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Sample records for hematology analyzer stand-alone

  1. Analyzing grid extension and stand-alone photovoltaic systems for the cost-effective electrification of Kenya

    Zeyringer, Marianne; Pachauri, Shonali; Schmid, Erwin; Schmidt, Johannes; Worrell, Ernst|info:eu-repo/dai/nl/106856715; Morawetz, Ulrich B.

    2015-01-01

    The declaration of 2014-2024 as the Decade of Sustainable Energy for All has catalyzed actions towards achieving universal electricity access. The high costs of building electric infrastructure are a major impediment to improved access, making stand-alone photovoltaic (PV) systems an attractive

  2. Stand-alone XLIF

    Hansen, E. J.; Simony, A.; Hummel, Stefan

    2015-01-01

    and clinical/radiological results in 22 patients treated with XLIF procedure for DS or degenerative disc disease (DDD). Material and methods: 22 consecutive patients with DS underwent surgery with the XLIF stand-alone procedure, with follow-up of 24 months. Clinical outcome scores were collected. Complications......Introduction: Adult thoracolumbar degeneration is an increasing challenge in the aging population. With age the progressive degeneration of the discs leads to an asymmetric collapse and a thoracolumbar coronal plane deformity, a degenerative scoliosis (DS). Aim: To evaluate the complication rate......-year follow-up, with a 31.8% revision rate. Due to the high revision rate we recommend supplementary posterior instrumentation, to achieve a higher fusion rate. When considering XLIF-stand-alone procedure for DS or DDD without supplemental posterior instrumentation, only single-level disease should...

  3. CANGS DB: a stand-alone web-based database tool for processing, managing and analyzing 454 data in biodiversity studies

    Schlötterer Christian

    2011-06-01

    Full Text Available Abstract Background Next generation sequencing (NGS is widely used in metagenomic and transcriptomic analyses in biodiversity. The ease of data generation provided by NGS platforms has allowed researchers to perform these analyses on their particular study systems. In particular the 454 platform has become the preferred choice for PCR amplicon based biodiversity surveys because it generates the longest sequence reads. Nevertheless, the handling and organization of massive amounts of sequencing data poses a major problem for the research community, particularly when multiple researchers are involved in data acquisition and analysis. An integrated and user-friendly tool, which performs quality control, read trimming, PCR primer removal, and data organization is desperately needed, therefore, to make data interpretation fast and manageable. Findings We developed CANGS DB (Cleaning and Analyzing Next Generation Sequences DataBase a flexible, stand alone and user-friendly integrated database tool. CANGS DB is specifically designed to organize and manage the massive amount of sequencing data arising from various NGS projects. CANGS DB also provides an intuitive user interface for sequence trimming and quality control, taxonomy analysis and rarefaction analysis. Our database tool can be easily adapted to handle multiple sequencing projects in parallel with different sample information, amplicon sizes, primer sequences, and quality thresholds, which makes this software especially useful for non-bioinformaticians. Furthermore, CANGS DB is especially suited for projects where multiple users need to access the data. CANGS DB is available at http://code.google.com/p/cangsdb/. Conclusion CANGS DB provides a simple and user-friendly solution to process, store and analyze 454 sequencing data. Being a local database that is accessible through a user-friendly interface, CANGS DB provides the perfect tool for collaborative amplicon based biodiversity surveys

  4. Solar Charged Stand Alone Inverter

    M.Vasugi; Prof R.Jayaraman

    2014-01-01

    This paper deals with solar powered stand alone inverter which converts the variable dc output of a photovoltaic solar panel into ac that can be fed to loads. Stand alone inverters are used in systems where the inverter get its energy from batteries charged by photo voltaic arrays. A charge controller limits the rate at which electric current is added to or drawn from electric batteries. This charge discharge controller is needed to prevent the battery from being overcharged o...

  5. The Stand-alone Heliostat

    Garcia Navajas, G. I.; Egea Gea, A.

    2000-01-01

    The first Autonomous Heliostat has been developed by CIEMAT at PSA facilities in Almeria. This heliostat is an innovative approach to reducing the civil engineering work costs in heliostat fields of central tower plants. Channels, cables and other electric elements have been eliminated in the new heliostat. Thus, one 70-nr, classical T glass/metal heliostat has been adapted to include all the new stand-alone concept components. A PV system is able to drive two sun-tracking DC motors between 5 and 24Vdc, 0 and 15A. The heliostat communicates with the control room 400-m away by using a radio-modem working at 9600 baud. An anemometer, a wind switcher, light and ambient temperature sensors have been installed on the heliostat for self-protection decision-making. A PV panel integrated into the heliostat reflecting surface, eliminates cabling and other elements required for a conventional power supply. Communication lines between master control and local control have been replaced by radio-modem. Testing has validated the technical feasibility of the prototype and quantified the real consumption and efficiencies of new elements. The extra costs produced.by the autonomous concepts are compared with the cost of civil work in conventional heliostat field. (Author) 8 refs

  6. Basic Stand Alone Medicare Inpatient Claims PUF

    U.S. Department of Health & Human Services — This release contains the Basic Stand Alone (BSA) Inpatient Public Use Files (PUF) named CMS 2008 BSA Inpatient Claims PUF with information from 2008 Medicare...

  7. Basic Stand Alone Carrier Line Items PUF

    U.S. Department of Health & Human Services — This release contains the Basic Stand Alone (BSA) Carrier Line Items Public Use Files (PUF) with information from Medicare Carrier claims. The CMS BSA Carrier Line...

  8. Stand alone photovoltaic systems: guarantee of results

    NONE

    1996-12-31

    This study aims to provide a guarantee of results for system performance for users of stand-alone photovoltaic (PV) systems, which have no back-up generator. The appropriate main performance criterion for PV systems is that a specified load is supplied with power either continuously or intermittently whenever the load requires power. A methodology to evaluate the power availability of stand-alone PV systems has been developed as part of the project, which encompasses power losses due to weather variations. The guarantee of results produced allows users to compare system designs from different manufacturers. (UK)

  9. Verification and quality control of routine hematology analyzers

    Vis, J Y; Huisman, A

    2016-01-01

    Verification of hematology analyzers (automated blood cell counters) is mandatory before new hematology analyzers may be used in routine clinical care. The verification process consists of several items which comprise among others: precision, accuracy, comparability, carryover, background and

  10. Stand-alone photovoltaic applications. Lessons learned

    Loois, G.; Van Hemert, B.

    1999-02-01

    The IEA Photovoltaic Power Systems Programme (PVPS) is one of the collaborative R and D agreements established within the IEA. The objective of Task III is to promote and facilitate the exchange of information and experiences in the field of PV Systems in Stand-alone and Island Applications (SAPV). The book focuses on the practical experiences gained, and does not aim to provide a complete manual on SAPV. When Task III started its activities in 1993, a collection of 50 'State of the art' projects was published in the book 'Examples of Stand-Alone Photovoltaic Systems'. This publication marked the base line for the work of the task. Now, in 1998, the showcases from each country demonstrate the lessons learned in five years of cooperation. The book consists of two parts. The first part contains eight chapters dealing with a specific aspect of stand-alone PV. The second part introduces 14 national showcase projects in a systematic presentation. Each chapter and showcase can be read independently from the rest of the book. Chapter 2, contributed by The Netherlands, analyses the market for stand-alone PV systems. It gives an overview of the 'traditional' application of stand-alone PV, which is the electrification of remote buildings and which has been addressed in depth in other publications. The focus is on the market niches of service applications that are also interesting for more densely populated areas, e.g. in industrialised countries. The United Kingdom illustrates the economic aspects in Chapter 3. Cost comparisons are made, but more important is the illustration of the non-financial considerations that make PV the preferred choice as a power source for many applications. Switzerland explores in Chapter 4 (financing aspects) different financing mechanisms, and financial policies used to overcome the initial cost barrier. Most of these approaches have been applied in developing countries rather than in the western world. Using various examples from all over the

  11. Verification and quality control of routine hematology analyzers.

    Vis, J Y; Huisman, A

    2016-05-01

    Verification of hematology analyzers (automated blood cell counters) is mandatory before new hematology analyzers may be used in routine clinical care. The verification process consists of several items which comprise among others: precision, accuracy, comparability, carryover, background and linearity throughout the expected range of results. Yet, which standard should be met or which verification limit be used is at the discretion of the laboratory specialist. This paper offers practical guidance on verification and quality control of automated hematology analyzers and provides an expert opinion on the performance standard that should be met by the contemporary generation of hematology analyzers. Therefore (i) the state-of-the-art performance of hematology analyzers for complete blood count parameters is summarized, (ii) considerations, challenges, and pitfalls concerning the development of a verification plan are discussed, (iii) guidance is given regarding the establishment of reference intervals, and (iv) different methods on quality control of hematology analyzers are reviewed. © 2016 John Wiley & Sons Ltd.

  12. Developing a mobile stand alone photovoltaic generator

    Soler-Bientz, R.; Ricalde-Cab, L.O.; Solis-Rodriguez, L.E.

    2006-01-01

    This paper describes a recent work developed to create a mobile stand alone photovoltaic generator that can be easily relocated in remote areas to evaluate the feasibility of photovoltaic energy applications. A set of sensors were installed to monitor the electric current and voltage of the energy generated, the energy stored and the energy used by the loads that may be connected to the system. Other parameters like solar radiations (both on the horizontal and on the photovoltaic generation planes) and temperatures (of both the environment and the photovoltaic module) were monitored. This was done while considering the important role of temperature in the photovoltaic module performance. Finally, a measurement and communication hardware was installed to interface the system developed with a conventional computer. In this way, the performance of the overall system in real rural conditions could be evaluated efficiently. Visual software that reads, visualizes and saves the data generated by the system was also developed by means of the LabVIEW programming environment

  13. 39 CFR 122.2 - Stand-alone special services.

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Stand-alone special services. 122.2 Section 122.2 Postal Service UNITED STATES POSTAL SERVICE POST OFFICE SERVICES [DOMESTIC MAIL] SERVICE STANDARDS FOR MARKET-DOMINANT SPECIAL SERVICES PRODUCTS § 122.2 Stand-alone special services. (a) The service standard...

  14. Hydrogen Gas Production in a Stand-Alone Wind Farm

    M. Naziry Kordkandy

    2017-04-01

    Full Text Available This paper is analyzing the operation of a stand-alone wind farm with variable speed turbines, permanent magnet synchronous generators (PMSG and a system for converting wind energy during wind speed variations. On this paper, the design and modeling of a wind system which uses PMSG’s to provide the required power of a hydrogen gas electrolyzer system, is discussed. This wind farm consists of three wind turbines, boost DC-DC converters, diode full bridge rectifiers, permanent magnet synchronous generators, MPPT control and a hydrogen gas electrolyzer system. The MPPT controller based on fuzzy logic is designed to adjust the duty ratio of the boost DC-DC converters to absorb maximum power. The proposed fuzzy logic controller assimilates, with (PSF MPPT algorithm which generally used to absorb maximum power from paralleled wind turbines and stores it in form of hydrogen gas. The system is modeled and its behavior is studied using the MATLAB software.

  15. Interpretation of erythrocyte histograms obtained from automated hematology analyzers in hematologic diseases

    Ali Maleki

    2015-12-01

    Full Text Available Background: Presently, the graphical data of blood cells (histograms and cytograms or/ scattergrams that they are usually available in all modern automated hematology analyzers are an integral a part of automated complete blood count (CBC. To find incorrect results from automated hematology analyzer and establish the samples that require additional analysis, Laboratory employees will use those data for quality control of obtaining results, to assist identification of complex and troublesome cases. Methods: During this descriptive analytic study, in addition to erythrocyte graphs from variety of patients, referring from March 2013 to Feb 2014 to our clinical laboratory, Zagros Hospital, Kermanshah, Iran, are given, the papers published in relevant literature as well as available published manuals of automatic blood cell counters were used. articles related to the key words of erythrocyte graphs and relevant literature as well as available published manuals of automatic blood cell counters were searched from valid databases such as Springer Link, google scholar, Pubmed and Sciencedirect. Then, the articles related to erythrogram, erythrocyte histogram and hematology analyzer graphs are involved in diagnosis of hematological disorder were searched and selected for this study. Results: Histograms and different automated CBC parameter become abnormal in various pathologic conditions, and can present important clues for diagnosis and treatment of hematologic and non-hematologic disorders. In several instances, these histograms have characteristic appearances in an exceedingly wide range of pathological conditions. In some hematologic disorders like iron deficiency or megaloblastic anemia, a sequential histogram can clearly show the progressive treatment and management. Conclusion: These graphical data are often accompanied by other automated CBC parameter and microscopic examination of peripheral blood smears (PBS, and can help in monitoring and

  16. Stand-alone induction generators for small water power schemes

    Harvey, Adam [Intermediate Technology Development Group, Rugby (United Kingdom); Smith, Nigel [Smith Associates, Nottingham (United Kingdom)

    1996-04-01

    Conventional technology for isolated power generation is the synchronous generator. Using stand-alone induction generators has proved to have tremendous advantages in remote regions of developing countries, where electricity has significant social benefits. (author)

  17. Basic Stand Alone Medicare DME Line Items PUF

    U.S. Department of Health & Human Services — This release contains the Basic Stand Alone (BSA) Durable Medical Equipment (DME) Line Items Public Use Files (PUF) with information from Medicare DME claims. The...

  18. Basic Stand Alone Skilled Nursing Facility Beneficiary PUF

    U.S. Department of Health & Human Services — This release contains the Basic Stand Alone (BSA) Skilled Nursing Facility (SNF) Beneficiary Public Use Files (PUF) with information from Medicare SNF claims. The...

  19. Evaluation of performance of veterinary in-clinic hematology analyzers.

    Rishniw, Mark; Pion, Paul D

    2016-12-01

    A previous study provided information regarding the quality of in-clinic veterinary biochemistry testing. However, no similar studies for in-clinic veterinary hematology testing have been conducted. The objective of this study was to assess the quality of hematology testing in veterinary in-clinic laboratories using results obtained from testing 3 levels of canine EDTA blood samples. Clinicians prepared blood samples to achieve measurand concentrations within, below, and above their RIs and evaluated the samples in triplicate using their in-clinic analyzers. Quality was assessed by comparison of calculated total error with quality requirements, determination of sigma metrics, use of a quality goal index, and agreement between in-clinic and reference laboratory instruments. Suitability for statistical quality control was determined using adaptations from the computerized program, EZRules3. Evaluation of 10 veterinary in-clinic hematology analyzers showed that these instruments often fail to meet quality requirements. At least 60% of analyzers reasonably determined RBC, WBC, HCT, and HGB, when assessed by most quality goal criteria; platelets were less reliably measured, with 80% deemed suitable for low platelet counts, but only 30% for high platelet counts, and automated differential leukocyte counts were generally considered unsuitable for clinical use with fewer than 40% of analyzers meeting the least stringent quality goal requirements. Fewer than 50% of analyzers were able to meet requirements for statistical quality control for any measurand. These findings reflect the current status of in-clinic hematology analyzer performance and provide a basis for future evaluations of the quality of veterinary laboratory testing. © 2016 American Society for Veterinary Clinical Pathology.

  20. Wavelength encoding technique for particle analyses in hematology analyzer

    Rongeat, Nelly; Brunel, Patrick; Gineys, Jean-Philippe; Cremien, Didier; Couderc, Vincent; Nérin, Philippe

    2011-07-01

    The aim of this study is to combine multiple excitation wavelengths in order to improve accuracy of fluorescence characterization of labeled cells. The experimental demonstration is realized with a hematology analyzer based on flow cytometry and a CW laser source emitting two visible wavelengths. A given optical encoding associated to each wavelength allows fluorescence identification coming from specific fluorochromes and avoiding the use of noisy compensation method.

  1. The stand-alone test and decreasing serial cost sharing

    Hougaard, Jens Leth; Thorlund-Petersen, Lars

    2000-01-01

    The rule of decreasing serial cost sharing defined in de Frutos [1] over the class of concave cost functions may violate the important stand-alone test. Sufficient conditions for the test to be satisfied are given, in terms of individual rationality as well as coalitional stability...

  2. Stand-alone solutions, computer networks and extern communications

    Tarschisch, H.

    1988-01-01

    The advantages of local networks over stand-alone solutions are presented. Of the local networks (LAN), two are presently at the center of attention: the bus and the ring. ETHERNET and the IBM-Token-Ring are described as typical examples. Access to public networks, especially TELEPAC and ISDN, is discussed. 12 figs

  3. Ampere hour method of sizing a stand alone photovoltaic system ...

    Stand-alone photovoltaic power systems are natural options for application in electrification of remote areas which are not served by the grid electricity supply system. An ampere-hour ... Sizing of the balance-of-system were carefully handled to avoid undersizing or oversizing and subsequent variation in supply reliability.

  4. Performance evaluation of Samsung LABGEO(HC10) Hematology Analyzer.

    Park, Il Joong; Ahn, Sunhyun; Kim, Young In; Kang, Seon Joo; Cho, Sung Ran

    2014-08-01

    The Samsung LABGEO(HC10) Hematology Analyzer (LABGEO(HC10)) is a recently developed automated hematology analyzer that uses impedance technologies. The analyzer provides 18 parameters including 3-part differential at a maximum rate of 80 samples per hour. To evaluate the performance of the LABGEO(HC10). We evaluated precision, linearity, carryover, and relationship for complete blood cell count parameters between the LABGEO(HC10) and the LH780 (Beckman Coulter Inc) in a university hospital in Korea according to the Clinical and Laboratory Standards Institute guidelines. Sample stability and differences due to the anticoagulant used (K₂EDTA versus K₃EDTA) were also evaluated. The LABGEO(HC10) showed linearity over a wide range and minimal carryover ( 0.92) except for mean corpuscular hemoglobin concentration. The bias estimated was acceptable for all parameters investigated except for monocyte count. Most parameters were stable until 24 hours both at room temperature and at 4°C. The difference by anticoagulant type was statistically insignificant for all parameters except for a few red cell parameters. The accurate results achievable and simplicity of operation make the unit recommendable for small to medium-sized laboratories.

  5. Models for a stand-alone PV system

    Hansen, A.D.; Sørensen, Poul Ejnar; Hansen, L.H.

    2001-01-01

    are based on the model descriptions found in the literature. The battery model is developed at UMASS and is known as the Kinetic Battery Model(KiBaM). The other component models in the PV system are based on simple electrical knowledge. The implementation is done using Matlab/Simulink, a simulation program......This report presents a number of models for modelling and simulation of a stand-alone photovoltaic (PV) system with a battery bank verified against a system installed at Risø National Laboratory. The work has been supported by the Danish Ministry ofEnergy, as a part of the activities in the Solar...... Energy Centre Denmark. The study is carried out at Risø National Laboratory with the main purpose to establish a library of simple mathematical models for each individual element of a stand-alone PVsystem, namely solar cells, battery, controller, inverter and load. The models for PV module and battery...

  6. Optimal sizing method for stand-alone photovoltaic power systems

    Groumpos, P P; Papageorgiou, G

    1987-01-01

    The total life-cycle cost of stand-alone photovoltaic (SAPV) power systems is mathematically formulated. A new optimal sizing algorithm for the solar array and battery capacity is developed. The optimum value of a balancing parameter, M, for the optimal sizing of SAPV system components is derived. The proposed optimal sizing algorithm is used in an illustrative example, where a more economical life-cycle cost has bene obtained. The question of cost versus reliability is briefly discussed.

  7. Models for a stand-alone PV system[Photovoltaic

    Hansen, A.D.; Soerensen, P.; Hansen, L.H.; Bindner, H.

    2000-12-01

    This report presents a number of models for modelling and simulation of a stand-alone photovoltaic (PV) system with a battery bank verified against a system installed at Risoe National Laboratory. The work has been supported by the Danish Ministry of Energy, as a part of the activities in the Solar Energy Centre Denmark. The study is carried out at Risoe National Laboratory with the main purpose to establish a library of simple mathematical models for each individual element of a stand-alone PV system, namely solar cells, battery, controller, inverter and load. The models for PV module and battery are based on the model descriptions found in the literature. The battery model is developed at UMASS and is known as the Kinetic Battery Model (KiBaM). The other component models in the PV system are based on simple electrical knowledge. The implementation is done using Matlab/Simulink, a simulation program that provides a graphical interface for building models as modular block diagrams. The non-linear behaviour of the battery, observed in the measurements, is investigated and compared to the KiBaM model's performance. A set of linear Black box models are estimated based on the battery measurements. The performance of the best linear Black box model is compared to the KiBaM model. A validation of each of the implemented mathematical model is performed by an interactive analysis and comparison between simulation results and measurements, acquired from the stand-alone PV system at Risoe. (au)

  8. Size-Prediction Analysis for Stand-Alone Photovoltaic System

    Erusiafe, N. E.; Chendo, M. A. C.

    2002-01-01

    The cost - effectiveness of photovoltaic (PV) generator depends, among others, on its ability to satisfy energy demand and the cost of achieving this. In this work a step - by - step procedure for predicting the size of the main components of a stand - alone PV system (array and storage) is presented. The results yield an expression which can he used lo determine the size of both components at optimum cost and desired reliability. The result from this work compare favourably with some earlier works in that, the system sizes shows some degree of agreement

  9. Availability model of stand-alone photovoltaic system

    Mazurek, G.

    2017-08-01

    In this paper we present a simple, empirical model of stand-alone photovoltaic power system availability. The model is a final result of five-year long studies and ground measurements of solar irradiation carried out in Central Europe. The obtained results facilitate sizing of PV modules that have to be installed with taking into account system's availability level in each month of a year. The model can be extended to different geographical locations, with help of local meteorological data or solar irradiation datasets derived from satellite measurements.

  10. Future UK markets for stand-alone renewable energy systems

    Paish, O.

    1999-01-01

    A study to identify and quantify the market for stand-alone renewable energy supplies of power (photovoltaics, wind and micro-hydro electricity systems) was described. The study focused on small systems, generally less than a few kW installed capacity. It was suggested that in the UK, the emphasis on grid-connected renewable energy technologies (RETs) has blurred the fact that it is 'off-grid' renewable systems that can offer more immediate real commercial markets for the renewables business. With the likelihood of a significant increase in demand for renewables world wide over the next ten years, the UK needs to make a special effort to become involved

  11. Benchmarking the Collocation Stand-Alone Library and Toolkit (CSALT)

    Hughes, Steven; Knittel, Jeremy; Shoan, Wendy; Kim, Youngkwang; Conway, Claire; Conway, Darrel J.

    2017-01-01

    This paper describes the processes and results of Verification and Validation (VV) efforts for the Collocation Stand Alone Library and Toolkit (CSALT). We describe the test program and environments, the tools used for independent test data, and comparison results. The VV effort employs classical problems with known analytic solutions, solutions from other available software tools, and comparisons to benchmarking data available in the public literature. Presenting all test results are beyond the scope of a single paper. Here we present high-level test results for a broad range of problems, and detailed comparisons for selected problems.

  12. Enhanced current and voltage regulators for stand-alone applications

    Federico, de Bosio; Pastorelli, Michele; Antonio DeSouza Ribeiro, Luiz

    2016-01-01

    State feedback decoupling permits to achieve a better dynamic response for Voltage Source in stand-alone applications. The design of current and voltage regulators is performed in the discrete-time domain since it provides better accuracy and allows direct pole placement. As the attainable...... bandwidth of the current loop is mainly limited by computational and PWM delays, a lead compensator structure is proposed to overcome this limitation. The design of the voltage regulator is based on the Nyquist criterion, verifying to guarantee a high sensitivity peak. Discrete-time domain implementation...

  13. Stand-Alone Ethics, Social Responsibility, and Sustainability Course Requirements: A Snapshot from Australia and New Zealand

    Rundle-Thiele, Sharyn R.; Wymer, Walter

    2010-01-01

    This article analyzes the extent to which Australian and New Zealand marketing educators use dedicated or stand-alone courses to equip students with alternative views of business. A census of marketing programs in degree-granting universities was conducted. Program brochures were obtained via the Internet and were content analyzed. This study…

  14. Magnetic field measurements near stand-alone transformer stations.

    Kandel, Shaiela; Hareuveny, Ronen; Yitzhak, Nir-Mordechay; Ruppin, Raphael

    2013-12-01

    Extremely low-frequency (ELF) magnetic field (MF) measurements around and above three stand-alone 22/0.4-kV transformer stations have been performed. The low-voltage (LV) cables between the transformer and the LV switchgear were found to be the major source of strong ELF MFs of limited spatial extent. The strong fields measured above the transformer stations support the assessment method, to be used in future epidemiological studies, of classifying apartments located right above the transformer stations as highly exposed to MFs. The results of the MF measurements above the ground around the transformer stations provide a basis for the assessment of the option of implementing precautionary procedures.

  15. Integral type small PWR with stand-alone safety

    Makihara, Yoshiaki

    2001-01-01

    A feasibility study is achieved on an integral type small PWR with stand-alone safety. It is designed to have the following features. (1) The coolant does not leak out at any accidental condition. (2) The fuel failure does never occur while it is supposed on the large scale PWR at the design base accident. (3) At any accidental condition the safety is secured without any support from the outside (stand-alone safety secure). (4) It has self-regulating characteristics and easy controllability. The above features can be satisfied by integrate the steam generator and CRDM in the reactor vessel while the pipe line break has to be considered on the conventional PWR. Several counter measures are planned to satisfy the above features. The economy feature is also attained by several simplifications such as (1) elimination of main coolant piping and pressurizer by the integration of primary cooling system and self-pressurizing, (2) elimination of RCP by application of natural circulating system, (3) elimination of ECCS and accumulator by application of static safety system, (4) large scale volume reduction of the container vessel by application of integrated primary cooling system, (5) elimination of boric acid treatment by deletion of chemical shim. The long operation period such as 10 years can be attained by the application of Gd fuel in one batch refueling. The construction period can be shortened by the standardizing the design and the introduction of modular component system. Furthermore the applicability of the reduced modulation core is also considered. (K. Tsuchihashi)

  16. Design and Operation Studies of A Stand-Alone PV Generation System

    Hu, Yanting; Chen, Zhe; Zhang, Donglai

    2013-01-01

    This paper discusses the modeling, design and operation of a PV powered stand-alone system, which includes a PV array, a battery bank, power electronic converters and the associated control system. The design considerations are analyzed and a design platform is presented. Furthermore the operation...... modes of the system are described. A power electronic system with the associated control scheme has been proposed and simulation models have been developed. Simulation studies have been conducted on an example system; the results have demonstrated the effectiveness of the presented methods....

  17. A control strategy for PV stand-alone applications

    Slouma, S.; Baccar, H.

    2015-04-01

    This paper proposes a stand-alone photovoltaic (PV) system study in domestic applications. Because of the decrease in power of photovoltaic module as a consequence of changes in solar radiation and temperature which affect the photovoltaic module performance, the design and control of DC-DC buck converter was proposed for providing power to the load from a photovoltaic source.In fact, the control of this converter is carried out with integrated MPPT (Maximum Power Point Tracking) algorithm which ensures a maximum energy generated by the PV arrays. Moreover, the output stage is composed by a battery energy storage system, dc-ac inverter, LCL filter which enables higher efficiency, low distortion ac waveforms and low leakage currents. The control strategy adopted is cascade control composed by two regulation loops.Simulations performed with PSIM software were able to validate the control system.The realization and testing of the photovoltaic system were achieved in the Photovoltaic laboratory of the Centre for Research and Energy Technologies at the Technopark Borj Cedria. Experimental results verify the effeciency of the proposed system.

  18. A control strategy for PV stand-alone applications

    Slouma, S; Baccar, H

    2015-01-01

    This paper proposes a stand-alone photovoltaic (PV) system study in domestic applications. Because of the decrease in power of photovoltaic module as a consequence of changes in solar radiation and temperature which affect the photovoltaic module performance, the design and control of DC-DC buck converter was proposed for providing power to the load from a photovoltaic source.In fact, the control of this converter is carried out with integrated MPPT (Maximum Power Point Tracking) algorithm which ensures a maximum energy generated by the PV arrays. Moreover, the output stage is composed by a battery energy storage system, dc-ac inverter, LCL filter which enables higher efficiency, low distortion ac waveforms and low leakage currents. The control strategy adopted is cascade control composed by two regulation loops.Simulations performed with PSIM software were able to validate the control system.The realization and testing of the photovoltaic system were achieved in the Photovoltaic laboratory of the Centre for Research and Energy Technologies at the Technopark Borj Cedria. Experimental results verify the effeciency of the proposed system

  19. Improving efficiency of a regional stand alone bone bank.

    Warnock, Jonathan M; Rowan, Clare H; Davidson, Helen; Millar, Ciara; McAlinden, M Gavan

    2016-03-01

    The introduction of a stand-alone Bone Bank in our Regional Orthopaedic Hospital has improved the availability of femoral head allograft. Benninger et al. (Bone Joint J 96-B:1307-1311, 2014), demonstrated their institutions bank to be cost effective despite a 30 % discard rate for harvested allograft. We sought to audit our own discard rates and subsequent cost-effectiveness of our bone bank. Donor recruitment. Before approaching a potential donor, our establishment's nurse specialists review their clinical notes and biochemical laboratory results, available on a regional Electronic Care Records. They view femoral head architecture on radiographs against set criteria, Patient Archive and Communication system (SECTRA, Sweden). In total 1383 femoral heads were harvested, 247 were discarded giving an overall rate of 17.9 %. The most common reasons for discard of harvested graft was a positive microbiology/bacteriology result, n = 96 (38.9 %). After a rise in discard rates in 2007, we have steadily reduced our discard rates since 2006/2007 (28.2 %), 2008/2009 (17 %), 2010/2011 (14.8 %), and finally to 10.3 % in 2012/2013. In the current financial year, our cost to harvest, test, store and release a femoral head is £ 610. With a structured donor recruitment process and unique pre-operative radiographic analysis we have successfully reduced our discard rates bi-annually making our bone bank increasingly cost-effective.

  20. The Stand-alone Heliostat; El Heliostato Autonomo

    Garcia Navajas, G.; Egea Gea, A. [Ciemat. Madrid (Spain)

    2000-07-01

    The first Autonomous Heliostat has been developed by CIEMAT at PSA facilities in Almeria. This heliostat is an innovative approach to reducing the civil engineering work costs in heliostat fields of central tower plants. Channels, cables and other electric elements have been eliminated in the new heliostat. Thus, one 70-m''2, classical T glass/metal heliostat has been adapted to include all the new stand-alone concept components. A PV system is able to drive two sun-tracking DC motors between 5 and 24 Vdc, 0 and 15A. The heliostat communicates with the control room 400-m away by using a radio-modern working at 9600 baud. An anemometer, a wind switcher, light and ambient temperature sensors have been installed on the heliostat for self-protection decision-making. A PV panel integrated into the heliostat reflecting surface, eliminates cabling and other elements required for a conventional power supply. Communication lines between master control and local control have been replaced by radio-modern. Testing has validated the technical feasibility of the prototype and quantified the real consumption and efficiencies of new elements. The extra costs produced by the autonomous concepts are compared with the cost of civil work in conventional heliostat field. (Author) 8 refs.

  1. The Stand-alone Heliostat; El Heliostato Autonomo

    Garcia Navajas, G; Egea Gea, A [Ciemat. Madrid (Spain)

    2000-07-01

    The first Autonomous Heliostat has been developed by CIEMAT at PSA facilities in Almeria. This heliostat is an innovative approach to reducing the civil engineering work costs in heliostat fields of central tower plants. Channels, cables and other electric elements have been eliminated in the new heliostat. Thus, one 70-m''2, classical T glass/metal heliostat has been adapted to include all the new stand-alone concept components. A PV system is able to drive two sun-tracking DC motors between 5 and 24 Vdc, 0 and 15A. The heliostat communicates with the control room 400-m away by using a radio-modern working at 9600 baud. An anemometer, a wind switcher, light and ambient temperature sensors have been installed on the heliostat for self-protection decision-making. A PV panel integrated into the heliostat reflecting surface, eliminates cabling and other elements required for a conventional power supply. Communication lines between master control and local control have been replaced by radio-modern. Testing has validated the technical feasibility of the prototype and quantified the real consumption and efficiencies of new elements. The extra costs produced by the autonomous concepts are compared with the cost of civil work in conventional heliostat field. (Author) 8 refs.

  2. Feasibility and Optimal Design of a Stand-Alone Photovoltaic Energy System for the Orphanage

    Vincent Anayochukwu Ani

    2014-01-01

    Full Text Available Access to electricity can have a positive psychological impact through a lessening of the sense of exclusion, and vulnerability often felt by the orphanages. This paper presented the simulation and optimization study of a stand-alone photovoltaic power system that produced the desired power needs of an orphanage. Solar resources for the design of the system were obtained from the National Aeronautics and Space Administration (NASA Surface Meteorology and Solar Energy website at a location of 6°51′N latitude and 7°35′E longitude, with annual average solar radiation of 4.92 kWh/m2/d. This study is based on modeling, simulation, and optimization of energy system in the orphanage. The patterns of load consumption within the orphanage were studied and suitably modeled for optimization. Hybrid Optimization Model for Electric Renewables (HOMER software was used to analyze and design the proposed stand-alone photovoltaic power system model. The model was designed to provide an optimal system configuration based on an hour-by-hour data for energy availability and demands. A detailed design, description, and expected performance of the system were presented in this paper.

  3. R and D into stand-alone PV systems for export

    NONE

    1996-09-01

    The current status of photovoltaic (PV) technology is reviewed for systems to provide electricity where mains supplies are unavailable, known as stand-alone PV systems. Typical applications and experiences with installed stand-alone systems are described. Economic issues and barriers to the wide use of PV systems are also examined. (UK)

  4. An Analysis of Stand-alone GPS Quality and Simulated GNSS Quality for Road Pricing

    Zabic, Martina; Nielsen, Otto Anker

    2006-01-01

    Use of GPS for road pricing has often been suggested as the way of creating more efficient charging strategies than existing systems based on cordon lines or time use. In Denmark, Copenhagen participated with the AKTA project in the PRoGRESS programme, sponsored by the EU. The major part...... of the AKTA project was to equip 500 cars with GPS receivers. The paper presents the methods and results from a study of GPS quality in relation to road pricing in a dense urban area. The collected data from 500 cars over a two-year period in the Copenhagen region was analyzed in order to determine whether...... the stand alone GPS quality and reliability is adequate for implementation of an operational road pricing system in Copenhagen. The results from the analysis show that the satellite availability in Copenhagen is not sufficient to form the basis for a reliable operational road pricing system. The narrow...

  5. Study of Stand-Alone Microgrid under Condition of Faults on Distribution Line

    Malla, S. G.; Bhende, C. N.

    2014-10-01

    The behavior of stand-alone microgrid is analyzed under the condition of faults on distribution feeders. During fault since battery is not able to maintain dc-link voltage within limit, the resistive dump load control is presented to do so. An inverter control is proposed to maintain balanced voltages at PCC under the unbalanced load condition and to reduce voltage unbalance factor (VUF) at load points. The proposed inverter control also has facility to protect itself from high fault current. Existing maximum power point tracker (MPPT) algorithm is modified to limit the speed of generator during fault. Extensive simulation results using MATLAB/SIMULINK established that the performance of the controllers is quite satisfactory under different fault conditions as well as unbalanced load conditions.

  6. Energy management system for stand-alone diesel-wind-biomass microgrid with energy storage system

    Wang, Chengshan; Liu, Yixin; Li, Xialin; Guo, Li; Qiao, Lei; Lu, Hai

    2016-01-01

    An energy management system for stand-alone microgrid composed of diesel generators, wind turbine generator, biomass generator and an ESS (energy storage system) is proposed in this paper. Different operation objectives are achieved by a hierarchical control structure with different time scales. Firstly, the optimal schedules of the diesel generators, wind turbine generator, biomass generator and ESS are determined fifteen minutes ahead according to the super short-term forecast of load and wind speed in the optimal scheduling layer. Comprehensive analysis which takes the uncertainty of load and wind speed into account is conducted in this layer to minimize the operation cost of the system and ensure a desirable range of the state of charge of the ESS. Secondly, the operation points of each unit are regulated dynamically to guarantee real-time power balance and safety range of diesel generation in the real-time control layer, based on which the response capability when suffering significant forecast deviation and other emergency issues, e.g. sudden load-up can be improved. Finally, the effectiveness of the proposed energy management strategy is verified on an RT-Lab based real-time simulation platform, and the economic performances with different types of ESS are analyzed as well. - Highlights: • A hierarchical control strategy is proposed for a stand-alone microgrid. • The uncertainties of load and wind speed have been considered. • Better economic performance and high reliability of the system can be achieved. • The influences of different energy storage systems have been analyzed.

  7. Hematology

    Konrad, H.

    1976-01-01

    The latest state of nuclear medical functional diagnostics in hematology is reviewed. In addition to methods for determining the blood volume, iron kinetics, the survival time of erythrocytes as well as resorption and serum levels of vitamin B 12 kinetic investigations of thrombocytes, granulocytes, lymphocytes, and the spleen with the aid of radioisotopes are described in detail. Also included are tables with data about radiation doses to patients due to medical application of radioisotopes as well as a compilation of physical properties of radioisotopes which are used in hematological diagnosis such as 59 Fe, 51 Cr, 131 I, 125 I, 58 Co, 57 Co, 32 P, 3 H, sup(99m)Tc, 113 In. Finally, radiopharmaceuticals for hematological diagnostics are listed, which are commercially available in the German Democratic Republic. The booklet is intended for physicians working in outpatient departments and hospitals

  8. Clinical outcome of stand-alone ALIF compared to posterior instrumentation for degenerative disc disease

    Udby, Peter M.; Bech-Azeddine, Rachid

    2015-01-01

    The objective of the article was to: a) present results from a case cohort pilot study comparing stand-alone ALIF and TLIF and, b) review the literature on studies comparing the clinical outcome of stand-alone ALIF with posterior instrumentation including TLIF or PLIF, in patients with disabling...... low back pain resulting from degenerative disc disease. ALIF surgery has previously been linked with certain high risk complications and unfavorable long term fusion results. Newer studies suggest that stand-alone ALIF can possibly be advantageous compared to other types of posterior instrumented...

  9. A Case Study of Control and Improved Simplified Swarm Optimization for Economic Dispatch of a Stand-Alone Modular Microgrid

    Xianyong Zhang

    2018-03-01

    Full Text Available Due to the complex configuration and control framework, the conventional microgrid is not cost-effective for engineering applications with small or medium capacity. A stand-alone modular microgrid with separated AC bus and decentralized control strategy is proposed in this paper. Each module is a self-powered system, which consists of wind and solar power, a storage battery, load and three-port converter. The modules are interconnected by three-port converters to form the microgrid. Characteristics, operation principle, control of the modular microgrid and the three-port converter are analyzed in detail. Distributed storage batteries enable power exchanges among modules to enhance economic returns. Economic dispatch of the stand-alone modular microgrid is a mixed-integer programming problem. A day-ahead operation optimization model including fuel cost, battery operation cost, and power transmission cost is established. Because there are so many constraints, it is difficult to produce a feasible solution and even more difficult to have an improved solution. An improved simplified swarm optimization (iSSO method is therefore proposed. The iSSO scheme designs the new update mechanism and survival of the fittest policy. The experimental results from the demonstration project on DongAo Island reflect the effectiveness of the stand-alone modular microgrid and the economic dispatch strategy based on the iSSO method.

  10. Hematology

    Price, D.C.; Ries, C.

    1975-01-01

    This paper reviews the wide variety of radioisotopic techniques available to pediatricians in hematologic evaluation of their patients, with comments on the tracer techniques, and an indication of some new territory in splenic evaluation and nonradioactive tracers which may prove to be of considerable interest in the future. The only differences in applying these techniques to the pediatric population, compared with the adult population, lie in the different spectrum of hematologic diseases under consideration in this age group and the greater sensitivity to problems of radiation exposure which the pediatrician and the nuclear medicine physician must have in administering the isotopes in vivo. With these considerations in mind, the usefulness of such radioisotopic techniques in the evaluation of pediatric hematologic disease remains unquestionable. Radiopharmaceuticals and the radiation doses associated with the various procedures are listed. It is hoped in the future that fluorescent excitation techniques will replace at least s []me of the radioisotope techniques, obviating all considerations of patient irradiation in such instances. (auth)

  11. Procedures for Determining the Performance of Stand-Alone Photovoltaic Systems; TOPICAL

    DeBlasio, R.; Durand, S.; Hansen, R.; Hutchinson, P.; Kroposki, B.; McNutt, P.; Rosenthal, A.; Thomas, M.

    1999-01-01

    This document provides the procedures for determining the performance of stand-alone PV systems. The procedures in this document provide a common approach for evaluating whether a given PV system is suitable to perform the function for which it was designed and manufactured to accomplish, and whether it will provide adequate power to run the load. These procedures cover small stand-alone PV systems. They cover complete outdoor system testing. Test results are valid only for the system that is tested

  12. Comparative analysis of distributed MPPT controllers for partially shaded stand alone photovoltaic systems

    Muthuramalingam, M.; Manoharan, P.S.

    2014-01-01

    Highlights: • Analyzes the performance of ANN and ANFIS MPPT algorithms by stand alone PV system. • ISSBC with ANFIS can provide the overall efficiency higher than ANN. • CHBMLI integrate with SHE ANN modulation technique improve output voltage quality. • Simulation and hardware results show the ANFIS algorithm efficient than ANN algorithm. - Abstract: This paper presents a unique combination of an interleaved soft switched boost converter (ISSBC) run by a set of two photovoltaic panel (PV) with a distributed MPPT, suitable to guarantee MPPT even under partial shadowed conditions, managed by an adaptive neuro fuzzy inference system trained by the training data derived from a particle swarm optimization (PSO–ANFIS) unit. The ISSBC is followed by a, single phase cascaded H bridge five-level inverter (CHI) driven by the individual DC outputs of the ISSBC, with selective harmonic elimination scheme to eliminate typically the seventh order harmonics. A comparison of different intelligent distributed maximum power point tracking (MPPT) algorithms for photovoltaic (PV) system under partial shadow conditions is carried out. The use of the ISSBC guarantees mitigation of ripple and it is meant to handle higher currents with minimal switching losses. Simulation was carried out in the Matlab Simulink environment and an experimental verification with a scaled down model validated the proposed scheme. It has been thus established, by both simulation and experimental verification, that the PSO–ANFIS model of distributed MPPT scheme of control outperforms other schemes of control for MPPT

  13. Stand-alone photovoltaic systems in the Netherlands. Evaluation of the market introduction

    Cloin, J.; Van Dijk, A.L.; Westra, C.A.

    1999-08-01

    The policy followed for stand-alone PV systems in the Netherlands is evaluated for the period 1997-1998. The world-wide powerful growth of the PV industry is not being followed by the increase in volume of implemented stand-alone PV systems in the Netherlands. This leads to the question whether the Dutch policy to stimulate stand-alone PV systems is effective. Recommendations on the use of communication as a strategic instrument are given, including the drawing up of a marketing plan. Other recommendations include increased transparency in the application for subsidies and a pro-active role of the Netherlands Agency for Energy and the Environment (Novem) in the contact with relevant market parties. The increased focus on product development aimed at the environmental benefits and general reliability of PV systems is recommended. 38 refs

  14. Stand-alone wind system with Vanadium Redox Battery energy storage

    Teodorescu, Remus; Barote, L.; Weissbach, R.

    2008-01-01

    Energy storage devices are required for power balance and power quality in stand alone wind energy systems. A Vanadium Redox Flow Battery (VRB) system has many features which make its integration with a stand-alone wind energy system attractive. This paper proposes the integration of a VRB system...... with a typical stand-alone wind energy system during wind speed variation as well as transient performance under variable load. The investigated system consists of a variable speed wind turbine with permanent magnet synchronous generator (PMSG), diode rectifier bridge, buck-boost converter, bidirectional charge...... controller, transformer, inverter, ac loads and VRB (to store a surplus of wind energy and to supply power during a wind power shortage). The main purpose is to supply domestic appliances through a single phase 230V, 50Hz inverter. Simulations are accomplished in order to validate the stability of the supply....

  15. Connecting embedded and stand-alone peer mentoring models to enhance student engagement

    Rhys Cooper

    2018-03-01

    Full Text Available This paper outlines the Trident Student Mentoring Program that runs in the College of Engineering at Victoria University, Melbourne, Australia. The program offers both embedded and stand-alone models of peer mentoring services to the same cohort of first-year students. It shows that by forming strong links between these two types of peer mentoring models, the inherent challenges of both, such as low attendance rates in stand-alone models and short periods of peer to peer time in embedded models, are mitigated.

  16. Sensorless direct voltage control of the stand-alone brushless doubly-fed generator

    Liu, Yi; Xu, Wei; Xiong, Fei

    2017-01-01

    The conventional stand-alone brushless doubly-fed generator (BDFG) control strategies need the feedback from the rotor position or speed sensors, which can reduce system reliability and increase the cost and axial volume of the machine. In this paper, a sensorless direct voltage control (DVC) str......) strategy is presented for the stand-alone BDFG. The satisfactory dynamic performance is verified by experimental results under four kinds of typical operation conditions. Besides, the proposed control strategy is robust due to no generator parameters being required....

  17. Linguistic and Structural Analyses of Stand-Alone Literature Reviews: Seventy-Five Years of Change

    Wright, Heidi Rachel

    2016-01-01

    The purpose of this dissertation is to offer a multifaceted overview of stand-alone literature reviews. These texts, literature reviews published unattached to research articles, have existed for centuries but remained largely unstudied by linguists. Thus, the goal of this project is to present these reviews' situational, grammatical, and…

  18. Assessment of Stand-Alone Displays for Time Management in a Creativity-Driven Learning Environment

    Frimodt-Møller, Søren

    2017-01-01

    This paper considers the pros and cons of stand-alone displays, analog (e.g. billboards, blackboards, whiteboards, large pieces of paper etc.) as well as digital (e.g. large shared screens, digital whiteboards or similar), as tools for time management processes in a creativity-driven learning...

  19. Stand-alone version of the 11kW Gaia wind turbine

    Bindner, H.; Rosas, P.A.C.; Teodorescu, R.

    2004-01-01

    This report describes the development of a stand-alone version of the 11kW Gaia wind turbine. Various possible configurations are investigated and a configuration using a back-to-back converter is chosen. A model is developed for controller design of thefast controllers of the unit. Controllers...... assessment and controller design a dynamic performance assessment model has been developed....

  20. A maximum power point tracking scheme for a 1kw stand-alone ...

    A maximum power point tracking scheme for a 1kw stand-alone solar energy based power supply. ... Nigerian Journal of Technology ... A method for efficiently maximizing the output power of a solar panel supplying a load or battery bus under ...

  1. Use of Super-Capacitor to Enhance Charging Performance of Stand-Alone Solar PV System

    Huang, B. J.; Hsu, P. C.; Ho, P. Y

    2011-01-01

    Introduction: The battery charging performance in a stand-alone solar PV system affects the PV system efficiency and the load operating time. The New Energy Center of National Taiwan University has been devoted to the development of a PWM charging

  2. Environmental/Climatic Effect on Stand-Alone Solar Energy Supply ...

    This paper investigates the climatic eects and environmental variations on the performance of a stand-alone photovoltaic system. The eects of partial shading with dierent climate conditions and load resistance variations were examined. A survey of some of the work done in this eld of environmental eect on solar panel was ...

  3. 11kW stand alone wind turbine based on proven wind turbine

    Bindner, H.; Wodstrup, J.; Andersen, J.

    2004-01-01

    and enable control of frequency and voltage independently on both the grid side and the generator side. The prototype has been installed at Risø. The paper will present results from test runs of the system both operating stand-alone supplying a single load and in parallel operation with a diesel genset....

  4. Modelling of fluid-solid interaction using two stand-alone codes

    Grobler, Jan H

    2010-01-01

    Full Text Available A method is proposed for the modelling of fluid-solid interaction in applications where fluid forces dominate. Data are transferred between two stand-alone codes: a dedicated computational fluid dynamics (CFD) code capable of free surface modelling...

  5. ISO/IEC 17025 Sysmex R-500 hematology reticulocyte analyzer validation.

    Dimopoulou, H A; Theodoridis, T; Galea, V; Christopoulou-Cokkinou, V; Spyridaki, M-H E; Georgakopoulos, C G

    2007-01-01

    The Sysmex R-500 (R-500) Hematology Analyzer is a bench-top system appropriate for the analysis of limited batches of blood samples. The R-500 provides percentage proportional (RET%), absolute reticulocyte (RET#), and absolute red blood cell (RBC#) counts. The system was validated at the Doping Control Laboratory of Athens, according to the International Committee for Standardization in Hematology, International Standards Organization (ISO/IEC) 17025, and World Antidoping Agency (WADA) specifications. The instrument calibration was performed according to the manufacturer and validation parameters comprised linearity, precision, uncertainty (intermediate and long-term precision), comparability, effect of drift, carryover, stability, and accuracy. The linearity and the comparability studies for RET#, RET%, and RBC# were expressed in regression factors (R2) and coefficients of correlation [r(x, y)], respectively. For the precision studies, the coefficients of variation for RET#, RET%, and RBC# were 9.49%, 9.83%, and ISO/IEC 17025 and WADA specifications.

  6. Performance evaluation of the Sysmex® XE-2100D automated hematology analyzer

    Tavany Elisa Santos Maciel

    2014-02-01

    Full Text Available Introduction: The Sysmex® XE-2100D is a multiparameter hematology analyzer designed for hematology testing in samples with ethylenediamine tetraacetic acid (EDTA. Objectives: Considering the importance of this hematology analyzer for clinical and laboratory practice, the objective of this study was to evaluate its analytical performance, comparing the obtained results with quality specifications described in literature. Material and method: In the evaluation of analytical performance, according to recommendations of the document H26-A2 of the Clinical and Laboratory Standards Institute (CLSI, intra-run imprecision, inter-run imprecision, linearity, carryover, autosampler evaluation, clinical sensitivity of the atypical lymphocytes flag (n = 400 samples were included, as well as the comparison between automated and manual leukocyte differential count (n = 400 samples, based on an adaptation of the document H20-A2 of CLSI. Results: Repeatability, reproducibility, linearity and carryover were satisfactory according to the manufacturer's specifications. The clinical sensitivity of the atypical lymphocytes flag showed efficiency, sensitivity and specificity of 92.5%, 65.2% and 94.1% respectively. The correlation coefficients between the automated and manual differential counts of neutrophils, lymphocytes, monocytes, eosinophils and basophils were 0.991, 0.99, 0.872, 0.974 and 0.557, respectively. Conclusions: The results were in accordance with quality specifications described in literature, indicating reliability in Sysmex® XE-2100D. This fact ensures certainty to both laboratory professionals and medical staff. We conclude that the Sysmex® XE-2100D showed excellent analytical performance, and is useful to provide reliable hematology data.

  7. Optimum capacity determination of stand-alone hybrid generation system considering cost and reliability

    Chen, Hung-Cheng

    2013-01-01

    Highlights: ► This paper presents a methodology for the installation capacity optimization. ► Hybrid generation system is optimized by application of adaptive genetic algorithm. ► A cost investigation is made under various conditions and component characteristics. ► The optimization scheme is validated to meet the annual power load demand. -- Abstract: The aim of this work is to present an optimization methodology for the installation capacity of a stand-alone hybrid generation system, taking into consideration the cost and reliability. Firstly, on the basis of derived steady state models of a wind generator (WG), a photovoltaic array (PV), a battery and an inverter, the hybrid generation system is modeled for the purpose of capacity optimization. Secondly, the power system is analyzed for determining both the system structure and the operation control strategy. Thirdly, according to hourly weather database of wind speed, temperature and solar irradiation, annual power generation capacity is estimated for the system match design in order that an annual power load demand can be met. The capacity determination of a hybrid generation system becomes complicated as a result of the uncertainty in the renewable energy together with load demand and the nonlinearity of system components. Aimed at the power system reliability and the cost minimization, the capacity of a hybrid generation system is optimized by application of an adaptive genetic algorithm (AGA) to individual power generation units. A total cost investigation is made under various conditions, such as wind generator power curves, battery discharge depth and the loss of load probability (LOLP). At the end of this work, the capacity of a hybrid generation system is optimized at two installation sites, namely the offshore Orchid Island and Wuchi in Taiwan. The optimization scheme is validated to optimize power capacities of a photovoltaic array, a battery and a wind turbine generator with a relative

  8. Feasibility study and energy conversion analysis of stand-alone hybrid renewable energy system

    Baghdadi, Fazia; Mohammedi, Kamal; Diaf, Said; Behar, Omar

    2015-01-01

    Highlights: • Hybrid stand-alone wind–solar–fossil power system is analyzed. • Measurement data are used to evaluate system performance. • The proposed system can generate about 70% from renewables. • Such a hybrid plant is very promising for remote regions in Algeria. - Abstract: There is a great interest in the development of renewable power technologies in Algeria, and more particularly hybrid concept. The present paper has investigated the performance of hybrid PV–Wind–Diesel–Battery configuration based on hourly measurements of Adrar climate (southern Algeria). Data of global solar radiation, ambient temperature and wind speed for a period of one year have been used. Firstly, the proposed hybrid system has been optimized by means of HOMER software. The optimization process has been carried out taking into account renewable resources potential and energy demand; while maximizing renewable electricity use and fuel saving are the purpose. In the second step, a mathematical model has been developed to ensure efficient energy management on the basis of various operation strategies. The analysis has shown that renewable energy system (PV–Wind) is able to supply about 70% of the demand. Wind power has ranked first with 43% of the annual total electricity production followed by diesel generator (with 31%) while the remaining fraction is being to PV panels. In this context, 69% of the fossil fuel can be saved when using the proposed hybrid configuration instead of the diesel generators that are currently installed in most remote regions in Algeria. Such a concept is very promising to meet the focus of renewable energy program announced in 2011.

  9. Economic and Environmental Assessment of a Renewable Stand-Alone Energy Supply System Using Multi-objective Optimization

    Lee, Dohyun; Han, Seulki; Kim, Jiyong Kim [Incheon National University, Incheon (Korea, Republic of)

    2017-06-15

    This study aims to propose a new optimization-based approach for design and analysis of the stand-alone hybrid energy supply system using renewable energy sources (RES). In the energy supply system, we include multiple energy production technologies such as Photovoltaics (PV), Wind turbine, and fossil-fuel-based AC generator along with different types of energy storage and conversion technologies such as battery and inverter. We then select six different regions of Korea to represent various characteristics of different RES potentials and demand profiles. We finally designed and analyzed the optimal RES stand-alone energy supply system in the selected regions using multiobjective optimization (MOOP) technique, which includes two objective functions: the minimum cost and the minimum CO{sub 2} emission. In addition, we discussed the feasibility and expecting benefits of the systems by comparing to conventional systems of Korea. As a result, the region of the highest RES potential showed the possibility to remarkably reduce CO{sub 2} emissions compared to the conventional system. Besides, the levelized cost of electricity (LCOE) of the RES-based energy system is identified to be slightly higher than conventional energy system: 0.35 and 0.46 $/kWh, respectively. However, the total life-cycle emission of CO{sub 2} (LCECO{sub 2}) can be reduced up to 470 gCO{sub 2}/kWh from 490 gCO{sub 2}/kWh of the conventional systems.

  10. Multi-objective optimal planning of the stand-alone microgrid system based on different benefit subjects

    Guo, Li; Wang, Nan; Lu, Hai; Li, Xialin; Wang, Chengshan

    2016-01-01

    As an important means to realize the energetic complementarity and improve the efficiency of renewable resources, the stand-alone microgrid (SAMG) system gains attention increasingly, especially in islands and remote areas. In this paper, considering the interest conflict of the distribution company and the distributed generation owner, a new multi-objective optimal planning model is formulated for medium voltage SAMG. Besides, to avoid the power constraint of distributed generation (DG) once the over-limit voltage occurs, a novel two-step power dispatch control method including the voltage regulation strategy is proposed, in which the absorption of distributed power by energy storage system (ESS) and the reactive power adjustment though its power control system are used to regulate voltage. The goal of this paper is to search the Pareto-optimal front of the site and capacity of DG as well as the contract price between both parties, and thus can provide effective references for practical planning of SAMG. Considering the high cost of ESS, the investment analysis of ESS is also discussed in the paper. - Highlights: • A multi-objective planning model based on different benefit subjects is proposed. • A two-step power dispatch method including the voltage regulation is proposed. • The economical efficiency of the proposed model is analyzed. • The effective reference for the stand-alone microgrid planning is provided.

  11. Hematology

    Ebbe, S.N.; Brecher, G.; Cohen, R.A.

    1981-01-01

    The program at the Donner Clinic in experimental megakaryocytopoiesia is described. Studies are being initiated to analyze blood gases and acid-base balance in patients with erythrocytosis and to correlate these measurements with levels of erythropoietin in blood and urine. The regulation of platelet production in humans and ways in which it may be aberrant in disease states are being investigated. Tracers used in this study include 75 Se-selenomethionine and 35 S-sodium sulfate

  12. Quality requirements for veterinary hematology analyzers in small animals-a survey about veterinary experts' requirements and objective evaluation of analyzer performance based on a meta-analysis of method validation studies: bench top hematology analyzer.

    Cook, Andrea M; Moritz, Andreas; Freeman, Kathleen P; Bauer, Natali

    2016-09-01

    Scarce information exists about quality requirements and objective evaluation of performance of large veterinary bench top hematology analyzers. The study was aimed at comparing the observed total error (TEobs ) derived from meta-analysis of published method validation data to the total allowable error (TEa ) for veterinary hematology variables in small animals based on experts' opinions. Ideally, TEobs should be hematology analyzers (ADVIA 2120; Sysmex XT2000iV, and CellDyn 3500) was calculated based on method validation studies published between 2005 and 2013 (n = 4). The percent TEobs = 2 * CV (%) + bias (%). The CV was derived from published studies except for the ADVIA 2120 (internal data), and bias was estimated from the regression equation. A total of 41 veterinary experts (19 diplomates, 8 residents, 10 postgraduate students, 4 anonymous specialists) responded. The proposed range of TEa was wide, but generally ≤ 20%. The TEobs was < TEa for all variables and analyzers except for canine and feline HGB (high bias, low CV) and platelet counts (high bias, high CV). Overall, veterinary bench top analyzers fulfilled experts' requirements except for HGB due to method-related bias, and platelet counts due to known preanalytic/analytic issues. © 2016 American Society for Veterinary Clinical Pathology.

  13. Use of appliances in stand-alone PV power supply systems: problems and solutions. Task 3 use of photovoltaic power systems in stand-alone and island applications

    Vallve, X.; Gafas, G. [IEA PVPS, Task 3 (Spain); Villoz, M. [IEA PVPS, Task 3 (Switzerland); Wilshaw, A. [IEA PVPS, Task 3 (United Kingdom); Jacquin, P. [IEA PVPS, Task 3 (France)

    2002-09-15

    In Stand-Alone Photovoltaic Systems (SAPV systems), special attention must be paid to the used appliances and loads. Inappropriate loads are very often the origin of PV system malfunction or failure. Start-up power peaks, or reactive power and harmonic distortion can cause system signal instability and protective devices will close the system down. A well-matched load together with a carefully selected choice of appliances can lead to significant savings in terms of reduced need for PV and electricity storage capacity. Conversely, inefficient appliances and processes, standby loads and inappropriate loads will increase the requirement for expensive PV and storage capacity. This paper presents a survey of real cases with load related problems in worldwide applications, their effect on quality and cost of the service and the solutions that were adopted and suggested alternative solutions. One of the main conclusions of the work is the importance to integrate the choice of the appliance while designing the SAPV system. (author)

  14. Hybrid Configuration of Darrieus and Savonius Rotors for Stand-alone Power Systems

    Wakui, Tetsuya; Tanzawa, Yoshiaki; Hashizume, Takumi; Nagao, Toshio

    The suitable hybrid configuration of Darrieus lift-type and Savonius drag-type rotors for stand-alone wind turbine-generator systems is discussed using our dynamic simulation model. Two types of hybrid configurations are taken up: Type-A installs the Savonius rotor inside the Darrieus rotor and Type-B installs the Savonius rotor outside the Darrieus rotor. The computed results of the output characteristics and the dynamic behaviors of the system operated at the maximum power coefficient points show that Type-A, which has fine operating behavior to wind speed changes and can be compactly designed because of a shorter rotational shaft, is an effective way for self-controlled stand-alone small-scale systems.

  15. Stand-Alone Microgrid Inverter Controller Design for Nonlinear, Unbalanced Load with Output Transformer

    Jae-Uk Lim

    2018-04-01

    Full Text Available This paper proposes a technique that compensates for unbalance and nonlinearity in microgrid inverters with power transformers operating in stand-alone mode. When a microgrid inverter is operating in stand-alone mode, providing high-quality power is very important. When an unbalanced, nonlinear load is connected, zero sequence current and negative sequence current occur, which leads to an unbalanced output voltage. This paper examines why the zero sequence component occurs differently depending on the structure of a three-phase transformer connected to the inverter output terminal, and it proposes a method for controlling the zero sequence component. It also uses a resonant controller to remove the harmonics that correspond to the negative sequence component and the nonlinear component. The proposed elements were verified by a Powersim (PSIM simulation.

  16. A Three-Port Topology Comparison for a Low Power Stand-Alone Photovoltaic System

    Mira Albert, Maria del Carmen; Knott, Arnold; Andersen, Michael A. E.

    2014-01-01

    Three-port converter (TPC) topologies for renewable energy systems aim to provide higher efficiency and power density than conventional cascaded structures. This work proposes an analytical comparison of different TPC topologies for a photovoltaic LED lamp stand-alone system. A comparison using c...... component stress factor (CSF) is performed, which gives a quantitative measure of the performance of the converter. The candidate topologies are compared to each other according to a defined LED lighting strategy and a solar irradiation profile.......Three-port converter (TPC) topologies for renewable energy systems aim to provide higher efficiency and power density than conventional cascaded structures. This work proposes an analytical comparison of different TPC topologies for a photovoltaic LED lamp stand-alone system. A comparison using...

  17. Analysis and controller design for stand-alone VSIs in synchronous reference frame

    Ramezani, Malek; Li, Shuhui; Golestan, Saeed

    2017-01-01

    -by-step graphical analysis and design approach for a three-phase stand-alone VSI system in the dq reference frame, which provides a clear systematic decoupling process to design the inner- and outer-loop current and voltage controllers, respectively. The closed-loop d- and q-axis output impedances of the stand......-alone VSI system by considering the coupling effects between axes are also formulated, modelled, and evaluated. The study investigates how the decoupling and compensating terms added in the current and voltage controllers affect the dynamic performance and output dq impedances of the VSI system. Simulation...... and hardware results verify the effectiveness of the graphic design and analysis strategy....

  18. A new approach for sizing stand alone photovoltaic systems based in neural networks

    Hontoria, L.; Aguilera, J. [Universidad de Jaen, Dept. de Electronica, Jaen (Spain); Zufiria, P. [UPM Ciudad Universitaria, Dept. de Matematica Aplicada a las Tecnologias de la Informacion, Madrid (Spain)

    2005-02-01

    Several methods for sizing stand alone photovoltaic (pv) systems has been developed. The more simplistic are called intuitive methods. They are a useful tool for a first approach in sizing stand alone photovoltaic systems. Nevertheless they are very inaccurate. Analytical methods use equations to describe the pv system size as a function of reliability. These ones are more accurate than the previous ones but they are also not accurate enough for sizing of high reliability. In a third group there are methods which use system simulations. These ones are called numerical methods. Many of the analytical methods employ the concept of reliability of the system or the complementary term: loss of load probability (LOLP). In this paper an improvement for obtaining LOLP curves based on the neural network called Multilayer Perceptron (MLP) is presented. A unique MLP for many locations of Spain has been trained and after the training, the MLP is able to generate LOLP curves for any value and location. (Author)

  19. Minimum cost solution of wind–photovoltaic based stand-alone power systems for remote consumers

    Kaldellis, J.K.; Zafirakis, D.; Kavadias, K.

    2012-01-01

    Renewable energy sources (RES) based stand-alone systems employing either wind or solar power and energy storage comprise a reliable energy alternative, on top of conventional diesel-electric generator sets, commonly used by remote consumers. However, such systems usually imply the need for oversizing and considerable energy storage requirements leading to relatively high costs. On the other hand, hybrid configurations that may exploit both wind and solar potential of a given area may considerably reduce energy storage capacity and improve the economic performance of the system. In this context, an integrated techno-economic methodology for the evaluation of hybrid wind–photovoltaic stand-alone power systems is currently developed, aiming at the designation of optimum configurations for a typical remote consumer, using economic performance criteria. For the problem investigation, the developed evaluation model is applied to four representative areas of the Greek territory with different wind potential characteristics in order to obtain optimum configurations on the basis of minimum initial investment, 10-year and 20-year total cost. According to the results obtained, the proposed solution is favorably compared with all other stand-alone energy alternatives, reflecting the ability of hybrid systems to adjust even in areas where the local RES potential is not necessarily of high quality. - Highlights: ► Wind- and PV-stand alone systems often imply use of extreme battery capacity. ► Hybrid wind–PV systems may reduce energy storage requirements and associated costs. ► An optimization methodology is developed, based on economic performance criteria. ► Methodology is applied to four Greek regions of different wind potential. ► Results obtained reflect the hybrid solution's advantages over other alternatives.

  20. Secure stand alone positive personnel identity verification system (SSA-PPIV)

    Merillat, P.D.

    1979-03-01

    The properties of a secure stand-alone positive personnel identity verification system are detailed. The system is designed to operate without the aid of a central computing facility and the verification function is performed in the absence of security personnel. Security is primarily achieved by means of data encryption on a magnetic stripe badge. Several operational configurations are discussed. Advantages and disadvantages of this system compared to a central computer driven system are detailed

  1. MOSFET Loss Evaluation for a Low-Power Stand-Alone Photovoltaic-LED System

    Mira Albert, Maria del Carmen; Knott, Arnold; Andersen, Michael A. E.

    2015-01-01

    This paper presents a performance evaluation and comparison of state-of-the-art low voltage Si MOSFETs for a stand-alone photovoltaic-LED Light to Light (LtL) system. The complete system is formed by two cascaded converters that will be optimized for a determined solar irradiation and LED...... illumination profiles. The comparison is performed based on dynamic characterization and evaluation of the devices energy loss at different current levels....

  2. Stand-Alone Solar Organic Rankine Cycle Water Pumping System and Its Economic Viability in Nepal

    Suresh Baral; Kyung Chun Kim

    2015-01-01

    The current study presents the concept of a stand-alone solar organic Rankine cycle (ORC) water pumping system for rural Nepalese areas. Experimental results for this technology are presented based on a prototype. The economic viability of the system was assessed based on solar radiation data of different Nepalese geographic locations. The mechanical power produced by the solar ORC is coupled with a water pumping system for various applications, such as drinking and irrigation. The thermal ef...

  3. Methodology for the design of a stand-alone photovoltaic power supply

    López Seguel, Julio; Seleme Junior, Seleme Isaac; Donoso-Garcia, Pedro F; Ferreira Morais, Lenin Martins; Cabaleiro Cortizo, Porfirio; Severo Mendes, Marcos A

    2013-01-01

    This paper presents a complete methodology for the design of an autonomous photovoltaic system to maximize the use of solar energy. It is a method that prioritizes the best cost-effective choice at every step of the project. In order to ensure the proper use and extended battery life time, a control strategy for charging the batteries is proposed. Experimental results are provided for a stand-alone photovoltaic system with low electrical power, intended primarily for the illumination and basi...

  4. Modeling, Design and Simulation of Stand-Alone Photovoltaic Power Systems with Battery Storage

    Abd Essalam BADOUD

    2013-06-01

    Full Text Available Stand alone renewable energy based on photovoltaic systems accompanied with battery storage system are beginning to play an important role over the world to supply power to remote areas. The objective of the study reported in this paper is to elaborate and design a bond graphs model for sizing stand-alone domestic solar photovoltaic electricity systems and simulating the performance of the systems in a tropical climate. The systems modelled consist of an array of PV modules, a lead-acid battery, and a number of direct current appliances. This paper proposes the combination of lead acid battery system with a typical stand alone photovoltaic energy system under variable loads. The main activities of this work purpose to establish library graphical models for each individual component of standalone photovoltaic system. Control strategy has been considered to achieve permanent power supply to the load via photovoltaic/battery based on the power available from the sun. The complete model was simulated under two testing including sunny and cloudy conditions. Simulation of the system using Symbols software was performed and the results of simulation show the superior stable control system and high efficiency. These results have been contrasted with real measured data from a measurement campaign plant carried on electrical engineering laboratory of Grenoble using various interconnection schemes are presented.

  5. Structure Optimization of Stand-Alone Renewable Power Systems Based on Multi Object Function

    Jae-Hoon Cho

    2016-08-01

    Full Text Available This paper presents a methodology for the size optimization of a stand-alone hybrid PV/wind/diesel/battery system while considering the following factors: total annual cost (TAC, loss of power supply probability (LPSP, and the fuel cost of the diesel generator required by the user. A new optimization algorithm and an object function (including a penalty method are also proposed; these assist with designing the best structure for a hybrid system satisfying the constraints. In hybrid energy system sources such as photovoltaic (PV, wind, diesel, and energy storage devices are connected as an electrical load supply. Because the power produced by PV and wind turbine sources is dependent on the variation of the resources (sun and wind and the load demand fluctuates, such a hybrid system must be able to satisfy the load requirements at any time and store the excess energy for use in deficit conditions. Therefore, reliability and cost are the two main criteria when designing a stand-alone hybrid system. Moreover, the operation of a diesel generator is important to achieve greater reliability. In this paper, TAC, LPSP, and the fuel cost of the diesel generator are considered as the objective variables and a hybrid teaching–learning-based optimization algorithm is proposed and used to choose the best structure of a stand-alone hybrid PV/wind/diesel/battery system. Simulation results from MATLAB support the effectiveness of the proposed method and confirm that it is more efficient than conventional methods.

  6. Optimization of stand-alone photovoltaic systems with hydrogen storage for total energy self-sufficiency

    Lund, P D [Helsinki Univ. of Technology, Espoo (Finland). Dept. of Technical Physics

    1991-01-01

    A new method for optimization of stand-alone photovoltaic-hydrogen energy systems is presented. The methodology gives the optimum values for the solar array and hydrogen storage size for any given system configuration and geographical site. Sensitivity analyses have been performed to study the effect of subsystem efficiencies on the total system performance and sizing, and also to identify possibilities for further improvements. Optimum system configurations have also been derived. The results indicate that a solar-hydrogen energy system is a very promising potential alternative for low power applications requiring a total electricity self-sufficiency. (Author).

  7. A Simple Sizing Algorithm for Stand-Alone PV/Wind/Battery Hybrid Microgrids

    Jing Li

    2012-12-01

    Full Text Available In this paper, we develop a simple algorithm to determine the required number of generating units of wind-turbine generator and photovoltaic array, and the associated storage capacity for stand-alone hybrid microgrid. The algorithm is based on the observation that the state of charge of battery should be periodically invariant. The optimal sizing of hybrid microgrid is given in the sense that the life cycle cost of system is minimized while the given load power demand can be satisfied without load rejection. We also report a case study to show the efficacy of the developed algorithm.

  8. Lossy Data Aggregation with Network Coding in Stand-Alone Wireless Sensor Networks

    Madsen, Tatiana Kozlova

    2011-01-01

    in chemical plants, etc. Given resource constrained operation of a sensor network where the nodes are battery powered and buffer sizes are limited, efficient methods for in-network data storage abd it subsequent fast and reliable transmission to a gateway is desirable. To save scarse resources and to prolong......This work focuses on a special type of wireless sensor networks (WSNs) that we refer to as a stand alone network. These netwoks operate in harsh and extreme environments where data collection is done only occasionally. Typical examples include habitat monitoring systems, monitoring systems...

  9. Boost converter with combined control loop for a stand-alone photovoltaic battery charge system

    Mira Albert, Maria del Carmen; Knott, Arnold; Thomsen, Ole Cornelius

    2013-01-01

    frequency avoids perturbations in the load being propagated to the photovoltaic panel and thus deviating the operating point. Linearization of the photovoltaic panel and converter state-space modeling is performed. In order to achieve stable operation under all operating conditions, the photovoltaic panel......The converter control scheme plays an important role in the performance of maximum power point tracking (MPPT) algorithms. In this paper, an input voltage control with double loop for a stand-alone photovoltaic system is designed and tested. The inner current control loop with high crossover...

  10. System design optimization for stand-alone photovoltaic systems sizing by using superstructure model

    Azau, M A M; Jaafar, S; Samsudin, K

    2013-01-01

    Although the photovoltaic (PV) systems have been increasingly installed as an alternative and renewable green power generation, the initial set up cost, maintenance cost and equipment mismatch are some of the key issues that slows down the installation in small household. This paper presents the design optimization of stand-alone photovoltaic systems using superstructure model where all possible types of technology of the equipment are captured and life cycle cost analysis is formulated as a mixed integer programming (MIP). A model for investment planning of power generation and long-term decision model are developed in order to help the system engineer to build a cost effective system.

  11. Development of a microprocessor controller for stand-alone photovoltaic power systems

    Millner, A. R.; Kaufman, D. L.

    1984-01-01

    A controller for stand-alone photovoltaic systems has been developed using a low power CMOS microprocessor. It performs battery state of charge estimation, array control, load management, instrumentation, automatic testing, and communications functions. Array control options are sequential subarray switching and maximum power control. A calculator keypad and LCD display provides manual control, fault diagnosis and digital multimeter functions. An RS-232 port provides data logging or remote control capability. A prototype 5 kW unit has been built and tested successfully. The controller is expected to be useful in village photovoltaic power systems, large solar water pumping installations, and other battery management applications.

  12. Design, building and testing of a stand alone fuel cell hybrid system

    Segura, F.; Duran, E.; Andujar, J.M. [Department of Electronic, Computer Science and Automatic Engineering, University of Huelva (Spain)

    2009-08-01

    This paper designs, sizes, builds and tests a stand alone fuel cell hybrid system made up of a fuel cell stack and a battery bank. This system has been sized to supply a typical telecommunication load profile, but moreover, the system can supply other profiles. For this purpose, a modular low cost electronic load bank has been designed and built. This load bank allows the power demand to be chosen by selecting different solid state relays. Moreover, a virtual instrument based on NI Labview {sup registered} has been designed to select the load power demand from the computer. (author)

  13. State Feedback Decoupling with In-Loop Lead Compensator in Stand-Alone VSIs

    Federico, de Bosio; Pastorelli, Michele; de Sousa Ribeiro, Luiz Antonio

    2016-01-01

    The performance of current and voltage regulators during transients and steady-state is of primary concern for power converters intended for stand-alone applications. Dynamics performance and command tracking capability are enhanced by actively decoupling the controlled states variables. To further...... widen the current loop bandwidth while still preserving a well-damped system a lead compensator structure on the forward loop is proposed. A 3 kHz bandwidth with 0.707 damping factor is achieved for the inner current controller. Accordingly, also the voltage regulator bandwidth can be widen, thus...

  14. Information systems for the materials management department: stand-alone and enterprise resource planning systems.

    2005-03-01

    Materials management information systems (MMISs) incorporate information tools that hospitals can use to automate certain business processes, increase staff compliance with these processes, and identify opportunities for cost savings. Recently, there has been a push by hospital administration to purchase enterprise resource planning (ERP) systems, information systems that promise to integrate many more facets of healthcare business. We offer this article to help materials managers, administrators, and others involved with information system selection understand the changes that have taken place in materials management information systems, decide whether they need a new system and, if so, whether a stand-alone MMIS or an ERP system will be the best choice.

  15. Simulation of stand alone PV systems; Dokuritsugata taiyoko hatsuden system no simulation

    Tsuda, I.; Sakuta, K. [Electrotechnical Laboratory, Tsukuba (Japan); Oshiro, T. [Japan Quality Assurance Organization, Tokyo (Japan); Kurokawa, K. [Tokyo University of Agriculture and Technology, Tokyo (Japan)

    1997-11-25

    Studies are performed to develop a simulation program for a stand-alone photovoltaic power generation system equipped with a lead acid battery. In this stand-alone photovoltaic power generation system, the load is connected in shunt with the solar cell array output through the intermediary of a lead acid battery and inverter. The program is a model in which the solar cell model is built taking parallel resistance into account, and the temperature-dependence of the constants is described using approximations experimentally obtained by Solar Techno Center of JQA (Japan Quality Assurance Organization), Hamamatsu. Insolation data for the model is described using METPV compiled by Japan Weather Association, and load data is described using data actually measured at Shizuoka. This program is compared with the data of operation at Hamamatsu, and the result is almost satisfactory. Simulations are conducted at five typical locations in Japan using this program, and it is found that the array load matching correction factor is dependent on seasonal changes rather than locality, that the battery contribution rate does not change much throughout the year, and that it is not dependent on locality. 5 refs., 7 figs., 3 tabs.

  16. Modified Chaos Particle Swarm Optimization-Based Optimized Operation Model for Stand-Alone CCHP Microgrid

    Fei Wang

    2017-07-01

    Full Text Available The optimized dispatch of different distributed generations (DGs in stand-alone microgrid (MG is of great significance to the operation’s reliability and economy, especially for energy crisis and environmental pollution. Based on controllable load (CL and combined cooling-heating-power (CCHP model of micro-gas turbine (MT, a multi-objective optimization model with relevant constraints to optimize the generation cost, load cut compensation and environmental benefit is proposed in this paper. The MG studied in this paper consists of photovoltaic (PV, wind turbine (WT, fuel cell (FC, diesel engine (DE, MT and energy storage (ES. Four typical scenarios were designed according to different day types (work day or weekend and weather conditions (sunny or rainy in view of the uncertainty of renewable energy in variable situations and load fluctuation. A modified dispatch strategy for CCHP is presented to further improve the operation economy without reducing the consumers’ comfort feeling. Chaotic optimization and elite retention strategy are introduced into basic particle swarm optimization (PSO to propose modified chaos particle swarm optimization (MCPSO whose search capability and convergence speed are improved greatly. Simulation results validate the correctness of the proposed model and the effectiveness of MCPSO algorithm in the optimized operation application of stand-alone MG.

  17. Design of a Stand-Alone Photovoltaic Model for Home Lightings and Clean Environment

    Ani, Vincent Anayochukwu, E-mail: vincent_ani@yahoo.com [Department of Electronic Engineering, University of Nigeria, Nsukka (Nigeria)

    2016-01-11

    This paper gives a well-documented health risk of fuel-based lighting (kerosene lamps and fuel-powered generators) and proposed a design of a stand-alone solar PV system for sustainable home lightings in rural Nigerian area. The design was done in three different patterns of electricity consumptions with energy efficient lightings (EELs) using two different battery types (Rolls Surrette 6CS25PS and Hoppecke 10 OpzS 1000) on; (i) judicious power consumption, (ii) normal power consumption, and (iii) excess power consumption; and compared them with the incandescent light bulb consumption. The stand-alone photovoltaic energy systems were designed to match the rural Nigerian sunlight and weather conditions to meet the required lightings of the household. The objective function and constraints for the design models were formulated and optimization procedures were used to demonstrate the best solution (reliability at the lowest lifecycle cost). Initial capital costs as well as annualized costs over 5, 10, 15, 20, and 25 years were quantified and documented. The design identified the most cost-effective and reliable solar and battery array among the patterns of electricity consumption with EEL options (judicious power consumption, normal power consumption, and excess power consumption).

  18. Design of Stand-Alone Hybrid Power Generation System at Brumbun Beach Tulungagung East Java

    Rahmat, A. N.; Hidayat, M. N.; Ronilaya, F.; Setiawan, A.

    2018-04-01

    Indonesian government insists to optimize the use of renewable energy resources in electricity generation. One of the efforts is launching Independent Energy Village plan. This program aims to fulfill the need of electricity for isolated or remote villages in Indonesia. In order to support the penetration of renewable energy resources in electricity generation, a hybrid power generation system is developed. The simulation in this research is based on the availability of renewable energy resources in Brumbun beach, Tulungagung, East Java. Initially, the electricity was supplied through stand-alone electricity generations which are installed at each house. Hence, the use of electricity between 5 p.m. – 9 p.m. requires high operational costs. Based on the problem above, this research is conducted to design a stand-alone hybrid electricity generation system, which may consist of diesel, wind, and photovoltaic. The design is done by using HOMER software to optimize the use of electricity from renewable resources and to reduce the operation of diesel generation. The combination of renewable energy resources in electricity generation resulted in NPC of 44.680, COE of 0,268, and CO2 emissions of 0,038 % much lower than the use of diesel generator only.

  19. Fuzzy logic control of stand-alone photovoltaic system with battery storage

    Lalouni, S.; Rekioua, D.; Rekioua, T.; Matagne, E.

    Photovoltaic energy has nowadays an increased importance in electrical power applications, since it is considered as an essentially inexhaustible and broadly available energy resource. However, the output power provided via the photovoltaic conversion process depends on solar irradiation and temperature. Therefore, to maximize the efficiency of the photovoltaic energy system, it is necessary to track the maximum power point of the PV array. The present paper proposes a maximum power point tracker (MPPT) method, based on fuzzy logic controller (FLC), applied to a stand-alone photovoltaic system. It uses a sampling measure of the PV array power and voltage then determines an optimal increment required to have the optimal operating voltage which permits maximum power tracking. This method carries high accuracy around the optimum point when compared to the conventional one. The stand-alone photovoltaic system used in this paper includes two bi-directional DC/DC converters and a lead-acid battery bank to overcome the scare periods. One converter works as an MPP tracker, while the other regulates the batteries state of charge and compensates the power deficit to provide a continuous delivery of energy to the load. The Obtained simulation results show the effectiveness of the proposed fuzzy logic controller.

  20. A sizing method for stand-alone PV installations with variable demand

    Posadillo, R. [Grupo de Investigacion en Energias y Recursos Renovables, Dpto. de Fisica Aplicada, E.P.S., Universidad de Cordoba, Avda. Menendez Pidal s/n, 14004 Cordoba (Spain); Lopez Luque, R. [Grupo de Investigacion de Fisica Para las Energias y Recursos Renovables, Dpto. de Fisica Aplicada, Edificio C2 Campus de Rabanales, 14071 Cordoba (Spain)

    2008-05-15

    The practical applicability of the considerations made in a previous paper to characterize energy balances in stand-alone photovoltaic systems (SAPV) is presented. Given that energy balances were characterized based on monthly estimations, the method is appropriate for sizing installations with variable monthly demands and variable monthly panel tilt (for seasonal estimations). The method presented is original in that it is the only method proposed for this type of demand. The method is based on the rational utilization of daily solar radiation distribution functions. When exact mathematical expressions are not available, approximate empirical expressions can be used. The more precise the statistical characterization of the solar radiation on the receiver module, the more precise the sizing method given that the characterization will solely depend on the distribution function of the daily global irradiation on the tilted surface H{sub g{beta}}{sub i}. This method, like previous ones, uses the concept of loss of load probability (LLP) as a parameter to characterize system design and includes information on the standard deviation of this parameter ({sigma}{sub LLP}) as well as two new parameters: annual number of system failures (f) and the standard deviation of annual number of system failures ({sigma}{sub f}). This paper therefore provides an analytical method for evaluating and sizing stand-alone PV systems with variable monthly demand and panel inclination. The sizing method has also been applied in a practical manner. (author)

  1. Design of a Stand-Alone Photovoltaic (PV Models for Home Lightings and Clean Environment

    Vincent Anayochukwu Ani

    2016-01-01

    Full Text Available This paper gives a well-documented health risks of fuel-based lighting (kerosene lamps and fuel-powered generators and proposed a design of a stand-alone solar PV system for sustainable home lightings in rural Nigerian area. The design was done in three different patterns of electricity consumptions with energy efficient lightings (EELs using two different battery types (Rolls Surrette 6CS25PS and hoppecke 10 OpzS 1000 on; i judicious power consumption, ii normal power consumption, iii excess power consumption; and compared them with the incandescent light bulb consumption. The stand-alone photovoltaic energy systems were designed to match the rural Nigerian sunlight and weather conditions to meet the required lightings of the household. The objective function and constraints for the design models were formulated and optimization procedure were used to demonstrate the best solution (reliability at the lowest lifecycle cost. Initial capital costs as well as annualized costs over 5, 10, 15, 20, and 25 years were quantified and documented. The design identified the most cost-effective and reliable solar and battery array among the patterns of electricity consumption with energy efficient lighting options (judicious power consumption, normal power consumption, and excess power consumption.

  2. International market assessment of stand-alone photovoltaic power systems for cottage industry applications

    Philippi, T. M.

    1981-01-01

    The final result of an international assessment of the market for stand-alone photovoltaic systems in cottage industry applications is reported. Nonindustrialized countries without centrally planned economies were considered. Cottage industries were defined as small rural manufacturers, employing less than 50 people, producing consumer and simple products. The data to support this analysis were obtained from secondary and expert sources in the U.S. and in-country field investigations of the Philippines and Mexico. The near-term market for photovoltaics for rural cottage industry applications appears to be limited to demonstration projects and pilot programs, based on an in-depth study of the nature of cottage industry, its role in the rural economy, the electric energy requirements of cottage industry, and a financial analysis of stand-alone photovoltaic systems as compared to their most viable competitor, diesel driven generators. Photovoltaics are shown to be a better long-term option only for very low power requirements. Some of these uses would include clay mixers, grinders, centrifuges, lathes, power saws and lighting of a workshop.

  3. Coordination Control Strategy for AC/DC Hybrid Microgrids in Stand-Alone Mode

    Dwi Riana Aryani

    2016-06-01

    Full Text Available Interest in DC microgrids is rapidly increasing along with the improvement of DC power technology because of its advantages. To support the integration process of DC microgrids with the existing AC utility grids, the form of hybrid AC/DC microgrids is considered for higher power conversion efficiency, lower component cost and better power quality. In the system, AC and DC portions are connected through interlink bidirectional AC/DC converters (IC with a proper control system and power management. In the stand-alone operation mode of AC/DC hybrid microgrids, the control of power injection through the IC is crucial in order to maintain the system security. This paper mainly deals with a coordination control strategy of IC and a battery energy storage system (BESS converter under stand-alone operation. A coordinated control strategy for the IC, which considers the state of charge (SOC level of BESS and the load shedding scheme as the last resort, is proposed to obtain better power sharing between AC and DC subgrids. The scheme will be tested with a hybrid AC/DC microgrid, using the tool of the PSCAD/EMTDC software.

  4. International market assessment of stand-alone photovoltaic power systems for cottage industry applications

    Philippi, T. M.

    1981-11-01

    The final result of an international assessment of the market for stand-alone photovoltaic systems in cottage industry applications is reported. Nonindustrialized countries without centrally planned economies were considered. Cottage industries were defined as small rural manufacturers, employing less than 50 people, producing consumer and simple products. The data to support this analysis were obtained from secondary and expert sources in the U.S. and in-country field investigations of the Philippines and Mexico. The near-term market for photovoltaics for rural cottage industry applications appears to be limited to demonstration projects and pilot programs, based on an in-depth study of the nature of cottage industry, its role in the rural economy, the electric energy requirements of cottage industry, and a financial analysis of stand-alone photovoltaic systems as compared to their most viable competitor, diesel driven generators. Photovoltaics are shown to be a better long-term option only for very low power requirements. Some of these uses would include clay mixers, grinders, centrifuges, lathes, power saws and lighting of a workshop.

  5. Robust Power Management Control for Stand-Alone Hybrid Power Generation System

    Kamal, Elkhatib; Adouane, Lounis; Aitouche, Abdel; Mohammed, Walaa

    2017-01-01

    This paper presents a new robust fuzzy control of energy management strategy for the stand-alone hybrid power systems. It consists of two levels named centralized fuzzy supervisory control which generates the power references for each decentralized robust fuzzy control. Hybrid power systems comprises: a photovoltaic panel and wind turbine as renewable sources, a micro turbine generator and a battery storage system. The proposed control strategy is able to satisfy the load requirements based on a fuzzy supervisor controller and manage power flows between the different energy sources and the storage unit by respecting the state of charge and the variation of wind speed and irradiance. Centralized controller is designed based on If-Then fuzzy rules to manage and optimize the hybrid power system production by generating the reference power for photovoltaic panel and wind turbine. Decentralized controller is based on the Takagi-Sugeno fuzzy model and permits us to stabilize each photovoltaic panel and wind turbine in presence of disturbances and parametric uncertainties and to optimize the tracking reference which is given by the centralized controller level. The sufficient conditions stability are formulated in the format of linear matrix inequalities using the Lyapunov stability theory. The effectiveness of the proposed Strategy is finally demonstrated through a SAHPS (stand-alone hybrid power systems) to illustrate the effectiveness of the overall proposed method. (paper)

  6. Design of a Stand-Alone Photovoltaic Model for Home Lightings and Clean Environment

    Ani, Vincent Anayochukwu

    2016-01-01

    This paper gives a well-documented health risk of fuel-based lighting (kerosene lamps and fuel-powered generators) and proposed a design of a stand-alone solar PV system for sustainable home lightings in rural Nigerian area. The design was done in three different patterns of electricity consumptions with energy efficient lightings (EELs) using two different battery types (Rolls Surrette 6CS25PS and Hoppecke 10 OpzS 1000) on; (i) judicious power consumption, (ii) normal power consumption, and (iii) excess power consumption; and compared them with the incandescent light bulb consumption. The stand-alone photovoltaic energy systems were designed to match the rural Nigerian sunlight and weather conditions to meet the required lightings of the household. The objective function and constraints for the design models were formulated and optimization procedures were used to demonstrate the best solution (reliability at the lowest lifecycle cost). Initial capital costs as well as annualized costs over 5, 10, 15, 20, and 25 years were quantified and documented. The design identified the most cost-effective and reliable solar and battery array among the patterns of electricity consumption with EEL options (judicious power consumption, normal power consumption, and excess power consumption).

  7. Input of biomass in stand-alone small-scale installations for power generation. Calculation of the financial gap

    Van Tilburg, X.; De Vries, H.J.; Pfeiffer, A.E.; Beekes, M.; Cleijne, J.W.

    2005-09-01

    A number of new initiatives in which bio-oil is used in stand-alone plants for power generation has been reviewed. The question to be answered is whether the reference case for stand alone biomass projects based on burning of wood chips can still be considered representative for the costs and benefits in this category. ECN, in cooperation with KEMA, have determined the financial gap between the costs and benefits of projects in which bio-oil is used in stand alone plants for power generation. The ranges and reference case for bio-oil in stand alone applications show that these projects have a substantially lower financial gap than the current reference case based on wood chips [nl

  8. Charactrization of a Li-ion battery based stand-alone a-Si photovoltaic system

    Hamid Vishkasougheh, Mehdi; Tunaboylu, Bahadir

    2014-01-01

    Highlights: • An Li-ion battery based stand-alone a-Si PV was designed. The system composed of three a-Si panels with an efficiency of 7% and 40 cells of LFP batteries. • Effects of solar radiation and environmental temperature for three cities, Istanbul, Ankara, and Adana, have been investigated on a-Si panels. • Using transition formulas BSPV outputs are predictable for any location out of standard test condition. - Abstract: The number of photovoltaic (PV) system installations is increasing rapidly. As more people learn about this versatile and often cost-effective power option, this trend will accelerate. This document presents a recommended design for a battery based stand-alone photovoltaic system (BSPV). BSPV system has the ability to be applied in different areas, including warning signals, lighting, refrigeration, communication, residential water pumping, remote sensing, and cathodic protection. The presented calculation method gives a proper idea for a system sizing technique. Based on application load, different scenarios are possible for designing a BSPV system. In this study, a battery based stand-alone system was designed. The electricity generation part is three a-Si panels, which are connected in parallel, and for the storage part LFP (lithium iron phosphate) battery was used. The high power LFP battery packs are 40 cells each 8S5P (configured 8 series 5 parallel). Each individual pack weighs 0.5 kg and is 25.6 V. In order to evaluate the efficiency of a-Si panels with respect to the temperature and the solar irradiation, cities of Istanbul, Ankara and Adana in Turkey were selected. Temperature and solar irradiation were gathered from reliable sources and by using translation equations, current and voltage output of panels were calculated. As a result of these calculations, current and energy outputs were computed by considering an average efficient solar irradiation time value per day in Turkey. The calculated power values were inserted to a

  9. Charactrization of a Li-ion battery based stand-alone a-Si photovoltaic system

    Hamid Vishkasougheh, Mehdi, E-mail: mehdi.hamid2@gmail.com [Istanbul Sehir University, Kubakisi Caddesi, No: 27, Altunizade, Uskudar, Istanbul 34662 (Turkey); Tunaboylu, Bahadir [Istanbul Sehir University, Kubakisi Caddesi, No: 27, Altunizade, Uskudar, Istanbul 34662 (Turkey); Marmara Research Center, Materials Institute, PO Box 21, Gebze, Kocaeli 41470 (Turkey)

    2014-11-01

    Highlights: • An Li-ion battery based stand-alone a-Si PV was designed. The system composed of three a-Si panels with an efficiency of 7% and 40 cells of LFP batteries. • Effects of solar radiation and environmental temperature for three cities, Istanbul, Ankara, and Adana, have been investigated on a-Si panels. • Using transition formulas BSPV outputs are predictable for any location out of standard test condition. - Abstract: The number of photovoltaic (PV) system installations is increasing rapidly. As more people learn about this versatile and often cost-effective power option, this trend will accelerate. This document presents a recommended design for a battery based stand-alone photovoltaic system (BSPV). BSPV system has the ability to be applied in different areas, including warning signals, lighting, refrigeration, communication, residential water pumping, remote sensing, and cathodic protection. The presented calculation method gives a proper idea for a system sizing technique. Based on application load, different scenarios are possible for designing a BSPV system. In this study, a battery based stand-alone system was designed. The electricity generation part is three a-Si panels, which are connected in parallel, and for the storage part LFP (lithium iron phosphate) battery was used. The high power LFP battery packs are 40 cells each 8S5P (configured 8 series 5 parallel). Each individual pack weighs 0.5 kg and is 25.6 V. In order to evaluate the efficiency of a-Si panels with respect to the temperature and the solar irradiation, cities of Istanbul, Ankara and Adana in Turkey were selected. Temperature and solar irradiation were gathered from reliable sources and by using translation equations, current and voltage output of panels were calculated. As a result of these calculations, current and energy outputs were computed by considering an average efficient solar irradiation time value per day in Turkey. The calculated power values were inserted to a

  10. Loss-of-load probabilities for stand-alone photovoltaic systems

    Klein, S.A.; Beckman, W.A.

    1989-01-01

    A general method is presented for estimating the loss-of-load probability of stand-alone photovoltaic systems. The method was developed by correlating simulation results. The simulations were driven with synthetic radiation sequences having the same statistical significance as available historical data. The methods assumes a constant nighttime load and accounts for the distribution and persistence in daily solar radiation data. It is shown that the 10 year average performance of systems having loss-of-load probabilities less than about 0.01 can vary greatly from one ten year period to the next and thereby cannot be considered realistic performance estimates of a system during its lifetime. (author). 26 refs, 15 figs, 4 tabs

  11. Stand-alone version of the 11kW Gaia wind turbine

    Bindner, H.; Rosas, P.A.C.; Teodorescu, R.; Blaabjerg, F.

    2004-09-15

    This report describes the development of a stand-alone version of the 11kW Gaia wind turbine. Various possible configurations are investigated and a configuration using a back-to-back converter is chosen. A model is developed for controller design of the fast controllers of the unit. Controllers are designed and a prototype is built for testing. The report documents the performance of the prototype through measurements done on the full scale prototype installed in a test facility where it has been tested both as a standalone unit and in parallel with a diesel genset. For system wide power quality assessment and controller design a dynamic performance assessment model has been developed. (au)

  12. Size optimization of stand-alone photovoltaic (PV) room air conditioners

    Chen, Chien-Wei; Zahedi, A.

    2006-01-01

    Sizing of a stand-alone PV system determines the main cost of the system. PV electricity cost is determined by the amount of solar energy received, hence the actual climate and weather conditions such as solar irradiance and ambient temperature affect the size required and cost of the system. Air conditioning demand also depends on the weather conditions. Therefore, sizing a PV powered air conditioner must consider the characteristics of local climate and temperature. In this paper, sizing procedures and special considerations for air conditioning under Melbourne's climatic conditions is presented. The reliability of various PV-battery size combinations is simulated by MATLAB. As a result, excellent system performance can be predicated.(Author)

  13. Integrated Three-Port DC-DC Converter for Photovoltaic (PV) Battery Stand-alone Systems

    Ouyang, Ziwei; Andersen, Michael A. E.

    2016-01-01

    of solar energy. Moreover, a novel transformer configuration enables variable turns ratio controlled by the phase between the two current excitations subjected to the primary windings, allowing a wider input/output range. 1 kW experimental prototype has been built to demonstrate a wellmanaged power flow......Several power sources such as PV solar arrays and battery are often used to manage the power flow for a photovoltaic (PV) based stand-alone power system due to the fluctuation nature of solar energy resource, and deliver a continuous power to the users in an appropriate form. Traditionally, three...... different single-input single-output (SISO) dc/dc converters would have been used. To reduce the cost and improve the power density of the system, an integrated three-port isolated dc/dc converter is proposed in this paper. It can realize all functions of the energy delivery due to the fluctuation nature...

  14. Solar pv fed stand-alone excitation system of a synchronous machine for reactive power generation

    Sudhakar, N.; Jain, Siddhartha; Jyotheeswara Reddy, K.

    2017-11-01

    This paper presents a model of a stand-alone solar energy conversion system based on synchronous machine working as a synchronous condenser in overexcited state. The proposed model consists of a Synchronous Condenser, a DC/DC boost converter whose output is fed to the field of the SC. The boost converter is supplied by the modelled solar panel and a day time variable irradiance is fed to the panel during the simulation time. The model also has one alternate source of rechargeable batteries for the time when irradiance falls below a threshold value. Also the excess power produced when there is ample irradiance is divided in two parts and one is fed to the boost converter while other is utilized to recharge the batteries. A simulation is done in MATLAB-SIMULINK and the obtained results show the utility of such modelling for supplying reactive power is feasible.

  15. Use of small stand-alone Internet nodes as a distributed control system

    Goodwin, Robert W.; Kucera, Michael J.; Shea, Michael F.

    1994-12-01

    For several years, the standard model for accelerator control systems has been workstation consoles connected to VME local stations by a Local Area Network with analog and digital data being accessed via a field bus to custom I/O interface electronics. Commercially available hardware has now made it possible to implement a small stand-alone data acquisition station that combines the LAN connection, the computer, and the analog and digital I/O interface on a single board. This eliminates the complexity of a field bus and the associated proprietary I/O hardware. A minimum control system is one data acquisition station and a Macintosh or workstation console, both connected to the network; larger systems have more consoles and nodes. An implementation of this architecture is described along with performance and operational experience.

  16. Stand-Alone Photovoltaic System Operation with Energy Management and Fault Tolerant

    Jmashidpour, Ehsan; Poure, Philippe; Gholipour, E.; Saadate, Shahrokh

    2017-01-01

    This paper presents a stand-alone photovoltaic (PV) system with a fault tolerant operation capability. An energy management method is provided to keep the balance between produced and consumed energy instantaneously. As the storage element, an Ultra-Capacitor (UC) pack is used for facing high frequency variation of the load/source, and batteries are in charge of slow load /source variations. A Maximum Power Point Tracking (MPPT) algorithm is applied to control the boost converter of the PV source to achieve the maximum power. In order to improve the micro-grid service continuity and reliability, a fast fault diagnosis method based on the converter current shape for PV source is applied. Finally, the validity of the proposed energy management and the fault diagnosis method is confirmed by the simulation and experimental results. (author)

  17. Power quality improvement of a stand-alone power system subjected to various disturbances

    Lone, Shameem Ahmad; Mufti, Mairaj Ud-Din

    In wind-diesel stand-alone power systems, the disturbances like random nature of wind power, turbulent wind, sudden changes in load demand and the wind park disconnection effect continuously the system voltage and frequency. The satisfactory operation of such a system is not an easy task and the control design has to take in to account all these subtleties. For maintaining the power quality, generally, a short-term energy storage device is used. In this paper, the performance of a wind-diesel system associated with a superconducting magnetic energy storage (SMES) system is studied. The effect of installing SMES at wind park bus/load bus, on the system performance is investigated. To control the exchange of real and reactive powers between the SMES unit and the wind-diesel system, a control strategy based on fuzzy logic is proposed. The dynamic models of the hybrid power system for most common scenarios are developed and the results presented.

  18. JAERI Fuel Cleanup System (J-FCU) stand-alone tritium test at the TSTA

    Konishi, Satoshi; Hayashi, Takumi; Inoue, Masahiko

    1993-03-01

    JAERI designed, fabricated, and installed the JAERI Fuel Cleanup System (J-FCU) as a subsystem of simulated fusion fuel loop at the TSTA. The main function of the J-FCU is to purify and to recover hydrogen isotopes from simulated plasma exhaust while exhausting tritium free impurities. After a lot of deuterium tests, a first tritium test of the J-FCU was performed with one gram of tritium at the TSTA on June 1991. Main purpose of this test was to evaluate the total integrity and function of the J-FCU system with a DT mixture. Through this test, the J-FCU was operated well and its function with tritium was demonstrated. This report describes the detail test results of the J-FCU first tritium test and discuss its functions by stand-alone mode. Residual tritium inventory of the J-FCU system was also discussed. (author)

  19. System Simulation by Recursive Feedback: Coupling a Set of Stand-Alone Subsystem Simulations

    Nixon, D. D.

    2001-01-01

    Conventional construction of digital dynamic system simulations often involves collecting differential equations that model each subsystem, arran g them to a standard form, and obtaining their numerical gin solution as a single coupled, total-system simultaneous set. Simulation by numerical coupling of independent stand-alone subsimulations is a fundamentally different approach that is attractive because, among other things, the architecture naturally facilitates high fidelity, broad scope, and discipline independence. Recursive feedback is defined and discussed as a candidate approach to multidiscipline dynamic system simulation by numerical coupling of self-contained, single-discipline subsystem simulations. A satellite motion example containing three subsystems (orbit dynamics, attitude dynamics, and aerodynamics) has been defined and constructed using this approach. Conventional solution methods are used in the subsystem simulations. Distributed and centralized implementations of coupling have been considered. Numerical results are evaluated by direct comparison with a standard total-system, simultaneous-solution approach.

  20. Imagery rescripting as a stand-alone treatment for patients with social phobia: a case series.

    Frets, Petra G; Kevenaar, Ciska; van der Heiden, Colin

    2014-03-01

    The majority of patients with social phobia reports experiencing negative images, usually linked to memories of earlier aversive social experiences. Several studies have indicated that such negative self-imagery appears to have a causal role in maintaining social phobia, which suggests that interventions aimed at dealing with these images could be beneficial in the treatment of social phobia. One potentially powerful approach is imagery rescripting (IR), a clinical intervention that focuses on changing the meaning and impact of unpleasant memories. In the treatment of social phobia IR was only used as part of a broader cognitive-behavioral treatment package. However, we propose that IR alone might also be an effective treatment for this anxiety disorder. The present study reports an initial evaluation of the application of IR as a stand-alone treatment for six adult outpatients presenting with social phobia. A single case series using an A-B replication across patients design was employed. Following a no-treatment baseline period, IR was delivered weekly and patients were followed up for 3 and 6 months. For all patients, substantial reductions were obtained on all outcome measures at post-treatment, and gains were largely maintained at 6-months follow-up. The generalizability of the effects of IR for social phobia is limited by the small number of patients treated by only one therapist. The results of this preliminary case series suggest that IR as a stand alone treatment is an apparently effective intervention in the treatment of patients with social phobia, and indicate that controlled evaluation of its efficacy might be worthwhile. Copyright © 2013 Elsevier Ltd. All rights reserved.

  1. Optimal expansion planning of stand-alone systems with stochastic simulations

    Hoese, Alejandro [Instituto de Energia Electrica (IEE), Universidad Nacional de San Juan, (Argentina)

    1997-12-31

    Stand-alone systems in the range of 1 kW - 10 MW are taking relevance in the new (global) liberal concept of energy market. State and private investors are becoming increasingly attention on the use of renewable for these systems, but it must be shown that these non-conventional solutions are competitive with the established conventional ones. The high investment costs and the technical and economic uncertainties coupled with the use of time-dependent energy sources are the mainly inhibiting factors for the decision agents to choose these systems instead of conventional ones. In the paper a new model for optimal expansion planning of hybrid stand-alone generating systems under consideration of uncertainties is presented. This model is at present in {sup d}evelopment state{sup .} Results already obtained in the first steps of this research are promising and some of them are here presented. [Espanol] Los sistemas autocontenidos en el rango de 1 Kw a 10 MW estan tomando importancia en el nuevo (global) concepto liberal del mercado de la energia. Inversionistas privados y del Estado estan poniendo mayor atencion en el uso de energias renovables para estos sistemas, pero debe mostrarse que estas soluciones no-convencionales son competitivas con las convencionales establecidas. Los altos costos de inversion y las incertidumbres tecnicas y economicas aunadamente con el uso de fuentes de energia dependientes del tiempo son los principales factores inhibidores de los factores de decision para escoger estos sistemas en lugar de los convencionales. En este articulo se presenta un nuevo modelo de planeacion de expansion optima de sistemas hibridos autocontenidos de generacion electrica bajo la consideracion de incertidumbres. Este modelo esta actualmente en {sup e}stado de desarrollo{sup .} Los resultados ya obtenidos en las primeras etapas de esta investigacion son prometedores y se presentan algunos de ellos.

  2. Diagnostic value of the stand-alone synthetic image in digital breast tomosynthesis examinations.

    Garayoa, Julia; Chevalier, Margarita; Castillo, Maria; Mahillo-Fernández, Ignacio; Amallal El Ouahabi, Najim; Estrada, Carmen; Tejerina, Alejandro; Benitez, Olivia; Valverde, Julio

    2018-02-01

    To demonstrate the non-inferiority of synthetic image (SI) mammography versus full-field digital mammography (FFDM) in breast tomosynthesis (DBT) examinations. An observational, retrospective, single-centre, multireader blinded study was performed, using 2384 images to directly compare SI and FFDM based on Breast Imaging Reporting and Data System (BIRADS) categorisation and visibility of radiological findings. Readers had no access to digital breast tomosynthesis slices. Multiple reader, multiple case (MRMC) receiver operating characteristic (ROC) methodology was used to compare the diagnostic performance of SI and FFDM images. The kappa statistic was used to estimate the inter-reader and intra-reader reliability. The area under the ROC curves (AUC) reveals the non-inferiority of SI versus FFDM based on BIRADS categorisation [difference between AUC (ΔAUC), -0.014] and lesion visibility (ΔAUC, -0.001) but the differences were not statistically significant (p=0.282 for BIRADS; p=0.961 for lesion visibility). On average, 77.4% of malignant lesions were detected with SI versus 76.5% with FFDM. Sensitivity and specificity of SI are superior to FFDM for malignant lesions scored as BIRADS 5 and breasts categorised as BIRADS 1. SI is not inferior to FFDM when DBT slices are not available during image reading. SI can replace FFDM, reducing the dose by 45%. • Stand-alone SI demonstrated performance not inferior for lesion visibility as compared to FFDM. • Stand-alone SI demonstrated performance not inferior for lesion BIRADS categorisation as compared to FFDM. • Synthetic images provide important dose savings in breast tomosynthesis examinations.

  3. A Meta-Analytic Review of Stand-Alone Interventions to Improve Body Image.

    Jessica M Alleva

    Full Text Available Numerous stand-alone interventions to improve body image have been developed. The present review used meta-analysis to estimate the effectiveness of such interventions, and to identify the specific change techniques that lead to improvement in body image.The inclusion criteria were that (a the intervention was stand-alone (i.e., solely focused on improving body image, (b a control group was used, (c participants were randomly assigned to conditions, and (d at least one pretest and one posttest measure of body image was taken. Effect sizes were meta-analysed and moderator analyses were conducted. A taxonomy of 48 change techniques used in interventions targeted at body image was developed; all interventions were coded using this taxonomy.The literature search identified 62 tests of interventions (N = 3,846. Interventions produced a small-to-medium improvement in body image (d+ = 0.38, a small-to-medium reduction in beauty ideal internalisation (d+ = -0.37, and a large reduction in social comparison tendencies (d+ = -0.72. However, the effect size for body image was inflated by bias both within and across studies, and was reliable but of small magnitude once corrections for bias were applied. Effect sizes for the other outcomes were no longer reliable once corrections for bias were applied. Several features of the sample, intervention, and methodology moderated intervention effects. Twelve change techniques were associated with improvements in body image, and three techniques were contra-indicated.The findings show that interventions engender only small improvements in body image, and underline the need for large-scale, high-quality trials in this area. The review identifies effective techniques that could be deployed in future interventions.

  4. Optimal expansion planning of stand-alone systems with stochastic simulations

    Hoese, Alejandro [Instituto de Energia Electrica (IEE), Universidad Nacional de San Juan, (Argentina)

    1998-12-31

    Stand-alone systems in the range of 1 kW - 10 MW are taking relevance in the new (global) liberal concept of energy market. State and private investors are becoming increasingly attention on the use of renewable for these systems, but it must be shown that these non-conventional solutions are competitive with the established conventional ones. The high investment costs and the technical and economic uncertainties coupled with the use of time-dependent energy sources are the mainly inhibiting factors for the decision agents to choose these systems instead of conventional ones. In the paper a new model for optimal expansion planning of hybrid stand-alone generating systems under consideration of uncertainties is presented. This model is at present in {sup d}evelopment state{sup .} Results already obtained in the first steps of this research are promising and some of them are here presented. [Espanol] Los sistemas autocontenidos en el rango de 1 Kw a 10 MW estan tomando importancia en el nuevo (global) concepto liberal del mercado de la energia. Inversionistas privados y del Estado estan poniendo mayor atencion en el uso de energias renovables para estos sistemas, pero debe mostrarse que estas soluciones no-convencionales son competitivas con las convencionales establecidas. Los altos costos de inversion y las incertidumbres tecnicas y economicas aunadamente con el uso de fuentes de energia dependientes del tiempo son los principales factores inhibidores de los factores de decision para escoger estos sistemas en lugar de los convencionales. En este articulo se presenta un nuevo modelo de planeacion de expansion optima de sistemas hibridos autocontenidos de generacion electrica bajo la consideracion de incertidumbres. Este modelo esta actualmente en {sup e}stado de desarrollo{sup .} Los resultados ya obtenidos en las primeras etapas de esta investigacion son prometedores y se presentan algunos de ellos.

  5. Factors that can influence the economic feasibility of stand-alone and grid-connected photovoltaic systems: case studies using the software AVES-F

    Blasques, L.C.M.; Pinho, J.T.

    2004-01-01

    This paper presents case studies of economic feasibility of solar photovoltaic systems using the software AVES-F (Analysis of Economic Feasibility of Photovoltaic Systems), developed by the authors, considering cases of stand-alone and grid-connected systems. The software takes into account several factors that can influence the economic feasibility of these kind of systems, like load to be supplied, distance to the grid, the use regime of the system, applied subsidies and others. The main goal of this paper is to analyze some of these factors and to observe how they can affect the economics of PV systems for electricity generation. (authors)

  6. Adaptive Artificial intelligence based fuzzy logic MPPTcontrol for stande-alone photovoltaic system under different atmospheric conditions

    Zaghba Layachi

    2015-08-01

    Full Text Available there is an increased need for analysing the effect of atmospheric variables on photovoltaic (PV production and performance. The outputs from the different PV cells in different atmospheric conditions, such as irradiation and temperature , differ from each other evidencing knowledge deficiency in PV systems [14]. Maximum power point tracking (MPPT methods are used to maximize the PV array output power by tracking continuously the maximum power point (MPP. Among all MPPT methods existing in the literature, perturb and observe (P&O is the most commonly used for its simplicity and ease of implementation; however, it presents drawbacks such as slow response speed, oscillation around the MPP in steady state, and even tracking in wrong way under rapidly changing atmospheric conditions. In order to allow a functioning around the optimal point Mopt, we have inserted a DC-DC converter (Buck–Boost for a better matching between the PV and the load. This paper, we study the Maximum power point tracking using adaptive Intelligent fuzzy logic and conventional (P&O control for stande-alone photovoltaic Array system .In particular, the performances of the controllers are analyzed under variation weather conditions with are constant temperature and variable irradiation. The proposed system is simulated by using MATLAB-SIMULINK. According to the results, fuzzy logic controller has shown better performance during the optimization.

  7. Multi-Objective Optimal Design of Stand-Alone Hybrid Energy System Using Entropy Weight Method Based on HOMER

    Jiaxin Lu

    2017-10-01

    Full Text Available Implementation of hybrid energy system (HES is generally considered as a promising way to satisfy the electrification requirements for remote areas. In the present study, a novel decision making methodology is proposed to identify the best compromise configuration of HES from a set of feasible combinations obtained from HOMER. For this purpose, a multi-objective function, which comprises four crucial and representative indices, is formulated by applying the weighted sum method. The entropy weight method is employed as a quantitative methodology for weighting factors calculation to enhance the objectivity of decision-making. Moreover, the optimal design of a stand-alone PV/wind/battery/diesel HES in Yongxing Island, China, is conducted as a case study to validate the effectiveness of the proposed method. Both the simulation and optimization results indicate that, the optimization method is able to identify the best trade-off configuration among system reliability, economy, practicability and environmental sustainability. Several useful conclusions are given by analyzing the operation of the best configuration.

  8. Key factors for the implementation of successful, stand-alone village electrification schemes in Peru

    Sanchez-Campos, Teodoro

    The hypothesis of this work is that there are social, financial, technical, managerial institutional and political key factors that may either support or prevent the success of small stand alone energy systems in rural areas. This research work aims at contributing to the identification of such factors and study their relevance to the performance and sustainability of stand alone energy systems in rural areas; to meet its purpose, a wide range of literature was reviewed including rural electrification programmes and projects, research and development projects on access to electricity in rural areas, impact studies and others, and a field research survey was done the Andes and Upper Jungle regions in Peru. Nineteen possible critical factors were identified, thirteen with relevance at the local context (the community or village), and six with relevance at the national (or wider) context. From literature review it was found that the possible local critical factors were relevant only to four categories of factors instead of the six considered initially (i.e. social, financial, technological and managerial): the other two categories, political and institutional were found to be more relevant to the national context, therefore those were included in the group of possible critical factors of wider context. A series of questionnaires were designed to collect field data information, which was later used to analyse and establish the relation of each identified factor with the success of the systems studied. The survey research was implemented in 14 villages, 7 with small diesel sets and 7 with small hydropower schemes, all spread in the Andes and Upper Jungle of Peru, which were carefully selected to be representative of regions with isolated stand alone systems and with different socioeconomic background. Out of the 13 possible critical factors of local context, it was found that only 3 are really critical, the others are important but not critical; one of them (technical

  9. Multi-objective analytical model for optimal sizing of stand-alone photovoltaic water pumping systems

    Olcan, Ceyda

    2015-01-01

    Highlights: • An analytical optimal sizing model is proposed for PV water pumping systems. • The objectives are chosen as deficiency of power supply and life-cycle costs. • The crop water requirements are estimated for a citrus tree yard in Antalya. • The optimal tilt angles are calculated for fixed, seasonal and monthly changes. • The sizing results showed the validity of the proposed analytical model. - Abstract: Stand-alone photovoltaic (PV) water pumping systems effectively use solar energy for irrigation purposes in remote areas. However the random variability and unpredictability of solar energy makes difficult the penetration of PV implementations and complicate the system design. An optimal sizing of these systems proves to be essential. This paper recommends a techno-economic optimization model to determine optimally the capacity of the components of PV water pumping system using a water storage tank. The proposed model is developed regarding the reliability and cost indicators, which are the deficiency of power supply probability and life-cycle costs, respectively. The novelty is that the proposed optimization model is analytically defined for two-objectives and it is able to find a compromise solution. The sizing of a stand-alone PV water pumping system comprises a detailed analysis of crop water requirements and optimal tilt angles. Besides the necessity of long solar radiation and temperature time series, the accurate forecasts of water supply needs have to be determined. The calculation of the optimal tilt angle for yearly, seasonally and monthly frequencies results in higher system efficiency. It is, therefore, suggested to change regularly the tilt angle in order to maximize solar energy output. The proposed optimal sizing model incorporates all these improvements and can accomplish a comprehensive optimization of PV water pumping systems. A case study is conducted considering the irrigation of citrus trees yard located in Antalya, Turkey

  10. Five-year durability of stand-alone interspinous process decompression for lumbar spinal stenosis

    Nunley PD

    2017-09-01

    Full Text Available Pierce D Nunley,1 Vikas V Patel,2 Douglas G Orndorff,3 William F Lavelle,4 Jon E Block,5 Fred H Geisler6 1Spine Institute of Louisiana, Shreveport, LA, 2The Spine Center, University of Colorado Hospital, Denver, CO, 3Spine Colorado, Mercy Regional Hospital, Durango, CO, 4Upstate Bone and Joint Center, East Syracuse, NY, 5Independent Consultant, San Francisco, CA, 6Independent Consultant, Chicago, IL, USA Background: Lumbar spinal stenosis is the most common indication for spine surgery in older adults. Interspinous process decompression (IPD using a stand-alone spacer that functions as an extension blocker offers a minimally invasive treatment option for intermittent neurogenic claudication associated with spinal stenosis.Methods: This study evaluated the 5-year clinical outcomes for IPD (Superion® from a randomized controlled US Food and Drug Administration (FDA noninferiority trial. Outcomes included Zurich Claudication Questionnaire (ZCQ symptom severity (ss, physical function (pf, and patient satisfaction (ps subdomains, leg and back pain visual analog scale (VAS, and Oswestry Disability Index (ODI.Results: At 5 years, 84% of patients (74 of 88 demonstrated clinical success on at least two of three ZCQ domains. Individual ZCQ domain success rates were 75% (66 of 88, 81% (71 of 88, and 90% (79 of 88 for ZCQss, ZCQpf, and ZCQps, respectively. Leg and back pain success rates were 80% (68 of 85 and 65% (55 of 85, respectively, and the success rate for ODI was 65% (57 of 88. Percentage improvements over baseline were 42%, 39%, 75%, 66%, and 58% for ZCQss, ZCQpf, leg and back pain VAS, and ODI, respectively (all P<0.001. Within-group effect sizes were classified as very large for four of five clinical outcomes (ie, >1.0; all P<0.0001. Seventy-five percent of IPD patients were free from reoperation, revision, or supplemental fixation at their index level at 5 years.Conclusion: After 5 years of follow-up, IPD with a stand-alone spacer provides

  11. Single anterior cervical discectomy and fusion (ACDF) using self- locking stand-alone polyetheretherketone (PEEK) cage: evaluation of pain and health-related quality of life.

    Kapetanakis, Stylianos; Thomaidis, Tryfon; Charitoudis, George; Pavlidis, Pavlos; Theodosiadis, Panagiotis; Gkasdaris, Grigorios

    2017-09-01

    Anterior cervical discectomy and fusion (ACDF) constitutes the conventional treatment of cervical disc herniation due to degenerative disc disease (DDD). ACDF with plating presents a variety of complications postoperatively and stand-alone cages are thought to be a promising alternative. The aim of this study was firstly, to analyze prospectively collected data from a sample of patients treated with single ACDF using C-Plus self-locking stand-alone PEEK cage system, without the use of plates or screws, in order to evaluate pain levels of patients, utilizing Neck and Arm Pain scale as an expression of visual analogue scale (VAS). Secondly, we aimed to evaluate health-related quality of life, via the short-form 36 (SF-36) and Neck Disability Index (NDI). Thirty-six patients (19 male and 17 female) with mean age 49.6±7 years old who underwent successful single ACDF using self-locking stand-alone PEEK cage for symptomatic cervical DDD were selected for the study. Neck and Arm pain, as well as SF-36 and NDI were estimated preoperatively and 1, 3, 6, and 12 months postoperatively. Patients underwent preoperative and postoperative clinical, neurological and radiological evaluation. The clinical and radiological outcomes were satisfactory after a minimum 1-year follow-up. All results were statistically important (P<0.05), excluding improvement in NDI measured between 6 and 12 months. SF-36, Neck Pain, as well as Arm Pain featured gradual and constant improvement during follow-up, with best scores presenting at 12 months after surgery, while NDI reached its best at 6 months postoperatively. Generally, all scores showed improvement postoperatively during the different phases of the follow-up. Subsequently, ACDF using C-Plus cervical cage constitutes an effective method for cervical disc herniation treatment, in terms of postoperative improvement on pain levels and health-related quality of life and a safe alternative to the conventional method of treatment for cervical DDD.

  12. Segmental kyphosis after cervical interbody fusion with stand-alone polyetheretherketone (PEEK) cages: a comparative study on 2 different PEEK cages.

    Kim, Chi Heon; Chung, Chun Kee; Jahng, Tae-Ahn; Park, Sung Bae; Sohn, Seil; Lee, Sungjoon

    2015-02-01

    Retrospective comparative study. Two polyetheretherketone (PEEK) cages of different designs were compared in terms of the postoperative segmental kyphosis after anterior cervical discectomy and fusion. Segmental kyphosis occasionally occurs after the use of a stand-alone cage for anterior cervical discectomy and fusion. Although PEEK material seems to have less risk of segmental kyphosis compared with other materials, the occurrence of segmental kyphosis for PEEK cages has been reported to be from 0% to 29%. There have been a few reports that addressed the issue of PEEK cage design. A total of 41 consecutive patients who underwent single-level anterior discectomy and fusion with a stand-alone cage were included. Either a round tube-type (Solis; 18 patients, S-group) or a trapezoidal tube-type (MC+; 23 patients, M-group) cage was used. The contact area between the cage and the vertebral body is larger in MC+ than in Solis, and anchoring pins were present in the Solis cage. The effect of the cage type on the segmental angle (SA) (lordosis vs. kyphosis) at postoperative month 24 was analyzed. Preoperatively, segmental lordosis was present in 12/18 S-group and 16/23 M-group patients (P=0.84). The SA was more lordotic than the preoperative angle in both groups just after surgery, with no difference between groups (P=0.39). At 24 months, segmental lordosis was observed in 9/18 S-group and 20/23 M-group patients (P=0.01). The patients in M-group were 7.83 times more likely than patients in S-group (P=0.04; odds ratio, 7.83; 95% confidence interval, 1.09-56.28) not to develop segmental kyphosis. The design of the PEEK cage used may influence the SA, and this association needs to be considered when using stand-alone PEEK cages.

  13. A Comparison of Mindray BC-6800, Sysmex XN-2000, and Beckman Coulter LH750 Automated Hematology Analyzers: A Pediatric Study.

    Ciepiela, Olga; Kotuła, Iwona; Kierat, Szymon; Sieczkowska, Sandra; Podsiadłowska, Anna; Jenczelewska, Anna; Księżarczyk, Karolina; Demkow, Urszula

    2016-11-01

    Modern automated laboratory hematology analyzers allow the measurement of over 30 different hematological parameters useful in the diagnostic and clinical interpretation of patient symptoms. They use different methods to measure the same parameters. Thus, a comparison of complete blood count made by Mindray BC-6800, Sysmex XN-2000 and Beckman Coulter LH750 was performed. A comparison of results obtained by automated analysis of 807 anticoagulated blood samples from children and 125 manual microscopic differentiations were performed. This comparative study included white blood cell count, red blood cell count, and erythrocyte indices, as well as platelet count. The present study showed a poor level of agreement between white blood cell enumeration and differentiation of the three automated hematology analyzers under comparison. A very good agreement was found when comparing manual blood smear and automated granulocytes, monocytes, and lymphocytes differentiation. Red blood cell evaluation showed better agreement than white blood cells between the studied analyzers. To conclude, studied instruments did not ensure satisfactory interchangeability and did not facilitate a substitution of one analyzer by another. © 2016 Wiley Periodicals, Inc.

  14. Efficiency of hydrogen gas production in a stand-alone solar hydrogen system

    Singh, K.; Tamakloe, R.Y.

    2003-01-01

    Many photovoltaic systems operate in a decentralised electricity producing system, or stand-alone mode and the total energy demand is met by the output of the photovoltaic array. The output of the photovoltaic system fluctuates and is unpredictable for many applications making some forms of energy storage system necessary. The role of storage medium is to store the excess energy produced by the photovoltaic arry, to absorb momentary power peaks and to supply energy during sunless periods. One of the storage modes is the use of electrochemical techniques, with batteries and water electrolysis as the most important examples. The present study includes three main parts: the first one is the hydrogen production form the electrolysis of water depending on the DC output current of the photovoltaic (PV) energy source and the charging of the battery. The second part presents the influence of various parameters on the efficiency of hydrogen gas production. The final part includes simulation studies with focus on solar hydrogen efficiency under the influence of various physical and chemical parameters. For a 50W panel-battery-electrolyser system, the dependence of volume of hydrogen gas on voltage, current and power yielded a maximum efficiency of 13.6% (author)

  15. Control of a Stand-Alone Variable Speed Wind Energy Supply System †

    Mohamed M. Hamada

    2013-04-01

    Full Text Available This paper presents a simple control strategy for the operation of a variable speed stand-alone wind turbine with a permanent magnet synchronous generator (PMSG. The PMSG is connected to a three phase resistive load through a switch mode rectifier and a voltage source inverter. Control of the generator side converter is used to achieve maximum power extraction from the available wind power. Control of the DC-DC bidirectional buck-boost converter, which is connected between batteries bank and DC-link voltage, is used to maintain the DC-link voltage at a constant value. It is also used to make the batteries bank stores the surplus of wind energy and supplies this energy to the load during a wind power shortage. The load side voltage source inverter uses a relatively complex vector control scheme to control the output load voltage in terms of amplitude and frequency. The control strategy works under wind speed variation as well as with variable load. Extensive simulation results have been performed using MATLAB/SIMULINK.

  16. Optimal sizing method for constituent elements of stand-alone photovoltaic power systems

    Otsuka, Hirotada; Oi, Yoichi [Hokuriku Electric Power Co., Inc. Toyama (Japan)

    1988-12-25

    The purpose of the report was to calculate the optimal volume of constituent elements of stand-alone photovoltaic power systems, based on the distribution of global radiation on an inclined surface (herein-after called flux of solar radiation), which had been previously measured, and the size of load to be supplied. The least power generation cost was calculated, supposing that setting load was 176kWh/month and the loss of load probability (LOLP) was 1%, by using actual amount of solar radiation in May 1985. The cost was divided into two components: one was proportionate to the size of solar cell, and the other was in proportion to the battery volume. And then, the cost of twenty-year operation(TLC) was calculated. The size of array and the battery volume, which minimize the cost, can be determined when TLC is differentiate. Since auxiliary power source is not attached to this system, it is necessary to restrict the load in order to meet the electric power shortage. In case of the cost at construction in 1984, a standard model indicating the least power generation cost is a photovoltaic system with the array size of A=49.0m{sup 2} and the battery volume of Q=568(Ah). 4 refs., 9 figs., 10 tabs.

  17. Battery Storage Technologies for Electrical Applications: Impact in Stand-Alone Photovoltaic Systems

    Daniel Akinyele

    2017-11-01

    Full Text Available Batteries are promising storage technologies for stationary applications because of their maturity, and the ease with which they are designed and installed compared to other technologies. However, they pose threats to the environment and human health. Several studies have discussed the various battery technologies and applications, but evaluating the environmental impact of batteries in electrical systems remains a gap that requires concerted research efforts. This study first presents an overview of batteries and compares their technical properties such as the cycle life, power and energy densities, efficiencies and the costs. It proposes an optimal battery technology sizing and selection strategy, and then assesses the environmental impact of batteries in a typical renewable energy application by using a stand-alone photovoltaic (PV system as a case study. The greenhouse gas (GHG impact of the batteries is evaluated based on the life cycle emission rate parameter. Results reveal that the battery has a significant impact in the energy system, with a GHG impact of about 36–68% in a 1.5 kW PV system for different locations. The paper discusses new batteries, strategies to minimize battery impact and provides insights into the selection of batteries with improved cycling capacity, higher lifespan and lower cost that can achieve lower environmental impacts for future applications.

  18. [Clinical application of stand-alone MC+PEEK cage in the anterior cervical fusion].

    Jiang, Bing; Cao, Yan-Qing; Pan, Hong; Zhu, Cheng-Run; Zhang, Xiao-Jun; Tao, Yue-Feng; Liu, Zhen

    2015-04-01

    To explore the effect of clinical application of stand-alone MC+PEEK cage in anterior cervical fusion. From January 2011 to January 2014,50 patients were treated with the MC+PEEK cage filled with autogenous cancellous illic-bone graft after anterior cervical discectomy. There were 22 patients with cervical spondylosis,26 patients with traumatic cervical disc herniation, 2 patients with cervical instability in these patients. There were 32 males and 18 females, aged from 30 to 79 years old with an average of 53.30 years old. There were 32 patients with single segment, 15 patients with double segments and 3 patients with three segments. Cervical AP and lateral and the flexion-extension X-rays were regularly taken in order to assess the cervical physiological curvature, the graft fusion and internal fixation related complications. Nerve function, clinical effect and bone fusion were respectively evaluated according to Japan Orthopedic Association (JOA), Otani grade and Suk method. All patients were followed up from 6 to 36 months with an average of 20 months. No correlated surgical complications were found and all patients obtained bony fusion with an average time of 4.30 months. JOA score had significantly improvement after surgery (P cervical fusion can obtain satisfactory clinical effect with less operation injury and reduce the complications. It is a better fusion method in anterior cervical fusion.

  19. Performance and Simulation of a Stand-alone Parabolic Trough Solar Thermal Power Plant

    Mohammad, S. T.; Al-Kayiem, H. H.; Assadi, M. K.; Gilani, S. I. U. H.; Khlief, A. K.

    2018-05-01

    In this paper, a Simulink® Thermolib Model has been established for simulation performance evaluation of Stand-alone Parabolic Trough Solar Thermal Power Plant in Universiti Teknologi PETRONAS, Malaysia. This paper proposes a design of 1.2 kW parabolic trough power plant. The model is capable to predict temperatures at any system outlet in the plant, as well as the power output produced. The conditions that are taken into account as input to the model are: local solar radiation and ambient temperatures, which have been measured during the year. Other parameters that have been input to the model are the collector’s sizes, location in terms of latitude and altitude. Lastly, the results are presented in graphical manner to describe the analysed variations of various outputs of the solar fields obtained, and help to predict the performance of the plant. The developed model allows an initial evaluation of the viability and technical feasibility of any similar solar thermal power plant.

  20. Can aqueous hydrogen peroxide be used as a stand-alone energy source?

    Disselkamp, Robert S.

    2010-01-01

    A novel electrochemical scheme to convert a stand-alone supply of aqueous hydrogen peroxide into a fuel cell-ready stream of hydrogen gas plus aqueous hydrogen peroxide is described. The electrochemical cell, consisting of a solid base and solid acid electrocatalyst, together with a proton exchange membrane, comprise the system that converts aqueous hydrogen peroxide into separate gas streams of oxygen and hydrogen. Aqueous hydrogen peroxide is contained in the anode compartment only and exists in the region where oxygen gas is formed, whereas the cathode compartment is where hydrogen gas is generated and therefore exists in a reduced state. A near zero theoretical over-potential can be achieved by the choice of basicity and acidity of the electrode materials. The primary cost of the electrochemical cell is electrode construction and the aqueous hydrogen peroxide energy storage compound. Additional research effort is required to experimentally validate the concept and explore the full economic impact should initial studies, based on the design presented here, prove promising. (author)

  1. An intelligent stand-alone ultrasonic device for monitoring local structural damage: implementation and preliminary experiments

    Pertsch, Alexander; Kim, Jin-Yeon; Wang, Yang; Jacobs, Laurence J

    2011-01-01

    Continuous structural health monitoring has the potential to significantly improve the safety management of aged, in-service civil structures. In particular, monitoring of local damage growth at hot-spot areas can help to prevent disastrous structural failures. Although ultrasonic nondestructive evaluation (NDE) has proved to be effective in monitoring local damage growth, conventional equipment and devices are usually bulky and only suitable for scheduled human inspections. The objective of this research is to harness the latest developments in embedded hardware and wireless communication for developing a stand-alone, compact ultrasonic device. The device is directed at the continuous structural health monitoring of civil structures. Relying on battery power, the device possesses the functionalities of high-speed actuation, sensing, signal processing, and wireless communication. Integrated with contact ultrasonic transducers, the device can generate 1 MHz Rayleigh surface waves in a steel specimen and measure response waves. An envelope detection algorithm based on the Hilbert transform is presented for efficiently determining the peak values of the response signals, from which small surface cracks are successfully identified

  2. Approaches for developing a sizing method for stand-alone PV systems with variable demand

    Posadillo, R. [Grupo de Investigacion en Energias y Recursos Renovables, Dpto. de Fisica Aplicada, E.P.S., Universidad de Cordoba, Avda. Menendez Pidal s/n, 14004 Cordoba (Spain); Lopez Luque, R. [Grupo de Investigacion de Fisica para las Energias y Recursos Renovables, Dpto. de Fisica Aplicada. Edificio C2 Campus de Rabanales, 14071 Cordoba (Spain)

    2008-05-15

    Accurate sizing is one of the most important aspects to take into consideration when designing a stand-alone photovoltaic system (SAPV). Various methods, which differ in terms of their simplicity or reliability, have been developed for this purpose. Analytical methods, which seek functional relationships between variables of interest to the sizing problem, are one of these approaches. A series of rational considerations are presented in this paper with the aim of shedding light upon the basic principles and results of various sizing methods proposed by different authors. These considerations set the basis for a new analytical method that has been designed for systems with variable monthly energy demands. Following previous approaches, the method proposed is based on the concept of loss of load probability (LLP) - a parameter that is used to characterize system design. The method includes information on the standard deviation of loss of load probability ({sigma}{sub LLP}) and on two new parameters: annual number of system failures (f) and standard deviation of annual number of failures ({sigma}{sub f}). The method proves useful for sizing a PV system in a reliable manner and serves to explain the discrepancies found in the research on systems with LLP<10{sup -2}. We demonstrate that reliability depends not only on the sizing variables and on the distribution function of solar radiation, but on the minimum value as well, which in a given location and with a monthly average clearness index, achieves total solar radiation on the receiver surface. (author)

  3. Stand-alone excitation synchronous wind power generators with power flow management strategy

    Tzuen-Lih Chern

    2014-09-01

    Full Text Available This study presents a stand-alone excitation synchronous wind power generator (SESWPG with power flow management strategy (PFMS. The rotor speed of the excitation synchronous generator tracks the utility grid frequency by using servo motor tracking technologies. The automatic voltage regulator governs the exciting current of generator to achieve the control goals of stable voltage. When wind power is less than the needs of the consumptive loading, the proposed PFMS increases motor torque to provide a positive power output for the loads, while keeping the generator speed constant. Conversely, during the periods of wind power greater than output loads, the redundant power of generator production is charged to the battery pack and the motor speed remains constant with very low power consumption. The advantage of the proposed SESWPG is that the generator can directly output stable alternating current (AC electricity without using additional DC–AC converters. The operation principles with software simulation for the system are described in detail. Experimental results of a laboratory prototype are shown to verify the feasibility of the system.

  4. Analysis and control of induction generator supplying stand-alone AC loads employing a Matrix Converter

    Sumedha Mahajan

    2017-04-01

    Full Text Available This paper proposes a Capacitor Excited Induction Generator (CEIG-Matrix Converter (MC system for feeding stand-alone AC loads. The variable output voltage magnitude and frequency from CEIG is converted into a constant voltage magnitude and frequency at the load terminals by controlling MC using Space Vector Modulation (SVM technique. This single-stage MC is turned up as a good alternative for the proposed system against commonly used AC/DC/AC two stage power converters. The configuration and implementation of the closed-loop control scheme employing dSPACE 1103 real time controller have been fully described in the paper. The proposed closed-loop controller regulates the AC load voltage irrespective of changes in the prime mover speed and load. A method for predetermining the steady-state performance of the proposed system has been developed and described with relevant analytical expressions. The effectiveness of the proposed system is exemplified through simulation results for various operating conditions. The proposed control technique is further validated using an experimental setup developed in the laboratory.

  5. Design of a reliable and low-cost stand-alone micro hydropower station

    Kusakana, K.; Munda, J.L. [Tshwane Univ. of Technology, Pretoria (South Africa)

    2008-07-01

    A stand-alone micro-hydropower station was presented. The plant was comprised of a squirrel cage induction machine coupled to a Kaplan water turbine. Power converters were used to control the variable frequency and voltage outputs of the generator caused by variations in water flow. The hydropower plant was installed a farm in the Kwazulu-Natal region of South Africa, and was designed to provide electricity in relation to the low power demand of users in the region as well as according to the site's hydrology and topology. Load forecasts for the 8 houses using the system were conducted. A generator with a higher output than the average power needed to feed the load was selected in order to ensure load supply during peak demand. The system was designed to shore energy generated during off-peak periods in batteries. An AC-DC-AC converter was used as an interface between the generator and the load in order to ensure voltage and frequency stabilization. Simulations of plant components were conducted to demonstrate output power supply during water flow variations. Results of the modelling study indicated that power converters are needed to stabilize generator outputs. The hydropower design is a cost-effective means of supplying power to low-income households. 10 refs., 2 tabs., 7 figs.

  6. Simulation of stand alone PV system; Dokuritsugata taiyoko hatsuden system no simulation

    Kondo, H; Ogawa, H; Sekii, Y [Chiba Institute of Technology, Chiba (Japan); Tsuda, I; Nozaki, K [Electrotechnical Laboratory, Tsukuba (Japan); Kurokawa, K [Tokyo University of Agriculture and Technology, Tokyo (Japan)

    1996-10-27

    In order to evaluate the simulation results of a photovoltaic power generation system, an operation simulation was carried out using the actual measured data of a stand alone PV system in Miyakojima, Okinawa Prefecture, so as to make a comparison with the actual operation data. The electric power was supplied to 250 houses and primary/junior high schools in the surrounding villages, which had an average demand load of approximately 90kw and the maximum of approximately 200kw. The power was supplied through the PV power generation in the duration of the sunshine, with an excess power charged in storage batteries and then supplied from the batteries at night. The array capacity was made 750kWp, the output current and storage batteries being characteristic type with an actual efficiency curve used for the inverter. The weather data used were the actual inclined insolation quantity and the outside air temperature data for a period of one month of November. The power charged in excess of 100% in the batteries was termed as an overflow power. With the charging condition 30% or less, a diesel generator was run for a rated operation for one hour, the power of which was termed as a backup power. As a result, the simulation was found nearly in agreement with the actual measurements. 5 refs., 7 figs., 2 tabs.

  7. Solar photovoltaic applications seminar: design, installation and operation of small, stand-alone photovoltaic power systems

    1980-07-01

    This seminar material was developed primarily to provide solar photovoltaic (PV) applied engineering technology to the Federal community. An introduction to photoconductivity, semiconductors, and solar photovoltaic cells is included along with a demonstration of specific applications and application identification. The seminar details general systems design and incorporates most known information from industry, academia, and Government concerning small solar cell power system design engineering, presented in a practical and applied manner. Solar PV power system applications involve classical direct electrical energy conversion and electric power system analysis and synthesis. Presentations and examples involve a variety of disciplines including structural analysis, electric power and load analysis, reliability, sizing and optimization; and, installation, operation and maintenance. Four specific system designs are demonstrated: water pumping, domestic uses, navigational and aircraft aids, and telecommunications. All of the applications discussed are for small power requirement (under 2 kilowatts), stand-alone systems to be used in remote locations. Also presented are practical lessons gained from currently installed and operating systems, problems at sites and their resolution, a logical progression through each major phase of system acquisition, as well as thorough design reviews for each application.

  8. Use of Super-Capacitor to Enhance Charging Performance of Stand-Alone Solar PV System

    Huang, B. J.

    2011-01-01

    Introduction: The battery charging performance in a stand-alone solar PV system affects the PV system efficiency and the load operating time. The New Energy Center of National Taiwan University has been devoted to the development of a PWM charging technique to continue charging the lead-acid battery after the overcharge point to increase the battery storage capacity by more than 10%. The present study intends to use the super-capacitor to further increase the charge capacity before the overcharge point of the battery. The super-capacitor is connected in parallel to the lead-acid battery. This will reduce the overall charging impedance during the charge and increase the charging current, especially in sunny weather. A system dynamics model of the lead-acid battery and super-capacitor was derived and the control system simulation was carried out to predict the charging performance for various weathers. It shows that the overall battery impedance decreases and charging power increases with increasing solar radiation. An outdoor comparative test for two identical PV systems with and without supercapacitor was carried out. The use of super-capacitor is shown to be able to increase the lead-acid charging capacity by more than 25% at sunny weather and 10% in cloudy weather. © Springer-Verlag Berlin Heidelberg 2011.

  9. On the economics of stand-alone renewable hybrid power plants in remote regions

    Petrakopoulou, Fontina

    2016-01-01

    Highlights: • Economic evaluation of three renewable hybrid power plants for off-grid operation. • The high electricity cost of remote regions increases the competitiveness of renewable energy. • The proposed plants are economically viable when compared to the existing situation. • The zero direct emissions of the plants constitute an additional advantage of the plants. - Abstract: In recent years ever more examples of regions that have managed to achieve or orientate themselves toward renewable energy sufficiency are emerging. However, actions to create energy autonomy are mainly the result of isolated activities and they are less driven from fully organized movements. In addition, total energy independence without the support of a centralized electrical grid is yet to be achieved. The objectives of this work are to investigate the associated costs of stand-alone renewable hybrid power plants on a Greek island and compare them to the cost of the currently used fossil-fuel-based conventional plant. The plants examined here are designed to fully cover the electricity needs of the island. Islands may face numerous energy problems and rely heavily on foreign and environmentally-harmful fuels. It is shown that the relatively high cost of electricity of such a remote region can increase the competitiveness and promote the wider incorporation of technologies based on renewable energy sources that may, in other cases, seem economically inferior to business-as-usual energy solutions.

  10. MIRNA-DISTILLER: a stand-alone application to compile microRNA data from databases

    Jessica K. Rieger

    2011-07-01

    Full Text Available MicroRNAs (miRNA are small non-coding RNA molecules of ~22 nucleotides which regulate large numbers of genes by binding to seed sequences at the 3’-UTR of target gene transcripts. The target mRNA is then usually degraded or translation is inhibited, although thus resulting in posttranscriptional down regulation of gene expression at the mRNA and/or protein level. Due to the bioinformatic difficulties in predicting functional miRNA binding sites, several publically available databases have been developed that predict miRNA binding sites based on different algorithms. The parallel use of different databases is currently indispensable, but highly uncomfortable and time consuming, especially when working with numerous genes of interest. We have therefore developed a new stand-alone program, termed MIRNA-DISTILLER, which allows to compile miRNA data for given target genes from public databases. Currently implemented are TargetScan, microCosm, and miRDB, which may be queried independently, pairwise, or together to calculate the respective intersections. Data are stored locally for application of further analysis tools including freely definable biological parameter filters, customized output-lists for both miRNAs and target genes, and various graphical facilities. The software, a data example file and a tutorial are freely available at http://www.ikp-stuttgart.de/content/language1/html/10415.asp

  11. MIRNA-DISTILLER: A Stand-Alone Application to Compile microRNA Data from Databases.

    Rieger, Jessica K; Bodan, Denis A; Zanger, Ulrich M

    2011-01-01

    MicroRNAs (miRNA) are small non-coding RNA molecules of ∼22 nucleotides which regulate large numbers of genes by binding to seed sequences at the 3'-untranslated region of target gene transcripts. The target mRNA is then usually degraded or translation is inhibited, although thus resulting in posttranscriptional down regulation of gene expression at the mRNA and/or protein level. Due to the bioinformatic difficulties in predicting functional miRNA binding sites, several publically available databases have been developed that predict miRNA binding sites based on different algorithms. The parallel use of different databases is currently indispensable, but highly uncomfortable and time consuming, especially when working with numerous genes of interest. We have therefore developed a new stand-alone program, termed MIRNA-DISTILLER, which allows to compile miRNA data for given target genes from public databases. Currently implemented are TargetScan, microCosm, and miRDB, which may be queried independently, pairwise, or together to calculate the respective intersections. Data are stored locally for application of further analysis tools including freely definable biological parameter filters, customized output-lists for both miRNAs and target genes, and various graphical facilities. The software, a data example file and a tutorial are freely available at http://www.ikp-stuttgart.de/content/language1/html/10415.asp.

  12. 49 CFR 1109.4 - Mandatory mediation in rate cases to be considered under the stand-alone cost methodology.

    2010-10-01

    ... 49 Transportation 8 2010-10-01 2010-10-01 false Mandatory mediation in rate cases to be considered... § 1109.4 Mandatory mediation in rate cases to be considered under the stand-alone cost methodology. (a) A... methodology must engage in non-binding mediation of its dispute with the railroad upon filing a formal...

  13. An improved synchronous reference frame phase-locked loop for stand-alone variable speed constant frequency power generation systems

    Liu, Yi; Xu, Wei; Ke, Longzhang

    2017-01-01

    The phase-locked loop (PLL) based on conventional synchronous reference frame, i.e. dqPLL, is usually employed in grid-connected variable speed constant frequency (VSCF) power generation systems (PGSs). However, the voltage amplitude drop of stand-alone PGSs is often greater than that of the grid...

  14. Stand-Alone Photovoltaic System Assessment in Warmer Urban Areas in Mexico

    Alberto-Jesus Perea-Moreno

    2018-01-01

    Full Text Available The aim of this study is to examine the possibility of using a stand-alone photovoltaic system (SAPVS for electricity generation in urban areas in Southern Mexico. In Mexico, an urban area is defined as an area where more than 2500 inhabitants live. Due to constant migration from the countryside to the cities, the number of inhabitants of urban localities has been increasing. Global horizontal irradiation (GHI data were recorded every 10 min during 2014–2016 in Coatzacoalcos in the state of Veracruz located on 18°08′09″ N and 94°27′48″ W. In this study, batteries represented 77% of the total cost, 12 PV panels of 310 W could export 5.41 MWh to the grid, and an inverter with an integrated controller and charger was selected, which decreased the initial cost. The city of Coatzacoalcos was chosen because the average annual temperature is 28°, with an average relative humidity of 75% and an average irradiance of 5.3 kWh/m2/day. An emission factor 0.505 tCO2/MWh of greenhouse gases (GHG were obtained, based on the power system, the reduction of net annual GHG would be 11 tCO2 and a financial revenue of 36.951 × 103 $/tCO2 would be obtained. Financial parameters such as a 36.3% Internal Rate Return (IRR and 3.4 years payback show the financial viability of this investment. SAPVSs in urban areas in Mexico could be a benefit as long as housing has a high consumption of electricity.

  15. The Use of Artificial Neural Networks for Forecasting the Electric Demand of Stand-Alone Consumers

    Ivanin, O. A.; Direktor, L. B.

    2018-05-01

    The problem of short-term forecasting of electric power demand of stand-alone consumers (small inhabited localities) situated outside centralized power supply areas is considered. The basic approaches to modeling the electric power demand depending on the forecasting time frame and the problems set, as well as the specific features of such modeling, are described. The advantages and disadvantages of the methods used for the short-term forecast of the electric demand are indicated, and difficulties involved in the solution of the problem are outlined. The basic principles of arranging artificial neural networks are set forth; it is also shown that the proposed method is preferable when the input information necessary for prediction is lacking or incomplete. The selection of the parameters that should be included into the list of the input data for modeling the electric power demand of residential areas using artificial neural networks is validated. The structure of a neural network is proposed for solving the problem of modeling the electric power demand of residential areas. The specific features of generation of the training dataset are outlined. The results of test modeling of daily electric demand curves for some settlements of Kamchatka and Yakutia based on known actual electric demand curves are provided. The reliability of the test modeling has been validated. A high value of the deviation of the modeled curve from the reference curve obtained in one of the four reference calculations is explained. The input data and the predicted power demand curves for the rural settlement of Kuokuiskii Nasleg are provided. The power demand curves were modeled for four characteristic days of the year, and they can be used in the future for designing a power supply system for the settlement. To enhance the accuracy of the method, a series of measures based on specific features of a neural network's functioning are proposed.

  16. Stand-Alone Solar Organic Rankine Cycle Water Pumping System and Its Economic Viability in Nepal

    Suresh Baral

    2015-12-01

    Full Text Available The current study presents the concept of a stand-alone solar organic Rankine cycle (ORC water pumping system for rural Nepalese areas. Experimental results for this technology are presented based on a prototype. The economic viability of the system was assessed based on solar radiation data of different Nepalese geographic locations. The mechanical power produced by the solar ORC is coupled with a water pumping system for various applications, such as drinking and irrigation. The thermal efficiency of the system was found to be 8% with an operating temperature of 120 °C. The hot water produced by the unit has a temperature of 40 °C. Economic assessment was done for 1-kW and 5-kW solar ORC water pumping systems. These systems use different types of solar collectors: a parabolic trough collector (PTC and an evacuated tube collector (ETC. The economic analysis showed that the costs of water are $2.47/m3 (highest and $1.86/m3 (lowest for the 1-kW system and a 150-m pumping head. In addition, the cost of water is reduced when the size of the system is increased and the pumping head is reduced. The minimum volumes of water pumped are 2190 m3 and 11,100 m3 yearly for 1 kW and 5 kW, respectively. The payback period is eight years with a profitability index of 1.6. The system is highly feasible and promising in the context of Nepal.

  17. The eBioKit, a stand-alone educational platform for bioinformatics.

    Hernández-de-Diego, Rafael; de Villiers, Etienne P; Klingström, Tomas; Gourlé, Hadrien; Conesa, Ana; Bongcam-Rudloff, Erik

    2017-09-01

    Bioinformatics skills have become essential for many research areas; however, the availability of qualified researchers is usually lower than the demand and training to increase the number of able bioinformaticians is an important task for the bioinformatics community. When conducting training or hands-on tutorials, the lack of control over the analysis tools and repositories often results in undesirable situations during training, as unavailable online tools or version conflicts may delay, complicate, or even prevent the successful completion of a training event. The eBioKit is a stand-alone educational platform that hosts numerous tools and databases for bioinformatics research and allows training to take place in a controlled environment. A key advantage of the eBioKit over other existing teaching solutions is that all the required software and databases are locally installed on the system, significantly reducing the dependence on the internet. Furthermore, the architecture of the eBioKit has demonstrated itself to be an excellent balance between portability and performance, not only making the eBioKit an exceptional educational tool but also providing small research groups with a platform to incorporate bioinformatics analysis in their research. As a result, the eBioKit has formed an integral part of training and research performed by a wide variety of universities and organizations such as the Pan African Bioinformatics Network (H3ABioNet) as part of the initiative Human Heredity and Health in Africa (H3Africa), the Southern Africa Network for Biosciences (SAnBio) initiative, the Biosciences eastern and central Africa (BecA) hub, and the International Glossina Genome Initiative.

  18. "Candidatus Fokinia solitaria", a Novel "Stand-Alone" Symbiotic Lineage of Midichloriaceae (Rickettsiales.

    Franziska Szokoli

    Full Text Available Recently, the family Midichloriaceae has been described within the bacterial order Rickettsiales. It includes a variety of bacterial endosymbionts detected in different metazoan host species belonging to Placozoa, Cnidaria, Arthropoda and Vertebrata. Representatives of Midichloriaceae are also considered possible etiological agents of certain animal diseases. Midichloriaceae have been found also in protists like ciliates and amoebae. The present work describes a new bacterial endosymbiont, "Candidatus Fokinia solitaria", retrieved from three different strains of a novel Paramecium species isolated from a wastewater treatment plant in Rio de Janeiro (Brazil. Symbionts were characterized through the full-cycle rRNA approach: SSU rRNA gene sequencing and fluorescence in situ hybridization (FISH with three species-specific oligonucleotide probes. In electron micrographs, the tiny rod-shaped endosymbionts (1.2 x 0.25-0.35 μm in size were not surrounded by a symbiontophorous vacuole and were located in the peripheral host cytoplasm, stratified in the host cortex in between the trichocysts or just below them. Frequently, they occurred inside autolysosomes. Phylogenetic analyses of Midichloriaceae apparently show different evolutionary pathways within the family. Some genera, such as "Ca. Midichloria" and "Ca. Lariskella", have been retrieved frequently and independently in different hosts and environmental surveys. On the contrary, others, such as Lyticum, "Ca. Anadelfobacter", "Ca. Defluviella" and the presently described "Ca. Fokinia solitaria", have been found only occasionally and associated to specific host species. These last are the only representatives in their own branches thus far. Present data do not allow to infer whether these genera, which we named "stand-alone lineages", are an indication of poorly sampled organisms, thus underrepresented in GenBank, or represent fast evolving, highly adapted evolutionary lineages.

  19. Stand-Alone Lateral Interbody Fusion for the Treatment of Low-Grade Degenerative Spondylolisthesis

    Luis Marchi

    2012-01-01

    Full Text Available The purpose of this paper was to investigate the stand-alone lateral interbody fusion as a minimally invasive option for the treatment of low-grade degenerative spondylolisthesis with a minimum 24-month followup. Prospective nonrandomized observational single-center study. 52 consecutive patients (67.6±10 y/o; 73.1% female; 27.4±3.4 BMI with single-level grade I/II single-level degenerative spondylolisthesis without significant spine instability were included. Fusion procedures were performed as retroperitoneal lateral transpsoas interbody fusions without screw supplementation. The procedures were performed in average 73.2 minutes and with less than 50cc blood loss. VAS and Oswestry scores showed lasting improvements in clinical outcomes (60% and 54.5% change, resp.. The vertebral slippage was reduced in 90.4% of cases from mean values of 15.1% preoperatively to 7.4% at 6-week followup (P<0.001 and was maintained through 24 months (7.1%, P<0.001. Segmental lordosis (P<0.001 and disc height (P<0.001 were improved in postop evaluations. Cage subsidence occurred in 9/52 cases (17% and 7/52 cases (13% spine levels needed revision surgery. At the 24-month evaluation, solid fusion was observed in 86.5% of the levels treated. The minimally invasive lateral approach has been shown to be a safe and reproducible technique to treat low-grade degenerative spondylolisthesis.

  20. Study on the optimization of stand-alone type photovoltaic systems. 2

    Lee, Man Geun; Song, Jin Soo; Kim, Boo ho; Park, I June; Jung, Meung Woong; Yoo, Kyun Joung; Kim, Hong Woo [Korea Inst. of Energy Research, Taejon (Korea, Republic of)

    1995-12-01

    The objectives of this study are to make a maximization of the operating efficiency of photovoltaic power systems, to improve stand- align PV systems design, technical operation and system analysis, and to promote technical cooperation of mutual interest in the area of IEA/PVPS program. This study aims to investigating the problems of applied photovoltaic power systems currently in operation to improve a system design, seeking remedies of individual PVPS applications to improve the system efficiency and reliability and to raise the system economics, and reporting the international movements of PV system dissemination and technical cooperation for developing countries. For the purpose of this works 1) Investigations of applications of existing photovoltaic power systems: - Photovoltaic electric sources used for expressway lamps - Optimum design of solar light with low pressure sodium lamps under 8 hours lighting a day at night by program-able electronic timer. 2) Comparative analyses of Marado PV system and propose a new reliable PV-diesel hybrid system and high efficiency operations. 3) Overall review of Hahwado 60 KWp PV system extending from 25 KWp and the remote monitoring systems for measurement of its operating results. 4) Introduction of IEA/PVPS international cooperating program, especially in task III for stand- alone PV systems and isolated islands and Exco meeting. As results, investigative findings of PVPS currently in operation and the work for improvement - Propose a prescription of Marado PV systems being blocked up by explosion of electrical demands from residence, parallel operational dual inverter with a big capacity. - There are shortage of solar generated power due to shortage of solar cell capacity that results in an increased operating time of diesel generator. Hence the insolation capacity of solar cell per household is continuously increased from the 0.5 KWp to 2 KWp in Hanwado island electrification.

  1. A Low-Power Wearable Stand-Alone Tongue Drive System for People With Severe Disabilities.

    Jafari, Ali; Buswell, Nathanael; Ghovanloo, Maysam; Mohsenin, Tinoosh

    2018-02-01

    This paper presents a low-power stand-alone tongue drive system (sTDS) used for individuals with severe disabilities to potentially control their environment such as computer, smartphone, and wheelchair using their voluntary tongue movements. A low-power local processor is proposed, which can perform signal processing to convert raw magnetic sensor signals to user-defined commands, on the sTDS wearable headset, rather than sending all raw data out to a PC or smartphone. The proposed sTDS significantly reduces the transmitter power consumption and subsequently increases the battery life. Assuming the sTDS user issues one command every 20 ms, the proposed local processor reduces the data volume that needs to be wirelessly transmitted by a factor of 64, from 9.6 to 0.15 kb/s. The proposed processor consists of three main blocks: serial peripheral interface bus for receiving raw data from magnetic sensors, external magnetic interference attenuation to attenuate external magnetic field from the raw magnetic signal, and a machine learning classifier for command detection. A proof-of-concept prototype sTDS has been implemented with a low-power IGLOO-nano field programmable gate array (FPGA), bluetooth low energy, battery and magnetic sensors on a headset, and tested. At clock frequency of 20 MHz, the processor takes 6.6 s and consumes 27 nJ for detecting a command with a detection accuracy of 96.9%. To further reduce power consumption, an application-specified integrated circuit processor for the sTDS is implemented at the postlayout level in 65-nm CMOS technology with 1-V power supply, and it consumes 0.43 mW, which is 10 lower than FPGA power consumption and occupies an area of only 0.016 mm.

  2. Hydrogen-based energy storage unit for stand alone PV systems

    Labbe, J.

    2006-12-01

    Stand alone systems supplied only by a photovoltaic generator need an energy storage unit to be fully self sufficient. Lead acid batteries are commonly used to store energy because of their low cost, despite several operational constraints. A hydrogen-based energy storage unit (HESU) could be another candidate, including an electrolyser, a fuel cell and a hydrogen tank. However many efforts still need to be carried out for this technology to reach an industrial stage. In particular, market outlets must be clearly identified. The study of small stationary applications (few kW) is performed by numerical simulations. A simulator is developed in the Matlab/Simulink environment. It is mainly composed of a photovoltaic field and a storage unit (lead acid batteries, HESU, or hybrid storage HESU/batteries). The system component sizing is achieved in order to ensure the complete system autonomy over a whole year of operation. The simulator is tested with 160 load profiles (1 kW as a yearly mean value) and three locations (Algeria, France and Norway). Two coefficients are set in order to quantify the correlation between the power consumption of the end user and the renewable resource availability at both daily and yearly scales. Among the tested cases, a limit value of the yearly correlation coefficient came out, enabling to recommend the use of the most adapted storage to a considered case. There are cases for which using HESU instead of lead acid batteries can increase the system efficiency, decrease the size of the photovoltaic field and improve the exploitation of the renewable resource. In addition, hybridization of HESU with batteries always leads to system enhancements regarding its sizing and performance, with an efficiency increase by 10 to 40 % depending on the considered location. The good agreement between the simulation data and field data gathered on real systems enabled the validation of the models used in this study. (author)

  3. Probabilistic modelling and analysis of stand-alone hybrid power systems

    Lujano-Rojas, Juan M.; Dufo-López, Rodolfo; Bernal-Agustín, José L.

    2013-01-01

    As a part of the Hybrid Intelligent Algorithm, a model based on an ANN (artificial neural network) has been proposed in this paper to represent hybrid system behaviour considering the uncertainty related to wind speed and solar radiation, battery bank lifetime, and fuel prices. The Hybrid Intelligent Algorithm suggests a combination of probabilistic analysis based on a Monte Carlo simulation approach and artificial neural network training embedded in a genetic algorithm optimisation model. The installation of a typical hybrid system was analysed. Probabilistic analysis was used to generate an input–output dataset of 519 samples that was later used to train the ANNs to reduce the computational effort required. The generalisation ability of the ANNs was measured in terms of RMSE (Root Mean Square Error), MBE (Mean Bias Error), MAE (Mean Absolute Error), and R-squared estimators using another data group of 200 samples. The results obtained from the estimation of the expected energy not supplied, the probability of a determined reliability level, and the estimation of expected value of net present cost show that the presented model is able to represent the main characteristics of a typical hybrid power system under uncertain operating conditions. - Highlights: • This paper presents a probabilistic model for stand-alone hybrid power system. • The model considers the main sources of uncertainty related to renewable resources. • The Hybrid Intelligent Algorithm has been applied to represent hybrid system behaviour. • The installation of a typical hybrid system was analysed. • The results obtained from the study case validate the presented model

  4. Stand alone solution for generation and storage of hydrogen and electric energy

    Gany, Alon; Elitzur, Shani; Valery

    2015-01-01

    A novel method enabling safe, simple, and controllable production, storage, and use of hydrogen as well as compact electric energy storage and generation via hydrogen- oxygen fuel cells has been developed. The technology indicates, in our opinion, a significant milestone in the search for practical utilization of hydrogen as an alternative energy source. It consists of an original thermal-chemical treatment / activation of aluminum powders to react spontaneously with water to produce hydrogen at regular conditions according to the reaction Al+3H 2 O=Al (OH) 3 +3/2H 2 . Only about 1-2% of lithium, based activator is applied, and any type of water including tap water, sea water and waste water may be used, making the method attractive for variety of applications. 11% of hydrogen compared to the aluminum mass can be obtained, and our experiments reveal 90% reaction yield and more. The technology has a clear advantage over batteries, providing specific electric energy of over 2 kW h/kg Al, 5-10 times greater than that of commonly used lithium-ion batteries. Combined with a fuel cell it may be particularly beneficial for stand-alone electric power generators, where there is no access to the grid. Such applications include emergency generators (e.g., in hospitals), electricity backup systems, and power generation in remote communication posts. Automotive applications may be considered as well. The technology provides green electric energy and quiet operation as well as additional heat energy resulting mainly from the exothermic aluminum-water reaction. (full text)

  5. Energetic and financial investigation of a stand-alone solar-thermal Organic Rankine Cycle power plant

    Tzivanidis, Christos; Bellos, Evangelos; Antonopoulos, Kimon A.

    2016-01-01

    Highlights: • A stand-alone solar driven Organic Rankine Cycle is optimized parametrically. • The system is optimized energetically and financially. • Nine working fluids are tested with cyclohexane to be the most suitable. • A collecting area of 25,000 m"2 parabolic trough collectors is the optimum solution. • The maximum IRR is 13.46% and the payback period is about 9 years. - Abstract: The use of solar thermal energy for electricity production is a clean and sustainable way to cover the increasing energy needs of our society. The most mature technology for capturing solar energy in high temperature levels is the parabolic trough collectors (PTC). In this study, an Organic Rankine Cycle (ORC) coupled with PTC is analyzed parametrically in order to be optimized financially and energetically. The first step is the thermodynamic investigation of the ORC by using various working fluids. The second step is the energetic and financial investigation of the total system which includes the solar field, the storage tank and the ORC module. By testing many combinations of collecting areas and storage tank volumes, finally cyclohexane proved to be the most suitable working fluid for producing 1 MW_e_l with PTC. Specifically, in the optimum situation a solar field of 25,000 m"2 with storage tank of about 300 m"3 leads to a payback period of 9 years and to an internal rate of return (IRR) equal to 13.46%. Moreover, an economic comparison for different commercial collectors is presented, with Eurotrough ET-150 being the financially optimum solution for this case study.

  6. Objective evaluation of analyzer performance based on a retrospective meta-analysis of instrument validation studies: point-of-care hematology analyzers.

    Cook, Andrea M; Moritz, Andreas; Freeman, Kathleen P; Bauer, Natali

    2017-06-01

    Information on quality requirements and objective evaluation of performance of veterinary point-of-care analyzers (POCAs) is scarce. The study was aimed at assessing observed total errors (TE obs s) for veterinary hematology POCAs via meta-analysis and comparing TE obs to allowable total error (TE a ) specifications based on experts' opinions. The TE obs for POCAs (impedance and laser-based) was calculated based on data from instrument validation studies published between 2006 and 2013 as follows: TE obs = 2 × CV [%] + bias [%]. The CV was taken from published studies; the bias was estimated from the regression equation at 2 different concentration levels of measurands. To fulfill quality requirements, TE obs should be 60% of analyzers showed TE obs hematology variables, respectively. For the CBC, TE obs was TE a (data from 3 analyzers). This meta-analysis is considered a pilot study. Experts' requirements (TE obs < TE a ) were fulfilled for most measurands except HGB (due to instrument-related bias for the ADVIA 2120) and platelet counts. Available data on the WBC differential count suggest an analytic bias, so nonstatistical quality control is recommended. © 2017 American Society for Veterinary Clinical Pathology.

  7. Stand-alone flat-plate photovoltaic power systems: System sizing and life-cycle costing methodology for Federal agencies

    Borden, C. S.; Volkmer, K.; Cochrane, E. H.; Lawson, A. C.

    1984-01-01

    A simple methodology to estimate photovoltaic system size and life-cycle costs in stand-alone applications is presented. It is designed to assist engineers at Government agencies in determining the feasibility of using small stand-alone photovoltaic systems to supply ac or dc power to the load. Photovoltaic system design considerations are presented as well as the equations for sizing the flat-plate array and the battery storage to meet the required load. Cost effectiveness of a candidate photovoltaic system is based on comparison with the life-cycle cost of alternative systems. Examples of alternative systems addressed are batteries, diesel generators, the utility grid, and other renewable energy systems.

  8. prfectBLAST: a platform-independent portable front end for the command terminal BLAST+ stand-alone suite.

    Santiago-Sotelo, Perfecto; Ramirez-Prado, Jorge Humberto

    2012-11-01

    prfectBLAST is a multiplatform graphical user interface (GUI) for the stand-alone BLAST+ suite of applications. It allows researchers to do nucleotide or amino acid sequence similarity searches against public (or user-customized) databases that are locally stored. It does not require any dependencies or installation and can be used from a portable flash drive. prfectBLAST is implemented in Java version 6 (SUN) and runs on all platforms that support Java and for which National Center for Biotechnology Information has made available stand-alone BLAST executables, including MS Windows, Mac OS X, and Linux. It is free and open source software, made available under the GNU General Public License version 3 (GPLv3) and can be downloaded at www.cicy.mx/sitios/jramirez or http://code.google.com/p/prfectblast/.

  9. Modeling, design and analysis of a stand-alone hybrid power generation system using solar/urine

    Wu, Wei; Zhou, Ya-Yan; Lin, Mu-Hsuan; Hwang, Jenn-Jiang

    2013-01-01

    Highlights: • The stand-alone hybrid power system is presented. • The urine-to-hydrogen processor is proposed. • Scenario analysis of the hybrid power dispatching and the urine/solar demands is investigated. • The design, modeling and optimization of the hybrid power system is addressed by Aspen Plus and Matlab. - Abstract: The urine turned to hydrogen as an energy conversion process is integrated into a stand-alone hybrid (PV/FC/battery) power generation system. The optimization and simulation of a new urine-to-hydrogen processor is evaluated in Aspen Plus environment. In our approach, the PV generator aims to reduce urine consumption and the lithium-ion battery can compensate the power gap due to the fuel processing delay. Based on prescribed patterns of solar irradiation and the daily load demand of a 30-persons classroom, scenario analyses of the hybrid power dispatching and operational feasibility is addressed

  10. Enhancement of a stand-alone photovoltaic system's performance: Reduction of soft and hard shading

    Lamont, Lisa A.; El Chaar, Lana [Petroleum Institute, Electrical Engineering Department, P.O. Box 2533, Abu Dhabi (United Arab Emirates)

    2011-04-15

    A stand-alone photovoltaic (PV) system is the most promising solution to supply electric power to meet energy demand in isolated locations. This technology can offer an interesting alternative to other currently existing sources of energy. Due to space constraint in the remote offshore oil and gas industry, a stand-alone system is used for cathodic protection, telemetry and valve control. However in such an environment, dust accumulation and bird droppings have been critical issues to the operation of off-grid solar devices. These factors do not only reduce the available power of the modules but also makes the cost of solar devices ineffective since cleaning, especially on well-head towers, is very expensive due to the location. Hence this paper presents two technical solutions that have shown promising results in reducing the impact of these factors. (author)

  11. A review of three stand-alone topical thrombins for surgical hemostasis.

    Cheng, Christine M; Meyer-Massetti, Carla; Kayser, Steven R

    2009-01-01

    Topical thrombins are active hemostatic agents that can be used to minimize blood loss during surgery. Before 2007, the only topical thrombins available were derived from bovine plasma. Antibody formation to bovine thrombin and/or factor V, with subsequent risk of cross-reactivity with human factor V, and hemorrhagic complications associated with human factor-V deficiencies have been described in case reports of surgeries in which bovine thrombins were used. This risk is now included in the boxed warning section of the bovine thrombin prescribing information. In 2007 and 2008, 2 new topical thrombins from nonbovine sources received approval for use from the US Food and Drug Administration. The 3 active topical thrombins that are currently marketed are bovine plasma-derived thrombin, human plasma-derived thrombin, and human recombinant thrombin. The purpose of this review was to evaluate the literature on the efficacy and safety of topical thrombins and discuss the pharmacoeconomic considerations associated with their use. PubMed, EMBASE, and International Pharmaceutical Abstracts were searched for relevant papers published in English through October 10,2008, using the terms thrombin, human recombinant thrombin, bovine thrombin, plasma derived thrombin, and topical thrombin. Manufacturer-provided materials were also reviewed. Abstracts and unpublished data, as well as evaluations of sealants, adhesives, glues, and other hemostats that contain thrombin mixed with fibrinogen and other clotting factors, were excluded. Four randomized, double-blind studies involving the active, stand-alone topical thrombins were found. The bovine thrombin involved in these studies was the predecessor to the currently marketed, highly purified bovine formulation. No studies comparing the human products, studies involving the highly purified bovine preparation, or placebo-controlled studies involving bovine thrombin were found. In a Phase III comparison of human recombinant thrombin and

  12. Control strategy of wind turbine based on permanent magnet synchronous generator and energy storage for stand-alone systems

    Deng, Fujin; Liu, Dong; Chen, Zhe

    2017-01-01

    This paper investigates a variable speed wind turbine based on permanent magnet synchronous generator and a full-scale power converter in a stand-alone system. An energy storage system(ESS) including battery and fuel cell-electrolyzer combination is connected to the DC link of the full-scale power...... converter through the power electronics interface. Wind is the primary power source of the system, the battery and FC-electrolyzer combination is used as a backup and a long-term storage system to provide or absorb power in the stand-alone system, respectively. In this paper, a control strategy is proposed...... for the operation of this variable speed wind turbine in a stand-alone system, where the generator-side converter and the ESS operate together to meet the demand of the loads. This control strategy is competent for supporting the variation of the loads or wind speed and limiting the DC-link voltage of the full...

  13. Sizing, techno-economic and generation management analysis of a stand alone photovoltaic power unit including storage devices

    Jallouli, Rihab; Krichen, Lotfi

    2012-01-01

    Due to the mismatch between the load demand and the intermittent solar energy, a stand-alone photovoltaic-hydrogen system and an optimal control scheme are designed to maintain the high system efficiency. Based on meteorological and the load demand data, a system sizing technique is proposed to establish the minimum capacity of the system components, which are a photovoltaic (PV) panel, a proton exchange membrane fuel cell (PEMFC), a battery bank and an alkaline electrolyzer (Elz). An accurate energy management scheme that is utilized during power transfer is proposed to meet the economic requirements. Case studies are used to verify the efficiency of the energy management strategy and system sizing technique. Simulation results illustrate a simple solution to the design and processing of stand-alone PV-hydrogen (PV-H 2 ) systems. -- Highlights: ► We study a stand alone PV-hydrogen system comprising renewable devices. ► A PV generator, a battery bank, a fuel cell and an electrolyzer are modeled. ► Power management taking into account the economic arrangement and the operating conditions to ensure energy availability is proposed.

  14. Optimum autonomous stand-alone photovoltaic system design on the basis of energy pay-back analysis

    Kaldellis, J.K.; Zafirakis, D.; Kondili, E.

    2009-01-01

    Stand-alone photovoltaic (PV) systems comprise one of the most promising electrification solutions for covering the demand of remote consumers. However, such systems are strongly questioned due to extreme life-cycle (LC) energy requirements. For similar installations to be considered as environmentally sustainable, their LC energy content must be compensated by the respective useful energy production, i.e. their energy pay-back period (EPBP) should be found less than their service period. In this context, an optimum sizing methodology is currently developed, based on the criterion of minimum embodied energy. Various energy autonomous stand-alone PV-lead-acid battery systems are examined and two different cases are investigated; a high solar potential area and a medium solar potential area. By considering that the PV-battery (PV-Bat) system's useful energy production is equal to the remote consumer's electricity consumption, optimum cadmium telluride (CdTe) based systems yield the minimum EPBP (15 years). If achieving to exploit the net PV energy production however, the EPBP is found less than 20 years for all PV types. Finally, the most interesting finding concerns the fact that in all cases examined the contribution of the battery component exceeds 27% of the system LC energy requirements, reflecting the difference between grid-connected and stand-alone configurations.

  15. A New Vector Control of Brushless Doubly-Fed Inductor Generator With Transient Current Compensation for Stand-Alone Power Generation Applications

    Liu, Yi; Xu, Wei; Yu, Kailiang

    2018-01-01

    The stand-alone brushless doubly-fed induction generator (BDFIG) with the conventional control strategies suffers heavily from poor dynamic performance especially under heavy load disturbance. This paper presents a new vector control strategy of BDFIG for stand-alone power generation applications...... control strategies, and the results verify the satisfactory dynamic performance of the proposed strategy....

  16. New control strategy of stand-alone brushless doubly-fed induction generator for supplying unbalanced loads in ship shaft power generation system

    Liu, Yi; Xu, Wei; Xiong, Fei

    2017-01-01

    The ship shaft power generation system based on a stand-alone brushless doubly-fed induction generator (BDFIG) have demonstrated excellent saving-energy performance. This paper presents a new control scheme of the stand-alone BDFIG for supplying unbalanced loads in the ship shaft power generation...

  17. Evaluation of the URIT-2900 automated hematology analyzer for screening of thalassemia and hemoglobinopathies in Southeast Asian populations.

    Karnpean, Rossarin; Pansuwan, Anupong; Fucharoen, Goonnapa; Fucharoen, Supan

    2011-07-01

    The effectiveness of the URIT-2900 Hematology Analyzer for screening of hemoglobinopathies commonly found in Southeast Asian populations was examined. Appropriate cut-off values of MCV and MCH for screening of α(0) and β thalassemias were derived from the receiver operator characteristic curve conducted initially on 279 subjects with various thalassemia genotypes. Validation was performed additionally in a cohort of another unrelated 313 subjects. The best cut off values of MCV and MCH were found to be 78fL and 27pg, respectively. Using these cut off values in combination with the dichlorophenolindophenol test in screening of α(0) thalassemia, β thalassemia and Hb E in a cohort study revealed 100% sensitivity, 79.6% specificity, 80.0% positive predictive value and 100% negative predictive value. The combined blood cell counting using the URIT-2900 Automated Hematology Analyzer and dichlorophenolindophenol test is suitable for population screening of thalassemia and hemoglobinopathies in Southeast Asia. Copyright © 2011 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

  18. Methanol production via pressurized entrained flow biomass gasification – Techno-economic comparison of integrated vs. stand-alone production

    Andersson, Jim; Lundgren, Joakim; Marklund, Magnus

    2014-01-01

    The main objective with this work was to investigate techno-economically the opportunity for integrated gasification-based biomass-to-methanol production in an existing chemical pulp and paper mill. Three different system configurations using the pressurized entrained flow biomass gasification (PEBG) technology were studied, one stand-alone plant, one where the bark boiler in the mill was replaced by a PEBG unit and one with a co-integration of a black liquor gasifier operated in parallel with a PEBG unit. The cases were analysed in terms of overall energy efficiency (calculated as electricity-equivalents) and process economics. The economics was assessed under the current as well as possible future energy market conditions. An economic policy support was found to be necessary to make the methanol production competitive under all market scenarios. In a future energy market, integrating a PEBG unit to replace the bark boiler was the most beneficial case from an economic point of view. In this case the methanol production cost was reduced in the range of 11–18 Euro per MWh compared to the stand-alone case. The overall plant efficiency increased approximately 7%-units compared to the original operation of the mill and the non-integrated stand-alone case. In the case with co-integration of the two parallel gasifiers, an equal increase of the system efficiency was achieved, but the economic benefit was not as apparent. Under similar conditions as the current market and when methanol was sold to replace fossil gasoline, co-integration of the two parallel gasifiers was the best alternative based on received IRR. - Highlights: • Techno-economic results regarding integration of methanol synthesis processes in a pulp and paper mill are presented. • The overall energy efficiency increases in integrated methanol production systems compared to stand-alone production units. • The economics of the integrated system improves compared to stand-alone alternatives. • Tax

  19. Maintenance of Segmental Lordosis and Disk Height in Stand-alone and Instrumented Extreme Lateral Interbody Fusion (XLIF).

    Malham, Gregory M; Ellis, Ngaire J; Parker, Rhiannon M; Blecher, Carl M; White, Rohan; Goss, Ben; Seex, Kevin A

    2017-03-01

    A prospective single-surgeon nonrandomized clinical study. To evaluate the radiographic and clinical outcomes, by fixation type, in extreme lateral interbody fusion (XLIF) patients and provide an algorithm for determining patients suitable for stand-alone XLIF. XLIF may be supplemented with pedicle screw fixation, however, since stabilizing structures remain intact, it is suggested that stand-alone XLIF can be used for certain indications. This eliminates the associated morbidity, though subsidence rates may be elevated, potentially minimizing the clinical benefits. A fixation algorithm was developed after evaluation of patient outcomes from the surgeon's first 30 cases. This algorithm was used prospectively for 40 subsequent patients to determine the requirement for supplemental fixation. Preoperative, postoperative, and 12-month follow-up computed tomography scans were measured for segmental and global lumbar lordosis and posterior disk height. Clinical outcome measures included back and leg pain (visual analogue scale), Oswestry Disability Index (ODI), and SF-36 physical and mental component scores (PCS and MCS). Preoperatively to 12-month follow-up there were increases in segmental lordosis (7.9-9.4 degrees, P=0.0497), lumbar lordosis (48.8-55.2 degrees, P=0.0328), and disk height (3.7-5.5 mm, P=0.0018); there were also improvements in back (58.6%) and leg pain (60.0%), ODI (44.4%), PCS (56.7%), and MCS (16.1%) for stand-alone XLIF. For instrumented XLIF, segmental lordosis (7.6-10.5 degrees, P=0.0120) and disk height (3.5-5.6 mm, Plordosis decreased (51.1-45.8 degrees, P=0.2560). Back (49.8%) and leg pain (30.8%), ODI (32.3%), PCS (37.4%), and MCS (2.0%) were all improved. Subsidence occurred in 3 (7.5%) stand-alone patients. The XLIF treatment fixation algorithm provided a clinical pathway to select suitable patients for stand-alone XLIF. These patients achieved positive clinical outcomes, satisfactory fusion rates, with sustained correction of lordosis and

  20. Stand-Alone Personalized Normative Feedback for College Student Drinkers: A Meta-Analytic Review, 2004 to 2014.

    Keri B Dotson

    Full Text Available Norms clarification has been identified as an effective component of college student drinking interventions, prompting research on norms clarification as a single-component intervention known as Personalized Normative Feedback (PNF. Previous reviews have examined PNF in combination with other components but not as a stand-alone intervention.To investigate the degree to which computer-delivered stand-alone personalized normative feedback interventions reduce alcohol consumption and alcohol-related harms among college students and to compare gender-neutral and gender-specific PNF.Electronic databases were searched systematically through November 2014. Reference lists were reviewed manually and forward and backward searches were conducted.Outcome studies that compared computer-delivered, stand-alone PNF intervention with an assessment only, attention-matched, or active treatment control and reported alcohol use and harms among college students.Between-group effect sizes were calculated as the standardized mean difference in change scores between treatment and control groups divided by pooled standard deviation. Within-group effect sizes were calculated as the raw mean difference between baseline and follow-up divided by pooled within-groups standard deviation.Eight studies (13 interventions with a total of 2,050 participants were included. Compared to control participants, students who received gender-neutral (dbetween = 0.291, 95% CI [0.159, 0.423] and gender-specific PNF (dbetween = 0.284, 95% CI [0.117, 0.451] reported greater reductions in drinking from baseline to follow-up. Students who received gender-neutral PNF reported 3.027 (95% CI [2.171, 3.882] fewer drinks per week at first follow-up and gender-specific PNF reported 3.089 (95% CI [0.992, 5.186] fewer drinks. Intervention effects were small for harms (dbetween = 0.157, 95% CI [0.037, 0.278].Computer-delivered PNF is an effective stand-alone approach for reducing college student

  1. Stand-Alone Personalized Normative Feedback for College Student Drinkers: A Meta-Analytic Review, 2004 to 2014.

    Dotson, Keri B; Dunn, Michael E; Bowers, Clint A

    2015-01-01

    Norms clarification has been identified as an effective component of college student drinking interventions, prompting research on norms clarification as a single-component intervention known as Personalized Normative Feedback (PNF). Previous reviews have examined PNF in combination with other components but not as a stand-alone intervention. To investigate the degree to which computer-delivered stand-alone personalized normative feedback interventions reduce alcohol consumption and alcohol-related harms among college students and to compare gender-neutral and gender-specific PNF. Electronic databases were searched systematically through November 2014. Reference lists were reviewed manually and forward and backward searches were conducted. Outcome studies that compared computer-delivered, stand-alone PNF intervention with an assessment only, attention-matched, or active treatment control and reported alcohol use and harms among college students. Between-group effect sizes were calculated as the standardized mean difference in change scores between treatment and control groups divided by pooled standard deviation. Within-group effect sizes were calculated as the raw mean difference between baseline and follow-up divided by pooled within-groups standard deviation. Eight studies (13 interventions) with a total of 2,050 participants were included. Compared to control participants, students who received gender-neutral (dbetween = 0.291, 95% CI [0.159, 0.423]) and gender-specific PNF (dbetween = 0.284, 95% CI [0.117, 0.451]) reported greater reductions in drinking from baseline to follow-up. Students who received gender-neutral PNF reported 3.027 (95% CI [2.171, 3.882]) fewer drinks per week at first follow-up and gender-specific PNF reported 3.089 (95% CI [0.992, 5.186]) fewer drinks. Intervention effects were small for harms (dbetween = 0.157, 95% CI [0.037, 0.278]). Computer-delivered PNF is an effective stand-alone approach for reducing college student drinking and

  2. Grid parity analysis of stand-alone hybrid microgrids: A comparative study of Germany, Pakistan, South Africa and the United States

    Siddiqui, Jawad M.

    Grid parity for alternative energy resources occurs when the cost of electricity generated from the source is lower than or equal to the purchasing price of power from the electricity grid. This thesis aims to quantitatively analyze the evolution of hybrid stand-alone microgrids in the US, Germany, Pakistan and South Africa to determine grid parity for a solar PV/Diesel/Battery hybrid system. The Energy System Model (ESM) and NREL's Hybrid Optimization of Multiple Energy Resources (HOMER) software are used to simulate the microgrid operation and determine a Levelized Cost of Electricity (LCOE) figure for each location. This cost per kWh is then compared with two distinct estimates of future retail electricity prices at each location to determine grid parity points. Analysis results reveal that future estimates of LCOE for such hybrid stand-alone microgrids range within the 35-55 cents/kWh over the 25 year study period. Grid parity occurs earlier in locations with higher power prices or unreliable grids. For Pakistan grid parity is already here, while Germany hits parity between the years 2023-2029. Results for South Africa suggest a parity time range of the years 2040-2045. In the US, places with low grid prices do not hit parity during the study period. Sensitivity analysis results reveal the significant impact of financing and the cost of capital on these grid parity points, particularly in developing markets of Pakistan and South Africa. Overall, the study helps conclude that variations in energy markets may determine the fate of emerging energy technologies like microgrids. However, policy interventions have a significant impact on the final outcome, such as the grid parity in this case. Measures such as eliminating uncertainty in policies and improving financing can help these grids overcome barriers in developing economies, where they may find a greater use much earlier in time.

  3. An optimized Fuzzy Logic Controller by Water Cycle Algorithm for power management of Stand-alone Hybrid Green Power generation

    Sarvi, Mohammad; Avanaki, Isa Nasiri

    2015-01-01

    Highlights: • A new method to improve the performance of renewable power management is proposed. • The proposed method is based on Fuzzy Logic optimized by the Water Cycle Algorithm. • The proposed method characteristics are compared with two other methods. • The comparisons confirm that the proposed method is robust and effectiveness one. - Abstract: This paper aims to improve the power management system of a Stand-alone Hybrid Green Power generation based on the Fuzzy Logic Controller optimized by the Water Cycle Algorithm. The proposed Stand-alone Hybrid Green Power consists of wind energy conversion and photovoltaic systems as primary power sources and a battery, fuel cell, and Electrolyzer as energy storage systems. Hydrogen is produced from surplus power generated by the wind energy conversion and photovoltaic systems of Stand-alone Hybrid Green Power and stored in the hydrogen storage tank for fuel cell later using when the power generated by primary sources is lower than load demand. The proposed optimized Fuzzy Logic Controller based power management system determines the power that is generated by fuel cell or use by Electrolyzer. In a hybrid system, operation and maintenance cost and reliability of the system are the important issues that should be considered in studies. In this regard, Water Cycle Algorithm is used to optimize membership functions in order to simultaneously minimize the Loss of Power Supply Probability and operation and maintenance. The results are compared with the particle swarm optimization and the un-optimized Fuzzy Logic Controller power management system to prove that the proposed method is robust and effective. Reduction in Loss of Power Supply Probability and operation and maintenance, are the most advantages of the proposed method. Moreover the level of the State of Charge of the battery in the proposed method is higher than other mentioned methods which leads to increase battery lifetime.

  4. Hierarchical energy management system for stand-alone hybrid system based on generation costs and cascade control

    Torreglosa, J.P.; García, P.; Fernández, L.M.; Jurado, F.

    2014-01-01

    Highlights: • We present an energy management system for a stand-alone WT/PV/hydrogen/battery hybrid system. • Hierarchical control composed by master and slave control strategies. • Control assures reliable electricity support for stand-alone applications subject to technical and economic criteria. - Abstract: This paper presents an energy management system (EMS) for stand-alone hybrid systems composed by photovoltaic (PV) solar panels and a wind turbine (WT) as primary energy sources and two energy storage systems, which are a hydrogen system and a battery. The hydrogen system is composed of fuel cell (FC), electrolyzer and hydrogen storage tank. The EMS is a hierarchical control composed by a master control strategy and a slave control strategy. On the one hand, the master control generates the reference powers to meet several premises (such as to satisfy the load power demand, and to maintain the hydrogen tank level and the state of charge (SOC) of the battery between their target margins), taking also into account economic aspects to discriminate between using the battery or hydrogen system. On the other hand, the slave control modifies the reference powers generated by the master control according to the energy sources dynamic limitations, and maintains the DC bus voltage at its reference value. The models, implemented in MATLAB-Simulink environment, have been developed from commercially available components. To check the viability of the proposed EMS, two kinds of simulations were carried out: (1) A long-term simulation of 25 years (expected lifetime of the system) with a sample time of one hour to validate the master control of the EMS; and (2) A short-term simulation with sudden net power variations to validate the slave control of the EMS

  5. Efficiency of the hybrid solar-wind systems for electricity supply to the stand-alone sites

    Abdullaev, D.A.; Isaev, R.I.

    2000-01-01

    The features of stand-alone sites and principles of their electricity supply is described there is going observation of the works about conditions of production and efficiency of using autonomy wind turbines and photovoltaics. Their unsufficiency is estimated. The advantages of hybrid systems and their realization schemes is described. The advantage of hybrid solar-wind Battery system (HSWBS) on the basis of own researches and the facts of other authors are given. The conception overall discounting cost is developed on HSWBS case. (Author)

  6. Evaluation of a proper controller performance for maximum-power point tracking of a stand-alone PV system

    Nafeh, A.E.-S.A.; Fahmy, F.H. [Electronics Research Institute, Cairo (Egypt); El-Zahab, E.M.A. [Cairo University, Giza (Egypt). Faculty of Engineering

    2003-02-01

    In this paper the implementation of a suggested stand-alone PV system, for maximum-power point tracking (MPPT), is carried out. Also, this paper presents a comparative study, through experimental work, between the conventional PI controller and the fuzzy logic controller (FLC) under different atmospheric conditions. The implemented system with both the PI controller and the FLC gives a good maximum-power operation of the PV array, but the tracking capability for different optimum operating points is better and faster for the case of using the FLC compared to the case of using the PI controller. (author)

  7. EVALUATION OF ZEBU NELLORE CATTLE BLOOD SAMPLES USING THE CELL-DYN 3500 HEMATOLOGY ANALYZER

    Alexandre Secorun Borges

    2014-12-01

    Full Text Available The Cell-dyn 3500 is a multiparameter flow cytometer, which may analyze samples from several species performing several simultaneous analyses. It is able to perform white blood cells, red blood cells and platelet counts, besides differential leukocyte counts, packed cell volume and hemoglobin determination. Cell-Dyn 3500 performs total leukocyte count both optically and by impedance. The equipment may choose one or other method, based on the reliability of the results. Erythrocyte and platelet counts are determined by impedance. Leukocyte differentiation is based on an optical principle, using separation in multiangular polarized light. The objective of this study was to compare the results of complete blood count of Zebu Nellore heifers from Celldyn 3500, with those obtained from a semi-automated cell counter (Celm CC 510 and the manual technique. Blood samples were collected from the jugular vein in 5 mL EDTA vacuum tubes from 58 Nellore heifers, at 24 months of age. Samples were processed in parallel in the three different techniques. Results were analyzed using paired t test, Pearson’s correlation and the Bland-Altmann method. There was a strong correlation for all parameters analyzed by Cell-Dyn 3500, manual method and semiautomated cell counter, except for basophils and monocytes counts. These results confirm that this analyzer is reliable for blood samples analysis of zebu cattle.

  8. GOssTo: a stand-alone application and a web tool for calculating semantic similarities on the Gene Ontology.

    Caniza, Horacio; Romero, Alfonso E; Heron, Samuel; Yang, Haixuan; Devoto, Alessandra; Frasca, Marco; Mesiti, Marco; Valentini, Giorgio; Paccanaro, Alberto

    2014-08-01

    We present GOssTo, the Gene Ontology semantic similarity Tool, a user-friendly software system for calculating semantic similarities between gene products according to the Gene Ontology. GOssTo is bundled with six semantic similarity measures, including both term- and graph-based measures, and has extension capabilities to allow the user to add new similarities. Importantly, for any measure, GOssTo can also calculate the Random Walk Contribution that has been shown to greatly improve the accuracy of similarity measures. GOssTo is very fast, easy to use, and it allows the calculation of similarities on a genomic scale in a few minutes on a regular desktop machine. alberto@cs.rhul.ac.uk GOssTo is available both as a stand-alone application running on GNU/Linux, Windows and MacOS from www.paccanarolab.org/gossto and as a web application from www.paccanarolab.org/gosstoweb. The stand-alone application features a simple and concise command line interface for easy integration into high-throughput data processing pipelines. © The Author 2014. Published by Oxford University Press.

  9. SedInConnect: a stand-alone, free and open source tool for the assessment of sediment connectivity

    Crema, Stefano; Cavalli, Marco

    2018-02-01

    There is a growing call, within the scientific community, for solid theoretic frameworks and usable indices/models to assess sediment connectivity. Connectivity plays a significant role in characterizing structural properties of the landscape and, when considered in combination with forcing processes (e.g., rainfall-runoff modelling), can represent a valuable analysis for an improved landscape management. In this work, the authors present the development and application of SedInConnect: a free, open source and stand-alone application for the computation of the Index of Connectivity (IC), as expressed in Cavalli et al. (2013) with the addition of specific innovative features. The tool is intended to have a wide variety of users, both from the scientific community and from the authorities involved in the environmental planning. Thanks to its open source nature, the tool can be adapted and/or integrated according to the users' requirements. Furthermore, presenting an easy-to-use interface and being a stand-alone application, the tool can help management experts in the quantitative assessment of sediment connectivity in the context of hazard and risk assessment. An application to a sample dataset and an overview on up-to-date applications of the approach and of the tool shows the development potential of such analyses. The modelled connectivity, in fact, appears suitable not only to characterize sediment dynamics at the catchment scale but also to integrate prediction models and as a tool for helping geomorphological interpretation.

  10. Improved double integral sliding mode MPPT controller based parameter estimation for a stand-alone photovoltaic system

    Chatrenour, Nasrin; Razmi, Hadi; Doagou-Mojarrad, Hasan

    2017-01-01

    Highlights: • IDISMC based MPPT algorithm is introduced. • Hurwitz stability theorem is used for switching surface coefficients computation. • GA approach is presented for parameter estimation of the stand-alone PV system. - Abstract: In this paper, an Improved Double Integral Sliding Mode MPPT Controller (IDISMC) for a stand-alone photovoltaic (PV) system is proposed. Performance of a sliding mode controller (SMC) is greatly influenced by the choice of the sliding surface. Switching surface coefficients were selected by the use of Hurwitz stability theorem. The IDISMC not only is robust against parametric and non-parametric uncertainties, but also has a very small steady-state error, thanks to the use of double integral of tracking voltage error in the definition of its sliding surface. For realistic simulation, Genetic Algorithm (GA) method was used to estimate parameters of solar panels model. The validity of the proposed double integral SMC in maximum power point tracking was approved by comparing the simulation results obtained for a sample PV system with the results of other methods.

  11. Comparison of pulp-mill-integrated hydrogen production from gasified black liquor with stand-alone production from gasified biomass

    Andersson, E.; Harvey, S.

    2007-01-01

    When gasified black liquor is used for hydrogen production, significant amounts of biomass must be imported. This paper compares two alternative options for producing hydrogen from biomass: (A) pulp-mill-integrated hydrogen production from gasified back liquor; and (B) stand-alone production of hydrogen from gasified biomass. The comparison assumes that the same amount of biomass that is imported in Alternative A is supplied to a stand-alone hydrogen production plant and that the gasified black liquor in Alternative B is used in a black liquor gasification combined cycle (BLGCC) CHP unit. The comparison is based upon equal amounts of black liquor fed to the gasifier, and identical steam and power requirements for the pulp mill. The two systems are compared on the basis of total CO 2 emission consequences, based upon different assumptions for the reference energy system that reflect different societal CO 2 emissions reduction target levels. Ambitions targets are expected to lead to a more CO 2 -lean reference energy system, in which case hydrogen production from gasified black liquor (Alternative A) is best from a CO 2 emissions' perspective, whereas with high CO 2 emissions associated with electricity production, hydrogen from gasified biomass and electricity from gasified black liquor (Alternative B) is preferable. (author)

  12. A Control Approach and Supplementary Controllers for a Stand-Alone System with Predominance of Wind Generation

    Tiago Lukasievicz

    2018-02-01

    Full Text Available This paper proposes a control approach and supplementary controllers for the operation of a hybrid stand-alone system composed of a wind generation unit and a conventional generation unit based on synchronous generator (CGU. The proposed controllers allow the islanded or isolated operation of small power systems with predominance of wind generation. As an advantage and a paradigm shift, the DC-link voltage of the wind unit is controlled by means of a conventional synchronous generator connected to the AC grid of the system. Two supplementary controllers, added to a diesel generator (DIG and to a DC dump load (DL, are proposed to control the DC-link voltage. The wind generation unit operates in V-f control mode and the DIG operates in PQ control mode, which allows the stand-alone system to operate either in wind-diesel (WD mode or in wind-only (WO mode. The strong influence of the wind turbine speed variations in the DC-link voltage is mitigated by a low-pass filter added to the speed control loop of the wind turbine. The proposed control approach does not require the use battery bank and ultra-capacitor to control the DC-link voltage in wind generation units based on fully rated converter.

  13. Optimization of the photovoltaic-hydrogen supply system of a stand-alone remote-telecom application

    Gomez, Guillermo; Martinez, Graciano; Galvez, Jose L.; Cuevas, Raquel; Maellas, Jesus [National Institute for Aerospace Technology (INTA), Renewable Energy Department, Ctra. Ajalvir km 4, E-28850 Torrejon de Ardoz, Madrid (Spain); Gila, Raul; Bueno, Emilio [Polytechnical School - Alcala de Henares University, Electronics Department, Campus Universitario, Ctra. De Madrid-Barcelona Km 33.600, Alcala de Henares, Madrid (Spain)

    2009-07-15

    Hydrogen is considered as the optimal carrier for the surplus energy storage from renewable resources. Although hydrogen and its application in fuel cell is considered as a high-cost energy system, some cost-efficient solutions have been found for their use in stand-alone applications, which usually depend on the variability of renewable sources that have to be oversized in order to reduce their dependence on external energy sources. This paper shows the results from the simulation of several alternatives of introducing hydrogen technologies to increase the independence of a remote-telecom application fed by photovoltaic panels. Hydrogen is obtained by electrolysis and it is used in a fuel cell when the renewable energy source is not enough to maintain the stand-alone application. TRNSYS simulation environment has been used for evaluating the proposed alternatives. The results show that the best configuration option is that considering the use of hydrogen as a way to storage the surplus of radiation and the management system can vary the number of photovoltaic panels assigned to feed the hydrogen generation, the batteries or the telecom application. (author)

  14. Human microRNA target analysis and gene ontology clustering by GOmir, a novel stand-alone application.

    Roubelakis, Maria G; Zotos, Pantelis; Papachristoudis, Georgios; Michalopoulos, Ioannis; Pappa, Kalliopi I; Anagnou, Nicholas P; Kossida, Sophia

    2009-06-16

    microRNAs (miRNAs) are single-stranded RNA molecules of about 20-23 nucleotides length found in a wide variety of organisms. miRNAs regulate gene expression, by interacting with target mRNAs at specific sites in order to induce cleavage of the message or inhibit translation. Predicting or verifying mRNA targets of specific miRNAs is a difficult process of great importance. GOmir is a novel stand-alone application consisting of two separate tools: JTarget and TAGGO. JTarget integrates miRNA target prediction and functional analysis by combining the predicted target genes from TargetScan, miRanda, RNAhybrid and PicTar computational tools as well as the experimentally supported targets from TarBase and also providing a full gene description and functional analysis for each target gene. On the other hand, TAGGO application is designed to automatically group gene ontology annotations, taking advantage of the Gene Ontology (GO), in order to extract the main attributes of sets of proteins. GOmir represents a new tool incorporating two separate Java applications integrated into one stand-alone Java application. GOmir (by using up to five different databases) introduces miRNA predicted targets accompanied by (a) full gene description, (b) functional analysis and (c) detailed gene ontology clustering. Additionally, a reverse search initiated by a potential target can also be conducted. GOmir can freely be downloaded BRFAA.

  15. Study on Soft Phase Locked Method to Solving the Synchronization Problem of Active Power Filter in Stand-alone Power Grid

    Zhuo, Fang; Wu, Longhui; Chen, Zhe

    2009-01-01

    on zero-cross detection can't work effectively in small rating stand-alone power grid. Then a soft phase locked loop with additional filter is proposed. It can lock the phase angle on to the positive sequence of fundamental voltage accurately and rapidly. It ensures the performance of APF applied...... in the small rating stand-alone power grid. Moreover, the soft phase locked loop is easy to be implemented in a Digital Signal Processor (DSP). Simulation and experimental results validate that the soft phase locked loop has satisfactory performance.......Traditional LC filters can't work stably in small rating stand-alone power grid. So active power filter (APF) is becoming an important tool to solve the power quality problem in small rating stand-alone power grid. In most current detection algorithm of APF, it needs a synchronizing signal. Firstly...

  16. Design of Malaria Diagnostic Criteria for the Sysmex XE-2100 Hematology Analyzer

    Campuzano-Zuluaga, Germán; Álvarez-Sánchez, Gonzalo; Escobar-Gallo, Gloria Elcy; Valencia-Zuluaga, Luz Marina; Ríos-Orrego, Alexandra Marcela; Pabón-Vidal, Adriana; Miranda-Arboleda, Andrés Felipe; Blair-Trujillo, Silvia; Campuzano-Maya, Germán

    2010-01-01

    Thick film, the standard diagnostic procedure for malaria, is not always ordered promptly. A failsafe diagnostic strategy using an XE-2100 analyzer is proposed, and for this strategy, malaria diagnostic models for the XE-2100 were developed and tested for accuracy. Two hundred eighty-one samples were distributed into Plasmodium vivax, P. falciparum, and acute febrile syndrome groups for model construction. Model validation was performed using 60% of malaria cases and a composite control group of samples from AFS and healthy participants from endemic and non-endemic regions. For P. vivax, two observer-dependent models (accuracy = 95.3–96.9%), one non–observer-dependent model using built-in variables (accuracy = 94.7%), and one non–observer-dependent model using new and built-in variables (accuracy = 96.8%) were developed. For P. falciparum, two non–observer-dependent models (accuracies = 85% and 89%) were developed. These models could be used by health personnel or be integrated as a malaria alarm for the XE-2100 to prompt early malaria microscopic diagnosis. PMID:20207864

  17. An ArcGIS analysis of Stand-alone GPS quality for Road Pricing

    Zabic, Martina

    2006-01-01

    The paper presents the methods and some of the result maps from a study of GPS quality in relation to road pricing in a dense urban area. Data from 500 cars were colleted over a two-year period in the Copenhagen region (Denmark). The data was analyzed in ArcGIS in order to determine whether the GPS...... quality and reliability is adequate for implementation of a road pricing system. The GPS log files was imported into ArcGIS and analyzed in relation to the digital road network and the density of the high rise areas in order to examine where the high buildings and narrow street canyons causes too many...

  18. Clinical and radiological outcome after anterior cervical discectomy and fusion with stand-alone empty polyetheretherketone (PEEK) cages.

    Shiban, Ehab; Gapon, Karina; Wostrack, Maria; Meyer, Bernhard; Lehmberg, Jens

    2016-02-01

    To evaluate long-term results after one-, two-, and three-level anterior cervical discectomy and fusion (ACDF) with stand-alone empty polyetheretherketone (PEEK) cages. We performed a retrospective review of a consecutive patient cohort that underwent ACDF with stand-alone empty PEEK cages between 2007 and 2010 with a minimum follow-up of 12 months. Radiographic follow-up included static and flexion/extension radiographs. Changes in the operated segments were measured and compared to radiographs directly after surgery. Clinical outcome was evaluated by a physical examination, pain visual analog scale (VAS), and health-related quality of life (HRQL) using the EuroQOL questionnaire (EQ-5D). Analysis of associations between fusion, subsidence, cervical alignment, and clinical outcome parameters were performed. Of 407 consecutive cases, 318 met all inclusion criteria. Follow-up data were obtained from 265 (83 %) cases. The mean age at presentation was 55 years and 139 patients were male (52 %). In the sample, 127, 125, and 13 patients had one-, two-, and three-level surgeries, respectively; 132 (49 %) presented with spondylotic cervical myelopathy and 133 (50 %) with cervical radiculopathy. Fusion was achieved in 85, 95, and 94 % of segments in one-, two-, and three-level surgeries, respectively. Non-fusion was associated with higher VAS pain levels. Radiographic adjacent segment disease (ASD) was observed in 20, 29, and 15 % in one-, two-, and three-level surgeries, respectively. ASD was associated with lower HRQL. Subsidence was observed in 25, 27, and 15 % of segments in one-, two-, and three-level surgeries, respectively. However, this had no influence on clinical outcome. Follow-up operations for symptomatic adjacent disc disease and implant failure at index level were needed in 16 (6 %) and four (1.5 %) cases, respectively. Younger age was associated with better clinical outcome. Multilevel surgery favored better myelopathy outcomes and fusion reduced overall

  19. Control aspects of the Schuchuli Village stand-alone photovoltaic power system

    Groumpos, P. P.; Culler, J. E.; Delombard, R.

    1984-11-01

    A photovoltaic power system in an Arizona Indian village was installed. The control subsystem of this photovoltaic power system was analyzed. The four major functions of the control subsystem are: (1) voltage regulation; (2) load management; (3) water pump control; and (4) system protection. The control subsystem functions flowcharts for the control subsystem operation, and a computer program that models the control subsystem are presented.

  20. Online retrieval of patient information by asynchronous communication between general purpose computer and stand-alone personal computer

    Tsutsumi, Reiko; Takahashi, Kazuei; Sato, Toshiko; Komatani, Akio; Yamaguchi, Koichi

    1988-01-01

    Asynchronous communication was made between host (FACOM M-340) and personal computer (OLIBETTIE S-2250) to get patient's information required for RIA test registration. The retrieval system consists of a keyboad input of six numeric codes, patient's ID, and a real time reply containing six parameters for the patient. Their identified parameters are patient's name, sex, date of birth (include area), department, and out- or inpatient. Linking this program to RIA registration program for individual patient, then, operator can input name of RIA test requested. Our simple retrieval program made a useful data network between different types of host and stand-alone personal computers, and enabled us accurate and labor-saving registration for RIA test. (author)

  1. Integration of hydrogen energy technologies in stand-alone power systems analysis of the current potential for applications

    Zoulias, E.I.; Lymberopoulos, N.; Tsoutsos, T.; Glockner, R.; Mydske, H.J.; Vosseler, I.; Gavalda, O.; Taylor, P.

    2006-01-01

    The European study entitled: 'Market Potential Analysis for Introduction of Hydrogen Energy Technology in Stand-Alone Power Systems (H-SAPS)' aimed to establish a broad understanding of the market potential for H-SAPS and provide a basis for promoting in wide scale new technological applications. The scope of the study was limited to small and medium installations, up to a few hundred kW power rating and based on RE as the primary energy source. The potential for hydrogen technology in SAPS was investigated through an assessment of the technical potential for hydrogen, the market analysis and the evaluation of external factors. The results are mostly directed towards action by governments and the research community but also industry involvement is identified. The results include targeted market research, establishment of individual cost targets, regulatory changes to facilitate alternative grid solutions, information and capacity building, focused technology research and bridging the technology gaps. (author)

  2. A soil-canopy scheme for use in a numerical model of the atmosphere: 1D stand-alone model

    Kowalczyk, E. A.; Garratt, J. R.; Krummel, P. B.

    We provide a detailed description of a soil-canopy scheme for use in the CSIRO general circulation models (GCMs) (CSIRO-4 and CSIRO-9), in the form of a one-dimensional stand-alone model. In addition, the paper documents the model's ability to simulate realistic surface fluxes by comparison with mesoscale model simulations (involving more sophisticated soil and boundary-layer treatments) and observations, and the diurnal range in surface quantities, including extreme maximum surface temperatures. The sensitivity of the model to values of the surface resistance is also quantified. The model represents phase 1 of a longer-term plan to improve the atmospheric boundary layer (ABL) and surface schemes in the CSIRO GCMs.

  3. Development of stand-alone risk assessment software for optimized maintenance planning of power plant facilities

    Choi, Woo Sung; Song, Gee Wook; Kim, Bum Shin; Chang, Sung Ho; Lee, Sang Min

    2015-01-01

    Risk-Risk-based inspection (RBI) has been developed in order to identify risky equipment that can cause major accidents or damages in large-scale plants. This assessment evaluates the equipment's risk, categorizes their priorities based on risk level, and then determines the urgency of their maintenance or allocates maintenance resources. An earlier version of the risk-based assessment software is already installed within the equipment management system; however, the assessment is based on examination by an inspector, and the results can be influenced by his subjective judgment, rather than assessment being based on failure probability. Moreover, the system is housed within a server, which limits the inspector's work space and time, and such a system can be used only on site. In this paper, the development of independent risk-based assessment software is introduced; this software calculates the failure probability by an analytical method, and analyzes the field inspection results, as well as inspection effectiveness. It can also operate on site, since it can be installed on an independent platform, and has the ability to generate an I/O function for the field inspection results regarding the period for an optimum maintenance cycle. This program will provide useful information not only to the field users who are participating in maintenance, but also to the engineers who need to decide whether to extend the life cycle of the power machinery or replace only specific components

  4. Stand-alone core sensitivity and uncertainty analysis of ALFRED from Monte Carlo simulations

    Pérez-Valseca, A.-D.; Espinosa-Paredes, G.; François, J.L.; Vázquez Rodríguez, A.; Martín-del-Campo, C.

    2017-01-01

    Highlights: • Methodology based on Monte Carlo simulation. • Sensitivity analysis of Lead Fast Reactor (LFR). • Uncertainty and regression analysis of LFR. • 10% change in the core inlet flow, the response in thermal power change is 0.58%. • 2.5% change in the inlet lead temperature the response is 1.87% in power. - Abstract: The aim of this paper is the sensitivity and uncertainty analysis of a Lead-Cooled Fast Reactor (LFR) based on Monte Carlo simulation of sizes up to 2000. The methodology developed in this work considers the uncertainty of sensitivities and uncertainty of output variables due to a single-input-variable variation. The Advanced Lead fast Reactor European Demonstrator (ALFRED) is analyzed to determine the behavior of the essential parameters due to effects of mass flow and temperature of liquid lead. The ALFRED core mathematical model developed in this work is fully transient, which takes into account the heat transfer in an annular fuel pellet design, the thermo-fluid in the core, and the neutronic processes, which are modeled with point kinetic with feedback fuel temperature and expansion effects. The sensitivity evaluated in terms of the relative standard deviation (RSD) showed that for 10% change in the core inlet flow, the response in thermal power change is 0.58%, and for 2.5% change in the inlet lead temperature is 1.87%. The regression analysis with mass flow rate as the predictor variable showed statistically valid cubic correlations for neutron flux and linear relationship neutron flux as a function of the lead temperature. No statistically valid correlation was observed for the reactivity as a function of the mass flow rate and for the lead temperature. These correlations are useful for the study, analysis, and design of any LFR.

  5. Leadership in Dental Hygiene Degree Completion Programs: A Pilot Study Comparing Stand-Alone Leadership Courses and Leadership-Infused Curricula.

    Smith, Michelle L; Gurenlian, JoAnn R; Freudenthal, Jacqueline J; Farnsworth, Tracy J

    2016-05-01

    The aim of this study was to define the extent to which leadership and leadership skills are taught in dental hygiene degree completion programs by comparing stand-alone leadership courses/hybrid programs with programs that infuse leadership skills throughout the curricula. The study involved a mixed-methods approach using qualitative and quantitative data. Semi-structured interviews were conducted with program directors and faculty members who teach a stand-alone leadership course, a hybrid program, or leadership-infused courses in these programs. A quantitative comparison of course syllabi determined differences in the extent of leadership content and experiences between stand-alone leadership courses and leadership-infused curricula. Of the 53 U.S. dental hygiene programs that offer degree completion programs, 49 met the inclusion criteria, and 19 programs provided course syllabi. Of the program directors and faculty members who teach a stand-alone leadership course or leadership-infused curriculum, 16 participated in the interview portion of the study. The results suggested that competencies related to leadership were not clearly defined or measurable in current teaching. Reported barriers to incorporating a stand-alone leadership course included overcrowded curricula, limited qualified faculty, and lack of resources. The findings of this study provide a synopsis of leadership content and gaps in leadership education for degree completion programs. Suggested changes included defining a need for leadership competencies and providing additional resources to educators such as courses provided by the American Dental Education Association and the American Dental Hygienists' Association.

  6. The Research on Second-Order ADRC Algorithm of Using Wind Turbine Virtual Inertia to Participate in Primary Frequency Regulation in a Small Stand-Alone Microgrid

    Wang Yi

    2018-01-01

    Full Text Available In order to improve the transient stability of frequency in a small stand-alone microgrid (SSM, this paper takes a SSM composed of a direct-drive permanent magnet synchronous generator (D-PMSG and a micro gas turbine (MGT as the background and uses wind turbine generator (WTG virtual inertia (VI to participate in the primary (short-term system frequency regulation. First of all, this paper constructs a grid-connected model composed of a WTG and a MGT, analyzes the WTG virtual inertia frequency regulation mechanism, and explains the principle of proportional-differentiation (PD virtual inertia control (VIC and its shortcomings. Secondly, the paper introduces the structure principle of n-order active disturbance rejection control (ADRC and deduces the design process of second-order ADRC-VIC. Finally, through the simulation and experimental verification, comparing the frequency perturbation of without-VIC, PD-VIC, and ADRC-VIC, it is concluded that PD-VIC and ADRC-VIC both can use the WTG virtual inertia to participate in the primary frequency regulation. The frequency regulation effect of ADRC-VIC is better than PD-VIC, ADRC-VIC can extend the rotor speed recovery time and avoid overshoot, and its frequency fluctuation amplitude and settling time are obviously improved, and ADRC-VIC can effectively avoid the overshoot phenomenon of the MGT output power.

  7. Development of Stand Alone Application Tool for Processing and Quality Measurement of Weld Imperfection Image Captured by μ-Focused Digital Radiography Using MATLAB- Based Graphical User Interface

    PZ Nadila

    2012-12-01

    Full Text Available Digital radiography incresingly is being applied in the fabrication industry. Compared to film- based radiography, digitally radiographed images can be acquired with less time and fewer exposures. However, noises can simply occur on the digital image resulting in a low-quality result. Due to this and the system’s complexity, parameters’ sensitivity, and environmental effects, the results can be difficult to interpret, even for a radiographer. Therefore, the need of an application tool to improve and evaluate the image is becoming urgent. In this research, a user-friendly tool for image processing and image quality measurement was developed. The resulting tool contains important components needed by radiograph inspectors in analyzing defects and recording the results. This tool was written by using image processing and the graphical user interface development environment and compiler (GUIDE toolbox available in Matrix Laboratory (MATLAB R2008a. In image processing methods, contrast adjustment, and noise removal, edge detection was applied. In image quality measurement methods, mean square error (MSE, peak signal-to-noise ratio (PSNR, modulation transfer function (MTF, normalized signal-to-noise ratio (SNRnorm, sensitivity and unsharpness were used to measure the image quality. The graphical user interface (GUI wass then compiled to build a Windows, stand-alone application that enables this tool to be executed independently without the installation of MATLAB.

  8. A Study on Electric Power Smoothing System for Lead-Acid Battery of Stand-Alone Natural Energy Power System Using EDLC

    Jia, Yan; Shibata, Ryosuke; Yamamura, Naoki; Ishida, Muneaki

    To resolve energy shortage and global warming problem, renewable natural resource and its power system has been gradually generalizing. However, the power fluctuation suppressing in short period and the balance control of consumption and supply in long period are two of main problems that need to be resolved urgently in natural energy power system. In Stand-alone Natural Energy Power System (SNEPS) with power energy storage devices, power fluctuation in short period is one of the main reasons that recharge cycle times increase and lead-acid battery early failure. Hence, to prolong the service life of lead-acid battery and improve power quality through suppressing the power fluctuation, we proposed a method of electric power smoothing for lead-acid battery of SNEPS using bi-directional Buck/Boost converter and Electric Double Layer Capacitor (EDLC) in this paper. According to the test data of existing SNEPS, a power fluctuation condition is selected and as an example to analyze the validity of the proposed method. The analysis of frequency characteristics indicates the power fluctuation is suppressed a desired range in the target frequency region. The experimental results of confirmed the feasibility of the proposed system and the results well satisfy the requirement of system design.

  9. Direct Flux Control for Stand-Alone Operation Brushless Doubly Fed Induction Generators Using a Resonant-Based Sliding-Mode Control Approach

    Kai Ji

    2018-04-01

    Full Text Available In this paper, a novel voltage control strategy for stand-alone operation brushless doubly fed induction generators for variable speed constant frequency wind energy conversion systems was presented and discussed. Based on the model of the power generation system, the proposed direct flux control strategy employs a nonlinear reduced-order generalized integrator-based resonant sliding-mode control approach to directly calculate and regulate the output value of converter which the control winding stator requires so as to eliminate its instantaneous errors, without involving any synchronous rotating coordinate transformations. The stability, robustness and convergence capability of the proposed control strategy were described and analyzed. Owing to the fact no additional current control inner loops are involved, the system configuration is therefore simplified and the dynamic performance enhanced. A constant converter switching frequency was achieved by using space vector pulse width modulation, which reduces the harmonics of the generator terminal voltage. In addition, the feasibility and validity of the proposed scheme is verified by experiments, and excellent steady and transient performance is achieved.

  10. Stand-alone microgrids

    Bauer, P.; Weldemariam, L.E.; Raijen, E.

    2011-01-01

    Abstract- A hybrid power system (HPS) which consists of diesel Genset, PV -arrays and wind turbines with energy storing and power electronic devices is discussed in this paper. An inventory of different connection topologies is made for some of the sources that generate AC power and others that

  11. Epicardial, Biatrial Ablation With Integrated Uni-bipolar Radiofrequency Technology in Stand-alone Persistent Atrial Fibrillation.

    Rosati, Fabrizio; Muneretto, Claudio; Merati, Elisa; Polvani, Gianluca; Moltrasio, Massimo; Tondo, Claudio; Curnis, Antonio; Cerini, Manuel; Metras, Alexandre; Bisleri, Gianluigi

    Although minimally invasive approaches for surgical treatment of stand-alone atrial fibrillation have gained popularity for the past decade, ablation technology and extensive lesion sets play a major role in the achievement of a successful procedure, especially in presence of persistent and long-standing persistent atrial fibrillation. We evaluated clinical outcomes after totally endoscopic biatrial epicardial ablation of persistent atrial fibrillation with a novel integrated uni-bipolar radiofrequency device. Forty-nine (49) consecutive patients with stand-alone atrial fibrillation underwent right-sided monolateral thoracoscopic surgical ablation with a novel integrated uni-bipolar radiofrequency energy delivery and temperature-controlled technology. Atrial fibrillation was persistent in 13 (26.5%) of 49 and long-standing persistent in 36 (73.5%) of 49 patients. Mean ± SD age was 60.6 ± 10.3 years. Median duration of atrial fibrillation was 74 months. Mean ± SD left atrial diameter was 44.7 ± 4.0 mm. Epicardial en bloc isolation of all pulmonary veins (box lesion) and additional ablation of the right atrial free wall was successfully performed via minimally invasive approach without any intraoperative and postoperative major complications. Intraoperative entrance and exit block was achieved in 77.5% (38/49) and 91.8% (45/49) of patients, respectively. Mean ± SD ablation time was 16.3 ± 4.8 minutes. No intensive care unit stay was required. Postoperative sinus rhythm was achieved in 93.8% (30/32) patients, and no pacemaker implantation was required. At 13 months, 87.7% (43/49) of patients were in sinus rhythm; 71.4% (35/49) were free from antiarrhythmic drugs and 75.5% (37/49) from oral anticoagulation. Integrated uni-bipolar radiofrequency ablation technology showed to be effective for the surgical treatment of atrial fibrillation with a total endoscopic approach. A versapolar suction device with extensive right-left atrial lesion set may further improve

  12. A Novel Method for Fast Configuration of Energy Storage Capacity in Stand-Alone and Grid-Connected Wind Energy Systems

    Haixiang Zang

    2016-12-01

    Full Text Available In this paper, a novel method is proposed and applied to quickly calculate the capacity of energy storage for stand-alone and grid-connected wind energy systems, according to the discrete Fourier transform theory. Based on practical wind resource data and power data, which are derived from the American Wind Energy Technology Center and HOMER software separately, the energy storage capacity of a stand-alone wind energy system is investigated and calculated. Moreover, by applying the practical wind power data from a wind farm in Fujian Province, the energy storage capacity for a grid-connected wind system is discussed in this paper. This method can also be applied to determine the storage capacity of a stand-alone solar energy system with practical photovoltaic power data.

  13. Development of a Laser-Powered Dielectric Structure-Based Accelerator as a Stand-Alone Particle Source

    Yoder, R. B.; Travish, G.; Arab, E. R.; Fong, D.; Hoyer, Z.; Lacroix, U. H.; Vartanian, N.; Rosenzweig, J. B.

    2010-01-01

    An experimental program to develop and build a dielectric-based slab-symmetric structure (the micro-accelerator platform, or MAP) for generating and accelerating low-energy electrons is underway at UCLA and Manhattanville College. This optical acceleration structure is effectively a resonant cavity powered by a side-coupled laser, and has applications as a radiation source for medicine or industry. We present recent experimental and computational results on the accelerator, and progress toward its incorporation into a self-contained particle source. Such a particle source would incorporate a micron-scale electron emitter and a non-relativistic capture region to enable self-injection into the synchronous field within the accelerator. A prototype of the accelerator itself has been constructed from candidate dielectric materials using micromanufacturing techniques; the current status of the testing program is described. A novel electron emitter incorporating pyroelectric crystals with field-enhancing tips has been demonstrated to produce steady currents; the results are dependent on tip geometry, and appear suitable for injection into a microstructure. Extension of the MAP concept to non-relativistic velocities, as in the stand-alone source, requires a tapered structure that gives rise to numerous complications including beam defocusing and manufacturing challenges; approaches for addressing these complications are mentioned.

  14. Stand-alone power systems for the future: Optimal design, operation and control of solar-hydrogen energy systems

    Ulleberg, Oeystein

    1999-12-31

    This thesis gives a systematic review of the fundamentals of energy systems, the governing physical and chemical laws related to energy, inherent characteristics of energy system, and the availability of the earth`s energy. It shows clearly why solar-hydrogen systems are one of the most viable options for the future. The main subject discussed is the modelling of SAPS (Stand-Alone Power Systems), with focus on photovoltaic-hydrogen energy systems. Simulation models for a transient simulation program are developed for PV-H{sub 2} components, including models for photovoltaics, water electrolysis, hydrogen storage, fuel cells, and secondary batteries. A PV-H{sub 2} demonstration plant in Juelich, Germany, is studied as a reference plant and the models validated against data from this plant. Most of the models developed were found to be sufficiently accurate to perform short-term system simulations, while all were more than accurate enough to perform long-term simulations. Finally, the verified simulation models are used to find the optimal operation and control strategies of an existing PV-H{sub 2} system. The main conclusion is that the simulation methods can be successfully used to find optimal operation and control strategies for a system with fixed design, and similar methods could be used to find alternative system designs. 148 refs., 78 figs., 31 tabs.

  15. Power fluctuations suppression of stand-alone hybrid generation combining solar photovoltaic/wind turbine and fuel cell systems

    Ahmed, Nabil A.; Miyatake, Masafumi; Al-Othman, A.K.

    2008-01-01

    In this paper a hybrid energy system combining variable speed wind turbine, solar photovoltaic and fuel cell generation systems is presented to supply continuous power to residential power applications as stand-alone loads. The wind and photovoltaic systems are used as main energy sources while the fuel cell is used as secondary or back-up energy source. Three individual dc-dc boost converters are used to control the power flow to the load. A simple and cost effective control with dc-dc converters is used for maximum power point tracking and hence maximum power extracting from the wind turbine and the solar photovoltaic systems. The hybrid system is sized to power a typical 2 kW/150 V dc load as telecommunication power plants or ac residential power applications in isolated islands continuously throughout the year. The results show that even when the sun and wind are not available; the system is reliable and available and it can supply high-quality power to the load. The simulation results which proved the accuracy of the proposed controllers are given to demonstrate the availability of the proposed system in this paper. Also, a complete description of the management and control system is presented

  16. Comparison of Turkey’s Geographical Regions in terms of Stand-Alone PV System Design and Cost Parameters

    Nevzat Onat

    2017-01-01

    Full Text Available Stand-alone photovoltaic (SAPV systems are widely used in rural areas where there is no national grid or as a precaution against power outages. In this study, technical and economic analysis of a SAPV system was carried out using meteorological data for 75 province centers in seven geographical regions of Turkey. Obtained results for each province center were separated by geographical area. The averages of the centers for each region are taken as output. A calculation algorithm based on MsExcel has been established for these operations. The analyses made with the developed algorithm are repeated for five different scenarios that they cover periods of time when a constant strong load is active for all seasons (winter, spring, summer, and autumn and all year round. The developed algorithm calculates the life-cycle cost, the unit energy cost, the electrical capacity utilization rate, the amount of generated/excess energy per month, the initial investment/replacement, and operating and maintenance (O&M costs of each element. As a result, geographical regions of Turkey are compared in terms of these outputs graphically. Further investigations may include the sale of excess energy generated, small-scale PV system cost factors parallel to the grid, and the effects of government incentives.

  17. A stand alone computer system to aid the development of mirror fusion test facility RF heating systems

    Thomas, R.A.

    1983-01-01

    The Mirror Fusion Test Facility (MFTF-B) control system architecture requires the Supervisory Control and Diagnostic System (SCDS) to communicate with a LSI-11 Local Control Computer (LCC) that in turn communicates via a fiber optic link to CAMAC based control hardware located near the machine. In many cases, the control hardware is very complex and requires a sizable development effort prior to being integrated into the overall MFTF-B system. One such effort was the development of the Electron Cyclotron Resonance Heating (ECRH) system. It became clear that a stand alone computer system was needed to simulate the functions of SCDS. This paper describes the hardware and software necessary to implement the SCDS Simulation Computer (SSC). It consists of a Digital Equipment Corporation (DEC) LSI-11 computer and a Winchester/Floppy disk operating under the DEC RT-11 operating system. All application software for MFTF-B is programmed in PASCAL, which allowed us to adapt procedures originally written for SCDS to the SSC. This nearly identical software interface means that software written during the equipment development will be useful to the SCDS programmers in the integration phase

  18. Stand-alone power systems for the future: Optimal design, operation and control of solar-hydrogen energy systems

    Ulleberg, Oeystein

    1998-12-31

    This thesis gives a systematic review of the fundamentals of energy systems, the governing physical and chemical laws related to energy, inherent characteristics of energy system, and the availability of the earth`s energy. It shows clearly why solar-hydrogen systems are one of the most viable options for the future. The main subject discussed is the modelling of SAPS (Stand-Alone Power Systems), with focus on photovoltaic-hydrogen energy systems. Simulation models for a transient simulation program are developed for PV-H{sub 2} components, including models for photovoltaics, water electrolysis, hydrogen storage, fuel cells, and secondary batteries. A PV-H{sub 2} demonstration plant in Juelich, Germany, is studied as a reference plant and the models validated against data from this plant. Most of the models developed were found to be sufficiently accurate to perform short-term system simulations, while all were more than accurate enough to perform long-term simulations. Finally, the verified simulation models are used to find the optimal operation and control strategies of an existing PV-H{sub 2} system. The main conclusion is that the simulation methods can be successfully used to find optimal operation and control strategies for a system with fixed design, and similar methods could be used to find alternative system designs. 148 refs., 78 figs., 31 tabs.

  19. Modeling and control design of a stand alone wind energy conversion system based on functional model predictive control

    Kassem, Ahmed M. [Beni-Suef University, Electrical Dept., Beni Suef (Egypt)

    2012-09-15

    This paper investigates the application of the model predictive control (MPC) approach to control the voltage and frequency of a stand alone wind generation system. This scheme consists of a wind turbine which drives an induction generator feeding an isolated load. A static VAR compensator is connected at the induction generator terminals to regulate the load voltage. The rotor speed, and thereby the load frequency are controlled via adjusting the mechanical power input using the blade pitch-angle. The MPC is used to calculate the optimal control actions including system constraints. To alleviate computational effort and to reduce numerical problems, particularly in large prediction horizon, an exponentially weighted functional model predictive control (FMPC) is employed. Digital simulations have been carried out in order to validate the effectiveness of the proposed scheme. The proposed controller has been tested through step changes in the wind speed and the load impedance. Simulation results show that adequate performance of the proposed wind energy scheme has been achieved. Moreover, this scheme is robust against the parameters variation and eliminates the influence of modeling and measurement errors. (orig.)

  20. Modeling and Experimental Test of Grid-Tied Photovoltaic Cell Emulating System in the Stand-alone Mode

    Vu Minh Phap

    2017-06-01

    Full Text Available In recent decades, generation of electricity from solar arrays has been increased to meet the world's growing energy demand. However, the utilization rate of the power conditioner in the grid-tied solar power system is low because the operation of solar panels is dependent on sunlight. Thus, we studied the method that the small scale wind power generating system in size from a few hundred watts to two or three kilowatts can be connected to the grid-tied power conditioner of the solar power system for residential applications with low power ratings (single phase, size is limited to 10kW by emulating characteristic of the solar panel. In this paper, we introduce the application of the grid-tied PV cell emulating system in the stand-alone mode to improve the utilization rate of the power conditioner. The simulation and experimental test results verify that the PV cell emulating system can operate the power conditioner of the gridtied solar power system.

  1. Techno-economic analysis of stand-alone photovoltaic/wind/battery/hydrogen systems for very small-scale applications

    Stojković Saša M.

    2016-01-01

    Full Text Available The paper presents the results of a technical and economic analysis of three stand-alone hybrid power systems based on renewable energy sources which supply a specific group of low-power consumers. This particular case includes measuring sensors and obstacle lights on a meteorological mast for wind measurements requiring an uninterrupted power supply in cold climate conditions. Although these low-power (100 W measuring sensors and obstacle lights use little energy, their energy consumption is not the same as the available solar energy obtained on a daily or seasonal basis. In the paper, complementarity of renewable energy sources was analysed, as well as one of short-term lead-acid battery-based storage and seasonal, hydrogen-based (electrolyser, H2 tank, and fuel cells storage. These relatively complex power systems were proposed earlier for high-power consumers only, while this study specifically highlights the role of the hydrogen system for supplying low-power consumers. The analysis employed a numerical simulation method using the HOMER software tool. The results of the analysis suggest that solar and wind-solar systems, which involve meteorological conditions as referred to in this paper, include a relatively large number of lead-acid batteries. Additionally, the analysis suggests that the use of hydrogen power systems for supplying low power-consumers is entirely justifiable, as it significantly reduces the number of batteries (two at minimum in this particular case. It was shown that the increase in costs induced by the hydrogen system is acceptable.

  2. An adaptive artificial neural network model for sizing stand-alone photovoltaic systems: Application for isolated sites in Algeria

    Mellit, A.; Benghanem, M.; Hadj Arab, A.; Guessoum, G.

    2004-07-01

    In this paper we investigate, by using an adaptive Artificial Neural Network (ANN), in order to find a suitable model for sizing Stand-Alone Photovoltaic (SAPV) systems, based on a minimum of input data. This model combines Radial Basis Function (RBF) network and Infinite Impulse Response (IIR) filter in order to accelerate the convergence of the network. For the sizing of a photovoltaic (PV) system, we need to determine the optimal sizing coefficients (K PV , K B . These coefficients allow us to determine the number of solar panels and storage batteries necessary to satisfy a given consumption, especially in isolated sites where the global solar radiation data is not always available and which are considered the most important parameters for sizing a PV system. Obtained results by classical models (analytical, numerical, analytical- numerical, B-spline function) and new models like feed-forward (MLP), radial basis function (RBF), MLP-IIR and RBF-IIR have been compared with experimental sizing coefficients in order to illustrate the accuracy of the results of the new developed model. This model has been trained by using 200 known optimal sizing coefficients corresponding to 200 locations in Algeria. In this way, the adaptive model was trained to accept and even handle a number of unusual cases, the unknown validation sizing coefficients set produced very set accurate estimation and a correlation coefficient of 98% was obtained between the calculated and that estimated by the RBF-IIR model. This result indicates that the proposed method can be successfully used for the estimation of optimal sizing coefficients of SAPV systems for any locations in Algeria, but the methodology can be generalized using different locations over the world. (author)

  3. System dynamic model and charging control of lead-acid battery for stand-alone solar PV system

    Huang, B.J.

    2010-05-01

    The lead-acid battery which is widely used in stand-alone solar system is easily damaged by a poor charging control which causes overcharging. The battery charging control is thus usually designed to stop charging after the overcharge point. This will reduce the storage energy capacity and reduce the service time in electricity supply. The design of charging control system however requires a good understanding of the system dynamic behaviour of the battery first. In the present study, a first-order system dynamics model of lead-acid battery at different operating points near the overcharge voltage was derived experimentally, from which a charging control system based on PI algorithm was developed using PWM charging technique. The feedback control system for battery charging after the overcharge point (14 V) was designed to compromise between the set-point response and the disturbance rejection. The experimental results show that the control system can suppress the battery voltage overshoot within 0.1 V when the solar irradiation is suddenly changed from 337 to 843 W/m2. A long-term outdoor test for a solar LED lighting system shows that the battery voltage never exceeded 14.1 V for the set point 14 V and the control system can prevent the battery from overcharging. The test result also indicates that the control system is able to increase the charged energy by 78%, as compared to the case that the charging stops after the overcharge point (14 V). © 2010 Elsevier Ltd. All rights reserved.

  4. Stand-alone front-end system for high- frequency, high-frame-rate coded excitation ultrasonic imaging.

    Park, Jinhyoung; Hu, Changhong; Shung, K Kirk

    2011-12-01

    A stand-alone front-end system for high-frequency coded excitation imaging was implemented to achieve a wider dynamic range. The system included an arbitrary waveform amplifier, an arbitrary waveform generator, an analog receiver, a motor position interpreter, a motor controller and power supplies. The digitized arbitrary waveforms at a sampling rate of 150 MHz could be programmed and converted to an analog signal. The pulse was subsequently amplified to excite an ultrasound transducer, and the maximum output voltage level achieved was 120 V(pp). The bandwidth of the arbitrary waveform amplifier was from 1 to 70 MHz. The noise figure of the preamplifier was less than 7.7 dB and the bandwidth was 95 MHz. Phantoms and biological tissues were imaged at a frame rate as high as 68 frames per second (fps) to evaluate the performance of the system. During the measurement, 40-MHz lithium niobate (LiNbO(3)) single-element lightweight (<;0.28 g) transducers were utilized. The wire target measure- ment showed that the -6-dB axial resolution of a chirp-coded excitation was 50 μm and lateral resolution was 120 μm. The echo signal-to-noise ratios were found to be 54 and 65 dB for the short burst and coded excitation, respectively. The contrast resolution in a sphere phantom study was estimated to be 24 dB for the chirp-coded excitation and 15 dB for the short burst modes. In an in vivo study, zebrafish and mouse hearts were imaged. Boundaries of the zebrafish heart in the image could be differentiated because of the low-noise operation of the implemented system. In mouse heart images, valves and chambers could be readily visualized with the coded excitation.

  5. Effects of a stand-alone web-based electronic screening and brief intervention targeting alcohol use in university students of legal drinking age: A randomized controlled trial.

    Ganz, Thomas; Braun, Michael; Laging, Marion; Schermelleh-Engel, Karin; Michalak, Johannes; Heidenreich, Thomas

    2018-02-01

    Many intervention efforts targeting student drinking were developed to address US college students, which usually involves underage drinking. It remains unclear, if research evidence from these interventions is generalizable to university and college students of legal drinking age, e.g., in Europe. To evaluate the effectiveness of a translated and adapted version of the eCHECKUP TO GO, applied as stand-alone web-based electronic screening and brief intervention (e-SBI), in German university students at risk for hazardous drinking. A fully automated web-based two-arm parallel-group randomized controlled trial was conducted. Participants were randomized to an e-SBI or assessment-only (AO) condition. The current paper analyzed students with baseline AUDIT-C scores ≥3 for women and ≥4 for men (sample at baseline: e-SBI [n=514], AO [n=467]; 3-month follow-up: e-SBI [n=194], AO [n=231]; 6-month follow-up: e-SBI [n=146], AO [n=200]). The primary outcome was prior four weeks' alcohol consumption. Secondary outcomes were frequency of heavy drinking occasions, peak blood alcohol concentration, and number of alcohol-related problems. Mixed linear model analyses revealed significant interaction effects between groups and time points on the primary outcome after 3 and 6months. Compared to students in the AO condition, students in the e-SBI condition reported consuming 4.11 fewer standard drinks during the previous four weeks after 3months, and 4.78 fewer standard drinks after 6months. Mixed results were found on secondary outcomes. The results indicate that evidence on and knowledge of web-based e-SBIs based on US college student samples is transferable to German university students of legal drinking age. However, knowledge of what motivates students to complete programs under voluntary conditions, although rare, is needed. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. Post-processing in cardiovascular computed tomography. Performance of a client server solution versus a stand-alone solution

    Luecke, C.; Foldyna, B.; Andres, C.; Grothoff, M.; Nitzsche, S.; Gutberlet, M.; Lehmkuhl, L.; Boehmer-Lasthaus, S.

    2014-01-01

    Purpose: To compare the performance of server-based (CSS) versus stand-alone post-processing software (ES) for the evaluation of cardiovascular CT examinations (cvCT) and to determine the crucial steps. Data of 40 patients (20 patients for coronary artery evaluation and 20 patients prior to transcatheter aortic valve implantation [TAVI]) were evaluated by 5 radiologists with CSS and ES. Data acquisition was performed using a dual-source 128-row CT unit (SOMATOM Definition Flash, Siemens, Erlangen, Germany) and a 64-row CT unit (Brilliance 64, Philips, Hamburg, Germany). The following workflow was evaluated: Data loading, aorta and coronary segmentation, curved multiplanar reconstruction (cMPR) and 3 D volume rendering technique (3D-VRT), measuring of coronary artery stenosis and planimetry of the aortic annulus. The time requirement and subjective quality for the workflow were evaluated. The coronary arteries as well as the TAVI data could be evaluated significantly faster with CSS (5.5 ± 2.9 min and 8.2 ± 4.0 min, respectively) than with ES (13.9 ± 5.2 min and 15.2 ± 10.9 min, respectively, p = 0.01). Segmentation of the aorta (CSS: 1.9 ± 2.0 min, ES: 3.7 ± 3.3 min), generating cMPR of coronaries (CSS: 0.5 ± 0.2 min, ES: 5.1 ± 2.6 min), aorta and iliac vessels (CSS: 0.5 ± 0.4 min and 0.4 ± 0.4 min, respectively, ES: 1.6 ± 0.7 min and 2.8 ± 3 min, respectively) could be performed significantly faster with CSS than with ES with higher quality of cMPR, measuring of coronary stenosis and 3D-VRT (p < 0.05). Evaluation of cvCT can be accomplished significantly faster and better with CSS than with ES. The segmentation remains the most time-consuming workflow step, so optimization of segmentation algorithms could improve performance even further.

  7. A compact seven switches topology and reduced DC-link capacitor size for single-phase stand-alone PV system with hybrid energy storages

    Liu, Xiong; Wang, Peng; Loh, Poh Chiang

    2011-01-01

    Single-phase stand-alone PV system is suitable for household applications in remote area. Hybrid battery/ultra-capacitor energy storage can reduce charge and discharge cycles and avoid deep discharges of battery. This paper proposes a compact seven switches structure for stand-alone PV system......, which otherwise needs nine switches configuration, inclusive of one switch for boost converter, four switches for single-phase inverter and four switches for two DC/DC converters of battery and ultra-capacitor. It is well-known that a bulky DC-link capacitor is always required to absorb second......-order harmonic current caused by single-phase inverter. In the proposed compact topology, a small size DC-link capacitor can achieve the same function through charging/discharging control of ultra-capacitor to mitigate second-order ripple current. Simulation results are provided to validate the effectiveness...

  8. SoC-Based Output Voltage Control for BESS with a Lithium-Ion Battery in a Stand-Alone DC Microgrid

    Seung-Yeong Yu

    2016-11-01

    Full Text Available This paper proposes a new DC output voltage control for a battery energy storage system (BESS with a lithium-ion battery based on the state of charge (SoC. The proposed control scheme was verified through computer simulations for a typical stand-alone DC microgrid, which consists of a BESS, photovoltaic (PV panel, engine generator (EG, and DC load. A scaled hardware prototype for a stand-alone DC microgrid was set up in the lab, in which the proposed control scheme was loaded in a DSP controller. The experimental results were compared with the simulation results for performance verification. The proposed control scheme provides relatively lower variation of the DC grid voltage than the conventional droop control.

  9. Biomechanical comparison of a new stand-alone anterior lumbar interbody fusion cage with established fixation techniques – a three-dimensional finite element analysis

    Hsieh Pang-Hsing

    2008-06-01

    Full Text Available Abstract Background Initial promise of a stand-alone interbody fusion cage to treat chronic back pain and restore disc height has not been realized. In some instances, a posterior spinal fixation has been used to enhance stability and increase fusion rate. In this manuscript, a new stand-alone cage is compared with conventional fixation methods based on the finite element analysis, with a focus on investigating cage-bone interface mechanics and stress distribution on the adjacent tissues. Methods Three trapezoid 8° interbody fusion cage models (dual paralleled cages, a single large cage, or a two-part cage consisting of a trapezoid box and threaded cylinder were created with or without pedicle screws fixation to investigate the relative importance of the screws on the spinal segmental response. The contact stress on the facet joint, slip displacement of the cage on the endplate, and rotational angle of the upper vertebra were measured under different loading conditions. Results Simulation results demonstrated less facet stress and slip displacement with the maximal contact on the cage-bone interface. A stand-alone two-part cage had good slip behavior under compression, flexion, extension, lateral bending and torsion, as compared with the other two interbody cages, even with the additional posterior fixation. However, the two-part cage had the lowest rotational angles under flexion and torsion, but had no differences under extension and lateral bending. Conclusion The biomechanical benefit of a stand-alone two-part fusion cage can be justified. This device provided the stability required for interbody fusion, which supports clinical trials of the cage as an alternative to circumferential fixations.

  10. Systematic Multi-variable H-infinity Control Design for Primary Frequency Regulation in Stand-alone Microgrids with High Penetration of Renewable Energy Sources

    Lam , Quang Linh; Bratcu , Antoneta Iuliana; Riu , Delphine

    2016-01-01

    International audience; In this paper, a systematic design of a robust multi-variable control structure for primary frequency regulation in microgrids with high rate of renewable source penetration is proposed. The considered microgrid represents a diesel-photovoltaic-supercapacitor hybrid power generation system operating in stand-alone mode. The proposed control structure relies on a two-level architecture: classical PI-based current tracking controllers are placed on the low control level ...

  11. Agreement of manual cell counts and automated counts of the scil Vet abc Plus(+) hematology analyzer for analysis of equine synovial fluid.

    Van de Water, Eline; Oosterlinck, Maarten; Duchateau, Luc; Pille, Frederik

    2016-06-01

    The purpose of this study was to determine whether the scil Vet abc Plus(+) (SCIL Animal Care Company, Altorf, France), an impedance hematology analyzer, can accurately quantify and differentiate nucleated blood cells (NBCs) in equine synovial fluid. Synovial fluid samples (n=242) in different stages of experimentally induced inflammation were analyzed with and without hyaluronidase pretreatment and compared to manual hemocytometer counts and smear reviews. No significant effect of hyaluronidase pretreatment was observed. Total nucleated cell counts of the scil Vet abc Plus(+) were significantly higher compared to the manual method (P=0.02), yet the difference was small and clinically irrelevant (ratio manual/automated count equal to 0.97 with 95% CI [0.95, 1.00]). Differential cell counts of the scil Vet abc Plus(+) were not accurate. In conclusion, the scil Vet abc Plus(+) hematology analyzer is highly accurate for quantification, but not accurate for differentiation of NBCs in equine synovial fluid. Copyright © 2016 Elsevier Ltd. All rights reserved.

  12. Performance of a small stand alone photovoltaic-wind system at El Oyameyo D.F., Mexico

    Sanchez Juarez, A.; Campos, J. [Centro de Investigacion en Energia, UNAM, Mexico, D. F. (Mexico); Tiburcio Silver, A. [Instituto Tecnologico de Toluca-Division de Posgrado, Toluca (Mexico)

    1997-12-31

    El Oyameyo, is an ecological site located to the South-West of the Topilejo town, D.F., 19 degree 25` North latitude, 99 degree 5` West longitude and at an altitude of 3100 m. At present, there are 10 families living at this place. They have energy generators to produce their own electricity by means of solar or wind energy using photovoltaic (PV) technology and eolic systems, respectively. There are three different configurations of energy generators: DC regulated PV systems, AC regulated PV systems and one PV-Wind hybrid system. The electrical power installed for the stand alone PV systems are from 48 W-p up to 768 W-p range. Among these, there are 4 PV systems that are configurated in DC regulated systems, and other 6 are AC regulated systems. All these systems use lead-acid battery (scaled or vented) banks to store the energy produced daily by the systems. The PV-Wind hybrid system in formed, at present, by a 5.0 kW wind generator, a PV array of 768 W-p, a 37.8 kW-h storage battery bank and a 5.0 kW DC/AC inverter. In this work, we report the electricity generated, load pattern and overall system performance of the photovoltaic-wind hybrid system. The technical characteristics, energy test on the hybrid system and the experience obtained from energy handling and system maintenance for all the systems are presented. We found that all the systems had shown good performance and users` satisfaction. [Espanol] El Oyameyo es un lugar ecologico localizado al Sur-Oeste del pueblo de Topilejo, D. F., 19 grados 25` de latitud Norte 99 grados 5` de longitud Oeste y a una altitud de 3100m. Actualmente hay 10 familias viviendo en este lugar. Tienen generadores de energia para producir su propia electricidad mediante la energia solar y la del viento usando sistemas fotovoltaicos (FV) y sistemas eolicos, respectivamente. Hay tres diferentes configuraciones de generadores de energia: sistemas fotovoltaicos de CD regulados, sistemas fotovoltaicos de CA regulados y un sistema

  13. Design of a small scale stand-alone solar thermal co-generation plant for an isolated region in Egypt

    Abdelhady, Suzan; Borello, Domenico; Tortora, Eileen

    2014-01-01

    Highlights: • In the selected area, connection to the grid is very difficult and expensive. • The integrated unsteady CSP/ORC system, was modeled TRNSYS. • Assuming a CSP of 200,000 m 2 , 6 MW e and 21.5 MW th can be obtained. • The energy is sufficient to feed more than 3,300 rural users and two big factories. • PER = 1.43, LCOE = 1.25 USD/kW h and the GHG emissions are reduced of 7300 toe/year. - Abstract: Most of Egypt’s population is concentrated in the Nile Valley (5% of Egypt’s area), while the western desert occupies an area of 50% of the total area of Egypt with a small number of inhabitants. The New Valley is the largest governorates in Egypt which occupies 45.8% of the total area of the Country and 65% of the Western Desert and it is the least densely populated governorate in Egypt. However, New Valley has started to receive the migrated people from the Nile valley and Delta region and the demand for the energy is continuously increasing. However, the rural area in New Valley still suffers from lack of access to energy services. The very high transmission losses and costs are the main challenges for electrification in this area. Then, it is worth to investigate the opportunities for distributed energy generation. This area of Egypt receives some of the highest solar radiation in the world (up to 3000 kW h per square meters per year), making it a prime location for use of this resource. In this study, performance and economic assessment of a small scale stand-alone solar thermal co-generation plant using diathermic oil is presented. This configuration is considered as a promising and sustainable solution to provide electricity and heat to an isolated area satisfying the local loads. Parabolic trough plant has been modeled in TRNSYS simulation environment integrated with the Solar Thermal Electric Components (STEC) model library. Both solar and power cycle performances have been modeled based on the solar energy data of the plant site. The

  14. Performance of a small stand alone photovoltaic-wind system at El Oyameyo D.F., Mexico

    Sanchez Juarez, A; Campos, J [Centro de Investigacion en Energia, UNAM, Mexico, D. F. (Mexico); Tiburcio Silver, A [Instituto Tecnologico de Toluca-Division de Posgrado, Toluca (Mexico)

    1998-12-31

    El Oyameyo, is an ecological site located to the South-West of the Topilejo town, D.F., 19 degree 25` North latitude, 99 degree 5` West longitude and at an altitude of 3100 m. At present, there are 10 families living at this place. They have energy generators to produce their own electricity by means of solar or wind energy using photovoltaic (PV) technology and eolic systems, respectively. There are three different configurations of energy generators: DC regulated PV systems, AC regulated PV systems and one PV-Wind hybrid system. The electrical power installed for the stand alone PV systems are from 48 W-p up to 768 W-p range. Among these, there are 4 PV systems that are configurated in DC regulated systems, and other 6 are AC regulated systems. All these systems use lead-acid battery (scaled or vented) banks to store the energy produced daily by the systems. The PV-Wind hybrid system in formed, at present, by a 5.0 kW wind generator, a PV array of 768 W-p, a 37.8 kW-h storage battery bank and a 5.0 kW DC/AC inverter. In this work, we report the electricity generated, load pattern and overall system performance of the photovoltaic-wind hybrid system. The technical characteristics, energy test on the hybrid system and the experience obtained from energy handling and system maintenance for all the systems are presented. We found that all the systems had shown good performance and users` satisfaction. [Espanol] El Oyameyo es un lugar ecologico localizado al Sur-Oeste del pueblo de Topilejo, D. F., 19 grados 25` de latitud Norte 99 grados 5` de longitud Oeste y a una altitud de 3100m. Actualmente hay 10 familias viviendo en este lugar. Tienen generadores de energia para producir su propia electricidad mediante la energia solar y la del viento usando sistemas fotovoltaicos (FV) y sistemas eolicos, respectivamente. Hay tres diferentes configuraciones de generadores de energia: sistemas fotovoltaicos de CD regulados, sistemas fotovoltaicos de CA regulados y un sistema

  15. Stand-alone containment analysis of Phébus FPT tests with ASTEC and MELCOR codes: the FPT-2 test.

    Gonfiotti, Bruno; Paci, Sandro

    2018-03-01

    During the last 40 years, many studies have been carried out to investigate the different phenomena occurring during a Severe Accident (SA) in a Nuclear Power Plant (NPP). Such efforts have been supported by the execution of different experimental campaigns, and the integral Phébus FP tests were probably some of the most important experiments in this field. In these tests, the degradation of a Pressurized Water Reactor (PWR) fuel bundle was investigated employing different control rod materials and burn-up levels in strongly or weakly oxidizing conditions. From the findings on these and previous tests, numerical codes such as ASTEC and MELCOR have been developed to analyze the evolution of a SA in real NPPs. After the termination of the Phébus FP campaign, these two codes have been furthermore improved to implement the more recent findings coming from different experimental campaigns. Therefore, continuous verification and validation is still necessary to check that the new improvements introduced in such codes allow also a better prediction of these Phébus tests. The aim of the present work is to re-analyze the Phébus FPT-2 test employing the updated ASTEC and MELCOR code versions. The analysis focuses on the stand-alone containment aspects of this test, and three different spatial nodalizations of the containment vessel (CV) have been developed. The paper summarizes the main thermal-hydraulic results and presents different sensitivity analyses carried out on the aerosols and fission products (FP) behavior. When possible, a comparison among the results obtained during this work and by different authors in previous work is also performed. This paper is part of a series of publications covering the four Phébus FP tests using a PWR fuel bundle: FPT-0, FPT-1, FPT-2, and FPT-3, excluding the FPT-4 one, related to the study of the release of low-volatility FP and transuranic elements from a debris bed and a pool of melted fuel.

  16. Stand-alone containment analysis of Phébus FPT tests with ASTEC and MELCOR codes: the FPT-2 test

    Bruno Gonfiotti

    2018-03-01

    Full Text Available During the last 40 years, many studies have been carried out to investigate the different phenomena occurring during a Severe Accident (SA in a Nuclear Power Plant (NPP. Such efforts have been supported by the execution of different experimental campaigns, and the integral Phébus FP tests were probably some of the most important experiments in this field. In these tests, the degradation of a Pressurized Water Reactor (PWR fuel bundle was investigated employing different control rod materials and burn-up levels in strongly or weakly oxidizing conditions. From the findings on these and previous tests, numerical codes such as ASTEC and MELCOR have been developed to analyze the evolution of a SA in real NPPs. After the termination of the Phébus FP campaign, these two codes have been furthermore improved to implement the more recent findings coming from different experimental campaigns. Therefore, continuous verification and validation is still necessary to check that the new improvements introduced in such codes allow also a better prediction of these Phébus tests. The aim of the present work is to re-analyze the Phébus FPT-2 test employing the updated ASTEC and MELCOR code versions. The analysis focuses on the stand-alone containment aspects of this test, and three different spatial nodalizations of the containment vessel (CV have been developed. The paper summarizes the main thermal-hydraulic results and presents different sensitivity analyses carried out on the aerosols and fission products (FP behavior. When possible, a comparison among the results obtained during this work and by different authors in previous work is also performed. This paper is part of a series of publications covering the four Phébus FP tests using a PWR fuel bundle: FPT-0, FPT-1, FPT-2, and FPT-3, excluding the FPT-4 one, related to the study of the release of low-volatility FP and transuranic elements from a debris bed and a pool of melted fuel. Keywords: Safety

  17. Clinician's perspectives of the relocation of a regional child and adolescent mental health service from co-located to stand alone premises.

    Francis, K J; Boyd, C P; Sewell, J; Nurse, S

    2008-01-01

    Australia's National Mental Health Strategy's statement of rights and responsibilities states that children and adolescents admitted to a mental health facility or community program have the right to be separated from adult patients and provided with programs suited to their developmental needs. However, in rural Australia, where a lack of healthcare services, financial constraints, greater service delivery areas and fewer mental healthcare specialists represent the norm, Child and Adolescent Mental Health Services (CAMHS) are sometimes co-located with adult mental health services. The aim of the present study was to evaluate the impact of a recent relocation of a regional CAMHS in Victoria from co-located to stand alone premises. Six CAMHS clinicians who had experienced service delivery at a co-located setting and the current stand-alone CAMHS setting were interviewed about their perceptions of the impact of the relocation on service delivery. An exploratory interviewing methodology was utilized due to the lack of previous research in this area. Interview data were transcribed and analysed according to interpretative phenomenological analysis techniques. Findings indicated a perception that the relocation was positive for clients due to the family-friendly environment at the new setting and separation of CAMHS from adult psychiatric services. However, the impact of the relocation on clinicians was marked by a perceived loss of social capital from adult psychiatric service clinicians. These results provide increased understanding of the effects of service relocation and the influence of co-located versus stand-alone settings on mental health service delivery - an area where little prior research exists.

  18. [Biomechanicsl evaluation of a stand-alone interbody fusion cage based on porous TiO2/glass-ceramic on the human cervical spine].

    Korinth, M C; Moersch, S; Ragoss, C; Schopphoff, E

    2003-12-01

    Recently, there has been a rapid increase in the use of cervical spine interbody fusion cages, differing in design and biomaterial used, in competition to autologous iliac bone graft and bone cement (PMMA). Limited biomechanical differences in primary stability, as well as advantages and disadvantages of each cage or material have been investigated in studies, using an in vitro human cervical spine model. 20 human cervical spine specimens were tested after fusion with either a cubical stand-alone interbody fusion cage manufactured from a new porous TiO2/glass composite (Ecopore) or PMMA after discectomy. Non-destructive biomechanical testing was performed, including flexion/extension and lateral bending using a spine testing apparatus. Three-dimensional segmental range of motion (ROM) was evaluated using an ultrasound measurement system. ROM increased more in flexion/extension and lateral bending after PMMA fusion (26.5%/36.1%), then after implantation of the Ecopore-cage (8.1%/7.8%). In this first biomechanical in vitro examination of a new porous ceramic bone replacement material a) the feasibility and reproducibility of biomechanical cadaveric cervical examination and its applicability was demonstrated, b) the stability of the ceramic cage as a stand alone interbody cage was confirmed in vitro, and c) basic information and knowledge for our intended biomechanical and histological in vivo testing, after implantation of Ecopore in cervical sheep spines, were obtained.

  19. Risk factors for subsidence in anterior cervical fusion with stand-alone polyetheretherketone (PEEK) cages: a review of 82 cases and 182 levels.

    Kao, Ting-Hsien; Wu, Chen-Hao; Chou, Yu-Ching; Chen, Hsien-Te; Chen, Wen-Hsien; Tsou, Hsi-Kai

    2014-10-01

    To determine risk factors for subsidence in patients treated with anterior cervical discectomy and fusion (ACDF) and stand-alone polyetheretherketone (PEEK) cages. Records of patients with degenerative spondylosis or traumatic disc herniation resulting in radiculopathy or myelopathy between C2 and C7 who underwent ACDF with stand-alone PEEK cages were retrospectively reviewed. Cages were filled with autogenous cancellous bone harvested from iliac crest or hydroxyapatite. Subsidence was defined as a decrease of 3 mm or more of anterior or posterior disc height from that measured on the postoperative radiograph. Eighty-two patients (32 males, 50 females; 182 treatment levels) were included in the analysis. Most patients had 1-2 treatment levels (62.2 %), and 37.8 % had 3-4 treatment levels. Treatment levels were from C2-7. Of the 82 patients, cage subsidence occurred in 31 patients, and at 39 treatment levels. Multivariable analysis showed that subsidence was more likely to occur in patients with more than two treatment levels, and more likely to occur at treatment levels C5-7 than at levels C2-5. Subsidence was not associated with postoperative alignment change but associated with more disc height change (relatively oversized cage). Subsidence is associated with a greater number of treatment levels, treatment at C5-7 and relatively oversized cage use.

  20. DCE-MRI of the breast in a stand-alone setting outside a complementary strategy - results of the TK-study

    Kaiser, Clemens G.; Krammer, J.; Wasser, K.; Schoenberg, S.O. [University Medical Centre Mannheim, Medical Faculty Mannheim-University of Heidelberg, Institute of Clinical Radiology and Nuclear Medicine, Mannheim (Germany); Reich, C.; Kaiser, W.A. [Friedrich-Schiller-University Hospital Jena, Institute of Diagnostic and Interventional Radiology I, Jena (Germany); Dietzel, M. [Friedrich-Alexander-University Hospital Erlangen-Nuernberg, Department of Neuroradiology, Erlangen (Germany); Baltzer, P.A.T. [Medical University Vienna, Institute of Radiology and Nuclear Medicine, Vienna (Austria)

    2015-06-01

    To evaluate the accuracy of MRI of the breast (DCE-MRI) in a stand-alone setting with extended indications. According to the inclusion criteria, breast specialists were invited to refer patients to our institution for DCE-MRI. Depending on the MR findings, patients received either a follow-up or biopsy. Between 04/2006 and 12/2011 a consecutive total of 1,488 women were prospectively examined. Of 1,488 included patients, 393 patients were lost to follow-up, 1,095 patients were evaluated. 124 patients were diagnosed with malignancy by DCE-MRI (76 TP, 48 FP, 971 TN, 0 FN cases). Positive cases were confirmed by histology, negative cases by MR follow-ups or patient questionnaires over the next 5 years in 1,737 cases (sensitivity 100 %; specificity 95.2 %; PPV 61.3 %; NPV 100 %; accuracy 95.5 %). For invasive cancers only (DCIS excluded), the results were 63 TP; 27 FP; 971 TP and 0 FN (sensitivity 100 %; specificity 97.2 %; PPV 70 %; NPV 100 %; accuracy 97.5 %). The DCE-MRI indications tested imply that negative results in DCE-MRI reliably exclude cancer. The results were achieved in a stand-alone setting (single modality diagnosis). However, these results are strongly dependent on reader experience and adequate technical standards as prerequisites for optimal diagnoses. (orig.)

  1. DCE-MRI of the breast in a stand-alone setting outside a complementary strategy - results of the TK-study

    Kaiser, Clemens G.; Krammer, J.; Wasser, K.; Schoenberg, S.O.; Reich, C.; Kaiser, W.A.; Dietzel, M.; Baltzer, P.A.T.

    2015-01-01

    To evaluate the accuracy of MRI of the breast (DCE-MRI) in a stand-alone setting with extended indications. According to the inclusion criteria, breast specialists were invited to refer patients to our institution for DCE-MRI. Depending on the MR findings, patients received either a follow-up or biopsy. Between 04/2006 and 12/2011 a consecutive total of 1,488 women were prospectively examined. Of 1,488 included patients, 393 patients were lost to follow-up, 1,095 patients were evaluated. 124 patients were diagnosed with malignancy by DCE-MRI (76 TP, 48 FP, 971 TN, 0 FN cases). Positive cases were confirmed by histology, negative cases by MR follow-ups or patient questionnaires over the next 5 years in 1,737 cases (sensitivity 100 %; specificity 95.2 %; PPV 61.3 %; NPV 100 %; accuracy 95.5 %). For invasive cancers only (DCIS excluded), the results were 63 TP; 27 FP; 971 TP and 0 FN (sensitivity 100 %; specificity 97.2 %; PPV 70 %; NPV 100 %; accuracy 97.5 %). The DCE-MRI indications tested imply that negative results in DCE-MRI reliably exclude cancer. The results were achieved in a stand-alone setting (single modality diagnosis). However, these results are strongly dependent on reader experience and adequate technical standards as prerequisites for optimal diagnoses. (orig.)

  2. Wireless network of stand-alone end effect probes for soil in situ permittivity measurements over the 100MHZ-6GHz frequency range

    Demontoux, François; Bircher, Simone; Ruffié, Gilles; Bonnaudiin, Fabrice; Wigneron, Jean-Pierre; Kerr, Yann

    2017-04-01

    , it should be useful to install many probes on the same site to obtain permittivity measurements over a large area. To reach this goal, the probes should communicate with each other to send data to a record device. Furthermore, it is needed to record measurements over a long time period (many months) to study the in-situ dielectric soil property variations according to changing weather conditions and seasonal trends. The goal of the research work presented is to develop a dielectric sensor system based on end effect probes able to communicate the data using wireless technology. It must be stand-alone from an electric and data recording point of view so it must integrate a VNA circuit instead of the ANRITSU VNA used for the moment. The LoRa wireless technology has been selected because of its low electric consumption and the large distance between equipment available. LoRaWAN™ is a Low Power Wide Area Network specification intended for wireless battery operated devices. The LoRaWAN data rates range from 0.3 kbps to 50 kbps which is sufficient for our probes' data exchanges. We will present the work done to perform the VNA and the LoRa communication board as well as the work done to improve the probes and the permittivity computation algorithm.

  3. [Evaluation of the analyzer of hematology Beckman Coulter® HmX™ in the university hospital of Oran].

    Zmouli, N; Moulasserdoun, K; Seghier, F

    2013-11-01

    The choice of an automaton of haematology is a determining stage, which has to take into account at the same time the quality of the results and the economic imperatives: workload, structure and organization of the laboratory. [corrected] It is in this spirit that we estimated during a period of 3 months the analyzer of haematology: the HmX™ Coulter with boatman of samples of the company Beckman. This automaton realizes the blood numeration, the formula leukocytic and the reticulocyte count. At first, we estimated the appropriate characteristics of device. Secondly, we estimated the relevance, the sensibility and the specificity of the alarms by comparing with the reference method, which is the optical microscopy. For that purpose, 125 blood smears resulting from service of haematology and from resuscitation were examined in optical microscopy. The technical tests were realized according to the recommendations of the International committee for evaluation of automatons of haematology. The analytical performances were satisfactory in particular the big interval of linearity and the absence of contamination. As regards the evaluation of the alarms system: rate of rejection is 63%, the sensibility 86%, the specificity 70%, the positive predictive value 80%, the negative predictive value 78% and the efficiency 80%. The alarms myelaemia and atypical lymphocytes were never sources of false negatives. The alarms erythroblasts and platelet aggregates did not engendered positive forgery. The blast cell alarm was responsible for a single case of false negative. The faithfulness of automaton is satisfactory: the absence of contamination, the big interval of linearity for the leukocytes, the red blood cells and the platelets as well as a good relevance of the alarms with regard to the anomalies found on the peripheral blood smear. From the user-friendliness and practicability point of view, the HmX™ Coulter was deeply appreciated. Copyright © 2013 Elsevier Masson SAS. All

  4. Factors Influencing the Presence of Ethics and CSR Stand-Alone Courses in the Accounting Masters Curricula: An International Study

    Larrán Jorge, Manuel; Andrades Peña, Francisco Javier; Muriel de los Reyes, María José

    2015-01-01

    This paper provides a web-content analysis of the curriculum and subjects of the top accounting and auditing masters identified in the Eduniversal 2012-2013 ratings of the best business schools in the world. The main aim of this study is to analyze the influence exerted by different factors on the extent to which accounting programs are…

  5. Hematologic emergencies

    Daniele Vallisa

    2012-01-01

    Full Text Available In recent years, the surprising progress made in other areas of hematology (advances in the understanding of leukemogenesis, improved transplant techniques has been conspicuously absent in the management of hematologic emergencies. And yet, every step toward greater knowledge, every new treatment option will be of little value unless we are able to manage the acute complications of hematologic diseases. These complications are better defined as hematologic emergencies, and they are characterized by a high rate of mortality. This review is based on a search of the literature that was initially confined to articles published in the journal Hematology from 2000 to 2009. The search was then extended to the Cochrane Library and to Pub Med in February 2010 with the following Keywords emergencies; urgencies; hematology. The same key words were employed in a search of the archives of Blood and the New England Journal of Medicine from 2000 to 2010. The results confirm that hematologic emergencies can be caused by hematologic malignancies as well as by non-neoplastic hematologic diseases. Within the former category; this review examines the causes; manifestations; treatment and prevention of disseminated intravascular coagulation; superior vena caval syndrome; spinal cord compression; tumor lysis syndrome; hyperleukocytosis; and hypercalcemia. We also review emergency situations associated with non-neoplatic haematological diseases; such as thrombotic thrombocytopenic purpura; drug-induced hemolytic anemia; and acute sickle-cell crisis.

  6. Techno-economic assessment of FT unit for synthetic diesel production in existing stand-alone biomass gasification plant using process simulation tool

    Hunpinyo, Piyapong; Narataruksa, Phavanee; Tungkamani, Sabaithip

    2014-01-01

    For alternative thermo-chemical conversion process route via gasification, biomass can be gasified to produce syngas (mainly CO and H2). On more applications of utilization, syngas can be used to synthesize fuels through the catalytic process option for producing synthetic liquid fuels...... such as Fischer-Tropsch (FT) diesel. The embedding of the FT plant into the stand-alone based on power mode plants for production of a synthetic fuel is a promising practice, which requires an extensive adaptation of conventional techniques to the special chemical needs found in a gasified biomass. Because...... there are currently no plans to engage the FT process in Thailand, the authors have targeted that this work focus on improving the FT configurations in existing biomass gasification facilities (10 MWth). A process simulation model for calculating extended unit operations in a demonstrative context is designed...

  7. Effect of State Feedback Coupling and System Delays on the Transient Performance of Stand-Alone VSI with LC Output Filter

    Federico, de Bosio; de Sousa Ribeiro, Luiz Antonio; Freijedo Fernandez, Francisco Daniel

    2016-01-01

    The influence of state feedback coupling in the dynamics performance of power converters for stand-alone microgrids is investigated. Computation and PWM delays are the main factors that limit the achievable bandwidth of current regulators in digital implementations. In particular, the performance...... of state feedback decoupling is degraded because of these delays. Two decoupling techniques to improve the transient response of the system are investigated, named non-ideal and ideal capacitor voltage decoupling respectively. In particular, the latter solution consists in leading the capacitor voltage...... on the state feedback decoupling path in order to compensate for system delays. Practical implementation issues are discussed with reference to both the decoupling techniques. A design methodology for the voltage loop, that considers the closed loop transfer functions developed for the inner loop, is also...

  8. Synchronized Pulsed dc - dc Converter as Maximum Power Position Tracker with Wide Load and Insolation Variation for Stand Alone PV System

    Hardik, P. Desai; Ranjan Maheshwari

    2011-01-01

    This paper investigates the interest focused on employing parallel connected dc-dc converter with high tracking effectiveness under wide variation in environmental conditions (Insolation) and wide load variation. dc-dc converter is an essential part of the stand alone PV system. Paper also presents an approach on how duty cycle for maximum power position (MPP) is adjusted by taking care of varying load conditions and without iterative steps. Synchronized PWM pulses are employed for the converter. High tracking efficiency is achieved with continuous input and inductor current. In this approach, the converter can he utilized in buck as well in boost mode. The PV system simulation was verified and experimental results were in agreement to the presented scheme. (authors)

  9. Effects of ozone as a stand-alone and coagulation-aid treatment on the reduction of trihalomethanes precursors from high DOC and hardness water.

    Sadrnourmohamadi, Mehrnaz; Gorczyca, Beata

    2015-04-15

    This study investigates the effect of ozone as a stand-alone and coagulation aid on the removal of dissolved organic carbon (DOC) from the water with a high level of DOC (13.8 mgL(-1)) and calcium hardness (270 mgL(-1)) CaCO3. Natural water collected from the Assiniboine River (Manitoba, Canada) was used in this study. Effectiveness of ozone treatment was evaluated by measurement of DOC, DOC fractions, UV254, and trihalomethane formation potential (THMFP). Additionally, zeta potential and dissolved calcium concentration were measured to discern the mechanism of ozone reactions. Results indicated that 0.8 mg O3/mg DOC ozone stand-alone can cause up to 86% UV254 reduction and up to 27% DOC reduction. DOC fractionation results showed that ozone can change the composition of DOC in the water samples, converting the hydrophobic fractions into hydrophilic ones and resulting in the reduction of THMFP. Also, ozone caused a decrease in particle stability and dissolved calcium concentration. These simultaneous ozonation effects caused improved water flocculation and enhanced removal of DOC. This resulted in reduction of the coagulant dosage when ozone doses higher than 0.2 mg O3/mg DOC were applied prior to coagulation with ferric sulfate. Also, pre-ozonation-coagulation process achieved preferential THMFP removal for all of the ozone doses tested (0-0.8 mg O3/mg DOC), leading to a lower specific THMFP in pre-ozonated-coagulated waters than in the corresponding ozonated waters. Copyright © 2015 Elsevier Ltd. All rights reserved.

  10. Comparison of plate-cage construct and stand-alone anchored spacer in the surgical treatment of three-level cervical spondylotic myelopathy: a preliminary clinical study.

    Shi, Sheng; Liu, Zu-De; Li, Xin-Feng; Qian, Lie; Zhong, Gui-Bin; Chen, Fang-Jing

    2015-09-01

    Although stand-alone cages were advocated to be superior to plate-cage construct (PCC) because of comparable clinical outcomes and fewer plate-related complications, cage dislocation and subsidence were frequently mentioned in multilevel fusion. There are some concerns about whether these issues can be effectively prevented in multilevel anterior cervical discectomy and fusion (ACDF) by stand-alone anchored spacer (SAAS). The aim was to compare clinical outcomes, radiologic parameters, and complications of PCC and SAAS in the treatment of three-level cervical spondylotic myelopathy (CSM). This was a retrospective comparative study. A total of 38 consecutive patients with three-level CSM (ACDF with PCC, 20 patients; ACDF with SAAS, 18 patients) were reviewed. Clinical outcomes were assessed using Japanese Orthopaedic Association and Neck Disability Index. The radiologic evaluations included cervical alignment (CA), segmental angle (SA), postoperative curvature loss (PCL), and incidence of subsidence. All the aforementioned parameters were compared before and after surgery between two groups. Besides, the aforementioned results were also compared between the two groups. The complications were also recorded. The mean follow-up period was 30.3 months. No significant differences were observed in clinical outcomes between the two groups (p>.05). Additionally, no significant differences existed in fusion rate between the two groups. There were significant differences in PCL of SA and CA and correction of SA between the two groups (pSAAS group, and the potential of SAAS to reduce the incidence of postoperative dysphagia was not proven. No other complications were observed in this study. In the surgical treatment of three-level CSM, PCC is superior to SAAS in correction and maintenance of SA and avoiding cage subsidence, although the technique of ACDF with SAAS yielded encouraging clinical outcomes and high fusion rate. Copyright © 2015 Elsevier Inc. All rights reserved.

  11. PR2ALIGN: a stand-alone software program and a web-server for protein sequence alignment using weighted biochemical properties of amino acids.

    Kuznetsov, Igor B; McDuffie, Michael

    2015-05-07

    Alignment of amino acid sequences is the main sequence comparison method used in computational molecular biology. The selection of the amino acid substitution matrix best suitable for a given alignment problem is one of the most important decisions the user has to make. In a conventional amino acid substitution matrix all elements are fixed and their values cannot be easily adjusted. Moreover, most existing amino acid substitution matrices account for the average (dis)similarities between amino acid types and do not distinguish the contribution of a specific biochemical property to these (dis)similarities. PR2ALIGN is a stand-alone software program and a web-server that provide the functionality for implementing flexible user-specified alignment scoring functions and aligning pairs of amino acid sequences based on the comparison of the profiles of biochemical properties of these sequences. Unlike the conventional sequence alignment methods that use 20x20 fixed amino acid substitution matrices, PR2ALIGN uses a set of weighted biochemical properties of amino acids to measure the distance between pairs of aligned residues and to find an optimal minimal distance global alignment. The user can provide any number of amino acid properties and specify a weight for each property. The higher the weight for a given property, the more this property affects the final alignment. We show that in many cases the approach implemented in PR2ALIGN produces better quality pair-wise alignments than the conventional matrix-based approach. PR2ALIGN will be helpful for researchers who wish to align amino acid sequences by using flexible user-specified alignment scoring functions based on the biochemical properties of amino acids instead of the amino acid substitution matrix. To the best of the authors' knowledge, there are no existing stand-alone software programs or web-servers analogous to PR2ALIGN. The software is freely available from http://pr2align.rit.albany.edu.

  12. Real-Time Detection of Tsunami Ionospheric Disturbances with a Stand-Alone GNSS Receiver: A Preliminary Feasibility Demonstration

    Savastano, Giorgio; Komjathy, Attila; Verkhoglyadova, Olga; Mazzoni, Augusto; Crespi, Mattia; Wei, Yong; Mannucci, Anthony J.

    2017-04-01

    It is well known that tsunamis can produce gravity waves that propagate up to the ionosphere generating disturbed electron densities in the E and F regions. These ionospheric disturbances can be studied in detail using ionospheric total electron content (TEC) measurements collected by continuously operating ground-based receivers from the Global Navigation Satellite Systems (GNSS). Here, we present results using a new approach, named VARION (Variometric Approach for Real-Time Ionosphere Observation), and estimate slant TEC (sTEC) variations in a real-time scenario. Using the VARION algorithm we compute TEC variations at 56 GPS receivers in Hawaii as induced by the 2012 Haida Gwaii tsunami event. We observe TEC perturbations with amplitudes of up to 0.25 TEC units and traveling ionospheric perturbations (TIDs) moving away from the earthquake epicenter at an approximate speed of 316 m/s. We perform a wavelet analysis to analyze localized variations of power in the TEC time series and we find perturbation periods consistent with a tsunami typical deep ocean period. Finally, we present comparisons with the real-time tsunami MOST (Method of Splitting Tsunami) model produced by the NOAA Center for Tsunami Research and we observe variations in TEC that correlate in time and space with the tsunami waves.

  13. A qualitative study of how patients with type 2 diabetes use an electronic stand-alone personal health record.

    Fuji, Kevin T; Abbott, Amy A; Galt, Kimberly A

    2015-04-01

    Patient use of personal health records (PHRs) to manage their health information has been proposed to enhance patient knowledge and empower patients to make changes in their self-care behaviors. However, there remains a gap in understanding about patients' actual PHR use behaviors. The purpose of this qualitative study was to explore how patients with type 2 diabetes used a PHR to manage their diabetes-related health information for self-care. Fifty-nine patients with type 2 diabetes were interviewed 3-6 months after receiving initial training on a free-of-charge, Web-based PHR. Interviews were audio-recorded, transcribed, and analyzed using an iterative process of in vivo coding, categorization, and theme development. Nine themes emerged, three of which expressed positive experiences: complete and accessible record; increased awareness; and behavioral changes. The remaining six themes expressed negative experiences: out of sight, out of mind; I would have used it if I were sicker; economic, infrastructure, and computer literacy barriers; lack of patient-provider engagement; double tracking; and privacy and security concerns. Despite some potential positive benefits resulting from PHR use, several barriers inhibited sustained and effective use over time. Provider and patient education about the benefits of PHR use and about the potential for filling in information gaps in the provider-based record is key to engage patients and stimulate PHR adoption and use.

  14. A feasibility study of a stand-alone hybrid solar–wind–battery system for a remote island

    Ma, Tao; Yang, Hongxing; Lu, Lin

    2014-01-01

    Highlights: • A feasibility study of a hybrid solar–wind–battery system is carried out. • Techno-economic evaluation is conducted for this proposed system. • Thousands of cases are simulated to achieve an optimal system configuration. • The performance of the proposed system is analyzed in detail. • A sensitivity analysis on its load and renewable energy resource is performed. - Abstract: This paper presents a detailed feasibility study and techno-economic evaluation of a standalone hybrid solar–wind system with battery energy storage for a remote island. The solar radiation and wind data on this island in 2009 was recorded for this study. The HOMER software was employed to do the simulations and perform the techno-economic evaluation. Thousands of cases have been carried out to achieve an optimal autonomous system configuration, in terms of system net present cost (NPC) and cost of energy (COE). A detailed analysis, description and expected performance of the proposed system were presented. Moreover, the effects of the PV panel sizing, wind turbine sizing and battery bank capacity on the system’s reliability and economic performance were examined. Finally, a sensitivity analysis on its load consumption and renewable energy resource was performed to evaluate the robustness of economic analysis and identify which variable has the greatest impact on the results. The results demonstrate the techno-economic feasibility of implementing the solar–wind–battery system to supply power to this island

  15. Planning tool for least cost system design based on the operating experience of fifty stand-alone photovoltaic hybrid systems

    Bopp, G.; Neufeld, R.; Preiser, K.; Puls, H.-G.; Sauer, D.U.; Senft, S.; Schulz, M. [Fraunhofer Inst. for Solar Energy Systems ISE, Freiburg (Germany)

    2001-07-01

    The Fraunhofer Institute for Solar Energy (ISE) conducted a project involving the design and installation of grid-independent photovoltaic systems with battery storage to 30 remote lodges, mountain huts, farms and private houses. More than half the participating dwellings belonged to the German Alpine Club and are used only for summer months. The photovoltaic systems ranged from lighting for unattended huts and larger systems for lodges with permanent staff and an electricity demand in the order of 0.1 to 40 kWh per day. The objective of the project was to determine the amount of maintenance work that is required to keep the systems working reliably. The Institute prepared inspection manuals and carried out some sample inspections. Other inspections were carried out by the independent operator. With the information entered into the inspection manuals, Fraunhofer ISE analyzed the causes of faults and prepared statistics on interruptions to operations. The average probability of breakdowns could then be determined along with the requirements for optimizing individual components and the entire system. Besides the solar generator, most components of a photovoltaic system with battery storage require repairs, post-installation improvements, regular maintenance or replacement of batteries at intervals of 5 to 10 years. At the end of two years of regular maintenance, the fault rates were reduced from 3 to 1. The Institute also developed the Technical and Least Cost Optimisation (TALCO) tool to calculate the lifetime costs of remote area power supply systems. TALCO describes the electrical characteristics of various components under operating conditions. All economic factors linked to the components are considered. The optimisation algorithm presents the minimum lifetime costs for a given energy demand at specific locations under given boundary conditions. Analytical results showed that PV-hybrid systems are the most cost effective solution for most system applications

  16. Decentralized/stand-alone hybrid Wind-Diesel power systems to meet residential loads of hot coastal regions

    Elhadidy, M.A.; Shaahid, S.M.

    2005-01-01

    In view of rising costs, pollution and fears of exhaustion of oil and coal, governments around the world are encouraging to seek energy from renewable/sustainable energy sources such as wind. The utilization of energy from wind (since the oil embargo of the 1970s) is being widely disseminated for displacement of fossil fuel produced energy and to reduce atmospheric degradation. A system that consists of a wind turbine and Diesel genset is called a Wind-Diesel power system.The literature indicates that the commercial/residential buildings in Saudi Arabia consume an estimated 10-40% of the total electric energy generated. In the present study, the hourly mean wind-speed data of the period 1986-1997 recorded at the solar radiation and meteorological station, Dhahran (26 deg. 32'N, 50 deg. 13'E in the Eastern Coastal Region of Saudi Arabia), has been analyzed to investigate the potential of utilizing hybrid (Wind-Diesel) energy conversion systems to meet the load requirements of a hundred typical two bedroom residential buildings (with annual electrical energy demand of 3512 MWh). The long term monthly average wind speeds for Dhahran range from 4.2 to 6.4 m/s. The hybrid systems considered in the present case study consist of different combinations/clusters of 150 kW commercial wind machines supplemented with battery storage and Diesel back-up. The deficit energy generated by the Diesel generator (for different battery capacities) and the number of operational hours of the Diesel system to meet a specific annual electrical energy demand of 3512 MWh have also been presented. The evaluation of the hybrid system shows that with seven 150 kW wind energy conversion system (WECS) and one day of battery storage, the Diesel back-up system has to provide 21.6% of the load demand. Furthermore, with three days of battery storage, the Diesel back-up system has to provide 17.5% of the load demand. However, in the absence of battery storage, about 37% of the load needs to be

  17. REPTILE HEMATOLOGY

    Nejra Hadžimusić

    2013-03-01

    Full Text Available Determination of the number of circulating blood cells is of a great importance in clinical diagnosis. However, in some species, such as birds and reptiles, it is not possible to determine the number of individual blood cells using standard automated equipment, because of the specific morphological characteristics. For this reason, recognition of individual cell elements is crucial during hematological examination. Key words: Hematology, reptiles, blood cell morphology

  18. A practical multi-objective design approach for optimum exhaust heat recovery from hybrid stand-alone PV-diesel power systems

    Yousefi, Moslem; Kim, Joong Hoon; Hooshyar, Danial; Yousefi, Milad; Sahari, Khairul Salleh Mohamed; Ahmad, Rodina Binti

    2017-01-01

    Highlights: • Heat recovery exchanger is designed based on practical conditions of a hybrid power system. • Off-the-grid electricity system modeling and analysis using micro-grid analysis software HOMER. • NSGA-II is used for the multi-objective design optimization task. • A new local search is proposed to incorporate the engineering knowledge in NSGA-II. • The proposed approach outperforms the existing ones. - Abstract: Integration of solar power and diesel generators (DGs) together with battery storage has proven to be an efficient choice for stand-alone power systems (SAPS). For higher energy efficiency, heat recovery from exhaust gas of the DG can also be employed to supply all or a portion of the thermal energy demand. Although the design of such heat recovery systems (HRSs) has been studied, the effect of solar power integration has not been taken into account. In this paper, a new approach for practical design of these systems based on varying engine loads is presented. Fast and elitist non-dominated sorting genetic algorithm (NSGA-II) equipped with a novel local search was used for the design process, considering conflicting objectives of annual energy recovery and total cost of the system, and six design variables. An integrated power system, designed for a remote SAPS, was used to evaluate the design approach. The optimum power supply system was first designed using the commercial software Hybrid Optimization of Multiple Energy Resources (HOMER), based on power demand and global solar energy in the region. Heat recovery design was based on the outcome of HOMER for DG hourly load, considering different power scenarios. The proposed approach improves the annual heat recovery of the PV/DG/battery system by 4%, PV/battery by 1.7%, and stand-alone DG by 1.8% when compared with a conventional design based on nominal DG load. The results prove that the proposed approach is effective and that load calculations should be taken into account prior to

  19. Optimal Sizing of a Stand-Alone Hybrid Power System Based on Battery/Hydrogen with an Improved Ant Colony Optimization

    Weiqiang Dong

    2016-09-01

    Full Text Available A distributed power system with renewable energy sources is very popular in recent years due to the rapid depletion of conventional sources of energy. Reasonable sizing for such power systems could improve the power supply reliability and reduce the annual system cost. The goal of this work is to optimize the size of a stand-alone hybrid photovoltaic (PV/wind turbine (WT/battery (B/hydrogen system (a hybrid system based on battery and hydrogen (HS-BH for reliable and economic supply. Two objectives that take the minimum annual system cost and maximum system reliability described as the loss of power supply probability (LPSP have been addressed for sizing HS-BH from a more comprehensive perspective, considering the basic demand of load, the profit from hydrogen, which is produced by HS-BH, and an effective energy storage strategy. An improved ant colony optimization (ACO algorithm has been presented to solve the sizing problem of HS-BH. Finally, a simulation experiment has been done to demonstrate the developed results, in which some comparisons have been done to emphasize the advantage of HS-BH with the aid of data from an island of Zhejiang, China.

  20. Stand-Alone Containment Analysis of the Phébus FPT Tests with the ASTEC and the MELCOR Codes: The FPT-0 Test

    Bruno Gonfiotti

    2017-01-01

    Full Text Available The integral Phébus tests were probably one of the most important experimental campaigns performed to investigate the progression of severe accidents in light water reactors. In these tests, the degradation of a PWR fuel bundle was investigated employing different control rod materials and burn-up levels in strongly or weakly oxidizing conditions. From the results of such tests, numerical codes such as ASTEC and MELCOR have been developed to describe the evolution of a severe accident. After the termination of the experimental Phébus campaign, these two codes were furthermore expanded. Therefore, the aim of the present work is to reanalyze the first Phébus test (FPT-0 employing the updated ASTEC and MELCOR versions to ensure that the new improvements introduced in such codes allow also a better prediction of these Phébus tests. The analysis focuses on the stand-alone containment aspects of this test, and the paper summarizes the main thermal-hydraulic results and presents different sensitivity analyses carried out on the aerosols and fission products behavior. This paper is part of a series of publications covering the four executed Phébus tests employing a solid PWR fuel bundle: FPT-0, FPT-1, FPT-2, and FPT-3.

  1. Methodology for predicting sequences of mean monthly clearness index and daily solar radiation data in remote areas: Application for sizing a stand-alone PV system

    Mellit, A. [Department of Electronics, Institute of Sciences Engineering, Centre University of Medea, Medea 26000 (Algeria); Department of Electronics, Faculty of Science Engineering, Blida University, Blida 09000 (Algeria); Kalogirou, S.A. [Higher Technical Institute, P.O. Box 20423, Nicosia 2152 (Cyprus); Shaari, S. [Faculty of Applied Sciences, Universiti Teknologi MARA 40450 Shah Alam, Selangor (Malaysia); Salhi, H. [Department of Electronics, Faculty of Science Engineering, Blida University, Blida 09000 (Algeria); Hadj Arab, A. [Development Centre of Renewable Energy (CDER), P.O. Box 62, Bouzareah, Algiers 16000 (Algeria); Departamento de Energias Renerables, CIEMAT, Arda Complutense, 22, Madrid 28040 (Spain)

    2008-07-15

    In this paper, a suitable adaptive neuro-fuzzy inference system (ANFIS) model is presented for estimating sequences of mean monthly clearness index (anti K{sub t}) and total solar radiation data in isolated sites based on geographical coordinates. The magnitude of solar radiation is the most important parameter for sizing photovoltaic (PV) systems. The ANFIS model is trained by using a multi-layer perceptron (MLP) based on fuzzy logic (FL) rules. The inputs of the ANFIS are the latitude, longitude, and altitude, while the outputs are the 12-values of mean monthly clearness index anti K{sub t}. These data have been collected from 60 locations in Algeria. The results show that the performance of the proposed approach in the prediction of mean monthly clearness index anti K{sub t} is favorably compared to the measured values. The root mean square error (RMSE) between measured and estimated values varies between 0.0215 and 0.0235 and the mean absolute percentage error (MAPE) is less than 2.2%. In addition, a comparison between the results obtained by the ANFIS model and artificial neural network (ANN) models, is presented in order to show the advantage of the proposed method. An example for sizing a stand-alone PV system is also presented. This technique has been applied to Algerian locations, but it can be generalized for any geographical position. It can also be used for estimating other meteorological parameters such as temperature, humidity and wind speed. (author)

  2. A case study of a typical 2.32 kW{sub P} stand-alone photovoltaic (SAPV) in composite climate of New Delhi (India)

    Chel, Arvind; Tiwari, G.N. [Center for Energy Studies (CES), Indian Institute of Technology, Hauz Khas, New Delhi 110 016 (India)

    2011-04-15

    This paper presents rigorous experimental outdoor performance of a 2.32 kW{sub P} stand-alone photovoltaic (SAPV) system in New Delhi (India) for four weather types in each month such as clear, hazy, partially cloudy/foggy and fully cloudy/foggy weather conditions respectively. The daily power generated from the existing SAPV system was experimentally found in the range of 4-6 kW h/day depending on the prevailing sky conditions. The number of days and daily power generated corresponding to four weather types in each month were used to determine monthly and subsequently annual power generation from the existing SAPV system. There are three daily load profiles with and without earth to air heat exchanger suitable for three seasons like summer (3.75-6.15 kW h/day), winter (2.79-5.19 kW h/day) and rainy (3.75 kW h/day). The hourly efficiency of the SAPV system components are determined and presented in this paper. The life cycle cost (LCC) analysis for the existing typical SAPV system is carried out to determine unit cost of electricity. The effect of annual degradation rate of PV system efficiency is also presented in this paper. The energy production factor (EPF) and the energy payback time (EPBT) of the SAPV system was also determined and presented in this paper. (author)

  3. CRionScan: A stand-alone real time controller designed to perform ion beam imaging, dose controlled irradiation and proton beam writing

    Daudin, L.; Barberet, Ph.; Serani, L.; Moretto, Ph.

    2013-07-01

    High resolution ion microbeams, usually used to perform elemental mapping, low dose targeted irradiation or ion beam lithography needs a very flexible beam control system. For this purpose, we have developed a dedicated system (called “CRionScan”), on the AIFIRA facility (Applications Interdisciplinaires des Faisceaux d'Ions en Région Aquitaine). It consists of a stand-alone real-time scanning and imaging instrument based on a Compact Reconfigurable Input/Output (Compact RIO) device from National Instruments™. It is based on a real-time controller, a Field Programmable Gate Array (FPGA), input/output modules and Ethernet connectivity. We have implemented a fast and deterministic beam scanning system interfaced with our commercial data acquisition system without any hardware development. CRionScan is built under LabVIEW™ and has been used on AIFIRA's nanobeam line since 2009 (Barberet et al., 2009, 2011) [1,2]. A Graphical User Interface (GUI) embedded in the Compact RIO as a web page is used to control the scanning parameters. In addition, a fast electrostatic beam blanking trigger has been included in the FPGA and high speed counters (15 MHz) have been implemented to perform dose controlled irradiation and on-line images on the GUI. Analog to Digital converters are used for the beam current measurement and in the near future for secondary electrons imaging. Other functionalities have been integrated in this controller like LED lighting using Pulse Width Modulation and a “NIM Wilkinson ADC” data acquisition.

  4. CRionScan: A stand-alone real time controller designed to perform ion beam imaging, dose controlled irradiation and proton beam writing

    Daudin, L., E-mail: daudin@cenbg.in2p3.fr [Université Bordeaux, CENBG, UMR 5797, F-33170 Gradignan (France); CNRS, IN2P3, CENBG, UMR 5797, F-33170 Gradignan (France); Barberet, Ph.; Serani, L.; Moretto, Ph. [Université Bordeaux, CENBG, UMR 5797, F-33170 Gradignan (France); CNRS, IN2P3, CENBG, UMR 5797, F-33170 Gradignan (France)

    2013-07-01

    High resolution ion microbeams, usually used to perform elemental mapping, low dose targeted irradiation or ion beam lithography needs a very flexible beam control system. For this purpose, we have developed a dedicated system (called “CRionScan”), on the AIFIRA facility (Applications Interdisciplinaires des Faisceaux d’Ions en Région Aquitaine). It consists of a stand-alone real-time scanning and imaging instrument based on a Compact Reconfigurable Input/Output (Compact RIO) device from National Instruments™. It is based on a real-time controller, a Field Programmable Gate Array (FPGA), input/output modules and Ethernet connectivity. We have implemented a fast and deterministic beam scanning system interfaced with our commercial data acquisition system without any hardware development. CRionScan is built under LabVIEW™ and has been used on AIFIRA’s nanobeam line since 2009 (Barberet et al., 2009, 2011) [1,2]. A Graphical User Interface (GUI) embedded in the Compact RIO as a web page is used to control the scanning parameters. In addition, a fast electrostatic beam blanking trigger has been included in the FPGA and high speed counters (15 MHz) have been implemented to perform dose controlled irradiation and on-line images on the GUI. Analog to Digital converters are used for the beam current measurement and in the near future for secondary electrons imaging. Other functionalities have been integrated in this controller like LED lighting using Pulse Width Modulation and a “NIM Wilkinson ADC” data acquisition.

  5. Stand-alone photovoltaic (PV) integrated with earth to air heat exchanger (EAHE) for space heating/cooling of adobe house in New Delhi (India)

    Chel, Arvind; Tiwari, G.N.

    2010-01-01

    This paper deals with an experimental outdoor annual performance evaluation of 2.32 kW P photovoltaic (PV) power system located at solar energy park in New Delhi composite climatic conditions. This PV system operates the daily electrical load nearly 10 kW h/day which comprises of various applications such as electric air blower of an earth to air heat exchanger (EAHE) used for heating/cooling of adobe house, ceiling fan, fluorescent tube-light, computer, submersible water pump, etc. The outdoor efficiencies, power generated and lost in PV system components were determined using hourly experimental measured data for 1 year on typical clear day in each month. These realistic data are useful for design engineers for outdoor assessment of PV system components. The energy conservation, mitigation of CO 2 emission and carbon credit potential of the existing PV integrated EAHE system is presented in this paper. Also, the energy payback time (EPBT) and unit cost of electricity were determined for both stand-alone PV (SAPV) and building roof integrated PV (BIPV) systems.

  6. Reptile Hematology.

    Sykes, John M; Klaphake, Eric

    2015-09-01

    The basic principles of hematology used in mammalian medicine can be applied to reptiles. The appearances of the blood cells are significantly different from those seen in most mammals, and vary with taxa and staining method used. Many causes for abnormalities of the reptilian hemogram are similar to those for mammals, although additional factors such as venipuncture site, season, hibernation status, captivity status, and environmental factors can also affect values, making interpretation of hematologic results challenging. Values in an individual should be compared with reference ranges specific to that species, gender, and environmental conditions when available. Copyright © 2015 Elsevier Inc. All rights reserved.

  7. The international phase 4 validation study of the EORTC QLQ-SWB32: A stand-alone measure of spiritual well-being for people receiving palliative care for cancer

    Vivat, B.; Young, T. E.; Winstanley, J.; Arraras, J. I.; Black, K.; Boyle, F.; Bredart, A.; Costantini, A.; Guo, J.; Irarrazaval, M. E.; Kobayashi, K.; Kruizinga, R.; Navarro, M.; Omidvari, S.; Rohde, G. E.; Serpentini, S.; Spry, N.; van Laarhoven, H. W. M.; Yang, G. M.

    2017-01-01

    The EORTC Quality of Life Group has just completed the final phase (field-testing and validation) of an international project to develop a stand-alone measure of spiritual well-being (SWB) for palliative cancer patients. Participants (n = 451)-from 14 countries on four continents; 54% female; 188

  8. The Impact of Course Delivery Systems on Student Achievement and Sense of Community: A Comparison of Learning Community versus Stand-Alone Classroom Settings in an Open-Enrollment Inner City Public Community College

    Bandyopadhyay, Pamela

    2010-01-01

    This study examined the effects of two types of course delivery systems (learning community classroom environments versus stand-alone classroom environments) on the achievement of students who were simultaneously enrolled in remedial and college-level social science courses at an inner city open-enrollment public community college. This study was…

  9. Hydrogen-based energy storage unit for stand alone PV systems; L'hydrogene electrolytique comme moyen de stockage d'electricite pour systemes photovoltaiques isoles

    Labbe, J

    2006-12-15

    Stand alone systems supplied only by a photovoltaic generator need an energy storage unit to be fully self sufficient. Lead acid batteries are commonly used to store energy because of their low cost, despite several operational constraints. A hydrogen-based energy storage unit (HESU) could be another candidate, including an electrolyser, a fuel cell and a hydrogen tank. However many efforts still need to be carried out for this technology to reach an industrial stage. In particular, market outlets must be clearly identified. The study of small stationary applications (few kW) is performed by numerical simulations. A simulator is developed in the Matlab/Simulink environment. It is mainly composed of a photovoltaic field and a storage unit (lead acid batteries, HESU, or hybrid storage HESU/batteries). The system component sizing is achieved in order to ensure the complete system autonomy over a whole year of operation. The simulator is tested with 160 load profiles (1 kW as a yearly mean value) and three locations (Algeria, France and Norway). Two coefficients are set in order to quantify the correlation between the power consumption of the end user and the renewable resource availability at both daily and yearly scales. Among the tested cases, a limit value of the yearly correlation coefficient came out, enabling to recommend the use of the most adapted storage to a considered case. There are cases for which using HESU instead of lead acid batteries can increase the system efficiency, decrease the size of the photovoltaic field and improve the exploitation of the renewable resource. In addition, hybridization of HESU with batteries always leads to system enhancements regarding its sizing and performance, with an efficiency increase by 10 to 40 % depending on the considered location. The good agreement between the simulation data and field data gathered on real systems enabled the validation of the models used in this study. (author)

  10. Further development of LLNA:DAE method as stand-alone skin-sensitization testing method and applied for evaluation of relative skin-sensitizing potency between chemicals.

    Yamashita, Kunihiko; Shinoda, Shinsuke; Hagiwara, Saori; Itagaki, Hiroshi

    2015-04-01

    To date, there has been no well-established local lymph node assay (LLNA) that includes an elicitation phase. Therefore, we developed a modified local lymph node assay with an elicitation phase (LLNA:DAE) to discriminate true skin sensitizers from chemicals that gave borderline positive results and previously reported this assay. To develop the LLNA:DAE method as a useful stand-alone testing method, we investigated the complete procedure for the LLNA:DAE method using hexyl cinnamic aldehyde (HCA), isoeugenol, and 2,4-dinitrochlorobenzene (DNCB) as test compounds. We defined the LLNA:DAE procedure as follows: in the dose-finding test, four concentrations of chemical applied to dorsum of the right ear on days 1, 2, and 3 and dorsum of both ears on day 10. Ear thickness and skin irritation score were measured on days 1, 3, 5, 10, and 12. Local lymph nodes were excised and weighed on day 12. The test dose for the primary LLNA:DAE study was selected as the dose that gave the highest left ear lymph node weight in the dose-finding study, or the lowest dose that produced a left ear lymph node of over 4 mg. This procedure was validated using nine different chemicals. Furthermore, qualitative relationship was observed between the degree of elicitation response in the left ear lymph node and the skin sensitizing potency of 32 chemicals tested in this study and the previous study. These results indicated that LLNA:DAE method was as first LLNA method that was able to evaluate the skin sensitizing potential and potency in elicitation response.

  11. Radiation hematology

    Zherbin, E.A.; Chukhlovin, A.B.

    1989-01-01

    State-of-the-Art ofl radiation hematology and review of the problems now facing this brauch of radiobiology and nuclear medicine are presented. Distortion of division and maturation of hemopoiesis parent cells is considered as main factor of radiopathology for hematopoetic system. Problems of radiation injury and functional variation of hematopoetic microenvironment cell populations are discussed. 176 figs.; 23 figs.; 18 tabs

  12. Comparison study of the rates of manual peripheral blood smear review from 3 automated hematology analyzers, Unicel DxH 800, ADVIA 2120i, and XE 2100, using international consensus group guidelines.

    Kim, Sue Jung; Kim, Yoonjung; Shin, Saeam; Song, Jaewoo; Choi, Jong Rak

    2012-11-01

    In the clinical laboratory, it is important both to reduce the number of peripheral blood slide reviews to save time and money and to avoid reporting false results. To determine differences in the slide review rates of 3 widely used automated hematologic analyzers, the Unicel DxH 800 (Beckman Coulter Inc, Fullerton, California), ADVIA 2120i (Siemens Diagnostics, Tarrytown, New York), and XE 2100 (Sysmex, Kobe, Japan), using International Consensus Group for Hematology Review guidelines. A total of 1485 samples were tested, and 300 were manually reviewed. Slide review rates, sensitivity, specificity, and false-positive and false-negative rates were estimated using consensus group rules and compared using χ(2) tests, Fisher exact tests, or generalized estimating equations. Unicel DxH 800, ADVIA 2120i, and XE 2100 showed 22.8%, 20.2%, and 28.6% slide review rates; 14.3%, 14.3%, and 9.7% false-negative rates; and 13.7, 11.3%, and 17.3% false-positive rates, respectively. All analyzers showed significantly higher false-negative rates than that of the consensus group (2.9%). False-negative rates were higher than the recommended levels. Among 3 automated hematologic analyzers, XE 2100 showed the highest rate of slide review. Because the present study clearly shows that the slide review rates have distinct characteristics among the studied analyzers, each individual laboratory should consider selecting the most appropriate analyzer according to clinical characteristics. Analyzers with high sensitivity may be advantageous in outpatient settings for screening patients, whereas analyzers with high specificity may be beneficial in inpatient settings for efficient patient care.

  13. Comparison of five automated hematology analyzers in a university hospital setting: Abbott Cell-Dyn Sapphire, Beckman Coulter DxH 800, Siemens Advia 2120i, Sysmex XE-5000, and Sysmex XN-2000.

    Bruegel, Mathias; Nagel, Dorothea; Funk, Manuela; Fuhrmann, Petra; Zander, Johannes; Teupser, Daniel

    2015-06-01

    Various types of automated hematology analyzers are used in clinical laboratories. Here, we performed a side-by-side comparison of five current top of the range routine hematology analyzers in the setting of a university hospital central laboratory. Complete blood counts (CBC), differentials, reticulocyte and nucleated red blood cell (NRBC) counts of 349 patient samples, randomly taken out of routine diagnostics, were analyzed with Cell-Dyn Sapphire (Abbott), DxH 800 (Beckman Coulter), Advia 2120i (Siemens), XE-5000 and XN-2000 (Sysmex). Inter-instrument comparison of CBCs including reticulocyte and NRBC counts and investigation of flagging quality in relation to microscopy were performed with the complete set of samples. Inter-instrument comparison of five-part differential was performed using samples without atypical cells in blood smear (n=292). Automated five-part differentials and NRBCs were additionally compared with microscopy. The five analyzers showed a good concordance for basic blood count parameters. Correlations between instruments were less well for reticulocyte counts, NRBCs, and differentials. The poorest concordance for NRBCs with microscopy was observed for Advia 2120i (Kendall's τb=0.37). The highest flagging sensitivity for blasts was observed for XN-2000 (97% compared to 65%-76% for other analyzers), whereas overall specificity was comparable between different instruments. To the best of our knowledge, this is the most comprehensive side-by-side comparison of five current top of the range routine hematology analyzers. Variable analyzer quality and parameter specific limitations must be considered in defining laboratory algorithms in clinical practice.

  14. Hematological dosimetry

    Fluery-Herard, A.

    1991-01-01

    The principles of hematological dosimetry after acute or protracted whole-body irradiation are reviewed. In both cases, over-exposure is never homogeneous and the clinical consequences, viz medullary aplasia, are directly associated with the mean absorbed dose and the seriousness and location of the overexposure. The main hematological data required to assess the seriousness of exposure are the following: repeated blood analysis, blood precursor cultures, as indicators of whole-body exposure; bone marrow puncture, medullary precursor cultures and medullary scintigraphy as indicators of the importance of a local over-exposure and capacity for spontaneous repair. These paraclinical investigations, which are essential for diagnosis and dosimetry, are also used for surveillance and for the main therapeutic issues [fr

  15. IEA PVPS Task 3. Use of photovoltaic systems in stand-alone and island applications. 'Swiss participation'; IEA PVPS Task 3. Use of photovoltaic systems in stand-alone and island applications. 'Participation Suisse'

    Villoz, M. [Dynatex SA, Morges (Switzerland)

    2004-07-01

    This report describes the work done during five years of the second phase of Task 3 of the photovoltaic power systems programme of the International Energy Agency (IEA-PVPS). Task 3 activities were concentrated on stand-alone photovoltaic systems with the main effort on improving the quality and reducing the cost of these systems. The work was divided in 2 sub-tasks whose first one was concentrated on quality insurance schemes and second one on technical recommendations coming from practical experience. Twelve original reports have been published covering topics that can be sorted in 4 categories: the first one is dedicated on quality issues with a review of existing standards in the participating countries and a double paper giving quality assurance recommendations on project management and examples of applying these rules in practical cases. The second category dwelled on photovoltaic systems with papers on charge controllers, on lightning protection and monitoring of systems. The third category presents interesting studies on the storage of energy which remains the main subject where improvements should be made in order to lower the cost of energy; four papers describe the management and the test procedures of lead-acid batteries, how to choose a lead-acid battery and finally are there alternatives to lead-acid batteries for the storage of photovoltaic electricity. The last category worked on loads and users of renewable energy and gives a large amount of experience with loads, how to choose them and how the energy can be better used through demand side management. (author)

  16. Hardware Realization of an Ethernet Packet Analyzer Search Engine

    2000-06-30

    specific for the home automation industry. This analyzer will be at the gateway of a network and analyze Ethernet packets as they go by. It will keep... home automation and not the computer network. This system is a stand-alone real-time network analyzer capable of decoding Ethernet protocols. The

  17. Search Improvement Process-Chaotic Optimization-Particle Swarm Optimization-Elite Retention Strategy and Improved Combined Cooling-Heating-Power Strategy Based Two-Time Scale Multi-Objective Optimization Model for Stand-Alone Microgrid Operation

    Fei Wang

    2017-11-01

    Full Text Available The optimal dispatching model for a stand-alone microgrid (MG is of great importance to its operation reliability and economy. This paper aims at addressing the difficulties in improving the operational economy and maintaining the power balance under uncertain load demand and renewable generation, which could be even worse in such abnormal conditions as storms or abnormally low or high temperatures. A new two-time scale multi-objective optimization model, including day-ahead cursory scheduling and real-time scheduling for finer adjustments, is proposed to optimize the operational cost, load shedding compensation and environmental benefit of stand-alone MG through controllable load (CL and multi-distributed generations (DGs. The main novelty of the proposed model is that the synergetic response of CL and energy storage system (ESS in real-time scheduling offset the operation uncertainty quickly. And the improved dispatch strategy for combined cooling-heating-power (CCHP enhanced the system economy while the comfort is guaranteed. An improved algorithm, Search Improvement Process-Chaotic Optimization-Particle Swarm Optimization-Elite Retention Strategy (SIP-CO-PSO-ERS algorithm with strong searching capability and fast convergence speed, was presented to deal with the problem brought by the increased errors between actual renewable generation and load and prior predictions. Four typical scenarios are designed according to the combinations of day types (work day or weekend and weather categories (sunny or rainy to verify the performance of the presented dispatch strategy. The simulation results show that the proposed two-time scale model and SIP-CO-PSO-ERS algorithm exhibit better performance in adaptability, convergence speed and search ability than conventional methods for the stand-alone MG’s operation.

  18. The international phase 4 validation study of the EORTC QLQ-SWB32: a stand-alone measure of spiritual wellbeing (SWB) for people receiving palliative care for cancer

    Vivat, B.; Young, T.; Winstanley, J.; Arraras, J.; Black, K.; Boyle, F.; Brédart, A.; Costantini, A.; Guo, J.; Irarrazaval, M. E.; Kobayashi, K.; Kruizinga, R.; Navarro, M.; Omidvari, S.; Rohde, G. E.

    2017-01-01

    The EORTC Quality of Life (QL) Group has just completed the final phase (field-testing and validation) of an international project to develop a stand-alone measure of spiritual wellbeing (SWB) for palliative cancer patients. Participants (n= 451) - from 14 countries on four continents; 54% female; 188 Christian, 50 Muslim, 156 with no religion - completed a provisional 36-item measure of SWB plus the EORTC QLQ-C15-PAL (PAL), then took part in a structured debriefing interview. All items showe...

  19. Feasibility Analysis and Simulation of a Stand-Alone Photovoltaic Energy System for Electricity Generation and Environmental Sustainability – Equivalent to 650VA Fuel-Powered Generator – Popularly Known as “I Pass My Neighbour”

    Ani, Vincent Anayochukwu

    2015-01-01

    Photovoltaic (PV) power system can be used to replace wholly 650VA generator for electricity generation for household use in Nigeria. This paper presented the feasibility analysis of load data and simulation study of a stand-alone PV power system that produced the electrical needs of a household. This study is based on designing of PV energy system for household use. The patterns of load consumption within the household were studied and suitably modeled for simulation. The simulation study indicates that energy requirements to provide electricity, which is equivalent to 650VA generator for household use in Nigeria, can be accomplished by 520 W solar PV array, 2312 Ah nominal capacity battery, and a 1 kW DC/AC inverter. This would be suitable for deployment of 100% clean energy for environmental sustainability and uninterruptable power performance in the household. The results of this research show that, with a low-power consuming appliances, it is possible to meet the entire annual electricity demand of a single household solely through a stand-alone PV energy supply. Installing solar panels by most Nigerian home can significantly reduce home reliance on government power thereby reduce the strain on the current capacity of our power generation infrastructure. A detailed design and description of the system were presented in this paper.

  20. Feasibility Analysis and Simulation of a Stand-Alone Photovoltaic Energy System for Electricity Generation and Environmental Sustainability – Equivalent to 650VA Fuel-Powered Generator – Popularly Known as “I Pass My Neighbour”

    Ani, Vincent Anayochukwu, E-mail: vincent_ani@yahoo.com [Department of Electronic Engineering, University of Nigeria Nsukka, Nsukka (Nigeria)

    2015-09-11

    Photovoltaic (PV) power system can be used to replace wholly 650VA generator for electricity generation for household use in Nigeria. This paper presented the feasibility analysis of load data and simulation study of a stand-alone PV power system that produced the electrical needs of a household. This study is based on designing of PV energy system for household use. The patterns of load consumption within the household were studied and suitably modeled for simulation. The simulation study indicates that energy requirements to provide electricity, which is equivalent to 650VA generator for household use in Nigeria, can be accomplished by 520 W solar PV array, 2312 Ah nominal capacity battery, and a 1 kW DC/AC inverter. This would be suitable for deployment of 100% clean energy for environmental sustainability and uninterruptable power performance in the household. The results of this research show that, with a low-power consuming appliances, it is possible to meet the entire annual electricity demand of a single household solely through a stand-alone PV energy supply. Installing solar panels by most Nigerian home can significantly reduce home reliance on government power thereby reduce the strain on the current capacity of our power generation infrastructure. A detailed design and description of the system were presented in this paper.

  1. Use of Six Sigma Worksheets for assessment of internal and external failure costs associated with candidate quality control rules for an ADVIA 120 hematology analyzer.

    Cian, Francesco; Villiers, Elisabeth; Archer, Joy; Pitorri, Francesca; Freeman, Kathleen

    2014-06-01

    Quality control (QC) validation is an essential tool in total quality management of a veterinary clinical pathology laboratory. Cost-analysis can be a valuable technique to help identify an appropriate QC procedure for the laboratory, although this has never been reported in veterinary medicine. The aim of this study was to determine the applicability of the Six Sigma Quality Cost Worksheets in the evaluation of possible candidate QC rules identified by QC validation. Three months of internal QC records were analyzed. EZ Rules 3 software was used to evaluate candidate QC procedures, and the costs associated with the application of different QC rules were calculated using the Six Sigma Quality Cost Worksheets. The costs associated with the current and the candidate QC rules were compared, and the amount of cost savings was calculated. There was a significant saving when the candidate 1-2.5s, n = 3 rule was applied instead of the currently utilized 1-2s, n = 3 rule. The savings were 75% per year (£ 8232.5) based on re-evaluating all of the patient samples in addition to the controls, and 72% per year (£ 822.4) based on re-analyzing only the control materials. The savings were also shown to change accordingly with the number of samples analyzed and with the number of daily QC procedures performed. These calculations demonstrated the importance of the selection of an appropriate QC procedure, and the usefulness of the Six Sigma Costs Worksheet in determining the most cost-effective rule(s) when several candidate rules are identified by QC validation. © 2014 American Society for Veterinary Clinical Pathology and European Society for Veterinary Clinical Pathology.

  2. Evaluation of cell count and classification capabilities in body fluids using a fully automated Sysmex XN equipped with high-sensitive Analysis (hsA) mode and DI-60 hematology analyzer system.

    Takemura, Hiroyuki; Ai, Tomohiko; Kimura, Konobu; Nagasaka, Kaori; Takahashi, Toshihiro; Tsuchiya, Koji; Yang, Haeun; Konishi, Aya; Uchihashi, Kinya; Horii, Takashi; Tabe, Yoko; Ohsaka, Akimichi

    2018-01-01

    The XN series automated hematology analyzer has been equipped with a body fluid (BF) mode to count and differentiate leukocytes in BF samples including cerebrospinal fluid (CSF). However, its diagnostic accuracy is not reliable for CSF samples with low cell concentration at the border between normal and pathologic level. To overcome this limitation, a new flow cytometry-based technology, termed "high sensitive analysis (hsA) mode," has been developed. In addition, the XN series analyzer has been equipped with the automated digital cell imaging analyzer DI-60 to classify cell morphology including normal leukocytes differential and abnormal malignant cells detection. Using various BF samples, we evaluated the performance of the XN-hsA mode and DI-60 compared to manual microscopic examination. The reproducibility of the XN-hsA mode showed good results in samples with low cell densities (coefficient of variation; % CV: 7.8% for 6 cells/μL). The linearity of the XN-hsA mode was established up to 938 cells/μL. The cell number obtained using the XN-hsA mode correlated highly with the corresponding microscopic examination. Good correlation was also observed between the DI-60 analyses and manual microscopic classification for all leukocyte types, except monocytes. In conclusion, the combined use of cell counting with the XN-hsA mode and automated morphological analyses using the DI-60 mode is potentially useful for the automated analysis of BF cells.

  3. Automated quantification of apoptosis in B-cell chronic lymphoproliferative disorders: a prognostic variable obtained with the Cell-Dyn Sapphire (Abbott) automated hematology analyzer.

    Fumi, M; Martins, D; Pancione, Y; Sale, S; Rocco, V

    2014-12-01

    B-chronic lymphocytic leukemia CLL, a neoplastic clonal disorder with monomorphous small B lymphocytes with scanty cytoplasm and clumped chromatin, can be morphologically differentiated in typical and atypical forms with different prognosis: Smudge cells (Gumprecht's shadows) are one of the well-known features of the typical CLL and are much less inconsistent in other different types CLPD. Abbott Cell-Dyn Sapphire uses the fluorescence after staining with the DNA fluorochrome propidium iodide for the measurement of nucleated red blood cells (NRBCs) and nonviable cells (FL3+ cell fraction): We have studied the possible correlation between presence and number of morphologically identifiable smudge cells on smears and the percentage of nonviable cells produced by Cell-Dyn Sapphire. 305 blood samples from 224 patients with B-cell lymphoproliferative disorders and 40 healthy blood donors were analyzed by CBC performed by Cell-Dyn Sapphire, peripheral blood smear, and immunophenotype characterization. FL3+ fraction in CLPD directly correlated with the percentage of smudge cells and is significantly increased in patients with typical B-CLL. This phenomenon is much less evident in patients with atypical/mixed B-CLL and B-NHL. In small laboratories without FCM and cytogenetic, smudge cells%, can be utilized as a preliminary diagnostic and prognostic tool in differential diagnosis of CLPD. © 2014 John Wiley & Sons Ltd.

  4. Is the radiographic subsidence of stand-alone cages associated with adverse clinical outcomes after cervical spine fusion? An observational cohort study with 2-year follow-up outcome scoring.

    Zajonz, Dirk; Franke, Anne-Catherine; von der Höh, Nicolas; Voelker, Anna; Moche, Michael; Gulow, Jens; Heyde, Christoph-Eckhard

    2014-01-01

    The stand-alone treatment of degenerative cervical spine pathologies is a proven method in clinical practice. However, its impact on subsidence, the resulting changes to the profile of the cervical spine and the possible influence of clinical results compared to treatment with additive plate osteosynthesis remain under discussion until present. This study was designed as a retrospective observational cohort study to test the hypothesis that radiographic subsidence of cervical cages is not associated with adverse clinical outcomes. 33 cervical segments were treated surgically by ACDF with stand-alone cage in 17 patients (11 female, 6 male), mean age 56 years (33-82 years), and re-examined after eight and twenty-six months (mean) by means of radiology and score assessment (Medical Outcomes Study Short Form (MOS-SF 36), Oswestry Neck Disability Index (ONDI), painDETECT questionnaire and the visual analogue scale (VAS)). Subsidence was observed in 50.5% of segments (18/33) and 70.6% of patients (12/17). 36.3% of cases of subsidence (12/33) were observed after eight months during mean time of follow-up 1. After 26 months during mean time of follow-up 2, full radiographic fusion was seen in 100%. MOS-SF 36, ONDI and VAS did not show any significant difference between cases with and without subsidence in the two-sample t-test. Only in one type of scoring (painDETECT questionnaire) did a statistically significant difference in t-Test emerge between the two groups (p = 0.03; α = 0.05). However, preoperative painDETECT score differ significantly between patients with subsidence (13.3 falling to 12.6) and patients without subsidence (7.8 dropped to 6.3). The radiological findings indicated 100% healing after stand-alone treatment with ACDF. Subsidence occurred in 50% of the segments treated. No impact on the clinical results was detected in the medium-term study period.

  5. Impact of air-sea drag coefficient for latent heat flux on large scale climate in coupled and atmosphere stand-alone simulations

    Torres, Olivier; Braconnot, Pascale; Marti, Olivier; Gential, Luc

    2018-05-01

    The turbulent fluxes across the ocean/atmosphere interface represent one of the principal driving forces of the global atmospheric and oceanic circulation. Despite decades of effort and improvements, representation of these fluxes still presents a challenge due to the small-scale acting turbulent processes compared to the resolved scales of the models. Beyond this subgrid parameterization issue, a comprehensive understanding of the impact of air-sea interactions on the climate system is still lacking. In this paper we investigates the large-scale impacts of the transfer coefficient used to compute turbulent heat fluxes with the IPSL-CM4 climate model in which the surface bulk formula is modified. Analyzing both atmosphere and coupled ocean-atmosphere general circulation model (AGCM, OAGCM) simulations allows us to study the direct effect and the mechanisms of adjustment to this modification. We focus on the representation of latent heat flux in the tropics. We show that the heat transfer coefficients are highly similar for a given parameterization between AGCM and OAGCM simulations. Although the same areas are impacted in both kind of simulations, the differences in surface heat fluxes are substantial. A regional modification of heat transfer coefficient has more impact than uniform modification in AGCM simulations while in OAGCM simulations, the opposite is observed. By studying the global energetics and the atmospheric circulation response to the modification, we highlight the role of the ocean in dampening a large part of the disturbance. Modification of the heat exchange coefficient modifies the way the coupled system works due to the link between atmospheric circulation and SST, and the different feedbacks between ocean and atmosphere. The adjustment that takes place implies a balance of net incoming solar radiation that is the same in all simulations. As there is no change in model physics other than drag coefficient, we obtain similar latent heat flux

  6. Techno-Economic Evaluation of a Stand-Alone Power System Based on Solar Power/Batteries for Global System for Mobile Communications Base Stations

    Mohammed H. Alsharif

    2017-03-01

    Full Text Available Energy consumption in cellular networks is receiving significant attention from academia and the industry due to its significant potential economic and ecological influence. Energy efficiency and renewable energy are the main pillars of sustainability and environmental compatibility. Technological advancements and cost reduction for photovoltaics are making cellular base stations (BSs; a key source of energy consumption in cellular networks powered by solar energy sources a long-term promising solution for the mobile cellular network industry. This paper addresses issues of deployment and operation of two solar-powered global system for mobile communications (GSM BSs that are being deployed at present (GSM BS 2/2/2 and GSM BS 4/4/4. The study is based on the characteristics of South Korean solar radiation exposure. The optimum criteria as well as economic and technical feasibility for various BSs are analyzed using a hybrid optimization model for electric renewables. In addition, initial capital, replacement, operations, maintenance, and total net present costs for various solar-powered BSs are discussed. Furthermore, the economic feasibility of the proposed solar system is compared with conventional energy sources in urban and remote areas.

  7. Stand alone biofuel production from algae

    Wijffels, R.H.; Janssen, M.G.J.; Barbosa, M.J.

    2011-01-01

    In this feature, leading researchers in the field of microbial biotechnology speculate on the technical and conceptual developments that will drive innovative research and open new vistas over the next few years

  8. Informing Approaches in Establishing Stand Alone Community ...

    Literacy is usually considered the ability to read at a basic level. Now it is beginning to be defined more broadly to include applying reading, writing, and mathematical skills to obtain and use information and solve problems at levels of proficiency necessary to function in society, to achieve one's goals and develop one's ...

  9. Stand Alone Battery Thermal Management System

    Brodie, Brad [Denso International America, Incorporated, Southfield, MI (United States)

    2015-09-30

    The objective of this project is research, development and demonstration of innovative thermal management concepts that reduce the cell or battery weight, complexity (component count) and/or cost by at least 20%. The project addresses two issues that are common problems with current state of the art lithium ion battery packs used in vehicles; low power at cold temperatures and reduced battery life when exposed to high temperatures. Typically, battery packs are “oversized” to satisfy the two issues mentioned above. The first phase of the project was spent making a battery pack simulation model using AMEsim software. The battery pack used as a benchmark was from the Fiat 500EV. FCA and NREL provided vehicle data and cell data that allowed an accurate model to be created that matched the electrical and thermal characteristics of the actual battery pack. The second phase involved using the battery model from the first phase and evaluate different thermal management concepts. In the end, a gas injection heat pump system was chosen as the dedicated thermal system to both heat and cool the battery pack. Based on the simulation model. The heat pump system could use 50% less energy to heat the battery pack in -20°C ambient conditions, and by keeping the battery cooler at hot climates, the battery pack size could be reduced by 5% and still meet the warranty requirements. During the final phase, the actual battery pack and heat pump system were installed in a test bench at DENSO to validate the simulation results. Also during this phase, the system was moved to NREL where testing was also done to validate the results. In conclusion, the heat pump system can improve “fuel economy” (for electric vehicle) by 12% average in cold climates. Also, the battery pack size, or capacity, could be reduced 5%, or if pack size is kept constant, the pack life could be increased by two years. Finally, the total battery pack and thermal system cost could be reduced 5% only if the system is integrated with the vehicle cabin air conditioning system. The reason why we were not able to achieve the 20% reduction target is because of the natural decay of the battery cell due to the number of cycles. Perhaps newer battery chemistries that are not so sensitive to cycling would have more potential for reducing the battery size due to thermal issues.

  10. Chapter 2: Stand-alone Applications - TOPCAT

    Miller, C. J.

    Tool for OPerations on Catalogues And Tables or TOPCAT is a graphical viewer for table data. It offers a variety of ways to work with data tables, including a browser for the cell data, viewers for information about table and column metadata, dataset visualization, and even analysis. We discuss a small subset of TOPCAT's functionalities in this chapter. TOPCAT was originally developed as part of the Starlink program in the United Kingdom. It is now maintained by AstroGrid. The program is written in pure Java and available under the GNU General Public License. It is available for download and a version is included in the software distribution accompanying this book. TOPCAT is a GUI interface on top of the STIL library. A command line interface to this library, STILTS, described in Chapter 21 provides scriptable access to many of the capabilities described here. The purpose of this tutorial is to provide an overview of TOPCAT to the novice user. The best place to look for and learn about TOPCAT is the web page maintained by Mark B. Taylor. There, TOPCAT documentation is provided in HTML, PDF, via screen shots, etc. In this chapter we take the user through a few examples that give the general idea of how TOPCAT works. The majority of the functionality of TOPCAT is not included in this short tutorial. Our goal in this tutorial is to lead the reader through an exercise that would result in a publication quality figure (e.g. for a journal article). Specifically, we will use TOPCAT to show how the color-magnitude relation of a galaxy cluster compares to that of all galaxies in the Sloan Digital Sky Survey (York et al. 2000). This diagnostic is used not only in cluster finding, but its linear fit can provide insight into the age and/or metallicity of the oldest galaxies in galaxy clusters (which are some of the oldest galaxies in the Universe). The data we need for this exercise are: 1) the entire spectroscopic galaxy catalog from the SDSS, with galaxy positions, galaxy redshifts, and galaxy magnitudes and 2) galaxy members of a known galaxy cluster. For the former, we will download data directly from the SDSS servers to our local machine for analysis. For the latter, we will use TOPCAT's ability to call live cone search services.

  11. Multi-site evaluation of a computer aided detection (CAD) algorithm for small acute intra-cranial hemorrhage and development of a stand-alone CAD system ready for deployment in a clinical environment

    Deshpande, Ruchi R.; Fernandez, James; Lee, Joon K.; Chan, Tao; Liu, Brent J.; Huang, H. K.

    2010-03-01

    Timely detection of Acute Intra-cranial Hemorrhage (AIH) in an emergency environment is essential for the triage of patients suffering from Traumatic Brain Injury. Moreover, the small size of lesions and lack of experience on the reader's part could lead to difficulties in the detection of AIH. A CT based CAD algorithm for the detection of AIH has been developed in order to improve upon the current standard of identification and treatment of AIH. A retrospective analysis of the algorithm has already been carried out with 135 AIH CT studies with 135 matched normal head CT studies from the Los Angeles County General Hospital/ University of Southern California Hospital System (LAC/USC). In the next step, AIH studies have been collected from Walter Reed Army Medical Center, and are currently being processed using the AIH CAD system as part of implementing a multi-site assessment and evaluation of the performance of the algorithm. The sensitivity and specificity numbers from the Walter Reed study will be compared with the numbers from the LAC/USC study to determine if there are differences in the presentation and detection due to the difference in the nature of trauma between the two sites. Simultaneously, a stand-alone system with a user friendly GUI has been developed to facilitate implementation in a clinical setting.

  12. The international phase 4 validation study of the EORTC QLQ-SWB32: A stand-alone measure of spiritual well-being for people receiving palliative care for cancer.

    Vivat, B; Young, T E; Winstanley, J; Arraras, J I; Black, K; Boyle, F; Bredart, A; Costantini, A; Guo, J; Irarrazaval, M E; Kobayashi, K; Kruizinga, R; Navarro, M; Omidvari, S; Rohde, G E; Serpentini, S; Spry, N; Van Laarhoven, H W M; Yang, G M

    2017-11-01

    The EORTC Quality of Life Group has just completed the final phase (field-testing and validation) of an international project to develop a stand-alone measure of spiritual well-being (SWB) for palliative cancer patients. Participants (n = 451)-from 14 countries on four continents; 54% female; 188 Christian; 50 Muslim; 156 with no religion-completed a provisional 36-item measure of SWB plus the EORTC QLQ-C15-PAL (PAL), then took part in a structured debriefing interview. All items showed good score distribution across response categories. We assessed scale structure using principal component analysis and Rasch analysis, and explored construct validity, and convergent/divergent validity with the PAL. Twenty-two items in four scoring scales (Relationship with Self, Relationships with Others, Relationship with Someone or Something Greater, and Existential) explained 53% of the variance. The measure also includes a global SWB item and nine other items. Scores on the PAL global quality-of-life item and Emotional Functioning scale weakly-moderately correlated with scores on the global SWB item and two of the four SWB scales. This new validated 32-item SWB measure addresses a distinct aspect of quality-of-life, and is now available for use in research and clinical practice, with a role as both a measurement and an intervention tool. © 2017 John Wiley & Sons Ltd.

  13. Hematological evaluation of splenomegaly

    Ali, N.; Anwar, M.; Ayyub, M.; Ejaz, A.; Nadeem, M.; Qureshi, A.H.; Qamar, M.A.

    2004-01-01

    Objective: To find out the relative frequency of clinical conditions associated with splenomegaly that require hematological evaluation in our set up. Subjects and Methods: Patients of either gender or all age groups with palpable spleen was included. Patients with splenomegaly due to liver disease, malarial parasites on thick or thin blood film, positive Widal test, or positive blood cultures were excluded from study. Patients were initially evaluated with clinical history, microscopic examination of blood smear, and blood counts. Depending upon provisional diagnosis bone marrow examination or investigations for hemolytic anemia were performed. Results: One hundred patients were received. Seventy-eight patients were adults and 22 patients were of pediatric age group. In the adults, hematological malignancies were seen in 37%, malarial parasites in bone marrow in 20.5%, megaloblastic anemia in 13%, bacterial infections in 9%, hemolytic anemia in 9%, tropical splenomegaly in 5%, and positive bone marrow culture for salmonella in 6.5%. In children, hematological evaluation revealed hematological malignancies in 18%, beta thalassaemia in 55%, other hemolytic anemias in 13.5%, congenital sideroblastic anemia in 4.5%, and storage disorder in 9%. Conclusion: Hematological workup is informative in most of the cases. Bone marrow examination is the key investigation, hematological malignancies constituted 37% of the adult and 18% of pediatric age group patients. Hemolytic anemia constituted 68% of pediatric age group. (author)

  14. Tiny Integrated Network Analyzer for Noninvasive Measurements of Electrically Small Antennas

    Buskgaard, Emil Feldborg; Krøyer, Ben; Tatomirescu, Alexandru

    2016-01-01

    the system. The tiny integrated network analyzer is a stand-alone Arduino-based measurement system that utilizes the transmit signal of the system under test as its reference. It features a power meter with triggering ability, on-board memory, universal serial bus, and easy extendibility with general...

  15. Post-processing in cardiovascular computed tomography. Performance of a client server solution versus a stand-alone solution; Bildnachverarbeitung in der kardiovaskulaeren Computertomografie. Performance von Client-Server- versus Einzelplatzloesung

    Luecke, C.; Foldyna, B.; Andres, C.; Grothoff, M.; Nitzsche, S.; Gutberlet, M.; Lehmkuhl, L. [Leipzig Univ. - Herzzentrum (Germany). Abt. fuer Diagnostische und Interventionelle Radiologie; Boehmer-Lasthaus, S. [Siemens Healthcare Sector, Erlangen (Germany). Imaging and Therapy Div.

    2014-12-15

    Purpose: To compare the performance of server-based (CSS) versus stand-alone post-processing software (ES) for the evaluation of cardiovascular CT examinations (cvCT) and to determine the crucial steps. Data of 40 patients (20 patients for coronary artery evaluation and 20 patients prior to transcatheter aortic valve implantation [TAVI]) were evaluated by 5 radiologists with CSS and ES. Data acquisition was performed using a dual-source 128-row CT unit (SOMATOM Definition Flash, Siemens, Erlangen, Germany) and a 64-row CT unit (Brilliance 64, Philips, Hamburg, Germany). The following workflow was evaluated: Data loading, aorta and coronary segmentation, curved multiplanar reconstruction (cMPR) and 3 D volume rendering technique (3D-VRT), measuring of coronary artery stenosis and planimetry of the aortic annulus. The time requirement and subjective quality for the workflow were evaluated. The coronary arteries as well as the TAVI data could be evaluated significantly faster with CSS (5.5 ± 2.9 min and 8.2 ± 4.0 min, respectively) than with ES (13.9 ± 5.2 min and 15.2 ± 10.9 min, respectively, p = 0.01). Segmentation of the aorta (CSS: 1.9 ± 2.0 min, ES: 3.7 ± 3.3 min), generating cMPR of coronaries (CSS: 0.5 ± 0.2 min, ES: 5.1 ± 2.6 min), aorta and iliac vessels (CSS: 0.5 ± 0.4 min and 0.4 ± 0.4 min, respectively, ES: 1.6 ± 0.7 min and 2.8 ± 3 min, respectively) could be performed significantly faster with CSS than with ES with higher quality of cMPR, measuring of coronary stenosis and 3D-VRT (p < 0.05). Evaluation of cvCT can be accomplished significantly faster and better with CSS than with ES. The segmentation remains the most time-consuming workflow step, so optimization of segmentation algorithms could improve performance even further.

  16. [Application of a stand-alone interbody fusion cage based on a novel porous TiO2/glass composite. I. Implantation in the sheep cervical spine and radiological evaluation].

    Korinth, M C; Hero, T; Mahnken, A H; Ragoss, C; Scherer, K

    2004-12-01

    Animals are becoming more and more common as in vitro and in vivo models for the human spine. Especially the sheep cervical spine is stated to be of good comparability and usefulness in the evaluation of in vivo radiological, biomechanical and histological behaviour of new bone replacement materials, implants and cages for cervical spine interbody fusion. In preceding biomechanical in vitro examination human cervical spine specimens were tested after fusion with either a cubical stand-alone interbody fusion cage manufactured from a new porous TiO/glass composite (Ecopore) or polymethyl-methacrylate (PMMA) after discectomy. First experience with the use of the new material and its influence on the primary stability after in vitro application were gained. After fusion of 10 sheep cervical spines in the levels C2/3 and C4/5 in each case with PMMA and with an Ecopore-cage, radiologic as well as computertomographic examinations were performed postoperatively and every 4 weeks during the following 2 and 4 months, respectively. Apart from establishing our animal model, we analysed the radiological changes and the degree of bony fusion of the operated segments during the course. In addition we performed measurements of the corresponding disc space heights (DSH) and intervertebral angles (IVA) for comparison among each other, during the course and with the initial values. Immediately after placement of both implants in the disc spaces the mean DSH and IVA increased (34.8% and 53.9%, respectively). During the following months DSH decreased to a greater extent in the Ecopore-segments than in the PMMA-segments, even to a value below the initial value (p>0.05). Similarly, the IVA decreased in both groups in the postoperative time lapse, but more distinct in the Ecopore-segments (pmodel of the sheep cervical spine. Distinct radiological changes regarding evident subsidence and detectable fusion of the segments, operated on with the new biomaterial, were seen. We demonstrated the

  17. STAND-ALONE WIND ENERGY CONVERSION SYSTEM WITH MAXIMUM POWER TRANSFER CONTROL SISTEMA AISLADO DE CONVERSIÓN EÓLICA CON CONTROL DE MÁXIMA TRANSFERENCIA DE POTENCIA

    Miguel López

    2009-12-01

    Full Text Available A controlled wind generation system for a stand alone application is presented in this paper. A cascaded step-up/step-down power electronic converters topology is proposed to control the wind power system in the whole wind speed range. For the low wind speed range, the control strategy is aimed to follow the wind turbine’s maximal power coefficient by adjusting the generator’s rotational speed. For high wind speeds, the system power regulation is also made by controlling the generator speed. This control is made by the DC/DC power electronic converter, which modifies its input voltage, changing the machine voltage and consequently varying the generator’s rotor speed. The proposed system is validated by computer simulation. The proposed control system shows a good performance for its application in autonomous wind energy systems.Un sistema de generación eólica para una aplicación aislada es presentado en este artículo. Una topología de convertidores electrónicos de potencia elevador y reductor conectados en cascada es propuesta para controlar la producción eólica en todo el rango de velocidades del viento. Para el rango de vientos suaves, la estrategia de control permite seguir el máximo coeficiente de potencia de turbina eólica mediante el ajuste de la velocidad de rotación del generador. En el rango de vientos fuertes, la regulación de la potencia del sistema se hace igualmente por control de la velocidad de giro del generador. La acción de control es realizada mediante el convertidor DC/DC de potencia el cual modifica su tensión de entrada, cambiando así la tensión en los terminales de la máquina y por consecuencia variando la velocidad de rotación del generador. El sistema propuesto es validado mediante simulación por computador. Los resultados muestran que el sistema de control propuesto actúa de buena manera para su aplicación en sistemas autónomos de generación eólica.

  18. Hematology of camelids.

    Vap, Linda; Bohn, Andrea A

    2015-01-01

    Interpretation of camelid hematology results is similar to that of other mammals. Obtaining accurate results and using appropriate reference intervals can be a bit problematic, particularly when evaluating the erythron. Camelid erythrocytes vary from other mammals in that they are small, flat, and elliptical. This variation makes data obtained from samples collected from these species prone to error when using some automated instruments. Normal and abnormal findings in camelid blood are reviewed as well as how to ensure accurate results.

  19. The European Hematology Association Roadmap for European Hematology Research

    Engert, Andreas; Balduini, Carlo; Brand, Anneke

    2016-01-01

    The European Hematology Association (EHA) Roadmap for European Hematology Research highlights major achievements in diagnosis and treatment of blood disorders and identifies the greatest unmet clinical and scientific needs in those areas to enable better funded, more focused European hematology...... research. Initiated by the EHA, around 300 experts contributed to the consensus document, which will help European policy makers, research funders, research organizations, researchers, and patient groups make better informed decisions on hematology research. It also aims to raise public awareness...... of the burden of blood disorders on European society, which purely in economic terms is estimated at €23 billion per year, a level of cost that is not matched in current European hematology research funding. In recent decades, hematology research has improved our fundamental understanding of the biology...

  20. The role of cytokines in development of hematological and immune disorders at radiation therapy for uterine body cancer

    Sorochan, P.P.; Prokhach, N.E.; Gromakova, Yi.A.; Krugova, Yi.M.; Sukhyin, V.S.

    2013-01-01

    The changes in hematological and immune parameters in patients with uterine body cancer were analyzed by the stages of the combined treatment. The rol of cytokines in the development of hematologic and immune disorders was assessed

  1. Feasibility study of white blood cell count in cerebrospinal fluid and hydrothorax and ascites with Sysmex ;XN-1000 hematology analyzer%SYSMEX XN-1000血球仪在脑脊液和胸腹水白细胞计数中的可行性探讨

    叶小英; 范春丽; 陆敏; 卞洁

    2016-01-01

    Objective To analyze the feasibility of using body fluid module of Sysmex XN-1000 hematology analyzer for white blood cell count in the cerebrospinal fluid (CSF), hydrothorax and ascites. Methods Microscope method and Sysmex XN-1000 hematology analyzer were used to analyze 183 samples of CSF, hydrothorax and ascites at the same time. The measured results were divided into three groups:group A:0~1 000×106/L, B:1 001~5 000×106/L, C:>5 000×106/L. The results were statistically analyzed. Results Compared with the results of microscope, the results of Sysmex XN-1000 hematology analyzer showed no statistically significant difference (P>0.05). The correlation coeffi-cients of group A, B, C were 0.993, 0.984, 0.996, with the regression equation of y=1.007x-1.072, y=1.003+19.776x, y=1.241-1 419.365x, respectively. Conclusion The body fluid module of Sysmex XN-1000 hematology analyzer can be used for white blood cell count in clinical CSF and hydrothorax and ascites, with simple operation and reliable results. When the instrument is alarmed on the sample test, we should use manual microscopy review to improve the veracity and reliability of the results.%目的:探讨SYSMEX XN-1000血液分析仪(简称SYSMEX XN-1000)的体液模式在脑脊液和胸腹水白细胞计数中应用的可行性。方法分别采用手工显微镜镜检法和SYSMEX XN-1000对183例脑脊液和胸腹水标本进行白细胞计数,将所测结果按A:(0~1000)×106/L,B:(1001~5000)×106/L,C:>5000×106/L分为三组,分别进行统计学分析。结果与手工显微镜镜检法相比,SYSMEX XN-1000所测结果差异无统计学意义(P>0.05)。A、B、C三组的相关系数分别为0.993、0.984、0.996,A组回归方程为y=1.007x-1.072,B组回归方程为y=1.003x+19.776,C组回归方程为y=1.241x-1419.365。结论 SYSMEX XN-1000血液分析仪可用于临床脑脊液和胸腹水中白细胞计数,其操作简单易行,结果稳定可靠,但如果仪器进行样品

  2. Hematology reference intervals for neonatal Holstein calves.

    Panousis, Nikolaos; Siachos, Nektarios; Kitkas, Georgios; Kalaitzakis, Emmanouil; Kritsepi-Konstantinou, Maria; Valergakis, Georgios E

    2018-01-09

    Data regarding hematologic reference intervals (RI) for neonatal calves have not been published yet. The aims of this study were: a) to establish hematology RIs for neonatal Holstein calves, b) to compare them with the RIs for lactating cows, and c) to investigate the relationship of age and gender with the hematologic profile of calves. Two-hundred and fifty-four clinically healthy Holstein calves (1-9days old, from 30 farms) and 82 healthy Holstein cows (between 30 and 150days in milk, from 10 farms) were blood sampled once for a complete blood count evaluation, using the ADVIA 120 hematology analyzer. An additional blood sample was collected from each calf for serum total protein concentration measurement. RIs and age-related RIs were calculated with the Reference Value Advisor freeware. Comparisons between calves and cows and between male and female calves were performed with t-test or Mann-Whitney test. Red blood cell count (RBC), white blood cell count (WBC), neutrophil, lymphocyte and platelet counts in calves were higher, while mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC) were lower than in cows. Lymphocyte and platelets showed a notable increase through age. Finally, female calves had higher RBC, hematocrit and hemoglobin concentration than males. Age-specific RIs should be used for the interpretation of the complete blood count in Holstein calves. Copyright © 2018 Elsevier Ltd. All rights reserved.

  3. A comparison of anterior cervical discectomy and fusion (ACDF) using self-locking stand-alone polyetheretherketone (PEEK) cage with ACDF using cage and plate in the treatment of three-level cervical degenerative spondylopathy: a retrospective study with 2-year follow-up.

    Chen, Yuqiao; Lü, Guohua; Wang, Bing; Li, Lei; Kuang, Lei

    2016-07-01

    To evaluate the clinical efficacy and radiological outcomes of anterior cervical discectomy and fusion (ACDF) using self-locking polyetheretherketone (PEEK) cages for treatment of three-level cervical degenerative spondylopathy. Twenty-eight patients underwent three-level ACDF using self-locking stand-alone PEEK cages (group A), and 26 patients underwent three-level ACDF using cages and plate fixation (group B) were reviewed retrospectively. Clinical efficacy was evaluated by pre- and post-operative Japanese Orthopedic Association (JOA) scores and Neck Disability Index (NDI). The operation time, blood loss, surgical results according to Odom's criteria and post-operative dysphagia status were also recorded. Radiological outcomes including fusion, cervical Cobb's lordosis, fused segment angle, disc height, and cage subsidence were assessed. Clinical outcome measures such as dysphagia and fusion rate and the results of surgery evaluated according to Odom's criteria were not statistically significant (P > 0.05) between groups. The operation time was shorter and blood loss was less in group A (P  0.05). Post-operative cage subsidence, the loss of disc height, cervical lordosis and the fused segment angle were relatively higher in group A than group B (P < 0.05). ACDF using self-locking stand-alone cages showed similar clinical results as compared to ACDF using cages and plate fixation for the treatment of three-level cervical degenerative spondylopathy. However, potential long-term problems such as cage subsidence, loss of cervical lordosis and fused segment angle post-operatively were shown to be associated with patients who underwent ACDF using self-locking stand-alone cages.

  4. Centrifugal analyzer development

    Burtis, C.A.; Bauer, M.L.; Bostick, W.D.

    1976-01-01

    The development of the centrifuge fast analyzer (CFA) is reviewed. The development of a miniature CFA with computer data analysis is reported and applications for automated diagnostic chemical and hematological assays are discussed. A portable CFA system with microprocessor was adapted for field assays of air and water samples for environmental pollutants, including ammonia, nitrates, nitrites, phosphates, sulfates, and silica. 83 references

  5. Hematological parameters in children with Down syndrome

    Renato Nisihara

    2015-04-01

    Full Text Available Introduction: There are few studies that investigated whether Down syndrome (DS interferes with references values for complete blood counts (CBC test in children with the syndrome. Objective: This study aimed to analyze the results of CBC performed in children with DS. Patients and methods: Data from CBC of DS children were included; at the time of examination they were aged between 2 and 10 years and had no clinical signs and/or symptoms of infectious disease. The hematological parameters analyzed were: total number of erythrocytes (RBC, hemoglobin (Hb concentration, hematological indices, platelet count, and total number of leucocytes. Additionally, we compared the collected parameters according to gender and age of the children studied. Results: A total of 203 CBC (100 girls and 103 boys were evaluated. In general, no significant differences were observed in studied parameters between the values found in samples of DS children and the values described in the literature as a reference for children in this age group. No difference in the prevalence of anemia was observed in relation to gender (p = 0.33, 14/103 (13.6% boys, and 11/100 (11% girls had anemia. However, the Hb and hematological indices values found in boys was significantly lower than in girls (p < 0.001. Conclusion: This investigation is the first one in Brazil to present and analyze the CBC results of DS children, reporting that their hematological indices are within the expected range for children without DS. Additionally, it was found that 12.3% of them had anemia.

  6. Fiscal 2000 regional new energy vision formulation - Financially aided project. Report on regional new energy vision formulation for Ueno village (Object of survey: Commercialization feasibility study for a stand-alone type wind power generation system at Ueno German Culture Village); 2000 nendo Uenoson chiiki shin energy vision sakutei hokokusho. Ueno Doitsu bunkamura dokuritsugata furyoku hatsuden system jigyoka feasibility study chosa

    NONE

    2001-02-01

    A survey is conducted about the profitability of installing a stand-alone type wind power system at Ueno village (Miyako Island), Okinawa Prefecture. The German Culture Village, which is an integrated resort house provided with accommodations (500 people), educational and cultural facilities, and sports facilities consumes 272 MWh/year in electric power. The results of the survey are summarized in six chapters, which are (1) the survey of the business under the project to be the object of feasibility study, (2) project to be the object of feasibility study, (3) outline of the Okinawa Electric Power Co., Inc., Miyakojima system and problems to ensue from its interconnection with wind turbines, (4) survey of stand-alone type wind turbine power generation systems, (5) technical/economic feasibility study, and (6) project management and future tasks. It is concluded that there will be profit in the presence of a subsidy that covers 65% or more of the total cost of constructing a system comprising three 600 KW wind turbines, three 400 kW class diesel generators, and storage batteries. (NEDO)

  7. Artificial intelligence in hematology.

    Zini, Gina

    2005-10-01

    Artificial intelligence (AI) is a computer based science which aims to simulate human brain faculties using a computational system. A brief history of this new science goes from the creation of the first artificial neuron in 1943 to the first artificial neural network application to genetic algorithms. The potential for a similar technology in medicine has immediately been identified by scientists and researchers. The possibility to store and process all medical knowledge has made this technology very attractive to assist or even surpass clinicians in reaching a diagnosis. Applications of AI in medicine include devices applied to clinical diagnosis in neurology and cardiopulmonary diseases, as well as the use of expert or knowledge-based systems in routine clinical use for diagnosis, therapeutic management and for prognostic evaluation. Biological applications include genome sequencing or DNA gene expression microarrays, modeling gene networks, analysis and clustering of gene expression data, pattern recognition in DNA and proteins, protein structure prediction. In the field of hematology the first devices based on AI have been applied to the routine laboratory data management. New tools concern the differential diagnosis in specific diseases such as anemias, thalassemias and leukemias, based on neural networks trained with data from peripheral blood analysis. A revolution in cancer diagnosis, including the diagnosis of hematological malignancies, has been the introduction of the first microarray based and bioinformatic approach for molecular diagnosis: a systematic approach based on the monitoring of simultaneous expression of thousands of genes using DNA microarray, independently of previous biological knowledge, analysed using AI devices. Using gene profiling, the traditional diagnostic pathways move from clinical to molecular based diagnostic systems.

  8. 42 CFR 493.941 - Hematology (including routine hematology and coagulation).

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Hematology (including routine hematology and....941 Hematology (including routine hematology and coagulation). (a) Program content and frequency of challenge. To be approved for proficiency testing for hematology, a program must provide a minimum of five...

  9. Hematological findings in children with brucellosis.

    Aypak, Adalet; Aypak, Cenk; Bayram, Yasemin

    2015-12-01

    Brucellosis produces a variety of non-specific hematological abnormalities. The aim of the present study was to evaluate the hematological findings in childhood brucellosis. Medical records of children with brucellosis admitted to a tertiary hospital in a 1 year period, were analyzed retrospectively. Sixty-nine patients (mean age, 14.5 ± 3.3 years) were diagnosed with brucellosis. The most common hematological finding was thrombocytopenia (n = 11, 15.9%). Thrombocytosis was detected in five patients (7.3%), leukopenia in four (5.8%), anemia in three (4.3%), and bicytopenia in three (4.3%). None of the patients had pancytopenia. Blood culture was positive for Brucella spp. in 41 patients (59.4%). Among those patients with positive blood culture, six (14.6%) had serum agglutination test titer ≤1/80. Platelet (PLT) count was significantly lower in the bacteremia-positive group. The OR (95%CI) of bacteremia for PLT cut-off 200,000/mm(3) was 0.148 (95%CI: 0.031-0.718) and relative risk was 1.718 (95%CI: 1.244-2.372; P = 0.010). Brucellosis should be kept in mind in the differential diagnosis of isolated thrombocytopenia in pediatric patients from endemic areas. © 2015 Japan Pediatric Society.

  10. Alternative route of process modification for biofuel production by embedding the Fischer-Tropsch plant in existing stand-alone power plant (10 MW) based on biomass gasification - Part I: A conceptual modeling and simulation approach (a case study in Thailand)

    Hunpinyo, Piyapong; Cheali, Peam; Narataruksa, Phavanee

    2014-01-01

    a base case process model coupled with techno-economic evaluation for the FT synthesis. In particular, the FT process configurations are designed and assessed using current kinetic laboratory data by our research group for modeling specific reactions in PFR reactor. The calculation of equipment sizing......The utilization of syngas shows a highly potential to improve the economic potential of the stand-alone power unit-based gasification plants as well as enhancing the growing demand of transportation fuels. The thermochemical conversion of biomass via gasification to heat and power generations from...... incurred several major unit operations is performed for once-through mode (no recycles of unconverted syngas) with electricity co-production. This study provides a detailed base-case model for the synthesis with the capacities of 1, 2 and 3 MW of syngas technology sharing and the comparison between...

  11. Study of a stand alone power system based on a photovoltaic field, an electrolyser and a fuel cell: test bench and modelling; Etude d'un systeme autonome de production d'energie couplant un champ photovoltaique, un electrolyseur et une pile a combustible: realisation d'un banc d'essai et modelisation

    Busquet, S.

    2003-12-01

    Our energetic future has to be based on non-polluting energies with long-term resources. Renewable energies are the best candidates but as their production is intermittent, storage way is necessary as well efficient as environmentally friendly. Coupled an electrolyser and a fuel cell allows to store electricity in gas form and furthermore to produce heat energy. The goal of this work is to evaluate performances of a stand-alone power system, producing electricity and heat, coupling a photovoltaic field and a hydrogen storage system, made of an electrolyser, a gas storage unit and a fuel cell. Hydrogen is the unique way to store electricity. To complete this task, two tools have been developed: a 3,6 kW test bench and a simulation tool. To select the test bench, a bibliographic study enables to collect the necessary information to size and to choice the system and its components. The low availability of components adapted to our application, forces us to create new devices (electrolyser, fuel cell, power management unit). The test bench is automatic and safe. Experimental analysis evaluates the efficiency of the hydrogen storage system, determining the different losses occurring in each component. Modifications are proposed to increase the performances of the storage system. The simulation tool enables to plan the operating of the test bench for a fixed load and place. This model can simulate any system based on experimental data of each component. Simulation results enable to characterise the functioning of the test bench in a stand-alone operation, to determine its performances and to evaluate the influence of the different losses. (author)

  12. The European Hematology Association Roadmap for European Hematology Research : A consensus document

    Engert, Andreas; Balduini, Carlo; Brand, Anneke; Coiffier, Bertrand; Cordonnier, Catherine; Döhner, Hartmut; de Wit, Thom Duyvené; Eichinger, Sabine; Fibbe, Willem; Green, Tony; de Haas, Fleur; Iolascon, Achille; Jaffredo, Thierry; Rodeghiero, Francesco; Salles, Gilles; Schuringa, Jan Jacob

    The European Hematology Association (EHA) Roadmap for European Hematology Research highlights major achievements in diagnosis and treatment of blood disorders and identifies the greatest unmet clinical and scientific needs in those areas to enable better funded, more focused European hematology

  13. Eosinophilic Dermatosis of Hematologic Malignancy.

    Lucas-Truyols, S; Rodrigo-Nicolás, B; Lloret-Ruiz, C; Quecedo-Estébanez, E

    Dermatosis characterized by tissue eosinophilia arising in the context of hematologic disease is known as eosinophilic dermatosis of hematologic malignancy. The most commonly associated malignancy is chronic lymphocytic leukemia. Eosinophilic dermatosis of hematologic malignancy is a rare condition with a wide variety of clinical presentations, ranging from papules, erythematous nodules, or blisters that simulate arthropod bites, to the formation of true plaques of differing sizes. Histology reveals the presence of abundant eosinophils. We present 4 new cases seen in Hospital Arnau de Vilanova, Valencia, during the past 7 years. Three of these cases were associated with chronic lymphocytic leukemia and 1 with mycosis fungoides. It is important to recognize this dermatosis as it can indicate progression of the underlying disease, as was the case in 3 of our patients. Copyright © 2017 AEDV. Publicado por Elsevier España, S.L.U. All rights reserved.

  14. Extracellular Vesicles in Hematological Disorders

    Anat Aharon

    2014-10-01

    Full Text Available Extracellular vesicles (EVs, comprised of exosomes, microparticles, apoptotic bodies, and other microvesicles, are shed from a variety of cells upon cell activation or apoptosis. EVs promote clot formation, mediate pro-inflammatory processes, transfer proteins and miRNA to cells, and induce cell signaling that regulates cell differentiation, proliferation, migration, invasion, and apoptosis. This paper will review the contribution of EVs in hematological disorders, including hemoglobinopathies (sickle cell disease, thalassemia, paroxysmal nocturnal hemoglobinuria, and hematological malignancies (lymphomas, myelomas, and acute and chronic leukemias.

  15. American Society of Pediatric Hematology/Oncology

    ... Learn More Explore career opportunities in pediatric hematology/oncology Visit the ASPHO Career Center. Learn More Join ... Privacy Policy » © The American Society of Pediatric Hematology/Oncology

  16. Performance evaluation of stand alone hybrid PV-wind generator

    Nasir, M. N. M.; Saharuddin, N. Z.; Sulaima, M. F.; Jali, Mohd Hafiz; Bukhari, W. M.; Bohari, Z. H.; Yahaya, M. S.

    2015-01-01

    This paper presents the performance evaluation of standalone hybrid system on Photovoltaic (PV)-Wind generator at Faculty of Electrical Engineering (FKE), UTeM. The hybrid PV-Wind in UTeM system is combining wind turbine system with the solar system and the energy capacity of this hybrid system can generate up to charge the battery and supply the LED street lighting load. The purpose of this project is to evaluate the performance of PV-Wind hybrid generator. Solar radiation meter has been used to measure the solar radiation and anemometer has been used to measure the wind speed. The effectiveness of the PV-Wind system is based on the various data that has been collected and compared between them. The result shows that hybrid system has greater reliability. Based on the solar result, the correlation coefficient shows strong relationship between the two variables of radiation and current. The reading output current followed by fluctuate of solar radiation. However, the correlation coefficient is shows moderate relationship between the two variables of wind speed and voltage. Hence, the wind turbine system in FKE show does not operate consistently to produce energy source for this hybrid system compare to PV system. When the wind system does not fully operate due to inconsistent energy source, the other system which is PV will operate and supply the load for equilibrate the extra load demand

  17. Radon Monitoring in Army Stand-Alone Housing Units

    1990-04-01

    damage lung tissue and lead I to increased risk of developing lang cancer . Your risk of developing lung cancer from exposure to radon depends upon the...of developing lung cancer than exposure to a significantly elevated level for a short time. In general, your risk increases as the level of radon and...000mm 0Mmm *000 OOO 0 0w 0 0 000 -0-0 *4 0 880 mama 0 0000000000 000 000Eca ( el cN) 00 9 ’ qqO .00 1(10 0 -U M w co SEE wSS SEES NSEwESO m v MM O v mm

  18. Performance evaluation of stand alone hybrid PV-wind generator

    Nasir, M. N. M.; Saharuddin, N. Z.; Sulaima, M. F.; Jali, Mohd Hafiz; Bukhari, W. M.; Bohari, Z. H.; Yahaya, M. S.

    2015-05-01

    This paper presents the performance evaluation of standalone hybrid system on Photovoltaic (PV)-Wind generator at Faculty of Electrical Engineering (FKE), UTeM. The hybrid PV-Wind in UTeM system is combining wind turbine system with the solar system and the energy capacity of this hybrid system can generate up to charge the battery and supply the LED street lighting load. The purpose of this project is to evaluate the performance of PV-Wind hybrid generator. Solar radiation meter has been used to measure the solar radiation and anemometer has been used to measure the wind speed. The effectiveness of the PV-Wind system is based on the various data that has been collected and compared between them. The result shows that hybrid system has greater reliability. Based on the solar result, the correlation coefficient shows strong relationship between the two variables of radiation and current. The reading output current followed by fluctuate of solar radiation. However, the correlation coefficient is shows moderate relationship between the two variables of wind speed and voltage. Hence, the wind turbine system in FKE show does not operate consistently to produce energy source for this hybrid system compare to PV system. When the wind system does not fully operate due to inconsistent energy source, the other system which is PV will operate and supply the load for equilibrate the extra load demand.

  19. Algal Hydrogen Production -- Stand Alone or Integrated System?

    Ghirardi, Maria L.; Maness, Pin Ching; Kosourovo, Sergey

    2016-01-01

    Photosynthetic bacteria and green algae photoproduce H2. but do so utilizing different catalysts and substrates. Green algae use reductant generate mostly by water oxidation to catalyze the reduction of protons to H2 gas, while photosynthetic bacteria catalyze H2 production from organic acids using the nitrogenase enzyme. Moreover, these two organisms utilize different regions of the solar spectrum to perform photosynthesis: green algae's light harvesting antenna is comprised of chlorophyll molecules that absorb mostly blue and red light; photosynthetic bacteria harvest blue and far-red light through their light-harvesting pigments to run its non-oxygenic photosynthetic reactions. There is thus an opportunity to increase the range of solar spectrum used to photoproduce H2 by combining the light-harvesting and catalytic properties of these two organisms in a single process. In the current manuscript, we describe an experimental system that validates this hypothesis and demonstrates quantitatively the advantages of a two organism process for production of higher amounts of H2 and thus achieving solar light conversion efficiencies.

  20. Deterrents on the Over Utilisation of Stand Alone Photovoltaic (PV ...

    At inception of the programme, systems were either undersized, or over utilised as clients did not reveal their usage needs in an attempt to reduce costs. This resulted in battery failures and other system breakdowns. The NPVREP categorised systems in order to alleviate the problem of under sizing and/or over utilization of ...

  1. Basic Stand Alone Medicare Claims Public Use Files

    U.S. Department of Health & Human Services — CMS is committed to increasing access to its Medicare claims data through the release of de-identified data files available for public use. They contain...

  2. The yeast stands alone: the future of protein biologic production.

    Love, Kerry R; Dalvie, Neil C; Love, J Christopher

    2017-12-22

    Yeasts are promising alternative hosts for the manufacturing of recombinant protein therapeutics because they simply and efficiently meet needs for both platform and small-market drugs. Fast accumulation of biomass and low-cost media reduce the cost-of-goods when using yeast, which in turn can enable agile, small-volume manufacturing facilities. Small, tractable yeast genomes are amenable to rapid process development, facilitating strain and product quality by design. Specifically, Pichia pastoris is becoming a widely accepted yeast for biopharmaceutical manufacturing in much of the world owing to a clean secreted product and the rapidly expanding understanding of its cell biology as a host organism. We advocate for a near term partnership spanning industry and academia to promote open source, timely development of yeast hosts. Copyright © 2017. Published by Elsevier Ltd.

  3. Performance evaluation of stand alone hybrid PV-wind generator

    Nasir, M. N. M.; Saharuddin, N. Z.; Sulaima, M. F.; Jali, Mohd Hafiz; Bukhari, W. M.; Bohari, Z. H. [Faculty of Electrical Engineering, Universiti Teknikal Malaysia Melaka (UTeM), Hang Tuah Jaya, 76100 Melaka (Malaysia); Yahaya, M. S. [Faculty of Engineering Technology, Universiti Teknikal Malaysia Melaka (UTeM), Hang Tuah Jaya, 76100 Melaka (Malaysia)

    2015-05-15

    This paper presents the performance evaluation of standalone hybrid system on Photovoltaic (PV)-Wind generator at Faculty of Electrical Engineering (FKE), UTeM. The hybrid PV-Wind in UTeM system is combining wind turbine system with the solar system and the energy capacity of this hybrid system can generate up to charge the battery and supply the LED street lighting load. The purpose of this project is to evaluate the performance of PV-Wind hybrid generator. Solar radiation meter has been used to measure the solar radiation and anemometer has been used to measure the wind speed. The effectiveness of the PV-Wind system is based on the various data that has been collected and compared between them. The result shows that hybrid system has greater reliability. Based on the solar result, the correlation coefficient shows strong relationship between the two variables of radiation and current. The reading output current followed by fluctuate of solar radiation. However, the correlation coefficient is shows moderate relationship between the two variables of wind speed and voltage. Hence, the wind turbine system in FKE show does not operate consistently to produce energy source for this hybrid system compare to PV system. When the wind system does not fully operate due to inconsistent energy source, the other system which is PV will operate and supply the load for equilibrate the extra load demand.

  4. Basic Stand Alone Medicare Prescription Drug Events PUF

    U.S. Department of Health & Human Services — This is a Public Use File for Prescription Drug Events drawn from the 2008 Beneficiary Summary File of Medicare beneficiaries enrolled during the calendar year 2008,...

  5. PV-Battery Sizing for Stand-Alone Lighting Applications

    Herteleer, Bert; Cappelle, Jan; Appels, Reinhart; Lefevre, Buvana; Driesen, Johan; Catthoor, Francky

    2013-01-01

    This paper presents a follow-up and addition to a system sizing spreadsheet, detailed in [An autonomous photovoltaic system sizing program for office applications in Africa], with a focus on sizing or verifying the employability of an off-grid PV-battery system for night lighting. A dimensionless criterion, the Battery Usable Fraction UF_batt is defined, which aids both the calculations of systems and allows an approximate comparison of batteries, regardless of the employed battery chemistry....

  6. She stands alone: Pakistani woman film director, Shireen Pasha.

    Mustafa, A

    1995-01-01

    This article describes the activities of film director Shireen Pasha in promoting truth in the mass media in Pakistan. Pasha is described as one who finds it inexcusable in a state-subsidized system that national problems of poverty are not aired openly. Pasha has pursued the goal of exposing the real lives of Pakistanis on film in contrast to the publicly aired segments of "pretty girls in nice drawing rooms." Foreign channels available through satellite communications technology are viewed by Pasha as inappropriate with regard to people's needs and uncreative. Pakistan began with one channel, PTV, which recently refused to air her documentary on living conditions in Pakistan's rural areas "The Travelogue Pakistan." "The Walled City of Lahore" was her film about life in the old city. Both films poetically depicted the honor of humans and their struggle to stay alive. Some of her documentaries are made to show the value of indigenous skills, centuries old know-how, and traditions, regardless of the poverty. Pasha is described as fighting with PTV management over use of resources. Pasha desires to invest in training people to do documentaries or be more field-oriented rather than investing in equipment. Pasha joined PTV in 1975 and left in 1990. Pasha is recognized for her isolation as a woman in the business world, her commitment to exposing remote cultures and truth, and the odds she must confront in attaining her goals. Pasha is committed to doing extensive research, usually conducted during the summer months, in order to construct a credible story line that is produced usually during the winter months. One model of film story line is defined as one where women are portrayed as starting from an indigenous skill or knowledge and shifting to a greater position of power and control over their lives. Pasha believes that people who make films have the responsibility to evoke a reaction in people and to offer solutions. Two acclaimed films, which were supported by USAID and the government, were "Before It's Too Late" and "Only One Way." Both deal with resource issues and the environment. She is currently director of her own film house, The Film Makers, in Lahore. After graduating from the National College of Arts in 1968, she furthered her education in the US in the history of art.

  7. Constraining lidar stand-alone retrievals with lunar photometry measurements

    Ortiz-Amezcua, Pablo; Luis Guerrero-Rascado, Juan; Antonio Benavent-Oltra, Jose; Román, Roberto; Böckmann, Christine; Alados-Arboledas, Lucas

    2018-04-01

    This study combines atmospheric optical information measured with lidar and nocturnal photometers in order to find configurations that allow for the retrieval of particle microphysical properties without "3+2" lidar setups. It has been carried out using data measured at the EARLINET Granada station during the experimental campaign SLOPE in the framework of ACTRIS-2 project.

  8. 42 CFR 493.1215 - Condition: Hematology.

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Condition: Hematology. 493.1215 Section 493.1215 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES....1215 Condition: Hematology. If the laboratory provides services in the specialty of Hematology, the...

  9. 42 CFR 493.849 - Condition: Hematology.

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Condition: Hematology. 493.849 Section 493.849 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES... These Tests § 493.849 Condition: Hematology. The specialty of hematology, for the purpose of proficiency...

  10. BMC Blood Disorders becomes BMC Hematology: evolving along with the hematology field

    Chap, Christna

    2013-01-01

    This Editorial marks the launch of BMC Hematology, formerly known as BMC Blood Disorders, within the BMC series of journals published by BioMed Central. The scope of BMC Hematology encompasses basic, experimental and clinical research related to hematology. In this Editorial we will discuss the rationale behind this relaunch and how, as an open access journal providing unrestricted and free access to scientific and scholarly work, BMC Hematology will help disseminate research in the hematolog...

  11. Acute hematologic emergencies in oncology

    Kristof, L.

    2012-01-01

    Malignant disease and its treatment are often being complicated by development of serious and at times life-threatening emergencies. Early recognition and treatment of these acute events are important to reduce morbidity and mortality in cancer patients. The following article provides an overview of several hematologic emergencies, which occur due abnormal hemopoiesis (e.g. hyperleukocytosis, anemia, thrombocytopenia), abnormal hemo stasis (e.g. hemorrhage, pulmonary embolism, disseminated intravascular coagulation), or are related to blood products transfusions (transfuse reactions). (author)

  12. [Oral nutritional supplementation in hematologic patients].

    Peñalva, A; San Martín, A; Rosselló, J; Pérez-Portabella, C; Palacios, A; Julià, A; Planas, M

    2009-01-01

    Hematological patients often present anorexia which along with other secondary effects from the chemotherapy and/or radiotherapy treatments compromise their nutritional status. Oral supplementation can aid to fulfill the energy and protein requirements of these patients. Nevertheless, the use of commercial nutritional supplements normally available, is limited by its poor intake. To evaluate the degree of fulfillment of the prescribed supplements and fulfillment of energy requirements, as well as the development of nutritional status in hematological patients hospitalized for treatment with chemotherapy and/or radiotherapy. Prospective, randomized and open study of inpatients at the hematological ward. Patients were randomized sequentially and they were assigned into 3 different nutritional interventions providing: Group 1 (G1), a flavored supplement; Group 2 (G2): a non flavored (neutral) supplement and Group 3 (G3): "kitchen" foods as supplements. Need and amount of nutritional supplements were provided according to the oral intake previously analyzed. Nutritional assessment (at admission and discharge) was based in the Subjective Global Assessment test (SGA), Risk Nutritional Index (RNI) and percentage of lost weight. Both fulfillment of supplement intake and achievement of energetic requirements were analyzed. 125 patients of 51.3 +/- 16.8 years; 45% men and 55% women. 54% lymphoma, 33% leukemia, 8% myeloma and others 4%. Length of stay (LOS): 7.0 +/- 3.6 d. The nutritional assessment done by SGA showed significant negative changes in G2 and G3 (G1: 30% developed malnutrition and 28% improved their nutritional status, p = NS; G2: 50% developed malnutrition against 7% whom improved their nutritional status, p = 0.002; y G3: 37% developed malnutrition against 21% whom improved their nutritional status, p = 0.02). According to RNI, patients evolved negatively from their nutritional state but no significant differences were found within groups (G1, from 81% of

  13. Wind Energy System Time-domain (WEST) analyzers using hybrid simulation techniques

    Hoffman, J. A.

    1979-01-01

    Two stand-alone analyzers constructed for real time simulation of the complex dynamic characteristics of horizontal-axis wind energy systems are described. Mathematical models for an aeroelastic rotor, including nonlinear aerodynamic and elastic loads, are implemented with high speed digital and analog circuitry. Models for elastic supports, a power train, a control system, and a rotor gimbal system are also included. Limited correlation efforts show good comparisons between results produced by the analyzers and results produced by a large digital simulation. The digital simulation results correlate well with test data.

  14. PRELIMINARY STUDY OF HEMATOLOGICAL PARAMETERS IN HERZEGOVINIAN DONKEY

    Dunja Rukavina

    2016-02-01

    Full Text Available Herzegovinian donkey is a very important animal resource of Bosnia and Herzegovina. There have been no works attempted at determining the normal values of hematological parameters of Herzegovinian donkey. For this reason, the objective of the present study was to investigate some hematological parameters in Herzegovinian donkey. The research was performed on 30 apparently healthy donkeys (18 female and 12 male of ages from 1 to 20 years. Blood samples (3 ml were obtained by jugular vein puncture (vena jugularis externa in vacuum tubes with EDTA. The mean value of hematocrit was 29.19 %, hemoglobin concentration 10.6 g/dl, mean corpuscular hemoglobin concentration 36.33 g/dl, white blood cells 9.33 x109/L, granulocytes (109/L 5.45 x109/L, granulocytes (% 59.47%, lymphocyte/monocyte (109/L 3.89 x109/L, lymphocyte/monocyte (% 40.53% and platelet cells 148.97 x109/L. Parameters were determined using an automated analyzer IDEXX QBC VET AutoRead. Data were analyzed by SPSS V 15. All hematological parameters (except platelet cells were consistent with the recommended reference ranges for donkeys, and the values found in literature so far. Platelet cells values were much lower than in the literature for the other donkey breeds and the recommended reference ranges for donkeys. The slight differences found between our results and those reported in the previous works confirm the need for further studies to investigate the reference values of hematological parameters of Herzegovinian donkey. This work is a contribution to the study of hematological parameters of Herzegovinian donkey, and we expect these data to be applied to the further studies.

  15. B-Cell Hematologic Malignancy Vaccination Registry

    2017-12-29

    Monoclonal Gammopathy of Undetermined Significance; Multiple Myeloma; Waldenstrom Macroglobulinemia; Lymphocytosis; Lymphoma, Non-Hodgkin; B-Cell Chronic Lymphocytic Leukemia; Hematological Malignancies

  16. 21 CFR 864.5680 - Automated heparin analyzer.

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Automated heparin analyzer. 864.5680 Section 864.5680 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES HEMATOLOGY AND PATHOLOGY DEVICES Automated and Semi-Automated Hematology Devices § 864...

  17. Hematological findings in Noonan syndrome

    Bertola Débora R.

    2003-01-01

    Full Text Available OBJECTIVE: Noonan syndrome is a multiple congenital anomaly syndrome, and bleeding diathesis is considered part of the clinical findings. The purpose of this study was to determine the frequency of hemostatic abnormalities in a group of Noonan syndrome patients. METHOD: We studied 30 patients with clinical diagnosis of Noonan syndrome regarding their hemostatic status consisting of bleeding time, prothrombin time, activated partial thromboplastin time and thrombin time tests, a platelet count, and a quantitative determination of factor XI. RESULTS: An abnormal laboratory result was observed in 9 patients (30%. Although coagulation-factor deficiencies, especially factor XI deficiency, were the most common hematological findings, we also observed abnormalities of platelet count and function in our screening. CONCLUSIONS: Hemostatic abnormalities are found with some frequency in Noonan syndrome patients (30% in our sample. Therefore, we emphasize the importance of a more extensive hematological investigation in these patients, especially prior to an invasive procedure, which is required with some frequency in this disorder.

  18. Chemotherapy and Cardiotoxicity in Hematologic Malignancies.

    Stellitano, Antonio; Fedele, Roberta; Barilla, Santina; Iaria, Antonino; Rao, Carmelo Massimiliano; Martino, Massimo

    2017-01-01

    Antineoplastic agents affect the cardiovascular system, and the incidence of cardiotoxicity is continuously growing in patients with hematologic malignancies and treated with antineoplastic therapy. In this mini-review, we analyzed existing literature which evaluates the likelihood of cardiotoxicity related to the main agents employed in the treatment of hematologic malignancies. There is a significant need to optimize the early identification of patients who are at risk of cardiotoxicity. The conventional echocardiographic measurements used to detect cardiac alterations, such as LVEF, fractional shortening, diameters and volumes, allow only a late diagnosis of cardiac dysfunction, which might be already irreversible. The early identification of patients at risk for rapid progression towards irreversible cardiac failure has a primary purpose, the opportunity for them to benefit from early preventive and therapeutic measures. A useful imaging technique that points in this direction detecting subclinical LVD may be the speckle tracking echocardiography, that has demonstrated a previous detection of myocardial contractile dysfunction compared to the traditional left ventricular ejection fraction. In this view, the discovery of new biomarkers to identify patients at a high risk for the development of these complications is another priority. Cardiotoxicity induced by anticancer drugs is always the outcome of several concurrent factors. It is plausible that an asymptomatic dysfunction precedes clinical events. During this asymptomatic phase, an early treatment prepares the patient for cardiovascular "safety" conditions; on the other hand, a late or missing treatment paves the ground for the development of future cardiac events. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  19. Association between the ABO locus and hematological traits in Korean

    Hong Kyung-Won

    2012-09-01

    Full Text Available Abstract Background Recently, genome-wide association studies identified a pleiotropic gene locus, ABO, as being significantly associated with hematological traits. To confirm the effects of ABO on hematological traits, we examined the link between the ABO locus and hematological traits in Korean population-based cohorts. Results Six tagging SNPs for ABO were analyzed with regard to their effects on hematological traits [white blood cell count (WBC, red blood cell count (RBC, platelet (Plat, mean corpuscular volume (MCV, and mean corpuscular haemoglobin concentration (MCHC]. Linear regression analyses were performed, controlling for recruitment center, sex, and age as covariates. Of the 6 tagging SNPs, 3 (rs2073823, rs8176720, and rs495828 and 3 (rs2073823, rs8176717, and rs687289 were significantly associated with RBC and MCV, respectively (Bonferroni correction p-value criteria r2s = 0.99. Of the remaining 3 SNPs (rs8176720, rs8176717 and rs687289, rs8176717 generated an independent signal with moderate p-value (= 0.045 when it was adjusted for by rs2073823 (the most significant SNP. We also identified a copy number variation (CNV that was tagged by the SNP rs8176717, the minor allele of which correlated with the deletion allele of CNV. Our haplotype analysis indicated that the haplotype that contained the CNV deletion was significantly associated with MCV (β ± se = 0.363 ± 0.118, p =2.09 × 10-3. Conclusions Our findings confirm that ABO is one of the genetic factors that are associated with hematological traits in the Korean population. This result is notable, because GWASs fail to evaluate the link between a CNV and phenotype traits.

  20. BMC Blood Disorders becomes BMC Hematology: evolving along with the hematology field.

    Chap, Christna

    2013-04-10

    This Editorial marks the launch of BMC Hematology, formerly known as BMC Blood Disorders, within the BMC series of journals published by BioMed Central. The scope of BMC Hematology encompasses basic, experimental and clinical research related to hematology. In this Editorial we will discuss the rationale behind this relaunch and how, as an open access journal providing unrestricted and free access to scientific and scholarly work, BMC Hematology will help disseminate research in the hematology field in a freely-accessible manner.

  1. Some hematological and biochemical parameters in smokeless ...

    AJB SERVER

    2007-01-04

    Jan 4, 2007 ... The effect of Jharda powder (smokeless tobacco) on some hematological and biochemical parameters in consumers was investigated. Hematological parameters including hemoglobin content and white blood cell and leukocyte counts were higher in jharda powder consumers, while monocytes and.

  2. Some hematological and biochemical parameters in smokeless ...

    The effect of Jharda powder (smokeless tobacco) on some hematological and biochemical parameters in consumers was investigated. Hematological parameters including hemoglobin content and white blood cell and leukocyte counts were higher in jharda powder consumers, while monocytes and basophiles counts were ...

  3. 42 CFR 493.851 - Standard; Hematology.

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Standard; Hematology. 493.851 Section 493.851 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES... These Tests § 493.851 Standard; Hematology. (a) Failure to attain a score of at least 80 percent of...

  4. 42 CFR 493.1269 - Standard: Hematology.

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Standard: Hematology. 493.1269 Section 493.1269 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES... Systems § 493.1269 Standard: Hematology. (a) For manual cell counts performed using a hemocytometer— (1...

  5. 15th Congress of European Hematology Association

    Chomienne, Christine; Guenova, Margarita; Hagenbeek, Antony; Lacombe, Catherine; McCann, Shaun; Foa, Robin

    2010-01-01

    Each year the annual congress of the European Hematology Association gathers clinicians, biologists and scientists dedicated to all fields of hematology. This year's Congress was held in Barcelona, Spain, and presented an appealing program with experts presenting state-of-the-art sessions to more

  6. Skylab experiment results: Hematology studies

    Kimzey, S. L.; Ritzmann, S. E.; Mengel, C. E.; Fischer, C. L.

    1975-01-01

    Studies were conducted to evaluate specific aspects of man's immunologic and hematologic systems that might be altered by or respond to the space flight environment. Biochemical functions investigated included cytogenetic damage to blood cells, immune resistance to disease, regulation of plasma and red cell volumes, metabolic processes of the red blood cell, and physicochemical aspects of red blood cell function. Measurements of hematocrit value showed significant fluctuations postflight, reflecting observed changes in red cell mass and plasma volume. The capacity of lymphocytes to respond to an in vitro mitogenic challenge was repressed postflight, and appeared to be related to mission duration. Most other deviations from earth function in these systems were minor or transient.

  7. Alternative route of process modification for biofuel production by embedding the Fischer–Tropsch plant in existing stand-alone power plant (10 MW) based on biomass gasification – Part I: A conceptual modeling and simulation approach (a case study in Thailand)

    Hunpinyo, Piyapong; Cheali, Peam; Narataruksa, Phavanee; Tungkamani, Sabaithip; Chollacoop, Nuwong

    2014-01-01

    Graphical abstract: SynBiofuel production through existing gasification plants in Thailand, using waste agricultural biomass as raw material, was studied. The process design was initiated conceptually in the areas of gas phase reaction system via Fischer-Tropsch (FT) synthesis. The development of FT configurations on syngas conversion to transportation fuels (e.g., diesel range) was investigated. In order to develop a techno-economic assessment, the three different capacities corresponding to 1 MW, 2 MW and 3 MW based on thermal input of syngas were evaluated. Once-through FT concept was proposed in which the unconverted syngas was combusted with air in an externally fired gas turbine (EFGT) to produce surplus electricity. The results of process simulation were discussed open-mindedly including the overall plant design and energy efficiency. Preliminary economics, and some site specific situations under which additional capital cost savings on existing infrastructure was realized. - Highlights: • Experimental results were used and integrated with a reactor model for SynBiofuel. • Process simulation with the lumped reaction rate was used to achieve accurate results. • Process simulation was performed using ASPEN Plus to design FT configurations. • Maximum energy FT efficiency was approximately 37%. • Economic potential was computed by ROI and PBP resulting in the attractive solutions. - Abstract: The utilization of syngas shows a highly potential to improve the economic potential of the stand-alone power unit-based gasification plants as well as enhancing the growing demand of transportation fuels. The thermochemical conversion of biomass via gasification to heat and power generations from the earlier study is further enhanced by integrating Fischer–Tropsch (FT) synthesis with the existing gasification pilot scale studied previously. To support the potential and perspectives in major economies due to scaling up in developing countries such as Thailand

  8. Can dosimetric parameters predict acute hematologic toxicity in rectal cancer patients treated with intensity-modulated pelvic radiotherapy?

    Wan, Juefeng; Liu, Kaitai; Li, Kaixuan; Li, Guichao; Zhang, Zhen

    2015-01-01

    To identify dosimetric parameters associated with acute hematologic toxicity (HT) in rectal cancer patients undergoing concurrent chemotherapy and intensity-modulated pelvic radiotherapy. Ninety-three rectal cancer patients receiving concurrent capecitabine and pelvic intensity-modulated radiation therapy (IMRT) were analyzed. Pelvic bone marrow (PBM) was contoured for each patient and divided into three subsites: lumbosacral spine (LSS), ilium, and lower pelvis (LP). The volume of each site receiving 5–40 Gy (V 5, V10, V15, V20, V30, and V40, respectively) as well as patient baseline clinical characteristics was calculated. The endpoint for hematologic toxicity was grade ≥ 2 (HT2+) leukopenia, neutropenia, anemia or thrombocytopenia. Logistic regression was used to analyze correlation between dosimetric parameters and grade ≥ 2 hematologic toxicity. Twenty-four in ninety-three patients experienced grade ≥ 2 hematologic toxicity. Only the dosimetric parameter V40 of lumbosacral spine was correlated with grade ≥ 2 hematologic toxicity. Increased pelvic lumbosacral spine V40 (LSS-V40) was associated with an increased grade ≥ 2 hematologic toxicity (p = 0.041). Patients with LSS-V40 ≥ 60 % had higher rates of grade ≥ 2 hematologic toxicity than did patients with lumbosacral spine V40 < 60 % (38.3 %, 18/47 vs.13 %, 6/46, p =0.005). On univariate and multivariate logistic regression analysis, lumbosacral spine V40 and gender was also the variable associated with grade ≥ 2 hematologic toxicity. Female patients were observed more likely to have grade ≥ 2 hematologic toxicity than male ones (46.9 %, 15/32 vs 14.8 %, 9/61, p =0.001). Lumbosacral spine -V40 was associated with clinically significant grade ≥ 2 hematologic toxicity. Keeping the lumbosacral spine -V40 < 60 % was associated with a 13 % risk of grade ≥ 2 hematologic toxicity in rectal cancer patients undergoing concurrent chemoradiotherapy

  9. The Importance of Hematological Parameters in Acute Respiratory Viral Infections in Children

    L. A. Alekseeva

    2013-01-01

    Full Text Available Hematological studies are basic and mandatory in diagnostics and laboratory monitoring of infectious diseases, which led to their inclusion in the modern standards of laboratory examinations of children. Assessment of hematological parameters used for the provisional differential diagnosis of viral or bacterial nature of the disease. For research currently being used increasingly Hematology analyzers, which allows to facilitate and standardize the results. In this paper a comparison and differences hematological parameters practically healthy children and children with respiratory infections. Identified some changes in indicators of haemogram depending on the etiology and character of the clinical course of the disease. On the basis of the leukocyte formula defined leukocyte indices of intoxication and illustrates their importance in assessing the severity of the infection process.

  10. Main hematological parameters of sturgeon species (Acipenseridae (review

    M. Simon

    2017-03-01

    Full Text Available Purpose. To analyze scientific sources on the physiological, biochemical, ecological and genetic features of the main hematological paremeters and patterns of their variability in sturgeon species (Acipenseridae. To examine the fundamental aspects of lipid and protein metabolism in blood serum and the effect of biotic and abiotic factors on them. To highlight the common features of serum enzymes. Findings. A review of scientific papers revealed that although hematological parameters of sturgeons are generally similar to those of teleosts and mammals, there are a number of significant differences. In addition, many hematological parameters are characterized by species specificity, even within a family. Special attention is given to the variability of hematological parameters under the effect of factors of both internal and external environment. The paper describes the effects of sex and age, as well as the seasons of the year on the compositio of sturgeon blood. The fundamentals of the use of serum proteins in genetic and population studies are outlined. The features of the functioning of hemoglobin in sturgeon’s red blood cells are examined. The main hematological parameters involved in the formation and maturation of sexual products, and their effect on fertility are reviewed. For example, the spawners, which hadn’t put reproductive product, are characterized by a low rate of hemoglobin, increase in erythrocyte sedimentation speed and also a rise of the level of crude protein in blood and β-lipoproteid serum.The biochemical parameters (total protein and fractions, glucose, creatinine, cholesterol, the activity of some enzymes (alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, creatine kinase in serum are examined. Practical value. The systematized data on the main hematological parameters and patterns of their variability in sturgeon species will be useful for both scientits and fish farmers. This is due to the

  11. Programmable calculator: alternative to minicomputer-based analyzer

    Hochel, R.C.

    1979-01-01

    Described are a number of typical field and laboratory counting systems that use standard stand-alone multichannel analyzers (MCA) interfaced to a Hewlett-Packard Company (HP 9830) programmable calculator. Such systems can offer significant advantages in cost and flexibility over a minicomputyr-based system. Because most laboratories tend to accumulate MCA's over the years, the programmable calculator also offers an easy way to upgrade the laboratory while making optimum use of existing systems. Software programs are easily tailored to fit a variety of general or specific applications. The only disadvantage of the calculator vs a computer-based system is in speed of analyses; however, for most applications this handicap is minimal. Applications discussed give a brief overview of the power and flexibility of the MCA-calculator approach to automated counting and data reduction

  12. Determinants of hematology-oncology trainees' postfellowship career pathways with a focus on nonmalignant hematology

    Jenkins, Sarah; Mikhael, Joseph; Gitlin, Scott D.

    2018-01-01

    Nonmalignant hematologic conditions are extremely prevalent and contribute significantly to the global burden of disease. The US health care system may soon face a shortage of specialists in nonmalignant hematology. We sought to identify factors that lead hematology-oncology fellows to pursue (or not to pursue) careers in nonmalignant hematology. Cross-sectional, web-based survey distributed to 149 graduates of a hematology-oncology fellowship program at a large academic medical center between 1998 and 2016. Eighty-six out of 149 graduates responded (57.7%); most (59 [68.6%]) practice at an academic medical center. Respondents spend a mean of 61% of their time in clinical practice, 23.7% conducting research, 5.2% in education, and 5.2% in administration. Those in clinical practice spend a mean of 52.1% of their time in solid tumor oncology, 37.5% in hematologic malignancies, and 10% in nonmalignant hematology; only 1 spent >50% of time practicing nonmalignant hematology. Factors most significantly affecting choice of patient population included clinical experience during fellowship and intellectual stimulation of the patient population/disease type. Factors that could have most significantly influenced a decision to spend more time in nonmalignant hematology included increased exposure/access to role models and mentors and opportunities for better career growth/advancement. Fellowship graduates spend >50% of their time in clinical practice, but almost none spend a significant amount of time practicing nonmalignant hematology. Given the growing number of patients with nonmalignant hematologic conditions and a possible future provider shortage, medical trainees should be encouraged to pursue careers in nonmalignant hematology. PMID:29463548

  13. 21 CFR 864.8625 - Hematology quality control mixture.

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Hematology quality control mixture. 864.8625 Section 864.8625 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES HEMATOLOGY AND PATHOLOGY DEVICES Hematology Reagents § 864.8625 Hematology...

  14. DCB - Cancer Immunology, Hematology, and Etiology Research

    Part of NCI’s Division of Cancer Biology’s research portfolio, studies supported include the characterization of basic mechanisms relevant to anti-tumor immune responses and hematologic malignancies.

  15. Invasive Aspergillosis in Hematological Patients.

    Kimura, Shun-Ichi

    2016-01-01

    Invasive aspergillosis (IA) is still one of the leading causes of morbidity and mortality in hematological patients, although its outcome has been improving. Prolonged and profound neutropenia in patients receiving intensive chemotherapy for acute leukemia and stem cell transplantation is a major risk factor for IA. Allogeneic stem cell transplant recipients with graft-versus-host disease and corticosteroid use are also at high risk. Management in a protective environment with high efficiency particular air (HEPA) filter is generally recommended to prevent aspergillosis in patients with prolonged and profound neutropenia. Antifungal prophylaxis against Aspergillus species should be considered in patients with past history of aspergillosis or colonization of Aspergillus species, at facilities with high incidence of IA and those without a protective environment. Early diagnosis and prompt antifungal treatment is important to improve outcome. Imaging studies such as computed tomography and biomarkers such as galactomannan antigen and β-D-glucan are useful for early diagnosis. Empirical antifungal treatment based on persistent or recurrent fever during neutropenia despite broad-spectrum antibiotic therapy is generally recommended in high-risk patients. Alternatively, a preemptive treatment strategy has recently been proposed in the context of progress in the early diagnosis of IA based on the results of imaging studies and biomarkers. Voriconazole is recommended for initial therapy for IA. Liposomal amphotericin B is considered as alternative initial therapy. Combination antifungal therapy of echinocandin with voriconazole or liposomal amphotericin B could be a choice for refractory cases.

  16. The european hematology association roadmap for european hematology research : A consensus document

    A. Engert (Andreas); C.L. Balduini (Carlo); A. Brand (Anneke); B. Coiffier (Bertrand); C. Cordonnier (Charlotte); H. Döhner (Hartmut); De Wit, T.D. (Thom Duyvené); Eichinger, S. (Sabine); W.E. Fibbe (Willem); Green, T. (Tony); De Haas, F. (Fleur); A. Iolascon (Achille); T. Jaffredo (Thierry); F. Rodeghiero (Francesco); G. Salles (Gilles); J.J. Schuringa (Jan Jacob)

    2016-01-01

    textabstractThe European Hematology Association (EHA) Roadmap for European Hematology Research highlights major achievements in diagnosis and treatment of blood disorders and identifies the greatest unmet clinical and scientific needs in those areas to enable better funded, more focused European

  17. Oral microflora in children with hematologic malignancies

    M. F. Vecherkovskaya

    2015-01-01

    Full Text Available The goal was a comprehensive study of oral microflora in healthy children and those with hematologic malignancies, based on the analysis of mixed microbial biofilms composition, isolation and identification of new previously unknown microorganisms. The material was obtained in children with hematological diseases in remission, 2–10 years aged, and for the control group from St. Petersburg schoolchildren and in kindergartens. We used microbiological, biochemical and molecular genetic methods, including electron microscopy, proteomic analysis, sequencing and complete genome annotation. Microorganisms of 23 genera isolated as pure cultures and identified by biochemical activity from mixed microbial biofilm derived from saliva of healthy and sick children. In microflora of children with hematologic malignancies a previously unknown type of streptococci with a large number of antibiotic resistance genes was revealed. Differences in oral microbiota composition of healthy children and children with hematological diseases in remission were revealed. The microbiota of children with hematologic malignancies contains more genes controlling antibiotic resistance. Also, it was observed previously unknown bacterium of the genus Streptococcus.

  18. Oral microflora in children with hematologic malignancies

    M. F. Vecherkovskaya

    2015-06-01

    Full Text Available The goal was a comprehensive study of oral microflora in healthy children and those with hematologic malignancies, based on the analysis of mixed microbial biofilms composition, isolation and identification of new previously unknown microorganisms. The material was obtained in children with hematological diseases in remission, 2–10 years aged, and for the control group from St. Petersburg schoolchildren and in kindergartens. We used microbiological, biochemical and molecular genetic methods, including electron microscopy, proteomic analysis, sequencing and complete genome annotation. Microorganisms of 23 genera isolated as pure cultures and identified by biochemical activity from mixed microbial biofilm derived from saliva of healthy and sick children. In microflora of children with hematologic malignancies a previously unknown type of streptococci with a large number of antibiotic resistance genes was revealed. Differences in oral microbiota composition of healthy children and children with hematological diseases in remission were revealed. The microbiota of children with hematologic malignancies contains more genes controlling antibiotic resistance. Also, it was observed previously unknown bacterium of the genus Streptococcus.

  19. Musculoskeletal Imaging Findings of Hematologic Malignancies.

    Navarro, Shannon M; Matcuk, George R; Patel, Dakshesh B; Skalski, Matthew; White, Eric A; Tomasian, Anderanik; Schein, Aaron J

    2017-01-01

    Hematologic malignancies comprise a set of prevalent yet clinically diverse diseases that can affect every organ system. Because blood components originate in bone marrow, it is no surprise that bone marrow is a common location for both primary and metastatic hematologic neoplasms. Findings of hematologic malignancy can be seen with most imaging modalities including radiography, computed tomography (CT), technetium 99m ( 99m Tc) methylene diphosphonate (MDP) bone scanning, fluorine 18 ( 18 F) fluorodeoxyglucose (FDG) positron emission tomography (PET)/CT, and magnetic resonance (MR) imaging. Because of the diversity of imaging appearances and clinical behavior of this spectrum of disease, diagnosis can be challenging, and profound understanding of the underlying pathophysiologic changes and current treatment modalities can be daunting. The appearance of normal bone marrow at MR imaging and FDG PET/CT is also varied due to dynamic compositional changes with normal aging and in response to hematologic demand or treatment, which can lead to false-positive interpretation of imaging studies. In this article, the authors review the normal maturation and imaging appearance of bone marrow. Focusing on lymphoma, leukemia, and multiple myeloma, they present the spectrum of imaging findings of hematologic malignancy affecting the musculoskeletal system and the current imaging tools available to the radiologist. They discuss the imaging findings of posttreatment bone marrow and review commonly used staging systems and consensus recommendations for appropriate imaging for staging, management, and assessment of clinical remission. © RSNA, 2017.

  20. Transient analyzer

    Muir, M.D.

    1975-01-01

    The design and design philosophy of a high performance, extremely versatile transient analyzer is described. This sub-system was designed to be controlled through the data acquisition computer system which allows hands off operation. Thus it may be placed on the experiment side of the high voltage safety break between the experimental device and the control room. This analyzer provides control features which are extremely useful for data acquisition from PPPL diagnostics. These include dynamic sample rate changing, which may be intermixed with multiple post trigger operations with variable length blocks using normal, peak to peak or integrate modes. Included in the discussion are general remarks on the advantages of adding intelligence to transient analyzers, a detailed description of the characteristics of the PPPL transient analyzer, a description of the hardware, firmware, control language and operation of the PPPL transient analyzer, and general remarks on future trends in this type of instrumentation both at PPPL and in general

  1. Hematological Parameters in the Volatile Substance Sniffers

    Dündaröz, Ruşen; Ceylan, Süleyman; Denli, Metin; Açıkel, Cengizhan; Balım, Elvan; Özışık, Tahir

    2009-01-01

    SüleymanDemirel Üniversitesi TIP FAKÜLTESİ DERGİSİ: 1999 Eylül; 6(3) Hematological Parameters in the Volatile Substance Sniffers Ruşen Dündaröz, Süleyman Ceylan, Metin Denli, Cengiz Han Açıkel, Elvan Balım, Tahir Özışık Abstract Glue sniffing is a frequent problem among teenagers. Various chemical substances, especially toluene and benzene, contained in the glues kave been reported to be hematotoxic. The hematological parameters of 44 healthy teenagers ~...

  2. The European Hematology Association Roadmap for European Hematology Research: a consensus document.

    Engert, Andreas; Balduini, Carlo; Brand, Anneke; Coiffier, Bertrand; Cordonnier, Catherine; Döhner, Hartmut; de Wit, Thom Duyvené; Eichinger, Sabine; Fibbe, Willem; Green, Tony; de Haas, Fleur; Iolascon, Achille; Jaffredo, Thierry; Rodeghiero, Francesco; Salles, Gilles; Schuringa, Jan Jacob

    2016-02-01

    The European Hematology Association (EHA) Roadmap for European Hematology Research highlights major achievements in diagnosis and treatment of blood disorders and identifies the greatest unmet clinical and scientific needs in those areas to enable better funded, more focused European hematology research. Initiated by the EHA, around 300 experts contributed to the consensus document, which will help European policy makers, research funders, research organizations, researchers, and patient groups make better informed decisions on hematology research. It also aims to raise public awareness of the burden of blood disorders on European society, which purely in economic terms is estimated at €23 billion per year, a level of cost that is not matched in current European hematology research funding. In recent decades, hematology research has improved our fundamental understanding of the biology of blood disorders, and has improved diagnostics and treatments, sometimes in revolutionary ways. This progress highlights the potential of focused basic research programs such as this EHA Roadmap.The EHA Roadmap identifies nine 'sections' in hematology: normal hematopoiesis, malignant lymphoid and myeloid diseases, anemias and related diseases, platelet disorders, blood coagulation and hemostatic disorders, transfusion medicine, infections in hematology, and hematopoietic stem cell transplantation. These sections span 60 smaller groups of diseases or disorders.The EHA Roadmap identifies priorities and needs across the field of hematology, including those to develop targeted therapies based on genomic profiling and chemical biology, to eradicate minimal residual malignant disease, and to develop cellular immunotherapies, combination treatments, gene therapies, hematopoietic stem cell treatments, and treatments that are better tolerated by elderly patients. Copyright© Ferrata Storti Foundation.

  3. Weights, hematology and serum chemistry of free-ranging brown boobies (Sula leucogaster) in Johnston Atoll, Central Pacific

    Work, Thierry M.

    1999-01-01

    Hematologic and serum chemistry values are reported for 105 brown boobies (Sula leucogaster) from Johnston Atoll, Central Pacific. Hematocrit, estimated total plasma solids, total and differential white cell counts, serum glucose, calcium, phosphorus, uric acid, total protein, albumin, globulin, aspartate aminotransferase, and creatinine phosphokinase were analyzed. Hematologic and serum chemistry values varied with age and sex. Values were compared with those of red-footed boobies and other tropical and temperate marine pelecaniforms.

  4. Fertility considerations in young women with hematological malignancies

    Jadoul, Pascale; Kim, S Samuel; Andersen, Claus Yding

    2012-01-01

    The need for practice guidelines for fertility preservation in young women with hematological malignancies has been increased. To develop recommendations, publications relevant to fertility preservation and hematological cancers were identified through a PubMed database search and reviewed...

  5. Hematological and Serum Biochemical Parameters of Weanling ...

    The objective of this study was to determine the dose-dependent effect of medroxyprogesterone acetate on hematology and serum biochemistry in weanling dogs. Nine healthy local dogs between 12 to 14 weeks of age were randomly assigned to three treatments: control, 150mg/kg and 300mg/kg of medroxyprogesterone ...

  6. Neutropenia in pediatric hematology/oncology practice

    E. A. Deordieva

    2015-06-01

    Full Text Available Acquired neutropenia is one of the most common conditions in pediatric hematology practice. These conditions usually are benign. In contrast, congenital neutropenia are rare conditions, but in the absence of pathogenic therapy can cause fatal complications. Approach to the differential diagnosis and management of these patients are discussed in this review.

  7. Growth performance, carcass and hematological characteristics of ...

    Growth performance, carcass and hematological characteristics of rabbits fed graded levels of tiger nuts ( Cyperus esculentus ) ... (p>0.05) difference between treatments. Results demonstrated that (Cyperus esculentus) could be used up to 5% in rabbit's diets without adverse effect on the animals' performance and health.

  8. Effects of maternal dexamethasone exposure on hematological ...

    Exposure to dexamethasone at LD 1-14 and 1-21 significantly (P<0.05) reduced RBC and platelet counts but it raised MCV and MCH relative to control. This study suggests that prenatal and lactational dexamethasone administration may affect the hematological indices in the male offspring. Keywords: Dexamethasone ...

  9. Performance, immunity, serum biochemical and hematological ...

    ... results suggest that supplementing broilers' diet with 5 g/kg thyme can indicate favorable influences of antibiotic growth promoter on performance without any detrimental impacts on immune responses and blood parameters. Key words: Broiler, thyme, growth performance, immunity, serum biochemistry, hematology.

  10. Bacteremia and candidemia in hematological malignancies

    Hovgaard, D; Skinhøj, P; Bangsborg, Jette Marie

    1988-01-01

    171 episodes of bacteremia and candidemia in 142 patients were recorded during the period 1981-1985 in patients with hematological malignancies. Overall mortality, within 1 week of onset of bacteremia, was 20%. Increased mortality was found in patients with poor disease-prognosis (39%), with gran...

  11. Survival From Childhood Hematological Malignancies in Denmark

    Erdmann, Friederike; Winther, Jeanette Falck; Dalton, Susanne Oksbjerg

    2016-01-01

    BACKGROUND: Due to diverse findings as to the role of family factors for childhood cancer survival even within Europe, we explored a nationwide, register-based cohort of Danish children with hematological malignancies. METHODS: All children born between 1973 and 2006 and diagnosed with a hematolo...

  12. Hematological outcome in neonatal alloimmune hemolytic disease

    Rath, Mirjam Eva Aafke

    2013-01-01

    This thesis focuses on several aspects related to the hematological outcome of infants with hemolytic disease of the fetus and newborn (HDFN) due to red blood cell alloimmunization, including pathogenesis and management of the disease. The presence of leukocytopenie and thrombocytopenia support the

  13. Hematologic features among anemic Cameroonian pregnant women

    Introduction: iron deficiency anemia is the leading cause of anemia worldwide. It may also be the leading cause of anemia in pregnancy, although this has not yet been demonstrated in our country. The aim of the study was to describe hematologic features of Cameroonian anemic pregnant women. Methods: this cross ...

  14. Pattern of Duplicate Presentations at National Hematology-Oncology Meetings: Influence of the Pharmaceutical Industry.

    Ramchandren, Radhakrishnan; Schiffer, Charles A

    2016-03-01

    The major large US hematology-oncology meetings sponsored by the American Society of Hematology (ASH) and American Society of Clinical Oncology (ASCO) have specific guidelines in place discouraging submission of scientific information presented previously at other meetings. Nonetheless, duplicate submissions are frequent. The incidence and motivations for duplicate hematologic presentations and the influence of the pharmaceutical industry on this process have not been thoroughly analyzed. Therefore, were viewed four consecutive ASH and ASCO meetings to assess the frequency of duplicate abstract presentations. All abstracts presented at ASCO2010 in the area of malignant hematology were compared with abstracts from ASCO and ASH 2009 and ASH 2010, and funding sources were reviewed. More than half (54%) of all abstracts submitted to ASCO 2010 acknowledged pharmaceutical company support. Almost one third (31%) of ASCO 2010 abstracts were resubmitted in the 2-year time period, and it was notable that a high fraction (75%) of these duplicate abstracts had pharmaceutical industry sponsorship, compared with 42% of the abstracts that were submitted only once. Despite current guidelines prohibiting duplicate abstract presentation, a substantial proportion (31%) of abstracts at large international hematology-oncology meetings are duplicative, with potential negative consequences. In addition, a disproportionate percentage of the duplicate abstracts rely on pharmaceutical industry support (75%), suggesting that marketing strategies may be a motivation for some of these repetitive submissions.

  15. Seasonal variations in red deer (Cervus elaphus) hematology related to antler growth and biometrics measurements.

    Gaspar-López, Enrique; Landete-Castillejos, Tomás; Estevez, Jose Antonio; Ceacero, Francisco; Gallego, Laureano; García, Andrés Jose

    2011-04-01

    The aim of the study was to relate seasonal hematology changes with the rest of physiological variations suffered by red deer, such as antler and biometrics cycle, and to assess the relationship between hematology and the effort performed in antler development. Blood samples were taken from 21 male red deer every 4 weeks during 18 months. Samples were analyzed for the main hematological parameters. Simultaneously, biometrics measurements were taken, such as antler length, body weight, body condition score, testicular diameter (TD), and thoracic and neck girth. All the blood cell types (erythrocytes, leukocytes, and platelets) showed seasonal variations, increasing as antler cleaning approached, as did hematocrit and hemoglobin. The final size of antlers was negatively related to leukocyte count, nonlymphoid leukocyte count, red cell distribution width, mean corpuscular hemoglobin, mean platelet volume, and TD, whereas it was positively related to body condition during antler growth. Huge seasonal variations in some hematological values have been found to be related to changes in antler and biometrics measurements. Since these variations are even greater than the caused by deer handling, they should be taken into account when evaluating hematology in deer populations. Copyright © 2011 Wiley-Liss, Inc., A Wiley Company.

  16. Radiometric analyzer

    Arima, S.; Oda, M.; Miyashita, K.; Takada, M.

    1977-01-01

    A radiometric analyzer for measuring the characteristic values of a sample by radiation includes a humer of radiation measuring subsystems having different ratios of sensitivities to the elements of the sample and linearizing circuits having inverse function characteristics of calibration functions which correspond to the radiation measuring subsystems. A weighing adder operates a desirable linear combination of the outputs of the linearizing circuits. Operators for operating between two or more different linear combinations are included

  17. Hematological parameters after acute radiation injury

    Hirashima, Kunitake

    1989-01-01

    According to clinical experiences of radiation accidents during the past two decades, utilization of measured hematologic changes as a direcrt indicator of the severity of radiation injury provides important information for diagnosis and prognostic evaluation in individual cases. Hematologic changes can be described in terms of prognostic categories based on the possible outcome of the acute radiation syndrome. The five categories suggested by Wald according to the grade of severity. By the actual application of this category to our experience of the 1971 Chiba accident of exposure to irridium 192, it was proved that the estimated dose was well correlated to the value by cytogenetic analysis and physical estimation used of thermo-luminescence phenomena. In hematological parameters, a decrease of lymphocytes occurs whithin 24 hours after the exposure. The level of this early lymphopenia is regarded as one of the best indicators of severity of radiation injury. For the decision of therapeutic procedures, however, the total granulocyte count and platelet count are more valuable to exclude severe infection and bleeding symptoms occurred one month after the exposure. The limitation of the approach by hematologic data must exist in the case exposed in a non-uniform fashion. To overwhelm this difficulty, the application of rapid marrow scanning by short-lived RI such as 52 Fe is expected and the bone marrow imaging by magnetic resonance studies is more exciting. For more sensitive and technically easy-drived methods detecting hematologic injury, our new method of detecting micro-nucleus in polychromatic erythroblasts from cultured erythroid colonies from peripheral blood is now developing. Preliminary data have shown the sensitivity of this method is comparable to the cytogenetic study of pheripheral lymphocytes. (author)

  18. Contamination Analyzer

    1994-01-01

    Measurement of the total organic carbon content in water is important in assessing contamination levels in high purity water for power generation, pharmaceutical production and electronics manufacture. Even trace levels of organic compounds can cause defects in manufactured products. The Sievers Model 800 Total Organic Carbon (TOC) Analyzer, based on technology developed for the Space Station, uses a strong chemical oxidizing agent and ultraviolet light to convert organic compounds in water to carbon dioxide. After ionizing the carbon dioxide, the amount of ions is determined by measuring the conductivity of the deionized water. The new technique is highly sensitive, does not require compressed gas, and maintenance is minimal.

  19. Multi-factor analysis on events related to hematological toxicity in 153Sm-EDTMP palliative therapy for skeletal metastases

    Zhan Hongwei; Yu Xiaoling; Ye Xiaojuan; Bao Chengkan; Sun Da; He Gangqiang

    2006-01-01

    Objective: To investigate the clinical factors related to hematological toxicity induced by intravenous samarium-153 ethylenediaminetetramethylene phosphonic acid ( 153 Sm-EDTMP) treatment. Methods A total of 206 patients with bony metastases treated with 153 Sm-EDTMP were retrospectively analyzed. Logistic regression (SPSS 10.0 for Windows) and correlation analysis were used to evaluate the factors concerned. Results: Age of the patient, number of bone metastatic lesion, chemotherapy before 153 Sm-EDTMP therapy, concurrent radiotherapy and repeat-times of 153 Sm-EDTMP treatments were found the individual factors related to hematological toxicity. Chemotherapy before 153 Sm-EDTMP, concurrent radiotherapy, medication for normal blood counting and repeat-times of 153 Sm-EDTMP treatments were the hematological toxicity factors in multi-factor analysis. Conclusion: In 153 Sm-EDTMP therapy, several factors were found related to hematological toxicity suggesting more attention be paid to the change of blood cell counting after the palliative therapy. (authors)

  20. In Vitro Leukoagglutination: A Rare Hematological Cause of Spurious Leukopenia

    Sadia Sultan

    2017-08-01

    Full Text Available Leukopenia secondary to leukocytic agglutination is caused by an ethylene diamine tetra acetic acid (EDTA which may appear in both benign and malignant states. Ethylene diamine tetra acetic acid induced platelets clumping in peripheral blood has been well established, but invitro leukocytic aggregation is very rarest hematological finding. Pseudo-leukopenia resulting from leukoagglutinins has been reported in the cirrhotic state, infections, autoimmune disorders, uremia, in immunosuppressed state or in various malignancies. Though the condition seems to be benign but very important to be detected as these artifactual findings lead to unnecessary investigations and remarkably changed the overall management plan. Here we report the case of a young patient with this rare finding who was admitted to our hospital with progressive labor pains. The analysis of ethylene diaminetetraacetic acid (EDTA, anticoagulated blood was done on automated hematology analyzer reveals leukopenia. The peripheral smear examination revealed multiple aggregates of leukocytes. On repeat sampling in citrate anticoagulant, the complete blood count showed total leukocytic count of 16.5x109/L with absolute neutrophilic count of 11.5x109/L. This is a rare case of spurious leukopenia secondary to in-vitro leukocytic agglutination provoked by EDTA anticoagulant.

  1. Carbamazepine - hematologic effects of the use

    Kamil Leis

    2018-06-01

    Full Text Available Carbamazepine is an antiepileptic drug which exhibits a number of side effects, namely including a headache, abdominal pain, increased blood pressure, but also hematologic disorders. Thrombocytopenia, hypogammaglobulinemia, leukopenia, neutropenia, agranulocytosis, aplastic anemia, pure red cell aplasia, leukemia or eosinophilia with DRESS syndrome belong to the latter. There is a low incidence of carbamazepine pharmacotherapy related symptoms and their exact mechanisms of action are still unknown.

  2. Chromosome dosimetry: its valorization by hematological data

    Le Go, R.; Doloy, M.T.; Malarbet, J.L.; Veyrat, M.

    1979-01-01

    The assessment of radio-induced biological damage is based upon a number of biological disciplines. Amoung these, two show a particular sensitivity and reliability: cytogenetics and hematology. Using these separately, the data are not always sufficient, but the confrontation of their results reduces the uncertainties in such estimations. Indeed, the mechanisms involved in the responses of both systems are different, as are their dynamics. A brief summary of these mechanisms will illustrate their differences as well as their complementarity

  3. Undergraduate hematology – a more integrated approach

    Di Carlofelice MA

    2016-11-01

    Full Text Available Matteo A Di Carlofelice,* Jack FT Cope*Faculty of Medicine, Imperial College London, London, UK*These authors contributed equally to this workAs fellow medical students we read with great interest the article by Mandan et al1 proposing a dedicated hematology rotation. The authors highlight a gap in clinical hematology teaching, particularly compared to “conventional rotations”.1 Their suggestion has merits and we agree with most of the points raised; however, propose instead for us to build on current teaching as opposed to establishing a new rotation.The integration of theoretical and practical learning was concluded to be beneficial to both teacher and student by Wrenn and Wrenn.2 In the original article it is mentioned that “clinical experience allows students to comprehend and apply this knowledge in practice, enabling the all-important integration of their learning”.1 As we agree that hematology overlaps with other specialties and therefore requires a thorough understanding, we value how a clinical attachment would be useful to solidify lecture-based teaching.View the original paper by Mandan et al.

  4. Hematologic syndrome in man modeled from mammalian lethality

    Jones, T.D.

    1981-01-01

    Data on acute radiation lethality due to failure of the hematologic system in rats, mice, dogs, swine, monkeys and man are analyzed. Based on the available data, the mortality incidences for 1-100% levels can be computed directly if one has only an estimate of the dose lethal to 50% of the population (LD 50 ) for the mammalian strain and radiation environment of interest. The sole restriction is that the dose profile to the marrow be moderately uniform. If an LD 50 for any exposure situation has been measured, then one can readily scale to any desired situation through implicit-biological and empirical-physical relationships. The LD 50 for man, exposed to an isotropic cloud of photons, and knowledge of the bone-marrow dose profiles readily permit evaluation of the model for other levels of human mortality from different irradiating particles, partial body irradiation and spatially dependent and/or mixed radiation environments. (author)

  5. Nursing safety management in onco-hematology pediatric wards

    Marcelle Miranda da Silva

    2015-02-01

    Full Text Available This study aimed at identifying how safety management is applied by nurses to manage the nursing care, and at analyzing their challenges in onco-hematology pediatric wards. Descriptive and qualitative research, conducted at the Instituto Estadual de Hematologia Arthur de Siqueira Cavalcanti, Rio de Janeiro, Brazil, in August 2013. Six nurses were interviewed, and the content analysis was used. The key aspects relate to the importance of training and continuing education, teamwork, with the challenges in the care of hospitalized children and particularities of the disease, and the systematization, use of instruments and protocols. For child safety, the relationship between the administration and support is critical to the quality of care.

  6. Baccaurea angulata fruit juice ameliorates altered hematological and biochemical biomarkers in diet-induced hypercholesterolemic rabbits.

    Ahmed, Idris Adewale; Mikail, Maryam Abimbola; Ibrahim, Muhammad

    2017-06-01

    Hypercholesterolemia is an important risk factor linked to the alteration of blood hematology and clinical chemistry associated with the development and progression of atherosclerosis. Previous studies have demonstrated the safety and potential health benefits of Baccaurea angulata (BA) fruit. We hypothesized that the oral administration of BA fruit juice could ameliorate the alteration in the hematological and biochemical biomarkers of diet-induced hypercholesterolemic rabbits. The aim of this study was to investigate the effects of different doses of BA juice on the hematological and biochemical biomarkers in normo- and hypercholesterolemic rabbits. Thirty-five healthy adult New Zealand White rabbits were assigned to seven different groups for 90days of diet intervention. Four atherogenic groups were fed a 1% cholesterol diet and 0, 0.5, 1.0, and 1.5mL of BA juice per kg of rabbit daily. The other three normal groups were fed a commercial rabbit pellet diet and 0, 0.5, and 1.0mL of BA juice per kg of rabbit daily. Baseline and final blood samples after 90days of repeated administration BA juice were analyzed for hematological parameters while serum, aortic and hepatic lysates were analyzed for lipid profiles and other biochemical biomarkers. The alteration of the hemopoietic system, physiological changes in serum and tissues lipid profiles and other biochemicals resulting from the consumption of a high-cholesterol diet were significantly (Pjuice. Improvements of the biomarkers in rabbits were dose-dependent, markedly enhanced at the highest dose of juice (1.5mL/kg/day). The results suggest potential health benefits of the antioxidant-rich BA fruit juice against hypercholesterolemia-associated hematological and biochemical alterations in the rabbit. Copyright © 2017 Elsevier Inc. All rights reserved.

  7. Hematological Manifestation in HIV Infected Children

    Bhowmik, A.; Banerjee, P.

    2015-01-01

    Objective: To determine the common hematological abnormalities in HIV infected children and any association of these abnormalities with HIV disease severity. Study Design: Cross-sectional study. Place and Duration of Study: Regional Pediatric ART centre, Medical College and Hospital, Kolkata, West Bengal, India, from November 2011 to November 2012. Methodology: Children up to 12 years with confirmed diagnosis of HIV infection were clinically examined and tested for complete hemogram and CD4 count. Bone marrow study was done in selected patient depending on hemogram report. Children were divided in different stages according to WHO clinical staging. Each of the hematological parameters was assessed for any association with progression of disease. Fisher's Exact Test was used for determining the association between WHO clinical staging and abnormal blood parameters. P-value < 0.05 was taken as significant. Results: Sixty nine percent of the study population was anemic; 47.37% (18/38), 66.67% (8/12), 71.43% (15/21) and 93.10% (27/29) of stage 1, 2, 3 and 4 respectively were anemic in the study population (p=0.001). Leucopenia was present in 34% (34/100) children. Neutropenia and lymphopenia was present in 19% (19/100) and 22% (22/100) children. Lymphopenia was present in 7.89% (3/38), 16.67% (2/12), 19.05% (4/21) and 44.83% (13/29) of patient with stage 1, 2, 3 and 4 respectively (p=0.020). Eosinophilia was present in 17% (17/100) and thrombocytopenia in 11% (11/100) children. 2 patients with stage 4 disease were with hypoplastic bone marrow. Conclusion: Anemia was the most common hematological abnormality in HIV infected children. Anemia and lymphopenia had a significant association with the stage of the disease. (author)

  8. Hematology of healthy Florida manatees (Trichechus manatus)

    Harvey, J.W.; Harr, K.E.; Murphy, D.; Walsh, M.T.; Nolan, E.C.; Bonde, R.K.; Pate, M.G.; Deutsch, C.J.; Edwards, H.H.; Clapp, W.L.

    2009-01-01

    Background: Hematologic analysis is an important tool in evaluating the general health status of free-ranging manatees and in the diagnosis and monitoring of rehabilitating animals. Objectives: The purpose of this study was to evaluate diagnostically important hematologic analytes in healthy manatees (Trichechus manatus) and to assess variations with respect to location (free ranging vs captive), age class (small calves, large calves, subadults, and adults), and gender. Methods: Blood was collected from 55 free-ranging and 63 captive healthy manatees. Most analytes were measured using a CELL-DYN 3500R; automated reticulocytes were measured with an ADVIA 120. Standard manual methods were used for differential leukocyte counts, reticulocyte and Heinz body counts, and plasma protein and fibrinogen concentrations. Results: Rouleaux, slight polychromasia, stomatocytosis, and low numbers of schistocytes and nucleated RBCs (NRBCs) were seen often in stained blood films. Manual reticulocyte counts were higher than automated reticulocyte counts. Heinz bodies were present in erythrocytes of most manatees. Compared with free-ranging manatees, captive animals had slightly lower MCV, MCH, and eosinophil counts and slightly higher heterophil and NRBC counts, and fibrinogen concentration. Total leukocyte, heterophil, and monocyte counts tended to be lower in adults than in younger animals. Small calves tended to have higher reticulocyte counts and NRBC counts than older animals. Conclusions: Hematologic findings were generally similar between captive and free-ranging manatees. Higher manual reticulocyte counts suggest the ADVIA detects only reticulocytes containing large amounts of RNA. Higher reticulocyte and NRBC counts in young calves probably reflect an increased rate of erythropoiesis compared with older animals. ?? 2009 American Society for Veterinary Clinical Pathology.

  9. Effect of subchronic administration of nutmeg (Myristica fragrans Houtt) ethanolic extract to hematological parameters in rat

    Bachri, M. S.; Yuliani, S.; Sari, A. K.

    2017-11-01

    Nutmeg is dried kernel of broadly ovoid seed of Myristica fragrans Houtt. It has been mentioned in ethnomedical literature as aphrodisiac, stomachic, carminative, tonic, and nervous stimulant. In order to establish the safety of nutmeg, the effect of the repeated administration of nutmeg is needed. The study was aimed to determine the toxic effect of subchronic administration of nutmeg ethanolic extract to hematological parameters in rat. A total of 28 male adult Wistar rats divided into 4 groups. Group I as control was given by 0.5% CMC-suspension, group II, III, and IV were given by 50, 100, and 200 mg/kg bw, respectively, of nutmeg ethanolic extract. The treatments were administered daily for 31 days. On day 31 bloods were taken from orbital sinus. The hematological parameter consisted of the numbers of erythrocyte and leukocyte as well as hemoglobin and total protein levels were measured. The data were statistically analyzed by one way Anova followed by LSD test. All of observed hematological parameters in rats showed that there were no significant difference between the nutmeg ethanolic extract treated groups and control group. The result indicated that the subchronic administration of 50, 100, and 200 mg/kg bw of nutmeg ethanolic extract did not cause the change of hematological parameters in rat.

  10. Cytogenetic and hematological studies in the workers occupationally exposed to low levels of ionizing radiation

    Zakeri, F.; Honarjoo, M.; Rajab pour, M.; Zahadat, A.; Ahmad pour, M.J.; Asghari, K.

    2007-01-01

    Complete text of publication follows. Objective: This study was aimed at detecting both the incidence of chromosomal aberrations and changes in the hematological parameters as biomarkers of possible radiation injury among workers occupationally exposed to low levels of ionizing radiation and detecting the dose-effect relationship. Methods: Samples of peripheral blood were collected from 38 male industrial radiographers exposed to ionizing radiation for 1-16 years and from 24 age- and sex-matched healthy blood donors without radiation history served as control group. All radiation workers were routinely monitored with film badge. Cytogenetic analysis in peripheral blood lymphocytes assessed by the conventional chromosome aberration assay and at least 200 metaphases for each person were scored. The collected blood samples were analyzed for hematological assay using an automatic analyzer Sysmex KX-21, where 14 different parameters were computerized. Mann-Whitney U test was used to compare the frequencies of the unstable aberrations and hematological parameters between test and control groups. Dose-effect relationship and the influence of age and duration of employment was tested by regression analysis. Results and conclusion: The mean frequencies of dicentric and acentric chromosome aberrations were significantly higher in the exposed group than in the control group (P< 0.0005). No correlation between chromosomal aberrations and physical dose and age was observed in the exposed group. Also there is no clear relation between chromosome damage and duration of exposure. However, the increase in chromosome aberrations in the exposed group was not followed by a corresponding hematological depression. The average values of hematological indices were within the reference levels and did not show any significant differences with control group. A tendency of decreasing the absolute lymphocyte count within the referential levels was the only hematological effect in radiation

  11. Pancytopenia: A clinico-hematological study

    Fahim Manzoor

    2014-01-01

    Full Text Available Background: A review of both Western and Indian literature shows that there are few comprehensive studies on pancytopenia. In India, the causes of pancytopenia are not well defined. This data, if available, would help in planning the diagnostic and therapeutic approach in patients with pancytopenia. Aim: To evaluate the cases of pancytopenia by peripheral smear and/or bone marrow aspiration and/or bone marrow biopsy to find out the etiology, clinical, hematological, and histomorphologic features of pancytopenia. Materials and Methods: Detailed hematological investigations a complete hemogram, peripheral smear examination, bone marrow aspiration, and biopsy examination were done. Results: The most common cause of pancytopenia in our study was megaloblastic anemia (56%, followed by hypoplastic/aplastic anemia (14%, hypersplenism (8% and post viral illness (6%. Conclusion: Megaloblastic anemia due to vitamin B12/folate deficiency seems to reflect the higher prevalence of pancytopenia in Indian subjects, putting hypoplastic/aplastic anemia in the second position, which is the leading cause for pancytopenia in the Western countries.

  12. The PIM kinases in hematological cancers.

    Alvarado, Yesid; Giles, Francis J; Swords, Ronan T

    2012-02-01

    The PIM genes represent a family of proto-oncogenes that encode three different serine/threonine protein kinases (PIM1, PIM2 and PIM3) with essential roles in the regulation of signal transduction cascades, which promote cell survival, proliferation and drug resistance. PIM kinases are overexpressed in several hematopoietic tumors and support in vitro and in vivo malignant cell growth and survival, through cell cycle regulation and inhibition of apoptosis. PIM kinases do not have an identified regulatory domain, which means that these proteins are constitutively active once transcribed. They appear to be critical downstream effectors of important oncoproteins and, when overexpressed, can mediate drug resistance to available agents, such as rapamycin. Recent crystallography studies reveal that, unlike other kinases, they possess a hinge region, which creates a unique binding pocket for ATP, offering a target for an increasing number of potent small-molecule PIM kinase inhibitors. Preclinical studies in models of various hematologic cancers indicate that these novel agents show promising activity and some of them are currently being evaluated in a clinical setting. In this review, we profile the PIM kinases as targets for therapeutics in hematologic malignancies.

  13. Hematological changes in opium addicted diabetic rats.

    Asadikaram, Gholamreza; Sirati-Sabet, Majid; Asiabanha, Majid; Shahrokhi, Nader; Jafarzadeh, Abdollah; Khaksari, Mohammad

    2013-01-01

    Chronic opioid treatment in animal models has shown to alter hematological parameters. The aim of this study was to evaluate the biological effects of opium on the number of peripheral blood cells and red blood cells (RBCs) indices in diabetic rats. Peripheral blood samples were collected from diabetic, opium-addicted, diabetic opium-addicted and normal male and female rats and hematological parameters were measured. The mean number of white blood cells (WBCs) was significantly higher in diabetic opium-addict females compared to diabetic non-addict female group. In both male and female, the mean number of neutrophils was significantly higher and the mean number of lymphocytes was lower in diabetic opium-addicted rats than those observed in diabetic non-addicted group. In diabetic opium-addicted male group the mean counts of RBC significantly increased as compared with diabetic male group. However, in diabetic addicted female, the mean number of RBCs was significantly lower than diabetic non-addicted female group. In both males and females, the mean number of platelets was significantly lower in diabetic addict rats compared to diabetic non-addict group. Generally, the results indicated that opium addiction has different effects on male and female rats according to the number of WBC, RBC and RBC indices. It could also be concluded that in the opium-addicts the risk of infection is enhanced due to the weakness of immune system as a result of the imbalance effect of opium on the immune cells.

  14. Nanotechnology applications in hematological malignancies (Review)

    SAMIR, AHMED; ELGAMAL, BASMA M; GABR, HALA; SABAAWY, HATEM E

    2015-01-01

    A major limitation to current cancer therapies is the development of therapy-related side-effects and dose limiting complications. Moreover, a better understanding of the biology of cancer cells and the mechanisms of resistance to therapy is rapidly developing. The translation of advanced knowledge and discoveries achieved at the molecular level must be supported by advanced diagnostic, therapeutic and delivery technologies to translate these discoveries into useful tools that are essential in achieving progress in the war against cancer. Nanotechnology can play an essential role in this aspect providing a transforming technology that can translate the basic and clinical findings into novel diagnostic, therapeutic and preventive tools useful in different types of cancer. Hematological malignancies represent a specific class of cancer, which attracts special attention in the applications of nanotechnology for cancer diagnosis and treatment. The aim of the present review is to elucidate the emerging applications of nanotechnology in cancer management and describe the potentials of nanotechnology in changing the key fundamental aspects of hematological malignancy diagnosis, treatment and follow-up. PMID:26134389

  15. Hematological complications in children subjected to extracorporeal membrane oxygenation.

    Santiago, M J; Gómez, C; Magaña, I; Muñoz, V; Saiz, P; Sánchez, A; López-Herce, J

    2018-03-29

    To analyze the hematological complications and need for transfusions in children receiving extracorporeal life support (ECLS). A retrospective study was carried out. A pediatric intensive care unit. Children under 18 years of age treated with ECLS between September 2006 and November 2015. None. Patient and ECLS characteristics, anticoagulation, hematological and coagulation parameters, transfusions and clinical course. A total of 100 patients (94 with heart disease) with a median age of 11 months were studied. Seventy-six patients presented bleeding. The most frequent bleeding point being the mediastinum and 39 patients required revision surgery. In the first 3days, 97% of the patients required blood transfusion (34.4ml/kg per day), 94% platelets (21.1ml/kg per day) and 90% plasma (26.6ml/kg per day). Patients who were in the postoperative period, those who were bleeding at the start of ECLS, those requiring revision surgery, those who could not suspend extracorporeal circulation, and those subjected to transthoracic cannulation required a greater volume of transfusions than the rest of the patients. Thromboembolism occurred in 14 patients and hemolysis in 33 patients. Mortality among the children who were bleeding at the start of ECLS (57.6%) was significantly higher than in the rest of the patients (37.5%) (P=0.048). Children treated with ECLS present high blood product needs. The main factors related to transfusions were postoperative period, bleeding at the start of ECLS, revision surgery, transthoracic cannulation, and the impossibility of suspending extracorporeal circulation. Children with bleeding suffered greater mortality than the rest of the patients. Copyright © 2018 Elsevier España, S.L.U. y SEMICYUC. All rights reserved.

  16. Invasive fungal diseases in children with hematologic disorders

    Ünsal Günay

    2009-12-01

    Full Text Available Objective: Fungal infection is a significant problem, causing of infective deaths of leukemic patients. The situation in developing countries is not well documented. The purpose of this study was characterizing IFD by analyzing data retrospectively to determine the incidence, predisposing factors, diagnostic methods, efficacy of treatment, and the outcome in pediatric patients with hematological disorders. Materials and Methods: There were 160 children with leukemia (22 AML, 129 ALL and 9 with aplastic anemia (AA. The diagnostic criteria for IFD were defined according to the EORTC/MSG, 2008. IFD was classified as proven or probable. Empiric antifungal treatment with L-AmB was commenced by day 5-7 of persistent fever. Patients with invasive aspergillosis (IA who were refractory to primary treatment were commenced on voriconazole (VCZ. Salvage therapy as combination of VCZ and caspofungin was given to those with progressive infection. Results: The incidence of IFD was found 23 (14.3%. 19 with leukemia (14 ALL, 5 AML and 4 with aplastic anemia were diagnosed as IFD. IA was the dominant cause of infection (n=17 and the rest (n: 6 had candidiasis. Ten children had “proven” infection and 13 children were defined as “probable”. The most frequent site of infection was lungs. In our series, the most frequently used diagnostic methods were clinical findings (100% and radiologic methods (84%. The success rate of treatment for candidiasis and IA were found 60%, 71% respectively. IFD related death rate was found 30%.Conclusion: IFD is still a major morbidity and mortality reason in children with hematologic disorders. However, the availability of new antifungal treatments and diagnostic tests will improve the survival rates in these children.

  17. A Review on hematology and hemoglobin of fish

    Ebru YILMAZ

    2015-01-01

    Full Text Available Determination of hematological parameters of fish living in natüre helps to recognize population and to determinate of pollutants in the aquatic environment. In this review, hematological parameters of fish, fish hemoglobin and the Bohr effect were given information.

  18. The Effects of Altitude Training on Erythropoietic Response and Hematological Variables in Adult Athletes: A Narrative Review

    Płoszczyca, Kamila; Langfort, Józef; Czuba, Miłosz

    2018-01-01

    Background: One of the goals of altitude training is to increase blood oxygen-carrying capacity in order to improve sea-level endurance performance in athletes. The elevated erythropoietin (EPO) production in hypoxia is a key factor in the achievement of enhanced hematological variables. The level of the EPO increase and acceleration of erythropoiesis depend on the duration of exposure and degree of hypoxia. Furthermore, many other factors may affect the hematological response to altitude training. Aim: The purpose of this narrative review was to: (1) analyze the kinetics of EPO and hematological variables during and after altitude training; (2) summarize the current state of knowledge about the possible causes of individual or cohort differences in EPO and hematological response to altitude training; (3) formulate practical guidelines for athletes to improve the efficiency of altitude training. Methods: A narrative review was performed following an electronic search of the databases PubMed/MEDLINE and SPORTDiscus via EBSCO for all English-language articles published between 1997 and 2017. Results: Complete unification of results from studies on EPO kinetics was difficult due to different time and frequency of blood sampling by different researchers during and after altitude training, but the data presented in the reviewed literature allowed us to detect certain trends. The results of the reviewed studies were divergent and indicated either increase or no change of hematological variables following altitude training. Factors that may affect the hematological response to altitude training include hypoxic dose, training content, training background of athletes, and/or individual variability of EPO production. Conclusions: Despite the potential benefits arising from altitude training, its effectiveness in improving hematological variables is still debatable. Further research and better understanding of factors influencing the response to altitude, as well as factors

  19. The Effects of Altitude Training on Erythropoietic Response and Hematological Variables in Adult Athletes: A Narrative Review.

    Płoszczyca, Kamila; Langfort, Józef; Czuba, Miłosz

    2018-01-01

    Background: One of the goals of altitude training is to increase blood oxygen-carrying capacity in order to improve sea-level endurance performance in athletes. The elevated erythropoietin (EPO) production in hypoxia is a key factor in the achievement of enhanced hematological variables. The level of the EPO increase and acceleration of erythropoiesis depend on the duration of exposure and degree of hypoxia. Furthermore, many other factors may affect the hematological response to altitude training. Aim: The purpose of this narrative review was to: (1) analyze the kinetics of EPO and hematological variables during and after altitude training; (2) summarize the current state of knowledge about the possible causes of individual or cohort differences in EPO and hematological response to altitude training; (3) formulate practical guidelines for athletes to improve the efficiency of altitude training. Methods: A narrative review was performed following an electronic search of the databases PubMed/MEDLINE and SPORTDiscus via EBSCO for all English-language articles published between 1997 and 2017. Results: Complete unification of results from studies on EPO kinetics was difficult due to different time and frequency of blood sampling by different researchers during and after altitude training, but the data presented in the reviewed literature allowed us to detect certain trends. The results of the reviewed studies were divergent and indicated either increase or no change of hematological variables following altitude training. Factors that may affect the hematological response to altitude training include hypoxic dose, training content, training background of athletes, and/or individual variability of EPO production. Conclusions: Despite the potential benefits arising from altitude training, its effectiveness in improving hematological variables is still debatable. Further research and better understanding of factors influencing the response to altitude, as well as factors

  20. The Effects of Altitude Training on Erythropoietic Response and Hematological Variables in Adult Athletes: A Narrative Review

    Kamila Płoszczyca

    2018-04-01

    Full Text Available Background: One of the goals of altitude training is to increase blood oxygen-carrying capacity in order to improve sea-level endurance performance in athletes. The elevated erythropoietin (EPO production in hypoxia is a key factor in the achievement of enhanced hematological variables. The level of the EPO increase and acceleration of erythropoiesis depend on the duration of exposure and degree of hypoxia. Furthermore, many other factors may affect the hematological response to altitude training.Aim: The purpose of this narrative review was to: (1 analyze the kinetics of EPO and hematological variables during and after altitude training; (2 summarize the current state of knowledge about the possible causes of individual or cohort differences in EPO and hematological response to altitude training; (3 formulate practical guidelines for athletes to improve the efficiency of altitude training.Methods: A narrative review was performed following an electronic search of the databases PubMed/MEDLINE and SPORTDiscus via EBSCO for all English-language articles published between 1997 and 2017.Results: Complete unification of results from studies on EPO kinetics was difficult due to different time and frequency of blood sampling by different researchers during and after altitude training, but the data presented in the reviewed literature allowed us to detect certain trends. The results of the reviewed studies were divergent and indicated either increase or no change of hematological variables following altitude training. Factors that may affect the hematological response to altitude training include hypoxic dose, training content, training background of athletes, and/or individual variability of EPO production.Conclusions: Despite the potential benefits arising from altitude training, its effectiveness in improving hematological variables is still debatable. Further research and better understanding of factors influencing the response to altitude, as well

  1. Hematological profile of sickle cell disease from South Gujarat, India

    Sanjeev Shyam Rao

    2012-05-01

    Full Text Available The aim of this study was to determine hematological profile of sickle cell disease (SCD from Surat, South Gujarat, India. This prospective cross-sectional study was conducted in the Department of Pediatrics and Sickle Cell Anemia Laboratory, Faculty of Pathology, Government Medical College, Surat, India, between July 2009 and December 2010. Patients included in this study were in their steady state for a long period of time without any symptoms related to SCD or other diseases which could affect the hematological parameters. Venous blood of all patients was collected in ethylenediaminetetraacetic acid and hematological indices were measured. Thirty-three subjects homozygous in all were studied for their hematological parameters for sickle cell anemia. Moderate to severe anemia, low mean cell volume and high foetal hemoglobin dominate the hematological profile of SCD children.

  2. Hematology laboratory standardization: a plan for harmonization in Asia.

    Bunyaratvej, A; Tatsumi, N; Funahara, Y

    1999-01-01

    Hematology laboratory is generally required in the hospital. At the macroscale, hematology laboratories have served a large number of population. In Asia, more than 3,000 million people are potentially to use the hematology laboratory service, particularly the complete blood count. Since 1970s, automated technology has been introduced to Asia and as years passed by, technology diversity is increasing. However, there are considerable number of hematology laboratories that have no automated machine. They are still relied on manual technology which is still variable in spectrophotometer for hemoglobin determination, centrifuge for hematocrit and diluting pipet for cell counting. In particular, blood smear preparation and interpretation are very difficult to control for standardization from person to person and laboratory to laboratory. Different methodology and a large population in the huge geographical area in Asia, the agreement of standard criteria is greatly important. This report has shown strategy and action plan to reach the goal of hematology laboratory standardization in Asia.

  3. Expanding role of lenalidomide in hematologic malignancies

    Ghosh, Nilanjan; Grunwald, Michael R; Fasan, Omotayo; Bhutani, Manisha

    2015-01-01

    Lenalidomide is an immunomodulatory agent that has been approved by the US Food and Drug Administration for treatment of multiple myeloma, deletion 5q myelodysplastic syndrome, and mantle cell lymphoma. In addition, it has clinical activity in lymphoproliferative disorders and acute myeloid leukemia. The mode of action includes immunomodulatory, anti-inflammatory, antiangiogenic, and antiproliferative mechanisms. The antitumor effect is a result of direct interference of key pathways in tumor cells and indirect modulation of the tumor microenvironment. There has been no recent collective review on lenalidomide in multiple myeloma, myelodysplastic syndrome/acute myeloid leukemia, and lymphoma. This review summarizes the results of current clinical studies of lenalidomide, alone and in combination with other agents, as a therapeutic option for various hematologic malignancies

  4. Vorinostat in solid and hematologic malignancies

    Richon Victoria M

    2009-07-01

    Full Text Available Abstract Vorinostat (Zolinza®, a histone deacetylase inhibitor, was approved by the US Food and Drug Administration in October 2006 for the treatment of cutaneous manifestations in patients with cutaneous T-cell lymphoma who have progressive, persistent or recurrent disease on or following two systemic therapies. This review summarizes evidence on the use of vorinostat in solid and hematologic malignancies and collated tolerability data from the vorinostat clinical trial program. Pooled vorinostat clinical trial data from 498 patients with solid or hematologic malignancies show that vorinostat was well tolerated as monotherapy or combination therapy. The most commonly reported drug-related adverse events (AEs associated with monotherapy (n = 341 were fatigue (61.9%, nausea (55.7%, diarrhea (49.3%, anorexia (48.1%, and vomiting (32.8%, and Grade 3/4 drug-related AEs included fatigue (12.0%, thrombocytopenia (10.6%, dehydration (7.3%, and decreased platelet count (5.3%. The most common drug-related AEs observed with vorinostat in combination therapy (n = 157, most of whom received vorinostat 400 mg qd for 14 days were nausea (48.4%, diarrhea (40.8%, fatigue (34.4%, vomiting (31.2%, and anorexia (20.4%, with the majority of AEs being Grade 2 or less. In Phase I trials, combinations with vorinostat were generally well tolerated and preliminary evidence of anticancer activity as monotherapy or in combination with other systemic therapies has been observed across a range of malignancies. Ongoing and planned studies will further evaluate the potential of vorinostat in combination therapy, including combinations with radiation, in patients with diverse malignancy types, including non-small-cell lung cancer, glioblastoma multiforme, multiple myeloma, and myelodysplastic syndrome.

  5. Hematological profile variation in the european bison (Bison bonasus l., 1758 as a function of age, sex and health condition

    Razvan Deju

    2011-12-01

    Full Text Available The paper analyzes some new hematological data on the European bison from the Natural Park of Vanatori Neamt, a comparison being made both between the values recorded in animals of different ages (2-8 years and sexes, and between the values of the European bison and those registered in some kindred ruminant mammals, such as the deer and the cow. More than that, a comparison is made between the data taken over from healthy bisons and from an animal affected by severe anemia and multiple parasitary indices. Hematological prosperity increases with the age in female bisons, while a decrease is reported in males, especially in the case of suffering animals, versus the healthy ones. Comparatively with other big mammals, the hematological profile of the bison is much more similar to that of domestic ruminants, being wholly different from that of the wild deer.

  6. Biological variation of platelet parameters determined by the Sysmex XN hematology analyzer.

    Buoro, Sabrina; Seghezzi, Michela; Manenti, Barbara; Pacioni, Aurelio; Carobene, Anna; Ceriotti, Ferruccio; Ottomano, Cosimo; Lippi, Giuseppe

    2017-07-01

    This study was aimed to define the short- and medium-term biological variation (BV) estimates, the index of individuality and the reference change value (RCV) of platelet count, platelet distribution width, mean platelet volume, platelet larger cell ratio, plateletcrit and immature platelet fraction. The study population consisted of 43 health subjects, who participated to the assessment of medium-term (21 subjects; blood sampling once a week for 5 consecutive weeks) and short-term (22 subjects; blood sampling once a day for 5 consecutive days) BV study, using Sysmex XN-module. Eight subjects were also scheduled to participate to both phases. The data were subject to outlier analysis prior to CV-ANOVA, to determine the BV estimates with the relative confidence intervals. The medium-term and short-term within-subject BV (CV I ) was comprised between 2.3 and 7.0% and 1.1-8.6%, whereas the medium-term and short-term between-subjects BV (CV G ) was comprised between 7.1 and 20.7% and 6.8-48.6%. The index of individuality and index of heterogeneity were always respectively 0.63 for all the parameters, in both arms of the study. The RCVs were similar for all parameters, in both arms of the study. This study allowed to define the BV estimates of many platelet parameters, some of them unavailable in literature. The kinetics of platelet turnover suggests the use of short-term BV data for calculating analytical goals and RCV. The correct clinical interpretation of platelet parameters also necessitates that each laboratory estimates local RCV values. Copyright © 2017 Elsevier B.V. All rights reserved.

  7. A risk prediction score for invasive mold disease in patients with hematological malignancies.

    Marta Stanzani

    Full Text Available BACKGROUND: A risk score for invasive mold disease (IMD in patients with hematological malignancies could facilitate patient screening and improve the targeted use of antifungal prophylaxis. METHODS: We retrospectively analyzed 1,709 hospital admissions of 840 patients with hematological malignancies (2005-2008 to collect data on 17 epidemiological and treatment-related risk factors for IMD. Multivariate regression was used to develop a weighted risk score based on independent risk factors associated with proven or probable IMD, which was prospectively validated during 1,746 hospital admissions of 855 patients from 2009-2012. RESULTS: Of the 17 candidate variables analyzed, 11 correlated with IMD by univariate analysis, but only 4 risk factors (neutropenia, lymphocytopenia or lymphocyte dysfunction in allogeneic hematopoietic stem cell transplant recipients, malignancy status, and prior IMD were retained in the final multivariate model, resulting in a weighted risk score 0-13. A risk score of 5% of IMD, with a negative predictive value (NPV of 0.99, (95% CI 0.98-0.99. During 2009-2012, patients with a calculated risk score at admission of 6 (0.9% vs. 10.6%, P <0.001. CONCLUSION: An objective, weighted risk score for IMD can accurately discriminate patients with hematological malignancies at low risk for developing mold disease, and could possibly facilitate "screening-out" of low risk patients less likely to benefit from intensive diagnostic monitoring or mold-directed antifungal prophylaxis.

  8. Weights, hematology and serum chemistry of seven species of free-ranging tropical pelagic seabirds

    Work, Thierry M.

    1996-01-01

    I established reference values for weight, hematology, and serum chemistry for seven species of free-ranging Hawaiian tropical pelagic seabirds comprising three orders (Procellariiformes, Pelecaniformes, Charadriiformes) and six families (Procellariidae, Phaethontidae, Diomedeidae, Sulidae, Fregatidae, and Laridae). Species examined included 84 Hawaiian dark-rumped petrels (Pterodoma phaeopygia), 90 wedge-tailed shearwaters (Puffinus pacificus), 151 Laysan albatrosses (Diomedea immutabilis), 69 red-footed boobies (Sula sula), 154 red-tailed tropicbirds (Phaeton rubricauda), 90 great frigatebirds (Fregata minor), and 72 sooty terns (Sterna fuscata). Hematocrit, total plasma solids, total and differential white cell counts, serum glucose, calcium, phosphorus, uric acid, total protein, albumin, globulin, aspartate aminotransferase and creatinine phosphokinase were analyzed. Among and within species, hematology and chemistry values varied with age, sex, season, and island of collection. Despite this variation, order-wide trends were observed.

  9. Analysis and optimization of hybrid excitation permanent magnet synchronous generator for stand-alone power system

    Wang, Huijun; Qu, Zheng; Tang, Shaofei; Pang, Mingqi; Zhang, Mingju

    2017-08-01

    In this paper, electromagnetic design and permanent magnet shape optimization for permanent magnet synchronous generator with hybrid excitation are investigated. Based on generator structure and principle, design outline is presented for obtaining high efficiency and low voltage fluctuation. In order to realize rapid design, equivalent magnetic circuits for permanent magnet and iron poles are developed. At the same time, finite element analysis is employed. Furthermore, by means of design of experiment (DOE) method, permanent magnet is optimized to reduce voltage waveform distortion. Finally, the validity of proposed design methods is validated by the analytical and experimental results.

  10. environmental/climatic effect on stand-alone solar energy supply

    This paper investigates the climatic effects and environmental variations on the perfor- mance of a ... inter-connected arrays due to shades from clouds, tress and ... Modeling of Solar Module .... needs. The earth revolves around the sun in an.

  11. Letting Go of Stand-Alone Technology: How to Blend Technology into Literacy Stations

    Calvert, Heather

    2015-01-01

    With the nationwide focus on increasing students understanding and use of technology, many teachers are beginning to incorporate a variety of technology into small group rotations. However, the use of technology during these rotations often does not require students to use higher level thinking or problem solving skills. By eliminating the…

  12. Sizing and economic analysis of stand alone photovoltaic system with hydrogen storage

    Nordin, N. D.; Rahman, H. A.

    2017-11-01

    This paper proposes a design steps in sizing of standalone photovoltaic system with hydrogen storage using intuitive method. The main advantage of this method is it uses a direct mathematical approach to find system’s size based on daily load consumption and average irradiation data. The keys of system design are to satisfy a pre-determined load requirement and maintain hydrogen storage’s state of charge during low solar irradiation period. To test the effectiveness of the proposed method, a case study is conducted using Kuala Lumpur’s generated meteorological data and rural area’s typical daily load profile of 2.215 kWh. In addition, an economic analysis is performed to appraise the proposed system feasibility. The finding shows that the levelized cost of energy for proposed system is RM 1.98 kWh. However, based on sizing results obtained using a published method with AGM battery as back-up supply, the system cost is lower and more economically viable. The feasibility of PV system with hydrogen storage can be improved if the efficiency of hydrogen storage technologies significantly increases in the future. Hence, a sensitivity analysis is performed to verify the effect of electrolyzer and fuel cell efficiencies towards levelized cost of energy. Efficiencies of electrolyzer and fuel cell available in current market are validated using laboratory’s experimental data. This finding is needed to envisage the applicability of photovoltaic system with hydrogen storage as a future power supply source in Malaysia.

  13. Optimal Sizing and Operation of Stand-Alone Hybrid Power Systems

    Kyriakidis, Ioannis; Chaudhary, Sanjay; Pillai, Jayakrishnan Radhakrishna

    2014-01-01

    for autonomous applications. Based on the island’s wind and solar potential, wind and solar systems appear as the most competitive solution while battery technologies provide the most feasible option for storing the excess energy. In the next, simulation models are developed in HOMER software. Various ratings...... of Renewable Energy Sources and Energy Storage Systems are considered and the most feasible combinations with respect to the Net Present Cost are calculated. The results have been assessed according to three scenarios, each of them representing a different policy and encountering several constraints....... Afterwards, steady-state analysis of the network is carried out considering typical cases of seasonal demand. The static model is developed in DIgSILENT PowerFactory software and the system’s behavior is investigated. In the following, the optimal placement for the wind, solar and storage units is discussed...

  14. Assessing Self-Regulation of Learning Dimensions in a Stand-alone MOOC Platform

    Daniel Friday Owoichoche Onah

    2017-06-01

    Full Text Available A capacity for self-regulated learning (SRL has long been recognised as an important factor in successful studies. Although educational researchers have started to investigate the concept of SRL in the context of online education, very little is yet known about SRL in relation to massive open online courses (MOOCs or of appropriate strategies to foster SRL skills in MOOC learners. Self-regulation is particularly important in a MOOC-based study, which demands effective independent learning, and where widely acknowledged high dropout rates are observed. This study reports an investigation and assessment of the concept of SRL using a novel MOOC platform (eLDa by providing study options (either via a self-directed learning or instructor-led learning using a novel learning tool. In view of this, the research presents general description of self-regulated learning and explored the various existing dimensions used to expose the learners SRL skills. Drawing comparison of the online tool, the results and findings of the data were analysed. The study dis¬cusses how the various dimensions contributed to the knowledge representation of the self-regulated learning abilities shown by the learners. We present how these SRL dimensions captured using the measuring instrument contributes to our growing understanding of the distinctive features of the individual learner’s self-regulated learning. MOOCs success required a high performance of self-regulated learning abilities which at the moment very little has shown these degree of supporting SRL skills. This paper presents preliminary evaluation of a novel e-learning tool known, as ‘eLDa’ developed to implement this investi¬gation of self-regulation of learning. The research applied a modified online self-regulated learning questionnaire (OSLQ as the instrument to measure the SRL skills. The modified questionnaire known as MOOC OSLQ (MOSLQ was developed with a 19-item scale questions that exposes the six SRL dimensions used in this study.

  15. Perancangan Photovoltaic Stand Alone Sebagai Catu Daya Pada Base Transceiver Station Telekomunikasi Di Pulau Nusa Penida

    I P Eka Indrawan

    2013-06-01

    Full Text Available Salah satu perangkat dalam jaringan komunikasi seluler adalah BTS (Base Transceiver Station. BTS yang ada di pulau Nusa Penida adalah BTS Nusa Penida dengan alamat desa kutampi dengan luas 500 m2. Sistem kelistrikan BTS  Nusa Penida dipasok oleh PLN dan genset,  dimana pada saat terjadi pemadaman energi listrik pada umumnya mempergunakan genset sebagai sumber energi listrik. Penggunaan genset mengakibatkan biaya operasional sangat tinggi, untuk itu diperlukan sumber lain yang lebih efisien. Besarnya potensi insolasi sinar harian matahari di Nusa penida, bisa sebagai  alternatif lain untuk sumber energi listrik dimana energi matahari bisa sebagai energi terbarukan untuk catu daya tambahan di BTS Nusa Penida yang pada akhirnya dapat menjaga  kestabilan suplai energi listrik ke BTS dan akses masyarakat terhadap informasi melalui seluler menjadi tidak terganggu. PV (Photovoltaic merupakan salah satu energi terbarukan yang dapat digunakan sebagai energi terbarukan untuk catu daya tambahan di BTS. Sistem PV yang dikembangkan untuk mensuplai energi listrik di BTS direncanakan sebesar 25%, adalah sistem PV yang hybrid dengan suplai listrik PLN. Besar daya PV yang dibangkitkan untuk mensuplai energi listrik di BTS adalah 9 kWp, yang dihasilkan dari panel PV sebanyak 45 panel dengan kapasitas panel PV adalah 200Wp dan kapasitas baterai yang akan digunakan adalah 3.800 Ah dengan total baterai 16. Analisis kelayakan investasi PV tanpa baterai dan PV dengan baterai yang dilakukan dengan menggunakan NPV, PI dan DPP menunjukkan hasil bahwa investasi PV layak untuk dilaksanakan. Untuk nilai NPV dan PI didapatkan kedua hasil investasi (> 0. Sedangkan untuk DPP didapatkan kedua hasil investasi dihasilkan lebih kecil dari periode umur proyek yang sudah ditetapkan, yaitu selama 25 tahun.

  16. Transforming stand-alone expert system into a community of cooperating agents

    Jennings, N R; Aarnts, R P; Fuchs, J; Skarek, Paul

    1993-01-01

    Distributed Artificial Intelligence (DAI) systems in which multiple problem solving agents cooperate to achieve a common objective is a rapidly emerging and promising technology. However, as yet, there have been relatively few reported cases of such systems being employed to tackle real-world problems in realistic domains. One of the reasons for this is that DAI researchers have given virtually no consideration to the process of incorporating pre-existing systems into a community of cooperating agents. Yet reuse is a primary consideration for any organisation with a large software base. To redress the balance, this paper reports on an experiment undertaken at the CERN laboratories, in which two pre-existing and standalone expert systems for diagnosing faults in a particle accelerator were transformed into a community of cooperating agents. The experiences and insights gained during this process provide a valuable first step towards satisfying the needs of potential users of DAI technology - identifying the ty...

  17. New Scheme for Seamless Operation for Stand-Alone Power Systems

    Hyun-Jun Kim

    2016-06-01

    Full Text Available On remote islands photovoltaic (PV panels with battery energy storage systems (BESSs supply electric power to customers in parallel operation with engine generators (EGs to reduce fuel consumption and environmental burden. A BESS operates in voltage control mode when it supplies power to loads alone, while it operates in current control mode when it supplies power to loads in parallel with the EG. This paper proposes a smooth mode change of the BESS from current control to voltage control by using initial value at the output of integral part in the voltage controller, and a smooth mode change from voltage control to current control by tracking the EG output voltage to the BESS output voltage using a phase-locked loop (PLL. The feasibility of the proposed scheme was verified through computer simulations and experiments with a scaled prototype.

  18. Feedforward control strategy for the state-decoupling Stand-alone UPS with LC output filter

    Lu, Jinghang; Savaghebi, Mehdi; Guerrero, Josep M.

    2017-01-01

    . In order to further increase the load current disturbance rejection capability of the state-decoupling in UPS system, a feedforward control strategy is proposed. In addition, the design principle for the current and voltage regulators are discussed. Simulation and experimental results are provided......In this paper, the disturbance rejection performance of the cascaded control strategy for UPS system is investigated. The comparison of closed loop system performance between conventional cascaded control (CCC) strategy and state-decoupling cascaded control (SDCC) strategy are further explored...

  19. APT - NASA ENHANCED VERSION OF AUTOMATICALLY PROGRAMMED TOOL SOFTWARE - STAND-ALONE VERSION

    Premo, D. A.

    1994-01-01

    The APT code is one of the most widely used software tools for complex numerically controlled (N/C) machining. APT is an acronym for Automatically Programmed Tools and is used to denote both a language and the computer software that processes that language. Development of the APT language and software system was begun over twenty years ago as a U. S. government sponsored industry and university research effort. APT is a "problem oriented" language that was developed for the explicit purpose of aiding the N/C machine tools. Machine-tool instructions and geometry definitions are written in the APT language to constitute a "part program." The APT part program is processed by the APT software to produce a cutter location (CL) file. This CL file may then be processed by user supplied post processors to convert the CL data into a form suitable for a particular N/C machine tool. This June, 1989 offering of the APT system represents an adaptation, with enhancements, of the public domain version of APT IV/SSX8 to the DEC VAX-11/780 for use by the Engineering Services Division of the NASA Goddard Space Flight Center. Enhancements include the super pocket feature which allows concave and convex polygon shapes of up to 40 points including shapes that overlap, that leave islands of material within the pocket, and that have one or more arcs as part of the pocket boundary. Recent modifications to APT include a rework of the POCKET subroutine and correction of an error that prevented the use within a macro of a macro variable cutter move statement combined with macro variable double check surfaces. Former modifications included the expansion of array and buffer sizes to accommodate larger part programs, and the insertion of a few user friendly error messages. The APT system software on the DEC VAX-11/780 is organized into two separate programs: the load complex and the APT processor. The load complex handles the table initiation phase and is usually only run when changes to the APT processor capabilities are made. This phase initializes character recognition and syntax tables for the APT processor by creating FORTRAN block data programs. The APT processor consists of four components: the translator, the execution complex, the subroutine library, and the CL editor. The translator examines each APT statement in the part program for recognizable structure and generates a new statement, or series of statements, in an intermediate language. The execution complex processes all of the definition, motion, and related statements to generate cutter location coordinates. The subroutine library contains routines defining the algorithms required to process the sequenced list of intermediate language commands generated by the translator. The CL editor re-processes the cutter location coordinates according to user supplied commands to generate a final CL file. A sample post processor is also included which translates a CL file into a form for use with a Wales Strippit Fabramatic Model 30/30 sheet metal punch. The user should be able to readily develop post processors for other N/C machine tools. The APT language is a statement oriented, sequence dependent language. With the exception of such programming techniques as looping and macros, statements in an APT program are executed in a strict first-to-last sequence. In order to provide programming capability for the broadest possible range of parts and of machine tools, APT input (and output) is generalized, as represented by 3-dimensional geometry and tools, and arbitrarily uniform, as represented by the moving tool concept and output data in absolute coordinates. A command procedure allows the user to select the desired part program, ask for a graphics file of cutter motions in IGES format, and submit the procedure as a batch job, if desired. The APT system software is written in FORTRAN 77 for batch and interactive execution and has been implemented on a DEC VAX series computer under VMS 4.4. The enhancements for this version of APT were last updated in June, 1989. The NASA adaptation, with enhancements, of the public domain version of the APT IV/SSX8 software to the DEC VAX-11/780 is available by license for a period of ten (10) years to approved licensees. The licensed program product delivered includes the APT IV/SSX8 system source code, object code, executable images, and command procedures and one set of supporting documentation. Additional copies of the supporting documentation may be purchased at any time at the price indicated below.

  20. A high-performance stand-alone solar PV power system for LED lighting

    Huang, B. J.

    2010-06-01

    The present study developed a high-performance solar PV power technology for the LED lighting of a solar home system. The nMPPO (near-Maximum-Power- Point- Operation) design is employed in system design to eliminate MPPT. A feedback control system using pulse width modulation (PWM) technique was developed for battery charging control which can increase the charging capacity by 78%. For high-efficiency lighting, the LED is directly driven by battery using a PWM discharge control to eliminate a DC/DC converter. Two solar-powered LED lighting systems (50W and 100W LED) were built. The long-term outdoor tests have shown that the loss of load probability for full-night lighting requirement is zero for 50W LED and 3.6% for 100W LED. © 2010 IEEE.

  1. A high-performance stand-alone solar PV power system for LED lighting

    Huang, B. J.; Hsu, P. C.; Wu, M. S.; Chen, K.Y.

    2010-01-01

    The present study developed a high-performance solar PV power technology for the LED lighting of a solar home system. The nMPPO (near-Maximum-Power- Point- Operation) design is employed in system design to eliminate MPPT. A feedback control system

  2. Last Stand-alone Beam Test of the Hadronic End-cap Calorimeter (HEC) Finished.

    Oberlack, H

    One quarter of all 134 HEC modules are tested with electron, pion and muon beams: two "partial HEC wheels", three HEC1 modules and three HEC2 modules, are used in a standard setup using the HEC cryostat in the H6 beam line. The picture shows a view of the set-up in the cryostat during the installation. MC results show that in this setup the energy leakage is well under control - well below 5 %. In addition, the other three quarters of modules are tested in technical cold tests. Using calibration signals, a detailed test of the cabling, cold electronics, crosstalk and noise performance is being done. The beam tests started with four prototype modules per run in '97, when technological optimization was still the key issue. From '98 onwards, modules of the "module 0" type have been tested, typically in two run periods per year. Finally in '99 the series production has started, with first beam test of series modules in 2000. Since then 57 series modules have been cold tested, 24 of them actually in beam tests. T...

  3. Wind-driven stand-alone DFIG with battery and pumped hydro ...

    Renewable energy electric conversion system; induction generators; wind power generation; energy storage; power converters. ... converter, (ii) wide speed operation of wind-driven DFIG, (iii) reduced battery capacity, (iv) high energy storage using PHSP and (v) availability of continuous power to the isolated loads.

  4. Stand-alone Cosmic Muon Reconstruction Before Installation of the CMS Silicon Strip Tracker

    Adam, W.; Dragicevic, M.; Friedl, M.; Fruhwirth, R.; Hansel, S.; Hrubec, J.; Krammer, M.; Oberegger, M.; Pernicka, M.; Schmid, S.; Stark, R.; Steininger, H.; Uhl, D.; Waltenberger, W.; Widl, E.; Van Mechelen, P.; Cardaci, M.; Beaumont, W.; de Langhe, E.; de Wolf, E.A.; Delmeire, E.; Hashemi, M.; Bouhali, O.; Charaf, O.; Clerbaux, B.; Dewulf, J.-P.; Elgammal, S.; Hammad, G.; de Lentdecker, G.; Marage, P.; Vander Velde, C.; Vanlaer, P.; Wickens, J.; Adler, V.; Devroede, O.; De Weirdt, S.; D'Hondt, J.; Goorens, R.; Heyninck, J.; Maes, J.; Mozer, Matthias Ulrich; Tavernier, S.; Van Lancker, L.; Van Mulders, P.; Villella, I.; Wastiels, C.; Bonnet, J.-L.; Bruno, G.; De Callatay, B.; Florins, B.; Giammanco, A.; Gregoire, G.; Keutgen, Th.; Kcira, D.; Lemaitre, V.; Michotte, D.; Militaru, O.; Piotrzkowski, K.; Quertermont, L.; Roberfroid, V.; Rouby, X.; Teyssier, D.; Daubie, E.; Anttila, E.; Czellar, S.; Engstrom, P.; Harkonen, J.; Karimaki, V.; Kostesmaa, J.; Kuronen, A.; Lampen, T.; Linden, T.; Luukka, P.-R.; Maenpaa, T.; Michal, S.; Tuominen, E.; Tuominiemi, J.; Ageron, M.; Baulieu, G.; Bonnevaux, A.; Boudoul, G.; Chabanat, E.; Chabert, E.; Chierici, R.; Contardo, D.; Della Negra, R.; Dupasquier, T.; Gelin, G.; Giraud, N.; Guillot, G.; Estre, N.; Haroutunian, R.; Lumb, N.; Perries, S.; Schirra, F.; Trocme, B.; Vanzetto, S.; Agram, J.-L.; Blaes, R.; Drouhin, F.; Ernenwein, J.-P.; Fontaine, J.-C.; Berst, J.-D.; Brom, J.-M.; Didierjean, F.; Goerlach, U.; Graehling, P.; Gross, L.; Hosselet, J.; Juillot, P.; Lounis, A.; Maazouzi, C.; Olivetto, C.; Strub, R.; Van Hove, P.; Anagnostou, G.; Brauer, R.; Esser, H.; Feld, L.; Karpinski, W.; Klein, K.; Kukulies, C.; Olzem, J.; Ostapchuk, A.; Pandoulas, D.; Pierschel, G.; Raupach, F.; Schael, S.; Schwering, G.; Sprenger, D.; Thomas, M.; Weber, M.; Wittmer, B.; Wlochal, M.; Beissel, F.; Bock, E.; Flugge, G.; Gillissen, C.; Hermanns, T.; Heydhausen, D.; Jahn, D.; Kaussen, G.; Linn, A.; Perchalla, L.; Poettgens, M.; Pooth, O.; Stahl, A.; Zoeller, M.H.; Buhmann, P.; Butz, E.; Flucke, G.; Hamdorf, R.; Hauk, J.; Klanner, R.; Pein, U.; Schleper, P.; Steinbruck, G.; Blum, P.; De Boer, W.; Dierlamm, A.; Dirkes, G.; Fahrer, M.; Frey, M.; Furgeri, A.; Hartmann, F.; Heier, S.; Hoffmann, K.-H.; Kaminski, J.; Ledermann, B.; Liamsuwan, T.; Muller, S.; Muller, Th.; Schilling, F.-P.; Simonis, H.-J.; Steck, P.; Zhukov, V.; Cariola, P.; De Robertis, G.; Ferorelli, R.; Fiore, L.; Preda, M.; Sala, G.; Silvestris, L.; Tempesta, P.; Zito, G.; Creanza, D.; De Filippis, N.; De Palma, M.; Giordano, D.; Maggi, G.; Manna, N.; My, S.; Selvaggi, G.; Albergo, S.; Chiorboli, M.; Costa, S.; Galanti, M.; Giudice, N.; Guardone, N.; Noto, F.; Potenza, R.; Saizu, M.A.; Sparti, V.; Sutera, C.; Tricomi, A.; Tuve, C.; Brianzi, M.; Civinini, C.; Maletta, F.; Manolescu, F.; Meschini, M.; Paoletti, S.; Sguazzoni, G.; Broccolo, B.; Ciulli, V.; D'Alessandro, R.; Focardi, E.; Frosali, S.; Genta, C.; Landi, G.; Lenzi, P.; Macchiolo, A.; Magini, N.; Parrini, G.; Scarlini, E.; Cerati, G.; Azzi, P.; Bacchetta, N.; Candelori, A.; Dorigo, T.; Kaminsky, A.; Karaevski, S.; Khomenkov, V.; Reznikov, S.; Tessaro, M.; Bisello, D.; De Mattia, M.; Giubilato, P.; Loreti, M.; Mattiazzo, S.; Nigro, M.; Paccagnella, A.; Pantano, D.; Pozzobon, N.; Tosi, M.; Bilei, G.M.; Checcucci, B.; Fano, L.; Servoli, L.; Ambroglini, F.; Babucci, E.; Benedetti, D.; Biasini, M.; Caponeri, B.; Covarelli, R.; Giorgi, M.; Lariccia, P.; Mantovani, G.; Marcantonini, M.; Postolache, V.; Santocchia, A.; Spiga, D.; Bagliesi, G.; Balestri, G.; Berretta, L.; Bianucci, S.; Boccali, T.; Bosi, F.; Bracci, F.; Castaldi, R.; Ceccanti, M.; Cecchi, R.; Cerri, C.; Cucoanes, A .S.; Dell'Orso, R.; Dobur, D.; Dutta, S.; Giassi, A.; Giusti, S.; Kartashov, D.; Kraan, A.; Lomtadze, T.; Lungu, G.A.; Magazzu, G.; Mammini, P.; Mariani, F.; Martinelli, G.; Moggi, A.; Palla, F.; Palmonari, F.; Petragnani, G.; Profeti, A.; Raffaelli, F.; Rizzi, D.; Sanguinetti, G.; Sarkar, S.; Sentenac, D.; Serban, A.T.; Slav, A.; Soldani, A.; Spagnolo, P.; Tenchini, R.; Tolaini, S.; Venturi, A.; Verdini, P.G.; Vos, M.; Zaccarelli, L.; Avanzini, C.; Basti, A.; Benucci, L.; Bocci, A.; Cazzola, U.; Fiori, F.; Linari, S.; Massa, M.; Messineo, A.; Segneri, G.; Tonelli, G.; Azzurri, P.; Bernardini, J.; Borrello, L.; Calzolari, F.; Foa, L.; Gennai, S.; Ligabue, F.; Petrucciani, G.; Rizzi, A.; Yang, Z.; Benotto, F.; Demaria, N.; Dumitrache, F.; Farano, R.; Borgia, M.A.; Castello, R.; Costa, M.; Migliore, E.; Romero, A.; Abbaneo, D.; Abbas, M.; Ahmed, I.; Akhtar, I.; Albert, E.; Bloch, C.; Breuker, H.; Butt, S.; Buchmuller, O.; Cattai, A.; Delaere, C.; Delattre, M.; Edera, L.M.; Engstrom, P.; Eppard, M.; Gateau, M.; Gill, K.; Giolo-Nicollerat, A.-S.; Grabit, R.; Honma, A.; Huhtinen, M.; Kloukinas, K.; Kortesmaa, J.; Kottelat, L.J.; Kuronen, A.; Leonardo, N.; Ljuslin, C.; Mannelli, M.; Masetti, L.; Marchioro, A.; Mersi, S.; Michal, S.; Mirabito, L.; Muffat-Joly, J.; Onnela, A.; Paillard, C.; Pal, I.; Pernot, J.F.; Petagna, P.; Petit, P.; Piccut, C.; Pioppi, M.; Postema, H.; Ranieri, R.; Ricci, D.; Rolandi, G.; Ronga, F.; Sigaud, C.; Syed, A.; Siegrist, P.; Tropea, P.; Troska, J.; Tsirou, A.; Vander Donckt, M.; Vasey, F.; Alagoz, E.; Amsler, Claude; Chiochia, V.; Regenfus, Christian; Robmann, P.; Rochet, J.; Rommerskirchen, T.; Schmidt, A.; Steiner, S.; Wilke, L.; Church, I.; Cole, J.; Coughlan, J.; Gay, A.; Taghavi, S.; Tomalin, I.; Bainbridge, R.; Cripps, N.; Fulcher, J.; Hall, G.; Noy, M.; Pesaresi, M.; Radicci, V.; Raymond, D.M.; Sharp, P.; Stoye, M.; Wingham, M.; Zorba, O.; Goitom, I.; Hobson, P.R.; Reid, I.; Teodorescu, L.; Hanson, G.; Jeng, G.-Y.; Liu, H.; Pasztor, G.; Satpathy, A.; Stringer, R.; Mangano, B.; Affolder, K.; Affolder, T.; Allen, A.; Barge, D.; Burke, S.; Callahan, D.; Campagnari, C.; Crook, A.; D'Alfonso, M.; Dietch, J.; Garberson, Jeffrey Ford; Hale, D.; Incandela, H.; Incandela, J.; Jaditz, S.; Kalavase, P.; Kreyer, S.; Kyre, S.; Lamb, J.; Mc Guinness, C.; Mills, C.; Nguyen, H.; Nikolic, M.; Lowette, S.; Rebassoo, F.; Ribnik, J.; Richman, J.; Rubinstein, N.; Sanhueza, S.; Shah, Y.; Simms, L.; Staszak, D.; Stoner, J.; Stuart, D.; Swain, S.; Vlimant, J.-R.; White, D.; Ulmer, K.A.; Wagner, S.R.; Bagby, L.; Bhat, P.C.; Burkett, K.; Cihangir, S.; Gutsche, O.; Jensen, H.; Johnson, M.; Luzhetskiy, N.; Mason, D.; Miao, T.; Moccia, S.; Noeding, C.; Ronzhin, A.; Skup, E.; Spalding, W.J.; Spiegel, L.; Tkaczyk, S.; Yumiceva, F.; Zatserklyaniy, A.; Zerev, E.; Anghel, I.; Bazterra, V.E.; Gerber, C.E.; Khalatian, S.; Shabalina, E.; Baringer, Philip S.; Bean, A.; Chen, J.; Hinchey, C.; Martin, C.; Moulik, T.; Robinson, R.; Gritsan, A.V.; Lae, C.K.; Tran, N.V.; Everaerts, P.; Hahn, K.A.; Harris, P.; Nahn, S.; Rudolph, M.; Sung, K.; Betchart, B.; Demina, R.; Gotra, Y.; Korjenevski, S.; Miner, D.; Orbaker, D.; Christofek, L.; Hooper, R.; Landsberg, G.; Nguyen, D.; Narain, M.; Speer, T.; Tsang, K.V.

    2009-01-01

    The subsystems of the CMS silicon strip tracker were integrated and commissioned at the Tracker Integration Facility (TIF) in the period from November 2006 to July 2007. As part of the commissioning, large samples of cosmic ray data were recorded under various running conditions in the absence of a magnetic field. Cosmic rays detected by scintillation counters were used to trigger the readout of up to 15% of the final silicon strip detector, and over 4.7 million events were recorded. This document describes the cosmic track reconstruction and presents results on the performance of track and hit reconstruction as from dedicated analyses.

  5. Alignment of the CMS Silicon Strip Tracker during stand-alone Commissioning

    Adam, W.; Dragicevic, M.; Friedl, M.; Fruhwirth, R.; Hansel, S.; Hrubec, J.; Krammer, M.; Oberegger, M.; Pernicka, M.; Schmid, S.; Stark, R.; Steininger, H.; Uhl, D.; Waltenberger, W.; Widl, E.; Van Mechelen, P.; Cardaci, M.; Beaumont, W.; de Langhe, E.; de Wolf, E.A.; Delmeire, E.; Hashemi, M.; Bouhali, O.; Charaf, O.; Clerbaux, B.; Dewulf, J.-P.; Elgammal, S.; Hammad, G.; de Lentdecker, G.; Marage, P.; Vander Velde, C.; Vanlaer, P.; Wickens, J.; Adler, V.; Devroede, O.; De Weirdt, S.; D'Hondt, J.; Goorens, R.; Heyninck, J.; Maes, J.; Mozer, Matthias Ulrich; Tavernier, S.; Van Lancker, L.; Van Mulders, P.; Villella, I.; Wastiels, C.; Bonnet, J.-L.; Bruno, G.; De Callatay, B.; Florins, B.; Giammanco, A.; Gregoire, G.; Keutgen, Th.; Kcira, D.; Lemaitre, V.; Michotte, D.; Militaru, O.; Piotrzkowski, K.; Quertermont, L.; Roberfroid, V.; Rouby, X.; Teyssier, D.; daubie, E.; Anttila, E.; Czellar, S.; Engstrom, P.; Harkonen, J.; Karimaki, V.; Kostesmaa, J.; Kuronen, A.; Lampen, T.; Linden, T.; Luukka, P.-R.; Maenaa, T.; Michal, S.; Tuominen, E.; Tuominiemi, J.; Ageron, M.; Baulieu, G.; Bonnevaux, A.; Boudoul, G.; Chabanat, E.; Chabert, E.; Chierici, R.; Contardo, D.; Della Negra, R.; Dupasquier, T.; Gelin, G.; Giraud, N.; Guillot, G.; Estre, N.; Haroutunian, R.; Lumb, N.; Perries, S.; Schirra, F.; Trocme, B.; Vanzetto, S.; Agram, J.-L.; Blaes, R.; Drouhin, F.; Ernenwein, J.-P.; Fontaine, J.-C.; Berst, J.-D.; Brom, J.-M.; Didierjean, F.; Goerlach, U.; Graehling, P.; Gross, L.; Hosselet, J.; Juillot, P.; Lounis, A.; Maazouzi, C.; Olivetto, C.; Strub, R.; Van Hove, P.; Anagnostou, G.; Brauer, R.; Esser, H.; Feld, L.; Karpinski, W.; Klein, K.; Kukulies, C.; Olzem, J.; Ostapchuk, A.; Pandoulas, D.; Pierschel, G.; Raupach, F.; Schael, S.; Schwering, G.; Sprenger, D.; Thomas, M.; Weber, M.; Wittmer, B.; Wlochal, M.; Beissel, F.; Bock, E.; Flugge, G.; Gillissen, C.; Hermanns, T.; Heydhausen, D.; Jahn, D.; Kaussen, G.; Linn, A.; Perchalla, L.; Poettgens, M.; Pooth, O.; Stahl, A.; Zoeller, M.H.; Buhmann, P.; Butz, E.; Flucke, G.; Hamdorf, R.; Hauk, J.; Klanner, R.; Pein, U.; Schleper, P.; Steinbruck, G.; Blum, P.; De Boer, W.; Dierlamm, A.; Dirkes, G.; Fahrer, M.; Frey, M.; Furgeri, A.; Hartmann, F.; Heier, S.; Hoffmann, K.-H.; Kaminski, J.; Ledermann, B.; Liamsuwan, T.; Muller, S.; Muller, Th.; Schilling, F.-P.; Simonis, H.-J.; Steck, P.; Zhukov, V.; Cariola, P.; De Robertis, G.; Ferorelli, R.; Fiore, L.; Preda, M.; Sala, G.; Silvestris, L.; Tempesta, P.; Zito, G.; Creanza, D.; De Filippis, N.; De Palma, M.; Giordano, D.; Maggi, G.; Manna, N.; My, S.; Selvaggi, G.; Albergo, S.; Chiorboli, M.; Costa, S.; Galanti, M.; Giudice, N.; Guardone, N.; Noto, F.; Potenza, R.; Saizu, M.A.; Sparti, V.; Sutera, C.; Tricomi, A.; Tuve, C.; Brianzi, M.; Civinini, C.; Maletta, F.; Manolescu, F.; Meschini, M.; Paoletti, S.; Sguazzoni, G.; Broccolo, B.; Ciulli, V.; D'Alessandro, R.; Focardi, E.; Frosali, S.; Genta, C.; Landi, G.; Lenzi, P.; Macchiolo, A.; Magini, N.; Parrini, G.; Scarlini, E.; Cerati, G.; Azzi, P.; Bacchetta, N.; Candelori, A.; Dorigo, T.; Kaminsky, A.; Karaevski, S.; Khomenkov, V.; Reznikov, S.; Tessaro, M.; Bisello, D.; De Mattia, M.; Giubilato, P.; Loreti, M.; Mattiazzo, S.; Nigro, M.; Paccagnella, A.; Pantano, D.; Pozzobon, N.; Tosi, M.; Bilei, G.M.; Checcucci, B.; Fano, L.; Servoli, L.; Ambroglini, F.; Babucci, E.; Benedetti, D.; Biasini, M.; Caponeri, B.; Covarelli, R.; Giorgi, M.; Lariccia, P.; Mantovani, G.; Marcantonini, M.; Postolache, V.; Santocchia, A.; Spiga, D.; Bagliesi, G.; Balestri, G.; Berretta, L.; Bianucci, S.; Boccali, T.; Bosi, F.; Bracci, F.; Castaldi, R.; Ceccanti, M.; Cecchi, R.; Cerri, C.; Cucoanes, A.S.; Dell'Orso, R.; Dobur, D.; Dutta, S.; Giassi, A.; Giusti, S.; Kartashov, D.; Kraan, A.; Lomtadze, T.; Lungu, G.A.; Magazzu, G.; Mammini, P.; Mariani, F.; Martinelli, G.; Moggi, A.; Palla, F.; Palmonari, F.; Petragnani, G.; Profeti, A.; Raffaelli, F.; Rizzi, D.; Sanguinetti, G.; Sarkar, S.; Sentenac, D.; Serban, A.T.; Slav, A.; Soldani, A.; Spagnolo, P.; Tenchini, R.; Tolaini, S.; Venturi, A.; Verdini, P.G.; Vos, M.; Zaccarelli, L.; Avanzini, C.; Basti, A.; Benucci, L.; Bocci, A.; Cazzola, U.; Fiori, F.; Linari, S.; Massa, M.; Messineo, A.; Segneri, G.; Tonelli, G.; Azzurri, P.; Bernardini, J.; Borrello, L.; Calzolari, F.; Foa, L.; Gennai, S.; Ligabue, F.; Petrucciani, G.; Rizzi, A.; Yang, Z.; Benotto, F.; Demaria, N.; Dumitrache, F.; Farano, R.; Borgia, M.A.; Castello, R.; Costa, M.; Migliore, E.; Romero, A.; Abbaneo, D.; Abbas, M.; Ahmed, I.; Akhtar, I.; Albert, E.; Bloch, C.; Breuker, H.; Butt, S.; Buchmuller, O.; Cattai, A.; Delaere, C.; Delattre, M.; Edera, L.M.; Engstrom, P.; Eppard, M.; Gateau, M.; Gill, K.; Giolo-Nicollerat, A.-S.; Grabit, R.; Honma, A.; Huhtinen, M.; Kloukinas, K.; Kortesmaa, J.; Kottelat, L.J.; Kuronen, A.; Leonardo, N.; Ljuslin, C.; Mannelli, M.; Masetti, L.; Marchioro, A.; Mersi, S.; Michal, S.; Mirabito, L.; Muffat-Joly, J.; Onnela, A.; Paillard, C.; Pal, I.; Pernot, J.F.; Petagna, P.; Petit, P.; Piccut, C.; Pioppi, M.; Postema, H.; Ranieri, R.; Ricci, D.; Rolandi, G.; Ronga, F.; Sigaud, C.; Syed, A.; Siegrist, P.; Tropea, P.; Troska, J.; Tsirou, A.; Vander Donckt, M.; Vasey, F.; Alagoz, E.; Amsler, Claude; Chiochia, V.; Regenfus, Christian; Robmann, P.; Rochet, J.; Rommerskirchen, T.; Schmidt, A.; Steiner, S.; Wilke, L.; Church, I.; Cole, J.; Coughlan, J.; Gay, A.; Taghavi, S.; Tomalin, I.; Bainbridge, R.; Cripps, N.; Fulcher, J.; Hall, G.; Noy, M.; Pesaresi, M.; Radicci, V.; Raymond, D.M.; Sharp, P.; Stoye, M.; Wingham, M.; Zorba, O.; Goitom, I.; Hobson, P.R.; Reid, I.; Teodorescu, L.; Hanson, G.; Jeng, G.-Y.; Liu, H.; Pasztor, G.; Satpathy, A.; Stringer, R.; Mangano, B.; Affolder, K.; Affolder, T.; Allen, A.; Barge, D.; Burke, S.; Callahan, D.; Campagnari, C.; Crook, A.; D'Alfonso, M.; Dietch, J.; Garberson, Jeffrey Ford; Hale, D.; Incandela, H.; Incandela, J.; Jaditz, S.; Kalavase, P.; Kreyer, S.; Kyre, S.; Lamb, J.; Mc Guinnessr, C.; Mills, C.; Nguyen, H.; Nikolic, M.; Lowette, S.; Rebassoo, F.; Ribnik, J.; Richman, J.; Rubinstein, N.; Sanhueza, S.; Shah, Y.; Simms, L.; Staszak, D.; Stoner, J.; Stuart, D.; Swain, S.; Vlimant, J.-R.; White, D.; Ulmer, K.A.; Wagner, S.R.; Bagby, L.; Bhat, P.C.; Burkett, K.; Cihangir, S.; Gutsche, O.; Jensen, H.; Johnson, M.; Luzhetskiy, N.; Mason, D.; Miao, T.; Moccia, S.; Noeding, C.; Ronzhin, A.; Skup, E.; Spalding, W.J.; Spiegel, L.; Tkaczyk, S.; Yumiceva, F.; Zatserklyaniy, A.; Zerev, E.; Anghel, I.; Bazterra, V.E.; Gerber, C.E.; Khalatian, S.; Shabalina, E.; Baringer, Philip S.; Bean, A.; Chen, J.; Hinchey, C.; Martin, C.; Moulik, T.; Robinson, R.; Gritsan, A.V.; Lae, C.K.; Tran, N.V.; Everaerts, P.; Hahn, K.A.; Harris, P.; Nahn, S.; Rudolph, M.; Sung, K.; Betchart, B.; Demina, R.; Gotra, Y.; Korjenevski, S.; Miner, D.; Orbaker, D.; Christofek, L.; Hooper, R.; Landsberg, G.; Nguyen, D.; Narain, M.; Speer, T.; Tsang, K.V.

    2009-01-01

    The results of the CMS tracker alignment analysis are presented using the data from cosmic tracks, optical survey information, and the laser alignment system at the Tracker Integration Facility at CERN. During several months of operation in the spring and summer of 2007, about five million cosmic track events were collected with a partially active CMS Tracker. This allowed us to perform first alignment of the active silicon modules with the cosmic tracks using three different statistical approaches; validate the survey and laser alignment system performance; and test the stability of Tracker structures under various stresses and temperatures ranging from +15C to -15C. Comparison with simulation shows that the achieved alignment precision in the barrel part of the tracker leads to residual distributions similar to those obtained with a random misalignment of 50 (80) microns in the outer (inner) part of the barrel.

  6. Particulate matter concentrations in residences: an intervention study evaluating stand-alone filters and air conditioners.

    Batterman, S; Du, L; Mentz, G; Mukherjee, B; Parker, E; Godwin, C; Chin, J-Y; O'Toole, A; Robins, T; Rowe, Z; Lewis, T

    2012-06-01

    This study, a randomized controlled trial, evaluated the effectiveness of free-standing air filters and window air conditioners (ACs) in 126 low-income households of children with asthma. Households were randomized into a control group, a group receiving a free-standing HEPA filter placed in the child's sleeping area, and a group receiving the filter and a window-mounted AC. Indoor air quality (IAQ) was monitored for week-long periods over three to four seasons. High concentrations of particulate matter (PM) and carbon dioxide were frequently seen. When IAQ was monitored, filters reduced PM levels in the child's bedroom by an average of 50%. Filter use varied greatly among households and declined over time, for example, during weeks when pollutants were monitored, filter use was initially high, averaging 84±27%, but dropped to 63±33% in subsequent seasons. In months when households were not visited, use averaged only 34±30%. Filter effectiveness did not vary in homes with central or room ACs. The study shows that measurements over multiple seasons are needed to characterize air quality and filter performance. The effectiveness of interventions using free-standing air filters depends on occupant behavior, and strategies to ensure filter use should be an integral part of interventions. Environmental tobacco smoke (ETS) increased particulate matter (PM) levels by about 14 μg/m3 and was often detected using ETS-specific tracers despite restrictions on smoking in the house as reported on questionnaires administered to caregivers. PM concentrations depended on season, filter usage, relative humidity, air exchange ratios, number of children, outdoor PM levels, sweeping/dusting, and presence of a central air conditioner (AC). Free-standing air filters can be an effective intervention that provides substantial reductions in PM concentrations if the filters are used. However, filter use was variable across the study population and declined over the study duration, and thus strategies are needed to encourage and maintain use of filters. The variability in filter use suggests that exposure misclassification is a potential problem in intervention studies using filters. The installation of a room AC in the bedroom, intended to limit air exchange ratios, along with an air filter, did not lower PM levels more than the filter alone. © 2011 John Wiley & Sons A/S.

  7. A Voltage and Frequency Control Strategy for Stand-Alone Full Converter Wind Energy Conversion Systems

    Andrés Peña Asensio

    2018-02-01

    Full Text Available This paper addresses the design and analysis of a voltage and frequency control (VFC strategy for full converter (FC-based wind energy conversion systems (WECSs and its applicability for the supply of an isolated load. When supplying an isolated load, the role of the back-to-back converters in the FC must change with respect to a grid-connected application. Voltage and frequency are established by the FC line side converter (LSC, while the generator side converter (GSC is responsible for maintaining constant voltage in the DC link. Thus, the roles of the converters in the WECS are inverted. Under such control strategies, the LSC will automatically supply the load power and hence, in order to maintain a stable operation of the WECS, the wind turbine (WT power must also be controlled in a load-following strategy. The proposed VFC is fully modelled and a stability analysis is performed. Then, the operation of the WECS under the proposed VFC is simulated and tested on a real-time test bench, demonstrating the performance of the VFC for the isolated operation of the WECS.

  8. PV LED ENGINE characterization lab for stand alone light-to-light systems

    Poulsen, Peter Behrensdorff; Thorsteinsson, Sune; Lindén, Johannes

    2015-01-01

    dimming functions for reliable lighting. A barrier for exploiting use of standalone solar lighting for the urban environment seem to be lack of knowledge and lack of available tools for proper dimensioning. In this work the development of powerful dimensioning tool is described and initial measurements...... are presented. Furthermore, a laboratory has been build to characterize these systems up to 200 Wp from “nose to tail” in great details to support improvement of the systems and to make accurate field performance predictions by the dimensioning tool....

  9. Rancang Bangun Stand-Alone Automatic Rain Gauge (ARG Berbasis Panel Surya

    Zaenal Arifin

    2017-11-01

    Full Text Available Automatic Rain Gauge (ARG digunakan untuk memonitor curah hujan di suatu wilayah. ARG bekerja dengan menggunakan mikrokontroller sebagai prosesing unit dan merupakan sebuah embedded sistem (sistem yang berdiri sendiri. ARG tidak hanya diletakan pada stasiun pemantauan Badan Meteorologi, Klimatologi dan Geofisika (BMKG, namun ARG juga diletakan di daerah terpencil yang jauh dari jaringan listrik. Hal tersebut menjadi masalah karena ARG membutuhkan sumber energi listrik untuk dapat bekerja. Berdasarkan spesifikasinya, ARG membutuhkan mikrokontroller yang rendah dalam penggunaan daya serta memiliki cukup memory sebagai tempat penyimpanan data sementara. Salah satu jenis mikrokrontroller yang memenuhi spesifikasi tersebut adalah MSP430FR5969. Dari penelitian yang telah dilakukan, didapatkan hasil konsumsi daya rata – rata yang dibutuhkan oleh ARG sebesar 0.23 watt. Dengan memanfaatkan panel surya sebesar 20 watt yang dilengkapi dengan maximum power point tracking (MPPT sebagai sumber energi listrik, dapat menghasilkan daya 5,5 watt hingga 7,2 watt. Dengan perbandingan data konsumsi energi dan data yang dihasilkan dari solar panel panel, maka ARG memiliki sumber listrik mandiri untuk memenuhi kebutuhannya.

  10. Investigation of heating and cooling in a stand-alone high temperature PEM fuel cell system

    Zhang, Caizhi; Yu, Tao; Yi, Jun; Liu, Zhitao; Raj, Kamal Abdul Rasheedj; Xia, Lingchao; Tu, Zhengkai; Chan, Siew Hwa

    2016-01-01

    Highlights: • Heating-up and cooling-down processes of HT-PEMFC are the mainly interested topics. • Dynamic behaviours, power and energy demand of the heating and cooling was studied. • Hybrid system based on LiFeYPO_4 battery for heating and cooling is built and tested. • The concept of combining different heating sources together is recommended. - Abstract: One key issue pertaining to the cold-start of High temperature PEM fuel cell (HT-PEMFC) is the requirement of high amount of thermal energy for heating up the stack to a temperature of 120 °C or above before it can generate electricity. Furthermore, cooling down the stack to a certain temperature (e.g. 50 °C) is necessary before stopping. In this study, the dynamic behaviours, power and energy demand of a 6 kW liquid cooled HT-PEMFC stack during heating-up, operation and cooling-down were investigated experimentally. The dynamic behaviours of fuel cell under heating-up and cooling-down processes are the mainly interested topics. Then a hybridisation of HT-PEMFC with Li-ion battery to demonstrate the synergistic effect on dynamic behaviour was conducted and validated for its feasibility. At last, the concept of combining different heating sources together is analysed to reduce the heating time of the HT-PEMFC as well.

  11. Analysis and optimization of hybrid excitation permanent magnet synchronous generator for stand-alone power system

    Wang, Huijun, E-mail: huijun024@gmail.com [School of Instrumentation Science and Opto-electronics Engineering, Beihang University (China); Qu, Zheng; Tang, Shaofei; Pang, Mingqi [School of Instrumentation Science and Opto-electronics Engineering, Beihang University (China); Zhang, Mingju [Shanghai Aerospace Control Technology Institute, Shanghai (China)

    2017-08-15

    Highlights: • One novel permanent magnet generator structure has been proposed to reduce voltage regulation ratio. • Finite element method and equivalent circuit methods are both employed to realize rapid generator design. • Design of experiment (DOE) method is used to optimize permanent magnet shape for reduce voltage waveform distortion. • The obtained analysis and experiment results verify the proposed design methods. - Abstract: In this paper, electromagnetic design and permanent magnet shape optimization for permanent magnet synchronous generator with hybrid excitation are investigated. Based on generator structure and principle, design outline is presented for obtaining high efficiency and low voltage fluctuation. In order to realize rapid design, equivalent magnetic circuits for permanent magnet and iron poles are developed. At the same time, finite element analysis is employed. Furthermore, by means of design of experiment (DOE) method, permanent magnet is optimized to reduce voltage waveform distortion. Finally, the validity of proposed design methods is validated by the analytical and experimental results.

  12. Fuzzy Secondary Controller for Autonomous Stand-alone and Grid-connected AC Microgrid

    Neves, Rodolpho V. A.; Machado, Ricardo Q.; Oliveira, Vilma A.

    2016-01-01

    The present paper adresses the AC microgrid control issue using the hierarchical control structure and droop controllers for load sharing. Once the droop controllers impose an operation with frequency and voltage deviations, depending on the load and droop parameters, a hierarchical control...... structure must be added to change the droop controller operating points. The hierarchical controllers operate with local measurements and shared signals from communication links among the distributed generation systems connected to the microgrid. Depending on the geographical size of the microgrid......, the communication links can be economically unviable. This paper thus proposes a fuzzy secondary controller for AC microgrids to reduce the link communication dependency by using only local measurements. The simulation results show that the deviations as happened with the conventional secondary controllers can...

  13. Simulation of a stand-alone renewable hydrogen system for residential supply

    Martín Hervello

    2014-01-01

    Full Text Available La simulación por ordenador es un primer paso lógico previo a la realización de un proyecto de una construcción física además de ser una herramienta para el diseño de redes de energía. Los sistemas combinados son una solución para mejorar la disponibilidad de la energía suministrada con medios renovables. El principal inconveniente de las fuentes de energías renovables es su naturaleza altamente estacional, con grandes variaciones en el tiempo que pueden impedir el uso como base de consumo y limitar las horas de máxima demanda. El objetivo de este trabajo es realizar simulaciones para comprobar la autosuficiencia energética de una vivienda unifamiliar en base a energías renovables (eólica, solar-fotovoltaica utilizando como medio de almacenamiento un sistema híbrido de baterías e hidrógeno. Para ello se ha utilizado el programa Simulink®-Matlab® teniendo en cuenta los datos meteorológicos proporcionados por METEO-Galicia. El modelo puede ser aplicado para determinar la viabilidad de implementar una red energética en regiones específicas, y predecir el flujo de energía y el comportamiento del sistema durante todo el año.

  14. Photovoltaic OLED Driver for Low-Power Stand-Alone Light-to-Light Systems

    Ploug, Rasmus Overgaard; Knott, Arnold

    2016-01-01

    of a three-port-converter for this purpose optimized for the specifications for driving an Organic Light Emitting Diode (OLED) panel intended for lighting purposes. By using a three-port-converter, featuring shared components for each conversion mode, the converter reaches 97 % efficiency at 1.8 W during...... conversion from photovoltaic panel to the battery, and 97 % in the area 1.4 W to 2 W for power delivery to the OLED....

  15. Stand alone power system coupling a PV field and a fuel cell: first experimental results

    Busquet, S.; Labbe, J.; Leroux, P.; Metkemeijer, R.; Mayer, D. [ENSMP-CENERG, Sophia Antipolis (France)

    2003-07-01

    The purpose of the work, through the PVFC-SYS project, is to optimise the operation of a system coupling a photovoltaic field, an electrolyser, a gas storage, a fuel cell and a power management unit. A test bench is at present finalised in the Laboratory. All components have been selected for an optimal, automatic, safe and reliable operation of the complete system. Fully instrumented, this test bench furnishes new data concerning each component and the complete system behaviour for variable real weather conditions and different load demands. The paper describes the test bench, the simulation tool based on empirical model fitted to the component experimental data and the complete system performance for different load profiles along a year of operation. (orig.)

  16. Study on unitized inverter with photovoltaic grid-connected and stand-alone functions

    Wang, Haining; Su, Jianhui; Ding, Ming [Hefei University of Technology, Hefei (China)

    2008-07-01

    The main circuit and algorithm of unitized single phase inverter are presented, in which photovoltaic (PV) grid-connected algorithm, independency sine inverter algorithm and storage battery charge administer are all integrated basing on DSP (Digital Signal Processor). The control system identifies utility failure initiatively and then switches to independency power supply automatically. The methods of charging battery are multiform. Basing on material term to use utility or solar array to charge can optimize charge efficiency, assure the capacitance of battery and prolong life-span of battery. In addition, some results are offered basing on the prototype of a 2.5kW single phase inverter. (orig.)

  17. Development of a stand-alone microcomputer based DOE contractor generic radiation worker safety course

    Klos, D.B.; Gardner, P.R.

    1985-01-01

    Westinghouse Hanford Company (WHC) has developed Computer Based Training (CBT) materials for radiation and industrial safety. First released for general Fast Flux Test Facility in November, 1984. This course has now been taken by nearly 350 people. Completion times for new personnel average around eight hours. The next project undertaken was construction of a Radiation Worker Safety course generic enough for use by all contractors at the Hanford site. The design process of the Hanford site course indicated that the quantity of ''DOE common material'' may be sufficient to warrant consideration of a larger target population. Specifically, the course will be designed to run on an IBM-PC or compatible computer having 256K RAM, a standard IBM color graphics card or equivalent, a color graphics monitor, and two floppy disk drives or one hard disk. The target student population includes those who routinely work in Radiation Areas, especially crafts people. We are not targeting Health Physics personnel, except, possibly, for introductory training, nor are we directing the course toward ''casual'' or escorted workers

  18. The children left to stand alone | Roalkvam | African Journal of AIDS ...

    Drawing upon ethnographic fieldwork in Seke, a semi-rural area outside Harare, Zimbabwe, this paper explores the social mechanism behind the seeming invisibility of children left on their own and how this form of 'invisibility' challenges established notions of childhood, parenthood, kinship, and community. It argues that ...

  19. Comparing Memory-Efficient Genome Assemblers on Stand-Alone and Cloud Infrastructures

    Kleftogiannis, Dimitrios A.; Kalnis, Panos; Bajic, Vladimir B.

    2013-01-01

    methodologies, we propose two general assembly strategies that can improve short-read assembly approaches and result in reduction of the memory footprint. Finally, we discuss the possibility of utilizing cloud infrastructures for genome assembly and we comment

  20. Kajian Pemanfaatan Stand Alone Photovoltaic System Untuk Penerangan Jalan Umum Di Pulau Nusa Penida

    I.W. Yudi Martha Wiguna

    2012-12-01

    Full Text Available   Nusa Penida merupakan sebuah pulau di tenggara pulau Bali dengan jumlah penduduk 47.448 jiwa. Ketersediaan daya pembangkit PLN di pulau Nusa Penida adalah sebesar 3200 kW. Dengan beban puncak sebesar 2530 kW maka cadangan listrik saat ini hanya sebesar 670 kW. Hal itu menyebabkan krisis listrik sangat terasa bagi masyarakat di daerah terpencil seperti di Pulau Nusa Penida. Saat ini salah satu solusi yang memungkinkan adalah mengembangkan sumber energi terbarukan. Di Pulau Nusa Penida sudah dikembangkan PLTS. Bahkan PLTS di Pulau Nusa Penida dikembangkan juga pada sistem penerangan jalan umum. Pada penelitian ini dilakukan analisa teknis dan biaya untuk mengetahui kelayakan Sistem PJU-TS tersebut. Pada analisa teknis dilakukan pengukuran output tegangan dan arus dari PV Panel ke Charger Controller, dari Charger Controller ke baterai dan ke beban. Analisa teknis menghasilkan bahwa penyebab kerusakan baterai karena kapasitas pembangkitan tidak sebanding dengan kebutuhan kapasitas beban PJU-TS. Dengan kapasitas baterai yang terus kecil akan menyebabkan kerusakan pada baterai. Selain itu karena usia baterai yang sudah lama. Analisa biaya dilakukan dengan 3 skenario dengan tingkat IRR yang ingin dicapai sebesar 10, 11, dan 12 %. Dihasilkan harga jual yang pantas untuk energi listrik PJU-TS Nusa Penida berkisar antara Rp.29.194,00 s/d Rp.31.585,00 per kWh.

  1. SAMAC program: the computer support for a stand-alone monitoring and control system

    Logg, C.A.

    1979-12-01

    The high energy physics experiments at SLAC require constant monitoring and control of the numerous components contained in the particle detection apparatus. This paper describes a basic hardware configuration and operating system which have been designed and implemented to satisfy the monitoring and control requirements of the many different setups used in these high energy physics experiments. It is based on the LSI-11 microprocessor with up to one million words of RAM and EPROM which are interchangeably mappable into the normal LSI-11 RAM/EPROM address space of 28K words. The entire system is modular in hardware and software so that it can easily be tailored to an individual experiment. The human interface is such that little training is required for effective use of the system

  2. Stand-alone and Interdisciplinary Course Design for Engineering Education for Sustainable Development

    Arsat, M.; Holgaard, Jette Egelund; de Graaff, Erik

    discipline or to fit across programmes. At Aalborg University (AAU), Denmark, which has a long tradition of problem based learning (PBL), a comprehensive sustainability course has been introduced to fit all students not at least across programmes but also across faculties of engineering, humanities...

  3. Battery Storage Technologies for Electrical Applications: Impact in Stand-Alone Photovoltaic Systems

    Daniel Akinyele; Juri Belikov; Yoash Levron

    2017-01-01

    Batteries are promising storage technologies for stationary applications because of their maturity, and the ease with which they are designed and installed compared to other technologies. However, they pose threats to the environment and human health. Several studies have discussed the various battery technologies and applications, but evaluating the environmental impact of batteries in electrical systems remains a gap that requires concerted research efforts. This study first presents an ove...

  4. Analysis and optimization of hybrid excitation permanent magnet synchronous generator for stand-alone power system

    Wang, Huijun; Qu, Zheng; Tang, Shaofei; Pang, Mingqi; Zhang, Mingju

    2017-01-01

    Highlights: • One novel permanent magnet generator structure has been proposed to reduce voltage regulation ratio. • Finite element method and equivalent circuit methods are both employed to realize rapid generator design. • Design of experiment (DOE) method is used to optimize permanent magnet shape for reduce voltage waveform distortion. • The obtained analysis and experiment results verify the proposed design methods. - Abstract: In this paper, electromagnetic design and permanent magnet shape optimization for permanent magnet synchronous generator with hybrid excitation are investigated. Based on generator structure and principle, design outline is presented for obtaining high efficiency and low voltage fluctuation. In order to realize rapid design, equivalent magnetic circuits for permanent magnet and iron poles are developed. At the same time, finite element analysis is employed. Furthermore, by means of design of experiment (DOE) method, permanent magnet is optimized to reduce voltage waveform distortion. Finally, the validity of proposed design methods is validated by the analytical and experimental results.

  5. X-ray microbeam stand-alone facility for cultured cells irradiation

    Bożek, Sebastian, E-mail: sebastian.bozek@yahoo.com [Jagiellonian University Medical College, Department of Pharmaceutical Biophysics, Krakow (Poland); Bielecki, Jakub; Wiecheć, Anna; Lekki, Janusz; Stachura, Zbigniew; Pogoda, Katarzyna; Lipiec, Ewelina; Tkocz, Konrad; Kwiatek, Wojciech M. [Institute of Nuclear Physics Polish Academy of Sciences, PL-31342 Krakow (Poland)

    2017-03-01

    Highlights: • An X-ray microbeam line for irradiation of living cultured cells was constructed. • A step by step explanation of working principles with engineering details, procedures and calculations is presented. • A model of beam and cell interaction is presented. • A method of uniform irradiation of living cells with an exact dose per a cell is presented. • Results of preliminary experiments are presented. - Abstract: The article describes an X-ray microbeam standalone facility dedicated for irradiation of living cultured cells. The article can serve as an advice for such facilities construction, as it begins from engineering details, through mathematical modeling and experimental procedures, ending up with preliminary experimental results and conclusions. The presented system consists of an open type X-ray tube with microfocusing down to about 2 μm, an X-ray focusing system with optical elements arranged in the nested Kirckpatrick-Baez (or Montel) geometry, a sample stand and an optical microscope with a scientific digital CCD camera. For the beam visualisation an X-ray sensitive CCD camera and a spectral detector are used, as well as a scintillator screen combined with the microscope. A method of precise one by one irradiation of previously chosen cells is presented, as well as a fast method of uniform irradiation of a chosen sample area. Mathematical models of beam and cell with calculations of kerma and dose are presented. The experiments on dose-effect relationship, kinetics of DNA double strand breaks repair, as well as micronuclei observation were performed on PC-3 (Prostate Cancer) cultured cells. The cells were seeded and irradiated on Mylar foil, which covered a hole drilled in the Petri dish. DNA lesions were visualised with γ-H2AX marker combined with Alexa Fluor 488 fluorescent dye.

  6. The Small, Stand-Alone Early College: Impact on High School Outcomes

    Glennie, Elizabeth; Unlu, Fatih; Furey, Jane

    2016-01-01

    North Carolina's Early College model is the subject of an IES-funded eleven-year longitudinal experimental study that utilized a lottery process to assign early college applicants to either treatment or control groups. This paper presents findings related to high school outcomes. The primary goal of the early college model is to increase the…

  7. The Small, Stand-Alone Early College: Impact on Postsecondary Outcomes

    Unlu, Fatih; Furey, Jane

    2016-01-01

    This paper presents results from the longitudinal experimental study conducted on North Carolina's early college model described in an earlier paper. The primary purpose of this paper is to present the impact of the early college model on outcomes related to postsecondary enrollment. The specific research questions driving this study include: (1)…

  8. Stand-alone error characterisation of microwave satellite soil moisture using a Fourier method

    Error characterisation of satellite-retrieved soil moisture (SM) is crucial for maximizing their utility in research and applications in hydro-meteorology and climatology. Error characteristics can provide insights for retrieval development and validation, and inform suitable strategies for data fus...

  9. A stand-alone track reconstruction algorithm for the scintillating fibre tracker at the LHCb upgrade

    Quagliani, Renato

    2017-01-01

    The LHCb upgrade detector project foresees the presence of a scintillating fiber tracker (SciFi) to be used during the LHC Run III, starting in 2020. The instantaneous luminosity will be increased up to $2\\times10^{33}$, five times larger than in Run II and a full software event reconstruction will be performed at the full bunch crossing rate by the trigger. The new running conditions, and the tighter timing constraints in the software trigger, represent a big challenge for track reconstruction. This poster presents the design and performance of a novel algorithm that has been developed to reconstruct track segments using solely hits from the SciFi. This algorithm is crucial for the reconstruction of tracks originating from long-lived particles such as $K_{S}^{0}$ and $\\Lambda$ and allows to greatly enhance the physics potential and capabilities of the LHCb upgrade when compared to its previous implementation.

  10. Comparing Memory-Efficient Genome Assemblers on Stand-Alone and Cloud Infrastructures

    Kleftogiannis, Dimitrios A.

    2013-09-27

    A fundamental problem in bioinformatics is genome assembly. Next-generation sequencing (NGS) technologies produce large volumes of fragmented genome reads, which require large amounts of memory to assemble the complete genome efficiently. With recent improvements in DNA sequencing technologies, it is expected that the memory footprint required for the assembly process will increase dramatically and will emerge as a limiting factor in processing widely available NGS-generated reads. In this report, we compare current memory-efficient techniques for genome assembly with respect to quality, memory consumption and execution time. Our experiments prove that it is possible to generate draft assemblies of reasonable quality on conventional multi-purpose computers with very limited available memory by choosing suitable assembly methods. Our study reveals the minimum memory requirements for different assembly programs even when data volume exceeds memory capacity by orders of magnitude. By combining existing methodologies, we propose two general assembly strategies that can improve short-read assembly approaches and result in reduction of the memory footprint. Finally, we discuss the possibility of utilizing cloud infrastructures for genome assembly and we comment on some findings regarding suitable computational resources for assembly.

  11. Experimental stand-alone self-excited induction generator driven by a diesel motor

    Mhamdi Taoufik

    2017-12-01

    Full Text Available This paper presents an experimental work to design and size a diesel generator (DG. The basic system is equipped with a 1.5 kW self-excited induction generator (SEIG, a diesel motor (DM, a static voltage compensator (SVC and controllers. A proportional integral controller is used to meet the requirement of the SEIG frequency regulation. A controlled voltage source is performed by using an SVC with a fuzzy controller, which adjusts voltage by varying the amount of the injected reactive power. An experimental set-up is used to identify the SEIG parameters and select the convenient bank of capacitors that minimize the SEIG starting up time and fix the convenient margin of voltage. The system has been tested by simulation using models implemented by Matlab/Simulink software. The simulation results confirm the efficiency of the proposed strategy of voltage regulation. Keywords: Diesel motor, SEIG, SVC, Voltage regulation, Frequency regulation

  12. SSTAR, a Stand-Alone Easy-To-Use Antimicrobial Resistance Gene Predictor.

    de Man, Tom J B; Limbago, Brandi M

    2016-01-01

    We present the easy-to-use Sequence Search Tool for Antimicrobial Resistance, SSTAR. It combines a locally executed BLASTN search against a customizable database with an intuitive graphical user interface for identifying antimicrobial resistance (AR) genes from genomic data. Although the database is initially populated from a public repository of acquired resistance determinants (i.e., ARG-ANNOT), it can be customized for particular pathogen groups and resistance mechanisms. For instance, outer membrane porin sequences associated with carbapenem resistance phenotypes can be added, and known intrinsic mechanisms can be included. Unique about this tool is the ability to easily detect putative new alleles and truncated versions of existing AR genes. Variants and potential new alleles are brought to the attention of the user for further investigation. For instance, SSTAR is able to identify modified or truncated versions of porins, which may be of great importance in carbapenemase-negative carbapenem-resistant Enterobacteriaceae. SSTAR is written in Java and is therefore platform independent and compatible with both Windows and Unix operating systems. SSTAR and its manual, which includes a simple installation guide, are freely available from https://github.com/tomdeman-bio/Sequence-Search-Tool-for-Antimicrobial-Resistance-SSTAR-. IMPORTANCE Whole-genome sequencing (WGS) is quickly becoming a routine method for identifying genes associated with antimicrobial resistance (AR). However, for many microbiologists, the use and analysis of WGS data present a substantial challenge. We developed SSTAR, software with a graphical user interface that enables the identification of known AR genes from WGS and has the unique capacity to easily detect new variants of known AR genes, including truncated protein variants. Current software solutions do not notify the user when genes are truncated and, therefore, likely nonfunctional, which makes phenotype predictions less accurate. SSTAR users can apply any AR database of interest as a reference comparator and can manually add genes that impact resistance, even if such genes are not resistance determinants per se (e.g., porins and efflux pumps).

  13. Porous silicon with embedded tritium as a stand-alone prime power source for optoelectronic applications

    Tam, S.W.

    1997-01-01

    Disclosed is an illumination source comprising a porous silicon having a source of electrons on the surface and/or interstices thereof having a total porosity in the range of from about 50 v/o to about 90 v/o. Also disclosed are a tritiated porous silicon and a photovoltaic device and an illumination source of tritiated porous silicon. 1 fig

  14. Porous silicon with embedded tritium as a stand-alone prime power source for optoelectronic applications

    Tam, Shiu-Wing

    1997-01-01

    An illumination source comprising a porous silicon having a source of electrons on the surface and/or interticies thereof having a total porosity in the range of from about 50 v/o to about 90 v/o. Also disclosed are a tritiated porous silicon and a photovoltaic device and an illumination source of tritiated porous silicon.

  15. The Politics of Education: Why Stand-Alone Youth Work Degrees Matter

    Bessant, Judith

    2007-01-01

    While the demand in Australia for youth workers is growing, the education of youth workers in universities is being "rationalised" because these institutions have been fiscally squeezed by successive federal governments. What are the consequences for youth workers, young people and society as a whole if the move towards…

  16. Comparing memory-efficient genome assemblers on stand-alone and cloud infrastructures.

    Kleftogiannis, Dimitrios; Kalnis, Panos; Bajic, Vladimir B

    2013-01-01

    A fundamental problem in bioinformatics is genome assembly. Next-generation sequencing (NGS) technologies produce large volumes of fragmented genome reads, which require large amounts of memory to assemble the complete genome efficiently. With recent improvements in DNA sequencing technologies, it is expected that the memory footprint required for the assembly process will increase dramatically and will emerge as a limiting factor in processing widely available NGS-generated reads. In this report, we compare current memory-efficient techniques for genome assembly with respect to quality, memory consumption and execution time. Our experiments prove that it is possible to generate draft assemblies of reasonable quality on conventional multi-purpose computers with very limited available memory by choosing suitable assembly methods. Our study reveals the minimum memory requirements for different assembly programs even when data volume exceeds memory capacity by orders of magnitude. By combining existing methodologies, we propose two general assembly strategies that can improve short-read assembly approaches and result in reduction of the memory footprint. Finally, we discuss the possibility of utilizing cloud infrastructures for genome assembly and we comment on some findings regarding suitable computational resources for assembly.

  17. Single-crate stand-alone CAMAC control system for a negative ion source test facility

    Juras, R.C.; Ziegler, N.F.

    1979-01-01

    A single-crate CAMAC system was configured to control a negative ion source development facility at ORNL and control software was written for the crate microcomputer. The software uses inputs from a touch panel and a shaft encoder to control the various operating parameters of the test facility and uses the touch panel to display the operating status. Communication to and from the equipment at ion source potential is accomplished over optical fibers from an ORNL-built CAMAC module. A receiver at ion source potential stores the transmitted data and some of these stored values are then used to control discrete parameters of the ion source (i.e., power supply on or off). Other stored values are sent to a multiplexed digital-to-analog converter to provide analog control signals. A transmitter at ion source potential transmits discrete status information and several channels of analog data from an analog-to-digital converter back to the ground-potential receiver where it is stored to be read and displayed by the software

  18. An Approach for High-precision Stand-alone Positioning in a Dynamic Environment

    Halis Saka, M.; Metin Alkan, Reha; Ozpercin, Alişir

    2015-04-01

    In this study, an algorithm is developed for precise positioning in dynamic environment utilizing a single geodetic GNSS receiver using carrier phase data. In this method, users should start the measurement on a known point near the project area for a couple of seconds making use of a single dual-frequency geodetic-grade receiver. The technique employs iono-free carrier phase observations with precise products. The equation of the algorithm is given below; Sm(t(i+1))=SC(ti)+[ΦIF (t(i+1) )-ΦIF (ti)] where, Sm(t(i+1)) is the phase-range between satellites and the receiver, SC(ti) is the initial range computed from the initial known point coordinates and the satellite coordinates and ΦIF is the ionosphere-free phase measurement (in meters). Tropospheric path delays are modelled using the standard tropospheric model. To accomplish the process, an in-house program was coded and some functions were adopted from Easy-Suite available at http://kom.aau.dk/~borre/easy. In order to assess the performance of the introduced algorithm in a dynamic environment, a dataset from a kinematic test measurement was used. The data were collected from a kinematic test measurement in Istanbul, Turkey. In the test measurement, a geodetic dual-frequency GNSS receiver, Ashtech Z-Xtreme, was set up on a known point on the shore and a couple of epochs were recorded for initialization. The receiver was then moved to a vessel and data were collected for approximately 2.5 hours and the measurement was finalized on a known point on the shore. While the kinematic measurement on the vessel were carried out, another GNSS receiver was set up on a geodetic point with known coordinates on the shore and data were collected in static mode to calculate the reference trajectory of the vessel using differential technique. The coordinates of the vessel were calculated for each measurement epoch with the introduced method. With the purpose of obtaining more robust results, all coordinates were calculated once again by inversely, i.e. from the last epoch to the first one. In this way, the estimated coordinates were also controlled. The average of both computed coordinates were used as vessel coordinates and then compared with the known-coordinates those of geodetic receiver epoch by epoch. The results indicate that the calculated coordinates from the introduced method are consistent with the reference trajectory with an accuracy of about 1 decimeter. In contrast, the findings imply lower accuracy for height components with an accuracy of about 2 decimeters. This accuracy level meets the requirement of many applications including some marine applications, precise hydrographic surveying, dredging, attitude control of ships, buoys and floating platforms, marine geodesy, navigation and oceanography.

  19. Bifacial PV cell with reflector for stand-alone mast for sensor powering purposes

    Jakobsen, Michael L.; Thorsteinsson, Sune; Poulsen, Peter B.; Riedel, N.; Rødder, Peter M.; Rødder, Kristin

    2017-09-01

    Reflectors to bifacial PV-cells are simulated and prototyped in this work. The aim is to optimize the reflector to specific latitudes, and particularly northern latitudes. Specifically, by using minimum semiconductor area the reflector must be able to deliver the electrical power required at the condition of minimum solar travel above the horizon, worst weather condition etc. We will test a bifacial PV-module with a retroreflector, and compare the output with simulations combined with local solar data.

  20. Maximun power point tracker of photovoltaic s panels for stand alone systems

    Stoll, R; Manno, R

    2005-01-01

    The low energetic efficiency of photovoltaic s panels is known, in addition, due to the use of linear regulators, which dissipate an important bit of the generated energy, the efficiency of the photovoltaic systems is still smaller.Also, the I-V characteristic curve of the photovoltaic modules depends on the solar radiation and the own temperature; consequently, the maximum power point (Wp) changes permanently.In conclusion, to produce electricity with photovoltaic panels is very expensive. However due to preserve the environment this technology is widely used.With the purpose of optimizing the amount of energy produced by the photovoltaic system, two complementary methods are used.One is the Maximum Power Point Tracker (MPPT) system and the other one is the Solar Tracker system.The objective of this project is to reduce that cost increasing the amount of energy produced by the solar panels using a Maximum Power Point Tracker system.This device consists of a DC/DC buck converter of high performance, controlled by a PIC 16F873 micro controller; which carries out the conversions of the analogical signals of the solar array to digital signals (ADC), the PIC output digital signals to the PWM control of the power FET (DAC), and calculates the Duty Cycle (D) for the point of I-V curve where this product becomes maximum.Measurements for different loads and battery charges were made.With the obtained results, the comparisons with a conventional system were made, a greater cession of energy to the load is observed.The main conclusion of this work is: Using a MPPT device to making work the PV module during the greater possible time near the maximum power point, the efficiency of the photovoltaic systems can be increased

  1. Some hematological disorders among atomic bomb survivors. Presidential Address

    Watanabe, Susumu

    1977-01-01

    Focusing on their hematological disorders, the late radiation effects among Hiroshima and Nagasaki A-bomb survivors, including cytogenetic and cytological studies, are summarized and discussed. Because of personal research experience, the data were concentrated on the Hiroshima survivors

  2. HIGH ALTITUDES EFFECTS ON HEMATOLOGIC BLOOD PARAMETERS

    Hasim Rushiti

    2015-05-01

    Full Text Available The approach and the objective of this experiment are consistent with the determination of changes of blood parameters after the stay of the students at an altitude of 1800-2300 meters, for a ten-day long ski course. In this paper are included a total of 64 students of the Faculty of Sport Sciences in Prishtina, of the age group of 19-25 (the average age is 21. All students previously have undergone a medical check for TA, arterial pulse and respiratory rate. In particular, the health situation is of subjects was examined, then, all students, at the same time, gave blood for analysis. In this experiment, three main hematologic parameters were taken in consideration: such as hemoglobin, hematocrit and red blood cells. The same analyses were carried out after the 10-day stay at a high altitude. The results of the experiment have shown significant changes after the ten-day stay at high altitude, despite the previous results that show changes only after the twenty-day stay in such elevations.

  3. Leveraging cancer genome information in hematologic malignancies.

    Rampal, Raajit; Levine, Ross L

    2013-05-20

    The use of candidate gene and genome-wide discovery studies in the last several years has led to an expansion of our knowledge of the spectrum of recurrent, somatic disease alleles, which contribute to the pathogenesis of hematologic malignancies. Notably, these studies have also begun to fundamentally change our ability to develop informative prognostic schema that inform outcome and therapeutic response, yielding substantive insights into mechanisms of hematopoietic transformation in different tissue compartments. Although these studies have already had important biologic and translational impact, significant challenges remain in systematically applying these findings to clinical decision making and in implementing new technologies for genetic analysis into clinical practice to inform real-time decision making. Here, we review recent major genetic advances in myeloid and lymphoid malignancies, the impact of these findings on prognostic models, our understanding of disease initiation and evolution, and the implication of genomic discoveries on clinical decision making. Finally, we discuss general concepts in genetic modeling and the current state-of-the-art technology used in genetic investigation.

  4. 1976 Hanford Americium exposure incident: hematologic effects

    Ragan, H.A.; Mahaffey, J.A.; Breitenstein, B.D.

    1982-05-01

    Hematologic evaluation of an individual with an initial systemic body burden of approx. 200 μCi 241 Am revealed a significant (P < 0.01) reduction of total leukocytes, neutrophils, and lymphocytes. This effect on total leukocytes and neutrophils was evident approx. 30 days after exposure, appeared to stabilize at about 3 months after exposure, and remained at this lower level thorugh a 52-months observation period. The effect on lymphocytes was apparent by 3 days after exposure, stabilizing at approx. 50% of pre-exposure values for about 7 months, with a return to pre-exposure levels in the following 4 y. There was a progressive and significant (P < 0.001) decline in platelet counts during the 52-months postexposure period. The pattern of response in erythrocyte parameters was complex. Immediately after the accident, these values were less than the pre-exposure mean level; they gradually increased (P < 0.001) for approx. 2 y and then began a progressive decline (P < 0.001)

  5. Radiation therapy in patients with hematologic diseases

    Hennequin, C.; Maylin, C.

    1995-01-01

    Radiation therapy has a significant place in the treatment of hematologic diseases. Irradiation is a key component of the treatment strategy for Hodgkin's disease and has benefited from clinical studies aimed at improving its therapeutic index. There have been many recent improvements, in particular with regard to accuracy of techniques, imagery, dosimetry, and implementation of quality-control procedures. In localized non-Hodgkin's lymphoma, the gold-standard treatment is radiation therapy coupled with a short course of chemotherapy. In contrast, the place of irradiation in disseminated lymphomas remains to be defined. Prophylactic irradiation of the brain is still used in patients with acute lymphoblastic leukemia. Radiation therapy is of value as palliative treatment of bone lesions of myeloma, in chemo-resistant lymphomas, and in relapses of leukemia. Total body irradiation is a cumbersome but irreplaceable method, which has also benefited from recent clinical and biological studies. Optimal radiation therapy with the best possible therapeutic index requires adequate technological and human resources. (authors). 30 refs., 1 tab

  6. Hematologic effects of inhaled plutonium in beagles

    Ragan, H.A.; Buschbom, R.L.; Park, J.F.; Dagle, G.E.; Weller, R.E.

    1986-01-01

    Beagle dogs were exposed, by inhalation, 5 to 11 years ago, to aerosols of 239 PuO 2 , 238 PuO 2 , or 239 Pu(NO 3 ) 4 , at six dose levels resulting in initial lung burdens ranging from ∼2 to ∼5500 nCi. Translocation of the plutonium to extrapulmonary sites was related to the physical-chemical characteristics of the plutonium compound. The highly insoluble 239 PuO 2 was retained primarily in the lung and associated lymph nodes, whereas 239 Pu(NO 3 ) 4 was much more soluble and translocated relatively rapidly to the skeleton and other extrapulmonary tissues. The 238 PuO 2 was intermediate in solubility and translocation characteristics. The hematologic effects of plutonium inhalation were most pronounced on lymphocyte populations. Evidence suggests that these effects result from irradiation of lymphocytes via the pulmonary lymph nodes with insoluble 239 PuO 2 , and via these same lymph nodes, extrapulmonary lymph nodes, and bone marrow lymphocytes with the more soluble forms, i.e., 238 PuO 2 and 239 Pu(NO 3 ) 4 . There is no evidence suggesting that these exposures increase the risk of developing myeloid or lymphoid neoplasia. 8 refs., 4 figs., 3 tabs

  7. Methotrexate pharmacogenetics in Uruguayan adults with hematological malignant diseases.

    Giletti, Andrea; Vital, Marcelo; Lorenzo, Mariana; Cardozo, Patricia; Borelli, Gabriel; Gabus, Raúl; Martínez, Lem; Díaz, Lilian; Assar, Rodrigo; Rodriguez, María Noel; Esperón, Patricia

    2017-11-15

    Individual variability is among the causes of toxicity and interruption of treatment in acute lymphoblastic leukemia (ALL) and severe non-Hodgkin lymphoma (NHL) patients under protocols including Methotrexate (MTX): 2,4-diamino-N10-methyl propyl-glutamic acid. 41 Uruguayan patients were recruited. Gene polymorphisms involved in MTX pathway were analyzed and their association with treatment toxicities and outcome was evaluated. Genotype distribution and allele frequency were determined for SLC19A1 G 80 A, MTHFR C 677 T and A 1298 C, TYMS 28bp copy number variation, SLCO1B1 T 521 C, DHFR C -1610 G/T, DHFR C -680 A, DHFR A -317 G and DHFR 19bp indel. Multivariate analysis showed that DHFR -1610 G/T (OR=0.107, p=0.018) and MTHFR 677 T alleles (OR=0.12, p=0.026) had a strong protective effect against hematologic toxicity, while DHFR -1610 CC genotype increased this toxicity (OR=9, p=0.045). No more associations were found. The associations found between gene polymorphisms and toxicities in this small cohort are encouraging for a more extensive research to gain a better dose individualization in adult ALL and NHL patients. Besides, genotype distribution showed to be different from other populations, reinforcing the idea that genotype data from other populations should not be extrapolated to ours. Copyright © 2017 Elsevier B.V. All rights reserved.

  8. The effect of Ramadan fasting on hematological parameters

    Jafar Nasiri

    2016-12-01

    Full Text Available Background: Ramadan fasting is an obligation for many Muslims around the world who abstain from eating and drinking for one month, which has different medical and physiological effects, such as reducing blood pressure, lipid profile, blood glucose, and body weight. It has also been hypothesized that Ramadan fasting may induce some changes in the hematologic parameters. Thus, we aimed to investigate the effect of Ramadan fasting on blood cell count (CBC, and erythrocyte sedimentation rate (ESR. Methods: In the present study, 59 adult healthy individuals, who had completed one month of Ramadan fasting were included. Fasting blood samples were analyzed for ESR, hemoglobin (Hb, hematocrit (Hct, white blood cell (WBC, platelet count (PLT, mean corpuscular Volume (MCV and mean platelet volume (MPV, one day before, on the second and last week of Ramadan and one month after Ramadan (phase I , II, III,  and IV, respectively. Results: 34 men and 25 women with an age range of 15 to 24 years participated in the study. Mean ESR increased significantly (except phase IV, in comparison phase III. Mean Hb and Hct levels were significantly greater in phase III than phase I (P

  9. Triploidy in the hematology of jundia juveniles (Siluriformes: Heptapteridae)

    Fukushima, H; Bailone, RL; Weiss, LA; Martins, ML; Zaniboni-Filho, E

    2012-01-01

    This study compared the hematological characteristics of diploid and triploid of jundia, Rhamdia quelen juveniles, an important freshwater fish cultured in south Brazil. Hematological morphometry of erythrocytes were determined in blood smears under a light microscope. The blood was used to measure the number of red blood cells (RBC) with a hemocytometer Neubauer chamber, and the numbers of white blood cells (WBC) and thrombocytes that were obtained using an indirect method. The results showe...

  10. Utility of CRISPR/Cas9 systems in hematology research.

    Lucas, Daniel; O'Leary, Heather A; Ebert, Benjamin L; Cowan, Chad A; Tremblay, Cedric S

    2017-10-01

    Since the end of the 20th century, novel approaches have emerged to manipulate experimental models of hematological disorders so that they more accurately mirror what is observed in the clinical setting. Despite these technological advances, the characterization of crucial genes for benign or malignant hematological disorders remains challenging, given the dynamic nature of the hematopoietic system and the genetic heterogeneity of these disorders. To overcome this limitation, genome-editing technologies have been developed to manipulate the genome specifically via deletion, insertion, or modification of targeted loci. These technologies have progressed swiftly, allowing their common use to investigate genetic function in experimental hematology. Among them, homologous-recombination-mediated targeting technologies have facilitated the manipulation of specific loci by generating knock-out and knock-in models. Despite promoting significant advances in our understanding of the molecular mechanisms involved in hematology, these inefficient, time-consuming, and labor-intensive approaches did not permit the development of cellular or animal models, recapitulating the complexity of hematological disorders. On October 26, 2016, Drs. Ben Ebert and Chad Cowan shared their knowledge of and experience with the utilization of CRISPR for models of myeloid malignancy, disease, and novel therapeutics in an International Society for Experimental Hematology webinar titled "Utility of CRISPR/Cas9 Systems in Hematology Research." Here, we provide an overview of the topics they covered, including their insights into the novel applications of the technique and its strengths and limitations. Copyright © 2017 ISEH – Society for Hematology and Stem Cells. Published by Elsevier Inc. All rights reserved.

  11. Value of innovation in hematologic malignancies: a systematic review of published cost-effectiveness analyses.

    Saret, Cayla J; Winn, Aaron N; Shah, Gunjan; Parsons, Susan K; Lin, Pei-Jung; Cohen, Joshua T; Neumann, Peter J

    2015-03-19

    We analyzed cost-effectiveness studies related to hematologic malignancies from the Tufts Medical Center Cost-Effectiveness Analysis Registry (www.cearegistry.org), focusing on studies of innovative therapies. Studies that met inclusion criteria were categorized by 4 cancer types (chronic myeloid leukemia, chronic lymphocytic leukemia, non-Hodgkin lymphoma, and multiple myeloma) and 9 treatment agents (interferon-α, alemtuzumab, bendamustine, bortezomib, dasatinib, imatinib, lenalidomide, rituximab alone or in combination, and thalidomide). We examined study characteristics and stratified cost-effectiveness ratios by type of cancer, treatment, funder, and year of study publication. Twenty-nine studies published in the years 1996-2012 (including 44 cost-effectiveness ratios) met inclusion criteria, 22 (76%) of which were industry funded. Most ratios fell below $50,000 per quality-adjusted life-years (QALY) (73%) and $100,000/QALY (86%). Industry-funded studies (n = 22) reported a lower median ratio ($26,000/QALY) than others (n = 7; $33,000/QALY), although the difference was not statistically significant. Published data suggest that innovative treatments for hematologic malignancies may provide reasonable value for money. © 2015 by The American Society of Hematology.

  12. Reference Intervals of Hematology and Clinical Chemistry Analytes for 1-Year-Old Korean Children.

    Lee, Hye Ryun; Shin, Sue; Yoon, Jong Hyun; Roh, Eun Youn; Chang, Ju Young

    2016-09-01

    Reference intervals need to be established according to age. We established reference intervals of hematology and chemistry from community-based healthy 1-yr-old children and analyzed their iron status according to the feeding methods during the first six months after birth. A total of 887 children who received a medical check-up between 2010 and 2014 at Boramae Hospital (Seoul, Korea) were enrolled. A total of 534 children (247 boys and 287 girls) were enrolled as reference individuals after the exclusion of data obtained from children with suspected iron deficiency. Hematology and clinical chemistry analytes were measured, and the reference value of each analyte was estimated by using parametric (mean±2 SD) or nonparametric methods (2.5-97.5th percentile). Iron, total iron-binding capacity, and ferritin were measured, and transferrin saturation was calculated. As there were no differences in the mean values between boys and girls, we established the reference intervals for 1-yr-old children regardless of sex. The analysis of serum iron status according to feeding methods during the first six months revealed higher iron, ferritin, and transferrin saturation levels in children exclusively or mainly fed formula than in children exclusively or mainly fed breast milk. We established reference intervals of hematology and clinical chemistry analytes from community-based healthy children at one year of age. These reference intervals will be useful for interpreting results of medical check-ups at one year of age.

  13. Effect of Administration of Withania somnifera on Some Hematological and Immunological Profile of Broiler Chicks

    Muhammad Mushtaq*, F. R. Durrani, N. Imtiaz, Umer Sadique1, A. Hafeez, S. Akhtar2 and S. Ahmad3

    2012-01-01

    Full Text Available This study was conducted to assess the performance of broiler chickens based on some hematological and immunological profile, upon inclusion of aqueous extract of Withania somnifera (W. somnifera in their drinking water. For this purpose, 240 a-day-old broiler chicks were purchased from a local hatchery and divided into four groups i.e. WST-0, WST-I, WST-II and WST-III. Group WST-0 was kept as control, while chicks in group WST-I, WST-II and WST-III were offered in their drinking water with an extract of W. somnifera at 10, 20 and 30g/L for 35 days, starting from day 1 of age. Feed intake and body weight were recorded on regular basis and hematological and immunological profile of the birds was analyzed at the end of experiment. Administration of W. somnifera extract resulted in significantly higher feed intake and body weight of birds in all treated groups. An increase in the values of Hb, PCV and TLC was noted in the treatment groups. A non significant difference was noted in the counts of neutrophils, lymphocytes, eosinophils and monocytes in all treatment groups as compared to control. Antibodies titers against IB and IBD were significantly higher in all treatment groups as compare to the values shown by the chicks in control group. Findings of this study indicated that administration of W. somnifera extract to broiler chicks improve their feed intake, body weight gain, hematological profile and immunological status.

  14. Effects of dance therapy on the selected hematological and rheological indicators in older women.

    Filar-Mierzwa, Katarzyna; Marchewka, Anna; Bac, Aneta; Kulis, Aleksandra; Dąbrowski, Zbigniew; Teległów, Aneta

    2017-01-01

    The aim of this study was to analyze the effects of dance therapy on selected hematological and rheological indicators in older women. The study included 30 women (aged 71.8±7.4), and the control group comprised of 10 women of corresponding age. Women from the experimental group were subjected to a five-month dance therapy program (three 45-minute sessions per week); women from the control group were not involved in any regular physical activity. Blood samples from all the women were examined for hematological, rheological, and biochemical parameters prior to the study and five months thereafter. The dance therapy program was reflected by a significant improvement of erythrocyte count and hematocrit. Furthermore, the dance therapy resulted in a significant increase in the plasma viscosity, while no significant changes in glucose and fibrinogen levels were noted. Dance therapy modulates selected hematological parameters of older women; it leads to increase in erythrocyte count and hematocrit level. Dance therapy is reflected by higher plasma viscosity. Concentrations of fibrinogen and glucose are not affected by the dance therapy in older women, suggesting maintenance of homeostasis. Those findings advocate implementation of dance therapy programs in older women.

  15. Complementary and Alternative Medicine: A Clinical Study in 1,016 Hematology/Oncology Patients.

    Hierl, Marina; Pfirstinger, Jochen; Andreesen, Reinhard; Holler, Ernst; Mayer, Stephanie; Wolff, Daniel; Vogelhuber, Martin

    2017-01-01

    Surveys state a widespread use of complementary and alternative medicine (CAM) in patients with malignant diseases. CAM methods might potentially interfere with the metabolization of tumor-specific therapy. However, there is little communication about CAM use in hematology/oncology patients between patients, CAM providers, and oncologists. A self-administered questionnaire was handed out to all patients attending to the hematology/oncology outpatient clinic of Regensburg University Hospital. Subsequently, a chart review of all CAM users was performed. Questionnaires of 1,016 patients were analyzed. Of these patients, 30% used CAM, preferably vitamins and micronutrients. Main information sources for CAM methods were physicians/nonmedical practitioners and friends/relatives. CAM therapies were provided mainly by licensed physicians (29%), followed by nonmedical practitioners (14%) and the patients themselves (13%). Although 62% of the CAM users agreed that the oncologist may know about their CAM therapy, a chart entry about CAM use was found only in 41%. CAM is frequently used by hematology/oncology patients. Systematic communication about CAM is essential to avoid possible drug interactions. © 2017 S. Karger AG, Basel.

  16. Effect of feeding cottonseed meal on some hematological and serum biochemical parameters in broiler birds

    G. Thirumalaisamy

    2016-07-01

    Full Text Available Aim: The study was undertaken to find out the effect of feeding cottonseed meal (CSM on performance of hematological and serum biochemical parameters in broiler birds. Materials and Methods: A 6-week biological trial was carried out with 432-day-old Cobb 400 broiler chicks distributed to nine experimental diets with six replicates, each containing eight chicks. The experimental diets were formulated based on total amino acids (BTAA or based on digestible amino acids (BDAA with or without iron supplementation with two levels of CSM (2% and 4% and control diet based on maize – soybean. The whole blood was subjected to hematological studies. The serum samples were analyzed for protein fractions and lipid profiles. Results: The packed cell volume (PCV value, red blood cell (RBC numbers, and hemoglobin (Hb were lower in iron unsupplemented CSM BTAA or BDAA diets than the control (33.86-35.54 vs. 36.41%, 2.78-2.87 vs. 2.98 × 106/μl, and 10.30-10.70 vs. 10.88%. Supplementation of iron in CSM diets improved the PCV, RBC numbers, and Hb, and the values were comparable to the control. White blood cell numbers, mean corpuscular volume, mean corpuscular Hb (MCH, and MCH concentration values were comparable to the control. The erythrocyte osmotic fragility (EOF was poor in birds fed diets containing up to 4% CSM BTAA or CSM BDAA without iron supplementation (32.02-32.57 vs. 28.77%. Supplementation of iron improved the EOF. The serum cholesterol level did not change with or without iron supplementation. Conclusion: This study suggested that feeding of CSM BTAA or BDAA up to 4% level voiding iron supplementation lowers the hematological parameters, whereas supplementation of iron did not alter serum protein fractions and cholesterol profile; however, it had lowered some hematological parameters, which was rectified by iron supplementation.

  17. The effects of combination of Eurycoma longifolia Jack ethanolic extract and doxorubicine on hematological profile in rats given by 7,12-dimethylbenz(a)anthracene

    Nurani, L. H.; Mursyidi, A.; Widyarini, S.; Rohman, A.

    2017-11-01

    Doxorubicin (Dox) is known as anticancer drug commonly used for cancer treatment. Eurycoma longifolia Jack or Pasakbumi was reported to have chemopreventive effect. In cancer patients, there are some dysfunctions of blood parameter, therefore some hematologic tests are needed to monitor cancer patients. In this study, the effects of combination of ethanolic extract of E. longifolia Jack (EEE) and Dox on hematologic profiles were investigated in rats injected by DMBA. Rats were divided into eight groups. Group I was normal group; Group II, rats were treated with extract dose 100 mg/kgbw; Groups III, IV, V, VI, VII and VIII, rats were treated with Dox, DMBA, DMBA+Dox, DMBA+EEE, DMBA+Dox +EEE, and Dox+EEE, respectively. DMBA administration orally was conducted twice a week for 5 weeks. At 16th week of treatments, bloods were taken from orbitalis sinus for hematologicals profile (levels of Hb, erytrocyte, hematocrite, leukocyte, MCV, MCH, and differencial leucocyte count) measurements. These data were analyzed by one way ANOVA followed by LSD test. DMBA administration significantly decreased the hematological profiles compared to the normal group, except in lymphocyte level. Rats treated with extract and extract+Dox were able to increase the hematological profile compared to rats given by DMBA only. Based on these findings it can be concluded that the combination of EEE and Dox potentially increase hematological profile of rats given by DMBA.

  18. Value of innovation for hematologic malignancies.

    Monia, Marchetti

    2016-01-01

    Several novel drugs are dramatically improving both lifespan and quality-of-life of patients with blood cancers. Prolonged disease duration and increased treatment costs for hematologic malignancies impose a relevant economic burden onto healthcare services, despite the low incidence of blood cancers. Therefore, an appropriate paradigm for valuing 'innovation' is urgently required in order to refine pricing and reimbursement decisions. Cost-per-QALY-gained is still the standard metric for assessing the 'incremental' value of new drugs; however, the high number of 'comparator' therapies and the huge variety of treatment sequences make plain two-treatment comparisons sub-optimal, while multiple-treatment and multiple-sequence comparisons require complex and less-transparent decision models. A repository of standard backbones for decision models might allow benchmarking and comparability among cost-effectiveness analyses; however, an international effort is required to build it up. Deontology recommends that hematologists act in optimizing healthcare resources while preserving patient-physician alliance, but clinical practice guidelines do not support doctors in balancing cost against clinical outcomes. Decision models of chronic blood cancers unexpectedly proved that cost might be an appropriate value for innovation if treatments avoided severe toxicity and further lines of treatments, despite the eventually long duration of treatment and the competing risk of death due to comorbidity and old age. The improved transparency of decision models allows sharing of relevant structural and analytic parameters (i.e., time horizon, comparator treatments, hierarchy of end-point, assumptions, source of data, sub-group analyses) by stakeholders, physicians and patients, making health economics a noble 'translator' of values for innovation.

  19. Risk of hematological malignancies among Chernobyl liquidators

    Kesminiene, Ausrele; Evrard, Anne-Sophie; Ivanov, Viktor K.; Malakhova, Irina V.; Kurtinaitis, Juozas; Stengrevics, Aivars; Tekkel, Mare; Anspaugh, Lynn R.; Bouville, André; Chekin, Sergei; Chumak, Vadim V.; Drozdovitch, Vladimir; Gapanovich, Vladimir; Golovanov, Ivan; Hubert, Phillip; Illichev, Sergei V.; Khait, Svetlana E.; Krjuchkov, Viktor P.; Maceika, Evaldas; Maksyoutov, Marat; Mirkhaidarov, Anatoly K.; Polyakov, Semion; Shchukina, Natalia; Tenet, Vanessa; Tserakhovich, Tatyana I.; Tsykalo, Aleksandr; Tukov, Aleksandr R.; Cardis, Elisabeth

    2010-01-01

    A case-control study of hematological malignancies was conducted among Chernobyl liquidators (accident recovery workers) from Belarus, Russia and Baltic countries in order to assess the effect of low-to-medium dose protracted radiation exposures on the relative risk of these diseases. The study was nested within cohorts of liquidators who had worked in 1986–87 around the Chernobyl plant. 117 cases (69 leukemia, 34 non-Hodgkin Lymphoma (NHL) and 14 other malignancies of lymphoid and hematopoietic tissue) and 481 matched controls were included in the study. Individual dose to the bone marrow and uncertainties were estimated for each subject. The main analyses were restricted to 70 cases (40 leukemia, 20 NHL and 10 other) and their 287 matched controls with reliable information on work in the Chernobyl area. Most subjects received very low doses (median 13 mGy). For all diagnoses combined, a significantly elevated OR was seen at doses of 200 mGy and above. The Excess Relative Risk (ERR) per 100 mGy was 0.60 (90% confidence interval (CI): −0.02, 2.35). The corresponding estimate for leukemia excluding chronic lymphoid leukemia (CLL) was 0.50 (90%CI −0.38, 5.7). It is slightly higher than, but statistically compatible with, those estimated from a-bomb survivors and recent low dose-rate studies. Although sensitivity analyses showed generally similar results, we cannot rule out the possibility that biases and uncertainties could have led to over or underestimation of the risk in this study. PMID:19138033

  20. Hematologic studies of irradiated survivors in Hiroshima, Japan. Refractory anemia occurring in survivors of the atomic bombing in Nagasaki, Japan

    Yamasowa, Yoshimichi; Lange, R D; Wright, S W; Tomonaga, Masanobu; Kurasaki, Hirotami; Matsuoka, Shigeru; Matsunaga, Haruji

    1959-01-01

    This document contains 2 reports on the effects of radiation on the survivors of the atomic explosions in Hiroshima and Nagasaki. The first report is a hematologic survey conducted 33 to 44 months after the detonation of the atomic bomb in Hiroshima, Japan. The hematologic findings on a total of 824 survivors are compared with those on a control group of 1145 residents of Kure. Although statistical differences are apparent in the two groups, when one takes into account errors inherent in the hematologic methods themselves and differences in the possible incidence of parasitism and nutrition it would be unwarranted to attribute the slight changes found to radiation effect. The data presented here seem to indicate that radiation resulting from the explosion of the atomic bomb in Hiroshima, on August 6, 1945, has not significantly varied the hematologic values as analyzed in this report over a three-to four-year period. In the second report, the case histories of six Nagasaki atomic bomb survivors who developed refractory anemia are presented. Four of these individuals received undoubted radiation injury. The fact that refractory anemia may occur as a late manifestation of exposure to atomic radiation is pointed out. 15 references, 5 figures, 2 tables.

  1. Karyotype in secondary hematologic disorders after treatment for Hodgkin's disease. A study of 19 patients

    Iurlo, A.; Mecucci, C.; Van Orshoven, A.; Michaux, J.L.; Boogaerts, M.; Van den Berghe, H.

    1988-01-01

    In 19 cases of secondary hematologic disorders in patients previously treated for Hodgkin's disease, chromosome aberrations were analyzed in relation to the type of previous chemo- and/or radiotherapy, age of the patients, histopathologic features of the Hodgkin's disease at diagnosis, time interval between the treatment and the occurrence of the secondary disorder, and survival. The karyotype was of significant prognostic value when three cytogenetic groups were considered: patients with normal karyotypes; patients with aberrations of chromosome 7 as the sole anomaly; and patients with complex rearrangements and translocations. The last group showed the lowest rate of survival. Bone marrow transplantation was successful in two patients with a normal karyotype

  2. Hematological abnormalities in adult patients with Down's syndrome.

    McLean, S

    2012-02-01

    BACKGROUND: There is a paucity of data regarding hematological abnormalities in adults with Down\\'s syndrome (DS). AIMS: We aimed to characterize hematological abnormalities in adult patients with DS and determine their long-term significance. METHODS: We retrospectively studied a cohort of nine DS patients referred to the adult hematology service in our institution between May 2001 and April 2008. Data collected were: full blood count (FBC), comorbidities, investigations performed, duration of follow-up and outcome to most recent follow-up. RESULTS: Median follow-up was 26 months (9-71). Of the nine patients, two had myelodysplastic syndrome (MDS) at presentation. Of these, one progressed, with increasing marrow failure, and requiring support with transfusions and gCSF. The remaining eight patients, with a variety of hematological abnormalities including leukopenia, macrocytosis, and thrombocytopenia, had persistently abnormal FBCs. However there was no evidence of progression, and no patient has evolved to acute myeloid leukemia (AML). CONCLUSIONS: MDS is a complication of DS and may require supportive therapy. However, minor hematological abnormalities are common in adult DS patients, and may not signify underlying marrow disease.

  3. Implementing a clinical pharmacy service in hematology.

    Farias, Tatiane Fernandes; Aguiar, Karina da Silva; Rotta, Inajara; Belletti, Klezia Morais da Silva; Carlotto, Juliane

    2016-01-01

    To implement a clinical pharmacy service focused on the comprehensive review of antineoplastic drugs used in therapy of hematological diseases. An interventional study was conducted in a Brazilian tertiary teaching hospital in two different periods, with and without a clinical pharmacy service, respectively. This service consisted of an antineoplastic prescription validation (analysis of patients' characteristics, laboratory tests, compliance with the therapeutic protocol and with pharmacotechnical parameters). When problems were detected, the pharmacist intervened with the physician or another health professional responsible for the patient. Inpatients and outpatients with hematological diseases were included. We found an increased detection of drug-related problem by 106.5% after implementing the service. Comparing the two periods, an increase in patients' age (26.7 years versus 17.6 years), a predominance of outpatients (54% versus 38%), and an increase in multiple myeloma (13% versus 4%) and non-Hodgkin lymphoma (16% versus 3%) was noted. The most commonly found problems were related to dose (33% versus 25%) and cycle day (14% versus 30%). With regard to clinical impact, the majority had a significant impact (71% versus 58%), and in one patient from the second period could have been fatal. The main pharmaceutical interventions were dose adjustment (35% versus 25%) and drug withdrawal (33% versus 40%). The pharmacy service contributed to increase the detection and resolution of drug-related problems, and it was an effective method to promote the safe and rational use of antineoplastic drugs. Implementar um serviço farmacêutico clínico centrado na revisão completa dos antineoplásicos utilizados no tratamento de doenças hematológicas. Estudo intervencional conduzido em um hospital universitário terciário brasileiro em dois períodos distintos, com base na ausência e na presença do serviço farmacêutico clínico, respectivamente. O referido servi

  4. Symptomatic splenic hamartoma with renal, cutaneous, and hematological abnormalities

    Kassarjian, A.; Patenaude, Y.G.; Bernard, C.; Bell, L.

    2001-01-01

    Background. There is a rare association between splenic hamartomas and hematological abnormalities with, to our knowledge, only 24 reported cases in the English literature. Patients and methods. We report a case of a splenic hamartoma in a 14-year-old boy associated with membranoproliferative glomerulonephritis, multiple lobular capillary hemangiomas of the skin, hypertension, and anemia. Following imaging with ultrasonography, MRI, and nuclear scans, a hamartoma was suspected, but malignancy could not be excluded. The lesion was removed by partial splenectomy, and pathological examination confirmed the presence of a red pulp splenic hamartoma. Results. The renal, hematological, and dermatological abnormalities resolved following removal of the splenic hamartoma. This is the first reported case of a splenic hamartoma associated with renal, cutaneous, and hematological abnormalities and only the second reported case of a symptomatic splenic hamartoma treated by partial splenectomy. (orig.)

  5. Symptomatic splenic hamartoma with renal, cutaneous, and hematological abnormalities

    Kassarjian, A.; Patenaude, Y.G. [Dept. of Medical Imaging, Montreal Children' s Hospital, PQ (Canada); Bernard, C. [Dept. of Pathology, Montreal Children' s Hospital, PQ (Canada); Bell, L. [Dept. of Nephrology, Montreal Children' s Hospital, PQ (Canada)

    2001-02-01

    Background. There is a rare association between splenic hamartomas and hematological abnormalities with, to our knowledge, only 24 reported cases in the English literature. Patients and methods. We report a case of a splenic hamartoma in a 14-year-old boy associated with membranoproliferative glomerulonephritis, multiple lobular capillary hemangiomas of the skin, hypertension, and anemia. Following imaging with ultrasonography, MRI, and nuclear scans, a hamartoma was suspected, but malignancy could not be excluded. The lesion was removed by partial splenectomy, and pathological examination confirmed the presence of a red pulp splenic hamartoma. Results. The renal, hematological, and dermatological abnormalities resolved following removal of the splenic hamartoma. This is the first reported case of a splenic hamartoma associated with renal, cutaneous, and hematological abnormalities and only the second reported case of a symptomatic splenic hamartoma treated by partial splenectomy. (orig.)

  6. Bleeding frequency and characteristics among hematologic malignancy inpatient rehabilitation patients with severe thrombocytopenia.

    Fu, Jack B; Tennison, Jegy M; Rutzen-Lopez, Isabel M; Silver, Julie K; Morishita, Shinichiro; Dibaj, Seyedeh S; Bruera, Eduardo

    2018-03-28

    To identify the frequency and characteristics of bleeding complications during acute inpatient rehabilitation of hematologic malignancy patients with severe thrombocytopenia. Retrospective descriptive analysis. Comprehensive cancer center acute inpatient rehabilitation unit. Consecutive hematologic malignancy patients with a platelet count of less than or equal to 20,000/microliter (μL) on the day of acute inpatient rehabilitation admission from 1/1/2005 through 8/31/2016. Medical records were retrospectively analyzed for demographic, laboratory, and medical data. Patients were rehabilitated using the institutional exercise guidelines for thrombocytopenic patients. Bleeding events noted in the medical record. Out of 135 acute inpatient rehabilitation admissions, 133 unique patients were analyzed with a total of 851 inpatient rehabilitation days. The mean platelet count was 14,000/μL on the day of admission and 22,000/μL over the course of the rehabilitation admission. There were 252 days of inpatient rehabilitation where patients had less than 10,000/μL platelets. A total of 97 bleeding events were documented in 77/135 (57%) admissions. Of the 97 bleeding events, 72 (74%), 14 (14%), and 11 (11%) were considered to be of low, medium, and high severity, respectively. There were 4/97 (4%) bleeding events that were highly likely attributable to physical activity but only 1/4 was considered high severity. Bleeding rates were .09, .08, .17, and .37 for > 20,000, 15-20,000, 10-15,000, and rehabilitation in severely thrombocytopenic hematologic cancer patients. Bleeding rates increased with lower platelet counts. However, using the exercise guidelines for severely thrombocytopenic patients, the risk of severe exercise-related bleeding events was low.

  7. STATUS SEROLOGIS TIDAK MEMPENGARUHI PROFIL HEMATOLOGI ANAK TERINFEKSI VIRUS DENGUE

    Safari Wahyu Jatmiko

    2017-06-01

    Full Text Available Antibodi anti dengue bersifat autoantibodi yang bisa merusak self antigen. Respon imun humoral terhadap DENV adalah terbentuknya IgM dan IgG yang spesifik terhadap sub tipe DENV penyebab. Jika IgG dan IgM anti degue bersifat autoantibodi maka secara teoritis pasien dengan status serologis IgM (+ dan IgG + akan mempunyai profil hematologi yang lebih buruk dari pada pasien dengan IgG (+.Penelitian ini bertjuan untuk mengetahui perbedaan profil hematologi menurut status serologi pada anak terinfeksi virus dengue. Penelitian menggunakan desian analitik dengan pendekatan cross sectional. Data diambil dari pasien anak di RSUD Surakarta dari bulan September 2016 – Januari 2017. Kriteria pasien yang diikutkan dalam penelitian adalah semua pasien anak dengan usia kurang dari 14 tahun dan memenuhi kriteria infeksi virus dengue menurut WHO 2009. Pasien dengan riwayat kelainan hematologi dan pasien dengan riwayat immunocompremised dikeluarkan dari penelitian.Hasil penelitian ditemukan 65 pasien dengan IVD yang memenuhi kriteria.Tujuh belas pasien dengan IgM dan IgG positif sedangkan sisanya hanya IgG positif Hasil penelitian perbedaan profil hematologi jumlah leukosit, trombosit, hematokrit, dan hemoglobin berdasarkan status IgM (+ IgG (+ dengan IgG (+ didapatkan nilai p masing-masing 0.833, 0,865, 0,137, 0,086, dan 0,223. Dapat disimpilkan bahwa tidak terdapat perbedaan profil hematologi antara pasien dengan IgM (+ IgG (+ dengan pasien IgG (+.   Kata Kunci: infeksi virus dengue, antibodi anti dengue, autoantibodi, profil hematologi.

  8. Computerized tomography in the study of intracranial complications in hematology

    Gastaut, J.L.; Gastaut, J.A.

    1979-01-01

    CT was used to examine 100 patients with various hematologic disorders. It was generally in patients with clinical signs of encephalic alteration (68% of the cases) that we demonstrated lesions. In several cases, the lesions were detected by CT, whereas common neurological investigational methods remained negative. The most interesting findings were in acute leukemias (leucoblastic infiltrations, cerebral hemorrhages and infarctions, and iatrogenic morphologic modifications) and in Hodgkin diseases (intracranial localizations). CT permits a more complete neurologic work-up for patients with hematologic disorders and provides a better knowledge of the frequency and varieties of intracranial complications. (orig.) 891 MG/orig. 892 MB [de

  9. Resources for Hematology On and Off the Web.

    Sebald-Kinder, Shirley; Petty, Janet L

    2017-09-01

    Searching the literature can be challenging because of the large volume of information. It can be time consuming to locate and determine what evidence will provide the best health outcomes for patients. In addition, locating hematology information for patients and family members is one of the most challenging of all health care topics. Hematology can be technical and difficult for most people to understand, especially for those with little or no science background and poor reading skills. This article provides guidance on how and where to locate information to address the needs of both clinicians and patients. Copyright © 2017 Elsevier Inc. All rights reserved.

  10. High prevalence of malnutrition among patients with solid non-hematological tumors as found by using skinfold and circumference measurements

    Adriana Garófolo

    Full Text Available CONTEXT AND OBJECTIVE: Malnutrition in cancer patients has many causes. Nutritional status is usually assessed from weight/height indices. These present limitations for the nutritional assessment of cancer patients: their weights include tumor mass, and lean mass changes are not reflected in weight/height indices. The objective was to evaluate differences between two anthropometric methods and compare deficits, in non-hematological tumor patients and hematological disease patients. DESIGN AND SETTING: Cross-sectional study at Instituto de Oncologia Pediátrica, Universidade Federal de São Paulo. METHODS: Children and adolescents were evaluated between March 1998 and January 2000. Traditional anthropometric measurements were obtained in the first month of treatment (induction therapy, by weight-for-height (W/H using z-scores index for children and body mass index (BMI for adolescents. Body composition evaluations consisted of specific anthropometric measurements: triceps skinfold thickness (TSFT, mid-upper arm circumference (MUAC and arm muscle circumference (AMC. Data were analyzed to compare nutritional assessment methods for diagnosing malnutrition prevalence. The chi-squared test was used for comparative analyses between tumor patients and hematological disease patients. RESULTS: Analysis was done on 127 patients with complete data. Higher percentages of deficits were found among tumor patients, by W/H z-scores or BMI and by MUAC and AMC. Higher percentages of deficits were shown by TSFT (40.2% and MUAC (35.4% than by W/H z-scores or BMI (18.9%. CONCLUSION: Non-hematological tumor patients presented higher malnutrition prevalence than did hematological disease patients. Body composition measurements by TSFT and MUAC detected more patients with malnutrition than did W/H or BMI.

  11. Protective role of Carica papaya (Linn.) in electron beam radiation induced hematological and cytogenetic damages in Swiss albino mice

    Yogish Somayaji, T.; Suchetha Kumari, N.

    2014-01-01

    Carica papaya (Linn.) is known to possess various biomedical applications. It has remarkable antioxidant properties. The main objective of the study was to evaluate the leaf extracts of Carica papaya (Linn.) on hematologic and cytogenetic changes occurring due to irradiation of mice to sub-lethal doses of Electron Beam Radiation (EBR). Analysis of hematological changes occurring due to irradiation of mice to sub-lethal doses of EBR, and the effects of Carica papaya (Linn.) extract on the same. The Assessment of hematopoietic stress by spleen colony forming unit and spleen body weight index. The analysis of cell proliferation and immunomodulation with response to the effects of Carica papaya (Linn.) extract by estimation of IL-6. The estimation of serum total antioxidants, lipid peroxidation and analyzing the activities of enzymes like SOD, ALP, and AST. Male Swiss albino mice were fed orally with papaya aqueous leaf extract for 15 days. They were irradiated with a whole body dose of 6 Gy Electron Beam radiation. The mice were dissected for liver, kidney, bone marrow, spleen and brain. The hematological studies were done using blood cell count in an automated cell counter. The biochemical estimations like urea, creatinine, SGOT, SGPT, Total Protein, Albumin, Bilirubin were done using the serum and homogenates. The total antioxidant capacity, the antioxidant enzymes were estimated. The Interleukin-6 levels were estimated in serum to assess immune modulation. The results show a decrease in the hematological parameters in radiated animals. The papaya treated groups have shown modulation in the hematological parameters. The extract has also reduced the suppression of the bone marrow induced by radiation. The radiation induced liver damage is also reduced in papaya treated groups. The aqueous extract of Carica papaya (Linn.) has shown protective effects in electron beam radiation induced tissue damages in Swiss Albino mice (author)

  12. Diurnal variation of hematology parameters in healthy young males: the Bispebjerg study of diurnal variations

    Sennels, Henriette P; Jørgensen, Henrik L; Hansen, Anne-Louise S

    2011-01-01

    To evaluate the influence of time of day on the circulating concentrations of 21 hematology parameters.......To evaluate the influence of time of day on the circulating concentrations of 21 hematology parameters....

  13. The effect of lead poisoning on hematologic and biochemical values in trumpeter swans and Canada geese.

    Katavolos, P; Staempfli, S; Sears, W; Gancz, A Y; Smith, D A; Bienzle, D

    2007-12-01

    Lead is a persistent contaminant in the environment, and waterfowl are susceptible to lead toxicity from ingestion of lead pellets and fishing weights. Lead affects numerous physiologic processes through inhibition of enzyme activity and protein function, but its effects on commonly assessed avian blood values are incompletely understood. Our aim was to evaluate hematologic and biochemical changes associated with blood lead concentrations in trumpeter swans and Canada geese. Data for CBCs, plasma biochemical profiles (total protein, albumin, glucose, cholesterol, total bilirubin, calcium, phosphorus, gamma-glutamyltransferase [GGT], aspartate aminotransferase, lactate dehydrogenase, glutamate dehydrogenase, creatine kinase, amylase, and lipase), and whole blood lead concentrations were retrospectively analyzed for 69 trumpeter swans and 52 Canada geese. Laboratory data obtained prospectively from an additional 20 trumpeter swans also were included. RBC morphology was semiquantitated in blood smears from 70 of the birds. Data were analyzed initially by ANOVA and covariance. A statistical model then was constructed to determine the relationship between each parameter and lead concentration. In both avian species, PCV, hemoglobin concentration, and MCHC decreased significantly (P < .05) with increasing blood lead concentration. Uric acid concentration and GGT activity were increased in trumpeter swans and phosphorus concentration was decreased in Canada geese in association with high blood lead concentration (P < .05). Lead toxicosis induced significant changes in the values of commonly measured hematologic parameters in waterfowl. These changes may be useful indicators of severe lead intoxication during routine laboratory assessment. Changes in clinical chemistry values, although statistically significant, were too inconsistent to serve as indicators of lead toxicosis.

  14. The Effect of Alcohol Intoxications on Hematological Parameters of ...

    Due to the accessibility of alcohol, people around the world become readily intoxicated with it and in turn, it produces protease devastating effects in the human system. This study investigates the hematological effects of alcohol in albino rats grouped into three (A, B and C). Group A and B served as test while C served as ...

  15. Kytococcus schroeteri Pneumonia in Two Patients with a Hematological Malignancy

    Hodiamont, C. J.; Huisman, C.; Spanjaard, L.; van Ketel, R. J.

    2010-01-01

    Neutropenic patients are susceptible to infections with usually harmless microorganisms. We report two cases of severe pneumonia in hematological patients due to Kytococcus schroeteri, a saprophyte of the human skin. When blood cultures or respiratory specimens yield micrococcus-like colonies,

  16. Evaluation of febrile neutropenic patients hospitalized in a hematology clinic

    Mücahit Görük

    2015-12-01

    Conclusions: Febrile neutropenia is still a problem in patients with hematological malignancies. The documentation of the flora and detection of causative agents of infections in each unit would help to decide appropriate empirical therapy. Infection control procedures should be applied for preventing infections and transmissions.

  17. Aspects of the Hematology and Serum Biochemistry of Sahel and ...

    This study was conducted to investigate effects of year, age, season and breeds on aspects of the hematology and serum biochemical indices of Sahel and Sokoto red bucks in Mubi, Adamawa state, Nigeria. Blood and serum samples were used to determine PCV, Hb, RBC and WBC, and while serum protein (BSP) and ...

  18. Influence of Wallow on Some Hematological Parameters and Serum ...

    A study was conducted to determine the influence of wallow on some hematological and serum enzymes of growing pigs. Six pre-pubertal pigs of average age 2months were randomly assigned to two treatment groups, comprising of Wallow (A) and Non-Wallow facilities (B) in a Completely Randomized Design(CRD).

  19. Hematological and male hormonal profile of two cattle breeds ...

    Baseline data on the hematology of White Fulani and Muturu breeds of Cattle have been reported. However, very few documented studies have been carried out with regards to the reproductive hormonal profile of these breeds. Satisfactory reproductive performance is important to effective management and production as a ...

  20. Hematological clozapine monitoring with a point-of-care device

    Nielsen, Jimmi; Thode, Dorrit; Stenager, Elsebeth

    2012-01-01

    for several reasons, perhaps most importantly because of the mandatory hematological monitoring. The Chempaq Express Blood Counter (Chempaq XBC) is a point-of-care device providing counts of white blood cells (WBC) and granulocytes based on a capillary blood sampling. A randomized cross-over trial design...