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Sample records for herpes canino tipo

  1. CARCINOMA COMPLEJO DE GLÁNDULA MAMARIA, ACANTOMA QUERATINIZANTE INFUNDIBULAR Y MASTOCITOMA TIPO III EN UN CANINO

    Directory of Open Access Journals (Sweden)

    Ochoa-Amaya JE

    2009-12-01

    Full Text Available Entre las neoplasias, los tumores de piel son considerados los más frecuentes en Medicina Veterinaria. El acantoma queratinizante infundibular (AQI es el tumor menos común de las neoplasias foliculares, en contraste, el mastocitoma (MC es el tumor más común de las neoplasias mesenquimales en perros, asimismo, los tumores mamarios caninos constituyen la neoplasia más frecuente en la hembra (25 a 50% de todos los tumores siendo del 41 al 50% de ellos malignos. El presente caso clínico busca documentar los hallazgos anatomopatológicos correspondientes a la presentación conjunta e infrecuente de tres neoplasias cutáneas en una perra. Se presenta el caso de un canino, hembra de 11 años de edad, cruce de raza Poodle, que fue llevada a consulta por emesis 15 días atrás y por la presencia de masas en el abdomen y en glándula mamaria. El paciente es eutanasiado. A la necropsia se hallaron masas múltiples redondeadas de variados tamaños tanto en la piel del abdómen y de glándula mamaria, así como en el parénquima del bazo e hígado. Las muestras de tejidos fueron fijadas en formalina buferada al 10% y llevadas al laboratorio para su procesamiento por técnicas histológicas rutinarias. Se diagnosticó carcinoma complejo de glándula mamaria, un MC tipo III metastásico y un AQI. Se demostró la presentación de dos neoplasias cutáneas malignas y una benigna en un mismo animal y se reportó la aparición simultánea e infrecuente del MC asociado al AQI.

  2. First detection of canine parvovirus type 2c in Brazil Detecção de parvovírus canino tipo 2c no Brasil

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    André Felipe Streck

    2009-09-01

    Full Text Available The presence of canine parvovirus type 2 (CPV-2, 2a and 2b has been described in Brazil, however, the type 2c had not been reported until now. In the current study, seven out of nine samples from dogs with diarrhea were characterized as CPV-2c, indicating that this virus is already circulating in the Brazilian canine population.No Brasil, a presença do parvovírus canino do tipo 2 (CPV-2, 2a e 2b já havia sido descrita, contudo, ainda não havia sido verificada a presença do tipo 2c. No presente trabalho, sete de nove amostras de cães com diarréia foram caracterizadas como CPV-2c, indicando que este vírus já está circulando na população canina no Brasil.

  3. Herpes

    Science.gov (United States)

    ... Links Patient Resources For Health Professionals Subscribe Search Herpes Testing Send Us Your Feedback Choose Topic At ... Content View Sources Ask Us Also Known As Herpes Culture Herpes Simplex Viral Culture HSV DNA HSV ...

  4. AISLAMIENTO DEL VIRUS HERPES BOVINO TIPO 1 EN BOVINOS DEL DEPARTAMENTO DE CÓRDOBA - COLOMBIA

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    Victor Vera A

    2008-12-01

    Full Text Available Objetivo. Realizar el aislamiento del virus herpes bovino tipo 1 (BHV-1 en ganado bovino con antecedentes de infertilidad. Materiales y métodos. A partir de 85 animales, provenientes de diferentes áreas rurales del departamento de Córdoba, Colombia, sin antecedentes de vacunación y con titulos neutralizantes contra la enfermedad de la rinotraqueitis bovina infecciosa (IBR por seroneutralización, se escogieron dos toros y una vaca para hacer aislamiento de HVB-1. Los animales fueron inmunosuprimidos con Dexametasona, y se obtuvieron muestras con hisopos nasales, oculares y de lavado prepucial en los toros y vaginales en la vaca respectivamente. Resultados. Se observó un efecto citopático a las 3 horas después de la inoculación de las células MDBK con el lavado genital de la vaca y a las 24 horas en los toros, con exposición del efecto en “racimo” a las 48 horas. El aislamiento en ambos tipos de muestras, sugiere que la reactivación viral fue seguida por una fase de viremia y excreción del virus en las secreciones naturales. Conclusiones. El aislamiento del virus HVB-1 en los reproductores aparentemente sanos pero con títulos a la prueba de seroneutralización, establece la presencia de latencia viral en éstos animales, importante factor epidemiológico en la difusión de la enfermedad a nivel de campo. Se deben iniciar los estudios necesarios para establecer el subtipo de virus actuante en el campo, para conocer sus características antigénicas y su correspondencia con las cepas vacunales.

  5. Relaciòón entre el herpes simple tipo 2 y las lesiones preinvasivas de cuello uterino

    OpenAIRE

    Carrero, Yenddy; Facultad Experimental de Ciencias, Universidad del Zulia. Zulia, Venezuela.; Callejas, Diana; Instituto de Investigaciones Clínicas, Facultad de Medicina, Universidad del Zulia. Zulia, Venezuela.; Estévez, Jesús; Instituto de Investigaciones Clínicas, Facultad de Medicina, Universidad del Zulia. Zulia, Venezuela.; Gotera, Jennifer; Facultad Experimental de Ciencias, Universidad del Zulia. Zulia, Venezuela.; Núñez, José; Departamento de Ginecología y Obstetricia, Hospital “Manuel Noriega Trigo”, Instituto Venezolano de los Seguros Sociales. Zulia, Venezuela.; Atencio, Ricardo; Laboratorio Regional de Referencia Virológica, Facultad de Medicina, Universidad del Zulia. Zulia, Venezuela.; Porto, Leticia; Laboratorio Regional de Referencia Virológica, Facultad de Medicina, Universidad del Zulia. Zulia, Venezuela.; Monsalve, Francisca; Cátedra de Virología, Escuela de Bioanálisis, Facultad de Medicina, Universidad del Zulia. Zulia, Venezuela.

    2006-01-01

    Objetivos: Determinar la presencia y relación del virus herpes simple tipo 2 (VHS-2) en mujeres con diferentes gra - dos de lesiones preinvasivas de cuello uterino. Materiales y métodos: Se estudiaron 176 mujeres con lesiones preinvasivas de cuello uterino y 40 mujeres como grupo control con cuello uterino sano, que asistieron a la consulta ginecológica en diferentes centros de salud, durante los años 2002-2005 en Maracaibo-Venezuela. A las pacientes se les tomó un hisopado del exocervix y un...

  6. Relación entre el herpes simple tipo 2 y las lesiones preinvasivas de cuello uterino

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    Yenddy Carrero

    2006-10-01

    Full Text Available Objetivos: Determinar la presencia y relación del virus herpes simple tipo 2 (VHS-2 en mujeres con diferentes grados de lesiones preinvasivas de cuello uterino. Materiales y métodos: Se estudiaron 176 mujeres con lesiones preinvasivas de cuello uterino y 40 mujeres como grupo control con cuello uterino sano, que asistieron a la consulta ginecológica en diferentes centros de salud, durante los años 2002-2005 en Maracaibo-Venezuela. A las pacientes se les tomó un hisopado del exocervix y una biopsia dirigida del sitio de la lesión por colposcopía. La determinación de VHS-2 se realizó a través de inmunofluorescencia directa. Resultados: La presencia de infección por VHS-2 fue 44 /176 (25%. El mayor número de VHS-2 se obtuvo en las pacientes con grado de lesión tipo NIC II (66,7%. El mayor porcentaje de infección por VHS-2 se determinó en las pacientes que iniciaron sus relaciones sexuales entre los 15 y 20 años (34,5%, las relaciones sexuales diarias (50%, así como relaciones de tipo orogenital fueron consideradas las conductas de mayor riesgo para adquirir la infección. Conclusiones: No se evidenció una relación directa entre VHS-2 y la presencia de cáncer. Los factores de riesgo asociados con la infección son similares a otras ITS, y están ligados con la conducta sexual y hábitos propios del individuo.

  7. A phylogenetic study of canine parvovirus type 2c in midwestern Brazil Estudo filogenético do parvovírus canino tipo 2c no Centro-Oeste do Brasil

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    Danúbia S. Fontana

    2013-02-01

    Full Text Available Since the late 1970s, canine parvovirus type 2 (CPV-2 has emerged as a causative agent of fatal severe acute hemorrhagic enteritis in dogs. To date, three antigenic types of CPV-2 were described worldwide (CPV-2a/b/c. This study was conducted to determine the variants of CPV-2 circulating in dogs from the Cuiabá Municipality in Midwestern Brazil. Out of 50 fecal samples, collected between 2009 and 2011, 27 tested positive for CPV-2. A 583 bp fragment of the VP2 gene was amplified by PCR, 13 representative samples were analyzed further by DNA sequencing. All strains were characterized as CPV-2c, displayed a low genetic variability although observed several amino acid substitution. These findings indicated that CPV-2c has been circulating in dogs from the Cuiabá Municipality in Midwestern Brazil.Desde o final dos anos de 1970, o parvovírus canino tipo 2 (CPV-2 tem emergido como agente de severa e fatal enterite hemorrágica, principalmente em cães com idade inferior a seis meses. Três variantes antigênicas de CPV-2 foram descritas mundialmente (CPV-2a/b/c. O objetivo do estudo foi determinar a presença do CPV-2 e suas variantes circulantes em cães no Município de Cuiabá, Centro-oeste, Brasil. Das 50 amostras fecais, coletadas entre 2009 e 2011, 27 foram positivas para CPV-2 na PCR, sendo 13 analisadas pelo sequenciamento de um fragmento de 583 pares de base do gene VP2. Todas as cepas foram caracterizadas como CPV-2c e apresentaram baixa variabilidade genética. Estes achados indicaram que o CPV-2c está circulando na população canina do Município de Cuiabá, Região Centro-Oeste do Brasil.

  8. Herpes and its hearing implications: a literature review/ Do herpes e suas implicacoes audiologicas: uma revisao de literatura

    National Research Council Canada - National Science Library

    Schuster, Larissa Cristina; Buss, Ceres

    2009-01-01

    Tema: herpes e audiologia. Objetivo: realizar revisao teorica principalmente sobre os virus herpes simples tipo 1, herpes simples tipo 2 e varicela-zoster, bem como sobre seus efeitos na audicao humana...

  9. Seroprevalencia de la infección por el virus herpes simplex tipo 2 en tres grupos poblacionales de la Ciudad de México Herpes simplex virus type 2 seroprevalence among three female population groups from Mexico City

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    Carlos J Conde-González

    2003-01-01

    Full Text Available OBJETIVO: Determinar la seroprevalencia de infección por el virus herpes simplex tipo 2 y los factores epidemiológicos asociados a ella, en tres grupos de población femenina de la Ciudad de México. MATERIAL Y MÉTODOS: Estudio transversal efectuado en el año 2000, que incluyó mujeres de la Ciudad de México diagnosticadas con cáncer de mama, cáncer cervical , y mujeres de población general negativas al Papanicolaou. Todas las participantes proporcionaron su consentimiento informado para responder un cuestionario sociodemográfico y de vida sexual, y permitir la toma de una muestra sanguínea. La presencia de anticuerpos contra el virus herpes simplex tipo 2 entre las mujeres se realizó por la técnica de "Western blot"específica para el virus herpes simplex tipo 2; las asociaciones entre estos resultados y los datos de la encuesta se analizaron estadísticamente, de manera cruda y ajustada. RESULTADOS: Las mujeres concáncer cervical tuvieron una seroprevalencia de infección por el virus herpes simplex tipo 2 de 46.8% (191/408; las de población general negativas al Papanicolaou de 29.3% (214/730, y aquellas con cáncer de mama de 22.6% (29/128. Las variables asociadas significativamente a la seropositividad contra este virus fueron la edad creciente, el aumento en el número de parejas sexuales, tener cáncer cervical, y entre las mujeres con esa patología, el inicio antes de los 21 años de edad de la actividad sexual y el estar divorciadas o separadas. CONCLUSIONES: Los hallazgos observados revelaron diferencias estadísticas en la seroprevalencia del virus herpes, de acuerdo con los grupos poblacionales estudiados. La frecuencia global de la infección viral entre las participantes las sitúa en un riesgo intermedio, en comparación con otros grupos poblacionales que en México son de alto y bajo riesgo (trabajadoras sexuales y estudiantes universitarias, respectivamente, analizados en años recientes. Las principales caracter

  10. Anatomia interna dos caninos inferiores

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    Oliveira, Simone H.G; Iorio, Lecy S.

    2010-01-01

    A falta de conhecimento da anatomia da cavidade pulpar é uma das principais razões do insucesso da terapia endodôntica dos caninos inferiores. Foram utilizados 1040 caninos inferiores cuja incidência de bifurcações foi avaliada através de estudo radiográfico e comparada com o método de injeção e diafanização dos mesmos dentes. Também foram estudadas outras características internas visualizad...

  11. Linfoma de Células del Manto en un Canino: Reporte de Caso

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    Puicón N., Víctor; Laboratorio de Histología, Embriología y Patología Veterinaria, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima, Perú; Sandoval C., Nieves; Laboratorio de Histología, Embriología y Patología Veterinaria, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima, Perú; Díaz C., Diego; Clínica de Animales Menores, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima, Perú; Aguilar, Vladimir; Clínica de Animales Menores, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima, Perú; Tabacchi N., Luis; Laboratorio de Histología, Embriología y Patología Veterinaria, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima, Perú; Cahua U., Jacqueline; Clínica de Animales Menores, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima, Perú

    2014-01-01

    Se describe el caso de un canino Staffordshire Terrier macho, de 11 años, con linfoma esplénico de tipo células del manto, proceso neoplásico hematopoyético de presentación rara. A case of splenic mantle cell hematopoietic neoplasia in a male Staffordshire Terrier dog, 11 years old, is described.

  12. Genetic diversity of the VP1/VP2 gene of canine parvovirus type 2b amplified from clinical specimens in Brazil Diversidade genética no gene VP1/VP2 do parvovirus canino tipo 2b amplificado de material clínico no Brasil

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    Cesar A. D. Pereira

    2000-10-01

    Full Text Available We evaluated the genetic diversity in the VP1/VP2 gene of CPV type 2b isolates from symptomatic dogs in Brazil. A total of 21 isolates collected from 1990 through 1995 previously typed as CPV2b by PCR assay were studied. Overall we found a high degree of similarity among sequences from different CPV clinical isolates collected. Genetic analysis of this selected region gave no indication of a specific Brazilian parvovirus lineage.Neste estudo foi avaliada a diversidade genética no gene VP1/VP2 do parvovírus canino tipo 2b a partir de amostras isoladas de cães sintomáticos no Brasil. Foram estudadas 21 amostras coletadas no período de 1990 à 1995, previamente caracterizadas como CPV 2b pela técnica de PCR. Observou-se alto grau de similaridade entre as seqüências estudadas e a análise genética da região selecionada não indicou a presença de uma linhagem brasileira específica.

  13. Isolation and characterization of canine parvovirus type 2c circulating in Uruguay Isolamento e caracterização da cepa tipo 2c do parvovirus canino circulante no Uruguai

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    Andrea Blanc Pintos

    2011-08-01

    Full Text Available This research reports the first CPV-2c isolation in cell culture (canine fibroma cell line A-72 in Uruguay. The isolates were obtained from 13 rectal swabs of Uruguayan dogs with parvovirosis. Samples were submitted to PCR with two sets of primers, restriction fragment length polymorphism (RFLP, partial sequencing of the gene encoding for VP2 capsid protein and phylogenetic characterization. The strain isolated was confirmed as CPV-2c. These results contribute to a better knowledge of CPV strains circulating in Uruguay and promote an evaluation of the efficacy of heterologous vaccines used to protect against the circulating strains.Este trabalho relata o primeiro isolamento do CPV-2c em cultura de células (linhagem celular de fibroma canino A-72, no Uruguai. Os isolados foram obtidos a partir de 13 suabes retais de cães uruguaios com parvovirose. As amostras foram submetidas à reação em cadeia da polimerase (PCR com dois pares de primers, polimorfismo de comprimento de fragmentos de restrição (RFLP, sequenciamento parcial do gene que codifica a proteína capsidial VP2 e caracterização filogenética. A cepa isolada foi confirmada como CPV-2c. Os resultados contribuem para um melhor conhecimento das cepas do CPV circulantes no Uruguai e incitam uma maior investigação sobre a eficácia das vacinas produzidas com cepas heterólogas utilizadas atualmente para proteger contra cepas circulantes.

  14. Avaliação da Soroprevalência dos Vírus Herpes Simples Tipos 1 e 2 em Parturientes Seroprevalence Evaluation of Herpes Simplex Virus 1 and 2 Among Pregnant Women

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    Marina Carvalho Paschoini

    2001-02-01

    Full Text Available Objetivos: avaliar a soroprevalência da infecção causada pelo HSV-2 entre as parturientes do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto (HCFMRP-USP e padronizar técnicas laboratoriais para atender a este propósito. Métodos: foram avaliadas 1.500 amostras de sangue de parturientes atendidas no Centro Obstétrico do Departamento de Ginecologia e Obstetrícia do HCFMRP-USP, entre 1º de janeiro e 31 de outubro de 1996. Para determinar a real prevalência da infecção por HSV-2 foi padronizada a técnica de ELISA, verificando-se que esta não apresentava especificidade suficiente para discriminar os dois tipos virais (75%, delineando a necessidade de utilizar-se técnica de maior poder discriminatório. A técnica padronizada para esta finalidade foi o Western blot, capaz de detectar a proteína viral específica do HSV-2. Resultados: a soroprevalência para infecção herpética, pelos dois tipos virais (HSV-1 e HSV-2, foi de 94,5%, utilizando a técnica de ELISA. Com o emprego da técnica de Western blot, encontrou-se a soroprevalência de 31,9% pelo HSV-2 na população avaliada, quer sintomática ou assintomática. Conclusão: verifica-se elevada prevalência do estado de portadora da infecção pelos HSV, evidenciada pelo alto índice de positividade para os anticorpos contra estes vírus. O teste ELISA não mostrou especificidade suficiente para discriminar os anticorpos anti-HSV-2 dos anti-HSV-1.Purpose: to evaluate the seroprevalence of infection caused by HSV-2 among pregnant women delivering at the University Hospital, Faculty of Medicine of Ribeirão Preto (UHFMRP-USP and to standardize laboratory techniques to be used for this purpose. Methods: a total of 1500 blood samples from pregnant women seen at the Obstetric Center of the Department of Gynecology and Obstetrics, UHFMRP-USP, between January 1st and October 31st, 1996, were evaluated. To determine the real prevalence of HSV-2 infection, the ELISA

  15. Herpes - resources

    Science.gov (United States)

    Genital herpes - resources; Resources - genital herpes ... following organizations are good resources for information on genital herpes : March of Dimes -- www.marchofdimes.com/pregnancy/complications- ...

  16. La gD2 coadministrada con el AFCo1 por vía intranasal induce inmunidad protectora contra virus de herpes simple tipo 2 en ratones

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    Osmir Cabrera

    2012-12-01

    Full Text Available La infección por virus herpes simple tipo 2 (VHS-2 continúa siendo un problema de salud mundial. Esta infección es transmitida sexualmente y es la principal causa de úlceras genitales. La prevención de esta enfermedad requiere de la utilización de vacunas mucosales, pues las vacunas parenterales no han sido exitosas. Por otra parte, no existen adyuvantes mucosales, por lo que el desarrollo de estos es esencial para la estrategia de estas vacunas. La administración intranasal (IN de la glicoproteína D del VHS-2 (gD2, coadministrada con el cocleato (AFCo1+gD2 sería igualmente efectiva con la gD2 incluida (AFCo1-gD2. Se inocularon ratones hembras C57BL/6 por la vía IN con gD2, contenida dentro del cocleato, coadministrada con el cocleato o gD2 sola. Se determinaron los niveles de IgG anti gD2 en suero y lavado vaginal, así como las subclases de IgG anti gD2 por ELISA. Se determinó la respuesta linfoproliferativa en células de bazo, el perfil de citoquinas Th1/Th2, los signos de la enfermedad y la protección frente al reto viral. Se observaron altos títulos de IgG e IgG2c anti gD2 en el suero de los animales inoculados con la gD2 y el AFCo1 como adyuvante. No se observaron diferencias significativas (p>0,05 entre los grupos que recibieron AFCo1+gD2 y los que recibieron AFCo1-gD2. Se observó un perfil de citoquinas tipo Th1 y un 100% de sobrevida en los grupos que recibieron el AFCo1 como adyuvante de la gD2, mientras que en el grupo que recibió la gD2 sola no se observó protección. Estos resultados indican que la gD2 puede ser utilizada coadministrada con AFCo1 por vía IN como un potencial candidato vacunal contra VHS-2.

  17. Oral Herpes

    Science.gov (United States)

    ... Dry Mouth Burning Mouth Tooth Decay See All Oral Complications of Systemic Diseases Cancer Treatment Developmental Disabilities ... care. NIDCR > Image Gallery > Oral Health > Oral Herpes Oral Herpes Main Content Title: Oral Herpes Description: Herpes ( ...

  18. Herpes Simplex

    Science.gov (United States)

    ... skin diseases Athlete's foot Chickenpox Cold sores Genital herpes Genital warts Head lice Herpes simplex Impetigo Molluscum contagiosum ... swollen lymph nodes (glands) in the neck (oral herpes) or groin (genital herpes) are possible. Problems urinating . People (most often ...

  19. Herpes Keratitis

    Science.gov (United States)

    ... Stories Español Eye Health / Eye Health A-Z Herpes Keratitis Sections What is Herpes Keratitis? Herpes Keratitis ... Herpes Keratitis Symptoms Herpes Keratitis Treatment What is Herpes Keratitis? Leer en Español: ¿Qué es la queratitis ...

  20. Primoinfección por virus del herpes simp le tipo 1. Manejo farmacológico y caracteristicas clínicas

    OpenAIRE

    Hernan Francisco Sariego Santana; Antonio José Díaz Caballero; Rosa Mercedes Baldiris Ávila

    2013-01-01

    ResumenEl presente artículo reporta un caso clínico de gingivoestomatitis herpética primaria y una breve revisión de los medicamentos usados para tratar la infección por virus del herpes simple (HSV). Se presenta un paciente con múltiples ulceraciones confluentes tanto en la cara ventral como en la dorsal de la lengua y en los labios, compatible con gingivoestomatitis herpética primaria. Esta forma de presentarse las ulceraciones y la edad del paciente son frecuentes en pacientes VIH positivo...

  1. Carcinoma hepatocelular canino: Reporte de un caso

    OpenAIRE

    Edwin Buriticá G; Ximena Barbosa S; Diego Echeverry B

    2009-01-01

    Objetivo Presentar el caso de un paciente canino, con enfermedad hepática, asociada a carcinoma hepatocelular. Materiales y métodos Fue estudiado el caso de un paciente canino de raza Pitt bull de 10 años de edad, al que se le encontraron múltiples nódulos distribuidos en todo el parénquima hepático, con diagnostico histopatológico de carcinoma hepatocelular. Resultados Se expone el caso clínico de un paciente canino de raza Pitt bull, que es presentado a consulta externa por presentar de...

  2. Genital Herpes

    Science.gov (United States)

    Genital herpes is a sexually transmitted disease (STD) caused by a herpes simplex virus (HSV). It can cause sores on ... also infect their babies during childbirth. Symptoms of herpes are called outbreaks. You usually get sores near ...

  3. Primoinfección por virus del herpes simp le tipo 1. Manejo farmacológico y caracteristicas clínicas

    Directory of Open Access Journals (Sweden)

    Hernan Francisco Sariego Santana

    2013-10-01

    Full Text Available ResumenEl presente artículo reporta un caso clínico de gingivoestomatitis herpética primaria y una breve revisión de los medicamentos usados para tratar la infección por virus del herpes simple (HSV. Se presenta un paciente con múltiples ulceraciones confluentes tanto en la cara ventral como en la dorsal de la lengua y en los labios, compatible con gingivoestomatitis herpética primaria. Esta forma de presentarse las ulceraciones y la edad del paciente son frecuentes en pacientes VIH positivo (Virus de la inmunodeficiencia humana, esto no pudo ser comprobado en el caso ya que el paciente dejo de asistir a consulta luego de recibido el tratamiento. El tratamiento instaurado fue aciclovir tabletas 200 mg cada 6 horas vía oral por 10 días. Cabe mencionar que los tratamientos para el virus del herpes simple con aciclovir no están aprobados por la Administración de Alimentos y Drogas de los Estados Unidos (FDA siglas en inglés pero si son aceptados por el Centro de Control de Enfermedades (CDC siglas en ingles, también se utilizó gel de polivinilpirrolidona, hialuronato de sodio para facilitar la deglución del paciente. (DUAZARY 2011 No. 2, 199 - 205AbstractThis article reports a case of primary herpetic gingivostomatitis and a brief review of drugs used to treat infection with herpes simplex virus (HSV. We present a patient with multiple confluent ulcers in both the ventral and the dorsal tongue and lips, compatible with primary herpetic gingivostomatitis. This way of presenting ulceration and patient age are common in HIV positive patients (human immunodeficiency virus, this could not be found in the case because the patient stopped coming to see after the treatment. Acyclovir treatment was introduced 200 mg tablets orally every 6 hours for 10 days. It is noteworthy that the treatments for herpes simplex virus with acyclovir are not approved by the Food and Drug Administration (FDA but if accepted by the Center for Disease Control

  4. Hidronefrosis en un canino de 3 meses. Reporte de un caso clínico

    OpenAIRE

    Tatiana Useche| ;; Paola Fernandez|; Fernando A. Cala:; Giovanny Vargas; Victor H Arcila Q| Vilma Castellanos|

    2006-01-01

    Las patologías a nivel abdominal y en particular las de tipo renal con frecuencia generan cuadros clínicos complejos que dificultan su interpretación aun considerando el apoyo en herramientas diagnósticas. La valoración en animales jóvenes debe considerar la correlación con patologías de tipo congénito (defectos del desarrollo). Un Canino macho de nombre Kasuki, de 3 meses de edad, raza criollo, es llevado al Centro Medico Quirúrgico Veterinario de la Universidad Cooperativa de Colombia (CMQV...

  5. Caracterización molecular de un aislamiento cubano de parvovirus canino

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    Anniet Fresneda-Disotuar

    2015-12-01

    Full Text Available El parvovirus canino tipo 2 (VPC-2 es el agente causal de una enfermedad infecto-contagiosa que produce gastroenteritis aguda hemorrágica que afecta a caninos jóvenes. El VPC-2 es un virus con genoma ADN, pequeño, desnudo y muy resistente a las condiciones ambientales que emergió y se expandió rápidamente a fines de la década de los años 70. En los años 80 surgieron consecutivamente dos variantes antigénicas, denominadas VPC-2a y VPC-2b. En el 2000 se detectó una nueva variante antigénica llamada VPC-2c, reportándose con frecuencia en comunidades caninas de varios países del mundo. El objetivo de este trabajo consistió en caracterizar un aislamiento cubano de parvovirus canino, atenuado y adaptado a cultivo celular. El material genético fue amplificado por reacción en cadena de la polimerasa y secuenciado posteriormente. Las secuencias obtenidas fueron analizadas y comparadas con secuencias de aislados y cepas conocidas depositadas en las bases de datos, donde se evidenció que el aislamiento cubano era del tipo VPC-2.

  6. Ocorrência de neoplasias em caninos na cidade de Salvador, Bahia (Achados de biopsias.

    Directory of Open Access Journals (Sweden)

    V. T. F. de Souza

    2005-03-01

    Full Text Available RESUMO: Estudaram-se microscopicamente 138 amostras obtidas de biopsias de diversos tecidos e órgãos de caninos da região metropolitana de Salvador, Bahia. Foram diagnosticadas 126 casos de neoplasias de vários tipos histológicos, sobressaindo os tumores de pele e os da glândula mamária . PALAVRAS CHAVE: Neoplasias, caninos, tumores, patologia , achados de biopsia , câncer, neoplasmas SUMMARY: Microscopic examinations were performed in the 138 biopsies of various tecides and organs of the canines from the metropolitan regions of Salvador, Bahia. Diagnostic showed 126 cases of the neoplasms of various histologic appearances, must of the teguments and mammary glands tumors. KEYWORDS: Neoplasies, canines, tumours, pathology, biopsies, findings, cancer, neoplasms.

  7. Pregnancy Complications: Genital Herpes

    Science.gov (United States)

    ... percent) women in the United States has genital herpes. Can genital herpes cause complications during pregnancy? Yes. Genital herpes ... sex Having your period Stress How does genital herpes spread? Genital herpes is caused by two viruses called herpes ...

  8. Pregnancy and herpes

    Science.gov (United States)

    HSV; Congenital herpes; Herpes - congenital; Birth-acquired herpes; Herpes during pregnancy ... Newborn infants can become infected with herpes virus: In the uterus (this is ... herpes, the most common method of infection) Right ...

  9. Gingivoestomatitis herpética

    OpenAIRE

    Gruce, M.; Lajara Lambrecht, M.; Bonavita, A.

    2015-01-01

    Introducción: La gingivoestomatitis herpética primaria (GEHP) es la primo infección causada por el virus herpes simple tipo 1 (VHS-1); si bien la infección inicial suele ser subclínica, alrededor del 1% de los pacientes experimenta manifestaciones agudas en forma de GEHP. Las manifestaciones clínicas son malestar general, odinofagia, fiebre, linfoadenopatías y lesiones bucales. Descripción del caso: Se diagnostica un caso clínico de primo infección herpética primaria en un pre adolescente de ...

  10. Factores asociados con la seropositividad a Brucella canis en criaderos caninos de dos regiones de Antioquia, Colombia

    Directory of Open Access Journals (Sweden)

    Laura Castrillón-Salazar

    2013-10-01

    Full Text Available El objetivo fue determinar la seroprevalencia a Brucella canis en perros y humanos convivientes en criaderos caninos y explorar los factores de riesgo asociados a la seropositividad. Se tomaron 20 criaderos, en los cuales se realizó diagnóstico serológico por PARP-2ME de 428 caninos y 91 humanos. Se aplicó una encuesta para determinar los factores de riesgo y se analizaron los datos mediante regresión logística. Se determinó una seroprevalencia de 15% en caninos y 9% en humanos convivientes. Se determinaron como factores asociados a la seropositividad canina el historial de seropositividad canina, conservar los caninos seropositivos, historial de aborto, higiene y protección del operario deficientes durante el servicio reproductivo, y procedimiento inseguro durante la atención de abortos. Como factores protectores se establecieron la ubicación rural de los criaderos, facilidad de aseo de los caniles, PARP-2ME premonta, y procedimiento seguro durante la atención de partos. En humanos se determinaron factores asociados: criaderos ubicados en el Valle Aburrá y de tipo urbano.

  11. CARCINOMA HEPATOCELULAR CANINO: REPORTE DE UN CASO

    Directory of Open Access Journals (Sweden)

    Edwin Buriticá G

    2009-08-01

    Full Text Available Objetivo Presentar el caso de un paciente canino, con enfermedad hepática, asociada a carcinoma hepatocelular. Materiales y métodos Fue estudiado el caso de un paciente canino de raza Pitt bull de 10 años de edad, al que se le encontraron múltiples nódulos distribuidos en todo el parénquima hepático, con diagnostico histopatológico de carcinoma hepatocelular. Resultados Se expone el caso clínico de un paciente canino de raza Pitt bull, que es presentado a consulta externa por presentar decaimiento y distensión abdominal, una vez realizado el examen físico sistemático se evidenció hepatomegalia y un crecimiento anormal hacia la región del mesogastrio derecho. Los exámenes paraclinicos e histopatológicos demostraron la presencia de enfermedad hepática asociada a carcinoma hepatocelular. Conclusiones El carcinoma hepatocelular es una entidad de rara presentación, clínicamente cursa con signos muy similares a otras alteraciones tumorales de compromiso hepático, su diagnostico suele ser histopatológico.

  12. Genital herpes.

    OpenAIRE

    1980-01-01

    Genital herpes is an infection with herpes simplex virus type 1 (HSV-1) or type 2 (HSV-2). The typical clinical features include painful shallow anogenital ulceration. It is among the most common sexually transmitted diseases, with up to 23% of adults in the UK and US having antibodies to HSV-2.

  13. Herpes Zoster.

    Science.gov (United States)

    Schmader, Kenneth

    2016-08-01

    Herpes zoster causes significant suffering owing to acute and chronic pain or postherpetic neuralgia (PHN). Varicella-zoster virus-induced neuronal destruction and inflammation causes the principal problems of pain, interference with activities of daily living, and reduced quality of life in older adults. The optimal treatment of herpes zoster requires early antiviral therapy and careful pain management. For patients who have PHN, evidence-based pharmacotherapy using topical lidocaine patch, gabapentin, pregabalin, tricyclic antidepressants, or opiates can reduce pain burden. The live attenuated zoster vaccine is effective in reducing pain burden and preventing herpes zoster and PHN in older adults. Copyright © 2016 Elsevier Inc. All rights reserved.

  14. Serum herpes simplex antibodies

    Science.gov (United States)

    ... causes cold sores (oral herpes). HSV-2 causes genital herpes. How the Test is Performed A blood sample ... person has ever been infected with oral or genital herpes . It looks for antibodies to herpes simplex virus ...

  15. Hipoadrenocorticismo primario canino: reporte de caso

    OpenAIRE

    Granados, J. L.; Martínez, L. M.; Galindo, V.

    2011-01-01

    Un canino macho Cocker Spaniel de 6 meses de edad fue presentado a la Clínica para Pequeños Animales de la Universidad Nacional de Colombia, con historia de vómito y diarrea de una semana de duración. El paciente presentaba hiperkalemia, y los electrocardiogramas realizados fueron compatibles con este hallazgo. El diagnóstico de hipoadrenocorticismo primario fue confirmado mediante la realización de una prueba de estimulación con ACTH. Posteriormente a la muerte súbita del paciente, el examen...

  16. Análise da reativação do vírus herpes simples tipo 1 após procedimentos odontológicos pela técnica da reação em cadeia da polimerase

    OpenAIRE

    Luciano Marques da Silva

    2006-01-01

    O vírus do herpes simples tipo 1 (HSV-1) é um vírus de DNA e um membro da família do herpesvírus humano (HHV). Em geral, mais de 90% da população apresentam anticorpos contra o HSV-1, sendo que 40% dessas pessoas têm susceptibilidade em desenvolver manifestações herpéticas secundárias. A reativação do HSV-1 na mucosa bucal pode ser induzida por vários fatores como stress, luz solar, menstruação e trauma físico. O objetivo do presente estudo foi avaliar o impacto de procedimentos cirúrgicos od...

  17. Genital Herpes

    Science.gov (United States)

    ... after an outbreak. Using male latex condoms (or polyurethane for those allergic to latex) may reduce your ... with an HIV-infected partner. Taking suppressive therapy does not decrease this risk. How can the herpes ...

  18. Herpes zoster

    Science.gov (United States)

    Schmader, Kenneth

    2016-01-01

    Synopsis Herpes zoster afflicts millions of older adults annually worldwide and causes significant suffering due to acute and chronic pain, or postherpetic neuralgia (PHN). Herpes zoster is caused by the reactivation of varicella-zoster virus (VZV) in sensory ganglia in the setting of age, disease and drug-related decline in cellular immunity to VZV. VZV-induced neuronal destruction and inflammation causes the principal problems of pain, interference with activities of daily living and reduced quality of life in older adults. To address these problems, the optimal treatment of herpes zoster requires early antiviral therapy and careful pain management. For patients who develop PHN, evidence-based pharmacotherapy using topical lidocaine patch, gabapentin, pregabalin, tricyclic antidepressants, and/or opiates can reduce pain burden. The live attenuated zoster vaccine is effective in reducing pain burden and preventing herpes zoster and PHN in older adults. PMID:17631237

  19. Enfermedad renal poliquistica asociada a linfoma extranodal en un canino

    OpenAIRE

    Echeverry, Diego; Barbosa, Ximena; Buriticá, Edwin

    2006-01-01

    Objetivo: Presentar el caso de un paciente canino, con enfermedad renal poliquística, asociada a linfoma extranodal. Materiales y métodos: Se estudió el caso de un paciente canino de raza Siberian Husky de 7 años de edad, al que se le encontraron múltiples nódulos renales bilaterales, con diagnóstico histopatológico de linfoma extranodal. Resultados: Se expone el caso clínico de un paciente canino de raza Siberian Husky, que es presentado a consulta dermatológica por exhibir lesiones alopécic...

  20. Influencia de las vías de inmunización mucosales sobre la protección contra herpes simple tipo 2 con el AFCo1 como adyuvante

    Directory of Open Access Journals (Sweden)

    Osmir Cabrera1

    2011-12-01

    Full Text Available Las vacunas mucosales se han planteado como una estrategia prometedora para inducir protección mucosal. El virus herpes simple tipo 2 es uno de los patógenos más frecuentes en el humano transmitidos por vía sexual. Varios candidatos vacunales contra este patógeno se han evaluado, pero no han sido efectivos, por lo que aún no se cuenta con una vacuna profiláctica ni terapéutica. La gD2 es una glicoproteína recombinante y está reportada como uno de los antígenos de importancia vacunal contra este germen. Contamos con el cocleato derivado del proteoliposoma de Neisseria meningitidis serogrupo B (AFCo1 que ha mostrado capacidades adyuvantes por varias vías de inmunización. El objetivo de este trabajo fue evaluar la protección inducida en ratones por el AFCo1-gD2, administrada por diferentes vías mucosales. Se utilizaron ratones hembras C57BL6, los cuales fueron inmunizados por vía intranasal (IN, intravaginal (IVag o intrarrectal (IR con AFCo1-gD2 o gD2 sola. Se determinó la IgG anti gD2, la proliferación celular específica, la replicación viral en lavado vaginal, los signos de la enfermedad y la protección frente al reto viral. Se obtuvo respuestas significativas de IgG anti gD2 por todas las vías, aunque la IN mostró los valores más elevados. Se observó proliferación celular en células de animales inmunizados IN e IVag, pero no por vía IR. Se observó la mayor protección (100% en los animales inmunizados por vía IN. Se concluye que la vía nasal es la más prometedora en la inducción de protección contra este reto viral.

  1. Inseminación artificial con semen fresco, refrigerado y congelado : Aplicación y desarrollo en caninos

    OpenAIRE

    Stornelli, María Alejandra; Stornelli, María Cecilia; Arauz, María Sandra; Sota, Rodolfo Luzbel de la

    2001-01-01

    La Inseminación Artificial (IA) en caninos es una práctica que brinda grandes beneficios en la clínica reproductiva diaria. Esta biotecnología puede ser de moderada o alta complejidad, de bajo o mediano costo, según la técnica y el tipo de semen (fresco, refrigerado o congelado) utilizado. En cada caso brinda diferentes posibilidades, otorgando siempre grandes beneficios en la reproducción canina. Si se extrae semen de buena calidad, se lo acondiciona y maneja adecuadamente, se realiza la IA ...

  2. Hipoadrenocorticismo primario canino: reporte de caso

    Directory of Open Access Journals (Sweden)

    J. L. Granados

    2011-06-01

    Full Text Available Un canino macho Cocker Spaniel de 6 meses de edad fue presentado a la Clínica para Pequeños Animales de la Universidad Nacional de Colombia, con historia de vómito y diarrea de una semana de duración. El paciente presentaba hiperkalemia, y los electrocardiogramas realizados fueron compatibles con este hallazgo. El diagnóstico de hipoadrenocorticismo primario fue confirmado mediante la realización de una prueba de estimulación con ACTH. Posteriormente a la muerte súbita del paciente, el examen microscópico de las glándulas adrenales reveló cambios histológicos compatibles con laenfermedad de Addison. El hipoadrenocorticismo primario es un desorden endocrinopoco común que afecta principalmente pacientes caninos; está caracterizado por ladestrucción inmunomediada de las cortezas adrenales, lo cual conduce a deficienciade glucocorticoides, mineralocorticoides y hormonas sexuales adrenales. La historia delos pacientes afectados es variable y los signos clínicos son usualmente inespecíficos; laspruebas de laboratorio, por lo general, revelan hiperkalemia e hiponatremia, resultantesde la pérdida de la secreción de aldosterona. La historia, el examen clínico, la ecografíaabdominal y los hallazgos de laboratorio pueden indicar enfermedad de Addison, sinembargo, la prueba de estimulación con hormona adrenocorticotrópica (ACTH esconsiderada como la prueba de oro para el diagnóstico definitivo de la entidad. La enfermedadde Addison no tiene cura, pero puede ser manejada con terapia médica parareemplazar las deficiencias de mineralocorticoides y glucocorticoides.

  3. Hipoadrenocorticismo primario canino: reporte de caso

    Directory of Open Access Journals (Sweden)

    J. L. Granados

    2011-01-01

    Full Text Available Un canino macho Cocker Spaniel de 6 meses de edad fue presentado a la Clínica para Pequeños Animales de la Universidad Nacional de Colombia, con historia de vómito y diarrea de una semana de duración. El paciente presentaba hiperkalemia, y los electrocardiogramas realizados fueron compatibles con este hallazgo. El diagnóstico de hipoadrenocorticismo primario fue confirmado mediante la realización de una prueba de estimulación con ACTH. Posteriormente a la muerte súbita del paciente, el examen microscópico de las glándulas adrenales reveló cambios histológicos compatibles con la enfermedad de Addison. El hipoadrenocorticismo primario es un desorden endocrino poco común que afecta principalmente pacientes caninos; está caracterizado por la destrucción inmunomediada de las cortezas adrenales, lo cual conduce a deficiencia de glucocorticoides, mineralocorticoides y hormonas sexuales adrenales. La historia de los pacientes afectados es variable y los signos clínicos son usualmente inespecíficos; las pruebas de laboratorio, por lo general, revelan hiperkalemia e hiponatremia, resultantes de la pérdida de la secreción de aldosterona. La historia, el examen clínico, la ecografía abdominal y los hallazgos de laboratorio pueden indicar enfermedad de Addison, sin embargo, la prueba de estimulación con hormona adrenocorticotrópica (ACTH es considerada como la prueba de oro para el diagnóstico definitivo de la entidad. La enfermedad de Addison no tiene cura, pero puede ser manejada con terapia médica para reemplazar las deficiencias de mineralocorticoides y glucocorticoides.

  4. Genital Herpes

    Science.gov (United States)

    ... best way to prevent genital herpes is abstinence. Teens who do have sex must properly use a latex condom every time ... Date reviewed: February 2016 previous ... Boyfriend Has an STD Before We Have Sex? Telling Your Partner You Have an STD Contact ...

  5. Genital Herpes

    Science.gov (United States)

    ... to determine if you have herpes is a culture of the sore. A cotton swab is used to collect some of the fluid in the blister or cells on the sore, and this sample is grown in the laboratory. The sores must be fresh. A culture may not grow if the sores are dried ...

  6. Genital Herpes

    Science.gov (United States)

    ... condom. 28,29 The surest way to avoid transmission of STDs, including genital herpes, is to abstain from sexual contact, or to be in a long-term ... therapy as part of a strategy to prevent transmission, in addition to consistent condom use and ... recurrences. Health care providers with STD ...

  7. Neumonía por herpes virus simple tipo 1. Entidad infrecuente de difícil diagnóstico y mal pronóstico en trasplantados pulmonares

    OpenAIRE

    M.R. Mazzucco; Paladini, H.; F. Marinucci; Martínez, A.R.; Mela, M.; Wagner, G.

    2014-01-01

    La neumonía herpética es una rara enfermedad que afecta casi con exclusividad a personas con un déficit de inmunidad. Con frecuencia tiene un desenlace fatal. Su aparición está descrita en los primeros 2 meses luego del trasplante pulmonar, pero en nuestra experiencia se evidenció después de los 10 meses, 1 año y medio, 8 y 19 años. Describimos los hallazgos tomográficos detectados en 4 pacientes con trasplantes pulmonares que cursaron neumonía herpética. Presentaban fiebre, tos, expect...

  8. Genital Herpes (For Parents)

    Science.gov (United States)

    ... a Kidney Transplant Vision Facts and Myths Genital Herpes KidsHealth > For Parents > Genital Herpes Print A A A What's in this article? Symptoms Contagiousness Treatment Prevention Getting Help Genital herpes is a sexually transmitted disease (STD) that's usually ...

  9. HERPES GESTATIONIS.

    Directory of Open Access Journals (Sweden)

    Ivelina Yordanova

    2014-12-01

    Full Text Available Herpes gestationis, also known as pemphigoidgestationis (PG is an extremely rare autoimmune bullous dermatosis of the gestation and postpartum period. The disease was originally named herpes gestationis on the basis of the morphological herpetiform feature of the blisters. We report a 21-year-old woman, pregnant in the third trimester, who presented with a pruritic bullous cutaneous eruption of two weeks duration. The disease started with a red plaque in the abdominal area accompanied by mild itching. Soonafter, blisters appeared and affected almost the entire body. Physical examination revealed a primiparous woman in good general state, pregnant in 36 weeks of gestation. The skin changes affected the abdomen, back of the trunk, upper and lower extremities, hands and feet. They were manifested by a polymorphous eruption, consisting of erythematous urticaria-like plaques, small tense vesicles and multiple excoriations. Mucous membranes were not affected. Routine laboratory examinations were within normal limits. Direct immunofluorescence (DIF on perilesional skin showed linear deposition of IgG (++ and C3 (++ at the cutaneous basement membrane zone (BMZ. Indirect immunofluorescence (IIF on human esophagus substrate revealed circulating IgG anti-BMZ antibodies at a titer of 1:80. ELISABP180 NC16A was strongly positive. The diagnosis of PG was confirmed and a treatment with systemic methylprednisolone 60 mg/day was initiated, later gradually tapered to 20 mg/day, together with topical corticosteroids. As a result on the 10th day of the treatment we already achieved significant improvement with reduction of erythema and itching, absence of new skin lesions. The pregnancy ended in term with successful childbirth. No flare of the skin disease was observed in the puerperal period.

  10. Typical case: herpes zoster

    Directory of Open Access Journals (Sweden)

    Guilherme Cristianini Baldivia

    2015-04-01

    Full Text Available Summary The varicella zoster virus is the causative agent of herpes zoster and varicella. In herpes zoster, the virus dormant within dorsal root ganglia is reactivated, resulting in painful vesicular lesions overlying an erythematous base.

  11. Análisis de las propiedades inmunogénicas de las glicoproteínas de envoltura del virus de Distemper Canino expresadas en Pichia Pastoris

    OpenAIRE

    Tizzano, Marco Antonio

    2013-01-01

    El virus del distemper canino o CDV es un patógeno que afecta a los miembros de la familia Canidae, causando una enfermedad aguda, sistémica y frecuentemente mortal. Predispone al hospedador a las infecciones bacterianas secundarias y a posibles secuelas de tipo neurológico. La protección contra el CDV se logra a través de la vacunación. La mayoría de las vacunas se elaboran a partir de virus atenuado por pasaje en huevos embrionados o cultivos celulares. Sin embargo, estas vacunas han demost...

  12. Reabsorción radicular externa apical en incisivos y caninos superiores e inferiores sometidos a tratamiento de Ortodoncia en etapa inicial

    OpenAIRE

    Ruiz Reascos, Pamela Elizabeth

    2016-01-01

    La Reabsorción radicular externa apical es un proceso inflamatorio común asociado con el tratamiento de ortodoncia. El objetivo de este estudio fue comparar la magnitud de la RREA de los incisivos y caninos superiores e inferiores en pacientes sometidos a la fase inicial del tratamiento de ortodoncia con tres diferentes tipos de brackets. La muestra consistió en 23 casos de pacientes con edades comprendidas entre 12 y 27 años, fueron divididos aleatoriamente en 3 grupos. Grupo I (n=9; 5 mujer...

  13. ENFERMEDAD RENAL POLIQUISTICA ASOCIADA A LINFOMA EXTRANODAL EN UN CANINO

    Directory of Open Access Journals (Sweden)

    Diego Echeverry B

    2006-12-01

    Full Text Available Objetivo: Presentar el caso de un paciente canino, con enfermedad renal poliquística, asociada alinfoma extranodal. Materiales y métodos: Se estudió el caso de un paciente canino de raza SiberianHusky de 7 años de edad, al que se le encontraron múltiples nódulos renales bilaterales, condiagnóstico histopatológico de linfoma extranodal. Resultados: Se expone el caso clínico de unpaciente canino de raza Siberian Husky, que es presentado a consulta dermatológica por exhibirlesiones alopécicas multifocales. Una vez realizado el examen físico sistemático se evidenció demanera incidental nefromegalia. Los exámenes paraclínicos e histopatológicos aplicadosdemostraron la presencia de enfermedad renal poliquística asociada a linfoma extranodal, comoconsecuencia se presento falla renal crónica. Conclusiones: El linfoma extranodal renal es unaentidad patológica de rara presentación, clínicamente cursa con signos muy similares a otrasalteraciones tumorales, su diagnóstico suele ser histopatológico.

  14. Herpes Zoster

    Directory of Open Access Journals (Sweden)

    Hamid Ehsani-Nia

    2017-04-01

    Full Text Available History of present illness: A 26-year-old male presented to the emergency department with a burning rash over his left axilla and chest that started 2 days prior to presentation. The pain had been steadily worsening and was exacerbated by touch and the rubbing of his clothes over it. Patient denied fevers, chills, or weakness. Patient denied any past medical history, past surgical history or medications. He was unsure of his vaccination history and endorsed having chicken pox as a child. Significant findings: The patient was in mild distress, afebrile, with stable vital signs. His physical exam revealed an erythematous, grouped vesicular rash in various stages of progression including erythematous papules, clear vesicles, and pustular vesicles. Few lesions were scabbed over. No signs of crusting or scarring were appreciated. The distribution encompassed the entire left T4 dermatome both posteriorly and anteriorly. No other rashes were appreciated elsewhere on the body. Discussion: Herpes Zoster (HZ, also known as “shingles,” is a result of the reactivation Varicella Zoster Virus (VZV that emerges from latency in the sensory dorsal root ganglion. The reactivation causes the spreading of a classic rash of group vesicular lesions in various stages along the unilateral sensory dermatomal distribution over the first 3 days. Ulceration and crusting begin to occur after 3-5 days.1 The diagnosis is usually made clinically; however PCR testing of skin lesions is also available to differentiate between VZV, HSV1, and HSV2.2 The incidence of HZ increases with age due to immunosenesacence of cell mediated immunity, with the mean age between 43 and 53 years old.3 An immunocompromised state, due to factors like human immunodeficiency virus (HIV, medications, and autoimmune disease, also increases the incidence of HZ.4-6 A routine HIV screening in this patient was negative. He was prescribed oral acyclovir 800 mg, five times per day for five days.

  15. Herpes viral culture of lesion

    Science.gov (United States)

    ... have an active infection with herpes simplex virus. Herpes infections include genital herpes , cold sores on the lips or in the ... and the A.D.A.M. Editorial team. Genital Herpes Read more Herpes Simplex Read more NIH MedlinePlus ...

  16. Herpes associated erythema multiforme

    OpenAIRE

    K A Kamala; L Ashok; Rajeshwari G Annigeri

    2011-01-01

    Erythema multiforme is an acute and a self-limiting mucocutaneous hypersensitivity reaction triggered by certain infections and medications. One of the most common predisposing factors for erythema multiforme is infection with herpes simplex virus. Herpes associated erythema multiforme (HAEM) is an acute exudative dermatic and mucosal disease caused by the infecting herpes simplex virus. It has recurrence and idiorestriction, characterized by increasing of CD4+T leukomonocyte. This article re...

  17. TIPO Y FRECUENCIA DE AGRESIVIDAD CANINA A HUMANOS EN PACIENTES DE UNA CLÍNICA VETERINARIA EN LIMA.

    OpenAIRE

    Sal y Rosas M., Eduardo; Clínica de Animales Menores, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima-Perú.; Fernández P., Viviana; Clínica de Animales Menores, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima-Perú.; Lira M., Boris; Laboratorio de Fisiología Animal, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima; Santiani A., Alexei; Laboratorio de Reproducción Animal, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima

    2011-01-01

    El presente trabajo tuvo por finalidad conocer el tipo y frecuencia de agresividad del perro hacia el humano, así como las situaciones o contexto que las producen. Se encuestó a 405 propietarios de pacientes caninos, sin alteraciones neurológicas aparentes, de la Clínica de Animales Menores de la Facultad de Medicina Veterinaria de la Universidad Nacional Mayor de San Marcos, Lima. Se determinó que el 27.2% de los perros mostraron algún tipo de agresividad, mayormente de tipo leve y media, si...

  18. Herpes Zoster Oticus

    Science.gov (United States)

    ... Center (GARD) National Institute on Deafness and Other Communication Disorders (NIDCD) See all related organizations Publications Order NINDS Publications Definition Herpes zoster oticus, also called Ramsay Hunt Syndrome ...

  19. Herpes associated erythema multiforme.

    Science.gov (United States)

    Kamala, K A; Ashok, L; Annigeri, Rajeshwari G

    2011-10-01

    Erythema multiforme is an acute and a self-limiting mucocutaneous hypersensitivity reaction triggered by certain infections and medications. One of the most common predisposing factors for erythema multiforme is infection with herpes simplex virus. Herpes associated erythema multiforme (HAEM) is an acute exudative dermatic and mucosal disease caused by the infecting herpes simplex virus. It has recurrence and idiorestriction, characterized by increasing of CD4+T leukomonocyte. This article reports a case of HAEM in a 9-year-old girl, with a review of relevant literature, and discusses the pathophysiology and treatment of erythema multiforme triggered by herpes simplex virus.

  20. Herpes associated erythema multiforme

    Directory of Open Access Journals (Sweden)

    K A Kamala

    2011-01-01

    Full Text Available Erythema multiforme is an acute and a self-limiting mucocutaneous hypersensitivity reaction triggered by certain infections and medications. One of the most common predisposing factors for erythema multiforme is infection with herpes simplex virus. Herpes associated erythema multiforme (HAEM is an acute exudative dermatic and mucosal disease caused by the infecting herpes simplex virus. It has recurrence and idiorestriction, characterized by increasing of CD4+T leukomonocyte. This article reports a case of HAEM in a 9-year-old girl, with a review of relevant literature, and discusses the pathophysiology and treatment of erythema multiforme triggered by herpes simplex virus

  1. Los caninos incluidos y su relación con el patrón facial

    OpenAIRE

    Martínez González, Alicia

    2016-01-01

    Los caninos son dientes con una importancia vital en las arcadas desde el punto de vista estético y funcional. De todos es el canino maxilar, sin duda, el que es más importante. Se ha descrito como la piedra angular de la arcada maxilar, e indudablemente su longitud radicular y su excelente soporte óseo lo cualifican para este papel. La inclusión del canino maxilar, después de los terceros molares, supone un 2% de los pacientes de ortodoncia y tanto para su diagnóstico como para su tratam...

  2. Uso de tuberculina en caninos para buscar reservorios de Mycobacterium bovis

    OpenAIRE

    Carlos Bernal-Suarez; Sebastián Martínez-García; Roy José Andrade-Becerra

    2013-01-01

    Objetivo. Utilizar la prueba de tuberculina en caninos para buscar reservorios de Mycobacterium bovis. Materiales y métodos. Se utilizó la prueba comparada en los caninos que dieron positivo a la PPD ano-caudal, y la técnica de Ziehl-Neelsen en los animales dudosos, para corroborar el resultado. Resultados. Los caninos no son reservorios de la enfermedad, por tal razón, se sugiere utilizar pruebas diagnósticas más específicas para identificar el Mycobacterium en ellos.

  3. SEROPREVALENCIA DE Neospora caninum EN CANINOS DE DOS DISTRITOS DE LA PROVINCIA DE CHACHAPOYAS

    OpenAIRE

    Horna M., Segundo; Práctica privada; Chávez V., Amanda; Laboratorio de Microbiología y Parasitología Veterinaria, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima Perú.; Casas A., Eva; Laboratorio de Microbiología y Parasitología Veterinaria, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima Perú.; Serrano M., Enrique; Laboratorio de Microbiología y Parasitología Veterinaria, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima Perú.

    2013-01-01

    El Neospora caninum, parásito del canino, es ampliamente conocido como causante de abortos y mortalidad neonatal en bovinos a nivel mundial. El objetivo del presente estudio fue determinar la seroprevalencia de N. caninum en caninos de los distritos de Molinopampa y Leymebamba, provincia de Chachapoyas, Amazonas. Se evaluaron 142 sueros de caninos (63 de Molinopampa y 79 de Leymebamba) para la detección de anticuerpos mediante la prueba de Inmufluorescencia Indirecta (IFI). El 28.9 ± 7.5% de ...

  4. Manejo farmacológico de la hiperlipidemia en caninos

    Directory of Open Access Journals (Sweden)

    Anastasia Cruz Carrillo

    2011-06-01

    Full Text Available En los caninos, el aumento de los triglicéridos y del colesterol favorece la presentación de enfermedades que pueden ser graves para estos. Aunque la farmacología de los hipolipemiantes se ha desarrollado más en medicina humana, el médico veterinario debe conocer los fármacos útiles para controlar estas situaciones, ya que son comunes en ciertos pacientes. Por lo anterior, el objetivo de esta revisión fue hacer referencia a aquellos fármacos más usados en caninos para el control de las hiperlipidemias. Dentro de los fármacos grupos farmacológicos existentes se destacan las estatinas, los inhibidores del ácido fíbrico, los secuestrantes de ácidos biliares, la niacina, los inhibidores de la absorción de colesterol y el más reciente de uso veterinario, la dirlotapida. Todos ellos pueden ser incluidos dentro de los protocolos de manejo integral de pacientes con hiperlipidemias y obesidad.

  5. Valores de electrolitos, gases sanguíneos, nitrógeno ureico y glucosa en sangre venosa de caninos, ubicados a 2.600 msnm

    Directory of Open Access Journals (Sweden)

    Ernesto A. Dalmau Barros

    2008-12-01

    Full Text Available El presente trabajo aporta información útil sobre el estatus ácido-base a partir de 38 muestras de sangre venosa de caninos adultos en reposo, localizados a una altitud de 2.600 msnm. Los datos disponibles y actuales proceden, en su mayoría, de investigaciones realizadas en otros países en las que se hace referencia al tipo de trabajo del animal y al efecto de la altitud. Los datos obtenidos en este trabajo fueron comparados con la información reportada en caninos atletas y con las conclusiones de otras investigaciones. De acuerdo con los resultados de este estudio, en los caninos que viven en zonas a 2.600 msnm se presentan concentraciones de electrolitos, como el sodio (140,28 mmol/L y el cloruro (110,913 mmol/L, que resultan ser inferiores a los datos reportados por otras investigaciones, aunque los valores plasmáticos de sodio, cloruro, potasio y calcio ionizado no variaron en relación con otros estudios. Los valores de brecha aniónica y pH de la sangre no variaron en relación con los valores de referencia, mientras que la concentración de bicarbonato estuvo cerca al límite superior. Este último aspecto está relacionado con el aumento de la relación HCO3-:CO2d. La osmolalidad calculada estuvo cerca al límite inferior con una tendencia a la hiposmolalidad.

  6. Tumor venereo transmisible en caninos del area metropolitana de la ciudad de Mexico

    National Research Council Canada - National Science Library

    Pineda Cruz, Jocelyn; Romero Nunez, Camilo; Mendoza Martinez, German David; Garcia Contreras, Carmen Adelfa; Plata Perez, Fernando; Martinez Jimenez, Alejandro; Ramirez Duran, Ninfa

    2010-01-01

    .... Los perros muestreados fueron capturados en las calles. Un total de 717 muestras de perros sacrificados fueron evaluadas para determinar la presencia de tumor venereo transmisible canino, considerando solamente perros mayores de 1 ano...

  7. Tumores de glándula mamaria en caninos

    Directory of Open Access Journals (Sweden)

    Giovanni Torres

    2005-10-01

    Full Text Available De los animales de compañía, los caninos son los que sufren con mayor frecuencia tumores de glándula mamaria y dentro de ellos las hembras son las que contribuyen con el mayor número de casos. Cuando estos tumores se presentan en machos por lo general tienen características histológicas malignas. Para el diagnóstico histopatológico la clasificación que ha tenido mayor aceptación es la propuesta por Hampe and Misdorp. A través de muchos años de investigación en este campo se han descrito varios factores considerados como predisponentes, entre los cuales están: raza, sexo, edad, dentro de estos la que presenta mayor disparidad de conceptos es la raza ya que, según algunos autores, se puede ver influenciada por factores externos como la localización geográfica y el gusto de los propietarios por ciertas razas como animales de compañía. Otro hecho importante es la descripción de agentes causales: el invalance hormonal (estrógenos, progesterona, mutaciones genéticas, (gen supresor del tumor, protooncogenes y consumo de dietas ricas en grasas. Finalmente, es importante hacer énfasis en el hecho que del diagnóstico adecuado y pautas de tratamiento llevados a cabo por el médico veterinario clínico, depende el pronóstico y las expectativas de vida del paciente canino.

  8. Herpes Labialis: An Update.

    Science.gov (United States)

    Leung, Alexander K C; Barankin, Benjamin

    2017-01-01

    Herpes labialis is characterized by recurrent vesicular eruptions primarily on the lips and perioral skin. The condition is contagious, can cause significant discomfort/pain, and can have an adverse effect on the quality of life. To update the evaluation and treatment of herpes labialis. A PubMed search was completed in Clinical Queries using the key term "herpes labialis". Patents were searched using the key term "herpes labialis" from www.freepatentsonline.com. The diagnosis of herpes labialis is mainly clinical based on classic grouped lesions (papules, vesicles, ulcers) on the lip. Antiviral therapy shortens the duration of pain and discomfort, hastens healing, and reduces viral shedding. Thus, episodic treatment is warranted, especially if the patient desires treatment for cosmetic purposes or for relief of pain. Such treatment needs to be initiated promptly, ideally in the prodromal stage and no later than 48 hours from the onset of lesions to achieve optimal results. Chronic suppressive therapy with oral antiviral agents should be considered for patients with severe or frequent (six or more episodes per year) recurrences. Recent patents related to the management of herpes labialis are also discussed. For episodic treatment, oral antiviral agents, such as acyclovir (Zovirax), valacyclovir (Valtrex) and famciclovir (Famvir), are superior to topical antiviral therapy. Valacyclovir and famciclovir have greater oral bioavailability and are better absorbed than acyclovir, require less frequent dosing, but are more expensive and are not approved for children. Topical antiviral agents such as 5% acyclovir cream/ointment (Zovirax) ± hydrocortisone (Xerese), 1% penciclovir (Denavir) cream, and 50 mg Buccal Adhesive Tablet (ABT-50 mg) can also be used for episodic treatment of herpes labialis. These topical agents are not effective in the prevention of recurrent herpes labialis. For chronic daily suppressive therapy, oral antivirals are the treatment of choice

  9. Herpes Simplex Virus (Cold Sores)

    Science.gov (United States)

    ... Print Share Cold Sores in Children: About the Herpes Simplex Virus Page Content ​A child's toddler and ... Cold sores (also called fever blisters or oral herpes) start as small blisters that form around the ...

  10. Herpes zoster (shingles) disseminated (image)

    Science.gov (United States)

    Herpes zoster (shingles) normally occurs in a limited area that follows a dermatome (see the "dermatome" picture). In individuals with damaged immune systems, herpes zoster may be widespread (disseminated), causing serious illness. ...

  11. antibodies against Herpes simplex virus

    African Journals Online (AJOL)

    Herpes simplex virus (HSV) types -1 and -2 in pregnant women in. Port Harcourt, Nigeria. ... Cite as: Okonko IO, Cookey TI. Seropositivity and determinants of immunoglobulin-G (IgG) antibodies against Herpes simplex virus (HSV) ..... zadeh, Z. and Akbari, S. Seroepidemiology of Herpes. Simplex Virus Type 1 and 2 in ...

  12. Genital herpes - self-care

    Science.gov (United States)

    Herpes - genital - self-care; Herpes simplex - genital - self-care; Herpesvirus 2 - self-care; HSV-2 - self-care ... One type of herpes virus stays in the body by hiding within nerve cells. It can remain "asleep" (dormant) for a long time. ...

  13. Frecuencia de enfermedad periodontal y caries en caninos del Centro de Zoonosis de Bogotá

    OpenAIRE

    Rubiano, Deisy Katherine; Rojas, Diego Alejandro; Almansa, Jorge; Villalobos, María José; Montoya, David Ernesto; Urquijo, Guillermo Alfonso

    2014-01-01

    Introducción: el proyecto de investigación “Frecuencia de enfermedad periodontal y caries en caninos del Centro de Zoonosis de Bogotá” fue realizado en la Universidad Antonio Nariño, por el grupo de investigación “Quirón”, durante el 2011. Se determinó la frecuencia de presentación de enfermedad periodontal y caries en perros del Centro de Zoonosis de Bogotá. Materiales y métodos: se evaluaron 100 caninos que habían sido previamente eutanizados con pentobarbital sódico. Para establecer la pre...

  14. Comparación de los Niveles de Hormonas Tiroideas por Sexo en Caninos Adultos

    OpenAIRE

    Osorio, José Henry; Laboratorio de Bioquímica Clínica y Patología Molecular, Departamento de Ciencias Básicas de la Salud, Universidad de Caldas, Manizales; Suárez, Yirly Johanna; Laboratorio de Bioquímica Clínica y Patología Molecular, Departamento de Ciencias Básicas de la Salud, Universidad de Caldas, Manizales

    2016-01-01

    El objetivo del estudio fue establecer valores de referencia para las concentraciones séricas de la hormona estimulante de la tiroides (TSH) y tetrayodotironina libre (T4L) en caninos adultos de la zona de Caldas, Colombia y las posibles diferencias atribuidas al sexo. Las muestras de sangre se recolectaron de 78 caninos enteros (40 hembras y 38 machos mayores de un año), en ayunas, y se determinaron los niveles de TSH y T4L mediante inmunoensayo enzimático con kits comerciales. Los valores d...

  15. Neonatal herpes in Denmark 1977-1991

    DEFF Research Database (Denmark)

    Fonnest, G; de la Fuente Fonnest, I; Weber, Tom

    1997-01-01

    -1984 through 1984-1991. Three mothers (10%) had recurrent herpes at delivery, three (10%) had primary herpes, and five (17%) had oral herpes. Seven infants (23%) were delivered by Cesarean section. Nine (30%) only had cutaneous herpes, four (13%) had CNS herpes, nine (30%) had disseminated disease. Six (20...

  16. Herpes Zoster and Recurrent Herpes Zoster

    Science.gov (United States)

    Toyama, Nozomu; Daikoku, Tohru; Yajima, Misako

    2017-01-01

    Abstract Background. The incidence of recurrent herpes zoster (HZ) and the relationship between initial and recurrent HZ are not clear. Methods. The Miyazaki Dermatologist Society has surveyed ~5000 patients with HZ annually since 1997. A questionnaire regarding HZ and its recurrence was completed by the dermatologists. Results. A total of 34 877 patients with HZ were registered at 43 clinics between June 2009 and November 2015. Among 16 784 patients seen at 10 of the 43 clinics, 1076 patients (6.41%) experienced recurrence. Herpes zoster was more frequent in female than in male patients (5.27 vs 4.25 in 1000 person-years, P dermatome was observed in 16.3% of patients, and more frequently this occurred in the left side (P = .027). The number of HZ-experienced persons increased with age, and one third of the population had experienced HZ by the age of 80. Conclusions. Recurrent HZ was observed in 6.41% of patients, with a higher incidence in women. Moreover, HZ experience reduced the HZ incidence to 31.7% of the incidence in the HZ-naive population. PMID:28480280

  17. Genital Herpes: A Review.

    Science.gov (United States)

    Groves, Mary Jo

    2016-06-01

    Genital herpes is a common sexually transmitted disease, affecting more than 400 million persons worldwide. It is caused by herpes simplex virus (HSV) and characterized by lifelong infection and periodic reactivation. A visible outbreak consists of single or clustered vesicles on the genitalia, perineum, buttocks, upper thighs, or perianal areas that ulcerate before resolving. Symptoms of primary infection may include malaise, fever, or localized adenopathy. Subsequent outbreaks, caused by reactivation of latent virus, are usually milder. Asymptomatic shedding of transmissible virus is common. Although HSV-1 and HSV-2 are indistinguishable visually, they exhibit differences in behavior that may affect management. Patients with HSV-2 have a higher risk of acquiring human immunodeficiency virus (HIV) infection. Polymerase chain reaction assay is the preferred method of confirming HSV infection in patients with active lesions. Treatment of primary and subsequent outbreaks with nucleoside analogues is well tolerated and reduces duration, severity, and frequency of recurrences. In patients with HSV who are HIV-negative, treatment reduces transmission of HSV to uninfected partners. During pregnancy, antiviral prophylaxis with acyclovir is recommended from 36 weeks of gestation until delivery in women with a history of genital herpes. Elective cesarean delivery should be performed in laboring patients with active lesions to reduce the risk of neonatal herpes.

  18. Herpes simplex-encefalitis

    DEFF Research Database (Denmark)

    Jørgensen, Laura Krogh; Mogensen, Trine Hyrup

    2017-01-01

    Herpes simplex encephalitis (HSE) is a rare disease, although it is the most common form of sporadic encephalitis worldwide. Recently, studies have provided important new insight into the genetic and immunological basis of HSE. However, even in the presence of antiviral treatment, mortality...

  19. Evaluación de la altura de la cresta ósea de caninos impactados tratados ortodónticamente y caninos con erupción natural

    OpenAIRE

    Lobo Figueredo, Aura Mercedes; Pontificia Universidad Javeriana; Hernández Díaz, Liliana Alexandra; Pontificia Universidad Javeriana; Moreno Abello, Gloria Cristina; Pontificia Universidad Javeriana, Bogotá; Diaz Jaramillo, Iván Orlando; Pontificia Universidad Javeriana

    2014-01-01

    ANTECEDENTES: la oclusión funcional necesita que los dientes estén en completa alineación con un adecuado acople anterior y guía de protección canina. OBJETIVO: evaluar la altura de la cresta ósea alveolar después de realizar tracción ortodóntica de caninos impactados en el maxilar superior, comparados con un grupo control de caninos contralaterales erupcionados naturalmente en pacientes con edades entre 10 y 18 años. MATERIALES Y MÉTODOS: la muestra estuvo conformada por  10 caninos impactad...

  20. Imunidade celular em caninos neonatos - do nascimento ao 45° dia de idade

    Directory of Open Access Journals (Sweden)

    R.P. Klein

    2014-06-01

    Full Text Available O objetivo do presente trabalho foi acompanhar o desenvolvimento imunológico dos neonatos caninos, a fim de avaliar a imunidade celular pela análise dos leucócitos e linfócitos totais e das subpopulações de linfócitos T (CD4+ e CD8+ pela técnica de citometria de fluxo. Foram utilizados 30 cães neonatos de ambos os sexos, sem raça definida, aos três, 10, 17, 24, 31, 38 e 45 dias de idade. A contagem de leucócitos totais aos 45 dias (11.639±3.574 foi significativamente maior que no terceiro dia de idade (8.740±1.812 (P<0,05; não houve diferença entre a contagem total de linfócitos aos 45 dias em relação ao terceiro dia de idade. Quanto às subpopulações de LT CD4+ e LT CD8+, os percentuais de LT CD4+, aos três dias de idade (24,9±16,8%, foram inferiores quando comparados à média entre o 10°, o 24° e o 31°dia (35,5%, e os de CD8+, ao terceiro dia, menores em relação às médias do 10° e do 31° dia de idade. Pode-se concluir que as subpopulações de LT CD4+ e CD8+ sofrem oscilações durante o desenvolvimento pós-natal, sendo estas crescentes em relação aos níveis obtidos aos três dias de idade. A relação CD4+:CD8+ mostrou superioridade para o primeiro tipo celular, sendo que a maior relação entre CD4+ e CD8+ ocorreu no terceiro dia de idade. Com base nos resultados obtidos neste estudo, notaram-se as diferenças semanais nas populações linfocitárias, o que demonstra a dinâmica dessas células durante o período neonatal.

  1. Patrón de las alteraciones dentales asociadas a la impactación del canino maxilar por palatino

    OpenAIRE

    Olivera Aguilar, Esther

    2015-01-01

    La tesis doctoral se ha realizado para poder encontrar un método de diagnóstico precoz de la impactación del canino maxilar por palatino, mediante la detección temprana de otras alteraciones dentales asociadas y así poder aplicar tratamientos tempranos, que mejoren el pronóstico de la impactación del canino maxilar por palatino. La impactación del canino maxilar por palatino, supone la alteración del trayecto eruptivo del mismo, que lo conduce a la zona palatina. Los pacientes con esta altera...

  2. Diagnóstico de hipotiroidismo canino e hipertiroidismo felino 

    OpenAIRE

    Melián Limiñana, Carlos

    1999-01-01

    [ES] Evaluamos 854 animales para determinar la utilidad de nuevas pruebas hormonales para el diagnóstico de las enfermedades tiroideas más comunes en los animales de compañía: hipotiroidismo canino e hipertiroidismo felino.

  3. Do herpes e suas implicações audiológicas: uma revisao de literatura Herpes and its hearing implications: a literature review

    Directory of Open Access Journals (Sweden)

    Larissa Cristina Schuster

    2009-12-01

    Full Text Available TEMA: herpes e audiologia. OBJETIVO: realizar revisão teórica principalmente sobre os vírus herpes simples tipo 1, herpes simples tipo 2 e varicela-zoster, bem como sobre seus efeitos na audição humana. Esses se constituem nos tipos de vírus herpéticos humanos de maior relevância para a área da Audiologia dentro da ciência da Fonoaudiologia e, no entanto, são pouco conhecidos e estudados, especialmente no Brasil. MÉTODOS: realizou-se pesquisa em bases de dados eletrônicas nacionais e internacionais, incluindo SciELO, MEDLINE e LILACS, a partir da seguinte combinação de descritores: herpes simplex/zoster X hearing loss ou deafness. Foram selecionados estudos publicados desde a década de 90 até os dias atuais, relevando-se aqueles que contivessem maior valor informativo, contribuindo para os objetivos do presente trabalho. CONCLUSÃO: os vírus herpéticos estudados apresentam estreita relação com distúrbios auditivos, independentemente da idade em que o sujeito é acometido.BACKGROUND: herpes and audiology. PURPOSE: to promote a theoretical approach mainly on herpes simplex virus type 1, herpes simplex virus type 2 and varicella zoster virus, and their effects on human hearing. Although representing the most relevant human herpetic viruses for the area of Audiology within the Speech and Language Pathology Science, these viruses are little studied and known, especially in Brazil. METHODS: a research was carried out in national and international electronic databases, including SciELO, MEDLINE and LILACS, and using the following keyword combinations: herpes simplex/zoster X hearing loss or deafness. Studies published from the 90's until today were selected, revealing those that would contain the highest informative value, which would thus contribute for the objectives of this work. CONCLUSION: the studied herpetic viruses show strict relation with hearing disorders, regardless of the age in which the patient is affected.

  4. Diagnóstico clínico-microbiológico de otitis externa en caninos de Bogotá – Colombia

    Directory of Open Access Journals (Sweden)

    Adriana Pulido V.

    2010-12-01

    Full Text Available Objetivo. Evaluar clínica y microbiológicamente la implicación de Malassezia sp como agente etiológico de otitis externas en caninos. Materiales y métodos. Se obtuvieron 166 muestras de hisopados óticos de caninos con sintomatología y hallazgos clínicos compatibles con otitis externa durante el periodo comprendido entre julio – diciembre 2008. A partir de las muestras se realizaron cultivos bacteriológicos y micológicos e identificación de género mediante perfiles bioquímicos para cada unos de los microorganismos aislados. Los datos clínicos asociados a la patología fueron consignados en una base de datos y posteriormente analizados en el programa estadístico SPSS 17 Resultados. A partir de la 166 muestras obtenidas, 59% (98 de ellas fueron positivas para el cultivo bacteriológico con predominio de Staphylococcus sp 37% (61 y 73% (121 positivas para Malassezia. De las 121 levaduras aisladas 32.2% fue Malassezia pachydermatis. El análisis estadístico no evidenció diferencias significativas con respecto a las relaciones entre variables (género, edad, raza, tipo de oreja y respuesta inflamatoria por citología y el aislamiento de Malassezia sp. El nivel de significancia establecido para la prueba fue de 0.05%. Conclusiones. No se observaron asociaciones estadísticas entre las variables género, edad, raza frente a la otitis externa por Malassezia sp. Malassezia sp fue aislada en un 73% de los casos con otitis externa, con participación de diferentes agentes bacterianos especialmente Staphylococcus sp.

  5. TPLO--osteotomia niveladora del plato tibial. Tratamiento quirurgico para la rotura del ligamento cruzado anterior en caninos

    National Research Council Canada - National Science Library

    Berrio Betancur, Alina Maria; Ochoa Velez, Juan Jose

    2009-01-01

    La rotura del ligamento cruzado anterior, como consecuencia de trauma o de procesos degenerativos en la articulacion de la rodilla, es una de las causas mas comunes de claudicacion en miembro posterior en caninos...

  6. Determinacion del pronostico en pacientes que presentan caninos maxilares impactados de la Facultad de Odontologia de la Universidad de Antioquia

    National Research Council Canada - National Science Library

    Ramirez Ossa, Diana Milena; Upegui Zea, Juan Carlos; Echeverri Gonzalez, Elizabeth; Restrepo Narvaez, Leidy Marcela

    2009-01-01

    ...: se hizo valoracion clinica de los pacientes con impactacion de caninos maxilares y se tomaron, escanearon y trazaron digitalmente una radiografia panoramica y tres periapicales de cada diente objeto...

  7. Estabilidade molecular de uma amostras vacinal de Coronavírus canino após passagens seriadas em células A72

    Directory of Open Access Journals (Sweden)

    Iracema Nunes de Barros

    2017-05-01

    Full Text Available O Coronavírus canino (CCoV ocorre como tipos I e II e infecta cães, levando principalmente a enterite, apesar do tipo II já ter sido associado à infecção generalizada e altamente letal. Uma vacina de CCoV-II inativada produzida em células caninas A72 é disponível mundialmente e largamente utilizada, apesar da sua estabilidade molecular após passagens seriadas de sementes vacinais ser desconhecida. Este artigo relata a evolução da amostra vacinal CCoC-II 1-71 em células A-72 com base em sequenciamento parcial do gene S, demonstrando predomínio de evolução neutra e a ocorrência de quaro sítios sob seleção purificante. Portanto, amostras de CCoV-II adaptadas a cultivos celulares podem ser estáveis geneticamente após passagens seriadas em uma mesma linhagem celular devido à existência de uma relação estável vírus-hospedeiro.

  8. Chronic herpes simplex virus encephalitis in childhood.

    NARCIS (Netherlands)

    Leen, W.G.; Weemaes, C.M.R.; Verbeek, M.M.; Willemsen, M.A.A.P.; Rotteveel, J.J.

    2006-01-01

    Although herpes simplex virus is a major cause of acute encephalitis in childhood, chronic herpes simplex virus encephalitis has only rarely been reported. This report presents a case of chronic herpes simplex virus encephalitis in a 6-year-old female. Diagnosis was based on the detection of herpes

  9. DE LA RABIA HUMANA DE ORIGEN CANINO Y OTRAS VERGÜENZAS

    Directory of Open Access Journals (Sweden)

    Nelson Alvis G

    2006-12-01

    por rabia humana del período(17casos; seguida de la región occidental (5 casos, la Orinoquia (3 casos, la Amazonía (2casos y la Región Central, un sólo caso en el 2003. Es decir todo estaba anunciado.Los muertos se presentaron como consecuencia de la mordedura de perros infectados con elvirus de la enfermedad, en diciembre de 2006. El Instituto Nacional de Salud confirmó loscasos y estimó éste como el brote mas grave, luego del ocurrido entre mayo y julio del 2004en el que se notificaron 14 casos en el Bajo Baudó, por mordedura de murciélago. Cabeaclarar que se trata de un tipo de virus distinto al transmitido por caninos.Según informes de la Secretaría de Salud de Santa Marta, al parecer las víctimas fueronmordidas en septiembre. La primera falleció el 5 de noviembre, la segunda 20 días despuésy la tercera el 16 de enero. Uno de los indicadores a partir de los cuales deben generarsealertas es la presencia de rabia animal. Ya para el 2005, el departamento del Magdalenamostraba el mayor número de casos reportados en el país: 18 de los 97 registrados.En el informe se destaca a pie de pagina: “El grupo evaluador, en virtud de razonesepidemiológicas, operativas y políticas considera necesario resaltar la urgencia de estarecomendación considerando que la situación de rabia transmitida por el perro en losDepartamentos de la Costa es un asunto que requerirá la intervención directa de las masaltas autoridades nacionales para evitar casos humanos prevenibles que se ven comoaltamente probables en un futuro próximo de persistir la situación actual. El virus de la rabianecesita de la existencia de perros no vacunados para sostenerse en la población caninae inesperadamente afectar a una persona si no se la trata oportunamente. El deficienteesquema de vacunación que se verificó en los departamentos de la costa, sumado asituaciones ecológicas particulares y a deficiencias en el control de focos, permite al viruscircular y manifestarse – de cuando en

  10. Neonatal herpes in Denmark 1977-1991

    DEFF Research Database (Denmark)

    Fonnest, G; de la Fuente Fonnest, I; Weber, Tom

    1997-01-01

    BACKGROUND: To prevent neonatal herpes, women in labor with genital herpes infection are still delivered by Cesarean section. This policy is currently being debated. The aim of this study was to determine the incidence of neonatal herpes in Denmark and to evaluate the prevention practice. METHODS......: All newborns with perinatal herpes in Denmark 1977-1991 were identified from hospital-records. RESULTS: Of 862,298 deliveries 136 possible cases were found but only 30 (22%) fulfilled the criteria for neonatal herpes. The incidence increased from 2.36 to 4.56 per 100,000 live births during 1977......-1984 through 1984-1991. Three mothers (10%) had recurrent herpes at delivery, three (10%) had primary herpes, and five (17%) had oral herpes. Seven infants (23%) were delivered by Cesarean section. Nine (30%) only had cutaneous herpes, four (13%) had CNS herpes, nine (30%) had disseminated disease. Six (20...

  11. Contribución a la histopatologia del distemper canino

    Directory of Open Access Journals (Sweden)

    E. Encinas

    1945-09-01

    Full Text Available En un caso de distemper canino el examen anatómico del sistema nervioso ofrece cambios elementales y estructurales sistematizados, no revelados hasta ahora. El hecho de que determinadas unidades estructurales, en evidente relación con los espacios sub-aracnoideos, hayan sido preferentemente comprometidas, en contraste con otras que se han mantenido indemnes por estar fuera de la influencia de aquellos y de su liquor circulante, hace sospechar que aparte de la vía sanguínea, sea el liquor uno de los vehículos del agente infectante. Pero lo que esta influencia no explica es el cambio parcial de las células nerviosas de ciertas zonas, de las formaciones ammónicas, Fig. Nº 44, ni la alteración de los componentes celulares de una unidad arquitectural, de lámina Vª de la corteza, por ejemplo. Para esta especie de variación no cabe al presente, mas que la sospecha, a menudo comprobada, de que determinadas unidades celulares o arquitecturales, poseen cierto grado de vulnerabilidad bis a bis de los agentes agresores. Y esta opinión tan a menudo verificada en la patología humana no tiene porqué no ser extendida a los cambios en los tejidos nerviosos de animales inferiores. El asta de Ammón humana ha sido con frecuencia estudiada en múltiples procesos patológicos, comprobándose la manera fácil con que agentes vulnerantes la modifican y lesionan, pero, que sepamos, no se han hecho estudios detenidos de ella en procesos sospechosos virulentos como en las encefalitis, ni en aquellos debidos a bacterias. En estos aspectos como en otros de las investigaciones biológicas parece que todos los recursos estuvieran dirigidos a verificar hallazgos ya realizados, o a comprobar sus variaciones, más nó a ir al encuentro de nuevos hechos de información mayor, y de provecho para el conocimiento, Asunto sería de investigar por ejemplo si en la encefalitis humanas ocurren alteraciones semejantes a las mencionadas en este trabajo (de distemper, y, si

  12. CARCINOMA COMPLEJO DE GLÁNDULA MAMARIA, ACANTOMA QUERATINIZANTE INFUNDIBULAR Y MASTOCITOMA TIPO III EN UN CANINO

    National Research Council Canada - National Science Library

    Ochoa Amaya, Julieta; Ciuoderis Aponte, Karl; Pedraza Castillo, Natalia

    2009-01-01

    ...) is the less common tumor of the follicular neoplasms, in contrast, mastocytoma (CM) is the most common tumor of mesenchymal tumors in dogs as well as a canine mammary tumors are the most common tumors in female...

  13. Carcinoma complejo de glándula mamaria,acantoma queratinizante infundibular y mastocitoma tipo III en un canino

    National Research Council Canada - National Science Library

    Pedraza Castillo, Natalia; Ciuoderis Aponte, Karl; Ochoa Amaya, Julieta

    2009-01-01

    ..., esta asociada con el desarrollo de los tumores mamarios tanto en perras como en gatas. El riesgo relativo para el desarrollo de tumores mamarios se relaciona con el numero de ciclos estrales que la perra ha experimentado, el riesgo para aquellas hembras castradas antes del primer celo o despues del primer o segundo estro corresponde a 0.05, ...

  14. Avulsión de canino y subluxación del primer premolar superiores derechos

    OpenAIRE

    Berástegui, Esther

    1996-01-01

    Se presenta un caso clínico de avulsión de canino y subluxación del primer remolar, superiores derechos, secundario a traumatismo por piedra lanzada al aire. El tiempo extraoral fue de cuatro horas en medio seco. Se trató con reimplante, ferulización y tratamiento endodóncico. Los controles posteriores a los cuatro años del tratamiento mostraron la evolución favorable del caso.

  15. Estudio del perfil lipídico canino por edad y sexo

    Directory of Open Access Journals (Sweden)

    José Henry Osorio

    2012-06-01

    Full Text Available Este trabajo se propone comparar el perfil lipídico en caninos criollos o sus cruces en el departamento de Caldas, Colombia, y analizar la correlación entre las cantidades lipídicas del suero de seis grupos. Se obtuvieron muestras de sangre de 156 caninos en estado de ayuno, diferenciados por sexo y edad (32 machos y 34 hembras menores de un año, y 42 machos adultos y 48 hembras mayores de un año; se determinaron triglicéridos, colesterol total y el colesterol de las lipoproteínas de alta densidad mediante el método enzimático colorimétrico. El colesterol de las lipoproteínas de muy baja densidad y de baja densidad se determinó usando las fórmulas de Friedewald. Las medias ± desviación estándar para colesterol total, triglicéridos y colesterol de las lipoproteínas de alta, muy baja y baja densidad en mg/dL fueron de: 214,91 ± 75,3; 50,01 ± 42,5; 133,73 ± 40,11; 10, 00 ± 8,51; 71,17 ± 57,12 respectivamente. Para el resto de los grupos, los triglicéridos, el colesterol VLDL y el colesterol LDL no fueron significativos (p ≥ 0,05. El colesterol HDL en los caninos jóvenes y adultos presentó un valor de 0,0377 en el valor p del test F, que mostró diferencia significativa (p < 0,05. En los resultados mostrados por los caninos jóvenes, especialmente los machos, se observa que estos presentan un colesterol total y un colesterol HDL más altos si se compara con los adultos.

  16. Retração rápida de caninos

    Directory of Open Access Journals (Sweden)

    Paulo Renato Carvalho Ribeiro

    Full Text Available INTRODUÇÃO: a retração rápida de caninos por distração do ligamento periodontal é uma técnica de movimentação dentária que permite o fechamento de espaço da extração de primeiros pré-molares em um intervalo de duas ou três semanas, proporcionando uma redução significativa no tempo do tratamento ortodôntico. OBJETIVO: apresentar modificações propostas na técnica cirúrgica original e no posicionamento dos distratores. CONCLUSÕES: a retração rápida de caninos é uma técnica que proporciona uma redução significativa no tempo de tratamento ortodôntico. A modificação na técnica cirúrgica proporcionou maior velocidade e segurança ao ato cirúrgico. O distrator posicionado por palatina, no mínimo, proporcionou a preservação da tábua óssea vestibular e evitou a vestibularização dos caninos.

  17. EVALUACIÓN DE TRES METODOLOGÍAS DE RECUPERACIÓN DE EMBRIONES EN CANINOS UTILIZANDO UN MODELO POSTMORTEM

    Directory of Open Access Journals (Sweden)

    Claudia Jiménez E

    2008-12-01

    Full Text Available Objetivo. Evaluar tres técnicas de recuperación de embriones, utilizando como modelos de simulación oocitos desnudos introducidos en úteros recuperados post–mortem. Materiales y métodos. Se introdujeron 10 oocitos en el extremo ovárico de cada cuerno. El tratamiento 1 (T1 consistió en realizar una punción a nivel del extremo ovárico de cada cuerno para introducir el medio de lavado. Se incidió la base de cada cuerno para ubicar un catéter TOMCAT 8-Fr, recuperando el medio en una caja de petri. En el tratamiento 2 (T2 se realizó una punción en el extremo ovárico de cada cuerno pero la recuperación de los oocitos se realizó con un catéter de 56 cm de longitud que se pasó transcervicalmente hasta la base de cada cuerno. En el tratamiento 3 (T3 se utilizó el mismo tipo de catéter por vía transcervical y el lavado y la recuperación se realizó a través del mismo catéter. Resultados. El número de estructuras recuperadas fue de 7.3 ± 2.4 (73% para el T1; 8.5 ± 1.9 (85% para el T2 y de 5.8±2.2 (58% para el T3. La tasa de recuperación fue similar para T1 y T2, pero significativamente mayores que para el T3 (p>0.01. Conclusiones. Las técnicas que se proponen son menos invasivas y tienen resultados comparables a otros estudios donde realizan histerectomía y laparotomía. Con este tipo de técnicas, se disminuye el trauma generado por incisiones quirúrgicas y la posible generación de adherencias. Adicionalmente permitirían realizar recuperaciones de embriones no quirúrgicas en caninos.

  18. Prevalencia de anticuerpos para Trypanosoma cruzi en caninos de dos municipios endémicos de Boyacá

    Directory of Open Access Journals (Sweden)

    Diego Manrique Abril

    2012-04-01

    Full Text Available Objetivo. evaluar la prevalencia de anticuerpos anti Trypanosoma cruzi (T. cruzi en una muestra de caninos domésticos residentes en dos municipios endémicos. Materiales y métodos. Se tomaron muestras séricas de 20 caninos procedentes de hogares donde residen mujeres gestantes seropositivas y 40 perros habitantes de hogares de mujeres gestantes seronegativas en Miraflores y Moniquira, Boyacá. El análisis se realizó mediante prueba diagnóstica rápida dipstick de InBios. Resultados. Se encontró prevalencia del 16.7% en Moniquirá y del 13.3% Miraflores respectivamente con una prevalencia general del 15% en los dos municipios. Se halló riesgo 3 veces mayor de que ocurra la infección en caninos, en los hogares donde residen gestantes seropositivas; además la infestación por pulgas y garrapatas en el animal, hábitat cercano a la vivienda, se relacionan con mayor seropositividad en el canino. Conclusiones. La raza, el sexo, la presencia de aves en la casa y al examen clínico general son considerados factores pronósticos en en la infección por Trypanosoma cruzi en caninos. Como factores protectores se identificó la desparasitación y vacunación de los animales.

  19. Efeitos da expansão rápida da maxilia sobre o posicionamento dos caninos superiores potencialmente impactados na fase da dentadura mista

    OpenAIRE

    Luciana Bocudo Hoffelder

    2016-01-01

    O estudo objetivou avaliar as alterações propiciadas pela expansão rápida da maxila (ERM) na trajetória de erupção dos caninos superiores na fase da dentadura mista. Foram selecionados caninos no estágio 8 de Nolla e que estivessem localizados nos setores II, III ou IV e distribuídos em 3 Grupos: Grupo 1 (G1) - Caninos Potencialmente Impactados com Expansão (CPIE) (n=49), Grupo 2 (G2) – Caninos em Normalidade Sem Expansão (CNSE) (n=54) e Grupo 3 (G3) – Caninos em Normalidade Com Expansão (CNC...

  20. Influência do tipo de retentor intra-radicular e da radioterapia na deformação, resistência e padrão de fratura de diferentes dentes tratados endodonticamente

    OpenAIRE

    Castro, Carolina Guimarães

    2009-01-01

    O objetivo deste estudo laboratorial foi avaliar a influência do tipo de retentor intra-radicular e do efeito da radioterapia na deformação, resistência e padrão de fratura de diferentes tipos de dentes humanos tratados endodonticamente. Foram selecionados 160 dentes humanos (n=40): In, incisivos; Ca, caninos; Pm, pré-molares bi-radiculares e Mo, molares bi-radiculares. Os dentes tiveram foram tratados endodonticamente. Metade dos dentes de cada grupo (n= 20) foram submetido...

  1. Predicción de la Inclusión de Caninos Superiores en una Población Infantil

    OpenAIRE

    Gascón Pellicer, Jordi

    2015-01-01

    La tesis doctoral se ha realizado debido a la gran prevalencia de inclusión de caninos superiores en la población general. En la segunda fase de recambio dentario, el diente que provoca más problemas eruptivos es el canino permanente superior. Si este diente altera su trayecto eruptivo, el resultado puede ser una erupción ectópica del mismo o su retención por palatino. En ambos casos, el paciente necesitará tratamiento ortodóncico que suele ser largo y complejo. Por ese motivo, sería importan...

  2. Prevalencia de anticuerpos para Trypanosoma cruzi en caninos de dos municipios endémicos de Boyacá

    OpenAIRE

    Diego Manrique Abril; Manrique Abril; Myriam Lorca H.; Juan Ospina D.

    2012-01-01

    RESÚMENObjetivo. evaluar la prevalencia de anticuerpos anti Trypanosoma cruzi (T. cruzi) en una muestra de caninos domésticos residentes en dos municipios endémicos. Materiales y métodos. Se tomaron muestras séricas de 20 caninos procedentes de hogares donde residen mujeres gestantes seropositivas y 40 perros habitantes de hogares de mujeres gestantes seronegativas en Miraflores y Moniquira, Boyacá. El análisis se realizó mediante prueba diagnóstica rápida dipstick de InBios. Resultados. Se e...

  3. [Herpes associated erythema multiforme: a case report].

    Science.gov (United States)

    Li, Qing-fu; Li, Duo; Zhou, Hong-mei; Lin, Mei

    2008-08-01

    Herpes associated erythema multiforme (HAEM) is an acute exudative dermatic and mucosal disease caused by infecting herpes simplex virus. It has recurrence and idiorestriction, characterized by increasing of CD4+T leukomonocyte. This article reports a case of herpes associated erythema multiforme, and by way of reviewing relevant literature, discusses the possible mechanism, diagnosis, treatment and prognosis of HAEM.

  4. Molecular diagnosis of visceral herpes zoster

    NARCIS (Netherlands)

    de Jong, M. D.; Weel, J. F.; van Oers, M. H.; Boom, R.; Wertheim-van Dillen, P. M.

    2001-01-01

    Patients with disseminated herpes zoster may present with severe abdominal pain that results from visceral involvement of varicella-zoster-virus infection. In the absence of cutaneous eruptions of herpes zoster, visceral herpes zoster is extremely difficult to diagnose. This diagnostic difficulty

  5. Retração rápida de caninos Rapid canine retraction

    Directory of Open Access Journals (Sweden)

    Paulo Renato Carvalho Ribeiro

    2011-02-01

    Full Text Available INTRODUÇÃO: a retração rápida de caninos por distração do ligamento periodontal é uma técnica de movimentação dentária que permite o fechamento de espaço da extração de primeiros pré-molares em um intervalo de duas ou três semanas, proporcionando uma redução significativa no tempo do tratamento ortodôntico. OBJETIVO: apresentar modificações propostas na técnica cirúrgica original e no posicionamento dos distratores. CONCLUSÕES: a retração rápida de caninos é uma técnica que proporciona uma redução significativa no tempo de tratamento ortodôntico. A modificação na técnica cirúrgica proporcionou maior velocidade e segurança ao ato cirúrgico. O distrator posicionado por palatina, no mínimo, proporcionou a preservação da tábua óssea vestibular e evitou a vestibularização dos caninos.INTRODUCTION: Rapid canine retraction through distraction of the periodontal ligament is a tooth movement technique that allows the closure of first premolar extraction space within a period of two to three weeks while providing significant reduction in orthodontic treatment time. OBJECTIVE: To propose changes in the original surgical technique and in the placement of distractors. CONCLUSIONS: Rapid canine retraction is a technique that provides significant reduction in orthodontic treatment time. Changes in the surgical technique provided greater speed and safety in surgery. As a minimum benefit, when positioned palatally, distractors helped to preserve the buccal bone plate and prevented canine proclination.

  6. Seroprevalencia de Leptospira spp en caninos y humanos de tres barrios de Tunja, Colombia

    Directory of Open Access Journals (Sweden)

    Soledad Bermúdez C.

    2010-12-01

    Full Text Available Objetivo. Establecer la seroprevalencia de Leptospira spp., en la población canina y humana de barrios marginados en la ciudad de Tunja. Materiales y métodos. Se muestrearon 61 sueros caninos en los barrios marginales de la ciudad, parlelamente se muestrearon y encuestaron 46 humanos propietarios de las mascotas. Para el procesamiento de las muestras se empleó la técnica de microaglutinación-lisis (MAT para seis serotipos de Leptospira spp. Resultados. Se encontró una seropositividad del 67.2% en la población de caninos muestreada, la seroprevalencia por serovares arrojada fue del 14.8% para L. icterohemorrágica; 8.2% para L. pomona; 9.85% para L. hardjo; 18% para L. canicola y 6.6% para L. automnalis y 9.8% para L. sejroë. Para los humanos la prevalencia fue del 21.7%, por serovares se encontró que L. automnalis tiene 4.35%; L. hardjo 2.17%, L. sejroë tiene 6.52%, L. icterohaemorragiae 6.52% y L. canicola 2.17%. Conclusiones. Estos resultados demostraron una gran problemática de alto impacto ya que en contraste con prevalencias de otros municipios de Colombia, mostró una elevada positividad en esta zona y dejan una gran preocupación por una rápida diseminación que podria suceder debido al contacto entre los diferentes vectores como lo roedores y caninos.

  7. Classificação citológica dos linfomas caninos

    Directory of Open Access Journals (Sweden)

    Sara Maria de Carvalho e Suzano

    2010-02-01

    Full Text Available Os linfomas estão entre as neoplasias mais frequentes na espécie canina. Do ponto de vista etiológico, epidemiológico, clínico, morfológico e imunofenotípico, os linfomas caninos apresentam muitas semelhanças com os linfomas não-Hodgkin humanos e os esquemas de classificação destes têm sido utilizados na espécie canina. O objetivo do presente trabalho foi aplicar aos linfomas caninos as classificações de Kiel, Working Formulation e Fournel-Fleury et al. (1994, em material colhido pelo método da PAAF (Punção Aspirativa por Agulha Fina. De acordo com a Classificação de Kiel, 61,02% (36 casos das neoplasias se enquadram como de grau alto 38,98% (23 casos como de grau baixo. Segundo a Classificação da Working Formulation, 11,86% (sete casos foram classificados linfomas de grau baixo, 61,02% (36 casos de grau intermediário e 27,12% (16 casos de grau alto. Utilizando a classificação proposta por Fournel-Fleury et al. (1994, 38,98% (23 casos dos animais que apresentaram linfomas de grau baixo e 61,02% (36 casos de grau intermediário ou alto. Concluindo, a PAAF é um método de diagnóstico que pode ser empregado na classificação dos linfomas caninos. A classificação que mostrou melhores resultados foi a de Kiel, que tem por característica principal a ênfase nos achados citológicos.

  8. Aplicação do inibidor da tirosina cinase, fosfato de toceranib, no mastocitoma canino

    OpenAIRE

    Sousa, Olga Violante Vieira de

    2014-01-01

    Dissertação de Mestrado Integrado em Medicina Veterinária, Ciências Veterinárias O mastocitoma é uma neoplasia comum no cão, representando cerca de 7 a 21% de todas as neoplasias cutâneas e 11 a 27 % de todos os tumores malignos nesta espécie. O seu comportamento biológico é extremamente variável, podendo tratar-se de uma simples massa perfeitamente localizada ou de uma grave doença metastática. Apesar das inúmeras pesquisas efetuadas, a etiopatogenia do mastocitoma canino não se encont...

  9. Signos neurológicos asociados a pacientes caninos con linfoma

    Directory of Open Access Journals (Sweden)

    Adriana Patricia Suraniti

    2012-06-01

    Full Text Available El cáncer altera las estructuras o las funciones de órganos vecinos por su simple presencia, con las consiguientes manifestaciones clínicas; pero también produce efectos nocivos en órganos distantes. Estas alteraciones clínicas inducidas por la acción no invasiva del tumor son de gran diversidad clínica y se conocen como síndromes paraneoplásicos. En el presente trabajo se describen cuatro casos de pacientes caninos con alteraciones neurológicas asociadas a linfadenopatía superficial generalizada.

  10. Prevalencia de helmintos intestinales en caninos del departamento del Quindío.

    OpenAIRE

    María Isabel Giraldo; Nora Lizeth García; Jhon Carlos Castaño

    2005-01-01

    Introducción. Los helmintos intestinales son agentes patógenos que afectan animales domésticos y que a través de ellos pueden infectar humanos. Objetivo. El objetivo del trabajo fue determinar la prevalencia de helmintos intestinales en perros con dueño del departamento del Quindío. Materiales y métodos. Estudio descriptivo prospectivo. Se aplicó una encuesta epidemiológica a los propietarios de los perros. Se recolectaron muestras de heces de los caninos registrados en la jornada de vacunaci...

  11. Prevalencia de parasitos zoonoticos de origen canino en un parque público

    OpenAIRE

    Sinchi Sinchi, Bertha Claudina

    2017-01-01

    El presente estudio determinó la prevalencia de parasitos zoonoticos de origen canino en el Parque de la Madre de la ciudad de Cuenca, mismo que fue dividido en diferentes zonas (juegos infantiles, áreas verdes, cancha, GYM público, planetario), de las cuales se tomaron muestras de heces al azar y de esta manera se levantó información sobre el nivel de contaminación de dicho parque. The present study determined the prevalence of canine zoonotic parasites in the Mother Park of the city of C...

  12. Herpes Zoster Ophthalmicus in HIV/AIDS

    Directory of Open Access Journals (Sweden)

    Boateng Wiafe MD MSc

    2003-01-01

    Full Text Available Herpes zoster is a common infection caused by the human herpes virus 3, the same virus that causes chickenpox. It is a member of herpes viridae, the same family as the herpes simplex virus, Epstein- Barr virus, and cytomegalovirus. Herpes zoster ophthalmicus occurs when a latent varicella zoster virus in the trigeminal ganglia involving the ophthalmic division of the nerve is reactivated. Of the three divisions of the fifth cranial nerve, the ophthalmic is involved 20 times more frequently than the other divisions.

  13. Influência da expansão rápida da maxila na rizólise dos caninos decíduos usados como ancoragem Influence of rapid maxillary expansion on the root resorption of primary canines used as anchorage

    Directory of Open Access Journals (Sweden)

    Omar Gabriel da Silva Filho

    2009-10-01

    Full Text Available OBJETIVOS: o presente estudo radiográfico, retrospectivo e longitudinal objetivou determinar se a ancoragem do aparelho expansor fixo tipo Haas, modificado para as dentaduras decídua e mista, interfere na velocidade de rizólise e esfoliação dos caninos decíduos. MÉTODOS: foi feita uma avaliação quantitativa da rizólise do canino decíduo mediante a medição do comprimento coroa-ápice dos caninos decíduos superiores, dos lados direito e esquerdo. Para essa avaliação, 24 crianças submetidas à expansão rápida da maxila (ERM na dentadura decídua ou no início da dentadura mista foram comparadas com 15 crianças que não passaram por esse procedimento. A medição do comprimento coroa-ápice dos caninos decíduos foi realizada com o programa computadorizado CEF-X Cefalometria Digital, produzido pela CDT Informática, que permitiu calibrar o tamanho dos dentes pela uniformização das imagens radiográficas digitalizadas. RESULTADOS: os dados estatísticos revelaram que não houve diferença na velocidade de rizólise dos caninos decíduos entre as crianças do grupo controle e as do grupo submetido à ERM. CONCLUSÕES: é possível inferir que o aparelho expansor fixo tipo Haas ancorado em dentes decíduos não influencia a rizólise dos caninos decíduos usados como ancoragem.AIM: The current radiographic, retrospective longitudinal study aim was to demonstrate whether the Haas fixed appliance, modified for the primary and mixed dentitions, interferes in the velocity of the root resorption and exfoliation of the primary canines. METHODS: It was evaluated the amount of root resorption of primary canines on the basis of measurements of the apex-crown length of right and left upper primary canines. For this measurement twenty-four children submitted to rapid maxillary expansion (RME in the primary and mixed dentition were compared to 15 children who did not undergo such a procedure. The measurement of the apex-crown length of the

  14. Esporotricose óssea e cutânea em canino

    Directory of Open Access Journals (Sweden)

    Isabel Martins Madrid

    2007-12-01

    Full Text Available A esporotricose é uma micose subcutânea causada pelo fungo dimórfico Sporothrix schenckii. Este artigo descreve o primeiro caso de esporotricose óssea e cutânea, em canino, na cidade de Pelotas, Rio Grande do Sul. O animal apresentava lesões ulceradas e crostosas, há aproximadamente três anos no plano nasal e membro torácico direito, dispnéia e apatia. Para confirmação do diagnóstico, foram realizados exames micológico, histopatológico, radiológico e hematológico. O animal foi tratado durante três meses com 10mg/kg de itraconazol, por via oral, obtendo-se a cura das lesões. Este estudo alerta clínicos de pequenos animais para a ocorrência desta micose em caninos na região de Pelotas, RS.

  15. Tres casos de síndrome granuloma leproide canino en Tandil, Buenos Aires, Argentina

    Directory of Open Access Journals (Sweden)

    María C. Jorge

    2009-01-01

    Full Text Available El síndrome granuloma leproide canino (SGLC es una afección nodular piogranulomatosa que afecta al tejido cutáneo y subcutáneo de los caninos, ocasionado por Mycobacterium sp. Las lesiones se caracterizan por nódulos simples o múltiples localizados en cabeza, hocico, orejas, miembros torácicos y tronco. El diagnóstico de laboratorio se realiza por citología, histopatología y evidencia del agente causal; por PCR se demostró una secuencia novel Mycobacterium sp. En este trabajo se describen tres casos de SGLC confirmados por coloración de Ziehl Neelsen y citología. El tratamiento con rifampicina y claritromicina combinadas fue exitoso en el 100% de los casos. Precisar la identificación taxonómica del agente causal permitirá determinar los requerimientos de cultivo, facilitando la prevención, tratamiento y control de la enfermedad.

  16. Current thinking on genital herpes.

    Science.gov (United States)

    Hofstetter, Annika M; Rosenthal, Susan L; Stanberry, Lawrence R

    2014-02-01

    Genital herpes has a high global prevalence and burden of disease. This manuscript highlights recent advances in our understanding of genital herpes simplex virus (HSV) infections. Studies demonstrate a changing epidemiological landscape with an increasing proportion of genital herpes cases associated with HSV type 1. There is also growing evidence that the majority of infected individuals exhibit frequent, brief shedding episodes that are most often asymptomatic, which likely contribute to high HSV transmission rates. Given this finding as well as readily available serological assays, some have proposed that routine HSV screening be performed; however, this remains controversial and is not currently recommended. Host immune responses, particularly local CD4 and CD8 T cell activity, are crucial for HSV control and clearance following initial infection, during latency and after reactivation. Prior HSV immunity may also afford partial protection against HSV reinfection and disease. Although HSV vaccine trials have been disappointing to date and existing antiviral medications are limited, novel prophylactic and therapeutic modalities are currently in development. Although much remains unknown about genital herpes, improved knowledge of HSV epidemiology, pathogenesis and host immunity may help guide new strategies for disease prevention and control.

  17. prodromal herpes zoster mimicking odontalgia

    African Journals Online (AJOL)

    GB

    2013-03-01

    Mar 1, 2013 ... Mustafa MB, Arduino PG, Porter SR. Varicella zoster virus: review of its management. J Oral Pathol Med. 2009;38:673–88. 4. Millar EP, Troulis MJ. Herpes zoster of the trigeminal nerve: the dentists' role in diagnosis and treatment. J Can Dent Assoc. 1994;60:450–3. 5. Ragozziuo MW, Melton LJ, Kudand LT, ...

  18. Penatalaksanaan infeksi herpes simpleks oral rekuren Management of recurrent oral herpes simplex infection

    National Research Council Canada - National Science Library

    Erni Marlina; Bagus Soebadi

    2013-01-01

    .... The aim of this paper was to report and discuss management of recurrent oral herpes simplex infection which complicated in the diagnosis due to manifestation of both herpes labialis and intraoral...

  19. Penatalaksanaan infeksi herpes simpleks oral rekuren Management of recurrent oral herpes simplex infection

    OpenAIRE

    Erni Marlina; Bagus Soebadi

    2013-01-01

    Recurrent oral herpes simplex infection was the secondary or recurrent form of primary herpes simpex infection. In human, herpes simplex virus was latent or dormant and could reactivate. Recurrency due to virus reactivation induced by emotional stress, high fever, ultraviolet exposed, oral tissue or neuron tissue trauma, immunosuppresion condition, and hormonal disturbance. The aim of this paper was to report and discuss management of recurrent oral herpes simplex infection which ...

  20. Optimal management of genital herpes: current perspectives.

    Science.gov (United States)

    Sauerbrei, Andreas

    2016-01-01

    As one of the most common sexually transmitted diseases, genital herpes is a global medical problem with significant physical and psychological morbidity. Genital herpes is caused by herpes simplex virus type 1 or type 2 and can manifest as primary and/or recurrent infection. This manuscript provides an overview about the fundamental knowledge on the virus, its epidemiology, and infection. Furthermore, the current possibilities of antiviral therapeutic interventions and laboratory diagnosis of genital herpes as well as the present situation and perspectives for the treatment by novel antivirals and prevention of disease by vaccination are presented. Since the medical management of patients with genital herpes simplex virus infection is often unsatisfactory, this review aims at all physicians and health professionals who are involved in the care of patients with genital herpes. The information provided would help to improve the counseling of affected patients and to optimize the diagnosis, treatment, and prevention of this particular disease.

  1. Herpes Genitalis: Diagnosis, Treatment and Prevention

    OpenAIRE

    Sauerbrei, A.

    2016-01-01

    Herpes genitalis is caused by the herpes simplex virus type 1 or type 2 and can manifest as primary or recurrent infection. It is one of the most common sexually transmitted infections and due to associated physical and psychological morbidity it constitutes a considerable, often underestimated medical problem. In addition to providing the reader with basic knowledge of the pathogen and clinical presentation of herpes genitalis, this review article discusses important aspects of the laborator...

  2. Recent advances in management of genital herpes.

    OpenAIRE

    Tétrault, I.; Boivin, G.

    2000-01-01

    OBJECTIVE: To provide an update on new diagnostic tests and antiviral strategies for managing genital herpes. QUALITY OF EVIDENCE: Treatment guidelines are based on randomized clinical trials and recommendations from the Expert Working Group on Canadian Guidelines for Sexually Transmitted Diseases. Recommendations concerning other aspects of managing genital herpes (e.g., indications for using type-specific serologic tests) are mainly based on expert opinion. MAIN MESSAGE: Genital herpes is o...

  3. No. 207-Genital Herpes: Gynaecological Aspects.

    Science.gov (United States)

    Money, Deborah; Steben, Marc

    2017-07-01

    The purpose of this guideline is to provide recommendations to gynaecology health care providers on optimal management of genital herpes. More effective prevention of complications and transmission of genital herpes. Medline was searched for articles published in French and English related to genital herpes and gynaecology. Additional articles were identified through the references of these articles. All study types and recommendation reports were reviewed. Copyright © 2017. Published by Elsevier Inc.

  4. Valoración periodontal de caninos incluidos en situación vestibular a los tres años del tratamiento orotodóncico-quirúrgico

    OpenAIRE

    Alaejos, E. (Enrique); Rosa Gay, María Cristina de la; Berini Aytés, Leonardo; Gay Escoda, Cosme

    1999-01-01

    Para demostrar que los parámetros periodontales no se alteran por la fenestración con colgajo de reposición apical de los caninos incluidos, se seleccionaron 12 pacientes con canino incluido por vestibular y el canino contralateral correctamente erupcionado. El tratamiento fue ortodóncico-quirúrgico, con colgajo de reposición apical (9 casos) o de reposición apical lateral (3 casos). Tres años después de finalizar el tratamiento ortodóncico, se valoró el estado periodontal de los caninos medi...

  5. Herpes simplex virus following stab phlebectomy.

    Science.gov (United States)

    Hicks, Caitlin W; Lum, Ying Wei; Heller, Jennifer A

    2017-03-01

    Herpes simplex virus infection following surgery is an unusual postoperative phenomenon. Many mechanisms have been suggested, with the most likely explanation related to latent virus reactivation due to a proinflammatory response in the setting of local trauma. Here, we present a case of herpes simplex virus reactivation in an immunocompetent female following a conventional right lower extremity stab phlebectomy. Salient clinical and physical examination findings are described, and management strategies for herpes simplex virus reactivation are outlined. This is the first known case report of herpes simplex virus reactivation following lower extremity phlebectomy.

  6. Variations in herpes zoster manifestation

    Directory of Open Access Journals (Sweden)

    Uwe Wollina

    2017-01-01

    Full Text Available Herpes zoster (HZ is a neurocutaneous disorder due to endogenous reactivation of the varicella-zoster virus (VZV. The typical clinical manifestation is an acute segmental eruption of herpetiform umbilicated vesicles associated with malaise, pain, dysaesthesia, allodynia and probably fever. This review focuses on other possible clinical manifestations of the disease to sensitize physicians not to overlook HZ since only an early antiviral treatment can reduce the risk of post-zosteric neuralgia.

  7. CT of neonatal herpes encephalitis.

    Science.gov (United States)

    Herman, T E; Cleveland, R H; Kushner, D C; Taveras, J M

    1985-01-01

    Seven neonates with proven herpes (HSV type 2) encephalitis exhibited a characteristic sequence of findings on cranial computed tomography (CT). The initial CT abnormalities in all infants were fingerlike areas of cortical increased attenuation noted on unenhanced scans obtained 2-30 days after presentation. These usually were accentuated by increased white-matter lucency. Subsequently (more than 30 days after presentation), extensive cerebral destruction, multicystic encephalomalacia, and calcification were seen on follow-up CT scans obtained in five infants.

  8. Polyneuritis cranialis following herpes zoster

    Directory of Open Access Journals (Sweden)

    Radhakrishna H

    2000-01-01

    Full Text Available Herpes zoster is a common clinical condition involving cranial nerves. We encountered 3 cases in which multiple cranial nerves were involved besides the commoner ones. All the three cases were treated with acyclovir and oral steroids. Recovery of motor function was only partial in all three cases when reviewed 2 months after discharge. The clinical details and a brief review of literature are presented.

  9. In vitro characterization of gE negative bovine herpesvirus types 1.1 (BHV-1.1 and 1.2a (BHV-1.2a Caracterização in vitro de herpes vírus bovino tipos 1.1 (BHV-1.1 e 1.2a (BHV-1.2a gE negativos

    Directory of Open Access Journals (Sweden)

    Fernando R. Spilki

    2004-09-01

    Full Text Available This study aimed the in vitro growth characterization of a previously constructed Brazilian bovine herpesvirus 1.2a with a deletion in the glycoprotein E gene (BHV-1.2a gE-. The plaque sizes, penetration and growth kinetics of the Brazilian BHV-1.2a gE- were studied and compared with the parental virus, as well as with a BHV-1.1 gE- recombinant derived from an European BHV-1.1 strain. No statistical differences were observed between the gE- recombinants and the respective parental viruses penetration assays were performed. When single step growth curves were studied, no statistical differences were observed between gE- and parental viruses. However, it was observed that both gE- viruses were excreted from cells in significantly higher titres at 11 hours post infection in comparison with parental viruses. No statistical differences were observed when plaque sizes of parental viruses or gE- viruses we analyzed separately in each cell type. However, both gE- recombinants displayed a significantly reduced plaque areas on three different cell cultures, in comparison with parental viruses, indicating that the lack of gE had the same effect on both BHV-1 subtypes, manifested by a restricted cell-to-cell spread in infected cells.O presente estudo teve como objetivo a caracterização das propriedades de crescimento in vitro de uma amostra brasileira de herpesvírus bovino tipo 1.2a que apresenta uma deleção no gene que codifica a glicoproteína E (BHV-1.2a gE-. Os tamanhos de placa, cinética de penetração e cinética de multiplicação do vírus BHV-1.2a gE- foram estudados e comparados com o vírus parental, bem como com um vírus BHV-1.1 gE- recombinante, o qual é derivado de uma amostra européia de BHV-1.1. Em termos de cinética de penetração, não foram observadas diferenças significativas quando comparados os vírus gE- com os parentais. A determinação da cinética de multiplicação não demonstrou diferenças significativas entre os

  10. Melanoma en cavidad oral de un canino, reporte de un caso.

    Directory of Open Access Journals (Sweden)

    Vidales Torres

    2006-10-01

    Full Text Available Al laboratorio de Patología de Medicina Veterinaria ingresó para necropsia el cadáver de un canino macho de 11 años de edad de raza Dachshund. En la evaluación se encontró una masa en la cavidad oral que presentó dos coloración es que variaban de blanco a café. Para histopatología, se tomaron muestras de la masa en cavidad oral, ganglios linfáticos regionales, pulmón, corazón e hígado preservadas en formal de hído al 10%, luego de esta valoración se concluyó que la neoplasia en cavidad oral correspondía a un melanoma con características melánicas y amelánicas.

  11. Potencial antiviral da quercetina sobre o parvovírus canino

    Directory of Open Access Journals (Sweden)

    O.V. Carvalho

    2013-04-01

    Full Text Available Avaliou-se o efeito do flavonoide quercetina na replicação do parvovírus canino in vitro por meio do ensaio de determinação da atividade virucida (ensaio 1, ensaio de determinação da atividade sobre a célula (ensaio 2 e ensaio de tempo de adição das drogas em diferentes etapas do ciclo replicativo viral (ensaio 3. A quercetina apresentou significante atividade antiviral, com valores máximos de redução do título viral de 96,3% no ensaio 1, 90% no ensaio 2 e 90% no ensaio 3. Os efeitos mais expressivos ocorreram nas etapas de adsorção e penetração viral. Os resultados deste trabalho sugerem a importância da quercetina para a medicina veterinária.

  12. NEOPLASIAS TESTICULARES EN CANINOS: UN CASO DE TUMOR DE CÉLULAS DE SERTOLI

    Directory of Open Access Journals (Sweden)

    Pedro Eslava M

    2008-04-01

    Full Text Available Las neoplasias del testículo no son muy frecuentes en los animales domésticos Los caninos son los que las manifiestan con mayor frecuencia; estando entre los 0.7 y 4.6% de todos los tumores que sufren. Algunos factores se han asociado como predisponentes: entre ellos la edad madura y la presencia del criptorquidia uni o principalmente bilateral. Las neoplasias del testículo más frecuente son el tumor de células de Sertoli, el tumor de células de Leydig y los seminomas, que en general presentan la conducta benigna. El tratamiento recomendado previa evaluación clínica, es la orquiectomía (uni o bilateral, incluidos en los casos de criptorquidismo el testículo alojado en el escroto. En el presente manuscrito se realiza una revisión del tema en su primera parte; en la segunda, se describe el caso de un tumor de células del Sertoli en un canino Cocker que presentó al examen clínico un testículo retenido y síndrome feminizante. En este se caso se efectuó el diagnóstico histopatológico después de la extracción quirúrgica de la masa abdominal y también se realizó la extirpación del testículo alojado en el escroto.

  13. Ovário-histerectomia em caninos por cirurgia laparoscópica

    Directory of Open Access Journals (Sweden)

    Maurício Veloso Brun

    2000-12-01

    Full Text Available Neste estudo, foram realizadas ovário-histerectomias laparoscópicas em 24 caninos. Os procedimentos cirúrgicos foram realizados sob anestesia geral, com os animais em decúbito dorsal. A cavidade abdominal foi puncionada com a agulha de Veress e foi insuflada com CO2. Os animais foram então colocados em posição de Trendelenburg, e quatro trocartes foram introduzidos em diferentes regiões da parede abdominal. Após a identificação do útero, os vasos uterinos foram isolados e ligados com dois clipes de titânio. O corpo do útero foi seccionado cranialmente à cérvix. A bursa ovariana foi exposta, e o ligamento suspensor foi apreendido com uma pinça. Procedeu-se à aplicação de um clipe neste ligamento previamente a sua secção. O complexo arteriovenoso ovariano foi ligado com um clipe e depois foi seccionado em conjunto com o mesovário. O ligamento redondo e o mesométrio foram seccionados com tesoura e cauterização monopolar. O útero e ambos os ovários foram retirados em bloco da cavidade por uma das incisões existentes. A principal complicação transoperatória foi a ocorrência de hemorragia, que ocasionou um óbito e uma conversão para cirurgia aberta. Na maioria dos animais, esta complicação foi adequadamente controlada pela aplicação de clipes e/ou utilização de cauterização monopolar. A realização de ovário-histerectomia em caninos por cirurgia laparoscópica demonstrou ser viável, e a técnica descrita para este procedimento mostrou-se adequada.

  14. Prevalencia de helmintos intestinales en caninos del departamento del Quindío.

    Directory of Open Access Journals (Sweden)

    María Isabel Giraldo

    2005-09-01

    Full Text Available Introducción. Los helmintos intestinales son agentes patógenos que afectan animales domésticos y que a través de ellos pueden infectar humanos. Objetivo. El objetivo del trabajo fue determinar la prevalencia de helmintos intestinales en perros con dueño del departamento del Quindío. Materiales y métodos. Estudio descriptivo prospectivo. Se aplicó una encuesta epidemiológica a los propietarios de los perros. Se recolectaron muestras de heces de los caninos registrados en la jornada de vacunación antirrábica del 2003 en el departamento del Quindío. Las muestras de materia fecal frescas fueron analizadas utilizando la técnica de diagnóstico de Ritchie. Resultados. Se analizaron 324 muestras de heces caninas; el 67,6% de los perros eran de razas puras y el 32,4% razas mestizas. Se encontró una prevalencia del 22,2%; Ancylostoma caninum fue el parásito más frecuente, 13,9%. También se observó Trichuris vulpis, 4,3%; Toxocara canis, 2,5%, y Strongyloides stercoralis, 4,0%. El 2,46% de las mascotas se encontraron multiparasitadas. Conclusión. La frecuencia de helmintos intestinales en el departamento del Quindío fue de 22,2% y la presencia de estos parásitos coincide con factores como la edad y la permanencia del canino en la calle, entre otros. Por esta razón, es necesario establecer programas de vigilancia y prevención en la población humana y canina.

  15. Etiología de los caninos superiores impactados: una visión histórica

    Directory of Open Access Journals (Sweden)

    Diego Luis Arellano

    2012-09-01

    Full Text Available Los caninos maxilares impactados (CMI son una frecuente condición clínica, a pesar de la relativa baja prevalencia de impactación oral. Muchos estudios se han enfocado en la práctica terapéutica, que consta de un abordaje interdisciplinario que en muchas ocasiones implica varias especialidades, pero la evidencia disponible sobre su etiología ha sido diversa y escasa. A continuación se explora literatura disponible de antecedentes históricos que permiten explicar las diferentes teorías sobre la etiología de los caninos impactados. Así se resalta la importancia de realizar un diagnóstico temprano de dicha alteración para facilitar su manejo y reducir las secuelas.

  16. Recurrent facial urticaria following herpes simplex labialis

    Directory of Open Access Journals (Sweden)

    Vijay Zawar

    2012-01-01

    Full Text Available We describe recurrent acute right-sided facial urticaria associated with herpes labialis infection in a middle-aged female patient. Antiviral medications and antihistamines not only successfully cleared the herpes infection and urticaria but also prevented further recurrences.

  17. Psychosocial Treatment for Recurrent Genital Herpes.

    Science.gov (United States)

    Longo, David J.; And Others

    1988-01-01

    Assigned 21 individuals with recurrent genital herpes to psychosocial intervention, social support, or waiting-list control conditions. Those receiving psychosocial intervention (herpes simplex virus information, relaxation training, stress management instructions, and an imagery technique) reported significantly greater reductions in herpes…

  18. Experiential Interventions for Clients with Genital Herpes.

    Science.gov (United States)

    Cummings, Anne L.

    1999-01-01

    Explores potential benefits of incorporating concepts and interventions from experimental therapy to help clients with psychosocial difficulties in learning to live with genital herpes. Recommends experimental counseling of two-chair dialog, empty chair, and metaphor for helping clients with emotional sequelae of genital herpes. Presents case…

  19. SHORT COMMUNICATION Serological profiles of Herpes simplex ...

    African Journals Online (AJOL)

    Dr.Mirambo

    SHORT COMMUNICATION. Serological profiles of Herpes simplex ... Herpes Simplex Virus Type-2 (HSV-2) infections is one of the most common sexually transmitted infections (STIs) and causes ... A total of 174 non HIV infected health professional students were enrolled between April and May 2016 from Mwanza City, ...

  20. 21 CFR 866.3305 - Herpes simplex virus serological assays.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Herpes simplex virus serological assays. 866.3305... simplex virus serological assays. (a) Identification. Herpes simplex virus serological assays are devices... herpes simplex virus in serum. Additionally, some of the assays consist of herpes simplex virus antisera...

  1. MELLITUS TIPO 1

    Directory of Open Access Journals (Sweden)

    Luciana Vládia Carvalhêdo Fragoso

    2010-01-01

    Full Text Available Investigación de carácter cualitativo, con el objetivo de comprender las experiencias cotidianas de los adolescentes con diabetes tipo 1. Los sujetos del estudio son 14 adolescentes atendidos en una clínica para la diabetes en Fortaleza, Ceará, Brasil, de junio a octubre de 2008. La recolección de los datos se hizo a través de entrevistas semi-estructuradas y se organizaron de acuerdo al análisis de contenido de Morse y Field. Se observó que el descubrimiento de la diabetes fue un momento difícil para los adolescentes debido a los cambios que tuvieron que hacer como el control terapéutico. Hacer una dieta adecuada es muy difícil como consecuencia de estímulos internos y externos a que están sometidos y a las dificultades financieras. Los adolescentes tienen el apoyo de la familia y amigos para su tratamiento diario. Además, les gusta el servicio realizado por los profesionales de salud de la clínica. Sin embargo, hay mucho que mejorar como enfermeras en la valorización de las experiencias de la vida de los adolescentes con diabetes, como la identificación de factores que interfieren en el control metabólico.

  2. Gangliosidosis generalizada tipo 1

    Directory of Open Access Journals (Sweden)

    Iván Hernández García

    Full Text Available La gangliosidosis generalizada tipo 1 es una enfermedad de acúmulo lisosomal producida por mutaciones en el gen de la enzima b-galactosidasa, caracterizada fundamentalmente por toma del sistema nervioso central, la visceromegalia, disostosis ósea y dimorfismo facial. Se presenta el caso de un lactante varón, hijo de padres no consanguíneos, de 5 meses de edad, Apgar 6/8 debido a hipoxia neonatal, con historia de múltiples ingresos por enfermedad diarreica e infecciones respiratorias. Es remitido a la Consulta de Genética Clínica por retardo del desarrollo psicomotor, macrocráneo y hepatomegalia, además de máculas hipercrómicas en piel. En el examen físico se encontraron evidencias de una posible afectación por enfermedad metabólica lisosomal. Entre las enfermedades a descartar estaban la galactosialidosis, de características clínicas similares, y la enfermedad de Morquio, con diferente presentación clínica pero idéntico defecto enzimático.

  3. Herpes zoster - associated erythema multiforme.

    Science.gov (United States)

    Wollina, Uwe; Gemmeke, Astrid

    2009-04-05

    Erythema multiforme is a cutaneous reaction that has only rarely been described in varicella zoster virus infection. We describe a 76-year old immunocompetent male patient with thoracic herpes zoster. While treated with oral brivudin he developed a widespread cutaneous erythema multiforme. The lesions completely cleared with two weeks with systemic corticosteroids. Varicella zoster infections are possible triggers of erythema multiforme and this is the oldest patient reported with such an association. Brivudin itself has not been reported to induce erythema multiforme and is an unlikely cause of disease in our patient.

  4. Neonatal Herpes Simplex Virus Infection.

    Science.gov (United States)

    James, Scott H; Kimberlin, David W

    2015-09-01

    Herpes simplex virus (HSV) 1 and HSV-2 infections are highly prevalent worldwide and are characterized by establishing lifelong infection with periods of latency interspersed with periodic episodes of reactivation. Acquisition of HSV by an infant during the peripartum or postpartum period results in neonatal HSV disease, a rare but significant infection that can be associated with severe morbidity and mortality, especially if there is dissemination or central nervous system involvement. Diagnostic and therapeutic advances have led to improvements in mortality and, to a lesser extent, neurodevelopmental outcomes, but room exists for further improvement. Copyright © 2015 Elsevier Inc. All rights reserved.

  5. Primary Genital Herpes Diseases in İnfancy

    Directory of Open Access Journals (Sweden)

    Sevinç Gümüş Pekacar

    2016-09-01

    Full Text Available Symptomatic primary genital herpes infection is very rare in early childhood. Herpes simplex virus 1 type is the infectious agent in 20-50% percent of primery infections. Sexual abuse should be considered when genital herpes is seen in a person before sexual active age. It is mild and self limiting unless the patient is immune compramised. In this paper we discussed a 17 months old patient with genital herpes and approach to genital herpes in children.

  6. mellitus tipo 2

    Directory of Open Access Journals (Sweden)

    Margarita Lazcano-Ortiz

    2008-01-01

    Full Text Available Objetivo: valorar las propiedades psicométricas de la escala de afrontamiento y proceso de adaptación de Roy en población mexicana. Materiales y métodos: la escala se aplicó a 200 participantes con diabetes mellitus tipo 2. Para validar el constructo se realizó la extracción de factores con componentes principales y rotación Varimax, con Eigenvalores por arriba de 1 y cargas de factor mayores a ,30. Resultados: seis reactivos fueron eliminados del análisis por mostrar correlación negativa con la correlación total de la escala. El análisis de componentes principales inicial reveló nueve factores con una variación explicada de 65,29%. Sin embargo, no se consideraron tres factores por contener cada uno de ellos solamente un reactivo. Por tanto, la escala final se acepta con 38 reactivos. El coeficiente de confiabilidad Alfa de Cronbach fue de, 93. Discusión: el análisis reveló seis factores, uno más de lo reportado por Roy, y con mayor variación explicada. Algunos reactivos parecen no ser bien comprendidos por los participantes. Conclusiones: este artículo aporta una aproximación metodológica para explorar la adecuación de un instrumento a una población diferente para la que originalmente fue diseñado. Se concluye que la escala tiene consistencia interna y validez de constructo incipiente, los datos reportados en este estudio deben tomarse en cuenta con cautela. Es conveniente revisar de nuevo los reactivos y adecuarlos a la cultura particular, y probar la escala de nuevo con pacientes con enfermedades crónicas degenerativas a fin de contar con instrumentos culturalmente equivalentes.

  7. The genital herpes problem in pregnancy.

    Science.gov (United States)

    Guerra, B; Puccetti, C; Cervi, F

    2012-10-01

    Genital herpes is a common sexually transmitted infection. In reproductive age it involves the additional risk of vertical transmission to the neonate. Rates of transmission are affected by the viral type and whether the infection around delivery is primary or recurrent. Neonatal herpes is a rare but very severe complication of genital herpes infection and is caused by contact with infected genital secretions at the time of labor. Maternal acquisition of herpes simplex virus (HSV) in the third trimester of pregnancy carries the highest risk of neonatal transmission. Prevention of neonatal herpes depends on preventing acquisition of genital HSV infection during late pregnancy and avoiding exposure of the infant to herpetic lesions during delivery. Uninfected woman should be counselled about the need of avoiding sexual contact during the third trimester. Elective caesarean section before the onset of labor is the choice mode of delivery for women with genital lesions or with prodromal symptoms near the term, even if it offers only a partial protection against neonatal infection. Antiviral suppressive therapy is used from 36 weeks of gestation until delivery in pregnant women with recurrences to prevent genital lesions at the time of labor so reducing the need of caesarean sections. Currently, routine maternal serologic screening is not yet recommended. Because most mothers of infants who acquire neonatal herpes lack histories of clinically evident genital herpes, researchers should focus on the recognition of asymptomatic primary genital HSV infections.

  8. MAST CELL TUMOR IN DOGS: RETROSPECTIVE STUDY MASTOCITOMA CANINO: ESTUDO RETROSPECTIVO

    Directory of Open Access Journals (Sweden)

    Duvaldo Eurides

    2008-04-01

    Full Text Available This retrospective study included 49 dogs, 28 males and 21 females, of several breeds, between two and 17 years old. The majority of dogs were mixed breed or Boxers and Teckels, six to nine years old. Eleven animals showed grade I mast cell tumor, 10 grade II and nine grade III. Surgery alone or associated with chemotherapy were performed in the most of cases. The results from our study indicate that surgery alone promotes the highest survival time because surgery procedure is indicated in cases with better prognosis. Teckels and Boxers show highest survival time. Dogs with multiple lesions have lowest survival time. The histologic grades of mast cell tumors have similar incidence, however the incidence tends to decrease from grade I to III. High-grade tumors promote lowest survival time. Fine needle aspiration cytology allow accurate diagnosis of canine mast cell tumors, although the histopathology is required to determine the histologic grade allowing an adequate treatment and so a highest survival time. Both incomplete chemotherapy and untreated groups have poor prognosis. In the most of cases the survival time is low. Este estudo retrospectivo incluiu um total de 49 cães, 28 machos e 21 fêmeas, de diversas raças, entre dois e 17 anos de idade. A maioria dos cães acometidos era mestiça ou da raça Boxer e Teckel, apresentavam idade entre seis e nove anos. Onze animais apresentaram mastocitoma grau I, 10 grau II e nove grau III. Na maioria dos casos, empreitou-se apenas a intervenção cirúrgica ou esta associada à quimioterapia. Conclui-se que a intervenção cirúrgica isolada, utilizada em casos de prognóstico favorável, proporciona maior sobrevida. Cães das raças Teckel e Boxer apresentam sobrevida maior. Cães acometidos em múltiplas regiões do corpo apresentam menor sobrevida. A incidência dos graus histológicos do mastocitoma canino se dá de forma semelhante, porém tende a decrescer do grau I ao III. Mastocitomas de

  9. Pênfigo foliáceo canino: estudo retrospectivo de 43 casos clínicos e terapia (2000-2005 Canine Pemphigus foliaceus: a retrospective study of 43 clinical cases and therapy (2000-2005

    Directory of Open Access Journals (Sweden)

    Ana C. Balda

    2008-08-01

    Full Text Available No período de agosto de 2000 a julho de 2005 foram atendidos 43 casos de Pênfigo Foliáceo (PF canino no Serviço de Dermatologia do Hospital Veterinária, Universidade de São Paulo. Com este estudo retrospectivo visou-se atualizar dados referentes à caracterização sexual, definição racial e raça, idade, tipo e topografia lesional, quadro sintomático e resposta aos tratamentos isolados com prednisona e com a associação desta à azatioprina, além de demonstrar o aumento na ocorrência do PF relativamente à série histórica pretérita (1986-2000 do mesmo Serviço.From August 2000 to July 2005 were attended 43 cases of canine Pemphigus foliaceous (PF by the Dermatology Service of the Veterinary Teaching Hospital, University of São Paulo. The aim of the present study was to update the records referred to sex, breed, age, type and location of the lesions, clinical signs, and response to treatments with prednisone or combination with prednisone and azathioprine, and also to demonstrate the increase of occurrence of PF compared with the former series (1986-2000 observed in the same Service.

  10. EMPLEO DEL MÉTODO BIOALBERIC EN EL TRATAMIENTO DE LA DIABETES MELLITUS EN CANINOS DOMÉSTICOS / Use of BioAlberic method for treating diabetes mellitus in domestic dogs

    Directory of Open Access Journals (Sweden)

    Yailyn Ramos Morejón

    2013-04-01

    Full Text Available Resumen: La diabetes mellitus es una enfermedad frecuente en los caninos domésticos, en la cual pueden presentarse alteraciones del sistema cardiovascular, difíciles de tratar. Una de las vías alternativas de tratamiento en este tipo de animales pudiera ser el empleo del método BioAlberic. En este artículo se presentan los resultados obtenidos en la aplicación de este método (con el producto Rapsul al iniciar el tratamiento de la diabetes mellitus en dos perros domésticos, como parte del proceso de investigación de nuestro grupo para desarrollar los productos BioAlberic y evaluar su efectividad. / Abstract: Diabetes mellitus is a common disease in domestic dogs, in which cardiovascular system disorders may occur, and these are difficult to treat. One of the alternative ways of treatment in these animals could be the use of BioAlberic method. This article presents the results of the application of this method (with the Rapsul product at the beginning of treatment of diabetes mellitus in two domestic dogs, as part of the research process of our group to develop BioAlberic products and evaluate their effectiveness.

  11. Evaluación del hemograma en caninos sanos sometidos a la administracion de cisplatina

    Directory of Open Access Journals (Sweden)

    Carlos Calpa O

    2010-08-01

    Full Text Available Objetivo. Evaluar los valores medios del hemograma en perros sanos durante la quimioterapia con cisplatina. Materiales y métodos. Se evaluaron los parámetros del hemograma de ocho caninos sanos sometidos a terapia con cisplatina, distribuidos en dos grupos. A los perros del grupo uno se les administró cisplatina (70 mg/m², i.v. y para prevenir la nefrotoxicidad recibieron suero fisiológico al 0.9% (25mL/kg/h, i.v.. Los animales del grupo dos no recibieron cisplatina. Resultados. El hemograma de los perros del grupo uno no mostró diferencia significativa (p>0.05 con respecto al de los animales del grupo dos. Conclusiones. Los datos obtenidos indicaron que el protocolo con cisplastina no alteró significativamente los valores medios del hemograma y el número de sesiones de quimioterapia aumenta el riesgo de disminución de los valores del hemograma.

  12. Herpes Simplex Virus-1 and Bell's Palsy

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2008-05-01

    Full Text Available The association between herpes simplex virus-1 (HSV-1 infection and Bell palsy was determined in 47 children studied at Children's Hospital at Montefiore, Bronx, NY. Swabs of saliva and conjunctiva were taken for PCR testing.

  13. Managing herpes zoster and postherpetic neuralgia

    National Research Council Canada - National Science Library

    Galluzzi, Katherine E

    2009-01-01

    Treatment strategies for herpes zoster infection include limiting viral replication with anti-infective agents as well as limiting associated acute and chronic neuropathic pain with a variety of analgesics...

  14. Generating protective immunity against genital herpes.

    Science.gov (United States)

    Shin, Haina; Iwasaki, Akiko

    2013-10-01

    Genital herpes is an incurable, chronic disease that affects millions of people worldwide. Not only does genital herpes cause painful, recurrent symptoms, it is also a significant risk factor for the acquisition of other sexually transmitted infections such as HIV-1. Antiviral drugs are used to treat herpes simplex virus (HSV) infection, but they cannot stop viral shedding and transmission. Thus, developing a vaccine that can prevent or clear infection will be crucial in limiting the spread of disease. In this review we outline recent studies that improve our understanding of host responses against HSV infection, discuss past clinical vaccine trials, and highlight new strategies for vaccine design against genital herpes. Copyright © 2013 Elsevier Ltd. All rights reserved.

  15. Herpes zoster - typical and atypical presentations.

    Science.gov (United States)

    Dayan, Roy Rafael; Peleg, Roni

    2017-08-01

    Varicella- zoster virus infection is an intriguing medical entity that involves many medical specialties including infectious diseases, immunology, dermatology, and neurology. It can affect patients from early childhood to old age. Its treatment requires expertise in pain management and psychological support. While varicella is caused by acute viremia, herpes zoster occurs after the dormant viral infection, involving the cranial nerve or sensory root ganglia, is re-activated and spreads orthodromically from the ganglion, via the sensory nerve root, to the innervated target tissue (skin, cornea, auditory canal, etc.). Typically, a single dermatome is involved, although two or three adjacent dermatomes may be affected. The lesions usually do not cross the midline. Herpes zoster can also present with unique or atypical clinical manifestations, such as glioma, zoster sine herpete and bilateral herpes zoster, which can be a challenging diagnosis even for experienced physicians. We discuss the epidemiology, pathophysiology, diagnosis and management of Herpes Zoster, typical and atypical presentations.

  16. Herpes Genitalis: Diagnosis, Treatment and Prevention

    Science.gov (United States)

    Sauerbrei, A.

    2016-01-01

    Herpes genitalis is caused by the herpes simplex virus type 1 or type 2 and can manifest as primary or recurrent infection. It is one of the most common sexually transmitted infections and due to associated physical and psychological morbidity it constitutes a considerable, often underestimated medical problem. In addition to providing the reader with basic knowledge of the pathogen and clinical presentation of herpes genitalis, this review article discusses important aspects of the laboratory diagnostics, antiviral therapy and prophylaxis. The article is aimed at all health-care workers managing patients with herpes genitalis and attempts to improve the often suboptimal counselling, targeted use of laboratory diagnostics, treatment and preventive measures provided to patients. PMID:28017972

  17. Tratamiento ortodóntico quirúrgico de canino maxilar impactado con reabsorción radicular bilateral: Reporte de caso

    OpenAIRE

    Mercado-Mamani, Sively; Universidad Católica Santa María. Arequipa.; Ríos-Villasis, Katty; Universidad Inca Garcilazo de la Vega. Lima.

    2014-01-01

    Los dientes caninos superiores permanentes impactados bilaterales son un problema clínico que puede provocar una serie de secuelas irreversibles como la reabsorción radicular de dientes vecinos. Se describe el caso de una paciente con ausencia clínica de caninos superiores que se encontraban impactados orientados hacia vestibular  produciendo reabsorción de los dos tercios de la raíces de todos los incisivosSuperiores,los que fueron extraídos, en el mismo acto se realizó la exposición quirúrg...

  18. MANEJO TERAPÉUTICO DE LA INTOXICACIÓN CON FLUORACETATO DE SODIO (GUAYAQUIL®) EN CANINOS: REPORTE DE CINCO CASOS –2012-2013–

    OpenAIRE

    Molina, V.M.

    2014-01-01

    El presente reporte relata el manejo terapéutico de la intoxicación con fluoracetato de sodio dispensado a cinco caninos en la Clínica Veterinaria de Antioquia, Medellín (Co-lombia), entre los años 2012 y 2013. Cinco pacientes caninos llegaron a consulta con cuadro neurológico, disforia y convulsiones, con una hora de evolución. Los animales entraron en contacto con el fluoracetato de sodio (rodenticida Guayaquil®) por vía oral. Los pacientes fueron sometidos a un protocolo de manejo que incl...

  19. Variaciones e índice simétrico de las variables cinéticas de caninos normales en el trote

    OpenAIRE

    Sergio Andrés Arias Serrato; Cleuza Maria de Faria Rezende; Hans Joachim Menzel; João Vicente Doretto; Plinio Ferreira Mantovani; Letícia Goulart de Oliveira; Jair Pérez Osório; Piedad Cristina Rivas López; Iván Darío Álvarez Ramírez

    2012-01-01

    Los índices de simetría en la marcha de caninos han sido escasamente reportados. Falta consenso y se desconoce el efecto de la normalización en los resultados, sobre todo en la ortogonal craneocaudal. La cinética de la marcha en el ciclo de trote de quince perros mestizos se analizó mediante una plataforma de fuerza amplificada buscando determinar la simetría en la marcha. Se determinó el índice de simetría (IS) bajo dos sistemas de normalización de los datos en caninos entonces: normalizació...

  20. Presencia de anomalías dentomaxilofaciales en niños con pérdida prematura de caninos temporales

    OpenAIRE

    Amarelys Morera Pérez; Yuneis Ríos Paz; Diana M Villa Fernández; Arletys Cobas

    2016-01-01

    Fundamento: Los caninos temporales, por ser de los últimos en hacer el recambio a permanentes, son de gran importancia en el mantenimiento del espacio en el arco y la adecuada oclusión. Su pérdida prematura tiene mayor repercusión sobre el sector anterior, aunque también puede afectar el sector posterior.Objetivo: describir la presencia de anomalías dentomaxilofaciales en niños con pérdida prematura de caninos temporales.Métodos: se realizó un estudio descriptivo, transversal, en niños de 5 a...

  1. Herpes zoster oticus: diagnosis and management.

    Science.gov (United States)

    Muecke, M; Amedee, R G

    1993-08-01

    Herpes zoster oticus (Ramsay Hunt syndrome) is recognized as a polycranial neuritis caused by the DNA virus Herpes zoster and characterized by damage to sensory and motor nerves, including the audio-vestibular apparatus. Common presenting symptoms include cutaneous auricular vesicles, severe otalgia, inflammation of the pinna, and occasionally unilateral sudden facial paralysis. This article reviews the medical management of this disease, including the efficacy of antibiotics, corticosteroids, and acyclovir, along with the role of surgical decompression of the facial nerve.

  2. Genital Herpes in Marital Partners

    Directory of Open Access Journals (Sweden)

    Mary Jacob

    1988-01-01

    Full Text Available During 1983-86, 225 patients were clinically diagnosed to have genital herpes (GH at our clinic. Of these, 90 men and 55 women were currently married. All the spouses were screened clinically and through standardized techniques for isolation and typing of herpes simplex virus, serological testing and Papanicolaou smear. There were 90 couples in whom at least one spouse had GH and in 38 (42% couples both partners had GH. Clinically, 49% of wives and 75% of husbands of GH patients were diagnosed to have the disease. The spouses of recurrent GH patients had a higher frequency of the disease than spouses of primary GH patients. Among spouses who were clinically asymptomatic, 40% had high serological titres suggestive of GH. Wives generally experienced more severe symptoms, especially pain in the lesions. Majority of lesions in both the partners were vesicles and ulcers. Prodromata were more among recurrent GH patients in both the partners. The frequency of recurrences wasalso similar in spouses. Seventy percent of wives and 40% of husbands could not identify any precipitating factor. Intercourse, physical stress and rich food were cited as possible factors in the remaining. All the wives had acquired the diseases through their husbands who were promiscuous. Fifty percent of husbands had been infected before marriage. Given the fact that asymptomatic carriers exist, it is better to consider all marital partners of GH as infected. Repeated and long-term follow, - up examination, particularly of wives of GH patients is therefore essential as an important socio-preventive aspect of this disease.

  3. Recent advances in management of genital herpes.

    Science.gov (United States)

    Tétrault, I.; Boivin, G.

    2000-01-01

    OBJECTIVE: To provide an update on new diagnostic tests and antiviral strategies for managing genital herpes. QUALITY OF EVIDENCE: Treatment guidelines are based on randomized clinical trials and recommendations from the Expert Working Group on Canadian Guidelines for Sexually Transmitted Diseases. Recommendations concerning other aspects of managing genital herpes (e.g., indications for using type-specific serologic tests) are mainly based on expert opinion. MAIN MESSAGE: Genital herpes is one of the most common sexually transmitted diseases, affecting about 20% of sexually active people; up to 80% of cases are undiagnosed. Because of frequent atypical presentation and the emotional burden associated with genital herpes, clinical diagnosis should be confirmed by viral culture. Type-specific serologic assays are now available, but their use is often restricted to special situations and requires adequate counseling. New antivirals (valacyclovir and famciclovir) with improved pharmacokinetic profiles have now been approved for episodic treatment of recurrences and suppressive therapy. CONCLUSION: Wise use of new diagnostic assays for herpes simplex coupled with more convenient treatment regimens should provide better management of patients with genital herpes. Images Figure 1 PMID:10955181

  4. Herpes

    Science.gov (United States)

    ... Factor Antibody Iron Iron Tests JAK2 Mutation Kidney Stone Analysis Kidney Stone Risk Panel KRAS Mutation Lactate Lactate Dehydrogenase (LD) ... open lesions. HSV-1 primarily causes blisters or "cold sores" around the mouth, while HSV-2 usually ...

  5. The maspin expression in canine mammary tumors: an immunohistochemical and molecular study A expressão do maspin nos tumores mamários caninos: um estudo imuno-histoquímico e molecular

    Directory of Open Access Journals (Sweden)

    Debora A.P.C. Zuccari

    2009-02-01

    Full Text Available The serpin maspin, a tumor suppressor in breast cancer was described as an inhibitor of cell migration and inducer of cell adhesion between the basement membrane and extracellular matrix resulting in inhibition of tumor metastasis. In contrast, overexpression of maspin is correlated with poor prognosis in other types of cancer. Little is known about expression, regulation and function of maspin in canine mammary tumors. It was demonstrated in this study, a loss of maspin expression in malignant canine mammary cells compared with a pool of normal canine mammary tissue, analyzed by quantitative real-time PCR; weak maspin expression in malignant canine mammary tumors were observed by immunohistochemistry. It was also demonstrated that a correlation with nuclear maspin expression and a good prognosis. It is suggested that maspin could be used as a prognostic marker in canine mammary neoplasia.O serpin maspin, um supressor tumoral no câncer de mama foi descrito como inibidor de migração celular e indutor de adesão celular entre a membrana basal e a matriz extracelular resultando na inibição da metástase tumoral. Por outro lado, a alta expressão do maspin está relacionada com um mau prognóstico em outros tipos de câncer. Pouco se sabe sobre a expressão, regulação e função do maspin nos tumores mamários caninos. Neste estudo, foi demonstrada uma perda da expressão de maspin nas células mamárias malignas de cães quando comparadas com um pool de tecido mamário normal de cães, analisado por PCR quantitativa em tempo real. Houve uma expressão fraca maspin em preparações de tumores mamários malignos observadas por imuno-histoquímica. Também foi verificado que a expressão nuclear do maspin em tumores mamários caninos está relacionada a um bom prognóstico. Assim, o maspin pode ser utilizado como um marcador prognóstico nas neoplasias mamárias em cães.

  6. Base de datos de medidas electrocardiográficas para caninos residentes en la ciudad de Bogotá

    OpenAIRE

    Mauricio Ortega Tamayo; Edwin Andrés Cerquera; Rafael Gutiérrez Salamanca

    2006-01-01

    El siguiente trabajo presenta la base de datos Vetuan I, que contiene las medidas electrocardiográficas de 100 pacientes caninos sin anomalías cardíacas examinados en la Clínica Veterinaria Veteriland de la ciudad de Bogotá, y atendidos por personal de la Facultad de Medicina Veterinaria de la Universidad Antonio Nariño, Bogotá. Las medidas que se incluyen dentro de la base de datos, comprenden la duración y amplitud de de las ondas que componen un ciclo cardíaco en cada uno de los registros ...

  7. Função canino desempenhada pelo pré-molar Canine function performed by the premolar

    Directory of Open Access Journals (Sweden)

    Omar Gabriel da Silva Filho

    2006-06-01

    Full Text Available A extração do canino permanente suscita indignação de muitos ortodontistas ortodoxos cuja opinião oscila da ambivalência à condenação radical, devido principalmente à crença do perverso déficit funcional resultante, mas também atrelada à preocupação do efeito estético no sorriso. Essa última, sim, preocupação maior do leigo, que vê a Ortodontia principalmente como um exercício estético. Sem trair as convicções certamente legítimas, os objetivos oclusais de um tratamento ortodôntico visam conciliar estética, função e saúde periodontal, com ou sem caninos. O presente artigo ilustra a possibilidade de trocar o canino pelo primeiro pré-molar num tratamento ortodôntico conduzido com extração de dentes. Essa situação, que enfrenta resistência por parte de ambos, ortodontistas e pacientes, elimina o dente canino sem, no entanto, eliminar a função da cúspide canina na desoclusão lateral, isolada ou em grupo, o que sela harmonia com os conceitos funcionais da escola gnatológica.Extraction of the permanent canine surprises many traditional orthodontists who believe that negative functional and unaesthetic results may arise from the procedure. Although esthetics is the major concern of layperson people, the occlusal aims of the orthodontic treatment are esthetics, occlusal function and periodontal health, with or without canines. The current paper describes the possibility of extracting the canine instead of the premolar in an orthodontic treatment with teeth extraction. In such a situation, which is not easily accepted by orthodontists and patients, the canine is eliminated but not its cusp function in lateral mandibular movements, thus maintaining the gnathologic functional concepts.

  8. Degeneración corneal en un canino como único signo de hipotiroidismo, descripción de un caso

    OpenAIRE

    Meana, María de los Ángeles; Cassagne, P. N.; Zapata, Gustavo L.

    2011-01-01

    Los depósitos corneales pueden ser causa de lesiones crónicas locales o enfermedades sistémicas. Esta alteración en la transparencia corneal se denomina degeneración corneal y ocurre como consecuencia del depósito de lípidos, calcio o su combinación. Los autores reportan un caso de degeneración corneal bilateral en un canino macho de 4 años asociado a una presentación atípica de hipotiroidismo. Donde se demuestra el diagnóstico y su posterior respuesta al tratamiento.

  9. CBO-richtlijn 'Seksueel overdraagbare aandoeningen en herpes neonatorum' (herziening)

    NARCIS (Netherlands)

    Bleker, O. P.; van der Meijden, W. I.; Wittenberg, J.; van Bergen, J. E. A. M.; Boeke, A. J. P.; van Doornum, G. J. J.; Henquet, C. J. M.; Galama, J. M. D.; Postma, M. J.; Prins, J. M.; van Voorst Vader, P. C.

    2003-01-01

    The Dutch Institute for Health Care Improvement revised guideline, 'Sexually transmitted diseases and neonatal herpes' summarises the current scientific position on the diagnosis and treatment of a great number of sexually transmitted diseases (STD) and neonatal herpes. Symptomatic treatment of

  10. Prodrugs of herpes simplex thymidine kinase inhibitors.

    Science.gov (United States)

    Yanachkova, Milka; Xu, Wei-Chu; Dvoskin, Sofya; Dix, Edward J; Yanachkov, Ivan B; Focher, Federico; Savi, Lida; Sanchez, M Dulfary; Foster, Timothy P; Wright, George E

    2015-04-01

    Because guanine-based herpes simplex virus thymidine kinase inhibitors are not orally available, we synthesized various 6-deoxy prodrugs of these compounds and evaluated them with regard to solubility in water, oral bioavailability, and efficacy to prevent herpes simplex virus-1 reactivation from latency in a mouse model. Organic synthesis was used to prepare compounds, High Performance Liquid Chromatography (HPLC) to analyze hydrolytic conversion, Mass Spectrometry (MS) to measure oral bioavailability, and mouse latent infection and induced reactivation to evaluate the efficacy of a specific prodrug. Aqueous solubilities of prodrugs were improved, oxidation of prodrugs by animal cytosols occurred in vitro, and oral absorption of the optimal prodrug sacrovir™ (6-deoxy-mCF3PG) in the presence of the aqueous adjuvant Soluplus® and conversion to active compound N(2)-[3-(trifluoromethyl)pheny])guanine (mCF3PG) were accomplished in mice. Treatment of herpes simplex virus-1 latent mice with sacrovir™ in 1% Soluplus in drinking water significantly suppressed herpes simplex virus-1 reactivation and viral genomic replication. Ad libitum oral delivery of sacrovir™ was effective in suppressing herpes simplex virus-1 reactivation in ocularly infected latent mice as measured by the numbers of mice shedding infectious virus at the ocular surface, numbers of trigeminal ganglia positive for infectious virus, number of corneas that had detectable infectious virus, and herpes simplex virus-1 genome copy numbers in trigeminal ganglia following reactivation. These results demonstrate the statistically significant effect of the prodrug on suppressing herpes simplex virus-1 reactivation in vivo. © The Author(s) 2015.

  11. PAQUIMETRIA ULTRA-SÔNICA DE CÓRNEAS DE CANINOS E SUÍNOS

    Directory of Open Access Journals (Sweden)

    Duvaldo Eurides

    2006-10-01

    Full Text Available Estudaram-se trinta olhos de caninos, adultos, machos e fêmeas, mestiços, submetidos a eutanásia e cedidos pela Faculdade de Medicina da Universidade Federal de Goiás (UFG e trinta de suínos, seis meses, machos e fêmeas, mestiços, abatidos no frigorífico Boa Sorte, no município de Goiânia. Os olhos enucleados pela técnica de exenteração foram acondicionados individualmente em câmaras úmidas (Filatov com solução fisiológica 0,9% e mantidos em caixa de isopor por um período máximo de seis horas. Dividiu-se a córnea de cada olho, para efeito das leituras, em cinco áreas (central, nasal superior, nasal inferior, temporal superior e temporal inferior. Procedeu-se às leituras digitais com o paquímetro ultra-sônico de Storz em três pontos para cada área, totalizando quinze vezes em cada olho. Os resultados obtidos das médias gerais foram, para caninos, de 704,21 ± 67,11 m. Os valores médios diferenciaram-se para cada ponto, sendo que a média obtida nas áreas centrais (670,70 ± 75,29 m foi a menos espessa e nas nasais inferiores (715,50 ± 79,52 m a mais espessa. Para os suínos, os resultados apontaram 700,31 ± 30,08 m. Os valores médios diferenciaram-se para cada ponto, sendo que a média obtida nas áreas nasais inferiores (669,63 ±85,79 m foi a menos espessa e nas temporais superiores(731,47m ± 64,06m a mais espessa. O método foi eficiente, seguro e simples. Os valores obtidos nas condições deste trabalho são inéditos, mas só servem como valores de referência para estas amostras, pois são dependentes da idade,do peso, do sexo, da raça, da dieta e até do horário do exame,variáveis estas que não se consideraram neste trabalho. PALAVRAS-CHAVES: Cão, paquimetria ultra-sônica, paquímetro de Störz, suíno.

  12. UN CASO DE DESORDEN DEL DESARROLLO SEXUAL EN UN CANINO MESTIZO

    Directory of Open Access Journals (Sweden)

    S. Valencia

    2017-01-01

    Full Text Available Los desórdenes del desarrollo sexual se pueden presentar en diferentes animales domésticos, aunque no son muy comunes. Se clasifican en tres grupos de anormalidades: del desarrollo cromosómico, del desarrollo gonadal y del sexo fenotípico, y presentan diferentes subcate - gorías. El objetivo de este trabajo fue describir las características fenotípicas, cromosómicas y anatómicas de los órganos reproductores de un paciente canino, aparentemente hembra, de 3 años de edad, con desorden del desarrollo sexual, que presentaba una protuberancia a nivel vaginal con sangrado y presencia de pus; en la anamnesis reportan comportamien - to de macho. Se realizó un examen general por sistemas, ecografía abdominal ventral, radiografía latero-lateral, cuadro hemático y cariotipo con bandas R-replicativas. Tras la evaluación se encontró un clítoris agrandado (pseudopene con orificio uretral que mostró resistencia a la colocación de una sonda. La radiografía mostró una estructura similar al hueso del pene y la ecografía reveló una estructura compatible con el cuello del útero en una hembra y una estructura lateral parecida al tejido gonadal. El cariotipo fue típico de un macho, compatible con un macho seudohermafrodita, lo cual permite clasificar al individuo como XY, con un desorden del desarrollo sexual fenotípico (78, XY según la nueva clasificación. Con las herramientas diagnósticas disponibles en Colombia es posible realizar un diagnóstico diferencial adecuado. Sin embargo, falta disponibilidad de pruebas diagnósticas específicas como FISH y mediciones serológicas.

  13. Crescimento de genótipos de frangos tipo caipira

    Directory of Open Access Journals (Sweden)

    R. C. Veloso

    2015-10-01

    Full Text Available RESUMOObjetivou-se com este trabalho comparar o padrão de crescimento, mediante ajustes das respectivas curvas de crescimento por modelos não lineares, bem como estudar o desenvolvimento de cortes de carcaça em relação ao peso da carcaça em diferentes genótipos de frangos tipo caipira. Foram utilizados 840 pintos de um dia, machos, distribuídos em delineamento inteiramente ao acaso, dos seguintes genótipos da linhagem Redbro: Caboclo, Carijó, Colorpak, Gigante Negro, Pesadão Vermelho, Pescoço Pelado e Tricolor. As aves foram alojadas em 28 boxes, sendo 30 aves/boxe, em galpão de alvenaria com acesso a um piquete de 45m², com quatro repetições. O peso corporal individual dos frangos foi medido ao nascer, aos 14, 28, 42, 56, 70 e 84 dias de idade. Para a determinação das curvas de crescimento do peso corporal das aves, os dados coletados foram avaliados por meio dos modelos não lineares: Brody, Gompertz, Logístico, Richards e von Bertalanffy. Foi empregado o PROC NLIN do SAS, utilizando-se o método interativo de Gauss-Newton. Os critérios usados para escolha do modelo de melhor ajuste da curva de crescimento foram o coeficiente de determinação, o desvio padrão assintótico, o desvio médio absoluto dos resíduos e o índice assintótico. As análises para obtenção dos coeficientes alométricos foram realizadas por meio do PROC GLM do SAS para os genótipos Carijó, Colorpak, Pesadão Vermelho, Pescoço Pelado e Tricolor. Foram avaliados os pesos da carcaça, do peito, das coxas, das sobrecoxas, das pernas e das asas das aves abatidas aos 85 dias de idade. Apenas as equações propostas por Gompertz, von Bertalanffy e Logístico atingiram a convergência, e o modelo proposto por von Bertalanffy foi o mais adequado para descrever o crescimento dos genótipos de frangos caipiras. Todos os cortes avaliados apresentaram crescimento tardio em relação ao peso da carcaça em genótipos de frangos tipo caipira.

  14. Two step culture for production of recombinant herpes simplex virus ...

    African Journals Online (AJOL)

    Herpes simplex virus type 2 (HSV-2) was the major cause of genital herpes in humans. The HSV-2 glycoprotein D (gD2) had been proved to be a potentially effective vaccine for treatment of genital herpes. The present study was to develop a two step culture to express the recombinant gD2 protein using the immobilized ...

  15. Pathogenesis of herpes simplex virus infections of the cornea

    NARCIS (Netherlands)

    J. Maertzdorf (Jeroen)

    2002-01-01

    textabstractThe identification of human herpes virus (HHV) infections can be traced back to ancient Greece where Herpes simplex vims (HSV) infections in humans were first documented. Hippocrates used the word "herpes", meaning to creep or crawl, to describe spreading skin lesions. Although the

  16. Determinación del efecto del gel de Aloe vera, sobre la glicemia en caninos sanos

    Directory of Open Access Journals (Sweden)

    María Mercedes Tamayo

    2011-02-01

    Full Text Available El papel desempeñado por la glucosa en los organismos es  fundamental, ya que es  la forma más importante por la cual los carbohidratos son absorbidos desde el tracto intestinal, con diversos factores que  influyen en los niveles de glucosa del  organismo.  La  causa más  frecuente  de hiperglucemia  en  los  perros  es  el  daño pancreático, hiperadrenocorticismo  e hipersomatotropismo. Así, al evaluar el efecto del gel de Aloe vera sobre  la glicemia en caninos,tras su administración oral, se utilizaron 18 ejemplares sanos que  fueron distribuidos al azar en seis grupos, en los que se administró diferentes sustancias y se procedió a realizar el exámen de glicemia cada 15 minutos  (min, obteniéndose que la administración de 50 mL de gel de Aloe vera, tanto a caninos normoglicémicos, como a los que se les indujo hiperglucemia, no produjo cambios significativos en los niveles de glucosa.Los  resultados obtenidos  bajo  las  condiciones planteadas en este estudio experimental no validaron el uso empírico tradicional del gel de Aloe vera.

  17. Clinical pattern of recurrent herpes simplex keratitis

    Directory of Open Access Journals (Sweden)

    Saini Jagjit

    1999-01-01

    Full Text Available Purpose: To document the clinical pattern in recurrent herpes simplex disease. Methods: Eyes with clinically documented pattern of corneal manifestation on more than one occasion were analysed. For each eye recruited, the clinical pattern of the disease at each recurrence of herpes simplex corneal disease, age, disease-free intervals, triggering factors, laterality and steroid abuse were noted and evaluated. Results: For an average follow up of 6.9 years, a recurrence rate of 0.6 episodes per year was observed. Disease-free intervals of 75.7 months for epithelial herpes simplex disease was considerably longer than the 21.3 months observed for stromal disease. Clinical pattern of recurrence was of the same type following first episode of disciform keratitis, epithelial keratitis and endothelitis in 84%, 72.7%, and 75% of the eyes respectively. Conclusion: Herpes simplex disease often recurs in the same manifest clinical pattern as the first episode. This clinical evidence provides additional support for the potential role of herpes simplex biotypes in determining manifestation of clinical disease pattern.

  18. Does circumcision influence recurrences in herpes genitalis?

    Directory of Open Access Journals (Sweden)

    Jerath V

    2009-01-01

    Full Text Available Background and Aims: The effect of therapeutic circumcision in men for preventing recurrences of herpes genitalis remains largely unelucidated despite its well documented albeit conflicting role in reducing the risk of acquiring sexually transmitted infections, including genital herpes. Methods: Twenty volunteer adult males with a history of recurrent herpes genitalis were included in the study after informed consent and circumcision was carried out. Twenty more adult males having recurrent herpes genitalis and registered in the clinic during the same period were selected as controls. All patients and controls were followed-up for recurrences of herpes genitalis. Results and Conclusions: Six patients and six controls did not follow-up. Seven patients reported no recurrences during 3-18 years, seven patients had two to six recurrences during 11-27 years of postcircumcision follow-up, 0.0080 (average recurrences per person per year as compared with 0.20 (average recurrences per person per year recorded before the circumcision. Two patients had first recurrence 11 years after the circumcision. In comparison, 14 controls had 0.17 (average recurrences per person per year, comparable with the number of recurrences in uncircumcised patients, and frequently at shorter intervals. Despite being a small study, the circumcision appears to reduce the number of recurrences on an average and evidently prolongs the disease-free period in between two recurrences.

  19. Designing herpes viruses as oncolytics

    Science.gov (United States)

    Peters, Cole; Rabkin, Samuel D

    2015-01-01

    Oncolytic herpes simplex virus (oHSV) was one of the first genetically-engineered oncolytic viruses. Because HSV is a natural human pathogen that can cause serious disease, it is incumbent that it can be genetically-engineered or significantly attenuated for safety. Here, we present a detailed explanation of the functions of HSV-1 genes frequently mutated to endow oncolytic activity. These genes are nonessential for growth in tissue culture cells but are important for growth in postmitotic cells, interfering with intrinsic antiviral and innate immune responses or causing pathology, functions dispensable for replication in cancer cells. Understanding the function of these genes leads to informed creation of new oHSVs with better therapeutic efficacy. Virus infection and replication can also be directed to cancer cells through tumor-selective receptor binding and transcriptional- or post-transcriptional miRNA-targeting, respectively. In addition to the direct effects of oHSV on infected cancer cells and tumors, oHSV can be “armed” with transgenes that are: reporters, to track virus replication and spread; cytotoxic, to kill uninfected tumor cells; immune modulatory, to stimulate antitumor immunity; or tumor microenvironment altering, to enhance virus spread or to inhibit tumor growth. In addition to HSV-1, other alphaherpesviruses are also discussed for their oncolytic activity. PMID:26462293

  20. DIAGNOSIS DAN TATA LAKSANA ENSEFALITIS HERPES SIMPLEKS

    Directory of Open Access Journals (Sweden)

    Tri Yuliantini

    2014-12-01

    Full Text Available Infeksi Herpes simpleks pada susunan saraf pusat (SSP merupakan infeksi SSP yang paling beratdan sering berakibat fatal. Angka kejadiannya diperkirakan 1 kasus per 250 000 sampai 500 000orang per tahun, sepertiganya terjadi pada anak-anak. Gejala dan tanda klinis pada fase awal sangattidak khas. Pemberian terapi yang terlambat membawa dampak terjadinya kecacatan permanen.Deteksi virus Herpes simpleks (VHS di dalam cairan serebrospinal dengan polymerase chain reactionmerupakan modalitas pilihan untuk diagnosis ensefalitis herpes simpleks (EHS. Asiklovir intravenamerupakan obat pilihan pertama. Pengobatan segera diberikan kepada pasien yang dicurigai menderitaEHS, kemudian pengobatan dapat dilanjutkan atau dihentikan sesuai konfirmasi laboratorium atauhasil biopsi otak. Pasien yang tidak diberikan antivirus atau pengobatannya terlambat angkakematiannya cukup tinggi.

  1. Benzalkonium Chloride Intoxication Mimicking Herpes Zoster Encephalitis

    Directory of Open Access Journals (Sweden)

    Ekrem Güler

    2011-06-01

    Full Text Available Benzalkonium chloride (BAC is a frequently used disinfectant and its most well-known side effect is contact dermatitis. In this report, two children who had vesicular dermatitis, headache, lethargy, fever and encephalopathy mimicking Herpes zoster encephalitis were presented. Their consciousness level improved on the second day. From the medical history it was understood that the mother had applied 20% BAC solution to the scalps of two children. The aim of the presentation of this report is to draw attention to the fact that BAC application to the scalp for treating pediculosis capitis may resemble the herpes encephalitis clinical picture.

  2. Preventing herpes simplex virus in the newborn.

    Science.gov (United States)

    Pinninti, Swetha G; Kimberlin, David W

    2014-12-01

    Genital herpes simplex virus (HSV) infections are very common worldwide. Approximately 22% of pregnant women are infected genitally with HSV, and most of them are unaware of this. The most devastating consequence of maternal genital herpes is HSV disease in the newborn. Although neonatal HSV infections remain uncommon, due to the significant morbidity and mortality associated with the infection, HSV infection in the newborn is often considered in the differential diagnosis of ill neonates. This review summarizes the epidemiology and management of neonatal HSV infections and discusses strategies to prevent HSV infection in the newborn. Copyright © 2014 Elsevier Inc. All rights reserved.

  3. Comparacion de la radiografia simple y la tomografia computarizada en el diagnostico de hernia discal tipo 1 en perros

    National Research Council Canada - National Science Library

    Donaires V., Rosmery; Diaz C., Diego; Chipayo G., Ysaac; Gavidia C., Cesar

    2013-01-01

    .... Se estudiaron 16 pacientes caninos cuya evaluacion neurologica revelo una disfuncion neurologica compatible a una compresion medular toracolumbar y una magnitud de lesion de grado III o superior...

  4. Un tipo ideal: capitalismo bancario

    OpenAIRE

    Gutiérrez Carranza, Claudio

    2014-01-01

    Después de Max Weber es un lugar común en metodología de las ciencias sociales hablar de “tipos ideales”. Como tales se entienden, a pesar de que hay todavía mucas disputas en cuanto a su naturaleza, construcciones abstractas que reporducen en forma pura o simplificada algún aspecto de la realidad para su mejor estudioo. Así, el “hombre económico” de la economía clásica, interesado sólo en utilizar su utilidad, es un ejemplo de este recurso analítico. En su variante más común, un tipo lógico ...

  5. Herpes zoster ophthalmicus with total ophthalmoplegia

    Directory of Open Access Journals (Sweden)

    Talwar S

    1990-01-01

    Full Text Available A case of unilateral herpes zoster ophthalmicus (HZO is reported with ipsilateral involvement of III, IV and VI cranial nerves which led to extra ocular muscles palsy presenting as total ophthalmopegia along with ptosis, cycloplegia and dilated non reactive pupil.

  6. Recurrent Herpes Zoster- A Marker of AIDS

    Directory of Open Access Journals (Sweden)

    Mazumdar Gautam

    2003-01-01

    Full Text Available A 32 year old female presented to us with herpes zoster involving the T 8 to T 10 dermatomes. She had a scar involving the same dermatomes on the other half of the body. Investigations revealed that both the patient and her husband were HIV positive with CD4 cell count less than 200.

  7. Herpes Simplex Esophagitis in Immunocompetent Hosts

    Directory of Open Access Journals (Sweden)

    Daniel Eymard

    1997-01-01

    Full Text Available Over four months, three cases of biopsy-proven herpes simplex esophagitis were seen at Centre hospitalier Pierre-Boucher, Longueuil, in young adult males with no evidence of immunosuppression and negative serological testing for antibody against the human immunodeficiency virus. Clinical presentation consisted of odynophagia, fever and retrosternal chest pain. All patients rapidly improved with acyclovir therapy.

  8. Disseminated Herpes Zoster with Meningo-encephalitis

    Directory of Open Access Journals (Sweden)

    R A Bumb

    1989-01-01

    Full Text Available A 65 year old, immunocompetent, male patient developed herpes zoster ophthalmicus associated with a generalized varicellifform euption and meningo-encephalitis. Meningo-encephalitis was diagnosed on the basis of CSF picture. The patient responded in seven clays to oral acyclovir (400 mg five times a day

  9. Antiviral therapy in herpes- virus infections

    African Journals Online (AJOL)

    Repro

    pesviruses — herpes simplex virus (HSV), varicella zoster virus (VZV) ... virus infections. Herpesviruses are commonly seen in clinical practice. This article discusses their management in some detail. MAIN TOPIC. 332 C M E June 2003 Vol.21 No.6. After primary infection, ... A typical primary attack lasts about 10 - 14 days.

  10. Herpes zoster: klinik, diagnostik og behandling

    DEFF Research Database (Denmark)

    Kofoed, Kristian; Rønholt, Finn; Gerstoft, Jan

    2011-01-01

    Herpes zoster (HZ) is a painful vesicular rash localized to one dermatome. Post-herpetic neuralgia (PHN) is persistent pain three months after the rash started. In recent years several Cochrane reviews and clinical studies on how to treat HZ and PHN have been published. These studies show...

  11. Forebyggelse af herpes zoster med vaccination

    DEFF Research Database (Denmark)

    Kofoed, Kristian; Rønholt, Finn; Gerstoft, Jan

    2011-01-01

    Herpes zoster (HZ) and post-herpetic neuralgia (PHN) are frequently occurring diseases in elderly and in immuno-compromised persons. The live attenuated HZ vaccine boosts an existing immune response, so that the already established varicella-zoster virus infection is kept latent. Vaccination has...

  12. Herpes simplex and mood: a prospective study.

    Science.gov (United States)

    Dalkvist, J; Wahlin, T B; Bartsch, E; Forsbeck, M

    1995-01-01

    The effect of mood, the common cold, amount of sleep, and sunshine on recurring herpes simplex virus (HSV) infection was investigated using daily self-reports over a 3-month period from 23 female and 15 male patients with genital herpes and 26 female and two male patients with oral herpes. Results showed recurring genital HSV infection to be preceded by reduced and decreasing overall emotional well being over a period of 10 days, with a temporary improvement in the middle of the period. This pattern was significantly represented by rated nervousness and rated alertness. Females showed more marked trends for reported mood than did the males, which could not be attributed to the menstrual cycle. Conversely, males showed a more marked, strongly significant fourth-order trend for reported amount of sleep, with nadirs on the 8th and the 3rd day before the recurrence. Neither exposure to sunshine nor the common cold showed any relation to recurrence of genital HSV infection. The common cold appeared as the major precipitating factor in oral herpes. Except for a significant fourth-order trend for rated alertness, no relationship between mood and subsequent onset was found. This negative finding was interpreted as a masking effect of the common cold. Two alternative physiological theories, the ganglion trigger theory and the skin trigger theory, were discussed in relation to present findings. It was suggested that various possible mediators between mood states and recurring herpes should be investigated using the present approach, with structured diaries as complement to the rating scales.

  13. OBTENCIÓN DE ANTICUERPOS POLICLONALES IgY ANTIPARVOVIRUS CANINO A PARTIR DE YEMA DE HUEVO DE GALLINA

    OpenAIRE

    Pinto, J.; Unidad de Investigaciones Agropecuarias (UNIDIA) Microbiología Agrícola y Veterinaria Facltad de Ciencias Pontificia Universidad Javeriana, Bogotá; Barco, M.; Unidad de Investigaciones Agropecuarias (UNIDIA) Microbiología Agrícola y Veterinaria Facltad de Ciencias Pontificia Universidad Javeriana, Bogotá; Afanador, M. C.; Unidad de Investigaciones Agropecuarias (UNIDIA) Microbiología Agrícola y Veterinaria Facltad de Ciencias Pontificia Universidad Javeriana, Bogotá; Merchán, A. M.; Unidad de Investigaciones Agropecuarias (UNIDIA) Microbiología Agrícola y Veterinaria Facltad de Ciencias Pontificia Universidad Javeriana, Bogotá; Montañez, M. F.; Purificación y Análisis de Fluidos Ltda. Bogotá,; Andrade, F.; Purificación y Análisis de Fluidos Ltda. Bogotá.; Torres, O.; Unidad de Investigaciones Agropecuarias (UNIDIA) Microbiología Agrícola y Veterinaria Facltad de Ciencias Pontificia Universidad Javeriana, Bogotá

    2005-01-01

    Inmunizando un grupo de diez gallinas de postura raza Lohmann de 16 semanas de edad con parvovirus canino (CPV) cepa vacunal, se obtuvieron anticuerpos IgY policlonales contra CPV en yema de huevo.En la extracción de los anticuerpos de la yema se requirieron dos pasos, el primero para la remoción de lípidos y el segundo para la precipitación de proteínas. Para la remoción de lípidos se usó el método PBS:Cloroformo y para la precipitación de los anticuerpos solubles (Inmunoglobulinas-IgY) se u...

  14. Comparison of three laboratorial tests for diagnosis of canine parvovirus infection Comparação de três testes laboratoriais para diagnóstico da infecção pelo parvovírus canino

    Directory of Open Access Journals (Sweden)

    M.M.O. Silva

    2013-02-01

    Full Text Available The aim of this study was to evaluate the rapid tests currently used for canine parvovirus (CPV diagnosis: hemagglutination test (HA, enzyme immunoassay (EIA and polymerase chain reaction (PCR. A total of 112 fecal samples collected from diarrheic puppies up to one year of age were tested. The EIA was able to detect CPV antigen in 44 samples. By HA, 32 samples tested highly positive with titers >128, eight tested weakly positive (titers 32 and 64 and 72 were negative (titers Avaliaram-se os métodos rápidos rotineiramente utilizados para diagnóstico da infecção por parvovírus canino (CPV: teste de hemaglutinação (HA, ensaio imunoenzimático (EIE e reação em cadeia pela polimerase (PCR. Um total de 112 amostras fecais de cães diarreicos com até um ano de idade foi testado. O EIE foi capaz de detectar o antígeno do CPV em 44 amostras. Por HA, 32 amostras foram consideradas fortemente positivas com títulos >128, oito fracamente positivas (títulos 32 e 64 e 72 negativas (títulos <16. Por PCR, 57 amostras foram positivas incluindo 13 EIE-negativas e 19 HA-negativas. A melhor correlação foi observada entre EIE e PCR (88,4%. Os testes foram capazes de detectar todos os tipos de CPV, incluindo o CPV-2c. Considerando-se que em 23%-33% dos filhotes com enterite a infecção por CPV não foi diagnosticada pelos testes de EIE e HA, os resultados negativos nos testes de detecção de antígeno devem ser confirmados por meio de métodos moleculares.

  15. Base de datos de medidas electrocardiográficas para caninos residentes en la ciudad de Bogotá

    Directory of Open Access Journals (Sweden)

    Mauricio Ortega Tamayo

    2006-12-01

    Full Text Available El siguiente trabajo presenta la base de datos Vetuan I, que contiene las medidas electrocardiográficas de 100 pacientes caninos sin anomalías cardíacas examinados en la Clínica Veterinaria Veteriland de la ciudad de Bogotá, y atendidos por personal de la Facultad de Medicina Veterinaria de la Universidad Antonio Nariño, Bogotá. Las medidas que se incluyen dentro de la base de datos, comprenden la duración y amplitud de de las ondas que componen un ciclo cardíaco en cada uno de los registros electrocardiográficos de los pacientes examinados, utilizando como referencia las tres derivaciones bipolares, así como, las medidas de los ejes cardíacos. El propósito principal del trabajo es actualizar los datos de soporte al diagnóstico que se han venido utilizando a partir de la tabla de referencia implementada en los años 60 en Estados Unidos. Dentro de resultados se puede apreciar que las medidas que hacen parte de la base de datos Vetuan I, difieren del rango de medidas que se han venido tomando como referencia a partir de la tabla desarrollada en los años 60, por lo que se deduce que la dinámica cardiaca de los caninos depende fuertemente de los factores ambientales en que viven, específicamente la altura sobre el nivel del mar.

  16. Encefalomielite aguda disseminada – pós-infecção por Herpes Vírus 6

    Directory of Open Access Journals (Sweden)

    Joana Amorim

    2016-09-01

    Discussão: Trata-se de um caso clínico de ADEM com atingimento predominantemente medular, obrigando ao diagnóstico diferencial com outros quadros de paraparésia flácida de instalação aguda ou subaguada. Pretende -se alertar para a possibilidade de ocorrência deste tipo de manifestações neurológicas após infeção por herpes vírus 6.

  17. Comparación entre el Método Directo y la Fórmula de Friedewald para Determinar los Niveles de Colesterol LDL en Caninos

    OpenAIRE

    Osorio, José Henry; Laboratorio de Bioquímica Clínica y Patología Molecular, Departamento de Ciencias Básicas de la Salud, Universidad de Caldas, Manizales, Colombia; Suárez, Yirly Johanna; Laboratorio de Bioquímica Clínica y Patología Molecular, Departamento de Ciencias Básicas de la Salud, Universidad de Caldas, Manizales, Colombia; Vinasco, Jazmín; Laboratorio de Bioquímica Clínica y Patología Molecular, Departamento de Ciencias Básicas de la Salud, Universidad de Caldas, Manizales, Colombia

    2014-01-01

    El objetivo del estudio fue comparar el método Directo con la fórmula de Friedewald para la determinación de colesterol LDL en caninos. Se tomaron 185 muestras de sangre de caninos adultos en ayuno y sin restricción de sexo. Se extrajo el suero y se determinaron los niveles de colesterol LDL con los dos métodos. El promedio, desviación estándar y valores mínimo y máximo por el método Directo fueron de 49.2 ± 16.7, 14.6 y 96.0 mg/dl, respectivamente, y por la fórmula de Friedewald fueron de 65...

  18. Análisis, estrategias, plan d e marketing e implementación de un nuevo producto canino eukanuba en el mercado ecuatoriano

    OpenAIRE

    Vaca Rivas, Maria Paola; Zunino Cedeño, Giancarlo; Pastor Lopez, Bolivar

    2009-01-01

    Actualmente el mercado de consumo de alimento para mascotas ha tomado un rol importante en nuestra sociedad debido al desarrollo de nuevas creencias alimenticias y descubrimientos significativos de beneficios nutricionales como prácticos. Nosotros como amantes del mundo canino hemos decidido enfocarnos en este campo con el objetivo de responder a ciertas interrogantes: ¿Existe espacio en el mercado ecuatoriano para la introducción de un nuevo producto balanceado? ¿Los consumidores r...

  19. Evaluación del tiempo de recuperación de dos protocolos anestésicos en la esterilización de caninos machos

    OpenAIRE

    Vanegas Avecillas, Bolívar Gonzalo

    2015-01-01

    El presente proyecto tiene por objetivo evaluar el tiempo de recuperación en la esterilización de caninos machos, utilizando dos asociaciones de protocolos anestésicos: (Ketamina + Acepromacina) y (Ketamina + Acepromacina + Propofol), obteniendo un resultado alta mente significante en los tiempos de recuperación de los pacientes con (Ketamina + Acepromacina + Propofol). This project aims to assess the recovery time in the sterilization of male dogs, using two protocols associations anesthe...

  20. Improving immunogenicity and efficacy of vaccines for genital herpes containing herpes simplex virus glycoprotein D.

    Science.gov (United States)

    Awasthi, Sita; Shaw, Carolyn; Friedman, Harvey

    2014-12-01

    No vaccines are approved for prevention or treatment of genital herpes. The focus of genital herpes vaccine trials has been on prevention using herpes simplex virus type 2 (HSV-2) glycoprotein D (gD2) alone or combined with glycoprotein B. These prevention trials did not achieve their primary end points. However, subset analyses reported some positive outcomes in each study. The most recent trial was the Herpevac Trial for Women that used gD2 with monophosphoryl lipid A and alum as adjuvants in herpes simplex virus type 1 (HSV-1) and HSV-2 seronegative women. Unexpectedly, the vaccine prevented genital disease by HSV-1 but not HSV-2. Currently, HSV-1 causes more first episodes of genital herpes than HSV-2, highlighting the importance of protecting against HSV-1. The scientific community is conflicted between abandoning vaccine efforts that include gD2 and building upon the partial successes of previous trials. We favor building upon success and present approaches to improve outcomes of gD2-based subunit antigen vaccines.

  1. Mucosal Herpes Immunity and Immunopathology to Ocular and Genital Herpes Simplex Virus Infections

    Directory of Open Access Journals (Sweden)

    Aziz Alami Chentoufi

    2012-01-01

    Full Text Available Herpes simplex viruses type 1 and type 2 (HSV-1 and HSV-2 are amongst the most common human infectious viral pathogens capable of causing serious clinical diseases at every stage of life, from fatal disseminated disease in newborns to cold sores genital ulcerations and blinding eye disease. Primary mucocutaneous infection with HSV-1 & HSV-2 is followed by a lifelong viral latency in the sensory ganglia. In the majority of cases, herpes infections are clinically asymptomatic. However, in symptomatic individuals, the latent HSV can spontaneously and frequently reactivate, reinfecting the muco-cutaneous surfaces and causing painful recurrent diseases. The innate and adaptive mucosal immunities to herpes infections and disease remain to be fully characterized. The understanding of innate and adaptive immune mechanisms operating at muco-cutaneous surfaces is fundamental to the design of next-generation herpes vaccines. In this paper, the phenotypic and functional properties of innate and adaptive mucosal immune cells, their role in antiherpes immunity, and immunopathology are reviewed. The progress and limitations in developing a safe and efficient mucosal herpes vaccine are discussed.

  2. Mucosal Herpes Immunity and Immunopathology to Ocular and Genital Herpes Simplex Virus Infections

    Science.gov (United States)

    Chentoufi, Aziz Alami; BenMohamed, Lbachir

    2012-01-01

    Herpes simplex viruses type 1 and type 2 (HSV-1 and HSV-2) are amongst the most common human infectious viral pathogens capable of causing serious clinical diseases at every stage of life, from fatal disseminated disease in newborns to cold sores genital ulcerations and blinding eye disease. Primary mucocutaneous infection with HSV-1 & HSV-2 is followed by a lifelong viral latency in the sensory ganglia. In the majority of cases, herpes infections are clinically asymptomatic. However, in symptomatic individuals, the latent HSV can spontaneously and frequently reactivate, reinfecting the muco-cutaneous surfaces and causing painful recurrent diseases. The innate and adaptive mucosal immunities to herpes infections and disease remain to be fully characterized. The understanding of innate and adaptive immune mechanisms operating at muco-cutaneous surfaces is fundamental to the design of next-generation herpes vaccines. In this paper, the phenotypic and functional properties of innate and adaptive mucosal immune cells, their role in antiherpes immunity, and immunopathology are reviewed. The progress and limitations in developing a safe and efficient mucosal herpes vaccine are discussed. PMID:23320014

  3. Oral sores: a rare presentation of Herpes zoster

    Directory of Open Access Journals (Sweden)

    Sunder Nagakeerthana

    2016-09-01

    Full Text Available Herpes zoster is one of the common dermatological diseases in elderly. It is clinically diagnosed by the presence of vesicles in a zosteriform pattern, appearing along one or two dermatomes. We report a rare presentation of herpes zoster occurring over hard palate. Early recognition of such rare presentations of Herpes zoster and treatment with antivirals at the appropriate time is the most essential step required to decrease the morbidity.

  4. Herpes zoster duplex bilateralis in an immunocompetent host

    Directory of Open Access Journals (Sweden)

    Pratik Gahalaut

    2012-01-01

    Full Text Available Varicella zoster virus causes both chicken pox and herpes zoster. The phenomenon of herpes zoster occurring concurrently in two non-contiguous dermatomes involving different halves of the body is termed herpes zoster duplex bilateralis (HZDB. Few cases, reported in the literature, were seen in either an immunosuppressed host or in the older age group. Here we present a case of HZDB in an immunocompetent host, probably the first in India.

  5. Herpes zoster duplex bilateralis in an immunocompetent host

    Science.gov (United States)

    Gahalaut, Pratik; Chauhan, Sandhya

    2012-01-01

    Varicella zoster virus causes both chicken pox and herpes zoster. The phenomenon of herpes zoster occurring concurrently in two non-contiguous dermatomes involving different halves of the body is termed herpes zoster duplex bilateralis (HZDB). Few cases, reported in the literature, were seen in either an immunosuppressed host or in the older age group. Here we present a case of HZDB in an immunocompetent host, probably the first in India. PMID:23130258

  6. 2014 UK national guideline for the management of anogenital herpes.

    Science.gov (United States)

    Patel, Raj; Green, John; Clarke, Emily; Seneviratne, Kanchana; Abbt, Naomi; Evans, Ceri; Bickford, Jane; Nicholson, Marian; O'Farrell, Nigel; Barton, Simon; FitzGerald, Mark; Foley, Elizabeth

    2015-10-01

    These guidelines concern the management of anogenital herpes simplex virus infections in adults and give advice on diagnosis, management, and counselling of patients. This guideline replaces the 2007 BASHH herpes guidelines and includes new sections on herpes proctitis, key points to cover with patients regarding transmission and removal of advice on the management of HSV in pregnancy which now has a separate joint BASHH/RCOG guideline. © The Author(s) 2015.

  7. Tipo y frecuencia de agresividad canina a humanos en pacientes de una clinica veterinaria en lima

    National Research Council Canada - National Science Library

    Rosas M. Sal, Eduardo; Fernandez P., Viviana; Lira M., Boris; Santiani A., Alexei

    2010-01-01

    Palabras clave: caninos, agresividad, humanos, dominancia The purpose of this study was to determine the type and frequency of aggressiveness directed to the human, and to identify the situations in which they occur...

  8. Aislamiento e identificación bioquímica de microorganismos bacterianos a partir de infecciones de piel en caninos

    Directory of Open Access Journals (Sweden)

    Iovana Castellanos L.

    2011-12-01

    Full Text Available Las dermatitis bacterianas o piodermas en caninos son ocasionadas por microorganismos patógenos, de los cuales el Staphylococcus intermedius es el más frecuente. Los tratamientos empíricos de este grupo de enfermedades permiten la proliferación de cepas resistentes de importancia en salud pública como es el caso del S. aureus. De igual forma, el riesgo de zoonosis reversa a partir de mascotas portadoras de cepas resistentes crea un serio problema de salud pública que requiere vigilancia epidemiológica. El objetivo de la investigación fue aislar e identificar bioquímicamente los microorganismos presentes en infecciones de piel en caninos; para esto se obtuvieron las muestras de caninos con problemas dermatológicos, y se identificaron los microorganismos bacterianos involucrados utilizando el kit de identificación rápida BBL Crystal para grampositivos. Los resultados obtenidos demostraron que el 80% de los aislamientos correspondieron a S. intermedius. Sin embargo, es necesario realizar estudios moleculares para relacionar la severidad de las lesiones dermatológicas con la identificación de los estafilococos presentes en el pioderma, y así establecer medidas de control, tratamiento y profilaxis.

  9. Herpes Zoster Duplex Bilateralis in a Patient with Breast Cancer

    Science.gov (United States)

    Yoo, Kwang Ho; Park, Ju Hee; Kim, Myeung Nam; Song, Kye Yong

    2009-01-01

    The skin lesion of herpes zoster is classically limited to a single dermatome, and most cases of multi-dermatomal herpes zoster have contiguous skin lesions. Noncontigous multi-dermatomal herpes zoster is very rare in both immunocompetent and immunosuppressed persons. The phenomenon of zoster occurring in two non-contiguous dermatomes has been referred to as zoster duplex unilateralis or bilateralis. We report here on a case of herpes zoster duplex bilateralis in a 49-year-old woman who had previously received chemotherapy for breast cancer treatment. PMID:19688072

  10. Inactivation of Herpes Simplex Viruses by Nonionic Surfactants

    Science.gov (United States)

    Asculai, Samuel S.; Weis, Margaret T.; Rancourt, Martha W.; Kupferberg, A. B.

    1978-01-01

    Nonionic surface-active agents possessing ether or amide linkages between the hydrophillic and hydrophobic portions of the molecule rapidly inactivated the infectivity of herpes simplex viruses. The activity stemmed from the ability of nonionic surfactants to dissolve lipid-containing membranes. This was confirmed by observing surfactant destruction of mammalian cell plasma membranes and herpes simplex virus envelopes. Proprietary vaginal contraceptive formulations containing nonionic surfactants also inactivated herpes simplex virus infectivity. This observation suggests that nonionic surfactants in appropriate formulation could effectively prevent herpes simplex virus transmission. Images PMID:208460

  11. Development history of herpes simplex encephalitis

    Directory of Open Access Journals (Sweden)

    Jia-wei WANG

    2014-08-01

    Full Text Available Herpes simplex encephalitis (HSE is an acute central nervous system infection caused by herpes simplex virus (HSV. Early clinical manifestations mainly include fever, headache and unconsciousness; when progressing, psychiatric symptoms can occur. Death or serious neurological sequelae will happen if not treated. With the development of laboratory tests and imaging techniques, the early diagnosis of HSE is possible. Even though imaging with temporal lobe abnormal signal has the implication to HSE, the application of polymerase chain reaction (PCR in detecting HSV DNA in cerebrospinal fluid is currently the "gold standard" to diagnose HSE. Once diagnosed, acyclovir must be given as soon as possible, as delayed treatment will result in a poor outcome. doi: 10.3969/j.issn.1672-6731.2014.08.003

  12. Decompressive craniectomy in herpes simplex encephalitis

    Directory of Open Access Journals (Sweden)

    Muhammed Jasim Abdul Jalal

    2015-01-01

    Full Text Available Intracranial hypertension is a common cause of morbidity in herpes simplex encephalitis (HSE. HSE is the most common form of acute viral encephalitis. Hereby we report a case of HSE in which decompressive craniectomy was performed to treat refractory intracranial hypertension. A 32-year-old male presented with headache, vomiting, fever, and focal seizures involving the right upper limb. Cerebrospinal fluid-meningoencephalitic profile was positive for herpes simplex. Magnetic resonance image of the brain showed swollen and edematous right temporal lobe with increased signal in gray matter and subcortical white matter with loss of gray, white differentiation in T2-weighted sequences. Decompressive craniectomy was performed in view of refractory intracranial hypertension. Decompressive surgery for HSE with refractory hypertension can positively affect patient survival, with good outcomes in terms of cognitive functions.

  13. Managing recurrent genital herpes with acyclovir

    OpenAIRE

    Bedi T

    1995-01-01

    Seventy five patients of recurrent genital herpes (RGH) treated with oral or topical acyclovir and placebo were compared and followed for periods ranging 4 to 8 years in a prospective study. Oral acyclovir definitely helps RGH patients; it shortens healing time; postpones recurrences and instills confidence in the patients. There is sufficient evidence that RGH dies a natural death with time as seen after 8 years follow up in placebo group patients. Topical use of acyclovir cream is not as us...

  14. Herpes associated erythema multiforme annularis concentricum

    Directory of Open Access Journals (Sweden)

    Kuldeep C

    1995-01-01

    Full Text Available A young man had large, concentric plaques over the back and extensors of forearms for eight weeks. Past history suggested recurrent herpes labialis. Serum anti HSV-1 IgG titre was raised to 32 micrograms/l and histopathology of an active lesion suggested erythema multiforme. Symptomatic treatment and oral zinc therapy subsided EM lesions but concentric depigmentation developed after healing

  15. Herpes Zoster in a Healthy Child

    Directory of Open Access Journals (Sweden)

    Ahu Çiler Çıkım

    2009-12-01

    Full Text Available Varicella zoster virus (VZV is the causing agent of chickenpox which is common in children. Herpes zoster (HZ is a latent infection that is caused by VZV, which is localized in the cells of dorsal root ganglions. HZ is rare in childhood and is especially encountered in immunosuppressed children. Here, an immunocompetent child with HZ is presented and the clinical symptoms, treatment and complications of the infection are reviewed.

  16. Ramsay hunt syndrome (herpes zoster oticus

    Directory of Open Access Journals (Sweden)

    S Karthiga Kannan

    2012-01-01

    Full Text Available Ramsay Hunt syndrome (RHS is defined as an acute peripheral facial neuropathy caused by the reactivated latent varicella zoster virus (VZV in the geniculate ganglion; characterized with erythematous vesicular rash of the skin of the ear canal, auricle, facial skin, oral mucosa and facial palsy (also known as herpes zoster oticus. This article reports a case of Ramsay Hunt Syndrome (RHS in a 37-year-old male patient depicting the classical signs.

  17. Hyperaesthesia Following Genital Herpes: A Case Report

    Directory of Open Access Journals (Sweden)

    Catriona Ooi

    2011-01-01

    Full Text Available We report an adult female patient who presented with sacral radiculopathy as incapacitating dysthesias following primary genital herpes simplex, which later recurred. Despite use of systemic antiviral treatment, the painful syndrome in our patient persisted. The success in treatment was seen only after the addition of amitriptyline hydrochloride. The case is being presented here for its rare manifestation and novel use of amitriptyline hydrochloride.

  18. Herpes simplex encephalitis : from virus to therapy.

    Science.gov (United States)

    Rozenberg, Flore; Deback, Claire; Agut, Henri

    2011-06-01

    Herpes simplex virus (HSV) is the cause of herpes simplex encephalitis (HSE), a devastating human disease which occurs in 2-4 cases per million/year. HSE results either from a primary infection or virus reactivation, in accordance with the common pattern of HSV infection which is a chronic lifelong process. However its pathophysiology remains largely unknown and its poor prognosis is in contrast with the usually good tolerance of most clinical herpetic manifestations. HSE is due to HSV type 1 (HSV-1) in most cases but HSV type 2 (HSV-2) may be also implicated, especially in infants in the context of neonatal herpes. Polymerase chain reaction detection of HSV DNA in cerebrospinal fluid is the diagnosis of choice for HSE. Acyclovir, a nucleoside analogue which inhibits viral DNA polymerase activity, is the reference treatment of HSE while foscarnet constitutes an alternative therapy and the efficacy of cidofovir is currently uncertain in that context. The emergence of HSV resistance to acyclovir, a phenomenon which is mainly observed among immunocompromised patients, is a current concern although no case of HSE due to an acyclovir-resistant HSV strain has been reported to date. Nevertheless the identification and development of novel therapeutic strategies against HSV appears to be a non dispensable objective for future research in virology.

  19. Herpes zoster oticus: A rare clinical entity

    Directory of Open Access Journals (Sweden)

    Shailesh Gondivkar

    2010-01-01

    Full Text Available Herpes zoster oticus also known as Ramsay Hunt syndrome is a rare complication of herpes zoster in which reactivation of latent varicella zoster virus infection in the geniculate ganglion causes otalgia, auricular vesicles, and peripheral facial paralysis. Ramsay Hunt syndrome is rare in children and affects both sexes equally. Incidence and clinical severity increases when host immunity is compromised. Because these symptoms do not always present at the onset, this syndrome can be misdiagnosed. Although secondary to Bell′s palsy in terms of the cause of acute atraumatic peripheral facial paralysis, Ramsay Hunt syndrome, with incidence ranged from 0.3 to 18%, has a worse prognosis. Herpes zoster oticus accounts for about 12% cases of facial palsy, which is usually unilateral and complete and full recovery occurs in only about 20% of untreated patients. The most advisable method to treat Ramsay Hunt syndrome is the combination therapy with acyclovir and prednisone but still not promising, and several prerequisites are required for better results. We present a case of 32-year-old man suffering from Ramsay Hunt syndrome with grade V facial palsy treated effectively with rehabilitation program, after the termination of the combination therapy of acyclovir and prednisone.

  20. Tumores testiculares caninos : a propósito de dos casos clínicos

    OpenAIRE

    Martí, S

    2010-01-01

    Los tumores testiculares tienen una mayor incidencia en la especie canina que en otras especies y son una patología habitual en la clínica diaria, aunque generalmente son hallazgos de la exploración física. La mayoría de los tumores testiculares son benignos, a diferencia de medicina humana donde este tipo de tumores son potencialmente malignos. Los síntomas clínicos varían según la actividad hormonal del tumor; los tumores de células de Sertoli y los seminomas pueden secretar mayor cantidad ...

  1. Herpes simplex virus type 1 is the leading cause of genital herpes in New Brunswick.

    Science.gov (United States)

    Garceau, Richard; Leblanc, Danielle; Thibault, Louise; Girouard, Gabriel; Mallet, Manon

    2012-01-01

    Little is known about the role of herpes simplex virus (HSV) type 1 (HSV1) in the epidemiology of genital herpes in Canada. Data on herpes viral cultures for two consecutive years obtained from L'Hôpital Dr GL Dumont, which performs all the viral culture testing in New Brunswick, were reviewed. It was hypothesized that HSV1 was the main cause of genital herpes in New Brunswick. Samples of genital origin sent to the laboratory for HSV culture testing between July 2006 and June 2008 were analyzed. Samples from an unspecified or a nongenital source were excluded from analysis. Multiple positive samples collected from the same patient were pooled into a single sample. HSV was isolated from 764 different patients. HSV1 was isolated in 62.6% of patients (male, 55%; female, 63.8%). HSV1 was isolated in 73.2% of patients 10 to 39 years of age and in 32% of patients ≥40 years of age. The difference in rates of HSV1 infection between the 10 to 39 years of age group and the ≥40 years of age group was statistically significant (Pgenital site. Significant rate differences were demonstrated between the groups 10 to 39 years of age and ≥40 years of age. Little is known about the role of herpes simplex virus (HSV) type 1 (HSV1) in the epidemiology of genital herpes in Canada. Data on herpes viral cultures for two consecutive years obtained from L’Hôpital Dr GL Dumont, which performs all the viral culture testing in New Brunswick, were reviewed. It was hypothesized that HSV1 was the main cause of genital herpes in New Brunswick. Samples of genital origin sent to the laboratory for HSV culture testing between July 2006 and June 2008 were analyzed. Samples from an unspecified or a nongenital source were excluded from analysis. Multiple positive samples collected from the same patient were pooled into a single sample. HSV was isolated from 764 different patients. HSV1 was isolated in 62.6% of patients (male, 55%; female, 63.8%). HSV1 was isolated in 73.2% of patients 10 to

  2. Relação entre a distância intercanina de humanos e o sexo, fenótipo cor da pele e a idade em marcas de mordida

    OpenAIRE

    Almeida Junior, Erasmo Cerqueira de

    2011-01-01

    Dentre as várias funções do Odontolegista estão a identificação e a interpretação de marcas de mordidas, presentes na pele da vítima ou do agressor ou em objetos e alimentos encontrados na cena do crime, sendo os dentes anteriores os mais comumente observados nessas lesões, principalmente os caninos. O objetivo deste estudo foi analisar a distância intercanina com relação ao sexo, fenótipo cor da pele e idade, além de avaliar o nível de acerto e segurança da metodologia utiliza...

  3. Valores hematológicos pre y postejercicio por sexo y por edad en caninos que practican agility en Antioquia

    Directory of Open Access Journals (Sweden)

    Silvia Posada Arias

    2013-06-01

    Full Text Available El objetivo del estudio es describir variables hematológicas pre y postejercicio en caninos practicantes de agility, y el efecto de factores como el sexo y la edad sobre estos parámetros. Se muestrearon 40 caninos durante el 2012 de cualquier sexo y edad, con mínimo seis meses de práctica en Antioquia. Se tomó una muestra de sangre venosa en tres momentos: en reposo, inmediatamente culminado el ejercicio y 30 min después del ejercicio. En Statgraphics versión 15.0 se empleó análisis de varianza con tres factores (sexo, edad y momento de toma de la muestra para evaluar su efecto sobre la línea roja, blanca y plaquetas. El nivel de confianza fue del 95 %, y se empleó el procedimiento de comparaciones múltiples (diferencia mínima significativa. Los eritrocitos y el volumen corpuscular medio presentaron diferencias significativas (p < 0,05 para cada una de las interacciones (sexo y edad en cada uno de los tres momentos. La hemoglobina no presentó diferencias significativas en ninguno de los factores e interacciones evaluadas. El recuento leucocitario en las diferentes edades mostró diferencias significativas (p < 0,05. Los neutrófilos y linfocitos presentaron diferencias significativas entre las distintas edades (p < 0,05 y los eosinófilos no presentaron diferencias significativas respecto a las variables del estudio. Las variaciones hematológicas postejercicio se deben a predominio simpático y liberación de catecolaminas, las cuales estimulan esplenocontracción y liberación de eritrocitos del bazo. En la línea blanca, la liberación de epinefrina en respuesta a miedo, excitación o ejercicio súbito es la responsable de la leucocitosis y neutrofilia fisiológica.

  4. Clinical and morphological characteristics of herpes zoster in south India

    Directory of Open Access Journals (Sweden)

    Dubey Anand

    2005-01-01

    Full Text Available One hundred and seven cases (6 children and 101 adults of herpes zoster were recruited over a period of two years. The frequency of herpes zoster amongst skin OPD cases was found to be 0.34 per cent. The male to female ratio was 1.74:1. The most common prodromal symptom seen was paresthesia in 25 (23.36% cases followed by itching in 21 (19.62% cases.Most common presenting complaint was pain in 97 (90.65% cases. Ninety nine cases had classical herpes zoster followed by necrotic / ulcerated herpes zoster in 5 cases and hemorrhagic herpes zoster in 3 cases. Thoracic dermatome was the most common dermatome involved in 64 (59.8% cases followed by cervical in 17 (15.8% cases. Unidermatomal involvement was seen in 81 (75.7% cases, followed by multidermatomal in 18 (16.8% cases and disseminated in 8 (7.4% cases. Forty six cases were screened for HIV, out of them; six cases (4 males, 2 females were seropositive for HIV. Classical herpes zoster was a feature in four cases; however, one case each also had necrotic and hemorrhagic form of herpes zoster. To conclude, herpes zoster commonly occurs in young adults in India with presenting symptoms such as pain, itching and fever.

  5. knowledge of genital herpes infection among antenatal clinic

    African Journals Online (AJOL)

    2009-07-07

    Jul 7, 2009 ... ABSTRACT. Background: Herpes simplex virus (HSV) is a major cause of genital ulcer disease worldwide and a significant factor for increased risk of acquisition and transmission of the Human Immune Deficiency Virus (HIV). The determination of the level of knowledge of genital herpes is necessary for the ...

  6. Frequency of Herpes Zoster Recurrence in Central District of Korea.

    Science.gov (United States)

    Ha, Jae Won; Lee, Jin Yong; Her, Young; Kim, Chul Woo; Kim, Sang Seok

    2017-10-01

    Herpes zoster is characterized by unilateral grouped vesicles along the distribution of a dermatome. A global recurrence rate as low as 0.5%∼6.2% has been reported for herpes zoster. The recurrence of herpes zoster is higher in immunocompromised patients and older patients. The purpose of this study is to assess the frequency of herpes zoster recurrence and factors that can influence its recurrence. From January 2005 to December 2015, 14,343 patients with herpes zoster were enrolled in this study. The patients were diagnosed at Hallym University Medical Centers and Kangwon National University Hospital in Seoul, Gyeonggi, and Gangwon. Herpes zoster recurrence and patient characteristics were surveyed by medical record review and a telephonic survey. The overall frequency of herpes zoster recurrence was 1.18%. The frequency of recurrence was higher in women than in men. It was also higher in patients aged 50∼70 years than in patients who were younger or older than this. Additionally, we assessed that the frequency of recurrence was statistically higher in patients with a compromised immune system and in patients who experienced longer lasting pain during their first episode. The frequency of herpes zoster recurrence is more common in women, older age, patient with longer pain duration and immunocompromised patients.

  7. Prodromal herpes zoster mimicking odontalgia – A diagnostic ...

    African Journals Online (AJOL)

    Herpes zoster (shingles) is caused by reactivation of the latent varicella zoster virus which is present due to an earlier varicella infection (chicken-pox). Herpes Zoster is a less common and endemic disease than varicella, although factors causing reactivation are still not well known, but it occurs in older and/or ...

  8. The incidence of neonatal herpes in The Netherlands.

    NARCIS (Netherlands)

    Poeran, J.; Wildschut, H.; Gaytant, M.A.; Galama, J.M.D.; Steegers, E.A.P.; Meijden, W.I. van der

    2008-01-01

    BACKGROUND: In The Netherlands the incidence of neonatal herpes was 2.0-2.9 per 100,000 live births during the period 1981-1998. The low incidence warranted a rather conservative prevention policy. OBJECTIVES: To monitor for potential changes in the incidence of neonatal herpes in The Netherlands

  9. Knowledge of genital herpes infection among antenatal clinic ...

    African Journals Online (AJOL)

    Background: Herpes simplex virus (HSV) is a major cause of genital ulcer disease worldwide and a significant factor for increased risk of acquisition and transmission of the Human Immune Deficiency Virus (HIV). The determination of the level of knowledge of genital herpes is necessary for the design and implementation of ...

  10. Herpes Simplex Virus type 2 Infection among Females in Enugu ...

    African Journals Online (AJOL)

    BACKGROUND: Herpes simplex virus type 2 infection is life long with manifestation in a small proportion of those infected. It has presented public health concern because of its progressively increasing prevalence which some authorities say is of epidemic proportion in developing countries. Herpes simplex virus type 2 has ...

  11. Operculum syndrome: unusual feature of herpes simplex encephalitis

    NARCIS (Netherlands)

    van der Poel, J. C.; Haenggeli, C. A.; Overweg-Plandsoen, W. C.

    1995-01-01

    Herpes simplex encephalitis in adults and young patients carries a high mortality and morbidity. Its presentation may be nonspecific, sometimes hampering early diagnosis. Two young children are reported with herpes simplex encephalitis in whom the operculum syndrome was an outstanding feature. This

  12. Herpes Zoster ophthalmicus and HIV seropositivity in South-south ...

    African Journals Online (AJOL)

    Herpes zoster is a painful vesiculobullous dermatitis which occurs as a result of previously established varicella zoster virus infection. It is a well established fact that Herpes zoster ophthalmicus is a well known marker of human immune deficiency virus infection even in Africans. The aim of this study is to determine if indeed ...

  13. Childhood herpes zoster: A clustering of ten cases

    Directory of Open Access Journals (Sweden)

    Prabhu Smitha

    2009-01-01

    Full Text Available Herpes zoster occurs due to reactivation of the latent varicella zoster virus and is usually a disease of the elderly. Childhood herpes zoster is believed to be rare, though recent studies suggest increasing incidence in children. Here we report ten cases of childhood herpes zoster, seven of which occurred within a short span of six months, at a tertiary care level hospital in Pokhara, Nepal. Only three of the ten children reported previous history of varicella infection and none was immunized against varicella. Though childhood herpes zoster accounted for less than 1% of the total zoster cases in the past, recent reports show an increase in the number of cases in apparently healthy children. So far, no studies have been done linking childhood herpes zoster with HIV, though there are many studies linking it with other immunocompromised conditions.

  14. Status of prophylactic and therapeutic genital herpes vaccines.

    Science.gov (United States)

    Awasthi, Sita; Friedman, Harvey M

    2014-06-01

    A half billion people have genital herpes infections worldwide. Approximately one-fifth of American women between ages 14 and 49 are HSV-2 seropositive. The development of an effective genital herpes vaccine is a global health necessity based on the mental anguish genital herpes causes for some individuals, the fact that pregnant women with genital herpes risk transmitting infection to their newborn children, and the observation that HSV-2 infection is associated with a 3-fold to 4-fold increased probability of HIV acquisition. We review the strengths and limitations of preclinical animal models used to assess genital herpes vaccine candidates and the goals of prophylactic and therapeutic vaccines. We also discuss the current pipeline of vaccine candidates and lessons learned from past clinical trials that serve as a stimulus for new strategies, study designs and endpoint determinations. Copyright © 2014 Elsevier B.V. All rights reserved.

  15. Recidiverende erythema multiforme udløst af herpes simplex-virus

    DEFF Research Database (Denmark)

    Vestergård Grejsen, Dorthe; Henningsen, Emil

    2012-01-01

    We describe two cases of recurrent erythema multiforme, both associated to infection with herpes simplex virus. The importance of subclinical herpes is illustrated. Antiviral and additional treatment is described.......We describe two cases of recurrent erythema multiforme, both associated to infection with herpes simplex virus. The importance of subclinical herpes is illustrated. Antiviral and additional treatment is described....

  16. An immunofluorescence test for diagnosis of ophthalmic herpes in a mouse corneal model Imunofluorescência para diagnóstico de herpes oftálmico usando como modelo córneas de camundongos infectados

    Directory of Open Access Journals (Sweden)

    Sílvia Regina Ferreira Gonçalves Pereira

    2007-04-01

    Full Text Available Herpes simplex virus type 1 (HSV-1 ophthalmic disease is the most common cause of corneal blindness in humans world-wide. Current culture techniques for HSV take several days and commercially available HSV laboratory based diagnostic techniques vary in sensitivity. Our study was conducted to evaluate the use of a quicker and simpler method to herpes ophthalmic diagnosis. Corneal smears were made by firm imprints of infected mouse eyes to glass slides, after smears were fixated with cold acetone, and an indirect immunofluorescence (IIF method was performed using monoclonal antibodies in a murine model of ophthalmic herpes. Eye swabs from infected mice were inoculated in Vero cells for virus isolation. Cytology and histology of the eye were also performed, using hematoxylin-eosin routine. Mouse eyes were examined by slit-lamp biomicroscopy for evidence of herpetic disease at various times postinoculation. We made a comparative evaluation of sensitivity, specificity and speed of methods for laboratory detection of HSV. Our results indicate that this IIF method is quick, sensitive, specific and can be useful in the diagnosis of ophthalmic herpes as demonstrated in an animal model.A doença oftálmica do vírus herpes simplex do tipo 1 (HSV-1 é a causa mais comum de cegueira córnea em humanos mundialmente. Técnicas de cultura atuais para HSV levam vários dias e laboratórios de HSV comercialmente disponíveis estabelecem que as técnicas diagnósticas variam em sensibilidade. Nosso estudo foi conduzido para avaliar a aplicação prática de um método mais rápido e simples para diagnosticar o herpes oftálmico. Decalques córneos foram feitos por impressões firmes de olhos de camundongos a lâminas de vidro, depois os decalques foram fixados com acetona fria, e um método de imunofluorescência indireta (IIF foi executado empregando anticorpos monoclonais no modelo murino de herpes oftálmico. Swabs de córnea foram inoculados em células Vero

  17. EPIDEMIOLOGY OF THE HERPES SIMPLEX VIRUS INFECTION

    Directory of Open Access Journals (Sweden)

    Ljiljana Kostadinović

    2002-07-01

    Full Text Available Over 150 sorts of viruses are capable of causing diseases of the respiratory ways. The virus infections have become the cost to be paid for urbanization and industrialization. The acute virus infections jeopardize mankind by their complications with numerous consequences. They open up the way to super infections, they provoke endogenous infections and lead to insufficiency of the vital organs. The viruses penetrate the organism mainly through the respiratory ways, digestive and urinary-sexual organs and skin. Some viruses immediately at the place of their entrance into the organism find receptive cells in which they can multiply (herpes virus and etc.. Some viruses must get through the blood, through the lymph or the nerve fibers to the target organs that they have affinity for.The changes that primarily occur in the mouth with manifest lymphadenopathy of the surrounding area emerge with respect to the type of the acute infection dis-ease.The human herpes viruses are responsible for a great number of diseases in people; that is why it can be said that the infections they induce are a very frequent cause of people's diseases in the world. Man is natural and the only host for the types I and II of the herpes simplex virus (HSV; that is why the infected person is regarded as the source of infection. The infection transmission can be by direct contact or over the contaminated secretions during the sexual intercourse. The age and the socioeconomic status (living conditions, level of medical culture, habits, etc. affect to agreat extent epidemiology of the HSV infection. The HSV distribution in the region of Niš in the five-year period (from 1987 to 1992 was the highest in the early and late summer (June and September.

  18. OBTENCIÓN DE ANTICUERPOS POLICLONALES IgY ANTIPARVOVIRUS CANINO A PARTIR DE YEMA DE HUEVO DE GALLINA

    Directory of Open Access Journals (Sweden)

    Pinto, J.

    2005-06-01

    Full Text Available Inmunizando un grupo de diez gallinas de postura raza Lohmann de 16 semanas de edad con parvovirus canino (CPV cepa vacunal, se obtuvieron anticuerpos IgY policlonales contra CPV en yema de huevo.En la extracción de los anticuerpos de la yema se requirieron dos pasos, el primero para la remoción de lípidos y el segundo para la precipitación de proteínas. Para la remoción de lípidos se usó el método PBS:Cloroformo y para la precipitación de los anticuerpos solubles (Inmunoglobulinas-IgY se usó el método de salting-out con sulfato de amonio ((NH42SO4. La evaluación del proceso se efectuó empleando el método comercial estándar “EGGstract IgY Purification System®” de PROMEGA.La metodología empleada permitió la obtención de anticuerpos IgY policlonales contra CPV a partir de yema de huevo de gallina en concentraciones altas por mililitro de yema, con una pureza aceptable y títulos altos; los resultados fueron comparables con el método comercial.

  19. Forebyggelse af herpes zoster med vaccination

    DEFF Research Database (Denmark)

    Kofoed, Kristian; Rønholt, Finn; Gerstoft, Jan

    2011-01-01

    Herpes zoster (HZ) and post-herpetic neuralgia (PHN) are frequently occurring diseases in elderly and in immuno-compromised persons. The live attenuated HZ vaccine boosts an existing immune response, so that the already established varicella-zoster virus infection is kept latent. Vaccination has...... been shown to halve the risk of HZ, and the risk of PHN is reduced by two thirds in people = 60 years. The vaccine is approved for persons aged = 50 years. However, the clinical efficacy of the vaccine is best studied in people aged = 60 years. The vaccine has so far not shown any serious side-effects....

  20. Managing recurrent genital herpes with acyclovir

    Directory of Open Access Journals (Sweden)

    Bedi T

    1995-01-01

    Full Text Available Seventy five patients of recurrent genital herpes (RGH treated with oral or topical acyclovir and placebo were compared and followed for periods ranging 4 to 8 years in a prospective study. Oral acyclovir definitely helps RGH patients; it shortens healing time; postpones recurrences and instills confidence in the patients. There is sufficient evidence that RGH dies a natural death with time as seen after 8 years follow up in placebo group patients. Topical use of acyclovir cream is not as useful as believed.

  1. Clasificación Histopatológica de Linfomas Caninos en la Casuística del Laboratorio de Patología Veterinaria de la Universidad Nacional Mayor de San Marcos (1996-2012)

    OpenAIRE

    Puicón N., Víctor; Laboratorio de Histología, Embriología y Patología Veterinaria, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima, Perú; Sandoval C., Nieves; Laboratorio de Histología, Embriología y Patología Animal, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima; Gouveia W., Danilo; Histopet - Laboratorio de Patología Veterinaria, São Paulo/SP, Brasil

    2014-01-01

    El presente estudio tuvo como objetivo emplear los criterios de la Organización Mundial de la Salud (OMS) en la clasificación histopatológica del linfoma canino en los casos diagnosticados en el laboratorio de patología veterinaria de la Universidad Nacional Mayor de San Marcos, Lima, Perú, entre 1996 y 2012. Se revisaron 1778 informes con diagnóstico histopatológico de neoplasias caninas y se encontraron 16 casos con diagnóstico histopatológico de linfoma canino. Se identificaron los siguien...

  2. Un problema tipo bin-packing

    Directory of Open Access Journals (Sweden)

    Geovanni Figueroa Mata

    2011-09-01

    Full Text Available Se presentan dos algoritmos heurísticos para resolver un problema de tipo binpacking en el cual se quiere guardar objetos de n tipos diferentes (en donde la demanda del objeto de tipo i-ésimo está dada por d1 en m tipos de recipientes con capacidades no necesariamente iguales; todos los recipientes de tipo j =1,2,...,m deben tener la misma distribución de los objetos. El objetivo es minimizar el costo de los recipientes por utilizar, donde el costo de cada tipo de recipiente está dado por wj (j =1,2,...,m. Para cada recipiente de tipo j =1,2,...,m se deben encontrar el número de repeticiones xj del recipiente, así como el número de copias aij del objeto i-ésimo que se deben almacenar en el recipiente j-ésimo (j =1,2,...,m.

  3. [Disseminated herpes zoster in diabetes mellitus].

    Science.gov (United States)

    Graue, N; Grabbe, S; Dissemond, J

    2006-02-24

    A 71-year old man presented with painful hemorrhagic vesicles and papules over the entire body that had persisted for three days. Type 2 diabetes mellitus type 2 had been diagnosed 20 years ago and had not been treated for the last 5 years. Therapy had been discontinued by the patient. HbA1c (11,9%) and blood glucose levels (up to 360 mg/dl) were abnormal. Varicella-zoster-DNA was replicated by PCR from the vesicle fluid. After the clinical diagnosis of disseminated herpes zoster had been confirmed systemic therapy with aciclovir 10 mg/kg day was started. There was no evidence of malignancy. Insulin therapy was initiated. Dissemination is a rare complication of herpes zoster, aided by immunosuppression. In the presented case there was no evidence of malignancy or other cause of immunosuppression, but the patient also had type 2 diabetes with very high blood glucose levels. The diabetes was thought to be causally related to the ineffective immune response to varicella zoster virus. There has been no previous published report of this relationship.

  4. Antiviral agents for herpes simplex virus.

    Science.gov (United States)

    Vere Hodge, R Anthony; Field, Hugh J

    2013-01-01

    This review starts with a brief description of herpes simplex virus types 1 and 2 (HSV-1 and HSV-2), the clinical diseases they cause, and the continuing clinical need for antiviral chemotherapy. A historical overview describes the progress from the early, rather toxic antivirals to acyclovir (ACV) which led the way for its prodrug, valacyclovir, to penciclovir and its prodrug, famciclovir (FCV). These compounds have been the mainstay of HSV therapy for two decades and have established a remarkable safety record. This review focuses on these compounds, the preclinical studies which reveal potentially important differences, the clinical trials, and the clinical experience through two decades. Some possible areas for further investigation are suggested. The focus shifts to new approaches and novel compounds, in particular, the combination of ACV with hydrocortisone, known as ME609 or zovirax duo, an HSV helicase-primase inhibitor, pritelivir (AIC316), and CMX001, the cidofovir prodrug for treating resistant HSV infection in immunocompromised patients. Letermovir has established that the human cytomegalovirus terminase enzyme is a valid target and that similar compounds could be sought for HSV. We discuss the difficulties facing the progression of new compounds. In our concluding remarks, we summarize the present situation including a discussion on the reclassification of FCV from prescription-only to pharmacist-controlled for herpes labialis in New Zealand in 2010; should this be repeated more widely? We conclude that HSV research is emerging from a quiescent phase. © 2013 Elsevier Inc. All rights reserved.

  5. Determinación de los niveles de colesterol Ldl comparando el método precipitado vs la fórmula de friedewald en caninos

    Directory of Open Access Journals (Sweden)

    J.H. Osorio

    2015-01-01

    Full Text Available e l objetivo del presente estudio fue comparar el método de precipitación con el método de fórmula de Friedewald para la determinación de colesterol L d L en caninos. Para ello, se tomaron muestras de sangre de 185 caninos adultos en estado de ayuno de diferente raza y sexo. s e determinaron los niveles de colesterol L d L mediante el método precipitado y pos - teriormente con el método de Friedewald. Los resultados fueron analizados estadísticamente mediante an O va de una vía. e l método precipitado reportó valores en mg/dl de: 52,40 promedio; 2,66 mínimo; 132,67 máximo; 130,01 rango y 24,29 de desviación estándar. Por su parte, ;;; y los valores del método de Friedewald en mg/dl fueron: 65,19 promedio; 4,55 mínimo; 184,20 máximo; 179,65 rango y 31,51 de desviación estándar. e l valor de p en el test F fue menor a 0.05, indicando diferencia estadísticamente significativa entre los dos métodos analizados con un nivel de confianza del 95,0%. e n conclusión se recomienda utilizar el método precipitado para la determinación de los niveles de colesterol L d L en caninos.

  6. Encefalite neo-natal pelo vírus do Herpes simplex: diagnóstico imuno-histoquímico de um caso

    Directory of Open Access Journals (Sweden)

    Isabel Lamego

    1993-09-01

    Full Text Available Os autores relatam o caso de recém-nascido do sexo feminino com crises convulsivas e lesões vesiculosas no nariz e lábio inferior, desde o quinto dia de vida. O exame do LCR mostrou alterações compatíveis a encefalite. Houve deterioração do quadro neurológico e respiratório, com morte da paciente. A autópsia parcial do crânio revelou cérebro edemaciado com área necro-hemorrágica envolvendo ambos os lobos temporais. O exame histopatológico revelou encefalite necro-hemorrágica, sem a presença de inclusões intranucleares. O exame imuno-histoquímico, realizado pela técnica da avidina-biotina-peroxidase utilizando anticorpos policlonais contra vírus Herpes simplex tipo 1 e tipo 2, mostrou-se positivo em numerosas células neuronais, astrocíticas e, principalmente, oligodendrogliais para o anticorpo contra o vírus Herpes simplex tipo 2.

  7. Erupción dentaria: estudio radiográfico de corredores de erupción de caninos superiores en niños con 10 años de edad.

    Directory of Open Access Journals (Sweden)

    Fernando Aguilera Zurira

    2014-12-01

    Full Text Available Las características anatómicas del canino superior lo convierten en el diente con mayor potencial de supervivencia en la arcada. Desde un punto de vista funcional, los caninos son considerados dientes claves en la oclusión. Con un gran protagonismo estético, dan armonía al frente anterior y la línea de la sonrisa. La erupción de los caninos superiores debe ser observada con frecuencia ya que es el diente en segundo lugar que presenta alteraciones en su erupción después de los terceros molares, este seguimiento se debe realizar con observaciones clínicas como radiográficas para tener la posibilidad de ir guiando el trayecto de erupción. Desde los 8 a 10 años de edad empieza a palparse la prominencia del canino en el fondo del vestíbulo. Si no se palpa a los 10 años, está indicado realizar un estudio radiológico para valorar la posición y reabsorción radicular del canino temporal. En este trabajo se realizó un estudio descriptivo en radiografías panorámicas en niños con 10 años de edad de ambos sexos de la ciudad de Quito, con el objetivo de analizar los corredores de erupción de caninos superiores, así como observar e interpretar la situación de los caninos superiores y su relación con las estructuras vecinas, describir las curvas y columnas de erupción en caninos superiores, para determinar si existe alteraciones y diferencias en cuanto a la erupción de los caninos definitivos en relación al sexo de los niños evaluados. La muestra estuvo constituida por 60 niños (30 hombres y 30 mujeres. De este grupo en cuanto a corredores de erupción se estableció que un 12% corresponde a curvas entrelazadas y un 7% a interrumpidas, estableciendo que el control clínico es fundamental y el seguimiento radiográfico secuencial permitirá ir revisando la evolución de la erupción de los caninos superiores y estructuras adyacentes. En cuanto a las columnas de erupción se determinó que el 2% de la muestra se encuentra en la

  8. Enfoque quirúrgico de canino incluido en el paladar: Reporte de un caso y revisión dela literatura

    Directory of Open Access Journals (Sweden)

    Adel Martínez Martínez

    2013-10-01

    Full Text Available ResumenLa inclusión dental hace referencia a la anomalía en la cual el diente pierde la fuerza de erupción y se encuentra sumergido en el maxilar con o sin patología asociada. El diente que más frecuentemente queda retenido después de los terceros molares mandibulares es el canino maxilar con una prevalencia que oscila entre el 1- 2.2 % dependiendo de la población evaluada. El diagnóstico de un canino incluido en el maxilar se realiza mediante evaluación clínica que incluye la inspección y palpación además del examen radiográfico periapical y panorámico. Varias opciones de tratamiento se pueden aconsejar al paciente desde el tratamiento interceptivo, la remoción quirúrgica del canino retenido, la exposición quirúrgica y tracción ortodóntica, el trasplante hasta el tratamiento no activo y observación, valorando las características individuales tanto del paciente como de la situación e inclinación del diente. A continuación se realiza una revisión bibliográfica seguida del reporte de caso clínico de un canino retenido en paladar en un paciente masculino de 27 años de edad donde esta indicada la extracción quirúrgica. (Duazary 2009 I; 56-61AbstractDental inclusion is when the tooth has lost the forcing eruption and is submerge in the maxilla with or any pathology. Maxillary canine are the most frecuently impacted teeth after the third molar with a prevalence ranging from 1 to 2•2% depending on the population examined. The diagnosis of an impacted maxillary canine is based through clinical evaluation that includes inspection, palpation and radiographic examination that involve taking periapical and orthopantomograph radiographs. Patient counseling on the various treatment options, from the interceptive treatment, the surgical remove of the ectopic canine, the surgical exposure and orthodontic alignment, the transplantation until the no active treatment and observation. We carried out a bibliographical revision

  9. Mastocitoma dérmico canino grado i para educación médica histológica

    OpenAIRE

    Acero Mondragón, Edwar; Maldonado Arango, María Inés

    2010-01-01

    Las descripciones histológicas de los mastocitos, en los textos de histología usados en educación médica, unánimemente refieren formas celulares ovales, con gránulos citoplasmáticos azules solo visibles con histoquímica metacromática y supravital de Azul de Toluidina, de Trypan o Rojo Neutro. No hay descripciones con hematoxilina y eosina dada la solubilidad de dichos gránulos en fijadores acuosos. Se reporta cómo los mastocitomas dérmicos caninos grado uno, son fuentes de mastocitos para la...

  10. Exodoncia de diente supernumerario, canino en transposición y enucleación de odontoma complejo: Reporte de Caso

    OpenAIRE

    Perea Paz, Miguel; Facultad de Estomatología, Universidad Peruana Cayetano Heredia. Lima,; Aliaga Del Castillo, Rosalinda; Facultad de Estomatología, Universidad Peruana Cayetano Heredia. Lima,; Aliaga Del Castillo, Arón; Facultad de Estomatología, Universidad Peruana Cayetano Heredia. Lima,

    2014-01-01

    Las anomalías dentarias más frecuentes e importantes que afectan a los niños son la presencia de piezas supernumerarias, piezas retenidas y odontomas. Algunos dientes retenidos se pueden encontrar en  transposición. Reportamos el caso de una paciente de sexo femenino de 11 años de edad con presencia de diente supernumerario, canino en transposición y odontoma complejo situados en la hemiarcada derecha del maxilar superior. El motivo de consulta fue por la presencia de dientes anteriores sobre...

  11. Parámetros fisiológicos en caninos pre y post competencia de Agility en Bogotá, Colombia

    Directory of Open Access Journals (Sweden)

    Jorge Hernando Forero López

    2006-12-01

    Full Text Available El estudio se llevó a cabo en la ciudad de Bogotá, ubicada a una altura media 2600 msnm, con temperatura promedio de 14°C. Se realizó un muestreo en el Polideportivo el Salitre y otro en el parque central de Modelia. El objetivo principal fue monitorear y estandarizar los cambios fisiológicos que se presentan en caninos atletas, como respuesta al ejercicio realizado en pruebas de Agility. Se muestrearon 15 caninos hembras de diferentes razas practicantes del Agility, de las escuelas Atalanta y X-treme Dog. El control se obtuvo de individuos en reposo, previo al ejercicio, inmediatamente a su llegada al área de investigación, donde se situaron las pistas para el entrenamiento, que incluía la toma de temperatura rectal, frecuencia de pulso, frecuencia respiratoria y de sangre arterial (arteria femoral. La muestra arterial se procesó con analizador sanguíneo portátil, obteniendo de hematocrito, hemoglobina, sodio, potasio, cloruro, nitrógeno uréico (BUN, glucosa, lactato, pH sanguíneo, presión de dióxido de carbono (PCO2, presión de oxígeno (PO2, bicarbonato, tensión de dióxido de carbono(TCO2, saturación de oxígeno (SO2, exceso de base (BE, anion gap y osmolalidad. Luego se inició el entrenamiento, simulando una competencia real, donde cada canino pasó cuatro veces por pista, y al final se monitorearon, siguiendo el procedimiento descrito para el control. Se compararon los resultados pre y post ejercicio, presentándose: aumento para temperatura, frecuencia respiratoria, pulso, pH, hematocrito, hemoglobina, sodio, cloro y osmolalidad (p<0,001; incremento en los valores de potasio, lactato y glucosa (p<0,01; ascenso para PO2, SO2 y BUN (p<0,05; descenso para PCO2, TCO2, BE y Anión Gap (p<0,001. Se concluye que los caninos deportistas en Bogotá presentan hipertermia, taquicardia, hipocapnia, alcalosis respiratoria acompañada de una acidosis metabólica compensatoria y hemoconcentración por una deshidratación clasificada

  12. ESTUDIO RADIOLÓGICO SOBRE LA FRECUENCIA DE PRESENTACIÓN DE DISPLASIA DE CADERA EN CANINOS DE LA RAZA LABRADOR RETRIEVER.

    OpenAIRE

    Tong G., Juan; Practica privada; Fernández A., Víctor; Clinica de Animales Menores, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima.; Mendoza A., Jorge; Universidad Católica de Chile; Díaz C., Diego; Clinica de Animales Menores, Facultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos, Lima.

    2014-01-01

    El presente trabajo es un estudio radiológico que evalúa la presencia de displasia de cadera (D.C. ó D.C.F.) en las articulaciones coxofemorales de caninos de la raza Labrador Retriever. Este estudio ha sido desarrollado según los lineamientos científicos requeridos por la Federación Cinológica Internacional (FCI) para asuntos concernientes a dicha enfermedad, que rigen en la mayoría de países, incluyendo Perú. Los ejemplares fueron evaluados en la Clínica de Animales Menores de la Facultad d...

  13. Construcción de una base de datos electrocardiográfica para caninos residentes en Bogotá, con apoyo ecocardiográfico

    OpenAIRE

    Ortega, Mauricio; Gómez, Leonardo; Cerquera, Alexander; Gutiérrez, Rafael

    2006-01-01

    El siguiente trabajo presenta la base de datos VETUAN_I, de medidas obtenidas en datos de reseña, electrocardiogramas y ecocardiogramas correspondientes a pacientes caninos sin deficiencias cardiacas evaluados en la Clínica Veterinaria .Veteriland. de la ciudad de Bogotá, mediante la utilización de equipos de diagnóstico de la Universidad Antonio Nariño. Esta base de datos está constituida por los parámetros o medidas cardiacas más utilizadas y por otros adicionales, lo cual permite comparar,...

  14. El meloxicam no modifica la disposición de la cefalexina en caninos Meloxicam does not modify cefalexin disposition in dogs

    OpenAIRE

    A. P Prados; V Kreil; L Tarragona; P Quaine; A Monfrinotti; M Rebuelto

    2008-01-01

    El objetivo de este estudio fue caracterizar la farmacocinética de la cefalexina administrada por vía intravenosa a caninos y determinar si la administración conjunta con meloxicam produce modificaciones en la misma. Se trabajó con 7 perros Beagle sanos. Las drogas administradas fueron cefalexina y meloxicam a dosis única de 25 mg/kg intravenosa y 0.1 mg/kg intravenosa respectivamente. Cada animal recibió cefalexina sola (experiencia 1) y cefalexina 5 minutos luego de la administración de mel...

  15. Retração rápida de caninos associada ao levantamento do seio maxilar Rapid canine retraction associated with maxillary sinus lifting

    Directory of Open Access Journals (Sweden)

    Paulo Renato Carvalho Ribeiro

    2007-10-01

    Full Text Available INTRODUÇÃO: a retração rápida de caninos por distração do ligamento periodontal é uma técnica de movimentação dentária que permite o fechamento de espaço da extração de primeiros pré-molares em um intervalo de 2 ou 3 semanas, proporcionando uma redução significativa no tempo do tratamento ortodôntico. A técnica cirúrgica para realização deste procedimento é relativamente simples, entretanto, nos casos onde o seio maxilar apresenta-se próximo ao ápice radicular de caninos e pré-molares, sempre há o risco de perfuração da membrana desta cavidade. OBJETIVO: o objetivo deste artigo é apresentar, através de um caso clínico, uma modificação na técnica original proposta por Liou e Huang, onde o levantamento do seio maxilar, executado de forma bastante simples, imprimiu maior controle e segurança ao ato cirúrgico necessário para a realização da retração rápida de caninos. CONCLUSÃO: a retração rápida de caninos é um procedimento exeqüível e o levantamento de seio maxilar pode auxiliar na execução do movimento dentário.INTRODUCTION: Rapid canine distalization using distraction of the periodontal ligament is a tooth movement technique that allows to close the space of extraction of first premolars in about 2 or 3 weeks, reducing orthodontic treatment time considerably. The surgical technique for this procedure is reasonably simple, however, during surgery in the maxilla, always exists the risk of sinus injury when the sinus membrane is close to the apex of canines and first premolars. AIM: The aim of this study is to present a case report showing a modification of the original technique proposed by Liou and Huang, where the maxillary sinus membrane lifting procedure was undertaken in a simple way, leaving it intact, and permitting a safer and more controlled protocol to start the rapid canine retraction. CONCLUSION: Rapid canine retraction is a viable procedure and maxillary sinus lifting may be

  16. Aislamiento e identificación bioquímica de microorganismos bacterianos a partir de infecciones de piel en caninos

    OpenAIRE

    Iovana Castellanos L.; Germán Rodríguez M.; Rosario Santos A.

    2011-01-01

    Las dermatitis bacterianas o piodermas en caninos son ocasionadas por microorganismos patógenos, de los cuales el Staphylococcus intermedius es el más frecuente. Los tratamientos empíricos de este grupo de enfermedades permiten la proliferación de cepas resistentes de importancia en salud pública como es el caso del S. aureus. De igual forma, el riesgo de zoonosis reversa a partir de mascotas portadoras de cepas resistentes crea un serio problema de salud pública que requiere vigilancia epide...

  17. Criopreservação de sêmen canino com um diluidor à base de água de coco

    OpenAIRE

    Cardoso,Rita de Cássia Soares; Silva,Alexandre Rodrigues; Uchoa,Daniel Couto; Silva,Lúcia Daniel Machado da

    2002-01-01

    A estocagem do sêmen por um longo período, permitindo o seu posterior uso representa uma importante ferramenta para criadores que desejam resguardar o potencial genético de seus reprodutores. O objetivo do presente trabalho foi avaliar o efeito da água de coco, gema de ovo e glicerol sobre o resfriamento e a criopreservação de sêmen canino. A fração espermática do ejaculado de 12 cães foi avaliada macro e microscopicamente e, em seguida, dividida em quatro alíquotas, submetidas à congelação e...

  18. Variaciones e índice simétrico de las variables cinéticas de caninos normales en el trote

    Directory of Open Access Journals (Sweden)

    Sergio Andrés Arias Serrato

    2012-12-01

    Full Text Available Los índices de simetría en la marcha de caninos han sido escasamente reportados. Falta consenso y se desconoce el efecto de la normalización en los resultados, sobre todo en la ortogonal craneocaudal. La cinética de la marcha en el ciclo de trote de quince perros mestizos se analizó mediante una plataforma de fuerza amplificada buscando determinar la simetría en la marcha. Se determinó el índice de simetría (IS bajo dos sistemas de normalización de los datos en caninos entonces: normalización por el peso corporal y normalización por las características morfométricas bidimensionales de los miembros. Se obtuvieron variables dinámicas primarias de estudio como el IS en el tiempo e impulso hasta el pico de fuerza y otras variables secundarias como resultado de la amplificación de la plataforma de fuerza. Los valores para cada ensayo se utilizaron para calcular media, desviación estándar y coeficiente de variación entre individuos y entre los animales. Las variables en la ortogonal craneocaudal fueron más irregulares y asimétricas que en la ortogonal vertical y tuvieron una menor correlación con la normalización por la masa corporal. La normalización por el peso corporal mostró una mayor eficacia que la normalización por las características morfométricas bidimensionales de los miembros ratificándose su uso en estudios de cinética en caninos. Se determinó que los índices de simetría no deben ser inferiores a 0,90 y 0,75 en las ortogonales vertical y craneocaudal respectivamente. Valores superiores a los descritos son valores aceptables para caninos normales y sin alteraciones ortopédicas.

  19. Herpes simplex encephalitis with thalamic, brainstem and cerebellar involvement.

    Science.gov (United States)

    Garg, Meenal; Kulkarni, Shilpa; Udwadia Hegde, Anaita

    2017-01-01

    Herpes simplex virus encephalitis is a common and treatable cause of acute encephalitis in all age groups. Certain radiological features such as temporal parenchymal involvement facilitate the diagnosis. The use of herpes simplex virus polymerase chain reaction has expanded the clinical and imaging spectrum. We report the case of a young patient who presented with a movement disorder and predominant involvement of thalami, brainstem and cerebellum on magnetic resonance imaging, and was diagnosed with herpes simplex virus encephalitis. Differentiation from Japanese encephalitis may be difficult in these patients, especially in endemic areas, and may necessitate the use of relevant investigations in all patients.

  20. Neodesarrollismo y el tipo de cambio competitivo

    National Research Council Canada - National Science Library

    Alejandro Fiorito; Nahuel Guaita; Silvio Guaita

    2015-01-01

      En este trabajo se intenta mostrar que las modificaciones en los tipos de cambio tienen efectos limitados en el aumento del producto, mientras que, inversamente, esos cambios impactan especialmente...

  1. Obtención de anticuerpos policlonales IgY antiparvovirus canino y evaluación en un sistema de aglutinación con látex

    Directory of Open Access Journals (Sweden)

    Jannet González-Figueredo

    2015-12-01

    Full Text Available La parvovirosis canina es una de las principales infecciones que provoca gastroenteritis, fundamentalmente en cachorros, con altos índices de morbiletalidad. Los diagnosticadores más utilizados se basan en la detección de partículas virales excretadas durante la fase aguda de la enfermedad. Algunos requieren equipos especializados, lo que aumenta los costos y el tiempo de diagnóstico. Por esto, la simplificación de estos métodos con alta sensibilidad y especificidad es prioritaria. En Cuba solo se logra un diagnóstico presuntivo sin la completa confirmación de la enfermedad, principalmente por la escasez o ausencia de un medio diagnóstico en toda la red de consultorios y clínicas veterinarias, rápido, eficaz y ajustable a nuestras condiciones. Este trabajo tuvo como objetivo obtener anticuerpos policlonales IgY a partir de yema de huevo de gallina y evaluarlos mediante un sistema de látex-aglutinación, para su posible uso como terapia y principalmente en el diagnóstico. Se inmunizaron por vía intramuscular dos gallinas de raza Leghorn con una cepa atenuada de parvovirus canino (PVC tipo 2. Se aplicaron 8 inoculaciones por ave cada 15 días. Se cosecharon los huevos y se purificaron los anticuerpos por el método de sulfato de dextrana/sulfato de sodio. Se determinó el título de IgY anti-PVC por el método de Inhibición de la Hemoaglutinación (IH y con antígeno de PVC acoplado a partículas de látex de poliestireno. Por IH se obtuvo un título de IgY anti-PVC de 1:1024. Las mezclas de anticuerpos con títulos alto y medio de ambas gallinas aglutinaron con los reactivos preparados con 230 y 460 µg/mL de antígeno. La mayor intensidad de la reacción y la mejor detectabilidad correspondieron a los reactivos elaborados con los anticuerpos de mayor título.

  2. Neodesarrollismo y el tipo de cambio competitivo

    OpenAIRE

    Alejandro Fiorito; Nahuel Guaita; Silvio Guaita

    2015-01-01

    En este trabajo se intenta mostrar que las modificaciones en los tipos de cambio tienen efectos limitados en el aumento del producto, mientras que, inversamente, esos cambios impactan especialmente en la distribución del ingreso al incidir en los precios domésticos. Se analizan y muestran múltiples referencias de la literatura internacional que cuestionan este "consenso de tipos de cambio competitivos". Se realizan correlaciones que muestran resultados distintos de los obtenidos en Rodrik (20...

  3. Reabsorción radicular de incisivos laterales superiores en relación con la erupción ectópica de caninos: Presentación de dos casos Maxillary incisor root resorption in relation to the ectopic canine: a report of two cases

    OpenAIRE

    F.J. Rodríguez Romero; M. Rodríguez Sánchez; B. Rodríguez Rodríguez

    2008-01-01

    La impactación del canino superior permanente es un problema clínico que puede provocar una serie de secuelas que van desde la perdida de espacio en el arco para su correcta erupción, hasta la reabsorción radicular de dientes vecinos. El presente articulo describe dos casos de pacientes con ausencia clínica de caninos superiores, produciendo reabsorción radicular de los incisivos laterales. Además se describen diferentes características relacionadas con la retención de caninos y se sugieren m...

  4. [The lysate and recombinant antigens in ELISA-test-systems for diagnostic of herpes simplex].

    Science.gov (United States)

    Ganova, L A; Kovtoniuk, G V; Korshun, L N; Kiseleva, E K; Tereshchenko, M I; Vudmaska, M I; Moĭsa, L N; Shevchuk, V A; Spivak, N Ia

    2014-08-01

    The lysate and recombinant antigens of various production included informula of ELISA-test-systems were analyzed. The ELISA-test-systems are used for detection of IgG to Herpes simplex virus type I and II. For testing the panel of serums PTH 201 (BBI Inc.) were used. The samples of this panel contain antibodies to Herpes simplex virus type I and II in mixed titers. The 69 serums of donors were used too (17 samples had IgG to Herpes simplex virus type I, 23 samples to Herpes simplex virus type II and 29 samples had no antibodies to Herpes simplex virus). The diagnostic capacity of mixture of recombinant antigens gG1 Herpes simplex virus type I and gG2 Herpes simplex virus type II (The research-and-production complex "DiaprofMed") was comparable with mixture of lysate antigen Herpes simplex virus type I and II (Membrane) EIE Antigen ("Virion Ltd."). In the test-systems for differentiation of IgG to Herpes simplex virus type I the recombinant antigen gG1 Herpes simplex virus type I proved to be comparable with commercial analogue Herpes simplex virus-1 gG1M ("Viral Therapeutics Inc."'). At the same time, capacity to detect IgG to Herpes simplex virus type II in recombinant protein gG2 Herpes simplex virus type II is significantly higher than in its analogue Herpes simplex virus-2 gG2c ("Viral Therapeutics Inc.").

  5. Etileno glicol na criopreservação de sêmen canino Ethylene glycol on canine semen cryopreservaton

    Directory of Open Access Journals (Sweden)

    Marcio Pereira Soares

    2002-08-01

    Full Text Available O objetivo deste trabalho foi avaliar a utilização do etileno glicol, adicionado ao meio Tris-gema, na criopreservação de sêmen canino, considerando os seus efeitos sobre a motilidade, o vigor e a morfologia espermática pré e pós-congelamento. Como doadores, utilizaram-se quatro cães da raça Pastor Alemão coletados por manipulação digital os quais no ejaculado apresentaram padrões mínimos de 90% de motilidade, cinco de vigor espermático (0 - 5 e no máximo 35% de defeitos morfológicos totais. As concentrações de etileno glicol testadas foram de 0, 25; 0,5 e 1,0M, sendo empregados como controle 0,8M de glicerol. Foram feitas cinco avaliações de motilidade e vigor, respectivamente, na obtenção da fração rica, depois da primeira diluição, ao atingir 4°C, após uma hora de estabilização a 4°C e no descongelamento. Avaliou-se a morfologia espermática em sêmen a fresco e após o descongelamento das amostras de cada tratamento. Não houve diferença na motilidade e na morfologia espermática dos grupos após o descongelamento. No vigor espermático pós- descongelamento, as concentrações de 0,25 e 0,5M de etileno glicol foram semelhantes entre si e com a concentração de 0,8M de glicerol (controle, mas diferiram da concentração de 1M, a qual apresentou vigor inferior ao controle. Conclui-se que, para a criopreservação de sêmen canino, o glicerol 0,8M pode ser substituído pelo etileno glicol nas concentrações de 0,25, 0,5 e 1,0M.The objective of the present work was to evaluate the efficiency of ethylene glycol on criopreservation of canine semen, considering its possible deleterious effects upon semen motility, vigor and morphology at the pre and post freezing stages, using a tris-egg yolk extender. Four adult german shepards were used as donors. Samples were obtained by digital manipulation, and only ejaculates presenting a minimum of 90% motility and 5 (0-5 vigor and no more than 35% of total morphological

  6. Potencial antiviral da quercetina sobre o parvovírus canino Antiviral potencial of quercetin in canine parvovirus

    Directory of Open Access Journals (Sweden)

    O.V. Carvalho

    2013-04-01

    Full Text Available Avaliou-se o efeito do flavonoide quercetina na replicação do parvovírus canino in vitro por meio do ensaio de determinação da atividade virucida (ensaio 1, ensaio de determinação da atividade sobre a célula (ensaio 2 e ensaio de tempo de adição das drogas em diferentes etapas do ciclo replicativo viral (ensaio 3. A quercetina apresentou significante atividade antiviral, com valores máximos de redução do título viral de 96,3% no ensaio 1, 90% no ensaio 2 e 90% no ensaio 3. Os efeitos mais expressivos ocorreram nas etapas de adsorção e penetração viral. Os resultados deste trabalho sugerem a importância da quercetina para a medicina veterinária.The in vitro effect of the flavonoid quercetin against canine parvovirus was evaluated. The antiviral activity of quercetin was evaluated by determining the virucidal activity (assay 1, determining the activity on the cell (assay 2 and using the time of addition assay to test the inhibition of the viral replication cycle (assay 3. Quercetin showed a significant antiviral activity, with maximum viral titer reduction of 96.3% in assay 1, 90% in assay 2 and 90% in assay 3. The most expressive effects occurred in the stages of viral adsorption and penetration. The results show the importance of quercetin for veterinary medicine.

  7. Patient and Physician Partnerships in Managing Genital Herpes

    National Research Council Canada - National Science Library

    Linda Alexander; Barbara Naisbett

    2002-01-01

    Genital herpes simplex virus infections are widespread throughout the world and are characterized by stigma, myth, and anxiety by patients and the public but are perceived as trivial by most physicians...

  8. Reactivation of herpes simplex virus-1 following epilepsy surgery

    Directory of Open Access Journals (Sweden)

    Sérgio Monteiro de Almeida

    2015-01-01

    Conclusion: The authors stress the potential risk of reactivation of HSV encephalitis after intracranial surgery. Herpes simplex virus encephalitis must be considered in neurosurgical patients who develop postoperative seizures and fever.

  9. Fatal Neonatal Herpes Simplex Infection Likely from Unrecognized Breast Lesions.

    Science.gov (United States)

    Field, Scott S

    2016-02-01

    Type 1 herpes simplex virus (HSV-1) is very prevalent yet in rare circumstances can lead to fatal neonatal disease. Genital acquisition of type 2 HSV is the usual mode for neonatal herpes, but HSV-1 transmission by genital or extragenital means may result in greater mortality rates. A very rare scenario is presented in which the mode of transmission was likely through breast lesions. The lesions were seen by nurses as well as the lactation consultant and obstetrician in the hospital after delivery of the affected baby but not recognized as possibly being caused by herpes. The baby died 9 days after birth with hepatic failure and disseminated intravascular coagulation. Peripartum health care workers need to be aware of potential nongenital (including from the breast[s]) neonatal herpes acquisition, which can be lethal. © The Author(s) 2015.

  10. Herpes zoster on segmental vitiligo: Wolf’s isotopic response?

    Directory of Open Access Journals (Sweden)

    Mankesh Lal Gambhir

    2014-04-01

    Full Text Available “Wolf’s isotopic response” describes the occurrence of a new skin disorder at the site of another, unrelated and already healed skin disease. In most cases of isotopic response, the initial dermatosis is herpes zoster, herpes simplex, varicella, thrombophlebitis, scrofuloderma and striae distense. The most frequent second dermatoses are granulomatous reactions, particularly granuloma annulare, and lichenoid diseases. Various etiological reasons including viral, immunologic, neural and vascular have been put forth. We report here a case in which the second disease was herpes zoster that appeared over the same dermatomes of pre-existing segmental vitiligo. The occurrence of vitiligo as first and herpes zoster as second disease in the “Wolf’s isotopic response” has not, to the best of our knowledge, been reported previously.

  11. Viruses Avian influenza, bovine herpes, bovine viral diarrhea virus ...

    Indian Academy of Sciences (India)

    ... human cytomegalovirus, herpes simplex virus, human immunodeficiency virus I, influenza, lymphocytic choriomeningitis virus, measles, papilloma, rabies, respiratory syncitial virus, simian immunodeficiency virus, simian virus 40. Bacteria Borrelia burgdorferi (Lyme disease), Moraxella bovis, Mycobacterium tuberculosis, ...

  12. [Laboratory diagnosis of genital herpes--direct immunofluorescence method].

    Science.gov (United States)

    Majewska, Anna; Romejko-Wolniewicz, Ewa; Zareba-Szczudlik, Julia; Kilijańczyk, Marek; Gajewska, Małgorzata; Młynarczyk, Grazyna

    2013-07-01

    Aim of the study was to determine clinical usefulness of direct immunofluorescence method in the laboratory diagnosis of genital herpes in women. Overall 187 anogenital swabs were collected from 120 women. Using a dacron-tipped applicator 83 swabs were collected from women suspected of genital herpes and 104 from patients with no signs of genital infection. All samples were tested using cell culture (Vero cell line) and then direct immunofluorescence method (DIF) for the identification of antigens of herpes simplex viruses: HSV-1 and HSV-2. Characteristic cytopathic effect (CPE), indicative of alphaherpesvirus infection, was observed in 43.4% of cultures with clinical specimens collected from women with suspected genital herpes and in 29.8% of cultures of clinical specimens taken from patients with no clinical symptoms of genital herpes. Herpes simplex viruses were determined in 73 samples by direct immunofluorescence method after amplification of the virus in cell culture. The DIF test confirmed the diagnosis based on the microscopic CPE observation in 85%. In 15% of samples (taken from pregnant women without clinical signs of infection) we reported positive immunofluorescence in the absence of CPE. The frequency of antigen detection was statistically significantly higher in samples that were positive by culture study (chi-square test with Yates's correction, p genital herpes in swabs taken from the vestibule of the vagina and the vulva. However, there was no statistically significant difference in the frequency of detection of Herpes Simplex Virus antigens in specimens from different parts of the genital tract in both groups of women (chi-square test, p > 0.05). In our study HHV-1 was the main causative agent of genital herpes. The growing worldwide prevalence of genital herpes, challenges with the clinical diagnosis, and availability of effective antiviral therapy are the main reasons for a growing interest in rapid, proper laboratory diagnosis of infected

  13. Chronic Ulcerative Herpes Simplex Virus Infection of the Vulva

    OpenAIRE

    Kelly Griffith-Bauer; Mary O’Hearn; Benjamin D. Ehst

    2012-01-01

    Herpes simplex virus infections in HIV-infected individuals can be clinically unusual and difficult to treat due to underlying problems with cell-mediated immunity and the occurrence of antiviral resistance. Additionally, partial or incomplete restoration of immune function may result in chronic ulcerations that require rotational treatments. In this report, we describe the case of a 38-year-old HIV-positive woman who developed the ulcerative form of chronic herpes simplex infection despite h...

  14. Genital herpes and its treatment in relation to preterm delivery.

    Science.gov (United States)

    Li, De-Kun; Raebel, Marsha A; Cheetham, T Craig; Hansen, Craig; Avalos, Lyndsay; Chen, Hong; Davis, Robert

    2014-12-01

    To examine the risks of genital herpes and antiherpes treatment during pregnancy in relation to preterm delivery (PTD), we conducted a multicenter, member-based cohort study within 4 Kaiser Permanente regions: northern and southern California, Colorado, and Georgia. The study included 662,913 mother-newborn pairs from 1997 to 2010. Pregnant women were classified into 3 groups based on genital herpes diagnosis and treatment: genital herpes without treatment, genital herpes with antiherpes treatment, and no herpes diagnosis or treatment (unexposed controls). After controlling for potential confounders, we found that compared with being unexposed, having untreated genital herpes during first or second trimester was associated with more than double the risk of PTD (odds ratio (OR) = 2.23, 95% confidence interval (CI): 1.80, 2.76). The association was stronger for PTD due to premature rupture of membrane (OR = 3.57, 95% CI: 2.53, 5.06) and for early PTD (≤35 weeks gestation) (OR = 2.87, 95% CI: 2.22, 3.71). In contrast, undergoing antiherpes treatment during pregnancy was associated with a lower risk of PTD compared with not being treated, and the PTD risk was similar to that observed in the unexposed controls (OR = 1.11, 95% CI: 0.89, 1.38). The present study revealed increased risk of PTD associated with genital herpes infection if left untreated and a potential benefit of antiherpes medications in mitigating the effect of genital herpes infection on the risk of PTD. © The Author 2014. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  15. Localized Eruptive Blue Nevi after Herpes Zoster

    Directory of Open Access Journals (Sweden)

    Fany Colson

    2016-05-01

    Full Text Available A 52-year-old White man presented with a dozen small, well-restricted, punctiform, asymptomatic, blue-gray macules on the left shoulder. A few months earlier, he had been treated with oral acyclovir for herpes zoster (HZ affecting the left C7–C8 dermatomes. All the blue macules appeared over a short period of time and then remained stable. The patient had not experienced any previous trauma or had tattooing in this anatomical region. The clinical diagnosis suggested blue nevi. Dermatoscopy revealed small, well-limited, dark-blue, compact, homogeneous areas evoking dermal blue nevi. An excisional biopsy was performed and the histological examination confirmed a blue nevus. As far as we are aware of, this is the first report of eruptive blue nevi following HZ, and it should be included in the differential diagnosis of zosteriform dermatoses responding to an isotopic pathway. In addition, a brief review concerning eruptive nevi is presented.

  16. Prótesis coxofemoral en caninos: reacción tisular y métodos de evaluación radiográfica

    Directory of Open Access Journals (Sweden)

    Sergio Andrés Arias Serrato

    2008-06-01

    Full Text Available El uso de prótesis coxofemorales en el canino viene constituyendo una de las técnicas más utilizadas y eficientes en el tratamiento de pacientes con displasia coxofemoral. Las complicaciones consecuentes de su uso son generalmente diagnosticadas mediante la ayuda de la radiología y radican en los materiales utilizados y la reacción de los tejidos hacia el implante. La remodelación ósea, osteoporosis, las fracturas y el desprendimiento aséptico son las reacciones tisulares más comúnmente encontradas en los pacientes sometidos a la técnica quirúrgica. En este trabajo son revisadas las diferentes manifestaciones radiológicas de caninos hacia los implantes coxofemorales y el método de evaluación radiográfico en el postoperatorio de pacientes implantados con la prótesis coxofemoral.

  17. Infecção pelo Parvovírus Canino em filhotes com gastrenterite em Niterói, Rio de Janeiro, Brasil de 1995 a 1997

    Directory of Open Access Journals (Sweden)

    Rita de Cássia Nasser Cubel Garcia

    2000-01-01

    Full Text Available Amostras fecais de cães com gastrenterite, até 6 meses de idade, foram testadas para a presença do parvovírus canino (CPV-2 pela reação de hemaglutinação (HA e confirmadas pela reação de inibição da hemaglutinação (HI. Quarenta das 79 amostras, recebidas no período de abril de 1995 a junho de 1997, foram consideradas positivas. Aproximadamente 70% destas amostras foram obtidas de animais entre 2 e 4 meses de idade, época em que o risco de contraírem a infecção pelo CPV-2 é alto apesar da vacinação. Nenhuma variação sazonal da infecção pelo parvovírus canino pôde ser observada, e um estudo retrospectivo realizado na PolVet - UFF mostrou que em um período de 6 anos (1991-97, casos de gastrenterite ocorreram durante todos os anos em Niterói, sem uma sazonalidade definida.

  18. Neonatal herpes in Serbia: Is it a problem or not?

    Directory of Open Access Journals (Sweden)

    Knežević Aleksandra

    2014-01-01

    Full Text Available With 20-80% mortality, neonatal infection caused by herpes simplex virus (HSV or neonatal herpes is among the most severe of all perinatal infections. The majority of neonatal HSV infections are acquired during delivery, although in utero and postnatal infections do occur. Primary maternal infection is associated with a high rate of transmission (~50%, compared to <3% in infants of women with reactivated disease. Other factors that influence transmission include HSV type, premature delivery, etc. Clinical manifestations have been classified into three forms: skin-eye-mouth disease, CNS and disseminated disease. The diagnosis of neonatal HSV infection includes the detection of HSV DNA by PCR in samples from neonate and mother. The incidence of neonatal herpes differs widely between different countries. In Serbia, the data about neonatal herpes incidence are scarce. The results of our pilot study showed that the minimal estimation of the national incidence of neonatal herpes is 7.5 per 100 000. Therefore, the set up and implementation of a national neonatal herpes surveillance system might provide valuable information for the accurate assessment of disease burden and development of an effective prevention strategy in Serbia. [Projekat Ministarstva nauke Republike Srbije, br. 175073

  19. Original papers Herpes simplex virus infection – survey on knowledge of herpes virus infection among people aged 18–35

    Directory of Open Access Journals (Sweden)

    Ewelina Biało-Wójcicka

    2015-03-01

    Full Text Available Introduction . Genital herpes is one of the most common sexually transmitted viral diseases and the most common cause of mucous membrane ulcerations in the genital area. The number of sexually transmitted infections caused by herpes virus (HSV, especially by HSV-1, is increasing. In the Polish population, there are no precise and current epidemiological data on herpes virus infections, especially in the anogenital area. A major problem concerns HSV infections in pregnancy, which are connected with the risk of in-utero and perinatal virus transmission. Herpes simplex virus infection in pregnancy threatens the life and health of an infant. Objective . To obtain information regarding the occurrence of herpes simplex in people of reproductive age as well as the assessment of knowledge on HSV infection and transmission, especially in pregnancy. Material and methods. Two hundred people (133 women and 67 men aged 18–35 years, attending a dermatological clinic in the first half of 2014 with typical dermatological diseases, took part in the study. The subjects filled in the questionnaire including information on age, occurrence of erosions, scabs in the facial and genital area, diagnosis of oral and genital herpes virus infection, information given by the medical staff on the herpes infection, treatment with oral antivirus drugs, danger of herpes infection in pregnancy and risk of transmission of the HSV virus to fetuses and newborns. Results . Among the 200 people who took part in the study, 27% indicated the occurrence of herpes or recurring lesions in the form of vesicles and scabs on the border of skin and mucous membranes; in 1.5% of them genital herpes was diagnosed. Only 12% of investigated persons were treated with antiviral medicines. Sixty-eight percent of subjects stated that HSV is an infectious disease, 16% claimed that it is non-infectious, and a similar number did not know if it is an infectious disease or not. Only half of the studied

  20. Miocardite chagásica em caninos no Estado do Rio Grande do Sul Chagasic myocarditis in dogs in Rio Grande do Sul

    Directory of Open Access Journals (Sweden)

    Saulo Petinatti Pavarini

    2009-07-01

    Full Text Available Neste trabalho, são relatados dois casos de morte súbita por doença de Chagas aguda em caninos da zona rural de Porto Alegre, Rio Grande do Sul, Brasil. Os cães, um macho Pit Bull com nove meses (canino 1 e uma fêmea Labrador Retriever com dois anos (canino 2, morreram em janeiro de 2005 e maio de 2008, respectivamente. As necropsias revelaram aumento cardíaco em ambos os casos. O coração do canino 2 apresentou formato globoso com múltiplas áreas pálidas na musculatura cardíaca, mais evidentes no ventrículo direito e câmaras cardíacas dilatadas, principalmente as da direita. Ao exame histológico, ambos os casos apresentaram alterações semelhantes caracterizadas por infiltrado inflamatório difuso não-purulento acentuado, predominantemente linfocitário intersticial. Nas fibras miocárdicas, havia grande número de pseudocistos, repletos de formas amastigotas do Trypanosoma cruzi. Ao teste sorológico TESA-blot, amostra do canino 2 foi positiva para anticorpos IgM e IgG anti-T.cruzi, achado característico da fase aguda da miocardite chagásica. Os resultados indicam que a doença de Chagas deve ser investigada em casos de morte súbita em cães na região Sul do Brasil e que a espécie pode servir como reservatório e sentinela da doença em humanos.Acute Chagas disease caused sudden death in two dogs from Porto Alegre rural zone of, Rio Grande do Sul, southern Brazil. A 9-month-old Pit Bull male (dog 1 and a 2-year-old Labrador Retriever female (dog 2 died in January 2005 and May 2008, respectively. At necropsy, the hearts were enlarged. In dog 2, heart was remarkably globoid with multiple pale areas scattered in the myocardium, especially in the right ventricle. Heart chambers, especially in the right side, were dilated. Histological findings were similar in both cases and consisted of diffuse non suppurative myocarditis predominantly with lymphocytic interstitial infiltrates. Within myocardial fibers were observed

  1. Pesquisa do vírus herpes simples na saliva de pacientes com paralisia facial periférica de Bell Herpes simplex virus in the saliva of peripheral Bell’s palsy patients

    Directory of Open Access Journals (Sweden)

    Paulo Roberto Lazarini

    2006-02-01

    Full Text Available Os primeiros herpes-vírus a serem descritos foram os tipos 1 e 2, cuja denominação é herpes simplex 1 e 2 ou HSV-1 e HSV-2. Estes vírus possuem características biológicas particulares, tais como a capacidade de causar diferentes tipos de doenças, assim como estabelecer infecções latentes ou persistentes por toda a vida dos hospedeiros e de serem reativados causando lesões que podem se localizar no sítio da infecção primária inicial ou próxima a ele. Postula-se que a reativação deste vírus no gânglio geniculado esteja relacionada com a paralisia de Bell. Nesta situação, os vírus, que estariam latentes neste gânglio, sofreriam reativação e replicação difundindo-se pelo nervo facial e seus ramos, dentre eles o nervo corda do tímpano, que ao estimular a secreção salivar possibilitaria a identificação do DNA viral na saliva dos pacientes. Até recentemente, um grande número de pacientes eram diagnosticados como portadores de uma forma desta paralisia, chamada de idiopática ou de paralisia de Bell. Com o advento da técnica de estudo do DNA viral pelo método da reação da polimerase em cadeia (PCR, diversos autores encontraram DNA do vírus herpes simplex tipo I no líquido cefalorraquidiano, na secreção lacrimal, na saliva e nos gânglios geniculados de pacientes com paralisia de Bell. OBJETIVO: observar a prevalência do vírus herpes simplex tipo I pela técnica de PCR, na saliva de pacientes com PFP de Bell, relacionando-a com a evolução clínica destes casos. METODOLOGIA: Avaliamos 38 pacientes portadores de Paralisia Facial Periférica de Bell, que foram submetidos a anamnese, exame médico geral e otorrinolaringológico e coleta de saliva para detecção do DNA viral pela técnica de PCR. O grupo controle correspondeu a 10 adultos normais. RESULTADOS: Obtivemos positividade para o DNA viral em 11 casos dos 38 avaliados, o que corresponde a 29% da amostra. Este resultado foi estatisticamente significante

  2. Estrutura temporal dos tipos de xuro

    OpenAIRE

    Reboredo Nogueira, Juan Carlos

    2013-01-01

    Esta unidade didáctica forma parte do curso de Análise Económica dos Mercados Financeiros I que se imparte no primeiro cuadrimestre do Máster en Economía: Organización Industrial e Mercados Financeiros. Esta unidade ten como obxectivo analizar a estrutura temporal dos tipos de xuro, é dicir a relación existente entre os tipos de xuro a diferentes prazos. En particular, estudarase a curva cupón cero, a súa utilidade no proceso de valoración dos activos financeiros e os diferentes mé...

  3. Algunos tipos de preferencias no transitivas

    Directory of Open Access Journals (Sweden)

    Carmen Vázquez

    2010-01-01

    Full Text Available Este trabajo ofrece una visión sobre la modelación de las relaciones de preferencias del consumidor diferente a la clásica, pues prescindimos de la hipótesis de transitividad. Concretamente, analizamos dos tipos de relaciones de preferencias no transitivas, las acíclicas y las asimétricas, que bajo ciertas condiciones, admiten tipos de representación numérica distintos. Justificamos la aceptación de las mismas mediante ejemplos prácticos y vemos también resultados que garantizan la existencia de representaciones continuas de estas relaciones de preferencias.

  4. Increased density of cutaneous nerve fibres in the affected dermatomes after herpes zoster therapy

    National Research Council Canada - National Science Library

    Zografakis, Charalampos; Tiniakos, Dina G; Palaiologou, Marina; Kouloukoussa, Mirsini; Kittas, Christos; Staurianeas, Nikos

    2014-01-01

    Herpes zoster neural injury was assessed by determining cutaneous nerve density in skin biopsies from the affected dermatomes of 35 adult patients with herpes zoster in the acute phase and 3 months...

  5. Pediatric herpes simplex virus infections: an evidence-based approach to treatment.

    Science.gov (United States)

    Sanders, Jennifer E; Garcia, Sylvia E

    2014-01-01

    Herpes simplex virus is a common virus that causes a variety of clinical presentations ranging from mild to life-threatening. Orolabial and genital herpes are common disorders that can often be managed in an outpatient setting; however, some patients do present to the emergency department with those conditions, and emergency clinicians should be aware of possible complications in the pediatric population. Neonatal herpes is a rare disorder, but prompt recognition and initiation of antiviral therapy is imperative, as the morbidity and mortality of the disease is high. Herpes encephalitis is an emergency that also requires a high index of suspicion to diagnose. Herpes simplex virus is also responsible for a variety of other clinical presentations, including herpes gladiatorum, herpetic whitlow, eczema herpeticum, and ocular herpes. This issue reviews the common clinical presentations of the herpes simplex virus, the life-threatening infections that require expedient identification and management, and recommended treatment regimens.

  6. [Dutch Institute for Health Care Improvement revised guideline, 'Sexually transmitted diseases and neonatal herpes'

    NARCIS (Netherlands)

    Bleker, O.P.; Meijden, W.I. van der; Wittenberg, J.; Bergen, J.E. van; Boeke, A.J.; Doornum, G.J.J. van; Henquet, C.J.; Galama, J.M.D.; Postma, M.J.; Prins, J.M.; Voorst Vader, P.C. van

    2003-01-01

    The Dutch Institute for Health Care Improvement revised guideline, 'Sexually transmitted diseases and neonatal herpes' summarises the current scientific position on the diagnosis and treatment of a great number of sexually transmitted diseases (STD) and neonatal herpes. Symptomatic treatment of

  7. Update on Neonatal Herpes Simplex Epidemiology in the Netherlands: A Health Problem of Increasing Concern?

    NARCIS (Netherlands)

    van Oeffelen, Louise; Biekram, Manisha; Poeran, Jashvant; Hukkelhoven, Chantal; Galjaard, Sander; van der Meijden, Wim; Op de Coul, Eline

    2018-01-01

    This paper provides an update on the incidence of neonatal herpes, guideline adherence by health care professionals (HCP), and trends in genital herpes simplex virus (HSV) infection during pregnancy in the Netherlands.

  8. Genital Herpes - Initial Visits to Physicians' Offices, United States, 1966-2012

    Science.gov (United States)

    ... Data & Statistics Sexually Transmitted Diseases Figure 48. Genital Herpes — Initial Visits to Physicians’ Offices, United States, 1966 – ... page . NOTE : The relative standard errors for genital herpes estimates of more than 100,000 range from ...

  9. Clinical Efficacy of Oral Ganciclovir for Prophylaxis and Treatment of Recurrent Herpes Simplex Keratitis

    National Research Council Canada - National Science Library

    Xin Wang Linnong Wang Nianlang Wu Xinjun Ma Jianjiang Xu

    2015-01-01

    Background:Herpes simplex keratitis (HSK) caused by herpes simplex virus 1 (HSV-1),which has high recurrent rate and incidence of severe vision loss,is the leading cause of infectious blindness...

  10. Encefalite herpética disseminada: apresentação de um caso autopsiado com estudo imuno-histoquímico

    Directory of Open Access Journals (Sweden)

    José Eymard Homem Pittella

    1989-12-01

    Full Text Available Relata-se um caso autopsiado de encefalite herpética disseminada em criança de um ano e três meses. O paciente era sadio até a moléstia atual quando apresentou febre, crises convulsivas repetidas e alterações de consciência que progrediram para o coma, evoluindo ao óbito em oito dias. O quadro neuropatológico era caracterizado por necrose e inflamação em focos múltiplos disseminados nos hemisférios cerebrais, tronco encefálico e cerebelo. A técnica da Avidina-Biotina-Peroxidase revelou, em neurônios do tálamo, imunor-reatividade intra-citoplasmática e muito raramente intranuclear para antígeno do herpes-vírus tipo 1. Este caso difere dos demais de encefalite herpética descritos na literatura em dois aspectos: (1 pela disseminação das lesões, em contraste com as formas limitadas topograficamente ao sistema límbico e, menos comumente, ao tronco encefálico; (2 pela presença de necrose, inflamação e hemorragias focais, alterações estas praticamente ausentes nos casos de encefalite disseminada tipicamente descritos em indivíduos imunodeprimidos.

  11. Mastocitoma cutâneo canino: estudo de 45 casos Canine cutaneous mast cell tumor: study of 45 cases

    Directory of Open Access Journals (Sweden)

    R.R. Rech

    2004-08-01

    Full Text Available Quarenta e cinco mastocitomas cutâneos caninos foram graduados histologicamente com o uso de hematoxilina-eosina. Foram empregados os métodos azul de toluidina e região organizadora nucleolar argirofílica (AgNOR para, respectivamente, evidenciar os grânulos citoplasmáticos e avaliar o índice de proliferação celular. Diversas características histológicas foram observadas, como distribuição das células na pele, tamanho, forma, aspecto de citoplasma e núcleo, quantidade de estroma, presença de eosinófilos e alterações associadas. Com base nessas caracteríscas, 37,8% dos mastocitomas foram classificados como grau I, 51,1% como grau II e 11,1% como grau III. A média geral de AgNOR nos mastocitomas foi de 1,9 (1,2 a 4,3 e as médias para os graus I, II e III foram, respectivamente, de 1,5, 1,85 e 3,25. A técnica de AgNOR mostrou ser de fácil execução, custo acessível e confiável como meio auxiliar para estimar um prognóstico mais objetivo para os mastocitomas.Forty-five cutaneous canine mast cell tumors were graded histologically on haematoxylin and eosin-stained sections. Toluidine blue and AgNOR methods were employed to enhance the intracytoplasmic granules and to assess cell proliferation, respectively. From these 45 samples histological features were observed as cell distribution, size, shape, nuclear and cytoplasmic appearance, amount of stroma, presence of eosinophils and some associated changes. Based on those features, 37.8% of the mast cell tumors were classified as grade I, 51.1% as grade II and 11.1% as grade III. General AgNOR mean value was 1.9 (range 1.2-4.3 whereas the means for grades I, II and III were, respectively, 1.2, 1.85 and 3.25. The AgNOR method proved to be feasible, inexpensive and a reliable tool to predict a more accurate prognosis for mast cell tumors.

  12. Latent Herpes Viruses Reactivation in Astronauts

    Science.gov (United States)

    Mehta, Satish K.; Pierson, Duane L.

    2008-01-01

    Space flight has many adverse effects on human physiology. Changes in multiple systems, including the cardiovascular, musculoskeletal, neurovestibular, endocrine, and immune systems have occurred (12, 32, 38, 39). Alterations in drug pharmacokinetics and pharmacodynamics (12), nutritional needs (31), renal stone formation (40), and microbial flora (2) have also been reported. Evidence suggests that the magnitude of some changes may increase with time in space. A variety of changes in immunity have been reported during both short (.16 days) and long (>30 days) space missions. However, it is difficult to determine the medical significance of these immunological changes in astronauts. Astronauts are in excellent health and in superb physical condition. Illnesses in astronauts during space flight are not common, are generally mild, and rarely affect mission objectives. In an attempt to clarify this issue, we identified the latent herpes viruses as medically important indicators of the effects of space flight on immunity. This chapter demonstrates that space flight leads to asymptomatic reactivation of latent herpes viruses, and proposes that this results from marked changes in neuroendocrine function and immunity caused by the inherent stressfullness of human space flight. Astronauts experience uniquely stressful environments during space flight. Potential stressors include confinement in an unfamiliar, crowded environment, isolation, separation from family, anxiety, fear, sleep deprivation, psychosocial issues, physical exertion, noise, variable acceleration forces, increased radiation, and others. Many of these are intermittent and variable in duration and intensity, but variable gravity forces (including transitions from launch acceleration to microgravity and from microgravity to planetary gravity) and variable radiation levels are part of each mission and contribute to a stressful environment that cannot be duplicated on Earth. Radiation outside the Earth

  13. The negative association between a history of recurrent herpes labialis and cervical neoplasia

    NARCIS (Netherlands)

    Burger, M. P.; Wilterdink, J. B.

    1988-01-01

    We considered the possibility that herpetic recurrences and herpes virus associated neoplasia are mutually exclusive disorders because they are expressions of different herpes virus-host relationships. We assumed that the human body copes with orofacial and genital herpes infections in the same

  14. Herpes zoster, immunological deterioration and disease progression in HIV-1 infection

    NARCIS (Netherlands)

    Veenstra, J.; Krol, A.; van Praag, R. M.; Frissen, P. H.; Schellekens, P. T.; Lange, J. M.; Coutinho, R. A.; van der Meer, J. T.

    1995-01-01

    OBJECTIVE: To study the incidence of herpes zoster, the relationship between herpes zoster and immunological markers, and the prognostic value of herpes zoster for progression of HIV disease. DESIGN AND METHODS: A total of 966 homosexual participants in The Amsterdam Cohort Study were studied.

  15. Papular (erosive) herpes genitalis. A clinical variant in sarcoid and pregnancy.

    Science.gov (United States)

    Young, A W; Frankel, M; Menegus, M

    1977-12-01

    A unique papular (erosive) variant of herpes genitalis is described in a patient with sarcoid and in 1 who was pregnant. The occurrence of this unique expression of herpes infection in two conditions associated with immunologic changes seems more than incidental. It is suggested that patients presenting with papular (erosive) herpes genitalis be studied for underlying immune deficiency.

  16. [Clinical, epidemiological, and etiological studies of adult aseptic meningitis: a report of 12 cases of herpes simplex meningitis, and a comparison with cases of herpes simplex encephalitis].

    Science.gov (United States)

    Himeno, Takahiro; Shiga, Yuji; Takeshima, Shinichi; Tachiyama, Keisuke; Kamimura, Teppei; Kono, Ryuhei; Takemaru, Makoto; Takeshita, Jun; Shimoe, Yutaka; Kuriyama, Masaru

    2018-01-26

    We treated 437 cases of adult aseptic meningitis and 12 cases (including 2 recurrent patients; age, 31.8 ± 8.9 years; 7 females) of herpes simplex meningitis from 2004 to 2016. The incidence rate of adult herpes simplex meningitis in the cases with aseptic meningitis was 2.7%. One patient was admitted during treatment of genital herpes, but no association was observed between genital herpes and herpes simplex meningitis in the other cases. The diagnoses were confirmed in all cases as the cerebrospinal fluid (CSF) was positive for herpes simplex virus (HSV)-DNA. For diagnosis confirmation, the DNA test was useful after 2-7 days following initial disease onset. Among other types of aseptic meningitis, the patients with herpes simplex meningitis showed relatively high white blood cell counts and relatively high CSF protein and high CSF cell counts. CSF cells showed mononuclear cell dominance from the initial stage of the disease. During same period, we also experienced 12 cases of herpes simplex encephalitis and 21 cases of non-hepatic acute limbic encephalitis. Notably, the patients with herpes simplex meningitis were younger and their CSF protein and cells counts were higher than those of the patients with herpes simplex encephalitis.

  17. Herpes Zoster in Healthy Children: A Retrospective Study

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    Birgül Tepe

    2016-06-01

    Full Text Available Objective: Herpes zoster is an acute dermatomal viral infection caused by the reactivation of varicella zoster virus. While it is commonly seen among elderly and immunocompromised individuals, it is rare in healthy children. The aim of this study was to evaluate the clinical features, treatment and complications of healthy children with herpes zoster. Methods: Thirty one patients aged between 0-16 years who were admitted to our clinic with the diagnosis of herpes zoster, between January 2014 and December 2014, were evaluated retrospectively for age, gender, month of admission, complaint, history of chickenpox infection or varicella vaccination, triggering factors, dermatomal involvement, complications and treatment. Results: Among 31 patients with diagnosis of herpes zoster, 19 were boys (61.3% and 12 were girls (38.7%. The mean of age was 9.12±4.4 years. Twenty patients had thoracic (64.5%, six had lumbar (19.4% and five had cervical involvements (16.2%. The most frequent symptoms were pruritus and pain, respectively. Six patients were administered topical treatment and 25 patients were treated with both systemic and topical treatments. Complication was not observed. Conclusion: Herpes zoster is also being encountered increasingly in healthy children nowadays. It is benign and generally no complications are observed. Incidence can vary because of geographic and socioeconomic differences like vaccination programs.

  18. Pityriasis Lichenoides Chronica Associated with Herpes Simplex Virus Type 2

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    Antonio Javier González Rodríguez

    2012-01-01

    Full Text Available Introduction. Pityriasis lichenoides is a rare, acquired spectrum of skin conditions of an unknown etiology. Case Report. A 28-year-old man presented with recurrent outbreaks of herpes simplex virus associated with the onset of red-to-brown maculopapules located predominantly in trunk in each recurrence. Positive serologies to herpes simplex virus type 2 were detected. Histopathological examination of one of the lesions was consistent with a diagnosis of pityriasis lichenoides chronica. Discussion. Pityriasis lichenoides is a rare cutaneous entity of an unknown cause which includes different clinical presentations. A number of infectious agents have been implicated based on the clustering of multiple outbreaks and elevated serum titers to specific pathogens (human immunodeficiency virus, cytomegalovirus, Epstein-Barr virus, Toxoplasma gondii, and herpes simplex virus. In our patient, resolution of cutaneous lesions coincided with the administration of antiviral drugs and clinical improvement in each genital herpes recurrence. In conclusion, we report a case in which cutaneous lesions of pityriasis lichenoides chronica and a herpes simplex virus-type 2-mediated disease have evolved concomitantly.

  19. Chronic Ulcerative Herpes Simplex Virus Infection of the Vulva

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    Kelly Griffith-Bauer

    2012-09-01

    Full Text Available Herpes simplex virus infections in HIV-infected individuals can be clinically unusual and difficult to treat due to underlying problems with cell-mediated immunity and the occurrence of antiviral resistance. Additionally, partial or incomplete restoration of immune function may result in chronic ulcerations that require rotational treatments. In this report, we describe the case of a 38-year-old HIV-positive woman who developed the ulcerative form of chronic herpes simplex infection despite highly active antiretroviral therapy and valacyclovir prophylaxis. Repeated intravenous courses of foscarnet and topical cidofovir finally controlled her erosions as her cell-mediated immunity was slowly restored. This case highlights the challenges that still exist in diagnosing and managing this rare presentation of herpes simplex virus

  20. Recurrent herpes zoster in a child with SLE

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    Jain C

    1995-01-01

    Full Text Available A 12-year-old girl had systemic lupus erythematosus (SLE and type IV lupus nephritis since three-and-a-half years. She was treated with prednisolone and cyclophosphamide. She had first attack of herpes zoster (HZ involving eighth and ninth thoracic segments on right side at the age of nine years. Second attack occurred on the same segments on same side at the age of twelve years. The second attack of herpes zoster was treated with oral acyclovir 400 mg five times a day for seven days plus analgesics and multi-vitamins. Most probably this is the first case of recurrent herpes zoster (RHZ in a child in Indian literature.

  1. Herpes Zoster Duplex Unilateralis: Two Cases and Brief Literature Review

    Science.gov (United States)

    Son, Jee Hee; Chung, Bo Young; Kim, Hye One; Cho, Hee Jin

    2016-01-01

    Cases involving dermatomal herpes zoster in two or more locations are rare, especially in immunocompetent patients. When two noncontiguous dermatomes are involved, if affected unilaterally, it is called herpes zoster duplex unilateralis; if bilaterally, bilateralis. Here, we report two cases of herpes zoster duplex unilateralis. A 66-year-old man presented with painful erythematous grouped vesicles on his left scalp, forehead, trunk, and back (left [Lt.] V1, Lt. T8). Histologic findings were consistent with herpetic infection. A 33-year-old woman presented with painful erythematous grouped vesicles and crust on her left forehead and neck (Lt. V1, Lt. C5). Both patients were treated with oral administration of famcyclovir 750 mg/day for seven days. PMID:27904277

  2. Herpes zoster infection of maxillary nerve: A case report

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    Isha Thakur

    2017-01-01

    Full Text Available Herpes zoster of the trigeminal nerve branches caused by varicella zoster is a clinical entity consisting of erythematous macules, papules, vesicles, bullae, small ulcers and erythematous plaques, with characteristic short acute/pre-eruptive phases and long herpetic periods with pain. It is caused by reactivation of latent varicella infection. Herpes zoster is a less common endemic disease compared to varicella. During the prodromal stage, the only presenting symptom may be odontalgia, which may prove to be a diagnostic challenge for the dentist. Emergency treatment for a misdiagnosis such as trigeminal neuralgia, odontalgia, and acute pulpitis, as well as complications reported in literature such as tooth resorption, periapical lesions, periodontal destructions, and osteomyelitis may cause an irreversible damage to the patient. Hence, the dentist must be familiar with the presenting signs and symptoms in prodrome of herpes zoster infection of trigeminal nerve. The present article focuses on the pathogenesis, clinical picture, difficulties in diagnosis and management of such cases.

  3. Herpes Zoster-Induced Ogilvie’s Syndrome

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    Irfan Masood

    2015-01-01

    Full Text Available Ogilvie’s syndrome due to herpes zoster infection is a rare manifestation of VZV reactivation. The onset of rash of herpes zoster and the symptoms of intestinal obstruction can occur at different time intervals posing a significant diagnostic challenge resulting in avoidable surgical interventions. Herein, we describe a case of 35-year-old male who presented with 6-day history of constipation and colicky abdominal pain along with an exquisitely tender and vesicular skin eruption involving the T8–T11 dermatome. Abdominal X-ray and ultrasound revealed generalized gaseous distention of the large intestine with air up to the rectum consistent with paralytic ileus. Colonoscopy did not show any obstructing lesion. A diagnosis of Ogilvie’s syndrome associated with herpes zoster was made. He was conservatively managed with nasogastric decompression, IV fluids, and acyclovir. The patient had an uneventful recovery and was later discharged.

  4. Herpes Simplex Mastitis: Case Report and Review of the Literature

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    Holly Brown

    1996-01-01

    Full Text Available The most common sites of herpes simplex virus (HSV infection are around the oral cavity and the genitalia. However, HSV can infect any skin or mucous membrane surface. One uncommon site of HSV infection is the breast. Reports of herpetic breast infections are predominantly cases of transmission from a systemically HSV-infected neonate to the mother during breast-feeding. A review of the literature identified only six reports suggesting HSV breast lesions acquired by means other than through an infected infant. Of these, only one report suggests HSV transmission to the breast from a male sexual partner. A second case of clinically unsuspected symptomatic herpes mastitis presumably acquired from sexual contact in a 46-year-old woman is presented. Herpes simplex type 1 was isolated by using polymerase chain reaction and restriction fragment length polymerization techniques. The purpose of this report is to alert physicians to HSV mastitis.

  5. The Laboratory Diagnosis of Herpes Simplex Virus Infections

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    Ameeta Singh

    2005-01-01

    Full Text Available Herpes simplex virus (HSV types 1 and 2 cause genital herpes infections and are the most common cause of genital ulcer disease in industrialized nations. Although these infections are very common, the majority of them remain underdiagnosed because they are asymptomatic or unrecognized. A clinical diagnosis of genital herpes should always be confirmed by laboratory testing; this can be accomplished through the use of direct tests for viral isolation, the detection of antigen or, more recently, the detection of HSV DNA using molecular diagnostic techniques. Testing for serotypes is recommended because of the different prognostic and counselling implications. Type-specific HSV serology is becoming more readily available and will enhance the ability to make the diagnosis and guide clinical management in select patients.

  6. Maturação e fecundação "in vitro" de ovócitos de caninos domésticos (Canis familiaris)

    OpenAIRE

    Berenice de Avila Rodrigues

    2003-01-01

    Este estudo foi realizado com o objetivo de 1) determinar a eficácia de duas temperaturas (370 C e 390 C) e três intervalos de tempo (48, 72 e 96h) comumente usados na maturação in vitro (MIV) de ovócitos caninos, 2) verificar o efeito de hormônios heterólogos: hormônio folículo estimulante (FSH) 0,5µg/ml, estradiol 20µg/ml e somatotropina humana (hST) 1µg/ml; e o efeito de proteínas: 0,4 % albumina sérica bovina (BSA), 10 % de soro de vaca em estro inativado (SVE), e 10 % soro de cadela em e...

  7. Estudio retrospectivo de masas cutáneas neoplásicas en caninos diagnosticadas histopatológicamente en la Universidad de La Salle (1999-2003)

    OpenAIRE

    Carlos Eduardo Aparicio Ortiz; Jorge Hernando Forero López

    2008-01-01

    El propósito del trabajo fue realizar un análisis retrospectivo de las neoplasias cutáneas en caninos diagnosticadas en la Universidad de La Salle, en Bogotá, en el período 1999-2003. El presente estudio se llevó a cabo con la información obtenida de los registros del área diagnóstica e histopatológica de la Universidad de La Salle. La información fue discriminada y analizada teniendo en cuenta las siguientes variables: diagnóstico, raza, sexo, edad, malignidad y localización del tumor. Los 1...

  8. Nonvirion Antigens Produced by Herpes Simplex Viruses 1 and 2

    Science.gov (United States)

    Tarro, Giulio; Sabin, Albert B.

    1973-01-01

    Of nine herpes simplex virus 1 strains (from lip, mouth, throat, cornea, or brain) only five produced enough nonvirion antigen (i.e., not a structural component of the virus) to be detected by complement fixation with specially prepared, virion-absorbed, type-1 guinea pig antisera, while the remaining four strains produced only enough of the same antigen to induce specific antibody in hyperimmunized guinea pigs. While the type 1 virion antiserum used reacted equally well by complement fixation with the type 1 and type 2 strains, the type 1 nonvirion antisera failed to react with nonvirion antigens produced by three type-2 (genital) strains. However, type 2 nonvirion antiserum reacted equally well with the three type 2 and four type 1 nonvirion antigens that were tested. It appears, therefore, that while herpes simplex virus 1 codes only for type 1 nonvirion antigen, herpes simplex 2 codes not only for an immunologically distinct type 2 nonvirion antigen but also for enough type 1 nonvirion antigen to stimulate antibody production for it. Herpes simplex 2 nonvirion antigen exhibited the same properties as type 1, i.e., its activity was lost on storage at 4° for 15 days, it was sedimented by centrifugation at 33,360 × g for 1 hr, and the maximum concentration was found at 3 hr in guinea pig kidney culture cells, but at 24 hr in HEp 2 and rabbit kidney culture cells. Sera from patients with genital lesions caused by herpes simplex virus 2, as well as from randomly selected adults, failed to react with either type 2 or type 1 nonvirion antigens. Accordingly, the basic information is now available to permit the use of these nonvirion antigens to determine the possible role of the herpes simplex viruses in certain human cancers. PMID:4352219

  9. MANEJO TERAPÉUTICO DE LA INTOXICACIÓN CON FLUORACETATO DE SODIO (GUAYAQUIL® EN CANINOS: REPORTE DE CINCO CASOS –2012-2013–

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    V. M. Molina

    2014-01-01

    Full Text Available El presente reporte relata el manejo terapéutico de la intoxicación con fluoracetato de sodio dispensado a cinco caninos en la Clínica Veterinaria de Antioquia, Medellín (Co-lombia, entre los años 2012 y 2013. Cinco pacientes caninos llegaron a consulta con cuadro neurológico, disforia y convulsiones, con una hora de evolución. Los animales entraron en contacto con el fluoracetato de sodio (rodenticida Guayaquil® por vía oral. Los pacientes fueron sometidos a un protocolo de manejo que incluyó canalización de vena cefálica externa a solución lactato de Ringer, así como control de las convulsio-nes con pentobarbital (10 mg/kg endovenoso como dosis inicial, después de lo cual fueron intubados. Recibieron además etanol (28%, 10 ml/kg diluidos en solución de Hartmann, gluconato de calcio (1 mg/kg en infusión y guayacolato de glicerilo (110 mg/kg, endovenoso lento. Los pacientes fueron evaluados respecto de sus constantes fisiológicas y estado neurológico según la escala Glasgow. Se mantuvo el protocolo cita-do hasta obtener ausencia de signos convulsivos, disforia y delirio. Los cinco pacientes sobrevivieron a la intoxicación y el promedio de recuperación fue de tres días. Aunque no se pudo determinar ocurrencia de secuelas neurológicas posteriores a la intoxicación, los pacientes recibieron control médico durante 15 días. El manejo oportuno del cuadro tóxico, con anticonvulsivantes, soluciones alcalinizantes, gluconato de calcio, guayacolato de glicerilo y etanol, demostraron ser efectivas como estrategias para el manejo de la intoxicación por fluoracetato de sodio.

  10. Comparación de los efectos cardiovasculares del propofol, tiopental y de la mezcla propofol-tiopental en un grupo de caninos sanos premedicados con hidromorfona

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    Camilo Padilla Peñuela

    2013-12-01

    Full Text Available El objetivo de la investigación fue determinar las diferencias en el desempeño cardiovascular de caninos sanos premedicados con hidromorfona e inducidos y mantenidos con tres diferentes protocolos anestésicos. Se evaluaron quince caninos sanos entre uno y seis años de edad, los cuales no presentaban afecciones cardiacas o que generaran dolor, y con un riesgo anestésico clasificado como ASA I. Los pacientes se distribuyeron en tres grupos y cada uno fue inducido y mantenido en un plano anestésico (estadio III, plano 2 con un protocolo según el grupo al que se habían incorporado (tiopental, propofol o la mezcla propofol-tiopental. En cada paciente se realizó ecocardiografía (fracción de acortamiento y fracción de eyección y se midió el lactato plasmático y la presión arterial por el método oscilométrico. Las mediciones se realizaron en tres periodos de tiempo diferentes (T1, antes de premedicar; T2, después de premedicar y T3, después de la inducción. Se observó una diferencia muy significativa en la frecuencia cardiaca de los pacientes anestesiados con propofol (p = 0,0004 con tendencia a la bradicardia, y la presión arterial se mostró disminuida en este grupo; sin embargo, la diferencia no logró ser significativa (p = 0,08. En cuanto a los demás parámetros (fracción de eyección, fracción de acortamiento y lactato tampoco se observaron diferencias.

  11. Criopreservação de sêmen canino com um diluidor à base de água de coco

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    Cardoso Rita de Cássia Soares

    2002-01-01

    Full Text Available A estocagem do sêmen por um longo período, permitindo o seu posterior uso representa uma importante ferramenta para criadores que desejam resguardar o potencial genético de seus reprodutores. O objetivo do presente trabalho foi avaliar o efeito da água de coco, gema de ovo e glicerol sobre o resfriamento e a criopreservação de sêmen canino. A fração espermática do ejaculado de 12 cães foi avaliada macro e microscopicamente e, em seguida, dividida em quatro alíquotas, submetidas à congelação em quatro diluidores, sendo todos à base água de coco e diferindo quanto à presença ou não da gema de ovo e glicerol. Durante o resfriamento, não se observou diferença entre os grupos, entretanto, após o congelamento e descongelamento, o diluidor adicionado de gema de ovo e glicerol (ACGG foi superior aos demais quanto à motilidade, vigor e morfologia espermática. Nesse grupo, os valores de motilidade (%, vigor (0-5 e alterações morfológicas totais (% após a descongelação foram 56,7 ± 16,1, 3,4 ± 0,5 e 23,8 ± 8,4, respectivamente. Diante dos resultados, concluiu-se que a adição de gema de ovo e glicerol ao diluidor foi necessária para a preservação da qualidade espermática após criopreservação de sêmen canino.

  12. Herpes genitalaren ikerketa epidemiologiko, kliniko eta mikrobiologikoa Bilbo hirian

    OpenAIRE

    Macho Aizpurua, Mikele

    2017-01-01

    224 p. El herpes genital (HG) es una de las infecciones de transmisión sexual (ITS) con mayordistribución en la población mundial con aproximadamente 500 millones de individuosafectados en todo el mundo. Además de presentar repercusiones físicas, psíquicas yeconómicas, el HG incrementa el riesgo de transmisión del virus de la inmunodeficienciahumana (VIH) y durante el embarazo es causa potencial del herpes neonatal. Debido a lastendencias sociales, demográficas y migratorias actuales, la p...

  13. Herpes Simplex Encephalitis Complicated by Cerebral Hemorrhage during Acyclovir Therapy.

    Science.gov (United States)

    Harada, Yukinori; Hara, Yuuta

    2017-01-01

    Herpes simplex encephalitis (HSE) can be complicated by adverse events in the acute phase. We herein present the case of a 71-year-old woman with HSE complicated by cerebral hemorrhage. She presented with acute deterioration of consciousness and fever and was diagnosed with HSE based on the detection of herpes simplex virus-1 in the cerebrospinal fluid by a polymerase chain reaction. The cerebral hemorrhage developed during acyclovir therapy; however, its diagnosis was delayed for 2 days. After the conservative treatment of the cerebral hemorrhage, the patient made a near-complete recovery. Cerebral hemorrhage should be considered as an acute-phase complication of HSE.

  14. Optimization of Herpes Virus Infection Treatment in Children

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    Yu.P. Kharchenko

    2012-03-01

    There was revealed the polymorphism of human herpes virus 6 in children associated with virus replication activity. The important role of chronic human herpes virus 6 in forming of sickly children group with involvement of nervous and cardiovascular systems and presence of the various clinical variants correlating with the form of an infection contamination is confirmed. Principles of stratification of patients, diagnostic and treatment approaches with account of clinical semiology and complex of molecular-genetic, serological, bacteriological, neurofunctional and cardiovascular examinations were developed. The treatment positive results allow to confirm the benefit from integrative multidisciplinary therapy.

  15. Cystic encephalomalacia and intrauterine herpes simplex virus infection.

    Science.gov (United States)

    Gray, P H; Tudehope, D I; Masel, J

    1992-01-01

    Cystic encephalomalacia occurred in two preterm infants who had proven intrauterine herpes simplex virus type 2 infection. Calcification was evident in the basal ganglia. Follow-up scans indicated that the cysts had resolved over a period of two months in one infant, while in the case of the other, the cysts became progressively larger with significant ventricular dilatation developing. While cystic changes in the brain of preterm infants are usually due to periventricular leukomalacia, intrauterine infection needs to be considered as a possible cause. Antiviral treatment may be of benefit to infants with herpes simplex virus infection.

  16. 2017 European guidelines for the management of genital herpes.

    Science.gov (United States)

    Patel, Rajul; Kennedy, Oliver J; Clarke, Emily; Geretti, Anna; Nilsen, Arvid; Lautenschlager, Stephan; Green, John; Donders, Gilbert; van der Meijden, Willem; Gomberg, Mikhail; Moi, Harald; Foley, Elizabeth

    2017-12-01

    Genital herpes is one of the commonest sexually transmitted infections worldwide. Using the best available evidence, this guideline recommends strategies for diagnosis, management, and follow-up of the condition as well as for minimising transmission. Early recognition and initiation of therapy is key and may reduce the duration of illness or avoid hospitalisation with complications, including urinary retention, meningism, or severe systemic illness. The guideline covers a range of common clinical scenarios, such as recurrent genital herpes, infection during pregnancy, and co-infection with human immunodeficiency virus.

  17. Increasing trends of herpes zoster in Australia.

    Directory of Open Access Journals (Sweden)

    Raina MacIntyre

    Full Text Available Increasing trends in incidence of herpes zoster (HZ have been reported in Australia and internationally. This may reflect the impact of childhood VZV vaccination programs introduced universally in Australia in late 2005. The objective of this study was to evaluate changes in incidence of HZ and PHN in Australia over time, and associated healthcare resource utilisation.Australian data on general practice (GP encounters for HZ, specific antiviral prescribing data from the pharmaceutical benefits scheme, emergency department presentations from the states of NSW and Victoria and national hospitalisation data for HZ were analysed for time trends using regression models. Two time periods (2000-2006 and 2006-2013 were compared which correspond broadly with the pre- and post- universal VZV vaccination period.All data sources showed increasing rates of HZ with age and over time. The GP database showed a significant annual increase in encounters for HZ of 2.5 per 100,000 between 1998 and 2013, and the rates of prescriptions for HZ increased by 4.2% per year between 2002 and 2012. In the 60+ population HZ incidence was estimated to increase from 11.9 to 15.4 per 1,000 persons using GP data or from 12.8 to 14.2 per 1,000 persons using prescription data (p<0.05, between the two periods. Hospitalisation data did not show the same increasing trend over time, except for the age group ≥80 years. Most emergency visits for HZ were not admitted, and showed significant increases over time.The burden of HZ in Australia is substantial, and continues to increase over time. This increase is seen both pre- and post-universal VZV vaccination in 2005, and is most prominent in the older population. The substantial burden of HZ, along with ageing of the Australian population and the importance of healthy ageing, warrants consideration of HZ vaccination for the elderly.

  18. Neodesarrollismo y el tipo de cambio competitivo

    Directory of Open Access Journals (Sweden)

    Alejandro Fiorito

    2015-01-01

    Full Text Available En este trabajo se intenta mostrar que las modificaciones en los tipos de cambio tienen efectos limitados en el aumento del producto, mientras que, inversamente, esos cambios impactan especialmente en la distribución del ingreso al incidir en los precios domésticos. Se analizan y muestran múltiples referencias de la literatura internacional que cuestionan este "consenso de tipos de cambio competitivos". Se realizan correlaciones que muestran resultados distintos de los obtenidos en Rodrik (2008 con los mismos datos utilizados, aunque simplemente cambiando la metodología de datos de panel y usando en cambio una más convencional de series de tiempo.

  19. Cold Sore, Cold Soul? An Examination of Orolabial Herpes in Film

    Directory of Open Access Journals (Sweden)

    Alex C. HOLLIDAY

    2016-04-01

    Full Text Available The sociocultural phenomenon of herpes is attributed to two strains of the herpes simplex virus: herpes simplex virus type 1 (HSV-1 causes orolabial cold sores while herpes simplex virus type 2 (HSV-2 is typically identified in genital lesions, though both viruses may cause clinically similar signs and symptoms anywhere in or on the body. While these infections are extremely prevalent and typically benign, media sources such as film have perpetuated a negative public perception of the disease. Thus, a large portion of society continues to associate these conditions with sexual misconduct and moral failing. Despite decades of available antiviral therapy to shorten and suppress outbreaks, movies continue to exploit herpes for degradation and for humor. Portrayal of genital herpes in films is avoided in order to avert unnecessary and grotesque nude scenes, so depictions of cold sores are preferred. This article analyzes the use of orolabial herpes lesions in selected English language films released from 1984-2012.

  20. Herpes Simplex Virus Infection Mimicking Bullous Disease in an Immunocompromised Patient

    Directory of Open Access Journals (Sweden)

    Anne L.Y. Lecluse

    2010-06-01

    Full Text Available Immunodeficient patients are at risk of developing extended or atypical herpes simplex virus infections, which can be easily misdiagnosed. We present the case of a 79-year-old, treatment-induced (oral corticosteroid, immunocompromised female with an extensive atypical herpes simplex virus infection. This patient presented with multiple erosions and vesicles on the trunk with a subacute onset. The clinical differential diagnosis was herpes simplex infection, herpes zoster infection, pemphigus vulgaris or bullous pemphigoid. Due to the atypical clinical presentation and negative Tzanck test, suspicion of viral infection was low. High-dose steroid treatment was initiated. Subsequent histopathology, however, showed a herpes simplex virus infection. After discontinuing steroid treatment and initiating antiviral treatment, the patient recovered within a week. Emphasis must be placed on the importance of clinical awareness of extended and clinically atypical herpes simplex infections in immunocompromised patients. A negative Tzanck test does not rule out the possibility of a herpes infection.

  1. Calcium spirulan derived from Spirulina platensis inhibits herpes simplex virus 1 attachment to human keratinocytes and protects against herpes labialis.

    Science.gov (United States)

    Mader, Julia; Gallo, Antonio; Schommartz, Tim; Handke, Wiebke; Nagel, Claus-Henning; Günther, Patrick; Brune, Wolfram; Reich, Kristian

    2016-01-01

    Chronic infections with herpes simplex virus (HSV) type 1 are highly prevalent in populations worldwide and cause recurrent oral lesions in up to 40% of infected subjects. We investigated the antiviral activity of a defined Spirulina platensis microalga extract and of purified calcium spirulan (Ca-SP), a sulfated polysaccharide contained therein. The inhibitory effects of HSV-1 were assessed by using a plaque reduction assay and quantitative PCR in a susceptible mammalian epithelial cell line and confirmed in human keratinocytes. Time-of-addition and attachment experiments and fluorescence detection of the HSV-1 tegument protein VP16 were used to analyze the mechanism of HSV-1 inhibition. Effects of Ca-SP on Kaposi sarcoma-associated herpesvirus/human herpes virus 8 replication and uptake of the ORF45 tegument protein were tested in human retinal pigment epithelial cells. In an observational trial the prophylactic effects of topically applied Ca-SP were compared with those of systemic and topical nucleoside analogues in 198 volunteers with recurrent herpes labialis receiving permanent lip makeup. Ca-SP inhibited HSV-1 infection in vitro with a potency at least comparable to that of acyclovir by blocking viral attachment and penetration into host cells. Ca-SP also inhibited entry of Kaposi sarcoma-associated herpesvirus/human herpes virus 8. In the clinical model of herpes exacerbation, the prophylactic effect of a Ca-SP and microalgae extract containing cream was superior to that of acyclovir cream. These data indicate a potential clinical use of Ca-SP containing Spirulina species extract for the prophylactic treatment of herpes labialis and suggest possible activity of Ca-SP against infections caused by other herpesviruses. Copyright © 2015 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

  2. Tipos e mitos do pensamento brasileiro

    Directory of Open Access Journals (Sweden)

    Ianni Octavio

    2002-01-01

    Full Text Available No pensamento brasileiro são freqüentes os "tipos ideais" elaborados por diferentes autores e que se tornam emblemáticos, notáveis ou mesmo definitivos, podendo, às vezes, figurar como mitos. Esse é o caso do bandeirante, do gaúcho, do Jeca Tatu, do Macunaíma, do homem cordial e outros. Vale a pena refletir sobre este aspecto da cultura e do pensamento brasileiros.

  3. Seroprevalencia de tres tipos de virus hepatotropos en población adolescente de la provincia de Guadalajara

    Directory of Open Access Journals (Sweden)

    Martínez Pérez José Antonio

    2001-01-01

    Full Text Available FUNDAMENTO: Las hepatitis virales son uno de los grupos de enfermedades infecciosas más frecuentes en patología humana y aunque la mayoría son benignas algunas pueden evolucionar hacia formas crónicas. El objetivo del estudio fue conocer la prevalencia de la infección por los virus de la hepatitis C, Epstein-Barr y herpesvirus humano tipo 6, en los escolares de 8º de EGB (13-14 años, y relacionarla con las variables sexo y el hábitat (rural o urbano en el que vivían. MÉTODOS: Estudio descriptivo de tipo transversal, en una muestra representativa de la población escolar de 8º de EGB de la provincia de Guadalajara en 1998-1999. Muestreo aleatorio sistemático estratificado según sexo y centro escolar (diseño muestral polietápico. Se determinó la tasa de anticuerpos específicos de la clase IgG, mediante técnica de ELISA. RESULTADOS: Se estudió a 268 escolares (46,6% varones. La prevalencia de anticuerpos frente al virus de Epstein-Barr fue de 73,5% (IC: 67,9%-78,5%; el 72% (IC: 64%-80% entre los varones y el 74,8% (IC: 67,7%-81,9% entre las mujeres (NS; el 65,6% (IC: 57,4%-73,8% vivían en medio urbano y el 80,7% (IC: 74,2%-87,2% en el rural (p<0,05. La prevalencia de positivos para el virus de la hepatitis C fue del 0,7% -dos personas, siendo ambas del sexo femenino y viviendo una en el medio urbano y otra en el rural-. Para el virus herpes tipo 6 la prevalencia fue del 82,4% (IC: 77,9%-86,9%, el 81,5% (IC: 74,7%-88,3% entre los varones y el 83,2% (IC: 77,1%-89,3% entre las mujeres (NS, el 86,7% (IC: 80,4%-92,2% vivían en medio urbano y el 78,5% (IC: 73,1%-86,5% en el rural (p<0,05. CONCLUSIONES: La prevalencia por los virus de Epstein-Barr y herpes humano tipo 6 y baja frente al VHC es elevada, lo cual concuerda con las características del medio y edad de las personas estudiadas.

  4. SEROPREVALENCIA DE TRES TIPOS DE VIRUS HEPATOTROPOS EN POBLACIÓN ADOLESCENTE DE LA PROVINCIA DE GUADALAJARA

    Directory of Open Access Journals (Sweden)

    José Antonio Martínez Pérez

    2001-01-01

    Full Text Available Fundamento. Las hepatitis virales son uno de los grupos de enfermedades infecciosas más frecuentes en patología humana y aunque la mayoría son benignas algunas pueden evolucionar hacia formas crónicas. El objetivo del estudio fue conocer la prevalencia de la infección por los virus de la hepatitis C, Epstein-Barr y herpesvirus humano tipo 6, en los escolares de 8.º de EGB (13-14 años, y relacionarla con las variables sexo y el hábitat (rural o urbano en el que vivían. Métodos. Estudio descriptivo de tipo transversal, en una muestra representativa de la población escolar de 8.º de EGB de la provincia de Guadalajara en 1998-1999. Muestreo aleatorio sistemático estratificado según sexo y centro escolar (diseño muestral polietápico. Se determinó la tasa de anticuerpos específicos de la clase IgG, mediante técnica de ELISA. Resultados. Se estudió a 268 escolares (46,6% varones. La prevalencia de anticuerpos frente al virus de Epstein-Barr fue de 73,5% (IC: 67,9%-78,5%; el 72% (IC: 64%-80% entre los varones y el 74,8% (IC: 67,7%-81,9% entre las mujeres (NS; el 65,6% (IC: 57,4%-73,8% vivían en medio urbano y el 80,7% (IC: 74,2%-87,2% en el rural (p < 0,05. La prevalencia de positivos para el virus de la hepatitis C fue del 0,7% -dos personas, siendo ambas del sexo femenino y viviendo una en el medio urbano y otra en el rural-. Para el virus herpes tipo 6 la prevalencia fue del 82,4% (IC: 77,9%-86,9%, el 81,5% (IC: 74,7%-88,3% entre los varones y el 83,2% (IC: 77,1%-89,3% entre las mujeres (NS, el 86,7% (IC: 80,4%-92,2% vivían en medio urbano y el 78,5% (IC: 73,1%-86,5% en el rural (p < 0,05. Conclusiones. La prevalencia por los virus de Epstein-Barr y herpes humano tipo 6 y baja frente al VHC es elevada, lo cual concuerda con las características del medio y edad de las personas estudiadas.

  5. Herpes neolabialis: herpes simplex virus type 1 infection of the neolabia in a transgender woman.

    Science.gov (United States)

    Elfering, Lian; van der Sluis, Wouter B; Mermans, Joline F; Buncamper, Marlon E

    2017-07-01

    A 24-year-old transgender woman consulted our outpatient clinic with a painful, itchy and red left labia. She underwent a penile inversion vaginoplasty 18 months before presentation. At physical examination of the left labia, erythema, edema and herpetic vesicles with ulceration were observed. A vesicle fluid swab was obtained and the presence of herpes simplex virus type 1 (HSV-1) was detected by PCR assay. Treatment consisted of oral valaciclovir (500 mg twice daily) for a total of five days.Topically-applied lidocaine cream (3%) was used for pain management. Treatment gave symptom relief in five days. At physical examination 14 days after symptom onset, there were no signs of active infection. To our knowledge, this is the first case report of HSV-1 infection of the neolabia in a transgender woman.

  6. Ataxia espinocerebelar tipo 6: relato de caso

    Directory of Open Access Journals (Sweden)

    Bianca Simone Zeigelboim

    2014-10-01

    Full Text Available O objetivo deste estudo foi verificar as alterações vestibulococleares observadas em um caso de ataxia espinocerebelar tipo 6. O caso foi encaminhado do Hospital de Clínicas para o Laboratório de Otoneurologia de uma Instituição de Ensino e foi submetido aos seguintes procedimentos: anamnese, inspeção otológica, avaliações audiológica e vestibular. O caso retrata uma paciente com diagnóstico genético de ataxia espinocerebelar tipo 6, do sexo feminino, com 57 anos de idade, que referiu desequilíbrio à marcha com tendência a queda para a esquerda, disartria e disfonia. Na avaliação audiológica apresentou configuração audiométrica descendente a partir da frequência de 4kHz e curva timpanométrica do tipo "A" com presença dos reflexos estapedianos bilateralmente. No exame vestibular observou-se na pesquisa da vertigem posicional presença de nistagmo vertical inferior e oblíquo, espontâneo e semiespontâneo múltiplo com características centrais (ausência de latência, paroxismo, fatigabilidade e vertigem, nistagmooptocinético abolido e hiporreflexia à prova calórica. Constataram-se alterações labirínticas que indicaram afecção do sistema vestibular central evidenciando-se a importância dessa avaliação. A existência da possível relação entre os achados com os sintomas vestibulares apresentados pela paciente apontou a relevância do exame labiríntico neste tipo de ataxia uma vez que a presença do nistagmo vertical inferior demonstrou ser frequente neste tipo de patologia.

  7. Obstetric outcomes of human Herpes virus‑2 infection among ...

    African Journals Online (AJOL)

    Objective: This study investigated the obstetric outcomes of herpes simplex virus (HSV‑2) infection among pregnant women. Materials and Methods: In this prospective cohort study, a total of 674 consenting pregnant women attending ante‑natal clinic in the University of Benin Teaching Hospital and Central Hospital Benin ...

  8. Herpes simplex encephalitis | Ladapo | Nigerian Journal of Clinical ...

    African Journals Online (AJOL)

    Nigerian Journal of Clinical Practice. Journal Home · ABOUT · Advanced Search · Current Issue · Archives · Journal Home > Vol 14, No 1 (2011) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register. Herpes simplex encephalitis. TA Ladapo, E Oyenusi, FEA Lesi ...

  9. Serological profiles of Herpes simplex virus type 2 among HIV ...

    African Journals Online (AJOL)

    Herpes simplex virus type-2 (HSV-2) is the major cause of genital ulcer diseases (GUD) consequently a significant factor for the acquisition and transmission of human immunodeficiency virus (HIV). Despite its importance there is paucity of data regarding the magnitude of HSV-2 in non-HIV infected population in ...

  10. Determination of human herpes simplex virus in clear cerebrospinal ...

    African Journals Online (AJOL)

    MICROBIO TA

    The purpose of this study was to test CSF obtained from different regions of Rwanda for herpes simplex viruses (HSV) type 1 and 2 using a commercial multiplex PCR kit. CSF samples were obtained from patients with clinical suspicion of meningitis and encephalitis which may be caused by different microorganisms ...

  11. African traditional medication and keloid formation in herpes zoster ...

    African Journals Online (AJOL)

    Nigerian Journal of Clinical Practice • Oct-Dec 2011 • Vol 14 • Issue 4. Case Report. African traditional medication and keloid formation in herpes zoster ophthalmicus. OO Komolafe, OT Ogunleye, OO Fasina1, OA Komolafe2. Departments of Ophthalmology, and 2Pharmaceutical Service, Federal Medical Centre, Owo, ...

  12. Herpes Zoster Ophthalmicus in a Healthy Nigerian Child

    African Journals Online (AJOL)

    2017-07-26

    Jul 26, 2017 ... Herpes zoster ophthalmicus (HZO) is rare in children especially those who are immunocompetent. We reported a case of HZO in a healthy 3- year-old girl with no history of exposure or underlying immune-compromising systemic disease. She developed severe ocular complications after treatment.

  13. seroprevalence of human herpes virus 8 (hhv8) infection among ...

    African Journals Online (AJOL)

    Praise

    SEROPREVALENCE OF HUMAN HERPES VIRUS 8 (HHV8) INFECTION. AMONG COMMERCIAL SEX WORKERS IN JOS. Zakari1, H., Nimzing2, L., Agabi1, Y. A., Amagam3, P. and Dashen,1 M. M.. 1Department of Microbiology, Faculty of Natural Sciences, University o f Jos, Nigeria. 2Department of Medical Microbiology, ...

  14. Herpes Simplex Virus Infections of the Central Nervous System.

    Science.gov (United States)

    Whitley, Richard J

    2015-12-01

    This article summarizes knowledge of herpes simplex virus (HSV) infections of the central nervous system (CNS). Disease pathogenesis, detection of DNA polymerase chain reaction (PCR) for diagnosis and prognosis, and approaches to therapy warrant consideration. HSV infection of the CNS is one of few treatable viral diseases. Clinical trials indicate that outcome following neonatal herpes simplex virus type 2 (HSV-2) infections of the CNS is significantly improved when 6 months of suppressive oral acyclovir therapy follows IV antiviral therapy. In contrast, herpes simplex virus type 1 (HSV-1) infections of the brain do not benefit from extended oral antiviral therapy. This implies a difference in disease pathogenesis between HSV-2 and HSV-1 infections of the brain. PCR detection of viral DNA in the CSF is the gold standard for diagnosis. Use of PCR is now being adopted as a basis for determining the duration of therapy in the newborn. HSV infections are among the most common encountered by humans; seropositivity occurs in 50% to 90% of adult populations. Herpes simplex encephalitis, however, is an uncommon result of this infection. Since no new antiviral drugs have been introduced in nearly 3 decades, much effort has focused on learning how to better use acyclovir and how to use existing databases to establish earlier diagnosis.

  15. The Use of Iontophoretically Applied Acyclovir on Recurrent Herpes Labialis

    Science.gov (United States)

    1988-08-01

    virus (Notkins et al. 1985). Levamisol , a drug which is thought to increase cell mediated immunity, has also been tried with limited success (Russell...controlled trial of levamisole in the treat- ment of recurrent herpes labialis. J. Infect. Dis. 137:597-599. Schmitt, J.C. 1986. The use of topical alpha

  16. Cost-effectiveness of vaccination against herpes zoster

    NARCIS (Netherlands)

    de Boer, Pieter; Wilschut, Jan C.; Postma, Maarten J.

    Herpes zoster (HZ) is a common disease among elderly, which may develop into a severe pain syndrome labeled postherpetic neuralgia (PHN). A live-attenuated varicella zoster virus vaccine has been shown to be effective in reducing the incidence and burden of illness of HZ and PHN, providing the

  17. Herpes Zoster Ophthalmicus in a Healthy Nigerian Child

    African Journals Online (AJOL)

    Herpes zoster ophthalmicus (HZO) is rare in children especially those who are immunocompetent. We reported a case of HZO in a healthy 3- year-old girl with no history of exposure or underlying immune-compromising systemic disease. She developed severe ocular complications after treatment. Both parents were ...

  18. Computed tomography in young children with herpes simplex virus encephalitis

    Energy Technology Data Exchange (ETDEWEB)

    Sugimoto, T.; Woo, M.; Okazaki, H.; Nishida, N.; Hara, T.; Yasuhara, A.; Kasahara, M.; Kobayashi, Y.

    1985-09-01

    Computed tomographic (CT) scans were obtained from eight infants and young children with herpes simplex virus encephalitis. In two cases the initial scan showed diffuse edematous changes as a mass effect without laterality. Unilateral localized low attenuation in the initial scan was evident 4 days after the onset in one patient, and high attenuation in the initial scan appeared on the 6th day in another patient, but in general, it was not possible to establish an early diagnosis of herpes simplex virus encephalitis from CT scan. In the longitudinal study the calcification with ventriculomegaly appeared in 3 of 5 survivors, and gyriform calcification in 2 of 3 patients, respectively. The appearance of multicystic encephalomalacia was evident in one patient 6 months after the onset of neonatal herpes simplex encephalitis. It is shown that the CT findings of neonates and young children with herpes simplex encephalitis are different from those of older children and adults, and the importance of longitudinal CT studies was stressed in clarifying the pathophysiology of the central nervous system involvement in survivors.

  19. Computed tomography in young children with herpes simplex virus encephalitis.

    Science.gov (United States)

    Sugimoto, T; Woo, M; Okazaki, H; Nishida, N; Hara, T; Yasuhara, A; Kasahara, M; Kobayashi, Y

    1985-01-01

    Computed tomographic (CT) scans were obtained from eight infants and young children with herpes simplex virus encephalitis. In two cases the initial scan showed diffuse edematous changes as a mass effect without laterality. Unilateral localized low attenuation in the initial scan was evident 4 days after the onset in one patient, and high attenuation in the initial scan appeared on the 6th day in another patient, but in general, it was not possible to establish an early diagnosis of herpes simplex virus encephalitis from CT scan. In the longitudinal study the calcification with ventriculomegaly appeared in 3 of 5 survivors, and gyriform calcification in 2 of 3 patients, respectively. The appearance of multicystic encephalomalacia was evident in one patient 6 months after the onset of neonatal herpes simplex encephalitis. It is shown that the CT findings of neonates and young children with herpes simplex encephalitis are different from those of older children and adults, and the importance of longitudinal CT studies was stressed in clarifying the pathophysiology of the central nervous system involvement in survivors.

  20. Herpes zoster myelitis: report of two cases | Amanyo | East African ...

    African Journals Online (AJOL)

    Two male patients aged 40 and 45 years with HIV infection and paraplegia are presented. The two had sub-acute onset paraplegia with a sensory level, which developed 10 days after herpes zoster dermatomal rash. They both had asymmetrically involvement of the lower limbs. Investigation including imaging of the spinal ...

  1. Herpes zoster ophthalmicus in a healthy Nigerian child | Oladigbolu ...

    African Journals Online (AJOL)

    Herpes zoster ophthalmicus (HZO) is rare in children especially those who are immunocompetent. We reported a case of HZO in a healthy 3- year-old girl with no history of exposure or underlying immune-compromising systemic disease. She developed severe ocular complications after treatment. Both parents were non ...

  2. Herpes Simplex Virus Type-2 and Human Immunodeficiency Virus ...

    African Journals Online (AJOL)

    Objectives: To estimate the seroprevalence of Herpes Simplex Type 2 (HSV-2) and its association with Human Immunodeficiency Virus type 1 (HIV-1) infections in rural Kilimanjaro Tanzania. Methods: A cross-sectional survey was conducted in Oria village from March to June 2005 involving all individuals aged 15-44 years ...

  3. Keratitis in association with herpes zoster and varicella vaccines.

    Science.gov (United States)

    Grillo, A P; Fraunfelder, F W

    2017-07-01

    The objective of this review was to collect reports of keratitis in association with herpes zoster virus (HZV) or varicella zoster virus (VZV) vaccines. HZV vaccination is intended for at-risk adult populations and VZV vaccination is intended for all pediatric patients. We reviewed the literature and reports of keratitis in association with herpes zoster or varicella vaccine from the National Registry of Drug-Induced Ocular Side Effects and the World Health Organization. Twenty-four cases of unilateral keratitis in association with VZV vaccines were collected from the adverse reaction databases and literature. In most cases, the onset of keratitis occurred within days of vaccination and resolved with topical steroid eye drops and oral acyclovir. Data suggest that keratitis in association with herpes zoster or varicella vaccine is rare, is usually self-limited or resolves with treatment. The mechanism may be the persistence of viral antigens in the cornea after VZV vaccination or herpes zoster ophthalmicus. This reaction is probable, given the plausible biological mechanism, the temporal relationship between vaccination and keratitis, and overall patterns of presentation after vaccination. Copyright 2017 Clarivate Analytics.

  4. Human Herpes Simplex Virus Type 1 in Confiscated Gorilla

    Science.gov (United States)

    Oxford, Kristie L.; Gardner-Roberts, David; Kinani, Jean-Felix; Spelman, Lucy; Barry, Peter A.; Cranfield, Michael R.; Lowenstine, Linda J.

    2014-01-01

    In 2007, we detected human herpes simplex virus type 1, which caused stomatitis, in a juvenile confiscated eastern lowland gorilla (Gorilla beringei graueri) that had a high degree of direct contact with human caretakers. Our findings confirm that pathogens can transfer between nonhuman primate hosts and humans. PMID:25341185

  5. The "Other" Venereal Diseases: Herpes Simplex, Trichomoniasis and Candidiasis.

    Science.gov (United States)

    McNab, Warren L.

    1979-01-01

    Although the term venereal disease has been synonymous with gonorrhea and syphilis, the Center for Disease Control now states that the number of new cases of herpes simplex, trichomoniasis, and candidiasis is rapidly approaching the number of cases of syphilis and gonorrhea. (MM)

  6. CASE REPORT - Maxillary Herpes Zoster with Corneal Involvement ...

    African Journals Online (AJOL)

    Corneal involvement in maxillary herpes zoster is very rare. This report presents the case of a 32 years old 7 months pregnant para2+1 female, who presented with vesiculopapular rashes with hyperpigmented crusts over the maxillary area of the face on the left side with periocular oedema, conjunctivitis and mild punctate ...

  7. Recurrent herpes simplex virus keratitis in a young Nigerian male ...

    African Journals Online (AJOL)

    Herpes Simplex Virus Keratitis is the infection of cornea by double stranded DNA Viruses.This condition has a tendency to reoccur after a certain period of time. A 25 year old male presented to the clinic with reduced visual acuity, itching, redness, pain and photophobia in the left eye. Onset of symptoms was 10 days prior to ...

  8. Herpes zoster in psoriasis patients treated with tofacitinib

    DEFF Research Database (Denmark)

    Winthrop, Kevin L; Lebwohl, Mark; Cohen, Arnon D

    2017-01-01

    BACKGROUND: Tofacitinib is an oral Janus kinase (JAK) inhibitor. Immunomodulatory therapies can increase the risk for herpes zoster (HZ) in patients with psoriasis. OBJECTIVE: To evaluate the relationship between tofacitinib use and HZ risk. METHODS: We used phases 2 and 3 and long-term extension...

  9. Divergência genética entre genótipos de frangos tipo caipira

    Directory of Open Access Journals (Sweden)

    R. C. Veloso

    2015-10-01

    Full Text Available RESUMOObjetivou-se com este trabalho verificar a divergência genética entre sete genótipos de frangos tipo caipira da linhagem Redbro utilizando as características de desempenho por meio de técnicas de análise multivariada. Foram utilizados 840 pintos de um dia, machos, distribuídos em delineamento inteiramente ao acaso, dos seguintes genótipos: Caboclo, Carijó, Colorpak, Gigante Negro, Pesadão Vermelho, Pescoço Pelado e Tricolor. Após a consistência dos dados, foram avaliadas as seguintes variáveis: ganho em peso médio diário, consumo de ração médio diário e conversão alimentar, para os períodos: 1 a 28, 1 a 56, 1 a 70 e 1 a 84 dias de idade; peso corporal ao nascimento, aos 28, 56, 70 e aos 84 dias de idade. O desempenho dos genótipos foi avaliado por meio da análise de variância multivariada e da função discriminante linear de Fisher, usando os testes do maior autovalor de Roy e da união-interseção de Roy para as comparações múltiplas. O estudo da divergência genética foi feito por meio da análise por variáveis canônicas e pelo método de otimização de Tocher. Os genótipos Caboclo e Gigante Negro apresentaram médias canônicas diferentes dos demais genótipos. As duas primeiras variáveis canônicas explicaram 97,41% da variação entre os genótipos. A divergência genética entre os genótipos avaliados permitiu a formação de quatro grupos com os seguintes genótipos: grupo 1 - Colorpak; grupo 2 - Pesadão Vermelho e Pescoço Pelado; grupo 3 - Carijó e Tricolor; e grupo 4 - Caboclo e Gigante Negro.

  10. Management of herpes labialis triggered by emotional stress

    Directory of Open Access Journals (Sweden)

    Herlambang Prehananto

    2016-12-01

    Full Text Available Background: Herpes labialis is a form of secondary or recurrence of primary herpes simplex infection. Herpes simplex virus is latent. It can reactivate due to reactivation of the virus induced by emotional stress, high fever, ultraviolet exposed, oral mucosal or nerve tissue trauma, immunosuppression condition, and hormonal disorders. Purpose: The study aimed to report the management of patients with herpes labialis on the lower lip triggered by emotional stress. Case: A 58 year-old woman complained of pain in her lower lip. The patient had suffered from the pain since one month ago. The patient had been treated with a lip ointment, triamcinolone acetonid 0.1% (Kenalog®, for 2 weeks, but became thick, dry, and worse. She said that she got many calamities related to her family, leading to the increased busyness and psychologically distressed conditions. Extra oral examination of the lower lip showed erythematous erosion sized 4x4 mm, yellowish red crusting sized 3x4 mm, and translucent multiple vesicles sized 1x1 mm with well circumscribed as well as irregular edges. On palpation submandibular lymph nodes, dextra and sinistra were palpable, rubbery, mobile and painless. Based on intra-oral examination, however, there were no abnormalities. Case management: The diagnosis was determined based on anamnesis, clinical examinations, and supporting examination of Ig M and anti HSV-1 Ig G. The patient then was prescribed systemic and topical Acyclovir. Conclusion: Some laboratory tests are necessary to confirm the diagnosis and determine the accurate therapy of herpes labialis in addition to the history and clinical features.

  11. The dynamics of neopterin level in patients with herpes zoster

    Directory of Open Access Journals (Sweden)

    A. L. Yakubenko

    2015-01-01

    Full Text Available Neopterin is a specific marker of cellular immunity and monocytes/macrophages activation. Correlation between serum neopterin levels and clinical features of herpes zoster is unknown.The objective of the study was to determine the concentration of serum neopterin in patients with herpes zoster.Methods: 55 patients with herpes zoster (30 HIV-positive and 25 HIV-negative were included. Serum neopterin levels were measured three times during the observation period (before onset of treatment with acyclovir, on the 3rd day of treatment and after healing of skin lesions. The clinical course and dynamics of laboratory data were also evaluated.Results: The study showed that elevated serum neopterin levels were found in all patients with herpes zoster. Neopterin concentrations were significantly reduced during acyclovir treatment (from 30 (17; 32 to 12 (11; 27 nmol/L (p = 0,0000001, but remained above the upper limit of normal by the time skin lesions were healed in most patients. Neopterin levels before and after treatment weren’t associated with HIV-status. Neopterin concentration was slightly higher in patients with HIV infection on the third day of observation only, that could reflect the abnormal immunoreactivity of this host. Neopterin levels in patients with varicella zoster viremia were higher compared to patients without viremia on the third day of treatment with acyclovir (23.5 (12,7; 30,0 and 12 (4,2, 24,5 nmol/L, respectively, p = 0,037.Conclusions: These results suggest that the dynamics of serum neopterin could be a marker of effectiveness of immune response in herpes zoster.

  12. Mucopolissacaridose tipo VI: relato de caso

    OpenAIRE

    Lais Orosco Bialon Santana; Carolina Ando Matsuno; Marta Wey Vieira

    2014-01-01

    Introdução: As mucopolissacaridoses são erros inatos do metabolismo de depósito lisossomal subclassificadas segundo a enzima deficiente. A arilsulfatase B (ARSB), responsável por degradar os glicosaminoglicanos (GAGs), que atuam no tecido conjuntivo, é deficiente na mucopolissacaridose tipo VI (MP VI). A MP VI tem clínica variável, sem anormalidades ao nascimento, evidenciando-se progressivamente ao acúmulo de GAGs. O diagnóstico se faz pela redução da atividade da ARSB ou da mutação genética...

  13. O oraloma da diabetes melitos tipo 1 vs diabetes melitos tipo 2 - um estudo comparativo

    OpenAIRE

    Brás, Vítor Daniel Moreira

    2013-01-01

    A Diabetes Melitos é uma doença de grande prevalência a nível mundial e os seus mecanismos fisiopatológicos não são ainda totalmente conhecidos. Actualmente, a terapêutica seguida em casos de Diabetes Melitos é eminentemente sintomática consistindo na administração de insulina nos casos de Diabetes Melitos tipo 1 ou quando se verifica a falência das células beta do pâncreas de pacientes com Diabetes Melitos tipo 2, ou no controlo da glicemia nos casos de Diabetes Melitos ...

  14. The Diagnosis of Genital Herpes – Beyond Culture: An Evidence-Based Guide for the Utilization of Polymerase Chain Reaction and Herpes Simplex Virus Type-Specific Serology

    Directory of Open Access Journals (Sweden)

    S Ratnam

    2007-01-01

    Full Text Available Accurate identification of persons with genital herpes is necessary for optimal patient management and prevention of transmission. Because of inherent inaccuracies, clinical diagnosis of genital herpes should be confirmed by laboratory testing for the causative agents herpes simplex virus type 1 (HSV-1 and HSV type 2 (HSV-2. Further identification of the HSV type is valuable for counselling on the natural history of infection and risk of transmission. Laboratory methods include antigen detection, culture, polymerase chain reaction (PCR and conventional and type-specific serology (TSS. PCR has, by far, the greater sensitivity and should be the test of choice for symptomatic cases. HSV-2 TSS is indicated for patients with genital lesions in whom antigen detection, culture or PCR fail to detect HSV, and for patients who are asymptomatic but have a history suggestive of genital herpes. HSV-2 TSS is further indicated for patients infected with HIV. HSV-2 TSS along with HSV-1 TSS may be considered, as appropriate, in evaluating infection and/or immune status in couples discordant for genital herpes, women who develop their first clinical episode of genital herpes during pregnancy, asymptomatic pregnant women whose partners have a history of genital herpes or HIV infection, and women contemplating pregnancy or considering sexual partnership with those with a history of genital herpes. The above should be performed in conjunction with counselling of infected persons and their sex partners.

  15. Avaliação radiográfica da localização de caninos superiores não irrompidos Radiographic evaluation of localization for non-erupted upper canines

    Directory of Open Access Journals (Sweden)

    Patrícia Paschoal Martins

    2005-08-01

    Full Text Available A erupção ectópica e a impacção de caninos superiores são problemas bastante comuns na população. A excelência do tratamento ortod��ntico traduz-se na correção da oclusão, harmonia do sorriso, saúde periodontal e estabilidade pós-tratamento. Para obtermos tais condições, a manutenção dos caninos é fundamental. Portanto, o objetivo deste estudo foi avaliar radiograficamente a localização de caninos superiores não irrompidos utilizando-se radiografias panorâmicas. Foram selecionadas setenta radiografias panorâmicas de pacientes com impacção uni ou bilateral de caninos, candidatos a tratamento cirúrgico. Para determinação da posição espacial dos caninos superiores não irrompidos foram selecionados métodos descritos na literatura e uma avaliação proposta neste trabalho. A localização de caninos não irrompidos é fundamental para estabelecer o plano de tratamento, auxiliando no acesso cirúrgico e na direção das forças ortodônticas a serem aplicadas no dente impactado. Os pacientes que tiveram suas radiografias utilizadas neste estudo serão tratados pelas disciplinas de Ortodontia e Cirurgia, com exodontia do canino ou exposição cirúrgica para colagem do dispositivo de tracionamento associada ao tratamento ortodôntico corretivo.Ectopic eruption and the impaction of upper canines are problems quite commonly presented by the population. An excellent orthodontic treatment encompasses occlusal correction, smile harmony, periodontal health and posttreatment stability. Such conditions can be obtained upon the due maintenance of the canines, therefore, the aim of this study is to assess the radiographic localization of non-erupted upper canines using panoramic radiographs. In this study, seventy panoramic radiographs of patients presented with uni or bilateral canine impaction, applying for surgical treatment, were selected. Methods described in the literature and an evaluation proposed in this work were

  16. Glaucoma secundario a neurofibromatosis tipo-1

    Directory of Open Access Journals (Sweden)

    Anay Martínez Díaz

    2012-02-01

    Full Text Available Paciente de 59 años de edad, con antecedentes de neurofibromatosis tipo 1 y trauma contuso del ojo derecho desde hace años. Acudió a consulta de oftalmología refiriendo disminución lenta de la visión; al examen físico se constató una agudeza visual de 0.6 en ambos ojos, así como disminución concéntrica del campo visual en la perimetría por confrontación. El examen objetivo mostró en los anexos una pingüécula en ojo derecho y pterigion grado II en ojo izquierdo; en segmento anterior, múltiples nódulos de Lisch en el iris de ambos ojos, y en el ojo derecho, pupila ligeramente midriática, pero reactiva. Se le realizó gonoscopia, oftalmoscopia y perimetría Humphry; en esta última se halló un escotoma arqueado en ojo derecho, y un defecto superior arqueado en el ojo izquierdo. Se concluyó el caso con los diagnósticos de catarata presenil incipiente y glaucoma secundario a neurofibromatosis tipo 1.

  17. Herp regulates Hrd1-mediated ubiquitylation in a ubiquitin-like domain-dependent manner

    DEFF Research Database (Denmark)

    Kny, Melanie; Standera, Sybille; Hartmann-Petersen, Rasmus

    2011-01-01

    Accumulation of aberrant proteins in the endoplasmic reticulum (ER) triggers the unfolded protein response pathway that helps the cell to survive under these stress conditions. Herp is a mammalian ubiquitin domain protein, which is strongly induced by the unfolded protein response. It is involved...... found that upon exposure of cells to ER stress, elevation of Herp steady state levels is accompanied by an enhanced association of Herp with pre-existing Hrd1. Hrd1-associated Herp is rapidly degraded and substituted by de novo synthesized Herp, suggesting a continuous turnover of the protein at Hrd1...... necessary for NHK degradation. In summary, we propose that binding of Herp to Hrd1-containing ERAD complexes positively regulates the ubiquitylation activity of these complexes, thus permitting survival of the cell during ER stress....

  18. Guidance on Management of Asymptomatic Neonates Born to Women With Active Genital Herpes Lesions

    OpenAIRE

    Kimberlin, David W.; Baley, Jill; Brady, Michael T.; Byington, Carrie L.; Davies, H Dele; Edwards, Kathryn M.; Glode, Mary P.; Jackson, Mary Anne; Keyserling, Harry L.; Maldonado, Yvonne A.; Murray, Dennis L.; Orenstein, Walter A.; Schutze, Gordon E.; Willoughby, Rodney E.; Zaoutis, Theoklis E

    2013-01-01

    Herpes simplex virus (HSV) infection of the neonate is uncommon, but genital herpes infections in adults are very common. Thus, although treating an infant with neonatal herpes is a relatively rare occurrence, managing infants potentially exposed to HSV at the time of delivery occurs more frequently. The risk of transmitting HSV to an infant during delivery is determined in part by the mother’s previous immunity to HSV. Women with primary genital HSV infections who are shedding HSV at deliver...

  19. Oral erythema multiforme: Laboratory findings in monitoring Herpes simplex virus involvement (A case report)

    OpenAIRE

    Maria Leny Raiyon; Gus Permana Subita

    2008-01-01

    Erythema Multiforme is polymorphous recurrent eruptions on the skin and oral mucosa. This case is describing a progression of a case of Erythema Multiforme in the oral mucosa of a 33-year-old man suggesting of herpes viral involvement. In the absence of identified inducing drugs, past medical history of clinical manifestation on Herpes Simplex Viral (HSV) but positive serum antibody against HSV-1 is suggesting of Herpes Associated Erythema Multiforme. This became the basis of the patient mana...

  20. Association of human endogenous retroviruses with multiple sclerosis and possible interactions with herpes viruses

    DEFF Research Database (Denmark)

    Christensen, Tove

    2005-01-01

    may be members of the Herpesviridae. Several herpes viruses, such as HSV-1, VZV, EBV and HHV-6, have been associated with MS pathogenesis, and retroviruses and herpes viruses have complex interactions. The current understanding of HERVs, and specifically the investigations of HERV activation...... and expression in MS are the major subjects of this review, which also proposes to synergise the herpes and HERV findings, and presents several possible pathogenic mechanisms for HERVs in MS. Copyright (c) 2005 ...

  1. The role of oral acyclovir in the management of genital herpes simplex.

    OpenAIRE

    Sacks, S L

    1987-01-01

    Oral acyclovir is an antiviral nucleoside analogue that has recently been released in Canada for use in selected patients with genital infections by the herpes simplex virus. First episodes of genital herpes should be treated with oral acyclovir as soon as the diagnosis is considered. Most people with recurrent genital herpes do not require systemic drug therapy. Selected patients with severe or long-lasting recurrences, recurrences associated with long prodromal periods (greater than 12 to 2...

  2. Apparent rarity of asymptomatic herpes cervicitis in a woman with intra-uterine contraceptive device

    Directory of Open Access Journals (Sweden)

    Adeola Fowotade

    2013-12-01

    Full Text Available Infection with genital herpes simplex virus (HSV remains a common viral sexually transmitted disease, often subclinical and a major worldwide problem of women of reproductive age group. Herpes cervicitis is an unusual presentation of Herpes simplex virus infection in females. The finding of herpes cervicitis on routine pap smear of an asymptomatic woman on Intrauterine contraceptive device still further supports the need for increased awareness on the possibility of Herpes simplex virus infection among women, particularly those on Intrauterine contraceptive device. The index case is a 28 years old Nigerian female who was referred to our Special Treatment Clinic on account of an abnormal pap smear cytology which was in keeping with Herpes cervicitis. There was no history of genital ulcer in this patient; however ELISA for HSV 2 IgM was positive in her. We therefore describe a case of herpes cervicitis in an asymptomatic woman on intrauterine contraceptive device. This case highlights to clinicians the need to be aware of the possibility of this association and to carry out relevant investigations so as to identify and treat these patients appropriately. Therefore, there is a need to put in place adequate public health intervention strategy to prevent genital herpes in women of reproductive age group with a view to preventing the possibility of congenital herpes in subsequent pregnancy.

  3. Herpes Zoster Duplex Bilateralis in Immuno-Competent Patients: Report of Two Cases

    Science.gov (United States)

    Dalela, Gaurav

    2015-01-01

    Herpes Zoster is a common viral disorder, occurs due to reactivation of latent Varicella Zoster Virus (VZV) usually in adults or elderly patients, usually confined to a single dermatome. Herpes zoster duplex is a rare but well established entity which is simultaneous, occurring of herpes zoster at two different non contiguous dermatomes, can be unilateralis or bilateralis. Here we are reporting two cases of herpes zoster duplex bilateralis, in case-1 lesions occurs in two different distant dermatomes while in case-2 it appeared in a single dermatome but both sides were involved. Both the patients were healthy immuno-competent male. PMID:26816979

  4. Apparent Rarity of Asymptomatic Herpes Cervicitis in a Woman with Intra-Uterine Contraceptive Device.

    Science.gov (United States)

    Fowotade, Adeola; Okolo, Abu Clement; Manga, Mohammed Mohammed; Anaedobe, Chinenye Gloria; Salami, Ayodeji Akeem; Akang, Effiong Essien Udo

    2013-12-03

    Infection with genital herpes simplex virus (HSV) remains a common viral sexually transmitted disease, often subclinical and a major worldwide problem of women of reproductive age group. Herpes cervicitis is an unusual presentation of Herpes simplex virus infection in females. The finding of herpes cervicitis on routine pap smear of an asymptomatic woman on Intrauterine contraceptive device still further supports the need for increased awareness on the possibility of Herpes simplex virus infection among women, particularly those on Intrauterine contraceptive device. The index case is a 28 years old Nigerian female who was referred to our Special Treatment Clinic on account of an abnormal pap smear cytology which was in keeping with Herpes cervicitis. There was no history of genital ulcer in this patient; however ELISA for HSV 2 IgM was positive in her. We therefore describe a case of herpes cervicitis in an asymptomatic woman on intrauterine contraceptive device. This case highlights to clinicians the need to be aware of the possibility of this association and to carry out relevant investigations so as to identify and treat these patients appropriately. Therefore, there is a need to put in place adequate public health intervention strategy to prevent genital herpes in women of reproductive age group with a view to preventing the possibility of congenital herpes in subsequent pregnancy.

  5. Unusual Clinical Presentation and Role of Decompressive Craniectomy in Herpes Simplex Encephalitis.

    Science.gov (United States)

    Singhi, Pratibha; Saini, Arushi Gahlot; Sahu, Jitendra Kumar; Kumar, Nuthan; Vyas, Sameer; Vasishta, Rakesh Kumar; Aggarwal, Ashish

    2015-08-01

    Decompressive craniectomy in pediatric central nervous infections with refractory intracranial hypertension is less commonly practiced. We describe improved outcome of decompressive craniectomy in a 7-year-old boy with severe herpes simplex encephalitis and medically refractory intracranial hypertension, along with a brief review of the literature. Timely recognition of refractory intracranial hypertension and surgical decompression in children with herpes simplex encephalitis can be life-saving. Additionally, strokelike atypical presentations are being increasingly recognized in children with herpes simplex encephalitis and should not take one away from the underlying herpes simplex encephalitis. © The Author(s) 2014.

  6. Granulomatous herpes simplex encephalitis in an infant with multicystic encephalopathy: a distinct clinicopathologic entity?

    Science.gov (United States)

    Schutz, Peter W; Fauth, Clarissa T; Al-Rawahi, Ghada N; Pugash, Denise; White, Valerie A; Stockler, Sylvia; Dunham, Christopher P

    2014-04-01

    Herpes simplex virus encephalitis can manifest as a range of clinical presentations including classic adult, neonatal, and biphasic chronic-granulomatous herpes encephalitis. We report an infant with granulomatous herpes simplex virus type 2 encephalitis with a subacute course and multicystic encephalopathy. A 2-month-old girl presented with lethargy and hypothermia. Computed tomography scan of the head showed multicystic encephalopathy and calcifications. Cerebrospinal fluid analysis by polymerase chain reaction testing for herpes simplex virus 1 and 2, enterovirus, and cytomegalovirus was negative. Normal cerebrospinal fluid interferon-α levels argued against Aicardi-Goutières syndrome. The patient died 2 weeks after presentation. At autopsy, multicystic encephalopathy was confirmed with bilateral gliosis, granulomatous inflammation with multinucleated giant cells, and calcifications. Bilateral healing necrotizing retinitis suggested a viral etiology, but retina and brain were free of viral inclusions and immunohistochemically negative for herpes simplex virus-2 and cytomegalovirus. However, polymerase chain reaction analysis showed herpes simplex virus-2 DNA in four cerebral paraffin blocks. Subsequent repeat testing of the initial cerebrospinal fluid sample using a different polymerase chain reaction assay was weakly positive for herpes simplex virus-2 DNA. Granulomatous herpes simplex virus encephalitis in infants can present with subacute course and result in multicystic encephalopathy with mineralization and minimal cerebrospinal fluid herpes simplex virus DNA load. Infectious etiologies should be carefully investigated in the differential diagnosis of multicystic encephalopathy with mineralization, in particular if multinucleated giant cells are present. Copyright © 2014 Elsevier Inc. All rights reserved.

  7. Rare Occurrence of Herpes Zoster of Trigeminal Nerve following Extraction of Tooth

    Directory of Open Access Journals (Sweden)

    A. Winnifred Christy

    2015-01-01

    Full Text Available Herpes Zoster also known as Shingles is an acute viral infection which is an extremely painful and incapacitating ailment. It results from the reactivation of the varicella zoster virus. The triggering factors for the onset of an attack of Herpes Zoster include some form of immunosuppression. The diagnosis of Herpes Zoster can be made on proper medical history and a thorough clinical examination. Here is the report of a male patient affected by Herpes Zoster infection which followed after extraction of a lower first molar.

  8. Herpes zoster in multiple myeloma patients during bortezomib treatment

    Directory of Open Access Journals (Sweden)

    I. N. Nazarova

    2011-01-01

    Full Text Available Recent advances in multiple myeloma (MM treatment associated with new drug use including bortezomib. Experiences in wide ambul atory drug use confirm therapy success for this serious disease, but at the same time reveals the most common side effects. One of th e most significant is the reactivation of Herpes zoster , which leads to decrease MM therapy results because of inability to perform standard therapy in these patients. Literature data and own experiences about reactivation of Herpes zoster during bortezomib therapy as monothe rapy and in combination, which varies from 7 to 34% according to different authors and 25% of own experiences, is presented. Treatment and preventive schedule of this complication are shown.

  9. Herpes Simplex Virus-2 Esophagitis in a Young Immunocompetent Adult.

    Science.gov (United States)

    Kadayakkara, Deepak K; Candelaria, Angela; Kwak, Ye Eun; Loeser, Caroline

    2016-01-01

    Herpes simplex esophagitis (HSE) is commonly identified in immunosuppressed patients. It is rare among immunocompetent patients and almost all of the reported cases are due to HSV-1 infection. HSV-2 esophagitis is extremely rare. We report the case of a young immunocompetent male who presented with dysphagia, odynophagia, and epigastric pain. Endoscopy showed multitudes of white nummular lesions in the distal esophagus initially suspected to be candida esophagitis. However, classic histopathological findings of multinucleated giant cells with eosinophilic intranuclear inclusions and positive HSV-2 IgM confirmed the diagnosis of HSV-2 esophagitis. The patient rapidly responded to acyclovir treatment. Although HSV-2 is predominantly associated with genital herpes, it can cause infections in other parts of the body previously attributed to only HSV-1 infection.

  10. Penile herpes zoster: an unusual location for a common disease

    Directory of Open Access Journals (Sweden)

    Milan Bjekic

    Full Text Available Herpes zoster is a common dermatological condition which affects up to 20% of the population, most frequently involving the thoracic and facial dermatomes with sacral lesions occurring rarely and only a few reported cases of penile shingles. Case report: We report two cases of unusual penile clinical presentations of varicella zoster virus infection in immunocompetent men. The patients presented with grouped clusters of vesicles and erythema on the left side of penile shaft and posterior aspect of the left thigh and buttock, involving s2-s4 dermatomes. The lesions resolved quickly upon administration of oral antiviral therapy. Conclusion: Penile herpes zoster should not be overlooked in patients with unilateral vesicular rash.

  11. Superior orbital fissure syndrome in herpes zoster ophthalmicus.

    LENUS (Irish Health Repository)

    Kirwan, R P

    2012-02-01

    AIM: To report a case of superior orbital fissure syndrome (SOFS) in a patient with herpes zoster ophthalmicus (HZO). MATERIALS AND METHODS: A case report. RESULTS: A 71-year-old male with HZO presented acutely to accident and emergency complaining of right vision loss, double vision and drowsiness. The right visual acuity was counting fingers. There was no relative afferent pupillary defect. He had interstitial keratitis, ptosis, proptosis and total ophthalmoplaegia. The signs indicated HZO complicated by SOFS. Brain imaging and lumbar puncture confirmed the diagnosis of varicella zoster encephalitis. Systemic acyclovir and prednisolone led to recovery of visual acuity and ocular motility in addition to resolution of his proptosis and ptosis. CONCLUSION: SOFS is a rare complication of herpes zoster infection. With the appropriate treatment and follow-up, patients may be reassured that recovery of their visual acuity and ocular motility will occur.

  12. Vaccines for preventing herpes zoster in older adults

    Directory of Open Access Journals (Sweden)

    Ana M. Z. Gagliardi

    Full Text Available BACKGROUND:Herpes zoster or, as it is commonly called, 'shingles' is a neurocutaneous disease characterised by the reactivation of varicella zoster virus (VZV, the virus that causes chickenpox, which is latent in the dorsal spinal ganglia when immunity to VZV declines. It is an extremely painful condition which can often last for many weeks or months, impairing the patient's quality of life. The natural aging process is associated with a reduction of cellular immunity which predisposes to herpes zoster. Vaccination with an attenuated form of VZV activates specific T cell production, therefore avoiding viral reactivation. A herpes zoster vaccine with an active virus has been approved for clinical use among older adults by the Food and Drug Administration and has been tested in large populations.OBJECTIVE:To evaluate the effectiveness and safety of vaccination for preventing herpes zoster in older adults.METHODSSearch methods: We searched the following sources for relevant studies: CENTRAL 2012, Issue 7, MEDLINE (1948 to July week 1, 2012, EMBASE (2010 to July 2012, LILACS (1982 to July 2012 and CINAHL (1981 to July 2012. We also reviewed reference lists of identified trials and reviews for additional studies.Selection criteria: Randomised controlled trials (RCTs or quasi-RCTs comparing zoster vaccine with placebo or no vaccine, to prevent herpes zoster in older adults (mean age > 60 years.Data collection and analysis: Two review authors independently collected and analysed data using a data extraction form. They also carried out an assessment of risk of bias.MAIN RESULTS:We identified eight RCTs with a total of 52,269 participants. Three studies were classified at low risk of bias. The main outcomes on effectiveness and safety were extracted from one clinical trial with a low risk of bias. Four studies compared zoster vaccine versus placebo; one study compared high-potency zoster vaccine versus low-potency zoster vaccine; one study compared

  13. Neonatal herpes simplex virus infection: epidemiology and treatment.

    Science.gov (United States)

    James, Scott H; Kimberlin, David W

    2015-03-01

    Herpes simplex virus types 1 (HSV-1) and 2 (HSV-2) are highly prevalent viruses capable of establishing lifelong infection. Genital herpes in women of childbearing age represents a major risk for mother-to-child transmission (MTCT) of HSV infection, with primary and first-episode genital HSV infections posing the highest risk. The advent of antiviral therapy with parenteral acyclovir has led to significant improvement in neonatal HSV disease mortality. Further studies are needed to improve the clinician's ability to identify infants at increased risk for HSV infection and prevent MTCT, and to develop novel antiviral agents with increased efficacy in infants with HSV infection. Copyright © 2015 Elsevier Inc. All rights reserved.

  14. Autophagy interaction with herpes simplex virus type-1 infection

    Science.gov (United States)

    O'Connell, Douglas; Liang, Chengyu

    2016-01-01

    abstract More than 50% of the U.S. population is infected with herpes simplex virus type-I (HSV-1) and global infectious estimates are nearly 90%. HSV-1 is normally seen as a harmless virus but debilitating diseases can arise, including encephalitis and ocular diseases. HSV-1 is unique in that it can undermine host defenses and establish lifelong infection in neurons. Viral reactivation from latency may allow HSV-1 to lay siege to the brain (Herpes encephalitis). Recent advances maintain that HSV-1 proteins act to suppress and/or control the lysosome-dependent degradation pathway of macroautophagy (hereafter autophagy) and consequently, in neurons, may be coupled with the advancement of HSV-1-associated pathogenesis. Furthermore, increasing evidence suggests that HSV-1 infection may constitute a gradual risk factor for neurodegenerative disorders. The relationship between HSV-1 infection and autophagy manipulation combined with neuropathogenesis may be intimately intertwined demanding further investigation. PMID:26934628

  15. Associations between individual and relationship characteristics and genital herpes disclosure.

    Science.gov (United States)

    Myers, Jaime L; Buhi, Eric R; Marhefka, Stephanie; Daley, Ellen; Dedrick, Robert

    2016-10-01

    Disclosure is often a challenge for individuals living with genital herpes. This study explores determinants of genital herpes disclosure with one's most recent sexual partner using an online questionnaire (n = 93). The majority of participants reported (80.4%) disclosure. Among non-disclosers, fear of negative partner reactions was the primary reason for non-disclosure. Age, relationship commitment, time in relationship, and expectations of partner's reaction were statistically significant predictors at the bivariate level. Reaction expectations and relationship commitment remained significant in the multivariate logistic regression model. Findings indicate that future disclosure research should focus on relationship context and managing negative expectations to increase disclosure. © The Author(s) 2015.

  16. Evolution of rational vaccine designs for genital herpes immunotherapy.

    Science.gov (United States)

    Kaufmann, Johanna Katharina; Flechtner, Jessica Baker

    2016-04-01

    Immunotherapeutic vaccines have emerged as a novel treatment modality for genital herpes, a sexually transmitted disease mainly caused by herpes simplex virus type 2. The approaches to identify potential vaccine antigens have evolved from classic virus attenuation and characterization of antibody and T cell responses in exposed, but seronegative individuals, to systematic screens for novel T cell antigens. Combined with implementation of novel vaccine concepts revolving around immune evasion and local recruitment of immune effectors, the development of a safe and effective therapeutic vaccine is within reach. Here, we describe the vaccine approaches that currently show promise at clinical and pre-clinical stages and link them to the evolving scientific strategies that led to their identification. Copyright © 2016 Elsevier B.V. All rights reserved.

  17. Acute hemorrhagic leukoencephalitis mimicking herpes simplex encephalitis: case report

    Directory of Open Access Journals (Sweden)

    Martins Henrique Milhomem

    2004-01-01

    Full Text Available Acute hemorrhagic leukoencephalitis (AHLE is a more severe form of acute disseminated encephalomyelities (ADEM characterized by a fulminant clinical course and the presence of hemorrhagic necrosis of the white matter. We report the case of a 57-year-old woman who developed delirium following a respiratory infection. Magnetic resonance imaging of the brain disclosed signal abnormalities in the frontal and temporal lobes, usually found in herpes simplex encephalitis (HSE. Gram stain, India ink and acid-fast bacilli staining were all negative in CSF as was a polymerase chain reaction (PCR for herpes simplex virus. A diagnosis of AHLE was made and the patient was treated with IV methylprednisolone 1g/day for 5 days. Despite treatment, the patient developed several neurological sequelae compatible with the severity of her illness.

  18. Diabetes tipo II e resolvinas D1

    OpenAIRE

    Silva, Isabel Alexandra Marques Batista da

    2015-01-01

    Dissertação para obtenção do grau de Mestre no Instituto Superior de Ciências da Saúde Egas Moniz A diabetes é um problema de saúde pública crescente com o envelhecimento da população, os maus hábitos alimentares e o sedentarismo. A obesidade poderá ser causa ou consequência da diabetes tipo II, sendo também um problema crescente de saúde pública. Esta monografia tem como objetivo estudar, com base no conhecimento atual, se as resolvinas D1 são uma alternativa viável na terapêutica da diab...

  19. Estatuas militares de tipo Sessa Aurunca

    Directory of Open Access Journals (Sweden)

    Ojeda, David

    2014-12-01

    Full Text Available This article re-examines the cuirassed statues of Sessa Aurunca type. I propose including one new sculpture in this group: A ‘Lucius Verus’ colossal cuirassed statue from Seleucia Pieria, which will shed further light on this typology and its use by the Roman emperors.Este artículo retoma el estudio de las estatuas militares de tipo Sessa Aurunca. Propongo la inclusión de una nueva pieza dentro de este grupo: una escultura militar colosal de Lucio Vero procedente de Seleucia Pieria. Su análisis permitirá conocer nuevos detalles acerca de esta tipología estatuaria y su utilización por parte de los emperadores romanos.

  20. ASPECTOS HISTÓRICOS, EPIDEMIOLÓGICOS Y PATOLÓGICOS DE LAS HELICOBACTERIAS EN HUMANOS Y EN CANINOS

    Directory of Open Access Journals (Sweden)

    Diana Naranjo Restrepo

    2012-04-01

    Full Text Available El Helicobacter pylori -bacteria del género Helicobacter- está presente en la mucosa gástrica de los humanos- y se relaciona con la etiología de enfermedades ácido-pépticas benignas y malignas, de las cuales hacen parte las gastritis, úlceras de tipo gástrico y duodenal, adenocarcinoma gástrico y linfoma gástrico no Hodgkin del tejido linfoide asociado a la mucosa (MALT. Esto le ha dado relevancia a su diagnóstico temprano y tratamiento, incentivando el estudio sobre factores de riesgo, medio de contagio y prevalencia con alta implicación en salud pública. A su vez se han realizado investigaciones que han evidenciado la presencia de especies Helicobacter en la mucosa de animales domésticos, de los géneros H. heilmanni, felis y rappini, con posible colonización en mucosa gástrica humana, implicando un componente zoonótico. Existe gran interés por parte del personal de salud en el conocimiento de su prevalencia en la población en general, tipos de transmisión, manifestaciones clínicas, diagnóstico y tratamiento. Debido a la popularidad del tema del H. pylori -tanto en manifestaciones clínicas como en el pronto tratamiento farmacológico- se ha venido encontrando resistencia bacteriana de manera creciente en la población tratada. Esto ha obligado a la comunidad científica a desarrollar vacunas con efecto profiláctico y terapéutico.

  1. Herpes simplex virus bronchiolitis in a cannabis user

    Directory of Open Access Journals (Sweden)

    Daniel H. Libraty

    2014-01-01

    Full Text Available Herpes simplex virus (HSV lower respiratory tract infections in adults are uncommon. We present a case of HSV bronchiolitis and pneumonitis in an immunocompetent individual, likely linked to chronic habitual marijuana use and a herpetic orolabial ulcer. The case serves as a reminder to consider HSV as a potential unusual cause of lower respiratory tract infection/inflammation in individuals with chronic habitual marijuana use.

  2. Fifteen minute consultation: Managing neonatal and childhood herpes encephalitis

    OpenAIRE

    Le Doare, K; Menson, E; Patel, D.; Lim, M; Lyall, H; Herberg, J

    2014-01-01

    Herpes simplex encephalitis (HSE) is the most common single cause of viral encephalitis in infants and children. Treated or untreated, it can be associated with considerable morbidity and mortality, and its presentation is usually insidious and non-specific. Prompt and careful investigation is important in order to establish the diagnosis so that treatment can be optimised. We address some common questions arising when diagnosing and treating presumed HSE throughout childhood.

  3. Psychosocial implications of recurrent genital herpes simplex virus infection.

    OpenAIRE

    Goldmeier, D; Johnson, A.; Byrne, M.; Barton, S

    1988-01-01

    Fifty seven patients experiencing first attacks of genital herpes simplex virus infection (HSVI) were compared with 50 patients who were concerned about frequently recurring attacks despite routine counselling and reassurance. Using the general health questionnaire this latter group was found to be more psychologically distressed and more socially naive than the first attack group, as measured by socioeconomic class and the lie score of the Eysenck personality questionnaire; otherwise the two...

  4. Fifteen minute consultation: Managing neonatal and childhood herpes encephalitis

    Science.gov (United States)

    Le Doare, K; Menson, Esse; Patel, Deepak; Lim, Ming; Lyall, Hermione; Herberg, Jethro

    2015-01-01

    Herpes simplex encephalitis (HSE) is the most common single cause of viral encephalitis in infants and children. Treated or untreated, it can be associated with considerable morbidity and mortality, and its presentation is usually insidious and non-specific. Prompt and careful investigation is important in order to establish the diagnosis so that treatment can be optimised. We address some common questions arising when diagnosing and treating presumed HSE throughout childhood. PMID:25112286

  5. Prevention and management of neonatal herpes simplex virus infections

    OpenAIRE

    Allen, Upton D; Robinson, Joan L

    2014-01-01

    Human herpes simplex virus (HSV) infection in neonates can result in devastating outcomes, including mortality and significant morbidity. All infants are potentially at risk for neonatal HSV infection. This position statement reviews epidemiology, transmission and risk factors, with a focus on intrapartum infection. It considers diagnosis and prognosis according to infection category, along with testing modalities and limitations. Recommendations for managing newborns known to have been expos...

  6. Cytodiagnosis of herpes simplex mastitis: Report of a rare case

    Directory of Open Access Journals (Sweden)

    Mardi Kavita

    2009-01-01

    Full Text Available Herpes simplex virus (HSV is a rare cause of breast infection. Few cases of maternal-infant transmission of the virus during breastfeeding resulting in nipple lesions have been documented. Only three cases have been reported in nonlactating women. We report an additional case of HSV mastitis in a 36-year-old nonlactating female who was diagnosed on scrape cytology smears.

  7. Herpes zoster infection, vaccination and immunocompromised rheumatology patients.

    LENUS (Irish Health Repository)

    O'Connor, Mortimer B

    2013-01-01

    Varicella is a self-limiting and relatively mild disease of childhood, although it is frequently more severe and complicated among the immunocompromised rheumatology patients on immunomodulator therapies. In addition, future reactivation of the dormant virus in dorsal root ganglia may cause herpes zoster infection, which can be very debilitating. In this manuscript, we discuss the nature of this infection along with its potential vaccine especially among rheumatology patients.

  8. Clinical Herpes Zoster in Antarctica as a Model for Spaceflight.

    Science.gov (United States)

    Reyes, David P; Brinley, Alaina A; Blue, Rebecca S; Gruschkus, Stephen K; Allen, Andrew T; Parazynski, Scott E

    2017-08-01

    Antarctica is a useful analog for spaceflight, as both environments are remote, isolated, and with limited resources. While previous studies have demonstrated increased asymptomatic viral shedding in both the Antarctic and spaceflight environments, clinical manifestations of reactivated viral disease have been less frequently identified. We sought to identify the incidence of clinical herpes zoster from viral reactivation in the Antarctic winter-over population. Medical records from the 2014 winter season were reviewed for the incidence of zoster in U.S. Antarctic personnel and then compared to the age-matched U.S. Five cases of clinical herpes zoster occurred in the Antarctic Station population of 204 persons, for an incidence of 33.3 per 1000 person-years vs. 3.2 per 1000 person-years in the general population. Four cases were in persons under age 40, yielding an incidence of 106.7 per 1000 person-years in persons ages 30-39 compared to an incidence of 2.0 per 1000 person-years in the same U.S. age group. Immune suppression due to the stressful Antarctic environment may have contributed to the increased incidence of herpes zoster in U.S. Antarctic personnel during the winter of 2014. Working and living in isolated, confined, and extreme environments can cause immune suppression, reactivating latent viruses and increasing viral shedding and symptomatic disease. Such changes have been observed in other austere environments, including spaceflight, suggesting that clinical manifestations of viral reactivation may be seen in future spaceflight.Reyes DP, Brinley AA, Blue RS, Gruschkus SK, Allen AT, Parazynski SE. Clinical herpes zoster in Antarctica as a model for spaceflight. Aerosp Med Hum Perform. 2017; 88(8):784-788.

  9. Polymerase chain reaction to search for Herpes viruses in uveitic ...

    African Journals Online (AJOL)

    Cite as: Laaks D, Smit DP, Harvey J. Polymerase chain reaction to search for Herpes viruses in uveitic and healthy eyes: a South African perspective. Afri Health Sci. 2015;15(3):748-54. doi: http://dx.doi.org/10.4314/ahs.v15i3.7. Introduction. Uveitis is internationally classified according to the an- atomical locus of infection: ...

  10. Post herpes-zoster scar sarcoidosis with pulmonary involvement

    Directory of Open Access Journals (Sweden)

    Archana Singal

    2014-01-01

    Full Text Available Cutaneous sarcoidosis presents with a wide range of clinical presentations. An uncommon cutaneous manifestation is infiltration of old cutaneous scars with non-caseating granulomas known as scar sarcoidosis. Most of the patients with this clinical entity have other systemic manifestations, particularly pulmonary changes. We report a case of a 50 years old man, presenting with cutaneous sarcoidosis overlying scars of healed herpes zoster.

  11. CURRENT STATE OF HERPES VIRUS TYPE 6 IN CHILDREN

    Directory of Open Access Journals (Sweden)

    M. V. Demidova

    2013-01-01

    Full Text Available The article presents a review of modern literature on infections associated with human herpes virus type 6 (HHV-6. HHV-6 causes exanthem subitum (roseola, and fever without a rash as well as infants’ fever with convulsive disorder and infectious mononucleosis. To diagnose HHV-6 methods of detection of antibodies for the IgM and IgG or PCR are applied in practice.

  12. Generalized acute mucocutaneous herpes simplex type 2 with fatal outcome.

    Science.gov (United States)

    Lopyan, L; Young, A W; Menegus, M

    1977-06-01

    To our knowledge, we present the first culturally documented case of generalized acute mucocutaneous herpes simplex type 2 in an immunosuppressed adult who died during the course of the disease. The picture of the clinical spectrum of herpetic disease in immunosuppressed patients is detailed, and the need for typing the virus, particularly in the disseminated form, and for clarifying possible differences in epidemiology, clinical expression, and prognosis is emphasized.

  13. Eye and Periocular Skin Involvement in Herpes Zoster Infection

    Science.gov (United States)

    Kalogeropoulos, Chris D.; Bassukas, Ioannis D.; Moschos, Marilita M.; Tabbara, Khalid F.

    2015-01-01

    Herpes zoster ophthalmicus (HZO) is a clinical manifestation of the reactivation of latent varicella zoster virus (VZV) infection and is more common in people with diminished cell-mediated immunity. Lesions and pain correspond to the affected dermatomes, mostly in first or second trigeminal branch and progress from maculae, papules to vesicles and form pustules, and crusts. Complications are cutaneous, visceral, neurological, ocular, but the most debilitating is post-herpetic neuralgia. Herpes zoster ophthalmicus may affect all the ophthalmic structures, but most severe eye-threatening complications are panuveitis, acute retinal necrosis (ARN) and progressive outer retinal necrosis (PORN) as well. Antiviral medications remain the primary therapy, mainly useful in preventing ocular involvement when begun within 72 hours after the onset of the rash. Timely diagnosis and management of HZO are critical in limiting visual morbidity. Vaccine in adults over 60 was found to be highly effective to boost waning immunity what reduces both the burden of herpes zoster (HZ) disease and the incidence of post-herpetic neuralgia (PHN). PMID:27800502

  14. Evasion of Early Antiviral Responses by Herpes Simplex Viruses

    Science.gov (United States)

    Suazo, Paula A.; Ibañez, Francisco J.; Retamal-Díaz, Angello R.; Paz-Fiblas, Marysol V.; Bueno, Susan M.; Kalergis, Alexis M.; González, Pablo A.

    2015-01-01

    Besides overcoming physical constraints, such as extreme temperatures, reduced humidity, elevated pressure, and natural predators, human pathogens further need to overcome an arsenal of antimicrobial components evolved by the host to limit infection, replication and optimally, reinfection. Herpes simplex virus-1 (HSV-1) and herpes simplex virus-2 (HSV-2) infect humans at a high frequency and persist within the host for life by establishing latency in neurons. To gain access to these cells, herpes simplex viruses (HSVs) must replicate and block immediate host antiviral responses elicited by epithelial cells and innate immune components early after infection. During these processes, infected and noninfected neighboring cells, as well as tissue-resident and patrolling immune cells, will sense viral components and cell-associated danger signals and secrete soluble mediators. While type-I interferons aim at limiting virus spread, cytokines and chemokines will modulate resident and incoming immune cells. In this paper, we discuss recent findings relative to the early steps taking place during HSV infection and replication. Further, we discuss how HSVs evade detection by host cells and the molecular mechanisms evolved by these viruses to circumvent early antiviral mechanisms, ultimately leading to neuron infection and the establishment of latency. PMID:25918478

  15. Reactivation of herpes simplex virus-1 following epilepsy surgery☆

    Science.gov (United States)

    de Almeida, Sérgio Monteiro; Crippa, Ana; Cruz, Cristina; de Paola, Luciano; de Souza, Luciana Paula; Noronha, Lucia; Torres, Luis Fernando Bleggi; Koneski, Julio A.S.; Pessa, Luis Felipe Cavalli; Nogueira, Meri Bordignon; Raboni, Sonia Mara; Silvado, Carlos Eduardo; Vidal, Luine Rosele

    2015-01-01

    Purpose The present study reports a case of encephalitis due to herpes simplex virus-1 (HSV-1), following surgical manipulation of the site of a primary infection. Methods Herpes simplex virus-1 infection was confirmed by CSF PCR and DNA sequencing. Results The patient was an 11-year-old girl who required temporal lobe surgery for epilepsy. She had meningoencephalitis due to HSV at the age of 20 months, and she was treated with acyclovir. Three years later, the patient developed uncontrolled seizures that became more frequent and changed in character at 11 years of age. On the 12th postoperative day, she developed fever and seizures, and she was diagnosed with HSV-1 by positive CSF PCR. She was treated with acyclovir (30 mg/kg/day for 21 days). In this report, we describe the patient and review the relevant literature. Conclusion The authors stress the potential risk of reactivation of HSV encephalitis after intracranial surgery. Herpes simplex virus encephalitis must be considered in neurosurgical patients who develop postoperative seizures and fever. PMID:26543809

  16. Prophylactic Antiviral Treatment in Recurrent Herpes Zoster: A Case Report

    Directory of Open Access Journals (Sweden)

    Hatice Gamze Bayram

    2011-06-01

    Full Text Available Herpes zoster (HZ occurs in older ages with activation of varicella-zoster virus (VZV which persists in a dormant phase within the dorsal root ganglia. The incidence of HZ in immunosuppressed patients is 20-100 times higher and the clinical progress is more severe than in immunocompetent individuals. A 48-year-old man who had been diagnosed with acute myelocytic leukemia type M3 and had been treated with immunosuppressive agents was admitted to our clinic. The patient was clinically diagnosed as having HZ. He was treated with acyclovir 800 mg five times daily for 7 days. In the consecutive three months, he attended our clinic again with similar complaints. The left cervical (C5, C6 dermatomes were involved at the fourth attack of HZ. Multinucleated giant cells were determined on the Tzanck smear. VZV DNA was detected by polymerase chain reaction (PCR. Treatment with valacyclovir 1 g three times daily for 14 days was prescribed and then, prophylactic treatment with valacyclovir 500 mg two times a day was administered. Although immunosuppressive treatment was continued, no new attacks of herpes zoster occurred. We think that prophylactic antiviral therapy should be initiated in immunosuppressive individuals who have recurrent herpes zoster attacks.

  17. Seronegative Herpes simplex Associated Esophagogastric Ulcer after Liver Transplantation

    Directory of Open Access Journals (Sweden)

    Edouard Matevossian

    2008-03-01

    Full Text Available Herpes simplex infection is characterized by acute or subacute infection, often followed by a chronic carrier state. Consecutive recurrences may flare up if immunocompromise occurs. Herpes simplex associated esophagitis or duodenal ulcer have been reported in immunocompromised patients due to neoplasm, HIV/AIDS or therapeutically induced immune deficiency. Here we report the case of an HSV-DNA seronegative patient who developed grade III dysphagia 13 days after allogeneic liver transplantation. Endoscopy revealed an esophageal-gastric ulcer, and biopsy histopathology showed a distinct fibroplastic and capillary ulcer pattern highly suspicious for viral infection. Immunohistochemistry staining revealed a distinct nuclear positive anti-HSV reaction. Antiviral therapy with acyclovir and high-dose PPI led to a complete revision of clinical symptoms within 48 h. Repeat control endoscopy after 7 days showed complete healing of the former ulcer site at the gastroesophageal junction. Although the incidence of post-transplantation Herpes simplex induced gastroesophageal disease is low, the viral HSV ulcer may be included into a differential diagnosis if dysphagia occurs after transplantation even if HSV-DNA PCR is negative.

  18. Neuropsychologic outcomes in children with neonatal herpes encephalitis.

    Science.gov (United States)

    Engman, Mona-Lisa; Adolfsson, Ingrid; Lewensohn-Fuchs, Ilona; Forsgren, Marianne; Mosskin, Mikael; Malm, Gunilla

    2008-06-01

    Neonatal herpes simplex virus infection with involvement of the central nervous system is a serious disease with high morbidity, even with acyclovir therapy. The disability includes cerebral palsy and different aspects of cognitive dysfunction which are of utmost importance for the child's future habilitation. We conducted a descriptive cohort study to define neuropsychologic outcomes and determine the relationship between neonatal neuroimaging and neuropsychologic outcomes. Among 267,690 children born in the Stockholm area over 12 years (1989-2000), 14 were diagnosed with neonatal herpes including central nervous system involvement. Nine children were neuropsychologically evaluated. Neonatal herpes virus infection had an even greater impact on cognitive function, speech ability, and attention deficit than anticipated. Relapse leading to deterioration was demonstrated in one child. Social skills were influenced to a lesser degree. Neurodevelopmental outcomes of the children were not well-correlated with extent of cerebral damage as visualized by computed tomography at 7-28 days after onset of signs. Neuropsychologic assessment is essential in the habilitation of the child, and a prerequisite for the evaluation of new treatments and for the assessment of deterioration of cerebral function related to relapses.

  19. Linfoma canino de células T: aspectos epidemiológicos, clínicos e morfológicos de 38 casos

    Directory of Open Access Journals (Sweden)

    Kleber Moreno

    2007-12-01

    Full Text Available O objetivo deste trabalho foi avaliar a ocorrência e aspectos clínicos, morfológicos e imunoistoquímicos de linfomas caninos de células T. Foram avaliados 71 cães com linfoma, dos quais 38 foram classificados imunoistoquimicamente como células T. Conforme a classificação da Working Formulation e Kiel 18 foram classificados como grau intermediário de malignidade, 15 de alta malignidade e 5 de baixa malignidade. O padrão de proliferação linfomatoso foi difuso em todos os animais (38. O linfoma de células T foi mais comum em cães de raça definida (24/38, como Boxer, Cocker Spaniel Inglês e Rottweiler. A ocorrência de linfoma T em machos (21/38 foi maior do que em fêmeas e a idade média foi de 5,8 anos (1-13 anos. Quanto à classificação anatômica e estadiamento clínico do linfoma de células T, a forma multicêntrica (29/38 foi a mais comum e os estádios IV (15/38 e III (14/38, respectivamente.

  20. Efeito do soro de cadela em estro na maturação in vitro de ovócitos caninos

    Directory of Open Access Journals (Sweden)

    C.A.N Goretti

    2011-10-01

    Full Text Available Avaliou-se o efeito do soro de cadela em estro na maturação in vitro de ovócitos caninos, utilizando-se 92 ovócitos de cadelas, submetidas à cirurgia eletiva de ovarioisterectomia. Os ovócitos foram selecionados e distribuídos em dois tratamentos: T1 (n = 48, ovócitos cultivados in vitro durante 96 horas utilizando meio base - TCM199 + 5µg/mL de LH + 20µg/mL de FSH - mais 10% de soro inativado de vaca em estro e T2 (n = 44, ovócitos cultivados em meio base mais 10% de soro inativado de cadela em estro. O percentual de ovócitos observados em metáfase I não indicou diferenças (P>0,05 entre T1 (2,1% e T2 (0,0%, porém a taxa de ovócitos maduros (metáfase II foi diferente (P0,05, sendo 56,3% em T1 e 52,3% em T2. Estes resultados indicam que a adição de soro de cadela em estro no meio de cultivo oferece melhores condições para o desenvolvimento in vitro, quando comparado à de soro de vaca em estro.

  1. Estimativa do intervalo pós-morte em um canino (Canis lupus familiaris Linnaeus 1758 pela entomologia forense em Cabedelo-PB, Brasil: relato de caso

    Directory of Open Access Journals (Sweden)

    G. Martins

    2013-08-01

    Full Text Available O intervalo pós-morte (IPM é um instrumento importante de diagnóstico relacionado à prática forense. O uso de insetos tem sido relatado como um modo eficiente para estimá-lo, quando o cadáver encontra-se em estágio avançado de decomposição. Objetivou-se com este trabalho estimar o IPM com base em evidências entomológicas em um canino. Foram coletadas larvas de moscas no cadáver e encaminhadas ao laboratório de entomologia, onde foram criadas e eclodiram adultos da espécie Chrysomya albiceps (Wiedemann, 1819. Somando-se os dados abióticos de temperatura e umidade relativa do local de coleta e do local de criação, estimou-se um IPM mínimo de 3,34 dias do momento da postura dos ovos pelas moscas até a coleta das larvas. Com base nos resultados obtidos, conclui-se que a entomologia forense, como ferramenta para estimativa do IPM, mostrou-se eficaz e determinante na elucidação do caso em questão.

  2. Estereótipos e mulheres na cultura marroquina

    OpenAIRE

    Sadiqi,Fatima

    2008-01-01

    Estereótipos sobre as mulheres no Marrocos podem ser caracterizados como crenças culturais incompletas e inexatas mantidas por algumas pessoas e que se encontram inscritos em expressões lingüísticas ou em discursos subliminares. A cultura popular marroquina emprega representações poderosas para transmitir e sustentar tais estereótipos. Embora existam alguns estereótipos positivos, a maioria dos estereótipos sobre as mulheres no Marrocos é negativa e reflete ditames patriarcais subliminares qu...

  3. Distrofia simpática reflexa pós herpes zoster Reflex sympathetic dystrophy following herpes zoster

    Directory of Open Access Journals (Sweden)

    Catia Susana Harumi Minami

    2004-08-01

    Full Text Available A distrofia simpática reflexa (DSR é uma síndrome dolorosa pouco entendida que consiste na presença de múltiplos sinais e sintomas incluindo dor, edema, alterações cutâneas distróficas e disfunção autonômica envolvendo uma ou mais extremidades. Nem sempre a DSR pós-herpes zóster é facilmente reconhecida. Poucos relatos dessa complicação foram publicados, o que torna interessante esta descrição. Apresentamos o caso de uma mulher branca, de 65 anos de idade cujos sinais e sintomas característicos de DSR no membro superior direito surgiram após 4 semanas do aparecimento das lesões de herpes zóster envolvendo trajeto dermatomérico. Com o diagnóstico precoce e abordagem terapêutica com calcitonina nasal e fisioterapia houve melhoras funcional e álgica satisfatórias em um mês de tratamento.The reflex sympathetic dystrophy (RSD is a poorly understood, painful syndrome that consists of multiple clinical manifestations, including pain, swelling, dystrophic cutaneous changes and autonomic dysfunction involving one or more extremities. The RSD following herpes zoster is not always easily recognized, and only a few documented cases of this complication have been reported, what makes this report even more interesting. We present the case of a 65 years old white woman, with characteristic signs and symptoms of RSD in the right upper limb observed four weeks after she had had a typical herpes zoster involving the dermatomes. Early diagnosis and treatment with intranasal calcitonin and physiotherapy lead to progressive functional and pain improvements after one month.

  4. Utilidad de la goniometría en la evaluación del rango de los movimientos de flexión y extensión de la articulación del codo canino The useful of goniometry to evaluate the range of the elbow flexion and extension in dogs

    OpenAIRE

    M. C. MERCADO; M Gambarotta; S. González; Pallares, C

    2008-01-01

    La goniometría es una técnica muy utilizada en Kinesiología Humana para evaluar ángulos articulares. Los autores realizaron este trabajo con el objetivo de poder establecer si es tan útil en Medicina veterinaria para evaluar funcionalidad articular. Se eligió la articulación del codo canino debido a su complejidad. Fueron seleccionados 24 pacientes caninos derivados al Servicio de Fisioterapia del Hospital Escuela de la Facultad de Ciencias Veterinarias, Universidad de Buenos Aires, Argentina...

  5. Chloroquine diphosphate: a risk factor for herpes zoster in patients with dermatomyositis/polymyositis

    Directory of Open Access Journals (Sweden)

    Gilmara Franco da Cunha

    2013-05-01

    Full Text Available OBJECTIVES: Herpes zoster has been widely described in the context of different systemic autoimmune diseases but not dermatomyositis/polymyositis. Therefore, we analyzed the prevalence, risk factors and herpes zoster outcomes in this population. METHOD: A retrospective cohort study of herpes zoster infections in dermatomyositis/polymyositis patients was performed. The patients were followed at a tertiary center from 1991 to 2012. For the control group, each patient with herpes zoster was paired with two patients without herpes zoster. Patients were matched by gender and the type of myositis, age at myositis onset and disease duration. RESULTS: Of 230 patients, 24 (10.4% had a histories of herpes zoster (19 with dermatomyositis and five with polymyositis, two-thirds female. The mean age of the patients with herpes zoster was 44.6±16.8 years. No difference between the groups was found regarding cumulative clinical manifestations. Disease activity, autoantibody, muscle and leukogram parameters were also comparable between the groups. No differences in immunosuppressive (alone or in association with other immunosuppressive therapies or glucocorticoid (current use, medium dose and cumulative dose in the last two months therapies were found between patients with and without herpes zoster. However, a higher proportion of patients in the herpes zoster group received chloroquine diphosphate compared to the control group. All of the patients received acyclovir; 58.3% of patients had postherpetic neuralgia and no cases of recurrence were reported. Furthermore, individuals who were taking high prednisone doses at the time of the herpes zoster diagnosis had reduced levels of postherpetic neuralgia. CONCLUSIONS: These data suggest that chloroquine diphosphate could predispose patients with dermatomyositis/polymyositis to developing herpes zoster, particularly women and dermatomyositis patients.

  6. Herpes zoster vaccine effectiveness and manifestations of herpes zoster and associated pain by vaccination status

    Science.gov (United States)

    Marin, Mona; Yawn, Barbara P; Hales, Craig M; Wollan, Peter C; Bialek, Stephanie R; Zhang, John; Kurland, Marge J; Harpaz, Rafael

    2015-01-01

    Options for managing herpes zoster (HZ)-related pain and complications have limited effectiveness, making HZ prevention through vaccination an important strategy. Limited data are available on HZ vaccine effectiveness against confirmed HZ and manifestations of HZ among vaccinated persons. We conducted a matched case-control study to assess HZ vaccine effectiveness for prevention of HZ and other HZ-related outcomes and a cohort study of persons with HZ to compare HZ-related outcomes by vaccination status. Cases were identified through active surveillance among persons age ≥60 years with HZ onset and health-care encounters during 2010-2011 in Southeastern Minnesota. Controls were age- and sex-matched to cases. Data were collected by medical record review and from participants via interviews and daily pain diaries. 266 HZ case-patients and 362 matched controls were enrolled in the vaccine effectiveness studies and 303 case-patients in the cohort study of HZ characteristics by vaccination status. Vaccination was associated with 54% (95% CI:32%-69%) reduction in HZ incidence, 58% (95% CI:31%-75%) reduction in HZ prodromal symptoms, and 70% (95% CI:33%-87%) reduction in medically-attended prodrome. HZ vaccine was statistically significant effective at preventing postherpetic neuralgia (PHN) measured at 30 d after rash onset, 61% (95% CI: 22%-80%). Among persons who developed HZ, no differences were found by vaccination status in severity or duration of HZ pain after rash onset. In this population-based study, HZ vaccination was associated with >50% reduction in HZ, HZ prodrome, and medically-attended prodrome. PMID:25806911

  7. Serologic Screening for Herpes Simplex Virus among University Students: A Pilot Study

    Science.gov (United States)

    Mark, Hayley; Nanda, Joy P.; Joffe, Alain; Roberts, Jessica; Rompalo, Anne; Melendez, Johan; Zenilman, Jonathan

    2008-01-01

    Objective: The authors examined the feasibility of conducting serologic testing for the herpes simplex virus 2 (HSV-2) among university students and assessed the psychosocial impact of an HSV-2 diagnosis. Methods: The authors recruited a convenience sample of 100 students (aged 18-39 years) without a history of genital herpes from 1 university…

  8. [Role of herpes simplex virus in the development of exudative erythema multiforme].

    Science.gov (United States)

    Samgin, M A; Ivanov, O L; Kuzheleva, S A; Biriukov, A V; L'vov, N D

    1990-03-01

    The paper presents analysis of current knowledge on etiology and immunopathogenesis of multiform exudative erythema (MEE). Among a variety of pathogenetic actions of herpes simplex on immune system are those relevant to MEE onset. These variants are dealt with in detail. The view on MEE as resultant from herpes simplex infection promises appearance of new prospective modes of etiotropic therapy.

  9. On the Issue of Herpes Infection as an Actual Problem Nowadays

    Directory of Open Access Journals (Sweden)

    V.P. Borak

    2016-04-01

    Full Text Available Among persistent intracellular agents, a group of herpesviruses occupies the leading place after the prevalence. The World Health Organization (WHO warns the international community of the danger of latent herpes infection pandemic. According to the WHO, 70 to 90 % of the world population is infected with one or more types of herpes virus, and in 50 % of them, due to the absence of stable immunity, disease relapses occur annually. The family of herpes viruses found in humans includes herpes simplex virus type 1 and 2, Zoster virus, cytomegalovirus, Epstein-Barr virus, human herpes type 6, 7, 8. Thus, in the pathogenesis of herpes infection type 1 and 2, there are four main phases: the penetration of the epithelial cells → penetration into the nerve endings and paravertebral ganglia → elimination of the virus from tissues and organs → reactivation of herpes simplex virus and moving it to the port of infection. Herpetic and cytomegalovirus infection that belongs to the group of TORCH infections is the most common cause fetal infection, which can lead to the birth of a child with disabilities. Herpesvirus infections are considered as a group of infections associated with human immunodeficiency syndrome, and is a common cause of damage to the central nervous system and internal organs in patients with secondary immunodeficiency. Almost all known now human herpesviruses can cause damage to the nervous system. In this regard, herpes infections have become one of the leading medical and social problems and acquire national importance.

  10. [Post-herpes simplex encephalitis chorea: Viral replication or immunological mechanism?].

    Science.gov (United States)

    Benrhouma, H; Nasri, A; Kraoua, I; Klaa, H; Turki, I; Gouider-Khouja, N

    2015-09-01

    Herpes simplex encephalitis is a severe neurological condition, whose outcome is improved if treated early with acyclovir. Post-herpes simplex encephalitis with acute chorea has rarely been reported. We report on two observations of children presenting with post-herpes simplex encephalitis with acute chorea, related to two different pathophysiological mechanisms. The first one is an 11-month-old girl developing relapsing herpes simplex encephalitis with chorea due to resumption of viral replication. The second one is a 2-year-old boy with relapsing post-herpes simplex encephalitis acute chorea caused by an immunoinflammatory mechanism. We discuss the different neurological presentations of herpetic relapses, notably those presenting with movement disorders, as well as their clinical, paraclinical, physiopathological, and therapeutic aspects. Post-herpes simplex encephalitis with acute chorea may involve two mechanisms: resumption of viral replication or an immunoinflammatory mechanism. Treatment of post-herpes simplex encephalitis with acute chorea depends on the underlying mechanism, while prevention is based on antiviral treatment of herpes simplex encephalitis with acyclovir at the dose of 20mg/kg/8h for 21 days. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

  11. Incidence of Herpes Zoster in relationship with Climate Factors from 2009 to 2011

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    Herning Adinda

    2015-09-01

    Full Text Available Background: Herpes zoster, or shingles, is a skin or mucous infection caused by the reactivation of varicella-zoster virus (VZV. Seasonal pattern of herpes zoster incidence was reported in some countries, indicating that emergence of this disease was caused by the reactivation of latent Varicella-Zoster Virus (VZV rather than new exposures to VZV. On the other hand, the VZV primary infection difference between tropical and temperate zones may have implications for virus reactivation as herpes zoster. The aim of this study was to identify the incidence of herpes zoster in Dr. Hasan Sadikin General Hospital Bandung, West Java related to the change of rainfall, air temperature and humidity from 2009 to 2011. Methods: A descriptive retrospective study was carried out to 341 medical records of herpes zoster patients from Dr. Hasan Sadikin General Hospital Bandung periode 2009 to 2011. Data on climate factors, i.e. rainfall, air temperature, and relative humidity, were obtained from the Indonesian Meteorology, Climatology, and Geophysical Agency. The collected data were presented using tables and figures. Result: The highest number of herpes zoster cases occured during the period when the highest annually total rainfall and annually mean relative humidity occurred. Conclusions: The finding of this study shows that herpes zoster cases have the same pattern with the rainfall and relative humidity. These findings can inform better prevention of herpes zoster. However, further research is needed to get more comprehensive understanding on this relationship.

  12. CLINICAL AND VIROLOGIC FOUNDATION FOR PATHOGENETIC THERAPY OF HUMAN HERPES VIRUS TYPE 6 INFECTION IN CHILDREN

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    N.A. Myukke

    2006-01-01

    Full Text Available Information about an infection caused by human herpes virus type 6, its' epidemiology, pathogenesis and clinical variants, is reviewed. Clinical cases, diagnosed at a time of study, are briefly reviewed.Key words: human herpes virus type 6, exanthema subitum (roseola infantum, fever of unknown origin, mononucleosis like syndrome, meningoencephalitis, children.

  13. [Syphilis in a patient with the primary diagnosis of infectious mononucleosis, cytomegalovirus and herpes infection].

    Science.gov (United States)

    Bogomolov, B P; Sorokina, A A; Koroleva, m A

    2014-01-01

    The paper reports a case of fresh secondary syphilis affecting oral cavity and lips in a 25 year old woman. The primary diagnosis of infectious mononucleosis, cytomegalovirus and herpes infection proved erroneous. Retrospective differential diagnostics of infectious mononucleosis, cytomegalovirus and herpes infection from fresh secondary syphilis was performed This case suggests the absence of vigilance with respect to venereal diseases in the medical personnel.

  14. Cesarean Delivery in Women With Genital Herpes in Washington State, 1989–1991

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    Jeanne M. Marrazzo

    1997-01-01

    Full Text Available Objective: The purpose of this study was to determine whether the proportion of cesarean deliveries in pregnant women with a history of genital herpes and no active lesions at birth is higher than that in women with no history of genital herpes, and to determine whether this risk was modified by birth facilities' underlying prevalence of cesarean delivery.

  15. Laboratory diagnosis and epidemiology of herpes simplex 1 and 2 genital infections.

    Science.gov (United States)

    Glinšek Biškup, Urška; Uršič, Tina; Petrovec, Miroslav

    2015-01-01

    Herpes simplex virus types 1 and 2 are the main cause of genital ulcers worldwide. Although herpes simplex virus type 2 is the major cause of genital lesions, herpes simplex virus type 1 accounts for half of new cases in developed countries. Herpes simplex virus type 2 seroprevalence rises with sexual activity from adolescence through adulthood. Slovenian data in a high-risk population shows 16% seroprevalence of HSV-2. HSV-1 and HSV-2 DNA in genital swabs was detected in 19% and 20.7%, respectively. In most cases, genital herpes is asymptomatic. Primary genital infection with herpes simplex virus types 1 and 2 can be manifested by a severe clinical picture, involving the vesicular skin and mucosal changes and ulcerative lesions of the vulva, vagina, and cervix in women and in the genital region in men. Direct methods of viral genome detection are recommended in the acute stage of primary and recurrent infections when manifest ulcers or lesions are evident. Serological testing is recommended as an aid in diagnosing genital herpes in patients with reinfection in atypical or already healed lesions. When herpes lesions are present, all sexual activities should be avoided to prevent transmission of infection. Antiviral drugs can reduce viral shedding and thus reduce the risk of sexual transmission of the virus.

  16. Reduced NK cell IFN-γ secretion and psychological stress are independently associated with herpes zoster.

    Science.gov (United States)

    Kim, Choon Kwan; Choi, Youn Mi; Bae, Eunsin; Jue, Mihn Sook; So, Hyung Seok; Hwang, Eung-Soo

    2018-01-01

    The pathogenesis of herpes zoster is closely linked to reduced varicella-zoster virus-specific cell-mediated immunity. However, little is known about the interplay between natural killer cells and psychological stress in the pathogenesis of herpes zoster. This study aimed to investigate possible associations among natural killer cells, T cells and psychological stress in herpes zoster. Interferon-gamma secretion from natural killer cell, psychological stress events, stress cognition scale scores and cytomegalovirus-specific cell-mediated immunity were compared between 44 patients with herpes zoster and 44 age- and gender-matched control subjects. A significantly lower median level of interferon-gamma secreted by natural killer cells was observed in patients with a recent diagnosis of herpes zoster than in control subjects (582.7 pg/ml vs. 1783 pg/ml; P = 0.004), whereas cytomegalovirus-specific cell-mediated immunity was not associated with herpes zoster. Psychological stress events and high stress cognition scale scores were significantly associated in patients with herpes zoster (Pherpes zoster display reduced interferon-gamma secretion from natural killer cells and frequent previous psychological stress events compared with controls. However, reduced natural killer cell activity is not an immunological mediator between psychological stress and herpes zoster.

  17. Study of Herpes Zoster in a Self-Referral Out-Patient Clinic ...

    African Journals Online (AJOL)

    Aim: To study the presentation of herpes zoster (shingles) in self-referral urban primary care setting. Patients and method: During nearly 20 years, patients of Igbo ethnic group presented with herpes zoster, on a self-referral basis, to my urban, week day evening, out patient clinic. The recorded epidemiological parameters ...

  18. Detection of Human Herpes Virus 8 in Kaposi's sarcoma tissues at ...

    African Journals Online (AJOL)

    Introduction: Human herpes virus-8, a γ2-herpes virus, is the aetiological agent of Kaposi sarcoma. Recently, Kaposi's sarcoma cases have increased in Zambia. However, the diagnosis of this disease is based on morphological appearance of affected tissues using histological techniques, and the association with its ...

  19. Herpes zoster-associeret morbiditet hos børn i kemoterapi for akut lymfoblastaer leukaemi

    DEFF Research Database (Denmark)

    Sørensen, Gitte Vrelits; Helgestad, Jon; Rosthøj, Steen

    2009-01-01

    INTRODUCTION: Herpes zoster rarely occurs in healthy children, but may occur frequently and may take a complicated course in children receiving chemotherapy. We aimed to assess morbidity from herpes zoster in children with acute lymphoblastic leukemia (ALL). MATERIAL AND METHODS: Reviewing records...

  20. Analysis of contributions of herpes simplex virus type 1 UL43 protein ...

    African Journals Online (AJOL)

    system implemented on the Herpes simplex virus 1 (HSV-1) bacterial artificial chromosome (BAC). ... UL43 gene of HSV-1 encodes a non- glycosylated transmembrane protein which is conserved only in alpha- and gamma herpes viruses [8]. The HSV-1 UL43 has been ... AG-3'), which mutates the initiation codon from.

  1. Comprometimento medular por linfoma tipo Burkitt: relato de um caso

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    Murillo Côrtes Drummond

    1985-06-01

    Full Text Available Registro de caso de linfoma tipo Burkitt com comprometimento intrarraqueano em criança de três anos de idade. Considerações sobre esse tipo de tumor são feitas em função do caso observado e de dados da literatura.

  2. Reporte de un caso clínico Técnica quirúrgica combinada de omentalización y drenaje transabdominal múltiple en un paciente canino con abscesos prostáticos

    OpenAIRE

    Diego Fernando Echeverry Bonilla; Edwin Fernando Buriticá Gaviria

    2006-01-01

    Se expone el caso clínico de un paciente canino mestizo de 7 años de edad, que fue presentado a consulta médica en la clínica de Pequeños Animales de la Facultad de Medicina Veterinaria y Zootecnia de la Universidad del Tolima, por presentar un cuadro clínico consistente en: polaquiuria, disuria, tenesmo, fiebre, pérdida ponderal. La información obtenida a partir de la anamnesis, examen físico y estudios paraclínicos permitieron diagnosticar abscesos prostáticos, el tratamiento quirúrgico con...

  3. Herpes labialis manifesting as recurrent erythema multiforme and solitary ulcer on face

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    Biju Vasudevan

    2009-01-01

    Full Text Available A 65-year-old lady presented with recurrent crusting of lips and ulceration on face since the last three weeks. History revealed recurrent herpes labialis during the previous three years. Examination showed hemorrhagic crusting of lips and a solitary crusted ulcer on the right cheek. The patient showed partial improvement with antiviral therapy. On withdrawal of initial therapy, the patient developed classical lesions of herpes labialis and erythema multiforme. Investigations confirmed herpes simplex infection and erythema multiforme. All the lesions including the ulcer on the face responded to maintenance therapy with antivirals. Though herpes infection has been found to cause ulcers especially in the peri-anal region in immunosuppressed individuals, it is the first time in literature that a facial ulcer has been ascribed to herpes simplex virus that too in an immunocompetent individual.

  4. Relação da expressão de fatores de crescimento celular (IGF-1 e (SCF com fatores prognósticos e o alvo da rapamicina em mamíferos (m-TOR em mastocitomas cutâneos caninos

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    Raquel B. Ferioli

    2013-04-01

    Full Text Available O mastocitoma cutâneo (MTC é a neoplasia maligna mais comum na pele dos cães e seu comportamento biológico é muito variável. Dentre os fatores prognósticos estudados nos MTCs, a classificação histopatológica, o índice proliferativo e o padrão de expressão doc-KIT são os que apresentam uma associação mais relevante com o provável prognóstico deste tumor. O objetivo deste trabalho foi avaliar a expressão proteica de fator de crescimento semelhante à insulina tipo 1 (IGF-1, fator de célula tronco (SCF e sua relação com o receptor tirosina quinase (c-KIT, alvo da rapamicina em mamíferos (m-TOR, grau histológico, índice proliferativo pelo KI-67e o número de figuras de mitose (IM com dados clínicos de cães com MTCs . Foram utilizadas 133 amostras de MTCs, provenientes de 133 cães, dispostas em lâminas de microarranjo de tecidos (TMA. A técnica de imuno-histoquímica foi utilizada para a avaliação destas proteínas. Observou-se associação entre SCF e, a graduação histopatológica proposta em 2011, índice mitótico, proliferação celular (KI-67, escore de IGF-1, local da lesão, idade dos animais e padrão imuno-histoquímico do receptor c-KIT. A relação de dependência também foi observada entre IGF-1 e o porte dos animais, IM, m-TOR e c-KIT. A expressão de SCF teve relacção com a agressividade dos MTCs caninos, uma vez que foi mais freqüente em MTCs com c-KIT citoplasmático. A relação entre a expressão de IGF-1, SCF, c-KIT e m-TOR pode estar associada à integralização de suas vias de ação. A expressão de IGF-1 está associada à MTCs em cães de porte grande.

  5. RNA interference inhibits herpes simplex virus type 1 isolated from saliva samples and mucocutaneous lesions.

    Science.gov (United States)

    Silva, Amanda Perse da; Lopes, Juliana Freitas; Paula, Vanessa Salete de

    2014-01-01

    The aim of this study was to evaluate the use of RNA interference to inhibit herpes simplex virus type-1 replication in vitro. For herpes simplex virus type-1 gene silencing, three different small interfering RNAs (siRNAs) targeting the herpes simplex virus type-1 UL39 gene (sequence si-UL 39-1, si-UL 39-2, and si-UL 39-3) were used, which encode the large subunit of ribonucleotide reductase, an essential enzyme for DNA synthesis. Herpes simplex virus type-1 was isolated from saliva samples and mucocutaneous lesions from infected patients. All mucocutaneous lesions' samples were positive for herpes simplex virus type-1 by real-time PCR and by virus isolation; all herpes simplex virus type-1 from saliva samples were positive by real-time PCR and 50% were positive by virus isolation. The levels of herpes simplex virus type-1 DNA remaining after siRNA treatment were assessed by real-time PCR, whose results demonstrated that the effect of siRNAs on gene expression depends on siRNA concentration. The three siRNA sequences used were able to inhibit viral replication, assessed by real-time PCR and plaque assays and among them, the sequence si-UL 39-1 was the most effective. This sequence inhibited 99% of herpes simplex virus type-1 replication. The results demonstrate that silencing herpes simplex virus type-1 UL39 expression by siRNAs effectively inhibits herpes simplex virus type-1 replication, suggesting that siRNA based antiviral strategy may be a potential therapeutic alternative. Copyright © 2014. Published by Elsevier Editora Ltda.

  6. Herpes Zoster and Dementia: A Nationwide Population-Based Cohort Study.

    Science.gov (United States)

    Chen, Vincent Chin-Hung; Wu, Shu-I; Huang, Kuo-You; Yang, Yao-Hsu; Kuo, Ting-Yu; Liang, Hsin-Yi; Huang, Kuan-Lun; Gossop, Michael

    2017-12-12

    Some infectious diseases have been found to be associated with cognitive impairment and dementia. However, the relationship between herpes zoster and dementia has received little attention. This study aimed to investigate this association as well as associations of antiviral treatments for herpes zoster and incident dementia using a large national sample. Cases were identified from the Taiwan National Health Insurance Research Database with a new diagnosis of herpes zoster (ICD-9-CM code: 053) between 1997 and 2013. Each identified individual with a case of herpes zoster was compared with 1 sex-, age-, and residence-matched control subject. Both groups were followed until the first diagnosis of dementia (ICD-9-CM codes: 290.0 to 290.4, 294.1, 331.0 to 331.2, and 331.82), withdrawal from the registry, or the end of 2013. Cox regression analyses and competing risk model were applied, adjusting for sex, age, residence, depression, autoimmune disease, ischemic stroke, traumatic brain injury, alcohol use disorder, and antiviral treatments for herpes zoster to evaluate the risk of interest. A total of 39,205 cases with herpes zoster were identified. Of the 78,410 study and comparison subjects, 4,204 were diagnosed as having dementia during a mean (SD) follow-up period of 6.22 (4.05) years. Herpes zoster was associated with a slightly increased risk of dementia in the fully adjusted model (hazard ratio [HR] = 1.11; 95% CI, 1.04-1.17). Prescriptions of antiviral therapy were associated with a reduced risk of developing dementia following the diagnosis of herpes zoster (HR = 0.55; 95% CI, 0.40-0.77). Herpes zoster was associated with an increased risk of dementia, independent of potential confounding factors. Antiviral treatment might be protective in preventing dementia in patients with herpes zoster.

  7. Update on Neonatal Herpes Simplex Epidemiology in the Netherlands: A Health Problem of Increasing Concern?

    Science.gov (United States)

    van Oeffelen, Louise; Biekram, Manisha; Poeran, Jashvant; Hukkelhoven, Chantal; Galjaard, Sander; van der Meijden, Wim; Op de Coul, Eline

    2018-01-18

    This paper provides an update on the incidence of neonatal herpes, guideline adherence by health care professionals (HCP), and trends in genital herpes simplex virus (HSV) infection during pregnancy in the Netherlands. Questionnaires were sent to all hospitals inquiring about numbers and characteristics of neonatal and maternal HSV infections, and guideline adherence between 2012 and 2015. Longitudinal trends were investigated from 1999 onwards using survey data and Perinatal Registry of the Netherlands data (Perined). Trends were smoothed with Poisson regression splines. Risk indicators for neonatal and maternal HSV infections were examined with Poisson regression analyses. Neonatal herpes incidence was 4.8/100,000 live births based on survey data (2012-2015) and 3.4/100,000 based on Perined (2012-2014). Mortality rate was 23% (7/30). Neonatal herpes incidence increased slightly over time as did the prevalence of genital HSV infection among pregnant women. Non-Western ethnicity (RR 1.9, 95%CI 1.5-2.5) and age herpes during pregnancy. In Perined, none of the neonatal herpes cases had a mother diagnosed with an active genital herpes infection during pregnancy. Preventive measures to reduce vertical herpes transmission (such as caesarean section) were less commonly reported by HCP in 2012-2015 compared to 2006-2011. Neonatal herpes incidence in the Netherlands slowly increased over the last 15 years. An increased genital HSV prevalence during pregnancy or, to lower extent, the decreased guideline adherence by HCP may be responsible. A rise in asymptomatic maternal HSV shedding is also plausible, emphasizing the challenges in preventing neonatal herpes.

  8. Lesao óssea em leucemias agudas linfoblásticas tipo T e TIPO nao T / nao B

    OpenAIRE

    Martins, Fernando Lopes

    2013-01-01

    Resumo: O AUTOR APRESENTA OS RESULTADOS DO ESTUDO RADIOLÓGICO DE ESQUELETO DE 61 PACIENTES PORTADORES DE LEUCEMIA AGUDA LINFOBLÁSTICA, CORRELACIONANDO A PRESENÇA OU NÃO DE Lesões ÓSSEAS COM A CLASSIFICAÇÃO IMUNOLÓGICA DE LAL TIPO T E TIPO não T / não B

  9. Evaluation of the HerpeSelect Express rapid test in the detection of herpes simplex virus type 2 antibodies in patients with genital ulcer disease.

    Science.gov (United States)

    Al-Shobaili, Hani; Hassanein, Khaled M; Mostafa, Marwa Salah; Al Duways, Ali Saleh

    2015-01-01

    A rapid point-of-care test with high sensitivity and specificity is required in order to fulfill the need for early detection and screening of Herpes simplex virus type 2 (HSV-2) infection among patients with genital ulcer disease (GUD), for better management and control of virus transmission. The goal of this study is to evaluate the performance of the commercially available HerpeSelect Express rapid test in comparison with three ELISA assays: HerpeSelect ELISA, Kalon HSV-2 glycoprotein G2 assay, and monoclonal antibody blocking enzyme immunoassay, which was used as the gold standard for the detection of HSV-2 antibodies. This study showed high sensitivity (ranging from 82.6 to 100%) and specificity (100%) of the HerpeSelect Express rapid test when compared to the three ELISA assays. The agreement between the HerpeSelect Express rapid test with the three ELISAs ranged from 93.3 to 100%. The HerpeSelect Express rapid test has adequate sensitivity and specificity for confirming HSV-2 infection in patients with GUD, indicating its suitability for epidemiological studies. © 2014 Wiley Periodicals, Inc.

  10. Aurotriquia adquirida em um canino da raça schnauzer Acquired aurotriquia in a schnauzer dog

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    Mariana Isa Poci Palumbo

    2011-02-01

    Full Text Available Alterações adquiridas na coloração da pelagem de cães são raras. Schnauzers miniaturas podem apresentar desenvolvimento idiopático de coloração dourada do pelame, primariamente do tronco, chamada de aurotriquia. O presente trabalho relata a ocorrência de aurotriquia em um cão da raça schnauzer, de três anos de idade, sendo esse o primeiro relato de caso de aurotriquia em schnauzer no Brasil. Por se tratar de alteração de rara ocorrência, torna-se necessária maior atenção a características raciais e um melhor exame físico e anamnese, mesmo se tratando de alteração considerada meramente de fenótipo, pois existem as alterações de coloração bem piores, ligadas a doenças de prognóstico.Coat color changes in adult dogs are rare. Miniature schnauzers can development golden hair coat color, primarily in the trunk, called aurotriquia. This paper reports the occurrence of aurotriquia in a schnauzer, three years old, being this the first case report of aurotriquia schnauzer in Brazil. Due to its rare occurrence there is a need for greater attention to racial characteristics and a better physical examination and medical history, Despite, being only a change in the phenotype, there are color changes related to worse disease prognosis.

  11. Tipos especiales de niños

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    Mercedes Rodrigo Bellido

    1946-09-01

    Full Text Available En las tres últimas lecciones han sido expuestas algunas consideraciones referentes a niños y adolescentes desde el nacimiento hasta el dintel de la juventud. En todas ellas hemos procurado poner de relieve la necesidad de individualizar el conocimiento de cada niño para obtener mejores resultados en su adaptación a su futura vida de adultos, En todas ellas  nos hemos referido al llamado niño normal. Nos corresponde en la lección de hoy ocuparnos can la superficialidad característica de estas charlas tipo-muestrario, de otras categorías de niños muy dignos de interés.. quienes unas por exceso, otros por defecto, otros por dificultades de adaptación por diferentes causas, se desvían de la línea media de la normalidad. Consideramos que no está fuera del lugar, aquí, el tema de los niños excepcionales y por el contrario que es necesario intensificar el estudio de los trastornos de la vida mental y emocional de los niños en la preparación de los estudiantes de Medicina. Y no es nuestra solo esta opinión; no hace mucho tiempo en la Medical School de Ia Universidad de Minnessota hemos sabido que se ha hecho un intento de considerar y evaluar factores emocionales ambientales sobre las mismas bases que los descubrimientos fisiológicos.

  12. Doença cerebrovascular tipo "moyamoya"

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    Reynaldo A. Brandt

    1976-09-01

    Full Text Available É relatado o caso de um paciente masculino, branco, 34 anos, que apresentou hemorragia meníngea sem sinais de comprometimento cerebral. A carotidoangiografia direita mostrou as alterações típicas do "moyamoya", com estenose da artéria carótida interna ao nível do sifão, acima da origem da artéria comunicante posterior; há uma rede vascular angiomatosa anormal projetando-se na base do cérebro, da qual nascem as artérias cerebrais anterior e média, sendo as artérias comunicante e cerebral posterior hipertrofiadas e de trajeto tortuoso; há anastomoses meningo-corticiais, sendo as artérias meníngeas hipertrofiadas. A carotidoangiografia esquerda mostrou hipertrofia das artérias carótidas comum e interna, com contrastação de ambas as artérias cerebrais anteriores e médias a partir deste lado; a artéria comunicante anterior é do tipo fetal e há a presença anômala da artéria cerebral anterior mediana do corpo caloso. Estes dados apoiam a teoria segundo a qual a doença constitui anomalia do desenvolvimento vascular encefálico, não tendo sido encontrado outro caso na literatura com hipertrofia vicariante da artéria carótida interna contralateral à da lesão típica do "moyamoya".

  13. Herpes zoster sciatica mimicking lumbar canal stenosis: a case report.

    Science.gov (United States)

    Koda, Masao; Mannoji, Chikato; Oikawa, Makiko; Murakami, Masazumi; Okamoto, Yuzuru; Kon, Tamiyo; Okawa, Akihiko; Ikeda, Osamu; Yamazaki, Masashi; Furuya, Takeo

    2015-07-29

    Symptom of herpes zoster is sometimes difficult to distinguish from sciatica induced by spinal diseases, including lumbar disc herniation and spinal canal stenosis. Here we report a case of sciatica mimicking lumbar canal stenosis. A 74-year-old Chinese male patient visited our hospital for left-sided sciatic pain upon standing or walking for 5 min of approximately 1 month's duration. At the first visit to our hospital, there were no skin lesions. A magnetic resonance imaging showed spinal canal stenosis between the 4th and 5th lumbar spine. Thus, we diagnosed the patient with sciatica induced by spinal canal stenosis. We considered decompression surgery for the stenosis of 4th and 5th lumbar spine because conservative therapy failed to relieve the patient's symptom. At that time, the patient complained of a skin rash involving his left foot for several days. A vesicular rash and erythema were observed on the dorsal and plantar surfaces of the great toe and lateral malleolus. The patient was diagnosed with herpes zoster in the left 5th lumbar spinal nerve area based on clinical findings, including the characteristics of the pain and vesicular rash and erythema in the 5th lumbar spinal dermatome. The patient was treated with famciclovir (1,500 mg/day) and non-steroidal anti-inflammatory drugs. After 1 week of medication, the skin rash resolved and pain relief was obtained. In conclusion, spinal surgeons should keep in mind herpes zoster infection as one of the possible differential diagnoses of sciatica, even if there is no typical skin rash.

  14. Herpes encephalitis during pregnancy: a case report of maternal death

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    Leila Pourali

    2016-04-01

    Full Text Available Background: Herpes encephalitis is the most common cause of fatal encephalitis in the world which often presents with sudden fever, headache, seizure, focal neurologic symptoms, and consciousness loss. The aim of this study was to report a case of maternal death caused by herpes encephalitis which appropriate antibiotic therapy delayed because of early diagnosis of eclampsia. Case Presentation: A 16-year-old pregnant woman at 36th weeks of gestation was referred to gynecology emergency department of Ghaem Hospital, Mashhad University of Medical Sciences in 2016. She was admitted due to 4 times of generalized tonic-clonic seizures and blood pressure of 140/90 mmHg with diagnosis of eclampsia. Cesarean section was performed for fetal distress and eclampsia remote from delivery. 6 hours after cesarean section because of higher than 39 °C and reduction in consciousness status, she was transferred to intensive care unit (ICU. The first brain magnetic resonance imaging (MRI was normal. Lumbar puncture (LP was performed and brain MRI was repeated that increased signal was observed in two sides of basal ganglia. Intravenous acyclovir was administered by possible diagnosis of viral meningoencephalitis. Cerebrospinal fluid (CSF was positive in terms of herpes simplex virus type 1 (HSV-1. Unfortunately, the patient died 35 days after hospitalization by diagnosis of HSV-1 encephalitis and bilateral infarction with frequent seizures and clinical manifestation of septic shock refractory to treatment. Conclusion: Although the first diagnosis for generalized convulsion during pregnancy is eclampsia, but in case of recurrent and specially atypical seizures and low consciousness level, other diagnosis like meningoencephalitis, brain lesions and cavernous sinus thrombosis (CVT must be considered and ruled out.

  15. Genital Herpes: Insights into Sexually Transmitted Infectious Disease.

    Science.gov (United States)

    Jaishankar, Dinesh; Shukla, Deepak

    2016-06-27

    Etiology, transmission and protection: Herpes simplex virus-2 (HSV-2) is a leading cause of sexually transmitted infections with recurring manifestations throughout the lifetime of infected hosts. Currently no effective vaccines or prophylactics exist that provide complete protection or immunity from the virus, which is endemic throughout the world. Pathology/Symptomatology: Primary and recurrent infections result in lesions and inflammation around the genital area and the latter accounts for majority of genital herpes instances. Immunocompromised patients including neonates are susceptible to additional systemic infections including debilitating consequences of nervous system inflammation. Epidemiology, incidence and prevalence: More than 500 million people are infected worldwide and most reported cases involve the age groups between 16-40 years, which coincides with an increase in sexual activity among this age group. While these numbers are an estimate, the actual numbers may be underestimated as many people are asymptomatic or do not report the symptoms. Treatment and curability: Currently prescribed medications, mostly nucleoside analogs, only reduce the symptoms caused by an active infection, but do not eliminate the virus or reduce latency. Therefore, no cure exists against genital herpes and infected patients suffer from periodic recurrences of disease symptoms for their entire lives. Molecular mechanisms of infection: The last few decades have generated many new advances in our understanding of the mechanisms that drive HSV infection. The viral entry receptors such as nectin-1 and HVEM have been identified, cytoskeletal signaling and membrane structures such as filopodia have been directly implicated in viral entry, host motor proteins and their viral ligands have been shown to facilitate capsid transport and many host and HSV proteins have been identified that help with viral replication and pathogenesis. New understanding has emerged on the role of

  16. Genital Herpes: Insights into Sexually Transmitted Infectious Disease

    Science.gov (United States)

    Jaishankar, Dinesh; Shukla, Deepak

    2016-01-01

    Etiology, transmission and protection: Herpes simplex virus-2 (HSV-2) is a leading cause of sexually transmitted infections with recurring manifestations throughout the lifetime of infected hosts. Currently no effective vaccines or prophylactics exist that provide complete protection or immunity from the virus, which is endemic throughout the world. Pathology/Symptomatology: Primary and recurrent infections result in lesions and inflammation around the genital area and the latter accounts for majority of genital herpes instances. Immunocompromised patients including neonates are susceptible to additional systemic infections including debilitating consequences of nervous system inflammation. Epidemiology, incidence and prevalence: More than 500 million people are infected worldwide and most reported cases involve the age groups between 16-40 years, which coincides with an increase in sexual activity among this age group. While these numbers are an estimate, the actual numbers may be underestimated as many people are asymptomatic or do not report the symptoms. Treatment and curability: Currently prescribed medications, mostly nucleoside analogs, only reduce the symptoms caused by an active infection, but do not eliminate the virus or reduce latency. Therefore, no cure exists against genital herpes and infected patients suffer from periodic recurrences of disease symptoms for their entire lives. Molecular mechanisms of infection: The last few decades have generated many new advances in our understanding of the mechanisms that drive HSV infection. The viral entry receptors such as nectin-1 and HVEM have been identified, cytoskeletal signaling and membrane structures such as filopodia have been directly implicated in viral entry, host motor proteins and their viral ligands have been shown to facilitate capsid transport and many host and HSV proteins have been identified that help with viral replication and pathogenesis. New understanding has emerged on the role of

  17. DESCRIPTION OF ULTRASTRUCTURAL DAMAGES IN FROZEN-THAWED CANINE SPERMATOZOA DESCRIÇÃO DE DANOS ULTRAESTRUTURAIS EM ESPERMATOZOIDES CANINOS CONGELADOS-DESCONGELADOS

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    Viviane Helena Chirinéa

    2009-07-01

    Full Text Available In spite of the advances in transmission electronic microscopy (TEM, there are few studies presenting a systematic description of the canine spermatozoa and they are only focused on sperm cell heads. The goal of the present study was to describe ultrastructural appearance of canine fresh and frozen-thawed spermatozoa, focusing on damages induced by freezing-thawing in different sperm regions. Ten ejaculates from five proven stud dogs (two ejaculates/dog were collected, evaluated, extended in Tris-egg yolk-glycerol, frozen and stored in liquid nitrogen, and thawed six weeks later.  Samples were evaluated for progressive motility, morphology, and for ultrastructural analysis by TEM. Concerning to TEM, the most striking differences between fresh and frozen-thawed samples were observed over the mid-piece since the fresh spermatozoa showed a well preserved mid-piece. However, the frozen-thawed spermatozoa mid-piece showed signs of damage such as mitochondrial vacuolization. In conclusion, freezing-thawing processes using a Tris-egg yolk extender induce ultrastructural damages in head and mid-piece of canine sperm, affecting the mitochondrial ultrastructure besides.

    KEY WORDS: Cryopreservation, dog, semen, ultrastructure.
    Apesar dos avanços na microscopia eletrônica de transmissão (MET, existem poucos estudos apresentando uma descrição sistemática do espermatozoide canino, os quais estão focados apenas na cabeça espermática. Objetivou-se, com o presente estudo, descrever a aparência ultraestrutural do espermatozoide canino fresco e congelado-descongelado, enfocando os danos induzidos pela congelação e descongelação em diferentes regiões espermáticas. Dez ejaculados obtidos de cinco cães (dois ejaculados por cão foram coletados, avaliados e diluídos em Tris-gema-glicerol, congelados e armazenados em nitrogênio líquido, e descongelados seis semanas após. Avaliaram-se as amostras quanto à motilidade progressiva

  18. Soroprevalência de anticorpos contra vírus herpes simples 1-2 no Brasil Seroprevalencia de anticuerpos contra virus herpes simples 1-2 en Brasil Seroprevalence of herpes simplex 1-2 antibodies in Brazil

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    Sue Ann Costa Clemens

    2010-08-01

    Full Text Available OBJETIVO: Estimar a soroprevalência de anticorpos por vírus herpes simples (HSV-1 e HSV-2 e analisar fatores associados no Brasil. MÉTODOS: Estudo transversal realizado entre 1996 e 1997 em 1.090 indivíduos com idade entre um e 40 anos da população geral, em quatro diferentes regiões geográficas no Brasil. Foram analisadas amostras sangüíneas para detecção de anticorpos para HSV-1 e HSV-2 com teste tipo-específico Elisa. Foram descritas freqüências e proporções, comparadas entre grupos utilizando o teste de Fisher bilateral exato. Foi realizada análise de regressão logística para avaliar influência das variáveis sociodemográficas e histórico de DST, sobre a soroprevalência de HSV-1 e/ou HSV-2. RESULTADOS: As soroprevalências de anticorpos para HSV-1 e HSV-2, ajustadas por idade, foram 67,2% e 11,3% respectivamente, sem diferença quanto ao sexo e maiores na Região Norte. As soroprevalências aumentaram com a idade, e para HSV-2 o maior aumento ocorreu na adolescência e entre adultos jovens. Indivíduos soropositivos para HSV-1 apresentaram maior risco de serem positivos para HSV-2 (15,7% quando comparados com os negativos para HSV-1 (4,7%. Na análise multivariada, o histórico de DST aumentou significativamente (OR=3,2 a probabilidade de soropositividade para HSV-2. CONCLUSÕES: As soroprevalências para HSV-1 e para HSV-2 variam com a idade e entre as regiões do Brasil. História pregressa de DST é importante fator de risco para aquisição de infecção por HSV-2.OBJETIVO: Estimar la seroprevalencia de anticuerpos por virus herpes simples (HSV-1 y HSV-2 en diferentes áreas geográficas en Brasil y analizar factores asociados. MÉTODOS: Estudio transversal realizado entre 1996 y 1997 con individuos de la población en general en cuatro diferentes áreas geográficas en Brasil y estratificados por edad (de uno a 40 años y sexo, de los cuales 1.090 fueron incluidos en el análisis final. Fueron analizadas muestras

  19. Orbital apex syndrome secondary to herpes zoster virus infection

    Science.gov (United States)

    Merino-Iglesias, Alexia; Montero, Javier Antonio; Calabuig-Goena, Maria; Giraldo-Agudelo, Luisa Fernanda

    2014-01-01

    A male patient with herpes zoster ophthalmicus (HZO) presented with left exophthalmos, external and internal ophthalmoplegia and decreased visual acuity. A CT scan revealed myositis without significant compression of the optic nerve. Intravenous acyclovir and oral steroids were started with improvement of the symptoms and eventual complete recovery.Orbital apex syndrome is a rare complication of HZO. Multiple pathogenic mechanisms are involved, including a direct cytopathic effect of the virus as in the present case. Early diagnosis and therapy may lead to complete recovery of visual function. PMID:24614776

  20. Herpes zoster at two different sites in the same individual

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    Kolalapudi Seetharam

    1995-01-01

    Full Text Available Herpes zoster occuring at two different sites in the same individual at the same time, involving more than two segments at each site has rarely been reported. We recently observed two such cases. The first patient was HIV-infected 10 year old haemophiliac who had zoster involving the distribution of the right C4, 5, 6 and left L 2, 3, 4 dermatomes and the second one was a 50 year old renal transplant recipient on immunosuppressive drugs who developed zoster at left C3, 4, 5 and left T 7, 8, 9.

  1. Prevention strategies for herpes zoster and post-herpetic neuralgia

    Science.gov (United States)

    Levin, Myron J.; Gershon, Anne A.; Dworkin, Robert H.; Brisson, Marc; Stanberry, Lawrence

    2017-01-01

    SUMMARY Impairment of varicella zoster virus (VZV)-specific cell-mediated immunity, including impairment due to immunosenescence, is associated with an increased risk of developing herpes zoster (HZ), whereas levels of anti-VZV antibodies do not correlate with HZ risk. This crucial role of VZV-specific cell-mediated immunity suggests that boosting these responses by vaccination will be an effective strategy for reducing the burden of HZ. Other strategies focus on preventing the major complication of HZ – post-herpetic neuralgia. These strategies include pre-emptive treatment with drugs such as tricyclic antidepressants, anticonvulsants and analgesics. PMID:20510262

  2. A Herpes Simplex Virus Infection Secondary to Acupuncture and Cupping

    Science.gov (United States)

    Jung, Ye-Jin; Kim, Jae-Hong; Lee, Hae-Jin; Bak, Hana; Hong, Seung Phil; Jeon, Soo Young

    2011-01-01

    Acupuncture and cupping have a public reputation as being safe even though these practices can lead to complications such as trauma or infection. We report here on a case of herpes simplex virus (HSV) infection secondary to acupuncture and cupping in a 56-year-old woman. The patient, who had a history of acupuncture and cupping on her left forearm for treating her myalgia, developed painful papules. Histologically, the biopsy specimen showed characteristic ballooning degeneration and inclusion bodies in the epidermis and mid-dermis. These clinical and histological findings were consistent with the diagnosis of HSV infection. PMID:21738366

  3. Unilateral Negative Myoclonus Caused by Herpes Simplex Virus Encephalitis

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    Jin-Mo Park

    2011-05-01

    Full Text Available Various neurologic manifestations of herpes simplex virus (HSV encephalitis have been reported on the literatures. Chorea, ballism, choreoathetosis and myoclonus were reported as movement disorders which might be related with brain lesion by HSV encephalitis, but negative myoclonus (NM has never been reported before. NM can be characterized as a shock-like involuntary jerky movement caused by a sudden, brief interruption of muscle activity. We experienced a case of HSV encephalitis with NM in unilateral arm and leg. In polygraphic monitoring, electroencephalography (EMG silent periods are 50–250 ms in duration with no detectable EMG correlate.

  4. Herpes zoster infection: Report of a treated case

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    Kotya Naik Maloth

    2015-01-01

    Full Text Available Herpes zoster (HZ is an acute infectious viral disease result from reactivation of the DNA varicella-zoster virus, which occurs more frequently among older adults and immunocompromised persons. The most common complication of HZ is postherpetic neuralgia, a chronic often debilitating pain condition that can last months or even years. Deaths attributable to zoster are common among immunocompromised persons. Prompt treatment with the antiviral drugs, corticosteroids and analgesics decrease the severity and duration of acute pain from HZ. Here, we report a treated case of HZ in 35-year-old male involving all three branches of the trigeminal nerve without any complication.

  5. Topical therapy of recurrent herpes - acyclovir versus tromantidine

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    Kumar Bhushan

    1991-01-01

    Full Text Available Fifty men with recurrent genital herpes were treated with either acyclovir 5% cream or tromantidine 1 % ointment applied topically. Acyclovir cream was applied 5 times and tromantidine cream 4 times daily for 5 days. At least one pre-treatment episode was observed by one of the authors. Self assessment charts were provided to the patients to record prodromal symptoms and healing time. For comparison at least 3 post treatment episodes were observed and com-pared with mean healing time of 3 pre-treatment episodes. Both acyclovir cream and tromantidine ointment significantly reduced the duration of prodrome, hastened healing and so reduced mean healing time.

  6. Computed tomography (CT) in children with herpes simplex encephalitis

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    Taccone, A.; Gambaro, G.; Ghiorzi, M.; Fondelli, P.; Ferrea, G.; Gianbartolomei, G.; Rolando, S.

    1988-11-01

    Computed Tomography (CT) scans were obtained from nine infants with herpes simplex virus encephalitis (HSE). The early CT findings were generalized or localized edematous change and a mass effect was also seen in two cases. In the follow-up study two patients showed bilateral gyriform calcification, a rare occurrence in association with intracranial infection. The appearance of multicystic encephalomalacia was evident in one patient 3 months after the onset of disease. It is shown that the CT findings of neonates and young children with HSE are different from those of adults.

  7. Computed tomography (CT) in children with herpes simplex encephalitis.

    Science.gov (United States)

    Taccone, A; Gambaro, G; Ghiorzi, M; Ferrea, G; Gianbartolomei, G; Rolando, S; Fondelli, P

    1988-01-01

    Computed Tomography (CT) scans were obtained from nine infants with herpes simplex virus encephalitis (HSE). The early CT findings were generalized or localized edematous change and a mass effect was also seen in two cases. In the follow-up study two patients showed bilateral gyriform calcification, a rare occurrence in association with intracranial infection. The appearance of multicystic encephalomalacia was evident in one patient 3 months after the onset of disease. It is shown that the CT findings of neonates and young children with HSE are different from those of adults.

  8. Herpes simplex infection in a juvenile orangutan (Pongo pygmaeus pygmaeus).

    Science.gov (United States)

    Kik, Maria J L; Bos, Jan H; Groen, Jan; Dorrestein, Gerry M

    2005-03-01

    A juvenile orangutan (Pongo pygmaeus pygmaeus) died after 8 days of diarrhea and vomiting. Necropsy showed petechial hemorrhages in the skin, the myocardium, and the peritoneal membranes. The lungs were hyperemic and edematous, and the liver and spleen were enlarged. Histologic changes consisted of interstitial pneumonia, hepatitis, and splenic hyperplasia. Numerous eosinophilic intranuclear inclusion bodies were visible in pulmonary epithelial cells, hepatocytes, and splenic endothelial cells. Electron microscopic examination revealed herpesvirus in hepatocyte nuclei. Polymerase chain reaction of liver tissue demonstrated the presence of a herpes simplex virus-1.

  9. No association between herpes simplex virus 1 and cardiac myxoma

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    Schurr, U.; Berdajs, D A; Bode, B.; Dzemali, O.; Emmert, M. Y.; Genoni, M

    2011-01-01

    PRINCIPLES: Cardiac myxoma is the most commonly diagnosed cardiac tumour. Infection of herpes simplex virus 1 (HSV1) has been postulated to be a factor for this pathologic entity. The aim of the current study was to evaluate the association between HSV 1 and myxoma occurrence.METHODS: Between 1965 and 2005, 70 patients (36 female, mean age: 52.6 years) underwent a resection of myxoma. Selected variables such as hospital mortality and morbidity were studied. A follow-up (FU; mean FU time: 138 ...

  10. [Rare forms of segmental exanthema in patients with Herpes zoster].

    Science.gov (United States)

    Shishov, A S; Blank, I A; Petrova, I S; Kulagina, M V; Rusanova, S A

    2014-01-01

    To describe rare clinical cases of Herpes zoster with a rash appeared simultaneously in different segmental zones (zoster duplex unilateralis and zoster duplex bilateralis). Brief details of medical histories of 3 patients are presented. A very rare possibility of the complete fusion of bilateral exanthema on the same topographic level with the development of an entire zoster that confirm a historical name of the disease has been demonstrated. A mistaken translation of disease name into Russian as "lishai" is emphasized. Recommendations on the complex, stage-by-stage treatment of patients, including psychotherapeutic treatment of the pain syndrome, are presented.

  11. TORSIÓN LOBAR PULMONAR ESPONTÁNEA EN UN CANINO MESTIZO Y POSTERIOR DESARROLLO DE UNA NEOPLASIA ÓSEA APENDICULAR: REPORTE DE CASO

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    J.L. Granados

    2013-01-01

    Full Text Available Se describe el caso de un canino mestizo hembra de ocho años de edad que presentó historia de diez días de letargia, anorexia, pérdida de peso, vómito ocasional, tos esporádica y dificultad respiratoria; los hallazgos clínicos, radiográficos y ultrasonográficos sugirieron como diagnóstico diferencial más probable torsión lobar pulmonar del lóbulo medio derecho, lo cual se confirmó mediante toracotomía exploratoria. el manejo terapéutico incluyó resección del lóbulo afectado; no se identificó ninguna etiología subyacente. La paciente tuvo una recuperación completa de la torsión lobar; sin embargo, dos se-manas después de la cirugía presentó claudicación severa del miembro anterior derecho y se encontraron hallazgos radiográficos compatibles con neoplasia ósea en la epífisis proximal del húmero. Por decisión de los propietarios sólo se realizó manejo analgésico y un mes después se practicó eutanasia debido a una posible metástasis pulmonar. es posible que la neoplasia y posible metástasis se tratasen de eventos concomitantes sin relación causa-efecto; sin embargo, pudo haber existido una asociación entre un proceso estresante y traumático (la torsión pulmonar con el desarrollo y manifestación de una patología oncológica subyacente.

  12. ESTANDARIZACIÓN DE LA PRUEBA PARA ESPECTROFOTOMETRÍA EN LA MEDICIÓN DE CONCENTRACIÓN DE SEMEN BOVINO, EQUINO, PORCINO, OVINO Y CANINO

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    Rodríguez P

    2008-01-01

    Full Text Available el objetivo de este trabajo fue comparar dos métodos para la medición de concentración espermática, espectrofotometría y cámara de neubauer, para las especies bovina, equina, porcina, ovina y canina, verificando el porcentaje de correlación existente entre las pruebas y generando así un índice que permitiera la lectura equivalente en ambos métodos.se evaluaron 20 eyaculados por especie, de distintos machos escogidos al azar. Cada una de las muestras fue diluida a 1:100 en citrato de sodio al 2,9%, y procesadas tanto en la cámara de neubauer como en el espectrofotómetro. arrojando valores equivalentes por densidad y conteo celular con una alta correlación (r = 0,97; 0,97; 0,96; 0,92; 0,99, en bovinos, equi-nos, porcinos, ovinos y caninos, respectivamente. de esta manera, se generó una tabla por especie para la determinación del número real de espermatozoides en la muestra medida por espectrofotometría. Los resultados del presente estudio demuestran que la medición de concentración espermática por medio de espectrofotometría es un método rápido y preciso que permite la agilización en el proceso de evaluación reproductiva del macho en diferentes especies.

  13. Estudio retrospectivo de masas cutáneas neoplásicas en caninos diagnosticadas histopatológicamente en la Universidad de La Salle (1999-2003

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    Carlos Eduardo Aparicio Ortiz

    2008-12-01

    Full Text Available El propósito del trabajo fue realizar un análisis retrospectivo de las neoplasias cutáneas en caninos diagnosticadas en la Universidad de La Salle, en Bogotá, en el período 1999-2003. El presente estudio se llevó a cabo con la información obtenida de los registros del área diagnóstica e histopatológica de la Universidad de La Salle. La información fue discriminada y analizada teniendo en cuenta las siguientes variables: diagnóstico, raza, sexo, edad, malignidad y localización del tumor. Los 192 casos de pacientes abordados en el estudio fueron agrupados de acuerdo con las neoplasias con el fin de determinar las características y el comportamiento de dichas patologías. La edad promedio de los pacientes fue de 6,5 años, la raza más afectada el Bóxer con el 19,1% (32 perros, seguido del Labrador con un 13% (26 perros y el Caniche con un 10,5% (22 perros; los pacientes machos fueron los más afectados con un 58% (107 perros. Se reveló la gran incidencia del tumor de células de mast (26,2% en el 2003 y 20% en el 2002 y el histiocitoma (12,3% en el 2003 y 10% en el año 2002. Entre otras neoplasias que se observaron de forma recurrente en el estudio se destacan el lipoma, tricoepitelioma, carcinoma de células escamosas y papilomatosis.

  14. Environmental risk factors related to the development of canine non-Hodgkin's lymphoma Fatores de risco ambientais relacionados ao desenvolvimento do linfoma não Hodgkin canino

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    Danielle Almeida Zanini

    2013-01-01

    Full Text Available This research aimed to investigate the possible risk factors associated with the development of canine non-Hodgkin's lymphoma. Owners of 83 dogs with non-Hodgkin's lymphoma and of 84 healthy dogs answered an epidemiological questionnaire. Dogs who lived outside of the house and within 100 meters of busy streets or avenues (defined as more than 50 vehicles per minute had a higher risk for developing the disease (OR: 3.1, 95% CI: 1.4-6.9, P=0.005. These results suggest that air pollution derived from vehicle traffic may be associated with the development of canine non-Hodgkin's lymphoma.Este trabalho teve como objetivo investigar os possíveis fatores de risco ambientais, associados com o desenvolvimento de linfoma não-Hodgkin nos cães. Um questionário epidemiológico foi aplicado aos proprietários de 83 cães com linfoma não-Hodgkin e 84 proprietários de cães saudáveis. Os cães que viviam permanentemente no lado de fora da casa e em torno de 100 metros de ruas movimentadas ou avenidas (mais de 50 veículos por minuto tiveram um maior risco de desenvolvimento da doença (OR: 3,1, IC 95%: 1,4-6,9, P=0,005. Esses resultados sugerem que a poluição do ar oriunda do tráfego veicular pode estar associada com o desenvolvimento de linfomas não-Hodgkin canino.

  15. A systematic review and meta-analysis on herpes zoster and the risk of cardiac and cerebrovascular events.

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    Nathaniel Erskine

    Full Text Available Patients who develop herpes zoster or herpes zoster ophthalmicus may be at risk for cerebrovascular and cardiac complications. We systematically reviewed the published literature to determine the association between herpes zoster and its subtypes with the occurrence of cerebrovascular and cardiac events.Systematic searches of PubMed (MEDLINE, SCOPUS (Embase and Google Scholar were performed in December 2016. Eligible studies were cohort, case-control, and self-controlled case-series examining the association between herpes zoster or subtypes of herpes zoster with the occurrence of cerebrovascular and cardiac events including stroke, transient ischemic attack, coronary heart disease, and myocardial infarction. Data on the occurrence of the examined events were abstracted. Odds ratios and their accompanying confidence intervals were estimated using random and fixed effects models with statistical heterogeneity estimated with the I2 statistic. Twelve studies examining 7.9 million patients up to 28 years after the onset of herpes zoster met our pre-defined eligibility criteria. Random and fixed effects meta-analyses showed that herpes zoster, type unspecified, and herpes zoster ophthalmicus were associated with a significantly increased risk of cerebrovascular events, without any evidence of statistical heterogeneity. Our meta-analysis also found a significantly increased risk of cardiac events associated with herpes zoster, type unspecified.Our results are consistent with the accumulating body of evidence that herpes zoster and herpes zoster ophthalmicus are significantly associated with cerebrovascular and cardiovascular events.

  16. Tipos de interés de los productos bancarios

    OpenAIRE

    Gonzalo Aguado, David

    2016-01-01

    EI trabajo analiza los tipos de interes que las entidades financieras establecen en sus productos. Se configura en tres bloques: Operaciones de Activo, Operaciones de Pasivo y Otras Operaciones. Se puede comprobar que tienen dos opciones : Aplicar un tipo de interés fijo, con el que desde el primer momento conocemos la totalidad de lo que vamos a pagar. La otra opción es aplicar un tipo de interés variable, normalmente aplicando el Euribor más una parte fija. Dentro de cada producto bancario,...

  17. Nuevo tipo de apoyos y articulaciones

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    Andrä, Fritz Leonhardt

    1963-11-01

    of theoretical and technical difficulties inherent in these bearings: they also express acknowledgement to German individuals and institutions, for their contribution to this investigation.Las tendencias actuales son funciones que dependen directamente de la presencia creciente y mejorada de los materiales de construcción que se ofrecen al comercio. En el campo de los materiales cabe una marcada subdivisión en naturales y preparados o sintéticos; estos últimos constituyen la preocupación de los autores para su aprovechamiento y adecuada aplicación. De entre ellos, las resinas sintéticas o caucho artificial, dentro de las distintas especies de la extensa familia han gozado de un lugar preferente en este estudio de nuevos tipos de apoyos que presentan los notables ingenieros alemanes Wolfhart Andrä y Fritz Leonhardt. En los ensayos de laboratorio y a escala natural, las variedades comerciales de estas resinas, conocidas con los nombres de «neopreno» y «Teflon», han sido elegidas por presentar, por lo menos actualmente, características marcadamente apropiadas a la finalidad perseguida en este estudio, del que se confía ulterior desarrollo y mejor acogida, por las importantes aplicaciones que de él se derivan en el campo de la ingeniería y construcción. Los autores estudian con detenimiento y sobrado rigor para las aplicaciones prácticas las deformaciones que de estos materiales se espera al someterlos a fuerzas de gran concentración. En los apoyos juega particular interés la distribución de la carga siempre concentrada en superficies relativamente pequeñas, lo que exige elevadas cargas unitarias y, con ello, la utilización de materiales extremadamente nobles para resistirlas con la resistencia que las deformaciones instantáneas requieren para recobrar rápidamente la posición de estabilidad perdida momentáneamente. La fatiga en el ciclo de deformaciones relaja los materiales, y ha de tenerse presente al considerar las características que los

  18. Mucopolissacaridose tipo VI: relato de caso

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    Lais Orosco Bialon Santana

    2014-10-01

    Full Text Available Introdução: As mucopolissacaridoses são erros inatos do metabolismo de depósito lisossomal subclassificadas segundo a enzima deficiente. A arilsulfatase B (ARSB, responsável por degradar os glicosaminoglicanos (GAGs, que atuam no tecido conjuntivo, é deficiente na mucopolissacaridose tipo VI (MP VI. A MP VI tem clínica variável, sem anormalidades ao nascimento, evidenciando-se progressivamente ao acúmulo de GAGs. O diagnóstico se faz pela redução da atividade da ARSB ou da mutação genética. A principal causa de óbito é insuficiência cardíaca, ocorrendo na segunda ou terceira década de vida. Relato de Caso: Masculino, 4 anos, portador de MP VI, há 3 dias com febre e sinais flogísticos em sítio de acesso central, colocado para reposição enzimática, com flutuação e saída de material purulento. Ultrassom evidenciou coleção laminar e borramento de planos gordurosos. Ecocardiograma demonstra hipertensão pulmonar discreta decorrente de prolapso valvar mitral com refluxo discreto, além de endocardite da valva mitral. Optou-se por retirada cirúrgica do dispositivo e administração de vancomicina e amicacina. Durante internação, evoluiu bem, sem complicações pós operatórias. Conclusão: A MP VI têm inteligência preservada, baixa estatura e alterações osteomusculares, como no caso relatado. Não há correlação entre a gravidade clínica e a atividade residual enzimática. Dificuldade respiratória pode levar a hipóxia crônica, hipertensão pulmonar e insuficiência cardíaca congestiva. Das alterações cardíacas, encontramos valvulopatias, insuficiência cardíaca e hipertensão pulmonar, observadas no caso. O tratamento se faz com transplante de células-tronco hematopoiéticas e terapia de reposição enzimática.

  19. Genital herpes in children under 11 years and investigations for sexual abuse.

    Science.gov (United States)

    Reading, Richard; Hughes, Gwenda; Hill, Julia; Debelle, Geoff

    2011-08-01

    The implications for sexual abuse investigation of genital herpes in a child are uncertain because of a lack of good quality research evidence. The incidence, presenting features, history of exposure, indicators of child maltreatment and outcomes of child protection investigations in children with genital herpes are described. Ascertainment of all cases of genital herpes in children herpes simplex type 1, eight were tested for other sexually transmitted infections (STIs), and only one had a full STI screen. Three cases had other clinical features suggestive of sexual abuse. Six cases were referred for child protection investigation, but no sexual abuse was substantiated. Genital herpes in children under 11 years is rare. Almost a third of children diagnosed with genital herpes did not have appropriate virological investigation and few were screened for other STIs. Around a quarter of cases were referred to child protection agencies for further investigation, which limits any inferences in this study about mode of transmission in children. Sexual abuse guidance should emphasise the need for thorough assessment and investigation in cases of genital herpes in children.

  20. Isolation of herpes simplex virus from the genital tract during symptomatic recurrence on the buttocks.

    Science.gov (United States)

    Kerkering, Katrina; Gardella, Carolyn; Selke, Stacy; Krantz, Elizabeth; Corey, Lawrence; Wald, Anna

    2006-10-01

    To estimate the frequency of isolation of herpes simplex virus (HSV) from the genital tract when recurrent herpes lesions were present on the buttocks. Data were extracted from a prospectively observed cohort attending a research clinic for genital herpes infections between 1975 and 2001. All patients with a documented herpes lesion on the buttocks, upper thigh or gluteal cleft ("buttock recurrence") and concomitant viral cultures from genital sites including the perianal region were eligible. We reviewed records of 237 subjects, 151 women and 86 men, with a total of 572 buttock recurrences. Of the 1,592 days with genital culture information during a buttock recurrence, participants had concurrent genital lesions on 311 (20%, 95% confidence interval [CI] 14-27%) of these days. Overall, HSV was isolated from the genital region on 12% (95% CI 8-17%) of days during a buttock recurrence. In the absence of genital lesions, HSV was isolated from the genital area on 7% (95% CI 4%-11%) of days during a buttock recurrence and, among women, from the vulvar or cervical sites on 1% of days. Viral shedding of herpes simplex virus from the genital area is a relatively common occurrence during a buttock recurrence of genital herpes, even without concurrent genital lesions, reflecting perhaps reactivation from concomitant regions of the sacral neural ganglia. Patients with buttock herpes recurrences should be instructed about the risk of genital shedding during such recurrences. II-2.

  1. Hospitalizations realted to herpes zoster infection in the Canary Islands, Spain (2005-2014).

    Science.gov (United States)

    García-Rojas, Amós; Gil-Prieto, Ruth; Núñez-Gallo, Domingo Ángel; Matute-Cruz, Petra; Gil-de-Miguel, Angel

    2017-08-24

    Herpes zoster is an important problem of public health especially among the elderly in Spain. A population-based retrospective epidemiological study to estimate the burden of herpes zoster requiring hospitalization in the Canary Islands, Spain was conducted by using data from the national surveillance system for hospital data, Conjunto Mínimo Básico de Datos. Records of all patients admitted to hospital with a diagnosis of herpes zoster in any position and cases of primary diagnosis (ICD-9-MC codes 053.0-053.9) during a 10-year period (2005-2014), were selected. A total of 1088 hospitalizations with a primary or secondary diagnosis of herpes zoster were identified during the study period. Annually there were 6.99 hospitalizations by herpes zoster per 100,000 population. It increases with age reaching a maximum in persons ≥85 years of age (43.98 admissions per 100,000). Average length of hospitalization was 16 days and 73 patients died, with a case-fatality rate of 4.03%. In 22% of the cases hospitalized, herpes zoster was the primary diagnosis. The hospitalization burden of herpes zoster in adults in the Canary Islands was still important during the last decade and justify the implementation of preventive measures, like vaccination in the elderly or other high risk groups to reduce the most severe cases of the disease.

  2. Herpes viruses and periodontopathic bacteria in early-onset periodontitis.

    Science.gov (United States)

    Kamma, J J; Contreras, A; Slots, J

    2001-09-01

    This study examined the occurrence of human herpes viruses and suspected periodontopathic bacteria in early-onset periodontitis patients who experienced progressive disease in at least 2 periodontal sites during the maintenance phase of therapy. In each of 16 individuals (9 male and 7 female; mean age 33.1+/-2.6 years), subgingival plaque samples were collected from 2 deteriorating and 2 stable periodontitis sites. A nested polymerase chain reaction method determined the presence of human cytomegalovirus (HCMV), Epstein-Barr virus type 1 (EBV-1) and herpes simplex virus (HSV). A 16s rRNA polymerase chain reaction method identified Porphyromonas gingivalis, Dialister pneumosintes, Bacteroides forsythus and Actinobacillus actinomycetemcomitans. HCMV was detected in 59.4% of active and in 12.5% of stable sites (pperiodontitis sites showing herpesvirus co-infection and all but one site showing P. gingivalis and D. pneumosintes co-infection revealed bleeding upon probing. HCMV, EBV-1, HSV and herpesvirus co-infection, as well as P. gingivalis, D. pneumosintes and P. gingivalis-D. pneumosintes co-infection were statistically associated with active periodontitis. Herpesviruses are immunosuppressive and may set the stage for overgrowth of subgingival P. gingivalis, D. pneumosintes and other periodontopathic bacteria. Understanding the significance of herpesviruses in human periodontitis may allow for improved diagnosis, more specific therapy and, ultimately, disease prevention.

  3. Herpes Simplex Esophagitis in Immunocompetent Host: A Case Report

    Directory of Open Access Journals (Sweden)

    G. Geraci

    2009-01-01

    Full Text Available Introduction. Herpes simplex esophagitis is well recognized in immunosuppressed subjects, but it is infrequent in immunocompetent patients. We present a case of HSE in a 53-year-old healthy man. Materials and Methods. The patient was admitted with dysphagia, odynophagia, and retrosternal chest pain. An esophagogastroduodenoscopy revealed minute erosive area in distal esophagus and biopsies confirmed esophagitis and findings characteristic of Herpes Simplex Virus infection. Results. The patients was treated with high dose of protonpump inhibitor, sucralfate, and acyclovir, orally, with rapid resolution of symptoms. Discussion. HSV type I is the second most common cause of infectious esophagitis. The majority of symptomatic immunocompetent patients with HSE will present with an acute onset of esophagitis. Endoscopic biopsies from the ulcer edges should be obtained for both histopathology and viral culture. In immunocompetent host, HSE is generally a self-limited condition. Conclusions. HSE should be suspected in case of esophagitis without evident cause, even if the patient is immunocompetent. When the diagnosis of HSE is confirmed, careful history and assessment for an immune disorder such as HIV infection is crucial, to look for underlying immune deficiency.

  4. PAPILLEDEMA: AN UNUSUAL FINDING IN A PATIENT WITH HERPES ENCEPHALITIS

    Directory of Open Access Journals (Sweden)

    A. Sudbakhsh

    2007-08-01

    Full Text Available Herpes simplex virus accounts for 10 to 25% of sporadic viral encephalitis throughout the world among people of different age with two peaks, one at 5 to 30 and the other at > 50 years of age. Pathologic process includes focal brain tissue inflammation and necrosis (predominantly temporal lobe. Therefore local neurological signs and symptoms will ensue. Although CSF pressure rising due to inflammation is expected, papilledema which is defined as a noninflammatory congestion of optic disk due to raised intracranial pressure has not yet been mentioned as a sign of focal encephalitis. In this article we report a 24 year-old patient with headache, fever and some degree of cognitive disorder who was definitely diagnosed (with MRI and PCR technique and treated for herpes encephalitis. Unexpectedly he had papilledema which led to more investigation. Most signs and symptoms disappeared during two weeks of intravenous acyclovir therapy as did papilledema to some extent. In this case, positive CSF PCR test for HSV confirmed the diagnosis. However it seems that along with starting acyclovir therapy, performing other supplementary studies (e.g. CT scan, MRI with and without I.V. contrast, CSF cytology and serologic tests for HIV to rule out other conditions that may be associated with papilledema and focal neurological signs (like malignancies, is mandatory.

  5. The molecular basis of herpes simplex virus latency

    Science.gov (United States)

    Nicoll, Michael P; Proença, João T; Efstathiou, Stacey

    2012-01-01

    Herpes simplex virus type 1 is a neurotropic herpesvirus that establishes latency within sensory neurones. Following primary infection, the virus replicates productively within mucosal epithelial cells and enters sensory neurones via nerve termini. The virus is then transported to neuronal cell bodies where latency can be established. Periodically, the virus can reactivate to resume its normal lytic cycle gene expression programme and result in the generation of new virus progeny that are transported axonally back to the periphery. The ability to establish lifelong latency within the host and to periodically reactivate to facilitate dissemination is central to the survival strategy of this virus. Although incompletely understood, this review will focus on the mechanisms involved in the regulation of latency that centre on the functions of the virus-encoded latency-associated transcripts (LATs), epigenetic regulation of the latent virus genome and the molecular events that precipitate reactivation. This review considers current knowledge and hypotheses relating to the mechanisms involved in the establishment, maintenance and reactivation herpes simplex virus latency. PMID:22150699

  6. Unusual Initial Presentation of Herpes Simplex Virus as Inguinal Lymphadenopathy

    Directory of Open Access Journals (Sweden)

    Sarah A. Fleming

    2015-01-01

    Full Text Available Genital herpes simplex virus (HSV infections are a common cause of inguinal lymphadenopathy. However, surgical excision of enlarged inguinal nodes is almost never performed to initially diagnose genital herpes simplex virus, due to the distinct external presentation of genital herpetic vesicles that usually occur with the first symptoms of infection. Therefore, the histologic and immunophenotypic features of HSV-associated inguinal lymphadenopathy are unfamiliar to most pathologists. The current report describes the lymph node pathology of two immunocompetent patients, whose initial HSV diagnosis was established through surgical excision of enlarged inguinal lymph nodes. Histologic examination showed features consistent with viral lymphadenopathy, including florid follicular hyperplasia, monocytoid B-cell hyperplasia, and paracortical hyperplasia without extensive necrosis. Immunohistochemical stains for HSV antigens, using polyclonal anti-HSV I and II antibodies, demonstrate strong immunoreactivity for HSV in a small number of cells in the subcapsular sinuses, especially in areas with monocytoid B-cell hyperplasia. Rare scattered HSV-positive cells also are identified in paracortical areas and germinal centers. We conclude that an initial diagnosis of genital HSV infection may be established by inguinal lymph node biopsy.

  7. Exploiting Herpes Simplex Virus Entry for Novel Therapeutics

    Directory of Open Access Journals (Sweden)

    Deepak Shukla

    2013-06-01

    Full Text Available Herpes Simplex virus (HSV is associated with a variety of diseases such as genital herpes and numerous ocular diseases. At the global level, high prevalence of individuals who are seropositive for HSV, combined with its inconspicuous infection, remains a cause for major concern. At the molecular level, HSV entry into a host cell involves multiple steps, primarily the interaction of viral glycoproteins with various cell surface receptors, many of which have alternate substitutes. The molecular complexity of the virus to enter a cell is also enhanced by the existence of different modes of viral entry. The availability of many entry receptors, along with a variety of entry mechanisms, has resulted in a virus that is capable of infecting virtually all cell types. While HSV uses a wide repertoire of viral and host factors in establishing infection, current therapeutics aimed against the virus are not as diversified. In this particular review, we will focus on the initial entry of the virus into the cell, while highlighting potential novel therapeutics that can control this process. Virus entry is a decisive step and effective therapeutics can translate to less virus replication, reduced cell death, and detrimental symptoms.

  8. Caninos permanentes retidos por palatino: diagnóstico e terapêutica: uma sugestão técnica de tratamento Palatine impacted permanent maxillary canines: diagnose and therapeutics

    Directory of Open Access Journals (Sweden)

    Mario Cappellette

    2008-02-01

    Full Text Available Os dentes seguem uma seqüência de erupção favorável no desenvolvimento da oclusão normal, mas algum distúrbio desse mecanismo, nesse período de transição da dentadura mista para a permanente, pode levar a alterações na seqüência ou mesmo no trajeto de erupção, levando a impactação de dentes. Os caninos superiores permanentes, depois dos terceiros molares, apresentam maior ocorrência de impactação, especialmente na região palatina, mesmo na presença de espaço suficiente para o seu alinhamento na arcada dentária. Na impossibilidade do diagnóstico precoce, esforços serão empregados para reposicionar o dente no arco dentário evitando sua extração, dada a sua importância no equilíbrio, harmonia e função do arco dentário. Nos casos não diagnosticados ou tratados inadequadamente podem ocorrer perturbações mecânicas, infecciosas ou neoplásicas. O prognóstico depende da posição do canino em relação às estruturas adjacentes e à possibilidade de movimentação ortodôntica. O presente trabalho aborda os principais fatores a serem considerados nos casos de caninos superiores permanentes impactados, tais como processo de erupção, etiologia, diagnóstico e uma forma de tração proposta para caninos impactados. Também será apresentado um caso clínico em que se optou pelo tratamento ortodôntico-cirúrgico, cuja técnica de tração tem-se mostrado bastante eficiente nos casos de impactação de caninos no palato.The teeth follow a favorable sequence of eruption on the development of a normal occlusion, but some disturbance of that mechanism at the period of transition of the mixed denture for the permanent one, may provoke alterations in the sequence or even in the eruption path, resulting in impactation of teeth. The permanent maxillary canine, after the third molars, is the most commonly impacted tooth, especially at the palatine area, even though enough space be present for its alignment in the dental

  9. Concomitant herpes simplex virus colitis and hepatitis in a man with ulcerative colitis

    Science.gov (United States)

    Phadke, Varun K.; Friedman-Moraco, Rachel J.; Quigley, Brian C.; Farris, Alton B.; Norvell, J. P.

    2016-01-01

    Abstract Background: Herpesvirus infections often complicate the clinical course of patients with inflammatory bowel disease; however, invasive disease due to herpes simplex virus is distinctly uncommon. Methods: We present a case of herpes simplex virus colitis and hepatitis, review all the previously published cases of herpes simplex virus colitis, and discuss common clinical features and outcomes. We also discuss the epidemiology, clinical manifestations, diagnosis, and management of herpes simplex virus infections, focusing specifically on patients with inflammatory bowel disease. Results: A 43-year-old man with ulcerative colitis, previously controlled with an oral 5-aminosalicylic agent, developed symptoms of a colitis flare that did not respond to treatment with systemic corticosteroid therapy. One week later he developed orolabial ulcers and progressive hepatic dysfunction, with markedly elevated transaminases and coagulopathy. He underwent emergent total colectomy when imaging suggested bowel micro-perforation. Pathology from both the colon and liver was consistent with herpes simplex virus infection, and a viral culture of his orolabial lesions and a serum polymerase chain reaction assay also identified herpes simplex virus. He was treated with systemic antiviral therapy and made a complete recovery. Conclusions: Disseminated herpes simplex virus infection with concomitant involvement of the colon and liver has been reported only 3 times in the published literature, and to our knowledge this is the first such case in a patient with inflammatory bowel disease. The risk of invasive herpes simplex virus infections increases with some, but not all immunomodulatory therapies. Optimal management of herpes simplex virus in patients with inflammatory bowel disease includes targeted prophylactic therapy for patients with evidence of latent infection, and timely initiation of antiviral therapy for those patients suspected to have invasive disease. PMID:27759636

  10. Herpes viruses and tumours in kidney transplant recipients. The role of immunosuppression.

    Science.gov (United States)

    Ponticelli, Claudio

    2011-06-01

    Herpes virus infections are frequent in renal transplant recipients. Some herpes viruses are not only responsible for life-threatening infections and renal graft injury but can also increase the risk of malignancy. Three herpes viruses, namely cytomegalovirus (CMV) or human herpes virus 5, Epstein-Barr virus (EBV) or herpes virus 4 and human herpes virus 8 (HHV8), may play an oncogenic role. The oncogenic role of CMV is controversial. However, there is growing evidence showing that CMV can infect cancer cells and favour their resistance to the immune system and chemotherapy. B cells infected by EBV can have uncontrolled proliferation eventually resulting in polyclonal polymorphic or monomorphic post-transplant lymphoproliferative diseases (PTLD), which are particularly frequent in children and in EBV-negative recipients. In some ethnicities, the carriers of HHV8 are susceptible to develop Kaposi's sarcoma after transplantation. The intensity of immunosuppression therapy plays a critical role in mediating infections from oncogenic herpes viruses. However, the type of immunosuppressive drugs can also influence the risk of virus-mediated neoplasias. An aggressive induction therapy aimed at depleting lymphocytes may favour the reactivation and dissemination of oncogenic herpes viruses, while anti-CD25 monoclonal antibodies have little impact on virus reactivation. Calcineurin inhibitors can increase the risk of viral infections and malignancy. Mycofenolate salts may perhaps protect from EBV-related PTLD. Finally, the inhibitors of the mammalian target of rapamycine may reduce the risk of viral disease by inhibiting the cascade of kinases that govern the proliferation and replication of oncogenic herpes viruses.

  11. Parâmetros de desempenho e carcaça de genótipos de frangos tipo caipira

    OpenAIRE

    Veloso,R.C.; Pires,A.V.; Torres Filho,R.A.; Pinheiro,S.R.F.; WinKelstroter,L.K.; Alcântara,D.C.; Cruz,C.C.D.C.S.

    2014-01-01

    Objetivou-se com este trabalho avaliar as características de desempenho e de carcaça de sete genótipos de frangos tipo caipira da linhagem Redbro. Foram utilizados 840 pintos de um dia, machos, distribuídos em delineamento inteiramente ao acaso, dos seguintes genótipos: Caboclo, Carijó, Colorpak, Gigante Negro, Pesadão Vermelho, Pescoço Pelado e Tricolor. Os frangos foram alojados em 28 boxes, sendo 30 frangos por boxe, em galpão de alvenaria com a...

  12. Diffusion-weighted MR imaging findings in a patient with herpes simplex encephalitis

    Energy Technology Data Exchange (ETDEWEB)

    Heiner, L. E-mail: heiner_lajos@freemail.hu; Demaerel, Ph

    2003-03-01

    Introduction: Herpes simplex meningoencephalitis is one of the most common viral central nervous system infection in adults. Early diagnosis is essential for treatment. Case report: We present a case of a 68-year-old female patient with herpes simplex infection. On admission, she was in severe clinical condition. Diffusion-weighted (DW) magnetic resonance imaging detected brain involvement better than conventional sequences. After acyclovir therapy, the patient fully recovered. Conclusion: DW magnetic resonance imaging is expected to provide a more sensitive imaging in herpes simplex patients than conventional sequences.

  13. Guillain-Barre syndrome presenting with sensory disturbance following a herpes virus infection: a case report

    Directory of Open Access Journals (Sweden)

    Ntziora Fotinie

    2011-12-01

    Full Text Available Abstract Introduction We present a case of an unusual clinical manifestation of Guillain-Barre syndrome following a pre-existing herpes virus infection. Although there have been several reports describing the co-existence of herpes virus infection and Guillain-Barre syndrome, we undertook a more in-depth study of the cross-reactivity between herpes viruses and recommend a follow-up study based on serology tests. Case presentation A 39-year-old healthy Caucasian man with Guillain-Barre syndrome presented to our facility initially with sensory disturbance, followed by an atypical descending pattern of clinical progression. On physical examination, our patient showed hot and cold temperature sensory disturbance under the T4 vertebrae level, symmetrically diminished muscle power mainly to his lower limbs, blurred vision, a loss of taste and paresis and diminished reflexes of his lower limbs. Serology test results for common viruses on hospital admission were positive for cytomegalovirus immunoglobulin M, cytomegalovirus immunoglobulin G, herpes simplex virus immunoglobulin M, herpes simplex virus immunoglobulin G, Epstein-Barr virus immunoglobulin M, and varicella zoster virus immunoglobulin G, borderline for Epstein-Barr virus immunoglobulin G and negative for varicella zoster virus immunoglobulin M. At one month after hospital admission his test results were positive for cytomegalovirus immunoglobulin M, cytomegalovirus immunoglobulin G, herpes simplex virus immunoglobulin G, Epstein-Barr virus immunoglobulin G, varicella zoster virus immunoglobulin G, borderline for herpes simplex virus immunoglobulin M and negative for Epstein-Barr virus immunoglobulin M and varicella zoster virus immunoglobulin M. At his six month follow-up, tests were positive for cytomegalovirus immunoglobulin G, herpes simplex virus immunoglobulin M, herpes simplex virus immunoglobulin G, Epstein-Barr virus immunoglobulin G and varicella zoster virus immunoglobulin G and

  14. Herpes Zoster Infections in SLE in a University Hospital in Saudi Arabia: Risk Factors and Outcomes

    Directory of Open Access Journals (Sweden)

    Afsar Sayeeda

    2010-01-01

    (0/23. None of the patients had postherpetic neuralgia or bacterial super infection. Immunosuppressive medications were discontinued at the time of diagnosis of Zoster in 19 of 32 patients and all patients received antiviral medications.There were no permanent neurologic deficits or deaths. We conclude that Herpes Zoster infections occur at increased frequency among patients with SLE and carry significant morbidity. Immunosuppressive therapy and severe manifestations of lupus may be risk factors for the development of Herpes Zoster although not necessarily at the time of disease flare or immunosuppressive therapy. Our study suggests that although Herpes Zoster occurs frequently in patients with SLE, it has a relatively benign course.

  15. OTROS TIPOS ESPECÍFICOS DE DIABETES MELLITUS

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    DRA. M. Gabriela Sanzana G.

    2016-03-01

    En las “Diabetes Atípicas” (no incluidas en la clasificación ADA, se mencionan la DM tipo 2 en niños y adolescentes, favorecida por el aumento de la obesidad y del sedentarismo; la diabetes propensa a la cetosis, que debutan en cetoacidosis, con etiopatogenia y evolución de DM2; los Latent Autoinmune Diabetes of Adults (LADA, DM tipo 1 de lenta aparición y la diabetes postrasplante.

  16. Fenótipo Rett em paciente com cariótipo XXY: relato de caso

    OpenAIRE

    SCHWARTZMAN,JOSÉ SALOMÃO; SOUZA,ANGELA MARIA COSTA DE; FAIWICHOW,GUIDO; HERCOWITZ,LUIZ HENRIQUE

    1998-01-01

    Relatamos o caso de um menino com cariótipo XXY que apresenta desordem neurológica progressiva com início por volta dos 11 meses de idade, com estagnação do desenvolvimento seguida de regressão. A criança apresenta, ainda, movimentos estereotipados de mãos, apraxia manual e microcefalia. Investigações não constataram presença de qualquer condição neurológica ou sistêmica definida que pudesse ser apontada como possível etiologia para o quadro descrito. Trata-se de menino com alterações fenotíp...

  17. Psychiatric aspects of herpes simplex encephalitis, tick-borne encephalitis and herpes zoster encephalitis among immunocompetent patients.

    Science.gov (United States)

    Więdłocha, Magdalena; Marcinowicz, Piotr; Stańczykiewicz, Bartłomiej

    2015-01-01

    The psychopathological symptoms occurring in the course of diseases associated with infections are often initially isolated and non-characteristic, and may cause diagnostic difficulties. Moreover, such disorders tend to be less responsive to psychiatric management. Among possible causes such as trauma, neoplasm and vascular changes, inflammatory changes of the brain as a result of a viral infection should also be considered. There were 452 registered cases of viral encephalitis in Poland in 2010, and although not very prevalent they remain a severe and life-threatening condition. What is more, the frequently occurring neurological and psychiatric complications of viral encephalitis often result in permanent disabilities, causing a significant decrease in the quality of life. This article presents the three types of encephalitis that are most prevalent among immunocompetent patients in Poland, i.e. herpes simplex encephalitis (HSE), tick-borne encephalitis (TBE) and herpes zoster encephalitis (HZE). The psychopathology of the acute phase of the infection, the residual symptoms, features apparent in imaging studies and some neuropathological aspects are also presented. The paper also focuses on psychiatric aspects of the diagnostics and treatment of the described conditions. The clinical pictures of these infections are quite specific, although they cover a wide range of symptoms, and these characteristic features are described. The aim of this review is also to show the significance of thorough diagnostics and a multidisciplinary approach to patients with viral CNS infections.

  18. Potential risk of developing herpes simplex encephalitis in patients treated with sildenafil following primary exposure to genital herpes.

    Science.gov (United States)

    Goren, A; Mccoy, J; Kovacevic, M; Situm, M; Lonky, N

    2017-01-01

    Herpes simplex encephalitis (HSE) is associated with significant mortality and morbidity. As a consequence of HSE, up to 75% of infected individuals die or experience irreversible neurological damage. While the pathogenesis of the disease is unknown, it is traditionally hypothesized that the viral infection occurs by neuronal transmission directly from peripheral sites. Non-neuronal modes of infection have generally been overlooked as the brain is protected by the blood-brain-barrier (BBB). The BBB poses an effective barrier to pathogens as well as to drugs such as chemotherapies. In the pursuit to deliver chemotherapeutic agents to the brain, several studies demonstrated that phosphodiesterase type 5 (PDE5) inhibitors, such as sildenafil, may increase the permeability of the BBB enabling successful delivery of chemotherapeutic agents to the brain. In this communication, we report a case of HSE infection in a 62-year-old man, which we suspect was facilitated by the use of sildenafil during a primary genital herpes simple virus (HSV) infection. Due to large number of patients treated with PDE5 inhibitors for erectile dysfunction and the high incidence of genital HSV infection in the general population, a larger study should examine the potential risk of developing HSE in patients treated with PDE5 inhibitors.

  19. Esclerose lateral amiotrófica e herpes vírus. Relato de um caso curioso: uma associação casual ou causal? Amyotrophic lateral sclerosis and herpes virus. A curious case report: a cause or casual association?

    Directory of Open Access Journals (Sweden)

    JOÃO ELIEZER FERRI-DE-BARROS

    1998-06-01

    Full Text Available OBJETIVO: Apresentar o relato de um caso curioso de esclerose lateral amiotrófica (ELA. CASO: Homem de 47 anos que apresentava déficit de força nos membros superiores evoluindo há 4 anos. A eletroneuromiografia era compatível a ELA, forma de Vulpian-Bernardt. O estudo do líquido cefalorraqueano (LCR mostrava processo inflamatório e positividade das reações para Herpes vírus I e II. O estudo do LCR, do soro sanguíneo e da barreira hemato-encefálica sugeria imunoprodução local para Herpes vírus tipo I. A ressonância nuclear magnética sugeria mielopatia cística ou seringomielia em medula cervical estendendo-se nos espaços C2 a C4. O paciente foi tratado com aciclovir endovenoso por 21 dias. Até dois meses após, o paciente não foi submetido a novos exames subsidiários para controle. DISCUSSÃO: Até o momento atual, a doença ELA não tem tratamento medicamentoso específico. A noção da existência de "síndrome esclerose lateral amiotrófica" associada a etiologias diversas pode contribuir para o tratamento de alguns doentes.OBJECTIVE: To present a curious case of amyotrophic lateral sclerosis (ALS. CASE: A forty-seven year old man claimed of paresis in the arms since four years. The electrical study of the muscles and nerves diagnosis was ALS, type Vulpian-Bernardt. The cerebrospinal fluid study revealed an inflammatory process and the positivity of immulogical reactions for Herpes simplex I. The blood-brain barrier study showed the possibility that immulogical response for Herpes simplex I was produced in the spinal fluid space. A magnetic resonance suggested cystic myelopathy of cervical spinal cord expanding from C2 to C4. The patient received endovenous acyclovir for 21 days. Until two months after the medication we did not submit the patient to other subsidiary examinations. DISCUSSION: Until now there is no specific drug treatment for ALS. The notion that there is a "syndrome of ALS" related with various causes may

  20. Concurrent hyphema and orbital apex syndrome following herpes zoster ophthalmicus in a middle aged lady

    Directory of Open Access Journals (Sweden)

    Khairuddin Othman

    2017-01-01

    Conclusion: Herpes zoster ophthalmicus is an uncommon ocular presentation. Managing two concurrent complications; persistent total hyphema and orbital apex syndrome is a challenging clinical situation. Early diagnosis and prompt treatment are essential to prevent potential blinding situation.

  1. Efficacy of cikloferon liniment in complex therapy of secondary herpes associated with psoriasis

    National Research Council Canada - National Science Library

    Shuldyakov A.A; Barchatova Т.S; Lisko О.В; Satarova S.A; Perminova Т.A; Tsareva T.D

    2013-01-01

    .... Materials and methods: 30 patients were included in the study divided into two groups. In the 1st group the patients received standard treatment for herpes and two daily applications of cikloferon liniment for seven days...

  2. Herpetofauna Inventory Survey Routes for 2001 Pipe Spring National Monument, Arizona(pisp_herp01)

    Data.gov (United States)

    National Park Service, Department of the Interior — This shapefile maps the survey routes of the Herp 2001 Inventory crews for Pipe Springs National Monument. The other parks visited were Bryce Canyon, Capitol Reef,...

  3. Herpetofauna Inventory Survey Routes for 2002 Pipe Spring National Monument, Arizona (pisp_herp02)

    Data.gov (United States)

    National Park Service, Department of the Interior — This shapefile maps the survey routes of the Herp 2002 Inventory crews for Pipe Spring National Monument. The other parks visited were Arches, Bryce Canyon, Capitol...

  4. Diagnosis of genital herpes simplex virus infection in the clinical laboratory

    National Research Council Canada - National Science Library

    LeGoff, Jérôme; Péré, Hélène; Bélec, Laurent

    2014-01-01

    .... However, HSV PCR, with its consistently and substantially higher rate of HSV detection, could replace viral culture as the gold standard for the diagnosis of genital herpes in people with active...

  5. In vitro antiviral activity of antimicrobial peptides against herpes simplex virus 1, adenovirus, and rotavirus

    National Research Council Canada - National Science Library

    Carriel-Gomes, Márcia Cristina; Kratz, Jadel Müller; Barracco, Margherita Anna; Bachére, Evelyne; Barardi, Célia Regina Monte; Simões, Cláudia Maria Oliveira

    2007-01-01

    .... This paper describes the in vitro evaluation of the cytotoxicity and antiviral activity of nine peptides with different structures and origins against herpes simplex virus type 1, human adenovirus...

  6. Immunization against Genital Herpes with a Vaccine Virus That has Defects in Productive and Latent Infection

    Science.gov (United States)

    da Costa, Xavier J.; Jones, Cheryl A.; Knipe, David M.

    1999-06-01

    An effective vaccine for genital herpes has been difficult to achieve because of the limited efficacy of subunit vaccines and the safety concerns about live viruses. As an alternative approach, mutant herpes simplex virus strains that are replication-defective can induce protective immunity. To increase the level of safety and to prove that replication was not needed for immunization, we constructed a mutant herpes simplex virus 2 strain containing two deletion mutations, each of which eliminated viral replication. The double-mutant virus induces protective immunity that can reduce acute viral shedding and latent infection in a mouse genital model, but importantly, the double-mutant virus shows a phenotypic defect in latent infection. This herpes vaccine strain, which is immunogenic but has defects in both productive and latent infection, provides a paradigm for the design of vaccines and vaccine vectors for other sexually transmitted diseases, such as AIDS.

  7. Molecular Characterization of Prostate Cancer Cell Oncolysis by Herpes Simplex Virus ICP0 Mutants

    National Research Council Canada - National Science Library

    Mossman, Karen

    2006-01-01

    .... Briefly, the goals of the proposal were to characterize the oncolytic capacity of Herpes simplex virus type 1 ICP0 mutants in prostate cancer cells given the relationship between ICP0 and two tumor...

  8. A Fusogenic Oncolytic Herpes Simplex Virus for Therapy of Advanced Ovarian Cancer

    National Research Council Canada - National Science Library

    Zhang, Xiaoliu

    2004-01-01

    The tasks that were originally planned for the first year of this 3 year project are to demonstrate that the fusogenic oncolytic herpes simplex viruses are potent anti-tumor agents for advanced ovarian cancer...

  9. Molecular Characterization of Prostate Cancer Cell Oncolysis by Herpes Simplex Virus ICP0 Mutants

    National Research Council Canada - National Science Library

    Mossman, Karen

    2005-01-01

    .... Briefly, the goals of the proposal were to characterize the oncolytic capacity of Herpes simplex virus type 1 ICPO mutants in prostate cancer cells given the relationship between ICPO and two tumor...

  10. Efeito do fator de crescimento epidermal (EGF na maturação in vitro de oócitos caninos

    Directory of Open Access Journals (Sweden)

    Leda Maria Costa Pereira

    2014-09-01

    Full Text Available Este trabalho teve o objetivo de avaliar a influência do EGF na maturação in vitro (MIV de cadelas. Realizou-se o transporte dos ovários em solução de cloreto de sódio 0,9%, que foram seccionados em solução salina fosfato tamponado (PBS e os complexos cumulus oócito (COCs selecionados em meio de cultura de tecidos (TCM 199 suplementado com HEPES. Foram coletados 405 oócitos grau 1 de cadelas em anestro e diestro. Os oócitos provenientes das duas fases do ciclo estral foram submetidos a dois tratamentos: meio com adição de 10 ηg/mL do fator de crescimento epidermal (EGF (T e meio sem suplementação (C. Depois de 72 horas de maturação, os COCs foram desnudados, fixados e corados com HOESCHT 33342 para avaliação da maturação nuclear. Os oócitos obtidos dos ovários da fase de diestro do grupo T demonstraram maior porcentagem (18,8% de oócitos no estágio de metáfase II (M-II, em relação ao grupo C (1,3% (p < 0,01. Nos oócitos obtidos da fase de anestro houve diferença (p < 0,05 entre os grupos, observando-se menor parcela (4,1% de oócitos no estágio de vesícula germinativa (VG no grupo T, quando comparado ao grupo C (16,1%. Comparando-se as diferentes fases reprodutivas, em meios suplementados com EGF, foi observada diferença (p < 0,05 apenas nos oócitos obtidos da fase de diestro em relação ao estágio de M-II. Dessa maneira, a suplementação no meio de maturação na concentração de 10 ηg/mL, neste estudo, exerceu influência positiva apenas na MIV de oócitos caninos oriundos da fase de diestro, incrementando os índices de M-II nessa espécie.

  11. Inquérito canino em foco recente de leishmaniose tegumentar no Município de Sabará, região metropolitana de Belo Horizonte

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    Valéria Maria Azeredo Passos

    1996-08-01

    Full Text Available Em 1992, foi obsewada lesão cutânea por Leishmania em um cão do município de Sabará, Minas Gerais, onde já haviam sido registrados casos humanos de leishmaniose tegumentar. O parasita foi caracterizado como pertencente ao subgênero Viannia, ao qual pertence a Leishmania braziliensis, principal espécie encontrada tia região sudeste do Brasil. Com o objetivo de determinar o papel do cão no ciclo de transmissão da doença, foi realizado um inquérito canino na área. Foram examinados 631 cães, sendo a soroprevalência para leishmaniose igual a 3,2%. Foi observada a proximidade ou presença no mesmo domicílio de cães e pessoas doentes. Este aspecto fala a favor da transmissão domiciliar ou peridomiciliar, com o cão infectado podendo atuar como fator de risco nesta área periurbana. Entretanto, a baixa soroprevalência encontrada deve-se provavelmente ao pequeno papel deste animal na transmissão da doença neste foco recente da doença.In 1992, a dog naturally infected with Leishmania was found in a periurban area of Sabará, State of Minas Gerais, where human cutaneous leishmaniasis had been previously described. The parasite was classified as Leishmania, subgenus Viannia, which L. braziliensis, the main species of parasite present in the southeast Brazil, also belongs. In order to assess the importance of the dog in the transmission cycle of the disease, a canine survey was undertaken. Six hundred thirty-one dogs were examined and the prevalence of seropositive dogs for crude Leishmania amazonensis antigen was 3.2%. The presence of infected people and seropositive dogs either near or in the same house was observed. This fact suggests some transmission in the domiciliar environment, with the dogs being a risk factor for human infection in that periurban area. In the other hand, the low percentage of seropositive dogs points towards a secondary importance of these animals in the transmission of Leishmaniasis in that recentfocus of

  12. Efeito da centrifugação sobre a qualidade do sêmen canino Effect of centrifugation on quality of canine semen

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    I.C.N. Cunha

    2009-02-01

    Full Text Available Avaliou-se o efeito da centrifugação sobre a viabilidade do sêmen canino e compararam-se três meios de diluição pré-centrifugação. Utilizaram-se 10 ejaculados completos de 10 cães que, após a avaliação inicial, foram divididos em quatro porções (grupos. Uma das amostras, não centrifugada, formou o grupo-controle; as outras foram diluídas em três diferentes meios e centrifugadas a 800 x g por 15 minutos, formando os grupos: CPSA - constituído por sêmen centrifugado em plasma seminal autólogo; CLG - sêmen centrifugado em meio à base de leite desnatado e glicose (LG; e CPer- sêmen centrifugado em gradientes de Percoll (45% e 90%. Após a centrifugação e a eliminação do sobrenadante, procedeu-se à ressuspensão de todas as porções do ejaculado em LG e à imediata avaliação quanto à motilidade, vigor, aglutinação espermática e integridade das membranas espermáticas. Todas as suspensões foram, então, incubadas a 37ºC por 30 minutos e reavaliadas. O processo de centrifugação não causou danos aos espermatozoides e a centrifugação em meio LG melhorou a viabilidade espermática.The effect of the centrifugation process on canine sperm viability was evaluated using three different precentrifugation extenders in the process. After an initial evaluation, ten complete ejaculates from ten dogs were used and subdivided in four groups. One sample of semen was not centrifuged and was used as control and the remaining samples of semen were diluted in three different extenders and centrifuged at 800 x g per 15 minutes, performing groups: CPSA- centrifuged in autologous seminal fluid, CLGcentrifuged in skim milk plus glucose extender (LG, and CPer- centrifuged under Percoll gradient (45% and 90%. After centrifugation, the resulting pellets were diluted in LG and evaluated for motility, viability, sperm agglutination, and spermatic membrane integrity. All the samples were incubated at 37ºC for 30 minutes and the

  13. Transient natural killer deficiency in a boy with herpes simplex virus-associated recurrent erythema multiforme.

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    Messina, Maria Francesca; Cannavò, Serafinella Patrizia; Aversa, Salvatore; De Luca, Filippo

    2011-07-01

    Erythema multiforme is characterized by itching macules, papules and bullae, symmetrically distributed on the dorsum of the hands. They can follow the administration of several drugs or infections with various agents, and in particular with herpes simplex virus. The recurrent variant is very rare, especially in the paediatric age group. We describe the case of a male adolescent with recurrent erythema multiforme caused by herpes virus and transient natural killer deficiency.

  14. Herpes simplex virus type 2: Cluster of unrelated cases in an intensive care unit.

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    Troché, Gilles; Marque Juillet, Stephanie; Burrel, Sonia; Boutolleau, David; Bédos, Jean-Pierre; Legriel, Stephane

    2016-10-01

    Herpes simplex viruses, which are associated with various clinical manifestations, can be transmitted to critically ill patients from other patients or health care staff. We report an apparent outbreak of mucocutaneous herpes simplex virus 2 infections (5 cases in 10 weeks). An epidemiologic investigation and genotype analysis showed no connections among the 5 cases. Copyright © 2016 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

  15. Herpes zoster reactivation after extracorporeal shock wave lithotripsy: A case report

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    Krishnamoorthy Hariharan

    2016-01-01

    Full Text Available Herpes zoster is a reactivated varicella-zoster virus (VZV infection of the sensory nerve ganglion, peripheral nerve, and its branches. Mechanical trauma to the nervous system can reactivate VZV. It is well known that extracorporeal shock wave lithotripsy (SWL can produce mechanical damage to the tissue. We report a rare case of herpes zoster reactivation after SWL for treatment of 1.2 cm size renal stone in a 63-year-old male patient.

  16. Prevention and management of neonatal herpes simplex virus infections

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    Allen, Upton D; Robinson, Joan L

    2014-01-01

    Human herpes simplex virus (HSV) infection in neonates can result in devastating outcomes, including mortality and significant morbidity. All infants are potentially at risk for neonatal HSV infection. This position statement reviews epidemiology, transmission and risk factors, with a focus on intrapartum infection. It considers diagnosis and prognosis according to infection category, along with testing modalities and limitations. Recommendations for managing newborns known to have been exposed intrapartum to HSV are based on expert opinion because a randomized trial to compare management options is not feasible. Guidance is provided for the empirical management of infants with suspected clinical sepsis, including those who do not respond to antibacterial therapy. The present statement replaces a 2006 position statement by the Canadian Paediatric Society. PMID:24855418

  17. Neonatal Herpes Simplex Viral Infections and Acyclovir: An Update

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    Holmes, Amy P.

    2017-01-01

    Neonatal herpes simplex virus (HSV) infections have high morbidity and mortality rates. Optimization of treatment and prevention strategies are imperative to improve the care and outcomes of neonates infected with HSV. Management of HSV includes reducing neonatal transmission, treating acute infections, and limiting adverse neurodevelopmental outcomes and future cutaneous outbreaks after acute infections. Transmission risk may be affected by route of delivery and maternal suppressive therapy. Neonatal HSV infections are divided into 3 categories: localized skin, eyes, or mouth; localized central nervous system; or disseminated infections. Parenteral acyclovir, the pharmacologic agent of choice, is used when treating each type of infection. However, dosage strategies and durations of therapy may vary based on disease state severity, presentation, and patient characteristics. Oral acyclovir may be used as suppressive therapy after acute treatment completion in specific neonatal populations, reducing long-term adverse neurodevelopmental outcomes and future skin eruptions. The mortality rate remains high even with treatment. PMID:28469532

  18. Herpes Zoster Cervical Myelitis in a Young Adult

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    Cheng-Chia Lee

    2010-11-01

    Full Text Available Varicella zoster virus infection, which causes chickenpox and herpes zoster (HZ, is not uncommon in the general population. Varicella zoster virus can be latent in cranial nerve or dorsal root ganglia, and reactivate several decades later to produce vesicles with post-herpetic neuralgia. HZ myelitis usually occurs in elderly or immunocompromised patients. We report here a case of HZ myelitis of the cervical spinal cord in a 35-year-old woman who was immunocompetent. Cervical myelitis developed 1 month after the eruption of vesicles. Pure sensation loss was limited initially from the C2 to T1 dermatomes, but later progressed to lower limb sensory loss and sphincter function impairment. The patient's motor function was also mildly affected. Despite the initial rapid neurological deterioration, the symptoms dramatically improved after 5 days of parenteral acyclovir and steroid administration with rehabilitation. We therefore propose that early medical intervention is necessary for better and earlier recovery.

  19. Herpes zoster ophthalmicus with associated vasculopathy causing stroke.

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    Antia, Camila; Persad, Leah; Alikhan, Ali

    2017-07-15

    Varicella zoster virus (VZV) is an exclusively human, double-stranded DNA virus. Primary infection causes varicella (chickenpox); later the virus becomes dormant in the dorsal root, cranial nerve, and autonomic ganglia along the entire span of the nervous system, retaining the capacity to reactivate and cause a variety of dermal and neurological complications. Recently there has been increasing recognition, both clinically and epidemiologically, of the relationship between VZV and subsequent strokes. Herein, we describe a case of a previously healthy individual with reactivation of VZV causing herpes zoster opthtalmicus along with devastating multifocal vasculopathy. It is crucial for dermatologists to recognize the dermatomal vesicular eruption in this high risk area to aid in prompt diagnosis in an effort to improve clinical prognosis.

  20. Herpes Zoster in a 3-month-old infant

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    Duarte Malveiro

    2015-12-01

    Full Text Available Introduction: Herpes Zoster (HZ is rare in infancy and results from reactivation of varicella-zoster virus, latent in the dorsal root ganglia of sensory or cranial nerves after primary infection (chickenpox. Case Report: We describe the case of an healthy infant, three months old, without previous clinical symptoms of chickenpox, in spite of having contacted with the disease at two weeks of life. She was hospitalized for vesicular-papular rash involving unilaterally dermatomes L4 and L5 and was treated with acyclovir with good clinical outcome. Conclusion: The immaturity of the immune system and the interference of maternal antibodies contribute to the manifestation of HZ in the first year of life. In a previously healthy child it is not recommended the exclusion of underlying immunodeficiency or malignant disease.