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Sample records for hertzberger giuseppe serazzi

  1. HOMAGE A HERTZBERGER

    DEFF Research Database (Denmark)

    2016-01-01

    to few Hertzberger was also strongly inspired by the juxtaposition of objects as seen in the works of the Italian painter Giorgio Morandi. Specifically He was in search of the space in-between in Morandis works (fig. V) To make a long story short Hertzberger never won the competition, but still today...... the entry remains as an important example of urban planning approached in a structuralist way. Ever since the project has come to my attention the distinctive geometric expression deriving from simple cuts of a “standard block” has been of great inspiration. Likewise the strong spatial identity...

  2. Un ricordo di Giuseppe Pontiggia

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    Nanni Cagnone

    2014-07-01

    Full Text Available Segue la testimonianza su Giuseppe Pontiggia nel partecipato ricordo del poeta e narratore Nanni Cagnone. Sfiorando letteratura, filosofia, storia, filologia attraverso il richiamo alle conversazioni tra i due amici, si restituiscono i contorni culturali e soprattutto umani dello scrittore.

  3. Selected works of Giuseppe Peano

    CERN Document Server

    Kennedy, Hubert, C

    1973-01-01

    In the decade before 1900, the Italian mathematician Giuseppe Peano was one of the most original and influential pioneers of modern mathematical logic. He made significant contributions to the development of the foundations of mathematics and the axiomatic method, dimension theory, measure theory, and vector analysis, among other areas.

  4. Giuseppe Sergi, "champion" of Darwinism?

    Science.gov (United States)

    Volpone, Alessandro

    2011-01-01

    The Italian anthropologist, psychologist and evolutionist Giuseppe Sergi (1841-1936) may be regarded in some respects today as an "atypical" Darwinist, but, almost paradoxically, he was considered a "champion" of Darwinism by colleagues and commentators of his own time. Probably, two aspects of his work are responsible for this apparent anomaly: his faith in the so-called soft inheritance and his claims regarding a theory concerning the polyphyletic origin of human races. The soft inheritance theory, however, was needed by Sergi to support ideas regarding the complexity of inheritance in man, a fact that, in his opinion, could not completely be put down to mechanical laws, and polygeny was useful when trying to rectify the problem concerning the incompleteness of the fossil record. In both cases, it is possible to show that he was involved in supporting Darwinian theory during the most severe crisis of its consensus in Italy and at International level, between the end of the 19th century and the beginning of the 20th. Finally, the apparent unorthodox features which can be found in Sergi's ideas appear to be, in Kuhnian terms, ad hoc hypotheses put forward by Sergi himself in order to support the paradigm.

  5. Giuseppe Cafiero sulle orme di Joyce a Roma

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    Carla De Petris

    2011-08-01

    Full Text Available In 2006 Giuseppe Cafiero published James Joyce, Roma & altre storie, a novel with thriller-like undertones that weaves stories around the author of Ulysses. In her conversation with the author, Carla de Petris investigates the genesis of the novel and reflects on the post-modernist stances of its complex plot.

  6. Maria and Giuseppe: lives intertwined with CERN’s history

    CERN Multimedia

    Pauline Gagnon

    2014-01-01

    CERN will be celebrating its 60th anniversary this year. That means 60 years of pioneering scientific research and exciting discoveries. Two Italian physicists, Maria and Giuseppe Fidecaro, remember nearly all of it since they arrived in 1956. Most impressively, they are still hard at work, every day!   Giuseppe and Maria Fidecaro in Restaurant No. 1, at CERN, in 2014, 60 years after they joined the Organization. The couple is easy to spot, even in the cafeteria during busy lunchtimes, where they usually engage in the liveliest discussions. “We argue quite a lot,” Maria tells me with a big smile. “We have very different styles.” “But in general, in the end, we agree,” completes Giuseppe. In October 1954, Giuseppe went to the University of Liverpool as a CERN Fellow to do research at its brand new synchrocyclotron. Maria also joined, having obtained a fellowship from the International Federation of University Women. After getting m...

  7. Giuseppe Moscati (1880-1927): a holistic approach to medicine.

    Science.gov (United States)

    Ponti, Giovanni; Tomasi, Aldo

    2014-05-01

    Giuseppe Moscati was a physician, medical school professor and a pioneer in the field of biochemistry and Italian studies on diabetes. He was declared a Catholic saint in 1987. In order to respond better to both the physical and spiritual needs of his patients, he developed his own holistic approach to healthcare involving meticulous drug regimens, meditation and discipline. © The Author(s) 2013 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

  8. Giuseppe Pasta (1742-1823): protophysician and pioneer of psychological studies in the medical field.

    Science.gov (United States)

    Clerici, Carlo Alfredo; Veneroni, Laura; Poli, Marco

    2009-11-01

    Giuseppe Pasta was a pioneer of psychological support in physical disease. Born in Bergamo, Italy, he was a cousin of the physician Andrea Pasta who was a pupil of Giovanni Battista Morgagni. Giuseppe's cultural and clinical resources were the teachings of Francesco Redi's medical school in Tuscany. This paper discusses the courage and philosophical tolerance of disease and the etiquette of the physician.

  9. Giuseppe Antonino Biondo e la fondazione dell’International Recording

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    Paolo Biondo

    2015-08-01

    Full Text Available Giuseppe Antonino Biondo (1899-1988, a US citizen of Italian origins, was one of the most important entrepreneurs in the fields of discography and film sound post-production in Italy. A leading figure at American RCA, G.A. Biondo moved to Rome during the 1950s, where he founded RCA Italiana and, a few years later, International Recording, which became one of the main post-production companies in Italy until the 2000s. These operations deeply impacted on the technological and industrial setting of Italian cinema. In this essay we recall G.A. Biondo’s early years in the US and we deal with the chain of events that led to the birth of International Recording.

  10. The Great Bravery of Croatian Soldier by Giuseppe Maria Mitelli

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    Daniel Premerl

    2018-04-01

    Full Text Available The article approaches the iconography of two etchings with Croatian subject matter made by the Bolognese etcher Giuseppe Maria Mitelli in 1684. In the focus is the etching Great Bravery of Croatian soldier (Gran prodezza di soldato croatto. The author concludes, interpreting the explanatory text below the etching, that it depicts an event of the so-called Great Turkish War (1683-1699. The depicted hero belonged to the Croatian Regiment commanded by general James Leslie, and the depicted heroic act occurred, in all probability, during the battle of Virovitica in 1684. Also, the author points out to a model for Mitelli's etching as well as to the literary image of the simultaneous decapitation of both a horseman and a horse in the Croatian literature. In the same year, Mitelli also made the portrait of the Zagreb bishop and the politician Martin Borković. The existence of both etchings is associated with the Illyrian-Hungarian College in Bologna, governed by the Zagreb cathedral Chapter. L'articolo indaga l'iconografia di due incisioni con soggetto croato realizzate dall'incisore bolognese Giuseppe Maria Mitelli nel 1684. Il focus del saggio è l'incisione Gran prodezza di soldato croatto. Interpretando il testo esplicativo sotto l'acquaforte, l'autore ritiene che essa raffiguri un evento della cosiddetta Grande Guerra Turca (1683-1699. L'eroe raffigurato apparteneva al reggimento croato comandato dal generale James Leslie e l'atto eroico raffigurato avvenne, con ogni probabilità, durante la battaglia di Virovitica nel 1684. L'autore individua inoltre un modello per l'incisione di Mitelli e un riferimento a una fonte nella letteratura croata ove compare la decapitazione simultanea di un cavaliere e di un cavallo. Nello stesso anno Mitelli fece anche il ritratto del vescovo di Zagabria e del politico Martin Borković. L'esistenza di entrambe le acqueforti è associata al Collegio illirico-ungarico di Bologna, governato dal Capitolo della

  11. Tre voci per un Lexicon di Giuseppe Pontiggia

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    Daniela Marcheschi

    2014-07-01

    Full Text Available Tre parole-chiave offrono lo spunto per un’immersione nel pensiero e nell’opera di Giuseppe Pontiggia. La prima: parola, riaffermata dallo scrittore in quanto atto civile e ‘corporeo’ mediante il quale l’uomo fa esperienza di se stesso entrando in contatto con i suoi simili e con il circostante, ricongiungendosi insieme alla sua più profonda e antica natura. Viene così restituita allo scrittore/critico la responsabilità di lottare contro l’attuale minaccia dello svuotamento linguistico, nel nome di una costruttiva utopia culturale. La seconda parola, musica, serve a illuminare i romanzi di Pontiggia – in specie La grande sera e L’arte della fuga – attraverso suggestive analogie con la musica classica e il jazz, predilette dallo scrittore. Ossimoro è l’ultima voce di questo Lexicon: figura retorica, ma soprattutto figura conoscitiva che permette allo scrittore di scoprire la propria verità e il proprio linguaggio e al lettore di abbracciare una visione non lineare e problematica del mondo, capace di ampliare le prospettive e rinnovare lo sguardo.

  12. Giuseppe Sergi. The portrait of a positivist scientist.

    Science.gov (United States)

    Cerro, Giovanni

    2017-12-30

    Giuseppe Sergi (1841-1936) was one of the most important anthropologists and psychologists of the age of positivism and this article focuses on three domains of his scientific research: degeneration, eugenics and race. His concept of degeneration is defined as the development of special forms of human adaptation to the environment. This issue is closely related to his theory of the "stratification of character", which had a profound impact on Italian psychiatry and criminal anthropology in the late nineteenth century. Thus, special emphasis is placed on the differences between Sergi and Cesare Lombroso regarding their definitions of criminality and genius. Concerning eugenics, the article analyzes Sergi's key role in the Italian context, discussing his eugenic program based on both repression and education. His remedies against the spread of degeneration included not only radical and repressive measures, but also the improvement of popular education and the living conditions of the working class. In the field of physical anthropology, the article examines Sergi's morphological method of classifying ethnic groups. Although sharply criticized in Italy and abroad, this method had two major effects. First, it led to the definitive split between Sergi and Paolo Mantegazza and to the foundation of the Societá Romana di Antropologia in 1893. Second, it was the starting point for Sergi's theory of Mediterranean "stock", which claimed that European populations were of African origin in contrast to contemporary theories of Aryan supremacy. The article ends with a look at the heated debate over Sergi's Mediterraneanism during the period of Fascism.

  13. Giuseppe Gradenigo: Much more than a syndrome! Historical vignette.

    Science.gov (United States)

    Matis, Georgios K; de A Silva, Danilo O; Chrysou, Olga I; Karanikas, Michail A; Birbilis, Theodossios A

    2012-01-01

    Giuseppe Gradenigo (1859-1926), a legendary figure of Otology, was born in Venice, Italy. He soon became a pupil to Adam Politzer and Samuel Leopold Schenk in Vienna, demonstrating genuine interest in the embryology, morphology, physiopathology, as well as the clinical manifestations of ear diseases. In this paper, the authors attempt to highlight the major landmarks during Gradenigo's career and outline his contributions to neurosciences, which have been viewed as looking forward to the 20(th) century rather than awkward missteps at the end of the 19(th). Several rare photographs along with many non-English, more than a century old articles have been meticulously selected to enrich this historical journey in time. It was after Gradenigo that the well-known syndrome consisting of diplopia and facial pain due to a middle ear infection was named. However, Gradenigo was much more than a syndrome. Surprisingly, despite the fact that he is considered a pioneer of the Italian Otology of the late 19(th) and early 20(th) century, little is written of his life and his notable achievements in the English literature. Even though his name lives on nowadays only in the eponym "Gradenigo's syndrome," his accomplishments are much wider and cast him among the emblematic figures of science. His inherent tendency for discovering the underlying mechanisms of diseases and his vision of guaranteeing quality of services, professional proficiency, respect, and dedication toward the patients is in fact what constitutes his true legacy to the next generations.

  14. DEL AULA A LA CIUDAD. ARQUETIPOS URBANOS EN LAS ESCUELAS PRIMARIAS DE HERMAN HERTZBERGER / FROM THE CLASSROOM TO THE CITY. URBAN ARCHETYPES IN HERMAN HERTZBERGER´S PRIMARY SCHOOLS

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    Esther Mayoral-Campa

    2017-11-01

    Full Text Available RESUMEN Herman Hertzberger pertenece a ese grupo de arquitectos que, desde comienzos del siglo XX hasta nuestros días, han entendido el binomio arquitectura–pedagogía como indisoluble, como dos disciplinas complementarias en el proceso de aprendizaje que recrean un modelo de sociedad y, por ende, del espacio donde esta se desarrolla. Hertzberger entiende la arquitectura como instrumento pedagógico y como oportunidad esencial para la configuración de un espacio de relación. Su obra nos desvela una preocupación máxima por el usuario, por los valores colectivos, en un entendimiento de la arquitectura como soporte de libertad, cuyo antecedente inmediato fue el ideario de su maestro Aldo van Eyck. Pero es en su arquitectura escolar donde esto se observa de forma más radical. A través de los numerosos proyectos realizados vinculados a la educación, se recorren todas las etapas de aprendizaje del hombre desde la infancia hasta la universidad, en los cuales se desarrolla un amplio repertorio de estrategias proyectuales vinculadas a la Escuela Activa como modelo de aprendizaje y más concretamente al Método Montessori. Su dilatada obra vinculada a la enseñanza le permite ensayar en todos los registros posibles la idea de un edificio como ciudad, difuminando los límites entre espacios privados y públicos en todas las escalas entre la escuela y su entorno, en un recorrido que va del aula a la ciudad. SUMMARY Herman Hertzberger belongs to a group of architects that understand the architecture-pedagogy binomial as indissoluble. Ever since the beginning of the 20th Century, they have embraced the complementarity of these two disciplines in the educational world, and have revealed the way architecture and pedagogy collaborate through the recreation of a model for society and therefore influence the place where education takes place. In this context, Hertzberger understands architecture as a pedagogical tool as well as an opportunity for the

  15. [Giuseppe Saverio Poli: magnetic therapy in Palermo at the beginning of XIX cent].

    Science.gov (United States)

    Mazzola, Roberto

    2011-01-01

    The article presents a not well known text written by Giuseppe Saverio Poli, one of the most important South italian scientist, living and working between the end of XVIII century and the first years of XIX century. The Breve saggio sulle virtù curative della calamita, printed in Palermo in 1811, is a short text devoted to one of the most controversial scientific topic of those years, magnetic therapy.

  16. Giuseppe and Aloysius Frari's works on rabies and history of Frari medical family of Sibenik, Dalmatia.

    Science.gov (United States)

    Krnić, Anton

    2007-06-01

    This article is an attempt to reconstruct the family history of the Fraris, the famous Sibenik medical family. Three generations of physicians from the Frari family played an important role not only at medical and social scene of Sibenik in the 18th and 19th century, but also in Croatian and Italian medical history. I will try to provide important details on the lives, medical and social work, and publications of 5 members of the family, Giuseppe (Josip), Angelo Antonio (Andeo Antun), Sebastiano (Sebastijan), Michele Carlo (Mihovil), and Aloysius (Luigi) Frari. I would also like to pay a special attention to the works on rabies, written by Giuseppe and Luigi Frari, which are among the earliest and most accurate Croatian works on the subject. To reconstruct the history of the family, I studied the relevant editions about the medical and social history of Sibenik, Dalmatia, Venice, and Croatia, together with the Fraris' publications and reflections. This was the first time Italian and Latin language works by Giuseppe and Luigi Frari on rabies were analyzed. The story on Fraris also documents that medical publishing was a common practice in Dalmatia in the 18th and the 19th century.

  17. PROF. GIUSEPPE MOSCATI (1880-1927). A SPECIAL ISSUE ON HIS SCIENTIFIC PRODUCTION

    OpenAIRE

    Cascella, Marco

    2016-01-01

    Professor Giuseppe Moscati (1880-1927) was canonized by the Catholic Church in 1987. This act recognized the extraordinary qualities of a doctor who, considering his work as a “sublime mission”, dedicated his life to helping the sick. The fame of the “Holy doctor” or “doctor of the poor”, as people called him, was soon widespread and, immediately after his death, made him the subject of several biographies. These treatises, mainly written by religious hagiographers, have little analyzed Mosca...

  18. La forza in comune dei videogiochi. Giuseppe Frazzetto, Molte vite in multiversi. Nuovi media e arte quotidiana, Mimesis Edizioni, 2011

    Directory of Open Access Journals (Sweden)

    Federico Giordano

    2012-03-01

    Full Text Available Giuseppe Frazzetto insegna storia dell’arte contemporanea e discipline afferenti le nuove forme mediali presso l’Accademia di Belle Arti di Catania ed è fra i pochi in Italia ad accostare organicamente all’approccio umanistico nei confronti delle arti contemporanee, quello al videogioco. Questi interessi si esercitano chiaramente nel suo testo Molte vite in multiversi.

  19. Histochemistry for the research in veterinary science: the legacy of Giuseppe Aureli

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    A Lauria

    2009-06-01

    Full Text Available Twenty years ago, on April 24th 1984, Giuseppe Aureli, Founding Member and President of the Italian Society of Histochemistry from 1971 to 1973, Director of the Institute of Anatomy of Domestic Animals, Histology and Embryology and Dean of the School of Veterinary Medicine of the University of Milan, died suddenly and before his time. Following in the footsteps of Carlo Bignardi, he started from the time he was a student, to deal with the research approaches of Maffo Vialli, founder of histochemistry in Italy Head in Milan of a skilled group of scientists, he developed a sound and reliable research school mainly based on the use of ever more advanced histochemical and cytochemical techniques to study, in the extensive area of veterinary science, different problems aimed at developing either basic knowledge or animal production.

  20. [An illustrious unknown. Giuseppe Levi among science, anti-fascism and Nobel Prizes].

    Science.gov (United States)

    Grignolio, Andrea; De Sio, Fabio

    2009-01-01

    The anatomist Giuseppe Levi (1872-1965) is unanimously considered one of the major figures of Italian biomedical sciences in the 20th century. His fame, however, is mainly derived from having nurtured three Nobel Prize winners, namely Salvador E. Luria, Rita Levi Montalcini and Renato Dulbecco. In reappraising Levi's role in the development of Italian science and culture in general, this article aims at questioning both the narrowness of earlier accounts and a certain kind of genealogical approach to the history of scientific disciplines and academic schools. We will here consider Giuseppe Levi as an instance of two major cultural phenomena: the development of experimental biology in Italy and continental Europe and the anti-fascist socialist culture expressed by a part of the Italian intellectuals. In so doing, we will reassess the historical specificity of the scientific maturation of Levi's three famous students, on the one hand, while on the other we will consider in some depth the cultural and moral environment in which Levi thrived and his role as a moral example for his students. Such revision, we will argue, have a direct bearing on more general historiographical issues, namely, the need for a stronger contextualization of the birth and consolidation of research traditions, implying a rejection of simplistic genealogical reconstructions, and the role of academic schools and institutional settings in the definition of novel, multidisciplinary scientific approaches. Finally, the following will highlight the importance of a more careful outlook on the master-pupil relationship in academic context, addressing issues of both continuity and rupture. The article is subdivided in two main sections, the first devoted to Levi as a scientist, the second to his Anti-fascism.

  1. Identity, memory and la diarchia di bronzo Commemorating Vittorio Emanuele II and Giuseppe Garibaldi in post-Risorgimento Venice

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    Laura Parker

    2011-12-01

    Full Text Available Identità, memoria e la diarchia di bronzo Una commemorazione di Vittorio Emanuele II e Giuseppe Garibaldi nella Venezia postrisorgimentale   Questo saggio tratta della collocazione di due monumenti nella città di Venezia, nella seconda metà dell’Ottocento. Dopo l’unificazione della penisola, il nuovo governo ha capito chiaramente la necessità di costruire un’identità nazionale nella quale si potessero riconoscere le cento città. L’erezione di monumenti e l’organizzazione di varie commemorazioni – che hanno celebrato i protagonisti e gli eventi più importanti del Risorgimento – sono stati usati per ‘fare gli italiani’ nell’ambito postrisorgimentale. In questo contesto, l’articolo esplora la commemorazione di Vittorio Emanuele II e Giuseppe Garibaldi nella città lagunare, e analizza se la fusione tra mito risorgimentale e storia locale sia effettivamente realizzata.

  2. Donatello Strangio & Giuseppe Sancetta (Eds.), Italy in a European Context: Research in Business, Economics, and the Environment

    OpenAIRE

    CUCARI, Nicola

    2016-01-01

    Abstract. Contributing to support the diffusion of an European culture and sense of citizenship. This is the aim of the book “Italy in a European Context: Research in Business, Economics, and the Environment” edited by Donatella Strangio & Giuseppe Sancetta.  It is a collection of scholarly articles that cover the main issues related to role of Italy offering different perspectives ranging from economics and management, among others. It is a good read not only for students and scholars wi...

  3. “Imperfetto perfettismo”: le riforme costituzionali nell’Italia del secondo dopoguerra. Intervista a Giuseppe Carlo Marino

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    Giuseppe Carlo Marino

    2016-09-01

    Full Text Available In the interview sent to Diacronie. Studi di Storia contemporanea on 18th August 2016, the historian Giuseppe Carlo Marino recalls the basic aspects of the italian political contemporary history by focusing on the institutional dynamics that have to do with the changes of the power structure from the liberal up to the republican period, by contextualizing the latest changes of the italian constitution within the most general global, social, economic and political dynamics.

  4. Commentary: Giuseppe Campani (1635-1715, Rome, Italy): the First Use of a Microscope in Medicine and Surgery.

    Science.gov (United States)

    Brogna, Christian; Millesi, Matthias; Fiengo, Leslie; Richardson, Mark; Bhangoo, Ranjeev; Ashkan, Keyoumars; Türe, Ugur

    2018-02-01

    Giuseppe Campani (1635-1715) was a polymath in Rome, Italy, during the Scientific Revolution in the XVIIth century. In particular, he forged the screw barrel microscope and was manufacturing his own lenses for microscopes and telescopes. He mastered the art of lens grinding. Those lenses have been analyzed with modern methods and turned out to be of extremely good quality, shining light on the fact that Giuseppe Campani mastered the theories of optics. Moreover, in a letter that Giuseppe Campani sent to Pope Innocent XI, he clearly described the use of a microscope for the examination of wounds of legs. This letter dates back to 15 August 1686 and is the first evidence of the use of microscopes to analyze wounds, sores, and anatomic specimens in medical and surgical settings. MG Yasargil previously showed the lithography accompanying this letter and was the first to recognize its great importance. We accessed this original letter in the Vatican Library, and for the first time we have translated it from Latin to English in order to unveil its significance in the context of the Scientific Revolution and the history of medicine and surgery. Copyright © 2017 by the Congress of Neurological Surgeons.

  5. Giuseppe and Aloysius Frari’s Works on Rabies and History of Frari Medical Family of Šibenik, Dalmatia

    Science.gov (United States)

    Krnić, Anton

    2007-01-01

    This article is an attempt to reconstruct the family history of the Fraris, the famous Šibenik medical family. Three generations of physicians from the Frari family played an important role not only at medical and social scene of Šibenik in the 18th and 19th century, but also in Croatian and Italian medical history. I will try to provide important details on the lives, medical and social work, and publications of 5 members of the family, Giuseppe (Josip), Angelo Antonio (Anđeo Antun), Sebastiano (Sebastijan), Michele Carlo (Mihovil), and Aloysius (Luigi) Frari. I would also like to pay a special attention to the works on rabies, written by Giuseppe and Luigi Frari, which are among the earliest and most accurate Croatian works on the subject. To reconstruct the history of the family, I studied the relevant editions about the medical and social history of Šibenik, Dalmatia, Venice, and Croatia, together with the Fraris’ publications and reflections. This was the first time Italian and Latin language works by Giuseppe and Luigi Frari on rabies were analyzed. The story on Fraris also documents that medical publishing was a common practice in Dalmatia in the 18th and the 19th century. PMID:17589982

  6. Macbeth by Giuseppe Verdi and the Romantic reception of William Shakespeare’s drama

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    Alina Borkowska-Rychlewska

    2010-01-01

    Full Text Available Romantic approach to William Shakespeare’s dramatic works, as well as the notions and questions so vital for the consciousness of the epoch concerning the capacity and function of destiny, unrecognizability of existence, interference of supernatural powers in the world that can be grasped with human mind and common sense, are all intriguingly transparent in Giuseppe Verdi’s Macbeth. The Italian composer, who knew the Romantic reception of Shakespeare’s dramatic plays well (e.g. the Italian translations of the lectures given by August W. Schlegel, embarked upon the issue of the ambiguity of the scene with the witches that appear to Macbeth, posed a question on the cognitive value in the dreamy apparition (in the brilliantly constructed Lady Macbeth’s sleepwalking scene, and, finally, emphasized the aspect of hybridity of the world that inseparably combines the grandeur and the grotesque (the point highlighted in Victor Hugo’s considerations on Shakespeare. The two versions of the operatic Macbeth — the one produced in Florence in 1847, the other, 1865 revised version produced for Paris — relate well with the long sequence of changeable conventions in the nineteenth century theatre, taking into consideration its requirements (the need for a spectacular character of staging, the introduction of multiple Ake a Romantic implant in the operetta world of farcical braggadocio dominant on the Parisian stage at the time of the Second Empire, testifies to the enormous influence of the Romantic reception of Shakespeare exerted at the time and defining for a considerable period of time the concept of adaptation of the works of the Stradford master to meet the needs of the operatic stage.

  7. [Prof. Giuseppe Moscati (1880-1927). A special issue on his scientific production].

    Science.gov (United States)

    Cascella, Marco

    2016-08-01

    Professor Giuseppe Moscati (1880-1927) was canonized by the Catholic Church in 1987. This act recognized the extraordinary qualities of a doctor who, considering his work as a "sublime mission", dedicated his life to helping the sick. The fame of the "Holy doctor" or "doctor of the poor", as people called him, was soon widespread and, immediately after his death, made him the subject of several biographies. These treatises, mainly written by religious hagiographers, have little analyzed Moscati as a doctor and scientist, or, in rare cases, privileged the description of his medical career, touching only marginally salient aspects of his work as a scientist and researcher. The purpose of this paper is to provide an insight into the figure of Moscati as a scientist, contextualizing his research activities in the scientific fields of biochemistry and physiology, which were flourishing in the early twentieth century. By a more careful analysis, his scientific production appears original for the resource-poor context and the innovative research method. The Italian scientist, combining physiological chemistry and biochemistry at the clinic, anticipated the birth of modern branches as the "Laboratory Medicine" and the "Clinical Pathology". In particular, he carried out studies on diabetes, storage diseases, metabolism, toxicology, pathology, nephrology and occupational diseases. Moreover, he anticipated the concept of modern laboratory in the oncological field as means for the characterization of the "nature" of neoplasms and related therapeutic approaches. Therefore, even if Moscati was rarely mentioned by the sources of the history of medicine, it is safe to assume that the fame of the Saint has paradoxically eclipsed that of the scientist, preventing him from receiving the necessary reward.

  8. Voortgezet diagnostisch onderzoek naar een betere beheersing van een aantasting door de schimmel Colletotrichum acutatum bij de bollenteelt van tulpen cv. Giuseppe Verdi

    NARCIS (Netherlands)

    Vink, P.

    2008-01-01

    Sinds 1992 kennen we een ziekte bij de teelt van tulpen in metname de cultivar Giuseppe Verdi (en de laatste tijd ook wel eens in andere tulpencultivars) waarbij de bollen worden aangetast door de schimmel Colletotrichum acutatum. Daardoor gaan de bollen na de oogst verloren of groeien er in een

  9. Un omaggio a Giuseppe Bellini attraverso un libro a lui dedicato: cuando quiero hallar las voces, encuentro con los afectos...

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    Emilia Perassi

    2015-01-01

    Full Text Available Il presente articolo si propone di tracciare il ritratto di uno dei grandi maestri di studi ispanoamericanistici, Giuseppe Bellini, attraverso una recente opera miscellanea a lui dedicata, a cura di Patrizia Spinato Bruschi e Jaime Martínez. Tale raccolta di saggi non solo restituisce le linee, i contenuti e le forme di una produzione critica monumentale ma ben mostra l’importante ruolo di studioso e di uomo che il Bellini è stato capace di esercitare, articolando attorno a sé una nutrita scuola, a partire dalla visione della letteratura come rete di dialogo e di scambio. I diversi temi affrontati dai più di cinquantacinque saggi mostrano la straordinaria capacità del Bellini di tessere una proficua rete di relazioni, di studio e di amicizia, e di promuovere l’ispanoamericanismo italiano, sempre attraverso il riconoscimento della letteratura come lezione civile e del buon vivere.

  10. Giuseppe E. Sansone traduttore di lirica romanza medievale. Contributo per una storia della traduzione poetica in Italia

    Directory of Open Access Journals (Sweden)

    Speranza Cerullo

    2013-07-01

    Full Text Available La traduzione di poesia medievale in Italia ha avuto notevole sviluppo negli ultimi venti anni, attraverso l’incremento dell’attività dei traduttori e la promozione di un confronto su questioni di ordine teorico o metodologico, strettamente legate al tema dell’attualizzazione del testo medievale. In questo quadro, il contributo di Giuseppe Sansone ha svolto un ruolo di primo rilievo, attraverso un’attività ininterrotta che conta la pubblicazione di scritti di indirizzo critico-teorico e di cinque antologie di lirica medievale di diversi ambiti linguistici – occitano, spagnolo, catalano, galego e, in misura minore, francese –, offrendo modelli e appunti di metodo nei quali competenze scientifiche e filologiche si coniugano con una sensibilità estetica d’autore, guidata dall’obiettivo primario di una rifondazione del testo poetico nella sua letterarietà, dove la traduzione in versi si propone come testo dotato di una propria autonomia estetica.Over the last twenty years the translation of medieval poetry in Italy has had considerable development due to the increased activity of the translators; besides, a debate on theoretical or methodological issues closely related to the theme of updating medieval texts has been promoted. In this context, the contribution of Giuseppe Sansone and his continuous activity has played a key role: he published critical-theoretical essays and five anthologies of medieval lyrics from different linguistic areas – Provençal, Spanish, Catalan, Galician and, to a lesser extent, French – thus offering models and methodological suggestions in which scientific and philological skills combine with aesthetic sensibility, driven from the primary method of re-founding the poetic text in its literary property, in which the verse translation is proposed as a text with its own aesthetic autonomy.

  11. Unknown Angels by Giuseppe Groppelli in Zadar and the Former Altar of St Anastasia in the Cathedral

    Directory of Open Access Journals (Sweden)

    Damir Tulić

    2016-01-01

    Full Text Available As the former capital of Dalmatia, Zadar abounded in monuments produced during the 17th and 18th century, especially altars, statues, and paintings. Most of this cultural heritage had been lost by the late 18th and the first decades of the 19th century, when the former Venetian Dalmatia was taken over by Austrian administration, followed by the French and then again by the Austrian one. Many churches were closed down, their furnishings were sold away or lost, and the buildings were either repurposed or demolished. One of them had been home to two hitherto unpublished angels-putti located on the top of the inner side of the arch in the sanctuary of Zadar’s church of Our Lady of Health (Kaštel at the end of Kalelarga (Fig. 1. Both marble statues were obviously adjusted and then placed next to the marble cartouche with a subsequently added inscription from 1938, which tells of a reconstruction of the church during the time it was administered by the Capuchins. The drapery of the right angel-putto bears the initials I. G., which should be interpreted as the signature of the Venetian sculptor Giuseppe Groppelli (Venice, 1675-1735. This master signed his full name as IOSEPH GROPPELLI on the base of a statue of St Chrysogonus, now preserved in the Permanent Exhibition of Religious Art in Zadar (Fig. 2. Same as the signed statue of St Anastasia by master Antonio Corradini (Fig. 3, it used to form part of the main altar in Zadar’s monumental church of St Donatus, desacralized in 1798. Recently, two more angels have been discovered, inserted in the tympanum of the main altar in the church of Madonna of Loreto in Zadar’s district of Arbanasi, the one to the right likewise bearing the initials I. G. (Fig. 4. Undoubtedly, these two artworks were once part of a single composition: the abovementioned former altar in the church of St Donatus, transferred to the cathedral in 1822 and reconstructed to become the new altar in the chapel of St Anastasia

  12. The correspondence of Giovanni Santini and Giuseppe Lorenzoni, directors of the Astronomical Observatory of Padua in the 19th century

    Directory of Open Access Journals (Sweden)

    Luisa Pigatto

    2009-06-01

    Full Text Available

    Giovanni Santini was appointed director of the Astronomical Observatory of Padova from 1817 to 1877. His scientific correspondence covers a period from 1807 to 1874. Most of the letters are from Italian and European astronomers, mainly concerning astronomical subjects. In actual fact, all Santini’s activity was devoted to the classical astronomy, mainly to the new comets and planets orbit calculation, as far as to the compilation of a catalogue of almost ten thousand stars. From 1821 to 1828, he was involved in geodetic observations in order to determine the difference of longitude between Milan-Padua and Padua-Fiume. Giuseppe Lorenzoni was appointed director after Santini’s death, from 1877 to 1913. Since 1873, he took part in the Italian Geodetic Commission to which he devoted almost all his scientific activity. Lorenzoni’s scientific correspondence was partly lost for war reasons. A partial correspondence with Giovanni Virginio Schiaparelli and almost the complete correspondence with Pietro Tacchini, were recovered after the second World War. Santini and Lorenzoni correspondence cover a period about a hundred years long. So, it is an important tool of knowledge for the history of Padova Astronomical Observatory in the 19th century, for its scientific activity, and for the relationship among Italian and European astronomers and institutions.



  13. There is something inauthentic in each original: a very brief study of the illusion from the movie “The Best Offer”of Giuseppe Tornatore

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    Rogério de Almeida

    2016-06-01

    Full Text Available Based on the film The Best Offer (LA MIGLIORE OFFERTA, 2013, by Giuseppe Tornatore, this article proposes a reflection on the illusion of the double expressed by the original-copy dichotomy. After a brief introduction of how this dichotomy has become paradigmatic in the western thought, we point out the philosophy of Clément Rosset to discuss the central theme of the film: “there is always something authentic in each copy”. We argue, finally, that the illusion is not only to transform something into two, but also in the deluded's unwillingness to approve a reality that is impossible to duplicate.

  14. Hints of popular voice. Through (and in spite of Giuseppe Gioachino Belli and Agustín García Calvo

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    Gerardo Gimona

    2018-01-01

    Full Text Available ¿Así que es para esto para lo que servía la literatura? ¿Para negar, uno tras otro, artículos de fe y dejarnos sin creencia ni idea alguna? ¿Servía, cuando era buena y cuando en algún caso acertaba, para negarse también a sí misma? ¿Y es que debía ante todo negarse a sí misma para poder decir algo que nos sonara a verdad? Pues algo de esto parece ocurrir en los sonetos que Giuseppe Gioachino Belli escribió, como si en ellos hablara directamente el pueblo y no un literato ni un autor culto, en dialecto romanesco; y es esto, precisamente, lo que intentaremos ir ahora comprobando, atendiendo al libro Giuseppe Gioachino Belli. 47 sonetos romanescos con las versiones de Agustín García Calvo (Editorial Lucina, Zamora, 2006.

  15. Giuseppe Stellardi, Gadda

    African Journals Online (AJOL)

    User

    Torino: Einaudi, 1999: 116-19; come anche, prima di lui, Sanguineti,. Barilli, Cases, Fortini, Baldacci e, forse, De Benedetti, come attesterebbero, e silentio, le rare e scarne menzioni di Gadda, prettamente di raffronto, nel pur voluminoso Il romanzo del. Novecento, Milano: Garzanti, 19984: vd.: 11, 18, 161, 315, 399); se la.

  16. Giuseppe Viesti - An appreciation

    Science.gov (United States)

    Natowitz, Joseph B.

    2016-07-01

    Professor Giussepe Viesti of the Department of Physics of the University of Padova, an outstanding researcher in both fundamental and applied nuclear science and a dedicated supporter of Latin American Nuclear Science died in January 2015. The following brief appreciation was presented in a memorial session celebrating and honoring his professional life, his accomplishments and his enduring impact on his science and on his colleagues.

  17. Giuseppe Castiglione (Lang Shining, precursor de la primera mundialización pictórico-arquitectónica

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    Manuel V. Castilla

    2016-09-01

    Full Text Available La obra del hermano lego jesuita Giuseppe Castiglione (nombre chino, Lang Shining, 1688-1766, desarrollada en la China Qing, no fue suficientemente conocida sino hasta el siglo xx, y se ha investigado muy poco sobre su papel precursor de la primera mundialización artística. Su aproximación a China fue primordialmente de carácter apostólico, como consecuencia de la acción misional. Esta misión estuvo basada en un proceso inculturador fundamentado, a su vez, en el intercambio de las ciencias y las artes. Este artículo pone de manifiesto el riguroso conocimiento que sobre perspectiva matemática lineal había adquirido Castiglione en Europa, y la trascendencia que tuvo en la hibridación cultural y artística en la China del siglo xviii. Su posible repercusión en manifestaciones artísticas posteriores en otros territorios constituye el tema central del trabajo. Desde el punto de vista artístico, dada su privilegiada posición en la corte imperial, el artista jesuita jugó un papel decisivo en los nuevos métodos pictórico-arquitectónicos que se desarrollaron en la dinastía Qing. Sus murales, retratos, caballos, flores y pájaros, fueron elogiados y admirados por el emperador Qianlong, y mucho tiempo después por diseñadores y pintores europeos. Al simbolismo y la sensibilidad de la pintura asiática, Castiglione añadió el misterio del ilusionismo mágico que encierra la perspectiva matemática lineal europea, que contenía la llave y el secreto del conocimiento geométrico de Lang Shining. Sin embargo, sus efectos no fueron exclusivamente artísticos, sino que en muchos casos tuvieron una vigorosa dimensión apostólica. La dimensión religiosa que presuponemos en las pinturas de los artistas jesuitas fue una herramienta esencial en el proceso de inculturación; en este sentido, G. Castiglione usó la perspectiva no sólo como una técnica que gustaba a los emperadores, y fundamentalmente al emperador Qianlong, sino también como

  18. Sub anno domini 1465... In casa de’ figliuoli di Aldo. Origin and advancements of the printing press in Italy through the exemplars of the Bagnacavallo ‘Giuseppe Taroni’ library

    OpenAIRE

    Federica Fabbri

    2016-01-01

    The paper contains the descriptions of the ancient books owned by the Public Library ‘Giuseppe Taroni’ in Bagnacavallo, which were selected for the exhibition Sub anno domini 1465... In casa de’ figliuoli di Aldo to celebrate the printing of the first book in Italy by Konrad Sweynheym and Arnold Pannartz with datation included in the colophon (Subiaco, 1465) and the fifth centenary of Aldus Manutius’ death, the major Italian printer and publisher of the Renaissance age (1449-52?-1515). Among ...

  19. Entre el Ejército del Comintern y la solidaridad antifascista: la trayectoria de Giuseppe Di Vittorio en el debate sobre la naturaleza de las Brigadas Internacionales

    Directory of Open Access Journals (Sweden)

    Josep PUIGSECH FARRÀS

    2011-05-01

    Full Text Available El debate historiográfico sobre la naturaleza de las Brigadas Internacionales durante la Guerra Civil Española de 1936-1939 se encuentra hoy día fracturado entre las tesis favorables a su sumisa supeditación a los intereses del partido-Estado Soviético y aquellas que apuestan por otorgarle un cierto grado de autonomía y una importante dosis de solidaridad. Sin embargo, este debate dispone de una nueva fuente de análisis gracias a la trayectoria de uno de los máximos dirigentes del citado cuerpo internacionalista, Giuseppe Di Vittorio. El histórico militante antifascista italiano generó una amplia y controvertida actividad durante los meses que estuvo presente en la República Española, entre octubre de 1936 y febrero de 1937. Así, ocupó el tercer lugar en el escalafón directivo de la sede española de las Brigadas Internacionales en Albacete, participó activamente en la defensa de Madrid, desarrolló una intensa capacidad propagandística para difundir las Brigadas Internacionales entre la población civil republicana, protagonizó diferentes conflictos políticos y personales con otros miembros del aparato brigadista y fue retirado del territorio republicano en extrañas circunstancias. Así, pues, su amplia y variada actividad al frente de las Brigadas Internacionales le convierte en un protagonista privilegiado para analizar la naturaleza de las Brigadas Internacionales.

  20. Rendiconti finanziari e struttura di governo del Seminario di Siena in S. Giorgio durante la reggenza dell’Arcivescovo Giuseppe Mancini (1824-1855 = Financial reports and governance structure of s. Giorgio Seminary in Siena, during the Archbishop Giuseppe Mancini regency (1824-1855

    Directory of Open Access Journals (Sweden)

    Giussepe Caturi

    2016-06-01

    Full Text Available Este artículo tiene como objetivo investigar una particular dimensión cultural de una comunidad social: la religiosa. Su premisa básica es la idea que hay muchas correlaciones e interdependencias entre los diferentes aspectos de la cultura de un pueblo, por lo que los cambios en uno de ellos pueden causar cambios en todos los demás. Entonces, no se puede pensar la cultura religiosa de una comunidad como distante desde la económica y científica, porque cada uno de ellas tiene el ser humano como elemento central y original. Por otra parte, la dimensión religiosa es tan penetrante en el alma humana, que se puede considerar como algo que caracteriza una comunidad. En esta perspectiva, es muy importante la misión sacerdotal que requiere una formación específica que se puede adquirir a través de cursos de estudio impartidos en los “seminarios”. Estas entidades eclesiásticas constituyen nuestro objeto de estudio, con especial referencia a lo que, hasta hoy, ha operado en la Diócesis de Siena. La comunidad social de Siena es extraordinariamente atractiva por su historia política y administrativa, por su patrimonio artístico y cultural y, sobre todo, por el sentimiento religioso de su población, lo que ha generado muchos grandes santos como Catalina Benincasa y Bernardino. El estudio, con un enfoque económico-empresarial, se refiere al sistema de contabilidad y a la estructura de gobierno de la institución analizada. Considerado su historia turbulenta y llena de eventos, limitamos la investigación a un período significativamente interesante: la regencia diocesana del Arzobispo Giuseppe Mancini (1824-1855, cuando se estaban absorbiendo las supresiones leopoldinas y napoleónicas y el Seminario estaba en la Iglesia de San Jorge. Lo studio intende indagare su di una particolare dimensione culturale delle comunità sociali: quella religiosa. La sua premessa di base è la consapevolezza delle numerose correlazioni e interdipendenze

  1. Apuntes para un estudio de la escultura genovesa en España. Comentarios en torno a Giuseppe Gaggini y el tabernáculo marmóreo de La Orotava, Tenerife (1822-1823

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    Juan Alejandro Lorenzo Lima

    2010-03-01

    Full Text Available Canarias fue desde el siglo XVI un enclave receptivo a la importación de mármoles y esculturas de todo tipo contratadas en Génova, por lo que conviene replantear el análisis de ese fenómeno partiendo de precedentes historiográficos y documentación inédita de archivo. En este artículo estudio de un modo detallado el tabernáculo que el escultor Giuseppe Gaggini labró para la parroquia de matriz de La Orotava antes de 1823, aportando testimonios inéditos que insisten en su valía creativa, religiosa y mercantil al ser «producto» de una época concreta.

  2. Sub anno domini 1465... In casa de’ figliuoli di Aldo. Origin and advancements of the printing press in Italy through the exemplars of the Bagnacavallo ‘Giuseppe Taroni’ library

    Directory of Open Access Journals (Sweden)

    Federica Fabbri

    2016-11-01

    Full Text Available The paper contains the descriptions of the ancient books owned by the Public Library ‘Giuseppe Taroni’ in Bagnacavallo, which were selected for the exhibition Sub anno domini 1465... In casa de’ figliuoli di Aldo to celebrate the printing of the first book in Italy by Konrad Sweynheym and Arnold Pannartz with datation included in the colophon (Subiaco, 1465 and the fifth centenary of Aldus Manutius’ death, the major Italian printer and publisher of the Renaissance age (1449-52?-1515. Among the exhibited copies the one belonging to the Roman edition of 1470 of the work of the Christian scholar Lactantius, the only one copy printed by Sweynheym and Pannartz owned by the Library in Bagnacavallo, and a selection of books printed by Aldus Manutius and his heirs, among which the only copy found in this library of a book printed by Aldus The Elder, belonging to Institutiones Grammaticae of 1514.

  3. Ka Aafrikas tehakse filme / Giuseppe Gariazzo

    Index Scriptorium Estoniae

    Gariazzo, Giuseppe

    2004-01-01

    Tallinna VIII Pimedate Ööde Filmifestivalil on fookuses postkoloniaalse Aafrika filmikunst. Artikkel käsitleb Mali ja Senegali, Burkina Faso ning Põhja-Aafrika (Maroko, Al̓eeria, Tuneesia ja Egiptus) filmindust

  4. ANTROPOLOGIA DI UN INTELLETTUALE, GIUSEPPE CASSIERI

    African Journals Online (AJOL)

    Di conseguenza la mancata possibilità di esprimersi, di esistere, di vivere si ripercuote nell'assenza di sogni, a discapito di una attività e creatività mentale che viene inibita nei livelli più profondi. “Il trio canonico di memoria, tradizione ed identità”. (106) viene ad essere messo in discussione dallo stesso Cassieri perché.

  5. The First Published History of Universal Architectural Models. Jean-Nicholas-Louis Durand’s Recueil et parallèle des édifices de tout genre, anciens et modernes (Paris 1800, and the Extended Italian Edition of Giuseppe Antonelli (Venice 1833

    Directory of Open Access Journals (Sweden)

    Vincenzo Fontana

    2014-06-01

    Full Text Available “Recueil et parallèle des édifices de tout genre, anciens et modernes”, published in Paris in 1799-1800 by Jean- Nicholas-Louis Durand, at the height of the positivistic climate engendered by the contemporary culture of encyclopedism, plays an important role in architectural historiography. The volume allowed architectural students and architectural enthusiasts alike the first opportunity to study a vast range of architectural design models of all periods and places organised into typological categories, illustrated in highly didactic and homogenous drawings. The immediate success of the “Recueil” was guaranteed by the simultaneous publication (in 1800 of an explanatory text to accompany the illustrative material, written by Jacques Guillaume Legrand in accordance with Durand. More than thirty years later, the Venetian editor Giuseppe Antonelli proposed a re-launch of the “Recueil” intended to meet the contemporaneous historical and critical context of modern Europe, publishing a bilingual Italian-French edition of highly commercially ambitious scope. The Venetian “Raccolta”, which appeared in 1833, united Legrand’s text with Durand’s illustrations, - and importantly included almost double the illustrations- with the addition of antique buildings, and also included modern architectural models, alongside contemporary Italian, French and German architectural design projects. This contribution intends to set Antonelli’s ambitious undertaking into the contemporaneous critical and vivacious academic cultural climate of the Venice of the 1830’s, and also includes a thorough examination of the additional illustrations that were added by the Venetian publisher to the original French canon.

  6. Kes kardab poeete? / Giuseppe Provenzano ; tõlk. Katrin Tombak

    Index Scriptorium Estoniae

    Provenzano, Giuseppe

    2008-01-01

    Tallinna Harjumäele rajatavast Vabaduse monumendist, ummiku äärele jõudnud avalikust diskussioonist, monumendi tähendusest. Õnnestunud monument peab esmajoones puudutama meie hinge ja tal ei tohiks puududa ilu

  7. Giuseppe Bonaviri, Silvinia, Milano: Mondadori, 1997. Muovendo da ...

    African Journals Online (AJOL)

    User

    natura, tradizione, mito, sogno, magia, ignoto, memoria, mistero, scienza, fantascienza, filosofia, tempo, storia s'intrecciano ricreando il misterioso, pulsante delirio dell'universo. Temi tutti percorsi da quell'acceso lirismo che anima l'intera produzione poetica dello scrittore, ora raccolta ne Il dire celeste (1993). È un lucido ...

  8. Giuseppe Zago, Sguardi storici sull’educazione dell’infanzia. Studi in onore di Mirella Chiaranda

    OpenAIRE

    Ostenc, Michel

    2017-01-01

    Mirella Chiaranda a enseigné pendant de longues années à l’université de Padoue. Ses travaux de recherche sont en grande partie consacrés à la réflexion pédagogique, mais ils vouent une attention particulière à la méthodologie de l’histoire de l’éducation. La pédagogue manifeste alors tout son intérêt pour des études profondément immergées dans les réalités politiques, économiques, sociales et religieuses de l’époque qui permettent d’appréhender les aspects les plus concrets de la vie quotidi...

  9. Giuseppe Bragalli and Bolognese ceiling painting in the Czech Lands in the 17th century

    Czech Academy of Sciences Publication Activity Database

    Mádl, Martin

    2011-01-01

    Roč. 59, č. 5 (2011), s. 350-379 ISSN 0049-5123 R&D Projects: GA ČR GA408/08/0745 Institutional research plan: CEZ:AV0Z80330511 Keywords : baroque art * painting * ceiling painting * architecture Subject RIV: AL - Art, Architecture, Cultural Heritage

  10. Il silenzio delle api. L’universo femminile di Giuseppe Dessì

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    Piero Mura

    2015-07-01

    Full Text Available Women’s time in Dessi’s works is always a long wait, which since pregnancy - that kind of motherhood  either actual or  potential, often peculiar to his female characters -  covers the whole span of their lives. A wait made of stone like Sardinia/ the Island. Similarly, men’s job is the return from all the fights of life, either real or metaphorical, attempted or accomplished, useless or worthwhile. The return to the woman,  to the mother and consequently to Sardinia which is both the womb and the tomb of their lives. In Dessì’s narrative, such waits are told through silence rather than by words. From Mariangela Eca’s stubborn and awkward silence in the novel “The Deserter” which is a prayer and a speechless attitidu (“epicedium”, to the contrast between the aphasic understanding of the young girl, main character in the short story “La mano della bambina” (she utters only one word throughout the whole story and her mother’s verbose dullness, (she seems to suggest that words are not necessary to understand  but empathy can be enough and finally, to the servant girl’s social background in the story “La serva degli asini”, who begins to live again as a person only when the silence of her family’s women sets her free. That is a mightier weapon than the sword or the tongue

  11. Giuseppe Samonà historian of architecture: his relationship with Gustavo Giovannoni

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    Fabrizio Di Marco

    2014-12-01

    Full Text Available The essay is intended to highlight the links between Samonà and the "Roman School", in part already analyzed in previous studies. In particular, we contextualize the six letters addressed to Gustavo Giovannoni between late 1929 and mid-1930, preserved in the Giovannoni Archive (Rome, Centro di Studi per la Storia dell’Architettura and listed in full in the appendix. The letters are mainly related to the studies of Samonà on late Renaissance architecture in Sicily, conducted in 1927 at the suggestion of Ernesto Calandra, which would then be gathered into four essays published between 1932 and 1935, profoundly influenced by the historical-critical ‘giovannoniano’ method. The epistolary contacts with Giovannoni, as well as promoting cultural growth and the rise of the career of teaching, not well structured at the time, show his attempt to get closer to Rome. This is evidenced by repeated references in the letters to Alberto Calza Bini, who was to assist him in obtaining a position at the University of Naples and who, together with Giovannoni and Piacentini, ruled in favor of Samonà in design competitions in the thirties, especially for the Post Office building in the Appio neighborhood in Rome.

  12. Dalle Americhe all’Europa: la sfortunata trasmigrazione degli erbari di Carlo Luigi Giuseppe Bertero (1789-1831

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    Claudia Borri

    2013-11-01

    Full Text Available Carlo Bertero was trained in Alba and then in Turin, studying with very good teachers who taught him, in addition to botany, political and ethical principles. After having studied the domestic flora, the young botanist travelled to the Antilles (1816-1821, to Chile (1827-1830 and to Tahiti (1830-1831. Thanks to his scientific works many new species were recognized and many specimina were sent to Europe to collectors as well as to botanic gardens, being spread out in different places. When, in 1831, the boat, on which Bertero was boarded, sank into Pacific ocean, all his collection of Tahitian plants disappeared with him. Despite of the dispersion of the collected materials, the botanists have been successful in reconstructing a good part of his activity. Nevertheless his unique writing appeared on the magazine El Mercurio Chileno, when the botanist was living in Santiago during the government of F.A. Pinto, the first liberal president of such country. The historical documentation has disclosed that, during his co-operation with the magazine, the Italian botanist supported the governmental policy, being consistent with his juvenile principles. When Pinto was overthrown, after a fierce civil war, which brought the conservative party to the power, Bertero fell into disgrace and had to leave the country, while the mission to write a natural story of Chile was granted to his competitor, the French botanist Claude Gay, who joined the new political course.

  13. The unfinished mechanics of Giuseppe Moletti an edition and English translation of his dialogue on mechanics, 1576

    CERN Document Server

    Laird, Walter, R

    2000-01-01

    Laird sets Moletti's Dialogue within the historical background of medieval and Renaissance mechanics, sketches the life and works of Moletti, and analyses the arguments and the geometrical theorems of the Dialogue.

  14. Deformation and fracture mechanics of engineering materials

    National Research Council Canada - National Science Library

    Hertzberg, Richard W; Vinci, Richard Paul; Hertzberg, Jason L

    2012-01-01

    "Hertzberg's 5th edition of Deformation & Fracture Mechanics of Engineering Materials offers several new features including a greater number and variety of homework problems using more computational software...

  15. Recommendations

    DEFF Research Database (Denmark)

    Baumeister, Ruth

    2016-01-01

    This article discusses three book publications: C. Kerez: Uncertain Certainty, Tokyo, 2013 H. Hertzberger: Lessons for students in architecture, Rotterdam, 2006, (1991) A. Jorn: Om Formen, Silkeborg, 2014, (1958)......This article discusses three book publications: C. Kerez: Uncertain Certainty, Tokyo, 2013 H. Hertzberger: Lessons for students in architecture, Rotterdam, 2006, (1991) A. Jorn: Om Formen, Silkeborg, 2014, (1958)...

  16. Giuseppe Patota, Grammatica di riferimento della lingua italiana per stranieri, Società Dante Alighieri; Firenze, Le Monnier, 2003; 424 pp.

    Directory of Open Access Journals (Sweden)

    Pavao Tekavčić

    2004-12-01

    Full Text Available Fra le tante grammatiche della lingua italiana pubblicate finora quella che qui recensiamo occupa un posto particolare grazie a certe qualità che mettteremo in rilievo, naturalmente in modo succinto, date le dimensioni della recensione.L'autore, professore all'Atteneo di Siena, ha pubblicato ultimamente alcuni titoli di carattere divulgativo (si veda la copertina anteriore interna e l'opera presente continua quest'attività, tanto utile quanto importante per quanti si dedicano all'i­taliano.

  17. Not a geography of what doesn't exist, but a counter-geography of what does: Rereading Giuseppe Dematteis' Le Matafore della Terra

    NARCIS (Netherlands)

    Fall, J.J.; Minca, C.

    2013-01-01

    The shaping of geography as a discipline has been the result of a combination of productive and successful communication and missed opportunities, of presence and absence, of fluid travels of ideas and projects, but also of closures, impediments, good lessons that got lost. This paper suggests that

  18. Giuseppe and Maria Fidecaro inside the spark chamber apparatus in the South Hall of PS to search for the $\\rho \\rightarrow \\pi\\gamma$ decay

    CERN Multimedia

    Gérard Bertin; CERN PhotoLab

    1964-01-01

    The lens, the so-called front view (see album https://cds.cern.ch/record/1974123), was used in the S30 experiment to converge onto a camera parallel light rays from the front of a large spark chamber. A second identical lens, the so-called top view, and a large mirror were used to take pictures at 90 degrees in such a way to determine the x,y coordinates in the horizontal plane of each spark. Details of the optics are reported in the note: A $\\gamma$-ray detector for the study of the electromagnetic decay of resonances, INFN/AE - 67/7, 20 Jun 1967, by F. Bradamante, G. Fidecaro, M. Fidecaro, M. Giorgi, F. Sauli, P. Schiavon.

  19. Nabothian cyst

    Science.gov (United States)

    ... Procedures for Primary Care . 3rd ed. Philadelphia, PA: Elsevier Mosby; 2011:chap 135. Dolan MS, Hill C, ... FA, eds. Comprehensive Gynecology . 7th ed. Philadelphia, PA: Elsevier; 2017:chap 18. Hertzberg BS, Middleton WD. Pelvis ...

  20. DARPA Quantum Network Testbed

    Science.gov (United States)

    2007-07-01

    Antonio Bovino, Pietro Varisco, Anna Maria Colla, Giuseppe Castagnoli, Giovanni Di Giuseppe and Alexander V. Sergienko “Effective Fiber-Coupling of...Giovanni Di Giuseppe Brian Imhausen Harvard University Teammate John Myers Tai Wu Leo Donnelly NIST Teammate Sae Woo Nam Bob Schwall Robert...A. M. Colla, G. Castagnoli, G. Di Giuseppe, and A. V. Sergienko, “Practical Quantum Key Distribution Using Polarization Entangled States

  1. Tüdimus ; Levant ; Agoonia ; Varjutus ; Mälestuseks ; Jõed ; Jõulud ; Kui sina mu vend ; Faas ; Maetud sadam ; Õhtul ; Needus ; Juuni ; Magada ; Rahu : [luuletused] / Giuseppe Ungaretti ; tõlk. Malle Talvet ja Auli Ott

    Index Scriptorium Estoniae

    Ungaretti, Giuseppe

    2003-01-01

    Andmed autori kohta lk. 28. Orig.: Noia ; Levante ; Agonia ; Chiaroscuro ; In memoria ; I fiumi ; Natale ; Se tu mio fratello ; Fase ; Il porto sepolto ; Stasera ; Dannazione ; Giugno ; Dormire ; Quiete

  2. Pædagogisk teori & arkitektonisk form

    DEFF Research Database (Denmark)

    Berg Nielsen, Kristian

    2000-01-01

    "Om Hertzbergers skoler kan det sammenfattende siges, at de både er i overensstemmelse med dette overordnede formål og med de intentioner, som ligger i Montessori-tænkningen. I forhold til dette pædagogiske program er arkitektens rolle den samme som ved andre typer af byggerier: making space...

  3. HTS Teologiese Studies / Theological Studies - Vol 12, No 2 (1956)

    African Journals Online (AJOL)

    H . W . Hertzberg , Die Bücher Josua, Richter, Ruth übe rs etzt und erk lárt . Das Alte Testament Deutsch, Teilband 9. Göttingen, Vandenhoeck u. Ruprecht. 1953. S.281 · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. B Gemser, 80-81 ...

  4. Ülestähendusi Birgitta festivalilt 2009 / Raili Sule

    Index Scriptorium Estoniae

    Sule, Raili, 1944-

    2009-01-01

    13.-23. augustini Pirita kloostri varemetes toimunud Tallinna Filharmoonia korraldatud Birgitta festivali raames toimunud Dmitri Bertmanni lavastustest - Umberto Giordano "Siber" ja Giuseppe Verdi "Falstaff"

  5. Imagined China. Italian Ideas and Visions of the “Celestial Empire ...

    African Journals Online (AJOL)

    ... della semplicità e autenticità della cultura cinese (Verri, Foscolo, Leopardi); dai primi tentativi di indagine comparata (Giuseppe La Farina) alla percezione, nelle pionieristiche analisi di Carlo Cattaneo e di Giuseppe Ferrari, di una Cina quale paese moderno, potenzialmente concorrenziale nei confronti dell'occidente.

  6. Taking a Regional Healthcare Coalition Approach to Mitigating Surge Capacity Needs of Mass Casualty or Pandemic Events

    Science.gov (United States)

    2012-06-01

    gaining motivation for employees or, as exemplified in this case, coalition participants.59 The theory posits that there are two factors that... Motivation -Hygiene/Satisfiers Two-Factor Theory outline from the 1959 book; The Motivation to Work by Frederick Hertzberg; NetMBA web search 2/24/12; http...www.netmba.com/mgmt/ob/ motivation / herzberg / 43 of the work of the group, individual responsibility given to members, achievements of the

  7. Nursing in Turkey.

    Science.gov (United States)

    Baumann, Steven L

    2006-10-01

    The current discussion on the nursing shortage needs to focus as much on nursing job satisfaction and retention as on nursing recruitment and education. Selected aspects of the motivational psychology of Abraham Maslow, Mihaly Csikszentmihalyi, and Frederick Hertzberg are here discussed in light of the challenges-opportunities of nursing in Turkey and elsewhere. Also discussed is an innovative program to support the application of nursing theory and professional development in Toronto, Canada.

  8. Quality of Working Life - An Exploration of Contributing Factors and their Relative Salience to Employees

    OpenAIRE

    Blackford, Katherine

    2015-01-01

    The academic study of Quality of Working Life (QoWL) has a long tradition, vestiges of which are apparent in the classic job satisfaction and employee motivation research (see for example, Mayo and Warner, 1931; Maslow, 1943; 1932; Blauner 1964; Hertzberg, 1966). The intervening years have witnessed the accumulation of a broad, complex and, at times contradictory, literature relating to variables identified as impacting on QoWL. The potential value of investing in enhancing QoWL cannot be und...

  9. "Mees, naine ja köök" ootab järge / Reet Varblane

    Index Scriptorium Estoniae

    Varblane, Reet, 1952-

    2007-01-01

    Eneken Maripuu ja Hannes Starkopfi näitus "Mees, naine ja köök" Hobusepea galeriis kuni 6. VIII. Hannes Starkopf on lähtunud itaalia maneristliku maalikunstniku Giuseppe Archimboldo (1527-1593) teosest "Suvi"

  10. Vtoraja zhizn klassiki estonskogo kinematografa / Tiit Tuumalu

    Index Scriptorium Estoniae

    Tuumalu, Tiit, 1971-

    2006-01-01

    Oskar Lutsu jutustuse järgi valminud mängufilm "Kevade" restaureeriti ja digitaliseeriti Soomes Digital Film Finland poolt, restauraator Giuseppe di Giorgio. Lisatud nimekiri "Taastamise ootel" filmidest, mis "Eesti film 100" raames restaureerimist ootavad

  11. Suurlinnakorteri kellavärgiga apelsin / Adrian von Moos

    Index Scriptorium Estoniae

    Moos, Adrian von

    2008-01-01

    Ameerika sisekujundaja Giuseppe Pica New Yorgis asuvast korterist, kus omanik eksponeerib oma kunstikogu ja on sisustamisel püüdnud luua muljet avarusest. Kodune galerii on ka mugav elupaik. 8 värv. vaadet

  12. Tchaikovsky: Symphony No. 5 in E minor, Op. 64 / Jonathan Swain

    Index Scriptorium Estoniae

    Swain, Jonathan

    1994-01-01

    Uuest heliplaadist "Tchaikovsky: Symphony No. 5 in E minor, Op. 64; Rimsky-Korsakov: Russian Easter Festival Overture, Op. 36. Philharmonia Orchestra / Giuseppe Sinopoli; Overture - selected comparison: Gothenburg SO, Järvi (3/91) DG 429984-2GH

  13. Mona Lisa kuulsa naeratuse saladus leidis lahenduse / Johannes Saar

    Index Scriptorium Estoniae

    Saar, Johannes, 1965-

    2004-01-01

    Firenze kunstiajalooõpetaja Giuseppe Pallanti jõudis 25-aastase arhiivitöö tulemusena järeldusele, et Leonardo da Vinci Mona Lisa modelliks on siidikaupmehe Francesco del Giocondo abikaasa Lisa Gerardini

  14. Laser-heated solenoid fusion

    International Nuclear Information System (INIS)

    Vlases, G.C.

    1977-01-01

    Since the suggestion by Dawson, Hertzberg, and Kidder that high-energy CO 2 lasers could be used to heat magnetically confined plasma columns to thermonuclear temperatures, a great deal of theoretical and experimental work has been performed. In this paper we first review the experiments on the basic laser-plasma interaction phenomena, in which lasers with energies up to 1 kJ have been used to produce plasmas at n/sub e/ greater than 10 18 and T/sub e/ greater than 200 eV. The second part reviews fusion reactor studies based on the laser solenoid

  15. Handbook of graph drawing and visualization

    CERN Document Server

    Tamassia, Roberto

    2013-01-01

    Planarity Testing and Embedding Maurizio PatrignaniCrossings and Planarization Christoph Buchheim, Markus Chimani, Carsten Gutwenger, Michael Jünger, and Petra MutzelSymmetric Graph Drawing Peter Eades and Seok-Hee HongProximity Drawings Giuseppe LiottaTree Drawing Algorithms Adrian RusuPlanar Straight-Line Drawing Algorithms Luca VismaraPlanar Orthogonal and Polyline Drawing Algorithms Christian A. Duncan and Michael T. GoodrichSpine and Radial Drawings Emilio Di Giacomo, Walter Didimo, and Giuseppe LiottaCircular Drawing Algorithms Janet M. Six and Ioannis G. TollisRectangular Drawing Algori

  16. Is "Economia Aziendale" Research Programme "Fit for Purpose"? A Commentary on "Contextualizing the Intermediate Financial Accounting Courses in the Global Financial Crisis"

    Science.gov (United States)

    Galassi, Giuseppe

    2011-01-01

    In his commentary, from the perspective of a professor who has spent a lifetime in a highly vocational scientific field like accounting and business economics, Giuseppe Galassi puts forth an alternate proposal to the one suggested in Bloom and Webinger's (2011) article. Bloom and Webinger suggest that disciplines, including management, economics,…

  17. Postimehe žürii hindab võistlusprogrammi filme

    Index Scriptorium Estoniae

    2004-01-01

    Tallinna VIII Pimedate Ööde Filmifestivali võistlusfilme hindab 5-palli süsteemis viis asjatundjat. Seekord põhjendavad oma hinnangut Giuseppe Gariazzo (Tšehhi lavastaja Jan Hrebejki film "Üles-alla") ja Kristiina Davidjants (Taani-Rootsi "Päev ja öö" - režii Simon Staho)

  18. Marijuana for epilepsy?

    OpenAIRE

    Di Giovanni, Giuseppe

    2016-01-01

    Marijuana has been used for centuries for medical reasons. In the early 20th century it was first linked to treatment for epilepsy. Over the last few decades researchers have been unravelling the truth behind the drug. Prof. Giuseppe Di Giovanni tells us more about using marijuana for medical research and his own research on this controversial drug.

  19. Balancing Performance and Sustainability in Next-Generation PMR Technologies for OMC Structures

    Science.gov (United States)

    2016-05-26

    John J. La Scala , Benjamin G. Harvey, Giuseppe R. Palmese, William S. Eck, Joshua M. Sadler, Santosh K. Yadav 5d. PROJECT NUMBER 5e. TASK NUMBER...PERFORMANCE AND SUSTAINABILITY IN NEXT-GENERATION PMR TECHNOLOGIES FOR OMC STRUCTURES Gregory R. Yandek,1 Jason T. Lamb,2 John J. La Scala ,3 Benjamin G

  20. Tuna & täna / Mati Soomre

    Index Scriptorium Estoniae

    Soomre, Mati, 1944-2015

    2006-01-01

    9. märtsil 1842 Milano La Scala teatris esietendunud Giuseppe Verdi ooperi "Nabucco" III vaatuses kõlanud "Orjade koor" sõnad põhinevad Piibli Lauluraamatu 137. laulul, mida on viisistanud paljud heliloojad. 12. märtsil 1946 sündis USA näitleja ja laulja Liza Minelli

  1. Publisher Correction: Quantum engineering of transistors based on 2D materials heterostructures

    Science.gov (United States)

    Iannaccone, Giuseppe; Bonaccorso, Francesco; Colombo, Luigi; Fiori, Gianluca

    2018-06-01

    In the version of this Perspective originally published, in the email address for the author Giuseppe Iannaccone, the surname was incorrectly given as "innaconne"; this has now been corrected in all versions of the Perspective. Also, an error in the production process led to Figs. 1, 2 and 3 being of low resolution; these have now been replaced with higher-quality versions.

  2. UNPUBLISHED TEXTS / INEDITI

    African Journals Online (AJOL)

    User

    Ha pubblicato due libri di traduzioni di poetesse del Rinascimento italiano, ed ha fondato Hesperia Press per la diffusione della poesia italiana moderna. Ha tradotto e pubblicato Maria Luisa Spaziani e Giuseppe Conte. Vive a Milano e a Berkeley, California. Quelle che seguono sono poesie tratte dalle prima sezione della ...

  3. Rahvusooperi Estonia 99. hooaeg algab nädala pärast / Christel Karits

    Index Scriptorium Estoniae

    Karits, Christel, 1966-

    2004-01-01

    Muusikaturu korraldamisest 18. sept. Estonia teatrihoone taga ajaloolisel turuplatsil. Katri Kaasik-Aaslavi ja Vaino Vahingu näidendi "Teatriromanss" (muusika arranzheerija ja pianist Olav Ehala) esietendusest Estonia kammersaalis 22. oktoobril. Giuseppe Verdi ooperi "Aida" etendamisest Rocca al Mare Onistar Tennisekeskuses 8.-10., 12.-17. oktoobril

  4. Maailm meie jalge all / Philippe Dayan

    Index Scriptorium Estoniae

    Dayan, Philippe

    2007-01-01

    Jalatsidisainerite Stuart Weitzman'i (USA), Jimmy Choo (Inglismaa), Manolo Blahnik'i (USA), Georgina Goodman'i (Inglismaa), Franziska Hübener'i (Brasiilia), Edmundo Castillo (Itaalia), Christian Louboutin'i (Prantsusmaa), Giuseppe Zanotti (Itaalai), Bruno Frisoni (Prantsusmaa), Pierre Hardy (Prantsusmaa) eluloolisi andmeid ja loomingu lühitutvustus

  5. 15-00366_SI_NP.doc

    Indian Academy of Sciences (India)

    IRAN SHEIKHSHOAIE a, S YOUSEF EBRAHIMIPOURa,*, MAHDIEH SHEIKHSHOAIEa, MARYAM MOHAMADIa,b, MEHDI ABBASNEJADc, HADI AMIRI RUDBARId and GIUSEPPE BRUNOe. a Department of Chemistry, Faculty of Science, Shahid Bahonar University of Kerman, Kerman, Iran. bDepartment of Chemistry, ...

  6. Science | AAAS

    Science.gov (United States)

    Giuseppe Conte Italy's new prime minister defended discredited stem cell therapy By Luca Tancredi Barone defended discredited stem cell therapy By Luca Tancredi Barone May. 24, 2018 illustration of GOES-17 | May. 24, 2018 STEPHAN JUNEK/MPI BRAIN RESEARCH Apparatus for building a single NaCs molecule from two

  7. Water SA - Vol 43, No 2 (2017)

    African Journals Online (AJOL)

    Sensitivity to selected contaminants in a biological early warning system using Anodonta woodiana (Mollusca) · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Luisa Giari, Fabio Vincenzi, Elisa Anna Fano, Ivano Graldi, Fernando Gelli, Giuseppe Castaldelli, 200-208.

  8. Workshop on III-V Integrated Optoelectronics Held in Hilton Head, South Carolina on 28-30 March 1989

    Science.gov (United States)

    1990-01-01

    Barney De Loach AT&T Bell Laboratories MH 2D-351 600 Mountain Avenue Murray Hill, NJ 07974 Tel: 201-582-3382 Fax: 201-582-2451 Dr. M.A. Di Giuseppe AT...Park, NC 27709-2211 Tel: 919-549-0641 Fax: 919-549-9399 Professor T. Ken Gustafson Department of Electrical Engineering and Computer Sciences

  9. Bagatellid : maailm / Mirjam Tally

    Index Scriptorium Estoniae

    Tally, Mirjam, 1976-

    2008-01-01

    Bachi ja Mozarti uued ilmed. Hilary Hahnilt ja Mayuko Kamiolt uued plaadid. Lahkus tenor Giuseppe di Stefano. Henri Dutilleux pälvis Kuningliku Filharmooniaühingu kuldmedali. Inglismaa vanim spinett müügil. Guarneri hinnaline viiul helises taas

  10. Il respiro della rosa quando la poesia genera sapienza | Maggiari ...

    African Journals Online (AJOL)

    Massimo Maggiari's first collection of poems is entitled Terre lontane / Lands Away (Campanotto, 1999) with an introduction by Giuliano Manacorda and afterword by Giuseppe Conte (Italo Alghiero Chiusano Award, Frascati 1999). His poems were published in Austria in The Poet's Voice, in South Africa in Italian Studies in ...

  11. At the Omega Facility

    CERN Multimedia

    1977-01-01

    Behind the large gas Cerenkov counter (not visible) one gets ready for the WA4 experiment. On the left stands a large scintillator hodoscope. On the right, lead-glass counters are fitted into their support. Giuseppe Marinoni (centre) and Alois Sigrist (right).

  12. Uudised

    Index Scriptorium Estoniae

    2006-01-01

    Giuseppe Verdi ooperi "Maskiball" uuslavastusest Malmös. Kantrilaulja Willie Nelsoni heliplaadist "Cowboys are Frequently Secretly". Helilooja Gustav Mahleri lapselaps Marina Mahler nõuab Austria Galeriilt tagasi Edvard Munchi maali "Suveöö rannas". Jamaical Kingstonis asuvast reggae-laulja Bob Marley sünnimajast, kus asuvad helistuudio ja muuseum

  13. Browse Title Index

    African Journals Online (AJOL)

    L Somigli. Vol 22, No 2 (2009), Antropologia di un intellettuale, Giuseppe Cassieri, Abstract PDF. G Sotis. Vol 14, No 2 (2001), Apprendere una lingua straniera: tempo e spazio nella cultura italiana, Abstract PDF. C Samson. Vol 26, No 1 (2013), Appunti pasoliniani per un'orestiade africana, Abstract PDF. M Chiacchiararelli.

  14. Questioning the 'exotic' in two Italian travellers' accounts of New ...

    African Journals Online (AJOL)

    L'articolo studia le testimonianze di due missionari italiani presenti in Nuova Zelanda tra la fine dell'Ottocento e l'inizio del Novecento: il benedettino Dom Felice Vaggioli e il salesiano Giuseppe Capra. Sia l'uno sia l'altro, attratti dalle bellezze naturali del paese descritto come una sorta di esotico nuovo Eden, finirono col ...

  15. Ooperiaasta võimas algus / Tarmo Virki

    Index Scriptorium Estoniae

    Virki, Tarmo

    2003-01-01

    Einojuhani Rautavaara uue ooperi "Rasputin" esietendusest Soome Rahvusooperis 19. sept. (dirigent Mikko Franck) ja etendustest 22., 24., 27. ja 30. sept. ning 3., 6., 9. ja 11. oktoobril. Giuseppe Verdi "Trubaduur" 11., 17. ja 20. sept ning 1. okt., dirigent Eri Klas. Leosh Janaceki "Katja Kabanova" esietendusest 12. detsembril

  16. Dalla grammatica alla pratica della lingua. Approcci linguistici medievali e umanistici

    Directory of Open Access Journals (Sweden)

    Minne Gerben de Boer

    2016-09-01

    Full Text Available Recensione diLa pratica e la grammatica. Problemi, modelli e percorsi di formazione linguistica tra Duecento e Cinquecento, a cura di Franco Pierno e Giuseppe Polimeni, Paris, Classiques Garnier, 2014 (numero speciale di Cahiers de recherches médiévales et humanistes-Journal of Medieval and Humanistic Studies, 2/28, pp. 13-234, ISBN: 9782812445675.

  17. More and more together : Legal family formats for same-sex and different-sex couples in European countries – Comparative analysis of data in the LawsAndFamilies Database

    NARCIS (Netherlands)

    Waaldijk, C.

    2017-01-01

    This report (edited by Kees Waaldijk) includes contributions by Daniel Damonzé, Marie Digoix, Marina Franchi, Natalie Nikolina, José Ignacio Pichardo Galán, Giulia Selmi, Matias de Stéfano Barbero, Matthias Thibeaud, Jose A.M. Vela, Kees Waaldijk, and Giuseppe Zago. This report offers a

  18. Carbon dioxide as chemical feedstock

    National Research Council Canada - National Science Library

    Aresta, M

    2010-01-01

    ... Dioxide as an Inert Solvent for Chemical Syntheses 15 Alessandro Galia and Giuseppe Filardo Introduction 15 Dense Carbon Dioxide as Solvent Medium for Chemical Processes 15 Enzymatic Catalysis in Dense Carbon Dioxide 18 Other Reactions in Dense Carbon Dioxide 19 Polymer Synthesis in Supercritical Carbon Dioxide 20 Chain Polymerizations: Synt...

  19. Postimees hääletas võitjaks Korea filmi "Tühi maja"

    Index Scriptorium Estoniae

    2004-01-01

    Tallinna VIII Pimedate Ööde Filmifestivali võistlusfilme hindas 5-palli süsteemis viis asjatundjat : Sulev Teinemaa, Kristiina Davidjants, Olev Remsu, Jaak Allik Ja Giuseppe Gariazzo. Kõik esitavad oma hinnangu lühikokkuvõtte. Lisatud lõplik tabel

  20. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics; Volume 89; Issue 3. Issue front cover thumbnail. Volume 89, Issue 3. September 2010, pages 269-390. Special issue - How is sex determined in insects? pp 269-270. Preface · J. Nagaraju Giuseppe Saccone · More Details Fulltext PDF. pp 271-277 Review Article. The role of the ...

  1. 76 FR 15209 - 150th Anniversary of the Unification of Italy, 2011

    Science.gov (United States)

    2011-03-21

    ... fighting for the preservation of our own Union, Giuseppe Garibaldi's campaign for the unification of Italy... millions of American women and men of Italian descent who strengthen and enrich our Nation. Italy and the... thousand eleven, and of the Independence of the United States of America the two hundred and thirty-fifth...

  2. Two-factor theory – at the intersection of health care management and patient satisfaction

    Science.gov (United States)

    Bohm, Josef

    2012-01-01

    Using data obtained from the 2004 Joint Canadian/United States Survey of Health, an analytic model using principles derived from Herzberg’s motivational hygiene theory was developed for evaluating patient satisfaction with health care. The analysis sought to determine whether survey variables associated with consumer satisfaction act as Hertzberg factors and contribute to survey participants’ self-reported levels of health care satisfaction. To validate the technique, data from the survey were analyzed using logistic regression methods and then compared with results obtained from the two-factor model. The findings indicate a high degree of correlation between the two methods. The two-factor analytical methodology offers advantages due to its ability to identify whether a factor assumes a motivational or hygienic role and assesses the influence of a factor within select populations. Its ease of use makes this methodology well suited for assessment of multidimensional variables. PMID:23055755

  3. Two-factor theory - at the intersection of health care management and patient satisfaction.

    Science.gov (United States)

    Bohm, Josef

    2012-01-01

    Using data obtained from the 2004 Joint Canadian/United States Survey of Health, an analytic model using principles derived from Herzberg's motivational hygiene theory was developed for evaluating patient satisfaction with health care. The analysis sought to determine whether survey variables associated with consumer satisfaction act as Hertzberg factors and contribute to survey participants' self-reported levels of health care satisfaction. To validate the technique, data from the survey were analyzed using logistic regression methods and then compared with results obtained from the two-factor model. The findings indicate a high degree of correlation between the two methods. The two-factor analytical methodology offers advantages due to its ability to identify whether a factor assumes a motivational or hygienic role and assesses the influence of a factor within select populations. Its ease of use makes this methodology well suited for assessment of multidimensional variables.

  4. Theoretical estimation of Z´ boson mass

    International Nuclear Information System (INIS)

    Maji, Priya; Banerjee, Debika; Sahoo, Sukadev

    2016-01-01

    The discovery of Higgs boson at the LHC brings a renewed perspective in particle physics. With the help of Higgs mechanism, standard model (SM) allows the generation of particle mass. The ATLAS and CMS experiments at the LHC have predicted the mass of Higgs boson as m_H=125-126 GeV. Recently, it is claimed that the Higgs boson might interact with dark matter and there exists relation between the Higgs boson and dark matter (DM). Hertzberg has predicted a correlation between the Higgs mass and the abundance of dark matter. His theoretical result is in good agreement with current data. He has predicted the mass of Higgs boson as GeV. The Higgs boson could be coupled to the particle that constitutes all or part of the dark matter in the universe. Light Z´ boson could have important implications in dark matter phenomenology

  5. Sugli studi medievali e il mutamento digitale On the medieval studies and the digital change

    Directory of Open Access Journals (Sweden)

    Redazione Reti Medievali (a cura di

    2004-12-01

    Full Text Available

    La sezione raccoglie tre brevi comunicazioni, tenute nell’ambito del seminario Medium-Evo. Gli studi medievali e il mutamento digitale (Firenze, 2001 e dedicate rispettivamente ai periodici e alle forme di comunicazione del sapere (Giorgio Chittolini, al problema del reperimento delle risorse e della repertoriazione delle fonti (Paolo Delogu, ai contraccolpi dell’uso del mezzo informatico sulla scrittura della storia (Giuseppe Sergi.

    This section includes three short papers - presented at the seminar on Medium-Evo. Gli studi medievali e il mutamento digitale (Firenze, 2001 (Medium-Evo. Medieval studies and the digital change - which are respectively focused on periodicals, different types of learning communication (Giorgio Chittolini, problems linked to document searching and filing (Paolo Delogu, backlashes  coming from the use of computer in writing history (Giuseppe Sergi.

  6. Passions au miroir: Hugo et Garibaldi dans la solitude de l’Histoire

    Directory of Open Access Journals (Sweden)

    Marco Nuti

    2009-12-01

    Full Text Available In Mythic Imagery, a warrior is a hybrid man – a divine human being or a divinized mortal – who stands out of his own kind for his extraordinary skill to generate power. Being an undefined figure of man, equidistant from deity and humanity, the warrior hero represents the Human Community. Using his knowledge of what Giuseppe Garibaldi had done to unify Italy, Victor Hugo had the chance to annex to his political and literary fighting a contemporary hero who shared his own ideology. An amazing relationship put their destinies together, and the epistolary exchange Garibaldi (1863 strengthened this union. Giuseppe Garibaldi in Mentana (1867 is invested with the heroic legitimacy of a symbolical progressive movement. The experimental brotherhood between the poet and the warrior symbolized for Hugo a continuous questioning of the real power of poetical language.

  7. U.S. Military Technology Dependence: The Hidden Vulnerability to National Security

    Science.gov (United States)

    2016-06-10

    Wiebe Eco . Vulnerability in Technological Cultures. Maastricht University, 2009. Caforio, Giuseppe. Handbook of the Sociology of the Military...10-06-2016 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER U.S. MILITARY TECHNOLOGY DEPENDENCE: THE HIDDEN Sb. GRANT NUMBER VULNERABILITY TO NATIONAL...14. ABSTRACT Because the U.S. has a technological culture, the U.S. military has become technology dependent. This dependence has made the military

  8. Red wine and cardiovascular health the "French Paradox" revisited

    OpenAIRE

    Giuseppe Lippi; Massimo Franchini; Gian Cesare Guidi

    2010-01-01

    Giuseppe Lippi1, Massimo Franchini2, Gian Cesare Guidi31U.O. di Diagnostica Ematochimica, 2Servizio di Immunoematologia e Trasfusione, Dipartimento di Patologia e Medicina di Laboratorio, Azienda Ospedaliero, Universitaria di Parma, Parma, Italy; 3Sezione di Chimica Clinica, Dipartimento di Scienze Morfologico-Biomediche, Università degli Studi di Verona, Verona, ItalyAbstract: The healthful and nutritive properties of wine have been acknowledged for thousands of years, but the obs...

  9. JPRS Report, West Europe.

    Science.gov (United States)

    1987-07-15

    Piero Benetazzo; LA REPUBBLICA, 15 May 87) 43 NORWAY Poll Shows Most Support for Labor Party Government (AFTENPOSTEN, 18, 19 May 87) 46...Control of Fiat, IFI (Giuseppe Turani; LA REPUBBLICA, 8 May 87) 104 NORWAY Economists Urge Continuing Measures To Hold Line on Budget (AFTENPOSTEN...themselves which enterprise will be the next one to close down after the closing down of the chlorine production at the Soya Bean Cake Factory in

  10. Fast Algorithms for Earth Mover Distance Based on Optimal Transport and L1 Regularization II

    Science.gov (United States)

    2016-09-01

    gradient ascent in the dual variable Φ and a gradient descent in the primal variable m. In our updates for (6), we use simple exact formulae. Since the...0. References [1] Luigi Ambrosio, Nicola Gigli, and Giuseppe Savaré. Gradient flows: in metric spaces and in the space of probability measures...continuity and summability of transport densities: simpler proofs and new estimates. Calculus of Variations and Partial Differential Equations, 36 (3

  11. La scala Mercalli

    OpenAIRE

    Tertulliani, A.

    2004-01-01

    Quando vi erano pochi strumenti per registrare e misurare i terremoti, alla fine dell'Ottocento, i sismologi stimavano la grandezza di un terremoto osservandone gli effetti, come ad esempio il crollo di un comignolo o la caduta di un ponte. Il sismologo Giuseppe Mercalli fu tra i primi a classificare i terremoti in base ai loro effetti definendo una scala dell’intensità o degli effetti Macrosismici.

  12. Co mohou vypovědět pozůstalostní spisy na případu W. A. Mozarta a Josefy Duškové

    Czech Academy of Sciences Publication Activity Database

    Jonášová, Milada

    2017-01-01

    Roč. 27, č. 12 (2017), s. 39-41 ISSN 1210-8081 Institutional support: RVO:68378076 Keywords : estate * personal libraries * Joseph Haydn * Giuseppe Verd * W. A. Mozart * Josefa Dušková * W. A. Mozart * Josefa Dušková * personal libraries * estate * last will * furniture Subject RIV: AL - Art, Architecture, Cultural Heritage OBOR OECD: Performing arts studies (Musicology, Theater science, Dramaturgy)

  13. Clinical features and imaging findings in a case of Capgras syndrome

    OpenAIRE

    Luca M; Bordone A; Luca A; Patti A; Sortino G; Calandra C

    2013-01-01

    Maria Luca,1 Andrea Bordone,1 Antonina Luca,2 Andrea Patti,1 Giuseppe Sortino,3 Carmela Calandra11Department of Medical and Surgery Specialties, Psychiatry Unit, 2Department GF Ingrassia, Section of Neuroscience, 3Department of Diagnostic Imaging, Radiology Unit, University Hospital Policlinico-Vittorio Emanuele, Catania, Sicily, ItalyAbstract: Capgras syndrome consists of the delusional belief that a person or persons have been replaced by doubles or impostors. It can occur in the context of...

  14. Coronary artery disease in Africa and the Middle East

    OpenAIRE

    Almahmeed, Wael; Arnaout. M.Samir,M.Samir; Chettaoui,; Ibrahim,; Kurdi,; Taher,; Mancia,Giuseppe

    2012-01-01

    Wael Almahmeed1, Mohamad Samir Arnaout2, Rafik Chettaoui3, Mohsen Ibrahim4, Mohamed Ibrahim Kurdi5, Mohamed Awad Taher6, Giuseppe Mancia71Heart and Vascular Institute, Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates; 2American University of Beirut Medical Center, Beirut, Lebanon; 3General and Cardiovascular Clinic of Tunis, Tunisia; 4Cairo University, Cairo, Egypt; 5King Khalid University Hospital and The Kingdom Hospital, Saudi Arabia; 6Ain Shams University School of Medicine, C...

  15. The melatonergic system: effects on sleep and implications for the treatment of psychiatric disorders

    OpenAIRE

    De Berardis, Domenico

    2011-01-01

    Domenico De Berardis1,2, Tiziano Acciavatti1, Giuseppe Di Iorio1, Mariangela Corbo1, Nicola Serroni2, Daniela Campanella2, Fabiola Di Emidio2, Monica Piersanti3, Marilde Cavuto4, Giovanni Martinotti5, Francesco Saverio Moschetta2, Massimo Di Giannantonio11Department of Neurosciences and Imaging, Chair of Psychiatry, University “G. D'Annunzio”, Chieti; 2NHS, Department of Mental Health, Psychiatric Service of Diagnosis and Treatment, Hospital “G. Mazzini&a...

  16. The influence of parenting on maladaptive cognitive schema: a cross-sectional research on a group of adults

    OpenAIRE

    Pellerone,Monica; Iacolino,Calogero; Mannino,Giuseppe; Formica,Ivan; Zabbara,Simona

    2017-01-01

    Monica Pellerone,1 Calogero Iacolino,1 Giuseppe Mannino,2 Ivan Formica,3 Simona Maria Zabbara1 1Faculty of Human and Social Sciences, “Kore” University of Enna, Enna, Sicily, Italy; 2Department of Jurisprudence, “LUMSA” University, Rome, Italy; 3Department of Cognitive, Psychological, Pedagogical Sciences and Cultural Studies, University of Study of Messina, Messina, Sicily, Italy Background: The literature emphasizes the role of early interpersonal exp...

  17. Evaluation of effectiveness and safety of a herbal compound in primary insomnia symptoms and sleep disturbances not related to medical or psychiatric causes

    OpenAIRE

    Palmieri, Giancarlo; Contaldi, Paola; Fogliame, Giuseppe

    2017-01-01

    Giancarlo Palmieri,1,2 Paola Contaldi,1 Giuseppe Fogliame1 1ANARDI Medical and Scientific Association, Scafati, Italy; 2Department of Internal Medicine, Niguarda Cà Granda Hospital, Milan, Italy Background and purpose: Sleep disturbances and related daytime activities impairment are common diseases nowadays. General practitioners are often the first health care professional asked to alleviate sleep disturbances and primary insomnia symptoms. Beyond a wide class of hypnotic drugs, ...

  18. Prevention of diabetic eye disease: the commonest cause of blindness in individuals younger than 65 years

    OpenAIRE

    Tatti, Patrizio

    2010-01-01

    Patrizio Tatti1, Patrizia Di Mauro1, Leonardo Masselli1, Adriano Longobardi2, Annabel Barber31Diabetes and Endocrinology Department, 2UOS Eye Surgery, Ospedale S Giuseppe, ASL RMH, Rome, Italy; 3University of Nevada School of Medicine, Las Vegas, NV, USAAbstract: There has been a considerable advancement in the treatment of diabetes and understanding of the biochemical mechanisms underlying diabetic complications in the last 20 years. However, this advancement has not translated into a consis...

  19. Soccer practice as an add-on treatment in the management of individuals with a diagnosis of schizophrenia

    OpenAIRE

    Battaglia, Giuseppe; Alesi, Marianna; Inguglia, Michele; Roccella, Michele; Caramazza, Giovanni; Bellafiore, Marianna; Palma, Antonio

    2013-01-01

    Giuseppe Battaglia,1,3 Marianna Alesi,2 Michele Inguglia,4 Michele Roccella,2 Giovanni Caramazza,3 Marianna Bellafiore,1,3 Antonio Palma1,3 1Department of Law, Social and Sport Science, University of Palermo, Palermo, Italy; 2Department of Psychology, University of Palermo, Palermo Italy; 3Regional Sports School of CONI Sicilia, Sicily, Italy; 4Local Health of Palermo, Palermo, Italy Abstract: Physical activity is an important aspect of good health for everyone; it is even more important for...

  20. Chemical Reactions at the in vacuo Au/InP Interface.

    Science.gov (United States)

    1987-07-25

    Phys. C: Solid State Phys. 10, 4545 (1977). 2 A. Hiraki, K. Shuto, S. Kim, W. Kanmnura, and M. Iwami, Appl.Phys. Letts. 31, 611 (1977). 3. P.W. Chye ...Pelous, and P. Henoc, J.Appl.Phys. 52, 5112 (1981). 13. 1. Camlibel, A.K. Chin , F. Ermanis, M.A. DiGiuseppe, J.A. Lourenco and W.A. Bonner

  1. La laicità contesa. Aspetti della crisi politica turca

    Directory of Open Access Journals (Sweden)

    Matteo Prandi

    2011-06-01

    Full Text Available Il contributo è segnalato dal Prof. Giuseppe Casuscelli. SOMMARIO: 1. Introduzione – 2. Per una prima ricostruzione fattuale della crisi politica turca nel biennio 2007-2008 – 3. Il giudizio sullo scioglimento del partito AKP: le argomentazioni delle parti – 4. La sentenza della Corte costituzionale del 30 luglio 2008. La Corte tra funzione di equilibrio e difesa del laicismo – 5. Cenni conclusivi, nella prospettiva del diritto ecclesiastico europeo.

  2. The XX century architectural heritage in the Marche region. The Masters’ drawings and designs.

    Directory of Open Access Journals (Sweden)

    Ramona Quattrini

    2010-12-01

    Full Text Available In the history of architecture, Marche is often considered as a region that did not take part in the big developments of national architecture. Hence it’s meaningful to examine the architectonic events of the Region in the XX century and how much the Marche region has been the object of work by the great masters of the past century. A list of architects - called ‘masters’ – has been selected: Franco Albini, Gae Aulenti, Carlo Aymonino, Ernesto Basile, BBPRGuido Canella, Giancarlo De Carlo, Luigi Figini, Massimiliano Fuksas, Roberto Gabetti, Ignazio Gardella, Giorgio Grassi, Vittorio Gregotti, Adalberto Libera, Giovanni Michelucci, Gaetano Minnucci, Carlo Mollino, Luigi Moretti, Pier Luigi Nervi, Giuseppe Pagano, Edoardo Persico, Marcello Piacentini, Renzo Piano, Gio Ponti, Paolo Portoghesi, Franco Purini, Ludovico Quaroni, Mario Ridolfi, Aldo Rossi, Giuseppe Samonà, Antonio Sant’Elia; Alberto Sartoris, Carlo Scarpa, Giuseppe Terragni, Gino Valle, Vittoriano Viganò, Marco Zanuso, The research is a meaningful census of the works of the 20th century, whether they have been realized or not (projects, competitions, studies etc. and assigned to the masters listed above.

  3. Propos autour d’un inventaire : quelques peintures italiennes à Bastia

    Directory of Open Access Journals (Sweden)

    Michel-Edouard Nigaglioni

    2005-09-01

    Full Text Available Du Moyen Age à la fin du XVIIIe siècle, Bastia fut une ville italienne dépendant de la république de Gênes. C’est pourquoi les églises de la ville conservent encore nombre de toiles d’artistes génois (Ottavio Cambiaso, Domenico Piola, Giuseppe Badaracco ou provenant de régions italiennes proches de la Corse (Giovanni Bilivert. En 1844, le legs du cardinal Fesch, oncle de Napoléon, fait entrer dans les collections municipales une centaine de tableaux italiens. Des restaurations récentes (Lavinia Fontana et une reconsidération globale du fonds, rendue possible par l’inventaire du mobilier appartenant à la ville, permettent découvertes et propositions d’attribution (Francesco Brizio, Giuseppe Bonito….From the Middle Ages up to the end of the eighteenth century, Bastia was an Italian city belonging to the Republic of Genoa. This is why the churches of the city conserve several paintings by artists of Genoese origin (Ottavio Cambiaso, Domenico Piola, Giuseppe Badaracco or coming from other regions in Italy close to Corsica (Giovanni Bilivert. In 1844, a bequest by Cardinal Fesch (Napoleon’s uncle also brought about a hundred Italian paintings to the collections of the city. Some recent restoration work (Lavinia Fontana and a new, general view of the corpus of paintings, helped by the inventory of the furniture belonging to the city, has given rise to some discoveries and also allows for the authors of certain paintings to be identified (Francesco Brizio, Guiseppe Bonito….

  4. Motivations, concerns, and expectations of Scandinavian health professionals volunteering for humanitarian assignments.

    Science.gov (United States)

    Bjerneld, Magdalena; Lindmark, Gunilla; McSpadden, Lucia Ann; Garrett, Martha J

    2006-01-01

    International nongovernmental organizations (NGOs) involved in humanitarian assistance employ millions of volunteers. One of the major challenges for the organizations is the high turnover rate among their personnel. Another is recruiting the right persons. As part of a series of studies investigating factors that affect the recruitment process and the success of assignment, this qualitative study examined health professionals' motivations for volunteering, their various concerns, and their expectations about themselves and the organizations for which they would work. The findings from focus group interviews with potential humanitarian volunteers were considered within the framework of Hertzberg's theory of motivations and Maslow's hierarchy of needs. The study has significant implications for personnel policy and practice in the humanitarian sector. Recruitment officers should have the self-actualized person, as described by Maslow, in mind when interviewing candidates. This perspective would make it easier for them to understand the candidates' thoughts and concerns and would lead to more effective interventions. Program officers should have satisfiers and dissatisfiers, as identified by Herzberg, in mind when planning programs. The probability that personnel will leave humanitarian work is lower if they perceive working conditions as good.

  5. The worker profile autocontrolled

    Directory of Open Access Journals (Sweden)

    Jairo Omar Delgado Mora

    2015-06-01

    Full Text Available This document is part of two deliveries. In this first paper is to make an approach to the concept of self-control from the very beginning with Sakichi Toyoda, founder of what the industry Toyota Motor Company, additionally taking some excerpts of the concept issued by teachers and the psychologist Henry Murray, a professor at the university Harvard precursor test TAT personality test creator, pen applied world wide by psychologists David McCllelan, also a psychologist and a pioneer in the study of human needs and the concept of competence; Professor Jeffrey Pfeffer of Stanford University organizational behavior and theory, Frederick Hertzberg, Psychologist and strong influential in business management, Kronfly Cruz, lawyer and investigator of social and administrative sciences, Charles Perrow, a sociologist at Yale University and Stanford , who studies the impact of large organizations in society, among others. The study reflects the need to meet organizational objectives related to the physicochemical characteristics of the finished product in a plant of the company’s main beers in the country. In this paper, we intend to make an approximation of worker self -controlled, which when compared with the powers, generic, specific and technical area established by the brewery, will allow generating a methodology to adjust these competencies and to obtain the target profile drawn. This comparison and development of the methodology proposed is the subject of the second work planned.

  6. Series lecture on advanced fusion reactors

    International Nuclear Information System (INIS)

    Dawson, J.M.

    1983-01-01

    The problems concerning fusion reactors are presented and discussed in this series lecture. At first, the D-T tokamak is explained. The breeding of tritium and the radioactive property of tritium are discussed. The hybrid reactor is explained as an example of the direct use of neutrons. Some advanced fuel reactions are proposed. It is necessary to make physics consideration for burning advanced fuel in reactors. The rate of energy production and the energy loss are important things. The bremsstrahlung radiation and impurity radiation are explained. The simple estimation of the synchrotron radiation was performed. The numerical results were compared with a more detailed calculation of Taimor, and the agreement was quite good. The calculation of ion and electron temperature was made. The idea to use the energy more efficiently is that one can take X-ray or neutrons, and pass them through a first wall of a reactor into a second region where they heat the material. A method to convert high temperature into useful energy is the third problem of this lecture. The device was invented by A. Hertzberg. The lifetime of the reactor depends on the efficiency of energy recovery. The idea of using spin polarized nuclei has come up. The spin polarization gives a chance to achieve a large multiplication factor. The advanced fuel which looks easiest to make go is D plus He-3. The idea of multipole is presented to reduce the magnetic field inside plasma, and discussed. Two other topics are explained. (Kato, T.)

  7. Mechanical effects of strong measurement: back-action noise and cooling

    Science.gov (United States)

    Schwab, Keith

    2007-03-01

    Our recent experiments show that it is now possible to prepare and measure mechanical systems with thermal occupation factors of N˜25 and perform continuous position measurements close to the limits required by the Heisenberg Uncertainty Principle (1). I will discuss our back-action measurements with nanomechanical structures strongly coupled to single electron transistors. We have been able to observe the stochastic back-action forces exerted by the SET as well as a cooling effect which has analogies to cooling in optical cavities. Furthermore, I will discuss progress using optical fields coupled to mechanical modes which show substantial cooling using the pondermotive effects of the photons impacting a flexible dielectric mirror (2). Both of these techniques pave the way to demonstrating the true quantum properties of a mechanical device: squeezed states, superposition states, and entangled states. (1) ``Quantum Measurement Backaction and Cooling Observed with a Nanomechanical Resonator,'' A. Naik, O. Buu, M.D. LaHaye, M.P. Blencowe, A.D. Armour, A.A. Clerk, K.C. Schwab, Nature 443, 193 (2006). (2) ``Self-cooling of a micro-mirror by radiation pressure,'' S. Gigan, H.R. Boehm, M. Patemostro, F. Blaser, G. Langer, J. Hertzberg, K. Schwab, D. Baeuerle, M. Aspelmeyer, A. Zeilinger, Nature 444, 67 (2006).

  8. Microprocessing in European High Energy Physics Experiments - ECFA Working Group on Data Processing Standards - Report of the Microprocessor Subgroup May 1982

    CERN Document Server

    European Committee for Future Accelerators (ECFA)

    1982-01-01

    This document contains two reports on the use of microprocessors in European High-Energy Physics experiments. The first is a presentation of data collected by a sub-group of the ECFA working group on data procesing standards. The working group is organised by E. Lillestol, University of Bergen and E.M. Rimmer, CERN, DD Division; the Microprocessor sub-group organiser is L.O. Hertzberger, NIKHEF, Amsterdam. Data are given from projects numbered 81 - 194, and some CERN projects are included. Even though there is some duplication of information, a second report has been appended which covers a wider range of CERN projects. This was the result of a microprocessor survey made at CERN by P. Scharff-Hansen, DD Division, at the request of E. Gabthuler. The ECFA working group intends to have reports for all the sub-groups (10 in number) available in machine-readable form at the CERN computer centre. However, it was felt that the information herein is most valuable to designers and users of microprocessors, and that it...

  9. Fuels, energy, and the environment

    CERN Document Server

    Karim, Ghazi A

    2012-01-01

    All complicated materials of combustion science are presented in a very clear and precise manner … This is the book, in my opinion, that every combustion, fire safety, and fuel engineer should have. … equally useful to newcomers … [and] experienced professionals and researchers in the area.-S.O. Bade Shrestha, Western Michigan University The book covers all aspects of fuels, not just … chemistry or combustion. Of particular importance and actuality are those issues related to safety and environmental impact. Furthermore, the variety of fuels and processes discussed is very wide.-Giuseppe Spazz

  10. The Force of Destiny: a parody orchestrated with mastery by Nélida Piñon.

    Directory of Open Access Journals (Sweden)

    Neiva Kampff Garcia

    2009-12-01

    Full Text Available The present work is an analytic reading of the novel The Force of Destiny, by Nélida Piñon, which was published in 1978 an has a theme that dialogues with the opera of same title composed in 1861 by Giuseppe Verdi. My proposal consists in assuming a spectators’ glance towards the presentation of this parody that is written in prose but that parades before us theatre and operatically, allowing us to know the mastery of a conductor that uses the language baton to lead us through the universe of imagination.

  11. LE PRIME TRADUZIONI ROMANZE DEL “CAPPOTTO” DI GOGOL’: PRECISAZIONI CRONOLOGICHE E TRADUTTOLOGICHE

    Directory of Open Access Journals (Sweden)

    Olga INKOVA

    2016-11-01

    Full Text Available This paper analyzes the first Italian translation of Gogol's short story "The Coat," published 1903 by Giuseppe Loschi. Its comparison with the French translation of Léon Golschmann and Ernest Jaubert (1896 shows that G. Loschi was clearly inspired by the latter: the literal coincidences, lexical and syntactic, the same changes and reductions of the original text and the same mistakes cannot be random. But the Italian translator is even more radical, stopping the narrative at the death of the protagonist and favoring an ethical-religious, moralizing reading of the work of Gogol.

  12. [Constant Duméril (1774-1860) anatomist doctor and naturalist, about a portrait by G. Devers].

    Science.gov (United States)

    Le Floch-Prigent, P

    2008-12-01

    André, Marie, Constant Duméril (1774-1860) served as a professor in the from 1801 to 1855. He was also chairman of herpetology and ichthyology of the in Paris. The Paris-Descartes University (department of anatomy) owns a great, framed portrait which is an oil painting by Giuseppe Devers, 1855, representing C. Duméril sat on a chair. The study of his portrait, biography and bibliography brings precisions on a noticeable scholar of the anatomical and naturalistic field in Paris in the first half of the 19th century.

  13. One of the two end-cap vacuum chambers for the CMS experiment has been completed.

    CERN Multimedia

    Maximilien Brice

    2005-01-01

    This 7.5-metre-long cone-shaped object is the fruit of many years' development and its machining and assembly were performed with the utmost precision. Part of the team involved in the design and production of the end-cap vacuum chamber for CMS, standing behind the completed segment. Picture 02 from left to right : Thierry Tardy (TS/MME), Luigi Leggiero (TS/MME), Patrick Lepeule (AT/VAC), Gérard Faber (ETH Zürich), Stefano Bongiovani (CINEL Project Manager), Giuseppe Foffano (TS/MME) and Marc Thiebert (TS/MME).

  14. Université de Genève | Séminaire de physique corpusculaire | 26 February

    CERN Multimedia

    2014-01-01

    Neutrino physics in the Planck era, Prof. Gennaro Miele, University of Naples   Wednesday 26 February 2014, 11:15 a.m. Science III, Auditoire 1S081 Boulevard d’Yvoy, 1211 Genève 4 Abstract: I briefly summarize the status of art about the properties of relic neutrino distributions and the implications of different neutrino scenarios on cosmological observables after the first measurements by Planck. In particular, I will pay particular attention to the effects due to neutrino-antineutrino asymmetry and to the presence of sterile degrees of freedom. Organised by Prof. Teresa.Montaruli@unige.ch and Prof. Giuseppe.Iacobucci@unige.ch. More information here.

  15. Rilievi in sella a un quad

    Directory of Open Access Journals (Sweden)

    Fulvio Bernardini

    2013-12-01

    Full Text Available Renewable energy—including biomass, geo- thermal, hydroelectric,wind and solar—is big business in Italy. Solar farms able toproduce 1 MW or more of nominal power are considered “large.”Before installing such a PV plant, an acc urate topographical surveyof the ground is required. Giuseppe Greco is known in Italyas an expert in surv eying areas that are extensive and difficult toacc ess. This is because he works with the help of a quad all-terr ainvehicle (AT V, a Segway personal transporter and a personal electricrobotic cart for moving his equipment.

  16. Power Over Ethernet – a solução de vanguarda nas comunicações baseadas em IP

    OpenAIRE

    Ramos, Sérgio

    2013-01-01

    Mal sabia o Italiano Antonio Santi Giuseppe Meucci na segunda metade do século XIX (1870-1876), que a sua invenção iria alcançar um êxito sem precedente e que mudaria por completo o estilo de vida das gerações vindouras: o “Telettrofono” (telégrafo falante). Porém, e por necessidade, acabou por vender o protótipo e seus respetivos direitos, a Alexander Graham Bell, o qual ficou historicamente conhecido como o inventor do telefone. Com efeito, o telefone quase que dispe...

  17. Andrea Caracausi e Antonio Conzato (a cura di) (2013). Formazione alla politica, politica della formazione a Venezia in Età moderna

    OpenAIRE

    Giani, Marco

    2015-01-01

    Il volume raccoglie gli Atti del Convegno svoltosi nel maggio 2011 presso l’Università di Padova, avente come tema «La formazione dei ceti dirigenti, o comunque eminenti, della Serenissima in Età moderna» (p. 7). Dopo una breve introduzione a cura di Giuseppe Gullino, apre le danze un frizzante intervento di Gino Benzoni («Le accademie e il tabù della politica»), il quale miscela il discorso storico propriamente detto sulle accademie in territorio veneto con i propri ricordi personali di acca...

  18. Propos autour d’un inventaire : quelques peintures italiennes à Bastia

    OpenAIRE

    Michel-Edouard Nigaglioni; Pierre Curie

    2005-01-01

    Du Moyen Age à la fin du XVIIIe siècle, Bastia fut une ville italienne dépendant de la république de Gênes. C’est pourquoi les églises de la ville conservent encore nombre de toiles d’artistes génois (Ottavio Cambiaso, Domenico Piola, Giuseppe Badaracco) ou provenant de régions italiennes proches de la Corse (Giovanni Bilivert). En 1844, le legs du cardinal Fesch, oncle de Napoléon, fait entrer dans les collections municipales une centaine de tableaux italiens. Des restaurations récentes (Lav...

  19. History of the early dipteran systematics in Italy: from Lyncei to Battista Grassi.

    Science.gov (United States)

    Baccetti, B

    2008-12-01

    This presentation starts with Galileo's discovery of the microscope and the first Lyncei. Giovanni Heckius and Francesco Stelluti demonstrated different kinds of mosquitoes. Later, in Florence, the Academy of Cimento solved the problem of mosquito reproduction with the discoveries of Francesco Redi, Pietro Paolo da Sangallo, Giuseppe Del Papa and Giovanni Maria Lancisi in the 18th century. In 19th century Eugenio Ficalbi reviewed the Italian Culicids. Once Battista Grassi solved the cycle of Anopheles and Plasmodia, further researches followed by Golgi, Celli, Marchiafava, Bastianelli and Bignami, as well as by Roland Ross.

  20. CERN Scuba Diving Club

    CERN Multimedia

    Club Subaquatique du CERN

    2017-01-01

    Interested in scuba diving? Fancy a fun trial dive? Like every year, the CERN Scuba Diving Club is organizing two free trial dive sessions. Where? Varembé Swimming Pool, Avenue Giuseppe Motta 46, 1202 Genève When? 25th October and 1st November at 19:15 (one session per participant) Price? Trial dives are FREE! Swimming pool entrance 5,40 CHF. What to bring? Swimwear, towel, shower necessities and a padlock – diving equipment will be provided by the CSC. For more information and to subscribe, follow the link below: http://cern.ch/csc-baptemes-2017 Looking forward to meeting you!

  1. Il melodramma e i suoi libretti: un educatore dell’immaginario tra borghesia e popolo (parte prima

    Directory of Open Access Journals (Sweden)

    Franco Cambi

    2011-11-01

    Full Text Available In the last two decades and beyond is robustly developed a line of investigation and critical-literary-musical theater around the opera librettos. A field that is growing and going through specialized education or more minute explorations, including pedagogical and educational reflection. Even today we discuss a lot about the identity of opera librettos, and the author has touched on some innovative aspects that emerged during the Romanticism, such as, for example, civil, political and ideological issues (themes still very present. He deals with major authors, such as Giuseppe Verdi, stressing the educational, political and cultural value of their works and textbooks on.

  2. I margini ruvidi della città in estensione. Tra Palermo e Partinico, ipotesi alternative / The rough edges of the "expanding town". Projects between Palermo and Partinico

    Directory of Open Access Journals (Sweden)

    Andrea Sciascia

    2013-07-01

    Full Text Available La ricerca dell’Unità di Palermo, di cui è responsabile il Prof. Andrea Sciascia, si è interessata a quel territorio, ad ovest di Palermo, incluso fra Isola delle Femmine e Partinico. In questo ambito esercitano una speciale azione attrattiva e contrapposta Palermo e l’aeroporto Falcone e Borsellino. L’effetto di tale azione si registra su quelle aree “verdi”, agricole o residuali, che costituiscono spesso i margini fra i nuclei densi inclusi nel territorio di studio (Isola delle Femmine, Capaci, Carini, Cinisi, Terrasini e Partinico. Alla luce del testo La città in estensione di Giuseppe Samonà, su alcune di queste aree di margine, opportunamente selezionate, sono state raccolte alcune ipotesi di progetto che prefigurano una possibile alternativa alla campagna urbanizzata. / Research Unit of Palermo, where Prof. Andrea Sciascia is responsible, focused on the territory west of Palermo between Isola delle Femmine and Partinico. In this context, Palermo and Falcone-Borsellino Airport exert a special and contrasted action. This effect manifests itself on "green" agricultural or residual areas, which are often the margins between the dense cores included in the study area (Isola delle Femmine, Capaci, Carini, Cinisi Terrasini and Partinico. According to the text by Giuseppe Samona about the Expanding Town, some of these fringe areas, appropriately selected, have been redesigned to envisage a possible alternative to the urbanized countryside.

  3. Glossario per la città europea / Glossary for the European city

    Directory of Open Access Journals (Sweden)

    Yannis Tsiomis

    2014-09-01

    Full Text Available Il concetto di “città in estensione” di Giuseppe Samonà è l'occasione per riflettere sul significato del fenomeno urbano oggi. L’autore lo fa attraverso nove punti, da “estensione” a “polisemia”, passando per “scala”, “metodo” e “funzione”, che diventano i termini di un nuovo glossario ragionato per la città europea, per un approccio cosciente allo studio e al progetto di quello che lui chiama “il dilemma territoriale”. / Giuseppe Samonà's idea of the "city in extension" offers the occasion to reflect on the meaning of the urban phenomenon today. The author does so through nine points, from “extension” to “polysemy”, passing via “scale”, “method” and “function”, which become the terms of a new reasoned glossary for the European city, for an aware approach to studio and the project of what he calls “the territorial dilemma”.

  4. Posttraumatic stress symptoms, dissociation, and alexithymia in an Italian sample of flood victims

    Directory of Open Access Journals (Sweden)

    Craparo G

    2014-11-01

    Full Text Available Giuseppe Craparo,1 Alessio Gori,2 Elvira Mazzola,1 Irene Petruccelli,1 Monica Pellerone,1 Giuseppe Rotondo3 1Faculty of Human and Social Sciences, Kore University of Enna, Enna, Italy; 2Department of Psychology, University of Florence, Florence, Italy; 3Department of Psychology, Unit of Psychotraumatology, San Raffaele Giglio Hospital of Cefalù, Cefalù, Italy Background: Several studies have demonstrated a significant association between dissociation and posttraumatic symptoms. A dissociative reaction during a traumatic event may seem to predict the later development of posttraumatic stress symptoms. Moreover, several researchers also observed an alexithymic condition in a variety of traumatized samples.Methods: A total of 287 flood victims (men =159, 55.4%; women =128, 44.6% with an age range of 17–21 years (mean =18.33; standard deviation =0.68 completed the following: Impact of Event Scale–Revised, Dissociative Experiences Scale II, Twenty-Item Toronto Alexithymia Scale, and Peritraumatic Dissociative Experiences Questionnaire.Results: We found significant correlations among all variables. Linear regression showed that peritraumatic dissociation plays a mediator role between alexithymia, dissociation, and posttraumatic stress symptoms.Conclusion: Our results seem to confirm the significant roles of both dissociation and alexithymia for the development of posttraumatic symptoms. Keywords: peritraumatic dissociation, posttraumatic symptoms, PTSD

  5. Peripheral artery disease: potential role of ACE-inhibitor therapy

    Directory of Open Access Journals (Sweden)

    Giuseppe Coppola

    2008-12-01

    Full Text Available Giuseppe Coppola, Giuseppe Romano, Egle Corrado, Rosa Maria Grisanti, Salvatore NovoDepartment of Internal Medicine, Cardiovascular and Nephro-Urological Diseases, Chair of Cardiovascular Disease, University of Palermo, Palermo, ItalyAbstract: Subjects with peripheral arterial disease (PAD of the lower limbs are at high risk for cardiovascular and cerebrovascular events and the prevalence of coronary artery disease in such patients is elevated. Recent studies have shown that regular use of cardiovascular medications, such as therapeutic and preventive agents for PAD patients, seems to be promising in reducing long-term mortality and morbidity. The angiotensin-converting-enzyme (ACE system plays an important role in the pathogenesis and progression of atherosclerosis, and ACE-inhibitors (ACE-I seem to have vasculoprotective and antiproliferative effects as well as a direct antiatherogenic effect. ACE-I also promote the degradation of bradykinin and the release of nitric oxide, a potent vasodilator; further, thay have shown important implications for vascular oxidative stress. Other studies have suggested that ACE-I may also improve endothelial dysfunction. ACE-I are useful for reducing the risk of cardiovascular events in clinical and subclinical PAD. Particularly, one agent of the class (ie, ramipril has shown in many studies to able to significantly reduce cardiovascular morbidity and mortality in patients with PAD.Keywords: atherosclerosis, peripheral arterial disease, endothelial dysfunction, ACE-inhibitors

  6. La mafia ai tempi di Expo

    Directory of Open Access Journals (Sweden)

    Il Comitato di esperti antimafia del Comune di Milano

    2016-11-01

    Full Text Available La sezione “Il documento” propone due capitoli della Relazione conclusiva redatta dal “Comitato di esperti per lo studio e la promozione di attività finalizzate al contrasto dei fenomeni di stampo mafioso e della criminalità organizzata sul territorio milanese, anche in vista della manifestazione Expo Milano 2015”, consegnata il 28 ottobre 2016 all’ex Sindaco di Milano Giuliano Pisapia e all’attuale Sindaco Giuseppe Sala. Gli estratti qui proposti riguardano le infiltrazioni mafiose in Expo e la presenza mafiosa a Milano.  Parole chiave: Comitato di esperti; Expo 2015; Milano; ‘ndrangheta; appalti The section ‘The Document” offers two chapters of the last report issued by the Antimafia Committee of the City Council of Milan (Comitato di esperti per lo studio e la promozione di attività finalizzate al contrasto dei fenomeni di stampo mafioso e della criminalità organizzata sul territorio milanese, anche in vista della manifestazione Expo Milano 2015, and presented on the 28th October 2016 to the former Mayor of Milan, Giuliano Pisapia, and to the actual Mayor Giuseppe Sala.  The excerpts here proposed regard the problems faced by the Committee in the years which have led up to Expo 2015 and the new scenarios of the presence of the Mafia in the area of Milan.  Keywords: Committee of experts; Expo 2015; Milan; ‘ndrangheta; public procurements

  7. Silvano Arieti's novel The Parnas: a scene from the Holocaust.

    Science.gov (United States)

    Meghnagi, David

    2014-12-01

    Silvano Arieti was an Italian psychoanalyst who undertook psychoanalysis of schizophrenic patients in the 1960s and 1970s. He left Italy in 1939 at the age of twenty-four following the Race Laws of 1938, and moved to New York until his death in 1981. A training analyst and author of several psychoanalytic and academic books, Arieti kept his research open in a wide variety of directions, giving equal weight to the internal world--as it seen from the psychoanalytic viewpoint--and to the organic functioning of the brain, as viewed from the perspective of the neurosciences. Arieti's interpretation of schizophrenia helped to overcome the dichotomies between the classical psychoanalytic approach, neurobiological research, and research into cognition, and opened up new paths for an interdisciplinary understanding of mental functioning and creative processes. This paper examines Arieti's book The Parnas (1979); this is a partly-fictionalised account of a pre-eminent figure (Parnas in Hebrew means "head") in the Jewish community in Pisa, Giuseppe Pardo Roques, in the 1930s and early 1940s, who experienced mental illness and was killed in the Nazi extermination of Jews. The paper examines Arieti?s reflections on what he sees as the 'insights' provided by mental illness, which are considered through the figure of Giuseppe Pardo Roques, and in the context of the trauma of the Shoah in Italy. Copyright © 2014 Institute of Psychoanalysis.

  8. Enlightening music: the catalogue and digitisation project of Verdi’s archive at the “Archivio Storico Ricordi” in Milan

    Directory of Open Access Journals (Sweden)

    Mathias Balbi

    2014-05-01

    Full Text Available Our contribution concentrates on the processes of cataloguing and digitising of hand–written letters and business documents belonging to the ''Ricordi Historical Archive'' in Milan, which is at present housed in the Braidense National Library; the archive possesses documents referring to the history of the publishing company covering the two centuries of its activities. Starting from the ledgers compiled by Giovanni Ricordi, which cover a period from 1814 up to the middle of the 19th century to the documents relative to the school of engraving, the archive also houses a large number of editorial catalogues, published by Ricordi and by other publishing houses which it took over, as well as the original contracts stipulated with composers and librettists from Giuseppe Verdi and Giacomo Puccini to Arrigo Boito. The collection of about 15,000 hand–written letters covers the period from the beginning of the 19th century to the end of the 20th century and includes documents sent to Ricordi from writers, singers authors, and composers such as Giuseppe Verdi, Giacomo Puccini and Ottorino Respighi and librettists Luigi Illica, Giuseppe Giacosa and Arrigo Boito. The second part of the correspondence is made up letter–books and business correspondence which were kept intact from 1888 to 1962, except for the period from 1944 to 1953. Since 2006, work has been carried out to catalogue and digitise the Ricordi Archive based on the standards set out by the National Library Service (Servizio Bibliotecario Nazionale – SBN which is head of the Central Institute for the Single Catalogue (ICCU. The structure and use of the archive and the external transmission of its contents are safeguarded and enhanced thanks to the combined work of cataloguing and digitisation of this heritage: the preliminary cataloguing of the documents uses a simplified model of the scheme adopted in the description of the manuscript according to sw Manus, elaborated by ICCU: the

  9. Factors influencing choice of chemotherapy in metastatic colorectal cancer (mCRC

    Directory of Open Access Journals (Sweden)

    Rossi L

    2013-11-01

    Full Text Available Luigi Rossi, Foteini Vakiarou, Federica Zoratto, Loredana Bianchi, Anselmo Papa, Enrico Basso, Monica Verrico, Giuseppe Lo Russo, Salvatore Evangelista, Guilia Rinaldi, Francesca Perrone-Congedi, Gian Paolo Spinelli, Valeria Stati, Davide Caruso, Alessandra Prete, Silverio TomaoDepartment of Medico-Surgical Sciences and Biotechnologies, "Sapienza" University of Rome, Rome, Italy; Oncology Unit, ICOT, Latina, ItalyAbstract: Management of metastatic colorectal cancer requires a multimodal approach and must be performed by an experienced, multidisciplinary expert team. The optimal choice of the individual treatment modality, according to disease localization and extent, tumor biology, and patient clinical characteristics, will be one that can maintain quality of life and long-term survival, and even cure selected patients. This review is an overview of the different therapeutic approaches available in metastatic colorectal cancer, for the purpose of defining personalized therapeutic algorithms according to tumor biology and patient clinical features.Keywords: metastatic colorectal cancer, patient clinical features, tumor biology, multidisciplinary approach

  10. Toward a formal ontology for narrative

    Directory of Open Access Journals (Sweden)

    Ciotti, Fabio

    2016-03-01

    Full Text Available In this paper the rationale and the first draft of a formal ontology for modeling narrative texts are presented. Building on the semiotic and structuralist narratology, and on the work carried out in the late 1980s by Giuseppe Gigliozzi in Italy, the focus of my research are the concepts of character and of narrative world/space. This formal model is expressed in the OWL 2 ontology language. The main reason to adopt a formal modeling approach is that I consider the purely probabilistic-quantitative methods (now widespread in digital literary studies inadequate. An ontology, on one hand provides a tool for the analysis of strictly literary texts. On the other hand (though beyond the scope of the present work, its formalization can also represent a significant contribution towards grounding the application of storytelling methods outside of scholarly contexts.

  11. Note e Recensioni

    Directory of Open Access Journals (Sweden)

    a cura di Mariagrazia Portera

    2013-12-01

    Full Text Available Volumi Winfried Menninghaus, La promessa della bellezza, [Fabrizio Desideri, p. 272] • David Rothenberg, Survival of the Beautiful. Art, Science and Evolution [Danae Crocchiola, p. 274] • Lev Manovich, Software Takes Command [Angela Maiello, p. 277]. Note Method in Aesthetics: Philosophy, Evolution and the Cognitive Sciences [Aaron Meskin, Matthew Kieran, Gregory Currie, p. 280] • L’Abitare possibile. Estetica, Architettura e New Media, Ravello, Auditorium Oscar Niemeyer, 28-30 maggio 2013 [Sara Matetich, p. 282] • Copenhagen Summer School in Phenomenology and Philosophy of Mind, University of Copenhagen, 12-16 Agosto 2013 [Raoul Frauenfelder, p. 289] • Ciò che è vivo e ciò che è morto nell’estetica di Archibald Ali- son. Nota a margine del convegno: Neoestetica ed emozione. Archibald Alison e l’estetica con- temporanea, Palermo, 4-5 ottobre 2013 [Giuseppe Pucci, p. 294

  12. Ungaretti tradutor discreto e a analogia entre os poetas árcades Tomás Antônio Gonzaga e Giovanni Meli

    Directory of Open Access Journals (Sweden)

    Lucia Wataghin

    2003-07-01

    Full Text Available Será apresentada e discutida a interessante analogia, sugerida por Giuseppe Ungaretti, entre a poesia de T.A. Gonzaga e a poesia em dialeto siciliano de um outro árcade, Giovanni Meli, seu contemporâneo. Em seguida, a partir das traduções realizadas por G. Ungaretti (1946. G. Vegezzi-Ruscalla (1844, E. de Monglave e P. Chalas (1825 da lira Tu não verás, Marília..., de T.A. Gonzaga, serão comentados aspectos do poema e de sua recepção em épocas e países diferentes.

  13. Scuba club

    CERN Document Server

    Scuba club

    2015-01-01

    The CERN Scuba club will be offering a free trail scuba dive sessions for anyone interested in trying this passionate activity. You don't have to be a daredevil or a great swimmer. Anyone curious to try can have a go. So don't miss the golden opportunity to discover a whole new fascinating world, taking your first breaths underwater! Two separate sessions will be help on Wednesday 7th October and Wednesday 14th October, both starting at 19:00 at the Varembe Swimming pool, 46 Avenue Giuseppe-Motta, 1202 Geneva. To sign up send an email to: subaqua@cern.ch (please indicate which date you wish to attend. You may only attend one). This event is open to adults and young people 14+. Minors must be accompanied by a parent. More information will soon be made available at the club website https://subaqua.web.cern.ch/subaqua/

  14. LA GEOMETRIA NON-ARCHIMEDEA. DALLE PREMESSE AGLI INFINITI MODELLI ATTUALI

    Directory of Open Access Journals (Sweden)

    R. Mascella

    2006-02-01

    Full Text Available La geometria non-archimedea sembra essere un’ipotesi astratta e fantasiosa, accettabile nella matematica ma non per la rappresentazione spaziale, perché usa concetti a lungo esplorati nel pensiero scientifico e filosofico e spesso rigettati, quali l’infinito e l’infinitesimo attuali. L’articolo analizza gli aspetti storici, epistemologici, filosofici e matematici legati a questa geometria ed alle sue radici, considerando l’impostazione dell’inventore Giuseppe Veronese, della formalizzazione analitica di Levi-Civita e di altri matematici e filosofici che sul tema hanno fornito risultati e dibattuto, quali Cantor, Hilbert e Hahn, per terminare con gli infiniti modelli che oggi conosciamo. Questa geometria appare sottovalutata, ma si presta ad un ruolo non meno importante di alcune alternative non-euclidee, spesso semplicisticamente considerate come uniche varianti astratte dei modelli euclideo e riemanniano.

  15. Criações e releituras de imagens–uma pesquisa no ensino de artes visuais

    Directory of Open Access Journals (Sweden)

    Maristani Polidori Zamperetti

    2013-01-01

    Full Text Available The paintings of Giuseppe Archimboldo ( 1527 - 1593 populate the imagina - tions of children and adults of all times, allowing the distance from the look of your images, the visualization of new figures, generating curiosity, or even strange. I tried to understand the relationships established between youth identities and their creative expressions – portraits and self portraits – artistic embodied in three-dimensional struc - tures, which served as sources of research on teaching. Drew up a proposal for readings and compositions plastic three-dimensional elements of nature or industrially produced, selected and collected by the students of basic education in the subject of visual arts, a municipal school in Rio Grande do Sul, in 2007 . Producing pictures full of visual sen - sory appeals to the touch and smell, students recreating elements of everyday life curious figures, exotic and inquisitive, which express their identity forms.

  16. Women taking the “blue pill” (sildenafil citrate: such a big deal?

    Directory of Open Access Journals (Sweden)

    Lo Monte G

    2014-11-01

    Full Text Available Giuseppe Lo Monte, Angela Graziano, Isabella Piva, Roberto Marci Department of Morphology, Surgery, and Experimental Medicine, University of Ferrara, Ferrara, Italy Abstract: For years, phosphodiesterase type 5 inhibitors have been used for the treatment of erectile dysfunctions. Due to the similarities between male and female sexual response, several studies have assessed the effects of sildenafil citrate (Viagra® in women affected by female sexual arousal disorder. The results are still conflicting and the drug is not devoid of adverse effects. Furthermore, female sexual arousal disorder is a heterogeneous condition whose underlying causes are difficult to diagnose and appropriate treatment requires a thorough sexual, psychological, and medical history along with specialist consultations. The clinician should pursue a global approach to the patient with sexual difficulties, while non-hormonal treatment such as phosphodiesterase type 5 inhibitors (ie, sildenafil citrate should be kept as the last option. Keywords: phosphodiesterase type 5 inhibitors, female sexual arousal disorder (FSAD, sildenafil citrate

  17. The genetics of Ménière’s disease

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    Chiarella G

    2015-01-01

    Full Text Available Giuseppe Chiarella,1 C Petrolo,1 E Cassandro2 1Department of Experimental and Clinical Medicine, Audiology and Phoniatrics Unit, Magna Graecia University of Catanzaro, Catanzaro, Italy; 2Department of Medicine and Surgery, University of Salerno, Salerno, Italy Abstract: Our understanding of the genetic basis of Ménière’s disease (MD is still limited. Although the familial clustering and the geographical and racial differences in incidence strongly suggest a certain role for genetic factors in the development of MD, no convincing evidence for an association with any gene exists, at present. In this review, starting from rational bases for a genetic approach to MD, we explored the numerous reports published in literature and summarize the recent advances in understanding of the genetic fundaments of the disease. Keywords: Mènière’s disease, gene, vertigo, etiology, pathogenesis

  18. Université de Genève | Séminaire de physique corpusculaire | 15 May

    CERN Multimedia

    2013-01-01

    Thorium or Uranium fuel cycle for advanced nuclear reactors ? Fuel recycling, multi-recycling, breeding and burning, Dr Jiri Krepel, Paul Scherrer Institut (PSI).   Wednesday 15 May, 11:15 a.m. Science III, Auditoire 1S081 30, quai Ernest-Ansermet, 1211 Genève 4 Abstract: The Thorium fuel cycle provides several advantages, which make it very attractive; e.g. lower waste production and possibly improved reactor safety. However, there are also some drawbacks if compared with the Uranium cycle. The seminar will provide an overview of the basic physical features of both the Thorium and the Uranium fuel cycles and comparison of their performance (criticality, breeding gain) and safety-related parameters (Doppler effect, coolant density effect), with respect to fuel recycling, multi-recycling, breeding and burning. Organised by Prof. Teresa.Montaruli@unige.ch and Prof. Giuseppe.Iacobucci@unige.ch. More information here.

  19. The film adaptation of an american tragedy and Othello in match point

    Directory of Open Access Journals (Sweden)

    Ana Paula Bianconcini Anjos

    2017-01-01

    Full Text Available http://dx.doi.org/10.5007/2175-8026.2017v70n1p161 The aim of the present article is to recover the history of the cinematic adaptations of the novel An American Tragedy (1925, by Theodore Dreiser, reinstating the discussions of the drowning scene. Sergei Eisenstein’s writings on the possibilities of the use of the interior monologue in films and Bertolt Brecht’s remarks on the role of the soundtrack in Dreiser’s novel adaptation offer an important entry into the analysis of the film Match Point (2005, by Woody Allen. In Match Point, the use of the soundtrack, in particular the collage with the opera Othello (1887, by Giuseppe Verdi, instigates the spectator to reflect on the narrative possibilities of film adaptation.

  20. Université de Genève | Séminaire de physique corpusculaire | 6 November

    CERN Multimedia

    2013-01-01

    Particle sensors in CMOS Technologies, Dr Ivan Peric, Heidelberg University.   Wednesday 6 November 2013, 11:15 a.m. Science III, Auditoire 1S081 Boulevard d’Yvoy, 1211 Genève 4 Abstract: The use of pixel sensors implemented in standard CMOS technologies has gained in popularity over the last decade. The most prominent application is consumer electronics – the sensors for digital cameras. CMOS sensors are also a promising option for high energy physics. An overview of existing CMOS detector structures for particle tracking will be given, and their properties compared. Organised by Prof. Teresa.Montaruli@unige.ch and Prof. Giuseppe.Iacobucci@unige.ch. More information here.

  1. Patologie sociali, resistenze e difese degli insegnanti nell’istituzione scolastica: Considerazioni cliniche e pedagogiche

    Directory of Open Access Journals (Sweden)

    Tommaso Fratini

    2014-12-01

    Full Text Available L’articolo prende in esame il tema di alcune resistenze e difese degli insegnanti all’interno dell’istituzione scolastica. Partendo dall’attuale condizione di emergenza della scuola italiana e rifacendosi al concetto di patologia sociale di Giuseppe Di Chiara, viene argomentato come tali resistenze coprano le angosce persecutorie degli insegnanti nel loro lavoro scolastico quotidiano nel rapporto con gli allievi. L’articolo, tra le varie forme di patologia istituzionale, affronta principalmente il tema di quelle che presiedono alle resistenze degli insegnanti al lavoro introspettivo con il proprio mondo interno, conseguenza e ulteriore cagione di sensi di colpa nel rapporto con gli allievi e di fenomeni di burnout lavorativo degli stessi insegnanti. Tali fenomeni vanno nella direzione del rinforzo sia di un atteggiamento di chiusura verso la collaborazione con professionisti esterni all’istituzione scolastica, sia di un atteggiamento di minore empatia e vicinanza emotiva con la realtà interna degli allievi.

  2. Don Carlos: Variations of Tragic from Schiller to Verdi

    Directory of Open Access Journals (Sweden)

    Fabio Vittorini

    2017-11-01

    Full Text Available In 1867 Giuseppe Verdi makes a grand opéra out of the dramatic poem Don Carlos, Infant von Spanien (1787 by Friedrich von Schiller. The workshop of Don Carlos lasts twenty years, from 1866 to 1886, when Verdi (reopens and closes several other workshops (Simon Boccanegra, La forza del destino, Aida, Requiem, Otello, creating a porous work in progress, whose analysis keeps giving us surprises. The libretto by Joseph Méry et Camille Du Locle, under the supervision of the composer, is a palimpsest where, under the official text referable to the common historical nucleus and its best known literary versions, some hidden or deleted heterogeneous texts appear, in a supranational, multilinguistic, intercultural and intertextual dimension, not always stirring along the road of a locatable derivation, of a voluntary imitation, but sometimes taking the shape of an unpredictable dissemination.

  3. (Almost anonymous: collaborators of Samuel das Neves technical office in the early 1910s

    Directory of Open Access Journals (Sweden)

    Ana Paula Nascimento

    2018-04-01

    Full Text Available The presence of collaborators in engineering and architecture offices is an insufficiently researched subject, most of which remain unknown even in specialized publications. This paper analyzes the participation of some professionals in Samuel das Neves Technical Office (Escritório Técnico Samuel das Neves during the first two decades of the 20th century, especially about works related to the State Penitentiary Competition (Concurso da Penitenciária do Estado and to São Paulo’s Master Plan (Plano Melhoramentos. Most of them were foreigners with extensive professional knowledge and who worked at the São Paulo headquarters of the company in its best known and commented period: Carlos Escobar, Giulio Micheli, Giuseppe Sacchetti, A. Maurice de Ladrière, José Talarico, and Giácomo Corberi.

  4. Kinomic and phospho-proteomic analysis of breast cancer stem-like cells

    DEFF Research Database (Denmark)

    Leth-Larsen, Rikke; Christensen, Anne Geske Lindhard; Ehmsen, Sidse

    Kinomic and phospho-proteomic analysis of breast cancer stem-like cells Rikke Leth-Larsen1, Anne G Christensen1, Sidse Ehmsen1, Mark Møller1, Giuseppe Palmisano2, Martin R Larsen2, Henrik J Ditzel1,3 1Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark 2Institute...... of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark 3Dept. of Oncology, Odense University Hospital, Odense, Denmark Cancer stem cells are thought to be responsible for tumorigenic potential and to possess resistance mechanisms against chemotherapy- and radiation-induced cancer...... cell death, while the bulk of a tumor lacks these capacities. The resistance mechanisms may cause these cells to survive and become the source of later tumor recurrence, highlighting the need for therapeutic strategies that specifically target pathways central to these cancer stem cells. The CD44hi...

  5. Scuba club

    CERN Multimedia

    Scuba club

    2014-01-01

    The CERN Scuba club will be offering a free trail scuba dive sessions for anyone interested in trying this passionate activity. You don't have to be a daredevil or a great swimmer. Anyone curious to try can have a go. So don't miss the golden opportunity to discover a whole new fascinating world, taking your first breaths underwater! Two separate sessions will be help on Wednesday 24th September and Wednesday 1st October, both starting at 19:00 at the Varembe Swimming pool, 46 Avenue Giuseppe-Motta, 1202 Geneva. To sign up send an email to: subaqua@cern.ch (please indicate which date you wish to attend. You may only attend one). This event is open to adults and young people 14+. Minors must be accompanied by a parent. More information will soon be made available at the club website https://subaqua.web.cern.ch/subaqua/.

  6. Professor Camillo Negro's Neuropathological Films.

    Science.gov (United States)

    Chiò, Adriano; Gianetto, Claudia; Dagna, Stella

    2016-01-01

    Camillo Negro, Professor in Neurology at the University of Torino, was a pioneer of scientific film. From 1906 to 1908, with the help of his assistant Giuseppe Roasenda and in collaboration with Roberto Omegna, one of the most experienced cinematographers in Italy, he filmed some of his patients for scientific and educational purposes. During the war years, he continued his scientific film project at the Military Hospital in Torino, filming shell-shocked soldiers. In autumn 2011, the Museo Nazionale del Cinema, in partnership with the Faculty of Neurosciences of the University of Torino, presented a new critical edition of the neuropathological films directed by Negro. The Museum's collection also includes 16 mm footage probably filmed in 1930 by Doctor Fedele Negro, Camillo's son. One of these films is devoted to celebrating the effects of the so-called "Bulgarian cure" on Parkinson's disease.

  7. Cinema on Cinema: The Kinship between Cinema Paradiso and Zıkkımın Kökü, Karpuz Kabuğundan Gemiler Yapmak, Sinema Bir Mucizedir

    Directory of Open Access Journals (Sweden)

    Basak Demiray

    2011-08-01

    Full Text Available This study consists of a comparative analysis of four films which fall under the category of “cinema on cinema”. These films are Cinema Paradiso (Giuseppe Tornatore, 1988, Italy, Zıkkımın Kökü (Memduh Ün, 1993, Turkey, Karpuz Kabuğundan Gemiler Yapmak/ Boats out of Watermelon Rinds ( Ahmet Uluçay, 2004, Turkey, Sinema Bir Mucizedir/ Cinema is a Miracle (Memduh Ün- Tunç Başaran, 2005, Turkey. It will be argued that these films have four main points of similarity. First, they are the instances of “cinema on cinema”; second, they are biographical films; third, their plots are constructed upon the rural lives of the past; fourth, they are about cinephilia.

  8. Intercultural Dialogue and Ethical Challenge in the Latin-American Thought

    Directory of Open Access Journals (Sweden)

    Victor Martin Fiorino

    2016-12-01

    Full Text Available The article analyzes some central problems of the intercultural dialogue in the context of philosophical, historiographical and political debates promoted by the contemporary LatinAmerican thought. The analysis concerns: the anthropological and ethical approach of interculturalityby Arturo Andrés Roig, its relation with the literary avant-gardes in Latin Americaand its expression in a liberationist philosophy oriented to overcome the patriarchalism; the interculturality as a space for the asking by the other and as intelligence to live together,as well as its educational consequences, with regard to a pedagogy and to an ethics of decolonization; the relation between interculturality and integration of peoples, on the basis of the proposal of Giuseppe Cacciatore about the ethics of imagination.

  9. Digital resources

    Directory of Open Access Journals (Sweden)

    Redazione Reti Medievali (a cura di

    2005-12-01

    Full Text Available Bibliotheca Latinitatis Mediaevalis (circa VII sec. - XIV sec. IntraText Digital Library [01/06] Corpus Scriptorum Latinorum. A digital library of Latin literature by David Camden [01/06] Fonti disponibili online concernenti la vita religiosa medievale Rete Vitae Religiosae Mediaevalis Studia Conectens [01/06] Fuentes del Medievo Hispanico Instituto de Historia, Consejo Superior de Investigaciones Científicas [01/06] Latin Literature Forum Romanum [01/06] Ludovico Antonio Muratori, Dissertazioni sopra le antichità italiane, 1751 Biblioteca dei Classici Italiani di Giuseppe Bonghi [01/06] Medieval Latin The Latin Library [01/06] Médiévales Presses Universitaires de Vincennes - Revues.org [01/06] Regesta imperii Deutsche Kommission für die Bearbeitung der Regesta Imperii e.V. [01/06] Suda On Line Byzantine Lexicography [01/06

  10. The harmonious relationship between faith and science from the perspective of some great saints: A brief comment.

    Science.gov (United States)

    Cortés, Manuel E; Del Río, Juan Pablo; Vigil, Pilar

    2015-02-01

    The objective of this editorial is to show that a harmonious relationship between science and faith is possible, as exemplified by great saints of the Catholic Church. It begins with the definitions of science and faith, followed by an explanation of the apparent conflict between them. A few saints that constitute an example that a fruitful relationship between these two seemingly opposed realities has been possible are Saint Albert the Great, Saint John of the Cross, Saint Giuseppe Moscati, and Saint Edith Stein, among others, and this editorial highlights their deep contributions to the dialogue between faith and reason. This editorial ends with a brief discussion on whether it is possible to be both a scientist and a man of faith.

  11. In memory of a Maestro

    Directory of Open Access Journals (Sweden)

    Luigi Bodria

    2013-03-01

    Full Text Available Seldom the qualification of Maestro may find more appropriate use that in the case of Giuseppe Pellizzi, Emeritus Professor at the University of Milano, died suddenly last summer. His contribution of enthusiasm and intelligence, his strong personality and commitment has deeply influenced at national and international level the agricultural engineering community and is death has left a gap that cannot be filled in all whose who have had the chance and the privilege of working alongside. Thanks to his uncommon ability to attract and motivate young people, fascinating them with his intellectual dynamism and making them feel important and vital part of the Institute and its projects, he was a master of great charisma who led the training and scientific growth of numerous young researchers...

  12. Highlights from e-EPS: the 2015 EPS High Energy Physics Prize winners

    CERN Multimedia

    Thomas Lohse, e-EPS News

    2015-01-01

    The EPS High Energy Physics Division announces the winners of its 2015 prizes, which will be awarded at the Europhysics Conference on High-Energy Physics (EPS-HEP 2015), Vienna (Austria) 22−29 July. Many people from CERN were among the winners.   The 2015 High Energy and Particle Physics Prize, for an outstanding contribution to High Energy Physics, is awarded to James D. Bjorken “for his prediction of scaling behaviour in the structure of the proton that led to a new understanding of the b interaction”, and to Guido Altarelli, Yuri L. Dokshitzer, Lev Lipatov, and Giorgio Parisi “for developing a probabilistic field theory framework for the dynamics of quarks and gluons, enabling a quantitative understanding of high-energy collisions involving hadrons”. The 2015 Giuseppe and Vanna Cocconi Prize, for an outstanding contribution to Particle Astrophysics and Cosmology in the past 15 years, is awarded to Francis Halzen “for his visiona...

  13. Methods and approaches to provide feedback from nuclear and covariance data adjustment for improvement of nuclear data files. SG39 meeting, December 2016

    International Nuclear Information System (INIS)

    Cabellos, Oscar; ); PELLONI, Sandro; Ivanov, Evgeny; Sobes, Vladimir; Fukushima, M.; Yokoyama, Kenji; Palmiotti, Giuseppe; Kodeli, Ivo

    2016-12-01

    The aim of WPEC subgroup 39 'Methods and approaches to provide feedback from nuclear and covariance data adjustment for improvement of nuclear data files' is to provide criteria and practical approaches to use effectively the results of sensitivity analyses and cross section adjustments for feedback to evaluators and differential measurement experimentalists in order to improve the knowledge of neutron cross sections, uncertainties, and correlations to be used in a wide range of applications. This document is the proceedings of the eighth Subgroup 39 meeting, held at the OECD NEA, Boulogne-Billancourt, France, on 1-2 December 2016. It comprises all the available presentations (slides) given by the participants: A - Presentations: Welcome and actions review (Oscar CABELLOS); B - Methods: - Detailed comparison of Progressive Incremental Adjustment (PIA) sequence results involving adjustments of spectral indices and coolant density effects on the basis of the SG33 benchmark (Sandro PELLONI); - ND assessment alternatives: Validation matrix vs XS adjustment (Evgeny IVANOV); - Implementation of Resonance Parameter Sensitivity Coefficients Calculation in CE TSUNAMI-3D (Vladimir SOBES); C - Experiment analysis, sensitivity calculations and benchmarks: - Benchmark tests of ENDF/B-VIII.0 beta 1 using sodium void reactivity worth of FCA-XXVII-1 assembly (M. FUKUSHIMA, Kenji YOKOYAMA); D - Adjustments: - Cross-section adjustment based on JENDL-4.0 using new experiments on the basis of the SG33 benchmark (Kenji YOKOYAMA); - Comparison of adjustment trends with the Cielo evaluation (Sandro PELLONI); - Expanded adjustment in support of CIELO initiative (Giuseppe PALMIOTTI); - First preliminary results of the adjustment exercise using ASPIS Fe88 and SNEAK-7A/7B k_e_f_f and b_e_f_f benchmarks (Ivo KODELI); E - Future actions, deliverables: - Discussion on future of SG39 and possible new subgroup (Giuseppe PALMIOTTI); - WPEC sub-group proposal: Investigation of Covariance Data in

  14. Antonio Mollari fra Canova e Valadier / Antonio Mollari between Canova and Valadier

    Directory of Open Access Journals (Sweden)

    Elisa Debenedetti

    2014-04-01

    Full Text Available Non è difficile inserire Antonio Mollari in un contesto europeo. Ad Antonio Canova lo lega una prima, importantissima lettera del 4 maggio 1807 nella quale, in seguito ad un invito trasmessogli dallo scultore, ma di cui è responsabile Filippo III Colonna, enumera tutte le sue opere; la seconda risale al 25 febbraio 1809. Dalla prima missiva si riescono a stabilire numerosi contatti con Giuseppe Valadier: a Corridonia (Collegiata dei Santi Pietro, Paolo e Donato; Ospedale e Chiesa di San Salvatore e a Macerata (Palazzo Conti già Ugolini. Tanto da giungere a considerare Mollari come il continuatore del Valadier nei cantieri marchigiani, dove la presenza del Maestro si manifesta come una sovrapposizione di motivi francesizzanti a soluzioni palladiane: componenti entrambe presenti nel Palazzo Tomassini a Corridonia, ricondotto al Maceratese. Fra l’altro le pagine di due Taccuini valadieriani, certo a lui note, si possono considerare a metà strada fra l’esercizio tipologico ed il modello. It’s not difficult to insert Antonio Mollari into a European context. A first very important letter, dated May 4th 1807, links him to Antonio Canova whereby, after inviting him, by wish of Phillip Colonna III , he then makes a list of all his works of art; the second is dated February 25th 1809. Various contacts with Giuseppe Valadier can be established from the first letter: in Corridonia (Saints Peter, Paul and Donato Collegiate church; St. Saviour’s Hospital and Church and in Macerata (Conti Palace ex Ugolini. So much so as to regard Mollari as Valadier’s continuator in the Marche construction sites, where the Maestro’s presence is expressed like a superimposition of Frenchified motives for Palladian solutions: both components being present in the Tomassini Palace in Corridonia, which can be traced back to Mollari. Moreover the pages of two Valdier Notebooks, which he must have known about, can be considered half way between a typological exercise

  15. Single nucleotide polymorphisms and unacceptable late toxicity in breast cancer adjuvant radiotherapy: a case report

    Directory of Open Access Journals (Sweden)

    Lazzari G

    2017-05-01

    Full Text Available Grazia Lazzari,1 Maria Iole Natalicchio,2 Angela Terlizzi,3 Francesco Perri,4 Giovanni Silvano1 1Radiation Oncology Unit, San Giuseppe Moscati Hospital, Taranto, 2Molecular Biology Laboratory, Pathological Anatomy Department, Ospedali Riuniti, Foggia, 3Medical Physic Unit, San Giuseppe Moscati Hospital, 4Medical Oncology Unit, Presidio Ospedaliero Centrale - Santissima Annunziata, Taranto, Italy Background: There has recently been a strong interest in the inter-individual variation in normal tissue and tumor response to radiotherapy (RT, because tissue radiosensitivity seems to be under genetic control. Evidence is accumulating on the role of polymorphic genetic variants, such as single nucleotide polymorphisms (SNPs that could influence normal tissue response after radiation. The most studied SNPs include those in genes involved in DNA repair (single- and double-strand breaks, and base excision and those active in the response to oxidative stress.Case report: We present the case report of a 60-year-old woman with early breast cancer who underwent adjuvant hormone therapy and conventional radiotherapy, and subsequently developed unacceptable cosmetic toxicities of the irradiated breast requiring a genetic test of genes involved in DNA repair mechanisms. The patient was found to be heterozygous for G28152A (T/C and C18067T (A/G mutations in X-ray repair cross-complementing group 1 (XRCC1 and 3 (XRCC3, respectively, homozygous for A313G (G/G mutation in glutathione S transferase Pi 1 (GSTP1, and wild-type for A4541G (A/A in XRCC3 and G135C (G/G in RAD51 recombinase.Conclusion: The role of SNPs should be taken into account when a severe phenomenon appears in normal tissues after radiation treatment, because understanding the molecular basis of individual radiosensitivity may be useful for identifying moderately or extremely radiosensitive patients who may need tailored therapeutic strategies. Keywords: radiosensitivity, SNPs, fibrosis, DNA repair

  16. Maria Carolina and Marie Antoinette: Sisters and Queens in the mirror of Jacobin Public Opinion

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    Cinzia Recca

    2014-09-01

    Full Text Available Marie Antoinette of Franceand Maria Carolina of Naples, both consorts, contributed to a flourishing of matronage, reproducing conceptions of royal femininity that embraced both the private and public roles they were expected to fulfil. However, while the political role of the first Queen has been largely reconsidered, her sister Maria Carolina has not yet been adjudicated impartially. This is somewhat curious, because Maria Carolina inherited from her sister the same disregard towards the Revolution and this, as perceived by the Jacobins, was duly proposed in their acrimonious criticism of her political role. This paper aims to focus on this criticism, analysing how the charges against Maria Carolina in the post-French revolutionary period, were a political duplication of the Jacobin attacks on Marie Antoinette from 1791 onwards. From this point of view, the paper will focus on the portrait of Maria Carolina in 1793 revolutionary Parisby Giuseppe Gorani, an Italian Jacobin noble. His Mémoires Secrets – where Maria Carolina was represented as a wicked woman in the same terms previously employed to denounce her sister Marie Antoinette by the French Republicans – was well known across Italy. This subject dominated the main pamphlets and brochures published in Naples in 1799, during the brief duration of the Neapolitan Republic, because it legitimised the rebellion against the monarchy. After the fall of the Neapolitan Republic, the political attacks on Maria Carolina continued likewise in France, where many Neapolitan patriots were obliged to flee. Analysing  Giuseppe Gorani’s Mémoires we gather that the portrait of Marie Antoinette’s sister was painted according to the main stereotypes of  French revolutionary political culture.

  17. Depression, body mass index, and chronic obstructive pulmonary disease – a holistic approach

    Directory of Open Access Journals (Sweden)

    Catalfo G

    2016-02-01

    Full Text Available Giuseppe Catalfo,1 Luciana Crea,1 Tiziana Lo Castro,1 Francesca Magnano San Lio,1 Giuseppe Minutolo,1 Gherardo Siscaro,2 Noemi Vaccino,1 Nunzio Crimi,3 Eugenio Aguglia1 1Department of Psychiatry, Policlinico “G. Rodolico” University Hospital, University of Catania, Catania, Italy; 2Operative Unit Neurorehabilitation, IRCCS Fondazione Salvatore Maugeri, Sciacca, Italy; 3Department of Pneumology, Policlinico “G. Rodolico” University Hospital, University of Catania, Catania, Italy Background: Several clinical studies suggest common underlying pathogenetic mechanisms of COPD and depressive/anxiety disorders. We aim to evaluate psychopathological and physical effects of aerobic exercise, proposed in the context of pulmonary rehabilitation, in a sample of COPD patients, through the correlation of some psychopathological variables and physical/pneumological parameters. Methods: Fifty-two consecutive subjects were enrolled. At baseline, the sample was divided into two subgroups consisting of 38 depression-positive and 14 depression-negative subjects according to the Hamilton Depression Rating Scale (HAM-D. After the rehabilitation treatment, we compared psychometric and physical examinations between the two groups. Results: The differences after the rehabilitation program in all assessed parameters demonstrated a significant improvement in psychiatric and pneumological conditions. The reduction of BMI was significantly correlated with fat mass but only in the depression-positive patients. Conclusion: Our results suggest that pulmonary rehabilitation improves depressive and anxiety symptoms in COPD. This improvement is significantly related to the reduction of fat mass and BMI only in depressed COPD patients, in whom these parameters were related at baseline. These findings suggest that depressed COPD patients could benefit from a rehabilitation program in the context of a multidisciplinary approach. Keywords: COPD, depression, aerobic exercise

  18. Rivas y Verdi: Las trampas de la libertad en La fuerza del sino y La forza del destino

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    Egido, Aurora

    2012-06-01

    Full Text Available A comparative analysis between Duque de Rivas’Don Álvaro o la fuerza del sino and La forza del destino by Giuseppe Verdi shows, even in their very titles, the close relationship between Spain and Italy since the days of the Golden Age. Both works posit the old theological problem of compatibility between predestination and free will, while adding new social and political insights into social and racial differences and highlighting the narrowness of the code of honour. Otherwise, as far as the admixture of genres or the treatment of costumbrismo and nationalism are concerned, the difference between both works increases in the second version of Verdi´s opera, in which the alteration of the denouement wipes out the tragical dimension of the spanish play.Un análisis comparativo entre Don Álvaro o la fuerza del sino del duque de Rivas y La forza del destino de Giuseppe Verdi demuestra, ya desde sus títulos, un viaje de y vuelta entre España e Italia que tiene como fondo la literatura del Siglo de Oro. Ambas obras plantean el viejo problema entre providencia y libertad, añadiendo nuevos relieves sociales y políticos sobre las diferencias de clase y raza que ponen en evidencia las estrecheces del código del honor. Las diferencias entre ambas —más allá de la mezcla genérica, el tratamiento costumbrista y el nacionalismo— se acentúan en la segunda versión de la ópera verdiana, que, al cambiar el desenlace, destruyó el sentido trágico del drama español.

  19. Mundo Braz. El devenir-mundo de Brasil y el devenir-Brasil del mundo

    Directory of Open Access Journals (Sweden)

    Rodrigo Martínez Reinoso

    2015-02-01

    Full Text Available Reseña: Mundo Braz. El devenir-mundo de Brasil y el devenir-Brasil del mundo   MundoBraz. El devenir-mundo de Brasil y el devenir-Brasil del mundo es el título que lleva la obra del filósofo italiano radicado en Brasil Giuseppe Cocco. Fue publicada originalmente en portugués (Río de Janeiro, 2009 y editada en español por la Editorial Traficantes de Sueños tres años después (Madrid, 2012. Sus principales aportaciones se relacionan con el análisis político y social de nuestra realidad contemporánea bajo una línea de investigación neo-marxista que ha dado origen a dos emblemáticas publicaciones, las cuales son en rigor los antecedentes inmediatos del espíritu crítico, transdisciplinario y altermundista que caracteriza a MundoBraz. [1] Cocco, Giuseppe (2012: MundoBraz. El devenir-mundo de Brasil y el devenir-Brasil del mundo. Traficantes de Sueños, Madrid. Giuseppe Cocco se formó en Italia y Francia y fue activista político en los años 70 de Autonomía Obrera. Es Licenciado en Ciencias Políticas (Università degli Studi di Padova, 1981, Licenciado en Ciencias Políticas (Université de Paris VIII, 1984, Master of Science Technologie et Société (Conservatoire National des Arts et Métiers, 1988, MA en Historia Social (Universidad de París I (Panthéon-Sorbonne, 1986 y Doctor en Historia Social (Universidad Paris I Panthéon-Sorbonne, 1993. Ejerce como profesor de la Universidad Federal de Río de Janeiro y es editor de diversas revistas de perfil neomarxista y altermundista: Global Brasil, Common Place y Multitudes. Un modo de resumir el valor de esta bella y asombrosa obra quizás consista en decir que cumple a cabalidad con el sentido de lo que Deleuze y Guattari han denominado como una política menor. La cual, paradójicamente, si bien derriba una serie de dogmas del liberalismo y del marxismo, tal mirada no se queda en un diagnóstico fatídico y determinista (como sería el economicismo que acusa al neoliberalismo de

  20. The embalming, the scientific method and the paleopathology: the case of Gaetano Arrighi (1836).

    Science.gov (United States)

    Ciranni, Rosalba; Caramella, Davide; Nenci, Riccardo; Fornaciari, Gino

    2005-01-01

    Since the most ancient times the problem of the artificial preservation of dead bodies has been an important object of study. In ancient and classic times the reasons leading to this practice were essentially of a religious and esoteric type, but in the modern age, following the development of medical and biological studies, embalming has assumed a more practical trend which is both medicine and scientific. The discovery of blood circulation has marked the scientific method which, in its various forms, has circulated all over Europe bringing fame to eminent anatomists such as Federico Ruysch (1638-1731), William (1718-1783) and John Hunter (1728-1793), Jean Nicolas Gannal (1791-1852), Giuseppe Tranchina, Laskowky and Brosch, who affirmed the embalming by endoarterial injection of conservation fluids making evisceration useless and obsolete. The advent of formalin and the introduction of new surgical and autoptic methods have made this practice gradually fall into disuse. For this reason, the mummy found in Leghorn (Tuscany, Central Italy) is of particular importance since was obtained applying the intravascular injection following the method, described by the Italian medical Giuseppe Tranchina in 1835. The mummified body belongs to Gaetano Arrighi, a prisoner in the Leghorn fortress. He was born in Arezzo in 1789 and died on March 1836 at the age of 47 in the Civil Hospital of Leghorn following pleurisy, as results in an annexed document. The day after his death Dr. Raimondo Barsanti from Pisa and Superintendent at the Leghorn hospital made up the Tranchina's method, which consisted in the injection of an arsencial -mercury solution inside of the blood vessels, giving rigidity and dark red color to the dead body. The excellent outcome of the intervention has made it possible, more than 160 years later, to study not only the method by which Arrighi's body was embalmed but also to perform a careful paleopathological imaging study by traditional X-rays and by Computer

  1. Effect of noninvasive mechanical ventilation in elderly patients with hypercapnic acute-on-chronic respiratory failure and a do-not-intubate order

    Directory of Open Access Journals (Sweden)

    Paolo Scarpazza

    2008-10-01

    Full Text Available Paolo Scarpazza1, Cristoforo Incorvaia2, Giuseppe di Franco1, Stefania Raschi1, Pierfranco Usai1, Monica Bernareggi1, Cristiano Bonacina1, Chiara Melacini1, Silvia Vanni1, Serena Bencini1, Chiara Pravettoni2, Giuseppe Di Cara3, Mona-Rita Yacoub4, Gian Galeazzo Riario-Sforza2, Enrico Guffanti5, Walter Casali11Divisione di Broncopneumotisiologia, Ospedale Civile, Vimercate, Italy; 2Pulmonary rehabilitation, Istituti Clinici di Perfezionamento, Milan, Italy; 3University Department of Medical and Surgical Specialties and Public Health, Perugia, Italy; 4Allergy and Immunology Unit, IRCCS San Raffaele Hospital, Milan, Italy; 5Pulmonary rehabilitation, INRCA, Casatenovo, ItalyAbstract: Noninvasive mechanical ventilation (NIMV is effective in the treatment of patients with acute respiratory failure (ARF. It proved to reduce the need of endotracheal intubation (ETI, the incidence of ETI-associated pneumonia, and mortality compared to nonventilated patients. A particular aspect concerns the outcome of NIMV in patients referring to an emergency room (ER for ARF, and with a do-not-intubate (DNI status due to advanced age or critical conditions. The aim of our study is to assess the outcome of NIMV in a group of elderly patients with acute hypercapnic ARF who had a DNI status. An overall number of 62 subjects (30 males, 32 females, mean age 81 ± 4.8 years, range 79–91 years referred to our semi-intensive respiratory department were enrolled in the study. The underlying diseases were severe chronic obstructive pulmonary disease (COPD in 50/62 subjects, restrictive thoracic disorders in 7/62 subjects, and multiorgan failure in 5/62 subjects. Fifty-four/62 patients were successfully treated with NIMV while 2/62 did not respond to NIMV and were therefore submitted to ETI (one survived. Among NIMV-treated patients, death occurred in 6 patients after a mean of 9.9 days; the overall rate of NIMV failure was 12.9%. Negative prognostic factors for NIMV response

  2. Update on the clinical use of the low-molecular-weight heparin, parnaparin

    Directory of Open Access Journals (Sweden)

    Giuseppe Camporese

    2009-09-01

    Full Text Available Giuseppe Camporese1, Enrico Bernardi2, Franco Noventa31Unit of Angiology and 3Department of Clinical and Experimental Medicine, Clinical Epidemiology Group, University Hospital of Padua, Italy; 2Department of Emergency and Accident Medicine, Hospital of Conegliano Veneto, ItalyAbstract: Parnaparin is a low-molecular-weight heparin that has widely shown its efficacy and safety in prevention of venous thromboembolism, in the treatment of chronic venous disorders, and in the treatment of venous and arterial (stable and unstable angina, acute ST-segment elevation myocardial infarction thrombosis. Parnaparin at the respective dosages of 3200, 4250, 6400, or 12800 IUaXa for a period ranging from 3 to 5 days to 6 months, is usually administered subcutaneously by means of once-daily regimen and is better tolerated than unfractionated heparin at the injection site. In the variety of commercially available low-molecular-weight heparins, parnaparin represents a useful therapeutic option, even though little evidence is available comparing the superiority or the equivalent efficacy and safety of parnaparin to that of the unfractionated heparin or placebo. This review summarizes the available literature on the use of parnaparin in different settings of cardiovascular diseases, including papers published during the past year and ongoing studies.Keywords: low-molecular-weight heparin, heparin, parnaparin, acute coronary syndromes, venous thromboembolism

  3. Volumetric capnography: In the diagnostic work-up of chronic thromboembolic disease

    Directory of Open Access Journals (Sweden)

    Marcos Mello Moreira

    2010-05-01

    Full Text Available Marcos Mello Moreira1, Renato Giuseppe Giovanni Terzi1, Laura Cortellazzi2, Antonio Luis Eiras Falcão1, Heitor Moreno Junior2, Luiz Cláudio Martins2, Otavio Rizzi Coelho21Department of Surgery, 2Department of Internal Medicine, State University of Campinas, School of Medical Sciences, Campinas, Sao Paulo, BrazilAbstract: The morbidity and mortality of pulmonary embolism (PE have been found to be related to early diagnosis and appropriate treatment. The examinations used to diagnose PE are expensive and not always easily accessible. These options include noninvasive examinations, such as clinical pretests, ELISA D-dimer (DD tests, and volumetric capnography (VCap. We report the case of a patient whose diagnosis of PE was made via pulmonary arteriography. The clinical pretest revealed a moderate probability of the patient having PE, and the DD result was negative; however, the VCap associated with arterial blood gases result was positive. The patient underwent all noninvasive exams following admission to hospital and again eight months after discharge. Results gained from invasive tests were similar to those produced by image exams, highlighting the importance of VCap as an important noninvasive tool.Keywords: pulmonary embolism, pulmonary hypertension, volumetric capnography, d-dimers, pretest probability

  4. La Casa del Fascio di Como e le sue

    Directory of Open Access Journals (Sweden)

    Cristina Casero

    2010-01-01

    Full Text Available Giuseppe Terragni’s ‘Casa del Fascio’ in Como undoubtedly stands out as a masterpiece of Italian ‘Razionalismo’, though inflected according to the architect’s peculiar language. However, as rightly noted by Diane Ghirardo, a merely formal analysis of the building is not plausible. The underlying meaning and the very value of the ‘Casa del Fascio’ are fully perceivable only by taking into consideration the original project, without overlooking the opulent ‘decoration’ specifically intended as an integral part of the building. That includes Marcello Nizzoli’s photomechanical panels for the façade, built but never actually put in place, and Mario Radice’s works for the ‘Sala del Direttorio’ and the ‘Salone delle Adunate’, both destroyed in the immediate post-war; also worth mentioning are the decorative projects by the architect himself for the ‘Sala Federale’ and the room entitled to Gigi Maino. From such a perspective, the ‘Casa del Fascio’ appears under a renovated light, as a building of great functional value, but also as a very interesting communicational device.

  5. Zonisamide in the management of epilepsy in the elderly

    Directory of Open Access Journals (Sweden)

    Romigi A

    2015-06-01

    Full Text Available Andrea Romigi,1,2 Eti A Femia,3 Cinzia Fattore,4 Giuseppe Vitrani,1 Giancarlo Di Gennaro,1 Valentina Franco4 1Istituto Neurologico Mediterraneo, IRCCS Neuromed, Pozzilli (IS, Italy; 2Neurophysiopathology Department, University of Rome Tor Vergata, Rome, Italy; 3Dipartimento di Scienze della Salute, Università degli Studi di Milano, Milano, Italy; 4Clinical Trial Centre & Antiepileptic Drugs, C. Mondino National Neurological Institute, Pavia, Italy Abstract: Zonisamide (ZNS, a second-generation antiepileptic drug, indicated as add-on treatment of focal epilepsy, has been recently approved as monotherapy for the treatment of partial seizures in adults affected by newly diagnosed epilepsy in Europe. Evidence on the efficacy and tolerability of antiepileptic drugs in the elderly is still lacking as these patients are frequently excluded from clinical trials. Here, a comprehensive overview of available data regarding the use of ZNS in the treatment of epilepsy in elderly people is provided. In a pooled analysis conducted in patients aged ≥65 years, no new/unexpected safety findings have emerged. Few data from uncontrolled investigations suggest that ZNS may be effective and well tolerated when administered as monotherapy or adjunctive antiepileptic treatment in the elderly. However, evidence from these observational studies is less than satisfactory, and randomized controlled trials focused on these patients are still needed. Keywords: zonisamide, elderly, epilepsy, safety, efficacy

  6. 50 years ago...

    CERN Multimedia

    Laëtitia Pedroso

    2010-01-01

    After completing her university studies in Italy, where it was not all that rare to come across female physicists, Maria Fidecaro arrived at CERN in 1956. Although men were certainly in the majority, they were all just colleagues and gender was irrelevant.    Giuseppe and Maria Fidecaro in 1963, surrounded by spark chambers, inside the detector for the experiment on the decay of a rho meson into a pi meson and a photon. Maria Fidecaro is no stranger to CERN and the field of research, having watched them develop over many years. "In the early days we worked in small teams of no more than two or three people", she recalls. "As in Italy, I was not the only woman involved in research at CERN. Men and women alike, our common goal was to understand physics and conduct experiments." Clearly, juggling an exciting job and looking after a family of four children didn't make for an easy life. "At that time society was different and there were few cr&...

  7. Anila Hanxhari (Durrës, 1974

    Directory of Open Access Journals (Sweden)

    María Antonia Blat Mir

    2017-01-01

    Full Text Available Anila Hanxhari nació en Durrës (Albania y vive en Lanciano (Italia. Es poetisa, pintora, narradora, traductora y presidenta de la asociación cultural Italfida, con la que ha ideado y organizado diversas actividades culturales y congresos internacionales. Actualmente es directora responsable del sector cultural de Ascom Abruzzo ocupándose de la iniciativa “Poesia e Impresa”. Ha publicado las antologías de poesía Io tu e l’Anima (Ianieri, 1997, Assopita erba dell’est (Noubs, 2002, Cicatrici d’acqua (Noubs, 2007, con prólogo de Giuseppe Conte, Brindisi degli angeli (La Vita Felice, 2012, con prólogo de Maurizio Cucchi, Tiro a sorte la libertà (Tabula Fati, 2016, con prólogo de Davide Rondoni y Rolando D’Alonzo. Sus poemas han aparecido, entre otras, en las antologías Nuovissima poesia italiana (Oscar Mondadori, 2005, editada por Antonio Riccardi y Maurizio Cucchi, La parola che ricostruisce. Poeti italiani per l’Aquila (Tracce, 2009, además de en la colección Specchio de La Stampa y en numerosas revistas. Ha ganado diferentes premios, como el Premio Camaiore-Proposta (2002, el Premio Matacotta a la opera prima 2003, el Premio Valle Senio o el premio Poesia nella vita (2011.

  8. Clinical utility of circulating tumor cell counting through CellSearch®: the dilemma of a concept suspended in Limbo

    Directory of Open Access Journals (Sweden)

    Raimondi C

    2014-04-01

    Full Text Available Cristina Raimondi,1 Angela Gradilone,1 Giuseppe Naso,2 Enrico Cortesi,2 Paola Gazzaniga1 1Dipartimento Medicina Molecolare, Sapienza Università di Roma, Rome, Italy; 2Dipartimento di Scienze Radiologiche, Oncologiche e Anatomopatologiche, Sapienza Università di Roma, Rome, Italy Abstract: To date, 10 years after the first demonstration of circulating tumor cells (CTCs, prognostic significance in metastatic breast cancer using the US Food and Drug Administration–cleared system CellSearch®, the potential utility of CTCs in early clinical development of drugs, their role as a surrogate marker of response to therapy, and their molecular analysis for patient stratification for targeted therapies are still major unsolved questions. Great expectations are pinned on the ongoing interventional trials aimed to demonstrate that CTCs might be of value for guiding treatment of patients and predicting cancer progression. To fill the gap between theory and practice with regard to the clinical utility of CTCs, a bridge is needed, taking into account innovative design for clinical trials, a revised definition of traditional CTCs, next-generation CTC technology, the potential clinical application of CTC analysis in non-validated settings of disease, and finally, expanding the number of patients enrolled in the studies. In this regard, the results of the first European pooled analysis definitely validated the independent prognostic value of CTC counting in metastatic breast cancer patients. Keywords: CTC, clinical trials, prognosis

  9. Current options for the treatment of Paget’s disease of the bone

    Directory of Open Access Journals (Sweden)

    Daniela Merlotti

    2009-07-01

    Full Text Available Daniela Merlotti, Luigi Gennari, Giuseppe Martini, Ranuccio NutiDepartment of Internal Medicine, Endocrine-Metabolic Sciences and Biochemistry, University of Siena, Siena, ItalyAbstract: Paget’s disease of bone (PDB is a chronic bone remodeling disorder characterized by increased osteoclast-mediated bone resorption, with subsequent compensatory increases in new bone formation, resulting in a disorganized mosaic of woven and lamellar bone at affected skeletal sites. This disease is most often asymptomatic but can be associated with bone pain or deformity, fractures, secondary arthritis, neurological complications, deafness, contributing to substantial morbidity and reduced quality of life. Neoplastic degeneration of pagetic bone is a relatively rare event, occurring with an incidence of less than 1%, but has a grave prognosis. Specific therapy for PDB is aimed at decreasing the abnormal bone turnover and bisphosphonates are currently considered the treatment of choice. These treatments are associated with a reduction in plasma alkaline phosphatase (ALP activity and an improvement in radiological and scintigraphic appearance and with a reduction in bone pain and bone deformity, Recently, the availability of newer, more potent nitrogen-containing bisphosphonates has improved treatment outcomes, allowing a more effective and convenient management of this debilitating disorder.Keywords: Paget’s disease of bone, bisphosphonates, aminobisphosphonates, bone remodeling

  10. Looking at our origins

    CERN Document Server

    Nairucu Arts

    2011-01-01

    Exhibition by Nairucu-Arts, in collaboration with the Anthropology Museum Giuseppe Sergi, Università la Sapienza, Roma, Italy and ECOLINT, Campus des Nations. The exhibition comprises: posters (in English and French) intended for a large audience with text from Prof. Giorgio Manzi, Julia Rizzo, Fabio Di Vincenzo, illustrated with art drawings from Carlo Ranzi, Italy. The exhibition will also present drawings from the students of the Art Classes of Karin Bain and Fabien Bruttin at ECOLINT,Geneva. On 2nd March at 5 p.m. you will be welcomed with a drink before the conference that will be given in English at 6 p.m in the CERN Council Room by Wim De Geest, a retired Professor from KUB (Catholic University of Brussels). Title: There's no language like our language, like no language we know. But how did it evolve? A summary in French will be made available for the public. http://association.web.cern.ch/association/en/OtherActivities/Origins.html

  11. Manipulation of tumor oxygenation and radiosensitivity through modification of cell respiration. A critical review of approaches and imaging biomarkers for therapeutic guidance.

    Science.gov (United States)

    Gallez, Bernard; Neveu, Marie-Aline; Danhier, Pierre; Jordan, Bénédicte F

    2017-08-01

    Tumor hypoxia has long been considered as a detrimental factor for the response to irradiation. In order to improve the sensitivity of tumors cells to radiation therapy, tumor hypoxia may theoretically be alleviated by increasing the oxygen delivery or by decreasing the oxygen consumption by tumor cells. Mathematical modelling suggested that decreasing the oxygen consumption should be more efficient than increasing oxygen delivery in order to alleviate tumor hypoxia. In this paper, we review several promising strategies targeting the mitochondrial respiration for which alleviation of tumor hypoxia and increase in sensitivity to irradiation have been demonstrated. Because the translation of these approaches into the clinical arena requires the use of pharmacodynamics biomarkers able to identify shift in oxygen consumption and tumor oxygenation, we also discuss the relative merits of imaging biomarkers (Positron Emission Tomography and Magnetic Resonance) that may be used for therapeutic guidance. This article is part of a Special Issue entitled Mitochondria in Cancer, edited by Giuseppe Gasparre, Rodrigue Rossignol and Pierre Sonveaux. Copyright © 2017 Elsevier B.V. All rights reserved.

  12. Anti-TNF therapy for juvenile idiopathic arthritis-related uveitis

    Directory of Open Access Journals (Sweden)

    Semeraro F

    2014-03-01

    Full Text Available Francesco Semeraro,1 Barbara Arcidiacono,2 Giuseppe Nascimbeni,1 Martina Angi,1 Barbara Parolini,2 Ciro Costagliola31Eye Clinic, Department of Neurological Sciences and Vision, University of Brescia, Brescia, Italy; 2Department of Ophthalmology, S. Anna Hospital, Brescia, Italy; 3Eye Clinic, Department of Health Sciences, University of Molise, Campobasso, ItalyAbstract: Juvenile idiopathic arthritis-related uveitis is the most common type of uveitis in childhood and one of the main causes of visual impairment in children. The introduction of biological treatment has widened the range of therapeutic options for children with uveitis refractory to standard nonbiologic immunosuppressants. Data from clinical trials suggest that both adalimumab and infliximab have demonstrated effectiveness and safety in open-label studies, although no large, randomized, controlled trials have been reported so far. The role of etanercept in treating juvenile idiopathic arthritis-related uveitis is not yet well defined. In our experience, anti-tumor necrosis factor therapy has been shown to be more effective than steroids and/or methotrexate in treating uveitis. Up to now, tumor necrosis factor blocking compounds have been reserved for the treatment of the most severe cases of refractory uveitis, and larger prospective clinical trials are required in order to better assess the safety of these new compounds.Keywords: adalimumab, etanercept, infliximab

  13. History of the discovery of the malaria parasites and their vectors

    Directory of Open Access Journals (Sweden)

    Cox Francis EG

    2010-02-01

    Full Text Available Abstract Malaria is caused by infection with protozoan parasites belonging to the genus Plasmodium transmitted by female Anopheles species mosquitoes. Our understanding of the malaria parasites begins in 1880 with the discovery of the parasites in the blood of malaria patients by Alphonse Laveran. The sexual stages in the blood were discovered by William MacCallum in birds infected with a related haematozoan, Haemoproteus columbae, in 1897 and the whole of the transmission cycle in culicine mosquitoes and birds infected with Plasmodium relictum was elucidated by Ronald Ross in 1897. In 1898 the Italian malariologists, Giovanni Battista Grassi, Amico Bignami, Giuseppe Bastianelli, Angelo Celli, Camillo Golgi and Ettore Marchiafava demonstrated conclusively that human malaria was also transmitted by mosquitoes, in this case anophelines. The discovery that malaria parasites developed in the liver before entering the blood stream was made by Henry Shortt and Cyril Garnham in 1948 and the final stage in the life cycle, the presence of dormant stages in the liver, was conclusively demonstrated in 1982 by Wojciech Krotoski. This article traces the main events and stresses the importance of comparative studies in that, apart from the initial discovery of parasites in the blood, every subsequent discovery has been based on studies on non-human malaria parasites and related organisms.

  14. Improvement of gross motor and cognitive abilities by an exercise training program: three case reports

    Directory of Open Access Journals (Sweden)

    Alesi M

    2014-03-01

    Full Text Available Marianna Alesi,1 Giuseppe Battaglia,2 Michele Roccella,1 Davide Testa,1 Antonio Palma,2 Annamaria Pepi1 1Department of Psychology, 2Department of Law, Social and Sport Science, University of Palermo, Palermo, Italy Background: This work examined the efficacy of an integrated exercise training program (coach and family in three children with Down syndrome to improve their motor and cognitive abilities, in particular reaction time and working memory. Methods: The integrated exercise training program was used in three children with Down syndrome, comprising two boys (M1, with a chronological age of 10.3 years and a mental age of 4.7 years; M2, with a chronological age of 14.6 years and a mental age of less than 4 years and one girl (F1, chronological age 14.0 years and a mental age of less than 4 years. Results: Improvements in gross motor ability scores were seen after the training period. Greater improvements in task reaction time were noted for both evaluation parameters, ie, time and omissions. Conclusion: There is a close interrelationship between motor and cognitive domains in individuals with atypical development. There is a need to plan intervention programs based on the simultaneous involvement of child and parents and aimed at promoting an active lifestyle in individuals with Down syndrome. Keywords: disability, Down syndrome, gross motor abilities, cognitive abilities, physical activity

  15. Conferenze scelte

    CERN Document Server

    Fantappiè, Luigi

    1993-01-01

    L'opera scientifica di Luigi Fantappiè (1901-1956) si può dividere in tre tappe fondamentali : a) Dal 1923 al 1941 egli si occupò prevalentemente della Teoria dei funzionali analitici, da lui stesso creata. b) Nel 1942 propose la Teoria unitaria del mondo fisico e biologico, completata nel 1947, con l'introduzione del nuovo concetto di "esistenza totale", compatibile con i principi della relatività. c) A partire dal 1952 sviluppò la Teoria degli universi fisici, basata sulla teoria dei gruppi, e nel 1954 dimostrò che la relatività ristretta di Einstein risulta un caso limite di una teoria più perfezionata, la relatività finale. In questo volume vengono presentate alcune conferenze nelle quali Fantappiè espone in forma semplice e divulgativa le sue idee, alla ricerca di una visione armonica ed unitaria del cosmo e della vita. Il lavoro è stato curato dal suo allievo Giuseppe Arcidiacono.

  16. Dabrafenib: a new opportunity for the treatment of BRAF V600-positive melanoma

    Directory of Open Access Journals (Sweden)

    Banzi M

    2016-05-01

    Full Text Available Maria Banzi,1 Simona De Blasio,2 Aimilios Lallas,3 Caterina Longo,2 Elvira Moscarella,2 Roberto Alfano,4 Giuseppe Argenziano5 1Department of Medical Oncology, Arcispedale Santa Maria Nuova IRCCS, Reggio Emilia, Italy; 2Skin Cancer Unit, Arcispedale Santa Maria Nuova IRCCS, Reggio Emilia, Italy; 3First Department of Dermatology, Aristotle University, Thessaloniki, Greece; 4Department of Anesthesiology, Surgery and Emergency, 5Dermatology Unit, Second University of Naples, Naples, Italy Abstract: Prior to 2011, the 1-year survival rates for patients suffering from advanced or metastatic melanoma was as low as 33%, with a median overall survival of about 9 months. Several chemotherapeutic regimens have been applied, either as monochemotherapy or as polychemotherapy, overall not resulting in an improvement of progression-free or overall survival. Novel insights into the epidemiology and biology of melanoma allowed the development of newer therapies. The discovery of mutations in BRAF, a part of the mitogen-activated protein kinase, allowed the development of two BRAF inhibitors, vemurafenib and dabrafenib, which significantly improved the outcome of metastatic melanoma treatment. This article reviews the mechanism of action, efficacy, and safety profile of dabrafenib. An in-depth knowledge of this medication will encourage clinicians to select the appropriate therapeutic strategy for each patient, as well as to prevent or adequately manage side effects, optimizing, thus, the drug’s applicability. Keywords: melanoma, BRAF, target therapy, dabrafenib, melanoma survival

  17. Dynamic interactions between musical, cardiovascular, and cerebral rhythms in humans.

    Science.gov (United States)

    Bernardi, Luciano; Porta, Cesare; Casucci, Gaia; Balsamo, Rossella; Bernardi, Nicolò F; Fogari, Roberto; Sleight, Peter

    2009-06-30

    Reactions to music are considered subjective, but previous studies suggested that cardiorespiratory variables increase with faster tempo independent of individual preference. We tested whether compositions characterized by variable emphasis could produce parallel instantaneous cardiovascular/respiratory responses and whether these changes mirrored music profiles. Twenty-four young healthy subjects, 12 musicians (choristers) and 12 nonmusician control subjects, listened (in random order) to music with vocal (Puccini's "Turandot") or orchestral (Beethoven's 9th Symphony adagio) progressive crescendos, more uniform emphasis (Bach cantata), 10-second period (ie, similar to Mayer waves) rhythmic phrases (Giuseppe Verdi's arias "Va pensiero" and "Libiam nei lieti calici"), or silence while heart rate, respiration, blood pressures, middle cerebral artery flow velocity, and skin vasomotion were recorded.Common responses were recognized by averaging instantaneous cardiorespiratory responses regressed against changes in music profiles and by coherence analysis during rhythmic phrases. Vocal and orchestral crescendos produced significant (P=0.05 or better) correlations between cardiovascular or respiratory signals and music profile, particularly skin vasoconstriction and blood pressures, proportional to crescendo, in contrast to uniform emphasis, which induced skin vasodilation and reduction in blood pressures. Correlations were significant both in individual and group-averaged signals. Phrases at 10-second periods by Verdi entrained the cardiovascular autonomic variables. No qualitative differences in recorded measurements were seen between musicians and nonmusicians. Music emphasis and rhythmic phrases are tracked consistently by physiological variables. Autonomic responses are synchronized with music, which might therefore convey emotions through autonomic arousal during crescendos or rhythmic phrases.

  18. Dianella Selvatico Estense

    Directory of Open Access Journals (Sweden)

    José Molina

    2014-06-01

    Full Text Available Dianella Selvatico Estense nace en Padova en 1936 y muere en Cortina d’Ampezzo en 1999. Poeta y traductora, Selvatico es un claro ejemplo de la importancia que cobra la traducción en el quehacer poético de una lengua. Sus poemas recurren constantemente a callejones lingüísticos propios de la lengua italiana, haciendo el guiño de su propia labor a sus futuros corresponsales. Tradujo del francés y del inglés para la casa editorial Einaudi a autores como Simone de Beauvoir, Guy de Maupassant, Pierre Jean Jouve y Michael Crichton, entre otros. Sus publicaciones incluyen los libros de poemas Si è sfogliata una rosa (1958, Quando il giorno sarà compiuto (1960, Un giorno all’improvviso (1964 y Nel breve Cerchio (1988. Es autora también de la novela Il senso delle cose (1967. Fue amiga del poeta Giuseppe Ungaretti, quien prologó dos de sus libros. Los poemas presentados aquí forman parte de su poesía póstuma, publicada por Campanotto Editore en el año 2001.

  19. Survey report for fiscal 1998. Joint research project with researchers related to petroleum substituting energies in the EU countries; 1998 nendo EU shokoku no sekiyu daitai energy kanren kenkyusha tono kyodo kenkyu jigyo chosa hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    It was intended to invite researchers related to petroleum substituting energies from the EU countries to perform joint researches at research organizations under the auspices of the Agency of Industrial Science and Technology having deep relations with research themes of the invited researchers, to deepen the mutual understanding, and to form efficient cooperative relationship. The intention is also to contribute to research and development of petroleum substituting energies to be used in Japan in the future. The research themes, researchers, their research organizations, and the receiving research organizations are as follows: (1) evaluation of reservoir impedance in high-temperature rock experimental fields by Mr. Ralph Weidler (Germany) at Ruhr University received by the Resource and Environmental Technology Research Institute; (2) changing the particle boundary structure of ceramics by using the alkoxide process by Dr. Ramon Torrecillas (Spain) at Institute Nacional del Carbon received by the Nagoya Industrial Technology Research Institute; (3) research on corrosion in metallic materials for molten carbonate type fuel cells by Dr. Giuseppe Calogero (Italy) at Institute for Transformation and Storage of Energy received by the Osaka Industrial Technology Research Institute; and (4) estimation of behavior of deep geothermal reservoirs with high enthalpy by Dr. Enrico Maranini at Universita' Di Ferrara received by the Geology Survey Center. (NEDO)

  20. The Use of FTIR and Micro-FTIR Spectroscopy: An Example of Application to Cultural Heritage

    International Nuclear Information System (INIS)

    La Russa, M.F.; Ruffolo, S.A.; Crisci, G.M.; Barone, G.; Mazzoleni, P.; Pezzino, A.

    2011-01-01

    Micro-FTIR and FTIR spectroscopy is useful for the study of degradation forms of cultural heritage. In particular it permits to identify the degradation phases and to establish the structural relationship between them and the substratum. In this paper, we report the results obtained on marble from a Roman sarcophagus, located in the medieval cloister of St. Cosimato Convent (Rome), and on oolitic limestone from the facade of St. Giuseppe Church in Syracuse (Sicily). The main components found in the samples of both monuments are: gypsum, calcium oxalate, and organic matter due to probably conservation treatments. In particular, the qualitative distribution maps of degradation products, obtained by means of micro-FTIR operating in ATR mode, revealed that the degradation process is present deep inside the stones also if it is not visible macroscopically. This process represents the main cause of crumbling of the substrate. The results of this research highlight the benefits of the μ-FTIR analysis providing useful insights on the polishing and consolidation processes of stone materials

  1. James V. Allaby (1936-2009)

    CERN Multimedia

    2009-01-01

    Jim Allaby standing in front of the target calorimeter of the CHARM neutrino experiment (WA18) .It was with shock and sorrow that we heard Jim Allaby passed away on 7 April. Jim was born in Preston, England, in October 1936. After obtaining a first degree in physics at King’s College, London, he moved to Liverpool to study for his PhD at the university’s synchrocyclotron. This was his first proton-proton scattering experiment, and was also the start of a lifelong friendship with Bert Diddens, who was there as a CERN fellow. In the early 1960s Jim moved to SLAC where he worked with Dave Ritson on electron inelastic scatterings. Ritson greatly appreciated Jim’s calm and systematic approach to any kind of problem he was confronted with. Thus it was natural for Jim to visit SLAC later and for Ritson to join the DELPHI Collaboration in the 1990s. Jim came to CERN in the summer of 1965. He joined the CERN group of Giuseppe Coc...

  2. James V. Allaby (1936-2009)

    CERN Multimedia

    2009-01-01

    It was with shock and sorrow that we heard Jim Allaby passed away on 7 April. Jim was born in Preston, England, in October 1936. After obtaining a first degree in physics at King’s College, London, he moved to Liverpool to study for his PhD at the university’s synchrocyclotron. This was his first proton-proton scattering experiment, and was also the start of a lifelong friendship with Bert Diddens, who was there as a CERN fellow. In the early 1960s Jim moved to SLAC where he worked with Dave Ritson on electron inelastic scatterings. Ritson greatly appreciated Jim’s calm and systematic approach to any kind of problem he was confronted with. Thus it was natural for Jim to visit SLAC later and for Ritson to join the DELPHI Collaboration in the 1990s. Jim came to CERN in the summer of 1965. He joined the CERN group of Giuseppe Cocconi, Bert Diddens and Alan Wetherell, who were preparing proton-proton scattering experiments, in a s...

  3. Suicide risk in depression and bipolar disorder: Do impulsiveness-aggressiveness and pharmacotherapy predict suicidal intent?

    Directory of Open Access Journals (Sweden)

    Maurizio Pompili

    2008-03-01

    Full Text Available Maurizio Pompili1,2, Marco Innamorati3, Michele Raja4, Ilaria Falcone2, Giuseppe Ducci5, Gloria Angeletti2, David Lester6, Paolo Girardi2, Roberto Tatarelli2, Eleonora De Pisa21McLean Hospital, Harvard Medical School, Boston, MA, USA; 2Department of Psychiatry, Sant’Andrea Hospital, “Sapienza” University of Rome, Italy; 3Università Europea di Roma, Italy; 4Diagnostic and Therapeutic Psychiatric Services, Department of Mental Health, Santo Spirito Hospital, Rome, Italy; 5Diagnostic and Therapeutic Psychiatric Services, Department of Mental Health, San Filippo Neri Hospital, Rome, Italy; 6Center for the Study of Suicide, Blackwood, NJ, USAAbstract: The aims of the present study were to examine clinical, personality, and sociodemographic predictors of suicide risk in a sample of inpatients affected by major affective disorders. The participants were 74 inpatients affected by major depressive disorder or bipolar disorder-I. Patients completed a semi-structured interview, the Beck Hopelessness Scale, the Aggression Questionnaire, the Barratt Impulsiveness Scale, and the Hamilton scales for depression and anxiety. Over 52% of the patients were high suicide risks. Those at risk reported more severe depressive-anxious symptomatology, more impulsivity and more hostility. Impulsivity, the use of antidepressants, anxiety/somatization, and the use of mood stabilizers (a negative predictor resulted in accurate predicting of suicide intent. Impulsivity and antidepressant use were the strongest predictors even after controlling for several sociodemographic and clinical variables.Keywords: suicide, mood disorders, pharmacotherapy, impulsiveness, aggressiveness

  4. Long-term treatment of rheumatoid arthritis with adalimumab

    Directory of Open Access Journals (Sweden)

    Murdaca G

    2013-05-01

    Full Text Available Giuseppe Murdaca, Francesca Spanò, Francesco PuppoDepartment of Internal Medicine, Clinical Immunology Unit, University of Genoa, Genoa, ItalyAbstract: Rheumatoid arthritis (RA is a chronic inflammatory disease that is associated with joint damage and progressive disability, an increased risk of morbidity related to comorbid conditions and substantial socioeconomic costs. Tumor necrosis factor-alpha (TNF-α is a proinflammatory cytokine known to have a central role in the initial host response to infection and in the pathogenesis of various immune-mediated diseases, such as RA, ankylosing spondylitis, psoriasis and/or psoriatic arthritis, Crohn’s disease, and systemic lupus erythematosus. Five TNF-α inhibitors are available for the clinical use: infliximab; adalimumab; etanercept; golimumab; and certolizumab pegol. Infliximab is a chimeric human/murine IgG1 monoclonal antibody (mAb; adalimumab, and golimumab are human mAbs; certolizumab pegol is composed of the fragment antigen-binding anti-binding domain of a humanized anti-TNF-α mAb, combined with polyethylene glycol to increase its half-life in the body; etanercept is a fusion protein that acts as a “decoy receptor” for TNF-α. In this paper, we will briefly review the current data on efficacy and safety of adalimumab in patients with RA, its potential beneficial effects upon comorbid conditions, such as endothelial dysfunction and accelerated atherosclerosis in RA, and the immunogenicity.Keywords: adalimumab, efficacy, safety, rheumatoid arthritis, VEGF, immunogenicity, infections

  5. The effect of a cognitive-motor intervention on voluntary step execution under single and dual task conditions in older adults: a randomized controlled pilot study

    Directory of Open Access Journals (Sweden)

    Pichierri G

    2012-07-01

    Full Text Available Giuseppe Pichierri,1 Amos Coppe,1 Silvio Lorenzetti,2 Kurt Murer,1 Eling D de Bruin11Institute of Human Movement Sciences and Sport, Department of Health Sciences and Technology, ETH Zurich, Switzerland; 2Institute for Biomechanics, Department of Health Sciences and Technology, ETH Zurich, SwitzerlandBackground: This randomized controlled pilot study aimed to explore whether a cognitive-motor exercise program that combines traditional physical exercise with dance video gaming can improve the voluntary stepping responses of older adults under attention demanding dual task conditions.Methods: Elderly subjects received twice weekly cognitive-motor exercise that included progressive strength and balance training supplemented by dance video gaming for 12 weeks (intervention group. The control group received no specific intervention. Voluntary step execution under single and dual task conditions was recorded at baseline and post intervention (Week 12.Results: After intervention between-group comparison revealed significant differences for initiation time of forward steps under dual task conditions (U = 9, P = 0.034, r = 0.55 and backward steps under dual task conditions (U = 10, P = 0.045, r = 0.52 in favor of the intervention group, showing altered stepping levels in the intervention group compared to the control group.Conclusion: A cognitive-motor intervention based on strength and balance exercises with additional dance video gaming is able to improve voluntary step execution under both single and dual task conditions in older adults.Keywords: fall prevention, exercise, dance, video game

  6. 1861-1981: Statistics teaching in Italian universities

    Directory of Open Access Journals (Sweden)

    Donata Marasini

    2013-05-01

    Full Text Available This paper aims to outline the development of Statistics from 1861 to 1981 with respect to its contents. The paper pays particular attention to some statistical topics which have been covered by basic introductory courses in the Italian Universities since the beginning of the Italian unification. The review takes as its starting point the well-known book “Filosofia della Statistica” of Melchiorre Gioja. This volume was published 35 years before Italian unification but it already contains the fundamental topics of exploratory and inductive Statistics. These topics give the opportunity to mention Italian statisticians who are considered the pioneers of this discipline. In particular, the attention is focused on four statisticians: Corrado Gini, well-known for its modern insights; Marcello Boldrini, high cultured man also in the epistemological field; Bruno de Finetti, founder of subjective school and Bayesian reasoning; Giuseppe Pompilj, precursor of random variables and sampling theory. The paper browses the indexes of three well-known Italian handbooks that, although published after the period 1861-1981, deal with topics covered in some basic teachings of exploratory statistics, statistical inference and sampling theory from finite population.

  7. Dysonian SETI as a "Shortcut" to Detecting Habitable Planets

    Science.gov (United States)

    Wright, J. T.

    2016-12-01

    The search for habitable planets is ultimately motivated by the search for inhabited planets. On Earth, the most telling signature of life is that of humanity's technology. The Search for Extraterrestrial Intelligence (SETI) is thus the "ultimate" search for habitable planets.In 1960 two seminal papers in SETI were published, providing two visions for SETI. Giuseppe Cocconi and Philip Morrison's proposed detecting deliberate radio signals ("communication SETI"), while Freeman Dyson ("artifact SETI"), proposed detecting the inevitable effects of massive energy supplies and artifacts on their surroundings. While communication SETI has now had many career-long practitioners and major efforts, artifact SETI has, until recently, not been a vibrant field of study. The launch of the Kepler and WISE satellites have greatly renewed interest in the field, however, and the recent Breakthrough Listen Initiative has provided new motivation for finding good targets for communication SETI. I will discuss the progress of the Ĝ Search for Extraterrestrial Civilizations with Large Energy Supplies, including its justification and motivation, waste heat search strategy and first results, and the framework for a search for megastructures via transit light curves. The last of these led to the identification of KIC 8462852 (a.k.a. "Tabby's Star") as a candidate ETI host. This star, discovered by Boyajian and the Zooniverse Planet Hunters, exhibits several apparently unique and so-far unexplained photometric properties, and continues to confound natural explanation.

  8. La Traviata (Verdi, 1853 sob a ótica da tradução poética: Vertendo “Un dì felice, eterea” para o português e o inglês

    Directory of Open Access Journals (Sweden)

    Andréia Riconi

    2016-03-01

    Full Text Available Este trabalho tem como objetivo refletir sobre o processo de tradução da ária “Un dì felice, eterea”, escrita por Francesco Maria Piave (1810-1876, presente na obra operística La Traviata (1853, composta por Giuseppe Verdi (1813-1901. Para chegar a este escopo, num primeiro momento, traçamos um breve panorama que contextualiza a ópera como gênero musical e textual, bem como tratamos de algumas nuances específicas inerentes a este tipo de produção, que tocam diretamente em nosso trabalho enquanto tradutores. Na segunda parte, trazemos nossas propostas de tradução acompanhadas de comentários acerca da atividade tradutória, dos seus desafios e de nossa busca por soluções que levem em consideração o projeto de tradução ao qual nos propusemos e que foi neste trabalho descrito. Nosso intuito, portanto, é o de fazer uma reflexão, com base em teóricos que se debruçaram sobre questões que envolvem literatura e tradução poética e sobre o que, nesse percurso tradutório, optamos por privilegiar.

  9. Fractal Geometry in the Arts: AN Overview across the Different Cultures

    Science.gov (United States)

    Sala, Nicoletta

    Fractal, in mathematics, is a geometric shape that is complex and detailed in structure at any level of magnification. The word "fractal" was coined less than thirty years ago by one of history's most creative and mathematicians, Benoit Mandelbrot, whose work, The Fractal Geometry of Nature, first introduced and explained concepts underlying this new vision of the geometry. Although other mathematical thinkers like Georg Cantor (1845-1918), Felix Hausdorff (1868-1942), Gaston Julia (1893-1978), Helge von Koch (1870-1924), Giuseppe Peano (1858-1932), Lewis Richardson (1891-1953), Waclaw Sierpinski (1882-1969) and others had attained isolated insights of fractal understanding, such ideas were largely ignored until Mandelbrot's genius forged them at a single blow into a gorgeously coherent and fascinating discipline. Fractal geometry is applied in different field now: engineering, physics, chemistry, biology, and architecture. The aim of this paper is to introduce an approach where the arts are analysed using a fractal point of view.

  10. The effect of nanoparticle uptake on cellular behavior: disrupting or enabling functions?

    Directory of Open Access Journals (Sweden)

    Miserocchi G

    2012-09-01

    Full Text Available Alice Panariti, Giuseppe Miserocchi, Ilaria RivoltaDepartment of Experimental Medicine, University of Milano Bicocca, Monza, ItalyAbstract: Nanoparticles (NPs are materials with overall dimensions in the nanoscale range. They have unique physicochemical properties, and have emerged as important players in current research in modern medicine. In the last few decades, several types of NPs and microparticles have been synthesized and proposed for use as contrast agents for diagnostics and imaging and for drug delivery; for example, in cancer therapy. Yet specific targeting that will improve their delivery still represents an unsolved challenge. The mechanism by which NPs enter the cell has important implications not only for their fate but also for their impact on biological systems. Several papers in the literature discuss the potential risks related to NP exposure, and more recently the concept that even sublethal doses of NPs may elicit a cell response has been proposed. In this review, we intend to present an overall view of cell mechanisms that may be perturbed by cell–NP interaction. Published data, in fact, emphasize that NPs should no longer be viewed only as simple carriers for biomedical applications, but that they can also play an active role in mediating biological effects.Keywords: nanoparticles, uptake, intracellular trafficking, bio compatibility

  11. El médico de Benevento: de la Medicina a la laica Santidad

    Directory of Open Access Journals (Sweden)

    Alberto Enrique D’OTTAVIO

    2016-04-01

    Full Text Available Esta miniserie sobre el médico de Benevento Giuseppe Moscati, poco conocido en Latinoamérica, aunque sencilla desde un punto de vista fílmico, puede resultar altamente aleccionadora para los estudiantes en lo que hace a su ineludible adquisición de valores clave para la práctica médica. Más aún, en el contexto de la sociedad postmoderna y tecnológica que parece haberlos extraviado o perdido. Desarrollado entre su graduación en 1903 y su fallecimiento en 1927, el filme, prescindiendo de las creencias religiosas y del futuro profesional proyectado por los cursantes de la carrera médica, plantea melodramáticamente un conmovedor contraste de comportamientos entrelazando acontecimientos reales y ficcionales. Tal contraste puede que conduzca a los espectadores a mejorar sus vidas profesional y cotidiana con principios que, a la vez, redunden en la superación de la sociedad toda.

  12. 7 July 2011 - Members of the Swiss Federal Council (front row) in front of the Globe of Science and Innovation.

    CERN Multimedia

    Maximilien Brice

    2011-01-01

    CERN-HI-1107166 01 1er rang: La chancelière Corina Casanova, le conseiller fédéral Johann N. Schneider-Ammann, le conseiller fédéral Ueli Maurer, la conseillère fédérale Eveline Widmer-Schlumpf, la conseillère fédérale Simonetta Sommaruga, la Présidente de la Confédération Micheline Calmy-Rey, le Directeur général du CERN Rolf Heuer, la conseillère fédérale Doris Leuthard, le conseiller fédéral Didier Burkhalter. 2è rang: Le vice-chancelier André Simonazzi , le vice-chancelier Thomas Helbling, la chef des relations internationales Felicitas Pauss, le directeur de la recherche et du calcul scientifique Sergio Bertolucci. 3è rang: Les scientifiques suisses: Ulrich Straumann (LHCb, Zürich et délégué suisse au Conseil du CERN), Rainer Wallny (CMS, ETHZ), Günther Dissertori (CMS, ETHZ), Antonio Ereditato (ATLAS, Bern), Tatsuya Nakada (LHCb, EPFL), Olivier Schneider (LHCb, EPFL), Martin Pohl (ATLAS, Genève), Vincenzo Chiochia (CM, Zürich), Giuseppe Iacobucci (ATLAS, Genève), le C...

  13. Guido Vegni (1931 - 2016)

    CERN Multimedia

    2016-01-01

    Guido Vegni, a renowned particle physicist and Professor at the University of Milan, passed away on Thursday, 2 June.   Professor Guido Vegni in 1976, at the Institute for High Energy Physics in Protvino, Russia. Italian physicist Guido Vegni passed away on Thursday, 2 June. With his death we have lost a friend, an excellent physicist and a strong supporter of the CERN programme. His long and fruitful involvement in particle physics started in the mid 1950s, when he joined the Milan nuclear emulsion group led by Giuseppe Occhialini in 1956. His thesis aimed to measure the spin-parity assignment of the K+ meson from its decay into three pions, contributing to the study of the famous "tau-theta puzzle", eventually solved by the discovery of the non-conservation of parity in weak interactions. In 1960, Guido was appointed "Assistant" to Professor G. Occhialini in Milan, the first step of a career that led to him eventually becom...

  14. Winter Atomiades 2014: CERN skiers win 31 medals!

    CERN Multimedia

    CERN Bulletin

    2014-01-01

    The 12th Winter Atomiades took place at Flachau, Austria, from 8 to 15 March 2014. The event, organised by the Association of the Sports Communities of the European Research Institutes (see here), brought together 18 research centres, including CERN, AIT, ESRF, PSI and many others, with a total of about 280 participants.   Lots of fun and a great result for the 13 CERN skiers at the 2014 Winter Atomiades in Flachau, Austria. From left to right and from bottom to top: Lennart Jirden (PH), Anna Lipniacka (PH), Guillaume Michet (DGS), Vera Chetvertkova (TE), Thierry Boileau (external), Jean-Louis Grenard (EN), Clement Bovet (EN), Marc Tavlet (BE), Rob Knoops (PH), Giuseppe Lo Presti (IT), Simone Campana (IT), Sylviane Gander (external) and Javier Pablos (TE).   The team of 13 athletes from six different CERN departments won 31 medals across all disciplines, in a spirit of fun and fair play. CERN came second in the general ranking of all participating institutes! The next Winter Atomiades...

  15. Calcium regulates cell death in cancer: Roles of the mitochondria and mitochondria-associated membranes (MAMs).

    Science.gov (United States)

    Danese, Alberto; Patergnani, Simone; Bonora, Massimo; Wieckowski, Mariusz R; Previati, Maurizio; Giorgi, Carlotta; Pinton, Paolo

    2017-08-01

    Until 1972, the term 'apoptosis' was used to differentiate the programmed cell death that naturally occurs in organismal development from the acute tissue death referred to as necrosis. Many studies on cell death and programmed cell death have been published and most are, at least to some degree, related to cancer. Some key proteins and molecular pathways implicated in cell death have been analyzed, whereas others are still being actively researched; therefore, an increasing number of cellular compartments and organelles are being implicated in cell death and cancer. Here, we discuss the mitochondria and subdomains of the endoplasmic reticulum (ER) that interact with mitochondria, the mitochondria-associated membranes (MAMs), which have been identified as critical hubs in the regulation of cell death and tumor growth. MAMs-dependent calcium (Ca 2+ ) release from the ER allows selective Ca 2+ uptake by the mitochondria. The perturbation of Ca 2+ homeostasis in cancer cells is correlated with sustained cell proliferation and the inhibition of cell death through the modulation of Ca 2+ signaling. This article is part of a Special Issue entitled Mitochondria in Cancer, edited by Giuseppe Gasparre, Rodrigue Rossignol and Pierre Sonveaux. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. The Case of Capogrossi in Rome: Collecting Data with Different Technologies on a Contemporary Mural Painting

    Science.gov (United States)

    Mezzadri, P.; Russo, J.

    2017-05-01

    This paper focuses on the presentation of a part of the main thematic data documenting the pathologies and the degradation problems of a contemporary mural painting, which was designed and carried out by the italian artist Giuseppe Capogrossi in 1954. This forgotten masterpiece is developed on the ceilings of the main double stairscase at the entrance of the Airone, an ex-cinema-theatre in Rome (Italy). In time, the original project was completely damaged and now the Airone cinema is abandoned since 1999; the decoration, strictly connected to the function of the original project, has been completely covered by synthetic coatings. The documentation of the observed pathologies and the original materials of the lower ceiling takes place during a restoration project in 2015-2016 and was accomplished by utilizing different technologies in order to facilitate the collecting of the main data within several graphic thematic tables. The challenge of this documentation was to create a contact point, and perhaps also a contamination, between the practices of CAD graphic documentation, restoration and GIS technology.

  17. Social Cognition in Williams Syndrome: Face Tuning.

    Science.gov (United States)

    Pavlova, Marina A; Heiz, Julie; Sokolov, Alexander N; Barisnikov, Koviljka

    2016-01-01

    Many neurological, neurodevelopmental, neuropsychiatric, and psychosomatic disorders are characterized by impairments in visual social cognition, body language reading, and facial assessment of a social counterpart. Yet a wealth of research indicates that individuals with Williams syndrome exhibit remarkable concern for social stimuli and face fascination. Here individuals with Williams syndrome were presented with a set of Face-n-Food images composed of food ingredients and in different degree resembling a face (slightly bordering on the Giuseppe Arcimboldo style). The primary advantage of these images is that single components do not explicitly trigger face-specific processing, whereas in face images commonly used for investigating face perception (such as photographs or depictions), the mere occurrence of typical cues already implicates face presence. In a spontaneous recognition task, participants were shown a set of images in a predetermined order from the least to most resembling a face. Strikingly, individuals with Williams syndrome exhibited profound deficits in recognition of the Face-n-Food images as a face: they did not report seeing a face on the images, which typically developing controls effortlessly recognized as a face, and gave overall fewer face responses. This suggests atypical face tuning in Williams syndrome. The outcome is discussed in the light of a general pattern of social cognition in Williams syndrome and brain mechanisms underpinning face processing.

  18. Clinical experience and critical evaluation of the role of sorafenib in renal cell carcinoma

    Directory of Open Access Journals (Sweden)

    Zustovich F

    2011-05-01

    Full Text Available Fable Zustovich1, Giuseppe Lombardi1, Davide Pastorelli1, Patrizia Farina1, Massimo Dal Bianco2, Luca De Zorzi2, Maurizia Dalla Palma1, Ornella Nicoletto1, Vittorina Zagonel11Oncologia Medica 1, Istituto Oncologico Veneto-IRCCS, Padova, Italy; 2UO Urologia, Ospedale Sant'Antonio, ULSS 16, Padova, ItalyAbstract: Renal cell carcinoma (RCC is a common malignancy worldwide with approximately 95,000 new cases per year and ranks as the sixth cause of cancer deaths. Until recently, the slightly active and very toxic cytokines were available for patients with advanced RCC. Advances have been made in understanding the molecular biology of renal cancer. The introduction of targeted agents has led to promising possibilities for treating these highly vascularized tumors. Angiogenesis inhibition is likely to represent the main potential therapeutic target. Sorafenib is an oral multikinase inhibitor with activity against tyrosine kinase receptors that are responsible for blood vessel development and has shown to be active in treating advanced RCC. In this review, we summarize the pharmacology, mode of action, pharmacokinetics, and safety of sorafenib use in therapy for advanced RCC.Keywords: sorafenib, pharmacokinetics, angiogenesis 

  19. Storie ‘vere’ ed eroine dei romanzi. Rappresentare la Somalia in 'Ilaria Alpi. La ragazza che voleva raccontare l’inferno' e 'Non dirmi che hai paura'

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    Simone Brioni

    2016-09-01

    Full Text Available ‘True’ Stories and Heroines in Novels: The Representation of Somalia in Ilaria Alpi: The Young Woman Who Wanted to Narrate Hell and Don’t Tell Me You Are AfraidThis article analyses Gigliola Alvisi’s Ilaria Alpi: La ragazza che voleva raccontare l’inferno [Ilaria Alpi: The Young Woman Who Wanted to Narrate the Hell] (2014 and Giuseppe Catozzella’s Non dirmi che hai paura [Don’t Tell Me You Are Afraid] (2014, two novels that deal with two recent events in Somali and Italian history, the killing of the journalist Ilaria Alpi in Mogadishu in 1994 and the death of Samia Yosuf Omar while she was trying to reach the Italian shores from Libya by boat. Alvisi’s text is analysed in comparison with other fictional and journalistic representations of Ilaria Alpi, while Non dirmi che hai paura is examined through what Catozzella considers the two constitutive dimensions of the novel: documentation and identification. Drawing on Stefano Jossa’s reflections on the construction of literary heroes, the article challenges Alvisi’s and Catozzella’s claims that they represent ‘true stories’. The article also argues that the main characters of these literary works are portrayed as heroines and role models for the emancipation of Muslim women.

  20. La acción católica y la política en el Perú: la posición de los prelados peruanos a principios de la década de 1920

    Directory of Open Access Journals (Sweden)

    Jesús Ara Goñi

    2013-04-01

    Full Text Available El objetivo de este artículo es demostrar que, a principios de la dé- cada de 1920, la Iglesia católica peruana concibió la realidad social e implementó su acción mediante la categoría acción católica. Para desarrollar este tema se han analizado diversas fuentes: cartas pastorales, prensa, correspondencia, memorias de asociaciones católicas, y, de forma destacada, la documentación relativa a una encuesta promovida entre los prelados peruanos a fínales de 1921 por el nuncio en Perú, Giuseppe Petrelli. El análisis de dichas fuentes nos permite sostener que la Acción Católica fue clave tanto en la intervención de los católicos en política como en la relación Iglesia-Estado y causa de fractura en el seno de la Iglesia peruana.

  1. I modelli istituzionali di integrazione musulmana in Europa e il caso dell’ “Islám italiano”

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    Salvatore Prisco

    2011-02-01

    Full Text Available Il testo (ultimato il 24 febbraio 2011 fonde - aggiornandoli nella considerazione degli sviluppi successivi alle circostanze che hanno dato occasione alle rispettive trattazioni originarie - i temi svolti durante l’intervento nella tavola rotonda finale sul tema La Carta dei valori della cittadinanza e dell’integrazione (alla quale parteciparono, con chi scrive, Michele Lepri Gallerano, Massimo Papa e Giuseppe Verde, moderatore Raffaele Coppola al Convegno delle Università di Bari e del Salento sul tema Libertà religiosa e Multiculturalismo (Gallipoli, 29 febbraio-1 marzo 2008, i cui Atti sono in corso di pubblicazione nel volume omonimo, a cura di R. Coppola, V. Tondi della Mura, V. Turchi, ESI, Napoli, e nella relazione al Convegno sul tema La tutela dei minori di cultura islamica nell’area mediterranea. Aspetti sociali, giuridici, medici, organizzato dalla Facoltà di Studi arabo-islamici e del Mediterraneo dell’Università L’Orientale (Napoli, 28-29 ottobre 2009, i cui Atti sono anch’essi in via di pubblicazione. Il presente lavoro è destinato alla pubblicazione anche negli Studi in onore di Aldo Lojodice.

  2. Capecitabine-induced cardiotoxicity: more evidence or clinical approaches to protect the patients' heart?

    Directory of Open Access Journals (Sweden)

    Fontanella C

    2014-09-01

    Full Text Available Caterina Fontanella,1 Marianna Aita,1 Marika Cinausero,1 Giuseppe Aprile,1 Maria Grazia Baldin,2 Veronica Dusi,3 Chiara Lestuzzi,4 Gianpiero Fasola,1 Fabio Puglisi1,5 1Department of Oncology, University Hospital of Udine, Udine, Italy; 2Department of Cardiology, Palmanova General Hospital, Palmanova, Italy; 3Department of Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy; 4Department of Cardiology, Centro di Riferimento Oncologico, National Cancer Institute, Aviano, Italy; 5Department of Medical and Biological Sciences, University of Udine, Udine, Italy Abstract: Fluoropyrimidines, such as capecitabine and 5-fluorouracil, may cause cardiac toxicity. In recent years, the incidence of this side effect has increased and it is expected to further rise due to the population aging and the disproportionate incidence of breast and gastrointestinal cancers in older individuals. The spectrum of cardiac manifestations includes different signs and symptoms and the diagnosis may be difficult. Here, we report the case of a 43-year-old woman with advanced breast cancer who was rechallenged with a capecitabine-based regimen after experiencing a cardiac adverse event during the first fluoropyrimidine exposure. This real-practice case serves as a springboard for discussion about the current evidence on differential diagnosis of capecitabine-related cardiac toxicity, its risk factors, and the underpinning mechanisms of early onset. Moreover, we discussed whether a rechallenge with fluoropyrimidines could be safe in patients who had experienced a previous cardiac adverse event. Keywords: risk factors, clinical manifestation, rechallenge

  3. Social cognition in autism: Face tuning.

    Science.gov (United States)

    Pavlova, Marina A; Guerreschi, Michele; Tagliavento, Lucia; Gitti, Filippo; Sokolov, Alexander N; Fallgatter, Andreas J; Fazzi, Elisa

    2017-05-26

    Faces convey valuable information for social cognition, effective interpersonal interaction, and non-verbal communication. Face perception is believed to be atypical in autism, but the origin of this deficit is controversial. Dominant featural face encoding is suggested to be responsible for face tuning scarcity. Here we used a recently developed Face-n-Food paradigm for studying face tuning in individuals with autistic spectrum disorders (ASD). The key benefit of these images is that single components do not explicitly trigger face processing. In a spontaneous recognition task, adolescents with autism and typically developing matched controls were presented with a set of Face-n-Food images in different degree resembling a face (slightly bordering on the Giuseppe Arcimboldo style). The set of images was shown in a predetermined order from the least to most resembling a face. Thresholds for recognition of the Face-n-Food images as a face in ASD individuals were substantially higher than in typically developing controls: they did not report seeing a face on the images, which controls easily recognized as a face, and gave overall fewer face responses. This outcome not only lends support to atypical face tuning, but provides novel insights into the origin of face encoding deficits in autism.

  4. Staff members with 25 years' service at CERN in 2005

    CERN Multimedia

    2005-01-01

    The 74 staff members who have spent 25 years at CERN in 2005 were invited by the Director-General to a reception in their honour on 22 November. ADRIAN Gilbert / AB ALLIOD Marie-Noëlle / AB ANTOINET Gérard / SC AUBERT Marc / TS AUQUIER Christian / SC BAIRD Simon / AB BARRAS Suzanne / PH BAUD Richard / AT BELLONI Jean / SC BERTUOL Gilbert / SC BLANC Jean-Luc / AB BONVALLET Guy / SC BOSSUS Patrice / SC BROERE Johannes / AB BRU Yvon / TS BURDAIRON Alain / TS CANARD Philippe / AT CAVALLO Patrice / SC CHARRA Patrick / PH CHATAIGNEAU Marc / SC COLIN Gilles / SC DAHLEN Pierre / AB DE GROOT Johannes / PH DEDOBBELER Bernard / TS DELCAMBRE Jean Pierre / SC DELENCLOS Yves / TS DEROYER Patrick / SC DESBISSONS Christian / SC DRAPER Mick / AB DROUX Pascal / FI DUCASTEL Claude / TS DUMUR Alain / SC FOCKER Gerrit / AB FOFFANO Giuseppe / TS FORRAT Isabelle / IT FREI Marie-José / DSU FRESSARD Michel / TS GAGNIERE Daniel / TS GIUDICI Pierre-Ange / PH GOICOECHEA Bernard / TS GUEHO Alain / TS GUENEHEC François / SC JE...

  5. The origins of psychology in Italy: Themes and authors that emerge through a content analysis of the Rivista di Filosofia Scientifica [Journal of Scientific Philosophy].

    Science.gov (United States)

    Bartolucci, Chiara; Lombardo, Giovanni Pietro

    2012-08-01

    This article examines the scientific-cultural context of the second half of the 1800s, during which psychological science emerged in Italy. The article explores the contribution made by the emergence of the primary research traditions of that period, namely, physiological anthropology and phreniatry, by means of a methodology that combines content analysis with a classical historiographical study of the period. Themes and authors deriving from the various disciplines in the human and natural sciences were identified through a content analysis of the Rivista di Filosofia Scientifica [Journal of Scientific Philosophy], a periodical that is representative of Italian positivism. The analysis highlights the epistemological perspective held by scholars who, distancing themselves from the mechanistic reductionism of the proponents of positivism, integrated a naturalistic and evolutionary conceptualization with the neo-Kantian critique. A clearly delineated naturalistic and differential perspective of scientific research that brought about the birth of psychology as an experimental discipline in Italy in the 1900s emerges from the analysis, including psychology and psychopathology as studied by the phreniatrists Gabriele Buccola, Enrico Morselli, and Eugenio Tanzi; Tito Vignoli and Giuseppe Sergi's work in comparative anthropology; Giulio Fano's approach and contribution to physiology; and Enrico Ferri's contribution to criminology. (PsycINFO Database Record (c) 2012 APA, all rights reserved).

  6. Ornella Labriola: the loneliness of an irreducible memory

    Directory of Open Access Journals (Sweden)

    Maria Antonietta Selvaggio

    2017-01-01

    (1908-1991, who lived between Italy and Soviet Union. She was a guest of the famous hotel “Lux” in Moscow, the dwelling place of international Communism during the years of Stalinism. In that place, happened her love story with Giuseppe Rimola (1905-1938, delegate of Italian young communists in the Kjm (the Young Communist International. He was arrested and condemned to death as ”people’s enemy” in the gyre concerning he terror of Stalinism. During all her life, Ornella Labriola only desired to show people the truth about the death of her own partner, also to rescue the sense of her own existence and choices. The biographical approach of our research permits to emphasize witness’s feelings, believes, values and auto-reflexivity. Labriola was interviewed a year before her death. Her narration is focused on her relationship with ideology, with the revolutionary time when she grew, with the political treat as it was perceived during the thirties and forties; but also she talked about her love relation with her partner in a cultural context in which it was normal to sacrifice own private life on the altar of revolutionary necessities.

  7. The effects of sulodexide on both clinical and molecular parameters in patients with mixed arterial and venous ulcers of lower limbs

    Directory of Open Access Journals (Sweden)

    Serra R

    2014-05-01

    Full Text Available Raffaele Serra,1,2,* Luca Gallelli,3,* Angela Conti,1 Giovanni De Caridi,4 Mafalda Massara,4 Francesco Spinelli,4 Gianluca Buffone,1 Francesco Giuseppe Caliò,5 Bruno Amato,6 Simona Ceglia,7 Giuseppe Spaziano,8 Luca Scaramuzzino,9 Alessia Giovanna Ferrarese,10 Raffaele Grande,1 Stefano de Franciscis1,2 1Interuniversity Center of Phlebolymphology (CIFL, International Research and Educational Program in Clinical and Experimental Biotechnology, University Magna Graecia of Catanzaro, Catanzaro, Italy; 2Department of Medical and Surgical Sciences, University Magna Graecia of Catanzaro, Catanzaro, Italy; 3Department of Health Sciences, University Magna Graecia of Catanzaro, Catanzaro, Italy; 4Cardiovascular and Thoracic Department, University of Messina, Messina, Italy; 5Unit of Vascular Surgery, S Anna Hospital, Catanzaro, Italy; 6Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy; 7Department of Experimental and Clinical Medicine, University Magna Graecia of Catanzaro, Catanzaro, Italy; 8Department of Experimental Medicine, Second University of Naples, Naples, Italy; 9University Campus BioMedico of Rome, Rome, Italy; 10Department of General Surgery, University of Turin, Turin, Italy *These authors contributed equally to this work Background: Mixed venous and arterial ulcers account for approximately 15%–30% of all venous leg ulcerations. Several studies have shown that matrix metalloproteinases (MMPs and neutrophil gelatinase-associated lipocalin (NGAL play a central role in the pathophysiology of venous and arterial diseases. Some studies have shown the efficacy of glycosaminoglycans, such as sulodexide (SDX, in treating patients with leg ulcers. The aim of this study was to evaluate clinical effects of SDX and its correlation with MMPs and NGAL expression in patients with mixed arterial and venous leg ulcers. Methods: Patients eligible for this study were of both sexes, older than 20 years, and with a

  8. PREFACE: 5th International Workshop on Top Quark Physics (TOP2012)

    Science.gov (United States)

    Salamanna, G.; Boisvert, V.; Cerrito, L.; Khan, A.; Moretti, S.; Owen, M.; Schwanenberger, C.

    2013-07-01

    resonances in the boosted top regime were also provided. Finally, a set of dedicated talks on the interplay between the top sector and other hot subjects, like the Higgs and SUSY, were given both at the theory and experimental level. Furthermore, ad hoc student sessions were organized to allow younger colleagues to pose questions to the senior experts in the field and contribute with their more recent studies. The conference has been a definitive success, not just scientifically: about 130 participants from all over the world created a collegiate spirit which culminated in the social events at Winchester Hall below King Arthur's table; and in a cosy 16th century barn for the social dinner. The Local Organizing Committee would like to thank all participants, and in particular the speakers, for their high level contributions to TOP 2012 and for making this a very fruitful and pleasant time together. We conclude by wishing the Organizing Committee of TOP 2013 all the best for a successful conference. We look forward to seeing everyone in Germany in 2013. Giuseppe Salamanna Local Organizing Committee London, June 2013 Local Organising Committee Veronique Boisvert (Chair, Royal Holloway, University of London) Lucio Cerrito (Queen Mary, University of London) Akram Khan (Brunel University, London) Stefano Moretti (University of Southampton) Mark Owen (University of Manchester) Giuseppe Salamanna (Queen Mary, University of London) Christian Schwanenberger (University of Manchester) International Advisory Committee Roberto Tenchini (INFN, Pisa) Martine Bosman (IFAE, Barcelona) Michelangelo Mangano (CERN) Scott Willenbrock (University of Illinois, Urbana) Werner Bernreuther (RWTH, Aachen) Jorgen D'Hondt (VUB, Brussels) Antonio Onofre (LIP, University Minho) Fabio Maltoni (UCL, Louvain) Eric Laenen (NIKHEF) Fabrizio Margaroli (INFN, Roma 1) Juan Antonio Aguilar Saavedra (University of Granada) Yvonne Peters (University of Manchester) Roberto Chierici (CERN) Markus Cristinziani

  9. Human responses to the 1906 eruption of Vesuvius, southern Italy

    Science.gov (United States)

    Chester, David; Duncan, Angus; Kilburn, Christopher; Sangster, Heather; Solana, Carmen

    2015-04-01

    Cultural and political contexts are important in determining the ways in which communities respond to volcanic eruptions. Understanding the manner in which communities and the State apparatus have coped with historic eruptions can provide insights into how responses have influenced vulnerability and resilience. The 1906 eruption of Vesuvius is well suited for such a study as it was one of the first major eruptions in which there was a significant element of State control, and this worked alongside more traditional pre-industrial responses. This eruption was extensively reported in the regional, national and international press and in archives which include still photography. One feature is the rich archive of material published in English language newspapers of record which are analysed fully in the paper for the first time. Many of these data sources are now accessible on-line. The eruption started on April 4th with mild explosive activity and the eruption of lava from 5th to 7th April. On the night of the 7th/8th, activity intensified when a vigorous lava fountain inclined obliquely to the north east, deposited a thick layer of tephra on the towns of Ottaviano and San Giuseppe. This led to roof collapse and a large number of fatalities. There was increased lava emission and a flow progressed south through the outskirts of Boscotrecase cutting the Circumvesuviana railway line and almost reaching Torre Annunziata. Following April 8th the eruption declined and ended on April 21st. In the initial responses to the eruption pre-industrial features were prominent, with the local communities showing social cohesion, self-reliance and little panic. A more negative aspect was the traditional religious response that involved the use of liturgies of divine appeasement and which included the use of saintly relics and images. There is interesting evidence, however, that this coping strategy was driven by the populace rather than by the clergy. The inhabitants of San Giuseppe

  10. Lorenzo Lotto e gli strumenti del mestiere: la periferia come consapevole scelta strategica / Lorenzo Lotto and the tools of the trade: the periphery as a conscious strategic choice

    Directory of Open Access Journals (Sweden)

    David Frapiccini

    2014-06-01

    Full Text Available Con il testamento del 25 marzo 1531 Lorenzo Lotto stabiliva la ripartizione dei modelli in gesso e in cera e dei propri disegni tra tre suoi antichi allievi: il bergamasco Francesco Bonetti, il veneziano Pietro di Giovanni – in quel momento attivo a Ragusa, l’odierna Dubrovnik – e il marchigiano maestro Giulio da Amandola, identificabile con Giulio Vergari. Dalle provenienze dei tre artefici si manifesta una chiara mappa geografica, come se Lotto avesse consapevolmente deciso di lasciare i ferri del mestiere nei luoghi della sua esperienza pittorica: a Bergamo, a Venezia e nelle Marche. Contemporaneamente Lotto frequenta i pittori Alessandro Oliverio, Bonifacio de’ Pitati da Verona e Girolamo da Santa Croce: il secondo, stando alle disposizioni testamentarie, avrebbe dovuto completare le opere rimaste incompiute alla morte di Lotto, mentre al terzo sarebbero andati alcuni strumenti della professione a beneficio dei propri figli. Si viene così a delineare un gruppo di artisti marginale rispetto al contesto lagunare, ma orientato verso committenze di entroterra o di area adriatica. La consapevolezza acquisita da Lotto nell’incidenza territoriale della sua attività spiega la ragione delle reminiscenze iconografiche e formali bergamasche in parte della produzione risalente agli estremi anni marchigiani (1549-1556, ovvero a quella fase inaugurata con l’Assunzione anconetana di San Francesco alle Scale, pala realizzata nel 1549-1550 con la collaborazione di Giuseppe Belli da Ponteranica. With the will of March 25, 1531 Lorenzo Lotto established the distribution of models in plaster and wax and their designs to three of his former pupils: Francesco Bonetti from Bergamo, the Venetian Pietro di Giovanni – at that time active in Ragusa, today's Dubrovnik – and maestro Giulio from Amandola identified with Giulio Vergari. The origins of the three painters manifest a clear geographical map, as if Lotto had consciously decided to leave the

  11. Ontological Encoding of GeoSciML and INSPIRE geological standard vocabularies and schemas: application to geological mapping

    Science.gov (United States)

    Lombardo, Vincenzo; Piana, Fabrizio; Mimmo, Dario; Fubelli, Giandomenico; Giardino, Marco

    2016-04-01

    SimpleLithology CGI vocabulary and aligned as a subclass of the Substance class in NASA SWEET ontology), and 3) an ontology of the MappedFeatures (as defined in the Representation sub-taxonomy of the NASA SWEET ontology). The latter correspond to the concrete elements of the map, with their geometry (polygons, lines) and geographical coordinates. The ontology model has been developed by taking into account applications primarily concerning the needs of geological mapping; nevertheless, the model is general enough to be applied to other contexts. In particular, we show how the automatic reasoning capabilities of the ontology system can be employed in tasks of unit definition and input filling of the map database and for supporting geologists in thematic re-classification of the map instances (e.g. for coloring tasks). ---------------------------------------- [1] http://www.geosciml.org [2] http://inspire.jrc.ec.europa.eu/documents/Data_Specifications/INSPIRE_DataSpecification_GE_v3.0rc3.pdf [3] http://www.cgi-iugs.org/tech_collaboration/geoscience_terminology_working_group.html [4] https://www.seegrid.csiro.au/subversion/CGI_CDTGVocabulary/trunk/OwlWork/CGI_Lithology.owl [5] We are currently neglecting the encoding of the geologic events, left as a future work. [6] http://resource.geosciml.org/vocabulary/cgi/201211/ [7] Web site: https://sweet.jpl.nasa.gov, Di Giuseppe et al., 2013, SWEET ontology coverage for earth system sciences, http://www.ics.uci.edu/~ndigiuse/Nicholas_DiGiuseppe/Research_files/digiuseppe14.pdf; S. Barahmand et al. 2009, A Survey on SWEET Ontologies and their Applications, http://www-scf.usc.edu/~taheriya/reports/csci586-report.pdf

  12. Tolerability and camouflaging effect of corrective make-up for acne: results of a clinical study of a novel face compact cream

    Directory of Open Access Journals (Sweden)

    Monfrecola G

    2016-10-01

    Full Text Available Giuseppe Monfrecola, Sara Cacciapuoti, Claudia Capasso, Mario Delfino, Gabriella Fabbrocini Department of Clinical Medicine and Surgery, Section of Dermatology, University of Naples Federico II, Naples, Italy Background: A novel face compact cream (FCC containing a new patented formulation was recently developed to provide acne patients with cosmetic camouflage for their lesions and to have beneficial effects on the multifactorial components of the disease. This pilot investigation aimed to evaluate the real-life tolerability, potential for comedogenicity and covering effect provided by this FCC.Methods: This single-center study evaluated the FCC applied once daily for 28 days in 20 females with facial acne. Tolerability was assessed by rating skin reactions on a scale from 1 =absent to 4 =evident. Comedogenicity potential was evaluated by determining the number of facial acne lesions before and after use of the FCC. The covering effect was rated in ten patients 30 minutes after application on a scale from 1 =none to 5 =excellent. Patients rated their opinions on the FCC on day 28 using a questionnaire.Results: Assessment of tolerability on days 0, 14, and 28 showed that skin reactions, including erythema, edema, dryness, desquamation, tight feeling, itching, and burning, were absent in all patients. The FCC was noncomedogenic and provided a significant 15.8% reduction in facial acne lesions after 28 days (P<0.001. The FCC provided a good covering effect 30 minutes after application in 80% of patients. All patients (100% were satisfied with the FCC, with 90% agreeing that the FCC was effective and 80% stating that the FCC improved their skin.Conclusion: The FCC was positively perceived, well tolerated, noncomedogenic, and provided an effective covering of acne in this small group of female patients with 1 month of follow-up. Keywords: acne, comedones, dermatocosmetic, tolerability

  13. Psychological resources, satisfaction, and career identity in the work transition: an outlook on Sicilian college students

    Directory of Open Access Journals (Sweden)

    Santisi G

    2018-05-01

    Full Text Available Giuseppe Santisi,1 Paola Magnano,2 Silvia Platania,1 Tiziana Ramaci2 1Department of Educational Sciences, University of Catania, Catania, Italy; 2Faculty of Human and Social Sciences, “Kore” University of Enna, Enna, Italy Background: The phases of career building today bring out a more complex process than in previous decades. Starting from the literature review, the university-to-work transition is considered a very important step in the future career of the graduates, and it involves some psychological resources and requires specific abilities. Methods: Research has examined the psychological resources that students at the end of a degree course can use in the university-to-work transition. The aim of the study is to verify the relationship between academic satisfaction and career identity, and the mediational role of readiness and confidence on this relationship. A group of 438 students were assigned to complete a questionnaire in order to examine the relationship between academic satisfaction and career identity and the role of core components of psychological resources: readiness and confidence as mediator. Results: The results indicated both a direct relationship between academic satisfaction and career identity and a mediated relationship with the influence of readiness and confidence for a transition. Adding to our results, we assert that academic satisfaction has a directed effect on confidence during the transition and is a predictor of career identity, both directly and by the mediation of readiness in career transitions. Conclusion: Career identity has implication for exploratory behavior, thus increasing the motivation and mindfulness that create a virtuous circle, influencing the development of knowledge and skills, which are the base of proactivity and confidence in construction of one’s future career. Keywords: career, transition, identity, satisfaction, resources

  14. Management strategies in the treatment of neonatal and pediatric gastroenteritis

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    Ciccarelli S

    2013-10-01

    Full Text Available Simona Ciccarelli,1 Ilaria Stolfi,1 Giuseppe Caramia2 1Neonatal Intensive Care Unit, Sapienza University of Rome, Rome, Italy; 2Division of Neonatology and Pediatrics, Maternal and Child Hospital "G. Salesi", Ancona, Italy Abstract: Acute gastroenteritis, characterized by the onset of diarrhea with or without vomiting, continues to be a major cause of morbidity and mortality in children in mostly resource-constrained nations. Although generally a mild and self-limiting disease, gastroenteritis is one of the most common causes of hospitalization and is associated with a substantial disease burden. Worldwide, up to 40% of children aged less than 5 years with diarrhea are hospitalized with rotavirus. Also, some microorganisms have been found predominantly in resource-constrained nations, including Shigella spp, Vibrio cholerae, and the protozoan infections. Prevention remains essential, and the rotavirus vaccines have demonstrated good safety and efficacy profiles in large clinical trials. Because dehydration is the major complication associated with gastroenteritis, appropriate fluid management (oral or intravenous is an effective and safe strategy for rehydration. Continuation of breastfeeding is strongly recommended. New treatments such as antiemetics (ondansetron, some antidiarrheal agents (racecadotril, and chemotherapeutic agents are often proposed, but not yet universally recommended. Probiotics, also known as “food supplement,” seem to improve intestinal microbial balance, reducing the duration and the severity of acute infectious diarrhea. The European Society for Paediatric Gastroenterology, Hepatology and Nutrition and the European Society of Paediatric Infectious Diseases guidelines make a stronger recommendation for the use of probiotics for the management of acute gastroenteritis, particularly those with documented efficacy such as Lactobacillus rhamnosus GG, Lactobacillus reuteri, and Saccharomyces boulardii. To date, the

  15. Large-spot subthreshold transpupillary thermotherapy for chronic serous macular detachment

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    Giuseppe Lo Giudice

    2011-03-01

    Full Text Available Giuseppe Lo Giudice1, Valentina de Belvis2, Marco Tavolato1, Alessandro Galan11San Paolo Ophthalmic Center, San Antonio Hospital, Padova, Italy; 2Paediatric Low Vision Center, Paediatric Rare Eye Disease Center, Department of Paediatrics, University of Padova, ItalyPurpose: To report the effect of subthreshold transpupillary thermotherapy (TTT in treating serous detachment of the neurosensory retina secondary to chronic central serous chorioretinopathy (CCSC.Methods: Seven eyes from five patients with CCSC, persistent serous detachment of the neurosensory retina and a clinical course of between 12 and 60 months were treated. All eyes received large-spot TTT guided by indocyanine green angiography (ICGA. Subthreshold TTT was performed using an 810 nm diode laser with a spot size of 3.0 mm (power was set at 350 mW. Treatment was applied for 60 seconds to the areas of choroidal hyperfluorescence on ICGA.Results: The mean number of TTT sessions was 1.4 ± 0.5. All eyes were followed up for at least 6 months (mean 9.6 ± 3.2 standard deviation; range 6–12 months. The mean logarithm of the minimum angle of resolution best-corrected visual acuity was significantly better compared with baseline. All TTT-treated eyes had stable or improved vision (P < 0.001. Mean optical coherence tomography (OCT central foveal thickness was significantly lower in all patients (P < 0.001 compared with pretreatment OCT, with a reduction in subretinal fluid and resolution of serous detachment associated with anatomical fovea restoration. No patient had any treatment-related side effects.Conclusion: Modified subthreshold TTT appears to have a beneficial effect in treating patients with CCSC and persistent neurosensory detachment. The encouraging results and lack of visually significant complications suggest that further investigation is warranted.Keywords: central serous chorioretinopathy, indocyanine green angiography, neurosensory detachment, transpupillary

  16. PhD Dissertations

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    Redazione Reti Medievali (a cura di

    2005-12-01

    Tra Riforma, vescovo e clientes. Camaldoli e le società locali (secoli XI-XIII, Tesi di dottorato di ricerca in Storia medievale, Università degli studi di Firenze, 2005 [09/05] Giuseppe Gardoni "Episcopus et potestas". Vescovi e società a Mantova nella prima metà del Duecento, Tesi di dottorato di ricerca in Storia del Cristianesimo e delle Chiese (antichità, medioevo, età moderna, Università degli Studi di Padova, 2005 Nicola Mancassola La gestione delle campagne tra Langobardia e Romània in età carolingia e post carolingia. La struttura delle aziende fondiarie in Emilia e Romagna, Tesi di dottorato in Storia Medievale, Università degli Studi di Bologna, 2005 Gloria Papaccio Storia e archeologia degli opifici idraulici in Val di Pesa. La Badia di Passignano e i suoi mulini (XI-XIV secolo, Tesi di dottorato di ricerca in Storia medievale, Università degli studi di Firenze, 2005 Adelaide Ricci La città e il suo ospedale: assetti urbani, dinamiche sociali e organizzazione del sistema caritativo-assistenziale a Cremona nel XV secolo, Tesi di dottorato di ricerca in Storia Medievale, Università degli studi di Torino, 2005 Luca Sant'Ambrogio Il borgo di Treviglio nel secondo Quattrocento: istituzioni e società, Tesi di dottorato di ricerca in Storia Medievale, Università degli Studi di Milano, 2005 Elisabetta Scarton Giovanni Lanfredini. Uomo d'affari e diplomatico nell'Italia del Quattrocento, Tesi di dottorato in Storia della società europea, Università degli Studi di Napoli "Federico II", 2005

  17. Language, visuality, and the body. On the return of discourse in contemporary performance

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    Vangelis Athanassopoulos

    2013-12-01

    Full Text Available This article deals with the return of discourse in experimental performance-based artistic practices. By putting this return in a historical perspective, we wish to address the questions it raises on the relation between language, image, and the body, resituating the avant-garde heritage in a contemporary context where intermediality and transdisciplinarity tend to become the norm rather than the exception. The discussion of the status and function of discourse in this context calls on the field of theatre and its ambivalent role in modern aesthetics, both as a specifically determined artistic discipline, and as a blending of heterogeneous elements, which defy the assigned limitations of creative practice. The confrontation of Antonin Artaud's writings with Michael Fried's conception of theatricality aims to bring to the fore the cultural transformations and historical paradoxes which inform the shift from theatre to performance as an experimental field situated “between” the arts and embracing a wide range of practices, from visual arts to music and dance. The case of lecture-performance enables us to call attention to the internal contradictions of the “educational” interpretation of such experimental practices and their autonomization inside the limits of a specific artistic genre. The main argument is that, despite the plurality of its origins and its claims to intermediality and transdisciplinarity, lecture-performance as a genre is attracted by or gravitates around the extended field of the visual arts. By focusing on the work of Jerôme Bel, Noé Soulier, Giuseppe Chico, Barbara Matijevic, and Carole Douillard, we stress some of the ways contemporary discursive strategies enable to displace visual spectacle toward a conception of the body as the limit of signification.

  18. Managing diabetic patients with moderate or severe renal impairment using DPP-4 inhibitors: focus on vildagliptin

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    Russo E

    2013-04-01

    Full Text Available Eleonora Russo, Giuseppe Penno, Stefano Del Prato Department of Clinical and Experimental Medicine, Section of Diabetes and Metabolic Disease, Azienda Ospedaliero Universitaria di Pisa, and University of Pisa, Pisa, Italy Background: Dipeptidyl peptidase-4 (DPP-4 inhibitors are novel classified oral anti-diabetic drugs for the treatment of type 2 diabetes mellitus (T2DM that provide important reduction in glycated hemoglobin, with a low risk for hypoglycemia and no weight gain. In T2DM patients with reduced renal function, adequate glycemic control is essential to delay the progress of kidney dysfunction, but they are at a greater risk of experiencing hypoglycemic events, especially with longer-acting sulfonylureas and meglitinides. Objective: To evaluate vildagliptin as an option to achieve glycemic control in T2DM patients with moderate or severe chronic kidney disease (CKD. Methods: A comprehensive search in the literature was performed using the term "vildagliptin." Original articles and reviews exploring our topic were carefully selected. Results: Vildagliptin provides effective glycemic control in patients with T2DM and CKD. Dose reductions are required for vildagliptin and other DPP-4 inhibitors, except linagliptin, in T2DM patients with moderate-to-severe CKD. Dose of vildagliptin had to be reduced by half (to 50 mg/day both for moderate (estimated glomerular filtration rate [eGFR] ≥30 to ≤50 mL/min and severe CKD (eGFR < 30 mL/min. Available results support a favorable efficacy, safety, and tolerability profile for vildagliptin in T2DM with moderate or severe renal failure. Preliminary data may suggest additional benefits beyond improvement of glycemic control. Conclusion: Vildagliptin can be safely used in T2DM patients with varying degrees of renal impairment. Dose adjustments for renal impairment are required. Potential long-term renal benefit of vildagliptin needs to be further explored. Keywords: type 2 diabetes mellitus, renal

  19. DCLK1 immunoreactivity in colorectal neoplasia

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    Bellows CF

    2012-04-01

    Full Text Available Giuseppe Gagliardi1, Monica Goswami1, Roberto Passera2, Charles F Bellows11Department of Surgery and Pathology, Tulane University, New Orleans, LA, USA; 2Division of Nuclear Medicine Azienda Ospedaliero-Universitaria San Giovanni Battista, Turin, ItalyIntroduction: Microtubule-associated doublecortin and CaM kinase-like-1 (DCLK1 is a novel candidate marker for intestinal stem cells. The aim of our study was to assess DCLK1 immunoreactivity in colorectal carcinogenesis and its correlation with prognosis.Methods: DCLK1 immunostaining was performed in colorectal tissue from 71 patients, including 18 adenomatous polyps, 40 primary adenocarcinomas, and 14 metastatic lesions. Each case was evaluated by a combined scoring method based on the intensity of staining (score 0–3 and the percentage of tissue staining positive (score 0–3. Immunoexpression for DCLK1 was considered as positive when the combined score was 2–6 and negative with a score of 0–1.Results: Overall, 14/18 (78% of polyps, 30/40 (75% of primary adenocarcinomas, and 7/14 (50% of distant metastases were positive for DCLK1. In adenomatous polyps and primary cancer there was no association between DCLK1 staining score and tumor pathology. However, after curative colorectal cancer resection, patients whose tumor had a high (≥5 combined staining score had increased cancer-specific mortality compared to patients with low (0–4 staining score (hazard ratio 5.89; 95% confidence interval: 1.22–28.47; P = 0.027.Conclusion: We found that DCLK1 is frequently expressed in colorectal neoplasia and may be associated with poor prognosis. Further studies are necessary to validate the use of DCLK1 as a prognostic marker.Keywords: DCLK1, DCAMKL-1, gastrointestinal stem cell, cancer stem cell, adenomatous polyps, liver metastasis, immunohistochemistry

  20. Combining Experiments and Simulations of Extraction Kinetics and Thermodynamics in Advanced Separation Processes for Used Nuclear Fuel

    Energy Technology Data Exchange (ETDEWEB)

    Nilsson, Mikael

    2018-05-15

    This 3-year project was a collaboration between University of California Irvine (UC Irvine), Pacific Northwest National Laboratory (PNNL), Idaho National Laboratory (INL), Argonne National Laboratory (ANL) and with an international collaborator at ForschungZentrum Jülich (FZJ). The project was led from UC Irvine under the direction of Profs. Mikael Nilsson and Hung Nguyen. The leads at PNNL, INL, ANL and FZJ were Dr. Liem Dang, Dr. Peter Zalupski, Dr. Nathaniel Hoyt and Dr. Giuseppe Modolo, respectively. Involved in this project at UC Irvine were three full time PhD graduate students, Tro Babikian, Ted Yoo, and Quynh Vo, and one MS student, Alba Font Bosch. The overall objective of this project was to study how the kinetics and thermodynamics of metal ion extraction can be described by molecular dynamic (MD) simulations and how the simulations can be validated by experimental data. Furthermore, the project includes the applied separation by testing the extraction systems in a single stage annular centrifugal contactor and coupling the experimental data with computational fluid dynamic (CFD) simulations. Specific objectives of the proposed research were: 1. Study and establish a rigorous connection between MD simulations based on polarizable force fields and extraction thermodynamic and kinetic data. 2. Compare and validate CFD simulations of extraction processes for An/Ln separation using different sizes (and types) of annular centrifugal contactors. 3. Provide a theoretical/simulation and experimental base for scale-up of batch-wise extraction to continuous contactors. We approached objective 1 and 2 in parallel. For objective 1 we started by studying a well established extraction system with a relatively simple extraction mechanism, namely tributyl phosphate. What we found was that well optimized simulations can inform experiments and new information on TBP behavior was presented in this project, as well be discussed below. The second objective proved a larger

  1. European Uunion Energy Security and Russia

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    Nodari A. Simonia

    2015-01-01

    Full Text Available The article deals with the retrospective of relations between Russia, USA and EU in the sphere of energy security, as well as their interaction regarding the current political crisis in the Ukraine. Particular attention is paid to the evolution of the key actors'positions and the development of their relations within the framework of the regulatory regimes established by the most significant agreements in the energy sphere. In conclusion the authors claim that what they say in their article not only does substantially reinforce the arguments set forth by Professor Giuseppe Guarino, who argues about the negative consequences caused by the dictatorship of the Brussels's bureaucracy within the EU, but also inflicts another blow on the Maastricht Treaty and the Treaty of Lisbon in terms of external policy and trade, since the both Treaties were designed to convert the EU in a real competitor of the United States in the then forming multipolar World. The Brussel's bureaucracy, having turned into a dutiful instrument of the US geopolitical strategy, hindered the movement of the EU in that direction, while its dictatorship in energy security aggravates the crisis situation of the EU, almost pushing the EU to the brink of collapse and disintegration. We have lately witnessed an evolving and growing phenomenon of the so called "Euroscepticism". The results of the Europarliament elections in late May, 2014, were a graphic demonstration of the symptoms of this alarming for the EU disease, when the anti-EU parties in the four out 22 EU countries won the elections (France, United Kingdom, Denmark, and Greece Those results, regardless of the panic headlines in mass media and statements like "shocking" or "earthquake" made by some politicians, were not able to significantly affect the nature of the European Parliament, though they can significantly complicate its work. This is so far the first "alarming bell" tolling for the EU.

  2. The museum setup in the Benedictine dormitory of Monreale: the artworks of Santa Maria del Bosco and the textile artefacts of the Cathedral, Sicily, Italy

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    Maria Concetta di Natale

    2018-03-01

    Full Text Available The recent decision to convert the Benedictine Dormitory in Monreale into an exhibition site offers the opportunity to enjoy the whole monumental complex where the wonderful cloister is the core attraction. It is on this site that the Norman Cathedral stands, brightly decorated with golden mosaics. The new exhibition has gathered together the artworks from the ruined abbey of Santa Maria del Bosco in Calatamauro and added them to the artefacts already exhibited at the Diocesan Museum. They include marble gravestones from the 16th-17th century church and those dating to the 18th century; one stone is in polychrome marble of the family of the canons, Candes and Donato; another was used for the burial of the monks from the period of the Olivetan refoundation, characterized by the Order’s coat of arms and attributed to Girolamo Musca. There are also majolica tiles from the chapels in cornu evangelij (left side of the altar adorned with large vegetal-shaped decorations, provided by Palermitan manufacturers in the mid-eighteenth century. They are found next to the remnants of the majolica tiles still in situ, executed in 1762 by the potters from Burgio, in Sicily. Rosario Rosso (also Russo and Giuseppe Virgadamo. Also commissioned after the refoundation of the holy temple are the four artworks by the painter Ippolito Ferrante, three of which, Sacrificio di Isacco, Melchisedec and Giale e Sisar, are on exhibition in the prestigious museum. Alongside these artworks are noteworthy textile artefacts made between the second half of the 16th and second half of the 18th centuries some of which are linked to the munificent figures of archbishops such as Ludovico II Torres and Francesco Testa.

  3. The Italian decommissioning industry

    International Nuclear Information System (INIS)

    Adinolfi, R.

    2005-01-01

    Full text: Italy's step out from nuclear activities in 1987 deeply affected an industry that, in the previous years, had managed to grow up in quality and technology levels to meet the nuclear standards. Only a few companies were able to partially retain their skills through activities abroad. The decommissioning program represents a new challenge for the Italian industry at large and will require a consistent effort to properly qualify the potential suppliers. On the other side, a program with such implications in terms of investments and so depending from social aspects cannot be effectively implemented without a significant involvement of the local industry. Essential conditions for the success are a reliable program, as well as a careful supply management scheme, which must facilitate aggregation of skills spread among different subjects. 'Human Resources: Maintaining a Nuclear Culture in Italy' Bruno Panella Politecnico di Torino, Giuseppe Forasassi, Universita di Pisa, Inter-University Consortium for the Nuclear Technological Research (CIRTEN). After a brief history of the nuclear engineering education in Italy within the international and national nuclear energy scenario, the present situation, with reference to the Italian universities, is shown. In order to maintain a nuclear culture in Italy the solution, exploited with different peculiarities in each University, is to carry out high quality research activities in reciprocal collaboration (mostly within the CIRTEN inter university Consortium) as well as with the Industry and research Organisations and to collaborate actively in establishing a stable network and a synergy of teaching activities in Europe in the field of Nuclear Engineering Education. The aim is to maintain at a high level and as updated as possible the Italian educational offer in nuclear engineering and also to attract the best students for the enrolment. (author)

  4. Oltar Sv. Jeronima u crkvi Sv. Šime u Zadru i radionica Bettamelli

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    Bojan Goja

    2012-12-01

    Full Text Available U radu se na temelju arhivskih podataka govori o oltaru Sv. Jeronima u crkvi Sv. Šime u Zadru. Od ranije se zna da je oltar dala podići i o njegovu se uređenju brinula bratovština hrvatskih i albanskih vojnika (Croatti a cavallo i Soldati Albanesi u službi Mletačke Republike, osnovana 1675. godine u Zadru. Novim je arhivskim istraživanjima utvrđeno da je dana 26. rujna 1694. godine bratovština odobrila izdatak u iznosu od 200 srebrnih dukata, namijenjenih venecijanskim klesarima braći Bettamelli kao predujam za izradu oltara te da su radovi na njegovu podizanju započeti u travnju 1696. godine. Na temelju zapisa o gradnji oltara iznijeta je pretpostavka da se grb na istočnom pilastru stipesa oltara, ranije povezivan s predstavnicima obitelji Civran, odnosi na zadarskog plemića i istaknutog zapovjednika u mletačkoj vojsci, Šimuna Fanfognu (Zadar, 7. travnja 1663. - Lendinara, 6. ožujka 1707. koji je obavljao i dužnost prokuratora oltara. Brojni radovi na uređenju oltara i kapele Sv. Jeronima obavljani su i tijekom čitavog 18. stoljeća, a na njima su bili uposleni brojni mjesni majstori različitih struka: graditelji Antonio Piovesana (1742. i Antonio Bernardini (1789., oltarist Girolamo Picco (1756., marangon Domenico Tomaselli (1743., kovač Antonelli (1744. te zlatari Zorzi Cullisich (1738., Nicolò Giurovich (1752. i Giuseppe Rado (1755.. Donose se još neke zanimljivosti vezane uz uređenje oltara i djelovanje bratovštine Sv. Jeronima.

  5. Women’s Activism and Innovation in Education: the Role of the Unione Femminile Nazionale in Sicily for the Transformation of Italian Pedagogy at the Beginning of the Twentieth Century

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    Letterio Todaro

    2017-01-01

    Full Text Available The beginning of the twentieth century represented a special occasion in the development of women’s movements as a vehicle for a new culture of education. The growing role of women’s associations in modern society found fertile ground in the increasing demand for childcare. In Italy such a process reflected a meaningful phenomenon of social transformation, which was linked to the ascent of the lower classes and to the progression of democratic values. In a region like Sicily, the appearance of local branches of the Unione Femminile Nazionale in some principal cities of the isle, such as Catania, from 1909 onwards represented a crucial opportunity not only for the social and cultural elevation of working-class children, but also for the introduction of new models of schooling and the experimentation of new methods in education, within the wider framework of a general renewal in the science of education of the time. The most representative witness and «learner» of these innovative approaches to education was Giuseppe Lombardo Radice, who was to «transfer» many aspects of his experience into the reform of the entire primary school system in Italy (1923 in line with the design of «active schooling». A survey of the experience of the Sicilian sections of the Unione provides not only a significant example of civilization processes promoted by women’s activism, but also a key to better understanding the wealth of resources involved in the construction of a modern pedagogy in Italy before the coming of Fascism.

  6. First-line targeted therapies in the treatment of metastatic colorectal cancer – role of cetuximab

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    Giuseppe Tonini

    2009-04-01

    Full Text Available Giuseppe Tonini, Alice Calvieri, Bruno Vincenzi, Daniele SantiniMedical Oncology, University Campus Bio-Medico, Rome, ItalyAbstract: Worldwide, colorectal cancer (CRC is the fourth most commonly diagnosed malignant disease and the second leading cause of cancer-related death in Western nations. In 2008 there were an estimated 148,810 new cases and 49,960 deaths in the US. For several years different chemotherapeutic regimens, based on floropyrimidines, irinotecan and oxaliplatin, have been used in advanced CRC, but survival is still unsatisfactory. New targeted therapies, including drugs and monoclonal antibodies (MoABs , show great promise in the fight against CRC and have shown activity in different disease settings. Cetuximab, a chimeric IgG1 monoclonal antibody that binds to the extracellular domain of epidermal growth factor receptor (EGFR, is active in metastatic colorectal cancer (mCRC. As an IgG1 antibody, cetuximab may exert its antitumor efficacy through both EGFR antagonism and antibody-dependent cell-mediated cytotoxicity. The combination of this drug with classical chemotherapies has shown better clinical profiles reflected in an improvement in overall and progression-free survival. Clinical trials established the role of cetuximab, particularly with irinotecan, in irinotecan-refractory/heavily pretreated patients. Whereas cetuximab has a clear indication in the salvage setting, its role in first-line therapy remains investigational. It is particularly encouraging that cetuximab may enhance curative opportunities in patients with early metastatic disease, suggesting that adding cetuximab in first-line therapy may downstage disease in some patients, and, as a result, allow potentially curative resection of previously unresectable metastases. In this review we will focus on the main epidermal growth factor receptor inhibitors demonstrating clinical benefit, and the role of cetuximab in first-line treatment of metastatic CRC

  7. From the history of the recognitions of the remains to the reconstruction of the face of Dante Alighieri by means of techniques of virtual reality and forensic anthropology

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    Stefano Benazzi

    2007-07-01

    Full Text Available The work consists of the reconstruction of the face of the great poet called Dante Alighieri through a multidisciplinary approach that matches traditional techniques (manual ones, usually used in forensic anthropology, with digital methodologies that take advantage of technologies born in manufacturer-military fields but that are more and more often applied to the field of the cultural heritage. Unable to get the original skull of Dante, the work started from the data and the elements collected by Fabio Frassetto and Giuseppe Sergi, two important anthropologists, respectively at the University of Bologna and Rome, in an investigation carried out in 1921, sixth century anniversary of his death, on the remains of the poet collected in Ravenna. Thanks to this, we have a very accurate description of Dante’s bones, including 297 metric data inherent to the whole skeleton, some photographs in the scale of the skull, the various norms and many other bones, as well as a model of the skull subsequently realized by Frassetto. According to these information, a geometric reconstruction of Dante Alighieri skull including the jaw was carried out through the employment and integration of the instruments and technologies of the virtual reality, and from this the relative physical model through fast prototype was realized. An important aspect of the work regards in a particular manner the methodology of 3D modelling proposed for the new reconstruction of the jaw (not found in the course of the 1921 recognition, starting from a reference model. The model of the skull prototype is then useful as the basis for the successive stage of facial reconstruction through the traditional techniques of forensic art.

  8. Clinical features and imaging findings in a case of Capgras syndrome

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    Luca M

    2013-08-01

    Full Text Available Maria Luca,1 Andrea Bordone,1 Antonina Luca,2 Andrea Patti,1 Giuseppe Sortino,3 Carmela Calandra11Department of Medical and Surgery Specialties, Psychiatry Unit, 2Department GF Ingrassia, Section of Neuroscience, 3Department of Diagnostic Imaging, Radiology Unit, University Hospital Policlinico-Vittorio Emanuele, Catania, Sicily, ItalyAbstract: Capgras syndrome consists of the delusional belief that a person or persons have been replaced by doubles or impostors. It can occur in the context of both psychiatric and organic illness, and seems to be related to lesions of the bifrontal and right limbic and temporal regions. Indeed, magnetic resonance imaging has revealed brain lesions in patients suffering from Capgras syndrome. This case study reports the findings of a thorough diagnostic evaluation in a woman suffering from Capgras syndrome and presenting with the following clinical peculiarities: obsessive modality of presentation of the delusional ideation, intrusiveness of such ideation (that even disturbed her sleep, as well as a sense of alienation and utter disgust towards the double. These characteristics bring to mind the typical aspects of obsessive-compulsive disorder. Neuroanatomic investigation, through magnetic resonance imaging, performed on this patient showed alteration of the bilateral semioval centers, which are brain regions associated with the emotion of disgust and often show alterations in subjects suffering from obsessive-compulsive disorder. Hence, neuroimaging allows researchers to put forward the hypothesis of a common neuroanatomic basis for Capgras syndrome and obsessive-compulsive disorder, at least for cases in which the delusional ideation is associated with deep feelings of disgust and presents with a certain pervasiveness.Keywords: Capgras syndrome, magnetic resonance imaging, electroencephalography, obsessive-compulsive disorder, semioval centers

  9. Trieste has no cultural tradition

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    Scipio Slataper

    2018-01-01

    Full Text Available Los artículos de Scipio Slataper (Trieste, 1888 – Monte Calvario, 1915, aparecidos originariamente en La Voce de Giuseppe Prezzolini y más tarde reunidos con el título de Lettere triestine, convirtieron a su autor en uno de los más agudos críticos de las teorías irredentistas italianas. Ejemplo de ello es este artículo publicado el 11 de febrero de 1909, “Trieste non ha tradizioni di cultura”, en el que Slataper ataca de forma directa lo que consideraba el talón de Aquiles de la idea del irredentismo juliano, la falta de una tradición cultural de la ciudad juliana, justamente uno de los pilares en los que burguesía más exaltada basaba su italianidad. La fuerte animadversión que provocaron sus textos periodísticos no evitó que tres años más tarde, en 1912, tras la publicación de su única novela, Il mio Carso, se convirtiera en una de las figuras prominentes de la generación triestina anterior a la guerra. Pese a su posición contraria a la mistificación ideológica irredentista, se alistó como voluntario en el ejército italiano y combatió en el frente de Gorizia, donde encontró la muerte a los veintiséis años.

  10. Comparative pharmacokinetic and pharmacodynamic evaluation of branded and generic formulations of meloxicam in healthy male volunteers

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    Del Tacca M

    2013-07-01

    Full Text Available Mario Del Tacca,1,2 Giuseppe Pasqualetti,3 Giovanni Gori,1 Pasquale Pepe,1 Antonello Di Paolo,2 Marianna Lastella,2 Ferdinando De Negri,1 Corrado Blandizzi2 1Clinical Pharmacology Centre for Drug Experimentation, Pisa University Hospital, 2Department of Clinical and Experimental Medicine, 3Geriatrics Unit, University of Pisa, Pisa, Italy Purpose: The primary aim of the present study was to assess the pharmacokinetic bioequivalence between a generic formulation of meloxicam 15 mg tablets (Meloxicam Hexal and its respective brand product (Mobic, in order to verify whether the generic product conforms to the regulatory standards of bioequivalence in the postmarketing setting. As a secondary exploratory aim, the pharmacodynamic effects of the two formulations were also evaluated by means of rating scales following hyperalgesia induced by cutaneous freeze injury. Subjects and methods: A single 15 mg dose of generic or branded meloxicam tablets was administered to 24 healthy male volunteers in a crossover fashion. Plasma samples, collected for 24 hours after dosing, were assayed for meloxicam concentration by a validated high-performance liquid chromatography method. Results: The analysis of pharmacokinetic parameters did not show any significant difference between the two meloxicam formulations: the 90% confidence intervals fell within the acceptance range of 80%–125% (0.84–1.16 for area under the curve [0–24], and 0.89–1.23 for peak concentration. No difference in the pharmacodynamic end point was observed between the two groups. Conclusion: The pharmacokinetic profiles of the two meloxicam formulations confirm the regulatory criteria for bioequivalence; pharmacodynamic data indicate a similar antihyperalgesic effect. The two formulations can be used interchangeably in the clinical setting. Keywords: meloxicam, pharmacokinetics, healthy volunteers, generic drug, bioequivalence, postmarketing

  11. The ASI science program

    Science.gov (United States)

    Musso, Carlo

    2002-03-01

    Italy came in the space business in 1963, being the third nation in the world, after the Soviet Union and the United States, to put an artificial satellite into orbit. In 1988 the Italian Space Agency (ASI) was constituted, with the mandate of planning, coordinating and executing civil space activities in Italy. The core of national space activities is science, for which Italy spends about 25% of the ASI budget, both in national and international programs. The community served by the scientific directorate of ASI is a very wide one, ranging from the science of the Universe and the exploration of the Solar System to life sciences, from Earth observation to the development of new technologies. The success of Italian space research appears under many different points of view. The national satellite BeppoSAX, named after Giuseppe Beppo Occhialini, widely contributed to solve the γ-ray burst puzzle, obtaining the relevant acknowledgment of the ``Bruno Rossi Prize''. Italian researchers kept the PI-ship of various payloads on board ESA missions, such as Epic for XMM-Newton, Ibis for Integral, Virtis and Giada for Rosetta, PFS and Marsis for Mars Express. Also in the field of the cosmic microwave background (CMB) two important experiments are foreseen in the next future, with Italian PIs: SPOrt on board the International Space Station, dedicated to the polarization of CMB, and LFI (Low Frequency Instrument) on board the ESA Planck satellite, to study CMB anisotropy. Meanwhile, a great success has been obtained with the balloon experiment Boomerang. Moreover, ASI started a national scientific and technological small mission program. The first three missions are on their way: Agile (a γ-ray observatory), David (an experiment to test very high frequency data transmission), and a third one, devoted to Earth science. .

  12. New options in the management of tendinopathy

    Directory of Open Access Journals (Sweden)

    Nicola Maffulli

    2010-03-01

    Full Text Available Nicola Maffulli1, Umile Giuseppe Longo2, Mattia Loppini2, Filippo Spiezia2, Vincenzo Denaro21Centre for Sports and Exercise Medicine, Queen Mary University of London, Barts and The London School of Medicine and Dentistry, Mile End Hospital, London, England; 2Department of Orthopedic and Trauma Surgery, Campus Biomedico University, Rome, ItalyAbstract: Tendon injuries can be acute or chronic, and caused by intrinsic or extrinsic factors, either alone or in combination. Tendinopathies are a common cause of disability in occupational medicine and account for a substantial proportion of overuse injuries in sports. Tendinopathy is essentially a failed healing response, with haphazard proliferation of tenocytes, abnormalities in tenocytes, with disruption of collagen fibres and subsequent increase in noncollagenous matrix. The scientific evidence base for managing tendinopathies is limited. What may appear clinically as an “acute tendinopathy” is actually a well advanced failure of a chronic healing response in which there is neither histologic nor biochemical evidence of inflammation. In this review we report the new options for the management of tendinopathy, including eccentric exercises, extracorporeal shockwave therapy, injections (intratendinous injections of corticosteroids, aprotinin, polidocanol platelet-rich plasma, autologous blood injection, high-volume injections and surgery. Open surgery aims to excise fibrotic adhesions, remove areas of failed healing and make multiple longitudinal incisions in the tendon to detect intratendinous lesions, and to restore vascularity and possibly stimulate the remaining viable cells to initiate cell matrix response and healing. New surgical techniques aim to disrupt the abnormal neoinnervation to interfere with the pain sensation caused by tendinopathy. These procedures are intrinsically different from the classical ones in present use, because they do not attempt to address directly the pathologic

  13. A comparison of wood density between classical Cremonese and modern violins.

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    Berend C Stoel

    Full Text Available Classical violins created by Cremonese masters, such as Antonio Stradivari and Giuseppe Guarneri Del Gesu, have become the benchmark to which the sound of all violins are compared in terms of their abilities of expressiveness and projection. By general consensus, no luthier since that time has been able to replicate the sound quality of these classical instruments. The vibration and sound radiation characteristics of a violin are determined by an instrument's geometry and the material properties of the wood. New test methods allow the non-destructive examination of one of the key material properties, the wood density, at the growth ring level of detail. The densities of five classical and eight modern violins were compared, using computed tomography and specially developed image-processing software. No significant differences were found between the median densities of the modern and the antique violins, however the density difference between wood grains of early and late growth was significantly smaller in the classical Cremonese violins compared with modern violins, in both the top (Spruce and back (Maple plates (p = 0.028 and 0.008, respectively. The mean density differential (SE of the top plates of the modern and classical violins was 274 (26.6 and 183 (11.7 gram/liter. For the back plates, the values were 128 (2.6 and 115 (2.0 gram/liter. These differences in density differentials may reflect similar changes in stiffness distributions, which could directly impact vibrational efficacy or indirectly modify sound radiation via altered damping characteristics. Either of these mechanisms may help explain the acoustical differences between the classical and modern violins.

  14. Ulipristal acetate: a novel pharmacological approach for the treatment of uterine fibroids

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    Biglia N

    2014-02-01

    Full Text Available Nicoletta Biglia,1 Silvestro Carinelli,2 Antonio Maiorana,3 Marta D'Alonzo,1 Giuseppe Lo Monte,4 Roberto Marci4 1Department of Obstetrics and Gynaecology, Mauriziano "Umberto I" Hospital, University of Turin, Turin, 2Department of Pathology, European Institute of Oncology, Milan, 3Department of Obstetrics and Gynecology, ARNAS Civico Hospital, Palermo, 4Department of Morphology, Surgery and Experimental Medicine, Section of Obstetrics and Gynecology, Infertility Unit, University of Ferrara, Ferrara, Italy Abstract: Uterine fibroids are the most common benign tumors of the female genital tract. The management of symptomatic fibroids has traditionally been surgical; however, alternative pharmacological approaches have been proposed to control symptoms. To date, gonadotropin-releasing hormone analogs are the only available drugs for the preoperative treatment of fibroids. However, the US Food and Drug Administration recently authorized ulipristal acetate (UPA, an oral selective progesterone-receptor modulator, for the same indication. UPA is a new, effective, and well-tolerated option for the preoperative treatment of moderate and severe symptoms of uterine fibroids in women of reproductive age. According to clinical data, UPA shows several advantages: it is faster than leuprolide in reducing the fibroid-associated bleeding, it significantly improves hemoglobin and hematocrit levels in anemic patients, and it grants a significant reduction in the size of fibroids, which lasts for at least 6 months after the end of the treatment. Furthermore, UPA displays a better tolerability profile when compared to leuprolide; in fact, it keeps estradiol levels at mid follicular phase range, thereby reducing the incidence of hot flushes and exerting no impact on bone turnover. On the grounds of this evidence, the administration of 5 mg/day ulipristal acetate for 3 months is suggested for different patient categories and allows for planning a treatment strategy

  15. Potential drug–drug interactions in Alzheimer patients with behavioral symptoms

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    Pasqualetti G

    2015-09-01

    Full Text Available Giuseppe Pasqualetti, Sara Tognini, Valeria Calsolaro, Antonio Polini, Fabio Monzani Geriatrics Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy Abstract: The use of multi drug regimens among the elderly population has increased tremendously over the last decade although the benefits of medications are always accompanied by potential harm, even when prescribed at recommended doses. The elderly populations are particularly at an increased risk of adverse drug reactions considering comorbidity, poly-therapy, physiological changes affecting the pharmacokinetics and pharmacodynamics of many drugs and, in some cases, poor compliance due to cognitive impairment and/or depression. In this setting, drug–drug interaction may represent a serious and even life-threatening clinical condition. Moreover, the inability to distinguish drug-induced symptoms from a definitive medical diagnosis often results in addition of yet another drug to treat the symptoms, which in turn increases drug–drug interactions. Cognitive enhancers, including acetylcholinesterase inhibitors and memantine, are the most widely prescribed agents for Alzheimer’s disease (AD patients. Behavioral and psychological symptoms of dementia, including psychotic symptoms and behavioral disorders, represent noncognitive disturbances frequently observed in AD patients. Antipsychotic drugs are at high risk of adverse events, even at modest doses, and may interfere with the progression of cognitive impairment and interact with several drugs including anti-arrhythmics and acetylcholinesterase inhibitors. Other medications often used in AD patients are represented by anxiolytic, like benzodiazepine, or antidepressant agents. These agents also might interfere with other concomitant drugs through both pharmacokinetic and pharmacodynamic mechanisms. In this review we focus on the most frequent drug–drug interactions, potentially harmful, in AD patients with

  16. The melatonergic system: effects on sleep and implications for the treatment of psychiatric disorders

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    De Berardis D

    2011-12-01

    Full Text Available Domenico De Berardis1,2, Tiziano Acciavatti1, Giuseppe Di Iorio1, Mariangela Corbo1, Nicola Serroni2, Daniela Campanella2, Fabiola Di Emidio2, Monica Piersanti3, Marilde Cavuto4, Giovanni Martinotti5, Francesco Saverio Moschetta2, Massimo Di Giannantonio11Department of Neurosciences and Imaging, Chair of Psychiatry, University “G. D'Annunzio”, Chieti; 2NHS, Department of Mental Health, Psychiatric Service of Diagnosis and Treatment, Hospital “G. Mazzini”; 3NHS, Pharmaceutical Service, Hospital “G. Mazzini”, Teramo; 4IASM, L'Aquila; 5Institute of Psychiatry, Catholic University Medical School, Rome, ItalyAbstract: The circadian pacemaker or biological clock, located in the hypothalamic suprachiasmatic nucleus, is the generation site of circadian rhythms. The light/dark cycle is the circadian pacemaker's dominant synchronizing agent, though it is also influenced by neurotransmitters and the phase-shifting effects of various chemical and pharmacological components, of which melatonin (N-acetyl-5-methoxytryptamine is the most well established. In recent years, melatonin and melatonin analogs have been commercialized in many countries, mainly with hypnotic purposes. A new compound, agomelatine, has been recently synthesized and studied. Among melatonin analogs, this drug possesses unique pharmacological and clinical features; it is an antagonist at 5-HT2B and 5-HT2C receptors and has well established antidepressant and anxiolytic properties. Agomelatine opens new perspectives in the chronobiotic treatment of depression. The purpose of the present review was to elucidate the effects of the melatonergic system on sleep and the implications for the treatment of psychiatric disorders.Keywords: melatonin, agomelatine, circadian rhythms, depression

  17. [Italy of miracles. Does the renaissaince of Italian science pass by the Vatican?].

    Science.gov (United States)

    Naldi, Luigi

    2016-03-01

    In a commentary published in The Lancet on January 2016, Giuseppe Remuzzi and Richard Horton, analyse the origin of the decline of the Italian primacy in biomedical science. Among the others, the existence of Italian political groups «which oppose science simply to please the Church and to achieve political gain» was considered as detrimental for advancing research in such areas as assisted reproduction or embryonic stem cell research. Some hope for a change is raised, in the opinion of Remuzzi and Horton, by the more open attitude toward science of pope Francis. Hence, the two authors conclude that the time has come to promote a dialogue between Italian scientists and the Vatican and, by that, to see «if conditions are ripe to create a renaissance in Italian intellectual life». I humbly challange the analyses and conclusions of Remuzzi and Horton on the Italian scientific decline and the possible way forward. The rooth of the Italian decline in science are deep-seated into the chronic lack of resources, into the under-development of academic institutions, and into the lack of motivations for young researchers. As for bioethical paradigms, they are the end result of a co-production between social norms and scientific development, and their definition would ideally involve the participation of large sectors of the society. One example of such a process is offered by the "Les Etats généraux de la bioéthique" in France in 2009. The ethical discussion concerning biotech innovations is not limited to theological issues, but involves social aspects such as public health priorities, equity, and information strategies to avoid creating unrealistic expectations.

  18. Risk of Essure microinsert abdominal migration: case report and review of literature

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    Ricci G

    2014-11-01

    Full Text Available Giuseppe Ricci,1,2 Stefano Restaino,2 Giovanni Di Lorenzo,1 Francesco Fanfani,1 Federica Scrimin,1 Francesco P Mangino1 1Institute for Maternal and Child Health, IRCCS “Burlo Garofolo”, Trieste, Italy; 2Department of Medical Sciences, University of Trieste, Trieste, Italy Purpose: To report a case of Essure microinsert abdominal migration and literature review.Methods: A 41-year-old woman was counseled to undergo Essure sterilization. The procedure was hampered by the presence of endometrial cavity adhesions, obscuring left tubal ostium. By using microscissors the adhesions were progressively lysed. Since the procedure had become very painful, the patient required general anesthesia. Once adhesion lysis was completed, the tubal ostium was well visible. Both devices were then easily introduced into the fallopian tubes. At the end of the procedure, five coils were visible on the right side and five coils on the left side, as recommended.Results: The 3-month hysterosalpingogram follow-up suspected abdominal migration of the left device. Laparoscopy confirmed the device displacement in the left lower abdominal quadrant. Both fallopian tubes and the uterus appeared normal. No signs of perforation were detected. The device was embedded into the omentum, but it was easily removed. Bilateral tubal sterilization was performed by bipolar coagulation.Conclusion: There are only 13 cases, including the present, of Essure abdominal migration in the literature. In most cases, abdominal displacement of the microinsert is asymptomatic and does not induce tissue damage. However, in some cases, it may cause a severe adverse event, requiring major surgery. Therefore, removal of the migrated device should be performed as soon as possible. Moreover, during presterilization counseling, the patient should also be correctly informed about the risk of this rare but relevant complication, as well as about the surgical interventions that could be required to solve it

  19. Labeling and exocytosis of secretory compartments in RBL mastocytes by polystyrene and mesoporous silica nanoparticles

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    Ekkapongpisit M

    2012-04-01

    Full Text Available Maneerat Ekkapongpisit1,*, Antonino Giovia1,*, Giuseppina Nicotra1, Matteo Ozzano1, Giuseppe Caputo2,3, Ciro Isidoro1 1Laboratory of Molecular Pathology and Nanobioimaging, Department of Health Sciences, Università del Piemonte Orientale "A. Avogadro", Novara, Italy; 2Department of Chemistry, University of Turin, Turin, 3Cyanine Technology SpA, Torino, Italy *These authors contributed equally to this workBackground: For a safe ‘in vivo’ biomedical utilization of nanoparticles, it is essential to assess not only biocompatibility, but also the potential to trigger unwanted side effects at both cellular and tissue levels. Mastocytes (cells having secretory granules containing cytokines, vasoactive amine, and proteases play a pivotal role in the immune and inflammatory responses against exogenous toxins. Mastocytes are also recruited in the tumor stroma and are involved in tumor vascularization and growth.Aim and methods: In this work, mastocyte-like rat basophilic leukemia (RBL cells were used to investigate whether carboxyl-modified 30 nm polystyrene (PS nanoparticles (NPs and naked mesoporous silica (MPS 10 nm NPs are able to label the secretory inflammatory granules, and possibly induce exocytosis of these granules. Uptake, cellular retention and localization of fluorescent NPs were analyzed by cytofluorometry and microscope imaging.Results: Our findings were that: (1 secretory granules of mastocytes are accessible by NPs via endocytosis; (2 PS and MPS silica NPs label two distinct subpopulations of inflammatory granules in RBL mastocytes; and (3 PS NPs induce calcium-dependent exocytosis of inflammatory granules.Conclusion: These findings highlight the value of NPs for live imaging of inflammatory processes, and also have important implications for the clinical use of PS-based NPs, due to their potential to trigger the unwanted activation of mastocytes.Keywords: secretory lysosomes, inflammation, nanoparticles, vesicular traffic

  20. Modeling the structure of the attitudes and belief scale 2 using CFA and bifactor approaches: Toward the development of an abbreviated version.

    Science.gov (United States)

    Hyland, Philip; Shevlin, Mark; Adamson, Gary; Boduszek, Daniel

    2014-01-01

    The Attitudes and Belief Scale-2 (ABS-2: DiGiuseppe, Leaf, Exner, & Robin, 1988. The development of a measure of rational/irrational thinking. Paper presented at the World Congress of Behavior Therapy, Edinburg, Scotland.) is a 72-item self-report measure of evaluative rational and irrational beliefs widely used in Rational Emotive Behavior Therapy research contexts. However, little psychometric evidence exists regarding the measure's underlying factor structure. Furthermore, given the length of the ABS-2 there is a need for an abbreviated version that can be administered when there are time demands on the researcher, such as in clinical settings. This study sought to examine a series of theoretical models hypothesized to represent the latent structure of the ABS-2 within an alternative models framework using traditional confirmatory factor analysis as well as utilizing a bifactor modeling approach. Furthermore, this study also sought to develop a psychometrically sound abbreviated version of the ABS-2. Three hundred and thirteen (N = 313) active emergency service personnel completed the ABS-2. Results indicated that for each model, the application of bifactor modeling procedures improved model fit statistics, and a novel eight-factor intercorrelated solution was identified as the best fitting model of the ABS-2. However, the observed fit indices failed to satisfy commonly accepted standards. A 24-item abbreviated version was thus constructed and an intercorrelated eight-factor solution yielded satisfactory model fit statistics. Current results support the use of a bifactor modeling approach to determining the factor structure of the ABS-2. Furthermore, results provide empirical support for the psychometric properties of the newly developed abbreviated version.

  1. A very rare case of HPV-53-related cervical cancer, in a 79-year-old woman with a previous history of negative Pap cytology

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    Zappacosta R

    2014-04-01

    Full Text Available Roberta Zappacosta,1 Giuseppe Lattanzio,2 Patrizia Viola,2 Manuel Maria Ianieri,3 Daniela Maria Pia Gatta,1 Sandra Rosini11Cytopathology Unit, Experimental and Clinical Sciences Department, Gabriele d’Annunzio University of Chieti-Pescara, Chieti, Italy; 2Surgical Pathology Unit, 3Obstetrics and Gynecology Unit, SS Annunziata Hospital, Chieti, ItalyAbstract: The introduction of organized cervical cancer (CC screening programs has drastically reduced the prevalence of CC. However the incidence is still too high, especially among elderly women. All guidelines strongly recommend a regular Papanicolaou (Pap testing for young and middle-aged patients. On the other hand, many international professional societies no longer advise screening in women who have undergone hysterectomy, and in women aged 65 years and above, who have a previous history of regular Pap smears. Here we report the case of poorly differentiated CC, involving the pelvic lymph nodes and urinary bladder, occurring in a 79-year-old woman who regularly underwent Pap tests, with no reported cytological abnormalities. In this very rare case, the CC cells, as well as cells from metastatic lymph nodes and cells from urinary specimens, molecularly showed human papilloma virus (HPV-53. With the limitations of a single case, this report brings important information to prevent CC in elderly patients: the utility of molecular tests to increase sensitivity of Pap smears in postmenopausal women; the importance of HPV-53 as one of the four “emergent” genotypes having a possible role in oncogenesis; and the presence of HPV-53 in lymph node metastases from cervical carcinoma, which would support the role of this virus in the maintenance of malignant status.Keywords: old women, molecular tests, cervical cancer screening, HPV-DNA test, HPV genotypingA Letter to the editor has been received and published for this articleCorrigendum for this paper has been published

  2. Red wine and cardiovascular health the "French Paradox" revisited

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    Giuseppe Lippi

    2010-01-01

    Full Text Available Giuseppe Lippi1, Massimo Franchini2, Gian Cesare Guidi31U.O. di Diagnostica Ematochimica, 2Servizio di Immunoematologia e Trasfusione, Dipartimento di Patologia e Medicina di Laboratorio, Azienda Ospedaliero, Universitaria di Parma, Parma, Italy; 3Sezione di Chimica Clinica, Dipartimento di Scienze Morfologico-Biomediche, Università degli Studi di Verona, Verona, ItalyAbstract: The healthful and nutritive properties of wine have been acknowledged for thousands of years, but the observation that moderate consumption of red wine on a regular basis may be preventative against coronary disease is recent. Dr Renaud, a scientist working at the Bordeaux University in France, suggested wine consumption explains the “French Paradox”, the low incidence of heart attacks in France regardless of a remarkable dietary intake of saturated fats and alcohol. After nearly 20 years of research, there is now mounting evidence that light to moderate wine intake is beneficial for the cardiovascular health, acting through a variety of mechanisms that target all the crucial steps of atherosclerosis, from early formation of the atherosclerotic plaque to its life-threatening complications (ulceration, thrombosis, vessel occlusion and infarction. These effects are attributable to the synergic properties of several biochemical components of wine (alcohol, resveratrol, and especially polyphenolic compounds, particularly the red varieties. This article reviews the leading clinical observations and the hypothesized biological mechanisms that strongly support the cardiovascular benefits of moderate red wine consumption on cardiovascular health and that would make red wine a promising therapeutic supplement to prevent and even perhaps treat coronary artery disease.Keywords: wine, cardiovascular disease, coronary disease, atherosclerosis

  3. Italian neuropsychology in the second half of the twentieth century.

    Science.gov (United States)

    Vallar, Giuseppe; Boller, François; Grossi, Dario; Gainotti, Guido

    2015-03-01

    Since the early 1960s, human neuropsychology, the study of brain-behavior interrelations, mainly based on the analysis of their pathological variations, brought about by brain damage, has had a remarkable systematical development in Italy. All this started in Milan, with the neurologist Ennio de Renzi, and his collaborators (Luigi Vignolo, then Anna Basso, Pietro Faglioni, Hans Spinnler, François Boller, and, more autonomously, Edoardo Bisiach), in the Clinic of Nervous and Mental Diseases. Scientists of the "Milan group" investigated several neuropsychological deficits caused by focal hemispheric lesions in large series of left- and right-brain-damaged patients, and control participants, comparable for cultural and demographic variables. Standardized tests and advanced statistical methods were used, which also applied to the diagnosis and rehabilitation of aphasia. Subsequently, neuropsychology developed in Italy extensively, reaching high international reputation. Leading neuropsychologists have been the neurologists Guido Gainotti (Rome), and Franco Denes (Padua), the physicians and psychologists Luigi Pizzamiglio (Rome), and Carlo Umiltà (Parma, with fruitful interactions with the neurophysiologists Giovanni Berlucchi, Giacomo Rizzolatti, and Carlo Marzi, from the school of Giuseppe Moruzzi in Pisa) A second scientific generation of neuropsychologists has then developed in the 1970s, trained by the abovementioned scientists, further boosting and spreading high-level basic and applied research (diagnosis and rehabilitation of neuropsychological deficits of patients with brain damage or dysfunction throughout the life span, from childhood to the elderly). Available techniques include structural and functional imaging (CT, PET, SPET, MRI and fMRI Scans, DTI), electrophysiological recording (EEG, ERPs), non-invasive brain stimulation (TMS, tES), and their combined use.

  4. Energy in Italy: Problems and perspectives (1990-2020)

    International Nuclear Information System (INIS)

    Bassani, G.F.; Bianucci, M.; Carra, S.; Cifarelli, L.

    2009-01-01

    Given the importance and up-to-dateness of the subject, the Italian Physical Society-SIF has decided to reprint its White Book, Energy in Italy: problems and perspectives (1990-2020), as a special issue of Il Nuovo Cimento B. This issue is in honour of the late SIF President Giuseppe Franco Bassani, to recall his leading role in establishing a very active and authoritative Sif Energy Commission, bringing together a number of distinguished experts in the various fields. The Sif Energy Commission was able to produce this White Book, as a comprehensive study on the subject, in just one year time. It was successfully presented at the international meeting on Energy perspectives in Europe, jointly organized by the European Physical Society (Eps) and Sif. The meeting was held in Varenna, Italy, on 7-8 April 2008: it was the second of a series that eventually led to the creation in 2010 of a dedicated Eps Energy Group, budded from the existing Eps Technology Group. First printed in Italian, the White Book was than translated into English and widely circulated within the Eps. It can be downloaded in open access from the SIF web site (http://www.sif.it). In its present updated version, it is made available to the readers of Il Nuovo Cimento B. Last but not least, the White Book has inspired the so-called Energy at School set of booklets targeting Italian high-school teachers and pupils, that will shortly appear as addenda to the Sif journal Giornale di Fisica and will be freely distributed both in paper and electronic versions.

  5. Gradenigo Syndrome: Unusual Consequence of Otitis Media

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    Jennie M. Valles

    2014-07-01

    Full Text Available Introduction: In 1904, Giuseppe Gradenigo published his case series on the triad of ipsilateral abducens nerve palsy, facial pain in the trigeminal nerve distribution, and suppurative otitis media, which would subsequently be referred to as Gradenigo syndrome. Case Report: Our patient was a 36-year-old female, 23 weeks pregnant, with a 6-day history of right-sided otalgia and hearing loss and a 4-day history of purulent otorrhea, who presented with severe, holocephalic headache, meningeal signs, fever, photophobia, and mental status decline. Lumbar puncture yielded a white blood cell count of 1,559 cells/mm3 with 95% polymorphonuclear leukocytes, a red blood cell count of 111 cells/mm3, a protein level of 61 mg/dl, and a glucose level of Streptococcus pneumoniae and treated with ceftriaxone. On the second hospital day, she developed horizontal diplopia due to right abducens nerve palsy and right mydriasis. Both symptoms resolved on the third hospital day. Erosion of temporal bone and opacification of mastoid air cells was shown on CT scan. A CT venogram showed an irregularity of the left transverse and superior sagittal sinuses. She was treated with enoxaparin for possible sinus thrombosis. Discussion: This case demonstrates rare but serious sequelae of otitis media and Gradenigo syndrome. Holocephalic headache from meningitis masked trigeminal pain. Involvement of the ipsilateral petrous apex and surrounding structures on imaging and clinical improvement with antibiotic treatment supports Gradenigo syndrome over intracranial hypertension due to venous sinus thrombosis as the cause of the abducens nerve palsy.

  6. The extension of Rome׳s Capitoline Museums and the design of a new Hall on the site of the ancient ‘Giardino Romano’

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    Raffaele Panella

    2015-09-01

    Full Text Available The new Hall of Marcus Aurelius in the Capitoline Museums, located within the ancient site of Giardino Romano, displays the original statue of the Roman emperor of the 2nd century AD. The idea of extending the Capitoline Museums by including this site came about in the framework of its general redevelopment.11 The chronology of the design work stretches from 1993 to 2002; the works have been achieved between 2004 and 2005. The design leader was Carlo Aymonino and his collaborators architects Maria Luisa Tugnoli, Geneviève Hanssen, Raffaella Castrignanò. The structural design is by engineer Antonio Michetti, with Giuseppe Silvetti and architect Marco Astolfi. The new Hall is the result of a long and complicated process (1988–2005 considering the exceptional importance of the site and the many changes brought to the museum programme during the said period (Figures 1 and 2.In fact, the new Hall was originally supposed to display the marbles of the Temple of Apollo Sosianus, the foundation wall of the Temple of Capitoline Jupiter, embedded within the structures of the Palazzo Caffarelli, opposite the Giardino Romano. However, in 1997, the plan for the Capitoline Museum changed radically as the statue of Marcus Aurelius, which had been restored following the blast of a bomb attack in 1979, was determined to be the focus of the Hall. The project finally consisted of a steel and glass structure on an elliptic plan andshaped around the foundations of the Temple, with the statue at its center.

  7. Osteogenic response of human mesenchymal stem cells to well-defined nanoscale topography in vitro

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    de Peppo GM

    2014-05-01

    Full Text Available Giuseppe Maria de Peppo,1–3 Hossein Agheli,2,3 Camilla Karlsson,2,3 Karin Ekström,2,3 Helena Brisby,3,4 Maria Lennerås,2,3 Stefan Gustafsson,3,5 Peter Sjövall,3,5,6 Anna Johansson,2,3 Eva Olsson,3,5 Jukka Lausmaa,3,6 Peter Thomsen,2,3 Sarunas Petronis3,6 1The New York Stem Cell Foundation Research Institute, New York, NY, USA; 2Department of Biomaterials, Sahlgrenska Academy, University of Gothenburg, 3BIOMATCELL VINN Excellence Center of Biomaterials and Cell Therapy, 4Department of Orthopaedics, Sahlgrenska Academy, University of Gothenburg, 5Applied Physics, Chalmers University of Technology, Göteborg, Sweden; 6Chemistry, Materials and Surfaces, SP Technical Research Institute of Sweden, Borås, Sweden Background: Patterning medical devices at the nanoscale level enables the manipulation of cell behavior and tissue regeneration, with topographic features recognized as playing a significant role in the osseointegration of implantable devices. Methods: In this study, we assessed the ability of titanium-coated hemisphere-like topographic nanostructures of different sizes (approximately 50, 100, and 200 nm to influence the morphology, proliferation, and osteogenic differentiation of human mesenchymal stem cells (hMSCs. Results: We found that the proliferation and osteogenic differentiation of hMSCs was influenced by the size of the underlying structures, suggesting that size variations in topographic features at the nanoscale level, independently of chemistry, can be exploited to control hMSC behavior in a size-dependent fashion. Conclusion: Our studies demonstrate that colloidal lithography, in combination with coating technologies, can be exploited to investigate the cell response to well defined nanoscale topography and to develop next-generation surfaces that guide tissue regeneration and promote implant integration. Keywords: colloidal lithography, nanotopography, human mesenchymal stem cells, cell proliferation, osteogenic

  8. Cortical spreading depression produces a neuroprotective effect activating mitochondrial uncoupling protein-5

    Directory of Open Access Journals (Sweden)

    Viggiano E

    2016-07-01

    Full Text Available Emanuela Viggiano,1,2 Vincenzo Monda,1 Antonietta Messina,1 Fiorenzo Moscatelli,3 Anna Valenzano,3 Domenico Tafuri,4 Giuseppe Cibelli,3 Bruno De Luca,1 Giovanni Messina,1,3 Marcellino Monda1 1Department of Experimental Medicine, Section of Human Physiology and Unit of Dietetics and Sports Medicine, Second University of Naples, Naples, 2Department of Medicine, University of Padua, Padua, 3Department of Clinical and Experimental Medicine, University of Foggia, Foggia, 4Department of Motor Sciences and Wellness, University of Naples “Parthenope”, Naples, Italy Abstract: Depression of electrocorticogram propagating over the cortex surface results in cortical spreading depression (CSD, which is probably related to the pathophysiology of stroke, epilepsy, and migraine. However, preconditioning with CSD produces neuroprotection to subsequent ischemic episodes. Such effects require the expression or activation of several genes, including neuroprotective ones. Recently, it has been demonstrated that the expression of the uncoupling proteins (UCPs 2 and 5 is amplified during brain ischemia and their expression exerts a long-term effect upon neuron protection. To evaluate the neuroprotective consequence of CSD, the expression of UCP-5 in the brain cortex was measured following CSD induction. CSD was evoked in four samples of rats, which were sacrificed after 2 hours, 4 hours, 6 hours, and 24 hours. Western blot analyses were carried out to measure UCP-5 concentrations in the prefrontal cortices of both hemispheres, and immunohistochemistry was performed to determine the localization of UCP-5 in the brain cortex. The results showed a significant elevation in UCP-5 expression at 24 hours in all cortical strata. Moreover, UCP-5 was triggered by CSD, indicating that UCP-5 production can have a neuroprotective effect. Keywords: cortical spreading depression, neuroprotective effect, uncoupling protein-5

  9. Echographic detectability of optoacoustic signals from low-concentration PEG-coated gold nanorods

    Directory of Open Access Journals (Sweden)

    Conversano F

    2012-08-01

    Full Text Available Francesco Conversano,1 Giulia Soloperto,1 Antonio Greco,1 Andrea Ragusa,1,2 Ernesto Casciaro,1 Fernanda Chiriacò,1 Christian Demitri,3 Giuseppe Gigli,2–5 Alfonso Maffezzoli,3 Sergio Casciaro11National Research Council, Institute of Clinical Physiology, Lecce, Italy; 2National Nanotechnology Laboratory of CNR-NANO, Lecce, Italy; 3University of Salento, Department of Engineering for Innovation, Lecce, Italy; 4Italian Institute of Technology – Center for Biomolecular Nanotechnology (CBN-IIT, Arnesano, Italy; 5University of Salento, Department of Mathematics and Physics ‘Ennio De Giorgi’, Lecce, ItalyPurpose: To evaluate the diagnostic performance of gold nanorod (GNR-enhanced optoacoustic imaging employing a conventional echographic device and to determine the most effective operative configuration in order to assure optoacoustic effectiveness, nanoparticle stability, and imaging procedure safety.Methods: The most suitable laser parameters were experimentally determined in order to assure nanoparticle stability during the optoacoustic imaging procedures. The selected configuration was then applied to a novel tissue-mimicking phantom, in which GNR solutions covering a wide range of low concentrations (25–200 pM and different sample volumes (50–200 µL were exposed to pulsed laser irradiation. GNR-emitted optoacoustic signals were acquired either by a couple of single-element ultrasound probes or by an echographic transducer. Off-line analysis included: (a quantitative evaluation of the relationships between GNR concentration, sample volume, phantom geometry, and amplitude of optoacoustic signals propagating along different directions; (b echographic detection of “optoacoustic spots,” analyzing their intensity, spatial distribution, and clinical exploitability. MTT measurements performed on two different cell lines were also used to quantify biocompatibility of the synthesized GNRs in the adopted doses.Results: Laser irradiation at

  10. An historic discovery around the corner from school: Ceres, a solar system object with an uncertain identity.

    Science.gov (United States)

    Stira, Salvatore

    2016-04-01

    Ceres is the largest object in the asteroid belt between Mars and Jupiter, and it was discovered on January 1, 1801, by the Italian astronomer Giuseppe Piazzi. The study of Ceres is especially relevant to my students because this celestial body was discovered in Palermo, in the astronomic observatory located in the UNESCO world heritage site "Palazzo dei Normanni", around 500 meters away from the institute where I teach, and because Ceres was considered the patron goddess of Sicily. Moreover, it received scientists and media attention recently because it was explored by the NASA Dawn spacecraft in 2015. The categorization of Ceres has changed more than once and has been the subject of some disagreement. It was originally considered a planet, but was reclassified as an asteroid in the 1850s when many other objects in similar orbits were discovered. Its status changed again in 2006 when it was promoted to dwarf planet, a classification it shares with Pluto and other Kuiper belt objects. The study of this celestial body has a notable educational value, since the uncertain identity of Ceres constitutes an occasion to reflect on the criterions of classification of the natural objects. The history of its discovery allows the students to understand as the scientific method doesn't always consist in the verification of hypothesis through experiments but it sometimes asks for the forecast of facts through mathematical calculations, repeated and methodic observations, the collaboration between scientists of different sectors and nationality. Furthermore, it is a particularly suitable topic for interdisciplinary connections, as regards both scientific and humanistic matters. In order to promote the scientific competences of my first class students, I have developed a learning unit on Ceres, thanks to good cooperation with the Palermo Observatory scientists, particularly active in the astronomic dissemination towards the schools and the citizens. The most meaningful activities

  11. The influence of parenting on maladaptive cognitive schema: a cross-sectional research on a group of adults

    Directory of Open Access Journals (Sweden)

    Pellerone M

    2017-02-01

    Full Text Available Monica Pellerone,1 Calogero Iacolino,1 Giuseppe Mannino,2 Ivan Formica,3 Simona Maria Zabbara1 1Faculty of Human and Social Sciences, “Kore” University of Enna, Enna, Sicily, Italy; 2Department of Jurisprudence, “LUMSA” University, Rome, Italy; 3Department of Cognitive, Psychological, Pedagogical Sciences and Cultural Studies, University of Study of Messina, Messina, Sicily, Italy Background: The literature emphasizes the role of early interpersonal experiences in the development of cognitive vulnerability; in particular, interruptions in early family relationships, parental unavailability and dysfunctional parenting are potential evolutionary precursors to negative cognitive style and emotional disorders.Materials and methods: This study measured the relationship of retrospective ratings on parental bonding with cognitive patterns in a group of Italian adults. The objectives of this study were as follows: to analyze the influence of age and education level on cognitive domains; to verify whether being parents and living at home with parents affect both parenting style and cognitive domains; to investigate how the type of the maternal and paternal parenting independently affects cognitive styles; to measure the predictive variables for the use of cognitive dysfunctional patterns and to investigate age as a moderating variable of the relation between parenting styles and cognitive domains in a group of adult men and women. The research involved 209 adults (118 males and 91 females living in Sicily (Italy aged between 20 and 60 years (M = 37.52; SD = 11.42. The research lasted for 1 year. The instruments used were the Parental Bonding Instrument to measure the perception of parenting during childhood and the Young Schema Questionnaire-3 to investigate cognitive patterns.Results: Data show that being a younger adult male with mother’s parenting style characterized by a lower level of nurturance is predictive of the disconnection and

  12. Orientalismi all’origine dell’architettura veneziana

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    Fontana, Vincenzo

    2012-07-01

    Full Text Available Between 1964 and 1968 Carlo Scarpa designs the small, precious «patio» of the Fondazione Que- rini Stampalia, in which both Mondrian and Mies van de Rohe, and ancient China and Japan, as well as Venice and the Alhambra, are finally re-read through modern eyes. An orientalist reading of the origins of Venetian architecture is exposed by Leopoldo Cicognara in «Le fabbriche più cospicue di Venezia» (1815-1820 in a posi- tive and appreciative way. The works of Pietro Selvatico similarly show his adherence to both the romantic and the positivist movements: he had been a student of Giuseppe Iappelli, who in the Moorish greenhouse of the gardens of Villa Torlonia in Rome in 1840 translated into architectural form some engravings of Murphy’s Alhambra. The apse of the Murano cathedral in his «Sulla architettura e sulla scultura in Venezia dal Medioevo» (1847 becomes extremely important for John Ruskin. Indeed, through a much deeper analysis of this work, it is seen to become for Ruskin the key of Venetian ornament law until the early Renaissance architecture. Ruskin lays down this law of ornament scientifically and poetically: it is made not only of geometric lines and colors, but of matter and patinas. Thus, Venice offers a pattern to contemporary Victorian architecture and to the future «organic architecture». Camillo Boito traces the Christian character of Murano’s architecture back to its Byzantine and Lombard origins, and compares it with Syrian, Armenian and Coptic churches illustrated by Melchior de Vogüe in «Syrie Central» (1865-1872. These in turn influence the mausoleum erected by Ponti in the center of the cemetery in Gallarate (1865-1869. «Degli stili nell’architettura», ii, 1897, and the «Atlas» of Luigi Archinti (Chirtani borrow from the works of the French diplomat detailed surveys of churches and mon- asteries of Syria indicated by Boito as models for future architects. The eastern route is continued in Milan and

  13. JC virus antibody index in natalizumab-treated patients: correlations with John Cunningham virus DNA and C-reactive protein level

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    Lanzillo R

    2014-10-01

    Full Text Available Roberta Lanzillo,1 Raffaele Liuzzi,2 Luca Vallefuoco,3 Marcello Moccia,1 Luca Amato,1 Giovanni Vacca,1 Veria Vacchiano,1 Giuseppe Portella,3 Vincenzo Brescia Morra1 1Neurological Sciences Department, Federico II University, 2Institute of Biostructure and Bioimaging, National Research Council, 3Clinical Pathology Department, Federico II University, Naples, ItalyAbstract: Natalizumab-treated patients have a higher risk of developing progressive multifocal leukoencephalopathy. Exposure to John Cunningham virus (JCV is a prerequisite for PML (progressive multifocal leukoencephalopathy. To assess JCV exposure in multiple sclerosis patients, we performed a serological examination, obtained the antibody index, performed real-time polymerase chain reaction (PCR to detect JCV DNA in plasma and urine, and investigated the role of ultrasensitive C-reactive protein (usCRP as a possible biological marker of JCV reactivation. We retrospectively analyzed consecutive natalizumab-treated multiple sclerosis patients who underwent a JCV antibody test through a two-step enzyme-linked immunosorbent assay (STRATIFY test to the measure of serum usCRP levels, and to perform blood and urine JCV PCR. The studied cohort included 97 relapsing–remitting patients (60 women. Fifty-two patients (53.6% tested positive for anti-JCV antibodies. PCR showed JCV DNA in the urine of 30 out of 83 (36.1% patients and 28 out of 44 seropositive patients (63.6%, with a 6.7% false-negative rate for the STRATIFY test. Normalized optical density values were higher in urinary JCV DNA-positive patients (P<0.0001. Interestingly, the level of usCRP was higher in urinary JCV DNA-positive patients and correlated to the number of DNA copies in urine (P=0.028. As expected, patients' age correlated with JCV seropositivity and with JC viruria (P=0.02 and P=0.001, respectively. JC viruria was significantly correlated with a high JCV antibody index and high serum usCRP levels. We suggest that PCR and

  14. Rasagiline for sleep disorders in patients with Parkinson’s disease: a prospective observational study

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    Schettino C

    2016-09-01

    Full Text Available Carla Schettino,1,2,* Clemente Dato,1,2,* Guglielmo Capaldo,1,2 Simone Sampaolo,1,2 Giuseppe Di Iorio,1,2 Mariarosa AB Melone1,2 1Department of Medical, Surgical, Neurological, Metabolic Sciences, and Aging, 2Division of Neurology and InterUniversity Center for Research in Neurosciences, Second University of Naples, Naples, Italy *These authors contributed equally to this work Introduction: Rasagiline is a selective, irreversible monoamine oxidase B inhibitor that ameliorates the symptoms of Parkinson’s disease (PD by inhibiting striatal dopamine metabolism. There is also evidence that monoamine oxidase B inhibitors increase melatonin levels in the pineal gland and may have a beneficial effect on sleep disorders, which are a common feature in patients with PD.Methods: This single-center, prospective, observational, 12-week study compared the effect of combination therapy with levodopa 200–300 mg/d + rasagiline 1 mg/d (n=19 with levodopa 200–300 mg/d alone (n=19 in the treatment of sleep disorders in patients with idiopathic PD.Results: After 12 weeks’ treatment, mean sleep latency was significantly (P<0.001 lower and the improvement in sleep latency from baseline was significantly (P=0.001 greater in patients receiving levodopa + rasagiline than in patients receiving levodopa alone. Similarly, at the end of the study, the mean total sleep time was significantly (P=0.002 longer and the improvement from baseline in mean total sleep time was significantly (P=0.026 greater in patients receiving levodopa + rasagiline than levodopa alone. There were no significant differences between treatment groups for the mean number of awakenings reported at week 12 nor the change from baseline to week 12 in mean number of awakenings.Conclusion: Adding rasagiline to levodopa improved sleep outcomes and may be an appropriate option for patients with PD experiencing sleep disorders. Keywords: Parkinson’s disease, rasagiline, sleep disorders, Parkinson

  15. Economic and organizational sustainability of a negative-pressure portable device for the prevention of surgical-site complications

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    Foglia E

    2017-06-01

    Full Text Available Emanuela Foglia,1 Lucrezia Ferrario,1 Elisabetta Garagiola,1 Giuseppe Signoriello,2 Gianluca Pellino,3 Davide Croce,1,4 Silvestro Canonico3 1Centre for Health Economics, Social and Health Care Management - LIUC University, Castellanza, Italy; 2Department of Mental Health and Preventive Medicine, University of Campania “Luigi Vanvitelli”, Naples, Italy; 3School of Medicine, University of Campania “Luigi Vanvitelli”, Naples, Italy; 4School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South \tAfrica Purpose: Surgical-site complications (SSCs affect patients’ clinical pathway, prolonging their hospitalization and incrementing their management costs. The present study aimed to assess the economic and organizational implications of a portable device for negative-pressure wound therapy (NPWT implementation, compared with the administration of pharmacological therapies alone for preventing surgical complications in patients undergoing general, cardiac, obstetrical–gynecological, or orthopedic surgical procedures.Patients and methods: A total of 8,566 hospital procedures, related to the year 2015 from one hospital, were evaluated considering infection risk index, occurrence rates of SSCs, drug therapies, and surgical, diagnostic, and specialist procedures and hematological exams. Activity-based costing and budget impact analyses were implemented for the economic assessment.Results: Patients developing an SSC absorbed i 64.27% more economic resources considering the length of stay (€ 8,269±2,096 versus € 5,034±2,901, p<0.05 and ii 42.43% more economic resources related to hematological and diagnostic procedures (€ 639±117 versus € 449±72, p<0.05. If the innovative device had been used over the 12-month time period, it would have decreased the risk of developing SSCs; the hospital would have realized an average reduction in health care expenditure equal to −0.69% (−€ 483

  16. Urinary protein profiles in ketorolac-associated acute kidney injury in patients undergoing orthopedic day surgery

    Directory of Open Access Journals (Sweden)

    Mariano F

    2017-09-01

    Full Text Available Filippo Mariano,1 Chiara Cogno,1 Fulvia Giaretta,2,3 Ilaria Deambrosis,2,3 Simona Pozza,4 Maurizio Berardino,5 Giuseppe Massazza,6 Luigi Biancone1,3 1Department of General and Specialist Medicine, Nephrology, Dialysis and Transplantation Unit, City of Health and Science, CTO Hospital, Turin, 2Department of General and Specialist Medicine, Laboratory of Nephrology and Immunopathology, City of Health and Science, Molinette Hospital, Turin, 3Department of Medical Sciences, University of Turin, Turin, 4Department of Radiology and Radiotherapy, CTO Radiology, City of Health and Science, CTO Hospital, Turin, 5Department of Anesthesiology and Intensive Care, Anesthesiology and Intensive Care 5, City of Health and Science, CTO Hospital, Turin, 6Department of Orthopedics and Traumatology, Week Hospital Unit, City of Health and Science, CTO Hospital, and University of Turin, Turin, Italy Background: Parenteral administration of ketorolac is very effective in controlling postoperative pain for orthopedic surgery. Ketorolac can induce clinically relevant renal alterations in elderly patients, whereas its short course is considered safe for young adults with normal preoperative renal function. In this study, of a cohort of young adults undergoing elective orthopedic day surgery, we sought cases complicated by readmission due to acute kidney injury (AKI.Patients and methods: Among 1397 young adults, aged 18–32 years who were admitted to undergo orthopedic day surgery from 2013 to 2015, four patients (0.29%, three males/one female treated in postprocedure with ketorolac (from 60 to 90 mg/day for 1–2 days were readmitted for suspected severe AKI. We evaluated functional outcome, urinary protein profiles and kidney biopsy (1 patient.Results: After day surgery discharge, they experienced gastrointestinal disturbances, flank pain and fever. Readmitted on post-surgery days 3–4, they presented with oliguric AKI (creatinine range 158.4–466.4 µmol/L and

  17. Evidence for preferences of Italian patients for physician attire

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    Sotgiu G

    2012-04-01

    Full Text Available Giovanni Sotgiu1, Paolo Nieddu2, Laura Mameli2, Enrico Sorrentino2, Pietro Pirina3, Alberto Porcu4, Stefano Madeddu1, Manuela Idini1, Maddalena Di Martino1, Giuseppe Delitala2, Ida Mura1, Maria Pina Dore21Epidemiology and Medical Statistics Unit, Department of Biomedical Sciences, 2Clinica Medica, 3Pneumologia, 4Chirurgia dell’Obesità, University of Sassari, Sassari, ItalyBackground: The relationship between patient and physician is a complex interaction that includes multiple factors. The objective of this study was to explore Italian patients’ preferences regarding physician appearance.Methods: A questionnaire was developed to survey patients in different medical and surgical settings; each subject was asked to choose one picture of either a male or female physician from a selection of different attires (professional, casual, surgical scrubs, trendy, and careless. Patients were also surveyed about issues such as the presence of a name tag, hair length, trousers on women, amount of makeup, presence of tattoos, and body piercing. Statistical analysis was performed using a Chi-square test.Results: A total of 765 questionnaires (534 completed from patients waiting for an internal medicine visit and 231 for other subspecialties were completed. The majority (45% of patients preferred the gastroenterologist to wear a surgical scrub with a white coat. For the other specialists, patients accepted either scrubs or formal dress under a white coat (P ≤ 0.05, with a name tag. Trendy attire was preferred by nine patients (1.1%. The entire sample judged it inappropriate for clinicians to have long hair, visible tattoos, body piercing, and, for women, to wear trousers and use excessive makeup.Conclusion: This is the first study conducted in Italy regarding physician attire. As in other Western countries, Italian patients favor physicians in professional attire with a white coat. Wearing professional dress is part of “etiquette based medicine” and

  18. Cognitive behavioral therapy to aid weight loss in obese patients: current perspectives

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    Castelnuovo G

    2017-06-01

    Full Text Available Gianluca Castelnuovo,1,2 Giada Pietrabissa,1,2 Gian Mauro Manzoni,1,3 Roberto Cattivelli,1,2 Alessandro Rossi,1 Margherita Novelli,1 Giorgia Varallo,1 Enrico Molinari1,2 1Psychology Research Laboratory, Istituto Auxologico Italiano IRCCS, San Giuseppe Hospital, Verbania, 2Department of Psychology, Catholic University of Milan, Milan, 3Faculty of Psychology, eCampus University, Novedrate, Italy Abstract: Obesity is a chronic condition associated with risk factors for many medical ­complications and comorbidities such as cardiovascular diseases, some types of cancer, osteoarthritis, hypertension, dyslipidemia, hypercholesterolemia, type-2 diabetes, obstructive sleep apnea syndrome, and different psychosocial issues and psychopathological disorders. Obesity is a highly complex, multifactorial disease: genetic, biological, psychological, behavioral, familial, social, cultural, and environmental factors can influence in different ways. Evidence-based strategies to improve weight loss, maintain a healthy weight, and reduce related comorbidities typically integrate different interventions: dietetic, nutritional, physical, behavioral, psychological, and if necessary, pharmacological and surgical ones. Such treatments are implemented in a multidisciplinary context with a clinical team composed of endocrinologists, nutritionists, dietitians, physiotherapists, psychiatrists, psychologists, and sometimes surgeons. Cognitive behavioral therapy (CBT is traditionally recognized as the best established treatment for binge eating disorder and the most preferred intervention for obesity, and could be considered as the first-line treatment among psychological approaches, especially in a long-term perspective; however, it does not necessarily produce a successful weight loss. Traditional CBT for weight loss and other protocols, such as enhanced CBT, enhanced focused CBT, behavioral weight loss treatment, therapeutic education, acceptance and commitment therapy

  19. Cardiovascular risk evaluation and prevalence of silent myocardial ischemia in subjects with asymptomatic carotid artery disease

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    Ciccone M

    2011-03-01

    Full Text Available Marco Matteo Ciccone1, Artor Niccoli-Asabella2, Pietro Scicchitano1, Michele Gesualdo1, Antonio Notaristefano2, Domenico Chieppa1, Santa Carbonara1, Gabriella Ricci1, Marco Sassara1, Corinna Altini2, Giovanni Quistelli1, Mario Erminio Lepera1, Stefano Favale1, Giuseppe Rubini21Cardiovascular Diseases Section, Department of Emergency and Organ Transplantation (DETO, 2Nuclear Medicine Unit, Department of Internal Medicine and of Public Medicine, University of Bari, Bari, ItalyIntroduction: Silent ischemia is an asymptomatic form of myocardial ischemia, not associated with angina or anginal equivalent symptoms, which can be demonstrated by changes in ECG, left ventricular function, myocardial perfusion, and metabolism. The aim of this study was to evaluate the prevalence of silent myocardial ischemia in a group of patients with asymptomatic carotid stenosis.Methods: A total of 37 patients with asymptomatic carotid plaques, without chest pain or dyspnea, was investigated. These patients were studied for age, sex, hypertension, diabetes, dyslipidemia, smoking, and family history of cardiac disease, and underwent technetium-99 m sestamibi myocardial stress-rest scintigraphy and echo-color Doppler examination of carotid arteries.Results: A statistically significant relationship (P = 0.023 was shown between positive responders and negative responders to scintigraphy test when both were tested for degree of stenosis. This relationship is surprising in view of the small number of patients in our sample. Individuals who had a positive scintigraphy test had a mean stenosis degree of 35% ± 7% compared with a mean of 44% ± 13% for those with a negative test. Specificity of our detection was 81%, with positive and negative predictive values of 60% and 63%, respectively.Conclusion: The present study confirms that carotid atherosclerosis is associated with coronary atherosclerosis and highlights the importance of screening for ischemic heart disease in

  20. 11th International Conference on Clustering Aspects of Nuclear Structure and Dynamics

    International Nuclear Information System (INIS)

    2017-01-01

    Preface The 11 th edition of the International Conference on Clustering Aspects of Nuclear Structure and Dynamics (CLUSTER‘16) was held in Napoli, Italy, on May 23-27 2016. All the Conference Sessions took place in the magnificent Complesso Monumentale dei Ss. Marcellino e Festo , located in the Historical Centre of Naples. This is one of the most prestigious building complexes of the Federico II University of Naples, the main home institution of the organizers, together with the Istituto Nazionale di Fisica Nucleare (Naples division). This building is 500 years old; in the XVIII century, it was reshaped by Luigi Vanvitelli, a famous architect of the pre-Neoclassical period in Italy, designer of the prestigious Royal Palace in the near town of Caserta. The site of Plenary Sessions was the Church of Ss. Marcellino e Festo , where all the participants were surrounded by the Baroque frescoes by Belisario Corenzio and, among the others, the paintings of Battistello Caracciolo, Massimo Stanzione, Giuseppe Simonelli and Francesco De Mura, important artists of the late Baroque period in South Italy. The sites of Parallel Sessions were two halls in the arcade of the S. Marcellino cloister: this gave the opportunity to the participants to enjoy the beauty of the architecture of the cloister with its fountains, gardens, sculptures. As organizers of the Conference, our main aims were: (1) to provide an excellent programme, with the expectation to be a reference point for the Nuclear Cluster Physics in the next four years; (2) to assure a very relaxing stay to the participants, allowing them to explore the bounty of artistic, and also culinary, masterpieces that Naples offers to its guests. The first point was assured by all the conveners that, with their excellent talks, gave a very precise and complete overview of the most recent achievements on Nuclear Cluster Physics, both from the experimental and theoretical point of view. We are indebted with the International

  1. Family accommodation in adult obsessive–compulsive disorder: clinical perspectives

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    Albert U

    2017-09-01

    Full Text Available Umberto Albert, Alessandra Baffa, Giuseppe Maina Rita Levi Montalcini Department of Neuroscience, A.O.U. San Luigi Gonzaga, University of Turin, Turino, Italy Abstract: The term accommodation has been used to refer to family responses specifically related to obsessive–compulsive (OC symptoms: it encompasses behaviors such as directly participating in compulsions, assisting a relative with obsessive–compulsive disorder (OCD when he/she is performing a ritual, or helping him/her to avoid triggers that may precipitate obsessions and compulsions. At the opposite side, family responses to OCD may also include interfering with the rituals or actively opposing them; stopping accommodating OC symptoms or actively interfering with their performance is usually associated with greater distress and sometimes even with aggressive behaviors from the patients. This article summarizes progress of the recent research concerning family accommodation in relatives of patients with OCD. Family accommodation is a prevalent phenomenon both among parents of children/adolescents with OCD and relatives/caregivers of adult patients. It can be measured with a specific instrument, the Family Accommodation Scale, of which there are several versions available for use in clinical practice. The vast majority of both parents of children/adolescents with OCD and family members of adult patients show at least some accommodation; providing reassurances to obsessive doubts, participating in rituals and assisting the patient in avoidance are the most frequent accommodating behaviors displayed by family members. Modification of routine and modification of activities specifically due to OC symptoms have been found to be equally prevalent. Specific characteristics of patients (such as contamination/washing symptoms and of relatives (the presence of anxiety or depressive symptoms or a family history positive for another anxiety disorder are associated with a higher degree of family

  2. Proceedings of the 19th ASPA Congress, Cremona, June 7-10, 2011

    Directory of Open Access Journals (Sweden)

    Guest Editor: Giacomo Pirlo

    2011-06-01

    technological applications. Indeed, I would like to congratulate and thank all those who have organized the meeting and have collaborated in reviewing the summaries for what they have done for ASPA and the Italian Animal Science. Finally, I acknowledge the institutional agencies, in particular the Ministry of Agricultural, Food and Forestry Policies (MIPAAF, the Regione Lombardia and the Comune di Cremona, and the main sponsors, namely De Laval, SIS NIR and Consorzio Agrario. Prof. Giuseppe Pulina, President of Animal Science and Production Association

  3. Effects of antioxidant supplementation on the aging process

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    Domenico Fusco

    2007-10-01

    Full Text Available Domenico Fusco1, Giuseppe Colloca1, Maria Rita Lo Monaco1, Matteo Cesari1,21Department of Gerontology, Geriatrics and Physiatry; Catholic University of Sacred Heart, Rome, Italy; 2Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville, FLAbstract: The free radical theory of aging hypothesizes that oxygen-derived free radicals are responsible for the age-related damage at the cellular and tissue levels. In a normal situation, a balanced-equilibrium exists among oxidants, antioxidants and biomolecules. Excess generation of free radicals may overwhelm natural cellular antioxidant defences leading to oxidation and further contributing to cellular functional impairment. The identification of free radical reactions as promoters of the aging process implies that interventions aimed at limiting or inhibiting them should be able to reduce the rate of formation of aging changes with a consequent reduction of the aging rate and disease pathogenesis. Even if antioxidant supplementation is receiving growing attention and is increasingly adopted in Western countries, supporting evidence is still scarce and equivocal. Major limitations in literature are still needed to be addressed to better evaluate the potential benefits from antioxidant supplementation: 1 an improved understanding of oxidation mechanisms possibly at the basis of the aging process, 2 the determination of reliable markers of oxidative damage and antioxidant status, 3 the identification of a therapeutic window in which an eventual antioxidant supplementation may be beneficial, 4 a deeper knowledge of the antioxidant molecules which in several conditions act as pro-oxidants. In the present paper, after a preliminary introduction to the free radical theory of aging and the rationale of antioxidant supplementation as an anti-aging intervention, we will present an overview of evidence relating antioxidant supplementations with

  4. The use of sugammadex for bariatric surgery: analysis of recovery time from neuromuscular blockade and possible economic impact

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    De Robertis E

    2016-06-01

    Full Text Available Edoardo De Robertis,1 Geremia Zito Marinosci,1 Giovanni Marco Romano,1 Ornella Piazza,2 Michele Iannuzzi,1 Fabrizio Cirillo,1 Stefania De Simone,3 Giuseppe Servillo,1 1Department of Neurosciences, Reproductive and Odontostomatologic Sciences, University Federico II, Naples, 2Department of Medicine and Surgery, University of Salerno, Salerno, 3Institute for Research on Innovation and Services for Development, National Research Council, Naples, Italy Background: Neuromuscular block (NMB monitoring and use of reversal agents accelerate the recovery time and improve the workflow in the operating room. We aimed to compare recovery times after sugammadex or neostigmine administration, and estimate the time spent in operating theater and the possible economic impact of a faster recovery, in morbidly obese patients undergoing bariatric surgery. Methods: We conducted a retrospective study that analyzed data from records of morbidly obese patients (body mass index >40 kg/m2 undergoing elective laparoscopic bariatric surgery in which sugammadex or neostigmine were used to reverse NMB. Patients were divided in two groups: group 1 (sugammadex group [SUG] received rocuronium and sugammadex for reversal and group 2 (neostigmine group [NEO] received either rocuronium or cisatracurium and neostigmine. Data are presented as mean (standard deviation. Results: Compared with NEO, SUG group showed shorter times to achieve train-of-four ratio of 0.9 (P<0.05 and an Aldrete score of 10 (P<0.05, a higher cost (€146.7 vs €3.6 [P<0.05], plus a remarkable less duration of operating theater occupancy (P<0.05. Sugammadex cost accounted for 2.58% of the total cost per surgery, while neostigmine cost accounted for 0.06%. Total time saved in SUG group was 19.4 hours, which could be used to perform 12 extra laparoscopic sleeve gastrectomies. Conclusion: Reversal from NMB was significantly faster with sugammadex than with neostigmine. Although sugammadex was substantially

  5. Changes in spinal range of motion after a flexibility training program in elderly women

    Directory of Open Access Journals (Sweden)

    Battaglia G

    2014-04-01

    Full Text Available Giuseppe Battaglia,1,2 Marianna Bellafiore,1,2 Giovanni Caramazza,2 Antonio Paoli,3 Antonino Bianco,1,2 Antonio Palma1,2 1Department of Law, Society, and Sport Sciences, University of Palermo, Palermo, Italy; 2Sicilian Regional Sports School of Italian National Olympic Committee (CONI, Sicily, Italy; 3Department of Biomedical Sciences, University of Padova, Padova, Italy Background: Aging-related reduced spinal mobility can interfere with the execution of important functional skills and activities in elderly women. Although several studies have shown positive outcomes in response to spinal flexibility training programs, little is known about the management of sets and repetitions in training protocols. The purpose of this study was to investigate the effects of an 8-week specific and standardized flexibility training program on the range of spinal motion in elderly women. Methods: Participants were recruited in a senior center of Palermo and randomly assigned in two groups: trained group (TG and control group (CG, which included 19 and 18 women, respectively. TG was trained for 8 weeks at two sessions/week. In particular, every session included three phases: warm up (~10 minutes, central period (~50 minutes, and cool down (~10 minutes. CG did not perform any physical activity during the experimental period. Spinal ranges of motion (ROM were measured from neutral standing position to maximum bending position and from neutral standing position to maximum extension position before and after the experimental period, using a SpinalMouse® device (Idiag, Volkerswill, Switzerland. Results: After the training period, TG showed an increase in spinal inclination by 16.4% (P<0.05, in sacral/hip ROM by 29.2% (P<0.05, and in thoracic ROM by 22.5% (P>0.05 compared with CG from maximum extension position to maximum bending position. We did not observe any significant difference in TG's lumbar ROM compared with CG after the training period (P>0.05. Conclusion

  6. El partisano Johnny (novela, fragmento

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    Beppe Fenoglio

    2013-07-01

    Full Text Available GIUSEPPE "BEPPE" FENOGLIO (Alba, 1922 – Turín, 1963. Hijo primogénito de una familia de tres hijos, Beppe nació en Alba en las Langhe el 1 de marzo 1922. En 1940 se inscribe en la facultad de Letras de la Universidad de Turín, en la que estuvo hasta 1943, momento en el que fue reclutado por el ejército y mandado primero a Ceva (Cuneo y después a Pietralata (Roma, donde realizó la instrucción militar. Tras el abandono que siguió al 8 de septiembre de 1943, Fenoglio se une primero en enero de 1944 a las formaciones partisanas. En un primer momento se enrola con los "rojos" de las Brigadas Garibaldi, pero pronto se une a los badogliani en el 1º Gruppo Divisioni Alpine comandado por Enrico Martini "Mauri" y en la 2ª Divisione Langhe comandada por Piero Balbo que operaba en las Langhe, entre Mango, Murazzano y Mombarcaro. En 1949 inicia con su primer cuento, Il trucco, una breve pero fundamental carrera literaria que se afirmará al año siguiente, cuando entre en contacto con el grupo de autores reunidos en torno a la editorial Einaudi, dando a la luz títulos de la altura de Racconti della guerra civile, La paga del sabato, I ventitré giorni della città di Alba o Primavera di belleza. A finales de 1959 se le diagnostica una grave enfermedad respiratoria que se complicará a lo largo de los tres años siguientes y que le causará la muerte en febrero de 1963. De la obra culmen de su carrera, la póstuma Il partigiano Johnny, ofrecemos las páginas iniciales con la estupenda traducción de Pepa Linares, recientemente publicada en castellano por Sajalín Editores. Normal 0 21 false false false ES X-NONE X-NONE  

  7. Scaling up health knowledge at European level requires sharing integrated data: an approach for collection of database specification

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    Menditto E

    2016-06-01

    Full Text Available Enrica Menditto,1 Angela Bolufer De Gea,2 Caitriona Cahir,3,4 Alessandra Marengoni,5 Salvatore Riegler,1 Giuseppe Fico,6 Elisio Costa,7 Alessandro Monaco,8 Sergio Pecorelli,5 Luca Pani,8 Alexandra Prados-Torres9 1School of Pharmacy, CIRFF/Center of Pharmacoeconomics, University of Naples Federico II, Naples, Italy; 2Directorate-General for Health and Food Safety, European Commission, Brussels, Belgium; 3Division of Population Health Sciences, Royal College of Surgeons in Ireland, 4Department of Pharmacology and Therapeutics, St James’s Hospital, Dublin, Ireland; 5Department of Clinical and Experimental Science, University of Brescia, Brescia; 6Life Supporting Technologies, Photonics Technology and Bioengineering Department, School of Telecomunications Engineering, Polytechnic University of Madrid, Madrid, Spain; 7Faculty of Pharmacy, University of Porto, Porto, Portugal; 8Italian Medicines Agency – AIFA, Rome, Italy; 9EpiChron Research Group on Chronic Diseases, Aragón Health Sciences Institute (IACS, IIS Aragón REDISSEC ISCIII, Miguel Servet University Hospital, University of Zaragoza, Zaragoza, Spain Abstract: Computerized health care databases have been widely described as an excellent opportunity for research. The availability of “big data” has brought about a wave of innovation in projects when conducting health services research. Most of the available secondary data sources are restricted to the geographical scope of a given country and present heterogeneous structure and content. Under the umbrella of the European Innovation Partnership on Active and Healthy Ageing, collaborative work conducted by the partners of the group on “adherence to prescription and medical plans” identified the use of observational and large-population databases to monitor medication-taking behavior in the elderly. This article describes the methodology used to gather the information from available databases among the Adherence Action Group partners

  8. PORTRAIT GRAFFITI IN MARGINS OF ANTIQUE LITHUANIAN BOOKS

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    Burba, Domininkas

    2006-12-01

    discharge. The marginal portraits in personal books are more artistical and their composition is more relaxed. Overall the GDL marginal portraits reveal quite a few similarities to the graffiti (in italian scarabocchi left in the documents by the workers of Naples bank archive. They were properly examined and classified by the artist and archivist Giuseppe Zevola. According to him this documental graffiti was born out of opposition to the grey everyday routine and experience of “pleasure of anxiety”.

  9. Efficacy and safety evaluation of pentoxifylline associated with other antioxidants in medical treatment of Peyronie's disease: a case-control study

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    Paulis G

    2015-12-01

    Full Text Available Gianni Paulis,1,2 Davide Barletta,3 Paolo Turchi,4 Antonio Vitarelli,5 Giuseppe Dachille,6 Andrea Fabiani,7 Romano Gennaro8 1Regina Apostolorum Hospital, Andrology Center, Albano L, 2Castelfidardo Medical Team, Peyronie's Disease Care Center, Rome, 3Department of Urology, Andrology Center, San Matteo Hospital, Pavia, 4Azienda ASL 4 Prato – Andrology Service, Prato, 5Department of Urology, University of Bari, 6Department of Urology, S Giacomo Hospital, Monopoli, Bari, 7Department of Surgery, Section of Urology and Andrology, Macerata, 8Department of Urologic Oncology, Section of Avellino, Italian League Against Cancer, Avellino, Italy Abstract: Peyronie's disease (PD is a chronic disorder involving the tunica albuginea surrounding the corpora cavernosa of the penis. A conservative treatment is indicated in the first stage of disease. The aim of this study was to assess the therapeutic impact and possible side effects of treatment with pentoxifylline (PTX in combination with other antioxidants in 307 patients with early-stage PD. Patients were subdivided into three groups: A, B, and C. Both groups, A and B, comprising of 206 patients, underwent treatment, whereas Group C was the control group (n=101. Treatment lasted 6 months and included the following: Group A: PTX 400 mg twice a day + propolis 600 mg/d + blueberry 160 mg/d + vitamin E 600 mg/d + diclofenac 4% gel twice/a day + PTX 100 mg via perilesional penile injection/every other week (12 injections in all; Group B: the same treatment as Group A except for the penile PTX injections. After the 6-month treatment course, we obtained the following results: actual mean decrease in plaque volume -46.9% and -24.8% in Group A and B, respectively (P<0.0001; mean curvature reduction -10.1° and -4.8°, respectively (P<0.0001; resolution of pain in 67.6% and 67.2% of cases, respectively (P=0.961; recovery of normal penile rigidity in 56.09% and 23.5% of cases, respectively (P=0.005. After 6 months

  10. In vivo visualization of photoreceptor layer and lipofuscin accumulation in Stargardt’s disease and fundus flavimaculatus by high resolution spectral-domain optical coherence tomography

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    Giuseppe Querques

    2009-12-01

    Full Text Available Giuseppe Querques, Rosy Prato, Gabriel Coscas, Gisèle Soubrane, Eric H SouiedDepartment of Ophthalmology, Hopital Intercommunal de Creteil, University Paris XII, FranceIntroduction: To assess photoreceptor (PR layer morphology in patients with Stargardt’s disease (STGD and fundus flavimaculatus (FFM using high resolution spectral domain optical coherence tomography (HD-OCT; OCT 4000 Cirrus, Humphrey-Zeiss, San Leandro, CA.Methods: This was a prospective observational case series. Sixteen consecutive patients with STGD and FFM underwent a complete ophthalmologic examination. Optical coherence tomography examination was performed with HD-OCT, a high-speed (27,000 axial scans per second OCT system using spectral/Fourier domain detection, with an axial image resolution of 5 µm.Results: A total of 31 eyes were included in the study. Transverse loss of the PR layer in the foveal region was shown by HD-OCT. Twenty eyes with clinically evident central atrophy had a disruption of either the Verhoeff‘s membrane (VM or the layer corresponding to the interface of inner segment (IS and outer segment (OS of PR in the foveal region. Among these eyes, 12/20 eyes had a loss of the PR layer (loss of both VM and IS-OS interface in the foveal region. Eleven eyes (11/31 without clinically evident central atrophy had an intact interface of IS and OS of PR centrally. Moreover, we observed hyperreflective deposits: type 1 lesions located within the retinal pigment epithelium (RPE layer and at the level of the outer segments of PR, and type 2 lesions located at the level of the outer nuclear layer and clearly separated from the RPE layer. Type 1 lesions alone were associated with absence of loss of the PR layer in the foveal region in all eyes; type 2 lesions were always associated with presence of type 1 lesions, and often (8/12 eyes associated with loss of the PR layer within the foveal region. Mean best-corrected visual acuity (BCVA was significantly

  11. Coronary artery disease in Africa and the Middle East

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    Kurdi MI

    2012-02-01

    Full Text Available Wael Almahmeed1, Mohamad Samir Arnaout2, Rafik Chettaoui3, Mohsen Ibrahim4, Mohamed Ibrahim Kurdi5, Mohamed Awad Taher6, Giuseppe Mancia71Heart and Vascular Institute, Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates; 2American University of Beirut Medical Center, Beirut, Lebanon; 3General and Cardiovascular Clinic of Tunis, Tunisia; 4Cairo University, Cairo, Egypt; 5King Khalid University Hospital and The Kingdom Hospital, Saudi Arabia; 6Ain Shams University School of Medicine, Cairo, Egypt; 7University of Milan, Bicocca, Milan, ItalyAbstract: Countries in Africa and the Middle East bear a heavy burden from cardiovascular disease. The prevalence of coronary heart disease is promoted in turn by a high prevalence of cardiovascular risk factors, particularly smoking, hypertension, dyslipidemia, diabetes, and sedentary lifestyles. Patients in Africa and the Middle East present with myocardial infarction at a younger age, on average, compared with patients elsewhere. The projected future burden of mortality from coronary heart disease in Africa and the Middle East is set to outstrip that observed in other geographical regions. Recent detailed nationally representative epidemiological data are lacking for many countries, and high proportions of transient expatriate workers in countries such as Saudi Arabia and the United Arab Emirates complicate the construction of such datasets. However, the development of national registries in some countries is beginning to reveal the nature of coronary heart disease. Improving lifestyles (reducing calorie intake and increasing physical activity in patients in the region will be essential, although cultural and environmental barriers will render this difficult. Appropriate prescribing of pharmacologic treatments is essential in the prevention and management of cardiovascular disease. In particular, recent controversies relating to the therapeutic profile of beta-blockers may have reduced their use. The

  12. Demographic variables, clinical aspects, and medicolegal implications in a population of patients with adjustment disorder

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    Anastasia A

    2016-04-01

    Full Text Available Annalisa Anastasia,1 Chiara Colletti,1 Valentina Cuoco,1 Adele Quartini,1 Stefania Urso,2 Raffaella Rinaldi,2 Giuseppe Bersani1 1Department of Medical-Surgical Sciences and Biotechnologies, Faculty of Pharmacy and Medicine, Sapienza University of Rome, 2Department of Anatomical, Istological, Forensic and Locomotor System Sciences, Sapienza University of Rome, Rome, Italy Introduction: Although adjustment disorder (AD is considered as residual diagnosis and receives little attention in research, it plays an important role in clinical practice and also assumes an increasingly important role in the field of legal medicine, where the majority of diagnostic frameworks (eg, mobbing often refer to AD. Our study aimed to look for specific stressor differences among demographic and clinical variables in a naturalistic setting of patients with AD.Methods: A restrospective statistical analysis of the data of patients diagnosed with AD from November 2009 to September 2012, identified via manual search from the archive of the outpatient setting at the University Unit of Psychiatry “A. Fiorini” Hospital, Terracina (Latina, Italy, was performed.Results: The sample consisted of 93 patients (46 males and 47 females, aged between 26 and 85, with medium–high educational level who were mainly employed. In most cases (54.80%, a diagnosis of AD with mixed anxiety and depressed mood was made. In all, 72% of the sample reported a negative family history for psychiatric disorders. In 22.60%, a previous history of psychopathology, especially mood disorders (76.19%, was reported. The main stressors linked to the development of AD were represented by working problems (32.30%, family problems (23.70%, and/or somatic disease (22.60% with significant differences with respect to age and sex. Half of the patients were subjected to a single first examination; 24.47% requested a copy of medical records.Conclusion: Confirming previous data from previous reports, our results

  13. Doppler ultrasound venous mapping of the lower limbs

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    Galeandro AI

    2012-02-01

    Full Text Available Aldo Innocente Galeandro1, Giovanni Quistelli2, Pietro Scicchitano2, Michele Gesualdo2, Annapaola Zito2, Paola Caputo2, Rosa Carbonara2, Giuseppe Galgano3, Francesco Ciciarello4, Sandro Mandolesi4, Claude Franceschi5, Marco Matteo Ciccone21Centro Diagnostica Globale and ASL-TA, Taranto, Italy; 2Cardiovascular Diseases Section, Department of Emergency and Organ Transplantation (DETO, University of Bari, Bari, Italy; 3Cardiovascular Diseases Section, Ente Ecclesiastico Ospedale Generale Regionale F Miulli, Acquaviva delle Fonti, Bari, Italy; 4Cardiology Department, Policlinico Umberto I, Sapienza University of Rome, Italy; 5Vascular Laboratories of Hospitals Saint Joseph and Pitié-Salpétrière, Paris, FranceBackground: The study aim was to test the accuracy (intra and interobserver variability, sensitivity, and specificity of a simplified noninvasive ultrasound methodology for mapping superficial and deep veins of the lower limbs.Methods: 62 consecutive patients, aged 62 ± 11 years, were enrolled. All underwent US-examinations, performed by two different investigators, of both legs, four anatomical parts, and 17 veins, to assess the interobserver variability of evaluation of superficial and deep veins of the lower limbs.Results: Overall the agreement between the second versus the first operator was very high in detecting reflux (sensitivity 97.9, specificity 99.7, accuracy 99.5; P = 0.80 at McNemar test. The higher CEAP classification stages were significantly associated with reflux (odds ratio: 1.778, 95% confidence interval: 1.552–2.038; P < 0.001 as well as with thrombosis (odds ratio: 2.765, 95% confidence interval: 1.741–4.389; P < 0.001. Thus, our findings show a strict association between the symptoms of venous disorders and ultrasound evaluation results for thrombosis or reflux.Conclusion: This study demonstrated that our venous mapping protocol is a reliable method showing a very low interobserver variability, which makes it

  14. Efficacy of intravitreal dexamethasone implant for prostaglandin-induced refractory pseudophakic cystoid macular edema: case report and review of the literature

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    Sacchi M

    2014-07-01

    Full Text Available Matteo Sacchi, Edoardo Villani, Francesca Gilardoni, Paolo Nucci University Eye Clinic, San Giuseppe Hospital, University of Milan, Milan, Italy Background: Macular edema is a known complication even after uneventful cataract surgery. The chronic use of prostaglandin analogs is a risk factor for the development of pseudophakic cystoid macular edema (CME. Nonsteroidal anti-inflammatory drugs (NSAIDs are considered first-line therapy but refractory postsurgical CME represents a therapeutic challenge, as there is not an evidence-based treatment.Objective: To report the use of a single implant of intravitreal dexamethasone for tafluprost-associated pseudophakic CME refractory to NSAIDs and to sub-Tenon’s corticosteroid injections.Case report: A 64-year-old female with ocular hypertension treated with tafluprost experienced decreased vision (visual acuity 20/60 and metamorphopsia 2 months after uneventful cataract extraction. Spectral domain optical coherence tomography (SD-OCT revealed CME. After 1 month of topical and oral NSAIDs, CME was still evident on SD-OCT (visual acuity 20/50. Two sub-Tenon’s betamethasone injections were performed at a 2-week interval. As CME was still present, 2 months after the diagnosis of CME (visual acuity 20/40, the patient underwent a single dexamethasone intravitreal implant. One month later, macular appearance was normal, and visual acuity increased to 20/30. This result was maintained throughout the 6 months of follow-up.Conclusion: In this report, a single implant of intravitreal dexamethasone successfully treated pseudophakic CME associated with the use of prostaglandin analogs unresponsive to NSAIDs and sub-Tenon’s betamethasone. The results of this report need to be corroborated by powered, prospective, randomized trials. The need for repeated treatments as well as the retreatment interval in patients requiring more than a single injection are issues still needing further investigations. Keywords

  15. Editorial

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    B. Rossaro

    2015-08-01

    Full Text Available The Journal of Entomological and Acarological Research (JEAR, formerly the Bollettino di Zoologia Agraria e di Bachicoltura of the Institute of Entomology of the University of Milan, was founded in 1928 by Remo Grandori (1928-1955. Prof. Grandori became the first Director of the journal, followed by his wife Luigia Grandori (1956-1957, Minos Martelli (1958-1985 and Luciano Süss (1986-2011. In 2012, the Editor, the Department of Agri-food Systems Protection (DiPSA - University of Milan, come to the decision to move from the paper version to the online open access version of JEAR, with the aim to reach all researchers in the field with a restyled editorial, and with Giuseppe Carlo Lozzia as Editor in Chief (2012-2014. Thanks to the contributions of prestigious scientists and young researchers from all over the world, the Journal published many papers, which were downloaded in numerous countries across the world. Recently, the new Editor, the Department of Food Environmental and Nutritional Sciences - University of Milan, named me as Editor-in-Chief and I happily accepted the invitation with the objective to give new energy to the JEAR through the publication of more and more research papers of recognized scientific quality. The Journal will maintain its actual structure with four subject areas steered by internationally recognized Section Editors, who are now supported by a new and larger Editorial Board. The JEAR publishes papers on systematics, geographical speciation and evolution, aquatic and terrestrial entomology, ecological system dynamics, phenology and modelling for integrated pest control, agricultural and stored product pests, urban veterinary and forensic entomology, plant insect interaction and ecosystems, biological control and agro-ecology, and all other subjects related to the four subject areas. I hope the journal will continue to receive the attention of the researchers, in particular our younger colleagues in whose hands is

  16. Accurate Influenza Monitoring and Forecasting Using Novel Internet Data Streams: A Case Study in the Boston Metropolis.

    Science.gov (United States)

    Lu, Fred Sun; Hou, Suqin; Baltrusaitis, Kristin; Shah, Manan; Leskovec, Jure; Sosic, Rok; Hawkins, Jared; Brownstein, John; Conidi, Giuseppe; Gunn, Julia; Gray, Josh; Zink, Anna; Santillana, Mauricio

    2018-01-09

    on multiple data sources, including ARGO, produced the most robust and accurate results. The observed Pearson correlations between our out-of-sample flu activity estimates and those historically reported by the BPHC were 0.98 in nowcasting influenza and 0.94 in forecasting influenza 1 week ahead of the current date. We show that information from Internet-based data sources, when combined using an informed, robust methodology, can be effectively used as early indicators of influenza activity at fine geographic resolutions. ©Fred Sun Lu, Suqin Hou, Kristin Baltrusaitis, Manan Shah, Jure Leskovec, Rok Sosic, Jared Hawkins, John Brownstein, Giuseppe Conidi, Julia Gunn, Josh Gray, Anna Zink, Mauricio Santillana. Originally published in JMIR Public Health and Surveillance (http://publichealth.jmir.org), 09.01.2018.

  17. Preoperative risk factors in total thyroidectomy of substernal goiter

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    Bove A

    2016-11-01

    Full Text Available Aldo Bove, Raffaella Maria Di Renzo, Gauro D’Urbano, Manuela Bellobono, Vincenzo D’ Addetta, Alfonso Lapergola, Giuseppe Bongarzoni Department of Medicine, Dentistry and Biotechnology, University “G. d’Annunzio” Chieti-Pescara, Chieti Scalo, Italy Abstract: The definition of substernal goiter (SG is based on variable criteria leading to a considerable variation in the reported incidence (from 0.2% to 45%. The peri- and postoperative complications are higher in total thyroidectomy (TT for SG than that for cervical goiter. The aim of this study was to evaluate the preoperative risk factors associated with postoperative complications. From 2002 to 2014, 142 (8.5%; 98 women and 44 men of the 1690 patients who underwent TT had a SG. We retrospectively evaluated the following parameters: sex, age, histology, pre- and retrovascular position, recurrence, and extension beyond the carina. These parameters were then related to the postoperative complications: seroma/hematoma, transient and permanent hypocalcemia, transient and permanent laryngeal nerve palsy, and the length of surgery. The results were further compared with a control group of 120 patients operated on in the same period with TT for cervical goiter. All but two procedures were terminated via cervicotomy, where partial sternotomies were required. No perioperative mortality was observed. Results of the statistical analysis (Student’s t-test and Fisher’s exact test indicated an association between recurrence and extension beyond the carina with all postoperative complications. The group that underwent TT of SG showed a statistically significant higher risk for transient hypocalcemia (relative risk =1.767 with 95% confidence interval: 1.131–2.7605, P=0.0124, and need to treat =7.1 and a trend toward significance for transient recurrent laryngeal nerve palsy (relative risk =6.7806 with 95% confidence interval: 0.8577–53.2898, P=0.0696, and need to treat =20.8 compared to the

  18. Evaluation of the stability of linezolid in aqueous solution and commonly used intravenous fluids

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    Taylor R

    2017-07-01

    Full Text Available Rachel Taylor, Bruce Sunderland, Giuseppe Luna, Petra Czarniak School of Pharmacy, Faculty of Health Sciences, Curtin University, Bentley, WA, Australia Purpose: The aim was to evaluate the stability of linezolid in commonly used intravenous fluids and in aqueous solution to determine the kinetics of degradation and shelf-life values at alkaline pH values. Methods: Forced degradation studies were performed on linezolid in solution to develop a validated high-performance liquid chromatography analysis. Sodium chloride 0.9%, sodium lactate, and glucose 5% and glucose 10% solution containing 2.0 mg/mL linezolid were stored at 25.0°C (±0.1°C for 34 days. The effect of temperature on the stability of linezolid in 0.1 M sodium hydroxide solution was investigated to determine the activation energy. The degradation rates of linezolid at selected pH values at 70.0°C and the influence of ionic strength were also examined. Activation energy data were applied to determine the shelf-life values at selected pH values, and a pH rate profile was constructed over the pH range of 8.7–11.4. The stability of intravenous linezolid (Zyvox® solution was evaluated by storing at 70.0°C for 72 hours. Results: Linezolid was found to maintain >95.0% of its initial concentration after storage at 25.0°C for 34 days in sodium lactate, 0.9% in sodium chloride, and 5% and 10% in glucose solutions. Linezolid was degraded at alkaline pH values by first-order kinetics. Activation energy data showed that temperature, but not ionic strength, influenced the degradation rate significantly. An activation energy of 58.22 kJ/mol was determined for linezolid in 0.1 M sodium hydroxide solution. Linezolid was least stable at high pH values and at elevated temperatures. It was determined that linezolid has adequate stability for the preparation of intravenous fluids for clinical administration. Conclusion: Linezolid was found to have a shelf life of 34 days at 25°C when added to

  19. Biocompatibility, endocytosis, and intracellular trafficking of mesoporous silica and polystyrene nanoparticles in ovarian cancer cells: effects of size and surface charge groups

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    Ekkapongpisit M

    2012-07-01

    Full Text Available Maneerat Ekkapongpisit,1 Antonino Giovia,1 Carlo Follo,1 Giuseppe Caputo,2,3 Ciro Isidoro11Laboratory of Molecular Pathology and Nanobioimaging, Department of Health Sciences, Università del Piemonte Orientale “A Avogadro”, Novara, 2Dipartimento di Chimica dell’Università di Torino, Torino, 3Cyanine Technology SpA, Torino, ItalyBackground and methods: Nanoparticles engineered to carry both a chemotherapeutic drug and a sensitive imaging probe are valid tools for early detection of cancer cells and to monitor the cytotoxic effects of anticancer treatment simultaneously. Here we report on the effect of size (10–30 nm versus 50 nm, type of material (mesoporous silica versus polystyrene, and surface charge functionalization (none, amine groups, or carboxyl groups on biocompatibility, uptake, compartmentalization, and intracellular retention of fluorescently labeled nanoparticles in cultured human ovarian cancer cells. We also investigated the involvement of caveolae in the mechanism of uptake of nanoparticles.Results: We found that mesoporous silica nanoparticles entered via caveolae-mediated endocytosis and reached the lysosomes; however, while the 50 nm nanoparticles permanently resided within these organelles, the 10 nm nanoparticles soon relocated in the cytoplasm. Naked 10 nm mesoporous silica nanoparticles showed the highest and 50 nm carboxyl-modified mesoporous silica nanoparticles the lowest uptake rates, respectively. Polystyrene nanoparticle uptake also occurred via a caveolae-independent pathway, and was negatively affected by serum. The 30 nm carboxyl-modified polystyrene nanoparticles did not localize in lysosomes and were not toxic, while the 50 nm amine-modified polystyrene nanoparticles accumulated within lysosomes and eventually caused cell death. Ovarian cancer cells expressing caveolin-1 were more likely to endocytose these nanoparticles.Conclusion: These data highlight the importance of considering both the

  20. Gender difference in response predictors after 1-year exenatide therapy twice daily in type 2 diabetic patients: a real world experience

    Directory of Open Access Journals (Sweden)

    Anichini R

    2013-04-01

    Full Text Available Roberto Anichini,1 Sabrina Cosimi,2 Alberto Di Carlo,3 Paola Orsini,4 Alessandra De Bellis,1 Giuseppe Seghieri,1 Flavia Franconi,5 Fabio Baccetti6 1Diabetes Unit, Spedali Riuniti, Pistoia, Italy; 2Diabetes Unit, Hospital of Versilia, Camaiore (LU, Italy; 3Diabetes Unit, Hospital of Lucca, Italy; 4Diabetes Unit, Hospital of Livorno, Italy; 5Department of Biochemical Sciences, University of Sassari, Italy; 6Diabetes Unit, Hospital of Massa, Italy Purpose: To investigate whether gender affects therapeutic response by exenatide twice a day (BID in type 2 diabetes by using a database concerning patients monitored by five outpatient clinics in Tuscany, Italy. Patients and methods: We considered a cohort of 315 (154 male/161 female patients experiencing therapeutic failure while on oral therapy (metformin, or combination therapy metformin + sulphonylureas, who were given exenatide (10 µg/BID and who fully completed 4 months, 8 months, and 12 months of follow-ups. Results: Among patients stratified by gender and well matched for age, body mass index, and hemoglobin A1c (HbA1c, it was found that the length of disease was longer in females than in males (12 ± 8 years versus 10 ± 7 years; P = 0.037, and the ratio of patients on metformin to those on combination therapy was higher in men (P = 0.018. Target glycemic response (1-year HbA1c ≤ 7% was achieved in a significantly higher proportion of males than females (38% versus 27%;Χ2 = 4.66; P = 0.03. Target weight loss expressed as 1-year weight percent fall from baseline ≥ 75th percentile (8.5% was significantly higher in females at 8 and 12 months (P < 0.05; for both. One-year glycemic target response was inversely related to baseline HbA1c levels and diabetes duration among males, while metformin therapy (compared to oral combination therapy was a significant predictor of better glycemic targets among females. Homeostasis model assessment-B, measured in 117 patients, predicted hypoglycemic

  1. The ESI scale, an ethical approach to the evaluation of seismic hazards

    Science.gov (United States)

    Porfido, Sabina; Nappi, Rosa; De Lucia, Maddalena; Gaudiosi, Germana; Alessio, Giuliana; Guerrieri, Luca

    2015-04-01

    The dissemination of correct information about seismic hazard is an ethical duty of scientific community worldwide. A proper assessment of a earthquake severity and impact should not ignore the evaluation of its intensity, taking into account both the effects on humans, man-made structures, as well as on the natural evironment. We illustrate the new macroseismic scale that measures the intensity taking into account the effects of earthquakes on the environment: the ESI 2007 (Environmental Seismic Intensity) scale (Michetti et al., 2007), ratified by the INQUA (International Union for Quaternary Research) during the XVII Congress in Cairns (Australia). The ESI scale integrates and completes the traditional macroseismic scales, of which it represents the evolution, allowing to assess the intensity parameter also where buildings are absent or damage-based diagnostic elements saturate. Each degree reflects the corresponding strength of an earthquake and the role of ground effects, evaluating the Intensity on the basis of the characteristics and size of primary (e.g. surface faulting and tectonic uplift/subsidence) and secondary effects (e.g. ground cracks, slope movements, liquefaction phenomena, hydrological changes, anomalous waves, tsunamis, trees shaking, dust clouds and jumping stones). This approach can be considered "ethical" because helps to define the real scenario of an earthquake, regardless of the country's socio-economic conditions and level of development. Here lies the value and the relevance of macroseismic scales even today, one hundred years after the death of Giuseppe Mercalli, who conceived the homonymous scale for the evaluation of earthquake intensity. For an appropriate mitigation strategy in seismic areas, it is fundamental to consider the role played by seismically induced effects on ground, such as active faults (size in length and displacement) and secondary effects (the total area affecting). With these perspectives two different cases

  2. Pressure injuries in elderly with acute myocardial infarction

    Directory of Open Access Journals (Sweden)

    Komici K

    2017-09-01

    Full Text Available Klara Komici,1 Dino F Vitale,2 Dario Leosco,1 Angela Mancini,1 Graziamaria Corbi,3 Leonardo Bencivenga,1 Alessandro Mezzani,4 Bruno Trimarco,5 Carmine Morisco,5 Nicola Ferrara,1,2 Giuseppe Rengo1,2 1Division of Geriatrics, Department of Translational Medical Sciences, University of Naples Federico II, Naples, Italy; 2Cardiac Rehabilitation Division, Salvatore Maugeri Foundation, IRCCS, Scientific Institute of Telese Terme (BN, Telese Terme, Italy; 3Department of Medicine and Health Sciences, University of Molise Campobasso, Campobasso, Italy; 4Cardiac Rehabilitation Division, Salvatore Maugeri Foundation, IRCCS, Scientific Institute of Veruno, Veruno, Italy; 5Division of Cardiology, Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy Objectives: To assess pressure injury (PI incidence among patients hospitalized for acute myocardial infarction (AMI in an intensive coronary care unit (ICCU and to detect the impact of specific risk factors on the development of PI in this clinical setting.Patients and methods: Prospective cohort study in ICCU setting. Patients admitted for AMI: patients mean age 67.5±11.5 years (n=165. Norton Scale, Mini Nutritional Assessment (MNA, demographic, clinical and biochemical data collected at the time of ICCU admission have been tested in a logistic model to assess the odds ratios (ORs of PI risk development. The jackknifed area under the receiver operating characteristic curve (AUC and the decision curve analysis have been employed to assess the additive predictive value of a factor.Results: Twenty-seven (16.3% patients developed PIs. An increased PI risk was associated with advanced age (OR =2.5 every 10-year increase; 95% CI =1.1–5.7, while probability of PI development was reduced in patients with higher left ventricular ejection fraction (LVEF (OR =0.4 every 5% increase; 95% CI =0.24–0.66, MNA score (OR =0.65 every unit change; 95% CI =0.44–0.95 and Norton Scale score

  3. The Journal “Geopolitica” and Formation of the Italian Geopolitical School

    Directory of Open Access Journals (Sweden)

    Maximilian Al’bertovich Shepelev

    2017-12-01

    Full Text Available The article reveals the origins, methodological features and the process of institutionalization of Italian geopolitical school, place and role of the journal “Geopolitica” in this process. The article analyzes the characteristics of Italian geopolitical perception of the world and its geostrategic priorities, formulated by the representatives of the Italian geopolitical schools in the period of its formation in 20-40-ies of the XX century (the Mediterranean - Mare nostrum, Euroafrica. The source of the formation of the Italian geopolitical school was the intellectual influence of irredentism un the age of the Risorgimento. The process of its formation was correlated with the formation of the modern national school of geographical science, in which was dominated the perception of geography as “utilitarian science” and developed the direction of “dynamic political geography”. Its specifical features was the “antideterminism” and “geographic humanism”, the recognition that the environment does not have absolute power over society, but political will is a determining factor in anthropogeographical area. The institutionalization of Italian political school promoted the creation of several research centres in the 20-30-ies and publishing from January 1939 to December 1942 magazine “Geopolitica”. The draft edition of this magazine received support from the minister of national education Giuseppe Bottai, it was headed by Professor Giorgio Roletto and his disciple, Ernesto Massi. Italian geopolitics maintained close ties with their German colleagues, but they were theoretically justified differences between “Latin” and “German” geopolitical worldviews. Unlike the German geopolitics, the concept of “living space” was used primarily in the economic sense, but it was not used in a racial-demographic sense. Italian geopolitics acted against the world order enshrined in the Treaty of Versailles, because it was protected

  4. Some contributions from the doctor of the miners in the Simplon tunnel: The most human of victories. The Provinces of Italy to the Simplon tunnel. The family of the miner at Simplon. 1906.

    Science.gov (United States)

    Volante, G

    2006-01-01

    Similarly to Daniele Pometta (1869-1949) on the northern front, Giuseppe Volante (1870-1936) from Turin, a valid clinician and hygiene expert was the field doctor for the firm of Brandt, Brandau e C., on the southern part of the Simplon tunnel for the whole period of its excavation (1898-1906). He meticulously organised and carried out with determination the main mission entrusted him which was to prevent the hookworm epidemic which a mere twenty years earlier had cast its shadow over the St. Gotthard tunnel. Volante also authoritatively directed the first aid post and the hospital that the company built at Nante. Evidence of Volante's vast medical experience was seen in the scientific works he published as well as in a report published in the acts of the International Conference on Work-related Illnesses (Volante, 1906a) and then in a comunication at No. 3 Italian Congress on Work-related Illnesses in Turin (Volante, 1911). There are three interesting works reproduced here (Volante, 1906b-c-d) which are substantially aimed at a broad readership and which clearly illustrate the work carried out, the experience gained and also the author's cultural background. Volante's remarks and the data he supplies are "official" but show no sign of partiality; they convey the grandness of the work he contributed towards creating and in some ways also the "generosity" of the company towards the labour force who "only" went on strike three times for better pay, fewer hours and improved working conditions. Volante's opinion on the low morbidity and mortality of the workers is certainly motivated although it is still relative, first and foremost because he had the tragedy of the St Gotthard as a yardstick, but also because it was swayed by the idea, widespread at the time, of fatalism about the potentially negative effects of the type of work. During the International Conference in 1906 Violante was awarded a gold medal for the work he had conducted, and for three years afterwards

  5. La traduction anglaise de Maria Stuarda : paradoxes et contradictions d’une reine catholique et puritaine The English Translation of Maria Stuarda: Paradoxes and Contradictions of a Catholic and Puritan Queen

    Directory of Open Access Journals (Sweden)

    Pierre Degott

    2011-12-01

    Full Text Available Cette étude vise à étudier l’unique traduction anglaise de l’opéra de Donizetti Maria Stuarda (1835, réalisée pour l’English National Opera en 1973. Dans le cadre d’une réflexion sur la « réécriture du patrimoine anglophone », ce travail cherche à montrer comment le recours à la traduction dans un contexte culturel particulier, la Grande-Bretagne des années 1970 et 1980, modifie considérablement les enjeux historiques et politiques qui ressortent de l’œuvre- source. Ainsi, si l’opéra de Donizetti propose une lecture « revisitée » de l’histoire, par le biais notamment l’œuvre de Schiller, le processus de la « traduction » permet lui aussi de recadrer et de recontextualiser le propos. On s’attachera ainsi à examiner le traitement des aspects historiques et religieux de l’opéra de Donizetti. Enfin, on pourra également analyser les modifications faites sur le plan musical, ainsi que sur celui de la distribution vocale. Loin d’être innocent, le choix assez curieux de Janet Baker – valeur « nationale » s’il en est – pour incarner l’infortunée reine Stuart n’était-il pas à lui-même destiné à émousser, ou à recadrer, les enjeux essentiels de l’ouvrage de Donizetti ?This article is about the only English singing-translation of Donizetti’s Maria Stuarda, as performed by the ENO in the 1970s and 80s. It aims at showing how the translated text considerably modifies the historical and political issues of the original version, the English text being a form of correction of the work of Schiller and Donizetti’s librettist, Giuseppe Bardari. If Donizetti’s work already offers, via Schiller, a somewhat revised version of History, the translation and recontextualisation of the opera pushes the transformation a little bit further. The paper thus examines some of the religious and historical aspects of such a cultural transfer, but also some of the musical modifications brought to

  6. Barium titanate nanoparticles and hypergravity stimulation improve differentiation of mesenchymal stem cells into osteoblasts

    Directory of Open Access Journals (Sweden)

    Rocca A

    2015-01-01

    Full Text Available Antonella Rocca,1,2 Attilio Marino,1,2 Veronica Rocca,3 Stefania Moscato,4 Giuseppe de Vito,5,6 Vincenzo Piazza,5 Barbara Mazzolai,1 Virgilio Mattoli,1 Thu Jennifer Ngo-Anh,7 Gianni Ciofani1 1Istituto Italiano di Tecnologia, Center for Micro-BioRobotics @SSSA, Pontedera, Italy, 2Scuola Superiore Sant’Anna, The BioRobotics Institute, Pontedera, Italy, 3Università di Pisa, Dipartimento di Ingegneria dell’Informazione, Pisa, Italy, 4Università di Pisa, Dipartimento di Medicina Clinica e Sperimentale, Pisa, Italy, 5Istituto Italiano di Tecnologia, Center for Nanotechnology Innovation @NEST, Pisa, Italy, 6Scuola Normale Superiore, NEST, Pisa, Italy, 7Directorate of Human Spaceflight and Operations, European Space Agency, Noordwijk, the Netherlands Background: Enhancement of the osteogenic potential of mesenchymal stem cells (MSCs is highly desirable in the field of bone regeneration. This paper proposes a new approach for the improvement of osteogenesis combining hypergravity with osteoinductive nanoparticles (NPs.Materials and methods: In this study, we aimed to investigate the combined effects of hypergravity and barium titanate NPs (BTNPs on the osteogenic differentiation of rat MSCs, and the hypergravity effects on NP internalization. To obtain the hypergravity condition, we used a large-diameter centrifuge in the presence of a BTNP-doped culture medium. We analyzed cell morphology and NP internalization with immunofluorescent staining and coherent anti-Stokes Raman scattering, respectively. Moreover, cell differentiation was evaluated both at the gene level with quantitative real-time reverse-transcription polymerase chain reaction and at the protein level with Western blotting.Results: Following a 20 g treatment, we found alterations in cytoskeleton conformation, cellular shape and morphology, as well as a significant increment of expression of osteoblastic markers both at the gene and protein levels, jointly pointing to a substantial

  7. Evaluation of effectiveness and safety of a herbal compound in primary insomnia symptoms and sleep disturbances not related to medical or psychiatric causes

    Directory of Open Access Journals (Sweden)

    Palmieri G

    2017-05-01

    Full Text Available Giancarlo Palmieri,1,2 Paola Contaldi,1 Giuseppe Fogliame1 1ANARDI Medical and Scientific Association, Scafati, Italy; 2Department of Internal Medicine, Niguarda Cà Granda Hospital, Milan, Italy Background and purpose: Sleep disturbances and related daytime activities impairment are common diseases nowadays. General practitioners are often the first health care professional asked to alleviate sleep disturbances and primary insomnia symptoms. Beyond a wide class of hypnotic drugs, botanicals can represent an alternative treatment for those kinds of symptoms. The scope of the present study is to evaluate safety and effectiveness of a herbal compound composed of valerian, hop, and jujube (Vagonotte® on primary insomnia symptoms and sleep disturbances not related to medical or psychiatric causes.Patients and methods: One hundred and twenty subjects with sleep disturbances symptoms were randomized in two branches of 60 persons each, receiving the herbal compound or placebo at dosage of two pills per day 30 minutes before their scheduled bedtime. All subjects were screened for precise items related to sleep quality and daytime activity at the beginning, after 10 days, and after 20 days of consecutive dietary supplement (or placebo consumption. The participants remained blind to group assignment until all of them completed the trial.Results: Sleep onset, numbers of nocturnal awakenings, and overall nocturnal slept time were assessed. A statistically significant difference between the two groups emerged. The group receiving the herbal compound showed a lower time of sleep onset compared to placebo group, the same result was obtained for total slept time and night awakenings frequency (p<0.001. Daily symptom improvement in subjects receiving the herbal compound showed significant reduction in tension and irritability, difficulty in concentration, and fatigue intensity, if compared to placebo scores (p<0.001. None of the 60 subjects in the verum group

  8. Long-term survival in elderly patients with a do-not-intubate order treated with noninvasive mechanical ventilation

    Directory of Open Access Journals (Sweden)

    Riario-Sforza GG

    2011-04-01

    Full Text Available Paolo Scarpazza1, Cristoforo Incorvaia2, Paolo Amboni3, Giuseppe di Franco1, Stefania Raschi1, Pierfranco Usai1, Monica Bernareggi1, Cristiano Bonacina1, Chiara Melacini1, Roberta Cattaneo1, Serena Bencini1, Chiara Pravettoni2, Gian Galeazzo Riario-Sforza2, Gianni Passalacqua4, Walter Casali11Divisione di Broncopneumotisiologia, Ospedale Civile, Vimercate, Italy; 2Pulmonary Rehabilitation, Istituti Clinici di Perfezionamento, Milan, Italy; 3Clinical Chemistry Laboratory, Ospedali Riuniti, Bergamo, Italy; 4Allergy and Respiratory Diseases, University Of Genoa, Genoa, ItalyBackground: Noninvasive mechanical ventilation (NIMV is an effective tool in treating patients with acute respiratory failure (ARF, since it reduces both the need for endotracheal intubation and the mortality in comparison with nonventilated patients. A particular issue is represented by the outcome of NIMV in patients referred to the emergency department for ARF and with a do-not-intubate (DNI status because of advanced age or excessively critical conditions. This study evaluated long-term survival in a group of elderly patients with acute hypercapnic ARF who had a DNI order and who were successfully treated by NIMV.Methods: The population consisted of 54 patients with a favorable outcome after NIMV for ARF. They were followed up for 3 years by regular control visits, with at least one visit every 4 months, or as needed according to the patient’s condition. Of these, 31 continued NIMV at home and 23 were on long-term oxygen therapy (LTOT alone.Results: A total of 16 of the 52 patients had not survived at the 1-year follow-up, and another eight patients died during the 3-year observation, with an overall mortality rate of 30.8% after 1 year and 46.2% after 3 years. Comparing patients who continued NIMV at home with those who were on LTOT alone, 9 of the 29 patients on home NIMV died (6 after 1 year and 3 after 3 years and 15 of the 23 patients on LTOT alone died (10 after 1

  9. Effects of low-carbohydrate diet therapy in overweight subject with autoimmune thyroiditis: possible synergism with ChREBP

    Directory of Open Access Journals (Sweden)

    Esposito T

    2016-09-01

    Full Text Available Teresa Esposito,1,2 Jean Marc Lobaccaro,3 Maria Grazia Esposito,4 Vincenzo Monda,1 Antonietta Messina,1 Giuseppe Paolisso,5 Bruno Varriale,2 Marcellino Monda,1 Giovanni Messina1,6 1Department of Experimental Medicine, Section of Human Physiology and Unit of Dietetics and Sports Medicine, 2Laboratory of Molecular Biology and Genetics, Department of Experimental Medicine, Second University of Naples, Naples, Italy; 3UMR, Clermont Université, Centre de Recherche en Nutrition Humaine d’Auvergne, Aubière Cedex, France; 4Complex Surgery Unit, Evangelic Hospital Villa Betania, 5Department of Scienze Mediche, Chirurgiche, Neurologiche, Metaboliche e dell’Invecchiamento, Second University of Naples, Naples, 6Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy Abstract: The thyroid is one of the metabolism regulating glands. Its function is to determine the amount of calories that the body has to burn to maintain normal weight. Thyroiditides are inflammatory processes that mainly result in autoimmune diseases. We have conducted the present study in order to have a clear picture of both autoimmune status and the control of body weight. We have evaluated the amount of either thyroid hormones, or antithyroid, or anti-microsomal, or anti-peroxidase antibodies (Abs in patients with high amounts of Abs. In a diet devoid of carbohydrates (bread, pasta, fruit, and rice, free from goitrogenic food, and based on body mass index, the distribution of body mass and intracellular and extracellular water conducted for 3 weeks gives the following results: patients treated as above showed a significant reduction of antithyroid (-40%, P<0.013, anti-microsomal (-57%, P<0.003, and anti-peroxidase (-44%, P<0,029 Abs. Untreated patients had a significant increase in antithyroid (+9%, P<0.017 and anti-microsomal (+30%, P<0.028 Abs. Even the level of anti-peroxidase Abs increased without reaching statistical significance (+16%, P>0064

  10. Drug discovery strategies in the field of tumor energy metabolism: Limitations by metabolic flexibility and metabolic resistance to chemotherapy.

    Science.gov (United States)

    Amoedo, N D; Obre, E; Rossignol, R

    2017-08-01

    metabolism and to follow the efficiency of a treatment at a preclinical or clinical stage. Relevant descriptors of tumor metabolism are now required to better stratify patients for the development of personalized metabolic medicine. In this review, we discuss the current limitations in basic research and drug discovery in the field of cancer metabolism to foster the need for more clinically relevant target identification and validation. We discuss the design of adapted drug screening assays and compound efficacy evaluation methods for the discovery of innovative anti-cancer therapeutic approaches at the level of tumor energetics. This article is part of a Special Issue entitled Mitochondria in Cancer, edited by Giuseppe Gasparre, Rodrigue Rossignol and Pierre Sonveaux. Copyright © 2017 Elsevier B.V. All rights reserved.

  11. Depressive symptoms in Parkinson’s disease and in non-neurological medical illnesses

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    Assogna F

    2013-03-01

    Full Text Available Francesca Assogna,1 Sabrina Fagioli,1 Luca Cravello,1 Giuseppe Meco,2 Mariangela Pierantozzi,3 Alessandro Stefani,3 Francesca Imperiale,2 Carlo Caltagirone,1,3 Francesco E Pontieri,4 Gianfranco Spalletta11I.R.C.C.S. Santa Lucia Foundation, Rome, Italy; 2Department of Neurology and Psychiatry (Parkinson’s Centre and Research Centre of Social Diseases (CIMS, University “Sapienza”, Rome, Italy; 3Department of Neuroscience, University “Tor Vergata”, Rome, Italy; 4Department of Neuroscience, Mental Health and Sensory Systems, University “Sapienza”, Movement Disorder Unit, Sant’Andrea Hospital, Rome, ItalyBackground: Patients with neurological and non-neurological medical illnesses very often complain of depressive symptoms that are associated with cognitive and functional impairments. We compared the profile of depressive symptoms in Parkinson’s disease (PD patients with that of control subjects (CS suffering from non-neurological medical illnesses.Methods: One-hundred PD patients and 100 CS were submitted to a structured clinical interview for identification of major depressive disorder (MDD and minor depressive disorder (MIND, according to the Diagnostic and Statistical Manual of Mental Disorders, 4th edition, text revision (DSM-IV-TR, criteria. The Hamilton Depression Rating Scale (HDRS and the Beck Depression Inventory (BDI were also administered to measure depression severity.Results: When considering the whole groups, there were no differences in depressive symptom frequency between PD and CS apart from worthlessness/guilt, and changes in appetite reduced rates in PD. Further, total scores and psychic and somatic subscores of HDRS and BDI did not differ between PD and CS. After we separated PD and CS in those with MDD, MIND, and no depression (NODEP, comparing total scores and psychic/somatic subscores of HDRS and BDI, we found increased total depression severity in NODEP PD and reduced severity of the psychic symptoms of

  12. Unveiling Mercury's Mysteries with BepiColombo - an ESA/JAXA Mission to Explore the Innermost Planet of our Solar System

    Science.gov (United States)

    Benkhoff, J.

    2017-12-01

    providing a highly accurate and comprehensive set of observations of Mercury. The mission has been named in honor of Giuseppe (Bepi) Colombo (1920-1984), who was a brilliant Italian mathematician, who made many significant contributions to planetary research and celestial mechanics.

  13. The potential of classic and specific bioelectrical impedance vector analysis for the assessment of sarcopenia and sarcopenic obesity

    Directory of Open Access Journals (Sweden)

    Marini E

    2012-12-01

    Full Text Available Elisabetta Marini,1 Roberto Buffa,1 Bruno Saragat,1 Alessandra Coin,2 Elena Debora Toffanello,2 Linda Berton,2 Enzo Manzato,2 Giuseppe Sergi21Department of Environmental and Life Sciences, University of Cagliari, Italy; 2Department of Medicine-DIMED, Geriatrics Section, University of Padua, ItalyPurpose: The aim of this paper is to investigate whether bioelectrical impedance vector analysis (BIVA can be a suitable technique for the assessment of sarcopenia. We also investigate the potential use of specific BIVA as an indicator of sarcopenic obesity.Subjects and methods: The sample comprised 207 free-living elderly individuals of both sexes, aged 65 to 93 years. Anthropometric and bioelectrical measurements were taken according to standard criteria. The “classic” and “specific” BIVA procedures, which respectively correct bioelectrical values for body height and body geometry, were used. Dual energy X-ray absorptiometry (DXA was used as the reference method for identifying sarcopenic and obese sarcopenic individuals. Bioelectrical and DXA values were compared using Student’s t-test and Hotelling’s T2 test, as well as Pearson’s correlation coefficient.Results: According to classic BIVA, sarcopenic individuals of both sexes showed higher values of resistance/height (R/H; p < 0.01 and impedance/height (Z/H; p < 0.01, and a lower phase angle (p < 0.01. Similarly, specific BIVA showed significant differences between sarcopenic and nonsarcopenic individuals (men: T2 = 15.7, p < 0.01; women: T2 = 10.7, p < 0.01, with the sarcopenic groups showing a lower specific reactance and phase angle. Phase angle was positively correlated with the skeletal muscle mass index (men: r = 0.52, p < 0.01; women: r = 0.31, p < 0.01. Specific BIVA also recognized bioelectrical differences between sarcopenic and sarcopenic obese men (T2 = 13.4, p < 0.01, mainly due to the higher values of specific R in sarcopenic obese individuals.Conclusion: BIVA detected

  14. A new phase of matter in Oakland

    International Nuclear Information System (INIS)

    Klein, Spencer; Nystrand, Joakim

    2004-01-01

    Recent results from the Relativistic Heavy Ion Collider (RHIC) and the phase diagram of matter at very high energies were the focal points of Quark Matter 2004, held January 10-17, 2004 in the Oakland, California convention center. About 700 participants, including 125 students, from 28 countries gathered for 5 days of plenary and parallel sessions. Besides the scientific discussions, participants enjoyed an afternoon of excursions; choices included visits to San Francisco, the Muir woods, and, of course, a chance to sample Napa Valley wines. There was also a day of introductory lectures for graduate students and a separate afternoon program for 50 local high school teachers. The ''Quark Matter'' conference series has evolved into the premier venue for relativistic heavy ion collisions, and QM2004 was no exception. The 44 plenary and 92 parallel session talks featured a veritable flood of data from STAR (Kai Schweda, LBNL), PHENIX (Tony Frawley, Florida State), PHOBOS (Peter Steinberg, BNL) and BRAHMS (Michael Murray, Kansas), at RHIC. This was accompanied by contributions from HERMES ( Pasquale DiNezza, Frascati) and HERA-B (Joakim Spengler, Heidelberg) and continuing analyses from NA-49 (Marek Gazdzicki, Frankfurt) and NA-57 (Giuseppe Bruno, Bari) at the CERN SPS. The theoretical contributions presented a broad range of models and calculations, from microscopic particle-by-particle simulations to hydrodynamic models that model the bulk behavior using an equation of state. A focus of much discussion was the question ''Have we found the Quark Gluon Plasma (QGP)?'' This search was the prime motivation to build RHIC. Although the RHIC experiments made no formal statement, most conference attendees seemed to feel that the answer was yes. No single measurement makes the case, but the variety of data featured at QM2004 seems most easily explained in the context of a QGP. Some of the signatures included the suppression of high transverse momentum (pT) particles and

  15. Ambulatory blood pressure parameters after canrenone addition to existing treatment regimens with maximum tolerated dose of angiotensin-converting enzyme inhibitors/angiotensin II type 1 receptor blockers plus hydrochlorothiazide in uncontrolled hypertensive patients

    Directory of Open Access Journals (Sweden)

    Guasti L

    2017-08-01

    Full Text Available Luigina Guasti,1,* Giovanni Gaudio,2,* Alessandro Lupi,3 Marinella D’Avino,4 Carla Sala,5,6 Amedeo Mugellini,7 Vito Vulpis,8 Salvatore Felis,9 Riccardo Sarzani,10,11 Massimo Vanasia,12 Pamela Maffioli,7 Giuseppe Derosa7 1Research Center on Dyslipidemia, Internal Medicine 1, University of Insubria, Varese, Italy; 2Internal Medicine Division, Ospedale Angelo Bellini, ASST Valle Olona Somma, Varese, Italy; 3Cardiology Unit, ASL VCO Verbania-Domodossola, Verbania, Italy; 4Unit for the Treatment of Arterial Hypertension, Ospedale Cardarelli, Napoli, Italy; 5Department of Clinical Sciences and Community Health, University of Milan, Milano, Italy; 6Cardiovascular Unit, Fondazione IRCCSS Policlinico, Milano, Italy; 7Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy; 8Unit for the Diagnosis and Treatment of Arterial Hypertension, Department of Internal Medicine, Policlinico di Bari, Bari, Italy; 9Cardiology Unit, Ospedale Garibaldi, Catania, Italy; 10ESH Center of Hypertension, Internal Medicine and Geriatrics, University Politecnica delle Marche, Ancona, Italy; 11IRCCS-INRCA, Ancona, Italy; 12THERABEL GiEnne Pharma, Milano, Italy *These authors contributed equally to this work Background: Blockade of the renin–angiotensin–aldosterone system is a cornerstone in cardiovascular disease prevention and hypertension treatment. The relevance of ambulatory blood pressure monitoring (ABPM has been widely confirmed for both increasing the accuracy of blood pressure (BP measurements, particularly in pharmacological trials, and focusing on 24 h BP prognostic parameters. The aim of this study was to assess the effects of canrenone addition on ambulatory BP in uncontrolled hypertensive patients already treated with the highest tolerated dose of angiotensin-converting enzyme (ACE inhibitors or angiotensin II type 1 receptor (AT1R antagonists plus hydrochlorothiazide (HCT. Methods: ABPM was performed at baseline and after 3

  16. A retrospective case series of ultrasound-guided suprascapular nerve pulsed radiofrequency treatment for hemiplegic shoulder pain in patients with chronic stroke

    Directory of Open Access Journals (Sweden)

    Picelli A

    2018-06-01

    Full Text Available Alessandro Picelli,1,2 Davide Lobba,1 Patrizia Vendramin,3 Giuseppe Castellano,3 Elena Chemello,1 Vittorio Schweiger,4,5 Alvise Martini,4,5 Massimo Parolini,4,5 Marialuisa Gandolfi,1,2 Enrico Polati,4,5 Nicola Smania1,2 1Neuromotor and Cognitive Rehabilitation Research Center, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy; 2Neurorehabilitation Unit, Department of Neurosciences, Hospital Trust of Verona, Verona, Italy; 3Anesthesia, Intensive Care and Pain Therapy Unit, “Girolamo Fracastoro” Hospital, San Bonifacio, Italy; 4Anesthesia and Intensive Care Section, Department of Surgery, Dentistry, Pediatrics and Gynecology, University of Verona, Verona, Italy; 5Pain Therapy Center, Department of Emergency and Intensive Care, Hospital Trust of Verona, Verona, Italy Purpose: Hemiplegic shoulder pain (HSP is the most common pain condition after stroke. Pulsed radiofrequency (PRF treatment of the suprascapular nerve (SSN effectively relieves shoulder pain conditions. To date, there is no study about the effects of PRF treatment for HSP. Thus, our aim was to report on a case series about its use in chronic stroke. Patients and methods: Six chronic stroke patients with HSP (visual analog scale [VAS] score for pain ≥30 mm underwent ultrasound-guided SSN PRF treatment. All were evaluated before treatment and at 4 and 16 weeks of follow-up. The main outcome was VAS score. Secondary outcomes were Modified Ashworth Scale, shoulder passive range of motion (PROM, Disability Assessment Scale (DAS, Fugl-Meyer Assessment, and EuroQol-5 dimension questionnaire (EuroQol-5D scores. Results: As compared with baseline, improvement was observed in the following parameters: VAS for pain (at 4 weeks, P=0.023; at 16 weeks, P=0.023; shoulder PROM for abduction (at 4 weeks, P=0.023; at 16 weeks, P=0.024, flexion (at 4 and 16 weeks, P=0.024, extension (at 4 and 16 weeks, P=0.02, and external rotation (4 and 16

  17. Hemoglobin levels and quality of life in patients with symptomatic chemotherapy-induced anemia: the eAQUA study

    Directory of Open Access Journals (Sweden)

    Mouysset JL

    2016-01-01

    Full Text Available Jean-Loup Mouysset,1 Beata Freier,2 Joan van den Bosch,3 Charles Briac Levaché,4 Alain Bols,5 Hans Werner Tessen,6 Laura Belton,7 G Chet Bohac,8 Jan-Henrik Terwey,9 Giuseppe Tonini101Department of Medical Oncology, Clinique Rambot Provencale, Aix en Provence, France; 2Clinical Oncology, Wojewodzki Szpital Specjalistyczny, Wroclaw, Poland; 3Department of Internal Medicine/Oncology, Albert Schweitzer Ziekenhuis locatie Dordwijk, Dordrecht, the Netherlands; 4Radiotherapy Service, Medical Oncology, Polyclinique Francheville, Périgueux, France; 5Central Pharmacy, AZ Sint-Jan Brugge-Oostende AV, Brugge, Belgium; 6Private Oncology Practice. Goslar, Germany; 7LB Biostatistics, London, UK; 8Clinical Research, Amgen Inc., Thousand Oaks, CA, USA; 9Medical Development – Oncology, Amgen (Europe GmbH, Zug, Switzerland; 10Department of Medical Oncology, Università Campus Bio-Medico, Roma, ItalyPurpose: To assess hemoglobin (Hb outcomes and fatigue-related quality-of-life (QoL (electronic assessment in patients with solid tumors and symptomatic chemotherapy-induced anemia receiving cytotoxic chemotherapy and darbepoetin alfa (DA or another erythropoiesis-stimulating agent according to European indication.Methods: eAQUA was a Phase IV prospective observational study. The primary outcome (assessed in the primary analysis set [PAS]: patients receiving one or more DA dose who had baseline and week 9 assessments for Hb and QoL was the proportion of patients receiving DA having both Hb increases ≥1 g/dL and improved QoL between baseline and week 9. Functional Assessment of Cancer Therapy-Fatigue (FACT-F subscale scores were anchored to fatigue visual analog scale scores to determine the minimally important difference for improved QoL. Overall data/data over time are reported for the full analysis set (patients receiving one or more erythropoiesis-stimulating agent dose, n=1,158; week 9 data (ie, data relating to the primary and secondary outcomes are reported

  18. Selected Abstracts of the 22nd European Neonatal Workshop; Siena (Italy; Carthusia Pontiniani; June 15-18, 2014

    Directory of Open Access Journals (Sweden)

    --- Various Authors

    2014-06-01

    Full Text Available Selected Abstracts of the 22nd European Neonatal Workshop • Siena (Italy • Carthusia Pontiniani • June 15th-18th, 2014Guest Editor: Giuseppe BuonocoreABS 1. Incidence and risk factors of intraventricular hemorrhage (IVH in infants less than 32 weeks of gestation • G. Mitsiakos, A. Papageorgiou; Montreal (Canada ABS 2. Cord blood concentrations of the myokine irisin in fetal macrosomia • D.D. Briana, T. Boutsikou, M. Boutsikou, S. Baka, A. Marmarinos, D. Hassiakos, D. Gourgiotis, A. Malamitsi-Puchner; Athens (Greece ABS 3. Asynchronous chest compressions improve survival in a neonatal piglet model of asphyxial cardiac arrest • N. Iacovidou, A. Aggelina, A. Papalois, A. Douvanas, P. Pliatsika, T. Xanthos; Athens (Greece ABS 4. Human cytomegalovirus (CMV congenital infection. Implementation of a screening program during pregnancy • I. Dorronsoro, M. Lopez-Azorin, M. Caballero, J. García-Flores, M. Recio, A. Pellicer, F. Cabañas; Madrid (Spain ABS 5. Steps forward the BiAR-COH method in autoregulation analysis: assessment of causality • J. Riera, F. Cabañas, J.J. Serrano, M.C. Bravo, P. López-Ortego, L. Sánchez, R. Madero, A. Pellicer; Madrid and Zaragoza (Spain ABS 6. Comparison of delivery room care in three countries: There are many ways of skinning a cat • S. Walter, B. Simma, J. van Vonderen, A.B. te Pas, H. Küster; Göttingen (Germany, Feldkirch (Austria and Leiden (The Netherlands ABS 7. Diaphragmatic function in convalescent preterm infants with chronic lung disease • G. Dimitriou, A. Vervenioti, S. Fouzas, P. Pelekouda; Patras (Greece ABS 8. Stem/progenitors in the newborn kidney: an undiscovered resource to prevent kidney failure later in life? • G. Faa, C. Gerosa, A. Sanna, M. Puddu, D. Fanni, V. Fanos; Cagliari (Italy ABS 9. Placental histological patterns and oxidative stress in the offspring • S. Perrone, S. Negro, M.S. Cori, M.G. Alagna, P. Toti, M.S. Toti, C. Felici, M. Longini, M.L. Tataranno, G

  19. Sky-Radiance Models for Monte Carlo Radiative Transfer Applications

    Science.gov (United States)

    Santos, I.; Dalimonte, D.; Santos, J. P.

    2012-04-01

    differences was afterwards investigated by analyzing how these models vary the sun and sky photon fraction in MC simulations that use the diffuse-to-total irradiance ratio. In this case, differences up to 14% have been found for λ=665 nm and θ*=60°. The study recommendation is then using Lsky models that, like the ZV expression, account for the wavelength dependence of light interaction with atmospheric particles and molecule when initializing MC simulations for ocean color applications, mostly in the case of analyses including the blue region of the visible spectra. Dr. Giuseppe Zibordi, Prof. Pedro Vieira and Tamito Kajiyama are duly acknowledged for valuable discussions. This study has been partiallysupported by ESA under contract n. 12595/09/I-OL with FCT/UNL, Portugal.

  20. The «Natural Hazard WIKISAURUS»: explanation and understanding of natural hazards to build disaster resilience

    Science.gov (United States)

    Rapisardi, Elena; Di Franco, Sabina; Giardino, Marco

    2013-04-01

    In the Internet and Web 2.0 era, the need of information is increased. Moreover, recent major and minor disasters highlighted that information is a crucial element also in emergency management. Informing the population is now the focal point of any civil protection activity and program. Risk perception and social vulnerability become widely discussed issues "when a disaster occurs": a "day-after" approach that should be replaced by a "day-before" one. Is that a cultural problem? Is it a communication issue? As a matter of fact, nowadays academics, experts, institutions are called to be more effective in transferring natural hazards knowledge (technical, operational, historical, social) to the public, for switching from «protection/passivity» (focused on disaster event) to «resilience» (focused on vulnerability). However, this change includes to abandon the "Elites Knowledge" approach and to support "Open Knowledge" and "Open Data" perspectives. Validated scientific information on natural hazards is not yet a common heritage: there are several cases of misleading or inaccurate information published by media. During recent Italian national emergencies [Flash Floods Liguria-Toscana 2011, Earthquake Emilia-Romagna 2012], social media registered people not only asking for news on the disaster event, but also talking trivially about scientific contents on natural hazards. By considering these facts, in the framework of a phD program in Earth Science, a joint team UNITO-NatRisk and CNR-IIA conceived the web project "Natural Hazards Wikisaurus" [NHW], combining two previous experiences: "HyperIspro" - a wiki on civil protection set up by Giuseppe Zamberletti, former Italian minister of Civil Protection - and "Earth Thesaurus", developed by CNR-IIA. The team decided to start from the «words» using both the collaboration of the wiki concept (open and participatory knowledge) and the power of explanation of a thesaurus. Why? Because a word is not enough, as a term has

  1. Safety, efficacy and patient satisfaction with continuous daily administration of levonorgestrel/ethinylestradiol oral contraceptives

    Directory of Open Access Journals (Sweden)

    Giuseppe Benagiano

    2009-04-01

    Full Text Available Giuseppe Benagiano, Sabina Carrara, Valentina FilippiDepartment of Gynaecology and Obstetrics, Sapienza University, Rome, ItalyAbstract: The progestational steroid norgestrel was synthesized and tested between 1960 and 1965 through an international cooperation between Wyeth, USA and Schering, Berlin. It is a mixture of two “enantiomers,” with only one form (designated as levonorgestrel biologically active. When taken orally, it is rapidly absorbed, not subjected to a “first-pass” effect and is approximately 90% bioavailable, with a circulating half-life around 15 hours. Its contraceptive action is exerted at the central (hypothalamic and peripheral (cervical mucus and endometrium levels. Levonorgestrel (LNG, alone or in combination with ethinyl estradiol (EE, is the most widely employed contraceptive progestin: it is used in combined oral contraceptives, progestogen-only pills, long-acting contraceptive implants, intrauterine contraceptive systems and in emergency contraception. It is also the steroid of choice for new oral contraceptive regimens aimed at reducing the frequency of bleeding episodes. This novel approach, already tried more than 30 years ago, gained interest around the year 2000 when surveys of women’s attitudes toward monthly menstrual bleeding started to show a major change: more and more women declared that they would welcome a hormonal contraceptive method that reduced bleeding episodes to 4, 2 or even 1 per year. At this point, while the debate on the significance and “usefulness” of menstruation went on, attention focused on new regimens. The first new modality consisted of changing the 7-day medication-free interval, either shortening it to fewer than 7 days, or by the administration of low-dose estrogens during the interval between packages. Then, continuous administration regimens started to be investigated. This, however, did not happen suddenly, since, in specific situations, doctors had for years

  2. The role of melatonin in mood disorders

    Directory of Open Access Journals (Sweden)

    De Berardis D

    2015-11-01

    Full Text Available Domenico De Berardis,1–3 Laura Orsolini,3–5 Nicola Serroni,1 Gabriella Girinelli,1–3 Felice Iasevoli,3–6 Carmine Tomasetti,3–6 Monica Mazza,3–7 Alessandro Valchera,3–8 Michele Fornaro,9 Giampaolo Perna,10–12 Monica Piersanti,13Marco Di Nicola,14 Marilde Cavuto,15 Giovanni Martinotti,2 Massimo Di Giannantonio21NHS, Department of Mental Health, Psychiatric Service of Diagnosis and Treatment, Hospital "G Mazzini", Teramo, Italy; 2Department of Neuroscience, Imaging and Clinical Science, Chair of Psychiatry, University G d'Annunzio, Chieti, Italy; 3Polyedra, Teramo, Italy; 4United Hospitals, Academic Department of Experimental and Clinical Medicine, Polytechnic University of Marche, Ancona, Italy; 5School of Life and Medical Sciences, University of Hertfordshire, Hatfield, Hertfordshire, UK; 6Laboratory of Molecular Psychiatry and Psychopharmacotherapeutics, Section of Psychiatry, Department of Neuroscience, University School of Medicine Federico II, Naples, Italy; 7Department of Health Sciences, University of L'Aquila, L'Aquila, Italy; 8Villa S Giuseppe Hospital, Hermanas Hospitalarias, Ascoli Piceno, Italy; 9Department of Scienze della Formazione, University of Catania, Catania, Italy; 10Hermanas Hospitalarias, FoRiPsi, Department of Clinical Neurosciences, Villa San Benedetto Menni, Albese con Cassano, Como, Italy; 11Department of Psychiatry and Neuropsychology, University of Maastricht, Maastricht, the Netherlands; 12Department of Psychiatry and Behavioral Sciences, Leonard Miller School of Medicine, University of Miami, Miami, FL, USA; 13Hospital Pharmacy, Hospital G Mazzini, ASL 4 Teramo, Italy; 14Institute of Psychiatry and Psychology, Catholic University of Sacred Heart, Rome, Italy; 15IASM, L'Aquila, ItalyAbstract: Melatonin (N-acetyl-5-methoxytryptamine has been discovered as a hormone secreted by the pineal gland, even though it is also synthetized in various other organs, tissues, and cells. The circadian rhythm of

  3. DHA supplementation for late onset Stargardt disease: NAT-3 study

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    Giuseppe Querques

    2010-06-01

    Full Text Available Giuseppe Querques1, Pascale Benlian1, Bernard Chanu2, Nicolas Leveziel1, Gabriel Coscas1, Gisele Soubrane1, Eric H Souied11Department of Ophthalmology, University of Paris XII, Centre Hospitalier Intercommunal de Creteil, 2Department of Nutrition, University of Paris XII, Hopital Henry Mondor, Creteil, FranceBackground: We analyzed the effects of a docosahexaenoic acid (DHA supplementation in patients affected with late onset Stargardt disease (STGD.Methods: DHA (840 mg/day was given to 20 STGD patients for six months. A complete ophthalmologic examination, including best-corrected visual acuity (BCVA and multifocal electroretinogram (mfERG, was performed at inclusion day 0 (D0 and at month 6 (M6.Results: Overall, no statistical differences have been observed at M6 vs D0 as regards BCVA and mfERG (P > 0.05. Mild Improvement of BCVA and improvement of mfERG was noted in seven/40 eyes of four/20 patients. In the first patient, the peak of the a wave increased from 66 nV/deg² to 75.4 nV/deg² in the right eye (RE and 24.5 nV/deg² to 49.1 nV/deg² in the left eye (LE. The peak of the b wave improved from 122 nV/deg² to 157 nV/deg² in the RE, and 102 nV/deg² to 149 nV/deg² in the LE. In the second patient peaks of the a and b waves respectively increased from 11.8 nV/deg² to 72.1 nV/deg² and 53 nV/deg² to 185 nV/deg² in the RE. In the third patient the peak of the a wave increased from 37 nV/deg² to 43 nV/deg² in the RE, and from 31 nV/deg² to 45 nV/deg² in the LE; the peak of the b wave improved from 70 nV/deg² to 89 nV/deg² in the RE, and from 101 nV/deg² to 108 nV/deg² in the LE. In the fourth patient, the peak of the a wave increased from 39 nV/deg² to 42 nV/deg² in the RE, and from 40 nV/deg² to 43 nV/deg² in the LE; the peak of the b wave improved from 86 nV/deg² to 94 nV/deg² in the RE, and from 87 nV/deg² to 107 nV/deg² in the LE.Conclusion: DHA seems to influence some functional parameters in patients affected with

  4. Archaeological Guidebooks from the Libraries of the Operosi and Their Circle Housed in the Seminary Library in Ljubljana

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    Luka Vidmar

    2005-12-01

    Full Text Available Ljubljana's Academia Operosorum, which helped to regenerate scientific, cultural and artistic activities in the Carniola of the late 17th/early 18th century by introducing the influence of Baroque Italy, was deeply interested in researching and understanding the material and spiritual heritage of Roman antiquity. The Operosi believed that the memory of Emona, the ancient predecessor of Ljubljana, promised a successful development of the modern city, since it symbolically connected Ljubljana with the historical and artistic centre of Europe, the city of Rome. On the one hand, such views on the ancient past were reinforced by Carniolan historians of the previous generation, Janez Ludvik Schönleben and Janez Vajkard Valvasor; on the other, they stemmed from their own observation of Roman monuments, based on their journeys to Italy undertaken immediately after their studies or during their service, and on reading specialised books, bought either on these occasions or in Ljubljana. Many of these books are now housed in the Seminary Library in Ljubljana, as several Operosi donated their private libraries to this new public library, which they helped to establish in 1701. Janez Gregor Dolničar (1655-1719, a Ljubljana lawyer and historian, as well as one of the most prominent members of the Academia Operosorum, owned at least three guidebooks to Rome, written by Pietro Martire Felini and Matteo Mayer and containing detailed descriptions of mainly ancient monuments. His private library also included the architectural treatise by Vitruvius and the hydraulic treatise by Frontinus. Moreover, a few chapters of Dolničar's book on the history of Trieste, written by Father Ireneo della Croce, are devoted to the monuments of ancient Tergeste. Janez Anton Dolničar (1662-1714, the Dean of Ljubljana's Cathedral, owned a guide to Naples, written by Giuseppe Mormile and dealing mostly with ancient ruins in the countryside. Janez Krstnik Preseren (1656-1704, the

  5. Bridging the gap between education and appropriate use of benzodiazepines in psychiatric clinical practice

    Directory of Open Access Journals (Sweden)

    Dell’Osso B

    2015-07-01

    Full Text Available Bernardo Dell’Osso,1,2,* Umberto Albert,3,* Anna Rita Atti,4 Claudia Carmassi,5 Giuseppe Carrà,6 Fiammetta Cosci,7 Valeria Del Vecchio,8 Marco Di Nicola,9 Silvia Ferrari,10 Arianna Goracci,11 Felice Iasevoli,12 Mario Luciano,8 Giovanni Martinotti,13 Maria Giulia Nanni,14 Alessandra Nivoli,15,16 Federica Pinna,17 Nicola Poloni,18 Maurizio Pompili,19 Gaia Sampogna,8 Ilaria Tarricone,20 Sarah Tosato,21 Umberto Volpe,8 Andrea Fiorillo8 1Department of Psychiatry, University of Milan, Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico, Milan, Italy; 2Bipolar Disorders Clinic, Stanford Medical School, Stanford University, CA, USA; 3Rita Levi Montalcini Department of Neuroscience, University of Turin, Torino, 4Department of Biomedical and NeuroMotor Sciences, University of Bologna, Bologna, 5Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy; 6Division of Psychiatry, Faculty of Brain Sciences, University College London, London, UK; 7Department of Health Sciences, University of Florence, Florence, 8Department of Psychiatry, University of Naples SUN, Naples, 9Institute of Psychiatry and Psychology, Catholic University of Sacred Heart, Rome, 10Department of Diagnostic-Clinical Medicine and Public Health, University of Modena and Reggio Emilia, Modena, 11Department of Molecular Medicine and Clinical Department of Mental Health, University of Siena, Siena, 12Department of Neuroscience, Reproductive Sciences and Odontostomatology, University Federico II of Naples, Naples, 13Department of Neuroscience, Imaging, and Clinical Science, University G.d Annunzio, Chieti-Pescara, 14Section of Psychiatry, Department of Biomedical and Specialty Surgical Sciences, University of Ferrara, Ferrara, 15Psychiatric Institute, Department of Clinical and Experimental Medicine, University of Sassari, Sassari, Italy; 16Bipolar Disorder Unit, CIBERSAM, IDIBAPS, Hospital Clinic, University of Barcelona, Barcelona, Spain; 17Department of

  6. VizieR Online Data Catalog: New standards in 18th century astrometry (Lequeux, 2014)

    Science.gov (United States)

    Lequeux, J.

    2014-05-01

    named lacaillefund.dat. La Caille's complete survey of the southern sky (lacaisur.dat): During his stay in Cape Town in 1751-1752, La Caille made the first systematic survey of the sky ever, in the modern sense. 244 stars over 9766. La Caille's catalogue of zodiacal stars (lacaizod.dat): When La Caille returned from his southern expedition in 1754, he undertook the construction of a catalogue of zodiacal stars. Mayer's zodiacal catalogue (mayer.dat): At exactly the same time as La Caille, Tobias Mayer (1723-1762) in Gottingen undertook a similar catalogue of zodiacal stars, using a 6-feet radius mural quadrant made by John Bird (1709-1776). 200 stars over 998. Bradley's stellar catalogue (bradley.dat): James Bradley (1693-1762) is famous for his discovery of aberration and nutation. From 1750 to his death in 1762, he built a large stellar catalogue, from observations first with an old mural sector and after 1753 with the Bird 8-ft mural sector located in Greenwich, where it 215 stars over 3220. Piazzi's stellar catalogue (piazzi.dat): Giuseppe Piazzi (1746-1846) built a large catalogue containing 7646 stars from 1792 to 1813, observed in Palermo with an altazimuthal circle of Jesse Ramsden (1735-1800) can still be seen. 202 stars over 7646. Lalande's stellar catalogue (lalande.dat): L'Histoire celeste francaise de Lalande (Lalande 1801), which contains the unreduced observations of approximately 40,000 stars, is the first very large stellar catalogue. 198 stars over ~45000. (10 data files).

  7. Cost-consequence analysis of sitagliptin versus sulfonylureas as add-on therapy for the treatment of diabetic patients in Italy

    Directory of Open Access Journals (Sweden)

    Lorenzoni V

    2017-11-01

    Full Text Available Valentina Lorenzoni,1 Fabio Baccetti,2 Stefano Genovese,3 Enrico Torre,4 Giuseppe Turchetti1 1Institute of Management, Scuola Superiore Sant’Anna, Pisa, Italy; 2SD Diabetology, ASL Toscana Nordovest, Massa Carrara, Italy; 3Cardiovascular and Metabolic Department, IRCCS Multimedica Sesto San Giovanni, Milan, Italy; 4SSD Endocrinologia, Diabetologia e Malattie metaboliche, ASL 3 Genovese, Genoa, Italy Objective: Diabetes mellitus is a chronic disease related to a significant impact in both epidemiologic and economic terms. In Italy, around 3.6 million people are affected by diabetes and this number is expected to increase significantly in the next few years. As recommended by current national and international guidelines, metformin (Met is prescribed as first-line pharmacological treatment, and many pharmacological alternatives are available for patients uncontrolled with Met monotherapy. Despite the availability of many innovative oral antidiabetic drugs (OADs, such as dipeptidyl peptidase 4 inhibitors (DPP4-i and its first-in-class sitagliptin (SITA, which entered the Italian market in the last 10 years, their usage is consistently lower than traditional drugs such as sulfonylureas (SUs. In fact, due to higher acquisition costs, the prescription of innovative OADs in Italy is restricted to specialist, resulting in a prominent usage of traditional OAD that can be prescribed also by general practitioners (GPs. A cost consequence analysis (CCA was performed in order to compare SITA with SU, as second-line therapy in add-on to Met, in terms of costs and related clinical events over 36 months.Methods: A CCA was conducted on a hypothetical cohort of 100,000 type 2 diabetes mellitus (T2DM patients uncontrolled with Met monotherapy, from both the Italian National Health Service (INHS and societal perspective. Therefore, both direct (drugs, self-monitoring, hypoglycemia, major cardiovascular events [MACEs], and switch to insulin and indirect costs

  8. The role of national regulations in RPAS-based mapping projects in the monitoring of natural hazards that could involve infrastructures: the example of the Val Venosta Railway (Northern Italy - Bolzano).

    Science.gov (United States)

    Gandolfo, Luca; Busnardo, Enrico; Castellarin, Nicola; Canella, Claudio; Canella, Federico; Stabile, Marco; Curci, Francesco; Petrillo, Giovanni

    2016-04-01

    Italy has adopted National Regulations for the use of RPAS in its country's airspace in December 2013, issued by the Italian Civil Aviation Authority (ENAC). Despite the issued regulations, over the past months an increasing number of unauthorized and unsafe operations have been performed and the attention to safety is growing quickly in the public opinion. For this reason "Critical Operations" is permitted only to those RPAS Operators which have received special authorization by ENAC after a very demanding Aeronautical procedure. According to the Regulations, the flight close to-over urban areas, industrial plants, highways and railways, implies that only authorized RPAS Operators may perform such activities. An example of a "Critical" operation were the RPAS flights performed along the Venosta railway line to evaluate the current situation of two areas affected by geological instability and laid the basis for a future high accurate monitoring. The Venosta Valley is located in the western part of South Tyrol (Norhtern Italy). The valley possesses some unique features compared to the entire Alps, the particularly dry climate and the presence of huge alluvional fans, which give rise to different levels of altitude in the valley. From geological point of view, the Venosta Valley is characterized by the presence of the Austroalpine domain. In particular, there are two different geological units in this area: (i) the crystalline schists of the basement, which includes paragneiss, gneiss, granitoid pegmatites, garnet micaschists, quartzites and phyllites. (ii) The Mesozoic coverage divided into various complexes with successions of phyllites, volcanics and magmatiti. The railway line that runs through the Venosta Valley (Merano - Malles) unfolds along a path of 59,8 kilometers and covers an altitude difference of about 700 meters. In particular, three tunnels characterized the first section, including the M. Giuseppe tunnel, which required extensive consolidations both

  9. Radiological response and survival in locally advanced non-small-cell lung cancer patients treated with three-drug induction chemotherapy followed by radical local treatment

    Directory of Open Access Journals (Sweden)

    Bonanno L

    2016-06-01

    Full Text Available Laura Bonanno,1 Giulia Zago,1 Giuseppe Marulli,2 Paola Del Bianco,3 Marco Schiavon,2 Giulia Pasello,1 Valentina Polo,1,4 Fabio Canova,1 Fabrizio Tonetto,5 Lucio Loreggian,5 Federico Rea,2 PierFranco Conte,1,4 Adolfo Favaretto1 1Medical Oncology Unit 2, Veneto Institute of Oncology IOV-IRCCS, 2Thoracic Surgery Department, University of Padova, 3Clinical Trials and Biostatistics Unit, Veneto Institute of Oncology IOV-IRCCS, 4Department of Surgery, Oncology and Gastroenterology, University of Padova, 5Radiotherapy Unit, Veneto Institute of Oncology IOV-IRCCS, Padova, Italy Objectives: If concurrent chemoradiotherapy cannot be performed, induction chemotherapy followed by radical-intent surgical treatment is an acceptable option for non primarily resectable non-small-cell lung cancers (NSCLCs. No markers are available to predict which patients may benefit from local treatment after induction. This exploratory study aims to assess the feasibility and the activity of multimodality treatment, including triple-agent chemotherapy followed by radical surgery and/or radiotherapy in locally advanced NSCLCs. Methods: We retrospectively collected data from locally advanced NSCLCs treated with induction chemotherapy with carboplatin (area under the curve 6, d [day]1, paclitaxel (200 mg/m2, d1, and gemcitabine (1,000 mg/m2 d1, 8 for three to four courses, followed by radical surgery and/or radiotherapy. We analyzed radiological response and toxicity. Estimated progression-free survival (PFS and overall survival (OS were correlated to response, surgery, and clinical features. Results: In all, 58 NSCLCs were included in the study: 40 staged as IIIA, 18 as IIIB (according to TNM Classification of Malignant Tumors–7th edition staging system. A total of 36 (62% patients achieved partial response (PR, and six (10% progressions were recorded. Grade 3–4 hematological toxicity was observed in 36 (62% cases. After chemotherapy, 37 (64% patients underwent surgery

  10. List of participants of the VI School on Cosmic Rays and Astrophysics 17-25 November 2015, Chiapas, Mexico

    International Nuclear Information System (INIS)

    2017-01-01

    Lecturers: 1.- Oscar Saavedra San Martín Università di Torino and Istituto Nazionale di FisicaNucleare (INFN, Italy) 2.- Mario Rodríguez Cahuantzi Benemérita Universidad Autónoma de Puebla (BUAP) 3.- Alberto Carramiñana Instituto Nacional de Astrofísica, Óptica y Electrónica (INAOE, Mexico) 4.- Marco Casolino Rikagaku Kenkyusho, Research Institute (RIKEN, Japan) and INFN (Italy) 5.- Paolo Desiati Wisconsin IceCube Particle Astrophysics Center (WIPAC), Department of Astronomy (Madison, USA) 6.- Paolo Lipari Sezione Roma I dell’ INFN, Universita’ degli Studi “La Sapienza” c/o Istituto di Fisica (Italy) 7.- Juan Carlos Arteaga Velázquez Instituto de Física y Matemáticas of Universidad Michoacana de San Nicolás de Hidalgo (IFM-UMSNH, Mexico) 8.- Karen Salomé Caballero Mora Facultad de Ciencias en Física y Matemáticas, Universidad Autónoma de Chiapas (FCFM-UNACH, Mexico) 9.- Pat Harding Los Alamos National Laboratory (LANL, USA) 10.- Omar Miranda Romagnoli Departamento de Física, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV-Mexico) 11.- Pierluigi Belli INFN Roma Tor Vergata (Italy) 12.- Giuseppe Di Sciascio Departament of Physics (INFN, Italy) 13.- César Álvarez Ochoa FCFM-UNACH, Mexico 14.- Luis Villaseñor IFM-UMSNH, Mexico 15.- Jorge Romo FCFM-UNACH, Mexico 16.- Lukas Nellen Instituto de Ciencias Nucleares, Universidad Nacional Autónoma de México (ICN-UNAM, Mexico) Students: 1.- Ibrahim Torres, INAOE, Mexico 2.-Andrea Correa, Escuela Politécnica Nacional, Ecuador 3.- Humberto Martínez Huerta, CINVESTAV, Mexico 4.- Iván Antonio Cárdenas Muñoz, Universidad de Sonora, Mexico 5.- Juan Antonio Salazar Contreras, Escuela de Ciencias Físicas y Matemáticas, Universidad de San Carlos de Guatemala, USAC, Guatemala 6.- Pravda Linda Flor Cabrera Vogel, USAC, Guatemala 7.- Luis Guillermo García Ordóñez, USAC, Guatemala 8.- Marco Antonio Morales Ovalle, USAC, Guatemala 9.- Joshua Raphael L

  11. PREFACE: DICE 2006—Quantum Mechanics between Decoherence and Determinism

    Science.gov (United States)

    Diósi, Lajos; Elze, Hans-Thomas; Vitiello, Giuseppe

    2007-06-01

    and sponsors generously supported the workshop and their representatives and, in particular, the citizens of Piombino are deeply thanked for the hospitality: G. Anselmi (Sindaco del Comune di Piombino), O. Dell'Omodarme (Assessore alle Culture), A. Tempestini (Assessore alla Pubblica Istruzione), E. Murzi (Assessore al Turismo), A. Falchi (Dirigente dei Servizi Educativi e Culturali), M. Gianfranchi (Responsabile del Servizio Promozione Culturale), T. Ghini (Ufficio Beni Culturali), and L. Grilli, C. Boggero and P. Venturi (Ufficio Cultura), M. Pierulivo (Segreteria del Sindaco), L. Pasquinucci (URP e Comunicazione). Thanks go to Idearte (Cooperativa di Servizi Culturali) and especially to L. Pesce (Vitrium Galleria, Populonia). Funds made available by Universitá di Pisa (Centro Interdisciplinare per lo Studio dei Sistemi Complessi -- CISSC and Domus Galilaeana) and Universitá di Salerno (Dipartimento di Fisica and INFN) are gratefully acknowledged. The research papers presented at the workshop, often incorporating further developments since then, have been edited by L. Diósi, H.-T. Elze and G. Vitiello. They are collected here, essentially following the program of the workshop, however, divided into Invited Lectures and Contributed Papers, respectively. In the name of all participants, we would like to thank G. Douglas (IOP Publishing, Bristol) for his friendly advice and immediate help during the editing process. Lajos Diósi, Hans-Thomas Elze and Giuseppe Vitiello Budapest, Pisa, Salerno, March 2007 1Decoherence and Entropy in Complex Systems ed H-T Elze Lecture Notes in Physics 633 (Berlin: Springer, 2004) 2Proceedings of the Second International Workshop on Decoherence, Information, Complexity and Entropy DICE 2004 ed H-T Elze Braz. J. Phys. 35, 2A and 2B (2005) pp 205 529 freely accessible at: www.sbfisica.org.br/bjp

  12. Skeletal muscle lipid quantification in lean and diabetic subjects using in vivo proton MR spectroscopy

    Directory of Open Access Journals (Sweden)

    Sunil K Valaparla

    2014-03-01

    : Valaparla SK, Boone GRE, Ripley EM, Giuseppe D, Duong TQ, Abdul-Ghani M, Clarke GD. Skeletal muscle lipid quantification in lean and diabetic subjects using in vivo proton MR spectroscopy. Int J Cancer Ther Oncol 2014; 2(2:020239. DOI: 10.14319/ijcto.0202.39

  13. Clinical differences among the elderly admitted to the emergency department for accidental or unexplained falls and syncope

    Directory of Open Access Journals (Sweden)

    Pasqualetti G

    2017-04-01

    Full Text Available Giuseppe Pasqualetti,1 Valeria Calsolaro,1 Giacomo Bini,1 Umberto Dell’Agnello,1 Marco Tuccori,2 Alessandra Marino,2 Alice Capogrosso-Sansone,2 Martina Rafanelli,3 Massimo Santini,4 Eugenio Orsitto,4 Andrea Ungar,3 Corrado Blandizzi,2 Fabio Monzani1 On behalf of the ANCESTRAL-ED study group 1Geriatrics Unit, 2Pharmacology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, 3Syncope Unit, Geriatric and Intensive Care Medicine, AOU Careggi and University of Florence, Florence, 4Emergency Department, University Hospital of Pisa, Pisa, Italy Abstract: It is difficult to distinguish unexplained falls (UFs from accidental falls (AFs or syncope in older people. This study was designed to compare patients referred to the emergency department (ED for AFs, UFs or syncope. Data from a longitudinal study on adverse drug events diagnosed at the ED (ANCESTRAL-ED in older people were analyzed in order to select cases of AF, syncope, or UF. A total of 724 patients (median age: 81.0 [65–105] years, 66.3% female were consecutively admitted to the ED (403 AF, 210 syncope, and 111 UF. The number of psychotropic drugs was the only significant difference in patients with AF versus those with UF (odds ratio [OR] 1.44; 95% confidence interval 1.17–1.77. When comparing AF with syncope, female gender, musculoskeletal diseases, dementia, and systolic blood pressure >110 mmHg emerged as significantly associated with AF (OR 0.40 [0.27–0.58], 0.40 [0.24–0.68], 0.35 [0.14–0.82], and 0.31 [0.20–0.49], respectively, while valvulopathy and the number of antihypertensive drugs were significantly related to syncope (OR 2.51 [1.07–5.90] and 1.24 [1.07–1.44], respectively. Upon comparison of UF and syncope, the number of central nervous system drugs, female gender, musculoskeletal diseases, and SBP >110 mmHg were associated with UF (OR 0.65 [0.50–0.84], 0.52 [0.30–0.89], 0.40 [0.20–0.77], and 0.26 [0.13–0.55], respectively

  14. Prevalence and clinical features associated with bipolar disorder polypharmacy: a systematic review

    Directory of Open Access Journals (Sweden)

    Fornaro M

    2016-03-01

    Full Text Available Michele Fornaro,1 Domenico De Berardis,2 Ann Sarah Koshy,3 Giampaolo Perna,4 Alessandro Valchera,5 Davy Vancampfort,6 Brendon Stubbs7,8 1New York Psychiatric Institute, Columbia University, New York, NY, USA; 2National Health Service, Department of Mental Health, Psychiatric Service of Diagnosis and Treatment, Hospital “G. Mazzini”, Teramo, Italy; 3St. John’s National Academy of Health Sciences, Bangalore, India; 4Department of Clinical Neurosciences, Hermanas Hospitalarias - Villa San Benedetto Menni Hospital, FoRiPsi, 5Hermanas Hospitalarias, FoRiPsi Villa S. Giuseppe Hospital, Ascoli Piceno, Italy; 6Department of Rehabilitation Sciences, KU Leuven, Leuven, Belgium; 7Physiotherapy Department, South London and Maudsley NHS Foundation Trust, 8Health Service and Population Research Department, Institute of Psychiatry, King’s College London, London, UK Background: Uncertainty exists regarding the prevalence and clinical features associated with the practice of polypharmacy in bipolar disorder (BD, warranting a systematic review on the matter.Methods: Three authors independently searched major electronic databases from inception till September 2015. Articles were included that reported either qualitative or quantitative data about the prevalence and clinical features associated with polypharmacy in adult cases of BD.Results: The operative definitions of polypharmacy adopted across varying studies varied, with concomitant use of two or more psychotropic medications or use of four or more psychotropic medications at once being the most common and the most reliable, respectively. Regardless of type or current mood episode polarity of BD, prevalence rates up to 85% and 36% were found using the most permissive (two or more medications at once and the most conservative (four or more operative definitions for polypharmacy, respectively. Point prevalence prescription rates of one or more antidepressant or antipsychotic as part of a polypharmacy

  15. Anteroposterior diameter of the infrarenal abdominal aorta is higher in women with polycystic ovary syndrome

    Directory of Open Access Journals (Sweden)

    Marco Matteo Ciccone

    2009-06-01

    Full Text Available Marco Matteo Ciccone1, Stefano Favale1, Anish Bhuva4, Pietro Scicchitano1, Vito Caragnano1, Cristina Lavopa2, Giovanni De Pergola3, Giuseppe Loverro21Department of Cardiology; 2Department of Gynecology and Obstetrics; 3Section of Internal Medicine, Endocrinology, Andrology, and Metabolic Diseases, University of Bari, DETO, Italy; 4University College of London, London, UKBackground: Women affected by polycystic ovary syndrome (PCOS are known to be at higher risk of cardiovascular disease. The aim of this study was to identify the artery that first is affected by early pre-atherosclerotic changes in PCOS. Methods: Twenty-nine women with PCOS aged 17 to 27 years and 26 healthy nonhyperandrogenic volunteers with regular menses (control women aged 16 to 28 years were enrolled. All PCOS patients were overweight or obese (body mass index [BMI] ≥ 25. Diagnosis of PCOS was performed in line with the 2003 Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. Accordingly, PCOS was defined when at least two of the following three features were present after exclusion of other etiologies: 1 oligomenorrhea and or anovulation; 2 hyperandrogenism and/or hyperandrogenemia; and 3 polycystic ovaries visible at ultrasound. Androgen excess or related disorders were excluded. The intima-media thickness (IMT of common carotid arteries and common femoral arteries and the anteroposterior diameter of the infrarenal abdominal aorta were measured by ultrasound. Lutenizing hormone (LH, follicle-stimulating hormone (FSH, estradiol, total testosterone, androstenedione, and sex hormone-binding globulin (SHBG serum levels were measured between the 3rd and the 6th day of spontaneous or progestin-induced menstrual cycle. Our study was performed in the absence of any medical treatment. Results: Women with PCOS showed a higher LH to FSH ratio (p < 0.01, increased fasting insulin (p < 0.001, total testosterone (p < 0.001, and androstenedione (p < 0.001 levels, and lower

  16. Internet Use and Access, Behavior, Cyberbullying, and Grooming: Results of an Investigative Whole City Survey of Adolescents.

    Science.gov (United States)

    Vismara, Marco Flavio Michele; Toaff, Joseph; Pulvirenti, Giuliana; Settanni, Chiara; Colao, Emma; Lavano, Serena Marianna; Cemicetti, Riccardo; Cotugno, David; Perrotti, Giuseppe; Meschesi, Viviana; Montera, Roberto; Zepponi, Barbara; Rapetto, Umberto; Marotta, Rosa

    2017-08-29

    interviewed teenagers have uploaded pictures or movies of which they felt ashamed; 27.05% (415/1534) have received invitations from people they met on the Internet to meet in real life; and 8.67% (133/1534) have accepted such invitations. The results offer a breakdown of the teenagers' use of the Internet, focusing on how teenagers learn to use and access it while taking into account factors such as parental coaching, schooling, or self-education. It describes how they approach and interact with social networks and how they perceive risks and risky behaviors on the Internet. Information technology must be seen as an instrument and not as a hindrance. For this to happen, parental guidance, schooling, and medical counseling are needed for a sound development of the child in this critical stage. ©Marco Flavio Michele Vismara, Joseph Toaff, Giuliana Pulvirenti, Chiara Settanni, Emma Colao, Serena Marianna Lavano, Riccardo Cemicetti, David Cotugno, Giuseppe Perrotti, Viviana Meschesi, Roberto Montera, Barbara Zepponi, Umberto Rapetto, Rosa Marotta. Originally published in the Interactive Journal of Medical Research (http://www.i-jmr.org/), 29.08.2017.

  17. PhD Dissertations Tesi di dottorato

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    Redazione Reti Medievali (a cura di

    2005-12-01

    Full Text Available Report of PhD Dissertations.Anna Airò La scrittura delle regole. Politica e istituzioni a Taranto nel Quattrocento, Tesi di dottorato di ricerca in Storia medievale, Università degli studi di Firenze, 2005 Pasquale Arfé La Clavis Physicae II (316-529 di Honorius Augustodunensis. Studio ed edizione critica, Tesi di dottorato in Storia della filosofia medievale, Università degli Studi di Napoli "L'Orientale", 2005 Alessandro Azzimonti Scrittura agiografica e strutture di potere nell'Italia centro-settentrionale (X-XII secolo, Tesi di dottorato di ricerca in Forme del sapere storico dal medioevo alla contemporaneità, Università degli Studi di Trieste, 2004 Domenico Cerami Il "Confine conteso". Uomini, istituzioni, culture a Monteveglio tra VIII-XII secolo, Tesi di dottorato di ricerca in Storia Medievale, Università degli studi di Bologna, 2005 Federica Chilà Ostaggi. Uno strumento di pacificazione e governo tra i secoli VIII e XII, Tesi di dottorato di ricerca in Istituzioni, società, religioni dal Tardo Antico alla fine del Medioevo, Università degli Studi di Torino, 2004 Enrico Faini Firenze nei secoli X-XIII: economia e società, Tesi di dottorato di ricerca in Storia medievale, Università degli studi di Firenze, 2005Alessio FioreStrutture e pratiche del potere signorile in area umbro-marchigiana (secoli XI-XIII, Tesi di dottorato ricerca in Storia, Università degli studi di Pisa, 2004Giampaolo FrancesconiTra Riforma, vescovo e clientes. Camaldoli e le società locali (secoli XI-XIII, Tesi di dottorato di ricerca in Storia medievale, Università degli studi di Firenze, 2005 [09/05] Giuseppe Gardoni "Episcopus et potestas". Vescovi e società a Mantova nella prima metà del Duecento, Tesi di dottorato di ricerca in Storia del Cristianesimo e delle Chiese (antichità, medioevo, età moderna, Università degli Studi di Padova, 2005 Nicola Mancassola La gestione delle campagne tra Langobardia e Romània in età carolingia e post

  18. 34th UIT Heat Transfer Conference 2016

    International Nuclear Information System (INIS)

    2017-01-01

    renewed every three years. President, vice-President and secretary cannot be appointed for the same chair more than twice on end. UIT 2016 Steering committee Auditors Vincenzo Naso, President Mario De Salve Giuseppe Vella, Vice-President Marco Spiga Sara Rainieri, Secretary Luca Tagliafico Gian Piero Celata Davide Del Col Paolo Di Marco Alfonso Niro Past-Presidents Past-Secretaries Enrico Lorenzini Sandro Salvigni (First President and Founder) Piero Vigni † Sergio Faggiani † Gian Piero Celata Claudio Pisoni † Paolo Di Marco Gian Piero Celata Distinguished members Honorary members Gaetano Alfano † Arthur E Bergles † Vittorio Betta Michael W Collins † Maurizio Cumo Marino Di Marzo Giovanni Del Tin Frank P Incropera Giovanni De Comelli † Antonio C M Sousa Sergio Faggiani † Enrico Lorenzini Elio Oliveri Claudio Pisoni † Sandro Salvigni Giorgio Sotgia Scientific committee of the 34th UIT heat transfer conference Stefano Piva – Chair - Università degli Studi di Ferrara, Italy Giovanni Sebastiano Barozzi – Università degli Studi di Modena e Reggio Emilia, Italy Gian Paolo Beretta – Università degli Studi di Brescia, Italy Gian Piero Celata – Centro Ricerche ENEA Casaccia, Roma, Italy Michele Ciofalo – Università degli Studi di Palermo, Italy Mario De Salve – Politecnico di Torino, Italy Paolo Di Marco – Università di Pisa, Italy Marco Filippi – Politecnico di Torino, Italy Marco Fossa - Università di Genova, Italy Giovanni Latini – Università Politecnica delle Marche, Italy Enrico Lorenzini – Università degli Studi di Bologna, Italy Rita Mastrullo – Università degli Studi di Napoli Federico II, Italy Oronzio Manca – Seconda Università degli Studi di Napoli, Italy Vincenzo Naso – Università degli Studi di Napoli Federico II, Italy Alfonso Niro – Politecnico di Milano, Italy Enrico Nobile – Università degli Studi di Trieste, Italy Carlo Nonino – Università degli Studi di Udine, Italy Giorgio Pagliarini – Universit

  19. 5th National Congress of the Italian Society of Physiotherapy

    Directory of Open Access Journals (Sweden)

    Alessandro Aina

    2016-10-01

    Full Text Available Table of contents S1 Criteria for exercises selection in subjects with low back pain Alessandro Aina S2 Recent advances in pathophysiology and treatment of myofascial trigger points Marco Barbero S3 Rehabilitation of scapular dyskinesia Barbara Cagnie S4 Musculoskeletal rehabilitation in subjects affected by neurological disorders Elena Castelli S5 Which examination tests suggest the best candidates for manual therapy Chad Cook S6 Case study: the role of the measurements for the identification of targets and guidance of the treatment Silvano Ferrari S7 Assessment of joint mobility: state of the art Andrea Foglia, Paolo Bizzarri S8 Core stabilization exercises in the treatment of urinary incontinence Donatella Giraudo S9 Preventing surgical subacromial decompression through rotator cuff rehabilitation Chris Littlewood S10 Methodological aspects of Clinical Prediction Rules in the rehabilitation of Low Back Pain Paolo Pillastrini S11 Interpretability of outcome measures in musculoskeletal rehabilitation Daniele Piscitelli S12 Conservative treatment of the misalignment of the spine: state of the art and perspectives Michele Romano S13 Balance training in subjects with musculoskeletal disorders Andrea Tettamanti S14 Dosage of manual therapy: principles for clinical practice Carla Vanti S15 Are there speed limits in post-surgery lower limb rehabilitation? Stefano Vercelli S16 Classification of predominant neuropathic, nociceptive or central sensation pain Lennard Voogt P1 A wearable proprioceptive stabilizer (Equistasi® for rehabilitation of balance disorders in multiple sclerosis patients: preliminary results of a randomized, double-blind, versus placebo controlled study Aceto Maria, Spina Emanuele, Paone Paolo, Silvestre Francesco, Carotenuto Antonio, Cerillo Ilaria, Orefice Giuseppe P2 Effect of repeated neck retraction movements on strength and EMG activity of the upper limbs, range of motion and cervical posture Bassi Raffaele, Fiorito Serena

  20. Selected Abstracts of the 1st Congress of joint European Neonatal Societies (jENS 2015; Budapest (Hungary; September 16-20, 2015; Session “Pharmacology”

    Directory of Open Access Journals (Sweden)

    Various Authors

    2015-09-01

    Full Text Available Selected Abstracts of the 1st Congress of joint European Neonatal Societies (jENS 2015; Budapest (Hungary; September 16-20, 2015ORGANIZING INSTITUTIONSEuropean Society for Neonatology (ESN, European Society for Paediatric Research (ESPR, Union of European Neonatal & Perinatal Societies (UENPS, European Foundation for the Care of Newborn Infants (EFCNI, with the local host of Hungarian Society of Perinatology and Obstetric Anesthesiology, Hungarian Society of Perinatology (MPT, supported by Council of International Neonatal Nurses (COINN, organizing secretariat MCA Scientific EventsPROGRAMME COMMITTEEArtúr Beke (Hungarian Society, Morten Breindahl (ESN, Giuseppe Buonocore (UENPS, Pierre Gressens (ESPR, Silke Mader (EFCNI, Manuel Sánchez Luna (UENPS, Miklós Szabó (Hungarian Society of Perinatology, Luc Zimmermann (ESPR Session “Pharmacology”ABS 1. BABY SKIN CARE PRODUCTS • P. Doro, R. Abraham, D. Agoston, J. Balog, R.Z. CsomaABS 2. MATHEMATICAL MODELING TO PREDICT IN-HOSPITAL NATURAL WEIGHT CHANGES IN TERM NEONATES • S. Kasser, M. Wilbaux, C. De Angelis, H. Rickenbacher, N. Klarer, J.N. Van Den Anker, M. Pfister, S. WellmannABS 3. IMPROVING PARENTERAL NUTRITION IN THE NEONATE – A PRACTICAL GUIDELINE • H. Reigstad, D. Moster, I. Grønlie, A. BlystadABS 4. INVOLUTION OF RETINOPATHY OF PREMATURITY AND NEURODEVELOPMENTAL OUTCOME AFTER BEVACIZUMAB TREATMENT • Y.-S. Chang, P.-N. Tsao, C.-Y. Chen, H.-C. Chou, W.-S. Hsieh, P.-T. YehABS 5. RELATIONSHIP BETWEEN ADVERSE DRUG REACTIONS AND OFF-LABEL/UNLICENSED DRUG USE IN HOSPITALISED CHILDREN. EREMI STUDY • K.A. Nguyen, Y. Mimouni, A. Lajoinie, N. Paret, S. Malik, L. El-Amrani, L. Milliat-Guittard, C. Carcel, A. Portefaix, A.M. Schott, T. Vial, B. KassaiABS 6. A SYSTEMATIC REVIEW OF OFF-LABEL AND UNLICENSED DRUGS USE AND ADVERSE DRUG REACTIONS IN HOSPITALIZED CHILDREN • N. David, K.A. Nguyen, Y. Mimouni, A. Lajoinie, S. Malik, B. KassaiABS 7. EFFICACY AND SAFETY OF PROPOFOL SEDATION

  1. PREFACE: DICE 2008 - From Quantum Mechanics through Complexity to Spacetime: the role of emergent dynamical structures

    Science.gov (United States)

    Diósi, Lajos; Elze, Hans-Thomas; Fronzoni, Leone; Halliwell, Jonathan; Vitiello, Giuseppe

    2009-07-01

    (Direttore), G Mannari (Programmazione). Special thanks go to G Mannari for her advice and great help in all the many practical matters that had to be dealt with, in order to run the meeting at Castello Pasquini smoothly. Funds made available by Universitá di Pisa, by Domus Galilaeana (Pisa), Centro Interdisciplinare per lo Studio dei Sistemi Complessi - CISSC (Pisa), Dipartimento di Matematica e Informatica (Universitá di Salerno), Istituto Italiano per gli Studi Filosofici - IISF (Napoli), and by IOP Publishing (Bristol) are gratefully acknowledged. Last but not least, special thanks go to L Pesce (Vitrium Galleria, Populonia) for her artwork (``Art and Science'') displayed during the conference at Castello Pasquini. The research papers presented at the workshop, often incorporating further developments since then, or presenting original new work, have been edited by L Diósi, H-T Elze, L Fronzoni, J J Halliwell and G Vitiello, with major assistance from J Yearsley (London), which we gratefully acknowledge. They are collected here, essentially following the program of the workshop, however, divided into Invited Lectures (we regret that lectures by E Arimondo, N Gisin, and W Schleich could not be reproduced here) and Contributed Papers, respectively. In the name of all participants, we would like to thank Dr J Schwarz and G Douglas (IOP Publishing, Bristol), and their collaborators, for friendly advice, always immediate help during the editing process, and for their efforts making the Journal of Physics: Conference Series available to all. Budapest, Pisa, London and Salerno, May 2009 Lajos Diósi, Hans-Thomas Elze, Leone Fronzoni, Jonathan Halliwell and Giuseppe Vitiello

  2. Time since plantation is the most important determining factor for soil erosion rates in vineyards. A case study in the valley of Les Alcusses valley, Eastern Spain

    Science.gov (United States)

    Rodrígo Comino, Jesús; Keesstra, Saskia; Novara, Agata; García Díaz, Andrés; Jordán, Antonio; Brevik, Eric C.; Cerdà, Artemi

    2017-04-01

    simulated rainfall events. Soil Res, 54, 2, 154-165 DOI: 10.1071/SR15092 Keesstra S, Pereira P, Novara A, Brevik EC, Azorin-Molina C, Parras-Alcántara L, Jordán A, Cerdà A. 2016. Effects of soil management techniques on soil water erosion in apricot orchards. Science of the Total Environment 551-552: 357-366. DOI: 10.1016/j.scitotenv.2016.01.182 Novara, A., A. Cerdà, D. Carmelo, L. P. Giuseppe, S. Antonino, and G. Luciano. 2015. Effectiveness of Carbon Isotopic Signature for Estimating Soil Erosion and Deposition Rates in Sicilian Vineyards. Soil and Tillage Research 152: 1-7. doi:10.1016/j.still.2015.03.010. Novara, A., L. Gristina, F. Guaitoli, A. Santoro, and A. Cerdà. 2013. Managing Soil Nitrate with Cover Crops and Buffer Strips in Sicilian Vineyards. Solid Earth 4 (2): 255-262. doi:10.5194/se-4-255-2013. Novara, A., L. Gristina, S. S. Saladino, A. Santoro, and A. Cerdà. 2011. Soil Erosion Assessment on Tillage and Alternative Soil Managements in a Sicilian Vineyard. Soil and Tillage Research 117: 140-147. doi:10.1016/j.still.2011.09.007. Prosdocimi, M., A. Cerdà, and P. Tarolli. 2016a. Soil Water Erosion on Mediterranean Vineyards: A Review. Catena 141: 1-21. doi:10.1016/j.catena.2016.02.010. Prosdocimi, M., A. Jordán, P. Tarolli, S. Keesstra, A. Novara, and A. Cerdà. 2016b. The Immediate Effectiveness of Barley Straw Mulch in Reducing Soil Erodibility and Surface Runoff Generation in Mediterranean Vineyards. Science of the Total Environment 547: 323-330. doi:10.1016/j.scitotenv.2015.12.076. Rodrigo Comino J, Iserloh T, Morvan X, Malam Issa O, Naisse C, Keesstra SD, Cerdà A, Prosdocimi M, Arnáez J, Lasanta T, Ramos MC, Marqués MJ, Ruiz Colmenero M, Bienes R, Ruiz Sinoga JD, Seeger M, Ries JB 2016a. Soil Erosion Processes in European Vineyards: A Qualitative Comparison of Rainfall Simulation Measurements in Germany, Spain and France. Hydrology, 3 (1), 6; doi:10.3390/hydrology3010006 Rodrigo Comino, J., Iserloh, T., Lassu, T., Cerdà, A., Keesstra, S

  3. Something going on in Milan: a review of the 4th International PhD Student Cancer Conference.

    Science.gov (United States)

    Segré, C

    2010-01-01

    Maria Sarra Ferraris), due to the high scientific level of the abstracts submitted. In the end, 26 top students were chosen to give a 15-min oral presentation in one of eight sessions: Development & Differentiation, Cell Migration, Immunology & Cancer, Modelling & Large Scale approaches, Genome Instability, Signal Transduction, Cancer Genetics & Drug Resistance, Stem Cells in Biology and Cancer.The scientific programme was further enriched by two scientific special sessions, held by Professor Pier Paolo di Fiore and Dr Giuseppe Testa, Principal Investigators at the IFOM-IEO-Campus and by a bioethical round table on human embryonic stem cell research moderated by Silvia Camporesi, a senior PhD student in the SEMM PhD Programme 'Foundation of Life Science and their Bioethical Consequences'.ON TOP OF EVERYTHING, WE HAD THE PLEASURE OF INVITING, AS KEYNOTE SPEAKERS, TWO LEADING EUROPEAN SCIENTISTS IN THE FIELDS OF CANCER INVASION AND BIOLOGY OF STEM CELLS, RESPECTIVELY: Dr Peter Friedl from The Nijmegen Centre for Molecular Life (The Netherlands) and Professor Andreas Trumpp from The Heidelberg Institute for Stem Cell Technology and Experimental Medicine (Heidelberg).All the student talks have distinguished themselves for the impressive quality of the science; an encouraging evidence of the high profile level of research carried out in Europe. It would be beyond the purposes of this report to summarise all 26 talks, which touched many different and specific topics. For further information, the Conference Abstract book with all the scientific content is available on the conference Web site (http://www.semm.it/events_researchPast.php). In what follows, the special sessions and the keynote lectures will be discussed in detail.

  4. INTRODUCTION: New trends in simulating colloids and self-assembling systems New trends in simulating colloids and self-assembling systems

    Science.gov (United States)

    Foffi, Giuseppe; Kahl, Gerhard

    2010-03-01

    University Of Oxford and Athanassios Panagiotopoulos—University Of Princeton) focused on the remarkable ability of colloidal systems to self-organize in well-defined composite objects. New simulation techniques and theoretical approaches were presented and discussed that offer a deeper understanding of self-assembly phenomena in colloidal physics and, eventually to uncover design rules for self-assembly. Particular emphasis was put on an emerging new class of colloidal particles, so-called patchy colloids. The second workshop, entitled 'New Trends in Simulating Colloids: From Models to Applications', (organized by Giuseppe Foffi—Ecole Polytechnique Fédérale De Lausanne, Gerhard Kahl—Vienna Technical University and Richard Vink—Georg-August-Universität Göttingen) focused on new methodological devices in theoretical and simulation approaches that provided a more profound insight in colloidal physics in general. A large variety of theoretical tools, ranging from different simulation techniques over classical density functional theory to efficient optimization techniques were presented. For details about the tools presented in both workshops we refer the reader to the contributions of this special issue. The 'round table' discussion meetings were highly useful in providing an overview of yet unsolved problems and to point out directions for future work. From the phenomenological point of view, among those are the question on the relevance of hydrodynamic interactions, the problem whether to treat solvents in an explicit or implicit way, or the relevance of multibody interactions, to name but a few. With respect to the methods it was agreed that future developments on dynamic Monte Carlo simulations or on rare events and multiscale techniques are urgently required. The presence of the experimentalists was also of great help in focusing attention on the systems that are going to represent the scientific challenges in the next years. It was interesting that while new

  5. Controllable Quantum States Mesoscopic Superconductivity and Spintronics (MS+S2006)

    Science.gov (United States)

    Takayanagi, Hideaki; Nitta, Junsaku; Nakano, Hayato

    2008-10-01

    Mesoscopic effects in superconductors. Tunneling measurements of charge imbalance of non-equilibrium superconductors / R. Yagi. Influence of magnetic impurities on Josephson current in SNS junctions / T. Yokoyama. Nonlinear response and observable signatures of equilibrium entanglement / A. M. Zagoskin. Stimulated Raman adiabatic passage with a Cooper pair box / Giuseppe Falci. Crossed Andreev reflection-induced giant negative magnetoresistance / Francesco Giazotto -- Quantum modulation of superconducting junctions. Adiabatic pumping through a Josephson weak link / Fabio Taddei. Squeezing of superconducting qubits / Kazutomu Shiokawa. Detection of Berrys phases in flux qubits with coherent pulses / D. N. Zheng. Probing entanglement in the system of coupled Josephson qubits / A. S. Kiyko. Josephson junction with tunable damping using quasi-particle injection / Ryuta Yagi. Macroscopic quantum coherence in rf-SQUIDs / Alexey V. Ustinov. Bloch oscillations in a Josephson circuit / D. Esteve. Manipulation of magnetization in nonequilibrium superconducting nanostructures / F. Giazotto -- Superconducting qubits. Decoherence and Rabi oscillations in a qubit coupled to a quantum two-level system / Sahel Ashhab. Phase-coupled flux qubits: CNOT operation, controllable coupling and entanglement / Mun Dae Kim. Characteristics of a switchable superconducting flux transformer with a DC-SQUID / Yoshihiro Shimazu. Characterization of adiabatic noise in charge-based coherent nanodevices / E. Paladino -- Unconventional superconductors. Threshold temperatures of zero-bias conductance peak and zero-bias conductance dip in diffusive normal metal/superconductor junctions / Iduru Shigeta. Tunneling conductance in 2DEG/S junctions in the presence of Rashba spin-orbit coupling / T. Yokoyama. Theory of charge transport in diffusive ferromagnet/p-wave superconductor junctions / T. Yokoyama. Theory of enhanced proximity effect by the exchange field in FS bilayers / T. Yokoyama. Theory of

  6. PREFACE: DICE 2012 : Spacetime Matter Quantum Mechanics - from the Planck scale to emergent phenomena

    Science.gov (United States)

    Diósi, Lajos; Elze, Hans-Thomas; Fronzoni, Leone; Halliwell, Jonathan; Prati, Enrico; Vitiello, Giuseppe; Yearsley, James

    2013-06-01

    during the conference. The papers submitted in the wake of the conference have been edited by L Diósi, H-T Elze, L Fronzoni, J J Halliwell, E Prati, G Vitiello and J Yearsley. The proceedings follow essentially the order of presentation during the conference, separating, however, invited lectures and contributed papers6. In the name of all participants, we would like to thank S Toms with her collaborators at IOP Publishing (Bristol) for friendly advice and most valuable immediate help during the editing process and, especially, for their continuing efforts to make the Journal of Physics: Conference Series available to all. Budapest, Pisa, London, Milano, Salerno, Cambridge, April 2013 Lajos Diósi, Hans-Thomas Elze, Leone Fronzoni, Jonathan Halliwell, Enrico Prati, Giuseppe Vitiello and James Yearsley 1 Decoherence and Entropy in Complex Systems ed H-T Elze Lecture Notes in Physics 633 (Berlin: Springer, 2004) 2 Proceedings of the Second International Workshop on Decoherence, Information, Complexity and Entropy - DICE 2004 ed H-T Elze Braz. Journ. Phys. 35 A & 2B (2005) pp 205-529 free access at: www.sbfisica.org.br/bjp 3 Proceedings of the Third International Workshop on Decoherence, Information, Complexity and Entropy - DICE 2006 eds H-T Elze, L Diósi and G Vitiello Journal of Physics: Conference Series 67 (2007); free access at: www.iop.org/EJ/toc/1742-6596/67/1 4 Proceedings of the Fourth International Workshop on Decoherence, Information, Complexity and Entropy - DICE 2008> eds H-T Elze, L Diósi, L Fronzoni, J J Halliwell and G Vitiello Journal of Physics: Conference Series 174 (2009); free access at: http://www.iop.org/EJ/toc/1742-6596/174/1 5 Proceedings of the Fifth International Workshop on Decoherence, Information, Complexity and Entropy - DICE 2010 eds H-T Elze, L Diósi, L Fronzoni, J J Halliwell, E Prati, G Vitiello and J Yearsley Journal of Physics: Conference Series 306 (2011); free access at: http://iopscience.iop.org/1742-6596/306/1 6 We regret that

  7. List of Participants

    Science.gov (United States)

    2007-11-01

    Physique Théorique, École Polytechnique, Palaiseau Diego Mansi Università Degli Studi di Milano Matteo Marescotti Università del Piemonte Orientale, Alessandria Alberto Mariotti Università di Milano-Bicocca Raffaele Marotta Istituto Nazionale di Fisica Nucleare, Napoli Alessio Marrani Istituto Nazionale di Fisica Nucleare and LNF, Firenze Luca Martucci Instituto de Física Teórica, Madrid and Katholieke Universiteit Leuven David Mateos University of California, Santa Barbara Andrea Mauri Università di Milano Liuba Mazzanti Università di Milano-Bicocca Patrick Meessen Instituto de Física Teórica, Universidad Autónoma de Madrid Lotta Mether Helsinki Institute of Physics Rene Meyer Max-Planck-Institut für Physik, München Giuseppe Milanesi SISSA, Trieste Cesar Miquel-Espanya Universitat de Valencia and Instituto de Física Corpuscular, Valencia Alexander Monin Institute for Theoretical and Experimental Physics (ITEP), Moscow and Moscow State University (MSU) Samuel Monnier Université de Genève Sergio Montero Instituto de Física Teórica, Madrid Nicola Mori Università di Firenze Alexander Marcel Morisse University of California, Santa Cruz Sebastian Moster Max-Planck-Institut für Physik, München Adele Nasti Queen Mary, University of London Vasilis Niarchos École Polytechnique, Palaiseau Emil Nissimov Institute for Nuclear Research and Nuclear Energy, Sofia Francesco Nitti École Polytechnique, Palaiseau Eoin O'Colgain Imperial College, London Niels Obers Niels Bohr Institute, København Rodrigo Olea Università Degli Studi di Milano Marta Orselli Niels Bohr Institute, København Enrico PajerLudwig-Maximilians-Universität, München Eran PaltiOxford University Georgios PapathanasiouBrown University, Providence, RI Angel ParedesCentre de Physique Théorique, École Polytechnique, Palaiseau Jeong-Hyuck ParkMax-Planck-Institut für Physik, München Sara PasquettiUniversità di Parma Silvia PenatiUniversità di Milano-Bicocca Igor PesandoUniversità di Torino

  8. AAS 228: Day 4

    Science.gov (United States)

    Kohler, Susanna

    2016-06-01

    Editors Note: Lastweek we were at the 228th AAS Meeting in San Diego, CA. Here is a final post aboutselectedevents on the last day of the meeting, written by authors fromastrobites.com, a grad-student collaborative project with which we recently announced a new partnership! Starting in July,keep an eye out for astrobites postsat AAS Nova in between Highlights(i.e., on Tuesdays and Thursdays).Were excited to be working together to bring you more recent astronomy research from AAS journals!Extrasolar Planets: Detection (by Leonardo dos Santos)Thursdays first session on exoplanets was about detecting these distant worlds, and the opening talk was given by Robert Siverd (Las Cumbres Observatory). He describes the NRES, a network of spectrographs that will look for exoplanets using the radial velocity method. One of the coolest aspects of this instrument is that it will feature an on the fly scheduling system that will perform observations as efficiently as possible. The spectrograph is still being tested, but a unit will be deployed at CTIO later this year.@lcogt contracted by @NASA_TESS for follow up of their candidates. #aas228 Jessie Christiansen (@aussiastronomer) June 16, 2016Measuring the depths of transits and eclipses in Spitzer has been problematic in the past, since the Spitzer instrument IRAC (InfraRed Array Camera) has a non-uniform response in its detectors pixels. But, as reported by James Ingalls (Spitzer Science Center, Caltech), observers are circumventing this issue by using what they call the staring mode (avoiding large pointing jumps) and an algorithm to pick sweet spot pixels. Moreover, the results from the IRAC Data Challenge are helping to better understand its behavior. Giuseppe Morello (University College London), on the other hand, explained how his research group gets rid of instrumental effects from IRAC using machine learning. This method removes systematics from exoplanet transit data no matter if the noise source is from an instrument or

  9. Impact landing ends SMART-1 mission to the Moon

    Science.gov (United States)

    2006-09-01

    lunar science at a time when the exploration of the Moon is once again getting the world’s interest” said Bernard Foing, ESA SMART-1 Project Scientist. “The measurements by SMART-1 call into question the theories concerning the Moon’s violent origin and evolution,” he added. The Moon may have formed from the impact of a Mars-size asteroid with the Earth 4500 million years ago. “SMART-1 has mapped large and small impact craters, studied the volcanic and tectonic processes that shaped the Moon, unveiled the mysterious poles, and investigated sites for future exploration,” Foing concluded. “ESA’s decision to extend the SMART-1 scientific mission by a further year ( it was initially planned to last only six months around the Moon) allowed the instrument scientists to extensively use a number of innovative observing modes at the Moon,” added Gerhard Schwehm, ESA’s SMART-1 Mission Manager. In addition to plain nadir observations (looking down on the ‘vertical’ line for lunar surveys), they included targeted observations, moon-spot pointing and ‘push-broom’ observations (a technique SMART-1 used to obtain colour images). “This was tough work for the mission planners, but the lunar data archive we are now building is truly impressive.” “SMART-1 has been an enormous success also from a technological point of view,” said Giuseppe Racca, ESA SMART-1 Project Manager. The major goal of the mission was to test an ion engine (solar electric propulsion) in space for the first time for interplanetary travel, and capture a spacecraft into orbit around another celestial body, in combination with gravity assist manoeuvres. SMART-1 also tested future deep-space communication techniques for spacecraft, techniques to achieve autonomous spacecraft navigation, and miniaturised scientific instruments, used for the first time around the Moon. “It is a great satisfaction to see how well the mission achieved its technological objectives, and did great lunar

  10. Soil erosion and degradation in Mediterranean Type Ecosystems. The Soil Erosion and Degradation Research Group (SEDER) approach and findings

    Science.gov (United States)

    Cerdà, Artemi; Keesstra, Saskia; Pulido, Manuel; Jordán, Antonio; Novara, Agata; Giménez-Morera, Antonio; Borja, Manuel Esteban Lucas; Francisco Martínez-Murillo, Juan; Rodrigo-Comino, Jesús; Pereira, Paulo; Nadal-Romero, Estela; Taguas, Tani; Úbeda, Xavier; Brevik, Eric C.; Tarolli, Paolo; Bagarello, Vicenzo; Parras Alcantara, Luis; Muñoz-Rojas, Miriam; Oliva, Marc; di Prima, Simone

    2017-04-01

    .1016/j.earscirev.2014.07.005 Bodí, M. B., Martin, D. A., Balfour, V. N., Santín, C., Doerr, S. H., Pereira, P., . . . Mataix-Solera, J. (2014). Wildland fire ash: Production, composition and eco-hydro-geomorphic effects. Earth-Science Reviews, 130, 103-127. doi:10.1016/j.earscirev.2013.12.007 Cerdà, A., González-Pelayo, O., Giménez-Morera, A., Jordán, A., Pereira, P., Novara, A., . . . Ritsema, C. J. (2016). Use of barley straw residues to avoid high erosion and runoff rates on persimmon plantations in eastern spain under low frequency-high magnitude simulated rainfall events. Soil Research, 54(2), 154-165. doi:10.1071/SR15092 Cerdà, A., Lavee, H., Romero-Díaz, A., Hooke, J., & Montanarella, L. (2010). Preface: Soil erosion and degradation in mediterranean type ecosystems. Land Degradation and Development, 21(2), 71-74. doi:10.1002/ldr.968 Dlapa, P., Bodí, M. B., Mataix-Solera, J., Cerdà, A., & Doerr, S. H. (2015). Organic matter and wettability characteristics of wildfire ash from mediterranean conifer forests. Catena, 135, 369-376. doi:10.1016/j.catena.2014.06.018 Keesstra, S., Pereira, P., Novara, A., Brevik, E. C., Azorin-Molina, C., Parras-Alcántara, L., . . . Cerdà, A. (2016). Effects of soil management techniques on soil water erosion in apricot orchards. Science of the Total Environment, 551-552, 357-366. doi:10.1016/j.scitotenv.2016.01.182 Lucas-Borja, M. E., Hedo, J., Cerdá, A., Candel-Pérez, D., & Viñegla, B. (2016). Unravelling the importance of forest age stand and forest structure driving microbiological soil properties, enzymatic activities and soil nutrients content in mediterranean spanish black pine(pinus nigra ar. ssp. salzmannii) forest. Science of the Total Environment, 562, 145-154. doi:10.1016/j.scitotenv.2016.03.160 Novara, A., Cerdà, A., Carmelo, D., Giuseppe, L. P., Antonino, S., & Luciano, G. (2015). Effectiveness of carbon isotopic signature for estimating soil erosion and deposition rates in sicilian vineyards. Soil and

  11. Selected Abstracts of the 1st Congress of joint European Neonatal Societies (jENS 2015; Budapest (Hungary; September 16-20, 2015; Session “Epidemiology”

    Directory of Open Access Journals (Sweden)

    Various Authors

    2015-09-01

    Full Text Available Selected Abstracts of the 1st Congress of joint European Neonatal Societies (jENS 2015; Budapest (Hungary; September 16-20, 2015ORGANIZING INSTITUTIONSEuropean Society for Neonatology (ESN, European Society for Paediatric Research (ESPR, Union of European Neonatal & Perinatal Societies (UENPS, European Foundation for the Care of Newborn Infants (EFCNI, with the local host of Hungarian Society of Perinatology and Obstetric Anesthesiology, Hungarian Society of Perinatology (MPT, supported by Council of International Neonatal Nurses (COINN, organizing secretariat MCA Scientific EventsPROGRAMME COMMITTEEArtúr Beke (Hungarian Society, Morten Breindahl (ESN, Giuseppe Buonocore (UENPS, Pierre Gressens (ESPR, Silke Mader (EFCNI, Manuel Sánchez Luna (UENPS, Miklós Szabó (Hungarian Society of Perinatology, Luc Zimmermann (ESPR Session “Epidemiology”ABS 1. A PERFORMANCE INDICATOR FOR THE PROLONGATION OF GESTATIONAL AGE • N. LackABS 2. LATE PRETERM NEONATES AND CAUSES OF ADMISSION TO THE NICU • S. Arayici, G. Kadioglu Simsek, B. Say, E. Alyamac Dizdar, N. Uras, F.E. Canpolat, S.S. OguzABS 3. INCIDENCE AND OUTCOMES OF METABOLIC DISORDERS IN VERY PRETERM INFANTS • O. Dobush, D. Dobryanskyy, Z. Salabay, O. Detsyk, O. Novikova, Y. KuzminovABS 4. MATERNAL FACTORS INFLUENCE INFANT’S VITAMIN D STATUS • H. Hauta-alus, E. Holmlund-Suila, M. Enlund-Cerullo, J. Rosendahl, S. Valkama, O. Helve, H-M. Surcel, O. Mäkitie, S. Andersson, H. ViljakainenABS 5. THE HIGH PREVALENCE OF VITAMIN D DEFICIENCY IN A LARGE NUMBER OF PREGNANT WOMEN AND RELATED FACTORS IN ANKARA, TURKEY • G. Kadioglu Simsek, F. E. Canpolat, S. Arayici, G. Kanmaz Kutman, H.I. Yakut, Ö. Moraloğlu, B. ÖzkanABS 6. SNAPPE-II: A VALUABLE PREDICTOR OF ADVERSE OUTCOMES IN PREMATURITY • P. Costa-Reis, R. Monteiro, M. Abrantes, P. Costa, A. Graça, C. MonizABS 7. THE ASSOCIATION BETWEEN MATERNAL AND FETAL 25OHD AND INFANT SIZE AND ADIPOSITY AT BIRTH, 6 MONTHS AND 2 YEARS OF AGE • M

  12. SMART-1: the first spacecraft of the future

    Science.gov (United States)

    2003-09-01

    This is the first of a series of missions designed to test key technologies for future spacecraft —SMART stands for 'Small Missions for Advanced Research and Technology'. In the case of SMART-1, the two main new technologies to be tested are a new 'solar-electric propulsion' system and miniaturised spacecraft and instrumentation. Together, these technologies make up a spacecraft with revolutionary qualities: smaller, lighter, capable of carrying more scientific instruments, greater fuel efficiency. All of which also considerably reduces the cost of the mission. So, the idea behind SMART-1 is to pioneer a futuristic philosophy, the motto of which could be: 'more science for less money'. Even though it is the first of a kind, SMART-1 has been developed in less than four years, and at about a fifth of the cost of a major science mission for ESA: only 110 million euros. That includes the launch, the operations and a dozen scientific experiments. This was achieved partly by using new management methods — such as working with smaller teams both within ESA and in the industry — and partly because of some of the new features inherent in SMART-1, such as the miniaturisation and novel design. Giuseppe Racca, SMART-1 Project Manager, explains: "What has been our trick? First, a short development period in itself means less money. But also, with its small size — which was a requirement of the mission because we are testing miniaturised hardware — the spacecraft is able to 'share' a commercial Ariane flight with two other passengers. Besides, since we were not constrained by any existing design or heritage, we could be more innovative and elegant in our architecture. For example, the new SMART-1 electrical architecture has enabled us to simplify the system tests considerably." SMART-1 could almost be a toy spacecraft — it weighs only 367 kilograms and fits into a cube just one metre across (the solar panel wings extend about 14 metres) — although one able to

  13. Selected Abstracts of the 1st Congress of joint European Neonatal Societies (jENS 2015; Budapest (Hungary; September 16-20, 2015; Session “Circulation, O2 Transport and Haematology”

    Directory of Open Access Journals (Sweden)

    Various Authors

    2015-09-01

    Full Text Available Selected Abstracts of the 1st Congress of joint European Neonatal Societies (jENS 2015; Budapest (Hungary; September 16-20, 2015ORGANIZING INSTITUTIONSEuropean Society for Neonatology (ESN, European Society for Paediatric Research (ESPR, Union of European Neonatal & Perinatal Societies (UENPS, European Foundation for the Care of Newborn Infants (EFCNI, with the local host of Hungarian Society of Perinatology and Obstetric Anesthesiology, Hungarian Society of Perinatology (MPT, supported by Council of International Neonatal Nurses (COINN, organizing secretariat MCA Scientific EventsPROGRAMME COMMITTEEArtúr Beke (Hungarian Society, Morten Breindahl (ESN, Giuseppe Buonocore (UENPS, Pierre Gressens (ESPR, Silke Mader (EFCNI, Manuel Sánchez Luna (UENPS, Miklós Szabó (Hungarian Society of Perinatology, Luc Zimmermann (ESPR Session “Circulation, O2 Transport and Haematology”ABS 1. TRANSITIONAL CHANGES IN CEREBRAL BLOOD VOLUME OF TERM AND PRETERM INFANTS WITH AND WITHOUT RESPIRATORY SUPPORT AFTER BIRTH • B. Schwaberger, G. Pichler, A. Avian, C. Binder-Heschl, N. Baik, B. UrlesbergerABS 2. HEMATOLOGIC ABNORMALITIES IN THE FIRST 72 HOURS OF LIFE IN SMALL-FOR-GESTATIONAL-AGE PRETERM NEWBORNS • A. Matic, A. RistivojevicABS 3. THE ANTICOAGULANT ACTION OF ACTIVATED PROTEIN C IN VERY PRETERM INFANTS • E. Neary, N. McCallion, B. Kevane, K. Egan, M. Cotter, F. Ni AinleABS 4. SURVIVAL AFTER CARDIAC ARREST IN THE NEONATAL INTENSIVE CARE UNIT • E. Foglia, R. Langeveld, L. Heimall, A. Deveney, A. Ades, E. JensenABS 5. A PATENT DUCTUS ARTERIOSUS SEVERITY SCORE INCORPORATING MARKERS OF HAEMODYNAMIC SIGNIFICANCE AND LEFT VENTRICLE DIASTOLIC FUNCTION PREDICTS CHRONIC LUNG DISEASE • A.T. James, J.D. Corcoran, P. Dicker, O. Franklin, Y.N. Elsayed, J. Ting, A. Sehgal, A. Malikawi, A. Harabor, A.S. Soraisham, P.J. McNamaraABS 6. A STUDY TO VALIDATE THE DURATION OF ASSESSMENT OF BASELINE NIRS VALUES IN PRETERM BABIES WITH ECHOCARDIOGRAPHICALLY

  14. PREFACE: Fourth Meeting on Constrained Dynamics and Quantum Gravity

    Science.gov (United States)

    Cadoni, Mariano; Cavaglia, Marco; Nelson, Jeanette E.

    2006-04-01

    Cagliari, Italy) Roberto De Pietri (Università di Parma, Italy) Giuseppe De Risi (Università di Bari, Italy) Hans-Thomas Elze (Univ. Federal do Rio de Janeiro, Brasil) Alessandro Fabbri (Università di Bologna, Italy) Sergey Fadeev (VNIIMS, Moscow, Russia) Serena Fagnocchi (Università di Bologna, Italy) Sara Farese (Universidad de Valencia, Spain) Alessandra Feo (Università di Parma, Italy) Dario Francia (Università di Roma Tor Vergata, Italy) Francesco Fucito (Università di Roma Tor Vergata, Italy) Dmitri Fursaev (JINR, Dubna, Russia) Daniel Galehouse (University of Akron, Ohio, USA) Remo Garattini (Università di Bergamo, Italy) Florian Girelli (Perimeter Institute, Waterloo, Canada) Luca Griguolo (Università di Parma, Italy) Daniel Grumiller (Universität Leipzig, Germany) Shinichi Horata (Hayama Center of Advanced Research, Japan) Giorgio Immirzi (Università di Perugia, Italy) Roman Jackiw (MIT, Cambridge, USA) Matyas Karadi (DAMTP, University of Cambridge, UK) Mikhail Katanaev (Steklov Mathematical Institute, Moscow, Russia) Claus Kiefer (Universität Koln, Germany) John Klauder (University of Florida, Gainesville, USA) Pavel Klepac (Masaryk University, Brno, Czech Republic) Jen-Chi Lee (National Chiao-Tung University, Taiwan) Carlos Leiva (Universidad de Tarapacá, Arica, Chile) Stefano Liberati (SISSA/ISAS, Trieste, Italy) Jorma Louko (University of Nottingham, UK) Luca Lusanna (INFN, Sezione di Firenze, Italy) Roy Maartens (University of Portsmouth, UK) Fotini Markopoulou (Perimeter Institute, Waterloo, Canada) Annalisa Marzuoli (Università di Pavia, Italy) Evangelos Melas (QMW, University of London, UK) Maurizio Melis (Università di Cagliary, Italy) Vitaly Melnikov (VNIIMS, Moscow, Russia) Guillermo A. Mena Marugan (CSIC, Madrid, Spain) Pietro Menotti (Università di Pisa, Italy) Salvatore Mignemi (Università di Cagliari, Italy) Aleksandar Mikovic (Universidade Lusófona, Lisboa, Portugal) Leonardo Modesto (Université de la Mediterranée, Marseille

  15. EDITORIAL The 17th Central European Workshop on Quantum Optics

    Science.gov (United States)

    Man'ko, Margarita A.

    2011-02-01

    ), held at the University of Turku, are also available (2010 Phys. Scr. T140). The 18th Central European Workshop on Quantum Optics (CEWQO11) will be held in Madrid, Spain on 30 May--3 June 2011. It will be chaired by Professor Luis Lorenzo Sanchez Soto from the Complutense University of Madrid. List of Papers The 17th Central European Workshop on Quantum Optics in St Andrews, Scotland Ulf Leonhardt and Natalia Korolkova Double self-Kerr scheme for optical Schrödinger-cat state preparation P Adam, Z Darázs, T Kiss and M Mechler Relations between scaling transformed Husimi functions, Wigner functions and symplectic tomograms describing corresponding physical states V A Andreev, D M Davidović, L D Davidović and M D Davidović Entanglement dynamics of two independent cavity-embedded quantum dots B Bellomo, G Compagno, R Lo Franco, A Ridolfo and S Savasta Dynamical stabilization of spin systems in time-dependent magnetic fields Yu V Bezvershenko, P I Holod and A Messina Entanglement dynamics of a bipartite system in squeezed vacuum reservoirs Smail Bougouffa and Awatif Hindi On Wheeler's delayed-choice Gedankenexperiment and its laboratory realization M Božić, L Vušković, M Davidović and Á S Sanz A smooth, holographically generated ring trap for the investigation of superfluidity in ultracold atoms Graham D Bruce, James Mayoh, Giuseppe Smirne, Lara Torralbo-Campo and Donatella Cassettari Parametric amplification of the classical field in cavities with photoexcited semiconductors V V Dodonov Mutually unbiased bases: tomography of spin states and the star-product scheme S N Filippov and V I Man'ko Quantum trajectory model for photon detectors and optoelectronic devices Teppo Häyrynen, Jani Oksanen and Jukka Tulkki Entanglement in two-mode continuous variable open quantum systems Aurelian Isar A classical field comeback? The classical field viewpoint on triparticle entanglement Andrei Khrennikov Experimental investigation of the enhancement factor and the cross

  16. Selected Abstracts of the 1st Congress of joint European Neonatal Societies (jENS 2015; Budapest (Hungary; September 16-20, 2015; Session “Pulmonology”

    Directory of Open Access Journals (Sweden)

    Various Authors

    2015-09-01

    Full Text Available Selected Abstracts of the 1st Congress of joint European Neonatal Societies (jENS 2015; Budapest (Hungary; September 16-20, 2015ORGANIZING INSTITUTIONSEuropean Society for Neonatology (ESN, European Society for Paediatric Research (ESPR, Union of European Neonatal & Perinatal Societies (UENPS, European Foundation for the Care of Newborn Infants (EFCNI, with the local host of Hungarian Society of Perinatology and Obstetric Anesthesiology, Hungarian Society of Perinatology (MPT, supported by Council of International Neonatal Nurses (COINN, organizing secretariat MCA Scientific EventsPROGRAMME COMMITTEEArtúr Beke (Hungarian Society, Morten Breindahl (ESN, Giuseppe Buonocore (UENPS, Pierre Gressens (ESPR, Silke Mader (EFCNI, Manuel Sánchez Luna (UENPS, Miklós Szabó (Hungarian Society of Perinatology, Luc Zimmermann (ESPR Session “Pulmonology”ABS 1. URINE NEUTROPHIL GELATINASE-ASSOCIATED LIPOCALIN AS A MARKER OF BRONCHOPULMONARY DYSPLASIA AND RETINOPATHY OF PREMATURITY IN PRETERM NEONATES • H. Ergin, T. Atilgan, M. Dogan, O.M.A. Ozdemir, C. YeniseyABS 2. LUNG COMPLIANCE AND LUNG ULTRASOUND DURING POSTNATAL ADAPTATION IN HEALTHY NEWBORN INFANTS • L. Süvari, L. Martelius, C. Janér, A. Kaskinen, O. Pitkänen, T. Kirjavainen, O. Helve, S. AnderssonABS 3. PRE-DISCHARGE RESPIRATORY OUTCOMES IN SMALL-FOR-GESTATIONAL-AGE AND APPROPRIATE-FOR-GESTATIONAL-AGE VERY PRETERM INFANTS • A. Matic, A. RistivojevicABS 4. THE EFFECT OF CHANGING OXYGEN SATURATION TARGET RANGE ON COMPLIANCE IN OXYGEN SATURATION TARGETING IN THE NEONATAL INTENSIVE CARE UNIT • H.A. van Zanten, S. Pauws, E.C.H. Beks, B.J. Stenson, E. Lopriore, A.B. te PasABS 5. BINASAL PRONG VERSUS NASAL MASK FOR APPLYING CPAP TO PRETERM INFANTS: RANDOMIZED CONTROLLED TRIAL • B. Say, G. Kanmaz, S.S. OguzABS 6. TRAINING AND RAISING AWARENESS IMPROVES COMPLIANCE IN OXYGEN SATURATION TARGETING IN THE NEONATAL INTENSIVE CARE UNIT • H.A. van Zanten, S. Pauws, E.C.H. Beks, B.J. Stenson, E

  17. List of Participants

    Science.gov (United States)

    2008-11-01

    cole Polytechnique, Palaiseau and University of Crete Denis KleversPhysikalisches Institut, Universität Bonn Paul Koerber Max-Planck-Institut für Physik, München Simon Koers Max-Planck-Institut für Physik, München Karl KollerLudwig-Maximilians-Universität, München Peter Koroteev Institute for Theoretical and Experimental Physics (ITEP), Moscow and Max-Planck-Institut für Gravitationsphysik (AEI), Potsdam Alexey KoshelevVrije Universiteit, Brussel Costas KounnasÉcole Normale Supérieure, Paris Daniel KreflCERN, Geneva Charlotte KristjansenNiels Bohr Institute, København Finn LarsenCERN, Geneva and University of Michigan Arnaud Le DiffonÉcole Normale Supérieure, Lyon Michael LennekCentre de Physique Théorique, École Polytechnique, Palaiseau Alberto Lerda Università del Piemonte Orientale, Alessandria Andreas LiberisUniversity of Patras Maria A Lledo Universidad de Valencia Oscar Loaiza-Brito CINVESTAV, Mexico Florian Loebbert Max-Planck-Institut für Gravitationsphysik (AEI), Potsdam Yolanda Lozano University of Oviedo Dieter Luest Ludwig-Maximilians-Universität, München Tomasz Łukowski Jagiellonian University, Krakow Diego Mansi University of Crete Alberto Mariotti Università di Milano-Bicocca Raffaele Marotta Istituto Nazionale di Fisica Nucleare, Napoli Alessio Marrani Istituto Nazionale di Fisica Nucleare and LNF, Firenze Andrea Mauri University of Crete Liuba Mazzanti École Polytechnique, Palaiseau Sean McReynoldsUniversità di Milano-Bicocca AKM Moinul Haque Meaze Chittagong University Patrick Meessen Instituto de Física Teórica, Universidad Autónoma de Madrid Carlo MeneghelliUniversità di Parma and Albert-Einstein-Institut, Golm Lotta Mether University of Helsinki and CERN, Geneva René Meyer Max-Planck-Institut für Physik, München Georgios MichalogiorgakisCenter de Physique Théorique, École Polytechnique, Palaiseau Giuseppe Milanesi Eidgenössische Technische Hochschule (ETH), Zürich Samuel Monnier Université de Genève Wolfgang Mueck

  18. Selected Abstracts of the 1st Congress of joint European Neonatal Societies (jENS 2015; Budapest (Hungary; September 16-20, 2015; Session “Other”

    Directory of Open Access Journals (Sweden)

    Various Authors

    2015-09-01

    Full Text Available Selected Abstracts of the 1st Congress of joint European Neonatal Societies (jENS 2015; Budapest (Hungary; September 16-20, 2015ORGANIZING INSTITUTIONSEuropean Society for Neonatology (ESN, European Society for Paediatric Research (ESPR, Union of European Neonatal & Perinatal Societies (UENPS, European Foundation for the Care of Newborn Infants (EFCNI, with the local host of Hungarian Society of Perinatology and Obstetric Anesthesiology, Hungarian Society of Perinatology (MPT, supported by Council of International Neonatal Nurses (COINN, organizing secretariat MCA Scientific EventsPROGRAMME COMMITTEEArtúr Beke (Hungarian Society, Morten Breindahl (ESN, Giuseppe Buonocore (UENPS, Pierre Gressens (ESPR, Silke Mader (EFCNI, Manuel Sánchez Luna (UENPS, Miklós Szabó (Hungarian Society of Perinatology, Luc Zimmermann (ESPR Session “Other”ABS 1. TELEMEDICINE IN NEONATAL HOMECARE • K.G. Holm, A. Brodsgaard, G. Zachariassen, J. ClemensenABS 2. ACCEPTABILITY OF PARENT REPORT QUESTIONNAIRES FOR ROUTINE FOLLOW-UP IN LATE/MODERATELY PRETERM INFANTS • N. Armstrong, S. Johnson, E.M. BoyleABS 3. INTERNATIONAL CARE PRACTICES AROUND AN INFANT’S DEATH IN THE NICU; A SURVEY STUDY • C.M.C. van den Berg, K. Alferink, J.M. Latour, N. Valkenburg, M. van DijkABS 4. ANXIETY AND DEPRESSION OVER TIME, IN MOTHERS OF VERY PRETERM BORN CHILDREN • M. Jeukens-Visser, M. Husson, D. Meijssen, M. Flierman, P. van Schie, K. Koldewijn, A. Wassenaer-van LeemhuisABS 5. LONGITUDINAL CHANGE OF HEALTH-RELATED QUALITY OF LIFE EXPERIENCED OVER TIME BY MOTHER WITH LATE PRETERM INFANT • L.Y. Tsai, S.C. Mu, Y.L. Chen, Y.L. Guo, P.C. ChenABS 6. RELATIONSHIP BETWEEN ANXIETY LEVELS AND CLINICAL PRACTICE SKILLS AMONG STUDENTS OF PEDIATRIC NURSING LECTURE • A.S. Kurt, F.T. Arslan, S. Özkan, R. Çelen, D.A. ÇakırABS 7. ACCURACY OF SMARTPHONES FOR REVIEWING TRANSMITTED IMAGES OF NEONATAL X-RAYS • T. Vasko, M. Westberg, J.A. Dawson, L.S. Owen, M. Thio, R. Bhatia, S. Donath

  19. First Announcement and Call for Papers SECOND INTERNATIONAL SYMPOSIUM ON FLOOD DEFENCE

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    . Italy Salas, J.D. USA Dong, Zheren China Singh, R.B. India Evans, Edward UK Soroosh, Sorooshian USA Falconer, R.A. UK Takahashi,T. Japan Ikeda, Syunsuke Japan Tamai, N. Japan Jozan, Krisztina Hungary Tan, Ying China Knight, D.W. UK Todini, Ezio Italy Koch, M. Germany Toensmann, F. Germany Koffman, H.M. USA Tung, Y.K. HK Lee, Joseph.H.W. HK White, W.R. UK Onorati, Giuseppe Italy Wood, Ian New Zealand Overbeek, H.J. Netherlands van Stokkom, H. Netherland Patel, V.C. USA Yen, B.C. USA CONFERENCE STRUCTURE Keynote lectures will be given in plenary sessions. Invited lectures and papers focusing on thematic complexes will be presented in parallel sessions in the first three days (the fourth day is scheduled for a one-day city tour). Papers may also be presented in poster sessions. The conference will offer facilities, including overhead, slide and beamer (computer projector) for presentations. Submitted abstracts will be peer reviewed and papers will be invited on the basis of the abstracts. The papers themselves will also be reviewed to ensure an appropriate technical and English standard for the meeting. The proceedings of the conference will be published in book form and will be available to delegates at the time of registration. A CD of the electronic version of the proceedings will be presented to the full-registered participants. After the conference the proceedings will be widely distributed by the international book trade. A one-day city tour and two conference banquets will be arranged for the delegates and their companions,which are included in the registration fee.REGISTRATION FEE The registration fee for participation in the conference will be US $500. A discount of 10% applies for members of IAHR and the sponsor organizations (US$450) or early payment before Aug. 1, 2002. The registration fee will cover the proceedings (book and CD), publication of papers, conference banquets, city tour on the last conference day, daily lunches and coffee & tea breaks. For

  20. Selected Abstracts of the 1st Congress of joint European Neonatal Societies (jENS 2015; Budapest (Hungary; September 16-20, 2015; Session “Nutrition and gastroenterology”

    Directory of Open Access Journals (Sweden)

    Various Authors

    2015-09-01

    Full Text Available Selected Abstracts of the 1st Congress of joint European Neonatal Societies (jENS 2015; Budapest (Hungary; September 16-20, 2015ORGANIZING INSTITUTIONSEuropean Society for Neonatology (ESN, European Society for Paediatric Research (ESPR, Union of European Neonatal & Perinatal Societies (UENPS, European Foundation for the Care of Newborn Infants (EFCNI, with the local host of Hungarian Society of Perinatology and Obstetric Anesthesiology, Hungarian Society of Perinatology (MPT, supported by Council of International Neonatal Nurses (COINN, organizing secretariat MCA Scientific EventsPROGRAMME COMMITTEEArtúr Beke (Hungarian Society, Morten Breindahl (ESN, Giuseppe Buonocore (UENPS, Pierre Gressens (ESPR, Silke Mader (EFCNI, Manuel Sánchez Luna (UENPS, Miklós Szabó (Hungarian Society of Perinatology, Luc Zimmermann (ESPR Session “Nutrition and gastroenterology”ABS 1. NEONATAL ANTIBIOTICS IN PRETERM INFANTS AND RISK OF ALLERGIC DISEASES LATER IN LIFE • E. Westerbeek, A. van Zwol, L. Carstens, R. van ElburgABS 2. FRENOTOMY FOR TONGUE-TIE IN NEWBORN INFANTS: A SYSTEMATIC REVIEW • J.E. O’Shea, J.P. Foster, S.E. Jacobs, C.P.F. O’Donnell, D.A. Todd, P.G. DavisABS 3. EARLY FORMULA MAY HELP SUPPORT LONG-TERM BREASTFEEDING • Z. Stranak, J. Kolarova, M. CernaABS 4. COMPARISON OF DRY BLOOD SPOT AMINO ACID PROFILES BETWEEN PRETERM INFANTS AT TERM POSTMENSTRUAL AGE AND HEALTHY TERM NEWBORNS • C. Balcells, M. Izquierdo-Renau, M. Molero, C. Sierra, R. Artuch, I. Iglesias-PlatasABS 5. VARIABILITY IN BONE MARKERS PROFILE OF NEWBORNS AND THEIR MOTHERS AFTER DHA SUPPLEMENTATION IN PREGNANCY • L. Serrano López, M. Peña Caballero, E. Martín Álvarez, J. Diaz Castro, N. Najarabille, J.J. Ochoa, J.A. Hurtado SuazoABS 6. A SYNBIOTIC MIXTURE OF scGOS/lcFOS AND BIFIDOBACTERIUM BREVE M-16V IS ABLE TO RESTORE THE DELAYED COLONIZATION OF BIFIDOBACTERIA SPP. IN C-SECTION DELIVERED INFANTS • M.C. Chua, C. Chew, A. Goh, W.C. Chiang, R. Rao1, C. Lay, K

  1. Macromolecular crowding: chemistry and physics meet biology (Ascona, Switzerland, 10-14 June 2012)

    Science.gov (United States)

    Foffi, G.; Pastore, A.; Piazza, F.; Temussi, P. A.

    2013-08-01

    Princeton University (USA), drew attention to very important objects, namely Ribonucleoprotein (RNP) bodies. These are non-membrane-bound macromolecular assemblies that form from the dynamic interactions of RNA and proteins. The assembly of RNP bodies may sensitively depend on the biophysical features of the surrounding cytoplasm, including the degree of crowding, transport coefficients and mechanical properties. This dependency may have important implications for the RNA processing reactions involved in fundamental biological processes such as developmental cell growth. Remarkably, Brangwynne showed how RNPs behave in the cell as liquid droplets, pointing to a possible entirely new means that the cell could use to control and fine-tune its internal processes, in fact, more than that, a completely unexplored, new state of organization of living matter, and a functional one. Giuseppe Zaccai, from Institut Laue Langevin, Grenoble (France), showed that protein dynamics is more sensitive than structure to environmental factors such as crowding, solvent, temperature or pressure. Furthermore, he convincingly explained how neutron scattering provides unique experimental data to underpin MD calculations in this context. Following up on environment-induced modulations of protein functional dynamics, Ruth Nussinov, from Tel Aviv University (Israel), addressed the important problem of whether cellular signals can travel long distances in a crowded environment. She proposed a model based on the evolution of at least three properties: a modular functional organization of the cellular network, sequences in some key regions of proteins, such as linkers or loops, and compact interactions between proteins, possibly favoured by a crowded environment. The workshop ended on a keynote lecture by Jean-Marie Lehn, from the Université de Strasbourg (France). Lehn, 1987 Nobel Laureate in chemistry, offered a 'supramolecular view' of the field of molecular interactions. Supramolecular chemistry

  2. 6th International Symposium on Molecular Allergology (ISMA

    Directory of Open Access Journals (Sweden)

    Christiane Hilger

    2016-10-01

    -patient quantification of allergen-specific IgE Petra Zavadakova, Aurélie Buchwalder, Fabien Rebeaud, Iwan Märki Symposium 4: Relevance of molecular diagnostics for intervention and treatment O7 Longitudinal analysis of Bet v 1-specific epitope repertoires during birch pollen immunotherapy Barbara Gepp, Nina Lengger, Christian Möbs, Wolfgang Pfützner, Christian Radauer, Barbara Bohle O8 A natural CCD-free tool: is polistes sp. venom suitable for polybia paulista diagnosis and therapy? Karine Marafigo De Amicis, Alexandra Sayuri Watanabe, Clovis Eduardo Galvao, Daniele Danella Figo, Jose Roberto Aparecido Santos-Pinto, Mario Sergio Palma, Fabio Fernandes Morato Castro, Jorge Kalil, Fatima Ferreira, Gabriele Gadermaier, Keity Souza Santos Symposium 5: The advent of molecular allergology in epidemiology O9 Peanut oleosins: from identification to diagnostic testing Christian Schwager, Skadi Kull, Frauke Schocker, Jochen Behrends, Wolf-Meinhard Becker, Uta Jappe O10 Endotypes of oral allergy syndrome in childhood: a molecular diagnostic approach Carla Mastrorilli, Salvatore Tripodi, Carlo Caffarelli, Riccardo Asero, Arianna Dondi, Giampaolo Ricci, Carlotta Povesi Dascola, Elisabetta Calamelli, Andrea Di Rienzo Businco, Annamaria Bianchi, Tullio Frediani, Carmen Verga, Iride Dello Iacono, Diego Peroni, Giuseppe Pingitore, Roberto Bernardini, Paolo Maria Matricardi Symposium 6: Molecular AIT: which approaches will make it to market? O11 Mbc4: an innovative molecule to tackle birch pollen and concomitant food allergies Heidi Hofer, Claudia Asam, Michael Hauser, Peter Briza, Martin Himly, Christof Ebner, Fatima Ferreira O12 Challenges and solutions associated with the production of recombinant Bet v 1 allergen as a therapeutic protein Emmanuel Nony, Maxime Le Mignon, Pierrick Lemoine, Karine Jain, Kathy Abiteboul, Monica Arvidsson, Sabina Rak, Philippe Moingeon Clinical Cases: Breakthroughs and headaches from CRD: interactive session CC1 Anaphylaxis caused by lipid transfer proteins: a

  3. Selected Abstracts of the 1st Congress of joint European Neonatal Societies (jENS 2015; Budapest (Hungary; September 16-20, 2015; Session “Brain & Development”

    Directory of Open Access Journals (Sweden)

    Various Authors

    2015-09-01

    Full Text Available Selected Abstracts of the 1st Congress of joint European Neonatal Societies (jENS 2015; Budapest (Hungary; September 16-20, 2015ORGANIZING INSTITUTIONSEuropean Society for Neonatology (ESN, European Society for Paediatric Research (ESPR, Union of European Neonatal & Perinatal Societies (UENPS, European Foundation for the Care of Newborn Infants (EFCNI, with the local host of Hungarian Society of Perinatology and Obstetric Anesthesiology, Hungarian Society of Perinatology (MPT, supported by Council of International Neonatal Nurses (COINN, organizing secretariat MCA Scientific EventsPROGRAMME COMMITTEEArtúr Beke (Hungarian Society, Morten Breindahl (ESN, Giuseppe Buonocore (UENPS, Pierre Gressens (ESPR, Silke Mader (EFCNI, Manuel Sánchez Luna (UENPS, Miklós Szabó (Hungarian Society of Perinatology, Luc Zimmermann (ESPR Session “Brain & Development”ABS 1. SEPARATE EFFECTS OF LOW PATERNAL AND MATERNAL EDUCATIONAL LEVEL ON RISK OF DEVELOPMENTAL DELAY IN 4-YEAR-OLD BOYS AND GIRLS • S. de Jong, M.R. Potijk, A.E. den Heijer, S.A. Reijneveld, A.F. Bos, J.M. KerstjensABS 2. THE ASSOCIATION BETWEEN PATERNAL EDUCATIONAL LEVEL AND DEVELOPMENTAL DELAY IN PRETERM AND TERM-BORN CHILDREN AT AGE 4 • S. de Jong, J.M. Kerstjens, A.E. den Heijer, A.F. Bos, S.A. Reijneveld, M.R. PotijkABS 3. NEUROPROTECTION BY NEURONAL OVEREXPRESSION OF THE SMALL GTPase-Ras IN HYPEROXIA-INDUCED NEONATAL BRAIN INJURY • M. Serdar, K. Kempe, J. Herz, R. Herrmann, B.S. Reinboth, R. Heumann, A. Ehrkamp, U. Felderhoff-Mueser, I. BendixABS 4. REFERENCE RANGES FOR CEREBRAL TISSUE OXYGEN INDEX (cTOI IN NEONATES DURING IMMEDIATE NEONATAL TRANSITION AFTER BIRTH • N. Baik, B. Urlesberger, B. Schwaberger, G. Schmölzer, A. Avian, L. Mileder, G. PichlerABS 4. REFERENCE RANGES FOR CEREBRAL TISSUE OXYGEN INDEX (cTOI IN NEONATES DURING IMMEDIATE NEONATAL TRANSITION AFTER BIRTH • N. Baik, B. Urlesberger, B. Schwaberger, G. Schmölzer, A. Avian, L. Mileder, G. PichlerABS 6. N

  4. Macromolecular crowding: chemistry and physics meet biology (Ascona, Switzerland, 10-14 June 2012).

    Science.gov (United States)

    Foffi, G; Pastore, A; Piazza, F; Temussi, P A

    2013-08-02

    inspiring talk, Clifford Brangwynne, from Princeton University (USA), drew attention to very important objects, namely Ribonucleoprotein (RNP) bodies. These are non-membrane-bound macromolecular assemblies that form from the dynamic interactions of RNA and proteins. The assembly of RNP bodies may sensitively depend on the biophysical features of the surrounding cytoplasm, including the degree of crowding, transport coefficients and mechanical properties. This dependency may have important implications for the RNA processing reactions involved in fundamental biological processes such as developmental cell growth. Remarkably, Brangwynne showed how RNPs behave in the cell as liquid droplets, pointing to a possible entirely new means that the cell could use to control and fine-tune its internal processes, in fact, more than that, a completely unexplored, new state of organization of living matter, and a functional one. Giuseppe Zaccai, from Institut Laue Langevin, Grenoble (France), showed that protein dynamics is more sensitive than structure to environmental factors such as crowding, solvent, temperature or pressure. Furthermore, he convincingly explained how neutron scattering provides unique experimental data to underpin MD calculations in this context. Following up on environment-induced modulations of protein functional dynamics, Ruth Nussinov, from Tel Aviv University (Israel), addressed the important problem of whether cellular signals can travel long distances in a crowded environment. She proposed a model based on the evolution of at least three properties: a modular functional organization of the cellular network, sequences in some key regions of proteins, such as linkers or loops, and compact interactions between proteins, possibly favoured by a crowded environment. The workshop ended on a keynote lecture by Jean-Marie Lehn, from the Université de Strasbourg (France). Lehn, 1987 Nobel Laureate in chemistry, offered a 'supramolecular view' of the field of molecular