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Sample records for hermine hug-hellmuth geniuna

  1. Hermine Hug-Hellmuth, the first child psychoanalyst: legacy and dilemmas.

    Science.gov (United States)

    Plastow, Michael

    2011-06-01

    Despite being the first psychoanalyst of children, Hermine Hug-Hellmuth's history and writings remain relatively unknown. This paper endeavours to examine the way in which the history of the psychoanalysis of children is marked by the history of its protagonists. In particular, Hug-Hellmuth's treatment of children is divided between an educational approach and a more properly psychoanalytical aspect. Her theory and practice heavily influenced the directions taken after her, in particular by Anna Freud and Melanie Klein, even if this influence is essentially unacknowledged by these authors. Hug-Hellmuth's contribution to the psychoanalysis of children and consequently to child psychiatry are considerable and include technical innovation with the introduction of play into the treatment of children, the elaboration of the place of the analyst in regard to the child and notably the establishment of the place of the parents in regard to the treatment of the child. It is proposed that the very duality of her approach is what allowed her to be able to distinguish the place of the parent from that of the analyst. Nonetheless, her insistence on the place of education within the treatment and its effects on later theorists continue to raise dilemmas today.

  2. HUG - the Hydrogen Utility Group

    International Nuclear Information System (INIS)

    Tinkler, M.

    2006-01-01

    The Hydrogen Utility Group (HUG) was formally established in October 2005 by a group of leading electric utilities with a common interest in sharing hydrogen experiences and lessons learned. HUG's Mission Statement is: 'To accelerate utility integration of promising hydrogen energy related business applications through the coordinated efforts and actions of its members in collaboration with key stakeholders, including government agencies and utility support organizations.' In February 2006, HUG members presented a briefing to the US Senate Hydrogen and Fuel Cell Caucus in Washington, DC, outlining the significant role that the power industry should play in an emerging hydrogen economy. This presentation provides an overview of that briefing, summarizing the HUG's ongoing interests and activities

  3. Huggy Pajama: A Remote Interactive Touch and Hugging System

    Science.gov (United States)

    Cheok, Adrian David

    Huggy Pajama is a novel wearable system aimed at promoting physical interaction in remote communication between parent and child. This system enables parents and children to hug one another through a hugging interface device and a wearable, hug reproducing pajama connected through the Internet. The hug input device is a small, mobile doll with an embedded pressure sensing circuit that is able to accurately sense varying levels of pressure along the range of human touch produced from natural touch. This device sends hug signals to a haptic jacket that simulates the feeling of being hugged to the wearer. It features air pocket actuators that reproduce hug sensations, heating elements to produce warmth that accompanies hugs, and a color changing pattern and accessory to indicate distance of separation and communicate expressions. In this chapter, we present the system design of Huggy Pajama. We also show results from quantitative and qualitative user studies which show the effectiveness of the system simulating an actual human touch. Results also indicate an increased sense of presence between parents and children when used as an added component to instant messaging and video chat communication.

  4. Tres obras del equipo de arquitectos Hellmuth, Obata & Kassabaum/EE.UU.

    Directory of Open Access Journals (Sweden)

    Editorial, Equipo

    1982-02-01

    Full Text Available Not available.En este artículo se describen tres obras recientes del equipo de arquitectos Hellmuth, Obata y Kassabaum. La primera corresponde al Centro Cívico Decatur que, en un único edificio, organiza tres funciones totalmente distintas: una pista de patinaje sobre hielo, un teatro y el Ayuntamiento de la ciudad. La segunda, la Biblioteca de la Universidad de Western, Illinois, consta de cuatro pabellones de cinco alturas desarrollados en torno a un amplio espacio central de comunicaciones y servicios. La última trata de la ampliación, mediante dos nuevos edificios, de un antiguo hospital y su adaptación a las nuevas funciones de enseñanza que tenía que satisfacer.

  5. Attitude coordination of multi-HUG formation based on multibody system theory

    Science.gov (United States)

    Xue, Dong-yang; Wu, Zhi-liang; Qi, Er-mai; Wang, Yan-hui; Wang, Shu-xin

    2017-04-01

    Application of multiple hybrid underwater gliders (HUGs) is a promising method for large scale, long-term ocean survey. Attitude coordination has become a requisite for task execution of multi-HUG formation. In this paper, a multibody model is presented for attitude coordination among agents in the HUG formation. The HUG formation is regarded as a multi-rigid body system. The interaction between agents in the formation is described by artificial potential field (APF) approach. Attitude control torque is composed of a conservative torque generated by orientation potential field and a dissipative term related with angular velocity. Dynamic modeling of the multibody system is presented to analyze the dynamic process of the HUG formation. Numerical calculation is carried out to simulate attitude synchronization with two kinds of formation topologies. Results show that attitude synchronization can be fulfilled based on the multibody method described in this paper. It is also indicated that different topologies affect attitude control quality with respect to energy consumption and adjusting time. Low level topology should be adopted during formation control scheme design to achieve a better control effect.

  6. Hugging fusion and related topics

    Energy Technology Data Exchange (ETDEWEB)

    Iwamoto, Akira [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1997-07-01

    An important problem related to the synthesis of very heavy nuclides by fusion of two heavy-ions is the extra push effect. To avoid it, we propose a hugging fusion, which is the fusion of two well-deformed heavy-ions. (author)

  7. The Hug-up Test: A New, Sensitive Diagnostic Test for Supraspinatus Tears

    Directory of Open Access Journals (Sweden)

    Yu-Lei Liu

    2016-01-01

    Full Text Available Background: The supraspinatus tendon is the most commonly affected tendon in rotator cuff tears. Early detection of a supraspinatus tear using an accurate physical examination is, therefore, important. However, the currently used physical tests for detecting supraspinatus tears are poor diagnostic indicators and involve a wide range of sensitivity and specificity values. Therefore, the aim of this study was to establish a new physical test for the diagnosis of supraspinatus tears and evaluate its accuracy in comparison with conventional tests. Methods: Between November 2012 and January 2014, 200 consecutive patients undergoing shoulder arthroscopy were prospectively evaluated preoperatively. The hug-up test, empty can (EC test, full can (FC test, Neer impingement sign, and Hawkins-Kennedy impingement sign were used and compared statistically for their accuracy in terms of supraspinatus tears, with arthroscopic findings as the gold standard. Muscle strength was precisely quantified using an electronic digital tensiometer. Results: The prevalence of supraspinatus tears was 76.5%. The hug-up test demonstrated the highest sensitivity (94.1%, with a low negative likelihood ratio (NLR, 0.08 and comparable specificity (76.6% compared with the other four tests. The area under the receiver operating characteristic curve for the hug-up test was 0.854, with no statistical difference compared with the EC test (z = 1.438, P = 0.075 or the FC test (z = 1.498, P = 0.067. The hug-up test showed no statistical difference in terms of detecting different tear patterns according to the position (χ2 = 0.578, P = 0.898 and size (Fisher′s exact test, P > 0.999 compared with the arthroscopic examination. The interobserver reproducibility of the hug-up test was high, with a kappa coefficient of 0.823. Conclusions: The hug-up test can accurately detect supraspinatus tears with a high sensitivity, comparable specificity, and low NLR compared with the conventional

  8. Diagnóstico clínico da ruptura do tendão subescapular com a manobra semiológica bear hug Clinical diagnosis of subscapularis tendon tear using the bear hug semiological maneuver

    Directory of Open Access Journals (Sweden)

    Márcio Schiefer

    2012-10-01

    Full Text Available OBJETIVO: Avaliar a manobra bear hug no diagnóstico clínico da lesão do tendão subescapular e compará-la com manobras previamente descritas (lift-off, Napoleão e belly press. MÉTODOS: Foram analisados 49 pacientes com lesão do manguito rotador, submetidos à artroscopia para reparo da lesão e avaliados previamente pelas manobras semiológicas citadas. RESULTADOS: Os valores diagnósticos obtidos para o teste bear hug foram os seguintes: sensibilidade = 75%; especificidade = 56%; VPP = 62%; VPN = 70%; acurácia = 65%. CONCLUSÃO: Os maiores valores de sensibilidade e valor preditivo negativo foram obtidos com o bear hug. O maior valor de especificidade foi encontrado no teste lift-off. O teste belly press forneceu os maiores valores de especificidade, valor preditivo positivo e acurácia.OBJECTIVE: To evaluate the Bear Hug maneuver for clinically diagnosing subscapularis tendon tears, and compare this with other maneuvers described previously (Lift-off, Napoleon and Belly Press. METHODS: Forty-nine patients with rotator cuff injuries who had undergone arthroscopy to repair the injury and had previously been assessed using the semiological maneuvers mentioned above were evaluated. RESULTS: The diagnostic values obtained for the Bear Hug test were as follows: sensitivity 75%, specificity 56%, positive predictive value 62%, negative predictive value 70% and accuracy 65%. CONCLUSION: The highest sensitivity and negative predictive value values were obtained with the Bear Hug test. The highest specificity value was seen with the Lift-off test. The Belly press test gave the greatest specificity, positive predictive and accuracy values.

  9. HUG sets up an emergency operations centre on the CERN site

    CERN Multimedia

    Antonella Del Rosso

    2015-01-01

    Discussions between CERN and the Hôpitaux universitaires de Genève (HUG), under the aegis of the Swiss authorities, have resulted in the setting-up of an emergency operations centre on the CERN site. This will be the operations base for an emergency doctor, a medical emergency vehicle and a driver. Located on the Swiss part of the Meyrin site, close to Building 57, it will be inaugurated on 20 May.   SMUR team based at CERN. CERN’s medical staff and fire-fighters dispense first aid but in medical emergencies they are obliged to call on outside services to treat and transfer patients to hospital. In the Canton of Geneva, this service is provided by HUG via the 144 emergency line. But HUG is based on the eastern side of Geneva, a long way from CERN, and response times can be substantial. In order to improve the safety of the growing number of people on the site, CERN asked Switzerland, as one of its Host States, to help it reduce the medical emergency response t...

  10. EVALUATION OF THE STRUCTURAL FUNDS ABSORPTION RATE BY MEANS OF THE HERMIN MODEL

    Directory of Open Access Journals (Sweden)

    Opritescu Elena Madalina

    2012-07-01

    Full Text Available The main objective of this article is to highlight the main method that could quantify the impact of the structural funds on the Gross Domestic Product. I also presented the regional disparities situation and the European funds absorption rate. The HERMIN model has been designed considering the evolution of macro-variables throughout transition and pre-accession process, as well as out of the need to analyze the gradual alignment of Romania’s economic policies to those of EU. The fact that, initially, the HERMIN model was designed for the European Union’s less developed economies represented the cornerstone in choosing it, as it was the case for Romania, too. However, the quantitative evaluation must always be accompanied by a qualitative evaluation, in order to comprise factors which cannot be measured by the econometrical modeling. For this purpose, when the results of econometrical model based evaluation are used, it is important to be aware of the fact that models simplify reality, no matter the impressive mathematical calculations they employ. Also, we must not omit the fact that Romania’s major development needs and the current economic context imperatively demand a high as possible level of structural funds absorption, as well as their efficient use, meant to generate a significant impact at a national, regional and local level. One of the main instruments employed to sustain economic growth, while also reducing disparities between regions is represented by the structural funds. These funds, consisting in financial contributions of the member states, according to their level of development, are redistributed in compliance with an extremely complex regulating and procedural frame, to those EU states of regions which are fallen behind from a social and economical development perspective Nevertheless, when absorption capacity of a member state is evaluated, the used percentage from the allocated funds is not the only

  11. Cytoplasmic localization of Hug1p, a negative regulator of the MEC1 pathway, coincides with the compartmentalization of Rnr2p–Rnr4p

    Energy Technology Data Exchange (ETDEWEB)

    Ainsworth, William B. [Cain Department of Chemical Engineering, Louisiana State University, Baton Rouge, LA 70803 (United States); Hughes, Bridget Todd; Au, Wei Chun; Sakelaris, Sally [Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 (United States); Kerscher, Oliver [Biology Department, The College of William and Mary, Williamsburg, VA 23185 (United States); Benton, Michael G., E-mail: benton@lsu.edu [Cain Department of Chemical Engineering, Louisiana State University, Baton Rouge, LA 70803 (United States); Basrai, Munira A., E-mail: basraim@mail.nih.gov [Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 (United States)

    2013-10-04

    Highlights: •Hug1p overexpression sensitizes wild-type cells to DNA damage and hydroxyurea (HU). •Expression of Hug1p in response to HU treatment is delayed relative to Rnr3p. •MEC1 pathway genes are required for cytoplasmic localization of Hug1p. •Hug1p subcellular compartmentalization to the cytoplasm coincides with Rnr2p–Rnr4p. -- Abstract: The evolutionarily conserved MEC1 checkpoint pathway mediates cell cycle arrest and induction of genes including the RNR (Ribonucleotide reductase) genes and HUG1 (Hydroxyurea, ultraviolet, and gamma radiation) in response to DNA damage and replication arrest. Rnr complex activity is in part controlled by cytoplasmic localization of the Rnr2p–Rnr4p subunits and inactivation of negative regulators Sml1p and Dif1p upon DNA damage and hydroxyurea (HU) treatment. We previously showed that a deletion of HUG1 rescues lethality of mec1Δ and suppresses dun1Δ strains. In this study, multiple approaches demonstrate the regulatory response of Hug1p to DNA damage and HU treatment and support its role as a negative effector of the MEC1 pathway. Consistent with our hypothesis, wild-type cells are sensitive to DNA damage and HU when HUG1 is overexpressed. A Hug1 polyclonal antiserum reveals that HUG1 encodes a protein in budding yeast and its MEC1-dependent expression is delayed compared to the rapid induction of Rnr3p in response to HU treatment. Cell biology and subcellular fractionation experiments show localization of Hug1p-GFP to the cytoplasm upon HU treatment. The cytoplasmic localization of Hug1p-GFP is dependent on MEC1 pathway genes and coincides with the cytoplasmic localization of Rnr2p–Rnr4p. Taken together, the genetic interactions, gene expression, and localization studies support a novel role for Hug1p as a negative regulator of the MEC1 checkpoint response through its compartmentalization with Rnr2p–Rnr4p.

  12. Sediment transport investigations in Hugli estuary using radiotracer technique

    International Nuclear Information System (INIS)

    Sharma, V.K.; Pant, H.J.; Kulkarni, U.P.; Pendharkar, A.S.; Chakraborty, Kalyan; Mukhopadhyay, Suman; Chaudhuri, Bikas

    2006-01-01

    This paper describes sediment transport investigations carried out at two different locations in Hugli estuary along the shipping channel leading to Haldia Dock Complex of the Kolkata Port Trust, Kolkata. The objectives of these investigations were to evaluate the suitability of the proposed dumping sites for optimizing the dredging operation and implementing the recommendations of the River Regulatory Measures, Kolkata Port Trust, Kolkata

  13. Modiolus-Hugging Intracochlear Electrode Array with Shape Memory Alloy

    Directory of Open Access Journals (Sweden)

    Kyou Sik Min

    2013-01-01

    Full Text Available In the cochlear implant system, the distance between spiral ganglia and the electrodes within the volume of the scala tympani cavity significantly affects the efficiency of the electrical stimulation in terms of the threshold current level and spatial selectivity. Because the spiral ganglia are situated inside the modiolus, the central axis of the cochlea, it is desirable that the electrode array hugs the modiolus to minimize the distance between the electrodes and the ganglia. In the present study, we propose a shape-memory-alloy-(SMA- embedded intracochlear electrode which gives a straight electrode a curved modiolus-hugging shape using the restoration force of the SMA as triggered by resistive heating after insertion into the cochlea. An eight-channel ball-type electrode array is fabricated with an embedded titanium-nickel SMA backbone wire. It is demonstrated that the electrode array changes its shape in a transparent plastic human cochlear model. To verify the safe insertion of the electrode array into the human cochlea, the contact pressures during insertion at the electrode tip and the contact pressures over the electrode length after insertion were calculated using a 3D finite element analysis. The results indicate that the SMA-embedded electrode is functionally and mechanically feasible for clinical applications.

  14. EURANOS. The Handbook Users Group (HUG)

    DEFF Research Database (Denmark)

    Nisbet, A.F.; Andersson, Kasper Grann; Carlé, B.

    Three handbooks to assist in the management of contaminated food production systems, inhabited areas and drinking water supplies have been developed in conjunction with a wide range of stakeholders in Europe. These handbooks are living documents that will require updating from time to time.......eu-neris.net) to facilitate information exchange. Emergency centres in Member States not involved in the development of the handbooks were invited to take part in demonstration activities to establish whether the handbooks were useful for the purposes of contingency planning and accident management. Results from...... to remain state-of-the-art. To address this need, a handbook users’ group (HUG) was established in 2007 to provide a platform for maintaining the handbooks and to build a network of users for both the generic handbooks and any subsequently customised versions. A web site was set up (www...

  15. Molecular and biochemical characteristics of the inulosucrase HugO from Streptomyces viridochromogenes DSM40736 (Tü494)

    NARCIS (Netherlands)

    Frasch, Hans-Jörg; Leeuwen, Sander S van; Dijkhuizen, Lubbert

    2017-01-01

    Polyfructans are synthesized from sucrose by plants (mostly inulin) and by both Gram-negative and Gram-positive bacteria (mostly levan). In the phylum Actinobacteria only levan synthesis by Actinomyces species has been reported. We have identified a putative fructansucrase gene (hugO) in

  16. Impact of hydroxyurea on clinical events in the BABY HUG trial

    Science.gov (United States)

    Files, Beatrice A.; Luo, Zhaoyu; Miller, Scott T.; Kalpatthi, Ram; Iyer, Rathi; Seaman, Phillip; Lebensburger, Jeffrey; Alvarez, Ofelia; Thompson, Bruce; Ware, Russell E.; Wang, Winfred C.

    2012-01-01

    The Pediatric Hydroxyurea Phase 3 Clinical Trial (BABY HUG) was a phase 3 multicenter, randomized, double-blind, placebo-controlled clinical trial of hydroxyurea in infants (beginning at 9-18 months of age) with sickle cell anemia. An important secondary objective of this study was to compare clinical events between the hydroxyurea and placebo groups. One hundred and ninety-three subjects were randomized to hydroxyurea (20 mg/kg/d) or placebo; there were 374 patient-years of on-study observation. Hydroxyurea was associated with statistically significantly lower rates of initial and recurrent episodes of pain, dactylitis, acute chest syndrome, and hospitalization; even infants who were asymptomatic at enrollment had less dactylitis as well as fewer hospitalizations and transfusions if treated with hydroxyurea. Despite expected mild myelosuppression, hydroxyurea was not associated with an increased risk of bacteremia or serious infection. These data provide important safety and efficacy information for clinicians considering hydroxyurea therapy for very young children with sickle cell anemia. This clinical trial is registered with the National Institutes of Health (NCT00006400, www.clinicaltrials.gov). PMID:22915643

  17. DMPD: A role for caspases in the differentiation of erythroid cells and macrophages. [Dynamic Macrophage Pathway CSML Database

    Lifescience Database Archive (English)

    Full Text Available ges. Droin N, Cathelin S, Jacquel A, Guery L, Garrido C, Fontenay M, Hermine O,Solary E. Biochimie. 2008 Feb... Garrido C, Fontenay M, Hermine O,Solary E. Publication Biochimie. 2008 Feb;90(2):416-22. Epub 2007 Sep 2. P

  18. Transformation of Agricultural Land for Urbanisation, Infrastructural Development and Question of Future Food Security: Cases from Parts of Hugli District, West Bengal

    Directory of Open Access Journals (Sweden)

    Giyasuddin Siddique

    2017-11-01

    Full Text Available Developing countries of the world encounter urbanisation and infrastructural development in or around the fertile tracts and the absence of any landuse plan for desired land use change has led to conversion of farmlands, which is detrimental to future food security and environmental quality. Hugli district is traditionally well known as one of the most prosperous agricultural regions of West Bengal but the district is experiencing rapid urban extension and infrastructural development towards productive agricultural land since 1991. This has caused decline in the amount of agricultural production which may be treated as an indicator of increasing threat to the long run sustainable livelihood security of the people of the whole of West Bengal. This article critically explores the transformation of agricultural (farm land because of growing rate of urbanisation and infrastructural development, which in turn poses the question of threat to food (in security. Although, this is a growing problem across the universe, this article probes the future food security questions of Hugli district, West Bengal by examining the impact of the highly intertwined indicators of urbanisation and infrastructural development on agricultural (farm land use and its effect on food security. Regression analysis, Spearman’s Ranking Correlation Coefficient, Remote Sensing technologies, Markov Chain Model, Projection of future population growth and yield rate are employed to understand the depth of the problem. The result not only shows a direct negative correlation between urban extension and agricultural areal contraction but also the supervised classification of satellite imageries shows that there is rapid change of rural land use from 1996-2016. There is no match between future population growth and future yield rate of crops and the Markov Chain Model further predicts that the cropland will decrease from 62.77% to 42.90% and the built up area will increase from 31

  19. Rapid and sensitive detection of Plesiomonas shigelloides by loop-mediated isothermal amplification of the hugA gene.

    Directory of Open Access Journals (Sweden)

    Shuang Meng

    Full Text Available Plesiomonas shigelloides is one of the causative agents of human gastroenteritis, with increasing number of reports describing such infections in recent years. In this study, the hugA gene was chosen as the target to design loop-mediated isothermal amplification (LAMP assays for the rapid, specific, and sensitive detection of P. shigelloides. The performance of the assay with reference plasmids and spiked human stools as samples was evaluated and compared with those of quantitative PCR (qPCR. No false-positive results were observed for the 32 non-P. shigelloides strains used to evaluate assay specificity. The limit of detection for P. shigelloides was approximately 20 copies per reaction in reference plasmids and 5×10(3 CFU per gram in spiked human stool, which were more sensitive than the results of qPCR. When applied in human stool samples spiked with 2 low levels of P. shigelloides, the LAMP assays achieved accurate detection after 6-h enrichment. In conclusion, the LAMP assay developed in this study is a valuable method for rapid, cost-effective, and simple detection of P. shigelloides in basic clinical and field laboratories in the rural areas of China.

  20. 10 year Chernobyl Aid programmes of the Otto Hug Strahleninstitut-MHM: treatment and research projects on thyroid pathologies in republic of Belarus

    International Nuclear Information System (INIS)

    Lengfelder, E.; Frenzel, Ch.; Lengfelder, E.; Frenzel, Ch.; Demidchik, E.P.; Demidchik, J.E.; Sidorov, J.D.; Birukova, L.W.; Gamolina, L.I.; Prigoschaja, T.I.; Rabes, H.M.

    2003-01-01

    The unexpected serious increase in the incidence of thyroid cancer following the reactor accident in Chernobyl has led to considerable efforts from abroad to support Belarus in order to mitigate these heath problems. Otto Hug Radiation Institute started several long-term treatment and research projects on thyroid cancer and other diseases of this organ in 1991. Since 1993, the project 'Thyroid Centre Gomel has had more than 70,000 patients from this province for diagnosis and treatment of thyroid diseases including cancer. Starting in 1995 the project of the 'Histopathological Laboratory', is situated in the Oncological Dispensary in Minsk, where all children and juvenile and many adult thyroid cancers of Belarus are operated. More than 6,500 thyroid tumors were diagnosed with over 30,000 pathological slides preparing according to the internationally accepted standards. Additionally, this clinic has been supplied since 1997, so they can test for thyroid blood parameters. In 1997 the project of 'Radioiodine Therapy' started in Gomel, providing treatment for more than 450 patients since that time

  1. Uued loomad loomaaias - seekord pronksist / Maris Balbat

    Index Scriptorium Estoniae

    Balbat, Maris, 1936-

    2006-01-01

    Tallinna Loomaaias toimunud rahvusvahelise animalistliku skulptuuri festivalil saavutas I koha Hermine Kelleri "Šimpans", II koha Margarita Kamardina Moskvast ja Vitali Novikov Peterburist. Tauno Kangro "Siga" teenis ära publikupreemia

  2. Genetic determinism of oil acidity among some DELI oil palm ...

    African Journals Online (AJOL)

    Genetic determinism of oil acidity among some DELI oil palm (Elaeis guineensis Jacq.) progenies. Benoit Constant Likeng-Li-Ngue, Joseph Martin Bell, Georges Franck Ngando-Ebongue, Godswill Ntsefong Ntsomboh, Hermine Bille Ngalle ...

  3. Optimization of glucose oxidase production by Aspergillus niger

    African Journals Online (AJOL)

    user

    2011-02-28

    Feb 28, 2011 ... manganese, cobalt, thioglycolic acid, and gluconic acid according to (Liu et al., .... In this experiment duplicate media of glucose 10% were adjusted at different ... Glucose oxidase as a pharmaceutical anti oxidant Drug. Devt. ... Plush KS, Hellmuth K, Rinas U (1996). kinetics of glucose oxidase excretion by ...

  4. CERN signs with the Hôpitaux Universitaires de Genève

    CERN Multimedia

    2002-01-01

    Signature of the CERN-HUG agreements. From left to right: J. van der Boon, CERN Director of Administration, P. Pachoud (H.U.G.), M. Vieli (H.U.G.), A.-S. Cerne (CERN) and W. Kindl, Director of UNIQA Assurances S.A. On 4 July 2002, Mario Vieli, the Finance Director of the Hôpitaux Universitaires de Genève (H.U.G.), Pierre Pachoud, the vice-chairman of the H.U.G. Board of Directors and Anne-Sylvie Cerne, who is responsible for the Organization's health insurance contract, signed agreements on tariffs between the Organization and the Hôpitaux Universitaires de Genève. The main hospital of the H.U.G. group is the Cantonal Hospital. These agreements, approved by the Republic of Geneva's State Council last April, are the outcome of extensive negotiations. In fact, CERN is the first international organization to arrange for tariff agreements for the members of its Health Insurance Scheme (CHIS) with the H.U.G. directly. Moreover, these agreements are fully in line with CHIS's new tariff agreement policy, with ...

  5. Tallinna loomaaia Paldiski mnt. poolses nn. Põhjavärava lähistel...

    Index Scriptorium Estoniae

    2004-01-01

    IV Läänemeremaade animaskulptuurinäituse osavõtjate modelleerinud pronksist loomakujud pannakse 25. VIII loomaaeda hindamiseks välja. Žürii (loetletud) valikul osalevad festivali II voorus Sergejus Plotnikovas (Leedu), Margarita Kamardina, Vitali Novikov (Venemaa), Aleksander Litvinov, Rafael Danieljants (Eesti), Marylyn Gierow, Ann-Kristin Gustavsson, Hermine Keller (Rootsi), Peter Müller Larsen, Henrik Vilhelm Voldmester (Taani)

  6. Tracing partners of patients with syphilis infection remains challenging: experience of Geneva Hospital.

    Science.gov (United States)

    de Lorenzi, Caroline; Gayet-Ageron, Angèle; Girard-Strohbach, Martine; Toutous-Trellu, Laurence

    2017-10-01

    Syphilis has been reinstated on the list of notifiable diseases in Switzerland since 2006 and the active management of sexual partners is encouraged to avoid reinfection. However, contact tracing has yielded unsatisfactory results and the incidence of syphilis remains important, especially in high-risk populations. The aim of this study was to compare the proportions of notified sexual partners of patients diagnosed with syphilis by the laboratories of Geneva University Hospitals (HUG) with those diagnosed in private laboratories (non-HUG) and to assess the risk factors for no notification to sexual partners. All syphilis cases notified to the Office of the Surgeon General in Geneva (Switzerland) between 1 January 2011 and 31 December 2013 were analysed. The proportions of partner notification (PN) between HUG and non-HUG laboratories were compared by Chi square test and the main risk factors for no notification to sexual partners were assessed by binomial log-linear regression. Among a total of 720 notifications reported, 244 cases were diagnosed with contagious syphilis stages and 263 with non-contagious stages (i.e. successfully treated patients with or late latent cases). Overall, PN was higher among contagious than non-contagious cases (58.4% versus 31.0%; p = 0.030) and it was significantly higher in the non-HUG compared to the HUG group (75.9% versus 50.0%, respectively; p 45 years (RR 1.36; 95% CI: 1.05-1.76) and if the patient had received treatment for syphilis (RR 1.91; 95% CI: 1.38-2.66). Our results illustrate the difficulty of contact tracing in syphilis infection and the necessity to improve this crucial part of sexually transmitted infection management.

  7. 2143-IJBCS-Article-Dr Hermine Zime-Diawara

    African Journals Online (AJOL)

    hp

    Sur ces. 130 personnes, 108 ont suivi le traitement en intégralité et ont honoré rigoureusement les rendez-vous définis. Tous ces malades sont nés et vivent en zone d'endémie au Bénin. L'échantillon était constitué de 53,7% de femmes contre 46,3% d'hommes. Le sexe ratio de l'était donc de 1,16 en faveur des femmes.

  8. 1338-IJBCS-Article-Hermine 3eme Diawara+

    African Journals Online (AJOL)

    hp

    Artemisinin is extracted from the Asian plant Artemisia annua L. It has been proven to be, with its derivatives, the molecules that have shown so far the most powerful activity on malaria, even in its complicated forms and resistance cases. To resolve the problem of low aqueous solubility of this molecule, the use of.

  9. Conference for CERN Pensioners

    CERN Multimedia

    GS Department

    2010-01-01

    Wednesday, 19 January 2011, 2.30 to 4.30 p.m. Council Chamber, Main Building 503-1-001 RESEARCH PROJECT "Optimum brain ageing" ➢ “Intelligence and longevity” Dr François HERRMANN, University Hospitals of Geneva (HUG) ➢ “First results of the questionnaire: Promotion of Optimum Brain Ageing” Dr François HERRMANN, University Hospitals of Geneva (HUG) ➢\t➢\tDiscussion with the participants. In French Admission free

  10. Conference for CERN Pensioners

    CERN Multimedia

    GS Department

    2011-01-01

    Wednesday, 19 January 2011, 2.30 to 4.30 p.m. Council Chamber, Main Building 503-1-001 RESEARCH PROJECT "Optimum brain ageing" ➢ “Intelligence and longevity” Dr François HERRMANN, University Hospitals of Geneva (HUG) ➢ “First results of the questionnaire: Promotion of Optimum Brain Ageing” Dr François HERRMANN, University Hospitals of Geneva (HUG) ➢\t➢\tDiscussion with the participants. In French Admission free

  11. Body Image and Anti-Fat Attitudes: An Experimental Study Using a Haptic Virtual Reality Environment to Replicate Human Touch.

    Science.gov (United States)

    Tremblay, Line; Roy-Vaillancourt, Mélina; Chebbi, Brahim; Bouchard, Stéphane; Daoust, Michael; Dénommée, Jessica; Thorpe, Moriah

    2016-02-01

    It is well documented that anti-fat attitudes influence the interactions individuals have with overweight people. However, testing attitudes through self-report measures is challenging. In the present study, we explore the use of a haptic virtual reality environment to physically interact with overweight virtual human (VH). We verify the hypothesis that duration and strength of virtual touch vary according to the characteristics of VH in ways similar to those encountered from interaction with real people in anti-fat attitude studies. A group of 61 participants were randomly assigned to one of the experimental conditions involving giving a virtual hug to a female or a male VH of either normal or overweight. We found significant associations between body image satisfaction and anti-fat attitudes and sex differences on these measures. We also found a significant interaction effect of the sex of the participants, sex of the VH, and the body size of the VH. Female participants hugged longer the overweight female VH than overweight male VH. Male participants hugged longer the normal-weight VH than the overweight VH. We conclude that virtual touch is a promising method of measuring attitudes, emotion and social interactions.

  12. Jan Hoet : " Magritte ja Ensor - ühtaegu Valloonia ja Flandria keskpunkt" : Hermine Bokhorsti intervjuu Jan Hoetiga / Jan Hoet ; interv. Hermine Bokhorst, tõlk. Tamara Luuk

    Index Scriptorium Estoniae

    Hoet, Jan

    2002-01-01

    Tänapäevasest belgia kunstist, flaami ja vallooni kunstniku lähenemisviisidest, kunstnike toetamisest, Flandria ja frankofoonse Belgia muuseumipoliitika erinevusest, belglaste tundlikkusest kunsti suhtes jm.

  13. Dispersion processes in coastal waters - Some outstanding practical issues for monitoring and modelling

    Digital Repository Service at National Institute of Oceanography (India)

    Swamy, G.N.

    -induced diffusion, breaking of pollutant patch and its shore hugging, seasonal variabilities, physical limits of sampling, and concludes on remedial suggestions like examining problems of site specificity...

  14. Secondhand Smoke

    Science.gov (United States)

    ... clothing, when smokers come back inside, they should wash their hands and change their clothing, especially before holding or hugging children. Never smoke in a car with other people. Even exhaling out the window ...

  15. Planning for Pregnancy

    Science.gov (United States)

    ... Before Pregnancy Home Overview Planning for Pregnancy Women Men Image Library Women Who Want to Become Pregnant Women Who Do Not Want to Become Pregnant Hugging Nutrition Physical Activity Visiting the Doctor Planning for Pregnancy Language: English ( ...

  16. Altitude control in honeybees: joint vision-based learning and guidance.

    Science.gov (United States)

    Portelli, Geoffrey; Serres, Julien R; Ruffier, Franck

    2017-08-23

    Studies on insects' visual guidance systems have shed little light on how learning contributes to insects' altitude control system. In this study, honeybees were trained to fly along a double-roofed tunnel after entering it near either the ceiling or the floor of the tunnel. The honeybees trained to hug the ceiling therefore encountered a sudden change in the tunnel configuration midways: i.e. a "dorsal ditch". Thus, the trained honeybees met a sudden increase in the distance to the ceiling, corresponding to a sudden strong change in the visual cues available in their dorsal field of view. Honeybees reacted by rising quickly and hugging the new, higher ceiling, keeping a similar forward speed, distance to the ceiling and dorsal optic flow to those observed during the training step; whereas bees trained to follow the floor kept on following the floor regardless of the change in the ceiling height. When trained honeybees entered the tunnel via the other entry (the lower or upper entry) to that used during the training step, they quickly changed their altitude and hugged the surface they had previously learned to follow. These findings clearly show that trained honeybees control their altitude based on visual cues memorized during training. The memorized visual cues generated by the surfaces followed form a complex optic flow pattern: trained honeybees may attempt to match the visual cues they perceive with this memorized optic flow pattern by controlling their altitude.

  17. EUNUCHS IN THE BIBLE 1. INTRODUCTION

    African Journals Online (AJOL)

    plete discussion of the particular socio-cultural role played by eunuchs in antiquity, as ... is described by the words “he was in the house of the king”. The. Vulgate ... Mesopotamian countries (where human castration probably origi- nated; Hug ...

  18. The universe of conics from the ancient Greeks to 21st century developments

    CERN Document Server

    Glaeser, Georg; Odehnal, Boris

    2016-01-01

    This text presents the classical theory of conics in a modern form. It includes many novel results that are not easily accessible elsewhere. The approach combines synthetic and analytic methods to derive projective, affine and metrical properties, covering both Euclidean and non-Euclidean geometries. With more than two thousand years of history, conic sections play a fundamental role in numerous fields of mathematics and physics, with applications to mechanical engineering, architecture, astronomy, design and computer graphics. This text will be invaluable to undergraduate mathematics students, those in adjacent fields of study, and anyone with an interest in classical geometry. Augmented with more than three hundred fifty figures and photographs, this innovative text will enhance your understanding of projective geometry, linear algebra, mechanics, and differential geometry, with careful exposition and many illustrative exercises. Authors Hellmuth Stachel, born 1942, got his PhD and habilitation in geometry ...

  19. Hydroxyurea is associated with lower costs of care of young children with sickle cell anemia.

    Science.gov (United States)

    Wang, Winfred C; Oyeku, Suzette O; Luo, Zhaoyu; Boulet, Sheree L; Miller, Scott T; Casella, James F; Fish, Billie; Thompson, Bruce W; Grosse, Scott D

    2013-10-01

    In the BABY HUG trial, young children with sickle cell anemia randomized to receive hydroxyurea had fewer episodes of pain, hospitalization, and transfusions. With anticipated broader use of hydroxyurea in this population, we sought to estimate medical costs of care in treated versus untreated children. The BABY HUG database was used to compare inpatient events in subjects receiving hydroxyurea with those receiving placebo. Unit costs were estimated from the 2009 MarketScan Multi-state Medicaid Database for children with sickle cell disease, aged 1 to 3 years. Inpatient costs were based on length of hospital stay, modified by the occurrence of acute chest syndrome, splenic sequestration, or transfusion. Outpatient expenses were based on the schedule required for BABY HUG and a "standard" schedule for 1- to 3-year-olds with sickle cell anemia. There were 232 hospitalizations in the subjects receiving hydroxyurea and 324 in those on placebo; length of hospital stay was similar in the 2 groups. Estimated outpatient expenses were greater in those receiving hydroxyurea, but these were overshadowed by inpatient costs. The total estimated annual cost for those on hydroxyurea ($11 072) was 21% less than the cost of those on placebo ($13 962; P = .038). Savings on inpatient care resulted in a significantly lower overall estimated medical care cost for young children with sickle cell anemia who were receiving hydroxyurea compared with those receiving placebo. Because cost savings are likely to increase with age, these data provide additional support for broad use of hydroxyurea treatment in this population.

  20. 76 FR 8743 - Indian Health Professions Preparatory, Indian Health Professions Pre-Graduate and Indian Health...

    Science.gov (United States)

    2011-02-15

    ...: Montana, Mr. Delon Rock Above, Alternate: Ms. Wyoming. Bernice Hugs, IHS Area Scholarship Coordinator... Area Scholarship Mexico, Utah. Coordinator, Navajo Area IHS, P.O. Box 9020, Window Rock, AZ 86515, Tele... Area Scholarship Coordinator. Electronic applications are being accepted for this cycle. Go to http...

  1. Teaching Discriminated Social Approaches to Individuals with Angelman Syndrome

    Science.gov (United States)

    Fichtner, Caitlin S.; Tiger, Jeffrey H.

    2015-01-01

    Angelman syndrome is a neurogenetic disorder characterized by intellectual and developmental disability. Common behavioral characteristics of this disorder include a heightened interest in social interactions and frequent bids to initiate interaction. These bids can be problematic, for instance, when a child attempts to hug strangers in public…

  2. An Analysis of Military Use of Commercial Satellite Communications

    Science.gov (United States)

    2008-09-01

    frequent visits to my office (complete with hugs, throwing of stuffed animals, and random strumming of my guitar ) helped to ensure the maintenance of...policy). This option is the primary recommendation of this thesis, although the Depot 50/50 Paradigm also scored relatively high. The following

  3. COMMUNITY MEDICINE & PRIMARY HEALTH CARE

    African Journals Online (AJOL)

    ajiboro

    these lines: eating together 261/669 (39%), hugging 149/668 (22%), shaking ... Level of education was associated with positive attitudes towards ocular .... the about 250 ethnic groups of Nigeria. ..... ocular cancer are reflection of challenges ... Care: Focus Groups with Older African ... youths in a Nigerian local population.

  4. Feeding experience and relative size modify the begging strategies of nestlings

    NARCIS (Netherlands)

    Rodriguez-Girones, MA; Zuniga, JM; Redondo, T

    2002-01-01

    The offspring of birds and mammals use a combination of movements and vocalizations, known as hugging, to solicit food from their parents. A widespread interpretation of begging is that it constitutes air honest signal of offspring need. But we know that in the house sparrow (Passer domesticus) the

  5. S Pancharatnam (1934–1969): Three Phases

    Indian Academy of Sciences (India)

    IAS Admin

    stood near Panchan for sometime and then hugged him! – Kausalya ... It was quite an unusual experience on the first day to start it with a prayer ... He was a young man—only 35 years old—when he died in Oxford on 28 May 1969. At that time.

  6. [Ophthalmologists in the proximity of Adolf Hitler].

    Science.gov (United States)

    Rohrbach, J M

    2012-10-01

    Adolf Hitler met or at least knew about 5 ophthalmologists. The chair of ophthalmology in Berlin, Walther Löhlein, personally examined Hitler's eyes at least two times. The chair of ophthalmology in Breslau, Walter Dieter, developed "air raid protection spectacles" with the aid of high representatives of the NS-system and probably Adolf Hitler himself. Heinrich Wilhelm Kranz became rector of the universities of Giessen and Frankfurt/Main. He was known as a very strict advocate of the NS-race hygiene. Werner Zabel made plans for Hitler's diet and tried to interfere with Hitler's medical treatment. Finally, Hellmuth Unger was an influential representative of the medical press and a famous writer. Three of his novels with medical topics were made into a film which Hitler probably saw. Hitler had, so to say, a small "ophthalmological proximity" which, however, did not play a significant role for himself or the NS-state. © Georg Thieme Verlag KG Stuttgart · New York.

  7. A New Type of Great Power Relationship Between the United States and China: The Military Dimension

    Science.gov (United States)

    2014-09-01

    multipolar world system and a pro- spective security and economic partner of the United States. This stands midway between the panda -hug- ging and dragon...spending, on the other hand, are more difficult to calculate and may prove significantly less easy to bear . 79. Eberhard Sandschneider, “Is China’s

  8. Family arizing

    NARCIS (Netherlands)

    Croes, M.J.G.; Feijs, L.M.G.; Chen, L.; Djajadingrat, T.; Feijs, L.M.G.; Hu, J.; Kufin, S.H.M.; Rampino, L.; Rodriguez, E.; Steffen, D.

    2015-01-01

    In this demo we show the two main components of the Family Arizing system which allows parents to stay in contact with their child and, in cases of distress, provide the child with a remote comforting hug. The two components to be shown are the active necklace and the active snuggle.

  9. Too Much Stuff Can Hinder Children: What Do Children Really Want from Us?

    Science.gov (United States)

    Arnold, Johann Christoph

    2002-01-01

    Contends that our materialistic culture has drawn in families and created pampered, spoiled, and unhappy children which parents, child care providers, and educators are left to deal with. Asserts that parents should not be tempted by "things" to make their children happy; rather they should provide time, attentiveness, hugs, and an…

  10. Teaching a Child with Autism and Severe Language Delays to Reject: Direct and Indirect Effects of Functional Communication Training

    Science.gov (United States)

    Martin, Christian A.; Drasgow, Erik; Halle, James W.; Brucker, Jennifer M.

    2005-01-01

    We used functional communication training to teach Bob, a 10-year-old student with autism and severe language delays, to reject items by touching an icon. Our initial assessment revealed that Bob's behaviours serving a rejecting function consisted of pushing away, yelling, bear hugging-grabbing, and leaving. We used prompting, differential…

  11. Defense Management: U.S. Southern Command Demonstrates Interagency Collaboration, but Its Haiti Disaster Response Revealed Challenges Conducting a Large Military Operation

    Science.gov (United States)

    2010-07-01

    Barbados, Belize, Bolivia, Brazil, Chile , Colombia, Costa Rica, Dominican Republic, Ecuador, El Salvador, Guatemala, Guyana, Haiti, Honduras, Jamaica...19The international liaisons at SOUTHCOM include representatives from eight countries— Argentina, Brazil, Canada, Chile ...Nongovernmental Participants Agua Viva Alliance for Rabies Control FACE Food for the Poor Haiti Resource Development Foundation Hugs Across America

  12. Creating a Successful Academic Climate for Urban Students

    Science.gov (United States)

    Slaughter, Terri

    2009-01-01

    Teaching students in the inner city has been likened to hugging a porcupine--teachers nudge them toward success while getting pricked along the way. Many urban students perform below proficiency level and are difficult to manage. Their apathy toward completing class assignments, let alone homework, compounds the problem. As a whole, educators do…

  13. Aunque cerca...sano: Una guia para prevencion de los riesgos de los pesticidas (Although Nearby...Healthy: A Guide for the Prevention of Pesticide Risks).

    Science.gov (United States)

    Saenz, Salvador

    Intended for Spanish-speaking farmworkers with children, this publication in comic book format tells these parents how they can protect their children from pesticide risks. On returning home from work, one farmworker couple does not hug their young children. When their behavior is questioned by neighbors, the mother explains that the fields were…

  14. A "migrant friendly hospital" initiative in Geneva, Switzerland: evaluation of the effects on staff knowledge and practices.

    Science.gov (United States)

    Hudelson, Patricia; Dominice Dao, Melissa; Perneger, Thomas; Durieux-Paillard, Sophie

    2014-01-01

    International migration poses important challenges to European health care systems. The development of "migrant friendly hospitals" has been identified as a priority in both Europe and Switzerland. A multi-pronged initiative was developed at Geneva University Hospitals (HUG) to improve staff knowledge and use of existing "migrant friendly" resources. A self-administered questionnaire was sent pre and post-intervention to random samples of 4 major professional groups with direct patient contact at the HUG. The questionnaire assessed staff knowledge, attitudes and reported practices regarding the care of migrant patients. Overall response rate was 51% (N = 1460) in 2010 but only 19% (N = 761) in 2013 owing to an institutionally imposed change in survey method. Despite these difficulties, and after adjusting for sample differences, we found that respondents in 2013 were significantly more likely to have received training in how to organize an appointment with an interpreter, how to work with an interpreter and about health and social services available for migrant patients. Respondents were also significantly more likely to have used several Migrant Friendly structures at the HUG. Use of, preference for and perceived skill at working with professional interpreters all improved, and respondents were both more likely to be encouraged by their supervisors to use professional interpreters, and less likely to be encouraged to look for alternative solutions for communicating with non francophone patients. Finally, 2013 respondents encountered fewer difficulties caring for migrant patients, although lack of time and language barriers continued to be the most important sources of difficulty. Our results suggest that an institution-wide information campaign may contribute to increased awareness and use of migrant friendly resources by clinical staff. Hospital commitment and financing, along with inter-departmental participation in all activities were important in creating and

  15. A "migrant friendly hospital" initiative in Geneva, Switzerland: evaluation of the effects on staff knowledge and practices.

    Directory of Open Access Journals (Sweden)

    Patricia Hudelson

    Full Text Available BACKGROUND: International migration poses important challenges to European health care systems. The development of "migrant friendly hospitals" has been identified as a priority in both Europe and Switzerland. METHODS: A multi-pronged initiative was developed at Geneva University Hospitals (HUG to improve staff knowledge and use of existing "migrant friendly" resources. A self-administered questionnaire was sent pre and post-intervention to random samples of 4 major professional groups with direct patient contact at the HUG. The questionnaire assessed staff knowledge, attitudes and reported practices regarding the care of migrant patients. RESULTS: Overall response rate was 51% (N = 1460 in 2010 but only 19% (N = 761 in 2013 owing to an institutionally imposed change in survey method. Despite these difficulties, and after adjusting for sample differences, we found that respondents in 2013 were significantly more likely to have received training in how to organize an appointment with an interpreter, how to work with an interpreter and about health and social services available for migrant patients. Respondents were also significantly more likely to have used several Migrant Friendly structures at the HUG. Use of, preference for and perceived skill at working with professional interpreters all improved, and respondents were both more likely to be encouraged by their supervisors to use professional interpreters, and less likely to be encouraged to look for alternative solutions for communicating with non francophone patients. Finally, 2013 respondents encountered fewer difficulties caring for migrant patients, although lack of time and language barriers continued to be the most important sources of difficulty. CONCLUSION: Our results suggest that an institution-wide information campaign may contribute to increased awareness and use of migrant friendly resources by clinical staff. Hospital commitment and financing, along with inter

  16. Investigation of Gallium Nitride Transistor Reliability through Accelerated Life Testing and Modeling

    Science.gov (United States)

    2011-12-01

    than my parents or I did, and recommended to my mother that I be advanced from his math class. I am grateful to my paternal grandmother who...without her. I thank her for her patience with me. My children are an inspiration to me. I thank them for their hugs, kisses , and sweet prayers

  17. Fantasy and Experiential-Gestalt Therapy.

    Science.gov (United States)

    Witchel, Robert

    Fantasy activities are part of everyday experience. The author imagines hugging or touching someone, daydreams about sitting on a bench or riverbank, visualizes standing up during a boring meeting and shouting "let's wake up and do something!" Fantasy is also a tool that can be used in experimenting with new behavior, becoming more aware…

  18. The Feminine Divine, the Hug And Feminine Hindu Spiritual ...

    African Journals Online (AJOL)

    In their recent article, Sharma and Jain (2013) make the point that leadership and management are twinned, complementary and inextricably linked, or as they put it, “Go hand in hand”. They go a step further though and draw from Warren Bennis' list of the differences between 'the leader' and 'the manager' and state that ...

  19. Measurement of fast assembly spectra using time-of-flight method

    International Nuclear Information System (INIS)

    Duquesne, Henry; Rotival, Michel; Schmitt, Andre; Allard, Christian; De Keyser, Albert; Hortsmann, Henri

    1975-07-01

    Measurement of neutron spectra made in fast subcritical assemblies HUG 3 and PHUG 3 (uranium-graphite and plutonium-graphite) utilizing time-of-flight techniques are described. The matrix were excited by the pulsed neutron source from the BCMN Linac beam impinging on a target of natural uranium. Details of the experimental procedure, safety studies, detector calibration and data reduction are given [fr

  20. Women of Gustav Klimt doi:10.5007/1807-1384.2010v7n2p107

    Directory of Open Access Journals (Sweden)

    José Artur Molina

    2010-07-01

    Full Text Available Study the production of Gustav Klimt is browsing through the history of a country, Austria, and travel the world of the Austro-Hungarian in their bellies. This work attempts to reflect the rebelliousness of the women who do not want to be sentenced to confinement despotic promoted by a man's world. Klimt, by passion, hugs, with odd aesthetic, this flag.

  1. Reading and listening in people with aphasia: effects of syntactic complexity.

    Science.gov (United States)

    DeDe, Gayle

    2013-11-01

    The purpose of this study was to compare online effects of syntactic complexity in written and spoken sentence comprehension in people with aphasia (PWA) and adults with no brain damage (NBD). The participants in Experiment 1 were NBD older and younger adults (n = 20 per group). The participants in Experiment 2 were 10 PWA. In both experiments, the participants read and listened to sentences in self-paced reading and listening tasks. The experimental materials consisted of object cleft sentences (e.g., It was the girl who the boy hugged.) and subject cleft sentences (e.g., It was the boy who hugged the girl.). The predicted effects of syntactic complexity were observed in both Experiments 1 and 2: Reading and listening times were longer for the verb in sentences with object compared to subject relative clauses. The NBD controls showed exaggerated effects of syntactic complexity in reading compared to listening. The PWA did not show different modality effects from the NBD participants. Although effects of syntactic complexity were somewhat exaggerated in reading compared with listening, both the PWA and the NBD controls showed similar effects in both modalities.

  2. First-generation Korean-American parents' perceptions of discipline.

    Science.gov (United States)

    Kim, Eunjung; Hong, Seunghye

    2007-01-01

    Nurses not only need to be familiar with professional guidelines of discipline and but also need to be aware of variances in styles of acceptable discipline across cultural groups. The goal of this study was to explore cultural influences in relation to (1) first-generation Korean-American parents' perceptions of common discipline strategies in the United States, and (2) discipline strategies commonly used among first-generation Korean-American parents. Inductive content analysis was used to analyze interview data from seven first-generation Korean-American parents. Derived themes indicated that parents considered spanking/hitting and less hugging/kissing as Korean style, and time-out, use of sticker charts, hugging/kissing, removing/adding privileges, and giving chores as American style. Recent immigrant parents were not familiar with common positive discipline strategies in the United States. As they adapted to mainstream society, they discontinued what they perceived to be negative aspects of Korean style and adopted positive aspects of American style. They were sensitive to children's views on discipline, and they experienced communication difficulties with children. These findings indicated that Korean-American parents' perceptions of discipline strategies were shaped by living in two cultures and were different from western viewpoints.

  3. Investigating Thematic Roles through Implicit Learning: Evidence from Light Verb Constructions

    Directory of Open Access Journals (Sweden)

    Eva Wittenberg

    2017-06-01

    Full Text Available The syntactic structure of a sentence is usually a strong predictor of its meaning: Each argument noun phrase (i.e., Subject and Object should map onto exactly one thematic role (i.e., Agent and Patient, respectively. Some constructions, however, are exceptions to this pattern. This paper investigates how the syntactic structure of an utterance contributes to its construal, using ditransitive English light verb constructions, such as “Nils gave a hug to his brother,” as an example of such mismatches: Hugging is a two-role event, but the ditransitive syntactic structure suggests a three-role event. Data from an eye-tracking experiment and behavioral categorization data reveal that listeners learn to categorize sentences according to the number of thematic roles they convey, independent of their syntax. Light verb constructions, however, seem to form a category of their own, in which the syntactic structure leads listeners down an initial incorrect assignment of thematic roles, from which they only partly recover. These results suggest an automatic influence of syntactic argument structure on semantic interpretation and event construal, even in highly frequent constructions.

  4. Digitisation of the CERN Audio Archives

    CERN Multimedia

    Maximilien Brice

    2006-01-01

    Since the creation of CERN in 1954 until mid 1980s, the audiovisual service has recorded hundreds of hours of moments of life at CERN on audio tapes. These moments range from inaugurations of new facilities to VIP speeches and general interest cultural seminars The preservation process started in June 2005 On these pictures, we see Waltraud Hug working on an open-reel tape.

  5. The Panda Bear logo as crowbar. World Wildlife Fund approach useful for many countries

    Energy Technology Data Exchange (ETDEWEB)

    Quarles van Ufford, A.; Van der Weijden, E. [World Wildlife Fund WWF, Zeist (Netherlands)

    2001-07-01

    WWF in the Netherlands has taken the initiative to build extremely energy efficient houses without pushing up the costs or needing subsidies. By utilizing their public relations experience, and by introducing the famous panda bear logo the programme has become a hug success. This approach could also be copied in other countries. The process and the results of the project are described and could act as a guide for local initiatives.

  6. Measurement and analysis of self-noise in hybrid-driven underwater gliders

    Directory of Open Access Journals (Sweden)

    LIU Lu

    2017-08-01

    Full Text Available The Hybrid-driven Underwater Glider (HUG is a new type of submersible vehicle which combines the functions of traditional Autonomous Underwater Vehicles(AUVand Autonomous Underwater Gliders(AUG. In order to study its noise source distribution and basic self-noise characteristics, a self-noise acquisition system based on the HUG was designed and developed, and a noise analysis test carried out in a free-field pool. In August 2016, the sea trial of the Petrel II glider was conducted in the South China Sea, with observation data at a depth range of 1 000 m as the research object. The self-noise data of the glider platform under different working conditions was obtained through the step-by-step operation method. The experimental analysis and results show that the self-noise acquisition system is stable. The contribution of mechanical noise to self-noise is greatest when the glider works in the gliding mode, while the self-noise band above 500 Hz is closely related to the work of the buoyancy adjustment unit, and peaks at 1 kHz. According to the analysis of the basic characteristics of self-noise, this provides some guidance for the implementation of vibration and noise reduction.

  7. Two Steps Forward, One Step Back: Why the New UCMJ Rape Law Missed the Mark, and How an Affirmative Consent Statute Will Put it Back on Target

    Science.gov (United States)

    2007-04-01

    they had been sexually assaulted, and the administration had failed to investigate the reported crimes. See Cathy Booth - Thomas/Tucson, The Air...victim gave conflicting accounts of their relationship. The victim said that M.T.S. had tried to kiss her several times and once attempted to put...106 Id 107 Id. at 1268. 108 Id. 109 Id 110 Id 21 Their relationship had led to kissing and hugging and they had discussed having sexual

  8. Efficacy of Laser Fluorescence in Dental Caries Diagnosis: A Meta-Analysis

    Science.gov (United States)

    2012-06-01

    detecting secondary caries around amalgam restorations. Diniz and colleagues (53) examined the influence of clear and opaque sealants on laser...Int Dent J 1997; 47(5): 259-265. 36. De Paula A, Campos J, Diniz M, Hebling J, Rodrigues J. In situ and in vitro comparison of laser fluorescence...DIAGNOdent in the detection of secondary carious lesions. Acta Odont Scandinavia, 2005; 63: 26-30. 53. Diniz M, Rodrigues J, Hug I, Cordeiro R, Lussi

  9. The Role of Isolation in Radicalization: How Important Is It?

    Science.gov (United States)

    2013-12-01

    Hug 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Naval Postgraduate School Monterey, CA 93943-5000 8. PERFORMING ORGANIZATION REPORT...bully. The bully punched Timothy, and he fled and wept in the car.133 He felt like a failure to his father, who was an accomplished softball player...psychologists who performed interviews with Breivik. His lack of connection with his parents can also be seen in his compendium in he writes extensively

  10. Indian Defense Procurements: Advantage Russia or USA?

    Science.gov (United States)

    2015-02-17

    premiers of both the countries. The recent visit of President Obama saw Mr. Modi breaking the protocol to greet him with a bear hug on his arrival at New...between Russia and US. 56 Ritesh Srivastava, India caught between Russia and US. 57 Ankit Panda , “Pakistan Courts Both US and Russia on Defense...www.indiatvnews.com/business/india/-india-invites-japan-to-join-rs-50000-crore- submarine-project-17058.html (accessed 3 February 2015). Panda , Ankit. “Pakistan

  11. Delineating the relationship between chromophoric dissolved organic matter (CDOM) variability and biogeochemical parameters in a shallow continental shelf

    OpenAIRE

    Sourav Das; Sugata Hazra; Aneesh A. Lotlikar; Isha Das; Sandip Giri; Abhra Chanda; Anirban Akhand; Sourav Maity; T. Srinivasa Kumar

    2016-01-01

    Absorption coefficient of chromophoric dissolved organic matter (CDOM) at 440 nm [aCDOM (440)], sea surface salinity (SSS), total suspended matter (TSM) and chlorophyll-a (chl-a) were measured during October, 2014 to March, 2015 in the shallow continental shelf waters of the Hugli Estuary, adjacent to West Bengal coast, India. The primary objective of the study was to characterize the relationship between aCDOM (440) and the above mentioned biogeochemical parameters. Upon analyzing the result...

  12. New offer for our members

    CERN Document Server

    Staff Association

    2014-01-01

    Allianz Switzerland: Simply at your service Protect yourself, your family, and your legacy! With Jacques and Mathias Hug on your side representing Allianz Switzerland, you benefit from 40 years of experience in Swiss insurance, retirement planning, and tax and real estate optimisation. We are here to answer any and all questions you might have in French, English, German, Spanish, and Italian. Up to 25% discount on insurance solutions in Switzerland www.jhugetfils.com - acern@allianz.ch

  13. Wooing the Dark Continent: U.S. and China Engagement Strategy in Africa, is it Complimentary or Competition

    Science.gov (United States)

    2008-05-01

    put it directly in conflict with Tokyo in the South China Sea . China has been successful in using its “soft power” to reduce the leverage of the West...59Ibid., 20. 60Gill and Reilly, 43. 30 The Two China’s as well as the Mutually Parasitic Economies (US/China...environment for all parties involved. African Perspectives “Panda Hug or Dragon Bite?” “Until the lion has his or her own storyteller, the hunter will

  14. A Revolution in Information Technology - Cloud Computing

    OpenAIRE

    Divya BHATT

    2012-01-01

    What is the Internet? It is collection of “interconnected networks” represented as a Cloud in network diagrams and Cloud Computing is a metaphor for certain parts of the Internet. The IT enterprises and individuals are searching for a way to reduce the cost of computation, storage and communication. Cloud Computing is an Internet-based technology providing “On-Demand” solutions for addressing these scenarios that should be flexible enough for adaptation and responsive to requirements. The hug...

  15. Tree-hugging koalas demonstrate a novel thermoregulatory mechanism for arboreal mammals.

    Science.gov (United States)

    Briscoe, Natalie J; Handasyde, Kathrine A; Griffiths, Stephen R; Porter, Warren P; Krockenberger, Andrew; Kearney, Michael R

    2014-06-01

    How climate impacts organisms depends not only on their physiology, but also whether they can buffer themselves against climate variability via their behaviour. One of the way species can withstand hot temperatures is by seeking out cool microclimates, but only if their habitat provides such refugia. Here, we describe a novel thermoregulatory strategy in an arboreal mammal, the koala Phascolarctos cinereus. During hot weather, koalas enhanced conductive heat loss by seeking out and resting against tree trunks that were substantially cooler than ambient air temperature. Using a biophysical model of heat exchange, we show that this behaviour greatly reduces the amount of heat that must be lost via evaporative cooling, potentially increasing koala survival during extreme heat events. While it has long been known that internal temperatures of trees differ from ambient air temperatures, the relevance of this for arboreal and semi-arboreal mammals has not previously been explored. Our results highlight the important role of tree trunks as aboveground 'heat sinks', providing cool local microenvironments not only for koalas, but also for all tree-dwelling species. © 2014 The Author(s) Published by the Royal Society. All rights reserved.

  16. Tree-hugging koalas demonstrate a novel thermoregulatory mechanism for arboreal mammals

    Science.gov (United States)

    Briscoe, Natalie J.; Handasyde, Kathrine A.; Griffiths, Stephen R.; Porter, Warren P.; Krockenberger, Andrew; Kearney, Michael R.

    2014-01-01

    How climate impacts organisms depends not only on their physiology, but also whether they can buffer themselves against climate variability via their behaviour. One of the way species can withstand hot temperatures is by seeking out cool microclimates, but only if their habitat provides such refugia. Here, we describe a novel thermoregulatory strategy in an arboreal mammal, the koala Phascolarctos cinereus. During hot weather, koalas enhanced conductive heat loss by seeking out and resting against tree trunks that were substantially cooler than ambient air temperature. Using a biophysical model of heat exchange, we show that this behaviour greatly reduces the amount of heat that must be lost via evaporative cooling, potentially increasing koala survival during extreme heat events. While it has long been known that internal temperatures of trees differ from ambient air temperatures, the relevance of this for arboreal and semi-arboreal mammals has not previously been explored. Our results highlight the important role of tree trunks as aboveground ‘heat sinks’, providing cool local microenvironments not only for koalas, but also for all tree-dwelling species. PMID:24899683

  17. The Hugging Team: The Role of Technology in Business Networking Practices

    DEFF Research Database (Denmark)

    Thorsø Sørensen, Anne; Shklovski, Irina

    2011-01-01

    Technological devices for social networking are produced in droves and networking through media seems to be the way of getting ahead in business. We examine what role technology plays in the creation, development and maintenance of business relationships among entrepreneurs in Copenhagen. We find...... that mediated communication is useful in all stages of relational maintenance but only in a supportive role in relational development where co-presence and shared personal experiences take center-stage, generating trust necessary for business relationships to work. These trust-developing experiences take effort...

  18. Sexism in Language: Do Fiction Writers Assign Agentive and Patient Roles Equally to Male and Female Characters?

    Directory of Open Access Journals (Sweden)

    Dunlop Ochieng

    2012-10-01

    Full Text Available Problem Statement: Studies have shown that language is used discriminatorily to women and men. Hence, there have been movements against gender biased language−the movements which are reported so successful especially in the West.Purpose of Study: This paper however argues that discrimination stems from speakers’ minds; and hence performing gender neutral language alone does not confirm gender neutrality of the performer. The reliable way of judging gender neutrality would then be studying the speakers’ minds.Method: The study applied psychoanalytic literary criticism as a gateway to the unconscious minds of American authors–to find out how gender neutral they were at cognitive level. Through psychoanalytic literary criticism, authors’ suppressed desires would find their way out onto their works in a distorted form. Along these lines, the study assessed the equality in assigning agentive and patient semantic roles between males and females in American fictions–to find out who between males and females were frequently assigned agentive and patient roles of the reciprocal verbs: kiss, hug, marry, and divorce.Findings: The study found out that males were assigned more agentive roles in kiss and hug, and females in divorce. Moreover, both were assigned almost equal roles in marry.Conclusion: The implication of the findings is that speakers’ unconscious mind is basically gender biased along gender stereotypes.

  19. HIV/AIDS transmission knowledge among adolescents aged 11 years from Southern Brazil.

    Science.gov (United States)

    Gonçalves, Helen; González-Chica, David Alejandro; Menezes, Ana M B; Hallal, Pedro C; Araújo, Cora L P; Dumith, Samuel C

    2013-06-01

    To investigate the effect of demographic, socioeconomic, educational and family variables on HIV/AIDS knowledge among adolescents aged 11 years. 3,949 adolescents born in Pelotas (Brazil). HIV/AIDS knowledge was assessed through a self-administered questionnaire and measured through five questions about HIV transmission: heterosexual intercourse, homosexual intercourse, needle sharing, open-mouth kissing and hugging someone with AIDS. All the analyses were adjusted based on a hierarchical model, using Poisson regression with robust adjustment of variance. Prevalence of wrong answers to the examined questions were 17.2% for heterosexual transmission, 44.1% for homosexual intercourse, 34.9% for needle sharing, 25.6% for kiss on the mouth and 16.2% for hugging someone with AIDS. In adjusted analysis, lower knowledge levels were more prevalent among boys, adolescents with lower socioeconomic status and with less maternal education level, among those who had not talked about sex with mother and without sexual education lessons at school. Knowledge was not associated with school type (public or private), skin color or talk about sex with father. Providing information to adolescents is essential to improve knowledge about HIV and other sexually transmitted infections, especially among young males, with lower socioeconomic status and with lower maternal education level. Public policies aimed to reducing HIV infection should consider maternal and school relevance to improve knowledge on adolescents.

  20. Enhancing Mediated Interpersonal Communication through Affective Haptics

    Science.gov (United States)

    Tsetserukou, Dzmitry; Neviarouskaya, Alena; Prendinger, Helmut; Kawakami, Naoki; Ishizuka, Mitsuru; Tachi, Susumu

    Driven by the motivation to enhance emotionally immersive experience of real-time messaging in 3D virtual world Second Life, we are proposing a conceptually novel approach to reinforcing (intensifying) own feelings and reproducing (simulating) the emotions felt by the partner through specially designed system, iFeel_IM!. In the paper we are describing the development of novel haptic devices (HaptiHeart, HaptiHug, HaptiTickler, HaptiCooler, and HaptiWarmer) integrated into iFeel_IM! system, which architecture is presented in detail.

  1. Winter Frost and Fog

    Science.gov (United States)

    2005-01-01

    This somewhat oblique blue wide angle Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) image shows the 174 km (108 mi) diameter crater, Terby, and its vicinity in December 2004. Located north of Hellas, this region can be covered with seasonal frost and ground-hugging fog, even in the afternoon, despite being north of 30oS. The subtle, wavy pattern is a manifestation of fog. Location near: 28oS, 286oW Illumination from: upper left Season: Southern Winter

  2. Kunst, Klima og Kritik

    OpenAIRE

    Mikkelsen, Kasper Bendix; Sparrebro, Aske Tim; Højersgaard, Jeppe Højbjerg; Foss, Uffe Michael Rask; Lund, Emilie Charlotte Walsøe

    2017-01-01

    AbstractThis study investigates the relationship between the Romantic trope of Nature and the environmental crisis in modern film and literature. It argues that the continued circulation of this Romantic trope and view of Nature in art contributes to passivity in regards to otherwise acute problems concerning climate change. Danish Romantic poet Adam Oehlenschläger is used to explain and exemplify the birth and use of the original Nature-trope in its purest form whilst an analysis Pixar’s hug...

  3. Rapid Optical Detection and Classification of Microbes in Suspicious Powders

    Science.gov (United States)

    2018-06-01

    Asher, “A New 224nm Hollow Cathode UV Laser Raman Spectrometer”, J. App. Spectroscopy, Vol. 55, No. 1, Jan 2001. [5] Storrie-Lombardi, M. C., W. F...Bhartia,R., E.C. Salas, W.F. Hug, R.D. Reid, A.L. Lane, K.J. Edwards, and K.J. Nealson, “Label-free bacterial imaging with deep UV laser induced...on natural surfaces using solar-blind deep UV excitation and detection. Detection is typically accomplished in less one second. The detection method

  4. Muddy waters

    Digital Repository Service at National Institute of Oceanography (India)

    DineshKumar, P.K.

    and represent a unique oceanographic phenomenon. They are tranquil marine areas hugging the coast, which develop during the roughest monsoon period. They have a special feature of dampening high waves due to the huge quantities of mud in suspension close... the sky for the onset of the monsoon rains. When strong winds and high waves make it impossible to go out into the sea, the entire fisherfolk pray for the appearance of mud banks. The southwest monsoon arrives in Kerala with all its fury by early...

  5. People and things. CERN Courier, Oct 1991, v. 31(8)

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1991-10-15

    The article reports on achievements of various people, staff changes and position opportunities within the CERN organization and contains news updates on upcoming or past events: ; Hampton University Graduate Studies (HUGS) at CEBAF, a summer program in electromagnetic nuclear physics held at the Continuous Electron Beam Accelerator Facility, Newport News, Virginia, has completed its sixth year. ; With research and development work pushing ahead for the experimental programme at the proposed LHC proton collider in CERN's LEP tunnel, attention is also turning to preparations for the experiments themselves.

  6. Sensitivity of physical examination versus arthroscopy in diagnosing subscapularis tendon injury.

    Science.gov (United States)

    Faruqui, Sami; Wijdicks, Coen; Foad, Abdullah

    2014-01-01

    The purpose of this study was to examine the accuracy of physical examination in the detection of subscapularis tendon tears and compare it with the gold standard of arthroscopy to determine whether clinical examination can reliably predict the presence of subscapularis tendon tears. This was a retrospective analysis of 52 patients (52 shoulders) who underwent arthroscopic subscapularis tendon repairs between September 2008 and April 2012. Positive findings on any combination of the belly press, lift-off, and bear hug tests constituted a positive physical examination result. There was a positive finding on physical examination in 42 of 52 patients. The sensitivity of the physical examination as a whole was 81%. The literature has shown that the belly press, bear hug, and lift-off tests are specific to the subscapularis tendon. To the authors’ knowledge, this is the first study to evaluate the sensitivity of these 3 separate clinical tests as a composite. Knowledge regarding the sensitivity of the subscapularis-specific physical examination as a composite can lead practitioners to implement all 3 components, even when 1 test has a negative finding, thus promoting a more thorough physical examination. Because unrepaired subscapularis tendon tears can result in poor outcomes in the repair of other rotator cuff tendons, a complete physical examination would be beneficial to patients with shoulder pathology. The authors conclude that physical examination, when performed consistently by an experienced practitioner, can reliably predict the presence of subscapularis tendon tears.

  7. Sexual behaviors among older adults in Spain: results from a population-based national sexual health survey.

    Science.gov (United States)

    Palacios-Ceña, Domingo; Carrasco-Garrido, Pilar; Hernández-Barrera, Valentín; Alonso-Blanco, Cristina; Jiménez-García, Rodrigo; Fernández-de-las-Peñas, César

    2012-01-01

    The Spanish National Sexual Health Survey (SNSHS) is designed to examine sexual activity, sexual behaviors, and sexual health among the Spanish population. To describe sexual activity and behaviors of Spaniards aged ≥ 65 years old focusing on gender differences. A population-based descriptive study was conducted using individual data from the SNSHS. The number of subjects aged ≥ 65 years included was 1,939 (1,118 women, 821 men). Sexual activity, frequency, sexual behaviors, sexual practices, and reasons for lack of sexual activity were assessed from questions included in the survey. Subjects who reported having any sexual practice including giving or receiving kissing and hugging, vaginal intercourse, oral sex, or masturbation, with at least one partner in the previous 12 months were considered as sexually active. We analyzed sociodemographic characteristics, self-rated physical and sexual health, comorbid conditions, and medications using multivariate logistic regression models. Overall, 62.3% of men and 37.4% of elderly women were sexually active (P practices were kissing, hugging, and vaginal intercourse. The most common reasons for sexual inactivity were: partner was physically ill (23%), lack of interest (21%), and the man was a widower (23%). This study provided data on sexual activity in older Spanish adults and has identified potential factors that appear to influence sexuality in the elderly with some gender differences. Current results can have implications for healthcare providers for addressing these concerns in an effective manner. © 2011 International Society for Sexual Medicine.

  8. People and things. CERN Courier, Oct 1991, v. 31(8)

    International Nuclear Information System (INIS)

    Anon.

    1991-01-01

    The article reports on achievements of various people, staff changes and position opportunities within the CERN organization and contains news updates on upcoming or past events: ; Hampton University Graduate Studies (HUGS) at CEBAF, a summer program in electromagnetic nuclear physics held at the Continuous Electron Beam Accelerator Facility, Newport News, Virginia, has completed its sixth year. ; With research and development work pushing ahead for the experimental programme at the proposed LHC proton collider in CERN's LEP tunnel, attention is also turning to preparations for the experiments themselves

  9. Using a reflection model for modeling the dynamic feedback path of digital hearing aids

    DEFF Research Database (Denmark)

    Ma, Guilin; Gran, Fredrik; Jacobsen, Finn

    2010-01-01

    Feedback whistling is one of the severe problems with hearing aids, especially in dynamic situations when the users hug, pick up a telephone, etc. This paper investigates the properties of the dynamic feedback paths of digital hearing aids and proposes a model based on a reflection assumption...... gain. The method is also extended to dual-microphone hearing aids to assess the possibility of relating the two dynamic feedback paths through the reflection model. However, it is found that in a complicated acoustic environment, the relation between the two feedback paths can be very intricate...

  10. Finding Support Online: Parents are Finding Comfort and Support in Virtual Hugs

    Science.gov (United States)

    Miller, Janice

    2006-01-01

    When Tamara learned that she and her husband were expecting a baby girl, Tamara remembers the doctor telling her "the odds were high" her daughter would inherit her bipolar disorder. As it turned out, her daughter, Lindsay was also formally diagnosed with bipolar disorder after her 11th birthday. Tamara turned to Internet to find someone who…

  11. HUGS [Hampton University Graduate Studies] at CEBAF [Continuous Electron Beam Accelerator Facility

    International Nuclear Information System (INIS)

    1987-01-01

    This report discusses the following topics: hypernuclear physics with CEBAF emphasis; instructive aspects of few body systems; the three nucleon system: a review of lectures presented by Dr. J.L. Friar; special filter paper analyses and preliminary data derived therefrom; quarks and nuclear physics; perturbative QCD calculations of form factors; basic experimental instrumentation; electromagnetic interactions: the 'Super-Rosenbluth' decomposition; a longitudinal/transverse separation of the 12 C (e.e'p) reaction at quasielastic kinematics; and antiproton form factor from PQCD

  12. Financial-real side interactions in the monetary circuit: loving or dangerous hugs?

    OpenAIRE

    Botta, Alberto; Caverzasi, Eugenio; Tori, Daniele

    2015-01-01

    Monetary circuit theory is one of the most known attempts to formally describe the functioning of a monetary production economy as centered around the concept of flux-reflux of money. Endogenous money creation by commercial banks allows the circuit to open and firms to implement production processes. Financial markets ‘passively’ close the circuit by intermediating savings via bond and equity issuance. Despite its natural focus on financial-real side links, the monetary circuit literature has...

  13. Emotional instability but intact spatial cognition in adenosine receptor 1 knock out mice.

    Science.gov (United States)

    Lang, Undine E; Lang, Florian; Richter, Kerstin; Vallon, Volker; Lipp, Hans-Peter; Schnermann, Jürgen; Wolfer, David P

    2003-10-17

    Several lines of evidence point to the involvement of adenosine in the regulation of important central mechanisms such as cognition, arousal, aggression and anxiety. In order to elucidate the involvement of the adenosine A1 receptor (A1AR) in spatial learning and the control of exploratory behaviour, we assessed A1AR knockout mice (A1AR-/-) and their wild-type littermates (A1AR+/+) in a place navigation task in the water maze and in a battery of forced and free exploration tests. In the water maze, A1AR-/- mice showed normal escape latencies and were indistinguishable from controls with respect to measures of spatial performance during both training and probe trial. But despite normal performance they showed increased wall hugging, most prominently after the relocation of the goal platform for reversal training. Quantitative analysis of strategy choices indicated that wall hugging was increased mainly at the expense of chaining and passive floating, whereas the frequency of trials characterised as direct swims or focal searching was normal in A1AR-/- mice. These results indicate intact spatial cognition, but mildly altered emotional reactions to the water maze environment. In line with this interpretation, A1AR-/- mice showed normal levels and patterns of activity, but a mild increase of some measures of anxiety in our battery of forced and free exploration paradigms. These results are in line with findings published using a genetically similar line, but demonstrate that the magnitude of the changes and the range of affected behavioural measures may vary considerably depending on the environmental conditions during testing.

  14. Monte Carlo cross section testing for thermal and intermediate 235U/238U critical assemblies, ENDF/B-V vs ENDF/B-VI

    International Nuclear Information System (INIS)

    Weinman, J.P.

    1997-06-01

    The purpose of this study is to investigate the eigenvalue sensitivity to changes in ENDF/B-V and ENDF/B-VI cross section data sets by comparing RACER vectorized Monte Carlo calculations for several thermal and intermediate spectrum critical experiments. Nineteen Oak Ridge and Rocky Flats thermal solution benchmark critical assemblies that span a range of hydrogen-to- 235 U (H/U) concentrations (2052 to 27.1) and above-thermal neutron leakage fractions (0.555 to 0.011) were analyzed. In addition, three intermediate spectrum critical assemblies (UH3-UR, UH3-NI, and HISS-HUG) were studied

  15. Hug a Pillow, Slug a Pillow: Using Your Body To Tell the Story.

    Science.gov (United States)

    Miller, Bruce

    2000-01-01

    Presents a sequence of exercises that requires students to think about telling their stories in terms of physicalization. Requires students to think about their blocking: their chosen movements on stage, the gestures they use to communicate their stories, and the business they must create to keep their stories believable and clear. (SC)

  16. Hug tightly and say goodbye: role of endothelial ICAM-1 in leukocyte transmigration.

    Science.gov (United States)

    Rahman, Arshad; Fazal, Fabeha

    2009-04-01

    Stable adhesion of leukocytes to endothelium is crucial for transendothelial migration (TEM) of leukocytes evoked during inflammatory responses, immune surveillance, and homing and mobilization of hematopoietic progenitor cells. The basis of stable adhesion involves expression of intercellular adhesion molecule-1 (ICAM-1), an inducible endothelial adhesive protein that serves as a counter-receptor for beta(2)-integrins on leukocytes. Interaction of ICAM-1 with beta(2)-integrins enables leukocytes to adhere firmly to the vascular endothelium and subsequently, to migrate across the endothelial barrier. The emerging paradigm is that ICAM-1, in addition to firmly capturing leukocytes, triggers intracellular signaling events that may contribute to active participation of the endothelium in facilitating the TEM of adherent leukocytes. The nature, duration, and intensity of ICAM-1-dependent signaling events may contribute to the determination of the route (paracellular vs. transcellular) of leukocyte passage; these aspects of ICAM-1 signaling may in turn be influenced by density and distribution of ICAM-1 on the endothelial cell surface, the source of endothelial cells it is present on, and the type of leukocytes with which it is engaged. This review summarizes our current understanding of the "ICAM-1 paradigm" of TEM with an emphasis on the signaling events mediating ICAM-1 expression and activated by ICAM-1 engagement in endothelial cells.

  17. Quality of life in haemophilia A: Hemophilia Utilization Group Study Va (HUGS-Va).

    Science.gov (United States)

    Poon, J-L; Zhou, Z-Y; Doctor, J N; Wu, J; Ullman, M M; Ross, C; Riske, B; Parish, K L; Lou, M; Koerper, M A; Gwadry-Sridhar, F; Forsberg, A D; Curtis, R G; Johnson, K A

    2012-09-01

    This study describes health-related quality of life (HRQoL) of persons with haemophilia A in the United States (US) and determines associations between self-reported joint pain, motion limitation and clinically evaluated joint range of motion (ROM), and between HRQoL and ROM. As part of a 2-year cohort study, we collected baseline HRQoL using the SF-12 (adults) and PedsQL (children), along with self-ratings of joint pain and motion limitation, in persons with factor VIII deficiency recruited from six Haemophilia Treatment Centres (HTCs) in geographically diverse regions of the US. Clinically measured joint ROM measurements were collected from medical charts of a subset of participants. Adults (N = 156, mean age: 33.5 ± 12.6 years) had mean physical and mental component scores of 43.4 ± 10.7 and 50.9 ± 10.1, respectively. Children (N = 164, mean age: 9.7 ± 4.5 years) had mean total PedsQL, physical functioning, and psychosocial health scores of 85.9 ± 13.8, 89.5 ± 15.2, and 84.1 ± 15.3, respectively. Persons with more severe haemophilia and higher self-reported joint pain and motion limitation had poorer scores, particularly in the physical aspects of HRQoL. In adults, significant correlations (P < 0.01) were found between ROM measures and both self-reported measures. Except among those with severe disease, children and adults with haemophilia have HRQoL scores comparable with those of the healthy US population. The physical aspects of HRQoL in both adults and children with haemophilia A in the US decrease with increasing severity of illness. However, scores for mental aspects of HRQoL do not differ between severity groups. These findings are comparable with those from studies in European and Canadian haemophilia populations. © 2012 Blackwell Publishing Ltd.

  18. Nexo agua-energía: desde el nacimiento del río Llobregat hasta Manresa

    OpenAIRE

    Prieto Márquez, Kelly; Badia Padilla, Ester; Grau Vilalta, Maria Dolors

    2017-01-01

    En este trabajo se estudia el nexo agua-energía en el tramo del río Llobregat desde Castellar de N’hug hasta Manresa. Se lleva a cabo una evaluación de la cantidad de energía necesaria en las estaciones potabilizadoras y depuradoras para adecuar el agua del río, además de determinar la cantidad de energía que generan las centrales mini-hidroeléctricas. Estos dos valores de energía finales son comparados para demostrar si se consume más energía que la que se genera, o al contrario. Se estud...

  19. Expression profiles of mRNA after exposure yeast and rice to heavy-ion radiation

    International Nuclear Information System (INIS)

    Iwahashi, Hitoshi; Mizukami, Satomi; Nojima, Kumie

    2005-01-01

    We have studied expression profiles of mRNA after exposure yeast cells to heavy-ion radiation. Yeast cells was exposed by heavy-ion radiation with the levels of 6, 12, 25, 50, and 100 Gy. We could confirm the reproducibility of physiological state of yeast cells under the experimental conditions by DNA microarray. We could also confirm the reproducibility of viability of yeast cells after exposure to heavy-ion radiation. We thus applied yeast cells exposed with 25 Gy was applied to DNA microarray analysis. The strongly induced genes were HUG1 RAR4 RNR2 for DNA repairing genes and GLC3 GSY1 for energy metabolism genes. (author)

  20. Massive Accidental Overdose of Hydroxyurea in a Young Child with Sickle Cell Anemia

    Science.gov (United States)

    Miller, Scott T.; Rey, Kathy; He, Jin; Flanagan, Jonathan; Fish, Billie J.; Rogers, Zora R.; Wang, Winfred C.; Ware, Russell E.

    2011-01-01

    The Pediatric Hydroxyurea Phase III Clinical Trial (BABY HUG) confirmed safety and efficacy of hydroxyurea therapy for infants with sickle cell anemia. Treatment was associated with reduction in rates of pain, acute chest syndrome, hospitalizations and blood transfusions; improved hematologic values; and, perhaps, preservation of organ function. During the study, a two year-old ingested at one time an entire 35-day supply of hydroxyurea (612 mg/kg body-weight). Despite a serum level of 7,756 μM four hours post-ingestion, the only toxicity was transient mild myelosuppression. With wider usage of hydroxyurea anticipated, conservative management of future overdoses seems reasonable. (ClinicalTrials.gov NCT00006400) PMID:21744485

  1. Mathematical phenomenology of neural stimulation by periodic fields.

    Science.gov (United States)

    Balduzzo, M; Milone, F Ferro; Minelli, T A; Pittaro-Cadore, I; Turicchia, L

    2003-04-01

    Neuron synchronization has been hypothesized as the basic mechanism leading neurological phenomena like low electroencephalographic rhythm dimension or high coherence. Cognitive processes, such as associative memory, can also be explained in terms of neuron synchronization. Inspired by the analysis of an experiment on cortex periodic photostimulation, in resonance conditions, a simple network of integrate and fire (i and f) neurons, has been used to simulate cognitive perturbations by oscillatory and pulsate stimulation of the central nervous system (CNS). In view of realistic simulations of transcranial magnetic stimulation (TMS) phenomena, a discrete extension of the FitzHug-Nagumo nervous fiber model, endowed with regenerative nodes, has been developed too.

  2. Nuclear architecture and landscape: the power plant creates the site

    International Nuclear Information System (INIS)

    Parent, Claude; Bouvier, Yves

    2005-01-01

    The implementation, from 1974, of the French nuclear programme, was associated with an 'Architecture Plan' requested by Michel Hug, Equipment Manager at power utility EDF. The objective was to create an architecture language specific to nuclear power. Far from trying to hide the nuclear power stations, the nuclear architecture college conversely designed one set of ambitious and powerful shapes. Systematically associated to one landscape and to one colourist, the architect sought to use in the best possible way the potentialities available on one site. The power station should not blend in with the landscape, but on the contrary, participate in the creation of a fresh landscape

  3. Field building: lessons from the Robert Wood Johnson Foundation's anthology series.

    Science.gov (United States)

    Isaacs, Stephen L; Knickman, James R

    2005-01-01

    As editors of the Robert Wood Johnson Foundation's (RWJF's) anthology series, we have examined the entire range of the foundation's grant making since 1972. We found that the RWJF has enjoyed considerable success in building fields--from nurse practitioners to tobacco control to end-of-life care. The RWJF has done this by shaping fields as they were emerging, by adopting a wide-ranging "bear hug" approach, and by staying the course. The lessons from the RWJF's field-building efforts are relevant for both large and small foundations: Small funders can develop strategic plans aimed at building fields in their home state or locality.

  4. Diapers Full of?…?Pampered, Hugged, and "Luved" Babies: Teaching Ideological Criticism through Diapers

    Science.gov (United States)

    Wells, Celeste C.

    2016-01-01

    Courses: Communication Criticism, Rhetorical Criticism, Introduction to Rhetoric, Introduction to Communication, Media Studies, and Persuasion courses. Objective: The aim of this activity is to introduce and explain the method of ideological criticism through commonplace advertising.

  5. Design and implementation of an integrated, continuous evaluation, and quality improvement system for a state-based home-visiting program.

    Science.gov (United States)

    McCabe, Bridget K; Potash, Dru; Omohundro, Ellen; Taylor, Cathy R

    2012-10-01

    To describe the design and implementation of an evaluation system to facilitate continuous quality improvement (CQI) and scientific evaluation in a statewide home visiting program, and to provide a summary of the system's progress in meeting intended outputs and short-term outcomes. Help Us Grow Successfully (HUGS) is a statewide home visiting program that provides services to at-risk pregnant/post-partum women, children (0-5 years), and their families. The program goals are to improve parenting skills and connect families to needed services and thus improve the health of the service population. The evaluation system is designed to: (1) integrate evaluation into daily workflow; (2) utilize standardized screening and evaluation tools; (3) facilitate a culture of CQI in program management; and, (4) facilitate scientifically rigorous evaluations. The review of the system's design and implementation occurred through a formative evaluation process (reach, dose, and fidelity). Data was collected through electronic and paper surveys, administrative data, and notes from management meetings, and medical chart review. In the design phase, four process and forty outcome measures were selected and are tracked using standardized screening and monitoring tools. During implementation, the reach and dose of training were adequate to successfully launch the evaluation/CQI system. All staff (n = 165) use the system for management of families; the supervisors (n = 18) use the system to track routine program activities. Data quality and availability is sufficient to support periodic program reviews at the region and state level. In the first 7 months, the HUGS evaluation system tracked 3,794 families (7,937 individuals). System use and acceptance is high. A successful implementation of a structured evaluation system with a strong CQI component is feasible in an existing, large statewide program. The evaluation/CQI system is an effective mechanism to drive modest change in management

  6. [CERN-MEDICIS (Medical Isotopes Collected from ISOLDE): a new facility].

    Science.gov (United States)

    Viertl, David; Buchegger, Franz; Prior, John O; Forni, Michel; Morel, Philippe; Ratib, Osman; Bühler Léo H; Stora, Thierry

    2015-06-17

    CERN-MEDICIS is a facility dedicated to research and development in life science and medical applications. The research platform was inaugurated in October 2014 and will produce an increasing range of innovative isotopes using the proton beam of ISOLDE for fundamental studies in cancer research, for new imaging and therapy protocols in cell and animal models and for preclinical trials, possibly extended to specific early phase clinical studies (phase 0) up to phase I trials. CERN, the University Hospital of Geneva (HUG), the University Hospital of Lausanne (CHUV), the Swiss Institute for Experimental Cancer (ISREC) at Swiss Federal Institutes of Technology (EPFL) that currently support the project will benefit of the initial production that will then be extended to other centers.

  7. RESULTS OF THE SPECIAL BLOOD DONOR DAY

    CERN Document Server

    SC Unit

    2008-01-01

    Responding to the HUG (Hôpitaux Universitaires de Genève) hospitals’ urgent appeal for blood donations during this summer season, the CERN medical staff organised a day of blood donations for the Swiss bloodbank CTS on 30 July. They were supported by NOVAE (Restaurant No. 1), who provided donors with a free snack. This specially arranged campaign was a success, as the 135 volunteers included 66 first-time donors, and a total of 99 standard bags of blood was collected. (Swiss hospitals need 1300 bags every day!) The CTS and CERN’s medical staff want to thank the donors and all others who helped make the event a success. Upcoming blood donor days at CERN: 12 November 2008 and 10 March 2009.

  8. RESULTS OF THE SPECIAL BLOOD DONOR DAY

    CERN Document Server

    SC Unit

    2008-01-01

    Responding to the HUG (Hôpitaux Universitaires de Genève) hospitals’ urgent appeal for blood donations during this summer season, the CERN medical staff organised a day of blood donations for the Swiss bloodbank CTS on 30 July. They were supported by NOVAE (Restaurant No. 1), who provided donors with a free snack. This specially arranged campaign was a success, as the 135 volunteers included 66 first-time donors, and a total of 99 standard bags of blood were collected. (Swiss hospitals need 1300 bags every day!) The CTS and CERN’s medical staff wish to thank the donors and all others who helped make the event a success. Upcoming blood donor days at CERN: 12 November 2008 and 10 March 2009.

  9. Runout distance and dynamic pressure of pyroclastic density currents: Evidence from 18 May 1980 blast surge of Mount St. Helens

    Science.gov (United States)

    Gardner, J. E.; Andrews, B. J.

    2016-12-01

    Pyroclastic density currents (flows and surges) are one of the most deadly hazards associated with volcanic eruptions. Understanding what controls how far such currents will travel, and how their dynamic pressure evolves, could help mitigate their hazards. The distance a ground hugging, pyroclastic density current travels is partly limited by when it reverses buoyancy and lifts off into the atmosphere. The 1980 blast surge of Mount St. Helens offers an example of a current seen to lift off. Before lofting, it had traveled up to 20 km and leveled more than 600 km3 of thick forest (the blowdown zone). The outer edge of the devastated area - where burned trees that were left standing (the singe zone) - is where the surge is thought to have lifted off. We recently examined deposits in the outer parts of the blowdown and in the singe zone at 32 sites. The important finding is that the laterally moving surge travelled into the singe zone, and hence the change in tree damage does not mark the run out distance of the ground hugging surge. Eyewitness accounts and impacts on trees and vehicles reveal that the surge consisted of a fast, dilute "overcurrent" and a slower "undercurrent", where most of the mass (and heat) was retained. Reasonable estimates for flow density and velocity show that dynamic pressure of the surge (i.e., its ability to topple trees) peaked near the base of the overcurrent. We propose that when the overcurrent began to lift off, the height of peak dynamic pressure rose above the trees and stopped toppling them. The slower undercurrent continued forward, burning trees but it lacked the dynamic pressure needed to topple them. Grain-size variations argue that it slowed from 30 m/s when it entered the singe zone to 3 m/s at the far end. Buoyancy reversal and liftoff are thus not preserved in the deposits where the surge lofted upwards.

  10. Management Imperatives of Corruption and Governance Failures in Nigeria

    Directory of Open Access Journals (Sweden)

    John N. N. Ugoani

    2018-03-01

    Full Text Available This study was designed to explore the relationship between neurological substrates of emotional intelligence and human behavior. Neuropsychologists posit that human actions are propelled by the neurons, which allow information to travel through the brain and body, in controlling voluntary and involuntary human behaviours. There is evidence that the connection between the amygdala and the neocortex are hug of operations between head and heart, thought and feeling. This circuitry explains why emotion is very crucial to effective thought and decision making. The architecture of the amygdala interferes with the neurons to ensure that each plays effective role as different neurotransmitters. The survey method was used for the study involving 300 respondents; and it was found that neurological substrates of emotional intelligence have positive relationship with human behavior.

  11. Results of the 24 July blood donation

    CERN Multimedia

    Medical Service

    2013-01-01

    "Bravo! A huge success! A big thanks to everyone involved for their valuable participation this summer," says Ms. Troillet, the nurse responsible for the Transfusion Centre (CTS) at HUG.   During the 24 July blood donation, blood was collected from 109 of the 150 people who attended (including 53 new donors). This excellent result is particularly noteworthy, since blood supplies are at their lowest levels in hospitals during the summer season. The CERN Medical Service joins CTS in thanking all donors for their generous gesture and Ms. Vuattaz, manager of the restaurant NOVAE No. 2 and her team, for their collaboration. Upcoming blood donations:           Wednesday 16 October 2013           Thursday 3 April 2014           Wednesday 23 July 23 2014

  12. The Impact of Training Approaches on Experimental SetUp and Design of Wearable Vibrotactiles for Hunting Dogs

    DEFF Research Database (Denmark)

    Morrison, Ann Judith; Møller, Rune Heide; Manresa-Yee, Cristina

    2016-01-01

    with four hunting dogs who had been trained in either obedience, hunting, competitive or non-competitive styles into the finished design. We contribute to research that incorporates technology to enhance communication and mobility with working and companion animals. We increment foundational research......While designing a wearable vibrotactile solution to assist canine navigation we encountered multiple conflicting dog training methods that impacted heavily on design possibilities as well as the methods used in the experimental design. The VibroTactile Vest (VTV), was designed in an iterative...... process to provide vibrotactile commands to dogs, working with variable-intensity vibrating motors mounted to a modified hug shirt to keep the vibrators close but not restrict movement. We folded knowledge gained from instructional scenarios with trainers, handlers and owners and from working directly...

  13. Beyond Hammers versus Hugs: Leveraging Educator Evaluation and Professional Learning Communities into Job-Embedded Professional Development

    Science.gov (United States)

    Woodland, Rebecca H.; Mazur, Rebecca

    2015-01-01

    Educational evaluation (Ed Eval) and professional learning communities (PLCs) are two of the nation's most predominant approaches to widespread instructional improvement. Yet key attributes of these reform initiatives are too often experienced by teachers as burdensome, or even detrimental, rather than helpful. The authors of this article contend…

  14. Financial–real-side interactions in an extended monetary circuit with shadow banking: Loving or dangerous hugs?

    OpenAIRE

    Botta, Alberto; Caverzasi, Eugenio; Tori, Daniele

    2015-01-01

    Monetary circuit (MC) theory is one of the most interesting attempts to formally describe the functioning of a monetary production economy as centered on the concept of the flux–reflux of money. Endogenous money creation by commercial banks allows the circuit to open and firms to implement production processes. Financial markets “passively” close the circuit by intermediating savings via bond and equity issuance. Despite its natural focus on financial-real side links, the monetary circuit lit...

  15. DVL Velocity Aiding in the HUGIN 1000 Integrated Inertial Navigation System

    Directory of Open Access Journals (Sweden)

    Bjørn Jalving

    2004-10-01

    Full Text Available The RDI WHN-600 Doppler Velocity Log (DVL is a key navigation sensor for the HUG1N 1000 Autonomous Underwater Vehicle (AUV. HUGIN 1000 is designed for autonomous submerged operation for long periods of time. This is facilitated by a low drift velocity aided Inertial Navigation System (INS. Major factors determining the position error growth are the IMU and DVL error characteristics and the mission plan pattern_ For instance, low frequency DVL errors cause an approximately linear drift in a straight-line trajectory, while these errors tend to be cancelled out by a lawn mower pattern_ The paper focuses on the accuracy offered by the DVL. HUGIN 1000 is a permanent organic mine countermeasure (MCM capacity on the Royal Norwegian Navy MCM vessel KNM Karmoy. HUGIN 1000 will be part of the NATO force MCMFORNORTH in fall 2004.

  16. The Drosophila gene CG9918 codes for a pyrokinin-1 receptor

    DEFF Research Database (Denmark)

    Cazzamali, Giuseppe; Torp, Malene; Hauser, Frank

    2005-01-01

    The database from the Drosophila Genome Project contains a gene, CG9918, annotated to code for a G protein-coupled receptor. We cloned the cDNA of this gene and functionally expressed it in Chinese hamster ovary cells. We tested a library of about 25 Drosophila and other insect neuropeptides......, and seven insect biogenic amines on the expressed receptor and found that it was activated by low concentrations of the Drosophila neuropeptide, pyrokinin-1 (TGPSASSGLWFGPRLamide; EC50, 5 x 10(-8) M). The receptor was also activated by other Drosophila neuropeptides, terminating with the sequence PRLamide...... (Hug-gamma, ecdysis-triggering-hormone-1, pyrokinin-2), but in these cases about six to eight times higher concentrations were needed. The receptor was not activated by Drosophila neuropeptides, containing a C-terminal PRIamide sequence (such as ecdysis-triggering-hormone-2), or PRVamide (such as capa...

  17. GAC-EPA

    CERN Multimedia

    GAC-EPA

    2014-01-01

    Études des hôpitaux universitaires de Genève Santé osseuse, prévention des fractures, vieillir en bonne santé !   Appel à volontaires pour recherches menées par le service des maladies osseuses des HUG : Vous êtes une femme ou un homme âgé(e) de… … 65 ans à 69 ans Participez à une étude « Santé osseuse et prévention des fractures » sur l’ostéoporose et les fractures visant à identifier vos facteurs de risques environnementaux (antécédents, alimentation, activité physique) et la composante héréditaire sur la densité minérale et l’architecture osseuse. Si vous êtes intéressé(e), veuillez téléphoner au 004122 372 71 83...

  18. Butterflies of the Rice Research Station and adjoining locality in Chinsurah, West Bengal, India

    Directory of Open Access Journals (Sweden)

    Somnath Mandal

    2016-05-01

    Full Text Available Chinsurah is a small town on the western bank of the Hugli River, a distributary of the river Ganges.  A survey from November 2006 to June 2014 with photographic documentation on the butterfly community in Chinsurah revealed the presence of a total of 70 species representing 53 genera in five families; most dominant family was the Nymphalidae having 34.3% of the total species.  Six species are legally protected; one species under Schedule I; three species under Schedule II; and two species under Schedule IV of the Indian Wildlife (Protection Act, 1972.  Rare species like Pareronia avator (Moore, Mahathala ameria (Hewitson and Melanitis zitenius (Herbst were recorded in this rapidly degrading habitat.  This study may help in planning conservation strategies in urban areas and sustainable development as well. 

  19. HUGS at CEBAF: Proceedings of the Hampton University Graduate Studies at the Continuous Electron Beam Accelerator Facility

    International Nuclear Information System (INIS)

    Buck, W.W.

    1989-01-01

    This report contains papers on the following topics: breaking and restoration of Chiral symmetry; an introduction to the QCD quark model and hadron spectroscopy; observations of ultra high energy emission from Cygnus X-3; parity violation program at CEBAF; testing the standard model via nuclear current interactions; collective models in excited nuclei and excited baryons; cold fusion; Δ electroproduction and inelastic charge scattering from carbon and iron; electron scattering and sum rules in nuclear physics; nuclear matter saturation in a U(1) circle-times Chiral model; effective action in path integral approach for a scalar field theory; many body approach to electron scattering; non-resonant N-N pion production; large N c expansion, from QCD to Skyrme; relativistic methods for few-body systems; and structure of excited nuclei and baryons (breaking of reflection symmetry)

  20. Comparison of different techniques for in microgravity-a simple mathematic estimation of cardiopulmonary resuscitation quality for space environment.

    Science.gov (United States)

    Braunecker, S; Douglas, B; Hinkelbein, J

    2015-07-01

    Since astronauts are selected carefully, are usually young, and are intensively observed before and during training, relevant medical problems are rare. Nevertheless, there is a certain risk for a cardiac arrest in space requiring cardiopulmonary resuscitation (CPR). Up to now, there are 5 known techniques to perform CPR in microgravity. The aim of the present study was to analyze different techniques for CPR during microgravity about quality of CPR. To identify relevant publications on CPR quality in microgravity, a systematic analysis with defined searching criteria was performed in the PubMed database (http://www.pubmed.com). For analysis, the keywords ("reanimation" or "CPR" or "resuscitation") and ("space" or "microgravity" or "weightlessness") and the specific names of the techniques ("Standard-technique" or "Straddling-manoeuvre" or "Reverse-bear-hug-technique" or "Evetts-Russomano-technique" or "Hand-stand-technique") were used. To compare quality and effectiveness of different techniques, we used the compression product (CP), a mathematical estimation for cardiac output. Using the predefined keywords for literature search, 4 different publications were identified (parabolic flight or under simulated conditions on earth) dealing with CPR efforts in microgravity and giving specific numbers. No study was performed under real-space conditions. Regarding compression depth, the handstand (HS) technique as well as the reverse bear hug (RBH) technique met parameters of the guidelines for CPR in 1G environments best (HS ratio, 0.91 ± 0.07; RBH ratio, 0.82 ± 0.13). Concerning compression rate, 4 of 5 techniques reached the required compression rate (ratio: HS, 1.08 ± 0.11; Evetts-Russomano [ER], 1.01 ± 0.06; standard side straddle, 1.00 ± 0.03; and straddling maneuver, 1.03 ± 0.12). The RBH method did not meet the required criteria (0.89 ± 0.09). The HS method showed the highest cardiac output (69.3% above the required CP), followed by the ER technique (33

  1. Sexual harassment of the physiotherapist in South Africa

    Directory of Open Access Journals (Sweden)

    L. Bütow-Dûtoit

    2006-01-01

    Full Text Available No study  has been conducted on sexual harassment of physiotherapists in South Africa and it is therefore not known whether harassment occurs and if it does, to what extent. To this purpose, a questionnaire on  sexual harassment and other sexual-related issues in the physiotherapy work environment in South Africa, was sent to a random selection of  982 physiotherapists registered with the Health Professions Council of South Africa. The response rate was 32%. This paper presents the results of the first half of the questionnaire, which was devoted to sexual harassment of the physiotherapist.  Approximately 60% had experienced sexual harassment, of which 83.98% had been perpetrated by patients. Only 5.82% of the respondents had received some form of information in this regard. The most common form of harassment was requests for a hug or kiss.

  2. HUGS at CEBAF [Hampton University Graduate Studies at the Continuous Electron Beam Accelerator Facility] June 6--24, 1988

    International Nuclear Information System (INIS)

    1988-01-01

    Topics discussed in this paper are: Physics thru the last 80 years; low energy neutron physics at LAMPF; experiments on P-violation; nucleon structure structure and nucleon resonances; electro-excitation of nucleon resonances; electron scattering (e,e'p) experiments; quasielastic scattering of electron with nucleus (introduction to (e,e'P) experiment); CEBAF's machine; quantum hadrodynamics-QHD-1 the Walecka model; relativistic nuclear dynamics; hybrid models and QCD; and modeling confinement: poor man's version

  3. Research project: "Promotion of optimum brain ageing"

    CERN Multimedia

    IT Department

    2009-01-01

    The Rehabilitation and Geriatrics Department of the Geneva University Hospitals (HUG) has signed a research protocol with CERN with a view to promoting better understanding of the mechanisms that trigger Alzheimer’s disease. Alzheimer’s disease is a form of dementia associated with memory loss, inability to make plans and spatial disorientation. With 24 million sufferers worldwide at present, a figure that is predicted to rise to 29 million by 2020, it represents a major challenge for the coming decades. Prevention is a key factor in slowing the alarming spread of this disease. Delaying the onset of the disease could reduce the total number of cases by 50%. Why CERN? CERN is an international research organisation with a workforce that is predominantly male (a section of the population that has been little studied so far) and has a high level of education. Moreover, its pensioners are easy to reach since the majority live in the Geneva area. The aim of the study is to ev...

  4. 108TH ACCU Meeting

    CERN Multimedia

    2015-01-01

    Agenda for the meeting to be held on Tuesday, 9 June 2015 at 9.15 a.m. in room Georges Charpak (Room F, 60-6-015): Chairperson's remarks Adoption of the agenda      Minutes of the previous meeting Report on services from GS Department a. General Services b. Collaboration between CERN and HUG Report on services from IT Department 50th anniversary of the CERN Bulletin News from the CERN Management Progress on Health Insurance for Users Users’ Office News Reports from ACCU representatives on other Committees a. Restaurants' Supervisory committee Matters arising Any Other Business Agenda for the next meeting   Anyone wishing to raise any points under “Any Other Business” is invited to send them to the Chairperson in writing or by e-mail to ACCU.Secretary@cern.ch. Michael Hauschild (Secretary) ACCU is a forum for discussion between the CERN Management and representatives of the CERN Us...

  5. A hospital-wide clinical findings dictionary based on an extension of the International Classification of Diseases (ICD).

    Science.gov (United States)

    Bréant, C; Borst, F; Campi, D; Griesser, V; Momjian, S

    1999-01-01

    The use of a controlled vocabulary set in a hospital-wide clinical information system is of crucial importance for many departmental database systems to communicate and exchange information. In the absence of an internationally recognized clinical controlled vocabulary set, a new extension of the International statistical Classification of Diseases (ICD) is proposed. It expands the scope of the standard ICD beyond diagnosis and procedures to clinical terminology. In addition, the common Clinical Findings Dictionary (CFD) further records the definition of clinical entities. The construction of the vocabulary set and the CFD is incremental and manual. Tools have been implemented to facilitate the tasks of defining/maintaining/publishing dictionary versions. The design of database applications in the integrated clinical information system is driven by the CFD which is part of the Medical Questionnaire Designer tool. Several integrated clinical database applications in the field of diabetes and neuro-surgery have been developed at the HUG.

  6. Aspects of ribonucleotide reductase regulation and genome stability

    DEFF Research Database (Denmark)

    Nielsen, Helena Berner Nedergaard

    yeast, and Sml1, Hug1, and Dif1 in budding yeast. An elevated, as well as a reduced dNTP pool is shown to lead to an increase in spontaneous mutation rates, hence regulation of RNR is very important in order to maintain genomic stability. No human inhibitory proteins have yet been identified to regulate....... RNR consists of two subunits: R1 and R2, both of which are essential. The activity of RNR is strictly regulated to control the dNTP pool, both by allosteric feedback control and transcriptional and translational controls. Four inhibitory proteins of RNR have been identified in yeast: Spd1 in fission...... the human RNR enzyme. In this study regulation of human RNR was investigated using a fission yeast strain that depended solely on the human genes of R1 and R2 for dNTP synthesis. Even though this strain could grow like wild-type fission yeast it was hypersensitive to hydroxyurea (HU) and depended...

  7. Reduced optimism and a heightened neural response to everyday worries are specific to generalized anxiety disorder, and not seen in social anxiety.

    Science.gov (United States)

    Blair, K S; Otero, M; Teng, C; Geraci, M; Ernst, M; Blair, R J R; Pine, D S; Grillon, C

    2017-07-01

    Generalized anxiety disorder (GAD) and social anxiety disorder (SAD) are co-morbid and associated with similar neural disruptions during emotion regulation. In contrast, the lack of optimism examined here may be specific to GAD and could prove an important biomarker for that disorder. Unmedicated individuals with GAD (n = 18) and age-, intelligence quotient- and gender-matched SAD (n = 18) and healthy (n = 18) comparison individuals were scanned while contemplating likelihoods of high- and low-impact negative (e.g. heart attack; heartburn) or positive (e.g. winning lottery; hug) events occurring to themselves in the future. As expected, healthy subjects showed significant optimistic bias (OB); they considered themselves significantly less likely to experience future negative but significantly more likely to experience future positive events relative to others (p optimism and increased worry about everyday events in GAD. Consistent with this possibility, patients with SAD did not show such dysfunction. Future studies should consider if this dysfunction represents a biomarker for GAD.

  8. Impact of silver nanoparticles on benthic prokaryotes in heavy metal-contaminated estuarine sediments in a tropical environment.

    Science.gov (United States)

    Antizar-Ladislao, B; Bhattacharya, B D; Ray Chaudhuri, S; Sarkar, S K

    2015-10-15

    Little knowledge is available about the potential impact of commercial silver nanoparticles (Ag-NPs) on estuarine microbial communities. The Hugli river estuary, India, is susceptible to heavy metals pollution through boat traffic, and there is the potential for Ag-NP exposure via effluent discharged from ongoing municipal and industrial activities located in close proximity. This study investigated the effects of commercial Ag-NPs on native microbial communities in estuarine sediments collected from five stations, using terminal restriction fragment length polymorphism (T-RFLP) technique. An increase in the number of bacteria in consortium in sediments was observed following exposure to Ag-NPs. In general microbial communities may be resistant in estuarine systems to the antimicrobial effects of commercial Ag-NPs, but key microorganisms, such as Pelobacter propionicus, disappeared following exposure to Ag-NPs. In conclusion, the T-RFLP analysis indicated that Ag-NPs have the potential to shape estuarine sediment bacterial community structure. Copyright © 2015 Elsevier Ltd. All rights reserved.

  9. Volcanic lightning and plume behavior reveal evolving hazards during the April 2015 eruption of Calbuco volcano, Chile

    Science.gov (United States)

    Van Eaton, Alexa; Amigo, Álvaro; Bertin, Daniel; Mastin, Larry G.; Giacosa, Raúl E; González, Jerónimo; Valderrama, Oscar; Fontijn, Karen; Behnke, Sonja A

    2016-01-01

    Soon after the onset of an eruption, model forecasts of ash dispersal are used to mitigate the hazards to aircraft, infrastructure and communities downwind. However, it is a significant challenge to constrain the model inputs during an evolving eruption. Here we demonstrate that volcanic lightning may be used in tandem with satellite detection to recognize and quantify changes in eruption style and intensity. Using the eruption of Calbuco volcano in southern Chile on 22-23 April 2015, we investigate rates of umbrella cloud expansion from satellite observations, occurrence of lightning, and mapped characteristics of the fall deposits. Our remote-sensing analysis gives a total erupted volume that is within uncertainty of the mapped volume (0.56 ±0.28 km3 bulk). Observations and volcanic plume modeling further suggest that electrical activity was enhanced both by ice formation in the ash clouds >10 km asl and development of a low-level charge layer from ground-hugging currents.

  10. Floods in Central Texas, September 7-14, 2010

    Science.gov (United States)

    Winters, Karl E.

    2012-01-01

    Severe flooding occurred near the Austin metropolitan area in central Texas September 7–14, 2010, because of heavy rainfall associated with Tropical Storm Hermine. The U.S. Geological Survey, in cooperation with the Upper Brushy Creek Water Control and Improvement District, determined rainfall amounts and annual exceedance probabilities for rainfall resulting in flooding in Bell, Williamson, and Travis counties in central Texas during September 2010. We documented peak streamflows and the annual exceedance probabilities for peak streamflows recorded at several streamflow-gaging stations in the study area. The 24-hour rainfall total exceeded 12 inches at some locations, with one report of 14.57 inches at Lake Georgetown. Rainfall probabilities were estimated using previously published depth-duration frequency maps for Texas. At 4 sites in Williamson County, the 24-hour rainfall had an annual exceedance probability of 0.002. Streamflow measurement data and flood-peak data from U.S. Geological Survey surface-water monitoring stations (streamflow and reservoir gaging stations) are presented, along with a comparison of September 2010 flood peaks to previous known maximums in the periods of record. Annual exceedance probabilities for peak streamflow were computed for 20 streamflow-gaging stations based on an analysis of streamflow-gaging station records. The annual exceedance probability was 0.03 for the September 2010 peak streamflow at the Geological Survey's streamflow-gaging stations 08104700 North Fork San Gabriel River near Georgetown, Texas, and 08154700 Bull Creek at Loop 360 near Austin, Texas. The annual exceedance probability was 0.02 for the peak streamflow for Geological Survey's streamflow-gaging station 08104500 Little River near Little River, Texas. The lack of similarity in the annual exceedance probabilities computed for precipitation and streamflow might be attributed to the small areal extent of the heaviest rainfall over these and the other gaged

  11. The n,{gamma} discrimination in recoil-proton proportional counters. Application to the measurement of fast neutron spectra; Discrimination n,{gamma} dans les compteurs proportionnels a protons de recul. Application a la mesure des spectres de neutrons rapides

    Energy Technology Data Exchange (ETDEWEB)

    Jeandidier, C [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1969-07-01

    A description is given of a spectrometry chain working in the energy range of a few keV to 1 MeV, and designed for measurement of fast neutron spectra. It consists of detectors, recoil proton proportional counters built especially for this work by R. COMTE (DEG/SER) and which make it possible to cover the energy range and also associated electronic equipment. A brief description is first given of the physical processes involved: (n,p) collisions in the gas, influence of {gamma} radiation; the method of discrimination is then presented. It is based on the difference in the rise-times of the pulses. In the experiments described here the use of a bi-parametric system made it possible to employ the most simple discrimination device, based on the fact that the high frequency gamma pulse components are, at a given energy, weaker than those of the neutron pulses. Results are given of measurements carried out on the Van der Graaff (mono-energetic neutrons for testing the linearity of the chain and the resolving power of the counters), and of those made in a sub-critical system Hug at Cadarache. (author) [French] On decrit une chaine de spectrometrie travaillant dans le domaine d'energie de quelques keV a 1 MeV destinee a la mesure des spectres de neutrons rapides. Elle comprend les detecteurs, compteurs proportionnels a protons de recul, realises specialement pour cette etude par M. R. COMTE (DEG/SER), permettant de couvrir la gamme d'energie et l'electronique associee. Apres un rappel des processus physiques mis en jeu: chocs (n,p) dans les gaz, influence des rayonnements {gamma}, on expose la methode de discrimination utilisee. Celle-ci est basee sur la difference des temps de montee des impulsions. Au cours des experiences rapportees ici, la mise en oeuvre d'un ensemble bi-parametrique a permis d'utiliser le dispositif de discrimination le plus simple, base sur la remarque que les composantes a haute frequence des impulsions {gamma} sont, a energie egale, plus faibles

  12. The n,{gamma} discrimination in recoil-proton proportional counters. Application to the measurement of fast neutron spectra; Discrimination n,{gamma} dans les compteurs proportionnels a protons de recul. Application a la mesure des spectres de neutrons rapides

    Energy Technology Data Exchange (ETDEWEB)

    Jeandidier, C. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1969-07-01

    A description is given of a spectrometry chain working in the energy range of a few keV to 1 MeV, and designed for measurement of fast neutron spectra. It consists of detectors, recoil proton proportional counters built especially for this work by R. COMTE (DEG/SER) and which make it possible to cover the energy range and also associated electronic equipment. A brief description is first given of the physical processes involved: (n,p) collisions in the gas, influence of {gamma} radiation; the method of discrimination is then presented. It is based on the difference in the rise-times of the pulses. In the experiments described here the use of a bi-parametric system made it possible to employ the most simple discrimination device, based on the fact that the high frequency gamma pulse components are, at a given energy, weaker than those of the neutron pulses. Results are given of measurements carried out on the Van der Graaff (mono-energetic neutrons for testing the linearity of the chain and the resolving power of the counters), and of those made in a sub-critical system Hug at Cadarache. (author) [French] On decrit une chaine de spectrometrie travaillant dans le domaine d'energie de quelques keV a 1 MeV destinee a la mesure des spectres de neutrons rapides. Elle comprend les detecteurs, compteurs proportionnels a protons de recul, realises specialement pour cette etude par M. R. COMTE (DEG/SER), permettant de couvrir la gamme d'energie et l'electronique associee. Apres un rappel des processus physiques mis en jeu: chocs (n,p) dans les gaz, influence des rayonnements {gamma}, on expose la methode de discrimination utilisee. Celle-ci est basee sur la difference des temps de montee des impulsions. Au cours des experiences rapportees ici, la mise en oeuvre d'un ensemble bi-parametrique a permis d'utiliser le dispositif de discrimination le plus simple, base sur la remarque que les composantes a haute frequence des impulsions {gamma} sont, a

  13. When Cars Hit Trucks and Girls Hug Boys: The Effect of Animacy on Word Order in Gestural Language Creation.

    Science.gov (United States)

    Kocab, Annemarie; Lam, Hannah; Snedeker, Jesse

    2018-04-01

    A well-known typological observation is the dominance of subject-initial word orders, SOV and SVO, across the world's languages. Recent findings from gestural language creation paradigms offer possible explanations for the prevalence of SOV. When asked to gesture transitive events with an animate agent and inanimate patient, gesturers tend to produce SOV order, regardless of their native language biases. Interestingly, when the patient is animate, gesturers shift away from SOV to use of other orders, like SVO and OSV. Two competing hypotheses have been proposed for this switch: the noisy channel account (Gibson et al., 2013) and the role conflict account (Hall, Mayberry, & Ferreira, 2013). We set out to distinguish between these two hypotheses, disentangling event reversibility and patient animacy, by looking at gestural sequences for events with two inanimate participants (inanimate-inanimate, reversible). We replicated the previous findings of a preference for SOV order when describing animate-inanimate, irreversible events as well as a decrease in the use of SOV when presented with animate-animate, reversible events. Accompanying the drop in SOV, in a novel condition we observed an increase in the use of SVO and OSV orders when describing events involving two animate entities. In sum, we find that the observed avoidance of SOV order in gestural language creation paradigms when the event includes an animate agent and patient is driven by the animacy of the participants rather than the reversibility of the event. We suggest that findings from gestural creation paradigms are not automatically linkable to spoken language typology. Copyright © 2017 Cognitive Science Society, Inc.

  14. Osteoporosis screening campaign at the Hôpital Cantonal

    CERN Multimedia

    IT Department

    2008-01-01

    The bone diseases department of Geneva’s Teaching Hospitals (HUG) is launching a major study* on osteoporosis, aiming to identify the risk factors for this disease and to assess the hereditary component of bone structure. Osteoporosis is a common bone disease manifesting itself in people over the age of 65 through increased bone fragility and the high risk of fractures. This study is being carried out on men and women between the ages of 63 and 67 living in the Geneva region. The CERN Medical Service, the CERN and ESO pensioners associations (GACEPA) and the CHIS Board all support this public health initiative and strongly urge you, your spouse, colleagues and friends to take part in the campaign and obtain a free evaluation of your bone mass by the relevant specialised hospital services. The person to contact is Dr CLAIRE DUROSIER at 022 372 71 83 from 9.00 a.m. to 6.00 p.m., Mondays to Fridays, or by e-mail on mailto:claire.durosier@netcourrier.com Participation free of charge. Strict confidentiality assu...

  15. Osteoporosis screening campaign at the Hôpital Cantonal

    CERN Multimedia

    SC Unit

    2008-01-01

    The bone diseases department of Geneva’s Teaching Hospitals (HUG) is launching a major study* on osteoporosis, aiming to identify the risk factors for this disease and to assess the hereditary component of bone structure. Osteoporosis is a common bone disease manifesting itself in people over the age of 65 through increased bone fragility and the high risk of fractures. This study is being carried out on men and women between the ages of 63 and 67 living in the Geneva region. The CERN Medical Service, the CERN and ESO pensioners associations (GACEPA) and the CHIS Board all support this public health initiative and strongly urge you, your spouse, colleagues and friends to take part in the campaign and obtain a free evaluation of your bone mass by the relevant specialised hospital services. The person to contact is Dr CLAIRE DUROSIER (tel. 022 372 71 83 from 9.00 a.m. to 6.00 p.m., Mondays to Fridays, or e-mail: mailto:claire.durosier@netcourrier.com). Participation free of ...

  16. Observers' reaction to parent-child intimacy.

    Science.gov (United States)

    Hewitt, J; Walker, B

    2001-02-01

    A study was carried out to examine how people react to acts of intimacy between parent and child. Based on an extensive series of studies reported in 1998 by Reis who found less intimate interactions between two men who are friends than between men or women or between two women who are friends, it was reasoned that intimacy between two males may violate norms of our culture, so it was predicted that people would react less favorably to intimacy between father and son than to intimacy between father and daughter, mother and daughter, or mother and son. Men (n = 19) and women (n=26), most of whom were 18-24 years of age, read versions of a mother or father having an intimate interaction (lap-sit, hair-stroke, hug/kiss) with an 11-yr.-old daughter or son and then rated the act on a 7-point scale from good to bad. As predicted, the undergraduates rated intimate interactions between father and son less favorably than those between father and daughter, mother and daughter, and mother and son.

  17. Kinetics and dynamics of nanosecond streamer discharge in atmospheric-pressure gas bubble suspended in distilled water under saturated vapor pressure conditions

    KAUST Repository

    Sharma, Ashish

    2016-09-08

    We perform computational studies of nanosecond streamer discharges generated in helium bubbles immersed in distilled water under atmospheric pressure conditions. The model takes into account the presence of water vapor in the gas bubble for an accurate description of the discharge kinetics. We find that the dynamic characteristics of the streamer discharge are different at low and high positive trigger voltages with the axial streamer evolution dominant for low voltages and a surface hugging mode favored for high voltages. We also find a substantial difference in initiation, transition and evolution stages of discharge for positive and negative trigger voltages with the volumetric distribution of species in the streamer channel much more uniform for negative trigger voltages on account of the presence of multiple streamers. We observe that the presence of water vapor does not affect the breakdown voltage even for oversaturated conditions but significantly influences the composition of dominant species in the trail of the streamer as well as the flux of the dominant species on the bubble surface. © 2016 IOP Publishing Ltd.

  18. Diffusion in Altered Tonalite Sample Using Time Domain Diffusion Simulations in Tomographic Images Combined with Lab-scale Diffusion Experiments

    Science.gov (United States)

    Voutilainen, M.; Sardini, P.; Togneri, L.; Siitari-Kauppi, M.; Timonen, J.

    2010-12-01

    In this work an effect of rock heterogeneity on diffusion was investigated. Time domain diffusion simulations were used to compare behavior of diffusion in homogeneous and heterogeneous 3D media. Tomographic images were used as heterogeneous rock media. One altered tonalite sample from Sievi, Finland, was chosen as test case for introduced analysis procedure. Effective diffusion coefficient of tonalite sample was determined with lab-scale experiments and the same coefficient was used also for homogeneous media. Somewhat technically complicated mathematical solution for analysis of through diffusion experiment is shortly described. Computed tomography (CT) is already quite widely used in many geological, petrological, and paleontological applications when the three-dimensional (3D) structure of the material is of interest, and is an excellent method for gaining information especially about its heterogeneity, grain size, or porosity. In addition to offering means for quantitative characterization, CT provides a lot of qualitative information [1]. A through -diffusion laboratory experiment using radioactive tracer was fitted using the Time Domain Diffusion (TDD) method. This rapid particle tracking method allows simulation of the heterogeneous diffusion based on pore-scale images and local values of diffusivities [2]. As a result we found out that heterogeneity has only a small effect to diffusion coefficient and in-diffusion profile for used geometry. Also direction dependency was tested and was found to be negligible. Whereas significant difference between generally accepted value and value obtained from simulations for constant m in Archie’s law was found. [1] Voutilainen, M., Siitari-Kauppi, M., Sardini, P., and Timonen, J., (2010). On pore-space characterization of an altered tonalite by X-ray µCT and the 14C-PMMA method (in progress). [2] Sardini, P., Robinet, J., Siitari-Kauppi, M., Delay, F., and Hellmuth, K-H, (2007). On direct simulation of heterogeneous

  19. Fire effects on the Point Reyes Mountain Beaver (Aplodontia rufa phaea) at Point Reyes National Seashore, 10 years after the Vision Fire

    Science.gov (United States)

    Fellers, Gary M.; Osbourn, Michael

    2009-01-01

    The 1995 Vision Fire burned 5000 ha and destroyed 40% of the habitat of the Point Reyes Mountain Beaver (Aplodontia rufa phaea). Surveys immediately post-fire and in 2000 showed that only 0.4 to 1.7% of Mountain Beavers within the burn area survived. In 2000, dense, ground-hugging Blue-blossom Ceanothus (Ceanothus thrysiflorus) appeared to make coastal scrub thickets much less suitable for Mountain Beavers even though the number of burrows at our 11 study sites had returned to 88% of pre-fire numbers. In 2005 (10 y post-fire), the habitat appeared to be better for Mountain Beavers; Blue-blossom Ceanothus had diminished and vegetation more typical of northern coastal scrub, such as Coyote Brush (Baccharis pilularis) overstory with a lower layer of herbaceous vegetation, had greatly increased; but the number of Mountain Beaver burrows had declined to 52% of pre-fire numbers and there was little change in the number of sites occupied between our 2000 and 2005 surveys. With the expected successional changes in thicket structure, Mountain Beaver populations are likely to recover further, but there will probably be considerable variation in how each population stabilizes.

  20. The unique functioning of a pre-Columbian Amazonian floodplain fishery.

    Science.gov (United States)

    Blatrix, Rumsaïs; Roux, Bruno; Béarez, Philippe; Prestes-Carneiro, Gabriela; Amaya, Marcelo; Aramayo, Jose Luis; Rodrigues, Leonor; Lombardo, Umberto; Iriarte, Jose; de Souza, Jonas Gregorio; Robinson, Mark; Bernard, Cyril; Pouilly, Marc; Durécu, Mélisse; Huchzermeyer, Carl F; Kalebe, Mashuta; Ovando, Alex; McKey, Doyle

    2018-04-16

    Archaeology provides few examples of large-scale fisheries at the frontier between catching and farming of fish. We analysed the spatial organization of earthen embankments to infer the functioning of a landscape-level pre-Columbian Amazonian fishery that was based on capture of out-migrating fish after reproduction in seasonal floodplains. Long earthen weirs cross floodplains. We showed that weirs bear successive V-shaped features (termed 'Vs' for the sake of brevity) pointing downstream for outflowing water and that ponds are associated with Vs, the V often forming the pond's downstream wall. How Vs channelled fish into ponds cannot be explained simply by hydraulics, because Vs surprisingly lack fishways, where, in other weirs, traps capture fish borne by current flowing through these gaps. We suggest that when water was still high enough to flow over the weir, out-migrating bottom-hugging fish followed current downstream into Vs. Finding deeper, slower-moving water, they remained. Receding water further concentrated fish in ponds. The pond served as the trap, and this function shaped pond design. Weir-fishing and pond-fishing are both practiced in African floodplains today. In combining the two, this pre-Columbian system appears unique in the world.

  1. [The sleeping disease drug Germanine as an instrument for propaganda: reception in literature and film during National Socialism].

    Science.gov (United States)

    Jacobi, Eva Anne

    2010-01-01

    As European colonization spread widely over the African continent the health and physical welfare of the African population gained more and more importance to European colonists who concentrated on capitalizing on African human resources for an improved financial and economic outcome of their colonies. This brought tropical medicine to the top of the European colonial agenda and raised the awareness of the threat of infectious diseases, such as the African Trypanosomiasis or so-called sleeping disease. In 1916 a group of scientists from the pharmaceutical company Bayer AG discovered a substance on the base of dye rather than arsenic. The drug was called Bayer 205 and showed outstanding therapeutic effects. It also reduced adverse reactions in people infected with sleeping disease. As Germany had already lost its colonies, the Bayer company--supported by the German government--negotiated with the English and Belgian governments and was allowed to send an expedition to East Africa. During 1921 and 1923 the new drug was tested in English Rhodesia and Belgian Congo and proved revolutionary, especially in comparison with conventional substances. In due course, the drug Bayer 205 was named Germanin and it was subsequently proposed to use it for political leverage: knowledge and use of the new drug was to be given only in exchange for parts of the former German colonies. However, the reactions of the international media put an end to Germany's neo-colonial-dreams, even before the proposal had reached governmental level. Even so, the incident never disappeared from the mind of those who wished to revive German colonialism. Thus, it is no surprise, that the tale of the discovery and perceived "injustice" of a thwarted scientific success regained an important place in National Socialist propaganda. This article will examine two sources to exemplify the role Germanin attained in National Socialist propaganda: Hellmuth Unger's popular science novel Germanin. Geschichte einer

  2. Beyond "Lots of Hugs and Kisses": Expressions of Parental Love From Parents and Their Young Children in Two-Parent, Financially Stable Families.

    Science.gov (United States)

    Sabey, Allen K; Rauer, Amy J; Haselschwerdt, Megan L; Volling, Brenda

    2017-10-22

    Given that parental love is essential for children's optimal development, the current study gathered examples of how parental love was demonstrated within parent-child relationships. Fifty-eight two-parent, financially stable families consisting of a mother, father, and young child (3-7 years old) from the Midwest were interviewed regarding how they demonstrated or perceived parental love. Results from an inductive thematic analysis revealed considerable variability in how parental love was demonstrated, with five themes emerging that overlapped between parents and their children: playing or doing activities together, demonstrating affection, creating structure, helping or supporting, and giving gifts or treats. Some gendered patterns among these themes were found with mothers emphasizing physical and verbal affection and fathers highlighting their more prominent role as playmates. The lay examples provided by parents and children in this exploratory study extend previous conceptualizations of parental love and underscore the importance of parents being attuned and responsive to the specific needs of their children. © 2017 Family Process Institute.

  3. Neutron study of fast neutron reactor systems by exponential experiments on Harmonie - Graphite program HUG-PHUG - Oxide program PHRIXOS - Uranium program UK

    International Nuclear Information System (INIS)

    Desprets, Alain.

    1977-12-01

    Exponential experiments allow to obtain the fundamental characteristics of a lattice (material buckling, reaction rate ratios) more economically than critical experiments. This report describes the experimental techniques and the methods of analysis used for this type of experiments. The results obtained with three programs performed with the source reactor HARMONIE are given: graphite-lattices program (3 U-fueled and 3 Pu-fueled lattices); oxide-fuel program (4 PuO 2 -UO 2 lattices); pure uranium program (one lattice). Some of these lattices were also studied in critical experiments. The coherence of the results obtained by the two types of experiments is established [fr

  4. An astrophysical engine that stores gravitational work as nuclear Coulomb energy

    Science.gov (United States)

    Clayton, Donald

    2014-03-01

    I describe supernovae gravity machines that store large internal nuclear Coulomb energy, 0.80Z2A- 1 / 3MeV per nucleus. Excess of it is returned later by electron capture and positron emission. Decay energy manifests as (1) observable gamma-ray lines (2) light curves of supernovae (3) chemical energy of free carbon dissociated from CO molecules (4) huge abundances of radiogenic daughters. I illustrate by rapid silicon burning, a natural epoch in SN II. Gravitational work produces the high temperatures that photoeject nucleons and alpha particles from heavy nuclei. These are retained by other nuclei to balance photoejection rates (quasiequilibrium). The abundance distribution adjusts slowly as remaining abundance of Z = N 28Si decomposes, so p, n, α recaptures hug the Z = N line. This occurs in milliseconds, too rapidly for weak decay to alter bulk Z/N ratio. The figure displays those quasiequilibrium abundances color-coded to their decays. Z = N = 2k nuclei having k 10 are radioactive owing to excess Coulomb energy. Weak decays radiate that excess energy weeks later to fuel the four macroscopic energetic phenomena cited. How startling to think of the Coulomb nuclear force as storing cosmic energy and its weak decay releasing macroscopic activation to SNII.

  5. Information and support for co-survivors during or after cancer treatment: Consideration of Un Abrazo Para la Familia as a model for family-focused intervention in cancer rehabilitation.

    Science.gov (United States)

    Marshall, Catherine A; Curran, Melissa A; Koerner, Susan Silverberg; Weihs, Karen L; Hickman, Amy C; García, Francisco A R

    2013-01-01

    The development and evaluation of Un Abrazo Para La Familia, [A Hug for the Family] is described. Un Abrazo is discussed as an effective model of education, information-sharing, and skill-building for use with low-income co-survivors of cancer. Sixty co-survivors participated. The majority were women and all reported being Hispanic. Using quantitative data (N=60), the needs, concerns, and characteristics of the co-survivor population served through Un Abrazo are presented. Further, we offer three qualitative case studies (with one co-survivor, one survivor, and one non-participant) to illustrate the model and its impact. The median level of education level of co-survivors was 12 years. The majority were unemployed and/or identified as homemakers, and indicated receipt of services indicating low-income status. Half reported not having health insurance. The top four cancer-related needs or concerns were: Information, Concern for another person, Cost/health insurance, and Fears. Recognizing the centrality of the family in addressing cancer allows for a wider view of the disease and the needs that arise during and after treatment. Key rehabilitation strategies appropriate for intervening with co-survivors of cancer include assessing and building upon strengths and abilities and making culturally-respectful cancer-related information and support accessible.

  6. Hydroxyurea for sickle cell anemia: What have we learned and what questions still remain?

    Science.gov (United States)

    McGann, Patrick T.; Ware, Russell E.

    2011-01-01

    Purpose of review Sickle cell anemia (SCA) is a well-characterized severe hematological disorder with substantial morbidity and early mortality. Hydroxyurea is a potent inducer of fetal hemoglobin, and evidence over the past 25 years has documented its laboratory and clinical efficacy for both adults and children with SCA. Recent findings The Phase III study of hydroxyurea in infants (BABY HUG) has just been completed and preliminary results indicate equivocal benefits for organ protection during the two-year treatment period, but significant benefits for pain, acute chest syndrome, hospitalizations, and transfusions. Three new reports document the benefits of hydroxyurea on reducing mortality in SCA: two adult trials (LaSHS and MSH) and one pediatric study (Brazilian cohort). Recent results from the HUSTLE protocol suggest minimal genotoxicity or carcinogenicity with long-term hydroxyurea exposure. Summary The potential utility of hydroxyurea for all patients with SCA is clear and indisputable. With decades of accumulated evidence and documented efficacy with an acceptable long-term safety profile, it is time to consider hydroxyurea treatment the standard of care for all young patients with SCA. Exporting our knowledge and experience with hydroxyurea to developing nations with large medical burdens from SCA can help relieve global suffering from this condition. PMID:21372708

  7. HIV/AIDS: Knowledge, attitudes and practices among adolescents in Nimule, South Sudan

    Directory of Open Access Journals (Sweden)

    Michael Bol Jool Dit

    2018-02-01

    Full Text Available Background: HIV is an infectious virus commonly transmitted through body fluids mostly semen and blood. It causes a serious and non-curable disease with grave consequences especially in sub-Saharan Africa. In South Sudan the prevalence rate of HIV was estimated at 2.6% in 2016. The treatment options are scarce and educational programs limited. This is of great concern since limited knowledge and awareness of HIV is a major risk factor particularly, among young people. Method: A cross-sectional survey using self-administered questionnaires among adolescents was carried out in November 2016. Results: Sixty-five students participated in the study. In general they had good knowledge about HIV/AIDS with the majority having heard of HIV. Majority stated that HIV spreads through sex (82%, blood transfusion (95%, and from mother to child during pregnancy and delivery (66%. Several misconceptions were present with 43% responding that HIV can be transmitted through mosquito bites and 18% stating that the virus can be spread through shaking hands, hugging and living in the same house. Conclusion: Though the respondents showed fair knowledge about HIV/AIDS, there are still some areas in which they lack knowledge especially regarding spread of the disease and practice. More information about HIV/AIDS and sexual education should be made available.

  8. Proxies of Tropical Cyclone Isotope Spikes in Precipitation: Landfall Site Selection

    Science.gov (United States)

    Lawrence, J. R.; Maddocks, R.

    2011-12-01

    2010 rain from Hurricane Alex, Tropical Depression 2 and Tropical Storm Hermine flooded ephemeral ponds in south Texas. Isotopic analysis of water and fossil Ostracoda from ephemeral ponds in south Texas is planned. Cores (50 cm in length) were taken in one of these ponds where living Ostracoda were found and collected.

  9. Current status of cold fusion

    International Nuclear Information System (INIS)

    Tsarev, V.A.

    1992-01-01

    This paper reports that the term cold fusion (CF) was known up to March 1989 as the synonym of muon-catalyzed fusion, suggested by A.D. Sakharov more than 40 years ago. Broad use of this term for the last two years is associated with other kind of phenomena: fusion at ambient room temperature of nuclei of hydrogen isotopes embedded into crystal lattice. Nowadays only few remember the unbelievable resonance in the whole world, caused by the first claims of CF from Utah and associated with hopes of a simple and ecologically safe solution to the energy problems confronting humanity. The range of the interest reflected also the receptivity of our society for scientific ideas and wide development of telecommunication media. Extraordinary simplicity of CF experiments (in sharp contrast with hug complexity and high cost of thermonuclear researches) stimulated fast involvement of a large number of specialists of various profiles. Participation of small groups and even individual enthusiasts disposing of only simplest physical and chemical equipment became possible. Figuratively speaking, everybody with a pair of strong hands and a spade had a chance to find his nugget of gold in this Klondike. As a result: passion, rush and a very nonuniform composition of participants in this race for cold fusion, far from being all property prepared and having sense of responsibility

  10. Loss of yeast peroxiredoxin Tsa1p induces genome instability through activation of the DNA damage checkpoint and elevation of dNTP levels.

    Directory of Open Access Journals (Sweden)

    Hei-Man Vincent Tang

    2009-10-01

    Full Text Available Peroxiredoxins are a family of antioxidant enzymes critically involved in cellular defense and signaling. Particularly, yeast peroxiredoxin Tsa1p is thought to play a role in the maintenance of genome integrity, but the underlying mechanism is not understood. In this study, we took a genetic approach to investigate the cause of genome instability in tsa1Delta cells. Strong genetic interactions of TSA1 with DNA damage checkpoint components DUN1, SML1, and CRT1 were found when mutant cells were analyzed for either sensitivity to DNA damage or rate of spontaneous base substitutions. An elevation in intracellular dNTP production was observed in tsa1Delta cells. This was associated with constitutive activation of the DNA damage checkpoint as indicated by phosphorylation of Rad9/Rad53p, reduced steady-state amount of Sml1p, and induction of RNR and HUG1 genes. In addition, defects in the DNA damage checkpoint did not modulate intracellular level of reactive oxygen species, but suppressed the mutator phenotype of tsa1Delta cells. On the contrary, overexpression of RNR1 exacerbated this phenotype by increasing dNTP levels. Taken together, our findings uncover a new role of TSA1 in preventing the overproduction of dNTPs, which is a root cause of genome instability.

  11. VizieR Online Data Catalog: CANDELS multiwavelength catalog (Galametz+, 2013)

    Science.gov (United States)

    Galametz, A.; Grazian, A.; Fontana, A.; Ferguson, H. C.; Ashby, M. L. N.; Barro, G.; Castellano, M.; Dahlen, T.; Donley, J. L.; Faber, S. M.; Grogin, N.; Guo, Y.; Huang, K.-H.; Kocevski, D. D.; Koekemoer, A. M.; Lee, K.-S.; McGrath, E. J.; Peth, M.; Willner, S. P.; Almaini, O.; Cooper, M.; Cooray, A.; Conselice, C. J.; Dickinson, M.; Dunlop, J. S.; Fazio, G. G.; Foucaud, S.; Gardner, J. P.; Giavalisco, M.; Hathi, N. P.; Hartley, W. G.; Koo, D. C.; Lai, K.; de Mello, D. F.; McLure, R. J.; Lucas, R. A.; Paris, D.; Pentericci, L.; Santini, P.; Simpson, C.; Sommariva, V.; Targett, T.; Weiner, B. J.; Wuyts, S.; CANDELS Team

    2013-06-01

    The present multiwavelength catalog is based on public data in the CANDELS UDS field (J2000 position: 02:17:37.5-05:12:00) located within the original UDS field. It includes: * CANDELS HST/ACS (F606W, F814W) and HST/WFC3 (F125W, F160W); Grogin et al. 2011ApJS..197...35G, Koekemoer et al. 2011ApJS..197...36K. * CFHT U-band (UKIDSS; Almaini et al. in prep.), * SUBARU B, V, Rc, i', z' (SXDS; Furusawa et al. 2008, Cat. J/ApJS/176/1) * VLT/HAWK-I Y and Ks bands (HUGS; Fontana et al. in prep.) * UKIRT/WFCam J, H, K (UKIDSS DR8; Almaini et al. in prep.) * Spitzer/IRAC SEDS 3.6 and 4.5um (SEDS; Ashby et al. 2013ApJ...769...80A) * Spitzer/IRAC SpUDS 5.8, 8.0um (PI: J. Dunlop). The catalog is F160W-selected and contains 35932 sources over an area of 201.7 square arcmin and includes radio and X-ray detected sources and spectroscopic redshifts available for 210 sources. The full official CANDELS UDS catalog (which contains some extra columns including additional SExtractor parameters derived from the F160W image) can be found on the CANDELS website at: http://candels.ucolick.org/data_access/UDS.html (1 data file).

  12. The effect of spouses' educational classes held for primiparous women referring to Hajar hospital on their quality of life and pregnancy outcomes.

    Science.gov (United States)

    Dehcheshmeh, Faranak Safdari; Salehian, Tahmineh; Parvin, Neda

    2014-02-01

    With regard to the importance of quality of life in pregnant women, the present study aimed to determine the effect of spouses' educational classes held for primaparous women referring to Hajar hospital on women's quality of life and pregnancy outcomes. This clinical trial was conducted from September 2011 to June 2012 in the clinic of the Hajar university center in Shahrekord. Eligible primiparous women who registered for physiologic delivery educational classes were randomly assigned to study (n = 31) and control (n = 27) groups. In the control group, eight physiologic delivery educational sessions were held. In the study group, in addition to attendance of pregnant women, their husbands also attended the third and the eighth sessions of these classes. Women's quality of life was investigated with SF36 questionnaire and pregnancy outcomes after delivery were investigated. Data were analyzed by t-test and Chi-square test. Before intervention, there was no significant difference between scores of quality of life and demographic characteristics (P > 0.05). After intervention, there was a significant difference only in the dimensions of mental health, hugging time, kissing, and breast feeding between the study and control groups (P 0.05). Educational classes held for the pregnant women's husbands during pregnancy can be efficient in promotion of pregnant women's quality of life, especially in improving their mental health.

  13. Newly recognized turbidity current structure can explain prolonged flushing of submarine canyons.

    Science.gov (United States)

    Azpiroz-Zabala, Maria; Cartigny, Matthieu J B; Talling, Peter J; Parsons, Daniel R; Sumner, Esther J; Clare, Michael A; Simmons, Stephen M; Cooper, Cortis; Pope, Ed L

    2017-10-01

    Seabed-hugging flows called turbidity currents are the volumetrically most important process transporting sediment across our planet and form its largest sediment accumulations. We seek to understand the internal structure and behavior of turbidity currents by reanalyzing the most detailed direct measurements yet of velocities and densities within oceanic turbidity currents, obtained from weeklong flows in the Congo Canyon. We provide a new model for turbidity current structure that can explain why these are far more prolonged than all previously monitored oceanic turbidity currents, which lasted for only hours or minutes at other locations. The observed Congo Canyon flows consist of a short-lived zone of fast and dense fluid at their front, which outruns the slower moving body of the flow. We propose that the sustained duration of these turbidity currents results from flow stretching and that this stretching is characteristic of mud-rich turbidity current systems. The lack of stretching in previously monitored flows is attributed to coarser sediment that settles out from the body more rapidly. These prolonged seafloor flows rival the discharge of the Congo River and carry ~2% of the terrestrial organic carbon buried globally in the oceans each year through a single submarine canyon. Thus, this new structure explains sustained flushing of globally important amounts of sediment, organic carbon, nutrients, and fresh water into the deep ocean.

  14. THE WAY TO THE SELF: THE NOVEL «STEPPENWOLF» THROUGH THE LENS OF JUNGIAN PROCESS OF INDIVIDUATION

    Directory of Open Access Journals (Sweden)

    Tetiana V. Danylova

    2015-05-01

    Full Text Available Purpose. This paper aims to analyze the life journey of Harry Haller, protagonist of H. Hesse’s novel «Steppenwolf», in the context of Jungian process of individuation. Methodology. The author has used C.G. Jung’s theory of archetypes, along with hermeneutical methodology. Theoretical basis and results. «Steppenwolf» is the story of a man who is dogged by controversy: he feels himself to be a human and a wolf at the same time. Harry Haller learns from the «Treatise on the Steppenwolf» that he has more than two natures. Actually, he consists of hundreds and thousands of them. This idea is based on Jung’s concept of the collective unconscious. And the very novel «Steppenwolf» brightly illustrates Jung’s individuation process. Harry Haller’s mission is to overcome opposition between his social cultural «I» and Shadow (Steppenwolf, to recognize and accept his Anima (Hermine, to understand the mystery of the identity of Pablo, who embodies chthonic depths, and Mozart, who represents sublime spirituality, that is, to comprehend his own Self. Scientific novelty. In the novel, the human nature is depicted as the eternal struggle and eternal unity of two polarities. Individuals have to realize this unity on their way to the Self. Recognizing, confronting and assimilating the Ego, Anima/Animus, Shadow into the larger realm of the Self, one achieves a new level of consciousness. However, this is a never-ending process, unattainable ideal. At the end of the novel, Harry Haller failed to cope with this challenge. It seems that he has remained at the same point, where we had met him. However, nothing was impossible − everything was just beginning. Conclusions. The questions raised by Jungian analysis push us beyond our limits to the great alchemical mystery − the wholeness of our own souls. For the salvation of humankind as a whole and every single human in our world full of conflicts and violence, we all need to

  15. Indicators for Research Performance in the Humanities? The Scholars’ View on Research Quality and Indicators

    Energy Technology Data Exchange (ETDEWEB)

    Ochsner, M.; Hug, S.E.

    2016-07-01

    In this paper, we present indicators for research quality in the humanities collected in our previous work (Ochsner, Hug, & Daniel, 2012). We focus on how these indicators are accepted by humanities scholars. We also investigate differences between different subgroups of the humanities scholars we surveyed with regard to their preferences for such indicators. We address the theme of the conference (‘peripheries frontiers and beyond’) regarding two notions of (scientometric) periphery: First, we investigate indicators for research quality in the humanities, a field where there is a lack on knowledge on how to assess or even measure research quality, in fact, there is a quite broad consensus that (evaluative) bibliometrics cannot be readily applied in the humanities (Hicks, 2004; Nederhof, 2006). Second, we fully cover three humanities disciplines at Swiss universities and member universities of the League of European Research Universities (LERU). Scholars are a neglected stakeholder when it comes to the design of research assessment procedures or the selection of research indicators. However, they are directly affected, they know best what research quality in their field is and what impact the use of certain indicators could have on their research practices. The paper is structured as follows: first, we present the background for selecting indicators for research quality. This is followed by a description of our analysis methods and the presentation of the results. We finally discuss the results with regard to their use in research evaluation. (Author)

  16. Modifying cochlear implant design: advantages of placing a return electrode in the modiolus.

    Science.gov (United States)

    Ho, Steven Y; Wiet, Richard J; Richter, Claus-Peter

    2004-07-01

    A modiolar return electrode significantly increases the current flow across spiral ganglion cells into the modiolus, and may decrease the cochlear implant's power requirements. Ideal cochlear implants should maximize current flow into the modiolus to stimulate auditory neurons. Previous efforts to facilitate current flow through the modiolus included the fabrication and use of precurved electrodes designed to "hug" the modiolus and silastic positioners designed to place the electrodes closer to the modiolus. In contrast to earlier efforts, this study explores the effects of return electrode placement on current distributions in the modiolus. The effects of return electrode positioning on current flow in the modiolus were studied in a Plexiglas model of the cochlea. Results of model measurements were confirmed by measurements in the modiolus of human temporal bones. The return electrode was placed either within the modiolus, or remotely, outside the temporal bone, simulating contemporary cochlear implant configurations using monopolar stimulation. Cochlear model results clearly show that modiolar current amplitudes can be influenced significantly by the location of the return electrode, being larger when placed into the modiolus. Temporal bone data show similar findings. Voltages recorded in the modiolus are, on average, 2.8 times higher with the return electrode in the modiolus compared with return electrode locations outside the temporal bone. Placing a cochlear implant's return electrode in the modiolus should significantly reduce its power consumption. Reducing power requirements should lead to improved efficiency, safer long-term use, and longer device life.

  17. Microarray analysis of HIV resistant female sex workers reveal a gene expression signature pattern reminiscent of a lowered immune activation state.

    Directory of Open Access Journals (Sweden)

    Elijah M Songok

    Full Text Available To identify novel biomarkers for HIV-1 resistance, including pathways that may be critical in anti-HIV-1 vaccine design, we carried out a gene expression analysis on blood samples obtained from HIV-1 highly exposed seronegatives (HESN from a commercial sex worker cohort in Nairobi and compared their profiles to HIV-1 negative controls. Whole blood samples were collected from 43 HIV-1 resistant sex workers and a similar number of controls. Total RNA was extracted and hybridized to the Affymetrix HUG 133 Plus 2.0 micro arrays (Affymetrix, Santa Clara CA. Output data was analysed through ArrayAssist software (Agilent, San Jose CA. More than 2,274 probe sets were differentially expressed in the HESN as compared to the control group (fold change ≥1.3; p value ≤0.0001, FDR <0.05. Unsupervised hierarchical clustering of the differentially expressed genes readily distinguished HESNs from controls. Pathway analysis through the KEGG signaling database revealed a majority of the impacted pathways (13 of 15, 87% had genes that were significantly down regulated. The most down expressed pathways were glycolysis/gluconeogenesis, pentose phosphate, phosphatidyl inositol, natural killer cell cytotoxicity and T-cell receptor signaling. Ribosomal protein synthesis and tight junction genes were up regulated. We infer that the hallmark of HIV-1 resistance is down regulation of genes in key signaling pathways that HIV-1 depends on for infection.

  18. Challenges and opportunities: using a science-based video game in secondary school settings

    Science.gov (United States)

    Muehrer, Rachel; Jenson, Jennifer; Friedberg, Jeremy; Husain, Nicole

    2012-12-01

    Simulations and games are not new artifacts to the study of science in secondary school settings (Hug, Kriajcik and Marx 2005), however teachers remain skeptical as to their value, use and appropriateness (Rice 2006). The difficulty is not only the design and development of effective play environments that produce measurable changes in knowledge and/or understanding, but also in their on-the-ground use (Jaipal and Figg 2010). This paper reports on the use of a science-focused video game in five very different secondary school settings in Ontario, Canada. A mixed-methods approach was used in the study, and included data gathered on general gameplay habits and technology use, as well as informal interviews with teachers and students who played the game. In total, 161 participants played a series of games focused on the "life of a plant", and were given both a pre and post quiz to determine if the game helped them retain and/or change what they knew about scientific processes like plant cell anatomy and photosynthesis. Participants showed statistically significant improvement on quizzes that were taken after playing the game for approximately one-hour sessions, despite difficulties in some cases both accessing and playing the game for the full hour. Our findings also reveal the ongoing challenges in making use of technology in a variety of school sessions, even when using a browser-based game, that demanded very little other than a reliable internet connection.

  19. Should we 'hug a hoodie'? Protocol for a systematic review and meta-analysis of interventions with young people not in employment, education or training (so-called NEETs).

    Science.gov (United States)

    Oliver, Emily J; Mawn, Lauren; Stain, Helen J; Bambra, Clare L; Torgerson, Carole; Oliver, Anita; Bridle, Chris

    2014-07-07

    Whilst the majority of young people succeed in education and make a positive transition to the world of work and adult life, recent statistics identify that youth comprise 40% of the world's unemployed, equating to nearly 75 million individuals. These numbers are associated with both decreased economic activity and adverse well-being, with accompanying social, health and financial costs. As a result, a wide range of providers have implemented interventions targeting this population; however, their relative effectiveness is unknown. This is exacerbated by a diverse literature base, the delivery of provision and policy across multiple sectors and disparate approaches to programme evaluation. We will undertake a systematic review of interventions targeting youth not in employment, education or training (NEET) populations. Only randomised and non-randomised controlled trials will be included. The objectives of the review will be to: (i) systematically review, synthesise and quality appraise experimental evidence on the effects of interventions with NEET young people, (ii) estimate effects on current NEET status, well-being and other relevant psychological and behavioural outcomes, (iii) investigate potential variation in intervention effects among sub-groups stratified by pre-trial duration of current status, socioeconomic status, gender, sub-classifications of NEET individuals and intervention components (e.g. type, frequency, duration, provider and setting) and (iv) assess the robustness of results in separate sensitivity analyses that exclude studies with higher risk of bias (e.g. in terms of study quality) or follow-up length. A rigorous literature search of English language publications post-1990 will be conducted using the following electronic databases: Medline, Embase, PsycINFO, ERIC, EPPI-Centre (Bibliomap), Social Science Citation Index, British Education Index, Conference Proceedings Index, Dissertation Abstracts, Popline and grey literature collections (e.g. GLADNET). These database searches will be supplemented with hand searching, requests for unpublished literature and website searches. A report and executive summary will be developed by the research team with input from consultant stakeholders to aid translation of the findings into practice. The research will be disseminated at national and international conferences and submitted for peer-reviewed publication. PROSPERO CRD42014007535.

  20. The impact of dementia and mild memory impairment (MMI) on intimacy and sexuality in spousal relationships.

    Science.gov (United States)

    Davies, Helen D; Newkirk, Lori A; Pitts, Christiane B; Coughlin, Christine A; Sridhar, Sneha B; Zeiss, L McKenzie; Zeiss, Antonette M

    2010-06-01

    Sexuality and intimacy in couples in which one partner is affected by dementia has been widely researched. Few studies have explored these issues in couples where one partner is affected by mild memory impairment (MMI) or mild cognitive impairment (MCI). The objectives of this study were to (1) identify and contrast issues of intimacy and sexuality that spousal caregivers of persons with MMI and dementia may experience, and (2) identify future lines of research in this population. Fourteen dementia and nine MMI spousal caregivers participated in focus groups conducted between 2008 and 2009 at the Stanford/VA Alzheimer's Research Center. Content analyses were conducted to identify themes. Five themes emerged: communication, marital cohesion, affectional expression, caregiver burden, and ambiguity concerning the future of the relationship. Dementia caregivers reported more difficulties with communication, cohesion, and perceptions of increased burden than their MMI counterparts. Both groups indicated reduced sexual expression due to physical limitations; substitute activities including hand-holding, massaging, and hugging were noted. Both groups reported difficulty anticipating the future of the relationship due to present stressors. While dementia caregivers could consider future romantic relationships with others, MMI caregivers were primarily able to consider future relationships only for companionship and emotional intimacy. Early therapeutic interventions may assist couples in modifying activities, behaviors, and expectations about the future of the relationship. Such modifications may help maintain relationship satisfaction, decrease burden, preserve quality of life, and delay time-to-placement. Extending time-to-placement could have cost savings implications for families and the healthcare system.

  1. Biochemical characterization of legume seeds as ingredients in animal feed

    Energy Technology Data Exchange (ETDEWEB)

    Martín-Pedrosa, M.; Varela, A.; Guillamon, E.; Cabellos, B.; Burbano, C.; Gomez-Fernandez, J.; Mercado, E. de; Gomez-Izquierdo, E.; Cuadrado, C.; Muzquiz, M.

    2016-11-01

    The current European protein deficit is estimated as high as 70% of present needs. Because of the high protein content of their seeds, grain legumes are attractive candidates for lowering the deficiency in plant protein production. The objective of this work was to identify new sources of vegetable protein that would reduce our high dependence of soy, the main source of protein in the manufacture of feedstuffs. To achieve this goal, we determined the proximate composition, the bioactive components, as well as the antinutritional factors present in the studied seeds. In general, the protein, fat and carbohydrates content of legume seeds studied were within the limits found in the literature. The bioactive compounds detected in all the seeds were α-galactosides, myoinositol phosphates, protease inhibitors and phenols. IP6 (phytic acid) was the main inositol phosphate form in all the samples. The highest protease inhibitors content was detected in both Lathyrus cicera cultivars. Vicia ervilia and L. cicera cultivars showed low haemagglutinating activity (20.4 HU/g). The γ-glutamyl-S-ethenyl-cysteine content in Vicia narbonensis was around 16.0 mg/g. Both L. cicera varieties presented similar β-N-oxalyl-L-α, β-diaminopropionic acid content (0.80 mg/g). The two V. ervilia varieties showed high canavanine concentration (1.93-5.28 mg/g). Vicine was only detected in V. narbonensis cultivars (0.3 mg/g). The biochemical characterization carried out in this study allows us to know the limits of inclusion of these minor crop seeds in feed formulations in order to replace the soybean. (Author)

  2. Research reactors: design, safety requirements and applications

    International Nuclear Information System (INIS)

    Hassan, Abobaker Mohammed Rahmtalla

    2014-09-01

    There are two types of reactors: research reactors or power reactors. The difference between the research reactor and energy reactor is that the research reactor has working temperature and fuel less than the power reactor. The research reactors cooling uses light or heavy water and also research reactors need reflector of graphite or beryllium to reduce the loss of neutrons from the reactor core. Research reactors are used for research training as well as testing of materials and the production of radioisotopes for medical uses and for industrial application. The difference is also that the research reactor smaller in terms of capacity than that of power plant. Research reactors produce radioactive isotopes are not used for energy production, the power plant generates electrical energy. In the world there are more than 284 reactor research in 56 countries, operates as source of neutron for scientific research. Among the incidents related to nuclear reactors leak radiation partial reactor which took place in three mile island nuclear near pennsylvania in 1979, due to result of the loss of control of the fission reaction, which led to the explosion emitting hug amounts of radiation. However, there was control of radiation inside the building, and so no occurred then, another accident that lead to radiation leakage similar in nuclear power plant Chernobyl in Russia in 1986, has led to deaths of 4000 people and exposing hundreds of thousands to radiation, and can continue to be effect of harmful radiation to affect future generations. (author)

  3. Brief Report: Un Abrazo Para la Familia: Providing Low-Income Hispanics with Education and Skills in Coping with Breast Cancer and Caregiving

    Science.gov (United States)

    Badger, Terry A.; Curran, Melissa A.; Koerner, Susan Silverberg; Larkey, Linda K.; Weihs, Karen L.; Verdugo, Lorena; García, Francisco A. R.

    2012-01-01

    Objective Un Abrazo Para La Familia [A Hug for the Family] is an intervention designed to increase the accessibility of cancer information to low-income and medically underserved co-survivors of cancer. Co-survivors are family members or friends of an individual diagnosed with cancer. Our goal was to increase socio-emotional support for co-survivors, and improve skills in coping with cancer. The purpose of our pilot study was to explore the effectiveness of the intervention in increasing cancer knowledge and self-efficacy among co-survivors. Methods Un Abrazo consisted of three one-hour sessions, in either Spanish or English. Sessions were delivered by a trained promotora [community health worker], in partnership with a counselor. Sixty participants completed measures of cancer knowledge and self-efficacy preceding (pre-test) and following the intervention (post-test). Results From pre- to post-test, the percentage of questions answered correctly about cancer knowledge increased (p < .001), as did ratings of self-efficacy (p < .001). Decreases were seen in “Do not know” responses for cancer knowledge (p < .01), with a negative correlation between number of “Do not knows” on cancer knowledge at pre-test and ratings of self-efficacy at pre-test (r = −.47, p < .01). Conclusions When provided an accessible format, co-survivors of cancer from underserved populations increase their cancer knowledge and self-efficacy. This is notable because research indicates that family members and friends with increased cancer knowledge assume more active involvement in the cancer care of their loved ones. PMID:22140003

  4. Un Abrazo Para La Familia: providing low-income Hispanics with education and skills in coping with breast cancer and caregiving.

    Science.gov (United States)

    Marshall, Catherine A; Badger, Terry A; Curran, Melissa A; Koerner, Susan Silverberg; Larkey, Linda K; Weihs, Karen L; Verdugo, Lorena; García, Francisco A R

    2013-02-01

    Un Abrazo Para La Familia (A Hug for the Family) is an intervention designed to increase the accessibility of cancer information to low-income and medically underserved co-survivors of cancer. Co-survivors are family members or friends of an individual diagnosed with cancer. Our goal was to increase socio-emotional support for these co-survivors and improve skills in coping with cancer. The purpose of our pilot study was to explore the effectiveness of the intervention in increasing cancer knowledge and self-efficacy among co-survivors. Un Abrazo consisted of three one-hour sessions, in either Spanish or English. Sessions were delivered by a trained promotora (community health worker), in partnership with a counselor. Sixty participants completed measures of cancer knowledge and self-efficacy preceding (pre-test) and following the intervention (post-test). From pre-test to post-test, the percentage of questions answered correctly about cancer knowledge increased (p < 0.001), as did ratings of self-efficacy (p < 0.001). Decreases were seen in 'Do not know' responses for cancer knowledge (p < 0.01), with a negative correlation between number of 'Do not knows' on cancer knowledge at pre-test and ratings of self-efficacy at pre-test (r = -0.47, p < 0.01). When provided an accessible format, co-survivors of cancer from underserved populations increase their cancer knowledge and self-efficacy. This is notable because research indicates that family members and friends with increased cancer knowledge assume more active involvement in the cancer care of their loved ones. Copyright © 2011 John Wiley & Sons, Ltd.

  5. Women and AIDS.

    Science.gov (United States)

    Seghal, P N

    1991-04-01

    In this article, Dr. P.N. Sehgal, former director of the National Institute of Communicable Diseases in Delhi, explains the steps that women need to take to protect themselves against AIDS and discusses some issues facing women who have already contracted the disease. Because of women's lack of status in the family and society, it is harder for them to ensure their safety. Women based at home often lack information on AIDS, and those women who are informed sometimes depend on their male partner for financial support, which means that they are forced to engage in unsafe sexual practices. Safer sexual practices can reduce the risk for women. Though varying in degree of safety, some safer practices include: monogamous relationships between uninfected partners; the use of condoms for all types of sexual intercourse; non-penetrative sex practices (hugging, kissing, masturbating); reducing the number of sexual partners; avoiding sex when either of the partners has open sores or any STD. Pregnant women should also receive information concerning AIDS, including: a baby born from an HIV-infected mother has a 20-40% of being infected; the risk of transmission is higher when the mother already shows signs of AIDS; and an infected baby may die within the first few years of life. the HIV transmission may occur prepartum or during birth itself, but the risk of transmission from breastfeeding is extremely low. Dr. Sehgal stresses the need for privacy and confidentiality when dealing with carriers of the disease or when carrying out HIV testing. Above all, the rights of HIV-infected people must be protected.

  6. The Effect of Scala Tympani Morphology on Basilar Membrane Contact With a Straight Electrode Array: A Human Temporal Bone Study.

    Science.gov (United States)

    Verberne, Juul; Risi, Frank; Campbell, Luke; Chambers, Scott; O'Leary, Stephen

    2017-01-01

    Scala tympani morphology influences the insertion dynamics and intra-scalar position of straight electrode arrays. Hearing preservation is the goal of cochlear implantation with current thin straight electrode arrays. These hug the lateral wall, facilitating full, atraumatic insertions. However, most studies still report some postoperative hearing loss. This study explores the influence of scala tympani morphology on array position relative to the basilar membrane and its possible contribution to postoperative hearing loss. Twenty-six fresh-frozen human temporal bones implanted with a straight electrode array were three-dimensionally reconstructed from micro-photographic histological sections. Insertion depth and the proximity between the array and basilar membrane were recorded. Lateral wall shape was quantified as a curvature ratio. Insertion depths ranged from 233 to 470 degrees. The mean first point of contact between the array and basilar membrane was 185 degrees; arrays tended to remain in contact with the membrane after first contacting it. Eighty-nine and 93% of arrays that reached the upper basal (>240-360 degrees) and second (>360-720 degrees) turns respectively contacted the basilar membrane in these regions. Scalar wall curvature ratio decreased significantly (the wall became steeper) from the basal to second turns. This shift correlated with a reduced distance between the array and basilar membrane. Scala tympani morphology influences the insertion dynamics and intra-scalar position of a straight electrode array. In addition to gross trauma of cochlear structures, contact between the array and basilar membrane and how this impacts membrane function should be considered in hearing preservation cases.

  7. Behavioral correlates of the distributed coding of spatial context.

    Science.gov (United States)

    Anderson, Michael I; Killing, Sarah; Morris, Caitlin; O'Donoghue, Alan; Onyiagha, Dikennam; Stevenson, Rosemary; Verriotis, Madeleine; Jeffery, Kathryn J

    2006-01-01

    Hippocampal place cells respond heterogeneously to elemental changes of a compound spatial context, suggesting that they form a distributed code of context, whereby context information is shared across a population of neurons. The question arises as to what this distributed code might be useful for. The present study explored two possibilities: one, that it allows contexts with common elements to be disambiguated, and the other, that it allows a given context to be associated with more than one outcome. We used two naturalistic measures of context processing in rats, rearing and thigmotaxis (boundary-hugging), to explore how rats responded to contextual novelty and to relate this to the behavior of place cells. In experiment 1, rats showed dishabituation of rearing to a novel reconfiguration of familiar context elements, suggesting that they perceived the reconfiguration as novel, a behavior that parallels that of place cells in a similar situation. In experiment 2, rats were trained in a place preference task on an open-field arena. A change in the arena context triggered renewed thigmotaxis, and yet navigation continued unimpaired, indicating simultaneous representation of both the altered contextual and constant spatial cues. Place cells similarly exhibited a dual population of responses, consistent with the hypothesis that their activity underlies spatial behavior. Together, these experiments suggest that heterogeneous context encoding (or "partial remapping") by place cells may function to allow the flexible assignment of associations to contexts, a faculty that could be useful in episodic memory encoding. Copyright (c) 2006 Wiley-Liss, Inc.

  8. Examining associations between sexual behaviours and quality of life in older adults.

    Science.gov (United States)

    Flynn, Taylor-Jane; Gow, Alan J

    2015-09-01

    while sexual behaviours are potentially important for quality of life in older adults, they are under-researched. The current study examined associations between frequency and importance of sexual behaviours and quality of life in older adults. one hundred and thirty-three participants (mean 74 years, SD = 7.1) provided information about the frequency with which they participated in six sexual behaviours and the perceived importance of these: touching/holding hands, embracing/hugging, kissing, mutual stroking, masturbating and intercourse. Participants also completed the WHO Quality of Life scale, providing an overall quality of life score, in addition to the domains of physical health, psychological health, social relationships and environment. Participants provided information on their marital status, living arrangements and self-reported health. both the frequency and importance of sexual behaviours were moderately positively correlated with quality of life (r = 0.52 and 0.47, respectively, both P sexual behaviours was a significant predictor of quality of life in the social relationships domain (β = 0.225, P sexual behaviours was associated with the psychological domain (β = 0.151, P ageing trends, a broader understanding of the factors that influence quality of life in older adults is increasingly important. The current findings suggest that aspects of sexual behaviour and quality of life were positively associated. Researchers are encouraged to consider aspects of sex and sexuality when exploring determinants of well-being in later life. © The Author 2015. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  9. Evaluation of the results from arthroscopic tenodesis of the long head of the biceps brachii on the tendon of the subscapularis muscle

    Directory of Open Access Journals (Sweden)

    Marcelo Baggio

    2016-04-01

    Full Text Available OBJECTIVES: The aim of this study was to evaluate the results from arthroscopic tenodesis of the long head of the biceps brachii (LHBB on the tendon of the subscapularis muscle, with regard to the presence of pain, subscapularis lesion, presence of Popeye's sign and patient satisfaction. METHODS: A prospective cohort study was conducted on 32 patients with LHBB lesions, through preoperative interviews and physical examinations, which were repeated six months after the operation. The main variables studied were the belly press, bear hug and lift-off tests, Popeye's sign, anterior pain and satisfaction. The data were entered into Epi Info 3.5.4 and SPSS 18.0. In order to investigate the variables of interest, the chi-square, Student t and Kruskal-Wallis tests were used. The confidence interval was 95% and p values less than 0.05 were taken to be statistically significant. RESULTS: 32 patients of median age 57.5 years were evaluated. Anterior pain was reported by one interviewee after the operation. The tests for evaluating subscapularis lesions did not show any damage to this musculature after the surgery. Popeye's sign was negative in all the patients. The patient satisfaction rate reached 90.6% of the interviewees. CONCLUSION: This study showed that the new surgical technique described here presented excellent performance, without any subscapularis lesion and without identifying Popeye's sign. Only 3.1% of the patients had complaints of residual pain. The high level of satisfaction among the patients after the surgery confirms the results presented.

  10. Storm water detention tanks in Barcelona; Los depositos de retencion de aguas pluviales de Barcelona: un nuevo enfoque en la lucha contra las inundaciones y la proteccion medioambiental

    Energy Technology Data Exchange (ETDEWEB)

    Pere Malgrat i Bregolat, P.; Verdejo, J. M.; Vilalta i Cambra, A.

    2004-07-01

    Storm water detention tanks are being implemented at first as a solution to the urban flooding problem and afterwards a second function was added to reduce the pollution of the sewerage waters before its overflow to the receiving bodies because these spills can contribute with up to 50% of the total pollution spilled. These solutions are often cheaper and have less impact on the urban activities than the classical solutions such as trunk sewers. In Spain, Barcelona was the first city to build this tanks to avoid flooding and also to reduce the contamination to the receiving waters, with a total volume of 492.200 m''3, operated by Clavegueram de Barcelona (Clabsa). These works have meant a big improvement in the management of the wet weather flows in Barcelona. These tanks have increased the capacity of the sewerage system and decreased the combined sewer overflows to the receiving waters (Besos river and Mediterranean sea). Another advantage is the protection of WWTP against flow variations. The environmental improvement achieved with the tanks is so hug that can even reduce the contamination spilled to the receiving waters around 30% and avoid the destruction of some ecosystems. Also, the contaminated sediments trapped in the detention tank are sen to to the WWTP so the don't reach the receiving waters. Also. the urban space close to the relieving waters are becoming more appreciated for leisure so the recovery and protection of these waters is a must. (Author)

  11. Immunologic effects of hydroxyurea in sickle cell anemia.

    Science.gov (United States)

    Lederman, Howard M; Connolly, Margaret A; Kalpatthi, Ram; Ware, Russell E; Wang, Winfred C; Luchtman-Jones, Lori; Waclawiw, Myron; Goldsmith, Jonathan C; Swift, Andrea; Casella, James F

    2014-10-01

    Susceptibility to encapsulated bacteria is well known in sickle cell disease (SCD). Hydroxyurea use is common in adults and children with SCD, but little is known about hydroxyurea's effects on immune function in SCD. Because hydroxyurea inhibits ribonucleotide reductase, causing cell cycle arrest at the G1-S interface, we postulated that hydroxyurea might delay transition from naive to memory T cells, with inhibition of immunologic maturation and vaccine responses. T-cell subsets, naive and memory T cells, and antibody responses to pneumococcal and measles, mumps, and rubella vaccines were measured among participants in a multicenter, randomized, double-blind, placebo-controlled trial of hydroxyurea in infants and young children with SCD (BABY HUG). Compared with placebo, hydroxyurea treatment resulted in significantly lower total lymphocyte, CD4, and memory T-cell counts; however, these numbers were still within the range of historical healthy controls. Antibody responses to pneumococcal vaccination were not affected, but a delay in achieving protective measles antibody levels occurred in the hydroxyurea group. Antibody levels to measles, mumps, and rubella showed no differences between groups at exit, indicating that effective immunization can be achieved despite hydroxyurea use. Hydroxyurea does not appear to have significant deleterious effects on the immune function of infants and children with SCD. Additional assessments of lymphocyte parameters of hydroxyurea-treated children may be warranted. No changes in current immunization schedules are recommended; however, for endemic disease or epidemics, adherence to accelerated immunization schedules for the measles, mumps, and rubella vaccine should be reinforced. Copyright © 2014 by the American Academy of Pediatrics.

  12. Framatome, from the nuclear engineering office to the international group

    International Nuclear Information System (INIS)

    Lorin, Philippe

    1995-01-01

    A simple office of studies by its inceptions, Framatome became during 30 years an international and diversified group, a world nuclear leader, as designer-manufacturer, fuel supplier and servicing provider. It asserts itself also as a foreground actor in the industrial equipment and connections. This book not only presents an exciting and capital episode of the history of nuclear energy in France but it demonstrate also how an company with a little bit of chance, a lot of endeavour, a plenty of talent and a huge firmness succeeded in becoming an incontestable reference authority in its sector. Staking on technological choices, although different from the creeds inspiring the French decision makers, Framatome has obtained its first orders ahead other French companies, much more powerful and prestigious at the time. The impressive Framatome evolution is presented along six chapters entitled as follows: 1. Beginning of nuclear power; 2. Technological challenge; 3. Industrial challenge; 4. Sectorial challenge; 5. Management challenge; 6. Future. The following four witness' papers are inserted with in the main text: 1. Beginning of Framatome (by P. Boulin); 2. The difficult choice for the PWR system (by M. Boiteux); 3. Impossibly is not French (by A. Giraud); 4. A fabulous common effort (by M. Hug). The book is addressed to the public at large but aims also at the Company's personnel, both the people witnessing the Company's beginning and the newcomers who should know the social body they have chosen to join and to the effort of which they have to contribute with their inventiveness and dynamism

  13. Asymmetrical color filling-in from the nasal to the temporal side of the blind spot

    Science.gov (United States)

    Li, Hui; Luo, Junxiang; Lu, Yiliang; Kan, Janis; Spillmann, Lothar; Wang, Wei

    2014-01-01

    The physiological blind spot, corresponding to the optic disk in the retina, is a relatively large (6 × 8°) area in the visual field that receives no retinal input. However, we rarely notice the existence of it in daily life. This is because the blind spot fills in with the brightness, color, texture, and motion of the surround. The study of filling-in enables us to better understand the creative nature of the visual system, which generates perceptual information where there is none. Is there any retinotopic rule in the color filling-in of the blind spot? To find out, we used mono-colored and bi-colored annuli hugging the boundary of the blind spot. We found that mono-colored annuli filled in the blind spot uniformly. By contrast, bi-colored annuli, where one half had a given color, while the other half had a different one, filled in the blind spot asymmetrically. Specifically, the color surrounding the nasal half typically filled in about 75% of the blind spot area, whereas the color surrounding the temporal half filled in only about 25%. This asymmetry was dependent on the relative size of the half rings, but not the two colors used, and was absent when the bi-colored annulus was rotated by 90°. Here, the two colors on the upper and lower sides of the blind spot filled in the enclosed area equally. These results suggest that the strength of filling-in decreases with distance from the fovea consistent with the decrease of the cortical magnification factor. PMID:25100977

  14. Morphodynamic Model of Submarine Canyon Incision by Sandblasting

    Science.gov (United States)

    Zhang, L.; Parker, G.; Izumi, N.; Cartigny, M.; Li, T.; Wang, G.

    2017-12-01

    Submarine canyons are carved by turbidity currents under the deep sea. As opposed to subaerial canyons, the relevant processes are not easy to observe directly. Turbidity currents are bottom-hugging sediment gravity flows of that can incise or deposit on the seafloor to create submarine canyons or fans. The triggers of turbidity currents can be storms, edge waves, internal waves, canyon wall sapping, delta failure, breaching and hyperpycnal flows. The formation and evolution mechanisms of submarine canyons are similar to those of subaerial canyons, but have substantial differences. For example, sandblasting, rather than wear due to colliding gravel clasts is more likely to be the mechanism of bedrock incision. Submarine canyons incise downward, and often develop meander bends and levees within the canyon, so defining "fairways". Here we propose a simple model for canyon incision. The starting point of our model is the Macro Roughness Saltation Abrasion Alluviation model of Zhang et al. [2015], designed for bedrock incision by gravel clasts in mixed bedrock-alluvial rivers. We adapt this formulation to consider sandblasting as a means of wear. We use a layer-averaged model for turbidity current dynamics. The current contains a mixture of mud, which helps drive the flow but which does not cause incision, and sand, which is the agent of incision. We show that the model can successfully model channel downcutting, and indeed illustrate the early formation of net incisional cyclic steps, i.e. upstream-migrating undulations on the bed associated with transcritical (in the Froude sense) flow. These steps can be expected to abet the process of incision.

  15. Residents' engagement in everyday activities and its association with thriving in nursing homes.

    Science.gov (United States)

    Björk, Sabine; Lindkvist, Marie; Wimo, Anders; Juthberg, Christina; Bergland, Ådel; Edvardsson, David

    2017-08-01

    To describe the prevalence of everyday activity engagement for older people in nursing homes and the extent to which engagement in everyday activities is associated with thriving. Research into residents' engagement in everyday activities in nursing homes has focused primarily on associations with quality of life and prevention and management of neuropsychiatric symptoms. However, the mere absence of symptoms does not necessarily guarantee experiences of well-being. The concept of thriving encapsulates and explores experiences of well-being in relation to the place where a person lives. A cross-sectional survey. A national survey of 172 Swedish nursing homes (2013-2014). Resident (n = 4831) symptoms, activities and thriving were assessed by staff using a study survey based on established questionnaires. Descriptive statistics, simple and multiple linear regression, and linear stepwise multiple regression were performed. The most commonly occurring everyday activities were receiving hugs and physical touch, talking to relatives/friends and receiving visitors, having conversation with staff not related to care and grooming. The least commonly occurring everyday activities were going to the cinema, participating in an educational program, visiting a restaurant and doing everyday chores. Positive associations were found between activity engagement and thriving, where engagement in an activity program, dressing nicely and spending time with someone the resident likes had the strongest positive association with resident thriving. Engagement in everyday activities can support personhood and thriving and can be conceptualized and implemented as nursing interventions to enable residents to thrive in nursing homes. © 2017 John Wiley & Sons Ltd.

  16. Surf zone entrainment, along-shore transport, and human health implications of pollution from tidal outlets

    Science.gov (United States)

    Grant, S. B.; Kim, J. H.; Jones, B. H.; Jenkins, S. A.; Wasyl, J.; Cudaback, C.

    2005-10-01

    Field experiments and modeling studies were carried out to characterize the surf zone entrainment and along-shore transport of pollution from two tidal outlets that drain into Huntington Beach and Newport Beach, popular public beaches in southern California. The surf zone entrainment and near-shore transport of pollutants from these tidal outlets appears to be controlled by prevailing wave conditions and coastal currents, and fine-scale features of the flow field around the outlets. An analysis of data from dye experiments and fecal indicator bacteria monitoring studies reveals that the along-shore flux of surf zone water is at least 50 to 300 times larger than the cross-shore flux of surf zone water. As a result, pollutants entrained in the surf zone hug the shore, where they travel significant distances parallel to the beach before diluting to extinction. Under the assumption that all surf zone pollution at Huntington Beach originates from two tidal outlets, the Santa Ana River and Talbert Marsh outlets, models of mass and momentum transport in the surf zone approximately capture the observed tidal phasing and magnitude of certain fecal indicator bacteria groups (total coliform) but not others (Escherichia coli and enterococci), implying the existence of multiple sources of, and/or multiple transport pathways for, fecal pollution at this site. The intersection of human recreation and near-shore pollution pathways implies that, from a human health perspective, special care should be taken to reduce the discharge of harmful pollutants from land-side sources of surface water runoff, such as tidal outlets and storm drains.

  17. Biochemical characterization of legume seeds as ingredients in animal feed

    Directory of Open Access Journals (Sweden)

    Mercedes Martín-Pedrosa

    2016-03-01

    Full Text Available The current European protein deficit is estimated as high as 70% of present needs. Because of the high protein content of their seeds, grain legumes are attractive candidates for lowering the deficiency in plant protein production. The objective of this work was to identify new sources of vegetable protein that would reduce our high dependence of soy, the main source of protein in the manufacture of feedstuffs. To achieve this goal, we determined the proximate composition, the bioactive components, as well as the antinutritional factors present in the studied seeds. In general, the protein, fat and carbohydrates content of legume seeds studied were within the limits found in the literature. The bioactive compounds detected in all the seeds were α-galactosides, myoinositol phosphates, protease inhibitors and phenols. IP6 (phytic acid was the main inositol phosphate form in all the samples. The highest protease inhibitors content was detected in both Lathyrus cicera cultivars. Vicia ervilia and L. cicera cultivars showed low haemagglutinating activity (20.4 HU/g. The γ-glutamyl-S-ethenyl-cysteine content in Vicia narbonensis was around 16.0 mg/g. Both L. cicera varieties presented similar β-N-oxalyl-L-α, β-diaminopropionic acid content (0.80 mg/g. The two V. ervilia varieties showed high canavanine concentration (1.93-5.28 mg/g. Vicine was only detected in V. narbonensis cultivars (0.3 mg/g. The biochemical characterization carried out in this study allows us to know the limits of inclusion of these minor crop seeds in feed formulations in order to replace the soybean.

  18. What do Patients Want From Their Radiation Oncologist? Initial Results From a Prospective Trial

    International Nuclear Information System (INIS)

    Bhatnagar, Ajay K.; Land, Stephanie R.; Shogan, Alyson; Rodgers, Edwin E.; Heron, Dwight E.; Flickinger, John C.

    2007-01-01

    Purpose: To assess patients' initial physician preferences using a newly developed instrument. Methods and Materials: A total of 182 patients with a primary diagnosis of prostate, breast, or lung cancer referred for consultation to University of Pittsburgh Cancer Institute Department of Radiation Oncology enrolled in our institutional review board-approved protocol. All patients completed patient preference instrument surveys before meeting their radiation oncologist. Survey responses to 10 statements were categorized into three groups (agree, neutral, or disagree), and the association of survey responses by cancer site was tested with chi-squared tests. Results: Ninety-nine percent of all patients preferred to be addressed by their first name in encounters with their radiation oncologist. There were significant associations of Item 3 (hand holding) with gender (p = 0.039) and education (p = 0.028). The responses to Item 5, a statement that patients would feel uncomfortable if the radiation oncologist offered to hug them at the end of treatment, was significantly associated with disease site (p < 0.0001). Further analysis was performed for Item 5 and revealed that the male lung cancer patients had a much higher rate of disagreement with Item 5 compared with prostate cancer patients (37% vs. 18%). Conclusions: Results of this study may afford greater insight and foster better understanding of what patients want from their radiation oncologist. For breast, lung, and prostate cancer patients, initial preferences for their radiation oncologist are generally similar, according to this tool. However, there are important difference among cancer sites (and gender) regarding physical contact at the end of treatment

  19. Parenting practices, parents' underestimation of daughters' risks, and alcohol and sexual behaviors of urban girls.

    Science.gov (United States)

    O'Donnell, Lydia; Stueve, Ann; Duran, Richard; Myint-U, Athi; Agronick, Gail; San Doval, Alexi; Wilson-Simmons, Renée

    2008-05-01

    In urban economically distressed communities, high rates of early sexual initiation combined with alcohol use place adolescent girls at risk for myriad negative health consequences. This article reports on the extent to which parents of young teens underestimate both the risks their daughters are exposed to and the considerable influence that they have over their children's decisions and behaviors. Surveys were conducted with more than 700 sixth-grade girls and their parents, recruited from seven New York City schools serving low-income families. Bivariate and multivariate analyses examined relationships among parents' practices and perceptions of daughters' risks, girls' reports of parenting, and outcomes of girls' alcohol use, media and peer conduct, and heterosexual romantic and social behaviors that typically precede sexual intercourse. Although only four parents thought that their daughters had used alcohol, 22% of the daughters reported drinking in the past year. Approximately 5% of parents thought that daughters had hugged and kissed a boy for a long time or had "hung out" with older boys, whereas 38% of girls reported these behaviors. Parents' underestimation of risk was correlated with lower reports of positive parenting practices by daughters. In multivariate analyses, girls' reports of parental oversight, rules, and disapproval of risk are associated with all three behavioral outcomes. Adult reports of parenting practices are associated with girls' conduct and heterosexual behaviors, but not with their alcohol use. Creating greater awareness of the early onset of risk behaviors among urban adolescent girls is important for fostering positive parenting practices, which in turn may help parents to support their daughters' healthier choices.

  20. Characteristics of lithology and tectonic setting in the Korean peninsula

    International Nuclear Information System (INIS)

    Lee, Byungjoo; Chae, Byunggon; Choi, Junghae

    2011-01-01

    The west coast of the Korean Peninsula is bounded by the Korean Bay to the north and the Yellow Sea to the south; the east coast is bounded by the East Sea. Two hundred kilometers separate the peninsula from eastern China. The Japanese islands of Honshu and Kyushu are located 206 kilometers to the southeast, just across the Korea Strait. Because of its unique geographical location, Chinese culture filtered into Japan through Korea; a common cultural sphere of Buddhism and Confucianism was thus established between the three countries. The total area of the peninsula, including the islands, is 222,154 square kilometers of which about 45 percent, excluding the area in the Demilitarized Zone, constitutes the territory of South Korea. There are about 3,000 islands belonging to Korea. The islands are located mostly around the Yellow Sea; Ulleungdo, the largest island in the East Sea, serves as a major fishery base as does Dokdo island. Important islands within South Korea territory include Jejudo, the largest island, which lies off the southwest corner of the peninsula, Geojedo, Ganghwado, and Namhaedo. Nearly 70 percent of the Korean Peninsula is covered by mountains and hills. Located mostly in the southern and the western regions, these hills give way gradually to increasingly higher mountains toward the eastern and the northern end. On the whole, the western and southern slopes of the peninsula are wide with some plains and basins along rivers, while the eastern slope is very narrow because the high mountains hug the East Sea coastline

  1. Characteristics of lithology and tectonic setting in the Korean peninsula

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Byungjoo; Chae, Byunggon; Choi, Junghae [KIGAM, Daejeon (Korea, Republic of)

    2011-07-01

    The west coast of the Korean Peninsula is bounded by the Korean Bay to the north and the Yellow Sea to the south; the east coast is bounded by the East Sea. Two hundred kilometers separate the peninsula from eastern China. The Japanese islands of Honshu and Kyushu are located 206 kilometers to the southeast, just across the Korea Strait. Because of its unique geographical location, Chinese culture filtered into Japan through Korea; a common cultural sphere of Buddhism and Confucianism was thus established between the three countries. The total area of the peninsula, including the islands, is 222,154 square kilometers of which about 45 percent, excluding the area in the Demilitarized Zone, constitutes the territory of South Korea. There are about 3,000 islands belonging to Korea. The islands are located mostly around the Yellow Sea; Ulleungdo, the largest island in the East Sea, serves as a major fishery base as does Dokdo island. Important islands within South Korea territory include Jejudo, the largest island, which lies off the southwest corner of the peninsula, Geojedo, Ganghwado, and Namhaedo. Nearly 70 percent of the Korean Peninsula is covered by mountains and hills. Located mostly in the southern and the western regions, these hills give way gradually to increasingly higher mountains toward the eastern and the northern end. On the whole, the western and southern slopes of the peninsula are wide with some plains and basins along rivers, while the eastern slope is very narrow because the high mountains hug the East Sea coastline.

  2. THE SPITZER LOCAL VOLUME LEGACY: SURVEY DESCRIPTION AND INFRARED PHOTOMETRY

    International Nuclear Information System (INIS)

    Dale, D. A.; Cohen, S. A.; Johnson, L. C.; Schuster, M. D.; Calzetti, D.; Engelbracht, C. W.; Kennicutt, R. C.; Block, M.; Marble, A. R.; Gil de Paz, A.; Lee, J. C.; Begum, A.; Dalcanton, J. J.; Funes, J. G.; Gordon, K. D.; Johnson, B. D.; Sakai, S.; Skillman, E. D.; Van Zee, L.; Walter, F.

    2009-01-01

    The survey description and the near-, mid-, and far-infrared flux properties are presented for the 258 galaxies in the Local Volume Legacy (LVL). LVL is a Spitzer Space Telescope legacy program that surveys the local universe out to 11 Mpc, built upon a foundation of ultraviolet, Hα, and Hubble Space Telescope imaging from 11HUGS (11 Mpc Hα and Ultraviolet Galaxy Survey) and ANGST (ACS Nearby Galaxy Survey Treasury). LVL covers an unbiased, representative, and statistically robust sample of nearby star-forming galaxies, exploiting the highest extragalactic spatial resolution achievable with Spitzer. As a result of its approximately volume-limited nature, LVL augments previous Spitzer observations of present-day galaxies with improved sampling of the low-luminosity galaxy population. The collection of LVL galaxies shows a large spread in mid-infrared colors, likely due to the conspicuous deficiency of 8 μm polycyclic aromatic hydrocarbon emission from low-metallicity, low-luminosity galaxies. Conversely, the far-infrared emission tightly tracks the total infrared emission, with a dispersion in their flux ratio of only 0.1 dex. In terms of the relation between the infrared-to-ultraviolet ratio and the ultraviolet spectral slope, the LVL sample shows redder colors and/or lower infrared-to-ultraviolet ratios than starburst galaxies, suggesting that reprocessing by dust is less important in the lower mass systems that dominate the LVL sample. Comparisons with theoretical models suggest that the amplitude of deviations from the relation found for starburst galaxies correlates with the age of the stellar populations that dominate the ultraviolet/optical luminosities.

  3. Responsiveness to HIV education and VCT services among Kenyan rural women: a community-based survey.

    Science.gov (United States)

    Karau, Paul Bundi; Winnie, Mueni Saumu; Geoffrey, Muriira; Mwenda, Mukuthuria

    2010-09-01

    Uptake of VCT and other HIV prevention strategies among rural African women is affected by various socio-cultural and economic factors which need elucidation. Our aim was to establish the responsiveness to HIV education among rural women attending three dispensaries in Kenya. This study was designed to assess gender and psycho-social factors that influence HIV dynamics in rural Kenya. This was a cross-sectional questionnaire based study of 1347 women, conducted in October 2009. Socio-economic status as well as knowledge on methods of HIV transmission was assessed. Testing status, knowledge on existing VCT services and willingness to share HIV information with their children was assessed. Majority of the women have heard about VCT services, but significantly few of them have been tested. Those with secondary school education and above are more knowledgeable on methods of HIV transmission, while those with inadequate education are more likely to cite shaking hands, sharing utensils, mosquito bites and hugging as means of transmission (p = 0.001). 90% of educated women are willing to share HIV information with their children, compared to 40% of uneducated women. Marital status is seen to positively influence testing status, but has no significant effect on dissemination of information to children. We conclude that despite the aggressive HIV education and proliferation of VCT services in Kenya, women are not heeding the call to get tested. Education has a positive impact on dissemination of HIV information. Focus needs to shift into increasing acceptability of testing by women in rural Kenya.

  4. Framatome, from the nuclear engineering office to the international group; Framatome, du bureau d'ingenierie nucleaire au groupe international

    Energy Technology Data Exchange (ETDEWEB)

    Lorin, Philippe [Direction de la Communication, FRAMATOME, Tour Framatome, 92084 Paris La Defense Cedex (France)

    1995-07-01

    A simple office of studies by its inceptions, Framatome became during 30 years an international and diversified group, a world nuclear leader, as designer-manufacturer, fuel supplier and servicing provider. It asserts itself also as a foreground actor in the industrial equipment and connections. This book not only presents an exciting and capital episode of the history of nuclear energy in France but it demonstrate also how an company with a little bit of chance, a lot of endeavour, a plenty of talent and a huge firmness succeeded in becoming an incontestable reference authority in its sector. Staking on technological choices, although different from the creeds inspiring the French decision makers, Framatome has obtained its first orders ahead other French companies, much more powerful and prestigious at the time. The impressive Framatome evolution is presented along six chapters entitled as follows: 1. Beginning of nuclear power; 2. Technological challenge; 3. Industrial challenge; 4. Sectorial challenge; 5. Management challenge; 6. Future. The following four witness' papers are inserted with in the main text: 1. Beginning of Framatome (by P. Boulin); 2. The difficult choice for the PWR system (by M. Boiteux); 3. Impossibly is not French (by A. Giraud); 4. A fabulous common effort (by M. Hug). The book is addressed to the public at large but aims also at the Company's personnel, both the people witnessing the Company's beginning and the newcomers who should know the social body they have chosen to join and to the effort of which they have to contribute with their inventiveness and dynamism.

  5. Renegotiating sexuality and intimacy in the context of cancer: the experiences of carers.

    Science.gov (United States)

    Gilbert, Emilee; Ussher, Jane M; Perz, Janette

    2010-08-01

    There is a growing body of evidence to show that cancer can result in dramatic changes in sexuality, sexual functioning, and intimate couple relationships, with significant implications for both quality of life and psychological well-being. However, the experiences of intimate partners are often neglected in research on sexuality and intimacy in the context of cancer. This study used a material-discursive framework and a qualitative methodology to investigate the ways in which intimacy and sexuality are renegotiated in the context of cancer, and what factors are associated with successful or unsuccessful renegotiation, from the perspective of partners caring for a person with cancer. Twenty participants were interviewed, across a range of cancer types, stages, and age groups. Eleven participants reported that they were unable to negotiate other ways of being sexually intimate when penetrative sexual intercourse was no longer physiologically possible or desirable. Nine were able to renegotiate sexual intimacy in the context of cancer to include practices previously positioned as secondary to "real sex," such as mutual masturbation, self masturbation, manual stimulation, oral sex, massage, the use of vibrators, kissing, and hugging. Grounded theory analysis identified two themes associated with renegotiation: "Alternative" sexual practices-redefining sexual intimacy, and couple communication and relationship context. Difficulties in renegotiation were associated with adherence to the coital imperative, sexual relationship or communication problems which existed prior to cancer, and the positioning of the person with cancer as a child or an asexual sick patient rather than a sexual partner. The implications for health professional intervention to ameliorate changes to sexuality in the context of cancer are discussed.

  6. Asymptotics of bivariate generating functions with algebraic singularities

    Science.gov (United States)

    Greenwood, Torin

    Flajolet and Odlyzko (1990) derived asymptotic formulae the coefficients of a class of uni- variate generating functions with algebraic singularities. Gao and Richmond (1992) and Hwang (1996, 1998) extended these results to classes of multivariate generating functions, in both cases by reducing to the univariate case. Pemantle and Wilson (2013) outlined new multivariate ana- lytic techniques and used them to analyze the coefficients of rational generating functions. After overviewing these methods, we use them to find asymptotic formulae for the coefficients of a broad class of bivariate generating functions with algebraic singularities. Beginning with the Cauchy integral formula, we explicity deform the contour of integration so that it hugs a set of critical points. The asymptotic contribution to the integral comes from analyzing the integrand near these points, leading to explicit asymptotic formulae. Next, we use this formula to analyze an example from current research. In the following chapter, we apply multivariate analytic techniques to quan- tum walks. Bressler and Pemantle (2007) found a (d + 1)-dimensional rational generating function whose coefficients described the amplitude of a particle at a position in the integer lattice after n steps. Here, the minimal critical points form a curve on the (d + 1)-dimensional unit torus. We find asymptotic formulae for the amplitude of a particle in a given position, normalized by the number of steps n, as n approaches infinity. Each critical point contributes to the asymptotics for a specific normalized position. Using Groebner bases in Maple again, we compute the explicit locations of peak amplitudes. In a scaling window of size the square root of n near the peaks, each amplitude is asymptotic to an Airy function.

  7. Situational Variability of Means of Expression of Positive Emotions in Modern English

    Directory of Open Access Journals (Sweden)

    Alina K. Kisil

    2017-06-01

    Full Text Available The article investigates situational variability of means of expression of positive emotions in Modern English. This problem is topical for linguistics of emotions, pragma- and sociolinguistics. The author analyzes verbal, paraverbal and nonverbal means of expressing positive emotions of joy and surprise in three communicative registers: official, neutral and unofficial. These registers are singled out on the basis of situational context and participants of the situation. The investigation gave the author the opportunity to come to the conclusion that in the official register emotions are controlled and very often are subject to strategic purposes. They implement the upgrading strategy the aim of which is to give a high evaluation of the addressee and of everything what is happening. It stipulates the use of corresponding expressive words and word combinations, exclamatory sentences, repetitions and rhetorical questions. Paraverbal means include only light laughter and nonverbal – a smile, the expression of the eyes, nods and tangled breath. The range of the means in question is wider in the neutral register where the speaker can use such verbal means as interjections with long sounds, expletives, pauses, descriptions of own emotions. Such paraverbal means as the emotional color of the voice and its volume, intonation, different kinds of laughter and such nonverbal means as different kinds of smile, the expression of the face, gestures and movements are also used. Unofficial register is especially rich in means of expressing positive emotions. Besides means typical of other registers such verbal means as obscene lexicon, phrasal words and graphical means are used here. Paraverbal means include numerous verbs reflecting the volume of voice and nonverbal – rich mimic, friendly hugs and kisses.

  8. Surfaceome and Proteosurfaceome in Parietal Monoderm Bacteria: Focus on Protein Cell-Surface Display

    Directory of Open Access Journals (Sweden)

    Mickaël Desvaux

    2018-02-01

    Full Text Available The cell envelope of parietal monoderm bacteria (archetypal Gram-positive bacteria is formed of a cytoplasmic membrane (CM and a cell wall (CW. While the CM is composed of phospholipids, the CW is composed at least of peptidoglycan (PG covalently linked to other biopolymers, such as teichoic acids, polysaccharides, and/or polyglutamate. Considering the CW is a porous structure with low selective permeability contrary to the CM, the bacterial cell surface hugs the molecular figure of the CW components as a well of the external side of the CM. While the surfaceome corresponds to the totality of the molecules found at the bacterial cell surface, the proteinaceous complement of the surfaceome is the proteosurfaceome. Once translocated across the CM, secreted proteins can either be released in the extracellular milieu or exposed at the cell surface by associating to the CM or the CW. Following the gene ontology (GO for cellular components, cell-surface proteins at the CM can either be integral (GO: 0031226, i.e., the integral membrane proteins, or anchored to the membrane (GO: 0046658, i.e., the lipoproteins. At the CW (GO: 0009275, cell-surface proteins can be covalently bound, i.e., the LPXTG-proteins, or bound through weak interactions to the PG or wall polysaccharides, i.e., the cell wall binding proteins. Besides monopolypeptides, some proteins can associate to each other to form supramolecular protein structures of high molecular weight, namely the S-layer, pili, flagella, and cellulosomes. After reviewing the cell envelope components and the different molecular mechanisms involved in protein attachment to the cell envelope, perspectives in investigating the proteosurfaceome in parietal monoderm bacteria are further discussed.

  9. Alterações renais nas doenças falciformes Renal abnormalities in sickle cell disease

    Directory of Open Access Journals (Sweden)

    Isis Q. Magalhães

    2007-09-01

    Full Text Available A doença falciforme associa-se a anormalidades renais estruturais glomerulares e tubulares, alterações hemodinâmicas e da síntese dos hormônios renais (eritropoetina, renina e prostaglandinas. Estas se iniciam na infância, em conseqüência da anemia crônica, fluxo sangüíneo aumentado, e eventos de veno-oclusão intraparenquimatosos, principalmente na medular renal. Na doença SS, a taxa de filtração glomerular encontra-se elevada desde os primeiros anos de vida e decresce com a idade. Decorrente de anormalidade tubular distal está a hipostenúria com as manifestações clínicas de poliúria, noctúria, enurese e susceptibilidade a desidratação, diminuição da capacidade de acidificar urina e excretar potássio. As anormalidades de túbulo proximal se traduzem por secreção aumentada de creatinina e ácido úrico, reabsorção aumentada de fosfatos e b2-microglobulina. A hipersecreção de creatinina superestima a taxa de filtração glomerular (FG, tornando o clearance de creatinina impróprio como detector precoce da deterioração da função renal. A proteinúria ocorre em 29%-50% dos pacientes acima de 10 anos de idade; 2/3 destes evoluem para insuficiência renal crônica de evolução ruim. A literatura apresenta benefícios consistentes com o uso de inibidores de enzimas conversoras de angiotensina (IECA na redução da proteinúria, que talvez tenha impacto na progressão da insuficiência renal. Microalbuminúria (MA é um marcador sensível da glomerulopatia falcêmica que precede a proteinúria. Na população pediátrica documenta-se prevalência de 19%, estando associado com idade, síndrome torácica aguda, níveis de Hb baixos e altas de leucometrias. Recomenda-se screening para MA a partir de 10 anos de idade. Em andamento estudo multicêntrico com uso precoce de hidroxiuréia na prevenção das lesões orgânicas crônicas (Baby HUG.Sickle cell disease is associated with glomerular and tabular structural

  10. Liftoff of the 18 May 1980 surge of Mount St. Helens (USA) and the deposits left behind

    Science.gov (United States)

    Gardner, James E.; Andrews, Benjamin J.; Dennen, Robert

    2017-01-01

    The distance that ground-hugging pyroclastic density currents travel is limited partly by when they reverse buoyancy and liftoff into the atmosphere. It is not clear, however, what deposits are left behind by lofting flows. One current that was seen to liftoff was the surge erupted from Mount St. Helens on the morning of 18 May 1980. Before lofting, it had leveled a large area of thick forest (the blowdown zone). The outer edge of the devastated area—where trees were scorched but left standing (the scorched zone)—is where the surge is thought to have lifted off. Deposits in the outer parts of the blowdown and in the scorched zone were examined at 32 sites. The important finding is that the laterally moving surge traveled through the scorched zone, and hence, the change in tree damage does not mark the runout distance of the surge. Buoyancy reversal and liftoff are thus not preserved in the deposits where the surge lofted upwards. We propose, based on interpretation of eyewitness accounts and the impacts of the surge on trees and vehicles, that the surge consisted of a faster, dilute "overcurrent" and a slower "undercurrent," where most of the mass (and heat) was retained. Reasonable estimates for flow density and velocity show that dynamic pressure of the surge (i.e., its ability to topple trees) peaked near the base of the overcurrent. We propose that where the overcurrent began to liftoff, the height of peak dynamic pressure rose above the trees and stopped toppling them. The slower undercurrent continued forward, however, scorching trees, but lacked the dynamic pressure needed to topple them. Grain-size variations argue that it slowed from ˜30 m s-1 when it entered the scorched zone to ˜3 m s-1 at the far end.

  11. A track-event theory of cell survival

    Energy Technology Data Exchange (ETDEWEB)

    Besserer, Juergen; Schneider, Uwe [Zuerich Univ. (Switzerland). Inst. of Physics; Radiotherapy Hirslanden, Zuerich (Switzerland)

    2015-09-01

    When fractionation schemes for hypofractionation and stereotactic body radiotherapy are considered, a reliable cell survival model at high dose is needed for calculating doses of similar biological effectiveness. In this work a simple model for cell survival which is valid also at high dose is developed from Poisson statistics. An event is defined by two double strand breaks (DSB) on the same or different chromosomes. An event is always lethal due to direct lethal damage or lethal binary misrepair by the formation of chromosome aberrations. Two different mechanisms can produce events: one-track events (OTE) or two-track-events (TTE). The target for an OTE is always a lethal event, the target for an TTE is one DSB. At least two TTEs on the same or different chromosomes are necessary to produce an event. Both, the OTE and the TTE are statistically independent. From the stochastic nature of cell kill which is described by the Poisson distribution the cell survival probability was derived. It was shown that a solution based on Poisson statistics exists for cell survival. It exhibits exponential cell survival at high dose and a finite gradient of cell survival at vanishing dose, which is in agreement with experimental cell studies. The model fits the experimental data nearly as well as the three-parameter formula of Hug-Kellerer and is only based on two free parameters. It is shown that the LQ formalism is an approximation of the model derived in this work. It could be also shown that the derived model predicts a fractionated cell survival experiment better than the LQ-model. It was shown that cell survival can be described with a simple analytical formula on the basis of Poisson statistics. This solution represents in the limit of large dose the typical exponential behavior and predicts cell survival after fractionated dose application better than the LQ-model.

  12. A track-event theory of cell survival

    International Nuclear Information System (INIS)

    Besserer, Juergen; Schneider, Uwe

    2015-01-01

    When fractionation schemes for hypofractionation and stereotactic body radiotherapy are considered, a reliable cell survival model at high dose is needed for calculating doses of similar biological effectiveness. In this work a simple model for cell survival which is valid also at high dose is developed from Poisson statistics. An event is defined by two double strand breaks (DSB) on the same or different chromosomes. An event is always lethal due to direct lethal damage or lethal binary misrepair by the formation of chromosome aberrations. Two different mechanisms can produce events: one-track events (OTE) or two-track-events (TTE). The target for an OTE is always a lethal event, the target for an TTE is one DSB. At least two TTEs on the same or different chromosomes are necessary to produce an event. Both, the OTE and the TTE are statistically independent. From the stochastic nature of cell kill which is described by the Poisson distribution the cell survival probability was derived. It was shown that a solution based on Poisson statistics exists for cell survival. It exhibits exponential cell survival at high dose and a finite gradient of cell survival at vanishing dose, which is in agreement with experimental cell studies. The model fits the experimental data nearly as well as the three-parameter formula of Hug-Kellerer and is only based on two free parameters. It is shown that the LQ formalism is an approximation of the model derived in this work. It could be also shown that the derived model predicts a fractionated cell survival experiment better than the LQ-model. It was shown that cell survival can be described with a simple analytical formula on the basis of Poisson statistics. This solution represents in the limit of large dose the typical exponential behavior and predicts cell survival after fractionated dose application better than the LQ-model.

  13. Biogeochemistry of mercury and methylmercury in sediment cores from Sundarban mangrove wetland, India--a UNESCO World Heritage Site.

    Science.gov (United States)

    Chatterjee, Mousumi; Canário, João; Sarkar, Santosh Kumar; Branco, Vasco; Godhantaraman, Nallamuthu; Bhattacharya, Bhaskar Deb; Bhattacharya, Asokkumar

    2012-09-01

    This study was performed to elucidate the distribution, concentration trend and possible sources of total mercury (Hg(T)) and methylmercury (MeHg) in sediment cores (<63 μm particle size; n = 75) of Sundarban mangrove wetland, northeastern part of the Bay of Bengal, India. Total mercury was determined by atomic absorption spectrometry (AAS) in a Leco AMA 254 instrument and MeHg by gas chromatography-atomic fluorescence spectrometry (GC-AFS). A wide range of variation in Hg(T) (0.032-0.196 μg g(-1) dry wt.) as well as MeHg (0.04-0.13 ng g(-1) dry wt.) concentrations revealed a slight local contamination. The prevalent low Hg(T) levels in sediments could be explained by sediment transport by the tidal Hugli (Ganges) River that would dilute the Hg(T) values via sediment mixing processes. A broader variation of MeHg proportions (%) were also observed in samples suggesting that other environmental variables such as organic carbon and microbial activity may play a major role in the methylation process. An overall elevated concentration of Hg(T) in surface layers (0-4 cm) of the core is due to remobilization of mercury from deeper sediments. Based on the index of geoaccumulation (I (geo)) and low effects-range (ER-L) values, it is considered that the sediment is less polluted by Hg(T) and there is less ecotoxicological risk. The paper provides the first information of MeHg in sediments from this wetland environment and the authors strongly recommend further examination of Hg(T) fluxes for the development of a detailed coastal MeHg model. This could provide more refine estimates of a total flux into the water column.

  14. Using a social story intervention to decrease inappropriate behavior of preschool children with autism

    Directory of Open Access Journals (Sweden)

    Angkhana Khantreejitranon

    2018-01-01

    Full Text Available This research investigated the inappropriate behavior of preschool children with autism in a classroom and examined the effectiveness of the use of social stories to decrease inappropriate autistic behavior. An A-B-A-B single subject design was used across the five participants selected for the study. Investigating the problematic social skills and developing a social story intervention for the preschool autistic children was completed, followed by an examination of the effectiveness of the social story intervention. Ten common problematic social skills among the autistic children in preschool were identified—walking around, making loud noises, not sharing their toys with others, showing frustration when feeling unsatisfied, having no patience, not putting toys away when finished, taking other people's belongings without permission, not knowing how to greet others, destroying things when feeling frustrated, and giving a hug to other people at inappropriate times. It was found that the social story intervention helped to decrease inappropriate behavior in children with autism. The social story intervention consisted of five social story books and five e-books (one story per child using a single subject design with an A-B-A-B pattern. The autistic children preferred social stories from the hardcopy books compared with stories from the e-books. A fourth stage time trial was used over 6 weeks, five times per week, for a total of 30 times. The findings suggested that the use of properly constructed social stories can be effective in decreasing the inappropriate behavior of children with autism. However, each story intervention should be applied with caution because of individual differences between children. The social story intervention should be designed only for autistic children who exhibit specific inappropriate social behavior. Keywords: autistic child, inappropriate behavior, social skills, social story

  15. Analyzing the dose-dependence of the Saccharomyces cerevisiae global transcriptional response to methyl methanesulfonate and ionizing radiation.

    Science.gov (United States)

    Benton, Michael G; Somasundaram, Swetha; Glasner, Jeremy D; Palecek, Sean P

    2006-12-01

    One of the most crucial tasks for a cell to ensure its long term survival is preserving the integrity of its genetic heritage via maintenance of DNA structure and sequence. While the DNA damage response in the yeast Saccharomyces cerevisiae, a model eukaryotic organism, has been extensively studied, much remains to be elucidated about how the organism senses and responds to different types and doses of DNA damage. We have measured the global transcriptional response of S. cerevisiae to multiple doses of two representative DNA damaging agents, methyl methanesulfonate (MMS) and gamma radiation. Hierarchical clustering of genes with a statistically significant change in transcription illustrated the differences in the cellular responses to MMS and gamma radiation. Overall, MMS produced a larger transcriptional response than gamma radiation, and many of the genes modulated in response to MMS are involved in protein and translational regulation. Several clusters of coregulated genes whose responses varied with DNA damaging agent dose were identified. Perhaps the most interesting cluster contained four genes exhibiting biphasic induction in response to MMS dose. All of the genes (DUN1, RNR2, RNR4, and HUG1) are involved in the Mec1p kinase pathway known to respond to MMS, presumably due to stalled DNA replication forks. The biphasic responses of these genes suggest that the pathway is induced at lower levels as MMS dose increases. The genes in this cluster with a threefold or greater transcriptional response to gamma radiation all showed an increased induction with increasing gamma radiation dosage. Analyzing genome-wide transcriptional changes to multiple doses of external stresses enabled the identification of cellular responses that are modulated by magnitude of the stress, providing insights into how a cell deals with genotoxicity.

  16. Differences between Internet samples and conventional samples of men who have sex with men: implications for research and HIV interventions.

    Science.gov (United States)

    Ross, M W; Tikkanen, R; Månsson, S A

    2000-09-01

    The Internet is becoming a new erotic oasis for obtaining sex online or in person. We reviewed the literature on cybersex and compared differences in data from samples of homosexually active men obtained on identical questionnaires from a conventional written questionnaire, distributed through the mailing and contact lists of a large national gay organization in Sweden, and through the same organization's website and chat room. A total of 716 written questionnaires and 678 Internet questionnaires were obtained. The Internet sample was younger, more likely to live in small towns or cities, live with parents or a girlfriend, and have lower formal education. They are less likely to have previous sexual experience solely with other men (one in three of the Internet sample vs. 1 in 14 of the written sample defined themselves as bisexual) and more likely to visit erotic oases such as bathhouses, video clubs and erotic movie houses. They also visited Internet chat rooms more frequently (86% of the Internet sample vs. 50% of the written sample). One third of the Internet sample wanted the opportunity to talk with an expert about HIV compared with a quarter of the written sample. Sexual practices between the two samples were generally similar, although the Internet sample reported significantly less body contact, kissing, hugging, mutual masturbation, and more condom use for anal intercourse with steady partners. Over four times as many of the Internet samples reported sex with women in the past year as the written sample. These data indicate that Internet data collection is feasible and that this mode of data collection, despite the nonrandom and self-selected nature of both types of samples, is likely to be more significantly oriented toward the young, geographically more isolated, and more behaviorally and self-identified bisexual respondent than conventionally distributed written questionnaires.

  17. Co-expression modules construction by WGCNA and identify potential prognostic markers of uveal melanoma.

    Science.gov (United States)

    Wan, Qi; Tang, Jing; Han, Yu; Wang, Dan

    2018-01-01

    Uveal melanoma is an aggressive cancer which has a high percentage recurrence and with a worse prognosis. Identify the potential prognostic markers of uveal melanoma may provide information for early detection of recurrence and treatment. RNA sequence data of uveal melanoma and patient clinic traits were obtained from The Cancer Genome Atlas (TCGA) database. Co-expression modules were built by weighted gene co -expression network analysis (WGCNA) and applied to investigate the relationship underlying modules and clinic traits. Besides, functional enrichment analysis was performed on these co-expression genes from interested modules. First, using WGCNA, identified 21 co-expression modules were constructed by the 10975 genes from the 80 human uveal melanoma samples. The number of genes in these modules ranged from 42 to 5091. Found four co -expression modules significantly correlated with three clinic traits (status, recurrence and recurrence Time). Module red, and purple positively correlated with patient's life status and recurrence Time. Module green positively correlates with recurrence. The result of functional enrichment analysis showed that the module magenta was mainly enriched genetic material assemble processes, the purple module was mainly enriched in tissue homeostasis and melanosome membrane and the module red was mainly enriched metastasis of cell, suggesting its critical role in the recurrence and development of the disease. Additionally, identified the hug gene (top connectivity with other genes) in each module. The hub gene SLC17A7, NTRK2, ABTB1 and ADPRHL1 might play a vital role in recurrence of uveal melanoma. Our findings provided the framework of co-expression gene modules of uveal melanoma and identified some prognostic markers might be detection of recurrence and treatment for uveal melanoma. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. The Sexual Behaviour of Secondary School Adolescent Students in Tanzania: Patterns and Trends

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    Madan Mohan Laddunuri

    2013-01-01

    Full Text Available Introduction: A surge of sexual interest occurs around puberty and continues through adolescence. Heightened adolescent sexuality may be caused by a number of factors, including bodily changes, sexual hormones, social forces, and rehearsal for adult gender roles. The main objective of the present study is to understand the patterns and trends of adolescent students’ sexual behaviour in Tanzania.Methodology: A descriptive cross sectional study was conducted and 550 secondary school students (13 to 19 years old were recruited by using a multistage random sampling technique from Tanzania’s secondary schools. The data collection tool was a structured questionnaire. Data were analysed by using SPSS software package version 16.Results: More than one third (40.2% of the participant students had experienced intercourse with mean age 17.2±1.8 years and one sixth (17.6% of the participants had multiple sexual partners. The mean age for hugging, kissing and breast fondling was significantly younger when compared to the sexual intercourse. Most (78.5% of the students had used contraceptives but the frequency of contraception was less than half (48.6% “always”. The main reasons beyond sexual debut were “just for fun” (37% and “peer pressure” (27.6%. A male student was 1.46 times more likely to have had intercourse than a female. Parental education was the most significant association with sexual debut of adolescents and the odds ratio indicates that sexual intercourse among students is decreasing with the increasing of parental education.Conclusion: A relatively high sexual intercourse has been recorded and risky sexual behaviour also existed among the respondents. Hence, there is a need to promote specific intervention programmes built upon those factors which are associated with an increased likelihood for early sexual debut and risky sexual behaviour.

  19. Nutrient Removal Vis-à-Vis Change in Partial Pressure of CO2 During Post-Monsoon Season in a Tropical Lentic and Lotic Aquatic Body: A Comparative Study

    Science.gov (United States)

    Bhattacharyya, Sourav; Chanda, Abhra; Das, Sourav; Akhand, Anirban; Pattanaik, Suchismita; Choudhury, S. B.; Dutta, Dibyendu; Hazra, Sugata

    2018-04-01

    The rate of nutrient removal and changes in pCO2 (water) were compared between a lentic aquaculture pond [East Kolkata Wetlands (EKW), India] and a lotic estuarine system [Diamond Harbor (DH) in Hugli Estuary, India] during the post-monsoon season (experiencing a similar tropical climate) by means of ex situ microcosm experiment. Though the DH waters were found to be substantial source of CO2 towards atmosphere and EKW waters to be sink for CO2 (according to the initial concentration of CO2), the eight consecutive days microcosm experiment revealed that the nutrient removal and pCO2 reduction efficiency were significantly higher in DH (ΔpCO2—90%) compared to EKW (ΔpCO2—78%). Among the five nutrients studied [dissolved nitrate-nitrogen (NO3-N), dissolved ammonium nitrogen (NH4-N), silicate, phosphate and iron], dissolved NO3-N followed by NH4-N was the most utilized in both EKW and DH. Except silicate, the other nutrients reduced to 78-91% in EKW and 84-99% in DH samples of their initial concentrations. Chlorophyll-a concentration steadily depleted in EKW ( 68-26 mg m-3) during the experiment indicating intense zooplankton grazing, whereas in DH it increased rapidly ( 3.4-23 mg m-3) with decreasing pCO2 (water). The present observations further indicated that regular flushing of EKW aquaculture ponds is required to avoid stagnation of water column which would enhance the zooplankton grazing and hamper the primary production of an otherwise sink of CO2. In DH, controlled freshwater discharge from Farakka and reduction of untreated organic waste might allow the existing phytoplankton community to enhance their photosynthetic activity.

  20. A buoyant plume adjacent to a headland-Observations of the Elwha River plume

    Science.gov (United States)

    Warrick, J.A.; Stevens, A.W.

    2011-01-01

    Small rivers commonly discharge into coastal settings with topographic complexities - such as headlands and islands - but these settings are underrepresented in river plume studies compared to more simplified, straight coasts. The Elwha River provides a unique opportunity to study the effects of coastal topography on a buoyant plume, because it discharges into the Strait of Juan de Fuca on the western side of its deltaic headland. Here we show that this headland induces flow separation and transient eddies in the tidally dominated currents (O(100. cm/s)), consistent with other headlands in oscillatory flow. These flow conditions are observed to strongly influence the buoyant river plume, as predicted by the "small-scale" or "narrow" dynamical classification using Garvine's (1995) system. Because of the transient eddies and the location of the river mouth on the headland, flow immediately offshore of the river mouth is directed eastward twice as frequently as it is westward. This results in a buoyant plume that is much more frequently "bent over" toward the east than the west. During bent over plume conditions, the plume was attached to the eastern shoreline while having a distinct, cuspate front along its westernmost boundary. The location of the front was found to be related to the magnitude and direction of local flow during the preceding O(1. h), and increases in alongshore flow resulted in deeper freshwater mixing, stronger baroclinic anomalies, and stronger hugging of the coast. During bent over plume conditions, we observed significant convergence of river plume water toward the frontal boundary within 1. km of the river mouth. These results show how coastal topography can strongly influence buoyant plume behavior, and they should assist with understanding of initial coastal sediment dispersal pathways from the Elwha River during a pending dam removal project. ?? 2010.

  1. Analyzing the dose-dependence of the Saccharomyces cerevisiae global transcriptional response to methyl methanesulfonate and ionizing radiation

    Directory of Open Access Journals (Sweden)

    Glasner Jeremy D

    2006-12-01

    Full Text Available Abstract Background One of the most crucial tasks for a cell to ensure its long term survival is preserving the integrity of its genetic heritage via maintenance of DNA structure and sequence. While the DNA damage response in the yeast Saccharomyces cerevisiae, a model eukaryotic organism, has been extensively studied, much remains to be elucidated about how the organism senses and responds to different types and doses of DNA damage. We have measured the global transcriptional response of S. cerevisiae to multiple doses of two representative DNA damaging agents, methyl methanesulfonate (MMS and gamma radiation. Results Hierarchical clustering of genes with a statistically significant change in transcription illustrated the differences in the cellular responses to MMS and gamma radiation. Overall, MMS produced a larger transcriptional response than gamma radiation, and many of the genes modulated in response to MMS are involved in protein and translational regulation. Several clusters of coregulated genes whose responses varied with DNA damaging agent dose were identified. Perhaps the most interesting cluster contained four genes exhibiting biphasic induction in response to MMS dose. All of the genes (DUN1, RNR2, RNR4, and HUG1 are involved in the Mec1p kinase pathway known to respond to MMS, presumably due to stalled DNA replication forks. The biphasic responses of these genes suggest that the pathway is induced at lower levels as MMS dose increases. The genes in this cluster with a threefold or greater transcriptional response to gamma radiation all showed an increased induction with increasing gamma radiation dosage. Conclusion Analyzing genome-wide transcriptional changes to multiple doses of external stresses enabled the identification of cellular responses that are modulated by magnitude of the stress, providing insights into how a cell deals with genotoxicity.

  2. Migrating Seals on Shifting Sands: Testing Alternate Hypotheses for Holocene Ecological and Cultural Change on the California Coast

    Science.gov (United States)

    Koch, P. L.; Newsome, S. D.; Gifford-Gonzalez, D.

    2001-12-01

    The coast of California presented Holocene humans with a diverse set of ecosystems and geomorphic features, from large islands off a semi-desert mainland in the south, to a mix of sandy and rocky beaches abutting grassland and oak forest in central California, to a rocky coast hugged by dense coniferous forest in the north. Theories explaining trends in human resource use, settlement patterns, and demography are equally diverse, but can be categorized as 1) driven by diffusion of technological innovations from outside the region, 2) driven by population growth leading to more intensive extraction of resources, or 3) driven by climatic factors that affect the resource base. With respect to climatic shifts, attention has focused on a possible regime shift ca. 5500 BP, following peak Holocene warming, and on evidence for massive droughts and a drop in marine productivity ca. 1000 BP. While evidence for a coincidence between climatic, cultural, and ecological change is present, albeit complex, in southern California, similar data are largely lacking from central and northern California. We are using isotopic and archaeofaunal analysis to test ideas for ecological and cultural change in central California. Three features of the archaeological record are relevant. First, overall use of marine resources by coastal communities declined after 1000 BP. Second, northern fur seals, which are common in earlier sites, drop in abundance relative to remaining marine animals. We have previously established that Holocene humans in central California were hunting gregariously-breeding northern fur seals from mainland rookeries. These seals breed exclusively on offshore islands today, typically at high latitudes. Their restriction to these isolated sites today may be a response to human overexploitation of their mainland rookeries prehistorically. Finally, collection of oxygen and carbon isotope data from mussels at the archaeological sites, while still in a preliminary phase, has

  3. The Place of Complementary Medicine in the Treatment of Autistic Children

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    Özgür Taşkıran Konaç

    2016-03-01

    Full Text Available Objectives: The purpose of this study is to achieve a vision for autistic children and their parents aimed at generating interest in ideas such as “Sanitas Per Aquam” (SPA, massage and music therapy, which has begun to have widespread use and to attract attention. Methods: This cross-sectional, descriptive study was carried out with autistic children and their parents from February to April 2015 in Muğla, Turkey. The study was began by interviewing experts in the field and by developing a suitable assessment questionnaire. In order to direct the flow of conversation between the researchers and the autisitc children and their parents, the researchers conducted semi-structured face to face interviews in a form that had been determined by using reports in the literature and the opinions of experts in the field. Results: Forty two boys (84% and eight girls (16% with autism participated in our study. Children in the 0 ─ 7 age group spent long time in the bathroom (P = 0.001. Boys liked to be hugged more than girls (P = 0.01. Children ages 0 ─ 7 years liked bright lighting while those 15 years of age and older liked gloomy lighting (P = 0.009. Except for these statistically significant sex- and age-related differences, no other statistically significant differences were noted in the parameters of this study. Although the result was not statistically significant, more children with mild autism disorder obeyed commands like inhale or exhale (P = 0.051. Conclusion: Treatment for autism spectrum disorders is not yet fully possible, so many studies are being done to alleviate some symptoms and to improve the quality of life for individuals with autism and their families. As a result of our study, whether touching the areas the children want touched and listening to their favorite music are required to stimulate the brain remain as questions in our minds.

  4. DWARF GALAXY STARBURST STATISTICS IN THE LOCAL VOLUME

    International Nuclear Information System (INIS)

    Lee, Janice C.; Kennicutt, Robert C.; Akiyama, Sanae; Funes, S. J. Jose G.; Sakai, Shoko

    2009-01-01

    An unresolved question in galaxy evolution is whether the star formation histories (SFHs) of low-mass systems are preferentially dominated by starbursts or modes that are more quiescent and continuous. Here, we quantify the prevalence of global starbursts in dwarf galaxies at the present epoch and infer their characteristic durations and amplitudes. The analysis is based on the Hα component of the 11 Mpc Hα UV Galaxy Survey (11HUGS), which provides Hα and Galaxy Evolution Explorer UV imaging for an approximately volume-limited sample of ∼ 300 star-forming galaxies within 11 Mpc. We first examine the completeness properties of the sample, and then directly tally the number of bursting dwarfs and compute the fraction of star formation that is concentrated in such systems. To identify starbursting dwarfs, we use an integrated Hα equivalent width (EW) threshold of 100 A, which corresponds to a stellar birthrate of ∼ 2.5, and also explore the use of empirical starburst definitions based on σ thresholds of the observed logarithmic EW distributions. Our results are robust to the exact choice of the threshold, and are consistent with a picture where dwarfs that are currently experiencing massive global bursts are just the ∼ 6% tip of a low-mass galaxy iceberg. Moreover, bursts are only responsible for about a quarter of the total star formation in the overall dwarf population, so the majority of stars in low-mass systems are not formed in this mode today. Spirals and irregulars devoid of Hα emission are rare, indicating that the complete cessation of star formation generally does not occur in such galaxies and is not characteristic of the interburst state, at least for the more luminous systems with M B < -15. The starburst statistics presented here directly constrain the duty cycle and the average burst amplitude under the simplest assumptions where all dwarf irregulars share a common SFH and undergo similar burst cycles with equal probability. Uncertainties

  5. Observation and modeling of hydrothermal response to the 2015 eruption at Axial Seamount, Northeast Pacific: An OOI Cabled Observatory case study

    Science.gov (United States)

    Xu, G.; Chadwick, W. W., Jr.; Wilcock, W. S. D.; Bemis, K. G.; Nooner, S. L.; Sasagawa, G. S.; Zumberge, M. A.; Delaney, J. R.

    2017-12-01

    The 2015 eruption at Axial Seamount, an active volcano at a depth of 1500 m in the Northeast Pacific, marked the first time a seafloor eruption was detected and monitored by a cabled observatory - the Cabled Array operated by Ocean Observatories Initiative (OOI). Following the eruption, eight cabled and non-cabled instruments recorded a temperature increase across the southern half of the caldera and neighboring areas. These temperature signals were very different from those observed after the 2011 and 1998 Axial eruptions. The 2015 temperature increase occurred later (3.5 days after deflation started versus 6-18 hours) and had a larger amplitude ( 0.7°C versus 0.2-0.5°C), a much slower increase and decay and smaller short-term fluctuations. Most remarkably, the 2015 temperature signals were synchronous and uniform across the 3 x 4.5 km2 area covered by the eight instruments. We hypothesize that the eruption triggered the release of a hydrothermal brine stored in the crust. In this interpretation, the observed temperature increases were due to a dense, bottom-hugging layer of warm salty water that was created when hot brine in the crust was flushed out after the dike intersected the zone where the brine was stored. In the absence of near-bottom salinity observations, we test this hypothesis by using a numerical model of ocean flow and transport to simulate the thermal response within the vicinity of the caldera following a brine injection. We set up the model with realistic background flows, hydrography, and seafloor topography. We simulate brine release as seafloor heat and salt inputs at locations inferred from seismic and geologic observations. Comparison of model bottom temperature with measurements shows a reasonable match. If our interpretation is correct, this is the first time that the release of a hydrothermal brine has been observed due to a submarine eruption. Prior to the next eruption, the Cabled Array observatory should be enhanced to improve the

  6. Pyroclastic Density Current Hazards in the Auckland Volcanic Field, New Zealand

    Science.gov (United States)

    Brand, B. D.; Gravley, D.; Clarke, A. B.; Bloomberg, S. H.

    2012-12-01

    The most dangerous phenomena associated with phreatomagmatic eruptions are dilute pyroclastic density currents (PDCs). These are turbulent, ground-hugging sediment gravity currents that travel radially away from the explosive center at up to 100 m/s. The Auckland Volcanic Field (AVF), New Zealand, consists of approximately 50 eruptive centers, at least 39 of which have had explosive phreatomagmatic behaviour. A primary concern for future AVF eruptions is the impact of dilute PDCs in and around the Auckland area. We combine field observations from the Maungataketake tuff ring, which has one of the best exposures of dilute PDC deposits in the AVF, with a quantitative model for flow of and sedimentation from a radially-spreading, steady-state, depth-averaged dilute PDC (modified from Bursik and Woods, 1996 Bull Volcanol 58:175-193). The model allows us to explore the depositional mechanisms, macroscale current dynamics, and potential impact on societal infrastructure of dilute PDCs from a future AVF eruption. The lower portion of the Maungataketake tuff ring pyroclastic deposits contains trunks, limbs and fragments of Podocarp trees (strength of the wood, we calculate that dynamic pressures (Pdyn) of 10-75 kPa are necessary to topple trees of this size and composition. Thus the two main criteria for model success based on the field evidence include (a) Pdyn must be >10 kPa nearer than 0.9 km to the vent, and 35 kPa can be expected within 3 km from source, ensuring complete destruction of the area; Pdyn > 15 kPa up to 5 km from source, resulting in heavy structural damage to most buildings and near destruction of weaker buildings; and Pdyn <10 kPa at ~6 km from source, resulting in severe damage to weaker structures at least up to this distance. This exercise illustrates our ability to combine field measurements with numerical techniques to explore controlling parameters of dilute PDC dynamics. These tools can be used to understand and estimate the damage potential and

  7. Experimental Determination of Bed Conditions in Concentrated Pyroclastic Density Currents

    Science.gov (United States)

    Winner, A.; Ferrier, K.; Dufek, J.

    2016-12-01

    Pyroclastic density currents (PDCs) are ground-hugging mixtures of hot gas and rock that can reach temperatures > 800 oC and speeds of 200 m/s. These flows are capable of eroding and entraining the underlying bed material into the flow, which can strongly influence flow momentum, runout distance, and hazards associated with PDCs. However, the mechanism of erosion remains poorly constrained, with proposed mechanisms including under-pressure following the head of the fluidized current, force chain enhanced stresses at the bed, and discrete particle impacts and friction. The interactions between PDCs and the bed have been difficult to observe in the field, as their infrequent occurrence, opacity, and hostile environment make real-time measurement difficult. This study is aimed at obtaining a better understanding of the interactions between PDCs and the bed through a quantitative analysis of bed forces. Our experimental apparatus consists of a rotating cylindrical flume of radius 22 cm, within which gas-rich granular material flows along the interior of the cylinder as it rotates. By using a rotating cylinder, we are able to simulate long-duration flows, allowing us to observe impact forces at the bed over timescales comparable to the flow duration of natural PDCs. To measure the distribution and evolution of forces imparted by the flow on the bed, we constructed a cylindrical insert with a non-erodible bed in which we embedded force sensor arrays parallel and perpendicular to the direction of flow. To measure the forces felt by the particles in the flow, we added "smart particles" 25 to 50 mm in diameter to the flow. Each smart particle contains a three-axis accelerometer and a micro SD card enclosed in a spherical plastic casing, and possesses a density similar to that of the pumice in the experimental flow. Each smart particle also contains a three-axis magnetometer which permits its location to be tracked by means of a unique applied magnetic field. Ultimately

  8. Assessment of Environmental Flows for the Rivers of Western Ganges Delta with Special Reference to Indian Sundarban

    Science.gov (United States)

    Bhadra, T.; Hazra, S.; Ghosh, S.; Barman, B. C.

    2016-12-01

    The Indian Sundarban, situated on the western tide-dominated part of the Ganges delta was formed by the sedimentation of the Ganges and its tributaries. Freshwater is a scarce resource in the Sundarban though it is traversed by rivers. Most of the rivers of Western Ganges Delta, which used to nourish the Sundarban, have become defunct with the passage of time. To ensure sustainable flow and to enhance the flow-dependent ecosystem services in this region, assessment of environmental flows within the system is required. A pilot assessment of environment flows, supported by IUCN has been carried out in some specific river reaches of Western Ganges Delta under the present study. The holistic Building Block Methodology (BBM) has been modified and used for the assessment of environmental flows. In the modified BBM, three distinctive blocks namely Hydro-Morphology, Ecology and Socio-Economy have been selected and indicators like Ganges Dolphin (Platanista gangetica), Sundari tree (Heritiera fomes) and Hilsa fish (Tenualosa ilisha) etc. have been determined to assess the environmental flows. As the discharge data of the selected rivers are restricted in the public domain, the SWAT model has been run to generate the discharge data of the classified rivers. The Hydraulic model, HEC-RAS has been calibrated in the selected River reaches to assess the habitat availability and its changes for indicator species under different flow condition. The study reveals that River Bhagirathi-Hugli requires 150-427 cumec additional water in monsoon and 850-1127 cumec additional water in post-monsoon months for Hilsa migration, whereas 327-486 cumec additional water in pre-monsoon and dry season and 227-386 cumec additional water in post-monsoon months are required for Dolphin movement. Flow requirement of river Ichhamati has also been estimated under the present study. The total required flow for the Sundarban ecosystem to reduce the salinity level from 30ppt to 14ppt during the dry and pre

  9. El nudo gordiano del régimen : Marcelo Caetano y la cuestión colonial

    Directory of Open Access Journals (Sweden)

    Josep Sánchez Cervelló

    2007-01-01

    Full Text Available Salazar y Caetano tuvieron plenos poderes para imponer su política colonial, pero no era posible parar el proceso descolonizador que sacudía el mundo y contra el cual no tenían ninguna política que no fuese la guerra y a ella se dedicaron con todas sus fuerzas pero fracasaron. La diferencia entre ambos presidentes del gobierno era que Caetano no solo supo que no podía ganar la guerra sino que tenía la certeza de que la perdería pero, al final, se mantuvo inflexible en la línea de conducta que consideraba era irrenunciable y que estaba en la base misma de la ideología del Estado Novo. Prefirió ser depuesto que acabar con la herencia secular de la Nación y después de haber dicho lo contrario, al final él también creyó que un Portugal sin las colonias se desnaturalizaría y, más pronto que tarde, comportaría la pérdida de la independencia y, aunque no lo dijese, estaba implícito, en ese pensamiento estratégico, el abrazo del oso español.Salazar and Caetano had full powers to impose their colonial policy, but it wasn’t possible to stop the decolonization process which was shaking the world .They had no policy but the war to which they devoted themselves although they failled. The difference between both presidents was that Caetano was sure that he was going to lose the war, nevertheless, he fought until the end because he thought that the colonization was the foundation of the Estado Novo’s ideology. He preferred to be demoted instead of finishing with the secular inheritance of the Nation because he was convinced that Portgual without colonies would become denaturalized and then it would lose its independence and, although he didn’t say it, the Spanish hug was implicit in that strategic thought In my opinion there was another problem: the Empire only could stay by means the dictatorship and, although the colonialism was widespread among Portuguese society, 13 years of war couldn’t have been suffered by a democratic

  10. Fiches pratiques: Fourchettes, et baguettes; La Revolution en mosaique; Bons Baisers, a bientot; Vieux Chat et jeune souris (Practical Ideas: Forks, and Bread; The Revolution in Mosaic; Hugs and Kisses, See You Later; Old Cat and Young Mouse).

    Science.gov (United States)

    Lauzeral, Isabelle; And Others

    1989-01-01

    Four classroom activities for French language instruction are described: an exercise focusing on differences in national cuisine and eating habits; a game about the French Revolution; analysis of and activities using a personal letter; and discussion based on a fable. (MSE)

  11. There’s a kind of hush…..

    Directory of Open Access Journals (Sweden)

    Yngve Nordkvelle

    2013-11-01

    masses”. Many, many other universities, world wide, are about to follow their example. Main universities, who traditionally have failed to take interest in provide mass education, are now, all of a sudden, at the front of “the development”.In the aftermath – or hush – second thoughts start to come to the fore. One of the main entrepreneurs of “MOOC”s, Sebastian Thrun, named “the Godfather” of MOOC, and CEO of Udacity, admits the failure of the project ran with San Jose State University. He blames the poor academic quality of the students for the failure. Rebecca Schuman, a widely acclaimed columnist and educational experts comments that the MOOCs seem to fail exactly the group of students who, allegedly, would benefit the most from this way of teaching and learning. This brings us all back to square one, and underlines what veterans in the field always have said. This is a difficult enterprise. There is no salvations provided by a new technology. I would like to add: thanks for the enthusiasm, and I look forward to what comes after “the hush”.In this issue we bring a new article from Professor Theo Hug from the University of Innsbruck, Austria. This is an analytical paper that provides us with profound perspectives about what communication related to teaching and learning with media is all about. It claims that when enthusiasts, such as the those providing MOOCs, go about and introduce new trends, they are often helpless in understanding the elementary dimension of media education, or the epistemological issues of the field. Hug sums up his contribution by arguing for polylogical design principles for an educational knowledge organization.In the paper by Michaela Rizzolli, also from the University of Innsbruck, Austria, we bring another contribution aiming at shedding light on the very foundations of media education. Ms. Rizzolli studies online playgrounds and introduces us to the problems we encounter when we stick to dichotomies in our thinking about this

  12. THE CITY- THE PORT-THE SEA The evolutive features of a complex relation

    Directory of Open Access Journals (Sweden)

    Mario Coletta

    2014-01-01

    Full Text Available The balanced relation between the city and the sea was at the centre of the Greek philosophy. During the flourishing of the Hellenic civilization, Plato began wondering about the appropriate characteristics of a site for an urban settlement near the sea. An ideal-type of urban settlement model resulted, based on accessibility, safety, hygienism, productivity, proximity to energy sources, prosperity.Renaissance artists appealed to the ancient knowledge in order to renew the treatises about architecture and town planning, in the perspective of building new models aiming at making perfect the structure and the soul of the city through a strictly geometric form.The harbour rose with open arms, towards the sea; a hug aiming at showing the pleasure of meeting,  guaranteeing shelter, protection, safety and friendly welcome.On the contrary, the harbour turns its back to the city and sometimes it moves the city away, in order to keep a certain distance.Physical and institutional barriers intervene between the city and the sea, claiming autonomous political-administrative and planning roles, often hindering, instead of fostering, natural osmotic processes, debasing functions, roles and social, economic, political and cultural interests of reciprocal belonging.Almost everywhere the legislative evolution has followed, and not preceded, the territorial devastation of settlements along the coasts – especially the devastation spontaneously risen – and only later has tried to hold in check a phenomenon sadly fallen in the ways of doing and the emptiness of thinking, letting the “habit of doing” prevail the conservative legislation based on placing pickets to the “not to do” approach; that situation in the light of an economic power become the director of political power, conditioned at opening eyes on doing for half-closing eyes on business.The new city-sea relation has to be studied as a valorisation, not as mere protective measures prescribed by

  13. Worldwide environmental impacts from the eruption of Thera

    Science.gov (United States)

    Lamoreaux, P. E.

    1995-10-01

    The eruptions of Thera (Santorini) between 1628 and 1450 BC constituted a natural catastrophe unparalleled in all of history. The last major eruption in 1450 BC destroyed the entire Minoan Fleet at Crete at a time when the Minoans dominated the Mediterranean world. In addition, there had to be massive loss of life from ejecta gases, volcanic ash, bombs, and flows. The collapse of a majestic mountain into a caldera 15 km in diameter caused a giant ocean wave, a tsunami, that at its source was estimated in excess of 46 m high. The tsunami destroyed ships as far away as Crete (105 km) and killed thousands of people along the shorelines in the eastern Mediterranean area. At distant points in Asia Minor and Africa, there was darkness from ash fallout, lightning, and destructive earthquakes. Earthquake waves emanating from the epicenter near the ancient volcano were felt as far away as the Norwegian countries. These disturbances caused great physical damage in the eastern Mediterranean and along the rift valley system from Turkey to the south into central Africa. They caused major damage and fires in north Africa from Sinai to Alexandria, Egypt. Volcanic ash spread upward as a pillar of fire and clouds into the atmosphere and blocked out the sun for many days. The ash reached the stratosphere and moved around the world where the associated gases and fine particulate matter impacted the atmosphere, soils, and waters. Ground-hugging, billowing gases moved along the water surface and destroyed all life downwind, probably killing those who attempted to flee from Thera. The deadly gases probably reached the shores of north Africa. Climatic changes were the aftermath of the eruption and the atmospheric plume was to eventually affect the bristlecone pine of California; the bog oaks of Ireland, England, and Germany, and the grain crops of China. Historical eruptions at Krakatau, Tambora, Vesuvius, and, more currently, eruptions at Nevado del Ruiz, Pinatubo, and Mount Saint

  14. Sedimentary processes and depositional environments of the Horn River Shale in British Columbia, Canada

    Science.gov (United States)

    Yoon, Seok-Hoon; Koh, Chang-Seong; Joe, Young-Jin; Woo, Ju-Hwan; Lee, Hyun-Suk

    2017-04-01

    The Horn River Basin in the northeastern British Columbia, Canada, is one of the largest unconventional gas accumulations in North America. It consists mainly of Devonian shales (Horn River Formation) and is stratigraphically divided into three members, the Muskwa, Otterpark and Evie in descending order. This study focuses on sedimentary processes and depositional environments of the Horn River shale based on sedimentary facies analysis aided by well-log mineralogy (ECS) and total organic carbon (TOC) data. The shale formation consists dominantly of siliceous minerals (quartz, feldspar and mica) and subordinate clay mineral and carbonate materials, and TOC ranging from 1.0 to 7.6%. Based on sedimentary structures and micro texture, three sedimentary facies were classified: homogeneous mudstone (HM), indistinctly laminated mudstone (ILM), and planar laminated mudstone (PLM). Integrated interpretation of the sedimentary facies, lithology and TOC suggests that depositional environment of the Horn River shale was an anoxic quiescent basin plain and base-of-slope off carbonate platform or reef. In this deeper marine setting, organic-rich facies HM and ILM, dominant in the Muskwa (the upper part of the Horn River Formation) and Evie (the lower part of the Horn River Formation) members, may have been emplaced by pelagic to hemipelagic sedimentation on the anoxic sea floor with infrequent effects of low-density gravity flows (turbidity currents or nepheloid flows). In the other hand, facies PLM typifying the Otterpark Member (the middle part of the Horn River Formation) suggests more frequent inflow of bottom-hugging turbidity currents punctuating the hemipelagic settling of the background sedimentation process. The stratigraphic change of sedimentary facies and TOC content in the Horn River Formation is most appropriately interpreted to have been caused by the relative sea-level change, that is, lower TOC and frequent signal of turbidity current during the sea

  15. Investigating the Grammatical and Pragmatic Origins of Wh-Questions in Children with Autism Spectrum Disorders

    Directory of Open Access Journals (Sweden)

    Manya Jyotishi

    2017-03-01

    Full Text Available Compared to typically developing children, children with autism (ASD show delayed production of wh-questions. It is currently controversial the degree to which such deficits derive from social-pragmatic requirements and/or because these are complex grammatical structures. The current study employed the intermodal preferential looking (IPL paradigm, which reduces social-pragmatic demands. The IPL paradigm can help distinguish these proposals, as successful comprehension promotes the “pragmatics-origins” argument whereas comprehension difficulties would implicate a “grammatical-origins” argument. Additionally, we tested both the linguistic and social explanations by assessing the contributions of children's early grammatical knowledge (i.e., SVO word order and their social-pragmatic scores on the Vineland to their later wh-question comprehension. Fourteen children with ASD and 17 TD children, matched on language level, were visited in their homes at 4-month intervals. Comprehension of wh-questions and SVO word order were tested via IPL: the wh-question video showed a costumed horse and bird serving as agents or patients of familiar transitive actions. During the test trials, they were displayed side by side with directing audios (e.g., “What did the horse tickle?”, “What hugged the bird?”, “Where is the horse/bird?”. Children's eye movements were coded offline; the DV was their percent looking to the named item during test. To show comprehension, children should look longer at the named item during a where-question than during a subject-wh or object-wh question. Results indicated that TD children comprehended both subject and object wh-questions at 32 months of age. Comprehension of object-wh questions emerged chronologically later in children with ASD compared to their TD peers, but at similar levels of language. Moreover, performance on word order and social-pragmatic scores independently predicted both groups' later

  16. COMPARISON OF Hα AND UV STAR FORMATION RATES IN THE LOCAL VOLUME: SYSTEMATIC DISCREPANCIES FOR DWARF GALAXIES

    International Nuclear Information System (INIS)

    Lee, Janice C.; Gil de Paz, Armando; Tremonti, Christy; Walter, Fabian; Kennicutt, Robert C.; Bothwell, Matthew; Johnson, Benjamin; Salim, Samir; Calzetti, Daniela; Dalcanton, Julianne; Dale, Daniel; Engelbracht, Chad; Funes, S. J. Jose G.; Sakai, Shoko; Skillman, Evan; Weisz, Daniel; Van Zee, Liese

    2009-01-01

    Using a complete sample of ∼300 star-forming galaxies within 11 Mpc of the Milky Way, we evaluate the consistency between star formation rates (SFRs) inferred from the far ultraviolet (FUV) non-ionizing continuum and Hα nebular emission, assuming standard conversion recipes in which the SFR scales linearly with luminosity at a given wavelength. Our analysis probes SFRs over 5 orders of magnitude, down to ultra-low activities on the order of ∼10 -4 M sun yr -1 . The data are drawn from the 11 Mpc Hα and Ultraviolet Galaxy Survey (11HUGS), which has obtained Hα fluxes from ground-based narrowband imaging, and UV fluxes from imaging with GALEX. For normal spiral galaxies (SFR ∼ 1 M sun yr -1 ), our results are consistent with previous work which has shown that FUV SFRs tend to be lower than Hα SFRs before accounting for internal dust attenuation, but that there is relative consistency between the two tracers after proper corrections are applied. However, a puzzle is encountered at the faint end of the luminosity function. As lower luminosity dwarf galaxies, roughly less active than the Small Magellanic Cloud, are examined, Hα tends to increasingly underpredict the total SFR relative to the FUV. The trend is evident prior to corrections for dust attenuation, which affects the FUV more than the nebular Hα emission, so this general conclusion is robust to the effects of dust. Although past studies have suggested similar trends, this is the first time this effect is probed with a statistical sample for galaxies with SFR ∼ sun yr -1 . By SFR ∼ 0.003 M sun yr -1 , the average Hα-to-FUV flux ratio is lower than expected by a factor of two, and at the lowest SFRs probed, the ratio exhibits an order of magnitude discrepancy for the handful of galaxies that remain in the sample. A range of standard explanations does not appear to be able to fully account for the magnitude of the systematic. Some recent work has argued for a stellar initial mass function which

  17. Editorial: Pedagogical Media Ecologies

    Directory of Open Access Journals (Sweden)

    Dorothee M. Meister

    2014-07-01

    learning and media ecologies with the material, global and ecological challenges that have become a part of the anthropocene. They do so by examining the mediation of a physical, architectural environment, their own departmental environment at Simon Fraser University. De Castell, Droumeva and Jenson uncover a range of practical and theoretical challenges, and explore the implications for both body and mind. Markus Deimann takes the reader back into the history of continental educational theory, to Humboldt’s (and others‘ expansive understanding of Bildung, to suggest a conceptual ecology germane to the manifold possibilities that are now on offer through open education. Deimann sees the «open paradigm» as changing education utterly – and for the better. It will do so, Deimann predicts, by «unbundling» resource and service provision, and assessment and accreditation functions that have for too long been monopolized by the educational monoliths known as «universities». Theo Hug’s contribution, «Media Form School – A Plea for Expanded Action Orientations and Reflective Perspectives» similarly looks to the past to envision possibilities for the future. Hug’s concern is with the narrow confines in which media are conceptualized and operationalized in many K-12 educational ecologies, and in the corresponding policy and curricular documents that further constrain and direct this action. Hug suggests looking to the recent past, the 1970s and 1960s, in which alternatives were envisioned not only by figures like McLuhan and Illich, but also intimated in the works of Austrian poets and artists. Norm Friesen provides the third «rearview mirror» perspective in his examination of the lecture as a trans-medial pedagogical form. From the late medieval university through to today’s IGNITE and TED talks, the lecture has accommodated and reflected a wide range of media ecologies, technical conditions and epistemological patterns. New media technologies –from the

  18. Comparisons of watershed sulfur budgets in southeast Canada and northeast US: New approaches and implications

    Science.gov (United States)

    Mitchell, M.J.; Lovett, G.; Bailey, S.; Beall, F.; Burns, D.; Buso, D.; Clair, T.A.; Courchesne, F.; Duchesne, L.; Eimers, C.; Fernandez, I.; Houle, D.; Jeffries, D.S.; Likens, G.E.; Moran, M.D.; Rogers, C.; Schwede, D.; Shanley, J.; Weathers, K.C.; Vet, R.

    2011-01-01

    Most of eastern North America receives elevated levels of atmospheric deposition of sulfur (S) that result from anthropogenic SO2 emissions from fossil fuel combustion. Atmospheric S deposition has acidified sensitive terrestrial and aquatic ecosystems in this region; however, deposition has been declining since the 1970s, resulting in some recovery in previously acidified aquatic ecosystems. Accurate watershed S mass balances help to evaluate the extent to which atmospheric S deposition is retained within ecosystems, and whether internal cycling sources and biogeochemical processes may be affecting the rate of recovery from decreasing S atmospheric loads. This study evaluated S mass balances for 15 sites with watersheds in southeastern Canada and northeastern US for the period 1985 to 2002. These 15 sites included nine in Canada (Turkey Lakes, ON; Harp Lake, ON; Plastic Lake, ON; Hermine, QC; Lake Laflamme, QC; Lake Clair, QC; Lake Tirasse, QC; Mersey, NS; Moosepit, NS) and six in the US (Arbutus Lake, NY; Biscuit Brook, NY; Sleepers River, VT; Hubbard Brook Experimental Forest, NH; Cone Pond, NH; Bear Brook Watershed, ME). Annual S wet deposition inputs were derived from measured bulk or wet-only deposition and stream export was obtained by combining drainage water fluxes with SO42- concentrations. Dry deposition has the greatest uncertainty of any of the mass flux calculations necessary to develop accurate watershed balances, and here we developed a new method to calculate this quantity. We utilized historical information from both the US National Emissions Inventory and the US (CASTNET) and the Canadian (CAPMoN) dry deposition networks to develop a formulation that predicted SO2 concentrations as a function of SO2 emissions, latitude and longitude. The SO2 concentrations were used to predict dry deposition using relationships between concentrations and deposition flux derived from the CASTNET or CAPMoN networks. For the year 2002, we compared the SO2

  19. A closer look at the pyroclastic density current deposits of the May 18, 1980 eruption of Mt St Helens

    Science.gov (United States)

    Mackaman-Lofland, C. A.; Brand, B. D.; Dufek, J.

    2010-12-01

    Pyroclastic Density Currents (PDCs) are the most dangerous hazard associated with explosive volcanic eruptions. Due to the danger associated with observing these ground-hugging currents of searing hot gas, ash, and rock in real time, their processes are poorly understood. In order to understand flow dynamics, including what controls how far PDCs travel and how they interact with topography, it is necessary to study their deposits. The May 18th, 1980 eruption of Mt. St. Helens produced multiple PDCs, burying the area north of the volcano under 10s of meters of PDC deposits. Because the eruption is one of the best observed on record, individual flow units can be correlated to changes in eruptive intensity throughout the day (e.g., Criswell, 1987). Deep drainage erosion over the past 30 years has exposed the three-dimensional structure of the PDC deposits, making this intensive study possible. Up to six flow units have been identified along the large western drainage of the pumice plain. Each flow unit has intricate vertical and lateral facies changes and complex cross-cutting relationships away from source. The most proximal PDC deposits associated with the afternoon flows on May 18 are exposed 4 km from source in tributaries of the large drainage on the western side of the pumice plain. Hummocks from the debris avalanche are also exposed above and within these proximal drainages. It is apparent that the PDCs were often erosional, entraining large blocks from the hummocks and depositing them in close proximity downstream. The currents were also depositional, as thick sequences of PDC deposits are found in areas between hummocks, which thin to veneers above them. This indicates that the currents were interacting with complex topography early in their propagation, and is reflected by spatially variable bed conditions including rapid changes in bedding and granulometry characteristics within individual flow units. For example, within 20 lateral meters of a given flow

  20. The role of a therapeutic team and The Pol-Ilko Association in readaptation of patients with a stoma to the life in a family and society in the 21st century.

    Science.gov (United States)

    Snarska, J; Lapuc, K; Puchalski, Z; Hend, M

    2005-01-01

    Patients who crossed operation where exteriorization stoma was integral her part the aside from of cause, location and far-gone of illness which hereinto brought require special care. In moment of entry we to European Union should advert on introduction by us the surgeons of new operating techniques not only, but to attach importance to quality of sick's life after operations also, particularly these which violate beauty of our body. They are of the patients' groups the nation from stoma, particularly if cause the exteriorization stoma the state the neoplasmic disease of alimentary canal or arrangement urinary. The stay in Clinic whether the surgical squad, perspective of operation which is final effect producing artificial accompanying urinary content tract intestinal or fecal it joins with high-level of phobia. The Information Bureau for Stoma in year 1993 at Medical University was created and on the basis of this the information bureau the therapeutic complex worked out own model of these patients' care over group. The model of care over sick from stomy hugs three periods: preoperative, early and late surgical period (ambulant). On the basis of The Information Bureau from Stoma in 1994 year The Department was created of Podlasie the Society of Care over Patients from Stoma in Bialystok--association of working on thing sick's good. Organization this assembles from stomy the men, their family and guardians, workers of medical service and different men of good will. Meetings are forms of working, which performance of bothering patient's problems connected with nurturing and supply stomy is aim, and also psychical and help support in readaptation to life in family, company and society. The volunteers' training is to help different form of working this sick's group. Volunteer in this case--then living from stomy over year happily, adopted to life in every respect, person which exemplifies for sick prepared to operation positive (exteriorization stoma) or beginning

  1. Grp78 promotes the invasion of hepatocellular carcinoma

    International Nuclear Information System (INIS)

    Su, Rongjian; Li, Zhen; Li, Hongdan; Song, Huijuan; Bao, Cuifen; Wei, Jia; Cheng, Liufang

    2010-01-01

    Glucose regulated protein 78 (Grp78) is involved in the invasion and metastasis in many human cancers including gastric cancer, breast cancer, prostate cancer. But the role of Grp78 in the invasion of human hepatocellular carcinoma has not been reported. In this article, we examined if Grp78 was associated with the invasion of hepatocellular carcinoma and explored the possible underlying mechanism. The Grp78 and FAK expression levels in 44 patients with hepatocellular carcinoma were examined using immunohistochemistry. Grp78 overexpressing SMMC7721 cells were established by pcDNA3.1 (+)-Grp78 transfection and screened by G418. Grp78 and FAK levels in Grp78 overexpressing cells were down-regulated by siRNA transfection. The invasion status of tumor cells was evaluated by transwell assay in vitro, and chick embryo metastasis model in vivo. Cell spreading was determined by cell spreading assay, and quantitatively measured by Orisis software HUG. Grp78, pY397 FAK, pY576/577 FAK and FAK levels were detected by western blot. RhoA activity was detected by GST pulldown assay. The distribution of actin cytoskeleton was observed by fluorescent staining. Grp78 expression levels in 44 patients with hepatocellular carcinoma were negatively correlated with tumor grading, and positively correlated with portal invasion and intra-hepatic invasion. Overexpression of Grp78 in SMMC7721 cells promoted the invasion of cancer cells in vitro and in vivo, and this increase in tumor cell invasion was blocked by Grp78 siRNA knockdown. Our results also revealed that overexpression of Grp78 in SMMC7721 cells accelerated the process of cell spreading and promoted lamellipodia formation. Further analysis showed that overexpression of Grp78 in SMMC7721 cells increased pY397 and pY576/577 levels of FAK. Grp78 siRNA knockdown decreased FAK activation and activity. Our results also revealed that Grp78 overexpression in SMMC7721 cells decreased RhoA-GTP level, and Grp78 siRNA knockdown rescued Rho

  2. Grp78 promotes the invasion of hepatocellular carcinoma

    Directory of Open Access Journals (Sweden)

    Li Hongdan

    2010-01-01

    Full Text Available Abstract Background Glucose regulated protein 78 (Grp78 is involved in the invasion and metastasis in many human cancers including gastric cancer, breast cancer, prostate cancer. But the role of Grp78 in the invasion of human hepatocellular carcinoma has not been reported. In this article, we examined if Grp78 was associated with the invasion of hepatocellular carcinoma and explored the possible underlying mechanism. Methods The Grp78 and FAK expression levels in 44 patients with hepatocellular carcinoma were examined using immunohistochemistry. Grp78 overexpressing SMMC7721 cells were established by pcDNA3.1 (+-Grp78 transfection and screened by G418. Grp78 and FAK levels in Grp78 overexpressing cells were down-regulated by siRNA transfection. The invasion status of tumor cells was evaluated by transwell assay in vitro, and chick embryo metastasis model in vivo. Cell spreading was determined by cell spreading assay, and quantitatively measured by Orisis software HUG. Grp78, pY397 FAK, pY576/577 FAK and FAK levels were detected by western blot. RhoA activity was detected by GST pulldown assay. The distribution of actin cytoskeleton was observed by fluorescent staining. Results Grp78 expression levels in 44 patients with hepatocellular carcinoma were negatively correlated with tumor grading, and positively correlated with portal invasion and intra-hepatic invasion. Overexpression of Grp78 in SMMC7721 cells promoted the invasion of cancer cells in vitro and in vivo, and this increase in tumor cell invasion was blocked by Grp78 siRNA knockdown. Our results also revealed that overexpression of Grp78 in SMMC7721 cells accelerated the process of cell spreading and promoted lamellipodia formation. Further analysis showed that overexpression of Grp78 in SMMC7721 cells increased pY397 and pY576/577 levels of FAK. Grp78 siRNA knockdown decreased FAK activation and activity. Our results also revealed that Grp78 overexpression in SMMC7721 cells decreased

  3. A combined field and numerical approach to understanding dilute pyroclastic density current dynamics and hazard potential: Auckland Volcanic Field, New Zealand

    Science.gov (United States)

    Brand, Brittany D.; Gravley, Darren M.; Clarke, Amanda B.; Lindsay, Jan M.; Bloomberg, Simon H.; Agustin-Flores, Javier; Németh, Károly

    2014-04-01

    The most dangerous and deadly hazards associated with phreatomagmatic eruptions in the Auckland Volcanic Field (AVF; Auckland, New Zealand) are those related to volcanic base surges - dilute, ground-hugging, particle laden currents with dynamic pressures capable of severe to complete structural damage. We use the well-exposed base surge deposits of the Maungataketake tuff ring (Manukau coast, Auckland), to reconstruct flow dynamics and destructive potential of base surges produced during the eruption. The initial base surge(s) snapped trees up to 0.5 m in diameter near their base as far as 0.7-0.9 km from the vent. Beyond this distance the trees were encapsulated and buried by the surge in growth position. Using the tree diameter and yield strength of the wood we calculate that dynamic pressures (Pdyn) in excess of 12-35 kPa are necessary to cause the observed damage. Next we develop a quantitative model for flow of and sedimentation from a radially-spreading, dilute pyroclastic density currents (PDCs) to determine the damage potential of the base surges produced during the early phases of the eruption and explore the implications of this potential on future eruptions in the region. We find that initial conditions with velocities on the order of 65 m s- 1, bulk density of 38 kg m- 3 and initial, near-vent current thicknesses of 60 m reproduce the field-based Pdyn estimates and runout distances. A sensitivity analysis revealed that lower initial bulk densities result in shorter run-out distances, more rapid deceleration of the current and lower dynamic pressures. Initial velocity does not have a strong influence on run-out distance, although higher initial velocity and slope slightly decrease runout distance due to higher rates of atmospheric entrainment. Using this model we determine that for base surges with runout distances of up to 4 km, complete destruction can be expected within 0.5 km from the vent, moderate destruction can be expected up to 2 km, but much

  4. Temple Grandin e o autismo: uma análise do filme Temple Grandin and autism: the film review

    Directory of Open Access Journals (Sweden)

    Carlo Schmidt

    2012-06-01

    categorical and dimensional diagnosis of autism are discussed, as well as confusion related to classification issues. The historical notion that people with autism are always highly intelligent is reviewed, proposing deconstruction of this stereotype by understanding the presence of special abilities within the scope of what cognitive theorists call different cognitive styles. Sensory disturbance in autism is also addressed, such as those that drive Temple to develop the hug machine to help other autistic people to deal with interpersonal difficulties, which were often mistaken for lack of affective expression. Finally, the correlations between quality of parenting and autism are discussed, based upon scenes in the film. The aim is not to exhaust the subject in a thorough and extensive analysis, but rather to provide theoretical understanding of the work.

  5. MicroCT vs. Hg porosimetry: microporosity in commercial stones

    Science.gov (United States)

    Fusi, N.; Martinez-Martinez, J.; Barberini, V.; Galimberti, L.

    2009-04-01

    dolomite). In some cases microporosity coincide with structural features of the rock, such as stylolythes (CV), fissures (AT) and veins (RC). This method works for samples with low porosity (less than 1%); on the other hand for samples with higher porosity (4%; A and BS) microCT images after Hg saturation present artefacts, due to the spreading of Hg within the sample, which obliterates the true structure of the rock. References Klobes, P., Riesemeier, H., Meyer, K., Goebbles, J. and Hellmuth, K.H. (1997). Rock porosity determination by combination of K-ray computerized tomography with mercury porosimetry. Fresenius J. Anal. Chem., 357, 543-547 Lin-Gibson, S., Cooper, J.A., Forrest, A.L. and Cicerone, M.T. (2007). Systematic investigation of porogen size and content on scaffold morphometric parameters and properties. Biomacromolecules, 8, 1511-1518.

  6. On the interaction between fluid turbulence and particle loading: numerical simulation of turbidity currents and prediction of deep-sea arenites

    Science.gov (United States)

    Doronzo, D. M.; Dufek, J.

    2012-04-01

    calculated with a two-equation model (RNG k-ɛ) solving for the turbulent kinetic energy and the turbulent dissipation rate. The simulated seafloor is represented by a ramp 8 km long and 3° steep, over which the particles rebound inelastically, in order to capture the bed-load of the current. Although the sediment is mainly transported as suspended-load (this makes the flow "turbid"), the ground-hugging processes play a fundamental role in the emplacement of deposits, as well as in the flow behavior. A highly refined grid of 0.2 m at the base is thus used to solve for these processes. After 6750 s of flow time, sedimentation rates of 4 and 0.5 kg/m2 s are calculated over the seafloor in proximal (1 km) and medial (4 km) regions, respectively. These values are converted to deposit thickness, resulting in arenitic turbidite sequences of 14.5 and 1.8 m, respectively. Turbulence intensities of 54 and 66 %, respectively in the same areas, indicate the water is further made turbulent by the sediment (water-sand interaction), so the sand moves in suspension toward the deep-sea, where is able to deposit. Richardson numbers of 0.79 and 0.58, respectively, show how the water entrainment in the current increases with distance.

  7. Laser Induced Fluorescence Imaging: Searching for Organics from the Dry Valleys of Queen Maud Land Antarctica to the Regolith and Ices of Mars

    Science.gov (United States)

    Storrie-Lombardi, M. C.; Sattler, B.; Muller, J.-P.; Fisk, M.; Cousins, C.; Dartnell, L.

    2009-04-01

    Laser induced fluorescence imaging using excitation in ultraviolet (UV) wavelengths has been proposed as a nondestructive astrobiological rapid survey tool to search for amino and nucleic acids [1], microbial life [2], and polycyclic aromatic hydrocarbons (PAHs) deep in the Mars regolith [3, 4]. However, the technique is easily adapted to search for complex biomolecular targets using longer wavelength sources [5]. Of particular interest is the ability of excitation at 532 nm to detect photosynthetic pigments in cyanobacteria-dominated microbial communities populating the ice of alpine, Arctic, and Antarctic lakes, glaciers, and ice sheets [6-8]. During the months of November and December 2008 we tested the technique as part of an extended international, interdisciplinary field campaign in the Dry Valleys of Schirmacher Oasis and Lake Untersee, Queen Maud Land, Antarctica. In this paper we review our recent laboratory experiments on the use of UV excitation for detection of PAHs doped on Mars analogue soils [9] and chasmo- and epilithic lichen communities within basaltic Iceland lavas. We present for the first time the results of our field experiments conducted during the Tawani 2008 International Antarctic Expedition for in situ detection and quantification of photosynthetic biomass in the ice caps of annual and perennially ice-covered Antarctic lakes. We discuss the advantages of using a nondestructive rapid survey photonic tools such as laser induced fluorescence imaging that can be easily implemented from lander, rover, airborne, or orbital platforms. The techniques presented can be utilized to monitor the microbial potential of large, critical ecosystems on Earth, or to facilitate the remote or manned search for organics and photosynthetic life on any terrestrial planet. References 1. Storrie-Lombardi, M.C., Hug, W.F., McDonald, G.D., Tsapin, A.I., and Nealson, K.H. 2001. Hollow cathode ion lasers for deep ultraviolet Raman spectroscopy and fluorescence imaging

  8. New morphological mapping and interpretation of ejecta deposits from Orientale Basin on the Moon

    Science.gov (United States)

    Morse, Zachary R.; Osinski, Gordon R.; Tornabene, Livio L.

    2018-01-01

    stage of crater formation - and flowed and ponded in topographically low-lying regions. Facies E consists of distinct crater chains emanating radially from the basin center and extending from ∼700 to ∼1000 km from the center of Orientale. This facies is considered to be chains of secondary craters formed from large blocks of ballistic ejecta. Our mapping effort shows that the individual ejecta facies were influenced and controlled to varying degrees by pre-existing slopes and topography. At the basin scale, the overall downslope direction toward the lunar lowlands to the east and southeast of the basin center resulted in large impact melt flows 100's of kilometers in length, while the regional upslope trends in the west and northwest inhibited the development of extensive impact melt flows. On a smaller scale it can be observed that ground-hugging ejecta collected behind and flowed around high topographic obstacles while diverting into topographic low regions (e.g., around uplifted pre-existing crater rims, but down into pre-existing crater floors). The dispersion of the various ejecta facies mapped here also indicates both a direction and an angle for the impact event that formed Orientale Basin. The bilateral distribution of both ballistic and impact melt-rich ejecta deposits across a line running northeast - southwest suggests the impact occurred from the northeast toward the southwest. Careful mapping of the secondary impact crater chains (Facies E) shows the development of a ;forbidden zone; lacking these impacts to the northeast as well as a concentration of the longest secondary crater chains to the northwest and southeast, perpendicular to the aforementioned line of bilateral ejecta distribution. This distribution of secondary impact craters contrasts with the circularity of the basin and suggests that Orientale Basin was formed by ∼ 25-45° impact from the northeast.

  9. People

    Science.gov (United States)

    2001-09-01

    teachers in Iceland and on Friday to teachers in Ireland. Fred and Frances from Southgate College showed great team spirit in the world's most chaotic quiz, then sang in harmony with Dave from Barnsley and Yoji from Japan amongst others. Kirsten from across the Atlantic shared her research on children and museums on Friday and later I discovered how much I didn't know about global warming from a chemist and a set of unreadable graphs in a computer lab. What a pleasure to see Tom and Seamus from Ireland again. The day closed with a barn dance fling where I managed to boogie on down with some teachers from Turkey. A final 'strip the willow' with Pete and Allison finished me off. Saturday started with breakfast with Ken from Greenwich offering me some part-time work. The exhibitions called and amongst others I hugged Sue from Cardiff, Barry and Leila from London, Pauline from Scotland and an unknown but very friendly lady from Holland. I met a lady from Scotland who lived in Iceland but who taught in Norway and of course Catherine was everywhere. I had tea with Jean from Edinburgh, Janet from London, Gordon from Aberdeen. I laughed with Mick from Sheffield and the same friendly lady from Holland. I ate posh food with Susie from Ayr and applauded big names from America and Australia. I shared a lump in my throat for John and for Wynne and nodded and smiled at countless people whose names I had forgotten but our paths had crossed sometime in the past. There are more than 20 000 members in the ASE and countless thousands of science teachers across the globe. The world is indeed expansive but for three days in Guildford it seemed that the very best speakers and the very cheeriest folk had magically converged on one place. If ever there were confirmation that science and science teaching were alive and well it was there and it was then. If you were there you will know exactly what I mean. If you weren't there then don't miss it next January in Liverpool.www.ase.org.uk

  10. Toward an integrated genetic model for vent-distal SEDEX deposits

    Science.gov (United States)

    Sangster, D. F.

    2018-04-01

    Although genetic models have been proposed for vent-proximal SEDEX deposits, an equivalent model for vent-distal deposits has not yet appeared. In view of this, it is the object of this paper to present a preliminary integrated vent-distal genetic model through exploration of four major components: (i) nature of the ore-forming fluid, (ii) role of density of the unconsolidated host sediments, (iii) dynamics of sulfate reduction and (iv) depositional environment. Two sub-groups of SEDEX Pb-Zn deposits, vent-proximal and vent-distal, are widely recognized today. Of the two, the latter is by far the largest in terms of metal content with each of the 13 largest containing in excess of 7.5 M (Zn+Pb) metal. In contrast, only one vent-proximal deposit (Sullivan) falls within this size range. Vent-proximal deposits are characteristically underlain by local networks of sulfide-filled veins (commonly regarded as feeder veins) surrounded by a discordant complex of host rock alteration. These attributes are missing in vent-distal deposits, which has led to the widespread view that vent-distal ore-forming fluids have migrated unknown distances away from their vent sites. Because of the characteristic fine grain size of ore minerals, critical fluid inclusion data are lacking for vent-distal ore-stage sulfides. Consequently, hypothetical fluids such as those which formed MVT deposits (120 °C, 20% NaCl equiv.) are considered to represent vent-distal fluids as well. Such high-salinity fluids are capable of carrying significant concentrations of Pb and Zn as chloride complexes while the relatively low temperatures preclude high Cu contents. Densities of such metalliferous brines result in bottom-hugging fluids that collect in shallow saucer-shaped depressions (collector basins). Lateral metal zoning in several deposits reveals the direction from which the brines came. Relative densities of the ore-forming fluid and sediment determine whether the ore-forming fluid stabilizes on top

  11. Editorial: Vada a bordo

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    Yngve Nordkvelle

    2012-11-01

    develop courage and judgement in students to cope with uncertainness and conflicts in the supercomplex society:The student’s being has to take centre stage. Feeling uncertainty, responding to uncertainty, gaining confidence to insert oneself amid the numerous counter-claims to which one is exposed, engaging with the enemy, and developing resilience and courage: these are matters of being. Their acquisition calls for a revolution in the pedagogical relationships within a university. (Barnett 2000, s.170-171.Please, politicians for higher education, “VADA A BORDO!”The PapersIn this issue we bring five articles – a Russian and German paper, one Austrian, one Danish and Swedish, one Danish and a Norwegian paper. In diverse ways they all address concerns that relate to changes in knowing and how knowledge is acquired.Thommy Eriksson, of  Chalmers University of Technology, Sweden, and Inge Ejby Sørensen, of Copenhagen University, are both bold pioneers in their diligent work presented in the paper “Reflections on academic video”. Their ambition is to establish an academic journal for visual publications, predominantly videos. They present us for the paradox that a substantial number of academics teach visual subjects, video analysis and video production, and yet rarely disseminate and mediate via audiovisual media. They argue that documentary theory and semiotics are two critical traditions in academia that will provide the conventional credentials for establishing a new academic genre. In the journal “Audiovisual thinking” we can follow an exciting new and path breaking way of academic discourse.In the paper “Storytelling – EDU: Educational – Digital – Unlimited? Theo Hug of the University of Innsbruck,  raises the question of “Digital Storytelling” as a genre for educational purposes. He acknowledges that students are often very competent in using media and are well prepared to go beyond “writing” as a monomedial activity. The paper reflects

  12. Reconocimiento alogénico: su papel protector durante la infección por el virus de la inmunodeficiencia humana tipo1 (VIH-1

    Directory of Open Access Journals (Sweden)

    María Teresa Rugeles López

    2004-03-01

    terapia antirretroviral.

     

    REFERENCIAS

    1. LEHNER T, SHEARER GM, HACKETT CJ, SCHULTZ A and SHARMA OK. Alloimmunization as a strategy for vaccine design against HIV/AIDS. AIDS Res Hum Retroviruses 2000; 16: 309-313

    2. MACDONALD KS, EMBREE J, NJENGA S, NAGELKERKE NJ, NGATIA I, MO- HAMMED Z, et al. Mother-child class I HLA concordance increases perinatal human immunodeficiency virus type 1 transmission. J Infect Dis 1998; 177: 551-556.

    3. The International Perinatal HIV Group. The mode of delivery and the risk of vertical transmission of human immunodeficiency virus type 1 – a meta-analysis of 15 prospective cohort studies. New Engl.J. Med. 1999; 340: 977–987

    4. CLERICI M. Cell-mediated immunity in HIV infection. AIDS 1993; 7 (Suppl 1: S135–S140

    5. PATTERSON BK, BEHBAHANI H, KABAT W, SULLIVAN Y, O’GORMAN MR, LANDAY A, et al. Leukemia inhibitory factor inhibits HIV-1 replication and is upregulated in placentae from nontransmitting women. J. Clin. Invest. 2001; 107: 287–294

    6. BOURINBAIAR AS and LEE-HUANG S. Anti-HIV effect of b subunit of human chorionic gonadotropin (b hCG in vitro. Immunol. Lett. 1995; 44: 13–18

    7. COULOMB-L’HERMIN A, AMARA A, SCHIFF C, BURANDGASSELIN I, FOUSSAT A, DELAUNEY T, et al. Stromal cellderived factor 1 (SDF-1 and antenatal human B cell lymphopoiesis: expression of SDF-1 by

  13. Digital Storytelling – Special issue

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    Yngve Nordkvelle

    2010-11-01

    Wiesinger et al. We think, however, that an exploration of a more multimedial approach to dissemination of research in the field is needed. With this in mind, we believe that “Seminar.net”, unhampered by many of the limits of the medium of paper, offers an opportunity to express a richer account of the field. We have encouraged the authors to provide presentations that use digital stories as examples, demonstrations, and expositions, while maintaining certain traditional academic elements, such as an abstract and references. We hope the readers will appreciate the variety of genres that support the ordinary textual information of this journal. All contributions have been peer-reviewed by independent reviewers, who are selected among members of our editorial board, and an expert panel. The less conventional papers have been selected to fit in with our section of “Practical papers”. We consider these papers of high practical merit. We thank Joe Lambert of the Center for Digital Storytelling, professor Theo Hug of University of Innsbruck, and professor Knut Lundby, University of Oslo who have acted as an advisory board to the editors for this special issue. They have provided us with access to their networks, assisted in attracting good reviewers and responded to our practical and principal questions along the way to publishing.Teaching and learning with Digital StorytellingMonica Nilsson, at the University of Stockholm, discusses digital storytelling in this article. A digital story is defined as a multimodal narrative text comprising  pictures, music, speech, sound and script.  In the article she describes and analyzes a nine year old boy´s digital stories and argues that new media, here as digital storytelling, has the potential to play a significant role in the development of both literacy and creativity.Grete Jamissen and Goro Skou work at the University College of Oslo. In their article, “ Poetic reflection through digital storytelling – a methodology to