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Sample records for hgps cases carry

  1. Antisense-Based Progerin Downregulation in HGPS-Like Patients’ Cells

    Directory of Open Access Journals (Sweden)

    Karim Harhouri

    2016-07-01

    Full Text Available Progeroid laminopathies, including Hutchinson-Gilford Progeria Syndrome (HGPS, OMIM #176670, are premature and accelerated aging diseases caused by defects in nuclear A-type Lamins. Most HGPS patients carry a de novo point mutation within exon 11 of the LMNA gene encoding A-type Lamins. This mutation activates a cryptic splice site leading to the deletion of 50 amino acids at its carboxy-terminal domain, resulting in a truncated and permanently farnesylated Prelamin A called Prelamin A Δ50 or Progerin. Some patients carry other LMNA mutations affecting exon 11 splicing and are named “HGPS-like” patients. They also produce Progerin and/or other truncated Prelamin A isoforms (Δ35 and Δ90 at the transcriptional and/or protein level. The results we present show that morpholino antisense oligonucleotides (AON prevent pathogenic LMNA splicing, markedly reducing the accumulation of Progerin and/or other truncated Prelamin A isoforms (Prelamin A Δ35, Prelamin A Δ90 in HGPS-like patients’ cells. Finally, a patient affected with Mandibuloacral Dysplasia type B (MAD-B, carrying a homozygous mutation in ZMPSTE24, encoding an enzyme involved in Prelamin A maturation, leading to accumulation of wild type farnesylated Prelamin A, was also included in this study. These results provide preclinical proof of principle for the use of a personalized antisense approach in HGPS-like and MAD-B patients, who may therefore be eligible for inclusion in a therapeutic trial based on this approach, together with classical HGPS patients.

  2. Carry

    DEFF Research Database (Denmark)

    Koijen, Ralph S.J.; Moskowitz, Tobias J.; Heje Pedersen, Lasse;

    that include global equities, global bonds, currencies, commodities, US Treasuries, credit, and equity index options. This predictability underlies the strong returns to "carry trades" that go long high-carry and short low-carry securities, applied almost exclusively to currencies, but shown here...

  3. Regional carrying capacity: case studies of Bohai Rim area

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Carrying capacity research has been carried out for a long time. However, synthesized carrying capacity researches based on systematic views began only in the 1970s. There is even less work done in China. This paper tries to address both synthesized carrying capacity research and its utilization in China. State spaces method from the systematic science was borrowed to construct the conceptual model of regional carrying capacity. Based on the conceptual model and the surveys in the Bohai Rim area, we construct a representative indicators system for quantifying regional carrying capacity in the Bohai Rim. While employing system dynamic models we simulated the evolving trend of both the regional carrying states and regional carrying capacity from 1999 to 2015. The results proved the statement that Bohai Rim is overall over-capacity for a long time and will be over-capacity in the foreseeable future. Among all the restriction factors, water shortage and environmental pollution stand out to be the two primary obstacles for Bohai Rim's sustainable development.Regional differentiation analysis further indicates that coastal areas of the Bohai Rim burden more than its overall level. However, Shandong province shows some good signs in addressing the regional carrying capacity issues. The research is successful in addressing the quantification of regional carrying capacity issues, but nonetheless it needs further refinery and more information.

  4. Pluripotent stem cells to model Hutchinson-Gilford progeria syndrome (HGPS): Current trends and future perspectives for drug discovery.

    Science.gov (United States)

    Lo Cicero, Alessandra; Nissan, Xavier

    2015-11-01

    Progeria, or Hutchinson-Gilford progeria syndrome (HGPS), is a rare, fatal genetic disease characterized by an appearance of accelerated aging in children. This syndrome is typically caused by mutations in codon 608 (p.G608G) of the LMNA, leading to the production of a mutated form of lamin A precursor called progerin. In HGPS, progerin accumulates in cells causing progressive molecular defects, including nuclear shape abnormalities, chromatin disorganization, damage to DNA and delays in cell proliferation. Here we report how, over the past five years, pluripotent stem cells have provided new insights into the study of HGPS and opened new original therapeutic perspectives to treat the disease.

  5. A High Throughput Phenotypic Screening reveals compounds that counteract premature osteogenic differentiation of HGPS iPS-derived mesenchymal stem cells

    Science.gov (United States)

    Lo Cicero, Alessandra; Jaskowiak, Anne-Laure; Egesipe, Anne-Laure; Tournois, Johana; Brinon, Benjamin; Pitrez, Patricia R.; Ferreira, Lino; de Sandre-Giovannoli, Annachiara; Levy, Nicolas; Nissan, Xavier

    2016-01-01

    Hutchinson-Gilford progeria syndrome (HGPS) is a rare fatal genetic disorder that causes systemic accelerated aging in children. Thanks to the pluripotency and self-renewal properties of induced pluripotent stem cells (iPSC), HGPS iPSC-based modeling opens up the possibility of access to different relevant cell types for pharmacological approaches. In this study, 2800 small molecules were explored using high-throughput screening, looking for compounds that could potentially reduce the alkaline phosphatase activity of HGPS mesenchymal stem cells (MSCs) committed into osteogenic differentiation. Results revealed seven compounds that normalized the osteogenic differentiation process and, among these, all-trans retinoic acid and 13-cis-retinoic acid, that also decreased progerin expression. This study highlights the potential of high-throughput drug screening using HGPS iPS-derived cells, in order to find therapeutic compounds for HGPS and, potentially, for other aging-related disorders. PMID:27739443

  6. Impact of Flexibility Options on Grid Economic Carrying Capacity of Solar and Wind: Three Case Studies

    Energy Technology Data Exchange (ETDEWEB)

    Denholm, Paul [National Renewable Energy Lab. (NREL), Golden, CO (United States); Novacheck, Joshua [National Renewable Energy Lab. (NREL), Golden, CO (United States); Jorgenson, Jennie [National Renewable Energy Lab. (NREL), Golden, CO (United States); O' Connell, Matthew [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2016-12-01

    In this study, we attempt to quantify the benefits of various options of grid flexibility by measuring their impact on two measures: economic carrying capacity and system costs. Flexibility can increase economic carrying capacity and reduce overall system costs. In some cases, options that provide a limited increase in economic carrying capacity can provide significant operational savings, thus demonstrating the need to evaluate flexibility options using multiple metrics. The value of flexibility options varies regionally due to different generation mixes and types of renewables. The more rapid decline in PV value compared to wind makes PV more dependent on adding flexibility options, including transmission and energy storage.

  7. Impact of Flexibility Options on Grid Economic Carrying Capacity of Solar and Wind: Three Case Studies

    Energy Technology Data Exchange (ETDEWEB)

    Denholm, Paul [National Renewable Energy Lab. (NREL), Golden, CO (United States); Novacheck, Joshua [National Renewable Energy Lab. (NREL), Golden, CO (United States); Jorgenson, Jennie [National Renewable Energy Lab. (NREL), Golden, CO (United States); O' Connell, Matthew [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2016-12-01

    In this study, we attempt to quantify the benefits of various options of grid flexibility by measuring their impact on two measures: economic carrying capacity and system costs. Flexibility can increase ECC and reduce overall system costs. In some cases, options that provide a limited increase in ECC can provide significant operational savings, thus demonstrating the need to evaluate flexibility options using multiple metrics. The value of flexibility options varies regionally due to different generation mixes and types of renewables. The more rapid decline in PV value compared to wind makes PV more dependent on adding flexibility options, including transmission and energy storage.

  8. Discordant gene expression signatures and related phenotypic differences in lamin A- and A/C-related Hutchinson-Gilford progeria syndrome (HGPS.

    Directory of Open Access Journals (Sweden)

    Martina Plasilova

    Full Text Available Hutchinson-Gilford progeria syndrome (HGPS is a genetic disorder displaying features reminiscent of premature senescence caused by germline mutations in the LMNA gene encoding lamin A and C, essential components of the nuclear lamina. By studying a family with homozygous LMNA mutation (K542N, we showed that HGPS can also be caused by mutations affecting both isoforms, lamin A and C. Here, we aimed to elucidate the molecular mechanisms underlying the pathogenesis in both, lamin A- (sporadic and lamin A and C-related (hereditary HGPS. For this, we performed detailed molecular studies on primary fibroblasts of hetero- and homozygous LMNA K542N mutation carriers, accompanied with clinical examinations related to the molecular findings. By assessing global gene expression we found substantial overlap in altered transcription profiles (13.7%; 90/657 in sporadic and hereditary HGPS, with 83.3% (75/90 concordant and 16.7% (15/90 discordant transcriptional changes. Among the concordant ones we observed down-regulation of TWIST2, whose inactivation in mice and humans leads to loss of subcutaneous fat and dermal appendages, and loss of expression in dermal fibroblasts and periadnexial cells from a LMNA(K542N/K542N patient further confirming its pivotal role in skin development. Among the discordant transcriptional profiles we identified two key mediators of vascular calcification and bone metabolism, ENPP1 and OPG, which offer a molecular explanation for the major phenotypic differences in vascular and bone disease in sporadic and hereditary HGPS. Finally, this study correlates reduced TWIST2 and OPG expression with increased osteocalcin levels, thereby linking altered bone remodeling to energy homeostasis in hereditary HGPS.

  9. Discordant Gene Expression Signatures and Related Phenotypic Differences in Lamin A- and A/C-Related Hutchinson-Gilford Progeria Syndrome (HGPS)

    Science.gov (United States)

    Plasilova, Martina; Chattopadhyay, Chandon; Ghosh, Apurba; Wenzel, Friedel; Demougin, Philippe; Noppen, Christoph; Schaub, Nathalie; Szinnai, Gabor; Terracciano, Luigi; Heinimann, Karl

    2011-01-01

    Hutchinson-Gilford progeria syndrome (HGPS) is a genetic disorder displaying features reminiscent of premature senescence caused by germline mutations in the LMNA gene encoding lamin A and C, essential components of the nuclear lamina. By studying a family with homozygous LMNA mutation (K542N), we showed that HGPS can also be caused by mutations affecting both isoforms, lamin A and C. Here, we aimed to elucidate the molecular mechanisms underlying the pathogenesis in both, lamin A- (sporadic) and lamin A and C-related (hereditary) HGPS. For this, we performed detailed molecular studies on primary fibroblasts of hetero- and homozygous LMNA K542N mutation carriers, accompanied with clinical examinations related to the molecular findings. By assessing global gene expression we found substantial overlap in altered transcription profiles (13.7%; 90/657) in sporadic and hereditary HGPS, with 83.3% (75/90) concordant and 16.7% (15/90) discordant transcriptional changes. Among the concordant ones we observed down-regulation of TWIST2, whose inactivation in mice and humans leads to loss of subcutaneous fat and dermal appendages, and loss of expression in dermal fibroblasts and periadnexial cells from a LMNAK542N/K542N patient further confirming its pivotal role in skin development. Among the discordant transcriptional profiles we identified two key mediators of vascular calcification and bone metabolism, ENPP1 and OPG, which offer a molecular explanation for the major phenotypic differences in vascular and bone disease in sporadic and hereditary HGPS. Finally, this study correlates reduced TWIST2 and OPG expression with increased osteocalcin levels, thereby linking altered bone remodeling to energy homeostasis in hereditary HGPS. PMID:21738662

  10. Carrying Capacity

    DEFF Research Database (Denmark)

    Schroll, Henning; Andersen, Jan; Kjærgård, Bente

    2012-01-01

    A spatial planning act was introduced inIndonesia 1992 and renewed in 2008. It emphasised the planning role of decentralised authorities. The spatial planning act covers both spatial and environmental issues. It defines the concept of carrying capacity and includes definitions of supportive...... carrying capacity (SCC) and assimilative carrying capacity (ACC). The act mandates that the latter two aspects must be taken into consideration in the local spatial plans. The present study aimed at developing a background for a national guideline for carrying capacity in Indonesian provinces and districts...... standard or governmental political objective exists. In most cases it was possible to select a set of indicators, including thresholds that are workable in a carrying capacity planning at the local administrative levels. Not all relevant sectors at the decentralized level were included. Indicators of SCC...

  11. Getting carried away: a note showing baseline observation carried forward (BOCF) results can be calculated from published complete-cases results.

    Science.gov (United States)

    Kaiser, K A; Affuso, O; Beasley, T M; Allison, D B

    2012-06-01

    Randomized controlled trials (RCTs) in obesity are plagued by missing data due to participant dropouts. Most methodologists and regulatory bodies agree that the primary analysis of such RCTs should be based on the intent-to-treat (ITT) principle, such that all randomized subjects are included in the analysis, even those who dropped out. Unfortunately, some authors do not include an ITT analysis in their published reports. Here we show that one form of ITT analysis, baseline observation carried forward (BOCF), can be performed utilizing only information available in a published complete-case (CC) analysis, permitting readers, editors, meta-analysts and regulators to easily conduct their own ITT analyses when the original authors do not report one. We mathematically derive a simple method for estimating and testing treatment effects using the BOCF to allow a more conservative comparison of treatment effects when there are dropouts in a clinical trial. We provide two examples of this method using available CC analysis data from reported obesity trials to illustrate the application for readers who wish to determine a range of treatment effects based on published summary statistics. Commonly used CC analyses may lead to inflated type I error rates and/or treatment effect estimates. The method described herein can be useful for researchers who wish to estimate a conservative range of plausible treatment effects based on limited reported data. Limitations of this method are discussed.

  12. Modelling of carrying capacity in National Park - Fruška Gora (Serbia case study

    Directory of Open Access Journals (Sweden)

    Vujko Aleksandra

    2017-03-01

    Full Text Available Negative effects of tourism development in a destination are usually the consequence of the high concentration of tourists, accommodation facilities and the activities that are practiced in a relatively restricted area. One of the most important measures to protect the areas is to calculate the maximum number of tourists that can simultaneously reside in a region, i.e. the determination of the carrying capacity. This paper outlines a method for determining carrying capacity based on zoning of environmental resources and zoning within a region. The paper argues for a return to the idea of identifying maximum appropriate number of users. The main hypothesis of the paper is based on the statement that the development of tourism in Fruška Gora (Mountain National Park in Northern Serbia must be in accordance with the basic principles of sustainability, including the determination of carrying capacity. The main research goal was to show the opinion of local residents about the uncontrolled development of tourism, and to determine the carrying capacity in four sports and recreational zones of the mountain. The carrying capacity of the area is calculated by Lavery and Stanev formulas.

  13. Modelling of carrying capacity in National Park - Fru\\vska Gora (Serbia) case study

    Science.gov (United States)

    Vujko, Aleksandra; Plavša, Jovan; Petrović, Marko D.; Radovanović, Milan; Gajić, Tamara

    2017-03-01

    Negative effects of tourism development in a destination are usually the consequence of the high concentration of tourists, accommodation facilities and the activities that are practiced in a relatively restricted area. One of the most important measures to protect the areas is to calculate the maximum number of tourists that can simultaneously reside in a region, i.e. the determination of the carrying capacity. This paper outlines a method for determining carrying capacity based on zoning of environmental resources and zoning within a region. The paper argues for a return to the idea of identifying maximum appropriate number of users. The main hypothesis of the paper is based on the statement that the development of tourism in Fru\\vska Gora (Mountain) National Park in Northern Serbia must be in accordance with the basic principles of sustainability, including the determination of carrying capacity. The main research goal was to show the opinion of local residents about the uncontrolled development of tourism, and to determine the carrying capacity in four sports and recreational zones of the mountain. The carrying capacity of the area is calculated by Lavery and Stanev formulas.

  14. Ecological carrying capacity assessment of diving site: A case study of Mabul Island, Malaysia.

    Science.gov (United States)

    Zhang, Li-Ye; Chung, Shan-Shan; Qiu, Jian-Wen

    2016-12-01

    Despite considered a non-consumptive use of the marine environment, diving-related activities can cause damages to coral reefs. It is imminent to assess the maximum numbers of divers that can be accommodated by a diving site before it is subject to irreversible deterioration. This study aimed to assess the ecological carrying capacity of a diving site in Mabul Island, Malaysia. Photo-quadrat line transect method was used in the benthic survey. The ecological carrying capacity was assessed based on the relationship between the number of divers and the proportion of diver damaged hard corals in Mabul Island. The results indicated that the proportion of diver damaged hard corals occurred exponentially with increasing use. The ecological carrying capacity of Mabul Island is 15,600-16,800 divers per diving site per year at current levels of diver education and training with a quarterly threshold of 3900-4200 per site. Our calculation shows that management intervention (e.g. limiting diving) is justified at 8-14% of hard coral damage. In addition, the use of coral reef dominated diving sites should be managed according to their sensitivity to diver damage and the depth of the reefs. Copyright © 2016 Elsevier Ltd. All rights reserved.

  15. Peculiarities of carrying capacity evaluations of cylindrical CFST columns with new type casing

    Directory of Open Access Journals (Sweden)

    Sinkovskaya Olena

    2017-01-01

    Full Text Available This paper deals with a cylindrical steel-concrete load-bearing unit. The feature of the unit is a steel mesh casing that is made from the expanded metal mesh. The optimal parameters of the suggested footing are determined taking into account anisotropy, i. e. different strength and rigidity in different directions that coincide and do not coincide with the direction of reinforcement. The optimal cell angle, when a casing deformation brings about maximum compression of a concrete core, is determined. Details for theoretical calculation of the bearing capacity of a cylindrical steel-concrete load-bearing unit are provided taking into consideration a complex three-dimensional structure of the suggested mesh casing. The validity of the calculations is confirmed by comparison them with the results of the Lira software package. The results of the calculations are provided in the form of the table showing the dependence of the adduced thickness of the plate on the longitudinal movement of the strip of the steel mesh casing. The dependencies to determine the adduced thickness of the mesh casing using the graphical method are provided for all the existing types of the mesh using concrete wedges or excluding them.

  16. Carrying Capacity

    DEFF Research Database (Denmark)

    Schroll, Henning; Andersen, Jan; Kjærgård, Bente

    2012-01-01

    A spatial planning act was introduced inIndonesia 1992 and renewed in 2008. It emphasised the planning role of decentralised authorities. The spatial planning act covers both spatial and environmental issues. It defines the concept of carrying capacity and includes definitions of supportive...... and ACC may increase the political focus on resources and environmental issues and may help to move local authorities towards a more holistic spatial planning approach. A carrying capacity approach could be an inspiration for local spatial planning in developing countries. A spatial planning act...... was introduced inIndonesia 1992 and renewed in 2008. It emphasised the planning role of decentralised authorities. The spatial planning act covers both spatial and environmental issues. It defines the concept of carrying capacity and includes definitions of supportive carrying capacity (SCC) and assimilative...

  17. Do really all wolf spiders carry spiderlings on their opisthosomas? The case of Hygrolycosa rubrofasciata (Araneae: Lycosidae

    Directory of Open Access Journals (Sweden)

    Dolejš, Petr

    2013-06-01

    Full Text Available Wolf spider females are characterised by carrying cocoons attached to their spinnerets. Emerged spiderlings are carried on the females’ opisthosomas, with the exception of three Japanese lycosid species who carry spiderlings on empty cocoons. Here, the same behaviour is recorded in a European spider: the drumming wolf spider Hygrolycosa rubrofasciata. Spiderlings of this species do not try to climb on the female’s opisthosoma, even when they are adopted by a female of a species with a normal pulli-carrying behaviour. This behaviour occurs in Trechaleidae and four unrelated species of Lycosidae inhabiting wet habitats and is therefore regarded as an adaptation to the unsuitable environment.

  18. Case Report: Analytical Electron Microscopy of Lung Granulomas Associated with Exposure to Coating Materials Carried by Glass Wool Fibers

    Science.gov (United States)

    Ferreira, Angela S.; Moreira, Valéria B.; Castro, Marcos César S.; Soares, Porfírio J.; Algranti, Eduardo; Andrade, Leonardo R.

    2010-01-01

    Context Man-made vitreous fibers (MMVFs) are noncrystalline inorganic fibrous material used for thermal and acoustical insulation (e.g., rock wool, glass wool, glass microfibers, and refractory ceramic fibers). Neither epidemiologic studies of human exposure nor animal studies have shown a noticeable hazardous effect of glass wools on health. However, MMVFs have been anecdotally associated with granulomatous lung disease in several case reports. Case presentation Here, we describe the case of a patient with multiple bilateral nodular opacities who was exposed to glass wool fibers and coating materials for 7 years. Bronchoalveolar lavage fluid revealed an increased total cell count (predominantly macrophages) with numerous cytoplasmic particles. Lung biopsy showed peribronchiolar infiltration of lymphoid cells and many foreign-body–type granulomas. Alveolar macrophages had numerous round and elongated platelike particles inside the cytoplasm. X-ray microanalysis of these particles detected mainly oxygen/aluminum/silicon and oxygen/magnesium/silicon, compatible with kaolinite and talc, respectively. No elemental evidence for glass fibers was found in lung biopsy. Discussion The contribution of analytical electron microscopy applied in the lung biopsy was imperative to confirm the diagnosis of pneumoconiosis associated with a complex occupational exposure that included both MMVFs and coating materials. Relevance to clinical or professional practice This case study points out the possible participation of other components (coating materials), beyond MMVFs, in the etiology of pneumoconiosis. PMID:20123612

  19. An explicit solution for the dynamics of a taut string of finite length carrying a traveling mass: the subsonic case

    Science.gov (United States)

    Maria Bersani, Alberto; Della Corte, Alessandro; Piccardo, Giuseppe; Rizzi, Nicola Luigi

    2016-08-01

    The authors investigate the linear vibrations induced in an elastic string by a loading point-like mass constrained to moving on it with constant horizontal velocity. Exact solutions are shown in the case of subsonic regime. The displacement is explicitly provided in terms of a power series determined by iteration, which is shown to converge to the solution of the problem. The presence of a discontinuity in the right extremum of the considered space interval is also shown both analytically and numerically.

  20. A case of primary selective hypoaldosteronism carrying three mutations in the aldosterone synthase (Cyp11b2) gene.

    Science.gov (United States)

    Taranta, Anna; Bizzarri, Carla; Masotti, Andrea; Sciré, Giuseppe; Pampanini, Valentina; Cappa, Marco

    2012-05-25

    An infant with a clinical phenotype of early onset hypoaldosteronism has been screened for mutation analysis of the Cyp11b2 gene encoding aldosterone synthase enzyme. We have described a novel nonsense mutation in exon 3 (c.508C>T) that gave rise to a shorter protein (Q170X) and two known concurrent missense mutations (c.594A>C in exon 3 and c.1157T>C in exon 7) that led to substitution of glutamic acid for aspartic acid at amino acid position 198 (E198D) and of valine for alanine at amino acid position 386 (V386A). The father, who carried E198D plus V386A mutations, showed a fractional sodium excretion of 1.25% that was unmodified by dietary salt restriction, suggesting a mild haploinsufficiency. We examined by in silico analysis the effect of the mutations on the secondary and tertiary structures of aldosterone synthase to explain the inefficient enzymatic activity. The Q170X mutation produced a truncated protein, which was consequently associated with a loss of catalytic activity. As predicted by JPred web system and Dock 6.3 software, the concurrent expression of E198D and V386A mutations induced a significant secondary structure rearrangement and a shift of the heme group and the 18-hydroxycorticosterone substrate from their optimal placement.

  1. Cytogenetic, molecular and testicular tissue studies in an infertile 45,X male carrying an unbalanced (Y;22) translocation: case report.

    Science.gov (United States)

    Brisset, S; Izard, V; Misrahi, M; Aboura, A; Madoux, S; Ferlicot, S; Schoevaert, D; Soufir, J C; Frydman, R; Tachdjian, G

    2005-08-01

    (Y;autosome) translocations have been reported in association with male infertility. Different mechanisms have been suggested to explain the male infertility, such as deletion of the azoospermic factor (AZF) on the long arm of the Y chromosome, or meiosis impairment. We describe a new case with a de novo unbalanced translocation t(Y;22) and discuss the genotype-phenotype correlation. A 36 year old male with azoospermia was found to have a mosaic 45,X/46,X, + mar karyotype. Fluorescence in situ hybridization (FISH) showed the presence of a derivative Y chromosome containing the short arm, the centromere and a small proximal part of the long-arm euchromatin of the Y chromosome and the long arm of chromosome 22. The unstable small marker chromosome included the short arm and the centromere of chromosome 22. This unbalanced translocation t(Y;22)(q11.2;q11.1) generated the loss of the long arm of the Y chromosome involving a large part of AZFb, AZFc and Yq heterochromatin regions. Testicular tissue analyses showed sperm in the wet preparation. Our case shows the importance of documenting (Y;autosome) translocations with molecular and testicular tissue analyses.

  2. Effective carrying capacity and analytical solution of a particular case of the Richards-like two-species population dynamics model

    Science.gov (United States)

    Cabella, Brenno Caetano Troca; Ribeiro, Fabiano; Martinez, Alexandre Souto

    2012-02-01

    We consider a generalized two-species population dynamic model and analytically solve it for the amensalism and commensalism ecological interactions. These two-species models can be simplified to a one-species model with a time dependent extrinsic growth factor. With a one-species model with an effective carrying capacity one is able to retrieve the steady state solutions of the previous one-species model. The equivalence obtained between the effective carrying capacity and the extrinsic growth factor is complete only for a particular case, the Gompertz model. Here we unveil important aspects of sigmoid growth curves, which are relevant to growth processes and population dynamics.

  3. Carrying capacity and tourism planning. case study at Praia Brava- Itajai, in face to the settlement of Canto da Brava Resort

    Directory of Open Access Journals (Sweden)

    Doris Van de Meene Ruschmann

    2008-05-01

    Full Text Available Sustainable tourism presumes cultural authenticity, social inclusion, conservation of natural resources and service quality. Those are major issues standing for economical viability in the long run. This article analyzes carrying capacity in Praia Brava, Itajai/SC, evaluating environmental comfort for dwellers as well as for users of the beach building future scenarios as Canto da Brava resort is settled. Tourism carrying capacity is tied to methods of identification and evaluation of environmental indicators. In this case, Cifuentes Method was chosen because it integrates physical, biotical and infra structural factors, through assessment of physical, real and effective carrying capacity. Quantitative results have been considered analyzing impacts and tolerable limits of change taking into account users perception.

  4. Study of Three Cases of Hutchinson - Gilford Progeria Syndrome in A Guangxi Han Family:Analysis of Mitochondrial DNA D-loop Region Mutations%广西汉族早老症家系三例病例研究--线粒体 DNAD -环区突变分析

    Institute of Scientific and Technical Information of China (English)

    李福记; 方玲; 胡启平; 袁志刚; 舒伟; 吴华裕; 韩焕钦; 陈凤平; 覃霞; 吕宇; 林有坤; 舒艳; 张伟峰

    2015-01-01

    目的:探讨广西汉族1个早老症家系中3例儿童早老症(HGPS)患者线粒体 DNA D -环区(D - loop区)突变是否呈现年龄相关的突变累积。方法采用聚合酶链反应(PCR)对3例 HGPS 患者及其父母、8例正常老人(正常老人组)的线粒体 DNA D - loop 区进行扩增、测序。结果正常老年人线粒体 DNA D - loop 区较 Cambridge 序列存在较多的突变位点,HGPS 患者与正常老人组线粒体 DNA D - loop 区突变率差异具有统计学意义( P ﹤0.05);3例HGPS 患者线粒体 DNA D - loop 区单体型与其母亲一致;未检测到3例 HGPS 患者线粒体 DNA D - loop 区发生新突变,也未检测到3例 HGPS 患者线粒体 DNA D - loop 区存在差异。结论该家系3例 HGPS 患者在7岁前未发生线粒体DNA D - loop 突变累积,且不同年龄患者均未见年龄相关的突变累积,推论线粒体 DNA 突变不是该家系 HGPS 患者加速衰老的重要原因。%Objective To investigate whether age - related mutation accumulation occurs in the mitochondrial DNA (mtDNA)D - loop region of three cases with Hutchinson - Gilford progeria syndrome( HGPS)in a Guangxi Han family. Methods Polymerase chain reaction(PCR)was used to amplify the mtDNA D - loop region of the three HGPS cases and their parents,as well as 8 normal seniors,and all the PCR products were sequenced and analyzed. Results The normal elders had more mutation sites in the mtDNA D - loop region compared with Cambridge standard sequence,and the three HGPS cases and the normal elders were significantly different in the mutation in the mtDNA D - loop region(P ﹤ 0. 05);the three HGPS cases had same haplotype with their mothers;no new mutations were noted in the mtDNA D - loop region of the three HGPS cases,and no differences were observed in the mtDNA D - loop region among the three HGPS cases. Conclusion No mutation accumulation was observed in the mtDNA D - loop region of the three HGPS cases

  5. Systemic vascular phenotypes of Loeys-Dietz syndrome in a child carrying a de novo R381P mutation in TGFBR2: a case report

    OpenAIRE

    Uike, Kiyoshi; Matsushita, Yuki; Sakai, Yasunari; Togao, Osamu; Nagao, Michinobu; Ishizaki, Yoshito; Nagata, Hazumu; Yamamura, Kenichiro; Torisu, Hiroyuki; Hara, Toshiro

    2013-01-01

    Background Loeys–Dietz syndrome, also known as Marfan syndrome type II, is a rare connective tissue disorder caused by dominant mutations in transforming growth factor-beta receptors (TGFBR1 and 2). Case presentation We report a 7-year-old Japanese boy with Loeys–Dietz syndrome who carried a novel, de novo missense mutation in TGFBR2 (c.1142g > c, R381P). He showed dysmorphic faces and skeletal malformations that were typical in previous cases with Loeys-Dietz syndrome. The cardiac studies di...

  6. Systemic vascular phenotypes of Loeys-Dietz syndrome in a child carrying a de novo R381P mutation in TGFBR2: a case report

    OpenAIRE

    Uike, Kiyoshi; MATSUSHITA, YUKI; Sakai, Yasunari; Togao, Osamu; Nagao, Michinobu; Ishizaki, Yoshito; Nagata, Hazumu; Yamamura, Kenichiro; Torisu, Hiroyuki; Hara, Toshiro

    2013-01-01

    Background Loeys–Dietz syndrome, also known as Marfan syndrome type II, is a rare connective tissue disorder caused by dominant mutations in transforming growth factor-beta receptors (TGFBR1 and 2). Case presentation We report a 7-year-old Japanese boy with Loeys–Dietz syndrome who carried a novel, de novo missense mutation in TGFBR2 (c.1142g > c, R381P). He showed dysmorphic faces and skeletal malformations that were typical in previous cases with Loeys-Dietz syndrome. The cardiac studies di...

  7. The Pathogenic Mechanisms and Therapeutic Strategies of Hutchinson-Gilford Progeria Syndrome%早老症(HGPS)的发病机制与治疗策略

    Institute of Scientific and Technical Information of China (English)

    曾涛; 刘新光; 周中军

    2007-01-01

    早老症(Hutchinson-Gilford Progeria Syndrome,HGPS)是一种早发而严重的过早老化性疾病.它是由于编码A/C型核纤层蛋白的LMNA基因发生点突变而引起.这个突变激活了基因11号外显子上一个隐蔽的剪接位点,产生了一种被截短了50个氨基酸的A型核纤层蛋白.然而,一个广泛分布于核膜上结构蛋白的突变,如何引起HGPS患者的早老表现,目前还不太清楚.最近研究发现,HGPS患者的细胞核结构与功能发生了各种异常,主要表现在:progerin蓄积与核变形、细胞核机械性质的改变、组蛋白修饰方式与外遗传控制的改变、基因表达调控异常、p53信号传导通路激活和基因组不稳定等方面.目前存在机械应激假说和基因表达失控假说两种假说解释HGPS的发病机制.对于HGPS患者,尚无有效的临床干预措施,但有学者提出了一些治疗策略,如应用法尼基化的抑制剂、反义寡核苷酸和RNA干扰方法.HGPS被认为是研究正常衰老机制的一个模型.对HGPS深入研究将有助于阐明A型核纤层蛋白和核膜的正常生理功能,及其在生理衰老和疾病中的作用.

  8. Clinical and radiographic features of Hutchinson-Gilford progeria syndrome: A case report.

    Science.gov (United States)

    Alves, Daniel Berretta; Silva, Juliana Melo; Menezes, Tatiany Oliveira; Cavaleiro, Rosely Santos; Tuji, Fabrício Mesquita; Lopes, Marcio Ajudarte; Zaia, Alexandre Augusto; Coletta, Ricardo Della

    2014-03-16

    Hutchinson-Gilford progeria syndrome (HGPS) is a rare dysmorphic syndrome characterized by several features of premature aging with clinical involvement of the skin, bones, and cardiovascular system. HGPS has an estimated incidence of one in four million to one in eight million births. The main clinical features of HGPS include short stature, craniofacial dimorphism, alopecia, bone fragility, and cardiovascular disorders. The most frequent cause of death is myocardial infarction at a mean age of 13 years old. Dental manifestations include delayed development and eruption of teeth, discoloration, crowding and rotation of teeth, and displaced teeth. Cone beam computed tomography images revealed the absence of the sphenoid, frontal, and maxillary sinus, flattening of the condyles and glenoid fossa, and bilateral hypoplasia of the mandibular condyles. The disease is caused by mutations in lamin A/C (LMNA). Here, we present a case report of an 11-year-old boy with classical features of HGPS, which was caused by a de novo germ-line mutation (C1824T, G608G) in exon 11 of the LMNA gene. Some uncommon HGPS-associated features in our patient, such as alterations in the facial sinuses and hypoplasia of the condyles, contributed to the expansion of the phenotypic spectrum of this syndrome from a dentomaxillofacial perspective.

  9. A case of familial transmission of community-acquired methicillin-resistant Staphylococcus aureus carrying the Inu(A) gene in Santa Fe city, Argentina.

    Science.gov (United States)

    Méndez, Emilce de Los A; Roldán, María L; Baroni, María R; Mendosa, María A; Cristóbal, Sabrina A; Virgolini, Stella M; Faccone, Diego

    2012-01-01

    Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) is increasingly recognized as an important pathogen causing skin and soft tissue infections as well as necrotizing pneumonia. We describe a case of familial transmission of CA-MRSA between a 6-month-old boy and his mother in Santa Fe City, Argentina. Both isolates showed an identical antimicrobial susceptibility profile, carried type IV SCCmec and harboured the pvl and the lnu(A) genes. Isolates showed indistinguishable SmaI-PFGE patterns confirming their genetic relationship. These results corroborate the intrafamilial transmission of CA-MRSA and might associate this strain with the repetitive events of furunculosis within the family.

  10. Emergy measures of carrying capacity and sustainability of a target region for an ecological restoration programme: a case study in Loess Hilly Region, China.

    Science.gov (United States)

    Dang, Xiaohu; Liu, Guobin

    2012-07-15

    Evaluating the sustainability of a target region for an ecological restoration programme is challenging because it involves different aspects of human society and environment as well as multiple disciplines. Carrying capacity provides a useful measure of the sustainability of a given region where an ecological restoration programme is implemented. In this article, the Yangou catchment, a geomorphic unit, was used as a case study in the Loess Hilly Region of China, where emergy synthesis was used to measure the environmental resources base. The specific standard of living in terms of emergy was employed to calculate carrying capacity over the period 1998-2005 and to assess the sustainability of the Yangou catchment where an ecological restoration programme was carried out. The results of the evaluation indicated that after implementing the ecological restoration programme, there was some improvement in the environmental aspects of the Yangou catchment during the study period, suggesting that the ecological restoration programme alleviated ecological degradation. However, several emergy-based indices and the support areas also illustrated that the ecological restoration programme was not successful enough in terms of preservation and utilisation of environmental resources to enhance sustainability. This indicates that further actions are necessary on conserving environmental resources, improving the emergy input structure for agricultural production and in lifestyle changes for the local people in living in the Yangou catchment.

  11. Water ecological carrying capacity of urban lakes in the context of rapid urbanization: A case study of East Lake in Wuhan

    Science.gov (United States)

    Ding, Lei; Chen, Kun-lun; Cheng, Sheng-gao; Wang, Xu

    With the excessive development of social economy, water scarcity and water environment deterioration become a common phenomenon in metropolis. As a crucial component of urban water environment system, urban lake is mainly influenced by social economic system and tourism system. In this paper, a framework for quantitatively evaluating development sustainability of urban lake was established by a multi-objective model that represented water ecological carrying capacity (WECC). And nine key indicators including population, irrigation area, tourist quantity, the average number of hotel daily reception, TP, TN, CODMn, BOD5 were chosen from urban social-economy system and natural resilience aspects, with their index weight was determined by using the Structure Entropy Weight method. Then, we took Wuhan East Lake, the largest urban lake in China as a case study, and selected five time sections including 2002, 2004, 2007, 2009 and 2012 to synthetically evaluate and comparatively analyze the dynamic change of WECC. The results showed that: firstly, the water ecological carrying capacity values of the East Lake in five time sections were 1.17, 1.07, 1.64, 1.53 and 2.01 respectively, which all exceeded 1 and increased fluctuation. The rapid growth of population and GDP lead to sharply increasing demand for water quantity. However, a large amount of the domestic sewage and industrial waste led by economic development increases pressure on ecological environment of urban lakes. Secondly, the carrying capacity of the East Lake for tourist activities was still low. The value in 2012 was only 0.22, keeping at a slowly increasing phase, which indicates that the East Lake has large opportunity and space for developing the water resource carrying capacity and could make further efforts to attract tourists. Moreover, the WECC of the East Lake was mainly affected by rapid social and economic development and water environment damage caused by organic pollutants. From the view of urban

  12. Lobular neoplasia detected in MRI-guided core biopsy carries a high risk for upgrade: a study of 63 cases from four different institutions.

    Science.gov (United States)

    Khoury, Thaer; Kumar, Prasanna R; Li, Zaibo; Karabakhtsian, Rouzan G; Sanati, Souzan; Chen, Xiwei; Wang, Dan; Liu, Song; Reig, Beatriu

    2016-01-01

    There are certain criteria to recommend surgical excision for lobular neoplasia diagnosed in mammographically detected core biopsy. The aims of this study are to explore the rate of upgrade of lobular neoplasia detected in magnetic resonance imaging (MRI)-guided biopsy and to investigate the clinicopathological and radiological features that could predict upgrade. We reviewed 1655 MRI-guided core biopsies yielding 63 (4%) cases of lobular neoplasia. Key clinical features were recorded. MRI findings including mass vs non-mass enhancement and the reason for biopsy were also recorded. An upgrade was defined as the presence of invasive carcinoma or ductal carcinoma in situ in subsequent surgical excision. The overall rate of lobular neoplasia in MRI-guided core biopsy ranged from 2 to 7%, with an average of 4%. A total of 15 (24%) cases had an upgrade, including 5 cases of invasive carcinoma and 10 cases of ductal carcinoma in situ. Pure lobular neoplasia was identified in 34 cases, 11 (32%) of which had upgrade. In this group, an ipsilateral concurrent or past history of breast cancer was found to be associated with a higher risk of upgrade (6/11, 55%) than contralateral breast cancer (1 of 12, 8%; P=0.03). To our knowledge, this is the largest series of lobular neoplasia diagnosed in MRI-guided core biopsy. The incidence of lobular neoplasia is relatively low. Lobular neoplasia detected in MRI-guided biopsy carries a high risk for upgrade warranting surgical excision. However, more cases from different types of institutions are needed to verify our results.

  13. Quantitative Evaluation of Sustainable Development and Eco-Environmental Carrying Capacity in Water-Deficient Regions:A Case Study in the Haihe River Basin, China

    Institute of Scientific and Technical Information of China (English)

    WANG Zhong-gen; LUO Yu-zhou; ZHANG Ming-hua; XIA Jun

    2014-01-01

    Quantitative assessment of development sustainability could be a challenge to regional management and planning, especially for areas facing great risks of water shortage. Surface-water decline and groundwater over-pumping have caused serious environmental problems and limited economic development in many regions all around the world. In this paper, a framework for quantitatively evaluating development sustainability was established with water-related eco-environmental carrying capacity (EECC) as the core measure. As a case study, the developed approach was applied to data of the Haihe River Basin, China, during 1998 through 2007. The overall sustainable development degree (SDD) is determined to be 0.39, suggesting that this rate of development is not sustainable. Results of scenario analysis revealed that overshoot, or resource over-exploitation, of the Basin’s EECC is about 20% for both population and economy. Based on conditions in the study area in 2007, in order to achieve sustainable development, i.e., SDD>0.70 in this study, the EECC could support a population of 108 million and gross domestic product (GDP) of 2.72 trillion CNY. The newly developed approach in quantifying eco-environmental carrying capacity is anticipated to facilitate sustainable development oriented resource management in water-deifcient areas.

  14. Problem in application carrying capacity approach for land allocation assessment in Indonesian municipal spatial planning: A case of Kutai Kartanegara Regency

    Science.gov (United States)

    Wijaya, I. N. S.; Rahadi, B.; Lusiana, N.; Maulidina, I.

    2017-06-01

    Urbanization in many countries, such as Indonesia, is commonly appeared as a dynamic population of developed areas. It is followed with reducing rural uses of land for improving urban land uses such as housing, industry, infrastructure, etc. in response to the growth of population. One may not be sufficiently considered by the urban planners and the decision makers, urbanization also means escalation of natural resources consumption that should be supported by the natural capacity of the area. In this situation, balancing approach as carrying capacity calculation in spatial planning is needed for sustainability. Indonesian Spatial Planning Law 26/2007 has already expressed about the balance approach in the system. Moreover, it strictly regulates the assessment and the permission system in controlling land development, especially for the conversion. However, the reductions over the rural uses of land, especially agriculture, are continuously occurred. Concerning the planning approach, this paper aims to disclose common insufficiency of carrying capacity considerations in Indonesian spatial planning practice. This paper describes common calculation weaknesses in projecting area for the urban development by recalculating the actual gap between supply and demand of agriculture land areas. Here, municipal spatial plan of Kutai Kartanegara Regency is utilized as single sample case to discuss. As the result, the recalculation shows that: 1) there are serious deficit status of agriculture land areas in order to fulfil the demanded agriculture production for the existed population, 2) some calculation of agriculture production may be miss-interpreted because of insufficient explanation toward the productivity of each agriculture commodity.

  15. Systemic vascular phenotypes of Loeys-Dietz syndrome in a child carrying a de novo R381P mutation in TGFBR2: a case report.

    Science.gov (United States)

    Uike, Kiyoshi; Matsushita, Yuki; Sakai, Yasunari; Togao, Osamu; Nagao, Michinobu; Ishizaki, Yoshito; Nagata, Hazumu; Yamamura, Kenichiro; Torisu, Hiroyuki; Hara, Toshiro

    2013-11-12

    Loeys-Dietz syndrome, also known as Marfan syndrome type II, is a rare connective tissue disorder caused by dominant mutations in transforming growth factor-beta receptors (TGFBR1 and 2). We report a 7-year-old Japanese boy with Loeys-Dietz syndrome who carried a novel, de novo missense mutation in TGFBR2 (c.1142g > c, R381P). He showed dysmorphic faces and skeletal malformations that were typical in previous cases with Loeys-Dietz syndrome. The cardiac studies disclosed the presence of markedly dilated aortic root and patent ductus aorteriosus. The cranial magnetic resonance imaging (MRI) and angiography (MRA) detected the tortuous appearances of the bilateral middle cerebral and carotid arteries. This study depicts the systemic vascular phenotypes of a child with Loeys-Dietz syndrome that were caused by a novel heterozygous mutation of TGFR2. A large cohort with serial imaging studies for vascular phenotypes will be useful for delineating the genotype-phenotype correlations of Loeys-Dietz syndrome.

  16. Correlations of the instantaneous carrying force and pressure distribution in the case of the narrow sliding radial bearing under hard shocks

    Science.gov (United States)

    Alexandrescu, I. M.; Coteţiu, R.; Darabă, D.

    2017-02-01

    We present the determining relationship of carriage in non-dimensional form for narrow radial bearings subjected to shocks and vibrations, as well as the determining relationships of the lubricant minimum thickness in relation to the dynamic loading. Due to the very short time of loading radial bearings subjected to shocks and vibrations, of about 0.5-1 ms, we consider only the approaching motion between spindle/axle and bushing on the direction of the centre line, without the rotation of the spindle/axle (the case of the non-rotating bearing), so that the effect of the lubricant expulsion be prevalent in the achieving of the self-carrying film. The paper is focused on determining relationship of carriage in dimensional form for narrow radial bearings exposed to shocks and vibrations, as well as the determining relationships of the pressure distribution from the film to be lubricated in various places of the bearing’s body. It is showed the details during the measuring accomplishments and the experimental results are registered in a record of obtained results. This paper was accepted for publication in Proceedings after double peer reviewing process but was not presented at the Conference ROTRIB’16

  17. An integrated approach for assessing aquatic ecological carrying capacity: a case study of Wujin District in the Tai Lake Basin, China.

    Science.gov (United States)

    Zeng, Chen; Liu, Yaolin; Liu, Yanfang; Hu, Jiameng; Bai, Xiaogang; Yang, Xiaoyu

    2011-01-01

    Aquatic ecological carrying capacity is an effective method for analyzing sustainable development in regional water management. In this paper, an integrated approach is employed for assessing the aquatic ecological carrying capacity of Wujin District in the Tai Lake Basin, China. An indicator system is established considering social and economic development as well as ecological resilience perspectives. While calculating the ecological index, the normalized difference vegetation index (NDVI) is extracted from Moderate Resolution Imaging Spectroradiometer (MODIS) time-series images, followed by spatial and temporal analysis of vegetation cover. Finally, multi-index assessment of aquatic ecological carrying capacity is carried out for the period 2000 to 2008, including both static and dynamic variables. The results reveal that aquatic ecological carrying capacity presents a slight upward trend in the past decade and the intensity of human activities still exceeded the aquatic ecological carrying capacity in 2008. In terms of human activities, population has decreased, GDP has quadrupled, and fertilizer application and industrial wastewater discharge have declined greatly in the past decade. The indicators representing aquatic ecosystem conditions have the lowest scores, which are primarily attributed to the water eutrophication problem. Yet the terrestrial ecosystem is assessed to be in better condition since topographic backgrounds and landscape diversity are at higher levels. Based on the work carried out, it is suggested that pollutant emission be controlled to improve water quality and agricultural development around Ge Lake (the largest lake in Wujin District) be reduced.

  18. Carrying capacity and tourism planning. case study at Praia Brava- Itajai, in face to the settlement of Canto da Brava Resort

    OpenAIRE

    Doris Van de Meene Ruschmann; Luciana Paolucci; Nelson Antonio Leite Maciel

    2008-01-01

    Sustainable tourism presumes cultural authenticity, social inclusion, conservation of natural resources and service quality. Those are major issues standing for economical viability in the long run. This article analyzes carrying capacity in Praia Brava, Itajai/SC, evaluating environmental comfort for dwellers as well as for users of the beach building future scenarios as Canto da Brava resort is settled. Tourism carrying capacity is tied to methods of identification and evaluation of environ...

  19. Analysis of Sister Carrie

    Institute of Scientific and Technical Information of China (English)

    孙淑珍

    2004-01-01

    Chapter Ⅰ Introduction  Sitting in the rocking chair,Carrie dreams her future.This is the deep impression the novel"Sister Carrie"gives us,which is written by Theodore Dreiser(1871-1945),the great American realism writer.  ……

  20. A model to assess fundamental and realized carrying capacities of island ecosystem: A case study in the southern Miaodao Archipelago of China

    Institute of Scientific and Technical Information of China (English)

    SHI Honghua; SHEN Chengcheng; ZHENG Wei; LI Fen; WANG Xiaoli; CHI Yuan; GUO Zhen

    2016-01-01

    Research on carrying capacity, aiming at maintaining the limited ability of the Earth's life supporting system to sustain human development, requires a comprehensive and ecosystem-based approach to monitor and assess the localized sustainability of coupled social and ecological systems. A definition termed the ecosystem-based carrying capacity of island (EBCCI) was developed in this paper of which the indices of fundamental and realized carrying capacities of island (FCCI and RCCI) were highlighted to emphasize the inter-dependencies between social systems and ecological systems. In order to avoid the difficulties and uncertainties of direct assessment, the related assessment model was established on the basis of synthetic evaluation of inherent and external factors affecting the EBCCI. The southern Miaodao Archipelago (SMA) located in the intersection of the Bohai Sea and the Yellow Sea, China, was taken as a typical example to acquire integrated recognition of the island ecosystem and its carrying capacity so as to discuss its sustainable development. The index scores of FCCI and RCCI in the SMA were 0.818 5 and 0.712 9 out of 1.0, respectively, with acceptable uncertainties. The results showed a relatively well capacity to sustain progress and relatively well realization of the carrying capacity of island ecosystem, owing to a well capacity of ecologically regulating, general performance of both ecologically supporting and resource provisioning, and a relatively high level of social supporting system. The study implied that it was critical to optimize the inter-dependencies and to sustain the relative balance between social systems and ecological systems so as to improve the RCCI and further facilitate the sustainability of SMA. The approach proposed in this paper provides a powerful tool which is well applicative to the regional level of an oceanic island or archipelago to study the sustainable development and can be further popularized to the coastal zone.

  1. Tourism monitoring system based on the concept of carrying capacity The case of the regional natural park Pfyn-Finges (Switzerland)

    OpenAIRE

    Michelet, Jacques Félix; Clivaz, Christophe; Hausser, Yves

    2004-01-01

    The creation of regional natural parks offers the possibility of improving the economic situation of peripheral regions. However, the use of ecologically sensitive zones for tourism also presents economic, environmental and social problems. The concept of carrying capacity is often presented as a useful approach for determining the intensity of tourism development that can be supported by a region. Our objective thus consisted in the operationalisation of this concept by defining a certain nu...

  2. Dynamic Changes of Land Ecological Carrying Capacity Based on the Ecological Footprint——By the Case Study of Chengdu City

    Institute of Scientific and Technical Information of China (English)

    Wenfu PENG; Xiaolan ZHONG; Qiuyang LI; Qin LI

    2012-01-01

    Chengdu City is in the period of rapid urbanization and industrialization, and the disturbance derived from human activities on environment is increasing remarkablely in recent 20 years. The pressure on environment, economy and population is also increasing and land use in Chengdu has changed enormously. As struc- ture and function of land ecological system change obviously, sustainable development of land productivity has been an important goal and strategic task from now on, and it is necessary to systematically research land ecological carrying capacity based on ecological footprint. The ecological footprint of Chengdu City in the past ten years was calculated and analyzed from the spatial and temporal aspects according to statistical data from 1998 to 2008, as per ecological footprint method, ecological carrying capacity and the GIS spatial analysis method, and regression analysis method. The ecological footprint and ecological carrying capacity values from 2009 to 2019 in Chengdu City were predicted through calculation results in the past ten years. The results show that the ecological footprint and ecological deficit of land use from 1998 to 2008 increased in Chengdu City. The ecological deficit of land use within the city center was in high levels in the past ten years, and the ecological footprint kept raising, especially in areas, such as Shuangliu, Chongzhou, Qingyang among 9 city areas, 4 counties and 6 districts in Chengdu City. There is fanlike distribution of ecological deficit of land use. Analysis shows that the social and natural ecological system is uneven distribution, which is not in sustainable de- velopment situation. The results of the study show that the economic, social and natural ecological system in Chengdu City is not sustainable, and the ecological foot- print is uneven distribution. The analysis of the dynamic change of land ecological carrying capacity in Chengdu City is very important for city government in the pro- cess of the

  3. Association of progerin-interactive partner proteins with lamina proteins:Mel18 is associated with emerin in HGPS%Progerin作用的伴侣蛋白和核纤层蛋白问的相互作用:在早老症中Mel18与emerin的相互作用

    Institute of Scientific and Technical Information of China (English)

    Wei-na JU; W. Ted BROWN; Nanbert ZHONG

    2009-01-01

    Objective :The Hutchinson-Gilford progeria syndrome (HGPS or progeria) is a childhood disorder with features of premature aging and is caused by mutations in the lamin A gene resulting in the production of an abnormal protein, termed progerin. To investigate the underlying pathogenic mecha-nism, we studied the nuclear co-localization and association of progerin interactive partner proteins (PIPPs) with lamina proteins. Methods:Both wild-type (WT) and progeria fibroblasts were studied by various methods including eonfocal microscopy, immunopreeipitation and Western blot. Results:All PIPPs discovered so-far co-localized with lamin A/C. In addition, the PIPPs were selectively associated with lamina proteins. An increased immunofluorescent staining signal was found for Mel18 in HGPS as com-pared to WT cells. An association of Me118 with emerin was observed in HGPS, but not in WT cells.Conclusion: Based on these findings, we propose that PIPPs, along with associated lamina proteins may form a pathogenic progerin-containing protein complex.

  4. Sister Carrie in China

    Institute of Scientific and Technical Information of China (English)

    殷希

    2015-01-01

    Sister Carrie has received many Chinese scholar's attention, and it has quantity relevance researches. Therefore, it is valuable to study why it is popular in China and it's education meaning for Chinese people. In addition, to analysis the domestic re-searches and find it's exist problems can help us make a new breakthrough from the study.

  5. Development of urbanization in arid and semi arid regions based on the water resource carrying capacity -- a case study of Changji, Xinjiang

    Science.gov (United States)

    Xiao, H.; Zhang, L.; Chai, Z.

    2017-07-01

    The arid and semiarid region in China where have a relatively weak economic foundation, independent development capacity, and the low-level of urbanization. The new urbanization within these regions is facing severe challenges brought by the constraints of resources. In this paper, we selected the Changji Hui Autonomous Prefecture, Xinjiang Uyghur Autonomous Region as study area. We found that agricultural planting structure is the key water consumption index based on the research about the main water demands of domestic, agriculture and industry. Finally, we suggest that more attentions should be paid to the rational utilization of water resources, population carrying capacity, and adjust and upgrade the industrial structure, with the purpose of coordination with the Silk Road Economic Belt.

  6. Research on Land Use Decısıons to Carry out Remote Sensıng:A Case Study on Gediz Delta

    Directory of Open Access Journals (Sweden)

    O. YılmazÜ. Erdem

    2011-01-01

    Full Text Available Gediz Delta is place of empties itself into the sea of Gediz River. It’s one of the important wetland of Turkey which under the protection of Ramsar Convention. It has lots of lagoones, salt marshes, freshwater marshes, large saltpans and also ornitotourism place “Kuş Cenneti”. Gediz Delta has rich flora and fauna biodiversity because of this it’s important place for natural life sustainability. Gediz river has carried pollution factors from 4 cities. In addition İzmir city urbanization pressure has been threated the area where is 44 km far form city center. Thus It’s vital important to determination of landuse decisions and planning.In this study has been evaluated of Gediz Delta landuse decisions by remote sensing techniques. During the study, research area and its surrounds has been searched for natural, cultural and agricultural structure. In addition, to obtain natural structure data’s has been used Landsat 7 ETM satellite image analyses techniques and geographical information systems. Corine (Coordination of Information on Environment standarts, which European Environmental Agency standarts for landuse situation, have been used as landuse standarts. In this study landuse decisions have been determinated. It can base on planning process.

  7. A 36 years old woman with Hutchinson-Gilford Progeria Syndrome: a case report

    Directory of Open Access Journals (Sweden)

    Akrami S M

    2007-10-01

    Full Text Available Background: Hutchinson-Gilford Progeria Syndrome (HGPS is a very rare genetic disorder with a frequency of 1 in 8 million live births. It is characterised by premature aging phenotype. The median age at death is 13.4 years. It is an autosomal dominat disease due to a de novo point mutation in the Lamin A gene exon 11 in the majority of cases. More than 100 cases have been reported world wide."nCase report: We describe here an exceptionally long-lived patient with HGPS, who is alive at age 36. She was referred by a cardiologist to our endocrinology clinic to be worked up for presence of a metabolic or genetic disorder before a heart surgery."nResults: Having more attention of clinicians about very rare diseases and referring the patients to geneticist are the main goals of this case report as well as describing the disease.

  8. Sex reversal syndrome in the horse: four new cases of feminization in individuals carrying a 64,XY SRY negative chromosomal complement.

    Science.gov (United States)

    Anaya, Gabriel; Moreno-Millán, Miguel; Bugno-Poniewierska, Monika; Pawlina, Klaudia; Membrillo, Alberto; Molina, Antonio; Demyda-Peyrás, Sebastián

    2014-12-10

    Horses are characterized as having a greater rate of chromosomal abnormalities than other species, which are mainly related to the sex chromosome pair and produce a series of different anomalies known as disorders in sexual development (DSD). In the present study, three Pura Raza Española (PRE) and one Menorquín (MEN) horses were studied and an incompatibility in their genetic and phenotypic sex were detected. Animals were karyotyped by conventional and molecular cytogenetic analyses and characterized using genomic techniques. Although all individuals, were totally unrelated, these animals had the same abnormality (64,XY SRY negative DSD) despite having an anatomically normal external mare phenotype. Therefore, this syndrome could remain undiagnosed in a large percentage of cases because the physiological and morphological symptoms are rare. In the present study, a slight gonadal dysgenesis was observed only in older individuals. Interestingly this chromosomal abnormality has been previously reported less than twenty times, and never in the PRE or MEN horses. With the present research, it is demonstrated that the use of genetic and cytogenetic diagnostic tools in veterinary practice could be an important complementary test to determine the origin of unexplained reproductive failures among horses. Copyright © 2014 Elsevier B.V. All rights reserved.

  9. The Strategies of Carrying out Cooperative Learning Based on Chemical Case Study%基于化学学案开展互助合作学习的策略

    Institute of Scientific and Technical Information of China (English)

    陆茜; 沈理明

    2011-01-01

    论文阐述在化学教学中采用在学案基础上进行互助合作学习的策略。包括通过学案搭建引导学生互助合作学习的"脚手架",让学生通过学案明确教学目标、进行课前预习、开展课堂互助合作学习、检测学生学习效果等。%The paper described the strategies used in teaching chemistry which of carrying out cooperative learning based on case study. Including through case study building "scaffolding" which could guide students to carry out cooperative learning, the preview, mutual assistance and cooperation of classroom learning, testing students' learning effects.

  10. "Christian carrying goomies".

    Science.gov (United States)

    1994-01-01

    Dr. Passingan Usurup tells critics of his pragmatic approach on condom promotion that he is a Christian carrying condoms for Christ. He is head of the University of Papua New Guinea Medical Center and is credited with developing an AIDS/HIV policy for the Papua New Guinea Defence Force. The condoms were named Goomy and promoted at launching in 1992 in a blue packet under the slogan "The bond that guards." Goomy was chosen as the name because it is pidgin for rubber, chewing gum, and anything associated with rubber. Blue packets were chosen over the calls of most soldiers for a camouflage design because of its universal appeal as the color of the sea and sky and because it was the preference of women in the airlines. Once firmly ensconced in his role at the University, Usurup plans to develop a policy for students and staff and help to conduct AIDS prevention and education activities on campus. He will encourage students to test for HIV rather than highlighting the gloom and doom of infection and disease.

  11. Measuring Social Carrying Capacity: An Exploratory Study

    OpenAIRE

    López-Bonilla, Jesús Manuel; López-Bonilla, Luis Miguel

    2007-01-01

    The tourist carrying capacity commands a growing interest given that it is closely linked with sustainable tourist development. The justification of the utility of this concept is given by means of a simple and efficient methodological proposal, by analysing the social carrying capacity. To this end, an empirical application is carried out in the Western Andalusia. In some of the cases analysed, the satisfaction of the tourist is found to decline when the levels of the tourist use are higher ...

  12. 242例未行准分子激光原位角膜磨镶术患者角膜因素分析%Analysis of 242 cases which unable to carry out LASIK

    Institute of Scientific and Technical Information of China (English)

    王林; 张庆生; 王忠海

    2014-01-01

    Objective Analyze the cornea factors which result in unable to carry out the LASIK operation .Method Do retrospective analysis research and summarize 242 patients’ medical records who did not undergo LASIK because of factors in the cornea.Results In total 242 cases, 112 patient’s corneal thickness less than normal that account for the to-tal 46.3%, 87 cases of suspected keratoconus that make up 36.0%of the total, 5 cases (2.1%) of keratoconus , 25 ca-ses (10.3%) are wearing orthokeratology lens , 8 cases (3.3%) are fell ill with keratitis, 5 cases (2.0%) are due to some other corneal problems .Conclusion Corneal factors are the main reasons for unable to carry out the LASIK opera-tions , carry out strict check work on patients ’ cornea to know the relevant indications and contraindications before the oper -ation is very critical to improve the safety of the LASIK operations .%探讨因角膜因素未行准分子激光原位角膜磨镶术( LASIK)的原因。方法回顾分析242例因角膜因素未行LASIK的原因。结果在242例因角膜因素未行LASIK中,角膜厚度不足112例(46.3%),可疑圆锥角膜87例(36.0%),圆锥角膜5例(2.1%),佩戴角膜塑形镜25例(10.3%),角膜炎8例(3.3%),其它角膜因素5例(2.0%)。结论角膜因素是未行LASIK的主要原因,严格的手术前角膜筛查,掌握手术的适应证与禁忌证,可以提高LASIK手术的安全性。

  13. On fast carry select adders

    Science.gov (United States)

    Shamanna, M.; Whitaker, S.

    1992-01-01

    This paper presents an architecture for a high-speed carry select adder with very long bit lengths utilizing a conflict-free bypass scheme. The proposed scheme has almost half the number of transistors and is faster than a conventional carry select adder. A comparative study is also made between the proposed adder and a Manchester carry chain adder which shows that the proposed scheme has the same transistor count, without suffering any performance degradation, compared to the Manchester carry chain adder.

  14. On fast carry select adders

    Science.gov (United States)

    Shamanna, M.; Whitaker, S.

    This paper presents an architecture for a high-speed carry select adder with very long bit lengths utilizing a conflict-free bypass scheme. The proposed scheme has almost half the number of transistors and is faster than a conventional carry select adder. A comparative study is also made between the proposed adder and a Manchester carry chain adder which shows that the proposed scheme has the same transistor count, without suffering any performance degradation, compared to the Manchester carry chain adder.

  15. Analysis of a case with typical Hutchinson-Gilford progeria syndrome with scleroderma-like skin changes and review of literature%伴硬皮病样改变的典型Hutchinson-Gilford早老综合征一例并文献复习

    Institute of Scientific and Technical Information of China (English)

    黄姗; 梁雁; 吴薇; 付溪; 廖立红; 罗小平

    2014-01-01

    subcutaneous fat.LMNA gene analysis showed that the affected-infant carried typical heterozygous mutation:c.1824C >T (p.G608G),while his parents were normal.At the age of 13 months,X-rays showed short distal phalanges and clavicles with acroosteolysis.After following up for 15 months,his appearance of progeria became more apparent.As far as we know,there are only 2 cases of classical HGPS confirmed by gene analysis in China.Conclusion Classical HGPS should be considered when infants appeared with sclerodermatous skin.Genetic analysis could help to diagnose classical HGPS as early as possible and avoid unnecessary investigations.In addition,affectedinfants need to be long term followed-up and provided genetic counseling.

  16. An Analysis of English Carrie

    Institute of Scientific and Technical Information of China (English)

    孙淑珍

    2004-01-01

    @@ Chapter Ⅰ Introduction Sitting in the rocking chair,Carrie dreams her future.This is the deep impression the novel"Sister Carrie"gives us,which is written by Theodore Dreiser(1871-1945),the great American realism writer.

  17. Optimal growth trajectories with finite carrying capacity.

    Science.gov (United States)

    Caravelli, F; Sindoni, L; Caccioli, F; Ududec, C

    2016-08-01

    We consider the problem of finding optimal strategies that maximize the average growth rate of multiplicative stochastic processes. For a geometric Brownian motion, the problem is solved through the so-called Kelly criterion, according to which the optimal growth rate is achieved by investing a constant given fraction of resources at any step of the dynamics. We generalize these finding to the case of dynamical equations with finite carrying capacity, which can find applications in biology, mathematical ecology, and finance. We formulate the problem in terms of a stochastic process with multiplicative noise and a nonlinear drift term that is determined by the specific functional form of carrying capacity. We solve the stochastic equation for two classes of carrying capacity functions (power laws and logarithmic), and in both cases we compute the optimal trajectories of the control parameter. We further test the validity of our analytical results using numerical simulations.

  18. Optimal growth trajectories with finite carrying capacity

    Science.gov (United States)

    Caravelli, F.; Sindoni, L.; Caccioli, F.; Ududec, C.

    2016-08-01

    We consider the problem of finding optimal strategies that maximize the average growth rate of multiplicative stochastic processes. For a geometric Brownian motion, the problem is solved through the so-called Kelly criterion, according to which the optimal growth rate is achieved by investing a constant given fraction of resources at any step of the dynamics. We generalize these finding to the case of dynamical equations with finite carrying capacity, which can find applications in biology, mathematical ecology, and finance. We formulate the problem in terms of a stochastic process with multiplicative noise and a nonlinear drift term that is determined by the specific functional form of carrying capacity. We solve the stochastic equation for two classes of carrying capacity functions (power laws and logarithmic), and in both cases we compute the optimal trajectories of the control parameter. We further test the validity of our analytical results using numerical simulations.

  19. Carrying Capacity:An Overview

    Institute of Scientific and Technical Information of China (English)

    Chen Shaofeng

    2004-01-01

    The concept of carrying capacity is derived from ecology, with widespread contentions of its theoretical connotations and applications in the international academic community, especially the impact of human activities on the environment.Disputes on carrying capacity have been occurring not only among biologists and ecologists, but also among mainstream economists. Based on their efforts,the author makes an attempt to describe its origin,connotations, problems, measurement, and at the same time note the latest international progress in this field.

  20. Naturalistic Elements in Sister Carrie

    Institute of Scientific and Technical Information of China (English)

    刘艳晖

    2007-01-01

    @@ Theodore Dreiser is considered to be a controversial writer.His first novel.Sister Carrie makes a new way of presenting re-ality.This paper discusses the naturalistic elements from the de-tailed description of the environment in that society.

  1. Properties of Carry Value Transformation

    Directory of Open Access Journals (Sweden)

    Suryakanta Pal

    2012-01-01

    Full Text Available Carry Value Transformation (CVT is a model of discrete deterministic dynamical system. In the present study, it has been proved that (1 the sum of any two nonnegative integers is the same as the sum of their CVT and XOR values. (2 the number of iterations leading to either CVT=0 or XOR=0 does not exceed the maximum of the lengths of the two addenda expressed as binary strings. A similar process of addition of modified Carry Value Transformation (MCVT and XOR requires a maximum of two iterations for MCVT to be zero. (3 an equivalence relation is shown to exist on Z×Z which divides the CV table into disjoint equivalence classes.

  2. Error propagation in energetic carrying capacity models

    Science.gov (United States)

    Pearse, Aaron T.; Stafford, Joshua D.

    2014-01-01

    Conservation objectives derived from carrying capacity models have been used to inform management of landscapes for wildlife populations. Energetic carrying capacity models are particularly useful in conservation planning for wildlife; these models use estimates of food abundance and energetic requirements of wildlife to target conservation actions. We provide a general method for incorporating a foraging threshold (i.e., density of food at which foraging becomes unprofitable) when estimating food availability with energetic carrying capacity models. We use a hypothetical example to describe how past methods for adjustment of foraging thresholds biased results of energetic carrying capacity models in certain instances. Adjusting foraging thresholds at the patch level of the species of interest provides results consistent with ecological foraging theory. Presentation of two case studies suggest variation in bias which, in certain instances, created large errors in conservation objectives and may have led to inefficient allocation of limited resources. Our results also illustrate how small errors or biases in application of input parameters, when extrapolated to large spatial extents, propagate errors in conservation planning and can have negative implications for target populations.

  3. Two paediatric cases of skin and soft-tissue infections due to clindamycin-resistant Staphylococcus aureus carrying a plasmid-encoded vga(A) allelic variant for a putative efflux pump.

    Science.gov (United States)

    Qin, Xuan; Poon, Brian; Kwong, Justin; Niles, Denver; Schmidt, Byron Z; Rajagopal, Lakshmi; Gantt, Soren

    2011-07-01

    Two clinical Staphylococcus aureus isolates were investigated due to their unusual antimicrobial susceptibility pattern, i.e. erythromycin-susceptible but clindamycin-resistant. These isolates harboured identical copies of a plasmid-borne vga(A)(LC) gene not previously described in S. aureus. The native plasmids carrying vga(A)(LC) were transferable to a susceptible laboratory strain of S. aureus in vitro, in which they conferred resistance patterns similar to the parent isolates. Copyright © 2011 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.

  4. Infections That Pets Carry (For Parents)

    Science.gov (United States)

    ... Your 1- to 2-Year-Old Infections That Pets Carry KidsHealth > For Parents > Infections That Pets Carry ... how to protect your family from infections. How Pets Spread Infections Like people, all animals carry germs . ...

  5. A Brief Analysis of Sister Carrie's Character

    Science.gov (United States)

    Yu, Hanying

    2010-01-01

    Carrie is always dreaming while the rocking chair is rocking again and again, this is the deep impression on us after we read "Sister Carrie" which is the first novel of Theodore Dreiser. In this novel the protagonist Sister Carrie is a controversial person. This paper tries to analyze the character of Sister Carrie in order to find out…

  6. Subjective experiences of a yogo teacher with reference to health support activities carried out in the first year after the Great East Japan Earthquake: A case study based on a narrative approach.

    Science.gov (United States)

    Aoyagi, Chiharu; Kanaizumi, Shiomi; Shikama, Kumiko; Sakou, Keiko

    2017-01-01

    Objectives To offer an empirical lens-based on the account of a yogo teacher employed at a temporary school in the community where she was relocated after experiencing the Great East Japan Earthquake alongside her students-into the subjective experience of health support activities carried out during the year immediately following the disaster.Method An interview was conducted with one yogo teacher who experienced the Great East Japan Earthquake, employed at a public junior high school in the region to where she was evacuated. Analysis involved a narrative approach whereby the yogo teacher's story was rewritten as a story in chronological order.Results The immediate course of events following the disaster was divided into three periods and examined. Period 1: The yogo teacher first experienced the earthquake and was forced to evacuate alongside her students, during which time she felt strong [sense of loss] and [sense of despair]. Period 2: At the reopening of the school in temporary classrooms, she believed her top priority was doing what she could as a yogo teacher and contributing to reopening the school, while working with other teaching staff to make the most of their surroundings. The school's reopening brought a significant sense of security and joy to students. This led her to [finding hope], and she recovered her positive attitude. Subsequently, problems manifested such as bullying and violence. She believed that [being there for the children] was the most important thing she could do as a yogo teacher and continued to provide [emotional care]. Period 3: At the time of completion of a temporary school building, she was [confused and explored] the delay of the children's recovery from emotional problems. She coordinated with a university professor of psychology to conduct classes to alleviate students' tension and stress using strategies such as relaxation techniques. She realized the importance of initiatives that involve [a keen sense of connection

  7. 25 CFR 167.6 - Carrying capacities.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Carrying capacities. 167.6 Section 167.6 Indians BUREAU... Carrying capacities. (a) The Commissioner of Indian Affairs on June 26, 1943, promulgated the authorized carrying capacity for each land management district of the Navajo Reservation. (b) Recommended...

  8. 7 CFR 1437.402 - Carrying capacity.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Carrying capacity. 1437.402 Section 1437.402... Determining Coverage of Forage Intended for Animal Consumption § 1437.402 Carrying capacity. (a) CCC will establish a carrying capacity for all grazed forage present in the county for purposes of administering...

  9. A FEMINIST READING OF SISTER CARRIE

    Institute of Scientific and Technical Information of China (English)

    高陈科

    2011-01-01

    In the history of American literature, Sister Carrie has always been a controversial character. The critics regard Carrie either as a "fallen woman" or as a "new women". This thesis aims to offer a feminist reading of the image of Sister Carrie in the con

  10. Local Dynamic Stability Associated with Load Carrying

    Directory of Open Access Journals (Sweden)

    Jian Liu

    2013-03-01

    Conclusion: Current study confirmed the sensitivity of local dynamic stability measure in load carrying situation. It was concluded that load carrying tasks were associated with declined local dynamic stability, which may result in increased risk of fall accident. This finding has implications in preventing fall accidents associated with occupational load carrying.

  11. [Pathological features of hepatocellular carcinoma carrying hepatitis C virus antigen].

    Science.gov (United States)

    Liu, B; Zhu, S; Zhang, X

    1997-10-01

    To analyze the pathological features of hepatocellular carcinomas (HCCs) carrying different hepatitis virus antigens histopathologically and systematically. PAP and ABC kits were used in the immunohistochemical study, and CAS-200 System was applied in the image cytometry. As compared with HCCs carrying HBV marker(s), the HCCs carrying HCV marker showed more cases of clear cell type (7/9 vs 4/33), better differentiation of cancers, less necrosis of hepatocytes, milder lymphocyte infiltration in the hepatic sinuses or periportal areas (P < 0.01), higher incidence of bile ductule damages, and bore a close relation to the formation of lymphoid follicle in the surrounding tissues (P < 0.05). These patients were elder, with lower grade of symptoms and better prognosis after operation. HCCs carrying only HCAg have different pathological features and clinical characteristics from which carrying HBV marker(s). The results of image cytometry are in accordance with the biological behaviour of HCC.

  12. Sister Carrie:A Material Pursuer

    Institute of Scientific and Technical Information of China (English)

    马春花

    2015-01-01

    Sister Carrie dramatized by Dreiser is totally a material pursuer. She is selfish and accumulates money in a crazy way. What she does inevitably centers on materials. Living with Drouet and later Hurstwood, Carrie gets what she wants and enjoys the luxurious life in an easy way. However, with the satisfaction of some of her desires, Carrie ’s desires grow and expand. With enough food and clothes, she needs luxury. Hurstwood’s failure in business leads Carrie to the stage and finally she makes a suc⁃cess and becomes a famous actress in Broadway. She gets more money, but her desires grow even higher. Nothing can satisfy her. In this essay, the author tries to analyze Carrie according to Freud’s and Guo Weilu’s theories and prove that Carrie is totally a material pursuer.

  13. ENVIRONMENTAL CARRYING CAPACITY BASED ON SPATIAL PLANNING

    OpenAIRE

    Luthfi Muta'ali

    2013-01-01

    The aims of this research were to examine environmental carrying capacity analyzed based on aspects of spatial planning and eco-region. The result showed that Kulonprogo Regency has low value of environmental carrying capacity and can only support as much as 79.81% of its total population. Analysis of variance showed significant difference of environmental carrying capacity of protected and cultivated area. The main factor among 12 variables determining the degree of environmen...

  14. The curious case of ageing

    OpenAIRE

    Dilip Gude; Aslam Abbas; MAW Zubair

    2013-01-01

    Hutchinson-Gilford progeria syndrome (HGPS) is an extremely rare hereditary disease characterized by multisystem involvement. Although the patients may sport normal intelligence, the disease takes a considerable toll both physically and psychologically resulting in a debilitating state. It may also be compounded by catastrophic/fatal events of accelerated atherosclerosis such as stroke and myocardial infarction. We discuss our experience with HGPS and review the literature.

  15. The curious case of ageing

    Directory of Open Access Journals (Sweden)

    Dilip Gude

    2013-01-01

    Full Text Available Hutchinson-Gilford progeria syndrome (HGPS is an extremely rare hereditary disease characterized by multisystem involvement. Although the patients may sport normal intelligence, the disease takes a considerable toll both physically and psychologically resulting in a debilitating state. It may also be compounded by catastrophic/fatal events of accelerated atherosclerosis such as stroke and myocardial infarction. We discuss our experience with HGPS and review the literature.

  16. Bivalve carrying capacity in coastal ecosystems

    NARCIS (Netherlands)

    Dame, R.F.; Prins, T.C.

    1998-01-01

    carrying capacity of suspension feeding bivalves in 11 coastal and estuarine ecosystems is examined. Bivalve carrying capacity is defined in terms of water mass residence time, primary production time and bivalve clearance time. Turnover times for the 11 ecosystems are compared both two and three di

  17. Comments on the image of Sister Carrie

    Institute of Scientific and Technical Information of China (English)

    张楠

    2016-01-01

    Thedore Oreiser was one of America's greatest writers and one of his famous masterpieces is Sister Carrie. the heroin of the novel was a country girl who struggled for success and finally became a movie star. Analysis on the image of Carrie is of practical significance to the country girls swarming into the city nowdays in our country.

  18. Carrie Chapman Catt and Woman Suffrage.

    Science.gov (United States)

    Hardesty, Carolyn, Ed.

    1989-01-01

    Most of the material for this issue of the "Goldfinch," which explores the life of Carrie Chapman Catt, came from the archives of the State Historical Society of Iowa. Carrie Chapman Catt (1859-1947) was an Iowan who advocated woman suffrage and spent 26 years actively working for that cause. The issue contains a biography of Catt, and…

  19. Parallelization of Reversible Ripple-carry Adders

    DEFF Research Database (Denmark)

    Thomsen, Michael Kirkedal; Axelsen, Holger Bock

    2009-01-01

    The design of fast arithmetic logic circuits is an important research topic for reversible and quantum computing. A special challenge in this setting is the computation of standard arithmetical functions without the generation of \\emph{garbage}. Here, we present a novel parallelization scheme...... wherein $m$ parallel $k$-bit reversible ripple-carry adders are combined to form a reversible $mk$-bit \\emph{ripple-block carry adder} with logic depth $\\mathcal{O}(m+k)$ for a \\emph{minimal} logic depth $\\mathcal{O}(\\sqrt{mk})$, thus improving on the $mk$-bit ripple-carry adder logic depth $\\mathcal......{O}(m\\cdot k)$. The underlying mechanisms of the parallelization scheme are formally proven correct. We also show designs for garbage-less reversible comparison circuits. We compare the circuit costs of the resulting ripple-block carry adder with known optimized reversible ripple-carry adders in measures...

  20. The Concept of Carrying Capacity in Tourism

    Directory of Open Access Journals (Sweden)

    Josef Zelenka

    2014-05-01

    Full Text Available Carrying capacity is often pragmatically, theoretically as well as purely intuitively considered as a concept in the context of tourism sustainability. The carrying capacity application has the greatest potential in protected areas, in frequently visited cultural and natural attractions, and in relation to sustaining of the lifestyle of the local community and tourism destination potential in general. Despite its importance, partial applications, determination of basic theoretical principles, and specifying connection to the other theoretical concepts in tourism (particularly destination life cycle, LAC concept, visitors management, there still is a rightful opinion of some authors suggesting that there is no consistent theory of tourism carrying capacity. This theory would be the base for sophisticated practical carrying capacity applications. This paper is therefore focused on introduction of the theoretical concept of carrying capacity, which can be discussed and possibly further elaborated.

  1. Sister Carrie, an Adherent of Desires

    Institute of Scientific and Technical Information of China (English)

    裴水妹

    2007-01-01

    Sister Carrie is one of the most controversial characters in American literature.Thought as a "fallen woman" firstly,she was defined as a "new woman" by some critics later. However, by digging into the motivaton behind the whole process of Carrie's "success", the relationship between Carrie and her creator (the author), the social conditions of then American, it can be found that Carrie has never been free-standing on her thought and she has never found her real-sdf even after becoming a famous actress. In a society dominated by mass consumerism Carrie is only an adherent of her own desires. She also is a representative of all those country girls flooded into cities, a symbol and a sacrifice of the urbanization of America in a time countryside was overcome by cities.

  2. Carrying Network Accessing Architecture and Strategy Based on Business Differentiation

    Directory of Open Access Journals (Sweden)

    Yanyan Han

    2013-07-01

    Full Text Available Due to the abilities of real-time sensing and information sharing, Wireless Sensor Network (WSN has been applied in more and more fields. Basing on the emergence of Internet of Things (IoT, the issue about heterogeneous network integration is becoming more important. We first analyze the new businesses that arise recently for cell phone users as well as the potential effect on carrying network. After that we mainly discuss the influence on traditional carrying network for WSN accessing and taking concurrent businesses as the study case, common access architecture from WSN to carrying network is constructed, which makes use of business differentiation. Furthermore, we propose the idea of tortuous access from WSN to the gateway in the carrying network to avoid congested paths with simulation and verification. Finally, we conclude the possible impacts for the integration of these two networks and present possible solutions.

  3. General Measurement of Marine Ecological Carrying Capacity and Biological Immunology :A Case Study in Liaoning Province%基于生物免疫学理论的海域生态承载力综合测度研究——以辽宁省为例

    Institute of Scientific and Technical Information of China (English)

    狄乾斌; 吴佳璐; 张洁

    2013-01-01

    本研究根据海洋生态承载力对海洋生态系统健康的作用与人体免疫力对人体健康的维系作用的相似性,利用生物免疫学原理,构建了辽宁省海域生态承载状态综合测度指标体系,并进行了辽宁省海域2000年-2009年10年间的综合测度研究.结果表明:辽宁省海域自然承载力指数和承载力潜力指数整体分别呈下降和上升趋势,但是资源环境承载力总体却是波动下降趋势;人口与社会经济发展压力指数在2000年-2005年间波动较小,2006年呈现大幅度上升,之后稍有下降,总体上后期比前期增长较多.近几年来,辽宁省海域资源环境承载力的可持续发展状态较差,需要在海洋产业结构调整、污染治理和海洋科研方面加大力度.%Research on carrying capacity, regarded as the basis for the sustainable development of resources and the environment, is gaining more and more attention. With the growing popularity of marine issues, scholars are following the field of marine carrying capacity closely. Studies on marine carrying capacity are instrumental in planning economic development of coastal regions; however, most research findings are quantitative rather than qualitative. Because of the role of marine ecological carrying capacity in marine ecosystems is similar to the role of the human immune system in human health, we introduce a model of biological immunology using the Liaoning marine system as a case study. Numerical models such as entropy, discriminant models of sustainable development and fuzzy membership functions were used to calculate related index values. Results show that from 2000-2009 the natural carrying capacity index increased and the potential capacity index decreased, while overall carrying capacity experienced a floating decline. From 2000-2005 the pressure index of population and economic development was relatively stable, but after 2006 it encountered a sharp rise and then declined slightly with

  4. Gun Carrying by High School Students in Boston, MA: Does Overestimation of Peer Gun Carrying Matter?

    Science.gov (United States)

    Hemenway, David; Vriniotis, Mary; Johnson, Renee M.; Miller, Matthew; Azrael, Deborah

    2011-01-01

    This paper investigates: (1) whether high school students overestimate gun carrying by their peers, and (2) whether those students who overestimate peer gun carrying are more likely to carry firearms. Data come from a randomly sampled survey conducted in 2008 of over 1700 high school students in Boston, MA. Over 5% of students reported carrying a…

  5. Gun Carrying by High School Students in Boston, MA: Does Overestimation of Peer Gun Carrying Matter?

    Science.gov (United States)

    Hemenway, David; Vriniotis, Mary; Johnson, Renee M.; Miller, Matthew; Azrael, Deborah

    2011-01-01

    This paper investigates: (1) whether high school students overestimate gun carrying by their peers, and (2) whether those students who overestimate peer gun carrying are more likely to carry firearms. Data come from a randomly sampled survey conducted in 2008 of over 1700 high school students in Boston, MA. Over 5% of students reported carrying a…

  6. Carry Select Adder Circuit with A Successively Incremented Carry Number Block

    OpenAIRE

    Deepak; Bal Krishan

    2014-01-01

    This paper reports a conditional carry select (CCS) adder circuit with a successively-incremented-carry-number block (SICNB) structure for low-voltage VLSI implementation. Owing to the successively-incremented-carry-number block (SICNB) structure, the new 16-bit SICNB CCS adder provides a 37% faster speed as compared to the conventional conditional Carry select adder based on the SPICE results

  7. Effects of carrying methods and box handles on two-person team carrying capacity for females.

    Science.gov (United States)

    Wu, Swei-Pi; Chang, Shu-Yu

    2010-07-01

    This study used a psychophysical approach to examine the effects of carrying methods and the presence or absence of box handles on the maximum acceptable weight carried and resulting responses (heart rate and rating of perceived exertion) in a two-person carrying task. After training, 16 female subjects performed a two-person carrying task at knuckle height for an 8-h work period. Each subject performed 4 different carrying combinations two times. The independent variables were carrying methods (parallel and tandem walking) and box handles (with and without handles). For comparison with two-person carrying, the subjects also performed one-person carrying. The results showed that the maximum acceptable weight carried (MAWC), heart rate (HR), and rating of perceived exertion (RPE) were significantly affected by the presence of box handles. However, the subjects' MAWC, HR, and RPE values were not significantly influenced by the carrying methods. The test-retest reliability of the psychophysical approach was 0.945. The carrying efficiency of two-person carrying was 96.2% of the one-person carrying method. In general, the use of box with handles allows the subjects to carry a higher MAWC (with lower HR and RPE) compared to carrying boxes without handles.

  8. Gravitational waves carrying orbital angular momentum

    CERN Document Server

    Bialynicki-Birula, Iwo

    2015-01-01

    Spinorial formalism is used to map every electromagnetic wave into the gravitational wave (within the linearized gravity). In this way we can obtain the gravitational counterparts of Bessel, Laguerre-Gauss, and other light beams carrying orbital angular momentum.

  9. POPULATION DENSITIES AND THE RANGE-CARRYING ...

    African Journals Online (AJOL)

    CAPACITY FOR LARGE MAMMALS IN QUEEN ELIZABETH ... The highest known densities oflarge terrestrial mammals occur on the grasslands in ...... It is estimated that the proper average biomass carrying capacity for the several herbivore.

  10. Transgenic cassava lines carrying heterologous alternative oxidase ...

    African Journals Online (AJOL)

    To screen positive lines for gene function, leaf lobes from two transgenic lines with a line carrying an empty vector and the wild type were subjected to somatic embryogenesis (SE), a known oxidative ... African Journal of Biotechnology Vol.

  11. A Naturalistic Reading of Sister Carrie

    Institute of Scientific and Technical Information of China (English)

    谈月

    2016-01-01

    Sister Carrie is well known as the works in which naturalism attained maturity in America. Up until now, the relevant research on Dreiser and his Sister Carrie abroad and at home is primarily concerned with the frustration of American dream, the naturalistic thoughts and pessimism. The paper attempts to study it from naturalistic point of view and explain how environmental, hereditary factors and the idea of“survival of the fittest”influence Carrie’s fate.

  12. Effects of box handle position and carrying range on bi-manual carrying capacity for females.

    Science.gov (United States)

    Wu, Swei-Pi; Loiu, Yi; Chien, Te Hong

    2015-01-01

    This study utilizes a psychophysical approach to examine the effects on carrying capacity for bi-manual carrying tasks involving different handle positions and carrying ranges. A total of 16 female subjects participated in the experiment in groups of two people, and each group of subjects performed the tasks in a random order with 12 different combinations of carrying task. The independent variables are handle position (upper, middle, lower) and carrying range (F-F: floor height carried to floor height, F-W: floor height carried to waist height, W-W: waist height carried to waist height, W-F: waist height carried to floor height), the dependent variable is the maximum acceptable carried weight (MAWC), heart rate (HR), and the rating of perceived exertion (RPE). The results show that the handle position has a significant effect on MAWC and overall RPE but no significant effect on HR. Carrying range has a significant effect on the MAWC and HR, but no significant effect on overall HR. The handle position and carrying range have a significant interaction on the MAWC and HR. The RPE for different body parts shows significant differences, and the hands feel the most tired. Overall, this study confirms that the lower handle position with the W-W carrying range is the best combination for a two-person carrying task.

  13. FPGA-Based Synthesis of High-Speed Hybrid Carry Select Adders

    Directory of Open Access Journals (Sweden)

    V. Kokilavani

    2015-01-01

    Full Text Available Carry select adder is a square-root time high-speed adder. In this paper, FPGA-based synthesis of conventional and hybrid carry select adders are described with a focus on high speed. Conventionally, carry select adders are realized using the following: (i full adders and 2 : 1 multiplexers, (ii full adders, binary to excess 1 code converters, and 2 : 1 multiplexers, and (iii sharing of common Boolean logic. On the other hand, hybrid carry select adders involve a combination of carry select and carry lookahead adders with/without the use of binary to excess 1 code converters. In this work, two new hybrid carry select adders are proposed involving the carry select and section-carry based carry lookahead subadders with/without binary to excess 1 converters. Seven different carry select adders were implemented in Verilog HDL and their performances were analyzed under two scenarios, dual-operand addition and multioperand addition, where individual operands are of sizes 32 and 64-bits. In the case of dual-operand additions, the hybrid carry select adder comprising the proposed carry select and section-carry based carry lookahead configurations is the fastest. With respect to multioperand additions, the hybrid carry select adder containing the carry select and conventional carry lookahead or section-carry based carry lookahead structures produce similar optimized performance.

  14. Carry Select Adder Circuit with A Successively Incremented Carry Number Block

    Directory of Open Access Journals (Sweden)

    Deepak

    2014-04-01

    Full Text Available This paper reports a conditional carry select (CCS adder circuit with a successively-incremented-carry-number block (SICNB structure for low-voltage VLSI implementation. Owing to the successively-incremented-carry-number block (SICNB structure, the new 16-bit SICNB CCS adder provides a 37% faster speed as compared to the conventional conditional Carry select adder based on the SPICE results

  15. An Optical Carry Chain Fast Adder

    Directory of Open Access Journals (Sweden)

    D. Al-Dabass

    1994-12-01

    Full Text Available A significant problem in Arithmetic Unit design and particularly for systolic arrays remains the speed attainable in achieving high speed addition. The root of the problem is carry propagation and a method is presented which is relatively independent of word length. The problem is addressed by the description of a suggested radical design involving a hybrid optical and electronic approach. The method of carry chain addition through pass gates is explained and a suggested implementation utilising Fabry-Perott resonators, optical waveguides and voltage controlled couplers is described. The design is suitable for n-stage modular expansion.

  16. Increased carrying capacity with perennial forage kochia

    Science.gov (United States)

    Carrying capacity can be increased on grass-dominated rangeland pastures by including perennial forage kochia (Kochia prostrata) as one of the plant components. The objectives of the study reported here were to compare the differences of traditional winter pastures versus pastures with forage kochi...

  17. Discussion of the feasibility of laparoscopic bile duct exploration carried out in the basic level hospital(adding 105 cases of report)%腹腔镜胆道探查术在基层医院开展的可行性探讨(附105例报告)

    Institute of Scientific and Technical Information of China (English)

    樊继龙

    2014-01-01

    Objective:To explore the feasibility of laparoscopic common bile duct exploration(LCBDE) carried out in the basic level hospital.Methods:The clinical data of 105 cases of LCBDE in department of general surgery were analyzed.Results:105 patients were completed under laparoscopy without conversions to open surgery.The operation time was 1.5~4.0 hours;the hospital stay was 8~15 days;there was no complications.Conclusion:LCBDE is safe and feasible.Through systematic training,it is feasible carried out in the basic level hospital.%目的:探讨腹腔镜胆总管探查术(LCBDE)在基层医院开展的可行性。方法:对普外科105例LCBDE的临床资料进行分析。结果:105例患者均在腹腔镜下完成,无中转开腹,手术时间1.5~4.0 h,住院时间8~15 d,无手术并发症。结论:LCBDE是安全可行的,通过系统培训,在基层医院开展是可行的。

  18. Proof-Carrying Code with Correct Compilers

    Science.gov (United States)

    Appel, Andrew W.

    2009-01-01

    In the late 1990s, proof-carrying code was able to produce machine-checkable safety proofs for machine-language programs even though (1) it was impractical to prove correctness properties of source programs and (2) it was impractical to prove correctness of compilers. But now it is practical to prove some correctness properties of source programs, and it is practical to prove correctness of optimizing compilers. We can produce more expressive proof-carrying code, that can guarantee correctness properties for machine code and not just safety. We will construct program logics for source languages, prove them sound w.r.t. the operational semantics of the input language for a proved-correct compiler, and then use these logics as a basis for proving the soundness of static analyses.

  19. Computer Simulation Instruction: Carrying out Chemical Experiments

    Directory of Open Access Journals (Sweden)

    Ibtesam Al-Mashaqbeh

    2014-05-01

    Full Text Available The purpose of this study was to investigate the effect of computer simulation Instruction (CSI on students' achievements: Carrying out chemical experiments to acquire chemical concepts for eleventh grade students. The subject of the study consisted two sections of a one girl's high school in Jordan. One section was randomly assigned to experimental group in which computer simulation Instruction (CSI was used, and the other section was randomly assigned to control group in which students were instructed by using the traditional teaching instruction. The findings indicated that there is progress on the part of the experimental group which used the computer simulation Instruction (CSI and this was reflected positively in the students’ achievement in carrying out chemical experiments to acquire chemical concepts.

  20. A decimal carry-free adder

    Science.gov (United States)

    Nikmehr, Hooman; Phillips, Braden; Lim, Cheng-Chew

    2005-02-01

    Recently, decimal arithmetic has become attractive in the financial and commercial world including banking, tax calculation, currency conversion, insurance and accounting. Although computers are still carrying out decimal calculation using software libraries and binary floating-point numbers, it is likely that in the near future, all processors will be equipped with units performing decimal operations directly on decimal operands. One critical building block for some complex decimal operations is the decimal carry-free adder. This paper discusses the mathematical framework of the addition, introduces a new signed-digit format for representing decimal numbers and presents an efficient architectural implementation. Delay estimation analysis shows that the adder offers improved performance over earlier designs.

  1. Like an eagle carries its young

    Directory of Open Access Journals (Sweden)

    Hans-Georg Wünch

    2016-04-01

    Full Text Available The picture of an eagle carrying its young on its wings (Dt 32:11 is a powerful and encouraging image of trust and security in God. It is particularly relevant for Western culture, where the eagle is a prominent symbol of power and strength. In recent years, though, the translation of the Hebrew term רֶשֶׁנ as ‘eagle’ has come into question and modern exegetes claim that it is more accurately translated as ‘vulture’. But can this really be a symbol of comfort? Furthermore, do eagles (or vultures even carry their young on their wings? This article intends to shed some light on these questions.Keywords: Old Testament; Deuteronomy; Eagle; Vulture

  2. A Feminist Reading of Sister Carrie

    Institute of Scientific and Technical Information of China (English)

    Wang; Jiatong

    2015-01-01

    In the history of American literature,Sister Carrie is the first novel of Theodore Dreiser,it impresses people deeply.Carrie,a poor country girl,becomes a famous star in a big city.She has totally changed from her hard experiences,and she becomes financially independent as a new woman when she goes through hesitation.In he whole novel,the author has planted some strong points of Carrie’s character.At the end of this paper,it analyzes woman’s status in modern time from two aspects of the improvement of female’s social status and the comparison between men and women.

  3. 后发地区生态承载力及其评价方法研究——以海峡西岸经济区为例%Ecological Carrying Capacity and Its Assessment Method in Late-Developing Regions——A Case Study in the Economic Zone on the West Side of the Straits

    Institute of Scientific and Technical Information of China (English)

    赵卫; 沈渭寿; 张慧; 孙明; 孙俊

    2011-01-01

    在区域生态承载力及其与资源、环境承载力相互关系的基础上,针对后发地区敏感的生态环境、强烈的发展愿景和以产业区域转移为主的后发优势战略,阐明了后发地区生态承载力的判定标准和衡量对象,构建了后发地区生态承载力概念模型;与区域生态系统健康评价相结合,运用多目标规划,建立了后发地区生态承载力评价模型,对海峡西岸经济区生态承载力进行了综合评价。目前海西区生态系统所承受的人类干扰总体上较轻,重点产业发展尚未对区域生态系统的结构、功能和健康等级构成威胁。若海西区土地产出率升至2007年上海市土地产出率的75%,海西区及其多数分区生态系统可以持续支撑其重点产业中长期发展。海西区生态系统的承载能力和承载状况具有显著的区域差异,有利于该地区经济社会的健康发展、生态服务功能的持续发挥和区域生态安全的有效保障。%Based on ecological carrying capacity and the relationship between ecological carrying capacity and other carrying capacity,the judgment standard and measurement object of ecological carrying capacity in late-developing regions were defined,the conceptual model of ecological carrying capacity in late-developing regions was also built,according to their sensitive eco-environment,relative slowness of socio-economic development,strong aspiration of development and late-developing strategy.The assessment method of ecological carrying capacity in late-developing regions was also established by multi-objective programming,combining with regional ecosystem health assessment.A case study was carried out in the economic zone on the west side of the Straits(called "Haixi Zone" for short),aiming at the sustainable development of key industry.Results showed that the human disturbance index of Haixi Zone was 2.68% in 2007,which is lower than the average level(3.13%) of China

  4. Information carrying capacity of a cosmological constant

    Science.gov (United States)

    Simidzija, Petar; Martín-Martínez, Eduardo

    2017-01-01

    We analyze the exchange of information in different cosmological backgrounds when sender and receiver are timelike separated and communicate through massless fields (without the exchange of light signals). Remarkably, we show that the dominance of a cosmological constant makes the amount of recoverable information imprinted in the field by the sender extremely resilient: it does not decay in time or with the spatial separation of the sender and receiver, and it actually increases with the rate of expansion of the Universe. This is in stark contrast with the information carried by conventional light signals and with previous results on timelike communication through massless fields in matter-dominated cosmologies.

  5. DESIGN OF OPTIMAL CARRY SKIP ADDER AND CARRY SKIP BCD ADDER USING REVERSIBLE LOGIC GATES

    OpenAIRE

    Praveena Murugesan; Thanushkodi Keppanagounder

    2014-01-01

    Reversible logic circuits have the ability to produce zero power dissipation which has found its importance in quantum computing, optical computing and low power digital circuits. The study presents improved and efficient reversible logic circuits for carry skip adder and carry skip BCD adder. The performance of the proposed architecture is better than the existing works in terms of gate count, garbage outputs and constant inputs. This design forms the basis for different quantum ALU and embe...

  6. Retinal oscillations carry visual information to cortex

    Directory of Open Access Journals (Sweden)

    Kilian Koepsell

    2009-04-01

    Full Text Available Thalamic relay cells fire action potentials that transmit information from retina to cortex. The amount of information that spike trains encode is usually estimated from the precision of spike timing with respect to the stimulus. Sensory input, however, is only one factor that influences neural activity. For example, intrinsic dynamics, such as oscillations of networks of neurons, also modulate firing pattern. Here, we asked if retinal oscillations might help to convey information to neurons downstream. Specifically, we made whole-cell recordings from relay cells to reveal retinal inputs (EPSPs and thalamic outputs (spikes and then analyzed these events with information theory. Our results show that thalamic spike trains operate as two multiplexed channels. One channel, which occupies a low frequency band (<30 Hz, is encoded by average firing rate with respect to the stimulus and carries information about local changes in the visual field over time. The other operates in the gamma frequency band (40-80 Hz and is encoded by spike timing relative to retinal oscillations. At times, the second channel conveyed even more information than the first. Because retinal oscillations involve extensive networks of ganglion cells, it is likely that the second channel transmits information about global features of the visual scene.

  7. Testability Synthesis for Jumping Carry Adders

    Directory of Open Access Journals (Sweden)

    Chien-In Henry Chen

    2002-01-01

    Full Text Available Synthesis for testability ensures that the synthesized circuit is testable by exploring the fundamental relationship between don't care and redundancy. With the exploration of the relationship, redundancy removal can be applied to improve the testability, reduce the area and improve the speed of a synthesized circuit. The test generation problems have been adequately solved, therefore an innovative testability synthesis strategy is necessary for achieving the maximum fault coverage and area reduction for maximum speed. This paper presents a testability synthesis methodology applicable to a top–down design method based on the identification and removal of redundant faults. Emphasis has been placed on the testability synthesis of a high-speed binary jumping carry adder. A synthesized 32-bit testable adder implemented by a 1.2 μm CMOS technology performs addition in 4.09 ns. Comparing with the original synthesized circuit, redundancy removal yields a 100% testable design with a 15% improvement in speed and a 25% reduction in area.

  8. Robust ferromagnetism carried by antiferromagnetic domain walls

    Science.gov (United States)

    Hirose, Hishiro T.; Yamaura, Jun-Ichi; Hiroi, Zenji

    2017-02-01

    Ferroic materials, such as ferromagnetic or ferroelectric materials, have been utilized as recording media for memory devices. A recent trend for downsizing, however, requires an alternative, because ferroic orders tend to become unstable for miniaturization. The domain wall nanoelectronics is a new developing direction for next-generation devices, in which atomic domain walls, rather than conventional, large domains themselves, are the active elements. Here we show that atomically thin magnetic domain walls generated in the antiferromagnetic insulator Cd2Os2O7 carry unusual ferromagnetic moments perpendicular to the wall as well as electron conductivity: the ferromagnetic moments are easily polarized even by a tiny field of 1 mT at high temperature, while, once cooled down, they are surprisingly robust even in an inverse magnetic field of 7 T. Thus, the magnetic domain walls could serve as a new-type of microscopic, switchable and electrically readable magnetic medium which is potentially important for future applications in the domain wall nanoelectronics.

  9. Efficient carry skip Adder design using full adder and carry skip block based on reversible Logic

    Directory of Open Access Journals (Sweden)

    Varun Pratap Singh

    2015-12-01

    Full Text Available In recent years, Reversible Logic is becoming more and more prominent technology having its applications in Quantum Computing, Nanotechnology, and Optical Computing. Reversibility plays an important role when energy efficient computations are considered. In this paper, binary full Adder with Design I and Design II are proposed. The performance analysis is verified using number of reversible gates, Garbage input/outputs, delay, number of logical calculations and Quantum Cost. According to the suitability of full adder design I and design II carry skip adder block is also constructed with some improvement in terms of delay in block carry generation. It is observed that Reversible carry skip Binary Adder with Design II is efficient compared to Design I

  10. 基于辅助阵元的方位依赖幅相误差最大似然自校正:针对确定信号模型%Maximum likelihood self-calibration for direction-dependent gain-phase errors with carry-on instrumental sensors:case of deterministic signal model

    Institute of Scientific and Technical Information of China (English)

    王鼎; 潘苗; 吴瑛

    2011-01-01

    Aim at the self-calibration of direction-dependent gm-phase errors in case of deterministic signal model, the maximum likelihood method(MLM) for calibrating the direction-dependent gain-phase errors with carry-on instrumental sensors was presented. In order to maximize the high-dimensional nonlinear cost function appearing in the MLM, an improved alternative projection iteration algorithm, which could optimize the azimuths and direc6on-dependent gain-phase errors was proposed. The closed-form expressions of the Cramér-Rao bound(CRB) for azimuths and gain-phase errors were derived. Simulation experiments show the effectiveness and advantage of the novel method.%针对确定信号模型条件下方位依赖幅相误差的自校正问题,给出了一种基于辅助阵元的方位依赖幅相误差最大似然自校正方法;针对最大似然估计器中出现的高维非线性优化问题,推导了一种改进型交替投影迭代算法,从而实现了信号方位和方位依赖幅相误差的优化计算.此外,还推导了信号方位和方位依赖幅相误差的无偏克拉美罗界(CRB).仿真实验结果验证了新方法的有效性和优越性.

  11. A case of familial transmission of community-acquired methicillin-resistant Staphylococcus aureus carrying the lnu(A gene in Santa Fe city, Argentina Caso de transmisión familiar de Staphylococcus aureus resistente a la meticilina adquirido en la comunidad portador del gen lnu(A en la ciudad de Santa Fe, Argentina

    Directory of Open Access Journals (Sweden)

    Emilce de los A Méndez

    2012-12-01

    Full Text Available Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA is increasingly recognized as an important pathogen causing skin and soft tissue infections as well as necrotizing pneumonia. We describe a case of familial transmission of CA-MRSA between a 6-month-old boy and his mother in Santa Fe City, Argentina. Both isolates showed an identical antimicrobial susceptibility profile, carried type IV SCCmec and harboured the pvl and the lnu(A genes. Isolates showed indistinguishable SmaI-PFGE patterns confirming their genetic relationship. These results corroborate the intrafamilial transmission of CA-MRSA and might associate this strain with the repetitive events of furunculosis within the family.Staphylococcus aureus resistente a la meticilina adquirido en la comunidad (SARM-AC es reconocido como un patógeno importante que causa infecciones de piel y partes blandas y neumonía necrotizante. Describimos un caso de transmisión familiar de SARM-AC entre un nino de 6 meses de edad y su madre en la ciudad de Santa Fe, Argentina. Ambos aislamientos mostraron idéntico perfil de sensibilidad a los antimicrobianos, tenían el SCCmec tipo IV, y contenían los genes pvl y lnu(A. Los aislamientos presentaron patrones de SmaI-PFGE indistinguibles entre sí, lo cual confirmó su relación genética. Estos resultados corroboran la transmisión intrafamiliar de SARM-AC; asimismo, este aislamiento podría asociarse con los eventos repetitivos de furunculosis en la familia.

  12. Efficient Approaches for Designing Fault Tolerant Reversible Carry Look-Ahead and Carry-Skip Adders

    CERN Document Server

    Islam, Md Saiful; begum, Zerina; Hafiz, Mohd Zulfiquar

    2010-01-01

    Combinational or Classical logic circuits dissipate heat for every bit of information that is lost. Information is lost when the input vector cannot be recovered from its corresponding output vector. Reversible logic circuit implements only the functions having one-to-one mapping between its input and output vectors and therefore naturally takes care of heating. Reversible logic design becomes one of the promising research directions in low power dissipating circuit design in the past few years and has found its application in low power CMOS design, digital signal processing and nanotechnology. This paper presents the efficient approaches for designing fault tolerant reversible fast adders that implement carry look-ahead and carry-skip logic. The proposed high speed reversible adders include MIG gates for the realization of its basic building block. The MIG gate is universal and parity preserving. It allows any fault that affects no more than a single signal readily detectable at the circuit's primary outputs...

  13. Carrying capacity in agriculture: environmental significance and some related patents.

    Science.gov (United States)

    da Silva, Alexandre M

    2009-06-01

    Agriculture is one of the most important and possibly the oldest economic activity developed by humans. This activity was developed extensively and is becoming more and more dependent on development of technologies. The goal of this manuscript was examining some patents related to technologies developed for improving crop yields. Such patents are mainly related to more efficient formulations of agrochemicals and management techniques of plants, cattle and natural resources. A brief comment is carried out about bioprospection and related problems, relating, for example the case of Cupuaçu. The article is concluded mentioning that the development of policies and management strategies that increase agricultural yield and simultaneously preserve or conserve natural resources should also be prioritized, because certainly this is the only way we have to get the real sustainability and to improve life quality abroad the world.

  14. Pallet Optimization of the Heavy Rotary Table Load Carrying System

    Science.gov (United States)

    Atapin, V. G.; Bataev, A. A.

    2016-04-01

    The pallet optimization of the heavy rotary table load-carrying system, which is a part of the multi-purpose machine, is considered in terms of the deterministic and probabilistic models. As a result of optimum design in case of the deterministic model the mass of the pallet is reduced by 35.5 % in comparison with a serial model. The evaluation of the influence of optimization problem limitations on design variables confirms the importance of rigidity criterion in relation to other criteria. Calculation for probabilistic model allows reducing the mass of the construction by 27 % in comparison with the deterministic model. Considering a work piece rigidity on the basis of a conventional work piece of the minimum rigidity (without stiffening ribs etc.) leads to reducing of the pallet mass by 22.3 % in comparison with the deterministic model.

  15. Modeling symbiosis by interactions through species carrying capacities

    Science.gov (United States)

    Yukalov, V. I.; Yukalova, E. P.; Sornette, D.

    2012-08-01

    We introduce a mathematical model of symbiosis between different species by taking into account the influence of each species on the carrying capacities of the others. The modeled entities can pertain to biological and ecological societies or to social, economic and financial societies. Our model includes three basic types: symbiosis with direct mutual interactions, symbiosis with asymmetric interactions, and symbiosis without direct interactions. In all cases, we provide a complete classification of all admissible dynamical regimes. The proposed model of symbiosis turned out to be very rich, as it exhibits four qualitatively different regimes: convergence to stationary states, unbounded exponential growth, finite-time singularity, and finite-time death or extinction of species.

  16. Rise-Time Distortion of Signal without Carrying Signal

    Science.gov (United States)

    Bukhman, N. S.

    2016-08-01

    The article deals with one-dimensional problem of rise-time distortion signal without carrying signal, that appears in the starting point intermittently, that is signal distortion at front edge or one of its derivative. The authors show that front edge of signal isn't distorted in case of propagation in unrestricted (including absorbing) area (amplitude of starting signal step or of one of its derivatives doesn't change) and move with the accuracy of vacuum light speed. The paper proves that it is the time interval shortage that causes signal loss with the route extension, but not the reduction of its starting amplitude, during which front edge of signal retains its starting value. The research presents new values for this time interval.

  17. Fault tolerant reversible logic synthesis: Carry look-ahead and carry-skip adders

    CERN Document Server

    Islam, Md Saiful; Begum, Zerina; Hafiz, Mohd Zulfiquar; 10.1109/ACTEA.2009.5227871

    2010-01-01

    Irreversible logic circuits dissipate heat for every bit of information that is lost. Information is lost when the input vector cannot be recovered from its corresponding output vector. Reversible logic circuit naturally takes care of heating because it implements only the functions that have one-to-one mapping between its input and output vectors. Therefore reversible logic design becomes one of the promising research directions in low power dissipating circuit design in the past few years and has found its application in low power CMOS design, digital signal processing and nanotechnology. This paper presents the efficient approaches for designing reversible fast adders that implement carry look-ahead and carry-skip logic. The proposed 16-bit high speed reversible adder will include IG gates for the realization of its basic building block. The IG gate is universal in the sense that it can be used to synthesize any arbitrary Boolean-functions. The IG gate is parity preserving, that is, the parity of the input...

  18. Evaluation of Water Ecological Carrying Capacity Based on Ecological Footprint Theory: A Case Study of Huzhou%基于生态足迹法的区域水生态承载力研究——以浙江省湖州市为例

    Institute of Scientific and Technical Information of China (English)

    刘子刚; 郑瑜

    2011-01-01

    本文初步界定了水生态足迹和水生态承载力的内涵,将水生态足迹分为水产品生态足迹、水资源生态足迹与水污染生态足迹,并建立了水生态足迹模型.其中,采用了Wackemagel的水产品生态足迹模型;水资源生态足迹采用了基于水资源消耗量的计算模型;采用零维模型计算污染稀释净化需水量,构建水污染生态足迹模型.最后,以扣除60%生态需水为前提建立了水生态承载力计算模型.以浙江省湖州市为例,模型计算了湖州市2000年-2007年水生态足迹和水生态承载力,结果显示,湖州市2000年-2007年水生态承载力超过水生态足迹,呈现生态盈余,但是水生态承载力波动较大,水生态足迹在不断增大;由于水产品的消费量逐年增大,水产品生态足迹在水生态足迹中所占比例也相应增大.%Ecological footprint is widely used in many countries and regions and has become an important method to evaluate ecological carrying capacity. Based on the ecological footprint model, an evaluation model on water ecological carrying capacity was built and was used to assess water ecological carrying capacity in Huzhou City, Zhejiang Province. The concept of water ecological carrying capacity was defined. Water ecological carrying capacity consists of water product footprint, water resource footprint, and water pollution footprint. The original model raised by Wackemagel was used to calculate water product footprint. Water resource footprint was divided into four third level accounts, i.e., agriculture water footprint, industrial water footprint, domestic water footprint, and other water footprint. Besides, based on the ecological footprint model, the zero-dimensional model was used to calculate water demand of pollution dilution and purification and then water pollution footprint was calculated. At last, a water carrying capacity model was built on the basis of 60% of all the water resource being necessary to

  19. Carrying Capacity of Marine Region in Liaoning Province

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Carrying capacity is one of important studies on coordinating development of population, resources, and environment. At present, the researches on it mainly concentrate on the carrying capacity for population and economy,such as the water resources carrying capacity, the land resources carrying capacity, the environment carrying capacity,etc. Based on the related theories and methods, this paper creatively proposed the concept and meaning of carrying capacity of marine region, and formed the appraisal system. According to the developing situation of marine economy of Liaoning Province in recent years, and by employing the method of the state space, this paper also measured the cartying capacity and carrying state of marine region and discussed the sustainable problems of marine economy of Liaoning. The research results show that the carrying state of marine region of Liaoning is in the state of overloading at present, but taking a favorable turn.

  20. Delay Efficient 32-Bit Carry-Skip Adder

    OpenAIRE

    Yu Shen Lin; Damu Radhakrishnan

    2008-01-01

    The design of a 32-bit carry-skip adder to achieve minimum delay is presented in this paper. A fast carry look-ahead logic using group generate and group propagate functions is used to speed up the performance of multiple stages of ripple carry adders. The group generate and group propagate functions are generated in parallel with the carry generation for each block. The optimum block sizes are decided by considering the critical path into account. The new architecture ...

  1. Spatial Structure Evolution of Urban System in the Loess Plateau Based on Ecological Carrying Capacity -A Case Study in Qingyang City%基于生态承载力的黄土高原地区城镇系空间结构演化——以庆阳市为例

    Institute of Scientific and Technical Information of China (English)

    刘海龙; 石培基; 张学斌; 张惠; 魏伟

    2013-01-01

    庆阳市位于黄土高原中部丘陵沟壑区,气候干旱,生态脆弱.运用生态承载力、城镇体系相关理论和方法,分析研究区城镇体系空间结构演化特点及趋势.采用生态弹性度、资源承载力和承载压力度、对生态承载力的演化进行综合评价,并对生态承载力与城镇空间结构的关系进行探讨.在此基础上,对研究区城镇体系空间结构进行调整优化,为脆弱生态条件下的城镇发展提供依据.%Qingyang City is located in a hilly-gully region in the central Loess Plateau,it is arid,and the ecological environment is fragile.In this paper,the spatial structure evolution of urban system in the study area was analyzed based on the ecological carrying capacity.The results showed that there was a traffic directivity in the study area during the period of 1985-2010,and the town development was restricted by the limited traffic conditions.Urban distribution was related to the distribution of water resources,and it was different from different counties.Double center pattern was gradually formed under the optimization of urban system.The ecological elastic degree,carrying capacity of resources and load pressure strength were used in the evaluation.The results showed that the ecological elastic degree and carrying capacity of resources in the study area were holistically in an ascendant trend during the period of 1985-2010.Spatial structure of the regional urban system and the ecological carrying capacity interacted,and the relationship between the ecological carrying capacity and the spatial structure of urban system was discussed.Some measures were proposed for optimizing the spatial structure of urban system in the study area based on the ecological carrying capacity in such fragile ecological environment.

  2. Interpretations of the Image of Caroline in Sister Carrie

    Institute of Scientific and Technical Information of China (English)

    钱绘

    2014-01-01

    In the history of American naturalistic literature, Sister Carrie is a representative work of this literary genre. And the protagonist of this novel Caroline has always been a controversial character. Based on Sister Carrie and the social background of that period in America, this paper discussed the various interpretations of the image of Carrie from different aspects.

  3. 46 CFR 111.105-35 - Vessels carrying coal.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Vessels carrying coal. 111.105-35 Section 111.105-35...-GENERAL REQUIREMENTS Hazardous Locations § 111.105-35 Vessels carrying coal. (a) The following are Class II, Division 1, (Zone 10 or Z) locations on a vessel that carries coal: (1) The interior of each...

  4. Radar imaging using electromagnetic wave carrying orbital angular momentum

    Science.gov (United States)

    Yuan, Tiezhu; Cheng, Yongqiang; Wang, Hongqiang; Qin, Yuliang; Fan, Bo

    2017-03-01

    The concept of radar imaging based on orbital angular momentum (OAM) modulation, which has the ability of azimuthal resolution without relative motion, has recently been proposed. We investigate this imaging technique further in greater detail. We first analyze the principle of the technique, accounting for its resolving ability physically. The phase and intensity distributions of the OAM-carrying fields produced by phased uniform circular array antenna, which have significant effects on the imaging results, are investigated. The imaging model shows that the received signal has the form of inverse discrete Fourier transform with the use of OAM and frequency diversities. The two-dimensional Fourier transform is employed to reconstruct the target images in the case of large and small elevation angles. Due to the peculiar phase and intensity characteristics, the small elevation is more suitable for practical application than the large one. The minimum elevation angle is then obtained given the array parameters. The imaging capability is analyzed by means of the point spread function. All results are verified through numerical simulations. The proposed staring imaging technique can achieve extremely high azimuthal resolution with the use of plentiful OAM modes.

  5. Delay Efficient 32-Bit Carry-Skip Adder

    Directory of Open Access Journals (Sweden)

    Yu Shen Lin

    2008-01-01

    Full Text Available The design of a 32-bit carry-skip adder to achieve minimum delay is presented in this paper. A fast carry look-ahead logic using group generate and group propagate functions is used to speed up the performance of multiple stages of ripple carry adders. The group generate and group propagate functions are generated in parallel with the carry generation for each block. The optimum block sizes are decided by considering the critical path into account. The new architecture delivers the sum and carry outputs in lesser unit delays than existing carry-skip adders. The adder is implemented in 0.25 m CMOS technology at 3.3 V. The critical delay for the proposed adder is 3.4 nanoseconds. The simulation results show that the proposed adder is 18% faster than the current fastest carry-skip adder.

  6. Evaluation of Water Resources Carrying Capacity Based on Index System with Parameter Projection Pursuit Model——A Case Study in Shijiazhuang%基于指标体系投影寻踪模型的水资源承载力评价——以石家庄为例

    Institute of Scientific and Technical Information of China (English)

    马峰; 王千; 蔺文静; 王贵玲

    2012-01-01

    石家庄市处于我国缺水严重的华北地区,水资源利用一直倍受人们的关注,水资源承载力评价可为今后的地区水资源利用及规划提供建议.文章采用了综合指标法,根据石家庄市水资源具体情况和指标体系结构特点,选取了18个指标建立水资源承载力评价指标体系及指标标准,运用投影寻踪方法建立评价模型,通过归一化处理、线性投影、构造投影指标函数和优化投影指标函数的方法,将选取的指标运用matlab数学软件进行投影寻踪分析,得到石家庄市水资源承载力等级水平为Ⅳ级,主要影响水资源承载力的指标为基本农田比例、节水灌溉率、灌溉用水有效利用系数、水资源可开发利用系数和万元工业增加值用水量等.%Shijiazhuang lies in the north of china which is seriously lack of water, and its water resources utilization always receives attention. The evaluation of water resources carrying capacity could provide advices for water resources utilization and planning in this area in future. Based on the specific conditions of water resources and the structural features of the index system in Shijiazhuang.18 indexes were selected to build the evaluation index system of water resources carrying capacity. The projection pursuit method was used to assess the model. Relying on the methods of normalization treatment, linear projection, constructing projection target function as well as optimizing projection target function, the selected indexes were analyzed using the projective pursuit method based on matlab platform. The results showed that the water resources carrying capacity level is grade IV in Shijiazhuang. The main indexes affecting the water resources carrying capacity included the basic farmland proportion, water-saving irrigation rate,effective utilization coefficient of irrigation water, utilization coefficient of available water resources, and water consumption of ten thousand yuan

  7. High performance pipelined multiplier with fast carry-save adder

    Science.gov (United States)

    Wu, Angus

    1990-01-01

    A high-performance pipelined multiplier is described. Its high performance results from the fast carry-save adder basic cell which has a simple structure and is suitable for the Gate Forest semi-custom environment. The carry-save adder computes the sum and carry within two gate delay. Results show that the proposed adder can operate at 200 MHz for a 2-micron CMOS process; better performance is expected in a Gate Forest realization.

  8. Trusted Module Acquisition Through Proof-Carrying Hardware Intellectual Property

    Science.gov (United States)

    2015-05-22

    hardware intellectual property (PCHIP) framework, which aims to ensure the trustworthiness of third-party hardware IPs utilizing formal methods. We...published in non peer-reviewed journals: Final Report: Trusted Module Acquisition Through Proof-Carrying Hardware Intellectual Property Report Title By...borrowing ideas from the proof carrying code (PCC) in software domain, in this project we introduced the proof carrying hardware intellectual property

  9. Optimal design method for fast carry-skip adders

    Science.gov (United States)

    Lee, Songjun; Swartzlander, Earl E., Jr.

    2001-11-01

    A carry-skip adder is faster than a ripple carry adder and it has a simple structure. To maximize the speed it is necessary to optimize the width of the blocks that comprise the carry skip adder. This paper presents a simple algorithm to select the size of each block. Assuming that each logic gate has a unit delay, the algorithm achieves slightly faster designs for 64 and 128 bit adders than previous methods developed by Guyot, et al. and Kantabutra.

  10. Organization and carrying out the triathlon competitions in Ukraine

    Directory of Open Access Journals (Sweden)

    Volodymyr Vodlozerov

    2016-02-01

    Full Text Available Purpose: the aim is analyzing of system of organization and carrying out the triathlon competitions in Ukraine in accordance with rules of triathlon international federation. Material & Methods: comparative analysis of process of organization and carrying out the triathlon competitions in the world and Ukraine was carried out on basis of specialist literature studying, normative base of sports organizations (triathlon federation. Results: inconsistencies were identified in competitions carried out in cold season, particularity of triathlon that intends overcoming the combined distance without time durations between stages. Conclusions: recommendation in eliminate inconsistencies that affect to performance of triathlon competitions in Ukraine was suggested.

  11. Magnetically Guiding Atoms with Current-Carrying Conductors

    Institute of Scientific and Technical Information of China (English)

    刘南春; 高伟建; 印建平

    2002-01-01

    We propose a novel magnetic guide for cold neutral atoms using some current-carrying conductors. The spatial distributions of the magnetic fields from a V-shaped or U-shaped current-carrying conductor are calculated, and the relationship between the resulting magnetic field and the parameters of the current-carrying conductors is analysed in detail. The result shows that these current-carrying conductors can be used to realize a single or a controllable double magnetic guide of cold atoms in the weak-field-seeking state, and to construct various atom-optical elements, and even to realize a single-mode atomic waveguiding under certain conditions.

  12. Research of the Tourism Destination Carrying Capacity---A Case Study of the Ancient City of Kaifeng Song Du Cultural Industry Park%旅游目的地容量测量研究--以开封宋都古城文化产业园区为例

    Institute of Scientific and Technical Information of China (English)

    孙慧娟

    2016-01-01

    随着旅游市场的快速发展和游客出游的不断增加,过多游客的涌入、景区超载拥堵现象不断出现。旅游容量作为旅游目的地规划开发的科学依据和景区管理的工具,其研究成为一个重要课题。依据木桶原理及限制性因子原理,选取空间容量、设施容量、生态容量和社会心理容量等作为旅游地容量指标,构建综合容量测量模型。以开封宋都古城文化产业园区为例,选取基本空间标准,分析得出产业园区日旅游容量为190484人次,年旅游容量69526660人次,并对产业园区旅游发展提出建议。%With the rapid development of the tourism market and the increasing of tourists ,the influx of too many tourists 、the scenic spots overload and congestions phenomenons appear constantly .Tourism carrying capacity is a scientific basis of tourism destination planning development and a tool of the scenic area management ,soit has become an important subject .Based on buckets effect and the principle of limiting factors , this paper selects space capacity , facilities capacity,ecological capacity and social psychological capacity as the basic indexes of tourism carrying capacity , and constructs comprehensive capacity measurement model.Then,this paper takes the ancient city of Kaifeng Song Du cultural industry park as an example,and selects basic space standards,analyzes and concludes that the tourism carrying capacity of industry park is 190484 person/time every-day,69526660 person/time every year,finally puts forward the proposal on its tourism development .

  13. Training to Increase Safe Tray Carrying among Cocktail Servers

    Science.gov (United States)

    Scherrer, Megan D.; Wilder, David A.

    2008-01-01

    We evaluated the effects of training on proper carrying techniques among 3 cocktail servers to increase safe tray carrying on the job and reduce participants' risk of developing musculoskeletal disorders. As participants delivered drinks to their tables, their finger, arm, and neck positions were observed and recorded. Each participant received…

  14. 46 CFR 185.340 - Vessels carrying vehicles.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Vessels carrying vehicles. 185.340 Section 185.340... TONS) OPERATIONS Miscellaneous Operating Requirements § 185.340 Vessels carrying vehicles. (a) Automobiles or other vehicles must be stowed in such a manner as to permit both passengers and crew to get...

  15. 46 CFR 122.340 - Vessels carrying vehicles.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Vessels carrying vehicles. 122.340 Section 122.340... Miscellaneous Operating Requirements § 122.340 Vessels carrying vehicles. (a) Automobiles or other vehicles must... vehicles freely in the event of fire or other disaster. The decks, where necessary, must be...

  16. 25 CFR 11.444 - Carrying concealed weapons.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Carrying concealed weapons. 11.444 Section 11.444 Indians... ORDER CODE Criminal Offenses § 11.444 Carrying concealed weapons. A person who goes about in public places armed with a dangerous weapon concealed upon his or her person is guilty of a misdemeanor unless...

  17. The Disillusion of American Dream in Sister Carrie

    Institute of Scientific and Technical Information of China (English)

    张晴

    2016-01-01

    Dreiser is a generally acknowledged writer as one of American's literary naturalists. In Sister Carrie, the author skillfully used the naturalistic writing style which incisively and vividly showed the society environment at that time. The paper states the process that how the American dream in Sister Carrie disillusioned gradually.

  18. Rapid Population Growth and Human Carrying Capacity: Two Perspectives. World Bank Staff Working Papers No. 690 and Population and Development Series No. 15.

    Science.gov (United States)

    Mahar, Dennis J., Ed.; And Others

    Two perspectives on carrying capacity and population growth are examined. The first perspective, "Carrying Capacity and Rapid Population Growth: Definition, Cases, and Consequences" (Robert Muscat), explores the possible meanings of the idea of carrying capacity under developing country conditions, looks at historical and present-day cases of…

  19. Can Structural Adjustment and Carrying Capacity Promotion Promote the Tourism Economic Growth?-Case of the Three Coastal Economic Zones in Eastern China%结构调整、承载力提升能促进旅游经济增长吗?--以东部沿海三大经济区为例

    Institute of Scientific and Technical Information of China (English)

    刘佳; 周长晓

    2015-01-01

    With China’s Bohai coastal region,Yangtze river delta and Pan-pearl river delta coastal economic zone as the object of research,this paper evaluates and measures the three regions’tourism industry structure level and tourism ecological carrying index respectively from 2003 to 2012,and reveals the spatial difference of the coast-al three regions from the perspectives of structure and bearing capacity,then analyses and tests the effect of industri-al structure and bearing capacity on the tourism economic growth.The results show that three coastal regional tourism industrial structure transformed to rationality,the overall level of development is on the rise,but the Yangtze river delta and the Pearl river delta are instability,the fluctuation trend of tourism industry in Bohai Coastal region become smaller.The tourism ecology capacity of three regions has a slight increase,but tourism ecological demand is greater than the supply,it makes the three regions’tourism ecological in the deficit state,and the tourism ecological deficit is bigger and bigger,the promotion of tourism ecological carrying capacity and the tourism industry structure adjustment can effectively promote the tourism economic growth,but the positive effect of tourism industrial structure is greater than the tourist ecological carrying capacity.%以中国环渤海、长三角、泛珠三角三大沿海经济区为研究对象,分别对2003—2012年三大地区的旅游产业结构水平和旅游生态承载力指数进行测度和评价,并从结构和承载力视角,揭示沿海三大区域空间差异特征,进而分析和检验产业结构、承载力对旅游经济增长的作用。结果表明,2003—2012年中国沿海三大区域的旅游产业结构向合理化和高度化转化,总体发展水平呈上升趋势,但长三角、珠三角波动较大表现出不稳定性,环渤海地区旅游产业结构波动趋势逐渐变小。各地区旅游生态承载力略有提升

  20. Biological Determinism and the Concept of Mental Retardation: The Lesson of Carrie Buck.

    Science.gov (United States)

    Smith, J. David

    This paper reviews the case of Carrie Buck, who was the first person sterilized (in 1927) under a Virginia law allowing sterilization of persons identified as incompetent and likely to genetically transmit physical, psychological, or social deficiencies to their offspring. This law was later upheld by the Supreme Court in Buck v. Bell, which…

  1. Estimation of Carrying Angle Based on CT Images in Preoperative Surgical Planning for Cubitus Deformities

    Directory of Open Access Journals (Sweden)

    Kim,Eugene

    2009-12-01

    Full Text Available Conventionally, the carrying angle of the elbow is measured using simple two-dimensional radiography or goniometry, which has questionable reliability. This study proposes a novel method for estimating carrying angles using computed tomography that can enhance the reliability of the angle measurement. Data of CT scans from 25 elbow joints were processed to build segmented three-dimensional models. The cross-sectional centerlines of the ulna and the humerus were traced from the 3D models, and the angle between 2 vectors formed from the centerlines of the humerus and the ulna was defined as the "three-dimensional carrying angle." These angles were compared with those measured by simple radiograph. Two cases of angular deformity were underwent surgery based on this preoperative surgical planning, and the postoperative 3D carrying angles were evaluated using the proposed method. The mean value of the calculated three-dimensional carrying angle was 20.7 degrees +/-3.61, while it was 16.3 degrees +/-3.21 based on simple radiography without statistical difference. Based on the 3D carrying angle estimations, 2 surgical cases of cubitus deformities were planned by comparison with the normal contra-lateral elbow. Postoperative angle estimations confirmed that the corrected angles were nearly identical to the planned angles for both cases. The results of this study showed that the carrying angle can be accurately estimated using three-dimensional CT and that the proposed method is useful in evaluating deformities of the elbow with high reliability.

  2. National attitudes concerning gun carrying in the United States.

    Science.gov (United States)

    Hemenway, D; Azrael, D; Miller, M

    2001-12-01

    To determine public attitudes in the United States concerning gun carrying. In the past 15 years, many state legislatures have passed laws making it easier for United States citizens to carry concealed firearms, not only on the street but into various locations, including churches and government buildings. National random digit dial telephone surveys conducted in 1996 and 1999 asked questions concerning the public's feelings of safety as more people in their community carry firearms, and whether, in the language of the question, respondents believe "regular" citizens should be allowed to carry guns into public or government buildings. Americans feel less safe rather than more safe as more people in their community begin to carry guns. By margins of at least nine to one, Americans do not believe that "regular" citizens should be allowed to bring their guns into restaurants, college campuses, sports stadiums, bars, hospitals, or government buildings. The public believes that increased gun carrying by others reduces rather than increases their safety. Overwhelmingly, the public believes that in many venues gun carrying should be prohibited.

  3. Analysis of the organisation implemented by a nuclear operator to carry out the safety of his installations: contribution of cases study; Analyse de l'organisation mise en place par un exploitant nucleaire pour assurer la surete de ses installations: l'apport des etudes de cas

    Energy Technology Data Exchange (ETDEWEB)

    Jeffroy, F.; Conte, D. [Institut de Radioprotection et de Surete Nucleaire (IRSN), 92 - Clamart (France); Boel, M. [Bertin Technologies, 78 - Montigny-le-Bretonneux (France)

    2006-07-01

    Sought to estimate if the organization implemented by a nuclear operator allowed him to provide the safety of its installations, we defined a step of analysis which approaches the organization on the formal plan of rules, structures and implemented resources, and on that one of its functioning understood through the actors collective activity. The functioning dynamics of the organization was approached from retrospective studies of case aiming to understand, from the actors contributions in the treatment of an event, the way whom the organization characteristics established resources or constraints for the actors. This approach of the organization through case studies, seems to us to have to be replaced in the debate opened at present in cognitive ergonomics, in sociology of organizations and in management. Numerous works indeed try to put in relation the activity of the 'first-line actors' and the decisions and the orientations taken at the strategic level, what supposes to be capable of articulating an analysis of the actors activity. (N.C.)

  4. Research on Psychological Carrying Capacity of Tourism Destination

    Institute of Scientific and Technical Information of China (English)

    Fan Zhiyong; Zhong Sheng

    2009-01-01

    As a part of the carrying capacity system of tourism destination,tourism psychological carrying capacity and its makeup are very important indexes which reflect the harmonious development of tourism destination develops harmoniously,but the academy has not paid enough attention to them.Based on the concept and connotation of psychological carrying capacity,this paper explains the influencing factors which affect the psychological capacity of the tourist and the resident after the acknowledged concept,and then designs a harmonious development model of tourism destination.Finally,it offers some countermeasures against the overloading psychological capacity.

  5. Global change and carrying capacity: Implications for life on Earth

    Science.gov (United States)

    Ehrlich, Paul R.; Daily, Gretchen C.; Ehrlich, Anne H.; Matson, Pamela; Vitousek, Peter

    1989-01-01

    Determining the long-term number of people that the planet can support without irreversibly reducing its ability to support people in the future, i.e., the carrying capacity of the Earth, is an exceedingly complex problem. About all that is known for certain is that, with present and foreseeable technologies, the human population has already exceeded the capacity. The reduction in carrying capacity that can be expected to result from direct human impacts on resources and the environment and from our indirect impacts of the climate system is discussed. Global warming and modeling global change and food security are also discussed with respect to carrying capacity.

  6. Global change and carrying capacity: Implications for life on Earth

    Science.gov (United States)

    Ehrlich, Paul R.; Daily, Gretchen C.; Ehrlich, Anne H.; Matson, Pamela; Vitousek, Peter

    1989-01-01

    Determining the long-term number of people that the planet can support without irreversibly reducing its ability to support people in the future, i.e., the carrying capacity of the Earth, is an exceedingly complex problem. About all that is known for certain is that, with present and foreseeable technologies, the human population has already exceeded the capacity. The reduction in carrying capacity that can be expected to result from direct human impacts on resources and the environment and from our indirect impacts of the climate system is discussed. Global warming and modeling global change and food security are also discussed with respect to carrying capacity.

  7. Estimating the recreational carrying capacity of a lowland river section.

    Science.gov (United States)

    Lorenz, Stefan; Pusch, Martin T

    2012-01-01

    Recreational boating represents a major human use of inland waters in many regions. However, boating tourism may affect the ecological integrity of surface waters in multiple ways. In particular, surface waves produced by boating may disturb freshwater invertebrates, such as interrupting the filtration activity of benthic mussels. As mussels may significantly contribute to self-purification, disturbance may have crucial impacts on water quality, and thus on water tourism. In this paper we calculate the carrying capacity of a river section for sustainable boating tourism based on the preservation of water quality. This approach is complemented by spatial and social approaches for carrying capacity estimates. The ecological carrying capacity significantly decreases with lower water levels during summer. Hence, the analysis of variables that influence the river's carrying capacity allows the formation of recommendations for management measures that integrate social, touristic and ecological aspects.

  8. Lane of parallel through carry in ternary optical adder

    Institute of Scientific and Technical Information of China (English)

    JIN Yi; HE Huacan; AI Lirong

    2005-01-01

    At the present 50 to 100 microseconds are necessary for a liquid crystal to change its state from opacity to clarity; 1.14× 10-5 microseconds are however proved to be enough for light to pass through a clarity liquid crystal device. Rooted from this great difference in time, an optical adder was constructed with parallel through carry lanes (PTCL) composed of liquid crystals. Because all carries in PTCL process in parallel, the carry delay in the ternary optical computer's adder is avoided. Eliminating the carry delay in adder of ternary optical computer by physical means, the PTCL is also applicable for other types of optical adders. Moreover a light diagram of the adder and one PTCL structure are provided.

  9. Study on Tourist Carrying Capacity Based on Matter Element Analysis

    Institute of Scientific and Technical Information of China (English)

    LiuYunguo; FanTing; LiXin; ZhouMing; WangXianhai

    2005-01-01

    This paper proposes that it is necessary to implement the concept of tourist carrying capacity to facilitate the tourism planning, and presents a method to evaluate the carrying capacity. The method called matter element analysis can solve the uncertain and incompatible problem of the evaluated factors in assessing carrying capacity.The current state of a destination's carrying capacity can be determined by establishing the standard indexes and the matter element model. Through the evaluating of the travel industry zones of the Autonomous Prefecture of Western Hunan, the method is proved to be simple and feasible, and it is improved to be significant for the tourism planning and determination as well as the sustainable development of the regional tourism.

  10. Determination of the sediment carrying capacity based on perturbed theory.

    Science.gov (United States)

    Ni, Zhi-hui; Zeng, Qiang; Li-chun, Wu

    2014-01-01

    According to the previous studies of sediment carrying capacity, a new method of sediment carrying capacity on perturbed theory was proposed. By taking into account the average water depth, average flow velocity, settling velocity, and other influencing factors and introducing the median grain size as one main influencing factor in deriving the new formula, we established a new sediment carrying capacity formula. The coefficients were determined by the principle of dimensional analysis, multiple linear regression method, and the least square method. After that, the new formula was verified through measuring data of natural rivers and flume tests and comparing the verified results calculated by Cao Formula, Zhang Formula, Li Formula, Engelung-Hansen Formula, Ackers-White Formula, and Yang Formula. According to the compared results, it can be seen that the new method is of high accuracy. It could be a useful reference for the determination of sediment carrying capacity.

  11. Measuring the Magnetic Force on a Current-Carrying Conductor.

    Science.gov (United States)

    Herreman, W.; Huysentruyt, R.

    1995-01-01

    Describes a fast and simple method for measuring the magnetic force acting on a current-carrying conductor using a digital balance. Discusses the influence of current intensity and wire length on the magnetic force on the conductor. (JRH)

  12. The logistic model-generated carrying capacities for wild herbivores ...

    African Journals Online (AJOL)

    Jesse

    Modelled as discrete-time logistic equations with fixed carrying capacities, it captures the wildlife herbivore population dynamics. Time series data, covering a period ..... Building Models for Conservation and. Wildlife Management. (New York ...

  13. Langkawi Island, Social Aspect and the Carrying Capacity

    OpenAIRE

    Mohamad Diana; Jaafar Mastura; Marzuki Azizan

    2014-01-01

    The aptitude to convince a range of preferences has facilitated the island tourism attractions to achieve international recognition and at present KILIM Geopark is enjoyed by a prominent percentage of individuals wide-reaching. Conventional knowledge has that the island attractions are operating on the limited immobile resources, of which, have raised the scholars’ concerns over the carrying capacity issue. When analyzing carrying capacity, scholars have traditionally focused on the environme...

  14. The Construction of Social Darwinism in Sister Carrie

    Institute of Scientific and Technical Information of China (English)

    薛晶晶; 秦素华

    2014-01-01

    Social Darwinism is an important theory reflected in Sister Carrie. This thesis is to interpret the characters’fates with Social Darwinism.“Survival of the fittest”is an important theme. Carrie is the winner of life and Hurtwood is the loser. Their adjustability to the environment determines their future. It is hoped to help the readers construct a better understanding on this theory.

  15. Design and Implementation of High Speed Carry Select Adder

    OpenAIRE

    B. Gopinath; N Sangeetha; S.Jenifer nancy; T.Umarani

    2015-01-01

    In electronic adder is a digital circuit that performs addition of numbers. Adders can be constructed for many numerical representations such as arithmetic and logical operation. The most adders operates on binary numbers. Among the different types of adders, carry select adder is a one of the fastest adder.The gate level modification is to reduce the power and area of carry select adder by using the concept of Arithmetic Logic Unit (ALU). In this paper , different techniques such as Binary T...

  16. Missile captive carry monitoring using a capacitive MEMS accelerometer

    Science.gov (United States)

    Hatchell, Brian; Mauss, Fred; Santiago-Rojas, Emiliano; Amaya, Ivan; Skorpik, Jim; Silvers, Kurt; Marotta, Steve

    2010-03-01

    Military missiles are exposed to many sources of mechanical vibration that can affect system reliability, safety, and mission effectiveness. One of the most significant exposures to vibration occurs when the missile is being carried by an aviation platform, which is a condition known as captive carry. If the duration of captive carry exposure could be recorded during the missile's service life, several advantages could be realized. Missiles that have been exposed to durations outside the design envelop could be flagged or screened for maintenance or inspection; lightly exposed missiles could be selected for critical mission applications; and missile allocation to missions could be based on prior use to avoid overuse. The U. S. Army Aviation and Missile Research Development and Engineering Center (AMRDEC) has been developing health monitoring systems to assess and improve reliability of missiles during storage and field exposures. Under the direction of AMRDEC staff, engineers at the Pacific Northwest National Laboratory have developed a Captive Carry Health Monitor (CCHM) for the HELLFIRE II missile. The CCHM is an embedded usage monitoring device installed on the outer skin of the HELLFIRE II missile to record the cumulative hours the host missile has been in captive carry mode and thereby assess the overall health of the missile. This paper provides an overview of the CCHM electrical and package design, describes field testing and data analysis techniques used to identify captive carry, and discusses the potential application of missile health and usage data for real-time reliability analysis and fleet management.

  17. Missile Captive Carry Monitoring using a Capacitive MEMS Accelerometer

    Energy Technology Data Exchange (ETDEWEB)

    Hatchell, Brian K.; Mauss, Fredrick J.; Santiago-Rojas, Emiliano; Amaya, Ivan A.; Skorpik, James R.; Silvers, Kurt L.; Marotta, Steve

    2010-04-08

    Military missiles are exposed to many sources of mechanical vibration that can affect system reliability, safety, and mission effectiveness. One of the most significant exposures to vibration occurs when the missile is being carried by an aviation platform, which is a condition known as captive carry. If the duration of captive carry exposure could be recorded during the missile’s service life, several advantages could be realized. Missiles that have been exposed to durations outside the design envelop could be flagged or screened for maintenance or inspection; lightly exposed missiles could be selected for critical mission applications; and missile allocation to missions could be based on prior use to avoid overuse. The U. S. Army Aviation and Missile Research Development and Engineering Center (AMRDEC) has been developing health monitoring systems to assess and improve reliability of missiles during storage and field exposures. Under the direction of AMRDEC staff, engineers at the Pacific Northwest National Laboratory have developed a Captive Carry Health Monitor (CCHM) for the HELLFIRE II missile. The CCHM is an embedded usage monitoring device installed on the outer skin of the HELLFIRE II missile to record the cumulative hours the host missile has been in captive carry mode and thereby assess the overall health of the missile. This paper provides an overview of the CCHM electrical and package design, describes field testing and data analysis techniques used to identify captive carry, and discusses the potential application of missile health and usage data for real-time reliability analysis and fleet management.

  18. Carrying capacity: the tradition and policy implications of limits

    Directory of Open Access Journals (Sweden)

    Virginia Deane Abernethy

    2001-01-01

    Full Text Available ABSTRACT: Within just the last few centuries, science and technology have enlarged human capabilities and population size until humans now take, for their own use, nearly half of the Earth's net terrestrial primary production. An ethical perspective suggests that potentials to alter, or further increase, humanity's use of global resources should be scrutinized through the lenses of self-interested foresightedness and respect for non-human life. Without overtly invoking ethics, studies of the carrying capacity achieve just this objective. Carrying capacity is an ecological concept that expresses the relationship between a population and the natural environment on which it depends for ongoing sustenance. Carrying capacity assumes limits on the number of individuals that can be supported at a given level of consumption without degrading the environment and, therefore, reducing future carrying capacity. That is, carrying capacity addresses long-term sustainability. Worldviews differ in the importance accorded to the carrying capacity concept. This paper addresses three worldviews - ecological, romantic, and entrepreneurial - and explores the ethics and the policy implications of their contrasting perspectives.

  19. Locomotion while load-carrying in reduced gravities.

    Science.gov (United States)

    Wickman, L A; Luna, B

    1996-10-01

    Supporting the mass of a protective suit and portable life support system (PLSS) will impose an energy requirement on planetary astronauts. To design extravehicular protective equipment for planetary missions, scientists must learn more about human physical capabilities while load-carrying in reduced gravities. In this study, an underwater treadmill and weighting system were used to simulate reduced-gravity locomotion while load-carrying. The test matrix included 3 gravity levels, 6 subjects, 2 locomotion speeds, and a range of load sizes. Energy expenditure, calculated from measured oxygen consumption, is positively correlated with gravity level, speed, and load size. The data are used to project that individuals in average physical condition will be able to walk for 8 h on the Moon while carrying up to 170% of their body mass without undue fatigue, and on Mars with up to 50% of their body mass. These approximate limits, especially for Martian gravity, may prove quite a challenge for designers of advanced protective systems. Requirements for regenerable and non-venting PLSS components have been driving the total projected masses of advanced PLSSs increasingly higher, perhaps beyond what is reasonable to carry. However, the larger mass can be beneficial in maintaining bone mass. Using Whalen's model (1988), the daily planetary walking times required to maintain bone mass were calculated for a range of carried load sizes. The calculated times were unattainably high, suggesting that some combination of loads carrying and supplemental bone maintenance measures will likely be required to maintain bone mass in reduced gravity environments.

  20. The Broken American Dream Based on Sister Carrie

    Institute of Scientific and Technical Information of China (English)

    Dong Wenjuan

    2012-01-01

      Sister Carrie is the first work of Theodore Dreiser, It tells us how a country maiden becomes a famous star in Broadway. In the novel, Dreiser describes the living conditions and emotion changes of Carrie very vividly. Sister Carrie takes true realism as its distinctive feature, reflects the tragic fact that people pursue American dream fanatically in the early twentieth century. This paper exposes the theme of instinct, which drives people to enjoy but disillusion finally, and illustrates that it is impossible to possess true happiness in a money-oriented capitalism society%  Sister Carrie is the first work of Theodore Dreiser, Ittells us how a country maiden becomes a famous star in Broadway.In the novel, Dreiser describes the living conditions and emotion changes of Carrie very vividly. Sister Carrie takes true realism as itsdistinctive feature, reflects the tragic fact that people pursue Americandream fanatically in the early twentieth century. This paper exposes the theme of instinct, which drives people to enjoy but disillusion finally, and illustrates that it is impossible to possess true happiness in a money-oriented capitalism society

  1. Integrated Coastal Zone Planning Based on Environment Carrying Capacity Analysis

    Science.gov (United States)

    Miharja, M.; Arsallia, S.

    2017-07-01

    Coastal zone is a crucial area in terms of planning development. It holds high economic value, which affect to increasing number of inhabitants living in the area. As a result, this condition influences environmental degradation. Thus, in every attempt towards coastal zone development, it is crucial to always refer to environment carrying capacity. Carrying capacity is the limit of a certain coastal zone capability to support all human created activities, in which all ecological performances are maintained at sustainable level. The failure to establish strong and clear method and regulation on carrying capacity analysis will lead to a very risky coastal zone development, which in turn would threat the area’s sustainability. This paper discusses method for analysing carrying capacity of coastal zone as important input for the area development plan. Two key parameters, i.e. land and clean water carrying capacities are discussed to form carrying capacity analytical method. Furthermore, an empirical data of Ambon Bay, Moluccas Province, is used to illustrate the operationalization of the method.

  2. Reducing weapon-carrying among urban American Indian young people.

    Science.gov (United States)

    Bearinger, Linda H; Pettingell, Sandra L; Resnick, Michael D; Potthoff, Sandra J

    2010-07-01

    To examine the likelihood of weapon-carrying among urban American Indian young people, given the presence of salient risk and protective factors. The study used data from a confidential, self-report Urban Indian Youth Health Survey with 200 forced-choice items examining risk and protective factors and social, contextual, and demographic information. Between 1995 and 1998, 569 American Indian youths, aged 9-15 years, completed surveys administered in public schools and an after-school program. Using logistic regression, probability profiles compared the likelihood of weapon-carrying, given the combinations of salient risk and protective factors. In the final models, weapon-carrying was associated significantly with one risk factor (substance use) and two protective factors (school connectedness, perceiving peers as having prosocial behavior attitudes/norms). With one risk factor and two protective factors, in various combinations in the models, the likelihood of weapon carrying ranged from 4% (with two protective factors and no risk factor in the model) to 80% of youth (with the risk factor and no protective factors in the model). Even in the presence of the risk factor, the two protective factors decreased the likelihood of weapon-carrying to 25%. This analysis highlights the importance of protective factors in comprehensive assessments and interventions for vulnerable youth. In that the risk factor and two protective factors significantly related to weapon-carrying are amenable to intervention at both individual and population-focused levels, study findings offer a guide for prioritizing strategies for decreasing weapon-carrying among urban American Indian young people. Copyright (c) 2010 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

  3. Bullying and weapon carrying: a meta-analysis.

    Science.gov (United States)

    van Geel, Mitch; Vedder, Paul; Tanilon, Jenny

    2014-08-01

    Studies suggest that adolescents involved in bullying are more likely to carry weapons than their uninvolved peers. To use meta-analyses to determine whether victims, bullies, and bully-victims are more likely to carry weapons than uninvolved peers. PsycINFO, ERIC, MEDLINE, LILACS, EMBASE, and Dissertation Abstracts International were searched for relevant publications (1950 through January 2014). The reference list of a review article and reference lists of retrieved articles were checked for further relevant studies. Studies were included if they provided an effect size comparing the weapon carrying of adolescent victims, bullies, or bully-victims with that of uninvolved peers. Studies that included individuals older than 21 years were excluded, as were studies that focused on incarcerated youth or youth diagnosed as having a psychopathologic condition. Studies were coded independently by 2 of us. The agreement rate was 93%. Effect sizes were coded that compared victims, bullies, or bully-victims with uninvolved peers. Meta-analyses were based on 22 studies for victims (n = 257 179), 15 studies for bullies (n = 236 145), and 8 studies for bully-victims (n = 199 563). This study focused on weapon carrying among adolescents. Hypotheses were formulated before the study. Victims (odds ratio, 1.97; 95% CI, 1.62-2.39), bullies (3.25; 2.72-3.89), and bully-victims (4.95; 3.77-6.50) were more likely to carry weapons than uninvolved peers. Analyses provided no indication of publication bias. Studies conducted in the United States found stronger relations between being a bully-victim and weapon carrying (odds ratio, 7.84; 95% CI, 6.02-10.21) than studies from other countries (3.62; 2.30-5.68; Q1 = 8.401; P = .004). Involvement in bullying as a victim, bully, or bully-victim is related to weapon carrying.

  4. Model Modification and Application on Carrying Capacity of Relative Resources

    Institute of Scientific and Technical Information of China (English)

    Li Zehong; Dong Suocheng; Gao Dan

    2009-01-01

    Based on the retrospection of researches on carry-ing capacity, this article reviewed systematically the research progresses on carrying capacity of relative resources (CCRR).Then the viewpoint was put forward that CCRR is not an ap-propriate method of appraising the regional sustainability, but a sound way to obtain cognition for coordinating spatial loca-tion and flow of population and economy.However, as the most popular computing method of CCRR, the Weighting Linear Sum Model is defective in the random of weight choice and the neglect of matching among different resources.Therefore, this article established the Geometric Model on CCRR based on modifying Weighting Linear Sum Model, which can be used to appraise regions where resources are close matching.Em-ploying the Geometric Model, the article empirically analyzed the population and economic CCRR in Hubei Province from 1978 to 2006.The result indicates that the population in Hubei Province is overloading while the economic carrying capacity is abundant compared to the whole country, and the economic insufficiency restricts the population carrying capacity.In the future, Hubei Province will become one of the core developing zones which are characterized by economic conglomeration.

  5. Boundary slippage for generating hydrodynamic load-carrying capacity

    Institute of Scientific and Technical Information of China (English)

    ZHANG Yong-bin

    2008-01-01

    Boundary slippage is used to generate the load-carrying capacity of the hydrodynamic contact between two parallel plane surfaces.In the fluid inlet zone,the fluidcontact interfacial shear strength on a stationary surface is set at low to generate boundary slippage there,while in the fluid outlet zone the fluid-contact interfacial shear strength on the stationary surface is set at high enough to prevent the occurrence of boundary slippage.The fluid-contact interfacial shear strength on the entire moving surface is set at high enough to prevent boundary slippage on the moving surface.These hydrodynamic contact configurations are analyzed to generate the pronounced load-carrying capacity.The optimum ratio of the outlet zone width to the inlet zone width for the maximum load-carrying capacity of the whole contact is found to be 0.5.

  6. Hierarchical population model with a carrying capacity distribution

    CERN Document Server

    Indekeu, J O

    2002-01-01

    A time- and space-discrete model for the growth of a rapidly saturating local biological population $N(x,t)$ is derived from a hierarchical random deposition process previously studied in statistical physics. Two biologically relevant parameters, the probabilities of birth, $B$, and of death, $D$, determine the carrying capacity $K$. Due to the randomness the population depends strongly on position, $x$, and there is a distribution of carrying capacities, $\\Pi (K)$. This distribution has self-similar character owing to the imposed hierarchy. The most probable carrying capacity and its probability are studied as a function of $B$ and $D$. The effective growth rate decreases with time, roughly as in a Verhulst process. The model is possibly applicable, for example, to bacteria forming a "towering pillar" biofilm. The bacteria divide on randomly distributed nutrient-rich regions and are exposed to random local bactericidal agent (antibiotic spray). A gradual overall temperature change away from optimal growth co...

  7. A case study on non-point source pollution and environmental carrying capacity of animal raising industry in subtropical watershed%亚热带流域氮磷排放与养殖业环境承载力实例研究

    Institute of Scientific and Technical Information of China (English)

    孟岑; 李裕元; 许晓光; 高茹; 王毅; 张满意; 吴金水

    2013-01-01

    畜禽养殖业粪便排放已经成为我国农村地区主要的农业面源污染源之一,也是制约养殖业良性发展的主要瓶颈.本文以湖南省长沙县典型亚热带流域为研究单元,基于流域水环境定位观测、耕地氮(N)磷(P)消纳能力以及养殖业调查和土壤分析资料,初步分析了亚热带丘陵区的面源污染现状及畜禽养殖业的环境承载力.结果表明,研究区金井河流域134.4 km2范围内N、P年负荷分别为N 2.72 t·km-2和P0.11t·km-2,其中养殖粪便对水体总氮(TN)、总磷(TP)负荷的贡献率分别约为42.2%和62.0%.区内平均畜禽养殖密度为3.46 AU·hm-2(相当于流域内年出栏生猪24.39万头),显著高于现有化肥用量条件下流域的实际承载力1.13 AU·hm-2(相当于流域内年出栏生猪6.35万头),因此养殖密度过高是导致研究区水体NP负荷较高的主要原因.区内N、P盈余量分别为N 35.8 kg·hm-2、P 18.61 kg·hm-2.研究区基本不施用化肥条件下畜禽养殖业的最大环境承载力为7.26 AU·hm-2,在有机肥占合理施肥量30%条件下,当地畜禽养殖业的环境承载力为2.74AU·hm-2(相当于流域内年出栏生猪19.50万头).降低养殖密度、调整养殖业空间布局以及提高养殖废弃物的资源化利用率是防治当前面源污染的有效途径.%The discharge of faeces from animal production is a major source of nitrogen ( N) and phosphorus (P) pollutants in the subtropical region of China. To quantify the N and F load from animal production to hydro-systems in the region, surveys on pig density and N,P inputs to farmlands, soil N and P contents, and annual observations of the N and P flows in the streams and the terminal river were carried out in a hilly watershed (134.4 km2 ) in Changsha County, Hunan Province. It was showed that the total NP loads from the watershed to the terminal river was 2.72 t and 0. 11 t·km-2·a-1, respectively ; within which 42. 2% of the N and 62. 0% of

  8. Evaluation of carrying capacity and territorial environmental sustainability

    Directory of Open Access Journals (Sweden)

    Giuseppe Ruggiero

    2012-09-01

    Full Text Available Land use has a great impact on environmental quality, use of resources, state of ecosystems and socio-economic development. Land use can be considered sustainable if the environmental pressures of human activities do not exceed the ecological carrying capacity. A scientific knowledge of the capability of ecosystems to provide resources and absorb waste is a useful and innovative means of supporting territorial planning. This study examines the area of the Province of Bari to estimate the ecosystems’ carrying capacity, and compare it with the current environmental pressures exerted by human activities. The adapted methodology identified the environmentally sustainable level for one province.

  9. Design and Analysis of a High Speed Carry Select Adder

    OpenAIRE

    Simarpreet Singh Chawla; Swapnil Aggarwal; Anshika; Nidhi Goel

    2015-01-01

    An optimal high-speed and low-power VLSI architecture requires an efficient arithmetic processing unit that is optimized for speed and power consumption. Adders are one of the widely used in digital integrated circuit and system design.High speed adder is the necessary component in a data path, e.g. Microprocessors and a Digital signal processor. The present paper proposes a novel high-speed adder by combining the advantages of Carry Look Ahead Adder (CLAA) and Carry Select Adder (CSA), devis...

  10. Design and Analysis of a High Speed Carry Select Adder

    OpenAIRE

    Simarpreet Singh Chawla; Swapnil Aggarwal; Anshika; Nidhi Goel

    2015-01-01

    An optimal high-speed and low-power VLSI architecture requires an efficient arithmetic processing unit that is optimized for speed and power consumption. Adders are one of the widely used in digital integrated circuit and system design. High speed adder is the necessary component in a data path, e.g. Microprocessors and a Digital signal processor. The present paper proposes a novel high-speed adder by combining the advantages of Carry Look Ahead Adder (CLAA) and Carry Select Adder (CSA), devi...

  11. Description of Model Tests Carried Out by Aalborg University

    DEFF Research Database (Denmark)

    Frigaard, Peter; Schlütter, F.; Andersen, H.

    1996-01-01

    As associated partner, Aalborg University (AU) have participated in different aspects of "the Zeebrugge project". AU has carried out an extensive number of small-scale model tests (1:65) with the Zeebrugge breakwater with the aim of investigating scale-effects.......As associated partner, Aalborg University (AU) have participated in different aspects of "the Zeebrugge project". AU has carried out an extensive number of small-scale model tests (1:65) with the Zeebrugge breakwater with the aim of investigating scale-effects....

  12. Truncated prelamin A expression in HGPS-like patients: a transcriptional study

    NARCIS (Netherlands)

    Barthelemy, F.; Navarro, C; Fayek, R.; Silva, N.; Roll, P.; Sigaudy, S.; Oshima, J.; Bonne, G.; Papadopoulou-Legbelou, K.; Evangeliou, A.E.; Spilioti, M.; Lemerrer, M.; Wevers, R.A.; Morava, E.; Robaglia-Schlupp, A.; Levy, N.; Bartoli, M.; Sandre-Giovannoli, A. De

    2015-01-01

    Premature aging syndromes are rare genetic disorders mimicking clinical and molecular features of aging. A recently identified group of premature aging syndromes is linked to mutation of the LMNA gene encoding lamins A and C, and is associated with nuclear deformation and dysfunction. Hutchinson-Gil

  13. Truncated prelamin A expression in HGPS-like patients: a transcriptional study

    NARCIS (Netherlands)

    Barthelemy, F.; Navarro, C; Fayek, R.; Silva, N.; Roll, P.; Sigaudy, S.; Oshima, J.; Bonne, G.; Papadopoulou-Legbelou, K.; Evangeliou, A.E.; Spilioti, M.; Lemerrer, M.; Wevers, R.A.; Morava, E.; Robaglia-Schlupp, A.; Levy, N.; Bartoli, M.; Sandre-Giovannoli, A. De

    2015-01-01

    Premature aging syndromes are rare genetic disorders mimicking clinical and molecular features of aging. A recently identified group of premature aging syndromes is linked to mutation of the LMNA gene encoding lamins A and C, and is associated with nuclear deformation and dysfunction. Hutchinson-Gil

  14. An Alternative Approach for High Speed Railway Carrying Capacity Calculation Based on Multiagent Simulation

    Directory of Open Access Journals (Sweden)

    Mo Gao

    2016-01-01

    Full Text Available It is a multiobjective mixed integer programming problem that calculates the carrying capacity of high speed railway based on mathematical programming method. The model is complex and difficult to solve, and it is difficult to comprehensively consider the various influencing factors on the train operation. The multiagent theory is employed to calculate high speed railway carrying capacity. In accordance with real operations of high speed railway, a three-layer agent model is developed to simulate the operating process of high speed railway. In the proposed model, railway network agent, line agent, station agent, and train agent are designed, respectively. To validate the proposed model, a case study is performed for Beijing–Shanghai high speed railway by using NetLogo software. The results are consistent with the actual data, which implies that the proposed multiagent method is feasible to calculate the carrying capacity of high speed railway.

  15. Ticks Carrying Lyme Disease Confirmed in Eastern National Parks

    Science.gov (United States)

    ... html Ticks Carrying Lyme Disease Confirmed in Eastern National Parks U.S. National Park Service and CDC advise using insect repellents on ... Planning a hiking trip in an eastern U.S. national park? Better pack tick repellent -- a new study found ...

  16. 44 CFR 332.3 - Carrying out voluntary agreements.

    Science.gov (United States)

    2010-10-01

    ... advance, each meeting of the participants in the agreement held to discuss problems, determine policies... § 332.5 of this part. A person attending a meeting under this section may present oral or written data... communications among themselves or with any other member of their industry, related to the carrying out of...

  17. El naturalismo americano: Theodore Dreiser y Sister Carrie

    Directory of Open Access Journals (Sweden)

    Dolores G. ALONSO MULAS

    2009-08-01

    Full Text Available Para situar a un escritor, como Theodore Dreiser, y especialmente su novela Sister Carrie dentro de un movimiento literario y de una etapa determinada de la historia americana, es necesario dar un breve repaso al naturalismo, llegado a América a través de Stephen Crane

  18. Carrying Out Collaborative Action Research in a Practicum

    Science.gov (United States)

    Ho, Belinda

    2013-01-01

    To help in-service English teachers improve their teaching practices and pupils' learning opportunities through an enquiry-oriented and cooperative approach, the author carried out collaborative action research during a practicum in a teacher education course at a university in Hong Kong. This article describes how the collaborative research…

  19. Arrangement for carrying out and studying chemical reactions

    NARCIS (Netherlands)

    Langeveld, A.D.; Makkee, M.; Moulijn, J.A.

    1993-01-01

    Abstract of NL 9102029 (A) Described is an arrangement for carrying out TAP experiments. Such an arrangement comprises a reaction chamber in which a very short-lived beam of molecules is directed at a target to produce a short-lived beam of intermediate-product molecules, and a vacuum chamber wher

  20. Victimization and Health Risk Factors among Weapon-Carrying Youth

    Science.gov (United States)

    Stayton, Catherine; McVeigh, Katharine H.; Olson, E. Carolyn; Perkins, Krystal; Kerker, Bonnie D.

    2011-01-01

    Objective: To compare health risks of 2 subgroups of weapon carriers: victimized and nonvictimized youth. Methods: 2003-2007 NYC Youth Risk Behavior Surveys were analyzed using bivariate analyses and multinomial logistic regression. Results: Among NYC teens, 7.5% reported weapon carrying without victimization; 6.9% reported it with victimization.…

  1. Ferromagnetic behavior of formyl-group-carrying stable thioaminyl radicals.

    Science.gov (United States)

    Miura, Yozo; Nakamura, Shogo; Teki, Yoshio

    2003-10-17

    Four formyl-group-carrying thioaminyl radicals were generated, and one radical could be isolated as radical crystals. Magnetic susceptibility measurements of the isolated radical showed a ferromagnetic regular linear-chain interaction of 2J/k(B) = 3.2 K, which was explained in terms of the X-ray crystallographic results.

  2. Debris-carrying camouflage among diverse lineages of Cretaceous insects

    Science.gov (United States)

    Wang, Bo; Xia, Fangyuan; Engel, Michael S.; Perrichot, Vincent; Shi, Gongle; Zhang, Haichun; Chen, Jun; Jarzembowski, Edmund A.; Wappler, Torsten; Rust, Jes

    2016-01-01

    Insects have evolved diverse methods of camouflage that have played an important role in their evolutionary success. Debris-carrying, a behavior of actively harvesting and carrying exogenous materials, is among the most fascinating and complex behaviors because it requires not only an ability to recognize, collect, and carry materials but also evolutionary adaptations in related morphological characteristics. However, the fossil record of such behavior is extremely scarce, and only a single Mesozoic example from Spanish amber has been recorded; therefore, little is known about the early evolution of this complicated behavior and its underlying anatomy. We report a diverse insect assemblage of exceptionally preserved debris carriers from Cretaceous Burmese, French, and Lebanese ambers, including the earliest known chrysopoid larvae (green lacewings), myrmeleontoid larvae (split-footed lacewings and owlflies), and reduviids (assassin bugs). These ancient insects used a variety of debris material, including insect exoskeletons, sand grains, soil dust, leaf trichomes of gleicheniacean ferns, wood fibers, and other vegetal debris. They convergently evolved their debris-carrying behavior through multiple pathways, which expressed a high degree of evolutionary plasticity. We demonstrate that the behavioral repertoire, which is associated with considerable morphological adaptations, was already widespread among insects by at least the Mid-Cretaceous. Together with the previously known Spanish specimen, these fossils are the oldest direct evidence of camouflaging behavior in the fossil record. Our findings provide a novel insight into early evolution of camouflage in insects and ancient ecological associations among plants and insects. PMID:27386568

  3. Cultural Carrying Capacity: A Biological Approach to Human Problems.

    Science.gov (United States)

    Hardin, Garrett

    1992-01-01

    In discussing the human and cultural implications of scientific discoveries and knowledge, the biological concept of carrying capacity is explored. Maintaining that human beings are truly animals answering to principles that govern all animals, the author addresses the need for human populations to work within the context of culture and carrying…

  4. Cognitive Load in Voice Therapy Carry-Over Exercises

    Science.gov (United States)

    Iwarsson, Jenny; Morris, David Jackson; Balling, Laura Winther

    2017-01-01

    Purpose: The cognitive load generated by online speech production may vary with the nature of the speech task. This article examines 3 speech tasks used in voice therapy carry-over exercises, in which a patient is required to adopt and automatize new voice behaviors, ultimately in daily spontaneous communication. Method: Twelve subjects produced…

  5. Wakes in Dilatonic Current-Carrying Cosmic Strings

    CERN Document Server

    Oliveira, A L N

    2003-01-01

    In this work, we present the gravitational field generated by a cosmic string carrying a timelike current in the scalar-tensor gravities. The mechanism of formation and evolution of wakes is fully investigated in this framework. We show that the inclusion of electromagnetic properties for the string induces logarithmic divergences in the accretion problem.

  6. Nanoparticles carry chemotherapy drug deeper into solid tumors

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    @@ CAS researchers have developed a new drug delivery method using nano-sized molecules to carry the chemotherapy drug doxorubicin to tumors, improving the effectiveness of the drug in mice and increasing their survival time. Their work has been reported online June 26 in the Journal of the National Cancer Institute.

  7. Maze Busters: Carrie Miyoshi Macfarlane & Kathleen Sheehan--Harvard University

    Science.gov (United States)

    Library Journal, 2004

    2004-01-01

    Even if one is equipped with an MLS, the 11 libraries that comprise the Harvard College Library can be pretty daunting. That is why Carrie Miyoshi Macfarlane and Kathleen Sheehan created Threading the Maze. The online publication is presented to students in expository writing, the one course all undergraduates must take. "This highly effective…

  8. Connection and Commitment: The Career of Carrie Billy

    Science.gov (United States)

    Peterson, Richard

    2015-01-01

    Carrie Billy, a member of the Navajo Nation and CEO and president of the American Indian Higher Education Consortium (AIHEC), attributes one of the country's oldest youth organizations, Girl Scouts, for opening her mind to the possibility of creating change for countless citizens. She is a trained attorney and has made it her life work to advocate…

  9. "The Bell Curve" and Carrie Buck: Eugenics Revisited.

    Science.gov (United States)

    Smith, J. David

    1995-01-01

    The 1994 publication of "The Bell Curve" by R. Herrnstein and C. Murray is compared to other examples of eugenic principles, including the sterilization of "feebleminded" Carrie Buck, family degeneracy studies focusing on lower class Caucasian families, and other works that view the poorest and least educated members of society…

  10. Pyrosequencing reveals bacteria carried in different wind eroded sediments

    Science.gov (United States)

    Little is known about the microbial communities carried in wind-eroded sediments from various soil types and land management systems. A novel technique, pyrosequencing, promises to expand our understanding of the vast microbial diversity of soils and eroded sediments as it can sequence between 10-10...

  11. Efficient Design of Ripple Carry Adder and Carry Skip Adder with Low Quantum Cost and Low Power Consumption

    Directory of Open Access Journals (Sweden)

    Nidhi

    2014-07-01

    Full Text Available The addition of two binary numbers is the important and most frequently used arithmetic process on microprocessors, digital signal processors (DSP, and data-processing application-specific integrated circuits (ASIC. Therefore, binary adders are critical structure blocks in very large-scale integrated (VLSI circuits. Their effective application is not trivial because a costly carry spread operation involving all operand bits has to be achieved. Many different circuit constructions for binary addition have been planned over the last decades, covering a wide range of presentation characteristics. In today era, reversibility has become essential part of digital world to make digital circuits more efficient. In this paper, we have proposed a new method to reduce quantum cost for ripple carry adder and carry skip adder. The results are simulated in Xilinx by using VHDL language.

  12. Variable Block Carry Skip Logic using Reversible Gates

    CERN Document Server

    Islam, Md Rafiqul; Karim, Muhammad Rezaul; Mahmud, Abdullah Al; Babu, Hafiz Md Hasan

    2010-01-01

    Reversible circuits have applications in digital signal processing, computer graphics, quantum computation and cryptography. In this paper, a generalized k*k reversible gate family is proposed and a 3*3 gate of the family is discussed. Inverter, AND, OR, NAND, NOR, and EXOR gates can be realized by this gate. Implementation of a full-adder circuit using two such 3*3 gates is given. This full-adder circuit contains only two reversible gates and produces no extra garbage outputs. The proposed full-adder circuit is efficient in terms of gate count, garbage outputs and quantum cost. A 4-bit carry skip adder is designed using this full-adder circuit and a variable block carry skip adder is discussed. Necessary equations required to evaluate these adder are presented.

  13. High Speed Boosted Cmos Differential Logic for Ripple Carry Adders

    Directory of Open Access Journals (Sweden)

    Meenu Roy,

    2014-01-01

    Full Text Available This paper describes a high speed boosted CMOS differential logic which is applicable in Ripple Carry Adders. The proposed logic operating with supply voltage approaching the MOS threshold voltage. The logic style improves switching speed by boosting the gate-source voltage of transistors along timing critical signal path. It allows a single boosting circuit to be shared by complementary outputs as a result the area overhead also minimizes. As compared to the conventional logic gates the EDP (energy delay product is improved. The test sets of logic gates and adders where designed in tsmc0.18μm of Mentor Graphics EDA tool. The experimental result for Ripple Carry Adders using the proposed logic style revealed that the addition time is reduced as compared with the conventional CMOS circuits.

  14. A novel reversible carry-selected adder with low latency

    Science.gov (United States)

    Li, Ming-Cui; Zhou, Ri-Gui

    2016-07-01

    Reversible logic is getting more and more attention in quantum computing, optical computing, nanotechnology and low-power complementary metal oxide semiconductor designs since reversible circuits do not loose information during computation and have only small energy dissipation. In this paper, a novel carry-selected reversible adder is proposed primarily optimised for low latency. A 4-bit reversible full adder with two kinds of outputs, minimum delay and optimal quantum cost is presented as the building block for ?-bit reversible adder. Three new reversible gates NPG (new Peres gate), TEPG (triple extension of Peres gate) and RMUX21 (reversible 2-to-1 multiplexer) are proposed and utilised to design efficient adder units. The secondary carry propagation chain is carefully designed to reduce the time consumption. The novelty of the proposed design is the consideration of low latency. The comparative study shows that the proposed adder achieves the improvement from 61.46% to 95.29% in delay over the existing designs.

  15. Carrying guns in public: legal and public health implications.

    Science.gov (United States)

    Vernick, Jon S

    2013-03-01

    In District of Columbia v. Heller, the U.S. Supreme Court ruled that the Second Amendment protects an individual's right to own handguns in the home for protection, invalidating a Washington, D.C. law banning most handgun possession. The Heller decision, however, provided lower courts with little guidance regarding how to judge the constitutionality of gun laws other than handgun bans. Nevertheless, lower courts have upheld the vast majority of federal, state, and local gun laws challenged since Heller. One area in which some lower courts have disagreed has been the constitutionality of laws regulating the ability to carry firearms in public. This issue may be the next to be addressed by the Supreme Court under its evolving Second Amendment jurisprudence. Courts should carefully consider the negative public health and safety implications of gun carrying in public as they weigh the constitutionality of these laws.

  16. A C-Testable Multiple-Block Carry Select Adder

    Science.gov (United States)

    Kito, Nobutaka; Fujii, Shinichi; Takagi, Naofumi

    We propose a C-testable multiple-block carry select adder with respect to the cell fault model. Full adders and 2: 1 multiplexers are considered as cells. By an additional external input, we obtain a C-testable carry select adder. We only modify the least significant position of each block. The adder is testable with a test set consisting of 16 patterns regardless of the size of each block and the number of blocks. This is the minimum test set for the adder. We show two gate-level implementations of the adder which are testable with a test set of 9 patterns and 7 patterns respectively, with respect to the single stuck-at fault model.

  17. Different Ways of Carrying Bags in Mental Retarded Students

    Directory of Open Access Journals (Sweden)

    Saideh-Sadat Mortazavi

    2012-10-01

    Full Text Available School as an educational and social center is linked with various aspects of child’s growth. The impact of objects, tools, and lifestyle on the development of human performance is not hidden from anyone [1].Tasell Lauri, the head of Cairo Praktive in Australia, in a paper warned parents about bags as a tool that students carry every day, and he is believes that many spinal disorders in adults is caused by childhood trauma. Studies on children and patients with special needs and such as myelomenangocele, cerebral palsy, and neurofibromatosis precisely show abnormal growth of spinal disorders, muscle imbalance, wrong posture [2]. Carrying stationery in an inappropriate tool can cause irreversible effects.

  18. Superpositions of light fields carrying orbital angular momentum

    CSIR Research Space (South Africa)

    Dudley, Angela L

    2012-01-01

    Full Text Available OF LIGHT FIELDS CARRYING ORBITAL ANGULAR MOMENTUM By Angela Dudley A thesis submitted in fulfilment of the academic requirements for the PhD degree of Science in the School of Chemistry and Physics, University of KwaZulu-Natal, Durban... this dissertation for submission. _________________________________ Prof Andrew Forbes On this_______day of____________________________2012 iv Declaration 2 - Plagiarism I, ???????????????. declare that 1...

  19. Modeling the Flexural Carrying Capacity of Corroded RC Beam

    Institute of Scientific and Technical Information of China (English)

    WANG Xiao-hui; LIU Xi-la

    2008-01-01

    Considering the change of bond strength between corroded steel and concrete, flexural carrying ca-pacity of corroded reinforced concrete (RC) beam was calculated. On the basis of the condition of equilibriumof forces and compatibility of deformations for the whole beam, a model for the prediction of flexural carryingcapacity of the corroded RC beam was proposed. Comparison of the model's predictions with the experimentalresults published in the literature shows the practicality of the proposed method.

  20. The calming effect of maternal carrying in different mammalian species

    Directory of Open Access Journals (Sweden)

    Gianluca eEsposito

    2015-04-01

    Full Text Available Attachment theory postulates that mothers and their infants possess some basic physiological mechanisms that favour their dyadic interaction and bonding. Many studies have focused on the maternal physiological mechanisms that promote attachment (e.g. mothers’ automatic responses to infant faces and/or cries, and relatively less have examined infant physiology. Thus, the physiological mechanisms regulating infant bonding behaviors remain largely undefined. This review elucidates some of the neurobiological mechanisms governing social bonding and cooperation in humans by focusing on maternal carrying and its beneficial effect on mother-infant interaction in mammalian species (e.g. in humans, big cats and rodents. These studies show that infants have a specific calming response to maternal carrying. A human infant carried by his/ her walking mother exhibits a rapid heart rate decrease, and immediately stops voluntary movement and crying compared to when he/ she is held in a sitting position. Furthermore, strikingly similar responses were identified in mouse rodents, who exhibit immobility, diminished ultra-sonic vocalizations and heart rate. In general, the studies described in the current review demonstrate the calming effect of maternal carrying to be comprised of a complex set of behavioral and physiological components, each of which has a specific postnatal time window and is orchestrated in a well-matched manner with the maturation of the infants. Such reactions could have been evolutionarily adaptive in mammalian mother-infant interactions. The findings have implications for parenting practices in developmentally normal populations. In addition, we propose that infants’ physiological response may be useful in clinical assessments as we discuss possible implications on early screening for child psychopathology (e.g. Autism Spectrum Disorders, and Perinatal Brain Disorders.

  1. The calming effect of maternal carrying in different mammalian species.

    Science.gov (United States)

    Esposito, Gianluca; Setoh, Peipei; Yoshida, Sachine; Kuroda, Kumi O

    2015-01-01

    Attachment theory postulates that mothers and their infants possess some basic physiological mechanisms that favor their dyadic interaction and bonding. Many studies have focused on the maternal physiological mechanisms that promote attachment (e.g., mothers' automatic responses to infant faces and/or cries), and relatively less have examined infant physiology. Thus, the physiological mechanisms regulating infant bonding behaviors remain largely undefined. This review elucidates some of the neurobiological mechanisms governing social bonding and cooperation in humans by focusing on maternal carrying and its beneficial effect on mother-infant interaction in mammalian species (e.g., in humans, big cats, and rodents). These studies show that infants have a specific calming response to maternal carrying. A human infant carried by his/her walking mother exhibits a rapid heart rate decrease, and immediately stops voluntary movement and crying compared to when he/she is held in a sitting position. Furthermore, strikingly similar responses were identified in mouse rodents, who exhibit immobility, diminished ultra-sonic vocalizations and heart rate. In general, the studies described in the current review demonstrate the calming effect of maternal carrying to be comprised of a complex set of behavioral and physiological components, each of which has a specific postnatal time window and is orchestrated in a well-matched manner with the maturation of the infants. Such reactions could have been evolutionarily adaptive in mammalian mother-infant interactions. The findings have implications for parenting practices in developmentally normal populations. In addition, we propose that infants' physiological response may be useful in clinical assessments as we discuss possible implications on early screening for child psychopathology (e.g., autism spectrum disorders and perinatal brain disorders).

  2. High Speed Carry Select Adder for ALU Blocks

    Directory of Open Access Journals (Sweden)

    J.Rama Krishna Reddy

    2013-06-01

    Full Text Available The regular SQRT CSLA consists of two RCA blocks with carry input as 0 and 1.The Final sum will be selected from multiplexers (Mux by the carry out generated by the pervious block. This paper, proposes an area and delay efficient carry select adder with logical reduction of excess redundant hardware. In the proposed architecture, we had implemented the RCA with carry input as 1, only with Mux, Or gate and And gate. For 16-bit regular SQRT CSLA there is a reduction of basic logic gates from 434 to 323.The delay is reduced by replacing Full-adder with half-adder in first bit of every RCA in theproposed architecture. This will reduces the number of Iterations required to get the final sum. The proposed architecture shows that there is reduction of area and delay. Based on this architecture, wedesigned 4-bit,8-bit,16-bit and 32-bit Square-root CSLA (SQRT CSLA and compared with the regular SQRT CSLA. In this work, we evaluated the performance of the proposed design in 90-ηm CMOS Technology in Cadence Tools. The result analysis shows that, the proposed SQRT CSLA of 4-bit, 8-bit 16- bit and 32-bit has a reduction of 31.74%, 30.13%, 21.92% and 21.76 % respectively compared with regular SQRT CSLA in area. The delay of Proposed SQRT CSLA of 4-bit,8-bit 16-bit and 32-bit are reduce by 27.47%, 17.23%, 14.32% and 11.63% respectively.

  3. Gluteus medius and thigh muscles electromyography during load carrying walking

    Directory of Open Access Journals (Sweden)

    Petr Šťastný

    2015-11-01

    Full Text Available This study compares the electromyographic (EMG peak amplitude changes of gluteus medius (Gmed, vastus medialis (VMO, vastus lateralis (VL and biceps femoris (BF during load carrying walking due to the increased load. The percentage of maximum isometric voluntary contractions (%MVIC of both limbs and 3D kinematic of lower limbs were detected on eighteen resistance-trained men (mean age ± SD, 31 ± 3.4 years while carrying loads of 25, 50 and 75% of their body mass (BM. The repeated measurement ANOVA was used to evaluate the differences in muscles %MVIC and 3D kinematics at all load conditions. Significant differences were found for Gmed %MVIC (F3,99 = 19.8, p < 0.001. Gmed activity was significantly different between load carrying walking with 25% of BM (mean ± SD, 20 ± 12%MVIC, 50% of BM (32 ± 17%MVIC and 75% of BM (45 ± 26%MVIC condition. Differences were found in hip flexion at Gmed EMG peak (F3,96 = 14, p < 0.001, between 25% of BM (18 ± 11° and 50% of BM (29 ± 7°. No significant differences were found for thigh muscles, when thigh muscle activity did not exceed 30%MVIC even at 75% of BM condition. Load carrying walking is an exercise which activates Gmed more than thigh muscles. This exercise increases the Gmed activity along with increased loads and it should be regarded as a complex Gmed strengthening exercise. This exercise is recommended for strengthening the Gmed with low activation of VL and VMO.

  4. Self-timed Manchester chain carry propagate adder

    OpenAIRE

    Escribà, J; Carrasco, Juan A.

    1996-01-01

    The authors present a self-timed adder that uses two Manchester chains to propagate carries in a two-rail code. With the inclusion of buffers in the chains, the adder meets the timing conditions typical of an asynchronous design based in the ‘bundled-data, bounded-delay’ model and is signifcantly faster than self-timed adders with restoring logic and similar complexity.

  5. Low Power 256-bit Modified Carry Select Adder

    Directory of Open Access Journals (Sweden)

    P. Ramani

    2014-09-01

    Full Text Available Carry Select Adder (CSLA is one of the high speed adders used in many computational systems to perform fast arithmetic operations. When compared to earlier Ripple Carry Adder and Carry Look Ahead Adder, Regular CSLA (R-CSLA is observed to provide optimized results in terms of area. This study proposes an efficient method which replaces the RCA using BEC. The modified CSLA architecture has been developed using gate-level modification to significantly reduce the delay and power of the CSLA. Based on this modification 8-, 16-, 32-, 64- and 128-bit Square-Root CSLA (SQRT CSLA architecture have been developed and compared with the regular SQRT CSLA architecture. The proposed design for 256-bit has reduced power and delay as compared with the regular SQRT CSLA. Designs were developed using structural Verilog module and synthesized using Xilinx ISE simulator and the implementation is done in cadence RTL compiler using 0.18 µm technology. For 256-bit addition in this study, it is proposed to simple gate level modification which significantly reduces the power by 19.4% when compared with R-CSLA. The result analysis shows that the proposed architecture achieves two folded advantages in terms of delay and power.

  6. A portable virtual machine target for proof-carrying code

    DEFF Research Database (Denmark)

    Franz, Michael; Chandra, Deepak; Gal, Andreas

    2005-01-01

    Virtual Machines (VMs) and Proof-Carrying Code (PCC) are two techniques that have been used independently to provide safety for (mobile) code. Existing virtual machines, such as the Java VM, have several drawbacks: First, the effort required for safety verification is considerable. Second and mor...... simultaneously providing efficient justin-time compilation and target-machine independence. In particular, our approach reduces the complexity of the required proofs, resulting in fewer proof obligations that need to be discharged at the target machine.......Virtual Machines (VMs) and Proof-Carrying Code (PCC) are two techniques that have been used independently to provide safety for (mobile) code. Existing virtual machines, such as the Java VM, have several drawbacks: First, the effort required for safety verification is considerable. Second and more...... subtly, the need to provide such verification by the code consumer inhibits the amount of optimization that can be performed by the code producer. This in turn makes justin-time compilation surprisingly expensive. Proof-Carrying Code, on the other hand, has its own set of limitations, among which...

  7. Targeted drug-carrying bacteriophages as antibacterial nanomedicines.

    Science.gov (United States)

    Yacoby, Iftach; Bar, Hagit; Benhar, Itai

    2007-06-01

    While the resistance of bacteria to traditional antibiotics is a major public health concern, the use of extremely potent antibacterial agents is limited by their lack of selectivity. As in cancer therapy, antibacterial targeted therapy could provide an opportunity to reintroduce toxic substances to the antibacterial arsenal. A desirable targeted antibacterial agent should combine binding specificity, a large drug payload per binding event, and a programmed drug release mechanism. Recently, we presented a novel application of filamentous bacteriophages as targeted drug carriers that could partially inhibit the growth of Staphylococcus aureus bacteria. This partial success was due to limitations of drug-loading capacity that resulted from the hydrophobicity of the drug. Here we present a novel drug conjugation chemistry which is based on connecting hydrophobic drugs to the phage via aminoglycoside antibiotics that serve as solubility-enhancing branched linkers. This new formulation allowed a significantly larger drug-carrying capacity of the phages, resulting in a drastic improvement in their performance as targeted drug-carrying nanoparticles. As an example for a potential systemic use for potent agents that are limited for topical use, we present antibody-targeted phage nanoparticles that carry a large payload of the hemolytic antibiotic chloramphenicol connected through the aminoglycoside neomycin. We demonstrate complete growth inhibition toward the pathogens Staphylococcus aureus, Streptococcus pyogenes, and Escherichia coli with an improvement in potency by a factor of approximately 20,000 compared to the free drug.

  8. Violence and weapon carrying in music videos. A content analysis.

    Science.gov (United States)

    DuRant, R H; Rich, M; Emans, S J; Rome, E S; Allred, E; Woods, E R

    1997-05-01

    The positive portrayal of violence and weapon carrying in televised music videos is thought to have a considerable influence on the normative expectations of adolescents about these behaviors. To perform a content analysis of the depictions of violence and weapon carrying in music videos, including 5 genres of music (rock, rap, adult contemporary, rhythm and blues, and country), from 4 television networks and to analyze the degree of sexuality or eroticism portrayed in each video and its association with violence and weapon carrying, as an indicator of the desirability of violent behaviors. Five hundred eighteen videos were recorded during randomly selected days and times of the day from the Music Television, Video Hits One, Black Entertainment Television, and Country Music Television networks. Four female and 4 male observers aged 17 to 24 years were trained to use a standardized content analysis instrument. Interobserver reliability testing resulted in a mean (+/- SD) percentage agreement of 89.25% +/- 7.10% and a mean (+/- SD) kappa of 0.73 +/- 0.20. All videos were observed by rotating 2-person, male-female teams that were required to reach agreement on each behavior that was scored. Music genre and network differences in behaviors were analyzed with chi 2 tests. A higher percentage (22.4%) of Music Television videos portrayed overt violence than Video Hits One (11.8%), Country Music Television (11.8%), and Black Entertainment Television (11.5%) videos (P = .02). Rap (20.4%) had the highest portrayal of violence, followed by rock (19.8%), country (10.8%), adult contemporary (9.7%), and rhythm and blues (5.9%) (P = .006). Weapon carrying was higher on Music Television (25.0%) than on Black Entertainment Television (11.5%), Video Hits One (8.4%), and Country Music Television (6.9%) (P rhythm and blues (6.9%), and country (6.3%) videos (P = .002). The videos with the highest level of sexuality or eroticism were found to be less likely to contain violence (P < or

  9. The carrying capacity of a tourist destination. The case of a coastal Italian city

    OpenAIRE

    Maggi, Elena; Fredella, Franco Lorenzo

    2011-01-01

    In the last decades the world tourist flows rapidly grew and travel and tourism has become one of the world’s highest priority industries and employers. According to UNWTO world tourism barometer, in 2008 international tourist arrivals reached 919 million (880 million in 2009, a cause of the international recession), with a growth of 72% since 1995. Italy, which accounts in 2009 43 millions of tourist arrivals, is one of the most preferred destinations. Tourism gives an important contribu...

  10. Efficient Design of Ripple Carry Adder and Carry Skip Adder with Low Quantum Cost and Low Power Consumption

    OpenAIRE

    Nidhi; Gurinderpal Singh

    2014-01-01

    The addition of two binary numbers is the important and most frequently used arithmetic process on microprocessors, digital signal processors (DSP), and data-processing application-specific integrated circuits (ASIC). Therefore, binary adders are critical structure blocks in very large-scale integrated (VLSI) circuits. Their effective application is not trivial because a costly carry spread operation involving all operand bits has to be achieved. Many different circuit constru...

  11. Killing cancer cells by targeted drug-carrying phage nanomedicines

    Directory of Open Access Journals (Sweden)

    Yacoby Iftach

    2008-04-01

    Full Text Available Abstract Background Systemic administration of chemotherapeutic agents, in addition to its anti-tumor benefits, results in indiscriminate drug distribution and severe toxicity. This shortcoming may be overcome by targeted drug-carrying platforms that ferry the drug to the tumor site while limiting exposure to non-target tissues and organs. Results We present a new form of targeted anti-cancer therapy in the form of targeted drug-carrying phage nanoparticles. Our approach is based on genetically-modified and chemically manipulated filamentous bacteriophages. The genetic manipulation endows the phages with the ability to display a host-specificity-conferring ligand. The phages are loaded with a large payload of a cytotoxic drug by chemical conjugation. In the presented examples we used anti ErbB2 and anti ERGR antibodies as targeting moieties, the drug hygromycin conjugated to the phages by a covalent amide bond, or the drug doxorubicin conjugated to genetically-engineered cathepsin-B sites on the phage coat. We show that targeting of phage nanomedicines via specific antibodies to receptors on cancer cell membranes results in endocytosis, intracellular degradation, and drug release, resulting in growth inhibition of the target cells in vitro with a potentiation factor of >1000 over the corresponding free drugs. Conclusion The results of the proof-of concept study presented here reveal important features regarding the potential of filamentous phages to serve as drug-delivery platform, on the affect of drug solubility or hydrophobicity on the target specificity of the platform and on the effect of drug release mechanism on the potency of the platform. These results define targeted drug-carrying filamentous phage nanoparticles as a unique type of antibody-drug conjugates.

  12. [Simple locomotion and during load carrying in pregnant women].

    Science.gov (United States)

    Golomer, E; Ducher, D; Arfi, G S; Sud, R

    1991-01-01

    There have been few studies of the way women walk in pregnancy, though some of the causes of low back ache of which they complain have only been partially worked out. This is why this study has been carried out on ten women between the third and eighth month of pregnancy. The speed at which they walk and the parameters of the gait as well as the localization of the centre of gravity when keeping upright have been measured in these pregnant women as well as in twenty control women of the same age. The results show that the speed at which they walk whether with or without carrying a weight usually is identical at the beginning and the end of pregnancy. When walking normally the size of the steps taken are no larger in pregnant women than in the control patients (p less than 0.05). Though the results are not statistically significant the rhythm of the steps is faster as well as their being a reduction in the length of the steps between the third and eighth month of pregnancy. When carrying a weight the length of the steps does not change greatly with pregnancy (p less than 0.05) and it would seem therefore to be a good way of assessing the changes that locomotion undergoes in pregnancy. The fact that women do not walk faster or slower can give evidence that they adapt to the change in posture that happens in pregnancy and they make the best possible biomechanical use of the parameters of walking in order to economise total energy output of the organism.(ABSTRACT TRUNCATED AT 250 WORDS)

  13. Design and Verification of Advanced Carry Select Adder

    Directory of Open Access Journals (Sweden)

    Guru Dixit Chepuri

    2014-05-01

    Full Text Available Design ofareaefficient data pathlogicsystems formsthelargestareasofresearch inVLSIsystem design.Indigital adders, thespeed of addition islimitedbythetimerequired totransmit a carrythroughtheadder.CarrySelectAdder (CSA isoneofthefastestadders usedinmanydata-processingprocessorstoperform fastarithmetic functions. Fromthestructure oftheCSA,itisclear thatthereisscopeforreducing thearea and powerintheCSA. This work usesasimpleandefficient gate-level modification todrasticallyreducetheareaandpower oftheCSA.Basedonthismodification 16,32,64 and128-bitsquare-root CSA(SQRT CSA architectureshavebeendevelopedandcomparedwith theregularSQRTCSAarchitecture. Theproposed designhasreducedarea and powerascompared withtheregular SQRTCSA.Thisworkestimates theperformanceof theproposed designsintermsofpower,areaand isimplementedusingXilinxISE and synthesized using cadence in 90nm technology.

  14. Optimal Final Carry Propagate Adder Design for Parallel Multipliers

    CERN Document Server

    B., Ramkumar

    2011-01-01

    Based on the ASIC layout level simulation of 7 types of adder structures each of four different sizes, i.e. a total of 28 adders, we propose expressions for the width of each of the three regions of the final Carry Propagate Adder (CPA) to be used in parallel multipliers. We also propose the types of adders to be used in each region that would lead to the optimal performance of the hybrid final adders in parallel multipliers. This work evaluates the complete performance of the analyzed designs in terms of delay, area, power through custom design and layout in 0.18 um CMOS process technology.

  15. Reflection of Naturalism and Darwinism in Dreiser' s Sister Carrie

    Institute of Scientific and Technical Information of China (English)

    王静

    2009-01-01

    Naturalism is a significant school of literature in American literary history. This thesis mainly reviews the background, development, and characteristic of the realism and naturalism literature, and states the significant person in Naturalism literature-Dreiser and his. important literary position and analyzes the reflection of naturalism and Darwinism in Sister Carrie. Through the analysis of determinism, desire, ethics and detail description, a conclusion is made: the factors affecting the novel' s writing not only include the author' s own experiences but also the main social ideology in his living years.

  16. The information carrying capacity of a cosmological constant

    CERN Document Server

    Simidzija, Petar

    2016-01-01

    We analyze the exchange of information in different cosmological backgrounds when sender and receiver are timelike separated and communicate through massless fields (without the exchange of light-signals). Remarkably, we show that the dominance of a cosmological constant makes the amount of recoverable information imprinted in the field by the sender extremely resilient: it does not decay in time or with the spatial separation of sender and receiver, and it actually increases with the rate of expansion of the Universe. This is in stark contrast with the information carried by conventional light-signals and with previous results on timelike communication through massless fields in matter dominated cosmologies.

  17. The carry-over effect does not influence football results.

    OpenAIRE

    Goossens, Dries; Spieksma, Frederik

    2012-01-01

    In a round robin tournament, it is often believed that each team has an effect on its opponent, which carries over to the next game of that opponent. Indeed, if team A plays against team B, and subsequently against team C, A’s performance against C may have been affected by B, and we say that team C receives a carryover effect from B. For instance, if team B is a very strong team, then team A could be exhausted and discouraged after this game, which could benefit its next opponent, team C. Cl...

  18. Langkawi Island, Social Aspect and the Carrying Capacity

    Directory of Open Access Journals (Sweden)

    Mohamad Diana

    2014-01-01

    Full Text Available The aptitude to convince a range of preferences has facilitated the island tourism attractions to achieve international recognition and at present KILIM Geopark is enjoyed by a prominent percentage of individuals wide-reaching. Conventional knowledge has that the island attractions are operating on the limited immobile resources, of which, have raised the scholars’ concerns over the carrying capacity issue. When analyzing carrying capacity, scholars have traditionally focused on the environmental part, hence, this working paper is motivated to convey onto the table issues relating to the social characteristics. This particular paper employed the self-administered questionnaire survey instrument which was structured to answer the two-fold objective specifically the tourists’ satisfaction level with their tourism experience and knowledge gap in relation to improving the island tourism. Targeting the tourists with minimum age of 18, this working paper collects information on the tourists’ perception towards hospitality, facilities and safety issues. In addition, this working paper comes to scrutinize different results of demographic factors as compared to what have been documented by earlier studies. Besides, it is learned that ‘safety issue’ variable plays an important role when it comes to the following factors: tourist arrival, access to facilities and tourism experience.

  19. Are food brands that carry light claims different?

    DEFF Research Database (Denmark)

    Sjostrom, Therese; Corsi, Armando Maria; Driesener, Carl

    2014-01-01

    Little is known about the market performance of brands that carry light claims (e.g. low fat, low sugar) in comparison to their regular counterparts. In order to fill this gap, we explore whether light brands perform similarly to regular brands in terms of a) brand performance measures, such as m......Little is known about the market performance of brands that carry light claims (e.g. low fat, low sugar) in comparison to their regular counterparts. In order to fill this gap, we explore whether light brands perform similarly to regular brands in terms of a) brand performance measures......, such as market share and penetration, b) loyalty levels, and c) customer sharing. We analyse three product categories (Cola, Flavoured Carbonated Beverages and Margarine) using UK household panel data provided by Kantar. The results show that when considering standard brand performance measures (i.e. market...... share, penetration and purchase frequency), regular brands receive higher brand performance measures than light brands. However, when considering repeat purchase loyalty, light brands achieve greater levels of loyalty than their regular counterparts. Finally, light brands share their buyers more...

  20. Kinematic analysis of males with transtibial amputation carrying military loads

    Directory of Open Access Journals (Sweden)

    Barri L. Schnall, MPT

    2015-03-01

    Full Text Available The biomechanical responses to load carriage, a common task for dismounted troops, have been well studied in nondisabled individuals. However, with recent shifts in the rehabilitation and retention process of injured servicemembers, there remains a substantial need for understanding these responses in persons with lower-limb amputations. Temporal-spatial and kinematic gait parameters were analyzed among 10 male servicemembers with unilateral transtibial amputation (TTA and 10 uninjured male controls. Participants completed six treadmill walking trials in all combinations of two speeds (1.34 and 1.52 m/s and three loads (none, 21.8, and 32.7 kg. Persons with TTA exhibited biomechanical compensations to carried loads that are comparable to those observed in uninjured individuals. However, several distinct gait changes appear to be unique to those with TTA, notably, increased dorsiflexion (deformation of the prosthetic foot/ankle, less stance knee flexion on the prosthetic limb, and altered trunk forward lean/excursion. Such evidence supports the need for future work to assess the risk for overuse injuries with carried loads in this population in addition to guiding the development of adaptive prosthetic feet/components to meet the needs of redeployed servicemembers or veterans/civilians in physically demanding occupations.

  1. c-Myc-Induced Extrachromosomal Elements Carry Active Chromatin

    Directory of Open Access Journals (Sweden)

    Greg Smith

    2003-03-01

    Full Text Available Murine Pre-13 lymphocytes with experimentally activated MycER show both chromosomal and extrachromosomal gene amplification. In this report, we have elucidated the size, structure, functional components of c-Myc-induced extrachromosomal elements (EEs. Scanning electron microscopy revealed that EEs isolated from MycER-activated Pre-B+ cells are an average of 10 times larger than EEs isolated from non-MycER-activated control Pre-B- cells. We demonstrate that these large c-Myc-induced EEs are associated with histone proteins, whereas EEs of non-MycER-activated Pre B- cells are not. Immunohistochemistry and Western blot analyses using pan -histone-specific, histone H3 phosphorylation-specific, histone H4 acetylation-specific antibodies indicate that a significant proportion of EEs analyzed from MycER-activated cells harbors transcriptionally competent and/or active chromatin. Moreover, these large, c-Myc-induced EEs carry genes. Whereas the total genetic make-up of these c-Myc-induced EEs is unknown, we found that 30.2% of them contain the dihydrofolate reductase (DHFR gene, whereas cyclin C (CCNC was absent. In addition, 50% of these c-Myc-activated Pre-B+ EEs incorporated bromodeoxyuridine (BrdU, identifying them as genetic structures that self-propagate. In contrast, EEs isolated from non-Myc-activated cells neither carry the DHFR gene nor incorporate BrdU, suggesting that c-Myc deregulation generates a new class of EEs.

  2. The Population Carrying Capacity of Water Resources in Yulin City

    Institute of Scientific and Technical Information of China (English)

    Lijuan; DANG; Yong; XU; Zhiqiang; WANG

    2014-01-01

    Assessing the water resource carrying capacity is beneficial for measuring the scale of industry and population agglomeration,and also avoiding the contradiction between increasing people and decreasing available water resource,due to the expansion of industry and city size.Based on the prediction model of optimum population development size,by using hydrological data,also with the demographic data from 1956 to 2010,this article analyzes and predicts the urban moderate scale under the limit of the water resource in the future of Yulin City by GIS. The main conclusions are as follows. There is growing tendency of water resources overloading. According to the result of model simulation,by2015,the overload rate of population size will be 1. 04. By 2020,the overload rate of population size will grow up to 1. 08. The oversized population mainly comes from cities and towns. The overload rate for cities and towns in 2015 and 2020 is 1. 89 and 1. 73,respectively. With the expansion of cities and industries,suburban areas could have a great potential for carrying population,because lots of suburban people may move to cities and towns according to prediction. In view of the above-mentioned facts,the population size should be controlled in a reasonable range.

  3. A Novel Framework to Carry Out Cloud Penetration Test

    Directory of Open Access Journals (Sweden)

    Jianbin Hu

    2011-04-01

    Full Text Available in current cloud services, users put their data and resources into the cloud so as to enjoy the on-demand high quality applications and services. Different from the conventional services, users in cloud services lose control of their data which is instead manipulated by the large-scale cloud. Therefore, cloud service providers (CSP guarantee that the cloud which they provide is of high confidence in accuracy and integrity. Traditional penetration test is carried out manually and has low efficiency. In this paper, we propose FPTC, a novel framework of penetration test in cloud environment. In FPTC, there are managers, executors and toolkits. FPTC managers guide FPTC executors to gather information from the cloud environment, generate appropriate testing scenarios, run matched tools in the toolkit and collect test results to do evaluation. The capacity and quality of the toolkit is a key issue in FPTC. We develop a prototype in which FPTC is implemented and the experimental results show that FPTC is helpful to automatically carry out penetration test in cloud environment.

  4. An Eco-feminist Comparison between Sister Carrie and My Antonia

    Institute of Scientific and Technical Information of China (English)

    刘翌

    2014-01-01

    According to human history, there are varieties of ways through which the feminine aspect of nature faced and in many cases, overcame oppression. One of the ways this phenomenon displays itself is in the literary works that we deem as realis⁃tic and an expression of the norms and customs of the society in question. Sister Carrie and My Antonia are two such literary pieces that embody the struggles and triumphs of women in the 19th and most of the early 20th century. In creating such monu⁃mental and naturalistic adaptations, both authors are able to present the case of two migratory women from different backgrounds but confined by the norms and mannerisms of the society around them. The struggles that each of these characters undergoes is an expression of the underlying constraints that the paternal and chauvinistic society of their time places upon both women and the natural world. The eco-feminist agenda, however, gets a more elaborate representation in My Antonia than in Sister Carrie due to a variety of factors that serve to illuminate the differences between these two iconic stories. This paper makes a thorough comparison between two literary works—Sister Carrie by Theodore Dreiser and My Antonia by Willa Cather from the perspec⁃tive of eco-feminism.

  5. Modelling of carry-over in recovery furnaces

    Energy Technology Data Exchange (ETDEWEB)

    Fakhrai, Reza [Royal Inst. of Tech., Stockholm (Sweden). Dept. of Metallurgy

    2000-04-01

    Development of mathematical modelling of the combustion process in the furnace of recovery boilers is the subject of this work. This work as a continuation of many years of modelling efforts carried out at KTH/Vaerme- och Ugnsteknik focussed particularly on: char bed modelling; droplets-wall interaction modelling; and carry-over modelling. The char bed model has been studied. Droplets/parcels were considered as a single reactor working independently of the other droplets. The mass of the droplets was not distributed uniformly but induced in the landing place. The droplets hitting the char bed will stick to it and they are alive and part of the calculation. In this way the distribution of the mass on the char bed is only dependent on the parameters which effect flight history such as droplet/parcel diameter, boilers flow field, etc. The droplet- wall interaction model has been studied and found to be very important for obtaining the correct temperature distribution in the recovery furnace. The new approach is based on removal of droplets which hits the wall in the upper part of the recovery boiler from carryover calculation. This model has been proposed and implemented into the GRFM (General Recovery Furnace Model). The carryover modelling effort was based on mass balance in which the number and physical statistics of the droplets/parcel were estimated and the amount of unburned mass was calculated. All of the above listed models were tested together with all other models of heat and mass transfer processes in recovery furnaces using a GRFM. Three-dimensional numerical simulations of the industrial recovery boiler (63 kg/s, 82 bar, 480 deg C) were performed. The number of grid was 232,000 and the number of air ports in this simulation was 178. The air entering the furnace by these ports has different flow rates. Flow and temperature fields as well as species distributions were calculated. The results show good agreement with previously published data and modelling

  6. What is the carrying capacity for fish in the ocean? A meta analysis of population dynamics of North Atlantic cod

    DEFF Research Database (Denmark)

    Myers, R.A.; MacKenzie, Brian; Bowen, K.G.;

    2001-01-01

    model 21 Atlanic cod (Gadus morhua) stocks in the North Atlantic assuming that the maximum reproductive rate and the carrying capacity per unit area are random variables. This method uses a nonlinear mixed model and is a natural approach to investigate how carrying capacity varies among populations. We...... used empirical Bayes techniques to estimate the maximum reproductive rate and carrying capacity of each stock. In all cases, the empirical Bayes estimates were biologically reasonable, whereas a stock by stock analysis occasionally yielded nonsensical parameter estimates (e.g., infinite values). Our...... analysis showed that the carrying capacity per unit area varied by more than 20-fold among populations and that much of this variation was related to temperature. That is, the carrying capacity per square kilometre declines as temperature increases....

  7. Carbohydrate nanotechnology: hierarchical assembly using nature's other information carrying biopolymers.

    Science.gov (United States)

    Han, Xu; Zheng, Yeting; Munro, Catherine J; Ji, Yiwen; Braunschweig, Adam B

    2015-08-01

    Despite their central role in directing some of the most complex biological processes, carbohydrates--nature's other information carrying biopolymer--have been largely ignored as building blocks for synthetic hierarchical assemblies. The non-stoichiometric binding and astronomical diversity characteristic of carbohydrates could lead to tantalizingly complex assembly algorithms, but these attributes simultaneously increase the difficulty of preparing carbohydrate assemblies and anticipating their behavior. Convergences in biotechnology, nanotechnology, polymer chemistry, surface science, and supramolecular chemistry have led to many recent important breakthroughs in glycan microarrays and synthetic carbohydrate receptors, where the idiosyncrasies of carbohydrate structure and binding are increasingly considered. We hope to inspire more researchers to consider carbohydrate structure, diversity, and binding as attractive tools for constructing synthetic hierarchical assemblies.

  8. Cognitive Load in Voice Therapy Carry-Over Exercises

    DEFF Research Database (Denmark)

    Iwarsson, Jenny; Morris, David Jackson; Balling, Laura Winther

    2017-01-01

    Purpose The cognitive load generated by online speech production may vary with the nature of the speech task. This article examines 3 speech tasks used in voice therapy carry-over exercises, in which a patient is required to adopt and automatize new voice behaviors, ultimately in daily spontaneous...... communication. Method Twelve subjects produced speech in 3 conditions: rote speech (weekdays), sentences in a set form, and semispontaneous speech. Subjects simultaneously performed a secondary visual discrimination task for which response times were measured. On completion of each speech task, subjects rated...... their experience on a questionnaire. Results Response times from the secondary, visual task were found to be shortest for the rote speech, longer for the semispontaneous speech, and longest for the sentences within the set framework. Principal components derived from the subjective ratings were found to be linked...

  9. Carry Trade e Risco Cambial: um Conto de Dois Fatores

    Directory of Open Access Journals (Sweden)

    Alex Luiz Ferreira

    2015-12-01

    Full Text Available Retornos da estratégia de carry trade tem sido explicados usando-se funções de utilidade inseparáveis no tempo que permitem prêmios de risco voláteis. Tipicamente tais funções mimetizam as preferências de economia fechada que dependem de bens duráveis e não duráveis. Este trabalho retorna a uma classificação mais tradicional, em macroeconomia internacional, de consumo entre bens domésticos e importados. O modelo é aplicado para países que representam 98,2% do volume mundial do comércio bilateral de câmbio. Reporta-se uma melhora acentuada na significância dos betas de consumo.

  10. Filaggrin compound heterozygous patients carry mutations in trans position

    DEFF Research Database (Denmark)

    Carlsen, Berit C; Meldgaard, Michael; Johansen, Jeanne D

    2013-01-01

    ; however, this has not been scientifically investigated. Two different FLG null mutations in the same individual may be in trans position, meaning that each mutation locates to a different allele functionally equivalent to homozygosity, or may be in cis position, meaning that both mutations locate...... to the same allele functionally equivalent to heterozygosity. To experimentally investigate allelic in cis versus in trans configuration of the two most common filaggrin (FLG) mutations (R501X and 2282del4) in compound heterozygous individuals. Testing for in cis or in trans allele configuration was performed...... compound heterozygous individuals were found to carry the two mutations in trans position. FLG null mutation compound heterozygous individuals can be considered functionally equivalent to FLG null mutation homozygosity for any of the two mutations....

  11. Fatigue Analysis of Load-Carrying Fillet Welds

    DEFF Research Database (Denmark)

    Sørensen, John Dalsgaard; Tychsen, Jesper; Andersen, Jens Ulfkjær

    2006-01-01

    is a doubler plate connection, which is often applied in connection with modifications of offshore structures. As a part of the present work, fatigue tests have been performed with test specimens fabricated by the current industry standard for welded offshore steel structures. The fatigue tests show......The fatigue strength of load-carrying fillet welds is, in most codes of practice, performed neglecting the influence of bending in the weld throat section. However, some commonly applied structural details give rise to significant bending in the weld throat section. An example of such a detail...... that the degree of bending (DOB) has an influence on the fatigue lifetime. The fatigue lifetime decreases significantly when increasing the bending stress. In order to take into account the effect of the bending, a new fatigue stress definition applicable for fillet welds failing through the weld is presented...

  12. Overview of the activities carried out at the FEBEX site

    Energy Technology Data Exchange (ETDEWEB)

    Missana, T.; Buil, B.; Garralon, A.; Gomez, P. [CIEMAT, Dept. de Medioambien te, 28040 Madrid (Spain); Perez-Estaun, A.; Carbonell, R. [Inst. Jaume Almera, CSIC (Spain); Suso, J.; Carretero, G.; Bueno, J.; Martinez, L. [AITEMIN (Spain) ; Hernan, P. [ENRESA (Spain)

    2007-06-15

    One of the main aim of WP 4.1 and 4.2 is to study solute migration mechanisms in crystalline host-rock in realistic conditions. Many organisations are participating in a joint study that is being performed in the FEBEX gallery (NAGRA's Grimsel Test Site, GTS, Switzerland). The FEBEX experiment reproduces at a real scale a high-level waste repository in granite and was installed more than 9 years ago. At moment, it represents the most realistic environment where the processes affecting radionuclide migration from the bentonite to granite can be studied. This paper summarises the main activities carried out at the FEBEX site during the second year of the project.

  13. An innovative method for water resources carrying capacity research--Metabolic theory of regional water resources.

    Science.gov (United States)

    Ren, Chongfeng; Guo, Ping; Li, Mo; Li, Ruihuan

    2016-02-01

    The shortage and uneven spatial and temporal distribution of water resources has seriously restricted the sustainable development of regional society and economy. In this study, a metabolic theory for regional water resources was proposed by introducing the biological metabolism concept into the carrying capacity of regional water resources. In the organic metabolic process of water resources, the socio-economic system consumes water resources, while products, services and pollutants, etc. are output. Furthermore, an evaluation index system which takes into the characteristics of the regional water resources, the socio-economic system and the sustainable development principle was established based on the proposed theory. The theory was then applied to a case study to prove its availability. Further, suggestions aiming at improving the regional water carrying capacity were given on the basis of a comprehensive analysis of the current water resources situation.

  14. Streptococcus lutetiensis Bacteremia. First Clindamycin Resistant Isolate Carrying lnuB Gene

    OpenAIRE

    Almuzara, Marisa; Bonofiglio, Laura; CITTADINI, Roberto Arnaldo; Vera Ocampo, C.; Montilla, A.; del Castillo, M.; Ramirez, Maria Soledad; Mollerach, Marta Eugenia; C. Vay

    2015-01-01

    First Case of Streptococcus lutetiensis Bacteremia Involving a Clindamycin-Resistant Isolate Carrying the lnuB Gene Fil: Almuzara, Marisa. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Bioquímica Clínica; Argentina; Fil: Bonofiglio, Laura. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología; Argentina; Fil: Cittadini, Roberto Arnaldo. Instituto Nacional de Tecnologia Agropecuaria;...

  15. Excretion pattern of aflatoxins in buffalo milk and carry-over in mozzarella cheese

    Directory of Open Access Journals (Sweden)

    A. Gualla

    2011-03-01

    Full Text Available Some raw materials, used in animal feeding, can be contaminated by aflatoxins (AF. All the mammals that ingest AFB1, excrete small amounts of the hydroxylated metabolite aflatoxin M1 (AFM1 in their milk (Wood 1991. In the case of cow’s milk, the percentage excreted is 1-3% of that ingested (Veldman et al. 1992. AFM1 has been categorised as a class 2B, possible human carcinogen. AFM1 is associated with the protein fraction of milk and hence it is carried-over to cheese and to other milk products (Brackett and Marth, 1982....

  16. Streptococcus lutetiensis Bacteremia. First Clindamycin Resistant Isolate Carrying lnuB Gene

    OpenAIRE

    Almuzara, Marisa; Bonofiglio, Laura; Cittadini, Roberto Arnaldo; Vera Ocampo, C.; Montilla, A.; Del Castillo, M.; Ramirez, Maria Soledad; Mollerach, Marta Eugenia; C. Vay

    2015-01-01

    First Case of Streptococcus lutetiensis Bacteremia Involving a Clindamycin-Resistant Isolate Carrying the lnuB Gene Fil: Almuzara, Marisa. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Bioquímica Clínica; Argentina; Fil: Bonofiglio, Laura. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Microbiología, Inmunología y Biotecnología; Argentina; Fil: Cittadini, Roberto Arnaldo. Instituto Nacional de Tecnologia Agropecuaria;...

  17. Bartonella-like bacteria carried by domestic mite species.

    Science.gov (United States)

    Kopecký, Jan; Nesvorná, Marta; Hubert, Jan

    2014-01-01

    Bacteria of the genus Bartonella are carried by haematophagous mites, ticks, fleas and flies, and attack the erythrocytes of mammals. Here we describe a Bartonella-like clade, a distinct group related to Bartonellaceae, in stored-product mites (Acari: Astigmata) and a predatory mite Cheyletus eruditus (Acari: Prostigmata) based on the analysis of cloned 16S rRNA gene sequences. By using the clade-specific primers, closely related Bartonella-like 16S rRNA sequences were amplified from both laboratory colonies and field strains of three synanthropic mite species (Acarus siro, Lepidoglyphus destructor and Tyrophagus putrescentiae) and a predatory mite. Altogether, sequences of Bartonella-like bacteria were found in 11 strains, but were not detected in Dermatophagoides farinae and D. pteronyssinus and two strains of L. destructor. All obtained sequences formed a separate cluster branching as a sister group to Bartonellaceae and related to other separate clusters comprising uncultured bacterial clones from human skin and hemipteran insects (Nysius plebeius and Nysius sp.). The classification of sequences into operational taxonomic units (OTUs) showed a difference between A. siro and T. putrescentiae suggesting that the Bartonella-like bacteria are different in these two mite species. However, species specific sequences in separate OTUs were observed also for C. eruditus. Possible symbiotic interactions between Bartonella-like bacteria and their mite hosts are discussed.

  18. Saliva microbiota carry caries-specific functional gene signatures.

    Directory of Open Access Journals (Sweden)

    Fang Yang

    Full Text Available Human saliva microbiota is phylogenetically divergent among host individuals yet their roles in health and disease are poorly appreciated. We employed a microbial functional gene microarray, HuMiChip 1.0, to reconstruct the global functional profiles of human saliva microbiota from ten healthy and ten caries-active adults. Saliva microbiota in the pilot population featured a vast diversity of functional genes. No significant distinction in gene number or diversity indices was observed between healthy and caries-active microbiota. However, co-presence network analysis of functional genes revealed that caries-active microbiota was more divergent in non-core genes than healthy microbiota, despite both groups exhibited a similar degree of conservation at their respective core genes. Furthermore, functional gene structure of saliva microbiota could potentially distinguish caries-active patients from healthy hosts. Microbial functions such as Diaminopimelate epimerase, Prephenate dehydrogenase, Pyruvate-formate lyase and N-acetylmuramoyl-L-alanine amidase were significantly linked to caries. Therefore, saliva microbiota carried disease-associated functional signatures, which could be potentially exploited for caries diagnosis.

  19. Certificate size reduction in Abstraction-Carrying Code

    CERN Document Server

    Albert, Elvira; Puebla, Germán; Hermenegildo, Manuel

    2010-01-01

    Carrying Code (ACC) has recently been proposed as a framework for mobile code safety in which the code supplier provides a program together with an abstraction (or abstract model of the program) whose validity entails compliance with a predefined safety policy. The advantage of providing a (fixpoint) abstraction to the code consumer is that its validity is checked in a single pass (i.e., one iteration) of an abstract interpretation-based checker. A main challenge to make ACC useful in practice is to reduce the size of certificates as much as possible while at the same time not increasing checking time. The intuitive idea is to only include in the certificate information that the checker is unable to reproduce without iterating. We introduce the notion of reduced certificate which characterizes the subset of the abstraction which a checker needs in order to validate (and re-construct) the full certificate in a single pass. Based on this notion, we instrument a generic analysis algorithm with the necessary exte...

  20. Carrying photosynthesis genes increases ecological fitness of cyanophage in silico.

    Science.gov (United States)

    Hellweger, Ferdi L

    2009-06-01

    Several viruses infecting marine cyanobacteria carry photosynthesis genes (e.g. psbA, hli) that are expressed, yield proteins (D1, HLIP) and help maintain the cell's photosynthesis apparatus during the latent period. This increases energy and speeds up virus production, allowing for a reduced latent period (a fitness benefit), but it also increases the DNA size, which slows down new virus production and reduces burst size (a fitness cost). How do these genes affect the net ecological fitness of the virus? Here, this question is explored using a combined systems biology and systems ecology ('systems bioecology') approach. A novel agent-based model simulates individual cyanobacteria cells and virus particles, each with their own genes, transcripts, proteins and other properties. The effect of D1 and HLIP proteins is explicitly considered using a mechanistic photosynthesis component. The model is calibrated to the available database for Prochlorococcus ecotype MED4 and podovirus P-SSP7. Laboratory- and field-scale in silico survival, competition and evolution (gene packaging error) experiments with wild type and genetically engineered viruses are performed to develop vertical survival and fitness profiles, and to determine the optimal gene content. The results suggest that photosynthesis genes are nonessential, increase fitness in a manner correlated with irradiance, and that the wild type has an optimal gene content.

  1. Report of mecC-carrying MRSA in domestic swine

    Science.gov (United States)

    Angen, Ø.; Stegger, M.; Larsen, J.; Lilje, B.; Kaya, H.; Pedersen, K. S.; Jakobsen, A.; Petersen, A.; Larsen, A. R.

    2017-01-01

    Objectives We unexpectedly identified MRSA isolates carrying mecC (mecC-MRSA) from a Danish swine farm located in eastern Zealand. The objective of the present study was to investigate the origin of these isolates and their genetic relatedness to other mecC-MRSA isolates from Zealand. Methods WGS was used to infer the phylogenetic relationship between 19 identified mecC-MRSA isolates from the swine farm and 34 additional epidemiologically unrelated human isolates from the same geographical region of Denmark. Variations in the accessory genome were investigated by bioinformatics tools, and antibiotic susceptibility profiles were assessed by MIC determination. Results mecC-MRSA was isolated from a domestic swine farm, but not from cattle reared at the same farm. Phylogenetic analysis revealed that all mecC-MRSA isolates from both farm animals and workers formed a separate cluster, whereas human isolates from the same municipality belonged to a closely related cluster. Analysis of the accessory genome supported this relationship. Conclusions To the best of our knowledge, this is the first report of mecC-MRSA isolated from domestic swine. The investigation strongly indicates that transmission of mecC-MRSA has taken place on the swine farm between the farmers and swine. The close clustering of farm isolates and isolates from the same municipality suggests a local transmission of mecC-MRSA. PMID:27650187

  2. Wildlife carrying capacities in relation to human settlement

    Directory of Open Access Journals (Sweden)

    S.K. Eltringham

    1990-09-01

    Full Text Available Human encroachment into wildlife areas, which has increased almost exponentially over the past few decades, has usually resulted in the elimination of the larger species, particularly the large mammals. This is not an inevitable consequence and this paper considers the extent to which man and wildlife can coexist. There is a linear inverse relationship between human and elephant densities and the reasons for this are discussed with particular reference to Uganda. Such a relationship does not necessarily hold for all species and the outcome of increasing human pressure on wildlife habitats varies with a variety of factors including the species concerned, the rainfall, vegetation, soil and, above all, the attitudes of the people towards wildlife. Wild animals are more likely to be tolerated if they do no harm to human activities or if the harm they do is outweighed by the benefits to be obtained from their exploitation. In many parts of Africa utilisation is likely to be the best hope for the conservation of wildlife. Some examples are given of situations in which worthwhile carrying capacities of wildlife can be maintained in the presence of human activities.

  3. Human embryonic stem cells carrying mutations for severe genetic disorders.

    Science.gov (United States)

    Frumkin, Tsvia; Malcov, Mira; Telias, Michael; Gold, Veronica; Schwartz, Tamar; Azem, Foad; Amit, Ami; Yaron, Yuval; Ben-Yosef, Dalit

    2010-04-01

    Human embryonic stem cells (HESCs) carrying specific mutations potentially provide a valuable tool for studying genetic disorders in humans. One preferable approach for obtaining these cell lines is by deriving them from affected preimplantation genetically diagnosed embryos. These unique cells are especially important for modeling human genetic disorders for which there are no adequate research models. They can be further used to gain new insights into developmentally regulated events that occur during human embryo development and that are responsible for the manifestation of genetically inherited disorders. They also have great value for the exploration of new therapeutic protocols, including gene-therapy-based treatments and disease-oriented drug screening and discovery. Here, we report the establishment of 15 different mutant human embryonic stem cell lines derived from genetically affected embryos, all donated by couples undergoing preimplantation genetic diagnosis in our in vitro fertilization unit. For further information regarding access to HESC lines from our repository, for research purposes, please email dalitb@tasmc.health.gov.il.

  4. Acoustic measurements above a plate carrying Lamb waves

    CERN Document Server

    Talberg, Andreas Sørbrøden

    2016-01-01

    This article presents a set of acoustic measurements conducted on the Statoil funded Behind Casing Logging Set-Up, designed by SINTEF Petroleum Research to resemble an oil well casing. A set of simple simulations using COMSOL Multiphysics were also conducted and the results compared with the measurements. The experiments consists of measuring the pressure wave radiated of a set of Lamb waves propagating in a 3 mm thick steel plate, using the so called pitch-catch method. The Lamb waves were excited by a broadband piezoelectric immersion transducer with center frequency of 1 MHz. Through measurements and analysis the group velocity of the fastest mode in the plate was found to be 3138.5 m/s. Measuring the wave radiated into the water in a grid consisting of 8x33 measuring points, the spreading of the plate wave normal to the direction of propagation was investigated. Comparing the point where the amplitude had decreased 50 % relative to the amplitude measured at the axis pointing straight forward from the tran...

  5. Limits for compression of quantum information carried by ensembles of mixed states

    CERN Document Server

    Horodecki, M

    1998-01-01

    We consider the problem of compression of the quantum information carried by ensemble of mixed states. We prove that for arbitrary coding schemes the least number of qubits needed to convey the signal states asymptotically faithfully is bounded from below by the Holevo function $S(\\varrho)-\\sum_ip_iS(\\varrho_i)$. We also show that a compression protocol can be composed with another one, provided that the latter offers perfect transmission. Such a compound protocol is applied to the case of binary source. It is conjectured to reach the obtained bound. Finally, we point out that in the case of mixed signal states there could be a difference between the maximal compression rates at the coding schemes which are ``blind'' to the signal and the ones which assume the knowledge about the identities of the signal states.

  6. Case study

    DEFF Research Database (Denmark)

    Milana, Marcella; Bernt Sørensen, Tore

    that time Roskilde University Centre and Learning Lab Denmark, DK)3. The case here presented is based on results from research activity carried out over a 1 year period (spring 2006 - spring 2007). Detailed information concerning participation in the project was collected in two DHSs only: the Sports Day...

  7. Inverse PCR for subtyping of Acinetobacter baumannii carrying ISAba1.

    Science.gov (United States)

    Kim, Shukho; Park, Yun-Ju; Kim, Jungmin

    2016-05-01

    Acinetobacter baumannii has been prevalent in nosocomial infections, often causing outbreaks in intensive care units. ISAba1 is an insertion sequence that has been identified only in A. baumannii and its copy number varies among strains. It has been reported that ISAba1 provides a promoter for bla(OXA-51-like), bla(OXA-23-like), and bla(ampC), which are associated with the resistance of A. baumannii to carbapenems and cephalosporins. The main purpose of this study was to develop a novel inverse PCR method capable of typing A. baumannii strains. The method involves three major steps: cutting of genomic DNA with a restriction enzyme, ligation, and PCR. In the first step, bacterial genomic DNA was digested with DpnI. In the second step, the digested genomic DNAs were ligated to form intramolecular circular DNAs. In the last step, the ligated circular DNAs were amplified by PCR with primers specific for ISAba1 and the amplified PCR products were electrophoresed. Twenty-two clinical isolates of A. baumannii were used for the evaluation of the inverse PCR (iPCR) typing method. Dendrogram analysis revealed two major clusters, similar to pulsed-field gel electrophoresis (PFGE) results. Three ISAba1-associated genes--bla(ampC), bla(OXA-66-like), and csuD--were amplified and detected in the clinical isolates. This novel iPCR typing method is comparable to PFGE in its ability to discriminate A. baumannii strains, and is a promising molecular epidemiological tool for investigating A. baumannii carrying ISAba1.

  8. Roadmap and performance carried out during Ciemat site decommissioning

    Energy Technology Data Exchange (ETDEWEB)

    Quinones, Javier; Diaz Diaz, Jose Luis

    2005-01-01

    Ciemat (Research Centre for Energy, Environment and Technology) located in the heart of the Ciudad Universitaria of Madrid, occupies a property of 20 Ha. Since its creation in 1951 as JEN, and in 1986 renowned as Ciemat, it has involved on R and D projects in the field of Energy and Environment, i.e., Nuclear Fission, Nuclear Fusion, Fossils Fuels, Renewable Energy. As a consequence of the R and D projects developed between 1951 - 1986 on Nuclear Fission field (fuel design, fabrication, characterization on irradiated fuels, safety studies, etc) and to the diversification of the goals as well, it is necessary to Decommissioning and Dismantling (D and D) from nuclear facilities (nuclear reactor, Hot Cells, Irradiation facility), buildings and soils. Preparations for D and D included a staged shutdown of operations, planning documentation and licensing for decommissioning. As a prerequisite to Ciemat application for a decommissioning license and nuclear environmental assessment was carried out according to Spanish Nuclear Council (CSN) and approval of the site decommissioning project was obtained in 2000 and valid until December 31, 2006. Since 2001 - 2003 is underway and focussed on the radiological characterization of the site (divided in pieces of ground), when each piece of ground is characterized a planning for D and D is presented to CSN in order to obtain a license for actuation. Nowadays several pieces of ground are decontaminated and modifications have been done in order to achieve a safe state of storage-with-surveillance. Later phases have planned waste management improvements for selected wastes already on temporally storage, eventually followed by final decommissioning of facilities and buildings and cleaning of contaminants from soils and removal of waste from the site. This paper describes the planning, nuclear and environment assessment and descriptions of decommissioning activities currently underway at Ciemat. (Author)

  9. Is Learning in Low Immersive Environments Carried over to High Immersive Environments?

    Directory of Open Access Journals (Sweden)

    Dror David Lev

    2012-01-01

    Full Text Available One of the more debated issues regarding training simulators is their validity for transfer of skills to sensory environments that differ from the simulator. In two experiments, the advantages of three-dimensional (3D and collocated (Col visual displays were evaluated in a realistic and complex visuomotor task. The two factors were evaluated independently, comparing Col-2D with dislocated-2D (experiment 1 and with Col-3D (experiment 2. As expected, in both cases the more immersive presentation condition facilitated better performance. Furthermore, improvement following training in the more immersive condition carried over to the following less immersive condition but there was no carry over in the opposing order of presentation. This is taken as an indication for the differential development of skills conditioned by the level of immersiveness of the training environment. This further suggests that learning of complex realistic tasks is not carried over from less immersive simulator to the complex sensory environment of reality, due to the large gap in sensory patterns.

  10. On evolutionary stability of carrying capacity driven dispersal in competition with regularly diffusing populations.

    Science.gov (United States)

    Korobenko, L; Braverman, E

    2014-11-01

    Two competing populations in spatially heterogeneous but temporarily constant environment are investigated: one is subject to regular movements to lower density areas (random diffusion) while the dispersal of the other is in the direction of the highest per capita available resources (carrying capacity driven diffusion). The growth of both species is subject to the same general growth law which involves Gilpin-Ayala, Gompertz and some other equations as particular cases. The growth rate, carrying capacity and dispersal rate are the same for both population types, the only difference is the dispersal strategy. The main result of the paper is that the two species cannot coexist (unless the environment is spatially homogeneous), and the carrying capacity driven diffusion strategy is evolutionarily stable in the sense that the species adopting this strategy cannot be invaded by randomly diffusing population. Moreover, once the invasive species inhabits some open nonempty domain, it would spread over any available area bringing the native species diffusing randomly to extinction. One of the important technical results used in the proofs can be interpreted in the form that the limit solution of the equation with a regular diffusion leads to lower total population fitness than the ideal free distribution.

  11. Measurement and assessment of carrying capacity of the environment in Ningbo, China.

    Science.gov (United States)

    Liu, R Z; Borthwick, Alistair G L

    2011-08-01

    Carrying Capacity of the Environment (CCE) provides a useful measure of the sustainable development of a region. Approaches that use integrated assessment instead of measurement can lead to misinterpretation of sustainable development because of confusion between Environmental Stress (ES) indexes and CCE indexes, and the selection of over-simple linear plus models. The present paper proposes a comprehensive measurement system for CCE which comprises models of natural resources capacity, environmental assimilative capacity, ecosystem services capacity, and society supporting capacity. The corresponding measurable indexes are designed to assess CCE using a carrying capacity surplus ratio model and a vector of surplus ratio of carrying capacity model. The former aims at direct comparison of ES and CCE based on the values of basic indexes, and the latter uses a Euclidean vector to assess CCE states. The measurement and assessment approaches are applicable to Strategic Environmental Assessment (SEA) and environmental planning and management. A case study is presented for Ningbo, China, whereby all the basic indexes of ECC are measured and the CCE states assessed for 2005 and 2010.

  12. Estimating landscape carrying capacity through maximum clique analysis.

    Science.gov (United States)

    Donovan, Therese M; Warrington, Gregory S; Schwenk, W Scott; Dinitz, Jeffrey H

    2012-12-01

    Habitat suitability (HS) maps are widely used tools in wildlife science and establish a link between wildlife populations and landscape pattern. Although HS maps spatially depict the distribution of optimal resources for a species, they do not reveal the population size a landscape is capable of supporting--information that is often crucial for decision makers and managers. We used a new approach, "maximum clique analysis," to demonstrate how HS maps for territorial species can be used to estimate the carrying capacity, N(k), of a given landscape. We estimated the N(k) of Ovenbirds (Seiurus aurocapillus) and bobcats (Lynx rufus) in an 1153-km2 study area in Vermont, USA. These two species were selected to highlight different approaches in building an HS map as well as computational challenges that can arise in a maximum clique analysis. We derived 30-m2 HS maps for each species via occupancy modeling (Ovenbird) and by resource utilization modeling (bobcats). For each species, we then identified all pixel locations on the map (points) that had sufficient resources in the surrounding area to maintain a home range (termed a "pseudo-home range"). These locations were converted to a mathematical graph, where any two points were linked if two pseudo-home ranges could exist on the landscape without violating territory boundaries. We used the program Cliquer to find the maximum clique of each graph. The resulting estimates of N(k) = 236 Ovenbirds and N(k) = 42 female bobcats were sensitive to different assumptions and model inputs. Estimates of N(k) via alternative, ad hoc methods were 1.4 to > 30 times greater than the maximum clique estimate, suggesting that the alternative results may be upwardly biased. The maximum clique analysis was computationally intensive but could handle problems with < 1500 total pseudo-home ranges (points). Given present computational constraints, it is best suited for species that occur in clustered distributions (where the problem can be

  13. Program's method of VB to carry out nuclear data collection The VB is stated for Visual Basic

    CERN Document Server

    Zhao Yan Hui; Zou Qi Hong; Xu Yin

    2002-01-01

    The authors expatiate Program's methods of VB to carry out nuclear data collection in the case of that VB can not directly call on hardware, and had to using C or assemble language to compile DLL function of call on hardware, and then, using by VB main routine to realize to call on and control I/O port in VB environment

  14. Carrying capacity in arid rangelands during droughts: the role of temporal and spatial thresholds.

    Science.gov (United States)

    Accatino, F; Ward, D; Wiegand, K; De Michele, C

    2017-02-01

    Assessing the carrying capacity is of primary importance in arid rangelands. This becomes even more important during droughts, when rangelands exhibit non-equilibrium dynamics, and the dynamics of livestock conditions and forage resource are decoupled. Carrying capacity is usually conceived as an equilibrium concept, that is, the consumer density that can co-exist in long-term equilibrium with the resource. As one of the first, here we address the concept of carrying capacity in systems, where there is no feedback between consumer and resource in a limited period of time. To this end, we developed an individual-based model describing the basic characteristics of a rangeland during a drought. The model represents a rangeland composed by a single water point and forage distributed all around, with livestock units moving from water to forage and vice versa, for eating and drinking. For each livestock unit we implemented an energy balance and we accounted for the gut-filling effect (i.e. only a limited amount of forage can be ingested per unit time). Our results showed that there is a temporal threshold above which livestock begin to experience energy deficit and burn fat reserves. We demonstrated that such a temporal threshold increases with the number of animals and decreases with the rangeland conditions (amount of forage). The temporal threshold corresponded to the time livestock take to consume all the forage within a certain distance from water, so that the livestock can return to water for drinking without spending more energy than they gain within a day. In this study, we highlight the importance of a time threshold in the assessment of carrying capacity in non-equilibrium conditions. Considering this time threshold could explain contrasting observations about the influence of livestock number on livestock conditions. In case of private rangelands, the herd size should be chosen so that the spatial threshold equals (or exceeds) the length of the drought.

  15. [Advance euthanasia directives in dementia rarely carried out. Qualitative study in physicians and patients].

    Science.gov (United States)

    Rurup, Mette L; Pasman, H R W Roeline; Onwuteaka-Philipsen, Bregje D

    2010-01-01

    To study how advance euthanasia directives (AEDs) in dementia are viewed in practice in the Netherlands. Qualitative study. In-depth interviews on nine patients with the patients themselves and/or partners and their physicians. The patients were included from a cohort of people with an AED. All interviews were done in 2006. Cases were included with different diagnoses and at different stages of dementia. Interviewed patients and their relatives had very high expectations of the feasibility of the AED. Interviewed physicians often thought of AEDs as aids in starting up a dialogue about medical decisions at the end of life, but they did not always do this in practice. Most physicians were open to adhering to AEDs in exceptional cases, on condition that the patient obviously suffered, and that communication with the patient to some extent was possible. In this study two cases were found in which adhering to the AED was seriously considered. In one case, fear of legal consequences was the only reason the physician had not adhered to the AED, while it seemed all the requirements of due care could be met. Euthanasia was not carried out in the other patient either. Several physicians mentioned the need for more detailed practical guidelines for the use of AEDs for dementia. Patients had too high expectations of AEDs. It seemed that in exceptional cases the requirements for due care for euthanasia can be met in patients with dementia with an AED. It seems advisable that more detailed practical guidelines for the use of AEDs in cases of dementia be drawn up, as a first step to more clarity for patients and physicians.

  16. Tensorial spacetime geometries carrying predictive, interpretable and quantizable matter dynamics

    Energy Technology Data Exchange (ETDEWEB)

    Rivera Hernandez, Sergio

    2012-02-15

    Which tensor fields G on a smooth manifold M can serve as a spacetime structure? In the first part of this thesis, it is found that only a severely restricted class of tensor fields can provide classical spacetime geometries, namely those that can carry predictive, interpretable and quantizable matter dynamics. The obvious dependence of this characterization of admissible tensorial spacetime geometries on specific matter is not a weakness, but rather presents an insight: it was Maxwell theory that justified Einstein to promote Lorentzian manifolds to the status of a spacetime geometry. Any matter that does not mimick the structure of Maxwell theory, will force us to choose another geometry on which the matter dynamics of interest are predictive, interpretable and quantizable. These three physical conditions on matter impose three corresponding algebraic conditions on the totally symmetric contravariant coefficient tensor field P that determines the principal symbol of the matter field equations in terms of the geometric tensor G: the tensor field P must be hyperbolic, time-orientable and energy-distinguishing. Remarkably, these physically necessary conditions on the geometry are mathematically already sufficient to realize all kinematical constructions familiar from Lorentzian geometry, for precisely the same structural reasons. This we were able to show employing a subtle interplay of convex analysis, the theory of partial differential equations and real algebraic geometry. In the second part of this thesis, we then explore general properties of any hyperbolic, time-orientable and energy-distinguishing tensorial geometry. Physically most important are the construction of freely falling non-rotating laboratories, the appearance of admissible modified dispersion relations to particular observers, and the identification of a mechanism that explains why massive particles that are faster than some massless particles can radiate off energy until they are slower than all

  17. Hutchinson-Gilford progeria syndrome as a model for vascular aging.

    Science.gov (United States)

    Brassard, Jonathan A; Fekete, Natalie; Garnier, Alain; Hoesli, Corinne A

    2016-02-01

    Hutchinson-Gilford progeria syndrome (HGPS) is a premature aging disorder caused by a de novo genetic mutation that leads to the accumulation of a splicing isoform of lamin A termed progerin. Progerin expression alters the organization of the nuclear lamina and chromatin. The life expectancy of HGPS patients is severely reduced due to critical cardiovascular defects. Progerin also accumulates in an age-dependent manner in the vascular cells of adults that do not carry genetic mutations associated with HGPS. The molecular mechanisms that lead to vascular dysfunction in HGPS may therefore also play a role in vascular aging. The vascular phenotypic and molecular changes observed in HGPS are strikingly similar to those seen with age, including increased senescence, altered mechanotransduction and stem cell exhaustion. This article discusses the similarities and differences between age-dependent and HGPS-related vascular aging to highlight the relevance of HGPS as a model for vascular aging. Induced pluripotent stem cells derived from HGPS patients are suggested as an attractive model to study vascular aging in order to develop novel approaches to treat cardiovascular disease.

  18. A Turner Syndrome Patient Carrying a Mosaic Distal X Chromosome Marker

    Science.gov (United States)

    Mazzaschi, Roberto L. P.; Taylor, Juliet; Robertson, Stephen P.; Love, Donald R.; George, Alice M.

    2014-01-01

    A skin sample from a 17-year-old female was received for routine karyotyping with a set of clinical features including clonic seizures, cardiomyopathy, hepatic adenomas, and skeletal dysplasia. Conventional karyotyping revealed a mosaic Turner syndrome karyotype with a cell line containing a small marker of X chromosome origin. This was later confirmed on peripheral blood cultures by conventional G-banding, fluorescence in situ hybridisation and microarray analysis. Similar Turner mosaic marker chromosome cases have been previously reported in the literature, with a variable phenotype ranging from the mild “classic” Turner syndrome to anencephaly, agenesis of the corpus callosum, complex heart malformation, and syndactyly of the fingers and toes. This case report has a phenotype that is largely discordant with previously published cases as it lies at the severe end of the Turner variant phenotype scale. The observed cytogenetic abnormalities in this study may represent a coincidental finding, but we cannot exclude the possibility that the marker has a nonfunctioning X chromosome inactivation locus, leading to functional disomy of those genes carried by the marker. PMID:24778889

  19. A Turner Syndrome Patient Carrying a Mosaic Distal X Chromosome Marker

    Directory of Open Access Journals (Sweden)

    Roberto L. P. Mazzaschi

    2014-01-01

    Full Text Available A skin sample from a 17-year-old female was received for routine karyotyping with a set of clinical features including clonic seizures, cardiomyopathy, hepatic adenomas, and skeletal dysplasia. Conventional karyotyping revealed a mosaic Turner syndrome karyotype with a cell line containing a small marker of X chromosome origin. This was later confirmed on peripheral blood cultures by conventional G-banding, fluorescence in situ hybridisation and microarray analysis. Similar Turner mosaic marker chromosome cases have been previously reported in the literature, with a variable phenotype ranging from the mild “classic” Turner syndrome to anencephaly, agenesis of the corpus callosum, complex heart malformation, and syndactyly of the fingers and toes. This case report has a phenotype that is largely discordant with previously published cases as it lies at the severe end of the Turner variant phenotype scale. The observed cytogenetic abnormalities in this study may represent a coincidental finding, but we cannot exclude the possibility that the marker has a nonfunctioning X chromosome inactivation locus, leading to functional disomy of those genes carried by the marker.

  20. NEW APPROACHES FOR COMPUTING DYNAMIC LOAD-CARRYING CAPACITY OF MULTIPLE COOPERATING ROBOTIC MANIPULATORS

    Institute of Scientific and Technical Information of China (English)

    1998-01-01

    A novel unified method for computing the dynamic load-carrying capacity(DLCC) of multiple cooperating robotic manipulators is developed.In this method,the kinematic constraints and the governing dynamic equations of the multiple robot system are formulated in the joint space by using the method of transference of dependence from one set of generalized coordinates to another,and the virtual work principle,which includes the readily available dynamics and joint torques of individual manipulators,and the dynamic of payload.Based on this dynamic model,the upper limit of the DLCC at any points on a given trajectory is obtained by solving a small-size linear programming problem.This method is conceptually straightforward,and it is applicable also to the cases of multi-fingered robot hands and multi-legged walking machines.

  1. Noise-Induced Transitions in a Population Growth Model Based on Size-Dependent Carrying Capacity

    Directory of Open Access Journals (Sweden)

    Neeme Lumi

    2014-01-01

    Full Text Available The stochastic dynamics of a population growth model with size-dependent carrying capacity is considered. The effect of a fluctuating environment on population growth is modeled as a multiplicative dichotomous noise. At intermediate values of population size the deterministic counterpart of the model behaves similarly to the Von Foerster model for human population, but at small and very large values of population size substantial differences occur. In the stochastic case, an exact analytical solution for the stationary probability distribution is found. It is established that variation of noise correlation time can cause noise-induced transitions between three different states of the system characterized by qualitatively different behaviors of the probability distributions of the population size. Also, it is shown that, in some regions of the system parameters, variation of the amplitude of environmental fluctuations can induce single unidirectional abrupt transitions of the mean population size.

  2. On the locality of parallel transport of heat carrying electrons in the SOL

    Energy Technology Data Exchange (ETDEWEB)

    Chankin, A.V., E-mail: Alex.Chankin@ipp.mpg.de; Coster, D.P.

    2015-08-15

    A continuum Vlasov–Fokker–Planck code KIPP is used to assess the degree of locality of parallel transport of heat carrying electrons (HCE) in collisional SOLs. It is shown that for typical SOL collisionalities, the HCE are marginally collisionless which puts into question successful parameterization of kinetic code results of transport parameters such as parallel heat flux and ion–electron thermoforce in the present 2D fluid codes. A kinetic solution for the case of 90% recycling at the target and factor 10T{sub e} drop along the field line is also presented, showing the degree of heat flux ‘limiting’ upstream and ‘enhancement’ downstream, compared to predictions of the Braginskii’s (or Spitzer–Härm’s) formulas. Possible causes of these features are discussed.

  3. Antenna Gain and Link Budget for Waves Carrying Orbital Angular Momentum (OAM)

    CERN Document Server

    Nguyen, Duy Kevin; Sokoloff, Jérôme; Chabory, Alexandre; Palacin, Baptiste; Capet, Nicolas

    2015-01-01

    This paper addresses the RF link budget of a communication system using unusual waves carrying an orbital angular momentum (OAM) in order to clearly analyse the fundamental changes for telecommunication applications. The study is based on a typical configuration using circular array antennas to transmit and receive OAM waves. For any value of the OAM mode order, an original asymptotic formulation of the link budget is proposed in which equivalent antenna gains and free-space losses appear. The formulations are then validated with the results of a commercial electromagnetic simulation software. By this way, we also show how our formula can help to design a system capable of superimposing several channels on the same bandwidth and the same polarisation, based on the orthogonality of the OAM. Additional losses due to the use of this degree of freedom are notably clearly calculated to quantify the benefit and drawback according to the case.

  4. Correlates of weapon carrying in school among adolescents in three countries.

    Science.gov (United States)

    Stickley, Andrew; Koyanagi, Ai; Koposov, Roman; Blatný, Marek; Hrdlička, Michal; Schwab-Stone, Mary; Ruchkin, Vladislav

    2015-01-01

    To determine the factors associated with weapon carrying in school among Czech, Russian, and US adolescents. Logistic regression was used to analyze data drawn from the Social and Health Assessment (SAHA). Violent behavior (perpetration / victimization) was linked to adolescent weapon carrying in all countries. Substance use was associated with weapon carrying among boys in all countries. Greater parental warmth reduced the odds for weapon carrying among Czech and Russian adolescents. Associating with delinquent peers was important for weapon carrying only among US adolescents. Factors associated with weapon carrying in school vary among countries although violent behavior and substance use may be associated with weapon carrying across countries.

  5. 基于组间进位预测的快速进位加法器%Rapid Carry Adder Based on Carry Forecast Between Groups

    Institute of Scientific and Technical Information of China (English)

    丁宜栋; 刘昌明; 方湘艳

    2011-01-01

    为加快密码系统中大数加法的运算速度,提出并实现一种基于组间进位预测的快速进位加法器.将参与加法运算的大数进行分组,每个分组采用改进的超前进位技术以减少组内进位延时,组间通过进位预测完成不同进位状态下的加法运算,通过每个组产生的进位状态判断最终结果.性能分析表明,该进位加法器实现1024位大数加法运算的速度较快.%This paper presents and realizes a rapid carry adder based on carry forecast between groups to improve the speed of the large numbers adder in some cryptography systems. The large numbers is divided into many groups, the delay of carry-chain is reduced by carry lookahead in group. The group addition operation of different carry state is finished by carry forecast between groups. The addition sun of different carry forecast state is selected as the final result based on the carry state. Performance analysis shows that the computing speed of the carry adder is faster when realizing the 1 024 bit large numbers add operation.

  6. Dynamic Carrying Capacity Analysis of Double-Row Four-Point Contact Ball Slewing Bearing

    OpenAIRE

    Yunfeng Li; Di Jiang

    2015-01-01

    Carrying capacity is the most important performance index for slewing bearings. Maximizing the carrying capacity of slewing bearing is one pursuing goal for the bearing designer; this is usually realized by optimizing the design parameters. A method of analyzing the carrying capacity of double-row four-point contact ball slewing bearing by using dynamic carrying capacity surfaces was proposed in this paper. Based on the dynamic load carrying capacity surface of the slewing bearing, the effect...

  7. Thermal shaft effects on load-carrying capacity of a fully coupled, variable-properties cryogenic journal bearing

    Science.gov (United States)

    Braun, M. J.; Wheeler, R. L., III; Hendricks, R. C.

    1986-01-01

    The purpose of this work was to perform a rather complete analysis for a cryogenic (oxygen) journal bearing. The Reynolds equation required coupling and simultaneous solution with the fluid energy equation. To correctly account for the changes in the fluid viscosity, the fluid energy equation was coupled with the shaft and bearing heat conduction energy equations. The effects of pressure and temperature on the density, viscosity, and load-carrying capacity were further discussed as analysis parameters, with respect to relative eccentricity and the angular velocity. The isothermal fluid case and the adiabatic fluid case represented the limiting boundaries. The discussion was further extrapolated to study the Sommerfeld number dependency on the fluid Nusselt number and its consequence on possible total loss of load-carrying capacity and/or seizure (catastrophic failure).

  8. Overlap syndrome between FMF and TRAPS in a patient carrying MEFV and TNFRSF1A mutations.

    Science.gov (United States)

    Granel, B; Serratrice, J; Dodé, C; Grateau, G; Disdier, P; Weiller, P-J

    2007-01-01

    Familial Mediterranean Fever (FMF) and TNF-Receptor Associated Periodic Syndrome (TRAPS) are two inheritable inflammatory disorders. They share some clinical manifestations but their treatments are different. We present here the case of an overlap syndrome of FMF and TRAPS in a patient carrying a mutation in both the MEFV and TNFRSF1A genes. A 20-year-old woman of Mediterranean origin had suffered since childhood from attacks of fever and arthritis, with skin and ophthalmic manifestations. The initial diagnosis was FMF. The symptoms responded poorly to colchicine but regressed with steroids. Genetic analysis revealed a homozygous M694V mutation in MEFV and a heterozygous R92Q mutation in TNFRSF1A. We discuss the complexity of this combined FMF-TRAPS phenotype. This case shows that mutations in MEFV and TNFRSF1A can occur together in a single patient, a condition that may modify its response to treatment. It would be interesting to evaluate the role of the R92Q mutation in TNFRSF1A in patients of Mediterranean origin with FMF unresponsive to colchicine.

  9. Detection of mcr-1-Carrying Escherichia coli Causing Bloodstream Infection in a New York City Hospital: Avian Origins, Human Concerns?

    Science.gov (United States)

    Macesic, Nenad; Green, Daniel; Wang, Zheng; Sullivan, Sean B; Shim, Kevin; Park, Sarah; Whittier, Susan; Furuya, E Yoko; Gomez-Simmonds, Angela; Uhlemann, Anne-Catrin

    2017-01-01

    The spread of mcr-1 in the United States remains poorly defined. mcr-1-producing Escherichia coli that also carried blaSHV-12 was detected in a hospitalized patient. No additional cases were identified during screening of 801 Gram-negative isolates. Genomic sequencing identified an IncX4 mcr-1- harboring plasmid and ST117 clonal background associated with avian pathogenic E coli.

  10. Evaluation of Carrying Capacity Land-Based Layout to Mitigate Flood Risk (Case Study in Tempuran Floodplain, Ponorogo Regency) Novia Lusiana1 Bambang Rahadi2 Tunggul Sutanhaji3 1Environmental and Natural Resources Management Graduate Program University of Brawijaya, Malang, Indonesia 23Laboratory of Environment and Natural Resources Engineering, Department of Agricultural Engineering, Faculty of Agricultural Technology, University of Brawijaya, Malang, Indonesia Email : novialusiana@rocketmail.com, jbrahadi@ub.ac.id, tunggulsutanhaji@yahoo.com

    Science.gov (United States)

    Lusiana, N.

    2013-12-01

    Abstract Floods haves frequently hit Indonesia and have had greater negative impacts. In Javaboth the area affected by flooding and the amount of damage caused by floods have increased. At least, five factors, affect the flooding in Indonesia, including rainfall, reduced retention capacity of the watershed, erroneous design of river channel development, silting-up of the river, and erroneous regional layout. The level of the disastrous risks can be evaluated based on the extent of the threat and susceptibility of a region. One methode for risk assessment is Geographical Information System (GIS)-based mapping. Objectives of this research are: 1) evaluating current flood risk in susceptible areas, 2) applying supported land-based layout as effort to mitigate floodrisk, and 3) evaluating floodrisk for the period 2031 in the Tempuran floodplain of Ponorogo Regency. Result show that the area categorized as high risk covers 104. 6 ha (1. 2%), moderate risk covers 2512. 9 ha (28. 4%), low risk covers 3140. 8 ha (35. 5%), and the lowest risk covers 3096. 1 (34. 9%). Using Regional Layout Design for the years 2011 - 2031, the high risk area covers 67. 9 ha (0.8%), moderate risk covers 3033 ha (34. 3%), low risk covers 2770. 8 ha (31, 3%), and the lowest risk covers 2982. 6 ha (34%). Based on supported land suitability, the high-risk areais only 2. 9 ha (0.1%), moderate risk covers of 426. 1 ha (4. 8%), low risk covers 4207. 4 ha (47. 5%), and the lowest risk covers 4218 ha (47. 6%). Flood risk can be mitigated by applying supported land-based layout as shown by the reduced high-risk area, and the fact that > 90% of the areas are categorized as low or lowest risk of disaster. Keywords : Carrying Capacity, Land Capacity, Flood Risk

  11. [Ecotourism carrying capacity of Hangzhou Xixi National Wetland Park in China].

    Science.gov (United States)

    Li, Rui; Rong, Liang

    2007-10-01

    In this paper, an integrated estimation on the ecotourism carrying capacity of Hangzhou Xixi National Wetland Park in China was made from the aspects of ecological carrying capacity, spatial carrying capacity, facility carrying capacity, management carrying capacity, and psychological carrying capacity. The results indicated that the tourism carrying capacity of the Park was 4 145 - 6 450 persons per day. The rational distance between man and bird was first adopted to determine the ecotourism carrying capacity of wetland, which provided an effective solution both to fully ensure bird safety and to appropriately develop wetland tourism. The estimation of psychological carrying capacity based on tourist satisfaction degree reflected more objectively the extent the tourist demands satisfied at the planning, construction and management of tour places. Such an integrated estimation method based on the distance between man and bird and the tourist satisfaction degree could be of practical and instructive significances in the planning and management of wetland parks.

  12. Proceedings of the Third International Workshop on Proof-Carrying Code and Software Certification

    Science.gov (United States)

    Ewen, Denney, W. (Editor); Jensen, Thomas (Editor)

    2009-01-01

    This NASA conference publication contains the proceedings of the Third International Workshop on Proof-Carrying Code and Software Certification, held as part of LICS in Los Angeles, CA, USA, on August 15, 2009. Software certification demonstrates the reliability, safety, or security of software systems in such a way that it can be checked by an independent authority with minimal trust in the techniques and tools used in the certification process itself. It can build on existing validation and verification (V&V) techniques but introduces the notion of explicit software certificates, Vvilich contain all the information necessary for an independent assessment of the demonstrated properties. One such example is proof-carrying code (PCC) which is an important and distinctive approach to enhancing trust in programs. It provides a practical framework for independent assurance of program behavior; especially where source code is not available, or the code author and user are unknown to each other. The workshop wiII address theoretical foundations of logic-based software certification as well as practical examples and work on alternative application domains. Here "certificate" is construed broadly, to include not just mathematical derivations and proofs but also safety and assurance cases, or any fonnal evidence that supports the semantic analysis of programs: that is, evidence about an intrinsic property of code and its behaviour that can be independently checked by any user, intermediary, or third party. These guarantees mean that software certificates raise trust in the code itself, distinct from and complementary to any existing trust in the creator of the code, the process used to produce it, or its distributor. In addition to the contributed talks, the workshop featured two invited talks, by Kelly Hayhurst and Andrew Appel. The PCC 2009 website can be found at http://ti.arc.nasa.gov /event/pcc 091.

  13. Weapon carrying and psychopathic-like features in a population-based sample of Finnish adolescents.

    Science.gov (United States)

    Saukkonen, Suvi; Laajasalo, Taina; Jokela, Markus; Kivivuori, Janne; Salmi, Venla; Aronen, Eeva T

    2016-02-01

    We investigated the prevalence of juvenile weapon carrying and psychosocial and personality-related risk factors for carrying different types of weapons in a nationally representative, population-based sample of Finnish adolescents. Specifically, we aimed to investigate psychopathic-like personality features as a risk factor for weapon carrying. The participants were 15-16-year-old adolescents from the Finnish self-report delinquency study (n = 4855). Four different groups were formed based on self-reported weapon carrying: no weapon carrying, carrying knife, gun or other weapon. The associations between psychosocial factors, psychopathic-like features and weapon carrying were examined with multinomial logistic regression analysis. 9% of the participants had carried a weapon in the past 12 months. Adolescents with a history of delinquency, victimization and antisocial friends were more likely to carry weapons in general; however, delinquency and victimization were most strongly related to gun carrying, while perceived peer delinquency (antisocial friends) was most strongly related to carrying a knife. Better academic performance was associated with a reduced likelihood of carrying a gun and knife, while feeling secure correlated with a reduced likelihood of gun carrying only. Psychopathic-like features were related to a higher likelihood of weapon carrying, even after adjusting for other risk factors. The findings of the study suggest that adolescents carrying a weapon have a large cluster of problems in their lives, which may vary based on the type of weapon carried. Furthermore, psychopathic-like features strongly relate to a higher risk of carrying a weapon.

  14. Psychophysical determination of load carrying capacity for a 1-h work period by Chinese males.

    Science.gov (United States)

    Wu, S P; Chen, C C

    2001-09-15

    This study used the psychophysical approach to examine the effects of container width, the presence or absence of container handles, and different load-carrying frequencies and distances on the maximum acceptable weight carried and the resulting response (heart rate and rating of perceived exertion) by well-conditioned males for a 1-h work period. After training, 12 male subjects performed a load-carrying task at knuckle height. Each subject performed 30 different carrying combinations. The conditions examined were container width, from 15.2 to 55.9 cm; carrying frequency, from 1 carry to 5 carries/min; and carrying distance from 1 to 6 m. The results were compared with prior studies and led to the following conclusions: (1) the use of container handles leads to the subjects carrying a significantly higher maximum acceptable weight than when containers do not have handles, which differs from the results of a previous study by Morrissey and Liou; (2) there were significant reductions in the maximum acceptable carrying weight with increases in container width, frequency and distance; (3) the presence or absence of container handles, different frequencies and load-carrying distances had significant effects on heart rate, although the effect of container width was not significant. In addition, the various frequencies and distances for load carrying had significant interaction effects on heart rate; (4) the effects of various frequencies and load-carrying distances on the rating of perceived exertion were statistically significant. The most stressed body parts were the wrists and arms.

  15. Sdelki carry trade ne roskosh, a sredstvo nakoplenija / Darius Gecevicius, Dmitri Fokin

    Index Scriptorium Estoniae

    Gecevicius, Darius

    2007-01-01

    Strateegia carry trade kasutamisest valuutaturgudel. Carry trade on tehing, mis enamasti toimub valuutaturul, kus investor laenab raha sisse valuutas, mille intressid on madalamad ning paigutab selle valuutas, kus intressid on kõrgemad. Diagramm

  16. Sdelki carry trade ne roskosh, a sredstvo nakoplenija / Darius Gecevicius, Dmitri Fokin

    Index Scriptorium Estoniae

    Gecevicius, Darius

    2007-01-01

    Strateegia carry trade kasutamisest valuutaturgudel. Carry trade on tehing, mis enamasti toimub valuutaturul, kus investor laenab raha sisse valuutas, mille intressid on madalamad ning paigutab selle valuutas, kus intressid on kõrgemad. Diagramm

  17. Strengthening Carrying Capacity of a Water Supply System under Climate Change with the Drought Early Warning System

    Science.gov (United States)

    Huang, Syujie; Liu, Tzuming; Li, Minghsu; Tung, Chingpin

    2016-04-01

    The carrying capacity of a water supply system is the maximal probable water supply amount under an acceptable risk which is related to the systematic combination of hydrology conditions, climatic conditions, and water infrastructures, for instance, reservoirs, weirs, and water treatment plants. Due to long-term imbalance of water supply and demand during the drought seasons, the carrying capacity of a water supply system may be affected gradually with more extreme climate events resulting from the climate change. To evaluate the carrying capacity of the water supply system under climate change, three major steps to build adaptation capacity under climate change are adopted, including problem identification and goal setting, current risk assessment, and future risk assessment. The carrying capacities for current climate condition and future climate condition were estimated respectively. The early warning system was taken as the effective measure to strengthen the carrying capacity for the uncertain changing climate. The water supply system of Chuoshui River basin in Taiwan is used as the case study. The system dynamics modeling software, Vensim, was used to build the water resources allocation model for Chuoshui River basin. To apply the seasonal climate forecasts released from Taiwan Central Weather Bureau (CWB) on modeling, a weather generator is adopted to generate daily weather data for the input of the hydrological component of GWLF model, to project inflows with the lead time of three months. Consequently, the water shortages with and without a drought early warning system were estimated to evaluate the effectiveness of a drought early warning system under climate change. Keywords: Climate change, Carrying capacity, Risk Assessment, Seasonal Climate Forecasts, Drought Early Warning System

  18. A tabu-search for minimising the carry-over effects value of a round-robin tournament

    Directory of Open Access Journals (Sweden)

    MP Kidd

    2010-12-01

    Full Text Available A player b in a round-robin sports tournament receives a carry-over effect from another player a if some third player opposes a in round i and b in round i+1. Let γ(ab denote the number of times player b receives a carry-over effect from player a during a tournament. Then the carry-over effects value of the entire tournament T on n players is given by Γ(T=ΣΣγ(ij^2. Furthermore, let Γ(n denote the minimum carry-over effects value over all round-robin tournaments on n players. A strict lower bound on Γ(n is n(n-1 (in which case there exists a round-robin tournament of order n such that each player receives a carry-over effect from each other player exactly once, and it is known that this bound is attained for n=2^r or n=20,22. It is also known that round-robin tournaments can be constructed from so-called starters; round-robin tournaments constructed in this way are called cyclic. It has previously been shown that cyclic round-robin tournaments have the potential of admitting small values for Γ(T, and in this paper a tabu-search is used to find starters which produce cyclic tournaments with small carry-over effects values. The best solutions in the literature are matched for n<=22, and new upper bounds are established on Γ(n for 24<=n<=40.

  19. 46 CFR 180.72 - Personal flotation devices carried in addition to life jackets.

    Science.gov (United States)

    2010-10-01

    ... Jackets § 180.72 Personal flotation devices carried in addition to life jackets. (a) Equipment carried... jackets and must not be substituted for the approved life jackets required to be worn during drills and... 46 Shipping 7 2010-10-01 2010-10-01 false Personal flotation devices carried in addition to life...

  20. 36 CFR 1005.4 - Commercial passenger-carrying motor vehicles.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Commercial passenger-carrying motor vehicles. 1005.4 Section 1005.4 Parks, Forests, and Public Property PRESIDIO TRUST COMMERCIAL AND PRIVATE OPERATIONS § 1005.4 Commercial passenger-carrying motor vehicles. Passenger-carrying...

  1. 49 CFR 395.3 - Maximum driving time for property-carrying vehicles.

    Science.gov (United States)

    2010-10-01

    ... used by it to drive a property-carrying commercial motor vehicle, nor shall any such driver drive a property-carrying commercial motor vehicle: (1) More than 11 cumulative hours following 10 consecutive... commercial motor vehicle to drive, nor shall any driver drive a property-carrying commercial motor...

  2. Campaign for Right to Carry Concealed Guns on Campuses Gains Traction

    Science.gov (United States)

    Wiseman, Rachel

    2012-01-01

    Five years after the Virginia Tech massacre prompted a student in Texas to start a Facebook page in favor of the right to carry concealed weapons on college campuses, the resulting group, Students for Concealed Carry, has advanced its cause. In more than a dozen states, legislation has been introduced to allow the carrying of concealed firearms on…

  3. 46 CFR 150.160 - Carrying a cargo as an exception to the compatibility chart.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Carrying a cargo as an exception to the compatibility... BULK DANGEROUS CARGOES COMPATIBILITY OF CARGOES § 150.160 Carrying a cargo as an exception to the compatibility chart. The Operator of a vessel having on board a cargo carried as an exception under §...

  4. 25 CFR 161.204 - How are carrying capacities and stocking rates established?

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false How are carrying capacities and stocking rates... WATER NAVAJO PARTITIONED LANDS GRAZING PERMITS General Provisions § 161.204 How are carrying capacities..., review and adjust the carrying capacity of each range unit by determining the number of livestock,...

  5. In vitro pathological modelling using patient-specific induced pluripotent stem cells: the case of progeria.

    Science.gov (United States)

    Nissan, Xavier; Blondel, Sophie; Peschanski, Marc

    2011-12-01

    Progeria, also known as HGPS (Hutchinson-Gilford progeria syndrome), is a rare fatal genetic disease characterized by an appearance of accelerated aging in children. This syndrome is typically caused by mutations in codon 608 (C1804T) of the gene encoding lamins A and C, LMNA, leading to the production of a truncated form of the protein called progerin. Owing to their unique potential to self-renew and to differentiate into any cell types of the organism, pluripotent stem cells offer a unique tool to study molecular and cellular mechanisms related to this global and systemic disease. Recent studies have exploited this potential by generating human induced pluripotent stem cells from HGPS patients' fibroblasts displaying several phenotypic defects characteristic of HGPS such as nuclear abnormalities, progerin expression, altered DNA-repair mechanisms and premature senescence. Altogether, these findings provide new insights on the use of pluripotent stem cells for pathological modelling and may open original therapeutic perspectives for diseases that lack pre-clinical in vitro human models, such as HGPS.

  6. Design of High-Speed Hybrid Carry Select Adders using VHDL

    OpenAIRE

    Mr. Vijay V. Gotmare; Dr. Pankaj Agarwal

    2016-01-01

    Carry select adder (CSA) is a square-root time high-speed adder. CSA is one of the fastest adders used in many data processing systems to perform fast arithmetic operations. In this project we propose to design hybrid carry select adders with a focus on high speed. CSA is a compromise between the longer delay Ripple carry adder (RCA) and the shorter delay Carry look-ahead adder (CLA). Conventionally carry select adders are realize using the full adders and 2:1 multiplexers. On the other hand ...

  7. Temperature dependences of growth rates and carrying capacities of marine bacteria depart from metabolic theoretical predictions

    KAUST Repository

    Huete-Stauffer, Tamara Megan

    2015-09-11

    Using the metabolic theory of ecology (MTE) framework, we evaluated over a whole annual cycle the monthly responses to temperature of the growth rates (μ) and carrying capacities (K) of heterotrophic bacterioplankton at a temperate coastal site. We used experimental incubations spanning 6oC with bacterial physiological groups identified by flow cytometry according to membrane integrity (live), nucleic acid content (HNA and LNA) and respiratory activity (CTC+). The temperature dependence of μat the exponential phase of growth was summarized by the activation energy (E), which was variable (-0.52 to 0.72 eV) but followed a seasonal pattern, only reaching the hypothesized value for aerobic heterotrophs of 0.65 eV during the spring bloom for the most active bacterial groups (live, HNA, CTC+). K (i.e. maximum experimental abundance) peaked at 4 × 106 cells mL-1 and generally covaried with μbut, contrary to MTE predictions, it did not decrease consistently with temperature. In the case of live cells, the responses of μand K to temperature were positively correlated and related to seasonal changes in substrate availability, indicating that the responses of bacteria to warming are far from homogeneous and poorly explained by MTE at our site. © FEMS 2015.

  8. Achromobacter xylosoxidans: an emerging pathogen carrying different elements involved in horizontal genetic transfer.

    Science.gov (United States)

    Traglia, German Matías; Almuzara, Marisa; Merkier, Andrea Karina; Adams, Christina; Galanternik, Laura; Vay, Carlos; Centrón, Daniela; Ramírez, María Soledad

    2012-12-01

    In the last few years, numerous cases of multidrug-resistant Achromobacter xylosoxidans infections have been documented in immunocompromised and cystic fibrosis patients. To gain insights into the molecular mechanisms and mobile elements related to multidrug resistance in this bacterium, we studied 24 non-epidemiological A. xylosoxidans clinical isolates from Argentina. Specific primers for plasmids, transposons, insertion sequences, bla(ampC), intI1, and intI2 genes were used in PCR reactions. The obtained results showed the presence of wide host range IncP plasmids in ten isolates and a high dispersion of class 1 integrons (n = 10) and class 2 integrons (n = 3). Four arrays in the variable region (vr) of class 1 integrons were identified carrying different gene cassettes as the aminoglycoside resistance aac(6')-Ib and aadA1, the trimethoprim resistance dfrA1 and dfrA16, and the β-lactamase bla(OXA-2). In only one of the class 2 integrons, a vr was amplified that includes sat2-aadA1. The bla(ampC) gene was found in all isolates, confirming its ubiquitous nature. Our results show that A. xylosoxidans clinical isolates contain a rich variety of genetic elements commonly associated with resistance genes and their dissemination. This supports the hypothesis that A. xylosoxidans is becoming a reservoir of horizontal genetic transfer elements commonly involved in spreading antibiotic resistance.

  9. (ANTI)PETER Principle - Discrete (INVERSE) Logistic Equation with Imprecisely Estimated and Stimulated Carrying Capacity

    CERN Document Server

    Pankovic, V; Glavatovic, R

    2009-01-01

    In this work we consider the Peter principle and anti-Peter principle as the discrete logistic and discrete inverse logistic equation. Especially we discuss imprecisely estimated (by hierarchical control mechanism) carrying capacity, i.e. boundary (in)competence level of a hierarchy member. It implies that Peter principle holds two sub-principles. In the first one objective boundary competence level is increased for estimation error. In the second one objective boundary competence level is decreased for estimation error. Similarly, anti-Peter principle holds two sub-principles too. All this implies that paradoxical situations that follow from Peter and anti-Peter principle can be simply removed by decrease of the error of hierarchical (social) control. Also we discuss cases by Peter principle when error of the boundary competence level by estimation grows up. (Then, in fact, there is no estimation error but stimulation of the boundary level by control mechanism.) By first Peter sub-principle it implies anarch...

  10. The energetic costs of load-carrying and the evolution of bipedalism.

    Science.gov (United States)

    Watson, J C; Payne, R C; Chamberlain, A T; Jones, R K; Sellers, W I

    2008-05-01

    The evolution of habitual bipedalism is still a fundamental yet unsolved question for paleoanthropologists, and carrying is popular as an explanation for both the early adoption of upright walking and as a positive selection pressure once a terrestrial lifestyle had been adopted. However, to support or reject any hypothesis that suggests carrying efficiency was an important selective pressure, we need quantitative data on the costs of different forms of carrying behavior, especially infant-carrying since reduction in the grasping capabilities of the foot would have prevented infants from clinging on for long durations. In this study, we tested the hypothesis that the mode of load carriage influences the energetic cost of locomotion. Oxygen consumption was measured in seven female participants walking at a constant speed while carrying four different 10-kg loads (a weighted vest, 5-kg dumbbells carried in each hand, a mannequin infant carried on one hip, and a 10-kg dumbbell carried in a single hand). Oxygen consumption was also measured during unloaded standing and unloaded walking. The results show that the weighted vest requires the least amount of energy of the four types of carrying and that, for this condition, humans are as efficient as mammals in general. The balanced load was carried with approximately the predicted energy cost. However, the asymmetrical conditions were considerably less efficient, indicating that, unless infant-carrying was the adaptive response to a strong environmental selection pressure, this behavior is unlikely to have been the precursor to the evolution of bipedalism.

  11. Dynamic Carrying Capacity Analysis of Double-Row Four-Point Contact Ball Slewing Bearing

    Directory of Open Access Journals (Sweden)

    Yunfeng Li

    2015-01-01

    Full Text Available Carrying capacity is the most important performance index for slewing bearings. Maximizing the carrying capacity of slewing bearing is one pursuing goal for the bearing designer; this is usually realized by optimizing the design parameters. A method of analyzing the carrying capacity of double-row four-point contact ball slewing bearing by using dynamic carrying capacity surfaces was proposed in this paper. Based on the dynamic load carrying capacity surface of the slewing bearing, the effect of changes of the bearing design parameters, such as axial clearance, raceway groove radius coefficient, and contact angle, on the dynamic carrying capacity of the slewing bearing was researched; the trend and the degree of the effect of the micro changes of the bearing design parameters on the dynamic load carrying capacity of the bearing were discussed, and the results provide the basis for optimizing the design parameter of this type of slewing bearing.

  12. Naïve adult stem cells from patients with Hutchinson-Gilford progeria syndrome express low levels of progerin in vivo

    Science.gov (United States)

    Wenzel, Vera; Roedl, Daniela; Gabriel, Diana; Gordon, Leslie B.; Herlyn, Meenhard; Schneider, Reinhard; Ring, Johannes; Djabali, Karima

    2012-01-01

    Summary Hutchinson-Gilford progeria syndrome (HGPS, OMIM 176670) is a rare disorder characterized by segmental accelerated aging and early death from coronary artery disease or stroke. Nearly 90% of HGPS sufferers carry a G608G mutation within exon 11 of LMNA, producing a truncated form of prelamin A, referred to as “progerin”. Here, we report the isolation of naïve multipotent skin-derived precursor (SKP) cells from dermal fibroblast cultures from HGPS donors. These cells form spheres and express the neural crest marker, nestin, in addition to the multipotent markers, OCT4, Sox2, Nanog and TG30; these cells can self-renew and differentiate into smooth muscle cells (SMCs) and fibroblasts. The SMCs derived from the HGPS-SKPs accumulate nuclear progerin with increasing passages. A subset of the HGPS-naïve SKPs express progerin in vitro and in situ in HGPS skin sections. This is the first in vivo evidence that progerin is produced in adult stem cells, and implies that this protein could induce stem cells exhaustion as a mechanism contributing to aging. Our study provides a basis on which to explore therapeutic applications for HGPS stem cells and opens avenues for investigating the pathogenesis of other genetic diseases. PMID:23213444

  13. Naïve adult stem cells from patients with Hutchinson-Gilford progeria syndrome express low levels of progerin in vivo

    Directory of Open Access Journals (Sweden)

    Vera Wenzel

    2012-04-01

    Hutchinson-Gilford progeria syndrome (HGPS, OMIM 176670 is a rare disorder characterized by segmental accelerated aging and early death from coronary artery disease or stroke. Nearly 90% of HGPS sufferers carry a G608G mutation within exon 11 of LMNA, producing a truncated form of prelamin A, referred to as “progerin”. Here, we report the isolation of naïve multipotent skin-derived precursor (SKP cells from dermal fibroblast cultures from HGPS donors. These cells form spheres and express the neural crest marker, nestin, in addition to the multipotent markers, OCT4, Sox2, Nanog and TG30; these cells can self-renew and differentiate into smooth muscle cells (SMCs and fibroblasts. The SMCs derived from the HGPS-SKPs accumulate nuclear progerin with increasing passages. A subset of the HGPS-naïve SKPs express progerin in vitro and in situ in HGPS skin sections. This is the first in vivo evidence that progerin is produced in adult stem cells, and implies that this protein could induce stem cells exhaustion as a mechanism contributing to aging. Our study provides a basis on which to explore therapeutic applications for HGPS stem cells and opens avenues for investigating the pathogenesis of other genetic diseases.

  14. STUDY OF CARRYING CAPACITY OF A CORRUGATED METAL CONSTRUCTION BY CRITERION OF YIELD HINGE DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    Y. Y. Luchko

    2015-10-01

    Full Text Available Purpose. This research is aimed to: 1 calculation of equivalent forces caused by rolling stock in winter and summer seasons at different parameters of the irregularities of railway track; 2 research of bearing capacity of corrugated metal constructions (CMC in terms of development of plastic hinge in the top of the metal pipe due to irreversible residual deformation of the vertical and horizontal diameters of the pipe. Methodology. The calculation of equivalent forces is carried out according to the method of calculating the railway track on strength and stability. Further a mathematical algorithm was developed in the software environment of Mathcad 14, with which the calculations were made about the formation of a plastic hinge at the top of the pipe for different values of the irregularities of the railway track and the degree of compaction of soil backfill. In these studies, the calculations were carried out at the design value of the compaction degree of soil backfill and magnitude of dynamic loading on railway rolling stock. Findings. Analysis of multivariate calculations of testing the condition of occurrence of plastic hinge at the top of the pipe arch has revealed that the first plastic hinge, which occurs in the set of CMC is revealed only when there is a simultaneous unfavorable influence of two factors (causes. These are the factors: the assumption of the development of the track irregularities out of the allowable values without the implementation of measures to eliminate or limit the speed of trains (the first cause; reduction of compaction of soil backfill below the 90 % (the second cause. In case of absence of one of the causes the origin of the plastic hinge will not happen. Originality. It was the first time, when the bearing capacity of corrugated metal construction with large diameter (more than 6 m with account of factors complex: the degree of compaction of soil backfill, the magnitude of the dynamic loads from rolling stock

  15. A model to estimate aquaculture carrying capacity in three areas of the Philippines

    Directory of Open Access Journals (Sweden)

    Tarzan Legović

    2008-12-01

    Full Text Available A model was developed to estimate the production carrying capacity of water bodies based on nutrient inputs from aquaculture and other sources, flushing rates, and the risk of algal blooms for three different areas of the Philippines – Bolinao (marine site, Dagupan (brackishwater site and Taal Lake (freshwater site. The results suggest that aquaculture production in the Taal Lake was greater than the sustainable carrying capacity. Aquaculture structures in Bolinao were close to carrying capacity during average tidal exchange but greater than the carrying capacity during low tidal exchange and no winds.Aquaculture production in the Dagupan estuary has not overcome its carrying capacity even during low flow. However, during very low flow and no tidal flushing, carrying capacity has been overcome.

  16. Design & Analysis of Low Power, Area-Efficient Carry Select Adder

    Directory of Open Access Journals (Sweden)

    Shuchi Verma

    2014-03-01

    Full Text Available This paper deals with the design & analysis of Carry Select Adder (CSLA & Carry lookahead adder (CLA. Adders are designed using 0.18µm CMOS process technology & simulated with Modelsim6.3f. The adder designs, Regular CSLA, modified CSLA using BEC, modified CSLA without using multiplexer, modified CSLA using D-Latch & Carry lookahead adders in 4-bit, 16-bit, 32-bit, are compared with the simulated results on the basis area.

  17. Synchronisation of fertility with carrying capacity; an investigation using classical and agent based modeling

    Directory of Open Access Journals (Sweden)

    Hugh Crozier Murrell

    2013-05-01

    Full Text Available A generalized Verhulst model subject to seasonal change in both fertility rate and carrying capacity is outlined. Numerical solutions to the Verhulst equations are employed to obtain optimal fertility rate phase shift with respect to carrying capacity. Possible natural selection for a preferred season of conception is investigated using agent based simulations. Both experiments indicate that synchronization of fertility rate to environment carrying capacity is beneficial to species survival.

  18. Research on Carrying Capacity of Water Resource Based on Multi-reservoir Regulation

    OpenAIRE

    Liu Renyuan; Li Lei; Li Hua; Huang Qiang

    2013-01-01

    Analyze the level of Carrying Capacity of Water Resources; evaluate the condition of e region social, economic and ecological environment comprehensive and sustainable development. This study is based on analyzing the meaning of water resources carrying capacity, take water resources of the Midwest of Shenzhen City an example., by the way of the “Coordinated and sustainable development” theory, found the model of the Carrying Capacity of Water Resources, Calculated and analyzed. Water efficie...

  19. Effects of a Fluctuating Carrying Capacity on the Generalized Malthus-Verhulst Model

    OpenAIRE

    Héctor Calisto; Chandía, Kristopher J.; Mauro Bologna

    2014-01-01

    We consider a generalized Malthus-Verhulst model with a fluctuating carrying capacity and we study its effects on population growth. The carrying capacity fluctuations are described by a Poissonian process with an exponential correlation function. We will find an analytical expression for the average of a number of individuals and show that even in presence of a fluctuating carrying capacity the average tends asymptotically to a constant quantity.

  20. Estimating Recreational Carrying Capacity of Gheisary Protected Area in Chaharmahal & Bakhtiari Province

    OpenAIRE

    Sheikh, A; Jafari, A.; Setoodeh, A

    2014-01-01

    It is now certain that to ensure a long term sustainable development, protected areas, the favored destinations for ecotourism, required a well written planning management. Each destination however has limited capability which is called “carrying capacity” to invite visitors. Physical, real (ecological) and effective (manageable) are different kinds of carrying capacity. The current study presented these varieties of carrying capacities for Gheisary protected area, stretched over 10,000 ha in...

  1. ANALYSIS OF ABILITY FOR IGNITING METHANE OF WATER-CARRYING EXPLOSIVES

    Institute of Scientific and Technical Information of China (English)

    陆守香

    1997-01-01

    In this paper, the ability to ignite methane of water-carrying explosives is discussed in detail. The difference of the safety towards methane of water- carrying explosives and ammonite is analysed comparatively. It is shown that the process of detonation reaction, the duration of flame by combustible residues of detonation and the fineness of cooling salt in detonation products are important factors of the safety of explosive towards methane. Water-carrying explosives are safer than ammonite used in coal mines.

  2. Effects of a Fluctuating Carrying Capacity on the Generalized Malthus-Verhulst Model

    Directory of Open Access Journals (Sweden)

    Héctor Calisto

    2014-01-01

    Full Text Available We consider a generalized Malthus-Verhulst model with a fluctuating carrying capacity and we study its effects on population growth. The carrying capacity fluctuations are described by a Poissonian process with an exponential correlation function. We will find an analytical expression for the average of a number of individuals and show that even in presence of a fluctuating carrying capacity the average tends asymptotically to a constant quantity.

  3. The Association Between Weapon Carrying and Health Risk Behaviors Among Adolescent Students in Bangkok, Thailand.

    Science.gov (United States)

    Saiphoklang, On-Anong; Wongboonsin, Kua; Wongboonsin, Patcharawalai; Perngparn, Usaneya; Cottler, Linda B

    2015-07-30

    Carrying weapons is a significant social and public health problem worldwide, especially among adolescents. The present study examined the association between weapon carrying and related risk behaviors among Thai adolescents. A cross-sectional study of 2,588 high school and vocational school students aged 11 to 19 years from 26 schools in Bangkok, Thailand, was conducted in 2014. This study found that 7.8% of youth reported having carried a weapon in the past 12 months. The high prevalence of weapon carrying was reported by male students, and males were more likely to have reported carrying a weapon than females. The association between weapon carrying and the health risk behaviors like drinking, smoking, any drug use, and physical fighting were significant with higher odds of weapon carrying in all models. Among males, weapon carrying was related to drinking and smoking, any drug use, physical fighting, and school type. Among females, suicidal thoughts were significantly related along with drinking and smoking, any drug use, and physical fighting. Having a mother who used substances was significant only among females. These data could be used for further interventions about weapon carrying to reduce violence. © The Author(s) 2015.

  4. Review on the Evaluation System of Public Safety Carrying Capacity about Small Town Community

    Institute of Scientific and Technical Information of China (English)

    Ming; SUN; Tianyu; ZHU

    2014-01-01

    Recently,small town community public safety problem has been increasingly highlighted,but its research is short on public safety carrying capacity. Through the investigation and study of community public safety carrying capacity,this paper analyzes the problem of community public safety in our country,to construct index evaluation system of public safety carrying capacity in small town community. DEA method is used to evaluate public safety carrying capacity in small town community,to provide scientific basis for the design of support and standardization theory about small town community in public safety planning.

  5. An Area-Efficient Carry Select Adder Design by using 180 nm Technology

    OpenAIRE

    Garish Kumar Wadhwa; Amit Grover; Neeti Grover; GurpreetSingh

    2013-01-01

    In this paper, we proposed an area-efficient carry select adder by sharing the common Boolean logic term. After logic simplification and sharing partial circuit, we only need one XOR gate and one inverter gate in each summation operation as well as one AND gate and one inverter gate in each carry-out operation. Through the multiplexer, we can select the correct output result according to the logic state of carry-in signal. In this way, the transistor count in a 32-bit carry select adder can b...

  6. An Area-Efficient Carry Select Adder Design by using 180 nm Technology

    Directory of Open Access Journals (Sweden)

    Garish Kumar Wadhwa

    2013-02-01

    Full Text Available In this paper, we proposed an area-efficient carry select adder by sharing the common Boolean logic term. After logic simplification and sharing partial circuit, we only need one XOR gate and one inverter gate in each summation operation as well as one AND gate and one inverter gate in each carry-out operation. Through the multiplexer, we can select the correct output result according to the logic state of carry-in signal. In this way, the transistor count in a 32-bit carry select adder can be greatly reduced from 1947 to 960.

  7. Specifying the Role of Exposure to Violence and Violent Behavior on Initiation of Gun Carrying: A Longitudinal Test of Three Models of Youth Gun Carrying

    Science.gov (United States)

    Spano, Richard; Pridemore, William Alex; Bolland, John

    2012-01-01

    Two waves of longitudinal data from 1,049 African American youth living in extreme poverty are used to examine the impact of exposure to violence (Time 1) and violent behavior (Time 1) on first time gun carrying (Time 2). Multivariate logistic regression results indicate that (a) violent behavior (Time 1) increased the likelihood of initiation of…

  8. Specifying the Role of Exposure to Violence and Violent Behavior on Initiation of Gun Carrying: A Longitudinal Test of Three Models of Youth Gun Carrying

    Science.gov (United States)

    Spano, Richard; Pridemore, William Alex; Bolland, John

    2012-01-01

    Two waves of longitudinal data from 1,049 African American youth living in extreme poverty are used to examine the impact of exposure to violence (Time 1) and violent behavior (Time 1) on first time gun carrying (Time 2). Multivariate logistic regression results indicate that (a) violent behavior (Time 1) increased the likelihood of initiation of…

  9. Carrying-out of Simple Civil Case%论简易程序民事案件的执行

    Institute of Scientific and Technical Information of China (English)

    田世元; 陈福君

    2001-01-01

    司法公正是时代潮流,我国早在一九九六年便在机构上确立了"审执分立"作为一种制度也不可避免地存在其弊端,本文将就此加以论述,以最大地实现人民法院公正与效率的主题.

  10. Understanding Where Americas Public Discussion Takes Place In Todays Society: Case Studies of Concealed Weapons Carry Reform

    Science.gov (United States)

    2016-06-01

    priorities and views. Stuart Hall , in describing his encoding-decoding framework, theorizes that while media encodes certain messages, the audience decodes...04/17/despite-lower-crime-rates-support-for-gun-rights-increases/. 20 Stuart Hall , “Encoding/Decoding,” in Media and Cultural Studies: Keyworks, 2nd...interviewed the two students who stopped the shooter with personal firearms, 21 Stuart Hall , “Encoding/Decoding

  11. Estimating a Global Hydrological Carrying Capacity Using GRACE Observed Water Stress

    Science.gov (United States)

    An, K.; Reager, J. T.; Famiglietti, J. S.

    2013-12-01

    Global population is expected to reach 9 billion people by the year 2050, causing increased demands for water and potential threats to human security. This study attempts to frame the overpopulation problem through a hydrological resources lens by hypothesizing that observed groundwater trends should be directly attributed to human water consumption. This study analyzes the relationships between available blue water, population, and cropland area on a global scale. Using satellite data from NASA's Gravity Recovery and Climate Experiment (GRACE) along with land surface model data from the Global Land Data Assimilation System (GLDAS), a global groundwater depletion trend is isolated, the validity of which has been verified in many regional studies. By using the inherent distributions of these relationships, we estimate the regional populations that have exceeded their local hydrological carrying capacity. Globally, these populations sum to ~3.5 billion people that are living in presently water-stressed or potentially water-scarce regions, and we estimate total cropland is exceeding a sustainable threshold by about 80 million km^2. Key study areas such as the North China Plain, northwest India, and Mexico City were qualitatively chosen for further analysis of regional water resources and policies, based on our distributions of water stress. These case studies are used to verify the groundwater level changes seen in the GRACE trend . Tfor the many populous, arid regions of the world that have already begun to experience the strains of high water demand.he many populous, arid regions of the world have already begun to experience the strains of high water demand. It will take a global cooperative effort of improving domestic and agricultural use efficiency, and summoning a political will to prioritize environmental issues to adapt to a thirstier planet. Global Groundwater Depletion Trend (Mar 2003-Dec 2011)

  12. Hutchinson-Gilford Progeria Syndrome: A Rare Genetic Disorder

    Science.gov (United States)

    Panigrahi, Rajat G.; Panigrahi, Antarmayee; Vijayakumar, Poornima; Choudhury, Priyadarshini; Bhuyan, Sanat K.; Bhuyan, Ruchi; Maragathavalli, G.; Pati, Abhishek Ranjan

    2013-01-01

    Hutchinson-Gilford progeria syndrome (HGPS) is a rare pediatric genetic syndrome with incidence of one per eight million live births. The disorder is characterised by premature aging, generally leading to death at approximately 13.4 years of age. This is a follow-up study of a 9-year-old male with clinical and radiographic features highly suggestive of HGPS and presented here with description of differential diagnosis and dental consideration. This is the first case report of HGPS which showed pectus carinatum structure of chest. PMID:24288630

  13. Hutchinson-Gilford Progeria Syndrome: A Rare Genetic Disorder

    Directory of Open Access Journals (Sweden)

    Rajat G. Panigrahi

    2013-01-01

    Full Text Available Hutchinson-Gilford progeria syndrome (HGPS is a rare pediatric genetic syndrome with incidence of one per eight million live births. The disorder is characterised by premature aging, generally leading to death at approximately 13.4 years of age. This is a follow-up study of a 9-year-old male with clinical and radiographic features highly suggestive of HGPS and presented here with description of differential diagnosis and dental consideration. This is the first case report of HGPS which showed pectus carinatum structure of chest.

  14. Effect of initial stress on Love waves in a piezoelectric structure carrying a functionally graded material layer.

    Science.gov (United States)

    Qian, Zheng-Hua; Jin, Feng; Lu, Tianjian; Kishimoto, Kikuo; Hirose, Sohichi

    2010-01-01

    The effect of initial stress on the propagation behavior of Love waves in a piezoelectric half-space of polarized ceramics carrying a functionally graded material (FGM) layer is analytically investigated in this paper from the three-dimensional equations of linear piezoelectricity. The analytical solutions are obtained for the dispersion relations of Love wave propagating in this kind of structure with initial stress for both electrical open case and electrical short case, respectively. One numerical example is given to graphically illustrate the effect of initial stress on dispersive curve, phase velocity and electromechanical coupling factor of the Love wave propagation. The results reported here are meaningful for the design of surface acoustic wave (SAW) devices with high performance.

  15. Case study research.

    Science.gov (United States)

    Taylor, Ruth; Thomas-Gregory, Annette

    2015-06-10

    This article describes case study research for nursing and healthcare practice. Case study research offers the researcher an approach by which a phenomenon can be investigated from multiple perspectives within a bounded context, allowing the researcher to provide a 'thick' description of the phenomenon. Although case study research is a flexible approach for the investigation of complex nursing and healthcare issues, it has methodological challenges, often associated with the multiple methods used in individual studies. These are explored through examples of case study research carried out in practice and education settings. An overview of what constitutes 'good' case study research is proposed.

  16. 46 CFR 117.72 - Personal flotation devices carried in addition to life jackets.

    Science.gov (United States)

    2010-10-01

    ... PASSENGERS LIFESAVING EQUIPMENT AND ARRANGEMENTS Ring Life Buoys and Life Jackets § 117.72 Personal flotation devices carried in addition to life jackets. (a) Equipment carried under this section is not acceptable in lieu of any portion of the required number of approved life jackets and must not be substituted for the...

  17. Risk-premia, Carry-trade Dynamics, and Economic Value of Currency Speculation

    DEFF Research Database (Denmark)

    Wagner, Christian

    2012-01-01

    -cited ‘forward bias puzzle’ originates from the omission of the risk-premium in standard UIP tests. Consistent with its popularity among market professionals, the carry-trade strategy can be rationalized as it systematically collects risk-premia, however, the economic value generated by bilateral carry-trades...

  18. Form and Function of Carrying Tools in Traditional and Contemporary Culture

    Directory of Open Access Journals (Sweden)

    Hendriana Werdhaningsih

    2009-07-01

    Full Text Available The Javanese Traditional Carrying Tools are categorized into two kinds based used of materials: anyaman made of woven bamboo or rattan and the other was made of cloth. The Traditional Javanese Carrying Tools that were made of bamboo/ rattan is actually a kind of container with different shapes. The types of goods that were brought was related to the shapes of the containers, demonstrate the type of interactions between the carrier and the goods. The Traditional Carrying Tools made of cloth have the flexibility in terms of being the containers of the carried goods. Selendang is used to carry goods, including the bamboo/ rattan containers and to carry babies. It can be used rumpled and straightened depends on the technical needs of carrying tools preferred by the user. In contemporary culture, the form and design of carrying tools more less construct by fashion and trends besides those practical used. Some product are being 'classic', some other are being 'fad'. Both products, traditional and contemporary have their own style, uniqueness, and own context. Analyzing both in design point of view is important as evaluation process, to finding new problems that will be starting point to create new products. Indonesia is well known for its abundant richness in traditions, which include the culture, the art, and the traditional products. Such treasure of traditions can inspire the development and invention of various kinds of artwork and current products.

  19. Complete genome sequences of Incl1 Plasmids carrying extended-spectrum B-Lactamase genes

    NARCIS (Netherlands)

    Brouwer, M.S.M.; Bossers, A.; Harders, F.; Essen-Zandbergen, van A.; Mevius, D.J.; Smith, H.E.

    2014-01-01

    Extended spectrum beta-lactamases (ESBLs) confer resistance to clinically relevant antibiotics. Often, the resistance genes are carried by conjugative plasmids which are responsible for dissemination. Five IncI1 plasmids carrying ESBLs from commensal and clinical Escherichia coli isolates were compl

  20. Gun Cultures or Honor Cultures? Explaining Regional and Race Differences in Weapon Carrying

    Science.gov (United States)

    Felson, Richard B.; Pare, Paul-Philippe

    2010-01-01

    We use the National Violence against Women (and Men) Survey to examine the effects of region and race on the tendency to carry weapons for protection. We find that Southern and Western whites are much more likely than Northern whites to carry guns for self-protection, controlling for their risk of victimization. The difference between Southern and…

  1. Predictors of Weapon Carrying in Youth Attending Drop-in Centers

    Science.gov (United States)

    Blumberg, Elaine J.; Liles, Sandy; Kelley, Norma J.; Hovell, Melbourne F.; Bousman, Chad A.; Shillington, Audrey M.; Ji, Ming; Clapp, John

    2009-01-01

    Objective: To test and compare 2 predictive models of weapon carrying in youth (n=308) recruited from 4 drop-in centers in San Diego and Imperial counties. Methods: Both models were based on the Behavioral Ecological Model (BEM). Results: The first and second models significantly explained 39% and 53% of the variance in weapon carrying,…

  2. Carrying a Weapon to School and Perceptions of Social Support in an Urban Middle School.

    Science.gov (United States)

    Malecki, Christine Kerres; Demaray, Michelle Kilpatrick

    2003-01-01

    This study of perceived social support and weapon possession surveyed 461 students in an urban middle school. Students who reported carrying weapons to school reported less overall or total perceived social support (from peers, parents, teachers, classmates, and school) than did their peers who did not carry weapons. Perceived social support was a…

  3. Youths Carrying a Weapon or Using a Weapon in a Fight: What Makes the Difference?

    Science.gov (United States)

    Thurnherr, Judit; Michaud, Pierre-Andre; Berchtold, Andre; Akre, Christina; Suris, Joan-Carles

    2009-01-01

    The objective of this study was to characterize weapon-carrying adolescents and to assess whether weapon carriers differ from weapon users. Data were drawn from a cross-sectional school-based survey of 7548 adolescents aged 16-20 years in Switzerland. Youths carrying a weapon were compared with those who do not. Subsequently, weapon carriers were…

  4. Effect of Gun Carrying on Perceptions of Risk Among Adolescent Offenders.

    Science.gov (United States)

    Loughran, Thomas A; Reid, Joan A; Collins, Megan Eileen; Mulvey, Edward P

    2016-02-01

    We observed how perceptions of risks, costs, crime rewards, and violence exposure change as individual gun-carrying behavior changes among high-risk adolescents. We analyzed a longitudinal study (2000-2010) of serious juvenile offenders in Maricopa County, Arizona, or Philadelphia County, Pennsylvania, assessing within-person changes in risk and reward perceptions, and violence exposure as individuals initiated or ceased gun carrying. Despite being associated with heightened exposure to violence, gun carrying was linked to lower perceptions of risks and costs and higher perceived rewards of offending. Gun carrying was not time-stable, as certain individuals both started and stopped carrying during the study. Within-person changes in carrying guns were associated with shifting perceptions of risks, costs, and rewards of crime, and changes in exposure to violence in expected directions. Gun carrying reduces perceptions of risks associated with offending while increasing actual risk of violence exposure. This suggests that there is an important disconnect between perceptions and objective levels of safety among high-risk youths. Gun-carrying decisions may not only be influenced by factors of protection and self-defense, but also by perceptions of risks and reward associated with engaging in crime more generally.

  5. 48 CFR 19.707 - The Small Business Administration's role in carrying out the program.

    Science.gov (United States)

    2010-10-01

    ... Subcontracting Program 19.707 The Small Business Administration's role in carrying out the program. (a) Under the... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false The Small Business Administration's role in carrying out the program. 19.707 Section 19.707 Federal Acquisition Regulations...

  6. Gun Cultures or Honor Cultures? Explaining Regional and Race Differences in Weapon Carrying

    Science.gov (United States)

    Felson, Richard B.; Pare, Paul-Philippe

    2010-01-01

    We use the National Violence against Women (and Men) Survey to examine the effects of region and race on the tendency to carry weapons for protection. We find that Southern and Western whites are much more likely than Northern whites to carry guns for self-protection, controlling for their risk of victimization. The difference between Southern and…

  7. The application of a phosphorus mass balance model for estimating the carrying capacity of Lake Kariba

    OpenAIRE

    MHLANGA, Lindah; MHLANGA, Wilson; MWERA, Paul

    2013-01-01

    The aim of this study was to use an empirical mass balance equation to estimate the carrying capacity of Lake Kariba, where cage culture for Nile tilapia Oreochromis niloticus has been practiced since 1996. The carrying capacity for the lake was estimated at 33.2 × 103 t per year using the Dillon-Rigler phosphorus budget model.

  8. CERTAINTY EQUIVALENCE FOR DETERMINATION OF OPTIMAL FERTILIZER APPLICATION RATES WITH CARRY-OVER

    OpenAIRE

    Taylor, C. Robert

    1983-01-01

    This note demonstrates that a certain class of stochastic problems for determination of optimal fertilizer application rates in the presence of fertilizer carry-over can be simplified to static, certainly equivalent problems. Conditions required for certainty equivalence to hold are: (1) fertilizer carry-over is agronomically equivalent to applied fertilizer; and (2) some addition of fertilizer is optimal in every decision period.

  9. Toddlers actively reorganize their whole body coordination to maintain walking stability while carrying an object.

    Science.gov (United States)

    Hsu, Wen-Hao; Miranda, Daniel L; Chistolini, Trevor L; Goldfield, Eugene C

    2016-10-01

    Balanced walking involves freely swinging the limbs like pendula. However, children immediately begin to carry objects as soon as they can walk. One possibility for this early skill development is that whole body coordination during walking may be re-organized into loosely coupled collections of body parts, allowing children to use their arms to perform one function, while the legs perform another. Therefore, this study examines: 1) how carrying an object affects the coordination of the arms and legs during walking, and 2) if carrying an object influences stride length and width. Ten healthy toddlers with 3-12 months of walking experience were recruited to walk barefoot while carrying or not carrying a small toy. Stride length, width, speed, and continuous relative phase (CRP) of the hips and of the shoulders were compared between carrying conditions. While both arms and legs demonstrated destabilization and stabilization throughout the gait cycle, the arms showed a reduction in intra-subject coordination variability in response to carrying an object. Carrying an object may modify the function of the arms from swinging for balance to maintaining hold of an object. The observed period-dependent changes of the inter-limb coordination of the hips and of the shoulders also support this interpretation. Overall, these findings support the view that whole-body coordination patterns may become partitioned in particular ways as a function of task requirements.

  10. Phenomenological approach to describe logistic growth and carrying capacity-dependent growth processes

    Indian Academy of Sciences (India)

    DIBYENDU BISWAS; SWARUP PORIA; SANKAR NARAYAN PATRA

    2016-11-01

    In this communication, different classes of phenomenological universalities of carrying capacity dependent growth processes have been proposed. The logistic as well as carrying capacity-dependent West-type allometry-based biological growths can be explained in this proposed framework. It is shown that logistic and carrying capacity-dependent West-type growths are phenomenologically identical in nature. However, there is a difference between them in terms of coefficients involved in the phenomenological descriptions. Involuted Gompertz function, used to describe biological growth processes undergoing atrophy or a demographic and economic system undergoing involution or regression, can be addressed in this proposed environment-dependent description. It is also found phenomenologically that the energy intake of an organism depends on carrying capacity whereas metabolic cost does not depend on carrying capacity. In addition, some other phenomenologicaldescriptions have been examined in this proposed framework and graphical representations of variation of different parameters involved in the description are executed.

  11. A Feminist Reading of Sister Carrie: Carrie——the Aspiring Cinderella

    Institute of Scientific and Technical Information of China (English)

    殷娟

    2008-01-01

    Like Cinderella in the fairy tale Cinderella, Carrie is beautiful, innocent and poor. But unlike the traditional Cinderella who mindlessly waits around for a handsome prince to come to her rescue, Carrie, the aspiring Cinderella, resolvedly leaves the men she ever depended on and eventually becomes a successful actress. Sister Carrie, the most impressive heroine of Theodore Dreiser, is a contradictory character. Some accuse her of realizing her ambition with immoral means. However, some others take sympathy with her courage, determination, and aspiration. By analyzing the most distinguished quality of Sister Carrie - her aspiration, this essay is to illustrate from the perspective of feminism that women are not limited by their sex. Ignoring her own sex as well as the conventional attitude toward women in a male-dominated society, sister Carrie, full of aspiration, takes an active pan in creating and determining her own lives and her own futures..

  12. Research on Carrying Capacity of Water Resource Based on Multi-reservoir Regulation

    Directory of Open Access Journals (Sweden)

    Liu Renyuan

    2013-12-01

    Full Text Available Analyze the level of Carrying Capacity of Water Resources; evaluate the condition of e region social, economic and ecological environment comprehensive and sustainable development. This study is based on analyzing the meaning of water resources carrying capacity, take water resources of the Midwest of Shenzhen City an example., by the way of the “Coordinated and sustainable development” theory, found the model of the Carrying Capacity of Water Resources, Calculated and analyzed. Water efficiency coefficients are different in different states, the Carrying Capacity of Water Resources is different too. the water resources in the Midwest of Shenzhen City can only meet now this stage (2010 Urban water demand, meanwhile people of over loading in there are also constantly increasing, In the future, Water requirement of Shenzhen Midwest cities must increase Dongjiang water and west diversion works of Shen Zhen, in order to enhance Carrying Capacity of Water Resources of the area.

  13. Risk Analysis on Groundwater Resources Carrying Capacity Based on Blind Number Theory

    Institute of Scientific and Technical Information of China (English)

    ZHANG Ji; YU Sujun

    2007-01-01

    Blind numbers of evaluation indices about groundwater resources carrying capacity are defined from the concomitancy of randomness, fuzziness, grey property and unascertainment of groundwater system.Based on fuzzy theory, a comprehensive evaluation model on groundwaterresources carrying capacity is constructed with blind information. Then arisk assessment model of surcharge about groundwater resources carryingcapacity is established on blind reliability theory. The probable value"*"'matrix of fuzzy membership degree about carrying capacity corresponding to each judgment level can be obtained with the aid of blind algorithm as well as the subjective reliability "×" matrix. And then a graph of"groundwater carrying capacity v.s. accumulative reliability" can be gained.Based on the graph, fuzzy membership degree of groundwater resourcescarrying capacity to each judgment level under different risk probabilitycan be got. Thus, a comparatively reasonable judgment to groundwaterresources carrying capacity might be obtained, with comprehensive analysis to the state of society, economy technology and ecology.

  14. Comparative analysis of environmental carrying capacity of the Bohai Sea Rim area in China.

    Science.gov (United States)

    Lin, Lu; Liu, Yi; Chen, Jining; Zhang, Tianzhu; Zeng, Siyu

    2011-11-01

    Environmental carrying capacity is an essential metric for measuring regional sustainability. Although the term "carrying capacity" has been applied for over a century, the concept definition, quantitative methods and comprehensive evaluation remain arguable. This study analyzed the carrying capacity of four environmental elements, including water resources, air, surface water and offshore sea, and integrated them into a comprehensive index to represent overall regional profiles of resources and environment. The method was then applied to thirteen municipalities in the Bohai Sea Rim area, one of the most rapidly developing regions in transition China. The results show that the comprehensive environmental carrying capacity of the municipalities in the south sub-region were largest in 2007, while that of the west municipalities were lowest. The regional economic development exceeded the overall environmental carrying capacity by 36% and the west sub-region area deserves overwhelming attention for future industrial allocation.

  15. From Use Cases to Activity Cases

    DEFF Research Database (Denmark)

    Bækgaard, Lars

    2005-01-01

    Use cases can be used to capture requirements and to subdivide IT-systems into functionally coherent units. Information systems are activity systems that carry out important business activities. Many systems development methods recognize activity modeling as an important development activity. Use...

  16. Object carrying as socio-sexual display in an aquatic mammal.

    Science.gov (United States)

    Martin, A R; da Silva, V M F; Rothery, P

    2008-06-23

    Amazon river dolphins or botos (Inia geoffrensis Blainville) were observed carrying objects in 221 social groups over a 3-year study period. Sticks, branches and clumps of grass were taken from the water surface and often repeatedly thrashed or thrown. Lumps of hard clay were collected from the river bed and held in the mouth while the carrier rose slowly above the surface and submerged again. Carriers were predominantly adult males and less often subadult males. Adult females and young dolphins rarely carried objects. Groups of dolphins in which object carrying occurred were differentially large and comprised a greater proportion of adult males and adult females. Aggression, mostly between adult males, was significantly associated with object carrying. The behaviour occurred year-round, with peaks in March and July. A plausible explanation of the results is that object carrying by adult males is aimed at females and is stimulated by the number of females in the group, while aggression is targeted at adult males and is stimulated by object carrying in the group. We infer that object carrying in this sexually dimorphic species is socio-sexual display. It is either of ancient origin or has evolved independently in several geographically isolated populations.

  17. Ecological Carrying Capacity in Beijing Mountainous Areas Taking Fangshan District as an Example

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    [Objective] The aim was to investigate ecological carrying capacity of Fangshan District in Beijing. [Method] Ecological footprint and carrying capacity of Fangshan District in 2007 and 2008 were analyzed with ecological footprint model and the difference between ecological footprint and carrying capacity there was con- cluded. Furthermore, an assessment was made on relation between Fangshan de- velopment with local ecological carrying capacity to evaluate sustainable development of Fangshan District. [Result] Fangshan District is of lightly ecological deficit; ecologi- cal footprint per capita in 2007-2008 was deficit and tended to expand. Two meth- ods are available to reduce ecological :deficit, including reduction of ecological foot- print and increase of carrying capacity. In general, supply and demand of carrying capacity in Fangshan are better, though with some problems. It is necessary to fur- ther develop related industries to final eliminate ecological deficit in order to achieve ecological conservation-orientation and sustainable development of Fangshan District. [Conclusion] The research provides theoretical references for overall evaluation on eco- logical carrying capacity of Fangshan District.

  18. Physical and emotional health problems experienced by youth engaged in physical fighting and weapon carrying.

    Directory of Open Access Journals (Sweden)

    Sophie D Walsh

    Full Text Available Then aims of the current study were 1 to provide cross-national estimates of the prevalence of physical fighting and weapon carrying among adolescents aged 11-15 years; (2 To examine the possible effects of physical fighting and weapon carrying on the occurrence of physical (medically treated injuries and emotional health outcomes (multiple health complaints among adolescents within the theoretical framework of Problem Behaviour Theory. 20,125 adolescents aged 11-15 in five countries (Belgium, Israel, USA, Canada, FYR Macedonia were surveyed via the 2006 Health Behaviour in School Aged Children survey. Prevalence was calculated for physical fighting and weapon carrying along with physical and emotional measures that potentially result from violence. Regression analyses were used to quantify associations between violence/weapon carrying and the potential health consequences within each country. Large variations in fighting and weapon carrying were observed across countries. Boys reported more frequent episodes of fighting/weapon carrying and medically attended injuries in every country, while girls reported more emotional symptoms. Although there were some notable variations in findings between different participating countries, increased weapon carrying and physical fighting were both independently and consistently associated with more frequent reports of the potential health outcomes. Adolescents engaging in fighting and weapon carrying are also at risk for physical and emotional health outcomes. Involvement in fighting and weapon carrying can be seen as part of a constellation of risk behaviours with obvious health implications. Our findings also highlight the importance of the cultural context when examining the nature of violent behaviour for adolescents.

  19. Physical and emotional health problems experienced by youth engaged in physical fighting and weapon carrying.

    Science.gov (United States)

    Walsh, Sophie D; Molcho, Michal; Craig, Wendy; Harel-Fisch, Yossi; Huynh, Quynh; Kukaswadia, Atif; Aasvee, Katrin; Várnai, Dora; Ottova, Veronika; Ravens-Sieberer, Ulrike; Pickett, William

    2013-01-01

    Then aims of the current study were 1) to provide cross-national estimates of the prevalence of physical fighting and weapon carrying among adolescents aged 11-15 years; (2) To examine the possible effects of physical fighting and weapon carrying on the occurrence of physical (medically treated injuries) and emotional health outcomes (multiple health complaints) among adolescents within the theoretical framework of Problem Behaviour Theory. 20,125 adolescents aged 11-15 in five countries (Belgium, Israel, USA, Canada, FYR Macedonia) were surveyed via the 2006 Health Behaviour in School Aged Children survey. Prevalence was calculated for physical fighting and weapon carrying along with physical and emotional measures that potentially result from violence. Regression analyses were used to quantify associations between violence/weapon carrying and the potential health consequences within each country. Large variations in fighting and weapon carrying were observed across countries. Boys reported more frequent episodes of fighting/weapon carrying and medically attended injuries in every country, while girls reported more emotional symptoms. Although there were some notable variations in findings between different participating countries, increased weapon carrying and physical fighting were both independently and consistently associated with more frequent reports of the potential health outcomes. Adolescents engaging in fighting and weapon carrying are also at risk for physical and emotional health outcomes. Involvement in fighting and weapon carrying can be seen as part of a constellation of risk behaviours with obvious health implications. Our findings also highlight the importance of the cultural context when examining the nature of violent behaviour for adolescents.

  20. State Gun Law Environment and Youth Gun Carrying in the United States.

    Science.gov (United States)

    Xuan, Ziming; Hemenway, David

    2015-11-01

    Gun violence and injuries pose a substantial threat to children and youth in the United States. Existing evidence points to the need for interventions and policies for keeping guns out of the hands of children and youth. (1) To examine the association between state gun law environment and youth gun carrying in the United States, and (2) to determine whether adult gun ownership mediates this association. This was a repeated cross-sectional observational study design with 3 years of data on youth gun carrying from US states. The Youth Risk Behavior Survey comprises data of representative samples of students in grades 9 to 12 from biennial years of 2007, 2009, and 2011. We hypothesized that states with more restrictive gun laws have lower rates of youth gun carrying, and this association is mediated by adult gun ownership. State gun law environment as measured by state gun law score. Youth gun carrying was defined as having carried a gun on at least 1 day during the 30 days before the survey. In the fully adjusted model, a 10-point increase in the state gun law score, which represented a more restrictive gun law environment, was associated with a 9% decrease in the odds of youth gun carrying (adjusted odds ratio [AOR], 0.91 [95% CI, 0.86-0.96]). Adult gun ownership mediated the association between state gun law score and youth gun carrying (AOR, 0.94 [ 95% CI, 0.86-1.01], with 29% attenuation of the regression coefficient from -0.09 to -0.07 based on bootstrap resampling). More restrictive overall gun control policies are associated with a reduced likelihood of youth gun carrying. These findings are relevant to gun policy debates about the critical importance of strengthening overall gun law environment to prevent youth gun carrying.

  1. Glove powder's carrying capacity for latex protein: analysis using the ASTM ELISA test.

    Science.gov (United States)

    Beezhold, D; Horton, K; Hickey, V; Daddona, J; Kostyal, D

    2003-01-01

    Glove donning powders carry latex proteins and disperse them into the workplace environment. We have used the ASTM D6499 ELISA to quantify the amount of latex antigen bound to and carried by glove powders. We could differentiate between a small amount of protein actually bound to the powders and a larger amount carried by the powder. Enhanced binding of a major allergen, Hev b 5, to the starch powders was demonstrated by Western blot. The D6499 ELISA is able to measure total latex antigen, soluble and powder bound, simultaneously without the need to centrifuge the samples.

  2. Quantifying spatially derived carrying capacity occupation: Framework for characterisation modelling and application to terrestrial acidification

    DEFF Research Database (Denmark)

    Bjørn, Anders; Margni, M.; Bulle, C.

    *year. This metric resembles that of the ecological footprint method and may be compared to the availability of land or water. The framework was applied to the terrestrial acidification impact category. The geochemical steady-state model PROFILE was used to quantify carrying capacities as deposition levels......The popularity of the ecological footprint method and the planetary boundaries concept shows an increasing interest among decision makers in comparing environmental impacts to carrying capacities of natural systems. Recently carrying capacity-based normalisation references were developed for impact...

  3. On building socially responsible printing: an Organizational Communication Based Study Carried out on Higher Education Institution

    Directory of Open Access Journals (Sweden)

    Silvio Luiz Paula

    2014-04-01

    Full Text Available The main goal of this work is to analyze how organizational communication tools are used to manage printing, from both internal and external audiences, in what regards social responsibility in three Higher Education Institutions from Pernambuco (UFPE, FAFIRE, ASCES. In order to build our theoretical framework, we have used concepts from Printing Management, Corporate Social Responsibility, Stakeholder Theory, Organi-zational Communication, Organizational Culture and Organizational Structure. With respect to culture, a system of representations and shared values emerges, according to Fischer’s Model (1996. This system influences and is influenced by the organizational structure. We present an overview of Higher Education Institutions and their role on building society, according to the argument presented by Calderón (2010. In this work we discuss the creation of socially responsible printing, through communication with the interested audien-ces, as suggested by the model proposed by Mitchell, Agle and Wood (1997. The methodology chosen in this research work is a multiple case study. To this end, we have chosen three institutions, two located in Recife and one in Caruaru, cities in the state of Pernambuco. We have carried out a qualitative investigation. Thus, we have performed a field study with semi-structured interviews, document analysis, direct observations within the institutions in question, as well as indirect observation of photographs and videos. Amongst the results found, the actions performed were shown to be consistent with the management model and culture. The participants of the study have shown us that they are aware of the social role of Higher Education institutions, and have identified the students, professors, workers, students parents, associations, consumers and public service as the main stakeholders involved. Amongst the most commonly used strategies to build a socially responsible strategy, we can highlight

  4. Carrying Capacity Model Applied to Coastal Ecotourism of Baluran National Park, Indonesia

    Science.gov (United States)

    Armono, H. D.; Rosyid, D. M.; Nuzula, N. I.

    2017-07-01

    The resources of Baluran National Park have been used for marine and coastal ecotourism. The increasing number of visitors has led to the increasing of tourists and its related activities. This condition will cause the degradation of resources and the welfare of local communities. This research aims to determine the sustainability of coastal ecotourism management by calculating the effective number of tourists who can be accepted. The study uses the concept of tourism carrying capacity, consists the ecological environment, economic, social and physical carrying capacity. The results of the combined carrying capacity analysis in Baluran National Park ecotourism shows that the number of 3.288 people per day (151.248 tourists per year) is the maximum number of accepted tourists. The current number of tourist arrivals is only 241 people per day (87.990 tourists per year) which is far below the carrying capacity.

  5. Geometry of carrying simplices of 3-species competitive Lotka-Volterra systems

    Science.gov (United States)

    Baigent, Stephen

    2013-04-01

    We investigate the existence, uniqueness and Gaussian curvature of the invariant carrying simplices of 3 species autonomous totally competitive Lotka-Volterra systems. Explicit examples are given where the carrying simplex is convex or concave, but also where the curvature is not single-signed. Our method monitors the curvature of an evolving surface that converges uniformly to the carrying simplex, and generally relies on establishing that the Gaussian image of the evolving surface is confined to an invariant cone. We also discuss the relationship between the curvature of the carrying simplex near an interior fixed point and its Split Lyapunov stability. Finally we comment on extensions to general Lotka-Volterra systems that are not competitive.

  6. 76 FR 16239 - Moratorium on New Exemptions for Passenger Carrying Operations Conducted for Compensation and...

    Science.gov (United States)

    2011-03-23

    ... holder to operate a large, crew-served, piston-powered, multiengine, World War II (WWII) bomber carrying... experience flight in these aircraft. A 2004 policy explicitly limited the scope of LHFE exemptions to WWII...

  7. Spawner-recruit relationships and fish stock carrying capacity in aquatic ecosystems

    DEFF Research Database (Denmark)

    MacKenzie, Brian; Myers, R.A.; Bowen, K.G.

    2003-01-01

    Few marine ecologists have addressed important questions about the relative productivity and carrying capacity of different ecosystems required to support fish populations. Whereas many researchers have investigated interannual variability in recruitment within a stock, we asked whether...

  8. Test-retest reliability of lifting and carrying in a 2-day functional capacity evaluation.

    Science.gov (United States)

    Reneman, M F; Dijkstra, P U; Westmaas, M; Göeken, L N H

    2002-12-01

    The objectives of this study were to establish test-retest reliability of lifting and carrying of a functional capacity evaluation (FCE) on two consecutive days and to verify the need for a 2-day protocol. A cohort of 50 patients (39 men, 11 women) with nonspecific low back pain were evaluated using a 2-day FCE protocol. Intraclass correlation coefficients (ICC) were calculated for weight lifted and carried. Predictive relationships between test and retest were explored by means of a regression analysis. The results of ICC were lifting low 0.87, lifting overhead 0.87, and carrying 0.77. Performances on day 2 were on an average 6-9% higher. Other than the amount of weight handled on day 1, no variable was found to predict performance on day 2. It was concluded that test-retest reliability of lifting and carrying was good, and the need for a 2-day protocol could not be confirmed.

  9. The importance of carrying a backpack in the rehabilitation of osteoporotic patients (biomechanical analysis).

    Science.gov (United States)

    Wendlova, J

    2011-01-01

    Based on a simple biomechanical analysis available to physicians, the article recommends carrying a backpack regularly as a part of the complex rehabilitation of osteoporotic patients. Carrying a backpack in front or on the back is recommended to patients with uncomplicated osteoporosis, while carrying a backpack on the back only is recommended to patients with osteporotic vertebral fractures. The importance of carrying a backpack is based upon removing the muscular dysbalance of the trunk muscles and upon increasing the bone strength by compressive force acting upon the vertebrae and proximal femur and activating osteoblasts to enhance the process of osteoformation. The backpack load is differentiated--patients with vertebral fractures put a weight up to 1 kg into their backpacks, patients without vertebral fractures increase the load up to 2 kg (Fig. 2, Ref. 12).

  10. Magnetic guide of cold atoms using a U-shaped current-carrying conductor

    Institute of Scientific and Technical Information of China (English)

    刘南春; 印建平

    2003-01-01

    We propose a new scheme to magnetically guide cold neutral atoms using a U-shaped current carrying conductor.The spatial magnetic field distribution from the U-shaped current-carrying conductor and the relationship between the magnetic field and parameters of the U-shaped conductor are analysed.Our study shows that U-shaped current-carrying conductor can be used to realize single-or double-channel magnetic guiding of cold atoms in weak-field-seeking states and to construct wrious atom-optical elements.By using Monte Carlo simulations,the dynamic process of the guided atomic-beam splitting in an atomic-beam splitter composed by the U-shaped current-carrying conductor is studied,and some results are presented.

  11. CARRIE web service: automated transcriptional regulatory network inference and interactive analysis.

    Science.gov (United States)

    Haverty, Peter M; Frith, Martin C; Weng, Zhiping

    2004-07-01

    We present an intuitive and interactive web service for CARRIE (Computational Ascertainment of Regulatory Relationships Inferred from Expression). CARRIE is a computational method that analyzes microarray and promoter sequence data to infer a transcriptional regulatory network from the response to a specific stimulus. This service displays an interactive graph of the inferred network and provides easy access to the evidence for the involvement of each gene in the network. We provide functionality to include network data in KEGG XML (KGML) format in this graph. Our service also provides Gene Ontology annotation to aid the user in forming hypotheses about the role of each gene in the cellular response. The CARRIE web service is freely available at http://zlab.bu.edu/CARRIE-web.

  12. Recreation carrying capacity estimations to support beach management at Praia de Faro, Portugal

    OpenAIRE

    Zacarias, D. A.; Williams, Allan T.; Newton, Alice

    2011-01-01

    The purpose of this research paper is to outline the theory and practice of tourism carrying capacity assessment and its relevance as a management tool for coastal management. Based on the Tourism Carrying Capacity Assessment for Protected Areas Framework and the Image Capture Technique associated with the PAOT (people at one time) approach, this paper explores Praia de Faro as the study area and attempts to assess the optimum number of people that should be allowed without jeopar...

  13. Heat Transfer Enhancement by Fluidized Solid Particles in Gas Carrying Evaporation

    Institute of Scientific and Technical Information of China (English)

    于志家; 孙成新; 孙相彧; 刘展红

    2001-01-01

    Heat transfer characteristics are studied for gas carrying evaporation with fluidized solid particles in a vertical rectangular conduit. Experimental results show that heat transfer of gas carrying evaporation is enhanced and the superheat of liquid in contact with heating surface lowers remarkably by introducing solid particles. Nucleate boiling on the heating surface is suppressed to a considerable degree. The mechanism of heat transfer enhancement by fluidized solid particles is analyzed with the consideration of collisions of solid particles with the boiling vapor bubbles.

  14. A 5-year audit of outcome of apicectomies carried out in a district general hospital.

    OpenAIRE

    Lyons, A. J.; Hughes, C E; Dixon, E. J.

    1995-01-01

    Success rates of up to 90% have been claimed for apicectomy. However, the conditions that this procedure is carried out under at district general hospitals may be at variance with such studies. A 5-year audit of outcome was therefore carried out within a district general hospital. It was found that 89% of apicected teeth still remained at 5 years. Outcome was not influenced by any of the factors examined, and could not be predicted radiographically. Most failures occurred after the average po...

  15. Analysis of Interpersonal Relationship in the Consumer Society Context in Sister Carrie

    Institute of Scientific and Technical Information of China (English)

    张恩秀

    2009-01-01

    Carrie's characterization is a familiar topic in the criticism in Sister Carrie. However, how it could be re-viewed in the context of the consumer society is relalively a new issue. This paper attempts to analyze the interpersonal relationship in the context of a consumer society. It explores the consumer society's influences on the lovers and family. In addition, it points out Dreiser's ambivalent attitude towards consumer ideology.

  16. Theoretical Research of the Urban Comprehensive Carrying Capacity in the Epoch of Urbanization

    OpenAIRE

    Li Changliang; Lian Lina

    2012-01-01

    Conventional wisdom suggests that ecological factors are prominent constraints of cities in the urbanization process. By contrast, this article provides a fresh conception of the urban comprehensive carrying capacity in the context of ecosystem, economy and social dimensions. Based on in-depth analysis, the author makes out a list of informative area-based indicators in three differentiated layers and the findings are that the urban comprehensive carrying capacity is an entanglement of three ...

  17. Load-carrying capacity test of a long-span timber truss

    OpenAIRE

    Branco, Jorge M.; Varum, Humberto; Ramisote, Vitor; Costa, Aníbal

    2016-01-01

    The aim of this work was to study the behavior of existing timber trusses in order to improve the knowledge that may support engineers in the definition of more adequate restoration interventions in old buildings, particularly of long-span timber structures, as industrial or monumental constructions. For this purpose, a cyclic load-carrying test was carried out on a full-scale timber planar truss rescued from an old industrial roof structure. Before the tests, an accurate geometrical characte...

  18. Methicillin-resistant Staphylococcus saprophyticus in Sweden carries various types of staphylococcal cassette chromosome mec (SCCmec).

    Science.gov (United States)

    Söderquist, B; Berglund, C

    2009-12-01

    Staphylococcus saprophyticus is a common cause of uncomplicated urinary tract infections and is usually susceptible to the antimicrobial agents used for their treatment. However, S. saprophyticus resistant to beta-lactam antibiotics and carrying mecA has been reported. Eight Swedish isolates of mecA-positive S. saprophyticus with diverse origin carrying at least three different types of staphylococcal cassette chromosome mec (SCCmec) are described here.

  19. Evaluating Beijing's human carrying capacity from the perspective of water resource constraints.

    Science.gov (United States)

    Zhang, Yingxuan; Chen, Min; Zhou, Wenhua; Zhuang, Changwei; Ouyang, Zhiyun

    2010-01-01

    As the demands on limited water resources intensify, concerns are being raised about the human carrying capacity of these resources. However, few researchers have studied the carrying capacity of regional water resources. Beijing, the second-largest city in China, faces a critical water shortage that will limit the city's future development. We developed a method to quantify the carrying capacity of Beijing's water resources by considering water-use structures based on the proportions of water used for agricultural, industrial, and domestic purposes. We defined a reference structure as 45:22:33 (% of total, respectively), an optimized structure as 40:20:40, and an ideal structure as 50:15:35. We also considered four domestic water quotas: 55, 75, 95, and 115 m3/(person x yr). The urban carrying capacity of 10-12 million was closest to Beijing's actual 2003 population for all three water-use structures with urban domestic water use of 75 m3/(person x yr). However, after accounting for our underlying assumptions, the adjusted carrying capacity is closer to 5-6 million. Thus, Beijing's population in 2003 was almost twice the adjusted carrying capacity. Based on this result, we discussed the ecological and environmental problems created by Beijing's excessive population and propose measures to mitigate these problems.

  20. Sensitivity of the speed evaluation tests of carrying the ball in youth soccer players

    Directory of Open Access Journals (Sweden)

    Rakojević Bojan

    2016-01-01

    Full Text Available This research is aimed at examining sensitivity of the speed evaluation tests while carrying the ball. The research included 76 male examinees, aged 17 years (+/- 6 months, who were divided into two qualitatively different subgroups. For determining the speed while carrying the ball, the tests of M type of carrying the ball between cones and slalom ball carrying with a pass were performed. The obtained results proved that the examinees from the group of more successful soccer players (Group 1 scored better on the applied tests when compared to the results of the group consisting of the soccer players from lower ranked clubs and who are not national team members (Group 2. High values of the result homogeneity in the two groups (for the Groups 1 and 2 it was 75% and 68.75% respectively lead to the conclusion that this ability is essential characteristics of young soccer players. The coefficient of discrimination of 0.269 for the results of M type test and 0.197 for the results of the test of carrying the ball with a pass indicate that the results of the two tests provide possibility to qualitatively distinguish youth players. Therefore, it can be concluded that as a technical element, carrying the ball significantly affects the quality of players' performance.

  1. DEVELOPMENT AND TESTING OF PROCEDURES FOR CARRYING OUT EMERGENCY PHYSICAL INVENTORY TAKING AFTER DETECTING ANOMALY EVENTS CONCERNING NM SECURITY.

    Energy Technology Data Exchange (ETDEWEB)

    VALENTE,J.FISHBONE,L.ET AL.

    2003-07-13

    In the State Scientific Center of Russian Federation - Institute of Physics and Power Engineering (SSC RF-IPPE, Obninsk), which is under Minatom jurisdiction, the procedures for carrying out emergency physical inventory taking (EPIT) were developed and tested in cooperation with the Brookhaven National Laboratory (USA). Here the emergency physical inventory taking means the PIT, which is carried out in case of symptoms indicating a possibility of NM loss (theft). Such PIT often requires a verification of attributes and quantitative characteristics for all the NM items located in a specific Material Balance Area (MBA). In order to carry out the exercise, an MBA was selected where many thousands of NM items containing highly enriched uranium are used. Three clients of the computerized material accounting system (CMAS) are installed in this MBA. Labels with unique (within IPPE site) identification numbers in the form of digit combinations and an appropriate bar code have been applied on the NM items, containers and authorized locations. All the data to be checked during the EPIT are stored in the CMAS database. Five variants of anomalies initiating EPIT and requiring different types of activities on EPIT organization are considered. Automatic working places (AWP) were created on the basis of the client computers in order to carry out a large number of measurements within a reasonable time. In addition to a CMAS client computer, the main components of an AWP include a bar-code reader, an electronic scale and an enrichment meter with NaI--detector--the lMCA Inspector (manufactured by the Canberra Company). All these devices work together with a client computer in the on-line mode. Special computer code (Emergency Inventory Software-EIS) was developed. All the algorithms of interaction between the operator and the system, as well as algorithms of data exchange during the measurements and data comparison, are implemented in this software. Registration of detected

  2. Effects of carry-over of fluoroquinolones on the susceptibility of commensal Escherichia coli in the intestinal microbiota of poultry.

    Science.gov (United States)

    Scherz, Gesine; Stahl, Jessica; Glünder, Gerhard; Kietzmann, Manfred

    2014-01-01

    Due to the frequent use of antibacterials in veterinary medicine as well as in human medicine the occurrence of antibacterial resistance rises worldwide. But independent of the usage of antimicrobials the microbiota from animals as well as from humans already harbour a diversity of resistance genes. As a consequence of manufacturing animal production the treatment of livestock in case of illness is carried out via feed or drinking water. This automatically implies several risks. It has been demonstrated that an antibiotic treatment of livestock via feed or drinking water cause an accumulation of antibiotics and their metabolites in the direct environment of animals. This can lead to a carry-over or rather a resumption of the antimicrobials and their metabolites. Thus, the aim of this study was to determine the influence of carry-over of enrofloxacin as a representative of the fluoroquinolones on the development of bacterial resistance of commensal E. coli in the intestinal microbiota of poultry. Therefore four different treatment groups were provided and the minimal inhibitory concentrations (MICs) of commensal E. coli were measured: One group acted as untreated control, another one was therapeutically treated with the recommended dosage. The third and fourth group were exposed to different "carry-over dosages" for three weeks, 3% of the recommended dosage were applied to the third and 10% to the fourth group. To determine the influence of a therapeutic treatment on a prestressed microbiota, both groups were treated with the recommended dosage for five days. The present study demonstrates that every kind of exposure of the commensal microbiota of poultry with enrofloxacin leads to an amplification and selection of resistant E. coli, which persist in the commensal microbiota. A long-term exposure of gut microbiota, which already harbour non-wild type E. coli, with high levels of carry-over of fluoroquinolones may lead to a development of high-level clinically

  3. Spatial patterns of ecological carrying capacity supply-demand balance in China at county level

    Institute of Scientific and Technical Information of China (English)

    LIU Dong; FENG Zhiming; YANG Yanzhao; YOU Zhen

    2011-01-01

    A balanced ecological carrying capacity and its understanding are important to achieve sustainable development for human kind.Here,the concept of ecological carrying capacity has been used for measuring the dependencies between human and nature.China's ecological balance between supply and demand has become a global concern and is widely debated.In this study the 'Ecological Footprint' method was used to analyze the supply-demand balance of China's ecological carrying capacity.Firstly,the ecological supply and demand balance was calculated and evaluated,and secondly,the ecological carrying capacity index (ECCI) was derived for each county of China in 2007,and finally this paper systematically evaluated the ecological carrying capacity supply-demand balance of China.The results showed that ecological deficit appeared to be the main characteristic of ecological carrying capacity supply-demand balance in 2007 of China at county scale.In general,more than four-fifths of the Chinese population was concentrated in less than one-third of the land area and more than two-thirds of the land.area was inhabited by less than one-fifth of the population.The spatial distribution of the ecological carrying capacity demand-supply was unbalanced ranging from significant overloading to affluence from southeastern to northwestern part of China.It appeared to be more dominant in regions located at coastal areas which are attracted by migrants and had a generally higher population density.Along with the rapid development and urbanization trends in China,ecological deficits in these regions will become more severe.

  4. Why do three-wheelers carrying schoolchildren suffer very low fatal crashes?

    Directory of Open Access Journals (Sweden)

    Gaurav Pandey

    2015-03-01

    Full Text Available This paper investigates the possible causes of low fatalities in three-wheelers (autorickshaw carrying schoolchildren in India. The data was collected in the form of First Information Report (FIR from local police stations from 2007 to 2012 and video-graphic surveys were done on four arterial roads running through Ludhiana, Punjab, India. Surveys were also done on one subarterial road near school zone which was used by three-wheelers carrying schoolchildren. The objective of the study was to investigate the hypothesis that drivers behave differently while following or overtaking three-wheelers carrying children. Many researchers have investigated the effect of passengers on the driver of the same vehicle, but there was no evidence of any study which investigated the effect of child passengers on nearby vehicles. It was found that heavy vehicles maintain more gaps while following or overtaking three-wheelers carrying children as compared to those not carrying children. It was also found that this effect is more prominent at speeds higher than 40 km/h. On the other hand lighter vehicles keep the highest lateral and longitudinal gaps to heavy vehicles and three-wheelers without children respectively.

  5. A protocol for clinical evaluation of the carrying angle of the elbow by anatomic landmarks.

    Science.gov (United States)

    Zampagni, Maria Luisa; Casino, Daniela; Martelli, Sandra; Visani, Andrea; Marcacci, Maurilio

    2008-01-01

    The aim of this work was to present an in vivo protocol to estimate the carrying angle of the elbow in full extension. Forty-four arms were measured by using an electrogoniometer to acquire 3-dimensional coordinates of the landmarks. An algorithm based on the Cardan decomposition method was used to compute the carrying angle and the flexion and pronation angles of the elbow. The mean carrying angle was 12.42 degrees +/- 4.06 degrees , in agreement with the literature and with values obtained by a standard goniometer (r = 0.46; P = .000). Our protocol provided excellent repeatability (interclass correlation coefficient [ICC] = 0.85), greater than a goniometer (ICC = 0.76), and a standard error of measurement of only 1.62 degrees . Flexion was a significant factor (P = .01) in carrying angle estimation. This study suggests that the carrying angle cannot be estimated independently by the flexion angle, even when measured in apparently full extension, and it could be useful in elbow disorders, such as fractures or epicondylar disease management and evaluation of elbow reconstruction.

  6. Evaluation of Ecological Carrying Capacity of Henan Province under the Sustainable Development

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    Based on the overview of social economy of Henan Province,I probe into the concept and evaluation of ecological carrying capacity.By using the ecological footprint analysis and the data of various kinds of land supply of Henan Province from 2000 to 2008,the ecological carrying capacity of Henan Province is analyzed.It is unveiled that inharmonious population,natural resources and economic resources affect the efficiency of the sustainable development of ecological carrying capacity of Henan Province;the underdeveloped economy of Henan Province impacts the sustainable development of ecological carrying capacity of Henan Province and the overburdened population lead to the insufficiency of ecological carrying capacity.Around protecting the threshold of ecological system,the countermeasures are put forward,which cover forming the idea of ecological economy and circular economy and promoting the transformation of economy growth mode;taking the development road of using resources intensively and performing the strategy of sustainable utilization of resources;strictly control population growth and strengthening people’s crisis awareness of resources and environment.

  7. Profile of women who carried out smoking cessation treatment: a systematic review

    Directory of Open Access Journals (Sweden)

    Caroline Figueira Pereira

    2015-01-01

    Full Text Available OBJECTIVE Analyze the profile of women, in health services, who carry out treatment for smoking cessation. METHODS Systematic review that used the following sources of information: Cummulative Index to Nursing and Allied Health Literature (CINAHL, PubMed, Biblioteca Virtual em Saúde (BVS, Scopus and Web of Science. We included quantitative studies that addressed the characterization of women, in health services, who carried out treatment for smoking cessation, resulting in 12 articles for analysis. The assessment of the methodological quality of the studies was performed using the instrument MAStARI from Joanna Briggs Institute. RESULTS The predominant profile of women who carried out treatment for smoking cessation in health services was composed of white, married, employed, and highly level educated women. Women who carried out the treatment for smoking cessation in specialized services had a more advanced age, were white, were married and had a diagnosis of depression. The quality level of most studies was moderate. CONCLUSIONS The profile of women who carry out treatment for smoking cessation, either in general or specialized health services, is composed of white, married, and highly level educated women. Publications about smoking women are scarce and the lack of Brazilian studies characterizing the profile of women who start treatment for smoking cessation shows the need for studies that explore this subject.

  8. Carrying capacity of U.S. agricultural land: Ten diet scenarios

    Directory of Open Access Journals (Sweden)

    Christian J. Peters

    2016-07-01

    Full Text Available Abstract Strategies for environmental sustainability and global food security must account for dietary change. Using a biophysical simulation model we calculated human carrying capacity under ten diet scenarios. The scenarios included two reference diets based on actual consumption and eight “Healthy Diet” scenarios that complied with nutritional recommendations but varied in the level of meat content. We considered the U.S. agricultural land base and accounted for losses, processing conversions, livestock feed needs, suitability of land for crops or grazing, and land productivity. Annual per capita land requirements ranged from 0.13 to 1.08 ha person-1 year-1 across the ten diet scenarios. Carrying capacity varied from 402 to 807 million persons; 1.3 to 2.6 times the 2010 U.S. population. Carrying capacity was generally higher for scenarios with less meat and highest for the lacto-vegetarian diet. However, the carrying capacity of the vegan diet was lower than two of the healthy omnivore diet scenarios. Sensitivity analysis showed that carrying capacity estimates were highly influenced by starting assumptions about the proportion of cropland available for cultivated cropping. Population level dietary change can contribute substantially to meeting future food needs, though ongoing agricultural research and sustainable management practices are still needed to assure sufficient production levels.

  9. Carrying weapons and intent to harm among Victorian secondary school students in 1999 and 2009.

    Science.gov (United States)

    Hemphill, Sheryl A; Tollit, Michelle A; Romaniuk, Helena; Williams, Joanne; Toumbourou, John W; Bond, Lyndal; Patton, George C

    2013-12-16

    To examine comparable survey data across 10 years to assess whether rates of self-reported weapon carrying and intent to harm others have increased as suggested in reported trends in violent offences. Population-based surveys administered to Victorian secondary school students in 1999 (8984 students) and 2009 (10 273 students) attending government, Catholic and independent schools. Student self-reports of carrying a weapon and attacking someone with the intent to harm in the past 12 months. In both surveys, about 15.0% of students reported carrying a weapon and about 7.0% reported attacking someone with intent to harm in the past 12 months, with higher rates among boys than girls. There was no change over time in the rates of students carrying weapons or attacking someone with the intent to harm, after controlling for demographic variables. In contrast to media portrayals and reported trends in violent offences, rates of students carrying weapons and attacking others with intent to harm have not changed between 1999 and 2009. These findings underline the importance of having national population-based data to regularly monitor the rates of these and related behaviours among young Australians.

  10. Variation in local carrying capacity and the individual fate of bacterial colonizers in the phyllosphere.

    Science.gov (United States)

    Remus-Emsermann, Mitja N P; Tecon, Robin; Kowalchuk, George A; Leveau, Johan H J

    2012-04-01

    Using a phyllosphere model system, we demonstrated that the term 'carrying capacity', as it is commonly used in microbial ecology, needs to be understood as the sum of many 'local carrying capacities' in order to better explain and predict the course and outcome of bacterial colonization of an environment. Using a green fluorescent protein-based bioreporter system for the quantification of reproductive success (RS) in individual Erwinia herbicola cells, we were able to reconstruct the contribution of individual immigrants to bacterial population sizes on leaves. Our analysis revealed that plant foliage represents to bacteria an environment where individual fate is determined by the local carrying capacity of the site where an immigrant cell lands. With increasing inoculation densities, the RS of most immigrants declined, suggesting that local carrying capacity under the tested conditions was linked to local nutrient availability. Fitting the observed experimental data to an adapted model of phyllosphere colonization indicated that there might exist three types of sites on leaves, which differ in their frequency of occurrence and local carrying capacity. Specifically, our data were consistent with a leaf environment that is characterized by few sites where individual immigrants can produce high numbers of offspring, whereas the remainder of the leaf offered an equal number of sites with low and medium RS. Our findings contribute to a bottom-up understanding of bacterial colonization of leaf surfaces, which includes a quantifiable role of chance in the experience at the individual level and in the outcome at the population level.

  11. La ascendencia paterna de Daniel Carrión García

    Directory of Open Access Journals (Sweden)

    Ricardo Álvarez

    2008-09-01

    Full Text Available Daniel Carrión García, mártir de la medicina peruana y héroe nacional, tenía antiguas raíces peruanas por línea materna, pero su ascendencia paterna era netamente ecuatoriana. Los Carrión fueron una de las familias más prominentes de la ciudad de Loja, a tal punto que, en 1830, al elegirse el primer Presidente de la República del Ecuador, uno de los dos candidatos fue don Manuel Carrión. La participación política de la familia continuó en los años siguientes y uno de sus miembros, el doctor José Baltazar Carrión y Torres, padre de Daniel, unió su destino al del General Juan José Flores, quien al caer en desgracia, luego de un frustrado intento revolucionario, lo arrastró consigo y debió exiliarse en el Perú. Nuestro objetivo es contribuir al conocimiento de la ascendencia paterna de Daniel Carrión García.

  12. Profile of women who carried out smoking cessation treatment: a systematic review

    Science.gov (United States)

    Pereira, Caroline Figueira; de Vargas, Divane

    2015-01-01

    OBJECTIVE Analyze the profile of women, in health services, who carry out treatment for smoking cessation. METHODS Systematic review that used the following sources of information: Cummulative Index to Nursing and Allied Health Literature (CINAHL), PubMed, Biblioteca Virtual em Saúde (BVS), Scopus and Web of Science. We included quantitative studies that addressed the characterization of women, in health services, who carried out treatment for smoking cessation, resulting in 12 articles for analysis. The assessment of the methodological quality of the studies was performed using the instrument MAStARI from Joanna Briggs Institute. RESULTS The predominant profile of women who carried out treatment for smoking cessation in health services was composed of white, married, employed, and highly level educated women. Women who carried out the treatment for smoking cessation in specialized services had a more advanced age, were white, were married and had a diagnosis of depression. The quality level of most studies was moderate. CONCLUSIONS The profile of women who carry out treatment for smoking cessation, either in general or specialized health services, is composed of white, married, and highly level educated women. Publications about smoking women are scarce and the lack of Brazilian studies characterizing the profile of women who start treatment for smoking cessation shows the need for studies that explore this subject. PMID:26247386

  13. On Sister Carrie from Feminist Perspective and its Influence on Chinese Modern Women

    Institute of Scientific and Technical Information of China (English)

    毛武毅; 叶青

    2013-01-01

    Sister Carrie is a famous naturalistic novelist-Theodore Dreiser’s first novel in the first 20th century. It tells a story of a young rural woman Carrie how to become the red Broadway actress from the bottom of society, and the story vividly depicts the survival state and psychological and ideological process of Carrie. When it was published, it attracted attentions of critics from domestic and abroad at large, and they researched it from different perspectives. But most of their researches discussed from the materialism angle to concern with the expression of Determinism and Darwinism. So far, few people made the research from the topic of Carrie’s pursuit of self-achievement and perspective of feminist. Actually, not only did Carrie restrict on the material pursuit, but also boldly in pursuit of the self-achievement of new women. This paper aims at Carrie how to pursue the self-achievement of new women, and the influence of feminist to Chinese modern women.

  14. Profile of women who carried out smoking cessation treatment: a systematic review.

    Science.gov (United States)

    Pereira, Caroline Figueira; de Vargas, Divane

    2015-01-01

    OBJECTIVE Analyze the profile of women, in health services, who carry out treatment for smoking cessation. METHODS Systematic review that used the following sources of information: Cummulative Index to Nursing and Allied Health Literature (CINAHL), PubMed, Biblioteca Virtual em Saúde (BVS), Scopus and Web of Science. We included quantitative studies that addressed the characterization of women, in health services, who carried out treatment for smoking cessation, resulting in 12 articles for analysis. The assessment of the methodological quality of the studies was performed using the instrument MAStARI from Joanna Briggs Institute. RESULTS The predominant profile of women who carried out treatment for smoking cessation in health services was composed of white, married, employed, and highly level educated women. Women who carried out the treatment for smoking cessation in specialized services had a more advanced age, were white, were married and had a diagnosis of depression. The quality level of most studies was moderate. CONCLUSIONS The profile of women who carry out treatment for smoking cessation, either in general or specialized health services, is composed of white, married, and highly level educated women. Publications about smoking women are scarce and the lack of Brazilian studies characterizing the profile of women who start treatment for smoking cessation shows the need for studies that explore this subject.

  15. Comprehensive Measurement for Carrying Capacity of Resources and Environment of City Clusters in Central China

    Institute of Scientific and Technical Information of China (English)

    FANG Chuanglin; LIU Xiaoli

    2010-01-01

    Studying the carrying capacity of resources and environment of city clusters in the central China has impor-tant practical guidance significance for promoting the healthy,sustainable and stable development of this region.Ac-cording to their influencing factors and reciprocity mechanism,using system dynamics approaches,this paper built a SD model for measuring the carrying capacity of resources and environment of the city clusters in the central China,and through setting different development models,the comprehensive measurement analysis on the carrying capacity was carried out.The results show that the model of promoting socio-economic development under the protection of resources and environment is the optimal model for promoting the harmony development of resources,environment,society and economy in the city clusters.According to this model,the optimum population scale of the city clusters in2020 is 42.80×106 persons,and the moderate economic development scale is 22.055× 1012 yuan(RMB).In 1996-2020,the carrying capacity of resources and environment in the city clusters took on obvious phase-change characteristics.During the studied period,it is basically at the initial development stage,and will come through the development process from slow development to speedup development.

  16. The evolution of carrying capacity in constrained and expanding tumour cell populations.

    Science.gov (United States)

    Gerlee, Philip; Anderson, Alexander R A

    2015-08-12

    Cancer cells are known to modify their micro-environment such that it can sustain a larger population, or, in ecological terms, they construct a niche which increases the carrying capacity of the population. It has however been argued that niche construction, which benefits all cells in the tumour, would be selected against since cheaters could reap the benefits without paying the cost. We have investigated the impact of niche specificity on tumour evolution using an individual based model of breast tumour growth, in which the carrying capacity of each cell consists of two components: an intrinsic, subclone-specific part and a contribution from all neighbouring cells. Analysis of the model shows that the ability of a mutant to invade a resident population depends strongly on the specificity. When specificity is low selection is mostly on growth rate, while high specificity shifts selection towards increased carrying capacity. Further, we show that the long-term evolution of the system can be predicted using adaptive dynamics. By comparing the results from a spatially structured versus well-mixed population we show that spatial structure restores selection for carrying capacity even at zero specificity, which poses a solution to the niche construction dilemma. Lastly, we show that an expanding population exhibits spatially variable selection pressure, where cells at the leading edge exhibit higher growth rate and lower carrying capacity than those at the centre of the tumour.

  17. Categorical and continuous - disentangling the neural correlates of the carry effect in multi-digit addition

    Directory of Open Access Journals (Sweden)

    Dressel Katharina

    2010-11-01

    Full Text Available Abstract Background Recently it was suggested that the carry effect observed in addition involves both categorical and continuous processing characteristics. Methods In the present study, we aimed at identifying the specific neural correlates associated with processing either categorical or continuous aspects of the carry effect in an fMRI study on multi-digit addition. Results In line with our expectations, we observed two distinct parts of the fronto-parietal network subserving numerical cognition to be associated with either one of these two characteristics. On the one hand, the categorical aspect of the carry effect was associated with left-hemispheric language areas and the basal ganglia probably reflecting increased demands on procedural and problem solving processes. Complementarily, the continuous aspect of the carry effect was associated with increased intraparietal activation indicating increasing demands on magnitude processing as well as place-value integration with increasing unit sum. Conclusions In summary, the findings suggest representations and processes underlying the carry effect in multi-digit addition to be more complex and interactive than assumed previously.

  18. Integrated Assessment and Obstacle Factors of Environmental Carrying Capacity of National Strategic Economic Zones Based on Entropy and Catastrophe Progression Methods:A Case Study in Changchun-Jilin-Tumenjiang Development and Opening-up Pilot Area%基于熵值-突变级数法的国家战略经济区环境承载力综合评价及障碍因子——以长吉图开发开放先导区为例

    Institute of Scientific and Technical Information of China (English)

    赵宏波; 马延吉; 苗长虹

    2015-01-01

    The environmental carrying capacity is a parameter to measure the capacity degree between human being social activities and the environment. To study the theories and quantification, methods of environmental carrying capacity is of significance in reality for directing human beings economic behaviors and harmonizing the relationships between social development and environment. With the rapid development of social economy and population growth sharply in National Strategic Economic Zones, the resource consumption and pollutant emission are increasing accordingly, which made resources and environment system under tremendous pres-sure, this situation would impact the level of environmental carrying capacity of National Strategic Economic Zones. According to the catastrophic characteristics of environmental carrying capacity of National Strategic Economic Zones, we selected Changchun-Jilin-Tumenjiang development and opening-up Pilot Area as the re-search object. Based on the entropy and catastrophe progression methods, we built an index system to evaluate the environmental carrying capacity, in which Nature-Economy-Society (N-E-S) indexes are included. Using obstacle degree models, we analyzed the temporal pattern of environmental carrying capacity and the obstacle factors from 2000 to 2011.Results are shown as follows:1) Temporally, the level of environmental carrying ca-pacity rose from weak to moderate level from 2000 to 2011. 2) The proportion of environmental protection in-vestment in GDP, industrial waste water emissions, cultivated land fertilizer usage, the per Capita GDP, the en-ergy consumptions per GDP and economic density are the main obstacle factors affecting the environmental carrying capacity. The approach established in the article has a lot advantages when dealing with municipal projects under complex evaluation problems and it does not use any weight, only need to arrange indicators in an order of important degree according to the inherent logic

  19. Design Considerations of a Lower Limb Exoskeleton System to Assist walking and Load-Carrying of Infantry Soldiers

    Directory of Open Access Journals (Sweden)

    Seungnam Yu

    2014-01-01

    Full Text Available This paper describes the development of a wearable exoskeleton system for the lower extremities of infantry soldiers and proposes appropriate design criteria based on existing case studies. Because infantry soldiers carry a variety of equipment, the interference with existing equipment and additional burden of the exoskeleton support system should be minimized. Recent studies have shown that a user only needs to be supported in the gravitational direction when walking on flat terrain; however, active joints are necessary to support walking over rough and sloped terrain such as mountains. Thus, an underactuated exoskeleton system was considered: passive joints are applied to the hip and ankle joints, and active joints are applied to the knee joints to exploit the dynamic coupling effect of the link structure and muscular activation patterns when the user is going up and down stairs. A prototype of the exoskeleton system was developed and validated through a simple stair-climbing experiment.

  20. The quantum-mechanical basis of an extended Landau-Lifshitz-Gilbert equation for a current-carrying ferromagnetic wire.

    Science.gov (United States)

    Edwards, D M; Wessely, O

    2009-04-08

    An extended Landau-Lifshitz-Gilbert (LLG) equation is introduced to describe the dynamics of inhomogeneous magnetization in a current-carrying wire. The coefficients of all the terms in this equation are calculated quantum-mechanically for a simple model which includes impurity scattering. This is done by comparing the energies and lifetimes of a spin wave calculated from the LLG equation and from the explicit model. Two terms are of particular importance since they describe non-adiabatic spin-transfer torque and damping processes which do not rely on spin-orbit coupling. It is shown that these terms may have a significant influence on the velocity of a current-driven domain wall and they become dominant in the case of a narrow wall.

  1. Valproate Treatment in an ALS Patient Carrying a c.194G>A Spastin Mutation and SMN2 Homozygous Deletion

    Directory of Open Access Journals (Sweden)

    Lucio Tremolizzo

    2014-01-01

    Full Text Available Here we report the case of an ALS patient found to carry both a novel heterozygous change (c.194G>A within the spastin gene and a homozygous deletion of the SMN2 gene. The patient was started on valproic acid (VPA, 600 mg/die per os considering the capacity of this drug of increasing survival motor neuron through an epigenetic mechanism. Patient clinical course and molecular effects of VPA on skin fibroblasts obtained from the proband are described. This c.194G>A spastin mutation might expand the previously known borders of type 4 spastic paraplegia (SPG4 and we suggest the intriguing possibility that the absence of SMN2 might have acted as a contributory risk factor for starting lower motor neuron damage. Exploring the relationship genocopy-phenocopy in selected ALS patients might represent an interesting strategy for understanding its clinical variability.

  2. Kettlebell swing, snatch, and bottoms-up carry: back and hip muscle activation, motion, and low back loads.

    Science.gov (United States)

    McGill, Stuart M; Marshall, Leigh W

    2012-01-01

    The intent of this study was to quantify spine loading during different kettlebell swings and carries. No previously published studies of tissue loads during kettlebell exercises could be found. Given the popularity of kettlebells, this study was designed to provide an insight into the resulting joint loads. Seven male subjects participated in this investigation. In addition, a single case study of the kettlebell swing was performed on an accomplished kettlebell master. Electromyography, ground reaction forces (GRFs), and 3D kinematic data were recorded during exercises using a 16-kg kettlebell. These variables were input into an anatomically detailed biomechanical model that used normalized muscle activation; GRF; and spine, hip, and knee motion to calculate spine compression and shear loads. It was found that kettlebell swings create a hip-hinge squat pattern characterized by rapid muscle activation-relaxation cycles of substantial magnitudes (∼50% of a maximal voluntary contraction [MVC] for the low back extensors and 80% MVC for the gluteal muscles with a 16-kg kettlebell) resulting in about 3,200 N of low back compression. Abdominal muscular pulses together with the muscle bracing associated with carries create kettlebell-specific training opportunities. Some unique loading patterns discovered during the kettlebell swing included the posterior shear of the L4 vertebra on L5, which is opposite in polarity to a traditional lift. Thus, quantitative analysis provides an insight into why many individuals credit kettlebell swings with restoring and enhancing back health and function, although a few find that they irritate tissues.

  3. Bronchopneumonia in wild boar (Sus scrofa) caused by Rhodococcus equi carrying the VapB type 8 plasmid.

    Science.gov (United States)

    de Vargas, Agueda Castagna; Monego, Fernanda; Gressler, Letícia Trevisan; de Avila Botton, Sônia; Lazzari, Andrea Maria; da Costa, Mateus Matiuzzi; Ecco, Roselene; Ribeiro, Márcio Garcia; Lara, Gustavo Henrique Batista; Takai, Shinji

    2013-03-25

    Rhodococcus equi is associated with pyogranulomatous infections, especially in foals, and this bacterium has also emerged as a pathogen for humans, particularly immunocompromised patients. R. equi infections in pigs, wild boar (Sus scrofa) and humans are mainly due to strains carrying the intermediate virulence (VapB) plasmid. In Brazil, R. equi carrying the VapB type 8 plasmid is the most common type recovered from humans co-infected with the human immunodeficiency virus (HIV). R. equi infection in pigs and wild boar is restricted predominantly to the lymphatic system, without any reports of pulmonary manifestations. This report describes the microbiological and histopathological findings, and molecular characterization of R. equi in two bronchopneumonia cases in wild boar using PCR and plasmid profile analysis by digestion with restriction endonucleases. The histological findings were suggestive of pyogranulomatous infection, and the plasmid profile of both R. equi isolates enabled the characterization of the strains as VapB type 8. This is the first report of bronchopneumonia in wild boar due to R. equi. The detection of the VapB type 8 plasmid in R. equi isolates emphasize that wild boar may be a potential source of pathogenic R. equi strains for humans.

  4. Carrying capacities for nature parks as engines for sustainable regional development

    DEFF Research Database (Denmark)

    Brandt, Jesper; Holmes, Esbern

    of national and nature parks. Nature parks should rather develop towards a status as 'Biosphere Reserves' representing models for regional development, land use and landscape design in general. A relevant zoning of the regional environment of the Parks will be included as an instrument for such a strategy.......Growth in the number of visitors is an upcoming problem in nature parks. Nature parks are at the same time facing increasing demand, falling public appropriations and receding focus on their conservation functions. To ensure a balancing of nature protection and economic utilization the concept...... of carrying capacity has received increasing attention among park-authorities all over the world. A comparative analysis of conditions and initiatives related to visitor/nature carrying capacities in 8 nature parks in the Baltic region has been carried out. All the parks are candidates for recognition...

  5. Introducing carrying capacity-based normalisation in LCA: framework and development of references at midpoint level

    DEFF Research Database (Denmark)

    Bjørn, Anders; Hauschild, Michael Zwicky

    2015-01-01

    capacity of a reference region divided by its population and thus describes the annual personal share of the carrying capacity.The developed references can be applied to indicator results obtained using commonly applied characterisation models in LCIA. The European NR are generally lower than the global NR...... ozone formation and soil quality were found to exceed carrying capacities several times.The developed carrying capacity-based normalisation references offer relevant supplementary reference information to the currently applied references based on society’s background interventions by supporting...... an evaluation of the environmental sustainability of product systems on an absolute scale.Challenges remain with respect to spatial variations to increase the relevance of the normalisation references for impact categories that function at the local or regional scale. The sensitivity of NR to different choices...

  6. Siblings and Adolescent Weapon Carrying: Contributions of Genetics, Shared Environment, and Nonshared Environment.

    Science.gov (United States)

    Wallace, Lacey N

    2017-07-01

    Many past studies have observed evidence of sibling similarity and influence for delinquency and substance use. However, studies of sibling similarity for adolescent weapon carrying, particularly for weapons beyond firearms, are largely absent from the literature. The present study assesses sibling similarity in weapon carrying as well as the relative contributions of genetics, shared environment, and nonshared environment. Data are obtained from the first two waves of the National Longitudinal Study of Adolescent to Adult Health and analyzed using biometrical genetic models for twins and actor-partner interdependence models for nontwins. Results indicate little, if any, contribution stemming from genetics. There is also no evidence of a significant shared environment effect. Instead, all or nearly all of the variation and similarity in weapon carrying among siblings are related to the nonshared environment, particularly gang affiliation. Implications and possible extensions of these findings are discussed.

  7. First Identification of a Patient Colonized With Klebsiella pneumoniae Carrying blaNDM-1 in Taiwan

    Directory of Open Access Journals (Sweden)

    Hua-Shin Wu

    2010-11-01

    Full Text Available New Delhi metallo-β-lactamase 1 (NDM-1 is a novel type of metallo-β-lactamase (MBL. Enterobacteriaceae carrying this NDM-1 encoding gene, blaNDM-1, have been identified worldwide. Bacteria carrying blaNDM-1 are not only resistant to carbapenem, but also highly resistant to many classes of antibiotics, which indicate the importance of prompt identification of these bacteria and implementation of strict infection control measures to prevent their transmission. Here, we report the first identification and management of a patient colonized with Klebsiella pneumoniae carrying blaNDM-1 in Taiwan, who returned from New Delhi where he had been hospitalized for a gun-shot injury.

  8. Biophysical and RNA Interference Inhibitory Properties of Oligonucleotides Carrying Tetrathiafulvalene Groups at Terminal Positions

    Directory of Open Access Journals (Sweden)

    Sónia Pérez-Rentero

    2013-01-01

    Full Text Available Oligonucleotide conjugates carrying a single functionalized tetrathiafulvalene (TTF unit linked through a threoninol molecule to the 3′ or 5′ ends were synthesized together with their complementary oligonucleotides carrying a TTF, pyrene, or pentafluorophenyl group. TTF-oligonucleotide conjugates formed duplexes with higher thermal stability than the corresponding unmodified oligonucleotides and pyrene- and pentafluorophenyl-modified oligonucleotides. TTF-modified oligonucleotides are able to bind to citrate-stabilized gold nanoparticles (AuNPs and produce stable gold AuNPs functionalized with oligonucleotides. Finally, TTF-oligoribonucleotides have been synthesized to produce siRNA duplexes carrying TTF units. The presence of the TTF molecule is compatible with the RNA interference mechanism for gene inhibition.

  9. Estimating the carrying capacity of green mussel cultivation by using net nutrient removal model.

    Science.gov (United States)

    Srisunont, Chayarat; Babel, Sandhya

    2016-11-15

    This study aims to evaluate the nutrient removal potential and carrying capacity of green mussel cultivation by using the mass balance model. The developed model takes into consideration the green mussel growth rate, density and chlorophyll a concentration. The data employed in this study were based on culture conditions at Sriracha Fisheries Research Station, Thailand. Results show that net nutrient removal by green mussel is 3302, 380, and 124mg/year/indv for carbon, nitrogen, and phosphorus respectively. The carrying capacity of green mussel cultivation was found to be 300indv/m(2) based on chlorophyll a concentration which will not release phosphorus in the water environment beyond the standard (45μg-PO4(-3)-P/L). Higher chlorophyll a concentration results in lowered green mussel carrying capacity. This model can assist farm operators with possible management strategies for a sustainable mussel cultivation and protection of the marine environment.

  10. A 5-year audit of outcome of apicectomies carried out in a district general hospital.

    Science.gov (United States)

    Lyons, A. J.; Hughes, C. E.; Dixon, E. J.

    1995-01-01

    Success rates of up to 90% have been claimed for apicectomy. However, the conditions that this procedure is carried out under at district general hospitals may be at variance with such studies. A 5-year audit of outcome was therefore carried out within a district general hospital. It was found that 89% of apicected teeth still remained at 5 years. Outcome was not influenced by any of the factors examined, and could not be predicted radiographically. Most failures occurred after the average postoperative review period of 10.5 months. Patient satisfaction with the procedure was high at over 90%. Based on these results it was concluded that apicectomy was an effective procedure when carried out by staff of all grades within the district general hospital, and that repeated follow-up appointments with radiographs over the first postoperative year were not useful. PMID:7574319

  11. Conditions for the management of carrying capacity in the parks of Parks&Benefits

    DEFF Research Database (Denmark)

    Brandt, Jesper; Holmes, Esbern

    2011-01-01

    Growth in the number of visitors is an upcoming problem in nature parks. Nature parks are at the same time facing increasing demand, falling public appropriations and receding focus on their conservation functions. To ensure a balancing of nature protection and economic utilization the concept...... of carrying capacity has received increasing attention among park-authorities all over the world. Carrying capacities understood as limits or standards not to be exceeded to protect a supporting landscape system are not scientifically determined sizes. They are a result of political decision processes among...... stakeholders, balancing use and protection preferably based on scientific and/or experiential cognition. The conditions for the management of carrying capacity for the 8 nature parks in the EC Baltic Project Parks&Benefits are analysed in the report. 1. Part focus on the methodology, concentrated...

  12. Threat by association: do distant intergroup threats carry-over into local intolerance?

    Science.gov (United States)

    Bouman, Thijs; van Zomeren, Martijn; Otten, Sabine

    2014-09-01

    Individuals are often confronted with intergroup threats, yet many of these threats emanate from distant groups that most individuals are unlikely to encounter in their local environment. An important yet unanswered question is whether reactions to those threats, such as intolerance towards the threatening group, carry over to other groups that individuals actually do encounter in their local environment (e.g., immigrants). The main goal of our studies was to experimentally identify this carry-over effect of intergroup threat. Specifically, we hypothesized that (by definition relatively abstract) symbolic threats (e.g., threats to the ingroup's worldview) have an especially strong carry-over potential because those threats can be easily attributed to other outgroups. We tested these predictions in one correlational and two experimental studies. The results of all three studies confirmed our hypothesis that particularly distant symbolic threats were predictive of intolerance towards local outgroups.

  13. Missile Captive Carry Monitoring and Helicopter Identification Using a Capacitive Microelectromechanical Systems Accelerometer

    Energy Technology Data Exchange (ETDEWEB)

    Hatchell, Brian K.; Mauss, Fredrick J.; Amaya, Ivan A.; Skorpik, James R.; Silvers, Kurt L.; Marotta, Steve

    2012-03-27

    Military missiles are exposed to many sources of mechanical vibration that can affect system reliability, safety, and mission effectiveness. The U. S. Army Aviation and Missile Research Development and Engineering Center (AMRDEC) has been developing missile health monitoring systems to assess and improve reliability, reduce life cycle costs, and increase system readiness. One of the most significant exposures to vibration occurs when the missile is being carried by a helicopter or other aviation platform, which is a condition known as captive carry. Recording the duration of captive carry exposure during the missile’s service life can enable the implementation of predictive maintenance and resource management programs. Since the vibration imparted by each class of helicopter varies in frequency and amplitude, tracking the vibration exposure from each helicopter separately can help quantify the severity and harmonic content of the exposure. Under the direction of AMRDEC staff, engineers at the Pacific Northwest National Laboratory have developed a Captive Carry Health Monitor (CCHM) for the Hellfire II missile. The CCHM is an embedded usage monitoring device installed on the outer skin of the Hellfire II missile to record the cumulative hours the host missile has been in captive carry mode. To classify the vibration by class of helicopter, the CCHM analyzes the amplitude and frequency content of the vibration with the Goertzel algorithm to detect the presence of distinctive rotor harmonics. Cumulative usage data are accessible in theater from an external display; monthly usage histograms are accessible through an internal download connector. This paper provides an overview of the CCHM electrical and package design, describes field testing and data analysis techniques used to monitor captive carry identify and the class of helicopter, and discusses the potential application of missile health and usage data for real-time reliability analysis and fleet management.

  14. Performance of women with fibromyalgia in walking up stairs while carrying a load

    Directory of Open Access Journals (Sweden)

    Daniel Collado-Mateo

    2016-02-01

    Full Text Available Background. Fibromyalgia is a chronic disease characterized by widespread pain and other associated symptoms. It has a relevant impact on physical fitness and the ability to perform daily living tasks. The objective of the study was to analyze the step-by-step-performance and the trunk tilt of women with fibromyalgia in the 10-step stair climbing test compared with healthy controls. Methods. A cross-sectional study was carried out. Twelve women suffering from fibromyalgia and eight healthy controls were recruited from a local association. Participants were asked to climb 10 stairs without carrying a load and 10 stairs carrying a load of 5 kg in each hand. Mediolateral trunk tilt was assessed using the “Functional Assessment of Biomechanics (FAB” wireless motion capture device, and the time between steps was assessed via weight-bearing insoles. Results. Trunk tilt in the stair-climbing task carrying a load was significantly higher in women with fibromyalgia when compared to the healthy controls (2.31 (0.63 vs. 1.69 (0.51 respectively. The effect of carrying a load was significantly higher for women with fibromyalgia compared with healthy controls at the intermediate and final part of the task. Discussion. Trunk tilt during stair climbing while carrying a load was higher in women with FM, which could increase the risk of falling. Additionally, women with FM experienced a higher pace slowdown as a consequence of the load, which supports the need of including specific strength and resistance training to physical therapies for this population.

  15. Performance of women with fibromyalgia in walking up stairs while carrying a load.

    Science.gov (United States)

    Collado-Mateo, Daniel; Adsuar, José C; Olivares, Pedro R; Dominguez-Muñoz, Francisco J; Maestre-Cascales, Cristina; Gusi, Narcis

    2016-01-01

    Background. Fibromyalgia is a chronic disease characterized by widespread pain and other associated symptoms. It has a relevant impact on physical fitness and the ability to perform daily living tasks. The objective of the study was to analyze the step-by-step-performance and the trunk tilt of women with fibromyalgia in the 10-step stair climbing test compared with healthy controls. Methods. A cross-sectional study was carried out. Twelve women suffering from fibromyalgia and eight healthy controls were recruited from a local association. Participants were asked to climb 10 stairs without carrying a load and 10 stairs carrying a load of 5 kg in each hand. Mediolateral trunk tilt was assessed using the "Functional Assessment of Biomechanics (FAB)" wireless motion capture device, and the time between steps was assessed via weight-bearing insoles. Results. Trunk tilt in the stair-climbing task carrying a load was significantly higher in women with fibromyalgia when compared to the healthy controls (2.31 (0.63) vs. 1.69 (0.51) respectively). The effect of carrying a load was significantly higher for women with fibromyalgia compared with healthy controls at the intermediate and final part of the task. Discussion. Trunk tilt during stair climbing while carrying a load was higher in women with FM, which could increase the risk of falling. Additionally, women with FM experienced a higher pace slowdown as a consequence of the load, which supports the need of including specific strength and resistance training to physical therapies for this population.

  16. Correlates of weapon carrying among high school students in the United States

    Science.gov (United States)

    Muula, Adamson S; Rudatsikira, Emmanuel; Siziya, Seter

    2008-01-01

    Background Deaths and injuries arising from interpersonal violence among adolescents are major public health concerns in the United States. The bearing of weapons among adolescents is a critical factor in many of these deaths and injuries. Methods A secondary analysis of the 2005 United States Youth Risk Behavior Surveillance System Survey data was carried out to examine the variables associated with self-reported history of weapon carrying on school property among high school students. We used logistic regression analysis to assess the associations. Results Of the 13,707 respondents who participated in the survey, 10.2% of males and 2.6% of females reported carrying a weapon on school property. In multivariate logistic regression analysis, males were more likely to report having carried a weapon than females (odds ratio (OR) = 5.58; 95% confidence interval (CI) [4.23, 7.62]). Self-reported race/ethnicity was also associated with weapon carrying. Other variables positively associated with weapon carrying at school were substance use (OR = 1.77; 95% CI [1.16, 2.68]), depression (OR = 1.44; 95% CI [1.10, 1.89]), suicidal ideation (OR = 1.64; 95% CI [1.23, 2.19]), having had property stolen or deliberately damaged at school (OR = 1.55; 95% CI [1.21, 1.98]), having been raped (OR = 1.70; 95% CI [1.22, 2.37]), having been threatened or injured with a weapon on school property (OR = 2.19; 95% CI [1.63, 2.95]), and having engaged in physical fighting (OR = 2.02; 95% CI [1.56, 2.63]). Conclusion This research identifies factors that are associated with weapon bearing among adolescents in the United States. These factors may be important in the design of interventions aimed at improving school safety and adolescent health. PMID:18605995

  17. Performance of women with fibromyalgia in walking up stairs while carrying a load

    Science.gov (United States)

    Adsuar, José C.; Olivares, Pedro R.; Dominguez-Muñoz, Francisco J.; Maestre-Cascales, Cristina; Gusi, Narcis

    2016-01-01

    Background. Fibromyalgia is a chronic disease characterized by widespread pain and other associated symptoms. It has a relevant impact on physical fitness and the ability to perform daily living tasks. The objective of the study was to analyze the step-by-step-performance and the trunk tilt of women with fibromyalgia in the 10-step stair climbing test compared with healthy controls. Methods. A cross-sectional study was carried out. Twelve women suffering from fibromyalgia and eight healthy controls were recruited from a local association. Participants were asked to climb 10 stairs without carrying a load and 10 stairs carrying a load of 5 kg in each hand. Mediolateral trunk tilt was assessed using the “Functional Assessment of Biomechanics (FAB)” wireless motion capture device, and the time between steps was assessed via weight-bearing insoles. Results. Trunk tilt in the stair-climbing task carrying a load was significantly higher in women with fibromyalgia when compared to the healthy controls (2.31 (0.63) vs. 1.69 (0.51) respectively). The effect of carrying a load was significantly higher for women with fibromyalgia compared with healthy controls at the intermediate and final part of the task. Discussion. Trunk tilt during stair climbing while carrying a load was higher in women with FM, which could increase the risk of falling. Additionally, women with FM experienced a higher pace slowdown as a consequence of the load, which supports the need of including specific strength and resistance training to physical therapies for this population. PMID:26855878

  18. Meta-analysis of intrinsic rates of increase and carrying capacity of populations affected by toxic and other stressors.

    Science.gov (United States)

    Hendriks, A Jan; Maas-Diepeveen, Johanna L M; Heugens, Evelyn H W; Van Straalen, Nico M

    2005-09-01

    Most of the thousands of substances and species that are of concern for environmental management will not be investigated empirically at ecologically relevant levels because of financial, practical, and ethical constraints. To allow risk assessment for these less well-known categories, we have developed a mechanistic model with classical equations from toxicology and ecology. The parameters are linked to well-known properties, such as the octanol-water partition ratio K(ow), acute lethal (body) concentrations, and organism size. This allows estimation of intrinsic rates of increase r and carrying capacity K over a wide range of substances and species. The model was calibrated with parameter values (micro +/- 95% confidence interval) obtained in reviews and validated by a meta-analysis with largely independent data from 200 laboratory experiments. For single substances, the 5 to 95% interval of the observations on intrinsic rates of increase overlapped with the range predicted by the model. Model and experiments independently indicated that population growth ceased below 1% of the acute median lethal concentration in about 5% of the cases. Exceptional values and possible explanations were identified. The reduction of the carrying capacity K was nearly proportional to the inhibition of the population growth r. Population-level effects of mixtures as estimated by concentration addition were confirmed by observations in the experiments. The impact of a toxicant and another stressor could generally be described by response multiplication, with the exception of cases with extreme stress. Data sets on population laboratory experiments are biased to metals and crustaceans. This field will benefit from empirical studies on chemicals, conditions, and species, identified as risky by the model. Other implications of the model for environmental management and research are discussed.

  19. A Novel Evaluation algorithm of Urban Comprehensive Carrying Capacity Index System in Northwest China:Lanzhou city as a example

    Science.gov (United States)

    Li, Jing; Lei, Song; Ling, Ma

    2016-06-01

    With the rapid growth of the urban population and quick expansion of urban dimensions, the affecting urban development constraints of urban carrying capacity has increasingly been attracting people's attention. However, the effective synthesization of urban resources carrying capacity, urban environmental carrying capacity, economic carrying capacity, society carrying capacity and traffic carrying capacity hardly acted as an urban comprehensive carrying capacity evaluation system. In this paper, the novel comprehensive index system of urban resources carrying capacity, urban environmental carrying capacity, economic carrying capacity, society carrying capacity and traffic carrying capacity was used for analyzing and evaluating urban comprehensive carrying capacity. Firstly, the standardization of evaluation index was constructed in the urban comprehensive carrying capacity index system. In addition, the past decade data from 2002 to 2011 was analyzed and evaluated in the weighted index system. Finally, the influence mechanism of various carrying capacity factors on urban comprehensive carrying capacity was investigated in Lanzhou. Experimental results can be summarized that the variation tendency of urban comprehensive carrying capacity was the annual increase of levels and the promotion countermeasure was put forward with congenital restricting factors and acquired restricting factors.

  20. Notification on carrying out the special rectification of rare earth production order nationwide

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    To implement "Some Opinions of the State Council of P.R.C. on Promoting the Sustainable and Healthy Development of Rare Earth Industry", regulate and standardize rare earth production order and accelerate the transformation of rare earth industry development pattern, the Ministry of Industry and Information Technology, Ministry of Supervision, Ministry of Environmental Protection, the State Administration of Taxation, the State Administration for Industry and Commerce and the State Administration of Work Safety jointly issued the "Notification on Carrying out the Special Rectification of Rare Earth Production Order Nationwide" and decided to carry out the special campaigns from 2011 August 1 to December 31.

  1. Fault Tolerant Variable Block Carry Skip Logic (VBCSL) using Parity Preserving Reversible Gates

    CERN Document Server

    Islam, Md Saiful; Begum, Zerina; Hafiz, Mohd Zulfiquar

    2010-01-01

    Reversible logic design has become one of the promising research directions in low power dissipating circuit design in the past few years and has found its application in low power CMOS design, digital signal processing and nanotechnology. This paper presents the efficient design approaches of fault tolerant carry skip adders (FTCSAs) and compares those designs with the existing ones. Variable block carry skip logic (VBCSL) using the fault tolerant full adders (FTFAs) has also been developed. The designs are minimized in terms of hardware complexity, gate count, constant inputs and garbage outputs. Besides of it, technology independent evaluation of the proposed designs clearly demonstrates its superiority with the existing counterparts.

  2. On the major Characteristics of Writing in Dreiser’s Sister Carrie

    Institute of Scientific and Technical Information of China (English)

    张含

    2014-01-01

    Dreiser’s Sister Carrie has been controverted for a long time. It is still consummate today and as alive and valid as when it was written. First, the description of the psychology plays an important role in revealing the personalities of the major characters and deepens the theme. The second is Dreiser’s usage of comparison. Finally Dreiser uses the method of realism like Balzac. Sister Carrie is the exact reflection and the mirror of the society. Its special characteristics and the realistic writing style start a new field in American literature.

  3. Surface barrier effect on magnetization of a current-carrying type-II superconductor

    Science.gov (United States)

    Genenko, Yu. A.; Freyhardt, H. C.

    2000-10-01

    Vortex penetration in and exit from ideal flux-filled current-carrying superconductors are studied in the frame of the modified Meissner state model accounting for the vortex interactions with the sample surface, transport current, external field and the other vortices inside the sample. The generalized Silsbee's rule is first formulated and the M- H diagram of ideal current-carrying superconductors in a parallel field is estimated which is irreversible due to the surface effect alone. In general, magnetic behaviour of superconductors is shown to be more reversible in the presence of a transport current.

  4. Clonal spread of blaOXA-72-carrying Acinetobacter baumannii sequence type 512 in Taiwan.

    Science.gov (United States)

    Kuo, Han-Yueh; Hsu, Po-Jui; Chen, Jiann-Yuan; Liao, Po-Cheng; Lu, Chia-Wei; Chen, Chang-Hua; Liou, Ming-Li

    2016-07-01

    This is the first report to show an insidious outbreak of armA- and blaOXA-72-carrying Acinetobacter baumannii sequence type 512 (ST512) at a study hospital in northern Taiwan. Multilocus sequence typing revealed that this was a ST512 clone. All of the isolates with ST512 carried a novel 12,056-bp repGR2 in combination with a repGR12-type plasmid. This plasmid, designated pAB-ML, had one copy of the blaOXA-72 gene that was flanked by XerC/XerD-like sites and conferred resistance to carbapenems.

  5. Designing of Modified Area Efficient Square Root Carry Select Adder(SQRT CSLA)

    OpenAIRE

    Priya Meshram; Prof.Mamta Sarode

    2015-01-01

    In the design of Integrated Circuits, The necessity of portable systems is increasing an area occupancy plays a vital role. Square Root Carry Select Adder (SQRT CSLA) is one of the fastest adders which is used in this data-processing processor to perform fast arithmetic functions. In this paper, an area-efficient square root carry select adder(SQRT CSLA design) by sharing Common Boolean logic term (CBL) is proposed The modified architecture has been developed using Binary to Excess-1 converte...

  6. Design of Modified Area Efficient Square Root Carry Select Adder (SQRT CSLA)

    OpenAIRE

    Priya Meshram; Prof.Mamta Sarode

    2015-01-01

    In the design of Integrated Circuits, The necessity of portable systems is increasing an area occupancy plays a vital role. Square Root Carry Select Adder (SQRT CSLA) is one of the fastest adders which is used in this data-processing processor to perform fast arithmetic functions. In this paper, an area-efficient square root carry select adder(SQRT CSLA design) by sharing Common Boolean logic term (CBL) is proposed The modified architecture has been developed using Binary to Excess-1 converte...

  7. Cuttings-carried theory and erosion rule in gas drilling horizontal well

    Directory of Open Access Journals (Sweden)

    Wei Na

    2014-01-01

    Full Text Available In gas horizontal drilling, the gas with cuttings will go through the annulus at high speed which will lead strong erosion to the drill tools. This paper proposes a cuttings-carried theory and modified the critical cuttings-carried model for the gas-solid flow. Meanwhile, the erosive energy is obtained through simulating the gas-solid mixture in different conditions. The study result has positive significance on the determination of reasonable injection volume by optimizing construction parameters of horizontal well in gas drilling.

  8. On the first tachinid fly (Diptera, Tachinidae carrying Asclepiadoideae pollinaria in the Neotropical Region

    Directory of Open Access Journals (Sweden)

    Silvio Shigueo Nihei

    2011-09-01

    Full Text Available On the first tachinid fly (Diptera, Tachinidae carrying Asclepiadoideae pollinaria in the Neotropical Region. This paper reports the first Neotropical Tachinidae species possibly associated to pollination of Asclepiadoideae: a female of Euacaulona sumichrasti Townsend, 1908 (Diptera, Tachinidae, Phasiinae, Trichopodini carrying pollinaria of Gonolobus parviflorus Decne., 1844 (Apocynaceae, Asclepiadoideae, Asclepiadeae: Gonolobinae attached to its proboscis. The fly specimen was collected in Paraguay, Departamento Canindeyú. The pollinarium is illustrated and described herein. This represents the first anthophilous record to G. parviflorus and to the genus.

  9. Low Power Modulo 2n+1 Adder Based on Carry Save Diminished-One Number System

    Directory of Open Access Journals (Sweden)

    Somayeh Timarchi

    2008-01-01

    Full Text Available Modulo 2n+1 adders find great applicability in several applications including RNS implementations. This paper presents a new number system called Carry Save Diminished-one for modulo 2n+1 addition and a novel addition algorithm for its operands. In this paper, we also present a novel architectures for designing modulo 2n+1 adders, based on parallel-prefix carry computation units. CMOS implementations reveal the superiority of the resulting adders against previously reported solutions in terms of implementation area and delay.

  10. The Conflict Between the Traditional Value and Reality In Sister Carrie

    Institute of Scientific and Technical Information of China (English)

    顾庆媛; 陈飞; 孙胜强; 常利娜; 张罗斌

    2009-01-01

    Theodore Dreiser relates a story of Carrie's rise from a poor country girl to a Broadway star in Sister Carrie.An attempt is rnade in this paper to analyze the cold society.Byway of analyzing this unequal and cruel reality to prove:in the world only the fittest can survive.the standards and requirements of morality are challenged and the traditional value is suspected.In the cold reality.any way that Can protect oneself or survivein the wodd is sensible,morality and traditional value are weak and mcaningless.

  11. THE ENTERPRISE - THE LEGAL FORM FOR CARRYING ON AN ACTIVITY HAVING A PROFESSIONAL NATURE

    Directory of Open Access Journals (Sweden)

    Stanciu D. C RPENARU

    2011-08-01

    Full Text Available The new Romanian Civil Code has institutionalised a new conception regarding the regulating system for civil and commercial legal relations. Thus, new concepts emerge to fit the new conception, concepts regarding to the persons, the professionals, and the carrying on of an organised and systematised activity that qualifies such activity as having a professional nature. As one can find the new civil code has changed the conception regarding the enterprise, as it resulted from the actual commercial code. The operation of an enterprise will represent the legal form of carrying on an activity having a professional nature.

  12. Carrying capacity for the electromagnetic suspension low-speed maglev train on the horizontal curve

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    Aiming at the lateral dislocation between the electromagnets and the rails on a horizontal curve,we investigated a single magnetic bogie of the maglev train in this paper.The magnetic levitation and guidance forces supplied by the suspension modules were deduced by the flux tube method.According to the dynamic equilibrium equations of the maglev train on the curved track with cant,several major factors that influence the carrying capacity were analyzed,and the formula of the carrying capacity was presented.The results provide a theoretical reference for the design of maglev train.

  13. First observation of photons carrying orbital angular momentum in undulator radiation.

    Science.gov (United States)

    Bahrdt, J; Holldack, K; Kuske, P; Müller, R; Scheer, M; Schmid, P

    2013-07-19

    Photon beams of 99 eV energy carrying orbital angular momentum (OAM) have been observed in the 2nd harmonic off-axis radiation of a helical undulator at the 3rd generation synchrotron radiation light source BESSY II. For detection, the OAM carrying photon beam was superimposed with a reference beam without OAM. The interference pattern, a spiral intensity distribution, was recorded in a plane perpendicular to the propagation direction. The orientation of the observed spiral structure is related to the helicity of the undulator radiation. Excellent agreement between measurements and simulations has been found.

  14. Very low cost stand-off suicide bomber detection system using human gait analysis to screen potential bomb carrying individuals

    Science.gov (United States)

    Greneker, Gene, III

    2005-05-01

    Individuals who carry bombs on their bodies and detonate those bombs in public places are a security problem. There is belief that suicide bombings currently used in the mid-east may spread to the United States if the organized terrorist groups operating in the United States are not identified and the cell members arrested. While bombs in vehicles are the primary method currently used to spread terror in Iraq, U. S. warfighters are starting to face suicide bombers. This may become more of the situation if a stand-off detection capability is developed for the vehicle bomb case. This paper presents a concept, that if developed and commercialized, could provide an inexpensive suicide bomber screening system that could be used to screen individuals approaching a checkpoint while the individual is still 500 to 1,000 feet from the checkpoint. The proposed system measures both the radar cross-section of the individual and the radar derived gait characteristics that are associated with individuals carrying a bomb on their body. GTRI researchers propose to use human gait characteristics, as detected by radar, to determine if a human subject who is carrying no visible load on the body is actually carrying a concealed load under their clothes. The use of radar gait as a metric for the detection (as opposed to a video system) of a suicide bomber is being proposed because detection of gait characteristics are thought to be less sensitive to where the bomb is located on the body, lighting conditions, and the fact that the legs may be shrouded in a robe. The detection of a bomb using radar gait analysis may also prove to be less sensitive to changing tactics regarding where the bomb is placed on the body. An inert suicide bomb vest was constructed using water pipes to simulate the explosive devices. Wiring was added to simulated detonators. The vest weighs approximately 35 pounds. Radar data was taken on the volunteer subject wearing the vest that simulated the suicide bomb. This

  15. Reduced fertility after the crash of a U.S. bomber carrying nuclear weapons?

    DEFF Research Database (Denmark)

    Juel, K

    1995-01-01

    A register-based study was performed to elucidate whether workers employed on the Thule air base in the clean-up period after the crash of a U.S. B-52 bomber carrying nuclear bombs had reduced fertility, as measured by the numbers of liveborn children. The highest birth rates were among 25-34-year...

  16. Weapon Carrying in Israeli Schools: The Contribution of Individual and School Factors

    Science.gov (United States)

    Khoury-Kassabri, Mona; Astor, Ron Avi; Benbenishty, Rami

    2007-01-01

    The present study employed an ecological perspective to examine the relative predictive power of individual and school contextual factors on weapon carrying at school. The study is based on a nationally representative sample of 10,400 students in Grades 7 through 11 in 162 schools across Israel. Hierarchical logistic modeling examined the…

  17. 34 CFR 413.3 - What kinds of activities are carried out?

    Science.gov (United States)

    2010-07-01

    ... EDUCATION General § 413.3 What kinds of activities are carried out? The Secretary provides a grant or... pursuant to section 404(d) of the Act, such other topics as the Secretary may designate. (2) The National... of minorities and women for leadership roles in vocational education. (b) Dissemination and training...

  18. Discurso del Ing. Rolando Carrión Muñoz

    OpenAIRE

    Carrión Muñoz, Rolando; Universidad Nacional Mayor de San Marcos

    2014-01-01

    Discurso del Ing. Rolando Carrión Muñoz, con motivo del reconocimiento de la calidad académica otorgada por el Consejo Nacional de Acreditación Universitaria, a la EAP de Ingeniería Industrial de la UNMSM (24 de abril de 2014)

  19. 36 CFR 5.4 - Commercial passenger-carrying motor vehicles.

    Science.gov (United States)

    2010-07-01

    ... motor vehicles. 5.4 Section 5.4 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR COMMERCIAL AND PRIVATE OPERATIONS § 5.4 Commercial passenger-carrying motor vehicles. (a) The commercial transportation of passengers by motor vehicles except as authorized under a contract...

  20. Discurso del Ing. Rolando Carrión Muñoz

    OpenAIRE

    Carrión Muñoz, Rolando; Universidad Nacional Mayor de San Marcos

    2014-01-01

    Discurso del Ing. Rolando Carrión Muñoz, con motivo del reconocimiento de la calidad académica otorgada por el Consejo Nacional de Acreditación Universitaria, a la EAP de Ingeniería Industrial de la UNMSM (24 de abril de 2014)

  1. Identification and characterization of a Zea mays line carrying a transposon-tagged ENOD40

    NARCIS (Netherlands)

    Compaan, B.; Ruttink, T.; Albrecht, C.; Meeley, R.; Bisseling, T.; Franssen, H.G.J.M.

    2003-01-01

    In Zea mays, two ENOD40 homologous were identified that show only 30% of sequence homology to each other. We identified line e40-mum1 carrying a Mu transposon inserted in ZmENOD40-1, the maize gene that has the highest homology to leguminous ENOD40. The insertion causes a dramatic reduction of the Z

  2. Successfully carrying out complex learning tasks through guiding teams’ qualitative and quantitative reasoning

    NARCIS (Netherlands)

    Slof, Bert; Erkens, Gijsbert; Kirschner, Paul A.; Janssen, Jeroen; Jaspers, Jos

    2011-01-01

    Slof, B., Erkens, G., Kirschner, P. A., Janssen, J., & Jaspers, J. G. M. (2012). Successfully carrying out complex learning tasks through guiding teams' qualitative and quantitative reasoning. Instructional Science, 40, 623-643. DOI: 10.1007/s11251-011-9185-2

  3. Wie carrière maakt mag het zeggen : Loopbaanconcepten in subjectief perspectief

    NARCIS (Netherlands)

    N.A.F.M. Schreiner (Norman)

    2008-01-01

    textabstractCarrière maken wordt in het alledaagse spraakgebruik niet zelden vereenzelvigd met geleidelijke klim op de hiërarchische ladder van de organisatie. Er zijn echter ook andere vormen van progressie in een loopbaan te onderscheiden, vormen die niet altijd aandacht ondervinden in discussies

  4. Successfully carrying out complex learning tasks through guiding teams’ qualitative and quantitative reasoning

    NARCIS (Netherlands)

    Slof, Bert; Erkens, Gijsbert; Kirschner, Paul A.; Janssen, Jeroen; Jaspers, Jos

    2011-01-01

    Slof, B., Erkens, G., Kirschner, P. A., Janssen, J., & Jaspers, J. G. M. (2012). Successfully carrying out complex learning tasks through guiding teams' qualitative and quantitative reasoning. Instructional Science, 40, 623-643. DOI: 10.1007/s11251-011-9185-2

  5. Performance Enhancement of Multi-Output Carry Look-Ahead Cmos Csa

    Directory of Open Access Journals (Sweden)

    K. Ram Babu,

    2014-06-01

    Full Text Available Carry Select Adder (CSA is solitary of the best ever adders worn in numerous data-processing processors to complete speedy arithmetic functions. From the construction of the CSA, it is lucid that there is scope for sinking the vicinity and clout burning up in the CSA. This adder is based on both a static and compact multi-output carry look-ahead (CSA circuitof highly area-efficient CMOS carry-select adder (CSA with a regular and iterative-shared transistor structure very suitable for implementation in VLSI and a very simple select circuit. Comparisons with other representative 32-bit CSAs show that the proposed adder reduces the area. This paper uses a easy and proficient gate-level amendment to drastically diminish the vicinity and power of the CSA. Based on this modification different square-root CSA (SQRT CSA constructions have been developed and compared with the customary square-root architecture. The projected intend has reduced vicinity and power as compared with the regular Square Root CSA with only a slight increase in the delay. In this paper, conventional CSA is compared with Modified Carry select adder (MCSA, Regular Square Root CSLA (SQRT CSA, Modified SQRT CSA and Proposed SQRT CSA in terms of area, delay and power consumption. The result analysis shows that the proposed structure is better than the conventional CSA.

  6. 34 CFR 412.30 - What additional activities must be carried out by Curriculum Coordination Centers?

    Science.gov (United States)

    2010-07-01

    ... Curriculum Coordination Centers? 412.30 Section 412.30 Education Regulations of the Offices of the Department... NETWORK FOR CURRICULUM COORDINATION IN VOCATIONAL AND TECHNICAL EDUCATION What Conditions Must Be Met After An Award? § 412.30 What additional activities must be carried out by Curriculum Coordination...

  7. 33 CFR 157.172 - Limitations on grades of crude oil carried.

    Science.gov (United States)

    2010-07-01

    ... § 157.10c(b)(2) does not have segregated ballast tanks or dedicated clean ballast tanks that meet § 157... HOMELAND SECURITY (CONTINUED) POLLUTION RULES FOR THE PROTECTION OF THE MARINE ENVIRONMENT RELATING TO TANK VESSELS CARRYING OIL IN BULK Crude Oil Washing (COW) System on Tank Vessels Cow Operations §...

  8. TNF-alpha levels are not increased in inflamed patients carrying the CCR5 deletion 32

    NARCIS (Netherlands)

    Muntinghe, Friso L. H.; Carrero, Juan Jesus; Navis, Gerjan; Stenvinkel, Peter

    2011-01-01

    Background and aims: Recently we reported on a genetically predisposed protection from C-reactive protein (CRP) related mortality in dialysis patients carrying the functional CC-chemokine receptor 5 deletion 32 allele (CCR5 Delta 32) mutation. Since CCR5 Delta 32 is associated with a less pro-inflam

  9. Proteinase 3 carries small unusual carbohydrates and associates with αlpha-defensins

    DEFF Research Database (Denmark)

    Zoega, Morten; Ravnsborg, Tina; Højrup, Peter

    2012-01-01

    with carbohydrates at Asn 102 and 147 carrying unusual small moieties indicating heavy processing. Mass spectrometric analysis and immuno blotting revealed strong association of highly purified PR3 with α-defensins and oligomers hereof. Irreversible inhibition of PR3 by α1-antitrypsin did not affect its association...

  10. Influence and selection processes in weapon carrying during adolescence : The roles of status, aggression, and vulnerability

    NARCIS (Netherlands)

    Dijkstra, Jan; Lindenberg, Siegwart; Veenstra, Rene; Steglich, Christian; Isaacs, Jenny; Card, Noel A.; Hodges, Ernest V. E.

    The role of peers in weapon carrying (guns, knives, and other weapons) inside and outside the school was examined in this study. Data stem from a longitudinal study of a high-risk sample of male students (7th to 10th grade; N = 167) from predominantly Hispanic low-socio-economic-status schools in

  11. Weapon Carrying in Israeli Schools: The Contribution of Individual and School Factors

    Science.gov (United States)

    Khoury-Kassabri, Mona; Astor, Ron Avi; Benbenishty, Rami

    2007-01-01

    The present study employed an ecological perspective to examine the relative predictive power of individual and school contextual factors on weapon carrying at school. The study is based on a nationally representative sample of 10,400 students in Grades 7 through 11 in 162 schools across Israel. Hierarchical logistic modeling examined the…

  12. Charged Particle Dynamics in the Magnetic Field of a Long Straight Current-Carrying Wire

    Science.gov (United States)

    Prentice, A.; Fatuzzo, M.; Toepker, T.

    2015-01-01

    By describing the motion of a charged particle in the well-known nonuniform field of a current-carrying long straight wire, a variety of teaching/learning opportunities are described: 1) Brief review of a standard problem; 2) Vector analysis; 3) Dimensionless variables; 4) Coupled differential equations; 5) Numerical solutions.

  13. Efficient expansion of human keratinocyte stem/progenitor cells carrying a transgene with lentiviral vector

    Science.gov (United States)

    2013-01-01

    Introduction The development of an appropriate procedure for lentiviral gene transduction into keratinocyte stem cells is crucial for stem cell biology and regenerative medicine for genetic disorders of the skin. However, there is little information available on the efficiency of lentiviral transduction into human keratinocyte stem/progenitor cells and the effects of gene transduction procedures on growth potential of the stem cells by systematic assessment. Methods In this study, we explored the conditions for efficient expansion of human keratinocyte stem/progenitor cells carrying a transgene with a lentiviral vector, by using the culture of keratinocytes on a feeder layer of 3 T3 mouse fibroblasts. The gene transduction and expansion of keratinocytes carrying a transgene were analyzed by Western blotting, quantitative PCR, and flow cytometry. Results Polybrene (hexadiamine bromide) markedly enhanced the efficiency of lentiviral gene transduction, but negatively affected the maintenance of the keratinocyte stem/progenitor cells at a concentration higher than 5 μg/ml. Rho-assiciated kinase (ROCK) inhibitor Y-27632, a small molecule which enhanced keratinocyte proliferation, significantly interfered with the lentiviral transduction into cultured human keratinocytes. However, a suitable combination of polybrene and Y-27632 effectively expanded keratinocytes carrying a transgene. Conclusions This study provides information for effective expansion of cultured human keratinocyte stem/progenitor cells carrying a transgene. This point is particularly significant for the application of genetically modified keratinocyte stem/progenitor stem cells in regenerative medicine. PMID:24406242

  14. 46 CFR 25.45-1 - Heating and lighting systems on vessels carrying passengers for hire.

    Science.gov (United States)

    2010-10-01

    ...) Alcohol, solid, (2) Alcohol, liquid, combustible, (3) Fuel oil, No. 1, No. 2, or No. 3, (4) Kerosene, (5.../4” to form a pan. (2) Fuel tanks must be— (i) Separated from the stove that they serve; (ii) Mounted... on vessels carrying passengers for hire. (a) No fuel may be used in any heating or lighting system...

  15. Evaluation of a hand carried cardiac ultrasound device in an outpatient cardiology clinic

    NARCIS (Netherlands)

    E.C. Vourvouri (Eleni); D. Poldermans (Don); G.E. Parharidis; J.R.T.C. Roelandt (Jos); J.W. Deckers (Jaap)

    2005-01-01

    textabstractOBJECTIVE: To determine the diagnostic potential of a hand carried cardiac ultrasound (HCU) device (OptiGo, Philips Medical Systems) in a cardiology outpatient clinic and to compare the HCU diagnosis with the clinical diagnosis and diagnosis with a full featured standar

  16. 77 FR 59408 - Finding of Equivalence; Alternate Pressure Relief Valve Settings on Certain Vessels Carrying...

    Science.gov (United States)

    2012-09-27

    ... SECURITY Coast Guard Finding of Equivalence; Alternate Pressure Relief Valve Settings on Certain Vessels... Coast Guard announces the availability of CG-ENG Policy Letter 04-12, ``Alternative Pressure Relief Valve Settings on Vessels Carrying Liquefied Gases in Bulk in Independent Type B and Type C...

  17. Thermodynamics of micellization of cholic acid based facial amphiphiles carrying three permanent ionic head groups

    NARCIS (Netherlands)

    Willemen, H.M.; Marcelis, A.T.M.; Sudhölter, E.J.R.

    2003-01-01

    This paper describes a series of cholic acid based facial amphiphiles carrying three ionic headgroups. Their micellization behavior in water was studied as a function of spacer length and alkyl tail length: both were found to have a small influence on the critical micellization concentration (cmc).

  18. 36 CFR 702.8 - Use and carrying of food and beverages in Library buildings.

    Science.gov (United States)

    2010-07-01

    ... areas where there exists significant risk to Library materials or property or where there may result a... beverages in Library buildings. 702.8 Section 702.8 Parks, Forests, and Public Property LIBRARY OF CONGRESS CONDUCT ON LIBRARY PREMISES § 702.8 Use and carrying of food and beverages in Library...

  19. Factors affecting the environmental carrying capacity of a freshwater tropical lake system.

    Science.gov (United States)

    Mullakkezhil Reghunathan, Vishnuprasad; Joseph, Sabu; Warrier, C Unnikrishnan; Hameed, A Shahul; Albert Moses, Sheela

    2016-11-01

    Environmental carrying capacity is a measure of competence of a lake to accommodate pollution inputs without degrading water quality. In the research reported here, we identified the factors influencing the environmental carrying capacity of Vellayani Lake or VL (a typical tropical freshwater lake), Thiruvananthapuram, Kerala State, India. R-mode factor analysis is used to identify the factors controlling the carrying capacity of the lake, whereas hierarchical cluster analysis (HCA) helped to classify the lake. The carrying capacity of the lake is low with respect to alkalinity, due to ion deficiency, and is potentially reactive to sudden changes in pH. Eutrophic condition exists in the entire lake system. Acidic factor, mineralization factor, fertilizer factor (P & K), evaporation factor and organic pollution factor are the controllers of VL water quality during the pre-monsoon period. The same factors (but not evaporation factor) and an additional runoff factor control the water quality during monsoon. In the post-monsoon, the aforesaid factors (other than runoff, alkalinity) and soil erosion factor influence the water quality. Hence, managers of the lake system need to also focus on combating acidic factor during pre- and post-monsoons and runoff during monsoon. Smaller areal extent and shallow depth of VL, reduced outflow from it, less rainfall, presence of lateritic rock and soil and absence of limestone strata in the catchment are the chief elements affecting the acidic factor of Vellayani Lake.

  20. EFFICIENT, INTEGRATED TRANSPORT SYSTEM KEY TO PORT'S SUCCESS:Houston Sufficient support infrastructure, carrying capacity needed

    Institute of Scientific and Technical Information of China (English)

    ALAN DANIELS

    2005-01-01

    @@ An efficient, integrated transport system iskey to the Port of Vancouver s success. "There are many ways that we can optimizethe efficiency and carrying capacity of ourtransportation infrastructure in Canada: throughtechnology, by working together, by thinkingdifferently," said Captain Gordon Houston,President & CEO of the Vancouver Port Authority.

  1. The Carrying Capacity of Public Wild Land Recreation Areas: Evaluation of Alternative Measures

    Science.gov (United States)

    Greist, David A.

    1976-01-01

    Carrying capacity (the use level at which total satisfactions or benefits are mazimized) is not equatable to highest-use levels, since some visitors to recreational areas desire solitude and undisturbed environment--for these, an alternative definition for "capacity" should take into consideration the use level demanded after considering costs.…

  2. A classical to quantum optical network link for orbital angular momentum carrying light

    CERN Document Server

    Zhou, Zhi-Yuan; Ding, Dong-Sheng; Zhang, Wei; Shi, Shuai; Shi, Bao-Sen; Guo, Guang-Can

    2015-01-01

    Light with orbital angular momentum (OAM) has great potentials in both classical and quantum optical communications such as enhancing the transmission capacity of a single communication channel because of its unlimited dimensions. Based on OAM conservation in second order nonlinear interaction processes, we create a classical to quantum optical network link in OAM degree of freedoms of light via sum frequency generation (SFG) following by a spontaneous parametric down conversion (SPDC). A coherent OAM-carrying beams at telecom wavelength 1550nm is up-converted to 525.5nm OAM-carrying beams in the first crystal, then up-converted OAM-carrying beam is used to pump a second crystal to generate non-degenerate OAM entangled photon pairs at 795nm and 1550nm. By switching the OAM carries by the classical party, the OAM correlation in the quantum party is shifted. High OAM entanglements in two dimensional subspaces are verified. This primary study enables to build a hybrid optical communication network contains both ...

  3. Fuzzy Comprehensive Evaluation Model for Water Resources Carrying Capacity in Tarim River Basin, Xinjiang, China

    Institute of Scientific and Technical Information of China (English)

    MENG Lihong; CHEN Yaning; LI Weihong; ZHAO Ruifeng

    2009-01-01

    This paper explores the method of comprehensive evaluation of water resources carrying capacity and sets up an evaluation model applying the fuzzy comprehensive evaluation method. Based on the data of nature, society, economics and water resources of the Tarim River Basin in 2002, we evaluated the water resources carrying capacity of the basin by means of the model. The results show that the comprehensive grades are 0.438 and 0.454 for Aksu and Kashi prefectures respectively, where the current water resources exploitation and utilization has reached a relative high degree and there is only a very limited water carrying capacity, 0.620 for Kizilsu Kirgiz Autonomous Prefecture, where water resources carrying capacity is much higher, and in between for Hotan Prefecture and Bayingolin Mongolian Autonomous Prefecture. As a whole, the comprehensive grade of the Tarim River Basin is 0.508 and the current water resources exploitation and utilization has reached a relative high degree. Thus, we suggest that the integrated management of the water resources in the basin should be strengthened in order to utilize water resources scientifically and sustainably.

  4. Ecological Footprints and Appropriated Carrying Capacity: Measuring the Natural Capital Requirements of the Human Economy.

    Science.gov (United States)

    Ress, William E.; Wackernagel, Mathis

    1996-01-01

    Contrasts conventional economic rationality with economic principles. Develops an empirical approach based on a reinterpretation of carrying capacity that can account for technological advances and trade. Discusses the necessity of diverting much of the present consumption to investment in the maintenance of natural capital stocks. (AIM)

  5. Comment on "Invasive Harlequin Ladybird Carries Biological Weapons Against Native Competitors"

    NARCIS (Netherlands)

    Jong, de P.W.; Lenteren, van J.C.; Raak-van den Berg, C.L.

    2013-01-01

    We comment on the implications that Vilcinskas et al. (Reports, 17 May 2013, p. 862) attach to the finding that the exotic, invasive ladybird Harmonia axyridis carries microsporidia to which this species is insensitive but that is lethal to species that are native to the invaded areas. The authors s

  6. Carrying Position Independent User Heading Estimation for Indoor Pedestrian Navigation with Smartphones

    Directory of Open Access Journals (Sweden)

    Zhi-An Deng

    2016-05-01

    Full Text Available This paper proposes a novel heading estimation approach for indoor pedestrian navigation using the built-in inertial sensors on a smartphone. Unlike previous approaches constraining the carrying position of a smartphone on the user’s body, our approach gives the user a larger freedom by implementing automatic recognition of the device carrying position and subsequent selection of an optimal strategy for heading estimation. We firstly predetermine the motion state by a decision tree using an accelerometer and a barometer. Then, to enable accurate and computational lightweight carrying position recognition, we combine a position classifier with a novel position transition detection algorithm, which may also be used to avoid the confusion between position transition and user turn during pedestrian walking. For a device placed in the trouser pockets or held in a swinging hand, the heading estimation is achieved by deploying a principal component analysis (PCA-based approach. For a device held in the hand or against the ear during a phone call, user heading is directly estimated by adding the yaw angle of the device to the related heading offset. Experimental results show that our approach can automatically detect carrying positions with high accuracy, and outperforms previous heading estimation approaches in terms of accuracy and applicability.

  7. Status clarification and disposal of Carrière’s ivy names

    Directory of Open Access Journals (Sweden)

    Severiano Nava, Herminio

    2016-06-01

    Full Text Available Carrière in 1890 published 34 names and 33 descriptions of a collection of live ivy plants. In this article we present the analysis of his work from a nomenclatural perspective. As a result, the legitimacy and even the validity of specific and some of the infraspecific names published in the work are questioned. In addition to this, and considering the benefits on keeping the nomenclatural stability, Hedera azorica Carrière, is proposed as a nomen conservandum.Carrière en 1890 publicó 34 nombres y 33 descripciones de una colección de plantas vivas de hiedra. En este artículo se presenta el análisis de su obra desde una perspectiva nomenclatural. Como resultado, la legitimidad e incluso la validez de algunos de los nombres específicos e infraespecíficos publicados en la obra son puestas en tela de juicio. Además, teniendo en cuenta los beneficios de mantener la estabilidad nomenclatural, Hedera azorica Carrière se propone como nomen conservandum.

  8. 42 CFR 71.56 - African rodents and other animals that may carry the monkeypox virus.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false African rodents and other animals that may carry... HUMAN SERVICES QUARANTINE, INSPECTION, LICENSING FOREIGN QUARANTINE Importations § 71.56 African rodents... import or attempt to import any rodents, whether dead or alive, that were obtained, directly...

  9. Association of Parental Awareness of Using Schoolbags with Musculoskeletal Symptoms and Carrying Habits of Schoolchildren

    Science.gov (United States)

    Dianat, Iman; Karimi, Mohammad Ali

    2014-01-01

    The association between parental awareness of using schoolbags and the occurrence of musculoskeletal symptoms and carrying habits of children was investigated in a cross-sectional study in Tabriz, Iran. Data on 454 students aged 11-14 years and their parents (n = 358) were analyzed. The awareness of the recommended weight limit, appropriate method…

  10. High-level methodology for carrying out combined red and blue teams

    CSIR Research Space (South Africa)

    Veerasamy, N

    2009-12-01

    Full Text Available This paper proposes a combined Red and Blue Team Methodology to guide the process of carrying out such security auditing and penetration testing tasks. Red and Blue Teams consist of various security auditing and penetration testing tasks which serve...

  11. Conjugal mobilization of the mega element carrying mef(E) from Streptococcus salivarius to Streptococcus pneumoniae.

    Science.gov (United States)

    Santagati, Maria; Lupo, Agnese; Scillato, Marina; Di Martino, Andrea; Stefani, Stefania

    2009-01-01

    We report the isolation and characterization of an unusual strain of Streptococcus salivarius, 3C30, displaying both the macrolide-lincosamide-streptogramin B and the tetracycline resistance phenotypes. It harbours the mef(E), erm(B), and tet(M) genes carried by different genetic elements. The genetic element carrying mef(E), named mega, was investigated by long PCR and sequencing, while the presence of the Tn3872-like element, carrying tet(M) and erm(B), was demonstrated by sequencing of both the int-xis-Tn and the fragment between the two resistance genes. In strain 3C30 the mega element is 5388 bp in size and its nucleotide sequence is identical to that of the element described previously in S. salivarius, with the exception of a 912 bp deletion at the left end. The composite Tn3872-like element appeared to be nonconjugative while the mega element was transferred by conjugation to Streptococcus pneumoniae. It was, however, impossible to transfer it again from these transconjugants to other strains. In addition, only in the 3C30 strain did mega form circular structures, as identified by real-time PCR. In conclusion, we found a clinical strain of S. salivarius carrying both mega and Tn3872-like genetic elements. Mega is transferable by conjugation to S. pneumoniae but it is not transferable again from the transconjugants, suggesting a possible mobilization by recombinases of the coresident Tn3872-like transposon.

  12. A simplified model predicting the weight of the load carrying beam in a wind turbine blade

    DEFF Research Database (Denmark)

    Mikkelsen, Lars Pilgaard

    2016-01-01

    to predict the weight of the load carrying beam when using glassfibre reinforced polymers, carbon fibre reinforced polymers or an aluminium alloy as the construction material. Thereby, it is found that the weight of a glass fibre wind turbine blade is increased from 0.5 to 33 tons when the blade length grows...

  13. AIHEC CEO Carrie Billy Explains What Drives Her as Public Servant, Mother

    Science.gov (United States)

    Schilling, Vincent

    2009-01-01

    This article profiles American Indian Higher Education Consortium's (AIHEC) President and CEO Carrie Billy. Billy's experience in law, a U.S. senator's office, and in the legislative and administrative branches of government is crucial for an institution that relies on state and federal legislative processes to gain funding and support. AIHEC is a…

  14. Pyrosequencing reveal distinct bacteria are carried in different wind eroded sediments from the same soil

    Science.gov (United States)

    Little is known about the microbial communities carried in wind-eroded sediments from various soil types and land management systems. A novel technique, named pyrosequencing, promises to expand our understanding of the vast microbial diversity of soils and eroded sediments as it can sequence between...

  15. Anthropometric Measurements as Predictors of the Degree of Carrying Angle in College Baseball Players

    Science.gov (United States)

    Cox, Chris

    2011-01-01

    Scope and Method of Study: The goal of this study was to examine whether or not height, shoulder range of motion, hip width, shoulder width, and pitching experience were predictors for increased carrying angle of the throwing side. The premise of the study is based on an assumption that valgus extension overload produces tensile strain on the…

  16. Analyzing of Sister Carrie's Independence Process from the Perspective of Feminism

    Institute of Scientific and Technical Information of China (English)

    姜新新

    2015-01-01

    "Sister Carrie" is published when the American society is in the transition from traditional industry to modern industry.Modern industrial not only provide opportunity to the development of city,but also offer some employment opportunities to the people,while the survival pressure for living is also increased.People's thought also undergo a tremendous change.They even feel puzzled andconfused.

  17. Influence and selection processes in weapon carrying during adolescence : The roles of status, aggression, and vulnerability

    NARCIS (Netherlands)

    Dijkstra, Jan; Lindenberg, Siegwart; Veenstra, Rene; Steglich, Christian; Isaacs, Jenny; Card, Noel A.; Hodges, Ernest V. E.

    2010-01-01

    The role of peers in weapon carrying (guns, knives, and other weapons) inside and outside the school was examined in this study. Data stem from a longitudinal study of a high-risk sample of male students (7th to 10th grade; N = 167) from predominantly Hispanic low-socio-economic-status schools in th

  18. Carrying Position Independent User Heading Estimation for Indoor Pedestrian Navigation with Smartphones.

    Science.gov (United States)

    Deng, Zhi-An; Wang, Guofeng; Hu, Ying; Cui, Yang

    2016-05-11

    This paper proposes a novel heading estimation approach for indoor pedestrian navigation using the built-in inertial sensors on a smartphone. Unlike previous approaches constraining the carrying position of a smartphone on the user's body, our approach gives the user a larger freedom by implementing automatic recognition of the device carrying position and subsequent selection of an optimal strategy for heading estimation. We firstly predetermine the motion state by a decision tree using an accelerometer and a barometer. Then, to enable accurate and computational lightweight carrying position recognition, we combine a position classifier with a novel position transition detection algorithm, which may also be used to avoid the confusion between position transition and user turn during pedestrian walking. For a device placed in the trouser pockets or held in a swinging hand, the heading estimation is achieved by deploying a principal component analysis (PCA)-based approach. For a device held in the hand or against the ear during a phone call, user heading is directly estimated by adding the yaw angle of the device to the related heading offset. Experimental results show that our approach can automatically detect carrying positions with high accuracy, and outperforms previous heading estimation approaches in terms of accuracy and applicability.

  19. On the flexural vibration of an elastic plate carrying a concentrated mass

    Energy Technology Data Exchange (ETDEWEB)

    Sadiku, S. (Federal Univ. of Technology, Minna (Nigeria). Dept. of Civil Engineering)

    1989-12-01

    The dynamic response of an elastic plate carrying a concentrated mass is analysed. Despite the presence of a singular mass distribtion function, a rigorous analysis leading to a closed-form solution in the form of an infinite series has been made. By developing Green's function for the associated partial differential equation, any form of dynamic excitation is easily considered. (orig.).

  20. Identification and characterization of a Zea mays line carrying a transposon-tagged ENOD40

    NARCIS (Netherlands)

    Compaan, B.; Ruttink, T.; Albrecht, C.; Meeley, R.; Bisseling, T.; Franssen, H.G.J.M.

    2003-01-01

    In Zea mays, two ENOD40 homologous were identified that show only 30% of sequence homology to each other. We identified line e40-mum1 carrying a Mu transposon inserted in ZmENOD40-1, the maize gene that has the highest homology to leguminous ENOD40. The insertion causes a dramatic reduction of the

  1. In vivo characteristics of targeted drug-carrying filamentous bacteriophage nanomedicines

    Directory of Open Access Journals (Sweden)

    Vaks Lilach

    2011-12-01

    Full Text Available Abstract Background Targeted drug-carrying phage nanomedicines are a new class of nanomedicines that combines biological and chemical components into a modular nanometric drug delivery system. The core of the system is a filamentous phage particle that is produced in the bacterial host Escherichia coli. Target specificity is provided by a targeting moiety, usually an antibody that is displayed on the tip of the phage particle. A large drug payload is chemically conjugated to the protein coat of the phage via a chemically or genetically engineered linker that provides for controlled release of the drug after the particle homed to the target cell. Recently we have shown that targeted drug-carrying phage nanomedicines can be used to eradicate pathogenic bacteria and cultured tumor cells with great potentiation over the activity of the free untargeted drug. We have also shown that poorly water soluble drugs can be efficiently conjugated to the phage coat by applying hydrophilic aminoglycosides as branched solubility-enhancing linkers. Results With an intention to move to animal experimentation of efficacy, we tested anti-bacterial drug-carrying phage nanomedicines for toxicity and immunogenicity and blood pharmacokinetics upon injection into mice. Here we show that anti-bacterial drug-carrying phage nanomedicines that carry the antibiotic chloramphenicol conjugated via an aminoglycoside linker are non-toxic to mice and are greatly reduced in immunogenicity in comparison to native phage particles or particles to which the drug is conjugated directly and are cleared from the blood more slowly in comparison to native phage particles. Conclusion Our results suggest that aminoglycosides may serve as branched solubility enhancing linkers for drug conjugation that also provide for a better safety profile of the targeted nanomedicine.

  2. Patients Carrying 9q31.1-q32 Deletion Share Common Features with Cornelia de Lange Syndrome

    Directory of Open Access Journals (Sweden)

    Ruixue Cao

    2015-01-01

    Full Text Available Background: Cornelia de Lange Syndrome (CdLS is a rare but severe clinically heterogeneous developmental disorder characterized by facial dysmorphia, growth and cognitive retardation, and abnormalities of limb development. Objectives: To determine the pathogenesis of a patient with CdLS. Methods: We studied a patient with CdLS by whole exome sequencing, karyotyping and Agilent CGH Array. The results were confirmed by quantitative real-time PCR analysis of the patient and her parents. Further comparison of our patient and cases with partially overlapping deletions retrieved from the literature and databases was undertaken. Results: Whole exome sequencing had excluded the mutation of cohesion genes such as NIPBL,SMC1A and SMC3. The result of karyotyping showed a deletion of chromosome 9q31.1-q32 and the result of Agilent CGH Array further displayed a 12.01-Mb region of deletion at chromosome bands 9q31.1-q32. Reported cases with the deletion of 9q31.1-q32 share similar features with our CdLS patient. One of the genes in the deleted region, SMC2, belongs to the Structural Maintenance of Chromosomes (SMC family and regulates gene expression and DNA repair. Conclusions: Patients carrying the deletion of 9q31.1-q32 showed similar phenotypes with CdLS.

  3. Patients carrying 9q31.1-q32 deletion share common features with Cornelia de Lange Syndrome.

    Science.gov (United States)

    Cao, Ruixue; Pu, Tian; Fang, Shaohai; Long, Fei; Xie, Jing; Xu, Yuejuan; Chen, Sun; Sun, Kun; Xu, Rang

    2015-01-01

    Cornelia de Lange Syndrome (CdLS) is a rare but severe clinically heterogeneous developmental disorder characterized by facial dysmorphia, growth and cognitive retardation, and abnormalities of limb development. To determine the pathogenesis of a patient with CdLS. We studied a patient with CdLS by whole exome sequencing, karyotyping and Agilent CGH Array. The results were confirmed by quantitative real-time PCR analysis of the patient and her parents. Further comparison of our patient and cases with partially overlapping deletions retrieved from the literature and databases was undertaken. Whole exome sequencing had excluded the mutation of cohesion genes such as NIPBL,SMC1A and SMC3. The result of karyotyping showed a deletion of chromosome 9q31.1-q32 and the result of Agilent CGH Array further displayed a 12.01-Mb region of deletion at chromosome bands 9q31.1-q32. Reported cases with the deletion of 9q31.1-q32 share similar features with our CdLS patient. One of the genes in the deleted region, SMC2, belongs to the Structural Maintenance of Chromosomes (SMC) family and regulates gene expression and DNA repair. Patients carrying the deletion of 9q31.1-q32 showed similar phenotypes with CdLS. © 2015 S. Karger AG, Basel.

  4. Low levels of the reverse transactivator fail to induce target transgene expression in vascular smooth muscle cells.

    Directory of Open Access Journals (Sweden)

    Nikenza Viceconte

    Full Text Available Hutchinson-Gilford progeria syndrome (HGPS is a genetic disease with multiple features that are suggestive of premature aging. Most patients with HGPS carry a mutation on one of their copies of the LMNA gene. The LMNA gene encodes the lamin A and lamin C proteins, which are the major proteins of the nuclear lamina. The organs of the cardiovascular system are amongst those that are most severely affected in HGPS, undergoing a progressive depletion of vascular smooth muscle cells, and most children with HGPS die in their early teens from cardio-vascular disease and other complications from atherosclerosis. In this study, we developed a transgenic mouse model based on the tet-ON system to increase the understanding of the molecular mechanisms leading to the most lethal aspect of HGPS. To induce the expression of the most common HGPS mutation, LMNA c.1824C>T; p.G608G, in the vascular smooth muscle cells of the aortic arch and thoracic aorta, we used the previously described reverse tetracycline-controlled transactivator, sm22α-rtTA. However, the expression of the reverse sm22α-transactivator was barely detectable in the arteries, and this low level of expression was not sufficient to induce the expression of the target human lamin A minigene. The results from this study are important because they suggest caution during the use of previously functional transgenic animal models and emphasize the importance of assessing transgene expression over time.

  5. [Mating success and courtship ritual in strains of Drosophila melanogaster carrying mutation flamenco].

    Science.gov (United States)

    Romanova, L G; Romanova, N I; Subocheva, E A; Kim, A I

    2000-04-01

    Mating success was examined in groups of Drosophila melanogaster carrying mutation flamMS (SS, MSn1-2, and MSn1-3) and in wild-type flies. The proportion of normally copulating males was significantly lower in the mutant strains. The reduction in mating efficiency was caused by changes in male behavior rather than in female attractiveness. Individual analyses showed that male mating behavior in strains carrying flamMS was qualitatively and quantitatively different from that in the wild-type strain Canton S. The proportion of males that performed consecutive courtship stages was significantly lower in the mutant strains. The sequence and duration of some courtship stages (in particular, orientation and wing vibration) in mutant flies was shown to be altered. The significance of the flamenco locus in regulation of processes occurring at the organismal level are discussed.

  6. [Some behavioral features in Drosophila melanogaster lines carrying a flamenco gene mutation].

    Science.gov (United States)

    Subocheva, E A; Romanova, L G; Romanova, N I; Kim, A I

    2001-11-01

    Olfactory sensitivity and locomotor activity was assayed in Drosophila melanogaster strains carrying a mutation of the flamenco gene, which controls transposition of the mobile genetic element 4 (MGE4) retrotransposon the gypsy mobile element. A change in olfactory sensitivity was detected. The reaction to the odor of acetic acid was inverted in flies of the mutator strain (MS), which carried the flam mutation and active MGE4 copies and were characterized by genetic instability. Flies of the genetically unstable strains displayed a lower locomotor activity. The behavioral changes in MS flies can be explained by the pleiotropic effect of the flam mutation or by insertion mutations which arise in behavior genes as a result of genome destabilization by MGE4.

  7. Assessing the Social Carrying Capacity of Diving Sites in Mabul Island, Malaysia

    Science.gov (United States)

    Zhang, Liye; Chung, ShanShan

    2015-12-01

    This study has explored social carrying capacity of an underwater environment based on divers' perceived crowding. Two dimensions were assessed, the number of divers seen and the proximity of diver. Data were obtained from a survey of 132 divers dived in Mabul Island, Malaysia during 2013-2014. Photographs depicting four levels of diver number and four levels of diver proximity in different combinations were shown to the respondents for assessing their acceptability. Between the two variables, the "number of divers" was the most influential factor for divers' perceived crowding. Divers would start to feel unacceptably crowded if 8-9 divers were visible to them at one time. Based on this, it is likely that the use level of diving sites in Mabul Island has already exceeded its social carrying capacity. Implications for future research and diving tourism management for Mabul Island are also discussed in the paper.

  8. Quantum Router for Single Photons Carrying Spin and Orbital Angular Momentum

    Science.gov (United States)

    Chen, Yuanyuan; Jiang, Dong; Xie, Ling; Chen, Lijun

    2016-01-01

    Quantum router is an essential element in the quantum network. Here, we present a fully quantum router based on interaction free measurement and quantum dots. The signal photonic qubit can be routed to different output ports according to one control electronic qubit. Besides, our scheme is an interferometric method capable of routing single photons carrying either spin angular momentum (SAM) or orbital angular momentum (OAM), or simultaneously carrying SAM and OAM. Then we describe a cascaded multi-level quantum router to construct a one-to-many quantum router. Subsequently we analyze the success probability by using a tunable controlled phase gate. The implementation issues are also discussed to show that this scheme is feasible. PMID:27256772

  9. Quantum Router for Single Photons Carrying Spin and Orbital Angular Momentum.

    Science.gov (United States)

    Chen, Yuanyuan; Jiang, Dong; Xie, Ling; Chen, Lijun

    2016-06-03

    Quantum router is an essential element in the quantum network. Here, we present a fully quantum router based on interaction free measurement and quantum dots. The signal photonic qubit can be routed to different output ports according to one control electronic qubit. Besides, our scheme is an interferometric method capable of routing single photons carrying either spin angular momentum (SAM) or orbital angular momentum (OAM), or simultaneously carrying SAM and OAM. Then we describe a cascaded multi-level quantum router to construct a one-to-many quantum router. Subsequently we analyze the success probability by using a tunable controlled phase gate. The implementation issues are also discussed to show that this scheme is feasible.

  10. Evaluation of Social Carrying Capacity of Topkapi Palace By Employees and Visitors

    Directory of Open Access Journals (Sweden)

    Kurban Ünlüönen

    2009-09-01

    Full Text Available Visitors’ using attraction resources at an optimum level is essential for the sustainable usage of areas. In fact Topkapı Palace arouses a considerable level of interest in terms of resources it has and this interest consequently leads to a concentration of visitors and a high degree of usage. The concentration in the area has utmost importance in terms of visitor carrying capacity. One of the groups who can evaluate the concentration present in this area most efficiently is the employees of the palace who are in continuous interaction with the visitors. One of the main objectives of this study is revealing the opinions of the employees on visitor carrying capacity. In order to gather information from the employees, face-to-face interview technique has been used and the evaluations of the employees have shown that visitor concentration has reached a level which may cause some negative results.

  11. Magnetic focusing of cold atomic beam with a 2D array of current-carrying wires

    Institute of Scientific and Technical Information of China (English)

    Yang Liu; Min Yun; Jianping Yin

    2006-01-01

    @@ A new scheme to realize a two-dimensional (2D) array of magnetic micro-lenses for a cold atomic beam,formed by an array of square current-carrying wires,is proposed.We calculate the spatial distributions of the magnetic fields from the array of current-carrying wires and the magnetic focusing potential for cold rubidium atoms,and study the dynamic focusing processes of cold atoms passing through the magnetic micro-lens array and its focusing properties by using Monte-Carlo simulations and trajectory tracing method.The result shows that the proposed micro-lens array can be used to focus effectively a cold atomic beam,even to load ultracold atoms or a BEC sample into a 2D optical lattice formed by blue detuned hollow beams.

  12. Biological Evaluation of ChuangYuLing Dressing-A Multifunctional Medicine Carrying Biomaterial

    Institute of Scientific and Technical Information of China (English)

    PENG Rui; ZHENG Qixin; HAO Jie; ZOU Yang; CHENG Jie

    2005-01-01

    The safety of Chuangyuling (CYL) dressing-a multifunctional medicine carrying biomaterial was evaluated in order to provide foundation for the application of CYL as material used in the wound healing. The traditional Chinese medicine (TCM) extract solution was compounded with scaffolds (gelatin and Bletilla hyacinthine gum), and then frozen and dried to form spongy and porous material CYL. According to the standard of biological evaluation of medical devices that was instituted by the ministry of health of China[1] , the biological evaluation of CYL dressing was conducted. The results showed that all the contents of biological evaluation test consisting of acute toxicity, skin irritation, sensitization and cytotoxicity met the requirement of standards. It was concluded that the biomaterial carrying TCM (CYL dressing) is safe for application of wound healing.

  13. Clinical features of Chinese patients with Huntington's disease carrying CAG repeats beyond 60 within HTT gene.

    Science.gov (United States)

    Liu, Z-J; Sun, Y-M; Ni, W; Dong, Y; Shi, S-S; Wu, Z-Y

    2014-02-01

    Patients with Huntington's disease (HD) carrying CAG repeats beyond 60 are less frequently seen and clinical features of them have been rarely reported. We identified four unrelated patients carrying CAG repeats beyond 60 (84.0 ± 13.76, ranging from 74 to 104) from 119 Chinese HD patients via direct sequencing. These four were all early onset with a mean age at presenting symptom of 9.8 ± 1.71 years. Paternal transmission was found in three of them and the fourth was apparently sporadic. In addition, they had atypical onset symptoms including epilepsy, intellectual decline, tics and walking instability, which might lead the clinicians to make the wrong diagnosis in the early stage of disease. Our work explores clinical features of Chinese HD patients with an expanded CAG repeat over 60 and may help the clinicians make a correct diagnosis in the early stage of disease.

  14. Superior Current Carrying Capacity of Boron Nitride Encapsulated Carbon Nanotubes with Zero-Dimensional Contacts.

    Science.gov (United States)

    Huang, Jhao-Wun; Pan, Cheng; Tran, Son; Cheng, Bin; Watanabe, Kenji; Taniguchi, Takashi; Lau, Chun Ning; Bockrath, Marc

    2015-10-14

    We report fabrication and characterization of hexagonal boron nitride (hBN)-encapsulated carbon nanotube (CNT) field effect transistors, which are coupled to electrical leads via zero-dimensional contacts. Device quality is attested by the ohmic contacts and observation of Coulomb blockade with a single periodicity in small bandgap semiconducing nanotubes. Surprisingly, hBN-encapsulated CNT devices demonstrate significantly enhanced current carrying capacity; a single-walled CNT can sustain >180 μA current or, equivalently, a current density of ∼2 × 10(10) A/cm(2), which is a factor of 6-7 higher than devices supported on SiO2 substrates. Such dramatic enhancement of current carrying capacity arises from the high thermal conductivity of hBN and lower hBN-CNT interfacial thermal resistance and has implications for carbon electronic applications.

  15. Enhanced load-carrying capacity of hairy surfaces floating on water.

    Science.gov (United States)

    Xue, Yahui; Yuan, Huijing; Su, Weidong; Shi, Yipeng; Duan, Huiling

    2014-05-08

    Water repellency of hairy surfaces depends on the geometric arrangement of these hairs and enables different applications in both nature and engineering. We investigate the mechanism and optimization of a hairy surface floating on water to obtain its maximum load-carrying capacity by the free energy and force analyses. It is demonstrated that there is an optimum cylinder spacing, as a result of the compromise between the vertical capillary force and the gravity, so that the hairy surface has both high load-carrying capacity and mechanical stability. Our analysis makes it clear that the setae on water striders' legs or some insects' wings are in such an optimized geometry. Moreover, it is shown that surface hydrophobicity can further increase the capacity of a hairy surface with thick cylinders, while the influence is negligible when the cylinders are thin.

  16. Assessing the Social Carrying Capacity of Diving Sites in Mabul Island, Malaysia.

    Science.gov (United States)

    Zhang, Liye; Chung, ShanShan

    2015-12-01

    This study has explored social carrying capacity of an underwater environment based on divers' perceived crowding. Two dimensions were assessed, the number of divers seen and the proximity of diver. Data were obtained from a survey of 132 divers dived in Mabul Island, Malaysia during 2013-2014. Photographs depicting four levels of diver number and four levels of diver proximity in different combinations were shown to the respondents for assessing their acceptability. Between the two variables, the "number of divers" was the most influential factor for divers' perceived crowding. Divers would start to feel unacceptably crowded if 8-9 divers were visible to them at one time. Based on this, it is likely that the use level of diving sites in Mabul Island has already exceeded its social carrying capacity. Implications for future research and diving tourism management for Mabul Island are also discussed in the paper.

  17. Land Potential Productivity and Population Carrying Capacity of Yan’an City

    Institute of Scientific and Technical Information of China (English)

    Xiaoling; LIU; Wei; ZHANG

    2013-01-01

    The productivity attenuation method is adopted to calculate land potential productivity of counties of Yan’an City and calculate population carrying capacity at current productivity level. Result shows that high photosynthetic potential productivity area and high light and temperature potential productivity area are mainly situated in the north,while high climatic potential area and high land potential productivity area are mainly concentrated in the south. From solar radiation,moisture and landform,the attenuation amplitude of land potential productivity in northern counties ( districts) is greater than that in southern counties ( districts) . In the whole city,the population carrying capacity of 9 counties reaches well-off living level,and 1 district still does not reach the level of adequate food and clothing. These results can provide reference for land resource use,agricultural production distribution and population growth control.

  18. Secure Naming and Addressing Operations for Store, Carry and Forward Networks

    Science.gov (United States)

    Eddy, Wesley M.; Ivancic, William D.; Iannicca, Dennis C.; Ishac, Joseph; Hylton, Alan G.

    2014-01-01

    This paper describes concepts for secure naming and addressing directed at Store, Carry and Forward (SCF) distributed applications, where disconnection and intermittent connectivity between forwarding systems is the norm. The paper provides a brief overview of store, carry and forward distributed applications followed by an in depth discussion of how to securely: create a namespace; allocate names within the namespace; query for names known within a local processing system or connected subnetwork; validate ownership of a given name; authenticate data from a given name; and, encrypt data to a given name. Critical issues such as revocation of names, mobility and the ability to use various namespaces to secure operations or for Quality-of-Service are also presented. Although the concepts presented for naming and addressing have been developed for SCF, they are directly applicable to fully connected systems.

  19. Analysis on economic carrying capacity index of pig breeding in China

    Science.gov (United States)

    Leng, Bi-Bin; Liu, Jia-Ling; Xu, Yue-Feng

    2017-08-01

    In this paper, factor analysis method was employed to analyze and calculate the Gross Domestic Product (GDP) per capita in the last decade, the proportion of research and experiment development (R&D) expenditure equivalent to GDP, urban and rural residents’ pork consumption and explored the scale of Chinese pig breeding on economic carrying capacity index. The result showed that the growth of GDP had led to better techniques and higher field investment, and stronger support like science and technology from the government provided good conditions for large scale of pig breeding. Besides, the substantial increase of pork consumption between rural and urban residents has contributed to the pig breeding in large scale. As a result, the economic carrying capacity index in Chinese pig farming is on the rise.

  20. Carrying pharyngeal of Streptococcus pyogenes and sensitivity profiles in schoolchild from Cartagena

    Directory of Open Access Journals (Sweden)

    Lucy Margarita Villafañe-Ferrer

    2015-07-01

    Full Text Available To determine the frequency of carrying pharyngeal of Streptococcus pyogenes and their sensitivity profiles in schoolchildren from Cartagena. Analytical cross-sectional study, the sample was composed by 131 children. Strains of Streptococcus pyogenes were identified using conventional methods. Antibiotic sensitivity was determined the Kirby-Bauer methods. A questionnaire was applied in order to identify risk factors associated.19,8% of children were carriers of bacterium. 26 isolates of Streptococcus pyogenes were obtained. To evaluate the sensitivity were found strains sensible to ceftriaxone and erytrhomycin (84,6% each one. 23,1% (6/26 0f isolates were resistant to ampicillin. It not was found association between carrying pharyngeal of Streptococcus pyogenes and risk factors (p>0,05. It were found resistant strains to antibiotics considered of first election for therapy of infectious diseases produced by this bacterium.

  1. Transfer of stem cells carrying engineered chromosomes with XY clone laser system.

    Science.gov (United States)

    Sinko, Ildiko; Katona, Robert L

    2011-01-01

    Current transgenic technologies for gene transfer into the germline of mammals cause a random integration of exogenous naked DNA into the host genome that can generate undesirable position effects as well as insertional mutations. The vectors used to generate transgenic animals are limited by the amount of foreign DNA they can carry. Mammalian artificial chromosomes have large DNA-carrying capacity and ability to replicate in parallel with, but without integration into, the host genome. Hence they are attractive vectors for transgenesis, cellular protein production, and gene therapy applications as well. ES cells mediated chromosome transfer by conventional blastocyst injection has a limitation in unpredictable germline transmission. The demonstrated protocol of laser-assisted microinjection of artificial chromosome containing ES cells into eight-cell mouse embryos protocol described here can solve the problem for faster production of germline transchromosomic mice.

  2. The effect of manufacturing tolerances on the load carrying capacity of large diameter bearings

    Indian Academy of Sciences (India)

    Starvin M S; Manisekar K

    2015-09-01

    This paper deals with simplified 3D finite element (FE) analysis on the effect of manufacturing tolerances on the load carrying capacity of large diameter bearings based on Hertz theory. The nonlinear connector elements are used to model the rolling elements. This model enables us to evaluate the contact load on the rolling elements with relatively reduced calculation time. FE study has been carried out by allocating tolerance on balls and raceways using Monte Carlo simulation technique. The variation in dimension on balls is taken as per IS 2898-1976. A coding has been developed and employed for Monte Carlo simulation. Using the results of Monte Carlo simulation, tolerance has been assigned to the elements of large diameter bearing. From the results of finite element analysis, it is identified that analysis of large diameter bearing with tolerance on ball and raceway will lead to safe design.

  3. The study of environmental carrying capacity for sustainable tourism in Telaga Warna Telaga Pengilon Nature Park, Dieng Plateu, Central Java

    Science.gov (United States)

    Melat Aryasa, Alexander; Nur Bambang, Azis; Muhammad, Fuad

    2017-06-01

    The increasing in quantity of the tourists visiting Telaga Warna Telaga Pengilon Nature Park, Dieng Plateau, Central Java, can cause a potential threat toward the conservation sustainability of the tourist attraction and the surrounding area. The utilization of conservation area for tourist attraction has to be carried out based on the principal of Environmental Carrying Capacity so that it will not affect the ecosystem. This study aims to determine the value of Telaga Warna Telaga Pengilon Nature Park environmental carrying capacity as a conservation area used for tourism activities. The environmental carrying capacities calculated in this study were physical carrying capacity, real carrying capacity, and effective carrying capacity. Results of this research show that the physical carrying capacity of The Telaga Warna Telaga Pengilon Nature Park was 31,302 visitors, the real capacity was 869 visitors/day and the effective carrying capacity was 579 visitors/day. Thus, the sustainable tourism development strategy is needed to manage the everlasting natural resources.

  4. Comment on "Invasive harlequin ladybird carries biological weapons against native competitors".

    Science.gov (United States)

    de Jong, Peter W; van Lenteren, Joop C; Raak-van den Berg, C Lidwien

    2013-09-20

    We comment on the implications that Vilcinskas et al. (Reports, 17 May 2013, p. 862) attach to the finding that the exotic, invasive ladybird Harmonia axyridis carries microsporidia to which this species is insensitive but that is lethal to species that are native to the invaded areas. The authors suggest that these microsporidia might serve as "biological weapons" against the native competitors, but we cast doubt on the importance of this suggestion in the field.

  5. Emergence of Citrobacter freundii carrying IMP-8 metallo-β-lactamase in Germany

    Science.gov (United States)

    Peter, S; Wolz, C; Kaase, M; Marschal, M; Schulte, B; Vogel, W; Autenrieth, I; Willmann, M

    2014-01-01

    Metallo-β-lactamases (MBLs) in Enterobacteriaceae are an increasing problem worldwide. This report describes the isolation of Citrobacter freundii carrying IMP-8 MBL from three patients during the period from March 2012 until March 2013 in Germany. The blaIMP-8 enzyme is predominantly found in Asia, where IMP-8 has spread to various enterobacterial species causing serious infections. To our best knowledge, this is the first report of blaIMP-8 habouring Enterobacteriaceae in Europe. PMID:25356340

  6. Emergence of Citrobacter freundii carrying IMP-8 metallo-β-lactamase in Germany

    Directory of Open Access Journals (Sweden)

    S. Peter

    2014-03-01

    Full Text Available Metallo-β-lactamases (MBLs in Enterobacteriaceae are an increasing problem worldwide. This report describes the isolation of Citrobacter freundii carrying IMP-8 MBL from three patients during the period from March 2012 until March 2013 in Germany. The blaIMP-8 enzyme is predominantly found in Asia, where IMP-8 has spread to various enterobacterial species causing serious infections. To our best knowledge, this is the first report of blaIMP-8 habouring Enterobacteriaceae in Europe.

  7. Scientific production on surgical nursing: analysis of the quantitative studies carried out between 2005 and 2009

    OpenAIRE

    2012-01-01

    This study aimed to analyze the characteristics of quantitative studies of nursing scientific publication in the surgical area. Research with quantitative approach carried out in the Virtual Healthcare Library with articles of quantitative nature, published from 2005 to 2009, in journals classified as A1, A2 and B1 by the Capes Nursing Qualis system 2008, full-text available on-line and in Portuguese. 28 articles were analyzed and it was detected that most of them are descriptive, exploratory...

  8. Integrating resource, social, and managerial indicators of quality into carrying capacity decision-making

    Science.gov (United States)

    Newman, P.; Marion, J.; Cahill, K.

    2001-01-01

    In park and wilderness management, integrating social and resource indicators is essential to meet park mandates that require the protection of both experiential and resource conditions. This paper will address the challenges we face in integrating social and resource data and outline a study in progress in Yosemite National Park. This study will develop and apply a management model that integrates resource, social and managerial indicators of quality into carrying capacity decisionmaking.

  9. Performance of women with fibromyalgia in walking up stairs while carrying a load

    OpenAIRE

    Daniel Collado-Mateo; Adsuar, José C; Pedro R. Olivares; Francisco J. Dominguez-Muñoz; Cristina Maestre-Cascales; Narcis Gusi

    2016-01-01

    Background. Fibromyalgia is a chronic disease characterized by widespread pain and other associated symptoms. It has a relevant impact on physical fitness and the ability to perform daily living tasks. The objective of the study was to analyze the step-by-step-performance and the trunk tilt of women with fibromyalgia in the 10-step stair climbing test compared with healthy controls. Methods. A cross-sectional study was carried out. Twelve women suffering from fibromyalgia and eight healthy co...

  10. Optimized design of BCD adder and Carry skip BCD adder using reversible logic gates

    OpenAIRE

    H.R.Bhagyalakshmi,; M K Venkatesha

    2011-01-01

    Reversible logic is very essential for the construction of low power, low loss computational structures which are very essential for the construction of arithmetic circuits used in quantum computation, nano technology and other low power digital circuits. In the present paper an optimized and low quantum cost one digit BCD adder and an optimized one digit carry skip BCD adder using new reversible logic gates are proposed. The proposed work is best compared to the other existing circuits.

  11. Weapon carrying, physical fighting and gang membership among youth in Washington state military families.

    Science.gov (United States)

    Reed, Sarah C; Bell, Janice F; Edwards, Todd C

    2014-10-01

    To examine associations between parental military service and school-based weapon carrying, school-based physical fighting and gang membership among youth. We used cross-sectional data from the 2008 Washington State Healthy Youth Survey collected in 8th, 10th, and 12th grades of public schools (n = 9,987). Parental military service was categorized as none (reference group), without combat zone deployment, or deployed to a combat zone. Multivariable logistic regression was used to test associations between parental military service and three outcomes: school-based weapon carrying, school-based physical fighting and gang membership. Standard errors were adjusted for the complex survey design. In 8th grade, parental deployment was associated with higher odds of reporting gang membership (OR = 1.8) among girls, and higher odds of physical fighting (OR = 1.6), and gang membership (OR = 1.9) among boys. In 10th/12th grade, parental deployment was associated with higher odds of reporting physical fighting (OR = 2.0) and gang membership (OR = 2.2) among girls, and physical fighting (OR = 2.0), carrying a weapon (OR = 2.3) among boys. Parental military deployment is associated with increased odds of reporting engagement in school-based physical fighting, school-based weapon carrying, and gang membership, particularly among older youth. Military, school, and public health professionals have a unique, collaborative opportunity to develop school- and community-based interventions to prevent violence-related behaviors among youth and, ultimately, improve the health and safety of youth in military families. Ideally, such programs would target families and youth before they enter eighth grade.

  12. Static Hedging with Uncertain Quantity and Departure from the Cost-of-Carry Valuation

    Institute of Scientific and Technical Information of China (English)

    Qing-wei Liu; Yi Li; Shou-yang Wang

    2006-01-01

    In this paper, we are concerned with the optimal hedge ratio under quantity risk as well as discrepancies between the futures market price and its theoretical valuation according to the cost-of-carry model.Assuming a geometric Brownian motion for forecasting process, we model mispricing as a specific noise component in the dynamics of futures market prices, based on which the optimal hedging strategy is calculated.Finally, we illustrate optimal strategy and its properties by numerical examples.

  13. Proof-Carrying Code Based Tool for Secure Information Flow of Assembly Programs

    Directory of Open Access Journals (Sweden)

    Abdulrahman Muthana

    2009-01-01

    Full Text Available Problem statement: How a host (the code consumer can determine with certainty that a downloaded program received from untrusted source (the code producer will maintain the confidentiality of the data it manipulates and it is safe to install and execute. Approach: The approach adopted for verifying that a downloaded program will not leak confidential data to unauthorized parties was based on the concept of Proof-Carrying Code (PCC. A mobile program (in its assembly form was analyzed for information flow security based on the concept of proof-carrying code. The security policy was centered on a type system for analyzing information flows within assembly programs based on the notion of noninterference. Results: A verification tool for verifying assembly programs for information flow security was built. The tool certifies SPARC assembly programs for secure information flow by statically analyzing the program based on the idea of Proof-Carrying Code (PCC. The tool operated directly on the machine-code requiring only the inputs and outputs of the code annotated with security levels. The tool provided a windows user interface enabling the users to control the verification process. The proofs that untrusted program did not leak sensitive information were generated and checked on the host machine and if they are valid, then the untrusted program can be installed and executed safely. Conclusion: By basing proof-carrying code infrastructure on information flow analysis type-system, a sufficient assurance of protecting confidential data manipulated by the mobile program can be obtained. This assurance was come due to the fact that type systems provide a sufficient guarantee of protecting confidentiality.

  14. Self-adjustment of Carrying Capacity of Concrete Embedded with CFRC

    Institute of Scientific and Technical Information of China (English)

    Wu YAO

    2006-01-01

    By heating up the embedded carbon fiber reinforced cement based material (CFRC), the carrying capacity and deformation of concrete member could be adjusted. The relationship between temperature difference and expansion strain of CFRC was demonstrated, and the temperature-deformation-load effect of concrete embedded with CFRC was studied. Heating the CFRC up to different temperatures resulted in different degree of inner pre-stress in concrete. Thus, the load capacity of concrete could be regulated owing to counteracting the pre-stress.

  15. Experimental Determination of Load Carrying Capacity of Point Contacts at Zero Entrainment Velocity

    Science.gov (United States)

    Shogrin, Bradley A.; Jones, William R., Jr.; Kingsbury, Edward P.; Prahl, Joseph M.

    1999-01-01

    A capacitance technique was used to monitor the film thickness separating two steel balls of a unique tribometer while subjecting the ball-ball contact to highly stressed, zero entrainment velocity (ZEV) conditions. All tests were performed under a N2 purge (R.H. carrying capacity at these zero entrainment velocity conditions, relevant to the ball-ball contact application in retainerless ball bearings.

  16. Thermal carrying capacity for a thermally-sensitive species at the warmest edge of its range.

    Directory of Open Access Journals (Sweden)

    Daniel Ayllón

    Full Text Available Anthropogenic environmental change is causing unprecedented rates of population extirpation and altering the setting of range limits for many species. Significant population declines may occur however before any reduction in range is observed. Determining and modelling the factors driving population size and trends is consequently critical to predict trajectories of change and future extinction risk. We tracked during 12 years 51 populations of a cold-water fish species (brown trout Salmo trutta living along a temperature gradient at the warmest thermal edge of its range. We developed a carrying capacity model in which maximum population size is limited by physical habitat conditions and regulated through territoriality. We first tested whether population numbers were driven by carrying capacity dynamics and then targeted on establishing (1 the temperature thresholds beyond which population numbers switch from being physical habitat- to temperature-limited; and (2 the rate at which carrying capacity declines with temperature within limiting thermal ranges. Carrying capacity along with emergent density-dependent responses explained up to 76% of spatio-temporal density variability of juveniles and adults but only 50% of young-of-the-year's. By contrast, young-of-the-year trout were highly sensitive to thermal conditions, their performance declining with temperature at a higher rate than older life stages, and disruptions being triggered at lower temperature thresholds. Results suggest that limiting temperature effects were progressively stronger with increasing anthropogenic disturbance. There was however a critical threshold, matching the incipient thermal limit for survival, beyond which realized density was always below potential numbers irrespective of disturbance intensity. We additionally found a lower threshold, matching the thermal limit for feeding, beyond which even unaltered populations declined. We predict that most of our study

  17. Thermal carrying capacity for a thermally-sensitive species at the warmest edge of its range.

    Science.gov (United States)

    Ayllón, Daniel; Nicola, Graciela G; Elvira, Benigno; Parra, Irene; Almodóvar, Ana

    2013-01-01

    Anthropogenic environmental change is causing unprecedented rates of population extirpation and altering the setting of range limits for many species. Significant population declines may occur however before any reduction in range is observed. Determining and modelling the factors driving population size and trends is consequently critical to predict trajectories of change and future extinction risk. We tracked during 12 years 51 populations of a cold-water fish species (brown trout Salmo trutta) living along a temperature gradient at the warmest thermal edge of its range. We developed a carrying capacity model in which maximum population size is limited by physical habitat conditions and regulated through territoriality. We first tested whether population numbers were driven by carrying capacity dynamics and then targeted on establishing (1) the temperature thresholds beyond which population numbers switch from being physical habitat- to temperature-limited; and (2) the rate at which carrying capacity declines with temperature within limiting thermal ranges. Carrying capacity along with emergent density-dependent responses explained up to 76% of spatio-temporal density variability of juveniles and adults but only 50% of young-of-the-year's. By contrast, young-of-the-year trout were highly sensitive to thermal conditions, their performance declining with temperature at a higher rate than older life stages, and disruptions being triggered at lower temperature thresholds. Results suggest that limiting temperature effects were progressively stronger with increasing anthropogenic disturbance. There was however a critical threshold, matching the incipient thermal limit for survival, beyond which realized density was always below potential numbers irrespective of disturbance intensity. We additionally found a lower threshold, matching the thermal limit for feeding, beyond which even unaltered populations declined. We predict that most of our study populations may become

  18. Determination of foraging thresholds and effects of application on energetic carrying capacity for waterfowl.

    Science.gov (United States)

    Hagy, Heath M; Kaminski, Richard M

    2015-01-01

    Energetic carrying capacity of habitats for wildlife is a fundamental concept used to better understand population ecology and prioritize conservation efforts. However, carrying capacity can be difficult to estimate accurately and simplified models often depend on many assumptions and few estimated parameters. We demonstrate the complex nature of parameterizing energetic carrying capacity models and use an experimental approach to describe a necessary parameter, a foraging threshold (i.e., density of food at which animals no longer can efficiently forage and acquire energy), for a guild of migratory birds. We created foraging patches with different fixed prey densities and monitored the numerical and behavioral responses of waterfowl (Anatidae) and depletion of foods during winter. Dabbling ducks (Anatini) fed extensively in plots and all initial densities of supplemented seed were rapidly reduced to 10 kg/ha and other natural seeds and tubers combined to 170 kg/ha, despite different starting densities. However, ducks did not abandon or stop foraging in wetlands when seed reduction ceased approximately two weeks into the winter-long experiment nor did they consistently distribute according to ideal-free predictions during this period. Dabbling duck use of experimental plots was not related to initial seed density, and residual seed and tuber densities varied among plant taxa and wetlands but not plots. Herein, we reached several conclusions: 1) foraging effort and numerical responses of dabbling ducks in winter were likely influenced by factors other than total food densities (e.g., predation risk, opportunity costs, forager condition), 2) foraging thresholds may vary among foraging locations, and 3) the numerical response of dabbling ducks may be an inconsistent predictor of habitat quality relative to seed and tuber density. We describe implications on habitat conservation objectives of using different foraging thresholds in energetic carrying capacity models and

  19. Physiological Strain During Load Carrying: Effects of Mass and Type of Backpack

    Science.gov (United States)

    2001-05-01

    and Type of Backpack DISTRIBUTION: Approved for public release, distribution unlimited This paper is part of the following report: TITLE: Soldier...UNCLASSIFIED 1-1 Physiological Strain During Load Carrying: Effects of Mass and Type of Backpack Michael Holewijn and Ted Meeuwsen Netherlands Aeromedical...were quantified. While standing, oxygen uptake was not influenced by the type or mass of the backpack , and averaged 10% maximal oxygen uptake. The heart

  20. BIOSPEX: Biological space experiments, a compendium of life sciences experiments carried on US spacecraft

    Science.gov (United States)

    Anderson, M.; Rummel, J. A. (Editor); Deutsch, S. (Editor)

    1979-01-01

    United States space life science experiments, encompassing 27 years of experience beginning with sounding rocket flights carrying primates (1948) to the last U.S. spaceflight, the joint US/USSR Apollo Test Project (1975), are presented. The information for each experiment includes Principal Investigators, the program and mission on which it was flown, the specimens used, the objectives, protocol, equipment, results, conclusions, and bibliographic reference citations for publications derived from each experiment.