WorldWideScience

Sample records for hhs regulations apply

  1. 42 CFR 64.9 - Other HHS regulations that apply.

    Science.gov (United States)

    2010-10-01

    ..., TRAINING NATIONAL LIBRARY OF MEDICINE TRAINING GRANTS § 64.9 Other HHS regulations that apply. Several...) and requirements for drug-free workplace (grants). 45 CFR part 80—Nondiscrimination under programs...

  2. 45 CFR 91.18 - Age distinctions contained in HHS regulations.

    Science.gov (United States)

    2010-10-01

    ....18 Section 91.18 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION... distinctions contained in a rule or regulation issued by HHS shall be presumed to be necessary to the achievement of a statutory objective of the program or activity to which the rule or regulation applies...

  3. 48 CFR 301.603-72 - FAC-C and HHS SAC certification requirements.

    Science.gov (United States)

    2010-10-01

    ... HUMAN SERVICES GENERAL HHS ACQUISITION REGULATION SYSTEM Career Development, Contracting Authority, and... retention of certification, including the requirement to earn continuous learning points (CLPs). FAC-C... to employees for the first time at a department or agency.) (c) The FAC-C certification is based on...

  4. 77 FR 4034 - Annual Update of the HHS Poverty Guidelines

    Science.gov (United States)

    2012-01-26

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Office of the Secretary Annual Update of the HHS Poverty... update of the Department of Health and Human Services (HHS) poverty guidelines to account for last... program. For information about poverty figures for immigration forms, the Hill-Burton Uncompensated...

  5. 76 FR 3637 - Annual Update of the HHS Poverty Guidelines

    Science.gov (United States)

    2011-01-20

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Office of the Secretary Annual Update of the HHS Poverty... update of the Department of Health and Human Services (HHS) poverty guidelines to account for last... program. For information about poverty figures for immigration forms, the Hill-Burton Uncompensated...

  6. 78 FR 5182 - Annual Update of the HHS Poverty Guidelines

    Science.gov (United States)

    2013-01-24

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Office of the Secretary Annual Update of the HHS Poverty... update of the Department of Health and Human Services (HHS) poverty guidelines to account for last... program. For information about poverty figures for immigration forms, the Hill-Burton Uncompensated...

  7. 75 FR 3734 - 2009 HHS Poverty Guidelines Extended Until March 1, 2010

    Science.gov (United States)

    2010-01-22

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Office of the Secretary 2009 HHS Poverty Guidelines... 2009 Department of Health and Human Services (HHS) poverty guidelines will remain in effect until updated 2010 poverty guidelines are published, which shall not take place before March 1, 2010. DATES...

  8. 42 CFR 420.303 - HHS criteria for requesting books, documents, and records.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false HHS criteria for requesting books, documents, and... HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM PROGRAM INTEGRITY: MEDICARE Access to Books, Documents, and Records of Subcontractors § 420.303 HHS criteria for requesting books, documents, and records...

  9. 34 CFR 656.6 - What regulations apply?

    Science.gov (United States)

    2010-07-01

    ..., DEPARTMENT OF EDUCATION NATIONAL RESOURCE CENTERS PROGRAM FOR FOREIGN LANGUAGE AND AREA STUDIES OR FOREIGN LANGUAGE AND INTERNATIONAL STUDIES General § 656.6 What regulations apply? The following regulations apply... 34 Education 3 2010-07-01 2010-07-01 false What regulations apply? 656.6 Section 656.6 Education...

  10. 42 CFR 93.227 - Secretary or HHS.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Secretary or HHS. 93.227 Section 93.227 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH...

  11. 34 CFR 660.3 - What regulations apply?

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false What regulations apply? 660.3 Section 660.3 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION THE INTERNATIONAL RESEARCH AND STUDIES PROGRAM General § 660.3 What regulations apply...

  12. 42 CFR 73.3 - HHS select agents and toxins.

    Science.gov (United States)

    2010-10-01

    ... been genetically modified. (d) HHS select agents or toxins that meet any of the following criteria are... Recombinant Organisms: (1) Nucleic acids that can produce infectious forms of any of the select agent viruses...

  13. 42 CFR 59a.7 - Other HHS regulations that apply.

    Science.gov (United States)

    2010-10-01

    ... assistance through the Department of Health and Human Services—effectuation of title VI of the Civil Rights....7 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL LIBRARY OF MEDICINE GRANTS Grants for Establishing, Expanding, and Improving Basic Resources § 59a.7 Other...

  14. 42 CFR 52c.7 - Other HHS regulations that apply.

    Science.gov (United States)

    2010-10-01

    ... 401—Rights to inventions made by nonprofit organizations and small business firms under government... Effectuation of Title VI of the Civil Rights Act of 1964 45 CFR part 81—Practice and procedure for hearings... Animals,” Office for Protection from Research Risks, NIH (Revised September 1986), or successor [58 FR...

  15. 45 CFR 100.2 - What definitions apply to these regulations?

    Science.gov (United States)

    2010-10-01

    ... “Intergovernmental Review of Federal Programs.” Secretary means the Secretary of HHS or an official or employee of the Department acting for the Secretary under a delegation of authority. State means any of the 50...

  16. 34 CFR 350.4 - What regulations apply?

    Science.gov (United States)

    2010-07-01

    ... (IRB) reviews research that purposefully requires inclusion of children with disabilities or... REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION DISABILITY AND REHABILITATION RESEARCH PROJECTS AND CENTERS PROGRAM General § 350.4 What regulations apply? The following regulations apply to the Disability and...

  17. 34 CFR 400.3 - What other regulations apply to the Vocational and Applied Technology Education Programs?

    Science.gov (United States)

    2010-07-01

    ... Applied Technology Education Programs? 400.3 Section 400.3 Education Regulations of the Offices of the... VOCATIONAL AND APPLIED TECHNOLOGY EDUCATION PROGRAMS-GENERAL PROVISIONS § 400.3 What other regulations apply to the Vocational and Applied Technology Education Programs? The following regulations apply to the...

  18. The HHS-HCC Risk Adjustment Model for Individual and Small

    Data.gov (United States)

    U.S. Department of Health & Human Services — Volume 4, Issue 3 of the Medicare and Medicaid Research Review includes three articles describing the Department of Health and Human Services (HHS) developed risk...

  19. 24 CFR 232.620 - Determination of compliance by HHS.

    Science.gov (United States)

    2010-04-01

    ... HOUSING AND URBAN DEVELOPMENT MORTGAGE AND LOAN INSURANCE PROGRAMS UNDER NATIONAL HOUSING ACT AND OTHER AUTHORITIES MORTGAGE INSURANCE FOR NURSING HOMES, INTERMEDIATE CARE FACILITIES, BOARD AND CARE HOMES, AND... of Fire Safety Equipment Special Requirements § 232.620 Determination of compliance by HHS. An...

  20. 42 CFR 52.8 - Other HHS regulations and policies that apply.

    Science.gov (United States)

    2010-10-01

    ... (March 28, 1994)—NIH Guidelines on the Inclusion of Women and Minorities as Subjects in Clinical Research... on Women's Health, NIH, Room 201, Building 1, MSC 0161, BETHESDA, MD 20892-0161 (301-402-1770; not a...

  1. 42 CFR 63.10 - Other HHS regulations and policies that apply.

    Science.gov (United States)

    2010-10-01

    ... 14508 (March 28, 1994)—NIH Guidelines on the Inclusion of Women and Minorities as Subjects in Clinical Research. (Note: Interested persons should contact the Office of Research on Women's Health, NIH, Room 201...

  2. 78 FR 39730 - Privacy Act of 1974; CMS Computer Match No. 2013-11; HHS Computer Match No. 1302

    Science.gov (United States)

    2013-07-02

    ... 1974; CMS Computer Match No. 2013-11; HHS Computer Match No. 1302 AGENCY: Centers for Medicare & Medicaid Services (CMS), Department of Health and Human Services (HHS). ACTION: Notice of Computer Matching... notice announces the establishment of a CMP that CMS intends to conduct with State-based Administering...

  3. 76 FR 14669 - Privacy Act of 1974; CMS Computer Match No. 2011-02; HHS Computer Match No. 1007

    Science.gov (United States)

    2011-03-17

    ... 1974; CMS Computer Match No. 2011-02; HHS Computer Match No. 1007 AGENCY: Department of Health and Human Services (HHS), Centers for Medicare & Medicaid Services (CMS). ACTION: Notice of computer... notice establishes a computer matching agreement between CMS and the Department of Defense (DoD). We have...

  4. 42 CFR 55a.107 - What other regulations apply?

    Science.gov (United States)

    2010-10-01

    ... FOR BLACK LUNG CLINICS General Provisions § 55a.107 What other regulations apply? Other regulations which apply to the Black Lung Clinics Program include, but are not limited to, the following: 42 CFR...

  5. 78 FR 50419 - Privacy Act of 1974; CMS Computer Match No. 2013-10; HHS Computer Match No. 1310

    Science.gov (United States)

    2013-08-19

    ... 1974; CMS Computer Match No. 2013-10; HHS Computer Match No. 1310 AGENCY: Centers for Medicare & Medicaid Services (CMS), Department of Health and Human Services (HHS). ACTION: Notice of Computer Matching... notice announces the establishment of a CMP that CMS plans to conduct with the Department of Homeland...

  6. Optimization of the Fermentation Process of Actinomycete Strain Hhs.015T

    Directory of Open Access Journals (Sweden)

    Xinxuan Wang

    2010-01-01

    inoculation volume of 15.8%. The antimicrobial activity was increased by 20% by optimizing the environmental parameters. The results obtained allow an efficient production of components with antimicrobial activity by strain Hhs.015T on a large scale at low costs.

  7. 78 FR 73195 - Privacy Act of 1974: CMS Computer Matching Program Match No. 2013-01; HHS Computer Matching...

    Science.gov (United States)

    2013-12-05

    ... 1974: CMS Computer Matching Program Match No. 2013-01; HHS Computer Matching Program Match No. 1312 AGENCY: Centers for Medicare & Medicaid Services (CMS), Department of Health and Human Services (HHS... Privacy Act of 1974 (5 U.S.C. 552a), as amended, this notice announces the renewal of a CMP that CMS plans...

  8. 34 CFR 280.3 - What regulations apply to this program?

    Science.gov (United States)

    2010-07-01

    ... SECONDARY EDUCATION, DEPARTMENT OF EDUCATION MAGNET SCHOOLS ASSISTANCE PROGRAM General § 280.3 What regulations apply to this program? The following regulations apply to the Magnet Schools Assistance Program: (a) The Education Department General Administrative Regulations (EDGAR), 34 CFR parts 75 (Direct...

  9. 34 CFR 658.3 - What regulations apply?

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false What regulations apply? 658.3 Section 658.3 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION UNDERGRADUATE INTERNATIONAL STUDIES AND FOREIGN LANGUAGE PROGRAM General § 658.3 What...

  10. 34 CFR 461.4 - What regulations apply?

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false What regulations apply? 461.4 Section 461.4 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF VOCATIONAL AND ADULT EDUCATION, DEPARTMENT OF EDUCATION ADULT EDUCATION STATE-ADMINISTERED BASIC GRANT PROGRAM General § 461.4 What...

  11. 76 FR 20568 - HHS Plan for Retrospective Review Under Executive Order 13563

    Science.gov (United States)

    2011-04-13

    ... impact on a substantial number of small businesses as required by the Regulatory Flexibility Act; annual... technologies to facilitate greater participation in the rulemaking process, particularly social media and... actual impact? Public Participation--HHS solicits comments on ways to further engage and increase public...

  12. 20 CFR 30.318 - Can the FAB consider objections to HHS's reconstruction of a radiation dose or to the guidelines...

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Can the FAB consider objections to HHS's... OF 2000, AS AMENDED Adjudicatory Process Hearings and Final Decisions on Claims § 30.318 Can the FAB... to HHS's reconstruction of the radiation dose to which the employee was exposed, the FAB will...

  13. 42 CFR 52a.8 - Other HHS regulations and policies that apply.

    Science.gov (United States)

    2010-10-01

    ...—Effectuation of Title VI of the Civil Rights Act of 1964 45 CFR part 81—Practice and procedure for hearings... Laboratory Animals, Office of Laboratory Animal Welfare, Office of Extramural Research, NIH (Revised... Laboratory Animal Welfare, Office of Extramural Research, NIH, Rockledge 1, 6705 Rockledge Drive, Bethesda...

  14. 42 CFR 52e.8 - Other HHS regulations and policies that apply.

    Science.gov (United States)

    2010-10-01

    ...—Effectuation of Title VI of the Civil Rights Act of 1964 45 CFR part 81—Practice and procedure for hearings... Humane Care and Use of Laboratory Animals,” Office for Protection from Research Risks, NIH (Revised...

  15. 42 CFR 65a.11 - Other HHS regulations and policies that apply.

    Science.gov (United States)

    2010-10-01

    ... restrictions on lobbying 59 FR 14508 (March 28, 1994)—NIH Guidelines on the Inclusion of Women and Minorities... should contact the Office of Research on Women's Health, NIH, Room 201, Building 1, MSC 0161, Bethesda...

  16. 42 CFR 63a.11 - Other HHS regulations and policies that apply.

    Science.gov (United States)

    2010-10-01

    ... restrictions on lobbying 59 FR 14508 (March 28, 1994)—NIH Guidelines on the Inclusion of Women and Minorities... should contact the Office of Research on Women's Health, NIH, Room 201, Building 1, MSC 0161, Bethesda...

  17. 25 CFR 1000.220 - What regulations apply to self-governance Tribes?

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false What regulations apply to self-governance Tribes? 1000.220 Section 1000.220 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE...-DETERMINATION AND EDUCATION ACT Waiver of Regulations § 1000.220 What regulations apply to self-governance...

  18. 78 FR 42080 - Privacy Act of 1974; CMS Computer Match No. 2013-07; HHS Computer Match No. 1303; DoD-DMDC Match...

    Science.gov (United States)

    2013-07-15

    ... 1974; CMS Computer Match No. 2013-07; HHS Computer Match No. 1303; DoD-DMDC Match No. 18 AGENCY: Centers for Medicare & Medicaid Services (CMS), Department of Health and Human Services (HHS). ACTION... Act of 1974, as amended, this notice announces the establishment of a CMP that CMS plans to conduct...

  19. 78 FR 48169 - Privacy Act of 1974; CMS Computer Match No. 2013-02; HHS Computer Match No. 1306; DoD-DMDC Match...

    Science.gov (United States)

    2013-08-07

    ... 1974; CMS Computer Match No. 2013-02; HHS Computer Match No. 1306; DoD-DMDC Match No. 12 AGENCY: Department of Health and Human Services (HHS), Centers for Medicare & Medicaid Services (CMS). ACTION: Notice... of 1974, as amended, this notice establishes a CMP that CMS plans to conduct with the Department of...

  20. 45 CFR 46.101 - To what does this policy apply?

    Science.gov (United States)

    2010-10-01

    ..., such as (i) research on regular and special education instructional strategies, or (ii) research on the effectiveness of or the comparison among instructional techniques, curricula, or classroom management methods... SUBJECTS Basic HHS Policy for Protection of Human Research Subjects § 46.101 To what does this policy apply...

  1. 75 FR 45628 - Delayed Update of the HHS Poverty Guidelines for the Remainder of 2010

    Science.gov (United States)

    2010-08-03

    ..., Division of Facilities Compliance and Recovery, Health Resources and Services Administration, HHS, Room 10... reduction in eligibility for certain means-tested programs, including Medicaid, Supplemental Nutrition Assistance Program (SNAP), and child nutrition * * *.'' (Congressional Record (House), December 16, 2009, p...

  2. 45 CFR 660.2 - What definitions apply to these regulations?

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false What definitions apply to these regulations? 660.2 Section 660.2 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION INTERGOVERNMENTAL REVIEW OF THE NATIONAL SCIENCE FOUNDATION PROGRAMS AND ACTIVITIES § 660.2 What...

  3. A Novel Protein Elicitor BAR11 From Saccharothrix yanglingensis Hhs.015 Improves Plant Resistance to Pathogens and Interacts With Catalases as Targets

    OpenAIRE

    Yanan Zhang; Yanan Zhang; Xia Yan; Xia Yan; Hongmei Guo; Hongmei Guo; Feiyang Zhao; Feiyang Zhao; Lili Huang; Lili Huang

    2018-01-01

    Previously, we reported the biocontrol effects of Saccharothrix yanglingensis strain Hhs.015 on Valsa mali. Here, we report a novel protein elicitor BAR11 from the biocontrol strain Hhs.015 and its functions in plant defense responses. Functional analysis showed that the elicitor BAR11 significantly stimulated plant systemic resistance in Arabidopsis thaliana to Pseudomonas syringae pv. tomato DC3000. In addition, systemic tissues accumulated reactive oxygen species and deposited callose in a...

  4. 34 CFR 614.3 - What regulations apply to this program?

    Science.gov (United States)

    2010-07-01

    ... POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION PREPARING TOMORROW'S TEACHERS TO USE TECHNOLOGY § 614.3 What... Technology: (a) The Education Department General Administrative Regulations (EDGAR) as follows: (1) 34 CFR... 34 Education 3 2010-07-01 2010-07-01 false What regulations apply to this program? 614.3 Section...

  5. Updated Findings from the HHS Teen Pregnancy Prevention Evidence Review: January 2011 Through April 2013

    OpenAIRE

    Brian Goesling; Joanne Lee; Julieta Lugo-Gil; Timothy Novak

    2014-01-01

    Since 2009, the U.S. Department of Health and Human Services (HHS) has sponsored an ongoing systematic review of the teen pregnancy prevention research literature to help identify programs with evidence of effectiveness in reducing teen pregnancy, sexually transmitted infections (STIs), and associated sexual risk behaviors.

  6. Federal Research Opportunities: DOE, DOD, and HHS Need Better Guidance for Participant Activities

    Science.gov (United States)

    2016-01-01

    contract with DOE and the Economy Act of 1932, as amended. In addition, we examined documents developed by ORAU and used by DOE, DOD, and HHS to set forth...energy and climate change policy and analyses in the international economy , and building efficiencies. Environmental Protection Agency Climate...biomarkers for environmental contaminants. Federal Bureau of Investigation Juvenile prostitution and child abduction, causes of postmortem hair root

  7. Improving Community Stroke Preparedness in the HHS (Hip-Hop Stroke) Randomized Clinical Trial.

    Science.gov (United States)

    Williams, Olajide; Leighton-Herrmann Quinn, Ellyn; Teresi, Jeanne; Eimicke, Joseph P; Kong, Jian; Ogedegbe, Gbenga; Noble, James

    2018-04-01

    Deficiencies in stroke preparedness cause major delays to stroke thrombolysis, particularly among economically disadvantaged minorities. We evaluated the effectiveness of a stroke preparedness intervention delivered to preadolescent urban public school children on the stroke knowledge/preparedness of their parents. We recruited 3070 fourth through sixth graders and 1144 parents from 22 schools into a cluster randomized trial with schools randomized to the HHS (Hip-Hop Stroke) intervention or attentional control (nutrition classes). HHS is a 3-hour culturally tailored, theory-based, multimedia stroke literacy intervention targeting school children, which systematically empowers children to share stroke information with parents. Our main outcome measures were stroke knowledge/preparedness of children and parents using validated surrogates. Among children, it was estimated that 1% (95% confidence interval [CI], 0%-1%) of controls and 2% (95% CI, 1%-4%; P =0.09) of the intervention group demonstrated optimal stroke preparedness (perfect scores on the knowledge/preparedness test) at baseline, increasing to 57% (95% CI, 44%-69%) immediately after the program in the intervention group compared with 1% (95% CI, 0%-1%; P <0.001) among controls. At 3-month follow-up, 24% (95% CI, 15%-33%) of the intervention group retained optimal preparedness, compared with 2% (95% CI, 0%-3%; P <0.001) of controls. Only 3% (95% CI, 2%-4%) of parents in the intervention group could identify all 4 letters of the stroke FAST (Facial droop, Arm weakness, Speech disturbance, Time to call 911) acronym at baseline, increasing to 20% at immediate post-test (95% CI, 16%-24%) and 17% at 3-month delayed post-test (95% CI, 13%-21%; P =0.0062), with no significant changes (3% identification) among controls. Four children, all in the intervention group, called 911 for real-life stroke symptoms, in 1 case overruling a parent's wait-and-see approach. HHS is an effective, intergenerational model for

  8. 25 CFR 900.216 - What other statutes and regulations apply to contract disputes?

    Science.gov (United States)

    2010-04-01

    ... HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES CONTRACTS UNDER THE INDIAN SELF-DETERMINATION AND EDUCATION ASSISTANCE ACT Post-Award Contract Disputes § 900.216 What other statutes and regulations apply to... 25 Indians 2 2010-04-01 2010-04-01 false What other statutes and regulations apply to contract...

  9. Human regulator of telomere elongation helicase 1 (RTEL1) is required for the nuclear and cytoplasmic trafficking of pre-U2 RNA

    OpenAIRE

    Schertzer , Michael; Jouravleva , Karina; Perderiset , Mylène; Dingli , Florent; Loew , Damarys; Le Guen , Tangui; Bardoni , Barbara; De Villartay , Jean-Pierre; Revy , Patrick; Londono-Vallejo , Arturo

    2015-01-01

    International audience; Hoyeraal-Hreidarsson syndrome (HHS) is a severe form of Dyskeratosis congenita characterized by developmental defects, bone marrow failure and im-munodeficiency and has been associated with telom-ere dysfunction. Recently, mutations in Regulator of Telomere ELongation helicase 1 (RTEL1), a helicase first identified in Mus musculus as being responsible for the maintenance of long telomeres, have been identified in several HHS patients. Here we show that RTEL1 is require...

  10. 48 CFR 311.7001 - Section 508 accessibility standards for HHS Web site content and communications materials.

    Science.gov (United States)

    2010-10-01

    ..., documents, charts, posters, presentations (such as Microsoft PowerPoint), or video material that is specifically intended for publication on, or delivery via, an HHS-owned or -funded Web site, the Project... standards, and resolve any related issues. (c) Based on those discussions, the Project Officer shall provide...

  11. Human regulator of telomere elongation helicase 1 (RTEL1) is required for the nuclear and cytoplasmic trafficking of pre-U2 RNA.

    Science.gov (United States)

    Schertzer, Michael; Jouravleva, Karina; Perderiset, Mylene; Dingli, Florent; Loew, Damarys; Le Guen, Tangui; Bardoni, Barbara; de Villartay, Jean-Pierre; Revy, Patrick; Londoño-Vallejo, Arturo

    2015-02-18

    Hoyeraal-Hreidarsson syndrome (HHS) is a severe form of Dyskeratosis congenita characterized by developmental defects, bone marrow failure and immunodeficiency and has been associated with telomere dysfunction. Recently, mutations in Regulator of Telomere ELongation helicase 1 (RTEL1), a helicase first identified in Mus musculus as being responsible for the maintenance of long telomeres, have been identified in several HHS patients. Here we show that RTEL1 is required for the export and the correct cytoplasmic trafficking of the small nuclear (sn) RNA pre-U2, a component of the major spliceosome complex. RTEL1-HHS cells show abnormal subcellular partitioning of pre-U2, defects in the recycling of ribonucleotide proteins (RNP) in the cytoplasm and splicing defects. While most of these phenotypes can be suppressed by re-expressing the wild-type protein in RTEL1-HHS cells, expression of RTEL1 mutated variants in immortalized cells provokes cytoplasmic mislocalizations of pre-U2 and other RNP components, as well as splicing defects, thus phenocopying RTEL1-HHS cellular defects. Strikingly, expression of a cytoplasmic form of RTEL1 is sufficient to correct RNP mislocalizations both in RTEL1-HHS cells and in cells expressing nuclear mutated forms of RTEL1. This work unravels completely unanticipated roles for RTEL1 in RNP trafficking and strongly suggests that defects in RNP biogenesis pathways contribute to the pathology of HHS. © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

  12. 7 CFR 4285.93 - Other Federal statutes and regulations that apply.

    Science.gov (United States)

    2010-01-01

    ...—National Agricultural, Research, Extension, and Teaching Policy Act Amendments of 1981 if the project involves a college or university; (e) 7 CFR Part 3015—USDA Uniform Federal Assistance Regulations... Federal-State Research on Cooperatives Program § 4285.93 Other Federal statutes and regulations that apply...

  13. Resilience or hope? Incremental and convergent validity of the resilience scale for adults (RSA and the Herth hope scale (HHS in the prediction of anxiety and depression

    Directory of Open Access Journals (Sweden)

    Roxanna Morote

    2017-10-01

    Full Text Available Abstract Background Hope and resilience protect against inner vulnerabilities or harsh life circumstances; they explain individual differences in physical or mental health outcomes under high stress. They have been studied in complementary or competing theoretical frameworks; therefore, the study of measures of hope and resilience should be undertaken prior to explore if they are truly value-added for research. This study investigates the convergent and incremental validity of the Resilience Scale for Adults (RSA and the Herth Hope Scale (HHS, in the prediction of anxiety and depression (HSCL-25. Methods Participants in this community-based sample are 762 adults from 18 to 74 years old. They answered the RSA, HHS, Spanish Language Stressful Life-Events Checklist (SL-SLE, and the Hopkins Symptom Checklist-25 (HSCL-25. Incremental validity analyses combined hierarchical regression and structural equation models (SEM. First, hierarchical regression models were compared based on three criteria (R 2 Diff., ΔF, and semi-partial r, then the direct effect of resilience on affective symptoms was compared with the mediated effect of resilience on affective symptoms through hope. Results The hierarchical models showed that (1 hope and resilience account significantly for the variance of affective symptoms above age, sex, and life-stress; (2 Resilience Total score has greater incremental validity than positive scales of HHS Hope; and (3 RSA Total score, HHS Optimism/Spiritual support, Stressful life-events and sex are unique predictors of affective symptoms. The SEM analyses verified a stronger direct effect of resilience in the prediction of affective symptoms above the significant partial mediated effect of resilience through hope. Additionally, results show that age and better educational opportunities were associated with protection (i.e. resilience and hope and emotional well-being (i.e. affective symptoms and hopelessness. Women showed higher scores

  14. Resilience or hope? Incremental and convergent validity of the resilience scale for adults (RSA) and the Herth hope scale (HHS) in the prediction of anxiety and depression.

    Science.gov (United States)

    Morote, Roxanna; Hjemdal, Odin; Krysinska, Karolina; Martinez Uribe, Patricia; Corveleyn, Jozef

    2017-10-27

    Hope and resilience protect against inner vulnerabilities or harsh life circumstances; they explain individual differences in physical or mental health outcomes under high stress. They have been studied in complementary or competing theoretical frameworks; therefore, the study of measures of hope and resilience should be undertaken prior to explore if they are truly value-added for research. This study investigates the convergent and incremental validity of the Resilience Scale for Adults (RSA) and the Herth Hope Scale (HHS), in the prediction of anxiety and depression (HSCL-25). Participants in this community-based sample are 762 adults from 18 to 74 years old. They answered the RSA, HHS, Spanish Language Stressful Life-Events Checklist (SL-SLE), and the Hopkins Symptom Checklist-25 (HSCL-25). Incremental validity analyses combined hierarchical regression and structural equation models (SEM). First, hierarchical regression models were compared based on three criteria (R 2 Diff., ΔF, and semi-partial r), then the direct effect of resilience on affective symptoms was compared with the mediated effect of resilience on affective symptoms through hope. The hierarchical models showed that (1) hope and resilience account significantly for the variance of affective symptoms above age, sex, and life-stress; (2) Resilience Total score has greater incremental validity than positive scales of HHS Hope; and (3) RSA Total score, HHS Optimism/Spiritual support, Stressful life-events and sex are unique predictors of affective symptoms. The SEM analyses verified a stronger direct effect of resilience in the prediction of affective symptoms above the significant partial mediated effect of resilience through hope. Additionally, results show that age and better educational opportunities were associated with protection (i.e. resilience and hope) and emotional well-being (i.e. affective symptoms and hopelessness). Women showed higher scores in social competences and resources (RSA

  15. 75 FR 59722 - Agency Information Collection Activities; Submission for Office of Management and Budget Review...

    Science.gov (United States)

    2010-09-28

    ... Center for Food Safety and Applied Nutrition AGENCY: Food and Drug Administration, HHS. ACTION: Notice... Environmental Assessment for Submission to the Center for Food Safety and Applied Nutrition (OMB Control Number...-regulated articles. FDA also has eliminated the previously required Environmental Assessment (EA) and...

  16. 78 FR 78973 - Agency Information Collection Activities; Submission for Office of Management and Budget Review...

    Science.gov (United States)

    2013-12-27

    ... Center for Food Safety and Applied Nutrition AGENCY: Food and Drug Administration, HHS. ACTION: Notice... Environmental Assessment for Submission to the Center for Food Safety and Applied Nutrition (OMB Control Number... production of our regulated articles. We also have eliminated the previously required Environmental...

  17. 76 FR 46621 - Group Health Plans and Health Insurance Issuers Relating to Coverage of Preventive Services Under...

    Science.gov (United States)

    2011-08-03

    ... to the interim final regulations implementing the rules for group health plans and health insurance... dates. These interim final regulations generally apply to group health plans and group health insurance... from HHS on private health insurance for consumers can be found on the Centers for Medicare & Medicaid...

  18. 34 CFR 356.3 - What regulations apply to this program?

    Science.gov (United States)

    2010-07-01

    ... SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION DISABILITY AND REHABILITATION... purposefully requires inclusion of children with disabilities or individuals with mental disabilities as... 34 Education 2 2010-07-01 2010-07-01 false What regulations apply to this program? 356.3 Section...

  19. Seven words you can never say at HHS

    Directory of Open Access Journals (Sweden)

    Robbins RA

    2017-12-01

    Full Text Available No abstract available. Article truncated at 150 words. The recent announcement of the seven words you can never say at Health & Human Services (HHS reminded me of the late George Carlin’s routine, “Seven Words You Can Never Say on Television” (1. Policy analysts at the Centers for Disease Control (CDC in Atlanta were told of the list of forbidden words at a meeting last Thursday, December 14, with senior CDC officials who oversee the budget, according to an analyst who took part in the 90-minute briefing (2. The forbidden words are "vulnerable," "entitlement," "diversity," "transgender," "fetus," "evidence-based" and "science-based." In some instances, the analysts were given alternative phrases. Instead of “science-based” or “evidence-based,” the suggested phrase is “CDC bases its recommendations on science in consideration with community standards and wishes,” the person said. In other cases, no replacement words were immediately offered. This is the latest attempt by government departments to distort fact. As an example, the …

  20. 34 CFR 637.3 - What regulations apply to the Minority Science and Engineering Improvement Program?

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false What regulations apply to the Minority Science and... Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION MINORITY SCIENCE AND ENGINEERING IMPROVEMENT PROGRAM General § 637.3 What regulations apply to the Minority Science and Engineering...

  1. 45 CFR 1351.18 - What criteria has HHS established for deciding which Runaway and Homeless Youth Program grant...

    Science.gov (United States)

    2010-10-01

    ... which Runaway and Homeless Youth Program grant applications to fund? 1351.18 Section 1351.18 Public... SERVICES BUREAU RUNAWAY AND HOMELESS YOUTH PROGRAM Runaway and Homeless Youth Program Grant § 1351.18 What criteria has HHS established for deciding which Runaway and Homeless Youth Program grant applications to...

  2. Agriculture: Laws and Regulations that Apply to Your Agricultural Operation by Farm Activity

    Science.gov (United States)

    A general description of EPA’s requirements applicable to agriculture, and should only be used as a guide. Since rules and regulations may change use this information is a starting place to determine which regulations apply to your agricultural operation.

  3. Framework for applying probabilistic safety analysis in nuclear regulation

    International Nuclear Information System (INIS)

    Dimitrijevic, V.B.

    1997-01-01

    The traditional regulatory framework has served well to assure the protection of public health and safety. It has been recognized, however, that in a few circumstances, this deterministic framework has lead to an extensive expenditure on matters hat have little to do with the safe and reliable operation of the plant. Developments of plant-specific PSA have offered a new and powerful analytical tool in the evaluation of the safety of the plant. Using PSA insights as an aid to decision making in the regulatory process is now known as 'risk-based' or 'risk-informed' regulation. Numerous activities in the U.S. nuclear industry are focusing on applying this new approach to modify regulatory requirements. In addition, other approaches to regulations are in the developmental phase and are being evaluated. One is based on the performance monitoring and results and it is known as performance-based regulation. The other, called the blended approach, combines traditional deterministic principles with PSA insights and performance results. (author)

  4. 42 CFR 9.13 - Other federal laws, regulations, and statutes that apply to the sanctuary.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Other federal laws, regulations, and statutes that apply to the sanctuary. 9.13 Section 9.13 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND... SANCTUARY SYSTEM § 9.13 Other federal laws, regulations, and statutes that apply to the sanctuary. (a...

  5. 75 FR 57958 - Solicitation of Written Comments on Draft Tier 2 Strategies/Modules for Inclusion in the “HHS...

    Science.gov (United States)

    2010-09-23

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Solicitation of Written Comments on Draft Tier 2 Strategies/ Modules for Inclusion in the ``HHS Action Plan to Prevent Healthcare- Associated Infections'' AGENCY: Department of Health and Human Services, Office of the Assistant Secretary for Health, Office of...

  6. [Rules and regulations applying to incidents in radiotherapy].

    Science.gov (United States)

    Lohr, F; Baus, W; Vorwerk, H; Schlömp, B; André, L; Georg, D; Hodapp, N

    2012-07-01

    Radiotherapy is an essential and reliable element of the treatment armamentarium in oncology. Numerous rules, regulations, and protocols minimize the associated risks. It can, however, never be excluded that errors in the treatment delivery chain result in inadequate tumor doses or unnecessary damage to organs at risk. A legal framework governs the management of such incidents. The most important European and North American regulations are reported. Various directives issued by the European Union are differently implemented nationally. This applies particularly to the characterization of incidents that must be reported to authorities. Reporting thresholds, audit systems, and the extent of the integration of voluntary reporting systems vary. Radiotherapy incidents are dealt with differently on an international level. Changes are to be expected based on the European Basic Safety Standards Directive that is currently being prepared and will have to be implemented nationally in due course.

  7. Rules and regulations applying to incidents in radiotheraphy

    International Nuclear Information System (INIS)

    Lohr, F.; Andre, L.; Georg, D.; Hodapp, N.

    2012-01-01

    Aims and purpose: Radiotherapy is an essential and reliable element of the treatment armamentarium in oncology. Numerous rules, regulations, and protocols minimize the associated risks. It can, however, never be excluded that errors in the treatment delivery chain result in inadequate tumor doses or unnecessary damage to organs at risk. A legal framework governs the management of such incidents. The most important European and North American regulations are reported. Results: Various directives issued by the European Union are differently implemented nationally. This applies particularly to the characterization of incidents that must be reported to authorities. Reporting thresholds, audit systems, and the extent of the integration of voluntary reporting systems vary. Conclusion: Radiotherapy incidents are dealt with differently on an international level. Changes are to be expected based on the European Basic Safety Standards Directive that is currently being prepared and will have to be implemented nationally in due course. (orig.)

  8. 78 FR 48170 - Privacy Act of 1974; CMS Computer Match No. 2013-12; HHS Computer Match No. 1307; SSA Computer...

    Science.gov (United States)

    2013-08-07

    ....hhs.gov . SUPPLEMENTARY INFORMATION: The Computer Matching and Privacy Protection Act of 1988 (Public... computer matching involving Federal agencies could be performed and adding certain protections for... Affordability Programs under the Patient Protection and Affordable Care Act''. SECURITY CLASSIFICATION...

  9. Applying the ionising radiation regulations to radon in the UK workplace

    International Nuclear Information System (INIS)

    Denman, A. R.

    2008-01-01

    As a response to the identification of a health risk from workplace radon in the UK, the Ionising Radiations Regulations include the protection of workers from excessive levels of radon. Employers are required to make risk assessments, and the interpretation of the Health and Safety Executive is that the regulations apply to workplace premises in locations already designated as Radon Affected Areas for domestic purposes, with the difference that in workplaces, it is the maximum winter radon concentration rather than the annual average which is the parameter of interest. This paper discusses the rationale behind the current regulatory environment, outlines the role and duties of Accredited Radiation Protection Advisers and summarises the strategies necessary to conform to the regulations. (authors)

  10. 42 CFR 57.316 - What additional Department regulations apply to schools?

    Science.gov (United States)

    2010-10-01

    ... schools? 57.316 Section 57.316 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN... STUDENT LOANS Nursing Student Loans § 57.316 What additional Department regulations apply to schools? Participating schools are advised that in addition to complying with the terms and conditions of these...

  11. Drug Pricing Program Ceiling Price and Manufacturer Civil Monetary Penalties Regulation. Final rule; further delay of effective date.

    Science.gov (United States)

    2017-09-29

    The Health Resources and Services Administration (HRSA) administers section 340B of the Public Health Service Act (PHSA), known as the "340B Drug Pricing Program" or the "340B Program." HRSA published a final rule on January 5, 2017, that set forth the calculation of the ceiling price and application of civil monetary penalties. The final rule applied to all drug manufacturers that are required to make their drugs available to covered entities under the 340B Program. On August 21, 2017, HHS solicited comments on further delaying the effective date of the January 5, 2017, final rule to July 1, 2018 (82 FR 39553). HHS proposed this action to allow a more deliberate process of considering alternative and supplemental regulatory provisions and to allow for sufficient time for additional rulemaking. After consideration of the comments received on the proposed rule, HHS is delaying the effective date of the January 5, 2017, final rule, to July 1, 2018.

  12. 25 CFR 900.50 - What Federal laws, regulations, and Executive Orders apply to subcontractors?

    Science.gov (United States)

    2010-04-01

    ... SELF-DETERMINATION AND EDUCATION ASSISTANCE ACT Standards for Tribal or Tribal Organization Management..., regulations, and Executive Orders apply to subcontracts awarded under self-determination contracts. As a... 25 Indians 2 2010-04-01 2010-04-01 false What Federal laws, regulations, and Executive Orders...

  13. Defense Civil Support: DOD, HHS, and DHS Should Use Existing Coordination Mechanisms to Improve Their Pandemic Preparedness

    Science.gov (United States)

    2017-02-01

    documentation is not shared with a broad audience , HHS officials said that it is available to DOD stakeholders upon request, and as soon as it is approved...instructions to support incident relief efforts. • Alerts the NDMS FCCs to activate NDMS patient reception plans with a phased, regional approach and, when...patient reception areas, using available DOD transportation resources in coordination with the NDMS Medical Interagency Coordination Group

  14. 42 CFR 57.216 - What additional Department regulations apply to schools?

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false What additional Department regulations apply to schools? 57.216 Section 57.216 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN... schools? (a) Participating schools are advised that in addition to complying with the terms and conditions...

  15. 32 CFR 37.130 - Which other parts of the DoD Grant and Agreement Regulations apply to TIAs?

    Science.gov (United States)

    2010-07-01

    ... Regulations apply to TIAs? 37.130 Section 37.130 National Defense Department of Defense OFFICE OF THE... Which other parts of the DoD Grant and Agreement Regulations apply to TIAs? (a) TIAs are explicitly... information about assistance awards. (b) Two additional parts of the DoDGARs apply to TIAs, although they do...

  16. 42 CFR 59.1 - To what programs do these regulations apply?

    Science.gov (United States)

    2010-10-01

    ... FOR FAMILY PLANNING SERVICES Project Grants for Family Planning Services § 59.1 To what programs do... 42 Public Health 1 2010-10-01 2010-10-01 false To what programs do these regulations apply? 59.1... of voluntary family planning projects. These projects shall consist of the educational, comprehensive...

  17. 75 FR 30839 - Privacy Act of 1974; CMS Computer Match No. 2010-03, HHS Computer Match No. 1003, SSA Computer...

    Science.gov (United States)

    2010-06-02

    ... 1974; CMS Computer Match No. 2010-03, HHS Computer Match No. 1003, SSA Computer Match No. 1048, IRS... Services (CMS). ACTION: Notice of renewal of an existing computer matching program (CMP) that has an...'' section below for comment period. DATES: Effective Dates: CMS filed a report of the Computer Matching...

  18. 42 CFR 50.402 - To what program do these regulations apply?

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false To what program do these regulations apply? 50.402 Section 50.402 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS POLICIES OF GENERAL APPLICABILITY Public Health Service Grant Appeals Procedure § 50.402 To what program do...

  19. 48 CFR 301.607-72 - Applicability.

    Science.gov (United States)

    2010-10-01

    ... ACQUISITION REGULATION SYSTEM Career Development, Contracting Authority, and Responsibilities 301.607-72 Applicability. (a) The FAC-P/PM certification prerequisites and continuous learning requirements apply to all HHS employees who seek to obtain a FAC-P/PM certification. Although obtaining a FAC-P/PM certification...

  20. 36 CFR 3.2 - Do other boating laws and regulations apply to me when I operate my boat on park waters?

    Science.gov (United States)

    2010-07-01

    ... regulations apply to me when I operate my boat on park waters? 3.2 Section 3.2 Parks, Forests, and Public... boating laws and regulations apply to me when I operate my boat on park waters? (a) In addition to the.... NPS applies the adopted laws and regulations to vessels and their operation on all waters (navigable...

  1. 36 CFR 3.17 - What regulations apply to swimming areas and beaches?

    Science.gov (United States)

    2010-07-01

    ... swimming areas and beaches? 3.17 Section 3.17 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR BOATING AND WATER USE ACTIVITIES § 3.17 What regulations apply to swimming areas and beaches? (a) The superintendent may designate areas as swimming areas or swimming beaches in...

  2. 15 CFR 20.2 - Programs or activities to which these regulations apply.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Programs or activities to which these regulations apply. 20.2 Section 20.2 Commerce and Foreign Trade Office of the Secretary of Commerce... adopted by an elected, general purpose legislative body which: (i) Provides benefits or assistance to...

  3. Medicare depreciation; useful life guidelines--HCFA. Proposed rule.

    Science.gov (United States)

    1982-09-30

    We are proposing to amend Medicare regulations to clarify which useful life guidelines providers of health care services may use to determine the useful life of a depreciable asset for Medicare reimbursement purposes. Current regulations state that providers must utilize HHS useful life guidelines or, if none have been published by HHS, the American Hospital Association (AHA) useful life guidelines of 1973 or IRS guidelines. We are proposing to eliminate the reference to IRS guidelines because those previously acceptable for Medicare purposes are outdated and have been made obsolete by the IRS or by statutory change. We would also delete the specific reference to the 1973 AHA guidelines. In addition, we intend this amendment to clarify that certain tax legislation on accelerated depreciation, recently passed by Congress, does not apply to the Medicare program.

  4. 25 CFR 900.182 - What other statutes and regulations apply to FTCA coverage?

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false What other statutes and regulations apply to FTCA... HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES CONTRACTS UNDER THE INDIAN SELF-DETERMINATION AND EDUCATION ASSISTANCE ACT Federal Tort Claims Act Coverage General Provisions § 900.182 What other statutes...

  5. 25 CFR 1000.271 - What other statutes and regulations apply to FTCA coverage?

    Science.gov (United States)

    2010-04-01

    ... OF THE INTERIOR ANNUAL FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Federal Tort Claims § 1000.271 What other statutes and... 25 Indians 2 2010-04-01 2010-04-01 false What other statutes and regulations apply to FTCA...

  6. Blended Risk Approach in Applying PSA Models to Risk-Based Regulations

    International Nuclear Information System (INIS)

    Dimitrijevic, V. B.; Chapman, J. R.

    1996-01-01

    In this paper, the authors will discuss a modern approach in applying PSA models in risk-based regulation. The Blended Risk Approach is a combination of traditional and probabilistic processes. It is receiving increased attention in different industries in the U. S. and abroad. The use of the deterministic regulations and standards provides a proven and well understood basis on which to assess and communicate the impact of change to plant design and operation. Incorporation of traditional values into risk evaluation is working very well in the blended approach. This approach is very application specific. It includes multiple risk attributes, qualitative risk analysis, and basic deterministic principles. In blending deterministic and probabilistic principles, this approach ensures that the objectives of the traditional defense-in-depth concept are not compromised and the design basis of the plant is explicitly considered. (author)

  7. Stealth law: HIPAA's back-door regulation of "business associates".

    Science.gov (United States)

    Jacobson, James M

    2003-01-01

    The final HIPAA privacy modifications have substantially lightened the administrative, compliance, and liability loads borne by health plan and provider covered entities. Unlike under the original Clinton rules, for example, covered entities are no longer required to obtain patient consents, to monitor and mitigate the information practices of their business associates, or to treat patients as third-party beneficiaries of their business associate contracts. But the final modifications have done almost nothing to lessen the huge burdens and expense that will soon be imposed on those managed care entities that are merely business associates, a category that Congress never authorized HHS to regulate.

  8. Emotion processing and regulation in women with morbid obesity who apply for bariatric surgery

    NARCIS (Netherlands)

    Zijlstra, H.; Middendorp, H. van; Devaere, L.; Larsen, J.K.; van Ramshorst, B.; Geenen, R.

    2012-01-01

    Emotional eating, the tendency to eat when experiencing negative affect, is prevalent in morbid obesity and may indicate that ways to deal with emotions are disturbed. Our aim was to compare emotion processing and regulation between 102 women with morbid obesity who apply for bariatric surgery and

  9. 25 CFR 900.118 - Do these “construction contract” regulations apply to construction management services?

    Science.gov (United States)

    2010-04-01

    ... construction management services? 900.118 Section 900.118 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE...” regulations apply to construction management services? No. Construction management services may be contracted separately under section 108 of the Act. Construction management services consultants and/or Indian tribe or...

  10. 28 CFR 30.6 - What procedures apply to the selection of programs and activities under these regulations?

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false What procedures apply to the selection of programs and activities under these regulations? 30.6 Section 30.6 Judicial Administration DEPARTMENT OF... consult with local elected officials. (b) Each state that adopts a process shall notify the Attorney...

  11. Applying Web-Based Co-Regulated Learning to Develop Students' Learning and Involvement in a Blended Computing Course

    Science.gov (United States)

    Tsai, Chia-Wen

    2015-01-01

    This research investigated, via quasi-experiments, the effects of web-based co-regulated learning (CRL) on developing students' computing skills. Two classes of 68 undergraduates in a one-semester course titled "Applied Information Technology: Data Processing" were chosen for this research. The first class (CRL group, n = 38) received…

  12. 49 CFR 17.6 - What procedures apply to the selection of programs and activities under these regulations?

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false What procedures apply to the selection of programs and activities under these regulations? 17.6 Section 17.6 Transportation Office of the Secretary of Transportation INTERGOVERNMENTAL REVIEW OF DEPARTMENT OF TRANSPORTATION PROGRAMS AND ACTIVITIES § 17.6 What...

  13. Control of communicable disease; foreign--requirements for importers of nonhuman primates (NHP). Final rule.

    Science.gov (United States)

    2013-02-15

    The Centers for Disease Control and Prevention (CDC), located within the Department of Health and Human Services (HHS), is amending regulations for the importation of live nonhuman primates (NHPs) by extending existing requirements for the importation of Macaca fascicularis (cynomolgus), Chlorocebus aethiops (African green), and Macaca mulatta (rhesus) monkeys to all NHPs with the exception of the filovirus testing requirement. Filovirus testing will only be required for Old World NHPs in quarantine that have illness consistent with filovirus infection or that die for any reason other than trauma during quarantine. HHS/CDC is also finalizing a provision to reduce the frequency at which importers of cynomolgus, African green, and rhesus monkeys are required to renew their special permits (from every 180 days to every 2 years). HHS/CDC is incorporating existing guidelines into the regulations and adding new provisions to address the following: NHPs imported as part of an animal act; NHPs imported or transferred by zoological societies; the transfer of NHPs from approved laboratories; and non-live imported NHP products. Finally, HHS/CDC is also requiring that all NHPs be imported only through ports of entry where a HHS/CDC quarantine station is located.

  14. Discontinuation of approval of modifications in notes, guaranteed under Title VI or VII of the Public Health Service Act, proposed to permit use of the notes as collateral for tax-exempt financings--PHS. Final rule.

    Science.gov (United States)

    1983-09-21

    The Department of Health and Human Services (HHS) adds a new section to regulations for making and guaranteeing loans for construction and modernization of hospitals and medical facilities and to regulations for guaranteeing loans for the construction of teaching facilities for health professions personnel. Under these regulations HHS will not approve the modification of the terms of an existing loan guaranteed under Title VI or Title VII of the Public Health Service (PHS) Act if the modification would permit use of the guarantee (or guaranteed loan) as collateral for tax-exempt financing.

  15. 34 CFR 425.4 - What regulations apply?

    Science.gov (United States)

    2010-07-01

    ..., DEPARTMENT OF EDUCATION DEMONSTRATION PROJECTS FOR THE INTEGRATION OF VOCATIONAL AND ACADEMIC LEARNING... Projects for the Integration of Vocational and Academic Learning Program: (a) The regulations in this part...

  16. THEORETICAL AND PRACTICAL CONCEPTS REGARDING THE EXECUTION OF COMPLEMENTARY PUNISHMENTS APPLIED TO NATURAL PERSONS WITHIN THE REGULATION OF THE NEW CRIMINAL LEGISLATION

    Directory of Open Access Journals (Sweden)

    CRISTINA DANIELA MUNTEANU

    2013-05-01

    Full Text Available In this study we aim at analyzing the complementary punishments applied to natural persons as regulated by the new criminal legislation, our motivation being the numerous amendments brought by the new criminal legislation, respectively the increase of the number of complementary punishments, the change of their enforcement starting moment and such other changes that we intend to debate in this study. Considering the changes brought to the starting moment of the complementary punishment enforcement, we focused mainly on the enforcement and execution of complementary punishments applied to natural persons, exemplifying the execution manner of each punishment, respectively: in the context of applying the complementary punishment regarding the forbiddance of rights, military degradation or the newest complementary punishment to be applied to natural persons, the publishing of the judgment of conviction. The amendments to the starting moment of the complementary punishment enforcement were brought as a result of introducing the punishment by fine and criminal punishments which may be executed on probation, in addition to which a complementary punishment may be applied. Regarding the enforcement of judgments, we have to mention the fact that it constitutes an autonomous stage of the criminal trial, governed by the regulations provided under the Criminal Procedure Act. Nevertheless, not all activities related to the enforcement of judgments are included in this stage, but only the ones triggering the start of the judgment enforcement. Such aspect imposes itself, taking into consideration the distinction between the enforcement of a judgment and the actual execution of the punishment. Regarding the effective execution of a punishment, activity performed outside the criminal trial, it is subordinated, on one hand, to the regulations provided under the criminal law, and on the other hand, to the regulations regarding the execution of punishments and of

  17. 42 CFR 483.405 - Relationship to other HHS regulations.

    Science.gov (United States)

    2010-10-01

    ... SERVICES (CONTINUED) STANDARDS AND CERTIFICATION REQUIREMENTS FOR STATES AND LONG TERM CARE FACILITIES Conditions of Participation for Intermediate Care Facilities for the Mentally Retarded § 483.405 Relationship... participation under this Part, their violation may result in the termination or suspension of, or the refusal to...

  18. 340B Drug Pricing Program Ceiling Price and Manufacturer Civil Monetary Penalties Regulation. Final rule; further delay of effective date.

    Science.gov (United States)

    2017-05-19

    The Health Resources and Services Administration (HRSA) administers section 340B of the Public Health Service Act (PHSA), referred to as the "340B Drug Pricing Program" or the "340B Program." HRSA published a final rule on January 5, 2017, that set forth the calculation of the ceiling price and application of civil monetary penalties. The final rule applied to all drug manufacturers that are required to make their drugs available to covered entities under the 340B Program. In accordance with a January 20, 2017, memorandum from the Assistant to the President and Chief of Staff, entitled "Regulatory Freeze Pending Review," HRSA issued an interim final rule that delayed the effective date of the final rule published in the Federal Register (82 FR 1210, (January 5, 2017)) to May 22, 2017. HHS invited commenters to provide their views on whether a longer delay of the effective date to October 1, 2017, would be more appropriate. After consideration of the comments received on the interim final rule, HHS is delaying the effective date of the January 5, 2017 final rule, to October 1, 2017.

  19. Self-Regulated Learning Strategies Applied to Undergraduate, Graduate and Specialization Students from Civil Engineering

    Directory of Open Access Journals (Sweden)

    Jose Carlos Redaelli

    2013-03-01

    Full Text Available The current demand for civil engineering work requires new skills and knowledge and calls for new and effective learning methods. This paper shows self-regulated learning strategies applied to undergraduate, graduate and specialization students from Civil Engineering in a Brazilian University. A Scale of Evaluation of Learning Strategies was administered with a view to identifying students´ cognitive, metacognitive and dysfunctional learning strategies.

  20. 48 CFR 352.242-71 - Tobacco-free facilities.

    Science.gov (United States)

    2010-10-01

    ... personal or company vehicles operated by Contractor employees while on an HHS property. This policy also... HHS policy will apply to the maximum area permitted by both law and current lease agreements. The Contractor shall ensure that each of its employees, and any subcontractor staff, is made aware of, understand...

  1. 41 CFR 102-75.1160 - What definitions apply to this subpart?

    Science.gov (United States)

    2010-07-01

    ... to 40 U.S.C. 524. GSA means the United States General Services Administration. HHS means the United States Department of Health and Human Services. Homeless means— (1) An individual or family that lacks a... otherwise detained under an Act of Congress or a State law. HUD means the United States Department of...

  2. Inherited mutations in the helicase RTEL1 cause telomere dysfunction and Hoyeraal-Hreidarsson syndrome.

    Science.gov (United States)

    Deng, Zhong; Glousker, Galina; Molczan, Aliah; Fox, Alan J; Lamm, Noa; Dheekollu, Jayaraju; Weizman, Orr-El; Schertzer, Michael; Wang, Zhuo; Vladimirova, Olga; Schug, Jonathan; Aker, Memet; Londoño-Vallejo, Arturo; Kaestner, Klaus H; Lieberman, Paul M; Tzfati, Yehuda

    2013-09-03

    Telomeres repress the DNA damage response at the natural chromosome ends to prevent cell-cycle arrest and maintain genome stability. Telomeres are elongated by telomerase in a tightly regulated manner to ensure a sufficient number of cell divisions throughout life, yet prevent unlimited cell division and cancer development. Hoyeraal-Hreidarsson syndrome (HHS) is characterized by accelerated telomere shortening and a broad range of pathologies, including bone marrow failure, immunodeficiency, and developmental defects. HHS-causing mutations have previously been found in telomerase and the shelterin component telomeric repeat binding factor 1 (TRF1)-interacting nuclear factor 2 (TIN2). We identified by whole-genome exome sequencing compound heterozygous mutations in four siblings affected with HHS, in the gene encoding the regulator of telomere elongation helicase 1 (RTEL1). Rtel1 was identified in mouse by its genetic association with telomere length. However, its mechanism of action and whether it regulates telomere length in human remained unknown. Lymphoblastoid cell lines obtained from a patient and from the healthy parents carrying heterozygous RTEL1 mutations displayed telomere shortening, fragility and fusion, and growth defects in culture. Ectopic expression of WT RTEL1 suppressed the telomere shortening and growth defect, confirming the causal role of the RTEL1 mutations in HHS and demonstrating the essential function of human RTEL1 in telomere protection and elongation. Finally, we show that human RTEL1 interacts with the shelterin protein TRF1, providing a potential recruitment mechanism of RTEL1 to telomeres.

  3. Inherited mutations in the helicase RTEL1 cause telomere dysfunction and Hoyeraal–Hreidarsson syndrome

    Science.gov (United States)

    Deng, Zhong; Glousker, Galina; Molczan, Aliah; Fox, Alan J.; Lamm, Noa; Dheekollu, Jayaraju; Weizman, Orr-El; Schertzer, Michael; Wang, Zhuo; Vladimirova, Olga; Schug, Jonathan; Aker, Memet; Londoño-Vallejo, Arturo; Kaestner, Klaus H.; Lieberman, Paul M.; Tzfati, Yehuda

    2013-01-01

    Telomeres repress the DNA damage response at the natural chromosome ends to prevent cell-cycle arrest and maintain genome stability. Telomeres are elongated by telomerase in a tightly regulated manner to ensure a sufficient number of cell divisions throughout life, yet prevent unlimited cell division and cancer development. Hoyeraal–Hreidarsson syndrome (HHS) is characterized by accelerated telomere shortening and a broad range of pathologies, including bone marrow failure, immunodeficiency, and developmental defects. HHS-causing mutations have previously been found in telomerase and the shelterin component telomeric repeat binding factor 1 (TRF1)-interacting nuclear factor 2 (TIN2). We identified by whole-genome exome sequencing compound heterozygous mutations in four siblings affected with HHS, in the gene encoding the regulator of telomere elongation helicase 1 (RTEL1). Rtel1 was identified in mouse by its genetic association with telomere length. However, its mechanism of action and whether it regulates telomere length in human remained unknown. Lymphoblastoid cell lines obtained from a patient and from the healthy parents carrying heterozygous RTEL1 mutations displayed telomere shortening, fragility and fusion, and growth defects in culture. Ectopic expression of WT RTEL1 suppressed the telomere shortening and growth defect, confirming the causal role of the RTEL1 mutations in HHS and demonstrating the essential function of human RTEL1 in telomere protection and elongation. Finally, we show that human RTEL1 interacts with the shelterin protein TRF1, providing a potential recruitment mechanism of RTEL1 to telomeres. PMID:23959892

  4. Regulating Cannabis Manufacturing: Applying Public Health Best Practices from Tobacco Control.

    Science.gov (United States)

    Orenstein, Daniel G; Glantz, Stanton A

    2018-01-01

    State legalization and regulation of cannabis, despite continued federal illegality, is a massive shift in regulatory approach. Manufactured cannabis, including concentrates, extracts, edibles, tinctures, topicals and other products, has received less attention than more commonly used dried flower, but represents emerging regulatory challenges due to additives, potency, consumption methods, and abuse and misuse potential. In November 2017, the California Department of Public Health (CDPH) released initial cannabis manufacturing regulations as part of a new state regulatory structure. As the largest U.S. medical cannabis market (and largest legal adult use market in the world beginning in 2018), California's regulatory approach will potentially influence national and global policy. Comparing CDPH's initial regulations to tobacco control best practices reveals that, while the regulations recognize the need to protect public health, prioritizing public health over business interests requires stronger approaches to labeling, packaging, and product formulations. Based on tobacco best practices, we recommend that cannabis regulations incorporate large and proportionately sized informational labels, a prominent universal cannabis symbol, rotating and pictorial health warnings, mandatory plain packaging, a comprehensive ban on characterizing flavors and addictive additives, and strict limits on the potency of inhalable products and those easily confused with non-cannabis products.

  5. Human RTEL1 deficiency causes Hoyeraal-Hreidarsson syndrome with short telomeres and genome instability.

    Science.gov (United States)

    Le Guen, Tangui; Jullien, Laurent; Touzot, Fabien; Schertzer, Michael; Gaillard, Laetitia; Perderiset, Mylène; Carpentier, Wassila; Nitschke, Patrick; Picard, Capucine; Couillault, Gérard; Soulier, Jean; Fischer, Alain; Callebaut, Isabelle; Jabado, Nada; Londono-Vallejo, Arturo; de Villartay, Jean-Pierre; Revy, Patrick

    2013-08-15

    Hoyeraal-Hreidarsson syndrome (HHS), a severe variant of dyskeratosis congenita (DC), is characterized by early onset bone marrow failure, immunodeficiency and developmental defects. Several factors involved in telomere length maintenance and/or protection are defective in HHS/DC, underlining the relationship between telomere dysfunction and these diseases. By combining whole-genome linkage analysis and exome sequencing, we identified compound heterozygous RTEL1 (regulator of telomere elongation helicase 1) mutations in three patients with HHS from two unrelated families. RTEL1 is a DNA helicase that participates in DNA replication, DNA repair and telomere integrity. We show that, in addition to short telomeres, RTEL1-deficient cells from patients exhibit hallmarks of genome instability, including spontaneous DNA damage, anaphase bridges and telomeric aberrations. Collectively, these results identify RTEL1 as a novel HHS-causing gene and highlight its role as a genomic caretaker in humans.

  6. 32 CFR 37.1220 - Applied research.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Applied research. 37.1220 Section 37.1220... REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Definitions of Terms Used in This Part § 37.1220 Applied research..., Development, Test and Evaluation programs within Budget Activity 2, Applied Research (also known informally as...

  7. 48 CFR 311.7000 - Defining electronic information technology requirements.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Defining electronic information technology requirements. 311.7000 Section 311.7000 Federal Acquisition Regulations System HEALTH... Accessibility Standards 311.7000 Defining electronic information technology requirements. HHS staff that define...

  8. 75 FR 22809 - Mandatory Guidelines for Federal Workplace Drug Testing Programs

    Science.gov (United States)

    2010-04-30

    ... time for related training in Federal and federally-regulated workplace drug testing programs and will... related training in Federal and federally-regulated workplace drug testing programs, including HHS... DEPARTMENT OF HEALTH AND HUMAN SERVICES Mandatory Guidelines for Federal Workplace Drug Testing...

  9. Basis for applying for exemption according to species protection regulation. Final repository for spent nuclear fuel at Forsmark

    International Nuclear Information System (INIS)

    2011-02-01

    SKB will submit applications for permits and admissibility under the Environmental Act and under the Nuclear Activities Act to construct and operate a disposal facility for spent nuclear fuel at Forsmark. In the final repository the spent nuclear fuel from Swedish nuclear power plants is placed in order to protect human health and the environment against harmful effects of ionizing radiation. Construction and operation of the disposal facility in Forsmark will make an impact, give effects and consequences for the natural environment. Utilization of land for the construction of the facility and the impact on ground water as a result of groundwater drainage is expected to have negative consequences for the species included in species protection regulation. Thus, the planned activity require exemption from species protection regulation (SFS 2007:845). The purpose of this document is to provide a basis for an application for exemption under 14 paragraph species protection regulation from the prohibitions of 4, 6, 7 and 8 paragraph species protection regulation. A basis for the exemption application is that the proposed activity is considered to have an 'overriding public interest' prescribed in 14 paragraph species protection regulation. The document reports the impact, effects and consequences of the planned activities on species covered in the species protection regulation. The impact on protected species can be divided into two categories: - Direct effects on protected species and their habitats by utilization of the land. - Indirect effects on protected species and their habitats in the drainage of groundwater and the effect on groundwater levels. The document also includes a description of planned actions to prevent, restrict and compensate for the effects and consequences that the activity may cause. By applying for an exemption under 14 paragraph species protection regulation in a separate order from the application for permit according to chapters 9 and 11

  10. Constitutional mutations in RTEL1 cause severe dyskeratosis congenita.

    Science.gov (United States)

    Walne, Amanda J; Vulliamy, Tom; Kirwan, Michael; Plagnol, Vincent; Dokal, Inderjeet

    2013-03-07

    Dyskeratosis congenita (DC) and its phenotypically severe variant, Hoyeraal-Hreidarsson syndrome (HHS), are multisystem bone-marrow-failure syndromes in which the principal pathology is defective telomere maintenance. The genetic basis of many cases of DC and HHS remains unknown. Using whole-exome sequencing, we identified biallelic mutations in RTEL1, encoding a helicase essential for telomere maintenance and regulation of homologous recombination, in an individual with familial HHS. Additional screening of RTEL1 identified biallelic mutations in 6/23 index cases with HHS but none in 102 DC or DC-like cases. All 11 mutations in ten HHS individuals from seven families segregated in an autosomal-recessive manner, and telomere lengths were significantly shorter in cases than in controls (p = 0.0003). This group had significantly higher levels of telomeric circles, produced as a consequence of incorrect processing of telomere ends, than did controls (p = 0.0148). These biallelic RTEL1 mutations are responsible for a major subgroup (∼29%) of HHS. Our studies show that cells harboring these mutations have significant defects in telomere maintenance, but not in homologous recombination, and that incorrect resolution of T-loops is a mechanism for telomere shortening and disease causation in humans. They also demonstrate the severe multisystem consequences of its dysfunction. Copyright © 2013 The American Society of Human Genetics. Published by Elsevier Inc. All rights reserved.

  11. Rules and regulations applying to incidents in radiotheraphy; Rechtliche Grundlagen fuer den Umgang mit sicherheitsrelevanten Ereignissen in der Strahlentherapie

    Energy Technology Data Exchange (ETDEWEB)

    Lohr, F. [Universitaetsmedizin Mannheim, Heidelberg Univ., Mannheim (Germany). Klinik fuer Strahlentherapie und Radioonkologie; Baus, W. [Uniklinik Koeln (Germany). Klinik und Poliklinik fuer Strahlentherapie; Vorwerk, H. [Universitaetsklinikum Marburg-Giessen, Marburg Univ. (Germany). Klinik fuer Strahlentherapie; Schloemp, B. [Berufsverband der Medizinisch-Technischen Radiologieassistenten (MTRA) in der Radioonkologie (VMTRO), Berlin (Germany); Andre, L. [Lindenhofspital Bern (Switzerland); Georg, D. [Universitaetsklinik fuer Strahlentherapie der Medizinischen Univ. Wien/AKH Wien, Vienna (Austria). Abt. fuer Medizinische Strahlenphysik; Hodapp, N. [Universitaetsklinikum Freiburg, Freiburg Univ. (Germany). Klinik fuer Strahlenheilkunde

    2012-07-15

    Aims and purpose: Radiotherapy is an essential and reliable element of the treatment armamentarium in oncology. Numerous rules, regulations, and protocols minimize the associated risks. It can, however, never be excluded that errors in the treatment delivery chain result in inadequate tumor doses or unnecessary damage to organs at risk. A legal framework governs the management of such incidents. The most important European and North American regulations are reported. Results: Various directives issued by the European Union are differently implemented nationally. This applies particularly to the characterization of incidents that must be reported to authorities. Reporting thresholds, audit systems, and the extent of the integration of voluntary reporting systems vary. Conclusion: Radiotherapy incidents are dealt with differently on an international level. Changes are to be expected based on the European Basic Safety Standards Directive that is currently being prepared and will have to be implemented nationally in due course. (orig.)

  12. Branded prescription drug fee. Final regulations, temporary regulations, and removal of temporary regulations.

    Science.gov (United States)

    2014-07-28

    This document contains final regulations that provide guidance on the annual fee imposed on covered entities engaged in the business of manufacturing or importing branded prescription drugs. This fee was enacted by section 9008 of the Patient Protection and Affordable Care Act, as amended by section 1404 of the Health Care and Education Reconciliation Act of 2010. This document also withdraws the Branded Prescription Drug Fee temporary regulations and contains new temporary regulations regarding the definition of controlled group that apply beginning on January 1, 2015. The final regulations and the new temporary regulations affect persons engaged in the business of manufacturing or importing certain branded prescription drugs. The text of the temporary regulations in this document also serves as the text of proposed regulations set forth in a notice of proposed rulemaking (REG-123286-14) on this subject in the Proposed Rules section in this issue of the Federal Register.

  13. 45 CFR 1152.2 - What definitions apply to these regulations?

    Science.gov (United States)

    2010-10-01

    ... regulations? Chairman means the Chairman of the National Endowment for the Arts or an official or employee of the Endowment acting for the Chairman under a delegation of authority. Endowment means the National...

  14. Applying novel technologies and methods to inform the ontology of self-regulation.

    Science.gov (United States)

    Eisenberg, Ian W; Bissett, Patrick G; Canning, Jessica R; Dallery, Jesse; Enkavi, A Zeynep; Whitfield-Gabrieli, Susan; Gonzalez, Oscar; Green, Alan I; Greene, Mary Ann; Kiernan, Michaela; Kim, Sunny Jung; Li, Jamie; Lowe, Michael R; Mazza, Gina L; Metcalf, Stephen A; Onken, Lisa; Parikh, Sadev S; Peters, Ellen; Prochaska, Judith J; Scherer, Emily A; Stoeckel, Luke E; Valente, Matthew J; Wu, Jialing; Xie, Haiyi; MacKinnon, David P; Marsch, Lisa A; Poldrack, Russell A

    2018-02-01

    Self-regulation is a broad construct representing the general ability to recruit cognitive, motivational and emotional resources to achieve long-term goals. This construct has been implicated in a host of health-risk behaviors, and is a promising target for fostering beneficial behavior change. Despite its clear importance, the behavioral, psychological and neural components of self-regulation remain poorly understood, which contributes to theoretical inconsistencies and hinders maximally effective intervention development. We outline a research program that seeks to define a neuropsychological ontology of self-regulation, articulating the cognitive components that compose self-regulation, their relationships, and their associated measurements. The ontology will be informed by two large-scale approaches to assessing individual differences: first purely behaviorally using data collected via Amazon's Mechanical Turk, then coupled with neuroimaging data collected from a separate population. To validate the ontology and demonstrate its utility, we will then use it to contextualize health risk behaviors in two exemplar behavioral groups: overweight/obese adults who binge eat and smokers. After identifying ontological targets that precipitate maladaptive behavior, we will craft interventions that engage these targets. If successful, this work will provide a structured, holistic account of self-regulation in the form of an explicit ontology, which will better clarify the pattern of deficits related to maladaptive health behavior, and provide direction for more effective behavior change interventions. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Benefit using reasonable regulations in USA, how to skill up on professional engineers, apply international code, standard, and regulation

    International Nuclear Information System (INIS)

    Turner, S.L.; Morokuzu, Muneo; Amano, Osamu

    2005-01-01

    The reasonable regulations in USA consist of a graduated approach and a risk informed approach (RIA). RIA rationalizes the regulations on the basis of data of operations etc. PSA (Probabilistic Safety Assessment), a general method of RIA, is explained in detail. The benefits of nuclear power plant using RIA are increase of the rate of operation, visualization of risk, application of design standard and design, cost down of nuclear fuel cycle, waste, production and operation, and safety. RIA is supported by the field data, code, standard, regulation and professional engineers. The effects of introduction of RIA are explained. In order to introduce RIA in Japan, all the parties concerned such as the regulation authorities, the electric power industries, makers, universities, have to understand it and work together. A part of scientific society is stated. (S.Y.)

  16. Use of Federal Acquisition Regulation. Part 12. Contracts for Applied Research

    National Research Council Canada - National Science Library

    2001-01-01

    ...) Part 12, "Acquisition of Commercial Items,"contracts for acquiring applied research. Applied research involves the scientific efforts to translate basic research into solutions for broadly defined military needs...

  17. 48 CFR 301.607-77 - Governance.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Governance. 301.607-77 Section 301.607-77 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES GENERAL HHS... Governance. The Departmental ACM, in ASFR/OGAPA/DA, serves as the Departmental FAC-P/PM Program Manager and...

  18. Performance-based regulation. Panel Discussion

    International Nuclear Information System (INIS)

    Youngblood, Robert; Bier, Vicki M.; Bukowski, Richard W.; Prasad Kadambi, N.; Koonce, James F.

    2001-01-01

    Full text of publication follows: Performance-based regulation is a part of the NRC's Strategic Plan and is realizing steady progress in conceptual development for actual applications. For example, high-level, conceptual guidelines have been proposed that would apply to reactors, materials, and waste areas. Performance-based approaches are also being applied in other regulated industries such as FAA and OSHA. The discussion will include comments from speakers from different parts of the nuclear industry and other industries regarding benefits and weaknesses of performance-based regulation. (authors)

  19. Medical Examination of Aliens--Revisions to Medical Screening Process. Final rule.

    Science.gov (United States)

    2016-01-26

    The Centers for Disease Control and Prevention (CDC), within the Department of Health and Human Services (HHS), is issuing this final rule (FR) to amend its regulations governing medical examinations that aliens must undergo before they may be admitted to the United States. Based on public comment received, HHS/CDC did not make changes from the NPRM published on June 23, 2015. Accordingly, this FR will: Revise the definition of communicable disease of public health significance by removing chancroid, granuloma inguinale, and lymphogranuloma venereum as inadmissible health-related conditions for aliens seeking admission to the United States; update the notification of the health-related grounds of inadmissibility to include proof of vaccinations to align with existing requirements established by the Immigration and Nationality Act (INA); revise the definitions and evaluation criteria for mental disorders, drug abuse and drug addiction; clarify and revise the evaluation requirements for tuberculosis; clarify and revise the process for the HHS/CDC-appointed medical review board that convenes to reexamine the determination of a Class A medical condition based on an appeal; and update the titles and designations of federal agencies within the text of the regulation.

  20. 48 CFR 301.603-73 - Additional HHS training requirements.

    Science.gov (United States)

    2010-10-01

    ... Contract Specialist is not required to take the class as long as the Contract Specialist is working under... requirements. 301.603-73 Section 301.603-73 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES... each be 8 hours or more in length. (b) Performance based acquisition training. Effective January 1...

  1. Regulation Development for Drinking Water Contaminants

    Science.gov (United States)

    To explain what process and information underlies regulations including how the Safe Drinking Water Act applies to regulation development i.e. how does the drinking water law translate into regulations.

  2. Hilbert-Huang Spectrum as a new field for the identification of EEG event related de-/synchronization for BCI applications.

    Science.gov (United States)

    Panoulas, Konstantinos I; Hadjileontiadis, Leontios J; Panas, Stavros M

    2008-01-01

    Brain Computer Interfaces (BCI) usually utilize the suppression of mu-rhythm during actual or imagined motor activity. In order to create a BCI system, a signal processing method is required to extract features upon which the discrimination is based. In this article, the Empirical Mode Decomposition along with the Hilbert-Huang Spectrum (HHS) is found to contain the necessary information to be considered as an input to a discriminator. Also, since the HHS defines amplitude and instantaneous frequency for each sample, it can be used for an online BCI system. Experimental results when the HHS applied to EEG signals from an on-line database (BCI Competition III) show the potentiality of the proposed analysis to capture the imagined motor activity, contributing to a more enhanced BCI performance.

  3. 76 FR 51371 - Agency Information Collection Activities; Submission for Office of Management and Budget Review...

    Science.gov (United States)

    2011-08-18

    ... recall to comply with Sec. 107.260 for a total of 650 hours. As noted, we have added a new table 2 to... Request; Infant Formula Recall Regulations AGENCY: Food and Drug Administration, HHS. ACTION: Notice... collection of information to OMB for review and clearance. Infant Formula Recall Regulations--21 CFR 107.230...

  4. 7 CFR 37.4 - How to apply for service.

    Science.gov (United States)

    2010-01-01

    ... REGULATIONS PROGRAM TO ASSESS ORGANIC CERTIFYING AGENCIES § 37.4 How to apply for service. (a) Application. Any organic certifying agency may apply to the Branch Chief, Meat Grading and Certification (MGC...

  5. Nuclear regulation - the Canadian approach

    International Nuclear Information System (INIS)

    Jennekens, J.

    1981-09-01

    Although the Atomic Energy Control Board was established 35 years ago the basic philosophy of nuclear regulation in Canada and the underlying principles of the regulatory process remain essentially unchanged. This paper outlines the Canadian approach to nuclear regulation and explains in practical terms how the principles of regulation are applied. (author)

  6. Action threshold for applying insect growth regulators to tomato for management of irregular ripening caused by Bemisia argentifolii (Homoptera: Aleyrodidae).

    Science.gov (United States)

    Schuster, D J

    2002-04-01

    The whitefly Bemisia argentifolii Bellows & Perring is a major pest of tomatoes, causing an irregular ripening disorder characterized externally by incomplete or inhibited reddening of fruit, especially in longitudinal sections, and internally by an increase in the amount of white tissue. Experiments were undertaken during the spring and fall of 1997 and 1998 and the spring of 1999 to develop an action threshold for applying the insect growth regulators (IGRs) buprofezin and pyriproxyfen to manage B. argentifolii and irregular ripening. The IGRs were applied when predetermined thresholds were reached and were compared with a high rate of the systemic insecticide imidacloprid, which was applied at transplanting and provided season-long whitefly control. Only plots treated when the numbers of sessile nymphs (second through fourth instars) reached five per 10 leaflets consistently had both external and internal irregular ripening severity ratings similar to the imidacloprid standard. Results were similar for buprofezin and pyriproxyfen even though the modes of action differ. The five nymphs per 10 leaflets threshold lends itself to field scouting because nymphal counts completed in the field using the unaided eye supplemented with a 10x hand lens were linearly and significantly related to counts completed in the laboratory with a dissecting microscope.

  7. Low-level radioactive waste management: French and foreign regulations

    International Nuclear Information System (INIS)

    Coulon, R.

    1991-01-01

    This paper describes radioactive waste management regulations applied in USA, CANADA, SCANDINAVIA and FRANCE. For low level radioactive wastes, it is necessary to adapt waste management regulations which were firt definite for high level radioactive wastes. So the exemption concept is a simplification method of regulations applied to low radiation sources

  8. Global approaches to regulating electronic cigarettes

    Science.gov (United States)

    Kennedy, Ryan David; Awopegba, Ayodeji; De León, Elaine; Cohen, Joanna E

    2017-01-01

    Objectives Classify and describe the policy approaches used by countries to regulate e-cigarettes. Methods National policies regulating e-cigarettes were identified by (1) conducting web searches on Ministry of Health websites, and (2) broad web searches. The mechanisms used to regulate e-cigarettes were classified as new/amended laws, or existing laws. The policy domains identified include restrictions or prohibitions on product: sale, manufacturing, importation, distribution, use, product design including e-liquid ingredients, advertising/promotion/sponsorship, trademarks, and regulation requiring: taxation, health warning labels and child-safety standards. The classification of the policy was reviewed by a country expert. Results The search identified 68 countries that regulate e-cigarettes: 22 countries regulate e-cigarettes using existing regulations; 25 countries enacted new policies to regulate e-cigarettes; 7 countries made amendments to existing legislation; 14 countries use a combination of new/amended and existing regulation. Common policies include a minimum-age-of-purchase, indoor-use (vape-free public places) bans and marketing restrictions. Few countries are applying a tax to e-cigarettes. Conclusions A range of regulatory approaches are being applied to e-cigarettes globally; many countries regulate e-cigarettes using legislation not written for e-cigarettes. PMID:27903958

  9. Power-MOSFET Voltage Regulator

    Science.gov (United States)

    Miller, W. N.; Gray, O. E.

    1982-01-01

    Ninety-six parallel MOSFET devices with two-stage feedback circuit form a high-current dc voltage regulator that also acts as fully-on solid-state switch when fuel-cell out-put falls below regulated voltage. Ripple voltage is less than 20 mV, transient recovery time is less than 50 ms. Parallel MOSFET's act as high-current dc regulator and switch. Regulator can be used wherever large direct currents must be controlled. Can be applied to inverters, industrial furnaces photovoltaic solar generators, dc motors, and electric autos.

  10. 5 CFR 179.301 - Scope of regulations.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Scope of regulations. 179.301 Section 179.301 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS CLAIMS COLLECTION STANDARDS Administrative Offset § 179.301 Scope of regulations. These regulations apply to the...

  11. Panel presentation: Should some type of incentive regulation replace traditional methods for regulating LDCs?

    International Nuclear Information System (INIS)

    Costello, K.W.

    1992-01-01

    State regulators should consider new approaches to regulating LDCs. They should seriously look at different incentive systems, even if only as an experiment, to address the major inefficiencies they see plaguing LDCs. Regulators have become more receptive in recent years to applying different incentive systems for historically heavily regulated industries such as the telecommunications and electric industries. In view of prevailing conditions in the natural gas industry, there is no good reason why regulators should not be as receptive to applying incentive systems for LDCs. For gas services offered in competitive markets, regulators should ask themselves whether regulation is necessary any longer. For services still requiring regulation, regulators should explore whether changes in traditional regulation are needed. While some PUCs have undertaken new regulatory practices, the question before them today is whether they should do more; whether, for example, states should accelerate their efforts toward adopting more flexible pricing and other incentive-based regulations or toward considering deregulating selected services. PUCs have different options. They can choose from among a large number of incentive systems. Their choices should hinge upon what they view as major sources of inefficiencies. For example, if uneconomical bypass is perceived as a problem then different price rules might constitute the cornerstone of an incentive-based policy. On the other hand, if excessive purchased-gas costs seem to be a major problem, a PUC may want to consider abolishing the PGA or modifying it in a form that would eliminate the cost-plus component

  12. 48 CFR 370.302 - Types of assurances.

    Science.gov (United States)

    2010-10-01

    ....302 Section 370.302 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES HHS SUPPLEMENTATIONS SPECIAL PROGRAMS AFFECTING ACQUISITION Acquisitions Involving Human Subjects 370.302 Types of...'s current “List of Registered Institutional Review Boards (IRBs)/Independent Ethics Committees (IECs...

  13. 76 FR 368 - Agency Information Collection Activities; Announcement of Office of Management and Budget...

    Science.gov (United States)

    2011-01-04

    ... Food Safety and Applied Nutrition'' has been approved by the Office of Management and Budget (OMB... Food Safety and Applied Nutrition AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY... of Information Management, Food and Drug Administration, 1350 Piccard Dr., PI50-400B, Rockville, MD...

  14. Procedure manual: protocol for regulation of petroleum hydrocarbons in water under the special waste and contaminated sites regulation

    International Nuclear Information System (INIS)

    Evans, P.; Partridge, E.

    2002-05-01

    This document details the regulation governing numerical standards for petroleum hydrocarbons in water under the special waste and contaminated sites regulations of British Columbia. Groundwater containing benzene, toluene, ethylbenzene or xylenes in excess of the leachate standards is exempted from the regulatory regime of the Special Waste Regulation. The document contains a description of the conditions that apply to the management of petroleum hydrocarbons in water at contaminated sites. Some definitions are included, followed by an overview of the regulation. The third section deals with authorization and mandatory conditions, while additional requirements that might apply are enumerated in section four. This protocol directly affects the Environmental Management, and the Environmental Protection Regional Operations organizations. 1 tab

  15. Inhibition of the Hedgehog Signaling Pathway Depresses the Cigarette Smoke-Induced Malignant Transformation of 16HBE Cells on a Microfluidic Chip.

    Science.gov (United States)

    Qin, Yong-Xin; Yang, Zhi-Hui; Du, Xiao-Hui; Zhao, Hui; Liu, Yuan-Bin; Guo, Zhe; Wang, Qi

    2018-05-20

    The hedgehog signaling system (HHS) plays an important role in the regulation of cell proliferation and differentiation during the embryonic phases. However, little is known about the involvement of HHS in the malignant transformation of cells. This study aimed to detect the role of HHS in the malignant transformation of human bronchial epithelial (16HBE) cells. In this study, two microfluidic chips were designed to investigate cigarette smoke extract (CSE)-induced malignant transformation of cells. Chip A contained a concentration gradient generator, while chip B had four cell chambers with a central channel. The 16HBE cells cultured in chip A were used to determine the optimal concentration of CSE for inducing malignant transformation. The 16HBE cells in chip B were cultured with 12.25% CSE (Group A), 12.25% CSE + 5 μmol/L cyclopamine (Group B), or normal complete medium as control for 8 months (Group C), to establish the in vitro lung inflammatory-cancer transformation model. The transformed cells were inoculated into 20 nude mice as cells alone (Group 1) or cells with cyclopamine (Group 2) for tumorigenesis testing. Expression of HHS proteins was detected by Western blot. Data were expressed as mean ± standard deviation. The t-test was used for paired samples, and the difference among groups was analyzed using a one-way analysis of variance. The optimal concentration of CSE was 12.25%. Expression of HHS proteins increased during the process of malignant transformation (Group B vs. Group A, F = 7.65, P < 0.05). After CSE exposure for 8 months, there were significant changes in cellular morphology, which allowed the transformed cells to grow into tumors in 40 days after being inoculated into nude mice. Cyclopamine could effectively depress the expression of HHS proteins (Group C vs. Group B, F = 6.47, P < 0.05) and prevent tumor growth in nude mice (Group 2 vs. Group 1, t = 31.59, P < 0.01). The activity of HHS is upregulated during the CSE-induced malignant

  16. Ex Post Regulation as the Method of Sectoral Regulation in Electricity Sector

    Directory of Open Access Journals (Sweden)

    Rafał Nagaj

    2017-10-01

    Full Text Available Aim/purpose - The aim of the article is to present the essence of ex post approach to sectoral regulation, to show the advantages and disadvantages of ex post regulation and to answer the question whether it is worth using in the electricity sector. Design/methodology/approach - For this purpose, a critical analysis of expert literature was made and an empirical analysis of countries that have applied ex post regulation in the electricity sector in the European Union. Two research methods were used: a case study and a comparison of changes in price and quality of services. The research period covered the period 2000-2016. Findings - It was found that ex post regulation reduces regulatory costs, does not adversely affect the quality of service and long-term rates, gives businesses the freedom of decision-making and the ability to react quickly to changes in the economy. The main disadvantages of ex post regulation are the tendency for companies to over-estimate bills for consumers, the difficulty of pursuing claims by consumers and the need to shift regulatory risk to consumers. Research implications/limitations - In the paper there was identified a research gap, i.e. the effects of ex post regulation in the electricity sector in European Union countries where such regulation was applied. Identifying the research gap will help us understand what are the advantages and disadvantages of ex post regulation and will create a model for when it is good moment to implement this in the economy. Besides identifying the research gap, further studies will be required over ex post regulation. Originality/value/contribution - The additional value of the paper is the study of ex post regulation, its essence and types. The article analyzed the effects of ex post regulation in the electricity sector and provided valuable insights into the potential risks associated with this approach to economic regulation.

  17. 78 FR 20473 - National Practitioner Data Bank

    Science.gov (United States)

    2013-04-05

    ... Data Bank AGENCY: Health Resources and Services Administration (HRSA), HHS. ACTION: Final rule. SUMMARY... Bank, to incorporate statutory requirements under the Patient Protection and Affordable Care Act of... regulations which implemented the Healthcare Integrity and Protection Data Bank. Section 6403 of the...

  18. 77 FR 69630 - Agency Information Collection Activities; Proposed Collection; Comment Request; New Animal Drug...

    Science.gov (United States)

    2012-11-20

    ... must be assembled and submitted. The application must include safety and effectiveness data, proposed labeling, product manufacturing information, and where necessary, complete information on food safety... Applications and Supporting Regulations, and Form FDA 356V AGENCY: Food and Drug Administration, HHS. ACTION...

  19. Electrical installations and regulations

    CERN Document Server

    Whitfield, J F

    1966-01-01

    Electrical Installations and Regulations focuses on the regulations that apply to electrical installations and the reasons for them. Topics covered range from electrical science to alternating and direct current supplies, as well as equipment for providing protection against excess current. Cables, wiring systems, and final subcircuits are also considered, along with earthing, discharge lighting, and testing and inspection.Comprised of 12 chapters, this book begins with an overview of electrical installation work, traits of a good electrician, and the regulations governing installations. The r

  20. Health Education Assistance Loan (HEAL) Program. Final rule.

    Science.gov (United States)

    2017-11-15

    On July 1, 2014, the HEAL Program was transferred from the U.S. Department of Health and Human Services (HHS) to the U.S. Department of Education (the Department). To reflect this transfer and to facilitate the servicing of all HEAL loans that are currently held by the Department, the Secretary adds the HEAL Program regulations to the Department's chapter in the Code of Federal Regulations (CFR).

  1. 77 FR 25378 - Regulations Pertaining to the Disclosure of Return Information To Carry Out Eligibility...

    Science.gov (United States)

    2012-04-30

    ... return. Section 1413(a) of the Affordable Care Act directs the Secretary of HHS to establish a system... choose to obtain coverage through an Exchange will be eligible to qualify for a new premium tax credit... for the premium tax credit to help eligible individuals and families afford health insurance coverage...

  2. Exogenously applied plant growth regulators enhance the morpho-physiological growth and yield of rice under high temperature

    Directory of Open Access Journals (Sweden)

    Shah Fahad

    2016-08-01

    Full Text Available A two-year experiment was conducted to ascertain the effects of exogenously applied plant growth regulators (PGR on rice growth and yield attributes under high day (HDT and high night temperature (HNT. Two rice cultivars (IR-64 and Huanghuazhan were subjected to temperature treatments in controlled growth chambers and four different combinations of ascorbic acid (Vc, alpha-tocopherol (Ve, brassinosteroids (Br, methyl jasmonates (MeJA and triazoles (Tr were applied. High temperature severely affected rice morphology, and also reduced leaf area, above- and below-ground biomass, photosynthesis, and water use efficiency, while increased the leaf water potential of both rice cultivars. Grain yield and its related attributes except number of panicles, were reduced under high temperature. The HDT posed more negative effects on rice physiological attributes, while HNT was more detrimental for grain formation and yield. The Huanghuazhan performed better than IR-64 under high temperature stress with better growth and higher grain yield. Exogenous application of PGRs was helpful in alleviating the adverse effects of high temperature. Among PGR combinations, the Vc+Ve+MejA+Br was the most effective treatment for both cultivars under high temperature stress. The highest grain production by Vc+Ve+MejA+Br treated plants was due to enhanced photosynthesis, spikelet fertility and grain filling, which compensated the adversities of high temperature stress. Taken together, these results will be of worth for further understanding the adaptation and survival mechanisms of rice to high temperature and will assist in developing heat-resistant rice germplasm in future.

  3. 77 FR 75936 - Control of Communicable Diseases: Interstate; Scope and Definitions

    Science.gov (United States)

    2012-12-26

    ... add more current medical terminology where appropriate. HHS/CDC has determined that this NPRM is... proposing to update the definitions for interstate quarantine regulations to reflect modern terminology and..., under section 70.1, to reflect modern terminology and plain language commonly used by private sector...

  4. 48 CFR 319.202-2 - Locating small business sources.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Locating small business... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Policies 319.202-2 Locating small business sources. (a) OPDIVs shall foster, to the extent practicable, maximum participation by small businesses in HHS acquisitions...

  5. 76 FR 76415 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-12-07

    ... Health and Human Services (HHS) to make and enforce regulations necessary to prevent the introduction... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention [30 Day-12-11JQ... Project Data Collection for Evaluation of Education, Communication, and Training Activities--New--National...

  6. 75 FR 36092 - Agency Information Collection Activities; Proposed Collection; Comment Request; Medical Devices...

    Science.gov (United States)

    2010-06-24

    ... Good Manufacturing Practice Quality System Regulations AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is announcing an opportunity for public... existing collection of information, and to allow 60 days for public comment in response to the notice. This...

  7. 77 FR 11700 - Application, Review, and Reporting Process for Waivers for State Innovation

    Science.gov (United States)

    2012-02-27

    ... State Innovation AGENCY: Centers for Medicare & Medicaid Services (CMS), HHS; Department of the Treasury... of initial applications for a Waiver for State Innovation described in section 1332 of the Patient... Treasury (the Secretaries) to issue regulations regarding procedures for Waivers for State Innovation under...

  8. „The Control” in View of International Accounting Regulation and Romanian Accounting Regulation

    Directory of Open Access Journals (Sweden)

    Cristina Ciuraru-Andrica

    2010-12-01

    Full Text Available In Romania, financial reporting accountant is governed by Accounting Low number 82/1991, republished, and O.M.F.P. 3.055/2009 approving the accounting regulation in accordance with European Directives. To these are added the International Financial Reporting Standards (IFRS, IAS and IFRIC of which must take into account certain Romanian legal persons in accordance with applicable regulations. Therefore this paper presents the main points of the control from the two types of accounting regulations perspective (national and international applied in our country.

  9. Chemicals regulation and the Porter Hypothesis:a critical review of the new European chemicals regulation

    OpenAIRE

    Frohwein, T. (Torsten); Hansjürgens, B. (Bernd)

    2005-01-01

    In this contribution, discussions about the Porter Hypothesis and the pros and cons of the new European chemicals regulation system REACH are tied together. The contribution seeks to apply the Porter Hypothesis to the field of European chemicals regulation. Porter’s claim of positive effects of regulation on innovations seems especially important for the chemicals sector pursuing differentiation. But, understanding Porter’s concept of strategic management indicates that certain segments of th...

  10. 7 CFR 1.604 - What deadlines apply to pending applications?

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false What deadlines apply to pending applications? 1.604 Section 1.604 Agriculture Office of the Secretary of Agriculture ADMINISTRATIVE REGULATIONS Conditions in FERC Hydropower Licenses General Provisions § 1.604 What deadlines apply to pending applications? (a...

  11. Development of waste management regulations

    International Nuclear Information System (INIS)

    Elnour, E.G.

    2012-04-01

    Radioactive wastes are generated during nuclear fuel cycle operation, production and application of radioisotope in medicine, industry, research, and agriculture, and as a by product of natural resource exploitation, which includes mining and processing of ores. To ensure the protection of human health and the environment from the hazard of these wastes, a planned integrated radioactive waste management practice should be applied. The purpose of this study is to develop regulations for radioactive waste management for low and intermediate radioactive level waste (LILW), and other purpose of regulations is to establish requirements with which all organizations must comply in Sudan from LILW in particular disused/spent sources, not including radioactive waste for milling and mining practices. The national regulations regarding the radioactive waste management, should prescribe the allocation of responsibilities and roles of the Country, the regulatory body, user/owner, waste management organization, including regulations on transport packaging of waste and applied a quality assurance programme, to ensure that radioactive waste management is done safely and securely. (author)

  12. 76 FR 58007 - Privacy Act of 1974; Report of a New System of Records

    Science.gov (United States)

    2011-09-19

    ..., Division of Information Security & Privacy Management, Enterprise Architecture and Strategy Group, Office... system contain Protected Health Information (PHI) as defined by HHS regulation ``Standards for Privacy of... such PHI that are otherwise authorized by these routine uses may only be made if, and as, permitted or...

  13. 75 FR 1275 - New Animal Drugs; Ractopamine

    Science.gov (United States)

    2010-01-11

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration 21 CFR Part 558 [Docket No. FDA-2009-N-0665] New Animal Drugs; Ractopamine AGENCY: Food and Drug Administration, HHS. ACTION: Final rule. SUMMARY: The Food and Drug Administration (FDA) is amending the animal drug regulations to...

  14. 45 CFR 46.123 - Early termination of research support: Evaluation of applications and proposals.

    Science.gov (United States)

    2010-10-01

    ... of applications and proposals. 46.123 Section 46.123 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION PROTECTION OF HUMAN SUBJECTS Basic HHS Policy for Protection of Human... rights and welfare of human subjects (whether or not the research was subject to federal regulation). ...

  15. 48 CFR 352.231-70 - Salary rate limitation.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Salary rate limitation... Salary rate limitation. As prescribed in 331.101-70, the Contracting Officer shall insert the following clause: Salary Rate Limitation (January 2010) (a) Pursuant to the current and applicable prior HHS...

  16. 76 FR 61565 - Preemption Review

    Science.gov (United States)

    2011-10-05

    .... FDA-2011-N-0527] Preemption Review AGENCY: Food and Drug Administration, HHS. ACTION: Notification of preemption review. SUMMARY: The Food and Drug Administration (FDA) is announcing that it has determined, after conducting a review of its existing regulations issued within the past 10 years that contain...

  17. 78 FR 46347 - Agency Information Collection Activities; Proposed Collection; Comment Request; Medical Devices...

    Science.gov (United States)

    2013-07-31

    ... Good Manufacturing Practice Quality System Regulation AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is announcing an opportunity for public comment... information, and to allow 60 days for public comment in response to the notice. This notice solicits comments...

  18. 75 FR 13556 - Biocompatibles UK Ltd.; Filing of Color Additive Petition

    Science.gov (United States)

    2010-03-22

    ... filed a petition proposing that the color additive regulations be amended to provide for the safe use of...] Biocompatibles UK Ltd.; Filing of Color Additive Petition AGENCY: Food and Drug Administration, HHS. ACTION... polyvinyl alcohol as a color additive in vascular embolization devices. FOR FURTHER INFORMATION CONTACT...

  19. 48 CFR 307.104-70 - Acquisition strategy.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Acquisition strategy. 307... AND ACQUISITION PLANNING ACQUISITION PLANNING Acquisition Planning 307.104-70 Acquisition strategy... designated by the HHS CIO, DASFMP, the CAO, or the cognizant HCA) shall prepare an acquisition strategy using...

  20. 75 FR 11451 - New Animal Drugs for Use in Animal Feeds; Zilpaterol

    Science.gov (United States)

    2010-03-11

    .... FDA-2010-N-0002] New Animal Drugs for Use in Animal Feeds; Zilpaterol AGENCY: Food and Drug Administration, HHS. ACTION: Final rule. SUMMARY: The Food and Drug Administration (FDA) is amending the animal drug regulations to reflect approval of three abbreviated new animal drug applications (ANADAs) filed...

  1. 75 FR 24394 - Animal Drugs, Feeds, and Related Products; Withdrawal of Approval of a New Animal Drug...

    Science.gov (United States)

    2010-05-05

    ... [Docket No. FDA-2010-N-0002] Animal Drugs, Feeds, and Related Products; Withdrawal of Approval of a New Animal Drug Application; Buquinolate; Coumaphos AGENCY: Food and Drug Administration, HHS. ACTION: Final rule. SUMMARY: The Food and Drug Administration (FDA) is amending the animal drug regulations by...

  2. 41 CFR 102-34.35 - What definitions apply to this part?

    Science.gov (United States)

    2010-07-01

    ... dealership. (Procedures for purchasing and leasing motor vehicles through GSA can be found in 41 CFR subpart... Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION PERSONAL PROPERTY 34-MOTOR VEHICLE... definitions apply to this part: Commercial design motor vehicle means a motor vehicle procurable from regular...

  3. Emotion regulation strategies in Patients with schizophrenia

    NARCIS (Netherlands)

    van der Meer, Lisette; van't Wout, Mascha; Aleman, Andre

    2009-01-01

    Schizophrenia patients might experience difficulties in applying two widely used emotion regulation strategies, reappraisal and suppression. We investigated the relationships among emotion regulation strategies, alexithymia (i.e. inability to identify and verbalize feelings) and the role of

  4. TOWARD MORE EFFECTIVE REGULATION

    Energy Technology Data Exchange (ETDEWEB)

    J. GRAF

    2000-06-01

    This paper proposes a model relationship between the operator engaged in a hazardous activity, the regulator of that activity, and the general public. The roles and responsibilities of each entity are described in a way that allows effective communication flow. The role of the regulator is developed using the steam boiler as an example of a hazard subject to regulation; however, the model applies to any regulated activity. In this model the safety analyst has the extremely important role of communicating sometimes difficult technical information to the regulator in a way that the regulator can provide credible assurance to the general public as to the adequacy of the control of the hazardous activity. The conclusion asserts that acceptance of the model, understanding of the roles and responsibilities and definition of who communicates what information to whom will mitigate frustration on the part of each of the three entities.

  5. Harmonization of nuclear and radiation safety regulations for nuclear power plants with reference levels of Western European Nuclear Regulators Association (WENRA)

    International Nuclear Information System (INIS)

    Bojchuk, V.S.; Mikolajchuk, O.A.; Gromov, G.V.; Dibach, O.M.; Godovanyuk, G.M.; Nosovs'kij, A.V.

    2014-01-01

    Self-evaluation of the Ukrainian regulations on nuclear and radiation safety that apply to nuclear power plants for compliance with the reference levels of the Western European Nuclear Regulators Association (WENRA) is presented. Proposals on improvement of the regulations upon self-evaluation are provided

  6. 75 FR 31678 - Export Administration Regulations: Technical Corrections

    Science.gov (United States)

    2010-06-04

    ... and 774 [Docket No. 0907271167-91198-01] RIN 0694-AE69 Export Administration Regulations: Technical... clarifies language concerning the de minimis provisions of the Export Administration Regulations and certain... Items The Export Administration Regulations (EAR) generally do not apply to items that were made and are...

  7. 45 CFR 260.51 - What definitions apply to this subpart?

    Science.gov (United States)

    2010-10-01

    ... of Domestic Violence? § 260.51 What definitions apply to this subpart? Family Violence Option (or FVO... 45 Public Welfare 2 2010-10-01 2010-10-01 false What definitions apply to this subpart? 260.51 Section 260.51 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE...

  8. The European Regulation no. 761/2001 EMAS

    International Nuclear Information System (INIS)

    Andriola, L.; Battellini, S.

    2005-08-01

    The Regulation 761/2001 EMAS (Environmental Management and Audit Scheme), introduced by the 1836/93 Community regulation, is one of the tools activated by the European Union in order to apply the 5. and 6. Community Environmental Programme, in the field of firm-environment interactions at first (overcoming the old Command and Control logic), then by extending its applicability to ali Organisations. EMAS is a voluntary tool that enables Organisations to evaluate their own interaction with the Environment, to plan and check the yearly improvement of their environmental performance, providing the public documented relevant information. The report illustrates the procedure far applying this regulation, its implementation and new application trends in Italy and the advantages far firms [it

  9. 75 FR 17145 - Food Additives; Bisphenol A; Availability

    Science.gov (United States)

    2010-04-05

    ...] Food Additives; Bisphenol A; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice... contact materials. Uses of BPA were approved by FDA under its food additive regulations in the early 1960s..., Division of 2009 Food Contact Notifications, Office of Food Additive Safety, Center for Food Safety and...

  10. 76 FR 6326 - New Animal Drugs; Masitinib

    Science.gov (United States)

    2011-02-04

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration 21 CFR Parts 510 and 516 [Docket No. FDA-2011-N-0003] New Animal Drugs; Masitinib AGENCY: Food and Drug Administration, HHS. ACTION: Final rule. SUMMARY: The Food and Drug Administration (FDA) is amending the animal drug regulations to...

  11. 75 FR 79295 - New Animal Drugs; Mupirocin

    Science.gov (United States)

    2010-12-20

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration 21 CFR Parts 510 and 524 [Docket No. FDA-2010-N-0002] New Animal Drugs; Mupirocin AGENCY: Food and Drug Administration, HHS. ACTION: Final rule. SUMMARY: The Food and Drug Administration (FDA) is amending the animal drug regulations to...

  12. 48 CFR 352.239-70 - Standard for security configurations.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Standard for security... operating system patch level and anti-virus software level. Note: FDCC is applicable to all computing... applications operated on behalf of HHS are fully functional and operate correctly on systems configured in...

  13. 45 CFR 73.735-101 - Purpose.

    Science.gov (United States)

    2010-10-01

    ... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION STANDARDS OF CONDUCT General Provisions § 73.735-101 Purpose. To assure that the business of the Department of Health and Human Services... responsibilities. In accord with these principles, the regulations in this part are issued to inform HHS employees...

  14. 78 FR 1214 - Agency Information Collection Activities: Proposed Collection: Comment Request

    Science.gov (United States)

    2013-01-08

    ... OMB approval of the information collections contained in regulations found at 45 CFR Part 60 governing... the HIPDB was delegated by the HHS Office of the Inspector General to HRSA. This rule [[Page 1215..., to identify and discipline those who engage in unprofessional behavior; and to restrict the ability...

  15. 77 FR 8725 - Group Health Plans and Health Insurance Issuers Relating to Coverage of Preventive Services Under...

    Science.gov (United States)

    2012-02-15

    ... regulations authorizing the exemption of group health plans and group health insurance coverage sponsored by... plans and group health insurance issuers on April 16, 2012. FOR FURTHER INFORMATION CONTACT: Amy Turner... addition, information from HHS on private health insurance for consumers can be found on the CMS Web site...

  16. 76 FR 76894 - New Animal Drugs for Use in Animal Feeds; Tilmicosin

    Science.gov (United States)

    2011-12-09

    .... FDA-2011-N-0003] New Animal Drugs for Use in Animal Feeds; Tilmicosin AGENCY: Food and Drug Administration, HHS. ACTION: Final rule. SUMMARY: The Food and Drug Administration (FDA) is amending the animal drug regulations to reflect approval of a supplemental new animal drug application (NADA) filed by...

  17. 75 FR 9334 - New Animal Drugs for Use in Animal Feeds; Chlortetracycline

    Science.gov (United States)

    2010-03-02

    .... FDA-2010-N-0002] New Animal Drugs for Use in Animal Feeds; Chlortetracycline AGENCY: Food and Drug Administration, HHS. ACTION: Final rule. SUMMARY: The Food and Drug Administration (FDA) is amending the animal drug regulations to reflect approval of a supplemental new animal drug application (NADA) filed by ADM...

  18. 75 FR 54019 - New Animal Drugs for Use in Animal Feed; Ractopamine

    Science.gov (United States)

    2010-09-03

    .... FDA-2010-N-0002] New Animal Drugs for Use in Animal Feed; Ractopamine AGENCY: Food and Drug Administration, HHS. ACTION: Final rule. SUMMARY: The Food and Drug Administration (FDA) is amending the animal drug regulations to reflect approval of two supplemental new animal drug applications (NADAs) filed by...

  19. 75 FR 34361 - New Animal Drugs for Use in Animal Feeds; Florfenicol

    Science.gov (United States)

    2010-06-17

    .... FDA-2010-N-0002] New Animal Drugs for Use in Animal Feeds; Florfenicol AGENCY: Food and Drug Administration, HHS. ACTION: Final rule. SUMMARY: The Food and Drug Administration (FDA) is amending the animal drug regulations to reflect approval of a supplemental new animal drug application (NADA) filed by...

  20. 77 FR 24138 - New Animal Drugs for Use in Animal Feeds; Tiamulin

    Science.gov (United States)

    2012-04-23

    .... FDA-2012-N-0002] New Animal Drugs for Use in Animal Feeds; Tiamulin AGENCY: Food and Drug Administration, HHS. ACTION: Final rule. SUMMARY: The Food and Drug Administration (FDA) is amending the animal drug regulations to reflect approval of a supplemental new animal drug application (NADA) filed by...

  1. 77 FR 4228 - New Animal Drugs for Use in Animal Feeds; Monensin

    Science.gov (United States)

    2012-01-27

    .... FDA-2011-N-0003] New Animal Drugs for Use in Animal Feeds; Monensin AGENCY: Food and Drug Administration, HHS. ACTION: Final rule. SUMMARY: The Food and Drug Administration (FDA) is amending the animal drug regulations to reflect approval of a supplemental new animal drug application (NADA) filed by...

  2. 76 FR 79064 - New Animal Drugs for Use in Animal Feeds; Monensin

    Science.gov (United States)

    2011-12-21

    .... FDA-2011-N-0003] New Animal Drugs for Use in Animal Feeds; Monensin AGENCY: Food and Drug Administration, HHS. ACTION: Final rule. SUMMARY: The Food and Drug Administration (FDA) is amending the animal drug regulations to reflect approval of a supplemental new animal drug application (NADA) filed by...

  3. 34 CFR 490.4 - What definitions apply?

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false What definitions apply? 490.4 Section 490.4 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF VOCATIONAL AND ADULT EDUCATION... includes self-development, communication skills, job and financial skills development, education...

  4. Nuclear fuel cycle and legal regulations

    International Nuclear Information System (INIS)

    Shimoyama, Shunji; Kaneko, Koji.

    1980-01-01

    Nuclear fuel cycle is regulated as a whole in Japan by the law concerning regulation of nuclear raw materials, nuclear fuel materials and reactors (hereafter referred to as ''the law concerning regulation of reactors''), which was published in 1957, and has been amended 13 times. The law seeks to limit the use of atomic energy to peaceful objects, and nuclear fuel materials are controlled centering on the regulation of enterprises which employ nuclear fuel materials, namely regulating each enterprise. While the permission and report of uses are necessary for the employment of nuclear materials under Article 52 and 61 of the law concerning regulation of reactors, the permission provisions are not applied to three kinds of enterprises of refining, processing and reprocessing and the persons who install reactors as the exceptions in Article 52, when nuclear materials are used for the objects of the enterprises themselves. The enterprises of refining, processing and reprocessing and the persons who install reactors are stipulated respectively in the law. Accordingly the nuclear material regulations are applied only to the users of small quantity of such materials, namely universities, research institutes and hospitals. The nuclear fuel materials used in Japan which are imported under international contracts including the nuclear energy agreements between two countries are mostly covered by the security measures of IAEA as internationally controlled substances. (Okada, K.)

  5. 2 CFR 3513.20 - Does this part apply to me?

    Science.gov (United States)

    2010-01-01

    ... 2 Grants and Agreements 1 2010-01-01 2010-01-01 false Does this part apply to me? 3513.20 Section 3513.20 Grants and Agreements Federal Agency Regulations for Grants and Agreements EXPORT-IMPORT BANK OF THE UNITED STATES NONPROCUREMENT DEBARMENT AND SUSPENSION § 3513.20 Does this part apply to me...

  6. 2 CFR 801.20 - Does this part apply to me?

    Science.gov (United States)

    2010-01-01

    ... 2 Grants and Agreements 1 2010-01-01 2010-01-01 false Does this part apply to me? 801.20 Section 801.20 Grants and Agreements Federal Agency Regulations for Grants and Agreements DEPARTMENT OF VETERANS AFFAIRS NONPROCUREMENT DEBARMENT AND SUSPENSION § 801.20 Does this part apply to me? This part and...

  7. numerical assessment of conventional regulation effectiveness

    African Journals Online (AJOL)

    Benkoussas B, Djedjig R, and Vauquelin O

    2016-05-01

    May 1, 2016 ... The effectiveness of an underground smoke control system mainly depends on fire safety engineering that is ... In the same context, this work aims firstly, at investigating the effectiveness of conventional regulation applied to .... 5a). Fig.4. Station smoke behavior for conventional ventilation regulation. Fig.5a.

  8. 34 CFR 636.7 - What definitions apply?

    Science.gov (United States)

    2010-07-01

    ... cooperative arrangement for the purpose of carrying out common objectives. HEA means the Higher Education Act... 34 Education 3 2010-07-01 2010-07-01 false What definitions apply? 636.7 Section 636.7 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION...

  9. Fusion safety regulations in the United States: Progress and trends

    International Nuclear Information System (INIS)

    DeLooper, J.

    1994-01-01

    This paper explores the issue of regulations as they apply to current and future fusion experimental machines. It addresses fusion regulatory issues, current regulations used for fusion, the Tokamak Fusion Test Reactor experience with regulations, and future regulations to achieve fusion's safety and environmental potential

  10. 76 FR 55919 - Agency Information Collection Activities; Proposed Collection; Comment Request; MedWatch: The...

    Science.gov (United States)

    2011-09-09

    ... specified in sections 760 and 761 of the FD&C Act. Mandatory reporting of adverse reactions for human cells... this collection of information are health care professionals; medical care organizations and other user... http://vaers.hhs.gov/resources/vaers_form.pdf ) Hospitals are not required by Federal law or regulation...

  11. 76 FR 2807 - New Animal Drugs; Change of Sponsor

    Science.gov (United States)

    2011-01-18

    .... FDA-2010-N-0002] New Animal Drugs; Change of Sponsor AGENCY: Food and Drug Administration, HHS. ACTION: Final rule. SUMMARY: The Food and Drug Administration (FDA) is amending the animal drug regulations to...., Cambridge, MA 02141 has informed FDA that it has transferred ownership of, and all rights and interest in...

  12. 75 FR 5887 - New Animal Drugs for Use in Animal Feeds; Ractopamine; Monensin

    Science.gov (United States)

    2010-02-05

    .... FDA-2010-N-0002] New Animal Drugs for Use in Animal Feeds; Ractopamine; Monensin AGENCY: Food and Drug Administration, HHS. ACTION: Final rule. SUMMARY: The Food and Drug Administration (FDA) is amending the animal drug regulations to reflect approval of an original new animal drug application (NADA) filed by Elanco...

  13. 77 FR 22667 - New Animal Drugs for Use in Animal Feeds; Tiamulin

    Science.gov (United States)

    2012-04-17

    .... FDA-2012-N-0002] New Animal Drugs for Use in Animal Feeds; Tiamulin AGENCY: Food and Drug Administration, HHS. ACTION: Final rule. SUMMARY: The Food and Drug Administration (FDA) is amending the animal drug regulations to reflect the withdrawal of approval of those parts of a new animal drug application...

  14. 21 CFR 1271.350 - Reporting.

    Science.gov (United States)

    2010-04-01

    ... Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) REGULATIONS... section). Electronic Form FDA-3500A may be obtained at http://www.fda.gov/medwatch or at http://www.hhs... for which you performed a manufacturing step. (2) You must report any such HCT/P deviation relating to...

  15. Barbecue Basics: Tips to Prevent Foodborne Illness

    Medline Plus

    Full Text Available ... common links HHS U.S. Department of Health and Human Services U.S. Food and Drug Administration A to ... in FDA’s Center for Food Safety and Applied Nutrition. Wash hands. It seems basic, but not everyone ...

  16. 34 CFR 461.5 - What definitions apply?

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false What definitions apply? 461.5 Section 461.5 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF VOCATIONAL AND ADULT EDUCATION, DEPARTMENT OF EDUCATION ADULT EDUCATION STATE-ADMINISTERED BASIC GRANT PROGRAM General § 461.5 What...

  17. The regulations concerning the reprocessing business of spent fuels

    International Nuclear Information System (INIS)

    1978-01-01

    In compliance with ''The law for the regulations of nuclear source material, nuclear fuel material and reactors'' these regulations prescribe concerning reprocessing facilities: The procedures to apply for the approval of the design and method of construction and the approval of the change thereof; as well as the procedure to apply for the inspection of the facilities, and details of the inspection (in sections 2-6). After that, the regulations require the enterpriser of reprocessing business to keep necessary records and take necessary measures for safety concerning the facilities, operation of reprocessing equipments, and transportation, storage on disposal of used fuel, materials separated therefrom or materials contaminated by either of them (in sections 8-16). Further, the regulations prescribe the procedure to apply for the approval of the safety rule required to the enterpriser of reprocessing business by above mentioned law and specifies items which should be included into the rule (section 17). Moreover, the regulations require the enterpriser to submit reports of each use of the internationally controllled material and specifies the items which should be included into these reports (section 19). (Matsushima, A.)

  18. To regulate or not to regulate?

    Energy Technology Data Exchange (ETDEWEB)

    Mason, G.; Wrixon, A. [IAEA, Vienna (Austria)

    2006-07-01

    Full text of publication follows: In Hamlet famous soliloquy to be or not to be, he wrestles with the perennial human problem of choosing the right course of action in difficult circumstances. In recent years, we have witnessed a cast of thousands playing out a long-running scene that seems to echo Hamlet dilemma on a rather more prosaic level. When is it necessary to apply regulations to the control of exposure to ionizing radiation and when is regulatory control not warranted? This seemingly straightforward question has brought out the philosopher, ethician, lawyer, pragmatist, orator in simple radiation protection folk and has led to passionate debate on numerous occasions. This paper attempts an answer based on a review of recent developments. For deciding when to apply regulatory controls, several concepts have evolved over time, including exemption of practices and sources, exclusion of exposures and clearance of materials. These have different origins, purposes and characteristics. Exemption and clearance have often been associated with triviality of risk, while exclusion has been related to un-amenability of control. For each concept, criteria have been developed to assist the regulator in reaching a decision, but there has much disputation over numerical values. This paper briefly reviews and analyses recent developments and attempts to clarify the problem from first principles. The conclusion is that the underlying issue in each case is to determine when regulatory controls become unwarranted: that is, when the societal resources expended in applying them and complying with them would be disproportionate to any benefit they might bring. This is a natural extension of the principle of optimization of protection to the regulatory control of protection, in the context of exposure to radiation at very low levels. It also reflects common expectations of good governance: wise management of finite societal resources and avoidance of unwarranted controls on

  19. To regulate or not to regulate?

    International Nuclear Information System (INIS)

    Mason, G.; Wrixon, A.

    2006-01-01

    Full text of publication follows: In Hamlet famous soliloquy to be or not to be, he wrestles with the perennial human problem of choosing the right course of action in difficult circumstances. In recent years, we have witnessed a cast of thousands playing out a long-running scene that seems to echo Hamlet dilemma on a rather more prosaic level. When is it necessary to apply regulations to the control of exposure to ionizing radiation and when is regulatory control not warranted? This seemingly straightforward question has brought out the philosopher, ethician, lawyer, pragmatist, orator in simple radiation protection folk and has led to passionate debate on numerous occasions. This paper attempts an answer based on a review of recent developments. For deciding when to apply regulatory controls, several concepts have evolved over time, including exemption of practices and sources, exclusion of exposures and clearance of materials. These have different origins, purposes and characteristics. Exemption and clearance have often been associated with triviality of risk, while exclusion has been related to un-amenability of control. For each concept, criteria have been developed to assist the regulator in reaching a decision, but there has much disputation over numerical values. This paper briefly reviews and analyses recent developments and attempts to clarify the problem from first principles. The conclusion is that the underlying issue in each case is to determine when regulatory controls become unwarranted: that is, when the societal resources expended in applying them and complying with them would be disproportionate to any benefit they might bring. This is a natural extension of the principle of optimization of protection to the regulatory control of protection, in the context of exposure to radiation at very low levels. It also reflects common expectations of good governance: wise management of finite societal resources and avoidance of unwarranted controls on

  20. 34 CFR 462.3 - What definitions apply?

    Science.gov (United States)

    2010-07-01

    ... Education (also known as NRS Implementation Guidelines) posted on the Internet at: http://www.nrsweb.org. A... 34 Education 3 2010-07-01 2010-07-01 false What definitions apply? 462.3 Section 462.3 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF VOCATIONAL AND ADULT EDUCATION...

  1. 75 FR 22411 - Fonterra (USA) Inc.; Filing of Food Additive Petition

    Science.gov (United States)

    2010-04-28

    ...] Fonterra (USA) Inc.; Filing of Food Additive Petition AGENCY: Food and Drug Administration, HHS. ACTION... a petition proposing that the food additive regulations be amended to provide for the safe use of... that a food additive petition (FAP 0A4781) has been filed by Fonterra (USA), Inc., c/o Burdock Group...

  2. 75 FR 17928 - Nisso America, Inc.; Filing of Food Additive Petition

    Science.gov (United States)

    2010-04-08

    ...] Nisso America, Inc.; Filing of Food Additive Petition AGENCY: Food and Drug Administration, HHS. ACTION... a petition proposing that the food additive regulations for hydroxypropyl cellulose be amended by...) (21 U.S.C. 348(b)(5))), notice is given that a food additive petition (FAP 0A4780) has been filed by...

  3. 75 FR 10808 - CIBA Vision Corp.; Withdrawal of Color Additive Petitions

    Science.gov (United States)

    2010-03-09

    ...) proposing that the color additive regulations be amended to provide for the safe use of Color Index (C.I... of Color Additives Exempt from Certification (21 CFR part 73) to provide for the safe use of C.I...) CIBA Vision Corp.; Withdrawal of Color Additive Petitions AGENCY: Food and Drug Administration, HHS...

  4. 78 FR 7794 - National Institute of Environmental Health Sciences; Notice of Closed Meeting

    Science.gov (United States)

    2013-02-04

    ... Health Sciences Special Emphasis Panel, Sentinel Animal Study for Public Health. Date: February 27, 2013... from Environmental Exposures; 93.142, NIEHS Hazardous Waste Worker Health and Safety Training; 93.143...; 93.114, Applied Toxicological Research and Testing, National Institutes of Health, HHS) Dated...

  5. Responses of Rapid Viscoanalyzer Profile and Other Rice Grain Qualities to Exogenously Applied Plant Growth Regulators under High Day and High Night Temperatures.

    Directory of Open Access Journals (Sweden)

    Shah Fahad

    Full Text Available High-temperature stress degrades the grain quality of rice; nevertheless, the exogenous application of plant growth regulators (PGRs might alleviate the negative effects of high temperatures. In the present study, we investigated the responses of rice grain quality to exogenously applied PGRs under high day temperatures (HDT and high night temperatures (HNT under controlled conditions. Four different combinations of ascorbic acid (Vc, alpha-tocopherol (Ve, brassinosteroids (Br, methyl jasmonates (MeJA and triazoles (Tr were exogenously applied to two rice cultivars (IR-64 and Huanghuazhan prior to the high-temperature treatment. A Nothing applied Control (NAC was included for comparison. The results demonstrated that high-temperature stress was detrimental for grain appearance and milling qualities and that both HDT and HNT reduced the grain length, grain width, grain area, head rice percentage and milled rice percentage but increased the chalkiness percentage and percent area of endosperm chalkiness in both cultivars compared with ambient temperature (AT. Significantly higher grain breakdown, set back, consistence viscosity and gelatinization temperature, and significantly lower peak, trough and final viscosities were observed under high-temperature stress compared with AT. Thus, HNT was more devastating for grain quality than HDT. The exogenous application of PGRs ameliorated the adverse effects of high temperature in both rice cultivars, and Vc+Ve+MejA+Br was the best combination for both cultivars under high temperature stress.

  6. Negative Effects of Antimonopoly Regulation on the Russian Electric Power Industry

    Directory of Open Access Journals (Sweden)

    Elena NEPRINTSEVA

    2017-07-01

    Full Text Available With the antimonopoly regulation in the domestic economy getting more stringent an analysis of the current measures of antimonopoly regulation in terms of their efficiency is now becoming ever more relevant. The aim of the study - analyze how the measures of antimonopoly regulation affect competitive relationships in the electric power industry. The following methods have been used in this work: empirical method, cause-effect method and scientific abstraction method. The article sets out an analysis of the antimonopoly regulation measures that the antimonopoly authority applies. It also provides an assessment of consequences that follow from such methods being applied for the promotion of competitive relationships on the market of electric power and capacity. A conclusion has been reached that the antimonopoly regulation measures being applied impede the progress of competitive relationships on the market of electric power and capacity. The continuing process of reformation in electric power industry aims to liberalize relationships in the area of electric power production. Yet, as a result of this process, generating capacities are becoming increasingly more concentrated mainly around state companies. This is mainly caused by the lack of certainty regarding the results of the industry reformation and a more stringent state regulation over the last years of the reforms. At the same time, for the purposes of limiting the market force, measures of antimonopoly regulation are being applied to generating companies. Such measures have an adverse effect on competitive relationships and stimulate further concentration.

  7. Performance enhancement of microbial fuel cell by applying transient-state regulation

    International Nuclear Information System (INIS)

    Liang, Peng; Zhang, Changyong; Jiang, Yong; Bian, Yanhong; Zhang, Helan; Sun, Xueliang; Yang, Xufei; Zhang, Xiaoyuan; Huang, Xia

    2017-01-01

    Highlights: • MFC was operated with transient-state regulation to enhance its performance. • Effects of the TSR parameters on MFC performance were thoroughly investigated. • Long-term operation of MFC in TSR mode allowed 32.7% higher power production. • Anode capacitance helped reduce the MFC’s internal impedance in the TSR mode. - Abstract: A binder-free, pseudocapacitive anode was fabricated by coating reduced graphene oxide (rGO) and manganese oxide (MnO_2) nanoparticles on stainless steel fibre felt (SS). Microbial fuel cell (MFC) equipped with this novel anode yielded a maximum power density of 1045 mW m"−"2, 20 times higher than that of a similar MFC with a bare SS anode (46 mW m"−"2). Transient-state regulation (TSR) was implemented to further improve the MFC’s power generation. The optimal TSR duty cycle ranged from 67% to 95%, and the MFC’s power density increased with TSR frequency. A maximum power density output of 1238 mW m"−"2 was achieved at the TSR duty cycle of 75% and the frequency of 1 Hz, 18.4% greater than that obtained from the steady state operation. The TSR mode delivered better MFC performance especially when the external resistance was small. Long-term operation tests revealed that the current density and power density yielded in the TSR mode were on average 15.0% and 32.7% greater than those in the steady state mode, respectively. The TSR mode was believed to reduce the internal resistance of the MFC while enhance substrate mass transfer and electron transfer within the anode matrix, thereby improving the MFC performance.

  8. 76 FR 28193 - Amendments to Material Control and Accounting Regulations

    Science.gov (United States)

    2011-05-16

    ...] Amendments to Material Control and Accounting Regulations AGENCY: Nuclear Regulatory Commission. ACTION... amendments to the material control and accounting (MC&A) regulations. These regulations apply to NRC... ``accounting,'' and thus does not fully describe the accounting aspects that MC&A programs must include...

  9. 40 CFR 1068.40 - What special provisions apply for implementing changes in the regulations?

    Science.gov (United States)

    2010-07-01

    ... PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS GENERAL COMPLIANCE PROVISIONS FOR ENGINE PROGRAMS... may comply with earlier versions of applicable regulations as follows: (1) Prior to June 1, 2010, you...

  10. How EPA's Asbestos Regulations Apply to Residential Buildings Used for Fire Training

    Science.gov (United States)

    Memos and guidance from the Office of Air Quality Planning and Standards that clarify how the Asbestos National Emissions Standard for Hazardous Air Pollutants applies to residential buildings used for fire training, also known as acquired structures.

  11. 34 CFR 403.63 - How does a State carry out the State Vocational and Applied Technology Education Program?

    Science.gov (United States)

    2010-07-01

    ... Applied Technology Education Program? 403.63 Section 403.63 Education Regulations of the Offices of the... VOCATIONAL AND APPLIED TECHNOLOGY EDUCATION PROGRAM What Kinds of Activities Does the Secretary Assist Under... Technology Education Program? (a) Unless otherwise indicated in the regulations in this part, a State board...

  12. 76 FR 78866 - Nexira; Filing of Food Additive Petition

    Science.gov (United States)

    2011-12-20

    .... FDA-2011-F-0765] Nexira; Filing of Food Additive Petition AGENCY: Food and Drug Administration, HHS... filed a petition proposing that the food additive regulations be amended to provide for the expanded... Cosmetic Act (section 409(b)(5) (21 U.S.C. 348(b)(5))), notice is given that a food additive petition (FAP...

  13. 29 CFR 2204.103 - When the EAJA applies.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false When the EAJA applies. 2204.103 Section 2204.103 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH REVIEW COMMISSION IMPLEMENTATION OF THE EQUAL ACCESS TO JUSTICE ACT IN PROCEEDINGS BEFORE THE OCCUPATIONAL SAFETY AND HEALTH REVIEW...

  14. Public regulators and CSR

    DEFF Research Database (Denmark)

    Buhmann, Karin

    2016-01-01

    The social licence to operate (SLO) concept is little developed in the academic literature so far. Deployment of the term was made by the United National (UN) Guiding Principles on Business and Human Rights and the UN ‘Protect, Respect and Remedy’ Framework, which apply SLO as an argument...... for responsible business conduct, connecting to social expectations and bridging to public regulation. This UN guidance has had a significant bearing on how public regulators seek to influence business conduct beyond Human Rights to broader Corporate Social Responsibility (CSR) concerns. Drawing on examples...

  15. 12 CFR 225.174 - What aggregate thresholds apply to merchant banking investments?

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 3 2010-01-01 2010-01-01 false What aggregate thresholds apply to merchant banking investments? 225.174 Section 225.174 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF...) Regulations Merchant Banking Investments § 225.174 What aggregate thresholds apply to merchant banking...

  16. Applying Social Cognitive Theory to Academic Advising to Assess Student Learning Outcomes

    Science.gov (United States)

    Erlich, Richard J.; Russ-Eft, Darlene

    2011-01-01

    Review of social cognitive theory constructs of self-efficacy and self-regulated learning is applied to academic advising for the purposes of assessing student learning. A brief overview of the history of student learning outcomes in higher education is followed by an explanation of self-efficacy and self-regulated learning constructs and how they…

  17. The French Space Operation Act: Technical Regulations

    Science.gov (United States)

    Trinchero, J. P.; Lazare, B.

    2010-09-01

    The French Space Operation Act(FSOA) stipulates that a prime objective of the National technical regulations is to protect people, property, public health and the environment. Compliance with these technical regulations is mandatory as of 10 December 2010 for space operations by French space operators and for space operations from French territory. The space safety requirements and regulations governing procedures are based on national and international best practices and experience. A critical design review of the space system and procedures shall be carried out by the applicant, in order to verify compliance with the Technical Regulations. An independent technical assessment of the operation is delegated to CNES. The principles applied when drafting technical regulations are as follows: requirements must as far as possible establish the rules according to the objective to be obtained, rather than how it is to be achieved; requirements must give preference to international standards recognised as being the state of the art; requirements must take previous experience into account. Technical regulations are divided into three sections covering common requirements for the launch, control and return of a space object. A dedicated section will cover specific rules to be applied at the Guiana Space Centre. The main topics addressed by the technical regulations are: operator safety management system; study of risks to people, property, public health and the Earth’s environment; impact study on the outer space environment: space debris generated by the operation; planetary protection.

  18. Matrix converter applied to energy saving for street lighting systems

    OpenAIRE

    Román Lumbreras, Manuel; Velasco Quesada, Guillermo; Conesa Roca, Alfons

    2010-01-01

    This work presents a three-phase AC-AC converter, with independent phase control, based on matrix-converter structure. This converter is applied to electrical energy saving on the public lighting systems by means of regulation and control of the voltage applied to the lamps. The developed converter represents a technological improvement with respect to the traditional systems based on an autotransformer: it reduces system cost and volume, and increases lamps lifetime.

  19. 34 CFR 400.9 - What additional requirements govern the Vocational and Applied Technology Education Programs?

    Science.gov (United States)

    2010-07-01

    ... Applied Technology Education Programs? 400.9 Section 400.9 Education Regulations of the Offices of the... VOCATIONAL AND APPLIED TECHNOLOGY EDUCATION PROGRAMS-GENERAL PROVISIONS § 400.9 What additional requirements govern the Vocational and Applied Technology Education Programs? In addition to the Act, applicable...

  20. Successful emotion regulation requires both conviction and skill: beliefs about the controllability of emotions, reappraisal, and regulation success.

    Science.gov (United States)

    Gutentag, Tony; Halperin, Eran; Porat, Roni; Bigman, Yochanan E; Tamir, Maya

    2017-09-01

    To succeed in self-regulation, people need to believe that it is possible to change behaviour and they also need to use effective means to enable such a change. We propose that this also applies to emotion regulation. In two studies, we found that people were most successful in emotion regulation, the more they believed emotions can be controlled and the more they used an effective emotion regulation strategy - namely, cognitive reappraisal. Cognitive reappraisal moderated the link between beliefs about the controllability of emotion and success in emotion regulation, when reappraisal was measured as a trait (Study 1) or manipulated (Study 2). Such moderation was found when examining the regulation of disgust elicited by emotion-inducing films (Study 1), and the regulation of anger elicited by real political events (Study 2). We discuss the implications of our findings for research and practice in emotion regulation.

  1. 75 FR 78719 - National Institute of Environmental Health Sciences; Notice of Closed Meetings

    Science.gov (United States)

    2010-12-16

    ... for Laboratory Animal Pain Assessment. Date: January 10, 2011. Time: 9 a.m. to 10 a.m. Agenda: To... from Environmental Exposures; 93.142, NIEHS Hazardous Waste Worker Health and Safety Training; 93.143...; 93.114, Applied Toxicological Research and Testing, National Institutes of Health, HHS) Dated...

  2. 76 FR 47591 - Agency Information Collection Activities: Proposed Collection; Comment Request; Correction

    Science.gov (United States)

    2011-08-05

    ... State reserve requirements, in the form of Start-up Loans and Solvency Loans. An applicant may apply for...; Correction AGENCY: Centers for Medicare & Medicaid Services, HHS. In compliance with the requirement of... issuer. Solvency Loans are intended to assist loan recipients with meeting the solvency requirements of...

  3. 48 CFR 339.101 - Policy.

    Science.gov (United States)

    2010-10-01

    ... the latter term, see http://www.hhs.gov/ocio/policy.) An HHS information security policy waiver, the template for which is available at: http://intranet.hhs.gov/infosec/policies_memos.html, must be approved.... An HHS information security policy waiver, the template for which is available at: http://intranet...

  4. Defence in Depth - Applied to the Nuclear System

    Energy Technology Data Exchange (ETDEWEB)

    Weightman, M., E-mail: mike_weightman@hotmail.com

    2014-10-15

    Full text: Normally, the Defence in Depth concept is applied to the technical barriers that provide protection to the public and workers from nuclear accidents. This allows designers, operators and regulators to challenge (along with using other design principles such as independence, redundancy, diversity, single point failure, etc) the technical systems provided to see whether more needs to be done to provide adequate defence in depth to ensure risks are reduced so far as is reasonably practical. Post Fukushima, much thought has gone into reconsidering whether the effectiveness of the defence in depth concept can be enhanced by, for example, rebalancing the attention between prevention and mitigation or enhancing the independence of protective measures such as providing extremely robust standalone emergency cooling capability. This presentation argues that Fukushima teaches us a more fundamental lesson - that the defence in depth concept (along with other design principles') should be applied to the nuclear system to see whether more should be done to enhance the institutional barriers in any particular nuclear system. These barriers are at three main levels: industry, regulators and stakeholders each with sub-barriers. It reinforces the need for industry and regulators to be independent, open and transparent so that the nuclear system can work effectively. Examples are given where the application of the model identifies areas for improvement in existing systems. (author)

  5. Swelling of polymer networks with topological constraints: Application of the Helmis-Heinrich-Straube model

    Directory of Open Access Journals (Sweden)

    B. Basterra-Beroiz

    2018-08-01

    Full Text Available For the first time since its formulation in 1986, the theoretical approach proposed by Helmis, Heinrich and Straube (HHS model, which considers the contribution of topological restrictions from entanglements to the swelling of polymer networks, is applied to experimental data. The main aspects and key equations are reviewed and their application is illustrated for unfilled rubber compounds. The HHS model is based on real networks and gives new perspectives to the interpretation of experimental swelling data for which the entanglement contributions are usually neglected by considering phantom network models. This investigation applies a reliable constrained-chain approach through a deformation-dependent tube model for defining the elastic contribution of swollen networks, which is one of the main limitations on the applicability of classical (affine Flory-Rehner and (non-affine phantom models. This short communication intends to provide a baseline for the application and validation of this modern approach for a broader class of rubber materials.

  6. 42 CFR 65a.1 - To what programs do these regulations apply?

    Science.gov (United States)

    2010-10-01

    ... (see parts 63 and 64a of this chapter), or (4) Research training support under the NIH AIDS Research..., INTERNSHIPS, TRAINING NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES HAZARDOUS SUBSTANCES BASIC RESEARCH... part apply to the award of grants to support programs for basic research and training directed towards...

  7. 40 CFR 152.6 - Substances excluded from regulation by FIFRA.

    Science.gov (United States)

    2010-07-01

    ... utilization of applied nitrogen. (ii) Reduces leaching of applied nitrogen or reduces groundwater nitrogen... from FIFRA regulation if they meet the specified conditions or criteria. (a) Liquid chemical sterilants...

  8. Incentive regulation of nuclear power plants by state regulators

    International Nuclear Information System (INIS)

    Martin, R.L.; Baker, K.; Olson, J.

    1991-02-01

    The Nuclear Regulatory Commission (NRC) monitors incentive programs established by state regulators in order to obtain current information and to consider the potential safety effects of the incentive programs as applied to nuclear units. The current report is an update of NUREG/CR-5509, Incentive Regulation of Nuclear Power Plants by State Public Utility Commissions, published in December 1989. The information in this report was obtained from interviews conducted with each state regulator and each utility with a minimum entitlement of 10%. The agreements, orders, and settlements from which each incentive program was implemented were reviewed as required. The interviews and supporting documentation form the basis for the individual state reports describing the structure and financial impact of each incentive program. The programs currently in effect represent the adoption of an existing nuclear performance incentive program proposal and one new program. In addition, since 1989 a number of nuclear units have been included in one existing program; while one program was discontinued and another one concluded. 6 refs., 27 tabs

  9. Regulations for radiation protection in industrial radiography

    International Nuclear Information System (INIS)

    1974-01-01

    These Regulations specify that responsibility for applying radiation protection regulations in industrial radiography rests with the owner of the establishment who will designate a radiation protection officer to this effect. They provide for the organisation of radiation protection, including the measures to be observed, exposure limits, etc. The competent authority for these questions is the State Institute of Radiation Hygiene [fr

  10. 24 CFR 1000.18 - What environmental review requirements apply?

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false What environmental review requirements apply? 1000.18 Section 1000.18 Housing and Urban Development Regulations Relating to Housing and... HOUSING AND URBAN DEVELOPMENT NATIVE AMERICAN HOUSING ACTIVITIES General § 1000.18 What environmental...

  11. Ceramide-induced TCR up-regulation

    DEFF Research Database (Denmark)

    Menné, C; Lauritsen, Jens Peter Holst; Dietrich, J

    2000-01-01

    to increase T cell responsiveness. The purpose of this study was to identify and characterize potential pathways for TCR up-regulation. We found that ceramide affected TCR recycling dynamics and induced TCR up-regulation in a concentration- and time-dependent manner. Experiments applying phosphatase......The TCR is a constitutively recycling receptor meaning that a constant fraction of TCR from the plasma membrane is transported inside the cell at the same time as a constant fraction of TCR from the intracellular pool is transported to the plasma membrane. TCR recycling is affected by protein...... kinase C activity. Thus, an increase in protein kinase C activity affects TCR recycling kinetics leading to a new TCR equilibrium with a reduced level of TCR expressed at the T cell surface. Down-regulation of TCR expression compromises T cell activation. Conversely, TCR up-regulation is expected...

  12. A longitudinal study of risk factors for community-based home help services in Alzheimer’s disease: the influence of cholinesterase inhibitor therapy

    Directory of Open Access Journals (Sweden)

    Wattmo C

    2013-03-01

    Full Text Available Carina Wattmo, Elisabeth Paulsson, Lennart Minthon, Elisabet LondosClinical Memory Research Unit, Department of Clinical Sciences, Malmö, Lund University, Malmö, SwedenBackground: To investigate the long-term effects of cholinesterase inhibitor (ChEI therapy and the influence of sociodemographic and clinical factors on the use of community-based home help services (HHS by patients with Alzheimer’s disease (AD.Methods: This 3-year, prospective, multicenter study included 880 AD patients treated with donepezil, rivastigmine, or galantamine in a routine clinical setting. At baseline and every 6 months, the patients were assessed with several rating scales, including the Mini-Mental State Examination, Instrumental Activities of Daily Living (IADL, and Physical Self-Maintenance Scale. Doses of ChEI and amounts of HHS per week were recorded. Cox regression models were used to predict the time to HHS, and multiple linear regression was used to predict the volume of HHS used.Results: During the study, 332 patients (38% used HHS. Factors that both postponed HHS use and predicted lower amounts of HHS were higher doses of ChEIs, better IADL ability, and living with family. Men, younger individuals, and those with a slower IADL decline showed a longer time to HHS, whereas female sex, a lower cognitive status, or more medications at baseline predicted fewer hours of HHS.Conclusions: Higher doses of ChEI might reduce the use of HHS, possibly reducing the costs of community-based care. Female spouses provide more informal care than do male spouses, so the likelihood of using HHS is greater among women with AD. The "silent group" of more cognitively impaired and frail elderly AD patients receives less HHS, which might precipitate institutionalization.Keywords: cognition, activities of daily living, treatment effect, gender, predictors

  13. ASDTIC control and standardized interface circuits applied to buck, parallel and buck-boost dc to dc power converters

    Science.gov (United States)

    Schoenfeld, A. D.; Yu, Y.

    1973-01-01

    Versatile standardized pulse modulation nondissipatively regulated control signal processing circuits were applied to three most commonly used dc to dc power converter configurations: (1) the series switching buck-regulator, (2) the pulse modulated parallel inverter, and (3) the buck-boost converter. The unique control concept and the commonality of control functions for all switching regulators have resulted in improved static and dynamic performance and control circuit standardization. New power-circuit technology was also applied to enhance reliability and to achieve optimum weight and efficiency.

  14. The Regulated Third Sector: Administrative Practices Of Citizenship And Constitutional Efficiency Applied

    Directory of Open Access Journals (Sweden)

    Mateus Moura de Oliveira

    2016-12-01

    Full Text Available Beginning from an approach about the evolution of organizational models of the States, this work goals, initially, outline the evolution of these models in the Brazilian State, analyzing the development of the Third Sector as an exponent of the Managing State. Establish afterwards the development of the entities of civil society and the urge for its regulation due to dissemination of its many species. After short report of the most recent regulatory practices, the importance of the Sector concludes itself as apex of the active role of citizenship, whereas advocate the constitutional efficiency in the atuation of such entities.

  15. Towards a just and fair Internet: applying Rawls’ principles of justice to Internet regulation

    NARCIS (Netherlands)

    Douglas, David

    2015-01-01

    I suggest that the social justice issues raised by Internet regulation be exposed and examined by using a methodology adapted from that described by John Rawls in A Theory of Justice. Rawls’ theory uses the hypothetical scenario of people deliberating about the justice of social institutions from

  16. Does electricity (and heat) network regulation have anything to learn from fixed line telecoms regulation?

    International Nuclear Information System (INIS)

    Pollitt, Michael

    2010-01-01

    The purpose of this paper is to examine the lessons from the recent history of telecoms deregulation for electricity (and by implication heat) network regulation. We do this in the context of Ofgem's RPI-X rate at 20 review of energy regulation in the UK, which considers whether RPI-X-based price regulation is fit for purpose after over 20 years of operation in energy networks. We examine the deregulation of fixed line telecoms in the UK and the lessons which it seems to suggest. We then apply the lessons to electricity networks in the context of a possible increase in distributed generation directly connected to local distribution networks. We conclude that there is the possibility of more parallels over time and suggest several implications of this for the regulation of electricity and heat networks. (author)

  17. Initial state regulation of investor-owned utilities

    International Nuclear Information System (INIS)

    Savitski, D.W.

    2001-01-01

    This paper examines state initiation of public service (or utility) commission regulation of investor-owned utilities (IOUs) using an economic theory of regulation. The decision to regulate IOUs is assumed to have depended on the strength of competing interest groups, e.g. consumers and producers, and on institutional factors, e.g. whether commissioners were appointed or elected. Regulators, which then had jurisdiction over IOU rates, are assumed to have been optimizing agents. The potential benefits of regulation, in turn, translated into pressure to initiate regulation. To test this, a hazard model is applied to state-level data. On the demand side of the regulation market, the distribution of federal power and population density were unrelated, while a set of time dummies was positively related to the probability that a state initiated regulation. On the supply side, the fraction of the population that was urban and whether the governor was Republican or not were positively and negatively related to this probability

  18. Vessel Sewage Discharges: Statutes, Regulations, and Related Laws and Treaties

    Science.gov (United States)

    Vessel sewage discharges can be regulated under multiple statutes, regulations, and laws/treaties, including the Clean Water Act, Title XIV, MARPOL Annex IV and the Vessel General Permit. This page describes how these are applied to vessel sewage.

  19. Hypothenar hammer syndrome.

    Science.gov (United States)

    Schröttle, Angelika; Czihal, Michael; Lottspeich, Christian; Kuhlencordt, Peter; Nowak, Dennis; Hoffmann, Ulrich

    2015-05-01

    The diagnosis of hypothenar hammer syndrome (HHS) should be considered in the case of hand ischemia in people who occupationally or recreationally use the hypothenar region literally as a “hammer”. Routine diagnostics should consist of physical examination including Allen’s test, acral plethysmography and duplex sonography. According to the prevailing opinion angiography remains the «gold standard test» for establishing the diagnosis of HHS. Early diagnosis allows more effective therapeutic strategies and is important to prevent long-term negative medical sequelae. Several basic principles apply to all patients, for example hand protection and smoking cessation. The optimal treatment options, particularly the indication for surgery, remain controversial due to a lack of sound data from case series or prospective randomized trials.

  20. 76 FR 31545 - Federal Management Regulation; Motor Vehicle Management

    Science.gov (United States)

    2011-06-01

    ...; Sequence 1] RIN 3090-AJ14 Federal Management Regulation; Motor Vehicle Management AGENCY: Office of... Services Administration is proposing to amend the Federal Management Regulation (FMR) by revising current....C. 553(a)(2) because it applies to agency management. However, this proposed rule is being published...

  1. 76 FR 9079 - Revision of Distilled Spirits Plant Regulations

    Science.gov (United States)

    2011-02-16

    ... materials. This term does not apply to wine and beer, which generally are products of fermentation alone... category, TTB should create category-specific regulations, similar to the regulations for vinegar plants and alcohol fuel plants. TTB Response: TTB notes that vinegar plants and alcohol fuel plants differ...

  2. Regulation on Radiation Safety of Guatemala

    International Nuclear Information System (INIS)

    2001-03-01

    This regulation includes all the requirements administrative, radiation protection, that licensees must meet in order to obtain authorization from the competent authority to apply and use radiation sources, equipment emiting ionizing radiation in different practices authorized

  3. 40 CFR 80.840 - What requirements apply to transmix processors?

    Science.gov (United States)

    2010-07-01

    ... PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Toxics Gasoline Toxics Performance Requirements § 80.840 What requirements apply to transmix processors? Any transmix processor who produces gasoline or gasoline blendstock from transmix, or recovers gasoline or gasoline blendstock from transmix...

  4. 40 CFR 80.375 - What requirements apply to California gasoline?

    Science.gov (United States)

    2010-07-01

    ... gasoline? 80.375 Section 80.375 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Sulfur Exemptions § 80.375 What requirements apply to California gasoline? (a) Definition. For purposes of this subpart California gasoline...

  5. 40 CFR 80.1236 - What requirements apply to California gasoline?

    Science.gov (United States)

    2010-07-01

    ... gasoline? 80.1236 Section 80.1236 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Benzene Gasoline Benzene Requirements § 80.1236 What requirements apply to California gasoline? (a) Definition. For purposes of this subpart...

  6. 40 CFR 80.845 - What requirements apply to California gasoline?

    Science.gov (United States)

    2010-07-01

    ... gasoline? 80.845 Section 80.845 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Toxics Gasoline Toxics Performance Requirements § 80.845 What requirements apply to California gasoline? (a) Definition. For purposes of this...

  7. 22 CFR 225.101 - To what does this policy apply?

    Science.gov (United States)

    2010-04-01

    ... instructional strategies, or (ii) research on the effectiveness of or the comparison among instructional techniques, curricula, or classroom management methods. (2) Research involving the use of educational tests... applies to all research involving human subjects conducted, supported or otherwise subject to regulation...

  8. 49 CFR 11.101 - To what does this policy apply?

    Science.gov (United States)

    2010-10-01

    ... strategies, or (ii) research on the effectiveness of or the comparison among instructional techniques, curricula, or classroom management methods. (2) Research involving the use of educational tests (cognitive... applies to all research involving human subjects conducted, supported or otherwise subject to regulation...

  9. 21 CFR 1.240 - What other registration requirements apply?

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false What other registration requirements apply? 1.240 Section 1.240 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL GENERAL ENFORCEMENT REGULATIONS Registration of Food Facilities Additional Provisions § 1.240 What other...

  10. 45 CFR 400.145 - Opportunity to apply for services.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Opportunity to apply for services. 400.145 Section 400.145 Public Welfare Regulations Relating to Public Welfare OFFICE OF REFUGEE RESETTLEMENT, ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES REFUGEE RESETTLEMENT PROGRAM Refugee Social Services Applications,...

  11. 40 CFR 1051.1 - Does this part apply for my vehicles or engines?

    Science.gov (United States)

    2010-07-01

    ... (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM RECREATIONAL ENGINES AND VEHICLES Overview and Applicability § 1051.1 Does this part apply for my vehicles or engines? (a) The regulations in this part 1051... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Does this part apply for my vehicles...

  12. SOR/88-144, Atomic Energy Control Regulations, amendment

    International Nuclear Information System (INIS)

    1988-01-01

    These amendments dated 25 February 1988 mainly concern naturally-occurring radioactive prescribed substances (namely, uranium, thorium, radium, etc.). Any naturally-occurring radioactive material in a mineral or other material which has not been related to an activity associated with the development, application or use of atomic energy, is exempted from the scope of the Regulations. The Regulations will therefore not apply to such radioactive substances present in building materials or in minerals commonly used in industrial activities which are not associated with the nuclear fuel cycle. This exemption does not apply to such material in connection with import control and preparation for transport. (NEA)

  13. The application of dangerous goods regulations to the transport of radioactive wastes

    International Nuclear Information System (INIS)

    Blenkin, J.J.; Darby, W.P.; Heywood, J.D.; Wikinson, H.L.; Carrington, C.K.; Murray, M.A.

    1998-01-01

    Some radioactive materials to be transported, including certain radioactive wastes, contain materials that qualify as dangerous goods as defined by the United Nations Recommendations on the Transport of Dangerous Goods (United Nations 1997). The regulations governing the transport of radioactive and dangerous goods in the UK are largely based on the IAEA Regulations for the Safe Transport of Radioactive Material (IAEA 1990) and the UN Recommendations (United Nations 1993). Additional legislation will also apply including the Carriage of Dangerous Goods by Road (Driver Training) Regulations 1996 (UK 1996). The IAEA Transport Regulations are clear that where radioactive materials have other dangerous properties the requirements of other relevant transport regulations for dangerous goods must also be met. They require that consignments are appropriately segregated from other dangerous goods, in accordance with relevant legislation, and that dangerous properties such as explosiveness, flammability etc. are taken into account in packing, labelling, marking, placarding, storage and transport. In practice, however, it requires a clear understanding of the relationship between the IAEA Transport Regulations and other dangerous goods legislation in order to avoid a number of problems in the approval of package design. This paper discusses the regulations applying to the transport of dangerous goods and explores practical problems associated with implementing them. It highlights a number of opportunities for developing the regulations, to make them easier to apply to radioactive materials that also have other potentially dangerous properties. (authors)

  14. The C-terminal extension of human RTEL1, mutated in Hoyeraal-Hreidarsson syndrome, contains harmonin-N-like domains.

    Science.gov (United States)

    Faure, Guilhem; Revy, Patrick; Schertzer, Michael; Londono-Vallejo, Arturo; Callebaut, Isabelle

    2014-06-01

    Several studies have recently shown that germline mutations in RTEL1, an essential DNA helicase involved in telomere regulation and DNA repair, cause Hoyeraal-Hreidarsson syndrome (HHS), a severe form of dyskeratosis congenita. Using original new softwares, facilitating the delineation of the different domains of the protein and the identification of remote relationships for orphan domains, we outline here that the C-terminal extension of RTEL1, downstream of its catalytic domain and including several HHS-associated mutations, contains a yet unidentified tandem of harmonin-N-like domains, which may serve as a hub for partner interaction. This finding highlights the potential critical role of this region for the function of RTEL1 and gives insights into the impact that the identified mutations would have on the structure and function of these domains. © 2013 Wiley Periodicals, Inc.

  15. Rethinking regulations for disposal criticality

    International Nuclear Information System (INIS)

    Scott, M.; Doering, T.

    1997-01-01

    This paper provides the basis for the position that the current U.S. Nuclear Regulatory Commission (NRC) criticality regulation is in need of revision to address problems in implementing it for the postclosure period in a geologic high-level waste repository. The authors believe that the applicant for such a facility should be able to demonstrate that postulated postclosure criticality events will not cause unacceptable risk of deleterious effects on public health and safety. In addition, the applicant should be expected to take practical and feasible measures to reduce the probability of a criticality occurring, even if (as expected) the consequences of such a criticality for repository performance and public health and safety would be negligible. This approach, while recognizing the probabilistic nature of analyses of events and conditions in the distant future, is also arguably consistent with the defense in depth concept that has been successfully applied to nuclear reactor regulation. The authors believe regulations for postclosure criticality control should support this dual approach, rather than require a deterministic prohibition of criticality as does the current rule. The existing rule seems appropriate for the preclosure period, as long as it is clearly specified to apply only to that period

  16. 34 CFR 400.1 - What is the purpose of the Vocational and Applied Technology Education Programs?

    Science.gov (United States)

    2010-07-01

    ... Technology Education Programs? 400.1 Section 400.1 Education Regulations of the Offices of the Department of... APPLIED TECHNOLOGY EDUCATION PROGRAMS-GENERAL PROVISIONS § 400.1 What is the purpose of the Vocational and Applied Technology Education Programs? (a) The purpose of the Vocational and Applied Technology Education...

  17. Regulation of maize kernel weight and carbohydrate metabolism by abscisic acid applied at the early and middle post-pollination stages in vitro.

    Science.gov (United States)

    Zhang, Li; Li, Xu-Hui; Gao, Zhen; Shen, Si; Liang, Xiao-Gui; Zhao, Xue; Lin, Shan; Zhou, Shun-Li

    2017-09-01

    Abscisic acid (ABA) accumulates in plants under drought stress, but views on the role of ABA in kernel formation and abortion are not unified. The response of the developing maize kernel to exogenous ABA was investigated by excising kernels from cob sections at four days after pollination and culturing in vitro with different concentrations of ABA (0, 5, 10, 100μM). When ABA was applied at the early post-pollination stage (EPPS), significant weight loss was observed at high ABA concentration (100μM), which could be attributed to jointly affected sink capacity and activity. Endosperm cells and starch granules were decreased significantly with high concentration, and ABA inhibited the activities of soluble acid invertase and acid cell wall invertase, together with earlier attainment of peak values. When ABA was applied at the middle post-pollination stage (MPPS), kernel weight was observably reduced with high concentration and mildly increased with low concentration, which was regulated due to sink activity. The inhibitory effect of high concentration and the mild stimulatory effect of low concentration on sucrose synthase and starch synthase activities were noted, but a peak level of ADP-glucose pyrophosphorylase (AGPase) was stimulated in all ABA treatments. Interestingly, AGPase peak values were advanced by low concentration and postponed by high concentration. In addition, compared with the control, the weight of low ABA concentration treatments were not statistically significant at the two stages, whereas weight loss from high concentration applied at EPPS was considerably obvious compared with that of the MPPS, but neither led to kernel abortion. The temporal- and dose-dependent impacts of ABA reveal a complex process of maize kernel growth and development. Copyright © 2017 Elsevier GmbH. All rights reserved.

  18. Sor/88-114, 25 February 1988, Atomic Energy Control Regulations, amendment

    International Nuclear Information System (INIS)

    1988-01-01

    The amendments to the Regulations mainly concern naturally-occurring radioactive prescribed substances (namely, uranium, thorium, radium, etc.). Any naturally-occurring radioactive material in a mineral or other material which has not been related to an activity associated with the development, application or use of atomic energy, is exempted from the scope of the Regulations. The Regulations will therefore not apply to radioactive substances such as uranium or thorium present in building materials or in minerals commonly used in industrial activities which are not associated with the nuclear fuel cycle. This exemption does not apply to such material in connection with import control and preparation for transport [fr

  19. 45 CFR 400.312 - Opportunity to apply for services.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Opportunity to apply for services. 400.312 Section 400.312 Public Welfare Regulations Relating to Public Welfare OFFICE OF REFUGEE RESETTLEMENT, ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES REFUGEE RESETTLEMENT PROGRAM Targeted Assistance § 400.312 Opportunity t...

  20. Special feature article. Nuclear new age. Towards reform of laws and regulations

    International Nuclear Information System (INIS)

    Madarame, Haruki; Morokuzu, Muneo; Shiroyama, Hideaki; Nishiwaki, Yoshihiro; Marumo, Syunji; Suzuki, Takahiro; Hariyama, Hideo

    2007-01-01

    Since about half a century passes after the peaceful use of nuclear energy began in Japan, the safety laws and regulations of the nuclear energy becomes difficult to cope enough with the current situation without regulation structure changing. In March 2007, Tokyo University set up nuclear energy legislation study meeting' consisting of members from regulatory bodies, electric utilities, nuclear industries and others. The special feature introduces five opinions obtained through the argument in the meeting. As an example, Law for the Regulations of Nuclear Sources Material, Nuclear Fuel Material and Reactors is applied to basic design about the commercial reactors, but Electric Utilities Industry Law is applied to a detailed design, and different licensing standard is applied in each. Taking the adjustment of licensing standard with unifying these is necessary for efficiency. In addition, current law for the Regulations of Nuclear Sources Material, Nuclear Fuel Material and Reactors regulates according to the businesses such as reactor facilities, fuel fabrication plants and radioactive waste disposal. As for plural businesses, a low procedure and safety measures are demanded every each business. It is also necessary to include structure of the comprehensive licensing that assumed an enterprise running plural businesses. (T. Tanaka)

  1. REGULATIONS ON PHOTOVOLTAIC MODULE DISPOSAL AND RECYCLING.

    Energy Technology Data Exchange (ETDEWEB)

    FTHENAKIS,V.

    2001-01-29

    Environmental regulations can have a significant impact on product use, disposal, and recycling. This report summarizes the basic aspects of current federal, state and international regulations which apply to end-of-life photovoltaic (PV) modules and PV manufacturing scrap destined for disposal or recycling. It also discusses proposed regulations for electronics that may set the ground of what is to be expected in this area in the near future. In the US, several states have started programs to support the recycling of electronic equipment, and materials destined for recycling often are excepted from solid waste regulations during the collection, transfer, storage and processing stages. California regulations are described separately because they are different from those of most other states. International agreements on the movement of waste between different countries may pose barriers to cross-border shipments. Currently waste moves freely among country members of the Organization of Economic Cooperation and Development (OECD), and between the US and the four countries with which the US has bilateral agreements. However, it is expected, that the US will adopt the rules of the Basel Convention (an agreement which currently applies to 128 countries but not the US) and that the Convection's waste classification system will influence the current OECD waste-handling system. Some countries adopting the Basel Convention consider end-of-life electronics to be hazardous waste, whereas the OECD countries consider them to be non-hazardous. Also, waste management regulations potentially affecting electronics in Germany and Japan are mentioned in this report.

  2. 5 CFR 591.226 - How does OPM apply the CPIs?

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false How does OPM apply the CPIs? 591.226 Section 591.226 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS ALLOWANCES AND DIFFERENTIALS Cost-of-Living Allowance and Post Differential-Nonforeign Areas Cost-Of-Living...

  3. Panel presentation: Should some type of incentive regulation replace traditional methods for regulating LDC's?

    International Nuclear Information System (INIS)

    Farman, R.D.

    1992-01-01

    This paper discusses the wants and fears of gas utility companies with regards to incentive regulation. The idea of replacing the traditional rate-of-return regulation with incentive regulation sound very desirous in that it should provide greater management flexibility, quicker and more streamlined regulatory processes, and utility financial rewards based on how well customer needs are met. However, the main fear is that this could result in arbitrary, inappropriate productivity or efficiency targets, or would embody a risk/reward ratio skewed more heavily toward financial penalties than opportunities to increase earnings. The paper presents some of the obstacles of traditional regulation which include a lack of incentive to minimize operational costs; a lack of incentive to introduce new technology, products, or services; prevent the need for flexibility to compete in contestable markets; and the diversion caused by utility managers having to manage the regulatory process rather than delivering value to customers. The paper concludes by comparing the incentive regulation program used in the telecommunications industry to the natural gas industry to demonstrate why the success of the telecommunications model doesn't apply to the gas utilities incentive model

  4. 36 CFR 1220.18 - What definitions apply to the regulations in subchapter B?

    Science.gov (United States)

    2010-07-01

    ... RECORDS ADMINISTRATION RECORDS MANAGEMENT FEDERAL RECORDS; GENERAL § 1220.18 What definitions apply to the... for documentary materials in all physical forms, record and nonrecord, created by a Federal agency or... schedule. Documentary materials is a collective term that refers to recorded information, regardless of the...

  5. 24 CFR 1000.46 - Do drug-free workplace requirements apply?

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Do drug-free workplace requirements apply? 1000.46 Section 1000.46 Housing and Urban Development Regulations Relating to Housing and Urban... URBAN DEVELOPMENT NATIVE AMERICAN HOUSING ACTIVITIES General § 1000.46 Do drug-free workplace...

  6. 31 CFR 205.2 - What definitions apply to this part?

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false What definitions apply to this part? 205.2 Section 205.2 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE RULES AND PROCEDURES FOR...

  7. Regulation of alcohol advertising: Policy options for Australia

    Directory of Open Access Journals (Sweden)

    Sandra C. Jones

    2013-06-01

    Full Text Available A systematic search of academic databases was conducted to identify all refereed papers published between 1990 and 2012 on the regulation of alcohol advertising in Australia and three comparison countries (New Zealand, Canada and the UK. This paper reviews the codes that apply to alcohol advertising in each of the four countries, research into the effectiveness of these codes, and the small body of research into consumer attitudes towards alcohol advertising regulation. This review adduces considerable evidence that alcohol advertising influences drinking behaviours, and that current regulatory systems based on co-regulation and voluntary regulation (as is the case in Australia are ineffective. Recommendations are provided regarding the three pillars of regulation: volume restrictions, content restrictions, and infrastructure to support the regulatory environment.

  8. OSHA regulations: how they relate to ophthalmic practice.

    Science.gov (United States)

    Garber, N

    1992-01-01

    The OSHA regulations, which took effect March 6, 1992, require that all employees be trained in infection control practices when they are hired, their job description changes, or the standards for universal precautions are revised. An explanation, provided to inform employees where a copy of the OSHA standard can be reviewed should be available at each clinical and surgical site, and OSHA regulation definitions must also be posted. The OSHA regulation applies to any clinical, housekeeping, or administrative staff that has any potential risk of exposure to blood or other potentially infectious substances.

  9. Work place regulations - effects on power station construction

    International Nuclear Information System (INIS)

    Richter, E.

    1979-01-01

    The paper describes that the Workplace Order and Workplace Regulations cannot be applied in every area of a conventional power station or the conventional sections of nuclear power stations. In any case extensive regulations already exist for the hot regions of nuclear power stations. A proposal is made as to which areas of power stations should be developed in accordance with the Workplace Order and the Workplace Regulations and which areas are not deemed to be 'Workplaces'. This is illustrated with the aid of typical examples. (orig.) [de

  10. Epidemiology applied to health physics

    International Nuclear Information System (INIS)

    1983-01-01

    The technical program of the mid-year meeting of the Health Physics Society, entitled Epidemiology Applied to Health physics, was developed to meet three objectives: (1) give health physicists a deeper understanding of the basics of epidemiological methods and their use in developing standards, regulations, and criteria and in risk assessment; (2) present current reports on recently completed or on-going epidemiology studies; and (3) encourage greater interaction between the health physics and epidemiology disciplines. Included are studies relating methods in epidemiology to radiation protection standards, risk assessment from exposure to bone-seekers, from occupational exposures in mines, mills and nuclear facilities, and from radioactivity in building materials

  11. 41 CFR 102-118.35 - What definitions apply to this part?

    Science.gov (United States)

    2010-07-01

    ... PAYMENT AND AUDIT General Definitions § 102-118.35 What definitions apply to this part? The following... terms and conditions of a contract in electronic communication. Electronic commerce means electronic... 10721), or other equivalent contract, arrangement or exemption from regulation. Postpayment audit means...

  12. A quantitative model of regulator's preference factor (RPF) in electricity-environment coordinated regulation system

    Energy Technology Data Exchange (ETDEWEB)

    Ren, Yulong; Fu, Shijun [Economy and Business Administration School of Chongqing University, Chongqing 400030 (China)

    2010-12-15

    This paper explores quantification of regulator's preference factor (RPF) in electricity-environment coordinated regulation system. Based on social welfare economics, we articulately depict RPF's qualitative concept and its economic meaning. Then, applying abstract functions (i.e., abstract social welfare function, abstract utility function, and abstract production function), we deduce the partial-social-welfare elasticity, and build the mathematics model of maximizing social welfare. We nest this elasticity into the model's Kuhn-Tucker conditions, and obtain RPF's definition formula. By solving the Kuhn-Tucker conditions, we get RPF's quantitative formula, which solves the problem of hard to quantify regulator's preference in electricity-environment coordinated regulation system. The result shows that RPF only has relationship to subsystems' production function, and is independent of social welfare function and subsystems' utility function. Finally, we provide an empirical research based on the western region of China from year 1995 to 2004. It reveals that regulator has relative stability preference to mitigating pollutants. And validity test confirms that the empirical result is fit well to the practice. The RPF is truly a more general and valid instrument to measure regulator's preference in its regulated field. (author)

  13. Regulate or deregulate. Influencing network interconnection charges

    Energy Technology Data Exchange (ETDEWEB)

    Van De Wielle, B.

    2003-06-01

    We study the choice between regulating interconnection charges or delegating their determination to the operators, both in a non-mature and a mature market. Three regulatory regimes are considered: full, cost-based and bill-and-keep. Delegation corresponds to bargaining about the interconnection charges using the regulatory schemes as disagreement outcomes. Applying regulation benefits the consumers. Under full regulation, access charges account for asymmetries and allow a unique Ramsey price. Delegation benefits the operators. In a mature market delegation robs the government of any market influence. In a non-mature market government preferences coincide with those of the largest operator and are disadvantageous for entry.

  14. Some regulation aspects in dismantling

    International Nuclear Information System (INIS)

    Niel, J.C.

    1993-01-01

    In the French regulation framework, operations linked to dismantling are controlled by an overall technical and legislative system applied to all the different stages of the facility (commissioning, etc.). Government control on facilities under dismantling is aimed at dismantling operation safety and security, and dismantling waste processing in order to ensure public and environmental protection

  15. 40 CFR 52.2731 - Control strategy and regulations: Sulfur oxides.

    Science.gov (United States)

    2010-07-01

    ... for Control of Atmospheric Pollution, as it applies to those areas listed in paragraph (a) of this... of the Puerto Rico Regulation for Control of Atmospheric Pollution would permit the use of stack... of Article 6 of the Puerto Rico Regulation for Control of Atmospheric Pollution is disapproved to the...

  16. 45 CFR 400.50 - Opportunity to apply for cash assistance.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Opportunity to apply for cash assistance. 400.50 Section 400.50 Public Welfare Regulations Relating to Public Welfare OFFICE OF REFUGEE RESETTLEMENT, ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES REFUGEE RESETTLEMENT PROGRAM Refugee Cash Assistance § 400.50...

  17. Increased risk of ischemic stroke after hyperosmolar hyperglycemic state: a population-based follow-up study.

    Directory of Open Access Journals (Sweden)

    Jen-Yu Wang

    Full Text Available BACKGROUND: Although much attention has been focused on the association between chronic hyperglycemia and cerebrovascular diseases in type 2 diabetes mellitus (DM patients, there is no data regarding the risk of ischemic stroke after a hyperosmolar hyperglycemic state (HHS attack. The objective of this study was to investigate the risk of ischemic stroke in type 2 DM patients after an HHS attack. METHODS: From 2004 to 2008, this retrospective observational study was conducted on a large cohort of Taiwanese using Taiwan's National Health Insurance Research Database (NHIRD. We identified 19,031 type 2 DM patients who were discharged with a diagnosis of HHS and 521,229 type 2 DM patients without an HHS diagnosis. Using the propensity score generated from logistic regression models, conditional on baseline covariates, we matched 19,031 type 2 DM patients with an HHS diagnosis with the same number from the comparison cohort. The one-year cumulative rate for ischemic stroke was estimated using the Kaplan-Meier method. After adjusting covariates, Cox proportional hazard regression was used to compute the adjusted one-year rate of ischemic stroke. RESULTS: Of the patients sampled, 1,810 (9.5% of the type 2 DM patients with HHS and 996 (5.2% of the comparison cohort developed ischemic stroke during the one-year follow-up period. After adjusting for covariates, the adjusted HR for developing ischemic stroke during the one-year follow-up period was 1.8 (95% C.I., 1.67 to 1.95, P<0.001 for type 2 DM patients with HHS compared with those without HHS. CONCLUSION: Although DM is a well-recognized risk factor for atherosclerosis, type 2 DM patients that have suffered a HHS attacks are at an increased risk of developing ischemic stroke compared with those without HHS.

  18. Hot-spot analysis applied to the identification of potential high and low regulating, providing and cultural ecosystem services in Vilnius Region (Lithuania)

    Science.gov (United States)

    Pereira, Paulo; Daniel, Depellegrin; Egarter-Vigl, Lukas; Cerda, Artemi; Estebaranz, Ferran; Misiune, Ieva

    2017-04-01

    Ecosystem services (ES) potential assessment is crucial for a correct territorial planning at different scales of analysis (Depellegrin et al., 2016). In urban and peri-urban areas, sprawl, grazing and unsustainable agriculture practices contributed to land degradation and de decrease of the quality and quantity of the services provided by these areas (Eldridge and Delgado-Baquerizo, 2017; Favretto et al., 2017). In order to understand the spatial pattern of these impacts, mapping ES potential is key to understand the areas that need to be restored and protected for an unsustainable use (Brevik et al., 2016; Egarter-Vigl et al., 2017; Pereira et al., 2017). Hot-spot analysis is a good method to identify clusters of areas with high and low capacity for ES capacity. This analysis is very useful to detect homogeneous areas, where ES have high or low quality. The objective of this work is to apply a hot-spot analysis to detect areas with high/low capacity for Regulating, Provision, Cultural and Total ES in Vilnius region. ES potential was carried out based on the matrix developed by Burkhard et al. (2009), which ranks ES capacity from 0= no capacity to 5=very high relevant capacity to a different land use type. The results showed that regulating, providing and cultural and total ES have a significant dispersed (low-clustered) pattern: Regulating (Z-score=-19.28, pInternational Journal of Sustainable Development and World Ecology, 23, 441-455. Egarter-Vigl, L., Depellegrin, D., Pereira, P., De Groot, D., Tappeiner, U. (2017) Mapping the ecosystem service delivery chain: Capacity, flow, and demand pertaining to aesthetic experiences in mountain landscapes, Science of the Total Environment, 574, 442-436. Eldridge, D.J., Delgado-Baquerizo, M. (2017) Continental-scale impacts of livestock grazing on ecosystem supporting and regulating services. Land Degradation and Development. DOI: 10.1002/ldr.2668 Favretto, N., Lueding, E., Stringer, L., Dougill, A.J. (2017) Valuing

  19. Conceptual frameworks of the notification, registration and licensing system applied in Cuba

    International Nuclear Information System (INIS)

    Jerez Verqueria, Pablo; Quevedo Garcia, Jose R.; Betancourt Hernadez, Luisa A.

    1996-01-01

    In our country, a safety regulations has been established whose objective is to establish the authorization system to apply and the requirements to fulfill by the license applications. The present work describes how such system has been conceptually conceived

  20. Federal approaches to the regulation of noncigarette tobacco products.

    Science.gov (United States)

    Freiberg, Michael J A

    2012-11-01

    Under a grant funded by ClearWay Minnesota(SM) and in partnership with nationally recognized experts in tobacco product regulation, the Public Health Law Center investigated how laws at every level apply, or fail to apply, to noncigarette tobacco products--also called "other tobacco products." During the years 2010-2011, standard legal research techniques were used to identify and compile relevant statutes, regulations, decisions, pleadings, proposals, and related materials. Sources included standard commercial legal databases such as LexisNexis and Westlaw, online sources for pending rules and legislation, and direct contact with courts for legal pleadings and unpublished decisions. These legal authorities related to many aspects of the regulation, including price, flavorants, youth access, marketing restrictions, and product design of other tobacco products. Five of these products were used as case studies: dissolvable tobacco products, electronic cigarettes, little cigars, snus, and water pipes. Research during the years 2010-2011 revealed that the federal regulation of other tobacco products lags behind the regulation of more "traditional" tobacco products, such as cigarettes and moist snuff. Federal regulatory options to expand regulation of these products were identified. The article highlights several federal policy interventions that would address gaps in the regulation of other tobacco products. The FDA must determine whether these interventions will benefit public health and, if so, to what extent--the legal criteria for intervention under the federal Family Smoking Prevention and Tobacco Control Act. Copyright © 2012 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

  1. Intraocular pressure reduction and regulation system

    Science.gov (United States)

    Baehr, E. F.; Burnett, J. E.; Felder, S. F.; Mcgannon, W. J.

    1979-01-01

    An intraocular pressure reduction and regulation system is described and data are presented covering performance in: (1) reducing intraocular pressure to a preselected value, (2) maintaining a set minimum intraocular pressure, and (3) reducing the dynamic increases in intraocular pressure resulting from external loads applied to the eye.

  2. 78 FR 36723 - Federal Management Regulation (FMR); Restrictions on International Transportation of Freight and...

    Science.gov (United States)

    2013-06-19

    ..., Sequence 1] RIN 3090-AJ34 Federal Management Regulation (FMR); Restrictions on International Transportation... Administration (GSA). ACTION: Proposed rule. SUMMARY: GSA is proposing to amend the Federal Management Regulation... Federal Management Regulation (FMR) to state clearly that this part applies to all agencies and wholly...

  3. Comparison between the Harris- and Oxford Hip Score to evaluate outcomes one-year after total hip arthroplasty

    NARCIS (Netherlands)

    Weel, Hanneke; Lindeboom, Robert; Kuipers, Sander E.; Vervest, Ton M. J. S.

    2017-01-01

    Harris Hip Score (HHS) is a surgeon administered measurement for assessing hip function before and after total hip arthroplasties (THA). Patient reported outcome measurements (PROMs) such as the Oxford Hip Score (OHS) are increasingly used. HHS was compaired to the OHS assessing whether the HHS can

  4. Guide to Radiation Safety regulations and guidelines (SSMFS 2012:3) on the management of contaminated ash

    International Nuclear Information System (INIS)

    Moere, Hans

    2012-06-01

    Energy producers burning peat or wood fuel can obtain ash that is contaminated with cesium-137 from Tjernobyl accident or naturally occurring uranium, thorium and potassium, from some peat bogs. Regulations (SSMFS 2012:3) have been developed which regulates how the contaminated ash should be handled. The regulations affect all who handle contaminated ash in incinerators, landfills, public works, ash recycling, transportation or recycling of ash in other ways. Radiation Safety regulations and guidelines (SSMFS 2012:3) on the management of contaminated ash will apply from 1 September 2012. At that time Regulations (SSMFS 2008:16) on the management of ash that is contaminated with cesium-137, ceases to apply. The contents have been incorporated into the new regulations. This report provides explanations and guidance to the Regulations in order to facilitate the practical application. This guidance is not legally binding

  5. The Swedish Nuclear Power Inspectorate's Regulations concerning Safety in connection with the Disposal of Nuclear Material and Nuclear Waste. General Recommendations concerning the Application of the Swedish Nuclear Power Inspectorate's Regulations above

    International Nuclear Information System (INIS)

    2002-06-01

    An english translation of the original Swedish regulations concerning the safety in disposal of nuclear wastes is published in this booklet, together with recommendations on how these regulations can be applied

  6. Complex fluids with mobile charge-regulating macro-ions

    Science.gov (United States)

    Markovich, Tomer; Andelman, David; Podgornik, Rudi

    2017-10-01

    We generalize the concept of charge regulation of ionic solutions, and apply it to complex fluids with mobile macro-ions having internal non-electrostatic degrees of freedom. The suggested framework provides a convenient tool for investigating systems where mobile macro-ions can self-regulate their charge (e.g., proteins). We show that even within a simplified charge-regulation model, the charge dissociation equilibrium results in different and notable properties. Consequences of the charge regulation include a positional dependence of the effective charge of the macro-ions, a non-monotonic dependence of the effective Debye screening length on the concentration of the monovalent salt, a modification of the electric double-layer structure, and buffering by the macro-ions of the background electrolyte.

  7. cDREM: inferring dynamic combinatorial gene regulation.

    Science.gov (United States)

    Wise, Aaron; Bar-Joseph, Ziv

    2015-04-01

    Genes are often combinatorially regulated by multiple transcription factors (TFs). Such combinatorial regulation plays an important role in development and facilitates the ability of cells to respond to different stresses. While a number of approaches have utilized sequence and ChIP-based datasets to study combinational regulation, these have often ignored the combinational logic and the dynamics associated with such regulation. Here we present cDREM, a new method for reconstructing dynamic models of combinatorial regulation. cDREM integrates time series gene expression data with (static) protein interaction data. The method is based on a hidden Markov model and utilizes the sparse group Lasso to identify small subsets of combinatorially active TFs, their time of activation, and the logical function they implement. We tested cDREM on yeast and human data sets. Using yeast we show that the predicted combinatorial sets agree with other high throughput genomic datasets and improve upon prior methods developed to infer combinatorial regulation. Applying cDREM to study human response to flu, we were able to identify several combinatorial TF sets, some of which were known to regulate immune response while others represent novel combinations of important TFs.

  8. On the Regulation of Life Safety Risk

    DEFF Research Database (Denmark)

    Faber, Michael Havbro; Sørensen, John Dalsgaard; Vrouwenvelder, A.C.W.M.

    2015-01-01

    . Starting point is taken in a short outline of what is considered to comprise the present best practice rationale for life safety and health risk regulation. Thereafter, based on selected principal examples from different application areas, inconsistencies in present best practice risk quantification...... absolute level of individual life safety risk subject to assessment of acceptability. It is highlighted that a major cause of inconsistency in risk quantifications and comparisons originates from the fact that present regulations partly address societal activities and partly address applied technologies...

  9. 78 FR 16857 - Office of the Assistant Secretary for Financial Resources, Office of Grants and Acquisition...

    Science.gov (United States)

    2013-03-19

    ... Inventory.'' The following should be changed: The notice provided an incorrect URL address: http://www.hhs.gov/grants/servicecontractsfy11.html . The correct URL address is as follows: http://www.hhs.gov... following URL address: http://www.hhs.gov/grants/servicecontractsfy11.html . Change the fiscal year to FY...

  10. Regulations for the safe transport of radioactive materials. 1973 rev. ed

    International Nuclear Information System (INIS)

    1973-01-01

    The purpose of these Regulations is to establish standards of safety which provide an acceptable level of control of the radiation hazards to persons, property and the environment that are associated with the transport of radioactive material. These Regulations shall apply to the transport by land, water or air, including transport on own account, of radioactive material other than that which is an integral part of the means of transport. Transport shall be deemed to include any operation incidental to the whole course of carriage, such as loading, unloading and storage in transit. The term includes both normal transport and that under accident conditions. These Regulations do not apply within establishments where the radioactive material is produced, used or stored, other than in the course of transport, and in respect of which other appropriate safety regulations are in force. In the transport of radioactive materials, any other hazardous characteristics of these materials such as explosiveness, inflammability, pyrophoricity, chemical toxicity, and corrosiveness must be taken into account in such a manner as to be in compliance with the relevant transport regulations for dangerous goods of each of the countries through or into which the materials will be transported, as well as in compliance with these Regulations.

  11. 21 CFR 1.403 - What requirements apply to an informal hearing?

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false What requirements apply to an informal hearing? 1.403 Section 1.403 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL GENERAL ENFORCEMENT REGULATIONS Administrative Detention of Food for Human or Animal Consumption...

  12. 76 FR 14017 - Call for Comments on the Draft Report of the Adult Immunization Working Group to the National...

    Science.gov (United States)

    2011-03-15

    ... and recommendations could be found on the Web at http://www.hhs.gov/nvpo/nvac/subgroups/adultimmunization . The Web address where the draft report and recommendations can be found is http://www.hhs.gov...) The draft report and recommendations are available on the Web at http://www.hhs.gov/nvpo/nvac...

  13. Self-Regulation Competence in Music Education

    Science.gov (United States)

    Ludovico, Luca Andrea; Mangione, Giuseppina Rita

    2014-01-01

    This work starts from a systematic review about music education and self-regulation during learning processes. Then the paper identifies those meta-cognitive strategies that music students should adopt during their instrumental practice. The goal is applying such concepts in order to rethink the structure of a didactic e-book for instrumental…

  14. 34 CFR 658.4 - What definitions apply to the Undergraduate International Studies and Foreign Language Program?

    Science.gov (United States)

    2010-07-01

    ... International Studies and Foreign Language Program? 658.4 Section 658.4 Education Regulations of the Offices of... UNDERGRADUATE INTERNATIONAL STUDIES AND FOREIGN LANGUAGE PROGRAM General § 658.4 What definitions apply to the Undergraduate International Studies and Foreign Language Program? The definitions in 34 CFR 655.4 apply to this...

  15. Long-term follow-up of hypothenar hammer syndrome: a series of 47 patients.

    Science.gov (United States)

    Marie, Isabelle; Hervé, Fabien; Primard, Etienne; Cailleux, Nicole; Levesque, Hervé

    2007-11-01

    Hypothenar hammer syndrome (HHS) is an uncommon form of secondary Raynaud phenomenon, occurring mainly in subjects who use the hypothenar part of the hand as a hammer; the hook of the hamate strikes the superficial palmar branch of the ulnar artery in the Guyon space, leading to occlusion and/or aneurysm of the ulnar artery. In patients with HHS, such injuries of the palmar ulnar artery may lead to severe vascular insufficiency in the hand with occlusion of digital artery. To date, only a few series have analyzed the long-term outcome of patients with HHS. This prompted us to conduct the current retrospective study to 1) evaluate the prevalence of HHS in patients with Raynaud phenomenon and 2) assess the short-term and long-term outcome in patients with HHS. From 1990 to 2006, 4148 consecutive patients were referred to the Department of Internal Medicine at the University of Rouen medical center for evaluation of Raynaud phenomenon using nailfold capillaroscopy. HHS was diagnosed in 47 of these 4148 patients (1.13% of cases).Forty-three patients (91.5%) had occupational exposure to repetitive palmar trauma. The more common occupations were factory worker (21.3%), mason (12.8%), carpenter (10.6%), and metal worker (10.6%); the mean duration of occupational exposure to repetitive palmar trauma at HHS diagnosis was 21 years. One patient (2.1%) had recreational exposure (aikido training) to repetitive trauma of the palmar ulnar artery, and 3 other patients (6.4%) developed HHS related to a single direct injury to the hypothenar area. Clinical manifestations were more often unilateral (87.2%) involving the dominant hand (93%). HHS complications included digital ischemic symptoms (ischemia: n = 21, necrosis: n = 20) and irritation of the sensory branch of the ulnar nerve (n = 11). In HHS patients, angiography demonstrated occlusion of the ulnar artery in the area of the Guyon space (59.6%), aneurysm of the ulnar artery in the area of the Guyon space (40.4%), and embolic

  16. Atomic Energy Control Regulations: interpretation of revisions relating to industrial radiography

    International Nuclear Information System (INIS)

    1983-09-01

    The purpose of this document is to provide assistance to those affected by section 18 to 18.23 of the Canadian Atomic Energy Control Regulations. Words, phrases, and concepts that are specific to these Regulations are explained herein. However, the corresponding sections of the Regulations should be examined to obtain the exact wording. Although sections 18 to 18.23 of the Canadian Atomic Energy Control Regulations apply to both neutron and gamma radiography, this guide has been written for only the latter. Persons engaged in neutron radiography should consult the Atomic Energy Control Board (AECB)

  17. Waste classification and methods applied to specific disposal sites

    International Nuclear Information System (INIS)

    Rogers, V.C.

    1979-01-01

    An adequate definition of the classes of radioactive wastes is necessary to regulating the disposal of radioactive wastes. A classification system is proposed in which wastes are classified according to characteristics relating to their disposal. Several specific sites are analyzed with the methodology in order to gain insights into the classification of radioactive wastes. Also presented is the analysis of ocean dumping as it applies to waste classification. 5 refs

  18. Development and action plan for the alternative regulation instruments

    International Nuclear Information System (INIS)

    Kim, Jung Yul; Hagm, Yo Sang

    2004-02-01

    The goal of this study to provide highly practical model, needed for regulation if nuclear power safety to regulation agency. Since nuclear power safety regulation has different characteristics, compared to general regulation, it is important to have new point of view and approach. But application possibility for regulation that guarantees the 'perfect safety' is very low. Therefore, it is important establish nuclear power safety regulation that is realistic as well as safety securing. In order to establish high quality regulation, evaluation of existing regulation must be done first. Thus in this study, 6 standards to evaluate existing regulation are suggested. They are clearness, efficiency, flexibility, reliability, responsibility and political consideration. Also, strategies to complement the weak points of regulatory governance, regulatory sunset, regulatory map, regulatory negotiation, regulatory benefit-cost analysis, etc. These strategies can be applied all in one regulation, and can strategically be selected for application. After analyzing the result if case analysis on nuclear furnace regulation for research study, agreement was made that it is most efficient to consider in the order if clearness reliability, flexibility, confidence, political consideration, administrative efficiency and economic efficiency

  19. Development and action plan for the alternative regulation instruments

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jung Yul [Daegu Univ., Gyeongsan (Korea, Republic of); Hagm, Yo Sang [Korea Univ., Seoul (Korea, Republic of)

    2004-02-15

    The goal of this study to provide highly practical model, needed for regulation if nuclear power safety to regulation agency. Since nuclear power safety regulation has different characteristics, compared to general regulation, it is important to have new point of view and approach. But application possibility for regulation that guarantees the 'perfect safety' is very low. Therefore, it is important establish nuclear power safety regulation that is realistic as well as safety securing. In order to establish high quality regulation, evaluation of existing regulation must be done first. Thus in this study, 6 standards to evaluate existing regulation are suggested. They are clearness, efficiency, flexibility, reliability, responsibility and political consideration. Also, strategies to complement the weak points of regulatory governance, regulatory sunset, regulatory map, regulatory negotiation, regulatory benefit-cost analysis, etc. These strategies can be applied all in one regulation, and can strategically be selected for application. After analyzing the result if case analysis on nuclear furnace regulation for research study, agreement was made that it is most efficient to consider in the order if clearness reliability, flexibility, confidence, political consideration, administrative efficiency and economic efficiency.

  20. 40 CFR 80.583 - What alternative sampling and testing requirements apply to importers who transport motor vehicle...

    Science.gov (United States)

    2010-07-01

    ... requirements apply to importers who transport motor vehicle diesel fuel, NRLM diesel fuel, or ECA marine fuel... (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Motor Vehicle Diesel Fuel... alternative sampling and testing requirements apply to importers who transport motor vehicle diesel fuel, NRLM...

  1. Molecular imaging of transcriptional regulation during inflammation

    Directory of Open Access Journals (Sweden)

    Carlsen Harald

    2010-04-01

    Full Text Available Abstract Molecular imaging enables non-invasive visualization of the dynamics of molecular processes within living organisms in vivo. Different imaging modalities as MRI, SPECT, PET and optic imaging are used together with molecular probes specific for the biological process of interest. Molecular imaging of transcription factor activity is done in animal models and mostly in transgenic reporter mice, where the transgene essentially consists of a promoter that regulates a reporter gene. During inflammation, the transcription factor NF-κB is widely involved in orchestration and regulation of the immune system and almost all imaging studies in this field has revolved around the role and regulation of NF-κB. We here present a brief introduction to experimental use and design of transgenic reporter mice and a more extensive review of the various studies where molecular imaging of transcriptional regulation has been applied during inflammation.

  2. 45 CFR 660.6 - What procedures apply to the selection of programs and activities under these regulations?

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false What procedures apply to the selection of programs... Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION INTERGOVERNMENTAL REVIEW OF THE NATIONAL SCIENCE FOUNDATION PROGRAMS AND ACTIVITIES § 660.6 What procedures apply to the selection of programs and activities...

  3. HHS Enterprise Data Inventory

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Enterprise Data Inventory (EDI) is the comprehensive inventory listing of agency data resources including public, restricted public, and non-public datasets.

  4. Privatisation and regulation - the effect on the U.K. gas industry

    International Nuclear Information System (INIS)

    Price, C.

    1991-01-01

    The U.K. gas industry is a monopolist, privatised in 1986 and subject to partial regulation and general monopoly policy. From April 1992 a new regulatory regime will be applied. This paper explores the impact of privatisation and partial regulation in the gas industry during the first quinquennium and illustrates the issues for regulation and pricing where costs are common to regulated and unregulated sectors. Attributable costs of gas supply are derived and a 'marginal cost' based tariff suggested. This is used as a basis for examining the industry's pricing policy in its several markets, and to analyse its response to privatisation and the regulation it has experienced. (Author)

  5. 31 CFR 370.23 - What other requirements apply to a financial institution?

    Science.gov (United States)

    2010-07-01

    ... financial institution? 370.23 Section 370.23 Money and Finance: Treasury Regulations Relating to Money and... requirements apply to a financial institution? The financial institution warrants that it will comply with all requirements imposed upon Receiving Depository Financial Institutions under the Operating Rules of the National...

  6. Basis for applying for exemption according to species protection regulation. Final repository for spent nuclear fuel at Forsmark; Underlag till ansoekan om dispens enligt artskyddsfoerordningen. Slutfoervar foer anvaent kaernbraensle i Forsmark

    Energy Technology Data Exchange (ETDEWEB)

    2011-02-15

    SKB will submit applications for permits and admissibility under the Environmental Act and under the Nuclear Activities Act to construct and operate a disposal facility for spent nuclear fuel at Forsmark. In the final repository the spent nuclear fuel from Swedish nuclear power plants is placed in order to protect human health and the environment against harmful effects of ionizing radiation. Construction and operation of the disposal facility in Forsmark will make an impact, give effects and consequences for the natural environment. Utilization of land for the construction of the facility and the impact on ground water as a result of groundwater drainage is expected to have negative consequences for the species included in species protection regulation. Thus, the planned activity require exemption from species protection regulation (SFS 2007:845). The purpose of this document is to provide a basis for an application for exemption under 14 paragraph species protection regulation from the prohibitions of 4, 6, 7 and 8 paragraph species protection regulation. A basis for the exemption application is that the proposed activity is considered to have an 'overriding public interest' prescribed in 14 paragraph species protection regulation. The document reports the impact, effects and consequences of the planned activities on species covered in the species protection regulation. The impact on protected species can be divided into two categories: - Direct effects on protected species and their habitats by utilization of the land. - Indirect effects on protected species and their habitats in the drainage of groundwater and the effect on groundwater levels. The document also includes a description of planned actions to prevent, restrict and compensate for the effects and consequences that the activity may cause. By applying for an exemption under 14 paragraph species protection regulation in a separate order from the application for permit according to chapters 9

  7. Basis for applying for exemption according to species protection regulation. Final repository for spent nuclear fuel at Forsmark; Underlag till ansoekan om dispens enligt artskyddsfoerordningen. Slutfoervar foer anvaent kaernbraensle i Forsmark

    Energy Technology Data Exchange (ETDEWEB)

    2011-02-15

    SKB will submit applications for permits and admissibility under the Environmental Act and under the Nuclear Activities Act to construct and operate a disposal facility for spent nuclear fuel at Forsmark. In the final repository the spent nuclear fuel from Swedish nuclear power plants is placed in order to protect human health and the environment against harmful effects of ionizing radiation. Construction and operation of the disposal facility in Forsmark will make an impact, give effects and consequences for the natural environment. Utilization of land for the construction of the facility and the impact on ground water as a result of groundwater drainage is expected to have negative consequences for the species included in species protection regulation. Thus, the planned activity require exemption from species protection regulation (SFS 2007:845). The purpose of this document is to provide a basis for an application for exemption under 14 paragraph species protection regulation from the prohibitions of 4, 6, 7 and 8 paragraph species protection regulation. A basis for the exemption application is that the proposed activity is considered to have an 'overriding public interest' prescribed in 14 paragraph species protection regulation. The document reports the impact, effects and consequences of the planned activities on species covered in the species protection regulation. The impact on protected species can be divided into two categories: - Direct effects on protected species and their habitats by utilization of the land. - Indirect effects on protected species and their habitats in the drainage of groundwater and the effect on groundwater levels. The document also includes a description of planned actions to prevent, restrict and compensate for the effects and consequences that the activity may cause. By applying for an exemption under 14 paragraph species protection regulation in a separate order from the application for permit according to chapters 9 and 11

  8. Networks, complexity and internet regulation scale-free law

    OpenAIRE

    Guadamuz, Andres

    2013-01-01

    This book, then, starts with a general statement: that regulators should try, wherever possible, to use the physical methodological tools presently available in order to draft better legislation. While such an assertion may be applied to the law in general, this work will concentrate on the much narrower area of Internet regulation and the science of complex networks The Internet is the subject of this book not only because it is my main area of research, but also because –without...

  9. The innovation inducement impact of environmental regulations on maritime transport

    DEFF Research Database (Denmark)

    Makkonen, Teemu; Repka, Sari

    2016-01-01

    , contrasting views, arguing that environmental regulations will, in fact, enhance firms’ competitiveness by inducing innovation, have also been voiced. Here this issue is examined through a literature review on the innovation inducement impact of environmental regulations (i.e. the Porter Hypothesis......), in general, and the economic impacts of environmental regulations (here Annex VI of the MARPOL Convention) as it applies to shipping in Northern Europe, in particular. According to the review, the literature is still inconclusive and lacks a clear consensus on the economic and innovation inducement impacts......Maritime transport is facing wide-ranking challenges due to stricter environmental regulations. It has been positioned that these stricter environmental regulations will significantly hamper the competitiveness of the shipping industry and other export/import oriented industries. However...

  10. Regulating health: transcending disciplinary boundaries.

    Science.gov (United States)

    Seddon, Toby

    2013-03-01

    Health and health care problems can be addressed from multiple disciplinary perspectives. This raises challenges for how to do cross-disciplinary scholarship in ways that are still robust, rigorous and coherent. This paper sets out one particular approach to cross-cutting research--regulation--which has proved extremely fertile for scholars working in diverse fields, from coal mine safety to tax compliance. The first part of the paper considers how regulatory ideas might be applied to health and health care research in general. The second part goes on to sketch out how a regulation perspective on one specific area, illicit drug policy, can open up new directions for research. In conclusion, a future research agenda is outlined for regulatory scholarship on health and health care.

  11. 77 FR 31864 - Prospective Grant of Exclusive License: Development of PANVACTM

    Science.gov (United States)

    2012-05-30

    ... divisional applications claiming priority to this application; 7. Australia Patent No. 745863 [HHS Ref. No. E... and divisional applications; [HHS Ref. No. E-260-1994/2-JP-21, JP-25 and JP-26]; Australia Patent No... Patent Application No. 2,412,050 filed June 15, 2001 [HHS Ref. No. E-187-2000/0-CA-05]; Australia Patent...

  12. 24 CFR 1000.52 - What Indian preference requirements apply to IHBG procurement?

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false What Indian preference requirements apply to IHBG procurement? 1000.52 Section 1000.52 Housing and Urban Development Regulations Relating to..., DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT NATIVE AMERICAN HOUSING ACTIVITIES General § 1000.52 What Indian...

  13. Safety regulation KTA 3901: Communication systems for nuclear power plants

    International Nuclear Information System (INIS)

    1981-01-01

    The regulation applies to communication systems in stationary nuclear power plants with at least one power plant unit, i.e. alarm systems, staff locator systems, communicators, and systems for external communication. The regulation determines the type and extent of staff communication systems as well as the demands to be made on layout, installation, operating systems, and testing of communication systems for nuclear power plants. (orig./HP) [de

  14. Study on effects of environmental regulation on competitiveness

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Man Ok; Lim, Hyun Jeong [Korea Environment Institute, Seoul (Korea)

    1999-12-01

    For Korea, the claim that the enhancement of environmental regulation is worsening the international competitiveness of the business is dominant. However, it is too early to reestablish a relationship between environmental regulation and competitiveness with the above new aspect. In fact, the economic development, which is brought a quantitative growth, and the maintenance of environmental quality, which is brought a qualitative growth, are very important on decision making in economic and social policy. In this study, it represents the results of existing positive studies on the relationship between the enhancement of environmental regulation, trade and productivity. Moreover, the objective of this study is on applying it based on the data of Korea. 86 refs., 13 figs., 35 tabs.

  15. 45 CFR 2520.60 - What government-wide requirements apply to staff fundraising under my AmeriCorps grant?

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false What government-wide requirements apply to staff fundraising under my AmeriCorps grant? 2520.60 Section 2520.60 Public Welfare Regulations Relating to Public... C PROGRAMS § 2520.60 What government-wide requirements apply to staff fundraising under my Ameri...

  16. Regulating Direct-to-Consumer Advertising of Prescription Drugs in the Digital Age

    Directory of Open Access Journals (Sweden)

    Shannon Gibson

    2014-07-01

    Full Text Available The increasing prominence of new Internet and social media technologies and their growing importance as a source of health information are pushing the pharmaceutical industry towards digital channels. This paper explores the potential impacts of the pharmaceutical industry’s increasing interest in online marketing and considers how the existing regulatory framework in Canada translates into the social media sphere. Direct-to-consumer advertising (DTCA of prescription drugs is prohibited in Canada, as it is in most industrialized countries. Although Health Canada has reaffirmed that the existing DTCA regulations apply to new Internet and social media technologies, new dynamics such as user-generated content, consumer propagation, and targeted marketing make applying the existing regulations an uncertain process. Moreover, certain problems often associated with DTCA may be exacerbated in the social media context. Finally, there is skepticism around whether government regulators have the resources or political will to effectively monitor new digital media. As such, this paper considers not only the role of direct government regulation in monitoring and enforcing the regulation of DTCA, but also the role of third party oversight and industry self-regulation—both of which may play an important role in filling the gaps in the regulation of the Internet and social media.

  17. Alara applied to iter design and operation

    International Nuclear Information System (INIS)

    Uzan-Elbez, Joelle; Rodriguez-Rodrigo, Lina; Porfiri, Maria Teresa; Taylor, Neil; Gordon, Charles; Garin, Pascal; Girard, Jean-Philippe

    2005-01-01

    Based on the existing data on ITER and the safety options for licensing ITER in Cadarache, the present work assesses the application of the as-low-as-reasonably-achievable (ALARA) principle, as it has been implemented in the design of ITER and will be applied during ITER operation, as well as the compliance of the design with EUR/96-29 directive and regulation applicable in France. The preliminary occupational radiation exposure estimate gives a value of about 250 man mSv/a, which is half the annual target for ITER and comes essentially from maintenance activities. Some examples of the approach are presented

  18. International regulations on labour health and safety applied to fishing and maritime transport sectors. Are maritime workers under-protected.

    Science.gov (United States)

    Rodríguez, Julio Louro; Portela, Rosa Mary de la Campa; Pardo, Guadalupe Martín

    2012-01-01

    The work activity developed on board is of great importance in our nearby environment, and it has a series of peculiarities that determine the service rendering of sea workers. On the other hand, work at sea is developed on an international basis. Nowadays such work becomes a completely globalised industrial sector in relation to the elements that make up the ship's operation, including manpower. For that reason several relevant international organisations have paid attention to this industrial sector and have adopted a broad regulation on this matter. In the case of the European Union, the Community procedure emphasises enormous interest in providing specific and comprehensive training to seafarers, as well as in regulating working time on board with the aim of minimising the safety problems caused by fatigue. In the present article a schematic presentation of regulations on workers' health and occupational safety protection derived from the European Union, the International Maritime Organisation, and the International Labour Organisation has been done. Also it shows what parts of these regulations are not applicable to the work on board, and it reveals how the workers of fishing and maritime transport sectors are under-protected with regard to the guarantee of their health and occupational safety compared to workers in other sectors.

  19. ASPECTS CONCERNING INTERIM FINANCIAL REPORTING IN ROMANIA: STANDARDS AND REGULATIONS

    Directory of Open Access Journals (Sweden)

    Aristita Rotila

    2014-12-01

    Full Text Available The mechanisms employed for the communication of accounting information that is necessary for users in their economic decision-making process consist of the financial statements of an entity. All legal entities, no matter the domain of their activity, have the obligation to draw up annual financial statements for every completed financial year. For certain categories of entities, reporting obligations are also required for periods other than the annual reporting, throughout the financial year. It is the case of interim financial reporting. At the level of the international accounting framework, the aspects related to interim financial reporting are the subject of a separate standard, namely, IAS 34 Interim Financial Reporting. In Romania, the current system of accounting regulations concerning the annual financial statements comprises accounting regulations that comply with the European directives and which apply to the various categories of entities, on the one hand and, on the other, accounting regulations in line with the IFRS, which are applicable to other classes of entities from certain activity sectors. The accounting regulations that apply to each category refer to, among other things, the contents and the format of financial statements that have to be presented. Analysing the system of norms and regulations, this article identifies the requirements concerning interim financial reporting in Romania, with reference to the different types of entities.

  20. Metagenomic screening for aromatic compound-responsive transcriptional regulators.

    Directory of Open Access Journals (Sweden)

    Taku Uchiyama

    Full Text Available We applied a metagenomics approach to screen for transcriptional regulators that sense aromatic compounds. The library was constructed by cloning environmental DNA fragments into a promoter-less vector containing green fluorescence protein. Fluorescence-based screening was then performed in the presence of various aromatic compounds. A total of 12 clones were isolated that fluoresced in response to salicylate, 3-methyl catechol, 4-chlorocatechol and chlorohydroquinone. Sequence analysis revealed at least 1 putative transcriptional regulator, excluding 1 clone (CHLO8F. Deletion analysis identified compound-specific transcriptional regulators; namely, 8 LysR-types, 2 two-component-types and 1 AraC-type. Of these, 9 representative clones were selected and their reaction specificities to 18 aromatic compounds were investigated. Overall, our transcriptional regulators were functionally diverse in terms of both specificity and induction rates. LysR- and AraC- type regulators had relatively narrow specificities with high induction rates (5-50 fold, whereas two-component-types had wide specificities with low induction rates (3 fold. Numerous transcriptional regulators have been deposited in sequence databases, but their functions remain largely unknown. Thus, our results add valuable information regarding the sequence-function relationship of transcriptional regulators.

  1. A contact-force regulated photoplethysmography (PPG) platform

    Science.gov (United States)

    Sim, Jai Kyoung; Ahn, Bongyoung; Doh, Il

    2018-04-01

    A photoplethysmography (PPG) platform integrated with a miniaturized force-regulator is proposed in this study. Because a thermo-pneumatic type regulator maintains a consistent contact-force between the PPG probe and the measuring site, a consistent and stable PPG signal can be obtained. We designed and fabricated a watch-type PPG platform with an overall size of 35 mm × 19 mm. In the PPG measurement on the radial artery wrist while posture of the wrist is changed to extension, neutral, or flexion, regulation of the contact-force provides consistent PPG measurements for which the variations in the PPG amplitude (PPGA) was 7.2 %. The proposed PPG platform can be applied to biosignal measurements in various fields such as PPG-based ANS monitoring to estimate nociception, sleep apnea syndrome, and psychological stress.

  2. A contact-force regulated photoplethysmography (PPG platform

    Directory of Open Access Journals (Sweden)

    Jai Kyoung Sim

    2018-04-01

    Full Text Available A photoplethysmography (PPG platform integrated with a miniaturized force-regulator is proposed in this study. Because a thermo-pneumatic type regulator maintains a consistent contact-force between the PPG probe and the measuring site, a consistent and stable PPG signal can be obtained. We designed and fabricated a watch-type PPG platform with an overall size of 35 mm × 19 mm. In the PPG measurement on the radial artery wrist while posture of the wrist is changed to extension, neutral, or flexion, regulation of the contact-force provides consistent PPG measurements for which the variations in the PPG amplitude (PPGA was 7.2 %. The proposed PPG platform can be applied to biosignal measurements in various fields such as PPG-based ANS monitoring to estimate nociception, sleep apnea syndrome, and psychological stress.

  3. 24 CFR 943.151 - What procurement standards apply to a joint venture itself?

    Science.gov (United States)

    2010-04-01

    ... a joint venture itself? 943.151 Section 943.151 Housing and Urban Development Regulations Relating... HOUSING, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT PUBLIC HOUSING AGENCY CONSORTIA AND JOINT VENTURES Subsidiaries, Affiliates, Joint Ventures in Public Housing § 943.151 What procurement standards apply to a...

  4. Applied photovoltaics as a practical education in renewable energy technologies

    International Nuclear Information System (INIS)

    Stoev, Mitko

    2009-01-01

    The optional course „Applied Photovoltaic” for MEng students specializing in Electronics at the Faculty of Electronics and Automation, TU-Plovdiv is presented. The main topics of the advanced PV course as a modern sustainable energetic based on the photovoltaic effect and energy from Sun as a renewable energy source; materials and technologies in photovoltaic; design of solar cells and PV modules and PV generators up to 100 kWp; BIPV and CIPV systems; hybrid PV systems; PV mounting; monitoring of PV systems and EC regulations for PV systems connected to the utility grid are discussed. The advanced teaching method by online e-platform with virtual resources is presented. Key words: PV education, PV technologies, applied photovoltaic, e-platform

  5. [International trends of applied ecology and its future development in China].

    Science.gov (United States)

    Zhou, Qixing; Sun, Shunjiang

    2002-07-01

    Internationally applied ecology was born around 25-40 years ago in order to adapt and serve the needs of mitigating increasingly environmental pollution and ecological destroy in developed western countries at that time. All the times applied ecological principles thus underpin most efforts at solving increasingly deterioration of natural resources and serious eco-environmental problems as its keystone and researching kernel with the development of the subject. At the advent of the 21st century, human beings enter into the age of applied ecology. There are five international features of applied ecology, including more attention to many-sided applications, special emphasis on the intersection with engineering, strongly keeping on mutual links with basic ecology, omnidirectional adoption of new methods and new technology, and side-by-side trends of microcosmic mechanisms and macroscopical regulation. Although we must connect with international applied ecology and absorb distillates from the subject in developed western countries, development of applied ecology in China in the future, in particular, at the beginnings of the 21st century should not deviate from aiming at the solution of increasingly environmental pollution and ecological destroy that is one of the most important basic situations of the country.

  6. Next-Generation Entrepreneurs Ready to Advance Breast Cancer Research Innovations | Poster

    Science.gov (United States)

    By Michele Newton and Thomas Stackhouse, Contributing Writers, and Rosemarie Truman, Guest Writer Editor’s note: In May 2014, the Breast Cancer Start-Up Challenge was named one of six finalists in the HHS Innovates Award Competition. This award celebrates innovations developed by employees of the U.S. Department of Health and Human Services (HHS) to support the mission of HHS.

  7. Is anyone regulating naturally occurring radioactive material? A state survey

    International Nuclear Information System (INIS)

    Gross, E.M.; Barisas, S.G.

    1993-08-01

    As far as we know, naturally occurring radioactive material (NORM) has surrounded humankind since the beginning of time. However, recent data demonstrating that certain activities concentrate NORM have increased concern regarding its proper handling and disposal and precipitated the development of new NORM-related regulations. The regulation of NORM affects the management of government facilities as well as a broad range of industrial processes. Recognizing that NORM regulation at the federal level is extremely limited, Argonne National Laboratory (ANL) conducted a 50-state survey to determine the extent to which states have assumed the responsibility for regulating NORM as well as the NORM standards that are currently being applied at the state level. Though the survey indicates that NORM regulation comprises a broad spectrum of controls from full licensing requirements to virtually no regulation at afl, a trend is emerging toward recognition of the need for increased regulation of potential NORM hazards, particularly in the absence of federal standards

  8. 75 FR 18041 - Defense Federal Acquisition Regulation Supplement; Minimizing Use of Hexavalent Chromium (DFARS...

    Science.gov (United States)

    2010-04-08

    ...-AG35 Defense Federal Acquisition Regulation Supplement; Minimizing Use of Hexavalent Chromium (DFARS... Regulation Supplement (DFARS) to address requirements for minimizing the use of hexavalent chromium in... of items containing hexavalent chromium under DoD contracts unless an exception applies. DATES...

  9. Effect of gibberellin, auxin and kinetin treatments combined with foliar applied NPK on the yield of Capsicum annuum L. fruits and their capsaicin content

    Directory of Open Access Journals (Sweden)

    Tomasz J. Nowak

    2013-12-01

    Full Text Available The Wrocław version of hydroponic culture was applied. Under optimal conditions of root fertilization the plants were sprayed with growth regulators sueh as gibberellins, auxins and kinetins, and .their mixtures. Each growth regulator treatment was applied with or without NPK added. The influence of these treatments on the fresh and dry weight of the fruit, percentage of ripe fruits and content and yield of capsaicin was studied. The highest yield of fruits and capsaicin. was obtained from plants sprayed with gibberellic acid and kinetin (in concentrations of 10 and 5 mg/l, respectively together with NPK foliar application. No influence of ,growth regulators and foliar-applied NPK was noted on capsaicin content and dry weight of fruits.

  10. European Communities (Drinking water) Regulations, 2000

    International Nuclear Information System (INIS)

    2000-12-01

    These Regulations were adopted as Statutory Instrument No. 439 of 2000 on 18 December 2000 and come in to operation on 1 January 2004. The regulations give effect to provisions of EU Council Directive 98/83/EC on the quality of water intended for human consumption.. They prescribe quality standards to be applied in relation to certain supplies of drinking water. S.I. 439 of 2000 stipulates that the radiation dose arising from one year's consumption of drinking water should not exceed 0.1 mSv. It further stipulates that the dose calculation should include contributions from all natural and artificial radionuclides with the exception of tritium, potassium-40, radon and radon decay products

  11. Management information system applied to radiation protection services

    International Nuclear Information System (INIS)

    Grossi, Pablo Andrade; Souza, Leonardo Soares de; Figueiredo, Geraldo Magela; Figueiredo, Arthur

    2013-01-01

    An effective management information system based on technology, information and people is necessary to improve the safety on all processes and operations subjected to radiation risks. The complex and multisource information flux from all radiation protection activities on nuclear organizations requires a robust tool/system to highlight the strengths and weaknesses and identify behaviors and trends on the activities requiring radiation protection programs. Those organized and processed data are useful to reach a successful management and to support the human decision-making on nuclear organization. This paper presents recent improvements on a management information system based on the radiation protection directives and regulations from Brazilian regulatory body. This radiation protection control system is applied to any radiation protection services and research institutes subjected to Brazilian nuclear regulation and is a powerful tool for continuous management, not only indicating how the health and safety activities are going, but why they are not going as well as planned showing up the critical points. (author)

  12. Management information system applied to radiation protection services

    Energy Technology Data Exchange (ETDEWEB)

    Grossi, Pablo Andrade; Souza, Leonardo Soares de; Figueiredo, Geraldo Magela; Figueiredo, Arthur, E-mail: pabloag@cdtn.br, E-mail: lss@cdtn.br, E-mail: gmf@cdtn.br, E-mail: arthurqof@gmail.com [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil)

    2013-07-01

    An effective management information system based on technology, information and people is necessary to improve the safety on all processes and operations subjected to radiation risks. The complex and multisource information flux from all radiation protection activities on nuclear organizations requires a robust tool/system to highlight the strengths and weaknesses and identify behaviors and trends on the activities requiring radiation protection programs. Those organized and processed data are useful to reach a successful management and to support the human decision-making on nuclear organization. This paper presents recent improvements on a management information system based on the radiation protection directives and regulations from Brazilian regulatory body. This radiation protection control system is applied to any radiation protection services and research institutes subjected to Brazilian nuclear regulation and is a powerful tool for continuous management, not only indicating how the health and safety activities are going, but why they are not going as well as planned showing up the critical points. (author)

  13. Translation, cross-cultural adaptation, and validation of the Turkish version of the Harris Hip Score.

    Science.gov (United States)

    Çelik, Derya; Can, Canan; Aslan, Yasemin; Ceylan, Hasan Huseyin; Bilsel, Kerem; Ozdincler, Arzu Razak

    2014-01-01

    The Harris Hip Score (HHS) developed to assess function and pain from the perspective of patients hip pathologies. The purpose of this study was to translate and culturally adapt the HHS into Turkish, and thereby determine the reliability and validity of the translated version. The HHS was translated into Turkish in accordance with the stages recommended by Beaton. The measurement properties of the HHS were tested in 80 patients; 52 males, mean age 51 years (range 21-75 years) suffering from different hip pathologies. The test-retest reliability was tested in 58 patients; 28 males mean age, 52 years (range 30-73 years) after an interval of seven days. The Cronbach's Alpha was used to assess internal consistency and the intra-class correlation coefficient (ICC) was used to estimate the test-retest reliability. Patients were asked to answer the Oxford Hip Score (OHS), the Western Ontario and McMaster Universities Arthritis Index (WOMAC), the VAS and the Short Form-36 (SF-36) for the validity of the estimation. The Turkish version of the HHS showed sufficient internal consistency (Cronbach's alpha,0.70) and test-retest reliability (ICC = 0.91). The correlation coefficients between the HHS, the WOMAC and the OHS were 0.64 and 0.89 respectively. The highest correlations between the HHS and SF-36 were with the physical function scale (r = 0.72), and the lowest correlations were with the mental function scale (r = 0.10). We observed no floor or ceiling effects. The Turkish version of the HHS has sufficient reliability and validity to measure patient-reported outcome for Turkish-speaking individuals with a variety of hip disorders.

  14. Public regulation of nuclear plants

    International Nuclear Information System (INIS)

    Burtheret, M.; Cormis, de

    1980-01-01

    The construction and operation of nuclear plants are subject to a complex system of governmental administration. The authors list the various governmental authorisations and rules applicable to these plants. In the first part, they describe the national regulations which relate specifically to nuclear plants, and emphasize the provisions which are intended to ensure the safety of the installations and the protection of the public against ionizing radiation. However, while the safety of nuclear plants is a major concern of the authorities, other interests are also protected. This is accomplished by various laws or regulations which apply to nuclear plants as well as other industrial installations. The duties which these texts, and the administrative practice based thereon, impose on Electricite de France are covered in the second part [fr

  15. Essential health benefits and the Affordable Care Act: law and process.

    Science.gov (United States)

    Bagley, Nicholas; Levy, Helen

    2014-04-01

    Starting in 2014, the Affordable Care Act (ACA) will require private insurance plans sold in the individual and small-group markets to cover a roster of "essential health benefits." Precisely which benefits should count as essential, however, was left to the discretion of the Department of Health and Human Services (HHS). The matter was both important and controversial. Nonetheless, HHS announced its policy by posting on the Internet a thirteen-page bulletin stating that it would allow each state to define essential benefits for itself. On both substance and procedure, the move was surprising. The state-by-state approach departed from the uniform, federal standard that the ACA appears to anticipate and that informed observers expected HHS to adopt. And announcing the policy through an Internet bulletin appeared to allow HHS to sidestep traditional administrative procedures, including notice and comment, immediate review in the courts, and White House oversight. This article explores two questions. First, is the state-by-state approach a lawful exercise of HHS's authority? Second, did HHS in fact evade the procedural obligations that are meant to shape the exercise of its discretion?

  16. 40 CFR 80.382 - What requirements apply to gasoline for use in American Samoa, Guam and the Commonwealth of the...

    Science.gov (United States)

    2010-07-01

    ... sulfur standards of §§ 80.195 and 80.240(a) do not apply to gasoline that is produced, imported, sold... 40 Protection of Environment 16 2010-07-01 2010-07-01 false What requirements apply to gasoline...) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Sulfur Exemptions § 80.382 What requirements apply to...

  17. The redefinition of the american and british gas industries: the regulation of the access load to the gas pipelines networks

    International Nuclear Information System (INIS)

    David, L.

    2000-10-01

    The transport and distribution networks regulation is the main stakes of the regulation reform of the gas industries. This thesis analyzes the models applied in The Usa and in the United Kingdom. The first part deals with the gas industries deregulation in these two countries, the impacts on the economy and the organization of the gas industries. The second part presents a theoretical approach of the regulation applied to the prices of the natural ags transport by gas pipelines. Regulation by the service cost price and by price cap are compared. (A.L.B.)

  18. APPLICABILITY OF CONSOLIDATED TECHNIQUES IN THE VIEW OF ROMANIAN ACCOUNTING REGULATIONS

    Directory of Open Access Journals (Sweden)

    Cristina Rosu

    2016-06-01

    Full Text Available The accounting regulations are more and more interested in groups of companies. In some cases, these regulations require for preparing the consolidated financial statements. This is the task of the parent company who keeps the consolidated accounts. To accomplish its goals, the consolidated accounting uses a couple of, so-called, consolidation techniques. These are applied in the case of groups of companies with a complex structure. Their goal is to elaborate the consolidated financial statements using a set of methods and empirical skills. In this article we synthetize and apply the consolidation techniques in the view of Romanian accounting regulations. The Romanian practice has revealed, especially, two techniques: one based on direct consolidation and another one based on multiple levels (phased consolidation. Therefore, this work regards only the technical side of consolidated accounting, accounting records being evaded. Furthermore, we focus only on the preparation of the consolidated balance sheet in the case of some hypothetical groups of companies.

  19. Regulating interface science healthcare products: myths and uncertainties.

    Science.gov (United States)

    Bravery, Christopher A

    2010-12-06

    Whenever new technology emerges it brings with it concerns and uncertainties about whether or how it will need to be regulated, particularly when it is applied to human healthcare. Drawing on the recent history in the European Union (EU) of the regulation of cell-based medicinal products, and in particular tissue-engineered products, this paper explores the myths that persist around their regulation and speculates on whether the existing regulatory landscape in the EU is flexible enough to incorporate nanotechnology and other new technologies into healthcare products. By untangling these myths a number of clear conclusions are revealed that, when considered in the context of risk-benefit, make it clear that what hinders the uptake of new technology is not regulatory process but basic science.

  20. Exploring car manufacturers' responses to technology-forcing regulation : The case of California's ZEV mandate

    NARCIS (Netherlands)

    Wesseling, Joeri; Farla, J. C M; Hekkert, M. P.

    2015-01-01

    The ability of firms to influence environmental regulation has largely been overlooked in transition studies. We study how car manufacturers combine and change their innovation and political influence strategies in response to a technology-forcing regulation. We apply a conceptual framework on

  1. Taxation and regulation of petroleum companies under asymmetric information; a monograph

    Energy Technology Data Exchange (ETDEWEB)

    Osmundsen, P

    1994-12-01

    The report relates to the taxation and regulation of petroleum companies. The main topics of this report are as follow: Taxation and regulation of petroleum companies under asymmetric information. A discussion of incentive problems and the principles for applying principal-agent analysis; taxation and regulation of petroleum companies under asymmetric information. A static adverse selection model; Petroleum Taxation with adverse selection. Interactions of dynamics in costs and information; Adverse selection and moral hazard in the petroleum industry, repeated auctions of incentive contracts; Petroleum taxation and regulation. Policy implications from principal-agent theory, and a comparison with the current Norwegian system. 54 refs., 7 figs.

  2. Taxation and regulation of petroleum companies under asymmetric information; a monograph

    International Nuclear Information System (INIS)

    Osmundsen, P.

    1994-12-01

    The report relates to the taxation and regulation of petroleum companies. The main topics of this report are as follow: Taxation and regulation of petroleum companies under asymmetric information. A discussion of incentive problems and the principles for applying principal-agent analysis; taxation and regulation of petroleum companies under asymmetric information. A static adverse selection model; Petroleum Taxation with adverse selection. Interactions of dynamics in costs and information; Adverse selection and moral hazard in the petroleum industry, repeated auctions of incentive contracts; Petroleum taxation and regulation. Policy implications from principal-agent theory, and a comparison with the current Norwegian system. 54 refs., 7 figs

  3. Legal issues in amending nuclear rules and regulations

    International Nuclear Information System (INIS)

    Ossenbuehl, F.

    2006-01-01

    Nuclear rules and regulations are composed of a multitude of provisions, benchmarks, etc. of different origins and different levels of legal quality. The Safety Criteria and Guidelines for Nuclear Power Plants published in the 'Bundesanzeiger' (Federal Gazette) by the competent federal ministry after consultation of the competent highest state authorities are of particular importance. The Safety Criteria were adopted by the States Committee for Atomic Energy on October 12, 1977 and published in the 'Bundesanzeiger'. The Federal Ministry for the Environment, Nature Conservation, and Nuclear Safety (BMU) intends to revise and amend the contents of the safety criteria and guidelines applying to nuclear power plants. The question underlying this article is this: In what legal way can such an 'amendment' be achieved in a permissible fashion? This leaves out of consideration the question of the contents and applicability of amended provisions, such as the question to what extent amended regulations can also be applied to the nuclear power plants already licensed and in operation, or whether the concept of finality and the constitutional ban on retroactive effect or other constitutional or paramount rules contain restrictions on the contents of such regulations. Solely the question of a permissible amending procedure is under study. (orig.)

  4. [Regulation of sporulation by two-component system YvcPQ in Bacillus thuringiensis].

    Science.gov (United States)

    Fan, Qingyun; Zhang, Shumeng; Gong, Yujing; He, Jin

    2017-01-04

    To study the regulation of sporulation controlled by two-component system (TCS) YvcPQ. β-galactosidase experiment was used to verify the regulation of YvcP on kapD expression; bacterial one-hybrid assay, EMSA and RT-qPCR were applied to study the regulation of AbrB on yvcPQ expression; markerless gene deletion coupled with spore count was used to reveal the influence of yvcPQ and kapD expressions on sporulation. transcriptional regulator AbrB up-regulated the expression of yvcPQ; YvcP promoted the expression of kapD to inhibit sporulation. AbrB up-regulated the transcription of yvcPQ operon, then the increased YvcP strengthened the transcriptional acitivation of sporulation inhibitor gene kapD, and subsequently inhibited sporulation.

  5. Alternative development and action plan for the atomic safety regulation instruments

    International Nuclear Information System (INIS)

    Kim, J. Y.; Ahn, S. K.; Ham, Y. S.

    2004-01-01

    The goal of this study to provide highly practical model to regulation agency. Since nuclear power safety regulation has different characteristics, compared to general regulation, it is important to have new point of view and approach. But application possibility for regulation that guarantees the 'perfect safety' is very low. Therefore, it is important establish nuclear power safety regulation that is realistic as well as safety securing. In order to establish high quality regulation, evaluation of existing regulation must be done first. Thus in this study, 6 standards to evaluate existing regulation are suggested. They are clearness, efficiency, flexibility, reliability, responsibility and political consideration. Also, strategies to complement the weak points of regulatory governance, regulatory sunset, regulatory map, regulatory negotiation, regulatory benefit cost analysis, etc. These strategies can be applied all in one regulation, and can strategically be selected for application. After analyzing the result if case analysis on nuclear furnace regulation for research study, agreement was made that it is most efficient to consider in the order if clearness reliability, flexibility, confidence, political consideration, administrative efficiency and economic efficiency

  6. Government regulation as an impetus for innovation: Evidence from energy performance regulation in the Dutch residential building sector

    International Nuclear Information System (INIS)

    Beerepoot, Milou; Beerepoot, Niels

    2007-01-01

    The recent implementation of energy performance policy as a way to tackle energy consumption in the building sector in Europe draws attention to the effect it has on the development and diffusion of energy-saving innovations. According to innovation system literature, government regulation through norms and standards is one of the factors stimulating innovation. This paper concentrates on the role of stricter government regulation as an incentive to innovation in the Dutch residential building sector. Innovation in this sector is predominantly a process of applying incremental modifications to comply with new and stricter government regulations and standards. Energy performance policy in its current shape will therefore not contribute to the diffusion of really new innovation in energy techniques for residential buildings in the Netherlands. If diffusion of really new innovation is an explicit aim of energy performance policy then the European wide introduction of this scheme needs reconsideration

  7. Nonlinear Model-Based Predictive Control applied to Large Scale Cryogenic Facilities

    CERN Document Server

    Blanco Vinuela, Enrique; de Prada Moraga, Cesar

    2001-01-01

    The thesis addresses the study, analysis, development, and finally the real implementation of an advanced control system for the 1.8 K Cooling Loop of the LHC (Large Hadron Collider) accelerator. The LHC is the next accelerator being built at CERN (European Center for Nuclear Research), it will use superconducting magnets operating below a temperature of 1.9 K along a circumference of 27 kilometers. The temperature of these magnets is a control parameter with strict operating constraints. The first control implementations applied a procedure that included linear identification, modelling and regulation using a linear predictive controller. It did improve largely the overall performance of the plant with respect to a classical PID regulator, but the nature of the cryogenic processes pointed out the need of a more adequate technique, such as a nonlinear methodology. This thesis is a first step to develop a global regulation strategy for the overall control of the LHC cells when they will operate simultaneously....

  8. Regulation of water, salinity, and cold stress responses by salicylic acid

    Directory of Open Access Journals (Sweden)

    Kenji eMiura

    2014-01-01

    Full Text Available Salicylic acid (SA is a naturally occurring phenolic compound. SA plays an important role in the regulation of plant growth, development, ripening, and defense responses. The role of SA in the plant-pathogen relationship has been extensively investigated. In addition to defense responses, SA plays an important role in the response to abiotic stresses, including drought, low temperature, and salinity stresses. It has been suggested that SA has great agronomic potential to improve the stress tolerance of agriculturally important crops. However, the utility of SA is dependent on the concentration of the applied SA, the mode of application, and the state of the plants (e.g., developmental stage and acclimation. Generally, low concentrations of applied SA alleviate the sensitivity to abiotic stresses, and high concentrations of applied induce high levels of oxidative stress, leading to a decreased tolerance to abiotic stresses. In this chapter, the effects of SA on the water stress responses and regulation of stomatal closure are reviewed.

  9. A responsible agenda for applied linguistics: Confessions of a philosopher

    Directory of Open Access Journals (Sweden)

    Albert Weideman

    2011-08-01

    Full Text Available When we undertake academic, disciplinary work, we rely on philosophical starting points. Several straightforward illustrations of this can be found in the history of applied linguistics. It is evident from the history of our field that various historically influential approaches to our discipline base themselves upon different academic confessions. This paper examines the effects of basing our applied linguistic work on the idea that applied linguistics is a discipline concerned with design. Such a characterisation does justice to both modernist and postmodernist emphases in applied linguistics. Conceptualisations of applied linguistics that came with the proposals for communicative language teaching (CLT some thirty to forty years ago propelled the discipline squarely into postmodern times. To account for this, we need to develop a theory of applied linguistics which shows what constitutive and regulative conditions exist for doing applied linguistic designs. A responsible agenda for applied linguistics today has as its first responsibility to free the users of its designs from toil and drudgery, as well as from becoming victims of fashion, ideology or theory. Secondly, it should design solutions to language problems in such a way that the technical imagination of the designer is not restricted but supported by theory and empirical investigation, and that the productive pedagogical fantasy of the implementers of such plans is set free. Thirdly, it must seek to become accountable by designing theoretically and socially defensible solutions to language problems, solutions that relieve some of the suffering, pain, poverty and injustice in our world.

  10. X - FACTOR EVALUATION UNDER RPI-X REGULATION FOR INDIAN ELECTRICITY DISTRIBUTION UTILITIES

    Directory of Open Access Journals (Sweden)

    PAVAN KHETRAPAL

    2017-07-01

    Full Text Available With regulators’ growing interest in improving operational efficiency and quality supply, the time is nearing when performance based regulation will become norm for regulating the distribution tariff in Indian electricity distribution sector. In this context, the State Electricity Regulatory Commissions proposed replacing rate-of-return regulation with most commonly used performance based regulatory regime, i.e., Price Cap regulation also known as RPI-X (Retail Price Index - Productivity Offset regulatory framework. However, the potential problem associated with applying price cap regulation scheme in practice is the determination of productivity offset or X factor used in price caps setting. This paper proposed an approach to calculate the X-factor for 58 government-owned and privately-owned electricity distribution utilities in India during a five year period from 2007/08 to 2011/12. A Stochastic Frontier model through an input distance function is first applied to compute the Malmquist Total Factor Productivity (TFP and the estimated TFP is then used to calculate the utility-specific X-factor. With rely on calculated X-factor, the distribution utilities would be able to cap either on prices or revenues thus accounting the inflation in the tariff determination. This will be more realistic approach as compared to cost plus approach.

  11. Investment and revenue cap under incentive regulation: The case study of the Norwegian electricity distributors

    OpenAIRE

    Zhang, Dengjun; Xie, Jinghua

    2017-01-01

    Source at https://doi.org/10.1080/23322039.2017.1400900 Electricity distribution operators are regulated as monopolies around the world. Incentive regulation is further applied to relate their allowed revenues (revenue cap) to cost efficiency and investment. Incentive regulation varies cross countries and has evolved over time for individual countries. Norway is one of the first countries reforming the network distributors by incentive regulation. Using the long time series data, we eval...

  12. 10 CFR 603.125 - Applicability of other parts of the DOE Assistance Regulations.

    Science.gov (United States)

    2010-01-01

    ... Regulations. 603.125 Section 603.125 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS TECHNOLOGY...: (1) 10 CFR part 601—lobbying restrictions apply by law (31 U.S.C. 1352) to a TIA that is a... nonprocurement instruments in general; and (3) 10 CFR part 607—drug-free work-place (financial assistance...

  13. ‘Standard’ incentive regulation hinders the integration of renewable energy generation

    International Nuclear Information System (INIS)

    Nykamp, Stefan; Andor, Mark; Hurink, Johann L.

    2012-01-01

    The connection and distribution of growing, decentralized electricity generation from renewable energy sources (RES-E) is leading to massive investment needs. Besides investing in additional ‘conventional’ assets (e.g. cables), grid operators can also invest in innovative ‘smart solutions’ like local storage capacities or voltage regulation appliances, which may be a more suitable way of integrating RES-E. This paper investigates the influence of incentive regulation on the investment decision of grid operators to integrate RES-E. We describe the technical and regulatory background, explain the advantages of ‘smart solutions’ and present an approach for comparing investment scenarios. As an example, we calculate the profitability of investments in a case study of the German electricity market. We apply Data Envelopment Analysis (DEA) and Stochastic Frontier Analysis (SFA) to show the influence of the investment alternatives on grid operator efficiency objectives. We demonstrate that under current ‘standard’ incentive regulation, the grid operators gain profitability by avoiding investments and – if they are forced to invest – by not implementing ‘smart solutions’. The results highlight the need to consider innovation in the regulation design. Further research should investigate specific instruments that can be used to account for innovation. Our brief discussion of such instruments provides a starting point. - Highlights: ► We measure the influence of investments on efficiency by applying DEA and SFA. ► We compare the profitability of alternative investments under incentive regulation. ► Incentive regulation gives incentives to refuse investment at all. ► If DSOs are forced to invest, reinforcement is preferable to smart solutions. ► Ways to consider innovation in incentive regulations are required and discussed.

  14. Proposal of requirements for performance in Brazil for systems of external individual monitoring for neutrons applying the TLD-albedo technique

    International Nuclear Information System (INIS)

    Martins, Marcelo M.; Mauricio, Claudia L.P.; Pereira, Walsan W.; Fonseca, Evaldo S. da; Silva, Ademir X.

    2009-01-01

    This work presents a criteria and conditions proposal for the regulations in Brazil of individual monitoring systems for neutrons applying the albedo technique with thermoluminescent detectors. Tests are proposed for the characterization performance of the system based on the Regulation ISO 21909 and on the experience of the authors

  15. Cost of Capital in Price-regulated Companies: the Case of Estonia

    Directory of Open Access Journals (Sweden)

    Priit Sander

    2013-01-01

    Full Text Available In case of price-regulated companies it is the role of appropriate government agencies to introduce clear, internally consistent, theoretically sound, and unambiguous methodology for finding the regulative cost of capital. The aim of the paper is to describe and analyze the cost of capital estimation methodology for regulated companies in Estonia and discuss some issues arising in applying this methodology. The current paper focuses on two topical issues associated with the estimation of regulative cost of capital in Estonia: estimation of market risk premium and inclusion of currency risk premium into the cost of capital. Current turmoil in financial markets has increased investors’ risk aversion as well as level of risks.

  16. Self-regulation theory: applications to medical education: AMEE Guide No. 58.

    Science.gov (United States)

    Sandars, John; Cleary, Timothy J

    2011-01-01

    Self-regulation theory, as applied to medical education, describes the cyclical control of academic and clinical performance through several key processes that include goal-directed behaviour, use of specific strategies to attain goals, and the adaptation and modification to behaviours or strategies to optimise learning and performance. Extensive research across a variety of non-medical disciplines has highlighted differences in key self-regulation processes between high- and low-achieving learners and performers. Structured identification of key self-regulation processes can be used to develop specific remediation approaches that can improve performance in academic and complex psycho-motor skills. General teaching approaches that are guided by a self-regulation perspective can also enhance academic performance. Self-regulation theory offers an exciting potential for improving academic and clinical performance in medical education.

  17. Developments in the regulation of research reactors

    International Nuclear Information System (INIS)

    Loy, J.

    2003-01-01

    The International Atomic Energy Agency (IAEA) has data on over 670 research reactors in the world. Fewer than half of them are operational and a significant number are in a shutdown but not decommissioned state. The International Nuclear Safety Advisory Group (INSAG) has expressed concerns about the safety of many research reactors and this has resulted in a process to draw up an international Code of Conduct on the Safety of Research Reactors. The IAEA is also reviewing its safety standards applying to research reactors. On the home front, regulation of the construction of the Replacement Research Reactor continues. During the construction phase, regulation has centred around the consideration of Requests for Approval (RFA) for the manufacture and installation of systems, structures and components important for safety. Quality control of construction of systems, structures and components is the central issue. The process for regulation of commissioning is under consideration

  18. Power Quality Regulation from an Economical and a Technical Point of View

    International Nuclear Information System (INIS)

    Partanen, Jarmo; Viljainen, Satu; Lassila, Jukka; Honkapuro, Samuli; Tahvanainen, Kaisa; Jaerventausta, Pertti; Maekinen, Antti; Kivikko, Kimmo

    2005-06-01

    An essential guideline for the implementation of power quality regulation - or any regulation for that matter - is that it needs to find the right balance between the interests of the different stakeholders. This is particularly important when assessing the inconvenience caused to customers by the failures in the electricity supply. Customers' experiences should obviously not be underestimated but it is equally important that excessive requirements concerning the power quality developments are not laid on the distribution companies, either - especially if they are not provided with adequate means to carry out the necessary developments. After all, regulation should encourage innovations, both organisational and technological, that benefit the industry in the long run - this applies to power quality developments as well as any other developments within the industry. Failing to do this, the investors will soon loose their interest in the electricity distribution business, and this will be extremely harmful for the capital-intensive industry. Regulators are currently developing versatile power quality regulation schemes in different countries. At this point it might be worth considering what benefits could be achieved if the framework for the power quality regulation schemes that are applied in different countries was the same - after all the goals are principally the same anyway. One of the obvious benefits would be that the regulators would have more comparable data on the observed power quality levels in different countries. In addition, those companies that operate in various markets could more easily transfer their best practices concerning the power quality developments from one market to another

  19. 45 CFR 286.140 - What special provisions apply to victims of domestic violence?

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false What special provisions apply to victims of domestic violence? 286.140 Section 286.140 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL TANF PROVISIONS...

  20. 34 CFR 660.4 - What definitions apply to the International Research and Studies Program?

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false What definitions apply to the International Research and Studies Program? 660.4 Section 660.4 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION THE INTERNATIONAL RESEARCH...

  1. 34 CFR 658.2 - Who is eligible to apply for assistance under this program?

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false Who is eligible to apply for assistance under this program? 658.2 Section 658.2 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION UNDERGRADUATE INTERNATIONAL STUDIES...

  2. 24 CFR 943.150 - What procurement standards apply to a PHA's joint venture partner?

    Science.gov (United States)

    2010-04-01

    ... a PHA's joint venture partner? 943.150 Section 943.150 Housing and Urban Development Regulations... HOUSING, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT PUBLIC HOUSING AGENCY CONSORTIA AND JOINT VENTURES Subsidiaries, Affiliates, Joint Ventures in Public Housing § 943.150 What procurement standards apply to a PHA...

  3. 76 FR 39242 - Federal Acquisition Regulation; TINA Interest Calculations

    Science.gov (United States)

    2011-07-05

    ... pricing data. This rule replaces the term ``simple interest'' as the requirement for calculating interest...-AL73 Federal Acquisition Regulation; TINA Interest Calculations AGENCIES: Department of Defense (DoD... interest calculations be applied to Government overpayments as a result of defective cost or pricing data...

  4. Regulations of 1 March 1983 relating to production, imports and sales of radioisotopes

    International Nuclear Information System (INIS)

    1983-01-01

    These regulations were issued by the Ministry of Health and Social Affairs, pursuant to the Act of 19th June 1938 on the use of radium and X-rays etc. The Regulations came into force on the date they were issued. They apply to radioisotopes used for industrial, commercial, agricultural, medical and scientific purposes. (NEA) [fr

  5. 78 FR 42951 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Public...

    Science.gov (United States)

    2013-07-18

    ... the document identifier HHS-OS-19133-30D for reference. Information Collection Request Title: MOVE... and Human Services (HHS) Coordinating Committee on Lesbian, Gay, Bi-sexual and Transgender (LGBT...

  6. The Concept of Human Functional State in Russian Applied Psychology

    Directory of Open Access Journals (Sweden)

    Anna B. Leonova

    2009-01-01

    Full Text Available The concept of human functional states (HFS is considered in the framework of activity regulation approach developed in Russian applied psychology. Aimed at the analysis of changes in regulatory mechanisms of on-going activity, structural methods for multilevel assessment of workers’ states are discussed. Three different strategies of data integration are proposed regarding the types of essential practical problems. Their usability is exemplified with the help of two empirical studies concerned with reliability of fire-fighters’ work in the Chernobyl Zone and effects of interruptions in computerized office environment. A general framework for applied HFS research is proposed in order to develop new ecologically valid psychodiagnostic procedures that can help to create efficient stress-management programs for enhancing human reliability and performance in complex job environment.

  7. Regulations on handling dangerous objects in Japan (with particular reference to sodium)

    International Nuclear Information System (INIS)

    Nagai, M.

    1971-01-01

    Sodium is designated as a kind of dangerous object, so that special care has to be taken in handling or storing large amounts of sodium. Formal regulations on sodium handling in Japan are prescribed in Fire Service Law, which is supplemented by Rules on Handling Dangerous Objects. Since these regulations are not intended to be applied to large sodium circuits, some defects and inappropriate expressions might be found in them. An attempt is made here to pick up these problems and important points from Japanese regulations on handling dangerous objects with particular reference to sodium

  8. Application of the regulations on pressurized components or light water reactor primary coolant circuits

    International Nuclear Information System (INIS)

    Barthelemy, F.; Menjon, G.

    1977-01-01

    This paper describes the philosophy and the provisions of the Order of 26 February 1974 concerning application of the regulations on pressurized components for light water reactor steam supply systems. The aim is to show how these regulations which differ from other regulations on pressurized components and is more detailed on many points, is applied in practice in France in the various stages of the design, construction and operation of PWRs. (NEA) [fr

  9. 34 CFR 660.2 - Who is eligible to apply for grants under this program?

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false Who is eligible to apply for grants under this program? 660.2 Section 660.2 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION THE INTERNATIONAL RESEARCH AND STUDIES PROGRAM...

  10. 45 CFR 2540.201 - What suitability criteria must I apply to a covered position?

    Science.gov (United States)

    2010-10-01

    ... covered position? 2540.201 Section 2540.201 Public Welfare Regulations Relating to Public Welfare... apply to a covered position? An individual is ineligible to serve in a covered position if the individual: (a) Is registered, or required to be registered, on a State sex offender registry or the National...

  11. 31 CFR 344.8 - What other provisions apply to subscriptions for Demand Deposit securities?

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false What other provisions apply to subscriptions for Demand Deposit securities? 344.8 Section 344.8 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY BUREAU OF THE PUBLIC...

  12. Signaling pathways in PACAP regulation of VIP gene expression in human neuroblastoma cells

    DEFF Research Database (Denmark)

    Falktoft, B.; Georg, B.; Fahrenkrug, J.

    2009-01-01

    Ganglia expressing the neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) innervate vasoactive intestinal peptide (VIP) containing neurons suggesting a role of PACAP in regulating VIP expression. Human NB-1 neuroblastoma cells were applied to study PACAP regulated VIP gene...... in PACAP regulation of the FOS and VIP gene expressions suggest for the first time a role of FOS in PACAP-induced VIP gene expression in human NB-1 neuroblastoma cells. (C) 2009 Elsevier Ltd. All rights reserved Udgivelsesdato: 2009/10...

  13. 78 FR 56897 - Agency Information Collection Activities; Proposed Collection; Public Comment Request

    Science.gov (United States)

    2013-09-16

    ... Health and Human Services (HHS), HHS collects some basic information about the company's product through... necessity and utility of the proposed information collection for the proper performance of the agency's...

  14. 77 FR 31856 - Meeting of the Chronic Fatigue Syndrome Advisory Committee

    Science.gov (United States)

    2012-05-30

    ... streamed at www.HHS.gov/Live and archived through the CFSAC Web site: www.hhs.gov/advocomcfs . Listening... not include sensitive personal information, such as social security number, birthdates, driver's...

  15. Applied Linguistics and the "Annual Review of Applied Linguistics."

    Science.gov (United States)

    Kaplan, Robert B.; Grabe, William

    2000-01-01

    Examines the complexities and differences involved in granting disciplinary status to the role of applied linguistics, discusses the role of the "Annual Review of Applied Linguistics" as a contributor to the development of applied linguistics, and highlights a set of publications for the future of applied linguistics. (Author/VWL)

  16. Regulations and classification advice: transport safety

    International Nuclear Information System (INIS)

    Davies, M.; Owen, K.

    1990-01-01

    The packaging of radioactive material for transport must conform with the regulations of the International Atomic Energy Agency (IAEA). These regulations are extensive and complex and require specialist interpretation. Packaging must be designed to contain the material, to limit radiation to safe levels, and to maintain the material in a safe state under both normal and accident conditions. British Nuclear Fuels Ltd. (BNFL) developed the TRANAID expert system to provide automated expert advice on the subject. It is used at BNFL and by other users internationally. The system was produced to meet an internal BNFL emphasis on accurate consistent and reliable interpretation of the complex IAEA regulations; and to provide a commercial product which would meet an external need. TRANAID provides reliable and consistent advice on safe transport procedures which reduce the workload on scarce skilled personnel, and allows them to concentrate on their primary task of packaging design. TRANAID also avoids overclassifying radioactive shipments, which would lead to the use of more expensive packaging than strictly is required. The IAEA regulations are applied internationally, and so there is a large potential worldwide market. The indications from the initial response are that future sales and use are expected to more than cover the investment. Other non-quantifiable benefits include the provision of consistent advice within a uniform approach, the safe-guarding of knowledge of the IAEA regulations, training and improvement in the expertise of users, improved management control, and enhancement of the professional image of BNFL. (author)

  17. Non-uniform regulations of underground storage tanks in the United States

    International Nuclear Information System (INIS)

    Nadim, F.; Hoag, G.E.; Liu, S.; Carley, R.J.; Zack, P.

    2000-01-01

    Leaking underground storage tanks (USTs) are one of the major sources of ground water contamination. United States federal regulations for USTs were established in September of 1988. Since that time little or no amendments have been made to these regulations. In order to protect sensitive areas such as aquifer recharge zones for public water supply wells and wetlands, different states have been obligated to apply more stringent standards than the federal UST regulations. This practice however, has led to a non-uniform application of regulations for USTs throughout the country. In this article, United States regulations for USTs are reviewed and its deficits are highlighted. Based on these regulations and the experience of northeastern states of United States, a sequence of leak and spill preventive measures for USTs is proposed. Application of the proposed measures could substantially reduce the possibility of UST failure and would be more protective of the subsurface environment. (author)

  18. Regulation and competition in United Kingdom electricity and gas industries

    International Nuclear Information System (INIS)

    McGowan, F.

    1992-01-01

    Focussing on the role of regulation in developing competition, this paper reviews the development of a regulation system to monitor and control prices, as well as, quality of service, in the UK's recently privatized electricity and gas industries. The review covers: the control mechanisms applied to the natural gas tariff and contract markets in the area of common carriage; performance monitoring and the concept of yardstick competition in the electric power industry; and the management and control, by OFFER (Office of Electricity Regulation), of the total 'pool' of generated electricity. It is noted that whereas Great Britain's particular energy supply situation permits this nation to attempt privatization/competition regulation, the energy balances of other European countries make similar attempts, for them, risky. The UK experience with privatization/competition regulation so far has shown that regulation is indispensable in guaranteeing competition, and that the incorporation of the controlling board within the framework of anti-trust legislation and the granting of full autonomy to this board has greatly favoured its effectiveness

  19. 77 FR 57089 - Meeting of the Chronic Fatigue Syndrome Advisory Committee

    Science.gov (United States)

    2012-09-17

    ... streamed at www.HHS.gov/Live and archived through the CFSAC Web site: www.hhs.gov/advocomcfs . Listening..., such as social security number, birthdates, driver's license number, state identification or foreign...

  20. Household Obesity Prevention: Take Action—a Group-Randomized Trial

    Science.gov (United States)

    French, Simone A.; Gerlach, Anne F.; Mitchell, Nathan R.; Hannan, Peter J.; Welsh, Ericka M.

    2018-01-01

    The purpose of the present study was to evaluate an intervention to prevent weight gain among households (HHs) in the community. Ninety HHs were randomized to intervention or control group for 1 year. Intervention consisted of six face-to-face group sessions, placement of a television (TV) locking device on all home TVs, and home-based intervention activities. Measures were collected in person at baseline and 1 year. Weight, height, eating behaviors, physical activity (PA), and TV viewing were measured among HH members ages ≥12 years. Follow-up rate at 1 year was 96%. No significant intervention effects were observed for change in HH BMI-z score. Intervention HHs significantly reduced TV viewing, snacks/sweets intake, and dollars per person spent eating out, and increased (adults only) PA and self-weighing frequency compared with control HHs. A 1 year obesity prevention intervention targeting entire HHs was effective in reducing TV viewing, snack/sweets intake and eating out purchases. Innovative methods are needed to strengthen the home food environment intervention component. Longer intervention durations also need to be evaluated. PMID:21212771

  1. The Control of Pollution (Radioactive Waste) Regulations 1976 of 10 June 1976

    International Nuclear Information System (INIS)

    1976-01-01

    The discharge into a public sewer of trade effluent is governed by the Control of Pollution Act 1974, under which water authorities in England and Wales have certain powers to regulate such discharges. These provisions have not however applied hitherto to radioactive waste, the disposal of which required mainly authorisation by the Minister of State for the Environment. Under the present Regulations, the 1974 Act will apply to radioactive waste so as to give water authorities control over liquid discharges into their sewers, notwithstanding that they contain radioactive waste while the powers of the Minister of State are maintained regarding control and disposal of the radioactive parts of such waste under the 1960 act on Radioactive substances. (N.E.A.) [fr

  2. Large-Scale Phosphoproteomics Reveals Shp-2 Phosphatase-Dependent Regulators of Pdgf Receptor Signaling

    DEFF Research Database (Denmark)

    Batth, Tanveer S; Papetti, Moreno; Pfeiffer, Anamarija

    2018-01-01

    Despite its low cellular abundance, phosphotyrosine (pTyr) regulates numerous cell signaling pathways in health and disease. We applied comprehensive phosphoproteomics to unravel differential regulators of receptor tyrosine kinase (RTK)-initiated signaling networks upon activation by Pdgf-ββ, Fgf-2...... of Pdgfr pTyr signaling. Application of a recently introduced allosteric Shp-2 inhibitor revealed global regulation of the Pdgf-dependent tyrosine phosphoproteome, which significantly impaired cell migration. In addition, we present a list of hundreds of Shp-2-dependent targets and putative substrates...

  3. 34 CFR 661.2 - Who is eligible to apply for a grant under the Business and International Education Program?

    Science.gov (United States)

    2010-07-01

    ... INTERNATIONAL EDUCATION PROGRAM General § 661.2 Who is eligible to apply for a grant under the Business and... 34 Education 3 2010-07-01 2010-07-01 false Who is eligible to apply for a grant under the Business and International Education Program? 661.2 Section 661.2 Education Regulations of the Offices of the...

  4. Developing and implementing health and sustainability guidelines for institutional food service.

    Science.gov (United States)

    Kimmons, Joel; Jones, Sonya; McPeak, Holly H; Bowden, Brian

    2012-05-01

    Health and sustainability guidelines for institutional food service are directed at improving dietary intake and increasing the ecological benefits of the food system. The development and implementation of institutional food service guidelines, such as the Health and Human Services (HHS) and General Services Administration (GSA) Health and Sustainability Guidelines for Federal Concessions and Vending Operations (HHS/GSA Guidelines), have the potential to improve the health and sustainability of the food system. Institutional guidelines assist staff, managers, and vendors in aligning the food environment at food service venues with healthier and more sustainable choices and practices. Guideline specifics and their effective implementation depend on the size, culture, nature, and management structure of an institution and the individuals affected. They may be applied anywhere food is sold, served, or consumed. Changing institutional food service practice requires comprehensive analysis, engagement, and education of all relevant stakeholders including institutional management, members of the food supply chain, and customers. Current examples of food service guidelines presented here are the HHS and GSA Health and Sustainability Guidelines for Federal Concessions and Vending Operations, which translate evidence-based recommendations on health and sustainability into institutional food service practices and are currently being implemented at the federal level. Developing and implementing guidelines has the potential to improve long-term population health outcomes while simultaneously benefitting the food system. Nutritionists, public health practitioners, and researchers should consider working with institutions to develop, implement, and evaluate food service guidelines for health and sustainability.

  5. Developing and Implementing Health and Sustainability Guidelines for Institutional Food Service123

    Science.gov (United States)

    Kimmons, Joel; Jones, Sonya; McPeak, Holly H.; Bowden, Brian

    2012-01-01

    Health and sustainability guidelines for institutional food service are directed at improving dietary intake and increasing the ecological benefits of the food system. The development and implementation of institutional food service guidelines, such as the Health and Human Services (HHS) and General Services Administration (GSA) Health and Sustainability Guidelines for Federal Concessions and Vending Operations (HHS/GSA Guidelines), have the potential to improve the health and sustainability of the food system. Institutional guidelines assist staff, managers, and vendors in aligning the food environment at food service venues with healthier and more sustainable choices and practices. Guideline specifics and their effective implementation depend on the size, culture, nature, and management structure of an institution and the individuals affected. They may be applied anywhere food is sold, served, or consumed. Changing institutional food service practice requires comprehensive analysis, engagement, and education of all relevant stakeholders including institutional management, members of the food supply chain, and customers. Current examples of food service guidelines presented here are the HHS and GSA Health and Sustainability Guidelines for Federal Concessions and Vending Operations, which translate evidence-based recommendations on health and sustainability into institutional food service practices and are currently being implemented at the federal level. Developing and implementing guidelines has the potential to improve long-term population health outcomes while simultaneously benefitting the food system. Nutritionists, public health practitioners, and researchers should consider working with institutions to develop, implement, and evaluate food service guidelines for health and sustainability. PMID:22585909

  6. Guide to federal regulation of sales of imported electricity in Canada, Mexico and the United States

    International Nuclear Information System (INIS)

    2005-01-01

    This Guide to Federal Regulation of Sales of Imported Electricity in Canada, Mexico, and the United States promotes cross-border electricity trade. It provides information on federal regulation of cross-border electricity trade and is intended to be used together with a companion guide called the North American Regulation of International Electricity Trade which outlines regulations for the construction and operation of cross-border power lines and the permitting requirements for electricity exports and imports between Canada, Mexico and the United States. The guide outlines the basic elements of the general federal regulatory process that applies to a given North American cross-border electricity trade. It offers an improved understanding of the applicable country's federal regulatory regime. Different federal government agencies within each country may regulate different aspects of a particular cross-border electricity trade. This guide does not examine the requirements that may apply at the state or provincial government levels. Rather, it is a collaborative effort of the 3 national energy departments and energy regulators that support the Experts Group on Electricity Regulatory Issues, a specialized unit assembled by the North American Energy Working Group (NAEWG). It was noted that the energy policies and regulations of each nation can change periodically

  7. Regulations and Procedures Manual

    Energy Technology Data Exchange (ETDEWEB)

    Young, Lydia J. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2011-07-25

    The purpose of the Regulations and Procedures Manual (RPM) is to provide LBNL personnel with a reference to University and Lawrence Berkeley National Laboratory (LBNL or Laboratory) policies and regulations by outlining normal practices and answering most policy questions that arise in the day-to-day operations of Laboratory organizations. Much of the information in this manual has been condensed from detail provided in LBNL procedure manuals, Department of Energy (DOE) directives, and Contract DE-AC02-05CH11231. This manual is not intended, however, to replace any of those documents. RPM sections on personnel apply only to employees who are not represented by unions. Personnel policies pertaining to employees represented by unions may be found in their labor agreements. Questions concerning policy interpretation should be directed to the LBNL organization responsible for the particular policy. A link to the Managers Responsible for RPM Sections is available on the RPM home page. If it is not clear which organization is responsible for a policy, please contact Requirements Manager Lydia Young or the RPM Editor.

  8. Regulations and Procedures Manual

    Energy Technology Data Exchange (ETDEWEB)

    Young, Lydia [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2010-09-30

    The purpose of the Regulations and Procedures Manual (RPM) is to provide Laboratory personnel with a reference to University and Lawrence Berkeley National Laboratory policies and regulations by outlining the normal practices and answering most policy questions that arise in the day-to-day operations of Laboratory departments. Much of the information in this manual has been condensed from detail provided in Laboratory procedure manuals, Department of Energy (DOE) directives, and Contract DE-AC02-05CH11231. This manual is not intended, however, to replace any of those documents. The sections on personnel apply only to employees who are not represented by unions. Personnel policies pertaining to employees represented by unions may be found in their labor agreements. Questions concerning policy interpretation should be directed to the department responsible for the particular policy. A link to the Managers Responsible for RPM Sections is available on the RPM home page. If it is not clear which department should be called, please contact the Associate Laboratory Director of Operations.

  9. Repository of Evaluation Reports

    Data.gov (United States)

    U.S. Department of Health & Human Services — To inform the HHS, Congress, and the public about the efficiency, effectiveness, and integrity of HHS programs and to recommend actions to promote those goals.

  10. 42 CFR 93.318 - Notifying ORI of special circumstances.

    Science.gov (United States)

    2010-10-01

    ... need to protect human or animal subjects. (b) HHS resources or interests are threatened. (c) Research... public prematurely so that HHS may take appropriate steps to safeguard evidence and protect the rights of...

  11. Hypnotizability, hypnosis and prepulse inhibition of the startle reflex in healthy women: an ERP analysis.

    Science.gov (United States)

    De Pascalis, Vilfredo; Russo, Emanuela

    2013-01-01

    A working model of the neurophysiology of hypnosis suggests that highly hypnotizable individuals (HHs) have more effective frontal attentional systems implementing control, monitoring performance, and inhibiting unwanted stimuli from conscious awareness, than low hypnotizable individuals (LHs). Recent studies, using prepulse inhibition (PPI) of the auditory startle reflex (ASR), suggest that HHs, in the waking condition, may show reduced sensory gating although they may selectively attend and disattend different stimuli. Using a within subject design and a strict subject selection procedure, in waking and hypnosis conditions we tested whether HHs compared to LHs showed a significantly lower inhibition of the ASR and startle-related brain activity in both time and intracerebral source localization domains. HHs, as compared to LH participants, exhibited (a) longer latency of the eyeblink startle reflex, (b) reduced N100 responses to startle stimuli, and (c) higher PPI of eyeblink startle and of the P200 and P300 waves. Hypnosis yielded smaller N100 waves to startle stimuli and greater PPI of this component than in the waking condition. sLORETA analysis revealed that, for the N100 (107 msec) elicited during startle trials, HHs had a smaller activation in the left parietal lobe (BA2/40) than LHs. Auditory pulses of pulse-with prepulse trials in HHs yielded less activity of the P300 (280 msec) wave than LHs, in the cingulate and posterior cingulate gyrus (BA23/31). The present results, on the whole, are in the opposite direction to PPI findings on hypnotizability previously reported in the literature. These results provide support to the neuropsychophysiological model that HHs have more effective sensory integration and gating (or filtering) of irrelevant stimuli than LHs.

  12. Regulations for the Safe Transport of Radioactive Materials. 1964 Revised Edition

    International Nuclear Information System (INIS)

    1965-01-01

    In 1961 the International Atomic Energy Agency, within the framework of its statutory functions and in accordance with recommendations made by its Preparatory Commission and by the Economic and Social Council of the United Nations, published safety regulations which could be applied to the national and international transport of radio active materials by all means of transport. At the same time, the Director General of the Agency indicated that these regulations would be revised at appropriate intervals in consultation with Member States and the organizations concerned and invited suggestions for their improvement in the light of experience and increased knowledge. In preparing the revised regulations presented in this document, the Agency has received considerable support from its Member States and the organizations concerned, which have made extensive studies and suggestions in order to assist in its work. The Agency also convened several meetings of experts from its Member States and of representatives of a number of international organizations, and has been represented in several meetings convened by those organizations. In publishing the revised transport regulations which result from that co-ordinated effort, the Agency aims at proposing a lasting framework of principles and rules, complemented by appropriate technical data, acceptable for the safe transport of radio active materials by air, land and water. In particular, the developments which have been introduced concerning the packaging requirements, the nuclear safety criteria for the transport of fissile materials and the methods for testing packages should facilitate the international acceptance of packages by the authorities concerned. The Board of Governors of the Agency approved the revised regulations in June and September 1964. It authorized the Director General to apply them, as appropriate, to Agency operations and Agency assisted operations and to recommend to Member States and to the

  13. Price Regulations in a Multi-unit Uniform Price Auction

    DEFF Research Database (Denmark)

    Boom, Anette

    not exceed the price cap whereas a selective bid cap for only the larger firms, does not guarantee this outcome. A sufficiently high bid floor always destroys pure strategy equilibria with equilibrium prices above the marginal costs, no matter whether the floor applies to all or only to relatively small......Inspired by recent regulations in the New York ICAP market we examine the effect of different price regulations on a multi-unit uniform price auction. We investigate a bid cap and a bid foor. Given suffciently high total capacities general bid caps always ensure that the market price does...

  14. Price Regulations in a Multi-unit Uniform Price Auction

    DEFF Research Database (Denmark)

    Boom, Anette

    Inspired by recent regulations in the New York ICAP market we examine the effect of different price regulations on a multi-unit uniform price auction. We investigate a bid cap and a bid foor. Given suffciently high total capacities general bid caps always ensure that the market price does...... not exceed the price cap whereas a selective bid cap for only the larger firms, does not guarantee this outcome. A sufficiently high bid floor always destroys pure strategy equilibria with equilibrium prices above the marginal costs, no matter whether the floor applies to all or only to relatively small...

  15. Illness Mapping: a time and cost effective method to estimate healthcare data needed to establish community-based health insurance

    Directory of Open Access Journals (Sweden)

    Binnendijk Erika

    2012-10-01

    Full Text Available Abstract Background Most healthcare spending in developing countries is private out-of-pocket. One explanation for low penetration of health insurance is that poorer individuals doubt their ability to enforce insurance contracts. Community-based health insurance schemes (CBHI are a solution, but launching CBHI requires obtaining accurate local data on morbidity, healthcare utilization and other details to inform package design and pricing. We developed the “Illness Mapping” method (IM for data collection (faster and cheaper than household surveys. Methods IM is a modification of two non-interactive consensus group methods (Delphi and Nominal Group Technique to operate as interactive methods. We elicited estimates from “Experts” in the target community on morbidity and healthcare utilization. Interaction between facilitator and experts became essential to bridge literacy constraints and to reach consensus. The study was conducted in Gaya District, Bihar (India during April-June 2010. The intervention included the IM and a household survey (HHS. IM included 18 women’s and 17 men’s groups. The HHS was conducted in 50 villages with1,000 randomly selected households (6,656 individuals. Results We found good agreement between the two methods on overall prevalence of illness (IM: 25.9% ±3.6; HHS: 31.4% and on prevalence of acute (IM: 76.9%; HHS: 69.2% and chronic illnesses (IM: 20.1%; HHS: 16.6%. We also found good agreement on incidence of deliveries (IM: 3.9% ±0.4; HHS: 3.9%, and on hospital deliveries (IM: 61.0%. ± 5.4; HHS: 51.4%. For hospitalizations, we obtained a lower estimate from the IM (1.1% than from the HHS (2.6%. The IM required less time and less person-power than a household survey, which translate into reduced costs. Conclusions We have shown that our Illness Mapping method can be carried out at lower financial and human cost for sourcing essential local data, at acceptably accurate levels. In view of the good fit of

  16. Illness Mapping: a time and cost effective method to estimate healthcare data needed to establish community-based health insurance.

    Science.gov (United States)

    Binnendijk, Erika; Gautham, Meenakshi; Koren, Ruth; Dror, David M

    2012-10-09

    Most healthcare spending in developing countries is private out-of-pocket. One explanation for low penetration of health insurance is that poorer individuals doubt their ability to enforce insurance contracts. Community-based health insurance schemes (CBHI) are a solution, but launching CBHI requires obtaining accurate local data on morbidity, healthcare utilization and other details to inform package design and pricing. We developed the "Illness Mapping" method (IM) for data collection (faster and cheaper than household surveys). IM is a modification of two non-interactive consensus group methods (Delphi and Nominal Group Technique) to operate as interactive methods. We elicited estimates from "Experts" in the target community on morbidity and healthcare utilization. Interaction between facilitator and experts became essential to bridge literacy constraints and to reach consensus.The study was conducted in Gaya District, Bihar (India) during April-June 2010. The intervention included the IM and a household survey (HHS). IM included 18 women's and 17 men's groups. The HHS was conducted in 50 villages with1,000 randomly selected households (6,656 individuals). We found good agreement between the two methods on overall prevalence of illness (IM: 25.9% ±3.6; HHS: 31.4%) and on prevalence of acute (IM: 76.9%; HHS: 69.2%) and chronic illnesses (IM: 20.1%; HHS: 16.6%). We also found good agreement on incidence of deliveries (IM: 3.9% ±0.4; HHS: 3.9%), and on hospital deliveries (IM: 61.0%. ± 5.4; HHS: 51.4%). For hospitalizations, we obtained a lower estimate from the IM (1.1%) than from the HHS (2.6%). The IM required less time and less person-power than a household survey, which translate into reduced costs. We have shown that our Illness Mapping method can be carried out at lower financial and human cost for sourcing essential local data, at acceptably accurate levels. In view of the good fit of results obtained, we assume that the method could work elsewhere

  17. PSO-RBF Neural Network PID Control Algorithm of Electric Gas Pressure Regulator

    Directory of Open Access Journals (Sweden)

    Yuanchang Zhong

    2014-01-01

    Full Text Available The current electric gas pressure regulator often adopts the conventional PID control algorithm to take drive control of the core part (micromotor of electric gas pressure regulator. In order to further improve tracking performance and to shorten response time, this paper presents an improved PID intelligent control algorithm which applies to the electric gas pressure regulator. The algorithm uses the improved RBF neural network based on PSO algorithm to make online adjustment on PID parameters. Theoretical analysis and simulation result show that the algorithm shortens the step response time and improves tracking performance.

  18. Pain Information Brochure

    Science.gov (United States)

    ... Library Health Care Systems Research Collaboratory Pain Registries IOM Report: Relieving Pain in America HHS Pathways to ... Library Health Care Systems Research Collaboratory Pain Registries IOM Report: Relieving Pain in America HHS Pathways to ...

  19. NIH Pain Consortium

    Science.gov (United States)

    ... Library Health Care Systems Research Collaboratory Pain Registries IOM Report: Relieving Pain in America HHS Pathways to ... Library Health Care Systems Research Collaboratory Pain Registries IOM Report: Relieving Pain in America HHS Pathways to ...

  20. Repository of Audit Reports

    Data.gov (United States)

    U.S. Department of Health & Human Services — To inform the HHS, Congress, and the public about the efficiency, effectiveness, and integrity of HHS programs and to recommend actions to promote those goals. To...

  1. 30 CFR 931.13 - Preemption of New Mexico laws and regulations.

    Science.gov (United States)

    2010-07-01

    ... following provisions of New Mexico law and regulation are hereby preempted and superseded as they may apply... Conservation Act (17-2-37 to 17-2-46 NMSA 1978) to the extent it is inconsistent with provisions of SMCRA...

  2. Multicriteria mapping of stakeholder preferences in regulating nanotechnology

    International Nuclear Information System (INIS)

    Hansen, Steffen Foss

    2010-01-01

    In order to facilitate stakeholder discussions on how to regulate nanotechnology, the opensource program multicriteria mapping (MCM) was used to structure 26 interviews with stakeholders in the USA. MCM offers a systematic part quantitative, part qualitative approach to clarify why some regulatory options (bans, moratoriums, voluntary measures, etc.) were deemed to be acceptable/unacceptable by various stakeholders and which criteria stakeholders used to evaluate the different regulatory options. Adopting an incremental approach and implementing a new regulatory framework was evaluated as the best options whereas a complete ban and no additional regulation of nanotechnology were found to be the least favorable. Criteria applied differed substantially among stakeholders and included social, ethical, regulatory, environmental, and health issues. Opinions on future regulation seem far less polarized than expected and it seems that stakeholders would welcome a combination of voluntary measures, an incremental approach and forming of a new regulatory framework.

  3. Multicriteria mapping of stakeholder preferences in regulating nanotechnology

    Science.gov (United States)

    Hansen, Steffen Foss

    2010-08-01

    In order to facilitate stakeholder discussions on how to regulate nanotechnology, the opensource program multicriteria mapping (MCM) was used to structure 26 interviews with stakeholders in the USA. MCM offers a systematic part quantitative, part qualitative approach to clarify why some regulatory options (bans, moratoriums, voluntary measures, etc.) were deemed to be acceptable/unacceptable by various stakeholders and which criteria stakeholders used to evaluate the different regulatory options. Adopting an incremental approach and implementing a new regulatory framework was evaluated as the best options whereas a complete ban and no additional regulation of nanotechnology were found to be the least favorable. Criteria applied differed substantially among stakeholders and included social, ethical, regulatory, environmental, and health issues. Opinions on future regulation seem far less polarized than expected and it seems that stakeholders would welcome a combination of voluntary measures, an incremental approach and forming of a new regulatory framework.

  4. Emotional and Cognitive Self-Regulation

    Directory of Open Access Journals (Sweden)

    G Matthews

    2013-12-01

    Full Text Available A brief outline of four studies that investigated interrelations of cognitive and emotional regulation in collaboration between Departments of Psychology of the University of Cincinnati and Kazakh National University is presented in this article. The aim of the first research was to examine the role of EI in regulating the affective response to a potentially threatening video and relation to brain electrical activity. The second study, conducted at the University of Cincinnati, explored the role of emotion in the search for information relevant to decision-making. The third study was devoted to the evaluating the sensitivity of a range of EEG indexes of engagement to time-on-task effects and to workload manipulation (cueing during vigilance task performance. The fourth research was based on Posner’s theory of executive control and Matthews’ theory of task engagement. Results of empirical studies has theoretical meaning in understanding selfregulation and practical value in different fields of applied psychology.

  5. Nuclear safety: economic analysis of American, French and Japanese regulations

    International Nuclear Information System (INIS)

    Leveque, Francois

    2013-05-01

    While discussing and comparing the American, Japanese and French approaches and practices, and identifying the strengths and weaknesses of each of them, the author discusses why self-regulation and civil responsibility cannot guarantee a sufficient nuclear safety level, why the safety regulation authority must be independent from industry and government, whether a figure must be put to the safety objective (for example with a risk threshold), whether it is better to define detailed standards to be applied by manufacturers and operators or to define general performance criteria to be reached

  6. Computational Investigations of Post-Transcriptional Regulation

    DEFF Research Database (Denmark)

    Rasmussen, Simon Horskjær

    and miRNA regulation was studied by cross-linking immunoprecipitation (CLIP) and RBP double knockdown experiments. A comprehensive analysis of 107 CLIP datasets of 49 RBPs demonstrated that RBPs modulate miRNA regulation. Results suggest it is mediated by RBP-binding hotspots that likely...... investigated using high-throughput data. Analysis of IMP RIP-seq, iCLIP and RNA-seq datasets identified transcripts associated with cytoplasmic IMP ribonucleoproteins. Many of these transcripts were functionally involved in actin cytoskeletal remodeling. Further analyses of this data permitted estimation...... of a bipartite motif, composed of an AU-rich and a CA-rich domain. In addition, a regulatory motif discovery method was developed and applied to identify motifs using differential expression data and CLIP-data in the above investigations. This thesis increased the understanding of the role of RBPs in mi...

  7. Applied research into direct numerical control of A-1 reactor temperature

    International Nuclear Information System (INIS)

    Karpeta, C.; Volf, K.

    1974-01-01

    Partial results of research efforts aimed at applying modern control theory in the control of the reactor of the A-1 nuclear power station are presented. A mathematical model of the process dynamics was developed. Some parameters of the model were determined using the results of an experimentally performed reactor scram. The optimal stochastic discrete regulator was determined and closed-loop transients were studied. The possibilities of implementing control routines were investigated using the RPP-16 computer. (author)

  8. 77 FR 11116 - Draft National Plan To Address Alzheimer's Disease

    Science.gov (United States)

    2012-02-24

    ... Alzheimer's Disease, which is available at http://aspe.hhs.gov/daltcp/napa/NatlPlan.shtml . DATES: Submit... Web site as soon as possible after they have been received: http://aspe.hhs.gov/daltcp/napa/#comments...

  9. 40 CFR 80.910 - How does a refiner or importer apply for a toxics baseline?

    Science.gov (United States)

    2010-07-01

    ... for a toxics baseline? 80.910 Section 80.910 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Toxics Baseline Determination § 80.910 How does a refiner or importer apply for a toxics baseline? (a)(1) A refiner or importer...

  10. Children's reflection upon the regulation of food advertising in the UK

    OpenAIRE

    Preston, Chris

    2008-01-01

    The UK is commencing with the regulation of nutritionally problematic food advertising in respect to child audiences. This applies to foods that are deemed to be excessive in salt, fat and/or sugar. The assumption is that reduced exposure to such advertising by children will reduce demand and subsequently consumption, in a bid to reduce obesity\\ud This paper concerns twelve year old children’s reflection upon the regulation of food advertising. Parents emerge as the major influence upon their...

  11. The structure, regulation, and performance of pension funds in nine industrial countries

    OpenAIRE

    Davis, E.P.; DEC

    1993-01-01

    The author offers an overview of issues relating to the development of funded pension schemes in industrial countries. The analysis applies the economic theory of pension regulation to experience with the structure, regulation, and performance of funds in nine countries - Canada, Denmark, Germany, Japan, Netherlands, Sweden, Switzerland, the United Kingdom, and the United States - seeking to shed light on the finance of old age security in developing countries and the reform of pension funds ...

  12. Soil structural quality assessment for soil protection regulation

    Science.gov (United States)

    Johannes, Alice; Boivin, Pascal

    2017-04-01

    Soil quality assessment is rapidly developing worldwide, though mostly focused on the monitoring of arable land and soil fertility. Soil protection regulations assess soil quality differently, focusing on priority pollutants and threshold values. The soil physical properties are weakly considered, due to lack of consensus and experimental difficulties faced with characterization. Non-disputable, easy to perform and inexpensive methods should be available for environmental regulation to be applied, which is unfortunately not the case. As a consequence, quantitative soil physical protection regulation is not applied, and inexpensive soil physical quality indicators for arable soil management are not available. Overcoming these limitations was the objective of a research project funded by the Swiss federal office for environment (FOEN). The main results and the perspectives of application are given in this presentation. A first step of the research was to characterize soils in a good structural state (reference soils) under different land use. The structural quality was assessed with field expertise and Visual Evaluation of the Soil Structure (VESS), and the physical properties were assessed with Shrinkage analysis. The relationships between the physical properties and the soil constituents were linear and highly determined. They represent the reference properties of the corresponding soils. In a second step, the properties of physically degraded soils were analysed and compared to the reference properties. This allowed defining the most discriminant parameters departing the different structure qualities and their threshold limits. Equivalent properties corresponding to these parameters but inexpensive and easy to determine were defined and tested. More than 90% of the samples were correctly classed with this method, which meets, therefore, the requirements for practical application in regulation. Moreover, result-oriented agri-environmental schemes for soil quality

  13. 40 CFR 86.447-2006 - What provisions apply to motorcycle engines below 50 cc that are certified under the Small SI...

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 18 2010-07-01 2010-07-01 false What provisions apply to motorcycle... Regulations for 1978 and Later New Motorcycles, General Provisions § 86.447-2006 What provisions apply to motorcycle engines below 50 cc that are certified under the Small SI program or the Recreational-vehicle...

  14. Combinatorial Cis-regulation in Saccharomyces Species

    Directory of Open Access Journals (Sweden)

    Aaron T. Spivak

    2016-03-01

    Full Text Available Transcriptional control of gene expression requires interactions between the cis-regulatory elements (CREs controlling gene promoters. We developed a sensitive computational method to identify CRE combinations with conserved spacing that does not require genome alignments. When applied to seven sensu stricto and sensu lato Saccharomyces species, 80% of the predicted interactions displayed some evidence of combinatorial transcriptional behavior in several existing datasets including: (1 chromatin immunoprecipitation data for colocalization of transcription factors, (2 gene expression data for coexpression of predicted regulatory targets, and (3 gene ontology databases for common pathway membership of predicted regulatory targets. We tested several predicted CRE interactions with chromatin immunoprecipitation experiments in a wild-type strain and strains in which a predicted cofactor was deleted. Our experiments confirmed that transcription factor (TF occupancy at the promoters of the CRE combination target genes depends on the predicted cofactor while occupancy of other promoters is independent of the predicted cofactor. Our method has the additional advantage of identifying regulatory differences between species. By analyzing the S. cerevisiae and S. bayanus genomes, we identified differences in combinatorial cis-regulation between the species and showed that the predicted changes in gene regulation explain several of the species-specific differences seen in gene expression datasets. In some instances, the same CRE combinations appear to regulate genes involved in distinct biological processes in the two different species. The results of this research demonstrate that (1 combinatorial cis-regulation can be inferred by multi-genome analysis and (2 combinatorial cis-regulation can explain differences in gene expression between species.

  15. Baseline and strategic effects behind mindful emotion regulation: behavioral and physiological investigation.

    Directory of Open Access Journals (Sweden)

    Alessandro Grecucci

    Full Text Available One of the consequences of extensive mindfulness practice is a reduction of anxiety and depression, but also a capacity to regulate negative emotions. In this study, we explored four key questions concerning mindfulness training: (1 What are the processes by which mindfulness regulates our emotions? (2 Can mindfulness be applied to social emotions? (3 Does mindfulness training affect emotionally driven behavior towards others? (4 Does mindfulness alter physiological reactivity? To address these questions, we tested, in two experiments, the ability of mindfulness meditators to regulate interpersonal emotions (Experiment 1 and interactive behaviors (Experiment 2 as compared to naïve controls. To better understand the mechanisms by which mindfulness regulates emotions, we asked participants to apply two strategies: a cognitive strategy (mentalizing, a form of reappraisal focused on the intentions of others and an experiential strategy derived from mindfulness principles (mindful detachment. Both groups were able to regulate interpersonal emotions by means of cognitive (mentalizing and experiential (mindful detachment strategies. In Experiment 1, a simple effect of meditation, independent from the implementation of the strategies, resulted in reduced emotional and physiological reactivity, as well as in increased pleasantness for meditators when compared to controls, providing evidence of baseline regulation. In Experiment 2, one visible effect of the strategy was that meditators outperformed controls in the experiential (mindful detachment but not in the cognitive (mentalize strategy, showing stronger modulation of their interactive behavior (less punishments and providing evidence of a strategic behavioral regulation. Based on these results, we suggest that mindfulness can influence interpersonal emotional reactions through an experiential mechanism, both at a baseline level and a strategic level, thereby altering the subjective and physiological

  16. Regulative environmental policy. Regulative Umweltpolitik

    Energy Technology Data Exchange (ETDEWEB)

    Goerlitz, A; Voigt, R [Universitaet der Bundeswehr Muenchen, Neubiberg (Germany, F.R.). Fakultaet fuer Sozialwissenschaften; eds.

    1991-01-01

    Regulative policy means those governmental attempts to steer the course of things which can fall back on a certain repertoire of instruments for actions in order to warrant the causal and temporal connection between the making available and the employment of means. The fact that environmental protection needs regulative policy is substantiated by the thesis that the market has failed; consequently only government can manage the public goods 'environment' in a suitable way, and it is a matter of fact that environmental protection at present is operated preferably via regulative policy. The problems of regulative enviromental policy are manifold. Its implementation often miscarries because of limited administrative resources on the one hand - making sufficient control impossible for instance -, and because of poor quality regulative instruments on the other hand. One way out would be to increase the efficiency of regulative policy by sophisticating judicial techniques. Other ways out point to the executing level and aim at improving implementation strategies or are concerned with post-regulative law. The latter refers to a new legal quality which demonstrates itself already in corporatistical crisis regulation or in induction programs such as pollution limits. A final way out favours deregulation strategies which includes the introduction of environmental levies or the allocation of environmental licences. An interdisciplinary discourse is to find out what would happen if these ways were taken. Pointers to solutions from varying scientific disciplines resulting from this discourse are to be found in this volume. (orig./HSCH).

  17. Deciphering Cis-Regulatory Element Mediated Combinatorial Regulation in Rice under Blast Infected Condition.

    Directory of Open Access Journals (Sweden)

    Arindam Deb

    Full Text Available Combinations of cis-regulatory elements (CREs present at the promoters facilitate the binding of several transcription factors (TFs, thereby altering the consequent gene expressions. Due to the eminent complexity of the regulatory mechanism, the combinatorics of CRE-mediated transcriptional regulation has been elusive. In this work, we have developed a new methodology that quantifies the co-occurrence tendencies of CREs present in a set of promoter sequences; these co-occurrence scores are filtered in three consecutive steps to test their statistical significance; and the significantly co-occurring CRE pairs are presented as networks. These networks of co-occurring CREs are further transformed to derive higher order of regulatory combinatorics. We have further applied this methodology on the differentially up-regulated gene-sets of rice tissues under fungal (Magnaporthe infected conditions to demonstrate how it helps to understand the CRE-mediated combinatorial gene regulation. Our analysis includes a wide spectrum of biologically important results. The CRE pairs having a strong tendency to co-occur often exhibit very similar joint distribution patterns at the promoters of rice. We couple the network approach with experimental results of plant gene regulation and defense mechanisms and find evidences of auto and cross regulation among TF families, cross-talk among multiple hormone signaling pathways, similarities and dissimilarities in regulatory combinatorics between different tissues, etc. Our analyses have pointed a highly distributed nature of the combinatorial gene regulation facilitating an efficient alteration in response to fungal attack. All together, our proposed methodology could be an important approach in understanding the combinatorial gene regulation. It can be further applied to unravel the tissue and/or condition specific combinatorial gene regulation in other eukaryotic systems with the availability of annotated genomic

  18. Validation of the Short Self-Regulation Questionnaire for Taiwanese College Students (TSSRQ).

    Science.gov (United States)

    Chen, Yang-Hsueh; Lin, Yu-Ju

    2018-01-01

    While self-regulation has long been recognized as an important characteristic of an individual, instruments assessing the general aptitude of self-regulation remain limited especially in Asian countries. This study re-validated Carey et al.'s (2004) Short Self-Regulation Questionnaire based on a national sample of Taiwanese college students ( N = 1,988). Item analysis, exploratory factor analysis, and confirmatory factor analysis (CFA) yielded 22 items in five internally consistent factors. Descriptive findings showed that, a lack of proactiveness and volitional control, and a decrease of self-regulation throughout the college span appeared to be an overarching problem among Taiwanese college students. Furthermore, male students achieved lower self-regulation scores than female ones, and students in Services and STEM-related majors are in the need of self-regulation enhancement. Due to the generic measurement of individual's self-regulation traits, the Taiwanese Short Self-regulation Questionnaire (TSSRQ) can be flexibly applied to various contexts and used to deal with different issues beyond learning such as college students' Internet or smartphone addiction. Through this study, we hope the validated TSSRQ can promote studies on self-regulation and associated antecedents and outcomes, in turn leveraging college students' life adjustment and well-being.

  19. Color indirect effects on melatonin regulation

    Science.gov (United States)

    Mian, Tian; Liu, Timon C.; Li, Yan

    2002-04-01

    Color indirect effect (CIE) is referred to as the physiological and psychological effects of color resulting from color vision. In previous papers, we have studied CIE from the viewpoints of the integrated western and Chinese traditional medicine, put forward the color-autonomic- nervous-subsystem model (CAM), and provided its time-theory foundation. In this paper, we applied it to study light effects on melatonin regulation in humans, and suggested that it is CIE that mediates light effects on melatonin suppression.

  20. 77 FR 33130 - Special Local Regulation; Kelley's Island Swim, Lake Erie; Kelley's Island, Lakeside, OH

    Science.gov (United States)

    2012-06-05

    ... comments by mail and would like to know that they reached the Facility, please enclose a stamped, self... vessels transiting the swim route shall proceed at a no-wake speed and maintain extra vigilance for people... regulations of Sec. 100.901 apply. Vessels transiting within the regulated area shall travel at a no-wake...

  1. The Effect Of Problem Based Learning And Self-Assessment On Students’ Writing Competency And Self-Regulated Learningm

    Directory of Open Access Journals (Sweden)

    Suyoga Dharma I Putu

    2018-01-01

    Full Text Available This experimental study aimed at investigating the effect of Problem Based Learning (PBL and self-assessment (SA on students’ writing competency and self-regulated learning in Tabanan Regency. This research applied 2x2 factorial design. 96 students were selected as sample through random sampling. Data were collected by test (writing competency and questionnaire (self-regulation. Students’ writings were scored by analytical scoring rubric. The obtained data were analyzed statistically by MANOVA at 5% significance level. This research discovers: 1 there is a significant effect of PBL which occurs simultaneously and separately on students’ writing competency and self-regulated learning, 2 there is a significant effect of SA which ocurs simultaneously and separately on students’ writing competency and self-regulated learning, 3 there is a significant interaction between teaching model and assessment type on students’ writing competency and self-regulated learning which occurs simultaneously, 4 there is no significant interaction between teaching model and assessment type on students’ writing competency, and 5 there is a significant interaction between teaching model and assessment type on students’ self-regulated learning. This research results implies that PBL and SA should be applied in instruction process as a way to improve the quality of students’ writing competency and self-regulated learning.

  2. 32 CFR 176.10 - Applicability.

    Science.gov (United States)

    2010-07-01

    ... received by HHS prior to October 25, 1994, and were spending with the Secretary of HHS on that date. These... application, but property has not been assigned or otherwise disposed of by the Military Department, the LRA...

  3. Career Development of Foreign Trained Immigrants from Regulated Professions

    Science.gov (United States)

    Novak, Lydia; Chen, Charles P.

    2013-01-01

    In this article, we aim to examine and understand the career development experiences of foreign-trained immigrants from regulated professions (FTIRPs) in Canada. To provide some background on immigration in a Canadian context, we focus on a myriad of factors that affect the vocational well-being of FTIRPs. We apply key concepts from several major…

  4. Regulations related to the transport of radioactive material in Brazil

    International Nuclear Information System (INIS)

    Sahyun, Adelia; Sordi, Gian-Maria A.A.; Sanches, Matias P.

    2001-01-01

    The transport of radioactive material has raised great interest on the part of national regulatory authorities, thus resulting in a safety measures improvement for all kinds of transportation. The transport of radioactive material is regulated by safety criteria much more than those applied to conventional hazardous material. All radioactive material transportation run in Brazilian territory must be in accordance with what is established by the CNEN-NE 5.01 - Transport of Radioactive Material. There are other national and international regulations for radioactive material transportation, which have to be accomplished with and adopted during the operation of radioactive material transportation. The aim of this paper is to verify the criteria set up in the existing regulations and propose a consensus for all the intervening organizations in the regulation process for land, air or sea transportation. This kind of transportation can not depend on the efforts of only one person, a group of workers or even any governmental body, but must be instead a shared responsibility among workers, transport firms and all regulative transportation organizations. (author)

  5. Regulations related to the transport of radioactive material in Brazil

    Energy Technology Data Exchange (ETDEWEB)

    Sahyun, Adelia; Sordi, Gian-Maria A.A. [ATOMO Radioprotecao e Seguranca Nuclear, Sao Paulo, SP (Brazil)]. E-mail: atomo@atomo.com.br; Sanches, Matias P. [Instituto de Pesquisas Energeticas e Nucleares (IPEN), Sao Paulo, SP (Brazil)]. E-mail: msanches@net.ipen.br

    2001-07-01

    The transport of radioactive material has raised great interest on the part of national regulatory authorities, thus resulting in a safety measures improvement for all kinds of transportation. The transport of radioactive material is regulated by safety criteria much more than those applied to conventional hazardous material. All radioactive material transportation run in Brazilian territory must be in accordance with what is established by the CNEN-NE 5.01 - Transport of Radioactive Material. There are other national and international regulations for radioactive material transportation, which have to be accomplished with and adopted during the operation of radioactive material transportation. The aim of this paper is to verify the criteria set up in the existing regulations and propose a consensus for all the intervening organizations in the regulation process for land, air or sea transportation. This kind of transportation can not depend on the efforts of only one person, a group of workers or even any governmental body, but must be instead a shared responsibility among workers, transport firms and all regulative transportation organizations. (author)

  6. Hip Arthroscopy Outcomes With Respect to Patient Acceptable Symptomatic State and Minimal Clinically Important Difference.

    Science.gov (United States)

    Levy, David M; Kuhns, Benjamin D; Chahal, Jaskarndip; Philippon, Marc J; Kelly, Bryan T; Nho, Shane J

    2016-09-01

    To determine whether the hip arthroscopy literature to date has shown outcomes consistent with published patient acceptable symptomatic state (PASS) and minimal clinically important difference (MCID) estimates. All clinical investigations of hip arthroscopy using modified Harris Hip Score (mHHS) and/or Hip Outcome Score (HOS) outcomes with at least 1 year of follow-up were reviewed. Ninety-one studies (9,746 hips) were included for review. Eighty-one studies (9,317 hips) contained only primary hip arthroscopies and were the primary focus of this review. The remaining studies (429 hips) did not exclude patients with prior surgical history and were thus considered separately. Mean mHHS, HOS-ADL (Activities of Daily Living) and HOS-SS (Sports-Specific) scores were compared with previously published PASS and MCID values. After 31 ± 20 months, 5.8% of study populations required revision arthroscopy and 5.5% total hip arthroplasty. A total of 88%, 25%, and 30% of study populations met PASS for mHHS, HOS-ADL, and HOS-SS, respectively, and 97%, 90%, and 93% met MCID. On bivariate analysis, increasing age was associated with significantly worse postoperative mHHS (P arthroscopy, we have found that more than 90% of study populations meet MCID standards for the most commonly used patient-reported outcomes measures in hip arthroscopy literature, mHHS and HOS. Eighty-eight percent meet PASS standards for the mHHS, but PASS standards are far more difficult to achieve for HOS-ADL (25%) and HOS-SS (30%) subscales. Differences in psychometric properties of the mHHS and HOS likely account for the discrepancies in PASS. Level IV, systematic review of Level I to IV studies. Copyright © 2016 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.

  7. Hypnotizability, hypnosis and prepulse inhibition of the startle reflex in healthy women: an ERP analysis.

    Directory of Open Access Journals (Sweden)

    Vilfredo De Pascalis

    Full Text Available A working model of the neurophysiology of hypnosis suggests that highly hypnotizable individuals (HHs have more effective frontal attentional systems implementing control, monitoring performance, and inhibiting unwanted stimuli from conscious awareness, than low hypnotizable individuals (LHs. Recent studies, using prepulse inhibition (PPI of the auditory startle reflex (ASR, suggest that HHs, in the waking condition, may show reduced sensory gating although they may selectively attend and disattend different stimuli. Using a within subject design and a strict subject selection procedure, in waking and hypnosis conditions we tested whether HHs compared to LHs showed a significantly lower inhibition of the ASR and startle-related brain activity in both time and intracerebral source localization domains. HHs, as compared to LH participants, exhibited (a longer latency of the eyeblink startle reflex, (b reduced N100 responses to startle stimuli, and (c higher PPI of eyeblink startle and of the P200 and P300 waves. Hypnosis yielded smaller N100 waves to startle stimuli and greater PPI of this component than in the waking condition. sLORETA analysis revealed that, for the N100 (107 msec elicited during startle trials, HHs had a smaller activation in the left parietal lobe (BA2/40 than LHs. Auditory pulses of pulse-with prepulse trials in HHs yielded less activity of the P300 (280 msec wave than LHs, in the cingulate and posterior cingulate gyrus (BA23/31. The present results, on the whole, are in the opposite direction to PPI findings on hypnotizability previously reported in the literature. These results provide support to the neuropsychophysiological model that HHs have more effective sensory integration and gating (or filtering of irrelevant stimuli than LHs.

  8. Knowledge, attitude, behaviour and practices (KABP) of the community and resultant IEC leading to behaviour change about dengue in Jodhpur City, Rajasthan.

    Science.gov (United States)

    2016-01-01

    In recent years dengue has been witnessed as an emerging public health problem. Therefore, the present study was undertaken in order to assess the knowledge, attitude, behaviour and practices (KABP) adopted by the society for its control and prevention. The changes in behaviour of community after imparting health education were also recorded to determine the effectiveness of information, education and communication (IEC) for dengue prevention and control in Jodhpur City of Rajasthan, India. A threefold study was conducted in Jodhpur City regarding KABP about dengue fever amongst the community. Out of 106 cases of dengue reported from Jodhpur City in the year 2008, only 20 households (HHs) could be located. Therefore, nine HHs around one dengue positive household were selected so as to cover the sample size of 200 HHs for eliciting information through structured recorded interview-schedule. Health education as provided through audiovisuals and group discussion etc. and resultant change in KABP was recorded again through interview of respondents from 100 households. Prevention from dengue mosquito bites through mats and liquid vaporizer was known to 32 and 22% HHs respectively. Inhabitants of 87% HHs preferred to visit private health facility, 85% of HHs were not aware about the symptoms of dengue, while74% HHs stated that dengue mosquito breeds in dirty water. Awareness about source of mosquito breeding and source reduction was found to be very poor, i.e. 3 and 13% which improved to 78 and 88% respectively after undertaking IEC activities. Being urban area, the economic condition and education level were somewhat similar and satisfactory in Jodhpur City. IEC resulted in significant improvement in knowledge about transmission, breeding habitats of mosquito transmitting dengue, source reduction and health treatment seeking behaviour at government facility. Through such mass awareness programmes in the communities, desired results in prevention and control of dengue

  9. Innovation in regulation of rapidly changing health markets.

    Science.gov (United States)

    Bloom, Gerald; Henson, Spencer; Peters, David H

    2014-06-24

    The rapid evolution and spread of health markets across low and middle-income countries (LMICs) has contributed to a significant increase in the availability of health-related goods and services around the world. The support institutions needed to regulate these markets have lagged behind, with regulatory systems that are weak and under-resourced. This paper explores the key issues associated with regulation of health markets in LMICs, and the different goals of regulation, namely quality and safety of care, value for money, social agreement over fair access and financing, and accountability. Licensing, price controls, and other traditional approaches to the regulation of markets for health products and services have played an important role, but they have been of questionable effectiveness in ensuring safety and efficacy at the point of the user in LMICs. The paper proposes a health market systems conceptual framework, using the value chain for the production, distribution and retail of health goods and services, to examine regulation of health markets in the LMIC context. We conclude by exploring the changing context going forwards, laying out implications for future heath market regulation. We argue that the case for new approaches to the regulation of markets for health products and services in LMICs is compelling. Although traditional "command and control" approaches will have a place in the toolkit of regulators, a broader bundle of approaches is needed that is adapted to the national and market-level context of particular LMICs. The implication is that it is not possible to apply standard or single interventions across countries, as approaches proven to work well in one context will not necessarily work well elsewhere.

  10. Measuring Sexual Orientation: A Review and Critique of U.S. Data Collection Efforts and Implications for Health Policy.

    Science.gov (United States)

    Wolff, Margaret; Wells, Brooke; Ventura-DiPersia, Christina; Renson, Audrey; Grov, Christian

    The U.S. Department of Health and Human Services' (HHS) Healthy People 2020 goals sought to improve health outcomes among sexual minorities; HHS acknowledged that a dearth of sexual orientation items in federal and state health surveys obscured a broad understanding of sexual minority-related health disparities. The HHS 2011 data progression plan aimed to advance sexual orientation data collection efforts at the national level. Sexual orientation is a complex, multidimensional construct often composed of sexual identity, sexual attraction, and sexual behavior, thus posing challenges to its quantitative and practical measurement and analysis. In this review, we (a) present existing sexual orientation constructs; (b) evaluate current HHS sexual orientation data collection efforts; (c) review post-2011 data progression plan research on sexual minority health disparities, drawing on HHS survey data; (d) highlight the importance of and (e) identify obstacles to multidimensional sexual orientation measurement and analysis; and (f) discuss methods for multidimensional sexual orientation analysis and propose a matrix for addressing discordance/branchedness within these analyses. Multidimensional sexual orientation data collection and analysis would elucidate sexual minority-related health disparities, guide related health policies, and enhance population-based estimates of sexual minority individuals to steer health care practices.

  11. Conservation voltage regulation (CVR) applied to energy savings by voltage-adjusting equipment through AMI

    Science.gov (United States)

    Lan, B.-R.; Chang, C.-A.; Huang, P.-Y.; Kuo, C.-H.; Ye, Z.-J.; Shen, B.-C.; Chen, B.-K.

    2017-11-01

    Conservation voltage reduction (CVR) includes peak demand reduction, energy conservation, carbon emission reduction, and electricity bill reduction. This paper analyzes the energy-reduction of Siwei Feeders with applying CVR, which are situated in Penghu region and equipped with smart meters. Furthermore, the applicable voltage reduction range for the feeders will be explored. This study will also investigate how the CVR effect and energy conservation are improved with the voltage control devices integrated. The results of this study can serve as a reference for the Taiwan Power Company to promote and implement voltage reduction and energy conservation techniques. This study is expected to enhance the energy-reduction performance of the Penghu Low Carbon Island Project.

  12. Design of Current-Controller with PR-regulator for LCL-Filter Based Grid-Connected Converter

    DEFF Research Database (Denmark)

    Zeng, Guohong; Rasmussen, Tonny Wederberg

    2010-01-01

    In the application of LCL-filter based converters, the structure and parameters of current-controller is very important for the system stability and output current quality. This paper presents a filter-capacitor current feedback control scheme for grid-connected converter. The controller...... is consisted of a proportional-resonance regulator and a proportional regulator. Unlike the existing control strategy with unit capacitor current feedback, the proposed method applies the proportional regulator to the feedback path, which can decouple these two regulators, and simplify the tuning process...... of the control strategy and the proposed current controller design method are verified by the simulation results of a 50kVA grid-connected inverter....

  13. ER-16 regulation. Requirements for granting the permit exceptional use of medical devices in humans

    International Nuclear Information System (INIS)

    2015-01-01

    The purpose of this regulation is to establish requirements for applying for a permit exceptional use of medical equipment in Human Beings, the procedures for the evaluation process and bestowal. This regulation is aimed at researchers and designers of medical equipment, related to or associated with National Health Service's priority programs of interest to health.

  14. The effects of average revenue regulation on electricity transmission investment and pricing

    International Nuclear Information System (INIS)

    Matsukawa, Isamu

    2008-01-01

    This paper investigates the long-run effects of average revenue regulation on an electricity transmission monopolist who applies a two-part tariff comprising a variable congestion price and a non-negative fixed access fee. A binding constraint on the monopolist's expected average revenue lowers the access fee, promotes transmission investment, and improves consumer surplus. In a case of any linear or log-linear electricity demand function with a positive probability that no congestion occurs, average revenue regulation is allocatively more efficient than a Coasian two-part tariff if the level of capacity under average revenue regulation is higher than that under a Coasian two-part tariff. (author)

  15. 78 FR 54571 - Special Local Regulation for Marine Event Hampton Bay Days Festival, Hampton River; Hampton, VA

    Science.gov (United States)

    2013-09-05

    ...-AA08 Special Local Regulation for Marine Event Hampton Bay Days Festival, Hampton River; Hampton, VA... Fifth Coast Guard District. This regulation applies only to the Hampton Bay Days Festival, which... Purpose Hampton Bay Days is sponsoring the three days Hampton Bay Days Festival, which includes a...

  16. Apply or Not to Apply, That Is The Question: Sustainable Development as Solution to the Antinomy About the Application of the New Forest Code

    Directory of Open Access Journals (Sweden)

    Rafael Antonietti Matthes

    2016-10-01

    Full Text Available Starting from the Brazilian constitutional premise, through which, economic development, and social development, should strive for maintaining environmental quality for present and future generations (Article 225, heading, this study suggests a possible indicator to resolve the contradiction related to the applicability or otherwise of the new Forest Code (Law 12651 of May 25, 2012 to the terms of adjustment of conduct signed before its term, which agreed obligations should be implemented upon its validity. Apply or not apply, that is the question. On the one hand, postulate in favor of the fence thesis environmental backlash on the other, there is the provision of incentives such as propulsion protective behaviors and the factual social effectiveness of current regulations now. Using the methods of dialectical and systemic approach, with empirical notes, lists up the fundamental right to sustainable development as respond to the contrast of the legal language indicated in the methodological problem.

  17. Voltage-regulating constant-current sources in a linear induction accelerator

    International Nuclear Information System (INIS)

    Zhao Juan; Cao Kefeng; Deng Jianjun; Zhu Lijun; Yang Jia; Ye Chao; Huang Bin; Cao Ningxiang; Dong Jinxuan; Zhang Jichang; Yu Zhiguo; Chen Min

    2002-01-01

    Constant-current Sources are one of key units in a linear induction accelerator. The requirements for the sources are to supply stable direct current of high power for the induction coil, be easy to computer-control and highly stable and reliable. Applying the technique of linear current source regulating in series, the primary voltage of the power transformer is regulated through an MJYS-JL-350A type three-phase alterative voltage-regulating module. The output current variation is 300-500 A when the load variation is 0.06-0.1 Ω and the voltage drop of the regulator tube is controlled within 8 V±2V when the variation of mains voltage is in ±10%. Both the current ripple and stability meet the technical requirements. The constant-current sources are controlled through an industrial controller. For each of the constant-current sources has a smallest system comprised of 8051 which is communication-controlled through a RS-485 interface, the sources can be controlled remotely

  18. Convergence of Romanian accounting regulations with IFRS. A longitudinal analysis

    Directory of Open Access Journals (Sweden)

    Ioana PĂLĂRIE

    2016-06-01

    Full Text Available In this paper we analyse the evolution in the level of convergence of the Romanian accounting regulations with IFRS in the last decade. We focus our study on the accounting topics covered by IAS16, IAS17, IAS 41 and SIC15. We find that in 2005 the regulations exhibit a good level of convergence for property, plant and equipment, a medium level of convergence for lease accounting and divergence for accounting for the agricultural activity. The overall convergence level improved over time for all the topics analysed. These results indicate that the companies with dual reporting may incur lower costs in applying IFRS. Moreover, the national regulations offer the opportunity for a higher level of comparability in Romania of the financial statements prepared under IFRS with those prepared under national regulations. However, we underline that the institutional factors (such as the tax influence over accounting might negatively affect the convergence of practices.

  19. Understanding Regulation of Metabolism through Feasibility Analysis

    Science.gov (United States)

    Nikerel, Emrah; Berkhout, Jan; Hu, Fengyuan; Teusink, Bas; Reinders, Marcel J. T.; de Ridder, Dick

    2012-01-01

    Understanding cellular regulation of metabolism is a major challenge in systems biology. Thus far, the main assumption was that enzyme levels are key regulators in metabolic networks. However, regulation analysis recently showed that metabolism is rarely controlled via enzyme levels only, but through non-obvious combinations of hierarchical (gene and enzyme levels) and metabolic regulation (mass action and allosteric interaction). Quantitative analyses relating changes in metabolic fluxes to changes in transcript or protein levels have revealed a remarkable lack of understanding of the regulation of these networks. We study metabolic regulation via feasibility analysis (FA). Inspired by the constraint-based approach of Flux Balance Analysis, FA incorporates a model describing kinetic interactions between molecules. We enlarge the portfolio of objectives for the cell by defining three main physiologically relevant objectives for the cell: function, robustness and temporal responsiveness. We postulate that the cell assumes one or a combination of these objectives and search for enzyme levels necessary to achieve this. We call the subspace of feasible enzyme levels the feasible enzyme space. Once this space is constructed, we can study how different objectives may (if possible) be combined, or evaluate the conditions at which the cells are faced with a trade-off among those. We apply FA to the experimental scenario of long-term carbon limited chemostat cultivation of yeast cells, studying how metabolism evolves optimally. Cells employ a mixed strategy composed of increasing enzyme levels for glucose uptake and hexokinase and decreasing levels of the remaining enzymes. This trade-off renders the cells specialized in this low-carbon flux state to compete for the available glucose and get rid of over-overcapacity. Overall, we show that FA is a powerful tool for systems biologists to study regulation of metabolism, interpret experimental data and evaluate hypotheses. PMID

  20. Interactions of artificial lakes with groundwater applying an integrated MODFLOW solution

    Science.gov (United States)

    El-Zehairy, A. A.; Lubczynski, M. W.; Gurwin, J.

    2018-02-01

    Artificial lakes (reservoirs) are regulated water bodies with large stage fluctuations and different interactions with groundwater compared with natural lakes. A novel modelling study characterizing the dynamics of these interactions is presented for artificial Lake Turawa, Poland. The integrated surface-water/groundwater MODFLOW-NWT transient model, applying SFR7, UZF1 and LAK7 packages to account for variably-saturated flow and temporally variable lake area extent and volume, was calibrated throughout 5 years (1-year warm-up, 4-year simulation), applying daily lake stages, heads and discharges as control variables. The water budget results showed that, in contrast to natural lakes, the reservoir interactions with groundwater were primarily dependent on the balance between lake inflow and regulated outflow, while influences of precipitation and evapotranspiration played secondary roles. Also, the spatio-temporal lakebed-seepage pattern was different compared with natural lakes. The large and fast-changing stages had large influence on lakebed-seepage and water table depth and also influenced groundwater evapotranspiration and groundwater exfiltration, as their maxima coincided not with rainfall peaks but with highest stages. The mean lakebed-seepage ranged from 0.6 mm day-1 during lowest stages (lake-water gain) to 1.0 mm day-1 during highest stages (lake-water loss) with largest losses up to 4.6 mm day-1 in the peripheral zone. The lakebed-seepage of this study was generally low because of low lakebed leakance (0.0007-0.0015 day-1) and prevailing upward regional groundwater flow moderating it. This study discloses the complexity of artificial lake interactions with groundwater, while the proposed front-line modelling methodology can be applied to any reservoir, and also to natural lake interactions with groundwater.

  1. Emotion Regulation from Early Adolescence to Emerging Adulthood and Middle Adulthood: Age Differences, Gender Differences, and Emotion-Epecific Developmental Variations

    Science.gov (United States)

    Zimmermann, Peter; Iwanski, Alexandra

    2014-01-01

    Despite the growing research on emotion regulation, the empirical evidence for normative age-related emotion regulation patterns is rather divergent. From a life-span perspective, normative age changes in emotion regulation may be more salient applying the same methodological approach on a broad age range examining both growth and decline during…

  2. Building confidence in nuclear waste regulation: how NRC is adapting in response to stakeholder concerns

    International Nuclear Information System (INIS)

    Kotra, Janet P.

    2004-01-01

    Increasing public confidence in the U.S. Nuclear Regulatory Commission as an effective and independent regulator is an explicit goal of the Agency. When developing new, site-specific regulations for the proposed geologic repository at Yucca Mountain, Nevada, NRC sought to improve its efforts to inform and involve the public in NRC's decision-making process. To this end, NRC has made, and continues to make significant organizational, process and policy changes. NRC successfully applied these changes as it completed final regulations for Yucca Mountain, when introducing a draft license review plan for public comment, and when responding to public requests for information on NRC's licensing and hearing process. It should be understood, however, that these changes emerged, and continue to be applied, in the context of evolving agency concern for increasing stakeholder confidence reflected in institutional changes within the agency as a whole. (author)

  3. Regulating antifouling paints for leisure boats - a patchwork of rules across three Baltic Sea countries

    DEFF Research Database (Denmark)

    Kymenvaara, Sara; Anker, Helle Tegner; Baaner, Lasse

    2017-01-01

    This article analyses how the use of antifouling paints for leisure boats is regulated in Denmark, Finland and Sweden. All three countries appear to apply a somewhat fragmented approach to the different matters related to antifouling paints, including environmental quality (e.g. water quality...... sufficient measures and conduct. Environmental protection regulation, including waste legislation, generally excludes smaller leisure boat marinas and boat clubs from permitting and waste management requirements. In product regulation, the authorisation and/or restriction rules of antifouling paints...

  4. 78 FR 16622 - Gulf of the Farallones and Monterey Bay National Marine Sanctuaries Regulations on Introduced...

    Science.gov (United States)

    2013-03-18

    ... any organism that has been genetically modified (15 CFR 922.81). This final rule, combined with a... not apply if NOAA were willing and able to modify its regulations to except (i.e., allow) all state... Governor's concerns that would also meet NOAA's goals. For GFNMS, NOAA proposed to modify the regulations...

  5. Petroleum products price regulation in Nov Scotia : a six-month review

    International Nuclear Information System (INIS)

    2007-03-01

    Gasoline pricing regulation was introduced in July 2006 in order to achieve the following 3 main objectives: (1) stabilize prices by reducing the frequency of price changes and creating more uniform pricing across the province, (2) maintain industry infrastructure by slowing or halting the decline in the dealer network, particularly in rural areas, by improving viability through regulated margins, and (3) minimize the cost to consumers since higher prices are expected to result from the actions needed to maintain price stability and the higher margins needed to maintain industry infrastructure. This report examined the extent to which these objectives were achieved and contained the findings and recommendations of a review of the first six months of gasoline price regulation in Nova Scotia. The report discussed the rationale for regulation, study objectives, approach, and warning signs. It also discussed gasoline regulation in Nova Scotia including how regulation works and implementing regulation. The Nova Scotia gasoline market was presented with reference to industry structure; pre-regulation competition and pricing; and how regulation may affect structure and competition. Last, the report discussed whether regulation was meeting the objectives and perspectives on regulation. Several recommendations were presented, such as reducing the benchmark price adjustment period from two weeks to one week; removing the price cap on full-serve gasoline; adopting a fixed and transparent formula for forward averaging and applying it at each adjustment; and considering a framework for regulatory review. 12 refs., 15 figs

  6. The ionising radiation (medical exposure) regulations - IR (ME) R, Malta

    International Nuclear Information System (INIS)

    Desai, R.; Brejza, P.; Cremona, J.

    2004-01-01

    Full text: The regulations in Malta at present are in draft stage. These regulations partially implement European Council Directive 97/43/Euratom. This Directive lays down the basic measurements for the health and protection of individuals against dangers of ionising radiation in relation to medical exposure. The regulations impose duties on persons administering radiations, to protect people from unnecessary exposure whether as part of their own medical diagnosis, treatment or as part of occupational health worker for health screening, medico-legal procedures, voluntary participation in research etc. These regulations also apply to individuals who help other individuals undergoing medical exposure. Main provisions 1. Regulation 2 contains the definitions of 28 terms used in these regulations. 2. Regulation 3.1 and 3.2 sets out the medical exposures to which the regulations apply. 3. Regulation 4 requires approval of medical exposures due to medical research, from radiation protection board of Malta. 4. Regulation 5 prohibits new procedures involving medical exposure unless it has been justified in advance. 5. Regulation 6 provides conditions justifying medical exposures. It prohibits any medical exposure from being carried out which has not been justified and authorized and sets out matters to be taken into account for justification. 6. Regulation 7 requires that practitioner justifies the exposure, shall pay special attention towards (a) exposure from medical research procedures where there is no direct health benefit to the individual undergoing exposure, (b) exposures for medico-legal purposes; (c) exposures to pregnant or possible pregnant women and (d) exposures to breast-feeding women. 7. Regulation 8.1 to 8.3 prohibit any medical exposure from being carried out which has not been justified and sets out matters to be taken for justification 8. Regulation 8.4 prohibits an exposure if it cannot be justified. 9. Regulation 9 requires the employer to provide a

  7. Counterbalancing the use of ultrasound contrast agents by a cavitation-regulated system.

    Science.gov (United States)

    Desjouy, C; Fouqueray, M; Lo, C W; Muleki Seya, P; Lee, J L; Bera, J C; Chen, W S; Inserra, C

    2015-09-01

    The stochastic behavior of cavitation can lead to major problems of initiation and maintenance of cavitation during sonication, responsible of poor reproducibility of US-induced bioeffects in the context of sonoporation for instance. To overcome these disadvantages, the injection of ultrasound contrast agents as cavitation nuclei ensures fast initiation and lower acoustic intensities required for cavitation activity. More recently, regulated-cavitation devices based on the real-time modulation of the applied acoustic intensity have shown their potential to maintain a stable cavitation state during an ultrasonic shot, in continuous or pulsed wave conditions. In this paper is investigated the interest, in terms of cavitation activity, of using such regulated-cavitation device or injecting ultrasound contrast agents in the sonicated medium. When using fixed applied acoustic intensity, results showed that introducing ultrasound contrast agents increases reproducibility of cavitation activity (coefficient of variation 62% and 22% without and with UCA, respectively). Moreover, the use of the regulated-cavitation device ensures a given cavitation activity (coefficient of variation less 0.4% in presence of UCAs or not). This highlights the interest of controlling cavitation over time to free cavitation-based application from the use of UCAs. Interestingly, during a one minute sonication, while ultrasound contrast agents progressively disappear, the regulated-cavitation device counterbalance their destruction to sustain a stable inertial cavitation activity. Copyright © 2015 Elsevier B.V. All rights reserved.

  8. Impacts of hazardous waste regulation on low-level waste management

    International Nuclear Information System (INIS)

    Sharples, F.E.; Eyman, L.D.

    1987-01-01

    Since passage of the 1984 amendments to the Resource Conservation and Recovery Act (RCRA), major changes have occurred in the regulation of hazardous waste. The US Environmental Protection Agency (EPA) has also greatly modified its interpretation of how these regulations apply to wastes from federal facilities, including defense wastes from US Department of Energy (DOE) sites. As a result, the regulatory distinctions between low-level radioactive waste (LLW) and hazardous waste are becoming blurred. This paper discusses recent statutory and regulatory changes and how they might affect the management of LLW at DOE facilities. 6 references

  9. 41 CFR 102-74.330 - What smoking restrictions apply to outside areas under Executive branch control?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What smoking restrictions apply to outside areas under Executive branch control? 102-74.330 Section 102-74.330 Public... MANAGEMENT REGULATION REAL PROPERTY 74-FACILITY MANAGEMENT Facility Management Smoking § 102-74.330 What...

  10. Federal Aviation Regulations - National Aviation Regulations of Russia

    Science.gov (United States)

    Chernykh, O.; Bakiiev, M.

    2018-03-01

    Chinese Aerospace Engineering is currently developing cooperation with Russia on a wide-body airplane project that has directed the work towards better understanding of Russian airworthiness management system. The paper introduces national Aviation regulations of Russia, presents a comparison of them with worldwide recognized regulations, and highlights typical differences. They have been found to be: two general types of regulations used in Russia (Aviation Regulations and Federal Aviation Regulations), non-unified structure of regulations on Aircraft Operation management, various separate agencies responsible for regulation issuance instead of one national aviation authority, typical confusions in references. The paper also gives a list of effective Russian Regulations of both types.

  11. Framework for applying RI-ISI methodology for Indian PHWRs

    International Nuclear Information System (INIS)

    Vinod, Gopika; Saraf, R.K.; Ghosh, A.K.; Kushwaha, H.S.

    2006-01-01

    Risk Informed In-Service Inspection (RI-ISI) aims at categorizing the components for In-Service inspection based on their contribution to Risk. For defining the contribution of risk from components, their failure probabilities and its subsequent effect on Core Damage Frequency (CDF) needs to be evaluated using Probabilistic Safety Assessment methodology. During the last several years, both the U.S. Nuclear Regulatory Commission (NRC) and the nuclear industry have recognized that Probabilistic Safety Assessment (PSA) has evolved to be more useful in supplementing traditional engineering approaches in reactor regulation. The paper highlights the various stages involved in applying RI-ISI and then compares the findings with existing ISI practices. (author)

  12. Effect of growth regulators application on the quality maintenance of 'Brookfield' apples

    Directory of Open Access Journals (Sweden)

    Auri Brackmann

    2015-01-01

    Full Text Available AbstractThe main goal of the present study was to elucidate the effect of growth regulators at harvest and postharvest quality of 'Brookfield' apples stored under controlled atmosphere through a multivariate approach. Thus, an experiment with two steps (field and storage was carried out. The treatments in field were applied with an output of 1,000 L ha–1 of water. The following treatments were tested: Control: only water application; AVG (aminoethoxyvinylglycine: 0.83 kg ha–1 of Retain® applied 30 days before harvest (BH; NAA (naphthalene acetic acid: 40g ha–1of naphthalene acetic acid applied 7 days BH; Ethephon: 2.0 L ha–1 of Ethrel® applied 10 days BH; 1-MCP: 0.625µL L–1 of 1-MCP (1-methylcyclopropene: applied during postharvest (storage; LE (low ethylene: with the allocation of potassium permanganate sachets during postharvest. Fruits treated with AVG in the field showed an opposite response to the fruits with NAA. AVG application followed by another growth regulator (AVG + Ethephon and AVG + NAA showed an advance in maturation, nearing these fruits to the control treatment, this effect is likely related to the higher ethylene production by these fruits compared to fruits with AVG alone. AVG, 1-MCP and LE kept a similar response on quality maintenance. Ethephon application prevented the negative effect of NAA at harvest, but after storage, the combined NAA + ethephon application increased the physiological disorders, reducing internal quality.

  13. Rehabilitation of executive functioning with training in attention regulation applied to individually defined goals: a pilot study bridging theory, assessment, and treatment.

    Science.gov (United States)

    Novakovic-Agopian, Tatjana; Chen, Anthony J-W; Rome, Scott; Abrams, Gary; Castelli, Holli; Rossi, Annemarie; McKim, Ryan; Hills, Nancy; D'Esposito, Mark

    2011-01-01

    To assess feasibility and effects of training in goal-oriented attentional self-regulation for patients with brain injury and chronic executive dysfunction. Sixteen individuals with chronic brain injury and mild to moderate executive dysfunction. Participants were divided into 2 groups: one group completed goal-oriented attentional self-regulation training during the first 5 weeks, followed by a brief (2-hour) educational instruction session as a control midway through the second 5 weeks; the other group participated in reverse order. Neuropsychological and functional performance assessed at baseline and at weeks 5 and 10. Participants found training in goal-oriented attentional self-regulation engaging, incorporated some trained strategies into daily life, and reported subjective improvements in personal functioning. At week 5, participants who completed goals training significantly improved on tests of attention and executive function and had fewer functional task failures, while performance did not change after educational instruction. At week 10, participants who crossed over from educational instruction to goals training also significantly improved on attention and executive function tests. Participants who crossed from goals training to educational instruction maintained their week 5 gains. Training in goal-oriented attentional self-regulation is theoretically driven and feasible in a research setting. Pilot results suggest improvements in cognitive and functional domains targeted by the intervention.

  14. Illicit drugs policy through the lens of regulation.

    Science.gov (United States)

    Ritter, Alison

    2010-07-01

    The application of regulatory theory to the problem of illicit drugs has generally been thought about only in terms of 'command and control'. The international treaties governing global illicit drug control and the use of law enforcement to dissuade and punish offenders have been primary strategies. In this paper I explore the application of other aspects of regulatory theory to illicit drugs-primarily self-regulation and market regulation. There has been an overreliance on strategies from the top of the regulatory pyramid. Two other regulatory strategies--self-regulation and market regulation--can be applied to illicit drugs. Self-regulation, driven by the proactive support of consumer groups may reduce drug-related harms. Market strategies such as pill-testing can change consumer preferences and encourage alternate seller behaviour. Regulatory theory is also concerned with partnerships between the state and third parties: strategies in these areas include partnerships between police and pharmacies regarding sale of potential precursor chemicals. Regulatory theory and practice is a rich and well-developed field in the social sciences. I argue that governments should consider the full array of regulatory strategies. Using regulatory theory provides a rationale and justification to strategies that are currently at the whim of politics, such as funding for user groups. The greater application of regulatory approaches may produce more flexible and structured illicit drug policies. Copyright (c) 2009 Elsevier B.V. All rights reserved.

  15. Impact of regulation and supervision on European banks’ stability

    Directory of Open Access Journals (Sweden)

    Faten Ben Bouheni

    2014-03-01

    Full Text Available This article applies the Generalized Method of Moments technique for dynamic panels, using bank-level data for the selected European countries over the period 2005 to 2011, to investigate the impact of regulation and supervision on risk taking. Three conclusions are reached. First, in France, Germany and UK, restriction on bank activities boosts banking stability. However, supervisors’ power and capital adequacy encourage risk taking. Second, in Italy, Greece and Spain, we find that with more supervisors’ power, largest banks tend to take greater risks and strengthening regulation and supervision weakens the bank’s stability. However, the capital requirements decrease the risk taking. Third, strengthening regulatory and supervisory framework, and compliance with Basel principles enhance financial stability in Europe. These different results between European countries show that the application of regulation and supervision depends on the monitoring mode and the rhythm of application of regulatory policies

  16. [Performance based regulation: a strategy to increase breastfeeding rates].

    Science.gov (United States)

    Cobo-Armijo, Fernanda; Charvel, Sofía; Hernández-Ávila, Mauricio

    2017-01-01

    The decreasing breastfeeding rate in México is of public health concern. In this paper we discus an innovative regulatory approach -Performance Based Regulation- and its application to improve breastfeeding rates. This approach, forces industry to take responsibility for the lack of breastfeeding and its consequences. Failure to comply with this targets results in financial penalties. Applying performance based regulation as a strategy to improve breastfeeding is feasible because: the breastmilk substitutes market is an oligopoly, hence it is easy to identify the contribution of each market participant; the regulation's target population is clearly defined; it has a clear regulatory standard which can be easily evaluated, and sanctions to infringement can be defined under objective parameters. modify public policy, celebrate concertation agreements with the industry, create persuasive sanctions, strengthen enforcement activities and coordinate every action with the International Code of Marketing of Breast-milk Substitutes.

  17. Sonoporation of adherent cells under regulated ultrasound cavitation conditions.

    Science.gov (United States)

    Muleki Seya, Pauline; Fouqueray, Manuela; Ngo, Jacqueline; Poizat, Adrien; Inserra, Claude; Béra, Jean-Christophe

    2015-04-01

    A sonoporation device dedicated to the adherent cell monolayer has been implemented with a regulation process allowing the real-time monitoring and control of inertial cavitation activity. Use of the cavitation-regulated device revealed first that adherent cell sonoporation efficiency is related to inertial cavitation activity, without inducing additional cell mortality. Reproducibility is enhanced for the highest sonoporation rates (up to 17%); sonoporation efficiency can reach 26% when advantage is taken of the standing wave acoustic configuration by applying a frequency sweep with ultrasound frequency tuned to the modal acoustic modes of the cavity. This device allows sonoporation of adherent and suspended cells, and the use of regulation allows some environmental parameters such as the temperature of the medium to be overcome, resulting in the possibility of cell sonoporation even at ambient temperature. Copyright © 2015 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.

  18. Applying the de minimis concept to mixed wastes

    International Nuclear Information System (INIS)

    Davis, J.P.; Chan, D.W.; Wofford, B.R.

    1988-01-01

    In recent years, a concept of de minimis, below regulatory concern, threshold, or negligible levels of radiation dose and risk from low level waste has begun to be accepted by standard setting and regulatory bodies throughout the world, including ICRP, NCRP, IAEA, USNRC, USDOE, USEPA, and UKNRPB. Moreover, the de minimus principle has long been recognized by the courts and has been applied in the area of environmental health and industrial hygiene law. This paper reviews the precidence in these areas and addresses the reasonableness of establishing BRC levels for chemical, as well as radiological constituents of mixed wastes, in order to minimize the quantity of true mixed wastes that must be disposed of under a duel regulatory system. A two-tiered BRC approach is proposed, which would recognize that since waste deregulated for one of the constituents would still be strictly controlled, there could be conditional BRC levels established higher than those that would apply to cases where disposal of deregulated waste is essentially uncontrolled. This paper discusses some of the technical and trans-scientific concerns involved in implementing the BRC approach in the high profile world of environmental regulation

  19. Evaluation of the Changes in the Regulation of Secondary Education Institutions According to Teachers' Viewpoints (Turkey)

    Science.gov (United States)

    Coskun, Mucahit; Sozen, Erol

    2017-01-01

    The purpose of this study is to evaluate teachers' viewpoints about the changes made in the regulation of passing lesson at schools, which became active in 2013 to 2014 academic year. The pass grade applied depends on this regulation, common exams, shortening of the absenteeism durations, and assigning students with performance tasks according to…

  20. Validation of the Short Self-Regulation Questionnaire for Taiwanese College Students (TSSRQ

    Directory of Open Access Journals (Sweden)

    Yang-Hsueh Chen

    2018-03-01

    Full Text Available While self-regulation has long been recognized as an important characteristic of an individual, instruments assessing the general aptitude of self-regulation remain limited especially in Asian countries. This study re-validated Carey et al.'s (2004 Short Self-Regulation Questionnaire based on a national sample of Taiwanese college students (N = 1,988. Item analysis, exploratory factor analysis, and confirmatory factor analysis (CFA yielded 22 items in five internally consistent factors. Descriptive findings showed that, a lack of proactiveness and volitional control, and a decrease of self-regulation throughout the college span appeared to be an overarching problem among Taiwanese college students. Furthermore, male students achieved lower self-regulation scores than female ones, and students in Services and STEM-related majors are in the need of self-regulation enhancement. Due to the generic measurement of individual's self-regulation traits, the Taiwanese Short Self-regulation Questionnaire (TSSRQ can be flexibly applied to various contexts and used to deal with different issues beyond learning such as college students' Internet or smartphone addiction. Through this study, we hope the validated TSSRQ can promote studies on self-regulation and associated antecedents and outcomes, in turn leveraging college students' life adjustment and well-being.

  1. 76 FR 4463 - Privacy Act of 1974; Report of Modified or Altered System of Records

    Science.gov (United States)

    2011-01-25

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Privacy Act of... Program Records, HHS/CDC/NIOSH.'' HHS is proposing to add the following Breach Response Routine Use... and responding to the Breach of Personally Identifiable Information: [[Page 4464

  2. 76 FR 4443 - Privacy Act of 1974; Report of Modified or Altered System of Records

    Science.gov (United States)

    2011-01-25

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Privacy Act of... Health Benefit Recipients, HHS/CDC/NCHSTP.'' HHS is proposing to add the following Breach Response..., Safeguarding Against and Responding to the Breach of Personally Identifiable Information. To appropriate...

  3. One year's experience by COGEMA logistics of application of the new modal regulations

    International Nuclear Information System (INIS)

    Malesys, P.

    2002-01-01

    International transport of radioactive materials is regulated by international and regional modal regulations that apply to all dangerous goods. The requirements for radioactive materials in the modal regulations are based on those of the 'Regulations for the Safe Transport of Radioactive Material' set forth by the International Atomic Energy Agency (IAEA). The last edition of the IAEA regulations was published in 1996 (TS-R-1 (ST-1, Revised)), then incorporated in the modal regulations, and finally implemented, with various transitional periods throughout 2001. As a final result, since 1 January 2002 it has been mandatory, for all modes, to perform transports in accordance with the 1996 edition of the IAEA transport regulations. In the mean time, all the international and regional regulations have also been reformatted, and each of them has now adopted the unified format of the United Nations 'Recommendations on the Transport of Dangerous Goods - Model Regulations', often referred to as the Orange Book. This paper presents the experience of COGEMA Logistics with the application of this new set of regulations to design of packages, transport operations, and administrative matters. Both the advantages provided by these new regulations and the difficulties which were (and are still being) met are presented. (author)

  4. Self-Regulation, Self-Efficacy and Health Behavior Change in Older Adults.

    Science.gov (United States)

    Purdie, Nola; McCrindle, Andrea

    2002-01-01

    Presents an overview of self-regulation models: theory of planned behavior, protection motivation theory, health belief model, action control theory, transtheoretical model of behavior change, health action process, and precaution adoption process. Applies models to health behavior change in older adults with cardiovascular disease or diabetes.…

  5. Recurrent Hypothenar Hammer Syndrome: A Case Report.

    Science.gov (United States)

    Adams, Nicholas S; Ford, Ronald D

    2016-10-01

    Hypothenar hammer syndrome (HHS) is a rare cause of digital ischemia and pain caused from repetitive trauma to the palm. Often related to occupational practices, thrombosis and embolization can occur. Treatment is often surgical and involves excision with or without reconstruction. We describe a 55 year-old, male pipe fitter previously diagnosed and treated for HHS with excision and repair using a reversed interpositional vein graft in the mid-1980's. He continued to work in the profession, which he regularly used his palm as a hammer and returned approximately 30 years later with recurrent symptoms of cold intolerance and pain. Angiography confirmed occlusion of the ulnar artery with emboli present distally. The patient was again treated with excision and reconstruction. HHS is an uncommon cause of digital ischemia. Its recurrence is even more rare. To our knowledge, this is the first described case of diagnosed and treated recurrent HHS.

  6. Optimal experimental design in an epidermal growth factor receptor signalling and down-regulation model.

    Science.gov (United States)

    Casey, F P; Baird, D; Feng, Q; Gutenkunst, R N; Waterfall, J J; Myers, C R; Brown, K S; Cerione, R A; Sethna, J P

    2007-05-01

    We apply the methods of optimal experimental design to a differential equation model for epidermal growth factor receptor signalling, trafficking and down-regulation. The model incorporates the role of a recently discovered protein complex made up of the E3 ubiquitin ligase, Cbl, the guanine exchange factor (GEF), Cool-1 (beta -Pix) and the Rho family G protein Cdc42. The complex has been suggested to be important in disrupting receptor down-regulation. We demonstrate that the model interactions can accurately reproduce the experimental observations, that they can be used to make predictions with accompanying uncertainties, and that we can apply ideas of optimal experimental design to suggest new experiments that reduce the uncertainty on unmeasurable components of the system.

  7. 21 CFR 1.382 - What labeling or marking requirements apply to a detained article of food?

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false What labeling or marking requirements apply to a detained article of food? 1.382 Section 1.382 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL GENERAL ENFORCEMENT REGULATIONS Administrative Detention of Food for...

  8. 48 CFR 32.405 - Applying Pub. L. 85-804 to advance payments under sealed bid contracts.

    Science.gov (United States)

    2010-10-01

    ... advance payments under sealed bid contracts. 32.405 Section 32.405 Federal Acquisition Regulations System... Non-Commercial Items 32.405 Applying Pub. L. 85-804 to advance payments under sealed bid contracts. (a... provisions of law relating to contracts, as explained in 50.101-1(a), also include making advance payments...

  9. Improved wound management by regulated negative pressure-assisted wound therapy and regulated, oxygen- enriched negative pressure-assisted wound therapy through basic science research and clinical assessment

    Directory of Open Access Journals (Sweden)

    Moris Topaz

    2012-01-01

    Full Text Available Regulated negative pressure-assisted wound therapy (RNPT should be regarded as a state-of-the-art technology in wound treatment and the most important physical, nonpharmaceutical, platform technology developed and applied for wound healing in the last two decades. RNPT systems maintain the treated wound′s environment as a semi-closed, semi-isolated system applying external physical stimulations to the wound, leading to biological and biochemical effects, with the potential to substantially influence wound-host interactions, and when properly applied may enhance wound healing. RNPT is a simple, safe, and affordable tool that can be utilized in a wide range of acute and chronic conditions, with reduced need for complicated surgical procedures, and antibiotic treatment. This technology has been shown to be effective and safe, saving limbs and lives on a global scale. Regulated, oxygen-enriched negative pressure-assisted wound therapy (RO-NPT is an innovative technology, whereby supplemental oxygen is concurrently administered with RNPT for their synergistic effect on treatment and prophylaxis of anaerobic wound infection and promotion of wound healing. Understanding the basic science, modes of operation and the associated risks of these technologies through their fundamental clinical mechanisms is the main objective of this review.

  10. International Health Regulations in practice: Focus on yellow fever and poliomyelitis.

    Science.gov (United States)

    Simons, H; Patel, D

    2016-10-02

    ASBTRACT The spread of infectious disease represents a global threat and therefore remains a priority on the international public health agenda. The International Health Regulations (IHR) (2005) came into effect in June 2007 and provide a legal framework to which the 196 member states of the World Health Assembly agree to abide. 1 These regulations include implementation of protective, control and response measures at points of entry to a country (i.e. land borders, sea and airports), and of notification measures, all of which aim to prevent or limit the spread of disease while minimising disruption to international trade. The World Health Organization can apply and enforce IHR (2005) to any disease considered to pose a significant threat to international public health. This short paper focuses on 2 diseases; yellow fever and poliomyelitis, both of which have the potential to spread internationally. It will discuss the measures applied under IHR (2005) to minimize the threat, and explore the implications for both travelers and travel health advisors.

  11. Synergistic Effect of Auto-Activation and Small RNA Regulation on Gene Expression

    Science.gov (United States)

    Xiong, Li-Ping; Ma, Yu-Qiang; Tang, Lei-Han

    2010-09-01

    Auto-activation and small ribonucleic acid (RNA)-mediated regulation are two important mechanisms in controlling gene expression. We study the synergistic effect of these two regulations on gene expression. It is found that under this combinatorial regulation, gene expression exhibits bistable behaviors at the transition regime, while each of these two regulations, if working solely, only leads to monostability. Within the stochastic framework, the base pairing strength between sRNA and mRNA plays an important role in controlling the transition time between on and off states. The noise strength of protein number in the off state approaches 1 and is smaller than that in the on state. The noise strength also depends on which parameters, the feedback strength or the synthesis rate of small RNA, are tuned in switching the gene expression on and off. Our findings may provide a new insight into gene-regulation mechanism and can be applied in synthetic biology.

  12. Synergistic Effect of Auto-Activation and Small RNA Regulation on Gene Expression

    International Nuclear Information System (INIS)

    Li-Ping, Xiong; Yu-Qiang, Ma; Lei-Han, Tang

    2010-01-01

    Auto-activation and small ribonucleic acid (RNA)-mediated regulation are two important mechanisms in controlling gene expression. We study the synergistic effect of these two regulations on gene expression. It is found that under this combinatorial regulation, gene expression exhibits bistable behaviors at the transition regime, while each of these two regulations, if working solely, only leads to monostability. Within the stochastic framework, the base pairing strength between sRNA and mRNA plays an important role in controlling the transition time between on and off states. The noise strength of protein number in the off state approaches 1 and is smaller than that in the on state. The noise strength also depends on which parameters, the feedback strength or the synthesis rate of small RNA, are tuned in switching the gene expression on and off. Our findings may provide a new insight into gene-regulation mechanism and can be applied in synthetic biology

  13. Six Reasons why hours of service regulations for truck drivers are violated

    DEFF Research Database (Denmark)

    Grøn, Sisse

    2008-01-01

      ABSTRACT Two decades of research has established a correlation between tiredness and fatigue, and traffic accident involving truck drivers.  Regulations limiting the driving hours of truck drivers thus are necessary precautions. But compliance is a problem. The answer from authorities tend to b...... independency ideal among truck drivers. The last reason is that the drivers and their employers share an interest in long work hours.......  ABSTRACT Two decades of research has established a correlation between tiredness and fatigue, and traffic accident involving truck drivers.  Regulations limiting the driving hours of truck drivers thus are necessary precautions. But compliance is a problem. The answer from authorities tend...... is that the regulation seems to be designed to long distance driving, and has some short-comings when applied to short distance drivers. The third reason is that the regulation deprives the drivers of means to control their tiredness. The fourth reason is that the regulation limits room for planning ahead generally...

  14. A macromarketing perspective on food safety regulation

    DEFF Research Database (Denmark)

    Bech-Larsen, Tino; Aschemann-Witzel, Jessica

    2012-01-01

    of the major stakeholders in the Danish food marketing system. Adding to the literature on diffusion of regulatory initiatives, the analysis shows that the Danish ban on trans-fats had—and still has—an important impact on trans-fat regulation in other European and overseas countries. In the final section......This article discusses the implementation and diffusion of mandatory and voluntary food safety regulations from a marketing systems perspective, and specifically applies this framework to an analysis of the antecedents and implications of the Danish 2003 ban on trans-fatty acids (TFAs......). The analysis is based on reviews of published material and on interviews with food marketers, nutrition experts, and policy makers. It is established that the ban was implemented due to scientific proof of health risks associated with the intake of TFAs but also as a result of aligned interests and efforts...

  15. Application of non-linear discretetime feedback regulators with assignable closed-loop dynamics

    Directory of Open Access Journals (Sweden)

    Dubljević Stevan

    2003-01-01

    Full Text Available In the present work the application of a new approach is demonstrated to a discrete-time state feedback regulator synthesis with feedback linearization and pole-placement for non-linear discrete-time systems. Under the simultaneous implementation of a non-linear coordinate transformation and a non-linear state feedback law computed through the solution of a system of non-linear functional equations, both the feedback linearization and pole-placement design objectives were accomplished. The non-linear state feedback regulator synthesis method was applied to a continuous stirred tank reactor (CSTR under non-isothermal operating conditions that exhibits steady-state multiplicity. The control objective was to regulate the reactor at the middle unstable steady state by manipulating the rate of input heat in the reactor. Simulation studies were performed to evaluate the performance of the proposed non-linear state feedback regulator, as it was shown a non-linear state feedback regulator clearly outperformed a standard linear one, especially in the presence of adverse disturbance under which linear regulation at the unstable steady state was not feasible.

  16. Adaptive compliant structures for flow regulation

    Science.gov (United States)

    Brinkmeyer, Alex; Theunissen, Raf; M. Weaver, Paul; Pirrera, Alberto

    2017-01-01

    This paper introduces conceptual design principles for a novel class of adaptive structures that provide both flow regulation and control. While of general applicability, these design principles, which revolve around the idea of using the instabilities and elastically nonlinear behaviour of post-buckled panels, are exemplified through a case study: the design of a shape-adaptive air inlet. The inlet comprises a deformable post-buckled member that changes shape depending on the pressure field applied by the surrounding fluid, thereby regulating the inlet aperture. By tailoring the stress field in the post-buckled state and the geometry of the initial, stress-free configuration, the deformable section can snap through to close or open the inlet completely. Owing to its inherent ability to change shape in response to external stimuli—i.e. the aerodynamic loads imposed by different operating conditions—the inlet does not have to rely on linkages and mechanisms for actuation, unlike conventional flow-controlling devices. PMID:28878567

  17. 20 CFR 660.300 - What definitions apply to the regulations for workforce investment systems under title I of WIA?

    Science.gov (United States)

    2010-04-01

    ..., age, sex, and disability required by 29 CFR part 37 of the DOL regulations implementing section 188 of... title I. Participation commences on the first day, following determination of eligibility, on which the... Secretary of the U.S. Department of Labor. Self certification means an individual's signed attestation that...

  18. Scientific foundation of regulating ionizing radiation: application of metrics for evaluation of regulatory science information.

    Science.gov (United States)

    Moghissi, A Alan; Gerraa, Vikrham Kumar; McBride, Dennis K; Swetnam, Michael

    2014-11-01

    This paper starts by describing the historical evolution of assessment of biologic effects of ionizing radiation leading to the linear non-threshold (LNT) system currently used to regulate exposure to ionizing radiation. The paper describes briefly the concept of Best Available Science (BAS) and Metrics for Evaluation of Scientific Claims (MESC) derived for BAS. It identifies three phases of regulatory science consisting of the initial phase, when the regulators had to develop regulations without having the needed scientific information; the exploratory phase, when relevant tools were developed; and the standard operating phase, when the tools were applied to regulations. Subsequently, an attempt is made to apply the BAS/MESC system to various stages of LNT. This paper then compares the exposure limits imposed by regulatory agencies and also compares them with naturally occurring radiation at several cities. Controversies about LNT are addressed, including judgments of the U.S. National Academies and their French counterpart. The paper concludes that, based on the BAS/MESC system, there is no disagreement between the two academies on the scientific foundation of LNT; instead, the disagreement is based on their judgment or speculation.

  19. Stabilizing in vitro ultrasound-mediated gene transfection by regulating cavitation.

    Science.gov (United States)

    Lo, Chia-Wen; Desjouy, Cyril; Chen, Shing-Ru; Lee, Jyun-Lin; Inserra, Claude; Béra, Jean-Christophe; Chen, Wen-Shiang

    2014-03-01

    It is well known that acoustic cavitation can facilitate the inward transport of genetic materials across cell membranes (sonoporation). However, partially due to the unstationary behavior of the initiation and leveling of cavitation, the sonoporation effect is usually unstable, especially in low intensity conditions. A system which is able to regulate the cavitation level during sonication by modulating the applied acoustic intensity with a feedback loop is implemented and its effect on in vitro gene transfection is tested. The regulated system provided better time stability and reproducibility of the cavitation levels than the unregulated conditions. Cultured hepatoma cells (BNL) mixed with 10 μg luciferase plasmids are exposed to 1-MHz pulsed ultrasound with or without cavitation regulation, and the gene transfection efficiency and cell viability are subsequently assessed. Experimental results show that for all exposure intensities (low, medium, and high), stable and intensity dependent, although not higher, gene expression could be achieved in the regulated cavitation system than the unregulated conditions. The cavitation regulation system provides a better control of cavitation and its bioeffect which are crucial important for clinical applications of ultrasound-mediated gene transfection. Copyright © 2013 Elsevier B.V. All rights reserved.

  20. 1990 No. 1918. The Nuclear Installations Act 1965 (Repeal and Modifications) Regulations 1990

    International Nuclear Information System (INIS)

    1990-01-01

    These Regulations entered into force on 31 October 1990. They repeal part of Section (1) of the Nuclear Installations Act 1965 to remove the exemption of the United Kingdom Atomic Energy Authority (UKAEA) from licensing under the Act. The Regulations also amend the 1965 Act to ensure that the UKAEA's duties in respect of the safety of premises it occupies will continue to apply whether or not a nuclear site licence has been granted. (NEA) [fr

  1. 40 CFR 80.574 - What labeling requirements apply to retailers and wholesale purchaser-consumers of ECA marine...

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false What labeling requirements apply to retailers and wholesale purchaser-consumers of ECA marine fuel beginning June 1, 2014? 80.574 Section 80.574 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF...

  2. Self Regulated Learning for Developing Nursing Skills via Web-Based

    Science.gov (United States)

    Razak, Rafiza Abdul; Hua, Khor Bee

    2013-01-01

    The purpose of this study is to find out whether the first year student nurses able to learn and develop the psychomotor skills for basic nursing care using web-based learning environment. More importantly, the researcher investigated whether web-based learning environment using self regulated learning strategy able to help students to apply the…

  3. Study role of different dimensions of emotional self-regulation on addiction potential.

    Directory of Open Access Journals (Sweden)

    Zahra Nikmanesh

    2014-06-01

    Full Text Available To investigate relationship between addiction potentiality and different dimensions of emotional self-regulation.This descriptive and correlational study included students of Sistan and Baluchistan University, Sistan and Baluchestan, Iran. Participants were selected by random sampling method. We applied Addiction Potential Scale (APS and Difficult in Emotion Regulation Scale (DERS for this study. For statistical analysis, Pearson correlation and regression analysis methods were used.The results show that there is a positive and significant relationship between the addiction potential and all dimensions of emotional self-regulation (excepting lack of awareness. The enter regression analysis for prediction of the APS by the DERS shows that the DERS predicts 16% of the APS variances.Regard to the results, it is necessary to introduce an especial program in emotional self-regulation for the youth with addiction potential.

  4. 76 FR 4469 - Privacy Act of 1974; Report of Modified or Altered System of Records

    Science.gov (United States)

    2011-01-25

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Privacy Act of..., HHS/CDC/NIOSH.'' HHS is proposing to add the following Breach Response Routine Use Language to comply... to the Breach of Personally Identifiable Information: To appropriate Federal agencies and Department...

  5. 76 FR 4445 - Privacy Act of 1974; Report of Modified or Altered System of Records

    Science.gov (United States)

    2011-01-25

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Privacy Act of..., ``Alien Mental Waiver Program, HHS/CDC/ NCID. HHS is proposing to add the following Breach Response..., Safeguarding Against and Responding to the Breach of Personally Identifiable Information: To appropriate...

  6. 76 FR 4451 - Privacy Act of 1974; Report of Modified or Altered System of Records

    Science.gov (United States)

    2011-01-25

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Privacy Act of..., ``Fellowship Program and Guest Researcher Records, HHS/CDC/AHRC.'' HHS is proposing to add the following Breach..., Safeguarding Against and responding to the Breach of Personally Identifiable Information: To appropriate...

  7. 76 FR 4435 - Privacy Act of 1974; Report of Modified or Altered System of Records

    Science.gov (United States)

    2011-01-25

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Privacy Act of... Interpreting Physician File, HHS/CDC/NIOSH.'' HHS is proposing to add the following Breach Response Routine Use... and responding to the Breach of Personally Identifiable Information: To appropriate Federal agencies...

  8. 76 FR 4466 - Privacy Act of 1974; Report of Modified or Altered System of Records

    Science.gov (United States)

    2011-01-25

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Privacy Act of..., HHS/CDC/NIOSH.'' HHS is proposing to add the following Breach Response Routine Use Language to comply... to the Breach of Personally Identifiable Information: To appropriate federal agencies and Department...

  9. 76 FR 4478 - Privacy Act of 1974; Report of Modified or Altered System of Records

    Science.gov (United States)

    2011-01-25

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Privacy Act of..., HHS/CDC/NCHSTP.'' HHS is proposing to add the following Breach Response Routine Use Language to comply... to the Breach of Personally Identifiable Information: To appropriate Federal agencies and Department...

  10. 77 FR 5012 - Environmental Protection Agency, Department of Health and Human Services and Department of...

    Science.gov (United States)

    2012-02-01

    ..., Department of Health and Human Services and Department of Agriculture; Memorandum of Understanding Regarding... Memorandum of Understanding (MOU). The MOU will support and encourage cooperation and communication between... Department of Human Services (HHS) and the U.S. Department of Agriculture (USDA). HHS's Centers for Disease...

  11. 78 FR 57858 - Tribal Consultation Meeting

    Science.gov (United States)

    2013-09-20

    ... and posted on the Early Childhood Learning and Knowledge Center Web site at http://eclkc.ohs.acf.hhs... DEPARTMENT OF HEALTH AND HUMAN SERVICES Administration for Children and Families Tribal Consultation Meeting AGENCY: Administration for Children and Families' Office of Head Start (OHS), HHS. ACTION...

  12. Metacognition in Self-Regulated Multimedia Learning: Integrating Behavioural, Psychophysiological and Introspective Measures

    Science.gov (United States)

    Antonietti, Alessandro; Colombo, Barbara; Di Nuzzo, Chiara

    2015-01-01

    This study aims at investigating students' strategies--as revealed by behavioural, psychophysiological and introspective measures--which are applied during the free exploration of multimedia instructional presentations, which requires students to self-regulate their learning processes. Two multimedia presentations were constructed and presented to…

  13. 75 FR 42830 - Proposed Collection; Comment Request for Regulation 112841-10

    Science.gov (United States)

    2010-07-22

    ... being made to the regulation at this time. Type of Review: Extension of a currently approved collection... hours. Estimated average annual burden hours per record-keeper: 30 minutes. Estimated number of record-keepers: 20,000. The following paragraph applies to all of the collections of information covered by this...

  14. Unusual Cases of Hypothenar Hammer Syndrome.

    Science.gov (United States)

    Orrapin, Saranat; Arworn, Supapong; Wisetborisut, Anawat

    2015-01-01

    Hypothenar hammer syndrome (HHS) is a rare occupational disease. The risk group of HHS is patient whose dominate hand used as a hammer. Our study report unusually cases in Chiang Mai University Hospital. 19 year-old basketball player had right ulnar artery aneurysm for two months. After operation, his symptom was relieved and returned to play basketball again. 65 year-old housekeeper had non-dominated hand ulnar artery aneurysm for two years. After operation she still had hand claudication due to poor run-off vessel. HHS is previously state in risk group. But from our report there was a risk in different occupation.

  15. Research needs for risk-informed, performance-based regulation

    International Nuclear Information System (INIS)

    Cloninger, T.H.

    1997-01-01

    This presentation was made by an executive in the utility which operates the South Texas Project reactors, and summarizes their perspective on probabilistic safety analysis, risk-based operation, and risk-based regulation. They view it as a tool to help them better apply their resources to maintain the level of safety necessary to protect the public health and safety. South Texas served as one of the pilot plants for the application of risk-based regulation to the maintenance rule. The author feels that the process presents opportunities as well as challenges. Among the opportunities is the involvement of more people in the process, and the sense of investment they take in the decisions, in addition to the insight they can offer. In the area of challenges there is the need for better understanding of how to apply what already is known on problems, rather than essentially reinventing the wheel to address problems. Research is needed to better understand when some events are not truly of a significant safety concern. The demarcation between deterministic decisions and the appropriate application of risk-based decisions must be better defined, for the sake of the operator as well as the public observing plant operation

  16. Applied physics

    International Nuclear Information System (INIS)

    Anon.

    1980-01-01

    The Physics Division research program that is dedicated primarily to applied research goals involves the interaction of energetic particles with solids. This applied research is carried out in conjunction with the basic research studies from which it evolved

  17. Regulation on the transport of nuclear fuel materials by vehicles

    International Nuclear Information System (INIS)

    1984-01-01

    The regulations applying to the transport of nuclear fuel materials by vehicles, mentioned in the law for the regulations of nuclear source materials, nuclear fuel materials and reactors. The transport is for outside of the factories and the site of enterprises by such modes of transport as rail, trucks, etc. Covered are the following: definitions of terms, places of fuel materials handling, loading methods, limitations on mix loading with other cargo, radiation dose rates concerning the containers and the vehicles, transport indexes, signs and indications, limitations on train linkage during transport by rail, security guards, transport of empty containers, etc. together with ordinary rail cargo and so on. (Mori, K.)

  18. Self-reported emotion regulation in adults with Tourette's syndrome.

    Science.gov (United States)

    Drury, Helena; Wilkinson, Verity; Robertson, Mary M; Channon, Shelley

    2016-11-30

    Recent work has reported mild impairments in social and emotional processing in Tourette's syndrome (TS), but deliberate attempts to use specific emotion regulation strategies have not been investigated previously. In the present study, adult participants with TS and no comorbidities (TS-alone) were compared to healthy control participants on several self-report measures assessing habitual use of reappraisal and suppression emotion regulation strategies. There were no group differences on measures of reappraisal, but the TS-alone group reported using suppression more frequently than the control group and this was true across a range of negative emotions. The groups did not differ on symptomatology scores of anxiety or depression, although more frequent use of suppression was associated with higher depressive symptomatology for the TS-alone group only. Further work is needed to examine potential factors that may influence emotion regulation in TS, including increased emotional reactivity or expertise in applying strategies to suppress tic symptoms. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  19. 78 FR 66653 - Patient Protection and Affordable Care Act; HHS Notice of Benefit and Payment Parameters for 2014...

    Science.gov (United States)

    2013-11-06

    ... Essential Health Benefits, we inadvertently included the incorrect section reference to the Affordable Care... inadvertently omitted references to paragraphs (f) and (g) of this section. On page 15540, in the regulation... 553(b) of the Administrative Procedure Act (APA) (5 U.S.C. 553(b)). However, we can waive this notice...

  20. Scaling properties reveal regulation of river flows in the Amazon through a forest reservoir

    Science.gov (United States)

    Salazar, Juan Fernando; Villegas, Juan Camilo; María Rendón, Angela; Rodríguez, Estiven; Hoyos, Isabel; Mercado-Bettín, Daniel; Poveda, Germán

    2018-03-01

    Many natural and social phenomena depend on river flow regimes that are being altered by global change. Understanding the mechanisms behind such alterations is crucial for predicting river flow regimes in a changing environment. Here we introduce a novel physical interpretation of the scaling properties of river flows and show that it leads to a parsimonious characterization of the flow regime of any river basin. This allows river basins to be classified as regulated or unregulated, and to identify a critical threshold between these states. We applied this framework to the Amazon river basin and found both states among its main tributaries. Then we introduce the forest reservoir hypothesis to describe the natural capacity of river basins to regulate river flows through land-atmosphere interactions (mainly precipitation recycling) that depend strongly on the presence of forests. A critical implication is that forest loss can force the Amazonian river basins from regulated to unregulated states. Our results provide theoretical and applied foundations for predicting hydrological impacts of global change, including the detection of early-warning signals for critical transitions in river basins.