WorldWideScience

Sample records for hidden platform trials

  1. International Clinical Trials Registry Platform (ICTRP)

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    @@ Introduction The mission of the WHO Intemational Clinical Trials Registry Platform is to ensure that a complete view of research is accessible to all those involved in health care decision making.This will improve research transparency and will ultimately strengthen tha validity and value of the scientific evidence base.The registration of all interventional trials is a scientific, ethical and moral responsibility.

  2. Classification of EEG Single Trial Microstates Using Local Global Graphs and Discrete Hidden Markov Models.

    Science.gov (United States)

    Michalopoulos, Kostas; Zervakis, Michalis; Deiber, Marie-Pierre; Bourbakis, Nikolaos

    2016-09-01

    We present a novel synergistic methodology for the spatio-temporal analysis of single Electroencephalogram (EEG) trials. This new methodology is based on the novel synergy of Local Global Graph (LG graph) to characterize define the structural features of the EEG topography as a global descriptor for robust comparison of dominant topographies (microstates) and Hidden Markov Models (HMM) to model the topographic sequence in a unique way. In particular, the LG graph descriptor defines similarity and distance measures that can be successfully used for the difficult comparison of the extracted LG graphs in the presence of noise. In addition, hidden states represent periods of stationary distribution of topographies that constitute the equivalent of the microstates in the model. The transitions between the different microstates and the formed syntactic patterns can reveal differences in the processing of the input stimulus between different pathologies. We train the HMM model to learn the transitions between the different microstates and express the syntactic patterns that appear in the single trials in a compact and efficient way. We applied this methodology in single trials consisting of normal subjects and patients with Progressive Mild Cognitive Impairment (PMCI) to discriminate these two groups. The classification results show that this approach is capable to efficiently discriminate between control and Progressive MCI single trials. Results indicate that HMMs provide physiologically meaningful results that can be used in the syntactic analysis of Event Related Potentials.

  3. Implementing clinical trials on an international platform: challenges and perspectives.

    Science.gov (United States)

    Minisman, Greg; Bhanushali, Minal; Conwit, Robin; Wolfe, Gil I; Aban, Inmaculada; Kaminski, Henry J; Cutter, Gary

    2012-02-15

    The importance of conducting medical research on a global or international platform cannot be overemphasized in current times. Sponsors are encouraging international clinical trials for a number of reasons. Globally, clinical trials are under increasing pressure to meet patient recruitment goals quickly and efficiently, at times with very limited resources. Conducting clinical trials in multiple countries increases access to potentially eligible study subjects. It is reasonable to believe that international trials will be completed more quickly and efficiently, leading to more rapid advancement in science and conservation of research-specific resources. Rapid advancement in science can reduce the burden of disease, promote health, and extend longevity for all people. In addition, generalizability, one of the major goals of translational medicine, will increase when recruiting patients from multiple countries and multiple ethnicities. Further, improvement of global health may be possible when certain types of clinical trials are conducted in countries that would not otherwise have access to an innovative drug or intervention. Published by Elsevier B.V.

  4. Reducing trial length in force platform posturographic sleep deprivation measurements

    Science.gov (United States)

    Forsman, P.; Hæggström, E.; Wallin, A.

    2007-09-01

    Sleepiness correlates with sleep-related accidents, but convenient tests for sleepiness monitoring are scarce. The posturographic test is a method to assess balance, and this paper describes one phase of the development of a posturographic sleepiness monitoring method. We investigated the relationship between trial length and accuracy of the posturographic time-awake (TA) estimate. Twenty-one healthy adults were kept awake for 32 h and their balance was recorded, 16 times with 30 s trials, as a function of TA. The balance was analysed with regards to fractal dimension, most common sway amplitude and time interval for open-loop stance control. While a 30 s trial allows estimating the TA of individual subjects with better than 5 h accuracy, repeating the analysis using shorter trial lengths showed that 18 s sufficed to achieve the targeted 5 h accuracy. Moreover, it was found that with increasing TA, the posturographic parameters estimated the subjects' TA more accurately.

  5. A WiMAX Payload for High Altitude Platform Experimental Trials

    Directory of Open Access Journals (Sweden)

    Tim C. Tozer

    2008-12-01

    Full Text Available The Swiss-based “StratXX” project during 2006-2007 has been developing a stratospheric lighter-than-air platform for deployment of telecommunications and environmental monitoring services. In support of a first round of experimental trials, a WiMAX communications subsystem, including platform payload and ground stations, has been developed. The communications system design and results of terrestrial pretrials are reported.

  6. Making randomised trials more efficient: report of the first meeting to discuss the Trial Forge platform.

    Science.gov (United States)

    Treweek, Shaun; Altman, Doug G; Bower, Peter; Campbell, Marion; Chalmers, Iain; Cotton, Seonaidh; Craig, Peter; Crosby, David; Davidson, Peter; Devane, Declan; Duley, Lelia; Dunn, Janet; Elbourne, Diana; Farrell, Barbara; Gamble, Carrol; Gillies, Katie; Hood, Kerry; Lang, Trudie; Littleford, Roberta; Loudon, Kirsty; McDonald, Alison; McPherson, Gladys; Nelson, Annmarie; Norrie, John; Ramsay, Craig; Sandercock, Peter; Shanahan, Daniel R; Summerskill, William; Sydes, Matt; Williamson, Paula; Clarke, Mike

    2015-06-05

    Randomised trials are at the heart of evidence-based healthcare, but the methods and infrastructure for conducting these sometimes complex studies are largely evidence free. Trial Forge ( www.trialforge.org ) is an initiative that aims to increase the evidence base for trial decision making and, in doing so, to improve trial efficiency.This paper summarises a one-day workshop held in Edinburgh on 10 July 2014 to discuss Trial Forge and how to advance this initiative. We first outline the problem of inefficiency in randomised trials and go on to describe Trial Forge. We present participants' views on the processes in the life of a randomised trial that should be covered by Trial Forge.General support existed at the workshop for the Trial Forge approach to increase the evidence base for making randomised trial decisions and for improving trial efficiency. Agreed upon key processes included choosing the right research question; logistical planning for delivery, training of staff, recruitment, and retention; data management and dissemination; and close down. The process of linking to existing initiatives where possible was considered crucial. Trial Forge will not be a guideline or a checklist but a 'go to' website for research on randomised trials methods, with a linked programme of applied methodology research, coupled to an effective evidence-dissemination process. Moreover, it will support an informal network of interested trialists who meet virtually (online) and occasionally in person to build capacity and knowledge in the design and conduct of efficient randomised trials.Some of the resources invested in randomised trials are wasted because of limited evidence upon which to base many aspects of design, conduct, analysis, and reporting of clinical trials. Trial Forge will help to address this lack of evidence.

  7. Open-source mobile digital platform for clinical trial data collection in low-resource settings

    Science.gov (United States)

    van Dam, Joris; Omondi Onyango, Kevin; Midamba, Brian; Groosman, Nele; Hooper, Norman; Spector, Jonathan; Pillai, Goonaseelan (Colin); Ogutu, Bernhards

    2017-01-01

    Background Governments, universities and pan-African research networks are building durable infrastructure and capabilities for biomedical research in Africa. This offers the opportunity to adopt from the outset innovative approaches and technologies that would be challenging to retrofit into fully established research infrastructures such as those regularly found in high-income countries. In this context we piloted the use of a novel mobile digital health platform, designed specifically for low-resource environments, to support high-quality data collection in a clinical research study. Objective Our primary aim was to assess the feasibility of a using a mobile digital platform for clinical trial data collection in a low-resource setting. Secondarily, we sought to explore the potential benefits of such an approach. Methods The investigative site was a research institute in Nairobi, Kenya. We integrated an open-source platform for mobile data collection commonly used in the developing world with an open-source, standard platform for electronic data capture in clinical trials. The integration was developed using common data standards (Clinical Data Interchange Standards Consortium (CDISC) Operational Data Model), maximising the potential to extend the approach to other platforms. The system was deployed in a pharmacokinetic study involving healthy human volunteers. Results The electronic data collection platform successfully supported conduct of the study. Multidisciplinary users reported high levels of satisfaction with the mobile application and highlighted substantial advantages when compared with traditional paper record systems. The new system also demonstrated a potential for expediting data quality review. Discussion and Conclusions This pilot study demonstrated the feasibility of using a mobile digital platform for clinical research data collection in low-resource settings. Sustainable scientific capabilities and infrastructure are essential to attract and

  8. Gigabit network-based three-dimensional trial service on media delivery platform

    Science.gov (United States)

    Kim, Nac-Woo; Son, Seung-Chul; Lee, Byung-Tak

    2011-09-01

    Recently, as effective demand for high-quality, large-capacity content such as three-dimensional (3D), multiangle, and gigabit-web has increased, a network infrastructure capable of satisfying future broadcast and communication service requirements is required. In this paper, we introduce a convergence service based on a gigabit network and then propose a technique for delivering gigabit 3D content. Here, the term 3D content delivery technique refers to an overlay-multicast-based distributed service platform that is comprised of a media relay agent and a management server. The service platform is designed to back up both live video and file-based video streaming. Using this platform, we can provide 3D remote education and 3D multiangle services via 3D-based video streaming between a service provider and service consumers dispersed at different locations. To evaluate our 3D content delivery technique, we run a series of trials of gigabit network-based 3D trial services to service subscribers. Then, we conduct a survey to measure user satisfaction with the 3D delivery service and simulated network and service quality. From experimental results, we confirm that this type of distributed service platform can be used as the delivery framework for applications such as realistic 3D-based seminars or 3D video conferences.

  9. Anteroposterior glide versus rotating platform low contact stress (LCS knee arthroplasty: a randomised controlled trial

    Directory of Open Access Journals (Sweden)

    Wynn-Jones Charles

    2007-08-01

    Full Text Available Abstract Background Fifty thousand knee replacements are performed annually in the UK at an estimated cost of £150 million. Post-operative improvement depends on a number of factors including implant design and patient associated factors. To our knowledge there are no published study's comparing the results of AP glide and rotating platform designs of LCS knee arthroplasty. Therefore we feel that a study is required to investigate and compare the effects of two types of LCS total knee arthroplasty on joint proprioception and range of motion. Methods/Design Patients will be randomised to receive either a LCS AP glide or Rotating platform prosthesis. Clinical scores (Oxford knee score, American knee society score, EuroQol, range of motion and proprioception will be assessed prior to and at 3,6, 12 and 24 months after the operation. Proprioception will be assessed in terms of absolute error angle (mean difference between the target angle and the response angle. Knee angles will be measured in degrees using an electromagnetic tracking device, Polhemus 3Space Fastrak that detects positions of sensors placed on the test limb. Student's t-test will be used to compare the mean of two groups. Discussion Evidence is lacking concerning the best prosthesis to use for patients undergoing total knee replacement. This pragmatic randomised trial will test the null hypothesis that anteroposterior glide LCS knee arthroplasty does not result in better post operative knee motion and proprioception as compared to rotating platform LCS knee. Trial Registration ISRCTN52943804

  10. Effects of tai chi qigong on psychosocial well-being among hidden elderly, using elderly neighborhood volunteer approach: a pilot randomized controlled trial

    Science.gov (United States)

    Chan, Aileen WK; Yu, Doris SF; Choi, KC

    2017-01-01

    Purpose To test the feasibility and preliminary effectiveness of a tai chi qigong program with the assistance of elderly neighborhood volunteers in strengthening social networks and enhancing the psychosocial well-being of hidden elderly. Patients and methods “Hidden elderly” is a term used to describe older adults who are socially isolated and refuse social participation. This pilot randomized controlled trial recruited 48 older adults aged 60 or above who did not engage in any social activity. They were randomized into tai chi qigong (n=24) and standard care control (n=24) groups. The former group underwent a three-month program of two 60-minute sessions each week, with the socially active volunteers paired up with them during practice. Standard care included regular home visits by social workers. Primary outcomes were assessed by means of the Lubben social network and De Jong Gieveld loneliness scales, and by a revised social support questionnaire. Secondary outcomes were covered by a mental health inventory and the Rosenberg self-esteem scale, and quality of life by using the 12-Item Short Form Health Survey. Data was collected at baseline, and at three and six months thereafter. Results The generalized estimating equations model revealed general improvement in outcomes among participants on the tai chi qigong program. In particular, participants reported a significantly greater improvement on the loneliness scale (B=−1.32, 95% confidence interval [CI] −2.54 to −0.11, P=0.033) and the satisfaction component of the social support questionnaire (B=3.43, 95% CI 0.10–6.76, P=0.044) than the control group. Conclusion The pilot study confirmed that tai chi qigong with elderly neighborhood volunteers is a safe and feasible social intervention for hidden elderly. Its potential benefits in improving social and psychological health suggest the need for a full-scale randomized controlled trial to reveal its empirical effects. PMID:28115837

  11. Effects of tai chi qigong on psychosocial well-being among hidden elderly, using elderly neighborhood volunteer approach: a pilot randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Chan AW

    2017-01-01

    Full Text Available Aileen WK Chan, Doris SF Yu, KC Choi The Nethersole School of Nursing, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong SAR Purpose: To test the feasibility and preliminary effectiveness of a tai chi qigong program with the assistance of elderly neighborhood volunteers in strengthening social networks and enhancing the psychosocial well-being of hidden elderly. Patients and methods: “Hidden elderly” is a term used to describe older adults who are socially isolated and refuse social participation. This pilot randomized controlled trial recruited 48 older adults aged 60 or above who did not engage in any social activity. They were randomized into tai chi qigong (n=24 and standard care control (n=24 groups. The former group underwent a three-month program of two 60-minute sessions each week, with the socially active volunteers paired up with them during practice. Standard care included regular home visits by social workers. Primary outcomes were assessed by means of the Lubben social network and De Jong Gieveld loneliness scales, and by a revised social support questionnaire. Secondary outcomes were covered by a mental health inventory and the Rosenberg self-esteem scale, and quality of life by using the 12-Item Short Form Health Survey. Data was collected at baseline, and at three and six months thereafter. Results: The generalized estimating equations model revealed general improvement in outcomes among participants on the tai chi qigong program. In particular, participants reported a significantly greater improvement on the loneliness scale (B=-1.32, 95% confidence interval [CI] -2.54 to -0.11, P=0.033 and the satisfaction component of the social support questionnaire (B=3.43, 95% CI 0.10–6.76, P=0.044 than the control group. Conclusion: The pilot study confirmed that tai chi qigong with elderly neighborhood volunteers is a safe and feasible social intervention for hidden elderly. Its potential benefits in

  12. Hidden loss

    DEFF Research Database (Denmark)

    Kieffer-Kristensen, Rikke; Johansen, Karen Lise Gaardsvig

    2013-01-01

    to participate. RESULTS: All children were affected by their parents' ABI and the altered family situation. The children's expressions led the authors to identify six themes, including fear of losing the parent, distress and estrangement, chores and responsibilities, hidden loss, coping and support. The main...... the ill parent. These findings contribute to a deeper understanding of the traumatic process of parental ABI that some children experience and emphasize the importance of family-centred interventions that include the children....

  13. The Egyptian clinical trials’ registry profile: Analysis of three trial registries (International Clinical Trials Registry Platform, Pan-African Clinical Trials Registry and clinicaltrials.gov

    Directory of Open Access Journals (Sweden)

    Ahmed A. Zeeneldin

    2016-01-01

    Full Text Available Registering clinical trials (CTs in public domains enhances transparency, increases trust in research, improves participation and safeguards against publication bias. This work was done to study the profile of clinical research in Egypt in three CT registries with different scopes: the WHO International CT Registry Platform (ICTRP, the continental Pan-African CT Registry (PACTR and the US clinicaltrials.gov (CTGR. In March 2014, ICTRP, PACTR and CTGR were searched for clinical studies conducted in Egypt. It was found that the number of studies conducted in Egypt (percentage was 686 (0.30% in ICTRP, 56 (11.3% in PACTR and 548 (0.34% in CTGR. Most studies were performed in universities and sponsored by university/organization, industry or individual researchers. Inclusion of adults from both genders predominated. The median number of participants per study in the three registries ranged between 63 and 155. The conditions researched differed among the three registries and study purpose was mostly treatment followed by prevention. Endpoints were mostly efficacy followed by safety. Observational:Interventional studies (i.e. clinical trials represented 15.5%:84.5% in ICTRP, 0%:100% in PACTR and 16.4%:83.6% in CTGR. Most interventions were drugs or procedures. Observational studies were mostly prospective and cohort studies. Most CTs were phase 3 and tested drugs or procedures. Parallel group assignment and random allocation predominated. Blinding was implemented in many of trials and was mostly double-blind. We conclude that CTs from Egypt in trial registries are apparently low and do not accurately reflect clinical research conducted in Egypt or its potential. Development of an Egyptian CT registry is eagerly needed. Registering all Egyptian CTs in public domains is highly recommended.

  14. ITS Platform

    DEFF Research Database (Denmark)

    Tøfting, Svend; Lahrmann, Harry; Agerholm, Niels

    2014-01-01

    Aalborg University and two local companies have over the past four years developed and tested an ITS Platform, which can be used for communication with cars and for providing a number of services to the drivers. The purpose has been to perform a technological test of the possible use of a hidden ...... not have to be very intelligent. This is gradually taken over by applications on smart phones. The ITS Platform with 425 test drivers is now completely developed and can be used for technological testing of e.g. payment systems.......Aalborg University and two local companies have over the past four years developed and tested an ITS Platform, which can be used for communication with cars and for providing a number of services to the drivers. The purpose has been to perform a technological test of the possible use of a hidden...

  15. Assessing Maternal Capabilities in the SHINE Trial: Highlighting a Hidden Link in the Causal Pathway to Child Health.

    Science.gov (United States)

    Matare, Cynthia R; Mbuya, Mduduzi N N; Pelto, Gretel; Dickin, Katherine L; Stoltzfus, Rebecca J

    2015-12-15

    A potential bottleneck for increasing the adoption of child health interventions has been limited attention to designing actions that are built on the essential role that caregivers play in determining their effectiveness. In the Sanitation Hygiene Infant Nutrition Efficacy (SHINE) trial, we utilize the concept of maternal capabilities to examine participants' skills and attributes that affect their ability to provide appropriate care for their young child, fully engage with trial interventions, and influence the response to these interventions at the household level. We hypothesize that the impact of SHINE interventions on child stunting and anemia will be modified by these maternal capabilities. Drawing upon multiple theories, we identify and define critical maternal capabilities domains, and describe how they are measured in the trial. Description of maternal capabilities and their role as potential modifiers on impact will increase understanding of the impact of SHINE interventions, and the generalizability of our findings.

  16. College English Hidden Curriculum Construction Based on WeChat Platform%基于微信平台的大学英语隐性课程建设

    Institute of Scientific and Technical Information of China (English)

    赵婷; 李繁

    2015-01-01

    With the rapid develop of new media and the appearance of WeChat since 2011, WeChat platform has been developing rapidly and it occupies a large proportion in the network communication modes of college students. Learning habits of contemporary college students have changed under the influ-ence of new media platform. Their learning habits mainly presented as: the tendency of short and simple learning materials, the tendency of quick and easy way of learning, the tendency of intuitive and orderly learning tasks, and the tendency of interactive and participatory ways of learning. Wechat platform has many advantages in the construction of college English hidden curriculum construction such as the diver-sity of the transmission modes, the fast speed of transmission, the dissemination of information, the timeli-ness of information interaction and the richness of the message content. College English hidden curricu-lum construction based on WeChat platform can be implemented from the perspectives of “micro” class-room construction, “micro” material resources, “micro” team tasks, “micro” competition, “micro” assess-ment system,“micro”database and“micro”life platform, which will eventually extend hidden curriculum learning to teacher and students’“micro”life.%自2011年微信出现后,微信平台的发展势头迅猛,并在大学生网络通讯方式中占有很大比重。在微信平台的影响下,当代大学生的学习习惯也随之发生了变化。主要呈现为:倾向短小简洁的学习材料;倾向快速浅显的学习方式;倾向直观有序的学习任务;倾向互动参与性的学习方法。微信平台在大学英语隐性课程构建中具有传播方式的多样性、传播速度的即时性、传播信息的生动性、信息交互的时效性、消息内容的丰富性等优势。基于微信平台构建大学英语隐性课程,可从“微”化课堂构建、“微”材料资源、“微”团队

  17. Clinical trials in allied medical fields: A cross-sectional analysis of World Health Organization International Clinical Trial Registry Platform

    Directory of Open Access Journals (Sweden)

    S. Kannan

    2016-03-01

    Conclusion: The number of clinical trials done in allied fields of medicine other than the allopathic system has lowered down, and furthermore focus is required regarding the methodological quality of these trials and more support from various organizations.

  18. ITS Platform

    DEFF Research Database (Denmark)

    Tøfting, Svend; Lahrmann, Harry; Agerholm, Niels

    2014-01-01

    Aalborg University and two local companies have over the past four years developed and tested an ITS Platform, which can be used for communication with cars and for providing a number of services to the drivers. The purpose has been to perform a technological test of the possible use of a hidden ...... not have to be very intelligent. This is gradually taken over by applications on smart phones. The ITS Platform with 425 test drivers is now completely developed and can be used for technological testing of e.g. payment systems....

  19. A Response Adaptive Randomization Platform Trial for Efficient Evaluation of Ebola Virus Treatments: A Model for Pandemic Response

    Science.gov (United States)

    Berry, Scott M.; Petzold, Elizabeth A.; Dull, Peter; Thielman, Nathan M.; Cunningham, Coleen K.; Corey, G. Ralph; McClain, Micah T.; Hoover, David L.; Russell, James; Griffiss, J. McLeod; Woods, Christopher W.

    2017-01-01

    The outbreak of Ebola Virus Disease (EVD) in West Africa is the largest ever recorded. Numerous treatment alternatives for EVD have been considered, including widely available re-purposed drugs, but initiation of enrollment into clinical trials has been limited. The proposed trial is an adaptive platform design. Multiple agents and combinations will be investigated simultaneously. Additionally, new agents may enter the trial as they become available, and failing agents may be removed. In order to accommodate the many possible agents and combinations, a critical feature of this design is the use of response adaptive randomization to assign treatment regimens. As the trial progresses, the randomization ratio evolves to favor the arms that are performing better, making the design also suitable for all-cause pandemic preparedness planning. The study was approved by US and Sierra Leone ethics committees, and reviewed by the US FDA. Additionally, data management, drug supply lines, and local sites were prepared. However, in response to the declining epidemic seen in February 2015, the trial was not initiated. Sierra Leone remains ready to rapidly activate the protocol as an emergency response trial in the event of a resurgence of EVD. (ClinicalTrials.gov Identifier: NCT02380625) In summary, we have designed a single controlled trial capable of efficiently identifying highly effective or failing regimens among a rapidly evolving list of proposed therapeutic alternatives for EVD and to treat the patients within the trial effectively based on accruing data. Provision of these regimens, if found safe and effective, would have a major impact on future epidemics by providing effective treatment options. PMID:26768569

  20. Effects of tai chi qigong on psychosocial well-being among hidden elderly, using elderly neighborhood volunteer approach: a pilot randomized controlled trial

    OpenAIRE

    Chan AW; Yu DS; Choi KC

    2017-01-01

    Aileen WK Chan, Doris SF Yu, KC Choi The Nethersole School of Nursing, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong SAR Purpose: To test the feasibility and preliminary effectiveness of a tai chi qigong program with the assistance of elderly neighborhood volunteers in strengthening social networks and enhancing the psychosocial well-being of hidden elderly. Patients and methods: “Hidden elderly” is a term used to describe older adults w...

  1. Our Hidden Prejudices, on Trial

    Science.gov (United States)

    Glenn, David

    2008-01-01

    In October 2006, a New Hampshire police officer named Michael Briggs was shot to death in an alley. His accused killer, Michael Addison, has been charged with capital murder. It is the state's first death-penalty case in more than 30 years, and it is racially fraught: Addison is African-American, and Briggs was white. New Hampshire has a long list…

  2. Chiaro Networks' Enstara IP/MPLS platform selected by CERN for trans-Atlantic trial

    CERN Multimedia

    2004-01-01

    "Chiaro Networks, the developer of true infrastructure-class Internet Protocol/Multi-Protocol Label Switching (IP/MPLS) platforms, today announced that its Enstara router has been selected by the European Organization for Nuclear Research (CERN) for its DataTAG project" (1 page)

  3. Effect of Dynamic Platform Lateral Step-Up versus Stable Platform Lateral Step-Up Weight Bearing Exercise in Hip Abductor Strengthening on Healthy Male Volunteers - Randomized Clinical Trial

    Directory of Open Access Journals (Sweden)

    Jagatheesan Alagesan

    2011-07-01

    Full Text Available Objective & Background: To determine the effect of the dynamic platform lateral step-up and stable platform lateral step-up weight bearing standing exercise in strengthening of hip abductor. Many researchers have reported that strengthening of hip muscles as important component especially hip abductors in lower extremity rehabilitation program. Study Design: Single blinded randomized comparative clinical trial. Methodology: Sixty five healthy college going male subjects (Age group of 18 – 24 years volunteered for this study. They were randomly assigned to one of the 2 groups. One group received the dynamic platform lateral step-up and the other received stable platform lateral step-up weight bearing standing exercise. The strength measurements were recorded using hand held dynamometer. Results: The results indicate that both groups had a positive effect on the outcome measures. The strength of hip abductors in dynamic platform group improved from a mean value (SD of 19.47(3.59 to 26.93(3.19 and in stable platform group from 19.07(2.32 to 22.67(2.46. Significant difference is also observed between the two groups at p value .05. Conclusion: The study shows that dynamic platform lateral step-up exercise is more beneficial than stable platform lateral step-up weight bearing standing exercise in improving hip abductor muscle strength.

  4. An exploratory evaluation of Take Control: A novel computer-delivered behavioral platform for placebo-controlled pharmacotherapy trials for alcohol use disorder.

    Science.gov (United States)

    Devine, Eric G; Ryan, Megan L; Falk, Daniel E; Fertig, Joanne B; Litten, Raye Z

    2016-09-01

    Placebo-controlled pharmacotherapy trials for alcohol use disorder (AUD) require an active behavioral platform to avoid putting participants at risk for untreated AUD and to better assess the effectiveness of the medication. Therapist-delivered platforms (TDP) can be costly and present a risk to study design because of the variability in therapist fidelity. Take Control is a novel computer-delivered behavioral platform developed for use in pharmacotherapy trials sponsored by the National Institute on Alcohol Abuse and Alcoholism Clinical Investigations Group (NCIG). This behavioral platform was developed with the goal of reducing trial implementation costs and limiting potential bias introduced by therapists providing TDP. This exploratory study is the first to compare Take Control with TDP on measures related to placebo response rate, medication adherence, and participant retention. Data were drawn from the placebo arms of four multisite, double-blind, randomized controlled trials (RCT) for AUD conducted by NCIG from 2007 to 2015. Data were compared from subjects receiving TDP (n=156) in two RCTs and Take Control (n=155) in another two RCTs. Placebo response rate, as represented by weekly percentage of heavy drinking days, was similar between groups. Subjects who received Take Control had a higher rate of medication adherence than those who received TDP. Subject retention was not significantly different between groups. The findings suggest that Take Control is comparable to TDP on measures of retention, medication adherence, and placebo response. Additional research is needed to evaluate Take Control directly against TDPs in a randomized trial.

  5. Use of a Novel Artificial Intelligence Platform on Mobile Devices to Assess Dosing Compliance in a Phase 2 Clinical Trial in Subjects With Schizophrenia

    Science.gov (United States)

    2017-01-01

    Background Accurately monitoring and collecting drug adherence data can allow for better understanding and interpretation of the outcomes of clinical trials. Most clinical trials use a combination of pill counts and self-reported data to measure drug adherence, despite the drawbacks of relying on these types of indirect measures. It is assumed that doses are taken, but the exact timing of these events is often incomplete and imprecise. Objective The objective of this pilot study was to evaluate the use of a novel artificial intelligence (AI) platform (AiCure) on mobile devices for measuring medication adherence, compared with modified directly observed therapy (mDOT) in a substudy of a Phase 2 trial of the α7 nicotinic receptor agonist (ABT-126) in subjects with schizophrenia. Methods AI platform generated adherence measures were compared with adherence inferred from drug concentration measurements. Results The mean cumulative pharmacokinetic adherence over 24 weeks was 89.7% (standard deviation [SD] 24.92) for subjects receiving ABT-126 who were monitored using the AI platform, compared with 71.9% (SD 39.81) for subjects receiving ABT-126 who were monitored by mDOT. The difference was 17.9% (95% CI -2 to 37.7; P=.08). Conclusions Using drug levels, this substudy demonstrates the potential of AI platforms to increase adherence, rapidly detect nonadherence, and predict future nonadherence. Subjects monitored using the AI platform demonstrated a percentage change in adherence of 25% over the mDOT group. Subjects were able to use the technology successfully for up to 6 months in an ambulatory setting with early termination rates that are comparable to subjects outside of the substudy. Trial Registration ClinicalTrials.gov NCT01655680 https://clinicaltrials.gov/ct2/show/NCT01655680?term=NCT01655680 PMID:28223265

  6. Augmented reality telementoring (ART) platform: a randomized controlled trial to assess the efficacy of a new surgical education technology.

    Science.gov (United States)

    Vera, Angelina M; Russo, Michael; Mohsin, Adnan; Tsuda, Shawn

    2014-12-01

    Laparoscopic skills training has evolved over recent years. However, conveying a mentor's directions using conventional methods, without realistic on-screen visual cues, can be difficult and confusing. To facilitate laparoscopic skill transference, an augmented reality telementoring (ART) platform was designed to overlay the instruments of a mentor onto the trainee's laparoscopic monitor. The aim of this study was to compare the effectiveness of this new teaching modality to traditional methods in novices performing an intracorporeal suturing task. Nineteen pre-medical and medical students were randomized into traditional mentoring (n = 9) and ART (n = 10) groups for a laparoscopic suturing and knot-tying task. Subjects received either traditional mentoring or ART for 1 h on the validated fundamentals of laparoscopic surgery intracorporeal suturing task. Tasks for suturing were recorded and scored for time and errors. Results were analyzed using means, standard deviation, power regression analysis, correlation coefficient, analysis of variance, and student's t test. Using Wright's cumulative average model (Y = aX (b)) the learning curve slope was significantly steeper, demonstrating faster skill acquisition, for the ART group (b = -0.567, r (2) = 0.92) than the control group (b = -0.453, r (2) = 0.74). At the end of 10 repetitions or 1 h of practice, the ART group was faster versus traditional (mean 167.4 vs. 242.4 s, p = 0.014). The ART group also had fewer fails (8) than the traditional group (13). The ART Platform may be a more effective training technique in teaching laparoscopic skills to novices compared to traditional methods. ART conferred a shorter learning curve, which was more pronounced in the first 4 trials. ART reduced the number of failed attempts and resulted in faster suture times by the end of the training session. ART may be a more effective training tool in laparoscopic surgical training for complex tasks than traditional methods.

  7. Partially Hidden Markov Models

    DEFF Research Database (Denmark)

    Forchhammer, Søren Otto; Rissanen, Jorma

    1996-01-01

    Partially Hidden Markov Models (PHMM) are introduced. They differ from the ordinary HMM's in that both the transition probabilities of the hidden states and the output probabilities are conditioned on past observations. As an illustration they are applied to black and white image compression wher...

  8. Use of a Novel Artificial Intelligence Platform on Mobile Devices to Assess Dosing Compliance in a Phase 2 Clinical Trial in Subjects With Schizophrenia.

    Science.gov (United States)

    Bain, Earle E; Shafner, Laura; Walling, David P; Othman, Ahmed A; Chuang-Stein, Christy; Hinkle, John; Hanina, Adam

    2017-02-21

    Accurately monitoring and collecting drug adherence data can allow for better understanding and interpretation of the outcomes of clinical trials. Most clinical trials use a combination of pill counts and self-reported data to measure drug adherence, despite the drawbacks of relying on these types of indirect measures. It is assumed that doses are taken, but the exact timing of these events is often incomplete and imprecise. The objective of this pilot study was to evaluate the use of a novel artificial intelligence (AI) platform (AiCure) on mobile devices for measuring medication adherence, compared with modified directly observed therapy (mDOT) in a substudy of a Phase 2 trial of the α7 nicotinic receptor agonist (ABT-126) in subjects with schizophrenia. AI platform generated adherence measures were compared with adherence inferred from drug concentration measurements. The mean cumulative pharmacokinetic adherence over 24 weeks was 89.7% (standard deviation [SD] 24.92) for subjects receiving ABT-126 who were monitored using the AI platform, compared with 71.9% (SD 39.81) for subjects receiving ABT-126 who were monitored by mDOT. The difference was 17.9% (95% CI -2 to 37.7; P=.08). Using drug levels, this substudy demonstrates the potential of AI platforms to increase adherence, rapidly detect nonadherence, and predict future nonadherence. Subjects monitored using the AI platform demonstrated a percentage change in adherence of 25% over the mDOT group. Subjects were able to use the technology successfully for up to 6 months in an ambulatory setting with early termination rates that are comparable to subjects outside of the substudy. ClinicalTrials.gov NCT01655680 https://clinicaltrials.gov/ct2/show/NCT01655680?term=NCT01655680.

  9. Entanglement without hidden nonlocality

    Science.gov (United States)

    Hirsch, Flavien; Túlio Quintino, Marco; Bowles, Joseph; Vértesi, Tamás; Brunner, Nicolas

    2016-11-01

    We consider Bell tests in which the distant observers can perform local filtering before testing a Bell inequality. Notably, in this setup, certain entangled states admitting a local hidden variable model in the standard Bell scenario can nevertheless violate a Bell inequality after filtering, displaying so-called hidden nonlocality. Here we ask whether all entangled states can violate a Bell inequality after well-chosen local filtering. We answer this question in the negative by showing that there exist entangled states without hidden nonlocality. Specifically, we prove that some two-qubit Werner states still admit a local hidden variable model after any possible local filtering on a single copy of the state.

  10. eEduHeart I: A Multicenter, Randomized, Controlled Trial Investigating the Effectiveness of a Cardiac Web-Based eLearning Platform - Rationale and Study Design.

    Science.gov (United States)

    Frederix, Ines; Vandenberk, Thijs; Janssen, Leen; Geurden, Anne; Vandervoort, Pieter; Dendale, Paul

    2017-01-01

    Cardiac telerehabilitation includes, in its most comprehensive format, telemonitoring, telecoaching, social interaction, and eLearning. The specific role of eLearning, however, was seldom assessed. The aim of eEduHeart I is to investigate the medium-term effectiveness of the addition of a cardiac web-based eLearing platform to conventional cardiac care. In this prospective, multicenter randomized, controlled trial, 1,000 patients with coronary artery disease will be randomized 1:1 to an intervention group (receiving 1-month unrestricted access to the cardiac eLearning platform in addition to conventional cardiac care) or to conventional cardiac care alone. The primary endpoint is health-related quality of life, assessed by the HeartQoL questionnaire at the 1- and 3-month follow-ups. Secondary endpoints include pathology-specific knowledge and self-reported eLearning platform user experience. Data on the eLearning platform usage will be gathered through web logging during the study period. eEduHeart I will be one of the first studies to report on the added value of eLearning. If the intervention is proven effective, current cardiac telerehabilitation programs can be augmented by including eLearning, too. The platform can then be used as a model for other chronic diseases in which patient education plays a key role. © 2016 S. Karger AG, Basel.

  11. Hidden circuits and argumentation

    Science.gov (United States)

    Leinonen, Risto; Kesonen, Mikko H. P.; Hirvonen, Pekka E.

    2016-11-01

    Despite the relevance of DC circuits in everyday life and schools, they have been shown to cause numerous learning difficulties at various school levels. In the course of this article, we present a flexible method for teaching DC circuits at lower secondary level. The method is labelled as hidden circuits, and the essential idea underlying hidden circuits is in hiding the actual wiring of DC circuits, but to make their behaviour evident for pupils. Pupils are expected to find out the wiring of the circuit which should enhance their learning of DC circuits. We present two possible ways to utilise hidden circuits in a classroom. First, they can be used to test and enhance pupils’ conceptual understanding when pupils are expected to find out which one of the offered circuit diagram options corresponds to the actual circuit shown. This method aims to get pupils to evaluate the circuits holistically rather than locally, and as a part of that aim this method highlights any learning difficulties of pupils. Second, hidden circuits can be used to enhance pupils’ argumentation skills with the aid of argumentation sheet that illustrates the main elements of an argument. Based on the findings from our co-operating teachers and our own experiences, hidden circuits offer a flexible and motivating way to supplement teaching of DC circuits.

  12. How Hidden Can Be Even More Hidden?

    CERN Document Server

    Fraczek, Wojciech; Szczypiorski, Krzysztof

    2011-01-01

    The paper presents Deep Hiding Techniques (DHTs) that define general techniques that can be applied to every network steganography method to improve its undetectability and make steganogram extraction harder to perform. We define five groups of techniques that can make steganogram less susceptible to detection and extraction. For each of the presented group, examples of the usage are provided based on existing network steganography methods. To authors' best knowledge presented approach is the first attempt in the state of the art to systematically describe general solutions that can make steganographic communication more hidden and steganogram extraction harder to perform.

  13. Search for Hidden Particles

    CERN Multimedia

    The SHiP Experiment is a new general-purpose fixed target facility at the SPS to search for hidden particles as predicted by a very large number of recently elaborated models of Hidden Sectors which are capable of accommodating dark matter, neutrino oscillations, and the origin of the full baryon asymmetry in the Universe. Specifically, the experiment is aimed at searching for very weakly interacting long lived particles including Heavy Neutral Leptons - right-handed partners of the active neutrinos; light supersymmetric particles - sgoldstinos, etc.; scalar, axion and vector portals to the hidden sector. The high intensity of the SPS and in particular the large production of charm mesons with the 400 GeV beam allow accessing a wide variety of light long-lived exotic particles of such models and of SUSY. Moreover, the facility is ideally suited to study the interactions of tau neutrinos.

  14. A Randomized Trial Comparing Classical Participatory Design to VandAID, an Interactive CrowdSourcing Platform to Facilitate User-Centered Design.

    Science.gov (United States)

    Dufendach, Kevin R; Koch, Sabine; Unertl, Kim M; Lehmann, Christoph U

    2017-04-28

    Early involvement of stakeholders in the design of medical software is particularly important due to the need to incorporate complex knowledge and actions associated with clinical work. Standard user-centered design methods include focus groups and participatory design sessions with individual stakeholders, which generally limit user involvement to a small number of individuals due to the significant time investments from designers and end users. The goal of this project was to reduce the effort for end users to participate in co-design of a software user interface by developing an interactive web-based crowdsourcing platform. In a randomized trial, we compared a new web-based crowdsourcing platform to standard participatory design sessions. We developed an interactive, modular platform that allows responsive remote customization and design feedback on a visual user interface based on user preferences. The responsive canvas is a dynamic HTML template that responds in real time to user preference selections. Upon completion, the design team can view the user's interface creations through an administrator portal and download the structured selections through a REDCap interface. We have created a software platform that allows users to customize a user interface and see the results of that customization in real time, receiving immediate feedback on the impact of their design choices. Neonatal clinicians used the new platform to successfully design and customize a neonatal handoff tool. They received no specific instruction and yet were able to use the software easily and reported high usability. VandAID, a new web-based crowdsourcing platform, can involve multiple users in user-centered design simultaneously and provides means of obtaining design feedback remotely. The software can provide design feedback at any stage in the design process, but it will be of greatest utility for specifying user requirements and evaluating iterative designs with multiple options.

  15. Solar Hidden Photon Search

    CERN Document Server

    Schwarz, Matthias; Redondo, Javier; Ringwald, Andreas; Wiedemann, Guenter

    2011-01-01

    The Solar Hidden Photon Search (SHIPS) is a joint astroparticle project of the Hamburger Sternwarte and DESY. The main target is to detect the solar emission of a new species of particles, so called Hidden Photons (HPs). Due to kinetic mixing, photons and HPs can convert into each other as they propagate. A small number of solar HPs - originating from photon to HP oscillations in the interior of the Sun - can be converted into photons in a long vacuum pipe pointing to the Sun - the SHIPS helioscope.

  16. Solar Hidden Photon Search

    Energy Technology Data Exchange (ETDEWEB)

    Schwarz, Matthias; Wiedemann, Guenter [Hamburg Univ. (Germany). Sternwarte; Lindner, Axel; Ringwald, Andreas [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Redondo, Javier [Max-Planck-Institut fuer Physik und Astrophysik, Muenchen (Germany)

    2011-11-15

    The Solar Hidden Photon Search (SHIPS) is a joint astroparticle project of the Hamburger Sternwarte and DESY. The main target is to detect the solar emission of a new species of particles, so called Hidden Photons (HPs). Due to kinetic mixing, photons and HPs can convert into each other as they propagate. A small number of solar HPs - originating from photon to HP oscillations in the interior of the Sun - can be converted into photons in a long vacuum pipe pointing to the Sun - the SHIPS helioscope. (orig.)

  17. Hidden neural networks

    DEFF Research Database (Denmark)

    Krogh, Anders Stærmose; Riis, Søren Kamaric

    1999-01-01

    A general framework for hybrids of hidden Markov models (HMMs) and neural networks (NNs) called hidden neural networks (HNNs) is described. The article begins by reviewing standard HMMs and estimation by conditional maximum likelihood, which is used by the HNN. In the HNN, the usual HMM probability...... parameters are replaced by the outputs of state-specific neural networks. As opposed to many other hybrids, the HNN is normalized globally and therefore has a valid probabilistic interpretation. All parameters in the HNN are estimated simultaneously according to the discriminative conditional maximum...... likelihood criterion. The HNN can be viewed as an undirected probabilistic independence network (a graphical model), where the neural networks provide a compact representation of the clique functions. An evaluation of the HNN on the task of recognizing broad phoneme classes in the TIMIT database shows clear...

  18. Coupling of Hidden Sector

    CERN Document Server

    Królikowski, Wojciech

    2016-01-01

    A hypothetic Hidden Sector of the Universe, consisting of sterile fermions ("sterinos") and sterile mediating bosons ("sterons") of mass dimension 1 (not 2!) - the last described by an antisymmetric tensor field - requires to exist also a scalar isovector and scalar isoscalar in order to be able to construct electroweak invariant coupling (before spontaneously breaking its symmetry). The introduced scalar isoscalar might be a resonant source for the diphoton excess of 750 GeV, suggested recently by experiment.

  19. Hidden variables and hidden time in quantum theory

    OpenAIRE

    Kurakin, Pavel V.

    2005-01-01

    Bell's theorem proves only that hidden variables evolving in true physical time can't exist; still the theorem's meaning is usually interpreted intolerably wide. The concept of hidden time (and, in general, hidden space-time) is introduced. Such concept provides a whole new class of physical theories, fully compatible with current knowledge, but giving new tremendous possibilities. Those theories do not violate Bell's theorem.

  20. Systematic review of clinical trials assessing the therapeutic efficacy of visceral leishmaniasis treatments: A first step to assess the feasibility of establishing an individual patient data sharing platform.

    Directory of Open Access Journals (Sweden)

    Jacob T Bush

    2017-09-01

    Full Text Available There are an estimated 200,000 to 400,000 cases of visceral leishmaniasis (VL annually. A variety of factors are taken into account when considering the best therapeutic options to cure a patient and reduce the risk of resistance, including geographical area, malnourishment and HIV coinfection. Pooled analyses combine data from many studies to answer specific scientific questions that cannot be answered with individual studies alone. However, the heterogeneity of study design, data collection, and analysis often makes direct comparison difficult. Individual Participant Data (IPD files can be standardised and analysed, allowing detailed analysis of this merged larger pool, but only a small fraction of systematic reviews and meta-analyses currently employ pooled analysis of IPD. We conducted a systematic literature review to identify published studies and studies reported in clinical trial registries to assess the feasibility of developing a VL data sharing platform to facilitate an IPD-based analysis of clinical trial data. Studies conducted between 1983 to 2015 that reported treatment outcome were eligible.From the 2,271 documents screened, 145 published VL clinical trials were identified, with data from 26,986 patients. Methodologies varied for diagnosis and treatment outcomes, but overall the volume of data potentially available on different drugs and dose regimens identified hundreds or possibly thousands of patients per arm suitable for IPD pooled meta-analyses.A VL data sharing platform would provide an opportunity to maximise scientific use of available data to enable assessment of treatment efficacy, contribute to evidence-based clinical management and guide optimal prospective data collection.

  1. Systematic review of clinical trials assessing the therapeutic efficacy of visceral leishmaniasis treatments: A first step to assess the feasibility of establishing an individual patient data sharing platform.

    Science.gov (United States)

    Bush, Jacob T; Wasunna, Monique; Alves, Fabiana; Alvar, Jorge; Olliaro, Piero L; Otieno, Michael; Sibley, Carol Hopkins; Strub Wourgaft, Nathalie; Guerin, Philippe J

    2017-09-01

    There are an estimated 200,000 to 400,000 cases of visceral leishmaniasis (VL) annually. A variety of factors are taken into account when considering the best therapeutic options to cure a patient and reduce the risk of resistance, including geographical area, malnourishment and HIV coinfection. Pooled analyses combine data from many studies to answer specific scientific questions that cannot be answered with individual studies alone. However, the heterogeneity of study design, data collection, and analysis often makes direct comparison difficult. Individual Participant Data (IPD) files can be standardised and analysed, allowing detailed analysis of this merged larger pool, but only a small fraction of systematic reviews and meta-analyses currently employ pooled analysis of IPD. We conducted a systematic literature review to identify published studies and studies reported in clinical trial registries to assess the feasibility of developing a VL data sharing platform to facilitate an IPD-based analysis of clinical trial data. Studies conducted between 1983 to 2015 that reported treatment outcome were eligible. From the 2,271 documents screened, 145 published VL clinical trials were identified, with data from 26,986 patients. Methodologies varied for diagnosis and treatment outcomes, but overall the volume of data potentially available on different drugs and dose regimens identified hundreds or possibly thousands of patients per arm suitable for IPD pooled meta-analyses. A VL data sharing platform would provide an opportunity to maximise scientific use of available data to enable assessment of treatment efficacy, contribute to evidence-based clinical management and guide optimal prospective data collection.

  2. Hidden figures are ever present.

    Science.gov (United States)

    Mens, L H; Leeuwenberg, E L

    1988-11-01

    Preference judgments about alternative interpretations of unambiguous patterns can be explained in terms of a rivalry between a preferred and a second-best interpretation (cf. Leeuwenberg & Buffart, 1983). We tested whether this second-best interpretation corresponds to a suppressed but concurrently present interpretation or whether it merely reflects an alternative view that happens to be preferred less often. Two patterns were present immediately following each other with a very short onset asynchrony: a complete pattern and one out of three possible subpatterns of it, corresponding to the best, the second best, or an odd interpretation of the complete pattern. Subjects indicated which subpattern was presented by choosing among the three subpatterns shown after each trial. The scores, corrected for response-bias effects, indicated a relative facilitation of the second-best interpretation, in agreement with its predicted "hidden" presence. This result is more in line with theories that capitalize on the quality of the finally selected representation than with processing models aimed at reaching one single solution as fast and as economically as possible.

  3. A Web-Based Data Collection Platform for Multisite Randomized Behavioral Intervention Trials: Development, Key Software Features, and Results of a User Survey.

    Science.gov (United States)

    Modi, Riddhi A; Mugavero, Michael J; Amico, Rivet K; Keruly, Jeanne; Quinlivan, Evelyn Byrd; Crane, Heidi M; Guzman, Alfredo; Zinski, Anne; Montue, Solange; Roytburd, Katya; Church, Anna; Willig, James H

    2017-06-16

    Meticulous tracking of study data must begin early in the study recruitment phase and must account for regulatory compliance, minimize missing data, and provide high information integrity and/or reduction of errors. In behavioral intervention trials, participants typically complete several study procedures at different time points. Among HIV-infected patients, behavioral interventions can favorably affect health outcomes. In order to empower newly diagnosed HIV positive individuals to learn skills to enhance retention in HIV care, we developed the behavioral health intervention Integrating ENGagement and Adherence Goals upon Entry (iENGAGE) funded by the National Institute of Allergy and Infectious Diseases (NIAID), where we deployed an in-clinic behavioral health intervention in 4 urban HIV outpatient clinics in the United States. To scale our intervention strategy homogenously across sites, we developed software that would function as a behavioral sciences research platform. This manuscript aimed to: (1) describe the design and implementation of a Web-based software application to facilitate deployment of a multisite behavioral science intervention; and (2) report on results of a survey to capture end-user perspectives of the impact of this platform on the conduct of a behavioral intervention trial. In order to support the implementation of the NIAID-funded trial iENGAGE, we developed software to deploy a 4-site behavioral intervention for new clinic patients with HIV/AIDS. We integrated the study coordinator into the informatics team to participate in the software development process. Here, we report the key software features and the results of the 25-item survey to evaluate user perspectives on research and intervention activities specific to the iENGAGE trial (N=13). The key features addressed are study enrollment, participant randomization, real-time data collection, facilitation of longitudinal workflow, reporting, and reusability. We found 100% user

  4. Hidden attractors in dynamical systems

    Science.gov (United States)

    Dudkowski, Dawid; Jafari, Sajad; Kapitaniak, Tomasz; Kuznetsov, Nikolay V.; Leonov, Gennady A.; Prasad, Awadhesh

    2016-06-01

    Complex dynamical systems, ranging from the climate, ecosystems to financial markets and engineering applications typically have many coexisting attractors. This property of the system is called multistability. The final state, i.e., the attractor on which the multistable system evolves strongly depends on the initial conditions. Additionally, such systems are very sensitive towards noise and system parameters so a sudden shift to a contrasting regime may occur. To understand the dynamics of these systems one has to identify all possible attractors and their basins of attraction. Recently, it has been shown that multistability is connected with the occurrence of unpredictable attractors which have been called hidden attractors. The basins of attraction of the hidden attractors do not touch unstable fixed points (if exists) and are located far away from such points. Numerical localization of the hidden attractors is not straightforward since there are no transient processes leading to them from the neighborhoods of unstable fixed points and one has to use the special analytical-numerical procedures. From the viewpoint of applications, the identification of hidden attractors is the major issue. The knowledge about the emergence and properties of hidden attractors can increase the likelihood that the system will remain on the most desirable attractor and reduce the risk of the sudden jump to undesired behavior. We review the most representative examples of hidden attractors, discuss their theoretical properties and experimental observations. We also describe numerical methods which allow identification of the hidden attractors.

  5. Managing Hidden Costs of Offshoring

    DEFF Research Database (Denmark)

    Larsen, Marcus M.; Pedersen, Torben

    2014-01-01

    This chapter investigates the concept of the ‘hidden costs’ of offshoring, i.e. unexpected offshoring costs exceeding the initially expected costs. Due to the highly undefined nature of these costs, we position our analysis towards the strategic responses of firms’ realisation of hidden costs....... In this regard, we argue that a major response to the hidden costs of offshoring is the identification and utilisation of strategic mechanisms in the organisational design to eventually achieving system integration in a globally dispersed and disaggregated organisation. This is heavily moderated by a learning...

  6. Variational Infinite Hidden Conditional Random Fields

    NARCIS (Netherlands)

    Bousmalis, Konstantinos; Zafeiriou, Stefanos; Morency, Louis-Philippe; Pantic, Maja; Ghahramani, Zoubin

    2015-01-01

    Hidden conditional random fields (HCRFs) are discriminative latent variable models which have been shown to successfully learn the hidden structure of a given classification problem. An Infinite hidden conditional random field is a hidden conditional random field with a countably infinite number of

  7. Hidden Statistics of Schroedinger Equation

    Science.gov (United States)

    Zak, Michail

    2011-01-01

    Work was carried out in determination of the mathematical origin of randomness in quantum mechanics and creating a hidden statistics of Schr dinger equation; i.e., to expose the transitional stochastic process as a "bridge" to the quantum world. The governing equations of hidden statistics would preserve such properties of quantum physics as superposition, entanglement, and direct-product decomposability while allowing one to measure its state variables using classical methods.

  8. Microgenetic analysis of hidden figures

    OpenAIRE

    Marković Slobodan S.; Gvozdenović Vasilije P.

    2006-01-01

    In this study the phenomenological and processual aspects of the perception of hidden figures were compared. The question was whether the more probable percepts of hidden figures, compared to the less probable percepts, were generated in earlier stages of the perceptual process. In the pilot study the subjects were asked to say what they see in a complex linear pattern. The three most frequent and the three least frequent perceptual descriptions were selected. In the experiment the microgenes...

  9. The Hidden Subgroup Problem

    CERN Document Server

    Wang, Frédéric

    2010-01-01

    We give an overview of the Hidden Subgroup Problem (HSP) as of July 2010, including new results discovered since the survey of arXiv:quant-ph/0411037v1. We recall how the problem provides a framework for efficient quantum algorithms and present the standard methods based on coset sampling. We study the Dihedral and Symmetric HSPs and how they relate to hard problems on lattices and graphs. Finally, we conclude with the known solutions and techniques, describe connections with efficient algorithms as well as miscellaneous variants of HSP. We also bring various contributions to the topic. We show that in theory, we can solve HSP over a given group inductively: the base case is solving HSP over its simple factor groups and the inductive step is building efficient oracles over a normal subgroup N and over the factor group G/N. We apply this analysis to the Dedekindian HSP to get an alternative abelian HSP algorithm based on a change of the underlying group. We also propose a quotient reduction by the normal group...

  10. Managing Hidden Costs of Offshoring

    DEFF Research Database (Denmark)

    Larsen, Marcus M.; Pedersen, Torben

    2014-01-01

    This chapter investigates the concept of the ‘hidden costs’ of offshoring, i.e. unexpected offshoring costs exceeding the initially expected costs. Due to the highly undefined nature of these costs, we position our analysis towards the strategic responses of firms’ realisation of hidden costs. In......-by-doing process, where hidden costs motivate firms and their employees to search for new and better knowledge on how to successfully manage the organisation. We illustrate this thesis based on the case of the LEGO Group.......This chapter investigates the concept of the ‘hidden costs’ of offshoring, i.e. unexpected offshoring costs exceeding the initially expected costs. Due to the highly undefined nature of these costs, we position our analysis towards the strategic responses of firms’ realisation of hidden costs....... In this regard, we argue that a major response to the hidden costs of offshoring is the identification and utilisation of strategic mechanisms in the organisational design to eventually achieving system integration in a globally dispersed and disaggregated organisation. This is heavily moderated by a learning...

  11. The Hidden Costs of Offshoring

    DEFF Research Database (Denmark)

    Møller Larsen, Marcus; Manning, Stephan; Pedersen, Torben

    2011-01-01

    This study seeks to explain hidden costs of offshoring, i.e. unexpected costs resulting from the relocation of business tasks and activities outside the home country. We develop a model that highlights the role of complexity, design orientation and experience in explaining hidden costs of offshor...... of our study is to suggest how hidden costs of offshoring can be mitigated through an explicit orientation towards improving organizational processes and structures as well as experience with offshoring.......This study seeks to explain hidden costs of offshoring, i.e. unexpected costs resulting from the relocation of business tasks and activities outside the home country. We develop a model that highlights the role of complexity, design orientation and experience in explaining hidden costs...... of offshoring. Specifically, we propose that hidden costs can be explained by the combination of increasing structural, operational and social complexity of offshoring activities. In addition, we suggest that firm orientation towards organizational design as part of an offshoring strategy and offshoring...

  12. Assessment of Registration Information on Methodological Design of Acupuncture RCTs: A Review of 453 Registration Records Retrieved from WHO International Clinical Trials Registry Platform.

    Science.gov (United States)

    Gu, Jing; Wang, Qi; Wang, Xiaogang; Li, Hailong; Gu, Mei; Ming, Haixia; Dong, Xiaoli; Yang, Kehu; Wu, Hongyan

    2014-01-01

    Background. This review provides the first methodological information assessment of protocol of acupuncture RCTs registered in WHO International Clinical Trials Registry Platform (ICTRP). Methods. All records of acupuncture RCTs registered in the ICTRP have been collected. The methodological design assessment involved whether the randomization methods, allocation concealment, and blinding were adequate or not based on the information of registration records (protocols of acupuncture RCTs). Results. A total of 453 records, found in 11 registries, were examined. Methodological details were insufficient in registration records; there were 76.4%, 89.0%, and 21.4% records that did not provide information on randomization methods, allocation concealment, and blinding respectively. The proportions of adequate randomization methods, allocation concealment, and blinding were only 107 (23.6%), 48 (10.6%), and 210 (46.4%), respectively. The methodological design improved year by year, especially after 2007. Additionally, methodology of RCTs with ethics approval was clearly superior to those without ethics approval and different among registries. Conclusions. The overall methodological design based on registration records of acupuncture RCTs is not very well but improved year by year. The insufficient information on randomization methods, allocation concealment, and blinding maybe due to the relevant description is not taken seriously in acupuncture RCTs' registration.

  13. Short implants with a nanometer-sized CaP surface provided with either a platform-switched or platform-matched abutment connection in the posterior region : a randomized clinical trial

    NARCIS (Netherlands)

    Telleman, G.; Meijer, H. J. A.; Vissink, A.; Raghoebar, G. M.

    2013-01-01

    ObjectiveTo assess the performance of short nanorough implants (8.5mm in length) provided with either a platform-matched or a platform-switched implant-abutment connection, placed in the resorbed posterior region of partially dentate patients. Materials and MethodsA total of 149 implants with a dual

  14. Stargate of the Hidden Multiverse

    Directory of Open Access Journals (Sweden)

    Alexander Antonov

    2016-02-01

    Full Text Available Concept of Monoverse, which corresponds to the existing broad interpretation of the second postulate of the special theory of relativity, is not consistent with the modern astrophysical reality — existence of the dark matter and the dark energy, the total mass-energy of which is ten times greater than the mass-energy of the visible universe (which has been considered as the entire universe until very recent . This concept does not allow to explain their rather unusual properties — invisibility and lack of baryon content — which would seem to even destroy the very modern understanding of the term ‘matter’. However, all numerous alternative concepts of Multiverses, which have been proposed until today, are unable to explain these properties of the dark matter and dark energy. This article describes a new concept: the concept of the hidden Multiverse and hidden Supermultiverse, which mutual invisibility of parallel universes is explained by the physical reality of imaginary numbers. This concept completely explains the phenomenon of the dark matter and the dark energy. Moreover, it is shown that the dark matter and the dark energy are the experimental evidence for the existence of the hidden Multiverse. Described structure of the hidden Multiverse is fully consistent with the data obtained by the space stations WMAP and Planck. An extremely important property of the hidden Multiverse is an actual possibility of its permeation through stargate located on the Earth.

  15. Hidden photons in connection to dark matter

    Energy Technology Data Exchange (ETDEWEB)

    Andreas, Sarah; Ringwald, Andreas [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Goodsell, Mark D. [CPhT, Ecole Polytechnique, Palaiseau (France)

    2013-06-15

    Light extra U(1) gauge bosons, so called hidden photons, which reside in a hidden sector have attracted much attention since they are a well motivated feature of many scenarios beyond the Standard Model and furthermore could mediate the interaction with hidden sector dark matter.We review limits on hidden photons from past electron beam dump experiments including two new limits from such experiments at KEK and Orsay. In addition, we study the possibility of having dark matter in the hidden sector. A simple toy model and different supersymmetric realisations are shown to provide viable dark matter candidates in the hidden sector that are in agreement with recent direct detection limits.

  16. Hidden worlds in quantum physics

    CERN Document Server

    Gouesbet, Gérard

    2014-01-01

    The past decade has witnessed a resurgence in research and interest in the areas of quantum computation and entanglement. This new book addresses the hidden worlds or variables of quantum physics. Author Gérard Gouesbet studied and worked with a former student of Louis de Broglie, a pioneer of quantum physics. His presentation emphasizes the history and philosophical foundations of physics, areas that will interest lay readers as well as professionals and advanced undergraduate and graduate students of quantum physics. The introduction is succeeded by chapters offering background on relevant concepts in classical and quantum mechanics, a brief history of causal theories, and examinations of the double solution, pilot wave, and other hidden-variables theories. Additional topics include proofs of possibility and impossibility, contextuality, non-locality, classification of hidden-variables theories, and stochastic quantum mechanics. The final section discusses how to gain a genuine understanding of quantum mec...

  17. Hidden Variables or Positive Probabilities?

    CERN Document Server

    Rothman, T; Rothman, Tony

    2001-01-01

    Despite claims that Bell's inequalities are based on the Einstein locality condition, or equivalent, all derivations make an identical mathematical assumption: that local hidden-variable theories produce a set of positive-definite probabilities for detecting a particle with a given spin orientation. The standard argument is that because quantum mechanics assumes that particles are emitted in a superposition of states the theory cannot produce such a set of probabilities. We examine a paper by Eberhard who claims to show that a generalized Bell inequality, the CHSH inequality, can be derived solely on the basis of the locality condition, without recourse to hidden variables. We point out that he nonetheless assumes a set of positive-definite probabilities, which supports the claim that hidden variables or "locality" is not at issue here, positive-definite probabilities are. We demonstrate that quantum mechanics does predict a set of probabilities that violate the CHSH inequality; however these probabilities ar...

  18. The Hidden Costs of Offshoring

    DEFF Research Database (Denmark)

    Møller Larsen, Marcus; Manning, Stephan; Pedersen, Torben

    2011-01-01

    experience moderate the relationship between complexity and hidden costs negatively i.e. reduces the cost generating impact of complexity. We develop three hypotheses and test them on comprehensive data from the Offshoring Research Network (ORN). In general, we find support for our hypotheses. A key result...... of offshoring. Specifically, we propose that hidden costs can be explained by the combination of increasing structural, operational and social complexity of offshoring activities. In addition, we suggest that firm orientation towards organizational design as part of an offshoring strategy and offshoring...

  19. Hidden symmetries in jammed systems

    Science.gov (United States)

    Morse, Peter K.; Corwin, Eric I.

    2016-07-01

    There are deep, but hidden, geometric structures within jammed systems, associated with hidden symmetries. These can be revealed by repeated transformations under which these structures lead to fixed points. These geometric structures can be found in the Voronoi tesselation of space defined by the packing. In this paper we examine two iterative processes: maximum inscribed sphere (MIS) inversion and a real-space coarsening scheme. Under repeated iterations of the MIS inversion process we find invariant systems in which every particle is equal to the maximum inscribed sphere within its Voronoi cell. Using a real-space coarsening scheme we reveal behavior in geometric order parameters which is length-scale invariant.

  20. Protocol for a Randomized Controlled Trial of Proactive Web-Based Versus Telephone-Based Information and Support: Can Electronic Platforms Deliver Effective Care for Lung Cancer Patients?

    Science.gov (United States)

    Boyes, Allison W; O'Brien, Lorna; Baker, Amanda L; Henskens, Frans A; Clinton-McHarg, Tara; Bellamy, Douglas; Colburn, Glenda; Rose, Shiho; Cox, Martine E; Fradgley, Elizabeth A; Baird, Hannah; Barker, Daniel

    2016-01-01

    Background Community-based services such as telephone support lines can provide valuable informational, emotional, and practical support for cancer patients via telephone- or Web-based (live chat or email) platforms. However, very little rigorous research has examined the efficacy of such services in improving patient outcomes. Objective This study will determine whether: proactive telephone or Web-delivered support produces outcomes superior to printed information; and Web-delivered support produces outcomes comparable to telephone support. Methods A consecutive sample of 501 lung cancer outpatients will be recruited from 50 Australian health services to participate in a patient-randomized controlled trial (RCT). Eligible individuals must: be 18 years or older; have received a lung cancer diagnosis (including mesothelioma) within the previous 4 months; have an approximate life expectancy of at least 6 months; and have Internet access. Participants will be randomly allocated to receive: (1) an information booklet, (2) proactive telephone support, or (3) proactive Web support, chat, and/or email. The primary patient outcomes will be measured by the General Health Questionnaire (GHQ-12) and Health Education and Impact Questionnaire (heiQ) at 3 and 6 months post recruitment. The acceptability of proactive recruitment strategies will also be assessed. Results It is hypothesized that participants receiving telephone or Web support will report reduced distress (GHQ-12 scores that are 0.3 standard deviations (SD) lower) and greater self-efficacy (heiQ scores that are 0.3 SDs higher) than participants receiving booklets. Individuals receiving Web support will report heiQ scores within 0.29 SDs of individuals receiving telephone support. Conclusions If proven effective, electronic approaches such as live-chat and email have the potential to increase the accessibility and continuity of supportive care delivered by community-based services. This evidence may also inform the

  1. Hidden Crises and Communication : An Interactional Analysis of Hidden Crises

    NARCIS (Netherlands)

    Klarenbeek, Annette

    2011-01-01

    In this paper I describe the ways in which the communication discipline can make a hidden crisis transparent. For this purpose I examine the concept of crisis entrepreneurship from a communication point of view. Using discourse analysis, I analyse the discursive practices of crisis entrepreneurs in

  2. Platform Constellations

    DEFF Research Database (Denmark)

    Staykova, Kalina Stefanova; Damsgaard, Jan

    2016-01-01

    This research paper presents an initial attempt to introduce and explain the emergence of new phenomenon, which we refer to as platform constellations. Functioning as highly modular systems, the platform constellations are collections of highly connected platforms which co-exist in parallel...... and as such allow us to study platforms not only as separate entities, but also to investigate the relationship between several platforms offered and governed by one and the same platform provider. By investigating two case studies of indigenous platform constellations formed around the hugely popular instant...... messaging apps KakaoTalk and LINE, we are able to gain valuable insights about the nature of these new constructions and to capture and synthesize their main characteristics in a framework. Our results show that platform constellations possess unique innovative capabilities, which can improve users...

  3. Modeling Multiple Risks: Hidden Domain of Attraction

    CERN Document Server

    Mitra, Abhimanyu

    2011-01-01

    Hidden regular variation is a sub-model of multivariate regular variation and facilitates accurate estimation of joint tail probabilities. We generalize the model of hidden regular variation to what we call hidden domain of attraction. We exhibit examples that illustrate the need for a more general model and discuss detection and estimation techniques.

  4. Pentaquark states with hidden charm

    Science.gov (United States)

    Bijker, Roelof

    2017-07-01

    I develop an extension of the usual three-flavor quark model to four flavors (u, d, s and c), and discuss the classification of pentaquark states with hidden charm. This work is motivated by the recent observation of such states by the LHCb Collatoration at CERN.

  5. Microgenetic analysis of hidden figures

    Directory of Open Access Journals (Sweden)

    Marković Slobodan S.

    2006-01-01

    Full Text Available In this study the phenomenological and processual aspects of the perception of hidden figures were compared. The question was whether the more probable percepts of hidden figures, compared to the less probable percepts, were generated in earlier stages of the perceptual process. In the pilot study the subjects were asked to say what they see in a complex linear pattern. The three most frequent and the three least frequent perceptual descriptions were selected. In the experiment the microgenesis of the perception of hidden figures was investigated. The primed matching paradigm and the same-different task were used. In each experiment two types of test figures were contrasted: the more frequent and the less frequent ones. There were two prime types: identical (equal to test figures and complex (the pattern with hidden test figures. The prime duration was varied, 50 ms and 400 ms. The main result indicates that in the case of complex priming the more frequent test figures were processed significantly faster than the less frequent ones in both prime duration conditions. These results suggest that the faster the processing of a figure, the more probable the perceptual generation of this figure.

  6. Impact of platform switching on inter-proximal bone levels around short implants in the posterior region; 1-year results from a randomized clinical trial

    NARCIS (Netherlands)

    Telleman, Gerdien; Raghoebar, Gerry M.; Vissink, Arjan; Meijer, Henny J. A.; Meyer, H.J.A.

    2012-01-01

    Aim To assess the outcome of short implants (8.5 mm) supplied with a conventional platform-matched implant-abutment connection or a platform-switched design. Materials and Methods Eighty patients with one or more missing teeth in the posterior zone were randomly assigned to be treated with implants

  7. Indomethacin Increases Neurogenesis across Age Groups and Improves Delayed Probe Trial Difference Scores in Middle-Aged Rats

    Directory of Open Access Journals (Sweden)

    James A. McGuiness

    2017-09-01

    Full Text Available We tested whether indomethacin or rosiglitazone treatment could rejuvenate spatial ability and hippocampal neurogenesis in aging rats. Young (4 mo; n = 30, middle-aged (12 mo; n = 31, and aged (18 mo; n = 31 male Fischer 344 rats were trained and then tested in a rapid acquisition water maze task and then fed vehicle (500 μl strawberry milk, indomethacin (2.0 mg/ml, or rosiglitazone (8.0 mg/ml twice daily for the remainder of the experiment. A week after drug treatment commenced, the rats were given 3 daily BrdU (50 mg/kg injections to test whether age-related declines in neurogenesis were reversed. One week after the final BrdU injection (~2.5 weeks after the 1st water maze session, the rats were trained to a find novel hidden water maze platform location, tested on 15 min and 24 h probe trials and then killed 24 h later. During the first water maze session, young rats outperformed aged rats but all rats learned information about the hidden platform location. Middle-aged and aged rats exhibited better memory probe trial performances than young rats in the 2nd water maze session and indomethacin improved memory probe trial performances on the 2nd vs. 1st water maze session in middle-aged rats. Middle-aged rats with more new neurons had fewer phagocytic microglia and exhibited better hidden platform training trial performances on the 2nd water maze session. Regardless of age, indomethacin increased new hippocampal neuron numbers and both rosiglitazone and indomethacin increased subependymal neuroblasts/neuron densities. Taken together, our results suggest the feasibility of studying the effects of longer-term immunomodulation on age-related declines in cognition and neurogenesis.

  8. Trials

    Directory of Open Access Journals (Sweden)

    Michele Fornaro

    2010-01-01

    Full Text Available Mental Retardation (MR is a developmental disability characterized by impairments in adaptive daily life skills and difficulties in social and interpersonal functioning. Since multiple causes may contribute to MR, associated clinical pictures may vary accordingly. Nevertheless, when psychiatric disorders as Treatment Resistant Depression (TRD and/or alcohol abuse co-exist, their proper detection and management is often troublesome, essentially due to a limited vocabulary MR people could use to describe their symptoms, feelings and concerns, and the lack of reliable screening tools. Furthermore, MR people are among the most medicated subjects, with (over prescription of antidepressants and/or typical antipsychotics being the rule rather than exception. Thus, treatment resistance or even worsening of depression, constitute frequent occurrences. This report describes the case of a person with MR who failed to respond to repetitive trials of antidepressant monotherapies, finally recovering using aripiprazole to fluvoxamine augmentation upon consideration of a putative bipolar diathesis for “agitated” TRD. Although further controlled investigations are needed to assess a putative bipolar diathesis in some cases of MR associated to TRD, prudence is advised in the long-term prescription of antidepressant monotherapies in such conditions.

  9. Nonintentional behavioural responses to psi : hidden targets and hidden observers

    OpenAIRE

    Anderson, Mary-Jane Charlotte

    2012-01-01

    Psi is the phenomenon of apparently responding to or receiving information by means other than the recognised senses. Psi information may influence human behaviour, without the individual intending this or even being aware of it. This thesis seeks to investigate nonintentional behavioural responses to psi. We present five empirical studies that investigated nonintentional behavioural responses to psi information. In each study, the psi information was hidden from participants, ...

  10. Payment Platform

    DEFF Research Database (Denmark)

    Hjelholt, Morten; Damsgaard, Jan

    2012-01-01

    Payment transactions through the use of physical coins, bank notes or credit cards have for centuries been the standard formats of exchanging money. Recently online and mobile digital payment platforms has entered the stage as contenders to this position and possibly could penetrate societies...... thoroughly and substitute current payment standards in the decades to come. This paper portrays how digital payment platforms evolve in socio-technical niches and how various technological platforms aim for institutional attention in their attempt to challenge earlier platforms and standards. The paper...... applies a co-evolutionary multilevel perspective to model the interplay and processes between technology and society wherein digital payment platforms potentially will substitute other payment platforms just like the credit card negated the check. On this basis this paper formulate a multilevel conceptual...

  11. News from the Library: Knovel trial period

    CERN Multimedia

    CERN Library

    2014-01-01

    Knovel is a Web-based database integrating technical information with analytical and search tools. It is specifically aimed at the engineering community, offering validated content derived from the most trusted sources.   Knovel combines the functionalities of an e-book platform and a search engine querying a plurality of online databases. These functionalities are complemented by analytical tools that permit the extraction and manipulation of data from e-book content. Knovelʼs tools - including its interactive tables and graphs - not only help users to find information hidden in complex graphs, equations and tables quickly, but also to analyse and manipulate data as easily as sorting a spreadsheet. Using either simple keywords or full Boolean queries, Knovel searches across different data sets to find the information engineers need, however deeply it may be buried. For more information please visit why.knovel.com and the corresponding Youtube channel. A trial period of Knovel for the whol...

  12. Hidden attractors in a chaotic system with an exponential nonlinear term

    Science.gov (United States)

    Pham, V.-T.; Vaidyanathan, S.; Volos, C. K.; Jafari, S.

    2015-07-01

    Studying systems with hidden attractors is new attractive research direction because of its practical and threoretical importance. A novel system with an exponential nonlinear term, which can exhibit hidden attractors, is proposed in this work. Although new system possesses no equilibrium points, it displays rich dynamical behaviors, like chaos. By calculating Lyapunov exponents and bifurcation diagram, the dynamical behaviors of such system are discovered. Moreover, two important features of a chaotic system, the possibility of synchronization and the feasibility of the theoretical model, are also presented by introducing an adaptive synchronization scheme and designing a digital hardware platform-based emulator.

  13. On quantum algorithms for noncommutative hidden subgroups

    Energy Technology Data Exchange (ETDEWEB)

    Ettinger, M. [Los Alamos National Lab., NM (United States); Hoeyer, P. [Odense Univ. (Denmark)

    1998-12-01

    Quantum algorithms for factoring and discrete logarithm have previously been generalized to finding hidden subgroups of finite Abelian groups. This paper explores the possibility of extending this general viewpoint to finding hidden subgroups of noncommutative groups. The authors present a quantum algorithm for the special case of dihedral groups which determines the hidden subgroup in a linear number of calls to the input function. They also explore the difficulties of developing an algorithm to process the data to explicitly calculate a generating set for the subgroup. A general framework for the noncommutative hidden subgroup problem is discussed and they indicate future research directions.

  14. [Lens platform].

    Science.gov (United States)

    Łukaszewska-Smyk, Agnieszka; Kałuzny, Józef

    2010-01-01

    The lens platform defines lens structure and lens material. Evolution of lens comprises change in their shape, angulation of haptens and transition of three-piece lens into one-piece lens. The lens fall into two categories: rigid (PMMA) and soft (siliconic, acrylic, colameric). The main lens maaterials are polymers (hydrophilic and hydrophobic). The lens platform has an effect on biocompatibility, bioadhesion, stability of lens in capsule, degree of PCO evolution and sensitiveness to laser damages.

  15. Platform contents

    OpenAIRE

    Renault, Régis

    2014-01-01

    A monopoly platform hosts advertisers who compete on a market for horizontally differentiated products. These products may be either mass market products that appeal broadly to the entire consumer population or niche products that are tailored to the tastes of some particular group. Consumers search sequentially through ads incurring a surfing cost of moving to the next ad. They may click on an ad at some cost, which provides all relevant information and the opportunity to buy. The platform c...

  16. Treatment Outcome of Two Adjacent Implant-Supported Restorations with Different Implant Platform Designs in the Esthetic Region : A Five-Year Randomized Clinical Trial

    NARCIS (Netherlands)

    Van Nimwegen, Wouter G.; Raghoebar, Gerry M.; Stellingsma, Kees; Tymstra, Nynke; Vissink, Arjan; Meijer, Henny J. A.

    2015-01-01

    Purpose: The aim of this study was to evaluate the peri-implant soft and hard tissues and satisfaction in patients with two adjacent implant-supported restorations in the esthetic region, treated with two adjacent implants with a scalloped or flat platform. Materials and Methods: The randomized clin

  17. Presurgical window of opportunity trial design as a platform for testing anticancer drugs: Pros, cons and a focus on breast cancer.

    Science.gov (United States)

    Maugeri-Saccà, Marcello; Barba, Maddalena; Vici, Patrizia; Pizzuti, Laura; Sergi, Domenico; Catenaro, Teresa; Di Lauro, Luigi; Mottolese, Marcella; Santini, Daniele; Milella, Michele; De Maria, Ruggero

    2016-10-01

    The high attrition rate is a major issue in anticancer drug development. Among the alternative trial designs, presurgical window of opportunity trials envision a short course treatment in the time window between diagnostic biopsy and surgery in a moderately-sized patient population. This approach allows testing therapeutics when pre- and post-treatment tumor tissues are available for comprehensive molecular analyses. The emerging evidence may help define the ability of a given agent to modulate its target(s) and help obtain a broader picture of the molecular changes operated by the treatment. The resulting gain may outweigh the potential harms for patients in the early disease setting. Window of opportunity trials have been extensively applied to breast cancer. Overall, a wider use of these trial designs might lead to the identification of potential responders, ineffective drugs or combinations, and ultimately contribute to enhance the efficiency of the clinical developmental process. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  18. Hidden Variable Theories and Quantum Nonlocality

    Science.gov (United States)

    Boozer, A. D.

    2009-01-01

    We clarify the meaning of Bell's theorem and its implications for the construction of hidden variable theories by considering an example system consisting of two entangled spin-1/2 particles. Using this example, we present a simplified version of Bell's theorem and describe several hidden variable theories that agree with the predictions of…

  19. Estimating an Activity Driven Hidden Markov Model

    OpenAIRE

    Meyer, David A.; Shakeel, Asif

    2015-01-01

    We define a Hidden Markov Model (HMM) in which each hidden state has time-dependent $\\textit{activity levels}$ that drive transitions and emissions, and show how to estimate its parameters. Our construction is motivated by the problem of inferring human mobility on sub-daily time scales from, for example, mobile phone records.

  20. Insight: Exploring Hidden Roles in Collaborative Play

    Directory of Open Access Journals (Sweden)

    Tricia Shi

    2015-06-01

    Full Text Available This paper looks into interaction modes between players in co-located, collaborative games. In particular, hidden traitor games, in which one or more players is secretly working against the group mission, has the effect of increasing paranoia and distrust between players, so this paper looks into the opposite of a hidden traitor – a hidden benefactor. Rather than sabotaging the group mission, the hidden benefactor would help the group achieve the end goal while still having a reason to stay hidden. The paper explores what games with such a role can look like and how the role changes player interactions. Finally, the paper addresses the divide between video game and board game interaction modes; hidden roles are not common within video games, but they are of growing prevalence in board games. This fact, combined with the exploration of hidden benefactors, reveals that hidden roles is a mechanic that video games should develop into in order to match board games’ complexity of player interaction modes.

  1. Helioscope bounds on hidden sector photons

    Energy Technology Data Exchange (ETDEWEB)

    Redondo, J.

    2007-12-15

    The flux of hypothetical ''hidden photons'' from the Sun is computed under the assumption that they interact with normal matter only through kinetic mixing with the ordinary standard model photon. Requiring that the exotic luminosity is smaller than the standard photon luminosity provides limits for the mixing parameter down to {chi} hidden photon mass. Furthermore, it is pointed point out that helioscopes looking for solar axions are also sensitive to hidden photons. The recent results of the CAST collaboration are used to further constrain the mixing parameter {chi} at low masses (m{sub {gamma}}{sub '}<1 eV) where the luminosity bound is weaker. In this regime the solar hidden photon ux has a sizable contribution of longitudinally polarized hidden photons of low energy which are invisible for current helioscopes. (orig.)

  2. Heating up the Galaxy with hidden photons

    Energy Technology Data Exchange (ETDEWEB)

    Dubovsky, Sergei [Center for Cosmology and Particle Physics, Department of Physics, New York University,New York, NY, 10003 (United States); Hernández-Chifflet, Guzmán [Center for Cosmology and Particle Physics, Department of Physics, New York University,New York, NY, 10003 (United States); Instituto de Física, Facultad de Ingeniería, Universidad de la República,Montevideo, 11300 (Uruguay)

    2015-12-29

    We elaborate on the dynamics of ionized interstellar medium in the presence of hidden photon dark matter. Our main focus is the ultra-light regime, where the hidden photon mass is smaller than the plasma frequency in the Milky Way. We point out that as a result of the Galactic plasma shielding direct detection of ultra-light photons in this mass range is especially challenging. However, we demonstrate that ultra-light hidden photon dark matter provides a powerful heating source for the ionized interstellar medium. This results in a strong bound on the kinetic mixing between hidden and regular photons all the way down to the hidden photon masses of order 10{sup −20} eV.

  3. Helioscope bounds on hidden sector photons

    Energy Technology Data Exchange (ETDEWEB)

    Redondo, J.

    2007-12-15

    The flux of hypothetical ''hidden photons'' from the Sun is computed under the assumption that they interact with normal matter only through kinetic mixing with the ordinary standard model photon. Requiring that the exotic luminosity is smaller than the standard photon luminosity provides limits for the mixing parameter down to {chi} hidden photon mass. Furthermore, it is pointed point out that helioscopes looking for solar axions are also sensitive to hidden photons. The recent results of the CAST collaboration are used to further constrain the mixing parameter {chi} at low masses (m{sub {gamma}}{sub '}<1 eV) where the luminosity bound is weaker. In this regime the solar hidden photon ux has a sizable contribution of longitudinally polarized hidden photons of low energy which are invisible for current helioscopes. (orig.)

  4. Hidden Web信息获取

    Institute of Scientific and Technical Information of China (English)

    陈珂; 陈小英; 徐科

    2007-01-01

    如今Web上越来越多的信息可以通过查询接口获得,但为了获取某Hidden Web站点的页面,用户不得不键入一系列的关键词.由于没有直接指向Hidden Web页面的静态链接,当前大多搜索引擎不能发现和索引这些页面.然而,研究表明,由Hidden Web站点提供的高质量的信息对许多用户来说非常有价值.文章通过研究针对特定类型的表单,建立一个有效的Hidden Web爬虫,以便获取Hidden Web后台数据库信息.

  5. Novel Simulation Model of Non-Muscle Invasive Bladder Cancer: A Platform for a Virtual Randomized Trial of Conservative Therapy vs. Cystectomy in BCG Refractory Patients.

    Science.gov (United States)

    Patel, Sanjay; Dinh, Tuan; Noah-Vanhoucke, Joyce; Rengarajan, Badri; Mayo, Kevin; Clark, Peter E; Kamat, Ashish M; Lee, Cheryl T; Sexton, Wade J; Steinberg, Gary D

    2015-10-26

    Introduction: There have been no randomized controlled trials (RCTs) evaluating the clinical or economic benefit of mitomycin C intravesical therapy vs. radical cystectomy in patients with high-risk non-muscle invasive bladder cancer (NMIBC). We used the Archimedes computational model to simulate RCT comparing radical cystectomy versus intravesical mitomycin C (MMC) therapy to evaluate the clinical and economic outcomes for BCG-refractory NMIBC as well demonstrate the utility of computer based models to simulate a clinical trial. Methods: The Archimedes model was developed to generate a virtual population using the Surveillance Epidemiology and End Results database, other clinical trials, and expert opinions. Patients selected were diagnosed with NMIBC (virtual patients were evaluation. Progression to MIBC in the MMC treatment arm was 30% over the lifetime. Disease specific death at 5 years was 1.6% and 8.7% for the immediate cystectomy and MMC treatment arms respectively; while, overall death was 17.8% and 23.8% at 5 years. Over a 5-year period the average cost of immediate cystectomy was $64,675 vs $68,517 in the MMC arm. Conclusion: Immediate radical cystectomy after BCG failure for NMIBC has improved survival and is more cost-effective when compared to those undergoing MMC. Simulation of clinical trials using computational models similar to the Archimedes model can overcome shortcomings of real-world clinical trials and may prove useful in the face of current medical cost-conscious era.

  6. Immediately loaded platform-switched implants in the anterior mandible with fixed prostheses: a randomized, split-mouth, masked prospective trial.

    Science.gov (United States)

    Romanos, Georgios E; Malmstrom, Hans; Feng, Changyong; Ercoli, Carlo; Caton, Jack

    2014-12-01

    Platform-switched implants have been demonstrated to maintain marginal bone-level stability after immediate loading. The present study evaluated crestal bone loss and soft tissue stability around ANKYLOS plus® implants (A-implants) and Certain® PREVAIL(TM) (B-implants). Patients were identified to receive three A- or three B-implants on each side of their mandibles, with randomization. All implants were loaded immediately after their insertion and splinted with a cemented provisional prosthesis. Final prostheses were delivered 3 months after implantation. Peri-implant crestal bone loss, gingival recession, and other soft tissue changes were evaluated throughout a 2-year follow-up. A total of one hundred seven implants were placed in 18 patients. Two of the group A-implants and one group B-implant failed. At the final 24-month assessment, bone loss of at least 2 mm (mesially or distally) was recorded at 5 of the 44 surviving A-implants (11%) and 33 of the 47 B-implants (70%), a success rate of 88.63% for the A- and 29.78% for the B-implants. Significant changes in the level of the crestal bone loss around immediately loaded platform-switched dental implants seem to be related to the platform shape and size, as well as the implant-abutment connection, when abutments are not removed. © 2013 Wiley Periodicals, Inc.

  7. Hidden scale invariance of metals

    DEFF Research Database (Denmark)

    Hummel, Felix; Kresse, Georg; Dyre, Jeppe C.

    2015-01-01

    available. Hidden scale invariance is demonstrated in detail for magnesium by showing invariance of structure and dynamics. Computed melting curves of period three metals follow curves with invariance (isomorphs). The experimental structure factor of magnesium is predicted by assuming scale invariant...... of metals making the condensed part of the thermodynamic phase diagram effectively one dimensional with respect to structure and dynamics. DFT computed density scaling exponents, related to the Grüneisen parameter, are in good agreement with experimental values for the 16 elements where reliable data were......Density functional theory (DFT) calculations of 58 liquid elements at their triple point show that most metals exhibit near proportionality between the thermal fluctuations of the virial and the potential energy in the isochoric ensemble. This demonstrates a general “hidden” scale invariance...

  8. Hidden scale in quantum mechanics

    CERN Document Server

    Giri, Pulak Ranjan

    2007-01-01

    We show that the intriguing localization of a free particle wave-packet is possible due to a hidden scale present in the system. Self-adjoint extensions (SAE) is responsible for introducing this scale in quantum mechanical models through the nontrivial boundary conditions. We discuss a couple of classically scale invariant free particle systems to illustrate the issue. In this context it has been shown that a free quantum particle moving on a full line may have localized wave-packet around the origin. As a generalization, it has also been shown that particles moving on a portion of a plane or on a portion of a three dimensional space can have unusual localized wave-packet.

  9. Platform computing

    CERN Multimedia

    2002-01-01

    "Platform Computing releases first grid-enabled workload management solution for IBM eServer Intel and UNIX high performance computing clusters. This Out-of-the-box solution maximizes the performance and capability of applications on IBM HPC clusters" (1/2 page) .

  10. Hidden torsion, 3-manifolds, and homology cobordism

    CERN Document Server

    Cha, Jae Choon

    2011-01-01

    This paper continues our exploration of homology cobordism of 3-manifolds using our recent results on Cheeger-Gromov rho-invariants associated to amenable representations. We introduce a new type of torsion in 3-manifold groups we call hidden torsion, and an algebraic approximation we call local hidden torsion. We construct infinitely many hyperbolic 3-manifolds which have local hidden torsion in the transfinite lower central subgroup. By realizing Cheeger-Gromov invariants over amenable groups, we show that our hyperbolic 3-manifolds are not pairwise homology cobordant, yet remain indistinguishable by any prior known homology cobordism invariants.

  11. A survey of hidden-variables theories

    CERN Document Server

    Belinfante, F J

    1973-01-01

    A Survey of Hidden-Variables Theories is a three-part book on the hidden-variable theories, referred in this book as """"theories of the first kind"""". Part I reviews the motives in developing different types of hidden-variables theories. The quest for determinism led to theories of the first kind; the quest for theories that look like causal theories when applied to spatially separated systems that interacted in the past led to theories of the second kind. Parts II and III further describe the theories of the first kind and second kind, respectively. This book is written to make the literat

  12. Visible Effects of Invisible Hidden Valley Radiation

    CERN Document Server

    Carloni, Lisa

    2010-01-01

    Assuming there is a new gauge group in a Hidden Valley, and a new type of radiation, can we observe it through its effect on the kinematic distributions of recoiling visible particles? Specifically, what are the collider signatures of radiation in a hidden sector? We address these questions using a generic SU(N)-like Hidden Valley model that we implement in Pythia. We find that in both the e+e- and the LHC cases the kinematic distributions of the visible particles can be significantly affected by the valley radiation. Without a proper understanding of such effects, inferred masses of "communicators" and of invisible particles can be substantially off.

  13. Hidden systematics of fission channels

    Directory of Open Access Journals (Sweden)

    Schmidt Karl-Heinz

    2013-12-01

    of the fissioning system obey a hidden systematics that can be explained by the number of states in the vicinity of the outer fission barrier as a function of mass asymmetry, if the potential is constructed as the sum of the macroscopic contribution of the compound nucleus and empirically determined fragment shells. This hidden systematics also explains the transition from asymmetric to symmetric fission around 226Th and around 258Fm.

  14. Platform Constellations

    DEFF Research Database (Denmark)

    Staykova, Kalina Stefanova; Damsgaard, Jan

    2016-01-01

    messaging apps KakaoTalk and LINE, we are able to gain valuable insights about the nature of these new constructions and to capture and synthesize their main characteristics in a framework. Our results show that platform constellations possess unique innovative capabilities, which can improve users......’ acquisition and users’ engagement rates as well as unlock new sources of value creation and diversify revenue streams....

  15. Coding with partially hidden Markov models

    DEFF Research Database (Denmark)

    Forchhammer, Søren; Rissanen, J.

    1995-01-01

    Partially hidden Markov models (PHMM) are introduced. They are a variation of the hidden Markov models (HMM) combining the power of explicit conditioning on past observations and the power of using hidden states. (P)HMM may be combined with arithmetic coding for lossless data compression. A general...... 2-part coding scheme for given model order but unknown parameters based on PHMM is presented. A forward-backward reestimation of parameters with a redefined backward variable is given for these models and used for estimating the unknown parameters. Proof of convergence of this reestimation is given....... The PHMM structure and the conditions of the convergence proof allows for application of the PHMM to image coding. Relations between the PHMM and hidden Markov models (HMM) are treated. Results of coding bi-level images with the PHMM coding scheme is given. The results indicate that the PHMM can adapt...

  16. UV Photography Shows Hidden Sun Damage

    Science.gov (United States)

    ... mcat1=de12", ]; for (var c = 0; c UV photography shows hidden sun damage A UV photograph gives ... developing skin cancer and prematurely aged skin. Normal photography UV photography 18 months of age: This boy's ...

  17. Faddeev-Jackiw approach to hidden symmetries

    CERN Document Server

    Wotzasek, C

    1994-01-01

    The study of hidden symmetries within Dirac's formalism does not possess a systematic procedure due to the lack of first-class constraints to act as symmetry generators. On the other hand, in the Faddeev-Jackiw approach, gauge and reparametrization symmetries are generated by the null eigenvectors of the sympletic matrix and not by constraints, suggesting the possibility of dealing systematically with hidden symmetries through this formalism. It is shown in this paper that indeed hidden symmetries of noninvariant or gauge fixed systems are equally well described by null eigenvectors of the sympletic matrix, just as the explicit invariances. The Faddeev-Jackiw approach therefore provide a systematic algorithm for treating all sorts of symmetries in an unified way. This technique is illustrated here by the SL(2,R) Kac-Moody current algebra of the 2-D induced gravity proposed by Polyakov, which is a hidden symmetry in the canonical approach of constrained systems via Dirac's method, after conformal and reparamet...

  18. Fibroid Tumors in Women: A Hidden Epidemic?

    Science.gov (United States)

    ... Issue Past Issues Fibroid Tumors in Women: A Hidden Epidemic? Past Issues / Spring 2007 Table of Contents ... fibroids@rics.bwh.harvard.edu , or visit our Web site: www.fibroids.net . You may also write ...

  19. Hidden Regular Variation: Detection and Estimation

    CERN Document Server

    Mitra, Abhimanyu

    2010-01-01

    Hidden regular variation defines a subfamily of distributions satisfying multivariate regular variation on $\\mathbb{E} = [0, \\infty]^d \\backslash \\{(0,0, ..., 0) \\} $ and models another regular variation on the sub-cone $\\mathbb{E}^{(2)} = \\mathbb{E} \\backslash \\cup_{i=1}^d \\mathbb{L}_i$, where $\\mathbb{L}_i$ is the $i$-th axis. We extend the concept of hidden regular variation to sub-cones of $\\mathbb{E}^{(2)}$ as well. We suggest a procedure of detecting the presence of hidden regular variation, and if it exists, propose a method of estimating the limit measure exploiting its semi-parametric structure. We exhibit examples where hidden regular variation yields better estimates of probabilities of risk sets.

  20. Hidden Local Symmetry and Beyond

    CERN Document Server

    Yamawaki, Koichi

    2016-01-01

    Gerry Brown was a godfather of our hidden local symmetry (HLS) for the vector meson from the birth of the theory throughout his life. The HLS is originated from very nature of the nonlinear realization of the symmetry G based on the manifold G/H, and thus is universal to any physics based on the nonlinear realization. Here I focus on the Higgs Lagrangian of the Standard Model (SM), which is shown to be equivalent to the nonlinear sigma model based on G/H= SU(2)_L x SU(2)_R/SU(2)_V with additional symmetry, the nonlinearly realized scale symmetry. Then the SM does have a dynamical gauge boson of the SU(2)_V HLS, "SM rho meson", in addition to the Higgs as a pseudo dilaton as well as the NG bosons to be absorbed into the W and Z. Based on the recent work done with S. Matsuzaki and H. Ohki, I discuss a novel possibility that the SM rho meson acquires kinetic term by the SM dynamics itself, which then stabilizes the skyrmion dormant in the SM as a viable candidate for the dark matter, what we call "Dark SM skyrmi...

  1. Hidden local symmetry and beyond

    Science.gov (United States)

    Yamawaki, Koichi

    Gerry Brown was a godfather of our hidden local symmetry (HLS) for the vector meson from the birth of the theory throughout his life. The HLS is originated from very nature of the nonlinear realization of the symmetry G based on the manifold G/H, and thus is universal to any physics based on the nonlinear realization. Here, I focus on the Higgs Lagrangian of the Standard Model (SM), which is shown to be equivalent to the nonlinear sigma model based on G/H = SU(2)L × SU(2)R/SU(2)V with additional symmetry, the nonlinearly-realized scale symmetry. Then, the SM does have a dynamical gauge boson of the SU(2)V HLS, "SM ρ meson", in addition to the Higgs as a pseudo-dilaton as well as the NG bosons to be absorbed in to the W and Z. Based on the recent work done with Matsuzaki and Ohki, I discuss a novel possibility that the SM ρ meson acquires kinetic term by the SM dynamics itself, which then stabilizes the skyrmion dormant in the SM as a viable candidate for the dark matter, what we call "dark SM skyrmion (DSMS)".

  2. Constraining solar hidden photons using HPGe detector

    Energy Technology Data Exchange (ETDEWEB)

    Horvat, R.; Kekez, D., E-mail: Dalibor.Kekez@irb.hr; Krčmar, M.; Krečak, Z.; Ljubičić, A.

    2013-04-25

    In this Letter we report on the results of our search for photons from a U(1) gauge factor in the hidden sector of the full theory. With our experimental setup we observe the single spectrum in a HPGe detector arising as a result of the photoelectric-like absorption of hidden photons emitted from the Sun on germanium atoms inside the detector. The main ingredient of the theory used in our analysis, a severely constrained kinetic mixing from the two U(1) gauge factors and massive hidden photons, entails both photon into hidden state oscillations and a minuscule coupling of hidden photons to visible matter, of which the latter our experimental setup has been designed to observe. On a theoretical side, full account was taken of the effects of refraction and damping of photons while propagating in Sun's interior as well as in the detector. We exclude hidden photons with kinetic couplings χ>(2.2×10{sup −13}–3×10{sup −7}) in the mass region 0.2 eV≲m{sub γ{sup ′}}≲30 keV. Our constraints on the mixing parameter χ in the mass region from 20 eV up to 15 keV prove even slightly better then those obtained recently by using data from the CAST experiment, albeit still somewhat weaker than those obtained from solar and HB stars lifetime arguments.

  3. Self-management support using an Internet-linked tablet computer (the EDGE platform)-based intervention in chronic obstructive pulmonary disease: protocol for the EDGE-COPD randomised controlled trial.

    Science.gov (United States)

    Farmer, Andrew; Toms, Christy; Hardinge, Maxine; Williams, Veronika; Rutter, Heather; Tarassenko, Lionel

    2014-01-08

    The potential for telehealth-based interventions to provide remote support, education and improve self-management for long-term conditions is increasingly recognised. This trial aims to determine whether an intervention delivered through an easy-to-use tablet computer can improve the quality of life of patients with chronic obstructive pulmonary disease (COPD) by providing personalised self-management information and education. The EDGE (sElf management anD support proGrammE) for COPD is a multicentre, randomised controlled trial designed to assess the efficacy of an Internet-linked tablet computer-based intervention (the EDGE platform) in improving quality of life in patients with moderate to very severe COPD compared with usual care. Eligible patients are randomly allocated to receive the tablet computer-based intervention or usual care in a 2:1 ratio using a web-based randomisation system. Participants are recruited from respiratory outpatient clinics and pulmonary rehabilitation courses as well as from those recently discharged from hospital with a COPD-related admission and from primary care clinics. Participants allocated to the tablet computer-based intervention complete a daily symptom diary and record clinical symptoms using a Bluetooth-linked pulse oximeter. Participants allocated to receive usual care are provided with all the information given to those allocated to the intervention but without the use of the tablet computer or the facility to monitor their symptoms or physiological variables. The primary outcome of quality of life is measured using the St George's Respiratory Questionnaire for COPD patients (SGRQ-C) baseline, 6 and 12 months. Secondary outcome measures are recorded at these intervals in addition to 3 months. The Research Ethics Committee for Berkshire-South Central has provided ethical approval for the conduct of the study in the recruiting regions. The results of the study will be disseminated through peer review publications and

  4. Riboswitch Detection Using Profile Hidden Markov Models

    Directory of Open Access Journals (Sweden)

    Krishnamachari A

    2009-10-01

    Full Text Available Abstract Background Riboswitches are a type of noncoding RNA that regulate gene expression by switching from one structural conformation to another on ligand binding. The various classes of riboswitches discovered so far are differentiated by the ligand, which on binding induces a conformational switch. Every class of riboswitch is characterized by an aptamer domain, which provides the site for ligand binding, and an expression platform that undergoes conformational change on ligand binding. The sequence and structure of the aptamer domain is highly conserved in riboswitches belonging to the same class. We propose a method for fast and accurate identification of riboswitches using profile Hidden Markov Models (pHMM. Our method exploits the high degree of sequence conservation that characterizes the aptamer domain. Results Our method can detect riboswitches in genomic databases rapidly and accurately. Its sensitivity is comparable to the method based on the Covariance Model (CM. For six out of ten riboswitch classes, our method detects more than 99.5% of the candidates identified by the much slower CM method while being several hundred times faster. For three riboswitch classes, our method detects 97-99% of the candidates relative to the CM method. Our method works very well for those classes of riboswitches that are characterized by distinct and conserved sequence motifs. Conclusion Riboswitches play a crucial role in controlling the expression of several prokaryotic genes involved in metabolism and transport processes. As more and more new classes of riboswitches are being discovered, it is important to understand the patterns of their intra and inter genomic distribution. Understanding such patterns will enable us to better understand the evolutionary history of these genetic regulatory elements. However, a complete picture of the distribution pattern of riboswitches will emerge only after accurate identification of riboswitches across genomes

  5. Probing hidden sector photons through the Higgs window

    Energy Technology Data Exchange (ETDEWEB)

    Ahlers, M. [Oxford Univ. (United Kingdom). Rudolf Peierls Centre for Theoretical Physics; Jaeckel, J. [Durham Univ. (United Kingdom). Inst. for Particle Physics and Phenomenology; Redondo, J.; Ringwald, A. [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)

    2008-07-15

    We investigate the possibility that a (light) hidden sector extra photon receives its mass via spontaneous symmetry breaking of a hidden sector Higgs boson, the so-called hidden-Higgs. The hidden-photon can mix with the ordinary photon via a gauge kinetic mixing term. The hidden-Higgs can couple to the Standard Model Higgs via a renormalizable quartic term - sometimes called the Higgs Portal. We discuss the implications of this light hidden-Higgs in the context of laser polarization and light-shining-through-the-wall experiments as well as cosmological, astrophysical, and non-Newtonian force measurements. For hidden-photons receiving their mass from a hidden-Higgs we find in the small mass regime significantly stronger bounds than the bounds on massive hidden sector photons alone. (orig.)

  6. Lepton mixing from the hidden sector

    CERN Document Server

    Ludl, P O

    2015-01-01

    Experimental results indicate a possible relation between the lepton and quark mixing matrices of the form U_PMNS \\approx V_CKM^\\dagger U_X, where U_X is a matrix with special structure related to the mechanism of neutrino mass generation. We propose a framework which can realize such a relation. The main ingredients of the framework are the double seesaw mechanism, SO(10) Grand Unification and a hidden sector of theory. The latter is composed of singlets (fermions and bosons) of the GUT symmetry with masses between the GUT and Planck scale. The interactions in this sector obey certain symmetries G_hidden. We explore the conditions under which symmetries G_hidden can produce flavour structures in the visible sector. Here the key elements are the basis-fixing symmetry and mediators which communicate information about properties of the hidden sector to the visible one. The interplay of SO(10) symmetry, basis-fixing symmetry identified as Z2 x Z2 and G_hidden can lead to the required form of U_X. A different kin...

  7. Fitting Hidden Markov Models to Psychological Data

    Directory of Open Access Journals (Sweden)

    Ingmar Visser

    2002-01-01

    Full Text Available Markov models have been used extensively in psychology of learning. Applications of hidden Markov models are rare however. This is partially due to the fact that comprehensive statistics for model selection and model assessment are lacking in the psychological literature. We present model selection and model assessment statistics that are particularly useful in applying hidden Markov models in psychology. These statistics are presented and evaluated by simulation studies for a toy example. We compare AIC, BIC and related criteria and introduce a prediction error measure for assessing goodness-of-fit. In a simulation study, two methods of fitting equality constraints are compared. In two illustrative examples with experimental data we apply selection criteria, fit models with constraints and assess goodness-of-fit. First, data from a concept identification task is analyzed. Hidden Markov models provide a flexible approach to analyzing such data when compared to other modeling methods. Second, a novel application of hidden Markov models in implicit learning is presented. Hidden Markov models are used in this context to quantify knowledge that subjects express in an implicit learning task. This method of analyzing implicit learning data provides a comprehensive approach for addressing important theoretical issues in the field.

  8. Probing Hidden Sector Photons through the Higgs Window.

    OpenAIRE

    Ahlers, M.; Jaeckel, J; Redondo, J.; Ringwald, A.

    2008-01-01

    We investigate the possibility that a (light) hidden sector extra photon receives its mass via spontaneous symmetry breaking of a hidden sector Higgs boson, the so-called hidden-Higgs. The hidden-photon can mix with the ordinary photon via a gauge kinetic mixing term. The hidden-Higgs can couple to the Standard Model Higgs via a renormalizable quartic term - sometimes called the Higgs Portal. We discuss the implications of this light hidden-Higgs in the context of laser polarization and light...

  9. Supersymmetric leptogenesis and light hidden sectors

    CERN Document Server

    Weniger, Christoph

    2010-01-01

    Thermal leptogenesis and supergravity are attractive scenarios for physics beyond the standard model. However, it is well known that the super-weak interaction of the gravitino often leads to problems with primordial nucleosynthesis in the standard scenario of matter parity conserving MSSM + three right-handed neutrinos. We will present and compare two related solutions to these problems: 1) The conflict between BBN and leptogenesis can be avoided in presence of a hidden sector with light supersymmetric particles which open new decay channels for the dangerous long-lived particles. 2) If there is a condensate in the hidden sector, such additional decay channels can be alternatively opened by dynamical breaking of matter parity in the hidden sector.

  10. Clinical Utility of a Comprehensive, Whole Genome CMA Testing Platform in Pediatrics: A Prospective Randomized Controlled Trial of Simulated Patients in Physician Practices.

    Science.gov (United States)

    Peabody, John; Martin, Megan; DeMaria, Lisa; Florentino, Jhiedon; Paculdo, David; Paul, Michael; Vanzo, Rena; Wassman, E Robert; Burgon, Trever

    2016-01-01

    Developmental disorders (DD), including autism spectrum disorder (ASD) and intellectual disability (ID), are a common group of clinical manifestations caused by a variety of genetic abnormalities. Genetic testing, including chromosomal microarray (CMA), plays an important role in diagnosing these conditions, but CMA can be limited by incomplete coverage of genetic abnormalities and lack of guidance for conditions rarely seen by treating physicians. We conducted a longitudinal, randomized controlled trial investigating the impact of a higher resolution 2.8 million (MM) probe-CMA test on the quality of care delivered by practicing general pediatricians and specialists. To overcome the twin problems of finding an adequate sample size of multiple rare conditions and under/incorrect diagnoses, we used standardized simulated patients known as CPVs. Physicians, randomized into control and intervention groups, cared for the CPV pediatric patients with DD/ASD/ID. Care responses were scored against evidence-based criteria. In round one, participants could order diagnostic tests including existing CMA tests. In round two, intervention physicians could order the 2.8MM probe-CMA test. Outcome measures included overall quality of care and quality of the diagnosis and treatment plan. Physicians ordering CMA testing had 5.43% (ptest had 7.20% (ptest led to a 10.9% (ptest led to significant improvements in condition-specific interventions including an 8.3% (p = 0.04) improvement in evaluation and therapy for gross motor delays caused by Hunter syndrome, a 27.5% (p = 0.03) increase in early cognitive intervention for FOXG1-related disorder, and an 18.2% (ptest significantly improves overall quality as well as diagnosis and treatment quality for simulated cases of pediatric DD/ASD/ID patients, and delivers additional clinical utility over existing CMA tests.

  11. Testing many treatments within a single protocol over 10 years at MRC Clinical Trials Unit at UCL: Multi-arm, multi-stage platform, umbrella and basket protocols.

    Science.gov (United States)

    Parmar, Mahesh Kb; Cafferty, Fay H; Sydes, Matthew R; Choodari-Oskooei, Babak; Langley, Ruth E; Brown, Louise; Phillips, Patrick Pj; Spears, Melissa R; Rowley, Sam; Kaplan, Richard; James, Nicholas D; Maughan, Timothy; Paton, Nicholas; Royston, Patrick J

    2017-08-01

    There is real need to change how we do some of our clinical trials, as currently the testing and development process is too slow, too costly and too failure-prone - often we find that a new treatment is no better than the current standard. Much of the focus on the development and testing pathway has been in improving the design of phase I and II trials. In this paper we present examples of new methods for improving the design of phase III trials (and the necessary lead up to them) as they are the most time-consuming and expensive part of the pathway. Key to all these methods is the aim to test many treatments and/or pose many therapeutic questions within one protocol. The four principles underlying these solutions are: evaluate many primary hypotheses/treatments within the same protocol if there is a pilot/feasibility/phase II part of the process, aim to have a seamless run through to the phase III part of the process whenever possible and appropriate, conduct an adaptive trial, with the adaptations being major ones such as adding or dropping arms in situations where we are considering subgroups of a specific disease, often biomarker-defined, aim to include questions testing new treatments in all (or most) subgroups, using an adaptive approach. We present some examples of the application of these principles to particular areas, and show how they have led us to develop and launch multi-arm, multi-stage platform, umbrella and basket protocols: STAMPEDE, TRUNCATE-TB, FOCUS-4 and Add-Aspirin. There are clear challenges when embarking on such protocols. They include the need: to garner large scale collaboration bringing large parts of the research community together; to obtain significant and long-term funding; to obtain long term commitment from the key research leaders; to ensure that responsibilities (and also acclaim) are shared as widely as possible; and to have operational structures and systems which allow the implementation of such long-term adaptive protocols

  12. Hidden Markov models estimation and control

    CERN Document Server

    Elliott, Robert J; Moore, John B

    1995-01-01

    As more applications are found, interest in Hidden Markov Models continues to grow. Following comments and feedback from colleagues, students and other working with Hidden Markov Models the corrected 3rd printing of this volume contains clarifications, improvements and some new material, including results on smoothing for linear Gaussian dynamics. In Chapter 2 the derivation of the basic filters related to the Markov chain are each presented explicitly, rather than as special cases of one general filter. Furthermore, equations for smoothed estimates are given. The dynamics for the Kalman filte

  13. Hidden simplicity of gauge theory amplitudes

    Energy Technology Data Exchange (ETDEWEB)

    Drummond, J M, E-mail: drummond@lapp.in2p3.f [LAPTH, Universite de Savoie, CNRS, B.P. 110, F-74941 Annecy-le-Vieux, Cedex (France)

    2010-11-07

    These notes were given as lectures at the CERN Winter School on Supergravity, Strings and Gauge Theory 2010. We describe the structure of scattering amplitudes in gauge theories, focussing on the maximally supersymmetric theory to highlight the hidden symmetries which appear. Using the Britto, Cachzo, Feng and Witten (BCFW) recursion relations we solve the tree-level S-matrix in N=4 super Yang-Mills theory and describe how it produces a sum of invariants of a large symmetry algebra. We review amplitudes in the planar theory beyond tree level, describing the connection between amplitudes and Wilson loops, and discuss the implications of the hidden symmetries.

  14. Hidden simplicity of gauge theory amplitudes

    Science.gov (United States)

    Drummond, J. M.

    2010-11-01

    These notes were given as lectures at the CERN Winter School on Supergravity, Strings and Gauge Theory 2010. We describe the structure of scattering amplitudes in gauge theories, focussing on the maximally supersymmetric theory to highlight the hidden symmetries which appear. Using the Britto, Cachzo, Feng and Witten (BCFW) recursion relations we solve the tree-level S-matrix in \\ {N}=4 super Yang-Mills theory and describe how it produces a sum of invariants of a large symmetry algebra. We review amplitudes in the planar theory beyond tree level, describing the connection between amplitudes and Wilson loops, and discuss the implications of the hidden symmetries.

  15. Hidden neural networks: application to speech recognition

    DEFF Research Database (Denmark)

    Riis, Søren Kamaric

    1998-01-01

    We evaluate the hidden neural network HMM/NN hybrid on two speech recognition benchmark tasks; (1) task independent isolated word recognition on the Phonebook database, and (2) recognition of broad phoneme classes in continuous speech from the TIMIT database. It is shown how hidden neural networks...... (HNNs) with much fewer parameters than conventional HMMs and other hybrids can obtain comparable performance, and for the broad class task it is illustrated how the HNN can be applied as a purely transition based system, where acoustic context dependent transition probabilities are estimated by neural...

  16. Dark Radiation from a hidden U(1)

    CERN Document Server

    Vogel, Hendrik

    2015-01-01

    We discuss the impact of a hidden sector consisting of Minicharged Particles (MCPs) and massless hidden photons on the expansion history of our Universe. We present parameter scans for the amount of extra relativistic particles (Neff) and the abundance of light nuclei for fermionic MCPs with masses between ~100 keV and 10 GeV and minicharges in the range 10^(-11)-1. Current CMB and BBN data significantly constrain the available parameter space of MCPs. The shown results are a valuable indicator for future experimental searches and are presented in a flexible way so that more accurate results on Neff can be easily interpreted.

  17. Hidden Symmetries, Central Charges and All That

    CERN Document Server

    de Wit, Bernard; Wit, Bernard de; Nicolai, Hermann

    2001-01-01

    In this review we discuss hidden symmetries of toroidal compactifications of eleven-dimensional supergravity. We recall alternative versions of this theory which exhibit traces of the hidden symmetries when still retaining the massive Kaluza-Klein states. We reconsider them in the broader perspective of M-theory which incorporates a more extended variety of BPS states. We also argue for a new geometry that may underly these theories. All our arguments point towards an extension of the number of space-time coordinates beyond eleven.

  18. Hidden Subgroup States are Almost Orthogonal

    CERN Document Server

    Ettinger, M; Knill, E H; Ettinger, Mark; Hoyer, Peter; Knill, Emanuel

    1999-01-01

    It is well known that quantum computers can efficiently find a hidden subgroup $H$ of a finite Abelian group $G$. This implies that after only a polynomial (in $\\log |G|$) number of calls to the oracle function, the states corresponding to different candidate subgroups have exponentially small inner product. We show that this is true for noncommutative groups also. We present a quantum algorithm which identifies a hidden subgroup of an arbitrary finite group $G$ in only a linear (in $\\log |G|$) number of calls to the oracle function. This is exponentially better than the best classical algorithm. However our quantum algorithm requires an exponential amount of time, as in the classical case.

  19. Searching for hidden sectors in multiparticle production at the LHC

    CERN Document Server

    Sanchis-Lozano, Miguel-Angel; Moreno-Picot, Salvador

    2015-01-01

    We study the impact of a hidden sector beyond the Standard Model, e.g. a Hidden Valley model, on factorial moments and cumulants of multiplicity distributions in multiparticle production with a special emphasis on the prospects for LHC results.

  20. Entropy Rate for Hidden Markov Chains with rare transitions

    OpenAIRE

    2010-01-01

    We consider Hidden Markov Chains obtained by passing a Markov Chain with rare transitions through a noisy memoryless channel. We obtain asymptotic estimates for the entropy of the resulting Hidden Markov Chain as the transition rate is reduced to zero.

  1. The Corporate Illiterates: The Hidden Illiterates of Silicon Valley.

    Science.gov (United States)

    Chase, Sharon

    1991-01-01

    Describes the writing and business communication problems of college-educated workers in Silicon Valley. Discusses hidden illiterates in the universities and in the workplace. Offers solutions for professors and managers faced with the problem of hidden illiterates. (PRA)

  2. Hidden flows and waste processing--an analysis of illustrative futures.

    Science.gov (United States)

    Schiller, F; Raffield, T; Angus, A; Herben, M; Young, P J; Longhurst, P J; Pollard, S J T

    2010-12-14

    An existing materials flow model is adapted (using Excel and AMBER model platforms) to account for waste and hidden material flows within a domestic environment. Supported by national waste data, the implications of legislative change, domestic resource depletion and waste technology advances are explored. The revised methodology offers additional functionality for economic parameters that influence waste generation and disposal. We explore this accounting system under hypothetical future waste and resource management scenarios, illustrating the utility of the model. A sensitivity analysis confirms that imports, domestic extraction and their associated hidden flows impact mostly on waste generation. The model offers enhanced utility for policy and decision makers with regard to economic mass balance and strategic waste flows, and may promote further discussion about waste technology choice in the context of reducing carbon budgets.

  3. Design and Implementation of Domain based Semantic Hidden Web Crawler

    OpenAIRE

    Manvi; Bhatia, Komal Kumar; Dixit, Ashutosh

    2015-01-01

    Web is a wide term which mainly consists of surface web and hidden web. One can easily access the surface web using traditional web crawlers, but they are not able to crawl the hidden portion of the web. These traditional crawlers retrieve contents from web pages, which are linked by hyperlinks ignoring the information hidden behind form pages, which cannot be extracted using simple hyperlink structure. Thus, they ignore large amount of data hidden behind search forms. This paper emphasizes o...

  4. Variational Hidden Conditional Random Fields with Coupled Dirichlet Process Mixtures

    NARCIS (Netherlands)

    Bousmalis, K.; Zafeiriou, S.; Morency, L.P.; Pantic, Maja; Ghahramani, Z.

    2013-01-01

    Hidden Conditional Random Fields (HCRFs) are discriminative latent variable models which have been shown to successfully learn the hidden structure of a given classification problem. An infinite HCRF is an HCRF with a countably infinite number of hidden states, which rids us not only of the necessit

  5. Perceptual consequences of "hidden" hearing loss.

    Science.gov (United States)

    Plack, Christopher J; Barker, Daphne; Prendergast, Garreth

    2014-09-09

    Dramatic results from recent animal experiments show that noise exposure can cause a selective loss of high-threshold auditory nerve fibers without affecting absolute sensitivity permanently. This cochlear neuropathy has been described as hidden hearing loss, as it is not thought to be detectable using standard measures of audiometric threshold. It is possible that hidden hearing loss is a common condition in humans and may underlie some of the perceptual deficits experienced by people with clinically normal hearing. There is some evidence that a history of noise exposure is associated with difficulties in speech discrimination and temporal processing, even in the absence of any audiometric loss. There is also evidence that the tinnitus experienced by listeners with clinically normal hearing is associated with cochlear neuropathy, as measured using Wave I of the auditory brainstem response. To date, however, there has been no direct link made between noise exposure, cochlear neuropathy, and perceptual difficulties. Animal experiments also reveal that the aging process itself, in the absence of significant noise exposure, is associated with loss of auditory nerve fibers. Evidence from human temporal bone studies and auditory brainstem response measures suggests that this form of hidden loss is common in humans and may have perceptual consequences, in particular, regarding the coding of the temporal aspects of sounds. Hidden hearing loss is potentially a major health issue, and investigations are ongoing to identify the causes and consequences of this troubling condition.

  6. The structural strength of glass: hidden damage

    NARCIS (Netherlands)

    Veer, F.A.; Rodichev, Y.M.

    2011-01-01

    We discuss “hidden damage” of glass by the rolling process, which results in heterogeneous distribution of microcracks on the edge surface of glass element, which are the fracture source deteriorating glass element strength. It is shown that removal of this damage on the edges of glass elements

  7. Discovering Hidden Treasures with GPS Technology

    Science.gov (United States)

    Nagel, Paul; Palmer, Roger

    2014-01-01

    "I found it!" Addison proudly proclaimed, as she used an iPhone and Global Positioning System (GPS) software to find the hidden geocache along the riverbank. Others in Lisa Bostick's fourth grade class were jealous, but there would be other geocaches to find. With the excitement of movies like "Pirates of the Caribbean" and…

  8. Hidden Markov Models for Human Genes

    DEFF Research Database (Denmark)

    Baldi, Pierre; Brunak, Søren; Chauvin, Yves

    1997-01-01

    We analyse the sequential structure of human genomic DNA by hidden Markov models. We apply models of widely different design: conventional left-right constructs and models with a built-in periodic architecture. The models are trained on segments of DNA sequences extracted such that they cover...

  9. Dermatologic hazards from hidden contacts with penicillin

    Energy Technology Data Exchange (ETDEWEB)

    Boonk, W.J.

    1981-01-01

    The unbridled use of penicillin after its discovery by Fleming has resulted in possible hazards to human health due to traces of the drug being present in food and other hidden sources. These hazards may include toxic effects, hypersensitivity reactions and possibly a raising of the frequency and duration of allergy to penicillin.

  10. The structural strength of glass: hidden damage

    NARCIS (Netherlands)

    Veer, F.A.; Rodichev, Y.M.

    2011-01-01

    We discuss “hidden damage” of glass by the rolling process, which results in heterogeneous distribution of microcracks on the edge surface of glass element, which are the fracture source deteriorating glass element strength. It is shown that removal of this damage on the edges of glass elements incr

  11. Computerized Testing: The Hidden Figures Test.

    Science.gov (United States)

    Jacobs, Ronald L.; And Others

    1985-01-01

    This study adapted the Hidden Figures Test for use on PLATO and determined the reliability of the computerized version compared to the paper and pencil version. Results indicate the test was successfully adapted with some modifications, and it was judged reliable although it may be measuring additional constructs. (MBR)

  12. Towards gauge unified, supersymmetric hidden strong dynamics

    CERN Document Server

    Chiang, Cheng-Wei; Ye, Fang

    2016-01-01

    We consider a class of models with extra complex scalars that are charged under both the Standard Model and a hidden strongly coupled $SU(N)_H$ gauge sector, and discuss the scenarios where the new scalars are identified as the messenger fields that mediate the spontaneously broken supersymmetries from the hidden sector to the visible sector. The new scalars are embedded into 5-plets and 10-plets of an $SU(5)_V$ gauge group that potentially unifies the Standard Model gauge groups. They also form a tower of bound states via hidden strong dynamics around the TeV scale. The Higgs bosons remain as elementary particles. Quadratically divergent contributions to the Higgs mass from the Standard Model fermions are canceled by the new scalar contributions to alleviate the fine-tuning problem. We also discuss a supersymmetrized version of this class of models, consisting of the minimal supersymmetric Standard Model plus extra chiral multiplets where the new scalars reside. Due to the hidden strong force, the new low-en...

  13. Hidden Costs and Challenges of Servitization

    DEFF Research Database (Denmark)

    Yang, Yifan; Slepniov, Dmitrij

    of these labels, the potential benefits of servitization are often overshadowed by costs associated with it. By using the cases of Chinese and Danish manufacturing firms, this study takes a closer look at possible hidden costs of servitization and contributes to our understanding of servitization performance...

  14. Quantum Discord, CHSH Inequality and Hidden Variables -- Critical reassessment of hidden-variables models

    CERN Document Server

    Fujikawa, Kazuo

    2013-01-01

    Hidden-variables models are critically reassessed. It is first examined if the quantum discord is classically described by the hidden-variable model of Bell in the Hilbert space with $d=2$. The criterion of vanishing quantum discord is related to the notion of reduction and, surprisingly, the hidden-variable model in $d=2$, which has been believed to be consistent so far, is in fact inconsistent and excluded by the analysis of conditional measurement and reduction. The description of the full contents of quantum discord by the deterministic hidden-variables models is not possible. We also re-examine CHSH inequality. It is shown that the well-known prediction of CHSH inequality $|B|\\leq 2$ for the CHSH operator $B$ introduced by Cirel'son is not unique. This non-uniqueness arises from the failure of linearity condition in the non-contextual hidden-variables model in $d=4$ used by Bell and CHSH, in agreement with Gleason's theorem which excludes $d=4$ non-contextual hidden-variables models. If one imposes the l...

  15. Addition of docetaxel, zoledronic acid, or both to first-line long-term hormone therapy in prostate cancer (STAMPEDE): survival results from an adaptive, multiarm, multistage, platform randomised controlled trial

    Science.gov (United States)

    James, Nicholas D; Sydes, Matthew R; Clarke, Noel W; Mason, Malcolm D; Dearnaley, David P; Spears, Melissa R; Ritchie, Alastair W S; Parker, Christopher C; Russell, J Martin; Attard, Gerhardt; de Bono, Johann; Cross, William; Jones, Rob J; Thalmann, George; Amos, Claire; Matheson, David; Millman, Robin; Alzouebi, Mymoona; Beesley, Sharon; Birtle, Alison J; Brock, Susannah; Cathomas, Richard; Chakraborti, Prabir; Chowdhury, Simon; Cook, Audrey; Elliott, Tony; Gale, Joanna; Gibbs, Stephanie; Graham, John D; Hetherington, John; Hughes, Robert; Laing, Robert; McKinna, Fiona; McLaren, Duncan B; O'Sullivan, Joe M; Parikh, Omi; Peedell, Clive; Protheroe, Andrew; Robinson, Angus J; Srihari, Narayanan; Srinivasan, Rajaguru; Staffurth, John; Sundar, Santhanam; Tolan, Shaun; Tsang, David; Wagstaff, John; Parmar, Mahesh K B

    2016-01-01

    Summary Background Long-term hormone therapy has been the standard of care for advanced prostate cancer since the 1940s. STAMPEDE is a randomised controlled trial using a multiarm, multistage platform design. It recruits men with high-risk, locally advanced, metastatic or recurrent prostate cancer who are starting first-line long-term hormone therapy. We report primary survival results for three research comparisons testing the addition of zoledronic acid, docetaxel, or their combination to standard of care versus standard of care alone. Methods Standard of care was hormone therapy for at least 2 years; radiotherapy was encouraged for men with N0M0 disease to November, 2011, then mandated; radiotherapy was optional for men with node-positive non-metastatic (N+M0) disease. Stratified randomisation (via minimisation) allocated men 2:1:1:1 to standard of care only (SOC-only; control), standard of care plus zoledronic acid (SOC + ZA), standard of care plus docetaxel (SOC + Doc), or standard of care with both zoledronic acid and docetaxel (SOC + ZA + Doc). Zoledronic acid (4 mg) was given for six 3-weekly cycles, then 4-weekly until 2 years, and docetaxel (75 mg/m2) for six 3-weekly cycles with prednisolone 10 mg daily. There was no blinding to treatment allocation. The primary outcome measure was overall survival. Pairwise comparisons of research versus control had 90% power at 2·5% one-sided α for hazard ratio (HR) 0·75, requiring roughly 400 control arm deaths. Statistical analyses were undertaken with standard log-rank-type methods for time-to-event data, with hazard ratios (HRs) and 95% CIs derived from adjusted Cox models. This trial is registered at ClinicalTrials.gov (NCT00268476) and ControlledTrials.com (ISRCTN78818544). Findings 2962 men were randomly assigned to four groups between Oct 5, 2005, and March 31, 2013. Median age was 65 years (IQR 60–71). 1817 (61%) men had M+ disease, 448 (15%) had N+/X M0, and 697 (24%) had N0M0. 165 (6

  16. The hidden X suture: a technical note on a novel suture technique for alveolar ridge preservation

    Science.gov (United States)

    2016-01-01

    Purpose The present study investigated the impact of 2 different suture techniques, the conventional crossed mattress suture (X suture) and the novel hidden X suture, for alveolar ridge preservation (ARP) with an open healing approach. Methods This study was a prospective randomized controlled clinical trial. Fourteen patients requiring extraction of the maxillary or mandibular posterior teeth were enrolled and allocated into 2 groups. After extraction, demineralized bovine bone matrix mixed with 10% collagen (DBBM-C) was grafted and the socket was covered by porcine collagen membrane in a double-layer fashion. No attempt to obtain primary closure was made. The hidden X suture and conventional X suture techniques were performed in the test and control groups, respectively. Cone-beam computed tomographic (CBCT) images were taken immediately after the graft procedure and before implant surgery 4 months later. Additionally, the change in the mucogingival junction (MGJ) position was measured and was compared after extraction, after suturing, and 4 months after the operation. Results All sites healed without any complications. Clinical evaluations showed that the MGJ line shifted to the lingual side immediately after the application of the X suture by 1.56±0.90 mm in the control group, while the application of the hidden X suture rather pushed the MGJ line slightly to the buccal side by 0.25±0.66 mm. It was demonstrated that the amount of keratinized tissue (KT) preserved on the buccal side was significantly greater in the hidden X suture group 4 months after the procedure (Pclinical and radiographic verification of the efficacy of the hidden X suture in preserving the width of KT and the dimensions of the alveolar ridge after ARP. PMID:28050319

  17. Hidden penis release: adjunctive suprapubic lipectomy.

    Science.gov (United States)

    Horton, C E; Vorstman, B; Teasley, D; Winslow, B

    1987-08-01

    We believe the hidden penis may be caused and concealed by a prominent suprapubic fat pad in addition to the restrictive fibrous bands of the dartos fascia fixing the shaft of the penis proximally while loose skin folds prolapse distally over the phallus. A penis of inadequate length or appearance may affect body image. Patients with this problem often require psychological support. Hidden penis may be distinguished from micropenis by palpating adequate corpora and showing a stretched penile length within 2 SD of normal. Excision of suprapubic fat with sectioning of the tethering dartos bands will release and increase the length of the penis. Suprapubic fat pad resection may also be helpful to elongate a short penis in cases of adult microphallus, or after partial penectomy because of trauma or cancer. Circumcision is contraindicated.

  18. Laser experiments explore the hidden sector

    CERN Document Server

    Ahlers, M; Jaeckel, J; Redondo, J; Ringwald, A

    2007-01-01

    Recently, the laser experiments BMV and GammeV, searching for light shining through walls, have published data and calculated new limits on the allowed masses and couplings for axion-like particles. In this note we point out that these experiments can serve to constrain a much wider variety of hidden-sector particles such as, e.g., minicharged particles and hidden-sector photons. The new experiments improve the existing bounds from the older BFRT experiment by a factor of two. Moreover, we use the new PVLAS constraints on a possible rotation and ellipticity of light after it has passed through a strong magnetic field to constrain pure minicharged particle models. For masses <~0.05 eV, the charge is now restricted to be less than (3-4)x10^(-7) times the electron electric charge. This is the best laboratory bound and comparable to bounds inferred from the energy spectrum of the cosmic microwave background.

  19. Extended abstract of a hidden agenda

    Energy Technology Data Exchange (ETDEWEB)

    Goguen, J.; Malcolm, G. [Oxford Univ. (United Kingdom)

    1996-12-31

    The initial goal of our hidden research programme was both straightforward and ambitious: give a semantics for software engineering, and in particular for the object paradigm, supporting correctness proofs that are as simple and mechanical as possible. This emphasizes proofs rather than models, and thus suggests an equational approach, rather than one based on higher order logic, denotational semantics, or any kind of model, because equational proofs achieve maximal simplicity and mechanization, and yet are fully expressive. We introduce powerful coinduction techniques for proving behavioral properties of complex systems. We make the no doubt outrageous claim that our hidden approach gives simpler proofs than other formalisms; this is because we exploit algebraic structure that most other approaches discard.

  20. Hidden geometric correlations in real multiplex networks

    Science.gov (United States)

    Kleineberg, Kaj-Kolja; Boguñá, Marián; Ángeles Serrano, M.; Papadopoulos, Fragkiskos

    2016-11-01

    Real networks often form interacting parts of larger and more complex systems. Examples can be found in different domains, ranging from the Internet to structural and functional brain networks. Here, we show that these multiplex systems are not random combinations of single network layers. Instead, they are organized in specific ways dictated by hidden geometric correlations between the layers. We find that these correlations are significant in different real multiplexes, and form a key framework for answering many important questions. Specifically, we show that these geometric correlations facilitate the definition and detection of multidimensional communities, which are sets of nodes that are simultaneously similar in multiple layers. They also enable accurate trans-layer link prediction, meaning that connections in one layer can be predicted by observing the hidden geometric space of another layer. And they allow efficient targeted navigation in the multilayer system using only local knowledge, outperforming navigation in the single layers only if the geometric correlations are sufficiently strong.

  1. Binary hidden Markov models and varieties

    CERN Document Server

    Critch, Andrew J

    2012-01-01

    The technological applications of hidden Markov models have been extremely diverse and successful, including natural language processing, gesture recognition, gene sequencing, and Kalman filtering of physical measurements. HMMs are highly non-linear statistical models, and just as linear models are amenable to linear algebraic techniques, non-linear models are amenable to commutative algebra and algebraic geometry. This paper examines closely those HMMs in which all the random variables, called nodes, are binary. Its main contributions are (1) minimal defining equations for the 4-node model, comprising 21 quadrics and 29 cubics, which were computed using Gr\\"obner bases in the cumulant coordinates of Sturmfels and Zwiernik, and (2) a birational parametrization for every binary HMM, with an explicit inverse for recovering the hidden parameters in terms of observables. The new model parameters in (2) are hence rationally identifiable in the sense of Sullivant, Garcia-Puente, and Spielvogel, and each model's Zar...

  2. Product Platform Performance

    DEFF Research Database (Denmark)

    Munk, Lone

    engaging in platform-based product development. Similarly platform assessment criteria lack empirical verification regarding relevance and sufficiency. The thesis focuses on • the process of identifying and estimating internal effects, • verification of performance of product platforms, (i...... to support this understanding. Finally a categorisation of different approaches to platform-based product development is introduced, based on the companies from the industrial study.......The aim of this research is to improve understanding of platform-based product development by studying platform performance in relation to internal effects in companies. Platform-based product development makes it possible to deliver product variety and at the same time reduce the needed resources...

  3. The Hidden Gifts of Quiet Kids

    Science.gov (United States)

    Trierweiler, Hannah

    2006-01-01

    The author relates that she was an introvert child. It has always taken her time and energy to find her place in a group. As a grown-up, she still needed quiet time to regroup during a busy day. In this article, the author presents an interview with Marti Olsen Laney, author of "The Hidden Gifts of the Introverted Child." During the interview,…

  4. Finite State Transducers Approximating Hidden Markov Models

    CERN Document Server

    Kempe, A

    1999-01-01

    This paper describes the conversion of a Hidden Markov Model into a sequential transducer that closely approximates the behavior of the stochastic model. This transformation is especially advantageous for part-of-speech tagging because the resulting transducer can be composed with other transducers that encode correction rules for the most frequent tagging errors. The speed of tagging is also improved. The described methods have been implemented and successfully tested on six languages.

  5. Hidden symmetries in dilaton-axion gravity

    CERN Document Server

    Kechkin, O V

    1996-01-01

    Four--dimensional Einstein--Maxwell--dilaton--axion system restricted to space--times with one non--null Killing symmetry is formulated as the three--dimensional gravity coupled sigma--model. Several alternative representations are discussed and the associated hidden symmetries are revealed. The action of target space isometries on the initial set of (non--dualized ) variables is found. New mulicenter solutions are obtained via generating technique based on the formulation in terms of the non--dualized variables.

  6. Caldera rim collapse: A hidden volcanic hazard

    OpenAIRE

    Merle, Olivier; Michon, Laurent; Bachèlery, Patrick

    2008-01-01

    International audience; Following the emblematic flank collapse of Mount St Helens in 1981, numerous models of flank sliding have been proposed. These models have allowed to largely improve the understanding of mechanisms involved in such landslides, which represent a tremendous risk for populations living around volcanoes. In this article, a new mode of landslide formation, related to buried calderas, is described. The model emphasizes the paramount importance of the hidden ring fault that, ...

  7. Killing and letting die: hidden value assumptions.

    Science.gov (United States)

    Atkinson, G

    1983-01-01

    In this paper I argue for several related theses: first, that the distinction between killing and letting die, as it is drawn by ordinary persons in ordinary contexts, is more complex than is generally understood; second, that the key feature of this complexity lies in the presence of a hidden normative component in what appears to be a straightforwardly descriptive distinction; and, third, that this complexity renders the killing/letting die distinction an inadequate and hazardous guide for moral reasoning.

  8. Online Learning in Discrete Hidden Markov Models

    OpenAIRE

    Alamino, Roberto C.; Caticha, Nestor

    2007-01-01

    We present and analyse three online algorithms for learning in discrete Hidden Markov Models (HMMs) and compare them with the Baldi-Chauvin Algorithm. Using the Kullback-Leibler divergence as a measure of generalisation error we draw learning curves in simplified situations. The performance for learning drifting concepts of one of the presented algorithms is analysed and compared with the Baldi-Chauvin algorithm in the same situations. A brief discussion about learning and symmetry breaking b...

  9. Lepton mixing from the hidden sector

    Science.gov (United States)

    Ludl, P. O.; Smirnov, A. Yu.

    2015-10-01

    Experimental results indicate a possible relation between the lepton and quark mixing matrices of the form UPMNS≈VCKM†UX , where UX is a matrix with special structure related to the mechanism of neutrino mass generation. We propose a framework which can realize such a relation. The main ingredients of the framework are the double seesaw mechanism, SO(10) grand unification and a hidden sector of theory. The latter is composed of singlets (fermions and bosons) of the grand unified theory (GUT) symmetry with masses between the GUT and Planck scale. The interactions in this sector obey certain symmetries Ghidden. We explore the conditions under which symmetries Ghidden can produce flavor structures in the visible sector. Here the key elements are the basis-fixing symmetry and mediators which communicate information about properties of the hidden sector to the visible one. The interplay of SO(10) symmetry, basis-fixing symmetry identified as Z2×Z2 and Ghidden can lead to the required form of UX. A different kind of new physics is responsible for generation of the CKM mixing. We present the simplest realizations of the framework which differ by nature of the mediators and by symmetries of the hidden sector.

  10. Otoendoscopic treatment of hidden lesions in otomastoiditis

    Institute of Scientific and Technical Information of China (English)

    LIU Yang; SUN Jian-jun; LIN Yong-sheng; ZHAO Dan-heng; ZHAO Jing; LEI Fei

    2010-01-01

    Background Surgical treatments for chronic suppurative and cholesteatoma otitis media have been discussed for several decades, but recurrences still occur because of the complex dissection required and hidden lesions associated with otomastoiditis. This study investigated the technology and strategy behind the use of otoendoscopic-assisted otosurgery.Methods We reported on hidden lesions in 32 ears of patients with otomastoiditis between November 2006 and January 2009. All the patients were treated with the aid of an otoendoscope. The advantages of otoendoscopy, including multi-angle light scattering, aperture illumination, and magnification of the local operative field, were utilized in otologic microsurgery, and otoendoscopic operative techniques were introduced for operative sites such as the epitympanum, aditus of the antrum, facial recess, sinus tympani and the mastoid tip.Results All patients were followed up from 3 months to 2 years after surgery. All patients recovered well within 3 months following surgery, except for one case of epithelialization of the mastoid cavity occurring 6 months after surgery for cholesteatoma on the cerebellar surface and another case with Bezold's abscess, hyperplastic granulation tissue developed at the antrum.Conclusions Otoendoscopy can overcome the technical deficiency of rectilinearity of the visual axis associated with otomicroscopic illumination, which presents a problem when dealing with otomastoiditis lesions in hidden areas. This technique allows such lesions within the complex three-dimensional structure to be visualized and cleaned. Otoendoscopy thus has significant potential for improving the quality of surgery and reducing the risk of postoperative recurrence.

  11. Dark matter in the hidden gauge theory

    CERN Document Server

    Yamanaka, Nodoka; Gongyo, Shinya; Iida, Hideaki

    2014-01-01

    The cosmological scenario of the dark matter generated in the hidden gauge theory based on the grand unification is discussed. It is found that the stability of the dark matter halo of our Galaxy and the cosmic ray observation constrain, respectively, the dark matter mass and the unification scale between the standard model and the hidden gauge theory sectors. To obtain a phenomenologically consistent thermal evolution, the entropy of the standard model sector needs to be increased. We therefore propose a scenario where the mini-inflation is induced from the potential coupled to the Standard model sector, in particular the Higgs sector. This scenario makes consistent the current dark matter density as well as the baryon-to-photon ratio for the case of pion dark matter. For the glueball or heavy pion of hidden gauge theory, an additional mini-inflation in the standard model sector before the leptogenesis is required. We also propose the possibility to confirm this scenario by known prospective experimental app...

  12. Discovering Hidden Networks in On-line Social Networks

    Directory of Open Access Journals (Sweden)

    Pooja Wadhwa

    2014-04-01

    Full Text Available Rapid developments in information technology and Web 2.0 have provided a platform for the evolution of terrorist organizations, extremists from a traditional pyramidal structure to a technology enabled networked structure. Growing presence of these subversive groups on social networking sites has emerged as one of the prominent threats to the society, governments and law enforcement agencies across the world. Identifying messages relevant to the domain of security can serve as a stepping stone in criminal network analysis. In this paper, we deploy a rule based approach for classifying messages in Twitter which can also successfully reveal overlapping clusters. The approach incorporates dictionaries of enriched themes where each theme is categorized by semantically related words. The message is vectorized according to the security dictionaries and is termed as ‘Security Vector’. The documents are classified in categories on the basis of security associations. Further, the approach can also be used along the temporal dimension for classifying messages into topics and rank the most prominent topics of conversation at a particular instance of time. We further employ social network analysis techniques to visualize the hidden network at a particular time. Some of the results of our approach obtained through experiment with information network of Twitter are also discussed.

  13. Intermittent swim stress causes Morris water maze performance deficits in a massed-learning trial procedure that are exacerbated by reboxetine.

    Science.gov (United States)

    Warner, Timothy A; Stafford, Nathaniel P; Rompala, Gregory R; Van Hoogenstyn, Andrew J; Elgert, Emily; Drugan, Robert C

    2013-11-15

    Various animal models of depression have been used to seek a greater understanding of stress-related disorders. However, there is still a great need for research in this area, as many unanswered questions remain. Therefore, we sought to employ a novel animal model of depression known as intermittent swim stress (ISS). In this model, the animal experiences 100 trials of cold water swim stress. ISS has already shown subsequent immobility in the forced swim test (FST), deficits in instrumental and spatial (spaced-trial procedure), and responsiveness to norepinephrine. We are now examining how this will translate in the Morris water maze for rats in a massed-learning trial procedure, and further assessing ISS sensitivity toward norepinephrine selective anti-depressant drugs. The results indicated no difference in cued learning when the platform was visible in the water maze, but a hidden platform task revealed poorer spatial learning for ISS-exposed rats versus controls. In terms of spatial memory, there was a notable ISS-induced deficit 1h after the learning trials, regardless of performance on the previous platform task. Interestingly, the administration of reboxetine interfered with the spatial learning and memory trials for both ISS and CC groups. As a result, ISS exposure compromised spatial learning and memory in the Morris water maze, and norepinephrine does not appear to be a mediator of this deficit. The results demonstrate a key difference in the effects of reboxetine in a massed- vs. spaced-learning trial procedure in the Morris water maze following ISS exposure.

  14. Product Platform Modeling

    DEFF Research Database (Denmark)

    Pedersen, Rasmus

    on the notion that reuse and encapsulation of platform elements are fundamental characteristics of a product platform. Reuse covers the desire to reuse and share certain assets across a family of products and/or across generations of products. Product design solutions and principles are often regarded...... as important assets in a product platform, yet activities, working patterns, processes and knowledge can also be reused in a platform approach. Encapsulation is seen as a process in which the different elements of a platform are grouped into well defined and self-contained units which are decoupled from each......This PhD thesis has the title Product Platform Modelling. The thesis is about product platforms and visual product platform modelling. Product platforms have gained an increasing attention in industry and academia in the past decade. The reasons are many, yet the increasing globalisation...

  15. Hidden laser communications through matter. An application of meV-scale hidden photons

    Energy Technology Data Exchange (ETDEWEB)

    Jaeckel, Joerg [Durham Univ. (United Kingdom). Inst. for Particle Physics and Phenomenology; Redondo, Javier; Ringwald, Andreas [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)

    2009-04-15

    Currently, there are a number of light-shining-through-walls experiments searching for hidden photons - light, sub-eV-scale, abelian gauge bosons beyond the standard model which mix kinetically with the standard photon. We show that in the case that one of these experiments finds evidence for hidden photons, laser communications through matter, using methods from free-space optics, can be realized in the very near future, with a channel capacity of more than 1 bit per second, for a distance up to the Earth's diameter. (orig.)

  16. Microwave background constraints on mixing of photons with hidden photons

    Energy Technology Data Exchange (ETDEWEB)

    Mirizzi, Alessandro [Max-Planck-Institut fuer Physik, Muenchen (Germany); Redondo, Javier [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Sigl, Guenter [Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik

    2008-12-15

    Various extensions of the Standard Model predict the existence of hidden photons kinetically mixing with the ordinary photon. This mixing leads to oscillations between photons and hidden photons, analogous to the observed oscillations between different neutrino flavors. In this context, we derive new bounds on the photon-hidden photon mixing parameters using the high precision cosmic microwave background spectral data collected by the Far Infrared Absolute Spectrophotometer instrument on board of the Cosmic Background Explorer. Requiring the distortions of the CMB induced by the photon-hidden photon mixing to be smaller than experimental upper limits, this leads to a bound on the mixing angle {chi}{sub 0} hidden photon masses between 10{sup -14} eV and 10{sup -7} eV. This low-mass and low-mixing region of the hidden photon parameter space was previously unconstrained. (orig.)

  17. VISIBLE COSTS AND HIDDEN COSTS IN THE BAKING INDUSTRY

    Directory of Open Access Journals (Sweden)

    Criveanu Maria

    2013-04-01

    Full Text Available Hidden costs are present in the activity of any company, hardly identified in the traditional administrative accounting. The high levels of the hidden costs and their unknown presence have serious consequences on the decisions made by the managers. This paper aims at presenting some aspects related to the hidden costs that occur in the activity of the companies in the baking industry and the possibilities to reduce their level.

  18. Hidden History: A Mobile Application for Discovering Surrounding Landscapes

    OpenAIRE

    2016-01-01

    This thesis work describes the design, development and evaluation of a mobile application called Hidden History. This application lets users discover and explore three types of landscapes (Historic, Scenic and Cultural) using three different modes of discovery (Route, Explore and Tour). Before designing Hidden History, the feature set of other applications that help users explore surrounding landscapes were identified and analyzed. Hidden History was then designed to implement the best fea...

  19. HIDDEN WEB EXTRACTOR DYNAMIC WAY TO UNCOVER THE DEEP WEB

    OpenAIRE

    DR. ANURADHA; BABITA AHUJA

    2012-01-01

    In this era of digital tsunami of information on the web, everyone is completely dependent on the WWW for information retrieval. This has posed a challenging problem in extracting relevant data. Traditional web crawlers focus only on the surface web while the deep web keeps expanding behind the scene. The web databases are hidden behind the query interfaces. In this paper, we propose a Hidden Web Extractor (HWE) that can automatically discover and download data from the Hidden Web databases. ...

  20. ADAPTIVE LEARNING OF HIDDEN MARKOV MODELS FOR EMOTIONAL SPEECH

    Directory of Open Access Journals (Sweden)

    A. V. Tkachenia

    2014-01-01

    Full Text Available An on-line unsupervised algorithm for estimating the hidden Markov models (HMM parame-ters is presented. The problem of hidden Markov models adaptation to emotional speech is solved. To increase the reliability of estimated HMM parameters, a mechanism of forgetting and updating is proposed. A functional block diagram of the hidden Markov models adaptation algorithm is also provided with obtained results, which improve the efficiency of emotional speech recognition.

  1. Hidden Photons in Aharonov-Bohm-Type Experiments

    OpenAIRE

    Arias, Paola; Diaz, Christian; Diaz, Marco Aurelio; Jaeckel, Joerg; Koch, Benjamin; Redondo, Javier

    2016-01-01

    We discuss the Aharonov-Bohm effect in the presence of hidden photons kinetically mixed with the ordinary electromagnetic photons. The hidden photon field causes a slight phase shift in the observable interference pattern. It is then shown how the limited sensitivity of this experiment can be largely improved. The key observation is that the hidden photon field causes a leakage of the ordinary magnetic field into the supposedly field-free region. The direct measurement of this magnetic field ...

  2. VISIBLE COSTS AND HIDDEN COSTS IN THE BAKING INDUSTRY

    OpenAIRE

    Criveanu Maria; Ţaicu Marian

    2013-01-01

    Hidden costs are present in the activity of any company, hardly identified in the traditional administrative accounting. The high levels of the hidden costs and their unknown presence have serious consequences on the decisions made by the managers. This paper aims at presenting some aspects related to the hidden costs that occur in the activity of the companies in the baking industry and the possibilities to reduce their level.

  3. A hidden Ising model for ChIP-chip data analysis

    KAUST Repository

    Mo, Q.

    2010-01-28

    Motivation: Chromatin immunoprecipitation (ChIP) coupled with tiling microarray (chip) experiments have been used in a wide range of biological studies such as identification of transcription factor binding sites and investigation of DNA methylation and histone modification. Hidden Markov models are widely used to model the spatial dependency of ChIP-chip data. However, parameter estimation for these models is typically either heuristic or suboptimal, leading to inconsistencies in their applications. To overcome this limitation and to develop an efficient software, we propose a hidden ferromagnetic Ising model for ChIP-chip data analysis. Results: We have developed a simple, but powerful Bayesian hierarchical model for ChIP-chip data via a hidden Ising model. Metropolis within Gibbs sampling algorithm is used to simulate from the posterior distribution of the model parameters. The proposed model naturally incorporates the spatial dependency of the data, and can be used to analyze data with various genomic resolutions and sample sizes. We illustrate the method using three publicly available datasets and various simulated datasets, and compare it with three closely related methods, namely TileMap HMM, tileHMM and BAC. We find that our method performs as well as TileMap HMM and BAC for the high-resolution data from Affymetrix platform, but significantly outperforms the other three methods for the low-resolution data from Agilent platform. Compared with the BAC method which also involves MCMC simulations, our method is computationally much more efficient. Availability: A software called iChip is freely available at http://www.bioconductor.org/. Contact: moq@mskcc.org. © The Author 2010. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org.

  4. Reliability of plantar pressure platforms.

    Science.gov (United States)

    Hafer, Jocelyn F; Lenhoff, Mark W; Song, Jinsup; Jordan, Joanne M; Hannan, Marian T; Hillstrom, Howard J

    2013-07-01

    Plantar pressure measurement is common practice in many research and clinical protocols. While the accuracy of some plantar pressure measuring devices and methods for ensuring consistency in data collection on plantar pressure measuring devices have been reported, the reliability of different devices when testing the same individuals is not known. This study calculated intra-mat, intra-manufacturer, and inter-manufacturer reliability of plantar pressure parameters as well as the number of plantar pressure trials needed to reach a stable estimate of the mean for an individual. Twenty-two healthy adults completed ten walking trials across each of two Novel emed-x(®) and two Tekscan MatScan(®) plantar pressure measuring devices in a single visit. Intraclass correlation (ICC) was used to describe the agreement between values measured by different devices. All intra-platform reliability correlations were greater than 0.70. All inter-emed-x(®) reliability correlations were greater than 0.70. Inter-MatScan(®) reliability correlations were greater than 0.70 in 31 and 52 of 56 parameters when looking at a 10-trial average and a 5-trial average, respectively. Inter-manufacturer reliability including all four devices was greater than 0.70 for 52 and 56 of 56 parameters when looking at a 10-trial average and a 5-trial average, respectively. All parameters reached a value within 90% of an unbiased estimate of the mean within five trials. Overall, reliability results are encouraging for investigators and clinicians who may have plantar pressure data sets that include data collected on different devices.

  5. Simple estimates of the hidden beauty pentaquarks masses

    CERN Document Server

    Kopeliovich, Vladimir

    2015-01-01

    The masses of cryptoexotic pentaquarks with hidden beauty are estimated phenomenologically using the results by the LHCb collaboration which discovered recently the cryptoexotic pentaquarks with hidden charm. The expected masses of the hidden beauty pentaquarks are about $10.8\\, GeV$ and $10.7\\,GeV$ in the limit of some kind of heavy quark symmetry. The states with hidden strangeness considered in similar way have masses above $2\\, Gev$, by several hundreds of $MeV$ higher than states discussed previously in connection with the relatively light positive strangeness pentaquark $\\theta^+$.

  6. Critical scaling in hidden state inference for linear Langevin dynamics

    OpenAIRE

    Bravi, Barbara; Sollich, Peter

    2016-01-01

    We consider the problem of inferring the dynamics of unknown (i.e. hidden) nodes from a set of observed trajectories and we study analytically the average prediction error given by the Extended Plefka Expansion applied to it, as presented in [1]. We focus on a stochastic linear dynamics of continuous degrees of freedom interacting via random Gaussian couplings in the infinite network size limit. The expected error on the hidden time courses can be found as the equal-time hidden-to-hidden cova...

  7. Error statistics of hidden Markov model and hidden Boltzmann model results

    Directory of Open Access Journals (Sweden)

    Newberg Lee A

    2009-07-01

    Full Text Available Abstract Background Hidden Markov models and hidden Boltzmann models are employed in computational biology and a variety of other scientific fields for a variety of analyses of sequential data. Whether the associated algorithms are used to compute an actual probability or, more generally, an odds ratio or some other score, a frequent requirement is that the error statistics of a given score be known. What is the chance that random data would achieve that score or better? What is the chance that a real signal would achieve a given score threshold? Results Here we present a novel general approach to estimating these false positive and true positive rates that is significantly more efficient than are existing general approaches. We validate the technique via an implementation within the HMMER 3.0 package, which scans DNA or protein sequence databases for patterns of interest, using a profile-HMM. Conclusion The new approach is faster than general naïve sampling approaches, and more general than other current approaches. It provides an efficient mechanism by which to estimate error statistics for hidden Markov model and hidden Boltzmann model results.

  8. Error statistics of hidden Markov model and hidden Boltzmann model results

    Science.gov (United States)

    Newberg, Lee A

    2009-01-01

    Background Hidden Markov models and hidden Boltzmann models are employed in computational biology and a variety of other scientific fields for a variety of analyses of sequential data. Whether the associated algorithms are used to compute an actual probability or, more generally, an odds ratio or some other score, a frequent requirement is that the error statistics of a given score be known. What is the chance that random data would achieve that score or better? What is the chance that a real signal would achieve a given score threshold? Results Here we present a novel general approach to estimating these false positive and true positive rates that is significantly more efficient than are existing general approaches. We validate the technique via an implementation within the HMMER 3.0 package, which scans DNA or protein sequence databases for patterns of interest, using a profile-HMM. Conclusion The new approach is faster than general naïve sampling approaches, and more general than other current approaches. It provides an efficient mechanism by which to estimate error statistics for hidden Markov model and hidden Boltzmann model results. PMID:19589158

  9. ITS Platform North Denmark

    DEFF Research Database (Denmark)

    Lahrmann, Harry; Agerholm, Niels; Juhl, Jens

    2012-01-01

    This paper presents the project entitled “ITS Platform North Denmark” which is used as a test platform for Intelligent Transportation System (ITS) solutions. The platform consists of a newly developed GNSS/GPRS On Board Unit (OBU) to be installed in 500 cars, a backend server and a specially...... designed digital road map for ITS applications. The platform is freely accessible, which means that third party applications could be run on the platform. It is estimated that using this platform enables the ITS applications to be developed for 20% of the normal cost, hence third party are invited to test...... their applications in this platform. This paper presents the platform’s potentials and explains a series of test applications which are under development on it. Moreover, a number of new projects planned for the platform are demonstrated....

  10. Evolving the structure of hidden Markov Models

    DEFF Research Database (Denmark)

    won, K. J.; Prugel-Bennett, A.; Krogh, A.

    2006-01-01

    A genetic algorithm (GA) is proposed for finding the structure of hidden Markov Models (HMMs) used for biological sequence analysis. The GA is designed to preserve biologically meaningful building blocks. The search through the space of HMM structures is combined with optimization of the emission...... and transition probabilities using the classic Baum-Welch algorithm. The system is tested on the problem of finding the promoter and coding region of C. jejuni. The resulting HMM has a superior discrimination ability to a handcrafted model that has been published in the literature....

  11. OFDM System Channel Estimation with Hidden Pilot

    Institute of Scientific and Technical Information of China (English)

    YANG Feng; LIN Cheng-yu; ZHANG Wen-jun

    2007-01-01

    Channel estimation using pilot is common used in OFDM system. The pilot is usually time division multiplexed with the informative sequence. One of the main drawbacks is bandwidth losing. In this paper, a new method was proposed to perform channel estimation in OFDM system. The pilot is arithmetically added to the output of OFDM modulator. Receiver uses the hidden pilot to get an accurate estimation of the channel. Then pilot is removed after channel estimation. The Cramer-Rao lower bound for this method was deprived. The performance of the algorithm is then shown. Compared with traditional methods, the proposed algorithm increases the bandwidth efficiency dramatically.

  12. Pruning Boltzmann networks and hidden Markov models

    DEFF Research Database (Denmark)

    Pedersen, Morten With; Stork, D.

    1996-01-01

    We present sensitivity-based pruning algorithms for general Boltzmann networks. Central to our methods is the efficient calculation of a second-order approximation to the true weight saliencies in a cross-entropy error. Building upon previous work which shows a formal correspondence between linear...... Boltzmann chains and hidden Markov models (HMMs), we argue that our method can be applied to HMMs as well. We illustrate pruning on Boltzmann zippers, which are equivalent to two HMMs with cross-connection links. We verify that our second-order approximation preserves the rank ordering of weight saliencies...

  13. Hidden photon CDM search at Tokyo

    CERN Document Server

    Suzuki, Jun'ya; Horie, Tomoki; Minowa, Makoto

    2015-01-01

    We report on a search for hidden photon cold dark matter (HP CDM) using a novel technique with a dish antenna. We constructed two independent apparatus: one is aiming at the detection of the HP with a mass of $\\sim\\,\\rm{eV}$ which employs optical instruments, and the other is for a mass of $\\sim5\\times10^{-5}\\, \\rm{eV}$ utilizing a commercially available parabolic antenna facing on a plane reflector. From the result of the measurements, we found no evidence for the existence of HP CDM and set upper limits on the photon-HP mixing parameter $\\chi$.

  14. Maurice Halbwachs: Official and hidden memory

    Directory of Open Access Journals (Sweden)

    Carretero, Angel

    2008-05-01

    Full Text Available This article tries to show, in general terms, how Maurice Halbwachs has discovered presence and vitality in the collective memorieswhich have been excluded from the socially-institutionalized world. In order to decipher his opaque writing, one should try for a sociology of the depths, for a sociological look that, separating itself from the dominant positivism of the social sciences, manages to penetrate the hidden logic that permanently underlies social life. This article seeks to uncover the nature of a collective memory that respects the vicissitudes of time, as well as its difficult relations both with official memory and with the dominant historical record.

  15. Die Beharrlichkeit im Verborgenen Hidden Persistence

    Directory of Open Access Journals (Sweden)

    Paula-Irene Villa

    2003-07-01

    Full Text Available Karin Flaake geht in ihrer psychoanalytischen Interpretation innerfamilialer Konstellationen der Frage nach, wie das Zur-Frau-Werden von jungen Frauen erlebt wird. Dabei kommt den körperliche Wandlungsprozessen der Pubertät und den darin eingelagerten expliziten sowie verborgenen Deutungen des Weiblichen – vor allem des weiblichen Körpers – durch die Eltern eine prominente Rolle zu.Karin Flaake’s psychoanalytical intepretations of family constellations explore how young women experience their coming of age and entering womanhood. Her analysis focuses on the bodily changes which women undergo during puberty and the explicit as well as hidden meanings assigned to them by the parents.

  16. Scaling dimensions in hidden Kerr/CFT

    CERN Document Server

    Lowe, David A; Skanata, Antun

    2011-01-01

    It has been proposed that a hidden conformal field theory (CFT) governs the dynamics of low frequency scattering in a general Kerr black hole background. We further investigate this correspondence by mapping higher order corrections to the massless wave equations in a Kerr background to an expansion within the CFT in terms of higher dimension operators. This implies the presence of infinite towers of CFT primary operators with positive conformal dimensions compatible with unitarity. The exact Kerr background softly breaks the conformal symmetry and the scaling dimensions of these operators run with frequency. The scale-invariant fixed point is dual to a degenerate case of flat spacetime.

  17. Hidden Kerr/CFT at finite frequencies

    CERN Document Server

    Lowe, David A; Skanata, Antun

    2013-01-01

    Massless fields propagating in a generic Kerr black hole background enjoy a hidden SL(2,R)xSL(2,R) symmetry. We determine how the exact mode functions decompose into representations of this symmetry group. This extends earlier results on the low frequency limit of the massless scalar case to finite frequencies and general spin. As an application, we numerically determine the parameters of the representations that appear in quasinormal modes. These results represent a first step to formulating a more precise mapping to a holographic dual conformal field theory for generic black holes.

  18. A New Hidden Web Crawling Approach

    OpenAIRE

    L.Saoudi; A.Boukerram; S.Mhamedi

    2015-01-01

    Traditional search engines deal with the Surface Web which is a set of Web pages directly accessible through hyperlinks and ignores a large part of the Web called hidden Web which is a great amount of valuable information of online database which is “hidden” behind the query forms. To access to those information the crawler have to fill the forms with a valid data, for this reason we propose a new approach which use SQLI technique in order to find the most promising keywords of a specific dom...

  19. Hidden Scale Invariance in Condensed Matter

    DEFF Research Database (Denmark)

    Dyre, J. C.

    2014-01-01

    . This means that the phase diagram becomes effectively one-dimensional with regard to several physical properties. Liquids and solids with isomorphs include most or all van der Waals bonded systems and metals, as well as weakly ionic or dipolar systems. On the other hand, systems with directional bonding...... (hydrogen bonds or covalent bonds) or strong Coulomb forces generally do not exhibit hidden scale invariance. The article reviews the theory behind this picture of condensed matter and the evidence for it coming from computer simulations and experiments...

  20. Genetic Algorithms Principles Towards Hidden Markov Model

    Directory of Open Access Journals (Sweden)

    Nabil M. Hewahi

    2011-10-01

    Full Text Available In this paper we propose a general approach based on Genetic Algorithms (GAs to evolve Hidden Markov Models (HMM. The problem appears when experts assign probability values for HMM, they use only some limited inputs. The assigned probability values might not be accurate to serve in other cases related to the same domain. We introduce an approach based on GAs to find
    out the suitable probability values for the HMM to be mostly correct in more cases than what have been used to assign the probability values.

  1. Fifty Years After, Hidden Children Speak

    Directory of Open Access Journals (Sweden)

    Léa Marcou

    2008-06-01

    Full Text Available “For fifty years, I have not spoken of my childhood years in France during the second world war. A hidden child, I lived under a false name amongst unknown people, being careful – as I had been taught – not to reveal, by a gesture or by a word, that I was Jewish. I knew I was in danger, still not understanding why and I was constantly afraid. I didn't know whether I would see again one day my parents from whom I had been suddenly taken away. Nonetheless what were my pains compared to those of...

  2. Detecting Structural Breaks using Hidden Markov Models

    DEFF Research Database (Denmark)

    Ntantamis, Christos

    Testing for structural breaks and identifying their location is essential for econometric modeling. In this paper, a Hidden Markov Model (HMM) approach is used in order to perform these tasks. Breaks are defined as the data points where the underlying Markov Chain switches from one state to another....... The locations of the breaks are subsequently obtained by assigning states to data points according to the Maximum Posterior Mode (MPM) algorithm. The Integrated Classification Likelihood-Bayesian Information Criterion (ICL-BIC) allows for the determination of the number of regimes by taking into account...... in the monetary policy of United States, the dierent functional form being variants of the Taylor (1993) rule....

  3. Uncovering the Hidden Costs of Offshoring

    DEFF Research Database (Denmark)

    Larsen, Marcus M.; Manning, Stephan; Pedersen, Torben

    2013-01-01

    This study investigates estimation errors due to hidden costs—the costs of implementation that are neglected in strategic decision-making processes—in the context of services offshoring. Based on data from the Offshoring Research Network, we find that decision makers are more likely to make cost......-estimation errors given increasing configuration and task complexity in captive offshoring and offshore outsourcing, respectively. Moreover, we show that experience and a strong orientation toward organizational design in the offshoring strategy reduce the cost-estimation errors that follow from complexity. Our...

  4. Mobile platform security

    CERN Document Server

    Asokan, N; Dmitrienko, Alexandra

    2013-01-01

    Recently, mobile security has garnered considerable interest in both the research community and industry due to the popularity of smartphones. The current smartphone platforms are open systems that allow application development, also for malicious parties. To protect the mobile device, its user, and other mobile ecosystem stakeholders such as network operators, application execution is controlled by a platform security architecture. This book explores how such mobile platform security architectures work. We present a generic model for mobile platform security architectures: the model illustrat

  5. Women's hidden transcripts about abortion in Brazil.

    Science.gov (United States)

    Nations, M K; Misago, C; Fonseca, W; Correia, L L; Campbell, O M

    1997-06-01

    Two folk medical conditions, "delayed" (atrasada) and "suspended" (suspendida) menstruation, are described as perceived by poor Brazilian women in Northeast Brazil. Culturally prescribed methods to "regulate" these conditions and provoke menstrual bleeding are also described, including ingesting herbal remedies, patent drugs, and modern pharmaceuticals. The ingestion of such self-administered remedies is facilitated by the cognitive ambiguity, euphemisms, folklore, etc., which surround conception and gestation. The authors argue that the ethnomedical conditions of "delayed" and "suspended" menstruation and subsequent menstrual regulation are part of the "hidden reproductive transcript" of poor and powerless Brazilian women. Through popular culture, they voice their collective dissent to the official, public opinion about the illegality and immorality of induced abortion and the chronic lack of family planning services in Northeast Brazil. While many health professionals consider women's explanations of menstrual regulation as a "cover-up" for self-induced abortions, such popular justifications may represent either an unconscious or artful manipulation of hegemonic, anti-abortion ideology expressed in prudent, unobtrusive and veiled ways. The development of safer abortion alternatives should consider women's hidden reproductive transcripts.

  6. Atlas of solar hidden photon emission

    Energy Technology Data Exchange (ETDEWEB)

    Redondo, Javier [Departamento de Física Teórica, Universidad de Zaragoza,Pedro Cerbuna 12, E-50009, Zaragoza (Spain); Max-Planck-Institut für Physik, Werner-Heisenberg-Institut,Föhringer Ring 6, 80805 München (Germany)

    2015-07-20

    Hidden photons, gauge bosons of a U(1) symmetry of a hidden sector, can constitute the dark matter of the universe and a smoking gun for large volume compactifications of string theory. In the sub-eV mass range, a possible discovery experiment consists on searching the copious flux of these particles emitted from the Sun in a helioscope setup à la Sikivie. In this paper, we compute in great detail the flux of HPs from the Sun, a necessary ingredient for interpreting such experiments. We provide a detailed exposition of transverse photon-HP oscillations in inhomogenous media, with special focus on resonance oscillations, which play a leading role in many cases. The region of the Sun emitting HPs resonantly is a thin spherical shell for which we justify an averaged-emission formula and which implies a distinctive morphology of the angular distribution of HPs on Earth in many cases. Low mass HPs with energies in the visible and IR have resonances very close to the photosphere where the solar plasma is not fully ionised and requires building a detailed model of solar refraction and absorption. We present results for a broad range of HP masses (from 0–1 keV) and energies (from the IR to the X-ray range), the most complete atlas of solar HP emission to date.

  7. Epitope discovery with phylogenetic hidden Markov models.

    LENUS (Irish Health Repository)

    Lacerda, Miguel

    2010-05-01

    Existing methods for the prediction of immunologically active T-cell epitopes are based on the amino acid sequence or structure of pathogen proteins. Additional information regarding the locations of epitopes may be acquired by considering the evolution of viruses in hosts with different immune backgrounds. In particular, immune-dependent evolutionary patterns at sites within or near T-cell epitopes can be used to enhance epitope identification. We have developed a mutation-selection model of T-cell epitope evolution that allows the human leukocyte antigen (HLA) genotype of the host to influence the evolutionary process. This is one of the first examples of the incorporation of environmental parameters into a phylogenetic model and has many other potential applications where the selection pressures exerted on an organism can be related directly to environmental factors. We combine this novel evolutionary model with a hidden Markov model to identify contiguous amino acid positions that appear to evolve under immune pressure in the presence of specific host immune alleles and that therefore represent potential epitopes. This phylogenetic hidden Markov model provides a rigorous probabilistic framework that can be combined with sequence or structural information to improve epitope prediction. As a demonstration, we apply the model to a data set of HIV-1 protein-coding sequences and host HLA genotypes.

  8. Atlas of solar hidden photon emission

    CERN Document Server

    Redondo, Javier

    2015-01-01

    Hidden photons, gauge bosons of a U(1) symmetry of a hidden sector, can constitute the dark matter of the universe and a smoking gun for large volume compactifications of string theory. In the sub-eV mass range, a possible discovery experiment consists on searching the copious flux of these particles emitted from the Sun in a helioscope setup \\`a la Sikivie. In this paper, we compute the flux of transversely polarised HPs from the Sun, a necessary ingredient for interpreting such experiments. We provide a detailed exposition of photon-HP oscillations in inhomogenous media, with special focus on resonance oscillations, which play a leading role in many cases. The region of the Sun emitting HPs resonantly is a thin spherical shell for which we justify an averaged-emission formula and which implies a distinctive morphology of the angular distribution of HPs on Earth in many cases. Low mass HPs with energies in the visible and IR have resonances very close to the photosphere where the solar plasma is not fully io...

  9. Quantum Hidden Subgroup Problems A Mathematical Perspective

    CERN Document Server

    Lomonaco, S J; Lomonaco, Samuel J.; Kauffman, Louis H.

    2002-01-01

    The ultimate objective of this paper is to create a stepping stone to the development of new quantum algorithms. The strategy chosen is to begin by focusing on the class of abelian quantum hidden subgroup algorithms, i.e., the class of abelian algorithms of the Shor/Simon genre. Our strategy is to make this class of algorithms as mathematically transparent as possible. By the phrase "mathematically transparent" we mean to expose, to bring to the surface, and to make explicit the concealed mathematical structures that are inherently and fundamentally a part of such algorithms. In so doing, we create symbolic abelian quantum hidden subgroup algorithms that are analogous to the those symbolic algorithms found within such software packages as Axiom, Cayley, Maple, Mathematica, and Magma. As a spin-off of this effort, we create three different generalizations of Shor's quantum factoring algorithm to free abelian groups of finite rank. We refer to these algorithms as wandering (or vintage Z_Q) Shor algorithms. They...

  10. ESO's Hidden Treasures Brought to Light

    Science.gov (United States)

    2011-01-01

    ESO's Hidden Treasures 2010 astrophotography competition attracted nearly 100 entries, and ESO is delighted to announce the winners. Hidden Treasures gave amateur astronomers the opportunity to search ESO's vast archives of astronomical data for a well-hidden cosmic gem. Astronomy enthusiast Igor Chekalin from Russia won the first prize in this difficult but rewarding challenge - the trip of a lifetime to ESO's Very Large Telescope at Paranal, Chile. The pictures of the Universe that can be seen in ESO's releases are impressive. However, many hours of skilful work are required to assemble the raw greyscale data captured by the telescopes into these colourful images, correcting them for distortions and unwanted signatures of the instrument, and enhancing them so as to bring out the details contained in the astronomical data. ESO has a team of professional image processors, but for the ESO's Hidden Treasures 2010 competition, the experts decided to give astronomy and photography enthusiasts the opportunity to show the world what they could do with the mammoth amount of data contained in ESO's archives. The enthusiasts who responded to the call submitted nearly 100 entries in total - far exceeding initial expectations, given the difficult nature of the challenge. "We were completely taken aback both by the quantity and the quality of the images that were submitted. This was not a challenge for the faint-hearted, requiring both an advanced knowledge of data processing and an artistic eye. We are thrilled to have discovered so many talented people," said Lars Lindberg Christensen, Head of ESO's education and Public Outreach Department. Digging through many terabytes of professional astronomical data, the entrants had to identify a series of greyscale images of a celestial object that would reveal the hidden beauty of our Universe. The chance of a great reward for the lucky winner was enough to spur on the competitors; the first prize being a trip to ESO's Very Large

  11. Hidden Markov Model for Stock Selection

    Directory of Open Access Journals (Sweden)

    Nguyet Nguyen

    2015-10-01

    Full Text Available The hidden Markov model (HMM is typically used to predict the hidden regimes of observation data. Therefore, this model finds applications in many different areas, such as speech recognition systems, computational molecular biology and financial market predictions. In this paper, we use HMM for stock selection. We first use HMM to make monthly regime predictions for the four macroeconomic variables: inflation (consumer price index (CPI, industrial production index (INDPRO, stock market index (S&P 500 and market volatility (VIX. At the end of each month, we calibrate HMM’s parameters for each of these economic variables and predict its regimes for the next month. We then look back into historical data to find the time periods for which the four variables had similar regimes with the forecasted regimes. Within those similar periods, we analyze all of the S&P 500 stocks to identify which stock characteristics have been well rewarded during the time periods and assign scores and corresponding weights for each of the stock characteristics. A composite score of each stock is calculated based on the scores and weights of its features. Based on this algorithm, we choose the 50 top ranking stocks to buy. We compare the performances of the portfolio with the benchmark index, S&P 500. With an initial investment of $100 in December 1999, over 15 years, in December 2014, our portfolio had an average gain per annum of 14.9% versus 2.3% for the S&P 500.

  12. Hidden charm molecules in finite volume

    CERN Document Server

    Albaladejo, Miguel; Nieves, Juan; Oset, Eulogio

    2013-01-01

    In the present paper we address the interaction of pairs of charmed mesons with hidden charm in a finite box. We use the interaction from a recent model based on heavy quark spin symmetry that predicts molecules of hidden charm in the infinite volume. The energy levels in the box are generated within this model, and from them some synthetic data are generated. These data are then employed to study the inverse problem of getting the energies of the bound states and phase shifts for $D \\bar D$ or $D^* {\\bar D}^*$. Different strategies are investigated using the lowest two levels for different values of the box size, carrying a study of the errors produced. Starting from the upper level, fits to the synthetic data are carried out to determine the scattering length and effective range plus the binding energy of the ground state. A similar strategy using the effective range formula is considered with a simultaneous fit to the two levels, one above and the other one below threshold. This method turns out to be more...

  13. Laser experiments explore the hidden sector

    Energy Technology Data Exchange (ETDEWEB)

    Ahlers, M. [Oxford Univ. (United Kingdom). Rudolf Peierls Centre for Theoretical Physics; Gies, H. [Heidelberg Univ. (Germany). Inst. fuer Theoretische Physik; Jaeckel, J. [Heidelberg Univ. (Germany). Inst. fuer Theoretische Physik]|[Durham Univ. (United Kingdom). Inst. for Particle Physics Phenomenology; Redondo, J.; Ringwald, A. [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)

    2007-11-15

    Recently, the laser experiments BMV and GammeV, searching for light shining through walls, have published data and calculated new limits on the allowed masses and couplings for axion-like particles. In this note we point out that these experiments can serve to constrain a much wider variety of hidden-sector particles such as, e.g., minicharged particles and hidden-sector photons. The new experiments improve the existing bounds from the older BFRT experiment by a factor of two. Moreover, we use the new PVLAS constraints on a possible rotation and ellipticity of light after it has passed through a strong magnetic field to constrain pure minicharged particle models. For masses

  14. Bayesian structural inference for hidden processes.

    Science.gov (United States)

    Strelioff, Christopher C; Crutchfield, James P

    2014-04-01

    We introduce a Bayesian approach to discovering patterns in structurally complex processes. The proposed method of Bayesian structural inference (BSI) relies on a set of candidate unifilar hidden Markov model (uHMM) topologies for inference of process structure from a data series. We employ a recently developed exact enumeration of topological ε-machines. (A sequel then removes the topological restriction.) This subset of the uHMM topologies has the added benefit that inferred models are guaranteed to be ε-machines, irrespective of estimated transition probabilities. Properties of ε-machines and uHMMs allow for the derivation of analytic expressions for estimating transition probabilities, inferring start states, and comparing the posterior probability of candidate model topologies, despite process internal structure being only indirectly present in data. We demonstrate BSI's effectiveness in estimating a process's randomness, as reflected by the Shannon entropy rate, and its structure, as quantified by the statistical complexity. We also compare using the posterior distribution over candidate models and the single, maximum a posteriori model for point estimation and show that the former more accurately reflects uncertainty in estimated values. We apply BSI to in-class examples of finite- and infinite-order Markov processes, as well to an out-of-class, infinite-state hidden process.

  15. TrustMAS: Trusted Communication Platform for Multi-Agent Systems

    CERN Document Server

    Szczypiorski, Krzysztof; Mazurczyk, Wojciech; Cabaj, Krzysztof; Radziszewski, Pawel

    2008-01-01

    The paper presents TrustMAS - Trusted Communication Platform for Multi-Agent Systems, which provides trust and anonymity for mobile agents. The platform includes anonymous technique based on random-walk algorithm for providing general purpose anonymous communication for agents. All agents, which take part in the proposed platform, benefit from trust and anonymity that is provided for their interactions. Moreover, in TrustMAS there are StegAgents (SA) that are able to perform various steganographic communication. To achieve that goal, SAs may use methods in different layers of TCP/IP model or specialized middleware enabling steganography that allows hidden communication through all layers of mentioned model. In TrustMAS steganographic channels are used to exchange routing tables between StegAgents. Thus all StegAgents in TrustMAS with their ability to exchange information by using hidden channels form distributed steganographic router (Stegrouter).

  16. Continuous Platform Development

    DEFF Research Database (Denmark)

    Nielsen, Ole Fiil

    low risks and investments but also with relatively fuzzy results. When looking for new platform projects, it is important to make sure that the company and market is ready for the introduction of platforms, and to make sure that people from marketing and sales, product development, and downstream......, but continuous product family evolution challenges this strategy. The concept of continuous platform development is based on the fact that platform development should not be a one-time experience but rather an ongoing process of developing new platforms and updating existing ones, so that product family...

  17. Quantum algorithm for identifying hidden polynomial function graphs

    NARCIS (Netherlands)

    Decker, T.; Draisma, J.; Wocjan, P.

    2009-01-01

    We consider a natural generalization of an abelian Hidden Subgroup Problem where the subgroups and their cosets correspond to graphs of linear functions over a finite field F with d elements. The hidden functions of the generalized problem are not restricted to be linear but can also be m-variate po

  18. Hidden attractor in the Rabinovich system, Chua circuits and PLL

    Science.gov (United States)

    Kuznetsov, N. V.; Leonov, G. A.; Mokaev, T. N.; Seledzhi, S. M.

    2016-06-01

    In this report the existence of hidden attractors in Rabinovich system, phase-locked loop and coupled Chua circuits is considered. It is shown that the existence of hidden attractors may complicate the analysis of the systems and significantly affect the synchronization.

  19. Hidden Curriculum as One of Current Issue of Curriculum

    Science.gov (United States)

    Alsubaie, Merfat Ayesh

    2015-01-01

    There are several issues in the education system, especially in the curriculum field that affect education. Hidden curriculum is one of current controversial curriculum issues. Many hidden curricular issues are the result of assumptions and expectations that are not formally communicated, established, or conveyed within the learning environment.…

  20. Searching for hidden sector in multiparticle production at LHC

    Directory of Open Access Journals (Sweden)

    Miguel-Angel Sanchis-Lozano

    2016-03-01

    Full Text Available We study the impact of a hidden sector beyond the Standard Model, e.g. a Hidden Valley model, on factorial moments and cumulants of multiplicity distributions in multiparticle production with a special emphasis on the prospects for LHC results.

  1. Secret Codes: The Hidden Curriculum of Semantic Web Technologies

    Science.gov (United States)

    Edwards, Richard; Carmichael, Patrick

    2012-01-01

    There is a long tradition in education of examination of the hidden curriculum, those elements which are implicit or tacit to the formal goals of education. This article draws upon that tradition to open up for investigation the hidden curriculum and assumptions about students and knowledge that are embedded in the coding undertaken to facilitate…

  2. Secret Codes: The Hidden Curriculum of Semantic Web Technologies

    Science.gov (United States)

    Edwards, Richard; Carmichael, Patrick

    2012-01-01

    There is a long tradition in education of examination of the hidden curriculum, those elements which are implicit or tacit to the formal goals of education. This article draws upon that tradition to open up for investigation the hidden curriculum and assumptions about students and knowledge that are embedded in the coding undertaken to facilitate…

  3. Seuss's Butter Battle Book: Is There Hidden Harm?

    Science.gov (United States)

    Van Cleaf, David W.; Martin, Rita J.

    1986-01-01

    Examines whether elementary school children relate to the "harmful hidden message" about nuclear war in Dr. Seuss's THE BUTTER BATTLE BOOK. After ascertaining the children's cognitive level, they participated in activities to find hidden meanings in stories, including Seuss's book. Students failed to identify the nuclear war message in Seuss's…

  4. An introduction to hidden Markov models for biological sequences

    DEFF Research Database (Denmark)

    Krogh, Anders Stærmose

    1998-01-01

    A non-matematical tutorial on hidden Markov models (HMMs) plus a description of one of the applications of HMMs: gene finding.......A non-matematical tutorial on hidden Markov models (HMMs) plus a description of one of the applications of HMMs: gene finding....

  5. Detecting Hidden Hierarchy of Non Hierarchical Terrorist Networks

    DEFF Research Database (Denmark)

    Memon, Nasrullah

    to analyze terrorist networks and prioritize their targets. Applying recently introduced mathematical methods for constructing the hidden hierarchy of "nonhierarchical" terrorist networks; we present case studies of the terrorist attacks occurred / planned in the past, in order to identify hidden hierarchy...

  6. Cross-Platform Technologies

    Directory of Open Access Journals (Sweden)

    Maria Cristina ENACHE

    2017-04-01

    Full Text Available Cross-platform - a concept becoming increasingly used in recent years especially in the development of mobile apps, but this consistently over time and in the development of conventional desktop applications. The notion of cross-platform software (multi-platform or platform-independent refers to a software application that can run on more than one operating system or computing architecture. Thus, a cross-platform application can operate independent of software or hardware platform on which it is execute. As a generic definition presents a wide range of meanings for purposes of this paper we individualize this definition as follows: we will reduce the horizon of meaning and we use functionally following definition: a cross-platform application is a software application that can run on more than one operating system (desktop or mobile identical or in a similar way.

  7. A Radio for Hidden-Photon Dark Matter Detection

    CERN Document Server

    Chaudhuri, Saptarshi; Irwin, Kent; Mardon, Jeremy; Rajendran, Surjeet; Zhao, Yue

    2014-01-01

    We propose a resonant electromagnetic detector to search for hidden-photon dark matter over an extensive range of masses. Hidden-photon dark matter can be described as a weakly coupled "hidden electric field," oscillating at a frequency fixed by the mass, and able to penetrate any shielding. At low frequencies (compared to the inverse size of the shielding), we find that observable effect of the hidden photon inside any shielding is a real, oscillating magnetic field. We outline experimental setups designed to search for hidden-photon dark matter, using a tunable, resonant LC circuit designed to couple to this magnetic field. Our "straw man" setups take into consideration resonator design, readout architecture and noise estimates. At high frequencies,there is an upper limit to the useful size of a single resonator set by $1/\

  8. Secluded Dark Matter Coupled to a Hidden CFT

    CERN Document Server

    von Harling, Benedict

    2012-01-01

    Models of secluded dark matter offer a variant on the standard WIMP picture and can modify our expectations for hidden sector phenomenology and detection. In this work we extend a minimal model of secluded dark matter, comprised of a U(1)'-charged dark matter candidate, to include a confining hidden-sector CFT. This provides a technically natural explanation for the hierarchically small mediator-scale, with hidden-sector confinement generating m_{gamma'}>0. Furthermore, the thermal history of the universe can differ markedly from the WIMP picture due to (i) new annihilation channels, (ii) a (potentially) large number of hidden-sector degrees of freedom, and (iii) a hidden-sector phase transition at temperatures T << M_{dm} after freeze out. The mediator allows both the dark matter and the Standard Model to communicate with the CFT, thus modifying the low-energy phenomenology and cosmic-ray signals from the secluded sector.

  9. Abelian Hidden Sectors at a GeV

    Energy Technology Data Exchange (ETDEWEB)

    Morrissey, David E.; Poland, David; /Harvard U.; Zurek, Kathryn; /Fermilab /Michigan U.

    2009-04-16

    We discuss mechanisms for naturally generating GeV-scale hidden sectors in the context of weak-scale supersymmetry. Such low mass scales can arise when hidden sectors are more weakly coupled to supersymmetry breaking than the visible sector, as happens when supersymmetry breaking is communicated to the visible sector by gauge interactions under which the hidden sector is uncharged, or if the hidden sector is sequestered from gravity-mediated supersymmetry breaking. We study these mechanisms in detail in the context of gauge and gaugino mediation, and present specific models of Abelian GeV-scale hidden sectors. In particular, we discuss kinetic mixing of a U(1){sub x} gauge force with hypercharge, singlets or bi-fundamentals which couple to both sectors, and additional loop effects. Finally, we investigate the possible relevance of such sectors for dark matter phenomenology, as well as for low- and high-energy collider searches.

  10. HIDDEN WEB EXTRACTOR DYNAMIC WAY TO UNCOVER THE DEEP WEB

    Directory of Open Access Journals (Sweden)

    DR. ANURADHA

    2012-06-01

    Full Text Available In this era of digital tsunami of information on the web, everyone is completely dependent on the WWW for information retrieval. This has posed a challenging problem in extracting relevant data. Traditional web crawlers focus only on the surface web while the deep web keeps expanding behind the scene. The web databases are hidden behind the query interfaces. In this paper, we propose a Hidden Web Extractor (HWE that can automatically discover and download data from the Hidden Web databases. Since the only “entry point” to a Hidden Web site is a query interface, the main challenge that a Hidden WebExtractor has to face is how to automatically generate meaningful queries for the unlimited number of website pages.

  11. Gauge Coupling Unification with Hidden Photon, and Minicharged Dark Matter

    CERN Document Server

    Daido, Ryuji; Yokozaki, Norimi

    2016-01-01

    We show that gauge coupling unification is realized with a greater accuracy in the presence of a massless hidden photon which has a large kinetic mixing with hypercharge. We solve the renormalization group equations at two-loop level and find that the GUT unification scale is around $10^{16.5}$ GeV which sufficiently suppresses the proton decay rate, and that the unification depends only on the kinetic mixing, but not on the hidden gauge coupling nor the presence of vector-like matter fields charged under U(1)$_H$ and/or SU(5). Matter fields charged under the unbroken hidden U(1)$_H$ are stable and they contribute to dark matter. Interestingly, they become minicharged dark matter which carries a small but non-zero electric charge, if the hidden gauge coupling is tiny. The minicharged dark matter is a natural outcome of the gauge coupling unification with a hidden photon.

  12. A Hidden-Removal Model of Dam Perspective Drawing

    Institute of Scientific and Technical Information of China (English)

    WANG Zi-ru; ZHOU Hui-cheng; LI Ming-qiu

    2011-01-01

    Aming at water conservancy project visualization, a hidden-removal method of dam perspective drawings is realized by building a hidden-removal mathematical model for overlapping points location to set up the hidden relationship among point and plane, plane and plane in space. On this basis, as an example of panel rockfill dam, a dam hidden-removal perspective drawing is generated in different directions and different visual angles through adapting VC++ and OpenGL visualizing technology. The results show that the data construction of the model is simple which can overcome the disadvantages of considerable and complicated calculation. This method also provides the new means to draw hidden-removal perspective drawings for those landforms and ground objects.

  13. Next generation sequencing reveals the hidden diversity of zooplankton assemblages.

    Directory of Open Access Journals (Sweden)

    Penelope K Lindeque

    Full Text Available BACKGROUND: Zooplankton play an important role in our oceans, in biogeochemical cycling and providing a food source for commercially important fish larvae. However, difficulties in correctly identifying zooplankton hinder our understanding of their roles in marine ecosystem functioning, and can prevent detection of long term changes in their community structure. The advent of massively parallel next generation sequencing technology allows DNA sequence data to be recovered directly from whole community samples. Here we assess the ability of such sequencing to quantify richness and diversity of a mixed zooplankton assemblage from a productive time series site in the Western English Channel. METHODOLOGY/PRINCIPLE FINDINGS: Plankton net hauls (200 µm were taken at the Western Channel Observatory station L4 in September 2010 and January 2011. These samples were analysed by microscopy and metagenetic analysis of the 18S nuclear small subunit ribosomal RNA gene using the 454 pyrosequencing platform. Following quality control a total of 419,041 sequences were obtained for all samples. The sequences clustered into 205 operational taxonomic units using a 97% similarity cut-off. Allocation of taxonomy by comparison with the National Centre for Biotechnology Information database identified 135 OTUs to species level, 11 to genus level and 1 to order, <2.5% of sequences were classified as unknowns. By comparison a skilled microscopic analyst was able to routinely enumerate only 58 taxonomic groups. CONCLUSIONS: Metagenetics reveals a previously hidden taxonomic richness, especially for Copepoda and hard-to-identify meroplankton such as Bivalvia, Gastropoda and Polychaeta. It also reveals rare species and parasites. We conclude that Next Generation Sequencing of 18S amplicons is a powerful tool for elucidating the true diversity and species richness of zooplankton communities. While this approach allows for broad diversity assessments of plankton it may

  14. Identifying hidden sexual bridging communities in Chicago.

    Science.gov (United States)

    Youm, Yoosik; Mackesy-Amiti, Mary Ellen; Williams, Chyvette T; Ouellet, Lawrence J

    2009-07-01

    Bridge populations can play a central role in the spread of human immunodeficiency virus (HIV) by providing transmission links between higher and lower prevalence populations. While social network methods are well suited to the study of bridge populations, analyses tend to focus on dyads (i.e., risk between drug and/or sex partners) and ignore bridges between distinct subpopulations. This study takes initial steps toward moving the analysis of sexual network linkages beyond individual and risk group levels to a community level in which Chicago's 77 community areas are examined as subpopulations for the purpose of identifying potential bridging communities. Of particular interest are "hidden" bridging communities; that is, areas with above-average levels of sexual ties with other areas but whose below-average AIDS prevalence may hide their potential importance for HIV prevention. Data for this analysis came from the first wave of recruiting at the Chicago Sexual Acquisition and Transmission of HIV Cooperative Agreement Program site. Between August 2005 through October 2006, respondent-driven sampling was used to recruit users of heroin, cocaine, or methamphetamine, men who have sex with men regardless of drug use, the sex partners of these two groups, and sex partners of the sex partners. In this cross-sectional study of the sexual transmission of HIV, participants completed a network-focused computer-assisted self-administered interview, which included questions about the geographic locations of sexual contacts with up to six recent partners. Bridging scores for each area were determined using a matrix representing Chicago's 77 community areas and were assessed using two measures: non-redundant ties and flow betweenness. Bridging measures and acquired immunodeficiency syndrome (AIDS) case prevalence rates were plotted for each community area on charts representing four conditions: below-average bridging and AIDS prevalence, below-average bridging and above

  15. Magneto-Radar Hidden Metal Detector

    Energy Technology Data Exchange (ETDEWEB)

    McEwan, Thomas E. (Las Vegas, NV)

    2005-07-05

    A varying magnetic field excites slight vibrations in an object and a radar sensor detects the vibrations at a harmonic of the excitation frequency. The synergy of the magnetic excitation and radar detection provides increased detection range compared to conventional magnetic metal detectors. The radar rejects background clutter by responding only to reflecting objects that are vibrating at a harmonic excitation field, thereby significantly improving detection reliability. As an exemplary arrangement, an ultra-wideband micropower impulse radar (MIR) is capable of being employed to provide superior materials penetration while providing range information. The magneto-radar may be applied to pre-screening magnetic resonance imaging (MRI) patients, landmine detection and finding hidden treasures.

  16. Effect of Noise on hidden data

    Directory of Open Access Journals (Sweden)

    Garima Tomar

    2012-02-01

    Full Text Available This paper simulates an effective data hiding technique i.e. steganography based on LSB insertion and RSA encryption in order to provide seven million times better security than the previous work. The Main idea of proposed scheme is to encrypt secret data by RSA 1024 algorithm, convert it in to binary sequence bit and then embedded into each cover pixels by modifying the least significant bits (LSBs of cover pixels. The result image is also known as steganography image. The PSNR value of this steganography image is 54.34 db. In this paper Baboon image is used for experimental purpous.This steganography image is transmitted through AWGN channel, and performance is simulated. The image and hidden data are reconstructed with the SNR level ≥9 dB.

  17. Sending Hidden Data via Google Suggest

    CERN Document Server

    Bialczak, Piotr; Szczypiorski, Krzysztof

    2011-01-01

    Google Suggest is a service incorporated within Google Web Search which was created to help user find the right search phrase by proposing the autocompleting popular phrases while typing. The paper presents a new network steganography method called StegSuggest which utilizes suggestions generated by Google Suggest as a hidden data carrier. The detailed description of the method's idea is backed up with the analysis of the network traffic generated by the Google Suggest to prove its feasibility. The traffic analysis was also performed to discover the occurrence of two TCP options: Window Scale and Timestamp which StegSuggest uses to operate. Estimation of method steganographic bandwidth proves that it is possible to insert 100 bits of steganogram into every suggestions list sent by Google Suggest service.

  18. Grand unified hidden-sector dark matter

    Science.gov (United States)

    Lonsdale, Stephen J.; Volkas, Raymond R.

    2014-10-01

    We explore G×G unified theories with the visible and the hidden or dark sectors paired under a Z2 symmetry. Developing a system of "asymmetric symmetry breaking" we motivate such models on the basis of their ability to generate dark baryons that are confined with a mass scale just above that of the proton, as motivated by asymmetric dark matter. This difference is achieved from the distinct but related confinement scales that develop in unified theories that have the two factors of G spontaneously breaking in an asymmetric manner. We show how Higgs potentials that admit different gauge group breaking chains in each sector can be constructed, and demonstrate the capacity for generating different fermion mass scales. Lastly we discuss supersymmetric extensions of such schemes.

  19. Hidden caries’ challenge diagnosis: case report

    Directory of Open Access Journals (Sweden)

    Fernanda Mara de Paiva Bertoli

    2013-06-01

    Full Text Available Introduction: Hidden caries is a term used to describe occlusal dentine caries that is missed on a visual examination, but is large and demineralised enough to be detected by another exam for example, radiographs. Case report: This article reports a case of large dentine caries, which presented as to be a small pit-and-fissure carious lesion on the occlusal surface of the right mandibular permanent first molar in a 10-year-old girl. The treatment included root canal treatment and the sealing of the cavity with composite resin. Conclusion: Careful visual examination, with cleaning and drying of teeth, associated to bitewing radiographs may improve occlusal caries detection. Dentists should examine bitewing radiographs carefully for proximal caries and occlusal demineralization. Radiographs are an effective method of caries diagnosis that can avoid large destruction and allows less invasive treatment.

  20. Hidden expectations within the Danish VET system

    DEFF Research Database (Denmark)

    Hjort-Madsen, Peder

    Researching the pressing retention and dropout problems of the Danish VET system (app. 20 pct. of a year group never achieve an upper secondary education) this paper takes its point of departure in the hypothesis that low performing students are kept in a marginal position (at the risk of dropping...... out) within the VET system, because of hidden expectations related to e.g. individualized responsibility, a certain student behavior (sitting still, participating actively), etc. By approaching the VET system as a cultural context (cultural praxis) the subtle reproductive mechanisms of the VET system...... are shown. With empirical examples from different introductory VET courses, it is shown how the school, the teachers and the students themselves are reproducing poor school performance and student background – being it gendered, ethnical or social – and hereby proving to the students, that school...

  1. Hidden expectations within the Danish VET system

    DEFF Research Database (Denmark)

    Hjort-Madsen, Peder

    2011-01-01

    Researching the pressing retention and dropout problems of the Danish VET system (app. 20 pct. of a year group never achieve an upper secondary education) this paper takes its point of departure in the hypothesis that low performing students are kept in a marginal position (at the risk of dropping...... out) within the VET system, because of hidden expectations related to e.g. individualized responsibility, a certain student behavior (sitting still, participating actively), etc. By approaching the VET system as a cultural context (cultural praxis) the subtle reproductive mechanisms of the VET system...... are shown. With empirical examples from different introductory VET courses, it is shown how the school, the teachers and the students themselves are reproducing poor school performance and student background – being it gendered, ethnical or social – and hereby proving to the students, that school...

  2. Nuclear scissors modes and hidden angular momenta

    CERN Document Server

    Balbutsev, E B; Schuck, P

    2016-01-01

    The coupled dynamics of low lying modes and various giant resonances are studied with the help of the Wigner Function Moments method generalized to take into account spin degrees of freedom and pair correlations simultaneously. The method is based on Time Dependent Hartree-Fock-Bogoliubov equations. The model of the harmonic oscillator including spin-orbit potential plus quadrupole-quadrupole and spin-spin interactions is considered. New low lying spin dependent modes are analyzed. Special attention is paid to the scissors modes. A new source of nuclear magnetism, connected with counter-rotation of spins up and down around the symmetry axis (hidden angular momenta), is discovered. Its inclusion into the theory allows one to improve substantially the agreement with experimental data in the description of energies and transition probabilities of scissors modes.

  3. Hidden expectations within the Danish VET system

    DEFF Research Database (Denmark)

    Hjort-Madsen, Peder

    2011-01-01

    out) within the VET system, because of hidden expectations related to e.g. individualized responsibility, a certain student behavior (sitting still, participating actively), etc. By approaching the VET system as a cultural context (cultural praxis) the subtle reproductive mechanisms of the VET system...... are shown. With empirical examples from different introductory VET courses, it is shown how the school, the teachers and the students themselves are reproducing poor school performance and student background – being it gendered, ethnical or social – and hereby proving to the students, that school......Researching the pressing retention and dropout problems of the Danish VET system (app. 20 pct. of a year group never achieve an upper secondary education) this paper takes its point of departure in the hypothesis that low performing students are kept in a marginal position (at the risk of dropping...

  4. Hidden baryons: The physics of Compton composites

    Science.gov (United States)

    Mayer, Frederick J.

    2016-06-01

    A large fraction of the mass-energy of the Universe appears to be composed of Compton composites. How is it then that these composites are not frequently observed in experiments? This paper addresses this question, and others, by reviewing recent publications that: 1) introduced Compton composites, 2) showed how and where they are formed and 3) explained how they interact with other systems. Though ubiquitous in many physical situations, Compton composites are almost completely hidden in experiments due to their unique interaction characteristics. Still, their presence has been indirectly observed, though not interpreted as such until recently. Looking to the future, direct-detection experiments are proposed that could verify the composites' components. It is with deep sadness that I dedicate this paper to my mentor, collaborator, and friend, Dr. John R. Reitz, who passed away within days of the publication of our paper “Compton Composites Late in the Early Universe”.

  5. Hidden realities inside PBL design processes

    DEFF Research Database (Denmark)

    Pihl, Ole Verner

    2015-01-01

    Design Process, but is a group-based architecture and design education better than that which is individually based? How does PBL affect space, form, and creative processes? Hans Kiib, professor and one of the founders of the Department of Architecture and Design in Aalborg, describes his intentions...... within the group work, as it is closer related to the actual PBL process”. Is the Integrated Design Process (Knudstrup 2004) and is Colb (1975) still current and valid? Can we still use these methodologies when we must create “learning for an unknown future,” as Ronald Barnett (2004) claims that we...... investigates the creative processes of the collective and the individual and clarifies some of the hidden realities behind the PBL-based creative processes, both through an inquiry with the students and a more methodological and theoretical approach. The paper also explores how to integrate artistic...

  6. Aluminium Diphosphamethanides: Hidden Frustrated Lewis Pairs.

    Science.gov (United States)

    Styra, Steffen; Radius, Michael; Moos, Eric; Bihlmeier, Angela; Breher, Frank

    2016-07-04

    The synthesis and characterisation of two aluminium diphosphamethanide complexes, [Al(tBu)2 {κ(2) P,P'-Mes*PCHPMes*}] (3) and [Al(C6 F5 )2 {κ(2) P,P'-Mes*PCHPMes*}] (4), and the silylated analogue, Mes*PCHP(SiMe3 )Mes* (5), are reported. The aluminium complexes feature four-membered PCPAl core structures consisting of diphosphaallyl ligands. The silylated phosphine 5 was found to be a valuable precursor for the synthesis of 4 as it cleanly reacts with the diaryl aluminium chloride [(C6 F5 )2 AlCl]2 . The aluminium complex 3 reacts with molecular dihydrogen at room temperature under formation of the acyclic σ(2) λ(3) ,σ(3) λ(3) -diphosphine Mes*PCHP(H)Mes* and the corresponding dialkyl aluminium hydride [tBu2 AlH]3 . Thus, 3 belongs to the family of so-called hidden frustrated Lewis pairs.

  7. Wavelet domain hidden markovian bayesian document segmentation

    Institute of Scientific and Technical Information of China (English)

    Sun Junxi; Xiao Changyan; Zhang Su; Chen Yazhu

    2005-01-01

    A novel algorithm for Bayesian document segmentation is proposed based on the wavelet domain hidden Markov tree (HMT) model. Once the parameters of model are known, according to the sequential maximum a posterior probability (SMAP) rule, firstly, the likelihood probability of HMT model for each pattern is computed from fine to coarse procedure. Then, the interscale state transition probability is solved using Expectation Maximum (EM) algorithm based on hybrid-quadtree and multiscale context information is fused from coarse to fine procedure. In order to get pixellevel segmentation, the redundant wavelet domain Gaussian mixture model (GMM) is employed to formulate pixel-level statistical property. The experiment results show that the proposed scheme is feasible and robust.

  8. The Detection of Hidden Periodicities in EEG

    Institute of Scientific and Technical Information of China (English)

    YOU Rong-yi

    2007-01-01

    Abstract.A novel method for detecting the hidden periodicities in EEG is proposed.By using a width-varying window in the time domain, the structure function of EEG time series is defined. It is found that the minima of the structure function, within a finite window width, can be found regularly, which indicate that there are some certain periodicities associated with EEG time series. Based on the structure function, a further quadratic structure function of EEG time series is defined. By quadratic structure function, it can be seen that the periodicities of EEG become more obvious, moreover, the period of EEG can be determined accurately. These results will be meaningful for studying the neuron activity inside the human brain.

  9. Hidden fungi, emergent properties: endophytes and microbiomes.

    Science.gov (United States)

    Porras-Alfaro, Andrea; Bayman, Paul

    2011-01-01

    Endophytes are microorganisms that live within plant tissues without causing symptoms of disease. They are important components of plant microbiomes. Endophytes interact with, and overlap in function with, other core microbial groups that colonize plant tissues, e.g., mycorrhizal fungi, pathogens, epiphytes, and saprotrophs. Some fungal endophytes affect plant growth and plant responses to pathogens, herbivores, and environmental change; others produce useful or interesting secondary metabolites. Here, we focus on new techniques and approaches that can provide an integrative understanding of the role of fungal endophytes in the plant microbiome. Clavicipitaceous endophytes of grasses are not considered because they have unique properties distinct from other endophytes. Hidden from view and often overlooked, endophytes are emerging as their diversity, importance for plant growth and survival, and interactions with other organisms are revealed.

  10. A New Hidden Web Crawling Approach

    Directory of Open Access Journals (Sweden)

    L.Saoudi

    2015-10-01

    Full Text Available Traditional search engines deal with the Surface Web which is a set of Web pages directly accessible through hyperlinks and ignores a large part of the Web called hidden Web which is a great amount of valuable information of online database which is “hidden” behind the query forms. To access to those information the crawler have to fill the forms with a valid data, for this reason we propose a new approach which use SQLI technique in order to find the most promising keywords of a specific domain for automatic form submission. The effectiveness of proposed framework has been evaluated through experiments using real web sites and encouraging preliminary results were obtained

  11. Probabilistic Resilience in Hidden Markov Models

    Science.gov (United States)

    Panerati, Jacopo; Beltrame, Giovanni; Schwind, Nicolas; Zeltner, Stefan; Inoue, Katsumi

    2016-05-01

    Originally defined in the context of ecological systems and environmental sciences, resilience has grown to be a property of major interest for the design and analysis of many other complex systems: resilient networks and robotics systems other the desirable capability of absorbing disruption and transforming in response to external shocks, while still providing the services they were designed for. Starting from an existing formalization of resilience for constraint-based systems, we develop a probabilistic framework based on hidden Markov models. In doing so, we introduce two new important features: stochastic evolution and partial observability. Using our framework, we formalize a methodology for the evaluation of probabilities associated with generic properties, we describe an efficient algorithm for the computation of its essential inference step, and show that its complexity is comparable to other state-of-the-art inference algorithms.

  12. Identifying Exotic Hidden-Charm Pentaquarks.

    Science.gov (United States)

    Chen, Rui; Liu, Xiang; Li, Xue-Qian; Zhu, Shi-Lin

    2015-09-25

    The LHCb Collaboration at the Large Hadron Collider at CERN discovered two pentaquark states P_{c}(4380) and P_{c}(4450). These two hidden-charm states are interpreted as the loosely bound Σ_{c}(2455)D^{*} and Σ_{c}^{*}(2520)D^{*} molecular states in the boson exchange interaction model, which provides an explanation for why the experimental width of P_{c}(4450) is much narrower than that of P_{c}(4380). The discovery of the new resonances P_{c}(4380) and P_{c}(4450), indeed, opens a new page for hadron physics. The partners of P_{c}(4380) and P_{c}(4450) should be pursued in future experiments.

  13. Platform switching and bone platform switching.

    Science.gov (United States)

    Carinci, Francesco; Brunelli, Giorgio; Danza, Matteo

    2009-01-01

    Bone platform switching involves an inward bone ring in the coronal part of the implant that is in continuity with the alveolar bone crest. Bone platform switching is obtained by using a dental fixture with a reverse conical neck. A retrospective study was performed to evaluate the effectiveness of conventional vs reverse conical neck implants. In the period between May 2004 and November 2007, 86 patients (55 females and 31 males; median age, 53 years) were operated and 234 implants were inserted: 40 and 194 were conventional vs reverse conical neck implants, respectively. Kaplan-Meier algorithm and Cox regression were used to detect those variables associated with the clinical outcome. No differences in survival and success rates were detected between conventional vs reverse conical neck implants alone or in combination with any of the studied variables. Although bone platform switching leads to several advantages, no statistical difference in alveolar crest resorption is detected in comparison with reverse conical neck implants. We suppose that the proximity of the implant abutment junction to the alveolar crestal bone gives no protection against the microflora contained in the micrograph. Additional studies on larger series and a combination of platform switching and bone platform switching could lead to improved clinical outcomes.

  14. Platform development supportedby gaming

    DEFF Research Database (Denmark)

    Mikkola, Juliana Hsuan; Hansen, Poul H. Kyvsgård

    2007-01-01

    The challenge of implementing industrial platforms in practice can be described as a configuration problem caused by high number of variables, which often have contradictory influences on the total performance of the firm. Consequently, the specific platform decisions become extremely complex......, possibly increasing the strategic risks for the firm. This paper reports preliminary findings on platform management process at LEGO, a Danish toy company.  Specifically, we report the process of applying games combined with simulations and workshops in the platform development. We also propose a framework......, based on the portfolio management thinking, to measure the degree of modularity embedded in a given platform and to what extent it is aligned with other platforms....

  15. DFH-3 Satellite Platform

    Institute of Scientific and Technical Information of China (English)

    RenShufang

    2005-01-01

    The DFH-3 satellite platform is designed and developed by China Academy of Space Technology (CAST). It is a medium capability communications satellite platform. The platform adopts threeaxis attitude stabilization control system, having solar array output power of 1.7kW by the end of its design lifetime of 8 years. Its mass is 2100kg with payload capacity of 220kg.

  16. Product Platform Replacements

    DEFF Research Database (Denmark)

    Sköld, Martin; Karlsson, Christer

    2012-01-01

    Purpose – It is argued in this article that too little is known about product platforms and how to deal with them from a manager's point of view. Specifically, little information exists regarding when old established platforms are replaced by new generations in R&D and production environments...... originality and value is achieved by focusing on product platform replacements believed to represent a growing management challenge....

  17. Using HPGe detector for a solar hidden-photons search

    CERN Document Server

    Horvat, R; Krcmar, M; Krecak, Z; Ljubicic, A

    2012-01-01

    In this paper we report on the results of our search for photons from a U(1) gauge factor in the hidden sector of the full theory, by observing the single spectrum in a HPGe detector arising as a result of the photoelectric-like absorption of hidden photons emitted from the Sun on germanium atoms inside the detector. The main ingredient of the theory used in our analysis, a severely constrained kinetic mixing from the two U(1) gauge factors and massive hidden photons, leads to both photon into hidden states oscillations and to a minuscule coupling of hidden photons to visible matter, of which the latter our experimental setup has been designed to observe. On a theoretical side, full account was taken of the effects of refraction and damping of photons while propagating in the Sun's interior. We exclude hidden photons with kinetic couplings chi > (1.5x10^{-6}-2.6x10^{-11}) for the mass region 1.7x10^{-4} eV < m_\\gamma' < 3.4 eV. Our constraints on the mixing parameter chi at sub-eV hidden-photon masses p...

  18. The Creative Platform

    DEFF Research Database (Denmark)

    Byrge, Christian; Hansen, Søren

    This book is about introducing more creativity into general educational courses and cross-disciplinary activities. It is directed toward teachers at all levels in the educational system, but the Creative Platform is a general model, and thus the creative process will fundamentally be the same...... whether you consider thirdgrade teaching, human-resource development, or radical new thinking in product development in a company. The Creative Platform was developed at Aalborg University through a series of research-and-development activities in collaboration with educational institutions and private...... you can use in your work with the Creative Platform. This book is intended as an introduction on how to use the Creative Platform....

  19. Omnidirectional holonomic platforms

    Energy Technology Data Exchange (ETDEWEB)

    Pin, F.G.; Killough, S.M.

    1994-06-01

    This paper presents the concepts for a new family of wheeled platforms which feature full omnidirectionality with simultaneous and independently controlled rotational and translational motion capabilities. The authors first present the orthogonal-wheels concept and the two major wheel assemblies on which these platforms are based. They then describe how a combination of these assemblies with appropriate control can be used to generate an omnidirectional capability for mobile robot platforms. The design and control of two prototype platforms are then presented and their respective characteristics with respect to rotational and translational motion control are discussed.

  20. Hidden photon dark matter search with large metallic mirror

    Energy Technology Data Exchange (ETDEWEB)

    Doebrich, Babette; Lindner, Axel [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Daumiller, Kai; Engel, Ralph; Roth, Markus [Karlsruher Institut fuer Technologie (KIT), Karlsruhe (Germany); Kowalski, Marek [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Humboldt-Universitaet, Berlin (Germany). Inst. fuer Physik; Redondo, Javier [Zaragoza Univ. (Spain)

    2014-10-15

    If Dark Matter is composed of hidden-sector photons that kinetically mix with photons of the visible sector, then Dark Matter has a tiny oscillating electric field component. Its presence would lead to a small amount of visible radiation being emitted from a conducting surface, with the photon frequency given approximately by the mass of the hidden photon. Here, we report on experimental efforts that have started recently to search for such hidden photon Dark Matter in the (sub-)eV regime with a prototype mirror for the Auger fluorescence detector at the Karlsruhe Institute for Technology.

  1. Suppressing the QCD axion abundance by hidden monopoles

    Energy Technology Data Exchange (ETDEWEB)

    Kawasaki, Masahiro [Tokyo Univ., Chiba (Japan). Inst. for Cosmic Ray Research; Tokyo Univ., Chiba (Japan). Kavli IPMU (WPI), UTIAS; Takahashi, Fuminobu [Tokyo Univ., Miyagi (Japan). Dept. of Physics; Tokyo Univ., Chiba (Japan). Kavli IPMU (WPI), UTIAS; Yamada, Masaki [Tokyo Univ., Chiba (Japan). Inst. for Cosmic Ray Research; Tokyo Univ., Chiba (Japan). Kavli IPMU (WPI), UTIAS; DESY Hamburg (Germany)

    2015-11-15

    We study the Witten effect of hidden monopoles on the QCD axion dynamics, and show that its abundance as well as isocurvature perturbations can be significantly suppressed if there is a sufficient amount of hidden monopoles. When the hidden monopoles make up a significant fraction of dark matter, the Witten effect suppresses the abundance of axion with the decay constant smaller than 10{sup 12} GeV. The cosmological domain wall problem of the QCD axion can also be avoided, relaxing the upper bound on the decay constant when the Peccei-Quinn symmetry is spontaneously broken after inflation.

  2. Suppressing the QCD axion abundance by hidden monopoles

    Directory of Open Access Journals (Sweden)

    Masahiro Kawasaki

    2016-02-01

    Full Text Available We study the Witten effect of hidden monopoles on the QCD axion dynamics, and show that its abundance as well as isocurvature perturbations can be significantly suppressed if there is a sufficient amount of hidden monopoles. When the hidden monopoles make up a significant fraction of dark matter, the Witten effect suppresses the abundance of axion with the decay constant smaller than 1012GeV. The cosmological domain wall problem of the QCD axion can also be avoided, relaxing the upper bound on the decay constant when the Peccei–Quinn symmetry is spontaneously broken after inflation.

  3. Naturally light hidden photons in LARGE volume string compactifications

    Energy Technology Data Exchange (ETDEWEB)

    Goodsell, M. [LPTHE, Univ. Pierre et Marie Curie, Paris (France); Jaeckel, J. [Inst. for Particle Physics Phenomenology, Univ. Durham (United Kingdom); Redondo, J.; Ringwald, A. [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)

    2009-09-15

    Extra ''hidden'' U(1) gauge factors are a generic feature of string theory that is of particular phenomenological interest. They can kinetically mix with the Standard Model photon and are thereby accessible to a wide variety of astrophysical and cosmological observations and laboratory experiments. In this paper we investigate the masses and the kinetic mixing of hidden U(1)s in LARGE volume compactifications of string theory. We find that in these scenarios the hidden photons can be naturally light and that their kinetic mixing with the ordinary electromagnetic photon can be of a size interesting for near future experiments and observations. (orig.)

  4. Advanced offshore oil platforms

    Energy Technology Data Exchange (ETDEWEB)

    Ellers, F.S.

    1982-04-01

    Four innovative offshore platforms that are designed to withstand 100-foot waves in waters 600-feet deep are described. These platforms are: (1) Stratfjord B Concrete Gravity-Base Platform; (2) Magnus Steel-Template-Jacket Platform; (3) Hutton Tension-Leg Platform; and (4) Block 280 Guyed Tower. The Statfjord B platform, designed in Norway, rests on four massive concrete columns with storage tanks at the base. It depends solely on its own mass for stability. The Magnus platform, designed by the British, is the heaviest offshore platform yet fabricated, weighing 41,000 tons. Two of the platform's four legs will incorporate flotation chambers so that the structure can be floated to its site in the North Sea. The Hutton structure, also designed in England, will consist of a buoyant hull tethered to the sea floor by slender steel tubes at its four corners. The first platform of its type, the Hutton structure is also destined for the North Sea. The US designed Block 280 guyed tower is designed for service in the Gulf of Mexico in water 1000 feet deep. It will be pinned to the sea floor by a spokelike array of 20 steel cables, each one more than 3000 feet long. The tower and its guys will weigh 43,000 tons, slightly more than the Magnus steel-template jacket and more than four time as much as the Eiffel Tower. At a cost of approximately $2.6 billion, the Magnus is the most expensive offshore platform to date. The Statfjord B was put into production in 1982. The Magnus is scheduled for oil production in 1983. The Hutton and the Block 280 will both be producing in 1984. (JMT)

  5. EURESCOM Services Platform

    NARCIS (Netherlands)

    Nieuwenhuis, Lambertus Johannes Maria; van Halteren, Aart

    1999-01-01

    This paper presents the results of the EURESCOM Project 715. In February 1999, a large team of researchers from six European public network operators completed a two year period of cooperative experiments on a TINA-based environment, called the EURESCOM Services Platform (ESP). This platform

  6. Photoproduction of hidden-charm states in the reaction near threshold

    Science.gov (United States)

    Huang, Yin; Xie, Ju-Jun; He, Jun; Chen, Xurong; Zhang, Hong-Fei

    2016-12-01

    We report on a theoretical study of the hidden charm states in the reaction near threshold within an effective Lagrangian approach. In addition to the contributions from the s-channel nucleon pole, the t-channel D0 exchange, the u-channel exchange and the contact term, we study the contributions from the states with spin-parity JP = 1/2- and 3/2-. The total and differential cross sections of the reaction are predicted. It is found that the contributions of these states give clear peak structures in the total cross sections. Thus, this reaction is another new platform to study the hidden-charm states. It is expected that our model calculation may be tested by future experiments. Supported by Major State Basic Research Development Program in China (2014CB845400), National Natural Science Foundation of China (11475227, 11275235, 11035006) and Chinese Academy of Sciences (Knowledge Innovation Project (KJCX2-EW-N01), Youth Innovation Promotion Association CAS (2016367), Open Project Program of State Key Laboratory of Theoretical Physics, Institute of Theoretical Physics, Chinese Academy of Sciences, China (Y5KF151CJ1)

  7. Hidden markov model for the prediction of transmembrane proteins using MATLAB.

    Science.gov (United States)

    Chaturvedi, Navaneet; Shanker, Sudhanshu; Singh, Vinay Kumar; Sinha, Dhiraj; Pandey, Paras Nath

    2011-01-01

    Since membranous proteins play a key role in drug targeting therefore transmembrane proteins prediction is active and challenging area of biological sciences. Location based prediction of transmembrane proteins are significant for functional annotation of protein sequences. Hidden markov model based method was widely applied for transmembrane topology prediction. Here we have presented a revised and a better understanding model than an existing one for transmembrane protein prediction. Scripting on MATLAB was built and compiled for parameter estimation of model and applied this model on amino acid sequence to know the transmembrane and its adjacent locations. Estimated model of transmembrane topology was based on TMHMM model architecture. Only 7 super states are defined in the given dataset, which were converted to 96 states on the basis of their length in sequence. Accuracy of the prediction of model was observed about 74 %, is a good enough in the area of transmembrane topology prediction. Therefore we have concluded the hidden markov model plays crucial role in transmembrane helices prediction on MATLAB platform and it could also be useful for drug discovery strategy. The database is available for free at bioinfonavneet@gmail.comvinaysingh@bhu.ac.in.

  8. Isovector and hidden-beauty partners of the X(3872)

    Energy Technology Data Exchange (ETDEWEB)

    Høgaasen, Hallstein, E-mail: hallstein.hogasen@fys.uio.no [Department of Physics, University of Oslo, Box 1048, NO-0316 Oslo (Norway); Kou, Emi, E-mail: kou@lal.in2p3.fr [Laboratoire de l' Accélérateur Linéaire, Université Paris-Sud, IN2P3-CNRS, Centre Scientifique d' Orsay, 91898 Orsay Cedex (France); Richard, Jean-Marc, E-mail: j-m.richard@ipnl.in2p3.fr [Université de Lyon, Institut de Physique Nucléaire de Lyon, UCBL–IN2P3-CNRS, 4, rue Enrico Fermi, 69622 Villeurbanne Cedex (France); Sorba, Paul, E-mail: paul.sorba@lapth.cnrs.fr [LAPTh, Laboratoire d' Annecy-le-Vieux de Physique Théorique, CNRS, Université de Savoie, BP 110, 74941 Annecy-le-Vieux Cedex (France)

    2014-05-01

    The isovector partners of the X(3872), recently found at BES III, Belle and CLEO-c were predicted in a simple model based on the chromomagnetic interaction among quarks. The extension to the hidden-beauty sector is discussed.

  9. Local clustering in scale-free networks with hidden variables.

    Science.gov (United States)

    van der Hofstad, Remco; Janssen, A J E M; van Leeuwaarden, Johan S H; Stegehuis, Clara

    2017-02-01

    We investigate the presence of triangles in a class of correlated random graphs in which hidden variables determine the pairwise connections between vertices. The class rules out self-loops and multiple edges. We focus on the regime where the hidden variables follow a power law with exponent τ∈(2,3), so that the degrees have infinite variance. The natural cutoff h_{c} characterizes the largest degrees in the hidden variable models, and a structural cutoff h_{s} introduces negative degree correlations (disassortative mixing) due to the infinite-variance degrees. We show that local clustering decreases with the hidden variable (or degree). We also determine how the average clustering coefficient C scales with the network size N, as a function of h_{s} and h_{c}. For scale-free networks with exponent 2vanish only for networks as large as N=10^{9}.

  10. A Bell-type Theorem Without Hidden Variables

    CERN Document Server

    Stapp, Henry P

    2002-01-01

    Bell's theorem rules out local hidden-variable theories. The locality condition is the demand that what an experimenter freely chooses to measure in one space-time region has no influence in a second space-time region that is spacelike separated from the first. The hidden-variable stipulation means that this demand is implemented through requirements on an assumed-to-exist substructure involving hidden variables. The question thus arises whether the locality condition itself fails, or only its implementation by means of the assumed hidden-variable structure. This paper shows that any theory that satisfies two generally accepted features of orthodox quantum theory and that yields certain predictions of quantum theory cannot satisfy the afore-mentioned locality condition. These two features are that the choices made by the experimenters can be treated as localized free variables and that such free choices do not affect outcomes that have already occurred.

  11. Modelling proteins' hidden conformations to predict antibiotic resistance

    Science.gov (United States)

    Hart, Kathryn M.; Ho, Chris M. W.; Dutta, Supratik; Gross, Michael L.; Bowman, Gregory R.

    2016-10-01

    TEM β-lactamase confers bacteria with resistance to many antibiotics and rapidly evolves activity against new drugs. However, functional changes are not easily explained by differences in crystal structures. We employ Markov state models to identify hidden conformations and explore their role in determining TEM's specificity. We integrate these models with existing drug-design tools to create a new technique, called Boltzmann docking, which better predicts TEM specificity by accounting for conformational heterogeneity. Using our MSMs, we identify hidden states whose populations correlate with activity against cefotaxime. To experimentally detect our predicted hidden states, we use rapid mass spectrometric footprinting and confirm our models' prediction that increased cefotaxime activity correlates with reduced Ω-loop flexibility. Finally, we design novel variants to stabilize the hidden cefotaximase states, and find their populations predict activity against cefotaxime in vitro and in vivo. Therefore, we expect this framework to have numerous applications in drug and protein design.

  12. Recent Applications of Hidden Markov Models in Computational Biology

    Institute of Scientific and Technical Information of China (English)

    Khar Heng Choo; Joo Chuan Tong; Louxin Zhang

    2004-01-01

    This paper examines recent developments and applications of Hidden Markov Models (HMMs) to various problems in computational biology, including multiple sequence alignment, homology detection, protein sequences classification, and genomic annotation.

  13. Self-similarity of complex networks and hidden metric spaces

    CERN Document Server

    Serrano, M Angeles; Boguna, Marian

    2007-01-01

    We demonstrate that the self-similarity of some scale-free networks with respect to a simple degree-thresholding renormalization scheme finds a natural interpretation in the assumption that network nodes exist in hidden metric spaces. Clustering, i.e., cycles of length three, plays a crucial role in this framework as a topological reflection of the triangle inequality in the hidden geometry. We prove that a class of hidden variable models with underlying metric spaces are able to accurately reproduce the self-similarity properties that we measured in the real networks. Our findings indicate that hidden geometries underlying these real networks are a plausible explanation for their observed topologies and, in particular, for their self-similarity with respect to the degree-based renormalization.

  14. Search for hidden particles with the SHiP experiment

    Energy Technology Data Exchange (ETDEWEB)

    Hagner, Caren; Bick, Daniel; Bieschke, Stefan; Ebert, Joachim; Schmidt-Parzefall, Walter [Universitaet Hamburg, Institut fuer Experimentalphysik, Luruper Chaussee 149, 22761 Hamburg (Germany)

    2016-07-01

    Many theories beyond the standard model predict long lived neutral (hidden) particles. There might be a whole Hidden Sector (HS) of weakly interacting particles, which cannot be detected in existing high energy experiments. The SHiP experiment (Search for Hidden Particles) requires a high intensity beam dump, which could be realized by a new facility at the CERN SPS accelerator. New superweakly interacting particles with masses below O(10) GeV could be produced in the beam dump and detected in a general purpose Hidden Sector (HS) detector. In addition there will be a dedicated tau neutrino subdetector. I present the major requirements and technical challenges for the HS detector and discuss how the HS can be accessed through several portals: neutrino portal, scalar portal, vector portal and many more.

  15. Dark matter in the nonabelian hidden gauge theory

    CERN Document Server

    Yamanaka, Nodoka; Gongyo, Shinya; Iida, Hideaki

    2015-01-01

    We discuss the dark matter in the hidden gauge theory. We propose a scenario where the mini-inflation dilutes the dark matter density. This scenario is consistent with the current baryon number asymmetry.

  16. Hidden phase in a two-dimensional Sn layer stabilized by modulation hole doping

    Science.gov (United States)

    Ming, Fangfei; Mulugeta, Daniel; Tu, Weisong; Smith, Tyler S.; Vilmercati, Paolo; Lee, Geunseop; Huang, Ying-Tzu; Diehl, Renee D.; Snijders, Paul C.; Weitering, Hanno H.

    2017-03-01

    Semiconductor surfaces and ultrathin interfaces exhibit an interesting variety of two-dimensional quantum matter phases, such as charge density waves, spin density waves and superconducting condensates. Yet, the electronic properties of these broken symmetry phases are extremely difficult to control due to the inherent difficulty of doping a strictly two-dimensional material without introducing chemical disorder. Here we successfully exploit a modulation doping scheme to uncover, in conjunction with a scanning tunnelling microscope tip-assist, a hidden equilibrium phase in a hole-doped bilayer of Sn on Si(111). This new phase is intrinsically phase separated into insulating domains with polar and nonpolar symmetries. Its formation involves a spontaneous symmetry breaking process that appears to be electronically driven, notwithstanding the lack of metallicity in this system. This modulation doping approach allows access to novel phases of matter, promising new avenues for exploring competing quantum matter phases on a silicon platform.

  17. Mapping of the photo-induced metastable and hidden phases in 2D electronic materials

    Science.gov (United States)

    Zhou, Faran; Sun, Tianyin; Han, Tzong-Ru; Malliakas, Christos; Duxbury, Phillip; Mahanti, Subhendra; Kanatzidis, Mercouri; Ruan, Chong-Yu; MSU Team; NU Team

    Using the ultrafast electron imaging techniques, we studied the light-induced phase transitions in transition-metal dichalcogenide materials. A succession of different phases was introduced transiently using femtosecond mid-infrared pulses and the local atomic scale charge-density-wave dynamics and morphological evolution of the long-range textured domains were in situ characterized using the ultrashort coherent electron pulses. The various metastable and hidden states emerging under the controlled nonthermal, nonadiabatic driving highlight the interaction-driven nature of these transitions with limited involvement of lattice entropy. The methodology introduced here can be generally applied to survey the complex energy landscape in strongly correlated electron systems, avoiding the difficulty of electrostatic gating or confounding effects due to defects and/or disorder. In particular, the observation of robust non-thermal switching at meso-scales and at ultrafast timescales, provides a platform for designing high-speed low-energy consumption nano-photonics and electronics devices.

  18. Hidden Symmetry from Supersymmetry in One-Dimensional Quantum Mechanics

    Directory of Open Access Journals (Sweden)

    Alexander A. Andrianov

    2009-06-01

    Full Text Available When several inequivalent supercharges form a closed superalgebra in Quantum Mechanics it entails the appearance of hidden symmetries of a Super-Hamiltonian. We examine this problem in one-dimensional QM for the case of periodic potentials and potentials with finite number of bound states. After the survey of the results existing in the subject the algebraic and analytic properties of hidden-symmetry differential operators are rigorously elaborated in the Theorems and illuminated by several examples.

  19. Stabilization of stochastic systems with hidden Markovian jumps

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    This paper considers the adaptive control of discrete-time hybrid stochastic systems with unknown randomly jumping parameters described by a finite-state hidden Markov chain. An intuitive yet longstanding conjecture in this area is that such hybrid systems can be adaptively stabilized whenever the rate of transition of the hidden Markov chain is small enough. This paper provides a rigorous positive answer to this conjecture by establishing the global stability of a gradient-algorithm-based adaptive linear-quadratic control.

  20. Extracting hidden trails and roads under canopy using LIDAR

    OpenAIRE

    Krougios, Prokopios

    2008-01-01

    The field of Remote Sensing has been greatly benefited by the development of LIDAR. The extraction of bare earth under tree canopies and especially the identification of hidden trails are important tools for military and civilian operations in dense forests. LIDAR data from Sequoia National Park in California (2008) and Fort Belvoir Military Base in Virginia (2007) were two areas that were selected for analysis. Quick Terrain Modeler software was used in order to recognize hidden trails....

  1. Physical nature of a hidden mass in the Universe

    Energy Technology Data Exchange (ETDEWEB)

    Doroshkevich, A.G.; Khlopov, M.Yu. (AN SSSR, Moscow. Inst. Prikladnoj Matematiki)

    1984-04-01

    The problem of an origin of the hidden mass of the Universe is discussed. Observation astronomic data on large-scale Universe structure and hidden mass distribution within the framework of the adiabatic theory of galaxies formation point out the dominance in nowadays Universe of weakly-interacting particles with 15-60 eV mass. Restrictions are obtained for a possible admixture of other relict particles.

  2. Hidden Markov Models with Factored Gaussian Mixtures Densities

    Institute of Scientific and Technical Information of China (English)

    LI Hao-zheng; LIU Zhi-qiang; ZHU Xiang-hua

    2004-01-01

    We present a factorial representation of Gaussian mixture models for observation densities in Hidden Markov Models(HMMs), which uses the factorial learning in the HMM framework. We derive the reestimation formulas for estimating the factorized parameters by the Expectation Maximization (EM) algorithm. We conduct several experiments to compare the performance of this model structure with Factorial Hidden Markov Models(FHMMs) and HMMs, some conclusions and promising empirical results are presented.

  3. Aligning the Hidden Curriculum of Management Education With PRME

    DEFF Research Database (Denmark)

    Blasco, Maribel

    2012-01-01

    This article argues that mainstreaming responsible management education in line with the Principles of Responsible Management Education (PRME) requires close attention to the hidden curriculum (HC), that is, the implicit dimensions of educational experiences. Altering formal curricular goals...... combined with transformative learning and communities of practice theory, the article offers an inquiry-based framework for PRME implementation that takes these moral learning and socialization processes into account. It provides suggestions for how to address the hidden curriculum both in the diagnostic...

  4. Reduced-Rank Hidden Markov Models

    CERN Document Server

    Siddiqi, Sajid M; Gordon, Geoffrey J

    2009-01-01

    We introduce the Reduced-Rank Hidden Markov Model (RR-HMM), a generalization of HMMs that can model smooth state evolution as in Linear Dynamical Systems (LDSs) as well as non-log-concave predictive distributions as in continuous-observation HMMs. RR-HMMs assume an m-dimensional latent state and n discrete observations, with a transition matrix of rank k <= m. This implies the dynamics evolve in a k-dimensional subspace, while the shape of the set of predictive distributions is determined by m. Latent state belief is represented with a k-dimensional state vector and inference is carried out entirely in R^k, making RR-HMMs as computationally efficient as k-state HMMs yet more expressive. To learn RR-HMMs, we relax the assumptions of a recently proposed spectral learning algorithm for HMMs (Hsu, Kakade and Zhang 2009) and apply it to learn k-dimensional observable representations of rank-k RR-HMMs. The algorithm is consistent and free of local optima, and we extend its performance guarantees to cover the RR-...

  5. Search algorithms, hidden labour and information control

    Directory of Open Access Journals (Sweden)

    Paško Bilić

    2016-06-01

    Full Text Available The paper examines some of the processes of the closely knit relationship between Google’s ideologies of neutrality and objectivity and global market dominance. Neutrality construction comprises an important element sustaining the company’s economic position and is reflected in constant updates, estimates and changes to utility and relevance of search results. Providing a purely technical solution to these issues proves to be increasingly difficult without a human hand in steering algorithmic solutions. Search relevance fluctuates and shifts through continuous tinkering and tweaking of the search algorithm. The company also uses third parties to hire human raters for performing quality assessments of algorithmic updates and adaptations in linguistically and culturally diverse global markets. The adaptation process contradicts the technical foundations of the company and calculations based on the initial Page Rank algorithm. Annual market reports, Google’s Search Quality Rating Guidelines, and reports from media specialising in search engine optimisation business are analysed. The Search Quality Rating Guidelines document provides a rare glimpse into the internal architecture of search algorithms and the notions of utility and relevance which are presented and structured as neutral and objective. Intertwined layers of ideology, hidden labour of human raters, advertising revenues, market dominance and control are discussed throughout the paper.

  6. A hidden classical symmetry of QCD

    CERN Document Server

    Glozman, L Ya

    2016-01-01

    The classical part of the QCD partition function (the integrand) has, ignoring irrelevant exact zero modes of the Dirac operator, a local SU(2N_F) \\supset SU(N_F)_L \\times SU(N_F)_R \\times U(1)_A symmetry which is absent at the Lagrangian level. This symmetry is broken anomalously and spontaneously. Effects of spontaneous breaking of chiral symmetry are contained in the near-zero modes of the Dirac operator. If physics of anomaly is also encoded in the same near-zero modes, then their truncation on the lattice should recover a hidden classical SU(2N_F) symmetry in correlators and spectra. This naturally explains observation on the lattice of a large degeneracy of hadrons, that is higher than the SU(N_F)_L \\times SU(N_F)_R \\times U(1)_A chiral symmetry, upon elimination by hands of the lowest-lying modes of the Dirac operator. We also discuss an implication of this symmetry for the high temperature QCD.

  7. Seiberg duality versus hidden local symmetry

    CERN Document Server

    Abel, Steven

    2012-01-01

    It is widely believed that the emergent magnetic gauge symmetry of SQCD is analogous to a hidden local symmetry (HLS). We explore this idea in detail, deriving the entire (spontaneously broken) magnetic theory by applying the HLS formalism to spontaneously broken SU(N) SQCD. We deduce the K\\"ahler potential in the HLS description, and show that gauge and flavour symmetry are smoothly restored along certain scaling directions in moduli space. We propose that it is these symmetry restoring directions, associated with the R-symmetry of the theory, that allow full Seiberg duality. Reconsidering the origin of the magnetic gauge bosons as the rho-mesons of the electric theory, colour-flavour locking allows a simple determination of the parameter "a". Its value continuously interpolates between a=2 on the baryonic branch of moduli space - corresponding to "vector meson dominance" - and a=1 on the mesonic branch. Both limiting values are consistent with previous results in the literature. The HLS formalism is further...

  8. Natural inflation with hidden scale invariance

    Directory of Open Access Journals (Sweden)

    Neil D. Barrie

    2016-05-01

    Full Text Available We propose a new class of natural inflation models based on a hidden scale invariance. In a very generic Wilsonian effective field theory with an arbitrary number of scalar fields, which exhibits scale invariance via the dilaton, the potential necessarily contains a flat direction in the classical limit. This flat direction is lifted by small quantum corrections and inflation is realised without need for an unnatural fine-tuning. In the conformal limit, the effective potential becomes linear in the inflaton field, yielding to specific predictions for the spectral index and the tensor-to-scalar ratio, being respectively: ns−1≈−0.025(N⋆60−1 and r≈0.0667(N⋆60−1, where N⋆≈30–65 is a number of efolds during observable inflation. This predictions are in reasonable agreement with cosmological measurements. Further improvement of the accuracy of these measurements may turn out to be critical in falsifying our scenario.

  9. Search algorithms, hidden labour and information control

    Directory of Open Access Journals (Sweden)

    Paško Bilić

    2016-06-01

    Full Text Available The paper examines some of the processes of the closely knit relationship between Google’s ideologies of neutrality and objectivity and global market dominance. Neutrality construction comprises an important element sustaining the company’s economic position and is reflected in constant updates, estimates and changes to utility and relevance of search results. Providing a purely technical solution to these issues proves to be increasingly difficult without a human hand in steering algorithmic solutions. Search relevance fluctuates and shifts through continuous tinkering and tweaking of the search algorithm. The company also uses third parties to hire human raters for performing quality assessments of algorithmic updates and adaptations in linguistically and culturally diverse global markets. The adaptation process contradicts the technical foundations of the company and calculations based on the initial Page Rank algorithm. Annual market reports, Google’s Search Quality Rating Guidelines, and reports from media specialising in search engine optimisation business are analysed. The Search Quality Rating Guidelines document provides a rare glimpse into the internal architecture of search algorithms and the notions of utility and relevance which are presented and structured as neutral and objective. Intertwined layers of ideology, hidden labour of human raters, advertising revenues, market dominance and control are discussed throughout the paper.

  10. Natural Inflation with Hidden Scale Invariance

    CERN Document Server

    Barrie, Neil D; Liang, Shelley

    2016-01-01

    We propose a new class of natural inflation models based on a hidden scale invariance. In a very generic Wilsonian effective field theory with an arbitrary number of scalar fields, which exhibits scale invariance via the dilaton, the potential necessarily contains a flat direction in the classical limit. This flat direction is lifted by small quantum corrections and inflation is realised without need for an unnatural fine-tuning. In the conformal limit, the effective potential becomes linear in the inflaton field, yielding to specific predictions for the spectral index and the tensor-to-scalar ratio, being respectively: $n_s-1\\approx 0.025\\left(\\frac{N_{\\star}}{60}\\right)^{-1}$ and $r\\approx 0.0667\\left(\\frac{N_{\\star}}{60}\\right)^{-1}$, where $N_{\\star}\\approx 30-65$ is a number of efolds during observable inflation. This predictions are in reasonable agreement with cosmological measurements. Further improvement of the accuracy of these measurements may turn out to be critical in falsifying our scenario.

  11. Hidden Markov models in automatic speech recognition

    Science.gov (United States)

    Wrzoskowicz, Adam

    1993-11-01

    This article describes a method for constructing an automatic speech recognition system based on hidden Markov models (HMMs). The author discusses the basic concepts of HMM theory and the application of these models to the analysis and recognition of speech signals. The author provides algorithms which make it possible to train the ASR system and recognize signals on the basis of distinct stochastic models of selected speech sound classes. The author describes the specific components of the system and the procedures used to model and recognize speech. The author discusses problems associated with the choice of optimal signal detection and parameterization characteristics and their effect on the performance of the system. The author presents different options for the choice of speech signal segments and their consequences for the ASR process. The author gives special attention to the use of lexical, syntactic, and semantic information for the purpose of improving the quality and efficiency of the system. The author also describes an ASR system developed by the Speech Acoustics Laboratory of the IBPT PAS. The author discusses the results of experiments on the effect of noise on the performance of the ASR system and describes methods of constructing HMM's designed to operate in a noisy environment. The author also describes a language for human-robot communications which was defined as a complex multilevel network from an HMM model of speech sounds geared towards Polish inflections. The author also added mandatory lexical and syntactic rules to the system for its communications vocabulary.

  12. Stochastic precipitation generator with hidden state covariates

    Science.gov (United States)

    Kim, Yongku; Lee, GyuWon

    2017-08-01

    Time series of daily weather such as precipitation, minimum temperature and maximum temperature are commonly required for various fields. Stochastic weather generators constitute one of the techniques to produce synthetic daily weather. The recently introduced approach for stochastic weather generators is based on generalized linear modeling (GLM) with covariates to account for seasonality and teleconnections (e.g., with the El Niño). In general, stochastic weather generators tend to underestimate the observed interannual variance of seasonally aggregated variables. To reduce this overdispersion, we incorporated time series of seasonal dry/wet indicators in the GLM weather generator as covariates. These seasonal time series were local (or global) decodings obtained by a hidden Markov model of seasonal total precipitation and implemented in the weather generator. The proposed method is applied to time series of daily weather from Seoul, Korea and Pergamino, Argentina. This method provides a straightforward translation of the uncertainty of the seasonal forecast to the corresponding conditional daily weather statistics.

  13. Academic mobbing: hidden health hazard at workplace.

    Science.gov (United States)

    Khoo, Sb

    2010-01-01

    Academic mobbing is a non-violent, sophisticated, 'ganging up' behaviour adopted by academicians to "wear and tear" a colleague down emotionally through unjustified accusation, humiliation, general harassment and emotional abuse. These are directed at the target under a veil of lies and justifications so that they are "hidden" to others and difficult to prove. Bullies use mobbing activities to hide their own weaknesses and incompetence. Targets selected are often intelligent, innovative high achievers, with good integrity and principles. Mobbing activities appear trivial and innocuous on its own but the frequency and pattern of their occurrence over long period of time indicates an aggressive manipulation to "eliminate" the target. Mobbing activities typically progress through five stereotypical phases that begins with an unsolved minor conflict between two workers and ultimately escalates into a senseless mobbing whereby the target is stigmatized and victimized to justify the behaviours of the bullies. The result is always physical, mental, social distress or illness and, most often, expulsion of target from the workplace. Organizations are subjected to great financial loss, loss of key workers and a tarnished public image and reputation. Public awareness, education, effective counselling, establishment of anti-bullying policies and legislations at all levels are necessary to curb academic mobbing. General practitioners (GPs) play an important role in supporting patients subjected to mental and physical health injury caused by workplace bullying and mobbing.

  14. Coulomb gauge model for hidden charm tetraquarks

    Science.gov (United States)

    Xie, W.; Mo, L. Q.; Wang, Ping; Cotanch, Stephen R.

    2013-08-01

    The spectrum of tetraquark states with hidden charm is studied within an effective Coulomb gauge Hamiltonian approach. Of the four independent color schemes, two are investigated, the (qcbar)1(cqbar)1 singlet-singlet (molecule) and the (qc)3(qbarcbar)3 triplet-triplet (diquark), for selected JPC states using a variational method. The predicted masses of triplet-triplet tetraquarks are roughly a GeV heavier than the singlet-singlet states. There is also an interesting flavor dependence with (qqbar)1 (ccbar1) states about half a GeV lighter than (qcbar)1(qbarc)1. The lightest 1++ and 1-- predictions are in agreement with the observed X (3872) and Y (4008) masses suggesting they are molecules with ωJ / ψ and ηhc, rather than D*Dbar* and DDbar, type structure, respectively. Similarly, the lightest isovector 1++ molecule, having a ρJ / ψ flavor composition, has mass near the recently observed charged Zc (3900) value. These flavor configurations are consistent with observed X, Y and Zc decays to ππJ / ψ.

  15. Hidden topological angles and Lefschetz thimbles

    CERN Document Server

    Behtash, Alireza; Schaefer, Thomas; Unsal, Mithat

    2015-01-01

    We demonstrate the existence of hidden topological angles (HTAs) in a large class of quantum field theories and quantum mechanical systems. HTAs are distinct from theta-parameters in the lagrangian. They arise as invariant angle associated with saddle points of the complexified path integral and their descent manifolds (Lefschetz thimbles). Physical effects of HTAs become most transparent upon analytic continuation in $n_f$ to non-integer number of flavors, reducing in the integer $n_f$ limit to a $\\mathbb Z_2$ valued phase difference between dominant saddles. In ${\\cal N}=1$ super Yang-Mills theory we demonstrate the microscopic mechanism for the vanishing of the gluon condensate. The same effect leads to an anomalously small condensate in a QCD-like $SU(N)$ gauge theory with fermions in the two-index representation. The basic phenomenon is that, contrary to folklore, the gluon condensate can receive both positive and negative contributions in a semi-classical expansion. In quantum mechanics, a HTA leads to ...

  16. Detecting hidden sources-STUK/HUT team

    Energy Technology Data Exchange (ETDEWEB)

    Nikkinen, M.; Aarnio, P. [Helsinki Univ. of Technology, Espoo (Finland); Honkamaa, T.; Tiilikainen, H. [Finnish Centre for Radiation and Nuclear Safety, Helsinki (Finland)

    1997-12-31

    The task of the team was to locate and to identify hidden sources in a specified area in Padasjoki Auttoinen village. The team used AB-420 helicopter of the Finnish Frontier Guard. The team had two measuring systems: HPGe system (relative efficiency 18%) and 5`x5` NaI system. The team found two sources in real-time and additional two sources after 24 h analysis time. After the locations and characteristics of the sources were announced it was found out that altogether six sources would have been possible to find using the measured data. The total number of sources was ten. The NaI detector was good at detecting and locating the sources and HPGe was most useful in identification and calculation of the activity estimates. The following development should be made: 1) larger detectors are needed, 2) the software has to be improved. (This has been performed after the exercise) and 3) the navigation must be based on DGPS. visual navigation causes easily gaps between the flight lines and some sources may not be detected. (au).

  17. Hidden Web Data Extraction Using Dynamic Rule Generation

    Directory of Open Access Journals (Sweden)

    Anuradha

    2011-08-01

    Full Text Available World Wide Web is a global information medium of interlinked hypertext documents accessed via computers connected to the internet. Most of the users rely on traditional search engines to search theinformation on the web. These search engines deal with the Surface Web which is a set of Web pages directly accessible through hyperlinks and ignores a large part of the Web called Hidden Web which is hidden to present-day search engines. It lies behind search forms and this part of the web containing an almost endless amount of sources providing high quality information stored in specialized databases can be found in the depths of the WWW. A large amount of this Hidden web is structured i.e Hidden websites contain the information in the form of lists and tables. However visiting dozens of these sites and analyzing the results is very much time consuming task for user. Hence, it is desirable to build a prototype which will minimize user’s effort and give him high quality information in integrated form. This paper proposes a novel method that extracts the data records from the lists and tables of various hidden web sites of same domain using dynamic rule generation and forms a repository which is used for later searching. By searching the data from this repository, user will find the desired data at one place. It reduces the user’s effort to look at various result pages of different hidden websites.

  18. Market-oriented management method of coalmine accident hidden dangers

    Institute of Scientific and Technical Information of China (English)

    LIU Zhao-xia; LI Xing-dong; LU Ying; REN Da-wei

    2007-01-01

    By analyzing the problems which exist currently in the accident hidden dangers management of the coal mine, this paper proposed a new kind of management method-"simulating the market", in which an operation pattern of simulating the market to transact hidden troubles was constructed. This method introduces "Market Mechanism"into safe management, and adopts measurable value to describe the hidden dangers such as" human behavior, technique, environment, equipments etc.". It regards the hidden dangers as "the goods produced by labor" which are found out by the safety managers and the security inspectors, then sells as "commodity". By the process of disposing, counterchecking, re-selling, and redisposing. It forms a set of market-oriented closed-form management pattern of coalmine accident hidden dangers. This kind of management method changes the past traditional methods in which the wageworkers treat safety management passively, but to encourage and restrict them to participate in the check-up and improvement of the hidden dangers.

  19. QCD sum rule study of hidden-charm pentaquarks

    CERN Document Server

    Chen, Hua-Xing; Chen, Wei; Steele, T G; Liu, Xiang; Zhu, Shi-Lin

    2016-01-01

    We study the mass spectra of hidden-charm pentaquarks having spin $J = {1\\over2},{3\\over2},{5\\over2}$ and quark contents $uud c \\bar c$. We systematically construct all the relevant local hidden-charm pentaquark currents, and select some of them to perform QCD sum rule analyses. We find that the $P_c(4380)$ and $P_c(4450)$ can be identified as hidden-charm pentaquark states composed of an anti-charmed meson and a charmed baryon. We also find the lowest-lying hidden-charm $J^P = 1/2^-$ pentaquark state of mass $4.33^{+0.17}_{-0.13}$ GeV, while the $J^P = 1/2^+$ mass prediction of 4.7--4.9 GeV is significantly higher. Similarly, the lowest-lying hidden-charm $J^P = 3/2^-$ pentaquark state mass is $4.37^{+0.18}_{-0.13}$ GeV, consistent with the $J^P = 3/2^-$ $P_c(4380)$, while the $J^P = 3/2^+$ is also significantly higher with a mass above 4.6 GeV. The hidden-charm $J^P = 5/2^-$ pentaquark state mass is 4.5--4.6 GeV, slightly larger than the $J^P = 5/2^+$ $P_c(4450)$.

  20. The Common HOL Platform

    OpenAIRE

    Adams, Mark

    2015-01-01

    The Common HOL project aims to facilitate porting source code and proofs between members of the HOL family of theorem provers. At the heart of the project is the Common HOL Platform, which defines a standard HOL theory and API that aims to be compatible with all HOL systems. So far, HOL Light and hol90 have been adapted for conformance, and HOL Zero was originally developed to conform. In this paper we provide motivation for a platform, give an overview of the Common HOL Platform's theory and...

  1. Ladder attachment platform

    Science.gov (United States)

    Swygert,; Richard, W [Springfield, SC

    2012-08-28

    A ladder attachment platform is provided that includes a base for attachment to a ladder that has first and second side rails and a plurality of rungs that extend between in a lateral direction. Also included is a user platform for having a user stand thereon that is carried by the base. The user platform may be positioned with respect to the ladder so that it is not located between a first plane that extends through the first side rail and is perpendicular to the lateral direction and a second plane that extends through the second side rail and is perpendicular to the lateral direction.

  2. Was ist das Hidden Web? Die Entstehung, Eigenschaften und gesellschaftliche Bedeutung von anonymer Kommunikation im Hidden Web.

    OpenAIRE

    Papsdorf, Christian

    2016-01-01

    More than two-and-a-half million people currently use the Tor network to communicate anonymously via the Internet and gain access to online media that are not accessible using standard Internet technology. This sphere of communication can be described as the hidden web. In part because this phenomenon is very recent, the subject has scarcely been studied in the social sciences. It is therefore the purpose of this paper to answer four fundamental questions: What is the hidden web? What charact...

  3. Platform-based production development

    DEFF Research Database (Denmark)

    Bossen, Jacob; Brunoe, Thomas Ditlev; Nielsen, Kjeld

    2015-01-01

    Platforms as a means for applying modular thinking in product development is relatively well studied, but platforms in the production system has until now not been given much attention. With the emerging concept of platform-based co-development the importance of production platforms is though...... indisputable. This paper presents state-of-the-art literature on platform research related to production platforms and investigates gaps in the literature. The paper concludes on findings by proposing future research directions....

  4. USA Hire Testing Platform

    Data.gov (United States)

    Office of Personnel Management — The USA Hire Testing Platform delivers tests used in hiring for positions in the Federal Government. To safeguard the integrity of the hiring processes and ensure...

  5. MULTIFUNCTIONAL PLATFORMS AND

    African Journals Online (AJOL)

    Solar service centres and multifunctional platforms are innovative concepts for providing energy services in ... same time generate income. obeng ..... communities the driving force behind the ... operator(s) had to contact repairers outside their.

  6. The Common HOL Platform

    Directory of Open Access Journals (Sweden)

    Mark Adams

    2015-07-01

    Full Text Available The Common HOL project aims to facilitate porting source code and proofs between members of the HOL family of theorem provers. At the heart of the project is the Common HOL Platform, which defines a standard HOL theory and API that aims to be compatible with all HOL systems. So far, HOL Light and hol90 have been adapted for conformance, and HOL Zero was originally developed to conform. In this paper we provide motivation for a platform, give an overview of the Common HOL Platform's theory and API components, and show how to adapt legacy systems. We also report on the platform's successful application in the hand-translation of a few thousand lines of source code from HOL Light to HOL Zero.

  7. The Creative Platform

    DEFF Research Database (Denmark)

    Byrge, Christian; Hansen, Søren

    whether you consider thirdgrade teaching, human-resource development, or radical new thinking in product development in a company. The Creative Platform was developed at Aalborg University through a series of research-and-development activities in collaboration with educational institutions and private......This book is about introducing more creativity into general educational courses and cross-disciplinary activities. It is directed toward teachers at all levels in the educational system, but the Creative Platform is a general model, and thus the creative process will fundamentally be the same...... companies. It is a project in which the goal is to make a hands-on approach to a knowledge perspective on enhancing creativity. The underlying ambition of the Creative Platform is to make it easier to promote creativity. At www.uka.aau.dk/The+Creative+Platform, you can find extra materials and instructions...

  8. Disease surveillance using a hidden Markov model

    Directory of Open Access Journals (Sweden)

    Wright Graeme

    2009-08-01

    Full Text Available Abstract Background Routine surveillance of disease notification data can enable the early detection of localised disease outbreaks. Although hidden Markov models (HMMs have been recognised as an appropriate method to model disease surveillance data, they have been rarely applied in public health practice. We aimed to develop and evaluate a simple flexible HMM for disease surveillance which is suitable for use with sparse small area count data and requires little baseline data. Methods A Bayesian HMM was designed to monitor routinely collected notifiable disease data that are aggregated by residential postcode. Semi-synthetic data were used to evaluate the algorithm and compare outbreak detection performance with the established Early Aberration Reporting System (EARS algorithms and a negative binomial cusum. Results Algorithm performance varied according to the desired false alarm rate for surveillance. At false alarm rates around 0.05, the cusum-based algorithms provided the best overall outbreak detection performance, having similar sensitivity to the HMMs and a shorter average time to detection. At false alarm rates around 0.01, the HMM algorithms provided the best overall outbreak detection performance, having higher sensitivity than the cusum-based Methods and a generally shorter time to detection for larger outbreaks. Overall, the 14-day HMM had a significantly greater area under the receiver operator characteristic curve than the EARS C3 and 7-day negative binomial cusum algorithms. Conclusion Our findings suggest that the HMM provides an effective method for the surveillance of sparse small area notifiable disease data at low false alarm rates. Further investigations are required to evaluation algorithm performance across other diseases and surveillance contexts.

  9. 'Hidden messages' emerging from Afrocentric management perspectives

    Directory of Open Access Journals (Sweden)

    H. Van den Heuvel

    2008-12-01

    Full Text Available Purpose: This paper aims to examine how 'African management' discourse has emerged in South Africa. Altogether, it has stimulated debates - sometimes in controversial ways - on 'taboo issues', e.g. relating to 'cultural diversity' and 'ethnicity'. The stimulation of such debates within organisations is probably a more valuable contribution than a static, essentialised 'African identity' that it proclaims. Design/Methodology/Approach: The paper draws on a qualitative research project conducted in South Africa in 2003-2004. Its relevance lies in gaining in-depth insights into ('non-western' local management discourse. It seeks to contribute to the body of knowledge on political and cultural contexts in which South African organizations operate, and how they impact on local management perspectives, and vice versa. Findings: The research findings make clear how and under what circumstances 'African management' discourse has come about in South Africa, and how it could be interpreted. Implications: 'African management' advocates allegedly attempt to revise dominant management thinking and promote 'humane-ness' and participatory decision-making in South African organisations, in search of a contextualised management approach. Amongst others, it has produced new meanings of 'Africanness' and has opened up space for 'hidden messages', resentments and aspirations to become openly articulated. This throws another light on phenomena such as cultural diversity and ethnicity that usually tend to be 'neutralised'. This may turn out to be far healthier for blooming organisational cultures in South Africa than relentlessly hammering on prescribed 'corporate values'. Originality/Value: This paper informs the reader in detail about the emergence and evolvement of 'African management' discourse in South Africa. It is a unique attempt to develop an interpretative viewpoint on this intriguing phenomenon that offers a potentially valuable contribution in reading

  10. Foundational Forces & Hidden Variables in Technology Commercialization

    Science.gov (United States)

    Barnett, Brandon

    2011-03-01

    The science of physics seems vastly different from the process of technology commercialization. Physics strives to understand our world through the experimental deduction of immutable laws and dependent variables and the resulting macro-scale phenomenon. In comparison, the~goal of business is to make a profit by addressing the needs, preferences, and whims of individuals in a market. It may seem that this environment is too dynamic to identify all the hidden variables and deduct the foundational forces that impact a business's ability to commercialize innovative technologies. One example of a business ``force'' is found in the semiconductor industry. In 1965, Intel co-founder Gordon Moore predicted that the number of transistors incorporated in a chip will approximately double every 24 months. Known as Moore's Law, this prediction has become the guiding principle for the semiconductor industry for the last 40 years. Of course, Moore's Law is not really a law of nature; rather it is the result of efforts by Intel and the entire semiconductor industry. A closer examination suggests that there are foundational principles of business that underlie the macro-scale phenomenon of Moore's Law. Principles of profitability, incentive, and strategic alignment have resulted in a coordinated influx of resources that has driven technologies to market, increasing the profitability of the semiconductor industry and optimizing the fitness of its participants. New innovations in technology are subject to these same principles. So, in addition to traditional market forces, these often unrecognized forces and variables create challenges for new technology commercialization. In this talk, I will draw from ethnographic research, complex adaptive theory, and industry data to suggest a framework with which to think about new technology commercialization. Intel's bio-silicon initiative provides a case study.

  11. National Community Solar Platform

    Energy Technology Data Exchange (ETDEWEB)

    Rupert, Bart [Clean Energy Collective, Louisville, CO (United States)

    2016-06-30

    This project was created to provide a National Community Solar Platform (NCSP) portal known as Community Solar Hub, that is available to any entity or individual who wants to develop community solar. This has been done by providing a comprehensive portal to make CEC’s solutions, and other proven community solar solutions, externally available for everyone to access – making the process easy through proven platforms to protect subscribers, developers and utilities. The successful completion of this project provides these tools via a web platform and integration APIs, a wide spectrum of community solar projects included in the platform, multiple groups of customers (utilities, EPCs, and advocates) using the platform to develop community solar, and open access to anyone interested in community solar. CEC’s Incubator project includes web-based informational resources, integrated systems for project information and billing systems, and engagement with customers and users by community solar experts. The combined effort externalizes much of Clean Energy Collective’s industry-leading expertise, allowing third parties to develop community solar without duplicating expensive start-up efforts. The availability of this platform creates community solar projects that are cheaper to build and cheaper to participate in, furthering the goals of DOE’s SunShot Initiative. Final SF 425 Final SF 428 Final DOE F 2050.11 Final Report Narrative

  12. The Platformization of the Web: Making Web Data Platform Ready

    NARCIS (Netherlands)

    A. Helmond

    2015-01-01

    In this article, I inquire into Facebook’s development as a platform by situating it within the transformation of social network sites into social media platforms. I explore this shift with a historical perspective on, what I refer to as, platformization, or the rise of the platform as the dominant

  13. Platform Performance and Challenges - using Platforms in Lego Company

    DEFF Research Database (Denmark)

    Munk, Lone; Mortensen, Niels Henrik

    2009-01-01

    by the product defining users (product developers) and platform erosion. When the platforms are not used it is due to: unsuitable calculation models, lack of goals, rewards or benefits from management, unattractive tradeoffs and difficulties in understanding the platform. This indicates that platform design...... needs focus on the incentive of using the platform. This problem lacks attention in literature, as well as industry, where assessment criteria do not cover this aspect. Therefore, we recommend including user incentive in platform assessment criteria to these challenges. Concrete solution elements...... ensuring user incentive in platforms is an object for future research...

  14. Hidden Gauge Structure of Supersymmetric Free Differential Algebras

    CERN Document Server

    Andrianopoli, L; Ravera, L

    2016-01-01

    The aim of this paper is to clarify the role of the nilpotent fermionic generator Q' introduced in Ref. [3] and appearing in the hidden supergroup underlying the free differential algebra (FDA) of D=11 supergravity. We give a physical explanation of its role by looking at the gauge properties of the theory. We find that its presence is necessary, in order that the extra 1-forms of the hidden supergroup give rise to the correct gauge transformations of the p-forms of the FDA. This interpretation is actually valid for any supergravity containing antisymmetric tensor fields, and any supersymmetric FDA can always be traded for a hidden Lie superalgebra containing extra fermionic nilpotent generators. As an interesting example we construct the hidden superalgebra associated with the FDA of N=2, D=7 supergravity. In this case we are able to parametrize the mutually non local 2- and 3-form B^(2) and B^(3) in terms of hidden 1-forms and find that supersymmetry and gauge invariance require in general the presence of t...

  15. On the Complexity of Trial and Error

    CERN Document Server

    Bei, Xiaohui; Zhang, Shengyu

    2012-01-01

    Motivated by certain applications from physics, biochemistry, economics, and computer science, in which the objects under investigation are not accessible because of various limitations, we propose a trial-and-error model to examine algorithmic issues in such situations. Given a search problem with a hidden input, we are asked to find a valid solution, to find which we can propose candidate solutions (trials), and use observed violations (errors), to prepare future proposals. In accordance with our motivating applications, we consider the fairly broad class of constraint satisfaction problems, and assume that errors are signaled by a verification oracle in the format of the index of a violated constraint (with the content of the constraint still hidden). Our discoveries are summarized as follows. On one hand, despite the seemingly very little information provided by the verification oracle, efficient algorithms do exist for a number of important problems. For the Nash, Core, Stable Matching, and SAT problems,...

  16. Evidence Feed Forward Hidden Markov Model: A New Type of Hidden Markov Model

    CERN Document Server

    DelRose, Michael; Frederick, Philip; 10.5121/ijaia.2011.2101

    2011-01-01

    The ability to predict the intentions of people based solely on their visual actions is a skill only performed by humans and animals. The intelligence of current computer algorithms has not reached this level of complexity, but there are several research efforts that are working towards it. With the number of classification algorithms available, it is hard to determine which algorithm works best for a particular situation. In classification of visual human intent data, Hidden Markov Models (HMM), and their variants, are leading candidates. The inability of HMMs to provide a probability in the observation to observation linkages is a big downfall in this classification technique. If a person is visually identifying an action of another person, they monitor patterns in the observations. By estimating the next observation, people have the ability to summarize the actions, and thus determine, with pretty good accuracy, the intention of the person performing the action. These visual cues and linkages are important...

  17. Hidden Statistics Approach to Quantum Simulations

    Science.gov (United States)

    Zak, Michail

    2010-01-01

    Recent advances in quantum information theory have inspired an explosion of interest in new quantum algorithms for solving hard computational (quantum and non-quantum) problems. The basic principle of quantum computation is that the quantum properties can be used to represent structure data, and that quantum mechanisms can be devised and built to perform operations with this data. Three basic non-classical properties of quantum mechanics superposition, entanglement, and direct-product decomposability were main reasons for optimism about capabilities of quantum computers that promised simultaneous processing of large massifs of highly correlated data. Unfortunately, these advantages of quantum mechanics came with a high price. One major problem is keeping the components of the computer in a coherent state, as the slightest interaction with the external world would cause the system to decohere. That is why the hardware implementation of a quantum computer is still unsolved. The basic idea of this work is to create a new kind of dynamical system that would preserve the main three properties of quantum physics superposition, entanglement, and direct-product decomposability while allowing one to measure its state variables using classical methods. In other words, such a system would reinforce the advantages and minimize limitations of both quantum and classical aspects. Based upon a concept of hidden statistics, a new kind of dynamical system for simulation of Schroedinger equation is proposed. The system represents a modified Madelung version of Schroedinger equation. It preserves superposition, entanglement, and direct-product decomposability while allowing one to measure its state variables using classical methods. Such an optimal combination of characteristics is a perfect match for simulating quantum systems. The model includes a transitional component of quantum potential (that has been overlooked in previous treatment of the Madelung equation). The role of the

  18. Transactional Network Platform: Applications

    Energy Technology Data Exchange (ETDEWEB)

    Katipamula, Srinivas; Lutes, Robert G.; Ngo, Hung; Underhill, Ronald M.

    2013-10-31

    In FY13, Pacific Northwest National Laboratory (PNNL) with funding from the Department of Energy’s (DOE’s) Building Technologies Office (BTO) designed, prototyped and tested a transactional network platform to support energy, operational and financial transactions between any networked entities (equipment, organizations, buildings, grid, etc.). Initially, in FY13, the concept demonstrated transactions between packaged rooftop air conditioners and heat pump units (RTUs) and the electric grid using applications or "agents" that reside on the platform, on the equipment, on a local building controller or in the Cloud. The transactional network project is a multi-lab effort with Oakridge National Laboratory (ORNL) and Lawrence Berkeley National Laboratory (LBNL) also contributing to the effort. PNNL coordinated the project and also was responsible for the development of the transactional network (TN) platform and three different applications associated with RTUs. This document describes two applications or "agents" in details, and also summarizes the platform. The TN platform details are described in another companion document.

  19. Hidden beauty baryon states in the local hidden gauge approach with heavy quark spin symmetry

    Energy Technology Data Exchange (ETDEWEB)

    Xiao, C.W.; Oset, E. [Centro Mixto Universidad de Valencia-CSIC, Institutos de Investigacion de Paterna, Departamento de Fisica Teorica and IFIC, Valencia (Spain)

    2013-11-15

    Using a coupled-channel unitary approach, combining the heavy quark spin symmetry and the dynamics of the local hidden gauge, we investigate the meson-baryon interaction with hidden beauty and obtain several new states of N around 11 GeV. We consider the basis of states {eta}{sub b} N, {Upsilon};N, B {Lambda}{sub b}, B {Sigma}{sub b}, B{sup *}{Lambda}{sub b}, B{sup *}{Sigma}{sub b}, B{sup *}{Sigma}{sub b}{sup *} and find four basic bound states which correspond to B {Sigma}{sub b}, B {Sigma}{sub b}{sup *}, B{sup *}{Sigma}{sub b} and B{sup *}{Sigma}{sub b}{sup *}, decaying mostly into {eta}{sub b} N and {Upsilon}N and with a binding energy about 50-130 MeV with respect to the thresholds of the corresponding channel. All of them have isospin I = 1/2, and we find no bound states or resonances in I = 3/2. The B {Sigma}{sub b} state appears in J = 1/2, the B {Sigma}{sub b}{sup *} in J = 3/2, the B{sup *}{Sigma}{sub b} appears nearly degenerate in J = 1/2, 3/2 and the B{sup *}{Sigma}{sub b}{sup *} appears nearly degenerate in J = 1/2, 3/2, 5/2. These states have a width from 2-110 MeV, with conservative estimates of uncertainties, except for the one in J = 5/2 which has zero width since it cannot decay into any of the states of the basis chosen. We make generous estimates of the uncertainties and find that within very large margins these states appear bound. (orig.)

  20. Evidence Feed Forward Hidden Markov Model: A New Type Of Hidden Markov Model

    Directory of Open Access Journals (Sweden)

    Michael Del Rose

    2011-01-01

    Full Text Available The ability to predict the intentions of people based solely on their visual actions is a skill only performed by humans and animals. The intelligence of current computer algorithms has not reached this level of complexity, but there are several research efforts that are working towards it. With the number of classification algorithms available, it is hard to determine which algorithm works best for a particular situation. In classification of visual human intent data, Hidden Markov Models (HMM, and their variants, are leading candidates. The inability of HMMs to provide a probability in the observation to observation linkages is a big downfall in this classification technique. If a person is visually identifying an action of another person, they monitor patterns in the observations. By estimating the next observation, people have the ability to summarize the actions, and thus determine, with pretty good accuracy, the intention of the person performing the action. These visual cues and linkages are important in creating intelligent algorithms for determining human actions based on visual observations. The Evidence Feed Forward Hidden Markov Model is a newly developed algorithm which provides observation to observation linkages. The following research addresses the theory behind Evidence Feed Forward HMMs, provides mathematical proofs of their learning of these parameters to optimize the likelihood of observations with a Evidence Feed Forwards HMM, which is important in all computational intelligence algorithm, and gives comparative examples with standard HMMs in classification of both visual action data and measurement data; thus providing a strong base for Evidence Feed Forward HMMs in classification of many types of problems.

  1. Recent Progress in Search for Hidden/Dark Photon

    CERN Document Server

    Deliyergiyev, M A

    2015-01-01

    We will try to communicate the many difficulties that we encounter when attempting to pinpoint a common origin for the several observed anomalies, or assessing their tension with existing exclusion limits. These include systematics affecting the operation of the detectors, our knowledge of their response, astrophysical uncertainties, and the broad range of particle couplings that can mediate the interaction with a detector target. The interesting astrophysical evidence that motivates a search for dark-photon and focuses our attention on a Hidden Valleys model with a GeV-scale dark sector that produces the exciting signatures, which may include the possible constituent of dark matter, the possible existence of extra gauge groups. Results from the recent underground experiments are also considered. Many models of new physics beyond the Standard Model contain a 'light' hidden sector (dark sector) with a colorful spectrum of new particles. Recently, it has been shown that the hidden sector can give rise to unique...

  2. Applications of hidden symmetries to black hole physics

    Energy Technology Data Exchange (ETDEWEB)

    Frolov, Valeri, E-mail: vfrolov@ualberta.ca [Institute of Theoretical Physics, Department of Physics University of Alberta, Edmonton, Alberta, T6G 2G7 (Canada)

    2011-02-01

    This work is a brief review of applications of hidden symmetries to black hole physics. Symmetry is one of the most important concepts of the science. In physics and mathematics the symmetry allows one to simplify a problem, and often to make it solvable. According to the Noether theorem symmetries are responsible for conservation laws. Besides evident (explicit) spacetime symmetries, responsible for conservation of energy, momentum, and angular momentum of a system, there also exist what is called hidden symmetries, which are connected with higher order in momentum integrals of motion. A remarkable fact is that black holes in four and higher dimensions always possess a set ('tower') of explicit and hidden symmetries which make the equations of motion of particles and light completely integrable. The paper gives a general review of the recently obtained results. The main focus is on understanding why at all black holes have something (symmetry) to hide.

  3. The hidden-charm pentaquark and tetraquark states

    CERN Document Server

    Chen, Hua-Xing; Liu, Xiang; Zhu, Shi-Lin

    2016-01-01

    In the past decade many charmonium-like states were observed experimentally. Especially those charged charmonium-like $Z_c$ states and bottomonium-like $Z_b$ states can not be accommodated within the naive quark model. These charged $Z_c$ states are good candidates of either the hidden-charm tetraquark states or molecules composed of a pair of charmed mesons. Recently, the LHCb Collaboration discovered two hidden-charm pentaquark states, which are also beyond the quark model. In this work, we review the current experimental progress and investigate various theoretical interpretations of these candidates of the multiquark states. We list the puzzles and theoretical challenges of these models when confronted with the experimental data. We also discuss possible future measurements which may distinguish the theoretical schemes on the underlying structures of the hidden-charm multiquark states.

  4. Ontology-based Knowledge Extraction from Hidden Web

    Institute of Scientific and Technical Information of China (English)

    SONG Hui; MA Fan-yuan; LIU Xiao-qiang

    2004-01-01

    Hidden Web provides great amount of domain-specific data for constructing knowledge services. Most previous knowledge extraction researches ignore the valuable data hidden in Web database, and related works do not refer how to make extracted information available for knowledge system. This paper describes a novel approach to build a domain-specific knowledge service with the data retrieved from Hidden Web. Ontology serves to model the domain knowledge. Queries forms of different Web sites are translated into machine-understandable format, defined knowledge concepts, so that they can be accessed automatically. Also knowledge data are extracted from Web pages and organized in ontology format knowledge. The experiment proves the algorithm achieves high accuracy and the system facilitates constructing knowledge services greatly.

  5. Applications of hidden symmetries to black hole physics

    CERN Document Server

    Frolov, Valeri

    2010-01-01

    This work is a brief review of applications of hidden symmetries to black hole physics. Symmetry is one of the most important concepts of the science. In physics and mathematics the symmetry allows one to simplify a problem, and often to make it solvable. According to the Noether theorem symmetries are responsible for conservation laws. Besides evident (explicit) spacetime symmetries, responsible for conservation of energy, momentum, and angular momentum of a system, there also exist what is called hidden symmetries, which are connected with higher order in momentum integrals of motion. A remarkable fact is that black holes in four and higher dimensions always possess a set (`tower') of explicit and hidden symmetries which make the equations of motion of particles and light completely integrable. The paper gives a general review of the recently obtained results. The main focus is on understanding why at all black holes have something (symmetry) to hide.

  6. Using the hidden curriculum to teach professionalism in nursing students.

    Science.gov (United States)

    Karimi, Zohreh; Ashktorab, Tahereh; Mohammadi, Easa; Abedi, Heidar Ali

    2014-03-01

    Professionalism in nursing is critical for creating credibility and a positive image. This study was carried out to explain the use of hidden curriculum in teaching professionalism in nursing students. This qualitative study was conducted through purposeful sampling strategy by the participation of 32 nursing students. The data were collected by using semi-structured interviews, and this process was continued until achieving data saturation and themes' emergence. Content analysis method was used for data analysis. DATA ANALYSIS REVEALED THREE MAIN THEMES: Development of understanding the professionalism elements, Variety of influenceability strategies, and Influenceability to various resources. Each theme consisted of some subthemes. The nursing students learnt the professionalism elements by different methods from different resources through the hidden curriculum. Therefore, exploration of the currently administered hidden curricula is suggested.

  7. Graph processing platforms at scale: practices and experiences

    Energy Technology Data Exchange (ETDEWEB)

    Lim, Seung-Hwan [ORNL; Lee, Sangkeun (Matt) [ORNL; Brown, Tyler C [ORNL; Sukumar, Sreenivas R [ORNL; Ganesh, Gautam [ORNL

    2015-01-01

    Graph analysis unveils hidden associations of data in many phenomena and artifacts, such as road network, social networks, genomic information, and scientific collaboration. Unfortunately, a wide diversity in the characteristics of graphs and graph operations make it challenging to find a right combination of tools and implementation of algorithms to discover desired knowledge from the target data set. This study presents an extensive empirical study of three representative graph processing platforms: Pegasus, GraphX, and Urika. Each system represents a combination of options in data model, processing paradigm, and infrastructure. We benchmarked each platform using three popular graph operations, degree distribution, connected components, and PageRank over a variety of real-world graphs. Our experiments show that each graph processing platform shows different strength, depending the type of graph operations. While Urika performs the best in non-iterative operations like degree distribution, GraphX outputforms iterative operations like connected components and PageRank. In addition, we discuss challenges to optimize the performance of each platform over large scale real world graphs.

  8. Identification of platform levels

    DEFF Research Database (Denmark)

    Mortensen, Niels Henrik

    2005-01-01

    reduction, ability to launch a wider product portfolio without increasing resources and reduction of complexity within the whole company. To support the multiple product development process, platform based product development has in many companies such as Philips, VW, Ford etc. proven to be a very effective...... because the nature of developing platforms and applications are very different. In single product development reuse is often determined by individual designers, in multiple product development reuse is to a large degree a management issue. It is difficult for a company to switch from single to multiple...... development will be examined. Based on the identification of the above characteristics five platform levels are described. The research presented in this paper is a result of MSc, Ph.D projects at the Technical University of Denmark and consultancy projects within the organisation of Institute of Product...

  9. Universal visualization platform

    Science.gov (United States)

    Gee, Alexander G.; Li, Hongli; Yu, Min; Smrtic, Mary Beth; Cvek, Urska; Goodell, Howie; Gupta, Vivek; Lawrence, Christine; Zhou, Jainping; Chiang, Chih-Hung; Grinstein, Georges G.

    2005-03-01

    Although there are a number of visualization systems to choose from when analyzing data, only a few of these allow for the integration of other visualization and analysis techniques. There are even fewer visualization toolkits and frameworks from which one can develop ones own visualization applications. Even within the research community, scientists either use what they can from the available tools or start from scratch to define a program in which they are able to develop new or modified visualization techniques and analysis algorithms. Presented here is a new general-purpose platform for constructing numerous visualization and analysis applications. The focus of this system is the design and experimentation of new techniques, and where the sharing of and integration with other tools becomes second nature. Moreover, this platform supports multiple large data sets, and the recording and visualizing of user sessions. Here we introduce the Universal Visualization Platform (UVP) as a modern data visualization and analysis system.

  10. Geostationary multipurpose platforms

    Science.gov (United States)

    Bekey, I.; Bowman, R. M.

    1981-01-01

    In addition to the advantages generally associated with orbital platforms, such as improved reliability, economies of scale, simple connectivity of elements, reduced tracking demands and the restraint of orbital object population growth, geostationary platforms yield: (1) continuous access by fixed ground antennas for communications services; (2) continuous monitoring of phenomena over chosen regions of the earth's surface; (3) a preferred location for many solar-terrestrial physics experiments. The geostationary platform also offers a low-risk and economical solution to the impending saturation of the orbital arc/frequency spectrum, maximizing the capacity of individual slots and increasing the utility of the entire arc. It also allows the use of many small, simple and inexpensive earth stations through complexity inversion and high power per beam. Block diagram and operational flowcharts are provided.

  11. Platforms for antibiotic discovery.

    Science.gov (United States)

    Lewis, Kim

    2013-05-01

    The spread of resistant bacteria, leading to untreatable infections, is a major public health threat but the pace of antibiotic discovery to combat these pathogens has slowed down. Most antibiotics were originally isolated by screening soil-derived actinomycetes during the golden era of antibiotic discovery in the 1940s to 1960s. However, diminishing returns from this discovery platform led to its collapse, and efforts to create a new platform based on target-focused screening of large libraries of synthetic compounds failed, in part owing to the lack of penetration of such compounds through the bacterial envelope. This article considers strategies to re-establish viable platforms for antibiotic discovery. These include investigating untapped natural product sources such as uncultured bacteria, establishing rules of compound penetration to enable the development of synthetic antibiotics, developing species-specific antibiotics and identifying prodrugs that have the potential to eradicate dormant persisters, which are often responsible for hard-to-treat infections.

  12. Platform switch and dental implants: A meta-analysis.

    Science.gov (United States)

    Chrcanovic, Bruno Ramos; Albrektsson, Tomas; Wennerberg, Ann

    2015-06-01

    To test the null hypothesis of no difference in the implant failure rates, marginal bone loss (MBL) and postoperative infection in patients who received platform-switched implants or platform-matched implants, against the alternative hypothesis of a difference. Main search terms used in combination: dental implant, oral implant, platform switch, switched platform, platform mismatch, and dental implant-abutment design. An electronic search without time or language restrictions was undertaken in December/2014 in PubMed/Medline, Web of Science, Cochrane Oral Health Group Trials Register plus hand-searching. Eligibility criteria included clinical human studies, either randomized or not. Twenty-eight publications were included, with a total of 1216 platform-switched implants (16 failures; 1.32%) and 1157 platform-matched implants (13 failures; 1.12%). There was less MBL loss at implants with platform-switching than at implants with platform-matching (mean difference -0.29, 95% CI -0.38 to -0.19; Pimplant platform and the abutment (P=0.001). Due to lack of satisfactory information, meta-analyses for the outcomes 'implant failure' and 'postoperative infection' were not performed. The results of the present review should be interpreted with caution due to the presence of uncontrolled confounding factors in the included studies, most of them with short follow-up periods. The question whether platform-matched implants are more at risk for failure and loose more marginal bone than platform-switched implants has received increasing attention in the last years. As the philosophies of treatment alter over time, a periodic review of the different concepts is necessary to refine techniques and eliminate unnecessary procedures, forming a basis for optimum treatment. Copyright © 2014 Elsevier Ltd. All rights reserved.

  13. QCD sum rule study of hidden-charm pentaquarks

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Hua-Xing; Cui, Er-Liang [Beihang University, School of Physics and Beijing Key Laboratory of Advanced Nuclear Materials and Physics, Beijing (China); Chen, Wei; Steele, T.G. [University of Saskatchewan, Department of Physics and Engineering Physics, Saskatoon, Saskatchewan (Canada); Liu, Xiang [Lanzhou University, School of Physical Science and Technology, Lanzhou (China); Lanzhou University and Institute of Modern Physics of CAS, Research Center for Hadron and CSR Physics, Lanzhou (China); Zhu, Shi-Lin [Peking University, School of Physics and State Key Laboratory of Nuclear Physics and Technology, Beijing (China); Collaborative Innovation Center of Quantum Matter, Beijing (China); Peking University, Center of High Energy Physics, Beijing (China)

    2016-10-15

    We study the mass spectra of hidden-charm pentaquarks having spin J = (1)/(2)/(3)/(2)/(5)/(2) and quark contents uudc anti c. We systematically construct all the relevant local hidden-charm pentaquark currents, and we select some of them to perform QCD sum rule analyses. We find that the P{sub c}(4380) and P{sub c}(4450) can be identified as hidden-charm pentaquark states composed of an anti-charmed meson and a charmed baryon. Besides them, we also find (a) the lowest-lying hidden-charm pentaquark state of J{sup P} = 1/2{sup -} has the mass 4.33{sup +0.17}{sub -0.13} GeV, while the one of J{sup P} = 1/2{sup +} is significantly higher, that is, around 4.7-4.9 GeV; (b) the lowest-lying hidden-charm pentaquark state of J{sup P} = 3/2{sup -} has the mass 4.37{sup +0.18}{sub -0.13} GeV, consistent with the P{sub c}(4380) of J{sup P} = 3/2{sup -}, while the one of J{sup P} = 3/2{sup +} is also significantly higher, that is, above 4.6 GeV; (c) the hidden-charm pentaquark state of J{sup P} = 5/2{sup -} has a mass around 4.5-4.6 GeV, slightly larger than the P{sub c}(4450) of J{sup P} = 5/2{sup +}. (orig.)

  14. Detect and exploit hidden structure in fatty acid signature data

    Science.gov (United States)

    Budge, Suzanne; Bromaghin, Jeffrey; Thiemann, Gregory

    2017-01-01

    Estimates of predator diet composition are essential to our understanding of their ecology. Although several methods of estimating diet are practiced, methods based on biomarkers have become increasingly common. Quantitative fatty acid signature analysis (QFASA) is a popular method that continues to be refined and extended. Quantitative fatty acid signature analysis is based on differences in the signatures of prey types, often species, which are recognized and designated by investigators. Similarly, predator signatures may be structured by known factors such as sex or age class, and the season or region of sample collection. The recognized structure in signature data inherently influences QFASA results in important and typically beneficial ways. However, predator and prey signatures may contain additional, hidden structure that investigators either choose not to incorporate into an analysis or of which they are unaware, being caused by unknown ecological mechanisms. Hidden structure also influences QFASA results, most often negatively. We developed a new method to explore signature data for hidden structure, called divisive magnetic clustering (DIMAC). Our DIMAC approach is based on the same distance measure used in diet estimation, closely linking methods of data exploration and parameter estimation, and it does not require data transformation or distributional assumptions, as do many multivariate ordination methods in common use. We investigated the potential benefits of the DIMAC method to detect and subsequently exploit hidden structure in signature data using two prey signature libraries with quite different characteristics. We found that the existence of hidden structure in prey signatures can increase the confusion between prey types and thereby reduce the accuracy and precision of QFASA diet estimates. Conversely, the detection and exploitation of hidden structure represent a potential opportunity to improve predator diet estimates and may lead to new

  15. Performance based analysis of hidden beams in reinforced concrete structures

    Directory of Open Access Journals (Sweden)

    Helou Samir H.

    2014-01-01

    Full Text Available Local and perhaps regional vernacular reinforced concrete building construction leans heavily against designing slabs with imbedded hidden beams for flooring systems in most structures including major edifices. The practice is distinctive in both framed and in shear wall structures. Hidden beams are favoured structural elements due to their many inherent features that characterize them; they save on floor height clearance; they also save on formwork, labour and material cost. Moreover, hidden beams form an acceptable aesthetic appearance that does not hinder efficient interior space partitioning. Such beams have the added advantage of clearing the way for horizontal electromechanical ductwork. However, seismic considerations, in all likelihood, are seldom seriously addressed. The mentioned structural system of shallow beams is adopted in ribbed slabs, waffle slabs and at times with solid slabs. Ribbed slabs and waffle slabs are more prone to hidden beam inclusion due to the added effective height of the concrete section. Due to the presence of a relatively high reinforcement ratio at the joints the sections at such location tend to become less ductile with unreliable contribution to spandrel force resistance. In the following study the structural influence of hidden beams within slabs is investigated. With the primary focus on a performance based analysis of such elements within a structure. This is investigated with due attention to shear wall contribution to the overall behaviour of such structures. Numerical results point in the direction that the function of hidden beams is not as adequate as desired. Therefore it is strongly believed that they are generally superfluous and maybe eliminated altogether. Conversely, shallow beams seem to render the overall seismic capacity of the structure unreliable. Since such an argument is rarely manifested within the linear analysis domain; a pushover analysis exercise is thus mandatory for behaviour

  16. Windows Azure Platform

    CERN Document Server

    Redkar, Tejaswi

    2011-01-01

    The Windows Azure Platform has rapidly established itself as one of the most sophisticated cloud computing platforms available. With Microsoft working to continually update their product and keep it at the cutting edge, the future looks bright - if you have the skills to harness it. In particular, new features such as remote desktop access, dynamic content caching and secure content delivery using SSL make the latest version of Azure a more powerful solution than ever before. It's widely agreed that cloud computing has produced a paradigm shift in traditional architectural concepts by providin

  17. Windows Azure Platform

    CERN Document Server

    Redkar, Tejaswi

    2010-01-01

    The Azure Services Platform is a brand-new cloud-computing technology from Microsoft. It is composed of four core components-Windows Azure, .NET Services, SQL Services, and Live Services-each with a unique role in the functioning of your cloud service. It is the goal of this book to show you how to use these components, both separately and together, to build flawless cloud services. At its heart Windows Azure Platform is a down-to-earth, code-centric book. This book aims to show you precisely how the components are employed and to demonstrate the techniques and best practices you need to know

  18. Wireless sensor platform

    Energy Technology Data Exchange (ETDEWEB)

    Joshi, Pooran C.; Killough, Stephen M.; Kuruganti, Phani Teja

    2017-08-08

    A wireless sensor platform and methods of manufacture are provided. The platform involves providing a plurality of wireless sensors, where each of the sensors is fabricated on flexible substrates using printing techniques and low temperature curing. Each of the sensors can include planar sensor elements and planar antennas defined using the printing and curing. Further, each of the sensors can include a communications system configured to encode the data from the sensors into a spread spectrum code sequence that is transmitted to a central computer(s) for use in monitoring an area associated with the sensors.

  19. Mobile4D platform

    CSIR Research Space (South Africa)

    Botha, Adèle

    2010-05-01

    Full Text Available . It is a communication platform that has architecture for creating, deploying and managing services and applications by integrating voice, video and data across a range of IP and telecom communication networks. In 2007, Red Hat made a firm commitment... based on the Mobicents muni ations Platform brand. 2.1.5  Telco specific User‐Generated Services   A variety of communication network operators have started initiatives to address User- Generated Services for the Telecom domain. Some...

  20. Reheating the Standard Model from a hidden sector

    Science.gov (United States)

    Tenkanen, Tommi; Vaskonen, Ville

    2016-10-01

    We consider a scenario where the inflaton decays to a hidden sector thermally decoupled from the visible Standard Model sector. A tiny portal coupling between the hidden and the visible sectors later heats the visible sector so that the Standard Model degrees of freedom come to dominate the energy density of the Universe before big bang nucleosynthesis. We find that this scenario is viable, although obtaining the correct dark matter abundance and retaining successful big bang nucleosynthesis is not obvious. We also show that the isocurvature perturbations constituted by a primordial Higgs condensate are not problematic for the viability of the scenario.

  1. On Noncontextual, Non-Kolmogorovian Hidden Variable Theories

    Science.gov (United States)

    Feintzeig, Benjamin H.; Fletcher, Samuel C.

    2017-01-01

    One implication of Bell's theorem is that there cannot in general be hidden variable models for quantum mechanics that both are noncontextual and retain the structure of a classical probability space. Thus, some hidden variable programs aim to retain noncontextuality at the cost of using a generalization of the Kolmogorov probability axioms. We generalize a theorem of Feintzeig (Br J Philos Sci 66(4): 905-927, 2015) to show that such programs are committed to the existence of a finite null cover for some quantum mechanical experiments, i.e., a finite collection of probability zero events whose disjunction exhausts the space of experimental possibilities.

  2. Backward causation, hidden variables and the meaning of completeness

    Indian Academy of Sciences (India)

    Huw Price

    2001-02-01

    Bell’s theorem requires the assumption that hidden variables are independent of future measurement settings. This independence assumption rests on surprisingly shaky ground. In particular, it is puzzlingly time-asymmetric. The paper begins with a summary of the case for considering hidden variable models which, in abandoning this independence assumption, allow a degree of ‘backward causation’. The remainder of the paper clarifies the physical significance of such models, in relation to the issue as to whether quantum mechanics provides a complete description of physical reality.

  3. Dynamically Generated Open and Hidden Charm Meson Systems

    CERN Document Server

    Gamermann, D; Strottman, D D; Vacas, M J V

    2006-01-01

    The lowest order chiral Lagrangian successfully applied to study the interaction of the SU(3) octet of pseudo-scalar mesons is generalized to include all mesons from the SU(4) 15-plet of pseudo-scalar mesons. Exchanges of heavy vector mesons, which are indirectly taken into account via this approach, are suppressed. Unitarization in coupled channels leads to dynamical generation of resonances in the open and hidden charm sectors. In particular, for reasonable values of the input, a new narrow scalar resonance in the hidden charm sector appears with a mass of 3.7 GeV.

  4. Reheating the Standard Model from a Hidden Sector

    CERN Document Server

    Tenkanen, Tommi

    2016-01-01

    We consider a scenario where the inflaton decays to a hidden sector thermally decoupled from the visible Standard Model sector. A tiny portal coupling between the hidden and the visible sectors later heats the visible sector so that the Standard Model degrees of freedom come to dominate the energy density of the Universe before Big Bang Nucleosynthesis. We find that this scenario is viable, although obtaining the correct dark matter abundance and retaining successful Big Bang Nucleosynthesis is not obvious. We also show that the isocurvature perturbations constituted by a primordial Higgs condensate are not problematic for the viability of the scenario.

  5. On Noncontextual, Non-Kolmogorovian Hidden Variable Theories

    Science.gov (United States)

    Feintzeig, Benjamin H.; Fletcher, Samuel C.

    2017-02-01

    One implication of Bell's theorem is that there cannot in general be hidden variable models for quantum mechanics that both are noncontextual and retain the structure of a classical probability space. Thus, some hidden variable programs aim to retain noncontextuality at the cost of using a generalization of the Kolmogorov probability axioms. We generalize a theorem of Feintzeig (Br J Philos Sci 66(4): 905-927, 2015) to show that such programs are committed to the existence of a finite null cover for some quantum mechanical experiments, i.e., a finite collection of probability zero events whose disjunction exhausts the space of experimental possibilities.

  6. Image Coding using Markov Models with Hidden States

    DEFF Research Database (Denmark)

    Forchhammer, Søren Otto

    1999-01-01

    The Cylinder Partially Hidden Markov Model (CPH-MM) is applied to lossless coding of bi-level images. The original CPH-MM is relaxed for the purpose of coding by not imposing stationarity, but otherwise the model description is the same.......The Cylinder Partially Hidden Markov Model (CPH-MM) is applied to lossless coding of bi-level images. The original CPH-MM is relaxed for the purpose of coding by not imposing stationarity, but otherwise the model description is the same....

  7. How to Find a Hidden World at the LHC

    CERN Document Server

    Wells, James D

    2008-01-01

    I discuss how the Large Hadron Collider era should broaden our view of particle physics research, and apply this thinking to the case of Hidden Worlds. I focus on one of the simplest representative cases of a Hidden World, and detail the rich implications it has for LHC physics, including universal suppression of Higgs boson production, trans-TeV heavy Higgs boson signatures, heavy-to-light Higgs boson decays, weakly coupled exotic gauge bosons, and Higgs boson decays to four fermions via light exotic gauge bosons. Some signatures may be accessible in the very early stages of collider operation, whereas others motivate a later high-lumonosity upgrade.

  8. 78 FR 17744 - Culturally Significant Objects Imported for Exhibition Determinations: “Maya: Hidden Worlds...

    Science.gov (United States)

    2013-03-22

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Maya: Hidden Worlds Revealed... determine that the objects to be included in the exhibition ``Maya: Hidden Worlds Revealed,'' imported...

  9. The Function and the Utilization of Hidden Curriculum in College English Teaching

    Institute of Scientific and Technical Information of China (English)

    张英

    2013-01-01

    Explore the nature of the hidden curriculum, and utilize the positive functions of hidden curriculum with theory on English teaching and psychological linguistics to obtain desirable effects in College English teaching.

  10. Games and Platform Decisions

    DEFF Research Database (Denmark)

    Hansen, Poul H. Kyvsgård; Mikkola, Juliana Hsuan

    2007-01-01

    is the application of on-line games in order to provide training for decision makers and in order to generate overview over the implications of platform decisions. However, games have to be placed in a context with other methods and we argue that a mixture of games, workshops, and simulations can provide improved...

  11. Creative Platform Learning (CPL)

    DEFF Research Database (Denmark)

    Christensen, Jonna Langeland; Hansen, Søren

    Creative Platform Learning (CPL) er en pædagogisk metode, der skaber foretagsomme og innovative elever, der kan anvende deres kreativitet til at lære nyt. Ifølge den nye skolereform skal Innovation og entreprenørskab tydeliggøres i alle fag. I CPL er det en integreret del af undervisningen...

  12. Games and Platform Decisions

    DEFF Research Database (Denmark)

    Hansen, Poul H. Kyvsgård; Mikkola, Juliana Hsuan

    2007-01-01

    is the application of on-line games in order to provide training for decision makers and in order to generate overview over the implications of platform decisions. However, games have to be placed in a context with other methods and we argue that a mixture of games, workshops, and simulations can provide improved...

  13. Low-scale gravity mediation in warped extra dimension and collider phenomenology on hidden sector

    Indian Academy of Sciences (India)

    H Itoh; N Okada; T Yamashita

    2007-11-01

    We propose a new scenario of gravity-mediated supersymmetry breaking (gravity mediation) in a supersymmetric Randall-Sundrum model, where the gravity mediation takes place at a low scale due to the warped metric. We investigate collider phenomenology involving the hidden sector field, and find a possibility that the hidden sector field can be produced at the LHC and the ILC. The hidden sector may no longer be hidden.

  14. Coarse-grained hidden entropy production in partially inaccessible quantum jump trajectories

    OpenAIRE

    Frenzel, Max F.; Sagawa, Takahiro

    2016-01-01

    We consider an open quantum system for which only a subset of all possible transitions are accessible, while the remaining ones are hidden from direct observation. Using a modification of the notion of quantum jump trajectories we introduce the coarse-grained hidden entropy, which quantifies the entropy production in the hidden subsystem conditioned on our observations of the visible part. The entropy production consisting of the sum of visible and coarse-grained hidden entropy is shown to sa...

  15. Photoacoustic imaging of hidden dental caries by using a fiber-based probing system

    Science.gov (United States)

    Koyama, Takuya; Kakino, Satoko; Matsuura, Yuji

    2017-04-01

    Photoacoustic method to detect hidden dental caries is proposed. It was found that high frequency ultrasonic waves are generated from hidden carious part when radiating laser light to occlusal surface of model tooth. By making a map of intensity of these high frequency components, photoacoustic images of hidden caries were successfully obtained. A photoacoustic imaging system using a bundle of hollow optical fiber was fabricated for using clinical application, and clear photoacoustic image of hidden caries was also obtained by this system.

  16. Mobile Platforms and Development Environments

    CERN Document Server

    Helal, Sumi; Li, Wengdong

    2012-01-01

    Mobile platform development has lately become a technological war zone with extremely dynamic and fluid movement, especially in the smart phone and tablet market space. This Synthesis lecture is a guide to the latest developments of the key mobile platforms that are shaping the mobile platform industry. The book covers the three currently dominant native platforms -- iOS, Android and Windows Phone -- along with the device-agnostic HTML5 mobile web platform. The lecture also covers location-based services (LBS) which can be considered as a platform in its own right. The lecture utilizes a sampl

  17. B-graph sampling to estimate the size of a hidden population

    NARCIS (Netherlands)

    Spreen, M.; Bogaerts, S.

    2015-01-01

    Link-tracing designs are often used to estimate the size of hidden populations by utilizing the relational links between their members. A major problem in studies of hidden populations is the lack of a convenient sampling frame. The most frequently applied design in studies of hidden populations is

  18. Inference with constrained hidden Markov models in PRISM

    DEFF Research Database (Denmark)

    Christiansen, Henning; Have, Christian Theil; Lassen, Ole Torp

    2010-01-01

    A Hidden Markov Model (HMM) is a common statistical model which is widely used for analysis of biological sequence data and other sequential phenomena. In the present paper we show how HMMs can be extended with side-constraints and present constraint solving techniques for efficient inference. De...

  19. Searching for a hidden sector in multiparticle production at LHC

    Directory of Open Access Journals (Sweden)

    Sanchis-Lozano Miguel-Angel

    2016-01-01

    Full Text Available A hidden sector beyond the Standard Model can show up in multiparticle production altering inclusive correlations and factorial cumulants of multiplicity distributions. In this report such a study is advocated with a special emphasis on the searches at LHC.

  20. Education as Text: The Varieties of Educational Hiddenness.

    Science.gov (United States)

    Gordon, David

    1988-01-01

    Using the ideas of Paul Ricoeur and Clifford Geertz, this article develops the notion of education as a "text" and analyzes the "hidden curriculum" of that text as it is read by all members of the society. The hypothesis is proposed that education becomes a text about society's myths and sacred beliefs. (TE)

  1. EVALUASI HIDDEN CURRICULUM DI SMP NEGERI BOJA, KABUPATEN KENDAL

    Directory of Open Access Journals (Sweden)

    Neni Lestari

    2015-12-01

    Full Text Available This study aimed to evaluate the implementation and impact of Hidden Curriculum, as well as the determinant factors of success and sustainability in SMPN 2 Boja Kendal. This study was an evaluative research using qualitative approach. The data collected by using observation, interviews, and documentation. Data analyzed by collecting and selecting to be deduce. Validity used triangulation data that combined the result of observation, interviews, and documentation. The results of the study were: 1 The activities of hidden curriculum development at SMPN 2 Boja Kendal, namely: flag ceremony, school environmental management, establishing and enforcing discipline, special religious worship, smiles, greetings and courtesies, exemplary, relationship among students and principal, teachers, and staff, school canteen services. 2 The impact of the hidden curriculum development was the changing of school community’s behavior being better, created clean and beautiful school environment, the improvement of public trust to the school toward their kids’ education. Development of the hidden curriculum could establish students good character and an optimal achievement as well as a good school culture. 3 Internal supporting factors including: qualified human resources, the availability of school facilities, school environment was clean and beautiful. External supporting factors occur in the form of endorsement of the parents, school committees and communities in establishing good and virtuous character for the students.

  2. Is the Hidden Curriculum a Relevant Issue in Educational Processes

    Directory of Open Access Journals (Sweden)

    Patarroyo Esther

    2004-08-01

    Full Text Available This paper explores some ideas about the hidden curriculum as an amount of ideas and beliefs which are implicit in an indirect way into the scholar life. Those ideas are regarding to gender equality, social status and racial difference, among others. We consider teachers are able to integrate the hidden curriculum as a pedagogical strategy in the classroom. Examples of integration include activities such as observation techniques, role-plays, peer modeling and particularly, the portfolio as a useful tool for reflection which reveals the hidden curriculum. Key words: Hidden Curriculum, Pedagogical Strategy, Portfolio, ELT Processes, Stereotypes Este documento explora algunas ideas acerca del currículo oculto como una suma de ideas y creencias que están implícitos de una forma indirecta dentro de la vida escolar. Estas ideas están relacionadas con la equidad de género, diferencias sociales y raciales, entre otros. Consideramos que es posible para los docentes integrar el currículo como estrategia pedagógica en el aula. Ejemplos de esta integración incluyen técnicas de observación, juegos de roles, modelamiento en parejas y particularmente, el portafolio como herramienta de reflexión que permita hacer evidente el currículo oculto. Palabras claves: Currículo Oculto, Estrategia Pedagógica, Estereotipos, Enseñanza de Inglés, Portafolio

  3. Multistability and hidden attractors in a relay system with hysteresis

    DEFF Research Database (Denmark)

    Zhusubaliyev, Zhanybai T.; Mosekilde, Erik; Rubanov, Vasily G.

    2015-01-01

    For nonlinear dynamic systems with switching control, the concept of a "hidden attractor" naturally applies to a stable dynamic state that either (1) coexists with the stable switching cycle or (2), if the switching cycle is unstable, has a basin of attraction that does not intersect with the nei...

  4. The Hidden Curriculum of Youth Policy: A Dutch Example

    NARCIS (Netherlands)

    Hopman, M.; De Winter, M.; Koops, W.

    2014-01-01

    Youth policy is more than a mere response to the actual behavior of children, but it is equally influenced by values and beliefs of policy makers. These values are however rarely made explicit and, therefore, the authors refer to them as “the hidden curriculum” of youth policy. The study investigati

  5. Searching for hidden sectors in multiparticle production at the LHC

    CERN Document Server

    Sanchis-Lozano, Miguel-Angel

    2016-01-01

    Most signatures of new physics in colliders have been studied so far on the transverse plane with respect to the beam direction. In this work however we study the impact of a hidden sector beyond the Standard Model (SM) on inclusive (pseudo)rapidity correlations and moments of the multiplicity distributions, with special emphasis in the LHC results.

  6. From epistemology to hidden curriculum: Critical vs. 'commercial' pedagogic perspective

    Directory of Open Access Journals (Sweden)

    Marojević Jovana C.

    2016-01-01

    Full Text Available Knowledge or, more precisely, its power is one of central themes in critical pedagogy. Since they are interested in school as the site of social critique, aimed at social transformations, critically oriented pedagogues pay special attention to the relation of knowledge and power or, to simplify it, the function of knowledge in the reproduction of the existing (often oppressive social relations. Not recognizing school as a mere site of social, economic or cultural preservation, they often study epistemology on which modern school is founded (positivistic epistemology and its hidden curriculum who function so that they legitimate social reproductive function of the school in a continuous cycle of self-justification. Since a certain understanding of knowledge and its function reveals the hidden curriculum of a certain educational philosophy, and since this consequently changes school into a site of social transformation or social transmission, viewed from the critical position this is the subject of the analysis of our paper. By final sublimation and contrasting the opposite positivistic and critical positions we conclude that the hidden curriculum of the first is the curriculum of the soliloquies while the curriculum of the second, critical tendency is entirely of a dialogue nature. It is clear that uni-directedness of the hidden curriculum formed according the postulates of positivistic epistemology can contribute only to positivistic transmission and regeneration of the existing social order, while the discursivity of critically oriented school defines the relation towards society as two-way, transformational, active and emancipatory.

  7. K­MEANS CLUSTERING FOR HIDDEN MARKOV MODEL

    NARCIS (Netherlands)

    Perrone, M.P.; Connell, S.D.

    2004-01-01

    An unsupervised k­means clustering algorithm for hidden Markov models is described and applied to the task of generating subclass models for individual handwritten character classes. The algorithm is compared to a related clustering method and shown to give a relative change in the error rate of as

  8. Hidden symmetry of the quantum Calogero-Moser system

    DEFF Research Database (Denmark)

    Kuzentsov, Vadim b

    1996-01-01

    The hidden symmetry of the quantum Calogero-Moser system with an inverse-square potential is algebraically demonstrated making use of Dunkl's operators. We find the underlying algebra explaining the super-integrability phenomenon for this system. Applications to related multi-variable Bessel...

  9. Thermoelectric generator hidden in a shirt with a fabric radiator

    Science.gov (United States)

    Leonov, Vladimir; Vullers, Ruud J. M.; Hoof, Chris Van

    2012-06-01

    Integration of thermopiles in garments has been performed in this work in different ways. It is shown that textile has a minor effect on power generation, which enables completely hidden and unobtrusive energy harvester. A one-milliwatt thermoelectric generator is then integrated between two layers of a shirt and its characteristics are reported.

  10. Discriminative training of self-structuring hidden control neural models

    DEFF Research Database (Denmark)

    Sørensen, Helge Bjarup Dissing; Hartmann, Uwe; Hunnerup, Preben

    1995-01-01

    This paper presents a new training algorithm for self-structuring hidden control neural (SHC) models. The SHC models were trained non-discriminatively for speech recognition applications. Better recognition performance can generally be achieved, if discriminative training is applied instead. Thus...

  11. Old, New and Hidden Causes of Perioperative Hypersensitivity.

    Science.gov (United States)

    Garvey, Lene Heise

    2016-01-01

    Perioperative hypersensitivity reactions are rare, often life-threatening events, and subsequent investigations to identify the culprit are important to avoid re-exposure. All exposures in the perioperative setting may potentially be the cause of a hypersensitivity reaction, but drugs administered intravenously such as neuromuscular blocking agents (NMBA), induction agents and antibiotics have traditionally been reported to be implicated most commonly. It has recently become apparent that there are geographical differences in sensitization patterns related to variation in exposures, referral patterns and performance and interpretation of investigations. Differences in sensitization to NMBAs are partly explained by cross sensitization to pholcodine, an ingredient in cough-medicines available in some countries. While NMBAs are the most common causes of perioperative hypersensitivity in some countries, this may not necessarily be the case in all countries. New and hidden allergens have emerged as causes of perioperative hypersensitivity such as blue dyes, chlorhexidine and excipients. Detailed knowledge of the events at the time of reaction is necessary to identify potential culprits including rare and hidden allergens. Cooperation between allergists and anaesthetists, or other staff present perioperatively, is often needed to identify hidden or even undocumented exposures. The objectives of this review are to provide an overview of the history of investigation of perioperative hypersensitivity, to describe the differences in causes of perioperative hypersensitivity emerging over time and to increase awareness about the "hidden allergens" in the perioperative setting. Some practical advice on how to approach the patient testing negative on all initial investigations is also included.

  12. Parameter estimation of hidden periodic model in random fields

    Institute of Scientific and Technical Information of China (English)

    何书元

    1999-01-01

    Two-dimensional hidden periodic model is an important model in random fields. The model is used in the field of two-dimensional signal processing, prediction and spectral analysis. A method of estimating the parameters for the model is designed. The strong consistency of the estimators is proved.

  13. Beyond the hidden curriculum: The challenging search for authentic ...

    African Journals Online (AJOL)

    2013-11-01

    Nov 1, 2013 ... [6] It was erroneously assumed that medical students ... hidden curriculum, therefore, demands an authentic and comprehensive enquiry into the concept of human dignity, ... reasoning that underpins the desirable values-based healthcare. ... and highly interpersonal form of teaching and learning that takes.

  14. Hidden conic quadratic representation of some nonconvex quadratic optimization problems

    NARCIS (Netherlands)

    Ben-Tal, A.; den Hertog, D.

    2014-01-01

    The problem of minimizing a quadratic objective function subject to one or two quadratic constraints is known to have a hidden convexity property, even when the quadratic forms are indefinite. The equivalent convex problem is a semidefinite one, and the equivalence is based on the celebrated S-lemma

  15. Recognizing Strokes in Tennis Videos Using Hidden Markov Models

    NARCIS (Netherlands)

    Petkovic, M.; Jonker, W.; Zivkovic, Z.

    2001-01-01

    This paper addresses content-based video retrieval with an emphasis on recognizing events in tennis game videos. In particular, we aim at recognizing different classes of tennis strokes using automatic learning capability of Hidden Markov Models. Driven by our domain knowledge, a robust player segme

  16. A Constraint Model for Constrained Hidden Markov Models

    DEFF Research Database (Denmark)

    Christiansen, Henning; Have, Christian Theil; Lassen, Ole Torp

    2009-01-01

    A Hidden Markov Model (HMM) is a common statistical model which is widely used for analysis of biological sequence data and other sequential phenomena. In the present paper we extend HMMs with constraints and show how the familiar Viterbi algorithm can be generalized, based on constraint solving...

  17. Evolving the Topology of Hidden Markov Models using Evolutionary Algorithms

    DEFF Research Database (Denmark)

    Thomsen, Réne

    2002-01-01

    Hidden Markov models (HMM) are widely used for speech recognition and have recently gained a lot of attention in the bioinformatics community, because of their ability to capture the information buried in biological sequences. Usually, heuristic algorithms such as Baum-Welch are used to estimate...

  18. Exposing the Hidden-Web Induced by Ajax

    NARCIS (Netherlands)

    Mesbah, A.; Van Deursen, A.

    2008-01-01

    AJAX is a very promising approach for improving rich interactivity and responsiveness of web applications. At the same time, AJAX techniques increase the totality of the hidden web by shattering the metaphor of a web ‘page’ upon which general search engines are based. This paper describes a techniqu

  19. Exposing the Hidden-Web Induced by Ajax

    NARCIS (Netherlands)

    Mesbah, A.; Van Deursen, A.

    2008-01-01

    AJAX is a very promising approach for improving rich interactivity and responsiveness of web applications. At the same time, AJAX techniques increase the totality of the hidden web by shattering the metaphor of a web ‘page’ upon which general search engines are based. This paper describes a

  20. Optical Test of Local Hidden-Variable Model

    Institute of Scientific and Technical Information of China (English)

    WU XiaoHua; ZONG HongShi; PANG HouRong

    2001-01-01

    An inequality is deduced from local realism and a supplementary assumption. This inequality defines an experiment that can be actually performed with the present technology to test local hidden-variable models, and it is violated by quantum mechanics with a factor 1.92, while it can be simplified into a form where just two measurements are required.``

  1. New Caledonian crows reason about hidden causal agents.

    Science.gov (United States)

    Taylor, Alex H; Miller, Rachael; Gray, Russell D

    2012-10-02

    The ability to make inferences about hidden causal mechanisms underpins scientific and religious thought. It also facilitates the understanding of social interactions and the production of sophisticated tool-using behaviors. However, although animals can reason about the outcomes of accidental interventions, only humans have been shown to make inferences about hidden causal mechanisms. Here, we show that tool-making New Caledonian crows react differently to an observable event when it is caused by a hidden causal agent. Eight crows watched two series of events in which a stick moved. In the first set of events, the crows observed a human enter a hide, a stick move, and the human then leave the hide. In the second, the stick moved without a human entering or exiting the hide. The crows inspected the hide and abandoned probing with a tool for food more often after the second, unexplained series of events. This difference shows that the crows can reason about a hidden causal agent. Comparative studies with the methodology outlined here could aid in elucidating the selective pressures that led to the evolution of this cognitive ability.

  2. Thermoelectric generator hidden in a shirt with a fabric radiator

    NARCIS (Netherlands)

    Leonov, V.; Vullers, R.J.M.; Hoof, C.V.

    2012-01-01

    Integration of thermopiles in garments has been performed in this work in different ways. It is shown that textile has a minor effect on power generation, which enables completely hidden and unobtrusive energy harvester. A one-milliwatt thermoelectric generator is then integrated between two layers

  3. Search for dark photons from supersymmetric hidden valleys

    NARCIS (Netherlands)

    Abazov, V.M.; et al., [Unknown; Ancu, L.S.; de Jong, S.J.; Filthaut, F.; Galea, C.F.; Hegeman, J.G.; Houben, P.; Meijer, M.M.; Svoisky, P.; van den Berg, P.J.; van Leeuwen, W.M.

    2009-01-01

    We search for a new light gauge boson, a dark photon, with the D0 experiment. In the model we consider, supersymmetric partners are pair produced and cascade to the lightest neutralinos that can decay into the hidden sector state plus either a photon or a dark photon. The dark photon decays through

  4. Education as Text: The Varieties of Educational Hiddenness.

    Science.gov (United States)

    Gordon, David

    1988-01-01

    Using the ideas of Paul Ricoeur and Clifford Geertz, this article develops the notion of education as a "text" and analyzes the "hidden curriculum" of that text as it is read by all members of the society. The hypothesis is proposed that education becomes a text about society's myths and sacred beliefs. (TE)

  5. Simple yet Hidden Counterexamples in Undergraduate Real Analysis

    Science.gov (United States)

    Shipman, Barbara A.; Shipman, Patrick D.

    2013-01-01

    We study situations in introductory analysis in which students affirmed false statements as true, despite simple counterexamples that they easily recognized afterwards. The study draws attention to how simple counterexamples can become hidden in plain sight, even in an active learning atmosphere where students proposed simple (as well as more…

  6. Local clustering in scale-free networks with hidden variables

    Science.gov (United States)

    van der Hofstad, Remco; Janssen, A. J. E. M.; van Leeuwaarden, Johan S. H.; Stegehuis, Clara

    2017-02-01

    We investigate the presence of triangles in a class of correlated random graphs in which hidden variables determine the pairwise connections between vertices. The class rules out self-loops and multiple edges. We focus on the regime where the hidden variables follow a power law with exponent τ ∈(2 ,3 ) , so that the degrees have infinite variance. The natural cutoff hc characterizes the largest degrees in the hidden variable models, and a structural cutoff hs introduces negative degree correlations (disassortative mixing) due to the infinite-variance degrees. We show that local clustering decreases with the hidden variable (or degree). We also determine how the average clustering coefficient C scales with the network size N , as a function of hs and hc. For scale-free networks with exponent 2 universality class at hand. We characterize the extremely slow decay of C when τ ≈2 and show that for τ =2.1 , say, clustering starts to vanish only for networks as large as N =109 .

  7. On local-hidden-variable no-go theorems

    Science.gov (United States)

    Methot, A. A.

    2006-06-01

    The strongest attack against quantum mechanics came in 1935 in the form of a paper by Einstein, Podolsky, and Rosen. It was argued that the theory of quantum mechanics could not be called a complete theory of Nature, for every element of reality is not represented in the formalism as such. The authors then put forth a proposition: we must search for a theory where, upon knowing everything about the system, including possible hidden variables, one could make precise predictions concerning elements of reality. This project was ultimately doomed in 1964 with the work of Bell, who showed that the most general local hidden variable theory could not reproduce correlations that arise in quantum mechanics. There exist mainly three forms of no-go theorems for local hidden variable theories. Although almost every physicist knows the consequences of these no-go theorems, not every physicist is aware of the distinctions between the three or even their exact definitions. Thus, we will discuss here the three principal forms of no-go theorems for local hidden variable theories of Nature. We will define Bell theorems, Bell theorems without inequalities, and pseudo-telepathy. A discussion of the similarities and differences will follow.

  8. Thermoelectric generator hidden in a shirt with a fabric radiator

    NARCIS (Netherlands)

    Leonov, V.; Vullers, R.J.M.; Hoof, C.V.

    2012-01-01

    Integration of thermopiles in garments has been performed in this work in different ways. It is shown that textile has a minor effect on power generation, which enables completely hidden and unobtrusive energy harvester. A one-milliwatt thermoelectric generator is then integrated between two layers

  9. Isovector and hidden-beauty partners of the X(3872)

    CERN Document Server

    Hogaasen, Hallstein; Richard, Jean-Marc; Sorba, Paul

    2014-01-01

    The isovector partners of the X(3872), recently found at BES III, Belle and CLEO-c were predicted in a simple model based on the chromomagnetic interaction among quarks (H. Hogaasen, J-M. Richard and P. Sorba, Phys. Rev. D73, 054013, 2006). The extension to the hidden-beauty sector is discussed.

  10. Bayesian online algorithms for learning in discrete Hidden Markov Models

    OpenAIRE

    Alamino, Roberto C.; Caticha, Nestor

    2008-01-01

    We propose and analyze two different Bayesian online algorithms for learning in discrete Hidden Markov Models and compare their performance with the already known Baldi-Chauvin Algorithm. Using the Kullback-Leibler divergence as a measure of generalization we draw learning curves in simplified situations for these algorithms and compare their performances.

  11. A novel design of hidden web crawler using ontology

    OpenAIRE

    Manvi; Bhatia, Komal Kumar; Dixit, Ashutosh

    2015-01-01

    Deep Web is content hidden behind HTML forms. Since it represents a large portion of the structured, unstructured and dynamic data on the Web, accessing Deep-Web content has been a long challenge for the database community. This paper describes a crawler for accessing Deep-Web using Ontologies. Performance evaluation of the proposed work showed that this new approach has promising results.

  12. Improved Medication Adherence and Frequency of Blood Glucose Self-Testing using an m-Health Platform Versus Usual Care in a Multisite Randomized Clinical Trial Among People with Type 2 Diabetes in India.

    Science.gov (United States)

    Kleinman, Nora J; Shah, Avani; Shah, Sanjiv; Phatak, Sanjeev; Viswanathan, Vijay

    2017-03-06

    In 2015, India had an estimated 69.2 million people with diabetes and a national prevalence of 8.7%. Evidence is mounting for the benefits of telemedicine in diabetes care, but remains limited on mobile-health (m-Health) interventions. This study assessed the impact of an m-Health diabetes platform on clinical outcomes, patient-reported outcomes, patient and provider satisfaction, and app usage. This open-label, two-arm parallel study enrolled 91 people at 3 sites in India, aged 18-65, with type 2 diabetes, and an A1c between 7.5% and 12.5% (58-113 mmol/mol). Participants were randomly assigned 1:1 to m-Health or usual care and observed for 6 months. All received free visits, laboratory tests, transportation fees, and strips and lancets. Intervention participants received the m-Health app and a mobile phone data stipend. A1c change was previously reported as statistically significant. Significantly more participants in intervention than control had improved medication adherence (39.0% vs. 12.8%; p = 0.03) and increased frequency of blood glucose (BG) self-testing (39.0% vs. 10.3%; p = 0.01) at 6 months from baseline. No other outcomes were significantly different. Among m-Health users, 75% of participants actively used the app at week 24. Participants entered 29,668 medications and 2,575 BG readings, sent 497 messages, and received 890 messages. Most participants (80%) were satisfied with all aspects of the app and all seven providers rated the software very acceptable. Participants assigned to m-Health had increased medication adherence and frequency of BG testing compared with usual care participants. This tool could be an effective way to expand access to quality chronic disease care and improve outcomes.

  13. Knowledge Discovery for Smart Grid Operation, Control, and Situation Awareness -- A Big Data Visualization Platform

    Energy Technology Data Exchange (ETDEWEB)

    Gu, Yi; Jiang, Huaiguang; Zhang, Yingchen; Zhang, Jun Jason; Gao, Tianlu; Muljadi, Eduard

    2016-11-21

    In this paper, a big data visualization platform is designed to discover the hidden useful knowledge for smart grid (SG) operation, control and situation awareness. The spawn of smart sensors at both grid side and customer side can provide large volume of heterogeneous data that collect information in all time spectrums. Extracting useful knowledge from this big-data poll is still challenging. In this paper, the Apache Spark, an open source cluster computing framework, is used to process the big-data to effectively discover the hidden knowledge. A high-speed communication architecture utilizing the Open System Interconnection (OSI) model is designed to transmit the data to a visualization platform. This visualization platform uses Google Earth, a global geographic information system (GIS) to link the geological information with the SG knowledge and visualize the information in user defined fashion. The University of Denver's campus grid is used as a SG test bench and several demonstrations are presented for the proposed platform.

  14. 旋转平台与固定平台在全膝关节置换术中的随机临床试验:五年内无临床检测差异%Randomized clinical trial of rotating-platform and fixed-bearing in total knee arthroplasty:no clini-cally differences at five years

    Institute of Scientific and Technical Information of China (English)

    宋星来; 任姜栋; 吾胡孜·吾拉木; 张晓岗

    2016-01-01

    included in this prospective randomized controlled trial. They were randomly divided into fixed⁃bearing group (70 cases, using a fixed platform prosthesis) and rotating⁃platform group (70 cases, using a rotating platform prosthesis). The operation time, complications and implant survival rate of two groups were recorded, and the American Knee Society (AKS) knee score system was used to evaluate the knee function of patients at 6th month, and 1st, 2nd, 5th year postoperatively. The radio⁃graphs were taken at the same time. Results Sixty⁃six cases in the rotating⁃platform group and 61 in the fixed⁃bearing group were followed up for 5 years. There was one revision in fixed⁃bearing group because of infection, and one in rotating⁃platform group due to aseptic loosening. There was 1 case of deep vein thrombosis, 1 case of patellar fracture, 1 case of knee joint dislocation and 1 case of unexplained knee snapping in fixed⁃bearing group, and there were 3 cases of unexplained knee snapping in rotating⁃platform group. Knee maximum range of motion at 5th year postoperatively in the rotating⁃platform group was 109.8° ± 8.1° , the functional score was 68.7 ± 14.3, the pain scores was 37.8 ± 4.3, and the stair climbing scores were 35.8 ± 10.1. Knee maximum range of motion at 5th year postoperatively in the rotating⁃platform group was 110.4°±5.5°, the functional scores were 69.9 ± 17.2, the pain scores was 38.1 ± 5.0, and the stair climbing scores were 37.5 ± 11.0. There was no signifi⁃ cantly differences between two groups in all above indexes at every time point (P>0.05 for all). Conclusion In this randomized clinical trial, the rotating⁃platform total knee design did not provide better maximum knee flexion, better function, or better durability at 5th year postoperatively than a posterior⁃stabilized, fixed⁃bearing design.

  15. Baryon states with hidden charm in the extended local hidden gauge approach

    Energy Technology Data Exchange (ETDEWEB)

    Uchino, T.; Oset, E. [Centro Mixto Universidad de Valencia-CSIC, Institutos de Investigacion de Paterna, Departamento de Fisica Teorica y IFIC, Valencia (Spain); Liang, Wei-Hong [Guangxi Normal University, Department of Physics, Guilin (China)

    2016-03-15

    The s-wave interaction of anti DΛ{sub c}, anti DΣ{sub c}, anti D{sup *}Λ{sub c}, anti D{sup *}Σ{sub c} and anti DΣ{sub c}{sup *}, anti D{sup *}Σ{sub c}{sup *}, is studied within a unitary coupled channels scheme with the extended local hidden gauge approach. In addition to the Weinberg-Tomozawa term, several additional diagrams via the pion exchange are also taken into account as box potentials. Furthermore, in order to implement the full coupled channels calculation, some of the box potentials which mix the vector-baryon and pseudoscalar-baryon sectors are extended to construct the effective transition potentials. As a result, we have observed six possible states in several angular momenta. Four of them correspond to two pairs of admixture states, two of anti DΣ{sub c} - anti D{sup *}Σ{sub c} with J = 1/2, and two of anti DΣ{sub c}{sup *} - anti D{sup *}Σ{sub c}{sup *} with J = 3/2. Moreover, we find a anti D{sup *}Σ{sub c} resonance which couples to the anti DΛ{sub c} channel and one spin degenerated bound state of anti D{sup *}Σ{sub c}{sup *} with J = 1/2,5/2. (orig.)

  16. Hidden Owners, Hidden Profits, and Poor Nursing Home Care: A Case Study.

    Science.gov (United States)

    Harrington, Charlene; Ross, Leslie; Kang, Taewoon

    2015-01-01

    The study examined the ownership transparency, financial accountability, and quality indicators of a regional for-profit nursing home chain in California, using a case study methodology to analyze data on the chain's ownership and management structure, financial data, staffing levels, deficiencies and complaints, and litigation. Secondary data were obtained from regulatory and cost reports and litigation cases. Qualitative descriptions of ownership and management were presented and quantitative analyses were conducted by comparing financial and quality indicators with other California for-profit chains, for-profit non-chains, and nonprofit nursing home groups in 2011. The chain's complex, interlocking individual and corporate owners and property companies obscured its ownership structure and financial arrangements. Nursing and support services expenditures were lower than nonprofits and administrative costs were higher than for-profit non-chains. The chain's nurse staffing was lower than expected staffing levels; its deficiencies and citations were higher than in nonprofits; and a number of lawsuits resulted in bankruptcy. Profits were hidden in the chain's management fees, lease agreements, interest payments to owners, and purchases from related-party companies. Greater ownership transparency and financial accountability requirements are needed to ensure regulatory oversight and quality of care.

  17. Maximizing scientific knowledge from randomized clinical trials

    DEFF Research Database (Denmark)

    Gustafsson, Finn; Atar, Dan; Pitt, Bertram;

    2010-01-01

    Trialists have an ethical and financial responsibility to plan and conduct clinical trials in a manner that will maximize the scientific knowledge gained from the trial. However, the amount of scientific information generated by randomized clinical trials in cardiovascular medicine is highly...... variable. Generation of trial databases and/or biobanks originating in large randomized clinical trials has successfully increased the knowledge obtained from those trials. At the 10th Cardiovascular Trialist Workshop, possibilities and pitfalls in designing and accessing clinical trial databases were......, in particular with respect to collaboration with the trial sponsor and to analytic pitfalls. The advantages of creating screening databases in conjunction with a given clinical trial are described; and finally, the potential for posttrial database studies to become a platform for training young scientists...

  18. Online stock trading platform

    Directory of Open Access Journals (Sweden)

    Ion LUNGU

    2006-01-01

    Full Text Available The Internet is the perfect tool that can assure the market’s transparency for any user who wants to trade on the stock market. The investor can have access to the market news, financial calendar or the press releases of the issuers. A good online trading platform also provides real-time intraday quotes, trading history and technical analysis giving the investor a clearer view of the supply and demand in the market. All this information provides the investor a good image of the market and encourages him to trade. This paper wishes to draft the pieces of an online trading platform and to analyze the impact of developing and implementing one in a brokerage firm.

  19. Available: motorised platform

    CERN Document Server

    The COMPASS collaboration

    2014-01-01

    The COMPASS collaboration would like to offer to a new owner the following useful and fully operational piece of equipment, which is due to be replaced with better adapted equipment.   Please contact Erwin Bielert (erwin.bielert@cern.ch or 160539) for further information.  Motorized platform (FOR FREE):   Fabricated by ACL (Alfredo Cardoso & Cia Ltd) in Portugal. The model number is MeXs 5-­‐30.  Specifications: 5 m wide, 1 m deep, adjustable height (1.5 m if folded). Maximum working floor height: 4 m. conforms to CERN regulations, number LV158. Type LD500, capacity 500 kg and weight 2000 kg.  If no interested party is found before December 2014, the platform will be thrown away.

  20. Common tester platform concept.

    Energy Technology Data Exchange (ETDEWEB)

    Hurst, Michael James

    2008-05-01

    This report summarizes the results of a case study on the doctrine of a common tester platform, a concept of a standardized platform that can be applicable across the broad spectrum of testing requirements throughout the various stages of a weapons program, as well as across the various weapons programs. The common tester concept strives to define an affordable, next-generation design that will meet testing requirements with the flexibility to grow and expand; supporting the initial development stages of a weapons program through to the final production and surveillance stages. This report discusses a concept investing key leveraging technologies and operational concepts combined with prototype tester-development experiences and practical lessons learned gleaned from past weapons programs.

  1. OGC Collaborative Platform undercover

    Science.gov (United States)

    Buehler, G.; Arctur, D. K.; Bermudez, L. E.

    2012-12-01

    The mission of the Open Geospatial Consortium (OGC) is to serve as a global forum for the collaboration of developers and users of spatial data products and services, and to advance the development of international standards for geospatial interoperability. The OGC coordinates with over 400 institutions in the development of geospatial standards. OGC has a dedicated staff supported by a Collaborative Web Platform to enable sophisticated and successful coordination among its members. Since its origins in the early 1990s, the OGC Collaborative Web Platform has evolved organically to be the collaboration hub for standards development in the exchange of geospatial and related types of information, among a global network of thousands of technical, scientific and management professionals spanning numerous disparate application domains. This presentation describes the structure of this collaboration hub, the relationships enabled (both among and beyond OGC members), and how this network fits in a broader ecosystem of technology development and information standards organizations.

  2. Video analysis platform

    OpenAIRE

    FLORES, Pablo; Arias, Pablo; Lecumberry, Federico; Pardo, Álvaro

    2006-01-01

    In this article we present the Video Analysis Platform (VAP) which is an open source software framework for video analysis, processing and description. The main goals of VAP are: to provide a multiplatform system which allows the easy implementation of video algorithms, provide structures and algorithms for the segmentation of video data in its different levels of abstraction: shots, frames, objects, regions, etc, permit the generation and comparison of MPEG7-like descriptors, and develop tes...

  3. Cloud Robotics Platforms

    Directory of Open Access Journals (Sweden)

    Busra Koken

    2015-01-01

    Full Text Available Cloud robotics is a rapidly evolving field that allows robots to offload computation-intensive and storage-intensive jobs into the cloud. Robots are limited in terms of computational capacity, memory and storage. Cloud provides unlimited computation power, memory, storage and especially collaboration opportunity. Cloud-enabled robots are divided into two categories as standalone and networked robots. This article surveys cloud robotic platforms, standalone and networked robotic works such as grasping, simultaneous localization and mapping (SLAM and monitoring.

  4. HPC - Platforms Penta Chart

    Energy Technology Data Exchange (ETDEWEB)

    Trujillo, Angelina Michelle [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-10-08

    Strategy, Planning, Acquiring- very large scale computing platforms come and go and planning for immensely scalable machines often precedes actual procurement by 3 years. Procurement can be another year or more. Integration- After Acquisition, machines must be integrated into the computing environments at LANL. Connection to scalable storage via large scale storage networking, assuring correct and secure operations. Management and Utilization – Ongoing operations, maintenance, and trouble shooting of the hardware and systems software at massive scale is required.

  5. IP Rights and Technological Platforms

    OpenAIRE

    Robert P. Merges

    2008-01-01

    This paper is about intellectual property rights (IPRs) and platform technologies. After a brief introduction explaining some basics of networks, standards and platforms, I turn to three policy issues. The first is the role of IP in what might be termed platform policies, the decisions by courts and regulators concerning whether and how to promote multi-party access to important digital platforms such as media player hardware, cell phones, PCs, and the like. I argue that for the most part the...

  6. "Platform switching": Serendipity

    Directory of Open Access Journals (Sweden)

    N Kalavathy

    2014-01-01

    Full Text Available Implant dentistry is the latest developing field in terms of clinical techniques, research, material science and oral rehabilitation. Extensive work is being done to improve the designing of implants in order to achieve better esthetics and function. The main drawback with respect to implant restoration is achieving good osseointegration along with satisfactory stress distribution, which in turn will improve the prognosis of implant prosthesis by reducing the crestal bone loss. Many concepts have been developed with reference to surface coating of implants, surgical techniques for implant placement, immediate and delayed loading, platform switching concept, etc. This article has made an attempt to review the concept of platform switching was in fact revealed accidentally due to the nonavailability of the abutment appropriate to the size of the implant placed. A few aspect of platform switching, an upcoming idea to reduce crestal bone loss have been covered. The various methods used for locating and preparing the data were done through textbooks, Google search and related articles.

  7. "Platform switching": serendipity.

    Science.gov (United States)

    Kalavathy, N; Sridevi, J; Gehlot, Roshni; Kumar, Santosh

    2014-01-01

    Implant dentistry is the latest developing field in terms of clinical techniques, research, material science and oral rehabilitation. Extensive work is being done to improve the designing of implants in order to achieve better esthetics and function. The main drawback with respect to implant restoration is achieving good osseointegration along with satisfactory stress distribution, which in turn will improve the prognosis of implant prosthesis by reducing the crestal bone loss. Many concepts have been developed with reference to surface coating of implants, surgical techniques for implant placement, immediate and delayed loading, platform switching concept, etc. This article has made an attempt to review the concept of platform switching was in fact revealed accidentally due to the nonavailability of the abutment appropriate to the size of the implant placed. A few aspect of platform switching, an upcoming idea to reduce crestal bone loss have been covered. The various methods used for locating and preparing the data were done through textbooks, Google search and related articles.

  8. The Prodiguer Messaging Platform

    Science.gov (United States)

    Denvil, S.; Greenslade, M. A.; Carenton, N.; Levavasseur, G.; Raciazek, J.

    2015-12-01

    CONVERGENCE is a French multi-partner national project designed to gather HPC and informatics expertise to innovate in the context of running French global climate models with differing grids and at differing resolutions. Efficient and reliable execution of these models and the management and dissemination of model output are some of the complexities that CONVERGENCE aims to resolve.At any one moment in time, researchers affiliated with the Institut Pierre Simon Laplace (IPSL) climate modeling group, are running hundreds of global climate simulations. These simulations execute upon a heterogeneous set of French High Performance Computing (HPC) environments. The IPSL's simulation execution runtime libIGCM (library for IPSL Global Climate Modeling group) has recently been enhanced so as to support hitherto impossible realtime use cases such as simulation monitoring, data publication, metrics collection, simulation control, visualizations … etc. At the core of this enhancement is Prodiguer: an AMQP (Advanced Message Queue Protocol) based event driven asynchronous distributed messaging platform. libIGCM now dispatches copious amounts of information, in the form of messages, to the platform for remote processing by Prodiguer software agents at IPSL servers in Paris. Such processing takes several forms: Persisting message content to database(s); Launching rollback jobs upon simulation failure; Notifying downstream applications; Automation of visualization pipelines; We will describe and/or demonstrate the platform's: Technical implementation; Inherent ease of scalability; Inherent adaptiveness in respect to supervising simulations; Web portal receiving simulation notifications in realtime.

  9. Platform computing powers enterprise grid

    CERN Multimedia

    2002-01-01

    Platform Computing, today announced that the Stanford Linear Accelerator Center is using Platform LSF 5, to carry out groundbreaking research into the origins of the universe. Platform LSF 5 will deliver the mammoth computing power that SLAC's Linear Accelerator needs to process the data associated with intense high-energy physics research (1 page).

  10. The Geohazards Exploitation Platform

    Science.gov (United States)

    Laur, Henri; Casu, Francesco; Bally, Philippe; Caumont, Hervé; Pinto, Salvatore

    2016-04-01

    The Geohazards Exploitation Platform, or Geohazards TEP (GEP), is an ESA originated R&D activity of the EO ground segment to demonstrate the benefit of new technologies for large scale processing of EO data. This encompasses on-demand processing for specific user needs, systematic processing to address common information needs of the geohazards community, and integration of newly developed processors for scientists and other expert users. The platform supports the geohazards community's objectives as defined in the context of the International Forum on Satellite EO and Geohazards organised by ESA and GEO in Santorini in 2012. The GEP is a follow on to the Supersites Exploitation Platform (SSEP) an ESA initiative to support the Geohazards Supersites & Natural Laboratories initiative (GSNL). Today the GEP allows to exploit 70+ Terabyte of ERS and ENVISAT archive and the Copernicus Sentinel-1 data available on line. The platform has already engaged 22 European early adopters in a validation activity initiated in March 2015. Since September, this validation has reached 29 single user projects. Each project is concerned with either integrating an application, running on demand processing or systematically generating a product collection using an application available in the platform. The users primarily include 15 geoscience centres and universities based in Europe: British Geological Survey (UK), University of Leeds (UK), University College London (UK), ETH University of Zurich (CH), INGV (IT), CNR-IREA and CNR-IRPI (IT), University of L'Aquila (IT), NOA (GR), Univ. Blaise Pascal & CNRS (FR), Ecole Normale Supérieure (FR), ISTERRE / University of Grenoble-Alpes (FR). In addition, there are users from Africa and North America with the University of Rabat (MA) and the University of Miami (US). Furthermore two space agencies and four private companies are involved: the German Space Research Centre DLR (DE), the European Space Agency (ESA), Altamira Information (ES

  11. Identification of platform levels

    DEFF Research Database (Denmark)

    Mortensen, Niels Henrik

    2005-01-01

    reduction, ability to launch a wider product portfolio without increasing resources and reduction of complexity within the whole company. To support the multiple product development process, platform based product development has in many companies such as Philips, VW, Ford etc. proven to be a very effective...... and efficient tool. Transforming product development from single to multiple product development is a significant change in product development often involving major changes of product models, procedures and organization. In the area of product models a set of new models has to be introduced, e.g. models...

  12. Engineering of Algorithms for Hidden Markov models and Tree Distances

    DEFF Research Database (Denmark)

    Sand, Andreas

    grown exponentially because of drastic improvements in the technology behind DNA and RNA sequencing, and focus on the research field has increased due to its potential to expand our knowledge about biological mechanisms and to improve public health. There has therefore been a continuously growing demand...... of the algorithms to exploit the parallel architecture of modern computers. In this PhD dissertation, I present my work with algorithmic optimizations and parallelizations in primarily two areas in algorithmic bioinformatics: algorithms for analyzing hidden Markov models and algorithms for computing distance...... measures between phylogenetic trees. Hidden Markov models is a class of probabilistic models that is used in a number of core applications in bioinformatics such as modeling of proteins, gene finding and reconstruction of species and population histories. I show how a relatively simple parallelization can...

  13. Extraction of hidden information by efficient community detection in networks

    CERN Document Server

    Lee, Juyong; Lee, Jooyoung

    2012-01-01

    Currently, we are overwhelmed by a deluge of experimental data, and network physics has the potential to become an invaluable method to increase our understanding of large interacting datasets. However, this potential is often unrealized for two reasons: uncovering the hidden community structure of a network, known as community detection, is difficult, and further, even if one has an idea of this community structure, it is not a priori obvious how to efficiently use this information. Here, to address both of these issues, we, first, identify optimal community structure of given networks in terms of modularity by utilizing a recently introduced community detection method. Second, we develop an approach to use this community information to extract hidden information from a network. When applied to a protein-protein interaction network, the proposed method outperforms current state-of-the-art methods that use only the local information of a network. The method is generally applicable to networks from many areas.

  14. Effectiveness of AODV Protocol under Hidden Node Environment

    Science.gov (United States)

    Garg, Ruchi; Sharma, Himanshu; Kumar, Sumit

    IEEE 802.11 is a standard for mobile ad hoc networks (MANET), implemented with various different protocols. Ad Hoc on Demand Distance Vector Routing (AODV) is one of the several protocols of IEEE 802.11, intended to provide various Quality of Service (QOS) parameters under acceptable range. To avoid the collision and interference the MAC protocol has only two solutions, one, to sense the physical carrier and second, to use the RTS/CTS handshake mechanism. But with the help of these methods AODV is not free from the problem of hidden nodes like other several protocols. Under the hidden node environment, performance of AODV depends upon various factors. The position of receiver and sender among the other nodes is very crucial and it affects the performance. Under the various situations the AODV is simulated with the help of NS2 and the outcomes are discussed.

  15. Perpetual points and hidden attractors in dynamical systems

    Energy Technology Data Exchange (ETDEWEB)

    Dudkowski, Dawid, E-mail: dawid.dudkowski@p.lodz.pl [Division of Dynamics, Technical University of Lodz, Stefanowskiego 1/15, 90-924 Lodz (Poland); Prasad, Awadhesh [Department of Physics and Astrophysics, University of Delhi, Delhi 110007 (India); Kapitaniak, Tomasz [Division of Dynamics, Technical University of Lodz, Stefanowskiego 1/15, 90-924 Lodz (Poland)

    2015-10-23

    We discuss the use of perpetual points for tracing the hidden and the rare attractors of dynamical systems. The analysis of perpetual points and their co-existence due to the parameters values is presented and the impact of these points on the behavior of the systems is shown. The results are obtained for single as well as coupled externally excited van der Pol–Duffing oscillators. The presented results can be generalized to other systems having different dynamics. - Highlights: • Computation of perpetual points in forced nonlinear dynamical systems. • Locating the hidden and rare attractors using perpetual points. • Analysis of states and different types of synchronization in coupled systems. • Understanding the complexity in coupled and uncoupled forced van der Pol–Duffing oscillator.

  16. Penta-Quark States with Strangeness, Hidden Charm and Beauty

    Science.gov (United States)

    Wu, Jia-Jun; Zou, Bing-Song

    The classical quenched quark models with three constituent quarks provide a good description for the baryon spatial ground states, but fail to reproduce the spectrum of baryon excited states. More and more evidences suggest that unquenched effects with multi-quark dynamics are necessary ingredients to solve the problem. Several new hyperon resonances reported recently could fit in the picture of penta-quark states. Based on this picture, some new hyperon excited states were predicted to exist; meanwhile with extension from strangeness to charm and beauty, super-heavy narrow N* and Λ* resonances with hidden charm or beauty were predicted to be around 4.3 and 11 GeV, respectively. Recently, two of such N* with hidden charm might have been observed by the LHCb experiment. More of those states are expected to be observed in near future. This opens a new window in order to study hadronic dynamics for the multi-quark states.

  17. Penta-quark States with Strangeness, Hidden Charm and Beauty

    CERN Document Server

    Wu, Jia-Jun

    2015-01-01

    The classical quenched quark models with three constituent quarks provide a good description for the baryon spatial ground states, but fail to reproduce the spectrum of baryon excited states. More and more evidences suggest that unquenched effects with multi-quark dynamics are necessary ingredients to solve the problem. Several new hyperon resonances reported recently could fit in the picture of penta-quark states. Based on this picture, some new hyperon excited states were predicted to exist; meanwhile with extension from strangeness to charm and beauty, super-heavy narrow $N^*$ and $\\Lambda^*$ resonances with hidden charm or beauty were predicted to be around 4.3 and 11 GeV, respectively. Recently, two of such $N^*$ with hidden charm might have been observed by the LHCb experiment. More of those states are expected to be observed in near future. This opens a new window in order to study hadronic dynamics for the multi-quark states.

  18. Markov chain Monte Carlo simulation for Bayesian Hidden Markov Models

    Science.gov (United States)

    Chan, Lay Guat; Ibrahim, Adriana Irawati Nur Binti

    2016-10-01

    A hidden Markov model (HMM) is a mixture model which has a Markov chain with finite states as its mixing distribution. HMMs have been applied to a variety of fields, such as speech and face recognitions. The main purpose of this study is to investigate the Bayesian approach to HMMs. Using this approach, we can simulate from the parameters' posterior distribution using some Markov chain Monte Carlo (MCMC) sampling methods. HMMs seem to be useful, but there are some limitations. Therefore, by using the Mixture of Dirichlet processes Hidden Markov Model (MDPHMM) based on Yau et. al (2011), we hope to overcome these limitations. We shall conduct a simulation study using MCMC methods to investigate the performance of this model.

  19. Wikipedia mining of hidden links between political leaders

    CERN Document Server

    Frahm, Klaus M; Shepelyansky, Dima L

    2016-01-01

    We describe a new method of reduced Google matrix which allows to establish direct and hidden links between a subset of nodes of a large directed network. This approach uses parallels with quantum scattering theory, developed for processes in nuclear and mesoscopic physics and quantum chaos. The method is applied to the Wikipedia networks in different language editions analyzing several groups of political leaders of USA, UK, Germany, France, Russia and G20. We demonstrate that this approach allows to recover reliably direct and hidden links among political leaders. We argue that the reduced Google matrix method can form the mathematical basis for studies in social and political sciences analyzing Leader-Members eXchange (LMX).

  20. Attribute-Based Encryption with Partially Hidden Ciphertext Policies

    Science.gov (United States)

    Nishide, Takashi; Yoneyama, Kazuki; Ohta, Kazuo

    We propose attribute-based encryption schemes where encryptor-specified policies (called ciphertext policies) are hidden. By using our schemes, an encryptor can encrypt data with a hidden access control policy. A decryptor obtains her secret key associated with her attributes from a trusted authority in advance and if the attributes associated with the decryptor's secret key do not satisfy the access control policy associated with the encrypted data, the decryptor cannot decrypt the data or guess even what access control policy was specified by the encryptor. We prove security of our construction based on the Decisional Bilinear Diffie-Hellman assumption and the Decision Linear assumption. In our security notion, even the legitimate decryptor cannot obtain the information about the access control policy associated with the encrypted data more than the fact that she can decrypt the data.

  1. Inhomogeneous spatial point processes with hidden second-order stationarity

    DEFF Research Database (Denmark)

    Hahn, Ute; Jensen, Eva B. Vedel

    correlation function g(u, v) is a function of u −˘ v, where −˘ is a generalized subtraction operator. For the reweighted second-order stationary processes, the subtraction operator is simply u −˘ v = u − v. The processes in the extended class are called hidden second-order stationary because, in many cases......Modelling of inhomogeneous spatial point patterns is a challenging research area with numerous applications in diverse areas of science. In recent years, the focus has mainly been on the class of reweighted second-order stationary point processes that is characterized by the mathematically...... attractive property of a translation invariant pair correlation function. Motivated by examples where this model class is not adequate, we extend the class of reweighted second-order stationary processes. The extended class consists of hidden second-order stationary point processes for which the pair...

  2. Generation and Analysis of Hidden Optical-Polarization States

    CERN Document Server

    Singh, Ravi S

    2010-01-01

    A hybrid Optical-Device (Phase-Conjugating Mirror Michelson Interferometer), made up of Phase-conjugate mirror along with ordinary mirror and Polarization Beam-splitter, is formally designed and investigated for the generation of an unusual Optical-Polarization States. This weird yet 'essentially single-mode' optical-polarization state has non-random 'ratio of amplitudes' and non-random 'sum of phases' in orthogonal bases-modes contrary to usual 'truly single-mode' optical-polarization states of which non-random 'ratio of amplitudes' and non-random 'difference of phases' serves as optical-polarization characteristic parameters. Since it is seen not to be characterized by Stokes parameters, one may, therefore, assign the name 'Hidden Optical-Polarization States (HOPS)'. HOPS are characterized by a set of parameters, namely, Hidden Optical-Polarization parameters. Formal experimental schemes are presented to experimentally measure these parameters and, thus, offering characterization of HOPS.

  3. Hidden Wounds? Inflammatory Links Between Childhood Trauma and Psychopathology.

    Science.gov (United States)

    Danese, Andrea; Baldwin, Jessie R

    2017-01-03

    Childhood trauma is a key risk factor for psychopathology. However, little is known about how exposure to childhood trauma is translated into biological risk for psychopathology. Observational human studies and experimental animal models suggest that childhood exposure to stress can trigger an enduring systemic inflammatory response not unlike the bodily response to physical injury. In turn, these "hidden wounds" of childhood trauma can affect brain development, key behavioral domains (e.g., cognition, positive valence systems, negative valence systems), reactivity to subsequent stressors, and, ultimately, risk for psychopathology. Further research is needed to better characterize the inflammatory links between childhood trauma and psychopathology. Detecting and healing these hidden wounds may help prevent and treat psychopathology emerging after childhood trauma.

  4. A Sequence of Relaxations Constraining Hidden Variable Models

    CERN Document Server

    Steeg, Greg Ver

    2011-01-01

    Many widely studied graphical models with latent variables lead to nontrivial constraints on the distribution of the observed variables. Inspired by the Bell inequalities in quantum mechanics, we refer to any linear inequality whose violation rules out some latent variable model as a "hidden variable test" for that model. Our main contribution is to introduce a sequence of relaxations which provides progressively tighter hidden variable tests. We demonstrate applicability to mixtures of sequences of i.i.d. variables, Bell inequalities, and homophily models in social networks. For the last, we demonstrate that our method provides a test that is able to rule out latent homophily as the sole explanation for correlations on a real social network that are known to be due to influence.

  5. Wikipedia mining of hidden links between political leaders

    Science.gov (United States)

    Frahm, Klaus M.; Jaffrès-Runser, Katia; Shepelyansky, Dima L.

    2016-12-01

    We describe a new method of reduced Google matrix which allows to establish direct and hidden links between a subset of nodes of a large directed network. This approach uses parallels with quantum scattering theory, developed for processes in nuclear and mesoscopic physics and quantum chaos. The method is applied to the Wikipedia networks in different language editions analyzing several groups of political leaders of USA, UK, Germany, France, Russia and G20. We demonstrate that this approach allows to recover reliably direct and hidden links among political leaders. We argue that the reduced Google matrix method can form the mathematical basis for studies in social and political sciences analyzing Leader-Members eXchange (LMX).

  6. HMMEditor: a visual editing tool for profile hidden Markov model

    Directory of Open Access Journals (Sweden)

    Cheng Jianlin

    2008-03-01

    Full Text Available Abstract Background Profile Hidden Markov Model (HMM is a powerful statistical model to represent a family of DNA, RNA, and protein sequences. Profile HMM has been widely used in bioinformatics research such as sequence alignment, gene structure prediction, motif identification, protein structure prediction, and biological database search. However, few comprehensive, visual editing tools for profile HMM are publicly available. Results We develop a visual editor for profile Hidden Markov Models (HMMEditor. HMMEditor can visualize the profile HMM architecture, transition probabilities, and emission probabilities. Moreover, it provides functions to edit and save HMM and parameters. Furthermore, HMMEditor allows users to align a sequence against the profile HMM and to visualize the corresponding Viterbi path. Conclusion HMMEditor provides a set of unique functions to visualize and edit a profile HMM. It is a useful tool for biological sequence analysis and modeling. Both HMMEditor software and web service are freely available.

  7. Perpetual points and hidden attractors in dynamical systems

    Science.gov (United States)

    Dudkowski, Dawid; Prasad, Awadhesh; Kapitaniak, Tomasz

    2015-10-01

    We discuss the use of perpetual points for tracing the hidden and the rare attractors of dynamical systems. The analysis of perpetual points and their co-existence due to the parameters values is presented and the impact of these points on the behavior of the systems is shown. The results are obtained for single as well as coupled externally excited van der Pol-Duffing oscillators. The presented results can be generalized to other systems having different dynamics.

  8. Uncovering Hidden Mathematics of the Multiplication Table Using Spreadsheets

    Directory of Open Access Journals (Sweden)

    Sergei Abramovich

    2007-05-01

    Full Text Available This paper reveals a number of learning activities emerging from a spreadsheetgenerated multiplication table. These activities are made possible by using such features of the software as conditional formatting, circular referencing, calculation through iteration, scroll bars, and graphing. The paper is a reflection on a mathematics content course designed for prospective elementary teachers using the hidden mathematics curriculum framework. It is written in support of standards for teaching and recommendations for teachers in North America.

  9. Blind Extraction and Security Analysis of Spread Spectrum Hidden Watermarks

    Science.gov (United States)

    2012-04-01

    DATES COVERED (From - To) JAN 2009 – DEC 2010 4. TITLE AND SUBTITLE BLIND EXTRACTION AND SECURITY ANALYSIS OF SPREAD SPECTRUM HIDDEN WATERMARKS ...Multi Signature Embedding, Watermarking , DSSS. 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT UU 18. NUMBER OF PAGES 15 19a... watermarks John A. Marsh*a,b, and Gerard F. Wohlrabc aSUNY Institute of Technology, 100 Seymour Dr., Utica, NY 13502; bAssured Information

  10. Hidden Markov Model Based Automated Fault Localization for Integration Testing

    OpenAIRE

    Ge, Ning; NAKAJIMA, SHIN; Pantel, Marc

    2013-01-01

    International audience; Integration testing is an expensive activity in software testing, especially for fault localization in complex systems. Model-based diagnosis (MBD) provides various benefits in terms of scalability and robustness. In this work, we propose a novel MBD approach for the automated fault localization in integration testing. Our method is based on Hidden Markov Model (HMM) which is an abstraction of system's component to simulate component's behaviour. The core of this metho...

  11. Information- Theoretic Analysis for the Difficulty of Extracting Hidden Information

    Institute of Scientific and Technical Information of China (English)

    ZHANG Wei-ming; LI Shi-qu; CAO Jia; LIU Jiu-fen

    2005-01-01

    The difficulty of extracting hidden information,which is essentially a kind of secrecy, is analyzed by information-theoretic method. The relations between key rate, message rate, hiding capacity and difficulty of extraction are studied in the terms of unicity distance of stego-key, and the theoretic conclusion is used to analyze the actual extracting attack on Least Significant Bit(LSB) steganographic algorithms.

  12. Abdominal candidiasis is a hidden reservoir of echinocandin resistance.

    Science.gov (United States)

    Shields, Ryan K; Nguyen, M Hong; Press, Ellen G; Clancy, Cornelius J

    2014-12-01

    FKS mutant Candida isolates were recovered from 24% (6/25) of abdominal candidiasis patients exposed to echinocandin. Candida glabrata (29%) and Candida albicans (14%) mutants were identified. Multidrug-resistant bacteria were recovered from 83% of FKS mutant infections. Mutations were associated with prolonged echinocandin exposure (P = 0.01), breakthrough infections (P = 0.03), and therapeutic failures despite source control interventions (100%). Abdominal candidiasis is a hidden reservoir for the emergence of echinocandin-resistant Candida.

  13. Drum Sound Detection in Polyphonic Music with Hidden Markov Models

    OpenAIRE

    Jouni Paulus; Anssi Klapuri

    2009-01-01

    This paper proposes a method for transcribing drums from polyphonic music using a network of connected hidden Markov models (HMMs). The task is to detect the temporal locations of unpitched percussive sounds (such as bass drum or hi-hat) and recognise the instruments played. Contrary to many earlier methods, a separate sound event segmentation is not done, but connected HMMs are used to perform the segmentation and recognition jointly. Two ways of using HMMs are studied: modelling combination...

  14. Consistent histories, quantum truth functionals, and hidden variables

    Science.gov (United States)

    Griffiths, Robert B.

    2000-01-01

    A central principle of consistent histories quantum theory, the requirement that quantum descriptions be based upon a single framework (or family), is employed to show that there is no conflict between consistent histories and a no-hidden-variables theorem of Bell, and Kochen and Specker, contrary to a recent claim by Bassi and Ghirardi. The argument makes use of `truth functionals' defined on a Boolean algebra of classical or quantum properties.

  15. Consistent histories, quantum truth functionals, and hidden variables

    CERN Document Server

    Griffiths, R B

    1999-01-01

    A central principle of consistent histories quantum theory, the requirement that quantum descriptions be based upon a single framework (or family), is employed to show that there is no conflict between consistent histories and a no-hidden-variables theorem of Bell, and Kochen and Specker, contrary to a recent claim by Bassi and Ghirardi. The argument makes use of ``truth functionals'' defined on a Boolean algebra of classical or quantum properties.

  16. Search for passing-through-walls neutrons constrains hidden braneworlds

    Directory of Open Access Journals (Sweden)

    Michaël Sarrazin

    2016-07-01

    Full Text Available In many theoretical frameworks our visible world is a 3-brane, embedded in a multidimensional bulk, possibly coexisting with hidden braneworlds. Some works have also shown that matter swapping between braneworlds can occur. Here we report the results of an experiment – at the Institut Laue-Langevin (Grenoble, France – designed to detect thermal neutron swapping to and from another braneworld, thus constraining the probability p2 of such an event. The limit, p87 in Planck length units.

  17. Physical nature of the hidden mass of the universe

    Energy Technology Data Exchange (ETDEWEB)

    Doroshkevich, A.G.; Khlopov, M.Y.

    1984-04-01

    Astronomical observational data on the large-scale structure of the Universe and on the distribution of hidden mass, interpreted within the framework of the adiabatic theory of galaxy formation, point to a dominance of weakly interacting particles with a mass in the range of 15--60 eV in the present Universe. Bounds are derived on the admissible admixtures of other relic particles.

  18. Stock Market Trend Analysis Using Hidden Markov Models

    OpenAIRE

    Kavitha, G.; Udhayakumar, A.; D. Nagarajan

    2013-01-01

    Price movements of stock market are not totally random. In fact, what drives the financial market and what pattern financial time series follows have long been the interest that attracts economists, mathematicians and most recently computer scientists [17]. This paper gives an idea about the trend analysis of stock market behaviour using Hidden Markov Model (HMM). The trend once followed over a particular period will sure repeat in future. The one day difference in close value of stocks for a...

  19. What are the Hidden Quantum Processes Behind Newton's Laws?

    OpenAIRE

    Ostoma, Tom; Trushyk, Mike

    1999-01-01

    We investigate the hidden quantum processes that are responsible for Newton's laws of motion and Newton's universal law of gravity. We apply Electro-Magnetic Quantum Gravity or EMQG to investigate Newtonian classical physics. EQMG is a quantum gravity theory that is manifestly compatible with Cellular Automata (CA) theory, a new paradigm for physical reality. EMQG is also based on a theory of inertia proposed by R. Haisch, A. Rueda, and H. Puthoff, which we modified and called Quantum Inertia...

  20. Hidden blazars and emission line variability of high redshift quasars

    Directory of Open Access Journals (Sweden)

    Feng Ma

    2001-01-01

    Full Text Available We have carried out a survey to search for hidden blazars in a sample of z 2 radio{loud quasars. The idea is based on our prediction that we should be able to see large C IV line variability not associated with observed continuum variations or most other emission lines in every radio{loud quasar. Here we report the initial results including the discovery of large C IV line variations in two quasars.

  1. Analysis of animal accelerometer data using hidden Markov models

    OpenAIRE

    2016-01-01

    Use of accelerometers is now widespread within animal biotelemetry as they provide a means of measuring an animal's activity in a meaningful and quantitative way where direct observation is not possible. In sequential acceleration data there is a natural dependence between observations of movement or behaviour, a fact that has been largely ignored in most analyses. Analyses of acceleration data where serial dependence has been explicitly modelled have largely relied on hidden Markov models (H...

  2. Hidden Markov models: the best models for forager movements?

    Directory of Open Access Journals (Sweden)

    Rocio Joo

    Full Text Available One major challenge in the emerging field of movement ecology is the inference of behavioural modes from movement patterns. This has been mainly addressed through Hidden Markov models (HMMs. We propose here to evaluate two sets of alternative and state-of-the-art modelling approaches. First, we consider hidden semi-Markov models (HSMMs. They may better represent the behavioural dynamics of foragers since they explicitly model the duration of the behavioural modes. Second, we consider discriminative models which state the inference of behavioural modes as a classification issue, and may take better advantage of multivariate and non linear combinations of movement pattern descriptors. For this work, we use a dataset of >200 trips from human foragers, Peruvian fishermen targeting anchovy. Their movements were recorded through a Vessel Monitoring System (∼1 record per hour, while their behavioural modes (fishing, searching and cruising were reported by on-board observers. We compare the efficiency of hidden Markov, hidden semi-Markov, and three discriminative models (random forests, artificial neural networks and support vector machines for inferring the fishermen behavioural modes, using a cross-validation procedure. HSMMs show the highest accuracy (80%, significantly outperforming HMMs and discriminative models. Simulations show that data with higher temporal resolution, HSMMs reach nearly 100% of accuracy. Our results demonstrate to what extent the sequential nature of movement is critical for accurately inferring behavioural modes from a trajectory and we strongly recommend the use of HSMMs for such purpose. In addition, this work opens perspectives on the use of hybrid HSMM-discriminative models, where a discriminative setting for the observation process of HSMMs could greatly improve inference performance.

  3. Search for passing-through-walls neutrons constrains hidden braneworlds

    Science.gov (United States)

    Sarrazin, Michaël; Pignol, Guillaume; Lamblin, Jacob; Pinon, Jonhathan; Méplan, Olivier; Terwagne, Guy; Debarsy, Paul-Louis; Petit, Fabrice; Nesvizhevsky, Valery V.

    2016-07-01

    In many theoretical frameworks our visible world is a 3-brane, embedded in a multidimensional bulk, possibly coexisting with hidden braneworlds. Some works have also shown that matter swapping between braneworlds can occur. Here we report the results of an experiment - at the Institut Laue-Langevin (Grenoble, France) - designed to detect thermal neutron swapping to and from another braneworld, thus constraining the probability p2 of such an event. The limit, p 87 in Planck length units.

  4. [Hidden allergens in processed food. The consumer perspective].

    Science.gov (United States)

    Schnadt, S

    2012-03-01

    Despite improved allergen-labeling and careful avoidance strategies, hidden allergens in food are a substantial risk for unintended reactions in food allergy sufferers. Unpublished data from a survey of the German Allergy and Asthma Association (Deutscher Allergie- und Asthmabund, DAAB) show that 85% of 738 questioned food allergic patients have experienced at least one allergic reaction from each prepacked products as well as food sold loose. Almost half of the participants said to have not received information of a food allergen as an ingredient or possible trace on the label. Different possibilities are discussed under which food allergens can be hidden in processed products, like incomprehensible labeling, labeling gaps, unexpected occurrence of allergens as well as cross contaminations or allergens in loose products. To each of the seven highlighted sources of hidden allergens in food, practical examples are given as well as proposals for the improvement of the situation from consumer view. The aim is to indicate possibilities and measures for politics and industry by which allergic consumers and their social circle are able to make an informed choice concerning the safe consumption of a certain product and to protect themselves from unintentional reactions.

  5. Grammatical-Restrained Hidden Conditional Random Fields for Bioinformatics applications

    Directory of Open Access Journals (Sweden)

    Martelli Pier

    2009-10-01

    Full Text Available Abstract Background Discriminative models are designed to naturally address classification tasks. However, some applications require the inclusion of grammar rules, and in these cases generative models, such as Hidden Markov Models (HMMs and Stochastic Grammars, are routinely applied. Results We introduce Grammatical-Restrained Hidden Conditional Random Fields (GRHCRFs as an extension of Hidden Conditional Random Fields (HCRFs. GRHCRFs while preserving the discriminative character of HCRFs, can assign labels in agreement with the production rules of a defined grammar. The main GRHCRF novelty is the possibility of including in HCRFs prior knowledge of the problem by means of a defined grammar. Our current implementation allows regular grammar rules. We test our GRHCRF on a typical biosequence labeling problem: the prediction of the topology of Prokaryotic outer-membrane proteins. Conclusion We show that in a typical biosequence labeling problem the GRHCRF performs better than CRF models of the same complexity, indicating that GRHCRFs can be useful tools for biosequence analysis applications. Availability GRHCRF software is available under GPLv3 licence at the website http://www.biocomp.unibo.it/~savojard/biocrf-0.9.tar.gz.

  6. Hidden charm octet tetraquarks from a diquark-antidiquark model

    CERN Document Server

    Zhu, Ruilin

    2016-01-01

    Four exotic charmonium-like states, i.e. $X(4140)$, $X(4274)$, $X(4500)$, and $X(4700)$, have been observed very recently by LHCb Collaboration in the decay process $B^+\\to J/\\psi \\phi K^+$ using the 3${\\rm fb}^{-1}$ data of $p\\bar p$ collision at $\\sqrt s= 7$ and $8$ TeV. In this paper, we investigate systematically the hidden charm tetraquark states. The hidden charm tetraquarks form an octet and a singlet representation according to flavor $SU(3)$ symmetry. Based on a diquark-antidiquark model, the hidden charm tetraquarks spectra are given. The previous XYZ exotic states altogether with the newly ones $X(4140)$, $X(4274)$, $X(4500)$, and $X(4700)$, can be well classified into certain representations. The spin-parities and masses of the XYZ are predicted, most of which are in agreement with the data. We particularly find that $Z_c(4430)$ can be treated as the first radial excitation of $Z_c(3900)$, while the $Y(1^{--})$ states can be obtained by the first orbital excitation of $X/Z$. Besides, we calculate ...

  7. Hidden symmetries of the Higgs oscillator and the conformal algebra

    Science.gov (United States)

    Evnin, Oleg; Nivesvivat, Rongvoram

    2017-01-01

    We give a solution to the long-standing problem of constructing the generators of hidden symmetries of the quantum Higgs oscillator, a particle on a d-sphere moving in a central potential varying as the inverse cosine-squared of the polar angle. This superintegrable system is known to possess a rich algebraic structure, including a hidden SU(d) symmetry that can be deduced from classical conserved quantities and degeneracies of the quantum spectrum. The quantum generators of this SU(d) have not been constructed thus far, except at d  =  2, and naive quantization of classical conserved quantities leads to deformed Lie algebras with quadratic terms in the commutation relations. The nonlocal generators we obtain here satisfy the standard su(d) Lie algebra, and their construction relies on a recently discovered realization of the conformal algebra, which contains a complete set of raising and lowering operators for the Higgs oscillator. This operator structure has emerged from a relation between the Higgs oscillator Schrödinger equation and the Klein-Gordon equation in Anti-de Sitter spacetime. From such a point-of-view, constructing the hidden symmetry generators reduces to manipulations within the abstract conformal algebra so(d, 2).

  8. Ontology-Based Automatically Hidden Web Portal Index

    Institute of Scientific and Technical Information of China (English)

    SONGHui; PANLeyun; MAFanyuan

    2004-01-01

    Many valuable databases on the Web have non-crawlable contents that are “hidden” behind the search forms. Information is available only by filling out HTML forms manually to query the underlying databases. For accessing data behind forms by automated agents, the critical task is having the corresponding query interfaces of the hidden databases that can be understood by machine. This paper presents an automatic approach of hidden Web portal index for various domains. It discovers and scrapes the query forms from Web pages based the tag-tree presentation, and then interpret them into the uniform mediate interfaces with the aid of domain ontology definition. To achieve high transformation accuracy, the domain ontology is also used to filter out the interfaces that are not related to the specific domain. The query interfaces gained finally represented with common concepts can automatically be indexed and retrieved by program. The experiments indicate that the algorithms used are efficient and the system is materially useful for information system or personalized Web search system to retrieval contents from hidden Web.

  9. In Brief: Hidden environment and health costs of energy

    Science.gov (United States)

    Showstack, Randy

    2009-10-01

    The hidden costs of energy production and use in the United States amounted to an estimated $120 billion in 2005, according to a 19 October report by the U.S. National Research Council. The report, “Hidden Costs of Energy: Unpriced Consequences of Energy Production and Use,” examines hidden costs, including the cost of air pollution damage to human health, which are not reflected in market prices of energy sources, electricity, or gasoline. The report found that in 2005, the total annual external damages from sulfur dioxide, nitrogen oxides, and particulate matter created by coal-burning power plants that produced 95% of the nation's coal-generated electricity were about $62 billion, with nonclimate damages averaging about 3.2 cents for every kilowatt-hour of energy produced. It is estimated that by 2030, nonclimate damages will fall to 1.7 cents per kilowatt-hour. The 2030 figure assumes that new policies already slated for implementation are put in place.

  10. On local-hidden-variable no-go theorems

    CERN Document Server

    Méthot, A A

    2005-01-01

    The strongest attack against quantum mechanics came in 1935 in the form of a paper by Einstein, Podolsky and Rosen. It was argued that the theory of quantum mechanics could not be called a complete theory of Nature, for every element of reality is not represented in the formalism as such. The authors then put forth a proposition: we must search for a theory where, upon knowing everything about the system, including possible hidden variables, one could make precise predictions concerning elements of reality. This project was ultimatly doomed in 1964 with the work of Bell Bell, who showed that the most general local hidden variable theory could not reproduce correlations that arise in quantum mechanics. There exist mainly three forms of no-go theorems for local hidden variable theories. Although almost every physicist knows the consequences of these no-go theorems, not every physicist is aware of the distinctions between the three or even their exact definitions. Thus we will discuss here the three principal fo...

  11. Cots Correlator Platform

    Science.gov (United States)

    Schaaf, Kjeld; Overeem, Ruud

    2004-06-01

    Moore’s law is best exploited by using consumer market hardware. In particular, the gaming industry pushes the limit of processor performance thus reducing the cost per raw flop even faster than Moore’s law predicts. Next to the cost benefits of Common-Of-The-Shelf (COTS) processing resources, there is a rapidly growing experience pool in cluster based processing. The typical Beowulf cluster of PC’s supercomputers are well known. Multiple examples exists of specialised cluster computers based on more advanced server nodes or even gaming stations. All these cluster machines build upon the same knowledge about cluster software management, scheduling, middleware libraries and mathematical libraries. In this study, we have integrated COTS processing resources and cluster nodes into a very high performance processing platform suitable for streaming data applications, in particular to implement a correlator. The required processing power for the correlator in modern radio telescopes is in the range of the larger supercomputers, which motivates the usage of supercomputer technology. Raw processing power is provided by graphical processors and is combined with an Infiniband host bus adapter with integrated data stream handling logic. With this processing platform a scalable correlator can be built with continuously growing processing power at consumer market prices.

  12. Single-molecule FRET reveals hidden complexity in a protein energy landscape.

    Science.gov (United States)

    Tsytlonok, Maksym; Ibrahim, Shehu M; Rowling, Pamela J E; Xu, Wenshu; Ruedas-Rama, Maria J; Orte, Angel; Klenerman, David; Itzhaki, Laura S

    2015-01-06

    Here, using single-molecule FRET, we reveal previously hidden conformations of the ankyrin-repeat domain of AnkyrinR, a giant adaptor molecule that anchors integral membrane proteins to the spectrin-actin cytoskeleton through simultaneous binding of multiple partner proteins. We show that the ankyrin repeats switch between high-FRET and low-FRET states, controlled by an unstructured "safety pin" or "staple" from the adjacent domain of AnkyrinR. Opening of the safety pin leads to unravelling of the ankyrin repeat stack, a process that will dramatically affect the relative orientations of AnkyrinR binding partners and, hence, the anchoring of the spectrin-actin cytoskeleton to the membrane. Ankyrin repeats are one of the most ubiquitous molecular recognition platforms in nature, and it is therefore important to understand how their structures are adapted for function. Our results point to a striking mechanism by which the order-disorder transition and, thereby, the activity of repeat proteins can be regulated.

  13. Communications payloads for geostationary platforms

    Science.gov (United States)

    Fordyce, S. W.

    1978-01-01

    Trends in communication satellites show increasing reuse of the frequency spectrum through multiple spot beams and orthogonal polarization, as well as consortia operation. Current reliance on orbital arc separation for frequency reuse may be inadequate for the projected traffic growth and the orbital slotting proposals before the ITU. This paper notes that cost advantages can accrue through common use of spacecraft subsystems and multiple users' platforms aboard a common geostationary platform. The rationale for such platforms is described and potential payloads are suggested.

  14. Utilizing platforms in industrialized construction

    DEFF Research Database (Denmark)

    Bonev, Martin; Wörösch, Michael; Hvam, Lars

    2015-01-01

    construction companies. A promising approach adapted by operations management and design theory regards individual building projects as the adjustment and recombination of components and processes from a set of predefined platforms, while configuration systems assure feasible building solutions. Design...... methods map structural platform characteristics so as to balance commonality and distinctiveness. Originality/value – This paper proposes a general theory of platform-based development and execution in the industrialised construction sector, which goes beyond concurrent approaches of standardising...

  15. Web Platform Application

    Energy Technology Data Exchange (ETDEWEB)

    Paulsworth, Ashley [Sunvestment Group, Frederick, MD (United States); Kurtz, Jim [Sunvestment Group, Frederick, MD (United States); Brun de Pontet, Stephanie [Sunvestment Group, Frederick, MD (United States)

    2016-06-15

    Sunvestment Energy Group (previously called Sunvestment Group) was established to create a web application that brings together site hosts, those who will obtain the energy from the solar array, with project developers and funders, including affinity investors. Sunvestment Energy Group (SEG) uses a community-based model that engages with investors who have some affinity with the site host organization. In addition to a financial return, these investors receive non-financial value from their investments and are therefore willing to offer lower cost capital. This enables the site host to enjoy more savings from solar through these less expensive Community Power Purchase Agreements (CPPAs). The purpose of this award was to develop an online platform to bring site hosts and investors together virtually.

  16. Energy Tracking Software Platform

    Energy Technology Data Exchange (ETDEWEB)

    Ryan Davis; Nathan Bird; Rebecca Birx; Hal Knowles

    2011-04-04

    Acceleration has created an interactive energy tracking and visualization platform that supports decreasing electric, water, and gas usage. Homeowners have access to tools that allow them to gauge their use and track progress toward a smaller energy footprint. Real estate agents have access to consumption data, allowing for sharing a comparison with potential home buyers. Home builders have the opportunity to compare their neighborhood's energy efficiency with competitors. Home energy raters have a tool for gauging the progress of their clients after efficiency changes. And, social groups are able to help encourage members to reduce their energy bills and help their environment. EnergyIT.com is the business umbrella for all energy tracking solutions and is designed to provide information about our energy tracking software and promote sales. CompareAndConserve.com (Gainesville-Green.com) helps homeowners conserve energy through education and competition. ToolsForTenants.com helps renters factor energy usage into their housing decisions.

  17. The Creative Soccer Platform

    DEFF Research Database (Denmark)

    Johan Torp Rasmussen, Ludvig; Østergaard, Lars Domino

    2016-01-01

    Creativity is essential in soccer due to the unpredictable and complex situations occurring in the game, where stereotypical play gradually loses its efficiency. Further, creativity is an important psychological factor for the development of soccer expertise, and valuing creativity increases...... satisfaction and well-being. Although creative players are highly desired by coaches, the subject of cultivating creativity is mostly ignored and traditional training settings may even hamper the players' creativity. The purpose of this article is to introduce a novel approach for enhancing soccer players......' creativity, The Creative Soccer Platform (TCSP), and to demonstrate the implications of applying it in youth soccer practice, by means of soccer-specific creativity exercises. TCSP encompasses four theoretically based didactic principles (task focus, parallel thinking, horizontal thinking, and no experienced...

  18. Power Quality Indices Estimation Platform

    Directory of Open Access Journals (Sweden)

    Eliana I. Arango-Zuluaga

    2013-11-01

    Full Text Available An interactive platform for estimating the quality indices in single phase electric power systems is presented. It meets the IEEE 1459-2010 standard recommendations. The platform was developed in order to support teaching and research activities in electric power quality. The platform estimates the power quality indices from voltage and current signals using three different algorithms based on fast Fourier transform (FFT, wavelet packet transform (WPT and least squares method. The results show that the algorithms implemented are efficient for estimating the quality indices of the power and the platform can be used according to the objectives established. 

  19. Flexible experimental FPGA based platform

    DEFF Research Database (Denmark)

    Andersen, Karsten Holm; Nymand, Morten

    2016-01-01

    This paper presents an experimental flexible Field Programmable Gate Array (FPGA) based platform for testing and verifying digital controlled dc-dc converters. The platform supports different types of control strategies, dc-dc converter topologies and switching frequencies. The controller platform...... interface supporting configuration and reading of setup parameters, controller status and the acquisition memory in a simple way. The FPGA based platform, provides an easy way within education or research to use different digital control strategies and different converter topologies controlled by an FPGA...

  20. Product Platform Screening at LEGO

    DEFF Research Database (Denmark)

    Mortensen, Niels Henrik; Steen Jensen, Thomas; Nielsen, Ole Fiil

    2012-01-01

    Product platforms offer great benefits to companies developing new products in highly competitive markets. Literature describes how a single platform can be designed from a technical point of view, but rarely mentions how the process begins. How do companies identify possible platform candidates...... after a few changes had been applied to the initial process layout. This case study shows how companies must focus on a limited selection of simultaneous projects in order to keep focus. Primary stakeholders must be involved from the very beginning, and short presentations of the platform concepts...

  1. Platform evolution studies

    Science.gov (United States)

    Walton, Barbara A.

    1990-01-01

    The polar orbiting platform (POP), being developed by the Work Package 3 (WP3) Project at the Goddard Space Flight Center, will play a key role in the NASA Leadership Initiative, Mission to Planet Earth (MPE). It becomes, with the addition of payloads, an Earth observation satellite observatory. Mission to Planet Earth also has geostationary platforms (GEOP) as part of its global observational system. A study was begun in March 1988 to assess the applicability of the POP orbital replacement units (ORUs) for a geostationary Earth observing mission. Two test cases, representative of MPE payloads, were studied. Case A was used to emphasize the GEOP configuration and design; it used a Titan/Centaur to achieve orbit. Case B, considered to be much further in the future, included some assembly at the Space Station Freedom manned base and use of an orbital transfer vehicle to achieve orbit; requirements on the manned base to support such a mission were emphasized. The study found the POP systems more than adequate to meet GEOP requirements. Two types of changes were required for the POP ORUs: (1) modification to use only one surface for heat rejection; for the battery ORU, this meant 'opening up' the ORU to retain the radiator area with a corresponding decrease in depth; and (2) deletion of equipment not needed. The Case A configuration was shown to be within the planned capability of the Titan IV/Centaur. Assembly requirements were included for the Case B configuration, which is driven by the large microwave antennas of two of the payloads. The final review was April 19, 1989.

  2. Scale invariant extension of the standard model with a strongly interacting hidden sector.

    Science.gov (United States)

    Hur, Taeil; Ko, P

    2011-04-08

    We present a scale invariant extension of the standard model with a new QCD-like strong interaction in the hidden sector. A scale Λ(H) is dynamically generated in the hidden sector by dimensional transmutation, and chiral symmetry breaking occurs in the hidden sector. This scale is transmitted to the SM sector by a real singlet scalar messenger S and can trigger electroweak symmetry breaking. Thus all the mass scales in this model arise from the hidden sector scale Λ(H), which has quantum mechanical origin. Furthermore, the lightest hadrons in the hidden sector are stable by the flavor conservation of the hidden sector strong interaction, and could be the cold dark matter (CDM). We study collider phenomenology, relic density, and direct detection rates of the CDM of this model.

  3. Platform Performance and Challenges - using Platforms in Lego Company

    DEFF Research Database (Denmark)

    Munk, Lone; Mortensen, Niels Henrik

    2009-01-01

    This article studies the performance and challenges of using nine implemented product platforms in LEGO Company. Most of these do produce results, but do not meet their goals due to challenges in their usage in the daily product. The main challenges are that the platforms are not being used...

  4. Clinical Trials

    Science.gov (United States)

    Clinical trials are research studies that test how well new medical approaches work in people. Each study answers ... prevent, screen for, diagnose, or treat a disease. Clinical trials may also compare a new treatment to a ...

  5. Analysis on hidden blood loss of total knee arthroplasty in treating knee osteoarthritis

    Institute of Scientific and Technical Information of China (English)

    SHEN Hui-liang; LI Zheng; FENG Ming-li; CAO Guang-le

    2011-01-01

    Background Total knee arthroplasty (TKA) is an important therapy for the treatment of various late-stage knee diseases. However, it has been observed that patients have lower hemoglobin (HB) counts postoperatively, which are significantly inconsistent with the measured blood loss. Although the concept of hidden blood loss has been presented in 2000, very little clinical attention has been paid since then. In this study, we investigated the characteristics and influential factor of hidden blood loss after TKA in treating knee osteoarthritis.Methods One hundred and eight patients, with 42 males and 66 females, were retrospectively analyzed. The perioperative blood loss and the hidden blood loss following TKA were calculated by Gross formula. Potential factors affecting perioperative and hidden blood loss included gender, surgical time, tourniquet time, hemostasis (during operation with deflating tourniquet), and reinfusion of salvaged blood.Results The average perioperative blood loss was found to be (1553±356) ml and the average hidden blood loss was (793±223) ml. The hidden blood loss of the male was significantly higher than that of the female, and was reduced by hemostasis during the operation with a deflating tourniquet. Hidden blood loss was not affected by postoperative blood salvage and reinfusion, surgical time, or tourniquet time.Conclusions When calculating the value of hidden blood loss by Gross formula, the lowest value of hematocrit should be chosen as the parameter so that hidden blood loss would not be underestimated. No significant differences could be found in hidden blood loss for males compared to females. Hidden blood loss can be reduced by hemostasis during operation with a deflating tourniquet. Although reinfusion of salvaged blood could not reduce the perioperative blood loss or hidden blood loss, it was still an effective method to reduce transfusion rate.

  6. Heterogeneous Web Data Extraction Algorithm Based On Modified Hidden Conditional Random Fields

    OpenAIRE

    Cui Cheng

    2014-01-01

    As it is of great importance to extract useful information from heterogeneous Web data, in this paper, we propose a novel heterogeneous Web data extraction algorithm using a modified hidden conditional random fields model. Considering the traditional linear chain based conditional random fields can not effectively solve the problem of complex and heterogeneous Web data extraction, we modify the standard hidden conditional random fields in three aspects, which are 1) Using the hidden Markov mo...

  7. Hidden Markov Model Application to Transfer The Trader Online Forex Brokers

    Directory of Open Access Journals (Sweden)

    Farida Suharleni

    2012-05-01

    Full Text Available Hidden Markov Model is elaboration of Markov chain, which is applicable to cases that can’t directly observe. In this research, Hidden Markov Model is used to know trader’s transition to broker forex online. In Hidden Markov Model, observed state is observable part and hidden state is hidden part. Hidden Markov Model allows modeling system that contains interrelated observed state and hidden state. As observed state in trader’s transition to broker forex online is category 1, category 2, category 3, category 4, category 5 by condition of every broker forex online, whereas as hidden state is broker forex online Marketiva, Masterforex, Instaforex, FBS and Others. First step on application of Hidden Markov Model in this research is making construction model by making a probability of transition matrix (A from every broker forex online. Next step is making a probability of observation matrix (B by making conditional probability of five categories, that is category 1, category 2, category 3, category 4, category 5 by condition of every broker forex online and also need to determine an initial state probability (π from every broker forex online. The last step is using Viterbi algorithm to find hidden state sequences that is broker forex online sequences which is the most possible based on model and observed state that is the five categories. Application of Hidden Markov Model is done by making program with Viterbi algorithm using Delphi 7.0 software with observed state based on simulation data. Example: By the number of observation T = 5 and observed state sequences O = (2,4,3,5,1 is found hidden state sequences which the most possible with observed state O as following : where X1 = FBS, X2 = Masterforex, X3 = Marketiva, X4 = Others, and X5 = Instaforex.

  8. Generation of Hidden Optical-Polarization: Squeezing and Non-Classicality

    OpenAIRE

    Gupta, Gyaneshwar K.; Kumar, Akhilesh; Singh, Ravi S

    2010-01-01

    A monochromatic double-mode coherent light endowed with orthogonally polarized photons propagating collinearly is studied in Degenerate Parametric Amplification. Generation of Hidden Optical- Polarized States is shown by non-zero values of Index of Hidden Optical-Polarization. Squeezing in HOPS is demonstrated by recognizing a Squeezing function. The Non-Classical feature of HOPS is observed by 'degree of Hidden Optical-Polarization' which attains non-classical value 'greater than unity'. The...

  9. Analysis of the first field trial

    OpenAIRE

    Mesa-Lao, Bartolomé; Carl, Michael

    2014-01-01

    In this work package, we evaluate the CASMACAT workbench in eld trials to study the use of the workbench in a real-world environment. We will also integrate the workbench into com- munity translation platforms and collect user activity data from both eld trials and volunteer translators. This Deliverable covers Tasks 6.1 and 6.2. Task 6.1: Field trials at translation agency. Three annual eld trials to evaluate the CASMACAT workbench in a real-world professional translatio...

  10. Mobile Learning Platform

    DEFF Research Database (Denmark)

    Annan, Nana Kofi; Ofori-Dwumfou, George; Falch, Morten

    2012-01-01

    This paper presents a study on a one year m-learning pilot project at Central University College in Ghana. This was done through a user trial, where the m-learning tool AD-CONNECT is introduced in 44 courses with a total of 500 students and 22 lecturers at the College. The paper reports on the fi......This paper presents a study on a one year m-learning pilot project at Central University College in Ghana. This was done through a user trial, where the m-learning tool AD-CONNECT is introduced in 44 courses with a total of 500 students and 22 lecturers at the College. The paper reports...... on the first experiences gained by both teachers and students by asking the following questions: What are the perceptions of teachers on m-learning? What are the effects of m-learning on students? What does m-learning contribute to face-to-face teaching and learning? Questionnaires were administered...... to students and lecturers to gather quantitative data on their views on the use of m-learning, particularly after using the AD-CONNECT M-Learning system. Also, observations and interviews were used to collect data from users which provided us with some qualitative data....

  11. Hidden Semi Markov Models for Multiple Observation Sequences: The mhsmm Package for R

    DEFF Research Database (Denmark)

    O'Connell, Jarad Michael; Højsgaard, Søren

    2011-01-01

    This paper describes the R package mhsmm which implements estimation and prediction methods for hidden Markov and semi-Markov models for multiple observation sequences. Such techniques are of interest when observed data is thought to be dependent on some unobserved (or hidden) state. Hidden Markov...... models only allow a geometrically distributed sojourn time in a given state, while hidden semi-Markov models extend this by allowing an arbitrary sojourn distribution. We demonstrate the software with simulation examples and an application involving the modelling of the ovarian cycle of dairy cows...

  12. To the point: reviews in medical education-taking control of the hidden curriculum.

    Science.gov (United States)

    Chuang, Alice W; Nuthalapaty, Francis S; Casey, Petra M; Kaczmarczyk, Joseph M; Cullimore, Amie J; Dalrymple, John L; Dugoff, Lorraine; Espey, Eve L; Hammoud, Maya M; Hueppchen, Nancy A; Katz, Nadine T; Peskin, Edward G

    2010-10-01

    This article, the ninth in the "To the Point" series that is prepared by the Association of Professors of Gynecology and Obstetrics Undergraduate Medical Education Committee, discusses the role of the "hidden curriculum" in shaping the professional identity of doctors in training. The characteristics that distinguish the formal curriculum and hidden curriculum are defined. Specific examples of hidden curricula in clinical environments and the positive and negative impacts that may result are highlighted. Techniques to evaluate clinical training environments and to identify the hidden curriculum are provided and are followed by methods to promote its positive messages and lessen its negative ones.

  13. Detection versus location judgments in a hidden pattern task: functional MRI and behavioral correlates.

    Science.gov (United States)

    Bolster, R Bruce; D'Arcy, Ryan C N; Song, Xiaowei; Runke, Dwayne S; Ryner, Lawrence

    2011-08-01

    We used functional magnetic resonance imaging (fMRI) to assess cortical involvement in a hidden pattern task. The experimental and control conditions involved judgment of the presence/absence versus the position of a complex pattern. Activation specific to hidden pattern identification was concentrated on frontal, dorsal parietal, and mesolimbic cortex. This was consistent not only across individual subjects, but with hidden figures tasks used in previous fMRI investigations. Results suggest that pattern identification relies on a relatively stable neural network controlling selective attention. In combination with fMRI, hidden pattern tasks may be useful in neuropsychological assessment of visual search and object identification.

  14. Placing Hidden Surface Removal within the CORE Graphics Standard: An Example.

    Science.gov (United States)

    1983-12-07

    index; coorcnt :- sidea ; new(Bptr); hidden :* Bptr; for i 1 to side a do (* transfer the point values *) with Bptre do begin hidden x_coor[i] :=x a[i...side-b + 1; x_a [ sidea ] : =-hidden_x coor[p2]; y_a[ sidea ] •= hiddenjY_coor [p2] ; z alside a] -= hiddenz_coor(p2]; w-a[side-a] := hidden.w_coor[p21...lists *) side a -= side a + 1; sideb := side b + 1; x a[side a] :::i-x intersection; x b[side b] : x intersection; y_--a[ sidea ] : y-intersection; y

  15. National Database for Clinical Trials Related to Mental Illness (NDCT)

    Data.gov (United States)

    U.S. Department of Health & Human Services — The National Database for Clinical Trials Related to Mental Illness (NDCT) is an extensible informatics platform for relevant data at all levels of biological and...

  16. Rationale and design of the Baptist Employee Healthy Heart Study: a randomized trial assessing the efficacy of the addition of an interactive, personalized, web-based, lifestyle intervention tool to an existing health information web platform in a high-risk employee population.

    Science.gov (United States)

    Post, Janisse M; Ali, Shozab S; Roberson, Lara L; Aneni, Ehimen C; Shaharyar, Sameer; Younus, Adnan; Jamal, Omar; Ahmad, Rameez; Aziz, Muhammad A; Malik, Rehan; Spatz, Erica S; Feldman, Theodore; Fialkow, Jonathan; Veledar, Emir; Cury, Ricardo C; Agatston, Arthur S; Nasir, Khurram

    2016-07-01

    Metabolic syndrome (MetS) and diabetes confer a high risk for developing subsequent cardiovascular disease (CVD). Persons with MetS constitute 24-34 % of the employee population at Baptist Health South Florida (BHSF), a self-insured healthcare organization. The Baptist Employee Healthy Heart Study (BEHHS) aims to assess the addition of a personalized, interactive, web-based, nutrition-management and lifestyle-management program to the existing health-expertise web platform available to BHSF employees in reducing and/or stabilizing CVD and lifestyle risk factors and markers of subclinical CVD. Subjects with MetS or Type II Diabetes will be recruited from an employee population at BHSF and randomized to either an intervention or a control arm. The intervention arm will be given access to a web-based personalized diet-modification and weight-modification program. The control arm will be reminded to use the standard informational health website available and accessible to all BHSF employees. Subjects will undergo coronary calcium testing, carotid intima-media thickness scans, peripheral arterial tonometry, and advanced lipid panel testing at visit 1, in addition to lifestyle and medical history questionnaires. All tests will be repeated at visits 2 and 4 with the exception of the coronary calcium test, which will only be performed at baseline and visit 4. Visit 3 will capture vitals, anthropometrics, and responses to the questionnaires only. Results of this study will provide information on the effectiveness of personalized, web-based, lifestyle-management tools in reducing healthcare costs, promoting healthy choices, and reducing cardiovascular risk in an employee population. It will also provide information about the natural history of carotid atherosclerosis and endothelial dysfunction in asymptomatic but high-risk populations. ClinicalTrials.gov registry, NCT01912209 . Registered on 3 July 2013.

  17. Rapid prototyping of robotic platforms

    CSIR Research Space (South Africa)

    De Ronde, Willis

    2016-11-01

    Full Text Available Building a robotic platform from raw materials can take anything from a few weeks to a few years to complete, depending on the complexity and size of the platform. This paper aims to introduce a novel approach of using abrasive waterjet machining...

  18. Preparing for a Product Platform

    DEFF Research Database (Denmark)

    Fiil-Nielsen, Ole; Munk, Lone; Mortensen, Niels Henrik

    2005-01-01

    they lead to increased sales due to more customized product as well as decreased costs due to reuse, making a product development platform a very profitable strategy for product developing companies. A successful implementation of a product development platform is not straightforward though...

  19. Finding an apprenticeship: hidden curriculum and social consequences.

    Science.gov (United States)

    Goastellec, Gaële; Ruiz, Guillaume

    2015-01-01

    In Switzerland, the majority of students are oriented toward professional training after compulsory schooling. At this stage, one of the biggest challenges for them is to find an apprenticeship position. Matching supply and demand is a complex process that not only excludes some students from having direct access to professional training but also forces them to make early choices regarding their future sector of employment. So, how does one find an apprenticeship? And what do the students' descriptions of their search for apprenticeships reveal about the institutional determinants of social inequalities at play in the system? Based on 29 interviews conducted in 2014 with 23 apprentices and 6 recruiters in the Canton of Vaud, this article interrogates how the dimensions of educational and social trajectories combine to affect access to apprenticeships and are accentuated by recruiters using a "hidden curriculum" during the recruitment process. A hidden curriculum consists of knowledge and skills not taught by the educational institution but which appear decisive in obtaining an apprenticeship. By analyzing the contrasting experiences of students in their search for an apprenticeship, we identify four types of trajectories that explain different types of school-to-apprenticeship transitions. We show how these determinants are reinforced by the "hidden curriculum" of recruitment based on the soft skills of feeling, autonomy, anticipation, and reflexivity that are assessed in the context of recruitment interactions. The discussion section debates how the criteria that appear to be used to identify the "right apprentice" tend to (re)produce inequalities between students. This not only depends on their academic results but also on their social and cultural skills, their ability to anticipate their choices and, more widely, their ability to be a subject in their recruitment search. "The Subject is neither the individual, nor the self, but the work through which an

  20. Geophysical Investigations at Hidden Dam, Raymond, California Flow Simulations

    Science.gov (United States)

    Minsley, Burke J.; Ikard, Scott

    2010-01-01

    Numerical flow modeling and analysis of observation-well data at Hidden Dam are carried out to supplement recent geophysical field investigations at the site (Minsley and others, 2010). This work also is complementary to earlier seepage-related studies at Hidden Dam documented by Cedergren (1980a, b). Known seepage areas on the northwest right abutment area of the downstream side of the dam was documented by Cedergren (1980a, b). Subsequent to the 1980 seepage study, a drainage blanket with a sub-drain system was installed to mitigate downstream seepage. Flow net analysis provided by Cedergren (1980a, b) suggests that the primary seepage mechanism involves flow through the dam foundation due to normal reservoir pool elevations, which results in upflow that intersects the ground surface in several areas on the downstream side of the dam. In addition to the reservoir pool elevations and downstream surface topography, flow is also controlled by the existing foundation geology as well as the presence or absence of a horizontal drain in the downstream portion of the dam. The current modeling study is aimed at quantifying how variability in dam and foundation hydrologic properties influences seepage as a function of reservoir stage. Flow modeling is implemented using the COMSOL Multiphysics software package, which solves the partially saturated flow equations in a two-dimensional (2D) cross-section of Hidden Dam that also incorporates true downstream topography. Use of the COMSOL software package provides a more quantitative approach than the flow net analysis by Cedergren (1980a, b), and allows for rapid evaluation of the influence of various parameters such as reservoir level, dam structure and geometry, and hydrogeologic properties of the dam and foundation materials. Historical observation-well data are used to help validate the flow simulations by comparing observed and predicted water levels for a range of reservoir elevations. The flow models are guided by, and

  1. Product Platform Screening at LEGO

    DEFF Research Database (Denmark)

    Mortensen, Niels Henrik; Steen Jensen, Thomas; Nielsen, Ole Fiil

    2012-01-01

    Product platforms offer great benefits to companies developing new products in highly competitive markets. Literature describes how a single platform can be designed from a technical point of view, but rarely mentions how the process begins. How do companies identify possible platform candidates......, and how do they assess if these candidates have enough potential to be worth implementing? Danish toy manufacturer LEGO has systematically gone through this process twice. The first time the results were poor; almost all platform candidates failed. The second time, though, has been largely successful...... after a few changes had been applied to the initial process layout. This case study shows how companies must focus on a limited selection of simultaneous projects in order to keep focus. Primary stakeholders must be involved from the very beginning, and short presentations of the platform concepts...

  2. ADAPTABLE ALTERNATE REALITY GAMES PLATFORM

    Directory of Open Access Journals (Sweden)

    Liviu-Adrian Cotfas

    2013-12-01

    Full Text Available In this paper, we present an alternate reality games platform that facilitates the creation of ARG projects with different themes and sizes. The platform is well integrated with the most important social media networks, thus facilitating both the involvement of the public and the creation of a more engaging interaction for the participants. A cloud-based architecture was used in order to allow the platform to easily accommodate projects of various sizes and to provide a good level of scalability. The platform is fully localizable in any language and multiple languages can be used at once to create projects that target users from different countries. An initial project that uses gamification to create an immersive learning environment has been created around the developed platform. The project combines professional and public feedback in order to provide an enhanced learning experience.

  3. New ALPS results on hidden-sector lightweights

    Energy Technology Data Exchange (ETDEWEB)

    Ehret, Klaus [Deutsches Elektronen-Synchrotron DESY, Notkestrasse 85, D-22607 Hamburg (Germany); Frede, Maik [Laser Zentrum Hannover e.V., Hollerithallee 8, D-30419 Hannover (Germany); Ghazaryan, Samvel [Deutsches Elektronen-Synchrotron DESY, Notkestrasse 85, D-22607 Hamburg (Germany); Hildebrandt, Matthias [Laser Zentrum Hannover e.V., Hollerithallee 8, D-30419 Hannover (Germany); Knabbe, Ernst-Axel [Deutsches Elektronen-Synchrotron DESY, Notkestrasse 85, D-22607 Hamburg (Germany); Kracht, Dietmar [Laser Zentrum Hannover e.V., Hollerithallee 8, D-30419 Hannover (Germany); Lindner, Axel, E-mail: axel.lindner@desy.d [Deutsches Elektronen-Synchrotron DESY, Notkestrasse 85, D-22607 Hamburg (Germany); List, Jenny [Deutsches Elektronen-Synchrotron DESY, Notkestrasse 85, D-22607 Hamburg (Germany); Meier, Tobias [Max-Planck-Institute for Gravitational Physics, Albert-Einstein-Institute, Institut fuer Gravitationsphysik, Leibniz Universitaet, Hannover, Callinstrasse 38, D-30167 Hannover (Germany); Meyer, Niels; Notz, Dieter; Redondo, Javier; Ringwald, Andreas [Deutsches Elektronen-Synchrotron DESY, Notkestrasse 85, D-22607 Hamburg (Germany); Wiedemann, Guenter [Hamburger Sternwarte, Gojenbergsweg 112, D-21029 Hamburg (Germany); Willke, Benno [Max-Planck-Institute for Gravitational Physics, Albert-Einstein-Institute, Institut fuer Gravitationsphysik, Leibniz Universitaet, Hannover, Callinstrasse 38, D-30167 Hannover (Germany)

    2010-05-31

    The ALPS Collaboration runs a 'Light Shining through a Wall' (LSW) experiment to search for photon oscillations into 'Weakly Interacting Sub-eV Particles' (WISPs) often predicted by extensions of the Standard Model. The experiment is set up around a superconducting HERA dipole magnet at the site of DESY. Due to several upgrades of the experiment we are able to place limits on the probability of photon-WISP-photon conversions of a fewx10{sup -25}. These limits result in today's most stringent laboratory constraints on the existence of low mass axion-like particles, hidden photons and minicharged particles.

  4. New ALPS Results on Hidden-Sector Lightweights

    CERN Document Server

    Ehret, Klaus; Ghazaryan, Samvel; Hildebrandt, Matthias; Knabbe, Ernst-Axel; Kracht, Dietmar; Lindner, Axel; List, Jenny; Meier, Tobias; Meyer, Niels; Notz, Dieter; Redondo, Javier; Ringwald, Andreas; Wiedemann, Günter; Willke, Benno

    2010-01-01

    The ALPS collaboration runs a "Light Shining through a Wall" (LSW) experiment to search for photon oscillations into "Weakly Interacting Sub-eV Particles" (WISPs) often predicted by extensions of the Standard Model. The experiment is set up around a superconducting HERA dipole magnet at the site of DESY. Due to several upgrades of the experiment we are able to place limits on the probability of photon-WISP-photon conversions of a few 10^{-25}. These limits result in today's most stringent laboratory constraints on the existence of low mass axion-like particles, hidden photons and minicharged particles.

  5. AIRWAY LABELING USING A HIDDEN MARKOV TREE MODEL

    Science.gov (United States)

    Ross, James C.; Díaz, Alejandro A.; Okajima, Yuka; Wassermann, Demian; Washko, George R.; Dy, Jennifer; San José Estépar, Raúl

    2014-01-01

    We present a novel airway labeling algorithm based on a Hidden Markov Tree Model (HMTM). We obtain a collection of discrete points along the segmented airway tree using particles sampling [1] and establish topology using Kruskal’s minimum spanning tree algorithm. Following this, our HMTM algorithm probabilistically assigns labels to each point. While alternative methods label airway branches out to the segmental level, we describe a general method and demonstrate its performance out to the subsubsegmental level (two generations further than previously published approaches). We present results on a collection of 25 computed tomography (CT) datasets taken from a Chronic Obstructive Pulmonary Disease (COPD) study. PMID:25436039

  6. The Research on Hidden Failures of Civil Aircraft

    Directory of Open Access Journals (Sweden)

    Lin Lie Shu

    2016-01-01

    Full Text Available The hidden failure is often appear on civil aircraft, and it is a big risk for normal safe operation. The reason for this failure is the instability of the resistance of the electrical contact. The study on electrical contact is applied science of the reliability, the contact resistance is an important parameter of the reliability of the electrical contact system. In this paper, It also Produces the latest research results from factors that affect contact resistance and contact resistance microscopic model, and then it produces the method of the calculating and measuring engineering about the contact resistance. Lastly, it is point out the future direction of the electrical contacts.

  7. Quantum hidden Markov models based on transition operation matrices

    Science.gov (United States)

    Cholewa, Michał; Gawron, Piotr; Głomb, Przemysław; Kurzyk, Dariusz

    2017-04-01

    In this work, we extend the idea of quantum Markov chains (Gudder in J Math Phys 49(7):072105 [3]) in order to propose quantum hidden Markov models (QHMMs). For that, we use the notions of transition operation matrices and vector states, which are an extension of classical stochastic matrices and probability distributions. Our main result is the Mealy QHMM formulation and proofs of algorithms needed for application of this model: Forward for general case and Vitterbi for a restricted class of QHMMs. We show the relations of the proposed model to other quantum HMM propositions and present an example of application.

  8. Inference with Constrained Hidden Markov Models in PRISM

    CERN Document Server

    Christiansen, Henning; Lassen, Ole Torp; Petit, Matthieu

    2010-01-01

    A Hidden Markov Model (HMM) is a common statistical model which is widely used for analysis of biological sequence data and other sequential phenomena. In the present paper we show how HMMs can be extended with side-constraints and present constraint solving techniques for efficient inference. Defining HMMs with side-constraints in Constraint Logic Programming have advantages in terms of more compact expression and pruning opportunities during inference. We present a PRISM-based framework for extending HMMs with side-constraints and show how well-known constraints such as cardinality and all different are integrated. We experimentally validate our approach on the biologically motivated problem of global pairwise alignment.

  9. Hidden Markov processes theory and applications to biology

    CERN Document Server

    Vidyasagar, M

    2014-01-01

    This book explores important aspects of Markov and hidden Markov processes and the applications of these ideas to various problems in computational biology. The book starts from first principles, so that no previous knowledge of probability is necessary. However, the work is rigorous and mathematical, making it useful to engineers and mathematicians, even those not interested in biological applications. A range of exercises is provided, including drills to familiarize the reader with concepts and more advanced problems that require deep thinking about the theory. Biological applications are t

  10. Learning Hidden Markov Models using Non-Negative Matrix Factorization

    CERN Document Server

    Cybenko, George

    2008-01-01

    The Baum-Welsh algorithm together with its derivatives and variations has been the main technique for learning Hidden Markov Models (HMM) from observational data. We present an HMM learning algorithm based on the non-negative matrix factorization (NMF) of higher order Markovian statistics that is structurally different from the Baum-Welsh and its associated approaches. The described algorithm supports estimation of the number of recurrent states of an HMM and iterates the non-negative matrix factorization (NMF) algorithm to improve the learned HMM parameters. Numerical examples are provided as well.

  11. Blocking Underhand Attacks by Hidden Coalitions (Extended Version)

    OpenAIRE

    Cristani, Matteo; Karafili, Erisa; Viganò, Luca

    2010-01-01

    Similar to what happens between humans in the real world, in open multi-agent systems distributed over the Internet, such as online social networks or wiki technologies, agents often form coalitions by agreeing to act as a whole in order to achieve certain common goals. However, agent coalitions are not always a desirable feature of a system, as malicious or corrupt agents may collaborate in order to subvert or attack the system. In this paper, we consider the problem of hidden coalitions, wh...

  12. Jim Shaw's The Hidden World as a Book of Poetry

    DEFF Research Database (Denmark)

    Sørensen, Bent

    documents, ’found’ in pulp publications, in thrift stores, on billboards, and on the Internet. These documents are mostly word-image hybrids, and their original functions may have been as commercials or advertisements, religious propaganda, doomsday prophecies, or other forms of naïve “didactic art...... a book of poetry. Drawing on genre theory, as well as recent work by, among others, Martin Glaz Serup and Thomas Hvid Kromann, I propose to read The Hidden World against its own grain, as it were, as a collection of conceptual poetry, participating in the discourses of belief and testimony....

  13. Desiring the Hidden God:Knowledge Without Belief

    OpenAIRE

    Perlmutter, Julian Felix

    2016-01-01

    For many people, the phenomenon of divine hiddenness is so total that it is far from clear to them that God (roughly speaking, the God of Jewish and Christian tradition) exists at all. Reasonably enough, they therefore do not believe that God exists. Yet it is possible, whilst lacking belief in God’s reality, nonetheless to see it as a possibility that is both realistic and attractive; and in this situation, one will likely want to be open to the considerable benefits that would be available ...

  14. Dark matter and dark forces from a supersymmetric hidden sector

    Energy Technology Data Exchange (ETDEWEB)

    Andreas, S.; Goodsell, M.D.; Ringwald, A.

    2011-09-15

    We show that supersymmetric ''Dark Force'' models with gravity mediation are viable. To this end, we analyse a simple supersymmetric hidden sector model that interacts with the visible sector via kinetic mixing of a light Abelian gauge boson with the hypercharge. We include all induced interactions with the visible sector such as neutralino mass mixing and the Higgs portal term. We perform a detailed parameter space scan comparing the produced dark matter relic abundance and direct detection cross-sections to current experiments. (orig.)

  15. A new `hidden colour hypothesis' in hadron physics

    Indian Academy of Sciences (India)

    Afsar Abbas

    2006-05-01

    A new `hidden colour hypothesis' within the framework of QCD, as an extension of and in keeping with the spirit of the `colour singlet hypothesis' is hereby proposed. As such it should play a role in a consistent description of exotic hadrons, such as diquonia, pentaquarks, dibaryons etc. How these exotic hadrons are affected by this new hypothesis is discussed here. This new hypothesis suggests that the experimentalists may not be looking for single exotics but for composites of two or more of the same.

  16. Hidden Markov Modeling for Weigh-In-Motion Estimation

    Energy Technology Data Exchange (ETDEWEB)

    Abercrombie, Robert K [ORNL; Ferragut, Erik M [ORNL; Boone, Shane [ORNL

    2012-01-01

    This paper describes a hidden Markov model to assist in the weight measurement error that arises from complex vehicle oscillations of a system of discrete masses. Present reduction of oscillations is by a smooth, flat, level approach and constant, slow speed in a straight line. The model uses this inherent variability to assist in determining the true total weight and individual axle weights of a vehicle. The weight distribution dynamics of a generic moving vehicle were simulated. The model estimation converged to within 1% of the true mass for simulated data. The computational demands of this method, while much greater than simple averages, took only seconds to run on a desktop computer.

  17. METHODOLOGY FOR DETECTION OF HIDDEN RESERVES OF ENTERPRISE INNOVATION POTENTIAL

    Directory of Open Access Journals (Sweden)

    R. I. Barmutsky

    2010-01-01

    Full Text Available Formation of an enterprise innovation potential requires investments of rather large financial resources, creation of offices and services which are involved in introduction and approbation of state-of-the-art technologies in production process and all these measures are not always properly repaid.Search for efficient production methods, introduction of new technologies which do not presuppose large expenses and intense personnel drawing-away from their direct functional duties are directed on detection and activation of hidden (unused innovation potential at an enterprise.

  18. Constraints on Light Hidden Sector Gauge Bosons from Supernova Cooling

    CERN Document Server

    Dent, James B; Krauss, Lawrence M

    2012-01-01

    We derive new bounds on hidden sector gauge bosons which could produce new energy loss mechanisms in supernovae, enlarging the excluded region in mass-coupling space by a significant factor compared to earlier estimates. Both considerations of trapping and possible decay of these particles need to be incorporated when determining such bounds, as does scattering on both neutrons and protons. For masses and couplings near the region which saturates current bounds, a significant background of such gauge bosons may also be produced due to the cumulative effects of all supernovae over cosmic history.

  19. Exhibiting eugenics: response and resistance to a hidden history.

    Science.gov (United States)

    Brave, Ralph; Sylva, Kathryn

    2007-01-01

    Human Plants, Human Harvest: The Hidden History of California Eugenics is the first-ever exhibition on the history of eugenics in California. The disappearance of this history for half a century, and the consequent absence of a "collective menory", were the primary factors determining the exhibit's sttrcture and content. Responses to the exhibit confirmed that most visitors "never knew" about this history. The exhibit is described in some detail, with selected imagery from the exhibit reproduced. After the initial exhibition, responses of other museums and foundation officials revealed a continuing resistance to this history being publicly displayed, though the sources of resistance varied.

  20. Frustration of total internal reflection by a hidden nanowire

    Science.gov (United States)

    Frumin, Leonid; Nemykin, Anton; Shapiro, David

    2016-12-01

    A metallic wire embedded in the dielectric substrate leads to frustration of the total internal reflection at the interface between dielectric and free space. The scattering by a gold cylinder is studied in order to exploit the light for hidden objects optical diagnostics. The p-wave incidenting by the angle close to total reflection with the frequency near plasmonic resonance is treated by the modified boundary elements method. The magnetic and electric fields at the interface are calculated. The scattering diagrams are found in near and far field.

  1. Diboson Resonance as a Portal to Hidden Strong Dynamics

    CERN Document Server

    Chiang, Cheng-Wei; Harigaya, Keisuke; Ibe, Masahiro; Yanagida, Tsutomu T

    2015-01-01

    We propose a new explanation for excess events observed in the search for a high-mass resonance decaying into dibosons by the ATLAS experiment. The resonance is identified as a composite spin-$0$ particle that couples to the Standard Model gauge bosons via dimension-5 operators. The excess events can be explained if the dimension-5 operators are suppressed by a mass scale of ${\\cal O}(1$--$10$) TeV. We also construct a model of hidden strong gauge dynamics which realizes the spin-$0$ particle as its lightest composite state, with appropriate couplings to Standard Model gauge bosons.

  2. Dealing with the Hidden Effects of Global Business Systems

    DEFF Research Database (Denmark)

    Slepniov, Dmitrij; Wæhrens, Brian Vejrum; Gubi, Ebbe

    2011-01-01

    companies may reduce this distance through reorganization and development of adequate global business systems solutions. The paper draws on a case study of a Danish industrial equipment firm. The paper describes and analyzes the company’s operations network configurations, which lay at the foundations...... of the company’s global business system. It is demonstrated how the operations configurations have been changing over time and affecting the overall business system. The paper identifies the key determinants and outcomes of this change and hidden effects of this change. Moreover, it proposes how the design...... of global business systems and improving the integration of such systems....

  3. Hidden variable models for quantum mechanics can have local parts

    CERN Document Server

    Larsson, Jan-Ake

    2009-01-01

    We present an explicit nonlocal nonsignaling model which has a nontrivial local part and is compatible with quantum mechanics. This model constitutes a counterexample to Colbeck and Renner's statement [Phys. Rev. Lett. 101, 050403 (2008)] that "any hidden variable model can only be compatible with quantum mechanics if its local part is trivial". Furthermore, we examine Colbeck and Renner's definition of "local part" and find that, in the case of models reproducing the quantum predictions for the singlet state, it is a restriction equivalent to the conjunction of nonsignaling and trivial local part.

  4. Revealing pentimenti: the hidden history in a painting

    Science.gov (United States)

    Gooch, Amy A.

    2007-02-01

    Art conservators often explore X-ray images of paintings to help find pentimenti, the artist's revisions hidden beneath the painting's visible first surfaces. X-ray interpretation is difficult due to artifacts in the image, superimposed features from all paint layers, and because image intensity depends on both the paint layer thickness and each pigment's opacity. We present a robust user-guided method to suppress clutter, find visually significant differences between X-ray images and color photographs, and visualize them together. These tools allow domain experts as well as museum visitors to explore the artist's creative decisions that led to a masterpiece.

  5. Inference in Hidden Markov Models with Explicit State Duration Distributions

    CERN Document Server

    Dewar, Michael; Wood, Frank

    2012-01-01

    In this letter we borrow from the inference techniques developed for unbounded state-cardinality (nonparametric) variants of the HMM and use them to develop a tuning-parameter free, black-box inference procedure for Explicit-state-duration hidden Markov models (EDHMM). EDHMMs are HMMs that have latent states consisting of both discrete state-indicator and discrete state-duration random variables. In contrast to the implicit geometric state duration distribution possessed by the standard HMM, EDHMMs allow the direct parameterisation and estimation of per-state duration distributions. As most duration distributions are defined over the positive integers, truncation or other approximations are usually required to perform EDHMM inference.

  6. Models with hidden regular variation: Generation and detection

    Directory of Open Access Journals (Sweden)

    Bikramjit Das

    2015-12-01

    Full Text Available We review the notions of multivariate regular variation (MRV and hidden regular variation (HRV for distributions of random vectors and then discuss methods for generating models exhibiting both properties concentrating on the non-negative orthant in dimension two. Furthermore we suggest diagnostic techniques that detect these properties in multivariate data and indicate when models exhibiting both MRV and HRV are plausible fits for the data. We illustrate our techniques on simulated data, as well as two real Internet data sets.

  7. Hidden Markov Model Based Visual Perception Filtering in Robotic Soccer

    Directory of Open Access Journals (Sweden)

    Can Kavaklioglu

    2009-02-01

    Full Text Available Autonomous robots can initiate their mission plans only after gathering sufficient information about the environment. Therefore reliable perception information plays a major role in the overall success of an autonomous robot. The Hidden Markov Model based post-perception filtering module proposed in this paper aims to identify and remove spurious perception information in a given perception sequence using the generic metapose definition. This method allows representing uncertainty in more abstract terms compared to the common physical representations. Our experiments with the four legged AIBO robot indicated that the proposed module improved perception and localization performance significantly.

  8. Everyday calculus discovering the hidden math all around us

    CERN Document Server

    Fernandez, Oscar E

    2014-01-01

    Calculus. For some of us, the word conjures up memories of ten-pound textbooks and visions of tedious abstract equations. And yet, in reality, calculus is fun, accessible, and surrounds us everywhere we go. In Everyday Calculus, Oscar Fernandez shows us how to see the math in our coffee, on the highway, and even in the night sky. Fernandez uses our everyday experiences to skillfully reveal the hidden calculus behind a typical day's events. He guides us through how math naturally emerges from simple observations-how hot coffee cools down, for example-and in discussions of over fifty familia

  9. Hidden attraction the history and mystery of magnetism

    CERN Document Server

    Verschuur, Gerrit L

    1993-01-01

    Long one of nature's most fascinating phenomena, magnetism was once the subject of many superstitions. Magnets were thought useful to thieves, effective as a love potion or as a cure for gout or spasms. They could remove sorcery from women and put demons to flight and even reconcile married couples. It was said that a lodestone pickled in the salt of sucking fish had the power to attract gold. Today, these beliefs have been put aside, but magnetism is no less remarkable for our modern understanding of it. In Hidden Attraction, Gerrit L. Verschuur, a noted astronomer and National Book Award nom

  10. Search for dark photons from supersymmetric hidden valleys.

    Science.gov (United States)

    Abazov, V M; Abbott, B; Abolins, M; Acharya, B S; Adams, M; Adams, T; Aguilo, E; Ahsan, M; Alexeev, G D; Alkhazov, G; Alton, A; Alverson, G; Alves, G A; Ancu, L S; Andeen, T; Anzelc, M S; Aoki, M; Arnoud, Y; Arov, M; Arthaud, M; Askew, A; Asman, B; Atramentov, O; Avila, C; BackusMayes, J; Badaud, F; Bagby, L; Baldin, B; Bandurin, D V; Banerjee, S; Barberis, E; Barfuss, A-F; Bargassa, P; Baringer, P; Barreto, J; Bartlett, J F; Bassler, U; Bauer, D; Beale, S; Bean, A; Begalli, M; Begel, M; Belanger-Champagne, C; Bellantoni, L; Bellavance, A; Benitez, J A; Beri, S B; Bernardi, G; Bernhard, R; Bertram, I; Besançon, M; Beuselinck, R; Bezzubov, V A; Bhat, P C; Bhatnagar, V; Blazey, G; Blessing, S; Bloom, K; Boehnlein, A; Boline, D; Bolton, T A; Boos, E E; Borissov, G; Bose, T; Brandt, A; Brock, R; Brooijmans, G; Bross, A; Brown, D; Bu, X B; Buchholz, D; Buehler, M; Buescher, V; Bunichev, V; Burdin, S; Burnett, T H; Buszello, C P; Calfayan, P; Calpas, B; Calvet, S; Cammin, J; Carrasco-Lizarraga, M A; Carrera, E; Carvalho, W; Casey, B C K; Castilla-Valdez, H; Chakrabarti, S; Chakraborty, D; Chan, K M; Chandra, A; Cheu, E; Cho, D K; Choi, S; Choudhary, B; Christoudias, T; Cihangir, S; Claes, D; Clutter, J; Cooke, M; Cooper, W E; Corcoran, M; Couderc, F; Cousinou, M-C; Crépé-Renaudin, S; Cuplov, V; Cutts, D; Cwiok, M; Das, A; Davies, G; De, K; de Jong, S J; De La Cruz-Burelo, E; DeVaughan, K; Déliot, F; Demarteau, M; Demina, R; Denisov, D; Denisov, S P; Desai, S; Diehl, H T; Diesburg, M; Dominguez, A; Dorland, T; Dubey, A; Dudko, L V; Duflot, L; Duggan, D; Duperrin, A; Dutt, S; Dyshkant, A; Eads, M; Edmunds, D; Ellison, J; Elvira, V D; Enari, Y; Eno, S; Ermolov, P; Escalier, M; Evans, H; Evdokimov, A; Evdokimov, V N; Facini, G; Ferapontov, A V; Ferbel, T; Fiedler, F; Filthaut, F; Fisher, W; Fisk, H E; Fortner, M; Fox, H; Fu, S; Fuess, S; Gadfort, T; Galea, C F; Garcia-Bellido, A; Gavrilov, V; Gay, P; Geist, W; Geng, W; Gerber, C E; Gershtein, Y; Gillberg, D; Ginther, G; Gómez, B; Goussiou, A; Grannis, P D; Greder, S; Greenlee, H; Greenwood, Z D; Gregores, E M; Grenier, G; Gris, Ph; Grivaz, J-F; Grohsjean, A; Grünendahl, S; Grünewald, M W; Guo, F; Guo, J; Gutierrez, G; Gutierrez, P; Haas, A; Hadley, N J; Haefner, P; Hagopian, S; Haley, J; Hall, I; Hall, R E; Han, L; Harder, K; Harel, A; Hauptman, J M; Hays, J; Hebbeker, T; Hedin, D; Hegeman, J G; Heinson, A P; Heintz, U; Hensel, C; Heredia-De La Cruz, I; Herner, K; Hesketh, G; Hildreth, M D; Hirosky, R; Hoang, T; Hobbs, J D; Hoeneisen, B; Hohlfeld, M; Hossain, S; Houben, P; Hu, Y; Hubacek, Z; Huske, N; Hynek, V; Iashvili, I; Illingworth, R; Ito, A S; Jabeen, S; Jaffré, M; Jain, S; Jakobs, K; Jamin, D; Jarvis, C; Jesik, R; Johns, K; Johnson, C; Johnson, M; Johnston, D; Jonckheere, A; Jonsson, P; Juste, A; Kajfasz, E; Karmanov, D; Kasper, P A; Katsanos, I; Kaushik, V; Kehoe, R; Kermiche, S; Khalatyan, N; Khanov, A; Kharchilava, A; Kharzheev, Y N; Khatidze, D; Kim, T J; Kirby, M H; Kirsch, M; Klima, B; Kohli, J M; Konrath, J-P; Kozelov, A V; Kraus, J; Kuhl, T; Kumar, A; Kupco, A; Kurca, T; Kuzmin, V A; Kvita, J; Lacroix, F; Lam, D; Lammers, S; Landsberg, G; Lebrun, P; Lee, W M; Leflat, A; Lellouch, J; Li, J; Li, L; Li, Q Z; Lietti, S M; Lim, J K; Lincoln, D; Linnemann, J; Lipaev, V V; Lipton, R; Liu, Y; Liu, Z; Lobodenko, A; Lokajicek, M; Love, P; Lubatti, H J; Luna-Garcia, R; Lyon, A L; Maciel, A K A; Mackin, D; Mättig, P; Magerkurth, A; Mal, P K; Malbouisson, H B; Malik, S; Malyshev, V L; Maravin, Y; Martin, B; McCarthy, R; McGivern, C L; Meijer, M M; Melnitchouk, A; Mendoza, L; Menezes, D; Mercadante, P G; Merkin, M; Merritt, K W; Meyer, A; Meyer, J; Mitrevski, J; Mommsen, R K; Mondal, N K; Moore, R W; Moulik, T; Muanza, G S; Mulhearn, M; Mundal, O; Mundim, L; Nagy, E; Naimuddin, M; Narain, M; Neal, H A; Negret, J P; Neustroev, P; Nilsen, H; Nogima, H; Novaes, S F; Nunnemann, T; Obrant, G; Ochando, C; Onoprienko, D; Orduna, J; Oshima, N; Osman, N; Osta, J; Otec, R; Otero y Garzón, G J; Owen, M; Padilla, M; Padley, P; Pangilinan, M; Parashar, N; Park, S-J; Park, S K; Parsons, J; Partridge, R; Parua, N; Patwa, A; Pawloski, G; Penning, B; Perfilov, M; Peters, K; Peters, Y; Pétroff, P; Piegaia, R; Piper, J; Pleier, M-A; Podesta-Lerma, P L M; Podstavkov, V M; Pogorelov, Y; Pol, M-E; Polozov, P; Popov, A V; Potter, C; Prado da Silva, W L; Protopopescu, S; Qian, J; Quadt, A; Quinn, B; Rakitine, A; Rangel, M S; Ranjan, K; Ratoff, P N; Renkel, P; Rich, P; Rijssenbeek, M; Ripp-Baudot, I; Rizatdinova, F; Robinson, S; Rodrigues, R F; Rominsky, M; Royon, C; Rubinov, P; Ruchti, R; Safronov, G; Sajot, G; Sánchez-Hernández, A; Sanders, M P; Sanghi, B; Savage, G; Sawyer, L; Scanlon, T; Schaile, D; Schamberger, R D; Scheglov, Y; Schellman, H; Schliephake, T; Schlobohm, S; Schwanenberger, C; Schwienhorst, R; Sekaric, J; Severini, H; Shabalina, E; Shamim, M; Shary, V; Shchukin, A A; Shivpuri, R K; Siccardi, V; Simak, V; Sirotenko, V; Skubic, P; Slattery, P; Smirnov, D; Snow, G R; Snow, J; Snyder, S; Söldner-Rembold, S; Sonnenschein, L; Sopczak, A; Sosebee, M; Soustruznik, K; Spurlock, B; Stark, J; Stolin, V; Stoyanova, D A; Strandberg, J; Strandberg, S; Strang, M A; Strauss, E; Strauss, M; Ströhmer, R; Strom, D; Stutte, L; Sumowidagdo, S; Svoisky, P; Takahashi, M; Tanasijczuk, A; Taylor, W; Tiller, B; Tissandier, F; Titov, M; Tokmenin, V V; Torchiani, I; Tsybychev, D; Tuchming, B; Tully, C; Tuts, P M; Unalan, R; Uvarov, L; Uvarov, S; Uzunyan, S; Vachon, B; van den Berg, P J; Van Kooten, R; van Leeuwen, W M; Varelas, N; Varnes, E W; Vasilyev, I A; Verdier, P; Vertogradov, L S; Verzocchi, M; Vilanova, D; Vint, P; Vokac, P; Voutilainen, M; Wagner, R; Wahl, H D; Wang, M H L S; Warchol, J; Watts, G; Wayne, M; Weber, G; Weber, M; Welty-Rieger, L; Wenger, A; Wetstein, M; White, A; Wicke, D; Williams, M R J; Wilson, G W; Wimpenny, S J; Wobisch, M; Wood, D R; Wyatt, T R; Xie, Y; Xu, C; Yacoob, S; Yamada, R; Yang, W-C; Yasuda, T; Yatsunenko, Y A; Ye, Z; Yin, H; Yip, K; Yoo, H D; Youn, S W; Yu, J; Zeitnitz, C; Zelitch, S; Zhao, T; Zhou, B; Zhu, J; Zielinski, M; Zieminska, D; Zivkovic, L; Zutshi, V; Zverev, E G

    2009-08-21

    We search for a new light gauge boson, a dark photon, with the D0 experiment. In the model we consider, supersymmetric partners are pair produced and cascade to the lightest neutralinos that can decay into the hidden sector state plus either a photon or a dark photon. The dark photon decays through its mixing with a photon into fermion pairs. We therefore investigate a previously unexplored final state that contains a photon, two spatially close leptons, and large missing transverse energy. We do not observe any evidence for dark photons and set a limit on their production.

  11. Hidden Markov Models for indirect classification of occupant behaviour

    DEFF Research Database (Denmark)

    Liisberg, Jon Anders Reichert; Møller, Jan Kloppenborg; Bloem, H.

    2016-01-01

    Even for similar residential buildings, a huge variability in the energy consumption can be observed. This variability is mainly due to the different behaviours of the occupants and this impacts the thermal (temperature setting, window opening, etc.) as well as the electrical (appliances, TV....... This paper focuses on the use of Hidden Markov Models (HMMs) to create methods for indirect observations and characterisation of occupant behaviour. By applying homogeneous HMMs on the electricity consumption of fourteen apartments, three states describing the data were found suitable. The most likely...

  12. Paper based electronics platform

    KAUST Repository

    Nassar, Joanna Mohammad

    2017-07-20

    A flexible and non-functionalized low cost paper-based electronic system platform fabricated from common paper, such as paper based sensors, and methods of producing paper based sensors, and methods of sensing using the paper based sensors are provided. A method of producing a paper based sensor can include the steps of: a) providing a conventional paper product to serve as a substrate for the sensor or as an active material for the sensor or both, the paper product not further treated or functionalized; and b) applying a sensing element to the paper substrate, the sensing element selected from the group consisting of a conductive material, the conductive material providing contacts and interconnects, sensitive material film that exhibits sensitivity to pH levels, a compressible and/or porous material disposed between a pair of opposed conductive elements, or a combination of two of more said sensing elements. The method of sensing can further include measuring, using the sensing element, a change in resistance, a change in voltage, a change in current, a change in capacitance, or a combination of any two or more thereof.

  13. Mobile Learning Platform

    DEFF Research Database (Denmark)

    Annan, Nana Kofi; Ofori-Dwumfou, George; Falch, Morten

    2012-01-01

    This paper presents a study on a one year m-learning pilot project at Central University College in Ghana. This was done through a user trial, where the m-learning tool AD-CONNECT is introduced in 44 courses with a total of 500 students and 22 lecturers at the College. The paper reports...... on the first experiences gained by both teachers and students by asking the following questions: What are the perceptions of teachers on m-learning? What are the effects of m-learning on students? What does m-learning contribute to face-to-face teaching and learning? Questionnaires were administered...... to students and lecturers to gather quantitative data on their views on the use of m-learning, particularly after using the AD-CONNECT M-Learning system. Also, observations and interviews were used to collect data from users which provided us with some qualitative data....

  14. Transactive Systems Simulation and Valuation Platform Trial Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Widergren, Steven E. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Hammerstrom, Donald J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Huang, Qiuhua [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Kalsi, Karanjit [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Lian, Jianming [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Makhmalbaf, Atefe [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); McDermott, Thomas E. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Sivaraman, Deepak [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Tang, Yingying [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Veeramany, Arun [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Woodward, James C. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2017-04-01

    Transactive energy systems use principles of value to coordinate responsive supply and demand in energy systems. Work continues within the Transactive Systems Program, which is funded by the U.S. Department of Energy at Pacific Northwest National Laboratory, to understand the value of, understand the theory behind, and simulate the behaviors of transactive energy systems. This report summarizes recent advances made by this program. The main capability advances include a more comprehensive valuation model, including recommended documentation that should make valuation studies of all sorts more transparent, definition of economic metrics with which transactive mechanisms can be evaluated, and multiple improvements to the time-simulation environment that is being used to evaluate transactive scenarios.

  15. Plat_Forms -- a contest: The web development platform comparison

    CERN Document Server

    Prechelt, Lutz

    2008-01-01

    "Plat_Forms" is a competition in which top-class teams of three programmers compete to implement the same requirements for a web-based system within 30 hours, each team using a different technology platform (Java EE, .NET, PHP, Perl, Python, or Ruby on Rails). The results will provide new insights into the real (rather than purported) pros, cons, and emergent properties of each platform. The evaluation will analyze many aspects of each solution, both external (usability, functionality, reliability, performance, etc.) and internal (structure, understandability, flexibility, etc.).

  16. 'Hidden' factors influencing quality of life in patients with multiple sclerosis.

    Science.gov (United States)

    Lysandropoulos, A P; Havrdova, E

    2015-10-01

    Traditional outcome measures for patients with multiple sclerosis (MS), whether in clinical trials or clinical practice, are currently in question. The combination of relapses, physical disability progression and magnetic resonance imaging (MRI) disease activity reflect only part of the impact that MS has on a patient's daily life. Quality of life (QoL) is considered by many to be the ideal outcome measure. Since it captures the patient's own perspective of well-being, QoL should be the primary focus when evaluating a patient and the main objective of MS management. Nevertheless, whilst numerous instruments to measure QoL in MS patients are available or proposed, there is no current consensus regarding which is the best tool to use and under what circumstances. QoL in patients with MS is determined by several factors beyond the more obvious; these include coping with the MS diagnosis, understanding the disease and the disease process, dealing with so-called 'hidden' symptoms such as fatigue, cognitive impairment and sexual disturbances, and managing the many associated personal challenges such as social isolation, family issues and working difficulties. Evidence is emerging that psychological interventions may be beneficial in MS patients although more research is required to confirm their utility. This article examines some factors that influence QoL in MS patients which may be overlooked in the general busyness of routine clinical practice. © 2015 The Author(s) European Journal of Neurology © 2015 EAN.

  17. Review of sampling hard-to-reach and hidden populations for HIV surveillance.

    Science.gov (United States)

    Magnani, Robert; Sabin, Keith; Saidel, Tobi; Heckathorn, Douglas

    2005-05-01

    Adequate surveillance of hard-to-reach and 'hidden' subpopulations is crucial to containing the HIV epidemic in low prevalence settings and in slowing the rate of transmission in high prevalence settings. For a variety of reasons, however, conventional facility and survey-based surveillance data collection strategies are ineffective for a number of key subpopulations, particularly those whose behaviors are illegal or illicit. This paper critically reviews alternative sampling strategies for undertaking behavioral or biological surveillance surveys of such groups. Non-probability sampling approaches such as facility-based sentinel surveillance and snowball sampling are the simplest to carry out, but are subject to a high risk of sampling/selection bias. Most of the probability sampling methods considered are limited in that they are adequate only under certain circumstances and for some groups. One relatively new method, respondent-driven sampling, an adaptation of chain-referral sampling, appears to be the most promising for general applications. However, as its applicability to HIV surveillance in resource-poor settings has yet to be established, further field trials are needed before a firm conclusion can be reached.

  18. Platform projections, compilers, interpreters and portability

    NARCIS (Netherlands)

    Bergstra, J.A.; Loots, M.E.

    1999-01-01

    Platform projection semantics extends projection semantics by means of the encapsulation of a processor used for program execution. Platform projection semantics abstracts from platform specific details. For a given program its platform projection semantics may be platform-independent. Two forms

  19. Current results and trends in platform switching

    Directory of Open Access Journals (Sweden)

    Hadi Salimi

    2011-01-01

    Full Text Available The platform switching (PLS concept was introduced in the literature in 2005. The biological benefits and clinical effectiveness of the PLS technique have been established by several studies. In this article different aspects of PLS concept are discussed. Crestal bone loss, biologic width, and stress distribution in this concept are comprehensively reviewed. In this article the relative published articles from 1990 to 2011 have been evaluated by electronic search. Because of controversial results especially in immediate loading and animal studies, further modified research is needed to establish the mechanism and effect of the PLS technique. Essential changes in studies including using the control group for accurate interpretation of results and long-term observation, particularly through, randomized, prospective, multicenter trials with large numbers of participants, and implants are necessary.

  20. Hidden Markov modeling of frequency-following responses to Mandarin lexical tones.

    Science.gov (United States)

    Llanos, Fernando; Xie, Zilong; Chandrasekaran, Bharath

    2017-08-12

    The frequency-following response (FFR) is a scalp-recorded electrophysiological potential reflecting phase-locked activity from neural ensembles in the auditory system. The FFR is often used to assess the robustness of subcortical pitch processing. Due to low signal-to-noise ratio at the single-trial level, FFRs are typically averaged across thousands of stimulus repetitions. Prior work using this approach has shown that subcortical encoding of linguistically-relevant pitch patterns is modulated by long-term language experience. We examine the extent to which a machine learning approach using hidden Markov modeling (HMM) can be utilized to decode Mandarin tone-categories from scalp-record electrophysiolgical activity. We then assess the extent to which the HMM can capture biologically-relevant effects (language experience-driven plasticity). To this end, we recorded FFRs to four Mandarin tones from 14 adult native speakers of Chinese and 14 of native English. We trained a HMM to decode tone categories from the FFRs with varying size of averages. Tone categories were decoded with above-chance accuracies using HMM. The HMM derived metric (decoding accuracy) revealed a robust effect of language experience, such that FFRs from native Chinese speakers yielded greater accuracies than native English speakers. Critically, the language experience-driven plasticity was captured with average sizes significantly smaller than those used in the extant literature. Our results demonstrate the feasibility of HMM in assessing the robustness of neural pitch. Machine-learning approaches can complement extant analytical methods that capture auditory function and could reduce the number of trials needed to capture biological phenomena. Copyright © 2017 Elsevier B.V. All rights reserved.