Sample records for helvetica chemica acta

  1. Acta Structilia

    Acta Structilia Journal is a South African accredited national journal for ... building economy, engineering and property or community development. ... critical analysis of pertinent risks in the Zambian construction industry · EMAIL FREE FULL TEXT ... Stakeholders' perception of critical success factors for sustainable facilities ...

  2. Acta Theologica: Submissions

    Acta Theologica. ... Manuscripts should be between 4000 and 7000 words. ... Three to four key words in both English and Afrikaans should be provided at the end of the article. ... Use capital letters in the title only where absolutely necessary.

  3. Helvetica, the Film and the Face in Context

    Winkler, Dietmar R.


    Little historic context is generally provided regarding design phenomena; ideas, names, events and relationships are disregarded in design's typical superficial coverage; it is as though design exists in a vacuum. This paper seeks to put Helvetica, the face, the font and the movie into context by exploring its relationship to Swiss Design…

  4. ACTA - Pro et contra

    Ellebæk, Kristoffer; Stilling, Christian; Durst-Andersen, Sara S.; Vilsbøll, Signe Mai K.


    Resumé Projektrapporten har til formål at undersøge etiske problemstillinger, der opstår ved indgåelse ved en eventuel handelsaftale som ACTA (Anti-Counterfeiting Trade Agreement). Handelsaftalen er et forsøg på at sikre øgede muligheder for håndhævelse af den intellektuelle ejendomsret på tværs af landegrænser. En del af ACTA aftalen er møntet på begrænsning af piratkopiering over internettet. Ved at redegøre for den meget udbredte peer-to-peer-fildelingsteknologi (p2p) og dennes egenskaber,...



    Acta Optica Sinica is a scientific periodical on optics,sponsored by Chinese Optical Society, jointly undertaken by Shanghai Institute of Optics and Fine Mechanics,Changchun Institute of Optics, Fine Mechanics and Physics,the Chinese Academy of Sciences, monthly,first published in 1981. The chief editor is Professor Xu Zhizhan, Academician of the Chinese Academy of Sciences. Now Acta Optica Sinica is a source periodical of the following international index periodicals: SA,CA,EI and PЖ.

  6. Detection and identification of Anaplasma phagocytophilum, Borrelia burgdorferi, and Rickettsia helvetica in Danish Ixodes ricinus ticks

    Skarphédinsson, Sigurdur; Lyholm, Birgitte Fjendbo; Ljungberg, Marianne


    % of adult ticks. The difference in prevalence between Anaplasma and Borrelia in adult ticks supports the idea that their maintenance cycles in nature may be different. Ticks were also infected with Rickettsia helvetica. Our study indicates that A. phagocytophilum prevalence in ticks in Denmark is as high...

  7. Ixodes ricinus ticks are reservoir hosts for Rickettsia helvetica and potentially carry flea-borne Rickettsia species

    Gaasenbeek Cor


    Full Text Available Abstract Background Hard ticks have been identified as important vectors of rickettsiae causing the spotted fever syndrome. Tick-borne rickettsiae are considered to be emerging, but only limited data are available about their presence in Western Europe, their natural life cycle and their reservoir hosts. Ixodes ricinus, the most prevalent tick species, were collected and tested from different vegetation types and from potential reservoir hosts. In one biotope area, the annual and seasonal variability of rickettsiae infections of the different tick stages were determined for 9 years. Results The DNA of the human pathogen R. conorii as well as R. helvetica, R. sp. IRS and R. bellii-like were found. Unexpectedly, the DNA of the highly pathogenic R. typhi and R. prowazekii and 4 other uncharacterized Rickettsia spp. related to the typhus group were also detected in I. ricinus. The presence of R. helvetica in fleas isolated from small rodents supported our hypothesis that cross-infection can occur under natural conditions, since R. typhi/prowazekii and R. helvetica as well as their vectors share rodents as reservoir hosts. In one biotope, the infection rate with R. helvetica was ~66% for 9 years, and was comparable between larvae, nymphs, and adults. Larvae caught by flagging generally have not yet taken a blood meal from a vertebrate host. The simplest explanation for the comparable prevalence of R. helvetica between the defined tick stages is, that R. helvetica is vertically transmitted through the next generation with high efficiency. The DNA of R. helvetica was also present in whole blood from mice, deer and wild boar. Conclusion Besides R. helvetica, unexpected rickettsiae are found in I. ricinus ticks. We propose that I. ricinus is a major reservoir host for R. helvetica, and that vertebrate hosts play important roles in the further geographical dispersion of rickettsiae.

  8. Eunuchs in the Bible | Retief | Acta Theologica

    Acta Theologica. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 26, No 2 (2006) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if ...

  9. Hippocrates: facts and fiction | Retief | Acta Theologica

    Acta Theologica. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 26, No 2 (2006) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if ...

  10. In vitro studies of Rickettsia-host cell interactions: Confocal laser scanning microscopy of Rickettsia helvetica-infected eukaryotic cell lines.

    Speck, Stephanie; Kern, Tanja; Aistleitner, Karin; Dilcher, Meik; Dobler, Gerhard; Essbauer, Sandra


    Rickettsia (R.) helvetica is the most prevalent rickettsia found in Ixodes ricinus ticks in Germany. Several studies reported antibodies against R. helvetica up to 12.5% in humans investigated, however, fulminant clinical cases are rare indicating a rather low pathogenicity compared to other rickettsiae. We investigated growth characteristics of R. helvetica isolate AS819 in two different eukaryotic cell lines with focus on ultra-structural changes of host cells during infection determined by confocal laser scanning microscopy. Further investigations included partially sequencing of rickA, sca4 and sca2 genes, which have been reported to encode proteins involved in cell-to-cell spread and virulence in some rickettsiae. R. helvetica grew constantly but slowly in both cell lines used. Confocal laser scanning microscopy revealed that the dissemination of R. helvetica AS819 in both cell lines was rather mediated by cell break-down and bacterial release than cell-to-cell spread. The cytoskeleton of both investigated eukaryotic cell lines was not altered. R. helvetica possesses rickA, but its expression is not sufficient to promote actin-based motility as demonstrated by confocal laser scanning microscopy. Hypothetical Sca2 and Sca4 proteins were deduced from nucleotide gene sequences but the predicted amino acid sequences were disrupted or truncated compared to other rickettsiae most likely resulting in non-functional proteins. Taken together, these results might give a first hint to the underlying causes of the reduced virulence and pathogenicity of R. helvetica.

  11. Cumulative indices for Spectrochima Acta, Part A and Spectrochimica Acta, Part B

    Scheeline, A.; Williams, B.; Williksen, E.; Jeffrey Steinfeld,; McEnroe, B.


    This article is an electronic publication in Spectrochimica Acta Electronica (SAE), a section of Spectrochimica Acta, Part B (SAB). The hardcopy text is accompanied by an electronic archive, stored on the SAE homepage at The archive contains data, index and program files. The main article discusses the bibliographical purpose of the program and data files. A collective index for Spectrochimica Acta for volumes since it was split into Parts A and B, and continuing through 1991 for SAA and 1997 for SAB, is presented in DBF format, along with rudimentary data entry and access software. (Copyright (c) 1998 Elsevier Science B.V., Amsterdam. All rights reserved.)

  12. [The thirty years of Acta Genetica Sinica].

    Li, Shao-Wu; Zhou, Su; Xue, Yong-Biao; Zhu, Li-Huang


    Acta Genetica Sinica (AGS) is sponsored by the Genetics Society of China and the Institute of Genetics and Developmental Biology of Chinese Academy of Sciences, and is published by Science Press. The journal is a leading national academic periodical and one of the Chinese key periodicals of natural sciences. Currently, AGS is being indexed by several well-known domestic and international indexing systems, such as the American Chemical Digest (CA), BIOSIS database, Biological Digest (BA), Medical Index and Russian Digest (P [symbol: see text]). Papers in the areas of genetics, developmental biology, cell molecular biology and evolution are regularly published by AGS.

  13. Detection of Rickettsia helvetica and Candidatus R. tarasevichiae DNA in Ixodes persulcatus ticks collected in Northeastern European Russia (Komi Republic).

    Kartashov, Mikhail Yu; Glushkova, Ludmila I; Mikryukova, Tamara P; Korabelnikov, Igor V; Egorova, Yulia I; Tupota, Natalia L; Protopopova, Elena V; Konovalova, Svetlana N; Ternovoi, Vladimir A; Loktev, Valery B


    The number of tick-borne infections in the northern European regions of Russia has increased considerably in the last years. In the present study, 676 unfed adult Ixodes persulcatus ticks were collected in the Komi Republic from 2011 to 2013 to study tick-borne rickettsioses. Rickettsia spp. DNA was detected by PCR in 51 (7.6%) ticks. The nucleotide sequence analysis of gltA fragments (765bp) from 51 ticks indicated that 60.8% and 39.2% of the ticks were infected with Rickettsia helvetica and Candidatus R. tarasevichiae, respectively. The gltA fragments showed 100% identity with those of Candidatus R. tarasevichiae previously discovered in Siberia and China, whereas R. helvetica showed 99.9% sequence identity with European isolates. The ompB had 8 nucleotide substitutions, 6 of which resulted in amino acid substitutions. In the sca9 gene, 3 nucleotide substitutions were detected, and only one resulted in amino acid substitution. The smpA, ompW, and β-lactamase genes of R. helvetica also showed a high level of sequence identity. Copyright © 2017 Elsevier GmbH. All rights reserved.

  14. Acta Unitatis Fratrum. Ediční projekt

    Just, Jiří


    Roč. 29, č. 2 (2014), s. 451-462 ISSN 0231-7494 Institutional support: RVO:67985963 Keywords : The Bohemian Brethren * protestant historiography * manuscript sources * regesta edition * Acta Unitatis Fratrum Subject RIV: AB - History

  15. Detection of Rickettsia hoogstraalii, Rickettsia helvetica, Rickettsia massiliae, Rickettsia slovaca and Rickettsia aeschlimannii in ticks from Sardinia, Italy.

    Chisu, Valentina; Leulmi, Hamza; Masala, Giovanna; Piredda, Mariano; Foxi, Cipriano; Parola, Philippe


    Tick-borne diseases represent a large proportion of infectious diseases that have become a world health concern. The presence of Rickettsia spp. was evaluated by standard PCR and sequencing in 123 ticks collected from several mammals and vegetation in Sardinia, Italy. This study provides the first evidence of the presence of Rickettsia hoogstralii in Haemaphysalis punctata and Haemaphysalis sulcata ticks from mouflon and Rickettsia helvetica in Ixodes festai ticks from hedgehog. In addition, Rickettsia massiliae, Rickettsia slovaca and Rickettsia aeschlimannii were detected in Rhipicephalus sanguineus, Dermacentor marginatus and Hyalomma marginatum marginatum ticks from foxes, swine, wild boars, and mouflon. The data presented here increase our knowledge of tick-borne diseases in Sardinia and provide a useful contribution toward understanding their epidemiology. Copyright © 2016 Elsevier GmbH. All rights reserved.

  16. Detection of Rickettsia helvetica in Ixodes ricinus infesting wild and domestic animals and in a botfly larva (Cephenemyia stimulator) infesting roe deer in Germany.

    Scheid, Patrick; Speck, Stephanie; Schwarzenberger, Rafael; Litzinger, Mark; Balczun, Carsten; Dobler, Gerhard


    Ixodes ricinus is a well-known vector of different human pathogens including Rickettsia helvetica. The role of wild mammals in the distribution and probable maintenance of Rickettsia in nature is still to be determined. We therefore investigated various parasites from different wild mammals as well as companion animals for the presence of Rickettsia. A total of 606 I. ricinus, 38 Cephenemyia stimulator (botfly larvae), one Dermacentor reticulatus, 24 Haematopinus suis (hog lice) and 30 Lipoptena cervi (deer flies) were collected from free-ranging animals during seasonal hunting, and from companion animals. Sample sites included hunting leases at three main sampling areas and five additional areas in West and Central Germany. All collected parasites were screened for Rickettsia spp. and I. ricinus were investigated for tick-borne encephalitis virus (TBEV) in addition. While no TBEV was detected, the minimum infection rate (MIR) of I. ricinus with Rickettsia was 4.1% referring to all sampling sites and up to 6.9% at the main sampling site in Koblenz area. Sequencing of a fragment of the ompB gene identified R. helvetica. Approximately one third (29.5%) of the animals carried Rickettsia-positive ticks and the MIR in ticks infesting wild mammals ranged from 4.1% (roe deer) to 9.5%. These data affirm the widespread distribution of R. helvetica in Germany. One botfly larva from roe deer also harboured R. helvetica. Botfly larvae are obligate parasites of the nasal cavity, pharynx and throat of cervids and feed on cell fragments and blood. Based on this one might hypothesise that R. helvetica likely induces rickettsemia in cervids thus possibly contributing to maintenance and distribution of this rickettsia in the field. Copyright © 2016 Elsevier GmbH. All rights reserved.

  17. Elsevier/Spectrochimica Acta atomic spectroscopy award 2015

    Omenetto, Nicolo; de Loos-Vollebregt, Margaretha


    This is to announce the 2015 Elsevier/Spectrochimica Acta award, the annual award honoring the most significant article(s) published in a volume. Elsevier makes this award on behalf of Spectrochimica Acta, Part B, to encourage the publication of top articles in this journal. All papers published during one year are considered for this award and the Editorial Advisory Board and the Guest Editor(s) of the special issue(s) are responsible for the selection. The award consists of a monetary prize of 1000 together with a presentation certificate.

  18. Elsevier/Spectrochimica Acta Atomic Spectroscopy Award 2014

    Omenetto, Nicolo'; de Loos, Greet


    This is to announce the 2014 Elsevier/Spectrochimica Acta Award, the annual award honoring the most significant article(s) published in a volume. Elsevier makes this award on behalf of Spectrochimica Acta, Part B, to encourage the publication of top articles in this journal. All papers published during one year are considered for this award and the Editorial Advisory Board and the Guest Editor(s) of the special issue(s) are responsible for the selection. The award consists of a monetary prize of 1000 together with a presentation certificate.

  19. Methylopila helvetica sp. nov. and Methylobacterium dichloromethanicum sp. nov.--novel aerobic facultatively methylotrophic bacteria utilizing dichloromethane.

    Doronina, N V; Trotsenko, Y A; Tourova, T P; Kuznetsov, B B; Leisinger, T


    Eight strains of Gram-negative, aerobic, asporogenous, neutrophilic, mesophilic, facultatively methylotrophic bacteria are taxonomically described. These icl- serine pathway methylobacteria utilize dichloromethane, methanol and methylamine as well as a variety of polycarbon compounds as the carbon and energy source. The major cellular fatty acids of the non-pigmented strains DM1, DM3, and DM5 to DM9 are C18:1, C16:0, C18:0, Ccy19:0 and that of the pink-pigmented strain DM4 is C18:1. The main quinone of all the strains is Q-10. The non-pigmented strains have similar phenotypic properties and a high level of DNA-DNA relatedness (81-98%) as determined by hybridization. All strains belong to the alpha-subgroup of the alpha-Proteobacteria. 16S rDNA sequence analysis led to the classification of these dichloromethane-utilizers in the genus Methylopila as a new species - Methylopila helvetica sp.nov. with the type strain DM9 (=VKM B-2189). The pink-pigmented strain DM4 belongs to the genus Methylobacterium but differs from the known members of this genus by some phenotypic properties, DNA-DNA relatedness (14-57%) and 16S rDNA sequence. Strain DM4 is named Methylobacterium dichloromethanicum sp. nov. (VKM B-2191 = DSMZ 6343).

  20. The language ecology of a new Afrikaans Bible | Ponelis | Acta ...

    Acta Theologica. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 22, No 1 (2002) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if ...

  1. A new framework for Bible translation | Wilt | Acta Theologica

    Acta Theologica. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 22, No 1 (2002) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if ...

  2. Advertising in Actas Dermosifiliográficas, 1909-1939.

    Díaz-Díaz, R M


    We review advertisements published in the journal Actas Dermosifiliográficas between 1909 and 1939. Treatments for sexually transmitted diseases were advertised with particular frequency, and they offer a case in point that exemplifies the close relationship between the pharmaceutical industry and medical journals. Copyright © 2012 Elsevier España, S.L. and AEDV. All rights reserved.

  3. The death of Alexander the Great | Retief | Acta Theologica

    Acta Theologica. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 26, No 2 (2006) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if ...

  4. Snake and staff symbolism in healing | Retief | Acta Theologica

    Acta Theologica. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 26, No 2 (2006) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if ...

  5. Assessment of wear facets produced by the ACTA wear machine

    Benetti, Ana R; Larsen, Liselotte; Dowling, Adam H


    . The mean wear depth was measured using the traditionally employed 2D and compared with the 3D profilometric (digital) techniques. Data were submitted to analyses of variance, Tukey's post hoc tests and Independent Samples Student's t-tests (where appropriate) at p...OBJECTIVE: To investigate the use of a three-dimensional (3D) digital scanning method in determining the accuracy of the wear performance parameters of resin-based composites (RBCs) determined using a two-dimensional (2D) analogue methodology following in-vitro testing in an Academisch Centrum...... for Tandheelkunde Amsterdam (ACTA) wear machine. METHODS: Specimens compatible with the compartments of the ACTA wear machine specimen wheel (n=10) were prepared from one commercial and four experimental RBCs. The RBC specimens were rotated against an antagonist wheel in a food-like slurry for 220,000 wear cycles...

  6. Prevalence of infection with Rickettsia helvetica in Ixodes ricinus ticks feeding on non-rickettsiemic rodent hosts in sylvatic habitats of west-central Poland.

    Biernat, Beata; Stańczak, Joanna; Michalik, Jerzy; Sikora, Bożena; Wierzbicka, Anna


    Ixodes ricinus is the most prevalent and widely distributed tick species in European countries and plays a principal role in transmission of a wide range of microbial pathogens. It is also a main vector and reservoir of Rickettsia spp. of the spotted fever group with the infection level ranging in Poland from 1.3% to 11.4%. Nevertheless, little research has been conducted so far to identify reservoir hosts for these pathogens. A survey was undertaken to investigate the presence of Rickettsia spp. in wild small rodents and detached I. ricinus. Rodents, Apodemus flavicollis mice and Myodes glareolus voles were captured in typically sylvatic habitats of west-central Poland. Blood samples and collected ticks were analyzed by conventional, semi-nested and nested PCRs. Rickettsial species were determined by sequence analysis of obtained fragments of gltA and 16S rRNA genes. A total of 2339 immature I. ricinus (mostly larvae) were collected from 158 animals. Proportion of hosts carrying ticks was 84%, being higher for A. flavicollis than for M. glareolus. Rickettsia helvetica, the only species identified, was detected in 8% of 12 nymphs and in at least 10.7% (MIR) of 804 larvae investigated. Prevalence of infected ticks on both rodent species was comparable (10.8 vs. 9%). None of blood samples tested was positive for Rickettsia spp. The results showed that in sylvatic habitats the level of infestation with larval I. ricinus was higher in A. flavicollis mice in comparison with M. glareolus voles. They show that R. helvetica frequently occurred in ticks feeding on rodents. Positive immature ticks were collected from non-rickettsiemic hosts what might suggest a vertical route of their infection (transovarial and/or transstadial) or a very short-lasting rickettsiemia in rodents. A natural vertebrate reservoir host for R. helvetica remains to be determined. Copyright © 2015 Elsevier GmbH. All rights reserved.

  7. Tempus Actas – B 3 em Saúde Coletiva

    Ana Valéria Machado MENDONCA


    Full Text Available Parece que foi ontem, quando lançamos em 2007, o volume 1, número 1 da Revista Tempus Actas em Saúde Coletiva, sob a coordenação da Unidade de Tecnologias da Informação e da Comunicação em Saúde do Núcleo de Estudos em Saúde Pública da Universidade de Brasília. Hoje, passados oito anos, a jovem revista científica, nascida no Centro-Oeste do país, tem ocupado cada vez mais espaços de reconhecimento no Brasil e no mundo, graças ao trabalho hercúleo de sua equipe de colaboradores(as, por sua disciplina e atenção aos novos tempos da comunicação científica que regem as produções de elevado rigor científico.

  8. Actas de las Conferencias Sanitarias Internacionales (1851-1938.

    Juan B. Mateos Jiménez


    Full Text Available En este breve trabajo se pretende traer a la memoria el recuerdo de las «Conferencias Sanitarias Internacionales» que, en intervalos casi regulares, se celebraron desde 1851 hasta 1938, consistiendo en una serie de reuniones en las que participaron los más importantes sanitarios, higienistas y científicos de cada época, así como los embajadores correspondientes de los más importantes países, intentando unos acuerdos que fuesen conformes para todas las naciones y que evitasen la llegada y extensión de las enfermedades pestilenciales. Esta labor resultaba harto difícil en aquellos tiempos, dado que los participantes se encontraban divididos en dos grandes y potentes grupos: los contagionistas (partidarios de los cordones sanitarios, cuarentenas y lazaretos y los miasmáticos o anticontagionistas (que rechazaban estas medidas y defendían el pleno saneamiento: individual, ambiental y general. Los descubrimientos bacteriológicos que por entonces se fueron produciendo, facilitaron los caminos para un mejor entendimiento entre los participantes en las Conferencias. En este breve trabajo se ofrece un mínimo resumen del contenido de cada una de las mismas. Hay que destacar que estas Conferencias fueron el origen de la Organización Mundial de la Salud. Se mencionan algunas de las dificultades encontradas para conseguir las fotocopias de los textos de las 14 Actas de las Conferencias. Hasta ahora solamente existían en el mundo dos colecciones completas (originales y fotocopias una en la sede de la OMS en Ginebra y otra en la Biblioteca Nacional de Medicina en Bethesda, Md. (USA. Ahora también existen en España, en el Instituto de Salud Carlos III.

  9. Acta informatica medica is indexed in pubmed and archived in pubmed central.

    Masic, Izet


    Acta Informatica Medica journal has been accepted for archiving in PubMed Central from 2011 onward. The journal started in 1993 as the official journal of the Society for Medical Informatics of Bosnia and Herzegovina. During the last 3 years, Acta Informatica Medica has een included in almost all prestigious online databases, including PubMed, Scopus and EMBASE. The 20th volume of the journal is fully international, with papers from 18 countries.

  10. Congenital mydriasis and prune belly syndrome in a child with an ACTA2 mutation.

    Brodsky, Michael C; Turan, Kadriye Erkan; Khanna, Cheryl L; Patton, Alice; Kirmani, Salman


    We report the association of congenital mydriasis with prune belly syndrome and cerebrovascular anomalies in a 9-year-old boy who was found to have an ACTA2 mutation. This case illustrates the spectrum of systemic malformations that are attributable to mutations in ACTA2 and expands the spectrum of cerebrovascular anomalies that are now known to accompany congenital mydriasis. Copyright © 2014 American Association for Pediatric Ophthalmology and Strabismus. Published by Elsevier Inc. All rights reserved.

  11. Beitraege zur Astronomiegeschichte, Band 5 (Acta Historica Astronomiae Vol. 18)

    Duerbeck, H. W.; Dick, W. R.; Hamel, J.


    The 18th volume of the Acta Historica Astronomiae is at the same time the sixth collection of essays on the history of astronomy ("Beitræge zur Astronomiegeschichte, Band 6"), edited by the historians of astronomy W.R. Dick (Potsdam) and J. Hamel (Berlin). Besides a few short notices and book reviews, the book contains eight major articles, which deal with astronomical topics covering the time from the 16th to the 19th centuries. The first article by Michael Weichenhan (Berlin) deals with "the invention of the disk-shaped earth: a chapter of Copernican apologetics". The author shows that the concept of a "disc-shaped Earth" was by no means widespread in the middle ages, but restricted to the father of the church Lactantius and some adherents. Nevertheless, it was used by adherents of Copernicus to show the absurd consequences of a strictly literal biblical interpretation -- here concerning the Earth's shape, disc versus sphere, there the geocentric versus the heliocentric system. This thorough philosophical study is followed by two very short articles. "The measuring accuracy of Tycho's large sextant" by Johann Wünsch investigates O-C values of planet-star distances, as based on Tycho's observations as published in the Historia Coelestis (a compilation, which is also based on Tycho's manuscripts, and published in Regensburg in 1672). The result is that standard deviations are 80 arcseconds for Saturn and 89 arcseconds for Jupiter and Mars, an unexpectedly poor result in view of the general opinion that Tycho was famous for his precision work. "The astronomer Christoph Grienberger and the Galilei trial" by Franz Daxecker deals with a Jesuit astronomer who was both the disciple and successor of the mathematician-astronomer Christopher Clavius at the Collegium Romanum. While he was inclined to Galilei early on, he was forced to propagate Aristotelian doctrine. The brief article is very concise, but extremely tiresome to read (3 pages of pure text are embellished by

  12. Review of the Journal Acta Informatica Medica During Eight Year Period: 2008-2015.

    Masic, Izet; Begic, Edin; Zunic, Lejla


    Acta Informatica Medica is official journal of the Academy for Medical Sciences of Bosnia and Herzegovina (from 2014 Acta Inform Med is published bimonthly). To evaluate journal "Acta Informatica Medica" in 2015 and compare findings to previous years. The study has retrospective and descriptive character, and included the period 2008-2015 (included 36 issues of journal). A total of 83 (average 13,8 articles per journal) articles were published in Acta Informatica Medica during 2015. Analyzing the type of articles, original articles are present in majority during 2015 (68,6%) (by analyzing last eight years, 310 (67,3%) were original). During 2015, 27,7% of articles were related to the applied of Health informatics in field of clinical medicine, 63,8% preclinical medicine and 8,5% to public health. Collaboration rate in 2015 was 0,84. Most often the time required for decision on acceptance of article in 2015 is between 50 and 60 days. Articles came from 16 countries. According to for 2014, Acta Informatica Medica has SCImago Journal Rank 0,166, while Cites / Doc. (2 years) parameter (widely used as impact index) is 0,70. According to GoogleScholar, h5 index is 11 and h5 median is 19. We analyzed the Acta Informatica Medica by "Publish or Perish" software - H index was 14, g index was 19 and e-index was 10.39. Year after year the highest number of original articles are published. Although the period of revision of articles is acceptable, the period up to two months is certainly not long, the goal is to reduce this period. Although the magazine in mentioned field found its place, although it is indexed in numerous bases, including: PubMed, PubMed Central, SCOPUS, EMBASE, EBSCO, etc. The main goal for next year is that the magazine becomes part of the Web of Science. Imperative is further internationalization of the magazine.

  13. Priscilianistas: Actas del I Concilio de Toledo recopiladas por Bartolomé Carranza

    Ruiz de Pablos, Francisco


    Full Text Available In the current article, the author provides some documents which demonstrate that Bartolomé Carranza, (Archbishop from Toledo was the first person who compiled the «Actas from the 1st Council of Toledo», against the theory sustained by Chadwick since 1978.

    En el presente artículo el autor aporta documentos que demuestran que Bartolomé Carranza, arzobispo de Toledo, fue el primer recopilador de las Actas del I Concilio de Toledo, en contra de la teoría sostenida por Chadwick desde 1978.

  14. Acta Dermatovenerologica Alpina, Pannonica et Adriatica accepted for coverage in Thomson Reuters' Emerging Sources Citation Index (ESCI).

    Poljak, Mario; Miljković, Jovan; Triglav, Tina


    Acta Dermatovenerologica Alpina, Pannonica et Adriatica (Acta Dermatovenerol APA) is the leading journal in dermatology and sexually transmitted infections in the region. Several important steps were taken during the last 25 years to improve the journal's quality, global visibility, and international impact. After a 1-year trial period, Thomson Reuters recently informed the editorial office that they had accepted Acta Dermatovenerol APA for coverage in Thomson Reuters' new index in the Web of Science Core Collection called the Emerging Sources Citation Index (ESCI). The coverage of Acta Dermatovenerol APA begins with the journal content published online in 2016; that is, from volume 25 onwards.

  15. “Showing respect” in bible translation | van der Spuy | Acta Theologica

    Acta Theologica. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 30, No 1 (2010) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if ...

  16. “Bond of love”: The action of the spirit | Williams | Acta Theologica

    Acta Theologica. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 34, No 2 (2014) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if ...

  17. Twentieth-century English Bible translations | Naudé | Acta Theologica

    Acta Theologica. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 25, No 2 (2005) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if ...

  18. Citation analysis of Acta Dermatovenerologica Alpina, Pannonica et Adriatica: 1992-2011.

    Ostrbenk, Anja; Skamperle, Mateja; Poljak, Mario


    Acta Dermatovenerologica Alpina, Pannonica et Adriatica is small regional professional journal that started publishing in 1992. Despite the journal's relatively narrow readership, it has significantly improved its quality and global profile during the last 20 years, as shown in this citation analysis update. Since 1992, 654 bibliographical items have been published. Among these, 545 (83.4%) were considered WoS citable items and 109 (16.6%) WoS noncitable items. Since 2008, 90% of all published items have been considered WoS citable items and received an average of 1.9 citations per item. The predicted Acta Dermatovenerol APA impact factor calculated using data from a Cited Reference search of Thomson Scientific's Web of Science has shown steep and continuous increase since 2006, when the journal acquired full indexing status in Index Medicus/Medline, and has been above 0.5 since 2008.

  19. Acta Alexandrinorum: questionamento dos Alexandrinos às praticas imperiais romanas

    Joana Campos Clímaco


    Full Text Available The aim of this article is to illustrate the context of criticism and questioning towards the roman power in a documentation named by its editors as Acta Alexandrinorum. Through the analyses of common themes present in the selected texts, the main idea of is to investigate the initial motivation for the writing of the texts, that were spread as a kind of literary resistance of the Alexandrians towards the Empire in the II and III centuries.

  20. R179H mutation in ACTA2 expanding the phenotype to include prune-belly sequence and skin manifestations.

    Richer, J; Milewicz, D M; Gow, R; de Nanassy, J; Maharajh, G; Miller, E; Oppenheimer, L; Weiler, G; O'Connor, M


    Mutations in ACTA2 (smooth muscle cell-specific isoform of α-actin) lead to a predisposition to thoracic aortic aneurysms and other vascular diseases. More recently, the ACTA2 R179H mutation has been described in individuals with global smooth muscle dysfunction. We report a patient heterozygous for the mutation in ACTA2 R179H who presented with megacystis at 13 weeks gestational age and, at birth, with prune-belly sequence. He also had deep skin dimples and creases on his palms and soles, a finding not previously described but possibly related to ACTA2. To our knowledge, this is the first report of the R179H mutation in ACTA2 in a child with prune-belly sequence. We think the R179H mutation in ACTA2 should be included in the differential diagnosis of individuals presenting with the sequence without an identified mechanical obstruction. Furthermore, as ACTA2 R179H has been reported in patients with severe vasculomyopathy and premature death, we recommend that molecular testing for this mutation be considered in fetuses presenting with fetal megacystis with a normal karyotype, particularly if the bladder diameter is 15 mm or more, to allow expectant parents to make an informed decision. Copyright © 2012 Wiley Periodicals, Inc.

  1. Bibliography of Soviet Laser Developments, Number 67, September-October 1983.


    hungaricae APOBB Acta physica polonica . Series B APSVC Acta physica slovaca APYCA Acta physica et chemica. Szeged ARPTA Arkhiv patologii ATPLB Acta ...77 IV SOURCE ABBREVIATIONS (Note: CTC acover-to-cover translation available) APAHA Acta physica academiae scientiarum... physica polonica . Series A AVMEB Avtometriya (CTC) BPPHA Beitraege aus der Plasmaphysik CKCFA Ceskoslovensky casopis pro fysiku CMSSMODD Mezhvedomstvennoye

  2. Autosomal dominant distal myopathy due to a novel ACTA1 mutation.

    Liewluck, Teerin; Sorenson, Eric J; Walkiewicz, Magdalena A; Rumilla, Kandelaria M; Milone, Margherita


    Mutations in skeletal muscle α-actin 1-encoding gene (ACTA1) cause autosomal dominant or recessive myopathies with marked clinical and pathological heterogeneity. Patients typically develop generalized or limb-girdle pattern of weakness, but recently a family with scapuloperoneal myopathy was reported. We describe a father and 2 children with childhood-to-juvenile onset distal myopathy, carrying a novel dominant ACTA1 variant, c.757G>C (p.Gly253Arg). Father had delayed motor development and developed significant proximal weakness later in life; he was initially misdiagnosed as having spinal muscular atrophy based on electromyographic findings. His children had predominant anterior distal leg and finger extensor involvement. Nemaline rods were abundant on the daughter's biopsy, absent on the father's initial biopsy, and extremely rare on the father's subsequent biopsy a decade later. The father's second biopsy also showed myofibrillar pathology and rare fibers with actin filament aggregates. The present family expands the spectrum of actinopathy to include a distal myopathy. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. The ACTA PORT-score for predicting perioperative risk of blood transfusion for adult cardiac surgery.

    Klein, A A; Collier, T; Yeates, J; Miles, L F; Fletcher, S N; Evans, C; Richards, T


    A simple and accurate scoring system to predict risk of transfusion for patients undergoing cardiac surgery is lacking. We identified independent risk factors associated with transfusion by performing univariate analysis, followed by logistic regression. We then simplified the score to an integer-based system and tested it using the area under the receiver operator characteristic (AUC) statistic with a Hosmer-Lemeshow goodness-of-fit test. Finally, the scoring system was applied to the external validation dataset and the same statistical methods applied to test the accuracy of the ACTA-PORT score. Several factors were independently associated with risk of transfusion, including age, sex, body surface area, logistic EuroSCORE, preoperative haemoglobin and creatinine, and type of surgery. In our primary dataset, the score accurately predicted risk of perioperative transfusion in cardiac surgery patients with an AUC of 0.76. The external validation confirmed accuracy of the scoring method with an AUC of 0.84 and good agreement across all scores, with a minor tendency to under-estimate transfusion risk in very high-risk patients. The ACTA-PORT score is a reliable, validated tool for predicting risk of transfusion for patients undergoing cardiac surgery. This and other scores can be used in research studies for risk adjustment when assessing outcomes, and might also be incorporated into a Patient Blood Management programme. © The Author 2017. Published by Oxford University Press on behalf of the British Journal of Anaesthesia. All rights reserved. For Permissions, please email:

  4. Bibliography of Soviet Laser Developments, Number 79, September - October 1985.


    hungarica (Budapest) (formerly APAHA) APYCA Acta physica et chemica. Szeged ATPLB Acta physica polonica . Series A AVMEB Avtometriya (CTC) BPBEE...cover translation available) AKZHA Akusticheskiy zhurnal (CTC) APAHA Acta physica acadeniiae scientiarum hungaricae (flow APHUE) APHUE Acta physica ...Pribory i tekhnika eksperimenta (CTC) PSSAB Physica status solidi (A). Applied Research (GDR) PSSBB Physica status solidi (B). Basic Research (GDR

  5. Elsevier’s CiteScore index values for Acta Dermatovenerologica Alpina, Pannonica et Adriatica: a 2016 update

    Šterbenc, Anja; Oštrbenk, Anja


    Elsevier’s recently launched citation metric CiteScore enables comprehensive, transparent, and current evaluation of a journal’s performance. For an editorial office, insight into a journal’s impact over time is of great value when making important decisions regarding the journal’s future. A 2016 update of CiteScore index values for Acta Dermatovenerologica Alpina, Pannonica et Adri- atica (Acta Dermatovenerol APA) showed a slight decrease in the CiteScore index value from 1.18 in 2015 to 0.96 in 2016. Acta Dermatovenerol APA can still be considered the principal journal in the field of dermatology and sexually transmitted infections in our region, with almost half of the articles published between 2013 and 2015 cited at least once in 2016. Acta Dermatovenerol APA performed well in both categories listed because it ranked 67th out of 121 journals in the category Dermatology (44th percentile) and 175th out of 250 journals in the category Infectious Diseases (30th percentile).

  6. Vergifnis in die gebed van Daniël (Dan. 9:4-19) | O'Kennedy | Acta ...

    Everyone is guilty - the guilt is not placed on a certain person or king (cf. v. 7); (4) Forgiveness is meant for the "international" Israel and not limited to a specific geographical area. Keywords: Ou Testament, Gebed, Vergifnis, Daniel 9: 4-19, Old Testament, Prayer, Forgiveness Acta Theologica Vol.22(1) 2003: 135-149.

  7. TetR-dependent gene regulation in intracellular Listeria monocytogenes demonstrates the spatiotemporal surface distribution of ActA.

    Schmitter, Sibylle; Fieseler, Lars; Klumpp, Jochen; Bertram, Ralph; Loessner, Martin J


    To enable specific and tightly controlled gene expression both in vitro and during the intracellular lifecycle of the pathogen Listeria monocytogenes, a TetR-dependent genetic induction system was developed. Highest concentration of cytoplasmic TetR and best repression of tetO-controlled genes was obtained by tetR expression from the synthetic promoter Pt 17 . Anhydrotetracycline (ATc) as inducer permitted concentration-dependent, fine-tuned expression of genes under control of the tetO operator and a suitable promoter. The actin-polymerizing ActA protein represents a major virulence factor of L. monocytogenes, required for actin-based motility and cell-to-cell spread in infected host cells. To be able to observe its spatial and temporal distribution on intracellular L. monocytogenes cells, conditional mutants featuring actA placed under TetR control were used to infect PtK2 epithelial cells. Following induction at different time intervals, the subsequent recruitment of actin by L. monocytogenes could be monitored. We found that cells displayed functional ActA after approximately 15 min, while formation of polarized actin tail was complete after 90-120 min. At this point, intracellular motility of the induced mutants was indistinguishable from wild-type bacteria. Interestingly, de novo ActA synthesis in intracellular Listeria also demonstrated the temporal, asymmetric redistribution of the membrane-anchored proteins from the lateral walls toward the cell poles. © 2017 John Wiley & Sons Ltd.

  8. Gender analysis of papers published in ACTAS ESPANOLAS DE PSIQUIATRIA (1999-2006).

    Alonso-Arroyo, A; González-Alcaide, G; Bolaños Pizarro, M; Castelló Cogollos, L; Valderrama-Zurián, J C; Aleixandre-Benavent, R


    The governments and organizations responsible for scientific policies try to encourage equality of gender, among their priorities that of obtaining equal participation and full integration of women in all aspects of the scientific profession. The study analyzes the scientific production of women in the areas of Psychiatry by means of the bibliometric study of the papers published in ACTAS ESPANOLAS DE PSIQUIATRIA. A total of 458 papers published from 1999- 2006 period were downloaded from the Science Citation Index-Expanded database, these including original research papers, review articles and clinical cases. A bibliometric study broken down by gender was carried out to determine the existence or inequalities between men and women regarding scientific productivity, type of document, order of author signatures, on the institutional and geographical level. The papers were published by 1,194 different authors. The gender of 977 authors was identified, 587 (60.08%) men and 390 (39.92%) women. The percentage of women authorship has risen from 29.92% in 1999 to 38.86% in 2006. A total of 42.92% of authors having one published article were women, while (those with more than nine articles) only accounted for 33%. Bibliometric studies on scientific activity provide essential information to promote gender equality. An annual increase over 1% in the number of female authors in the journal has been observed, which if it continues will lead to a parity in coming years.

  9. The Acta Comparationis Litterarum Universarum (1877–1888 from the Perspective of its British Collaborators

    Annamária Codău


    Full Text Available Within a contemporary Hungarian literary discourse that emphasized national values, the first international journal of comparative literature, Acta Comparationis Litterarum Universarum (ACLU proved quite incomprehensible. I therefore argue that ACLU’s aims and constant struggles are better understood from the viewpoint of its authors originating from beyond Hungary, such as that held by the English collaborator, E. D. Butler. A librarian at the British Museum whose interest in antiquarianism and orientalism may have fueled his involvement in ACLU’s translation projects, Butler can be considered one of the most important channels for propagating Hungarian literature in England. A comparison of Hungarian and English perspectives reveals how differently ACLU’S goals were interpreted, how comparative literature and Hungarian Studies/Hungarology were balanced according to the project proposed by the journal’s editors, Meltzl and Brassai. This analysis further examines how this negotiation surrounding the journal’s interpretation came to determine the early period of institutional comparative literature. Similarly, the Hungarian and English press’s reactions to this project reveal the paradoxical position ACLU occupied; for Hungarians, ACLU was not “Hungarian” enough, while it was precisely this “Hungarianness” that attracted the English. My paper discusses the underlying reasons for this situation by examining how Hungarians, the English and ACLU addressed questions in folklore, Hungarian and comparative literature studies, thereby providing additional insight into the journal’s concept of world literature and its anthropological approach.

  10. Intellectual Property and the Tourism Industry: From ACTA Protests towards a Restrictive Interpretation of Innovation Regulations

    Speriusi-Vlad Alin


    Full Text Available In 2012 became reality James Boyle’s desire exposed in his essay from 1997 regarding a politics of intellectual property concerning the great deal of attention that must be paid to the Intellectual Property. At that time Boyle was disappointed by the lack of attention from lawyers, scholars, legal academics and the media for the Clinton administration’s proposal for copyright on the Net, a document that provided the blueprint of domestic and international regulatory efforts to expand intellectual property rights. Certainly this was not the case with ACTA where the public media forced by the private citizen’s protests tried to weight both the benefits and the costs of the new protection standards brought by the new international convention. After those moments Intellectual Property regulations are no more an esoteric and arcane field, something that is only interesting and comprehensible to the practitioners in the field, but a matter of public interests like the environment which arouse the attention of all the persons. In this way we all become aware that intellectual property radiates beyond the legal frame and interferes with several aspects of our lives, including our free time and the tourism consequently.

  11. Generation of an efficient artificial promoter of bovine skeletal muscle α-actin gene (ACTA1) through addition of cis-acting element.

    Hu, Qian; Tong, Huili; Zhao, Dandan; Cao, Yunkao; Zhang, Weiwei; Chang, Shuwei; Yang, Yu; Yan, Yunqin


    The promoter of skeletal muscle α-actin gene (ACTA1) is highly muscle specific. The core of the bovine ACTA1 promoter extends from +29 to -233, about 262 base pairs (bp), which is sufficient to activate transcription in bovine muscle satellite cells. In this study, analysis by PCR site-specific mutagenesis showed that the cis-acting element SRE (serum response element binding factor) was processed as a transcriptional activator. In order to enhance the bovine ACTA1 promoter's activity, we used a strategy to modify it. We cloned a fragment containing three SREs from the promoter of ACTA1, and then one or two clones were linked upstream of the core promoter (262 bp) of ACTA1. One and two clones increased the activity of the ACTA1 promoter 3-fold and 10-fold, respectively, and maintained muscle tissue specificity. The modified promoter with two clones could increase the level of ACTA1 mRNA and protein 4-fold and 1.1-fold, respectively. Immunofluorescence results showed that green fluorescence of ACTA1 increased. Additionally, the number of total muscle microfilaments increased. These genetically engineered promoters might be useful for regulating gene expression in muscle cells and improving muscle mass in livestock.

  12. Analysis of historical articles published in Actas Urológicas Españolas.

    Pérez-Albacete, M

    On the 40th anniversary of the edition of Actas Urológicas Españolas, we assess the articles on history to determine the proportion represented, analysing the study subjects and their relevance, getting to know the authors, the main study centres and the interest that the studies offer for understanding the specialty. We extracted as many subjects of historic content from the journal as were published between January 1976 and December 2016. There were 103 historical studies representing 3% of the total number of articles, with a mean of 2.57 articles published annually, written by 127 separate urologists. As first author, there were 59 articles, and as coauthors, there were 68. The main activity came from 21 of the main university hospitals in Spain, and 43 of the articles were personal articles signed by a single individual. Their content mainly covers the facts of Spanish urology from the Renaissance to the 20th century, with special emphasis on the profile of Spanish specialists. Data on 22 of these specialists are provided in 37 articles. The evolution of diagnostic and treatment procedures, both medical and surgical, are well reflected, as are a number of diseases. Most of the studies are personal works of historical research and represent 3% of the total number of articles. As a whole, the quality is high, and the articles provide data with interesting details and useful reviews, giving them considerable value, as well as forming a precious compendium for the understanding of the history of Spanish urology. These articles are highly recommended reading. Copyright © 2017 AEU. Publicado por Elsevier España, S.L.U. All rights reserved.

  13. Book Review: Beitraege zur Astronomiegeschichte, Band 5 (Acta Historica Astronomiae Vol. 15)

    Duerbeck, H. W.; Dick, W. R.; Hamel, J.


    The 15th volume of the Acta Historica Astronomiae is at the same time the fifth collection of essays on the history of astronomy (Beitraege zur Astronomiegeschichte, Band 5), edited by the historians of astronomy W.R. Dick (Potsdam) and J. Hamel (Berlin). Besides a few short notices and book reviews, the book contains 11 major articles, which deal with astronomical topics covering the time from the 16th to the 20th centuries. The first article, on the analysis and interpretation of historical horoscopes as a source of the history of science, is based on the inaugural lecture of its author, Guenther Oestmann. After a general introduction, which deals with the principles of horoscope making, the author discusses the horoscope of Count Heinrich Ranzau (1526-1598), the Danish governor of Schleswig-Holstein, who was a friend of Tycho Brahe. Oestmann shows that the astronomical-mathematical basis of such a horoscope can be reconstructed and interpreted. However, it is hardly possible to gain an insight in the process how the interpretation of a horoscope was done in detail. The second and third articles, by Franz Daxecker, deal with Athanasius Kircher and Christoph Scheiner, two catholic astronomers of the 17th century. Kircher's Organum Mathematicum is a calculating device that can be used in the fields of arithmetic, geometry, chronology, astronomy, astrology and others. The author provides extracts of the description of the Organum taken from a book by Caspar Schott, which deal with chronology and astronomy. A photograph of the Organum indicates that this tool consists of a set of tables glued on wooden or cardboard, but details of its contents and applications remain pretty obscure for the reader - a few elaborated examples would have been helpful. The second paper deals with the life of Christoph Scheiner SJ, the co-discoverer of sunspots (next to Galileo), after leaving Rome in 1633 - the year of the Galileo trial. Scheiner spent his later years in the Austrian and

  14. A.C.T.A. and the effects of the agreement on the on-line marketing strategies

    Boitor, A.–B.


    Full Text Available This article presents the most controversial and discussed treaty over the last period and its consequences on the marketing strategies of different companies in fields such as the movie industry, the music industry and the publishing domain. The A.C.T.A. treaty was signed by over 27 countries, and brings up positive effects upon the strategies of those companies which suffer losses from piracy and counterfeiting of intellectual property rights. The paper reflects the changes that the treaty can bring especially to the online marketing strategies of the biggest movie studios and music production labels.

  15. An α-smooth muscle actin (acta2/αsma zebrafish transgenic line marking vascular mural cells and visceral smooth muscle cells.

    Thomas R Whitesell

    Full Text Available Mural cells of the vascular system include vascular smooth muscle cells (SMCs and pericytes whose role is to stabilize and/or provide contractility to blood vessels. One of the earliest markers of mural cell development in vertebrates is α smooth muscle actin (acta2; αsma, which is expressed by pericytes and SMCs. In vivo models of vascular mural cell development in zebrafish are currently lacking, therefore we developed two transgenic zebrafish lines driving expression of GFP or mCherry in acta2-expressing cells. These transgenic fish were used to trace the live development of mural cells in embryonic and larval transgenic zebrafish. acta2:EGFP transgenic animals show expression that largely mirrors native acta2 expression, with early pan-muscle expression starting at 24 hpf in the heart muscle, followed by skeletal and visceral muscle. At 3.5 dpf, expression in the bulbus arteriosus and ventral aorta marks the first expression in vascular smooth muscle. Over the next 10 days of development, the number of acta2:EGFP positive cells and the number of types of blood vessels associated with mural cells increases. Interestingly, the mural cells are not motile and remain in the same position once they express the acta2:EGFP transgene. Taken together, our data suggests that zebrafish mural cells develop relatively late, and have little mobility once they associate with vessels.

  16. Twenty years of society of medical informatics of b&h and the journal acta informatica medica.

    Masic, Izet


    In 2012, Health/Medical informatics profession celebrates five jubilees in Bosnia and Herzegovina: a) Thirty five years from the introduction of the first automatic manipulation of data; b) Twenty five years from establishing Society for Medical Informatics BiH; c) Twenty years from establishing scientific and professional journal of the Society for Medical Informatics of Bosnia and Herzegovina "Acta Informatica Medica"; d) Twenty years from establishing first Cathdra for Medical Informatics on biomedical faculties in Bosnia and Herzegovina and e) Ten years from the introduction of "Distance learning" in medical curriculum. All of the five mentioned activities in the area of Medical informatics had special importance and gave appropriate contribution in the development of Health/Medical informatics in Bosnia And Herzegovina.

  17. Thirty-two years of Acta Neophilologica - with gratitude to its founder and editor Professor Janez Stanonik

    Mirko Jurak


    Full Text Available In spring this year Professor Janez Stanonik decided to retire as the Editor of the scholarly journal Acta Neophilologica, which he founded in 1968 and edited for thirty-two years. I endeavoured to help him with the material side of the journal from the very beginning until1995; since then this task has been performed by the present Associate Editor. At the time when Janez Stanonik began publishing this journal, his main aim was to make our research work in Western European and American literature better known to scholars all over the world. However, in a few years' time the journal also became open to scholars from other countries and other fields, particularly in areas connected with Slovene literature and culture, Slovene immigrant literature, and linguistics. I believe that this approach gave the journal a new openness and that it enriched its quality, therefore I intend to follow this policy in the future too.

  18. La revista Acta Universitaria: su Trayectoria a Diez años de su Publicación Inicial

    Esperanza R. Vargas Pacheco


    Full Text Available In the latter part of the XIX century Don Vicente Fernández, professor of the Colegio del Estado, proposed that a journal should be edited covering scientific themes such as mathematics, physics, chemistry, zoology, botany, mineralogy and astronomy. His idea became a reality when in 1991 the Universidad de Guanajuato edited a journal,Acta Universitaria, with the characteristics that he had proposed. Ever since 17 issues have been published containing articles that come from different disciplines including sciences, social sciences, humanities, business and economics. A great number of these articles have been contributions of professors in the areas of agriculture, biology, chemistry, physics, medicine and engineering. In addition, other topics covered have been philosophy and other humanities. In the present article the evolution of the journal is examined to determine how many national and international articles have been published in the journal and the contribution of the academic units of the Universidad de Guanajuato as well. Desde fines del siglo XIX Don Vicente Fernández, profesor del Colegio del Estado propuso que se editara una publicación periódica que versara sobre temas científicos como Matemáticas, Física, Química, Zoología, Botánica, Mineralogía y Astronomía. A partir de 1991 la Universidad de Guanajuato edita una revista con tal propósito que es Acta Universitaria. De esta publicación se han editado con el presente 17 números que contienen artículos en las distintas áreas del conocimiento, incluyendo las científicas, sociales, humanísticas y económico-administrativas. De los artículos publicados la mayor parte han sido contribuciones de profesores del área de ciencias agrícolas, biología, química, física, médicas e ingenierías. Aunque también existe una aportación importante de filosofía y en general de las humanidades. Se revisa la revista y su evolución analizando cuantas y que instituciones

  19. Coverage of Acta Dermatovenerologica Alpina, Pannonica et Adriatica in Elsevier's CiteScore index: a new tool for measuring the citation impact of academic journals.

    Poljak, Mario


    In December 2016, Elsevier launched a new tool that helps measure the citation impact of academic journals, called the CiteScore index. The CiteScore index values for 2015 confirmed the status of Acta Dermatovenerologica Alpina, Pannonica et Adriatica (Acta Dermatovenerol APA) as the leading journal in dermatology and sexually transmitted infections in the region. Sixty-five articles published in Acta Dermatovenerol APA from 2012 to 2014 received a total of 77 citations in 2015, resulting in a CiteScore index value of 1.18 for the journal. More than half of the articles published from 2012 to 2014 received at least one citation in 2015. Acta Dermatovenerol APA performed well in all three categories listed because it is ranked 384th out of 1,549 journals in the category General Medicine (75th percentile), 53rd out of 122 journals in the category Dermatology (56th percentile), and 142nd out of 246 journals in the category Infectious Diseases (42nd percentile).

  20. A Novel Regulatory Mechanism of Smooth Muscle α-Actin Expression by NRG-1/circACTA2/miR-548f-5p Axis.

    Sun, Yan; Yang, Zhan; Zheng, Bin; Zhang, Xin-Hua; Zhang, Man-Li; Zhao, Xue-Shan; Zhao, Hong-Ye; Suzuki, Toru; Wen, Jin-Kun


    Neuregulin-1 (NRG-1) includes an extracellular epidermal growth factor-like domain and an intracellular domain (NRG-1-ICD). In response to transforming growth factor-β1, its cleavage by proteolytic enzymes releases a bioactive fragment, which suppresses the vascular smooth muscle cell (VSMC) proliferation by activating ErbB (erythroblastic leukemia viral oncogene homolog) receptor. However, NRG-1-ICD function in VSMCs remains unknown. Here, we characterize the function of NRG-1-ICD and underlying mechanisms in VSMCs. Immunofluorescence staining, Western blotting, and quantitative real-time polymerase chain reaction showed that NRG-1 was expressed in rat, mouse, and human VSMCs and was upregulated and cleaved in response to transforming growth factor-β1. In the cytoplasm of HASMCs (human aortic smooth muscle cells), the NRG-1-ICD participated in filamentous actin formation by interacting with α-SMA (smooth muscle α-actin). In the nucleus, the Nrg-1-ICD induced circular ACTA2 (alpha-actin-2; circACTA2) formation by recruitment of the zinc-finger transcription factor IKZF1 (IKAROS family zinc finger 1) to the first intron of α-SMA gene. We further confirmed that circACTA2, acting as a sponge binding microRNA (miR)-548f-5p, interacted with miR-548f-5p targeting 3' untranslated region of α-SMA mRNA, which in turn relieves miR-548f-5p repression of the α-SMA expression and thus upregulates α-SMA expression, thereby facilitating stress fiber formation and cell contraction in HASMCs. Accordingly, in vivo studies demonstrated that the localization of the interaction of circACTA2 with miR-548f-5p is significantly decreased in human intimal hyperplastic arteries compared with normal arteries, implicating that dysregulation of circACTA2 and miR-548f-5p expression is involved in intimal hyperplasia. These results suggest that circACTA2 mediates NRG-1-ICD regulation of α-SMA expression in HASMCs via the NRG-1-ICD/circACTA2/miR-548f-5p axis. Our data provide a molecular

  1. Acta Structilia: Editorial Policies

    Dr K Agyekum (Department of Building Technology, Kwame Nkrumah ... Mr A Kerin (President, Slovenian Project Management Association, Slovenia) ... Subscription information and subscription forms can be obtain form the editorial office:.

  2. Archives: Acta Theologica

    , No 2 (2017). 2016. Vol 36, No 1 (2016) · 2016: SUPPLEMENTUM 23. 2015. Vol 35, No 2 (2015) · Vol 35, No 1 (2015) · 2015: SUPPLEMENTUM 21 · 2015: SUPPLEMENTUM 22. 2014. Vol 34, No 2 (2014) · Vol 34, No 1 ...

  3. Acta Structilia: Submissions

    After that use a) etc. 11. Source references in the text must be in the Harvard style of referencing (Author, date: pages). i. e. (Schleien, 2006: 20-40). 12. Foot- and endnotes are likewise done in the Harvard style of referencing. 13. The references list (Harvard style of referencing) should contain all the relevant information, ...

  4. Acta Theologica - 2014

    Freedom in the sense of the Heidelberg Catechism – an orientation in the ... Learning theological ethics through the Heidelberg Catechism · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT ... What profit is the reign of Christ to us?

  5. Acta Theologica - Supplementum 17

    Pavel Aleksadrovič Florenskij's method of discerning spiritual truth · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. C Camilleri, 228-246. ...

  6. Bibliography of Soviet Laser Developments, Number 84, July - August 1986.


    physica et chemica. Szeged ATPLB Acta physica polonica . Series A AUONA Acta Universitatis Palackianae Olomucensis. Facultas rerum naturalium. Physica ...holographic mirrors. OPSPA, vol. -, 61, no. 2, 1986, 398-402. 522. Kaluzny, J. 0. Recording of acoustic holograms (in English). Acta physica Universitatis...168 p. (RZFZA, 86/7A42-44). 88 IV. SOURCE ABBREVIATIONS (Note: CTC - cover-to-cover translation available) AKZHA Akusticheskiy shurnal (CTC) APYCA Acta

  7. Bibliography of Soviet Laser Developments Number 57, January-February 1982.


    scientiarwn hungaricae APP (APTLB) Acta physica polonica BAPS (BAPTA) Bulletin de l’Academie Polonaise des Sciences. Serie des Sciences Techniques BIPC (BIPED...nonlinear absorption of light. Acta physica slovenia, no. 4, 1981, 249-255. (RZhF, 1/82, 1D1494) 263. Kurbatov, A.A., and T.Ya. Popova (193). Resonance...Nauka. 1982, 177 p. 133 IV. SOURCE ABBREVIATIONS (CIRC Codens) APC (APYCA) Acta physica et, chemica. Szeged APH (APAHA) Acta physica Academiae

  8. Acta Cirúrgica Brasileira. Visibilidade e acessibilidade da produção científica na área da cirurgia experimental

    Población Dinah Aguiar


    Full Text Available A visibilidade da ciência divulgada pela Acta Cirúrgica Brasileira é analisada ao longo da trajetória de 15 anos de publicação ininterrupta, durante a qual foi mantida a periodicidade proposta. Com isto obteve os créditos necessários, para ser selecionada por autores nacionais e estrangeiros que publicaram 116 artigos no primeiro qüinqüênio (1986-1990, 170 no segundo qüinqüênio (1991-1995 e 190 no terceiro qüinqüênio (1996-2000 e também para ser inserida na Base LILACS desde 1987. A partir de maio de 1998 foi credenciada, entre os periódicos brasileiros da área da saúde, para ser incorporada ao Projeto SciELO Brasil. Os indicadores da Base SciELO permitem avaliar a posição da ACTA quanto às características formais de publicação revelando a qualidade científica por meio dos relatórios de uso do "site", acesso aos artigos e às revistas citantes. Análises cienciométricas são realizadas para avaliar a visibilidade e acessibilidade da literatura científica publicada na ACTA.

  9. [Bibliometric study of Actas Dermo-sifiliográficas (1984-2003) III. Analysis of bibliographic impact factors].

    Miralles, Julia; Ramos, José M; Ballester, Rosa; Belinchón, Isabel; Sevila, Amparo; Moragón, Manuel


    To quantify the impact factor of the journal Actas Dermo-Sifiliográficas (AD) from 1986 to 1990 and from 1999 to 2003 and to identify the journal's citation pattern in those years. Citations obtained by AD in the periods from 1985-1990 and 1998-2003 for articles published from 1984 to 1989 and from 1997 to 2002 were collected using Science Citation Index Expanded (SCI). The number of times AD was cited doubled during the second period, increasing from 38 (period from 1985-1990) to 76 (period from 1998-2003). Considering the number of citations, AD's impact factor increased from 0.016 in 1986 to 0.040 in 2003. In both periods, citations corresponding to AD articles were included in a wide range of source journals, mainly dermatological publications abroad. The most referred journals in the second period were the Dutch publication Journal of the European Academy of Dermatology and Venereology (13 citations) and the Journal of the American Academy of Dermatology (12 citations). Unlike the period from 1985 to 1990 when no Spanish journal cited AD, four Spanish publications mentioned AD in the second period: Revista clínica española (6 citations), Archivos de bronconeumología (4 citations), Medicina clínica (3 citations) and the journal Enfermedades infecciosas y microbiología clínica (1 citation). Citations mainly corresponded to articles published by Spanish authors (63.2 % in the 1985-1990 period and 81.6 % in the period from 1998 to 2003). Self-citation increased from 10.5 % (first period) to 31.6 % (second period). The impact factor of AD is low and not comparable to other publications included in the Dermatology and Venereal Diseases field from SCI. Our results confirm the low citation rate of AD by source journals in this repertory. However, the increase of this rate in recent years seems to indicate a higher Spanish presence in SCI due to an increasing number of publications corresponding to Spanish authors in international journals and the inclusion of

  10. BOOK REVIEW: Astronomie von Olbers bis Schwarzschild. Nationale Entwicklungen und internationale Beziehungen im 19. Jahrhundert (Acta Historica Astronomiae Vol. 16)

    Sterken, C.; Dick, W. R.; Hamel, J.


    The 14th volume of the Acta Historica Astronomiae is the Proceedings of a Colloquium International Relationships in Astronomy (in German) organised by the History of Astronomy Section of the Astronomische Gesellschaft held on September 18 in Lilienthal, Germany. The book contains 13 articles on astronomical topics covering the 19th and 20th centuries. The first paper is by Guenther Oestmann and deals with contemporary assessments of Johann Hieronymus Schroeter's (1745-1816) astronomical works and with later judgements of the scientific importance and significance of his observations as seen by astronomers and historians. This report is complemented by a second article on Schroeter's 25-ft reflector in Lilienthal near Bremen. To this end, author Felix Luehning has constructed a scale model of the telescope, and shows how the building of a model brings a deeper understanding of function and handling of this instrument. This brings us to a third paper on telescope building in Lilienthal: Hans-Joachim Leue describes the cooperation of Johann Hieronymus Schroeter and Johann Gottlieb Schrader in developing a white reflecting metal alloy for use as telescope mirror. The fourth article, by Klaus Schillinger, describes on the basis of archival documents the aquisition history of the Herschel telescopes, including telescope quality check, repair and building. Memorial sites referring to Wilhelm Olbers, Johann Hieronymus Schroeter, Friedrich Wilhelm Bessel and Carl Friedrich Gauss are described by Arno Langkavel in two walks outlined in the very last paper of this book. Peter Brosche, in the fifth paper, discusses the rediscovery of Ceres in December1801, a discovery that was the result of the combined efforts of a theoretician (Gauss) and an observer (Zach). Juergen Hamel's paper is based on previously unused archival sources and discusses the outstanding role played by H. C. Schumacher (1780-1850, editor of the Astronomische Nachrichten) in the communication between

  11. Christo Deltshev & Pavel Stoev (eds) (2006): European Arachnology 2005, Acta zoologica bulgaria, Suppl. No. 1; Proceedings of the 22nd European Colloquium of Arachnology, Blagoevgrad, Bulgaria, 1-6 August 2005

    Kunz, Dirk


    book review: Christo Deltshev & Pavel Stoev (eds) (2006): European Arachnology 2005, Acta zoologica bulgaria, Suppl. No. 1; Proceedings of the 22nd European Colloquium of Arachnology, Blagoevgrad, Bulgaria, 1-6 August 2005

  12. Bibliography of Soviet Laser Developments, September-October 1987


    akustyki (Warsaw) ATPLB Acta physica polonica . Series A AVMEB Avtometriya (CTC) BITOA Bild und Ton (East Berlin) CICWIPla International Congress on Waves and... Acta Academiae Paedagogicae Szegediensis. Seria physica , chemica, mathematica. 1985, 3-13. (RZFZA, 87/10L936). 199. Vasil’yev, N.F. (SFTI). Theory of the...translation available) AENGA Atomnaya energiya (CTC) AKZHA Akusticheskiy zhurnal (CTC) APHUE Acta physica hungarica (Budapest) ARAKB Archiwum

  13. For a better visibility: changes in notes for contributors Acta Scientiarum. Technology - doi: 10.4025/actascitechnol.v34i1.15289

    Nilson Evelázio de Souza


    Full Text Available O Fator de Impacto de 2009 da Acta Scientiarum. Technology pelo JCR foi 0,276 e o de 2010 é 0,150. O Objetivo da revista é adquirir maior visibilidade tanto Nacional como Internacional. Nesse contexto, o Conselho Editorial da revista Acta Scientiarum. Technology modificou as normas de submissão a partir de setembro de 2011 (Os artigos submetidos deverão ser em inglês. Os autores devem providenciar uma versão com qualidade. A revista recomenda que oitenta porcento (80% das referências sejam de artigos listados na base ISI Web of Knowledge ou SCOPUS com menos de 10 anos. Recomenda-se dar preferência as citações de artigos internacionais. Não serão aceitos nas referências citações de dissertações, teses, monografias, anais, resumos, resumos expandidos, jornais, magazines e boletins técnicos. Recomenda-se evitar documentos eletrônicos.

  14. A profile of the impact of Acta Botanica Brasilica: reflections on how to improve visibility and recognition of a scientific journal Um perfil do impacto da Acta Botanica Brasilica: reflexões acerca de como aumentar a visibilidade e o reconhecimento de um periódico cient��fico

    Fabio Rubio Scarano


    Full Text Available We have estimated the ISI-impact factor of Acta Botanica Brasilica for the past six years, calculated the journal's h-index, calculated the journal's self-citation, examined country and institutions of origin of the papers that cite Acta papers, and examined scope and profile of the most-cited papers published by the journal. Results demonstrated a steep rise in impact factor and citation frequency in 2008, which is most encouraging, but also revealed that the journal is below the level of maturity expected of a 20-year old journal. Visibility of the journal is mostly national although, surprisingly, journal's self-citation of 12% is fairly low. We use Acta as an example to discuss possible strategies to enhance the international visibility of botanical journals that are newcomers to ISI.Este artigo estima o fator de impacto (ISI-Web of Science do periódico Acta Botanica Brasilica para os últimos seis anos, calcula o índice-h do periódico, calcula a sua auto-citação, examina os países e instituições de origem dos artigos que citam artigos da Acta, e examina o escopo e o perfil dos artigos mais citados ao longo da história do periódico. Os resultados demonstraram um aumento substancial no fator de impacto estimado e na freqüência de citação em 2008, o que é muito encorajador, mas também revelaram que o periódico está abaixo do grau de maturidade esperado para um periódico com 20 anos de existência. A visibilidade do periódico é predominantemente nacional embora, surpreendentemente, a auto-citação de 12% seja consideravelmente baixa. A revista é utilizada como exemplo para discutir possíveis estratégias para aumentar a visibilidade internacional de periódicos em botânica recém-indexados no ISI.

  15. [Journal AMHA - Acta medico-historica Adriatica: 14 years of patient work on the scientific valorisation of the history of medicine].

    Eterović, Igor


    In this paper the first 14 years of publication of scientific journal AMHA - Acta medico‑historica Adriatica (2002-2016) are presented and shortly analysed. This journal has undoubtedly become and remained the central activity of the Croatian Scientific Society for the History of Health Culture, which has rapidly become a globally esteemed journal of history of medicine. The beginning and the context of publishing the journal with the reference to scientific meeting "Rijeka and Its Citizens in Medical History" is presented, as well as the journal's profiling into distinguished international journal and its fast development in later years. The analysis shows the growth of journal's visibility through indexation in different international journal databases, the number and ratio of scientific articles and the variety of published material. Finally, a review of the potential future directions of development and the significance of this journal within the national, regional and international context is given.

  16. Elusiyan et al., Afr J Tradit Complement Altern Med. (2011) 8(1):27-33


    -276. 22. Sticher O, Afifi-Yazar FU. (1979). Minecoside and verminoside, two new iridoid glucosides from Veronica officinalis L. (Scrophulariaceae). Helvetica Chimica Acta, 62 (56): 535-539. 23. Tietze LF. (1983). Secologanin, a biogenetic key ...

  17. Iglesia y poder público. Actas del VII Simposio de Historia de la Iglesia en España y América (Reseña)

    Tineo, P. (Primitivo)


    Reseña del libro de Paulino CASTAÑEDA-Manuel J. COCINA Y ABELLA (coords.), Iglesia y poder público. Actas del VII Simposio de Historia de la Iglesia en España y América, Academia de Historia Eclesiástica, Obra social y cultural Cajasur, Córdoba 1997, 308 pp.

  18. Book Reviews | Laubscher | Acta Theologica

    Title: Worship for the whole people of God. Vital worship for the 21st century. Author: Duck, R. (Louisville, KY: Westminster John Knox Press, 2013), pp. xxii + 334. ISBN: 978‑0‑664‑23427‑0. Title: Informed by Science, involved by Christ, How science can update, enrich and empower the Christian faith. Author: K. Nürnberger.

  19. Acta Theologica Supplementum 14 2011

    IT Benson

    greater attention to principles of modus vivendi rather than “convergence” in which .... are divided now from recognition that human life is necessarily lived with “faith” ... Perhaps one of the implicit forms or modern “beliefs” is hidden in the idea.

  20. Presencia musical en la Catedral de La Seu d'Urgell en la primera mitad del siglo XVIII a través de sus actas capitulares

    Roig i Capdevila, Jordi


    Brudieu. Pero, en cambio, apenas se conocen datos sobre la vida musical en esta ciudad episcopal durante los siglos XVIII al XX Empalmando con el final temporal abarcado por el trabajo de Pedrell-Anglés, el presente trabajo inicia el vaciado sistemático de la información alusiva a la música contenida en la documentación catedralicia. Aunque se tiene la intención de continuar, en esta ocasión, solamente se publican las actas capitulares correspondientes al período 1700-1750, lo que nos permite obtener una visión general de las actividades y repercusión de una de las principales capillas de música de ámbito catalán, y uno de los centros de ámbito hispánico menos estudiados por la Musicología hasta el momento.

  1. Combined MRI and ³¹P-MRS investigations of the ACTA1(H40Y mouse model of nemaline myopathy show impaired muscle function and altered energy metabolism.

    Charlotte Gineste

    Full Text Available Nemaline myopathy (NM is the most common disease entity among non-dystrophic skeletal muscle congenital diseases. Mutations in the skeletal muscle α-actin gene (ACTA1 account for ∼25% of all NM cases and are the most frequent cause of severe forms of NM. So far, the mechanisms underlying muscle weakness in NM patients remain unclear. Additionally, recent Magnetic Resonance Imaging (MRI studies reported a progressive fatty infiltration of skeletal muscle with a specific muscle involvement in patients with ACTA1 mutations. We investigated strictly noninvasively the gastrocnemius muscle function of a mouse model carrying a mutation in the ACTA1 gene (H40Y. Skeletal muscle anatomy (hindlimb muscles and fat volumes and energy metabolism were studied using MRI and (31Phosphorus magnetic resonance spectroscopy. Skeletal muscle contractile performance was investigated while applying a force-frequency protocol (from 1-150 Hz and a fatigue protocol (80 stimuli at 40 Hz. H40Y mice showed a reduction of both absolute (-40% and specific (-25% maximal force production as compared to controls. Interestingly, muscle weakness was associated with an improved resistance to fatigue (+40% and an increased energy cost. On the contrary, the force frequency relationship was not modified in H40Y mice and the extent of fatty infiltration was minor and not different from the WT group. We concluded that the H40Y mouse model does not reproduce human MRI findings but shows a severe muscle weakness which might be related to an alteration of intrinsic muscular properties. The increased energy cost in H40Y mice might be related to either an impaired mitochondrial function or an alteration at the cross-bridges level. Overall, we provided a unique set of anatomic, metabolic and functional biomarkers that might be relevant for monitoring the progression of NM disease but also for assessing the efficacy of potential therapeutic interventions at a preclinical level.

  2. Nuevos lineamientos geopolíticos que el Perú podria aplicar al Ecuador a partir de la firma del Acta Presidencial de Brasilia del 26 de octubre de 1998

    Paredes Hernández, Luis


    La presente tesis de Maestría en Seguridad Y Desarrollo se orienta fundamentalmente, a establecer mediante una metodología deductiva los nuevos 7 lineamientos geopolíticos que el Perú podría aplicar al Ecuador a partir de la firma del Acta Presidencial de Brasilia el 26 de octubre de 1998. Para llegar a determinar en forma prospectiva dichos lineamientos se debe acudir, necesariamente, al análisis histórico de las relaciones entre Ecuador y Perú, donde este último, desde ...

  3. Bibliography of Soviet Laser Developments, Number 41, May - June 1979.


    complex molecule in the anisotropic theory of dye amplifiers and lasers. Acta physica polonica , v. A54, no. 6, 1978, 879-888. (RZhF, 6/79, 6D1338) 35...depolarization. Acta physica polonica , v. A54, no. 6, 1978, 823-831. (RZhF, 6/79, 6D1051) 448. Sevchenko, A.N., G.F. Stel’makh, and M.P. Tsvirko (0...of polarization of laser radiation in organic dye solutions. Acta physica et chemica. Szeged, no. 3, 1978, 381-385. (RZhF, 6/79, 6D1340) b

  4. Calvyn oor twyfel | Potgieter | Acta Theologica

    ... sinful human nature, causing anxiety and conflict in the faithful. Although it is part and parcel of Christian life, he condemns it as opposed to the will of God. He does, however, also express his compassion with those suffering under this duress. God expects the faithful to actively resist temptations of doubt and uncertainty.

  5. Discernment in 1 Thessalonians | Sciberras | Acta Theologica

    This article analyses Paul's use of δοκιμάζειν in 1 Thessalonians 5:21 within the context of verbs for discernment (δοκιμάζειν, πειράζειν, διακρίνειν and their cognates). It discusses Paul's use of these verbs against the background of discernment in the Septuaginta. Paul's own understanding of discernment is then further ...

  6. Acta Structilia - Vol 24, No 2 (2017)

    Deciphering priority areas for improving project risk management through critical analysis of pertinent risks in the Zambian construction industry · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Chipozya Kosta Tembo-Silungwe, Nthatisi Khatleli, 1-43.

  7. Acta Theologica - Vol 28, No 2 (2008)

    Le Saint Esprit a yci pourtrait au vif ... Calvin's understanding of the Holy Spirit's modus operandi in the life of believers in the light of the preface to his Commentary on the Psalms · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. L Kayayan, 84-94 ...

  8. Acta Neuropsychiatrica; Tijdschrift voor een hedendaagse neuropsychiatrie.

    Verhey, F H


    Samenvatting De psychiatrie benist op een evenwichtige combinatie van gedragswetenschappelijke (ontwikkelingspsychologische en sociale) en natuurwetenschappelijke (neuropsychiatri-sche) dementen. Ofschoon klinici werkzaam in de gezondheidszorg er vaak in slaagden dit evenwicht rede-lijk te handhaven, werd de officiële psychiatrie tot voor kort meestal nogal modieus gedomineerd door een van deze deelgebieden. Uitgroei tot volwassenheid van de psychiatrie vraagt in deze fase om een aanvulling van de in de laatste decennien sterk tot de verbeelding sprekende psychologische en sociale dementen met de verworvenhe-den van een nieuwe neuropsychiatrie. Geschetst wordt waar uit deze verworvenheden bestaan en hoe deze effectief in de psychiatrische gezondheidszorg onderwijs en onderzoek ingebouwd kunnen worden. Het binnen de psychiatrie tot ontwikkeling brengen van een toegepaste klinische psychofysiologie van essentieel belang.

  9. II Actas Congreso .¿Nuevos feminismos?

    Pinyana i Garí, M. Carme


    ÍNDICE Presentación CONSOL AGUILAR RÓDENAS I. PONENCIAS La representación de la violencia / la violencia de la representación: De Jack el Destripador a Ciudad Juárez, pasando por la pantalla de la televisión,MARÍA RUIDO. Las apostillas al cuerpo: un ámbito de debates feministas, MERI TORRAS. Mujeres jóvenes y movimientos feministas: ¿Una nueva generación de feministas?,SHAMILLAH WILSON. La doble discriminación de las lesbianas,BEATRIZ GIMENO. II. MESAS REDONDAS ...

  10. Hippocrates: facts and fiction | Retief | Acta Theologica

    Hippocrates, the Father of Medicine, is reviewed as a historical person and in terms of his contribution to medicine in order to distinguish fact from fiction. Contemporary and later sources reveal that many (possibly untrue) legends accumulated around this enigmatic figure. The textual tradition and the composition of the ...

  11. Corruption: How should Christians respond? | Theron | Acta ...

    The results of the 2010 Corruption Perceptions Index of Transparency International indicate the seriousness of the worldwide corruption problem. Although recent decades have witnessed a global public awareness and an increase in attempts to eradicate corruption, it is an ongoing problem. It is evident that legislation is ...

  12. Acta Theologica 2010 Supplementum 13 Second Edition


    64) occurs, with an a-theoretical understanding in which the greatest .... recognised qualitative research methods, are further mapped out, with specific ..... pertaining to pastoral care, the focus in the case of futures studies is the.

  13. Praying Through Kenosis | Williams | Acta Theologica

    ... means that prayer is a reality as it really affects God, and changes the future, and, on the other hand, retains the traditional view of God as totally sovereign, which includes his omniscience. Then, if God's approach to people is kenotic, the response of people to God, especially in prayer, should likewise be in the humility of

  14. bladet. Acta Periodica Rerum Interiorum Bibliotecae Universitatis


    Temanummer med billeder, interwievs og personaleberetninger om Syddansk Universitetsbiblioteks afdeling i Østergade i Odense 1968-2007. Redaktører m.m. Erik Hellerup Madsen og Søren Mogensen sammen med redaktørgruppen Projekt Fra Glemmebogen. Yderligere bidrag kan findes i Projekt Fra Glemmebogen....

  15. Mystical Perspectives in Interreligious Dialogue | Waaijman | Acta ...

    The article reflects, first of all, on Paul's reaction to the questions and challenges of the Epicurean and Stoic philosophers in his audience that relates to this distinction. A second part will investigate the mystical unity of the unknowable God and his body language in Christ. In a third part some mystical perspectives on this ...

  16. Acta theologica supplementum 12-2009

    University of the Free State

    alist perspective on the significance of involving the intended audience in the ... churches” is the most important strategy of the United Bible Societies (UBS). ... translation drafts, raising local support, and marketing of the translated Scrip ture.

  17. Acta theologica supplementum 12-2009

    University of the Free State

    This paper compares the use of these terms in English translations with that of episkopos in ..... (literally, elders, from which is derived the transliteration, priests). Moreover, ..... The American Heritage dictionary of the English language. 4th ed.

  18. Acta theologica supplementum 12-2009

    University of the Free State

    radie 1986, De Vries, Willemyns en Burger 1994, Raidt 1980, Van der Wal 1994,. Van Zijl 1992, en Wikipedia, de vrije .... Pare wat gaan trou het, het 'n Statenbijbel as geskenk gekry. Vaders het driemaal per .... verhaal is in tyd en ruimte ver verwyder van die SuidAfrika van Du Toit. Deur gebruik te maak van buitelandse en ...

  19. The death of Cleopatra | Retief | Acta Theologica

    Death occurred very rapidly and the bodies showed no recognisable snake bite wounds. Fatal viper bites are characteristically associated with prominent, swollen and haemorrhagic wounds. Cobras may cause rapid death in spite of minor bite wounds, but in order to kill three adults, the snake would have to be large.

  20. Acta Theologica - Vol 33, No 2 (2013)

    Entering the Corridors of Power: State and Church in the Reception History of Revelation · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL ... When Kingdoms are Kingdoms no more: A social-scientific reading of the Mustard Seed (Lk 13:18-19) · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT

  1. Acta theologica supplementum 12-2009

    University of the Free State

    of Yoruba identity formation and the Yoruba antislavery struggle in the 1800s will help ... identifications across multiple dialects and has given women and lower ... and Catholic liberation theology inflict a certain degree of social disruption on in .... cultural path of Christianity in West Africa from Islam” (Peel 2000:189). Earlier.

  2. What is spirituality? | Waaijman | Acta Theologica

    This essay provides, first of all, a historical perspective on the nature of spirituality by investigating its early forms, followed by a discussion of two approaches in the last century. It then investigates three basic forms of spirituality, concluding with an overview of elements of spirituality.

  3. Conformity in Christ | Waaijman | Acta Theologica

    This essay investigates the notion of conformity in Christ as it is part of a comprehensive, multilayered process of transformation. In the first part it focuses on the process of transformation in creation, re-creation, conformity, love and glory. In the second part it discusses transformation in Christ by looking at conformation and ...

  4. Acta theologica supplementum 12-2009

    University of the Free State

    The Kurumans of the world are now teaching London about mission. The pe ... agency that took the Gospel and its benefits from the centre of the British. Empire and spread them abroad through the work of missionaries and other agents.

  5. First report of Rickettsia raoultii and Rickettsia helvetica in Dermacentor reticulatus ticks from the Czech Republic

    Rudolf, Ivo; Venclíková, Kristýna; Blažejová, Hana; Betášová, Lenka; Mendel, Jan; Hubálek, Zdeněk; Parola, P.


    Roč. 7, č. 6 (2016), s. 1222-1224 ISSN 1877-959X Institutional support: RVO:68081766 Keywords : Rickettsia spp. * Dermacentor spp. * DEBONEL * SENLAT Subject RIV: GJ - Animal Vermins ; Diseases , Veterinary Medicine Impact factor: 3.230, year: 2016

  6. First report of Rickettsia raoultii and Rickettsia helvetica in Dermacentor reticulatus ticks from the Czech Republic

    Rudolf, I.; Venclíková, Kristýna; Blažejová, H.; Betášová, L.; Mendel, J.; Hubálek, Z.; Parola, P.


    Roč. 7, č. 6 (2016), s. 1222-1224 ISSN 1877-959X Institutional support: RVO:61389013 Keywords : Rickettsia spp. * Dermacentor spp. * DEBONEL Subject RIV: CD - Macromolecular Chemistry Impact factor: 3.230, year: 2016

  7. El Espíritu, memoria y testimonio de Cristo. A propósito de la «Tertio Millennio Adveniente», Actas del IX Simposio de Teología histórica (Reseña)

    Luque-Alcaide, E. (Elisa)


    Reseña del libro de Alfonso ESPONERA CERDÁN (ed.), El Espíritu, memoria y testimonio de Cristo. A propósito de la «Tertio Millennio Adveniente», Actas del IX Simposio de Teología histórica, Facultad de Teología San Vicente Ferrer («Series Valentina» 40), Valencia 1997,528 pp.

  8. Daniel Gallego Hernández (Ed.). Enfoques actuales en traducción económica e institucional. Actas del Congreso Internacional de Traducción Económica, Comercial, Financiera e Institucional. Suiça: Editorial Peter Lang, 2015. 254 p.

    Miguel Tolosa Igualada


    Daniel Gallego-Hernández (ed.). Current Approaches to Business and Institutional Translation. Proceedings of the International Conference on Economic, Business, Financial and Institutional Translation / Enfoques actuales en traducción económica e institucional. Actas del Congreso Internacional de Traducción Económica, Comercial, Financiera e Institucional. Suíça: Peter Lang, 2015, 254 páginas. ISBN 978-3-0343-1656-9.

  9. Daniel Gallego Hernández (Ed.. Enfoques actuales en traducción económica e institucional. Actas del Congreso Internacional de Traducción Económica, Comercial, Financiera e Institucional. Suiça: Editorial Peter Lang, 2015. 254 p.

    Miguel Tolosa Igualada


    Full Text Available Daniel Gallego Hernández (Ed.. Enfoques actuales en traducción económica e institucional. Actas del Congreso Internacional de Traducción Económica, Comercial, Financiera e Institucional. Suiça: Editorial Peter Lang, 2015. 254 p.

  10. Synthesis, biological evaluation, and live cell imaging of novel fluorescent duocarmycin analogs.

    Tietze, Lutz F; Behrendt, Frank; Pestel, Galina F; Schuberth, Ingrid; Mitkovski, Mišo


    For a better understanding of the mode of action of duocarmycin and its analogs, the novel fluorescent duocarmycin derivatives 13-15 and 17b-19b were synthesized, and their bioactivity as well as their cellular uptake investigated using confocal laser scanning microscopy (CLSM) in live-cell imaging experiments. Copyright © 2012 Verlag Helvetica Chimica Acta AG, Zürich.

  11. “Una vez triunfantes las armas del ejército francés en Puebla”. De las actas de adhesión de la ciudad de Puebla y de los pueblos en el distrito de Cholula, 1863

    Becerril Hernández, Carlos de Jesús


    Este artículo analiza las opiniones de los habitantes de Cholula y Puebla contenidas en las actas de adhesión al Imperio mexicano redactadas inmediatamente después del triunfo del ejército francés en mayo de 1863. Estos instrumentos jurídicos, pese a las descalificaciones de los historiadores adictos al régimen republicano, representan miradores privilegiados de las primeras impresiones de un sector de la sociedad poblana abiertamente partidaria de la Intervención. Dejando aparte la polémica ...

  12. Bibliography of Soviet Laser Developments. Number 43, September-October 1979.


    Acta physica polonica , v. A55, no. 3, 1979, 307-318. (RZhRadiot, 10/79, lOYe3O) 237. Genin, L.G., S.M. Kuznetsov, and L.V. Sayenko (19). Study on heat...crystals by a Q-switched ruby laser. Acta Physica polonica , v. A55, no. 4, 1979, 531-543. (RZhF, 9/79, 9D1085) 572. Eichler, H.J., J. Eichler, J. Knof, and...N lasers, based on ceramic capacitors. Acta physica et 2- chemica. Szeged, no. 4, 1978, 445-449. (RZhF, 10/79, 10D1060) 2 64. Matyugin, Yu.A., and G.N

  13. United States Air Force Research Initiation Program. 1984 Research Reports. Volume 2.


    differential determination of adrenaline and noradrenaline in plasma." Clinica Chemica Acta. Vol. 30, pp. 373-376, 1970. 37. Stegemann, J., U. Meier, W...34%" . 1. Agh-anian, G. K. and R. Y. Wang. Physiology and Pharma - coloay cf central serotonergic neurons. In: Psych ph cl . j aGe tion A of P M...34, AIAA Journal, Vol. 18, No. 1, January 1980,"[ ’ "<. .’ip p . 1 1 - 1 5 . 39. Rotta, J.C., "Temperaturverteilungen in der Turbulenten Grenzschicht an

  14. Ixodes ricinus ticks are reservoir hosts for Rickettsia helvetica and potentially carry flea-borne Rickettsia species.

    Sprong, H.; Wielinga, P.R.; Fonville, M.; Reusken, C.; Brandenburg, A.H.; Borgsteede, F.H.M.


    Background - Hard ticks have been identified as important vectors of rickettsiae causing the spotted fever syndrome. Tick-borne rickettsiae are considered to be emerging, but only limited data are available about their presence in Western Europe, their natural life cycle and their reservoir hosts.

  15. Spanish participation in the Conference on Security and Cooperation in Europe (CSCE: contributions to the Helsinki Final Act | La participación española en la Conferencia para la Seguridad y la Cooperación en Europa (CSCE: aportaciones al Acta Final de Helsinki

    Ana Capilla Casco


    Full Text Available The Conference on Security and Cooperation in Europe announcement provided Francoist Spain an excellent opportunity to join a multilateral forum aiming to promote security in Europe as well as a détente between the West and the Soviet Union. Spanish diplomacy, despite the relative international isolation of the country and the limits derived from the authoritarian nature of the Regime, designed a negotiation strategy contributing to gaining visibility and providing valuable contributions to the Final Act, such as the incorporation of the text on Mediterranean security. They also reached a wording of the Act principles agreeable to Spain’s interest and to the progress made in United Nations. On the basis of the analysis of the Spanish delegation reports, this article studies both the lights of the work done in Helsinki and Geneva and its shades, the latter being identified with the red lines established by the Francoist Regime. In terms of human rights and especially regarding free circulation and exchange of information. | La convocatoria de la Conferencia para la Seguridad y la Cooperación en Europa brindó una ocasión excelente a la España franquista para poder participar en un foro multilateral destinado a promover la seguridad en Europa y la distensión entre Occidente y la Unión Soviética. La diplomacia española, pese al relativo aislamiento al que seguía sometido el país y las limitaciones que se derivaban de la naturaleza autoritaria del Régimen, trazó una estrategia negociadora que le permitió ganar visibilidad y realizar aportaciones destacadas al Acta Final, como la incorporación del texto sobre la seguridad en el Mediterráneo. Del mismo modo, logró que la redacción de los principios del Acta fuera conforme a los intereses de España y se preservaran los logros alcanzados en Naciones Unidas. Este artículo tiene por objeto estudiar, a partir del análisis de los informes redactados por la propia delegación espa

  16. Imidazopyridine-based inhibitors of glycogen synthase kinase 3: synthesis and evaluation of amide isostere replacements of the carboxamide scaffold.

    Yngve, Ulrika; Söderman, Peter; Svensson, Mats; Rosqvist, Susanne; Arvidsson, Per I


    In this study, we explored the effect of bioisostere replacement in a series of glycogen synthase kinase 3 (GSK3) inhibitors based on the imidazopyridine core. The synthesis and biological evaluation of a number of novel sulfonamide, 1,2,4-oxadiazole, and thiazole derivates as amide bioisosteres, as well as a computational rationalization of the obtained results are reported. Copyright © 2012 Verlag Helvetica Chimica Acta AG, Zürich.

  17. Die Afrikaans van die bybelvertaling van 1933 1 | Steyn | Acta ...

    The first translators of the Bible had to start their work before the standardisation of Afrikaans. This article firstly explores the difficulties encountered by the Bible translators in breaking with the language of the Statenbijbel. Secondly, it is indicated how translators were able to utilise the insights of linguists and language ...

  18. Radical Orthodoxy - Its ecumenical vision | Ward | Acta Theologica

    The first book in the Series Radical Orthodoxy (RO) was not meant to be programmatic or set out to change the direction of modern theology. There are certain shared sensibilities among its authors and, principally, an ecumenical vision. This article sketches the nature of that ecumenical vision that begins with the way in ...

  19. Narrative preaching - yet another perspective | Van Rensburg | Acta ...

    The theme of narrative preaching has been widely discussed for more than a decade. However, only recently did the interest in this form of communication of the gospel of Jesus Christ become apparent within the congregational context. Ministers increasingly find it necessary to adopt a new approach in preaching.

  20. Open-Ended Narrative and Moral Formation | Klaasen | Acta ...

    The PDF file you selected should load here if your Web browser has a PDF reader plug-in installed (for example, a recent version of Adobe Acrobat Reader). If you would like more information about how to print, save, and work with PDFs, Highwire Press provides a helpful Frequently Asked Questions about PDFs.

  1. Narrative temporality and Johannine symbolism: research | Ito | Acta ...

    ? To investigate this is the purpose of this article. The notion of narrative temporality is not new in the study of Biblical texts. However, there have not been many studies which make this notion their main thrust. Rather, generally speaking, it has ...

  2. The illnesses of Herod the Great | Retief | Acta Theologica

    Herod the Great, Idumean by birth, was king of the Jews from 40BC to AD 4. An able statesman, builder and warrior, he ruthlessly stamped out all perceived opposition to his rule. His last decade was characterised by vicious strife within his family and progressive ill health. We review the nature of his illnesses and suggest ...

  3. Acta Theologica 2005: 1 RESENSIES/REVIEWS Trouble in the ...

    Bridges,. Presbyterian Leaders in 19th Century Australia, Melbourne 1993, p.19.) In .... last words. Added ..... But the author calls our attention to the shift from the old con- fessional ... A broad theme such as 2000 years of Christianity requires a selective approach ..... Such fees may be recouped from earnings on research.

  4. Towards a Spirituality of Peace | De Villiers | Acta Theologica

    This article contributes towards designing a Spirituality of Peace within Spirituality as a discipline. It first analyses the increasing attention to violence and peace generally and within religious contexts specifically. It then critically evaluates some approaches that view violence and peace as moral issues and shows how these ...

  5. Gelukkig hij die uw kinderen zal grijpen' | Peels | Acta Theologica

    Happy is he who seizes your infants…. Hermeneutical and biblical-theological positioning of the Old Testament imprecations. The Old Testament contains many prayers for the shaming, punishment or destruction of the godless, especially in the Psalms. This imprecatory prayer, which still forms one of the most troublesome ...

  6. Thomas Aquinas: On Law, Tyranny and Resistance | Swartz | Acta ...

    Thomas Aquinas's notion on law, tyranny and resistance served as a limitation on governmental powers. When those who bear the law command things which exceed the competence of such authority, the subject is free to obey or disobey. The function of the law culminates in two maxims: quantum ad vim coactivam legis ...

  7. Tumours and cancers in Graeco-Roman times | Retief | Acta ...

    In Hippocratic literature tumours were mainly classified as karkinômata, phumata and oidêmata. Phumata included a large variety of tumours, inflammatory and neoplastic in origin, and mostly benign (in modern terms), whilst oidêmata were soft, painless tumours and even included generalised oedema (dropsy). Although ...

  8. Godsdiens: Middel tot verslawing of tot heling? | Coetzer | Acta ...

    There are two sides to religion, on the one hand the threat that implies emotional pain and addiction, on the other hand the healing and liberating effect of a balanced and healthy religion. In this article the focus is on the former. Factors which render people vulnerable to spiritual addiction are put on the table. Similarities ...

  9. Paul, military imagery and social disadvantage | Punt | Acta ...

    In the past, attention for the social position or standing of the early Jesus followers was overrun by concerns for the theological and religious dimensions of those communities. The role of the Roman Empire and the impact of its military forces on the lives of people have generated even less attention. Paul's use of military ...

  10. Jesus, history and the gospels: research | Moyise | Acta Theologica

    This article considers the reasons why modern scholars have felt the need to go behind the four Gospels and search for the historical Jesus. After a short discussion on methodology, especially the criteria used to detect the earliest and most reliable traditions about Jesus, a number of recent proposals are discussed: Jesus ...

  11. Contours of Biblical spirituality as a discipline | Welzen | Acta ...

    ... divine human relational process. A dialogue of spirituality and exegesis is needed. For doing research a threefold competence is needed: in exegesis, in spirituality and in the integration of these two. The final section is about intertextuality. Intertextuality may help to understand the spiritual process in reading biblical texts.

  12. Interview with Piet J. Naudé | Laubscher | Acta Theologica

    ... The Netherlands. His thesis explored the relation between theory and practice in Latin-American Liberation Theologies and the work of Johann Baptist Metz. As Humboldt scholar, he later built a special academic relation with Michael Welker in Heidelberg (Germany) and with the Centre for Theological Inquiry at (USA).

  13. Egyptian personal piety and Israel's wisdom literature | Fischer | Acta ...

    This article evaluates the movement of Egyptian personal piety and its relation to Israelite wisdom texts. Hymns and prayers of personal piety developed in the New Kingdom at the same time as "heretic" Harpers' songs and love songs. The personal piety affected also the genre of instructions. The instruction of Amenemope ...

  14. A new framework for Bible translation | Wilt | Acta Theologica

    ... as well as translators and choosing a particular translation approach in terms of mutually agreed upon goals. The Bible translation process may involve not just producing a text to represent the sacred text, but also supplementary texts to enhance understanding and appreciation of both the translation and the translated.

  15. The language ecology of a new Afrikaans Bible | Ponelis | Acta ...

    Three sets of codes are germane to a current Afrikaans Bible translation: Dutch, English and varieties of Afrikaans, especially Standard Afrikaans. Dutch was established as a local language of culture in the Dutch era from 1652 to 1806. The sweeping transformation of Cape society by British colonial rule gave great impetus ...

  16. A new leadership for a new ecclesiology | Mothoagae | Acta ...

    While many berate the poor level of leadership in the Church, it is noticeable that the same complaint is made about leadership in the corporate world. It is the authors' contention that the new ecclesiology that has been spoken and written about during the past decades cannot be implemented until there is a change in the ...

  17. Persecution in the book of Revelation | De Villiers | Acta Theologica

    In this article attention will be given to scholarly interpretations of persecution in Revelation with special attention to their theoretical, hermeneutical and theological implications. After an introductory discussion of the traditional interpretation of a ";real"; persecution in a Domitianic setting, attention will be given to the recent ...

  18. Poverty Relief or Poverty Eradication? | Kritzinger | Acta Theologica

    The author challenges the reader to make two mindshifts: from a focus on poverty relief to an emphasis on poverty eradication; and from viewing the poor as the objects of poverty alleviation to accepting them as the subjects of poverty eradication. The case is argued and a practical approach towards poverty eradication is ...

  19. Snake and staff symbolism in healing | Retief | Acta Theologica

    Since time immemorial the snake has been venerated as an enigmatic creature with supernatural powers. As a snake and staff symbol it is also traditionally associated with the healing arts, either as the single-snake attribute of Asclepius, or as the doublesnake attribute of Hermes. In this article the mythological basis for this ...

  20. Etiese Besluitneming Volgens 1 Johannes | van der Watt | Acta ... · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use · Contact AJOL · News. OTHER RESOURCES... for Researchers · for Journals · for Authors · for Policy Makers ...

  1. Kom ons skryf 'n Psalm! | Snyman | Acta Theologica

    psalms of the setting in life (Sitz im Leben) of the psalms. Due to the personal nature of the psalms, the exact setting in life was even deliberately obscured. This should caution modern day researchers of the canonical Psalms to be mindful of the fact ...

  2. Power and authority in Matthew's gospel | Viljoen | Acta Theologica

    Besides the strenuous relation of Matthew's community with non-Christian kinfolk, his text also reveals an underlying conflict with Roman Imperial ideology. Herod, Antipas and Pilate specifically impersonate this foreign domination. Apparently these figures have unlimited power which leaves Jesus and his followers as ...

  3. Skrif en Kerkorder/Scripture and church order | Celliers | Acta ...

    This enables the congregation to adhere to its calling for obedience, love, and witness, so that the church can continue to exist. The outlines of the nature and order of the church should be addressed in all church orders to avoid pragmatism and arbitrariness on the one hand, and to create space for the various demands of ...

  4. Lead poisoning in ancient Rome | Retief | Acta Theologica

    Lead was known to the ancients from at least the 4th millennium BC, but its use increased markedly during Roman times, to the extent that it became a health hazard. Mines and foundry furnaces caused air pollution; lead was extensively used in plumbing; domestic utensils were made of lead and pewter, and lead salts ...

  5. Sociedad de Estudios de Patología Quirúrgica de la Facultad de Medicina de Bogotá: estatutos: Estudio e Investigación. Reglamento: Tolerancia por las ideas ajenas (Acta de los días 4 y 11 de junio

    Roberto N. Ezpeleta H.


    Full Text Available El día 4 de junio a las 10 de la mañana se reunió la "Sociedad de Estudios de Patología Quirúrgica" en el salón de proyecciones adjunto al Laboratorio de Rayos X del Hospital. Presidió la sesión el Profesor Jorge E. Cavelier. Asistieron a ella los Profesores Corpas y Salgar, y los doctores Herrera Salgar y Jiménez. Suárez Una vez leída el acta de la sesión anterior, el doctor Herrera Salgar presentó un curioso caso sobre apéndice doble, dando una relación de él y mostrando unas placas anatomo-patológicas muy demostrativas. En seguida tomó la palabra el Profesor Corpas quien se refirió al caso presentado por el doctor Herrera Salgar, caso que, dijo, era tanto más interesante cuanto que se refería a una apendicitis crónica, pues muchas veces se presentaban falsos apéndices dobles. en las apendicitis agudas en las que el apéndice sufre a veces una especie de estrangulación cuya parte libre es injertada en el ciego semejando un apéndice doble. Dijo que el apéndice tenía por objeto suministrar una hormona cuyo papel es activar el peristaltismo intestinal, lo cual se puede comprobar por la constipación habitual de que son víctimas los apendicectomizados. Hizo referencias a las anomalías en la especie humana, como manifestaciones de evolución regresiva, y mostró cómo en el caso particular de apéndice doble éste estan frecuente en los hervíboros.

  6. Secondary metabolites from Pinus mugo Turra subsp. mugo growing in the Majella National Park (Central Apennines, Italy).

    Venditti, Alessandro; Serrilli, Anna Maria; Vittori, Sauro; Papa, Fabrizio; Maggi, Filippo; Di Cecco, Mirella; Ciaschetti, Gianpiero; Bruno, Maurizio; Rosselli, Sergio; Bianco, Amandodoriano


    In this study, we examined the composition regarding secondary metabolites of P. mugo Turra ssp. mugo growing in the protected area of Majella National Park, which is the southernmost station of the habitat of this species. Both the nonpolar and polar fractions were considered. In particular, the essential-oil composition showed a high variety of compounds, and 109 compounds were detected, and 101 were identified, among which abietane-type compounds have a taxonomic relevance. Abietanes were also isolated from the polar fraction, together with an acylated flavonol and a remarkably high amount of shikimic acid. Copyright © 2013 Verlag Helvetica Chimica Acta AG, Zürich.

  7. Synthesis and immunostimulating properties of novel adamant-1-yl tripeptides.

    Ribić, Rosana; Habjanec, Lidija; Vranešić, Branka; Frkanec, Ruža; Tomić, Srđanka


    The aim of this work was to prepare L- and D-(adamant-1-yl)-Gly-L-Ala-D-isoGln peptides in order to study their adjuvant (immunostimulating) activities. Adjuvant activity of adamant-1-yl tripeptides was tested in the mouse model using ovalbumin as an antigen and in comparison to the peptidoglycan monomer (PGM; β-D-GlcNAc-(1→4)-D-MurNAc-L-Ala-D-isoGln-mesoDAP(εNH(2) )-D-Ala-D-Ala) and structurally related adamant-2-yl tripeptides. Copyright © 2012 Verlag Helvetica Chimica Acta AG, Zürich.

  8. Indole Alkaloids from the Sea Anemone Heteractis aurora and Homarine from Octopus cyanea.

    Shaker, Kamel H; Göhl, Matthias; Müller, Tobias; Seifert, Karlheinz


    The two new indole alkaloids 2-amino-1,5-dihydro-5-(1H-indol-3-ylmethyl)-4H-imidazol-4-one (1), 2-amino-5-[(6-bromo-1H-indol-3-yl)methyl]-3,5-dihydro-3-methyl-4H-imidazol-4-one (2), and auramine (3) have been isolated from the sea anemone Heteractis aurora. Both indole alkaloids were synthesized for the confirmation of the structures. Homarine (4), along with uracil (5), hypoxanthine (6), and inosine (7) have been obtained from Octopus cyanea. Copyright © 2015 Verlag Helvetica Chimica Acta AG, Zürich.

  9. Enantioselectivity of the bioconversion of chiral citronellal during the inhibition of wheat seeds germination.

    Cavalieri, Andrea; Fischer, Ravit; Larkov, Olga; Dudai, Nativ


    Citronellal is one of the most prominent monoterpenes present in many essential oils. Low persistence of essential oils as bioherbicides has often been addressed because of the high volatility of these compounds. Bioconversion of citronellal by wheat seeds releases less aggressive and injurious compounds as demonstrated by their diminished germination. We demonstrated that optically pure citronellal enantiomers were reduced to optically pure citronellol enantiomers with retention of the configuration both in isolated wheat embryos and endosperms. Our findings reveal the potential of essential oils as allelopathic agents providing an insight into their mechanism of action and persistence. Copyright © 2014 Verlag Helvetica Chimica Acta AG, Zürich.

  10. Allelopathic potential of Rapanea umbellata leaf extracts.

    Novaes, Paula; Imatomi, Maristela; Varela, Rosa M; Molinillo, José M G; Lacret, Rodney; Gualtieri, Sonia C J; Macías, Francisco A


    The stressful conditions associated with the Brazilian savanna (Cerrado) environment were supposed to favor higher levels of allelochemicals in Rapanea umbellata from this ecosystem. The allelopathic potential of R. umbellata leaf extracts was studied using the etiolated wheat coleoptile and standard phytotoxicity bioassays. The most active extract was selected to perform a bioassay-guided isolation, which allowed identifying lutein (1) and (-)-catechin (2) as potential allelochemicals. Finally, the general bioactivity of the two compounds was studied, which indicated that the presence of 1 might be part of the defense mechanisms of this plant. Copyright © 2013 Verlag Helvetica Chimica Acta AG, Zürich.

  11. “One in christ”: Fedsem spiritualities of solidarity | Duncan | Acta ...

    The spiritual life of the seminary, manifested most clearly in its worship life, became its source of strength and sustained its mission and vision: to be and yet, to become “One in Christ”. This was conveyed by means of various forms of denominational and ecumenical solidarity as an expression of Christian love.

  12. Klaagliedere 3:42: vergifnis of nie-vergifnis? | O'Kennedy | Acta ...

    Lamentations 3 speaks about punishment, but not rejection or unwillingness to forgive. The worshipper in verse 42 confronts God with his real self: He is supposed to forgive. In the rest of chapter 3 we find reminders of God's forgiving heart: mercy and compassion (vv. 22, 32); faithfulness (v. 23); kindness (vv. 25, 26, 27); ...

  13. “Showing respect” in bible translation | van der Spuy | Acta Theologica

    This article focuses on the way respect is shown by using 2nd person personal pronouns in languages that distinguish between you plural (you all), you honorific (polite) and you singular (familiar) forms. It discusses the likely influence of the well known Russian Synodal Translation on other translations in the former Soviet ...

  14. Turismo Musical y Festivales. Actas del I Congreso Internacional de Turismo Musical y Festivales

    Martín Gómez-Ullate García de León; Pilar Barrios Manzano; Juana Gómez Pérez


    The University of Extremadura hosted the 1st International Conference in Musical Tourism and Festivals 17-18 December 2015. This conference was a space for exchange between stakeholders and academics the musical tourism and festivals fields to learn from other areas and sectors; it will include keynotes, stakeholder-led discussion groups and parallel papers & posters considering and showcasing the delivery and assessment of engaged and impactful research. Spain and Portugal hold great pot...

  15. Digitalization of "Acta Stomatologica Croatica" Journal (1966;1 - 1999;33).

    Borić, Vesna


    Modern documents, scientific articles and books are primarily issued in electronic form and their availability depends on the publisher's, or the document owner's, business ethics. The primary purpose of publishing a scientific article is to communicate with the scientific and professional community; therefore, the published article has to be available worldwide. The question is: Who really needs scientific papers from the 1960's? In cases of brilliant and bold visionaries, new concepts and scientific discoveries often come before their time; hence they have to be "reinvented" decades later. Besides, the scientists of today can enter the spiritual spheres of their professional ancestors and give respect to their legacy.
We have processed more than 1 200 articles published by 1999 and entered more than
6 000 names and surnames of authors.

  16. In search of the original text in Mark 9:38 | Hendriks | Acta Theologica

    The question remains which text appears to be the more original one. Several scholars – such as Vaganay, Duplacy, Amphoux, and others – in search of the original text of Mark – opt for a so called Western text, the main stream still prefers the Neutral text of Westcott and Hort. A text-critical analysis of Mark 9:38 may provide ...

  17. Actas III Jornadas de Propiedad Intelectual. Los soportes en los que se recogen tangibles e intangibles.

    Domenech Martínez, Gloria


    En estos tiempos tan convulsos que nos ha tocado vivir, es necesario proteger los derechos de propiedad intelectual para fomentar el crecimiento económico, la innovación y la creatividad. Las medidas destinadas a salvaguardar los derechos de propiedad intelectual (DPI) y a luchar contra la falsificación y la piratería en el mercado interior abarcan tanto el ámbito penal como el civil, sin olvidar el ámbito mercantil, jurisdicción especial en el campo civil. Sin relegar la pe...

  18. La dinámica participativa en las actas de reuniones del CONEI

    Lilia Calderón Almerco


    Full Text Available The dynamism of participation in the minutes of the CONEI meetings This is a discussion about the results of a documentary research about the participative dynamics into the minutes of the CONEI (Consejo Educativo Institucional meetings of four public schools from Lima. The qualitative analysis of the minutes reveals that the participation characterizes for being formal, bureaucratic, unidirectional and conflicted; that is focused in the administrative and economic issues of the educational management. The discourse expresses an ideal vision about participation but negative about conflict. Also, the participation in the meeting is considered like being in the meeting, and the leadership of the principal and the teachers stands out, however, the students and parents are excluded or autoexcluded.

  19. Rethinking the demarcation of Malachi 2:17-3:5 | Snyman | Acta ...

    emarcating a unit remains important for the interpretation and understanding of the particular unit in a (Biblical) book. In the case of the book of Malachi, the majority of scholars adhere to the traditional demarcation of the fourth unit in the book of Malachi (2:17-3:5). Closer investigation reveals that the matter is not as settled ...

  20. Tax Evasion and the Impact on Economic Growth Acta Universitatis Danubius. OEconomica

    Shkendije Demalijaj Ukaj


    Full Text Available The level of taxation is very important for the development of current and future of a country and fiscal policy should always be considered as an important factor in the behavior of participants and their ability to tax evasion and informality. Government fiscal policies can trigger tax increase under pressure, especially in situations such as economic crisis, inflation, unemployment, instability, when the burden of this obligation grows, its effects are considered to take them to tax evasion and informality (Dragomir. et al. 2011. However, these reasons do not relate to all the great presence of this phenomenon in Kosovo, taking into account the recent economic crisis has not reflected in the economy of Kosovo and the Kosovo tax burden is among the lowest in the region, but leading cause of tax evasion and informality can be considered above the corruption of public administration officials including tax and customs officials, insufficient staff for his fighting, weak rule of law, as well as lower fiscal culture for paying taxes. For this reason the scope of this paper will be the theoretical treatment of the informal economy and tax evasion in view of tax avoidance, meaning, characteristics and their effects on the economy and possible recommendations on these viewpoints.

  1. “Bond of love”: The action of the spirit | Williams | Acta Theologica

    The ancient idea, seen especially in Augustine, is that the main activity of the Spirit is that of providing relationship, as the “bond of love”; this provides a key concept which undergirds the work of the Spirit in creation, redemption, sanctification and empowering. It is hoped that increased understanding of the work of the Spirit ...

  2. Actas I Simposio Iberoamericano de Ecología Reproductiva, Reclutamiento y Pesquerías

    Saborido-Rey, Fran; Macchi, Gustavo; Murua, Hilario


    El I Simposio Iberoamericano de Ecología Reproductiva, Reclutamiento y Pesquerías (Sibecorp) surge en respuesta a la inquietud de investigadores de Iberoamérica por fomentar la colaboración entre países de uno y otro lado del Atlántico, en el reconocimiento de que la pesca es un recurso económico vital en Latinoamérica, España y Portugal. Son numerosos los grupos de investigación que desarrollan su labor en el campo de la ecología pesquera y que profundizan en el concepto de sostenibili...

  3. The interpretation and translation of galatians 5:12 | Tolmie | Acta ...

    As is evident from commentaries on Galatians and from various English translations, scholars do not agree on the meaning, rhetorical labelling and translation of the wish expressed by Paul in Galatians 5:12 ( [Ofelon kai; ajpokovyontai oiJ ajnastatou` nte” uJma`”). In this article various interpretations of this verse are ...

  4. Respek vir die liturgiese teks: J. Calvyn en J.S. Bach | Schulze | Acta ...

    Despite obvious differences in terms of historical and theological aspects between Calvin and Bach, both share a respect for the priority of the Biblical text in worship.The anomaly between Calvin's engagement in the versification of the Psalter and Bach's preference for the literal (rather than a versified) use of the Biblical ...

  5. Actas do 1º Encontro do Mel das Arribas do Douro - ArribasMel 2004

    Marcos, Adérito


    1º Encontro do Mel das Arribas do Douro - ArribasMel 2004, Solar dos Marcos, Bemposta, Mogadouro, 27 Março 2004 Livro de resumos do 1º Encontro do Mel das Arribas do Douro - ArribasMel 2004, realizado no Solar dos Marcos, Bemposta, Mogadouro, 27 de Março 2004.

  6. ACTA-EVER lecture 2007 - The retinal pigment epithelium: friend or foe?

    La Cour, Morten


    proliferating RPE cells. By means of 5-bromo-2-deoxyuridine (BrdU) labelling, we studied the proliferation of RPE cells in the porcine eye after experimental posterior pole injury. Surprisingly, we found that only the peripheral RPE cells incorporated the BrdU label, indicating that central injury elicits...... for long contact times between therapeutic, and non-toxic, concentrations of 5-FU and the RPE Udgivelsesdato: 2008/9...

  7. Twentieth-century English Bible translations | Naudé | Acta Theologica

    The twentieth century has emerged as a major period of Bible translations and publications. The article explores both the cultural and social circumstances under which the English Bible translations of the twentieth century were produced and aspects relating to the translation process and reception. It offers insights into the ...

  8. Acta Theologica 2015: 2 207 M. Nel Identity-driven churches: Who ...

    and systematic study that produces a wealth of contextual biblical ideas concerning ... debates and empirical data that have emerged and are still emerging concerning ... conversation lies a challenge: to recover and deepen the church's.

  9. Tax Evasion and the Impact on Economic Growth Acta Universitatis Danubius. OEconomica

    Shkendije Demalijaj Ukaj


    The level of taxation is very important for the development of current and future of a country and fiscal policy should always be considered as an important factor in the behavior of participants and their ability to tax evasion and informality. Government fiscal policies can trigger tax increase under pressure, especially in situations such as economic crisis, inflation, unemployment, instability, when the burden of this obligation grows, its effects are considered to take them t...

  10. Acta Oncologica Lecture. Gastrointestinal consequences of cancer treatment and the wider context: a bad gut feeling.

    Muls, Ann Cecile


    The percentage of people living with a diagnosis of cancer is rising globally. Between 20% and 25% of people treated for cancer experience a consequence of cancer which has an adverse impact on the quality of their life. Gastrointestinal (GI) symptoms are the most common of all consequences of cancer treatment and have the greatest impact on daily activity. PATHOPHYSIOLOGY OF LONG-TERM BOWEL DAMAGE AFTER PELVIC RADIOTHERAPY: Long-term damage to the bowel after radiotherapy is mediated by ischaemic changes and fibrosis. Each fraction of radiotherapy causes a series of repetitive injuries to the intestinal tissue resulting in an altered healing process, which affects the integrity of the repair and changes the architecture of the bowel wall. THE NATURE OF GI SYMPTOMS THAT DEVELOP: Patient-reported outcome measures show that diarrhoea, urgency, increased bowel frequency, tenesmus and flatulence are the five most prevalent GI symptoms with a moderate or severe impact on patients' daily lives after treatment with pelvic radiotherapy. Many patients also experience fatigue, urinary problems and have sexual concerns. SYSTEMATIC ASSESSMENT AND MANAGEMENT: The complex nature of those symptoms warrants systematic assessment and management. The use of a tested algorithm can assist in achieving this. The most common contributing factors to ongoing bowel problems after pelvic radiotherapy are small intestinal bacterial overgrowth, bile acid malabsorption, pancreatic insufficiency, rectal bleeding and its impact on bone health. Symptom burden, socio-psychosocial impact, memory and cognitive function, fatigue, urinary problems and sexual concerns need to be taken into account when thinking about consequences of cancer treatment. As our understanding of consequences of cancer treatments continues to emerge and encompass a wide variety of specialties, a holistic, multifaceted and multidisciplinary approach is required to manage those consequences long-term.

  11. Causes of death among the Caesars (27 BC-AD 476) | Retief | Acta ...

    The Roman Empire was ruled by 77 emperors between 27 BC and AD 476 (503 years); 18 (23,4%) of them held sway during the Early Empire (27 BC–AD 193, 220 years), and 59 (76,6%) during the Late Empire (193-476, 283 years). On the average emperors in the Early Empire ruled for a longer period (12,7 years as ...

  12. Chemical composition and antimicrobial activity of the essential oil of endemic Dalmatian black pine (Pinus nigra ssp. dalmatica).

    Politeo, Olivera; Skocibusic, Mirjana; Maravic, Ana; Ruscic, Mirko; Milos, Mladen


    The chemical composition and the antimicrobial activity of the essential oil isolated from the needles of endemic Dalmatian black pine (Pinus nigra ssp. dalmatica) from Croatia were investigated. The chemical composition of the essential oil was determined by GC and GC/MS analyses, and the main compounds identified were α-pinene, β-pinene, germacrene D, and β-caryophyllene. Disc-diffusion and broth-microdilution assays were used for the in vitro antimicrobial screening. The Dalmatian black pine essential oil exhibited a great potential of antibacterial activity against Gram-positive bacteria (MIC=0.03-0.50% (v/v)) and a less pronounced activity against Gram-negative bacteria (MIC=0.12-3.2% (v/v)). The volatile compounds also inhibited the growth of all fungi tested, including yeast. Copyright © 2011 Verlag Helvetica Chimica Acta AG, Zürich.

  13. The Essential Oil Compositions of Ocimum basilicum from Three Different Regions: Nepal, Tajikistan, and Yemen.

    Sharopov, Farukh S; Satyal, Prabodh; Ali, Nasser A Awadh; Pokharel, Suraj; Zhang, Hanjing; Wink, Michael; Kukaniev, Muhammadsho A; Setzer, William N


    The aerial parts of Ocimum basilicum L. were collected from four different geographical locations, Sindhuli and Biratnagar (Nepal), Chormaghzak village (Tajikistan), and Sana'a (Yemen). The essential oils were obtained by hydrodistillation and analyzed by gas chromatography/mass spectrometry. A cluster analysis of 179 essential oil compositions revealed six major chemotypes: Linalool, eugenol, estragole, methyl eugenol, 1,8-cineole, and geraniol. All four of the basil oils in this study were of the linalool-rich variety. Some of the basil oils were screened for bioactivity including antimicrobial, cytotoxicity in human cancer cells, brine shrimp lethality, nematicidal, larvicidal, insecticidal, and antioxidant. The basil oils in this study were not notably antibacterial, cytotoxic, antioxidant, nor nematicidal, but were active in the brine shrimp lethality test, and did show larvicidal and insecticidal activities. Copyright © 2016 Verlag Helvetica Chimica Acta AG, Zürich.

  14. Dehalogenation Activity of Selected Fungi Toward δ-Iodo-γ-Lactone Derived from trans,trans-Farnesol.

    Gliszczyńska, Anna; Gładkowski, Witold; Świtalska, Marta; Wietrzyk, Joanna; Szumny, Antoni; Gębarowska, Elżbieta; Wawrzeńczyk, Czesław


    Time-course of biotransformation of racemic trans-4-((E)-4',8'-dimethylnona-3',7'-dien-1-yl)-5-iodomethyl-4-methyldihydrofuran-2-one (1) in fungal and yeast cultures was investigated. In these conditions, the substrate 1 was enantioselectively dehalogenated yielding 4-((E)-4',8'-dimethylnona-3',7'-dien-1-yl)-4-methyl-5-methylenedihydrofuran-2-one (2) and its structure was established based on the spectroscopic data. The most effective biocatalyst used was Didymosphaeria igniaria, which catalyzed the process with highest rate and enantioselectivity (ee of product = 76%). The antiproliferative activity of δ-iodo-γ-lactone 1, product of its biotransformation 2, and starting substrate (farnesol) were evaluated toward two cancer cell lines: A549 (human lung adenocarcinoma) and HL-60 (human promyelocytic leukemia). © 2016 Verlag Helvetica Chimica Acta AG, Zürich.

  15. Botanical, Phytochemical, and Anticancer Properties of the Eucalyptus Species.

    Vuong, Quan V; Chalmers, Anita C; Jyoti Bhuyan, Deep; Bowyer, Michael C; Scarlett, Christopher J


    The genus Eucalyptus (Myrtaceae) is mainly native to Australia; however, some species are now distributed globally. Eucalyptus has been used in indigenous Australian medicines for the treatment of a range of aliments including colds, flu, fever, muscular aches, sores, internal pains, and inflammation. Eucalyptus oils containing volatile compounds have been widely used in the pharmaceutical and cosmetics industries for a multitude of purposes. In addition, Eucalyptus extracts containing nonvolatile compounds are also an important source of key bioactive compounds, and several studies have linked Eucalyptus extracts with anticancer properties. With the increasing research interest in Eucalyptus and its health properties, this review briefly outlines the botanical features of Eucalyptus, discusses its traditional use as medicine, and comprehensively reviews its phytochemical and anticancer properties and, finally, proposes trends for future studies. Copyright © 2015 Verlag Helvetica Chimica Acta AG, Zürich.

  16. Four New Flavonoids with α-Glucosidase Inhibitory Activities from Morus alba var. tatarica.

    Zhang, Ya-Long; Luo, Jian-Guang; Wan, Chuan-Xing; Zhou, Zhong-Bo; Kong, Ling-Yi


    Four new flavonoids, mortatarins A-D (1-4, resp.), along with eight known flavonoids (5-12) were isolated from the root bark of Morus alba var. tatarica. Their structures were established on the basis of spectroscopic data analysis, and the absolute configuration of 4 was determined by analysis of its CD spectrum. All isolates were tested for inhibitory activities against α-glucosidase. Compounds 4, 7, and 8 exhibited a significant degree of inhibition with IC50 values of 5.0 ± 0.3, 7.5 ± 0.5, and 5.9 ± 0.2 μM, respectively. Copyright © 2015 Verlag Helvetica Chimica Acta AG, Zürich.

  17. Volatile oils from the aerial parts of Eremophila maculata and their antimicrobial activity.

    Youssef, Fadia S; Hamoud, Razan; Ashour, Mohamed L; Singab, Abdel Nasser; Wink, Michael


    The essential oils isolated from the fresh flowers, fresh leaves, and both fresh and air-dried stems of Eremophila maculata (Scrophulariaceae) were characterized by GC-FID and GC/MS analyses. Sabinene was the major component in most of the oils, followed by limonene, α-pinene, benzaldehyde, (Z)-β-ocimene, and spathulenol. The leaf and flower essential oils showed antibacterial and antifungal activity against five Gram-positive and four Gram-negative bacterial strains, multi-resistant clinical isolates from patients, i.e., methicillin-resistant Staphylococcus aureus (MRSA), as well as two yeasts. Minimum inhibitory concentrations (MICs) and minimum microbicidal concentrations (MMCs) were between 0.25 and 4 mg/ml. Copyright © 2014 Verlag Helvetica Chimica Acta AG, Zürich.

  18. New isocoumarins from a cold-adapted fungal strain mucor sp. and their developmental toxicity to zebrafish embryos.

    Feng, Chun-Chi; Chen, Guo-Dong; Zhao, Yan-Qiu; Xin, Sheng-Chang; Li, Song; Tang, Jin-Shan; Li, Xiao-Xia; Hu, Dan; Liu, Xing-Zhong; Gao, Hao


    Three new isocoumarin derivatives, mucorisocoumarins A-C (1-3, resp.), together with seven known compounds, 4-10, were isolated from the cold-adapted fungal strain Mucor sp. (No. XJ07027-5). The structures of the new compounds were identified by detailed IR, MS, and 1D- and 2D-NMR analyses. It was noteworthy that compounds 1, 2, 4, and 5 were successfully resolved by chiral HPLC, indicating that 1-7 should exist as enantiomers. In an embryonic developmental toxicity assay using a zebrafish model, compound 3 produced developmental abnormalities in the zebrafish embryos. This is the first report of isocoumarins with developmental toxicity to zebrafish embryos. Copyright © 2014 Verlag Helvetica Chimica Acta AG, Zürich.

  19. Contribution to a Taxonomic Revision of the Sicilian Helichrysum Taxa by PCA Analysis of Their Essential-Oil Compositions.

    Maggio, Antonella; Bruno, Maurizio; Guarino, Riccardo; Senatore, Felice; Ilardi, Vincenzo


    The chemical profile of the essential oils in ten populations of the genus Helichrysum Mill. (Asteraceae), collected in the loci classici of the nomenclatural types of the taxa endemic to Sicily, were analyzed. Our results confirm that the analysis of secondary metabolites can be used to fingerprint wild populations of Helichrysum, the chemical profiles being coherent with the systematic arrangement of the investigated populations in three main clusters, referring to the aggregates of H. stoechas, H. rupestre, and H. italicum, all belonging to the section Stoechadina. The correct nomenclatural designation of the investigated populations is discussed and the following two new combinations are proposed: Helichrysum preslianum subsp. compactum (Guss.) Maggio, Bruno, Guarino, Senatore & Ilardi and Helichrysum panormitanum subsp. latifolium Maggio, Bruno, Guarino, Senatore & Ilardi. Copyright © 2016 Verlag Helvetica Chimica Acta AG, Zürich.

  20. The Chemical Diversity of Lantana camara: Analyses of Essential Oil Samples from Cuba, Nepal, and Yemen.

    Satyal, Prabodh; Crouch, Rebecca A; Monzote, Lianet; Cos, Paul; Awadh Ali, Nasser A; Alhaj, Mehdi A; Setzer, William N


    The aerial parts of Lantana camara L. were collected from three different geographical locations: Artemisa (Cuba), Biratnagar (Nepal), and Sana'a (Yemen). The essential oils were obtained by hydrodistillation and analyzed by gas chromatography/mass spectrometry. A cluster analysis of 39 L. camara essential oil compositions revealed eight major chemotypes: β-caryophyllene, germacrene D, ar-curcumene/zingiberene, γ-curcumen-15-al/epi-β-bisabolol, (E)-nerolidol, davanone, eugenol/alloaromadendrene, and carvone. The sample from Cuba falls into the group dominated by (E)-nerolidol, the sample from Nepal is a davanone chemotype, and the sample from Yemen belongs to the β-caryophyllene chemotype. The chemical composition of L. camara oil plays a role in the biological activity; the β-caryophyllene and (E)-nerolidol chemotypes showed antimicrobial and cytotoxic activities. © 2016 Verlag Helvetica Chimica Acta AG, Zürich.

  1. Drimane sesquiterpenoids from the Aspergillus oryzae QXPC-4.

    Ren, Ren; Chen, Chao-Jun; Hu, Sha-Sha; Ge, Hui-Ming; Zhu, Wen-Yong; Tan, Ren-Xiang; Jiao, Rui-Hua


    Three new drimane sesquiterpenoids, astellolides C-E (1-3, resp.), four new drimane sesquiterpenoid p-hydroxybenzoates, astellolides F-I (4-7, resp.), together with two known compounds astellolides A and B (8 and 9, resp.), have been isolated from the liquid culture of Aspergillus oryzae (strain No. QXPC-4). Their structures were established by comprehensive analysis of spectroscopic data. The relative and absolute configurations were determined on the basis of NOESY and CD data, together with single-crystal X-ray diffraction analyses of compounds 1-3. The metabolites were evaluated for their cytotoxic activities, however, no compounds showed a significant cytotoxicity against the tested cell lines at a concentration of 20 μM. Copyright © 2015 Verlag Helvetica Chimica Acta AG, Zürich.

  2. Acta Medica Indonesiana - The Indonesian Journal of Internal Medicine 333 Supraclavicular Lymphnodes: Unusual Manifestation of Metastase Adenocarcinoma Colon

    Harijono Achmad


    Full Text Available We report a patient with supraclavicular lymph node metastasis from an undetectable adenocarcinoma of the transverse colon, who presented with cough and was diagnosed with typhoid fever, bronchitis as well as liver metastasis. There were an abdominal fullness, weight loss, constipation, pencil-like stool with mucous and blood, low-grade fever, bone ache, and tea-color urine. The first colonoscopy revealed lymphocytic ileitis and microscopic findings also showed lymphocytic ileitis. Abdominal USG and CT revealed liver metastasis of unknown origin. Based on the clinical sign and symptoms, we suspected that colorectal carcinoma was the primary site. Then, the second colonoscopy was performed and it revealed a small polyp, which was followed with a biopsy and the result supported a well-differentiated colon adenocarcinoma. Similar result was also revealed by the histopathological evaluation. This is an unusual case of liver and supraclavicular lymph node metastasis arising from a small polyp adenocacinoma of the transverse colon. Key words: liver metastase, colorectal carcinoma, lymph node.


    Delgado, Hernán


    Reunidos en la Sede de la Escuela de Nutrición de la Universidad de Costa Rica, el Instituto deNutrición de Centroamérica y Panamá INCAP/OPS con sede en Guatemala y representada por suDirector Dr. Hernán Delgado, y la Vicerrectoría de Investigación de la Universidad de Costa Rica,representada por el Dr. Henning Jensen Pennington, en calidad de entidades fundadoras de la Redde Investigación en Seguridad Alimentaria

  4. Proceedings of the Fourth Session of Radioprotection of the patient; Actas de la 4. Jornada de Proteccion Radiologica al Paciente



    The Radiology Argentine Society and the Radioprotection Argentine Society have organized the 4. Session of the Protection to the Patient, in order to inform to the technical and scientific community about the scopes of the radioprotection to the patient. The principal treated topics were the following: effects of the radiation in radiodiagnostic; radioprotection of the fetus and the pregnancy woman; radioprotection in dental radiology; radiological protection in TAC; radiation doses in radiodiagnostic; treatment of radiation injuries; fatal accidents in radiotherapy. [Spanish] La Sociedad Argentina de Radiologia, y la Sociedad Argentina de Radioproteccion, han organizado la 4ta. Jornada de Proteccion al Paciente, con el objeto de informar a la comunidad cientifico y tecnica sobre los alcances de la radioproteccion al paciente. Los principales temas tratados fueron los siguientes: efectos de la radiacion en radiodiagnostico; radioproteccion del feto y la mujer gestante; radioproteccion en radiologia odontologica; proteccion radioogica en TAC; dosis de radiacion en radiodiagnostico; tratamiento de lesiones por radiacion; accidentes fatales en radioterapia.

  5. Fenomenologia e Ciência. Actas do IVº Congresso Internacional da AFFEN – IIIº Congresso Luso-Brasileiro de Fenomenologia

    Borges-Duarte, Irene; Pardelha, Irene


    Este volume reune os textos apresentados ao IVº Congresso Internacional da AFFEN – IIIº Congresso Luso-Brasileiro de Fenomenologia, em 5 secções: Ciência, Técnica, Psicoterapia fenomenológica, Questões da Fenomenologia Husserliana e Outras fenomenologias. Tendo como temática unificadora «Fenomenologia e Ciência», integram-se trabalhos sobre aplicação da metodologia fenomenológica e hermenêutica às questões da ciência e da técnica, e a âmbitos científicos particulares como a Psicologia, a Soci...

  6. Proceedings CORENDE: Regional congress on nondestructive and structural evaluation; Actas CORENDE: Congreso regional de ensayos no destructivos y estructurales



    Works are presented at the CORENDE: Regional Congress on Nondestructive and Structural Evaluation organized by the National Atomic Energy Commission and the National Technological University (Mendoza). This congress wants to be the forum where people from research, industry and marketing might meet and discuss ideas towards the fostering of these new cultural habits. Papers covering all disciplines contributing to the evaluation of components, systems and structures are welcome: nondestructive evaluation methods and techniques (ultrasound, eddy currents and other electromagnetic methods, acoustic emission, radiography, thermography, leak testing, dye-penetrants, visual inspection, etc.), personnel certification, welding inspection, nondestructive metallography, optics and lasers, fluid-structure interaction, vibrations, extensometry, modelling of structures refs., ills. [Espanol] Se presentan trabajos de CORENDE: Congreso Regional de Ensayos no Destructivos y Estructurales organizado por la Comision Nacional de Energia Atomica y la Universidad Tecnologica Nacional (Mendoza). Este congreso se propone como un foro de discusion, donde, desde la investigacion hasta la produccion y comercializacion, se intercambien y discutan ideas que sirvan de guia para fomentar ese necesario cambio cultural. Los topicos de discusion incluyen a todas las disciplinas presentes en la evaluacion de componentes, sistemas y estructuras: tecnicas no destructivas (ultrasonido, corrientes inducidas, radiografia industrial, emision acustica, particulas magnetizables, termografia, liquidos penetrantes, ensayos de perdidas, inspeccion visual, etc.), certificacion de personal, inspeccion en soldaduras, replicas metalograficas, tecnicas opticas y laser, interaccion fluido-estructura, vibraciones, extensometria, modelado de estructuras

  7. TABLE OF CINTENTS and ABSTRACTS reprinted from ACTA PHYSICA SINICA,Vol.50,No.6(2001)(in Chinese)


    @@0000 GENERAL 0330 Conservation Laws of Relativistic Variable Mass Systems…………………………… Fang Jian-hui (1005) 0340 Simulation of Shock Waves Using a Lattice Boltz mann Equation Model …………………… Feng Shi-de, Michihisa Tsutahara (1010) 0365 Double-Wave Function of RLC Circuit After Quantization…………………… Long Chao-yun, Liu Bo (1014) 0420 The Nernst Theorem and Statistical Entropy of the Scalar field in Reissner-Nordstrom Geometry……………………Zhao Ren, Zhang Li-chun (1018)

  8. Minutes of the third mining symposium, Mieres (1988). Actas de las 3. Jornadas de Mineria, Mieres (1988)

    Llaneza, L.J. (Comite Ejecutivo de la Feria de Mieres (Spain))


    The mining symposium was held in Mieres, Asturias, Spain sessions took place on: coal and its future - including technological research and development in Spain - the coordinating role of Ocicarbon, and principals pursued by HUNOSA in its opencast restoration work. Results obtained and coal and the EEC - including coal in the short and medium term, and Spanish mining within the European context.

  9. Comment on ;First experimental determination of the solubility constant of coffinite; [Geochim. Cosmochim. Acta 181 (2016) 36-53

    Konings, R. J. M.; Plyasunov, A.


    Coffinite - USiO4 - is a key mineral for the modelling of the chemistry of uranium in silica-rich rocks. It is of particular interest for the modelling of the final storage of used nuclear fuel in deep geological respositories, as coffinite may be the solubility-controlling solid phase for uranium. This was extensively discussed by Szenknect et al. (2016) in a recent publication of the determination of the solubility constant of coffinite. The availability of pure USiO4 samples made it possible for the first time to accurately determine the solubility of this phase in aqueous solution (under-saturated conditions with respect to silica in 0.1 mol L-1 HCl). The study by Szenknect et al. (2016) is very extensive and in combination with the calorimetric determination of the enthalpy of formation of USiO4 from the same material batch (Guo et al., 2015), allows a re-assessment of the thermodynamic properties of this phase, revising the values from the OECD/NEA review in 1992 (Grenthe et al., 1992) that were based on estimated values for the Gibbs energy of formation of USiO4 by Brookins (1975) and the standard entropy by Langmuir (1978).

  10. Erratum to "On guided wave propagation in fully clamped porous functionally graded nanoplates" [Acta Astronaut. 143 (2018) 380-390

    Karami, Behrouz; Janghorban, Maziar; Li, Li


    We found a proofing error existing in the affiliation of the first and second authors of our article [1], We found a proofing error existing in the affiliation of the first and second authors of our article [1]. The correct affiliation should be "Department of Mechanical Engineering, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran".

  11. Drug: D02780 [KEGG MEDICUS

    Full Text Available )2. Ca D02780.gif ... Neuropsychiatric agent ... DG01498 ... NMDA receptor antagonist Other ... DG01718 ... Drugs for add...ictive disorder ... DG01716 ... Drugs for alcohol dependence Therapeutic category: 1190 ATC code: N07BB03 Chemica

  12. Concentration dependence of in vivo biotransformation rates of organic sunscreen agents in rainbow trout following a dietary exposure

    Simple diffusion lipid-partitioning models have historically described the bioaccumulation of hydrophobic chemicals in fish. While these models are sufficient to describe the bioaccumulation of recalcitrant PCBs and other non-metabolized chemicals, they are inadequate for chemica...

  13. Reply to comment by Konings and Plyasunov on ;First experimental determination of the solubility constant of coffinite; [Geochim. Cosmochim. Acta 181 (2016) 36-53

    Szenknect, S.; Dacheux, N.; Ewing, R. C.; Navrotsky, A.


    R.J.M. Konings and A. Plyasunov investigated the values of thermodynamic data determined by Szenknect et al. (2016) from solubility experiments performed using a synthetic sample of coffinite. Especially, they focused on the value of the standard molar entropy, which was derived from these solubility data and the calorimetric measurement of the standard molar enthalpy of formation of coffinite published by Guo et al. (2015). The two independent measurements were performed on the same synthetic sample prepared by Mesbah et al. (2015) and fully characterized using complementary techniques by the two teams. We thank Konings and Plyasunov for their comment and the relevant analysis of previously published work. As they concluded, we agree that new experimental data are required to solve the ;coffinite issue;. Here, we simply wish to clarify a few points regarding the questions arising from their analysis.

  14. Actas del III Encuentro Platense de Investigadores/as sobre Cuerpo en las Artes Escénicas y Performáticas

    Sáez, Mariana Lucía


    Los días 4, 5 y 6 de septiembre de 2013, en el Centro Cultural Islas Malvinas de la ciudad de La Plata, se desarrolló el III ECART, Encuentro Platense de Investigadores sobre Cuerpo en las Artes Escénicas y Performáticas, organizado por el Grupo de Estudio sobre Cuerpo-Centro Interdisciplinario Cuerpo, Educación y Sociedad y la Compañía Proyecto en Bruto. En el transcurso de las tres jornadas de este nuevo encuentro se sucedieron talleres, conferencias, mesas de ponencias, obras de danza y...

  15. Personas y comunidades: Actas del Segundo Congreso Internacional de Buenas Prácticas en Patrimonio Mundial: (29 -30 de abril, 1 y 2 de mayo de 2015)

    Castillo Mena, Alicia R. (ed.)


    Este volumen está compuesto por una introducción y los textos de las comunicaciones y pósteres del congreso internacional, con una participación de 30 países y casi 100 centros de investigación. Recoge un documento de Buenas Prácticas sobre el tema.

  16. Simposio sobre Educacion de Ninas: Evidencias, Temas, Acciones. Actas de sesiones. (Symposium on Girls Education: Evidence, Issues, Actions. Proceedings). (Washington, DC, May 17-18, 2000).

    Agency for International Development (IDCA), Washington, DC.

    This symposium highlighted core issues of controversy in girls' education and developed implications for policy and practice. Its evidence-based discussion forum encouraged dialogue, debate, and increased interaction and developed partnerships among academic institutions, nongovernmental organizations, multilateral development agencies, and other…

  17. Proceedings of the 6. Argentine congress on radiation protection and nuclear safety; Actas del 6. congreso argentino de proteccion radiologica y seguridad nuclear



    The 6th Argentine Congress on Radiation Protection and Nuclear Safety was organized by the Radioprotection Argentine Society, in Buenos Aires, between the 22 and 24 of september of 1998. In this event, were presented almost 66 papers in the following sessions, about these subjects: 1.- Safety in nuclear installations. 2.- Control of nuclear material and physical protection of nuclear installations. 3.- Programs of quality assurance. 4.- Training, technical information and public information. 5.- Physical dosimetry. 6.- Physical dosimetry and occupational radiation protection. 7.- Exposure of the natural radiation. 8.- Environmental radiological safety. 9.- Biological effects of the ionizing radiations and biological dosimetry. 10.- Radiological protection of the medical practice and the radiological emergencies. 11.- Radioactive wastes management. 12.- Transport of radioactive materials

  18. Tetrodotoxin-induced conduction blockade is prolonged by hyaluronic acid with and without bupivacaine [Corrected from: Acta Anaesthesiol Scand 48 (1), 2004, 128-134

    Stevens, M. F.; Hoppe, M.; Holthusen, H.; Lipfert, P.


    BACKGROUND: In isolated nerves, tetrodotoxin (TTX) blocks nerve conduction longer than bupivacaine. In vivo, however, both substances block nerve conduction to an equal duration, presumably because the hydrophilic TTX binds only weakly to the perineural tissue. High molecular weight hyaluronic acid

  19. I Congreso Internacional sobre Domótica, Robótica y Teleasistencia para Todos. DRT4Aall 2005. Libro de Actas


    Este volumen recoge las comunicaciones y los pósteres (en forma resumida) presentados en la I Congreso Internacional sobre Domótica, Robótica y Teleasistencia para Todos, celebrado en Madrid en 2005. De los campos citados, el más representado aquí es la robótica, área en la que se dan conocer dispositivos de apoyo a la movilidad, a la rehabilitación médica y a la realización de actividades de la vida diaria, entre otras aplicaciones. Le siguen los contenidos sobre domótica, es decir, el diseñ...

  20. Tiny tweaks, big changes: An alternative strategy to empower ethical culture of human research in anesthesia (A Taiwan Acta Anesthesiologica Taiwanica-Ethics Review Task Force Report).

    Luk, Hsiang-Ning; Ennever, John F; Day, Yuan-Ji; Wong, Chih-Shung; Sun, Wei-Zen


    For this guidance article, the Ethics Review Task Force (ERTF) of the Journal reviewed and discussed the ethics issues related to publication of human research in the field of anesthesia. ERTF first introduced international ethics principles and minimal requirements of reporting of ethics practices, followed by discussing the universal problems of publication ethics. ERTF then compared the accountability and methodology of several medical journals in assuring authors' ethics compliance. Using the Taiwan Institutional Review Board system as an example, ERTF expressed the importance of institutional review board registration and accreditation to assure human participant protection. ERTF presented four major human research misconducts in the field of anesthesia in recent years. ERTF finally proposed a flow-chart to guide journal peer reviewers and editors in ethics review during the editorial process in publishing. Examples of template languages applied in the Ethics statement section in the manuscript are expected to strengthen the ethics compliance of the authors and to set an ethical culture for all the stakeholders involved in human research. Copyright © 2015. Published by Elsevier B.V.

  1. An analysis of U.S. Army Corps of Engineers documents supporting the channelization of the Rio Piedras. Acta Cientifica. 27(1-3).

    Ariel Lugo; C.J. Nytch; M. Ramsey


    This paper has three objectives: 1) to provide a synopsis of the content of the reports, documents, data, and arguments used by the Corps to justify the channelization of the Rio Piedras; 2) to evaluate the accuracy of predictions and assumptions used by the Corps to reach conclusions that justify the channelization of the Rio Piedras; and 3) to make a case for the...

  2. Actas de la Segunda conferencia internacional en ciencia de la computacion (proceedings of the 2nd international conference on computer science)


    The following topics were dealt with: relational databases; memory unit environments; artificial intelligence systems; programming theory; functional programming; distributed systems; and abstract data types. 13 papers were presented, of which 13 are published in full in the present proceedings. Abstracts of individual papers can be found under the relevant classification codes in this or other issues.

  3. Addressing the Issue of Microplastics in the Wake of the Microbead-Free Waters Act-A New Standard Can Facilitate Improved Policy.

    McDevitt, Jason P; Criddle, Craig S; Morse, Molly; Hale, Robert C; Bott, Charles B; Rochman, Chelsea M


    The United States Microbead-Free Waters Act was signed into law in December 2015. It is a bipartisan agreement that will eliminate one preventable source of microplastic pollution in the United States. Still, the bill is criticized for being too limited in scope, and also for discouraging the development of biodegradable alternatives that ultimately are needed to solve the bigger issue of plastics in the environment. Due to a lack of an acknowledged, appropriate standard for environmentally safe microplastics, the bill banned all plastic microbeads in selected cosmetic products. Here, we review the history of the legislation and how it relates to the issue of microplastic pollution in general, and we suggest a framework for a standard (which we call "Ecocyclable") that includes relative requirements related to toxicity, bioaccumulation, and degradation/assimilation into the natural carbon cycle. We suggest that such a standard will facilitate future regulation and legislation to reduce pollution while also encouraging innovation of sustainable technologies.

  4. Erratum to : Modeling of complex interfaces for pendant drop experiments (Rheologica Acta, , 55, 10, (801-822), 10.1007/s00397-016-0956-1)

    Balemans, C.; Hulsen, M.A.; Tervoort, T.A.; Anderson, P.D.


    The original version of this article unfortunately contained mistakes. Theo A. Tervoort was not listed among the authors. The correct information is given above. In Balemans et al. (2016), an axisymmetric finite element model is presented to study the behaviour of complex interfaces in pendant drop

  5. VI Actas Congreso. Miedos, culpas, violencias invisibles y su impacto en la vida de las mujeres: ¡A vueltas con el amor!

    Gil Gómez, Alicia; Escrig Gil, Gemma; Forcada Martínez, Águeda


    ÍNDICE. Presentación,ESPERANZA BOSCH FIOL. Introducción poética, PACA GABALDÓN, CLAUDIA GRAVI Y Mª LUISA SAN JOSÉ. Justo el amor, MARÍA XOSÉ AGRA ROMERO. I. CONFERENCIAS El género en cuestión. Modelos imposibles y modelos perversos,DOLORES JULIANO CORREGIDO. La propia identidad y las relaciones de amor en la adolescencia, AURORA LEAL GARCÍA Feelings of fear and guilt among women in conflicts and wars.Miedos y culpas de mujeres en situaciones de conflictos y de guerra, RAN...

  6. Terpene chemodiversity of relict conifers Picea omorika, Pinus heldreichii, and Pinus peuce, endemic to Balkan.

    Nikolić, Biljana; Ristić, Mihailo; Tešević, Vele; Marin, Petar D; Bojović, Srdjan


    Terpenes are often used as ecological and chemotaxonomic markers of plant species, as well as for estimation of geographic variability. Essential oils of relic and Balkan endemic/subendemic conifers, Picea omorika, Pinus heldreichii, and P. peuce, in central part of Balkan Peninsula (Serbia and Montenegro), on the level of terpene classes and common terpene compounds were investigated. In finding terpene combinations, which could show the best diversity between species and their natural populations, several statistical methods were applied. Apart from the content of different terpene classes (P. omorika has the most abundant O-containing monoterpenes and sesquiterpenes; P. heldreichii and P. peuce have the largest abundance of sesquiterpene and monoterpene hydrocarbons, resp.), the species are clearly separated according to terpene profile with 22 common compounds. But, divergences in their populations were established only in combination of several compounds (specific for each species), and they were found to be the results of geomorphologic, climatic, and genetic factors. We found similarities between investigated species and some taxa from literature with respect to terpene composition, possibly due to hybridization and phylogenetic relations. Obtained results are also important regarding to chemotaxonomy, biogeography, phylogeny, and evolution of these taxa. Copyright © 2011 Verlag Helvetica Chimica Acta AG, Zürich.

  7. Phytochemistry of the carnivorous sundew genus Drosera (Droseraceae) - future perspectives and ethnopharmacological relevance.

    Egan, Paul A; van der Kooy, Frank


    Species of the carnivorous genus Drosera L. have long been a source of valuable natural products. The various phytochemicals characteristic of these species, particularly 1,4-naphthoquinones and flavonoids, have contributed to the diverse utilization of sundews in traditional medicine systems worldwide. A growing number of studies have sought to investigate the comparative phytochemistry of Drosera species for improved sources of pharmaceutically important compounds. The outcomes of these studies are here collated, with emergent trends discussed in detail. Important factors which affect production of secondary metabolites in plants are critically examined, such as environmental influences and in vitro culture, and recommendations subsequently presented based on this. Explicitly, the current review aims to i) present an updated, comprehensive listing of the phytochemical constituents of the genus (including quantitative data where available), ii) summarize important factors which may influence the production of phytopharmaceuticals in plants, and iii) recommend guidelines for future research based on the above, including improved standardization and quality control. We have also included a section discussing future perspectives of research on Drosera spp. based on three different research lines i) the potential to produce much needed lead compounds for treatment of tuberculosis, ii) the potential role of anthocyanins in nitrogen transport, and iii) research into 'Natural Deep Eutectic' solvents produced by Drosera spp. in the droplets or 'dew' employed to capture insect prey. Copyright © 2013 Verlag Helvetica Chimica Acta AG, Zürich.

  8. Identification and quantitation of new glutamic acid derivatives in soy sauce by UPLC/MS/MS.

    Frerot, Eric; Chen, Ting


    Glutamic acid is an abundant amino acid that lends a characteristic umami taste to foods. In fermented foods, glutamic acid can be found as a free amino acid formed by proteolysis or as a non-proteolytic derivative formed by microorganisms. The aim of the present study was to identify different structures of glutamic acid derivatives in a typical fermented protein-based food product, soy sauce. An acidic fraction was prepared with anion-exchange solid-phase extraction (SPE) and analyzed by UPLC/MS/MS and UPLC/TOF-MS. α-Glutamyl, γ-glutamyl, and pyroglutamyl dipeptides, as well as lactoyl amino acids, were identified in the acidic fraction of soy sauce. They were chemically synthesized for confirmation of their occurrence and quantified in the selected reaction monitoring (SRM) mode. Pyroglutamyl dipeptides accounted for 770 mg/kg of soy sauce, followed by lactoyl amino acids (135 mg/kg) and γ-glutamyl dipeptides (70 mg/kg). In addition, N-succinoylglutamic acid was identified for the first time in food as a minor compound in soy sauce (5 mg/kg). Copyright © 2013 Verlag Helvetica Chimica Acta AG, Zürich.

  9. Biomolecular characterization of wild sicilian oregano: phytochemical screening of essential oils and extracts, and evaluation of their antioxidant activities.

    Tuttolomondo, Teresa; La Bella, Salvatore; Licata, Mario; Virga, Giuseppe; Leto, Claudio; Saija, Antonella; Trombetta, Domenico; Tomaino, Antonio; Speciale, Antonio; Napoli, Edoardo M; Siracusa, Laura; Pasquale, Andrea; Curcuruto, Giusy; Ruberto, Giuseppe


    An extensive survey of wild Sicilian oregano was made. A total of 57 samples were collected from various sites, followed by taxonomic characterization from an agronomic perspective. Based on morphological and production characteristics obtained from the 57 samples, cluster analysis was used to divide the samples into homogeneous groups, to identify the best biotypes. All samples were analyzed for their phytochemical content, applying a cascade-extraction protocol and hydrodistillation, to obtain the non volatile components and the essential oils, respectively. The extracts contained thirteen polyphenol derivatives, i.e., four flavanones, seven flavones, and two organic acids. Their qualitative and quantitative characterization was carried out by LC/MS analyses. The essential oils were characterized using a combination of GC-FID and GC/MS analyses; a total of 81 components were identified. The major components of the oils were thymol, p-cymene, and γ-terpinene. Cluster analysis was carried out on both phytochemical profiles and resulted in the division of the oregano samples into different chemical groups. The antioxidant activity of the essential oils and extracts was investigated by the Folin-Ciocalteau (FC) colorimetric assay, by UV radiation-induced peroxidation in liposomal membranes (UV-IP test), and by determining the O(2)(∙-)-scavenging activity. Copyright © 2013 Verlag Helvetica Chimica Acta AG, Zürich.

  10. Free-Radical-Scavenging, Antityrosinase, and Cellular Melanogenesis Inhibitory Activities of Synthetic Isoflavones.

    Lu, Tzy-Ming; Ko, Horng-Huey; Ng, Lean-Teik; Hsieh, Yen-Pin


    In this study, we examined the potential of synthetic isoflavones for application in cosmeceuticals. Twenty-five isoflavones were synthesized and their capacities of free-radical-scavenging and mushroom tyrosinase inhibition, as well as their impact on cell viability of B16F10 murine melanoma cells and HaCaT human keratinocytes were evaluated. Isoflavones that showed significant mushroom tyrosinase inhibitory activities were further studied on reduction of cellular melanin formation and antityrosinase activities in B16F10 melanocytes in vitro. Among the isoflavones tested, 6-hydroxydaidzein (2) was the strongest scavenger of both ABTS(.+) and DPPH(.) radicals with SC50 values of 11.3 ± 0.3 and 9.4 ± 0.1 μM, respectively. Texasin (20) exhibited the most potent inhibition of mushroom tyrosinase (IC50 14.9 ± 4.5 μM), whereas retusin (17) showed the most efficient inhibition both of cellular melanin formation and antityrosinase activity in B16F10 melanocytes, respectively. In summary, both retusin (17) and texasin (20) exhibited potent free-radical-scavenging capacities as well as efficient inhibition of cellular melanogenesis, suggesting that they are valuable hit compounds with potential for advanced cosmeceutical development. Copyright © 2015 Verlag Helvetica Chimica Acta AG, Zürich.

  11. Essential-Oil Variability in Natural Populations of Pinus mugo Turra from the Julian Alps.

    Bojović, Srdjan; Jurc, Maja; Ristić, Mihailo; Popović, Zorica; Matić, Rada; Vidaković, Vera; Stefanović, Milena; Jurc, Dušan


    The composition and variability of the terpenes and their derivatives isolated from the needles of a representative pool of 114 adult trees originating from four natural populations of dwarf mountain pine (Pinus mugo Turra) from the Julian Alps were investigated by GC-FID and GC/MS analyses. In total, 54 of the 57 detected essential-oil components were identified. Among the different compound classes present in the essential oils, the chief constituents belonged to the monoterpenes, comprising an average content of 79.67% of the total oil composition (74.80% of monoterpene hydrocarbons and 4.87% of oxygenated monoterpenes). Sesquiterpenes were present in smaller amounts (average content of 19.02%), out of which 16.39% were sesquiterpene hydrocarbons and 2.62% oxygenated sesquiterpenes. The most abundant components in the needle essential oils were the monoterpenes δ-car-3-ene, β-phellandrene, α-pinene, β-myrcene, and β-pinene and the sesquiterpene β-caryophyllene. From the total data set of 57 detected compounds, 40 were selected for principal-component analysis (PCA), discriminant analysis (DA), and cluster analysis (CA). The overlap tendency of the four populations suggested by PCA, was as well observed by DA. CA also demonstrated similarity among the populations, which was the highest between Populations I and II. Copyright © 2016 Verlag Helvetica Chimica Acta AG, Zürich.

  12. Chemotaxonomic significance of the terpene composition in natural populations of Pinus nigra J.F.Arnold from Serbia.

    Sarac, Zorica; Bojović, Srdjan; Nikolić, Biljana; Tešević, Vele; Ethorđević, Iris; Marin, Petar D


    The essential-oil variability in seven native populations belonging to different infraspecific taxa of Pinus nigra (ssp. nigra, var. gocensis, ssp. pallasiana, and var. banatica) growing wild in Serbia was analyzed. In the needles of 195 trees from seven populations, 58 essential-oil components were identified. The major components were α-pinene (43.6%) and germacrene D (29.8%), comprising together 73.4% of the total oil composition. Based on the average chemical profile of the main terpene components (with contents >5%), the studied populations were found to be the most similar to populations from central Italy and Greece (ssp. nigra). Cluster analysis showed the division of the populations into three principal groups: the first group consisted of Populations I, II, III, IV, and V (considered as ssp. nigra group), the second of Population VI (ssp. pallasiana group), and the third of Population VII, which had the most distinct oil composition (ssp. banatica group). The taxonomic implications of the essential-oil profiles of the investigated taxa of this very complex species are discussed. Copyright © 2013 Verlag Helvetica Chimica Acta AG, Zürich.

  13. Composition and Chemical Variability of the Needle Oil from Pinus halepensis growing in Corsica.

    Nam, Anne-Marie; Tomi, Félix; Gibernau, Marc; Casanova, Joseph; Bighelli, Ange


    The composition of oil samples isolated from needles of Pinus halepensis growing in three locations in Corsica (Saleccia, Capo di Feno, and Tre Padule) has been investigated by combination of chromatographic (GC with retention indices) and spectroscopic (MS and (13)C-NMR) techniques. In total, 35 compounds that accounted for 77 - 100% of the whole composition have been identified. α-Pinene, myrcene, and (E)-β-caryophyllene were the major component followed by α-humulene and 2-phenylethyl isovalerate. Various diterpenes have been identified as minor components. 47 Oil samples isolated from pine needles have been analyzed and were differentiated in two groups. Oil samples of the first group (15 samples) contained myrcene (M = 28.1 g/100 g; SD = 10.6) and (E)-β-caryophyllene (M = 19.0 g/100 g; SD = 2.2) as major components and diterpenes were absent. All these oil samples were isolated from pine needles harvested in Saleccia. Oil samples of the second group (32 samples) contained mostly (E)-β-caryophyllene (M = 28.7 g/100 g; SD = 7.9), α-pinene (M = 12.3 g/100 g; SD = 3.6), and myrcene (M = 11.7 g/100 g; SD = 7.3). All these oil samples were isolated from pine needles harvested in Capo di Feno and Tre Padule. © 2016 Verlag Helvetica Chimica Acta AG, Zürich.

  14. Sea sand disruption method (SSDM) as a valuable tool for isolating essential oil components from conifers.

    Dawidowicz, Andrzej L; Czapczyńska, Natalia B


    Essential oils are one of nature's most precious gifts with surprisingly potent and outstanding properties. Coniferous oils, for instance, are nowadays being used extensively to treat or prevent many types of infections, modify immune responses, soothe inflammations, stabilize moods, and to help ease all forms of non-acute pain. Given the broad spectrum of usage of coniferous essential oils, a fast, safe, simple, and efficient sample-preparation method is needed in the estimation procedure of essential oil components in fresh plant material. Generally, the time- and energy-consuming steam distillation (SD) is applied for this purpose. This paper will compare SD, pressurized liquid extraction (PLE), matrix solid-phase dispersion (MSPD), and the sea sand disruption method (SSDM) as isolation techniques to obtain aroma components from Scots pine (Pinus sylvestris), spruce (Picea abies), and Douglas fir (Pseudotsuga menziesii). According to the obtained data, SSDM is the most efficient sample preparation method in determining the essential oil composition of conifers. Moreover, SSDM requires small organic solvent amounts and a short extraction time, which makes it an advantageous alternative procedure for the routine analysis of coniferous oils. The superiority of SSDM over MSPD efficiency is ascertained, as there are no chemical interactions between the plant cell components and the sand. This fact confirms the reliability and efficacy of SSDM for the analysis of volatile oil components. Copyright © 2011 Verlag Helvetica Chimica Acta AG, Zürich.

  15. Relevance of the Sea Sand Disruption Method (SSDM) for the biometrical differentiation of the essential-oil composition from conifers.

    Dawidowicz, Andrzej L; Czapczyńska, Natalia B; Wianowska, Dorota


    Sea Sand Disruption Method (SSDM) is a simple and cheap sample-preparation procedure allowing the reduction of organic solvent consumption, exclusion of sample component degradation, improvement of extraction efficiency and selectivity, and elimination of additional sample clean-up and pre-concentration step before chromatographic analysis. This article deals with the possibility of SSDM application for the differentiation of essential-oils components occurring in the Scots pine (Pinus sylvestris L.) and cypress (Cupressus sempervirens L.) needles from Madrid (Spain), Laganas (Zakhyntos, Greece), Cala Morell (Menorca, Spain), Lublin (Poland), Helsinki (Finland), and Oradea (Romania). The SSDM results are related to the analogous - obtained applying two other sample preparation methods - steam distillation and Pressurized Liquid Extraction (PLE). The results presented established that the total amount and the composition of essential-oil components revealed by SSDM are equivalent or higher than those obtained by one of the most effective extraction technique, PLE. Moreover, SSDM seems to provide the most representative profile of all essential-oil components as no heat is applied. Thus, this environmentally friendly method is suggested to be used as the main extraction procedure for the differentiation of essential-oil components in conifers for scientific and industrial purposes. Copyright © 2013 Verlag Helvetica Chimica Acta AG, Zürich.

  16. Variability in chemical composition and abundance of the rare tertiary relict Pinus heldreichii in Serbia.

    Bojović, Srdjan; Nikolić, Biljana; Ristić, Mihailo; Orlović, Saša; Veselinović, Milorad; Rakonjac, Ljubinko; Dražić, Dragana


    The particular significance of the whitebark pine (Pinus heldreichii Christ.) stems from the fact that it is a tertiary relict and Balkanic subendemite covering a very narrow and intermittent area in Serbia. A representative pool of 48 adult trees originating from three populations, one recently discovered natural (Population I) and two planted populations (Populations II and III) was investigated in order to evaluate the intra- and interpopulation variability of the essential oil of the complete fund of P. heldreichii in Serbia. In the pine-needle-terpene profile, 104 compounds were detected, 84 of which could be identified. Among the essential-oil constituents, monoterpenes and sesquiterpenes dominated, comprising ca. 90% of the essential oil. The terpenic profile of Population I was characterized by a predominance of monoterpenes (e.g., limonene (1), α-pinene, and Δ(3) -carene (4)), while sesquiterpenes (e.g., germacrene D (2) and β-caryophyllene (3)) obviously preponderated in the profile of Populations II and III. This study also demonstrated that the abundance of whitebark pines in Serbia had significantly changed over the last few decades. The number of individuals in the natural population had increased, while the number of individuals in the planted populations had decreased. Today, the whitebark pine fund in Serbia comprises less than 250 trees. 2011 Verlag Helvetica Chimica Acta AG, Zürich.

  17. Influence of mannosylation on immunostimulating activity of adamant-1-yl tripeptide.

    Ribić, Rosana; Habjanec, Lidija; Frkanec, Ruža; Vranešić, Branka; Tomić, Srđanka


    The mannosylated derivative of adamant-1-yl tripeptide (D-(Ad-1-yl)Gly-L-Ala-D-isoGln) was prepared to study the effects of mannosylation on adjuvant (immunostimulating) activity. Mannosylated adamant-1-yl tripeptide (Man-OCH(2) CH(Me)CO-D-(Ad-1-yl)Gly-L-Ala-D-isoGln) is a non-pyrogenic, H(2) O-soluble, and non-toxic compound. Adjuvant activity of mannosylated adamantyl tripeptide was tested in the mouse model with ovalbumin as an antigen and in comparison to the parent tripeptide and peptidoglycan monomer (PGM, β-D-GlcNAc-(1→4)-D-MurNAc-L-Ala-D-isoGln-mesoDAP(εNH(2) )-D-Ala-D-Ala), a well-known effective adjuvant. The mannosylation of adamantyl tripeptide caused the amplification of its immunostimulating activity in such a way that it was comparable to that of PGM. Copyright © 2012 Verlag Helvetica Chimica Acta AG, Zürich.

  18. Antioxidant Properties and Flavonoid Profile in Leaves of Calabrian Lavandula multifida L., an Autochthon Plant of Mediterranean Southern Regions.

    Panuccio, Maria Rosaria; Fazio, Angela; Papalia, Teresa; Barreca, Davide


    Lavandula multifida is a rare short-lived plant characteristic of Mediterranean basin able to survive in hot and arid climatic conditions on poorly evolved limestone soils. In this work, we characterize the enzymatic antioxidant system and phenolic composition, as well as the antioxidant properties of L. multifida fresh leaves. Enzymatic patterns show high level of peroxidases, ascorbate peroxidase, and dehydroascorbate reductase activities, when compared with L. angustifolia. The same trend is evident in total carotenoids, ascorbic acid, and reduced glutathione, and in the total antioxidant capacity assay. Moreover, RP-DAD-HPLC analyses of EtOH extract, obtained from fresh leaves, reveal main components, carvacrol, vitexin, and 7- or 8-glucoside derivatives of hypolaetin, scutellarein, luteolin, isoscutellarein, apigenin, and chrysoeriol. The analysis of this autochthon plant depicted a series of strategies adopted by L. multifida to survive in its stressful natural habitat and richness in health-promoting compounds that can be a resource for the preservation of this variety in dangerous of extinction. © 2016 Verlag Helvetica Chimica Acta AG, Zürich.

  19. Essential oils from wild populations of Algerian Lavandula stoechas L.: composition, chemical variability, and in vitro biological properties.

    Benabdelkader, Tarek; Zitouni, Abdelghani; Guitton, Yann; Jullien, Frédéric; Maitre, Dany; Casabianca, Hervé; Legendre, Laurent; Kameli, Abdelkrim


    In an effort to develop local productions of aromatic and medicinal plants, a comprehensive assessment of the composition and biological activities of the essential oils (EOs) extracted from the aerial flowering parts of wild growing Lavandula stoechas L. collected from eleven different locations in northern Algeria was performed. The oils were characterized by GC-FID and GC/MS analyses, and 121 compounds were identified, accounting for 69.88-91.2% of the total oil compositions. The eleven oils greatly differed in their compositions, since only 66 compounds were common to all oils. Major EO components were fenchone (2; 11.27-37.48%), camphor (3, 1.94-21.8%), 1,8-cineole (1; 0.16-8.71%), and viridiflorol (10; 2.89-7.38%). The assessed in vitro biological properties demonstrated that the DPPH-based radical-scavenging activities and the inhibition of the β-carotene/linoleic acid-based lipid oxidation differed by an eight-fold factor between the most and the least active oils and were linked to different sets of molecules in the different EOs. The eleven EOs exhibited good antimicrobial activities against most of the 16 tested strains of bacteria, filamentous fungi, and yeasts, with minimum inhibitory concentrations (MICs) ranging from 0.16 to 11.90 mg/ml. Copyright © 2011 Verlag Helvetica Chimica Acta AG, Zürich.

  20. Comparison of the Composition and Antimicrobial Activities of the Essential Oils of Green Branches and Leaves of Egyptian Navel Orange (Citrus sinensis (L.) Osbeck var. malesy).

    Eldahshan, Omayma A; Halim, Ahmed F


    The essential oils isolated from the leaves and green branches of the Egyptian navel orange trees were analyzed by GC and GC/MS. A total of 33 and 24 compounds were identified from the oils of the leaves and branches accounting for 96.0% and 97.9%, respectively, of the total detected constituents. The major ones were sabinene (36.5; 33.0%), terpinen-4-ol (8.2; 6.2%), δ-3-carene (7.0; 9.4%), limonene (6.8; 18.7%), trans-ocimene (6.7; 6.1%), and β-myrcene (4.5; 4.4%). The antimicrobial activities of both oils were evaluated using the agar-well diffusion method toward three representatives for each of Gram-positive bacteria, Gram-negative bacteria, and fungi. The oil of leaves was more effective as antimicrobial agent than that of the branches. Streptococcus pyogenes, Staphylococcus aureus, Salmonella typhimurium, and Aspergillus fumigatus were the most sensitive bacteria and fungi by the leaves oil. © 2016 Verlag Helvetica Chimica Acta AG, Zürich.

  1. 'Does my Diet Affect my Perfume?' Identification and Quantification of Cuticular Compounds in Five Drosophila melanogaster Strains Maintained over 300 Generations on Different Diets.

    Pavković-Lučić, Sofija; Todosijević, Marina; Savić, Tatjana; Vajs, Vlatka; Trajković, Jelena; Anđelković, Boban; Lučić, Luka; Krstić, Gordana; Makarov, Slobodan; Tomić, Vladimir; Miličić, Dragana; Vujisić, Ljubodrag


    Cuticular hydrocarbons (CHCs) in Drosophila melanogaster represent the basis of chemical communication being involved in many important biological functions. The aim of this study was to characterize chemical composition and variation of cuticular profiles in five D. melanogaster strains. These strains were reared for approximately 300 generations on five diets: standard cornmeal medium and substrates prepared with apple, banana, tomato, and carrot. Differences in quantity and/or quality in CHCs were assumed as a result of activation of different metabolic pathways involved in food digestion and adaptations to the particular diet type. In total, independently of sex and strain, 66 chemical compounds were identified. In females of all strains, 60 compounds were identified, while, in males, 47 compounds were extracted. Certain new chemical compounds for D. melanogaster were found. MANOVA confirmed that CHC amounts significantly depend on sex and substrates, as well as on their interactions. Discriminant analysis revealed that flies belonging to 'apple' and 'carrot' strains exhibited the most noticeable differences in CHC repertoires. A non-hydrocarbon pheromone, cis-vaccenyl acetate (cVA) also contributed to the variation in the pheromone bouquet among the strains. Variability detected in CHCs and cVA may be used in the explanation of differences in mating behaviour previously determined in analyzed fly strains. Copyright © 2016 Verlag Helvetica Chimica Acta AG, Zürich.

  2. Chemical Composition of Juniperus communis L. Cone Essential Oil and Its Variability among Wild Populations in Kosovo.

    Hajdari, Avni; Mustafa, Behxhet; Nebija, Dashnor; Miftari, Elheme; Quave, Cassandra L; Novak, Johannes


    Ripe cones of Juniperus communis L. (Cupressaceae) were collected from five wild populations in Kosovo, with the aim of investigating the chemical composition and natural variation of essential oils between and within wild populations. Ripe cones were collected, air dried, crushed, and the essential oils obtained by hydrodistillation. The essential-oil constituents were identified by GC-FID and GC/MS analyses. The yield of essential oil differed depending on the population origins and ranged from 0.4 to 3.8% (v/w, based on the dry weight). In total, 42 compounds were identified in the essential oils of all populations. The principal components of the cone-essential oils were α-pinene, followed by β-myrcene, sabinene, and D-limonene. Taking into consideration the yield and chemical composition, the essential oil originating from various collection sites in Kosovo fulfilled the minimum requirements for J. communis essential oils of the European Pharmacopoeia. Hierarchical cluster analysis (HCA) and principal component analysis (PCA) were used to determine the influence of the geographical variations on the essential-oil composition. These statistical analyses suggested that the clustering of populations was not related to their geographic location, but rather appeared to be linked to local selective forces acting on the chemotype diversity. Copyright © 2015 Verlag Helvetica Chimica Acta AG, Zürich.

  3. Dittrichia graveolens (L.) Greuter Essential Oil: Chemical Composition, Multivariate Analysis, and Antimicrobial Activity.

    Mitic, Violeta; Stankov Jovanovic, Vesna; Ilic, Marija; Jovanovic, Olga; Djordjevic, Aleksandra; Stojanovic, Gordana


    The chemical composition and in vitro antimicrobial activities of Dittrichia graveolens (L.) Greuter essential oil was studied. Moreover, using agglomerative hierarchical cluster (AHC) and principal component analyses (PCA), the interrelationships of the D. graveolens essential-oil profiles characterized so far (including the sample from this study) were investigated. To evaluate the chemical composition of the essential oil, GC-FID and GC/MS analyses were performed. Altogether, 54 compounds were identified, accounting for 92.9% of the total oil composition. The D. graveolens oil belongs to the monoterpenoid chemotype, with monoterpenoids comprising 87.4% of the totally identified compounds. The major components were borneol (43.6%) and bornyl acetate (38.3%). Multivariate analysis showed that the compounds borneol and bornyl acetate exerted the greatest influence on the spatial differences in the composition of the reported oils. The antimicrobial activity against five bacterial and one fungal strain was determined using a disk-diffusion assay. The studied essential oil was active only against Gram-positive bacteria. Copyright © 2016 Verlag Helvetica Chimica Acta AG, Zürich.

  4. Bioprospecting Chemical Diversity and Bioactivity in a Marine Derived Aspergillus terreus.

    Adpressa, Donovon A; Loesgen, Sandra


    A comparative metabolomic study of a marine derived fungus (Aspergillus terreus) grown under various culture conditions is presented. The fungus was grown in eleven different culture conditions using solid agar, broth cultures, or grain based media (OSMAC). Multivariate analysis of LC/MS data from the organic extracts revealed drastic differences in the metabolic profiles and guided our subsequent isolation efforts. The compound 7-desmethylcitreoviridin was isolated and identified, and is fully described for the first time. In addition, 16 known fungal metabolites were also isolated and identified. All compounds were elucidated by detailed spectroscopic analysis and tested for antibacterial activities against five human pathogens and tested for cytotoxicity. This study demonstrates that LC/MS based multivariate analysis provides a simple yet powerful tool to analyze the metabolome of a single fungal strain grown under various conditions. This approach allows environmentally-induced changes in metabolite expression to be rapidly visualized, and uses these differences to guide the discovery of new bioactive molecules. Copyright © 2016 Verlag Helvetica Chimica Acta AG, Zürich.

  5. Small organic solutes in sticky droplets from orb webs of the spider Zygiella atrica (Araneae; Araneidae): β-alaninamide is a novel and abundant component.

    Townley, Mark A; Pu, Qinglin; Zercher, Charles K; Neefus, Christopher D; Tillinghast, Edward K


    In northeastern North America, Zygiella atrica often build their orb webs near the ocean. We analyzed individual field-built Z. atrica webs to determine if organic low-molecular-mass solutes (LMM) in their sticky droplets showed any unusual features not previously seen in orb webs of other species living in less salty environments. While two of the three most abundant organic LMM (putrescine (butane-1,4-diamine) and GABamide (4-aminobutanamide)) are already well-known from webs of inland spiders, the third major LMM, β-alaninamide (3-aminopropanamide), a homolog of GABamide, has not been detected in sticky droplets from any other araneoid spiders (27 species). It remains to be established, however, whether or not use of β-alaninamide is related to proximity to saltwater. We observed variability in organic LMM composition in Z. atrica webs that appeared to be influenced more by an undetermined factor associated with different collecting locations and/or collection dates than by different genders or instars. Shifts in composition when adult females were transferred from the field to the laboratory were also observed. Structural similarities and inverse correlations among β-alaninamide, GABamide, and N-acetylputrescine suggest that they may form a series of LMM fulfilling essentially the same, as yet unknown, role in the webs of those species in which they occur. Copyright © 2012 Verlag Helvetica Chimica Acta AG, Zürich.

  6. Argania spinosa var. mutica and var. apiculata: variation of fatty-acid composition, phenolic content, and antioxidant and α-amylase-inhibitory activities among varieties, organs, and development stages.

    El Adib, Saifeddine; Aissi, Oumayma; Charrouf, Zoubida; Ben Jeddi, Fayçal; Messaoud, Chokri


    Argania spinosa includes two varieties, var. apiculata and var. mutica. These argan varieties were introduced into Tunisia in ancient times and are actually cultivated in some botanic gardens. Little is known about the chemical differentiation among these argan varieties. Hence, the aim of this study was to determine the fatty-acid composition, the total phenolic and flavonoid contents, and the antioxidant and α-amylase-inhibitory activities of leaf, seed, and pulp extracts of both argan varieties harvested during the months of January to April. The fatty-acid distribution was found to depend on the argan variety, the plant organ, and the harvest time. Significant variations in the phenolic contents were observed between the investigated varieties as well as between leaves, pulps, and seeds of each variety. As expected, phenolic compounds were found to be contributors to the antioxidant and α-amylase-inhibitory activities of both argan varieties. The chemical differentiation observed among the two argan varieties, based mainly on the fatty-acid composition, might have some chemotaxonomic value. Copyright © 2015 Verlag Helvetica Chimica Acta AG, Zürich.

  7. Sebaceous lipid profiling of bat integumentary tissues: quantitative analysis of free Fatty acids, monoacylglycerides, squalene, and sterols.

    Pannkuk, Evan L; Gilmore, David F; Fuller, Nathan W; Savary, Brett J; Risch, Thomas S


    White-nose syndrome (WNS) is a fungal disease caused by Pseudogymnoascus destructans and is devastating North American bat populations. Sebaceous lipids secreted from host integumentary tissues are implicated in the initial attachment and recognition of host tissues by pathogenic fungi. We are interested in determining if ratios of lipid classes in sebum can be used as biomarkers to diagnose severity of fungal infection in bats. To first establish lipid compositions in bats, we isolated secreted and integral lipid fractions from the hair and wing tissues of three species: big brown bats (Eptesicus fuscus), Eastern red bats (Lasiurus borealis), and evening bats (Nycticeius humeralis). Sterols, FFAs, MAGs, and squalene were derivatized as trimethylsilyl esters, separated by gas chromatography, and identified by mass spectrometry. Ratios of sterol to squalene in different tissues were determined, and cholesterol as a disease biomarker was assessed. Free sterol was the dominant lipid class of bat integument. Squalene/sterol ratio is highest in wing sebum. Secreted wing lipid contained higher proportions of saturated FFAs and MAGs than integral wing or secreted hair lipid. These compounds are targets for investigating responses of P. destructans to specific host lipid compounds and as biomarkers to diagnose WNS. Copyright © 2013 Verlag Helvetica Chimica Acta AG, Zürich.

  8. Synthesis, characterization, and DNA binding and cleavage properties of copper(II)-tryptophanphenyl-alanine-1,10-phenanthroline/2,2'-bipyridine complexes.

    Reddy, Pulimamidi R; Raju, Nomula; Satyanarayana, Battu


    The mononuclear dipeptide-based Cu(II) complexes [Cu(II) (trp-phe)(phen)(H₂O)] ⋅ ClO₄ (1) and [Cu(II) (trp-phe)(bpy)(H₂O)] ⋅ ClO₄ (2) (trp-phe=tryptophanphenylalanine, phen=1,10-phenanthroline, bpy=2,2'-bipyridine) were isolated, and their interaction with DNA was studied. They exhibit intercalative mode of interaction with DNA. The intercalative interaction was quantified by Stern-Volmer quenching constant (K(sq) =0.14 for 1 and 0.08 for 2). The Cu(II) complexes convert supercoiled plasmid DNA into its nicked circular form hydrolytically at physiological conditions at a concentration as low as 5 μM (for 1) and 10 μM (for 2). The DNA hydrolysis rates at a complex concentration of 50 μM were determined as 1.74 h(-1) (R=0.985) for 1 and 0.65 h(-1) (R=0.965) for 2. The rate enhancement in the range of 2.40-4.10×10⁷-fold compared to non-catalyzed double-stranded DNA is significant. This was attributed to the presence of a H(2) O molecule in the axial position of the Cu complexes. Copyright © 2011 Verlag Helvetica Chimica Acta AG, Zürich.

  9. Development of new natural extracts.

    Lavoine-Hanneguelle, Sophie; Périchet, Christine; Schnaebele, Nicolas; Humbert, Marina


    For over the past 20 years, a remarkable development in the study and search of natural products has been observed. This is linked to a new market trend towards ecology and also due to new regulations. This could be a rupture, but also a real booster for creativity. Usually, in the flavor and fragrance field, creativity was boosted by the arrival of new synthetic molecules. Naturals remained the traditional, century-old products, protected by secrecy and specific know-how from each company. Regulatory restrictions or eco-friendly certification constraints like hexane-free processes triggered an important brainstorming in the industry. As a result, we developed new eco-friendly processes including supercritical CO2 extraction, allowing fresh plants to be used to obtain industrial flower extracts (Jasmine Grandiflorum, Jasmine Sambac, Orange blossom). These extracts are analyzed by GC, GC/MS, GCO, and HPTLC techniques. New or unusual raw materials can also be explored, but the resulting extracts have to be tested for safety reasons. Some examples are described. Copyright © 2014 Verlag Helvetica Chimica Acta AG, Zürich.

  10. Evaluation of the antimicrobial potential of two flavonoids isolated from limnophila plants.

    Brahmachari, Goutam; Mandal, Narayan C; Jash, Shyamal K; Roy, Rajiv; Mandal, Lalan C; Mukhopadhyay, Arijit; Behera, Biswajit; Majhi, Sasadhar; Mondal, Avijit; Gangopadhyay, Arindam


    The antimicrobial potential of two bioflavonoids, i.e., 5,7-dihydroxy-4',6,8-trimethoxyflavone (1) and 5,6-dihydroxy-4',7,8-trimethoxyflavone (2), isolated from Limnophila heterophylla Benth. and L. indica (Linn.) Druce (Scrophulariaceae), respectively, were evaluated against the microbial strains Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Salmonella typhimurium, Alternaria solani, and Candida albicans. Compounds 1 and 2 exhibited moderate but broad antimicrobial activities against both Gram-positive and Gram-negative bacteria and also against the fungal pathogens. Moreover, the mechanism of action of 1 and 2 on the cellular functions or structures of some of the microorganisms was studied. Compound 1 showed a bactericidal effect against E. coli and S. aureus (MICs of 200 and 250 μg/ml, resp.), while compound 2 was found to effectively kill B. subtilis by cell lysis. The growth of A. solani and C. albicans was inhibited by compounds 1 and 2, respectively. The effects of the flavonoids on the cellular structures and the carbohydrate metabolic pathways were studied by scanning electron microscopy (SEM) of the treated cells and by assessing the specific activity of key enzymes of the pathways, respectively. At sublethal doses, they enhanced the activity of gluconeogenic fructose bisphosphatase, but decreased the activity of phosphofructokinase and isocitrate dehydrogenase, the key enzymes of the EmbdenMeyerhofParnas pathway and the tricarboxylic acid cycle, respectively. Copyright © 2011 Verlag Helvetica Chimica Acta AG, Zürich.

  11. Composition and antimicrobial activity of the essential oils of Laserpitium latifolium L. and L. ochridanum Micevski (Apiaceae).

    Popović, Višnja B; Petrović, Silvana D; Milenković, Marina T; Drobac, Milica M; Couladis, Maria A; Niketić, Marjan S


    The chemical composition and antimicrobial activity of essential oils of Laserpitium latifolium and L. ochridanum were investigated. The essential oils were isolated by steam distillation and characterized by GC-FID and GC/MS analyses. All essential oils were distinguished by high contents of monoterpenes, and α-pinene was the most abundant compound in the essential oils of L. latifolium underground parts and fruits (contents of 44.4 and 44.0%, resp.). The fruit essential oil was also rich in sabinene (26.8%). Regarding the L. ochridanum essential oils, the main constituents were limonene in the fruit oil (57.7%) and sabinene in the herb oil (25.9%). The antimicrobial activity of these essential oils as well as that of L. ochridanum underground parts, whose composition was reported previously, was tested by the broth-microdilution method against four Gram-positive and three Gram-negative bacteria and two Candida albicans strains. Except the L. latifolium underground-parts essential oil, the other investigated oils showed a high antimicrobial potential against Staphylococcus aureus, S. epidermidis, Micrococcus luteus, or Candida albicans (minimal inhibitory concentrations of 13.0-73.0 μg/ml), comparable to or even higher than that of thymol, which was used as reference compound. Copyright © 2015 Verlag Helvetica Chimica Acta AG, Zürich.

  12. Chemical composition and antimicrobial activity of the essential oil from the edible aromatic plant Aristolochia delavayi.

    Li, Zhi-Jian; Njateng, Guy S S; He, Wen-Jia; Zhang, Hong-Xia; Gu, Jian-Long; Chen, Shan-Na; Du, Zhi-Zhi


    The essential oil obtained by hydrodistillation from the aerial parts of Aristolochia delavayi Franch. (Aristolochiaceae), a unique edible aromatic plant consumed by the Nakhi (Naxi) people in Yunnan, China, was investigated using GC/MS analysis. In total, 95 components, representing more than 95% of the oil composition, were identified, and the main constituents found were (E)-dec-2-enal (52.0%), (E)-dodec-2-enal (6.8%), dodecanal (3.35%), heptanal (2.88%), and decanal (2.63%). The essential oil showed strong inhibitory activity (96% reduction) of the production of bacterial volatile sulfide compounds (VSC) by Klebsiella pneumoniae, an effect that was comparable with that of the reference compound citral (91% reduction). Moreover, the antimicrobial activity of the essential oil and the isolated major compound against eight bacterial and six fungal strains were evaluated. The essential oil showed significant antibacterial activity against Providencia stuartii and Escherichia coli, with minimal inhibitory concentrations (MIC) ranging from 3.9 to 62.5 μg/ml. The oil also showed strong inhibitory activity against the fungal strains Trichophyton ajelloi, Trichophyton terrestre, Candida glabrata, Candida guilliermondii, and Cryptococcus neoformans, with MIC values ranging from 3.9 to 31.25 μg/ml, while (E)-dec-2-enal presented a lower antifungal activity than the essential oil. Copyright © 2013 Verlag Helvetica Chimica Acta AG, Zürich.

  13. Composition and antibacterial activity of the essential oils of four commercial grades of Omani luban, the oleo-gum resin of Boswellia sacra FLUECK.

    Al-Saidi, Salim; Rameshkumar, K B; Hisham, Abdulkhader; Sivakumar, Nallusamy; Al-Kindy, Salma


    The essential oil compositions of four botanically certified and commercially available samples of Omani lubans (oleo-gum resins of Boswellia sacra Flueck.), locally known as Hoojri, Najdi, Shathari, and Shaabi in Jibali Arabic, obtained from plants growing in four different geographic locations of the Dhofar region of Oman, were analyzed by GC-FID, GC/MS, and (13) C-NMR spectroscopy. The market price of these four grades of lubans differed considerably, according to their color, clump size, and texture. However, this study revealed that Hoojri, the first grade luban, and Shaabi, the fourth grade luban, which greatly differed in their price, closely resembled each other in their essential oil composition, yield, and physicochemical characteristics, except the color and texture. The composition, yield, and specific rotation of the oils of Najdi and Shathari, the second and the third grade lubans, respectively, were different from those of Hoojri and Shaabi, but they both had high limonene contents. Najdi oil was different from the other three oils in terms of its high myrcene content. α-Pinene was the principal component in all the oils and can be considered as a chemotaxonomical marker that confirms the botanical and geographical source of the resins. All the oils showed pronounced activity against a panel of bacteria, and the trend in their bioactivity and their mode of action are discussed. Copyright © 2012 Verlag Helvetica Chimica Acta AG, Zürich.

  14. Increases in both acute and chronic temperature potentiate tocotrienol concentrations in wild barley at 'Evolution Canyon'.

    Shen, Yu; Lansky, Ephraim; Traber, Maret; Nevo, Eviatar


    Biosynthesis of tocols (vitamin E isoforms) is linked to response to temperature in plants. 'Evolution Canyon', an ecogeographical microcosm extending over an average of 200 meters (range 100-400) wide area in the Carmel Mountains of northern Israel, has been suggested as a model for studying global warming. Both domestic (Hordeum vulgare) and wild (Hordeum spontaneum) barley compared with wheat, oat, corn, rice, and rye show high tocotrienol/tocopherol ratios. Therefore, we hypothesized that tocol distribution might change in response to global warming. α-, β-, γ-, and δ-tocopherol, and α-, β-, γ-, and δ-tocotrienol concentrations were measured in wild barley (H. spontaneum) seeds harvested from the xeric (African) and mesic (European) slopes of Evolution Canyon over a six-year period from 2005-2011. Additionally, we examined seeds from areas contiguous to and distant from the part of the Canyon severely burned during the Carmel Fire of December 2010. Increased α-tocotrienol (pslope in contrast to the cooler 'European' slope, and 3) to propinquity to the fire. The study illustrates the role of α-tocotrienol in both chronic and acute temperature adaptation in wild barley and suggests future research into thermoregulatory mechanisms in plants. Copyright © 2013 Verlag Helvetica Chimica Acta AG, Zürich.

  15. Chemical constituents of Cordia latifolia and their nematicidal activity.

    Begum, Sabira; Perwaiz, Sobiya; Siddiqui, Bina S; Khan, Shazia; Fayyaz, Shahina; Ramzan, Musarrat


    Following nematicidal activity-guided isolation studies on the fruits, bark, and leaves of Cordia latifolia, two new constituents, cordinoic acid (=11-oxours-12-ene-23,28-dioic acid; 1) and cordicilin (=2-{[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}-3-[4-hydroxy-3-(stearoyloxy)phenyl]propanoic acid; 2) were isolated from the stem and leaves, respectively, together with nine known compounds, namely cordioic and cordifolic acid from the stem bark, latifolicin A-D and rosmarinic acid from the fruits, and cordinol and cordicinol from the leaves. Their structures were determined by means of spectroscopic analyses including 1D- and 2D-NMR techniques. The nematicidal activities of these constituents were determined against the root-knot nematode Meloidogyne incognita. Hundred percent mortality was caused by all of these after 72 h at a 0.125% concentration. Compound 1 and cordioic acid were most active and caused 100% mortality after 24 h at a 0.50% concentration. Furthermore, compound 2, the ester of rosemarinic acid, was found to be more active than the free acid. Copyright © 2011 Verlag Helvetica Chimica Acta AG, Zürich.

  16. Thioether profragrances: parameters influencing the performance of precursor-based fragrance delivery in functional perfumery.

    Maddalena, Umberto; Trachsel, Alain; Fankhauser, Peter; Berthier, Damien L; Benczédi, Daniel; Wang, Wei; Xi, Xiujuan; Shen, Youqing; Herrmann, Andreas


    A series of thioether profragrances was prepared by reaction of different sulfanylalkanoates with δ-damascone and tested for their release efficiencies in a fabric-softener and an all-purpose cleaner application. Dynamic headspace analysis on dry cotton and on a ceramic plate revealed that the performance of the different precursors depended on the structure, but also on the particular conditions encountered in different applications. Moreover, profragrances derived from other α,β-unsaturated fragrance aldehydes and ketones were synthesized analogously and evaluated using the same test protocol. Thioethers were found to be suitable precursors to release the corresponding fragrances, but neither the quantity of profragrance deposited from an aqueous environment onto the target surface, nor the amount of fragrance released after deposition could be linearly correlated to the hydrophilicity or hydrophobicity of the compounds. Different sets of compounds were found to be the best performers for different types of applications. Only one of the compounds evaluated in the present work, namely the thiolactic acid derivative of δ-damascone, efficiently released the corresponding fragrance in both of the tested applications. Profragrance development for functional perfumery thus remains a partially empirical endeavour. More knowledge (and control) of the various application conditions are required for an efficient profragrance design. Copyright © 2014 Verlag Helvetica Chimica Acta AG, Zürich.

  17. Occurrence of fatty acid short-chain-alkyl esters in fruits of Celastraceae plants.

    Sidorov, Roman A; Zhukov, Anatoly V; Pchelkin, Vasily P; Vereshchagin, Andrei G; Tsydendambaev, Vladimir D


    Small amounts of a mixture of fatty acid short-chain-alkyl esters (FASCAEs) were obtained from the fruits of twelve plant species of Celastraceae family, and in five of them the FASCAEs were present not only in the arils but also in the seeds. These mixtures contained 32 individual FASCAE species, which formed four separate fractions, viz. FA methyl, ethyl, isopropyl, and butyl esters (FAMEs, FAEEs, FAIPEs, and FABEs, resp.). The FASCAE acyl components included the residues of 16 individual C₁₄-C₂₄ saturated, mono-, di-, and trienoic FAs. Linoleic, oleic, and palmitic acids, and, in some cases, also α-linolenic acid predominated in FAMEs and FAEEs, while myristic acid was predominant in FAIPEs. It can be suggested that, in the fruit arils of some plant species, FAMEs and FAEEs were formed at the expense of a same FA pool characteristic of a given species and were strongly different from FAIPEs and FABEs esters regarding the mechanism of their biosynthesis. However, as a whole, the qualitative and quantitative composition of various FASCAE fractions, as well as their FA composition, varied considerably depending on various factors. Therefore, separate FASCAE fractions seem to be synthesized from different FA pools other than those used for triacylglycerol formation. Copyright © 2013 Verlag Helvetica Chimica Acta AG, Zürich.

  18. Biochemical characterization of Helichrysum italicum (Roth) G.Don subsp. italicum (Asteraceae) from Montenegro: phytochemical screening, chemotaxonomy, and antioxidant properties.

    Kladar, Nebojša V; Anačkov, Goran T; Rat, Milica M; Srđenović, Branislava U; Grujić, Nevena N; Šefer, Emilia I; Božin, Biljana N


    The chemical composition and antioxidant properties of the essential oil and EtOH extract of immortelle (Helichrysum italicum (Roth) G.Don subsp. italicum, Asteraceae) collected in Montenegro were evaluated. The essential oil was characterized by GC/MS analysis, and the content of total phenolics and flavonoids in the EtOH extract was determined using the FolinCiocalteu reagent. The free-radical-scavenging capacity (RSC) of both the essential oil and the EtOH extract was assessed with the 2,2-diphenyl-1-pycrylhydrazyl (DPPH) method. Moreover, the inhibition of hydroxyl radical ((.) OH) generation by the EtOH extract of immortelle was evaluated for the first time here. Neryl acetate (28.2%) and γ-curcumene (18.8%) were the main compounds in the essential oil, followed by neryl propionate (9.1%) and ar-curcumene (8.3%). The chemical composition of the oils of the examined and additional 16 selected Helichrysum italicum taxa described in literature were compared using principal component (PCA) and cluster (CA) analyses. The results of the statistical analyses implied the occurrence of at least four different main and three subchemotypes of essential oils. Considering the antioxidant properties, the EtOH extract of immortelle exhibited similar potential as propyl gallate and quercetin, while the essential oil exhibited relatively weak DPPH(.) -scavenging capacity. Copyright © 2015 Verlag Helvetica Chimica Acta AG, Zürich.

  19. Essential-oil composition of Helichrysum italicum (ROTH) G.DON ssp. italicum from Elba Island (Tuscany, Italy).

    Leonardi, Michele; Ambryszewska, Katarzyna E; Melai, Bernardo; Flamini, Guido; Cioni, Pier Luigi; Parri, Federico; Pistelli, Luisa


    The composition of 21 essential-oil samples isolated from Helichrysum italicum collected in seven locations of Elba Island (Tuscany, Italy), characterized by different soil types, during three different periods (January, May, and October 2010) was determined by GC-FID and GC/EI-MS analyses. In total, 115 components were identified, representing 96.8-99.8% of the oil composition. The oils were characterized by a high content of oxygenated monoterpenes (38.6-62.7%), while monoterpene and sesquiterpene hydrocarbons accounted for 2.3-41.9 and 5.1-20.1% of the identified constituents, respectively. The main oxygenated derivatives were nerol (2.8-12.8%) and its ester derivative neryl acetate (5.6-45.9%). To compare the chemical variability of the species within Elba Island and between the island and other localities within the Mediterranean area, studied previously, multivariate statistical analysis was performed. The results obtained showed a difference in the composition of the essential oils of H. italicum from Elba Island, mainly due to the environment where the plant grows, and, in particular, to the soil type. These hypotheses were further confirmed by the comparison of these oils with essential oils obtained from H. italicum collected on other islands of the Tuscan archipelago. Copyright © 2013 Verlag Helvetica Chimica Acta AG, Zürich.

  20. Extraction of the essential oil from endemic Origanum bilgeri P.H.Davis with two different methods: comparison of the oil composition and antibacterial activity.

    Sözmen, Fazli; Uysal, Burcu; Köse, Elif Odabaş; Aktaş, Ozgür; Cinbilgel, Ilker; Oksal, Birsen S


    The antibacterial activity and chemical composition of the essential oils (EOs) isolated from Origanum bilgeri P.H.Davis by two different extraction methods, i.e., hydrodistillation (HD) and solvent-free microwave extraction (SFME), were examined. This endemic Origanum species had shown very good antibacterial activity. The composition of the O. bilgeri EOs obtained by SFME and HD was investigated by GC/MS analysis. The main components of the oils obtained by both methods were carvacrol (90.20-84.30%), p-cymene (3.40-5.85%), γ-terpinene (0.47-1.20%), and thymol (0.69-1.08%). The EO isolation by SFME offered many important advantages, including a higher extraction yield, a shorter extraction time, and a higher content of the active component carvacrol. The carvacrol-rich oils obtained by both HD and SFME showed a good antibacterial activity. The largest inhibition zones were observed for the O. bilgeri EO obtained by SFME. Our study suggests that O. bilgeri EO has the potential to be used as preventative against bacterial contamination in many foods, instead of the common synthetic antimicrobial products. Copyright © 2012 Verlag Helvetica Chimica Acta AG, Zürich.

  1. Antifungal and Herbicidal Effects of Fruit Essential Oils of Four Myrtus communis Genotypes.

    Kordali, Saban; Usanmaz, Ayse; Cakir, Ahmet; Komaki, Amanmohammad; Ercisli, Sezai


    The chemical composition of the essential oils isolated by hydrodistillation from the fruits of four selected Myrtus communis L. genotypes from Turkey was characterized by GC-FID and GC/MS analyses. 1,8-Cineole (29.20-31.40%), linalool (15.67-19.13%), α-terpineol (8.40-18.43%), α-pinene (6.04-20.71%), and geranyl acetate (3.98-7.54%) were found to be the major constituents of the fruit essential oils of all M. communis genotypes investigated. The oils were characterized by high amounts of oxygenated monoterpenes, representing 73.02-83.83% of the total oil compositions. The results of the fungal growth inhibition assays showed that the oils inhibited the growth of 19 phytopathogenic fungi. However, their antifungal activity was generally lower than that of the commercial pesticide benomyl. The herbicidal effects of the oils on the seed germination and seedling growth of Amaranthus retroflexus L., Chenopodium album L., Cirsium arvense (L.) Scop., Lactuca serriola L., and Rumex crispus L. were also determined. The oils completely or partly inhibited the seed germinations and seedling growths of the plants. The findings of the present study suggest that the M. communis essential oils might have potential to be used as natural herbicides as well as fungicides. Copyright © 2016 Verlag Helvetica Chimica Acta AG, Zürich.

  2. Essential oils in the ranunculaceae family: chemical composition of hydrodistilled oils from Consolida regalis, Delphinium elatum, Nigella hispanica, and N. nigellastrum seeds.

    Kokoska, Ladislav; Urbanova, Klara; Kloucek, Pavel; Nedorostova, Lenka; Polesna, Lucie; Malik, Jan; Jiros, Pavel; Havlik, Jaroslav; Vadlejch, Jaroslav; Valterova, Irena


    In this study, we analyzed the chemical composition of volatile oils hydrodistilled from seeds of Consolida regalis, Delphinium elatum, Nigella hispanica, and N. nigellastrum using GC and GC/MS. In C. regalis, octadecenoic (77.79%) and hexadecanoic acid (8.34%) were the main constituents. Similarly, the oils from D. elatum and N. hispanica seeds consisted chiefly of octadecadienoic (42.83 and 35.58%, resp.), hexadecanoic (23.87 and 28.59%, resp.), and octadecenoic acid (21.67 and 19.76%, resp.). Contrastingly, the monoterpene hydrocarbons α-pinene (34.67%) and β-pinene (36.42%) were the main components of N. nigellastrum essential oil. Our results confirm the presence of essential oils in the family Ranunculaceae and suggest chemotaxonomical relationships within the representatives of the genera Consolida, Delphinium, and Nigella. In addition, the presence of various bioactive constituents such as linoleic acid, (-)-β-pinene, squalene, or carotol in seeds of D. elatum, N. hispanica, and N. nigellastrum indicates a possible industrial use of these plants. Copyright © 2012 Verlag Helvetica Chimica Acta AG, Zürich.

  3. Medicinal Uses, Phytochemistry, and Pharmacology of Origanum onites (L.): A Review.

    Tepe, Bektas; Cakir, Ahmet; Sihoglu Tepe, Arzuhan


    Origanum onites L., known as Turkish oregano, has great traditional, medicinal, preservative, and commercial importance. It is used for the treatment of several kinds of ailments, such as gastrointestinal disorders, diabetes, high cholesterol, leukemia, bronchitis, etc. In this review, traditional use, phytochemistry, and pharmacology of O. onites reported between 1988 and 2014 were discussed. This review was prepared based on literature survey on scientific journals and books from libraries and electronic sources, such as Web of Science, PubMed, Scopus, Google Scholar, etc. All databases were searched up to June 2014. Several different classes of terpenoids, triterpene acids, phenolic acids, hydroquinones, flavonoids, hydrocarbons, sterols, pigments, fatty acids, tocopherols, and inorganic compounds were detected mainly in the aerial parts of this plant. Pharmacological studies revealed that extracts obtained from several solvents and individual compounds exhibited antimicrobial, antiviral, antioxidant, insecticidal, anticancer, hepatoprotective, genotoxic, antidiabetic, cholinesterase inhibitory, anti-inflammatory, analgesic activities, etc. O. onites, in general, exhibited remarkable activity potential in almost all test systems. The results of toxicity studies indicated that O. onites did not show any significant toxicity and mutagenicity on Drosophila and Salmonella. Toxicity of the extracts/essential oils and also individual compounds should be evaluated on mammalian cells to ensure their safety. The bioactivity of individual compounds aside from terpenoids should also be assessed in detail. Additionally, mode of action for the bioactive compounds should be evaluated to understand the complex pharmacological effects of these phytochemicals. © 2016 Verlag Helvetica Chimica Acta AG, Zürich.

  4. Phytotoxic potential of Onopordum acanthium L. (Asteraceae).

    Watanabe, Yusuke; Novaes, Paula; Varela, Rosa M; Molinillo, José M G; Kato-Noguchi, Hisashi; Macías, Francisco A


    Onopordum acanthium L. (Asteraceae) is a plant native to southern Europe and southwestern Asia, but it is invasive in disturbed areas and agricultural fields around the world, causing many agronomic problems by interfering with crops or preventing animals from grazing on pastures. Allelopathy could be one of the reasons that this plant has spread over different continents. The aim of the present study was to bioprospect O. acanthium leaf extracts through the isolation and purification of allelopathic secondary metabolites with phytotoxicity to explain their invasive behavior. Phytotoxic activity was tested using etiolated wheat coleoptiles. The most active extract was selected to perform a bioassay-guided isolation of two flavonoids, pectolarigenin (1) and scutellarein 4'-methyl ether (2), and two sesquiterpene lactones, elemanolide 11(13)-dehydromelitensin β-hydroxyisobutyrate (3) and acanthiolide (4). All compounds were isolated for the first time from O. acanthium, and acanthiolide (4) is described for the first time. Compound 3 strongly inhibited the growth of wheat coleoptiles and 1 showed an intermediate effect. The results indicate that these compounds could contribute to the invasion of O. acanthium in ecological systems and agricultural fields. Copyright © 2014 Verlag Helvetica Chimica Acta AG, Zürich.

  5. Chemical Composition of Ballota macedonica Vandas and Ballota nigra L. ssp. foetida (Vis.) Hayek Essential Oils - The Chemotaxonomic Approach.

    Đorđević, Aleksandra S; Jovanović, Olga P; Zlatković, Bojan K; Stojanović, Gordana S


    The essential oils isolated from fresh aerial parts of Ballota macedonica (two populations) and Ballota nigra ssp. foetida were analyzed by GC and GC/MS. Eighty five components were identified in total; 60 components in B. macedonica oil (population from the Former Yugoslav Republic of Macedonia), 34 components in B. macedonica oil (population from the Republic of Serbia), and 33 components in the oil of B. nigra ssp. foetida accounting for 93.9%, 98.4%, and 95.8% of the total oils, respectively. The most abundant components in B. macedonica oils were carotol (13.7 - 52.1%), germacrene D (8.6 - 24.6%), and (E)-caryophyllene (6.5 - 16.5%), while B. nigra ssp. foetida oil was dominated by (E)-phytol (56.9%), germacrene D (10.0%), and (E)-caryophyllene (4.7%). Multivariate statistical analyses (agglomerative hierarchical cluster analysis and principal component analysis) were used to compare and discuss relationships among Ballota species examined so far based on their volatile profiles. The chemical compositions of B. macedonica essential oils are reported for the first time. © 2016 Verlag Helvetica Chimica Acta AG, Zürich.

  6. Essential-oil composition of Daucus carota ssp. major (Pastinocello Carrot) and nine different commercial varieties of Daucus carota ssp. sativus fruits.

    Flamini, Guido; Cosimi, Elena; Cioni, Pier Luigi; Molfetta, Ilaria; Braca, Alessandra


    The chemical composition of the essential oils obtained by hydrodistillation from the pastinocello carrot, Daucus carota ssp. major (Vis.) Arcang. (flowers and achenes), and from nine different commercial varieties of D. carota L. ssp. sativus (achenes) was investigated by GC/MS analyses. Selective breeding over centuries of a naturally occurring subspecies of the wild carrot, D. carota L. ssp. sativus, has produced the common garden vegetable with reduced bitterness, increased sweetness, and minimized woody core. On the other hand, the cultivation of the pastinocello carrot has been abandoned, even if, recently, there has been renewed interest in the development of this species, which risks genetic erosion. The cultivated carrot (D. carota ssp. sativus) and the pastinocello carrot (D. carota ssp. major) were classified as different subspecies of the same species. This close relationship between the two subspecies urged us to compare the chemical composition of their essential oils, to evaluate the differences. The main essential-oil constituents isolated from the pastinocello fruits were geranyl acetate (34.2%), α-pinene (12.9%), geraniol (6.9%), myrcene (4.7%), epi-α-bisabolol (4.5%), sabinene (3.3%), and limonene (3.0%). The fruit essential oils of the nine commercial varieties of D. carota ssp. sativus were very different from that of pastinocello, as also confirmed by multivariate statistical analyses. Copyright © 2014 Verlag Helvetica Chimica Acta AG, Zürich.

  7. Ethnobotany, chemistry, and biological activities of the genus Tithonia (Asteraceae).

    Chagas-Paula, Daniela A; Oliveira, Rejane B; Rocha, Bruno A; Da Costa, Fernando B


    The genus Tithonia is an important source of diverse natural products, particularly sesquiterpene lactones, diterpenes, and flavonoids. The collected information in this review attempts to summarize the recent developments in the ethnobotany, biological activities, and secondary metabolite chemistry of this genus. More than 100 structures of natural products from Tithonia are reported in this review. The species that has been most investigated in this genus is T. diversifolia, from which ca. 150 compounds were isolated. Biological studies are described to evaluate the anti-inflammatory, analgesic, antimalarial, antiviral, antidiabetic, antidiarrhoeal, antimicrobial, antispasmodic, vasorelaxant, cancer-chemopreventive, cytotoxic, toxicological, bioinsecticide, and repellent activities. A few of these studies have been carried out with isolated compounds from Tithonia species, but the majority has been conducted with different extracts. The relationship between the biological activity and the toxicity of compounds isolated from the plants of this genus as well as T. diversifolia extracts still remains unclear, and mechanisms of action remain to be determined. Copyright © 2012 Verlag Helvetica Chimica Acta AG, Zürich.

  8. Chemical composition and biological activities of Tunisian Cupressus arizonica Greene essential oils.

    Ismail, Amri; Mancini, Emilia; De Martino, Laura; Hamrouni, Lamia; Hanana, Mohsen; Jamoussi, Bassem; Gargouri, Samia; Scognamiglio, Mariarosa; De Feo, Vincenzo


    The chemical composition of the essential oils obtained by hydrodistillation of leaves, stems, and female cones of Cupressus arizonica Greene, grown in Tunisia, was studied by GC-FID and GC/MS analyses. Altogether, 62 compounds were identified, 62 in the leaf oil, 19 in the cone oil, and 24 in the stem oil. The cone and stem oils were mainly composed by monoterpene hydrocarbons (96.6 and 85.2%, resp.). In the leaf oil, the total sesquiterpene fraction constituted 36.1% and that of the monoterpene hydrocarbons 33.8% of the total oil composition. The three oils were evaluated for their in vitro herbicidal activity by determining their influence on the germination and the shoot and root growth of the four weed species Sinapis arvensis L., Lolium rigidum Gaudin, Trifolium campestre Schreb., and Phalaris canariensis L. At the highest doses tested (0.8 and 1.0 mg/ml), the leaf essential oil inhibited either totally or almost completely the seed germination and the shoot and root growth of S. arvensis and T. campestre. The oils were also tested for their antifungal activity; however, their effects on the fungal growth were statistically not significant. Copyright © 2014 Verlag Helvetica Chimica Acta AG, Zürich.

  9. Chemical composition and biological activity of the essential oil of Origanum vulgare ssp. hirtum from different areas in the Southern Apennines (Italy).

    Mancini, Emilia; Camele, Ippolito; Elshafie, Hazem S; De Martino, Laura; Pellegrino, Carlo; Grulova, Daniela; De Feo, Vincenzo


    The chemical composition of the essential oils of Origanum vulgare ssp. hirtum, growing wild in three different localities in the Southern Apennines, was studied by GC-FID and GC/MS analyses. In total, 103 compounds were identified. The oils were mainly composed of phenolic compounds and all oils belonged to the chemotype carvacrol/thymol. The three essential oils were evaluated for their in vitro phytotoxic activity by determining their influence on the germination and initial radicle elongation of Sinapis arvensis L., Phalaris canariensis L., Lepidium sativum L., and Raphanus sativus L. The seed germination and radicle growth were affected in various degrees. Moreover, the antifungal activity of the three essential oils was assayed against three species causing pre- and postharvest fruit decay (Monilinia laxa, M. fructigena, and M. fructicola). At 1000 ppm, the three oils completely inhibited fungal growth. The hemolytic activity of the oils was assayed and showed no effect on the cell membranes of bovine erythrocytes. Copyright © 2014 Verlag Helvetica Chimica Acta AG, Zürich.

  10. Antiproliferative compounds of Cyphostemma greveana from a Madagascar dry forest.

    Cao, Shugeng; Hou, Yanpeng; Brodie, Peggy; Miller, James S; Randrianaivo, Richard; Rakotobe, Etienne; Rasamison, Vincent E; Kingston, David G I


    Bioassay-guided fractionation of the EtOH extracts obtained from a plant identified as Cyphostemma greveana Desc. (Vitaceae) led to the identification of one macrolide, lasiodiplodin (1), three sesquiterpenoids, 12-hydroxy-15-oxoselina-4,11-diene (2), 1β,6α-dihydroxyeudesm-4(15)-ene (3), and (7R*)-opposit-4(15)-ene-1β,7-diol (5), and a new diterpenoid, 16,18-dihydroxykolavenic acid lactone (4). All the isolates were tested against the A2780 human ovarian cancer cell line, and compound 4 and a fraction containing 5 as the major constituent showed antiproliferative activities with IC(50) values of 0.44 μM (0.14 μg/ml) and 0.045 μg/ml, respectively. A partial synthesis of compound 5 was carried out, but the pure synthetic compound was inactive, indicating that the activity of the fraction containing it must be due to a very minor and as yet unidentified substance. Copyright © 2011 Verlag Helvetica Chimica Acta AG, Zürich.

  11. Endophytic Actinobacteria from the Brazilian Medicinal Plant Lychnophora ericoides Mart. and the Biological Potential of Their Secondary Metabolites.

    Conti, Raphael; Chagas, Fernanda Oliveira; Caraballo-Rodriguez, Andrés Mauricio; Melo, Weilan Gomes da Paixão; do Nascimento, Andréa Mendes; Cavalcanti, Bruno Coêlho; de Moraes, Manoel Odorico; Pessoa, Cláudia; Costa-Lotufo, Letícia Veras; Krogh, Renata; Andricopulo, Adriano Defini; Lopes, Norberto Peporine; Pupo, Mônica Tallarico


    Endophytic actinobacteria from the Brazilian medicinal plant Lychnophora ericoides were isolated for the first time, and the biological potential of their secondary metabolites was evaluated. A phylogenic analysis of isolated actinobacteria was accomplished with 16S rRNA gene sequencing, and the predominance of the genus Streptomyces was observed. All strains were cultured on solid rice medium, and ethanol extracts were evaluated with antimicrobial and cytotoxic assays against cancer cell lines. As a result, 92% of the extracts showed a high or moderate activity against at least one pathogenic microbial strain or cancer cell line. Based on the biological and chemical analyses of crude extracts, three endophytic strains were selected for further investigation of their chemical profiles. Sixteen compounds were isolated, and 3-hydroxy-4-methoxybenzamide (9) and 2,3-dihydro-2,2-dimethyl-4(1H)-quinazolinone (15) are reported as natural products for the first time in this study. The biological activity of the pure compounds was also assessed. Compound 15 displayed potent cytotoxic activity against all four tested cancer cell lines. Nocardamine (2) was only moderately active against two cancer cell lines but showed strong activity against Trypanosoma cruzi. Our results show that endophytic actinobacteria from L. ericoides are a promising source of bioactive compounds. © 2016 Verlag Helvetica Chimica Acta AG, Zürich.

  12. 'Yeast mail': a novel Saccharomyces application (NSA) to encrypt messages.

    Rosemeyer, Helmut; Paululat, Achim; Heinisch, Jürgen J


    The universal genetic code is used by all life forms to encode biological information. It can also be used to encrypt semantic messages and convey them within organisms without anyone but the sender and recipient knowing, i.e., as a means of steganography. Several theoretical, but comparatively few experimental, approaches have been dedicated to this subject, so far. Here, we describe an experimental system to stably integrate encrypted messages within the yeast genome using a polymerase chain reaction (PCR)-based, one-step homologous recombination system. Thus, DNA sequences encoding alphabetical and/or numerical information will be inherited by yeast propagation and can be sent in the form of dried yeast. Moreover, due to the availability of triple shuttle vectors, Saccharomyces cerevisiae can also be used as an intermediate construction device for transfer of information to either Drosophila or mammalian cells as steganographic containers. Besides its classical use in alcoholic fermentation and its modern use for heterologous gene expression, we here show that baker's yeast can thus be employed in a novel Saccharomyces application (NSA) as a simple steganographic container to hide and convey messages. Copyright © 2014 Verlag Helvetica Chimica Acta AG, Zürich.

  13. Inoceramid and foraminiferal record and biozonation of the Turonian and Coniacian (Upper Cretaceous) of the Mangyshlak Mts., western Kazakhstan

    Walaszczyk, Ireneusz; Kopaevich, Ludmila F.; Beniamovski, Vladimir N.


    Walaszczyk, I., Kopaevich, L.F. and Beniamovski, V.N. 2013. Inoceramid and foraminiferal record and biozonation of the Turonian and Coniacian (Upper Cretaceous) of the Mangyshlak Mts., western Kazakhstan. Acta Geologica Polonica, 63 (4), 469-487. Warszawa. The Turonian and Coniacian (Upper Cretaceous) of the Mangyshlak Mts., western Kazakhstan, yielded a rich and relatively complete inoceramid bivalve record. The faunas and their succession correspond to those known from central and eastern Europe, allowing the zonation established in the latter areas to be applied in a virtually identical form. The gaps in the record of the group in Mangyshlak stem from the regional hiatuses in the geological record in the area and do not reflect any biogeographical differences between eastern and central-western Europe. Planktonic foraminifera are rare. Four successive interval range zones can be distinguished: in ascending stratigraphic order, the Helvetoglobotrunaca helvetica, Marginotruncaca pseudolinneiana, Marginotruncana coronata, and Concavotruncana concavata zones. Their correlation with the inoceramid zonation and, consequently, with the chronostratigraphic scheme, is demonstrated. The zonation and chronostratigraphic subdivision as applied in Mangyshlak may easily be applied to other areas of the peri-Caspian region (Caucasus, Tuarkyr, Kopet-Dagh, SE margin of the East-European Craton).

  14. Gamma activity and residual power of a shutdown reactor after an irregular operating. Acta code for IBM computer 7094, 360 or CDC 6600; Activite gamma et puissance residuelle d'un reacteur a l'arret apres un fonctionnement irregulier. Programme Acta pour calculateur IBM 7094, 360 ou CDC 6600

    Rafalovitch, A


    the aim of this study is to evaluate the influence of the power variation in time. The calculation method and the associated software are described. The last chapter applied the method to a determined problem. (A.L.B.)

  15. Legibility of Sans Serif Type for Use as Body Copy in Computer Mediated Communication.

    Geske, Joel

    A study examined type legibility on computer screens to determine type styles and type sizes that are most legible. Subjects, 107 college students, tested legibility of Helvetica type in 3 different sizes and 3 different faces. Results indicated no significant differences for legibility of Helvetica 12, 10, and 9 point type in the normal typeface…

  16. Wild Sicilian rosemary: phytochemical and morphological screening and antioxidant activity evaluation of extracts and essential oils.

    Napoli, Edoardo M; Siracusa, Laura; Saija, Antonella; Speciale, Antonio; Trombetta, Domenico; Tuttolomondo, Teresa; La Bella, Salvatore; Licata, Mario; Virga, Giuseppe; Leone, Raffaele; Leto, Claudio; Rubino, Laura; Ruberto, Giuseppe


    To identify the best biotypes, an extensive survey of Sicilian wild rosemary was carried out by collecting 57 samples from various sites, followed by taxonomic characterization from an agronomic perspective. All the biotypes collected were classified as Rosmarinus officinalis L. A cluster analysis based on the morphological characteristics of the plants allowed the division of the biotypes into seven main groups, although the characteristics examined were found to be highly similar and not area-dependent. Moreover, all samples were analyzed for their phytochemical content, applying an extraction protocol to obtain the nonvolatile components and hydrodistillation to collect the essential oils for the volatile components. The extracts were characterized by LC-UV-DAD/ESI-MS, and the essential oils by GC-FID and GC/MS analyses. In the nonvolatile fractions, 18 components were identified, namely, 13 flavones, two organic acids, and three diterpenes. In the volatile fractions, a total of 82 components were found, with as predominant components α-pinene and camphene among the monoterpene hydrocarbons and 1,8-cineole, camphor, borneol, and verbenone among the oxygenated monoterpenes. Cluster analyses were carried out on both phytochemical profiles, allowing the separation of the rosemary samples into different chemical groups. Finally, the total phenol content and the antioxidant activity of the essential oils and extracts were determined with the Folin-Ciocalteu (FC) colorimetric assay, the UV radiation-induced peroxidation in liposomal membranes (UV-IP test), and the scavenging activity of the superoxide radical (O$\\rm{{_{2}^{{^\\cdot} -}}}$). The present study confirmed that the essential oils and organic extracts of the Sicilian rosemary samples analyzed showed a considerable antioxidant/free radical-scavenging activity. Copyright © 2015 Verlag Helvetica Chimica Acta AG, Zürich.

  17. The impact of model peptides on structural and dynamic properties of egg yolk lecithin liposomes - experimental and DFT studies.

    Wałęsa, Roksana; Man, Dariusz; Engel, Grzegorz; Siodłak, Dawid; Kupka, Teobald; Ptak, Tomasz; Broda, Małgorzata A


    Electron spin resonance (ESR), (1) H-NMR, voltage and resistance experiments were performed to explore structural and dynamic changes of Egg Yolk Lecithin (EYL) bilayer upon addition of model peptides. Two of them are phenylalanine (Phe) derivatives, Ac-Phe-NHMe (1) and Ac-Phe-NMe2 (2), and the third one, Ac-(Z)-ΔPhe-NMe2 (3), is a derivative of (Z)-α,β-dehydrophenylalanine. The ESR results revealed that all compounds reduced the fluidity of liposome's membrane, and the highest activity was observed for compound 2 with N-methylated C-terminal amide bond (Ac-Phe-NMe2 ). This compound, being the most hydrophobic, penetrates easily through biological membranes. This was also observed in voltage and resistance studies. (1) H-NMR studies provided a sound evidence on H-bond interactions between the studied diamides and lecithin polar head. The most significant changes in H-atom chemical shifts and spin-lattice relaxation times T1 were observed for compound 1. Our experimental studies were supported by theoretical calculations. Complexes EYLAc-Phe-NMe2 and EYLAc-(Z)-ΔPhe-NMe2 , stabilized by NH⋅⋅⋅O or/and CH⋅⋅⋅O H-bonds were created and optimized at M06-2X/6-31G(d) level of theory in vacuo and in H2 O environment. According to our molecular-modeling studies, the most probable lecithin site of H-bond interaction with studied diamides is the negatively charged O-atom in phosphate group which acts as H-atom acceptor. Moreover, the highest binding energy to hydrocarbon chains were observed in the case of Ac-Phe-NMe2 (2). Copyright © 2015 Verlag Helvetica Chimica Acta AG, Zürich.

  18. Essential-oil composition of the needles collected from natural populations of Macedonian pine (Pinus peuce Griseb.) from the Scardo-Pindic mountain system.

    Nikolić, Biljana; Ristić, Mihailo; Bojović, Srdjan; Matevski, Vlado; Krivošej, Zoran; Marin, Petar D


    The needle-terpene profiles of two natural Pinus peuce populations from the Scardo-Pindic mountain system (Mt. Ošljak and Mt. Pelister) were analyzed. Among the 90 detected compounds, 87 were identified. The dominant constituents were α-pinene (45.5%), germacrene D (11.1%), β-pinene (10.8%), and camphene (10.3%). The following eight additional components were found to be present in medium-to-high amounts (0.5-10%): bornyl acetate (5.0%), β-phellandrene (3.4%), β-caryophyllene (2.9%), β-myrcene (0.9%), germacrene D-4-ol (0.9%), tricyclene (0.7%), (E)-hex-2-enal (0.7%), and bicyclogermacrene (0.6%). Although the general needle-terpene profiles of the populations from Mt. Ošljak and Mt. Pelister were found to be similar to those of the populations from Zeletin, Sjekirica, and Mokra Gora (Dinaric Alps), principle component analysis (PCA) of eight terpenes (α-pinene, β-myrcene, α-terpinolene, bornyl acetate, α-terpinyl acetate, β-caryophyllene, trans-β-farnesene, and germacrene D) in 139 tree samples suggested a divergence between the two population groups, i.e., the samples from the Scardo-Pindic mountain system and those from the Dinaric Alps. Genetic analysis of the β-pinene content demonstrated a partial divergence between the two geographical groups. The profiles of both population groups differed from those published for populations from the Balkan-Rhodope mountains system (literature results), which were characterized by high contents of bornyl acetate and citronellol (Greek populations) or δ-car-3-ene (Bulgarian populations). Copyright © 2014 Verlag Helvetica Chimica Acta AG, Zürich.

  19. The volatile profiles of a rare apple (Malus domestica Borkh.) honey: shikimic acid-pathway derivatives, terpenes, and others.

    Kuś, Piotr Marek; Jerković, Igor; Tuberoso, Carlo Ignazio Giovanni; Šarolić, Mladenka


    The volatile profiles of rare Malus domestica Borkh. honey were investigated for the first time. Two representative samples from Poland (sample I) and Spain (sample II) were selected by pollen analysis (44-45% of Malus spp. pollen) and investigated by GC/FID/MS after headspace solid-phase microextraction (HS-SPME) and ultrasonic solvent extraction (USE). The apple honey is characterized by high percentage of shikimic acid-pathway derivatives, as well as terpenes, norisoprenoids, and some other compounds such as coumaran and methyl 1H-indole-3-acetate. The main compounds of the honey headspace were (sample I; sample II): benzaldehyde (9.4%; 32.1%), benzyl alcohol (0.3%; 14.4%), hotrienol (26.0%, 6.2%), and lilac aldehyde isomers (26.3%; 1.7%), but only Spanish sample contained car-2-en-4-one (10.2%). CH2 Cl2 and pentane/Et2 O 1 : 2 (v/v) were used for USE. The most relevant compounds identified in the extracts were: benzaldehyde (0.9-3.9%), benzoic acid (2.0-11.2%), terpendiol I (0.3-7.4%), coumaran (0.0-2.8%), 2-phenylacetic acid (2.0-26.4%), methyl syringate (3.9-13.1%), vomifoliol (5.0-31.8%), and methyl 1H-indole-3-acetate (1.9-10.2%). Apple honey contained also benzyl alcohol, 2-phenylethanol, (E)-cinnamaldehyde, (E)-cinnamyl alcohol, eugenol, vanillin, and linalool that have been found previously in apple flowers, thus disclosing similarity of both volatile profiles. Copyright © 2013 Verlag Helvetica Chimica Acta AG, Zürich.

  20. Variation in the fatty-acid content in seeds of various black, red, and white currant varieties.

    Šavikin, Katarina P; Ðorđević, Boban S; Ristić, Mihailo S; Krivokuća-Ðokić, Dragana; Pljevljakušić, Dejan S; Vulić, Todor


    Currant seeds, a by-product of juice production, are recognized as a valuable source of oil rich in polyunsaturated fatty acids. We have evaluated 28 currant varieties for their oil content and fatty-acid composition. The oil content in the seeds ranged from 18.2-27.7%, and no statistical difference between varieties of different fruit color were recorded. Furthermore, the estimated oil yields in the field production ranged from 26.4-212.4 kg/ha. The GC and GC/MS chemical profiles of the seed oils extracted from all examined varieties were common for currants. Linoleic acid (LA) was the major component, with contents ranging from 32.7-46.9% of total fatty acids, followed by α-linolenic acid (ALA; 2.9-32.0 %), oleic acid (OA; 9.8-19.9%), γ-linolenic acid (GLA; 3.3-18.5%), palmitic acid (PA; 4.4-8.1%), stearidonic acid (SDA; 2.2-4.7%), and stearic acid (SA; 1.2-2.4%). Quantitative differences in the fatty-acid profiles between varieties of different fruit color were observed. Blackcurrant varieties showed significantly higher contents of LA, GLA, and PA than red and white currant varieties, whereas significantly higher amounts of ALA and OL were detected in the red and white varieties. Cluster analysis based on the chemical oil profiles joined the blackcurrants in one group, while most of the red and white cultivars joined in a second group at the same linkage distance. Copyright © 2013 Verlag Helvetica Chimica Acta AG, Zürich.

  1. Peptaibol, secondary-metabolite, and hydrophobin pattern of commercial biocontrol agents formulated with species of the Trichoderma harzianum complex.

    Degenkolb, Thomas; Fog Nielsen, Kristian; Dieckmann, Ralf; Branco-Rocha, Fabiano; Chaverri, Priscila; Samuels, Gary J; Thrane, Ulf; von Döhren, Hans; Vilcinskas, Andreas; Brückner, Hans


    The production of bioactive polypeptides (peptaibiotics) in vivo is a sophisticated adaptation strategy of both mycoparasitic and saprotrophic Trichoderma species for colonizing and defending their natural habitats. This feature is of major practical importance, as the detection of peptaibiotics in plant-protective Trichoderma species, which are successfully used against economically relevant bacterial and fungal plant pathogens, certainly contributes to a better understanding of these complex antagonistic interactions. We analyzed five commercial biocontrol agents (BCAs), namely Canna(®) , Trichosan(®) , Vitalin(®) , Promot(®) WP, and TrichoMax(®) , formulated with recently described species of the Trichoderma harzianum complex, viz. T. afroharzianum, T. simmonsii, and T. guizhouense. By using the well-established, HPLC/MS-based peptaibiomics approach, it could unequivocally be demonstrated that all of these formulations contained new and recurrent peptaibols, i.e., peptaibiotics carrying an acetylated N-terminus, the C-terminus of which is reduced to a 1,2-amino alcohol. Their chain lengths, including the amino alcohol, were 11, 14, and 18 residues, respectively. Peptaibols were also to be the dominating secondary metabolites in plate cultures of the four strains obtained from four of the Trichoderma- based BCAs, contributing 95% of the UHPLC-UV/VIS peak areas and 99% of the total ion count MS peak area from solid media. Furthermore, species-specific hydrophobins, as well as non-peptaibiotic secondary metabolites, were detected, the latter being known for their antifungal, siderophore, or plant-growth-promoting activities. Notably, none of the isolates produced low-molecular weight mycotoxins. Copyright © 2015 Verlag Helvetica Chimica Acta AG, Zürich.

  2. Melanogenesis-inhibitory activity of aromatic glycosides from the stem bark of Acer buergerianum.

    Akihisa, Toshihiro; Orido, Masashi; Akazawa, Hiroyuki; Takahashi, Akitomo; Yamamoto, Ayako; Ogihara, Eri; Fukatsu, Makoto


    A new benzyl glucoside, 3-O-demethylnikoenoside (1), along with eleven known compounds, including seven aromatic glycosides, 2-8, three lignans, 9-11, and one cyclitol, 12, were isolated from the BuOH-soluble fraction of a MeOH extract of Acer buergerianum stem bark. The structures of the new compound were elucidated on the basis of extensive spectroscopic analyses and comparison with literature. Upon evaluation of compounds 1-12 on melanogenesis in B16 melanoma cells induced with α-melanocyte-stimulating hormone (α-MSH), three compounds, i.e., hovetrichoside B (8), pinoresinol 4-O-β-D-glucopyranoside (9), and pinoresinol 4-O-β-D-apiofuranosyl-(1→2)-β-D-glucopyranoside (10), have been found to exhibit inhibitory effects with 41-49% melanin content compared to the control at 100 μM and low cytotoxicity to the cells (81-92% cell viability at 100 μM). Western blot analysis showed that compound 8 reduced the protein levels of MITF (=microphtalmia-associated transcription factor) and tyrosinase, in a concentration-dependent manner, suggesting that 8 inhibits melanogenesis in α-MSH-stimulated B16 melanoma cells by, at least in part, inhibiting the expression of MITF, followed by decreasing the expression of tyrosinase. On the other hand, upon Western blotting, compound 9 was found to reduce the protein levels of tyrosinase and TRP-2, while it increased MITF and TRP-1 (=tyrosine-related protein 1), in a concentration-dependent manner, indicating that 9 inhibits melanogenesis in α-MSH-stimulated B16 melanoma cells by, at least in part, inhibiting the expression of tyrosinase and TRP-2. Copyright © 2013 Verlag Helvetica Chimica Acta AG, Zürich.

  3. Melanogenesis-inhibitory and cytotoxic activities of diarylheptanoids from Acer nikoense bark and their derivatives.

    Akihisa, Toshihiro; Takeda, Ayano; Akazawa, Hiroyuki; Kikuchi, Takashi; Yokokawa, Satoru; Ukiya, Motohiko; Fukatsu, Makoto; Watanabe, Kensuke


    Nine cyclic diarylheptanoids, 1-9, including two new compounds, i.e., 9-oxoacerogenin A (8) and 9-O-β-D-glucopyranosylacerogenin K (9), along with three acyclic diarylheptanoids, 10-12, and four phenolic compounds, 13-16, were isolated from a MeOH extract of the bark of Acer nikoense (Aceraceae). Acid hydrolysis of 9 yielded acerogenin K (17) and D-glucose. Two of the cyclic diarylheptanoids, acerogenin A (1) and (R)-acerogenin B (5), were converted to their ether and ester derivatives, 18-24 and 27-33, respectively, and to the dehydrated derivatives, 25, 26, 34, and 35. Upon evaluation of compounds 1-16 and 18-35 for their inhibitory activities against melanogenesis in B16 melanoma cells, induced with α-melanocyte-stimulating hormone (α-MSH), eight natural glycosides, i.e., six diarylheptanoid glycosides, 2-4, 6, 9, and 12, and two phenolic glycosides, 15 and 16, exhibited inhibitory activities with 24-61% reduction of melanin content at 100 μM concentration with no or almost no toxicity to the cells (88-106% of cell viability at 100 μM). In addition, when compounds 1-16 and 18-35 were evaluated for cytotoxic activity against human cancer cell lines, two natural acyclic diarylheptanoids, 10 and 11, ten ether and ester derivatives, 18-22 and 27-31, and two dehydrated derivatives, 34 and 35, exhibited potent cytotoxicities against HL60 human leukemia cell line (IC(50) 8.1-19.3 μM), and five compounds, 10, 11, 20, 29, and 30, against CRL1579 human melanoma cell line (IC(50) 10.1-18.4 μM). Copyright © 2012 Verlag Helvetica Chimica Acta AG, Zürich.

  4. Pollen aroma fingerprint of two sunflower (Helianthus annuus L.) genotypes characterized by different pollen colors.

    Bertoli, Alessandra; Fambrini, Marco; Doveri, Silvia; Leonardi, Michele; Pugliesi, Claudio; Pistelli, Luisa


    Samples of fresh pollen grains, collected from capitula in full bloom from two genotypes of sunflower (Helianthus annuus L.) and characterized by a different color, i.e., white-cream (WC) and orange (O), were analyzed by the HS-SPME (headspacesolid phase microextraction)/GC/MS technique. This study defined for the first time the fingerprint of the sunflower pollen, separated from the disc flowers, to define its contribution to the inflorescence aroma. In the GC/MS fingerprints of the WC and O genotypes, 61 and 62 volatile compounds were identified, respectively. Monoterpene hydrocarbons (34% in O vs. 28% in WC) and sesquiterpene hydrocarbons (37% in O vs. 31% in WC) were ubiquitous in all samples analyzed and represented the main chemical classes. α-Pinene (21% in O vs. 20% in WC) and sabinene (11% in O vs. 6% in WC) were the dominant volatiles, but also a full range of aliphatic hydrocarbons and their oxygenated derivatives gave a decisive contribution to the aroma composition (10% in O vs. 12% in WC). In addition, dendrolasin (3% in O vs. 4% in WC) and some minor constituents such as (E)-hex-2-en-1-ol (0.4% in O vs. 0.1% in WC) were pointed out not only for their contribution to the pollen scent, but also for their well-known role in the plant ecological relationships. Having evaluated two pollen morphs with different carotenoid-based colors, the study sought to highlight also the presence of some volatile precursors or derivatives of these pigments in the aroma. However, the pollen aroma of the two selected genotypes made a specific chemical contribution to the sunflower inflorescence scent without any influence on carotenoid derivatives. 2011 Verlag Helvetica Chimica Acta AG, Zürich.

  5. Antitumor effect of the essential oil from leaves of Guatteria pogonopus (Annonaceae).

    do N Fontes, José Eraldo; Ferraz, Rosana P C; Britto, Anny C S; Carvalho, Adriana A; Moraes, Manoel O; Pessoa, Claudia; Costa, Emmanoel V; Bezerra, Daniel P


    Guatteria pogonopus Martius, a plant belonging to the Annonaceae family, is found in the remaining Brazilian Atlantic Forest. In this study, the chemical composition and antitumor effects of the essential oil isolated from leaves of G. pogonopus was investigated. The chemical composition of the oil was determined by GC-FID and GC/MS analyses. The in vitro cytotoxicity was evaluated against three different tumor cell lines (OVCAR-8, NCI-H358M, and PC-3M), and the in vivo antitumor activity was tested in mice bearing sarcoma 180 tumor. A total of 29 compounds was identified and quantified in the oil. The major compounds were γ-patchoulene (13.55%), (E)-caryophyllene (11.36%), β-pinene (10.37%), germacrene D (6.72%), bicyclogermacrene (5.97%), α-pinene (5.33%), and germacrene B (4.69%). The essential oil, but neither (E)-caryophyllene nor β-pinene, displayed in vitro cytotoxicity against all three tumor cell lines tested. The obtained average IC50 values ranged from 3.8 to 20.8 μg/ml. The lowest and highest values were obtained against the NCI-H358M and the OVCAR-8 cell lines, respectively. The in vivo tumor-growth-inhibition rates in the tumor-bearing mice treated with essential oil (50 and 100 mg/kg/d) were 25.3 and 42.6%, respectively. Hence, the essential oil showed significant in vitro and in vivo antitumor activity. Copyright © 2013 Verlag Helvetica Chimica Acta AG, Zürich.

  6. Essential oils of medicinal plants from the central andes of Argentina: chemical composition, and antifungal, antibacterial, and insect-repellent activities.

    Lima, Beatriz; López, Sandra; Luna, Lorena; Agüero, María B; Aragón, Liliana; Tapia, Alejandro; Zacchino, Susana; López, María L; Zygadlo, Julio; Feresin, Gabriela E


    The antifungal, antibacterial, and insect-repellent activities of the essential oils (EOs) of Acantholippia seriphioides, Artemisia mendozana, Gymnophyton polycephalum, Satureja parvifolia, Tagetes mendocina, and Lippia integrifolia, collected in the Central Andes area, province of San Juan, Argentina, were investigated. The dermatophytes Microsporum gypseum, Trichophyton mentagrophytes, and T. rubrum were inhibited by the EOs of G. polycephalum, L. integrifolia, and S. parvifolia, with minimum inhibitory concentrations (MICs) between 31.2 and 1000 μg/ml. Moreover, all EOs presented moderate activity against the bacteria tested, and the L. integrifolia and G. polycephalum EOs showed excellent repellent properties against Triatoma infestans, the Chagas disease vector, with repellency values between 60 and 100%. The A. seriphioides, G. polycephalum, and L. integrifolia EOs, obtained by hydrodistillation, were characterized by GC-FID and GC/MS analyses. The highest number of components (40) was identified in L. integrifolia EO, which, along with that of A. seriphioides, contained important amounts of oxygenated monoterpenes (44.35 and 29.72%, resp.). Thymol (27.61%) and carvacrol (13.24%) were the main components of A. seriphioides EO, and borneol, lippifoli-1(6)-en-5-one, and terpinen-4-ol (>8.5%) were the principal compounds of L. integrifolia EO. These results support the idea that oxygenated monoterpenes are the bioactive fractions of the EOs. Finally, the study shows that these Andean species might be used to treat superficial fungal infections and to improve the local Chagas disease situation by vector-control. Copyright © 2011 Verlag Helvetica Chimica Acta AG, Zürich.

  7. Essential oil of Azorella cryptantha collected in two different locations from San Juan Province, Argentina: chemical variability and anti-insect and antimicrobial activities.

    López, Sandra; Lima, Beatriz; Aragón, Liliana; Espinar, Luis Ariza; Tapia, Alejandro; Zacchino, Susana; Zygadlo, Julio; Feresin, Gabriela Egly; López, María Liza


    The essential oils (EOs) of two populations of Azorella cryptantha (Clos) Reiche, a native species from San Juan Province, were obtained by hydrodistillation in a Clevenger-type apparatus and characterized by GC-FID and GC/MS analyses. The compounds identified amounted to 92.3 and 88.7% of the total oil composition for A. cryptantha from Bauchaceta (Ac-BAU) and Agua Negra (Ac-AN), respectively. The EO composition for the two populations was similar, although with differences in the identity and content of the main compounds and also in the identity of minor components. The main compounds of the Ac-BAU EO were α-pinene, α-thujene, sabinene, δ-cadinene, δ-cadinol, trans-β-guaiene, and τ-muurolol, while α-pinene, α-thujene, β-pinene, γ-cadinene, τ-cadinol, δ-cadinene, τ-muurolol, and a not identified compound were the main constituents of the Ac-AN EO, which also contained 3.0% of oxygenated monoterpenes. The repellent activity on Triatoma infestans nymphs was 100 and 92% for the Ac-AN and Ac-BAU EOs, respectively. Regarding the toxic effects on Ceratitis capitata, the EOs were very active with LD(50) values lower than 11 μg/fly. The dermatophytes Microsporum gypseum, Trichophyton rubrum, and T. mentagrophytes and the bacterial strains Escherichia coli LM(1), E. coli LM(2), and Yersinia enterocolitica PI were more sensitive toward the Ac-AN EO (MIC 125 μg/ml) than toward the Ac-BAU EO. This is the first report on the composition of A. cryptantha EO and its anti-insect and antimicrobial properties. Copyright © 2012 Verlag Helvetica Chimica Acta AG, Zürich.

  8. Plant density-dependent variations in bioactive markers and root yield in Australian-grown Salvia miltiorrhiza Bunge.

    Li, Chun Guang; Sheng, Shu Jun; Pang, Edwin C K; May, Brian; Xue, Charlie Chang Li


    The plant density-dependent variations in the root yield and content, and the yield of biomarkers in Australian grown Salvia miltiorrhiza Bunge, a commonly used Chinese medicinal herb for the treatment of cardiovascular diseases, were investigated in a field trial involving six different plant densities. The key biomarker compounds cryptotanshinone, tanshinone I, tanshinone IIA, and salvianolic acid B were quantified by a validated RP-HPLC method, and the root yields were determined per plant pair or unit area. There were significant variations (pplant densities. Positive linear correlations were observed between the contents of the three tanshinones, whereas negative linear correlations were revealed between the contents of the tanshinones and salvianolic acid B. The highest root yield per plant pair was achieved when the plants were grown at 45×30 cm or 45×40 cm, whereas the highest root production par unit area was obtained for a plant density of 30×30 cm. The highest contents of the three tanshinones and the most abundant production of these tanshinones per unit area were achieved when the plants were grown at 30×30 cm. However, the highest content of salvianolic acid B was found for a density of 45×40 cm, while its highest yield per unit area was obtained for densities of 30×40 cm or 45×30 cm. The findings suggest that the plant density distinctly affects the root yield and content and the yield of tanshinones and salvianolic acid B in Australian grown S. miltiorrhiza, which may be used as a guide for developing optimal agricultural procedures for cultivating this herb. Copyright © 2011 Verlag Helvetica Chimica Acta AG, Zürich.

  9. Activity of Six Essential Oils Extracted from Tunisian Plants against Legionella pneumophila.

    Chaftar, Naouel; Girardot, Marion; Quellard, Nathalie; Labanowski, Jérôme; Ghrairi, Tawfik; Hani, Khaled; Frère, Jacques; Imbert, Christine


    The aim of this study was to investigate the composition of six essential oils extracted from Tunisian plants, i.e., Artemisia herba-alba Asso, Citrus sinensis (L.) Osbeck, Juniperus phoenicea L., Rosmarinus officinalis L., Ruta graveolens L., and Thymus vulgaris L., and to evaluate their activity against Legionella pneumophila (microdilution assays). Eight Legionella pneumophila strains were studied, including the two well-known serogroup 1 Lens and Paris strains as controls and six environmental strains isolated from Tunisian spas belonging to serogroups 1, 4, 5, 6, and 8. The essential oils were generally active against L. pneumophila. The activities of the A. herba-alba, C. sinensis, and R. officinalis essential oils were strain-dependent, whereas those of the J. phoenicea and T. vulgaris oils, showing the highest anti-Legionella activities, with minimum inhibitory concentrations (MICs) lower than 0.03 and lower than or equal to 0.07 mg/ml, respectively, were independent of the strains' serogroup. Moreover, the microorganisms treated with T. vulgaris essential oil were shorter, swollen, and less electron-dense compared to the untreated controls. Isoborneol (20.91%), (1S)-α-pinene (18.30%) β-phellandrene (8.08%), α-campholenal (7.91%), and α-phellandrene (7.58%) were the major components isolated from the J. phoenicea oil, while carvacrol (88.50%) was the main compound of the T. vulgaris oil, followed by p-cymene (7.86%). This study highlighted the potential interest of some essential oils extracted from Tunisian plants as biocides to prevent the Legionella risk. Copyright © 2015 Verlag Helvetica Chimica Acta AG, Zürich.

  10. Rubrolides as model for the development of new lactones and their aza analogs as potential photosynthesis inhibitors.

    Pereira, Ulisses A; Barbosa, Luiz C A; Demuner, Antônio J; Silva, Antônio A; Bertazzini, Michele; Forlani, Giuseppe


    Natural phytotoxins and their synthetic analogs are a potential source of new bioactive compounds for agriculture. Analogs of rubrolides, a class of γ-alkylidene-γ-lactones isolated from different ascidians, have been shown to interfere with the photosynthetic electron-transport chain, yet their activity needs to be improved. With this aim, ten 5-aryl-6-benzyl-4-bromopyridazin-3(2H)-ones were prepared in yields ranging from 44 to 88% by reaction of their correspondent γ-alkylidene-γ-lactones with NH2 NH2 . The structures of these rubrolide analogs were determined by (1) H- and (13) C-NMR, 2D-NMR (COSY and HETCOR), NOE difference, and MS techniques. These compounds were evaluated for their abilities of interfering with the light-driven reduction of ferricyanide by isolated spinach chloroplasts. Lactones with electron-withdrawing substituents in the para-position of the benzylidene ring were the most effective inhibitors. Characterization of the activity of 11b/11b' suggested a mechanism based on the interaction with the plastoquinone binding site of photosystem II. Addition of several compounds to the culture medium of a cyanobacterial model strain was found to inhibit algal growth. However, the relative effectiveness was not consistent with their activity in vitro, suggesting the occurrence of multiple targets and/or detoxyfication mechanisms. Indeed, the compounds showed differential effects on the heterotrophic growth of some crop species, Cucumis sativus and Sorghum bicolor. Pyridazin-3(2H)-ones 12e, 12i, and 12j, which have been found poorly active against the photosynthetic electron transport, were the most effective in inhibiting the growth of some weeds, Ipomoea grandifolia and Brachiaria decumbens, under greenhouse conditions. Copyright © 2015 Verlag Helvetica Chimica Acta AG, Zürich.

  11. Carotenoid-cleavage activities of crude enzymes from Pandanous amryllifolius.

    Ningrum, Andriati; Schreiner, Matthias


    Carotenoid degradation products, known as norisoprenoids, are aroma-impact compounds in several plants. Pandan wangi is a common name of the shrub Pandanus amaryllifolius. The genus name 'Pandanus' is derived from the Indonesian name of the tree, pandan. In Indonesia, the leaves from the plant are used for several purposes, e.g., as natural colorants and flavor, and as traditional treatments. The aim of this study was to determine the cleavage of β-carotene and β-apo-8'-carotenal by carotenoid-cleavage enzymes isolated from pandan leaves, to investigate dependencies of the enzymatic activities on temperature and pH, to determine the enzymatic reaction products by using Headspace Solid Phase Microextraction Gas Chromatography/Mass Spectrophotometry (HS-SPME GC/MS), and to investigate the influence of heat treatment and addition of crude enzyme on formation of norisoprenoids. Crude enzymes from pandan leaves showed higher activity against β-carotene than β-apo-8'-carotenal. The optimum temperature of crude enzymes was 70°, while the optimum pH value was 6. We identified β-ionone as the major volatile reaction product from the incubations of two different carotenoid substrates, β-carotene and β-apo-8'-carotenal. Several treatments, e.g., heat treatment and addition of crude enzymes in pandan leaves contributed to the norisoprenoid content. Our findings revealed that the crude enzymes from pandan leaves with carotenoid-cleavage activity might provide a potential application, especially for biocatalysis, in natural-flavor industry. Copyright © 2014 Verlag Helvetica Chimica Acta AG, Zürich.

  12. Phytotoxic Effects and Phytochemical Fingerprinting of Hydrodistilled Oil, Enriched Fractions, and Isolated Compounds Obtained from Cryptocarya massoy (Oken) Kosterm. Bark.

    Rolli, Enrico; Marieschi, Matteo; Maietti, Silvia; Guerrini, Alessandra; Grandini, Alessandro; Sacchetti, Gianni; Bruni, Renato


    The hydrodistilled oil of Cryptocarya massoy bark was characterized by GC-FID and GC/MS analyses, allowing the identification of unusual C10 massoia lactone (3, 56.2%), C12 massoia lactone (4, 16.5%), benzyl benzoate (1, 12.7%), C8 massoia lactone (3.4%), δ-decalactone (5, 1.5%), and benzyl salicylate (2, 1.8%) as main constituents. The phytotoxic activities of the oil, three enriched fractions (lactone-rich, ester-rich, and sesquiterpene-rich), and four constituents (compounds 1, 2, 5, and δ-dodecalactone (6)) against Lycopersicon esculentum and Cucumis sativus seeds and seedlings were screened. At a concentration of 1000 μl/l, the essential oil and the massoia lactone-rich fraction caused a complete inhibition of the germination of both seeds, and, when applied on tomato plantlets, they induced an 85 and 100% dieback, respectively. These performances exceeded those of the well-known phytotoxic essential oils of Syzygium aromaticum and Cymbopogon citratus, already used in commercial products for the weed and pest management. The same substances were also evaluated against four phytopathogenic bacteria and ten phytopathogenic fungi, providing EC50 values against the most susceptible strains in the 100-500 μl/l range for the essential oil and in the 10-50 μl/l range for compound 6 and the lactone-rich fraction. The phytotoxic behavior was related mainly to massoia lactones and benzyl esters, while a greater amount of 6 may infer a good activity against some phytopathogenic fungi. Further investigations of these secondary metabolites are warranted, to evaluate their use as natural herbicides. Copyright © 2016 Verlag Helvetica Chimica Acta AG, Zürich.

  13. Actas del Simposio-Taller sobre estrategias y herramientas para el aprendizaje y la evaluación: Jenui 2013: Castellón, 9 de julio de 2013

    Marqués Andrés, Mercedes; Badía Contelles, José Manuel; Barrachina Mir, Sergio; López, David; Vaquerizo, Belén


    El curso 2012-2013 se ha puesto en marcha la asignatura Dirección estratégica de las tecnologías de la información perteneciente al Máster Universitario en Ingeniería Informática de la Escuela Politécnica Superior de la Universidad de Alicante. Basándonos en el principio predicar con el ejemplo, se utilizan las técnicas y los principios de la dirección estratégica y se aplican al diseño y la ejecución de la propuesta docente de la asignatura. Además, en su diseño se han utilizado una diversid...

  14. Relationships between body mass index and short-circuit current in human duodenal and colonic mucosal biopsies. Osbak PS, Bindslev N, Hansen MB. Acta Physiol (Oxf). 2011 Jan;201(1):47-53

    Osbak, Philip Samuel; Bindslev, Niels; Berner-Hansen, Mark


    Aim: Retrospectively, to investigate the relationship between body mass index (BMI) and basal electrogenic transport as measured by short-circuit current (SCC) in human duodenal and colonic mucosal biopsies. Methods: The study included biopsies from mucosa of normal appearance in the sigmoid colon...... and >25 kg m)2). Statistical significance was assessed by the unpaired t-test or Wilcoxon rank-sum test. Correlation coefficients were calculated by Pearson product moment correlation. Results: In colonic biopsies, basal SCC (mean standard deviation) was significantly higher in 59 biopsies from 30...

  15. Actas de la 4th mesa redonda sobre investigacion en "Lenguas Extranjeras" en la Universidad Autonoma Metropolitana 1996. (Proceedings from the 4th Roundtable on Investigation in Foreign Languages in the Autonomous Metropolitan University 1996).

    Zoreda, Margaret Lee, Comp.; Diop, Mamoudou Si, Comp.; Vivaldo Lima, Javier, Comp.

    The articles included in this volume were selected as exemplary papers from the conference in Mexico. The goal of the forum was to provide an opportunity for researchers from the three branches of the Universidad Autonoma Metropolitana (UAM) to meet and discuss research projects currently in progress at the university. The works presented here…

  16. Corrigendum to "Synthesis and spectral characterization of new homologous 1,3,5-triaryl-2-pyrazolines: Influence of alkyloxy chain length on fluorescence" [Spectrochim. Acta Part A: Mol. Biomol. Spectrosc. 133 (2014) 182-189

    Abbas, Asghar; Hussain, Safdar; Hafeez, Noureen; Naseer, Muhammad Moazzam


    The authors regret to inform that the affiliation of one of the authors, namely, Noureen Hafeez has been written as Department of Forensic Medicine & Toxicology, Rawalpindi Institute of Health Sciences (RIHS), Bahria University, Islamabad, Pakistan in the published article. The correct address is shown above.

  17. Coping with Social Change: Programs That Work. Proceedings of a Conference (Acapulco, Mexico, June 1989) = Como enfrentarse al cambio social: programas eficaces. Actas de uno Conferencia (Acapulco, Mexico, Junio de 1989).

    Hoskins, Irene, Ed.

    Written in English and Spanish, this document contains the proceedings of the 14th International Congress of Gerontology on concerns about the impact of rapid social change on the well-being of older women and families in Latin American and the Caribbean and about effective programs that address the needs of the older populations. The first…

  18. Experimental evidence for two distinct deeply supercooled liquid states of water – Response to “Comment on ‘Water's second glass transition”’, by G.P. Johari, Thermochim. Acta (2015)

    Stern, J.; Seidl, M. [Institute of Physical Chemistry, University of Innsbruck, 6020 Innsbruck (Austria); Gainaru, C. [Fakultät Physik, Technische Universität Dortmund, 44221 Dortmund (Germany); Fuentes-Landete, V.; Amann-Winkel, K.; Handle, P.H. [Institute of Physical Chemistry, University of Innsbruck, 6020 Innsbruck (Austria); Köster, K.W.; Nelson, H. [Fakultät Physik, Technische Universität Dortmund, 44221 Dortmund (Germany); Böhmer, R., E-mail: [Fakultät Physik, Technische Universität Dortmund, 44221 Dortmund (Germany); Loerting, T., E-mail: [Institute of Physical Chemistry, University of Innsbruck, 6020 Innsbruck (Austria)


    Highlights: • Two samples of amorphous ices quench-recovered from 140 K to 0.07 GPa are compared. • Calorimetry, X-ray diffraction, dielectric spectroscopy and volumetry are employed. • The two samples are distinct and cannot both be termed “pressure-densified glassy water”. • One route of preparation leads to high- (HDA), and the other to low-density amorphous ice (LDA). • Two distinct glass transitions are observed and interpreted to indicate two liquid H{sub 2}O phases. - Abstract: Recently, our earlier data which led us to conclude that deeply supercooled water displays a second glass transition (Amann-Winkel et al., 2013) was reinterpreted (Johari, 2015). In particular, the increase in heat capacity observed for high-density amorphous ice (HDA) samples at 116 K was reinterpreted to indicate sub-T{sub g} features of low-density amorphous ice's (LDA's) glass transition. We reply to the criticism in detail and report an experiment triggered by the comment on our work. This experiment unequivocally confirms our original interpretation of the observations and reinforces the case for water's second glass transition, its polyamorphism, and the observation of two distinct ultraviscous states of water differing by about 25% in density.

  19. Vārda brīvības un intelektuālā īpašuma aizsardzības līdzsvarošana ACTA

    Bulzgis, Raivo


    Attīstoties intelektuālā īpašuma tiesībām un tā tiesiskajam regulējumam, tiek ierobežotas personu tiesības uz vārda brīvību. Ņemot vērā, ka tiek pieņemts jauns starptautiskais līgums šajā jomā, tad šī darba tēma ir aktuāla visā pasaulē. Darba mērķis ir noskaidrot, intelektuālā īpašuma un vārda brīvības robežas. Izvirzītā mērķa realizēšanai darba autors izvirzīja vairākus uzdevumus: izpētīt jēdzienus “vārda brīvība” un “intelektuālais īpašums”, analizēt šo jēdzienu robežas, kā arī iepazī...

  20. The corrected version of the article 'Physics in 1900' printed in Acta Physica Polonica B31, 179-196 (2000), Proceedings of the 26. Mazurian Lakes School of Physics 'Nuclear Physics at the Turn of the Century'

    Wroblewski, A.K.


    The state of physics in 1900 is reviewed by making use of the documents of that year, in particular the material of the 1 st International Congress of Physics. Contrary to simplified accounts which portrait 1900 as the year of revolutionary transition from classical to quantum physics it is shown that almost all physicists at that time were satisfied with classical physics and were actively enriching and expanding it. (author)

  1. Use of QSAR validation principles to enhance predictive approaches in the US EPA ECOSAR model

    The US EPA Office of Pollution Prevention and Toxics (OPPT) is responsible for implementing the Toxic Substances Control Act (TSCA). TSCA is the US law that regulates industrial chemicals in the US and OPPT evaluates both new chemicals entering commerce, as well as those chemica...

  2. Preparation of α-deuterated L-amino acids using E.coli cells containing tryptophanase

    Faleev, N.G.; Ruvinov, S.B.; Saporovskaya, M.B.; Belikov, V.M.; Zakomyrdina, L.N.; Sakharova, I.S.; Torchinskij, Yu.M.


    Method for preparation of a series of α-deuterated L-amino acids of high optical purity with quantitative chemica yield, suing stereospecific isotopic exchange in D 2 O under the effect of E.coli cells with high tryptophanase activity was developed

  3. Enhancement of developmental toxicity effects of chemicals by gestational stress. A review

    Hougaard, Karin S; Hansen, Åse Marie


    Risk assessment of developmental toxicants is almost exclusively based on single chemicals studied in animals under controlled experimental conditions, as to reduce stress. Although humans may be exposed simultaneously to numerous hazards, little is known about the interaction of prenatal chemica...

  4. Incident reporting and analysis in maintenance and application of safety management tools

    Schaaf, van der T.W.; Martin, H.


    The research programme described in this paper focus es on the human component of system failure in general, and more specifically on the design and implementation of information systems for registration and analysis of so-called near misses in the chemica/ and steel industry. lts goal is to enhance

  5. Absorption and distribution of C14-labeled tetramine in relation to its possible use in animal damage control

    M.A. Radwan


    Tetramethylenedisulphotetramine (tetramine) is an extremely toxic chemicaI (Hagen 1950).' Shortly after its discovery in Germany (Hecht and Henecka 1949L it was introduced in the United States and found useful as an experimental seed protectant in reforestation by direct seeding (Spencer 1954). The first indication of tetramine's systemic characteristics was...

  6. Fundamental toxicology

    Royal Society of Chemistry (Great Britain); Worth, Howard G. J; Duffus, John H


    ... regulations for the Control of Substances Hazardous to Health (COSHH). At the international level, the International Programme on Chemical Safety (IPCS), a joint activity of the World Health Organisation (WHO), the United Nations Environmental Programme (UNEP) and the International Labour Organisation (ILO) have published many valuable documents on chemica...

  7. The effect of temperature and methanol–water mixture on pressurized hot water extraction (PHWE) of anti-HIV analogoues from Bidens pilosa

    Gbashi, S


    Full Text Available . Bairwa K, Kumar R, Sharma RJ, Roy RK (2010) An updated review on Bidens pilosa L. Der Pharma Chemica 2:325–337 3. Arthur GD, Naidoo KK, Coopoosamy RM (2012) Bidens pilosa L.: agricul- tural and pharmaceutical importance. J Med Plants Res 6:3282–3287 4...

  8. Low Temperature Curing of Hydrogen Silsesquioxane Surface Coatings for Corrosion Protection of Aluminum

    Lampert, Felix; Jensen, Annemette Hindhede; Møller, Per


    Hydrogen Silsesquioxane (HSQ) has shown to be a promising precursor for corrosion protective glass coatings for metallic substrates due to the excellent barrier properties of the films, especially in the application of protective coatings for aluminum in the automotive industry where high chemica...

  9. Preparation of. alpha. -deuterated L-amino acids using E. coli cells containing tryptophanase. Poluchenie. alpha. -dejterirovannykh L-aminokislot s ispol'zovaniem kletok E. coli, soderzhashchikh triptofanazy

    Faleev, N G; Ruvinov, S B; Saporovskaya, M B; Belikov, V M; Zakomyrdina, L N; Sakharova, I S; Torchinskij, Yu M [AN SSSR, Moscow (USSR). Inst. Ehlementoorganicheskikh Soedinenij AN SSSR, Moscow (USSR). Inst. Molekulyarnoj Biologii AN SSSR, Moscow (USSR)


    Method for preparation of a series of {alpha}-deuterated L-amino acids of high optical purity with quantitative chemica yield, suing stereospecific isotopic exchange in D{sub 2}O under the effect of E.coli cells with high tryptophanase activity was developed.

  10. Derechos Educacionales de los Padres: Una Explicacion de los Procedimientos de Seguridad para los Padres de Ninos con Discapacidades. Bajo la Clausula del Acta de Educacion para Individuos con Discapacidades (IDEA) y las Reglas para la Administracion del Acta de Educacion para Ninos Excepcionales (Educational Rights of Parents: An Explanation of Procedural Safeguards Available to Parents of Children with Disabilities. Under Provisions of the Individuals with Disabilities Education Act (IDEA) and the Rules for the Administration of the Exceptional Children's Educational Act [ECEA]).

    Mountain Plains Regional Resource Center, Des Moines, IA.

    This pamphlet, in Spanish, describes Colorado parents' educational rights under federal and state special education rules and regulations. It addresses: (1) free appropriate public education and termination of services; (2) required prior notice to parents if there is a proposed change or refusal to change a child's special education program; (3)…

  11. Flåtbårne infektioner i Danmark

    Jensen, Bo Bødker; Ocias, Lukas Frans; Andersen, Nanna Skaarup


    The castor bean tick, Ixodes ricinus, is common in woodlands in most of Denmark. Besides Borrelia burgdorferi, it can harbour a number of pathogenic microorganisms such as tick-borne encephalitis virus, Anaplasma phagocytophilum, Rickettsia helvetica, Francisella tularensis, Candidatus Neoehrlichia...

  12. Dicty_cDB: Contig-U15903-1 [Dicty_cDB

    Full Text Available 2 ( EU435859 ) Dicranosepsis distincta voucher su18 cytochrome o... 34 5.2 2 ( EU435856 ) Dicranosepsis cf....34 5.2 2 ( EF216252 ) Drosophila helvetica voucher YNU00006 cytochrome ... 34 5.2

  13. 12C. Environmental Chemical Exposure: Endocrine System Effects and Clinical Health Implications

    Cohen, Aly


    Focus Area: Pediatrics Every day, the United States alone uses or imports about 42 million pounds of synthetic chemicals. There are more than 84 000 compounds approved for commercial use in the United States, most of which have never been tested for toxicity. A 2011 policy statement issued by the American Academy of Pediatrics acknowledges that the large quantities of chemicals that enter commerce could be harmful to children's health and development. The contribution of many of these chemica...

  14. Resilience of SAR11 bacteria to rapid acidification in the high latitude open ocean

    Hartmann, Manuela; Hill, Polly G.; Tynan, Eithne; Achterberg, Eric P.; Leakey, Raymond J. G.; Zubkov, Mikhail V.


    Ubiquitous SAR11 Alphaproteobacteria numerically dominate marine planktonic communities. Because they are excruciatingly difficult to cultivate, there is comparatively little known about their physiology and metabolic responses to long- and short- term environmental changes. As surface oceans take up anthropogenic, atmospheric CO2, the consequential process of ocean acidification could affect the global biogeochemical significance of SAR11. Shipping accidents or inadvertent release of chemica...

  15. Avaliação dos parâmetros de qualidade de chips em relação com diferentes variedades de plátano (Musa paradisíaca L.)

    Lucas A, Juan Carlos; Quintero C, Víctor Dumar; Vasco Leal, José Fernando; Mosquera Artamonov, José Daniel


    Introduction. Plantain crops occupy one of the widest planted areas in Colombia and can be found all over the country, but research contributions are not usually addressed to the knowledge of the raw product as a basic or secondary raw material to obtain a processed product. Objectives. Seven varieties of in fresh plantain were physically evaluated and so was their relationship with quality parameters for finished products. Materials and methods. A physical- chemica...

  16. Molecular Targets and Synaptic Effects of Carbamates, Organophosphates, Oximes, and Pyridiniums: Implications for Prophylaxis and Therapy of Organophosphate Toxicity


    placed on bipolar conversion of ACh to H z02 which is detected electro- stimulating electrodes. The exposed nerve and muscle chemica !4y with a platinum...transient and regulated by outward currents carried chiefly by po- the delayed components can he separated pharma . tassiuini ions, represented by a...coriex cultunred ii’ sc ruin-icc. I’ll viuiology and Phanrijciulagr (if Epittqnoogeiic P/:naomte- cheimically dcrilled incdiumni. Der -. Blaini Res

  17. Microcapsules Filled with a Palm Oil-Based Alkyd as Healing Agent for Epoxy Matrix

    Nurshafiza Shahabudin; Rosiyah Yahya; Seng Neon Gan


    One of the approaches to prolong the service lifespan of polymeric material is the development of self-healing ability by means of embedded microcapsules containing a healing agent. In this work, poly(melamine-urea-formaldehyde) (PMUF) microcapsules containing a palm oil-based alkyd were produced by polymerization of melamine resin, urea and formaldehyde that encapsulated droplets of the suspended alkyd particles. A series of spherical and free-flowing microcapsules were obtained. The chemica...

  18. Thermalisation of a two-dimensional photonic gas in a 'white-wall' photon box

    Klaers, Jan; Vewinger, Frank; Weitz, Martin


    Bose-Einstein condensation, the macroscopic accumulation of bosonic particles in the energetic ground state below a critical temperature, has been demonstrated in several physical systems. The perhaps best known example of a bosonic gas, blackbody radiation, however exhibits no Bose-Einstein condensation at low temperatures. Instead of collectively occupying the lowest energy mode, the photons disappear in the cavity walls when the temperature is lowered - corresponding to a vanishing chemica...

  19. A chemical library to screen protein and protein-ligand crystallization using a versatile microfluidic platform

    Gerard , Charline ,; Ferry , Gilles; Vuillard , Laurent ,; Boutin , Jean ,; Ferte , Nathalie ,; Grossier , Romain ,; Candoni , Nadine ,; Veesler , Stéphane ,


    Here, we describe a plug-and-play microfluidic platform, suitable for protein crystallization. The droplet factory is designed to generate hundreds of droplets as small as a few nanoliters (2 to 10nL) for screening and optimization of crystallization conditions. Commercially-available microfluidic junctions and tubing are combined to create the appropriate geometry. In addition, a " chemical library " is produced in tubing. The microfluidic geometry for a " crystallization agent-based chemica...

  20. A novel fiber-based adsorbent technology

    Reynolds, T.A. [Chemica Technologies, Inc., Bend, OR (United States)


    In this Phase I Small Business Innovation Research program, Chemica Technologies, Inc. is developing an economical, robust, fiber-based adsorbent technology for removal of heavy metals from contaminated water. The key innovation is the development of regenerable adsorbent fibers and adsorbent fiber cloths that have high capacity and selectivity for heavy metals and are chemically robust. The process has the potential for widespread use at DOE facilities, mining operations, and the chemical process industry.

  1. Composition and Antimicrobial Activity of Euphrasia rostkoviana Hayne Essential Oil

    Novy, Pavel; Davidova, Hana; Serrano-Rojero, Cecilia Suqued; Rondevaldova, Johana; Pulkrabek, Josef; Kokoska, Ladislav


    Eyebright, Euphrasia rostkoviana Hayne (Scrophulariaceae), is a medicinal plant traditionally used in Europe for the treatment of various health disorders, especially as eyewash to treat eye ailments such as conjunctivitis and blepharitis that can be associated with bacterial infections. Some Euphrasia species have been previously reported to contain essential oil. However, the composition and bioactivity of E. rostkoviana oil are unknown. Therefore, in this study, we investigated the chemica...

  2. Preparation of a three-dimensional extracellular matrix by decellularization of rabbit livers

    Nari, Gustavo A.; Cid, Mariana; Comín, Romina; Reyna, Laura; Juri, Gustavo; Taborda, Ricardo; Salvatierra, Nancy A.


    Introduction: the availability of transplantable livers is not sufficient to fulfill the current demand for grafts, with the search for therapeutic alternatives having generated different lines of research, one of which is the use of decellularized three-dimensional biological matrices and subsequent cell seeding to obtain a functional organ. Objective: to produce a decellularization protocol from rabbit liver to generate a three-dimensional matrix. Methods: a combination of physical, chemica...

  3. Environmental and seasonal impacts on the chemical composition of Satureja horvatii Šilić (Lamiaceae) essential oils.

    Lakušić, Branislava; Ristić, Mihailo; Slavkovska, Violeta; Milenković, Marina; Lakušić, Dmitar


    The chemical composition of the essential oils of Satureja horvatii Šilić from two natural habitats (Mt. Orjen and Mt. Lovćen in Montenegro) and from cultivated plants (Belgrade, Serbia) were characterized. For the latter, plants from the locus classicus, i.e., Orjenske Lokve (Mt. Orjen), were transferred to Belgrade and, after three years of cultivation, the chemical composition of their essential oils at different phenological stages was analyzed. The essential oils were obtained from the aerial parts of the plants by hydrodistillation and analyzed by GC and GC/MS. The yields and chemical compositions of the S. horvatii oils showed significant differences between the plants collected in the natural habitats and those from cultivation, as well as between the plants at different phenological stages. In the populations from the natural habitats, growing in Mediterranean conditions, the most abundant oil constituents were the phenols thymol (63.7% in the samples from Mt. Orjen) or carvacrol (68.1% in the samples from Mt. Lovćen), while the oils from the cultivated plants (Belgrade), growing in continental conditions, were dominated by linalool (up to 65.8 and 55.9% in average). The basic characteristics of the essential oil from plants at the early phenological stage (before flowering) were high percentages of linalool (37.4%), thymol (27.3%), and carvacrol (12.2%). At the stage of flowering, the percentage of linalool (56.6-57.5%) increased, while those of thymol (15.5-15.8%) and carvacrol (1.4-1.5%) significantly decreased. The essential oil of plants in the full stage of fruiting was characterized by the domination of linalool (58.4 and 65.8%) and lower percentages of thymol (7.6 and 1.3%) and carvacrol (0.7 and 0.1%). In conclusion, the oil composition of S. horvatii was found to depend on the pedoclimatic conditions of the habitat and the phenological stage of the plants. Copyright © 2011 Verlag Helvetica Chimica Acta AG, Zürich.

  4. On the terminal homologation of physiologically active peptides as a means of increasing stability in human serum--neurotensin, opiorphin, B27-KK10 epitope, NPY.

    Seebach, Dieter; Lukaszuk, Aneta; Patora-Komisarska, Krystyna; Podwysocka, Dominika; Gardiner, James; Ebert, Marc-Olivier; Reubi, Jean Claude; Cescato, Renzo; Waser, Beatrice; Gmeiner, Peter; Hübner, Harald; Rougeot, Catherine


    The terminal homologation by CH(2) insertion into the peptides mentioned in the title is described. This involves replacement of the N-terminal amino acid residue by a β(2) - and of the C-terminal amino acid residue by a β(3) -homo-amino acid moiety (β(2) hXaa and β(3) hXaa, resp.; Fig. 1). In this way, the structure of the peptide chain from the N-terminal to the C-terminal stereogenic center is identical, and the modified peptide is protected against cleavage by exopeptidases (Figs. 2 and 3). Neurotensin (NT; 1) and its C-terminal fragment NT(8-13) are ligands of the G-protein-coupled receptors (GPCR) NT1, NT2, NT3, and NT analogs are promising tools to be used in cancer diagnostics and therapy. The affinities of homologated NT analogs, 2b-2e, for NT1 and NT2 receptors were determined by using cell homogenates and tumor tissues (Table 1); in the latter experiments, the affinities for the NT1 receptor are more or less the same as those of NT (0.5-1.3 vs. 0.6 nM). At the same time, one of the homologated NT analogs, 2c, survives in human plasma for 7 days at 37° (Fig. 6). An NMR analysis of NT(8-13) (Tables 2 and 4, and Fig. 8) reveals that this N-terminal NT fragment folds to a turn in CD(3) OH. - In the case of the human analgesic opiorphin (3a), a pentapeptide, and of the HIV-derived B27-KK10 (4a), a decapeptide, terminal homologation (→3b and 4b, resp.) led to a 7- and 70-fold half-life increase in plasma (Fig. 9). With N-terminally homologated NPY, 5c, we were not able to determine serum stability; the peptide consisting of 36 amino acid residues is subject to cleavage by endopetidases. Three of the homologated compounds, 2b, 2c, and 5c, were shown to be agonists (Fig. 7 and 11). A comparison of terminal homologation with other stability-increasing terminal modifications of peptides is performed (Fig. 5), and possible applications of the neurotensin analogs, described herein, are discussed. Copyright © 2011 Verlag Helvetica Chimica

  5. Proceedings of the 3. Regional Meeting on Radiological and Nuclear Safety. Radiological protection in Latin America and the Caribbean. Vol. 1,2; Actas del 3. Congreso Regional sobre Seguridad Radiologica y Nuclear. Proteccion Radiologica en America Latina y el Caribe. Vol. 1,2



    Two volumes contain more than 183 complete papers presented during the Third Regional Meeting on Radiological Protection and Nuclear Safety held on 23-27 October, 1995 in Cusco-Peru. Latin american specialist talk about nuclear safety and radiological protection, radiation natural exposure, biological effect of radiation, radiotherapy and medical radiological safety, radiological safety in industry and research. Also we deal with subjects related to radiological safety of nuclear and radioactive facilities, radioactive waste management, radioactive material transport, environmental radiological monitoring program, radiological emergency and accidents, instruments and dosimetry, basic safety standards of protection against radiation.

  6. DOI: 10.4025/actascibiolsci.v33i3.8011 Acta Scientiarum. Biological Sciences Maringá, v. 33, n. 3, p. 239-246, 2011 Acute inflammatory response in Nile tilapia fed probiotic Lactobacillus plantarum in the diet = Resposta inflamatória aguda em tilápia do Nilo alimentada com probiótico, Lactobacillus plantarum na dieta

    Geovana Dotta


    Full Text Available The present study evaluated the acute inflammatory response induced bycarrageenin (500 £gg injected in the swim bladder of Nile tilapia, after fed or not probiotic supplemented diet. Fifty four fish were distributed in six treatments and three replicates: Group A: Fish fed unsupplemented diet: 0.5 mL saline-injected fish; fish injected with 500 £gg carrageenin diluted in 0.5 mL saline; Non-injected. Group B: Fish fed probiotic supplemented diet: saline-injected fish; carrageenin-injected fish; Non-injected. Fifteen days after feeding the fish were injected with carrageenin or saline. After six hours, inflammatory exudate was collected, as well as the blood for hematocrit, red blood cell (RBC and white blood cell (WBC counts, differential count of leucocytes and phagocytic activity in the blood. Supplementation with probiotic did not influence the RBC, hematocrit and the numbers of lymphocytes and basophils in the blood. The number of neutrophils was significantly higher in supplemented fish injected with carrageenin. Glucose concentration in supplemented and non-injected fish was higher than that observed in the saline injected ones. Probiotic potentialized the migration of cells to the inflammatory focus in the animals injected with the carrageenin irritant. In fish injected with saline and carrageenin occurred the greatest phagocytic activity in the blood in relation to those treatments.Este trabalho avaliou a resposta inflamatoria aguda induzida por injecao de carragenina (500 ƒÝg na bexiga natatoria de tilapia do Nilo suplementada ou nao com probiotico na racao. Cinquenta e quatro animais foram distribuidos em seis tratamentos com tres repeticoes: Grupo A: peixes alimentados com racao naosuplementada: Controle (injecao de 0,5 mL de solucao salina esteril; Carragenina (injecao de500 £gg de carragenina; Nao-injetada. Grupo B: peixes alimentados com racao suplementada com probiotico: Controle; Carragenina; Nao-injetada. Apos 15 dias de alimentacao foi injetado carragenina ou salina. Apos 6h, realizou-se a coleta de exsudato e sangue para determinacao do hematocrito, contagens totais de eritrocitos, leucocitos, contagem diferencial de leucocitos e atividade fagocitaria no sangue. A suplementacao com probiotico na racao nao influenciou o numero total de eritrocitos, o hematocrito e os numeros de linfocitos e basofilos no sangue dos animais. O numero de neutrofilos foi maior nos peixes suplementados com probiotico einjetados com carragenina. A glicose nos peixes suplementados com probiotico nao-injetados foi maior do que nos injetados com salina. A suplementacao com probiotico potencializou a migracao de celulas para o foco inflamatorio nos injetados com o flogogeno carragenina. Empeixes injetados com salina e carragenina, ocorreu maior atividade fagocitaria no sangue em relacao aos demais tratamentos.

  7. Guia del Proceso del IFSP de Colorado: Conexiones para la Ninez Temprana, Iniciativa Infantil de Colorado Parte C del Acta de Educacion para Individuos con Desabilidades (Colorado Guidelines for the IFSP Process: Early Childhood Connections, Colorado's Infant/Toddler Initiative for Part C of the Individuals with Disabilities Education Act).

    Miller, Jerri; Petersen, Sandy

    This booklet for Spanish-speaking parents of young children with disabilities describes Colorado's Individualized Family Service Plan (IFSP) process. It explains guidelines, shares family stories and reflections for families and care providers, and the describes the values that drive the IFSP process in Colorado. Information is provided on…


    Said , Sylvère


    The concern of this body of work is the mechanism of dégradation of impregnated polypropylène film capacitors in an oxygen blanket. Tins study is carried out on plane électrode capacitor models with expérimental parameters (AC electrical field in the range 66 V/um-200 V/pm, oxygen blanket, température 80°C) which hâve enabled us to obtain results in good agreement with industrial capacitor behaviour.Capacitor ageing is mainly assessed by its mean life-time and the change in the physio-chemica...

  9. D2B, a new high resolution neutron powder diffractometer at ILL Grenoble

    Hewat, A.W.


    Applications of high resolution neutron powder diffraction to materials science have grown rapidly in the past 10 years, with the development of Rietveld methods of profile refinement, and new high resolution diffractometers and multidetectors. Materials studied range from catalysts to zeolites, and from battery electrodes to prestressed superconducting wires. Although the techniques have now been adapted for X-ray and synchrotron radiation, neutron powder diffraction retains unique advantages. In this paper we describe the design and first test measurements on the latest high resolution powder diffractometer D2B at ILL Grenoble. A review of the applications is published in Chemica Scripta (1986). (author) 9 refs., 6 figs., 2 tabs

  10. European Science Notes, Volume 39, Number 5.


    c The most-studied polymers thus far have a pharma -rdy"imir’ properties in the been those based on acrylarnide (Davis, thorpy r-gime. Cnt ro Ileo del...scientific endeavor, wensi- .......................... 1,921 der the high quality, hicht(P’fo’ manufacturing output from this ’ t’( i mphasis on air force...rot only in intformat ion and comiuni cation tioth- nology, but also :n rather Lb. i - areas of physico- chemica I rsea r ch. On the other hand, a U’ss

  11. Proceedings of the Annual Chemical Defense Bioscience Review (5th) Held at Columbia, Maryland on 29-31 May 1985. Appendix 1


    and Meyer, H.G. Life Sciences 36: 1715-1720, 1985. 3. Van Helden, H.P.M.; van der Well, H.J.; and Wolthius, O.L. TNO Technical Report # MBL-1984-3...SYNTHESIS IN OUR LABORA- TORY BY STANDARD LITERATURE PROCEDURES OR AS A GIFT FROM PHARMA - CEUTICAL MANUFACTURERS THAT MARKET THE DRUGS, ALL OF THE COM- POUNDS...Rosenberry, T. L. Croatia Chemica Acto 1975, _7 235 Incursion of other steps then general base catalysis, such as confor-:ational changes, in rate

  12. Proceedings of the American Society for Composites: Biotechnology Aided Synthesis of Aerospace Composite Resins Held in Dayton, Ohio 25-26 August 1987.


    of Shell Chemical Company. EPI-REZ is a trademark of Intere, Inc ARALDITE is a tradenmark of Ciba Geigy Corporation. DER . is a trademark of Dow...scupe of materials--such as pharma - ceuticals, foodstuffs, and commodity chemicals--that can be obtained through its use. Advances in the has sarc int-i- 5 in widel1y diVerse areas: 1. Developjment -rrmettl-1n e’ s for spec’ialty chemica I F r ) w (’_irbelyd ra r - 2. Pioneerinq thef

  13. Register of Planned Emergency Producers.



  14. Chemical bond fundamental aspects of chemical bonding

    Frenking, Gernot


    This is the perfect complement to ""Chemical Bonding - Across the Periodic Table"" by the same editors, who are two of the top scientists working on this topic, each with extensive experience and important connections within the community. The resulting book is a unique overview of the different approaches used for describing a chemical bond, including molecular-orbital based, valence-bond based, ELF, AIM and density-functional based methods. It takes into account the many developments that have taken place in the field over the past few decades due to the rapid advances in quantum chemica

  15. The application of plant biotechnology for non-food uses: The case ...



    Oct 24, 2011 ... in China has more diverse applications for non-food uses and environmental sustainability. This paper ..... pollen distribution on mulberry leaves near rice fields. Acta .Ecol. Sin. .... resistant plants on pollinating bees. Acta Ecol.

  16. 76 FR 19684 - Automotive Fuel Ratings Certification and Posting


    ... Helvetica Black font but rather allow any legible block type font because Microsoft Word does not offer... content, size, color, and font of the label. \\9\\ ASTM International, formerly known as the American... type of biomass-based diesel.\\36\\ The commenters asserted that disclosing the presence of renewable...

  17. Spotted fever group rickettsiae detected in immature stages of ticks parasitizing on Iberian endemic lizard Lacerta schreiberi Bedriaga, 1878

    Kubelová, M.; Papoušek, I.; Bělohlávek, T.; Goüy de Bellocq, Joëlle; Baird, Stuart J. E.; Široký, P.


    Roč. 6, č. 6 (2015), s. 711-714 ISSN 1877-959X Institutional support: RVO:68081766 Keywords : Spotted fever group rickettsiae * Rickettsia monacensis * Rickettsia helvetica * Ixodes ricinus * Lacerta schreiberi Subject RIV: GJ - Animal Vermins ; Diseases, Veterinary Medicine Impact factor: 2.690, year: 2015

  18. Rickettsiae in questing Ixodes ricinus ticks in the Czech Republic

    Venclíková, Kristýna; Rudolf, Ivo; Mendel, Jan; Betášová, Lenka; Hubálek, Zdeněk


    Roč. 5, č. 2 (2014), s. 135-138 ISSN 1877-959X Institutional support: RVO:68081766 Keywords : Ixodes ricinus * Anaplasma phagocytophilum * Rickettsia spp. * Rickettsia helvetica * Rickettsia monacensis * Candidatus Neoehrlichia mikurensis Subject RIV: EE - Microbiology, Virology Impact factor: 2.718, year: 2014

  19. Serological and molecular evidence for spotted fever group Rickettsia and Borrelia burgdorferi sensu lato co-infections in The Netherlands

    Koetsveld, Joris; Tijsse-Klasen, Ellen; Herremans, Tineke; Hovius, Joppe W. R.; Sprong, Hein


    Only a few reported cases indicate that Rickettsia helvetica and Rickettsia monacensis can cause disease in humans. Exposure to these two spotted fever group (SFG) rickettsiae occurs through bites of Ixodes ricinus, also the primary vector of Lyme borreliosis in Europe. To date, it is unclear how

  20. Is sarcoidosis a rickettsiosis? An archival study

    Svendsen, Claus Bo; Milman, Nils; Andersen, Claus B


    Based on earlier research, Rickettsia helvetica could possibly be involved in the pathogenesis of sarcoidosis. Rickettsiae are transmitted to humans by a tick vector, Ixodes ricinus; this tick is highly prevalent in Northern Europe. We aimed to investigate the association between evidence...... of rickettsiae and sarcoidosis in histological samples....

  1. Tick-borne zoonotic pathogens in ticks feeding on the common nightingale including a novel strain of Rickettsia sp

    Dubská, L.; Literák, I.; Kverek, P.; Roubalová, Eva; Kocianova, E.; Taragelova, V.


    Roč. 3, č. 4 (2012), s. 265-268 ISSN 1877-959X Institutional support: RVO:60077344 Keywords : tick * Ixodes ricinus * Borrelia garinii * Anaplasma phagocytophilum * Rickettsia helvetica * Babesia sp. EU1 * Common nightingale Subject RIV: GJ - Animal Vermins ; Diseases, Veterinary Medicine Impact factor: 2.353, year: 2012

  2. Boekbespreking

    Meijden, van der Ruud


    H. Haeupler & T. Muer, Bildatlas der Farn- und Blütenpflanzen Deutschlands, Eugen Ulmer Verlag, Stuttgart. 2000, 759 pag., >4000 kleurenfoto’s + detailtekeningen en -foto’s, ƒ 185, ISBN 3-8001-3364-4. Dit magistrale fotoboek overtreft de toch ook prachtige Flora Helvetica (zie Gorteria 22: 170).

  3. Effect of Typeface on Iconic Storage Capacity.

    Hoffman, Valerie

    Various aspects of iconic memory have been studied in the past. Two tachistoscopic experiments were conducted to examine how legibility of a stimulus affects a subject's ability to recall brief visual presentation. The studies used letter arrays set in four different typefaces (Helvetica, Cooper Black Outline, Electronic, Old English). In the…

  4. Is sarcoidosis a rickettsiosis? An archival study

    Svendsen, Claus Bo; Milman, Nils; Andersen, Claus B


    Based on earlier research, Rickettsia helvetica could possibly be involved in the pathogenesis of sarcoidosis. Rickettsiae are transmitted to humans by a tick vector, Ixodes ricinus; this tick is highly prevalent in Northern Europe. We aimed to investigate the association between evidence...

  5. Bibliographic Index to the Plague (1965-1970)


    Entomology Review Acta Pathol. et ’Microbiol. Scmad. Acta Pathologica and Microbiologica Scandinavica (Copenhagen) Acta Trop. Acta Tronica ( Basil ) Amer...Basel - New York) Pediatrics Pediatrics (Springfield) Pest Control Pest Control (Cleveland) Pesticides Pesticides Pharmn. :tg. Pharmaceutical Journal...Institutions from Inst. 1964-68 and Pros. for Their 1964-1968 and the Prospects for Their Fut. Act. Future Activities . (Theses of Reports to the

  6. What Will They Learn? 2012-13. A Survey of Core Requirements at Our Nation's Colleges and Universities

    Kempson, Lauri; Bako, Tom; Lewin, Greg


    The American Council of Trustees and Alumni (ACTA) has released "What Will They Learn? 2012-13," the fourth edition, evaluating the general education requirements at 1,070 colleges and universities. Unlike other college rankings, ACTA does not consider an institution's wealth, prestige, or popularity. Rather, ACTA rates institutions…

  7. Změny využití krajiny u jihomoravských vodních nádrží

    Havlíček, M.; Halas, Petr; Lacina, Jan; Mlejnková, H.


    Roč. 2014, č. 108 (2014), s. 25-35 ISSN 1805-921X Institutional support: RVO:68145535 Keywords : land use * water reservoir * vegetation Subject RIV: DE - Earth Magnetism, Geodesy, Geography

  8. The Geology of Yemen: An Annotated Bibliography of Yemen’s Geology, Geography and Earth Science


    Sobreexplotacion De Acuiferos; Actas; Ponencias, Comunicaciones y Resumenes De Posters. XXIII International Congress on Aquifer Overexploitation...Overexploitation of Groundwater Resources in Wadi Hadramaut; XXIII Congreso Internacional Sobreexplotacion De Acuiferos; Actas; Ponencias, Comunicaciones Acuiferos; Actas; Ponencias, Comunicaciones y Resumenes De Posters. XXIII International Congress on Aquifer Overexploitation; Proceedings

  9. Bibliography of Soviet Laser Developments, Number 90, July-August 1987


    Acta physica polonica . Series A AUONA Acta Universitatis Palackianae Olomucensis. Facultas rerum naturalium. Physica (Olomouc) AVMEB Avtometriya (CTC...translation available) AENGA Atomnaya energiya (CTC) AKZHA Akusticheskiy zhurnal (CTC) APSVC Acta physica slovaca ARAKB Archiwum akustyki (Warsaw) ATPLB...khimiya, mekhanika (Moskva) PRTEA Pribory i tekhnika eksperimenta (CTC) 136 PSSAB Physica status solidi (A). Applied Research (GDR) PSSBB Physica status

  10. Using Python to Program LEGO MINDSTORMS® Robots: The PyNXC Project


    Full Text Available

    Helvetica; margin: 0px">Helvetica, sans-serif" size="2" class="Apple-style-span">Helvetica" size="3" class="Apple-style-span">

    Helvetica, sans-serif" size="2" class="Apple-style-span">Helvetica" size="3" class="Apple-style-span">

    LEGO MINDSTORMS® NXT (Lego Group, 2006 is a perfect platform for introducing programming concepts, and is generally targeted toward children from age 8-14.  The language which ships with the MINDSTORMS®, called NXTg, is a graphical language based on LabVIEW (Jeff Kodosky, 2010.  Although there is much value in graphical languages, such as LabVIEW, a text-based alternative can be targeted at an older audiences and serve as part of a more general introduction to modern computing.  Other languages, such as NXC (Not Exactly C (Hansen, 2010 and PbLua (Hempel, 2010, fit this description.  Here we introduce PyNXC, a subset of the Python language which can be used to program the NXT MINDSTORMS®.  We present results using PyNXC, comparisons with other languages, and some challenges and future possible extensions.


  11. Creativity and Democratic Governance. Adult Learning: A Strategic Choice. Proceedings of the ICAE World Assembly (6th, Ocho Rios, Jamaica, August 9-12, 2001) = Creativite et Gouvernance Democratique. L'apprentissage des Adultes: Un Choix Strategique. Actes de la Assemblee Mondiale du CIEA (6th, Ocho Rios, Jamaique, 9 au 12 aout 2001) = Creatividad y Gobernabilidad Democratica. Educacion de Adultos: Una Eleccion Estrategica. Actas de la Asamblea Mundial del ICAE (6th, Ocho Rios, Jamaica, Agosto 9-12, 2001).

    Dobson, Stephan, Ed.

    This document contains information from and about a world assembly on creativity and democratic governance in adult learning that was held by the International Council for Adult Education (ICAE) and its partner organizations in the Caribbean. The proceedings begin with English, French, and Spanish translations of the address…

  12. People’s Republic of China Scientific Abstracts No. 180


    translations of these articles. CONTENTS PAGE CHIH-WU HSUEH-PAO [ACTA BOTANICA SINICA] No 1, March 1977 1 K’UN-CH’UNG HSUEH-PAO [ACTA ENTOMOLOGICA...March 1977. 28 TUNG-WU HSUEH-PAO [ACTA ZOOLOGICA SINICA] No 2, June.1977 41 a - [III - CC - 70 S § T] ACTA BOTANICA SINICA AUTHOR...HSUEH-PAO [ACTA BOTANICA SINICA] in Chinese Vol 19 No 1, Mar 77 pp 7-10 TEXT OF ENGLISH ABSTRACT: In 1964, we some young teachers and students in

  13. Prevalence and diversity of human pathogenic rickettsiae in urban versus rural habitats, Hungary.

    Szekeres, Sándor; Docters van Leeuwen, Arieke; Rigó, Krisztina; Jablonszky, Mónika; Majoros, Gábor; Sprong, Hein; Földvári, Gábor


    Tick-borne rickettsioses belong to the important emerging infectious diseases worldwide. We investigated the potential human exposure to rickettsiae by determining their presence in questing ticks collected in an urban park of Budapest and a popular hunting and recreational forest area in southern Hungary. Differences were found in the infectious risk between the two habitats. Rickettsia monacensis and Rickettsia helvetica were identified with sequencing in questing Ixodes ricinus, the only ticks species collected in the city park. Female I. ricinus had a particularly high prevalence of R. helvetica (45%). Tick community was more diverse in the rural habitat with Dermacentor reticulatus ticks having especially high percentage (58%) of Rickettsia raoultii infection. We conclude that despite the distinct eco-epidemiological traits, the risk (hazard and exposure) of acquiring human pathogenic rickettsial infections in both the urban and the rural study sites exists.

  14. Pengaruh Tipografi pada Era Massimo Vignelli terhadap Tipografi Michael Bierut

    Irwan Harnoko


    Full Text Available Massimo Vignelli is a senior graphic designer lived in New York, as a vocal modernism against post-modernism. His statement firmly opposing post-modernism in several occasions: interview in Helvetica the movie, typeradio, talkshow, and some articles in Looking Closer or AIGA Journal. Graphic design works of Massimo Vignelli reflected his characteristic, which is firmly choosing typeface. Typefaces of Vignelly are around 5 typefaces: Bodoni, Helvetica, Times Roman, Century, and Futura. The article uses formal analysis method. The writers collected materials about Michael Bierut, Massimo VIgnelli and Tibor Kalman from books and websites. The writers compare the typeface opinion of Massimo Vignelli (modernism designer, Michael Bierut designer (transition era designer from modernism to post-modernism, and Tibor Kalman (a designer in A Century of Graphic Design, as the influencer of Bierut’s betrayal over Vignelli. 

  15. High-throughput screening of tick-borne pathogens in Europe

    Michelet, Lorraine; Delannoy, Sabine; Devillers, Elodie


    was conducted on 7050 Ixodes ricinus nymphs collected from France, Denmark, and the Netherlands using a powerful new high-throughput approach. This advanced methodology permitted the simultaneous detection of 25 bacterial, and 12 parasitic species (including; Borrelia, Anaplasma, Ehrlichia, Rickettsia......, Bartonella, Candidatus Neoehrlichia, Coxiella, Francisella, Babesia, and Theileria genus) across 94 samples. We successfully determined the prevalence of expected (Borrelia burgdorferi sensu lato, Anaplasma phagocytophilum, Rickettsia helvetica, Candidatus Neoehrlichia mikurensis, Babesia divergens, Babesia...

  16. Genetic variability of Rickettsia spp. in Ixodes persulcatus ticks from continental and island areas of the Russian Far East.

    Igolkina, Y; Bondarenko, E; Rar, V; Epikhina, T; Vysochina, N; Pukhovskaya, N; Tikunov, A; Ivanov, L; Golovljova, I; Ivanov, М; Tikunova, N


    Rickettsia spp. are intracellular Gram-negative bacteria transmitted by arthropods. Two potentially pathogenic rickettsiae, Candidatus Rickettsia tarasevichiae and Rickettsia helvetica, have been found in unfed adult Ixodes persulcatus ticks. The aim of this study was to assess the prevalence and genetic variability of Rickettsia spp. in I. persulcatus ticks collected from different locations in the Russian Far East. In total, 604 adult I. persulcatus ticks collected from four sites in the Khabarovsk Territory (continental area) and one site in Sakhalin Island were examined for the presence of Rickettsia spp. by real-time PCR. Nested PCR with species-specific primers and sequencing were used for genotyping of revealed rickettsiae. The overall prevalence of Rickettsia spp. in ticks collected in different sites varied from 67.9 to 90.7%. However, the proportion of different Rickettsia species observed in ticks from Sakhalin Island significantly differed from that in ticks from the Khabarovsk Territory. In Sakhalin Island, R. helvetica prevailed in examined ticks, while Candidatus R. tarasevichiae was predominant in the Khabarovsk Territory. For gltA and ompB gene fragments, the sequences obtained for Candidatus R. tarasevichiae from all studied sites were identical to each other and to the known sequences of this species. According to sequence analysis of gltA, оmpB and sca4 genes, R. helvetica isolates from Sakhalin Island and the Khabarovsk Territory were identical to each other, but they differed from R. helvetica from other regions and from those found in other tick species. For the first time, DNA of pathogenic Rickettsia heilongjiangensis was detected in I. persulcatus ticks in two sites from the Khabarovsk Territory. The gltA, ompA and оmpB gene sequences of R. heilongjiangensis were identical to or had solitary mismatches with the corresponding sequences of R. heilongjiangensis found in other tick species. Copyright © 2016 Elsevier GmbH. All rights

  17. Instrumentation Analysis: An Automated Method for Producing Numeric Abstractions of Heap-Manipulating Programs


    Arbib and Suad Alagic. Proof rules for gotos. Acta Informatica , pages 139–148, 1979. 6.3 T. Ball, R. Majumdar, T. Millstein, and S. Rajamani...Press, January 1999. ISBN 0262032708. 3, 3.1, 3.3 323 B Bibliography M. Clint and C.A.R. Hoare. Program proving: Jumps and functions. Acta Informatica ...Goto statements: Semantics and deduction systems. Acta Informatica , pages 385–424, 1981. 6.3 324 B Bibliography Alain Deutsch. Interprocedural may

  18. The Structure and Infrastructure of Chinese Science and Technology


    Series C-Life Sciences 38 Theoretical And Applied Genetics 32 Journal Of Forensic Sciences 31 Febs Letters 31 Acta Botanica Sinica 30 Protein...A1-18 – Journals Containing Most Crops Papers JOURNAL #PAPERS Acta Botanica Sinica 233 Chinese Science Bulletin 128 Theoretical And Applied...physiological VEGETABLES; QUALITY; ACTA BOTANICA SINICA BIOLOGICAL & MEDICAL SCIENCES STRESS PHYSIOLOGY 6.3 5 2 19 16 212 To extract v Investiga


    Ministerio de Salud


    Accident: Analysis and Prevention. New York. Bimestral
    Acodal. Bogotá. Irregular
    Acta Chirurgica Scandinavica. Estocolmo. 8 números al año
    Acta Psiquiátrica y Psicológica de América Latina. Buenos Aires. Trimestral
    Age. Nebrasca. Trimestral
    Age and Ageing. Londres. Bimestral
    Ageing International. Washington. Trimestral
    Alcoholism. Zagreb. Semestral
    AMC.Acta Médica Colombiana. Trimestral &l...

  20. Hybné síly dlouhodobých proměn industrializované krajiny (Případová studie Hrušov)

    Martinát, Stanislav; Dvořák, Petr; Klusáček, Petr; Kunc, Josef; Havlíček, M.


    Roč. 106, č. 106 (2014), s. 35-44 ISSN 1805-921X R&D Projects: GA MŠk EE2.3.20.0025 Institutional support: RVO:68145535 Keywords : Hrušov * Ostrava * industrial landscape * deindustrialisation * brownfields Subject RIV: DE - Earth Magnetism, Geodesy, Geography

  1. Bibliography of Soviet Developments in Superconductivity, January 1975 - June 1976


    superconductors. Acta physica pclonica, A 47, no. 3, 1975, 339-346. 182. Trifan, A. T. Effects of pressure and paramagnetic impurity on...FTT FZh GiA GiK IAN Arm IAN Az Avtomatika i telemekha-iika Acta physic a polonica Akademiya nauk Armyanskoy SSR. Doklady Akademiya nauk...thickness of thin cylindrical superconducting In films near T . Acta physlca polonlca, A47, ID. 3, 1975, 323-327. c I I I I I t t I

  2. Investigation of Diode Pumped Alkali Laser Atmospheric Transmission Using Tunable Diode Laser Absorption Spectroscopy


    Optics Letters, 28(23):2336–2338, 2003. 48. Lavan, M. “High Energy Laser Systems for Short Range Defense”. Acta Physica Polonica -Series A General diode laser spectrometer for the remote sensing of vehicle emissions”. Spec- trochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 60...P. “A review of recent advances in semiconductor laser based gas mon- itors”. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 54

  3. Endogenous Protection Derived from Activin A/Smads Transduction Loop Stimulated via Ischemic Injury in PC12 Cells

    Mang, Jing; Mei, Chun-Li; Wang, Jiao-Qi; Li, Zong-Shu; Chu, Ting-Ting; He, Jin-Ting; Xu, Zhong-Xin


    Activin A (ActA), a member of transforming growth factor-beta (TGF-b) super- family, affects many cellular processes, including ischemic stroke. Though the neuroprotective effects of exogenous ActA on oxygen-glucose deprivation (OGD) injury have already been reported by us, the endogenous role of ActA remains poorly understood. To further define the role and mechanism of endogenous ActA and its signaling in response to acute ischemic damage, we used an OGD model in PC12 cells to simulate isch...

  4. Research Investigation Directed Toward Extending the Useful Range of the Electromagnetic Spectrum.


    Rubaszewska, and E. Kirkor-Kaminska, Acta Physica Polonica A 54, 767 (1978). (3) W. Rettig, J. Luminescence 26, 21 (1980). (4) W. Rettig and E. Lippert...J. W. Llnnett, Proc. Roy. Soc. 156A, 108 (1936). (9) A. Terenin and N. Prlleshajewa, Acta Physlcochim. I, 759 (1935). (10) C. John, P. Chandra, and...R. J. Capwell, Spec. Acta 27A, 1113 (1971). (4) F. A. Miller and J. A. Wolanin, Spec. Acta 31A, 1427 (1975). (5) J. M. Preses, R. E. Weston, Jr

  5. Looduslikult kestliku ja inimlähedase elu otsingud / Martin Mölder

    Mölder, Martin, 1983-


    Raamatuarvustus: Ökokogukonnad retoorikas ja praktikas : elustiilide uurimused / toimetanud Airi-Alina Allaste. Tallinn : Tallinna Ülikooli Kirjastus, 2011. (Acta Universitatis Tallinnensis. Socialia)


    Renato de Mello Prado


    Full Text Available Slag is a calcium silicate and silicon source, whose corrective action on soil is similar to the limestone one. Despite its corrective and fertilizing potential, there is little information about its effects on soil chemical attributes. The study evaluated the effects of the slag, limestone, and urea application on the chemical attributes of a Brazilian Oxisol cultivated with rice. The treatments consisted of two corrective agents sources (limestone and slag, with three doses (1.3 g dm-3, 2.6 g dm-3, and 5,2 g dm-3; three N doses (80 mg dm-3, 160 mg dm-3, and 320 mg dm-3, applied as urea; and a control, arranged in randomized blocks, in a factorial scheme, with four replications. Ninety days after the soil incubation and 120 days after planting, soil samples were collected for chemical analysis. The slag was efficient in correcting soil acidity, and nitrogen fertilization contributed to increment acidity in the soil cultivated with rice, decreasing base saturation, as well as the Ca and Mg content. The slag application improved silicon availability, however, when associate to the nitrogen fertilization, the silicon content in the soil did not change.

    Helvetica, sans-serif;">A escória de siderurgia é um silicato de cálcio e fonte de silício, que tem ação corretiva da acidez do solo semelhante à do calcário. Apesar do seu grande potencial de uso como corretivo e fertilizante, existem poucas informações sobre seus efeitos nos atributos químicos do solo. O estudo foi realizado com a cultura do arroz, objetivando-se avaliar os efeitos da aplicação da escória de siderurgia, calcário e ureia nas alterações dos atributos químicos de um Latossolo Vermelho distrófico. Os tratamentos constaram da combinação de duas fontes de materiais corretivos (calcário e esc


    Aretusa Daniela Resende Mendes


    Full Text Available

    Helvetica, sans-serif;">A calagem é uma prática indispensável para obtenção de altos rendimentos das culturas, em solos tropicais ácidos. Objetivou-se avaliar a nutrição e produção de matéria seca de milho, em solo submetido a calagem estimada por três métodos de cálculo e adubação sulfatada. O experimento foi desenvolvido em casa-de-vegetação, em tubos de PVC, com uma planta por tubo. Utilizou-se Latossolo Vermelho distrófico (LVd, sob vegetação nativa. Foi aplicado calcário dolomítico, tipo filler, nas doses de 4,2 Mg haHelvetica, sans-serif;">-1Helvetica, sans-serif;">; 6,7 Mg haHelvetica, sans-serif;">-1Helvetica, sans-serif;">; e 8,0 Mg haHelvetica, sans-serif;">-1Helvetica, sans-serif;">, calculadas pelo método do alumínio trocável, cálcio e magnésio; método da elevação da saturação por bases; e método do tampão SMP, respectivamente, além do tratamento sem aplicação de calcário, combinados com três doses de S (10 mg dm

  8. High - velocity water jet impact on concrete samples

    Mádr, V.; Uhlář, R.; Hlaváč, L. M.; Sitek, Libor; Foldyna, Josef; Hela, R.; Bodnárová, L.; Kaličinský, J.


    Roč. 2, č. 4 (2009), s. 43-48 ISSN 2067-3809 Institutional research plan: CEZ:AV0Z30860518 Keywords : water jet * concrete * depth of penetration * disintegration volume Subject RIV: JM - Building Engineering

  9. Advances in membrane protein crystallography: in situ and in meso data collection

    Weyand, Simone; Tate, Christopher G.


    Membrane protein structural biology has made tremendous advances over the last decade but there are still many challenges associated with crystallization, data collection and structure determination. Two independent groups, Axford et al. [(2015), Acta Cryst. D71, 1228–1237] and Huang et al. [(2015), Acta Cryst. D71, 1238–1256], have published methods that make a major contribution to addressing these challenges

  10. Neuroprotective Effects of Exogenous Activin A on Oxygen-Glucose Deprivation in PC12 Cells

    Zhong-Xin Xu


    Full Text Available Ischemic cerebrovascular disease is one of the most common causes of death in the World. Exogenous activin A (ActA protects neurons against toxicity and plays a central role in regulating the brain’s response to injury. In the present study, we investigated the mechanisms involved in the neuroprotective effects of ActA in a model of hypoxic-ischemic brain disease. We found that ActA could effectively increase the survival rate of PC12 cells and relieve oxygen-glucose deprivation (OGD damage. To clarify the neuroprotective mechanisms of ActA, the effects of ActA on the ActA/Smad pathway and on the up-regulation of inducible nitric oxide synthase (NOS and superoxide dismutase (SOD were investigated using OGD in PC12 cells. The results showed that ActA could increase the expression of activin receptor IIA (ActRIIA, Smad3 and Smad4 and that 50 ng/mL and 100 ng/mL of ActA could reduce NO levels and increase SOD activity by 78.9% and 79.9%, respectively. These results suggested that the neuroprotective effects of ActA in ischemia could be related to the activation of the ActA/Smad signaling pathway and to its anti-oxidant activities.

  11. Synthesis, Characterization and Antimicrobial Activities of Some ...


    of metal ions with vitamin.111: Synthesis and infrared spectra of metal complexes with pyridoxamine and pyridoxine. Inorg. Chim. Acta, 46, 191-197. Gary, J and Adeyemo, A (1981) Interaction of vitamin B1 with Zn(II), Cd (II) and Hg(II) in. Deuterated Dimethyl Sulfoxide. Inorg. Chim. Acta, 55, 93-98. Gohzalez-vergara, E ...

  12. Life history of the invasive bug Oxycarenus lavaterae (Heteroptera: Oxycarenidae) in Bulgaria

    Nedvěd, Oldřich; Chehlarov, E.; Kalushkov, P.


    Roč. 66, č. 2 (2014), s. 203-208 ISSN 0324-0770 Institutional support: RVO:60077344 Keywords : size * weight * sexual dimorphism Subject RIV: EH - Ecology, Behaviour Impact factor: 0.532, year: 2014

  13. Endogenous protection derived from activin A/Smads transduction loop stimulated via ischemic injury in PC12 cells.

    Mang, Jing; Mei, Chun-Li; Wang, Jiao-Qi; Li, Zong-Shu; Chu, Ting-Ting; He, Jin-Ting; Xu, Zhong-Xin


    Activin A (ActA), a member of transforming growth factor-beta (TGF-b) super- family, affects many cellular processes, including ischemic stroke. Though the neuroprotective effects of exogenous ActA on oxygen-glucose deprivation (OGD) injury have already been reported by us, the endogenous role of ActA remains poorly understood. To further define the role and mechanism of endogenous ActA and its signaling in response to acute ischemic damage, we used an OGD model in PC12 cells to simulate ischemic injury on neurons in vitro. Cells were pre-treated by monoclonal antibody against activin receptor type IIA (ActRII-Ab). We found that ActRII-Ab augments ischemic injury in PC12 cells. Further, the extracellular secretion of ActA as well as phosphorylation of smad3 in PC12 cells was also up-regulated by OGD, but suppressed by ActRII-Ab. Taken together, our results show that ActRII-Ab may augment ischemic injury via blocking of transmembrane signal transduction of ActA, which confirmed the existence of endogenous neuroprotective effects derived from the ActA/Smads pathway. ActRIIA plays an important role in transferring neuronal protective signals inside. It is highly possible that ActA transmembrance signaling is a part of the positive feed-back loop for extracellular ActA secretion.

  14. Endogenous Protection Derived from Activin A/Smads Transduction Loop Stimulated via Ischemic Injury in PC12 Cells

    Zhong-Xin Xu


    Full Text Available Activin A (ActA, a member of transforming growth factor-beta (TGF-b super- family, affects many cellular processes, including ischemic stroke. Though the neuroprotective effects of exogenous ActA on oxygen-glucose deprivation (OGD injury have already been reported by us, the endogenous role of ActA remains poorly understood. To further define the role and mechanism of endogenous ActA and its signaling in response to acute ischemic damage, we used an OGD model in PC12 cells to simulate ischemic injury on neurons in vitro. Cells were pre-treated by monoclonal antibody against activin receptor type IIA (ActRII-Ab. We found that ActRII-Ab augments ischemic injury in PC12 cells. Further, the extracellular secretion of ActA as well as phosphorylation of smad3 in PC12 cells was also up-regulated by OGD, but suppressed by ActRII-Ab. Taken together, our results show that ActRII-Ab may augment ischemic injury via blocking of transmembrane signal transduction of ActA, which confirmed the existence of endogenous neuroprotective effects derived from the ActA/Smads pathway. ActRIIA plays an important role in transferring neuronal protective signals inside. It is highly possible that ActA transmembrance signaling is a part of the positive feed-back loop for extracellular ActA secretion.

  15. Advances in membrane protein crystallography: in situ and in meso data collection

    Weyand, Simone, E-mail: [Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA (United Kingdom); Tate, Christopher G., E-mail: [MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Francis Crick Avenue, Cambridge CB2 0QH (United Kingdom)


    Membrane protein structural biology has made tremendous advances over the last decade but there are still many challenges associated with crystallization, data collection and structure determination. Two independent groups, Axford et al. [(2015), Acta Cryst. D71, 1228–1237] and Huang et al. [(2015), Acta Cryst. D71, 1238–1256], have published methods that make a major contribution to addressing these challenges.

  16. The Vanishing Shakespeare: A Report by the American Council of Trustees and Alumni

    Neal, Anne D.; Mitchell, Charles


    As this report goes to press, the nation's capital is in the midst of a six-moth, city-wide celebration of William Shakespeare. With this celebration as a backdrop, the American Council of Trustees and Alumni (ACTA) researched how Shakespeare fits into English curricula at 70 of the nation's leading colleges and universities. ACTA surveyed English…

  17. Leading the Charge: Governors, Higher Education and Accountability

    American Council of Trustees and Alumni, 2014


    With this new tool, ACTA [American Council of Trustees and Alumni] is working to expand its outreach to governors nationwide on behalf of higher education reform, focusing on key issues of quality, cost, and accountability. ACTA has worked with governors and education leaders from across the country, and that experience has proven that innovative…

  18. A facile synthesis of 1,2,3-triazolyl indole hybrids via SbCl3 ...

    Ponnuswamy A and Jagatheesan R 2011 Acta Cryst. E67 o2707. 27. Fun H K, Hemamalini M, Shanmugavelan P,. Ponnuswamy A and Jagatheesan R 2011 Acta Cryst. E67 o2776. 28. Sundberg R J 1996 The Chemistry of Indoles, New York: Academic Press 113. 29. (a) Saxton J E 1997 Nat. Prod. Rep. 14 559; (b) Toyota.

  19. Application of Newly Developed Rotational Sensor for Monitoring of Mining Induced Seismic Events in The Karvina region

    Kaláb, Zdeněk; Knejzlík, Jaromír; Lednická, Markéta


    Roč. 10, č. 2 (2013), s. 197-205 ISSN 1214-9705 Institutional support: RVO:68145535 Keywords : rotational ground motion * rotational sensor * seismic monitoring Subject RIV: DC - Siesmology, Volcanology, Earth Structure Impact factor: 0.667, year: 2013

  20. Compositional variation of biotite from Variscan granitoids in central Europe: a statistic evaluation

    Buda, G.; Koller, F.; Kovács, J.; Ulrych, Jaromír


    Roč. 45, č. 1 (2004), s. 21-37 ISSN 0365-8066 Institutional research plan: CEZ:AV0Z3013912 Keywords : biotite * major element composition * discriminant function analysis Subject RIV: DB - Geology ; Mineralogy

  1. Structural analysis within the Rožná and Olší uranium deposits (Strážek Moldanubicum) for the estimation of deformation and stress conditions of underground gas storage

    Ptáček, Jiří; Melichar, R.; Hájek, Antonín; Koníček, Petr; Souček, Kamil; Staš, Lubomír; Kříž, P.; Lazárek, J.


    Roč. 10, č. 2 (2013), s. 237-246 ISSN 1214-9705 Institutional support: RVO:68145535 Keywords : structural analysis * deformation * stress * underground gas storage Subject RIV: DH - Mining, incl. Coal Mining Impact factor: 0.667, year: 2013

  2. Biogenic silica in the Bay of Bengal during the southwest monsoon

    Gupta; Sarma

    stream_size 8 stream_content_type text/plain stream_name Oceanol_Acta_20_493.pdf.txt stream_source_info Oceanol_Acta_20_493.pdf.txt Content-Encoding ISO-8859-1 Content-Type text/plain; charset=ISO-8859-1 ...

  3. UNC Pembroke Laser Scanning Confocal Microscopy Facility


    an aggregation-dependent manner. Biochim Biophys Acta (Mol. Basis of Disease) 1812:1664-1674. Technology Transfer 1    Scientific progress and...receptors and presynaptic markers in an aggregation-dependent manner. Biochim Biophys Acta (Mol. Basis of Disease) 1812:1664-1674.

  4. Cytogenetic investigations in Sciurus anomalus from Turkish Thrace (Rodentia: Sciuridae)

    Arslan, A.; Zima, Jan


    Roč. 64, č. 4 (2012), s. 421-426 ISSN 0324-0770 Institutional support: RVO:68081766 Keywords : karyotype * C-banding * Ag-NOR staining * Caucasian squirrel * Turkey Subject RIV: EG - Zoology Impact factor: 0.309, year: 2012

  5. Bibliography of Soviet Laser Developments, No. 16, April - June 1974


    Radiofiz Acta physica polonica Bulletin de I’Academic Polonaise del Sciences. Serie des Sciences Terhniqurs Akademiya nauk Armyanskoy SSR. DokUdy...V. Kryukov (0). Spectral kinetics of radiation from complex organic dye solution lasers. Acta phys. et ehem. Szeged, v. 19, no

  6. Bibliography of Soviet Laser Developments


    Radiofiz IV. SOURCE ABBREVIATIONS Acta physica polonica Bulletin de l’Academie Polonaise des Sciences. Serie des Sciences of dyes in polarized solutions. Acta phys. et ehem. Szeged, v. 20, no. 1-2, 197f J5-45. (RZhKh, 19AB, 2/75

  7. Från görande till lärande och förståelse; En studie av lärares lärande inom estetik

    Maj Asplund Carlsson


    Full Text Available

    The aim of this article is to analyse teachers’ changing ways of talking about children’s aesthetic learn-Helvetica;"> 

    ing in the early years as a result of a research and development project. With a point of departure in developmen-Helvetica;"> 

    tal and variation theory, a praxis oriented project was designed with the aim of finding out whether collaborative 

    talk and meta-cognitive dialogues could contribute to children’s learning of music, dance and poetry. The partici-Helvetica;"> 

    pating teachers were offered in-service training in order to develop a new way of teaching and new ways of think-Helvetica;"> 

    ing about the curriculum and children’s learning. Interviews with the teachers were carried out at the beginning 

    and the end of the project. The teachers’ learning was expressed in changed ways of talking about aesthetics and 

    learning. From an emphasis on personality development and the teacher’s lack of expertise with the aesthetic sub-Helvetica;"> 

    jects as an obstacle, the teachers expressed a view of having become more aware of the concept of learning objects 

    in the aesthetics, of their own role as teachers in directing

  8. The Development of Early Childhood Education as an Academic Discipline in Finland

    Eeva Hujala


    Full Text Available

    Early Childhood Education (ECE as an academic discipline has gained an academic legitimacy in Fin-Helvetica;"> 

    land in 2005. In accordance with internationally established practice, Early Childhood Education as an academic 

    field and a field of research has been set to cover the period from birth to eight years of age. The focus of ECE re-Helvetica;"> 

    search is to analyse and define the development and upbringing of young children, including such themes as 

    learning and teaching and the complex connection between child development to the growth environment. In re-Helvetica;"> 

    cent years in Finland, the internal paradigmatic discussions within academic ECE have been both enlightened and 

    critical. The emergence of an academic Early Childhood Education paradigm has been apparent in the discus-Helvetica;"> 

    sions of early pedagogy, professional growth, leadership, management and quality and as a definer of pedagogy 

    to support children’s learning. The challenge of academic Early Childhood Education is to introduce into the dis-Helvetica;"> 

    cussion ontological and epistemological issues of early childhood and thereby activate teachers and other

  9. The natural infection of birds and ticks feeding on birds with Rickettsia spp. and Coxiella burnetii in Slovakia.

    Berthová, Lenka; Slobodník, Vladimír; Slobodník, Roman; Olekšák, Milan; Sekeyová, Zuzana; Svitálková, Zuzana; Kazimírová, Mária; Špitalská, Eva


    Ixodid ticks (Acari: Ixodidae) are known as primary vectors of many pathogens causing diseases in humans and animals. Ixodes ricinus is a common ectoparasite in Europe and birds are often hosts of subadult stages of the tick. From 2012 to 2013, 347 birds belonging to 43 species were caught and examined for ticks in three sites of Slovakia. Ticks and blood samples from birds were analysed individually for the presence of Rickettsia spp. and Coxiella burnetii by PCR-based methods. Only I. ricinus was found to infest birds. In total 594 specimens of bird-attached ticks were collected (451 larvae, 142 nymphs, 1 female). Altogether 37.2% (16/43) of bird species were infested by ticks and some birds carried more than one tick. The great tit, Parus major (83.8%, 31/37) was the most infested species. In total, 6.6 and 2.7% of bird-attached ticks were infected with Rickettsia spp. and C. burnetii, respectively. Rickettsia helvetica predominated (5.9%), whereas R. monacensis (0.5%) was only sporadically detected. Coxiella burnetii was detected in 0.9%, Rickettsia spp. in 8.9% and R. helvetica in 4.2% of bird blood samples. The great tit was the bird species most infested with I. ricinus, carried R. helvetica and C. burnetti positive tick larvae and nymphs and was found to be rickettsaemic in its blood. Further studies are necessary to define the role of birds in the circulation of rickettsiae and C. burnetii in natural foci.

  10. Serological and molecular evidence for spotted fever group Rickettsia and Borrelia burgdorferi sensu lato co-infections in The Netherlands.

    Koetsveld, Joris; Tijsse-Klasen, Ellen; Herremans, Tineke; Hovius, Joppe W R; Sprong, Hein


    Only a few reported cases indicate that Rickettsia helvetica and Rickettsia monacensis can cause disease in humans. Exposure to these two spotted fever group (SFG) rickettsiae occurs through bites of Ixodes ricinus, also the primary vector of Lyme borreliosis in Europe. To date, it is unclear how often exposure to these two microorganisms results in infection or disease. We show that of all the Borrelia burgdorferi s.l.-positive ticks, 25% were co-infected with rickettsiae. Predominantly R. helvetica was detected while R. monacensis was only found in approximately 2% of the ticks. In addition, exposure to tick-borne pathogens was compared by serology in healthy blood donors, erythema migrans (EM)-patients, and patients suspected of Lyme neuroborreliosis (LNB). As could be expected, seroreactivity against B. burgdorferi sensu lato was lower in blood donors (6%) compared to EM patients (34%) and suspected LNB cases (64%). Interestingly, seroreactivity against SFG Rickettsia antigens was not detected in serum samples from blood donors (0%), but 6% of the EM patients and 21% of the LNB suspects showed anti-rickettsial antibodies. Finally, the presence of B. burgdorferi s.l. and Rickettsia spp. in cerebrospinal fluid samples of a large cohort of patients suspected of LNB (n=208) was investigated by PCR. DNA of B. burgdorferi s.l., R. helvetica and R. monacensis was detected in seventeen, four and one patient, respectively. In conclusion, our data show that B. burgdorferi s.l. and SFG rickettsiae co-infection occurs in Dutch I. ricinus and that Lyme borreliosis patients, or patients suspected of Lyme borreliosis, are indeed exposed to both tick-borne pathogens. Whether SFG rickettsiae actually cause disease, and whether co-infections alter the clinical course of Lyme borreliosis, is not clear from our data, and warrants further investigation. Copyright © 2015 Elsevier GmbH. All rights reserved.

  11. Molecular evidence of Rickettsia spp. in ixodid ticks and rodents in suburban, natural and rural habitats in Slovakia.

    Minichová, Lenka; Hamšíková, Zuzana; Mahríková, Lenka; Slovák, Mirko; Kocianová, Elena; Kazimírová, Mária; Škultéty, Ľudovít; Štefanidesová, Katarína; Špitalská, Eva


    Natural foci of tick-borne spotted fever group (SFG) rickettsiae of public health concern have been found in Slovakia, but the role of rodents in their circulation is unclear. Ticks (Ixodes ricinus, Ixodes trianguliceps, Dermacentor marginatus, Dermacentor reticulatus, Haemaphysalis concinna and Haemaphysalis inermis) and tissues of rodents (Apodemus flavicollis, Apodemus sylvaticus, Myodes glareolus, Microtus arvalis, Microtus subterraneus and Micromys minutus) were examined for the presence of SFG rickettsiae and Coxiella burnetii by molecular methods. Suburban, natural and rural habitats were monitored to acquire information on the role of ticks and rodents in the agents' maintenance in various habitat types of Slovakia. The overall prevalence of rickettsial infection in questing I. ricinus and D. marginatus was 6.6% and 21.4%, respectively. Rickettsia helvetica, R. monacensis and non-identified rickettsial species were detected in I. ricinus, whereas R. slovaca and R. raoultii were identified in D. marginatus. Rickettsia spp.-infected I. ricinus occurred during the whole tick questing period. Rickettsia helvetica dominated (80.5%) followed by R. monacensis (6.5%). The species were present in all studied habitats. Rickettsia slovaca (66.7%) and R. raoultii (33.3%) were identified in D. marginatus from the rural habitat. Apodemus flavicollis was the most infested rodent species with I. ricinus, but My. glareolus carried the highest proportion of Rickettsia-positive I. ricinus larvae. Only 0.5% of rodents (A. flavicollis) and 5.2% of engorged I. ricinus removed from My. glareolus, A. flavicollis and M. arvalis were R. helvetica- and R. monacensis-positive. Coxiella burnetii was not detected in any of the tested samples. We hypothesize that rodents could play a role as carriers of infected ticks and contribute to the maintenance of rickettsial pathogens in natural foci. Long-term presence of SFG Rickettsia spp. was confirmed in questing ticks from different habitat

  12. Scaling blockchain for the energy sector

    Dahlquist, Olivia; Hagström, Louise


    p.p1 {margin: 0.0px 0.0px 0.0px 0.0px; font: 10.0px Helvetica} Blockchain is a distributed ledger technology enabling digital transactions without the need for central governance. Once transactions are added to the blockchain, they cannot be altered. One of the main challenges of blockchain implementation is how to create a scalable network meaning verifying many transactions per second. The goal of this thesis is to survey different approaches for scaling blockchain technologies. Scalability...

  13. People’s Republic of China Scientific Abstracts, Number 177


    PAO [ARCHITECTURAL JOURNAL] No 2, June 1977 1 CHIH-WU HSUEH-PAO [ACTA BOTANICA SINICA] No 4, December 1976 13 CHIH-WU TSA-CHIH [JOURNAL OF BOTANY...10424 CSO: 4009 12 ACTA BOTANICA SINICA AUTHOR: None ORG: Three-in-one Combination Experimental Group of Peking Ch’ung-wen Vegetable Station...Physiological Processes of Stored Tomatoes" SOURCE: Peking CHIH-WU HSUEH-PAO [ACTA BOTANICA SINICA] in Chinese Vol 18, No 4, Dec 76 pp 278-283 TEXT OF

  14. People’s Republic of China Scientific Abstracts, Number 201


    original source materials or information as to the availability of full translations of these articles. CONTENTS PAGE CHIH-WU HSUEH-PAO [ACTA BOTANICA ...III - CC - 70 S § T] ACTA BOTANICA 5INICA AUTHOR: TS’AI Ch’i-kuei (5591 6386 6311 ] CH’IEN Ying-ch’ien [6929 66Q1 0241J CHDU...the Isolation and Culture of Rice (Qrvza sativa L.) Protoplasts" SOURCE: Peking CHIH-WU HSUEH-PA0 [ACTA BOTANICA SINICAj in Chinese No 2, Jun 78 pp

  15. People’s Republic of China Scientific Abstracts, Number 195.


    76 15 CHIH-WU HSUEH-PAO [ACTA BOTANICA SINICA] No 1, March 1978 16 TI-CHEN CHAN-HSIEN [EARTHQUAKE FRONT] No 2, April 1978 26 K𔃺-HSUEH...steril^UMs! and Consolidate the contradiction between the hsien and 6168 CSO: 8111/1528 15 ACTA BOTANICA SINICA AUTHOR: CHANG Te-i [l72B 1795...of Cultured Tobacco Cells" SOURCE: Peking CHIH-WU H5UEH-PA0 [_ACTA BOTANICA SINICÄ] in Chinese No 1, Mar 78 pp 1-5 TEXT OF ENGLISH ABSTRACT

  16. People’s Republic of China Scientific Abstracts, Number 185


    CONTENTS PAGE HANG-K’UNG CHIH-SHIH [AERONAUTICAL KNOWLEDGE] No 10, October 1977 .... 1 CHIH-WU HSUEH-PAO [ACTA BOTANICA SINICA] No 3, September 1977 8...launch units; 3) Chairman Hua visiting an earthquake damaged region; 4) a group of female pilots of a minority race. 3012 CSO: 4009 ACTA BOTANICA ...CHIH-WU HSUEH-PAO [ACTA BOTANICA SINICä] in Chinese Vol 19 No 3, Sep 77 pp 167-171 TEXT OF ENGLISH ABSTRACT: 1. The process of microsporogenesis

  17. Bibliography of Soviet Laser Developments. Number 45, January - February 1980.


    Kielich (NS). Quantum statistical properties of photon and phonon fields in non-degenerate hyper-Raman scattering. Acta physica polonica , v. A56, no...and phonon fields in degenerate hyper-Raman scattering. Acta physica polonica , v. A56, no. 2, 1979, 275-281. (RZhF, 1/80, 1D933) 29 ••it...salicylideneaniline. Acta physica polonica , v. A55, no. 6, 1979, 891-901. (R2hF, 1/8Ü, 1D902) 530. Kulakovskiy, V.D., I.V. Kukushkin, and V.B

  18. Bibliography of Soviet Laser Developments, Number 46, March - April 1980.


    single crystal. Acta physica polonica , v. A56, no. 4, 1979, 543-546. (RZhF, 4/80, 4D846) 650. Sverchkov, Yu.Ye., and V.P. Gapontsev (118). Parameters...levels of configurations 3d and 4p. Acta physica polonica , v. A56, no. 3, 1979, 425-430. (RZhF, 3/80, 3D279) 741. Yankovskiy, A.A. (3). Atomic spectral...Hungarian progress report on MHD plasma diagnostics. Acta technica Academiae scientiarum hungaricae, v. 87, no. 3-4, 1978, 231-232. (RZhF, 3/80, 3G259) 600

  19. Bibliography of Soviet Laser Developments. Number 42, July-August 1979.


    process. Acta physica . polonica , v. A55, no. 1, 1979, 87-93. (RZhF, 8/79, 8D233) 34 212. Ozgo, Z., T. Banoevicz, and S. Kielich (NS). Three-photon...Fluorescence and laser parameters of three new anthracene derivatives. Acta physica polonica , v. A55, no. 1, 1979, 79-86. (RZhF, 8/79, 8D603) 223...dyve laser. Part 1. Acta physics polonica , v. A55, no. 1, 1979, 73-78. (lZhF, 8/79, 8D977) 37. Goryayova, Ye.M., A.A. Krashenlnnikov, and A.V. Shablya

  20. Piezoelectric and Electrostrictive Materials for Transducer Applications. Volume 2.


    Dariington, J. Appi. Phys. 43, 4951 (1972).I 17Z. Ujina and J. Handerek, Acta Physica Polonica A53, 665 (1978). 18Z. Q. Zhuang, M. J. Haun, S. J...Solution System. Part V: Theoretical Calculations." J. Appi. Phys. (submritted). 5 A. M. Glazer, S. A. Mabud, and R. Clarke, Acta Cryst. B34, 1060 (1978...Clarke, Acta Cryst.. B34, 1060 (1978). 12A. Amrin. R. E. Newham, and L. E. Cross, J. Solid State Chemissry 37, 248 (198 1). 13 M. j. Haun, E

  1. International Conference on the Physics of Electronic and Atomic Collisions (14th) Held in Palo Alto, California on 24-30 July 1985 (Electronic and Atomic Collisions. Invited Papers)


    76] A. Zastawny, Acta . Phys. Polonica , A46 (1974) 39. 77] R. GrUnberg, Z. Naturforsch., A24 (169) 1039. 78] R. Grnberg, Z. Naturforsch., A 3 (1978...Rev. A12 (1975) 1825. 24) A.K. Pradhan, Phys. Rev. Lett. 32 (1983) 84. 47 (1981) 79. 25) Jia-Ming Li(C.M. Lee), Acta Physica Sinica 32 (1983) 84. 26...1985) XXX. 33) H. Bethe, Ann. Physik 5(1930) 325. 34) M. Inokuti, Rev. Mod. Phys. 43 (1971) 279. 35) Bo-Cang Tian, Jia-Ming Li(C.M. Lee), Acta Physica

  2. Bibliography of Soviet Laser Developments, Number 37, September - October 1978


    systems. Acta physica polonica , v. A53, no. 5, 1978, 737- 746. (RZhRadiot, 10/78, 10Ye570) 31 226. Kolokolov, A,A., and A.I. Sukov (174). Beam... Acta physica polonica , v. A53, no. 2, 1978, 357-359. (RZhF, 9/78, 9D1119) 315. Kulla, P. (NS). Holographic black and white television system...KNLTA) KLDV (KLDVA) KSpF (KRSFA) MZhiG (IMZGA) Acta physica Academiae scientiarum hungaricae Bulletin de 1’Academie Polonaise des Sciences. Serie

  3. Surgical Excision Of A Craniopharynginoma By Transcallosal ...

    complaints included: polydipsia and polyuria in one case, progressive hypopsia in the second case; headache in the third case; and hormonal manifestations in the .... Intraventricular craniopharyngiomas: topographical classification and surgical approach selection based on an extensive overview. Acta Neurochir , 2004 ,.

  4. Disease: H00203 [KEGG MEDICUS

    Full Text Available 2680 ... AUTHORS ... Ogata M, Wang DH, Ogino K ... TITLE ... Mammalian acatalasemia: the perspectives of bioinformatics and genetic toxicol...ogy. ... JOURNAL ... Acta Med Okayama 62:345-61 (2008) ... PMID

  5. Genetic diversity analysis of Labeo gonius (Hamilton, 1822) in three ...



    May 8, 2013 ... tool to characterize population-level genetic variation in various fish species ... rise to protein variants called allozymes that differ slightly in electric charges. ..... Black Sea Coast. Acta zool. Bulg. ... Inc., Florida, USA. 350 pp.

  6. EAMJ March Gingival.indd


    Mar 3, 2009 ... plaque as high as 99.6% and that of dental calculus being 75-100% .... medical records diabetes mellitus, heart disease, ... Ethical considerations: The Ethical Committee ..... bleeding in smoker and non-smoker patients. Acta.

  7. [The reception of medieval Europe in the Baltic Sea region, Papers of the XIIth Visby Symposium held at Gotland University, Visby] / Juhan Kreem

    Kreem, Juhan, 1971-


    Arvustus: The reception of medieval Europe in the Baltic Sea Region : papers of the XIIth Visby Symposium, held at Gotland University, Visby / editor: Jörn Staecker. Visby : Gotland University Press, 2009. (Acta Visbyensia ; 12)

  8. [The Reception of Medieval Europa in the Baltic Sea Region. Papers of the XIIth Visby Symposium held at Gotland University, Visby] / Stefan Donecker

    Donecker, Stefan, 1977-


    Arvustus : The Reception of Medieval Europa in the Baltic Sea Region. Papers of the XIIth Visby Symposium held at Gotland University, Visby. Viby : Gotland University Press, 2009. (Acta Visbyensia. 12)

  9. Preface

    Jung, Young Mee; Baranska, Malgorzata


    This special issue of the Spectrochimica Acta A is dedicated to the retirement of Professor Yukihiro Ozaki of Kwansei Gakuin University, Japan as an internationally well recognized scientist in molecular spectroscopy studies including vibrational and electronic spectroscopy.

  10. African Journal of Neurological Sciences - 2009 Vol. 28 No 1

    Keywords : myasthenia, spondylarthropathy, autoimmune diseases, ankylosing spondylitis. RESUME. Propos ... We report the case of an association : myasthenia-spondylarthropathy which is an original observation because this .... myasthenia gravis: autoimmune diseases and their relation to thymectomy. Acta Neurol ...

  11. A study of the influence of different rootstocks on the vegetative ...



    Nov 23, 2011 ... indicate that vegetative growth with rootstock of bitter almond, which is mostly used, was less than the other tested ..... II international symposium on pistachios and almond. Acta. Hortic. ... Almond rootstock breeding for easy.

  12. Disease: H00419 [KEGG MEDICUS

    Full Text Available ... Garg A, Agarwal AK ... TITLE ... Lipodystrophies: disorders of adipose tissue biology. ... JOURNAL ... Biochim Biophys Acta 1791:507-13 (2009) DOI:10.1016/j.bbalip.2008.12.014 ...

  13. Download this PDF file


    Key words: Welding workshops, metal tolerant plants, cadmium, lead, ..... such as Cu, Fe, Zn and Cd are essential components of ..... Heavy metal interactions in soil and implications for soil microbial ... metals and plant mineral nutrients. Acta.

  14. comparison of closed femur fracture: skeletal traction and ...

    cost-effectiveness analysis study is necessary to come up with the best ... commonly utilized full economic health analysis. It has been used to ... management to avoid bias. Patients already ..... hospital/home and external fixation. Acta. Orthop.

  15. Characterization of indigenous Pyrus germplasm of Azad Jammu ...



    Nov 16, 2009 ... drops of bromophenol blue (BPB) was added to the prepared buffer solution and stored ..... ever these techniques need enough capital outlay which is not available for ... In vitro conservation of horticultural species. Acta. Hort.

  16. Genetics Home Reference: aspartylglucosaminuria

    ... Sources for This Page Aronson NN Jr. Aspartylglycosaminuria: biochemistry and molecular biology. Biochim Biophys Acta. 1999 Oct ... not be used as a substitute for professional medical care or advice. Users with questions about a ...

  17. Disease: H01384 [KEGG MEDICUS

    Full Text Available sson O, Jonasson J, Landtblom AM ... TITLE ... Sensory ataxic neuropathy with dysarthria/dysphagia and ophthalmoplegia (SANDO). Two case reports. ... JOURNAL ... Acta Myol 30:188-90 (2011) ...

  18. About the Site

    Journals. » Abia State University Medical Students' Association Journal; » Acta Structilia ... An International Journal of Language, Literature and Gender Studies ... Ethiopian Journal of Business and Economics (The); » Ethiopian Journal of ...

  19. How Do Health Care Providers Diagnose Klinefelter Syndrome?

    ... Email Print How do health care providers diagnose Klinefelter syndrome (KS)? The only way to confirm the presence ... in 166 boys, adolescents and adults with nonmosaic Klinefelter syndrome: A Copenhagen experience. Acta Paediatrica , Jun;100(6), ...

  20. Inhibitory Effects of Various Ratios of Polysaccharides/Alkaloids from ...

    and increases survival in endotoxemic mice. Acta. Pharmacol Sin ... secretion in hyperthyroid diarrheic rats. Regul Peptides ... effect of Coptis chinensis polysaccharide in high-fat diet ... polysaccharides decrease blood sugar by inhibition of α-.

  1. Tallinna Ülikooli kirjastus tegi uue raamatusarja


    Tallinna Ülikooli kirjastus hakkas välja andma uut raamatusarja "Acta Universitatis Tallinnensis. Artes", mille avaraamatuks on Katrin Kivimaa koostatud artiklikogumik "Working with Feminism: Curating and Exhibitions in Eastern Europe"

  2. Mysids (Crustacea) from the salt pans of Mumbai, India, with a description of a new species

    Biju, A.; Panampunnayil, S.U.

    on Marine Science, University of Tokyo 256–273. Quintero C, de Roa EZ. 1973. Notas bioecologicas sobre Metamysidopsis insularis Brattegard (Crusatacea-Mysidacea) en una laguna litoral de Venezuela. Acta Biologica Venezuelica 8: 245-278. Ramamoorthy K...

  3. Sistemas de transporte inteligentes en cruces fronterizos internacionales : un estudio abarcador : facilitando el comercio y mejorando la seguridad en el transporte


    El Programa de Permisosen Fronteras Internacionales (IBC por sus siglas en ingls) fue iniciado bajo la previsin del Acta de Eficiencia de Transporte Terrestre Intermodal (ISTEA por sus siglas en ingls) en 1991. El programa fue concebido origina...

  4. Eye features in three Danish patients with multisystemic smooth muscle dysfunction syndrome

    Moller, Hans Ulrik; Fledelius, Hans C; Milewicz, Dianna M


    A de novo mutation of the ACTA2 gene encoding the smooth muscle cell α-actin has been established in patients with multisystemic smooth muscle dysfunction syndrome associated with patent ductus arteriosus and mydriasis present at birth....

  5. A Journey Along some Well-Known Curves -R-ES-ONANCEI--Ma-rc-h

    Figure 1. Cycloid. GENERAL I ARTICLE world Acta eruditorum started .... Pietro encouraged his daughter in learning science and for that purpose regularly ... mastered the technique of solving difficult problems of analytical geometry and ...

  6. Genetics Home Reference: CLN10 disease

    ... Foundation CLIMB: Children Living with Inherited Metabolic Diseases March of Dimes: Neonatal Death The ... Sources for This Page Anderson GW, Goebel HH, Simonati A. Human pathology in NCL. Biochim Biophys Acta. 2013 Nov;1832( ...

  7. Estonia : [2012] / Allan Sikk

    Sikk, Allan, 1975-


    Ülevaade Eesti valitsuses 2012. aastal toimunud muutustest, sisepoliitika olulisematest arengutest (protestid ACTA vastu, Rahvakogu kokkutulek, Silvergate, opositsiooni tegevus, arutelud ESM-i ümber, venekeelsest koolist Eestis)

  8. VISIÓN GENERAL DE LA EVALUACIÓN DEL RIESGO EN SALUD INFANTIL EMPLEANDO UN ENFOQUE POR ETAPAS DE DESARROLLO (American translation is: Overview of a Life Stage Approach to Children's Health Risk Assessment)

    Discussing the challenges associated with estimating and interpreting toxicant exposures and health risks from biomonitoring data. This extended abstract was translated in Spanish and published in Acta Toxicologica Argentina.

  9. Soviet Material on Internal Wave Effects, No. 3, April 1975,


    telemekhanika Acta phyfica polonica Akademiya naiik Armyanskoy SSR. Doklady Akademiya nauk Aserbaydzhanskoy SSR. Doklady Akademiya nauk Belorusskoy SSR... Physica status solid! Pribory i sistemy upravleniya Pribery I tekhnika eksperimenta Radietskhnika Radliotakhnika i elektronika Rafarativnyy zhurnal

  10. Bibliography of Soviet Material on Internal Waves, Number 4, January-May 1975


    tclemekhamka Acta physica polonica Akadcmiya nauk Armyanskoy SSR. Doklady A>;ademiya nauk Azerbaydzhanskoy SSR, Doklady Akademiya nauk...obraztsy, tovarnyye znaki Pustepy fizyki Physics abstracts Prikladnaya mekhanika Prikladnaya matematika i mekhanika Physica status solidi

  11. Bibliography of Soviet Laser Developments. Number 15, January - March 1974


    Radiofiz IV. SOURCE ABBREVIATIONS Acta phyeica polonica Akademiya nauk SSSR. Doklady Akademiya nauk SSSR. Izvestiya. Fizika atmosfery i...izobreteniya, promyshlennyye obraztsy, tovarnyye znaki Physica statue solidi Pribory i tekhnika eksperimenta Russian Book List Radiotekhnika i

  12. Statistical analysis of thermal conductivity of nanofluid containing ...


    four temperatures for thermal conductivity of pristine. MWCNTs ... MWCNTs. In other words, the augmentation of the ... TiO2 nanofluid, means with different letters are significantly different .... Chen L and Xie H 2010 Thermochim Acta 497 67.

  13. Micropropagation of Vaccinium bracteatum Thunb.



    Feb 13, 2013 ... Key words: Vaccinium bracteatum Thunb., plant growth regulator, tissue culture, ... vide accent to the landscape during all four seasons of .... followed by the same letter are not significantly different. .... Acta Horticulturae.


    Paul's Letter to the Galatians points to the influence of his missionary ... of the apostle's name in the first four centuries. .... Acta Theologica Supplementum 19. 2014 .... The author states that they spoke the word in Perge, not implying that they.

  15. Oral Ketamine

    Oral Ketamine: A Four-years Experience in ... Key words: Oral Ketamine, Premedication and Oncology. .... form of a letter published in 19835. .... Acta. Anaesthesiol Scandinavica, 1998; 42: 750-758. 4. Murray P. Substitution of another opioid ...

  16. Gradient High Performance Liquid Chromatography Method ...

    Purpose: To develop a gradient high performance liquid chromatography (HPLC) method for the simultaneous determination of phenylephrine (PHE) and ibuprofen (IBU) in solid ..... nimesulide, phenylephrine. Hydrochloride, chlorpheniramine maleate and caffeine anhydrous in pharmaceutical dosage form. Acta Pol.

  17. Synthesis, Characterization and DNA Cleavage of Copper(II ...

    Keywords: DNA shearing, Copper(II) complex, Dithiothreitol, Attenuated total reflectance-Fourier transform .... confirm the fragmentation of DNA by the newly .... sperm. Biochem Biophys Acta 1986; 884: 124-134. 7. Cornell NW, Crivaro KE.

  18. Detection and identification of Rickettsia species in Ixodes tick populations from Estonia.

    Katargina, Olga; Geller, Julia; Ivanova, Anna; Värv, Kairi; Tefanova, Valentina; Vene, Sirkka; Lundkvist, Åke; Golovljova, Irina


    A total of 1640 ticks collected in different geographical parts of Estonia were screened for the presence of Rickettsia species DNA by real-time PCR. DNA of Rickettsia was detected in 83 out of 1640 questing ticks with an overall prevalence of 5.1%. The majority of the ticks infected by rickettsiae were Ixodes ricinus (74 of 83), while 9 of the 83 positive ticks were Ixodes persulcatus. For rickettsial species identification, a part of the citrate synthase gltA gene was sequenced. The majority of the positive samples were identified as Rickettsia helvetica (81 out of 83) and two of the samples were identified as Rickettsia monacensis and Candidatus R. tarasevichiae, respectively. Genetic characterization based on the partial gltA gene showed that the Estonian sequences within the R. helvetica, R. monacensis and Candidatus R. tarasevichiae species demonstrated 100% similarity with sequences deposited in GenBank, originating from Rickettsia species distributed over large territories from Europe to Asia. Copyright © 2015 Elsevier GmbH. All rights reserved.

  19. High Entropy Alloys: A Current Evaluation of Founding Ideas and Core Effects and Exploring Nonlinear Alloys (Postprint)


    299 (2004). 9. S. Ranganathan , Curr. Sci. 85, 1404 (2003). 10. F. Otto, Y. Yang, H. Bei, and E.P. George, Acta Mater. 61, 2628 (2013). 11. O.N...W. Yeh, and S. Ranganathan , High-Entropy Alloys (Oxford: Butterworth-Heinemann, 2014). 33. Y. Zou, S. Maiti, W. Steurer, and R. Spolenak, Acta Mater...Intermetallics 41, 96 (2013). 36. X. Yang and Y. Zhang, Mater. Chem. Phys. 132, 233 (2012). 37. S. Ranganathan , Personal communication (Bangalore: In

  20. Effect of Water Vapor Pressure on Fatigue Crack Growth in Al-Zn-Cu-Mg Alloy Over Wide-Range Stress Intensity Factor Loading


    pressure and frequency on fatigue behaviour in 7017-T651 aluminium alloy plate, Acta Mater, 45 (1997) 281-293. [30) N.J.H. Holroyd, D. Hardie, Factors... aluminium alloys , Acta Mater, 45 (1997) 3855-3870. [33) S. Lynch, Hydrogen embrittlement phenomena and mechanisms, Corros Rev, 30 (2012) 105-123. [34...role of environmental exposure in the fatigue behaviour of an aluminium alloy , Corros Sci, 39 (1997) 2117-2141. [39) R.S. Piascik, R.P. Gangloff

  1. Current Induced Seismicity in the Paskov Mine Field

    Holub, Karel; Rušajová, Jana; Holečko, J.


    Roč. 10, č. 2 (2013), s. 181-187 ISSN 1214-9705 R&D Projects: GA MŠk LM2010008 Institutional support: RVO:68145535 Keywords : Ostrava-Karviná coal mines * seismic network * induced seismicity * location plot Subject RIV: DC - Siesmology, Volcanology, Earth Structure Impact factor: 0.667, year: 2013

  2. Study of the effect of moisture content and bending rate on the fracture toughness of rocks

    Vavro, Leona; Souček, Kamil


    Roč. 10, č. 2 (2013), s. 247-253 ISSN 1214-9705 R&D Projects: GA MŠk ED2.1.00/03.0082 Institutional support: RVO:68145535 Keywords : fracture toughness * bending rate * tensile strength Subject RIV: DB - Geology ; Mineralogy Impact factor: 0.667, year: 2013

  3. Nobel prize awards in radiochemistry

    Adloff, J.P.


    In 1996 the Editors of Radiochimica Acta brought out a special volume of the journal to celebrate the hundredth anniversary of the discovery of radioactivity. On the occasion of the 50 th anniversary of Radiochimica Acta, which follows closely upon the centenary of Marie Curie's second Nobel Prize in 1911, the author has the privilege to informally review 'Radiochemistry and Nobel Prize Awards', including discoveries of radioelements and new fields in chemistry based on radiochemical methods. (orig.)

  4. Suitability of gramineous plants as food for the phytophagous ladybird Cynegetis impunctata L. (Coleoptera: Coccinellidae)

    Kalushkov, P.; Chehlarov, E.; Nedvěd, Oldřich


    Roč. 65, č. 4 (2013), s. 561-564 ISSN 0324-0770 Grant - others:GA JU(CZ) 144/2010/100 Institutional support: RVO:60077344 Keywords : grass * development time * body mass Subject RIV: GF - Plant Pathology, Vermin, Weed, Plant Protection Impact factor: 0.357, year: 2013

  5. China Report, Economic Affairs, Energy: Status and Development -- XXVI


    better technology for open-cut mining; — renovating 9 railway trunk lines while building 8 new ones, bringing the total number in the area up to 20 and...CSO: 4013/119 91 SUPPLEMENTAL SOURCES CHINA’S SOLAR ENERGY RESOURCE DISTRIBUTION ANALYZED Beijing TAIYANGNENG XUEBAO [ACTA ENERGIAE SOLARIS...Calculation in Our Country, TAIYANGNENG XUEBAO [ACTA ENERGIAE SOLARIS SINICA], Vol 1, 1980 pp 1-9. 12553 CSO: 4013/19 102 CONSERVATION CONSERVATION

  6. The ichthyofauna of the shoreline zone in the longitudinal profile of the Danube River, Bulgaria

    Polačik, Matej; Trichkova, T.; Janáč, Michal; Vassilev, M.; Jurajda, Pavel


    Roč. 60, č. 1 (2008), s. 77-88 ISSN 0324-0770 R&D Projects: GA MŠk LC522 Grant - others:National Science Fund(BG) B-1510/05 Institutional research plan: CEZ:AV0Z60930519 Keywords : Lower Danube * shoreline zone * fish community * distribution * abundance * endangered species Subject RIV: EH - Ecology, Behaviour

  7. Chest wall reconstruction with acellular dermal matrix (Strattice™) and a TRAM flap

    Brunbjerg, Mette Eline; Juhl, Alexander Andersen; Damsgaard, Tine Engberg


    Mette Eline Brunbjerg, Alexander Andersen Juhl, Tine E. Damsgaard. "Chest wall reconstruction with acellular dermal matrix (Strattice™) and a TRAM flap.” Acta Oncol. 2013 Jun;52(5):1052-4. Epub 2012 Oct 24. PMID: 23095144......Mette Eline Brunbjerg, Alexander Andersen Juhl, Tine E. Damsgaard. "Chest wall reconstruction with acellular dermal matrix (Strattice™) and a TRAM flap.” Acta Oncol. 2013 Jun;52(5):1052-4. Epub 2012 Oct 24. PMID: 23095144...

  8. Translational Research for Muscular Dystrophy


    offspring will have exons 2-4 deleted in cre-expressing tissues. 7. JAX stock 18284: 129-Acta1tm1Hrd/J The Acta1(H40Y) knock -in allele has the...Alterations in Osteopontin Modify Muscle Size in Females in Both Humans and Mice. Med Sci Sports Exerc. 45:1060-8. 54. Hosur V, Cox ML, Burzenski LM, Riding

  9. Bibliography of Soviet Laser Developments, No. 17, July - September 1974


    dye lasers. Academia Scientiarum Hungaricae. Acta Physica . no. 1-4, 1974, 63-71. 55. Stepanov. B. I.. A. N. Rubinov. and V...FGLV FiKhOM FTP FTT GiK IAN Arm IAN B IAN Fiz IAN TK IAN Uz IT rvuz Fiz IV UZ Geod A( ta physica polonica Bulletin de l’Academie...Kozma (0). Calculating the generation frequency of dye lasers in a quasistationary regime. Acta phys. et chem. Szeged. v. 19. no

  10. Bibliography of Soviet Laser Developments Number 53, May-June 1981.


    ATPLB) Acta physica polonica CCF (CKCFA) Ceskoslovensky casopis pro fysiku DAN Az (DAZRA) Akademiya nauk Azerbaydzhanskoy SSR. Dokiady DAN B (DBLRA...holograms. Acta technika CSAV, no. 1, 1981, 117-133. (RZhRadiot, 6/81, 6Ye4ll) 529. Mirovitskiy, D.I. (0). Problems in microwave holographic...promyshlennost’ Otkr izobr (OIPOV) Otkrytiya, izobreteniya, promyshlennyye obraztsy, tovarnyye znaki PSS (PSSAB) Physica Status Solidi (A). Applied Research

  11. Bibliography of Soviet Laser Developments, Number 48 July-August 1980.


    80, 8Ye4) IV. SOURCE ABBREVIATIONS (CIRC Codens) APP (ATPLB) Acta physica polonica * BWAT (BWATA) Biuletyn Wojskowej akademji technicznej J...Ois (OPSPA) Optika i spektroskopiya OMP (OPMPA) Optlko-mekhanicheskax’a promysh lennost’ PSS (PSSAB) Physica Status Solidi (A). Applied Research PTE...Dinamika izluchayushchego gaza. no. 3, Moskva, 1980. Sb23 Acta Universitatis Palackianae Olomucensis. Facultas rerum naturalium. v. 61, Olomouc, 1979

  12. Prevention of retinopathy of prematurity in preterm infants through changes in clinical practice and SpO₂technology.

    Castillo, Armando; Deulofeut, Richard; Critz, Ann; Sola, Augusto


    To identify whether pulse oximetry technology is associated with decreased retinopathy of prematurity (ROP) and laser treatment. Inborn infants large group of inborn infants <1250 g, a change in clinical practice in combination with pulse oximetry with Masimo SET, but not without it, led to significant reduction in severe ROP and need for laser therapy. Pulse oximetry selection is important in managing critically ill infants. © 2010 The Author(s)/Acta Paediatrica © 2010 Foundation Acta Paediatrica.

  13. Silicone passive equilibrium samplers as ‘chemometers’ in eels and sediments of a Swedish lake

    Jahnke, Annika; Mayer, Philipp; McLachlan, Michael S.


    Passive equilibrium samplers deployed in two or more media of a system and allowed to come to equilibrium can be viewed as ‘chemometers’ that reflect the difference in chemical activities of contaminants between the media. We applied silicone-based equilibrium samplers to measure relative chemica...... diagenesis and sorption to phytoplankton. The ‘chemometer’ approach has the potential to become a powerful tool to study the thermodynamic controls on persistent organic chemicals in the environment and should be extended to other environmental compartments.......Passive equilibrium samplers deployed in two or more media of a system and allowed to come to equilibrium can be viewed as ‘chemometers’ that reflect the difference in chemical activities of contaminants between the media. We applied silicone-based equilibrium samplers to measure relative chemical...... activities of seven ‘indicator’ polychlorinated biphenyls (PCBs) and hexachlorobenzene in eels and sediments from a Swedish lake. Chemical concentrations in eels and sediments were also measured using exhaustive extraction methods. Lipid-normalized concentrations in eels were higher than organic carbon...


    Gloria Luque Agulló


    Full Text Available

    In the history of language teaching, the role of grammar has been addressed by a number of linguistic theories, pedagogies and, currently, within the Common European Framework of Reference for Languages (CEF. The way grammar is considered has a decisive influence on pedagogical practices, learning processes and many other areas involved in language teaching. This paper constitutes a revision of how grammar has evolved in the last fifty years paying special attention to its evolving role in both communicative (CLT and post-communicative approaches and in the CEF.From this revision, some controversial issues concerning the pedagogic value of teaching grammar will arise as well, such as whether grammar is worth teaching in the classroom or not and how it should be taught.Even though there exists a parallel linguistic framework between CLT and the CEF, some issues still need revision concerning the notion of grammatical competence and its role for language teaching.

    HelveticaNeueLTStd-It; font-size: xx-small;">HelveticaNeueLTStd-It; font-size: xx-small;">

    Helvetica, sans-serif; white-space: normal; orphans: 2; float: none; color: #000000; word-spacing: 0px;">Históricamente, el papel de la gramática en la enseñanza de lenguas se ha justificado y cuestionado tanto por teorías lingüísticas como, actualmente, dentro del Marco Común Europeo de Referencia. La forma de contemplar la gramática influye de modo fundamental en la metodología docente, en la elaboración de manuales de texto y en los procesos de aprendizaje, entre otros. Este artículo revisa el papel de la gramática en los últimos cincuenta años prestando especial atención al método comunicativo, los post-comunicativos y dentro del Marco Com

  15. Occurrence of Babesia spp., Rickettsia spp. and Bartonella spp. in Ixodes ricinus in Bavarian public parks, Germany

    Mahling Monia


    Full Text Available Abstract Background Only limited information is available about the occurrence of ticks and tick-borne pathogens in public parks, which are areas strongly influenced by human beings. For this reason, Ixodes ricinus were collected in public parks of different Bavarian cities in a 2-year survey (2009 and 2010 and screened for DNA of Babesia spp., Rickettsia spp. and Bartonella spp. by PCR. Species identification was performed by sequence analysis and alignment with existing sequences in GenBank. Additionally, coinfections with Anaplasma phagocytophilum were investigated. Results The following prevalences were detected: Babesia spp.: 0.4% (n = 17, including one pool of two larvae in 2009 and 0.5 to 0.7% (n = 11, including one pool of five larvae in 2010; Rickettsia spp.: 6.4 to 7.7% (n = 285, including 16 pools of 76 larvae in 2009. DNA of Bartonella spp. in I. ricinus in Bavarian public parks could not be identified. Sequence analysis revealed the following species: Babesia sp. EU1 (n = 25, B. divergens (n = 1, B. divergens/capreoli (n = 1, B. gibsoni-like (n = 1, R. helvetica (n = 272, R. monacensis IrR/Munich (n = 12 and unspecified R. monacensis (n = 1. The majority of coinfections were R. helvetica with A. phagocytophilum (n = 27, but coinfections between Babesia spp. and A. phagocytophilum, or Babesia spp. and R. helvetica were also detected. Conclusions I. ricinus ticks in urban areas of Germany harbor several tick-borne pathogens and coinfections were also observed. Public parks are of particularly great interest regarding the epidemiology of tick-borne pathogens, because of differences in both the prevalence of pathogens in ticks as well as a varying species arrangement when compared to woodland areas. The record of DNA of a Babesia gibsoni-like pathogen detected in I. ricinus suggests that I. ricinus may harbor and transmit more Babesia spp. than previously known. Because of their high recreational value for human beings, urban green

  16. Occurrence of Babesia spp., Rickettsia spp. and Bartonella spp. in Ixodes ricinus in Bavarian public parks, Germany.

    Schorn, Sabine; Pfister, Kurt; Reulen, Holger; Mahling, Monia; Silaghi, Cornelia


    Only limited information is available about the occurrence of ticks and tick-borne pathogens in public parks, which are areas strongly influenced by human beings. For this reason, Ixodes ricinus were collected in public parks of different Bavarian cities in a 2-year survey (2009 and 2010) and screened for DNA of Babesia spp., Rickettsia spp. and Bartonella spp. by PCR. Species identification was performed by sequence analysis and alignment with existing sequences in GenBank. Additionally, coinfections with Anaplasma phagocytophilum were investigated. The following prevalences were detected: Babesia spp.: 0.4% (n = 17, including one pool of two larvae) in 2009 and 0.5 to 0.7% (n = 11, including one pool of five larvae) in 2010; Rickettsia spp.: 6.4 to 7.7% (n = 285, including 16 pools of 76 larvae) in 2009. DNA of Bartonella spp. in I. ricinus in Bavarian public parks could not be identified. Sequence analysis revealed the following species: Babesia sp. EU1 (n = 25), B. divergens (n = 1), B. divergens/capreoli (n = 1), B. gibsoni-like (n = 1), R. helvetica (n = 272), R. monacensis IrR/Munich (n = 12) and unspecified R. monacensis (n = 1). The majority of coinfections were R. helvetica with A. phagocytophilum (n = 27), but coinfections between Babesia spp. and A. phagocytophilum, or Babesia spp. and R. helvetica were also detected. I. ricinus ticks in urban areas of Germany harbor several tick-borne pathogens and coinfections were also observed. Public parks are of particularly great interest regarding the epidemiology of tick-borne pathogens, because of differences in both the prevalence of pathogens in ticks as well as a varying species arrangement when compared to woodland areas. The record of DNA of a Babesia gibsoni-like pathogen detected in I. ricinus suggests that I. ricinus may harbor and transmit more Babesia spp. than previously known. Because of their high recreational value for human beings, urban green areas are likely to remain in the research focus on

  17. [Aerobic methylobacteria as the basis for a biosensor for dichloromethane detection].

    Plekhanova, Iu V; Firsova, Iu E; Doronina, N V; Trotsenko, Iu A; Reshetilov, A N


    Cells of dichloromethane (DChM) bacteria-destructors were immobilized by sorption on different types of membranes, which were fixed on the measuring surface of a pH-sensitive field transistor. The presence of DChM in the medium (0.6-8.8 mM) led to a change in the transistor's output signal, which was determined by the appearance of H+ ions in the medium due to DChM utilization by methylobateria. Among four strains of methylobacteria--Methylobacterium dichloromethanicum DM4, Methylobacterium extorquens DM 17, Methylopila helvetica DM6, and Ancylobacter dichloromethanicus DM 16--the highest and most stable activity toward DChM degradation was observed in the strain M. dichloromethanicum DM4. Among 11 types of membranes for cell immobilization, Millipore nitrocellulose membranes and chromatographic fiber paper GF/A, which allow one to obtain stable biosensor signals for 2 weeks without a bioreceptor change, were chosen as optimal carriers.

  18. [Adaptation of aerobic methylobacteria to dichloromethane degradation].

    Torgonskaia, M L; Firsova, Iu E; Doronina, N V; Trotsenko, Iu A


    A shortening of the lag phase in dichloromethane (DCM) consumption was observed in the methylobacteria Methylopila helvetica DM6 and Albibacter methylovorans DM10 after prior growth on methanol with the presence of 1.5% NaCI. Neither heat nor acid stress accelerated methylobacterium adaptation to DCM consumption. Sodium azide (1 mM) and potassium cyanide (1 mM) inhibited consumption of DCM by these degraders but not by transconjugants Methylobacterium extorquens AM1, expressing DCM dehalogenase but unable to grow on DCM. This indicates that the degrader strains possess energy-dependent systems of transport of DCM or chloride anions produced during DCM dehalogenation. Inducible proteins were found in the membrane fraction of A. methylovorans DM10 cells adapted to DCM and elevated NaCl concentration.

  19. Um Breve Panorama das Relações entre Política e Religião no Contexto do Estado Moderno

    Marco Aurélio Lagreca Casamasso


    Full Text Available Helvetica,sans-serif; font-size: 12px; text-align: justify;">O artigo objetiva proporcionar, a partir da perspectiva do pensamento político moderno, um breve panorama do modelo de relação que se estabelece entre a política e a religião no contexto do Estado Moderno. Destaca-se a hegemonia do poder estatal no âmbito da sociedade política e, em particular, sua supremacia em face da religião e dos atores religiosos. Apresenta-se um relato sucinto da problemática político-religiosa no pensamento de Maquiavel, Hobbes, Spinoza, Locke, Montesquieu e Rousseau.

  20. Dicty_cDB: Contig-U04201-1 [Dicty_cDB

    Full Text Available ( CN212621 ) 26120 Suspension culture Solanum tuberosum cDNA, ... 58 6e-04 1 ( BU880962 ) UM57TA10 Populus flower cDNA library...m cD... 58 6e-08 2 ( EX067768 ) BR052412 pollen cDNA library KBPL Brassica rapa s... 48 8e-08 3 ( EX122995 ) BR106825 mature gre...2 ( EX137140 ) BR120970 root cDNA library KHRT Brassica rapa sub... 48 1e-07 3 ( EX124319 ) BR108149 matur...5', mRNA ... 48 2e-07 2 ( BU822514 ) UB38BPG02 Populus tremula cambium cDNA library Po... 58 4e-07 2 ( EX032...U359299_1( EU359299 |pid:none) Rickettsia helvetica isolate 73-3-... 171 3e-41 EU543436_1( EU543436 |pid:none) Uncultured Ric

  1. Biostratigraphy and sequence stratigraphy of the Sarvak Formation at Fahliyan Anticline (South of Yasuj)

    Ahmadi, A.; Vaziri-Moghaddam, A.; Sayrafian, A.; Taheri, A.


    In this study, bio stratigraphy, depositional environment and sequence stratigraphy of the Sarvak Formation at Fahliyan Anticline was studied. 8 species of benthic foraminifera (4 genera) and 8 species of planktonic foraminifera (11 genera) in the study area were recognized. 6 biozones have been recognized by distribution of the foraminifera, which in stratigraphic order are: Favusella washitensis Zone, Orbitolina-Alveolinids Assemblage Zone, Rudist debris Zone, Oligostegina flood Zone, Whiteinella archaeocretacea Zone and Helvetoglobotruncana helvetica Zone. On the basis of these, the age of Albian–Turonian was considered for the Sarvak Formation. Based on petrography and analysis of microfacies features 9 different microfacies types have been recognized, which can be grouped into 3 depositional environments: lagoon, shoal and open marine. The Sarvak Formation represents sedimentation on a carbonate ramp. Sequence stratigraphy analysis led to identification of 4 third-order sequences.

  2. Chemical and biological characterisation of biofilms formed on different substrata in Tisza river (Hungary)

    Kroepfl, Krisztina; Vladar, Peter; Szabo, Katalin; Acs, Eva; Borsodi, Andrea K.; Szikora, Szilvia; Caroli, Sergio; Zaray, Gyula


    Natural biofilms were simultaneously grown on granite, polished granite, andesite, polycarbonate and Plexi-glass substrata for six weeks in the Tisza River. Biofilm production and abundance of algae were influenced by the substratum. Magnitude of the substratum effect was andesite < polished granite < Plexi-glass < granite < polycarbonate. The benthic diatom community on polycarbonate had a high population of Achnantes helvetica. Bacterial activity was similar among substrates for 95 different carbon sources. The concentrations of essential elements and heavy metal pollutants (Zn, Ni, Pb and Cu) were highest in biofilms on polished granite or granite. On basis of algological, bacteriological and chemical investigations, as well as literature data, the Plexi-glass substratum is recommended for biomonitoring of river benthic microbiota. - The Plexi-glass substrate is recommended for monitoring river benthic microbiota

  3. Chemical and biological characterisation of biofilms formed on different substrata in Tisza river (Hungary)

    Kroepfl, Krisztina [Research Group of Environmental Chemistry, Hungarian Academy of Sciences, H-1518, Budapest, P.O. Box 32 (Hungary); Vladar, Peter [Research Group of Environmental Chemistry, Hungarian Academy of Sciences, H-1518, Budapest, P.O. Box 32 (Hungary); Szabo, Katalin [Department of Microbiology, Eoetvoes University, H-1518, Budapest, P.O. Box 32 (Hungary); Acs, Eva [Danube Research Station of Hungarian Academy of Sciences, H-2131 Goed (Hungary); Borsodi, Andrea K. [Department of Microbiology, Eoetvoes University, H-1518, Budapest, P.O. Box 32 (Hungary); Szikora, Szilvia [Department of Inorganic and Analytical Chemistry, Eoetvoes University, H-1518, Budapest, P.O. Box 32 (Hungary); Caroli, Sergio [Istituto Superiore di Sanita, 00161 Roma, Viale Regina Elena, 299 (Italy); Zaray, Gyula [Research Group of Environmental Chemistry, Hungarian Academy of Sciences, H-1518, Budapest, P.O. Box 32 (Hungary) and Department of Inorganic and Analytical Chemistry, Eoetvoes University, H-1518, Budapest, P.O. Box 32 (Hungary)]. E-mail:


    Natural biofilms were simultaneously grown on granite, polished granite, andesite, polycarbonate and Plexi-glass substrata for six weeks in the Tisza River. Biofilm production and abundance of algae were influenced by the substratum. Magnitude of the substratum effect was andesite < polished granite < Plexi-glass < granite < polycarbonate. The benthic diatom community on polycarbonate had a high population of Achnantes helvetica. Bacterial activity was similar among substrates for 95 different carbon sources. The concentrations of essential elements and heavy metal pollutants (Zn, Ni, Pb and Cu) were highest in biofilms on polished granite or granite. On basis of algological, bacteriological and chemical investigations, as well as literature data, the Plexi-glass substratum is recommended for biomonitoring of river benthic microbiota. - The Plexi-glass substrate is recommended for monitoring river benthic microbiota.

  4. A prospective study evaluating the presence of Rickettsia in Danish patients with sarcoidosis

    Svendsen, Claus Bo; Milman, Nils; Nielsen, Henrik Winther


    Rickettsia helvetica has previously been proposed as an aetiological agent in sarcoidosis. The purpose of the present study was to detect possible signs of Rickettsia infection in a Danish population of patients with sarcoidosis. Twenty-six patients with newly diagnosed sarcoidosis were...... interview. Evidence of rickettsial infection was assessed by an immunofluorescence assay testing for antibodies towards Rickettsia as well as specific real-time polymerase chain reaction (PCR) on lung biopsy specimens. We performed fluorescent in situ hybridization (FISH) on the biopsies to detect....... There was no difference in the reported frequency of tick bite between patients and controls. In conclusion, we found no evidence of Rickettsia being involved in the pathogenesis of sarcoidosis in Denmark....

  5. Unidades de conservação, Legislação ambiental e a APA Petrópolis

    Julieta Laudelina de Paiva


    Full Text Available Helvetica,sans-serif; font-size: 12px; text-align: justify;">As unidades de conservação são criadas com o objetivo de manter a diversidade biológica, proteger espécies ameaçadas de extinção, preservar e restaurar ecossistemas naturais. A Área de Proteção Ambiental da Região Serrana de Petrópolis – APA PETRÓPOLIS, primeira APA federal, foi criada por apresentar rica biodiversidade além de ter seus atributos naturais relativamente bem conservados. A população residente na APA Petrópolis está submetida ao cumprimento de várias determinações legais nos três níveis administrativos.

  6. Survey on tick-borne pathogens in thoroughbred horses in the Hidaka district, Hokkaido, Japan.

    Ybañez, Adrian Patalinghug; Sato, Fumio; Nambo, Yasuo; Fukui, Takashi; Masuzawa, Toshiyuki; Ohashi, Norio; Matsumoto, Kotaro; Kishimoto, Toshio; Inokuma, Hisashi


    A total of 87 Thoroughbred horses and 10 ixodid ticks from a ranch in Hidaka district, Hokkaido were tested for tick-borne diseases. Using the indirect fluorescent antibody (IFA) method, 3.4, 92.0 and 97.7% of the horses showed antibody titers of ≥ 80 against Anaplasma phagocytophilum, Rickettsia helvetica, and Borrelia garinii, respectively. This is the first report of infection with the 3 pathogens in horses in Japan. Using PCR, DNAs from the peripheral blood of all horses were found negative with any Anaplasma, Rickettsia and Borrelia spp., while those from Haemaphysalis megaspinosa ticks were found positive for Anaplasma sp. closely related to A. phagocytophilum in Japan, and A. bovis. B. japonica was also detected in an H. flava tick for the first time.

  7. First molecular evidence of Anaplasma ovis and Rickettsia spp. in keds (Diptera: Hippoboscidae) of sheep and wild ruminants.

    Hornok, Sándor; de la Fuente, José; Biró, Nóra; Fernández de Mera, Isabel G; Meli, Marina L; Elek, Vilmos; Gönczi, Eniko; Meili, Theres; Tánczos, Balázs; Farkas, Róbert; Lutz, Hans; Hofmann-Lehmann, Regina


    To evaluate the presence of rickettsial agents in hippoboscid flies with molecular methods, 81 sheep keds (Melophagus ovinus) were collected from 23 sheep, 144 deer keds (Lipoptena cervi) were caught in the environment, and a further 463 and 59 individuals of the latter species were obtained from fresh carcasses of 29 red deer and 17 roe deer, respectively. DNA was extracted individually or in pools. Anaplasma ovis was demonstrated in all examined sheep keds, and from one pool of free-living deer keds. Rickettsia helvetica or other, unidentified rickettsiae were also present in one pool of sheep keds, and in four pools of deer keds from both red deer and roe deer. This is the first account of polymerase chain reaction positivity of hippoboscid flies for A. ovis and rickettsiae. These results raise the possibility that-apart from cattle and roe deer as already reported-sheep and red deer might also play a reservoir role in the epidemiology of rickettsioses.


    Alfredo Marzano


    Full Text Available

    Helvetica;" lang="EN-US">The literature on hepatitis B virus (HBV in immunocompromised patients is heterogeneous and refers mainly to the pre-antivirals era. Currently, a rational approach to the problem of hepatitis B in these patients provides for: a the evaluation of HBV markers and of liver condition in all subjects starting immunosuppressive therapies (baseline, b the treatment with antivirals (therapy of active carriers, c the pre-emptive use of antivirals (prophylaxis in inactive carriers, especially if they are undergoing immunosuppressive therapies judged to be at high risk, d the biochemical and HBsAg monitoring (or universal prophylaxis in case of high risk immunosuppression, as in onco-haematologic patients and bone marrow transplantation in subjects with markers of previous contact with HBV (HBsAg-negative and antiHBc-positive, in order to prevent reverse seroconversion.

    Helvetica;" lang="EN-US">Moreover in solid organ transplants it is suggested a strict adherence to the criteria of allocation based on the virological characteristics of both recipients and donors  and the universal prophylaxis or therapy with nucleos(tides analogs

  9. Spotted fever group rickettsiae in ticks of migratory birds in Romania.

    Mărcuţan, Ioan-Daniel; Kalmár, Zsuzsa; Ionică, Angela Monica; D'Amico, Gianluca; Mihalca, Andrei Daniel; Vasile, Cozma; Sándor, Attila D


    Birds are important hosts and dispersers of parasitic arthropods and vector-borne zoonotic pathogens. Particularly migratory species may carry these parasites over long distances in short time periods. Migratory hotspots present ideal conditions to get a snapshot of parasite and pathogen diversity of birds migrating between continents. The aim of this study was to investigate the presence and diversity of Rickettsia spp. in ticks collected from birds at a migratory hot-spot in the Danube Delta, Romania, eastern Europe. DNA was extracted from ticks that were collected from migratory birds in the Danube Delta during migratory seasons in 2011-2012. Two 360 bp  fragments of the 16S ribosomal RNA gene and a 381 bp  fragment Gene gltA were PCR amplified and analyzed by sequence analysis (performed at Macrogen Europe, Amsterdam, The Netherlands). Nucleotide sequences were compared to reference sequences available in the GenBank database, using Basic Local Alignment Search Tool. Four hundred ticks of four different species were found on 11 bird species. The prevalence of Rickettsia spp. infection was 14 % (56/400, CI: 11.7-29.1), with significantly more nymphs hosting rickettsial infection compared to larvae (48 vs 7; P birds migrating through eastern Europe may carry ticks infected with a high diversity of rickettsial pathogens, with four Rickettsia spp. recorded. Migratory direction was important for pathogen burden, with seasonal differences in the occurrence of individual Rickettsia species. Here we report the first individual records of different Rickettsia spp. in H. concinna (R. monacensis), I. arboricola (R. helvetica, R. massiliae) and I. redikorzevi (R. helvetica) and also the first geographical record of occurrence of R. massiliae in Romania, representing the easternmost observation on the continent.

  10. Algunos límites a los derechos de los inmigrantes: detención y expulsión en la jurisprudencia del Tribunal Europeo de Derechos Humanos.*El presente trabajo se ha efectuado en el marco del proyecto de investigación SEJ2007-63476 sobre “Garantías jurídicas

    Juan Ramón Fallada García-Valle


    Full Text Available

    En este artículo se analiza la tensión entre la universalidad de los Derechos Humanos y la determinación de su reconocimiento en base a las circunstancias del caso concreto por parte del Tribunal Europeo de Derechos Humanos en sentencias relacionadas con personas extranjeras. Esa tensión se puede expresar también como la existente entre la función garantista del Estado y el principio de soberanía estatal, entre la legitimidad de la actividad estatal derivada de la existencia de límites inderogables y la legitimidad derivada del procedimiento democrático.

    Helvetica, sans-serif; font-size: 10px; white-space: pre; ">*El presente trabajo se ha efectuado en el marco del proyecto de investigación SEJ2007-63476 sobre “Garantías jurídicas frente a laHelvetica, sans-serif; font-size: 10px; white-space: pre; ">discriminación racial y étnica: estudio de casos y medidas de protección”, financiado por el Ministerio de Educación y Ciencia

  11. Novos registros do gênero Trachelomonas Ehr. (Euglenophyceae no Parque Estadual Delta do Jacuí e no Rio Grande do Sul, Brasil New records for the genus Trachelomonas Ehr. (Euglenophyceae in Jacuí Delta State Park, Rio Grande do Sul, Brazil

    Sandra Maria Alves-da-Silva


    Full Text Available O levantamento do gênero Trachelomonas Ehr. (Euglenophyceae em 26 corpos d´água da área do Parque Estadual Delta do Jacuí, localizado a 29º 56' e 30º 03'S, 5lº l2' e 51º 25'W, resultou no registro de nove novas citações de espécies de Trachelomonas Ehr. para o Estado do Rio Grande do Sul, são elas: Trachelomonas abrupta Swir. emend. Defl. var. obesa (Playf. Defl. T. conica Playf., Trachelomonas duquei Conf. & Nudelman, Trachelomonas megalacantha Cunha var. crenulatocollis Bour. & Manguin, Trachelomonas verrucosa Stockes var. granulosa (Playf. Hub.-Pest., Trachelomonas zingeri Roll, três são ainda novos registros para o país: Trachelomonas cylindraceae f. cylindraceae (Playf. Pop., Trachelomonas helvetica Lemm. emend. Defl. e Trachelomonas splendidissima Middelhoek. São apresentadas descrições, ilustrações, comentários, distribuição geográfica e a amplitude de condições ambientais em que cada táxon foi encontrado.A study of the genus Trachelomonas Ehr. (Euglenophyceae in 26 water bodies at Jacuí Delta State Park near the state capital of Rio Grande do Sul (29º56', 30º03'S; 51º12', 51º18'W revealed nine new records of Trachelomonas species for this state, as follows: Trachelomonas abrupta Swir. emend. Defl. var. obesa (Playf. Defl., T. conica Playf., Trachelomonas duquei Conf. & Nudelman, Trachelomonas megalacantha Cunha var. crenulatocollis Bour. & Manguin, Trachelomonas verrucosa Stockes var. granulosa (Playf. Hub.-Pest., Trachelomonas zingeri Roll; three are new records for Brazil: Trachelomonas cylindraceae f. cylindraceae (Playf. Pop., Trachelomonas helvetica Lemm. emend. Defl. and Trachelomonas splendidissima Middelhoek. Descriptions, illustrations, comments, geographic distribution and the range of environmental conditions in which each taxon was found are presented.

  12. Actin Nemaline Myopathy Mouse Reproduces Disease, Suggests Other Actin Disease Phenotypes and Provides Cautionary Note on Muscle Transgene Expression

    Ravenscroft, Gianina; Jackaman, Connie; Sewry, Caroline A.; McNamara, Elyshia; Squire, Sarah E.; Potter, Allyson C.; Papadimitriou, John; Griffiths, Lisa M.; Bakker, Anthony J.; Davies, Kay E.; Laing, Nigel G.; Nowak, Kristen J.


    Mutations in the skeletal muscle α-actin gene (ACTA1) cause congenital myopathies including nemaline myopathy, actin aggregate myopathy and rod-core disease. The majority of patients with ACTA1 mutations have severe hypotonia and do not survive beyond the age of one. A transgenic mouse model was generated expressing an autosomal dominant mutant (D286G) of ACTA1 (identified in a severe nemaline myopathy patient) fused with EGFP. Nemaline bodies were observed in multiple skeletal muscles, with serial sections showing these correlated to aggregates of the mutant skeletal muscle α-actin-EGFP. Isolated extensor digitorum longus and soleus muscles were significantly weaker than wild-type (WT) muscle at 4 weeks of age, coinciding with the peak in structural lesions. These 4 week-old mice were ∼30% less active on voluntary running wheels than WT mice. The α-actin-EGFP protein clearly demonstrated that the transgene was expressed equally in all myosin heavy chain (MHC) fibre types during the early postnatal period, but subsequently became largely confined to MHCIIB fibres. Ringbinden fibres, internal nuclei and myofibrillar myopathy pathologies, not typical features in nemaline myopathy or patients with ACTA1 mutations, were frequently observed. Ringbinden were found in fast fibre predominant muscles of adult mice and were exclusively MHCIIB-positive fibres. Thus, this mouse model presents a reliable model for the investigation of the pathobiology of nemaline body formation and muscle weakness and for evaluation of potential therapeutic interventions. The occurrence of core-like regions, internal nuclei and ringbinden will allow analysis of the mechanisms underlying these lesions. The occurrence of ringbinden and features of myofibrillar myopathy in this mouse model of ACTA1 disease suggests that patients with these pathologies and no genetic explanation should be screened for ACTA1 mutations. PMID:22174871

  13. Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia

    Berndt, S.I.; Skibola, C.F.; Joseph, V.; Camp, N.J.; Nieters, A.; Wang, Z.; Cozen, W.; Monnereau, A.; Wang, S.S.; Kelly, R.S.; Lan, Q.; Teras, L.R.; Chatterjee, N.; Chung, C.C.; Yeager, M.


    Genome-wide association studies (GWAS) have previously identified 13 loci associated with risk of chronic lymphocytic leukemia or small lymphocytic lymphoma (CLL). To identify additional CLL susceptibility loci, we conducted the largest meta-analysis for CLL thus far, including four GWAS with a total of 3,100 individuals with CLL (cases) and 7,667 controls. In the meta-analysis, we identified ten independent associated SNPs in nine new loci at 10q23.31 (ACTA2 or FAS (ACTA2/FAS), P = 1.22 × 10...

  14. Studies on bare and Mg-doped LiCoO2 as a cathode material for lithium ion batteries

    Reddy, MV


    Full Text Available at ScienceDirect Electrochimica Acta jo ur nal ho me p age: www.elsev ier .com/ locate /e lec tac ta Graphical Abstract Electrochimica Acta xxx (2013) xxx–xxx Studies on Bare and Mg-doped LiCoO2 as a cathode material for Lithium ion Batteries M.V. Reddy... for Lithium ion Batteries M.V. Reddy∗, Thor Wei Jie, Charl J. Jafta, Kenneth I. Ozoemena, Mkhulu K. Mathe, A. Sree Kumaran Nair, Soo Soon Peng, M. Sobri Idris, Geetha Balakrishna, Fabian I. Ezema, B.V.R. Chowdari • Layered compounds, Li...

  15. Imprinting, latchment and displacement: a mini review of early instinctual behaviour in newborn infants influencing breastfeeding success.

    Mobbs, Elsie J; Mobbs, George A; Mobbs, Anthony E D


    Instinctive behaviours have evolved favouring the mother-infant dyad based on fundamental processes of neurological development, including oral tactile imprinting and latchment. Latchment is the first stage of emotional development based on the successful achievement of biological imprinting. The mechanisms underpinning imprinting are identified and the evolutionary benefits discussed. It is proposed that the oral tactile imprint to the breast is a keystone for optimal latchment and breastfeeding, promoting evolutionary success. ©2015 The Authors. Acta Paediatrica published by John Wiley & Sons Ltd on behalf of Foundation Acta Paediatrica.

  16. Scientometric Analysis of the Journals of the Academy of Medical Sciences in Bosnia and Herzegovina.

    Masic, Izet; Begic, Edin; Zunic, Lejla


    Currently in Bosnia and Herzegovina there are 25 journals in the field of biomedicine, 6 of them are indexed in Medline/PubMed base (Medical Archives, Materia Socio-Medica, Acta Informatica Medica, Acta Medica Academica, Bosnian Journal of Basic Medical Sciences (BJBMS) and Medical Glasnik), and one (BJBMS) is indexed in Science Citation Index Expanded (SCIE)/Web of Science base. The aim of this study was to show the scope of work of the journals that were published by Academy of Medical Sciences of Bosnia and Herzegovina - Medical Archives, Materia Socio-Medica and Acta Informatica Medica. The research presents a meta-analysis of three journals, or their issues, during the calendar year 2015 (retrospective and descriptive character). During 2015 calendar year a total of 286 articles were published (in Medical Archives 104 (36.3%), in Materia Socio-Medica 99 (34.6%), and in Acta Informatica Medica 83 (29%)). Original articles are present in the highest number in all three journals (in Medical Archives 80.7%, in Materia Socio Medica 77.7%, and in Acta Informatica Medica 68.6%). In Medical Archives, 90.3% of the articles were related to the field of clinical medicine. In Materia Socio-Medica, the domain of clinical medicine and public health was the most represented. Preclinical areas are most frequent in Acta Informatica Medica. The period of 50-60 days for a decision on the admission of article is most common in all three journals, with trend of shortening of that period. Articles came from 19 countries, mostly from Bosnia and Herzegovina, then from Iran, Kosovo, Saudi Arabia and Greece. In Medical Archives original articles in the field of clinical medicine (usually internal and surgical disciplines) are most often present, and that is the case in last four years. The number of articles in Materia Socio-Medica and Acta Informatica Medica is growing from year to year. In Materia Socio-Medica there is a trend of growth of articles in the field of public health

  17. Monoids of moduli spaces of manifolds

    Galatius, Søren; Randal-Williams, Oscar


    We study categories of d–dimensional cobordisms from the perspective of Tillmann [Invent. Math. 130 (1997) 257–275] and Galatius, Madsen, Tillman and Weiss [Acta Math. 202 (2009) 195–239]. There is a category C¿ of closed smooth (d - 1)–manifolds and smooth d–dimensional cobordisms, equipped...... with generalised orientations specified by a map ¿: X ¿ BO(d). The main result of [Acta Math. 202 (2009) 195–239] is a determination of the homotopy type of the classifying space BC¿. The goal of the present paper is a systematic investigation of subcategories D¿C¿ with the property that BD¿ BC¿, the smaller...

  18. Constraints in using Cerium-animaly of bulk sediments as an indicator of paleo bottom water redox environment: A case study from the Central Indian Ocean Basin

    Pattan, J.N.; Pearce, N.J.G.; Mislankar, P.G.

    for paleo-oceanic redox conditions. Geochem. Cosmo- chim. Acta 5, 1361–1371. Lyle, M., Dymond, J., Heath, G.R., 1977. Copper–nickel enriched ferromanganese nodules and associated crusts from the Baur Basin, northwest Nazca plate. Earth Planet. Sci. Lett. 35.... Cosmo- chim. Acta 61, 2375–2388. Nozaki, Y., Horible, Y., Tsubota, H., 1981. The water column distribution of thorium isotopes in the western North Pacific. Earth Planet. Sci. Lett. 66, 73–90. Pattan, J.N., Banakar, V.K., 1997. Diagenetic remobilization...

  19. People’s Republic of China Scientific Abstracts No. 179


    No 2, April 1977 7 CHIH-WU HSUEH-PAO [ACTA BOTANICA SINICA] No 2, June 1977 22 I-CH’UAN HSUEH-PAO [ACTA GENETICA SINICA] No 1...2^-129 ^675] WANG Hsiang-yun [37*9 7^9 0061] ORG: Roth of Office of Microbiology Teaching and Research, First College of Military...2799 2973 3163], SHIH Wei-k’ang [2457 3262 1660], et al. AtmiOR: None ORG: Third Teaching and Research Group, Department of Hygiene

  20. ¿DidácTICa se escribe con TIC? reflexiones sobre las TIC en el aula de ELE

    Yagüe Barredo, Agustín


    Full Text Available El presente texto, revisado y actualizado, fue presentado como desarrollo de la conferencia inaugural del IV Congreso Internacional del Español: Innovación, tecnología y comunicación en español (Salamanca, julio de 2016 para ser publicado en las Actas de dicho encuentro. Transcurrido casi un año sin que tales actas hayan sido publicadas, se comparten aquí aquellos contenidos, que reflexionan, de forma muy genérica, sobre el papel de las nuevas tecnologías en el aula de español lengua extranjera.

  1. Nobel prize awards in radiochemistry

    Adloff, J.P. [Strasbourg Univ. (France)


    In 1996 the Editors of Radiochimica Acta brought out a special volume of the journal to celebrate the hundredth anniversary of the discovery of radioactivity. On the occasion of the 50{sup th} anniversary of Radiochimica Acta, which follows closely upon the centenary of Marie Curie's second Nobel Prize in 1911, the author has the privilege to informally review 'Radiochemistry and Nobel Prize Awards', including discoveries of radioelements and new fields in chemistry based on radiochemical methods. (orig.)

  2. Determination of oxygen in uranium compounds using sulfur monochloride; Dosage de l'oxygene dans les composes de l'uranium par la methode au monochlorure de soufre

    Baudin, G; Besson, J; Blum, P L; Tran-Van, Danh [Commisariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires


    The authors have described in an other paper (Anal. Chim. Acta, in press) a method for oxygen determination in uranium compounds, in which the sample is attacked by sulfur monochloride. The present paper is concerned with the experimental aspects of the method: apparatus procedure. (authors) [French] Les auteurs ont decrit dans une autre publication (Anal. Chim. Acta) a paraitre, une methode de dosage de l'oxygene dans les composes de l'uranium par attaque par le monochlorure de soufre, La presente note a pour but d'en preciser les techniques experimentale: appareillage, mode operatoire. (auteurs)

  3. Effect of high temperatures on cement composite materials in concrete structures

    Bodnárová, L.; Válek, J.; Sitek, Libor; Foldyna, Josef


    Roč. 10, č. 2 (2013), s. 173-180 ISSN 1214-9705 R&D Projects: GA MŠk ED2.1.00/03.0082; GA ČR GAP104/12/1988 Institutional support: RVO:68145535 Keywords : high temperature * load resistance * concrete * reinforcing of mine works * fiber reinforcement Subject RIV: JJ - Other Materials Impact factor: 0.667, year: 2013

  4. Accelerated Exploration of Multi-principal Element Alloys for Structural Applications (Postprint)


    S. Ranganathan, High Entropy Alloys, Butterworth-Hei- nemann, London, UK, 2014. [6] B. Cantor , I.T.H. Chang, P. Knight, A.J.B. Vincent, Mater. Sci...Kristallogr.-Cryst. Mater. 230 (2015) 55–68. [14] B. Cantor , Entropy 16 (2014) 4749–4768. [15] O.N. Senkov, C. Woodward, D.B. Miracle, JOM. 66 (2014...2014) 1973–1983. [21] F. Otto, Y. Yang, H. Bei, E.P. George , Acta Mater. 61 (2013) 2628–2638. [22] K.Y. Tsai, M.H. Tsai, J.W. Yeh, Acta Mater. 61

  5. Phenotypes, genotypes, and prevalence of congenital myopathies older than 5 years in Denmark

    Witting, Nanna; Werlauff, Ulla; Duno, Morten


    .3% NEB mutations. Less than 5% had mutations in ACTA1, TPM2/3, MTM1, TTN, SEPN1, or SC4NA. A genetic cause was established in 83% with specific histology (cores/rods/centronuclear myopathy) vs 29% with unspecific histology. The detailed clinical examination found gene-dependent discrepancies...... in the pattern of muscle affection and walking ability. Although walking ability was delayed in patients with ACTA1, TPM2/3, and RYR1 mutations, it was within normal limits in patients with NEB and DNM2 mutations. CONCLUSIONS: We found that overall, genetic and histologic prevalence of congenital myopathy...

  6. Adiabatic Shear Bands in Simple and Dipolar Viscoplastic Materials


    d Engineering Mechanics. University of Missouri-Holla. Holla. MO 65401-0249. C S.A Mace -r. Germam .Maxirr. Cork. - DrucK GmbH Carl-i -0&sset7«v...iaxirn Gorki - Druck GmoH Car:- -Ossietzk^ -Str 30 11 7400 Auenöurs I _LL 1+ Xf . . M „ .,Mqon ACTA MECHANICA Acta Mechamca 86, .31—.1...points 13, 14, 15 and 17 becomes clear from the results plotted in Fig. 3d . The plots of the temperature rise at other points con- sidered are not

  7. A scientific review about sexual and reproductive rights on Colombia, 1994-2004

    Ospina Muñoz, Doris Elena; Castaño López, Rosa Amalia


    Estudio realizado entre julio/2005 y julio/2008 siguiendo la Base de Productos Nacionales de COLCIENCIAS (X-acta). Objetivo: caracterizar el conocimiento producido sobre derechos sexuales y reproductivos en Colombia durante 1994-2004. Metodología: se consulta X-acta utilizando descriptores. Los artículos son organizados en tres grupos según la revista en que se publican: nacionales indexadas (T1), nacionales no indexadas (T2), extranjeras (T3). Se construyen categorías. Resultados...

  8. Producción científica sobre derechos sexuales y reproductivos, Colombia 1994-2004 A scientific review about sexual and reproductive rights on Colombia, 1994-2004

    Doris Elena Ospina Muñoz; Rosa Amalia Castaño López


    Estudio realizado entre julio/2005 y julio/2008 siguiendo la Base de Productos Nacionales de COLCIENCIAS (X-acta). Objetivo: caracterizar el conocimiento producido sobre derechos sexuales y reproductivos en Colombia durante 1994-2004. Metodología: se consulta X-acta utilizando descriptores. Los artículos son organizados en tres grupos según la revista en que se publican: nacionales indexadas (T1), nacionales no indexadas (T2), extranjeras (T3). Se construyen categorías. Resultados: se identif...

  9. Mechanism of rigid overlaying of carboniferous strata failure in face mining in the case of multiseams deposit

    Jiránková, E.; Staš, Lubomír; Kajzar, Vlastimil; Doležalová, Hana


    Roč. 10, č. 2 (2013), s. 189-195 ISSN 1214-9705 R&D Projects: GA MŠk ED2.1.00/03.0082; GA MV VG20102014034 Institutional support: RVO:68145535 Keywords : subsidence trough * rock mass * overlaying strata * longwall mining * tensor stress measurement Subject RIV: DH - Mining, incl. Coal Mining Impact factor: 0.667, year: 2013

  10. Algorithm for lamotrigine dose adjustment before, during, and after pregnancy

    Sabers, A


    Sabers A. Algorithm for lamotrigine dose adjustment before, during, and after pregnancy. Acta Neurol Scand: DOI: 10.1111/j.1600-0404.2011.01627.x. © 2011 John Wiley & Sons A/S. Background -  Treatment with lamotrigine (LTG) during pregnancy is associated with a pronounced risk of seizure deterior......Sabers A. Algorithm for lamotrigine dose adjustment before, during, and after pregnancy. Acta Neurol Scand: DOI: 10.1111/j.1600-0404.2011.01627.x. © 2011 John Wiley & Sons A/S. Background -  Treatment with lamotrigine (LTG) during pregnancy is associated with a pronounced risk of seizure...

  11. Uranium spectra in the ICP

    Ghazi, A.A.; Qamar, S.; Atta, M.A. (Khan (A.Q.) Research Labs., Rawalpindi (Pakistan))


    Uranium spectra have been studied by inductively coupled plasma atomic emission spectroscopy (ICP-AES). In total, 8361 uranium lines were observed in the wavelength range of 235-500 nm. This article is an electronic publication in Spectrochimica Acta Electronica (SAE), the electronic section of Spectrochimica Acta Part B (SAB). The hard copy text is accompanied by a disk with data files and test files for an IBM-compatible computer. The main article discusses the scientific aspects of the subject and explains the purpose of the data files. (Author).

  12. Microstructure Evolution and Mechanical Behavior of Ultrafine Ti-6Al-4V During Low Temperature Superplastic Deformation (Postprint)


    J. Cui, L. Ma, A cavity nucleation model during high temperature creep deformation of metals, Acta Metall. Mater. 41 (1993) 539e542. [49] A.H. Chokshi...dislocation activity, and diffusional creep [2]. However, the contribution of these elease (PA): distribution unlimited. S.V. Zherebtsov et al. / Acta...interval 2 105 s1e2 103 s1 at 550 C. The strain rate sensitivity m was evaluated using the slope of log s log _ε curves or strain-rate-change

  13. Application of a PEG precipitation method for solubility screening: A tool for developing high protein concentration formulations

    Li, Li; Kantor, Angela; Warne, Nicholas


    Previous publications demonstrated that the extrapolated solubility by polyethylene glycol (PEG) precipitation method (Middaugh et al., J Biol Chem 1979; 254:367–370; Juckes, Biochim Biophys Acta 1971; 229:535–546; Foster et al., Biochim Biophys Acta 1973; 317:505; Mahadevan and Hall, AIChE J 1990; 36:1517–1528; Stevenson and Hageman, Pharm Res 1995; 12:1671–1676) has a strong correlation to experimentally measured solubility of proteins. Here, we explored the utility of extrapolated solubili...

  14. Bibliography of Soviet Laser Developments, Number 44 November - December 1979.


    from quantum noise. Acta physica polonica , v. A44, no. 6, 1979, 945-948. (RZhF, 11/79, 1ID1396) 196. Izraylev, F.M., and D.L. Shepelyanskiy (79...thermodynamics for matter plus radiation system with quadrupole interactions. Acta physica polonica , v. A55, no. 3, 1979, 413-417. (RZhF, 11/79...PSS (PSSAB) Physica Status Solidi (A). Applied Research (PSSBB) Physica Status Solidi (B). Basic Research r£i. (PRTEA) Pribory i tekhnika eksperimenta

  15. High-Temperature Ferromagnetism in Transition Metal Implanted Wide-Bandgap Semiconductors


    Mn)As and Its Heterostructures,” Acta Physica Polonica A, 94 (2):155–164 (August 1998). 79. Ohno, Y., D. K. Young, B. Beschoten, F. Matsukura, H. Ohno...reactive molecular-beam epitaxy,” Physical Review B , 67 (16):16205 (April 2003). 26. Dietl, T. “From Magnetic Polarons to Ferromagnetism,” Acta Physica ...samples,” Physica B , 308-310 :985–988 (December 2001). 15. Bradley, F. N. Materials for Magnetic Functions (First Edition). New York: Hayden, 1971. 16

  16. Electronic Structure of Lithium Tetraborate


    and Optical Properties of Li2B4O7 Single Crystals Pure and Doped with Yb, Co and Mn Ions for Nonlinear Applications," Acta Physica Polonica A 107...34Growth and Optical Properties of Li2B4O7 Single Crystals Pure and Doped with Yb, Co and Mn Ions for Nonlinear Applications," Acta Physica ... Polonica A 107, 507 (2005). 22. Y. V. Burak, B. V. Padlyak, and V. M. Shevel, "Radiation-induced centers in the Li2B4O7 single crystals," Nuclear

  17. Bibliography of Soviet Laser Developments, Number 28, March - April 1977.


    Acta physica polonica , v. ASO, no.3, 1976, 375-382. (RZhF, 4/77, 4D1016) 141. Lugina, A.S., N.I. Insarova, and G.S. Yakovlev (0). Generation of dif...technique to measure optical second harmonic generation in powder samples by means of electronic in- tegration. Physica status solidi (a), v.37, no.1...77, 3D1001) 23 -- -- - -- - 167. Kvasil, B. (NS). Self-focusing of radiation by Raman or Brillouin scattering. Acta technica CSAV, v.21, no.5, 1976

  18. Soviet Developments in Material Science No. 1, January - June 1975


    UkrSSR DAN UzbSSR DBAN EOM FAiO FGIV FiKhOM F-KhMM FMiM FTP FTT FZh GiA GiK IAN Arm IAN Az AvtomaLika i tclemekhanika Acta physica ...creep dynamics of the quasi-elastir^liy bound yortices in type II superconductors. Acta phys . Acad. sei. hung, y. 36, no. 2, 1974, 149 - 153... polonica Akademiya nauk Armyanskoy SSR. Doklady Akademiya nauk Azerbaydzhanskoy SSR. Doklady Akademiya nauk Belorusskoy SSR. Doklady Akademiya

  19. Radio- and VUV - Excited Luminescence of YAP:Ce, YAP:Pr and YAG:Pr


    Pr 3+ ions.", Acta Physica Polonica A, 90 pp.407-10, 1996. 6. C. Pedrini, D. Bouttet, C. Dujardin, B. Moine, I. Dafinei, P. Lecoq, M. Koselja, K...34Spectroscopy and thermoluminescence of LuAIO 3:Ce" Acta Physica Polonica A,.90, pp.377-383, 1996 17. A.J. Wojtowicz, J. Glodo, W. Drozdowski, K.R. Przegietka...Malinowski, M.F. Joubert, B. Jacquier. "Simultaneous laser action at blue and orange wavelengths in YAG:Pr 3+ Physica Status Solidi A, 140, pp.K49-52, 1993 5

  20. A Partnership Training Program: Studying Targeted Drug Delivery Using Nanoparticles In Breast Cancer Diagnosis and Therapy


    and chemical synthesis,” Acta Physica Polonica A, vol. 113, no. 1, pp. 573–576, 2008. [34] R. Hergt, R. Hiergeist, M. Zeisberger et al., “Magnetic... Physica B, vol. 350, no. 1–3, pp. E309– E313, 2004. [18] Y. A. Gorby, T. J. Beveridge, and R. P. Blakemore, “Character- ization of the bacterial...N. Nakamura and T.Matsunaga, “Highly sensitive detection of allergen using bacterial magnetic particles,” Analytica Chimica Acta , vol. 281, no. 3, pp

  1. Uranium spectra in the ICP

    Ghazi, A.A.; Qamar, S.; Atta, M.A.


    Uranium spectra have been studied by inductively coupled plasma atomic emission spectroscopy (ICP-AES). In total, 8361 uranium lines were observed in the wavelength range of 235-500 nm. This article is an electronic publication in Spectrochimica Acta Electronica (SAE), the electronic section of Spectrochimica Acta Part B (SAB). The hard copy text is accompanied by a disk with data files and test files for an IBM-compatible computer. The main article discusses the scientific aspects of the subject and explains the purpose of the data files. (Author)

  2. The Reporting of Observational Research Studies in Dermatology Journals A Literature-Based Study

    Langan, Sinead; Schmitt, Jochen; Coenraads, Pieter-Jan; Svensson, Ake; von Elm, Erik; Williams, Hywel

    Objective: To assess the quality of reporting in observational studies in dermatology. Data Sources: Five dermatology journals-the Archives of Dermatology, the British Journal of Dermatology, the Journal of the American Academy of Dermatology, the Journal of Investigative Dermatology, and Acta

  3. Knowledge of emergency contraceptives among secondary school ...


    Dec 5, 2017 ... emergency contraceptives, while 52.5% reported that they had never heard of emergency contraceptives. ... are freely available to women of all ages in South Africa (SA).[4] ..... Contraceptive Technology. .... prescribing pattern of emergency contraceptives by health care workers in Kampala, Uganda. Acta.

  4. Towards guidelines for informed consent for prospective stem cell ...


    Aug 2, 2015 ... of genes that reactivate the embryonic genetic programme.[5,6]. We, and many ... ever more complex and multifaceted ethical issues, many of which require new guidelines, consent protocols and even change in legislation, since they do not ..... Progress and prospects in stem cells therapy. Acta. Pharmacol ...

  5. Governance for a New Era: A Blueprint for Higher Education Trustees

    Schmidt, Benno C.


    "Governance for a New Era: A Blueprint for Higher Education Governance," is the product of a summit facilitated by ACTA [American Council of Trustees and Alumni] and chaired by Benno Schmidt, City University of New York Board chairman. Signatories to the statement, a diverse group of 22 distinguished national leaders, include college…

  6. Verbal Modeling Behavior in Mother-Child Interaction

    Longhurst, Thomas M.; And Others


    Discusses an alternate method of examining the verbal interaction of mothers and their children in dyadic communication. The behavior of both mothers and children differed significantly according to the ages of the children involved. Acta Symbolica, 807 Jefferson Avenue, Memphis, Tennessee 38105. Subscription Rates: annually, $12.00 individuals,…

  7. Biosynthesis of acid phosphatase of baker's yeast . Characterization of a protoplast-bound fraction containing precursors of the exo-enzyme

    Boer, Pieter; Rijn, Herman J.M. van; Reinking, A.; Steyn-Parvé, Elizabeth P.


    1. 1.|Yest protoplasts, secreting acid phosphatase (orthophosphoric-monoester phosphohydrolase (acid optimum) EC contain a small amount of firmly bound enzyme, even after lysis (Van Rijn, H.J.M.; Boer, P. and Steyn-Parvé, E.P. (1972) Biochim. Biophys. Acta 268, 431–441). The major part

  8. International symposium on 'applications of zeolites in heterogeneous catalysis'


    The International Symposium on applications of zeolites in heterogeneous catalysis, organized by the Hungarian Chemical Society (Szeged, Hung. 9/11-14/78), included 48 papers, which were published in the Vertical Bar3Vertical BarActa Phys. Chem. (Szeged) 24.

  9. The Philosophy, Theoretical Bases, and Implementation of the AHAAH Model for Evaluation of Hazard from Exposure to Intense Sounds


    being associated with susceptibility— middle ear muscle responsiveness, sex , chemical exposure, prior exposure to noise, eye color, inner ear protective...temporal bones by use of a video measuring system. Acta Otolarngol. 1987;103:87–95. Hamernik RP, Ahroon WA, Patterson JH, Jr. Threshold recovery functions

  10. Iron(III) Chloride mediated reduction of Bis(1-isoquinolylcarbonyl ...

    32. Ostendorf M, Romagnoli R, Cabeza Pereiro I C, Roos. E C, Moolenaar M J, Speckamp W N and Hiemstra H. 1997 Tetrahedron: Asymmetry 8 1773. 33. Wocadlo S, Massa W and Folgado J 1993 Inorg. Chim. Acta. 207 199. 34. Bedford R B, Bruce D W, Frost R M, Goodby J W and. Hird M 2004 Chem. Commun. 2822. 35.

  11. Rapid detection of single nucleotide mutation in p53 gene based on ...

    mutation.27 Nevertheless, more than 50% of all human tumors contain p53 mutation; ... gene mutation detection in various fields of biology and medicine persuaded us to find ..... Yola M L, Eren T and Atar N 2014 Electrochim. Acta. 125 38. 26.

  12. Diagnostic and Predictive Values of Thirst, Angiotensin II, and Vasopressin During Trauma Resuscitation


    and plasma AVP and AT2 levels across a broader spectrum of hemorrhagic shock severity may be warranted. The authors wish to thank the medical, nursing ...301. 2. Olsson K. Central control of vasopressin release and thirst. Acta Paediatr Scand Suppl. 1983;305:36–9. Pr eh os p E m er g C ar e D ow nl oa

  13. Safety in Numbers


    Bicocca. Dipartimento di Informatica , Sistemistica e Comunicazione. Laboratorio di Test e Analisi del Software, Milano. Technical Report LTA:2004:05...Communications of the ACM, 1981. 24(9): pp. 563-573. 76. Thomas Reps, On the sequential nature of interprocedural program-analysis problems. Acta Informatica

  14. Effect of Electric-current Pulses on Grain-structure Evolution in Cryogenically Rolled Copper


    severely deformed dilute aluminium alloy . Acta Mater. 56, 1619 (2008). 4. T. Konkova, S. Mironov, A. Korznikov, and S.L. Semiatin: Microstructural response...phase transformation and variant selection by electric current pulses in a Cu-Zn alloy . J. Mater. Res. 29, 975 (2014). 13. I.Sh. Valeev and Z.G

  15. Superplasticity in Fine-Grained Ceramics


    Stabilized, Tetragonal Zirconia," Acta Metall. Mater., 39(12), (1991), pp. 3227-3236. 10. B. Kellett, P. Carry, and A. Mocellin , "Extrusion of Tet-ZrO2...F. Wakai, S. Sakaguchi, and H. Kato, J. Ceram. Soc. Jap., 94, 72 (1986). 8. B. Kellett, P. Carry, and A. Mocellin , J. Amer. Ceram. Soc., 74, 1922

  16. checkCIF/PLATON report Datablock: I

    If you wish to submit your CIF for publication in Acta Crystallographica Section C or E, you should upload your CIF via the web. If your CIF is to form part of a submission to another IUCr journal, you will be asked, either during electronic submission or by the Co-editor handling your paper, to upload your CIF via our web site.

  17. Low temperature molten salt synthesis of Y(sub2)Sn(sub2)O(sub7) anode material for lithium ion batteries

    Nithyadharseni, P


    Full Text Available Acta 182 (2015) 1060–1069 Low temperature molten salt synthesis of Y2Sn2O7 anode material for lithium ion batteries P. Nithyadharsenia,b, M.V. Reddya,c,*, Kenneth I. Ozoemenab,d, R. Geetha Balakrishnae, B.V.R. Chowdaria a Advanced Batteries...

  18. Nitrogen uptake by size-fractionated plankton in permanently well-mixed temperate coastal waters

    Wafar, M.V.M.; L'Helguen, S.; Raikar, V.; Maguernd, J.-F.; Le Corre, P.

    ’absorption de l’azote dans un syste`me brasse´ peu profound (Manche occidentale). Oceanol. Acta., 19, 529–537. Malone, T. C. (1980) Algal size. In Morris, I. (ed.), The Physiological Ecology of Phytoplankton. Blackwell, Oxford, UK, 433–463. Platt, T. and Li, W...

  19. ISSN 2073 ISSN 2073-9990 East Cent. Afr. J. surg. (Online) 9990 ...


    Page 69. 12. Aldemir M, Yagnur Y, Tacyildir I. The predictive factors for the necessity of operative treatment in adhesive small bowel obstruction cases. Acta Chir Belg 2004; 104; 76-80. 13. Fevang BTS, Fevang J, Lie SA, Soriede O, Svanes K, Viste A. Long-term prognosis after operation for adhesive small bowel obstruction.

  20. Genotyping of mannose-binding lectin (MBL2) codon 54 and ...

    Rabah M. Shawky


    Nov 17, 2013 ... ing attachment, ingestion and killing of opsonized pathogens by phagocytes [5] ..... pneumonia and culture-proven sepsis during the first month of life [26]. ..... variation in the serum concentration of mannan-binding protein. Acta Paediatr ... phase reactant in adults with community-acquired pneumococcal.