[Learning experience of acupuncture technique from professor ZHANG Jin].

Science.gov (United States)

Xue, Hongsheng; Zhang, Jin

2017-08-12

As a famous acupuncturist in the world, professor ZHANG Jin believes the key of acupuncture technique is the use of force, and the understanding of the "concentrating the force into needle body" is essential to understand the essence of acupuncture technique. With deep study of Huangdi Neijing ( The Inner Canon of Huangdi ) and Zhenjiu Dacheng ( Compendium of Acupuncture and Moxibustion ), the author further learned professor ZHANG Jin 's theory and operation specification of "concentrating force into needle body, so the force arriving before and together with needle". The whole-body force should be subtly focused on the tip of needle, and gentle force at tip of needle could get significant reinforcing and reducing effect. In addition, proper timing at tip of needle could start reinforcing and reducing effect, lead qi to disease location, and achieve superior clinical efficacy.

Kim Dotcomi kättemaks / Andy Greenberg

Index Scriptorium Estoniae

Greenberg, Andy

2013-01-01

Skandaalne Internetimagnaat Kim Schmitz, rohkem tuntud kui Kim Dotcom, on veendunud, et tema loodud failivahetusprogrammi Megauploadi mahavõtmisega ja autoriõiguste rikkumise süüdistusega tehti talle liiga ning ta on asunud raevukalt vastulöögile USA valitsuse vastu

Development of megestrol acetate solid dispersion nanoparticles for enhanced oral delivery by using a supercritical antisolvent process

Directory of Open Access Journals (Sweden)

Ha ES

2015-08-01

Full Text Available Eun-Sol Ha,1 Jeong-Soo Kim,2 In-hwan Baek,3 Jin-Wook Yoo,1 Yunjin Jung,1 Hyung Ryong Moon,1 Min-Soo Kim1 1College of Pharmacy, Pusan National University, 2Dong-A ST Co Ltd, Yongin, 3College of Pharmacy, Kyungsung University, Busan, South Korea Abstract: In the present study, solid dispersion nanoparticles with a hydrophilic polymer and surfactant were developed using the supercritical antisolvent (SAS process to improve the dissolution and oral absorption of megestrol acetate. The physicochemical properties of the megestrol acetate solid dispersion nanoparticles were characterized using scanning electron microscopy, differential scanning calorimetry, powder X-ray diffraction, and a particle-size analyzer. The dissolution and oral bioavailability of the nanoparticles were also evaluated in rats. The mean particle size of all solid dispersion nanoparticles that were prepared was <500 nm. Powder X-ray diffraction and differential scanning calorimetry measurements showed that megestrol acetate was present in an amorphous or molecular dispersion state within the solid dispersion nanoparticles. Hydroxypropylmethyl cellulose (HPMC solid dispersion nanoparticles significantly increased the maximum dissolution when compared with polyvinylpyrrolidone K30 solid dispersion nanoparticles. The extent and rate of dissolution of megestrol acetate increased after the addition of a surfactant into the HPMC solid dispersion nanoparticles. The most effective surfactant was Ryoto sugar ester L1695, followed by d-a-tocopheryl polyethylene glycol 1000 succinate. In this study, the solid dispersion nanoparticles with a drug:HPMC:Ryoto sugar ester L1695 ratio of 1:2:1 showed >95% rapid dissolution within 30 minutes, in addition to good oral bioavailability, with approximately 4.0- and 5.5-fold higher area under the curve (0–24 hours and maximum concentration, respectively, than raw megestrol acetate powder. These results suggest that the preparation of megestrol

Měkkýši Národní přírodní rezervace Soos Molluscs (Mollusca of the Soos National Nature Reserve

Directory of Open Access Journals (Sweden)

Jitka Horáčková

2012-12-01

Full Text Available The Soos National Nature Reserve nearby Františkovy Lázně Town (Western Bohemia, Czech Republic is a spectacular peatbog site with the occurrence of fens on numerous mineral spring effluents, emanations of pure carbon dioxide in mofettes (i.e. false mud volcanoes, parts with saltwater wetlands, and diatomite mantel in its central part. These natural conditions affect general character of all habitats, vegetation and malacocoenoses in the reserve. Altogether, 31 mollusc species were found there, but only two of them are considered as near threatened (Pisidium obtusale and Vertigo substriata. The majority of recorded assemblage was composed of common and generalist mollusc species.

[Influences of Confucianism, Taoism and Buddhism on Chinese Medical Formulas in Jin-Tang Dynasties].

Science.gov (United States)

Wu, Xiao-xiang

2006-04-01

In the Jin-Tang Dynasties, when Confucianism, Taoism and Buddhism contended, conflicted and well blent, forming a state of mingled thoughts of the three sects. It exerted profound influences on Chinese Medical Formulas and promoted the academic fashion of compiling books about medical formulas characterized by collecting various formulas especially the simple and proved recipes. This plays a role in the formation of the formulas used in the Jin-Tang Dynasties, featuring simplicity, convenience, cheapness, and effectiveness, different from those of other periods.

Water footprint of Jing-Jin-Ji urban agglomeration in China

Science.gov (United States)

Zhao, D.

2017-12-01

A rapidly expanding economy and increasing water demand for economic production is placing enormous stress on water quantity and aquatic environment in Northern China, especially the so-called Jing-Jin-Ji (Beijing-Tianjin-Hebei) urban agglomeration. Several studies have focused on energy consumption, air pollution, CO2 emissions and regional blue water footprint (WF) following release of the Jing-Jin-Ji Integration Strategy by the China government. However, a comprehensive assessment distinguishing blue, green and grey WF amongst different industrial sectors, ascertaining how WF transfers internally and beyond the region and final demand consumption is not available. In this study, we quantified the WF and virtual water flow on a sectoral basis for the year 2010 through coupling the multi-regional input-output model (MRIO) with WF assessment. The results showed that Beijing and Tianjin are net importers of green, blue and grey water from Hebei and other provinces to support their needs. Conversely, Hebei exports all WF colors to Beijing, Tianjin and other provinces in China, more than 60% of WF is transferred as virtual water. For the overall Jing-Jin-Ji region a small amount of blue water (2,086 million m3) is exported, but huge amounts of green water (15,573 million m3) and grey water (30,620 million m3) are outsourced. A "Virtual Water Strategy" is one measure which could alleviate water stress at the regional scale, with consideration of financial compensation from water receiving regions made to water supplying regions for achieving water management targets. We also found that physical water transfer to Jing-Jin-Ji could not balance virtual blue water exports. Our research suggests that a continuation of an export-based economic development model will worsen Hebei's water stress. Reducing the dependency of Hebei's sectoral economy on export of water intensive and low value added agricultural products may be one strategy to reduce the pressure on regional water

Projecting Pyongyang: The Future of North Korea's Kim Jong IL Regime

National Research Council Canada - National Science Library

Scobell, Andrew

2008-01-01

.... In this monograph, the focus is on the fate of the regime dominated by the Kim Dynasty, initially ruled by Kim Il Sung and then led by his son, Kim Jong Il, following the former's death in 1994...

The ten thousand Kims

Science.gov (United States)

Baek, Seung Ki; Minnhagen, Petter; Kim, Beom Jun

2011-07-01

In Korean culture, the names of family members are recorded in special family books. This makes it possible to follow the distribution of Korean family names far back in history. It is shown here that these name distributions are well described by a simple null model, the random group formation (RGF) model. This model makes it possible to predict how the name distributions change and these predictions are shown to be borne out. In particular, the RGF model predicts that for married women entering a collection of family books in a certain year, the occurrence of the most common family name 'Kim' should be directly proportional to the total number of married women with the same proportionality constant for all the years. This prediction is also borne out to a high degree. We speculate that it reflects some inherent social stability in the Korean culture. In addition, we obtain an estimate of the total population of the Korean culture down to the year 500 AD, based on the RGF model, and find about ten thousand Kims.

The ten thousand Kims

International Nuclear Information System (INIS)

Baek, Seung Ki; Minnhagen, Petter; Kim, Beom Jun

2011-01-01

In Korean culture, the names of family members are recorded in special family books. This makes it possible to follow the distribution of Korean family names far back in history. It is shown here that these name distributions are well described by a simple null model, the random group formation (RGF) model. This model makes it possible to predict how the name distributions change and these predictions are shown to be borne out. In particular, the RGF model predicts that for married women entering a collection of family books in a certain year, the occurrence of the most common family name 'Kim' should be directly proportional to the total number of married women with the same proportionality constant for all the years. This prediction is also borne out to a high degree. We speculate that it reflects some inherent social stability in the Korean culture. In addition, we obtain an estimate of the total population of the Korean culture down to the year 500 AD, based on the RGF model, and find about ten thousand Kims.

Farmers of Jin county want fewer children.

Science.gov (United States)

Xiao, M

1986-04-01

The economic reform practiced in the vast rural areas in China gives a great impetus to the vigorous development of rural economy and the the rapid improvement of living standard. Meanwhile, reform pounds at the traditional childbearing ideas. The striking change in the childbearing attitudes of the farmers of the Jin County is a good example. As the farmers of the country are getting well-off when the commodity economy develops rapidly with the rural economic reforms, their childbearing attitudes change. Profound changes have taken place in their mode of production and their life style. The young couples of the county begin to seek small families instead of traditional big ones. They are convinced that under the new situation of reforms, the farmers of an old generation are in no way competent as the head of the family to guide production and therefore want to build their own small families by freeing themselves from the binds of the traditional patriarchal system. The increase in the cost of bringing up children and the economic loss resulting from the absence from work for looking after children constitute another reason to prefer a small family. The son is no more the only economic guarantee for the aged. As a result of the rapid development of the rural economy, a retirement system has been established among the farmers of the Jin county. "It is unreliable to expect that the son will support his aged parents. Now it is better to earn more money and the collective can be depended upon by the aged."

Expression of porcine myosin heavy chain 1 gene in Berkshire loins ...

African Journals Online (AJOL)

Expression of porcine myosin heavy chain 1 gene in Berkshire loins with a high pH24 value. Jin Hun Kang, Woo Young Bang, Eun Jung Kwon, Yong Hwa Lee, Da Hye Park, Eun Seok Cho, Min Ji Kim, Jong-Soon Choi, Hwa Chun Park, Beom Young Park, Chul Wook Kim ...

Colon-targeted delivery of piceatannol enhances anti-colitic effects of the natural product: potential molecular mechanisms for therapeutic enhancement

Directory of Open Access Journals (Sweden)

Yum S

2015-08-01

Full Text Available Soohwan Yum, Seongkeun Jeong, Sunyoung Lee, Joon Nam, Wooseong Kim, Jin-Wook Yoo, Min-Soo Kim, Bok Luel Lee, Yunjin Jung College of Pharmacy, Pusan National University, Busan, Republic of Korea Abstract: Piceatannol (PCT, an anti-colitic natural product, undergoes extensive Phase II hepatic metabolism, resulting in very low bioavailability. We investigated whether colon-targeted delivery of PCT could enhance anti-colitic effects and how therapeutic enhancement occurred at the molecular level. Molecular effects of PCT were examined in human colon carcinoma cells and inflamed colons. The anti-colitic effects of PCT in a colon-targeted capsule (colon-targeted PCT were compared with PCT in a gelatin capsule (conventional PCT in a trinitrobenzene sulfonic acid-induced rat colitis model. Colon-targeted PCT elicited greatly enhanced recovery of the colonic inflammation. In HCT116 cells, PCT inhibited nuclear factor kappaB while activating anti-colitic transcription factors, nuclear factor-erythroid 2 (NF-E2 p45-related factor 2, and hypoxia-inducible factor-1. Colon-targeted PCT, but not conventional PCT, modulated production of the target gene products of the transcription factors in the inflamed colonic tissues. Rectal administration of PCT, which simulates the therapeutic action of colon-targeted PCT, also ameliorated rat colitis and reproduced the molecular effects in the inflamed colonic tissues. Colon-targeted delivery increased therapeutic efficacy of PCT against colitis, likely resulting from multitargeted effects exerted by colon-targeted PCT. The drug delivery technique may be useful for therapeutic optimization of anti-colitic lead compounds including natural products. Keywords: piceatannol, colitis, colon-targeted delivery, multitarget, polypharmacology

Growth characteristics and productivity of cold-tolerant “Kowinearly ...

African Journals Online (AJOL)

Growth characteristics and productivity of cold-tolerant “Kowinearly” Italian ryegrass in the northern part of South Korea. Gi Jun Choi, Hee Chung Ji, Ki-Yong Kim, Hyung Soo Park, Sung Seo, Ki-Won Lee, Sang-Hoon Lee ...

Emissive lead(II) benzenedicarboxylate metal-organic frameworks

Indian Academy of Sciences (India)

Abdul Malik P Peedikakkal

2018-04-16

Apr 16, 2018 ... Jang E, Jun S, Jang H, Lim J, Kim B and Kim Y 2010. White-light-emitting ... 2837; (b) Li Y-F, Wang D, Liao Z, Kang Y, Ding. W-H, Zheng X-J, Jin L-P 2016 .... Zuo J-L and Zhou H-C 2007 Synthesis and Characteri- zations of a ...

Anmeldelse af Kim Wind Andersen: Overblik over selskabers underskudsfremførsel

DEFF Research Database (Denmark)

Werlauff, Erik

2011-01-01

Artiklen anmelder Kim Wind Andersen: Overblik over selskabers underskudsfremførsel (Thomson Reuters Professional, 2010)......Artiklen anmelder Kim Wind Andersen: Overblik over selskabers underskudsfremførsel (Thomson Reuters Professional, 2010)...

A Highly Responsive Silicon Nanowire/Amplifier MOSFET Hybrid Biosensor

Science.gov (United States)

2015-07-21

Hybrid Biosensor Jieun Lee1,2, Jaeman Jang1, Bongsik Choi1, Jinsu Yoon1, Jee-Yeon Kim3, Yang-Kyu Choi3, Dong Myong Kim1, Dae Hwan Kim1 & Sung-Jin Choi1...This study demonstrates a hybrid biosensor comprised of a silicon nanowire (SiNW) integrated with an amplifier MOSFET to improve the current response...of field-effect-transistor (FET)-based biosensors . The hybrid biosensor is fabricated using conventional CMOS technology, which has the potential

Improving dissolution and oral bioavailability of pranlukast hemihydrate by particle surface modification with surfactants and homogenization

Directory of Open Access Journals (Sweden)

Ha ES

2015-06-01

Full Text Available Eun-Sol Ha,1 In-hwan Baek,2 Jin-Wook Yoo,1 Yunjin Jung,1 Min-Soo Kim1 1College of Pharmacy, Pusan National University, 2College of Pharmacy, Kyungsung University, Busan, Republic of Korea Abstract: The present study was carried out to develop an oral formulation of pranlukast hemihydrate with improved dissolution and oral bioavailability using a surface-modified microparticle. Based on solubility measurements, surface-modified pranlukast hemihydrate microparticles were manufactured using the spray-drying method with hydroxypropylmethyl cellulose, sucrose laurate, and water and without the use of an organic solvent. The hydrophilicity of the surface-modified pranlukast hemihydrate microparticle increased, leading to enhanced dissolution and oral bioavailability of pranlukast hemihydrate without a change in crystallinity. The surface-modified microparticles with an hydroxypropylmethyl cellulose/sucrose laurate ratio of 1:2 showed rapid dissolution of up to 85% within 30 minutes in dissolution medium (pH 6.8 and oral bioavailability higher than that of the commercial product, with approximately 2.5-fold and 3.9-fold increases in area under the curve (AUC0→12 h and peak plasma concentration, respectively. Therefore, the surface-modified microparticle is an effective oral drug delivery system for the poorly water-soluble therapeutic pranlukast hemihydrate. Keywords: solubility, wettability, sucrose laurate, cellulose

AMS radiocarbon dating of cemetery of Jin Marquises in China

CERN Document Server

Wu, X; Wang, J; Guo, Z; Liu, K; Lü, X; Ma, H; Li, K; Yuan, J; Cai, L

2000-01-01

Bones are very important samples to determine the hosts of the cemetery of Jin Marquises which were excavated at Tianma-Qucun site in Shanxi Province in China. In order to obtain accurate AMS radiocarbon dates, bones were pretreated by two kinds of methods, the gelatin-extraction method and the amino-acid method. Charcoals collected from the same sites were also used. The measured dates agree with historical record.

REPRESENTATION OF KIM JONG-UN’S SUCCESSION IN BBC NEWS: A CRITICAL DISCOURSE ANALYSIS

Directory of Open Access Journals (Sweden)

Hendra Nugraha

2016-04-01

Full Text Available This research attempts to reveal representation of Kim Jong-Un’s succession in BBC News through textual and discursive practice analysis. The data of this thesis are taken from BBC News website on 29 and 31 December 2011. The theory applied to seek the objective of the research is Critical Discourse Analysis developed by Fairclough. Through textual and discursive practice analysis, the writer finds pthat BBC employs more passive material clauses than active material clauses in depicting Kim Jong-Un’s succession. BBC also represents Kim Jong-Un’s succession as premature process where Kim Jong-Un is portrayed as a young and inexperienced leader. Besides the prematurity of the succession, the present writer finds that BBC represents Kim Jong-Un’s succession as continuity of Kim’s family dynasty. Thus, the succession is based on his resemblance to Kim Il-Sung, the founder of Democratic People’s Republic of Korea, rather than Kim Jong-Un ability and competency.

The New North Korean Problem: History and Responsibilities in the Age of Kim Jong Un

Science.gov (United States)

2012-03-29

Kim Jong Un is the youngest of Kim Jong Il’s three male children. The oldest, Kim Jong Nam was once favored to...passport.49 In a series of interviews with Japanese reporter Yogi Gomi, Kim Jong Nam related his concerns about the future of North Korea and the...4. TITLE AND SUBTITLE THE NEW NORTH KOREAN PROBLEM: HISTORY AND RESPONSIBILITIES IN THE AGE OF KIM JONG UN 5. FUNDING NUMBERS

A 90-day study of sub-chronic oral toxicity of 20 nm positively charged zinc oxide nanoparticles in Sprague Dawley rats

Directory of Open Access Journals (Sweden)

Park HS

2014-12-01

Full Text Available Hark-Soo Park,1 Seon-Ju Kim,1 Taek-Jin Lee,1 Geon-Yong Kim,1 EunHo Meang,1 Jeong-Sup Hong,1 Su-Hyon Kim,1 Sang-Bum Koh,1 Seung-Guk Hong,1 Yle-Shik Sun,1 Jin Seok Kang,2 Yu-Ri Kim,3 Meyoung-Kon Kim,3 Jayoung Jeong,4 Jong-Kwon Lee,4 Woo-Chan Son,5 Jae-Hak Park61General Toxicology Team, Korea Testing and Research Institute, Seoul, 2Department of Biomedical Laboratory Science, Namseoul University, Cheonan, 3Department of Biochemistry and Molecular Biology, Korea University Medical School and College, Seoul, 4National Institute of Food and Drug Safety Evaluation, Seoul, 5Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, 6Laboratory Animal Medicine, College of Veterinary Medicine, Seoul National University, Seoul, KoreaPurpose: The study reported here was conducted to determine the systemic oral toxicity and to find the no-observed-adverse-effect level of 20 nm positively charged zinc oxide (ZnOSM,20(+ nanoparticles in Sprague Dawley rats for 90 days.Methods: For the 90-day toxicity study, the high dose was set as 500 mg per kg of body weight (mg/kg and the middle and low dose were set to 250 mg/kg and 125 mg/kg, respectively. The rats were held for a 14-day recovery period after the last administration, to observe for the persistence or reduction of any toxic effects. A distributional study was also carried out for the systemic distribution of ZnOSM,20(+ NPs.Results: No rats died during the test period. There were no significant clinical changes due to the test article during the experimental period in functional assessment, body weight, food and water consumption, ophthalmological testing, urine analysis, necropsy findings, or organ weights, but salivation was observed immediately after administration in both sexes. The total red blood cell count was increased, and hematocrit, albumin, mean cell volume, mean cell hemoglobin, and mean cell hemoglobin concentration were decreased significantly compared with

Lapset median käyttäjinä

OpenAIRE

Jalonen, Taru; Suomela, Sonja

2010-01-01

Laurea-ammattikorkeakoulu Tiivistelmä Hyvinkää Sosiaali-, terveys- ja liikunta-ala Hoitotyön koulutusohjelma Terveydenhoitaja AMK Sairaanhoitaja AMK Taru Jalonen, Sonja Suomela Lapset median käyttäjinä Vuosi ‎2010‎ Sivumäärä ‎63‎ Tämän opinnäytetyön tarkoituksena oli selvittää lasten tottumuksia ja kokemuksia mediasta sekä ‎niiden herättämiä tunteita. Lisäksi selvitimme lasten käyttämiä mediaympäristöjä sekä median ‎näkymistä lasten leikeissä. Tämä työ on os...

Study on embodied CO2 transfer between the Jing-Jin-Ji region and other regions in China: a quantification using an interregional input-output model.

Science.gov (United States)

Chen, Mengmeng; Wu, Sanmang; Lei, Yalin; Li, Shantong

2018-03-08

Jing-Jin-Ji region (i.e., Beijing, Tianjin, and Hebei) is China's key development region, but it is also the leading and most serious air pollution region in China. High fossil fuel consumption is the major source of both carbon dioxide (CO 2 ) emissions and air pollutants. Therefore, it is important to reveal the source of CO 2 emissions to control the air pollution in the Jing-Jin-Ji region. In this study, an interregional input-output model was applied to quantitatively estimate the embodied CO 2 transfer between Jing-Jin-Ji region and other region in China using China's interregional input-output data in 2010. The results indicated that there was a significant difference in the production-based CO 2 emissions in China, and furthermore, the Jing-Jin-Ji region and its surrounding regions were the main regions of the production-based CO 2 emissions in China. Hebei Province exported a large amount of embodied CO 2 to meet the investment, consumption, and export demands of Beijing and Tianjin. The Jing-Jin-Ji regions exported a great deal of embodied CO 2 to the coastal provinces of southeast China and imported it from neighboring provinces.

Interprovincial transfer of embodied energy between the Jing-Jin-Ji area and other provinces in China: A quantification using interprovincial input-output model.

Science.gov (United States)

Chen, Weiming; Wu, Sanmang; Lei, Yalin; Li, Shantong

2017-04-15

Commodity trade between regions implies a large amount of energy transfer. As an important economic growth pole of China, the Jing-Jin-Ji area (Beijing-Tianjin-Hebei) is also one of the areas with the largest energy consumption in China. Moreover, the primary energy consumer goods in this area are fossil fuels, such as coal. This has led to serious air pollution in the area. Therefore, the reduction of energy consumption under the premise of maintaining sustained economic growth is an important task of the Jing-Jin-Ji area. In this study, an interprovincial input-output model was applied to quantitatively estimate the embodied energy transfer between Jing-Jin-Ji area and other provinces in China. The results indicated that the Metal and nonmetal mineral processing industry and the Electrical, gas and water industry in the Jing-Jin-Ji area exported a large amount of embodied energy to the Yangtze River Delta and the Pearl River Delta. However, the embodied energy export of the Jing-Jin-Ji area mainly exported by Hebei province. Beijing and Tianjin even have some net import of embodied energy. The embodied energy transfer between Tianjin, Hebei and other provinces was mainly driven by investment, while the main media of embodied energy transfer between Beijing and other provinces was consumption. Therefore, we suggest that the Jing-Jin-Ji area should further increase the degree of dependence on other provinces' energy-intensive products and reduce the export of energy-intensive products. In addition, there should be difference in the energy and industrial policies among Beijing, Tianjin and Hebei, and the problems of high energy consumption and high proportion of heavy industry in Hebei should be first resolved. Copyright © 2017 Elsevier B.V. All rights reserved.

Drug–drug interaction of microdose and regular-dose omeprazole with a CYP2C19 inhibitor and inducer

OpenAIRE

Park G; Bae SH; Park W; Han S; Park M; Shin S; Shin YG; Yim DS

2017-01-01

Gab-jin Park,1 Soo Hyeon Bae,1 Wan-Su Park,1 Seunghoon Han,1 Min-Ho Park,2 Seok-Ho Shin,2 Young G Shin,2 Dong-Seok Yim1,2 1Department of Clinical Pharmacology and Therapeutics, Seoul St Mary’s Hospital, PIPET (Pharmacometrics Institute for Practical Education and Training), College of Medicine, Catholic University of Korea, Seoul, South Korea; 2College of Pharmacy, Chungnam National University, Daejeon, South Korea Purpose: A microdose drug–drug interaction (DDI) study may be a ...

TERT-CLPTM1 locus polymorphism (rs401681) is associated with the prognosis of hepatocellular carcinoma

OpenAIRE

Lee, Hye Won; Park, Won-Jin; Heo, Yu-Ran; Park, Tae In; Park, Soo Young; Lee, Jae-Ho

2017-01-01

Hye Won Lee,1,* Won-Jin Park,2,* Yu-Ran Heo,2 Tae In Park,3 Soo Young Park,4 Jae-Ho Lee2,* 1Department of Pathology, Keimyung University School of Medicine, Daegu, Republic of Korea; 2Department of Anatomy, Keimyung University School of Medicine, Daegu, Republic of Korea; 3Department of Pathology, Kyungpook National University School of Medicine, Daegu, Republic of Korea; 4Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Republic of Korea *T...

Research of Ancient Architectures in Jin-Fen Area Based on GIS&BIM Technology

Science.gov (United States)

Jia, Jing; Zheng, Qiuhong; Gao, Huiying; Sun, Hai

2017-05-01

The number of well-preserved ancient buildings located in Shanxi Province, enjoying the absolute maximum proportion of ancient architectures in China, is about 18418, among which, 9053 buildings have the structural style of wood frame. The value of the application of BIM (Building Information Modeling) and GIS (Geographic Information System) is gradually probed and testified in the corresponding fields of ancient architecture’s spatial distribution information management, routine maintenance and special conservation & restoration, the evaluation and simulation of related disasters, such as earthquake. The research objects are ancient architectures in JIN-FEN area, which were first investigated by Sicheng LIANG and recorded in his work of “Chinese ancient architectures survey report”. The research objects, i.e. the ancient architectures in Jin-Fen area include those in Sicheng LIANG’s investigation, and further adjustments were made through authors’ on-site investigation and literature searching & collection. During this research process, the spatial distributing Geodatabase of research objects is established utilizing GIS. The BIM components library for ancient buildings is formed combining on-site investigation data and precedent classic works, such as “Yingzao Fashi”, a treatise on architectural methods in Song Dynasty, “Yongle Encyclopedia” and “Gongcheng Zuofa Zeli”, case collections of engineering practice, by the Ministry of Construction of Qing Dynasty. A building of Guangsheng temple in Hongtong county is selected as an example to elaborate the BIM model construction process based on the BIM components library for ancient buildings. Based on the foregoing work results of spatial distribution data, attribute data of features, 3D graphic information and parametric building information model, the information management system for ancient architectures in Jin-Fen Area, utilizing GIS&BIM technology, could be constructed to support the

New integrable lattice hierarchies

International Nuclear Information System (INIS)

Pickering, Andrew; Zhu Zuonong

2006-01-01

In this Letter we give a new integrable four-field lattice hierarchy, associated to a new discrete spectral problem. We obtain our hierarchy as the compatibility condition of this spectral problem and an associated equation, constructed herein, for the time-evolution of eigenfunctions. We consider reductions of our hierarchy, which also of course admit discrete zero curvature representations, in detail. We find that our hierarchy includes many well-known integrable hierarchies as special cases, including the Toda lattice hierarchy, the modified Toda lattice hierarchy, the relativistic Toda lattice hierarchy, and the Volterra lattice hierarchy. We also obtain here a new integrable two-field lattice hierarchy, to which we give the name of Suris lattice hierarchy, since the first equation of this hierarchy has previously been given by Suris. The Hamiltonian structure of the Suris lattice hierarchy is obtained by means of a trace identity formula

q-Deformed KP Hierarchy and q-Deformed Constrained KP Hierarchy

OpenAIRE

He, Jingsong; Li, Yinghua; Cheng, Yi

2006-01-01

Using the determinant representation of gauge transformation operator, we have shown that the general form of $au$ function of the $q$-KP hierarchy is a $q$-deformed generalized Wronskian, which includes the $q$-deformed Wronskian as a special case. On the basis of these, we study the $q$-deformed constrained KP ($q$-cKP) hierarchy, i.e. $l$-constraints of $q$-KP hierarchy. Similar to the ordinary constrained KP (cKP) hierarchy, a large class of solutions of $q$-cKP hierarchy can be represent...

A differential-difference hierarchy associated with relativistic Toda and Volterra hierarchies

International Nuclear Information System (INIS)

Fan Engui; Dai Huihui

2008-01-01

By embedding a free function into a compatible zero curvature equation, we enlarge the original differential-difference hierarchy into a new hierarchy with the free function which still admits zero curvature representation. The new hierarchy not only includes the original hierarchy, but also the well-known relativistic Toda hierarchy and the Volterra hierarchy as special reductions by properly choosing the free function. Infinitely many conservation laws and Darboux transformation for a representative differential-difference system are constructed based on its Lax representation. The exact solutions follow by applying the Darboux transformation

Journal of Biosciences | Indian Academy of Sciences

Indian Academy of Sciences (India)

Author Affiliations. Eul-Won Hwang1 Kyung-A Kim1 Soo-Chul Park2 Mi-Jeong Jeong2 Myung-Ok Byun2 Hawk-Bin Kwon1. Division of Applied Biological Sciences, Sunmoon University, Asan, 336-708, Korea; Abiotic and Biotic Stress Team, National Institute of Agricultural Biotechnology, Suwon 441-707, Korea ...

Die brein soos beskou deur die Grieke en Romeine

Directory of Open Access Journals (Sweden)

Francois P. Retief

2015-02-01

Full Text Available In Ou Egipte is mummifikasie met uitgebreide reseksie of uitsnyding van organe geassosieer, maar geen kennis is geneem van die morfologie van die brein nie. Griekse skrywers van die sesde en vyfde eeue v.C. het die brein aanvanklik gesien as die setel van intelligensie, die orgaan van sensoriese waarneming en gedeeltelik die oorsprong van sperma. Pneuma het ’n belangrike rol in breinfunksie gespeel. Hippokrates was die eerste om die brein te beskryf as ’n dubbele orgaan, wat met harsingvlies (meninges bedek, funksioneel van pneuma afhanklik en vertolker van begrip is. Tydgenote soos Plato, Aristoteles en Diokles het tot die beskrywing bygedra, maar laasgenoemde twee het beweer dat die hart die middelpunt van intelligensie is en nie die brein nie. Gedurende die laaste helfte van die vierde eeu v.C. is disseksie van die menslike liggaam tydelik aan die mediese skool van Alexandrië toegelaat en het dit tot merkwaardige vooruitgang in die begrip van die menslike anatomie en fisiologie gelei. Herofilus en Erasistratus het uitstekende beskrywings van die struktuur en funksie van die brein gegee wat eers in die tweede eeu n.C. deur Galenus geëwenaar is.

Research of Ancient Architectures in Jin-Fen Area Based on GIS and BIM Technology

International Nuclear Information System (INIS)

Jia, Jing; Zheng, Qiuhong; Gao, Huiying; Sun, Hai

2017-01-01

The number of well-preserved ancient buildings located in Shanxi Province, enjoying the absolute maximum proportion of ancient architectures in China, is about 18418, among which, 9053 buildings have the structural style of wood frame. The value of the application of BIM (Building Information Modeling) and GIS (Geographic Information System) is gradually probed and testified in the corresponding fields of ancient architecture’s spatial distribution information management, routine maintenance and special conservation and restoration, the evaluation and simulation of related disasters, such as earthquake. The research objects are ancient architectures in JIN-FEN area, which were first investigated by Sicheng LIANG and recorded in his work of “Chinese ancient architectures survey report”. The research objects, i.e. the ancient architectures in Jin-Fen area include those in Sicheng LIANG’s investigation, and further adjustments were made through authors’ on-site investigation and literature searching and collection. During this research process, the spatial distributing Geodatabase of research objects is established utilizing GIS. The BIM components library for ancient buildings is formed combining on-site investigation data and precedent classic works, such as “Yingzao Fashi”, a treatise on architectural methods in Song Dynasty, “Yongle Encyclopedia” and “Gongcheng Zuofa Zeli”, case collections of engineering practice, by the Ministry of Construction of Qing Dynasty. A building of Guangsheng temple in Hongtong county is selected as an example to elaborate the BIM model construction process based on the BIM components library for ancient buildings. Based on the foregoing work results of spatial distribution data, attribute data of features, 3D graphic information and parametric building information model, the information management system for ancient architectures in Jin-Fen Area, utilizing GIS and BIM technology, could be constructed to support

A Propaganda Film Subverting Ethnic Hierarchy?: "Suicide Squad at the Watchtower" and Colonial Korea

Directory of Open Access Journals (Sweden)

Naoki Mizuno

2012-12-01

Full Text Available In the film "Suicide Squad at the Watchtower" (1943, the appearance of a Korean female physician carries with it the potential to subvert the film’s representation of the colonial ethnic hierarchy. The film’s director, Ch’oe In-gyu, had in his earlier film "Homeless Angels" presented the edifying message that a Korean female orphan could aspire to become a physician. This message was also incorporated into "Suicide Squad at the Watchtower." In these two films the story of a Korean woman who studies to become a physician (or at least desires to become one unfolds through the same actress, Kim Sin-jae. The suggestion that a Korean could achieve a social position equal to or even higher than a Japanese introduced the possibility of subverting the colonial ethnic hierarchy. But while the screenplay for the film had explicitly portrayed the female physician, the film version suppressed the representation, making it less evident. Nevertheless, it is possible to see "Suicide Squad at the Watchtower"’s enlightened message as an element with the potential to upset the ruling colonial order.

Even a monkey can understand fan activism: Political speech, artistic expression, and a public for the Japanese dôjin community

Directory of Open Access Journals (Sweden)

Alex Leavitt

2012-06-01

Full Text Available We examine the creation of dôjinshi works critiquing the passage of the metropolitan Tokyo ordinance Bill 156 in December 2010 as a case of fan-driven political activism. Bill 156 aims to limit artistic freedom and is specifically targeted at anime, manga, and other works of visual pop culture. Fans who participate in dôjin production perform both a love for this media and an active form of citizenship that is historically fannish but transformative beyond the mere appropriation and remix of media texts. We argue that dôjin fans and works constitute a recursive public, wherein participants actively create discourse around artistic and ideological issues while engaging in added layers of discourse regarding the maintenance of their existence as a public. We examine fan discourse and dôjin works engaging Bill 156 as an object for political activism, as anime and manga otaku perform their citizenship in the wider society of Japan for their local public and for a global audience of like-minded fans.

The (2+1)-dimensional nonisospectral relativistic Toda hierarchy related to the generalized discrete Painleve hierarchy

International Nuclear Information System (INIS)

Zhu Zuonong

2007-01-01

In this paper, we will concentrate on the topic of integrable discrete hierarchies in 2+1 dimensions, and their connection with discrete Painleve hierarchies. By considering a (2+1)-dimensional nonisospectral discrete linear problem, two new (2+1)-dimensional nonisospectral integrable lattice hierarchies-the 2+1 nonisospectral relativistic Toda lattice hierarchy and the 2+1 nonisospectral negative relativistic Toda lattice hierarchy-are constructed. It is shown that the reductions of the two new 2+1 nonisospectral lattice hierarchies lead to the (2+1)-dimensional nonisospectral Volterra lattice hierarchy and the (2+1)-dimensional nonisospectral negative Volterra lattice hierarchy. We also obtain two new (1+1)-dimensional nonisospectral integrable lattice hierarchies and two new ordinary difference hierarchies which are direct reductions of the two 2+1 nonisospectral integrable lattice hierarchies. One of the two difference hierarchies yields our previously obtained generalized discrete first Painleve (dP I ) hierarchy and another one yields a generalized alternative discrete second Painleve (alt-dP II ) hierarchy

The Measurement of Urbanization Level Based on Entity Space: A Case Study of JingJinJi Region, China

Directory of Open Access Journals (Sweden)

Wen Fenghua

2017-01-01

Full Text Available On the basis of analyzing the pros and cons of different urbanization level measurement methods, this paper puts forward urbanization level measurement method based on entity space and then uses entity space data to describe the urbanization rate of various districts and counties of JingJinJi Region in 2005 and 2009. According to the analysis of time and space differences on such basis, JingJinJi may be divided from high to low order according to the urbanization rate of the entity space: central urban area, urban development area and suburb, which respectively bear different functions. According to the comparison of entity space urbanization rate and population urbanization rate in the aspects of sequence, primacy ratio, zipf index, etc., we find the non-intensive land use status quo of urban development area of JingJinJi and the feature that the distribution of entity space urbanization scale is much uniform than distribution of population urbanization scale. Accordingly, the paper puts forward the following suggestions : (1 The space construction should depend upon function division; (2 The urban development area should pay attention to the construction of the supporting facilities and meanwhile enhance land use rate; (3 The urban construction should be enhanced in small and middle regions and counties surrounding Beijing and Tianjin.

Why hierarchies thrive.

Science.gov (United States)

Leavitt, Harold J

2003-03-01

Hardly anyone has a good word to say about hierarchies. Academics, consultants, and management gurus regularly forecast their imminent replacement because hierarchies--even when populated by considerate and intelligent people--can be cruel and stupid. They routinely transform motivated and loyal employees into disaffected Dilberts. It's no wonder that we continue to search for more humane and productive alternatives to them. Yet the intensity with which we struggle against hierarchies only serves to highlight their durability. Hierarchy, it seems, may be intrinsic not only to the natural world but also to our own natures. In this article, organizational behavior expert Harold J. Leavitt presents neither a defense of human hierarchies nor another attack on them. Instead, he offers a reality check, a reminder that hierarchy remains the basic structure of most, if not all, large, ongoing human organizations. That's because although they are often depicted as being out of date, hierarchies have proved to be extraordinarily adaptive. Over the past 50 years, for example, they have co-opted the three major managerial movements--human relations, analytic management, and communities of practice. Hierarchies also persist because they deliver real practical and psychological value, and they fulfill our deep need for order and security. Despite the good they may do, hierarchies are inevitably authoritarian. That authoritarianism shows up in all kinds of ways and influences everything in organizations, particularly communication. In multilevel organizations, for instance, messages get distorted as they travel up and down the ladder of command. Self-protection and self-interest weigh in, and relevant information is lost as messages make stops along the route. Sensitive leaders take steps to make speaking the truth as painless as possible. But it never is in organizations, because authoritarianism is an immutable element of hierarchy.

DsRed gene expression by doxycycline in porcine fibroblasts and ...

African Journals Online (AJOL)

DsRed gene expression by doxycycline in porcine fibroblasts and cloned embryos using transposon. SuJin Kim, JoonHo Moon, BegoRoibas da Torre, Islam M Saadeldin, JungTaek Kang, JiYei Choi, SolJi Park, Byeong-Chun Lee, Goo Jang Goo Jang ...

Fluorinated Materials for Air-stable and Moisture-resistant Flexible Optoelectronics

Science.gov (United States)

2014-01-02

Kim Jong , H.; Shin, S.; Yang, H.; An, B.-K.; Yang, L.; Park Soo, Y. Adv Mater 2012, 24, 911-915; (c) Geng, Y.; Li, H.-B.; Wu, S.-X.; Su, Z.-M. J...Park, J.-U.; Shir, D. J.-L.; Nam , Y.-S.; Jeon, S.; Rogers, J. A. Chem. Rev. 2007, 107, 1117-1160; (g) Murphy, A. R.; Frechet, J. M. J. Chem. Rev. 2007...2649-2655; (w) Song, H.-J.; Kim , D.-H.; Lee, E.-J.; Heo, S.-W.; Lee, J.-Y.; Moon, D.-K. Macromolecules (Washington, DC, U. S.) 2012, 45, 7815- 7822; (x

[Evaluation on efficacy of Jin's "Sanzhen" therapy combined with rehabilitation training for hemiplegia of stroke patients by Fugl-Meyer scale].

Science.gov (United States)

Han, De-Xiong; Zhuang, Li-Xing; Zhang, Ying

2011-06-01

To assess the therapeutic effect of Jin's "Sanzhen" therapy combined with rehabilitation training on limb-motor function of stroke patients by using Fugl-Meyer scale. A total of 254 hemiplegic stroke outpatients and inpatients from 7 hospitals were randomly divided into Jin's "Sanzhen" (JSZ) group (n = 83), rehabilitation group (n = 84) and combination group (n = 87). Acupuncture was applied to acupoints of Jin's "Sanzhen" including Quchi (LI 11), Waiguan (SJ 5) and Hegu (LI 4); Futu (ST 32). Zusanli (ST 36) and Sanyinjiao (SP 6); etc. The acupuncture needles were retained for 30 min after "Deqi". Rehabilitation training included passive joint movement, standing-sitting training, tapping-pressing stimulation, walking training, etc. The treatment was conducted once daily, 5 sessions a week and for 4 weeks. Fugl-Meyer scale composed of 100-point motor domain of the upper- and lower-extremity sections was used to assess the patients' motor function. On day 28 after the treatment, of the 83.84 and 87 hemiplegic stroke patients in the JSZ, rehabilitation and combination groups, 48 (57.8%), 31 (36.9%) and 50 (57.5%) experienced marked improvement in their clinical symptoms and signs, 26 (31.3%), 44 (52.4%) and 31(35.6%) had an improvement, and 9 (10.8%), 9 (10.7%) and 6 (6.9%) failed in the treatment, with the total effective rates being 89.2%, 89.3% and 93.1%, respectively. The neurological deficit score (NDS) of the combination group was significantly lower than that of the rehabilitation group (P rehabilitation groups (P rehabilitation groups in both NDS and FMAS (P > 0.05). Jin's "Sanzhen" therapy combined with rehabilitation training can significantly improve the limb motor function of hemiplegic stroke patients, and has a good synergistic effect.

North Korean Leadership Dynamics and Decision-making under Kim Jong-un: A First Year Assessment

Science.gov (United States)

2013-09-01

Kim Jong-un’s ’Sick’ Aunt Resurfaces,” Chosun Ilbo Online, 27 July 2013. Kim has a reported history of alcoholism and depression , which was...exacer- bated in the mid-2000s with her marital problems and the death of her daughter, Jang Kum-song, who committed suicide in 2006. Some reports claim...the Party and state apparatus. She was born in 1974, and, when in her teens , began work in Kim Il-sung’s Presidential Office. She moved over to the

Urinary KIM-1 and AQP-1 in patients with clear renal cell carcinoma: Potential noninvasive biomarkers

Directory of Open Access Journals (Sweden)

Mijušković Mirjana

2016-01-01

Full Text Available Background/Aim. Kidney injury molecule-1 (KIM-1 and aquaporin-1 (AQP-1 are potential early urinary biomarkers of clear renal cell carcinoma (cRCC. The aim of this study was to ascertain relationship between the urine concentrations KIM-1 and AQP-1 with tumor size, grade, pT stage and type of operation (radical or partial nephrectomy in patients with cRCC. Methods. Urinary concentrations of urinary KIM-1 (uKIM-1 and urinary AQP-1 (uAQP-1 were determined by commercially available ELISA kits. The analysis included 40 patients undergoing partial or radical nephrectomy for cRCC and 40 age- and sex-matched healthy adult volunteers. Results. The median preoperative concentrations of KIM-1 in the cRCC group [0.724 ± 1.120 ng/mg urinary creatinine (Ucr] were significantly greater compared with controls (healthy volunteers (0.210 ± 0.082 ng/mgUcr (p = 0.0227. Postoperatively, uKIM-1 concentration decreased significantly to control values (0.177 ± 0.099 ng/mgUcr vs 0.210 ± 0.082 ng/mgUcr, respectively. The size, grade and stage of tumor were correlated positively with preoperative uKIM-1 concentrations. Contrary to these results, concentrations of uAQP-1 in the cRCC group were significantly lower (0.111 ± 0.092 ng/mgUcr compared with the control group (0.202 ± 0.078 ng/mgUcr (p = 0.0014. Postoperatively, the concentrations of uAQP-1 increased progressively up to control values, approximately. We find no significant correlation between preoperative uAQP-1 concentrations and tumor size, grade and stage. Conclusion. uKIM-1 was found to be a reliable diagnostic marker of cRCC, based on its significantly increased values before and decreased values after the nephrectomy. [Projekat Ministarstva nauke Republike Srbije, br. III41018

Fermentation characteristics of Korean pear (Pyrus pyrifolia Nakai ...

African Journals Online (AJOL)

USER

2010-08-30

Aug 30, 2010 ... Dong Chung Kim1, Hee Jeong Chae2,3 and Man-Jin In1*. 1Department of Human ... 0.3% proteins and 0.2% lipids (Hwang and Park, 2006). It is primarily consumed as ..... Khan SH, Ansari FA (2007). Probiotics – the friendly ...

Constraints and Soliton Solutions for KdV Hierarchy and AKNS Hierarchy

International Nuclear Information System (INIS)

Li Nianhua; Li Yuqi

2011-01-01

It is well-known that the finite-gap solutions of the KdV equation can be generated by its recursion operator. We generalize the result to a special form of Lax pair, from which a method to constrain the integrable system to a lower-dimensional or fewer variable integrable system is proposed. A direct result is that the n-soliton solutions of the KdV hierarchy can be completely depicted by a series of ordinary differential equations (ODEs), which may be gotten by a simple but unfamiliar Lax pair. Furthermore the AKNS hierarchy is constrained to a series of univariate integrable hierarchies. The key is a special form of Lax pair for the AKNS hierarchy. It is proved that under the constraints all equations of the AKNS hierarchy are linearizable. (general)

Coenite seiklused ja Kim Ki-duki huumor / Merit Kask

Index Scriptorium Estoniae

Kask, Merit

2007-01-01

60-nda Cannes'i filmifestivali filme : Ethan ja Joel Coen'i "Pole maad vanadele meestele" ("No Country for Old Men" ; Ameerika Ühendriigid), Kim Ki-duki "Hingetõmme" ("Soom"/"Breath" ; Lõuna-Korea) ja Raphael Nadjari "Tehilim" (Prantsusmaa - Iisrael - Ameerika Ühendriigid)

Prikljutshenija Koenov i jumor Kim Ki-duka / Merit Kask

Index Scriptorium Estoniae

Kask, Merit

2007-01-01

60-nda Cannes'i filmifestivali filme : Ethan ja Joel Coen'i "Pole maad vanadele meestele" ("No Country for Old Men" ; Ameerika Ühendriigid), Kim Ki-duki "Hingetõmme" ("Soom"/"Breath" ; Lõuna-Korea) ja Raphael Nadjari "Tehilim" (Prantsusmaa - Iisrael - Ameerika Ühendriigid)

Chang Sei Kim's Activities on Public Health in Colonial Korea

Directory of Open Access Journals (Sweden)

Park Yunjae

2006-12-01

Full Text Available After graduating from Severance Medical College in 1916, Chang Sei Kim went to Shanghai to work as a missionary in a adventist hospital. The establishment of the Korean Provisional Government led him to participate in the independence movement. Educating nurses to assist the forthcoming war for independence, he seemed to realize the fact that the health of Koreans would be a key factor for achieving independence. He left for the U.S. to conduct comprehensive research on medicine. Chang Sei Kim was the first Korean to receive a Ph. D. degree of Public Health, graduating from the Johns Hopkins School of Hygiene and Public Health in 1925. He then gained an opportunity to work for Korea as a professor at Severance Medical College. His objective was the 'Reconstruction of the Korean People In Terms of Physical Constitution.' He pointed out that Koreans' weak state of health was a major reason for Korea's colonization. To gain independence, he emphasized that the Korean people should receive education on public health in order to improve the primitive conditions of sanitation. There is little doubt that Chang Sei Kim's ideas developed Heungsadan's views on medicine in terms of its stress on cultivation of ability, especially considering the fact that he was a member of the organization. As a member of the colonized who could not participate in the developing official policy, Chang Sei Kim was not able to implement his ideas fully, because an individual or a private organization could not carry out policy on public health as large a scale as the government did. Never giving up his hopes for Korean independence, he rejected requests to assume official posts in the Government-General. That was why he was particularly interested in the Self-Governing Movement in 1920s Korea. If the movement had attained its goal, he might have worked for the enhancement of sanitary environment as a director of Sanitary Department. His application for funding to establish

Bridging communication between public and government: a case study on kim surabaya

Science.gov (United States)

Aji, G. G.; Tsuroyya; Dewi, P. A. R.

2018-01-01

In democratic era, the public communication paradigm has shifted from a one-way socialization to more interactive one. As a consequence of freedom of speech, the public can Actively communicate with the government and vice versa. The problem is government is almost impossible to reach all public groups. Therefore, they has created the concept of social institutions as a communication hub between the government and its public, named the Kelompok Informasi Masyarakat (KIM). This research examines the activity of KIM in Surabaya on bridging public between government and the public. Using a case study approach, this research utilized various techniques of data collection such as: interviews, observation, and documentation. The results Showed that KIM plays a role in the two-way flow of information; to diseminate program and submit complaints and suggestions from the public about the policy. This study confirm the urgency of utilization on various channels in communicating with the public.

Novel electrosprayed nanospherules for enhanced aqueous solubility and oral bioavailability of poorly water-soluble fenofibrate

Directory of Open Access Journals (Sweden)

Yousaf AM

2016-01-01

Full Text Available Abid Mehmood Yousaf,1,2 Omer Mustapha,1 Dong Wuk Kim,1 Dong Shik Kim,1 Kyeong Soo Kim,1 Sung Giu Jin,1 Chul Soon Yong,3 Yu Seok Youn,4 Yu-Kyoung Oh,5 Jong Oh Kim,3 Han-Gon Choi1 1College of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan, Gyeonggi, South Korea; 2Faculty of Pharmacy, University of Central Punjab, Johar, Lahore, Pakistan; 3College of Pharmacy, Yeungnam University, Gyongsan, North Gyeongsang, 4School of Pharmacy, Sungkyunkwan University, Suwon, Gyeonggi, 5College of Pharmacy, Seoul National University, Seoul, South Korea Purpose: The purpose of the present research was to develop a novel electrosprayed nanospherule providing the most optimized aqueous solubility and oral bioavailability for poorly water-soluble fenofibrate.Methods: Numerous fenofibrate-loaded electrosprayed nanospherules were prepared with polyvinylpyrrolidone (PVP and Labrafil® M 2125 as carriers using the electrospray technique, and the effect of the carriers on drug solubility and solvation was assessed. The solid state characterization of an optimized formulation was conducted by scanning electron microscopy, powder X-ray diffraction, differential scanning calorimetry, and Fourier transform infrared spectroscopic analyses. Oral bioavailability in rats was also evaluated for the formulation of an optimized nanospherule in comparison with free drug and a conventional fenofibrate-loaded solid dispersion.Results: All of the electrosprayed nanospherule formulations had remarkably enhanced aqueous solubility and dissolution compared with free drug. Moreover, Labrafil M 2125, a surfactant, had a positive influence on the solubility and dissolution of the drug in the electrosprayed nanospherule. Increases were observed as the PVP/drug ratio increased to 4:1, but higher ratios gave no significant increases. In particular, an electrosprayed nanospherule composed of fenofibrate, PVP, and Labrafil M 2125 at the weight ratio of 1

Extracting Tag Hierarchies

Science.gov (United States)

Tibély, Gergely; Pollner, Péter; Vicsek, Tamás; Palla, Gergely

2013-01-01

Tagging items with descriptive annotations or keywords is a very natural way to compress and highlight information about the properties of the given entity. Over the years several methods have been proposed for extracting a hierarchy between the tags for systems with a "flat", egalitarian organization of the tags, which is very common when the tags correspond to free words given by numerous independent people. Here we present a complete framework for automated tag hierarchy extraction based on tag occurrence statistics. Along with proposing new algorithms, we are also introducing different quality measures enabling the detailed comparison of competing approaches from different aspects. Furthermore, we set up a synthetic, computer generated benchmark providing a versatile tool for testing, with a couple of tunable parameters capable of generating a wide range of test beds. Beside the computer generated input we also use real data in our studies, including a biological example with a pre-defined hierarchy between the tags. The encouraging similarity between the pre-defined and reconstructed hierarchy, as well as the seemingly meaningful hierarchies obtained for other real systems indicate that tag hierarchy extraction is a very promising direction for further research with a great potential for practical applications. Tags have become very prevalent nowadays in various online platforms ranging from blogs through scientific publications to protein databases. Furthermore, tagging systems dedicated for voluntary tagging of photos, films, books, etc. with free words are also becoming popular. The emerging large collections of tags associated with different objects are often referred to as folksonomies, highlighting their collaborative origin and the “flat” organization of the tags opposed to traditional hierarchical categorization. Adding a tag hierarchy corresponding to a given folksonomy can very effectively help narrowing or broadening the scope of search

Extracting tag hierarchies.

Directory of Open Access Journals (Sweden)

Gergely Tibély

Full Text Available Tagging items with descriptive annotations or keywords is a very natural way to compress and highlight information about the properties of the given entity. Over the years several methods have been proposed for extracting a hierarchy between the tags for systems with a "flat", egalitarian organization of the tags, which is very common when the tags correspond to free words given by numerous independent people. Here we present a complete framework for automated tag hierarchy extraction based on tag occurrence statistics. Along with proposing new algorithms, we are also introducing different quality measures enabling the detailed comparison of competing approaches from different aspects. Furthermore, we set up a synthetic, computer generated benchmark providing a versatile tool for testing, with a couple of tunable parameters capable of generating a wide range of test beds. Beside the computer generated input we also use real data in our studies, including a biological example with a pre-defined hierarchy between the tags. The encouraging similarity between the pre-defined and reconstructed hierarchy, as well as the seemingly meaningful hierarchies obtained for other real systems indicate that tag hierarchy extraction is a very promising direction for further research with a great potential for practical applications. Tags have become very prevalent nowadays in various online platforms ranging from blogs through scientific publications to protein databases. Furthermore, tagging systems dedicated for voluntary tagging of photos, films, books, etc. with free words are also becoming popular. The emerging large collections of tags associated with different objects are often referred to as folksonomies, highlighting their collaborative origin and the "flat" organization of the tags opposed to traditional hierarchical categorization. Adding a tag hierarchy corresponding to a given folksonomy can very effectively help narrowing or broadening the scope of

Extracting tag hierarchies.

Science.gov (United States)

Tibély, Gergely; Pollner, Péter; Vicsek, Tamás; Palla, Gergely

2013-01-01

Tagging items with descriptive annotations or keywords is a very natural way to compress and highlight information about the properties of the given entity. Over the years several methods have been proposed for extracting a hierarchy between the tags for systems with a "flat", egalitarian organization of the tags, which is very common when the tags correspond to free words given by numerous independent people. Here we present a complete framework for automated tag hierarchy extraction based on tag occurrence statistics. Along with proposing new algorithms, we are also introducing different quality measures enabling the detailed comparison of competing approaches from different aspects. Furthermore, we set up a synthetic, computer generated benchmark providing a versatile tool for testing, with a couple of tunable parameters capable of generating a wide range of test beds. Beside the computer generated input we also use real data in our studies, including a biological example with a pre-defined hierarchy between the tags. The encouraging similarity between the pre-defined and reconstructed hierarchy, as well as the seemingly meaningful hierarchies obtained for other real systems indicate that tag hierarchy extraction is a very promising direction for further research with a great potential for practical applications. Tags have become very prevalent nowadays in various online platforms ranging from blogs through scientific publications to protein databases. Furthermore, tagging systems dedicated for voluntary tagging of photos, films, books, etc. with free words are also becoming popular. The emerging large collections of tags associated with different objects are often referred to as folksonomies, highlighting their collaborative origin and the "flat" organization of the tags opposed to traditional hierarchical categorization. Adding a tag hierarchy corresponding to a given folksonomy can very effectively help narrowing or broadening the scope of search. Moreover

[KIM-1 and NGAL as potential biomarkers for the diagnosis and cancer progression].

Science.gov (United States)

Marchewka, Zofia; Tacik, Aneta; Piwowar, Agnieszka

2016-04-18

On the basis of scientific literature, there is growing evidence that KIM-1 and NGAL are interesting and promising biomarkers not only in acute and chronic inflammatory processes but also in oncogenesis. There are a number of studies which investigate their possible use in diagnosis, treatment and monitoring of therapy effectiveness. The results of recent research suggests that they may play an important role in standard oncology practice. Simultaneous measurement of KIM-1 and NGAL in urine can play a crucial role in carcinogenesis assessment and cancer progression. In the future, they can become rapid diagnostic indicators, which allow one to determine cancer subtype leading to biopsy replacement and therapy improvement. In the present work, beside biochemical characteristics of KIM-1 and NGAL, we will also discuss their role in the diagnosis and assessment of development of cancer.

KIM-1 and NGAL as potential biomarkers for the diagnosis and cancer progression

Directory of Open Access Journals (Sweden)

Zofia Marchewka

2016-04-01

Full Text Available On the basis of scientific literature, there is growing evidence that KIM-1 and NGAL are interesting and promising biomarkers not only in acute and chronic inflammatory processes but also in oncogenesis. There are a number of studies which investigate their possible use in diagnosis, treatment and monitoring of therapy effectiveness. The results of recent research suggests that they may play an important role in standard oncology practice. Simultaneous measurement of KIM-1 and NGAL in urine can play a crucial role in carcinogenesis assessment and cancer progression. In the future, they can become rapid diagnostic indicators, which allow one to determine cancer subtype leading to biopsy replacement and therapy improvement. In the present work, beside biochemical characteristics of KIM-1 and NGAL, we will also discuss their role in the diagnosis and assessment of development of cancer.

Design of a gelatin microparticle-containing self-microemulsifying formulation for enhanced oral bioavailability of dutasteride

Directory of Open Access Journals (Sweden)

Baek I

2015-06-01

Full Text Available In-hwan Baek,1,* Eun-Sol Ha,2,* Jin-Wook Yoo,2 Yunjin Jung,2 Min-Soo Kim21College of Pharmacy, Kyungsung University, 2College of Pharmacy, Pusan National University, Busan, Republic of Korea*These authors contributed equally to this workAbstract: In this study, a gelatin microparticle-containing self-microemulsifying formulation (SMF was developed using a spray-drying method to enhance the oral delivery of the poorly water-soluble therapeutic dutasteride. The effect of the amount of gelatin and the type and amount of hydrophilic additives, namely, Gelucire® 44/14, poloxamer 407, sodium lauryl sulfate, Soluplus®, Solutol™ HS15, and D-α-tocopheryl polyethylene glycol 1000 succinate, on the droplet size, dissolution, and oral absorption of dutasteride from the SMF was investigated. Upon dispersion of the gelatin microparticle-containing SMF in water after spray-drying, the mean droplet size of the aqueous dispersion was in the range of 110–137 nm. The in vitro dissolution and recrystallization results showed that gelatin could be used as a solid carrier and recrystallization inhibitor for the SMF of dutasteride. Furthermore, combination of the gelatin microparticle-containing SMF and Soluplus enhanced the dissolution properties and oral absorption of dutasteride. The results of our study suggest that the gelatin microparticle-containing SMF in combination with Soluplus could be useful to enhance the oral absorption of dutasteride.Keywords: dissolution, solubility, bioavailability, dutasteride

Increased therapeutic efficacy of a newly synthesized tyrosinase inhibitor by solid lipid nanoparticles in the topical treatment of hyperpigmentation

Directory of Open Access Journals (Sweden)

Al-Amin M

2016-12-01

Full Text Available Md Al-Amin, Jiafu Cao, Muhammad Naeem, Hasanul Banna, Min-Soo Kim, Yunjin Jung, Hae Young Chung, Hyung Ryong Moon, Jin-Wook Yoo College of Pharmacy, Pusan National University, Busan, South Korea Abstract: Hyperpigmentation caused by melanin overproduction is a major skin disorder in humans. Inhibition of tyrosinase, a key regulator of melanin production, has been used as an effective strategy to treat hyperpigmentation. In this study, we investigated the use of solid lipid nanoparticles (SLNs as a highly effective and nontoxic means to deliver a newly synthesized potent tyrosinase inhibitor, MHY498, and to target melanocytes through the skin. MHY498-loaded SLNs (MHY-SLNs were prepared by an oil-in-water emulsion solvent-evaporation method, and their morphological and physicochemical properties were characterized. MHY-SLNs showed a prolonged drug-release profile and higher skin permeation than that of MHY solution. In an in vivo evaluation of antimelanogenic activity, MHY-SLNs showed a prominent inhibitory effect against ultraviolet B-induced melanogenesis, resulting in no change in the skin color of C57BL/6 mouse, compared with that observed in an MHY solution-treated group and an untreated control group. The antimelanogenic effect of MHY-SLNs was further confirmed through Fontana–Masson staining. Importantly, MHY-SLNs did not induce any toxic effects in the L929 cell line. Overall, these data indicate that MHY-SLNs show promise in the topical treatment of hyperpigmentation. Keywords: melanogenesis, hyperpigmentation, MHY498, solid lipid nanoparticles, skin delivery

Comparative analysis of nanotechnology awareness in consumers and experts in South Korea

Directory of Open Access Journals (Sweden)

Kim YR

2014-12-01

Full Text Available Yu-Ri Kim,1 Eun Jeong Lee,1 Sung Ha Park,2 Hyo Jin Kwon,3 Seong Soo A An,4 Sang Wook Son,5 Young Rok Seo,6 Jae-Eun Pie,7 Myoung Yoon,8 Ja Hei Kim,8 Meyoung-Kon Kim1 1Department of Biochemistry and Molecular Biology, Korea University Medical School and College, Seoul, South Korea; 2Department of Biochemistry, University of Bath, Bath, UK; 3Department of Medical Education, Korea University Medical School and College, Seoul, South Korea; 4Department of Bionanotechnology, Gachon University, Seongnam, Gyeonggi, South Korea; 5Department of Dermatology, Korea University Medical School and College, Seoul, South Korea; 6Department of Life Science, Institute of Environmental Medicine for Green Chemistry, Dongguk University, Seoul, South Korea; 7Department of Food and Nutrition, College of Science and Engineering, Anyang University, Anyang, Gyeonggi, South Korea; 8Consumers Korea, Seoul, South Korea Purpose: This study examined the need for public communication about nanotechnologies and nanoparticles by providing a comparative analysis of the differences in risk awareness of nanotechnologies and nanoparticles between consumers and experts. Methods: A total of 1,007 consumers and 150 experts participated in this study. A questionnaire was prepared examining their awareness of nanotechnologies and nanomaterials and their view of the necessity for information and education about the latest nanotechnologies and nanomaterials. Results: Our results indicated that the expert group recognized that they knew more than consumers about nanotechnology and that there was a need for relevant education in nanotechnology and nanomaterials among consumers. We found that the consumer group had a more positive attitude toward nanotechnology, even though they did not know much about it. Moreover, the consumer group was inconclusive about the type of information on nanotechnology deemed necessary for the public, as well as the suitable party to be responsible for education

Interactive survey of consumer awareness of nanotechnologies and nanoparticles in consumer products in South Korea

Directory of Open Access Journals (Sweden)

Kim YR

2014-12-01

Full Text Available Yu-Ri Kim,1 Eun Jeong Lee,1 Sung Ha Park,2 Hyo Jin Kwon,3 Seong Soo A An,4 Sang Wook Son,5 Young Rok Seo,6 Jae-Eun Pie,7 Myoung Yoon,8 Ja Hei Kim,8 Meyoung-Kon Kim1 1Department of Biochemistry and Molecular Biology, Korea University Medical School and College, Seoul, South Korea; 2Department of Biochemistry, University of Bath, Bath, UK; 3Department of Medical Education, Korea University Medical School and College, Seoul, South Korea; 4Department of Bionanotechnology, Gachon University, Seongnam, South Korea; 5Department of Dermatology, Korea University Medical School and College, 6Department of Life Science, Institute of Environmental Medicine for Green Chemistry, Dongguk University, Seoul, South Korea; 7Department of Food and Nutrition, College of Science and Engineering, Anyang University, Anyang, Korea; 8Consumers Korea, Seoul, South Korea Background: The purpose of our study was to understand consumers' risk awareness and need for relevant information about nanotechnology and nanoparticles contained in products currently being sold in Korea. Methods: One thousand and seven adult consumers (aged 20–50 years were randomly selected from all over South Korea between November 1 and 9, 2010. We surveyed the origin and degree of their concern and their need for information and education regarding nanomaterials. Results: Analysis of the survey results showed no significant differences in responses by sex, age, and level of education, but significant differences were found in responses based on average monthly household income. Our research showed that consumers have vague expectations for and positive image of nanotechnology and nanoproducts but do not clearly understand what they are. In addition, we found that preparing and disseminating information to consumers is required in order to provide correct information about nanotechnology to the public. Conclusion: A communication system should be established among the multiple stakeholders involved

Generalized Miura transformations, two-bosons KP hierarchies and their reduction to KdV hierarchies

International Nuclear Information System (INIS)

Aratyn, H.; Ferreira, L.A.; Gomes, J.F.; Medeiros, R.T.; Zimerman, A.H.

1993-02-01

Bracket preserving gauge equivalence is established between several two-boson generated KP type of hierarchies. These KP hierarchies reduce under symplectic reduction (via Dirac constraints) to KdV and Schwarzian KdV hierarchies. Under this reduction the gauge equivalence is taking form of the conventional Miura maps between the above KdV type of hierarchies. (author). 16 refs

Generalized Miura transformations, two-bosons KP hierarchies and their reduction to KdV hierarchies

Energy Technology Data Exchange (ETDEWEB)

Aratyn, H. [Illinois Univ., Chicago, IL (United States). Dept. of Physics; Ferreira, L.A.; Gomes, J.F.; Medeiros, R.T.; Zimerman, A.H.

1993-02-01

Bracket preserving gauge equivalence is established between several two-boson generated KP type of hierarchies. These KP hierarchies reduce under symplectic reduction (via Dirac constraints) to KdV and Schwarzian KdV hierarchies. Under this reduction the gauge equivalence is taking form of the conventional Miura maps between the above KdV type of hierarchies. (author). 16 refs.

On the ILW hierarchy

International Nuclear Information System (INIS)

Tutiya, Y.; Satsuma, J.

2003-01-01

In this Letter, we present a new hierarchy which includes the intermediate long wave (ILW) equation at the lowest order. This hierarchy is thought to be a novel reduction of the 1st modified KP type hierarchy. The framework of our investigation is Sato theory

Integrable Hierarchies and Dispersionless Limit

OpenAIRE

Takasaki, Kanehisa; Takebe, Takashi

1994-01-01

Analogues of the KP and the Toda lattice hierarchy called dispersionless KP and Toda hierarchy are studied. Dressing operations in the dispersionless hierarchies are introduced as a canonical transformation, quantization of which is dressing operators of the ordinary KP and Toda hierarchy. An alternative construction of general solutions of the ordinary KP and Toda hierarchy is given as twistor construction which is quatization of the similar construction of solutions of dispersionless hierar...

Toda hierarchies and their applications

Science.gov (United States)

Takasaki, Kanehisa

2018-05-01

The 2D Toda hierarchy occupies a central position in the family of integrable hierarchies of the Toda type. The 1D Toda hierarchy and the Ablowitz–Ladik (aka relativistic Toda) hierarchy can be derived from the 2D Toda hierarchy as reductions. These integrable hierarchies have been applied to various problems of mathematics and mathematical physics since 1990s. A recent example is a series of studies on models of statistical mechanics called the melting crystal model. This research has revealed that the aforementioned two reductions of the 2D Toda hierarchy underlie two different melting crystal models. Technical clues are a fermionic realization of the quantum torus algebra, special algebraic relations therein called shift symmetries, and a matrix factorization problem. The two melting crystal models thus exhibit remarkable similarity with the Hermitian and unitary matrix models for which the two reductions of the 2D Toda hierarchy play the role of fundamental integrable structures.

The Impact of Land Use and Land Cover Change on Water Yield in the Jing- Jin-Ji Region in China

Science.gov (United States)

Li, Suxiao; Yang, Hong

2017-04-01

Water yield is one of the key ecosystem services sustaining both people's life and economic development. However, the water yield function is sensitive to anthropogenic activity especially the land use and land cover change (LUCC). Assessment of historical LUCC and its impact on water yield could benefit designing and implementing appropriate land use strategy that enhance the water yield capacity. Beijing (Jing) and its surrounding areas of Tianjin (Jin) and Hebei (Ji) is the political, cultural and economic center of China. The region is facing increasingly water crisis. Taking the Jing-Jin-Ji region as a study area, this study analyzed the historical LUCC and its impact on water yield by using the Integrated Valuation of Ecosystem Services and Tradeoffs (InVEST) model to spatially map and quantify the changes of water yield from 1995 to 2010. The results showed there was main decline in area of wetland and forest and increase in area of crop land and built up land. An abrupt decline in water yield was found for year 2000. The water yield was influenced to a great extent by precipitation and evapotranspiration, but the land use played an important role in the water yield capacity (water yield per unit area) through plant cover that affected evapotranspiration, soil water permeability and the capacity of holding the moisture content. By general ranking, the water yield capacity of different land use type was as follows: built-up>bare land>cropland> grassland>forest >wetland, which illustrated that the built-up and bare land had higher run off rate while the vegetation area had higher capacity to control surface run off to increase the groundwater. A good understanding of temporal-spatial allocation of historical LUCC and Water yield of the Jing-Jin-Ji region could help guide land use policy decisions that take into consideration of tradeoffs with respect to spatial distribution of ecosystem services amongst the three administrative entities (Jing-Jin-Ji) and

Docetaxel-loaded multilayer nanoparticles with nanodroplets for cancer therapy

OpenAIRE

Oh, Keun Sang; Kim, Kyungim; Yoon, Byeong Deok; Lee, Hye Jin; Park, Dal Yong; Kim, Eun-yeong; Lee, Kiho; Seo, Jae Hong; Yuk, Soon Hong

2016-01-01

Keun Sang Oh,1,* Kyungim Kim,1,* Byeong Deok Yoon,1 Hye Jin Lee,1 Dal Yong Park,1 Eun-yeong Kim,1 Kiho Lee,1 Jae Hong Seo,2 Soon Hong Yuk1,2 1College of Pharmacy, Korea University, Sejong, 2Biomedical Research Center, Korea University Guro Hospital, Guro-gu, Seoul, Republic of Korea *These authors contributed equally to this work Abstract: A mixture of docetaxel (DTX) and Solutol® HS 15 (Solutol) transiently formed nanodroplets when it was suspended in an aqueous medium. However, n...

Pharmacokinetic and bioequivalence study of a telmisartan/S-amlodipine fixed-dose combination (CKD-828) formulation and coadministered telmisartan and S-amlodipine in healthy subjects

OpenAIRE

Kang,Woo Youl; Seong,Sook Jin; Ohk,Boram; Gwon,Mi-Ri; Kim,Bo Kyung; La,Sookie; Kim,Hyun-Ju; Cho,Seungil; Yoon,Young-Ran; Yang,Dong Heon; Lee,Hae Won

2018-01-01

Woo Youl Kang,1,2,* Sook Jin Seong,1,* Boram Ohk,1,2 Mi-Ri Gwon,1,3 Bo Kyung Kim,1,2 Sookie La,4 Hyun-Ju Kim,3 Seungil Cho,1 Young-Ran Yoon,1,2 Dong Heon Yang,5 Hae Won Lee1 1Clinical Trial Center, Kyungpook National University Hospital, Daegu, Republic of Korea; 2Department of Biomedical Science, BK21 Plus KNU Bio-Medical Convergence Program for Creative Talent, Kyungpook National University Graduate School, Daegu, Republic of Korea; 3Department of Molecular Medicine, Cell and Matrix Resear...

North Korean Leadership Dynamics and Decision-making under Kim Jong-un: A Second Year Assessment

Science.gov (United States)

2014-03-01

Kim Kyong-hui was critically ill. Kim has a reported history of alcoholism and depression , which was exacerbated in the mid-2000s with her mari- tal...problems and the death of her daughter, Jang Kum-song, who com- mitted suicide in 2006. Some reports claim that she is also suffering from... teens , were

Grassmannian approach to super-KP hierarchies

International Nuclear Information System (INIS)

Takama, Michiaki.

1995-06-01

We present a theory of 'maximal' super-KP (SKP) hierarchy whose flows are maximally extended to include all those of known SKP hierarchies, including, for example, the MRSKP hierarchy of Manin and Radul and the Jacobian SKP (JSKP) introduced by Mulase and Rabin. It is shown that SKP hierarchies has a natural field theoretic description in terms of the B-C system, in analogous way as the ordinary KP hierarchy. For this SKP hierarchy, we construct the vertex operators by using Kac-van de Leur superbosonization. The vertex operators act on the τ-function and then produce the wave function and the dual wave function of the hierarchy. Thereby we achieve the description of the 'maximal' SKP hierarchy in terms of the τ-function, which seemed to be lacking till now. Mutual relations among the SKP hierarchies are clarified. The MRSKP and the JSKP hierarchies are obtained as special cases when the time variables are appropriately restricted. (author)

Lõuna-Korea teatel võib Kim peagi surra / Evelyn Kaldoja

Index Scriptorium Estoniae

Kaldoja, Evelyn, 1980-

2009-01-01

Viidates Lõuna-Korea ja Hiina luureandmetele, väidab Lõuna-Korea meedia, et Põhja-Korea liidril Kim Jong-ilil on kõhunäärmevähk ja talle pole antud elada rohkem kui 5 aastat. Põhja-Korea valitsejadünastia

Special polynomials associated with some hierarchies

International Nuclear Information System (INIS)

Kudryashov, Nikolai A.

2008-01-01

Special polynomials associated with rational solutions of a hierarchy of equations of Painleve type are introduced. The hierarchy arises by similarity reduction from the Fordy-Gibbons hierarchy of partial differential equations. Some relations for these special polynomials are given. Differential-difference hierarchies for finding special polynomials are presented. These formulae allow us to obtain special polynomials associated with the hierarchy studied. It is shown that rational solutions of members of the Schwarz-Sawada-Kotera, the Schwarz-Kaup-Kupershmidt, the Fordy-Gibbons, the Sawada-Kotera and the Kaup-Kupershmidt hierarchies can be expressed through special polynomials of the hierarchy studied

Monte Carlo lattice program KIM

International Nuclear Information System (INIS)

Cupini, E.; De Matteis, A.; Simonini, R.

1980-01-01

The Monte Carlo program KIM solves the steady-state linear neutron transport equation for a fixed-source problem or, by successive fixed-source runs, for the eigenvalue problem, in a two-dimensional thermal reactor lattice. Fluxes and reaction rates are the main quantities computed by the program, from which power distribution and few-group averaged cross sections are derived. The simulation ranges from 10 MeV to zero and includes anisotropic and inelastic scattering in the fast energy region, the epithermal Doppler broadening of the resonances of some nuclides, and the thermalization phenomenon by taking into account the thermal velocity distribution of some molecules. Besides the well known combinatorial geometry, the program allows complex configurations to be represented by a discrete set of points, an approach greatly improving calculation speed

Compound mitochondrial DNA mutations in a neurological patient ...

Indian Academy of Sciences (India)

Compound mitochondrial DNA mutations in a neurological patient with ataxia, myoclonus and deafness. Ji Hoon Park, Bo Ram Yoon, Hye Jin Kim, Phil Hyu Lee, Byung-Ok Choi and Ki Wha Chung. J. Genet. 93, 173–177. Table 1. Variations from the whole mtDNA sequence in the AMDF patient. Mutation. Report. Locus/ ...

Safety assessment of silica and zinc oxide nanoparticles

OpenAIRE

An, Seong Soo A; Kim, Meyoung-Kon

2014-01-01

Seong Soo A An,1 Meyoung-Kon Kim2 1Department of Bionanotechnology, Gachon Medical Research Institute, Gachon University, Seongnam, Gyeonggi, Korea; 2Department of Biochemistry and Molecular Biology, Korea University Medical School and College, Seoul, KoreaThe current volume is a special issue focusing on a safety assessment of nanoparticles, from their physicochemical properties to government regulations. It features twenty-five papers, discussing general issues with the possible harmfulness...

On self-dual Yang-Mills hierarchy

International Nuclear Information System (INIS)

Nakamura, Yoshimasa

1989-01-01

In this note, motivated by the Kadomtsev-Petviashvili (KP) hierarchy of integrable nonlinear evolution equations, a GL(n,C) self-dual Yang-Mills (SDYM) hierarchy is presented; it is an infinite system of SDYM equations having an infinite number of independent variables and being outside of the KP hierarchy. A relationship between the KP hierarchy and the SDYM hierarchy is discussed. It is also shown that GL(∞) SDYM equations introduced in this note are reduced to the GL(n,C) SDYM hierarchy by imposing an algebraic constraint. (orig.)

Recursion Operators for Dispersionless KP Hierarchy

International Nuclear Information System (INIS)

Cheng Qiusheng; He Jingsong

2012-01-01

Based on the corresponding theorem between dispersionless KP (dKP) hierarchy and ħ-dependent KP (ħKP) hierarchy, a general formal representation of the recursion operators for dKP hierarchy under n-reduction is given in a systematical way from the corresponding ħKP hierarchy. To illustrate this method, the recursion operators for dKP hierarchy under 2-reduction and 3-reduction are calculated in detail.

Extension of noncommutative soliton hierarchies

International Nuclear Information System (INIS)

Dimakis, Aristophanes; Mueller-Hoissen, Folkert

2004-01-01

A linear system, which generates a Moyal-deformed two-dimensional soliton equation as an integrability condition, can be extended to a three-dimensional linear system, treating the deformation parameter as an additional coordinate. The supplementary integrability conditions result in a first-order differential equation with respect to the deformation parameter, the flow of which commutes with the flow of the deformed soliton equation. In this way, a deformed soliton hierarchy can be extended to a bigger hierarchy by including the corresponding deformation equations. We prove the extended hierarchy properties for the deformed AKNS hierarchy, and specialize to the cases of deformed NLS, KdV and mKdV hierarchies. Corresponding results are also obtained for the deformed KP hierarchy. A deformation equation determines a kind of Seiberg-Witten map from classical solutions to solutions of the respective 'noncommutative' deformed equation

On the supersymmetric BKP hierarchy

International Nuclear Information System (INIS)

Ramos, Eduardo; Stanciu, Sonia

1994-01-01

We prove that the supersymmetric BKP-hierarchy of Yu (SBKP 2 ) is hamiltonian with respect to a nonlinear extension of the N=1 super-Virasoro algebra (W SBKP ) by fields of spin k, where k>[3]/[2] and 2k≡0,3 (mod 4). Moreover, we show how to associate in a similar manner an N=1 W-superalgebra with every integrable hierarchy of the SKdV-type. We also show using dressing transformations how to extend, in a way which is compatible with the hamiltonian structure, the SBKP 2 hierarchy by odd flows, as well as the equivalence of this extended hierarchy to the SBKP-hierarchy of Manin-Radul. ((orig.))

Higher-Order Hierarchies

DEFF Research Database (Denmark)

Ernst, Erik

2003-01-01

This paper introduces the notion of higher-order inheritance hierarchies. They are useful because they provide well-known benefits of object-orientation at the level of entire hierarchies-benefits which are not available with current approaches. Three facets must be adressed: First, it must be po...

Against the Nihilism of Suffering and Death: Richard E. K. Kim and His Works

Directory of Open Access Journals (Sweden)

Jooyeon Rhee

2016-03-01

Full Text Available This article examines the life and works of Richard E. K. Kim (1932–2009, a first-generation Korean diasporic writer in the United States. It focuses on how Kim struggled to overcome the nihilism of suffering and death that derived from colonialism and the Korean War through his literary works. Kim witnessed firsthand these two major historical events, which caused irrevocable psychological and physical damage to many people of his generation. In his autobiographical fiction, he conveys painful memories of the events by reviving the voices of people in that era. What his works offer us goes beyond vivid memories of the past, however; they also present the power of forgiveness as a condition to overcome the nihilism of suffering and death. Remembrance and forgiveness are, therefore, two major thematic pillars of his works that enable us to connect to these difficult and traumatic times. These themes are portrayed in such a gripping way mainly because Kim tried to maintain a certain distance—an emotional and linguistic distance—from the familiar, in order to elucidate the reality of the human condition: an ontological position of the exile from which he produced his works. This article argues that Kim’s works provide us the possibility to transcend the nihilism of historical trauma through articulating the meaning of remembrance and forgiveness from his self-assumed position of exile.

Integral hierarchies and percolation

International Nuclear Information System (INIS)

Klein, W.; Stell, G.

1985-01-01

For a variation of the Potts model which has been shown to describe continuum percolation, we derive a hierarchy of integral equations of Kirkwood-Salsburg type. The distribution functions which are the solutions of this hierarchy can be simply related to the connectedness functions in continuum percolation. From this hierarchy a second set of equations is derived from which the connectedness functions can be obtained directly. This approach is extremely useful when investigating properties of systems far from the percolation transition. These hierarchies are solved exactly in the mean-field (Kac-Baker) limit and possible implications for cluster growth are discussed. The relation between the Potts model for continuum percolation and the Widom-Rowlinson model is also noted

Functional representations of integrable hierarchies

International Nuclear Information System (INIS)

Dimakis, Aristophanes; Mueller-Hoissen, Folkert

2006-01-01

We consider a general framework for integrable hierarchies in Lax form and derive certain universal equations from which 'functional representations' of particular hierarchies (such as KP, discrete KP, mKP, AKNS), i.e. formulations in terms of functional equations, are systematically and quite easily obtained. The formalism genuinely applies to hierarchies where the dependent variables live in a noncommutative (typically matrix) algebra. The obtained functional representations can be understood as 'noncommutative' analogues of 'Fay identities' for the KP hierarchy

An extended Harry Dym hierarchy

International Nuclear Information System (INIS)

Ma Wenxiu

2010-01-01

An extended Harry Dym hierarchy is constructed by using eigenfunctions and adjoint eigenfunctions of the spectral problems of the Harry Dym hierarchy associated with the pseudo-differential operator L = u∂ + u 0 + u 1 ∂ -1 + .... The corresponding Lax presentation possesses a self-consistent source involving squared eigenfunctions. The resulting extended Harry Dym hierarchy is reduced to the Harry Dym hierarchy with self-consistent sources under the n-reduction, L n = (L n ) ≥2 , and the k-constrained Harry Dym hierarchy under the k-constraint, L k = (L k ) ≥2 + Σ N i=1 q i ∂ -1 r i ∂ 2 . A few particular examples are computed, together with their Lax pairs.

A note on the dispersionless BKP hierarchy

International Nuclear Information System (INIS)

Chen, Y.-T.; Tu, M.-H.

2006-01-01

We study the integrable hierarchy underlying topological Landau-Ginzburg models of D-type proposed by Takasaki. Since this integrable hierarchy contains the dBKP hierarchy as a sub-hierarchy, we refer it to the extended dBKP (EdBKP) hierarchy. We give a dressing formulation to the EdBKP hierarchy and investigate additional symmetries associated with the solution space of the hierarchy. We obtain hodograph solutions of its finite-dimensional reductions via Riemann-Hilbert problem (twistor construction) and derive Baecklund transformations of the (2 + 1)-dimensional dBKP equation from additional flows. Finally, the modified partner of the dBKP hierarchy is also established through a Miura transformation

Global Policing and the Case of Kim Dotcom

OpenAIRE

Darren Palmer; Ian J Warren

2013-01-01

In early 2012, 76 heavily armed police conducted a raid on a house in Auckland, New Zealand. The targets were Kim Dotcom, a German national with a NZ residency visa, and several colleagues affiliated with Megaupload, an online subscription-based peer-to-peer (P2P) file sharing facility. The alleged offences involved facilitating unlawful file sharing and United States federal criminal copyright violations. Following the raid, several court cases provide valuable insights into emerging ‘global...

The impact of the "Air Pollution Prevention and Control Action Plan" on PM2.5 concentrations in Jing-Jin-Ji region during 2012-2020.

Science.gov (United States)

Cai, Siyi; Wang, Yangjun; Zhao, Bin; Wang, Shuxiao; Chang, Xing; Hao, Jiming

2017-02-15

In order to cope with heavy haze pollution in China, the Air Pollution Prevention and Control Action Plan including phased goals of the fine particulate matter (PM 2.5 ) was issued in 2013. In this study, China's emission inventories in the baseline 2012 and the future scenarios of 2017 and 2020 have been developed based on this Action Plan. Beijing-Tianjin-Hebei (Jing-Jin-Ji) region, one of the most polluted regions in China, was taken as a case to assess the impact of phased emission control measures on PM 2.5 concentration reduction using WRF-CMAQ model system. With the implementation of the Action Plan, the emissions of sulfur dioxide (SO 2 ), nitrogen oxides (NO X ) , PM 2.5 , non-methane volatile organic compound (NMVOC), and ammonia (NH 3 ) in 2017 will decrease by36%, 31%, 30%,12%, and -10% from the 2012 levels in Jing-Jin-Ji, respectively. In 2020, the emissions of SO 2 , NO X, PM 2.5 , NMVOC, and NH 3 will decrease by 40%, 44%, 40%, 22%, and -3% from the 2012 levels in Jing-Jin-Ji, respectively. Consequently, the ambient annual PM 2.5 concentration under the scenarios of 2017 and 2020 will be 28.3% and 37.8% lower than those in 2012, respectively. The Action Plan provided an effective approach to alleviate PM 2.5 pollution level in Jing-Jin-Ji region. However, emission control of NMVOC and NH 3 should be paid more attention and be strengthened in future. Meanwhile, emission control of NO x , SO 2 , NH 3 and NMVOC synergistically are highly needed in the future because multiple pollutants impact on PM 2.5 and O 3 concentrations nonlinearly. Copyright © 2016 Elsevier B.V. All rights reserved.

Ab initio and Gordon--Kim intermolecular potentials for two nitrogen molecules

International Nuclear Information System (INIS)

Ree, F.H.; Winter, N.W.

1980-01-01

Both ab initio MO--LCAO--SCF and the electron-gas (or Gordon--Kim) methods have been used to compute the intermolecular potential (Phi) of N 2 molecules for seven different N 2 --N 2 orientations. The ab initio calculations were carried out using a [4s3p] contracted Gaussian basis set with and without 3d polarization functions. The larger basis set provides adequate results for Phi>0.002 hartree or intermolecular separations less than 6.5--7 bohr. We use a convenient analytic expression to represent the ab initio data in terms of the intermolecular distance and three angles defining the orientations of the two N 2 molecules. The Gordon--Kim method with Rae's self-exchange correction yields Phi, which agrees reasonably well over a large repulsive range. However, a detailed comparison of the electron kinetic energy contributions shows a large difference between the ab initio and the Gordon--Kim calculations. Using the ab initio data we derive an atom--atom potential of the two N 2 molecules. Although this expression does not accurately fit the data at some orientations, its spherical average agrees with the corresponding average of the ab initio Phi remarkably well. The spherically averaged ab initio Phi is also compared with the corresponding quantities derived from experimental considerations. The approach of the ab initio Phi to the classical quadrupole--quadrupole interaction at large intermolecular separation is also discussed

Effectiveness of Traditional Chinese Medicine Compound JieDuTongLuoShengJin Granules Treatment in Primary Sjögren’s Syndrome: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Directory of Open Access Journals (Sweden)

Ben Li

2017-01-01

Full Text Available Objective. To evaluate the clinical therapeutic efficacy and safety of JieDuTongLuoShengJin granules + HCQ in patients with pSS. Methods. 40 patients with low-activity-level pSS and without visceral involvement participated in this study and were randomized to receive either JieDuTongLuoShengJin granules with HCQ or placebo with HCQ. Patients and investigators were blinded to treatment allocation. The primary endpoint was week 12 ESSPRI score, while secondary endpoints included ESSDAI, salivary and lacrimal gland function, and some laboratory variables. Safety-related data were also assessed. Results. Comparing with the placebo group, the treatment group experienced statistically significant improvement in the mean change from baseline for the primary endpoint of ESSPRI score and also in PGA. Moreover, in comparison with baseline values, the treatment group had significantly improved ESSDAI score, unstimulated saliva flow rate, and several laboratory variables. However, upon comparison of the two groups, there were no significant differences for them. The incidence of AEs was 10.0%, one in treatment group and three in placebo group. Conclusion. Treatment with a combination of JieDuTongLuoShengJin granules with HCQ is effective in improving patients’ subjective symptoms and some objective indicators of pSS. These results indicate that JieDuTongLuoShengJin is promising as a safe and effective treatment of pSS.

Kim C. Sturgess. Shakespeare and the American Nation.

OpenAIRE

Claret, Jean‑Louis

2006-01-01

The front page of Kim C Sturgess’s recent book entitled Shakespeare and the American Nation is particularly mind‑teasing insofar as it represents the famous Droeshout engraving of the bard (it illustrated the front‑page of the 1623 edition of Shakespeare’s works) standing out against a background that superimposes the head of the Statue of Liberty on the spangled banner. The starting point of Sturgess’s 234‑page demonstration endorsed by Cambridge University Press is a paradox that the Britis...

Information slows down hierarchy growth.

Science.gov (United States)

Czaplicka, Agnieszka; Suchecki, Krzysztof; Miñano, Borja; Trias, Miquel; Hołyst, Janusz A

2014-06-01

We consider models of growing multilevel systems wherein the growth process is driven by rules of tournament selection. A system can be conceived as an evolving tree with a new node being attached to a contestant node at the best hierarchy level (a level nearest to the tree root). The proposed evolution reflects limited information on system properties available to new nodes. It can also be expressed in terms of population dynamics. Two models are considered: a constant tournament (CT) model wherein the number of tournament participants is constant throughout system evolution, and a proportional tournament (PT) model where this number increases proportionally to the growing size of the system itself. The results of analytical calculations based on a rate equation fit well to numerical simulations for both models. In the CT model all hierarchy levels emerge, but the birth time of a consecutive hierarchy level increases exponentially or faster for each new level. The number of nodes at the first hierarchy level grows logarithmically in time, while the size of the last, "worst" hierarchy level oscillates quasi-log-periodically. In the PT model, the occupations of the first two hierarchy levels increase linearly, but worse hierarchy levels either do not emerge at all or appear only by chance in the early stage of system evolution to further stop growing at all. The results allow us to conclude that information available to each new node in tournament dynamics restrains the emergence of new hierarchy levels and that it is the absolute amount of information, not relative, which governs such behavior.

Information slows down hierarchy growth

Science.gov (United States)

Czaplicka, Agnieszka; Suchecki, Krzysztof; Miñano, Borja; Trias, Miquel; Hołyst, Janusz A.

2014-06-01

We consider models of growing multilevel systems wherein the growth process is driven by rules of tournament selection. A system can be conceived as an evolving tree with a new node being attached to a contestant node at the best hierarchy level (a level nearest to the tree root). The proposed evolution reflects limited information on system properties available to new nodes. It can also be expressed in terms of population dynamics. Two models are considered: a constant tournament (CT) model wherein the number of tournament participants is constant throughout system evolution, and a proportional tournament (PT) model where this number increases proportionally to the growing size of the system itself. The results of analytical calculations based on a rate equation fit well to numerical simulations for both models. In the CT model all hierarchy levels emerge, but the birth time of a consecutive hierarchy level increases exponentially or faster for each new level. The number of nodes at the first hierarchy level grows logarithmically in time, while the size of the last, "worst" hierarchy level oscillates quasi-log-periodically. In the PT model, the occupations of the first two hierarchy levels increase linearly, but worse hierarchy levels either do not emerge at all or appear only by chance in the early stage of system evolution to further stop growing at all. The results allow us to conclude that information available to each new node in tournament dynamics restrains the emergence of new hierarchy levels and that it is the absolute amount of information, not relative, which governs such behavior.

Urinary NGAL, KIM-1 and L-FABP concentrations in antenatal hydronephrosis.

Science.gov (United States)

Noyan, Aytul; Parmaksiz, Gonul; Dursun, Hasan; Ezer, Semire Serin; Anarat, Ruksan; Cengiz, Nurcan

2015-10-01

The clinical tests currently in use for obstructive nephropathy (such as renal ultrasonography, differential radionuclide renal scans and urinary creatinine concentration data) are not efficient predictors of the subsequent clinical course. Novel and simple biomarkers are required which, if proven, could be clinically beneficial in determining if a patient is eligible for surgery or reno-protective therapy. More recently, the interest of clinicians has focused on the potential of urinary neutrophil gelatinase-associated lipocalin (uNGAL), urinary kidney injury molecule-1 (uKIM-1) and urinary liver-type fatty acid-binding proteins (uL-FABP) as biomarkers for renal function in children with hydronephrosis (HN). The purpose of this study was to investigate possible clinical applications of uNGAL, uKIM-1 and uL-FABP as beneficial non-invasive biomarkers to determine whether or not surgical intervention is required in children with HN. Renal ultrasonography and radionuclide renal scans were used as diagnostic tools to detect HN. Patients were divided into two groups based on the antero-posterior diameter of their renal pelvis and the presence of dysfunction. Group 1 included 26 children with severe HN (with dysfunction), and group 2 consisted of 36 children with mild HN (without dysfunction). Urine samples were collected from 62 children with HN and 20 healthy children. Hydronephrosis was more common in males than in females, with a male to female ratio of 9:1 in the study sample. The incidence of left kidney involvement (32 patients) was slightly higher than right kidney involvement (28 patients). Compared with controls and group 2, the ratio of uNGAL to creatinine was significantly higher in group 1 (p hydronephrosis and dysfunction had significantly increased uNGAL, and uNGAL/Cr concentrations. However, uKIM-1, uKIM-1/Cr, uL-FABP and uL-FABP/Cr concentrations were not significantly different when compared with controls. These results support the use of u

In praise of hierarchy.

Science.gov (United States)

Jaques, E

1990-01-01

Hierarchy has not had its day. After 3,000 years as the preferred structure for large organizations, managerial hierarchy is still the most natural and effective organizational form that a big company can employ. Now, as in the past, the key to organizational success is individual accountability, and hierarchy preserves unambiguous accountability for getting work done. Unfortunately, hierarchy is widely misunderstood and abused. Pay grades are confused with real layers of responsibility, for example, and incompetent bosses abound. As a result, many experts now urge us to adopt group-oriented or "flat" structures. But groups are never held accountable as groups for what they do or fail to do, and groups don't have careers. The proper use of hierarchy derives from the nature of work. As organizational tasks range from simple to very complex, there are sharp jumps in the level of difficulty and responsibility. Surprisingly, people in hundreds of companies in dozens of countries agree on where these jumps take place. They are tied to an objective measure-the time span of the longest task or program assigned to each managerial role-and they occur at 3 months, 1 year, 2 years, 5 years, 10 years, and 20 years. As the time span increases, so does the level of experience, knowledge, and mental stamina required to do the work. This increasing level of mental capacity lets companies put people in jobs they can do, it allows managers to add value to the work of their subordinates, it creates hierarchical layers acceptable to everyone in the organization, and it allows employees to be evaluated by people they accept as organizational superiors. Best of all, understanding hierarchy allows organizations to set up hierarchies with no more than seven layers-often fewer-and to know what the structure is good for and how it ought to perform.

A note on the KP hierarchy

International Nuclear Information System (INIS)

Depireux, D.A.

1992-01-01

In this paper, given the two boson representation of the conformal algebra W ∞ , the second Hamiltonian structure of the KP hierarchy, the author constructs a bi-Hamiltonian hierarchy for the two associated currents. The KP hierarchy appears as a composite of this new and simpler system. The bi-Hamiltonian structure of the new hierarchy gives naturally all the Hamiltonian structures of the KP system

Exact Solutions for Two Equation Hierarchies

International Nuclear Information System (INIS)

Song-Lin, Zhao; Da-Jun, Zhang; Jie, Ji

2010-01-01

Bilinear forms and double-Wronskian solutions are given for two hierarchies, the (2+1)-dimensional breaking Ablowitz–Kaup–Newell–Segur (AKNS) hierarchy and the negative order AKNS hierarchy. According to some choices of the coefficient matrix in the Wronskian condition equation set, we obtain some kinds of solutions for these two hierarchies, such as solitons, Jordan block solutions, rational solutions, complexitons and mixed solutions. (general)

Delivery of bone morphogenetic protein-2 and substance P using graphene oxide for bone regeneration

Directory of Open Access Journals (Sweden)

La WG

2014-05-01

Full Text Available Wan-Geun La,1 Min Jin,1 Saibom Park,1,2 Hee-Hun Yoon,1 Gun-Jae Jeong,1 Suk Ho Bhang,1 Hoyoung Park,1,2 Kookheon Char,1,2 Byung-Soo Kim1,31School of Chemical and Biological Engineering, Seoul National University, Seoul, Republic of Korea; 2The National Creative Research Initiative Center for Intelligent Hybrids, Seoul National University, Seoul, Republic of Korea; 3Institute of Bioengineering, Institute of Chemical Processes, Engineering Research Institute, Seoul National University, Seoul, Republic of KoreaAbstract: In this study, we demonstrate that graphene oxide (GO can be used for the delivery of bone morphogenetic protein-2 (BMP-2 and substance P (SP, and that this delivery promotes bone formation on titanium (Ti implants that are coated with GO. GO coating on Ti substrate enabled a sustained release of BMP-2. BMP-2 delivery using GO-coated Ti exhibited a higher alkaline phosphatase activity in bone-forming cells in vitro compared with bare Ti. SP, which is known to recruit mesenchymal stem cells (MSCs, was co-delivered using Ti or GO-coated Ti to further promote bone formation. SP induced the migration of MSCs in vitro. The dual delivery of BMP-2 and SP using GO-coated Ti showed the greatest new bone formation on Ti implanted in the mouse calvaria compared with other groups. This approach may be useful to improve osteointegration of Ti in dental or orthopedic implants.Keywords: bone morphogenetic protein-2, bone regeneration, graphene oxides, stem cell recruitment, substance P

Consumption-based Total Suspended Particulate Matter Emissions in Jing-Jin-Ji Area of China

Science.gov (United States)

Yang, S.; Chen, S.; Chen, B.

2014-12-01

The highly-industrialized regions in China have been facing a serious problem of haze mainly consisted of total suspended particulate matter (TSPM), which has attracted great attention from the public since it directly impairs human health and clinically increases the risks of various respiratory and pulmonary diseases. In this paper, we set up a multi-regional input-output (MRIO) model to analyze the transferring routes of TSPM emissions between regions through trades. TSPM emission from particulate source regions and sectors are identified by analyzing the embodied TSPM flows through monetary flow and carbon footprint. The track of TSPM from origin to end via consumption activities are also revealed by tracing the product supply chain associated with the TSPM emissions. Beijing-Tianjin-Hebei (Jing-Jin-Ji) as the most industrialized area of China is selected for a case study. The result shows that over 70% of TSPM emissions associated with goods consumed in Beijing and Tianjin occurred outside of their own administrative boundaries, implying that Beijing and Tianjin are net embodied TSPM importers. Meanwhile, 63% of the total TSPM emissions in Hebei Province are resulted from the outside demand, indicating Hebei is a net exporter. In addition, nearly half of TSPM emissions are the by-products related to electricity and heating supply and non-metal mineral products in Jing-Jin-Ji Area. Based on the model results, we provided new insights into establishing systemic strategies and identifying mitigation priorities to stem TSPM emissions in China. Keywords: total suspended particulate matter (TSPM); urban ecosystem modeling; multi-regional input-output (MRIO); China

Additional symmetries of supersymmetric KP hierarchies

International Nuclear Information System (INIS)

Stanciu, S.

1994-01-01

We investigate the additional symmetries of several supersymmetric KP hierarchies: the SKP hierarchy of Manin and Radul, the SKP 2 hierarchy, and the Jacobian SKP hierarchy. In all three cases we find that the algebra of symmetries is isomorphic to the algebra of superdifferential operators, or equivalently SW 1+∞ . These results seem to suggest that despite their realization depending on the dynamics, the additional symmetries are kinematical in nature. (orig.)

Kim C. Sturgess. Shakespeare and the American Nation.

Directory of Open Access Journals (Sweden)

Jean‑Louis Claret

2006-04-01

Full Text Available The front page of Kim C Sturgess’s recent book entitled Shakespeare and the American Nation is particularly mind‑teasing insofar as it represents the famous Droeshout engraving of the bard (it illustrated the front‑page of the 1623 edition of Shakespeare’s works standing out against a background that superimposes the head of the Statue of Liberty on the spangled banner. The starting point of Sturgess’s 234‑page demonstration endorsed by Cambridge University Press is a paradox that the Britis...

Visualising large hierarchies with Flextree

Science.gov (United States)

Song, Hongzhi; Curran, Edwin P.; Sterritt, Roy

2003-05-01

One of the main tasks in Information Visualisation research is creating visual tools to facilitate human understanding of large and complex information spaces. Hierarchies, being a good mechanism in organising such information, are ubiquitous. Although much research effort has been spent on finding useful representations for hierarchies, visualising large hierarchies is still a difficult topic. One of the difficulties is how to show both tructure and node content information in one view. Another is how to achieve multiple foci in a focus+context visualisation. This paper describes a novel hierarchy visualisation technique called FlexTree to address these problems. It contains some important features that have not been exploited so far. In this visualisation, a profile or contour unique to the hierarchy being visualised can be gained in a histogram-like layout. A normalised view of a common attribute of all nodes can be acquired, and selection of this attribute is controllable by the user. Multiple foci are consistently accessible within a global context through interaction. Furthermore it can handle a large hierarchy that contains several thousand nodes in a PC environment. In addition results from an informal evaluation are also presented.

On the robustness of Herlihy's hierarchy

Science.gov (United States)

Jayanti, Prasad

1993-01-01

A wait-free hierarchy maps object types to levels in Z(+) U (infinity) and has the following property: if a type T is at level N, and T' is an arbitrary type, then there is a wait-free implementation of an object of type T', for N processes, using only registers and objects of type T. The infinite hierarchy defined by Herlihy is an example of a wait-free hierarchy. A wait-free hierarchy is robust if it has the following property: if T is at level N, and S is a finite set of types belonging to levels N - 1 or lower, then there is no wait-free implementation of an object of type T, for N processes, using any number and any combination of objects belonging to the types in S. Robustness implies that there are no clever ways of combining weak shared objects to obtain stronger ones. Contrary to what many researchers believe, we prove that Herlihy's hierarchy is not robust. We then define some natural variants of Herlihy's hierarchy, which are also infinite wait-free hierarchies. With the exception of one, which is still open, these are not robust either. We conclude with the open question of whether non-trivial robust wait-free hierarchies exist.

The Analytical Hierarchy Process

DEFF Research Database (Denmark)

Barfod, Michael Bruhn

2007-01-01

The technical note gathers the theory behind the Analytical Hierarchy Process (AHP) and present its advantages and disadvantages in practical use.......The technical note gathers the theory behind the Analytical Hierarchy Process (AHP) and present its advantages and disadvantages in practical use....

Additional symmetries of supersymmetric KP hierarchies

International Nuclear Information System (INIS)

Stanciu, S.

1993-09-01

We investigate the additional symmetries of several supersymmetric KP hierarchies: The SKP hierarchy of Manin and Radul, the SKP 2 hierarchy, and the Jacobian SKP hierarchy. The main technical tool is the supersymmetric generalisation of a map originally due to Radul between the Lie algebra of superdifferential operators and the Lie algebra of vector fields on the space of supersymmetric Lax operators. In the case of the Manin-Radul SKP hierarchy we identify additional symmetries which form an algebra isomorphic to a subalgebra of superdifferential operators; whereas in the case of the Jacobian SKP, the (additional) symmetries are identified with the algebra itself. (orig.)

Gauge-symmetry hierarchies revisited

International Nuclear Information System (INIS)

Gildener, E.

1979-01-01

It was shown by the author in a previous paper that in each order of perturbation theory there is an upper bound on the range of validity of a gauge hierarchy. Thus constructing a large hierarchy requires a fine-tuning of the scalar-field parameters. It was stated that the possibility of an inherent bound on the hierarchy exists, but the question of the actual existence of such a bound was left completely open. Since then several authors have addressed this problem. Some of what the author asserted was misunderstood, and incorrect conclusions have been drawn from recent computations. It has been claimed that the existence of large hierarchies has been demonstrated. It is the purpose of this paper to refute this claim, to help clarify the situation, and to explain why the status of this problem has in fact not really changed in recent years (author)

The first clinical treatment with kilovoltage intrafraction monitoring (KIM): A real-time image guidance method

DEFF Research Database (Denmark)

Keall, Paul J.; Aun Ng, Jin; O'Brien, Ricky

2015-01-01

on September 16, 2014. Methods: KIM uses current and prior 2D x-ray images to estimate the 3D target position during cancer radiotherapy treatment delivery. KIM software was written to process kilovoltage (kV) images streamed from a standard C-arm linear accelerator with a gantry-mounted kV x-ray imaging...... system. A 120° pretreatment kV imaging arc was acquired to build the patient-specific 2D to 3D motion correlation. The kV imager was activated during the megavoltage (MV) treatment, a dual arc VMAT prostate treatment, to estimate the 3D prostate position in real-time. All necessary ethics, legal......, and regulatory requirements were met for this clinical study. The quality assurance processes were completed and peer reviewed. Results: During treatment, a prostate position offset of nearly 3 mm in the posterior direction was observed with KIM. This position offset did not trigger a gating event. After...

New supersymmetrizations of the generalized KDV hierarchies

International Nuclear Information System (INIS)

Figueroa-O'Farrill, J.M.; Stanciu, S.

1993-03-01

Recently we investigated a new supersymmetrization procedure for the KdV hierarchy inspired in some recent work on supersymmetric matrix models. We extend this procedure here for the generalized KdV hierarchies. The resulting supersymmetric hierarchies are generically nonlocal, expect for the case of Boussinesque which we treat in detail. The resulting supersymmetric hierarchy is integrable and bihamiltonian and contains the Boussinesque hierarchy as a subhierarchy. In a particular realization, we extend it by defining supersymmetric odd flows. We end with some comments on a slight modification of this supersymmetrization which yields local equations for any generalized KdV hierarchy. (orig.)

A Hierarchy Model of Income Distribution

OpenAIRE

Fix, Blair

2018-01-01

Based on worldly experience, most people would agree that firms are hierarchically organized, and that pay tends to increase as one moves up the hierarchy. But how this hierarchical structure affects income distribution has not been widely studied. To remedy this situation, this paper presents a new model of income distribution that explores the effects of social hierarchy. This ‘hierarchy model’ takes the limited available evidence on the structure of firm hierarchies and generalizes it to c...

Hierarchy is Detrimental for Human Cooperation.

Science.gov (United States)

Cronin, Katherine A; Acheson, Daniel J; Hernández, Penélope; Sánchez, Angel

2015-12-22

Studies of animal behavior consistently demonstrate that the social environment impacts cooperation, yet the effect of social dynamics has been largely excluded from studies of human cooperation. Here, we introduce a novel approach inspired by nonhuman primate research to address how social hierarchies impact human cooperation. Participants competed to earn hierarchy positions and then could cooperate with another individual in the hierarchy by investing in a common effort. Cooperation was achieved if the combined investments exceeded a threshold, and the higher ranked individual distributed the spoils unless control was contested by the partner. Compared to a condition lacking hierarchy, cooperation declined in the presence of a hierarchy due to a decrease in investment by lower ranked individuals. Furthermore, hierarchy was detrimental to cooperation regardless of whether it was earned or arbitrary. These findings mirror results from nonhuman primates and demonstrate that hierarchies are detrimental to cooperation. However, these results deviate from nonhuman primate findings by demonstrating that human behavior is responsive to changing hierarchical structures and suggests partnership dynamics that may improve cooperation. This work introduces a controlled way to investigate the social influences on human behavior, and demonstrates the evolutionary continuity of human behavior with other primate species.

Retribution as hierarchy regulation: Hierarchy preferences moderate the effect of offender socioeconomic status on support for retribution.

Science.gov (United States)

Redford, Liz; Ratliff, Kate A

2018-01-01

People punish others for various reasons, including deterring future crime, incapacitating the offender, and retribution, or payback. The current research focuses on retribution, testing whether support for retribution is motivated by the desire to maintain social hierarchies. If so, then the retributive tendencies of hierarchy enhancers or hierarchy attenuators should depend on whether offenders are relatively lower or higher in status, respectively. Three studies showed that hierarchy attenuators were more retributive against high-status offenders than for low-status offenders, that hierarchy enhancers showed a stronger orientation towards retributive justice, and that relationship was stronger for low-status, rather than high-status, criminal offenders. These findings clarify the purpose and function of retributive punishment. They also reveal how hierarchy-regulating motives underlie retribution, motives which, if allowed to influence judgements, may contribute to biased or ineffective justice systems. © 2017 The British Psychological Society.

People who live for quality

International Nuclear Information System (INIS)

1995-03-01

This book introduces the case of model of quality management. There are a lot of titles and people's example such as with dogged perseverance by Kang, Beom Sik in SK industry, come back to company which he submitted his resignation by Kim, Byeong Hui in Hyundai Heavy industries, I want to be the world best by Yeon, Sang Jin in Geum Ho industry, a good beginning is half the battle by Kwon, Bok Sik in KIA company, employee satisfaction is quality management by Hong, Sun Gyeom, in Dong Yang piston, and praying for all by Kim, Youn Ja in Lotte department store.

The diagnostic importance of the new marker KIM-1 in kidney damage

Directory of Open Access Journals (Sweden)

Zofia Marchewka

2013-07-01

Full Text Available In recent years, the rapid development of scientific research led to the introduction of strategies based on new markers that allow for estimation of the latent disease period before the clinical symptoms of actual kidney failure are revealed.The experimental tests carried out on animals and cell lines derived from the proximal tubule have made possible the detection of genes that are induced early after hypoxia [1].The protein products of these genes can be considered as useful markers for the diagnosis of renal failure. The induction of gene KIM-1 (called Kidney Injury Molecule-1 results in the formation of protein that can be considered as a diagnostic marker.This work describes the data on the structure, biological function and importance of determining the concentrations of KIM-1 in the diagnosis of drug-induced toxicity and kidney damage.

[The diagnostic importance of the new marker KIM-1 in kidney damage].

Science.gov (United States)

Marchewka, Zofia; Płonka, Joanna

2013-07-24

In recent years, the rapid development of scientific research led to the introduction of strategies based on new markers that allow for estimation of the latent disease period before the clinical symptoms of actual kidney failure are revealed. The experimental tests carried out on animals and cell lines derived from the proximal tubule have made possible the detection of genes that are induced early after hypoxia. The protein products of these genes can be considered as useful markers for the diagnosis of renal failure. The induction of gene KIM-1 (called Kidney Injury Molecule-1) results in the formation of protein that can be considered as a diagnostic marker. This work describes the data on the structure, biological function and importance of determining the concentrations of KIM-1 in the diagnosis of drug-induced toxicity and kidney damage.

Explorations of the extended ncKP hierarchy

International Nuclear Information System (INIS)

Dimakis, Aristophanes; Mueller-Hoissen, Folkert

2004-01-01

A recently obtained extension (xncKP) of the Moyal-deformed KP hierarchy (ncKP hierarchy) by a set of evolution equations in the Moyal-deformation parameters is further explored. Formulae are derived to compute these equations efficiently. Reductions of the xncKP hierarchy are treated, in particular to the extended ncKdV and ncBoussinesq hierarchies. Furthermore, a good part of the Sato formalism for the KP hierarchy is carried over to the generalized framework. In particular, the well-known bilinear identity theorem for the KP hierarchy, expressed in terms of the (formal) Baker-Akhiezer function, extends to the xncKP hierarchy. Moreover, it is demonstrated that N-soliton solutions of the ncKP equation are also solutions of the first few deformation equations. This is shown to be related to the existence of certain families of algebraic identities

Gauge equivalence between two-boson KP hierarchies

International Nuclear Information System (INIS)

Aratyn, H.

1994-01-01

In this paper it is explained the status of the two-boson KP hierarchy, which appears in this setting as an invariant subspace of the coadjoint orbit within the KP l=1 hierarchy. We will work with two main cases of two-boson KP hierarchies, one defined within KP l=1 hierarchy will be called Faa di Bruno KP hierarchy, while the second defined within KP hierarchy for a quadratic two-boson KP hierarchy. It will be established for them the gauge invariance playing the role of generalized Miura transformations. It is emphasized the symplectic character of equivalence of KP l=1 and KP. It is also made a point that the gauge equivalence established for two-boson systems is valid for an arbitrary n-th Poisson bracket structure and not only the first Poisson bracket structure. (author). 7 refs

Two New Multi-component BKP Hierarchies

International Nuclear Information System (INIS)

Wu Hongxia; Liu Xiaojun; Zeng Yunbo

2009-01-01

We firstly propose two kinds of new multi-component BKP (mcBKP) hierarchy based on the eigenfunction symmetry reduction and nonstandard reduction, respectively. The first one contains two types of BKP equation with self-consistent sources whose Lax representations are presented. The two mcBKP hierarchies both admit reductions to the k-constrained BKP hierarchy and to integrable (1+1)-dimensional hierarchy with self-consistent sources, which include two types of SK equation with self-consistent sources and of bi-directional SK equations with self-consistent sources.

Isoeugenol monooxygenase and its putative regulatory gene are located in the eugenol metabolic gene cluster in Pseudomonas nitroreducens Jin1.

Science.gov (United States)

Ryu, Ji-Young; Seo, Jiyoung; Unno, Tatsuya; Ahn, Joong-Hoon; Yan, Tao; Sadowsky, Michael J; Hur, Hor-Gil

2010-03-01

The plant-derived phenylpropanoids eugenol and isoeugenol have been proposed as useful precursors for the production of natural vanillin. Genes involved in the metabolism of eugenol and isoeugenol were clustered in region of about a 30 kb of Pseudomonas nitroreducens Jin1. Two of the 23 ORFs in this region, ORFs 26 (iemR) and 27 (iem), were predicted to be involved in the conversion of isoeugenol to vanillin. The deduced amino acid sequence of isoeugenol monooxygenase (Iem) of strain Jin1 had 81.4% identity to isoeugenol monooxygenase from Pseudomonas putida IE27, which also transforms isoeugenol to vanillin. Iem was expressed in E. coli BL21(DE3) and was found to lead to isoeugenol to vanillin transformation. Deletion and cloning analyses indicated that the gene iemR, located upstream of iem, is required for expression of iem in the presence of isoeugenol, suggesting it to be the iem regulatory gene. Reverse transcription, real-time PCR analyses indicated that the genes involved in the metabolism of eugenol and isoeugenol were differently induced by isoeugenol, eugenol, and vanillin.

Spotlight on nano-theranostics in South Korea: applications in diagnostics and treatment of diseases

Directory of Open Access Journals (Sweden)

Lee S

2015-08-01

Full Text Available Sangwha Lee,1,* Jongsung Kim,1,* Chung Wung Bark,2 Bonghee Lee,3 Heongkyu Ju,4 Se Chan Kang,5 TaeYoung Kim,6 Moon Il Kim,6 Young Tag Ko,3 Jeong-Seok Nam,3 Hyon Hee Yoon,1 Kyu-Sik Yun,1,6 Young Soo Yoon,1 Seong Soo A An,1,6 John Hulme6 1BioNano Sensor Research Center, 2Department of Electrical Engineering, Gachon University, Seongnam-si, 3Lee Gil Ya Cancer and Diabetes Institute, Gachon University, Incheon, 4Department of Nano-Physics, 5Department of Life Science, Gachon University, 6Department of BioNano Technology, Gachon BioNano Research Institute, Seongnam-si, South Korea *These authors contributed equally to this work Abstract: From the synergistic integration and the multidisciplinary strengths of the BioNano Sensor Research Center, Gachon Bionano Research Institute, and Lee GilYa Cancer and Diabetes Institute, researchers, students, and faculties at Gachon University in collaboration with other institutions in Korea, Australia, France, America, and Japan have come together to produce a special issue on the diverse applications of nano-theranostics in nanomedicine. This special issue will showcase new research conducted by various scientific groups in Gyonggi-do and Songdo/Incheon, South Korea. The objectives of this special issue are as follows: 1 to bring together and demonstrate some of the latest research results in the field, 2 to introduce new multifunctional nanomaterials and their applications in imaging and detection methods, and 3 to stimulate collaborative interdisciplinary research at both national and international levels in nanomedicine. Keywords: cancer, imaging and therapeutics, antibacterial, disease, neurodegenerative

Generalized W-algebras and integrable hierarchies

International Nuclear Information System (INIS)

Burroughs, N.; De Groot, M.; Hollowood, T.; Miramontes, L.

1992-01-01

We report on generalizations of the KdV-type integrable hierarchies of Drinfel'd and Sokolov. These hierarchies lead to the existence of new classical W-algebras, which arise as the second hamiltonian structure of the hierarchies. In particular, we present a construction of the W n (l) -algebras. (orig.)

Tissue distribution and excretion kinetics of orally administered silica nanoparticles in rats

Directory of Open Access Journals (Sweden)

Lee JA

2014-12-01

Full Text Available Jeong-A Lee,1 Mi-Kyung Kim,1 Hee-Jeong Paek,1 Yu-Ri Kim,2 Meyoung-Kon Kim,2 Jong-Kwon Lee,3 Jayoung Jeong,3 Soo-Jin Choi1 1Department of Food Science and Technology, Seoul Women’s University, Seoul, Republic of Korea; 2Department of Biochemistry and Molecular Biology, Korea University Medical School and College, Seoul, Republic of Korea; 3Toxicological Research Division, National Institute of Food and Drug Safety Evaluation, Chungchungbuk–do, Republic of Korea Purpose: The effects of particle size on the tissue distribution and excretion kinetics of silica nanoparticles and their biological fates were investigated following a single oral administration to male and female rats. Methods: Silica nanoparticles of two different sizes (20 nm and 100 nm were orally administered to male and female rats, respectively. Tissue distribution kinetics, excretion profiles, and fates in tissues were analyzed using elemental analysis and transmission electron microscopy. Results: The differently sized silica nanoparticles mainly distributed to kidneys and liver for 3 days post-administration and, to some extent, to lungs and spleen for 2 days post-administration, regardless of particle size or sex. Transmission electron microscopy and energy dispersive spectroscopy studies in tissues demonstrated almost intact particles in liver, but partially decomposed particles with an irregular morphology were found in kidneys, especially in rats that had been administered 20 nm nanoparticles. Size-dependent excretion kinetics were apparent and the smaller 20 nm particles were found to be more rapidly eliminated than the larger 100 nm particles. Elimination profiles showed 7%–8% of silica nanoparticles were excreted via urine, but most nanoparticles were excreted via feces, regardless of particle size or sex. Conclusion: The kidneys, liver, lungs, and spleen were found to be the target organs of orally-administered silica nanoparticles in rats, and this organ

Hierarchy is Detrimental for Human Cooperation

Science.gov (United States)

Cronin, Katherine A.; Acheson, Daniel J.; Hernández, Penélope; Sánchez, Angel

2015-01-01

Studies of animal behavior consistently demonstrate that the social environment impacts cooperation, yet the effect of social dynamics has been largely excluded from studies of human cooperation. Here, we introduce a novel approach inspired by nonhuman primate research to address how social hierarchies impact human cooperation. Participants competed to earn hierarchy positions and then could cooperate with another individual in the hierarchy by investing in a common effort. Cooperation was achieved if the combined investments exceeded a threshold, and the higher ranked individual distributed the spoils unless control was contested by the partner. Compared to a condition lacking hierarchy, cooperation declined in the presence of a hierarchy due to a decrease in investment by lower ranked individuals. Furthermore, hierarchy was detrimental to cooperation regardless of whether it was earned or arbitrary. These findings mirror results from nonhuman primates and demonstrate that hierarchies are detrimental to cooperation. However, these results deviate from nonhuman primate findings by demonstrating that human behavior is responsive to changing hierarchical structures and suggests partnership dynamics that may improve cooperation. This work introduces a controlled way to investigate the social influences on human behavior, and demonstrates the evolutionary continuity of human behavior with other primate species. PMID:26692287

BBGKY hierarchy and dynamics of correlations

International Nuclear Information System (INIS)

Polishchuk, D.O.

2010-01-01

We derive the BBGKY hierarchy for the Fermi and Bose many-particle systems, using the von Neumann hierarchy for the correlation operators. The solution of the Cauchy problem of the formulated hierarchy in the case of an n-body interaction potential is constructed in the space of sequences of trace-class operators.

Kim Wŏn-haeng’s Intellectual Influences on Hong Tae-yong: The Case of Relations between

Directory of Open Access Journals (Sweden)

Login Lok-yin Law

2015-08-01

Full Text Available In the 18th century Chosŏn (1392-1910, some scholars, such as Hong Tae-yong (1731-1783 advocated that Chosŏn should learn the advantages of the Qing (1644-1912 society to reform the social structure and government of Chosŏn. The school of these advocates has been known as Pukhak by historians. The intellectual factors of the school of Pukhak’s formation and development have been overlooked by the academia of Chosŏn intellectual history. In fact, Pukhak was closely related to the idea of the school of Nakhak which believed that nature of things was equivalent to humans. Kim Wŏn-haeng, was one of the supporters of Nakhak and Hong Tae-yong was one of the students of Kim. Hong’s thought and writing exposed that his thought was profoundly influenced by Kim Wŏn-haeng. Hong was deemed to be the first prominent scholar of the Pukhak School during the 18th century Chosŏn. Hong and other scholars of Pukhak advocated learning the new knowledge from Qing China even though it was a barbarian society. Therefore, this paper will investigate the intellectual relationships between Hong Tae-yong and Kim Wŏn-haeng to reveal how intellectuals of Nakhak shaped the formation of Pukhak School and exposed the idea of learning from Qing China.

Affine Lie algebraic origin of constrained KP hierarchies

International Nuclear Information System (INIS)

Aratyn, H.; Gomes, J.F.; Zimerman, A.H.

1994-07-01

It is presented an affine sl(n+1) algebraic construction of the basic constrained KP hierarchy. This hierarchy is analyzed using two approaches, namely linear matrix eigenvalue problem on hermitian symmetric space and constrained KP Lax formulation and we show that these approaches are equivalent. The model is recognized to be generalized non-linear Schroedinger (GNLS) hierarchy and it is used as a building block for a new class of constrained KP hierarchies. These constrained KP hierarchies are connected via similarity-Backlund transformations and interpolate between GNLS and multi-boson KP-Toda hierarchies. The construction uncovers origin of the Toda lattice structure behind the latter hierarchy. (author). 23 refs

Dual functions of silver nanoparticles in F9 teratocarcinoma stem cells, a suitable model for evaluating cytotoxicity- and differentiation-mediated cancer therapy

OpenAIRE

Han, Jae Woong; Gurunathan, Sangiliyandi; Choi, Yun-Jung; Kim, Jin-Hoi

2017-01-01

Jae Woong Han, Sangiliyandi Gurunathan, Yun-Jung Choi, Jin-Hoi Kim Department of Stem Cell and Regenerative Biotechnology, Humanized Pig Research Center (SRC), Konkuk University, Seoul, Republic of Korea Background: Silver nanoparticles (AgNPs) exhibit strong antibacterial and anticancer activity owing to their large surface-to-volume ratios and crystallographic surface structure. Owing to their various applications, understanding the mechanisms of action, biological interactions, potential...

Models of neutrino masses: Anarchy versus hierarchy

International Nuclear Information System (INIS)

Altarelli, Guido; Feruglio, Ferruccio; Masina, Isabella

2003-01-01

We present a quantitative study of the ability of models with different levels of hierarchy to reproduce the solar neutrino solutions, in particular the LA solution. As a flexible testing ground we consider models based on SU(5)xU(1) F . In this context, we have made statistical simulations of models with different patterns from anarchy to various types of hierarchy: normal hierarchical models with and without automatic suppression of the 23 (sub)determinant and inverse hierarchy models. We find that, not only for the LOW or VO solutions, but even in the LA case, the hierarchical models have a significantly better success rate than those based on anarchy. The normal hierarchy and the inverse hierarchy models have comparable performances in models with see-saw dominance, while the inverse hierarchy models are particularly good in the no see-saw versions. As a possible distinction between these categories of models, the inverse hierarchy models favour a maximal solar mixing angle and their rate of success drops dramatically as the mixing angle decreases, while normal hierarchy models are far more stable in this respect. (author)

Multiple Hierarchies and Organizational Control

Science.gov (United States)

Evans, Peter B.

1975-01-01

Uses a control-loss model to explore the effects of multiple channels in formal organizations, and presents an argument for the superior control properties of dual hierarchies. Two variant forms of multiple hierarchies are considered. (Author)

Iklan Sebagai Media Kritik Sosial (Pesan Simbolik Iklan Kretek Djarum 76 Seri Jin

Directory of Open Access Journals (Sweden)

Firdaus Azwar Ersyad

2016-04-01

Full Text Available The presence of television advertising is a prayer one way to manufacturer for review introduce and selling products for society. Regarding the regulation of advertising especially cigarettes and tobacco products manufacturer in order to encourage creative hearts introducing more on audience their product . As a result , the creativity in the hearts smoking ads aimed lifting product image so not operate direct products display .Singer study originated from the interest against visualization advertisements Djarum 76 series java jin  has its own peculiarities compared to other products . Zoom the one consolation is not revealed that an advertiser is selling products . Views are interpreted by different groups various ad viewers, but the views can be grouped into some basic ideas

[Status of diagnosis and treatment devices of acupuncture based on SooPAT and bibliometrics in China].

Science.gov (United States)

Bai, Lin; Ren, Yulan; Guo, Taipin; Chen, Lin; Zhou, Yumei; Feng, Shuwei; Li, Ji; Liang, Fanrong

2016-11-12

To perform a bibliometrics analysis on patent literature regarding diagnosis and treatment devices of acupuncture in China, aiming to provide references for the development of diagnosis and treatment devices of acupuncture. Based on SooPAT, a patent database, the patent literature regarding diagnosis and treatment devices of acupuncture in China was collected. With bibliometrics methods, the annual distribution of type, quantity, classification and content of diagnosis and treatment devices of acupuncture were analyzed. The number of acupuncture diagnosis and treatment devices reached its peak in 2012 and 2013 in China. The A61N in patent and utility model patent were the most, which were mainly related to electrotherapy, magnetic therapy, radioactive therapy and ultrasound therapy, etc. The main content was acupuncture treatment devices and meridian treatment devices. The 24-01 in design patent was the most, involving fixation devices used by doctors, hospitals and laboratories, etc. Currently the majority of diagnosis and treatment devices of acupuncture is therapeutic apparatus, while the acupuncture diagnosis devices are needed.

Solutions of the bigraded Toda hierarchy

International Nuclear Information System (INIS)

Li Chuanzhong

2011-01-01

The (N, M)-bigraded Toda hierarchy is an extension of the original Toda lattice hierarchy. The pair of numbers (N, M) represents the band structure of the Lax matrix which has N upper and M lower diagonals, and the original one is referred to as the (1, 1)-bigraded Toda hierarchy. Because of this band structure, one can introduce M + N - 1 commuting flows which give a parametrization of a small phase space for a topological field theory. In this paper, first we show that there exists a natural symmetry between the (N, M)- and (M, N)-bigraded Toda hierarchies. We then derive the Hirota bilinear form for those commuting flows, which consist of two-dimensional Toda hierarchy, the discrete KP hierarchy and its Baecklund transformations. We also discuss the solution structure of the (N, M)-bigraded Toda equation in terms of the moment matrix defined via the wave operators associated with the Lax operator and construct some of the explicit solutions. In particular, we give the rational solutions which are expressed by the products of the Schur polynomials corresponding to the non-rectangular Young diagrams.

Language and Family Dispersion: North Korean Linguist Kim Su-gyŏng and the Korean War

Directory of Open Access Journals (Sweden)

Ryuta Itagaki

2017-03-01

Full Text Available This article analyzes the unpublished memoir of Kim Su-gyŏng (1918–2000, a linguist who was active in North Korea from the mid-1940s until the late 1960s, and situates his account of his experience of the Korean War within the context of his linguistic essays and correspondence. In doing so, the article considers the role that the personal and the social play in language, utilizing Saussure’s theoretical framework, with which Kim himself was well versed. Kim wrote his memoirs in the 1990s to his family, from whom he had become separated during the Korean War and who now lived in Toronto. In this text, he writes in “personal” language that reveals his uncertainty and his feelings for his family, but then immediately negates these feelings through the use of “social” language, which resonates with his interpretation of the linguistic thesis that Josef Stalin developed during the Korean War on language and national identity. For Kim, the relationship between language and nation was not at all self-evident, but something that he idealized in response to the dispersal of his family. By offering a reflexive reading of a memoir written by a North Korean linguist, this article makes a breakthrough in the investigation of North Korean wartime academic history, which has not risen above the level of analyzing articles in the field of linguistics that were published at the time.

Biokinetics of zinc oxide nanoparticles: toxicokinetics, biological fates, and protein interaction

Directory of Open Access Journals (Sweden)

Choi SJ

2014-12-01

Full Text Available Soo-Jin Choi,1 Jin-Ho Choy2 1Department of Food Science and Technology, Seoul Women's University, 2Center for Intelligent Nano Bio Materials (CINBM, Department of Bioinspired Science and Department of Chemistry and Nanoscience, Ewha Womans University, Seoul, South Korea Abstract: Biokinetic studies of zinc oxide (ZnO nanoparticles involve systematic and quantitative analyses of absorption, distribution, metabolism, and excretion in plasma and tissues of whole animals after exposure. A full understanding of the biokinetics provides basic information about nanoparticle entry into systemic circulation, target organs of accumulation and toxicity, and elimination time, which is important for predicting the long-term toxic potential of nanoparticles. Biokinetic behaviors can be dependent on physicochemical properties, dissolution property in biological fluids, and nanoparticle–protein interaction. Moreover, the determination of biological fates of ZnO nanoparticles in the systemic circulation and tissues is critical in interpreting biokinetic behaviors and predicting toxicity potential as well as mechanism. This review focuses on physicochemical factors affecting the biokinetics of ZnO nanoparticles, in concert with understanding bioavailable fates and their interaction with proteins. Keywords: ZnO nanoparticles, biokinetics, distribution, excretion, fate, interaction

Completing the land resource hierarchy

Science.gov (United States)

The Land Resource Hierarchy of the NRCS is a hierarchal landscape classification consisting of resource areas which represent both conceptual and spatially discrete landscape units stratifying agency programs and practices. The Land Resource Hierarchy (LRH) scales from discrete points (soil pedon an...

Understanding internal backgrounds in NaI(Tl) crystals toward a 200 kg array for the KIMS-NaI experiment

Energy Technology Data Exchange (ETDEWEB)

Adhikari, P.; Adhikari, G.; Oh, S.Y. [Sejong University, Department of Physics, Seoul (Korea, Republic of); Choi, S.; Joo, H.W.; Kim, K.W.; Kim, S.K. [Seoul National University, Department of Physics and Astronomy, Seoul (Korea, Republic of); Ha, C.; Jeon, E.J.; Kang, W.G.; Kim, H.O.; Kim, N.Y.; Lee, H.S.; Lee, J.H.; Lee, M.H.; Leonard, D.S.; Li, J.; Olsen, S.L.; Park, H.K.; Park, K.S.; So, J.H.; Yoon, Y.S. [Institute for Basic Science, Center for Underground Physics, Daejeon (Korea, Republic of); Hahn, I.S. [Ewha Womans University, Department of Science Education, Seoul (Korea, Republic of); Kim, H.J. [Kyungpook National University, Department of Physics, Daegu (Korea, Republic of); Kim, Y.D. [Sejong University, Department of Physics, Seoul (Korea, Republic of); Institute for Basic Science, Center for Underground Physics, Daejeon (Korea, Republic of); Kim, Y.H. [Institute for Basic Science, Center for Underground Physics, Daejeon (Korea, Republic of); Korea Research Institute of Standards and Science, Daejeon (Korea, Republic of); Park, H.S. [Korea Research Institute of Standards and Science, Daejeon (Korea, Republic of)

2016-04-15

The Korea Invisible Mass Search (KIMS) collaboration has developed low-background NaI(Tl) crystals that are suitable for the direct detection of WIMP dark matter. Building on experience accumulated during the KIMS-CsI programs, the KIMS-NaI experiment will consist of a 200 kg NaI(Tl) crystal array surrounded by layers of shielding structures and will be operated at the Yangyang underground laboratory. The goal is to provide an unambiguous test of the DAMA/LIBRA annual modulation signature. Measurements of six prototype crystals show progress in the reduction of internal contamination from radioisotopes. Based on our understanding of these measurements, we expect to achieve a background level in the final detector configuration that is less than 1 count/day/keV/kg for recoil energies around 2 keV. The annual modulation sensitivity for the KIMS-NaI experiment shows that an unambiguous 7σ test of the DAMA/LIBRA signature would be possible with a 600 kg year exposure with this system. (orig.)

Generalized NLS hierarchies from rational W algebras

International Nuclear Information System (INIS)

Toppan, F.

1993-11-01

Finite rational W algebras are very natural structures appearing in coset constructions when a Kac-Moody subalgebra is factored out. The problem of relating these algebras to integrable hierarchies of equations is studied by showing how to associate to a rational W algebra its corresponding hierarchy. Two examples are worked out, the sl(2)/U(1) coset, leading to the Non-Linear Schroedinger hierarchy, and the U(1) coset of the Polyakov-Bershadsky W algebra, leading to a 3-field representation of the KP hierarchy already encountered in the literature. In such examples a rational algebra appears as algebra of constraints when reducing a KP hierarchy to a finite field representation. This fact arises the natural question whether rational algebras are always associated to such reductions and whether a classification of rational algebras can lead to a classification of the integrable hierarchies. (author). 19 refs

Hierarchy, Dominance, and Deliberation: Egalitarian Values Require Mental Effort.

Science.gov (United States)

Van Berkel, Laura; Crandall, Christian S; Eidelman, Scott; Blanchar, John C

2015-09-01

Hierarchy and dominance are ubiquitous. Because social hierarchy is early learned and highly rehearsed, the value of hierarchy enjoys relative ease over competing egalitarian values. In six studies, we interfere with deliberate thinking and measure endorsement of hierarchy and egalitarianism. In Study 1, bar patrons' blood alcohol content was correlated with hierarchy preference. In Study 2, cognitive load increased the authority/hierarchy moral foundation. In Study 3, low-effort thought instructions increased hierarchy endorsement and reduced equality endorsement. In Study 4, ego depletion increased hierarchy endorsement and caused a trend toward reduced equality endorsement. In Study 5, low-effort thought instructions increased endorsement of hierarchical attitudes among those with a sense of low personal power. In Study 6, participants' thinking quickly allocated more resources to high-status groups. Across five operationalizations of impaired deliberative thought, hierarchy endorsement increased and egalitarianism receded. These data suggest hierarchy may persist in part because it has a psychological advantage. © 2015 by the Society for Personality and Social Psychology, Inc.

The gauge hierarchy problem

International Nuclear Information System (INIS)

Natale, A.A.; Shellard, R.C.

1981-01-01

The problem of gauge hierarchy in Grand Unified Theories using a toy model with O(N) symmetry is discussed. It is shown that there is no escape to the unnatural adjustment of coupling constants, made only after the computation of several orders in perturbation theory is performed. The propositions of some authors on ways to overcome the gauge hierarchy problem are commented. (Author) [pt

Hierarchy is Detrimental for Human Cooperation

OpenAIRE

Cronin, Katherine A.; Acheson, Daniel J.; Hernández, Penélope; Sánchez, Angel

2016-01-01

Studies of animal behavior consistently demonstrate that the social environment impacts cooperation, yet the effect of social dynamics has been largely excluded from studies of human cooperation. Here, we introduce a novel approach inspired by nonhuman primate research to address how social hierarchies impact human cooperation. Participants competed to earn hierarchy positions and then could cooperate with another individual in the hierarchy by investing in a common effort. Cooperation was ac...

Oxidative stress-mediated antibacterial activity of graphene oxide and reduced graphene oxide in Pseudomonas aeruginosa

OpenAIRE

Gurunathan, Sangiliyandi; Han,Jae Woong; Abdal Daye,Ahmed; Eppakayala,Vasuki; Kim,Jin-Hoi

2012-01-01

Sangiliyandi Gurunathan, Jae Woong Han, Ahmed Abdal Dayem, Vasuki Eppakayala, Jin-Hoi KimDepartment of Animal Biotechnology, Konkuk University, Seoul, South KoreaBackground: Graphene holds great promise for potential use in next-generation electronic and photonic devices due to its unique high carrier mobility, good optical transparency, large surface area, and biocompatibility. The aim of this study was to investigate the antibacterial effects of graphene oxide (GO) and reduced graphene oxid...

The multicomponent 2D Toda hierarchy: dispersionless limit

International Nuclear Information System (INIS)

Mañas, Manuel; Alonso, Luis Martínez

2009-01-01

The factorization problem of the multi-component 2D Toda hierarchy is used to analyze the dispersionless limit of this hierarchy. A dispersive version of the Whitham hierarchy defined in terms of scalar Lax and Orlov–Schulman operators is introduced and the corresponding additional symmetries and string equations are discussed. Then, it is shown how KP and Toda pictures of the dispersionless Whitham hierarchy emerge in the dispersionless limit. Moreover, the additional symmetries and string equations for the dispersive Whitham hierarchy are studied in this limit

On the nesting of Painlevé hierarchies: A Hamiltonian approach

International Nuclear Information System (INIS)

Pickering, A.

2012-01-01

Highlights: ► Explanation of nesting of Painlevé hierarchies in terms of Hamiltonian structures. ► Approach generally phrased and applicable to continuous and discrete systems. ► Importance of related integrable hierarchies in understanding Painlevé hierarchies. - Abstract: We consider the phenomenon whereby two different Painlevé hierarchies, related to the same hierarchy of completely integrable equations, are such that solutions of one member of one of the Painlevé hierarchies are also solutions of a higher-order member of the other Painlevé hierarchy. An explanation is given in terms of the Hamiltonian structures of the related underlying completely integrable hierarchies, and is sufficiently generally formulated so as to be applicable equally to both continuous and discrete Painlevé hierarchies. Special integrals of a further Painlevé hierarchy related by Bäcklund transformation to the other Painlevé hierarchy mentioned above can also be constructed. Examples of the application of this approach to Painlevé hierarchies related to the Korteweg–de Vries, dispersive water wave, Toda and Volterra integrable hierarchies are considered. Our results provide further evidence of the importance of the underlying structures of related completely integrable hierarchies in understanding the properties of Painlevé hierarchies.

Height and sex is strongly associated with radial augmentation index in Korean patients with never-treated hypertension

Directory of Open Access Journals (Sweden)

Ahn KT

2016-04-01

Full Text Available Kye Taek Ahn, Kwang-In Park, Mi Joo Kim, Jin Kyung Oh, Ji Hye Han, Hee Jin Kwon, Seon-Ah Jin, Jun-Hyung Kim, Jae-Hyeong Park, Jae-Hwan Lee, Si Wan Choi, In-Whan Seong, Jin-Ok Jeong Department of Internal Medicine, Division of Cardiology, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Republic of Korea Objectives: Central hemodynamics may better represent the load imposed on the coronary and cerebral arteries and thereby bear a stronger relationship to cardiovascular outcomes. Methods: Patients who had confirmed hypertension as assessed by daytime 24-hour ambulatory blood pressure monitoring (≥135/85 mmHg were enrolled. Central blood pressure and radial augmentation index (AIx corrected for a heart rate of 75 bpm (radial AIx 75 were measured for all patients. We evaluated the association of age, height, and sex with central hemodynamics in patients with never-treated hypertension. Results: A total of 203 patients were enrolled, of whom men numbered 101 (49.7%. The median height of all patients was 162 cm, and mean age was 53.2 years. In the Pearson correlation analysis, regardless of sex difference (R=-0.627 for height, R=0.035 for age, P-value =0.005, a stronger relationship was observed between height and radial AIx 75 than between age and radial AIx 75. In the multiple regression analysis, the sex difference and height were strongly associated with elevated radial AIx 75 in all patients (adjusted R2=0.428, β=6.237, 95% confidence interval [CI] for women 1.480–10.995, P-value =0.011 and β=-0.632, 95% CI for height -0.929 to -0.335, P-value =0.009, respectively. Conclusion: In patients with never-treated hypertension, female sex and shorter height are the important risk factors of elevated radial AIx 75. Keywords: hypertension, augmentation index, height, sex

Hierarchies in Coloured Petri Nets

DEFF Research Database (Denmark)

Huber, Peter; Jensen, Kurt; Shapiro, Robert M.

1991-01-01

constructs, and it illustrates them by means of two examples. The hierarchy constructs can be used for theoretical considerations, but their main use is to describe and analyse large real-world systems. All of the hierarchy constructs are supported by the editing and analysis facilities in the CPN Palette...

Maslow's Hierarchy of Needs Revisited.

Science.gov (United States)

Frame, Douglas

1996-01-01

Reviews Maslow's hierarchy of needs and characterization of the self-actualizing personality, suggesting that since few people meet his self-actualization criteria, an educational system designed to produce such personalities may fail, with teachers attending only to the hierarchy's lower stages (self-esteem and self-actualization) which dilutes…

BANGUNAN TINGGI MULTI FUNGSI SEBAGAI SINTESIS ARSITEKTUR DAN STRUKTUR Studi Analisis Jin Mao Tower Grand Hyatt Shanghai

Directory of Open Access Journals (Sweden)

Jimmy Priatman

2005-01-01

Full Text Available More than two decades, after the emerging of post- modern architecture, the split between construction technology and cultural expression in architecture appeared to become wider and wider. With the exception of a few "high-tech" buildings, the unity of art and applied science (technology in design seems facing challenges. It is interesting to see how fast and unexpectedly the situation has changed. Many factors and people played a role in this reversal, many new buildings demonstrate that utilitarian artifacts do not have to be oppressive to creativity but can evoke new innovation. One of the most significant contributors was JIN MAO TOWER at Shanghai, China. The paper analyses this building as a genuine synthesis of rational intelligence with art poetry that is still possible. Abstract in Bahasa Indonesia : Lebih dari dua dekade setelah timbulnya arsitektur pasca modern, pemisahan antara tekknologi konstruksi dan ekspresi kultural dalam arsitektur menjadi semakin lebar. Dengan perkecualian beberapa gedung "high-tech", kesatuan antara seni dan teknologi dalam tahap desain terlihat menghadapi tantangan tantangan. Tetapi menarik untuk diamati bahwa situasi telah berubah. Banyak faktor dan tokoh tokoh arsitek memegang peranan penting dalam perubahan ini, banyak bangunan bangunan baru mendemontrasikan bahwa artefak fungsionil tidak bearti menindas kreativitas namun dapat membangkitkan inovasi baru. Salah satu kontributor yang sangat penting adalah JIN MAO TOWER di Shanghai-China. Makalah ini membahas bangunan tersebut sebagai sintesis orijinal yang masih memungkinkan antara kecerdasan rasional dengan puisi seni arsitektur. Kata kunci: Sintesis.

Delegation Within Hierarchies

DEFF Research Database (Denmark)

Dobrajska, Magdalena; Billinger, Stephan; Karim, Samina

2015-01-01

We investigate trade-offs associated with delegating authority over multiple interrelated decisions in a complex task structure. The empirical setting is a business process of a global Fortune 50 firm. The firm decentralized its organization and redefined decision authority across organizational......-relevant knowledge, the matching of required knowledge and managers’ expertise, and information processing intensity affect (a) the occurrence of delegation and, (b) if delegation occurs, how far down the organizational hierarchy authority is delegated. We discuss how these findings complement existing theories...... on delegation by providing insights into when and how interrelated decisions are delegated across multiple levels of an organizational hierarchy....

Rethinking the waste hierarchy

Energy Technology Data Exchange (ETDEWEB)

Rasmussen, C; Vigsoe, D [eds.

2005-03-01

There is an increasing need to couple environmental and economic considerations within waste management. Consumers and companies alike generate ever more waste. The waste-policy challenges of the future lie in decoupling growth in waste generation from growth in consumption, and in setting priorities for the waste management. This report discusses the criteria for deciding priorities for waste management methods, and questions the current principles of EU waste policies. The basis for the discussion is the so-called waste hierarchy which has dominated the waste policy in the EU since the mid-1970s. The waste hierarchy ranks possible methods of waste management. According to the waste hierarchy, the very best solution is to reduce the amount of waste. After that, reuse is preferred to recycling which, in turn, is preferred to incineration. Disposal at a landfill is the least favourable solution. (BA)

Hierarchy stability for spontaneously broken theories

Energy Technology Data Exchange (ETDEWEB)

Galvan, J B; Perez-Mercader, J; Sanchez, F J

1987-04-16

By using Weisberger's method for the integration of heavy degrees of freedom in multiscale theories, we show that tree level hierarchies are not destabilized byquantum corrections in a two-scale, two scalar field theory model where the heavy sector undergoes spontaneous symmetry breaking. We see explicitly the role played by the one-loop heavy log corrections to the effective parameters in maintaining the original tree level hierarchy and in keeping the theory free of hierarchy problems.

Hierarchy stability for spontaneously broken theories

International Nuclear Information System (INIS)

Galvan, J.B.; Perez-Mercader, J.; Sanchez, F.J.

1987-01-01

By using Weisberger's method for the integration of heavy degrees of freedom in multiscale theories, we show that tree level hierarchies are not destabilized byquantum corrections in a two-scale, two scalar field theory model where the heavy sector undergoes spontaneous symmetry breaking. We see explicitly the role played by the one-loop heavy log corrections to the effective parameters in maintaining the original tree level hierarchy and in keeping the theory free of hierarchy problems. (orig.)

Dominance Hierarchies in Young Children

Science.gov (United States)

Edelman, Murray S.; Omark, Donald R.

1973-01-01

This study uses the ethological approach of seeking species characteristics and phylogenetic continuities in an investigation of human behavior. Among primates a striking consistency is the presence of some form of dominance hierarchy in many species. The present study examines peer group dominance hierarchies as they are perceived by children in…

PINGU sensitivity to neutrino mass hierarchy

International Nuclear Information System (INIS)

Groß, Andreas

2014-01-01

Determination of the neutrino mass hierarchy (NMH) is among the most fundamental questions in particle physics. Recent measurements of 1) a large mixing angle between the first and the third neutrino mass eigenstates and 2) the first observation of atmospheric neutrino oscillations at tens of GeV with neutrino telescopes, open the intriguing new possibility to exploit matter effects in neutrino oscillation to determine the neutrino mass hierarchy. A further extension of IceCube/DeepCore called PINGU (Precision IceCube Next Generation Upgrade) has been recently envisioned with the ultimate goal to measure neutrino mass hierarchy. PINGU would consist of additional IceCube-like strings of detectors deployed in the deepest and cleanest ice in the center of IceCube. More densely deployed instrumentation would provide a threshold substantially below 10 GeV and enhance the sensitivity to the mass hierarchy signal in atmospheric neutrinos. Here we discuss an estimate of the PINGU sensitivity to the mass hierarchy determined using an approximation with an Asimov dataset and an oscillation parameter fit

Resolution of ranking hierarchies in directed networks

Science.gov (United States)

Barucca, Paolo; Lillo, Fabrizio

2018-01-01

Identifying hierarchies and rankings of nodes in directed graphs is fundamental in many applications such as social network analysis, biology, economics, and finance. A recently proposed method identifies the hierarchy by finding the ordered partition of nodes which minimises a score function, termed agony. This function penalises the links violating the hierarchy in a way depending on the strength of the violation. To investigate the resolution of ranking hierarchies we introduce an ensemble of random graphs, the Ranked Stochastic Block Model. We find that agony may fail to identify hierarchies when the structure is not strong enough and the size of the classes is small with respect to the whole network. We analytically characterise the resolution threshold and we show that an iterated version of agony can partly overcome this resolution limit. PMID:29394278

Evaluating, Comparing, and Interpreting Protein Domain Hierarchies

Science.gov (United States)

2014-01-01

Abstract Arranging protein domain sequences hierarchically into evolutionarily divergent subgroups is important for investigating evolutionary history, for speeding up web-based similarity searches, for identifying sequence determinants of protein function, and for genome annotation. However, whether or not a particular hierarchy is optimal is often unclear, and independently constructed hierarchies for the same domain can often differ significantly. This article describes methods for statistically evaluating specific aspects of a hierarchy, for probing the criteria underlying its construction and for direct comparisons between hierarchies. Information theoretical notions are used to quantify the contributions of specific hierarchical features to the underlying statistical model. Such features include subhierarchies, sequence subgroups, individual sequences, and subgroup-associated signature patterns. Underlying properties are graphically displayed in plots of each specific feature's contributions, in heat maps of pattern residue conservation, in “contrast alignments,” and through cross-mapping of subgroups between hierarchies. Together, these approaches provide a deeper understanding of protein domain functional divergence, reveal uncertainties caused by inconsistent patterns of sequence conservation, and help resolve conflicts between competing hierarchies. PMID:24559108

Learning of Alignment Rules between Concept Hierarchies

Science.gov (United States)

Ichise, Ryutaro; Takeda, Hideaki; Honiden, Shinichi

With the rapid advances of information technology, we are acquiring much information than ever before. As a result, we need tools for organizing this data. Concept hierarchies such as ontologies and information categorizations are powerful and convenient methods for accomplishing this goal, which have gained wide spread acceptance. Although each concept hierarchy is useful, it is difficult to employ multiple concept hierarchies at the same time because it is hard to align their conceptual structures. This paper proposes a rule learning method that inputs information from a source concept hierarchy and finds suitable location for them in a target hierarchy. The key idea is to find the most similar categories in each hierarchy, where similarity is measured by the κ(kappa) statistic that counts instances belonging to both categories. In order to evaluate our method, we conducted experiments using two internet directories: Yahoo! and LYCOS. We map information instances from the source directory into the target directory, and show that our learned rules agree with a human-generated assignment 76% of the time.

The quadratic-form identity for constructing Hamiltonian structures of the NLS-MKdV hierarchy and multi-component Levi hierarchy

International Nuclear Information System (INIS)

Dong Huanhe; Wang Xiangrong

2008-01-01

The trace identity is extended to the quadratic-form identity. The Hamiltonian structures of the NLS-MKdV hierarchy, and integrable coupling of multi-component Levi hierarchy are obtained by the quadratic-form identity. The method can be used to produce the Hamiltonian structures of the other integrable couplings or multi-component hierarchies

Neutrino mass hierarchy and matter effects

OpenAIRE

Smirnov, Alexei Yu.

2013-01-01

Matter effects modify the mixing and the effective masses of neutrinos in a way which depends on the neutrino mass hierarchy. Consequently, for normal and inverted hierarchies the oscillations and flavor conversion results are different. Sensitivity to the mass hierarchy appears whenever the matter effects on the 1-3 mixing and mass splitting become substantial. This happens in supernovae in wide energy range and in the matter of the Earth. The Earth density profile is a multi-layer medium wh...

Non-integrability of the Armbruster-Guckenheimer-Kim quartic Hamiltonian through Morales-Ramis theory

OpenAIRE

Acosta-Humánez, P.; Alvarez-Ramírez, M.; Stuchi, T.

2017-01-01

We show the non-integrability of the three-parameter Armburster-Guckenheimer-Kim quartic Hamiltonian using Morales-Ramis theory, with the exception of the three already known integrable cases. We use Poincar\\'e sections to illustrate the breakdown of regular motion for some parameter values.

Hierarchies of belief and interim rationalizability

Directory of Open Access Journals (Sweden)

Jeffrey C. Ely

2006-03-01

Full Text Available In games with incomplete information, conventional hierarchies of belief are incomplete as descriptions of the players' information for the purposes of determining a player's behavior. We show by example that this is true for a variety of solution concepts. We then investigate what is essential about a player's information to identify behavior. We specialize to two player games and the solution concept of interim rationalizability. We construct the universal type space for rationalizability and characterize the types in terms of their beliefs. Infinite hierarchies of beliefs over conditional beliefs, which we call Delta-hierarchies, are what turn out to matter. We show that any two types in any two type spaces have the same rationalizable sets in all games if and only if they have the same Delta-hierarchies.

The problem of symmetry breaking hierarchy

International Nuclear Information System (INIS)

Natale, A.A.

1983-01-01

The problem of symmetry breaking hierarchy in grand unified theories is discussed, proving the impossibility to get a big hierarchy of interactions, in a natural way within the framework of perturbation theory. (L.C.) [pt

Validation Study of Kim's Sham Needle by Measuring Facial Temperature: An N-of-1 Randomized Double-Blind Placebo-Controlled Clinical Trial

Directory of Open Access Journals (Sweden)

Sanghun Lee

2012-01-01

Full Text Available Introduction. In 2008, Kim's sham needle was developed to improve the quality of double-blinded studies. The aim of this study is to validate Kim's sham needle by measuring facial temperature. Methods. We designed “N-of-1” trials involving 7 smokers. One session was composed of 2 stimulations separated by a 2 h washout period. Six sessions were applied daily for all subjects. Infrared thermal imaging was used to examine the effects of acupuncture (HT8, KI2 on facial temperature following smoking-induced decrease. Results. All subjects demonstrated decreased temperatures after sham needle treatment, but 5 of the 7 subjects showed increased temperatures after real needle treatment. 6 of the 7 subjects showed a significant difference (P<0.05 between treatments with real and sham needles. Thus, the physiological stimulation of Kim's sham needle is different from that of a real needle, suggesting that Kim's sham needle is a potential inactive control intervention.

Is there a hierarchy of survival reflexes?

Science.gov (United States)

Macphail, Kieran

2013-10-01

A hierarchy of survival reflexes for prioritising assessment and treatment in patients with pain of insidious onset is hypothesised. The hierarchy asserts that some systems are more vital than others and that the central nervous system (CNS) prioritises systems based on their significance to survival. The hypothesis suggests that dysfunction in more important systems will cause compensation in less important systems. This paper presents studies examining these effects for each system, arguing that each section of the hierarchy may have effects on other systems within the hierarchy. This concept is untested empirically, highly speculative and substantial research is required to validate the suggested hierarchical prioritisation by the CNS. Nonetheless, the hierarchy does provide a theoretical framework to use to exclude contributing systems in patients with pain of insidious onset. Copyright © 2013 Elsevier Ltd. All rights reserved.

Hierarchy in directed random networks.

Science.gov (United States)

Mones, Enys

2013-02-01

In recent years, the theory and application of complex networks have been quickly developing in a markable way due to the increasing amount of data from real systems and the fruitful application of powerful methods used in statistical physics. Many important characteristics of social or biological systems can be described by the study of their underlying structure of interactions. Hierarchy is one of these features that can be formulated in the language of networks. In this paper we present some (qualitative) analytic results on the hierarchical properties of random network models with zero correlations and also investigate, mainly numerically, the effects of different types of correlations. The behavior of the hierarchy is different in the absence and the presence of giant components. We show that the hierarchical structure can be drastically different if there are one-point correlations in the network. We also show numerical results suggesting that the hierarchy does not change monotonically with the correlations and there is an optimal level of nonzero correlations maximizing the level of hierarchy.

Criteria for optimizing cortical hierarchies with continuous ranges

Directory of Open Access Journals (Sweden)

Antje Krumnack

2010-03-01

Full Text Available In a recent paper (Reid et al.; 2009, NeuroImage we introduced a method to calculate optimal hierarchies in the visual network that utilizes continuous, rather than discrete, hierarchical levels, and permits a range of acceptable values rather than attempting to fit fixed hierarchical distances. There, to obtain a hierarchy, the sum of deviations from the constraints that define the hierarchy was minimized using linear optimization. In the short time since publication of that paper we noticed that many colleagues misinterpreted the meaning of the term optimal hierarchy. In particular, a majority of them were under the impression that there was perhaps only one optimal hierarchy, but a substantial difficulty in finding that one. However, there is not only more than one optimal hierarchy but also more than one option for defining optimality. Continuing the line of this work we look at additional options for optimizing the visual hierarchy: minimizing the number of violated constraints and minimizing the maximal size of a constraint violation using linear optimization and mixed integer programming. The implementation of both optimization criteria is explained in detail. In addition, using constraint sets based on the data from Felleman and Van Essen, optimal hierarchies for the visual network are calculated for both optimization methods.

Silica nanoparticle-based dual imaging colloidal hybrids: cancer cell imaging and biodistribution

Directory of Open Access Journals (Sweden)

Lee H

2015-08-01

Full Text Available Haisung Lee,1 Dongkyung Sung,2 Jinhoon Kim,3 Byung-Tae Kim,3 Tuntun Wang,4 Seong Soo A An,5 Soo-Won Seo,6 Dong Kee Yi4 1Molecular Diagnostics, In Vitro Diagnostics Unit, New Business Division, SK Telecom, 2Department of Life Sciences, Graduate School of Korea University, 3Interdisciplinary Graduate Program of Biomedical Engineering, School of Medicine, Sungkyunkwan University, Samsung Medical Center, 4Department of Chemistry, Myongji University, Seoul, 5Department of Bionanotechnology, Gachon Medical Research Institute, Gachon University, Seongnam, 6Medical Device Development Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu, Republic of Korea Abstract: In this study, fluorescent dye-conjugated magnetic resonance (MR imaging agents were investigated in T mode. Gadolinium-conjugated silica nanoparticles were successfully synthesized for both MR imaging and fluorescence diagnostics. Polyamine and polycarboxyl functional groups were modified chemically on the surface of the silica nanoparticles for efficient conjugation of gadolinium ions. The derived gadolinium-conjugated silica nanoparticles were investigated by zeta potential analysis, transmission electron microscopy, inductively coupled plasma mass spectrometry, and energy dispersive x-ray spectroscopy. MR equipment was used to investigate their use as contrast-enhancing agents in T1 mode under a 9.4 T magnetic field. In addition, we tracked the distribution of the gadolinium-conjugated nanoparticles in both lung cancer cells and organs in mice. Keywords: dual bioimaging, MR imaging, silica colloid, T1 contrast imaging, nanohybrid

Constrained KP models as integrable matrix hierarchies

International Nuclear Information System (INIS)

Aratyn, H.; Ferreira, L.A.; Gomes, J.F.; Zimerman, A.H.

1997-01-01

We formulate the constrained KP hierarchy (denoted by cKP K+1,M ) as an affine [cflx sl](M+K+1) matrix integrable hierarchy generalizing the Drinfeld endash Sokolov hierarchy. Using an algebraic approach, including the graded structure of the generalized Drinfeld endash Sokolov hierarchy, we are able to find several new universal results valid for the cKP hierarchy. In particular, our method yields a closed expression for the second bracket obtained through Dirac reduction of any untwisted affine Kac endash Moody current algebra. An explicit example is given for the case [cflx sl](M+K+1), for which a closed expression for the general recursion operator is also obtained. We show how isospectral flows are characterized and grouped according to the semisimple non-regular element E of sl(M+K+1) and the content of the center of the kernel of E. copyright 1997 American Institute of Physics

The Ups and Downs of Hierarchy: the causes and consequences of hierarchy struggles and positional loss

NARCIS (Netherlands)

M.E. Schouten (Maartje)

2016-01-01

markdownabstractScholars have assumed that social hierarchies, the rank ordering of individuals with respect to a valued social dimension within a team, are stable over time. However, hierarchies change and the more changeable they are, the more likely they are to lead to conflicts and have other

A lattice hierarchy and its continuous limits

International Nuclear Information System (INIS)

Fan Engui

2008-01-01

By introducing a discrete spectral problem, we derive a lattice hierarchy which is integrable in Liouville's sense and possesses a multi-Hamiltonian structure. It is show that the discrete spectral problem converges to the well-known AKNS spectral problem under a certain continuous limit. In particular, we construct a sequence of equations in the lattice hierarchy which approximates the AKNS hierarchy as a continuous limit

Neural basis of social status hierarchy across species.

Science.gov (United States)

Chiao, Joan Y

2010-12-01

Social status hierarchy is a ubiquitous principle of social organization across the animal kingdom. Recent findings in social neuroscience reveal distinct neural networks associated with the recognition and experience of social hierarchy in humans, as well as modulation of these networks by personality and culture. Additionally, allelic variation in the serotonin transporter gene is associated with prevalence of social hierarchy across species and cultures, suggesting the importance of the study of genetic factors underlying social hierarchy. Future studies are needed to determine how genetic and environmental factors shape neural systems involved in the production and maintenance of social hierarchy across ontogeny and phylogeny. Copyright © 2010 Elsevier Ltd. All rights reserved.

SDE and SPME Analysis of Flavor Compounds in Jin Xuan Oolong Tea.

Science.gov (United States)

Sheibani, Ershad; Duncan, Susan E; Kuhn, David D; Dietrich, Andrea M; O'Keefe, Sean F

2016-02-01

Simultaneous distillation-extraction (SDE) and solid phase micro extraction (SPME) are procedures used for the isolation of flavor compounds in foods. The purpose of this study was to optimize SDE conditions (solvent and time) and to compare SDE with SPME for the isolation of flavor compounds in Jin Xuan oolong tea using GC-MS and GC-O. The concentration of volatile compounds isolated with diethyl ether was higher (P < 0.05) than for dichloromethane and concentration was higher at 40 min (P < 0.05) than 20 or 60 min extractions. For SDE, 128 volatiles were identified using GC-MS and 45 aroma active compounds using GC-O. Trans-nerolidol was the most abundant compound in oolong tea. The number of volatiles identified using GC-MS was lower in SPME than SDE. For SPME, 59 volatiles and 41 aroma active compounds were identified. The composition of the volatiles isolated by the 2 methods differed considerably but provided complementary information. © 2016 Institute of Food Technologists®

Participatory hierarchies

DEFF Research Database (Denmark)

Kristiansen, Marianne; Bloch-Poulsen, Jørgen

2016-01-01

projects works in the interface between communication and organisation. Third, the methodological purpose is to show that handling of these participatory hierarchies ought to become a goal in OAR projects to be included along with producing practical and theoretical results. The article argues...

An extended integrable fractional-order KP soliton hierarchy

International Nuclear Information System (INIS)

Li Li

2011-01-01

In this Letter, we consider the modified derivatives and integrals of fractional-order pseudo-differential operators. A sequence of Lax KP equations hierarchy and extended fractional KP (fKP) hierarchy are introduced, and the fKP hierarchy has Lax presentations with the extended Lax operators. In the case of the extension with the half-order pseudo-differential operators, a new integrable fKP hierarchy is obtained. A few particular examples of fractional order will be listed, together with their Lax pairs.

Method and System for Making OLAP Hierarchies Summarisable

DEFF Research Database (Denmark)

2002-01-01

Field of Invention: The present invention relates to computer databases, in particular to a method and system for transforming general OLAP hierarchies into summarizable hierarchies. This enables fast query response times for aggregation queries without excessive storage use even when the hierarc......Field of Invention: The present invention relates to computer databases, in particular to a method and system for transforming general OLAP hierarchies into summarizable hierarchies. This enables fast query response times for aggregation queries without excessive storage use even when...

An extended integrable fractional-order KP soliton hierarchy

Energy Technology Data Exchange (ETDEWEB)

Li Li, E-mail: li07099@163.co [College of Maths and Systematic Science, Shenyang Normal University, Shenyang 110034 (China)

2011-01-17

In this Letter, we consider the modified derivatives and integrals of fractional-order pseudo-differential operators. A sequence of Lax KP equations hierarchy and extended fractional KP (fKP) hierarchy are introduced, and the fKP hierarchy has Lax presentations with the extended Lax operators. In the case of the extension with the half-order pseudo-differential operators, a new integrable fKP hierarchy is obtained. A few particular examples of fractional order will be listed, together with their Lax pairs.

Comments on gauge hierarchies

International Nuclear Information System (INIS)

Natale, A.A.

The problem of gauge hierarchy in a O(N) model is discussed. It is shown the existence of an upper bound for the hierarchy of order α- 1 / 2 , as proposed by Gildener. This same constraint appears when the breaking is made by the radiative corrections in a scheme elaborated by Weinberg. It is found that fine tunning or redefinition of coupling constants to improve hieracrchy, as proposed in several papers, cannot be done before the calculation of higher order contributions to the effective potential. (Author) [pt

Probing Neutrino Mass Hierarchy with Supernova

International Nuclear Information System (INIS)

Chakraborty, Sovan

2013-01-01

The rise time of electron antineutrino lightcurve from a Galactic supernova (SN), observable at the IceCube Cherenkov detector, can provide signature of the neutrino mass hierarchy at “large” 1-3 leptonic mixing angle ϑ 13 . In the early accretion phase of the SN, the neutrino oscillations are nontrivial. Due to the matter suppression of collective effects at these early post bounce times, only the MSW resonances in the outer layers of the SN influence the neutrino flux. When the oscillations are taken into account, the signal in IceCube shows sufficiently fast rise time for the inverted mass hierarchy compared to the normal hierarchy. An investigation with an extensive set of stellar core-collapse simulations, provides both qualitative and quantitative robustness of these features. Thus opening another avenue to explore the neutrino mass hierarchy with the rise time of a supernova burst

Two-reduction of the super-KP hierarchy

International Nuclear Information System (INIS)

McArthur, I.N.

1994-01-01

Recursion relations are established for the residues of fractional powers of a two-reduced super-KP operator making use of the Baker-Akhiezer function. These show the integrability of the two-reduced even (or bosonic) flows of the super-KP hierarchy. Similar recursion relations are also proven for the residues of operators associated with the odd (or fermionic) flows of the Mulase-Rabin super-KP hierarchy. Due to the presence of a spectral parameter and itts fermionic partner in the Baker-Akhiezer function, these recursion relations should be relevant to any attempt to prove or disprove a recent proposal that the integrable hierarchy underlying two-dimensional quantum supergravity is the Mulase-Rabin super-KP hierarchy. (orig.)

Hierarchy from baryogenesis

International Nuclear Information System (INIS)

Senatore, Leonardo

2006-01-01

We study a recently proposed mechanism to solve the hierarchy problem in the context of the landscape, where the solution of the hierarchy problem is connected to the requirement of having baryons in our Universe via electroweak baryogenesis. The phase transition is triggered by the fermion condensation of a new gauge sector which becomes strong at a scale Λ determined by dimensional transmutation, and it is mediated to the standard model by a new singlet field. In a 'friendly' neighborhood of the landscape, where only the relevant operators are ''scanned'' among the vacua, baryogenesis is effective only if the Higgs mass m h is comparable to this low scale Λ, forcing m h ∼Λ, and solving the hierarchy problem. A new CP violating phase is needed coupling the new singlet and the Higgs field to new matter fields. We study the constraints on this model given by baryogenesis and by the electron electric dipole moment (EDM), and we briefly comment on gauge coupling unification and on dark matter relic abundance. We find that next generation experiments on the EDM will be sensitive to essentially the entire viable region of the parameter space, so that absence of a signal would effectively rule out the model

Clinical significance of NGAL and KIM-1 for acute kidney injury in patients with scrub typhus.

Directory of Open Access Journals (Sweden)

In O Sun

Full Text Available The aim of this study is to investigate the clinical significance of neutrophil gelatinase-associated lipocalin (NGAL and kidney injury molecule-1 (KIM-1 for acute kidney injury (AKI in patients with scrub typhus.From 2014 to 2015, 145 patients were diagnosed with scrub typhus. Of these, we enrolled 138 patients who were followed up until renal recovery or for at least 3 months. We measured serum and urine NGAL and KIM-1 levels and evaluated prognostic factors affecting scrub typhus-associated AKI.Of the 138 patients, 25 had scrub typhus-associated AKI. The incidence of AKI was 18.1%; of which 11.6%, 4.3%, and 2.2% were classified as risk, injury, and failure, respectively, according to RIFLE criteria. Compared with patients in the non-AKI group, patients in the AKI group were older and showed higher total leukocyte counts and hypoalbuminemia or one or more comorbidities such as hypertension (72% vs 33%, p<0.01, diabetes (40% vs 14%, p<0.01, or chronic kidney disease (32% vs 1%, p<0.01. In addition, serum NGAL values (404± 269 vs 116± 78 ng/mL, P<0.001, KIM-1 values (0.80± 0.52 vs 0.33± 0.68 ng/mL, P<0.001, urine NGAL/creatinine values (371± 672 vs 27± 39 ng/mg, P<0.001 and urine KIM-1/creatinine values (4.04± 2.43 vs 2.38± 1.89 ng/mg, P<0.001 were higher in the AKI group than in the non-AKI group. By multivariate logistic regression, serum NGAL and the presence of chronic kidney disease were significant predictors of AKI.Serum NGAL might be an additive predictor for scrub typhus-associated AKI.

Exposure–response model for sibutramine and placebo: suggestion for application to long-term weight-control drug development

Directory of Open Access Journals (Sweden)

Han S

2015-09-01

Full Text Available Seunghoon Han,1,2 Sangil Jeon,1,2 Taegon Hong,1,2 Jongtae Lee,1,2 Soo Hyeon Bae,1,2 Wan-su Park,1,2 Gab-jin Park,1,2 Sunil Youn,1,2 Doo Yeon Jang,1,2 Kyung-Soo Kim,3 Dong-Seok Yim1,2 1Department of Pharmacology, College of Medicine, The Catholic University of Korea, 2Pharmacometrics Institute for Practical Education and Training, 3Department of Family Medicine, Seoul St Mary’s Hospital, Seochogu, Seoul, Republic of KoreaAbstract: No wholly successful weight-control drugs have been developed to date, despite the tremendous demand. We present an exposure–response model of sibutramine mesylate that can be applied during clinical development of other weight-control drugs. Additionally, we provide a model-based evaluation of sibutramine efficacy. Data from a double-blind, randomized, placebo-controlled, multicenter study were used (N=120. Subjects in the treatment arm were initially given 8.37 mg sibutramine base daily, and those who lost <2 kg after 4 weeks’ treatment were escalated to 12.55 mg. The duration of treatment was 24 weeks. Drug concentration and body weight were measured predose and at 4 weeks, 8 weeks, and 24 weeks after treatment initiation. Exposure and response to sibutramine, including the placebo effect, were modeled using NONMEM 7.2. An asymptotic model approaching the final body weight was chosen to describe the time course of weight loss. Extent of weight loss was described successfully using a sigmoidal exposure–response relationship of the drug with a constant placebo effect in each individual. The placebo effect was influenced by subjects’ sex and baseline body mass index. Maximal weight loss was predicted to occur around 1 year after treatment initiation. The difference in mean weight loss between the sibutramine (daily 12.55 mg and placebo groups was predicted to be 4.5% in a simulation of 1 year of treatment, with considerable overlap of prediction intervals. Our exposure–response model, which

The extended bigraded Toda hierarchy

International Nuclear Information System (INIS)

Carlet, Guido

2006-01-01

We generalize the Toda lattice hierarchy by considering N + M dependent variables. We construct roots and logarithms of the Lax operator which are uniquely defined operators with coefficients that are ε-series of differential polynomials in the dependent variables, and we use them to provide a Lax pair definition of the extended bigraded Toda hierarchy, generalizing [4]. Using R-matrix theory we give the bi-Hamiltonian formulation of this hierarchy and we prove the existence of a tau function for its solutions. Finally we study the dispersionless limit and its connection with a class of Frobenius manifolds on the orbit space of the extended affine Weyl groups W-tilde (N) (A N+M-1 ) of the A series, defined by Dubrovin and Zhang (1998 Compos. Math. 111 167)

Poisson hierarchy of discrete strings

International Nuclear Information System (INIS)

Ioannidou, Theodora; Niemi, Antti J.

2016-01-01

The Poisson geometry of a discrete string in three dimensional Euclidean space is investigated. For this the Frenet frames are converted into a spinorial representation, the discrete spinor Frenet equation is interpreted in terms of a transfer matrix formalism, and Poisson brackets are introduced in terms of the spinor components. The construction is then generalised, in a self-similar manner, into an infinite hierarchy of Poisson algebras. As an example, the classical Virasoro (Witt) algebra that determines reparametrisation diffeomorphism along a continuous string, is identified as a particular sub-algebra, in the hierarchy of the discrete string Poisson algebra. - Highlights: • Witt (classical Virasoro) algebra is derived in the case of discrete string. • Infinite dimensional hierarchy of Poisson bracket algebras is constructed for discrete strings. • Spinor representation of discrete Frenet equations is developed.

Poisson hierarchy of discrete strings

Energy Technology Data Exchange (ETDEWEB)

Ioannidou, Theodora, E-mail: ti3@auth.gr [Faculty of Civil Engineering, School of Engineering, Aristotle University of Thessaloniki, 54249, Thessaloniki (Greece); Niemi, Antti J., E-mail: Antti.Niemi@physics.uu.se [Department of Physics and Astronomy, Uppsala University, P.O. Box 803, S-75108, Uppsala (Sweden); Laboratoire de Mathematiques et Physique Theorique CNRS UMR 6083, Fédération Denis Poisson, Université de Tours, Parc de Grandmont, F37200, Tours (France); Department of Physics, Beijing Institute of Technology, Haidian District, Beijing 100081 (China)

2016-01-28

The Poisson geometry of a discrete string in three dimensional Euclidean space is investigated. For this the Frenet frames are converted into a spinorial representation, the discrete spinor Frenet equation is interpreted in terms of a transfer matrix formalism, and Poisson brackets are introduced in terms of the spinor components. The construction is then generalised, in a self-similar manner, into an infinite hierarchy of Poisson algebras. As an example, the classical Virasoro (Witt) algebra that determines reparametrisation diffeomorphism along a continuous string, is identified as a particular sub-algebra, in the hierarchy of the discrete string Poisson algebra. - Highlights: • Witt (classical Virasoro) algebra is derived in the case of discrete string. • Infinite dimensional hierarchy of Poisson bracket algebras is constructed for discrete strings. • Spinor representation of discrete Frenet equations is developed.

On Recursion Operator of the q -KP Hierarchy

International Nuclear Information System (INIS)

Tian Ke-Lei; Zhu Xiao-Ming; He Jing-Song

2016-01-01

It is the aim of the present article to give a general expression of flow equations of the q-KP hierarchy. The distinct difference between the q-KP hierarchy and the KP hierarchy is due to q-binomial and the action of q-shift operator θ, which originates from the Leibnitz rule of the quantum calculus. We further show that the n-reduction leads to a recursive scheme for these flow equations. The recursion operator for the flow equations of the q-KP hierarchy under the n-reduction is also derived. (paper)

Social influence of a religious hero: the late Cardinal Stephen Kim Sou-hwan's effect on cornea donation and volunteerism.

Science.gov (United States)

Bae, Hyuhn-Suhck; Brown, William J; Kang, Seok

2011-01-01

This study examined the mediated influence of a celebrated religious hero in South Korea, Cardinal Stephen Kim, through two forms of involvement--parasocial interaction and identification--on intention toward cornea donation and volunteerism, and it investigated how the news media diffused of his death. A structural equation modeling analysis with a Web-based voluntary survey of more than 1,200 people in South Korea revealed a multistep social influence process, beginning with parasocial interaction with Cardinal Kim, leading to identification with him, which predicted intention toward cornea donation and volunteerism. Additional investigations found that news of Cardinal Kim's death diffused rapidly through media and interpersonal communication. Results of this study demonstrate that religious leaders who achieve a celebrity hero status can prompt public discussion of important issues rather quickly through extensive media coverage, enabling them to promote prosocial behavior and positively affect public health.

Gauge theories, duality relations and the tensor hierarchy

International Nuclear Information System (INIS)

Bergshoeff, Eric A.; Hohm, Olaf; Hartong, Jelle; Huebscher, Mechthild; OrtIn, Tomas

2009-01-01

We compute the complete 3- and 4-dimensional tensor hierarchies, i.e. sets of p-form fields, with 1 ≤ p ≤ D, which realize an off-shell algebra of bosonic gauge transformations. We show how these tensor hierarchies can be put on-shell by introducing a set of duality relations, thereby introducing additional scalars and a metric tensor. These so-called duality hierarchies encode the equations of motion of the bosonic part of the most general gauged supergravity theories in those dimensions, including the (projected) scalar equations of motion. We construct gauge-invariant actions that include all the fields in the tensor hierarchies. We elucidate the relation between the gauge transformations of the p-form fields in the action and those of the same fields in the tensor hierarchy.

Quantify entanglement by concurrence hierarchy

OpenAIRE

Fan, Heng; Matsumoto, Keiji; Imai, Hiroshi

2002-01-01

We define the concurrence hierarchy as d-1 independent invariants under local unitary transformations in d-level quantum system. The first one is the original concurrence defined by Wootters et al in 2-level quantum system and generalized to d-level pure quantum states case. We propose to use this concurrence hierarchy as measurement of entanglement. This measurement does not increase under local quantum operations and classical communication.

Two New Reformulation Convexification Based Hierarchies for 0-1 MIPs

Directory of Open Access Journals (Sweden)

Hacene Ouzia

2015-01-01

Full Text Available First, we introduce two new reformulation convexification based hierarchies called RTC and RSC for which the rank d continuous relaxations are denoted by P^RTCd and P^RSCd, respectively. These two hierarchies are obtained using two different convexification schemes: term convexification in the case of the RTC hierarchy and standard convexification in the case of the RSC hierarchy. Secondly, we compare the strength of these two hierarchies. We will prove that (i the hierarchy RTC is equivalent to the RLT hierarchy of Sherali-Adams, (ii the hierarchy RTC dominates the hierarchy RSC, and (iii the hierarchy RSC is dominated by the Lift-and-Project hierarchy. Thirdly, for every rank d, we will prove that convTd∩Etd⊆P^RTCd⊆Td and convSd∩Esd⊆P^RSCd⊆Sd where the sets Td and Sd are convex, while Etd and Esd are two nonconvex sets with empty interior (all these sets depend on the convexification step. The first inclusions allow, in some cases, an explicit characterization (in the space of the original variables of the RLT relaxations. Finally, we will discuss weak version of both RTC and RSC hierarchies and we will emphasize some connections between them.

Global Policing and the Case of Kim Dotcom

Directory of Open Access Journals (Sweden)

Darren Palmer

2013-11-01

Full Text Available In early 2012, 76 heavily armed police conducted a raid on a house in Auckland, New Zealand. The targets were Kim Dotcom, a German national with a NZ residency visa, and several colleagues affiliated with Megaupload, an online subscription-based peer-to-peer (P2P file sharing facility. The alleged offences involved facilitating unlawful file sharing and United States federal criminal copyright violations. Following the raid, several court cases provide valuable insights into emerging ‘global policing’ practices (Bowling and Sheptycki 2012 based on communications between sovereign enforcement agencies.  This article uses these cases to explore the growth of ‘extraterritorial’ police powers that operate ‘across borders’ (Nadelmann 1993 as part of several broader transformations of global policing in the digital age.

Special polynomials associated with rational solutions of some hierarchies

International Nuclear Information System (INIS)

Kudryashov, Nikolai A.

2009-01-01

New special polynomials associated with rational solutions of the Painleve hierarchies are introduced. The Hirota relations for these special polynomials are found. Differential-difference hierarchies to find special polynomials are presented. These formulae allow us to search special polynomials associated with the hierarchies. It is shown that rational solutions of the Caudrey-Dodd-Gibbon, the Kaup-Kupershmidt and the modified hierarchy for these ones can be obtained using new special polynomials.

CXCL14 Blockade of CXCL12/CXCR4 Signaling in Prostate Cancer Bone Metastasis

Science.gov (United States)

2017-10-01

10.1158/0008-5472.CAN-04-3785. 55. Jung Y, Kim JK, Shiozawa Y, Wang J, Mishra A, Joseph J, Berry JE, McGee S, Lee E, Sun H, Wang J, Jin T, Zhang H...and unfortunate complication of advanced prostate cancer resulting in significant pain and fractures . The most devastating consequence, however, is...treatments. These data suggest a mechanism of increased migration and invasion may be associated with expression of EMT genes. Regulation of Kinase

Status hierarchy, attractiveness hierarchy and sex ratio : Three contextual factors explaining the status-aggression link among adolescents

NARCIS (Netherlands)

Zwaan, Michiel; Dijkstra, Jan; Veenstra, René

The moderating effects of three specific conditions (status hierarchy, attractiveness hierarchy and sex ratio) on the link between status (popularity) and physical and relational aggression were examined in a large sample of adolescent boys (N = 1,665) and girls (N = 1,637) (M age = 13.60). In line

When Do Types Induce the Same Belief Hierarchy?

Directory of Open Access Journals (Sweden)

Andrés Perea

2016-10-01

Full Text Available Type structures are a simple device to describe higher-order beliefs. However, how can we check whether two types generate the same belief hierarchy? This paper generalizes the concept of a type morphism and shows that one type structure is contained in another if and only if the former can be mapped into the other using a generalized type morphism. Hence, every generalized type morphism is a hierarchy morphism and vice versa. Importantly, generalized type morphisms do not make reference to belief hierarchies. We use our results to characterize the conditions under which types generate the same belief hierarchy.

A health hierarchy of effects model: a synthesis of advertising and health hierarchy conceptualizations.

Science.gov (United States)

Rouse, R A

1991-01-01

Work by both advertising and health researchers has independently yielded hierarchy of effects models which can be used to predict campaign success. Unfortunately, however, previous work has been criticized as "common sense" approaches which are more "assumed" than "proven." This analysis argues that much of the problem is due to the lack of precision often associated with over-simplified "uni-dimensional" models. Instead, this perspective synthesized a "two-dimensional" health hierarchy of effects model and outlines a pragmatic strategy for campaign measurement.

Improving Expression Power in Modeling OLAP Hierarchies

Science.gov (United States)

Malinowski, Elzbieta

Data warehouses and OLAP systems form an integral part of modern decision support systems. In order to exploit both systems to their full capabilities hierarchies must be clearly defined. Hierarchies are important in analytical applications, since they provide users with the possibility to represent data at different abstraction levels. However, even though there are different kinds of hierarchies in real-world applications and some are already implemented in commercial tools, there is still a lack of a well-accepted conceptual model that allows decision-making users express their analysis needs. In this paper, we show how the conceptual multidimensional model can be used to facilitate the representation of complex hierarchies in comparison to their representation in the relational model and commercial OLAP tool, using as an example Microsoft Analysis Services.

Sato theory on the q-Toda hierarchy and its extension

International Nuclear Information System (INIS)

Li, Chuanzhong

2015-01-01

In this paper, we construct the Sato theory including the Hirota bilinear equations and tau function of a new q-deformed Toda hierarchy (QTH). Meanwhile the Block type additional symmetry and bi-Hamiltonian structure of this hierarchy are given. From Hamiltonian tau symmetry, we give another definition of tau function of this hierarchy. Afterwards, we extend the q-Toda hierarchy to an extended q-Toda hierarchy (EQTH) which satisfy a generalized Hirota quadratic equation in terms of generalized vertex operators. The Hirota quadratic equation might have further application in Gromov–Witten theory. The corresponding Sato theory including multi-fold Darboux transformations of this extended hierarchy is also constructed. At last, we construct the multicomponent extension of the q-Toda hierarchy and show the integrability including its bi-Hamiltonian structure, tau symmetry and conserved densities

Symmetries of supersymmetric integrable hierarchies of KP type

International Nuclear Information System (INIS)

Nissimov, E.; Pacheva, S.

2002-01-01

This article is devoted to the systematic study of additional (non-isospectral) symmetries of constrained (reduced) supersymmetric integrable hierarchies of KP type--the so-called SKP (R;M B ,M F ) models. The latter are supersymmetric extensions of ordinary constrained KP hierarchies which contain as special cases basic integrable systems such as (m)KdV, AKNS, Fordy-Kulish, Yajima-Oikawa, etc. As a first main result it is shown that any SKP (R;M B ,M F ) hierarchy possesses two different mutually (anti-)commuting types of superloop superalgebra additional symmetries corresponding to the positive- and negative-grade parts of certain superloop superalgebras. The second main result is the systematic construction of the full algebra of additional Virasoro symmetries of SKP (R;M B ,M F ) hierarchies, which requires nontrivial modifications of the Virasoro flows known from the general case of unconstrained Manin-Radul super-KP hierarchies (the latter flows do not define symmetries for constrained SKP (R;M B ,M F ) hierarchies). As a third main result we provide systematic construction of the supersymmetric analogs of multi-component (matrix) KP hierarchies and show that the latter contain, among others, the supersymmetric version of the Davey-Stewartson system. Finally, we present an explicit derivation of the general Darboux-Baecklund solutions for the SKP (R;M B ,M F ) super-tau functions (supersymmetric 'soliton'-like solutions) which preserve the additional (non-isospectral) symmetries

Status Hierarchy, Attractiveness Hierarchy and Sex Ratio: Three Contextual Factors Explaining the Status-Aggression Link among Adolescents

Science.gov (United States)

Zwaan, Michiel; Dijkstra, Jan Kornelis; Veenstra, Rene

2013-01-01

The moderating effects of three specific conditions (status hierarchy, attractiveness hierarchy and sex ratio) on the link between status (popularity) and physical and relational aggression were examined in a large sample of adolescent boys ("N" = 1,665) and girls ("N" = 1,637) ("M" age = 13.60). In line with the…

North Korea after Kim Chong-il: Leadership Dynamics and Potential Crisis Scenarios

Science.gov (United States)

2011-11-01

legal responsibility, and with specified procedures , the actual process is different.3 To date, regime dynamics in the Kim Chong-il era have been... procedures and regulations provide the outlines of formal rule, the 3 For a detailed examination of how...was also made an alternate member. It is also worth noting that 10 of the 12 members of the NDC were represented in the new Politburo lineup , thus

Inequality matters: classroom status hierarchy and adolescents' bullying.

Science.gov (United States)

Garandeau, Claire F; Lee, Ihno A; Salmivalli, Christina

2014-07-01

The natural emergence of status hierarchies in adolescent peer groups has long been assumed to help prevent future intragroup aggression. However, clear evidence of this beneficial influence is lacking. In fact, few studies have examined between-group differences in the degree of status hierarchy (defined as within-group variation in individual status) and how they are related to bullying, a widespread form of aggression in schools. Data from 11,296 eighth- and ninth-graders (mean age = 14.57, 50.6 % female) from 583 classes in 71 schools were used to determine the direction of the association between classroom degree of status hierarchy and bullying behaviors, and to investigate prospective relationships between these two variables over a 6-month period. Multilevel structural equation modeling analyses showed that higher levels of classroom status hierarchy were concurrently associated with higher levels of bullying at the end of the school year. Higher hierarchy in the middle of the school year predicted higher bullying later in the year. No evidence was found to indicate that initial bullying predicted future hierarchy. These findings highlight the importance of a shared balance of power in the classroom for the prevention of bullying among adolescents.

Modelling Dominance Hierarchies Under Winner and Loser Effects.

Science.gov (United States)

Kura, Klodeta; Broom, Mark; Kandler, Anne

2015-06-01

Animals that live in groups commonly form themselves into dominance hierarchies which are used to allocate important resources such as access to mating opportunities and food. In this paper, we develop a model of dominance hierarchy formation based upon the concept of winner and loser effects using a simulation-based model and consider the linearity of our hierarchy using existing and new statistical measures. Two models are analysed: when each individual in a group does not know the real ability of their opponents to win a fight and when they can estimate their opponents' ability every time they fight. This estimation may be accurate or fall within an error bound. For both models, we investigate if we can achieve hierarchy linearity, and if so, when it is established. We are particularly interested in the question of how many fights are necessary to establish a dominance hierarchy.

Principles of synchronous digital hierarchy

CERN Document Server

Jain, Rajesh Kumar

2012-01-01

The book presents the current standards of digital multiplexing, called synchronous digital hierarchy, including analog multiplexing technologies. It is aimed at telecommunication professionals who want to develop an understanding of digital multiplexing and synchronous digital hierarchy in particular and the functioning of practical telecommunication systems in general. The text includes all relevant fundamentals and provides a handy reference for problem solving or defining operations and maintenance strategies. The author covers digital conversion and TDM principles, line coding and digital

Solution of the gauge hierarchy problem

International Nuclear Information System (INIS)

Dimopoulos, S.; Georgi, H.

1982-01-01

We propose a novel solution to the gauge hierarchy problem in theories with softly broken supersymmetry. Quantum effects can resuscitate classically sick theories, producing the large scale from the small supersymmetry breaking scale. We use this mechanism to construct realistic SU(6) and SU(5) GUTs which do not suffer from gauge hierarchy or fine tuning problems. (orig.)

A quark interpretation of the combinatorial hierarchy

International Nuclear Information System (INIS)

Enqvist, Kari.

1979-01-01

We propose a physical interpretation of the second level of the combinatorial hierarchy in terms of three quarks, three antiquarks and the vacuum. This interpretation allows us to introduce a new quantum number, which measures electromagnetic mass splitting of the quarks. We extend our argument by analogue to baryons, and find some SU(3) and some new mass formulas for baryons. The generalization of our approach to other hierarchy levels is discussed. We present also an empirical mass formula for baryons, which seems to be loosely connected with the combinatorial hierarchy. (author)

W-algebra symmetries of generalised Drinfel'd-Sokolov hierarchies

International Nuclear Information System (INIS)

Spence, B.

1992-01-01

Using the zero curvature formulation, it is shown that W-algebra transformations are symmetries of corresponding generalised Drinfel'd-Sokolov hierarchies. This result is illustrated with the examples of the KdV and Boussinesque hierarchies, and the hierarchy associated to the Polyakov-Bershadsky W-algebra. (orig.)

Visual Hierarchy and Mind Motion in Advertising Design

Directory of Open Access Journals (Sweden)

Doaa Farouk Badawy Eldesouky

2013-06-01

Full Text Available Visual hierarchy is a significant concept in the field of advertising, a field that is dominated by effective communication, visual recognition and motion. Designers of advertisements have always been trying to organize the visual hierarchy throughout their advertising designs to aid the eye to recognize information in the desired order, to achieve the ultimate goals of clear perception and effectively delivering the advertising messages. However many assumptions and questions usually rise on how to create effective hierarchy throughout advertising designs and lead the eye and mind of the viewer in the most favorable way. This paper attempts to study visual hierarchy and mind motion in advertising designs and why it is important to develop visual paths when designing an advertisement. It explores the theory behind it, and how the very principles can be used to put these concepts into practice. The paper demonstrates some advertising samples applying visual hierarchy and mind motion in a representation of applying the basics and discussing the results.

Visual Hierarchy and Mind Motion in Advertising Design

Directory of Open Access Journals (Sweden)

Doaa Farouk Badawy Eldesouky

2013-06-01

Full Text Available Visual hierarchy is a significant concept in the field of advertising, a field that is dominated by effective communication, visual recognition and motion. Designers of advertisements have always been trying to organize the visual hierarchy throughout their advertising designs to aid the eye to recognize information in the desired order, to achieve the ultimate goals of clear perception and effectively delivering the advertising messages. However many assumptions and questions usually rise on how to create effective hierarchy throughout advertising designs and lead the eye and mind of the viewer in the most favorable way. This paper attempts to study visual hierarchy and mind motion in advertising designs and why it is important to develop visual paths when designing an advertisement. It explores the theory behind it, and how the very principles can be used to put these concepts into practice. The paper demonstrates some advertising samples applying visual hierarchy and mind motion in a representation of applying the basics and discussing the results. 

The Helmholtz Hierarchy: phase space statistics of cold dark matter

International Nuclear Information System (INIS)

Tassev, Svetlin V.

2011-01-01

We present a new formalism to study large-scale structure in the universe. The result is a hierarchy (which we call the ''Helmholtz Hierarchy'') of equations describing the phase space statistics of cold dark matter (CDM). The hierarchy features a physical ordering parameter which interpolates between the Zel'dovich approximation and fully-fledged gravitational interactions. The results incorporate the effects of stream crossing. We show that the Helmholtz hierarchy is self-consistent and obeys causality to all orders. We present an interpretation of the hierarchy in terms of effective particle trajectories

Baecklund transformation of the noncommutative Gelfand-Dickey hierarchy

International Nuclear Information System (INIS)

Zheng Zhong; He Jingsong; Cheng Yi

2004-01-01

We study the Baecklund transformation of the noncommutative Gelfand-Dickey(ncGD) hierarchy. By factorizing its Lax operator into the multiplication form of first order differential operator, the noncommutative modified KdV(ncMKdV) hierarchy and the Miura transformations are defined. Our results show that the ncMKdV equations are invariant under the cyclic permutation, and hence induces the Baecklund transformation of the ncGD hierarchy. (author)

A hierarchy of Liouville integrable discrete Hamiltonian equations

Energy Technology Data Exchange (ETDEWEB)

Xu Xixiang [College of Science, Shandong University of Science and Technology, Qingdao 266510 (China)], E-mail: xixiang_xu@yahoo.com.cn

2008-05-12

Based on a discrete four-by-four matrix spectral problem, a hierarchy of Lax integrable lattice equations with two potentials is derived. Two Hamiltonian forms are constructed for each lattice equation in the resulting hierarchy by means of the discrete variational identity. A strong symmetry operator of the resulting hierarchy is given. Finally, it is shown that the resulting lattice equations are all Liouville integrable discrete Hamiltonian systems.

Recommended HSE-7 documents hierarchy

International Nuclear Information System (INIS)

Klein, R.B.; Jennrich, E.A.; Lund, D.M.; Danna, J.G.; Davis, K.D.; Rutz, A.C.

1990-01-01

This report recommends a hierarchy of waste management documents at Los Alamos National Laboratory (LANL or ''Laboratory''). The hierarchy addresses documents that are required to plan, implement, and document waste management programs at Los Alamos. These documents will enable the waste management group and the six sections contained within that group to satisfy requirements that are imposed upon them by the US Department of Energy (DOE), DOE Albuquerque Operations, US Environmental Protection Agency, various State of New Mexico agencies, and Laboratory management

Enhanced oral bioavailability of valsartan using a polymer-based supersaturable self-microemulsifying drug delivery system

Directory of Open Access Journals (Sweden)

Yeom DW

2017-05-01

Full Text Available Dong Woo Yeom,1,* Bo Ram Chae,2,* Ho Yong Son,1 Jin Han Kim,1 Jun Soo Chae,1 Seh Hyon Song,2 Dongho Oh,2 Young Wook Choi1 1College of Pharmacy, Chung-Ang University, Seoul, 2Daewon Pharm. Co., Ltd, Seoul, Republic of Korea *These authors contributed equally to this work Abstract: A novel, supersaturable self-microemulsifying drug delivery system (S-SMEDDS was successfully formulated to enhance the dissolution and oral absorption of valsartan (VST, a poorly water-soluble drug, while reducing the total quantity for administration. Poloxamer 407 is a selectable, supersaturating agent for VST-containing SMEDDS composed of 10% Capmul® MCM, 45% Tween® 20, and 45% Transcutol® P. The amounts of SMEDDS and Poloxamer 407 were chosen as formulation variables for a 3-level factorial design. Further optimization was established by weighting different levels of importance on response variables for dissolution and total quantity, resulting in an optimal S-SMEDDS in large quantity (S-SMEDDS_LQ; 352 mg in total and S-SMEDDS in reduced quantity (S-SMEDDS_RQ; 144.6 mg in total. Good agreement was observed between predicted and experimental values for response variables. Consequently, compared with VST powder or suspension and SMEDDS, both S-SMEDDS_LQ and S-SMEDDS_RQ showed excellent in vitro dissolution and in vivo oral bioavailability in rats. The magnitude of dissolution and absorption-enhancing capacities using quantity-based comparisons was in the order S-SMEDDS_RQ > S-SMEDDS_LQ > SMEDDS > VST powder or suspension. Thus, we concluded that, in terms of developing an effective SMEDDS preparation with minimal total quantity, S-SMEDDS_RQ is a promising candidate. Keywords: valsartan, SMEDDS, supersaturation, factorial design, optimization, bio­availability 

A model of Yukawa hierarchies

International Nuclear Information System (INIS)

Elwood, J.K.; Irges, N.; Ramond, P.

1997-05-01

The authors present a model for the observed hierarchies among the Yukawa couplings of the standard model in the context of an effective low energy theory with an anomalous U(1) symmetry. This symmetry, a generic feature of superstring compactification, is a remnant of the Green-Schwarz anomaly cancellation mechanism. The gauge group is that of the standard model, augmented by X, the anomalous U(1), and two family-dependent phase symmetries Y (1) and Y (2) . The correct hierarchies are reproduced only when sin 2 θ w = 3/8 at the cut-off. To cancel anomalies, right-handed neutrinos and other standard model singlets must be introduced. Independently of the charges of the right-handed neutrinos, this model produces the same neutrino mixing matrix and an inverted hierarchy of neutrino masses. The heaviest is the electron neutrino with a mass ∼ 1 meV, and mixing of the order of λ c 3 with each of the other two neutrinos

Conformal fields. From Riemann surfaces to integrable hierarchies

International Nuclear Information System (INIS)

Semikhatov, A.M.

1991-01-01

I discuss the idea of translating ingredients of conformal field theory into the language of hierarchies of integrable differential equations. Primary conformal fields are mapped into (differential or matrix) operators living on the phase space of the hierarchy, whereas operator insertions of, e.g., a current or the energy-momentum tensor, become certain vector fields on the phase space and thus acquire a meaning independent of a given Riemann surface. A number of similarities are observed between the structures arising on the hierarchy and those of the theory on the world-sheet. In particular, there is an analogue of the operator product algebra with the Cauchy kernel replaced by its 'off-shell' hierarchy version. Also, hierarchy analogues of certain operator insertions admit two (equivalent, but distinct) forms, resembling the 'bosonized' and 'fermionized' versions respectively. As an application, I obtain a useful reformulation of the Virasoro constraints of the type that arise in matrix models, as a system of equations on dressing (or Lax) operators (rather than correlation functions, i.e., residues or traces). This also suggests an interpretation in terms of a 2D topological field theory, which might be extended to a correspondence between Virasoro-constrained hierarchies and topological theories. (orig.)

Urinary KIM-1, NGAL and L-FABP for the diagnosis of AKI in patients with acute coronary syndrome or heart failure undergoing coronary angiography.

Science.gov (United States)

Torregrosa, Isidro; Montoliu, Carmina; Urios, Amparo; Andrés-Costa, María Jesús; Giménez-Garzó, Carla; Juan, Isabel; Puchades, María Jesús; Blasco, María Luisa; Carratalá, Arturo; Sanjuán, Rafael; Miguel, Alfonso

2015-11-01

Acute kidney injury (AKI) is a common complication after coronary angiography. Early biomarkers of this disease are needed since increase in serum creatinine levels is a late marker. To assess the usefulness of urinary kidney injury molecule-1 (uKIM-1), neutrophil gelatinase-associated lipocalin (uNGAL) and liver-type fatty acid-binding protein (uL-FABP) for early detection of AKI in these patients, comparing their performance with another group of cardiac surgery patients. Biomarkers were measured in 193 patients, 12 h after intervention. In the ROC analysis, AUC for KIM-1, NGAL and L-FABP was 0.713, 0.958 and 0.642, respectively, in the coronary angiography group, and 0.716, 0.916 and 0.743 in the cardiac surgery group. Urinary KIM-1 12 h after intervention is predictive of AKI in adult patients undergoing coronary angiography, but NGAL shows higher sensitivity and specificity. L-FABP provides inferior discrimination for AKI than KIM-1 or NGAL in contrast to its performance after cardiac surgery. This is the first study showing the predictive capacity of KIM-1 for AKI after coronary angiography. Further studies are still needed to answer relevant questions about the clinical utility of biomarkers for AKI in different clinical settings.

A new multi-component hierarchy and its integrable expanding model

International Nuclear Information System (INIS)

Dong Huanhe; Liang Xiangqian

2008-01-01

A set of multi-component matrix Lie algebra is constructed, it follows that a type of new loop algebra is presented and multi-component integrable hierarchy is obtained. Furthermore, the loop algebra is expanded into a larger one and a type of integrable coupling system is worked out. As reduction of the hierarchy, some well-known hierarchy such as DNLS, KN, CLL hierarchy are established

Dark energy and the hierarchy problem

International Nuclear Information System (INIS)

Chen, Pisin

2007-01-01

The well-known hierarchy between the Planck scale (∼10 19 GeV) and the TeV scale, namely a ratio of ∼10 16 between the two, is coincidentally repeated in a inverted order between the TeV scale and the dark energy scale at ∼10 -3 eV implied by the observations. We argue that this is not a numerical coincidence. The same brane-world setups to address the first hierarchy problem may also in principle address this second hierarchy issue. Specifically, we consider supersymmetry in the bulk and its breaking on the brane and resort to the Casimir energy induced by the bulk graviton-gravitino mass-shift on the brane as the dark energy. For the ADD model we found that our notion is sensible only if the number of extra dimension n=2. We extend our study to the Randall-Sundrum model. Invoking the chirality-flip on the boundaries for SUSY-breaking, the zero-mode gravitino contribution to the Casimir energy does give rise to the double hierarchy. Unfortunately since the higher Kaluza-Klein modes acquire relative mass-shifts at the TeV level, the zero-mode contribution to Casimir energy is overshadowed

1029: Tranexamic Acid for Pediatric Trauma

Science.gov (United States)

2014-12-01

parts. Of total 74 cases of rib fracture , the number of fracture between bone scan and CT are identical in only 9 cases (12%), and different in 65...OF BONE SCANNING IN THE DIAGNOSIS OF HIDDEN FRACTURE IN MAJOR TRAUMA PATIENTS Hang Joo Cho1, Sung Jeep Kim1, Jin Seok Baek2; 1The Catholic University...the hidden fracture . We investi- gated the usefulness of bone scan in the diagnosis of hidden fracture of major trauma patients. Methods: This study

Why and when hierarchy impacts team effectiveness: A meta-analytic integration.

Science.gov (United States)

Greer, Lindred L; de Jong, Bart A; Schouten, Maartje E; Dannals, Jennifer E

2018-06-01

Hierarchy has the potential to both benefit and harm team effectiveness. In this article, we meta-analytically investigate different explanations for why and when hierarchy helps or hurts team effectiveness, drawing on results from 54 prior studies (N = 13,914 teams). Our findings show that, on net, hierarchy negatively impacts team effectiveness (performance: ρ = -.08; viability: ρ = -.11), and that this effect is mediated by increased conflict-enabling states. Additionally, we show that the negative relationship between hierarchy and team performance is exacerbated by aspects of the team structure (i.e., membership instability, skill differentiation) and the hierarchy itself (i.e., mutability), which make hierarchical teams prone to conflict. The predictions regarding the positive effect of hierarchy on team performance as mediated by coordination-enabling processes, and the moderating roles of several aspects of team tasks (i.e., interdependence, complexity) and the hierarchy (i.e., form) were not supported, with the exception that task ambiguity enhanced the positive effects of hierarchy. Given that our findings largely support dysfunctional views on hierarchy, future research is needed to understand when and why hierarchy may be more likely to live up to its purported functional benefits. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

Stress amplifies memory for social hierarchy.

Science.gov (United States)

Cordero, María Isabel; Sandi, Carmen

2007-11-01

Individuals differ in their social status and societies in the extent of social status differences among their members. There is great interest in understanding the key factors that contribute to the establishment of social dominance structures. Given that stress can affect behavior and cognition, we hypothesized that, given equal opportunities to become either dominant or submissive, stress experienced by one of the individuals during their first encounter would determine the long-term establishment of a social hierarchy by acting as a two-stage rocket: (1) by influencing the rank achieved after a social encounter and (2) by facilitating and/or promoting a long-term memory for the specific hierarchy. Using a novel model for the assessment of long-term dominance hierarchies in rats, we present here the first evidence supporting such hypothesis. In control conditions, the social rank established through a first interaction and food competition test between two male rats is not maintained when animals are confronted 1 week later. However, if one of the rats is stressed just before their first encounter, the dominance hierarchy developed on day 1 is still clearly observed 1 week later, with the stressed animal becoming submissive (i.e., looser in competition tests) in both social interactions. Our findings also allow us to propose that stress potentiates a hierarchy-linked recognition memory between "specific" individuals through mechanisms that involve de novo protein synthesis. These results implicate stress among the key mechanisms contributing to create social imbalance and highlight memory mechanisms as key mediators of stress-induced long-term establishment of social rank.

Stress amplifies memory for social hierarchy

Directory of Open Access Journals (Sweden)

María I Cordero

2007-10-01

Full Text Available Individuals differ in their social status and societies in the extent of social status differences among their members. There is great interest in understanding the key factors that contribute to the establishment of social dominance structures. Given that stress can affect behavior and cognition, we hypothesized that, given equal opportunities to become either dominant or submissive, stress experienced by one of the individuals during their first encounter would determine the long-term establishment of a social hierarchy by acting as a two-stage rocket: (1 by influencing the rank achieved after a social encounter and (2 by facilitating and/or promoting a long-term memory for the specific hierarchy. Using a novel model for the assessment of long-term dominance hierarchies in rats, we present here the first evidence supporting such hypothesis. In control conditions, the social rank established through a first interaction and food competition test between two male rats is not maintained when animals are confronted 1 week later. However, if one of the rats is stressed just before their first encounter, the dominance hierarchy developed on day 1 is still clearly observed 1 week later, with the stressed animal becoming submissive (i.e., looser in competition tests in both social interactions. Our findings also allow us to propose that stress potentiates a hierarchy-linked recognition memory between “specific” individuals through mechanisms that involve de novo protein synthesis. These results implicate stress among the key mechanisms contributing to create social imbalance and highlight memory mechanisms as key mediators of stress-induced long-term establishment of social rank.

Diglossie et biculturalisme littéraires :le cas de A Free Life, de Ha Jin

OpenAIRE

Perrin, Isabelle

2013-01-01

Le roman La Liberté de vivre, de Ha Jin, place son lecteur face à un type d’« écriture-traduction », puisqu’il suit le parcours d’un Chinois contraint par son exil aux États-Unis après les événements de Tian’anmen d’adopter la langue et la culture américaines. La représentation mimétique du réel joue sur le concept d’étrangeté, que le texte fait fonctionner en miroir : étrangeté des référents langagiers et culturels américains pour le héros chinois, étrangeté des référents langagiers et cultu...

Operator approach to solutions of the constrained BKP hierarchy

International Nuclear Information System (INIS)

Shen, Hsin-Fu; Lee, Niann-Chern; Tu, Ming-Hsien

2011-01-01

The operator formalism to the vector k-constrained BKP hierarchy is presented. We solve the Hirota bilinear equations of the vector k-constrained BKP hierarchy via the method of neutral free fermion. In particular, by choosing suitable group element of O(∞), we construct rational and soliton solutions of the vector k-constrained BKP hierarchy.

A Suggested Modification to Maslow's Need Hierarchy

Science.gov (United States)

Groves, David L.; And Others

1975-01-01

Since its development, Maslow's need hierarchy has been criticized and applauded. This investigation was undertaken to explore a modification of the upper levels of the need hierarchy based upon the application of power, competition, and achievement to self, as well as the concept of "other directed." (Author)

Optimal mesh hierarchies in Multilevel Monte Carlo methods

KAUST Repository

Von Schwerin, Erik

2016-01-01

I will discuss how to choose optimal mesh hierarchies in Multilevel Monte Carlo (MLMC) simulations when computing the expected value of a quantity of interest depending on the solution of, for example, an Ito stochastic differential equation or a partial differential equation with stochastic data. I will consider numerical schemes based on uniform discretization methods with general approximation orders and computational costs. I will compare optimized geometric and non-geometric hierarchies and discuss how enforcing some domain constraints on parameters of MLMC hierarchies affects the optimality of these hierarchies. I will also discuss the optimal tolerance splitting between the bias and the statistical error contributions and its asymptotic behavior. This talk presents joint work with N.Collier, A.-L.Haji-Ali, F. Nobile, and R. Tempone.

Optimal mesh hierarchies in Multilevel Monte Carlo methods

KAUST Repository

Von Schwerin, Erik

2016-01-08

I will discuss how to choose optimal mesh hierarchies in Multilevel Monte Carlo (MLMC) simulations when computing the expected value of a quantity of interest depending on the solution of, for example, an Ito stochastic differential equation or a partial differential equation with stochastic data. I will consider numerical schemes based on uniform discretization methods with general approximation orders and computational costs. I will compare optimized geometric and non-geometric hierarchies and discuss how enforcing some domain constraints on parameters of MLMC hierarchies affects the optimality of these hierarchies. I will also discuss the optimal tolerance splitting between the bias and the statistical error contributions and its asymptotic behavior. This talk presents joint work with N.Collier, A.-L.Haji-Ali, F. Nobile, and R. Tempone.

The Evolutionary Origins of Hierarchy.

Science.gov (United States)

Mengistu, Henok; Huizinga, Joost; Mouret, Jean-Baptiste; Clune, Jeff

2016-06-01

Hierarchical organization-the recursive composition of sub-modules-is ubiquitous in biological networks, including neural, metabolic, ecological, and genetic regulatory networks, and in human-made systems, such as large organizations and the Internet. To date, most research on hierarchy in networks has been limited to quantifying this property. However, an open, important question in evolutionary biology is why hierarchical organization evolves in the first place. It has recently been shown that modularity evolves because of the presence of a cost for network connections. Here we investigate whether such connection costs also tend to cause a hierarchical organization of such modules. In computational simulations, we find that networks without a connection cost do not evolve to be hierarchical, even when the task has a hierarchical structure. However, with a connection cost, networks evolve to be both modular and hierarchical, and these networks exhibit higher overall performance and evolvability (i.e. faster adaptation to new environments). Additional analyses confirm that hierarchy independently improves adaptability after controlling for modularity. Overall, our results suggest that the same force-the cost of connections-promotes the evolution of both hierarchy and modularity, and that these properties are important drivers of network performance and adaptability. In addition to shedding light on the emergence of hierarchy across the many domains in which it appears, these findings will also accelerate future research into evolving more complex, intelligent computational brains in the fields of artificial intelligence and robotics.

The Evolutionary Origins of Hierarchy

Science.gov (United States)

Huizinga, Joost; Clune, Jeff

2016-01-01

Hierarchical organization—the recursive composition of sub-modules—is ubiquitous in biological networks, including neural, metabolic, ecological, and genetic regulatory networks, and in human-made systems, such as large organizations and the Internet. To date, most research on hierarchy in networks has been limited to quantifying this property. However, an open, important question in evolutionary biology is why hierarchical organization evolves in the first place. It has recently been shown that modularity evolves because of the presence of a cost for network connections. Here we investigate whether such connection costs also tend to cause a hierarchical organization of such modules. In computational simulations, we find that networks without a connection cost do not evolve to be hierarchical, even when the task has a hierarchical structure. However, with a connection cost, networks evolve to be both modular and hierarchical, and these networks exhibit higher overall performance and evolvability (i.e. faster adaptation to new environments). Additional analyses confirm that hierarchy independently improves adaptability after controlling for modularity. Overall, our results suggest that the same force–the cost of connections–promotes the evolution of both hierarchy and modularity, and that these properties are important drivers of network performance and adaptability. In addition to shedding light on the emergence of hierarchy across the many domains in which it appears, these findings will also accelerate future research into evolving more complex, intelligent computational brains in the fields of artificial intelligence and robotics. PMID:27280881

The Evolutionary Origins of Hierarchy.

Directory of Open Access Journals (Sweden)

Henok Mengistu

2016-06-01

Full Text Available Hierarchical organization-the recursive composition of sub-modules-is ubiquitous in biological networks, including neural, metabolic, ecological, and genetic regulatory networks, and in human-made systems, such as large organizations and the Internet. To date, most research on hierarchy in networks has been limited to quantifying this property. However, an open, important question in evolutionary biology is why hierarchical organization evolves in the first place. It has recently been shown that modularity evolves because of the presence of a cost for network connections. Here we investigate whether such connection costs also tend to cause a hierarchical organization of such modules. In computational simulations, we find that networks without a connection cost do not evolve to be hierarchical, even when the task has a hierarchical structure. However, with a connection cost, networks evolve to be both modular and hierarchical, and these networks exhibit higher overall performance and evolvability (i.e. faster adaptation to new environments. Additional analyses confirm that hierarchy independently improves adaptability after controlling for modularity. Overall, our results suggest that the same force-the cost of connections-promotes the evolution of both hierarchy and modularity, and that these properties are important drivers of network performance and adaptability. In addition to shedding light on the emergence of hierarchy across the many domains in which it appears, these findings will also accelerate future research into evolving more complex, intelligent computational brains in the fields of artificial intelligence and robotics.

On the Hierarchy of Neutrino Masses

International Nuclear Information System (INIS)

Jezabek, M.; Urban, P.

2002-01-01

We present a model of neutrino masses combining the seesaw mechanism and strong Dirac mass hierarchy and at the same time exhibiting a significantly reduced hierarchy at the level of active neutrino masses. The heavy Majorana masses are assumed to be degenerate. The suppression of the hierarchy is due to a symmetric and unitary operator R whose role is discussed. The model gives realistic mixing and mass spectrum. The mixing of atmospheric neutrinos is attributed to the charged lepton sector whereas the mixing of solar neutrinos is due to the neutrino sector. Small U e3 is a consequence of the model. The masses of the active neutrinos are given by μ 3 ≅ √(Δm 2 O ) and μ 1 /μ 2 = ≅ tan 2 (θ O ). (author)

Program information architecture/document hierarchy

International Nuclear Information System (INIS)

Woods, T.W.

1991-09-01

The Nuclear Waste Management System (NWMS) Management Systems Improvement Strategy (MSIS) (DOE 1990) requires that the information within the computer program and information management system be ordered into a precedence hierarchy for consistency. Therefore, the US Department of Energy (DOE). Office of Civilian Radioactive Waste Management (OCRWM) requested Westinghouse Hanford Company to develop a plan for NWMS program information which the MSIS calls a document hierarchy. This report provides the results of that effort and describes the management system as a ''program information architecture.'' 3 refs., 3 figs

Riemann-Liouville integrals of fractional order and extended KP hierarchy

International Nuclear Information System (INIS)

Kamata, Masaru; Nakamula, Atsushi

2002-01-01

An attempt to formulate the extensions of the KP hierarchy by introducing fractional-order pseudo-differential operators is given. In the case of the extension with the half-order pseudo-differential operators, a system analogous to the supersymmetric extensions of the KP hierarchy is obtained. Unlike the supersymmetric extensions, no Grassmannian variable appears in the hierarchy considered here. More general hierarchies constructed by the 1/Nth-order pseudo-differential operators, their integrability and the reduction procedure are also investigated. In addition to finding the new extensions of the KP hierarchy, a brief introduction to the Riemann-Liouville integral is provided to yield a candidate for the fractional-order pseudo-differential operators

The Helmholtz Hierarchy: Phase Space Statistics of Cold Dark Matter

OpenAIRE

Tassev, Svetlin

2010-01-01

We present a new formalism to study large-scale structure in the universe. The result is a hierarchy (which we call the "Helmholtz Hierarchy") of equations describing the phase space statistics of cold dark matter (CDM). The hierarchy features a physical ordering parameter which interpolates between the Zel'dovich approximation and fully-fledged gravitational interactions. The results incorporate the effects of stream crossing. We show that the Helmholtz hierarchy is self-consistent and obeys...

Formal language theory: refining the Chomsky hierarchy

Science.gov (United States)

Jäger, Gerhard; Rogers, James

2012-01-01

The first part of this article gives a brief overview of the four levels of the Chomsky hierarchy, with a special emphasis on context-free and regular languages. It then recapitulates the arguments why neither regular nor context-free grammar is sufficiently expressive to capture all phenomena in the natural language syntax. In the second part, two refinements of the Chomsky hierarchy are reviewed, which are both relevant to the extant research in cognitive science: the mildly context-sensitive languages (which are located between context-free and context-sensitive languages), and the sub-regular hierarchy (which distinguishes several levels of complexity within the class of regular languages). PMID:22688632

Formal language theory: refining the Chomsky hierarchy.

Science.gov (United States)

Jäger, Gerhard; Rogers, James

2012-07-19

The first part of this article gives a brief overview of the four levels of the Chomsky hierarchy, with a special emphasis on context-free and regular languages. It then recapitulates the arguments why neither regular nor context-free grammar is sufficiently expressive to capture all phenomena in the natural language syntax. In the second part, two refinements of the Chomsky hierarchy are reviewed, which are both relevant to the extant research in cognitive science: the mildly context-sensitive languages (which are located between context-free and context-sensitive languages), and the sub-regular hierarchy (which distinguishes several levels of complexity within the class of regular languages).

SUSY-hierarchy of one-dimensional reflectionless potentials

International Nuclear Information System (INIS)

Maydanyuk, Sergei P.

2005-01-01

A class of one-dimensional reflectionless potentials is studied. It is found that all possible types of the reflectionless potentials can be combined into one SUSY-hierarchy with a constant potential. An approach for determination of a general form of the reflectionless potential on the basis of construction of such a hierarchy by the recurrent method is proposed. A general integral form of interdependence between superpotentials with neighboring numbers of this hierarchy, opening a possibility to find new reflectionless potentials, is found and has a simple analytical view. It is supposed that any possible type of the reflectionless potential can be expressed through finite number of elementary functions (unlike some presentations of the reflectionless potentials, which are constructed on the basis of soliton solutions or are shape invariant in one or many steps with involving scaling of parameters, and are expressed through series). An analysis of absolute transparency existence for the potential which has the inverse power dependence on space coordinate (and here tunneling is possible), i.e., which has the form V (x) = ± α/ vertical bar x-x 0 vertical bar n (where α and x 0 are constants, n is natural number), is fulfilled. It is shown that such a potential can be reflectionless at n = 2 only. A SUSY-hierarchy of the inverse power reflectionless potentials is constructed. Isospectral expansions of this hierarchy are analyzed

Boltzmann hierarchy for interacting neutrinos I: formalism

International Nuclear Information System (INIS)

Oldengott, Isabel M.; Rampf, Cornelius; Wong, Yvonne Y.Y.

2015-01-01

Starting from the collisional Boltzmann equation, we derive for the first time and from first principles the Boltzmann hierarchy for neutrinos including interactions with a scalar particle. Such interactions appear, for example, in majoron-like models of neutrino mass generation. We study two limits of the scalar mass: (i) An extremely massive scalar whose only role is to mediate an effective 4-fermion neutrino-neutrino interaction, and (ii) a massless scalar that can be produced in abundance and thus demands its own Boltzmann hierarchy. In contrast to, e.g., the first-order Boltzmann hierarchy for Thomson-scattering photons, our interacting neutrino/scalar Boltzmann hierarchies contain additional momentum-dependent collision terms arising from a non-negligible energy transfer in the neutrino-neutrino and neutrino-scalar interactions. This necessitates that we track each momentum mode of the phase space distributions individually, even if the particles were massless. Comparing our hierarchy with the commonly used (c eff 2 ,c vis 2 )-parameterisation, we find no formal correspondence between the two approaches, which raises the question of whether the latter parameterisation even has an interpretation in terms of particle scattering. Lastly, although we have invoked majoron-like models as a motivation for our study, our treatment is in fact generally applicable to all scenarios in which the neutrino and/or other ultrarelativistic fermions interact with scalar particles

Virasoro algebra action on integrable hierarchies and Virasoro contraints in matrix models

International Nuclear Information System (INIS)

Semikhatov, A.M.

1991-01-01

The action of the Virasoro algebra on integrable hierarchies of non-linear equations and on related objects ('Schroedinger' differential operators) is investigated. The method consists in pushing forward the Virasoro action to the wave function of a hierarchy, and then reconstructing its action on the dressing and Lax operators. This formulation allows one to observe a number of suggestive similarities between the structures involved in the description of the Virasoro algebra on the hierarchies and the structure of conformal field theory on the world-sheet. This includes, in particular, an 'off-shell' hierarchy version of operator products and of the Cauchy kernel. In relation to matrix models, which have been observed to be effectively described by integrable hierarchies subjected to Virasoro constraints, I propose to define general Virasoro-constrained hierarchies also in terms of dressing operators, by certain equations which carry the information of the hierarchy and the Virasoro algebra simultaneously and which suggest an interpretation as operator versions of recursion/loop equations in topological theories. These same equations provide a relation with integrable hierarchies with quantized spectral parameter introduced recently. The formulation in terms of dressing operators allows a scaling (continuum limit) of discrete (i.e. lattice) hierarchies with the Virasoro constraints into 'continuous' Virasoro-constrained hierarchies. In particular, the KP hierarchy subjected to the Virasoro constraints is recovered as a scaling limit of the Virasoro-constrained Toda hierarchy. The dressing operator method also makes is straightforward to identify the full symmetry algebra of Virasoro-constrained hierarchies, which is related to the family of W ∞ (J) algebras introduced recently. (orig./HS)

Sexualidad violenta en el cine de Kim Ki-duk

Directory of Open Access Journals (Sweden)

Daniel Muñoz Ruiz

2011-07-01

Full Text Available En sus más de 110 años de vida el cine ha representado la sexualidad humana en todas sus modalidades y desde los más variados puntos de vista. El cine de Kim Ki-duk ha sorprendido y escandalizado al público por su crudeza y, a veces, excesiva violencia. El director surcoreano ha explorado a lo largo de su filmografía el tema del sexo siempre desde puntos de vista dramáticos y hasta truculentos. En sus películas la mayoría de las relaciones sexuales carecen de amor y afecto. Nunca son placenteras. La violación, la prostitución, la violencia de género y las frustraciones sexuales son temas recurrentes en su cine.

A hierarchy of Ramsey-like cardinals

OpenAIRE

Holy, Peter; Schlicht, Philipp

2017-01-01

We introduce a hierarchy of large cardinals between weakly compact and measurable cardinals, that is closely related to the Ramsey-like cardinals introduced by Victoria Gitman, and is based on certain infinite filter games, however also has a range of equivalent characterizations in terms of elementary embeddings. The aim of this paper is to locate the Ramsey-like cardinals studied by Gitman, and other well-known large cardinal notions, in this hierarchy.

Hierarchy generation in compactified supersymmetric models

International Nuclear Information System (INIS)

Ross, G.G.

1988-01-01

The problem of generating a large hierarchy in compactified supersymmetric models is re-examined. It is shown how, even for the class of models for which Str M 2 is non-vanishing, a combination of non-perturbative effects and radiative corrections may lead to an exponentially large hierarchy. A corollary is that the couplings of the effective field theory in the visible sector should be small, i.e., perturbation theory should be applicable. (orig.)

The Toda lattice hierarchy and deformation of conformal field theories

International Nuclear Information System (INIS)

Fukuma, M.

1990-01-01

In this paper, the authors point out that the Toda lattice hierarchy known in soliton theory is relevant for the description of the deformations of conformal field theories while the KP hierarchy describes unperturbed conformal theories. It is shown that the holomorphic parts of the conserved currents in the perturbed system (the Toda lattice hierarchy) coincide with the conserved currents in the KP hierarchy and can be written in terms of the W-algebraic currents. Furthermore, their anti-holomorphic counterparts are obtained

A multi-component matrix loop algebra and a unified expression of the multi-component AKNS hierarchy and the multi-component BPT hierarchy

International Nuclear Information System (INIS)

Zhang Yufeng

2005-01-01

A set of multi-component matrix Lie algebra is constructed, which is devote to obtaining a new loop algebra A-bar M-1 . It follows that an isospectral problem is established. By making use of Tu scheme, a Liouville integrable multi-component hierarchy of soliton equations is generated, which possesses the bi-Hamiltonian structures. As its reduction cases, the multi-component AKNS hierarchy and the formalism of the multi-component BPT hierarchy are given, respectively

Objective Bayesian analysis of neutrino masses and hierarchy

Science.gov (United States)

Heavens, Alan F.; Sellentin, Elena

2018-04-01

Given the precision of current neutrino data, priors still impact noticeably the constraints on neutrino masses and their hierarchy. To avoid our understanding of neutrinos being driven by prior assumptions, we construct a prior that is mathematically minimally informative. Using the constructed uninformative prior, we find that the normal hierarchy is favoured but with inconclusive posterior odds of 5.1:1. Better data is hence needed before the neutrino masses and their hierarchy can be well constrained. We find that the next decade of cosmological data should provide conclusive evidence if the normal hierarchy with negligible minimum mass is correct, and if the uncertainty in the sum of neutrino masses drops below 0.025 eV. On the other hand, if neutrinos obey the inverted hierarchy, achieving strong evidence will be difficult with the same uncertainties. Our uninformative prior was constructed from principles of the Objective Bayesian approach. The prior is called a reference prior and is minimally informative in the specific sense that the information gain after collection of data is maximised. The prior is computed for the combination of neutrino oscillation data and cosmological data and still applies if the data improve.

Quark mass hierarchies from the universal seesaw mechanism

International Nuclear Information System (INIS)

Davidson, A.; Michel, L.; Sage, M.L.; Wali, K.C.

1994-01-01

The paper is an extension of the previous work based on the idea of a universal seesaw mechanism to explain the hierarchies in the fermion mass spectrum. A model is proposed within the framework of left-right symmetry with a minimal Higgs system and an axial U(1) symmetry imposed to distinguish the generations. Previous work was confined, for mathematical simplifications, to the case of nonsingular mass matrices. In the present paper, singular matrices are considered. A systematic perturbative technique is developed to display the mass eigenvalues in terms of the vacuum expectation values of the assumed Higgs multiplets. The model successfully correlates the mass hierarchies among the quarks to the assumed hierarchies in the vacuum expectation values without appealing to a hierarchy in the Yukawa-type fermion--Higgs-boson couplings. By considering a general Higgs potential appropriate to the model, we study its minimization and prove that there exists an open subdomain in the parameter space where the orbit of the lowest minima of the potential corresponds to the kind of hierarchy in the vacuum expectation values needed for the success of the model

Hermitian versus anti-hermitian one-matrix models and their hierarchies

International Nuclear Information System (INIS)

Hollowood, T.; Miramontes, L.; Pasquinucci, A.; Nappi, C.

1992-01-01

Building on a recent work of C. Crnkovic, M. Douglas and G. Moore, a study of multi-critical multi-cut one-matrix models and their associated sl(2, C) integrable hierarchies, is further pursued. The double-scaling limits of hermitian matrix models with different scaling ansaetze, lead to the KdV hierarchy, to the modified KdV hierarchy and part of the non-linear Schroedinger hierarchy. Instead, the anti-hermitian matrix model, in the 2-arc sector, results in the Zakharov-Shabat hierarchy, which contains both KdV and mKdV as reductions. For all the hierarchies it is found that the Virasoro constraints act on the associated τ-functions. Whereas it is known that the ZS and KdV models lead to the Virasoro constraints of an sl(2, C) vacuum, we find that the mKdV model leads to the Virasoro constraints of a highest-weight state with arbitrary conformal dimension. (orig.)

Neutrino mass hierarchy determination for θ13 = 0

International Nuclear Information System (INIS)

Gandhi, Raj; Ghoshal, Pomita; Goswami, Srubabati; Sankar, S. Uma

2010-01-01

We examine the possibility of determining the neutrino mass hierarchy in the limit θ 13 = 0 using atmospheric neutrinos as the source. In this limit, θ 13 driven matter effects are absent so independent measurements of Δ 31 and Δ 32 can, in principle, lead to hierarchy determination. Since their difference is Δ 21 , one needs an experimental arrangement where Δ 21 L/E > or approx. 1 can be achieved. This can be satisfied by atmospheric neutrinos which have a large range of L and E. Still, we find that hierarchy determination in the θ 13 = 0 limit with atmospheric neutrinos is not a realistic possibility, even in conjunction with a beam experiment like T2K or NOνA. We discuss why, and also reiterate the general conditions for hierarchy determination if θ 13 = 0.

On the origins of hierarchy in complex networks

Science.gov (United States)

Corominas-Murtra, Bernat; Goñi, Joaquín; Solé, Ricard V.; Rodríguez-Caso, Carlos

2013-01-01

Hierarchy seems to pervade complexity in both living and artificial systems. Despite its relevance, no general theory that captures all features of hierarchy and its origins has been proposed yet. Here we present a formal approach resulting from the convergence of theoretical morphology and network theory that allows constructing a 3D morphospace of hierarchies and hence comparing the hierarchical organization of ecological, cellular, technological, and social networks. Embedded within large voids in the morphospace of all possible hierarchies, four major groups are identified. Two of them match the expected from random networks with similar connectivity, thus suggesting that nonadaptive factors are at work. Ecological and gene networks define the other two, indicating that their topological order is the result of functional constraints. These results are consistent with an exploration of the morphospace, using in silico evolved networks. PMID:23898177

Cohesion and Hierarchy in Physically Abusive Families

Directory of Open Access Journals (Sweden)

Clarissa De Antoni

2009-06-01

Full Text Available This paper investigates cohesion (emotional bonding and hierarchy (powerstructure in families with abuse against their children. Twenty low-incomefamilies participated. Father, mother and child’s perspective of family relations(cohesion and hierarchy were evaluated by the Family System Test(FAST. The relationship between father-child, mother-child, couple, andamong siblings were evaluated at typical and conflictive situations. Resultsshow a significance regarding to cohesion in typical and conflictive situationfor father-child and mother-child dyads in all perspectives (by father, mother,and child. There is no significant differences regarding to hierarchy. Theseresults suggest that the families see the intrafamilial violence as a constant,since they cannot differentiate between both situations.

The Hierarchy of Segment Reports

Directory of Open Access Journals (Sweden)

Danilo Dorović

2015-05-01

Full Text Available The article presents an attempt to find the connection between reports created for managers responsible for different business segments. With this purpose, the hierarchy of the business reporting segments is proposed. This can lead to better understanding of the expenses under common responsibility of more than one manager since these expenses should be in more than one report. The structure of cost defined per business segment hierarchy with the aim of new, unusual but relevant cost structure for management can be established. Both could potentially bring new information benefits for management in the context of profit reporting.

Children on Social Media, Twiter and Facebook (profile of Beyonce and Kim Kardashian

Directory of Open Access Journals (Sweden)

Anamarija Bilan

2017-09-01

Full Text Available Publishing children’s photos in the media violates their privacy right, which is protected, guaranteed and regulated by numerous international and Croatian laws and regulations. Likewise, publishing photos of children on social network profiles, such as Facebook or Twitter, violates the right to privacy. In this paper it will be researched the extent to which children’s photos are being disclosed and their privacy is being undermined in case of two Facebook and two Twitter profiles - Beyonce Knowles and Kim Kardashian. It will also research whether children are used for business purposes, whether they are advertising some of their products or shows, and so on, with the photographs of children. The content analysis methodology analyzed the Facebook and Twitter profiles of two respondents in the period from January 1 to February 22, 2016, during which they published a total of 459 posts on profiles of both networks. The analysis found that the total number of “posts” shows a small number of photographs of children but also that those published by Kim Kardashian are often used to promote or promote some of the products or programs, which violates the privacy of children and increases the number “like”.

Decomposition of a hierarchy of nonlinear evolution equations

International Nuclear Information System (INIS)

Geng Xianguo

2003-01-01

The generalized Hamiltonian structures for a hierarchy of nonlinear evolution equations are established with the aid of the trace identity. Using the nonlinearization approach, the hierarchy of nonlinear evolution equations is decomposed into a class of new finite-dimensional Hamiltonian systems. The generating function of integrals and their generator are presented, based on which the finite-dimensional Hamiltonian systems are proved to be completely integrable in the Liouville sense. As an application, solutions for the hierarchy of nonlinear evolution equations are reduced to solving the compatible Hamiltonian systems of ordinary differential equations

Boolean Operations, Joins, and the Extended Low Hierarchy

OpenAIRE

Hemaspaandra, Lane A.; Jiang, Zhigen; Rothe, Joerg; Watanabe, Osamu

1999-01-01

We prove that the join of two sets may actually fall into a lower level of the extended low hierarchy than either of the sets. In particular, there exist sets that are not in the second level of the extended low hierarchy, EL_2, yet their join is in EL_2. That is, in terms of extended lowness, the join operator can lower complexity. Since in a strong intuitive sense the join does not lower complexity, our result suggests that the extended low hierarchy is unnatural as a complexity measure. We...

Comparative steady-state pharmacokinetic study of an extended-release formulation of itopride and its immediate-release reference formulation in healthy volunteers

OpenAIRE

Yoon, Seonghae; Lee, Howard; Kim, Tae-Eun; Lee, SeungHwan; Chee, Dong-Hyun; Cho, Joo-Youn; Yu, Kyung-Sang; Jang, In-Jin

2014-01-01

Seonghae Yoon,1,* Howard Lee,2,* Tae-Eun Kim,1 SeungHwan Lee,1 Dong-Hyun Chee,3 Joo-Youn Cho,1 Kyung-Sang Yu,1 In-Jin Jang1 1Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, 2Clinical Trials Center, Seoul National University Hospital, 3AbbVie Ltd., Seoul, Republic of Korea *These authors contributed equally to this work Background: This study was conducted to compare the oral bioavailability of an itopride extended-release (ER...

Latent class analysis on internet and smartphone addiction in college students

OpenAIRE

Mok, Jung-Yeon; Choi, Sam-Wook; Kim, Dai-Jin; Choi, Jung-Seok; Lee, Jaewon; Ahn, Heejune; Choi, Eun-Jeung; Song, Won-Young

2014-01-01

Jung-Yeon Mok,1 Sam-Wook Choi,1,2 Dai-Jin Kim,3 Jung-Seok Choi,4 Jaewon Lee,2 Heejune Ahn,5 Eun-Jeung Choi,6 Won-Young Song7 1Eulji Addiction Institute, Eulji University, Seoul, South Korea; 2Department of Psychiatry, Gangnam Eulji Hospital, Eulji University, Seoul, South Korea; 3Department of Psychiatry, Seoul St Mary's Hospital, College of Medicine, Catholic University of Korea, Seoul, South Korea; 4Department of Psychiatry, SMG-SNU Boramae Medical Center, Seoul, South Korea; 5Depar...

Targeting Biological Sensing with Commercial SERS Substrates

Science.gov (United States)

2012-09-01

substrate substrate. Sl x 4 mm waf urement to re ossible contam substrates, fiv resented as an e being used f tigated, and nam eived in an ac cations...targeted nanotechnology-based inhalation co-delivery of anticancer drugs and siRNA," Journal of Drug Targeting, 900-914 (2011). [35] Jong , H.J., Na...J.H., Jin, B.S., Lee, W.K., Lee, W.H., Jung, H.J., Kim , S.C., Lim, S.H., Yu, Y.G., "Identification of Dinitrotoluene Selective Peptides by Phage

Coupling Integrable Couplings of an Equation Hierarchy

International Nuclear Information System (INIS)

Wang Hui; Xia Tie-Cheng

2013-01-01

Based on a kind of Lie algebra G proposed by Zhang, one isospectral problem is designed. Under the framework of zero curvature equation, a new kind of integrable coupling of an equation hierarchy is generated using the methods proposed by Ma and Gao. With the help of variational identity, we get the Hamiltonian structure of the hierarchy. (general)

A study on the hierarchy model of nuclear reactions

International Nuclear Information System (INIS)

Kitazoe, Yasuhiro; Sekiya, Tamotsu

1975-01-01

The application of the hierarchy model of nuclear reaction is discussed, and the hierarchy model means that the compound nucleus state is formed after several steps, at least, one step of reaction. This model was applied to the analysis of the observed cross sections of 235 U and some other elements. Neglecting exchange scattering effect, the equations for the total neutron cross section of 235 U were obtained. One of these equations describes explicitly the hierarchy of the transition from intermediate reaction state Xm into the compound nucleus state Xs, and another one describes the cross section averaged over an energy interval larger than the average level spacing of compound nucleus eigenvalues. The hierarchy of reaction mechanism was investigated in more detail, and the hierarchy model was applied to the case of unresolved energy region. It was not tried to evaluate the strength function in the mass region (A>140), since the effect of nuclear deformation was neglected in the task. (Iwase, T.)

Self-organizing dominance hierarchies in a wild primate population

OpenAIRE

Franz, Mathias; McLean, Emily; Tung, Jenny; Altmann, Jeanne; Alberts, Susan C.

2015-01-01

Linear dominance hierarchies, which are common in social animals, can profoundly influence access to limited resources, reproductive opportunities and health. In spite of their importance, the mechanisms that govern the dynamics of such hierarchies remain unclear. Two hypotheses explain how linear hierarchies might emerge and change over time. The ‘prior attributes hypothesis’ posits that individual differences in fighting ability directly determine dominance ranks. By contrast, the ‘social d...

A unified expressing model of the AKNS hierarchy and the KN hierarchy, as well as its integrable coupling system

International Nuclear Information System (INIS)

Guo Fukui; Zhang Yufeng

2004-01-01

A new subalgebra of loop algebra A-tilde 1 is first constructed. Then a new Lax pair is presented, whose compatibility gives rise to a new Liouville integrable system(called a major result), possessing bi-Hamiltonian structures. It is remarkable that two symplectic operators obtained in this paper are directly constructed in terms of the recurrence relations. As reduction cases of the new integrable system obtained, the famous AKNS hierarchy and the KN hierarchy are obtained, respectively. Second, we prove a conjugate operator of a recurrence operator is a hereditary symmetry. Finally, we construct a high dimension loop algebra G-bar to obtain an integrable coupling system of the major result by making use of Tu scheme. In addition, we find the major result obtained is a unified expressing integrable model of both the AKNS and KN hierarchies, of course, we may also regard the major result as an expanding integrable model of the AKNS and KN hierarchies. Thus, we succeed to find an example of expanding integrable models being Liouville integrable

Eye Movement Evidence for Hierarchy Effects on Memory Representation of Discourses.

Directory of Open Access Journals (Sweden)

Yingying Wu

Full Text Available In this study, we applied the text-change paradigm to investigate whether and how discourse hierarchy affected the memory representation of a discourse. Three kinds of three-sentence discourses were constructed. In the hierarchy-high condition and the hierarchy-low condition, the three sentences of the discourses were hierarchically organized and the last sentence of each discourse was located at the high level and the low level of the discourse hierarchy, respectively. In the linear condition, the three sentences of the discourses were linearly organized. Critical words were always located at the last sentence of the discourses. These discourses were successively presented twice and the critical words were changed to semantically related words in the second presentation. The results showed that during the early processing stage, the critical words were read for longer times when they were changed in the hierarchy-high and the linear conditions, but not in the hierarchy-low condition. During the late processing stage, the changed-critical words were again found to induce longer reading times only when they were in the hierarchy-high condition. These results suggest that words in a discourse have better memory representation when they are located at the higher rather than at the lower level of the discourse hierarchy. Global discourse hierarchy is established as an important factor in constructing the mental representation of a discourse.

Eye Movement Evidence for Hierarchy Effects on Memory Representation of Discourses.

Science.gov (United States)

Wu, Yingying; Yang, Xiaohong; Yang, Yufang

2016-01-01

In this study, we applied the text-change paradigm to investigate whether and how discourse hierarchy affected the memory representation of a discourse. Three kinds of three-sentence discourses were constructed. In the hierarchy-high condition and the hierarchy-low condition, the three sentences of the discourses were hierarchically organized and the last sentence of each discourse was located at the high level and the low level of the discourse hierarchy, respectively. In the linear condition, the three sentences of the discourses were linearly organized. Critical words were always located at the last sentence of the discourses. These discourses were successively presented twice and the critical words were changed to semantically related words in the second presentation. The results showed that during the early processing stage, the critical words were read for longer times when they were changed in the hierarchy-high and the linear conditions, but not in the hierarchy-low condition. During the late processing stage, the changed-critical words were again found to induce longer reading times only when they were in the hierarchy-high condition. These results suggest that words in a discourse have better memory representation when they are located at the higher rather than at the lower level of the discourse hierarchy. Global discourse hierarchy is established as an important factor in constructing the mental representation of a discourse.

Hierarchy and social status in Budongo chimpanzees.

Science.gov (United States)

Newton-Fisher, Nicholas E

2004-04-01

The status hierarchy is fundamental in the lives of male chimpanzees. This study describes the dominance interactions and social status among adult male chimpanzees of the Sonso community in the Budongo Forest Reserve, Uganda, during the period that they were first studied (1994 and 1995). Social dominance is typically measured using the behaviour of either the subordinate or the dominant individual, but a relationship is dependent on the behaviour of both parties and this study explicitly used both subordinate and dominant behaviours to investigate the status hierarchy. Among adult males of the Sonso community, agonistic interactions occurred at a low rate and pant-grunts were rare, but males could be ranked into separate hierarchies of agonistic dominance and pant-grunting (labelled 'respect') using ratios of behaviour performed/behaviour received. These hierarchies were combined to form a single hierarchy of social status that divided the males among five distinct status levels. The highest status level was held by an alliance between two males who replaced the previous alpha male during the first part of the study. Neither male in this alliance partnership pant-grunted to the other, although the reason for cooperative behaviour was unclear. Although the nominally beta male was treated as such by other adult males, he achieved surprisingly little mating success. Budongo Forest chimpanzees do not warrant the sometimes-expressed view that they are non-aggressive and peaceable and the broad pattern of their status interactions matches with that seen in other chimpanzee populations.

Plasticity within stem cell hierarchies in mammalian epithelia.

Science.gov (United States)

Tetteh, Paul W; Farin, Henner F; Clevers, Hans

2015-02-01

Tissue homeostasis and regeneration are fueled by resident stem cells that have the capacity to self-renew, and to generate all the differentiated cell types that characterize a particular tissue. Classical models of such cellular hierarchies propose that commitment and differentiation occur unidirectionally, with the arrows 'pointing away' from the stem cell. Recent studies, all based on genetic lineage tracing, describe various strategies employed by epithelial stem cell hierarchies to replace damaged or lost cells. While transdifferentiation from one tissue type into another ('metaplasia') appears to be generally forbidden in nonpathological contexts, plasticity within an individual tissue stem cell hierarchy may be much more common than previously appreciated. In this review, we discuss recent examples of such plasticity in selected mammalian epithelia, highlighting the different modes of regeneration and their implications for our understanding of cellular hierarchy and tissue self-renewal. Copyright © 2014 Elsevier Ltd. All rights reserved.

Ansatz for dynamical hierarchies

DEFF Research Database (Denmark)

Rasmussen, S.; Baas, N.A.; Mayer, B.

2001-01-01

Complex, robust functionalities can be generated naturally in at least two ways: by the assembly of structures and by the evolution of structures. This work is concerned with spontaneous formation of structures. We define the notion of dynamical hierarchies in natural systems and show...... the importance of this particular kind of organization for living systems. We then define a framework that enables us to formulate, investigate, and manipulate such dynamical hierarchies. This framework allows us to simultaneously investigate different levels of description together with them interrelationship...... three. Formulating this system as a simple two-dimensional molecular dynamics (MD) lattice gas allows us within one dynamical system to demonstrate the successive emergence of two higher levels (three levels all together) of robust structures with associated properties. Second, we demonstrate how...

The Impact of Formal Hierarchies on Enterprise Social Networking Behavior

DEFF Research Database (Denmark)

Behrendt, Sebastian; Klier, Julia; Klier, Mathias

2015-01-01

With more and more companies using enterprise social networks (ESN) for employee communication and collaboration, the influence of ESN on organizational hierarchies has been subject of countless discussions in practice-oriented media and first academic studies. Conversely, the question whether...... and how formal organizational hierarchies influence ESN usage behavior has not yet been addressed. Drawing on a rich data set comprising 2.5 years of relationship building via direct messages, confirmed contact requests, and group messages, we are able to show that formal hierarchies have an important...... impact on social networking behavior. By applying means of social network analysis and supported by statements from interviews, we illustrate how deeply formal hierarchy impacts the three examined types of relationships. Our results motivate academics to further study the interrelation between hierarchy...

Hierarchies of multi-component mKP equations and theirs integrable couplings

International Nuclear Information System (INIS)

Ji Jie; Yao Yuqin; Zhu Fubo; Chen Dengyuan

2008-01-01

First, a new multi-component modified Kadomtsev-Petviashvill (mKP) spectral problem is constructed by k-constraint imposed on a general pseudo-differential operator. Then, two hierarchies of multi-component mKP equations are derived, including positive non-isospectral mKP hierarchy and negative non-isospectral mKP hierarchy. Moreover, new integrable couplings of the resulting mKP soliton hierarchies are constructed by enlarging the associated matrix spectral problem

Hierarchy among Automata on Linear Orderings

OpenAIRE

Bruyère , Véronique; Carton , Olivier

2005-01-01

In a preceding paper, automata and rational expressions have been introduced for words indexed by linear orderings, together with a Kleene-like theorem. We here pursue this work by proposing a hierarchy among the rational sets. Each class of the hierarchy is defined by a subset of the rational operations that can be used. We then characterize any class by an appropriate class of automata, leading to a Kleene theorem inside the class. A characterization by particular classes of orderings is al...

Shrinking population and the urban hierarchy

OpenAIRE

Kim, Ho Yeon

2012-01-01

This paper examines whether population shrinkage leads to changes in the urban hierarchy in terms of relative sizes of cities and their functions onomic geography. We work backwards in a racetrack economy with eight cities in a long-run equilibrium. Initial distribution of population is chosen to satisfy both the rank-size rule and central place hierarchy. We have a short-run equilibrium in which firms choose prices and consumers choose consumption taking the number of workers in each region ...

Inequality Matters : Classroom Status Hierarchy and Adolescents' Bullying

NARCIS (Netherlands)

Garandeau, Claire F.; Lee, Ihno A.; Salmivalli, Christina

2014-01-01

The natural emergence of status hierarchies in adolescent peer groups has long been assumed to help prevent future intragroup aggression. However, clear evidence of this beneficial influence is lacking. In fact, few studies have examined between-group differences in the degree of status hierarchy

Reappraising the functional implications of the primate visual anatomical hierarchy.

Science.gov (United States)

Hegdé, Jay; Felleman, Daniel J

2007-10-01

The primate visual system has been shown to be organized into an anatomical hierarchy by the application of a few principled criteria. It has been widely assumed that cortical visual processing is also hierarchical, with the anatomical hierarchy providing a defined substrate for clear levels of hierarchical function. A large body of empirical evidence seemed to support this assumption, including the general observations that functional properties of visual neurons grow progressively more complex at progressively higher levels of the anatomical hierarchy. However, a growing body of evidence, including recent direct experimental comparisons of functional properties at two or more levels of the anatomical hierarchy, indicates that visual processing neither is hierarchical nor parallels the anatomical hierarchy. Recent results also indicate that some of the pathways of visual information flow are not hierarchical, so that the anatomical hierarchy cannot be taken as a strict flowchart of visual information either. Thus, while the sustaining strength of the notion of hierarchical processing may be that it is rather simple, its fatal flaw is that it is overly simplistic.

Two hierarchies of multi-component Kaup-Newell equations and theirs integrable couplings

International Nuclear Information System (INIS)

Zhu Fubo; Ji Jie; Zhang Jianbin

2008-01-01

Two hierarchies of multi-component Kaup-Newell equations are derived from an arbitrary order matrix spectral problem, including positive non-isospectral Kaup-Newell hierarchy and negative non-isospectral Kaup-Newell hierarchy. Moreover, new integrable couplings of the resulting Kaup-Newell soliton hierarchies are constructed by enlarging the associated matrix spectral problem

A generalized AKNS hierarchy and its bi-Hamiltonian structures

International Nuclear Information System (INIS)

Xia Tiecheng; You Fucai; Chen Dengyuan

2005-01-01

First we construct a new isospectral problem with 8 potentials in the present paper. And then a new Lax pair is presented. By making use of Tu scheme, a class of new soliton hierarchy of equations is derived, which is integrable in the sense of Liouville and possesses bi-Hamiltonian structures. After making some reductions, the well-known AKNS hierarchy and other hierarchies of evolution equations are obtained. Finally, in order to illustrate that soliton hierarchy obtained in the paper possesses bi-Hamiltonian structures exactly, we prove that the linear combination of two-Hamiltonian operators admitted are also a Hamiltonian operator constantly. We point out that two Hamiltonian operators obtained of the system are directly derived from a recurrence relations, not from a recurrence operator

Wronskian type solutions for the vector k-constrained KP hierarchy

International Nuclear Information System (INIS)

Zhang Youjin.

1995-07-01

Motivated by a relation of the 1-constrained Kadomtsev-Petviashvili (KP) hierarchy with the 2 component KP hierarchy, the tau-conditions of the vector k-constrained KP hierarchy are constructed by using an analogue of the Baker-Akhiezer (m + 1)-point function. These tau functions are expressed in terms of Wronskian type determinants. (author). 20 refs

Clinical significance of NGAL and KIM-1 for acute kidney injury in patients with scrub typhus.

Science.gov (United States)

Sun, In O; Shin, Sung Hye; Cho, A Young; Yoon, Hyun Ju; Chang, Mi Yok; Lee, Kwang Young

2017-01-01

The aim of this study is to investigate the clinical significance of neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule-1 (KIM-1) for acute kidney injury (AKI) in patients with scrub typhus. From 2014 to 2015, 145 patients were diagnosed with scrub typhus. Of these, we enrolled 138 patients who were followed up until renal recovery or for at least 3 months. We measured serum and urine NGAL and KIM-1 levels and evaluated prognostic factors affecting scrub typhus-associated AKI. Of the 138 patients, 25 had scrub typhus-associated AKI. The incidence of AKI was 18.1%; of which 11.6%, 4.3%, and 2.2% were classified as risk, injury, and failure, respectively, according to RIFLE criteria. Compared with patients in the non-AKI group, patients in the AKI group were older and showed higher total leukocyte counts and hypoalbuminemia or one or more comorbidities such as hypertension (72% vs 33%, pscrub typhus-associated AKI.

〈査読付論文〉The Necessity to Advance Disclosing Fair Value by the Hierarchy: Evidence from Literature Review about Fair Value Hierarchy Information

OpenAIRE

ZHANG, JIAO

2016-01-01

[Abstract]This paper aims to discuss the necessity to advance disclosing fair value by hierarchy in Japan by reviewing the literature about fair value hierarchy information in the U.S.　In Japan, ASBJ published the Exposure Draft "Accounting Standards on Fair Value Measurement and Disclosure" in 2010 which specifies that the fair value should be reported by hierarchy.　However, it has not published as formal standard until March 2016.　Furthermore, some commenters suggested that the hierarchy an...

The Development of Hierarchy of Effects Model in Advertising

Directory of Open Access Journals (Sweden)

Bambang Sukma Wijaya

2012-04-01

Full Text Available This paper aims to review the hierarchy of effects models in advertising, especially the well-known model, AIDA (Attention, Interest, Desire, and Action. Since its introduction by Lewis (1900 and generally attributed in the marketing and advertising literature by Strong (1925, the concept of AIDA’s hierarchy of effects model has been used by many researchers, both academicians and practitioners. The model is used to measure the effect of an advertisement. However, the development of information technology has radically changed the way of how people communicate and socialize; as well as a paradigm shift from product-oriented marketing to consumer-oriented marketing or people-oriented marketing. Therefore, the variables in the hierarchy of effects model needs to be updated in respond to the latest developments in the notice of public power as consumer audience. Based on deep literature review and reflective method, this paper introduces a new developed concept of hierarchy of effects model that was adopted from AIDA’s hierarchy of effects model, namely: AISDALSLove (At-tention, Interest, Search, Desire, Action, Like/dislike, Share, and Love/hate.

A Misleading Review of Response Bias: Comment on McGrath, Mitchell, Kim, and Hough (2010)

Science.gov (United States)

Rohling, Martin L.; Larrabee, Glenn J.; Greiffenstein, Manfred F.; Ben-Porath, Yossef S.; Lees-Haley, Paul; Green, Paul; Greve, Kevin W.

2011-01-01

In the May 2010 issue of "Psychological Bulletin," R. E. McGrath, M. Mitchell, B. H. Kim, and L. Hough published an article entitled "Evidence for Response Bias as a Source of Error Variance in Applied Assessment" (pp. 450-470). They argued that response bias indicators used in a variety of settings typically have insufficient data to support such…

Do experiments suggest a hierarchy problem?

International Nuclear Information System (INIS)

Vissani, F.

1997-09-01

The hierarchy problem of the scalar sector of the standard model is reformulated, emphasizing the role of experimental facts that may suggest the existence of a new physics large mass scale, for instance indications of the instability of the matter, or indications in favor of massive neutrinos. In the see-saw model for the neutrino masses a hierarchy problem arises if the mass of the right-handed neutrinos is larger than approximatively 10 7 GeV: this problem, and its possible solutions, are discussed. (author)

Comparing the Hierarchy of Keywords in On-Line News Portals.

Science.gov (United States)

Tibély, Gergely; Sousa-Rodrigues, David; Pollner, Péter; Palla, Gergely

2016-01-01

Hierarchical organization is prevalent in networks representing a wide range of systems in nature and society. An important example is given by the tag hierarchies extracted from large on-line data repositories such as scientific publication archives, file sharing portals, blogs, on-line news portals, etc. The tagging of the stored objects with informative keywords in such repositories has become very common, and in most cases the tags on a given item are free words chosen by the authors independently. Therefore, the relations among keywords appearing in an on-line data repository are unknown in general. However, in most cases the topics and concepts described by these keywords are forming a latent hierarchy, with the more general topics and categories at the top, and more specialized ones at the bottom. There are several algorithms available for deducing this hierarchy from the statistical features of the keywords. In the present work we apply a recent, co-occurrence-based tag hierarchy extraction method to sets of keywords obtained from four different on-line news portals. The resulting hierarchies show substantial differences not just in the topics rendered as important (being at the top of the hierarchy) or of less interest (categorized low in the hierarchy), but also in the underlying network structure. This reveals discrepancies between the plausible keyword association frameworks in the studied news portals.

Comparing the Hierarchy of Keywords in On-Line News Portals.

Directory of Open Access Journals (Sweden)

Gergely Tibély

Full Text Available Hierarchical organization is prevalent in networks representing a wide range of systems in nature and society. An important example is given by the tag hierarchies extracted from large on-line data repositories such as scientific publication archives, file sharing portals, blogs, on-line news portals, etc. The tagging of the stored objects with informative keywords in such repositories has become very common, and in most cases the tags on a given item are free words chosen by the authors independently. Therefore, the relations among keywords appearing in an on-line data repository are unknown in general. However, in most cases the topics and concepts described by these keywords are forming a latent hierarchy, with the more general topics and categories at the top, and more specialized ones at the bottom. There are several algorithms available for deducing this hierarchy from the statistical features of the keywords. In the present work we apply a recent, co-occurrence-based tag hierarchy extraction method to sets of keywords obtained from four different on-line news portals. The resulting hierarchies show substantial differences not just in the topics rendered as important (being at the top of the hierarchy or of less interest (categorized low in the hierarchy, but also in the underlying network structure. This reveals discrepancies between the plausible keyword association frameworks in the studied news portals.

An integrable coupling system of lattice hierarchy and its continuous limits

International Nuclear Information System (INIS)

Yu Fajun; Li Li

2009-01-01

In [E.G. Fan, Phys. Lett. A 372 (2008) 6368], Fan present a lattice hierarchy and its continuous limits. In this Letter, we extend this method, by introducing a complex discrete spectral problem, a coupling lattice hierarchy is derived. It is shown that a new sequence of combinations of complex lattice spectral problem converges to the integrable coupling couplings of soliton equation hierarchy, which has the integrable coupling system of AKNS hierarchy as a continuous limit.

A generalized Tu formula and Hamiltonian structures of fractional AKNS hierarchy

International Nuclear Information System (INIS)

Wu, Guo-cheng; Zhang, Sheng

2011-01-01

In this Letter, a generalized Tu formula is firstly presented to construct Hamiltonian structures of fractional soliton equations. The obtained results can be reduced to the classical Hamiltonian hierarchy of AKNS in ordinary calculus. -- Highlights: → A generalized Tu formula is first established based on the fractional variational theory for non-differentiable functions. → Hamiltonian structures of fractional AKNS hierarchy are obtained. → The classical AKNS hierarchy is just a special case of the fractional hierarchy.

A generalized Tu formula and Hamiltonian structures of fractional AKNS hierarchy

Energy Technology Data Exchange (ETDEWEB)

Wu, Guo-cheng, E-mail: wuguocheng2002@yahoo.com.cn [Key Laboratory of Numerical Simulation of Sichuan Province, Neijiang, Sichuan 641112 (China); College of Mathematics and Information Science, Neijiang Normal University, Neijiang, Sichuan 641112 (China); Zhang, Sheng, E-mail: zhshaeng@yahoo.com.cn [School of Mathematical Sciences, Dalian University of Technology, Dalian 116024 (China)

2011-10-03

In this Letter, a generalized Tu formula is firstly presented to construct Hamiltonian structures of fractional soliton equations. The obtained results can be reduced to the classical Hamiltonian hierarchy of AKNS in ordinary calculus. -- Highlights: → A generalized Tu formula is first established based on the fractional variational theory for non-differentiable functions. → Hamiltonian structures of fractional AKNS hierarchy are obtained. → The classical AKNS hierarchy is just a special case of the fractional hierarchy.

Continuous limits for an integrable coupling system of Toda equation hierarchy

International Nuclear Information System (INIS)

Li Li; Yu Fajun

2009-01-01

In this Letter, we present an integrable coupling system of lattice hierarchy and its continuous limits by using of Lie algebra sl(4). By introducing a complex discrete spectral problem, the integrable coupling system of Toda lattice hierarchy is derived. It is shown that a new complex lattice spectral problem converges to the integrable couplings of discrete soliton equation hierarchy, which has the integrable coupling system of C-KdV hierarchy as a new kind of continuous limit.

Continuous limits for an integrable coupling system of Toda equation hierarchy

Energy Technology Data Exchange (ETDEWEB)

Li Li [College of Maths and Systematic Science, Shenyang Normal University, Shenyang 110034 (China); Yu Fajun, E-mail: yfajun@163.co [College of Maths and Systematic Science, Shenyang Normal University, Shenyang 110034 (China)

2009-09-21

In this Letter, we present an integrable coupling system of lattice hierarchy and its continuous limits by using of Lie algebra sl(4). By introducing a complex discrete spectral problem, the integrable coupling system of Toda lattice hierarchy is derived. It is shown that a new complex lattice spectral problem converges to the integrable couplings of discrete soliton equation hierarchy, which has the integrable coupling system of C-KdV hierarchy as a new kind of continuous limit.

A generative model for scientific concept hierarchies.

Science.gov (United States)

Datta, Srayan; Adar, Eytan

2018-01-01

In many scientific disciplines, each new 'product' of research (method, finding, artifact, etc.) is often built upon previous findings-leading to extension and branching of scientific concepts over time. We aim to understand the evolution of scientific concepts by placing them in phylogenetic hierarchies where scientific keyphrases from a large, longitudinal academic corpora are used as a proxy of scientific concepts. These hierarchies exhibit various important properties, including power-law degree distribution, power-law component size distribution, existence of a giant component and less probability of extending an older concept. We present a generative model based on preferential attachment to simulate the graphical and temporal properties of these hierarchies which helps us understand the underlying process behind scientific concept evolution and may be useful in simulating and predicting scientific evolution.

A generative model for scientific concept hierarchies

Science.gov (United States)

Adar, Eytan

2018-01-01

In many scientific disciplines, each new ‘product’ of research (method, finding, artifact, etc.) is often built upon previous findings–leading to extension and branching of scientific concepts over time. We aim to understand the evolution of scientific concepts by placing them in phylogenetic hierarchies where scientific keyphrases from a large, longitudinal academic corpora are used as a proxy of scientific concepts. These hierarchies exhibit various important properties, including power-law degree distribution, power-law component size distribution, existence of a giant component and less probability of extending an older concept. We present a generative model based on preferential attachment to simulate the graphical and temporal properties of these hierarchies which helps us understand the underlying process behind scientific concept evolution and may be useful in simulating and predicting scientific evolution. PMID:29474409

New Nordic Exceptionalism: Jeuno JE Kim and Ewa Einhorn's The United Nations of Norden and other realist utopias

Directory of Open Access Journals (Sweden)

Mathias Danbolt

2016-11-01

Full Text Available At the 2009 Nordic Culture Forum summit in Berlin that centered on the profiling and branding of the Nordic region in a globalized world, one presenter stood out from the crowd. The lobbyist Annika Sigurdardottir delivered a speech that called for the establishment of “The United Nations of Norden”: A Nordic union that would gather the nations and restore Norden's role as the “moral superpower of the world.” Sigurdardottir's presentation generated such a heated debate that the organizers had to intervene and reveal that the speech was a performance made by the artists Jeuno JE Kim and Ewa Einhorn. This article takes Kim and Einhorn's intervention as a starting point for a critical discussion of the history and politics of Nordic image-building. The article suggests that the reason Kim and Einhorn's speech passed as a serious proposal was due to its meticulous mimicking of two discursive formations that have been central to the debates on the branding of Nordicity over the last decades: on the one hand, the discourse of “Nordic exceptionalism,” that since the 1960s has been central to the promotion of a Nordic political, socio-economic, and internationalist “third way” model, and, on the other hand, the discourse on the “New Nordic,” that emerged out of the New Nordic Food-movement in the early 2000s, and which has given art and culture a privileged role in the international re-fashioning of the Nordic brand. Through an analysis of Kim and Einhorn's United Nations of Norden (UNN-performance, the article examines the historical development and ideological underpinnings of the image of Nordic unity at play in the discourses of Nordic exceptionalism and the New Nordic. By focusing on how the UNN-project puts pressure on the role of utopian imaginaries in the construction of Nordic self-images, the article describes the emergence of a discursive framework of New Nordic Exceptionalism.

Explicit flow equations and recursion operator of the ncKP hierarchy

International Nuclear Information System (INIS)

He, Jingsong; Wang, Lihong; Tu, Junyi; Li, Xiaodong

2011-01-01

The explicit expression of the flow equations of the noncommutative Kadomtsev–Petviashvili (ncKP) hierarchy is derived. Compared with the flow equations of the KP hierarchy, our result shows that the additional terms in the flow equations of the ncKP hierarchy indeed consist of commutators of dynamical coordinates {u i }. The recursion operator for the flow equations under n-reduction is presented. Further, under 2-reduction, we calculate a nonlocal recursion operator Φ(2) of the noncommutative Korteweg–de Vries(ncKdV) hierarchy, which generates a hierarchy of local, higher-order flows. Thus we solve the open problem proposed by Olver and Sokolov (1998 Commun. Math. Phys. 193 245–68)

Implications of nonzero θ13 for the neutrino mass hierarchy

International Nuclear Information System (INIS)

Ernst, D J; Cogswell, B K; Burroughs, H R; Escamilla-Roa, J; Latimer, D C

2012-01-01

The Daya Bay, RENO, and Double Chooz experiments have discovered a large non-zero value for θ 13 . We present a global analysis that includes these three experiments, Chooz, the Super-K atmospheric data, and the ν μ → ν e T2K and MINOS experiments that are sensitive to the hierarchy and the sign of θ 13 . We report preliminary results in which we fix the mixing parameters other than θ 13 to those from a recent global analysis. Given there is no evidence for a non-zero CP violation, we assume δ = 0. T2K and MINOS lie in a region of L/E where there is a hierarchy degeneracy in the limit of θ 13 → 0 and no matter interaction. For nonzero θ 13 , the symmetry is partially broken, but a degeneracy under the simultaneous exchange of both hierarchy and the sign of θ 13 remains. Matter effects break this symmetry such that the positions of the peaks in the oscillation probabilities maintain the two-fold symmetry, while the magnitude of the oscillations is sensitive to the hierarchy. This renders T2K and NOvA, with different baselines and different matter effects, better able in combination to distinguish the hierarchy and the sign of θ 13 . The present T2K and MINOS data do not distinguish between hierarchies or the sign of θ 13 , but the large value of θ 13 yields effects from atmospheric data that do. We find for normal hierarchy, positive θ 13 , sin 2 2θ 13 = 0.090 ± 0.020 and is 0.2% probable it is the correct combination; for normal hierarchy, negative θ 13 , sin 2 2θ 13 = 0.108 ± 0.023 and is 2.2% probable; for inverse hierarchy, positive θ 13 , sin 2 2θ 13 = 0.110±0.022 and is 7.1% probable; for inverse hierarchy, negative θ 13 , sin 2 2θ 13 = 0.113 ± 0.022 and is 90.5% probable, results that are inconsistent with two similar analyses.

Two hierarchies of integrable lattice equations associated with a discrete matrix spectral problem

International Nuclear Information System (INIS)

Li Xinyue; Xu Xixiang; Zhao Qiulan

2008-01-01

Two hierarchies of nonlinear integrable positive and negative lattice models are derived from a discrete spectral problem. The two lattice hierarchies are proved to have discrete zero curvature representations associated with a discrete spectral problem, which also shows that the positive and negative hierarchies correspond to positive and negative power expansions of Lax operators with respect to the spectral parameter, respectively. Moreover, the integrable lattice models in the positive hierarchy are of polynomial type, and the integrable lattice models in the negative hierarchy are of rational type. Further, we construct infinite conservation laws of the positive hierarchy, then, the integrable coupling systems of the positive hierarchy are derived from enlarging Lax pair

Variable-coefficient nonisospectral Toda lattice hierarchy and its

Indian Academy of Sciences (India)

In this paper, a hierarchy of nonisospectral equations with variable coefficients is derived from the compatibility condition of Toda spectral problem and its time evolution. In order to solve the derived Toda lattice hierarchy, the inverse scattering transformation is utilized. As a result, new and more general exact solutions are ...

Hierarchy Measure for Complex Networks

Science.gov (United States)

Mones, Enys; Vicsek, Lilla; Vicsek, Tamás

2012-01-01

Nature, technology and society are full of complexity arising from the intricate web of the interactions among the units of the related systems (e.g., proteins, computers, people). Consequently, one of the most successful recent approaches to capturing the fundamental features of the structure and dynamics of complex systems has been the investigation of the networks associated with the above units (nodes) together with their relations (edges). Most complex systems have an inherently hierarchical organization and, correspondingly, the networks behind them also exhibit hierarchical features. Indeed, several papers have been devoted to describing this essential aspect of networks, however, without resulting in a widely accepted, converging concept concerning the quantitative characterization of the level of their hierarchy. Here we develop an approach and propose a quantity (measure) which is simple enough to be widely applicable, reveals a number of universal features of the organization of real-world networks and, as we demonstrate, is capable of capturing the essential features of the structure and the degree of hierarchy in a complex network. The measure we introduce is based on a generalization of the m-reach centrality, which we first extend to directed/partially directed graphs. Then, we define the global reaching centrality (GRC), which is the difference between the maximum and the average value of the generalized reach centralities over the network. We investigate the behavior of the GRC considering both a synthetic model with an adjustable level of hierarchy and real networks. Results for real networks show that our hierarchy measure is related to the controllability of the given system. We also propose a visualization procedure for large complex networks that can be used to obtain an overall qualitative picture about the nature of their hierarchical structure. PMID:22470477

Fermion mass hierarchies in theories of technicolor

International Nuclear Information System (INIS)

Peskin, M.E.

1981-01-01

Models in which light fermion masses result from dynamical symmetry breaking often produce these masses in a hierarchial pattern. The author exhibits two scenarios for obtaining such hierarchies and illustrates each with a simple model of mass generation. In the first scenario, the light fermion masses are separated by powers of a weak coupling constant; in the second scenario, they are separated by a ratio of large mass scales

The analytic hierarchy process as a support for decision making

Directory of Open Access Journals (Sweden)

Filipović Milanka

2007-01-01

Full Text Available The first part of this text deals with a convention site selection as one of the most lucrative areas in the tourism industry. The second part gives a further description of a method for decision making - the analytic hierarchy process. The basic characteristics: hierarchy constructions and pair wise comparison on the given level of the hierarchy are allured. The third part offers an example of application. This example is solved using the Super - Decision software, which is developed as a computer support for the analytic hierarchy process. This indicates that the AHP approach is a useful tool to help support a decision of convention site selection. .

Critical constraints on chiral hierarchies

International Nuclear Information System (INIS)

Chivukula, R.S.; Golden, M.; Simmons, E.H.

1993-01-01

Critical dynamics constrains models of dynamical electroweak symmetry breaking in which the scale of high-energy physics is far above 1 TeV. A big hierarchy requires the high-energy theory to have a second-order chiral phase transition, near which the theory is described by a low-energy effective Lagrangian with composite ''Higgs'' scalars. As scalar theories with more than one Φ 4 coupling can have a Coleman-Weinberg instability and a first-order transition, such dynamical EWSB models cannot always support a large hierarchy. If the large-N c Nambu--Jona-Lasinio model is a good approximation to the top-condensate and strong extended technicolor models, they will not produce acceptable EWSB

Gauge theories, duality relations and the tensor hierarchy

NARCIS (Netherlands)

Bergshoeff, Eric A.; Hartong, Jelle; Hohm, Olaf; Huebscher, Mechthild; Ortin, Tomas; Hübscher, Mechthild

We compute the complete 3- and 4-dimensional tensor hierarchies, i.e. sets of p-form fields, with 1 We construct gauge-invariant actions that include all the fields in the tensor hierarchies. We elucidate the relation between the gauge transformations of the p-form fields in the action and those of

The association between combined non-cystic fibrosis bronchiectasis and lung cancer in patients with chronic obstructive lung disease

Directory of Open Access Journals (Sweden)

Kim YW

2015-05-01

Full Text Available Yeon Wook Kim,1 Kwang-Nam Jin,2 Eun Young Heo,3 Sung Soo Park,3 Hee Soon Chung,3 Deog Kyeom Kim31Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea; 2Department of Radiology, Seoul National University College of Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Republic of Korea; 3Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Republic of KoreaBackground: Whereas the epidemiological association between lung cancer and chronic obstructive pulmonary disease (COPD, a chronic inflammatory respiratory disease, is well known, limited studies have examined the association between lung cancer and non-cystic fibrosis bronchiectasis, a representative chronic airway inflammatory disease. This study evaluated the association between bronchiectasis and lung cancer in patients with COPD.Methods: A matched case–control study was conducted in a referral hospital in South Korea. Among COPD patients with moderate to very severe airflow limitation (forced expiratory volume in one second/forced vital capacity <0.7 and forced expiratory volume in one second ≤70% [% predicted] who underwent chest computed tomography (CT between January 1, 2010 and May 30, 2013, patients with lung cancer and controls matched for age, sex, and smoking history were selected. The risk of lung cancer was assessed according to the presence of underlying bronchiectasis confirmed by chest CT.Results: The study enrolled 99 cases and 198 controls. Combined bronchiectasis on chest CT was inversely associated with the risk of lung cancer compared with controls (odds ratio [OR] 0.25, 95% confidence interval [CI] 0.12–0.52, P<0.001. Significant associations were found in

A Bayesian Sampler for Optimization of Protein Domain Hierarchies

Science.gov (United States)

2014-01-01

Abstract The process of identifying and modeling functionally divergent subgroups for a specific protein domain class and arranging these subgroups hierarchically has, thus far, largely been done via manual curation. How to accomplish this automatically and optimally is an unsolved statistical and algorithmic problem that is addressed here via Markov chain Monte Carlo sampling. Taking as input a (typically very large) multiple-sequence alignment, the sampler creates and optimizes a hierarchy by adding and deleting leaf nodes, by moving nodes and subtrees up and down the hierarchy, by inserting or deleting internal nodes, and by redefining the sequences and conserved patterns associated with each node. All such operations are based on a probability distribution that models the conserved and divergent patterns defining each subgroup. When we view these patterns as sequence determinants of protein function, each node or subtree in such a hierarchy corresponds to a subgroup of sequences with similar biological properties. The sampler can be applied either de novo or to an existing hierarchy. When applied to 60 protein domains from multiple starting points in this way, it converged on similar solutions with nearly identical log-likelihood ratio scores, suggesting that it typically finds the optimal peak in the posterior probability distribution. Similarities and differences between independently generated, nearly optimal hierarchies for a given domain help distinguish robust from statistically uncertain features. Thus, a future application of the sampler is to provide confidence measures for various features of a domain hierarchy. PMID:24494927

The Development of Hierarchy of Effects Model in Advertising

Directory of Open Access Journals (Sweden)

Bambang Sukma Wijaya

2012-04-01

Full Text Available This paper aims to review the hierarchy of effects models in adverti-sing, especially the well-known model, AIDA (Attention, Interest, De-sire, and Action. Since its introduction by Lewis (1900 and generally attributed in the marketing and advertising literature by Strong (1925, the concept of AIDA’s hierarchy of effects model has been used by many researchers, both academicians and practitioners. The model is used to measure the effect of an advertisement. However, the deve-lopment of information technology has radically changed the way of how people communicate and socialize; as well as a paradigm shift from product-oriented marketing to consumer-oriented marketing or people-oriented marketing. Therefore, the variables in the hierarchy of effects model needs to be updated in respond to the latest develop-ments in the notice of public power as consumer audience. Based on deep literature review and reflective method, this paper introduces a new developed concept of hierarchy of effects model that was adop-ted from AIDA’s hierarchy of effects model, namely: AISDALSLove (At-tention, Interest, Search, Desire, Action, Like/dislike, Share, and Love/hate.

New Positive and Negative Hierarchies of Integrable Differential-Difference Equations and Conservation Laws

International Nuclear Information System (INIS)

Li Xinyue; Zhao Qiulan

2009-01-01

Two hierarchies of nonlinear integrable positive and negative lattice equations are derived from a discrete spectral problem. The two lattice hierarchies are proved to have discrete zero curvature representations associated with a discrete spectral problem, which also shows that the positive and negative hierarchies correspond to positive and negative power expansions of Lax operators with respect to the spectral parameter, respectively. Moreover, the integrable lattice models in the positive hierarchy are of polynomial type, and the integrable lattice models in the negative hierarchy are of rational type. Further, we construct infinite conservation laws about the positive hierarchy.

A Global Mitigation Hierarchy for Nature Conservation

Science.gov (United States)

Bull, Joseph W; Addison, Prue F E; Burgass, Michael J; Gianuca, Dimas; Gorham, Taylor M; Jacob, Céline; Watson, James E M; Wilcox, Chris; Milner-Gulland, E J

2018-01-01

Abstract Efforts to conserve biodiversity comprise a patchwork of international goals, national-level plans, and local interventions that, overall, are failing. We discuss the potential utility of applying the mitigation hierarchy, widely used during economic development activities, to all negative human impacts on biodiversity. Evaluating all biodiversity losses and gains through the mitigation hierarchy could help prioritize consideration of conservation goals and drive the empirical evaluation of conservation investments through the explicit consideration of counterfactual trends and ecosystem dynamics across scales. We explore the challenges in using this framework to achieve global conservation goals, including operationalization and monitoring and compliance, and we discuss solutions and research priorities. The mitigation hierarchy's conceptual power and ability to clarify thinking could provide the step change needed to integrate the multiple elements of conservation goals and interventions in order to achieve successful biodiversity outcomes. PMID:29731513

Flexible scheme to truncate the hierarchy of pure states.

Science.gov (United States)

Zhang, P-P; Bentley, C D B; Eisfeld, A

2018-04-07

The hierarchy of pure states (HOPS) is a wavefunction-based method that can be used for numerically modeling open quantum systems. Formally, HOPS recovers the exact system dynamics for an infinite depth of the hierarchy. However, truncation of the hierarchy is required to numerically implement HOPS. We want to choose a "good" truncation method, where by "good" we mean that it is numerically feasible to check convergence of the results. For the truncation approximation used in previous applications of HOPS, convergence checks are numerically challenging. In this work, we demonstrate the application of the "n-particle approximation" to HOPS. We also introduce a new approximation, which we call the "n-mode approximation." We then explore the convergence of these truncation approximations with respect to the number of equations required in the hierarchy in two exemplary problems: absorption and energy transfer of molecular aggregates.

Flexible scheme to truncate the hierarchy of pure states

Science.gov (United States)

Zhang, P.-P.; Bentley, C. D. B.; Eisfeld, A.

2018-04-01

The hierarchy of pure states (HOPS) is a wavefunction-based method that can be used for numerically modeling open quantum systems. Formally, HOPS recovers the exact system dynamics for an infinite depth of the hierarchy. However, truncation of the hierarchy is required to numerically implement HOPS. We want to choose a "good" truncation method, where by "good" we mean that it is numerically feasible to check convergence of the results. For the truncation approximation used in previous applications of HOPS, convergence checks are numerically challenging. In this work, we demonstrate the application of the "n-particle approximation" to HOPS. We also introduce a new approximation, which we call the "n-mode approximation." We then explore the convergence of these truncation approximations with respect to the number of equations required in the hierarchy in two exemplary problems: absorption and energy transfer of molecular aggregates.

Symmetries of integrable hierarchies and matrix model constraints

International Nuclear Information System (INIS)

Vos, K. de

1992-01-01

The orbit construction associates a soliton hierarchy to every level-one vertex realization of a simply laced affine Kac-Moody algebra g. We show that the τ-function of such a hierarchy has the (truncated) Virasoro algebra as an algebra of infinitesimal symmetry transformations. To prove this we use an appropriate bilinear form of these hierarchies together with the coset construction of conformal field theory. For A 1 (1) the orbit construction gives either the Toda or the KdV hierarchy. These both occur in the one-matrix model of two-dimensional quantum gravity, before and after the double scaling limit respectively. The truncated Virasoro symmetry algebra is exactly the algebra of constraints of the one-matrix model. The partition function of the one-matrix model is therefore an invariant τ-function. We also consider the case of A 1 (1) with l>1. Surprisingly, the symmetry algebra in that case is not simply a truncated Casimir algebra. It appears that again only the Virasoro symmetry survives. We speculate on the relation with multi-matrix models. (orig.)

Effects of neutrino oscillation on supernova neutrino. Inverted mass hierarchy

International Nuclear Information System (INIS)

Takahashi, Keitaro; Sato, Katsuhiko

2003-01-01

We study the effects of neutrino oscillation on supernova neutrinos in the case of the inverted mass hierarchy (m 3 1 2 ) as well as the normal mass hierarchy (m 1 2 3 ). Numerical analysis using realistic supernova and presupernova models allows us to investigate quantitatively the possibility to probe neutrino oscillation parameters. We show that information about the mass hierarchy can be obtained if θ 13 is rather large (sin 2 2θ 13 > 10 -3 ) and that θ 13 can be probed effectively by SuperKamiokande if the neutrino mass hierarchy is inverted. Errors due to the uncertainty in the original neutrino spectra and the Earth effect are also discussed. (author)

Procjena citomorfologije, HPV statusa i HPV 16 genotipa u predikciji ishoda bolesti kod pacijentica s citološkim nalazom ASCUS i LSIL

OpenAIRE

Vrdoljak-Mozetič, Danijela; Štemberger-Papić, Snježana; Verša Ostojić, Damjana; Rubeša-Mihaljević, Roberta; Dinter, Morana; Brnčić-Fischer, Alemka; Krašević, Maja

2016-01-01

Cilj: Istražiti međusobnu povezanost i prognostički značaj HPV statusa (humani papiloma-virus), HPV 16 genotipa i citomorfologije kod pacijentica s citološkim nalazom abnormalnih stanica pločastog epitela vrata maternice graničnog i blagog stupnja. Materijali i metode: U studiju su uključene pacijentice s inicijalnim citološkim nalazom vrata maternice atipičnih skvamoznih stanica neodređenog značenja (ASCUS, N = 160) i skvamozne intraepitelne lezije niskog stupnja (LSIL, N = 155). Analizirane...

Seeking structure in social organization: compensatory control and the psychological advantages of hierarchy.

Science.gov (United States)

Friesen, Justin P; Kay, Aaron C; Eibach, Richard P; Galinsky, Adam D

2014-04-01

Hierarchies are a ubiquitous form of human social organization. We hypothesized that 1 reason for the prevalence of hierarchies is that they offer structure and therefore satisfy the core motivational needs for order and control relative to less structured forms of social organization. This hypothesis is rooted in compensatory control theory, which posits that (a) individuals have a basic need to perceive the world as orderly and structured, and (b) personal and external sources of control are capable of satisfying this need because both serve the comforting belief that the world operates in an orderly fashion. Our first 2 studies confirmed that hierarchies were perceived as more structured and orderly relative to egalitarian arrangements (Study 1) and that working in a hierarchical workplace promotes a feeling of self-efficacy (Study 2). We threatened participants' sense of personal control and measured perceptions of and preferences for hierarchy in 5 subsequent experiments. Participants who lacked control perceived more hierarchy occurring in ambiguous social situations (Study 3) and preferred hierarchy more strongly in workplace contexts (Studies 4-5). We also provide evidence that hierarchies are indeed appealing because of their structure: Preference for hierarchy was higher among individuals high in Personal Need for Structure and a control threat increased preference for hierarchy even among participants low in Personal Need for Structure (Study 5). Framing a hierarchy as unstructured reversed the effect of control threat on hierarchy (Study 6). Finally, hierarchy-enhancing jobs were more appealing after control threat, even when they were low in power and status (Study 7). (PsycINFO Database Record (c) 2014 APA, all rights reserved).

Towards Interactive Construction of Topical Hierarchy: A Recursive Tensor Decomposition Approach.

Science.gov (United States)

Wang, Chi; Liu, Xueqing; Song, Yanglei; Han, Jiawei

2015-08-01

Automatic construction of user-desired topical hierarchies over large volumes of text data is a highly desirable but challenging task. This study proposes to give users freedom to construct topical hierarchies via interactive operations such as expanding a branch and merging several branches. Existing hierarchical topic modeling techniques are inadequate for this purpose because (1) they cannot consistently preserve the topics when the hierarchy structure is modified; and (2) the slow inference prevents swift response to user requests. In this study, we propose a novel method, called STROD, that allows efficient and consistent modification of topic hierarchies, based on a recursive generative model and a scalable tensor decomposition inference algorithm with theoretical performance guarantee. Empirical evaluation shows that STROD reduces the runtime of construction by several orders of magnitude, while generating consistent and quality hierarchies.

Materials with structural hierarchy

Science.gov (United States)

Lakes, Roderic

1993-01-01

The role of structural hierarchy in determining bulk material properties is examined. Dense hierarchical materials are discussed, including composites and polycrystals, polymers, and biological materials. Hierarchical cellular materials are considered, including cellular solids and the prediction of strength and stiffness in hierarchical cellular materials.

A hierarchy of time-scales and the brain.

Science.gov (United States)

Kiebel, Stefan J; Daunizeau, Jean; Friston, Karl J

2008-11-01

In this paper, we suggest that cortical anatomy recapitulates the temporal hierarchy that is inherent in the dynamics of environmental states. Many aspects of brain function can be understood in terms of a hierarchy of temporal scales at which representations of the environment evolve. The lowest level of this hierarchy corresponds to fast fluctuations associated with sensory processing, whereas the highest levels encode slow contextual changes in the environment, under which faster representations unfold. First, we describe a mathematical model that exploits the temporal structure of fast sensory input to track the slower trajectories of their underlying causes. This model of sensory encoding or perceptual inference establishes a proof of concept that slowly changing neuronal states can encode the paths or trajectories of faster sensory states. We then review empirical evidence that suggests that a temporal hierarchy is recapitulated in the macroscopic organization of the cortex. This anatomic-temporal hierarchy provides a comprehensive framework for understanding cortical function: the specific time-scale that engages a cortical area can be inferred by its location along a rostro-caudal gradient, which reflects the anatomical distance from primary sensory areas. This is most evident in the prefrontal cortex, where complex functions can be explained as operations on representations of the environment that change slowly. The framework provides predictions about, and principled constraints on, cortical structure-function relationships, which can be tested by manipulating the time-scales of sensory input.

A hierarchy of time-scales and the brain.

Directory of Open Access Journals (Sweden)

Stefan J Kiebel

2008-11-01

Full Text Available In this paper, we suggest that cortical anatomy recapitulates the temporal hierarchy that is inherent in the dynamics of environmental states. Many aspects of brain function can be understood in terms of a hierarchy of temporal scales at which representations of the environment evolve. The lowest level of this hierarchy corresponds to fast fluctuations associated with sensory processing, whereas the highest levels encode slow contextual changes in the environment, under which faster representations unfold. First, we describe a mathematical model that exploits the temporal structure of fast sensory input to track the slower trajectories of their underlying causes. This model of sensory encoding or perceptual inference establishes a proof of concept that slowly changing neuronal states can encode the paths or trajectories of faster sensory states. We then review empirical evidence that suggests that a temporal hierarchy is recapitulated in the macroscopic organization of the cortex. This anatomic-temporal hierarchy provides a comprehensive framework for understanding cortical function: the specific time-scale that engages a cortical area can be inferred by its location along a rostro-caudal gradient, which reflects the anatomical distance from primary sensory areas. This is most evident in the prefrontal cortex, where complex functions can be explained as operations on representations of the environment that change slowly. The framework provides predictions about, and principled constraints on, cortical structure-function relationships, which can be tested by manipulating the time-scales of sensory input.

Stability of mass hierarchy in models with a sliding singlet

International Nuclear Information System (INIS)

Smirnov, A.Yu.; Tainov, E.A.

1986-01-01

In the broad class of models with a heavy sliding singlet and softly broken supersymmetry (e.g. by the effects of N=1 supergravity) it is shown that the doublet-triplet hierarchy obtained at the tree level is not destroyed by quantum correction at any loop order. As an example the simplest SU(5) model with a stable doublet-triplet hierarchy is proposed. The necessary and sufficient conditions of the hierarchy stability are discussed. (orig.)

The Theory of Ratio Scale Estimation: Saaty's Analytic Hierarchy Process

OpenAIRE

Patrick T. Harker; Luis G. Vargas

1987-01-01

The Analytic Hierarchy Process developed by Saaty (Saaty, T. L. 1980. The Analytic Hierarchy Process. McGraw-Hill, New York.) has proven to be an extremely useful method for decision making and planning. However, some researchers in these areas have raised concerns over the theoretical basis underlying this process. This paper addresses currently debated issues concerning the theoretical foundations of the Analytic Hierarchy Process. We also illustrate through proof and through examples the v...

Towards Lax Formulation of Integrable Hierarchies of Topological Type

NARCIS (Netherlands)

Carlet, G.; van de Leur, J.; Posthuma, H.; Shadrin, S.

2014-01-01

To each partition function of cohomological field theory one can associate an Hamiltonian integrable hierarchy of topological type. The Givental group acts on such partition functions and consequently on the associated integrable hierarchies. We consider the Hirota and Lax formulations of the

Towards Lax Formulation of Integrable Hierarchies of Topological Type

NARCIS (Netherlands)

van de Leur, Johannes; Carlet, Guido; Shadrin, Sergey; Posthuma, Hessel

2014-01-01

To each partition function of cohomological field theory one can associate an Hamiltonian integrable hierarchy of topological type. The Givental group acts on such partition functions and consequently on the associated integrable hierarchies. We consider theHirota and Lax formulations of the

Optimal City Hierarchy: A Dynamic Programming Approach to Central Place Theory

OpenAIRE

Wen-Tai Hsu; Thomas J. Holmes

2009-01-01

It is an empirically plausible description of cities and is route to explain empirical regularities in city size distribution and industrial locations. This paper formalizes central place hierarchy by providing a rationale for it via a social planner's problem. The optimal city hierarchy is then compared with the equilibrium city hierarchy in Hsu (2008).

The fate of calcium carbonate nanoparticles administered by oral route: absorption and their interaction with biological matrices

Directory of Open Access Journals (Sweden)

Lee JA

2015-03-01

Full Text Available Jeong-A Lee,1,* Mi-Kyung Kim,1,* Hyoung-Mi Kim,2,* Jong Kwon Lee,3 Jayoung Jeong,4 Young-Rok Kim,5 Jae-Min Oh,2 Soo-Jin Choi1 1Department of Food Science and Technology, Seoul Women’s University, Seoul, Republic of Korea; 2Department of Chemistry and Medical Chemistry, College of Science and Technology, Yonsei University, Wonju, Republic of Korea; 3Hazard Substances Analysis Division, Gwangju Regional Food and Drug Administration, Ministry of Food and Drug Safety, Gwangju, Republic of Korea; 4Toxicological Research Division, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Chungcheongbuk-do, Republic of Korea; 5Department of Food Science and Biotechnology, Kyung Hee University, Yongin, Republic of Korea *These authors contributed equally to this work Background: Orally administered particles rapidly interact with biological fluids containing proteins, enzymes, electrolytes, and other biomolecules to eventually form particles covered by a corona, and this corona potentially affects particle uptake, fate, absorption, distribution, and elimination in vivo. This study explored relationships between the biological interactions of calcium carbonate particles and their biokinetics.Methods: We examined the effects of food grade calcium carbonates of different particle size (nano [N-Cal] and bulk [B-Cal]: specific surface areas of 15.8 and 0.83 m2/g, respectively on biological interactions in in vitro simulated physiological fluids, ex vivo biofluids, and in vivo in gastrointestinal fluid. Moreover, absorption and tissue distribution of calcium carbonates were evaluated following a single dose oral administration to rats.Results: N-Cal interacted more with biomatrices than bulk materials in vitro and ex vivo, as evidenced by high fluorescence quenching ratios, but it did not interact more actively with biomatrices in vivo. Analysis of coronas revealed that immunoglobulin, apolipoprotein, thrombin, and fibrinogen

Soliton solutions by Darboux transformation and some reductions for a new Hamiltonian lattice hierarchy

International Nuclear Information System (INIS)

Tian Shoufu; Zhang Hongqing

2010-01-01

In this paper, we start from the discrete spectral problem and construct a lattice hierarchy by properly choosing an auxiliary spectral problem V-tilde n (m) , which can reduce to the Volterra hierarchy, the Ablowitz-Ladik hierarchy, positive and negative lattice hierarchies and a new hierarchy. The new hierarchy is integrable in involutory Lax's sense and possesses multi-Hamiltonian structure. In addition, the Darboux transformation of the lattice hierarchy is obtained when the freely adjustable function εn (1) =0 and m=1. Then some soliton solutions are obtained by using Darboux transformation. This method is also suitable for other more general spectral problems in mathematics and physics.

On an extended second Painlevé hierarchy

Science.gov (United States)

Gordoa, P. R.; Pickering, A.

2017-10-01

We present a new extension of the second Painlevé hierarchy and study its properties. In addition to Lax pairs, Bäcklund transformations, auto-Bäcklund transformations and basic special integrals, we also consider a new phenomenon whereby we obtain relations between systems of different orders but of the same form. The extension made here of the second Painlevé hierarchy is based on the use of non-isospectral scattering problems and so is quite general. We thus expect to be able to obtain similar extensions of other Painlevé hierarchies, including not only for continuous examples but also for discrete and differential-delay examples. We believe that our work is also of relevance for Painlevé classification, since it gives information about classes of equation that may be of interest and in addition provides a key to the possible identification of equations isolated in such a process.

Darboux transformation and soliton solutions for the Boiti-Pempinelli-Tu (BPT) hierarchy

International Nuclear Information System (INIS)

Wang Jiong

2005-01-01

Starting from a spectral problem, we derive the well-known Boiti-Pempinelli-Tu (BPT) hierarchy. An explicit and universal Darboux transformation for the whole hierarchy is constructed. The soliton solutions for the BPT hierarchy are obtained by applying the Darboux transformation

Reactions to Crime as a Hierarchy Regulating Strategy:

DEFF Research Database (Denmark)

Green, Eva G. T.; Thomsen, Lotte; Sidanius, Jim

2009-01-01

Across two studies, we demonstrated that support for group-based hierarchies differentially affects evaluation of ingroup and outgroup criminal offenders and that this effect generalizes to overall evaluations of their respective groups. Drawing on social dominance theory, our results show that d...... of ethnicity or nationality, not education level and employment status, were the important cues for hierarchy-regulating judgments of criminal offenders...

Supersymmetric KP hierarchy in N=1 superspace and its N=2 reductions

International Nuclear Information System (INIS)

Lechtenfeld, O.; Sorin, A.

2000-01-01

A wide class of N=2 reductions of the supersymmetric KP hierarchy in N=1 superspace is described. This class includes a new N=2 supersymmetric generalization of the Toda chain hierarchy. The Lax pair representations of the bosonic and fermionic flows, local and non-local Hamiltonians, finite and infinite discrete symmetries, first two Hamiltonian structures and the recursion operator of this hierarchy are constructed. Its secondary reduction to new N=2 supersymmetric modified KdV hierarchy is discussed

Supersymmetric KP hierarchy in N=1 superspace and its N=2 reductions

International Nuclear Information System (INIS)

Lechtenfeld, O.; Sorin, A.

1999-01-01

A wide class of N=2 reductions of the supersymmetric KP hierarchy in N=1 superspace is described. This class includes a new N=2 supersymmetric generalization of the Toda chain hierarchy. The Lax pair representations of the bosonic and fermionic flows, local and nonlocal Hamiltonians, finite and infinite discrete symmetries, first two Hamiltonian structures and the recursion operator of this hierarchy are constructed. Its secondary reduction to new N=2 supersymmetric modified KdV hierarchy is discussed

Solving the wrong hierarchy problem

International Nuclear Information System (INIS)

Blinov, Nikita; Hook, Anson

2016-01-01

Many theories require augmenting the Standard Model with additional scalar fields with large order one couplings. We present a new solution to the hierarchy problem for these scalar fields. We explore parity- and Z_2-symmetric theories where the Standard Model Higgs potential has two vacua. The parity or Z_2 copy of the Higgs lives in the minimum far from the origin while our Higgs occupies the minimum near the origin of the potential. This approach results in a theory with multiple light scalar fields but with only a single hierarchy problem, since the bare mass is tied to the Higgs mass by a discrete symmetry. The new scalar does not have a new hierarchy problem associated with it because its expectation value and mass are generated by dimensional transmutation of the scalar quartic coupling. The location of the second Higgs minimum is not a free parameter, but is rather a function of the matter content of the theory. As a result, these theories are extremely predictive. We develop this idea in the context of a solution to the strong CP problem. Lastly, we show this mechanism postdicts the top Yukawa to be within 1σ of the currently measured value and predicts scalar color octets with masses in the range 9-200 TeV

Neutrino mass hierarchy determination via atmospheric neutrinos with future detectors

International Nuclear Information System (INIS)

Gandhi, Raj; Ghoshal, Pomita; Goswami, Srubabati; Mehta, Poonam; Sankar, S Uma; Shalgar, Shashank

2008-01-01

The issue of determining the neutrino mass hierarchy is one of the outstanding questions in neutrino physics. We consider the potential of hierarchy determination using atmospheric neutrinos as the source in three different proposed future detectors: A large Iron Calorimeter detector, a megaton Water Cerenkov detector and a large-mass Liquid Argon detector. If the mixing angle θ 13 is about 10 deg. (close to CHOOZ upper bound), the hierarchy sensitivity is essentially determined by resonant matter effects. To maximize the potential of these effects in atmospheric neutrinos, charge discrimination capability in the detector is desirable. Hence, detectors with this capability have an advantage in hierarchy determination. We compare and contrast the performance of the above three detectors in this respect. We perform a realistic analysis of the above future detectors for atmospheric neutrinos and show that it is possible to achieve a significant hierarchy sensitivity if the detector characteristics are favourable. Note: The abstract has been modified from its original form to incorporate suggestions received during the conference. The poster is being submitted in its original form.

Matrix integral solutions to the discrete KP hierarchy and its Pfaffianized version

International Nuclear Information System (INIS)

Lafortune, Stéphane; Li, Chun-Xia

2016-01-01

Matrix integrals used in random matrix theory for the study of eigenvalues of Hermitian ensembles have been shown to provide τ -functions for several hierarchies of integrable equations. In this article, we extend this relation by showing that such integrals can also provide τ -functions for the discrete KP hierarchy and a coupled version of the same hierarchy obtained through the process of Pfaffianization. To do so, we consider the first equation of the discrete KP hierarchy, the Hirota–Miwa equation. We write the Wronskian determinant solutions to the Hirota–Miwa equation and consider a particular form of matrix integrals, which we show is an example of those Wronskian solutions. The argument is then generalized to the whole hierarchy. A similar strategy is used for the Pfaffianized version of the hierarchy except that in that case, the solutions are written in terms of Pfaffians rather than determinants. (paper)

Nonlinear Super Integrable Couplings of Super Classical-Boussinesq Hierarchy

Directory of Open Access Journals (Sweden)

Xiuzhi Xing

2014-01-01

Full Text Available Nonlinear integrable couplings of super classical-Boussinesq hierarchy based upon an enlarged matrix Lie super algebra were constructed. Then, its super Hamiltonian structures were established by using super trace identity. As its reduction, nonlinear integrable couplings of the classical integrable hierarchy were obtained.

The multi-component WKI hierarchy

International Nuclear Information System (INIS)

Yao Yuqin; Zhang Yufeng

2005-01-01

Firstly a new loop algebra G∼ M with 3M dimensions is constructed, which is devoted to establishing a new isospectral problem. Then the multi-component WKI hierarchy of soliton equations is obtained

SUSY-hierarchy of one-dimensional reflectionless potentials

CERN Document Server

Maydanyuk, Sergei P

2004-01-01

A class of one-dimensional reflectionless potentials, an absolute transparency of which is concerned with their belonging to one SUSY-hierarchy with a constant potential, is studied. An approach for determination of a general form of the reflectionless potential on the basis of construction of such a hierarchy by the recurrent method is proposed. A general form of interdependence between superpotentials with neighboring numbers of this hierarchy, opening a possibility to find new reflectionless potentials, have a simple analytical view and are expressed through finite number of elementary functions (unlike some reflectionless potentials, which are constructed on the basis of soliton solutions or are shape invariant in one or many steps with involving scaling of parameters, and are expressed through series), is obtained. An analysis of absolute transparency existence for the potential which has the inverse power dependence on space coordinate (and here tunneling is possible), i.e. which has the form $V(x) = \\p...

Standard model fermion hierarchies with multiple Higgs doublets

International Nuclear Information System (INIS)

Solaguren-Beascoa Negre, Ana

2016-01-01

The hierarchies between the Standard Model (SM) fermion masses and mixing angles and the origin of neutrino masses are two of the biggest mysteries in particle physics. We extend the SM with new Higgs doublets to solve these issues. The lightest fermion masses and the mixing angles are generated through radiative effects, correctly reproducing the hierarchy pattern. Neutrino masses are generated in the see-saw mechanism.

Behavior-aware cache hierarchy optimization for low-power multi-core embedded systems

Science.gov (United States)

Zhao, Huatao; Luo, Xiao; Zhu, Chen; Watanabe, Takahiro; Zhu, Tianbo

2017-07-01

In modern embedded systems, the increasing number of cores requires efficient cache hierarchies to ensure data throughput, but such cache hierarchies are restricted by their tumid size and interference accesses which leads to both performance degradation and wasted energy. In this paper, we firstly propose a behavior-aware cache hierarchy (BACH) which can optimally allocate the multi-level cache resources to many cores and highly improved the efficiency of cache hierarchy, resulting in low energy consumption. The BACH takes full advantage of the explored application behaviors and runtime cache resource demands as the cache allocation bases, so that we can optimally configure the cache hierarchy to meet the runtime demand. The BACH was implemented on the GEM5 simulator. The experimental results show that energy consumption of a three-level cache hierarchy can be saved from 5.29% up to 27.94% compared with other key approaches while the performance of the multi-core system even has a slight improvement counting in hardware overhead.

Inverted radiative hierarchy of quark masses

International Nuclear Information System (INIS)

Berezhiani, Z.G.; Rattazzi, R.

1992-01-01

Inverted radiative hierarchy of quark masses is investigated. The authors suggest that the mass hierarchy is first generated in a sector of heavy isosinglet fermions due to radiative effects and then projected in the inverted way to the usual quarks by means of a universal seesaw. The simple left-right symmetric gauge model is presented with the P- and CP-parities and the exact isotopical symmetry which are softly (or spontaneously) broken in the Higgs potential. This approach naturally explains the observed pattern of quark masses and mixing, providing the quantitatively correct formula for the Cabibbo angle. Top quark is predicted to be in the 90-150 GeV range

Non-Hamiltonian generalizations of the dispersionless 2DTL hierarchy

International Nuclear Information System (INIS)

Bogdanov, L V

2010-01-01

We consider two-component integrable generalizations of the dispersionless two-dimensional Toda lattice (2DTL) hierarchy connected with non-Hamiltonian vector fields, similar to the Manakov-Santini hierarchy generalizing the dKP hierarchy. They form a one-parametric family connected by hodograph-type transformations. Generating equations and Lax-Sato equations are introduced, and a dressing scheme based on the vector nonlinear Riemann problem is formulated. The simplest two-component generalization of the dispersionless 2DTL equation is derived, and its differential reduction analogous to the Dunajski interpolating system is presented. A symmetric two-component generalization of the dispersionless elliptic 2DTL equation is also constructed.

An Operational Investigation of the CPS Hierarchy

DEFF Research Database (Denmark)

Danvy, Olivier; Yang, Zhe

1999-01-01

We explore the hierarchy of control induced by successive transformations into continuation-passing style (CPS) in the presence of “control delimiters ” and “composable continuations ”. Specifically, we investigate the structural operational semantics associated with the CPS hierarchy. To this end......, we characterize an operational notion of continuation semantics. We relate it to the traditional CPS transformation and we use it to account for the control operator shift and the control delimiter reset operationally. We then transcribe the resulting continuation semantics in ML, thus obtaining...

An Operational Investigation of the CPS Hierarchy

DEFF Research Database (Denmark)

Danvy, Olivier; Yang, Zhe

1998-01-01

We explore the hierarchy of control induced by successive transformations into continuation-passing style (CPS) in the presence of “control delimiters ” and “composable continuations ”. Specifically, we investigate the structural operational semantics associated with the CPS hierarchy. To this end......, we characterize an operational notion of continuation semantics. We relate it to the traditional CPS transformation and we use it to account for the control operator shift and the control delimiter reset operationally. We then transcribe the resulting continuation semantics in ML, thus obtaining...

A Second Look at Maslow's Hierarchy of Basic Needs.

Science.gov (United States)

White, Charles M.

Implications of Maslow's Need Hierarchy are considered in this paper, along with possible qualifications to the suggested structure and potential effects of superimposing relative deprivation theory onto the hierarchy as an approach to adult education. The interfacing of needs and alternative structurings is discussed in terms of two theories: (1)…

Psychophysical "blinding" methods reveal a functional hierarchy of unconscious visual processing.

Science.gov (United States)

Breitmeyer, Bruno G

2015-09-01

Numerous non-invasive experimental "blinding" methods exist for suppressing the phenomenal awareness of visual stimuli. Not all of these suppressive methods occur at, and thus index, the same level of unconscious visual processing. This suggests that a functional hierarchy of unconscious visual processing can in principle be established. The empirical results of extant studies that have used a number of different methods and additional reasonable theoretical considerations suggest the following tentative hierarchy. At the highest levels in this hierarchy is unconscious processing indexed by object-substitution masking. The functional levels indexed by crowding, the attentional blink (and other attentional blinding methods), backward pattern masking, metacontrast masking, continuous flash suppression, sandwich masking, and single-flash interocular suppression, fall at progressively lower levels, while unconscious processing at the lowest levels is indexed by eye-based binocular-rivalry suppression. Although unconscious processing levels indexed by additional blinding methods is yet to be determined, a tentative placement at lower levels in the hierarchy is also given for unconscious processing indexed by Troxler fading and adaptation-induced blindness, and at higher levels in the hierarchy indexed by attentional blinding effects in addition to the level indexed by the attentional blink. The full mapping of levels in the functional hierarchy onto cortical activation sites and levels is yet to be determined. The existence of such a hierarchy bears importantly on the search for, and the distinctions between, neural correlates of conscious and unconscious vision. Copyright © 2015 Elsevier Inc. All rights reserved.

Global network structure of dominance hierarchy of ant workers.

Science.gov (United States)

Shimoji, Hiroyuki; Abe, Masato S; Tsuji, Kazuki; Masuda, Naoki

2014-10-06

Dominance hierarchy among animals is widespread in various species and believed to serve to regulate resource allocation within an animal group. Unlike small groups, however, detection and quantification of linear hierarchy in large groups of animals are a difficult task. Here, we analyse aggression-based dominance hierarchies formed by worker ants in Diacamma sp. as large directed networks. We show that the observed dominance networks are perfect or approximate directed acyclic graphs, which are consistent with perfect linear hierarchy. The observed networks are also sparse and random but significantly different from networks generated through thinning of the perfect linear tournament (i.e. all individuals are linearly ranked and dominance relationship exists between every pair of individuals). These results pertain to global structure of the networks, which contrasts with the previous studies inspecting frequencies of different types of triads. In addition, the distribution of the out-degree (i.e. number of workers that the focal worker attacks), not in-degree (i.e. number of workers that attack the focal worker), of each observed network is right-skewed. Those having excessively large out-degrees are located near the top, but not the top, of the hierarchy. We also discuss evolutionary implications of the discovered properties of dominance networks. © 2014 The Author(s) Published by the Royal Society. All rights reserved.

A Discrete Spectral Problem and Related Hierarchy of Discrete Hamiltonian Lattice Equations

International Nuclear Information System (INIS)

Xu Xixiang; Cao Weili

2007-01-01

Staring from a discrete matrix spectral problem, a hierarchy of lattice soliton equations is presented though discrete zero curvature representation. The resulting lattice soliton equations possess non-local Lax pairs. The Hamiltonian structures are established for the resulting hierarchy by the discrete trace identity. Liouville integrability of resulting hierarchy is demonstrated.

A Computational Glimpse at the Leibniz and Frege Hierarchies

Czech Academy of Sciences Publication Activity Database

Moraschini, Tommaso

2018-01-01

Roč. 169, č. 1 (2018), s. 1-20 ISSN 0168-0072 R&D Projects: GA ČR GA13-14654S Institutional support: RVO:67985807 Keywords : abstract algebraic logic * Leibniz hierarchy * Frege hierarchy Leibniz congruence * decidability * Diophantine equations * relation algebras Subject RIV: BA - General Mathematics Impact factor: 0.647, year: 2016

Attention modulations on the perception of social hierarchy at distinct temporal stages: an electrophysiological investigation.

Science.gov (United States)

Feng, Chunliang; Tian, Tengxiang; Feng, Xue; Luo, Yue-Jia

2015-04-01

Recent behavioral and neuroscientific studies have revealed the preferential processing of superior-hierarchy cues. However, it remains poorly understood whether top-down controlled mechanisms modulate temporal dynamics of neurocognitive substrates underlying the preferential processing of these biologically and socially relevant cues. This was investigated in the current study by recording event-related potentials from participants who were presented with superior or inferior social hierarchy. Participants performed a hierarchy-judgment task that required attention to hierarchy cues or a gender-judgment task that withdrew their attention from these cues. Superior-hierarchy cues evoked stronger neural responses than inferior-hierarchy cues at both early (N170/N200) and late (late positive potential, LPP) temporal stages. Notably, the modulations of top-down attention were identified on the LPP component, such that superior-hierarchy cues evoked larger LPP amplitudes than inferior-hierarchy cues only in the attended condition; whereas the modulations of the N170/N200 component by hierarchy cues were evident in both attended and unattended conditions. These findings suggest that the preferential perception of superior-hierarchy cues involves both relatively automatic attentional bias at the early temporal stage as well as flexible and voluntary cognitive evaluation at the late temporal stage. Finally, these hierarchy-related effects were absent when participants were shown the same stimuli which, however, were not associated with social-hierarchy information in a non-hierarchy task (Experiment 2), suggesting that effects of social hierarchy at early and late temporal stages could not be accounted for by differences in physical attributes between these social cues. Copyright © 2015 Elsevier Ltd. All rights reserved.

New Integrable Couplings of Generalized Kaup-Newell Hierarchy and Its Hamiltonian Structures

International Nuclear Information System (INIS)

Xia Tiecheng; Zhang Gailian; Fan Engui

2011-01-01

A new isospectral problem is firstly presented, then we derive integrable system of soliton hierarchy. Also we obtain new integrable couplings of the generalized Kaup-Newell soliton equations hierarchy and its Hamiltonian structures by using Tu scheme and the quadratic-form identity. The method can be generalized to other soliton hierarchy. (general)

Block (or Hamiltonian) Lie Symmetry of Dispersionless D-Type Drinfeld–Sokolov Hierarchy

International Nuclear Information System (INIS)

Li Chuan-Zhong; He Jing-Song; Su Yu-Cai

2014-01-01

In this paper, the dispersionless D-type Drinfeld–Sokolov hierarchy, i.e. a reduction of the dispersionless two-component BKP hierarchy, is studied. The additional symmetry flows of this hierarchy are presented. These flows form an infinite-dimensional Lie algebra of Block type as well as a Lie algebra of Hamiltonian type

Enhanced bioavailability of sirolimus via preparation of solid dispersion nanoparticles using a supercritical antisolvent process

Directory of Open Access Journals (Sweden)

Kim MS

2011-11-01

Full Text Available Min-Soo Kim1, Jeong-Soo Kim1, Hee Jun Park1, Won Kyung Cho1,3, Kwang-Ho Cha1,3, Sung-Joo Hwang2,31College of Pharmacy, Chungnam National University, Daejeon, Republic of Korea, 2College of Pharmacy, 3Yonsei Institute of Pharmaceutical Sciences, Yonsei University, Incheon, Republic of KoreaBackground: The aim of this study was to improve the physicochemical properties and bioavailability of poorly water-soluble sirolimus via preparation of a solid dispersion of nanoparticles using a supercritical antisolvent (SAS process.Methods: First, excipients for enhancing the stability and solubility of sirolimus were screened. Second, using the SAS process, solid dispersions of sirolimus-polyvinylpyrrolidone (PVP K30 nanoparticles were prepared with or without surfactants such as sodium lauryl sulfate (SLS, tocopheryl propylene glycol succinate, Sucroester 15, Gelucire 50/13, and Myrj 52. A mean particle size of approximately 250 nm was obtained for PVP K30-sirolimus nanoparticles. Solid state characterization, kinetic solubility, powder dissolution, stability, and pharmacokinetics were analyzed in rats.Results: X-ray diffraction, differential scanning calorimetry, and high-pressure liquid chromatography indicated that sirolimus existed in an anhydrous amorphous form within a solid dispersion of nanoparticles and that no degradation occurred after SAS processing. The improved supersaturation and dissolution of sirolimus as a solid dispersion of nanoparticles appeared to be well correlated with enhanced bioavailability of oral sirolimus in rats. With oral administration of a solid dispersion of PVP K30-SLS-sirolimus nanoparticles, the peak concentration and AUC0→12h of sirolimus were increased by approximately 18.3-fold and 15.2-fold, respectively.Conclusion: The results of this study suggest that preparation of PVP K30-sirolimus-surfactant nanoparticles using the SAS process may be a promising approach for improving the bioavailability of sirolimus

Strong Bayesian evidence for the normal neutrino hierarchy

Energy Technology Data Exchange (ETDEWEB)

Simpson, Fergus; Jimenez, Raul; Verde, Licia [ICCUB, University of Barcelona (UB-IEEC), Marti i Franques 1, Barcelona, 08028 (Spain); Pena-Garay, Carlos, E-mail: fergus2@gmail.com, E-mail: raul.jimenez@icc.ub.edu, E-mail: penagaray@gmail.com, E-mail: liciaverde@icc.ub.edu [I2SysBio, CSIC-UVEG, P.O. 22085, Valencia, 46071 (Spain)

2017-06-01

The configuration of the three neutrino masses can take two forms, known as the normal and inverted hierarchies. We compute the Bayesian evidence associated with these two hierarchies. Previous studies found a mild preference for the normal hierarchy, and this was driven by the asymmetric manner in which cosmological data has confined the available parameter space. Here we identify the presence of a second asymmetry, which is imposed by data from neutrino oscillations. By combining constraints on the squared-mass splittings [1] with the limit on the sum of neutrino masses of Σ m {sub ν} < 0.13 eV [2], and using a minimally informative prior on the masses, we infer odds of 42:1 in favour of the normal hierarchy, which is classified as 'strong' in the Jeffreys' scale. We explore how these odds may evolve in light of higher precision cosmological data, and discuss the implications of this finding with regards to the nature of neutrinos. Finally the individual masses are inferred to be m {sub 1}=3.80{sup +26.2}{sub -3.73}meV; m {sub 2}=8.8{sup +18}{sub -1.2}meV; m {sub 3}=50.4{sup +5.8}{sub -1.2}meV (95% credible intervals).

Extended N=2 supersymmetric matrix (1, s)-KdV hierarchies

International Nuclear Information System (INIS)

Krivonos, S.O.; Sorin, A.S.

1997-01-01

We propose the Lax operators for N=2 supersymmetric matrix generalization of the bosonic (1, s)-KdV hierarchies. The simplest examples - the N=2 supersymmetric a=4 KdV and a=5/2 Boussinesq hierarchies - are discussed in detail

The socio-matrix reloaded: from hierarchy to dominance profile in wild lemurs.

Science.gov (United States)

Norscia, Ivan; Palagi, Elisabetta

2015-01-01

Dominance hierarchy influences the life quality of social animals, and its definition should in principle be based on the outcome of agonistic interactions. However, defining and comparing the dominance profile of social groups is difficult due to the different dominance measures used and because no one measure explains it all. We applied different analytical methods to winner-loser sociomatrices to determine the dominance profile of five groups of wild lemurs (species: Lemur catta, Propithecus verreauxi, and Eulemur rufus x collaris) from the Berenty forest (Madagascar). They are an excellent study model because they share the same habitat and an apparently similar dominance profile: linear hierarchy and female dominance. Data were collected over more than 1200 h of observation. Our approach included four steps: (1) by applying the binary dyadic dominance relationship method (I&SI) on either aggressions or supplant sociomatrices we verified whether hierarchy was aggression or submission based; (2) by calculating normalized David's scores and measuring steepness from aggression sociomatrices we evaluated whether hierarchy was shallow or steep; (3) by comparing the ranking orders obtained with methods 1 and 2 we assessed whether hierarchy was consistent or not; and (4) by assessing triangle transitivity and comparing it with the linearity index and the level of group cohesion we determined if hierarchy was more or less cohesive. Our results show that L. catta groups have got a steep, consistent, highly transitive and cohesive hierarchy. P. verreauxi groups are characterized by a moderately steep and consistent hierarchy, with variable levels of triangle transitivity and cohesion. E. rufus x collaris group possesses a shallow and inconsistent hierarchy, with lower (but not lowest) levels of transitivity and cohesion. A multiple analytical approach on winner-loser sociomatrices other than leading to an in-depth description of the dominance profile, allows intergroup

The socio-matrix reloaded: from hierarchy to dominance profile in wild lemurs

Directory of Open Access Journals (Sweden)

Ivan Norscia

2015-01-01

Full Text Available Dominance hierarchy influences the life quality of social animals, and its definition should in principle be based on the outcome of agonistic interactions. However, defining and comparing the dominance profile of social groups is difficult due to the different dominance measures used and because no one measure explains it all. We applied different analytical methods to winner-loser sociomatrices to determine the dominance profile of five groups of wild lemurs (species: Lemur catta, Propithecus verreauxi, and Eulemur rufus x collaris from the Berenty forest (Madagascar. They are an excellent study model because they share the same habitat and an apparently similar dominance profile: linear hierarchy and female dominance. Data were collected over more than 1200 h of observation. Our approach included four steps: (1 by applying the binary dyadic dominance relationship method (I&SI on either aggressions or supplant sociomatrices we verified whether hierarchy was aggression or submission based; (2 by calculating normalized David’s scores and measuring steepness from aggression sociomatrices we evaluated whether hierarchy was shallow or steep; (3 by comparing the ranking orders obtained with methods 1 and 2 we assessed whether hierarchy was consistent or not; and (4 by assessing triangle transitivity and comparing it with the linearity index and the level of group cohesion we determined if hierarchy was more or less cohesive. Our results show that L. catta groups have got a steep, consistent, highly transitive and cohesive hierarchy. P. verreauxi groups are characterized by a moderately steep and consistent hierarchy, with variable levels of triangle transitivity and cohesion. E. rufus x collaris group possesses a shallow and inconsistent hierarchy, with lower (but not lowest levels of transitivity and cohesion. A multiple analytical approach on winner-loser sociomatrices other than leading to an in-depth description of the dominance profile

Materialismo percettivo. Da Democrito a Lenin, da Hobbes a Kim

Directory of Open Access Journals (Sweden)

Michele Gardini

2012-05-01

Full Text Available The paper tries to outline something like a short “critique of pure materialism” in the domain of perception, a sketch showing – through a series of examples, picked out in an apparently heterogeneous fashion from the Western philosophical tradition – how this epistemological model each time, and in everyone of its forms, fails in giving account of the basic features of perceiving.  After giving a survey of authors like Democritus, Hobbes, De Sade, Lenin, the final appendix, devoted to the concept of “supervenience” and its treatment in Davidson and Kim, aims at summarizing the whole problem through the categories of the contemporary philosophy of mind. The conclusion is that a pure materialistic approach is incapable to give reason to some of the fundamental characteristics of perception, that make it one of the basic moods of “being-in-the-world”.

"The Day All of the Different Parts of Me Can Come Along": Intersectionality and U.S. Third World Feminism in the Poetry of Pat Parker and Willyce Kim.

Science.gov (United States)

Van Ausdall, Mimi Iimuro

2015-01-01

This article brings to light the poetry of Pat Parker and Willyce Kim, two key figures within the 1970s and '80s women in print movement. While Parker and Kim have been rightly placed within African-American and Asian-American histories, respectively, and working-class and lesbian-feminist literary histories, their work is most fully understood within the context of U.S. Third World Feminism. Through close readings of poetic form and content in addition to engagement with current debates about intersectionality as a methodology, the article links Kim and Parker's works to central contributions of U.S. Third World Feminism such as intersectionality and power across and within difference that continue to influence feminist theory today.

MOS modeling hierarchy including radiation effects

International Nuclear Information System (INIS)

Alexander, D.R.; Turfler, R.M.

1975-01-01

A hierarchy of modeling procedures has been developed for MOS transistors, circuit blocks, and integrated circuits which include the effects of total dose radiation and photocurrent response. The models were developed for use with the SCEPTRE circuit analysis program, but the techniques are suitable for other modern computer aided analysis programs. The modeling hierarchy permits the designer or analyst to select the level of modeling complexity consistent with circuit size, parametric information, and accuracy requirements. Improvements have been made in the implementation of important second order effects in the transistor MOS model, in the definition of MOS building block models, and in the development of composite terminal models for MOS integrated circuits

A Validation Study of Maslow's Hierarchy of Needs Theory.

Science.gov (United States)

Clay, Rex J.

A study was conducted to expand the body of research that tests the validity of Abraham Maslow's hierarchy of needs theory in a work context where it often serves as a guide for the supervisor's relationships with his subordinates. Data was gathered by questionnaire which tested for a hierarchy of needs among instructors at four community colleges…

An alternative approach to KP hierarchy in matrix models

International Nuclear Information System (INIS)

Bonora, L.; Xiong, C.S.

1992-01-01

We show that there exists an alternative procedure in order to extract differential hierarchies, such as the KdV hierarchy, from one-matrix models, without taking a continuum limit. To prove this we introduce the Toda lattice and reformulate it in operator form. We then consider the reduction to the systems appropriate for a one-matrix model. (orig.)

The super-classical-Boussinesq hierarchy and its super-Hamiltonian structure

International Nuclear Information System (INIS)

Si-Xing, Tao; Tie-Cheng, Xia

2010-01-01

Based on the constructed Lie superalgebra, the super-classical-Boussinesq hierarchy is obtained. Then, its super-Hamiltonian structure is obtained by making use of super-trace identity. Furthermore, the super-classical-Boussinesq hierarchy is also integrable in the sense of Liouville. (general)

VLSI top-down design based on the separation of hierarchies

NARCIS (Netherlands)

Spaanenburg, L.; Broekema, A.; Leenstra, J.; Huys, C.

1986-01-01

Despite the presence of structure, interactions between the three views on VLSI design still lead to lengthy iterations. By separating the hierarchies for the respective views, the interactions are reduced. This separated hierarchy allows top-down design with functional abstractions as exemplified

Do Convolutional Neural Networks Learn Class Hierarchy?

Science.gov (United States)

Bilal, Alsallakh; Jourabloo, Amin; Ye, Mao; Liu, Xiaoming; Ren, Liu

2018-01-01

Convolutional Neural Networks (CNNs) currently achieve state-of-the-art accuracy in image classification. With a growing number of classes, the accuracy usually drops as the possibilities of confusion increase. Interestingly, the class confusion patterns follow a hierarchical structure over the classes. We present visual-analytics methods to reveal and analyze this hierarchy of similar classes in relation with CNN-internal data. We found that this hierarchy not only dictates the confusion patterns between the classes, it furthermore dictates the learning behavior of CNNs. In particular, the early layers in these networks develop feature detectors that can separate high-level groups of classes quite well, even after a few training epochs. In contrast, the latter layers require substantially more epochs to develop specialized feature detectors that can separate individual classes. We demonstrate how these insights are key to significant improvement in accuracy by designing hierarchy-aware CNNs that accelerate model convergence and alleviate overfitting. We further demonstrate how our methods help in identifying various quality issues in the training data.

Effective potentials for supersymmetric three-scale hierarchies

International Nuclear Information System (INIS)

Polchinski, J.

1983-01-01

We consider the effective potential in models in which supersymmetry breaks at a scale μ but the Goldstone fermion couples only to fields of mass M>>μ. We show that all large perturbative logarithms are removed by taking the renormalization point to be O(M). This makes it possible to calculate the effective potential at large X in those inverted-hierarchy models where the Goldstone fermion couples only to superheavy fields. A general formula for the one-loop logarithm in these models is given. We illustrate the results with an SU(n) example in which the direction as well as the magnitude of the gauge symmetry breaking is undetermined at the tree level. For this example a large perturbative hierarchy does not form and the unbroken subgroup is always SU(n-1) x U(1). In an appendix we show that O'Raifeartaigh models with just one undetermined scalar field always have a decoupled Goldstone fermion when the undetermined field is large, but that this need not be true in more general inverted-hierarchy models

A modified Toda spectral problem and its hierarchy of bi-Hamiltonian lattice equations

International Nuclear Information System (INIS)

Ma Wenxiu; Xu Xixiang

2004-01-01

Starting from a modified Toda spectral problem, a hierarchy of generalized Toda lattice equations with two arbitrary constants is constructed through discrete zero curvature equations. It is shown that the hierarchy possesses a bi-Hamiltonian structure and a hereditary recursion operator, which implies that there exist infinitely many common commuting symmetries and infinitely many common commuting conserved functionals. Two cases of the involved constants present two specific integrable sub-hierarchies, one of which is exactly the Toda lattice hierarchy

Minimal string theories and integrable hierarchies

Science.gov (United States)

Iyer, Ramakrishnan

Well-defined, non-perturbative formulations of the physics of string theories in specific minimal or superminimal model backgrounds can be obtained by solving matrix models in the double scaling limit. They provide us with the first examples of completely solvable string theories. Despite being relatively simple compared to higher dimensional critical string theories, they furnish non-perturbative descriptions of interesting physical phenomena such as geometrical transitions between D-branes and fluxes, tachyon condensation and holography. The physics of these theories in the minimal model backgrounds is succinctly encoded in a non-linear differential equation known as the string equation, along with an associated hierarchy of integrable partial differential equations (PDEs). The bosonic string in (2,2m-1) conformal minimal model backgrounds and the type 0A string in (2,4 m) superconformal minimal model backgrounds have the Korteweg-de Vries system, while type 0B in (2,4m) backgrounds has the Zakharov-Shabat system. The integrable PDE hierarchy governs flows between backgrounds with different m. In this thesis, we explore this interesting connection between minimal string theories and integrable hierarchies further. We uncover the remarkable role that an infinite hierarchy of non-linear differential equations plays in organizing and connecting certain minimal string theories non-perturbatively. We are able to embed the type 0A and 0B (A,A) minimal string theories into this single framework. The string theories arise as special limits of a rich system of equations underpinned by an integrable system known as the dispersive water wave hierarchy. We find that there are several other string-like limits of the system, and conjecture that some of them are type IIA and IIB (A,D) minimal string backgrounds. We explain how these and several other string-like special points arise and are connected. In some cases, the framework endows the theories with a non

Gauge and moduli hierarchy in a multiply warped braneworld scenario

International Nuclear Information System (INIS)

Das, Ashmita; SenGupta, Soumitra

2013-01-01

Discovery of Higgs-like boson near the mass scale ∼126 Gev generates renewed interest to the gauge hierarchy problem in the standard model related to the stabilisation of the Higgs mass within Tev scale without any unnatural fine tuning. One of the successful attempts to resolve this problem has been the Randall–Sundrum warped geometry model. Subsequently this 5-dimensional model was extended to a doubly warped 6-dimensional (or higher) model which can offer a geometric explanation of the fermion mass hierarchy in the standard model of elementary particles (D. Choudhury and S. SenGupta, 2007 [1]). In an attempt to address the dark energy issue, we in this work extend such 6-dimensional warped braneworld model to include non-flat 3-branes at the orbifold fixed points such that a small but non-vanishing brane cosmological constant is induced in our observable brane. We show that the requirements of a Planck to Tev scale warping along with a vanishingly small but non-zero cosmological constant on the visible brane with non-hierarchical moduli, each with scale close to Planck length, lead to a scenario where the 3-branes can have energy scales either close to Tev or close to Planck scale. Such a scenario can address both the gauge hierarchy as well as fermion mass hierarchy problem in standard model without introducing hierarchical scales between the two moduli. Thus simultaneous resolutions to the gauge hierarchy problem, fermion mass hierarchy problem and non-hierarchical moduli problem are closely linked with the near flatness condition of our universe.

Making Sense of the Abstraction Hierarchy in the Power Plant Domain

DEFF Research Database (Denmark)

Lind, Morten

2003-01-01

The paper discusses the abstraction hierarchy proposed by Rasmussen [(1986) Information processing and human-machine interaction, North-Holland] for design of human-machine interfaces for supervisory control. The purpose of the abstraction hierarchy is to represent a work domain by multiple levels...... of means-end and part-whole abstractions. It is argued in the paper that the abstraction hierarchy suffers from both methodological and conceptual problems. A cluster of selected problems are analyzed and illustrated by concrete examples from the power plant domain. It is concluded that the semantics...... in the model-building process. It is also pointed out that attempts to clarify the semantics of the abstraction hierarchy will invariably reduce the range of work domains where it can be applied....

Muusikauudised : Lu : k ja Jäääär koos laval. Britney Spears tegutseb. Lenny Kravitz ja Mick Jagger. Kim Wilde

Index Scriptorium Estoniae

2001-01-01

Tartus Sõbra majas toimunud kontserdist. Videost "Britney: The video". Heliplaatidest: "Britney", "The Best of Pink Floyd", "Lenny", Mick Jagger "Goddess In The Doorway", "The Very Best Of Kim Wilde"

Hierarchy of non-glucose sugars in Escherichia coli.

Science.gov (United States)

Aidelberg, Guy; Towbin, Benjamin D; Rothschild, Daphna; Dekel, Erez; Bren, Anat; Alon, Uri

2014-12-24

Understanding how cells make decisions, and why they make the decisions they make, is of fundamental interest in systems biology. To address this, we study the decisions made by E. coli on which genes to express when presented with two different sugars. It is well-known that glucose, E. coli's preferred carbon source, represses the uptake of other sugars by means of global and gene-specific mechanisms. However, less is known about the utilization of glucose-free sugar mixtures which are found in the natural environment of E. coli and in biotechnology. Here, we combine experiment and theory to map the choices of E. coli among 6 different non-glucose carbon sources. We used robotic assays and fluorescence reporter strains to make precise measurements of promoter activity and growth rate in all pairs of these sugars. We find that the sugars can be ranked in a hierarchy: in a mixture of a higher and a lower sugar, the lower sugar system shows reduced promoter activity. The hierarchy corresponds to the growth rate supported by each sugar- the faster the growth rate, the higher the sugar on the hierarchy. The hierarchy is 'soft' in the sense that the lower sugar promoters are not completely repressed. Measurement of the activity of the master regulator CRP-cAMP shows that the hierarchy can be quantitatively explained based on differential activation of the promoters by CRP-cAMP. Comparing sugar system activation as a function of time in sugar pair mixtures at sub-saturating concentrations, we find cases of sequential activation, and also cases of simultaneous expression of both systems. Such simultaneous expression is not predicted by simple models of growth rate optimization, which predict only sequential activation. We extend these models by suggesting multi-objective optimization for both growing rapidly now and preparing the cell for future growth on the poorer sugar. We find a defined hierarchy of sugar utilization, which can be quantitatively explained by

The Emergence and Representation of Knowledge about Social and Nonsocial Hierarchies

Science.gov (United States)

Kumaran, Dharshan; Melo, Hans Ludwig; Duzel, Emrah

2012-01-01

Summary Primates are remarkably adept at ranking each other within social hierarchies, a capacity that is critical to successful group living. Surprisingly little, however, is understood about the neurobiology underlying this quintessential aspect of primate cognition. In our experiment, participants first acquired knowledge about a social and a nonsocial hierarchy and then used this information to guide investment decisions. We found that neural activity in the amygdala tracked the development of knowledge about a social, but not a nonsocial, hierarchy. Further, structural variations in amygdala gray matter volume accounted for interindividual differences in social transitivity performance. Finally, the amygdala expressed a neural signal selectively coding for social rank, whose robustness predicted the influence of rank on participants’ investment decisions. In contrast, we observed that the linear structure of both social and nonsocial hierarchies was represented at a neural level in the hippocampus. Our study implicates the amygdala in the emergence and representation of knowledge about social hierarchies and distinguishes the domain-general contribution of the hippocampus. PMID:23141075

Hamiltonian structure of the integrable coupling of the Jaulent-Miodek hierarchy

International Nuclear Information System (INIS)

Zhang, Yufeng; Fan, Engui

2006-01-01

A scheme for deducing Hamiltonian structures of the higher-dimensional hierarchies of evolution equations is presented which is devoting to obtaining the Hamiltonian structures of integrable coupling of the Jaulent-Miodek hierarchy

Language variety, language hierarchy, and language choice in the international university

DEFF Research Database (Denmark)

Haberland, Hartmut; Mortensen, Janus

2012-01-01

Introduction to thematic issue on Language variety, language hierarchy, and language choice in the international university......Introduction to thematic issue on Language variety, language hierarchy, and language choice in the international university...

An integrable counterpart of the D-AKNS soliton hierarchy from so(3,R)

International Nuclear Information System (INIS)

Ma, Wen-Xiu

2014-01-01

An integrable counterpart of the D-AKNS soliton hierarchy is generated from a matrix spectral problem associated with so(3,R). Hamiltonian structures of the resulting counterpart soliton hierarchy are furnished by using the trace identity, which yields its Liouville integrability. -- Highlights: •Use the Lie algebra so(3,R) to generate a counterpart of the D-AKNS soliton hierarchy. •Generate Hamiltonian structures depending potentials by the trace identity. •Obtain hierarchies of independent commuting symmetries and conserved densities.

Conservation laws and self-consistent sources for a super-CKdV equation hierarchy

International Nuclear Information System (INIS)

Li Li

2011-01-01

From the super-matrix Lie algebras, we consider a super-extension of the CKdV equation hierarchy in the present Letter, and propose the super-CKdV hierarchy with self-consistent sources. Furthermore, we establish the infinitely many conservation laws for the integrable super-CKdV hierarchy.

Conservation laws and self-consistent sources for a super-CKdV equation hierarchy

Energy Technology Data Exchange (ETDEWEB)

Li Li, E-mail: li07099@163.co [College of Maths and Systematic Science, Shenyang Normal University, Shenyang 110034 (China)

2011-03-14

From the super-matrix Lie algebras, we consider a super-extension of the CKdV equation hierarchy in the present Letter, and propose the super-CKdV hierarchy with self-consistent sources. Furthermore, we establish the infinitely many conservation laws for the integrable super-CKdV hierarchy.

The Diversity Education Dilemma: Exposing Status Hierarchies without Reinforcing Them

Science.gov (United States)

Amoroso, Lisa M.; Loyd, Denise Lewin; Hoobler, Jenny M.

2010-01-01

A "diversity education dilemma" occurs when exposure to information concerning status hierarchies, related to demographic and other socially salient identity groups, reinforces those hierarchies in the classroom. Discussions of diversity-related issues in a variety of management courses (e.g., immigrant issues in labor relations, the composition…

"Sundiata, Lion King of Mali." Adapted by Kim Hines, Featuring Griot Alhaji Papa Susso, Cue Sheet for Students.

Science.gov (United States)

Freeman, Aakhu TuahNera

This performance guide is designed for teachers to use with students before and after a performance of "Sundiata: Lion King of Mali," adapted by Kim Hines and featuring Griot Alhaji Papa Susso. The guide, called a "Cuesheet," contains seven activity sheets for use in class, addressing: (1) Sundiata: Man & Myth (discusses…

A role for glucocorticoids in the long-term establishment of a social hierarchy.

Science.gov (United States)

Timmer, Marjan; Sandi, Carmen

2010-11-01

Stress can affect the establishment and maintenance of social hierarchies. In the present study, we investigated the role of increasing corticosterone levels before or just after a first social encounter between two rats of a dyad in the establishment and the long-term maintenance of a social hierarchy. We show that pre-social encounter corticosterone treatment does not affect the outcome of the hierarchy during a first encounter, but induces a long-term memory for the hierarchy when the corticosterone-injected rat becomes dominant during the encounter, but not when it becomes subordinate. Post-social encounter corticosterone leads to a long-term maintenance of the hierarchy only when the subordinate rat of the dyad is injected with corticosterone. This corticosterone effect mimics previously reported actions of stress on the same model and, hence, implicates glucocorticoids in the consolidation of the memory for a recently established hierarchy. Copyright © 2010 Elsevier Ltd. All rights reserved.

Impact of hierarchy upon the values of neutrino mixing parameters

International Nuclear Information System (INIS)

Escamilla-Roa, J.; Ernst, D. J.; Latimer, D. C.

2010-01-01

A neutrino-oscillation analysis is performed of the more finely binned Super-Kamiokande (Super-K) atmospheric, MINOS, and CHOOZ data to examine the effect of neutrino hierarchy in this data set on the value of θ 13 and the deviation of θ 23 from maximal mixing. Exact oscillation probabilities are used, thus incorporating all powers of θ 13 and ε:=θ 23 -π/4. The extracted oscillation parameters are found to be dependent on the hierarchy, particularly for θ 13 . We find, at a 90% confidence level, that these parameters are Δ 32 =2.44 -0.20 +0.26 and 2.48 -0.22 +0.25 x10 -3 eV 2 , ε=θ 23 -π/4=0.06 -0.16 +0.06 and 0.06 -0.17 +0.08 , and θ 13 =-0.07 -0.11 +0.18 and -0.13 -0.16 +0.23 , for the normal and inverted hierarchies, respectively. The inverted hierarchy is preferred at a statistically insignificant level of 0.3σ.

Neutrino mass matrix and hierarchy

International Nuclear Information System (INIS)

Kaus, Peter; Meshkov, Sydney

2003-01-01

We build a model to describe neutrinos based on strict hierarchy, incorporating as much as possible, the latest known data, for Δsol and Δatm, and for the mixing angles determined from neutrino oscillation experiments, including that from KamLAND. Since the hierarchy assumption is a statement about mass ratios, it lets us obtain all three neutrino masses. We obtain a mass matrix, Mν and a mixing matrix, U, where both Mν and U are given in terms of powers of Λ, the analog of the Cabibbo angle λ in the Wolfenstein representation, and two parameters, ρ and κ, each of order one. The expansion parameter, Λ, is defined by Λ2 = m2/m3 = √(Δsol/Δatm) ≅ 0.16, and ρ expresses our ignorance of the lightest neutrino mass m1, (m1 ρΛ4m3), while κ scales s13 to the experimental upper limit, s13 = κΛ2 ≅ 0.16κ. These matrices are similar in structure to those for the quark and lepton families, but with Λ about 1.6 times larger than the λ for the quarks and charged leptons. The upper limit for the effective neutrino mass in double β-decay experiments is 4 x 10-3eV if s13 = 0 and 6 x 10-3eV if s13 is maximal. The model, which is fairly unique, given the hierarchy assumption and the data, is compared to supersymmetric extension and texture zero models of mass generation

A density tensor hierarchy for open system dynamics: retrieving the noise

International Nuclear Information System (INIS)

Adler, Stephen L

2007-01-01

We develop a density tensor hierarchy for open system dynamics that recovers information about fluctuations (or 'noise') lost in passing to the reduced density matrix. For the case of fluctuations arising from a classical probability distribution, the hierarchy is formed from expectations of products of pure state density matrix elements and can be compactly summarized by a simple generating function. For the case of quantum fluctuations arising when a quantum system interacts with a quantum environment in an overall pure state, the corresponding hierarchy is defined as the environmental trace of products of system matrix elements of the full density matrix. Whereas all members of the classical noise hierarchy are system observables, only the lowest member of the quantum noise hierarchy is directly experimentally measurable. The unit trace and idempotence properties of the pure state density matrix imply descent relations for the tensor hierarchies, that relate the order n tensor, under contraction of appropriate pairs of tensor indices, to the order n - 1 tensor. As examples to illustrate the classical probability distribution formalism, we consider a spatially isotropic ensemble of spin-1/2 pure states, a quantum system evolving by an Ito stochastic Schroedinger equation and a quantum system evolving by a jump process Schroedinger equation. As examples to illustrate the corresponding trace formalism in the quantum fluctuation case, we consider the tensor hierarchies for collisional Brownian motion of an infinite mass Brownian particle and for the weak coupling Born-Markov master equation. In different specializations, the latter gives the hierarchies generalizing the quantum optical master equation and the Caldeira-Leggett master equation. As a further application of the density tensor, we contrast stochastic Schroedinger equations that reduce and that do not reduce the state vector, and discuss why a quantum system coupled to a quantum environment behaves like

The Relationship between Incentives to Learn and Maslow's Hierarchy of Needs

Science.gov (United States)

Wu, Wenling

This paper empirically explores lots of students in college for their hierarchy of needs and incentives to learn, and finds the linear relationship between them. With the survey, it's be found that there are some kinds of factors influence the students needs order. The paper gives several diagrams to show these important factors which affect the college students' hierarchy of needs most. The paper also finds the change of the student' hierarchy of needs will affect the variety of incentives to learn. Then the paper develops a model for qualitative analyze this relationship. Numerical examples are used to demonstrate the performance of the model. With this model the correct and useful methods can be easily selected for students to incentive according to their types of hierarchy of needs.

Social hierarchy and depression: the role of emotion suppression.

Science.gov (United States)

Langner, Carrie A; Epel, Elissa S; Matthews, Karen A; Moskowitz, Judith T; Adler, Nancy E

2012-01-01

Position in the social hierarchy is a major determinant of health outcomes. We examined the associations between aspects of social hierarchy and depressive symptoms with a specific focus on one potential psychological mechanism: emotion suppression. Suppressing negative emotion has mental health costs, but individuals with low social power and low social status may use these strategies to avoid conflict. Study 1 assessed perceived social power, tendency to suppress negative emotion, and depressive symptoms in a community sample of women. Low social power was related to greater depressive symptoms, and this relationship was partially mediated by emotion suppression. Study 2 examined education as a proxy for social hierarchy position, anger suppression, and depressive symptoms in a national, longitudinal cohort study (The coronary artery risk development in young adults [CARDIA] study; Cutter et al., 1991). Much as in study 1, low education levels were correlated with greater depressive symptoms, and this relationship was partially mediated by anger suppression. Further, suppression mediated the relationship between low education and subsequent depression up to 15 years later. These findings support the theory that social hierarchy affects mental health in part through a process of emotion suppression.

Dynamic Changes Analysis and Hotspots Detection of Land Use in the Central Core Functional Area of Jing-Jin-Ji from 2000 to 2015 Based on Remote Sensing Data

Directory of Open Access Journals (Sweden)

Yafei Li

2017-01-01

Full Text Available The article uses GIS spatial analysis and grid technologies to study the dynamic changes, hotspot regions, and driving forces in land use of the central core functional area of Jing-Jin-Ji. The research results are as follows: from 2000 to 2015, the main types of land use in the central core functional area of Jing-Jin-Ji are cultivated land, woodland, and built-up land. In the period of 2005–2010, the transfer between built-up land and cultivated land was frequent. The dynamic degree of single land use in unused land was highest. It also finds out that the dynamic degree of the integrated land use from 2005 to 2010 was higher. The center of gravity transfer of the dynamic degree of integrated land use was concentrated in research area. As for the hotspots, their number and scope are increasing, and the positions located in the edge of original main urban area and developed transportation network. The main characteristics of land use dynamic change in the study area are the rapid decrease of cultivated land area and rapid growth of built-up land. The spatial agglomeration of economic factors caused by human activities has an important influence on the spatial and temporal dynamic changes of land use.

Hierarchy of transcriptomic specialization across human cortex captured by myelin map topography

OpenAIRE

Murray, John; Martin, William; Bernacchia, Alberto; Anticevic, Alan; Ji, Jie; Navejar, Natasha; Eckner, William; Demirtas, Murat; Burt, Joshua

2017-01-01

Hierarchy provides a unifying principle for the macroscale organization of anatomical and functional properties across primate cortex, yet the microscale bases of hierarchical specialization across human cortex are poorly understood. Anatomical hierarchy is conventionally informed by invasively measured laminar patterns of long-range cortico-cortical projections, creating the need for a principled proxy measure of hierarchy in humans. Moreover, cortex exhibits a transcriptional architecture c...

The Fragility of Individual-Based Explanations of Social Hierarchies: A Test Using Animal Pecking Orders

Science.gov (United States)

2016-01-01

The standard approach in accounting for hierarchical differentiation in biology and the social sciences considers a hierarchy as a static distribution of individuals possessing differing amounts of some valued commodity, assumes that the hierarchy is generated by micro-level processes involving individuals, and attempts to reverse engineer the processes that produced the hierarchy. However, sufficient experimental and analytical results are available to evaluate this standard approach in the case of animal dominance hierarchies (pecking orders). Our evaluation using evidence from hierarchy formation in small groups of both hens and cichlid fish reveals significant deficiencies in the three tenets of the standard approach in accounting for the organization of dominance hierarchies. In consequence, we suggest that a new approach is needed to explain the organization of pecking orders and, very possibly, by implication, for other kinds of social hierarchies. We develop an example of such an approach that considers dominance hierarchies to be dynamic networks, uses dynamic sequences of interaction (dynamic network motifs) to explain the organization of dominance hierarchies, and derives these dynamic sequences directly from observation of hierarchy formation. We test this dynamical explanation using computer simulation and find a good fit with actual dynamics of hierarchy formation in small groups of hens. We hypothesize that the same dynamic sequences are used in small groups of many other animal species forming pecking orders, and we discuss the data required to evaluate our hypothesis. Finally, we briefly consider how our dynamic approach may be generalized to other kinds of social hierarchies using the example of the distribution of empty gastropod (snail) shells occupied in populations of hermit crabs. PMID:27410230

Soliton solutions of the mixed discrete modified Korteweg-de Vries hierarchy via the inverse scattering transform

International Nuclear Information System (INIS)

Li Qi; Duan Qiuyuan; Zhang Jianbing

2012-01-01

The mixed discrete modified Korteweg-de Vries (mKdV) hierarchy and the Lax pair are derived. The hierarchy related to the Ablowitz-Ladik spectral problem is reduced to the isospectral discrete mKdV hierarchy and to the non-isospectral discrete mKdV hierarchy. N-soliton solutions of the hierarchies are obtained through inverse scattering transform.

An Improved Semidefinite Programming Hierarchy for Testing Entanglement

Science.gov (United States)

Harrow, Aram W.; Natarajan, Anand; Wu, Xiaodi

2017-06-01

We present a stronger version of the Doherty-Parrilo-Spedalieri (DPS) hierarchy of approximations for the set of separable states. Unlike DPS, our hierarchy converges exactly at a finite number of rounds for any fixed input dimension. This yields an algorithm for separability testing that is singly exponential in dimension and polylogarithmic in accuracy. Our analysis makes use of tools from algebraic geometry, but our algorithm is elementary and differs from DPS only by one simple additional collection of constraints.

Earth Effects and Mass Hierarchy with Supernova Neutrinos

International Nuclear Information System (INIS)

Dasgupta, Basudeb

2009-01-01

Collective neutrino flavor transformations take place deep inside a supernova if the neutrino mass hierarchy is inverted, even for extremely small values of θ 13 . We show that the presence (or absence) of Earth matter effects in antineutrino signal is directly related to the absence (or presence) of these collective effects, when the mixing angle θ 13 is small. Thus a neutrino signal from a galactic supernova may enable us to distinguish between the hierarchies even for small values of θ 13 .

N = 4 Toda chain (KdV) hierarchy in N = 4 superspace

International Nuclear Information System (INIS)

Sorin, A.S.

2002-01-01

The Lax pair and Hamiltonian formulations are presented for the N = 4 supersymmetric Toda chain (KdV) hierarchy in N = 4 superspace. The general formulas for an infinite tower of its bosonic flows in terms of the Lax operator in N = 4 superspace are derived, and five real forms of the hierarchy are presented. New N = 4 superfield bases in which the flows are local are discussed. A relation between the two descriptions of the hierarchy in N = 4 superspace used in the literature is established

Topological hierarchy matters — topological matters with superlattices of defects

International Nuclear Information System (INIS)

He Jing; Kou Su-Peng

2016-01-01

Topological insulators/superconductors are new states of quantum matter with metallic edge/surface states. In this paper, we review the defects effect in these topological states and study new types of topological matters — topological hierarchy matters. We find that both topological defects (quantized vortices) and non topological defects (vacancies) can induce topological mid-gap states in the topological hierarchy matters after considering the superlattice of defects. These topological mid-gap states have nontrivial topological properties, including the nonzero Chern number and the gapless edge states. Effective tight-binding models are obtained to describe the topological mid-gap states in the topological hierarchy matters. (topical review)

Exploring memory hierarchy design with emerging memory technologies

CERN Document Server

Sun, Guangyu

2014-01-01

This book equips readers with tools for computer architecture of high performance, low power, and high reliability memory hierarchy in computer systems based on emerging memory technologies, such as STTRAM, PCM, FBDRAM, etc.  The techniques described offer advantages of high density, near-zero static power, and immunity to soft errors, which have the potential of overcoming the “memory wall.”  The authors discuss memory design from various perspectives: emerging memory technologies are employed in the memory hierarchy with novel architecture modification;  hybrid memory structure is introduced to leverage advantages from multiple memory technologies; an analytical model named “Moguls” is introduced to explore quantitatively the optimization design of a memory hierarchy; finally, the vulnerability of the CMPs to radiation-based soft errors is improved by replacing different levels of on-chip memory with STT-RAMs.   ·         Provides a holistic study of using emerging memory technologies i...

Inverted hierarchy and asymptotic freedom in grand unified supersymmetric theories

International Nuclear Information System (INIS)

Aratyn, H.

1983-01-01

The interrelation between an inverted hierarchy mechanism and asymptotic freedom in supersymmetric theories is analyzed in two models for which we performed a detailed analysis of the effective potentials and effective couplings. We find it difficult to accommodate an inverted hierarchy together with asymptotic freedom for the matter-Yukawa couplings. (orig.)

Differences in immunolocalization of Kim-1, RPA-1, and RPA-2 in kidneys of gentamicin-, cisplatin-, and valproic acid-treated rats: potential role of iNOS and nitrotyrosine.

Science.gov (United States)

Zhang, Jun; Goering, Peter L; Espandiari, Parvaneh; Shaw, Martin; Bonventre, Joseph V; Vaidya, Vishal S; Brown, Ronald P; Keenan, Joe; Kilty, Cormac G; Sadrieh, Nakissa; Hanig, Joseph P

2009-08-01

The present study compared the immunolocalization of Kim-1, renal papillary antigen (RPA)-1, and RPA-2 with that of inducible nitric oxide synthase (iNOS) and nitrotyrosine in kidneys of gentamicin sulfate (Gen)- and cisplatin (Cis)-treated rats. The specificity of acute kidney injury (AKI) biomarkers, iNOS, and nitrotyrosine was evaluated by dosing rats with valproic acid (VPA). Sprague-Dawley (SD) rats were injected subcutaneously (sc) with 100 mg/kg/day of Gen for six or fourteen days; a single intraperitoneal (ip) dose of 1, 3, or 6 mg/kg of Cis; or 650 mg/kg/day of VPA (ip) for four days. In Gen-treated rats, Kim-1 was expressed in the epithelial cells, mainly in the S1/S2 segments but less so in the S3 segment, and RPA-1 was increased in the epithelial cells of collecting ducts (CD) in the cortex. Spatial expression of iNOS or nitrotyrosine with Kim-1 or RPA-1 was detected. In Cis-treated rats, Kim-1 was expressed only in the S3 segment cells, and RPA-1 and RPA-2 were increased in the epithelial cells of medullary CD or medullary loop of Henle (LH), respectively. Spatial expression of iNOS or nitrotyrosine with RPA-1 or RPA-2 was also identified. These findings suggest that peroxynitrite formation may be involved in the pathogenesis of Gen and Cis nephrotoxicity and that Kim-1, RPA-1, and RPA-2 have the potential to serve as site-specific biomarkers for Gen or Cis AKI.

Maslow's Hierarchy and Student Retention.

Science.gov (United States)

Brookman, David M.

1989-01-01

Abraham Maslow's hierarchy of needs offers perspective on student motivation and a rationale for college retention programing. Student affairs and faculty interventions addressing student safety needs and engaging students' sense of purpose reinforce persistence. A mentor program is a possible cooperative effort between student personnel and…

Effects of amoxicillin/clavulanic acid on the pharmacokinetics of valproic acid

Directory of Open Access Journals (Sweden)

Lee SY

2015-08-01

Full Text Available Soo-Yun Lee,1 Wooseong Huh,2 Jin Ah Jung,3 Hye Min Yoo,2 Jae-Wook Ko,1,2 Jung-Ryul Kim2,4 1Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, 2Department of Clinical Pharmacology and Therapeutics, Samsung Medical Center, Seoul, 3Department of Clinical Pharmacology, Inje University, Busan Paik Hospital, Busan, 4Department of Clinical Research and Evaluation, SAIHST, Sungkyunkwan University, Seoul, Republic of Korea Abstract: Valproic acid (VPA is mainly metabolized via glucuronide, which is hydrolyzed by β-glucuronidase and undergoes enterohepatic circulation. Amoxicillin/clavulanic acid (AMC administration leads to decreased levels of β-glucuronidase-producing bacteria, suggesting that these antibiotics could interrupt enterohepatic circulation and thereby alter the pharmacokinetics of VPA. This study aimed to evaluate the effects of AMC on the pharmacokinetics of VPA. This was an open-label, two-treatment, one-sequence study in 16 healthy volunteers. Two treatments were evaluated; treatment VPA, in which a single dose of VPA 500 mg was administered, and treatment AMC + VPA, in which multiple doses of AMC 500/125 mg were administered three times daily for 7 days and then a single dose of VPA was administered. Blood samples were collected up to 48 hours. Pharmacokinetic parameters were calculated using noncompartmental methods. Fifteen subjects completed the study. Systemic exposures and peak concentrations of VPA were slightly lower with treatment AMC + VPA than with treatment VPA (AUClast, 851.0 h·mg/L vs 889.6 h·mg/L; Cmax, 52.1 mg/L vs 53.0 mg/L. There were no significant between-treatment effects on pharmacokinetics (95% confidence interval [CI] of AUClast and Cmax (95.7 [85.9–106.5] and 98.3 [91.6–105.6], respectively. Multiple doses of AMC had no significant effects on the pharmacokinetics of VPA; thus, no dose adjustment is necessary. Keywords: drug–drug interaction, pharmacokinetics

Generalized non-linear Schroedinger hierarchy

International Nuclear Information System (INIS)

Aratyn, H.; Gomes, J.F.; Zimerman, A.H.

1994-01-01

The importance in studying the completely integrable models have became evident in the last years due to the fact that those models present an algebraic structure extremely rich, providing the natural scenery for solitons description. Those models can be described through non-linear differential equations, pseudo-linear operators (Lax formulation), or a matrix formulation. The integrability implies in the existence of a conservation law associated to each of degree of freedom. Each conserved charge Q i can be associated to a Hamiltonian, defining a time evolution related to to a time t i through the Hamilton equation ∂A/∂t i =[A,Q i ]. Particularly, for a two-dimensions field theory, infinite degree of freedom exist, and consequently infinite conservation laws describing the time evolution in space of infinite times. The Hamilton equation defines a hierarchy of models which present a infinite set of conservation laws. This paper studies the generalized non-linear Schroedinger hierarchy

Cognitive Hierarchy Theory and Two-Person Games

Directory of Open Access Journals (Sweden)

Carlos Gracia-Lázaro

2017-01-01

Full Text Available The outcome of many social and economic interactions, such as stock-market transactions, is strongly determined by the predictions that agents make about the behavior of other individuals. Cognitive hierarchy theory provides a framework to model the consequences of forecasting accuracy that has proven to fit data from certain types of game theory experiments, such as Keynesian beauty contests and entry games. Here, we focus on symmetric two-player-two-action games and establish an algorithm to find the players’ strategies according to the cognitive hierarchy approach. We show that the snowdrift game exhibits a pattern of behavior whose complexity grows as the cognitive levels of players increases. In addition to finding the solutions up to the third cognitive level, we demonstrate, in this theoretical frame, two new properties of snowdrift games: (i any snowdrift game can be characterized by only a parameter, its class; (ii they are anti-symmetric with respect to the diagonal of the pay-off’s space. Finally, we propose a model based on an evolutionary dynamics that captures the main features of the cognitive hierarchy theory.

Collaborative hierarchy maintains cooperation in asymmetric games.

Science.gov (United States)

Antonioni, Alberto; Pereda, María; Cronin, Katherine A; Tomassini, Marco; Sánchez, Angel

2018-03-29

The interplay of social structure and cooperative behavior is under much scrutiny lately as behavior in social contexts becomes increasingly relevant for everyday life. Earlier experimental work showed that the existence of a social hierarchy, earned through competition, was detrimental for the evolution of cooperative behaviors. Here, we study the case in which individuals are ranked in a hierarchical structure based on their performance in a collective effort by having them play a Public Goods Game. In the first treatment, participants are ranked according to group earnings while, in the second treatment, their rankings are based on individual earnings. Subsequently, participants play asymmetric Prisoner's Dilemma games where higher-ranked players gain more than lower ones. Our experiments show that there are no detrimental effects of the hierarchy formed based on group performance, yet when ranking is assigned individually we observe a decrease in cooperation. Our results show that different levels of cooperation arise from the fact that subjects are interpreting rankings as a reputation which carries information about which subjects were cooperators in the previous phase. Our results demonstrate that noting the manner in which a hierarchy is established is essential for understanding its effects on cooperation.

Breaking through the Glass Ceiling: Consumers in Mental Health Organisations' Hierarchies.

Science.gov (United States)

Scholz, Brett; Bocking, Julia; Happell, Brenda

2017-05-01

Contemporary mental health policies call for consumers to be engaged in all levels of mental health service planning, implementation, and delivery. Critical approaches to traditional healthcare hierarchies can effectively challenge barriers to better engagement with consumers in mental health organisations. This qualitative exploratory study analyses how particular strategies for consumer leadership facilitate or hinder relationships between consumers and mental health services, and how these strategies influence hierarchical structures. Fourteen participants from a range of mental health organisations were interviewed. These interviews were analysed using thematic analytic and discursive psychological techniques. The findings highlight several benefits of having consumers within mental health organisational hierarchies, and elaborate on ways that employees within mental health services can support integration of consumers into existing hierarchies. Specific barriers to consumers in hierarchies are discussed, including a lack of clarity of structures and roles within hierarchies, and resistance to consumers reaching the highest levels of leadership within organisations. Alternative hierarchical models which privilege consumers' control over resources and power are also discussed. Mental health organisations are encouraged to integrate consumer leaders into their hierarchical structures to improve their organisational offerings, their reputation, and their service innovation.

Detecting Role Errors in the Gene Hierarchy of the NCI Thesaurus

Directory of Open Access Journals (Sweden)

Yehoshua Perl

2008-01-01

Full Text Available Gene terminologies are playing an increasingly important role in the ever-growing field of genomic research. While errors in large, complex terminologies are inevitable, gene terminologies are even more susceptible to them due to the rapid growth of genomic knowledge and the nature of its discovery. It is therefore very important to establish quality- assurance protocols for such genomic-knowledge repositories. Different kinds of terminologies oftentimes require auditing methodologies adapted to their particular structures. In light of this, an auditing methodology tailored to the characteristics of the NCI Thesaurus’s (NCIT’s Gene hierarchy is presented. The Gene hierarchy is of particular interest to the NCIT’s designers due to the primary role of genomics in current cancer research. This multiphase methodology focuses on detecting role-errors, such as missing roles or roles with incorrect or incomplete target structures, occurring within that hierarchy. The methodology is based on two kinds of abstraction networks, called taxonomies, that highlight the role distribution among concepts within the IS-A (subsumption hierarchy. These abstract views tend to highlight portions of the hierarchy having a higher concentration of errors. The errors found during an application of the methodology

Central extensions of cotangent universal hierarchy: (2+1)-dimensional bi-Hamiltonian systems

International Nuclear Information System (INIS)

Sergyeyev, Artur; Szablikowski, Blazej M.

2008-01-01

We introduce the cotangent universal hierarchy that extends the universal hierarchy from [L. Martinez Alonso, A.B. Shabat, Phys. Lett. A 300 (1) (2002) 58, (nlin.SI/0202008); A.B. Shabat, Theor. Math. Phys. 136 (2003) 1066; L. Martinez Alonso, A.B. Shabat, J. Nonlinear Math. Phys. 10 (2) (2003) 229, (nlin.SI/0310036); L. Martinez Alonso, A.B. Shabat, Theor. Math. Phys. 140 (2) (2004) 1073, (nlin.SI/0312043); A. Shabat, J. Nonlinear Math. Phys. 12 (Suppl. 1) (2005) 614]. Then we construct a (2+1)-dimensional double central extension of the cotangent universal hierarchy and show that this extension is bi-Hamiltonian. This yields, as a byproduct, the central extension of the original universal hierarchy

Dunajski–Tod equation and reductions of the generalized dispersionless 2DTL hierarchy

Energy Technology Data Exchange (ETDEWEB)

Bogdanov, L.V., E-mail: leonid@landau.ac.ru [L.D. Landau ITP RAS, Moscow (Russian Federation)

2012-10-01

We transfer the scheme for constructing differential reductions recently developed for the Manakov–Santini hierarchy to the case of the two-component generalization of dispersionless 2DTL hierarchy. We demonstrate that the equation arising as a result of the simplest reduction is equivalent (up to a Legendre type transformation) to the Dunajski–Tod equation, locally describing general ASD vacuum metric with conformal symmetry. We consider higher reductions and corresponding reduced hierarchies also. -- Highlights: ► We introduce a differential reduction for the two-component d2DTL equation. ► We demonstrate that it is connected with ASD vacuum metric with conformal symmetry. ► We construct higher reductions and the reduced hierarchies.

The dynamic nature of social hierarchies : The role of norm violations and hierarchical concerns

NARCIS (Netherlands)

Stamkou, E.

2018-01-01

Social hierarchy is a fundamental feature of social relations. Hierarchies are appealing psychologically because they facilitate group functioning, which explains why they tend to be reinforced and perpetuated. Hierarchies, however, can also become unstable and eventually undergo change because

Detecting Hidden Hierarchy of Non Hierarchical Terrorist Networks

DEFF Research Database (Denmark)

Memon, Nasrullah

measures (and combinations of them) to identify key players (important nodes) in terrorist networks. Our recently introduced techniques and algorithms (which are also implemented in the investigative data mining toolkit known as iMiner) will be particularly useful for law enforcement agencies that need...... to analyze terrorist networks and prioritize their targets. Applying recently introduced mathematical methods for constructing the hidden hierarchy of "nonhierarchical" terrorist networks; we present case studies of the terrorist attacks occurred / planned in the past, in order to identify hidden hierarchy...

Hierarchy plus anarchy in quark masses and mixings

International Nuclear Information System (INIS)

Aguilar-Saavedra, J.A.

2003-01-01

We introduce a parametrization of the effect of unknown corrections from new physics on quark and lepton mass matrices. This parametrization is used in order to study how the hierarchies of quark masses and mixing angles are modified by random perturbations of the Yukawa matrices. We discuss several examples of flavor relations predicted by different textures, analyzing how these relations are influenced by the random perturbations. We also comment on the unlikely possibility that unknown corrections contribute significantly to the hierarchy of masses and mixings

Contrastive hierarchies, privative features, and Portuguese vowels

Directory of Open Access Journals (Sweden)

Joaquim Brandão de Carvalho

2011-01-01

Full Text Available Dresher’s (2009 Contrastive hierarchy theory (CHT is intended to provide a unified account of both sides of phonological primes: contrastivity and behaviour. This article explores the point and the possibility of extending CHT, which is based on binary features, to a system of monovalent elements that is much indebted to Schane’s (1984 Particle Phonology. It shows how several aspects of the phonology of European Portuguese nuclei that seem prima facie independent from one another – such as reduction patterns and the inventory of diphthongs and nasal vowels – are constrained by element hierarchy, and, thus, receive a unitary account.

K-theoretic Gromov-Witten invariants in genus 0 and integrable hierarchies

Science.gov (United States)

Milanov, Todor; Tonita, Valentin

2018-03-01

We prove that the genus 0 invariants in K-theoretic Gromov-Witten theory are governed by an integrable hierarchy of hydrodynamic type. If the K-theoretic quantum product is semisimple, then we also prove the completeness of the hierarchy.

Scale hierarchy in high-temperature QCD

CERN Document Server

Akerlund, Oscar

2013-01-01

Because of asymptotic freedom, QCD becomes weakly interacting at high temperature: this is the reason for the transition to a deconfined phase in Yang-Mills theory at temperature $T_c$. At high temperature $T \\gg T_c$, the smallness of the running coupling $g$ induces a hierachy betwen the "hard", "soft" and "ultrasoft" energy scales $T$, $g T$ and $g^2 T$. This hierarchy allows for a very successful effective treatment where the "hard" and the "soft" modes are successively integrated out. However, it is not clear how high a temperature is necessary to achieve such a scale hierarchy. By numerical simulations, we show that the required temperatures are extremely high. Thus, the quantitative success of the effective theory down to temperatures of a few $T_c$ appears surprising a posteriori.

Super Hamiltonian structure of the even order SKP hierarchy without reduction

International Nuclear Information System (INIS)

Watanabe, Yoshihide

1987-01-01

The super Hamiltonian operator which is different from that of Manin and Radul is derived from the even order SKP hierarchy without reduction and in terms of the operator, the equation in the hierarchy is written in a Hamiltonian form. (orig.)

The Virasoro algebra in integrable hierarchies and the method of matrix models

International Nuclear Information System (INIS)

Semikhatov, A.M.

1992-01-01

The action of the Virasoro algebra on hierarchies of nonlinear integrable equations, and also the structure and consequences of Virasoro constraints on these hierarchies, are studied. It is proposed that a broad class of hierarchies, restricted by Virasoro constraints, can be defined in terms of dressing operators hidden in the structure of integrable systems. The Virasoro-algebra representation constructed on the dressing operators displays a number of analogies with structures in conformal field theory. The formulation of the Virasoro constraints that stems from this representation makes it possible to translate into the language of integrable systems a number of concepts from the method of the 'matrix models' that describe nonperturbative quantum gravity, and, in particular, to realize a 'hierarchical' version of the double scaling limit. From the Virasoro constraints written in terms of the dressing operators generalized loop equations are derived, and this makes it possible to do calculations on a reconstruction of the field-theoretical description. The reduction of the Kadomtsev-Petviashvili (KP) hierarchy, subject to Virasoro constraints, to generalized Korteweg-deVries (KdV) hierarchies is implemented, and the corresponding representation of the Virasoro algebra on these hierarchies is found both in the language of scalar differential operators and in the matrix formalism of Drinfel'd and Sokolov. The string equation in the matrix formalism does not replicate the structure of the scalar string equation. The symmetry algebras of the KP and N-KdV hierarchies restricted by Virasoro constraints are calculated: A relationship is established with algebras from the family W ∞ (J) of infinite W-algebras

Zipf’s law, 1/f noise, and fractal hierarchy

International Nuclear Information System (INIS)

Chen Yanguang

2012-01-01

Highlights: ► I developed a general scaling method based on hierarchies of cites. ► Hierarchy is classified into three types based on monofractal and multifractals. ► Zipf’s law can be used to estimate the capacity dimension of a multifractal set. ► I derive the self-similar hierarchy from the rank-size distribution. ► The hierarchical scaling method can be applied to the 1/f spectra. - Abstract: Fractals, 1/f noise, and Zipf’s laws are frequently observed within the natural living world as well as in social institutions, representing three signatures of complex systems. All these observations are associated with scaling laws and therefore have created much research interest in many diverse scientific circles. However, the inherent relationships between these scaling phenomena are not yet clear. In this paper, theoretical demonstration and mathematical experiments based on urban studies are employed to reveal the analogy between fractal patterns, 1/f spectra, and the Zipf distribution. First, the multifractal process empirically suggests the Zipf distribution. Second, a 1/f spectrum is mathematically identical to Zipf’s law. Third, both 1/f spectra and Zipf’s law can be converted into a self-similar hierarchy. Fourth, fractals, 1/f spectra, Zipf’s law can be rescaled with similar exponential laws and power laws. The self-similar hierarchy is a more general scaling method which can be used to unify different scaling phenomena and rules in both physical and social systems such as cities, rivers, earthquakes, fractals, 1/f noise, and rank-size distributions. The mathematical laws of this hierarchical structure can provide us with a holistic perspective of looking at complexity and complex systems.

Can nonstandard interactions jeopardize the hierarchy sensitivity of DUNE?

Science.gov (United States)

Deepthi, K. N.; Goswami, Srubabati; Nath, Newton

2017-10-01

We study the effect of nonstandard interactions (NSIs) on the propagation of neutrinos through the Earth's matter and how it affects the hierarchy sensitivity of the DUNE experiment. We emphasize the special case when the diagonal NSI parameter ɛe e=-1 , nullifying the standard matter effect. We show that if, in addition, C P violation is maximal then this gives rise to an exact intrinsic hierarchy degeneracy in the appearance channel, irrespective of the baseline and energy. Introduction of the off diagonal NSI parameter, ɛe τ, shifts the position of this degeneracy to a different ɛe e. Moreover the unknown magnitude and phases of the off diagonal NSI parameters can give rise to additional degeneracies. Overall, given the current model independent limits on NSI parameters, the hierarchy sensitivity of DUNE can get seriously impacted. However, a more precise knowledge of the NSI parameters, especially ɛe e, can give rise to an improved sensitivity. Alternatively, if a NSI exists in nature, and still DUNE shows hierarchy sensitivity, certain ranges of the NSI parameters can be excluded. Additionally, we briefly discuss the implications of ɛe e=-1 (in the Earth) on the Mikheyev-Smirnov-Wolfenstein effect in the Sun.

Common Origin for Neutrino Anarchy and Charged Hierarchies

International Nuclear Information System (INIS)

Agashe, Kaustubh; Okui, Takemichi; Sundrum, Raman

2009-01-01

The generation of exponential flavor hierarchies from extra-dimensional wave function overlaps is reexamined. We find, surprisingly, that the coexistence of anarchic fermion mass matrices with such hierarchies is intrinsic and natural to this setting. The salient features of charged fermion and neutrino masses and mixings can thereby be captured within a single framework. Both Dirac and Majorana neutrinos can be realized. Implications for a variety of weak-scale scenarios, including warped compactification and supersymmetry, are discussed. When the new weak-scale physics is sensitive to the origin of flavor structure, Dirac neutrinos are preferred

The super W∞ symmetry of the Manin-Radul super KP hierarchy

International Nuclear Information System (INIS)

Das, A.; Sin, S.J.

1991-11-01

We show that the Manin-Radul super KP hierarchy is invariant under super W ∞ transformations. These transformations are characterized by time dependent flows which commute with the usual flows generated by the conserved quantities of the super KP hierarchy. (author). 16 refs

Brane world model and hierarchy problem

International Nuclear Information System (INIS)

Alba, V.

2007-01-01

In this paper I wrote description of Kaluza-Klein model. Also I wrote how we can solve the hierarchy problem in Randall-Sundrum model. In fact, it's my motivation to study this part of theoretical physics

Transcriptional control of the isoeugenol monooxygenase of Pseudomonas nitroreducens Jin1 in Escherichia coli.

Science.gov (United States)

Ryu, Ji-Young; Seo, Jiyoung; Ahn, Joong-Hoon; Sadowsky, Michael J; Hur, Hor-Gil

2012-01-01

Vanillin is one of the most valuable compounds in the flavoring and fragrance industries, and many attempts to produce natural vanillin have been made in recent years. Isoeugenol monooxygenase (Iem) converts the phenylpropanoid compound isoeugenol to vanillin. In Pseudomonas nitroreducens Jin1, the positive regulatory protein IemR is divergently expressed from Iem, and the promoter region is located between the genes. In this study, we investigated the transcriptional regulation of iem in Escherichia coli. We focused on inducers and regulatory protein IemR. Transcription of iem was found to be dependent on the amounts of isoeugenol and IemR. Isoeugenol was found to be the best inducer of iem, followed by trans-anethole, which induced iem to 58% of the transcription level observed for isoeugenol. Overproduction of IemR in E. coli significantly increased the transcription of iem, up to 96-fold, even in the absence of isoeugenol, as compared to basally expressed IemR. Results of this study indicate that the transcription of iem iss dependent on the type of inducers and on IemR. They should contribute to the development of bioengineering strategies for increased production of vanillin through high-level expression of the isoeugenol monooxygenase gene in microorganisms.

Science Museum Exhibits' Summative Evaluation with Knowledge Hierarchy Method

Science.gov (United States)

Yasar, Erkan; Gurel, Cem

2016-01-01

It is aimed in this research to measure via knowledge hierarchy the things regarding exhibit themes learned by the visitors of the exhibits and compare them with the purpose that the exhibits are designed for, thereby realizing a summative evaluation of the exhibits by knowledge hierarchy method. The research has been conducted in a children's…

The fluency of social hierarchy: the ease with which hierarchical relationships are seen, remembered, learned, and liked.

Science.gov (United States)

Zitek, Emily M; Tiedens, Larissa Z

2012-01-01

We tested the hypothesis that social hierarchies are fluent social stimuli; that is, they are processed more easily and therefore liked better than less hierarchical stimuli. In Study 1, pairs of people in a hierarchy based on facial dominance were identified faster than pairs of people equal in their facial dominance. In Study 2, a diagram representing hierarchy was memorized more quickly than a diagram representing equality or a comparison diagram. This faster processing led the hierarchy diagram to be liked more than the equality diagram. In Study 3, participants were best able to learn a set of relationships that represented hierarchy (asymmetry of power)--compared to relationships in which there was asymmetry of friendliness, or compared to relationships in which there was symmetry--and this processing ease led them to like the hierarchy the most. In Study 4, participants found it easier to make decisions about a company that was more hierarchical and thus thought the hierarchical organization had more positive qualities. In Study 5, familiarity as a basis for the fluency of hierarchy was demonstrated by showing greater fluency for male than female hierarchies. This study also showed that when social relationships are difficult to learn, people's preference for hierarchy increases. Taken together, these results suggest one reason people might like hierarchies--hierarchies are easy to process. This fluency for social hierarchies might contribute to the construction and maintenance of hierarchies.

On a class of reductions of the Manakov-Santini hierarchy connected with the interpolating system

International Nuclear Information System (INIS)

Bogdanov, L V

2010-01-01

Using the Lax-Sato formulation of the Manakov-Santini hierarchy, we introduce a class of reductions such that the zero-order reduction of this class corresponds to the dKP hierarchy, and the first-order reduction gives the hierarchy associated with the interpolating system introduced by Dunajski. We present the Lax-Sato form of a reduced hierarchy for the interpolating system and also for the reduction of arbitrary order. Similar to the dKP hierarchy, the Lax-Sato equations for L (the Lax function) split from the Lax-Sato equations for M (the Orlov function) due to the reduction, and the reduced hierarchy for an arbitrary order of reduction is defined by Lax-Sato equations for L only. A characterization of the class of reductions in terms of the dressing data is given. We also consider a waterbag reduction of the interpolating system hierarchy, which defines (1+1)-dimensional systems of hydrodynamic type.

Quadratic Hierarchy Flavor Rule as the Origin of Dirac CP-Violating Phases

OpenAIRE

Lipmanov, E. M.

2007-01-01

The premise of an organizing quadratic hierarchy rule in lepton-quark flavor physics was used earlier for explanation of the hierarchy patterns of four generic pairs of flavor quantities 1) charged-lepton and 2) neutrino deviations from mass-degeneracy, 3) deviations of lepton mixing from maximal magnitude and 4) deviations of quark mixing from minimal one. Here it is shown that the quadratic hierarchy equation that is uniquely related to three flavor particle generations may have yet another...

Consultancy services and the urban hierarchy in Western Europe

OpenAIRE

P W Daniels; J H J Van Dinteren; M C Monnayer

1992-01-01

A cross-national survey of the relationship between the evolving organisation and structure of consultancy service enterprises and the urban hierarchy in Europe has been undertaken. Primate cities in Europe are still the preeminent foci for business services performing strong national and international control. The relationship between markets for consultancy services and the urban hierarchy is complex, but it is possible to suggest a typology of firms on the basis of client characteristics a...

Social Hierarchy and Depression: The Role of Emotion Suppression

OpenAIRE

Langner, Carrie A.; Epel, Elissa; Matthews, Karen; Moskowitz, Judith T.; Adler, Nancy

2012-01-01

Position in the social hierarchy is a major determinant of health outcomes. We examined the associations between aspects of social hierarchy and depressive symptoms with a specific focus on one potential psychological mechanism: emotion suppression. Suppressing negative emotion has mental health costs, but individuals with low social power and low social status may use these strategies to avoid conflict. Study 1 assessed perceived social power, tendency to suppress negative emotion, and depre...

A Centerless Virasoro Algebra of Master Symmetries for the Ablowitz-Ladik Hierarchy

Directory of Open Access Journals (Sweden)

Luc Haine

2013-12-01

Full Text Available We show that the (semi-infinite Ablowitz-Ladik (AL hierarchy admits a centerless Virasoro algebra of master symmetries in the sense of Fuchssteiner [Progr. Theoret. Phys. 70 (1983, 1508-1522]. An explicit expression for these symmetries is given in terms of a slight generalization of the Cantero, Moral and Velázquez (CMV matrices [Linear Algebra Appl. 362 (2003, 29-56] and their action on the tau-functions of the hierarchy is described. The use of the CMV matrices turns out to be crucial for obtaining a Lax pair representation of the master symmetries. The AL hierarchy seems to be the first example of an integrable hierarchy which admits a full centerless Virasoro algebra of master symmetries, in contrast with the Toda lattice and Korteweg-de Vries hierarchies which possess only ''half of'' a Virasoro algebra of master symmetries, as explained in Adler and van Moerbeke [Duke Math. J. 80 (1995, 863-911], Damianou [Lett. Math. Phys. 20 (1990, 101-112] and Magri and Zubelli [Comm. Math. Phys. 141 (1991, 329-351].

A new six-component super soliton hierarchy and its self-consistent sources and conservation laws

International Nuclear Information System (INIS)

Wei Han-yu; Xia Tie-cheng

2016-01-01

A new six-component super soliton hierarchy is obtained based on matrix Lie super algebras. Super trace identity is used to furnish the super Hamiltonian structures for the resulting nonlinear super integrable hierarchy. After that, the self-consistent sources of the new six-component super soliton hierarchy are presented. Furthermore, we establish the infinitely many conservation laws for the integrable super soliton hierarchy. (paper)

Neutrino mass hierarchy and δCP investigation within the biprobability (P-PT) plane

International Nuclear Information System (INIS)

Singh, Mandip

2016-01-01

This article illustrates the possibility of investigating the mass hierarchy and CP-violating phase δ CP in the context of CP trajectory diagrams in the biprobability plane. The separation between the normal mass hierarchy (NH) and inverted mass hierarchy (IH) CP trajectory ellipses in the P-P T plane seems to be very promising as a means of investigating the mass hierarchy. An illustration of the separation between the two hierarchy ellipses in the E-L plane is very helpful to cover all the desired baselines and beam energies and also to analyze the benefits and drawbacks in one step. If we know the mass hierarchy, then, from the large sizes of CP trajectory ellipses that are possible at appropriately long baselines (L) and at specific values of beam energy (E), it becomes possible to investigate at least narrow ranges of the CP/T-violating phase δ CP . The possibility of more than one set of (θ 13 ,δ CP ) parameters corresponding to any chosen coordinate in the P-P T plane, known as parameter degeneracy, may hinder the exact determination of the mass hierarchy as well as the δ CP value. To circumvent this degeneracy in the (θ 13 ,δ CP ) parameter space, in the case of opposite-sign solutions corresponding to the NH and IH cases, sufficiently long baselines are needed, so as to separate the opposite hierarchy ellipses to create an observable separation; in the case of same-sign solutions corresponding to either NH or IH, we need to choose an experimental configuration with L≃2535 km, E≃5 GeV for the n=1 scenario

Integral equation hierarchy for continuum percolation

International Nuclear Information System (INIS)

Given, J.A.

1988-01-01

In this thesis a projection operator technique is presented that yields hierarchies of integral equations satisfied exactly by the n-point connectedness functions in a continuum version of the site-bond percolation problem. The n-point connectedness functions carry the same structural information for a percolation problem as then-point correlation functions do for a thermal problem. This method extends the Potts model mapping of Fortuin and Kastelyn to the continuum by exploiting an s-state generalization of the Widom-Rowlinson model, a continuum model for phase separation. The projection operator technique is used to produce an integral equation hierarchy for percolation similar to the Born-Green heirarchy. The Kirkwood superposition approximation (SA) is extended to percolation in order to close this hierarchy and yield a nonlinear integral equation for the two-point connectedness function. The fact that this function, in the SA, is the analytic continuation to negative density of the two-point correlation function in a corresponding thermal problem is discussed. The BGY equation for percolation is solved numerically, both by an expansion in powers of the density, and by an iterative technique due to Kirkwood. It is argued both analytically and numerically, that the BYG equation for percolation, unlike its thermal counterpart, shows non-classical critical behavior, with η = 1 and γ = 0.05 ± .1. Finally a sequence of refinements to the superposition approximations based in the theory of fluids by Rice and Lekner is discussed

Hierarchy stability moderates the effect of status on stress and performance in humans.

Science.gov (United States)

Knight, Erik L; Mehta, Pranjal H

2017-01-03

High social status reduces stress responses in numerous species, but the stress-buffering effect of status may dissipate or even reverse during times of hierarchical instability. In an experimental test of this hypothesis, 118 participants (57.3% female) were randomly assigned to a high- or low-status position in a stable or unstable hierarchy and were then exposed to a social-evaluative stressor (a mock job interview). High status in a stable hierarchy buffered stress responses and improved interview performance, but high status in an unstable hierarchy boosted stress responses and did not lead to better performance. This general pattern of effects was observed across endocrine (cortisol and testosterone), psychological (feeling in control), and behavioral (competence, dominance, and warmth) responses to the stressor. The joint influence of status and hierarchy stability on interview performance was explained by feelings of control and testosterone reactivity. Greater feelings of control predicted enhanced interview performance, whereas increased testosterone reactivity predicted worse performance. These results provide direct causal evidence that high status confers adaptive benefits for stress reduction and performance only when the social hierarchy is stable. When the hierarchy is unstable, high status actually exacerbates stress responses.

Probing neutrino mass hierarchy by comparing the charged-current and neutral-current interaction rates of supernova neutrinos

Energy Technology Data Exchange (ETDEWEB)

Lai, Kwang-Chang [Center for General Education, Chang Gung University,Kwei-Shan, Taoyuan, 333, Taiwan (China); Leung Center for Cosmology and Particle Astrophysics (LeCosPA), National Taiwan University, Taipei, 106, Taiwan (China); Lee, Fei-Fan [Institute of Physics, National Chiao Tung University,Hsinchu, 300, Taiwan (China); Lee, Feng-Shiuh [Department of Electrophysics, National Chiao Tung University,Hsinchu, 300, Taiwan (China); Lin, Guey-Lin [Leung Center for Cosmology and Particle Astrophysics (LeCosPA), National Taiwan University, Taipei, 106, Taiwan (China); Institute of Physics, National Chiao Tung University,Hsinchu, 300, Taiwan (China); Liu, Tsung-Che [Leung Center for Cosmology and Particle Astrophysics (LeCosPA), National Taiwan University, Taipei, 106, Taiwan (China); Yang, Yi [Department of Electrophysics, National Chiao Tung University,Hsinchu, 300, Taiwan (China)

2016-07-22

The neutrino mass hierarchy is one of the neutrino fundamental properties yet to be determined. We introduce a method to determine neutrino mass hierarchy by comparing the interaction rate of neutral current (NC) interactions, ν(ν-bar)+p→ν(ν-bar)+p, and inverse beta decays (IBD), ν-bar{sub e}+p→n+e{sup +}, of supernova neutrinos in scintillation detectors. Neutrino flavor conversions inside the supernova are sensitive to neutrino mass hierarchy. Due to Mikheyev-Smirnov-Wolfenstein effects, the full swapping of ν-bar{sub e} flux with the ν-bar{sub x} (x=μ, τ) one occurs in the inverted hierarchy, while such a swapping does not occur in the normal hierarchy. As a result, more high energy IBD events occur in the detector for the inverted hierarchy than the high energy IBD events in the normal hierarchy. By comparing IBD interaction rate with the mass hierarchy independent NC interaction rate, one can determine the neutrino mass hierarchy.

Probing neutrino mass hierarchy by comparing the charged-current and neutral-current interaction rates of supernova neutrinos

Science.gov (United States)

Lai, Kwang-Chang; Lee, Fei-Fan; Lee, Feng-Shiuh; Lin, Guey-Lin; Liu, Tsung-Che; Yang, Yi

2016-07-01

The neutrino mass hierarchy is one of the neutrino fundamental properties yet to be determined. We introduce a method to determine neutrino mass hierarchy by comparing the interaction rate of neutral current (NC) interactions, ν(bar nu) + p → ν(bar nu) + p, and inverse beta decays (IBD), bar nue + p → n + e+, of supernova neutrinos in scintillation detectors. Neutrino flavor conversions inside the supernova are sensitive to neutrino mass hierarchy. Due to Mikheyev-Smirnov-Wolfenstein effects, the full swapping of bar nue flux with the bar nux (x = μ, τ) one occurs in the inverted hierarchy, while such a swapping does not occur in the normal hierarchy. As a result, more high energy IBD events occur in the detector for the inverted hierarchy than the high energy IBD events in the normal hierarchy. By comparing IBD interaction rate with the mass hierarchy independent NC interaction rate, one can determine the neutrino mass hierarchy.

Probing neutrino mass hierarchy by comparing the charged-current and neutral-current interaction rates of supernova neutrinos

International Nuclear Information System (INIS)

Lai, Kwang-Chang; Lee, Fei-Fan; Lee, Feng-Shiuh; Lin, Guey-Lin; Liu, Tsung-Che; Yang, Yi

2016-01-01

The neutrino mass hierarchy is one of the neutrino fundamental properties yet to be determined. We introduce a method to determine neutrino mass hierarchy by comparing the interaction rate of neutral current (NC) interactions, ν(ν-bar)+p→ν(ν-bar)+p, and inverse beta decays (IBD), ν-bar_e+p→n+e"+, of supernova neutrinos in scintillation detectors. Neutrino flavor conversions inside the supernova are sensitive to neutrino mass hierarchy. Due to Mikheyev-Smirnov-Wolfenstein effects, the full swapping of ν-bar_e flux with the ν-bar_x (x=μ, τ) one occurs in the inverted hierarchy, while such a swapping does not occur in the normal hierarchy. As a result, more high energy IBD events occur in the detector for the inverted hierarchy than the high energy IBD events in the normal hierarchy. By comparing IBD interaction rate with the mass hierarchy independent NC interaction rate, one can determine the neutrino mass hierarchy.

Integrable relativistic Toda type lattice hierarchies, associated coupling systems and the Darboux transformation

International Nuclear Information System (INIS)

Yang Hongxiang; Xu Xixiang; Sun Yepeng; Ding Haiyong

2006-01-01

Starting from a discrete isospectral problem, integrable positive and negative relativistic Toda type lattice hierarchies are derived. The two lattice hierarchies are proven to have discrete zero-curvature representations associated with a discrete spectral problem, and the positive and negative lattice hierarchies correspond to positive and negative power expansions of Lax operators with respect to the spectral parameter, respectively. The integrable positive and negative coupling systems of the resulting hierarchies are constructed through enlarging Lax pairs. In addition, with the help of gauge transformations of spectral problems, a Darboux transformation is established for the relativistic Toda type lattice. As an application, an exact solution is explicitly presented

A real nonlinear integrable couplings of continuous soliton hierarchy and its Hamiltonian structure

International Nuclear Information System (INIS)

Yu Fajun

2011-01-01

Some integrable coupling systems of existing papers are linear integrable couplings. In the Letter, beginning with Lax pairs from special non-semisimple matrix Lie algebras, we establish a scheme for constructing real nonlinear integrable couplings of continuous soliton hierarchy. A direct application to the AKNS spectral problem leads to a novel nonlinear integrable couplings, then we consider the Hamiltonian structures of nonlinear integrable couplings of AKNS hierarchy with the component-trace identity. - Highlights: → We establish a scheme to construct real nonlinear integrable couplings. → We obtain a novel nonlinear integrable couplings of AKNS hierarchy. → Hamiltonian structure of nonlinear integrable couplings AKNS hierarchy is presented.

Hierarchy of rational order families of chaotic maps with an invariant ...

Indian Academy of Sciences (India)

We introduce an interesting hierarchy of rational order chaotic maps that possess an invariant measure. In contrast to the previously introduced hierarchy of chaotic maps [1–5], with merely entropy production, the rational order chaotic maps can simultaneously produce and consume entropy. We compute the ...

A consistent hierarchy of generalized kinetic equation approximations to the master equation applied to surface catalysis.

Science.gov (United States)

Herschlag, Gregory J; Mitran, Sorin; Lin, Guang

2015-06-21

We develop a hierarchy of approximations to the master equation for systems that exhibit translational invariance and finite-range spatial correlation. Each approximation within the hierarchy is a set of ordinary differential equations that considers spatial correlations of varying lattice distance; the assumption is that the full system will have finite spatial correlations and thus the behavior of the models within the hierarchy will approach that of the full system. We provide evidence of this convergence in the context of one- and two-dimensional numerical examples. Lower levels within the hierarchy that consider shorter spatial correlations are shown to be up to three orders of magnitude faster than traditional kinetic Monte Carlo methods (KMC) for one-dimensional systems, while predicting similar system dynamics and steady states as KMC methods. We then test the hierarchy on a two-dimensional model for the oxidation of CO on RuO2(110), showing that low-order truncations of the hierarchy efficiently capture the essential system dynamics. By considering sequences of models in the hierarchy that account for longer spatial correlations, successive model predictions may be used to establish empirical approximation of error estimates. The hierarchy may be thought of as a class of generalized phenomenological kinetic models since each element of the hierarchy approximates the master equation and the lowest level in the hierarchy is identical to a simple existing phenomenological kinetic models.

A novel hierarchy of differential—integral equations and their generalized bi-Hamiltonian structures

International Nuclear Information System (INIS)

Zhai Yun-Yun; Geng Xian-Guo; He Guo-Liang

2014-01-01

With the aid of the zero-curvature equation, a novel integrable hierarchy of nonlinear evolution equations associated with a 3 × 3 matrix spectral problem is proposed. By using the trace identity, the bi-Hamiltonian structures of the hierarchy are established with two skew-symmetric operators. Based on two linear spectral problems, we obtain the infinite many conservation laws of the first member in the hierarchy

On the huge Lie superalgebra of pseudo superdifferential operators and super KP-hierarchies

International Nuclear Information System (INIS)

Sedra, M.B.

1995-08-01

Lie superalgebraic methods are used to establish a connection between the huge Lie superalgebra Ξ of super (pseudo) differential operators and various super KP-hierarchies. We show in particular that Ξ splits into 5 = 2 x 2 + 1 graded algebras expected to correspond to five classes of super KP-hierarchies generalizing the well-known Manin-Radul and Figueroa O'Farrill-Ramos supersymmetric KP-hierarchies. (author). 10 refs

Stage-dependent hierarchy of criteria in multiobjective multistage decision processes

Directory of Open Access Journals (Sweden)

Tadeusz Trzaskalik

2017-01-01

Full Text Available This paper will consider a multiobjective, multistage discrete dynamic process with a changeable, state-dependent hierarchy of stage criteria determined by the decision maker. The goal of this paper is to answer the question of how to control a multistage process while taking into account both the tendency to achieve multiobjective optimization of the entire process and the time-varying hierarchy of stage criteria. We consider in detail possible situations, where the hierarchy of stage criteria changes over time in individual stages and is stage dependent. We present an interactive proposal to solving the problem, where the decision maker actively participates in finding the final realization of the process. The algorithm proposed is illustrated using a numerical example.

Office of Geologic Repositories issues hierarchy for a mined geologic disposal system

International Nuclear Information System (INIS)

1987-08-01

The Nuclear Regulatory Commission (NRC) has indicated that the identification of the issues that must be resolved to complete licensing assessments of site and design suitability is an important step in the licensing process. The issues hierarchy developed by the Office of Geologic Repositories (OGR) for the mined geologic disposal system (MGDS) are based on the issues-hierarchy concept presented in the Mission Plan. Specific questions are encompassed by the general issue statements in the OGR issues hierarchy. The OGR issues hierarchy is limited to the issues related to the siting and licensing requirements of applicable federal regulations and does not address the requirements of other regulations, functional or operating requirements for the MGDS, or requirements for the integration and the design/operational efficiency of the MGDS. 4 figs

KdV hierarchy via Abelian coverings and operator identities

OpenAIRE

Eichinger, Benjamin; VandenBoom, Tom; Yuditskii, Peter

2018-01-01

We establish precise spectral criteria for potential functions $V$ of reflectionless Schr\\"odinger operators $L_V = -\\partial_x^2 + V$ to admit solutions to the Korteweg de-Vries (KdV) hierarchy with $V$ as an initial value. More generally, our methods extend the classical study of algebro-geometric solutions for the KdV hierarchy to noncompact Riemann surfaces by defining generalized Abelian integrals and analogues of the Baker-Akhiezer function on infinitely connected domains with a uniform...

The Development of Hierarchy of Effects Model in Advertising

OpenAIRE

Bambang Sukma Wijaya

2012-01-01

This paper aims to review the hierarchy of effects models in adverti-sing, especially the well-known model, AIDA (Attention, Interest, De-sire, and Action). Since its introduction by Lewis (1900) and generally attributed in the marketing and advertising literature by Strong (1925), the concept of AIDA’s hierarchy of effects model has been used by many researchers, both academicians and practitioners. The model is used to measure the effect of an advertisement. However, the deve-lopment of inf...

Bibliometric Evidence for a Hierarchy of the Sciences.

Science.gov (United States)

Fanelli, Daniele; Glänzel, Wolfgang

2013-01-01

The hypothesis of a Hierarchy of the Sciences, first formulated in the 19(th) century, predicts that, moving from simple and general phenomena (e.g. particle dynamics) to complex and particular (e.g. human behaviour), researchers lose ability to reach theoretical and methodological consensus. This hypothesis places each field of research along a continuum of complexity and "softness", with profound implications for our understanding of scientific knowledge. Today, however, the idea is still unproven and philosophically overlooked, too often confused with simplistic dichotomies that contrast natural and social sciences, or science and the humanities. Empirical tests of the hypothesis have usually compared few fields and this, combined with other limitations, makes their results contradictory and inconclusive. We verified whether discipline characteristics reflect a hierarchy, a dichotomy or neither, by sampling nearly 29,000 papers published contemporaneously in 12 disciplines and measuring a set of parameters hypothesised to reflect theoretical and methodological consensus. The biological sciences had in most cases intermediate values between the physical and the social, with bio-molecular disciplines appearing harder than zoology, botany or ecology. In multivariable analyses, most of these parameters were independent predictors of the hierarchy, even when mathematics and the humanities were included. These results support a "gradualist" view of scientific knowledge, suggesting that the Hierarchy of the Sciences provides the best rational framework to understand disciplines' diversity. A deeper grasp of the relationship between subject matter's complexity and consensus could have profound implications for how we interpret, publish, popularize and administer scientific research.

Office of Geologic Respositories issues hierarchy for a Mined Geologic Disposal System (OGR/B-10)

International Nuclear Information System (INIS)

1986-09-01

The Office of Geologic Repositories (OGR) has adopted an issues hierarchy for use by all Project Offices. The issues hierarchy provides a framework for representing issues related to regulatory requirements for siting and licensing a mined geologic disposal system (MGDS) and for describing the work that needs to be completed during site characterization to resolve those issues. The issues in the issues hierarchy are defined as the questions relating to the performance of the MGDS that must be resolved to demonstrate compliance with the applicable federal regulations (including 10 CFR Part 60, 10 CFR Part 960, 40 CFR Part 191, and 10 CFR Part 20). The issues hierarchy is structured around four broad areas of regulatory concern related to the requirements for siting and licensing an MGDS (postclosure performance, preclosure radiological safety, non-radiological environmental impacts, and feasibility and cost of MGDS development), and provides the framework for definition of the information needed to satisfy the applicable regulatory requirements in each of these areas. The purpose of this document is to present the issues hierarchy, describe the rationale used to develop the hierarchy, and describe how the issues hierarchy is used in program planning. Section 2 presents the overall rationale for the issues hierarchy, and explains the structure and organization of the hierarchy. Section 3 presents the issues hierarchy itself and Section 4 describes the basis for the development of individual issues. Section 5 provides a correlation between the issues and the applicable federal regulations being addressed. Section 6 describes how the issues drive development of plans in support of siting and licensing requirements through use of an issue resolution strategy that includes performance allocation

A unified construction for the algebro-geometric quasiperiodic solutions of the Lotka-Volterra and relativistic Lotka-Volterra hierarchy

Science.gov (United States)

Zhao, Peng; Fan, Engui

2015-04-01

In this paper, a new type of integrable differential-difference hierarchy, namely, the generalized relativistic Lotka-Volterra (GRLV) hierarchy, is introduced. This hierarchy is closely related to Lotka-Volterra lattice and relativistic Lotka-Volterra lattice, which allows us to provide a unified and effective way to obtain some exact solutions for both the Lotka-Volterra hierarchy and the relativistic Lotka-Volterra hierarchy. In particular, we shall construct algebro-geometric quasiperiodic solutions for the LV hierarchy and the RLV hierarchy in a unified manner on the basis of the finite gap integration theory.

Urinary Biomarkers KIM-1 and NGAL for Detection of Chronic Kidney Disease of Uncertain Etiology (CKDu) among Agricultural Communities in Sri Lanka

Science.gov (United States)

Mohammed Abdul, Khaja Shameem; Eakanayake, Eakanayake M. D. V.; Jayasinghe, Sudheera Sammanthi; Jayasumana, Channa; Asanthi, Hewa Bandulage; Perera, Hettiarachigae S. D.; Chaminda, Gamage G. Tushara; Chandana, Ediriweera P. S.; Siribaddana, Sisira H.

2016-01-01

Chronic Kidney Disease of uncertain etiology (CKDu) is an emerging epidemic among farming communities in rural Sri Lanka. Victims do not exhibit common causative factors, however, histopathological studies revealed that CKDu is a tubulointerstitial disease. Urine albumin or albumin-creatinine ratio is still being used as a traditional diagnostic tool to identify CKDu, but accuracy and prevalence data generated are questionable. Urinary biomarkers have been used in similar nephropathy and are widely recognised for their sensitivity, specificity and accuracy in determining CKDu and early renal injury. However, these biomarkers have never been used in diagnosing CKDu in Sri Lanka. Male farmers (n = 1734) were recruited from 4 regions in Sri Lanka i.e. Matara and Nuwara Eliya (farming locations with no CKDu prevalence) and two CKDu emerging locations from Hambantota District in Southern Sri Lanka; Angunakolapelessa (EL1) and Bandagiriya (EL2). Albuminuria (ACR ≥ 30mg/g); serum creatinine based estimation of glomerular filtration rate (eGFR); creatinine normalized urinary kidney injury molecule (KIM-1) and neutrophil gelatinase-associated lipocalin (NGAL) were measured. Fourteen new CKDu cases (18%) from EL1 and nine CKDu cases (9%) from EL2 were recognized for the first time from EL1, EL2 locations, which were previously considered as non-endemic of the disease and associated with persistent albuminuria (ACR ≥ 30mg/g Cr). No CKDu cases were identified in non-endemic study locations in Matara (CM) and Nuwara Eliya (CN). Analysis of urinary biomarkers showed urinary KIM-1 and NGAL were significantly higher in new CKDu cases in EL1 and EL2. However, we also reported significantly higher KIM-1 and NGAL in apparently healthy farmers in EL 1 and EL 2 with comparison to both control groups. These observations may indicate possible early renal damage in absence of persistent albuminuria and potential capabilities of urinary KIM-1 and NGAL in early detection of renal injury

Urinary Biomarkers KIM-1 and NGAL for Detection of Chronic Kidney Disease of Uncertain Etiology (CKDu among Agricultural Communities in Sri Lanka.

Directory of Open Access Journals (Sweden)

Pallagae Mangala C S De Silva

2016-09-01

Full Text Available Chronic Kidney Disease of uncertain etiology (CKDu is an emerging epidemic among farming communities in rural Sri Lanka. Victims do not exhibit common causative factors, however, histopathological studies revealed that CKDu is a tubulointerstitial disease. Urine albumin or albumin-creatinine ratio is still being used as a traditional diagnostic tool to identify CKDu, but accuracy and prevalence data generated are questionable. Urinary biomarkers have been used in similar nephropathy and are widely recognised for their sensitivity, specificity and accuracy in determining CKDu and early renal injury. However, these biomarkers have never been used in diagnosing CKDu in Sri Lanka. Male farmers (n = 1734 were recruited from 4 regions in Sri Lanka i.e. Matara and Nuwara Eliya (farming locations with no CKDu prevalence and two CKDu emerging locations from Hambantota District in Southern Sri Lanka; Angunakolapelessa (EL1 and Bandagiriya (EL2. Albuminuria (ACR ≥ 30mg/g; serum creatinine based estimation of glomerular filtration rate (eGFR; creatinine normalized urinary kidney injury molecule (KIM-1 and neutrophil gelatinase-associated lipocalin (NGAL were measured. Fourteen new CKDu cases (18% from EL1 and nine CKDu cases (9% from EL2 were recognized for the first time from EL1, EL2 locations, which were previously considered as non-endemic of the disease and associated with persistent albuminuria (ACR ≥ 30mg/g Cr. No CKDu cases were identified in non-endemic study locations in Matara (CM and Nuwara Eliya (CN. Analysis of urinary biomarkers showed urinary KIM-1 and NGAL were significantly higher in new CKDu cases in EL1 and EL2. However, we also reported significantly higher KIM-1 and NGAL in apparently healthy farmers in EL 1 and EL 2 with comparison to both control groups. These observations may indicate possible early renal damage in absence of persistent albuminuria and potential capabilities of urinary KIM-1 and NGAL in early detection of renal

Urinary Biomarkers KIM-1 and NGAL for Detection of Chronic Kidney Disease of Uncertain Etiology (CKDu) among Agricultural Communities in Sri Lanka.

Science.gov (United States)

De Silva, Pallagae Mangala C S; Mohammed Abdul, Khaja Shameem; Eakanayake, Eakanayake M D V; Jayasinghe, Sudheera Sammanthi; Jayasumana, Channa; Asanthi, Hewa Bandulage; Perera, Hettiarachigae S D; Chaminda, Gamage G Tushara; Chandana, Ediriweera P S; Siribaddana, Sisira H

2016-09-01

Chronic Kidney Disease of uncertain etiology (CKDu) is an emerging epidemic among farming communities in rural Sri Lanka. Victims do not exhibit common causative factors, however, histopathological studies revealed that CKDu is a tubulointerstitial disease. Urine albumin or albumin-creatinine ratio is still being used as a traditional diagnostic tool to identify CKDu, but accuracy and prevalence data generated are questionable. Urinary biomarkers have been used in similar nephropathy and are widely recognised for their sensitivity, specificity and accuracy in determining CKDu and early renal injury. However, these biomarkers have never been used in diagnosing CKDu in Sri Lanka. Male farmers (n = 1734) were recruited from 4 regions in Sri Lanka i.e. Matara and Nuwara Eliya (farming locations with no CKDu prevalence) and two CKDu emerging locations from Hambantota District in Southern Sri Lanka; Angunakolapelessa (EL1) and Bandagiriya (EL2). Albuminuria (ACR ≥ 30mg/g); serum creatinine based estimation of glomerular filtration rate (eGFR); creatinine normalized urinary kidney injury molecule (KIM-1) and neutrophil gelatinase-associated lipocalin (NGAL) were measured. Fourteen new CKDu cases (18%) from EL1 and nine CKDu cases (9%) from EL2 were recognized for the first time from EL1, EL2 locations, which were previously considered as non-endemic of the disease and associated with persistent albuminuria (ACR ≥ 30mg/g Cr). No CKDu cases were identified in non-endemic study locations in Matara (CM) and Nuwara Eliya (CN). Analysis of urinary biomarkers showed urinary KIM-1 and NGAL were significantly higher in new CKDu cases in EL1 and EL2. However, we also reported significantly higher KIM-1 and NGAL in apparently healthy farmers in EL 1 and EL 2 with comparison to both control groups. These observations may indicate possible early renal damage in absence of persistent albuminuria and potential capabilities of urinary KIM-1 and NGAL in early detection of renal injury

The discrete symmetry of the N=2 supersymmetric modified NLS hierarchy

International Nuclear Information System (INIS)

Sorin, A.

1996-01-01

A few new N=2 superintegrable mappings in the (1|2) superspace are proposed and their origin is analyzed. Using one of them, acting like the discrete symmetry transformation of the N=2 supersymmetric modified NLS hierarchy, the recursion operator and Hamiltonian structures of the hierarchy are constructed

Introductory Statement by Won-Soo Kim [International Conference on Nuclear Security: Commitments and Actions, Vienna (Austria), 5-9 December 2016

International Nuclear Information System (INIS)

Kim, Won-Soo

2017-01-01

We need to treat WMD risks and threats holistically. Lessons learned in one area can be emulated in another. The IAEA has learned valuable lessons through its own emergency management work and partnership with other UN agencies, including through the UN Counter-Terrorism Implementation Task Force. These lessons could be beneficial in developing response mechanisms for biological incidents.

Transitivity performance, relational hierarchy knowledge and awareness: results of an instructional framing manipulation.

Science.gov (United States)

Kumaran, Dharshan; Ludwig, Hans

2013-12-01

The transitive inference (TI) paradigm has been widely used to examine the role of the hippocampus in generalization. Here we consider a surprising feature of experimental findings in this task: the relatively poor transitivity performance and levels of hierarchy knowledge achieved by adult human subjects. We focused on the influence of the task instructions on participants' subsequent performance--a single-word framing manipulation which either specified the relation between items as transitive (i.e., OLD-FRAME: choose which item is "older") or left it ambiguous (i.e., NO-FRAME: choose which item is "correct"). We show a marked but highly specific effect of manipulating prior knowledge through instruction: transitivity performance and levels of relational hierarchy knowledge were enhanced, but premise performance unchanged. Further, we show that hierarchy recall accuracy, but not conventional awareness scores, was a significant predictor of inferential performance across the entire group of participants. The current study has four main implications: first, our findings establish the importance of the task instructions, and prior knowledge, in the TI paradigm--suggesting that they influence the size of the overall hypothesis space (e.g., to favor a linear hierarchical structure over other possibilities in the OLD-FRAME). Second, the dissociable effects of the instructional frame on premise and inference performance provide evidence for the operation of distinct underlying mechanisms (i.e., an associative mechanism vs. relational hierarchy knowledge). Third, our findings suggest that a detailed measurement of hierarchy recall accuracy may be a more sensitive index of relational hierarchy knowledge, than conventional awareness score--and should be used in future studies investigating links between awareness and inferential performance. Finally, our study motivates an experimental setting that ensures robust hierarchy learning across participants

Scalable quality assurance for large SNOMED CT hierarchies using subject-based subtaxonomies.

Science.gov (United States)

Ochs, Christopher; Geller, James; Perl, Yehoshua; Chen, Yan; Xu, Junchuan; Min, Hua; Case, James T; Wei, Zhi

2015-05-01

Standards terminologies may be large and complex, making their quality assurance challenging. Some terminology quality assurance (TQA) methodologies are based on abstraction networks (AbNs), compact terminology summaries. We have tested AbNs and the performance of related TQA methodologies on small terminology hierarchies. However, some standards terminologies, for example, SNOMED, are composed of very large hierarchies. Scaling AbN TQA techniques to such hierarchies poses a significant challenge. We present a scalable subject-based approach for AbN TQA. An innovative technique is presented for scaling TQA by creating a new kind of subject-based AbN called a subtaxonomy for large hierarchies. New hypotheses about concentrations of erroneous concepts within the AbN are introduced to guide scalable TQA. We test the TQA methodology for a subject-based subtaxonomy for the Bleeding subhierarchy in SNOMED's large Clinical finding hierarchy. To test the error concentration hypotheses, three domain experts reviewed a sample of 300 concepts. A consensus-based evaluation identified 87 erroneous concepts. The subtaxonomy-based TQA methodology was shown to uncover statistically significantly more erroneous concepts when compared to a control sample. The scalability of TQA methodologies is a challenge for large standards systems like SNOMED. We demonstrated innovative subject-based TQA techniques by identifying groups of concepts with a higher likelihood of having errors within the subtaxonomy. Scalability is achieved by reviewing a large hierarchy by subject. An innovative methodology for scaling the derivation of AbNs and a TQA methodology was shown to perform successfully for the largest hierarchy of SNOMED. © The Author 2014. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

The significance of 'hierarchy' in a research project on adoption and adaptation.

Science.gov (United States)

Mander, R

1999-06-01

In the course of phenomenological research project focusing on the midwife's care of the mother who relinquishes her baby for adoption, hierarchy emerged repeatedly as a significant theme. This concept manifested itself both methodologically as well as thematically. In methodological terms, hierarchy first became apparent during the planning phase in the selection of the research design: at this point it took the form of the distinction between quantitative and qualitative research design. In the course of applying for research access the same attitudes re-emerged in the gatekeepers' responses to the research design which had been chose. Later, during the field work, hierarchy appeared in the course of the interviews, in the form of the unequal balance of power between the interviewer and the informant. Specific tactics were required to overcome the likelihood of hierarchy affecting the data at this stage. Eventually this concept was raised by the informants, who included both relinquishing mothers an midwives, and became a major theme. The informants' use of hierarchy to explain the unselfishness of relinquishment proved to be one of a number of strategies which facilitated coping either with the experience of relinquishment or with caring for a women going through that experience. The conclusion which emerges is that hierarchy features in many aspects of life. While it may be beneficial when applied to certain situations to facilitate coping, in other circumstances it may be less than positive.

Void hierarchy and cosmic structure

International Nuclear Information System (INIS)

Weygaert, Rien van de; Ravi Sheth

2004-01-01

Within the context of hierarchical scenarios of gravitational structure formation we describe how an evolving hierarchy of voids evolves on the basis of two processes, the void-in-void process and the void-in-cloud process. The related analytical formulation in terms of a two-barrier excursion problem leads to a self-similarly evolving peaked void size distribution

Classification hierarchies for product data modelling

NARCIS (Netherlands)

Pels, H.J.

2006-01-01

Abstraction is an essential element in data modelling that appears mainly in one of the following forms: generalisation, classification or aggregation. In the design of complex products classification hierarchies can be found product families that are viewed as classes of product types, while

Determining neutrino mass hierarchy from electron disappearance at a low energy neutrino factory

International Nuclear Information System (INIS)

Raut, Sushant K.

2013-01-01

Reactor neutrino experiments have recently measured the value of θ 13 , to be non-zero and moderately large. This makes the determination of the neutrino mass hierarchy possible. However, our lack of knowledge of δ CP results in a parameter degeneracy, which makes this task difficult. The electron neutrino disappearance probability does not depend on δ CP . Therefore, in principle, it is possible to determine the hierarchy independently of δ CP using this channel. Previous studies of neutrino factories have not considered this channel, because the effect of systematics in electron disappearance is substantial. However, we show that for the moderately large value of θ 13 measured, hierarchy determination is possible in spite of systematic effects. We consider a low energy neutrino factory (LENF) setup with a totally active scintillator detector (TASD) with charge-identification. We optimize the setup in muon energy and baseline, for different allowed values of θ 13 and runtime. We find that a LENF with baseline of around 1300 km and muon energy around 3-4 GeV is well suited for hierarchy determination. For the RENO best-fit value of θ 13 , this setup can determine the hierarchy at 5ω, for all values of δ CP and for both hierarchies. (author)

Comorbidities in obstructive lung disease in Korea: data from the fourth and fifth Korean National Health and Nutrition Examination Survey

Directory of Open Access Journals (Sweden)

Park HJ

2015-08-01

Full Text Available Hee Jin Park, Ah Young Leem, Sang Hoon Lee, Ju Han Song, Moo Suk Park, Young Sam Kim, Se Kyu Kim, Joon Chang, Kyung Soo Chung Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Severance Hospital, Institute of Chest Disease, Yonsei University College of Medicine, Seoul, South Korea Background: Comorbidities can occur frequently in patients with chronic obstructive pulmonary disease (COPD and can influence mortality and morbidity independently. It is increasingly recognized that many patients with COPD have comorbidities that have a major impact on their quality of life and survival. Therefore, we investigated the prevalence of comorbidities in Korean COPD populations. Methods: We used data obtained in the 6 years of the fourth and fifth Korean National Health and Nutrition Examination Survey (KNHANES IV and V. Among 50,405 subjects, 16,151 subjects aged ≥40 years who performed spirometry adequately were included in this study. Airway obstruction was defined as forced expiratory volume in 1 second/forced vital capacity <0.7, and the Global Initiative For Chronic Obstructive Lung Disease stage was used to evaluate the severity of airway obstruction. Statistical analyses were performed using SAS 9.2. Results: Among the 16,151 subjects (43.2% male, 56.8% female; mean age: 57.1 years for men and 57.2 years for women, 13.1% had obstructive lung function; 11.3%, restrictive lung function; and 75.6%, normal lung function. Among individuals with obstructive lung function, 45.3%, 49.4%, and 5.3% had mild, moderate, and severe and very severe airflow limitation. The prevalence of hypertension, diabetes mellitus (DM, underweight, and hypertriglyceridemia was higher in the obstructive lung function group than in the normal lung function group (49.6% vs 35.2%; 16.8% vs 10.5%; 3.3% vs 1.3%; 19.7% vs 17.0%. According to the severity of airway obstruction, hypertension and underweight were more common as severity increased

Organising evidence for environmental management decisions: a '4S' hierarchy.

Science.gov (United States)

Dicks, Lynn V; Walsh, Jessica C; Sutherland, William J

2014-11-01

Making decisions informed by the best-available science is an objective for many organisations managing the environment or natural resources. Yet, available science is still not widely used in environmental policy and practice. We describe a '4S' hierarchy for organising relevant science to inform decisions. This hierarchy has already revolutionised clinical practice. It is beginning to emerge for environmental management, although all four levels need substantial development before environmental decision-makers can reliably and efficiently find the evidence they need. We expose common bypass routes that currently lead to poor or biased representation of scientific knowledge. We argue that the least developed level of the hierarchy is that closest to decision-makers, placing synthesised scientific knowledge into environmental decision support systems. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

Effects of neutrino oscillation on supernova neutrino: inverted mass hierarchy

International Nuclear Information System (INIS)

Takahashi, Keitaro; Sato, Katsuhiko

2003-01-01

We study the effects of neutrino oscillation on supernova neutrino in the case of the inverted mass hierarchy (m 3 1 2 ). This is an extended study of our previous study where all analyses are performed with normal mass hierarchy (m 1 2 3 ). Numerical analysis using a realistic supernova and presupernova model allow us to discuss quantitatively a possibility to probe neutrino oscillation parameters. We show that we can break partly the degeneracy of the solar neutrino problem (LMA or SMA) and probe the magnitude of θ 13 to some extent by the ratios of high-energy events and low-energy events at SuperKamiokande and SNO and the presence of the Earth effects. Further, if the magnitude of θ 13 is known roughly, we can identify the mass hierarchy

On a non-local gas dynamics like integrable hierarchy

International Nuclear Information System (INIS)

Brunelli, Jose Carlos; Das, Ashok

2004-01-01

We study a new hierarchy of equations derived from the system of isentropic gas dynamics equations where the pressure is a non-local function of the density. We show that the hierarchy of equations is integrable. We construct the two compatible Hamiltonian structures and show that the first structure has three distinct Casimirs while the second has one. The existence of Casimirs allows us to extend the flows to local ones. We construct an infinite series of commuting local Hamiltonians as well as three infinite series (related to the three Casimirs) of non-local charges. We discuss the zero curvature formulation of the system where we obtain a simple expression for the non-local conserved charges, which also clarifies the existence of the three series from a Lie algebraic point of view. We point out that the non-local hierarchy of Hunter-Zheng equations can be obtained from our non-local flows when the dynamical variables are properly constrained. (author)

A reflection on Russell's ramified types and Kripke's hierarchy of truths

NARCIS (Netherlands)

Kamareddine, F.; Laan, T.D.L.

1996-01-01

Both in Kripke's Theory of Truth KTT [8] and Russell's Ramified Type Theory RTT [16, 9] we are confronted with some hierarchy. In RTT, we have a double hierarchy of orders and types. That is, the class of propositions is divided into different orders where a propositional function can only depend on

'If you are good, I get better': the role of social hierarchy in perceptual decision-making.

Science.gov (United States)

Santamaría-García, Hernando; Pannunzi, Mario; Ayneto, Alba; Deco, Gustavo; Sebastián-Gallés, Nuria

2014-10-01

So far, it was unclear if social hierarchy could influence sensory or perceptual cognitive processes. We evaluated the effects of social hierarchy on these processes using a basic visual perceptual decision task. We constructed a social hierarchy where participants performed the perceptual task separately with two covertly simulated players (superior, inferior). Participants were faster (better) when performing the discrimination task with the superior player. We studied the time course when social hierarchy was processed using event-related potentials and observed hierarchical effects even in early stages of sensory-perceptual processing, suggesting early top-down modulation by social hierarchy. Moreover, in a parallel analysis, we fitted a drift-diffusion model (DDM) to the results to evaluate the decision making process of this perceptual task in the context of a social hierarchy. Consistently, the DDM pointed to nondecision time (probably perceptual encoding) as the principal period influenced by social hierarchy. © The Author (2013). Published by Oxford University Press. For Permissions, please email: journals.permissions@oup.com.

Agile and Resilient Hierarchies for Defense Departments: Lofty Ideal or an Actionable Proposal

National Research Council Canada - National Science Library

Desouza, Kevin C

2006-01-01

... only consideration. Completely agile structures may lose the benefits bestowed by hierarchies. Rather the Defense Department should work towards agile and resilient hierarchies that can recover quickly following setbacks.

Magnetic flux creep in HTSC and Anderson-Kim theory

International Nuclear Information System (INIS)

Lykov, A.N.

2014-01-01

The theoretical and experimental data on flux creep in high-temperature superconductors (HTSC) were analyzed in the review paper. On the one hand, the main attention is paid to the most striking experimental results which have had a significant influence on the investigations of flux creep in HTSC. On the other hand, the analysis of theoretical studies is concentrated on the works, which explain the features of flux creep on the basis of the Anderson-Kim (AK) theory modifications, and received previously unsufficient attention. However, it turned out that the modified AK theory could explain a lot of features of flux creep in HTSC: the scaling behaviour of current-voltage curves of HTSC, the finite rate of flux creep at ultra low temperatures, the logarithmic dependence of effective pinning potential as a function of transport current and its decrease with temperature. The harmonic potential field which is used in this approach makes it possible to solve accurately the both problems: viscous vortex motion and flux creep in this field. Moreover the distribution of pinning potential and the interaction of vortices with each other are taken into account in the approach. Thus, the modification of the AK theory consists, essentially, in its detailed elaboration and approaching to real situations in superconductors

A remark on Kac-Wakimoto hierarchies of D-type

International Nuclear Information System (INIS)

Wu Chaoxzhong

2010-01-01

For the Kac-Wakimoto hierarchy constructed from the principal vertex operator realization of the basic representation of the affine Lie algebra D (1) n , we compute the coefficients of the corresponding Hirota bilinear equations, and verify the coincidence of these bilinear equations with the ones that are satisfied by Givental's total descendant potential of the D n singularity, as conjectured by Givental and Milanov (2005 Simple singularities and integrable hierarchies The Breadth of Symplectic and Poisson Geometry (Prog. Math. vol 232) (Boston: Birkhaeuser) pp 173-201).

Quasiclassical deformation in KP hierarchy and Benney's long wave equations

International Nuclear Information System (INIS)

Kolokol'tsov, V.N.; Lebedev, D.R.

1987-01-01

In the paper by means of the formal variant of Zakharov-Shabat ''dressing'' method various formulas are obtained for the generating functions of the conservation laws of Kadomtsev-Petvias hierarchy which turn into analogous formulas for Benney hierarchy in the quasiclassical limit. The generating fucntion of the conservation laws of Miura type is constructed for higher Benney equations and the simple proof of the related identities is given

Determining the neutrino mass hierarchy with cosmology

International Nuclear Information System (INIS)

De Bernardis, Francesco; Kitching, Thomas D.; Heavens, Alan; Melchiorri, Alessandro

2009-01-01

The combination of current large-scale structure and cosmic microwave background anisotropies data can place strong constraints on the sum of the neutrino masses. Here we show that future cosmic shear experiments, in combination with cosmic microwave background constraints, can provide the statistical accuracy required to answer questions about differences in the mass of individual neutrino species. Allowing for the possibility that masses are nondegenerate we combine Fisher matrix forecasts for a weak lensing survey like Euclid with those for the forthcoming Planck experiment. Under the assumption that neutrino mass splitting is described by a normal hierarchy we find that the combination Planck and Euclid will possibly reach enough sensitivity to put a constraint on the mass of a single species. Using a Bayesian evidence calculation we find that such future experiments could provide strong evidence for either a normal or an inverted neutrino hierarchy. Finally we show that if a particular neutrino hierarchy is assumed then this could bias cosmological parameter constraints, for example, the dark energy equation of state parameter, by > or approx. 1σ, and the sum of masses by 2.3σ. We finally discuss the impact of uncertainties on the theoretical modeling of nonlinearities. The results presented in this analysis are obtained under an approximation to the nonlinear power spectrum. This significant source of uncertainty needs to be addressed in future work.

A Liouville integrable hierarchy, symmetry constraint, new finite-dimensional integrable systems, involutive solution and expanding integrable models

International Nuclear Information System (INIS)

Sun Yepeng; Chen Dengyuan

2006-01-01

A new spectral problem and the associated integrable hierarchy of nonlinear evolution equations are presented in this paper. It is shown that the hierarchy is completely integrable in the Liouville sense and possesses bi-Hamiltonian structure. An explicit symmetry constraint is proposed for the Lax pairs and the adjoint Lax pairs of the hierarchy. Moreover, the corresponding Lax pairs and adjoint Lax pairs are nonlinearized into a hierarchy of commutative, new finite-dimensional completely integrable Hamiltonian systems in the Liouville sense. Further, an involutive representation of solution of each equation in the hierarchy is given. Finally, expanding integrable models of the hierarchy are constructed by using a new Loop algebra

The integrity of the social hierarchy in mice following administration of psychotropic drugs.

OpenAIRE

Poshivalov, V. P.

1980-01-01

1 Mice in small groups develop a despotic type of social hierarchy, a feature of which is to resist alteration through the medium of psychotropic drugs. This makes a rapid pharmacologically induced change in the social hierarchy impossible. 2 Patrolling the territory and a certain level of social interaction are both critical factors in maintaining the phenomenon of inertia in the social hierarchy. Psychotropic drugs (diazepam, droperidol and mescaline) altered both these factors to a varying...

Reduction of proteinuria in adriamycin-induced nephropathy is associated with reduction of renal kidney injury molecule (Kim-1) over time

NARCIS (Netherlands)

Kramer, Andrea B.; van Timmeren, Mirjan M.; Schuurs, Theo A.; Vaidya, Vishal S.; Bonventre, Joseph V.; van Goor, Harry; Navis, Gerjan

Kramer AB, van Timmeren MM, Schuurs TA, Vaidya VS, Bonventre JV, van Goor H, Navis G. Reduction of proteinuria in adriamycin-induced nephropathy is associated with reduction of renal kidney injury molecule (Kim-1) over time. Am J Physiol Renal Physiol 296: F1136-F1145, 2009. First published February

The influence of social hierarchy on primate health.

Science.gov (United States)

Sapolsky, Robert M

2005-04-29

Dominance hierarchies occur in numerous social species, and rank within them can greatly influence the quality of life of an animal. In this review, I consider how rank can also influence physiology and health. I first consider whether it is high- or low-ranking animals that are most stressed in a dominance hierarchy; this turns out to vary as a function of the social organization in different species and populations. I then review how the stressful characteristics of social rank have adverse adrenocortical, cardiovascular, reproductive, immunological, and neurobiological consequences. Finally, I consider how these findings apply to the human realm of health, disease, and socioeconomic status.

Goal hierarchy: Improving asset data quality by improving motivation

Energy Technology Data Exchange (ETDEWEB)

Unsworth, Kerrie, E-mail: Kerrie.unsworth@uwa.edu.au [UWA Business School, University of Western Australia, Crawley, WA 6009 (Australia); Adriasola, Elisa; Johnston-Billings, Amber; Dmitrieva, Alina [UWA Business School, University of Western Australia, Crawley, WA 6009 (Australia); Hodkiewicz, Melinda [School of Mechanical Engineering, University of Western Australia, Crawley, WA 6009 (Australia)

2011-11-15

Many have recognized the need for high quality data on assets and the problems in obtaining them, particularly when there is a need for human observation and manual recording. Yet very few have looked at the role of the data collectors themselves in the data quality process. This paper argues that there are benefits to more fully understanding the psychological factors that lay behind data collection and we use goal hierarchy theory to understand these factors. Given the myriad of potential reasons for poor-quality data it has previously proven difficult to identify and successfully deploy employee-driven interventions; however, the goal hierarchy approach looks at all of the goals that an individual has in their life and the connections between them. For instance, does collecting data relate to whether or not they get a promotion? Stay safe? Get a new job? and so on. By eliciting these goals and their connections we can identify commonalities across different groups, sites or organizations that can influence the quality of data collection. Thus, rather than assuming what the data collectors want, a goal hierarchy approach determines that empirically. Practically, this supports the development of customized interventions that will be much more effective and sustainable than previous efforts. - Highlights: > We need to consider psychological aspects of data collectors to improve data quality. > We show how goal hierarchy theory furthers understanding. > Looks at the multiple goals of each individual to determine their behavior.

Goal hierarchy: Improving asset data quality by improving motivation

International Nuclear Information System (INIS)

Unsworth, Kerrie; Adriasola, Elisa; Johnston-Billings, Amber; Dmitrieva, Alina; Hodkiewicz, Melinda

2011-01-01

Many have recognized the need for high quality data on assets and the problems in obtaining them, particularly when there is a need for human observation and manual recording. Yet very few have looked at the role of the data collectors themselves in the data quality process. This paper argues that there are benefits to more fully understanding the psychological factors that lay behind data collection and we use goal hierarchy theory to understand these factors. Given the myriad of potential reasons for poor-quality data it has previously proven difficult to identify and successfully deploy employee-driven interventions; however, the goal hierarchy approach looks at all of the goals that an individual has in their life and the connections between them. For instance, does collecting data relate to whether or not they get a promotion? Stay safe? Get a new job? and so on. By eliciting these goals and their connections we can identify commonalities across different groups, sites or organizations that can influence the quality of data collection. Thus, rather than assuming what the data collectors want, a goal hierarchy approach determines that empirically. Practically, this supports the development of customized interventions that will be much more effective and sustainable than previous efforts. - Highlights: → We need to consider psychological aspects of data collectors to improve data quality. → We show how goal hierarchy theory furthers understanding. → Looks at the multiple goals of each individual to determine their behavior.

Some Evolution Hierarchies Derived from Self-dual Yang-Mills Equations

International Nuclear Information System (INIS)

Zhang Yufeng; Hon, Y.C.

2011-01-01

We develop in this paper a new method to construct two explicit Lie algebras E and F. By using a loop algebra Ē of the Lie algebra E and the reduced self-dual Yang-Mills equations, we obtain an expanding integrable model of the Giachetti-Johnson (GJ) hierarchy whose Hamiltonian structure can also be derived by using the trace identity. This provides a much simpler construction method in comparing with the tedious variational identity approach. Furthermore, the nonlinear integrable coupling of the GJ hierarchy is readily obtained by introducing the Lie algebra g N . As an application, we apply the loop algebra E-tilde of the Lie algebra E to obtain a kind of expanding integrable model of the Kaup-Newell (KN) hierarchy which, consisting of two arbitrary parameters α and β, can be reduced to two nonlinear evolution equations. In addition, we use a loop algebra F of the Lie algebra F to obtain an expanding integrable model of the BT hierarchy whose Hamiltonian structure is the same as using the trace identity. Finally, we deduce five integrable systems in R 3 based on the self-dual Yang-Mills equations, which include Poisson structures, irregular lines, and the reduced equations. (general)

Fuzzy Logic and Arithmetical Hierarchy III

Czech Academy of Sciences Publication Activity Database

Hájek, Petr

2001-01-01

Roč. 68, č. 1 (2001), s. 129-142 ISSN 0039-3215 R&D Projects: GA AV ČR IAA1030004 Institutional research plan: AV0Z1030915 Keywords : fuzzy logic * basic fuzzy logic * Lukasiewicz logic * Godel logic * product logic * arithmetical hierarchy Subject RIV: BA - General Mathematics

Large hierarchies from approximate R symmetries

International Nuclear Information System (INIS)

Kappl, Rolf; Ratz, Michael; Vaudrevange, Patrick K.S.

2008-12-01

We show that hierarchically small vacuum expectation values of the superpotential in supersymmetric theories can be a consequence of an approximate R symmetry. We briefly discuss the role of such small constants in moduli stabilization and understanding the huge hierarchy between the Planck and electroweak scales. (orig.)

New solutions to the hierarchy problem

International Nuclear Information System (INIS)

Burdman, Gustavo

2007-01-01

After summarizing the status of the Standard Model, we focus on the Hierarchy Problem and why we believe this strongly suggests the need for new physics at the TeV scale. We then concentrate on theories with extra dimensions and their possible manifestations at this scale. (author)

A Lax integrable hierarchy, bi-Hamiltonian structure and finite-dimensional Liouville integrable involutive systems

International Nuclear Information System (INIS)

Xia Tiecheng; Chen Xiaohong; Chen Dengyuan

2004-01-01

An eigenvalue problem and the associated new Lax integrable hierarchy of nonlinear evolution equations are presented in this paper. As two reductions, the generalized nonlinear Schroedinger equations and the generalized mKdV equations are obtained. Zero curvature representation and bi-Hamiltonian structure are established for the whole hierarchy based on a pair of Hamiltonian operators (Lenard's operators), and it is shown that the hierarchy of nonlinear evolution equations is integrable in Liouville's sense. Thus the hierarchy of nonlinear evolution equations has infinitely many commuting symmetries and conservation laws. Moreover the eigenvalue problem is nonlinearized as a finite-dimensional completely integrable system under the Bargmann constraint between the potentials and the eigenvalue functions. Finally finite-dimensional Liouville integrable system are found, and the involutive solutions of the hierarchy of equations are given. In particular, the involutive solutions are developed for the system of generalized nonlinear Schroedinger equations

Hierarchy, Violence and Bullying Among Students of Public Middle Schools

Directory of Open Access Journals (Sweden)

José Leon Crochík

Full Text Available Abstract Hierarchies established in schools can lead to violence among students, particularly bullying, and this relationship is investigated in this study. A School Hierarchies Scale and a Peer Perception of Aggression Scale were applied to 274 9th grade students, both sexes, aged 14.08 years (SD = 0.81 old on average, attending four public schools in the state of São Paulo, Brazil. The students more frequently perceived to be popular, were among the best in physical education and/or among the worst in academic subjects were also more frequently perceived to be bullies, while those more frequently perceived to be unpopular and having the worst performance in physical education were also more frequently perceived to be victims. Therefore, teachers should reflect upon the issue and fight school violence that may arise from these hierarchies.

Directions for memory hierarchies and their components: research and development

International Nuclear Information System (INIS)

Smith, A.J.

1978-10-01

The memory hierarchy is usually the largest identifiable part of a computer system and making effective use of it is critical to the operation and use of the system. The levels of such a memory hierarchy are considered and the state of the art and likely directions for both research and development are described. Algorithmic and logical features of the hierarchy not directly associated with specific components are also discussed. Among the problems believed to be the most significant are the following: (a) evaluate the effectiveness of gap filler technology as a level of storage between main memory and disk, and if it proves to be effective, determine how/where it should be used, (b) develop algorithms for the use of mass storage in a large computer system, and (c) determine how cache memories should be implemented in very large, fast multiprocessor systems

New Hamiltonian structure of the fractional C-KdV soliton equation hierarchy

International Nuclear Information System (INIS)

Yu Fajun; Zhang Hongqing

2008-01-01

A generalized Hamiltonian structure of the fractional soliton equation hierarchy is presented by using of differential forms and exterior derivatives of fractional orders. Example of the fractional Hamiltonian system of the C-KdV soliton equation hierarchy is constructed, which is a new Hamiltonian structure

Planning hierarchy, modeling and sdvanced planning dystems

OpenAIRE

Meyr, Herbert Ottmar

2003-01-01

Planning hierarchy, modeling and sdvanced planning dystems / B. Fleischmann, H. Meyr. - In: Supply chain management / ed. by A. G. de Kok ... - Amsterdam u.a. : Elsevier, 2003. - (Handbooks in operations research and management science ; 11)

Hierarchies without symmetries from extra dimensions

International Nuclear Information System (INIS)

Arkani-Hamed, Nima; Schmaltz, Martin

2000-01-01

It is commonly thought that small couplings in a low-energy theory, such as those needed for the fermion mass hierarchy or proton stability, must originate from symmetries in a high-energy theory. We show that this expectation is violated in theories where the standard model fields are confined to a thick wall in extra dimensions, with the fermions ''stuck'' at different points in the wall. Couplings between them are then suppressed due to the exponentially small overlaps of their wave functions. This provides a framework for understanding both the fermion mass hierarchy and proton stability without imposing symmetries, but rather in terms of higher dimensional geography. A model independent prediction of this scenario is non-universal couplings of the standard model fermions to the ''Kaluza-Klein'' excitations of the gauge fields. This allows a measurement of the fermion locations in the extra dimensions at the CERN LHC or NLC if the wall thickness is close to the TeV scale. (c) 2000 The American Physical Society

Hierarchies Without Symmetries from Extra Dimensions

International Nuclear Information System (INIS)

Arkani-Hamed, Nima

1999-01-01

It is commonly thought that small couplings in a low-energy theory, such as those needed for the fermion mass hierarchy or proton stability, must originate from symmetries in a high-energy theory. We show that this expectation is violated in theories where the Standard Model fields are confined to a thick wall in extra dimensions, with the fermions ''stuck'' at different points in the wall. Couplings between them are then suppressed due to the exponentially small overlaps of their wave functions. This provides a framework for understanding both the fermion mass hierarchy and proton stability without imposing symmetries, but rather in terms of higher dimensional geography. A model independent prediction of this scenario is non-universal couplings of the Standard Model fermions to the ''Kaluza-Klein'' excitations of the gauge fields. This allows a measurement of the fermion locations in the extra dimensions at the LHC or NLC if the wall thickness is close to the TeV scale

Green Degree Comprehensive Evaluation of Elevator Based on Fuzzy Analytic Hierarchy Process

Directory of Open Access Journals (Sweden)

Lizhen

2015-01-01

Full Text Available The green design of the elevator has many characteristics which contains many factors and the combination of qualitative and quantitative. In view of the fuzzy problem of evaluation index information, fuzzy analytic hierarchy process and fuzzy comprehensive evaluation model are combined to evaluate the green degree of elevator. In this method, the weights of the indexes are calculated by using the fuzzy analytic hierarchy process and the fuzzy analytic hierarchy process is used to calculate the weights of each level. The feasibility will be defined of using green degree evaluation of elevator system as an example to verify the method.

A Game-Theoretical Winner and Loser Model of Dominance Hierarchy Formation.

Science.gov (United States)

Kura, Klodeta; Broom, Mark; Kandler, Anne

2016-06-01

Many animals spend large parts of their lives in groups. Within such groups, they need to find efficient ways of dividing available resources between them. This is often achieved by means of a dominance hierarchy, which in its most extreme linear form allocates a strict priority order to the individuals. Once a hierarchy is formed, it is often stable over long periods, but the formation of hierarchies among individuals with little or no knowledge of each other can involve aggressive contests. The outcome of such contests can have significant effects on later contests, with previous winners more likely to win (winner effects) and previous losers more likely to lose (loser effects). This scenario has been modelled by a number of authors, in particular by Dugatkin. In his model, individuals engage in aggressive contests if the assessment of their fighting ability relative to their opponent is above a threshold [Formula: see text]. Here we present a model where each individual can choose its own value [Formula: see text]. This enables us to address questions such as how aggressive should individuals be in order to take up one of the first places in the hierarchy? We find that a unique strategy evolves, as opposed to a mixture of strategies. Thus, in any scenario there exists a unique best level of aggression, and individuals should not switch between strategies. We find that for optimal strategy choice, the hierarchy forms quickly, after which there are no mutually aggressive contests.

Feminist Praxis, Critical Theory and Informal Hierarchies

Directory of Open Access Journals (Sweden)

Eva Giraud

2015-05-01

Full Text Available This article draws on my experiences teaching across two undergraduate media modules in a UK research-intensive institution to explore tactics for combatting both institutional and informal hierarchies within university teaching contexts. Building on Sara Motta’s (2012 exploration of implementing critical pedagogic principles at postgraduate level in an elite university context, I discuss additional tactics for combatting these hierarchies in undergraduate settings, which were developed by transferring insights derived from informal workshops led by the University of Nottingham’s Feminism and Teaching network into the classroom. This discussion is framed in relation to the concepts of “cyborg pedagogies” and “political semiotics of articulation,” derived from the work of Donna Haraway, in order to theorize how these tactics can engender productive relationships between radical pedagogies and critical theory.