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Sample records for helfand tom ayres

  1. Sarcoma de Kaposi en una paciente de Santo Tomé y Príncipe

    Directory of Open Access Journals (Sweden)

    Melba Elers Bandera

    2013-10-01

    Full Text Available Se presenta el caso clínico de una paciente que fue asistida en el Hospital General "Dr. Ayres Menezes" de la República Democrática de Santo Tomé y Príncipe, por presentar fiebre y lesiones en la piel, a la cual se le diagnosticó sarcoma de Kaposi asociado a la infección por el virus de inmunodeficiencia humana/sida. La evolución tórpida y el estadio tan avanzado de la enfermedad, así como la resistencia a los fármacos antirretrovirales, ocasionaron la muerte de la fémina

  2. Ayres' bifurcated solar model

    International Nuclear Information System (INIS)

    Kalkofen, W.

    1985-01-01

    The assumptions of Ayres' model of the upper solar atmosphere are examined. It is found that the bistable character of his model is postulated - through the assumptions concerning the opacity sources and the effect of mechanical waves, which are allowed to destroy the CO molecules but not to heat the gas. The neglect of cooling by metal lines is based on their reduced local cooling rate, but it ignores the increased depth over which this cooling occurs. Thus, the bifurcated model of the upper solar atmosphere consists of two models, one cold at the temperature minimum, with a kinetic temperature of 2900 K, and the other hot, with a temperature of 4900 K. 8 references

  3. TOMS Absorbing Aerosol Index

    Data.gov (United States)

    Washington University St Louis — TOMS_AI_G is an aerosol related dataset derived from the Total Ozone Monitoring Satellite (TOMS) Sensor. The TOMS aerosol index arises from absorbing aerosols such...

  4. 75 FR 69470 - Tele Atlas North America, Inc., Currently Doing Business as Tom Tom Including Off-Site Workers...

    Science.gov (United States)

    2010-11-12

    ...,839B; TA-W-70,839C] Tele Atlas North America, Inc., Currently Doing Business as Tom Tom Including Off... Business as Tom Tom, Concord, MA; Tele Atlas North America, Inc. Currently Doing Business as Tom Tom, Detroit, MI; Tele Atlas North America, Inc. Currently Doing Business as Tom Tom, Redwood, CA; Amended...

  5. The Ayre's T-piece turns 80: A 21st century review.

    Science.gov (United States)

    Oswald, Lauren; Smith, Emma-Jane; Mathew, Malcolm; Goonasekera, Chulananda

    2018-06-07

    Ayre's T-piece, first introduced 80 years ago, continues to be widely used in pediatric anesthesia despite colossal advances in equipment and technology. We present a review of its history, advantages, and disadvantages, and place in modern-day clinical practice. © 2018 John Wiley & Sons Ltd.

  6. The Unseen Déjà-Vu: From Erkki Huhtamo's Topoi to Ken Jacobs' Remakes: Commentary to Edwin Carels "Revisiting Tom Tom: Performative anamnesis and autonomous vision in Ken Jacobs' appropriations of Tom Tom the Piper's Son".

    Science.gov (United States)

    Strauven, Wanda

    2018-01-01

    This commentary on Edwin Carels' essay "Revisiting Tom Tom : Performative anamnesis and autonomous vision in Ken Jacobs' appropriations of Tom Tom the Piper's Son " broadens up the media-archaeological framework in which Carels places his text. Notions such as Huhtamo's topos and Zielinski's "deep time" are brought into the discussion in order to point out the difficulty to see what there is to see and to question the position of the viewer in front of experimental films like Tom Tom the Piper's Son and its remakes.

  7. Doğu-Batı Ayrımı Ekseninde Oryantalizm ve Emperyalizm

    Directory of Open Access Journals (Sweden)

    Erkan DİKİCİ

    2014-11-01

    Full Text Available Öz Bu çalışma, Doğu ile Batı arasındaki ilişkiyi incelemek adına Edward Said tarafından 1978 yılında kaleme alınan “Oryantalizm” kitabında ifade edilen oryantalist yaklaşımdan yola çıkarak, Doğu-Batı ayrımına vurgu yapmakta ve bu ayrımın arkasında yatan çıkar ilişkilerini dile getirmeye çalışmaktadır. Söz konusu Doğu-Batı ayrımı ile birlikte oryantalizm ile emperyalizm arasındaki ilişkiye de temas edilmek istenmiştir. Bu ilişkiler zinciri içerisinde dile getirdiğimiz bu ayrım, Batılıların, Batılı olmayan toplumlar üzerindeki emperyalist düşünceleri uygulayabilmek amacıyla, Batılıların kendileri tarafından ortaya çıkartılmıştır. Bu nedenle çalışmanın temel amacı, Batılıların, ötekileştirdiği Batı-dışı toplumlar üzerindeki emellerine ulaşmada oryantalizmi biçilmiş kaftan olarak görmekte olduklarını ve oryantalizmi, emperyalizmin meşrulaştırıcısı olarak düşündüklerini ifade etmektir. Anahtar Kelimeler: Oryantalizm, Doğu-Batı Ayrımı, Emperyalizm, Ötekileştirme. Orientalism and Imperialism within the Concept of East-West Division This study emphasizes the East-West division based upon the orientalist approach stated in the book “Orientalism” written by Edward Said in 1978 to study the relation between the East and the West, and tries to depict the relationships based on self-interest underlying this division. With the aforesaid East and West division, it is also wanted to mention the relation between orientalism and Imperialism. The division that we have mentioned has been posed by the Westerners to carry out their imperialist thoughts over non-western societies. For his reason, the main aim of this study is to express that the westerners see orientalism perfectly suited to reach their goals over non-western societies that they have otherized, and they also think orientalism as the legitimization of imperialism. Keywords: Orientalism, East

  8. Social versus Intrapersonal ToM: Social ToM Is a Cognitive Strength for Low- and Middle-SES Children

    Science.gov (United States)

    Lucariello, Joan M.; Durand, Tina M.; Yarnell, Lisa

    2007-01-01

    Metarepresentational theory of mind (ToM) was studied in middle- and low-SES five- and six-year-olds. Two aspects of ToM were distinguished. Reasoning about one's own mental states (Intrapersonal ToM) was assessed in the intrapersonal ToM task condition and reasoning about others' mental states (Social ToM) was assessed in the social ToM task…

  9. Longitudinal Theory of Mind (ToM) Development From Preschool to Adolescence With and Without ToM Delay.

    Science.gov (United States)

    Peterson, Candida C; Wellman, Henry M

    2018-04-16

    Longitudinal tracking of 107 three- to-thirteen-year-olds in a cross-sequential design showed a 6-step theory of mind (ToM) sequence identified by a few past cross-sectional studies validly depicted longitudinal ToM development from early to middle childhood for typically developing (TD) children and those with ToM delays owing to deafness or autism. Substantively, all groups showed ToM progress throughout middle childhood. Atypical development was more extended and began and ended at lower levels than for TD children. Yet most children in all groups progressed over the study's mean 1.5 years. Findings help resolve theoretical debates about ToM development for children with and without delay and gain strength and weight via their applicability to three disparate groups varying in ToM timing and sequencing. © 2018 Society for Research in Child Development.

  10. Updating the Micro-Tom TILLING platform.

    Science.gov (United States)

    Okabe, Yoshihiro; Ariizumi, Tohru; Ezura, Hiroshi

    2013-03-01

    The dwarf tomato variety Micro-Tom is regarded as a model system for functional genomics studies in tomato. Various tomato genomic tools in the genetic background of Micro-Tom have been established, such as mutant collections, genome information and a metabolomic database. Recent advances in tomato genome sequencing have brought about a significant need for reverse genetics tools that are accessible to the larger community, because a great number of gene sequences have become available from public databases. To meet the requests from the tomato research community, we have developed the Micro-Tom Targeting-Induced Local Lesions IN Genomes (TILLING) platform, which is comprised of more than 5000 EMS-mutagenized lines. The platform serves as a reverse genetics tool for efficiently identifying mutant alleles in parallel with the development of Micro-Tom mutant collections. The combination of Micro-Tom mutant libraries and the TILLING approach enables researchers to accelerate the isolation of desirable mutants for unraveling gene function or breeding. To upgrade the genomic tool of Micro-Tom, the development of a new mutagenized population is underway. In this paper, the current status of the Micro-Tom TILLING platform and its future prospects are described.

  11. TOM9.2 Is a Calmodulin-Binding Protein Critical for TOM Complex Assembly but Not for Mitochondrial Protein Import in Arabidopsis thaliana.

    Science.gov (United States)

    Parvin, Nargis; Carrie, Chris; Pabst, Isabelle; Läßer, Antonia; Laha, Debabrata; Paul, Melanie V; Geigenberger, Peter; Heermann, Ralf; Jung, Kirsten; Vothknecht, Ute C; Chigri, Fatima

    2017-04-03

    The translocon on the outer membrane of mitochondria (TOM) facilitates the import of nuclear-encoded proteins. The principal machinery of mitochondrial protein transport seems conserved in eukaryotes; however, divergence in the composition and structure of TOM components has been observed between mammals, yeast, and plants. TOM9, the plant homolog of yeast Tom22, is significantly smaller due to a truncation in the cytosolic receptor domain, and its precise function is not understood. Here we provide evidence showing that TOM9.2 from Arabidopsis thaliana is involved in the formation of mature TOM complex, most likely by influencing the assembly of the pore-forming subunit TOM40. Dexamethasone-induced RNAi gene silencing of TOM9.2 results in a severe reduction in the mature TOM complex, and the assembly of newly imported TOM40 into the complex is impaired. Nevertheless, mutant plants are fully viable and no obvious downstream effects of the loss of TOM complex, i.e., on mitochondrial import capacity, were observed. Furthermore, we found that TOM9.2 can bind calmodulin (CaM) in vitro and that CaM impairs the assembly of TOM complex in the isolated wild-type mitochondria, suggesting a regulatory role of TOM9.2 and a possible integration of TOM assembly into the cellular calcium signaling network. Copyright © 2017 The Author. Published by Elsevier Inc. All rights reserved.

  12. LILBID-mass spectrometry of the mitochondrial preprotein translocase TOM

    International Nuclear Information System (INIS)

    Mager, Frauke; Lintzel, Julia; Nussberger, Stephan; Sokolova, Lucie; Brutschy, Bernhard

    2010-01-01

    In the present work we applied a novel mass spectrometry method termed laser-induced liquid bead ion desorption mass spectrometry (LILBID-MS) to the outer mitochondrial membrane protein translocon TOM to analyze its subunit composition and stoichiometry. With TOM core complex, purified at high pH, we demonstrate that a TOM core complex of Neurospora crassa is composed of at least two Tom40 and Tom22 molecules, respectively, and more than five small Tom subunits between 5.5 and 6.4 kDa. We show that the multiprotein complex has a total molecular mass higher than 170 depending on the number of Tom5, Tom6 and Tom7 molecules bound.

  13. LILBID-mass spectrometry of the mitochondrial preprotein translocase TOM

    Science.gov (United States)

    Mager, Frauke; Sokolova, Lucie; Lintzel, Julia; Brutschy, Bernhard; Nussberger, Stephan

    2010-11-01

    In the present work we applied a novel mass spectrometry method termed laser-induced liquid bead ion desorption mass spectrometry (LILBID-MS) to the outer mitochondrial membrane protein translocon TOM to analyze its subunit composition and stoichiometry. With TOM core complex, purified at high pH, we demonstrate that a TOM core complex of Neurospora crassa is composed of at least two Tom40 and Tom22 molecules, respectively, and more than five small Tom subunits between 5.5 and 6.4 kDa. We show that the multiprotein complex has a total molecular mass higher than 170 depending on the number of Tom5, Tom6 and Tom7 molecules bound.

  14. Tropospheric Ozone from the TOMS TDOT (TOMS-Direct-Ozone-in-Troposphere) Technique During SAFARI-2000

    Science.gov (United States)

    Stone, J. B.; Thompson, A. M.; Frolov, A. D.; Hudson, R. D.; Bhartia, P. K. (Technical Monitor)

    2002-01-01

    There are a number of published residual-type methods for deriving tropospheric ozone from TOMS (Total Ozone Mapping Spectrometer). The basic concept of these methods is that within a zone of constant stratospheric ozone, the tropospheric ozone column can be computed by subtracting stratospheric ozone from the TOMS Level 2 total ozone column, We used the modified-residual method for retrieving tropospheric ozone during SAFARI-2000 and found disagreements with in-situ ozone data over Africa in September 2000. Using the newly developed TDOT (TOMS-Direct-Ozone-in-Troposphere) method that uses TOMS radiances and a modified lookup table based on actual profiles during high ozone pollution periods, new maps were prepared and found to compare better to soundings over Lusaka, Zambia (15.5 S, 28 E), Nairobi and several African cities where MOZAIC aircraft operated in September 2000. The TDOT technique and comparisons are described in detail.

  15. "Tom Byers: The New Colossus"

    DEFF Research Database (Denmark)

    Dalsgaard, Inger Hunnerup

    2013-01-01

    Educational and social welcome strategies to American Society and Culture: SUSI director Tom Byers, The Statue of Liberty and Emma Lazarus' "New Colossus"......Educational and social welcome strategies to American Society and Culture: SUSI director Tom Byers, The Statue of Liberty and Emma Lazarus' "New Colossus"...

  16. Cryo-EM Structure of the TOM Core Complex from Neurospora crassa.

    Science.gov (United States)

    Bausewein, Thomas; Mills, Deryck J; Langer, Julian D; Nitschke, Beate; Nussberger, Stephan; Kühlbrandt, Werner

    2017-08-10

    The TOM complex is the main entry gate for protein precursors from the cytosol into mitochondria. We have determined the structure of the TOM core complex by cryoelectron microscopy (cryo-EM). The complex is a 148 kDa symmetrical dimer of ten membrane protein subunits that create a shallow funnel on the cytoplasmic membrane surface. In the core of the dimer, the β-barrels of the Tom40 pore form two identical preprotein conduits. Each Tom40 pore is surrounded by the transmembrane segments of the α-helical subunits Tom5, Tom6, and Tom7. Tom22, the central preprotein receptor, connects the two Tom40 pores at the dimer interface. Our structure offers detailed insights into the molecular architecture of the mitochondrial preprotein import machinery. Copyright © 2017 Elsevier Inc. All rights reserved.

  17. Compare and analyse marketing strategies using consumer focused studies. The case of TomTom vs. Garmin

    OpenAIRE

    Stefanova, Antonia

    2014-01-01

    The following dissertation paper focuses on a central research question that is to compare and appraise strategic marketing activities of a first mover navigation organisation, TomTom B.V., to its most prominent competitor Garmin Ltd, a successful follower. The intense situation in the global positioning systems market provides a great possibility of investigating the two giant organisations' internal environment, competitive environment and customers' purchase behaviour. In this regard, mark...

  18. Preliminary X-ray crystallographic studies of yeast mitochondrial protein Tom70p

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Yunkun [Department of Cell Biology, Center for Biophysical Sciences and Engineering, University of Alabama at Birmingham (United States); McCombs, Debbie; Nagy, Lisa; DeLucas, Lawrence [Center for Biophysical Sciences and Engineering, University of Alabama at Birmingham (United States); Sha, Bingdong, E-mail: bdsha@uab.edu [Department of Cell Biology, Center for Biophysical Sciences and Engineering, University of Alabama at Birmingham (United States)

    2006-03-01

    Tom70p is an important translocase of the outer membrane complex member and a major surface receptor of the protein-translocation machinery in the outer mitochondrial membrane. To investigate the mechanism by which Tom70p functions to deliver the mitochondrial protein precursors, the cytosolic fragment of yeast Tom70p (cTom70p) has been crystallized. Protein translocations across mitochondrial membranes play critical roles in mitochondrion biogenesis. Protein transport from the cell cytosol to the mitochondrial matrix is carried out by the translocase of the outer membrane (TOM) complex and the translocase of the inner membrane (TIM) complexes. Tom70p is an important TOM-complex member and a major surface receptor of the protein-translocation machinery in the outer mitochondrial membrane. To investigate the mechanism by which Tom70p functions to deliver the mitochondrial protein precursors, the cytosolic fragment of yeast Tom70p (cTom70p) was crystallized. The crystals diffract to 3.2 Å using a synchrotron X-ray source and belong to space group P2{sub 1}, with unit-cell parameters a = 44.89, b = 168.78, c = 83.41 Å, α = 90.00, β = 102.74, γ = 90.00°. There are two Tom70p molecules in one asymmetric unit, which corresponds to a solvent content of approximately 51%. Structure determination by MAD methods is under way.

  19. Meta-analysis of Theory of Mind (ToM) impairment in bipolar disorder.

    Science.gov (United States)

    Bora, E; Bartholomeusz, C; Pantelis, C

    2016-01-01

    Theory of mind (ToM) dysfunction is prominent in a number of psychiatric disorders, in particular, autism and schizophrenia, and can play a significant role in poor functioning. There is now emerging evidence suggesting that ToM abilities are also impaired in bipolar disorder (BP); however, the relationship between ToM deficits and mood state is not clear. We conducted a meta-analysis of ToM studies in BP. Thirty-four studies comparing 1214 patients with BP and 1097 healthy controls were included. BP groups included remitted (18 samples, 545 BP patients), subsyndromal (12 samples, 510 BP patients), and acute (manic and/or depressed) (10 samples, 159 BP patients) patients. ToM performance was significantly impaired in BP compared to controls. This impairment was evident across different types of ToM tasks (including affective/cognitive and verbal/visual) and was also evident in strictly euthymic patients with BP (d = 0.50). There were no significant differences between remitted and subsyndromal samples. However, ToM deficit was significantly more severe during acute episodes (d = 1.23). ToM impairment was significantly associated with neurocognitive and particularly with manic symptoms. Significant but modest sized ToM dysfunction is evident in remitted and subsyndromal BP. Acute episodes are associated with more robust ToM deficits. Exacerbation of ToM deficits may contribute to the more significant interpersonal problems observed in patients with acute or subsyndromal manic symptoms. There is a need for longitudinal studies comparing the developmental trajectory of ToM deficits across the course of the illness.

  20. Reducing the Language Content in ToM Tests: A Developmental Scale

    Science.gov (United States)

    Burnel, Morgane; Perrone-Bertolotti, Marcela; Reboul, Anne; Baciu, Monica; Durrleman, Stephanie

    2018-01-01

    The goal of the current study was to statistically evaluate the reliable scalability of a set of tasks designed to assess Theory of Mind (ToM) without language as a confounding variable. This tool might be useful to study ToM in populations where language is impaired or to study links between language and ToM. Low verbal versions of the ToM tasks…

  1. Researcher Interview: Tom Hudson

    Science.gov (United States)

    Tom Hudson, M.D., President and Scientific Director of the Ontario Institute for Cancer Research, describes the International Cancer Genome Consortium (ICGC), which brings together cancer genomic data and research from across the world.

  2. A Type System for Tom

    Directory of Open Access Journals (Sweden)

    Claude Kirchner

    2010-03-01

    Full Text Available Extending a given language with new dedicated features is a general and quite used approach to make the programming language more adapted to problems. Being closer to the application, this leads to less programming flaws and easier maintenance. But of course one would still like to perform program analysis on these kinds of extended languages, in particular type checking and inference. In this case one has to make the typing of the extended features compatible with the ones in the starting language. The Tom programming language is a typical example of such a situation as it consists of an extension of Java that adds pattern matching, more particularly associative pattern matching, and reduction strategies. This paper presents a type system with subtyping for Tom, that is compatible with Java's type system, and that performs both type checking and type inference. We propose an algorithm that checks if all patterns of a Tom program are well-typed. In addition, we propose an algorithm based on equality and subtyping constraints that infers types of variables occurring in a pattern. Both algorithms are exemplified and the proposed type system is showed to be sound and complete.

  3. Alternative function for the mitochondrial SAM complex in biogenesis of alpha-helical TOM proteins.

    Science.gov (United States)

    Stojanovski, Diana; Guiard, Bernard; Kozjak-Pavlovic, Vera; Pfanner, Nikolaus; Meisinger, Chris

    2007-12-03

    The mitochondrial outer membrane contains two preprotein translocases: the general translocase of outer membrane (TOM) and the beta-barrel-specific sorting and assembly machinery (SAM). TOM functions as the central entry gate for nuclear-encoded proteins. The channel-forming Tom40 is a beta-barrel protein, whereas all Tom receptors and small Tom proteins are membrane anchored by a transmembrane alpha-helical segment in their N- or C-terminal portion. Synthesis of Tom precursors takes place in the cytosol, and their import occurs via preexisting TOM complexes. The precursor of Tom40 is then transferred to SAM for membrane insertion and assembly. Unexpectedly, we find that the biogenesis of alpha-helical Tom proteins with a membrane anchor in the C-terminal portion is SAM dependent. Each SAM protein is necessary for efficient membrane integration of the receptor Tom22, whereas assembly of the small Tom proteins depends on Sam37. Thus, the substrate specificity of SAM is not restricted to beta-barrel proteins but also includes the majority of alpha-helical Tom proteins.

  4. Training older adults on Theory of Mind (ToM): transfer on metamemory.

    Science.gov (United States)

    Lecce, Serena; Bottiroli, Sara; Bianco, Federica; Rosi, Alessia; Cavallini, Elena

    2015-01-01

    Research on aging has shown a significant decline in ToM after 65 years of age. Despite these age-related difficulties, no study has yet investigated the possibility to improve ToM in older adults. To address this gap we tested the efficacy of a conversation-based ToM training with age-appropriate ToM tasks and its transfer effects on metamemory. We examined 72 older adults (Mage=67.61 years, SD=6.39 years) assigned to three training conditions: a ToM training, a physical-conversation training and a social-contact group. All participants took part in two 2-h testing and to two 2-h training sessions. Results showed that after the intervention, older adults in the ToM training group improved their mental states' understanding significantly more than participants in the physical-conversation training and in the social-contact groups. Crucially, the positive effect of the ToM intervention generalized to metamemory knowledge. This is the first study investigating the efficacy of a ToM training and its transfer effect on metacognition in older adults. From a theoretical point of view, it supports the relation between ToM and metamemory. Practical implications of these data are discussed. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  5. COGNITIVE LOAD THEORY Written by John SWELLER, Paul AYRES, and Slava KALYUGA,

    Directory of Open Access Journals (Sweden)

    Reviewed by Kadir KOZAN

    2013-04-01

    Full Text Available Cognitive load theory (2011 by John Sweller, Paul Ayres, and Slava Kalyuga presents the state-of-the art form of cognitive load theory (CLT including instructional guidelines produced by the theory so far. The book achieves this in a precise, detailed and well-organized manner thereby being very informative from the very beginning to the very end. For instance, even the preface provides an ample amount of information about CLT after stating the main premise of this theory: “Without knowledge of human cognitive processes, instructional design is blind.” (p. v. As stated in the book, CLT is that sort of a theory that informs instructional design from a cognitive perspective or on the basis of how human cognition works.

  6. Manualization of Occupational Therapy Using Ayres Sensory Integration® for Autism.

    Science.gov (United States)

    Hunt, Joanne; van Hooydonk, Elke; Faller, Patricia; Mailloux, Zoe; Schaaf, Roseann

    2017-07-01

    This article reports on the development of a Stage 3 manual (following pilot effectiveness study) for implementing occupational therapy using Ayres Sensory Integration® (OT/ASI) for children with autism spectrum disorders to enhance participation in daily occupations. Three stakeholder groups were surveyed to aid in translation of manual from research to practice (i.e., Stage 3 manual) and an expert consensus meeting was held to finalize recommendations. Data indicated that the manuals usability could be improved by including a section on frequently encountered problems and solutions, and by including video case examples. Also recommended were greater chapter uniformity, improved clarity of forms and charts, and inclusion of a glossary. Changes were made and subject to expert review and consensus using modified Delphi process. The Stage 3 manual has been rigorously vetted and is ready for practice and research replication.

  7. Biogenesis of the mitochondrial TOM complex: Mim1 promotes insertion and assembly of signal-anchored receptors.

    Science.gov (United States)

    Becker, Thomas; Pfannschmidt, Sylvia; Guiard, Bernard; Stojanovski, Diana; Milenkovic, Dusanka; Kutik, Stephan; Pfanner, Nikolaus; Meisinger, Chris; Wiedemann, Nils

    2008-01-04

    The translocase of the outer membrane (TOM complex) is the central entry gate for nuclear-encoded mitochondrial precursor proteins. All Tom proteins are also encoded by nuclear genes and synthesized as precursors in the cytosol. The channel-forming beta-barrel protein Tom40 is targeted to mitochondria via Tom receptors and inserted into the outer membrane by the sorting and assembly machinery (SAM complex). A further outer membrane protein, Mim1, plays a less defined role in assembly of Tom40 into the TOM complex. The three receptors Tom20, Tom22, and Tom70 are anchored in the outer membrane by a single transmembrane alpha-helix, located at the N terminus in the case of Tom20 and Tom70 (signal-anchored) or in the C-terminal portion in the case of Tom22 (tail-anchored). Insertion of the precursor of Tom22 into the outer membrane requires pre-existing Tom receptors while the import pathway of the precursors of Tom20 and Tom70 is only poorly understood. We report that Mim1 is required for efficient membrane insertion and assembly of Tom20 and Tom70, but not Tom22. We show that Mim1 associates with SAM(core) components to a large SAM complex, explaining its role in late steps of the assembly pathway of Tom40. We conclude that Mim1 is not only required for biogenesis of the beta-barrel protein Tom40 but also for membrane insertion and assembly of signal-anchored Tom receptors. Thus, Mim1 plays an important role in the efficient assembly of the mitochondrial TOM complex.

  8. Price Theory and Money Coupled: some Remarks on the Ayres-Martinás Theory

    Directory of Open Access Journals (Sweden)

    Zsolt Gilanyi

    2013-01-01

    Full Text Available The main concern of economic science is to explain the Wealth of Nations. This tradition implies on the one hand, that wealth must be evaluated i.e.: economic science must elaborate a price theory; on the other hand, money should be integrated in economic theories because prices are expressed in monetary terms. Mainstream economic theory succeeds in price determination (with some limits but fails on money integration, while non-mainstream monetary models succeed on money integration but fail on price determination. In this paper I argue that the Ayres-Martinás theoretical framework is a promising tentative to cope with this challenge of economic science.

  9. Ionizing radiation environment for the TOMS mission

    Science.gov (United States)

    Lauriente, M.; Maloy, J. O.; Vampola, A. L.

    1992-01-01

    The Total Ozone Mapping Spectrometer (TOMS) will fly on several different spacecraft, each having an orbit which is approximately polar and 800-980 km in altitude. A description is given of the computer-based tools used for characterizing the spacecraft interactions with the ionizing radiation environment in orbit and the susceptibility requirements for ionizing radiation compatibility. The peak flux from the model was used to derive the expected radiation-induced noise in the South Atlantic Anomaly for the new TOMS instruments intended to fly on Advanced Earth Observatory System and Earth Probe.

  10. Meet TOM - the world's first open chest paediatric/adult manikin.

    Science.gov (United States)

    Dix, Ann

    2016-07-20

    Aged 15, TOM is a model patient. He has suffered more than his fair share of life-threatening events and never complains. But then TOM is not your average sick teenager - he is the world's first open chest paediatric/adult manikin.

  11. 78 FR 12307 - Taylor, G. Tom; Notice of Filing

    Science.gov (United States)

    2013-02-22

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. ID-5705-001] Taylor, G. Tom; Notice of Filing Take notice that on February 14, 2013, G. Tom Taylor filed an application to hold interlocking positions pursuant to section 305(b) of the Federal Power Act, 16 U.S.C. 825d(b), Part 45 of the...

  12. AuTom: a novel automatic platform for electron tomography reconstruction

    KAUST Repository

    Han, Renmin

    2017-07-26

    We have developed a software package towards automatic electron tomography (ET): Automatic Tomography (AuTom). The presented package has the following characteristics: accurate alignment modules for marker-free datasets containing substantial biological structures; fully automatic alignment modules for datasets with fiducial markers; wide coverage of reconstruction methods including a new iterative method based on the compressed-sensing theory that suppresses the “missing wedge” effect; and multi-platform acceleration solutions that support faster iterative algebraic reconstruction. AuTom aims to achieve fully automatic alignment and reconstruction for electron tomography and has already been successful for a variety of datasets. AuTom also offers user-friendly interface and auxiliary designs for file management and workflow management, in which fiducial marker-based datasets and marker-free datasets are addressed with totally different subprocesses. With all of these features, AuTom can serve as a convenient and effective tool for processing in electron tomography.

  13. Highlights of TOMS Version 9 Total Ozone Algorithm

    Science.gov (United States)

    Bhartia, Pawan; Haffner, David

    2012-01-01

    The fundamental basis of TOMS total ozone algorithm was developed some 45 years ago by Dave and Mateer. It was designed to estimate total ozone from satellite measurements of the backscattered UV radiances at few discrete wavelengths in the Huggins ozone absorption band (310-340 nm). Over the years, as the need for higher accuracy in measuring total ozone from space has increased, several improvements to the basic algorithms have been made. They include: better correction for the effects of aerosols and clouds, an improved method to account for the variation in shape of ozone profiles with season, latitude, and total ozone, and a multi-wavelength correction for remaining profile shape errors. These improvements have made it possible to retrieve total ozone with just 3 spectral channels of moderate spectral resolution (approx. 1 nm) with accuracy comparable to state-of-the-art spectral fitting algorithms like DOAS that require high spectral resolution measurements at large number of wavelengths. One of the deficiencies of the TOMS algorithm has been that it doesn't provide an error estimate. This is a particular problem in high latitudes when the profile shape errors become significant and vary with latitude, season, total ozone, and instrument viewing geometry. The primary objective of the TOMS V9 algorithm is to account for these effects in estimating the error bars. This is done by a straightforward implementation of the Rodgers optimum estimation method using a priori ozone profiles and their error covariances matrices constructed using Aura MLS and ozonesonde data. The algorithm produces a vertical ozone profile that contains 1-2.5 pieces of information (degrees of freedom of signal) depending upon solar zenith angle (SZA). The profile is integrated to obtain the total column. We provide information that shows the altitude range in which the profile is best determined by the measurements. One can use this information in data assimilation and analysis. A side

  14. Tom Ford Construction, LLC Information Sheet

    Science.gov (United States)

    Tom Ford Construction, LLC (the Company) is located in Brentwood, Tennessee. The settlement involves renovation activities conducted at a property constructed prior to 1978, located in Nashville, Tennessee.

  15. TOMS/EP UV Reflectivity Daily and Monthly Zonal Means V008

    Data.gov (United States)

    National Aeronautics and Space Administration — This data product contains TOMS/EP UV Reflectivity Daily and Monthly Zonal Means Version 8 data in ASCII format. (The shortname for this Level-3 Earth Probe TOMS...

  16. Measuring Theory of Mind in Children. Psychometric Properties of the ToM Storybooks

    NARCIS (Netherlands)

    Blijd-Hoogewys, E. M. A.; van Geert, P. L. C.; Serra, M.; Minderaa, R. B.

    Although research on Theory-of-Mind (ToM) is often based on single task measurements, more comprehensive instruments result in a better understanding of ToM development. The ToM Storybooks is a new instrument measuring basic ToM-functioning and associated aspects. There are 34 tasks, tapping various

  17. Measuring Theory of Mind in Children. Psychometric Properties of the ToM Storybooks

    NARCIS (Netherlands)

    Blijd-Hoogewys, E. M. A.; van Geert, P. L. C.; Serra, M.; Minderaa, R. B.

    2008-01-01

    Although research on Theory-of-Mind (ToM) is often based on single task measurements, more comprehensive instruments result in a better understanding of ToM development. The ToM Storybooks is a new instrument measuring basic ToM-functioning and associated aspects. There are 34 tasks, tapping various

  18. 77 FR 39406 - Safety Zone; Tom Graves Memorial Fireworks, Port Bay, Wolcott, NY

    Science.gov (United States)

    2012-07-03

    ...-AA00 Safety Zone; Tom Graves Memorial Fireworks, Port Bay, Wolcott, NY AGENCY: Coast Guard, DHS. ACTION..., NY. This safety zone is intended to restrict vessels from a portion of Port Bay during the Tom Graves... necessary to ensure the safety of spectators and vessels during the Tom Graves Memorial Fireworks. This zone...

  19. Measuring theory of mind in children. Psychometric properties of the ToM Storybooks.

    Science.gov (United States)

    Blijd-Hoogewys, E M A; van Geert, P L C; Serra, M; Minderaa, R B

    2008-11-01

    Although research on Theory-of-Mind (ToM) is often based on single task measurements, more comprehensive instruments result in a better understanding of ToM development. The ToM Storybooks is a new instrument measuring basic ToM-functioning and associated aspects. There are 34 tasks, tapping various emotions, beliefs, desires and mental-physical distinctions. Four studies on the validity and reliability of the test are presented, in typically developing children (n = 324, 3-12 years) and children with PDD-NOS (n = 30). The ToM Storybooks have good psychometric qualities. A component analysis reveals five components corresponding with the underlying theoretical constructs. The internal consistency, test-retest reliability, inter-rater reliability, construct validity and convergent validity are good. The ToM Storybooks can be used in research as well as in clinical settings.

  20. Single molecule tracking fluorescence microscopy in mitochondria reveals highly dynamic but confined movement of Tom40

    Science.gov (United States)

    Kuzmenko, Anton; Tankov, Stoyan; English, Brian P.; Tarassov, Ivan; Tenson, Tanel; Kamenski, Piotr; Elf, Johan; Hauryliuk, Vasili

    2011-12-01

    Tom40 is an integral protein of the mitochondrial outer membrane, which as the central component of the Translocase of the Outer Membrane (TOM) complex forms a channel for protein import. We characterize the diffusion properties of individual Tom40 molecules fused to the photoconvertable fluorescent protein Dendra2 with millisecond temporal resolution. By imaging individual Tom40 molecules in intact isolated yeast mitochondria using photoactivated localization microscopy with sub-diffraction limited spatial precision, we demonstrate that Tom40 movement in the outer mitochondrial membrane is highly dynamic but confined in nature, suggesting anchoring of the TOM complex as a whole.

  1. Testicular morphometry and sperm reserves of local turkey toms fed ...

    African Journals Online (AJOL)

    The morphometry and sperm reserves of the testis, epididymis and vas deferens of three groups (n=5/ group) of sexually active adult local turkey toms fed isocaloric diet with varying levels (12 %, 16 %, 20 %) of protein were studied for sixteen weeks. The weights of the toms before treatment were between 3.5 – 4.5 kg, while ...

  2. Cognitive, affective, and conative theory of mind (ToM) in children with traumatic brain injury.

    Science.gov (United States)

    Dennis, Maureen; Simic, Nevena; Bigler, Erin D; Abildskov, Tracy; Agostino, Alba; Taylor, H Gerry; Rubin, Kenneth; Vannatta, Kathryn; Gerhardt, Cynthia A; Stancin, Terry; Yeates, Keith Owen

    2013-07-01

    We studied three forms of dyadic communication involving theory of mind (ToM) in 82 children with traumatic brain injury (TBI) and 61 children with orthopedic injury (OI): Cognitive (concerned with false belief), Affective (concerned with expressing socially deceptive facial expressions), and Conative (concerned with influencing another's thoughts or feelings). We analyzed the pattern of brain lesions in the TBI group and conducted voxel-based morphometry for all participants in five large-scale functional brain networks, and related lesion and volumetric data to ToM outcomes. Children with TBI exhibited difficulty with Cognitive, Affective, and Conative ToM. The perturbation threshold for Cognitive ToM is higher than that for Affective and Conative ToM, in that Severe TBI disturbs Cognitive ToM but even Mild-Moderate TBI disrupt Affective and Conative ToM. Childhood TBI was associated with damage to all five large-scale brain networks. Lesions in the Mirror Neuron Empathy network predicted lower Conative ToM involving ironic criticism and empathic praise. Conative ToM was significantly and positively related to the package of Default Mode, Central Executive, and Mirror Neuron Empathy networks and, more specifically, to two hubs of the Default Mode Network, the posterior cingulate/retrosplenial cortex and the hippocampal formation, including entorhinal cortex and parahippocampal cortex. Copyright © 2012 Elsevier Ltd. All rights reserved.

  3. The TOM Complex of Amoebozoans: the Cases of the Amoeba Acanthamoeba castellanii and the Slime Mold Dictyostelium discoideum.

    Science.gov (United States)

    Wojtkowska, Małgorzata; Buczek, Dorota; Stobienia, Olgierd; Karachitos, Andonis; Antoniewicz, Monika; Slocinska, Małgorzata; Makałowski, Wojciech; Kmita, Hanna

    2015-07-01

    Protein import into mitochondria requires a wide variety of proteins, forming complexes in both mitochondrial membranes. The TOM complex (translocase of the outer membrane) is responsible for decoding of targeting signals, translocation of imported proteins across or into the outer membrane, and their subsequent sorting. Thus the TOM complex is regarded as the main gate into mitochondria for imported proteins. Available data indicate that mitochondria of representative organisms from across the major phylogenetic lineages of eukaryotes differ in subunit organization of the TOM complex. The subunit organization of the TOM complex in the Amoebozoa is still elusive, so we decided to investigate its organization in the soil amoeba Acanthamoeba castellanii and the slime mold Dictyostelium discoideum. They represent two major subclades of the Amoebozoa: the Lobosa and Conosa, respectively. Our results confirm the presence of Tom70, Tom40 and Tom7 in the A. castellanii and D. discoideum TOM complex, while the presence of Tom22 and Tom20 is less supported. Interestingly, the Tom proteins display the highest similarity to Opisthokonta cognate proteins, with the exception of Tom40. Thus representatives of two major subclades of the Amoebozoa appear to be similar in organization of the TOM complex, despite differences in their lifestyle. Copyright © 2015 The Authors. Published by Elsevier GmbH.. All rights reserved.

  4. 33 CFR 80.170 - Sandy Hook, NJ to Tom's River, NJ.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Sandy Hook, NJ to Tom's River, NJ. 80.170 Section 80.170 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Atlantic Coast § 80.170 Sandy Hook, NJ to Tom's River...

  5. 33 CFR 80.501 - Tom's River, NJ to Cape May, NJ.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Tom's River, NJ to Cape May, NJ. 80.501 Section 80.501 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Fifth District § 80.501 Tom's River, NJ to Cape May, NJ...

  6. Plasticity of TOM complex assembly in skeletal muscle mitochondria in response to chronic contractile activity.

    Science.gov (United States)

    Joseph, Anna-Maria; Hood, David A

    2012-03-01

    We investigated the assembly of the TOM complex within skeletal muscle under conditions of chronic contractile activity-induced mitochondrial biogenesis. Tom40 import into mitochondria was increased by chronic contractile activity, as was its time-dependent assembly into the TOM complex. These changes coincided with contractile activity-induced augmentations in the expression of key protein import machinery components Tim17, Tim23, and Tom22, as well as the cytosolic chaperone Hsp90. These data indicate the adaptability of the TOM protein import complex and suggest a regulatory role for the assembly of this complex in exercise-induced mitochondrial biogenesis. Copyright © 2011 Elsevier B.V. and Mitochondria Research Society. All rights reserved. All rights reserved.

  7. Novel TPR-containing subunit of TOM complex functions as cytosolic receptor for Entamoeba mitosomal transport.

    Science.gov (United States)

    Makiuchi, Takashi; Mi-ichi, Fumika; Nakada-Tsukui, Kumiko; Nozaki, Tomoyoshi

    2013-01-01

    Under anaerobic environments, the mitochondria have undergone remarkable reduction and transformation into highly reduced structures, referred as mitochondrion-related organelles (MROs), which include mitosomes and hydrogenosomes. In agreement with the concept of reductive evolution, mitosomes of Entamoeba histolytica lack most of the components of the TOM (translocase of the outer mitochondrial membrane) complex, which is required for the targeting and membrane translocation of preproteins into the canonical aerobic mitochondria. Here we showed, in E. histolytica mitosomes, the presence of a 600-kDa TOM complex composed of Tom40, a conserved pore-forming subunit, and Tom60, a novel lineage-specific receptor protein. Tom60, containing multiple tetratricopeptide repeats, is localized to the mitosomal outer membrane and the cytosol, and serves as a receptor of both mitosomal matrix and membrane preproteins. Our data indicate that Entamoeba has invented a novel lineage-specific shuttle receptor of the TOM complex as a consequence of adaptation to an anaerobic environment.

  8. Shallow ground-water conditions, Tom Green County, Texas

    Science.gov (United States)

    Lee, J.N.

    1986-01-01

    Most of the water needs of Tom Green County, Texas, are supplied by ground water; however, the city of San Angelo is supplied by surface water. Groundwater withdrawals during 1980 (latest year for which data are available) in Tom Green County totaled about 15,300 acre-feet, all derived from shallow aquifers. Shallow aquifers in this report refer to the ground-water system generally less than 400 feet deep that contains water with less than a 10,000 milligrams per liter concentration of dissolved solids; aquifers comprising this system include: The Leona, Comanche Peak, Trinity, Blaine, San Angelo, Choza, Bullwagon, Vale, Standpipe, and Arroyo aquifers.

  9. Genome-wide analysis of intraspecific DNA polymorphism in 'Micro-Tom', a model cultivar of tomato (Solanum lycopersicum).

    Science.gov (United States)

    Kobayashi, Masaaki; Nagasaki, Hideki; Garcia, Virginie; Just, Daniel; Bres, Cécile; Mauxion, Jean-Philippe; Le Paslier, Marie-Christine; Brunel, Dominique; Suda, Kunihiro; Minakuchi, Yohei; Toyoda, Atsushi; Fujiyama, Asao; Toyoshima, Hiromi; Suzuki, Takayuki; Igarashi, Kaori; Rothan, Christophe; Kaminuma, Eli; Nakamura, Yasukazu; Yano, Kentaro; Aoki, Koh

    2014-02-01

    Tomato (Solanum lycopersicum) is regarded as a model plant of the Solanaceae family. The genome sequencing of the tomato cultivar 'Heinz 1706' was recently completed. To accelerate the progress of tomato genomics studies, systematic bioresources, such as mutagenized lines and full-length cDNA libraries, have been established for the cultivar 'Micro-Tom'. However, these resources cannot be utilized to their full potential without the completion of the genome sequencing of 'Micro-Tom'. We undertook the genome sequencing of 'Micro-Tom' and here report the identification of single nucleotide polymorphisms (SNPs) and insertion/deletions (indels) between 'Micro-Tom' and 'Heinz 1706'. The analysis demonstrated the presence of 1.23 million SNPs and 0.19 million indels between the two cultivars. The density of SNPs and indels was high in chromosomes 2, 5 and 11, but was low in chromosomes 6, 8 and 10. Three known mutations of 'Micro-Tom' were localized on chromosomal regions where the density of SNPs and indels was low, which was consistent with the fact that these mutations were relatively new and introgressed into 'Micro-Tom' during the breeding of this cultivar. We also report SNP analysis for two 'Micro-Tom' varieties that have been maintained independently in Japan and France, both of which have served as standard lines for 'Micro-Tom' mutant collections. Approximately 28,000 SNPs were identified between these two 'Micro-Tom' lines. These results provide high-resolution DNA polymorphic information on 'Micro-Tom' and represent a valuable contribution to the 'Micro-Tom'-based genomics resources.

  10. The pro-apoptotic BH3-only protein Bim interacts with components of the translocase of the outer mitochondrial membrane (TOM.

    Directory of Open Access Journals (Sweden)

    Daniel O Frank

    Full Text Available The pro-apoptotic Bcl-2-family protein Bim belongs to the BH3-only proteins known as initiators of apoptosis. Recent data show that Bim is constitutively inserted in the outer mitochondrial membrane via a C-terminal transmembrane anchor from where it can activate the effector of cytochrome c-release, Bax. To identify regulators of Bim-activity, we conducted a search for proteins interacting with Bim at mitochondria. We found an interaction of Bim with Tom70, Tom20 and more weakly with Tom40, all components of the Translocase of the Outer Membrane (TOM. In vitro import assays performed on tryptically digested yeast mitochondria showed reduced Bim insertion into the outer mitochondrial membrane (OMM indicating that protein receptors may be involved in the import process. However, RNAi against components of TOM (Tom40, Tom70, Tom22 or Tom20 by siRNA, individually or in combination, did not consistently change the amount of Bim on HeLa mitochondria, either at steady state or upon de novo-induction. In support of this, the individual or combined knock-downs of TOM receptors also failed to alter the susceptibility of HeLa cells to Bim-induced apoptosis. In isolated yeast mitochondria, lack of Tom70 or the TOM-components Tom20 or Tom22 alone did not affect the import of Bim into the outer mitochondrial membrane. In yeast, expression of Bim can sensitize the cells to Bax-dependent killing. This sensitization was unaffected by the absence of Tom70 or by an experimental reduction in Tom40. Although thus the physiological role of the Bim-TOM-interaction remains unclear, TOM complex components do not seem to be essential for Bim insertion into the OMM. Nevertheless, this association should be noted and considered when the regulation of Bim in other cells and situations is investigated.

  11. The pro-apoptotic BH3-only protein Bim interacts with components of the translocase of the outer mitochondrial membrane (TOM).

    Science.gov (United States)

    Frank, Daniel O; Dengjel, Jörn; Wilfling, Florian; Kozjak-Pavlovic, Vera; Häcker, Georg; Weber, Arnim

    2015-01-01

    The pro-apoptotic Bcl-2-family protein Bim belongs to the BH3-only proteins known as initiators of apoptosis. Recent data show that Bim is constitutively inserted in the outer mitochondrial membrane via a C-terminal transmembrane anchor from where it can activate the effector of cytochrome c-release, Bax. To identify regulators of Bim-activity, we conducted a search for proteins interacting with Bim at mitochondria. We found an interaction of Bim with Tom70, Tom20 and more weakly with Tom40, all components of the Translocase of the Outer Membrane (TOM). In vitro import assays performed on tryptically digested yeast mitochondria showed reduced Bim insertion into the outer mitochondrial membrane (OMM) indicating that protein receptors may be involved in the import process. However, RNAi against components of TOM (Tom40, Tom70, Tom22 or Tom20) by siRNA, individually or in combination, did not consistently change the amount of Bim on HeLa mitochondria, either at steady state or upon de novo-induction. In support of this, the individual or combined knock-downs of TOM receptors also failed to alter the susceptibility of HeLa cells to Bim-induced apoptosis. In isolated yeast mitochondria, lack of Tom70 or the TOM-components Tom20 or Tom22 alone did not affect the import of Bim into the outer mitochondrial membrane. In yeast, expression of Bim can sensitize the cells to Bax-dependent killing. This sensitization was unaffected by the absence of Tom70 or by an experimental reduction in Tom40. Although thus the physiological role of the Bim-TOM-interaction remains unclear, TOM complex components do not seem to be essential for Bim insertion into the OMM. Nevertheless, this association should be noted and considered when the regulation of Bim in other cells and situations is investigated.

  12. Cooperation of TOM and TIM23 complexes during translocation of proteins into mitochondria.

    Science.gov (United States)

    Waegemann, Karin; Popov-Čeleketić, Dušan; Neupert, Walter; Azem, Abdussalam; Mokranjac, Dejana

    2015-03-13

    Translocation of the majority of mitochondrial proteins from the cytosol into mitochondria requires the cooperation of TOM and TIM23 complexes in the outer and inner mitochondrial membranes. The molecular mechanisms underlying this cooperation remain largely unknown. Here, we present biochemical and genetic evidence that at least two contacts from the side of the TIM23 complex play an important role in TOM-TIM23 cooperation in vivo. Tim50, likely through its very C-terminal segment, interacts with Tom22. This interaction is stimulated by translocating proteins and is independent of any other TOM-TIM23 contact known so far. Furthermore, the exposure of Tim23 on the mitochondrial surface depends not only on its interaction with Tim50 but also on the dynamics of the TOM complex. Destabilization of the individual contacts reduces the efficiency of import of proteins into mitochondria and destabilization of both contacts simultaneously is not tolerated by yeast cells. We conclude that an intricate and coordinated network of protein-protein interactions involving primarily Tim50 and also Tim23 is required for efficient translocation of proteins across both mitochondrial membranes. Copyright © 2014 Elsevier Ltd. All rights reserved.

  13. Bottlenose dolphin Tursiops truncatus at São Tomé Island (São ...

    African Journals Online (AJOL)

    Although the bottlenose dolphin Tursiops truncatus is one of the most common cetacean species around São Tomé Island, Gulf of Guinea, little research has focused on this species in this region. This study investigated the population of bottlenose dolphins around São Tomé Island by estimating the minimum population ...

  14. Short Note New hope for the critically endangered São Tomé ...

    African Journals Online (AJOL)

    However, this new site lies outside the Ôbo Natural Park, São Tomé's only protected area, for which we alert the need to better protect its surroundings, which are relevant for many of the island's endemic species. Keywords: buffer zone, conservation, distribution, Ôbo Natural Park, playback, São Tomé and Príncipe

  15. Challenges and Opportunities: My Personal Journey. Tomás Rivera Lecture Series

    Science.gov (United States)

    Moran, Rachel F.

    2011-01-01

    Each year a distinguished scholar or prominent leader is selected to present the Tomás Rivera Lecture. Named in honor of the late Dr. Tomás Rivera, professor, scholar, poet, and former president of the University of California, Riverside, the American Association of Hispanics in Higher Education (AAHHE) is continuing this lecture at its annual…

  16. miR-126 is downregulated in cystic fibrosis airway epithelial cells and regulates TOM1 expression.

    LENUS (Irish Health Repository)

    Oglesby, Irene K

    2010-02-15

    Cystic fibrosis (CF) is one of the most common lethal genetic diseases in which the role of microRNAs has yet to be explored. Predicted to be regulated by miR-126, TOM1 (target of Myb1) has been shown to interact with Toll-interacting protein, forming a complex to regulate endosomal trafficking of ubiquitinated proteins. TOM1 has also been proposed as a negative regulator of IL-1beta and TNF-alpha-induced signaling pathways. MiR-126 is highly expressed in the lung, and we now show for the first time differential expression of miR-126 in CF versus non-CF airway epithelial cells both in vitro and in vivo. MiR-126 downregulation in CF bronchial epithelial cells correlated with a significant upregulation of TOM1 mRNA, both in vitro and in vivo when compared with their non-CF counterparts. Introduction of synthetic pre-miR-126 inhibited luciferase activity in a reporter system containing the full length 3\\'-untranslated region of TOM1 and resulted in decreased TOM1 protein production in CF bronchial epithelial cells. Following stimulation with LPS or IL-1beta, overexpression of TOM1 was found to downregulate NF-kappaB luciferase activity. Conversely, TOM1 knockdown resulted in a significant increase in NF-kappaB regulated IL-8 secretion. These data show that miR-126 is differentially regulated in CF versus non-CF airway epithelial cells and that TOM1 is a miR-126 target that may have an important role in regulating innate immune responses in the CF lung. To our knowledge, this study is the first to report of a role for TOM1 in the TLR2\\/4 signaling pathways and the first to describe microRNA involvement in CF.

  17. Tom Olaf Urb / intervjueerinud Siim Õ. Ilves

    Index Scriptorium Estoniae

    Urb, Tom Olaf, 1985-

    2016-01-01

    Muusik, produtsent, kirjanik ja näitleja Tom-Olaf Urb, lavanimega Reket, arutleb disaini teemal ja nimetab kümme disainieset, mis teda elus köitnud on. Eesti Hip-Hop auhindade jagamisel valiti Reketi "Tuule tee" 2015.a. parimaks kodumaiseks hip-hop albumiks

  18. Investigating the genetic basis of theory of mind (ToM): the role of catechol-O-methyltransferase (COMT) gene polymorphisms.

    Science.gov (United States)

    Xia, Haiwei; Wu, Nan; Su, Yanjie

    2012-01-01

    The ability to deduce other persons' mental states and emotions which has been termed 'theory of mind (ToM)' is highly heritable. First molecular genetic studies focused on some dopamine-related genes, while the genetic basis underlying different components of ToM (affective ToM and cognitive ToM) remain unknown. The current study tested 7 candidate polymorphisms (rs4680, rs4633, rs2020917, rs2239393, rs737865, rs174699 and rs59938883) on the catechol-O-methyltransferase (COMT) gene. We investigated how these polymorphisms relate to different components of ToM. 101 adults participated in our study; all were genetically unrelated, non-clinical and healthy Chinese subjects. Different ToM tasks were applied to detect their theory of mind ability. The results showed that the COMT gene rs2020917 and rs737865 SNPs were associated with cognitive ToM performance, while the COMT gene rs5993883 SNP was related to affective ToM, in which a significant gender-genotype interaction was found (p = 0.039). Our results highlighted the contribution of DA-related COMT gene on ToM performance. Moreover, we found out that the different SNP at the same gene relates to the discriminative aspect of ToM. Our research provides some preliminary evidence to the genetic basis of theory of mind which still awaits further studies.

  19. Lateral release of proteins from the TOM complex into the outer membrane of mitochondria.

    Science.gov (United States)

    Harner, Max; Neupert, Walter; Deponte, Marcel

    2011-07-15

    The TOM complex of the outer membrane of mitochondria is the entry gate for the vast majority of precursor proteins that are imported into the mitochondria. It is made up by receptors and a protein conducting channel. Although precursor proteins of all subcompartments of mitochondria use the TOM complex, it is not known whether its channel can only mediate passage across the outer membrane or also lateral release into the outer membrane. To study this, we have generated fusion proteins of GFP and Tim23 which are inserted into the inner membrane and, at the same time, are spanning either the TOM complex or are integrated into the outer membrane. Our results demonstrate that the TOM complex, depending on sequence determinants in the precursors, can act both as a protein conducting pore and as an insertase mediating lateral release into the outer membrane.

  20. STS-98 Crew Interview: Tom Jones

    Science.gov (United States)

    2001-01-01

    The STS-98 Mission Specialist Tom Jones is seen being interviewed. He answers questions about his inspiration to become an astronaut, his career path, and his training. He gives details on the mission's goals and significance, and the payload and hardware it brings to the International Space Station (ISS). Mr. Jones discusses his role in the mission's spacewalks and activities.

  1. Staging Henry Fielding: The Author-Narrator in Tom Jones On Screen

    OpenAIRE

    Løfaldli, Eli

    2017-01-01

    As recent adaptation theory has shown, classic-novel adaptation typically sets issues connected to authorship and literal and figurative ownership into play. This key feature of such adaptations is also central to the screen versions of Henry Fielding’s Tom Jones (1749). In much of Fielding’s fiction, the narrator, typically understood as an embodiment of Fielding himself, is a particularly prominent presence. The author-narrator in Tom Jones is no exception: not only is his presence strongly...

  2. Errors resulting from assuming opaque Lambertian clouds in TOMS ozone retrieval

    International Nuclear Information System (INIS)

    Liu, X.; Newchurch, M.J.; Loughman, R.; Bhartia, P.K.

    2004-01-01

    Accurate remote sensing retrieval of atmospheric constituents over cloudy areas is very challenging because of insufficient knowledge of cloud parameters. Cloud treatments are highly idealized in most retrieval algorithms. Using a radiative transfer model treating clouds as scattering media, we investigate the effects of assuming opaque Lambertian clouds and employing a Partial Cloud Model (PCM) on Total Ozone Mapping Spectrometer (TOMS) ozone retrievals, especially for tropical high-reflectivity clouds. Assuming angularly independent cloud reflection is good because the Ozone Retrieval Errors (OREs) are within 1.5% of the total ozone (i.e., within TOMS retrieval precision) when Cloud Optical Depth (COD)≥20. Because of Intra-Cloud Ozone Absorption ENhancement (ICOAEN), assuming opaque clouds can introduce large OREs even for optically thick clouds. For a water cloud of COD 40 spanning 2-12 km with 20.8 Dobson Unit (DU) ozone homogeneously distributed in the cloud, the ORE is 17.8 DU in the nadir view. The ICOAEN effect depends greatly on solar zenith angle, view zenith angle, and intra-cloud ozone amount and distribution. The TOMS PCM is good because negative errors from the cloud fraction being underestimated partly cancel other positive errors. At COD≤5, the TOMS algorithm retrieves approximately the correct total ozone because of compensating errors. With increasing COD up to 20-40, the overall positive ORE increases and is finally dominated by the ICOAEN effect. The ICOAEN effect is typically 5-13 DU on average over the Atlantic and Africa and 1-7 DU over the Pacific for tropical high-altitude (cloud top pressure ≤300 hPa) and high-reflectivity (reflectivity ≥ 80%) clouds. Knowledge of TOMS ozone retrieval errors has important implications for remote sensing of ozone/trace gases from other satellite instruments

  3. Tom Brown appointed Dean of Students

    OpenAIRE

    Williams, Meghan

    2007-01-01

    James Thomas "Tom" Brown, former senior associate dean of the Dean of Students office, has been appointed as the Dean of Students. The Dean of Students office is responsible for the coordination of student advocacy, new student orientation and parent programs, and responding to student emergencies in collaboration with Judicial Affairs, Residence Life, Cook Counseling Center, Schiffert Health Center, and other departments and agencies.

  4. Türkiye Ekonomisinde Sektörel Enerji Tüketiminin Ayrıştırma Yöntemiyle Analizi

    Directory of Open Access Journals (Sweden)

    Alper Yılmaz

    2016-12-01

    Full Text Available Bu çalışma 1970-2013 yılları arasında Türkiye ekonomisi için sektörel enerji tüketimini ayrıştırma yöntemiyle analiz etmeyi amaçlamaktadır. Çalışmanın sonuçlarına göre sektörel enerji tüketiminin çıktı ve yapısal etki nedeniyle arttığı, yoğunluk etkisi nedeniyle ise düştüğü görülür. Ayrıca diğer iki etkiye göre çıktı etkisi sektörel enerji tüketimi üzerinde en güçlü etkiye sahiptir. Sektörel enerji tüketiminin üretim artışı ile oldukça yakın ilişkili (doğrusal olduğu görülür. Benzer şekilde yapısal etkinin, Türkiye ekonomisindeki enerji yoğun sektörlerinin ağırlığının artmasına bağlı olarak sektörel enerji tüketimini arttırıcı yönde etki yaptığı görülür. Ancak yoğunluk etkisine bakıldığında 1980 sonrasında Türkiye ekonomisi enerji yoğunluğunun yavaş bir düşme eğilimi içinde olduğu görülür.

  5. El procesamiento informático de los materiales del Atlas Lingüístico de la Península Ibérica de Tomás Navarro Tomás

    OpenAIRE

    García Mouton, Pilar

    2010-01-01

    Estas páginas dan noticia de la puesta en marcha de un proyecto intramural del CSIC para elaborar y editar definitivamente, en soporte informático, los materiales del Atlas Lingüístico de la Península Ibérica, que Tomás Navarro Tomás dirigió en la primera mitad del siglo XX.

  6. Empathy, ToM, and self-other differentiation: an fMRI study of internal states.

    Science.gov (United States)

    Reniers, Renate L E P; Völlm, Birgit A; Elliott, Rebecca; Corcoran, Rhiannon

    2014-02-01

    This study used functional magnetic resonance imaging to examine the neural substrates of empathy, Theory of Mind (ToM), and self-other differentiation involved in the adaptive understanding of people's internal states. Three conditions were distinguished in both sad and neutral (no obvious emotion) contexts. The empathy condition involved imagining what another person is feeling while the more cognitively loaded ToM condition involved imagining what would make another person feel better. The self-reference condition required participants to imagine how they would feel in someone else's situation. Areas previously implicated in empathy, ToM, and self-other differentiation were identified within the different conditions, regardless of emotional context. Specifically, the frontal and temporal poles responded more strongly for ToM than for empathy. The self-reference condition was associated with stronger dorsolateral prefrontal response than the empathy condition, while the reverse comparison revealed a stronger role for right frontal pole. Activations in frontal pole and orbitofrontal cortex were shared between the three conditions. Contrasts of parameter estimates demonstrated modulation by emotional context. The findings of common and differential patterns of responding observed in prefrontal and temporal regions suggest that within the social cognition network empathy, ToM and self-other differentiation have distinct roles that are responsive to context.

  7. An Expanded UV Irradiance Database from TOMS Including the Effects of Ozone, Clouds, and Aerosol Attenuation

    Science.gov (United States)

    Herman, J.; Krotkov, N.

    2003-01-01

    The TOMS UV irradiance database (1978 to 2003) has been expanded to include five new products (noon irradiance at 305,310,324, and 380 nm, and noon erythemal-weighted irradiance), in addition to the existing erythemal daily exposure, that permit direct comparisons with ground-based measurements from spectrometers and broadband instruments. The new data are available on http://toms.gsfc.nasa.gov/>http://toms.gsfc.nasa.gov. Comparisons of the TOMS estimated irradiances with ground-based instruments are given along with a review of the sources of known errors, especially the recent improvements in accounting for aerosol attenuation. Trend estimations from the new TOMS irradiances permit the clear separation of changes caused by ozone and those caused by aerosols and clouds. Systematic differences in cloud cover are shown to be the most important factor in determining regional differences in UV radiation reaching the ground for locations at the same latitude (e.g., the summertime differences between Australia and the US southwest).

  8. Isepäine iseõppija Tom Dixon

    Index Scriptorium Estoniae

    2007-01-01

    Inglise disainerist Tom Dixonist (sünd. 1959) ja tema loomingust. 1998. aastast UK disainistuudio juht mööblifirma Habitat juures, mööblitööstuse Artek loominguline direktor. Aprillis 2007 esines Milano mööblimessil vaskvalgustite kollektsiooniga ja Triennale pargis koostöös Shigeru Baniga Arteki paviljoniga

  9. Annual Quality Assurance Conference Files by Tom Mancuso

    Science.gov (United States)

    25th Annual Quality Assurance Conference. Abstract: Learn about the NEW EPA Method 325b for Refinery Fence Line Monitoring and TO-17 Extended for Soil Gas by Tom Mancuso and Abstract: Success Using Alternate Carrier Gases for Volatile Methods

  10. Tom Russell: "Õpetajakoolitust tuleks alustada praktikast" / Liisa Lumiste

    Index Scriptorium Estoniae

    Lumiste, Liisa

    2013-01-01

    Eduko programmi raames Tallinna Ülikoolis toimunud avalikul loengul rääkis Kanada kasvatusteadlane Tom Russell praktika tähtsusest õpetajakoolituses ja viis läbi meistriklassi õpetajakoolituse õppejõududele

  11. Systematic Comparison of Brain Imaging Meta-Analyses of ToM with vPT.

    Science.gov (United States)

    Arora, Aditi; Schurz, Matthias; Perner, Josef

    2017-01-01

    In visual perspective taking (vPT) one has to concern oneself with what other people see and how they see it. Since seeing is a mental state, developmental studies have discussed vPT within the domain of "theory of mind (ToM)" but imaging studies have not treated it as such. Based on earlier results from several meta-analyses, we tested for the overlap of visual perspective taking studies with 6 different kinds of ToM studies: false belief, trait judgments, strategic games, social animations, mind in the eyes, and rational actions. Joint activation was observed between the vPT task and some kinds of ToM tasks in regions involving the left temporoparietal junction (TPJ), anterior precuneus, left middle occipital gyrus/extrastriate body area (EBA), and the left inferior frontal and precentral gyrus. Importantly, no overlap activation was found for the vPT tasks with the joint core of all six kinds of ToM tasks. This raises the important question of what the common denominator of all tasks that fall under the label of "theory of mind" is supposed to be if visual perspective taking is not one of them.

  12. Sam37 is crucial for formation of the mitochondrial TOM-SAM supercomplex, thereby promoting β-barrel biogenesis.

    Science.gov (United States)

    Wenz, Lena-Sophie; Ellenrieder, Lars; Qiu, Jian; Bohnert, Maria; Zufall, Nicole; van der Laan, Martin; Pfanner, Nikolaus; Wiedemann, Nils; Becker, Thomas

    2015-09-28

    Biogenesis of mitochondrial β-barrel proteins requires two preprotein translocases, the general translocase of the outer membrane (TOM) and the sorting and assembly machinery (SAM). TOM and SAM form a supercomplex that promotes transfer of β-barrel precursors. The SAM core complex contains the channel protein Sam50, which cooperates with Sam35 in precursor recognition, and the peripheral membrane protein Sam37. The molecular function of Sam37 has been unknown. We report that Sam37 is crucial for formation of the TOM-SAM supercomplex. Sam37 interacts with the receptor domain of Tom22 on the cytosolic side of the mitochondrial outer membrane and links TOM and SAM complexes. Sam37 thus promotes efficient transfer of β-barrel precursors to the SAM complex. We conclude that Sam37 functions as a coupling factor of the translocase supercomplex of the mitochondrial outer membrane. © 2015 Wenz et al.

  13. Clean Coal Power at Toms Creek

    International Nuclear Information System (INIS)

    Schmid, M.R.

    1993-01-01

    On October 20, 1992 the US Department of Energy (DOE), through the Morgantown Energy Technology Center, entered into Cooperative Agreement DE-FC-21-93MC92444 with TAMCO Power Partners to implement the Toms Creek Integrated Gasification Combined - Cycle Demonstration Project. The process design is proceeding as scheduled, and a draft Environmental Information Volume has been produced. The overall project schedule, however, may have to be adjusted when the Power Sales Agreement has been finalized

  14. Theory of mind broad and narrow: reasoning about social exchange engages ToM areas, precautionary reasoning does not.

    Science.gov (United States)

    Ermer, Elsa; Guerin, Scott A; Cosmides, Leda; Tooby, John; Miller, Michael B

    2006-01-01

    Baron-Cohen (1995) proposed that the theory of mind (ToM) inference system evolved to promote strategic social interaction. Social exchange--a form of co-operation for mutual benefit--involves strategic social interaction and requires ToM inferences about the contents of other individuals' mental states, especially their desires, goals, and intentions. There are behavioral and neuropsychological dissociations between reasoning about social exchange and reasoning about equivalent problems tapping other, more general content domains. It has therefore been proposed that social exchange behavior is regulated by social contract algorithms: a domain-specific inference system that is functionally specialized for reasoning about social exchange. We report an fMRI study using the Wason selection task that provides further support for this hypothesis. Precautionary rules share so many properties with social exchange rules--they are conditional, deontic, and involve subjective utilities--that most reasoning theories claim they are processed by the same neurocomputational machinery. Nevertheless, neuroimaging shows that reasoning about social exchange activates brain areas not activated by reasoning about precautionary rules, and vice versa. As predicted, neural correlates of ToM (anterior and posterior temporal cortex) were activated when subjects interpreted social exchange rules, but not precautionary rules (where ToM inferences are unnecessary). We argue that the interaction between ToM and social contract algorithms can be reciprocal: social contract algorithms requires ToM inferences, but their functional logic also allows ToM inferences to be made. By considering interactions between ToM in the narrower sense (belief-desire reasoning) and all the social inference systems that create the logic of human social interaction--ones that enable as well as use inferences about the content of mental states--a broader conception of ToM may emerge: a computational model embodying

  15. Extension of Tom Booth's Modified Power Method for Higher Eigen Modes

    International Nuclear Information System (INIS)

    Zhang, Peng; Lee, Hyunsuk; Lee, Deokjung

    2015-01-01

    A possible technique to get the even higher modes is suggested, but it is difficult to be applied practically. In this paper, a general solution strategy is proposed, which can extend Tom Booth's modified power method to get the higher Eigenmodes and there is no limitation about the number of Eigenmodes that can be obtained with this method. In this paper, a general solution strategy is proposed, which can extend Tom Booth's modified power method to get the higher Eigenmodes and there is no limitation about the number of Eigenmodes that can be obtained with this method. It is more practical than the original solution strategy that Tom Booth proposed. The implementation of the method in Monte Carlo code shows significant advantages comparing to the original power method

  16. Differential Regulation of Synaptic Vesicle Tethering and Docking by UNC-18 and TOM-1.

    Science.gov (United States)

    Gracheva, Elena O; Maryon, Ed B; Berthelot-Grosjean, Martine; Richmond, Janet E

    2010-01-01

    The assembly of SNARE complexes between syntaxin, SNAP-25 and synaptobrevin is required to prime synaptic vesicles for fusion. Since Munc18 and tomosyn compete for syntaxin interactions, the interplay between these proteins is predicted to be important in regulating synaptic transmission. We explored this possibility, by examining genetic interactions between C. elegans unc-18(Munc18), unc-64(syntaxin) and tom-1(tomosyn). We have previously demonstrated that unc-18 mutants have reduced synaptic transmission, whereas tom-1 mutants exhibit enhanced release. Here we show that the unc-18 mutant release defect is associated with loss of two morphologically distinct vesicle pools; those tethered within 25 nm of the plasma membrane and those docked with the plasma membrane. In contrast, priming defective unc-13 mutants accumulate tethered vesicles, while docked vesicles are greatly reduced, indicating tethering is UNC-18-dependent and occurs in the absence of priming. C. elegans unc-64 mutants phenocopy unc-18 mutants, losing both tethered and docked vesicles, whereas overexpression of open syntaxin preferentially increases vesicle docking, suggesting UNC-18/closed syntaxin interactions are responsible for vesicle tethering. Given the competition between vertebrate tomosyn and Munc18, for syntaxin binding, we hypothesized that C. elegans TOM-1 may inhibit both UNC-18-dependent vesicle targeting steps. Consistent with this hypothesis, tom-1 mutants exhibit enhanced UNC-18 plasma membrane localization and a concomitant increase in both tethered and docked synaptic vesicles. Furthermore, in tom-1;unc-18 double mutants the docked, primed vesicle pool is preferentially rescued relative to unc-18 single mutants. Together these data provide evidence for the differential regulation of two vesicle targeting steps by UNC-18 and TOM-1 through competitive interactions with syntaxin.

  17. Differential regulation of synaptic vesicle tethering and docking by UNC-18 and TOM-1

    Directory of Open Access Journals (Sweden)

    Elena O Gracheva

    2010-10-01

    Full Text Available The assembly of SNARE complexes between syntaxin, SNAP-25 and synaptobrevin is required to prime synaptic vesicles for fusion. Since Munc18 and tomosyn compete for syntaxin interactions, the interplay between these proteins is predicted to be important in regulating synaptic transmission. We explored this possibility, by examining genetic interactions between C. elegans unc-18(Munc18, unc-64(syntaxin and tom-1(tomosyn. We have previously demonstrated that unc-18 mutants have reduced synaptic transmission, whereas tom-1 mutants exhibit enhanced release. Here we show that the unc-18 mutant release defect is associated with loss of two morphologically distinct vesicle pools; those tethered within 25nm of the plasma membrane and those docked with the plasma membrane. In contrast, priming defective unc-13 mutants accumulate tethered vesicles, while docked vesicles are greatly reduced, indicating tethering is UNC-18-dependent and occurs in the absence of priming. C. elegans unc-64 mutants phenocopy unc-18 mutants, losing both tethered and docked vesicles, whereas overexpression of open syntaxin preferentially increases vesicle docking, suggesting UNC-18/closed syntaxin interactions are responsible for vesicle tethering. Given the competition between vertebrate tomosyn and Munc18, for syntaxin binding, we hypothesized that C. elegans TOM-1 may inhibit both UNC-18-dependent vesicle targeting steps. Consistent with this hypothesis, tom-1 mutants exhibit enhanced UNC-18 plasma membrane localization and a concomitant increase in both tethered and docked synaptic vesicles. Furthermore, in tom-1;unc-18 double mutants the docked, primed vesicle pool is preferentially rescued relative to unc-18 single mutants. Together these data provide evidence for the differential regulation of two vesicle targeting steps by UNC-18 and TOM-1 through competitive interactions with syntaxin

  18. Technical evaluation of Tom Scurry Associates: Model PM-203 doorway monitor

    International Nuclear Information System (INIS)

    1978-07-01

    Under a basic assignment by the Office of Safeguards and Security, the Tom Scurry Associates Model PM-203 Personnel Doorway SNM Monitor manufactured by Tom Scurry Associates was evaluated by LASL Group Q-2 against the DOE Personnel Doorway Monitor standards. During the evaluation, a small change was required in detector shielding to eliminate low sensitivity areas at the portal sides. With the modified shielding described, the PM-203 meets the Office of Safeguards and Security SNM doorway monitor specifications for detecting either 235 U or 239 Pu-- 233 U. This system is also capable of monitoring 238 Pu

  19. Performance and Carcass characteristics of broad breasted bronze toms fed radappertized Diet

    International Nuclear Information System (INIS)

    Farag, El-Din.M.H.; Mohamed, F.A.

    1999-01-01

    The effect of irradiated complete diets at dose level of 25 KGy was studied in broad breasted bronze tome evaluating their growing performances as well as characteristics of the carcasses. Two experimental groups received irradiated and non irradiated diets for 18 weeks (from the 5 t h to the 23 r d week of age). Four toms per treatment at the age of 23 weeks were slaughtered and the carcass was dissected. Radappertized diets improved body weight gain, feed consumption and feed conversion and reduced mortality rate. No significant differences were observed between toms fed processed and non processed diets on carcasses components, while the gizzard weight was greater for those fed the processed diets. Dressing and drawn weights in toms fed processed diets were 3% higher than in those fed non processed diets. The results suggest that sterilization of turkeys feed may have a beneficial effect on the body weight and deed conversion of turkeys consuming these diets without harmful effect on the bird

  20. Nimble Negotiators: How Theory of Mind (ToM) Interconnects with Persuasion Skills in Children with and without ToM Delay

    Science.gov (United States)

    Peterson, Candida C.; Slaughter, Virginia; Wellman, Henry M.

    2018-01-01

    Persuasion is an essential social skill. Yet its development and underpinnings are poorly understood. In 2 studies, a total of 167 children aged 3 to 12 years took theory of mind (ToM) tests and participated in unscripted, seminaturalistic persuasive conversations. Children were typically developing (TD) or had deafness or autism spectrum disorder…

  1. Design, fabrication and performance of the 10-in TOM HPD

    CERN Document Server

    Braem, André; Joram, C; Séguinot, Jacques; Weilhammer, P; Giunta, M; Malakhov, N; Menzione, A; Pegna, R; Piccioli, A; Raffaelli, F; Sartori, G

    2004-01-01

    The first sealed TOM Hybrid Photon Detector (HPD) with 10-in. diameter has been fabricated and successfully tested at CERN. This HPD has a spherical entrance window and a bialkali photocathode. The fountain focusing optics produces a demagnified image (D = 4) on the round segmented silicon sensor. The signals of the 2048 cells are read out through analog front-end electronics encapsulated in the vacuum envelope. We report on the design, fabrication technique and the experimental results obtained with laboratory test benches. The large TOM HPD is a prototype tube developed for the CLUE cosmic ray experiment. The final tubes, now under development, will be equipped with a solar-blind Rb//2Te photocathode and self triggering front-end electronics.

  2. Design, fabrication and performance of the 10-in. TOM HPD

    International Nuclear Information System (INIS)

    Braem, A.; Chesi, E.; Joram, C.; Seguinot, J.; Weilhammer, P.; Giunta, M.; Malakhov, N.; Menzione, A.; Pegna, R.; Piccioli, A.; Raffaelli, F.; Sartori, G.

    2004-01-01

    The first sealed TOM Hybrid Photon Detector (HPD) with 10-in. diameter has been fabricated and successfully tested at CERN. This HPD has a spherical entrance window and a bialkali photocathode. The fountain focusing optics produces a demagnified image (D=4) on the round segmented silicon sensor. The signals of the 2048 cells are read out through analog front-end electronics encapsulated in the vacuum envelope. We report on the design, fabrication technique and the experimental results obtained with laboratory test benches. The large TOM HPD is a prototype tube developed for the CLUE cosmic ray experiment. The final tubes, now under development, will be equipped with a solar-blind Rb 2 Te photocathode and self triggering front-end electronics

  3. 77 FR 57477 - Delegation of Certain Functions and Authority Under Section 5(a) of the Tom Lantos Block Burmese...

    Science.gov (United States)

    2012-09-17

    ...--Delegation of Certain Functions and Authority Under Section 5(a) of the Tom Lantos Block Burmese Junta's Anti... 5(a) of the Tom Lantos Block Burmese Junta's Anti-Democratic Efforts Act of 2008 Memorandum for the... section 5(a)(2) of the Tom Lantos Block Burmese Junta's Anti- Democratic Efforts Act of 2008 (Public Law...

  4. Distinct forms of mitochondrial TOM-TIM supercomplexes define signal-dependent states of preprotein sorting.

    Science.gov (United States)

    Chacinska, Agnieszka; van der Laan, Martin; Mehnert, Carola S; Guiard, Bernard; Mick, David U; Hutu, Dana P; Truscott, Kaye N; Wiedemann, Nils; Meisinger, Chris; Pfanner, Nikolaus; Rehling, Peter

    2010-01-01

    Mitochondrial import of cleavable preproteins occurs at translocation contact sites, where the translocase of the outer membrane (TOM) associates with the presequence translocase of the inner membrane (TIM23) in a supercomplex. Different views exist on the mechanism of how TIM23 mediates preprotein sorting to either the matrix or inner membrane. On the one hand, two TIM23 forms were proposed, a matrix transport form containing the presequence translocase-associated motor (PAM; TIM23-PAM) and a sorting form containing Tim21 (TIM23(SORT)). On the other hand, it was reported that TIM23 and PAM are permanently associated in a single-entity translocase. We have accumulated distinct transport intermediates of preproteins to analyze the translocases in their active, preprotein-carrying state. We identified two different forms of active TOM-TIM23 supercomplexes, TOM-TIM23(SORT) and TOM-TIM23-PAM. These two supercomplexes do not represent separate pathways but are in dynamic exchange during preprotein translocation and sorting. Depending on the signals of the preproteins, switches between the different forms of supercomplex and TIM23 are required for the completion of preprotein import.

  5. Tom Rüütel: Tööandjal on igal juhul kasud sees / intervjueerinud Helen Kask

    Index Scriptorium Estoniae

    Rüütel, Tom

    2013-01-01

    Kui oluliseks peab Tom töötamist ning millisena näeb ta tööandjate suhtumst erivajadusega töötajasse? Millised on Tomi mõtted seoses töövõimetoetuse (TVK) reformiga? Tom Rüütel õpib Tallinna Ülikoolis magistrantuuri teisel kursusel rakenduslikku sotsiaaltööd

  6. 77 FR 51912 - Safety Zone; Tom Lyons Productions Fireworks, Long Island Sound, Sands Point, NY

    Science.gov (United States)

    2012-08-28

    ... DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 165 [Docket Number USCG-2012-0618] RIN 1625-AA00 Safety Zone; Tom Lyons Productions Fireworks, Long Island Sound, Sands Point, NY AGENCY.... 165.T01-0618 to read as follows: Sec. 165.T01-0618 Safety Zone; Tom Lyons Productions Fireworks, Long...

  7. Genealogy of John and Charles Bell: their relationship with the children of Charles Shaw of Ayr.

    Science.gov (United States)

    Kaufman, M

    2005-11-01

    The Reverend William Bell had six children who survived infancy. Two of his sons entered the legal profession and two other sons became distinguished anatomists and surgeons--John Bell, said for 20 years to have been the leading operating surgeon in Britain and throughout the world--and Sir Charles Bell, possibly the most distinguished anatomist and physiologist of his day. Information is not known about the fifth son or their sister. Charles Shaw, a lawyer of Ayr, had four sons and two daughters who survived infancy. Two of his sons, John and Alexander, became anatomists and later surgeons at the Middlesex Hospital, and both worked closely with Charles Bell at the Great Windmill Street School of Anatomy. His third son entered the law and his fourth son became a distinguished soldier. The two daughters of Charles Shaw married into the Bell family: Barbara married George Joseph Bell and Marion married Mr (later Sir) Charles Bell.

  8. Micro-Tom Tomato as an Alternative Plant Model System: Mutant Collection and Efficient Transformation.

    Science.gov (United States)

    Shikata, Masahito; Ezura, Hiroshi

    2016-01-01

    Tomato is a model plant for fruit development, a unique feature that classical model plants such as Arabidopsis and rice do not have. The tomato genome was sequenced in 2012 and tomato is becoming very popular as an alternative system for plant research. Among many varieties of tomato, Micro-Tom has been recognized as a model cultivar for tomato research because it shares some key advantages with Arabidopsis including its small size, short life cycle, and capacity to grow under fluorescent lights at a high density. Mutants and transgenic plants are essential materials for functional genomics research, and therefore, the availability of mutant resources and methods for genetic transformation are key tools to facilitate tomato research. Here, we introduce the Micro-Tom mutant database "TOMATOMA" and an efficient transformation protocol for Micro-Tom.

  9. Transcultural differences in brain activation patterns during theory of mind (ToM) task performance in Japanese and Caucasian participants.

    Science.gov (United States)

    Koelkebeck, Katja; Hirao, Kazuyuki; Kawada, Ryousaku; Miyata, Jun; Saze, Teruyasu; Ubukata, Shiho; Itakura, Shoji; Kanakogi, Yasuhiro; Ohrmann, Patricia; Bauer, Jochen; Pedersen, Anya; Sawamoto, Nobukatsu; Fukuyama, Hidenao; Takahashi, Hidehiko; Murai, Toshiya

    2011-01-01

    Theory of mind (ToM) functioning develops during certain phases of childhood. Factors such as language development and educational style seem to influence its development. Some studies that have focused on transcultural aspects of ToM development have found differences between Asian and Western cultures. To date, however, little is known about transcultural differences in neural activation patterns as they relate to ToM functioning. The aim of our study was to observe ToM functioning and differences in brain activation patterns, as assessed by functional magnetic resonance imaging (fMRI). This study included a sample of 18 healthy Japanese and 15 healthy Caucasian subjects living in Japan. We presented a ToM task depicting geometrical shapes moving in social patterns. We also administered questionnaires to examine empathy abilities and cultural background factors. Behavioral data showed no significant group differences in the subjects' post-scan descriptions of the movies. The imaging results displayed stronger activation in the medial prefrontal cortex (MPFC) in the Caucasian sample during the presentation of ToM videos. Furthermore, the task-associated activation of the MPFC was positively correlated with autistic and alexithymic features in the Japanese sample. In summary, our results showed evidence of culturally dependent sociobehavioral trait patterns, which suggests that they have an impact on brain activation patterns during information processing involving ToM.

  10. Culture of the Tomato Micro-Tom Cultivar in Greenhouse.

    Science.gov (United States)

    Rothan, Christophe; Just, Daniel; Fernandez, Lucie; Atienza, Isabelle; Ballias, Patricia; Lemaire-Chamley, Martine

    2016-01-01

    Micro-Tom tomato cultivar is particularly adapted to the development of genomic approaches in tomato. Here, we describe the culture of this plant in greenhouse, including climate regulation, seed sowing and watering, vegetative development, plant maintenance, including treatment of phytosanitary problems, and reproductive development.

  11. Tom Bissel, Voglia di vincere/Extra Lives

    Directory of Open Access Journals (Sweden)

    Ambra Agnoletto

    2013-03-01

    Full Text Available Leggere il libro di Tom Bissell Extra lives: Why Video Games Matter, tradotto in Italia con il titolo Voglia di vincere, è stata un’impresa. L’impresa di qualcuno abituato a muoversi in ambito cinematografico e musicale, ma che affronta con l’entusiasmo e le incertezze del neofita i videogames e tutto ciò che riguarda la sfera videoludica, nei suoi aspetti creativi, estetici, di design e meccanica di gioco.

  12. TOMS EP UV Aerosol Index Daily and Monthly Zonal Means V008 (TOMSEPL3zaer) at GES DISC

    Data.gov (United States)

    National Aeronautics and Space Administration — This data product contains TOMS/EP UV Aerosol Index Daily and Monthly Zonal Means Version 8 data in ASCII format.The Total Ozone Mapping Spectrometer (TOMS) Version...

  13. Constructing a coherent long-term global total ozone climatology from the BUV, MFR, and SBUV/TOMS data sets

    International Nuclear Information System (INIS)

    Ellis, J.S.; Luther, F.M.

    1986-02-01

    The backscatter ultraviolet spectrometer (BUV) aboard the NIMBUS 4 satellite provided global ozone data until mid-1977. The Total Ozone Mapping Spectrometer (TOMS) and Solar Backscattered Ultraviolet (SBUV) instrument aboard the NIMBUS 7 satellite began providing global ozone in November 1978. The only satellite derived global total ozone data available between the termination of the BUV data and the startup of the SBUV/TOMS data is that from the Multichannel Filter Radiometer (MFR) instrument aboard the Defense Meteorological Satellite Program (DMSP) series of satellites. The MFR and the SBUV/TOMS data are compared during the data overlap period in order to determine how well the MFR data might be used to represent the SBUV/TOMS and BUV data during the data gap period. 5 refs., 3 figs., 3 tabs

  14. AuTom: a novel automatic platform for electron tomography reconstruction

    KAUST Repository

    Han, Renmin; Wan, Xiaohua; Wang, Zihao; Hao, Yu; Zhang, Jingrong; Chen, Yu; Gao, Xin; Liu, Zhiyong; Ren, Fei; Sun, Fei; Zhang, Fa

    2017-01-01

    -friendly interface and auxiliary designs for file management and workflow management, in which fiducial marker-based datasets and marker-free datasets are addressed with totally different subprocesses. With all of these features, AuTom can serve as a convenient

  15. ROMS/TOMS Tangent Linear and Adjoint Models: Testing and Applications

    National Research Council Canada - National Science Library

    Miller, Arthur J; Cornuelle, Bruce D

    2004-01-01

    ... (Regional Ocean Modeling System/Terrain-Following Ocean Modeling System) that is suitable for general use by the ROMS/TOMS community and to develop computational platforms based on the TLM and ADM for 4D variational data assimilation (4DVar...

  16. Factorial structure of the 'ToM Storybooks': A test evaluating multiple components of Theory of Mind.

    Science.gov (United States)

    Bulgarelli, Daniela; Testa, Silvia; Molina, Paola

    2015-06-01

    This study examined the factorial structure of the Theory of Mind (ToM) Storybooks, a comprehensive 93-item instrument tapping the five components in Wellman's model of ToM (emotion recognition, understanding of desire and beliefs, ability to distinguish between physical and mental entities, and awareness of the link between perception and knowledge). A sample of 681 three- to eight-year-old Italian children was divided into three age groups to assess whether factorial structure varied across different age ranges. Partial credit model analysis was applied to the data, leading to the empirical identification of 23 composite variables aggregating the ToM Storybooks items. Confirmatory factor analysis was then conducted on the composite variables, providing support for the theoretical model. There were partial differences in the specific composite variables making up the dimensions for each of the three age groups. A single test evaluating distinct dimensions of ToM is a valuable resource for clinical practice which may be used to define differential profiles for specific populations. © 2014 The British Psychological Society.

  17. Training Preschoolers on First-Order False Belief Understanding: Transfer on Advanced ToM Skills and Metamemory

    Science.gov (United States)

    Lecce, Serena; Bianco, Federica; Demicheli, Patrizia; Cavallini, Elena

    2014-01-01

    This study investigated the relation between theory of mind (ToM) and metamemory knowledge using a training methodology. Sixty-two 4- to 5-year-old children were recruited and randomly assigned to one of two training conditions: A first-order false belief (ToM) and a control condition. Intervention and control groups were equivalent at pretest for…

  18. SAFARI 2000 TOMS Aerosol Index Data, Southern Africa, Dry Season 2000

    Data.gov (United States)

    National Aeronautics and Space Administration — ABSTRACT: Daily Aerosol Index (AI) data from Earth Probe (EP) Total Ozone Mapping Spectrometer (TOMS) for the period of August 12-September 25, 2000 were processed...

  19. Tropical easterly jet located using TOMS data

    Science.gov (United States)

    Bolhofer, William C.

    1987-01-01

    The formative stages of the onset of the 1979 southwest monsoon was marked by a WNW-ESE oriented band of marine convection over the South Arabian Sea. This convection was first observed on June 10, 1979 using satellite cloud imagery. The marine convection appeared during a major acceleration of the upper troposphere easterly wind field. A composite vertical meridional cross-section of upper level winds for June 11, revealed the core of the Tropical Easterly Jet (TEJ) at 115 mb, 9.5 deg N. Time analysis of the upper level wind field over the Tropical Wind Observing Ship (TWOS) polygon show a lowering of both the pressure level of maximum wind and tropopause level with acceleration of the upper level easterlies. The tropopause was as much as 20 mb lower on the equatorial side of the TEJ. Streamline analysis of the maximum observed easterly winds over India did not reveal the horizontal position of the TEJ. Careful analysis of Total Ozone Mapping Spectrometer (TOMS) data for June 11, 1979 showed relatively high values of ozone south of India. It was observed that the latitudinal position of the TEJ on June 11, at approximately 70 deg E coincided with the northern edge of relatively high ozone values. Using this as a reference, the TEJ core was identified as far as NE Bay of Bengal (the limits of the available TOMS data).

  20. Hydrodynamic Aspects of the Toms Effect

    Science.gov (United States)

    Strel‧nikova, S. A.; Tkachenko, G. V.; Uryukov, B. A.

    2015-11-01

    The physicomathematical model of migration of polymers in a liquid turbulent flow in a pipe is based on a comparison of forces transverse to the motion of the mainstream flow: the Saffman, Magnus, and turbophoresis forces. It has been shown that the polymer particles are grouped near a certain boundary within the limits of the boundary layer. On this basis, the authors have made assumptions on the mechanism of suppression of turbulent pulsations and decrease in the viscous friction near the wall, which makes up the Toms effect. The proposed model satisfies, at least, qualitatively, various actually observed manifestations of the effect.

  1. Hydrology and Coastal Morphology at São Tomé

    NARCIS (Netherlands)

    Giardino, A.; Bettencourt, S.; Carvalho, A.; Filatova, Tatiana; de Keizer, O.; Schellekens, J.; Ottow, B.

    2012-01-01

    The Democratic Republic of São Tomé and Principe is an archipelago comprised of two main islands and several islets located in the Gulf of Guinea 350 km off the west coast of Africa. Villages of in the archipelago are built close to the coastline and have historically suffered from high rates of

  2. Ayrıntılandırma Olasılığı Modeli ve Uygulama Alanları

    OpenAIRE

    Kıymalıoğlu, Aslıhan

    2014-01-01

    İkna kavramını açıklayan önemli modellerden biri, ikna sürecinde merkezi ve çevresel ikna yolu olmak üzere iki süreç bulunduğunu savunan Ayrıntılandırma Olasılığı Modeli’dir. Türkçe yazında modeli kapsamlı bir şekilde ele alan bir çalışmaya rastlanılmamış olması dolayısıyla, modelin detaylı anlatımını ve modelle ilgili literatür taramasını içeren çalışmanın bu konuda bir boşluğu doldurduğu düşünülmektedir. Yapılan literatür taraması bulguları modelin en fazla pazarlama ve reklam alanlarındaki...

  3. Voyeuristi alla finestra: Peeping Tom, dalla leggenda al cinema

    Directory of Open Access Journals (Sweden)

    Laura Staiano

    2015-01-01

    Full Text Available This essay deals with voyeuristic attitudes and ʹscopic powerʹ, i.e. the power to gaze at forbidden things and people without being seen. Indeed, its object par excellence coincides with female nakedness, while its subject is an invisible masculinity, which takes delight in looking. The paper is based on a study of the Anglo-Saxon legend of Lady Godiva and it is strictly connected with the subject of my dissertation in progress – metaphorical and physical blindness in 18th century French literature (since several voyeurs got blind because of their instincts and desires. Lady Godiva’s voyeur, called Peeping Tom, is struck blind for having looked out of his window and seen the noblewoman riding naked. This legend has inspired many artists in different fields, and nowadays its heroine is very famous and venerated. In particular, this essay focuses on the relation between this legend and compulsive looking (or scopophilia in two renowned films, Rear Window by Alfred Hitchcock, and Peeping Tom by Michael Powell.

  4. Santo Tomás y los demás

    Directory of Open Access Journals (Sweden)

    Alfonso Rincón

    1988-10-01

    Full Text Available La filosofia del medioevo. VIII Coloquio de la Sociedad Colombiana de Filosofia. J.A. Díaz, J.P. Margot, A.L. Gómez, E. Lákatos, A. Cárdenas, G. Soto, D. Herrera, A. Papacchini, J. Zabalza. Biblioteca Colombiana de Filosofía, Universidad de Santo Tomás, Bogotá, 1987, 138 págs.

  5. Polypeptide Translocation Through the Mitochondrial TOM Channel: Temperature-Dependent Rates at the Single-Molecule Level.

    Science.gov (United States)

    Mahendran, Kozhinjampara R; Lamichhane, Usha; Romero-Ruiz, Mercedes; Nussberger, Stephan; Winterhalter, Mathias

    2013-01-03

    The TOM protein complex facilitates the transfer of nearly all mitochondrial preproteins across outer mitochondrial membranes. Here we characterized the effect of temperature on facilitated translocation of a mitochondrial presequence peptide pF1β. Ion current fluctuations analysis through single TOM channels revealed thermodynamic and kinetic parameters of substrate binding and allowed determining the energy profile of peptide translocation. The activation energy for the on-rate and off-rate of the presequence peptide into the TOM complex was symmetric with respect to the electric field and estimated to be about 15 and 22 kT per peptide. These values are above that expected for free diffusion of ions in water (6 kT) and reflect the stronger interaction in the channel. Both values are in the range for typical enzyme kinetics and suggest one process without involving large conformational changes within the channel protein.

  6. Effect of phosphate treatments on microbiological, physicochemical changes of spent hen muscle marinated with Tom Yum paste during chilled storage.

    Science.gov (United States)

    Wongwiwat, Pirinya; Wattanachant, Saowakon; Siripongvutikorn, Sunisa

    2010-06-01

    This research aimed to study the effect of phosphate on quality of ready-to-cook spent hen muscle marinated with Tom Yum paste, a famous Thai food made from chilli, lime leaves and garcinia (pH 2.5-2.9). The effects of phosphate treatments (phosphate types, soaking time, and phosphate concentration) on physical characteristics of spent hen muscle in high acid condition were investigated. Quality changes of muscles pretreated with or without phosphate and marinated with Tom Yum paste were determined during storage at 4 degrees C for 30 days. The acidified muscle pretreated with 40 g L(-1) sodium tripolyphosphate for 10 h had the highest marinade absorption, and the lowest cooking loss and shear force among all treatment samples. Microstructures of acidified muscle pretreated with and without sodium tripolyphosphate showed significant swelling with larger fibre diameter. Phosphate pretreatment had no influence on cooking loss, shear force and thiobarbituric acid reactive substance values of Tom Yum marinated muscle during storage. Tom Yum marination with phosphate pretreatment caused a higher increase in psychrophilic bacteria compared to that of marinating without phosphate. Phosphate pretreatment could not improve the physical quality of Tom-Yum marinated spent hen muscle and affected the antimicrobial property of Tom-Yum marinade, resulting in a reduction of shelf-life of the marinated muscle from 30 days to 20 days. Copyright (c) 2010 Society of Chemical Industry.

  7. SAFARI 2000 TOMS Tropospheric Ozone Data, Southern Africa Subset, Dry Season 2000

    Data.gov (United States)

    National Aeronautics and Space Administration — Tropical Tropospheric Ozone (TTO) data from Earth Probe (EP) Total Ozone Mapping Spectrometer (TOMS) for the period of August 8-September 29, 2000 were processed and...

  8. Tomé, futuro turístico y renacer industrial

    Directory of Open Access Journals (Sweden)

    Carol Andaluz Sandoval

    2003-01-01

    Full Text Available La ciudad de Tomé, ubicada en la ribera N.E. de la bahía de Talcahuano, distante a sólo 32 kilómetros al norte del Gran Concepción, se ha desarrollado económica y territorialmente por los diferentes aconteceres que le ha correspondido presenciar durante la historia. Es así como encontramos vestigios de la grandeza de su apogeo pesquero, portuario, molinero, vitivinícola y textil, tanto en el ordenamiento de su trama urbana como en obras arquitectónicas que muestran un claro reflejo de las inmigraciones extranjeras que se vieron atraídas por esta próspera ciudad, que nació como caleta de pescadores y se transformó en un centro industrial de gran importancia nacional. Tal fue su significancia dentro de las zonas costeras del país que en el año 1858, el Congreso Nacional declaró a Tomé Puerto Mayor, lo que se tradujo en un aumento importante de la población, la industria y las actividades que esto conllevaba.

  9. Tropospheric Ozone Pollution from Space: New Views from the TOMS (Total Ozone Mapping Spectrometer) Instrument

    Science.gov (United States)

    Thompson, Anne M.; Hudson, Robert D.; Frolov, Alexander D.; Witte, Jacquelyn C.; Kucsera, Tom L.; Einaudi, Franco (Technical Monitor)

    2000-01-01

    New products from the TOMS (Total Ozone Mapping Spectrometer) >satellite instrument can resolve pollution events in tropical and mid-latitudes, Over the past several years, we have developed tropospheric ozone data sets by two methods. The modified-residual technique [Hudson and Thompson, 1998; Thompson and Hudson, 1999] uses v. 7 TOMS total ozone and is applicable to tropical regimes in which the wave-one pattern in total ozone is observed. The TOMSdirect method [Hudson et at., 2000] represents a new algorithm that uses TOMS radiances to extract tropospheric ozone in regions of constant stratospheric ozone and tropospheric ozone displaying high mixing ratios and variability characteristic of pollution, Absorbing aerosols (dust and smoke; Herman et at., 1997 Hsu et al., 1999), a standard TOMS product, provide transport and/or source marker information to interpret tropospheric ozone. For the Nimbus 7/TOMS observing period (1979-1992), modified-residual TTO (tropical tropospheric ozone) appears as two maps/month at I-degree latitude 2-degree longitude resolution at a homepage and digital data are available (20S to 20N) by ftp at http://metosrv2. umd.edu/tropo/ 14y_data.d. Preliminary modified-residual TTO data from the operational Earth-Probe/TOMS (1996- present) are posted in near-real-time at the same website. Analyses with the new tropospheric ozone and aerosol data are illustrated by the following (I)Signals in tropical tropospheric ozone column and smoke amount during ENSO (El Nino-Southern Oscillation) events, e.g. 1982-1983 and the intense ENSO induced biomass fires of 1997-1998 over the Indonesian region [Thompson et a[, 2000a, Thompson and Hudson, 1999]. (2) Trends in tropospheric ozone and smoke aerosols in various tropical regions (Atlantic, Pacific, Africa, Brazil). No significant trends were found for ozone from1980-1990 [Thompson and Hudson, 19991 although smoke aerosols increased during the period [Hsu et al.,1999]. (3) Temporal and spatial offsets

  10. Staging Henry Fielding: The Author-Narrator in Tom Jones On Screen

    Directory of Open Access Journals (Sweden)

    Eli Løfaldli

    2017-06-01

    Full Text Available As recent adaptation theory has shown, classic-novel adaptation typically sets issues connected to authorship and literal and figurative ownership into play. This key feature of such adaptations is also central to the screen versions of Henry Fielding’s Tom Jones (1749. In much of Fielding’s fiction, the narrator, typically understood as an embodiment of Fielding himself, is a particularly prominent presence. The author-narrator in Tom Jones is no exception: not only is his presence strongly felt throughout the novel, but through a variety of means, ‘The History of Tom Jones, A Foundling’ is also distinctly marked as being under his control and ownership. The two adaptations of Fielding’s novel, a 1963 film and a 1997 television series, both retain the figure of the author-narrator, but differ greatly in their handling of this device and its consequent thematic ramifications. Although the 1963 film de-emphasises Henry Fielding’s status as proprietor of the story, the author-narrator as represented in the film’s voiceover commentary is a figure of authority and authorial control. In contrast, the 1997 adaptation emphasises Fielding’s ownership of the narrative and even includes the author-narrator as a character in the series, but this ownership is undermined by the irreverent treatment to which he is consistently subjected. The representations of Henry Fielding in the form of the author-narrator in both adaptations are not only indicative of shifting conceptions of authorship, but also of the important interplay between authorship, ownership and adaptation more generally.

  11. How Tom Moon's research highlighted the question of glucose tolerance in carnivorous fish.

    Science.gov (United States)

    Polakof, S; Panserat, S

    2016-09-01

    Fifteen years ago, Tom Moon wrote a review on this journal in order to propose some explanations to the exacerbated glycaemic response after a glucose load or a carbohydrate meal intake observed in fish, the so-called intolerance to glucose. Before, but in most of cases after this paper, several laboratories worldwide started to make important efforts in order to better understand this strange phenotype observed in fish and that so far seemed to belong to diabetic humans only. Tom had been worked on fish metabolism for at least 30years when he proposed that mini-review and the paths opened by him in 2001 were followed by tens of fish researchers, making this paper a breaking point on the field. Fifteen years later, we propose not only to have a look to the answers given to the questions rose in that paper, but also to summarize how his career over all these years impacted the domain of glucose metabolism in fish. In the review, we will show how Tom Moon analysed at different levels (from genes up to the whole organism), using distinct experimental tools (cells, hormone or glucose injection, pumps, drugs) the questions of glucose metabolism, tolerance and nutrition in fish species. Copyright © 2015 Elsevier Inc. All rights reserved.

  12. Delice(Olea europea var. oleaster L.) ile zeytin (Olea europea var.sativa) arasında anatomik ve palinojik ayrıcalıklar (The Anatomic And Palynological Differences Between Olea europea var. oleaster L. AND Olea europea var.sativa)

    OpenAIRE

    Kaya, Zafer

    1991-01-01

    Delice(Olea europea var. oleaster L.) ile zeytin (Olea europea var.sativa) arasında anatomik ve palinojik ayrıcalıklar (The Anatomic And Palynological Differences Between Olea europea var. oleaster L. AND Olea europea var.sativa)

  13. Occurrence of ozone anomalies over cloudy areas in TOMS version-7 level-2 data

    Directory of Open Access Journals (Sweden)

    X. Liu

    2003-01-01

    Full Text Available This study investigates anomalous ozone distributions over cloudy areas in Nimbus-7 (N7 and Earth-Probe (EP TOMS version-7 data and analyzes the causes for ozone anomaly formation. A 5°-longitude by 5°-latitude region is defined to contain a Positive Ozone Anomaly (POA or Negative Ozone Anomaly (NOA if the correlation coefficient between total ozone and reflectivity is > 0.5 or -0.5. The average fractions of ozone anomalies among all cloud fields are 31.8 ± 7.7% and 35.8 ± 7.7% in the N7 and EP TOMS data, respectively. Some ozone anomalies are caused by ozone retrieval errors, and others are caused by actual geophysical phenomena. Large cloud-height errors are found in the TOMS version-7 algorithm in comparison to the Temperature Humidity Infrared Radiometer (THIR cloud data. On average, cloud-top pressures are overestimated by ~200 hPa (THIR cloud-top pressure 200 hPa for high-altitude clouds and underestimated by ~150 hPa for low-altitude clouds (THIR cloud-top pressure > 750 hPa. Most tropical NOAs result from negative errors induced by large cloud-height errors, and most tropical POAs are caused by positive errors due to intra-cloud ozone absorption enhancement. However, positive and negative errors offset each other, reducing the ozone anomaly occurrence in TOMS data. Large ozone/reflectivity slopes for mid-latitude POAs show seasonal variation consistent with total ozone fluctuation, indicating that they result mainly from synoptic and planetary wave disturbances. POAs with an occurrence fraction of 30--60% occur in regions of marine stratocumulus off the west coast of South Africa and off the west coast of South America. Both fractions and ozone/reflectivity slopes of these POAs show seasonal variations consistent with that in the tropospheric ozone. About half the ozone/reflectivity slope can be explained by ozone retrieval errors over clear and cloudy areas. The remaining slope may result from there being more ozone production

  14. São Tomé and Príncipe - Business Environment and Tax Reform

    Data.gov (United States)

    Millennium Challenge Corporation — This report is a summative evaluation of the Millennium Challenge Corporation's (MCC) Threshold Country Program (TCP) for São Tomé and Príncipe. The program was...

  15. evaluation of the nutritional quality of “tom brown” weaning diet

    African Journals Online (AJOL)

    Admin

    nutritional quality of “Tom Brown” was evaluated from its total nitrogen and protein ... were significantly higher (P<0.05) than those for rats on reference diet; while protein .... Drug House (BDH) Chemical Ltd, Pole, England, and .... reproduction, protection and regulation of various body .... Official Methods of Analysis. 15th.

  16. Limited Evaluation of Image Quality Produced by a Portable Head CT Scanner (CereTom) in a Neurosurgery Centre

    Science.gov (United States)

    Abdullah, Ariz Chong; Adnan, Johari Siregar; Rahman, Noor Azman A.; Palur, Ravikant

    2017-01-01

    Introduction Computed tomography (CT) is the preferred diagnostic toolkit for head and brain imaging of head injury. A recent development is the invention of a portable CT scanner that can be beneficial from a clinical point of view. Aim To compare the quality of CT brain images produced by a fixed CT scanner and a portable CT scanner (CereTom). Methods This work was a single-centre retrospective study of CT brain images from 112 neurosurgical patients. Hounsfield units (HUs) of the images from CereTom were measured for air, water and bone. Three assessors independently evaluated the images from the fixed CT scanner and CereTom. Streak artefacts, visualisation of lesions and grey–white matter differentiation were evaluated at three different levels (centrum semiovale, basal ganglia and middle cerebellar peduncles). Each evaluation was scored 1 (poor), 2 (average) or 3 (good) and summed up to form an ordinal reading of 3 to 9. Results HUs for air, water and bone from CereTom were within the recommended value by the American College of Radiology (ACR). Streak artefact evaluation scores for the fixed CT scanner was 8.54 versus 7.46 (Z = −5.67) for CereTom at the centrum semiovale, 8.38 (SD = 1.12) versus 7.32 (SD = 1.63) at the basal ganglia and 8.21 (SD = 1.30) versus 6.97 (SD = 2.77) at the middle cerebellar peduncles. Grey–white matter differentiation showed scores of 8.27 (SD = 1.04) versus 7.21 (SD = 1.41) at the centrum semiovale, 8.26 (SD = 1.07) versus 7.00 (SD = 1.47) at the basal ganglia and 8.38 (SD = 1.11) versus 6.74 (SD = 1.55) at the middle cerebellar peduncles. Visualisation of lesions showed scores of 8.86 versus 8.21 (Z = −4.24) at the centrum semiovale, 8.93 versus 8.18 (Z = −5.32) at the basal ganglia and 8.79 versus 8.06 (Z = −4.93) at the middle cerebellar peduncles. All results were significant with P-value < 0.01. Conclusions Results of the study showed a significant difference in image quality produced by the fixed CT scanner and

  17. Interpretation of TOMS Observations of Tropical Tropospheric Ozone with a Global Model and In Situ Observations

    Science.gov (United States)

    Martin, Randall V.; Jacob, Daniel J.; Logan, Jennifer A.; Bey, Isabelle; Yantosca, Robert M.; Staudt, Amanda C.; Fiore, Arlene M.; Duncan, Bryan N.; Liu, Hongyu; Ginoux, Paul

    2004-01-01

    We interpret the distribution of tropical tropospheric ozone columns (TTOCs) from the Total Ozone Mapping Spectrometer (TOMS) by using a global three-dimensional model of tropospheric chemistry (GEOS-CHEM) and additional information from in situ observations. The GEOS-CHEM TTOCs capture 44% of the variance of monthly mean TOMS TTOCs from the convective cloud differential method (CCD) with no global bias. Major discrepancies are found over northern Africa and south Asia where the TOMS TTOCs do not capture the seasonal enhancements from biomass burning found in the model and in aircraft observations. A characteristic feature of these northern topical enhancements, in contrast to southern tropical enhancements, is that they are driven by the lower troposphere where the sensitivity of TOMS is poor due to Rayleigh scattering. We develop an efficiency correction to the TOMS retrieval algorithm that accounts for the variability of ozone in the lower troposphere. This efficiency correction increases TTOC's over biomass burning regions by 3-5 Dobson units (DU) and decreases them by 2-5 DU over oceanic regions, improving the agreement between CCD TTOCs and in situ observations. Applying the correction to CCD TTOCs reduces by approximately DU the magnitude of the "tropical Atlantic paradox" [Thompson et al, 2000], i.e. the presence of a TTOC enhancement over the southern tropical Atlantic during the northern African biomass burning season in December-February. We reproduce the remainder of the paradox in the model and explain it by the combination of upper tropospheric ozone production from lightning NOx, peristent subsidence over the southern tropical Atlantic as part of the Walker circulation, and cross-equatorial transport of upper tropospheric ozone from northern midlatitudes in the African "westerly duct." These processes in the model can also account for the observed 13-17 DU persistent wave-1 pattern in TTOCs with a maximum above the tropical Atlantic and a minimum

  18. TOMS as a monitor of the ultraviolet radiation environment: applications to photobiology

    International Nuclear Information System (INIS)

    Frederick, J.E.

    1987-01-01

    The flux of biologically relevant ultraviolet radiation that reaches the surface of the Earth varies with the ozone amount, surface reflectivity, and cloudcover. The Total Ozone Mapping Spectrometer (TOMS) provides information relevant to all three items. A recent application of satellite-based ozone measurements has been to develop climatologies of the biologically significant UV-B radiation reaching the Earth's surface. A growing body of research suggests that UV-B radiation tends to suppress the immune system of laboratory mice. At tropical latitudes, it is likely that parasitical diseases develop most readily in people who have experienced immune system suppression from UV-B exposure. The computed distribution of surface radiation combined with information on disease incidence may clarify the role of UV-B as a suppressor of the human immune system. TOMS used in conjunction with radiative transfer calculations can provide information of relevance in photobiology

  19. Enhancing Nanos expression via the bacterial TomO protein is a conserved strategy used by the symbiont Wolbachia to fuel germ stem cell maintenance in infected Drosophila females.

    Science.gov (United States)

    Ote, Manabu; Yamamoto, Daisuke

    2018-04-27

    The toxic manipulator of oogenesis (TomO) protein has been identified in the wMel strain of Wolbachia that symbioses with the vinegar fly Drosophila melanogaster, as a protein that affects host reproduction. TomO protects germ stem cells (GSCs) from degeneration, which otherwise occurs in ovaries of host females that are mutant for the gene Sex-lethal (Sxl). We isolated the TomO homologs from wPip, a Wolbachia strain from the mosquito Culex quinquefasciatus. One of the homologs, TomO w Pip 1, exerted the GSC rescue activity in fly Sxl mutants when lacking its hydrophobic stretches. The GSC-rescuing action of the TomO w Pip 1 variant was ascribable to its abilities to associate with Nanos (nos) mRNA and to enhance Nos protein expression. The analysis of structure-activity relationships with TomO homologs and TomO deletion variants revealed distinct modules in the protein that are each dedicated to different functions, i.e., subcellular localization, nos mRNA binding or Nos expression enhancement. We propose that modular reshuffling is the basis for structural and functional diversification of TomO protein members. © 2018 Wiley Periodicals, Inc.

  20. Tom Brown to direct Office for Student Life at Virginia Tech

    OpenAIRE

    Cox, Clara B.

    2004-01-01

    James Thomas "Tom" Brown of Blacksburg, Va., former interim director of the Office for Student Life and Advocacy, has been named director of the office, which has been renamed the Office for Student Life. The newly named office is responsible for multicultural programs, student advocacy, orientation, parent programs, and response to student emergencies.

  1. The Decade Ahead: Inquire, Innovate, Impact. Tomás Rivera Lecture Series

    Science.gov (United States)

    Pacheco, Manuel T.

    2015-01-01

    In the 2015 Tomás Rivera lecture, Manuel T. Pacheco, President Emeritus of the University of Missouri System and the University of Arizona, discusses the importance of representing the Hispanic American population proportionately among college students, faculty, staff, and administration in higher education.

  2. ABD’deki Kadın Okul Bölgesi Müdürlerinin Yaşadığı Cinsiyet Ayrımcılığına Dayalı Sorunlar, Üstesinden Gelme Yolları ve Öneriler

    OpenAIRE

    Babaoğlan, Emine

    2017-01-01

    Araştırmanın amacı, ABD’deki okul bölgesi müdürlerinin cinsiyet ayrımcılığına dayalı yaşadıkları sorunları, nedenlerini, üstesinden gelme yollarını ve önerilerini belirlemektir. Araştırma 15 kadın okul bölgesi müdürünün görüşlerine dayanan nitel araştırmadır. Verilerin analizinde içerik analizi kullanılmıştır. Araştırmada, kadın müdürlerin çoğunluğunun cinsiyet ayrımcılığı yaşadığı belirlenmiştir. Yaşanan sorunlar erkeklerin müdür olarak tercih edilirken kadınların edilmemesi; kadınların yöne...

  3. Technical Note: Adjoint formulation of the TOMCAT atmospheric transport scheme in the Eulerian backtracking framework (RETRO-TOM)

    Science.gov (United States)

    Haines, P. E.; Esler, J. G.; Carver, G. D.

    2014-06-01

    A new methodology for the formulation of an adjoint to the transport component of the chemistry transport model TOMCAT is described and implemented in a new model, RETRO-TOM. The Eulerian backtracking method is used, allowing the forward advection scheme (Prather's second-order moments) to be efficiently exploited in the backward adjoint calculations. Prather's scheme is shown to be time symmetric, suggesting the possibility of high accuracy. To attain this accuracy, however, it is necessary to make a careful treatment of the "density inconsistency" problem inherent to offline transport models. The results are verified using a series of test experiments. These demonstrate the high accuracy of RETRO-TOM when compared with direct forward sensitivity calculations, at least for problems in which flux limiters in the advection scheme are not required. RETRO-TOM therefore combines the flexibility and stability of a "finite difference of adjoint" formulation with the accuracy of an "adjoint of finite difference" formulation.

  4. Can REDD+ help the conservation of restricted-range island species? Insights from the endemism hotspot of São Tomé

    DEFF Research Database (Denmark)

    de Lima, Ricardo Faustino; Olmos, Fábio; Dallimer, Martin

    2013-01-01

    , using São Tomé Island (Democratic Republic of São Tomé and Príncipe) as a case study. We quantified the abundance of bird and tree species, and calculated the aboveground carbon stocks across a gradient of land-use intensity. We found a strong spatial congruence between carbon and the presence...

  5. Metabolite profile of the tomato dwarf cultivar Micro-Tom and comparative response to saline and nutritional stresses with regard to a commercial cultivar.

    Science.gov (United States)

    Flores, Pilar; Hernández, Virginia; Hellín, Pilar; Fenoll, Jose; Cava, Juana; Mestre, Teresa; Martínez, Vicente

    2016-03-30

    The dwarf tomato variety Micro-Tom has been used as a plant model for studies of plant development. However, its response to environmental and agricultural factors has not been well studied. This work studies the phytochemical content of Micro-Tom tomato and its comparative response to saline and nutritional (N, K and Ca) stresses with regard to a commercial variety. The chromatographic profiles of Micro-Tom were similar to those of the commercial variety and the only differences appear to be the concentration of the components. In Micro-Tom, the concentrations of sugars and organic acids increased by salinity in a lesser extent than in Optima. Moreover, contrary to that observed in the commercial variety, phenolic compounds and vitamin C did not increase by salinity in the dwarf variety. However, both varieties increased similarly the concentrations of carotenoids under saline conditions. Finally, fruit yield and most primary and secondary metabolite concentrations in Micro-Tom were not affected by N, K or Ca limitation. The mutations leading to the dwarf phenotype did not greatly alter the metabolite profiles but studies using Micro-Tom as a plant model should consider the lower capacity for sugars and organic acids under saline conditions and the greater tolerance to nutrient limitation of the dwarf variety. © 2015 Society of Chemical Industry.

  6. TOM1L Is Involved in a Novel Signaling Pathway Important for the IL-2 Production in Jurkat T Cells Stimulated by CD3/CD28 CoLigation

    Directory of Open Access Journals (Sweden)

    Ahmed Elmarghani

    2009-01-01

    Full Text Available TOM1L (target of Myb-1 Like was identified as a binding partner for the full length and catalytically-active Lck in a yeast 2-hybrid screening assay. Here we show that in Jurkat T cells stimulated by CD3/CD28 coligation where the expression of TOM1L is reduced by lenti virus mediated-siRNA results in a dramatically lower IL-2 production. The production of IL-2 in siRNA treated cells stimulated with PMA/ionomycin was not affected indicating an involvement of TOM1L in a pathway proximal of TCR and CD28. The coexpression of Fyn with TOM1L increased the level of the phosphorylated form of Fyn indicating that TOM1L has the ability to activate Fyn. The ability of TOM1L to activate Fyn was further shown in a kinase assay using angiotensin II as a substrate. By confocal microscopy, we show that the expression of TOM1L in non-treated HeLa and SK-N-SH cells colocalizes with the mitochondrial membrane but not with lysosomal compartments or the trans-Golgi network. Furthermore, we show that the over-expression of TOM1L in Jurkat cells causes an increase of the STAT3 expression . Based on our results, we here propose that TOM1L is involved in a novel signaling pathway that is important for the IL-2 production in T cells.

  7. Tomás Carrasquilla

    Directory of Open Access Journals (Sweden)

    Amalia Franco Castaño

    2014-01-01

    Full Text Available El reconocimiento de la obra del escritor antioqueño Tomás Carrasquilla, como una obra asociada al realismo y a los principios de interpretación de las relaciones sociales que esta propuesta implica permite que, desde la composición, el esquema de los personajes y los usos del lenguaje, pueda leerse una postura crítica que se distan - cia de las normas estéticas vigentes, para mostrar las contradicciones y los desacuerdos con los proyectos políticos e ideológicos que las respaldaban. Es así como Carrasquilla concreta en una novela como La Marquesa de Yolombó la expresión de una toma de posición que se respalda en la composición de un personaje femenino desde el cual expone no solo las implicaciones de una época de la sociedad colombiana sino, además, las posibilidades de comunicación con un presente que para el escritor amerita ser cuestionado y revelado desde la descomposición de la vida social y las contradicciones de los proyectos de liberación en Colombia.

  8. Ratio superior, ratio inferior y el agustinismo de Tomás de Aquino

    Directory of Open Access Journals (Sweden)

    Moya Cañas, Patricia

    2013-12-01

    Full Text Available This article discusses Aquinas’ reception of the Augustinian distinction between ratio inferior and superior. Though not a central aspect of Aquinas’ thought, it is a signifi cant pointer to the presence of Augustinian patterns of thought in a non-theological part of his work. After a general survey of the presence of this distinction in the opera omnia of Aquinas, his use of this topic in some specific instances is discussed: the distinction between contemplative and active life, the division of human faculties, and the moral problem of peevish delight.El artículo discute la recepción que hace Tomás de Aquino de la distinción agustiniana entre razón superior e inferior. Si bien no se trata de uno de los tópicos centrales de la doctrina tomasiana, es un elemento significativo a la hora de considerar dentro de la obra de Tomás la presencia de patrones agustinianos de pensamiento que no sean primordialmente teológicos. Tras discutir de modo general la presencia de esta distinción en la obra del aquinate, y los estudios previos sobre este binomio, se procede a discutir su uso por parte de Tomás de Aquino ante tres problemas específicos: la distinción entre géneros de vida, la división de las facultades humanas, y el problema moral de la delectación morosa.

  9. Derivation of Tropospheric Ozone Climatology and Trends from TOMS Data

    Science.gov (United States)

    Newchurch, Michael J.; McPeters, Rich; Logan, Jennifer; Kim, Jae-Hwan

    2002-01-01

    This research addresses the following three objectives: (1) Derive tropospheric ozone columns from the TOMS instruments by computing the difference between total-ozone columns over cloudy areas and over clear areas in the tropics; (2) Compute secular trends in Nimbus-7 derived tropospheric Ozone column amounts and associated potential trends in the decadal-scale tropical cloud climatology; (3) Explain the occurrence of anomalously high ozone retrievals over high ice clouds.

  10. Çalışanların İş Güvencesizliğinin İşten Ayrılma Niyetleri Üzerindeki Etkisi: Alanya Bölgesindeki Beş Yıldızlı Otellerde Bir Araştırma

    OpenAIRE

    KARACAOĞLU, Korhan

    2018-01-01

    İş güvencesizliği, mevcut işin sürekliliğine engel olacak her türlü yasal veya yasal olmayan örgütsel değişimler sonucunda ortaya çıkan, işgörende, belirsizlik düşüncesine dayalı olarak işini kaybetme kaygısı doğuran durumlardır. Alan yazında iş güvencesizliğinin sonuçlarından biri olan işten ayrılma niyeti ise bir çalışanın yakın bir zamanda işine son verme isteğiyle ilgili düşüncesi olarak tanımlanmaktadır. Bu çalışmada iş güvencesizliği ile işten ayrılma niyeti arasındaki etkileşim Alanya ...

  11. Music and subversion in Tom Stoppard's rock 'n'roll

    OpenAIRE

    Matos, Susana Isabel Mendes de

    2013-01-01

    This dissertation aims at analysing music as a form of subversion in Tom Stoppard’s play Rock ‘N’ Roll. After a short summary of Stoppard’s career, the bands and songs chosen by him are analysed from the perspective of subversion against censorship and totalitarian regimes, relating them to the plot. The dissertation also focuses on the specific case of the Czech band the Plastic People of the Universe and its importance to the history of Czechoslovakia between 1968 and 1990. O presente tr...

  12. Reciclando a Tropicália: Tom Zé e o lixo lógico

    Directory of Open Access Journals (Sweden)

    Paula Oliveira Campos Augusto

    2015-06-01

    Full Text Available http://dx.doi.org/10.5007/2176-8552.2016n20p111 Este artigo tem como objetivo apresentar e analisar a tese de Tom Zé sobre a Tropicália, presente em seu disco Tropicália lixo lógico, lançado em 2012. Primeiramente, destacam-se duas características importantes da música popular brasileira, que ajudam a entender a possibilidade de um disco--tese: além de ser definida como um “campo dialogal” (1, a música popular brasileira é dotada de uma “malha de permeabilidades”, pelo modo como a alta cultura se cruza com produções populares, tendo como resultado a “leveza” (2. Em seu álbum, Tom Zé não apenas assume o protagonismo da interpretação da Tropicália, mas, também, desloca a antropofagia do centro interpretativo dessa manifestação artística e cultural brasileira. Nesse sentido, o disco é compreendido, levando-se em conta tanto seus aspectos físicos quanto simbólicos, a partir do que Walter Moser denomina de reciclagem cultural, uma vez que Tom Zé processa a inclusão de “restos” e “dejetos” no espaço cultural e artístico. Ademais, com a reciclagem do lixo lógico, o espaço hegemônico incorpora materiais culturais de outras procedências, colocando-os em diálogo.

  13. Collateral Damage: Veterans and Domestic Violence in Mari Sandoz's "The Tom-Walker"

    Science.gov (United States)

    Bahr, Kathy

    2010-01-01

    "The Tom-Walker" combines the best of Sandoz's realism with her worst attempts at moralizing. Unable to divine exactly what political configuration right-wing post-World War II sentiments might take, Sandoz nevertheless feared a fascist uprising in this country. Perhaps because these concerns dominated her thoughts at the time, she allowed her…

  14. Molecular biology and riddle of cancer: the ‘Tom & Jerry’ show

    Directory of Open Access Journals (Sweden)

    Md. Al Mamun

    2011-11-01

    Full Text Available From the conventional Bird’s eye, cancer initiation and metastasis are generally intended to be understood beneath the light of classical clonal genetic, epigenetic and cancer stem cell model. But inspite decades of investigation, molecular biology has shown hard success to give Eagle’s eye in unraveling the riddle of cancer. And it seems, tiring Tom runs in vague behind naughty Jerry.

  15. SIM PlanetQuest: The TOM-3 (Thermo-Optical-Mechanical) Siderostat Mirror Test

    Science.gov (United States)

    Phillips, Charles J.

    2006-01-01

    This slide presentation reviews the Space Interferometry Mission (SIM) PlanetQuest mission. It describes the mission, shows diagrams of the instrument, the collector bays, the Siderostat mirrors, the COL bay thermal environment, the TOM-3 replicating COL Bay Environment, the thermal hardware for the SID heater control, and the results of the test are shown

  16. Resolução e apreensão de princípios em Tomás de Aquino [Resolution and apprehension of principles in Aquinas

    Directory of Open Access Journals (Sweden)

    Matheus Pazos

    2016-06-01

    Full Text Available O escopo do presente artigo consiste em investigar a função da resolução na apreensão de princípios em Tomás de Aquino. Para tanto, examino o sentido da resolução do ente efetuada por Tomás em De veritate, q. 1, a. 1. Com o intuito de elucidar esse extrato textual, tenho por objetivo explicitar como Tomás associa o emprego da resolução, entendida como método próprio da razão humana, com a apreensão intelectual do ente que, de acordo com Tomás, é o princípio geral sem o qual todo conhecimento humano encontrar-se-ia desprovido de fundamentação.

  17. ‘My country’s heart is in the market place’: Tom Stannage interviewed by Peter Read

    Directory of Open Access Journals (Sweden)

    Tiffany Shellam

    2013-12-01

    Full Text Available Tom Stannage was one among many historians in the 1970s uncovering histories of Australia which were to challenge national narratives and community memories. In 1971, Tom returned to Western Australia after writing his PhD in Cambridge with the passion to write urban history and an understanding that in order to do so, he needed an emotional engagement with place. What he had yet to realize was the power of community memories in Western Australia to shape and preserve ideas about their place. As part of his research on the history of Perth, Tom saw how the written histories of Western Australia had been shaped by community mythologies – in particular that of the rural pioneer. He identified the consensus or ‘gentry tradition’ in Western Australian writing. In teasing out histories of conflict, he showed how the gentry tradition of rural pioneer histories silenced those of race and gender relations, convictism and poverty which were found in both rural and urban areas. His versions of history began to unsettle parts of the Perth community who found the ‘pioneer myth’ framed their consensus world-view and whose families were themselves the living links to these ‘pioneers’.

  18. Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase Parkin.

    Science.gov (United States)

    Lazarou, Michael; Jin, Seok Min; Kane, Lesley A; Youle, Richard J

    2012-02-14

    Mutations in the mitochondrial kinase PINK1 and the cytosolic E3 ligase Parkin can cause Parkinson's disease. Damaged mitochondria accumulate PINK1 on the outer membrane where, dependent on kinase activity, it recruits and activates Parkin to induce mitophagy, potentially maintaining organelle fidelity. How PINK1 recruits Parkin is unknown. We show that endogenous PINK1 forms a 700 kDa complex with the translocase of the outer membrane (TOM) selectively on depolarized mitochondria whereas PINK1 ectopically targeted to the outer membrane retains association with TOM on polarized mitochondria. Inducibly targeting PINK1 to peroxisomes or lysosomes, which lack a TOM complex, recruits Parkin and activates ubiquitin ligase activity on the respective organelles. Once there, Parkin induces organelle selective autophagy of peroxisomes but not lysosomes. We propose that the association of PINK1 with the TOM complex allows rapid reimport of PINK1 to rescue repolarized mitochondria from mitophagy, and discount mitochondrial-specific factors for Parkin translocation and activation. Copyright © 2012 Elsevier Inc. All rights reserved.

  19. Hauntology of Responsibility: Tom Stoppard’s Darkside

    Directory of Open Access Journals (Sweden)

    Tymon Adamczewski

    2017-10-01

    Full Text Available The article centres on the notion of responsibility in Tom Stoppard’s Darkside (2013. While Pink Floyd’s original album, which inspired the playwright, thematises its connection to ethics in a spectral and hauntological manner, through the use of field recording sound snippets interwoven in the music, the radio play explores the notion of responsibility through what is called “thought experiments.” The article identifies the subversive function of these narrative examples and, following Emanuel Levinas’ suggestions concerning the instability of the link between the philosophical discourse and that of examples, shows the latter’s insolent and disruptive nature. The notion of responsibility is further linked to its discussion by Jacques Derrida in his Gift of Death (1995 which consequently makes it possible to view the relation between responsibility and responding from a subversive, hauntological and undecidable perspective.

  20. Hombres. Don Tomás Rueda Vargas

    Directory of Open Access Journals (Sweden)

    Boletin Cultural y Bibliográfico Banco de la República

    1958-07-01

    Full Text Available Quince años hizo el 25 de julio que desapareció de entre nosotros don Tomás Rueda Vargas. Su nombre, ejemplar por muchos conceptos, viene siempre nimbado de las virtudes cardinales que conformaron su tarea y su vida. Escritor nato,  sabía manejar el idioma con singular pericia sin caer en  rebuscamientos  ni  en  gongorismos. Su  pensamiento era diáfano por  lo cual no se  perdía en  el laberinto de  las palabras.   Apenas éstas eran  el dócil  instrumento para su dialéctica, para ese  generoso razo­  namiento intelectual que constituía el  Alfa  y el Omega   de  su diario batallar.

  1. Lope y Boccalini: Tres sonetos de Tomé de Burguillos

    Directory of Open Access Journals (Sweden)

    Arellano, Ignacio

    2012-12-01

    Full Text Available The article analyzes three sonnets of Lope against Traiano Boccalini included in the Rhymes of Tomé de Burguillos, showing the need to compare the Lope´s text with the italian original version of Ragguagli di Parnaso, not with spanish translation of Perez de Sousa, because in this translation are deleted essential passages to understand the game of wit of Lope. These three sonnets are a good example of the complexity of this exercise of conceptism in Lope, whose poetry can not be described as plain, simple and clear: it is a difficult poetry full of games, intertextual allusions and references that should be clarified applying the type of appropiate reading.Se analizan tres sonetos de Lope contra el italiano Traiano Boccalini, incluidos en las Rimas de Tomé de Burguillos, mostrando la necesidad de comparar el texto de Lope con el de los Ragguagli di Parnaso, en su versión original italiana, y no en la traducción de Perez de Sousa, que elimina pasajes necesarios para entender los juegos de Lope. Estos tres sonetos son buena muestra de la complejidad que puede tener este ejercicio de agudeza de Lope, cuya poesía no se puede calificar sin más de llana, sencilla o clara: es una poesía conceptista llena de juegos, alusiones y referencias intertextuales que deben ser aclaradas si se quiere aplicar a estos poemas el tipo de lectura que exigen.

  2. The Effect of New Ozone Cross Sections Applied to SBUV and TOMS Retrievals

    Science.gov (United States)

    McPeters, Richard D.; Labow, Gordon J.

    2010-01-01

    The ozone cross sections as measured by Bass and Paur have been used for processing of SBUV and TOMS data since 1986. While these cross sections were a big improvement over those previously available, there were known minor problems with accuracy for wavelengths longward of 330 nm and with the temperature dependance. Today's requirements to separate stratospheric ozone from tropospheric ozone and for the derivation of minor species such as BrO and N02 place stringent new requirements on the accuracy needed. The ozone cross section measurements of Brion, Daumont, and Malicet (BDM) are being considered for use in UV-based ozone retrievals. They have much better resolution, an extended wavelength range, and a more consistent temperature dependance. Tests show that BDM retrievals exhibit lower retrieval residuals in the satellite data; i.e., they explain our measured atmospheric radiances more accurately. Total column ozone retrieved by the TOMS instruments is about 1.5% higher than before. Ozone profiles retrieved from SBUV using the new cross sections are lower in the upper stratosphere and higher in the lower stratosphere and troposphere.

  3. Spatial Politics in Tom Stoppard’s Rosencrantz and Guildenstern Are Dead

    OpenAIRE

    Elham Kazemi; Mohsen Hanif

    2017-01-01

    http://dx.doi.org/10.5007/2175-8026.2017v70n1p287 This article examines the notion of spatial politics in Tom Stoppard’s Rosencrantz and Guildenstern Are Dead. The two courtiers enter the politically convulsive world of Hamlet, where no legitimate power structure takes hold of the state. Their regularized political rationality ceases to apply to the world; reality violates the empirical knowledge — emplacements, geographical and spiritual directions, and generally identity — of Rosencrant...

  4. Toward a Latino Attainment Agenda: Shaping Our Own Destiny. Tomás Rivera Lecture Series

    Science.gov (United States)

    Cigarroa, Francisco G.

    2013-01-01

    In the 2013 Tomás Rivera lecture, Francisco Cigarroa, chancellor of the University of Texas system, discusses how a major shift in the demographics of the United States is having a profound effect on K-12 and higher education.

  5. Gastronomía y turismo en Argentina. Polo gastronómico Tomás Jofré

    Directory of Open Access Journals (Sweden)

    Schlüter, Regina G.

    2008-04-01

    Full Text Available Culinary Tourism in Argentina. The Case of Tomás Jofré. The importance of culinary tourism is growing steadily both in developing and industrialized societies. Argentina has a long tradition regarding this kind of tourism, mainly wine tourism, reflected in the National Wine Festival held since 1936 en the province of Mendoza. By the end of the 20th century culinary tourism was brought into the national tourism plan and it was the start for the private sector to develop own initiatives in order to develop small towns into culinary attractions for visitors. This article presents the results of a study undertaken in order to get acquainted with the visitor profile and motivations for visitors to Tomás Jofré during Sun-days.

  6. Tom Beaver, Creek Television Reporter. With Teacher's Guide. Native Americans of the Twentieth Century.

    Science.gov (United States)

    Minneapolis Public Schools, MN.

    A biography for elementary school students presents an account of an American Indian television reporter, Tom Beaver (Creek), and includes a map of Oklahoma showing the location of Indian tribes. A teacher's guide following the biography contains information about the Creek tribe and the history of television, learning objectives and directions…

  7. Social Infrastructure to Integrate Science and Practice: the Experience of the Long Tom Watershed Council

    Directory of Open Access Journals (Sweden)

    Rebecca L. Flitcroft

    2009-12-01

    Full Text Available Ecological problem solving requires a flexible social infrastructure that can incorporate scientific insights and adapt to changing conditions. As applied to watershed management, social infrastructure includes mechanisms to design, carry out, evaluate, and modify plans for resource protection or restoration. Efforts to apply the best science will not bring anticipated results without the appropriate social infrastructure. For the Long Tom Watershed Council, social infrastructure includes a management structure, membership, vision, priorities, partners, resources, and the acquisition of scientific knowledge, as well as the communication with and education of people associated with and affected by actions to protect and restore the watershed. Key to integrating science and practice is keeping science in the loop, using data collection as an outreach tool, and the Long Tom Watershed Council's subwatershed enhancement program approach. Resulting from these methods are ecological leadership, restoration projects, and partnerships that catalyze landscape-level change.

  8. Effects of packaging materials on the aroma stability of Thai 'tom yam' seasoning powder as determined by descriptive sensory analysis and gas chromatography-mass spectrometry.

    Science.gov (United States)

    Leelaphiwat, Pattarin; Harte, Janice B; Auras, Rafael A; Ong, Peter Kc; Chonhenchob, Vanee

    2017-04-01

    Changes in the aroma characteristics of Thai 'tom yam' seasoning powder, containing lemongrass, galangal and kaffir lime leaf, as affected by different packaging materials were assessed using quantitative descriptive analysis (QDA) and gas chromatography-mass spectrometry (GC-MS). The descriptive aroma attributes for lemongrass, galangal and kaffir lime leaf powders were developed by the QDA panel. The mixed herb and spice seasoning powder was kept in glass jars closed with different packaging materials (Nylon 6, polyethylene terephthalate (PET) and polylactic acid (PLA)) stored at 38 °C (accelerated storage condition), and evaluated by the trained QDA panel during storage for 49 days. The descriptive words for Thai 'tom yam' seasoning powder developed by the trained panelists were lemongrass, vinegary and leafy for lemongrass, galangal and kaffir lime leaf dried powder, respectively. The aroma intensities significantly (P ≤ 0.05) decreased with increased storage time. However, the intensity scores for aroma attributes were not significantly (P > 0.05) different among the packaging materials studied. The major components in Thai 'tom yam' seasoning powder, quantified by GC-MS, were estragole, bicyclo[3.1.1]heptane, β-bisabolene, benzoic acid and 2-ethylhexyl salicylate. The concentrations of major aroma compounds significantly (P ≤ 0.05) decreased with storage time. Aroma stability of Thai 'tom yam' powder can be determined by descriptive sensory evaluation and GC-MS analysis. Nylon, PET and PLA exhibited similar aroma barrier properties against key aroma compounds in Thai 'tom yam'. This information can be used for prediction of aroma loss through packaging materials during storage of Thai 'tom yam'. © 2016 Society of Chemical Industry. © 2016 Society of Chemical Industry.

  9. Die soektog na 'n mitiese wêreld: Equatoria van Tom Dreyer

    OpenAIRE

    RENDERS, Luc

    2010-01-01

    Equatoria (2006) is Tom Dreyer's third novel. It is a historical novel, which is situated in 1912 in the Belgian Congo. Equatoria makes use of an age old narrative pattern, namely the quest, and combines historical and mythological sources. Dreyer loosely bases his novel on the expedition of Herbert Lang and James Chapin to the Congo from 1909 to 1915. With the historical facts Dreyer creates a fictional world with strongly mythical overtones. The hunt for the elusive okapi is the focal point...

  10. Spatial Politics in Tom Stoppard’s Rosencrantz and Guildenstern Are Dead

    OpenAIRE

    Kazemi, Elham; Hanif, Mohsen

    2017-01-01

     http://dx.doi.org/10.5007/2175-8026.2017v70n1p287This article examines the notion of spatial politics in Tom Stoppard’s Rosencrantz and Guildenstern Are Dead. The two courtiers enter the politically convulsive world of Hamlet, where no legitimate power structure takes hold of the state. Their regularized political rationality ceases to apply to the world; reality violates the empirical knowledge — emplacements, geographical and spiritual directions, and generally identity — of Rosencrantz an...

  11. Aerial Photography and Imagery, Ortho-Corrected, Polk County retained Ayres Associates to acquire digital aerial photography during the spring of 2010 suitable for the production of color orthophotography at a 12-inch ground pixel resolution (approximately 956 sq. miles). The photography was obtained du, Published in 2010, 1:2400 (1in=200ft) scale, Polk County Government.

    Data.gov (United States)

    NSGIC Local Govt | GIS Inventory — Aerial Photography and Imagery, Ortho-Corrected dataset current as of 2010. Polk County retained Ayres Associates to acquire digital aerial photography during the...

  12. O tom, tshto ushlo : [luuletused] / Aleksander Suuman ; Lühibiograafia: T. L. [Toomas Liiv

    Index Scriptorium Estoniae

    Suuman, Aleksander, 1927-2003

    1999-01-01

    Sisu: O tom, tshto ushlo ; "Gde-to dolzhno zhe bõt stshastje..." ; "Serõje lessa..." ; Zholtogolovõ ; "Teh iv serebristõh nelzja oboiti..." ; "Vzroslõje vkladtshinu pili..." ; "U nas tut, za Giperborejem..." / tlk. Svetlan Semenenko ; Odno hotshu skazat ; Los idjot / tlk. Boris Baljasnõi.Orig.: "Kusagil peab olema õnn..." ; Kullerkupud ; "Ei hõbepajust ma mööduda saand..." ; "Meil siin Hüperboreas..." ;

  13. Estimations of the Global Distribution and Time Series of UV Noontime Irradiance (305, 310, 324, 380 nm, and Erythemal) from TOMS and SeaWiFS Data

    Science.gov (United States)

    Herman, J.

    2004-01-01

    The amount of UV irradiance reaching the Earth's surface is estimated from the measured cloud reflectivity, ozone, aerosol amounts, and surface reflectivity time series from 1980 to 1992 and 1997 to 2000 to estimate changes that have occurred over a 21-year period. Recent analysis of the TOMS data shows that there has been an apparent increase in reflectivity (decrease in W) in the Southern Hemisphere that is related to a calibration error in EP-TOMS. Data from the well-calibrated SeaWiFS satellite instrument have been used to correct the EP-TOMS reflectivity and UV time series. After correction, some of the local trend features seen in the N7 time series (1980 to 1992) have been continued in the combined time series, but the overall zonal average and global trends have changed. In addition to correcting the EP-TOMS radiance calibration, the use of SeaWiFS cloud data permits estimation of UV irradiance at higher spatial resolution (1 to 4 km) than is available from TOMS (100 km) under the assumption that ozone is slowly varying over a scale of 100 km. The key results include a continuing decrease in cloud cover over Europe and North America with a corresponding increase in UV and a decrease in UV irradiance near Antarctica.

  14. Língua Gestual de São Tomé e Príncipe : retrato dos primeiros gestos

    Directory of Open Access Journals (Sweden)

    Ana Mineiro

    2016-09-01

    Full Text Available This paper aims to portray the genesis of São Tomé and Príncipe Sign Language. At the request of the Government of São Tomé and Principe (Ministry of Education, Culture and Science, Cell Special Education, the Portuguese Catholic University together with the Marquês of Valle Flôr Institute and Hospital CUF Infante Santo collaborated on a common project: to implement a Sign Language for the deaf Santomean. This project, funded by the Calouste Gulbenkian Foundation, was given the name of Without Barriers. The paper is structured in two parts: the first part, which describes, in summary, the main lines of action of the project, the participants enrolled in the project and the methodology used and the second part that analyzes the emergence of the first signs, using sometimes, comparison with other emerging languages.

  15. Secret Guilt of an Artist: The Real Inspector Hound and Tom Stoppard’s Political Voice

    Directory of Open Access Journals (Sweden)

    Kevin Drzakowski

    2015-12-01

    Full Text Available Tom Stoppard once famously proclaimed his guilt that art is unimportant. The character Moon from Stoppard’s early farce The Real Inspector Hound presents surprising evidence that Stoppard’s view of art in his early years as a playwright may have been more complex than he let on. The circumstances behind Moon’s journey into the very art he criticizes are not unlike Tom Stoppard’s foray into politically conscious drama. Moon desperately wants the thriller he is reviewing to mean more than it really does. His wish becomes a reality when a third party, Puckeridge, forcibly pulls Moon into the fantasy. Like Moon, Stoppard had a fantasy, a dream-world in which art has the power to enact social change. Stoppard was unwilling or unable to act on that desire alone, until his own Puckeridge, an artist and dissident named Victor Fainberg, compelled him to act on his dream and merge art with politics.Keywords: Stoppard, The Real Inspector Hound, Fainberg, art, politics

  16. NMR investigations of the dual targeting peptide of Thr-tRNA synthetase and its interaction with the mitochondrial Tom20 receptor in Arabidopsis thaliana.

    Science.gov (United States)

    Ye, Weihua; Spånning, Erika; Unnerståle, Sofia; Gotthold, David; Glaser, Elzbieta; Mäler, Lena

    2012-10-01

    Most mitochondrial proteins are synthesized in the cytosol as precursor proteins containing an N-terminal targeting peptide and are imported into mitochondria through the import machineries, the translocase of the outer mitochondrial membrane (TOM) and the translocase of the inner mitochondrial membrane (TIM). The N-terminal targeting peptide of precursor proteins destined for the mitochondrial matrix is recognized by the Tom20 receptor and plays an important role in the import process. Protein import is usually organelle specific, but several plant proteins are dually targeted into mitochondria and chloroplasts using an ambiguous dual targeting peptide. We present NMR studies of the dual targeting peptide of Thr-tRNA synthetase and its interaction with Tom20 in Arabidopsis thaliana. Our findings show that the targeting peptide is mostly unstructured in buffer, with a propensity to form α-helical structure in one region, S6-F27, and a very weak β-strand propensity for Q34-Q38. The α-helical structured region has an amphiphilic character and a φχχφφ motif, both of which have previously been shown to be important for mitochondrial import. Using NMR we have mapped out two regions in the peptide that are important for Tom20 recognition: one of them, F9-V28, overlaps with the amphiphilic region, and the other comprises residues L30-Q39. Our results show that the targeting peptide may interact with Tom20 in several ways. Furthermore, our results indicate a weak, dynamic interaction. The results provide for the first time molecular details on the interaction of the Tom20 receptor with a dual targeting peptide. © 2012 The Authors Journal compilation © 2012 FEBS.

  17. Miscellanea Herpetologica Sanctithomae, with a provisional checklist of the terrestrial herpetofauna of São Tomé, Príncipe and Annobon islands.

    Science.gov (United States)

    CerÍaco, Luis M P; Marques, Mariana P; Bauer, Aaron M

    2018-02-26

    Five problematic cases regarding the presence of reptile taxa on the island of São Tomé (Gulf of Guinea) are reviewed. These cases deal with 1) the past presence of crocodilians in the island, 2) the putative type locality of Dipsas pulverulenta Fischer, 1856, 3) the dubious presence of a mamba (genus Dendroaspis) on the island, 4) an erroneous reference to the presence of Gastropyxis smaragdina, and 5) two specimens (Psammophis lineatus and Psammophis elegans) from Carl Weiss collection, currently deposited in the Zoological Museum of Hamburg and wrongly labelled as being from São Tomé island. A provisional checklist to the terrestrial herpetofauna of the three oceanic islands of the Gulf of Guinea-São Tomé, Príncipe and Annobon-is presented in order to clarify the current numbers of the endemics of each island, as well as to review and present current research.

  18. Hydrography, Polk County was flown in May 1996. Ayres Associates, Madison, digitized all hydrography features and provided this data as a two-dimensional AutoCAD drawing file. In 2006 Polk County converted the AutoCAD hydrography file into and shapefile creating the h, Published in 1996, 1:24000 (1in=2000ft) scale, Polk County Government.

    Data.gov (United States)

    NSGIC Local Govt | GIS Inventory — Hydrography dataset current as of 1996. Polk County was flown in May 1996. Ayres Associates, Madison, digitized all hydrography features and provided this data as a...

  19. Reconstituted TOM core complex and Tim9/Tim10 complex of mitochondria are sufficient for translocation of the ADP/ATP carrier across membranes.

    Science.gov (United States)

    Vasiljev, Andreja; Ahting, Uwe; Nargang, Frank E; Go, Nancy E; Habib, Shukry J; Kozany, Christian; Panneels, Valérie; Sinning, Irmgard; Prokisch, Holger; Neupert, Walter; Nussberger, Stephan; Rapaport, Doron

    2004-03-01

    Precursor proteins of the solute carrier family and of channel forming Tim components are imported into mitochondria in two main steps. First, they are translocated through the TOM complex in the outer membrane, a process assisted by the Tim9/Tim10 complex. They are passed on to the TIM22 complex, which facilitates their insertion into the inner membrane. In the present study, we have analyzed the function of the Tim9/Tim10 complex in the translocation of substrates across the outer membrane of mitochondria. The purified TOM core complex was reconstituted into lipid vesicles in which purified Tim9/Tim10 complex was entrapped. The precursor of the ADP/ATP carrier (AAC) was found to be translocated across the membrane of such lipid vesicles. Thus, these components are sufficient for translocation of AAC precursor across the outer membrane. Peptide libraries covering various substrate proteins were used to identify segments that are bound by Tim9/Tim10 complex upon translocation through the TOM complex. The patterns of binding sites on the substrate proteins suggest a mechanism by which portions of membrane-spanning segments together with flanking hydrophilic segments are recognized and bound by the Tim9/Tim10 complex as they emerge from the TOM complex into the intermembrane space.

  20. A base sócio-histórica na construção do protagonista em As Aventuras de Tom Sawyer

    Directory of Open Access Journals (Sweden)

    Ângela Tavares Nates Moreira

    2015-06-01

    Full Text Available A obra The Adventures of Tom Sawyer, escrita pelo autor norte americano Samuel Langhorne Clemens, mais conhecido pelo pseudônimo Mark Twain, é considerada, hoje, a narrativa que inaugurou a literatura infanto-juvenil, no século XIX. Essa narrativa ganha maior expressividade devido a sua escrita de caráter regionalista utilizado pelo autor. Com a publicação de As Aventuras de Tom Sawyer, Mark Twain percorre o ambiente literário, com traços marcados pelo humor, pelo Realismo e pelo Regionalismo. Este trabalho objetiva analisar os fragmentos da fala de Tom e aspectos sócio-históricos de uma época de mudanças.  A finalidade é considerar o processo de transição do protagonista, dentro do romance. Desse modo, foram selecionados alguns fragmentos que revelam pontos Realistas. Após a leitura da obra, foram verificados e extraídos fragmentos representativos do jovem protagonista, tais como crenças religiosas, compreensão de mundo e valores morais. O filtro analítico se pauta no trabalho de teóricos como Bakhtin (2010, Watt (2010 e Blair (1967, entre outros, que contribuíram com informações sobre o desenvolvimento político, cultural e religioso das famílias americanas do Centro-Oeste dos Estados Unidos do século XIX. Serão abordadas as teorias sobre o personagem, a partir das reflexões de Gancho (2006 e Candido (2007. Os vários fragmentos analisados permitiram-nos chegar à conclusão sobre o modo como a transição do jovem protagonista foi influenciada, quais as características que revelam suas preferências e opiniões, e, por acréscimo, verificar que muitas dessas respostas poderão ser constatadas em conformidade com o período da época que, “irrevogavelmente”, são considerados intrínsecos na vida de Tom Sawyer.Palavras-chave: protagonista; regionalismo; realismo; Tom Sawyer.

  1. Physico-chemical and sensory characterization of fruit jams of S. Tomé and Príncipe

    Directory of Open Access Journals (Sweden)

    Elsa Ramalhosa

    2017-05-01

    Full Text Available Introduction: São Tomé and Príncipe has a wide variety of fruit trees, being most of the fruits consumed in fresh. In certain periods of the year, fruits are available at significant amounts; however, it is not common to use the surplus of those fruits. Thus, this excess may be used in the preparation of other fruit based products (ex. jams, in order to increase product diversity and allow the annual consumption of these seasonal fruits. Objetives: Valorise fruits’ production in S. Tomé and Príncipe. Methods: Preparation of jams of banana, ambarella, guava (dark and light and papaya, with two levels of sugar, and perform their physico-chemical characterization (color, pH, moisture and acidity. Furthermore, sensory analysis was also done, through preference and acceptability tests. Results: The jams prepared had different colours, acidity values, and moisture and ash contents, demonstrating the possibility of producing different products by changing the formulation. Regarding jams preference, 60% of the consumers preferred the less sweet in the case of banana and guava (light, whereas, over 67% of the panellists preferred the sweetest ambarella jam. Concerning dark guava and papaya, the percentages were similar for both sugar contents. For all attributes analysed (appearance, colour, taste, acidity, sweetness and global evaluation, most of the panellists liked slightly all jams. Conclusion: Jams production in S. Tomé and Príncipe may be a promising activity.

  2. Mida teeb sinu organisatsioon, et olla keskkonnasõbralik? / Liis Elmi, Monika Kuzmina, Kairit Kolskar, Kristina Toms...[jt.

    Index Scriptorium Estoniae

    2008-01-01

    Küsimusele vastavad: BEST-Esonia juhatuse liige Liisi Elmi, Rahvaliidu Noored juhatuse esimees Monika Kuzmina, Noored Sotsiaaldemokraadid president Kairit Kolskar, AIESEC president Kristina Toms, Eesti Psühholoogiaüliõpilaste Ühenduse juhatuse liige Andres Vegel

  3. Türk Spor Basınında Cinsiyet Ayrımcılığı: Fotomaç ve Fanatik Gazeteleri Örneği / Gender Discrimination in Turkish Sport Press: A Case Study on Fotomaç and Fanatik Newspapers

    Directory of Open Access Journals (Sweden)

    Mehmet BÜYÜKAFŞAR

    2016-07-01

    Full Text Available Toplumsal değerler sistemi erkekliğe ayrıcalıklı bir konum sunmaktadır. Erkekler, toplumsal alanda kendilerine yüklenen ağır işler sebebiyle bu ayrıcalıklı konumu hak ettiklerini düşünürler. Ailede başlayan toplumsal cinsiyet öğrenimi, sosyal ilişkilerle devam ettirilir. Bu öğrenimi kitlelere yayan bir araç olarak medya, toplumsallaşma sürecinde önemli bir rol oynamaktadır. Toplumsal cinsiyetlerine göre kadınlığı ve erkekliği belirleyen ayrıştırma, ayrımcılık anlamı yüklenerek, sosyal kurumlar tarafından toplumun her alanında sürdürülmektedir. Ataerkil sisteme dayalı toplum yapısı, cinsiyet temelli ayrımcılığın ortaya çıkmasındaki başlıca sebeplerden birisidir. Ataerkil topluluklarda kadınlar her zaman geleneksel rolleriyle var olurlar. Çocukları büyütmek ve temizlik yapmak gibi sorumluluklar yüklenen kadının aksine erkek, gücün ve dayanıklılığın simgesi olarak görülür ve önemli işlerle görevlendirilir. Toplumun her alanında olduğu gibi kadınlar spor alanında da ikinci plana itilmektedir. Güç, rekabet, hırs ve çatışma konularıyla özdeşleştirilen spor alanı, erkekler kadar fiziksel güce sahip olmayan kadınları yok saymaktadır. Bu nedenlerden dolayı, spordaki kadın ve erkek eşitsizliği, bu çalışmanın odaklandığı temel noktadır. Spor basınının haber söylemi aracılığıyla yayılan erkek egemenliği konusu da bu çalışmanın üzerinde durduğu diğer bir önemli konudur. Bu bağlamda Türk spor basını, çalışmanın araştırma bölümü için seçilmiştir. Türk spor basının en önde gelen iki gazetesi, Fotomaç ve Fanatik gazetelerin 2013, 2014 ve 2015 yıllarındaki birer haftasına ait sayıları incelenip, cinsiyet ayrımcılığına yönelik bulgular araştırılmıştır. / The system of social values attributes masculinity an exclusive position. The man considers deserving this privileged position because of handling

  4. Orfandad, exilio y utopía en el pensamiento literario de Tomás Segovia

    Directory of Open Access Journals (Sweden)

    Juan Pascual Gay

    2013-07-01

    Full Text Available Este texto pretende una aproximación al desarrollo de ciertas ideas centrales presentes en la obra de Tomás Segovia: exilio, orfandad y utopía. En el caso del exilio se hablará del que se corresponde con una noción más bien abstracta antes que la histórica concreta; el estado de orfandad como un exilio radical conculcado por el reconocimiento, y la utopía como un lugar posible de ser vivido desde el respeto por el otro, por el mero hecho de ser hombre. This text aims to an approach to the development of certain central ideas present in the work of Tomás Segovia: exile, orphanhood, and utopia. In the case of the exile will discuss which corresponds to a rather abstract notion rather than the historic concrete; the State of orphanhood as a radical exile violated by the recognition, and utopia as a possible place of living out of respect on the other, by the mere fact of being a man.

  5. Diagnostic value of an abnormal smear in non-pregnant women. Evaluation of positive smear from the surface of the portio obtained by the cottonswab method or by the dry wooden Ayre spatula and the relevance of positive smear from the endocervix and/or from the surface of the portio

    DEFF Research Database (Denmark)

    Lundvall, L; Højgaard, L L; Højgaard, K

    1990-01-01

    During a 3-4 year period, 324 women with a positive smear were registered consecutively and prospectively and divided into two groups according to the design of the investigation. In one group the smear was taken with an Ayre spatula and in the other group with a cotton swab. The purpose of this ...

  6. Ejercicios y penitencia en la obra de Tomé de Jesus

    Directory of Open Access Journals (Sweden)

    Eduardo Javier Alonso Romo

    2009-01-01

    Full Text Available The present essay aims at approaching the classic Trabalhos de Jesus, posthumous work of the Augustinian friar of sixteenth century Tomé de Jesus, through a perspective of exercises of penance, inside the most extended field of the spiritual exercises. Questions are analysed like the methodology, the prayer practices and of spiritual discernment, the dualism between inner penitence and exterior penitences, as well as the advices to break down the temptations, and the uses for the examination of conscience and the confession. The author is placed in relation with other peninsular authors of that time specially saint Ignatius of Loyola.

  7. Semen quality and interval to sterility in tom cats treated with a 9.4 mg deslorelin implant.

    Science.gov (United States)

    Romagnoli, Stefano; Baldan, Anna; Righetti, Camilla; Milani, Chiara; Mollo, Antonio; Stelletta, Calogero

    2017-02-01

    Objectives Gonadotropin-releasing hormone (GnRH) agonists like deslorelin are being increasingly used in tom cats for their efficacy in controlling reproductive behaviour and fertility. Deslorelin implants have been widely available in Europe since 2008. Little, if anything, is known about the interval between treatment and onset of sterility, as well as semen quality, after treatment in tom cats. The purpose of this study was to investigate semen quality and interval to sterility in tom cats treated with a 9.4 mg deslorelin implant. Methods Fifteen healthy adult tom cats were treated with a 9.4 mg deslorelin implant (Suprelorin 12). For each cat, semen collection and a GnRH stimulation test (intramuscular administration of 50 μg gonadorelin [Fertagyl], followed by blood sampling 1 h later, to assay serum testosterone) were performed on the first consultation and then repeated every 15 days until complete sterility was achieved. Semen collection was performed by introducing a 14 cm, open-end feline catheter (Argyle) 9 cm into the distal urethra 10 mins after sedation by intramuscular injection of 100 μg/kg medetomidine (Domitor). Results Semen collection was not successful in all cats at each attempt. In the first month after treatment, the semen of only four cats could be evaluated, while the semen of eight cats could be evaluated during the second and third months of the study. Semen quality (ejaculate volume, progressive motility and morphological abnormalities) improved slightly during the first 19-25 days in 2/4 cats, and in 1/4 cats motility was still very high (80%) 25 days post-treatment (PT), but we have no data regarding fertility prior to treatment in this cat. The last cat never produced spermatozoa. Subsequently, semen quality gradually worsened in all cats from 30 days onwards. At 70 days PT, one cat was still potentially fertile. After 72 days all cats were sterile. Conclusions and relevance Semen quality increased slightly in treated cats during

  8. Optimisation of tomato Micro-tom regeneration and selection on glufosinate/Basta and dependency of gene silencing on transgene copy number.

    Science.gov (United States)

    Khuong, Thi Thu Huong; Crété, Patrice; Robaglia, Christophe; Caffarri, Stefano

    2013-09-01

    An efficient protocol of transformation and selection of transgenic lines of Micro-tom, a widespread model cultivar for tomato, is reported. RNA interference silencing efficiency and stability have been investigated and correlated with the number of insertions. Given its small size and ease of cultivation, the tomato (Solanum lycopersicon) cultivar Micro-tom is of widespread use as a model tomato plant. To create and screen transgenic plants, different selectable markers are commonly used. The bar marker carrying the resistance to the herbicide glufosinate/Basta, has many advantages, but it has been little utilised and with low efficiency for identification of tomato transgenic plants. Here we describe a procedure for accurate selection of transgenic Micro-tom both in vitro and in soil. Immunoblot, Southern blot and phenotypic analyses showed that 100 % of herbicide-resistant plants were transgenic. In addition, regeneration improvement has been obtained by using 2 mg/l Gibberellic acid in the shoot elongation medium; rooting optimisation on medium containing 1 mg/l IAA allowed up to 97 % of shoots developing strong and very healthy roots after only 10 days. Stable transformation frequency by infection of leaf explants with Agrobacterium reached 12 %. Shoots have been induced by combination of 1 mg/l zeatin-trans and 0.1 mg/l IAA. Somatic embryogenesis of cotyledon on medium containing 1 mg/l zeatin + 2 mg/l IAA is described in Micro-tom. The photosynthetic psbS gene has been used as reporter gene for RNA silencing studies. The efficiency of gene silencing has been found equivalent using three different target gene fragments of 519, 398 and 328 bp. Interestingly, silencing efficiency decreased from T0 to the T3 generation in plants containing multiple copies of the inserted T-DNA, while it was stable in plants containing a single insertion.

  9. Effect of object location on the density measurement and Hounsfield conversion in a NewTom 3G cone beam computed tomography unit.

    Science.gov (United States)

    Lagravère, M O; Carey, J; Ben-Zvi, M; Packota, G V; Major, P W

    2008-09-01

    The purpose of this study was to determine the effect of an object's location in a cone beam CT imaging chamber (CBCT-NewTom 3G) on its apparent density and to develop a linear conversion coefficient for Hounsfield units (HU) to material density (g cm(-3)) for the NewTom 3G Scanner. Three cylindrical models of materials with different densities were constructed and scanned at five different locations in a NewTom 3G Volume Scanner. The average HU value for each model at each location was obtained using two different types of software. Next, five cylinders of different known densities were scanned at the exact centre of a NewTom 3G Scanner. The collected data were analysed using the same two types of software to determine a standard linear relationship between density and HU for each type of software. There is no statistical significance of location of an object within the CBCT scanner on determination of its density. A linear relationship between the density of an object and the HU of a scan was rho = 0.001(HU)+1.19 with an R2 value of 0.893 (where density, rho, is measured in g cm(-3)). This equation is to be used on a range between 1.42 g cm(-3) and 0.4456 g cm(-3). A linear relationship can be used to determine the density of materials (in the density range of bone) from the HU values of a CBCT scan. This relationship is not affected by the object's location within the scanner itself.

  10. Camus' Actor as Tom Stoppard's Player; A Key to Interpreting "Rosencrantz and Guildenstern Are Dead."

    Science.gov (United States)

    Zivanovic, Judith

    An examination of Albert Camus' definition of the actor in "The Myth on Sisyphus" helps to illuminate the character and role of The Player in Tom Stoppard's play and, hence, to bring light to an understanding of the philosophy of the play itself. The actor, for Camus, reveals our mortality in the face of the absurdity of our mortality,…

  11. Statecraft and Leadership in Europe: The Case of Tomáš Garrigue Masaryk

    Directory of Open Access Journals (Sweden)

    Tomas Tatinec

    2014-09-01

    Full Text Available Born to Slovaco-German-Czech poor servants, with no burning interest in politics until adult age, who even came to be called the enemy of the nation, Tomáš Masaryk managed to introduce the first Czechoslovak state on the world map in 1918, through tireless advocacy carried out (literally all around the world during the Great War, and the subsequent guidance in the newly formed republic. He was unanimously elected President four times and served in this function for eighteen years (1918-1935. Tomáš Masaryk was not a product of circumstances, but their producer and skillful employer. He showed himself particularly adroit in overcoming the against-all-odds situations, as well as the ‘regular’ crisis ones. Initially isolated, resourceless, and repudiated by his own people, he managed to unite them and to make them join his idea and struggle for a project aiming for common good. Such a CV seems remarkably appropriate for a potential leader in Europe’s most advanced uniting project, the EU (European Union. Considering the 100th anniversary of the beginning of Masaryk’s state-building journey, as well as the current crisis debates in the EU, it seems appropriate to remind ourselves of a leader with a vision, determination, skill, and principles. The EU may need precisely those to stay united.

  12. Reuniones, dispersiones. Notas sobre ideas literarias de Tomás Segovia

    Directory of Open Access Journals (Sweden)

    Juan Pascual Gay

    2014-01-01

    Full Text Available Este artículo quiere dar cuenta de diferentes ideas expuestas por Tomás Segovia a lo largo de su oficio de escritor en ensayos, cuadernos de notas y entrevistas. Segovia no desarrolló un pensamiento unitario y sistemático, sino que, más bien, desarrolla esas ideas en diferentes contextos, textos y pretextos, pero esas ideas acaban por volver siem - pre a un ideario que otorga una cohesión insospechada en su obra. Además, muchas veces, sin decirlo, deja entrever la tradición literaria y cultural a la que se adscribe y que permea su obra entera.

  13. Estimation of surface UV levels based on Meteor-3/TOMS ozone data

    Energy Technology Data Exchange (ETDEWEB)

    Borisov, Y A [Central Aerological Observatory, Moscow (Russian Federation); Geogdzhaev, I V [Moscow Inst. of Physics and Technology, Moscow (Russian Federation); Khattatov, V U [Central Aerological Observatory, Moscow (Russian Federation)

    1996-12-31

    The major consequence of ozone layer depletion for the environment is an increase of harmful ultraviolet (UV) radiation on the Earth surface and in the upper ocean. This implies the importance of environmental UV monitoring. Since the direct global monitoring is not currently possible, indirect estimations of surface UV levels may be used based on satellite ozone data (Madronich, S. 1992). Total Ozone Mapping Spectrometer (TOMS) on board the METEOR-3 satellite provided regular set of data for such estimates. During the time of its operation (August, 1991 - December, 1994) the instrument registered several ozone hole events over Antarctica, when ozone levels dropped by as much as 60 % from their unperturbed values. Probably even more alarming ozone depletions were observed over highly populated regions of middle latitudes of northern hemisphere. Radiative transfer modeling was used to convert METEOR-3/TOMS daily ozone values into regional and global maps of biologically active UV. Calculations demonstrate the effect on surface UV levels produced by ozone hole over Antarctica and ozone depletions over the territory of Russia (March, 1994). UV contour lines deviate from the normal appearance which is determined by growing southward solar elevation. UV contour lines are almost perpendicular to the ozone ones in the ozone depletions areas. The 30 % ozone depletion, over Siberia caused more than 30 % increase in noontime erythemal UV levels, which is equivalent to 10-15 degrees southward latitude displacement. Higher UV radiation increases were found in ozone hole over South America (October 1992) equivalent to about 20 degrees southward displacement

  14. TOMATOMA Update: Phenotypic and Metabolite Information in the Micro-Tom Mutant Resource.

    Science.gov (United States)

    Shikata, Masahito; Hoshikawa, Ken; Ariizumi, Tohru; Fukuda, Naoya; Yamazaki, Yukiko; Ezura, Hiroshi

    2016-01-01

    TOMATOMA (http://tomatoma.nbrp.jp/) is a tomato mutant database providing visible phenotypic data of tomato mutant lines generated by ethylmethane sulfonate (EMS) treatment or γ-ray irradiation in the genetic background of Micro-Tom, a small and rapidly growing variety. To increase mutation efficiency further, mutagenized M3 seeds were subjected to a second round of EMS treatment; M3M1 populations were generated. These plants were self-pollinated, and 4,952 lines of M3M2 mutagenized seeds were generated. We checked for visible phenotypes in the M3M2 plants, and 618 mutant lines with 1,194 phenotypic categories were identified. In addition to the phenotypic information, we investigated Brix values and carotenoid contents in the fruits of individual mutants. Of 466 samples from 171 mutant lines, Brix values and carotenoid contents were between 3.2% and 11.6% and 6.9 and 37.3 µg g(-1) FW, respectively. This metabolite information concerning the mutant fruits would be useful in breeding programs as well as for the elucidation of metabolic regulation. Researchers are able to browse and search this phenotypic and metabolite information and order seeds of individual mutants via TOMATOMA. Our new Micro-Tom double-mutagenized populations and the metabolic information could provide a valuable genetic toolkit to accelerate tomato research and potential breeding programs. © The Author 2015. Published by Oxford University Press on behalf of Japanese Society of Plant Physiologists. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  15. Estimation of surface UV levels based on Meteor-3/TOMS ozone data

    Energy Technology Data Exchange (ETDEWEB)

    Borisov, Y.A. [Central Aerological Observatory, Moscow (Russian Federation); Geogdzhaev, I.V. [Moscow Inst. of Physics and Technology, Moscow (Russian Federation); Khattatov, V.U. [Central Aerological Observatory, Moscow (Russian Federation)

    1995-12-31

    The major consequence of ozone layer depletion for the environment is an increase of harmful ultraviolet (UV) radiation on the Earth surface and in the upper ocean. This implies the importance of environmental UV monitoring. Since the direct global monitoring is not currently possible, indirect estimations of surface UV levels may be used based on satellite ozone data (Madronich, S. 1992). Total Ozone Mapping Spectrometer (TOMS) on board the METEOR-3 satellite provided regular set of data for such estimates. During the time of its operation (August, 1991 - December, 1994) the instrument registered several ozone hole events over Antarctica, when ozone levels dropped by as much as 60 % from their unperturbed values. Probably even more alarming ozone depletions were observed over highly populated regions of middle latitudes of northern hemisphere. Radiative transfer modeling was used to convert METEOR-3/TOMS daily ozone values into regional and global maps of biologically active UV. Calculations demonstrate the effect on surface UV levels produced by ozone hole over Antarctica and ozone depletions over the territory of Russia (March, 1994). UV contour lines deviate from the normal appearance which is determined by growing southward solar elevation. UV contour lines are almost perpendicular to the ozone ones in the ozone depletions areas. The 30 % ozone depletion, over Siberia caused more than 30 % increase in noontime erythemal UV levels, which is equivalent to 10-15 degrees southward latitude displacement. Higher UV radiation increases were found in ozone hole over South America (October 1992) equivalent to about 20 degrees southward displacement

  16. TOMS/Earth Probe UV Reflectivity Daily L3 Global 1x1.25 deg Lat/Lon Grid V008

    Data.gov (United States)

    National Aeronautics and Space Administration — This data product contains TOMS/Earth Probe UV Reflectivity Daily L3 Global 1x1.25 deg Lat/Lon Grid Version 8 data in ASCII format. (The shortname for this Level-3...

  17. THIR/Nimbus-7 Level 1 Cloud Data for SBUV/TOMS V001 (THIRN7L1BCLT) at GES DISC

    Data.gov (United States)

    National Aeronautics and Space Administration — THIRN7L1BCLT is the Nimbus-7 Temperature-Humidity Infrared Radiometer (THIR) Level 1 Cloud Data for SBUV/TOMS (BCLT) product and contains total cloud amounts;...

  18. The legacy of Tom Andersen: The ethics of reflecting processes.

    Science.gov (United States)

    Gehart, Diane R

    2018-03-08

    Tom Andersen and his pioneering work with reflecting conservations has had a lasting influence on the field of family therapy and mental health more broadly. Most family therapists are familiar with his contributions related to reflecting teams; however, fewer are familiar with his conceptualization of reflecting processes, which offer practical ways to approach therapeutic conversations to address challenging problems. This article provides a brief history of Andersen's career and reviews four key elements of his approach, including: (a) his way of being in relationship, (b) appropriately unusual comments, (c) inner and outer dialogs, and (d) ethics of dialogical relating. Finally, this article introduces readers to the context of the video that will be analyzed in the articles that follow in this special section. © 2018 American Association for Marriage and Family Therapy.

  19. Wolbachia Protein TomO Targets nanos mRNA and Restores Germ Stem Cells in Drosophila Sex-lethal Mutants.

    Science.gov (United States)

    Ote, Manabu; Ueyama, Morio; Yamamoto, Daisuke

    2016-09-12

    Wolbachia, endosymbiotic bacteria prevalent in invertebrates, manipulate their hosts in a variety of ways: they induce cytoplasmic incompatibility, male lethality, male-to-female transformation, and parthenogenesis. However, little is known about the molecular basis for host manipulation by these bacteria. In Drosophila melanogaster, Wolbachia infection makes otherwise sterile Sex-lethal (Sxl) mutant females capable of producing mature eggs. Through a functional genomic screen for Wolbachia genes with growth-inhibitory effects when expressed in cultured Drosophila cells, we identified the gene WD1278 encoding a novel protein we call toxic manipulator of oogenesis (TomO), which phenocopies some of the Wolbachia effects in Sxl mutant D. melanogaster females. We demonstrate that TomO enhances the maintenance of germ stem cells (GSCs) by elevating Nanos (Nos) expression via its interaction with nos mRNA, ultimately leading to the restoration of germ cell production in Sxl mutant females that are otherwise without GSCs. Copyright © 2016 Elsevier Ltd. All rights reserved.

  20. A Comparison of Seasonal and Interannual Variability of Soil Dust Aerosols Over the Atlantic Ocean as Inferred by the Toms AI and AVHRR AOT Retrievals

    Science.gov (United States)

    Cakmur, R. V.; Miller, R. L.; Tegen, Ina; Hansen, James E. (Technical Monitor)

    2001-01-01

    The seasonal cycle and interannual variability of two estimates of soil (or 'mineral') dust aerosols are compared: Advanced Very High Resolution Radiometer (AVHRR) aerosol optical thickness (AOT) and Total Ozone Mapping Spectrometer (TOMS) aerosol index (AI), Both data sets, comprising more than a decade of global, daily images, are commonly used to evaluate aerosol transport models. The present comparison is based upon monthly averages, constructed from daily images of each data set for the period between 1984 and 1990, a period that excludes contamination from volcanic eruptions. The comparison focuses upon the Northern Hemisphere subtropical Atlantic Ocean, where soil dust aerosols make the largest contribution to the aerosol load, and are assumed to dominate the variability of each data set. While each retrieval is sensitive to a different aerosol radiative property - absorption for the TOMS AI versus reflectance for the AVHRR AOT - the seasonal cycles of dust loading implied by each retrieval are consistent, if seasonal variations in the height of the aerosol layer are taken into account when interpreting the TOMS AI. On interannual time scales, the correlation is low at most locations. It is suggested that the poor interannual correlation is at least partly a consequence of data availability. When the monthly averages are constructed using only days common to both data sets, the correlation is substantially increased: this consistency suggests that both TOMS and AVHRR accurately measure the aerosol load in any given scene. However, the two retrievals have only a few days in common per month so that these restricted monthly averages have a large uncertainty. Calculations suggest that at least 7 to 10 daily images are needed to estimate reliably the average dust load during any particular month, a threshold that is rarely satisfied by the AVHRR AOT due to the presence of clouds in the domain. By rebinning each data set onto a coarser grid, the availability of

  1. Large-scale analysis of full-length cDNAs from the tomato (Solanum lycopersicum) cultivar Micro-Tom, a reference system for the Solanaceae genomics.

    Science.gov (United States)

    Aoki, Koh; Yano, Kentaro; Suzuki, Ayako; Kawamura, Shingo; Sakurai, Nozomu; Suda, Kunihiro; Kurabayashi, Atsushi; Suzuki, Tatsuya; Tsugane, Taneaki; Watanabe, Manabu; Ooga, Kazuhide; Torii, Maiko; Narita, Takanori; Shin-I, Tadasu; Kohara, Yuji; Yamamoto, Naoki; Takahashi, Hideki; Watanabe, Yuichiro; Egusa, Mayumi; Kodama, Motoichiro; Ichinose, Yuki; Kikuchi, Mari; Fukushima, Sumire; Okabe, Akiko; Arie, Tsutomu; Sato, Yuko; Yazawa, Katsumi; Satoh, Shinobu; Omura, Toshikazu; Ezura, Hiroshi; Shibata, Daisuke

    2010-03-30

    The Solanaceae family includes several economically important vegetable crops. The tomato (Solanum lycopersicum) is regarded as a model plant of the Solanaceae family. Recently, a number of tomato resources have been developed in parallel with the ongoing tomato genome sequencing project. In particular, a miniature cultivar, Micro-Tom, is regarded as a model system in tomato genomics, and a number of genomics resources in the Micro-Tom-background, such as ESTs and mutagenized lines, have been established by an international alliance. To accelerate the progress in tomato genomics, we developed a collection of fully-sequenced 13,227 Micro-Tom full-length cDNAs. By checking redundant sequences, coding sequences, and chimeric sequences, a set of 11,502 non-redundant full-length cDNAs (nrFLcDNAs) was generated. Analysis of untranslated regions demonstrated that tomato has longer 5'- and 3'-untranslated regions than most other plants but rice. Classification of functions of proteins predicted from the coding sequences demonstrated that nrFLcDNAs covered a broad range of functions. A comparison of nrFLcDNAs with genes of sixteen plants facilitated the identification of tomato genes that are not found in other plants, most of which did not have known protein domains. Mapping of the nrFLcDNAs onto currently available tomato genome sequences facilitated prediction of exon-intron structure. Introns of tomato genes were longer than those of Arabidopsis and rice. According to a comparison of exon sequences between the nrFLcDNAs and the tomato genome sequences, the frequency of nucleotide mismatch in exons between Micro-Tom and the genome-sequencing cultivar (Heinz 1706) was estimated to be 0.061%. The collection of Micro-Tom nrFLcDNAs generated in this study will serve as a valuable genomic tool for plant biologists to bridge the gap between basic and applied studies. The nrFLcDNA sequences will help annotation of the tomato whole-genome sequence and aid in tomato functional

  2. Large-scale analysis of full-length cDNAs from the tomato (Solanum lycopersicum cultivar Micro-Tom, a reference system for the Solanaceae genomics

    Directory of Open Access Journals (Sweden)

    Kikuchi Mari

    2010-03-01

    Full Text Available Abstract Background The Solanaceae family includes several economically important vegetable crops. The tomato (Solanum lycopersicum is regarded as a model plant of the Solanaceae family. Recently, a number of tomato resources have been developed in parallel with the ongoing tomato genome sequencing project. In particular, a miniature cultivar, Micro-Tom, is regarded as a model system in tomato genomics, and a number of genomics resources in the Micro-Tom-background, such as ESTs and mutagenized lines, have been established by an international alliance. Results To accelerate the progress in tomato genomics, we developed a collection of fully-sequenced 13,227 Micro-Tom full-length cDNAs. By checking redundant sequences, coding sequences, and chimeric sequences, a set of 11,502 non-redundant full-length cDNAs (nrFLcDNAs was generated. Analysis of untranslated regions demonstrated that tomato has longer 5'- and 3'-untranslated regions than most other plants but rice. Classification of functions of proteins predicted from the coding sequences demonstrated that nrFLcDNAs covered a broad range of functions. A comparison of nrFLcDNAs with genes of sixteen plants facilitated the identification of tomato genes that are not found in other plants, most of which did not have known protein domains. Mapping of the nrFLcDNAs onto currently available tomato genome sequences facilitated prediction of exon-intron structure. Introns of tomato genes were longer than those of Arabidopsis and rice. According to a comparison of exon sequences between the nrFLcDNAs and the tomato genome sequences, the frequency of nucleotide mismatch in exons between Micro-Tom and the genome-sequencing cultivar (Heinz 1706 was estimated to be 0.061%. Conclusion The collection of Micro-Tom nrFLcDNAs generated in this study will serve as a valuable genomic tool for plant biologists to bridge the gap between basic and applied studies. The nrFLcDNA sequences will help annotation of the

  3. Renewable energies in the French DOM-TOM : a study of the costs and benefits of transitioning from fossil fuels to renewable energies in the French Départements d’Outre Mer et Territoires d’Outre Mer

    OpenAIRE

    Stanley-Smith, Adam P.

    2010-01-01

    The French Départements d’Outre Mer et Territoires d’Outre Mer (DOM-TOM) are not the most populous region of France. Nor are they the most prosperous, the most important, or even centers of industrial production. Rather, the DOM-TOM possessions have a unique value in French culture: they represent the past glory of the state and its people, and the courage that lead French explorers and settlers to roam the world. Unfortunately, the DOM-TOM represents an ever growing burden upon...

  4. Strong enhancement of Penning ionization for asymmetric atom pairs in cold Rydberg gases: the Tom and Jerry effect

    KAUST Repository

    Efimov, D K

    2016-05-18

    We consider Penning ionization of Rydberg atom pairs as an Auger-type process induced by the dipole-dipole interaction and employ semiclassical formulae for dipole transitions to calculate the autoionization width as a function of the principal quantum numbers, n d, n i, of both atoms. While for symmetric atom pairs with the well-known increase of the autoionization width with increasing n 0 is obtained, the result for asymmetric pairs is counterintuitive - for a fixed n i of the ionizing atom of the pair, the autoionization width strongly increases with decreasing n d of the de-excited atom. For H Rydberg atoms this increase reaches two orders of magnitude at the maximum of the n d dependence, and the same type of counterintuitive behavior is exhibited also by Na, Rb and Cs atoms. This is a purely quantum-mechanical effect, which points towards existence of optimal (we call them \\'Tom\\' and \\'Jerry\\' for \\'big\\' and \\'small\\') pairs of Rydberg atoms with respect to autoionization efficiency. Building on the model of population redistribution in cold Rydberg gases proposed in [1], we demonstrate that population evolution following the initial laser excitation of Rydberg atoms in state n 0 would eventually lead to the formation of such Tom-Jerry pairs with which feature autoionization widths that are enhanced by several orders of magnitude compared to that of two atoms in the initial laser-excited state n 0. We also show that in the high-density regime of cold Rydberg gas experiments the ionization rate of Tom-Jerry pairs can be substantially larger than the blackbody radiation-induced photoionization rate. © 2016 IOP Publishing Ltd.

  5. Efficient isolation of pure and functional mitochondria from mouse tissues using automated tissue disruption and enrichment with anti-TOM22 magnetic beads.

    Directory of Open Access Journals (Sweden)

    Andras Franko

    Full Text Available To better understand molecular mechanisms regulating changes in metabolism, as observed e.g. in diabetes or neuronal disorders, the function of mitochondria needs to be precisely determined. The usual isolation methods such as differential centrifugation result in isolates of highly variable quality and quantity. To fulfill the need of a reproducible isolation method from solid tissues, which is suitable to handle parallel samples simultaneously, we developed a protocol based on anti-TOM22 (translocase of outer mitochondrial membrane 22 homolog antibody-coupled magnetic beads. To measure oxygen consumption rate in isolated mitochondria from various mouse tissues, a traditional Clark electrode and the high-throughput XF Extracellular Flux Analyzer were used. Furthermore, Western blots, transmission electron microscopic and proteomic studies were performed to analyze the purity and integrity of the mitochondrial preparations. Mitochondrial fractions isolated from liver, brain and skeletal muscle by anti-TOM22 magnetic beads showed oxygen consumption capacities comparable to previously reported values and little contamination with other organelles. The purity and quality of isolated mitochondria using anti-TOM22 magnetic beads was compared to traditional differential centrifugation protocol in liver and the results indicated an obvious advantage of the magnetic beads method compared to the traditional differential centrifugation technique.

  6. Cruzando fronteras nacionales: hacia una cartografía del ensayismo de Tomás Segovia

    NARCIS (Netherlands)

    Houvenaghel, E.M.H.

    2014-01-01

    El poeta y ensayista hispanomexicano Tomás Segovia (Valencia 1927 – México 2011) vivió entre diferentes mundos: es de origen español y se exilió primero a Francia y después a a México, país en el que residió durante más de cuatro décadas, antes de regresar a Francia y España en 1985. Con el fin de

  7. TOMS/Earth Probe UV Aerosol Index Monthly L3 Global 1x1.25 deg Lat/Lon Grid V008

    Data.gov (United States)

    National Aeronautics and Space Administration — This data product contains TOMS/Earth Probe UV Aerosol Index Monthly L3 Global 1x1.25 deg Lat/Lon Grid Version 8 data in ASCII format. (The shortname for this...

  8. TOMS/Nimbus-7 UV Aerosol Index Monthly L3 Global 1x1.25 deg Lat/Lon Grid V008

    Data.gov (United States)

    National Aeronautics and Space Administration — This data product contains TOMS/Nimbus-7 UV Aerosol Index Monthly L3 Global 1x1.25 deg Lat/Lon Grid Version 8 data in ASCII format. The Total Ozone Mapping...

  9. TOMS/Earth Probe Total Column Ozone Daily L3 Global 1x1.25 deg Lat/Lon Grid V008

    Data.gov (United States)

    National Aeronautics and Space Administration — This data product contains TOMS/Earth Probe Total Column Ozone Daily L3 Global 1x1.25 deg Lat/Lon Grid Version 8 data in ASCII format. (The shortname for this...

  10. TOMS/Nimbus-7 Total Column Ozone Monthly L3 Global 1x1.25 deg Lat/Lon Grid V008

    Data.gov (United States)

    National Aeronautics and Space Administration — This data product contains TOMS/Nimbus-7 Total Column Ozone Monthly L3 Global 1x1.25 deg Lat/Lon Grid Version 8 data in ASCII format. The Total Ozone Mapping...

  11. TOMS/Nimbus-7 UV Aerosol Index Daily L3 Global 1x1.25 deg Lat/Lon Grid V008

    Data.gov (United States)

    National Aeronautics and Space Administration — This data product contains TOMS/Nimbus-7 UV Aerosol Index Daily L3 Global 1x1.25 deg Lat/Lon Grid Version 8 data in ASCII format. The Total Ozone Mapping...

  12. TOMS/Nimbus-7 Total Column Ozone Daily L3 Global 1x1.25 deg Lat/Lon Grid V008

    Data.gov (United States)

    National Aeronautics and Space Administration — This data product contains TOMS/Nimbus-7 Total Column Ozone Daily L3 Global 1x1.25 deg Lat/Lon Grid Version 8 data in ASCII format. The Total Ozone Mapping...

  13. Use of the McQuarrie equation for the computation of shear viscosity via equilibrium molecular dynamics

    International Nuclear Information System (INIS)

    Chialvo, A.A.; Debenedetti, P.G.

    1991-01-01

    To date, the calculation of shear viscosity for soft-core fluids via equilibrium molecular dynamics has been done almost exclusively using the Green-Kubo formalism. The alternative mean-squared displacement approach has not been used, except for hard-sphere fluids, in which case the expression proposed by Helfand [Phys. Rev. 119, 1 (1960)] has invariably been selected. When written in the form given by McQuarrie [Statistical Mechanics (Harper ampersand Row, New York, 1976), Chap. 21], however, the mean-squared displacement approach offers significant computational advantages over both its Green-Kubo and Helfand counterparts. In order to achieve comparable statistical significance, the number of experiments needed when using the Green-Kubo or Helfand formalisms is more than an order of magnitude higher than for the McQuarrie expression. For pairwise-additive systems with zero linear momentum, the McQuarrie method yields frame-independent shear viscosities. The hitherto unexplored McQuarrie implementation of the mean-squared displacement approach to shear-viscosity calculation thus appears superior to alternative methods currently in use

  14. La iglesia de los santos Ildefonso y Tomás de Villanueva en Roma: un monumento barroco a la pietas hispanica

    Directory of Open Access Journals (Sweden)

    González Tornel, Pablo

    2015-03-01

    Full Text Available In 1667 the construction of the Hospice of Saints Ildefonso and Tomás de Villanueva began on the Roman Via Sistina. The headquarters of the Augustinian Recollects in Rome took on a particular architectural configuration directly inspired by Francesco Borromini’s Chapel of the Three Kings and a very concrete iconography linked to the political situation during the second half of the 17th century. Thus the church was decorated to create a monument to the Immaculate Conception with images of the Loreto litany adorning its walls, reinforced by paintings of the Virgins of Copacabana and Guadalupe inside. All of this, combined with the dedication of the building to Saint Tomás de Villanueva (canonized in 1658, turns the temple into a celebration of the pietas hispanica in an area of the Holy City scene of clashes for power between France and Spain.En 1667 se pone la primera piedra del Hospicio de los santos Ildefonso y Tomás de Villanueva en la Via Sistina romana. La sede de la orden de los agustinos recoletos en Roma toma una particular configuración arquitectónica, directamente inspirada en la Capilla de los Reyes Magos de Francesco Borromini, y una muy definida iconografía vinculada con la situación política de la segunda mitad del siglo XVII. Así, la iglesia se erige en un monumento a la Inmaculada Concepción concretado en las imágenes de la letanía lauretana que ornan sus muros y reforzado por las pinturas de las vírgenes de Copacabana y Guadalupe en su interior. Todo ello, junto a la advocación a Santo Tomás de Villanueva, canonizado en 1658, convierte el templo en un alegato a la pietas hispanica en un área de la ciudad que fue escenario de los enfrentamientos entre Francia y España.

  15. A study on the growth of compound semiconductor single crystal by TOM technique

    International Nuclear Information System (INIS)

    Kim, H.C.; Kwon, S.I.; Chung, M.K.; Chang, J.S.

    1981-01-01

    This paper describes the merit of the HgI 2 single crystals obtained by solution growth, 2- and 3-region temperature growth, and temperature oscillation growth for soft γ-ray detectors which can be operated at room temperature. Special efforts are put on the design, construction, and operation of the TOM (Temperature Oscillation Method) single crystal growing furnace. Experimental results show that HgI 2 detectors fabricated by vapour phase growth method usually exhibit sufficient enough detector characteristics for soft γ-ray spectrometry. However, further investigation should be carried out to eliminate detector deterioration due to polarization effect. (author)

  16. OMI/Aura TOMS-Like Ozone and Radiative Cloud Fraction Daily L3 Global 0.25x0.25 deg V003

    Data.gov (United States)

    National Aeronautics and Space Administration — The Version-003 of Level-3 Aura/OMI daily global TOMS-Like Total Column Ozone gridded product (OMTO3e) is generated by the NASA OMI science team by picking the best...

  17. Cobalt(II Complexes with N,N,N-Scorpionates and Bidentate Ligands: Comparison of Hydrotris(3,5-dimethylpyrazol-1-ylborate Tp* vs. Phenyltris(4,4-dimethyloxazolin-2-ylborate ToM to Control the Structural Properties and Reactivities of Cobalt Centers

    Directory of Open Access Journals (Sweden)

    Toshiki Nishiura

    2018-06-01

    Full Text Available Scorpionate ligands Tp* (hydrotris(3,5-dimethylpyrazol-1-ylborate and ToM (tris(4,4-dimethyloxazolin-2-ylphenylborate complexes of cobalt(II with bidentate ligands were synthesized. Both Tp* and ToM coordinate to cobalt(II in a tridentate fashion when the bidentate ligand is the less hindered acetylacetonate. In crystal structures, the geometry of cobalt(II supported by the N3O2 donor set in the Tp* complex is a square-pyramid, whereas that in the ToM complex is close to a trigonal-bipyramid. Both Tp*- and ToM-acac complexes exhibit solvatochromic behavior, although the changing structural equilibria of these complexes in MeCN are quite different. In the bis(1-methylimidazol-2-ylmethylphenylborate (LPh complexes, Tp* retains the tridentate (к3 mode, whereas ToM functions as the bidentate (к2 ligand, giving the tetrahedral cobalt(II complex. The bowl-shaped cavity derived from the six methyl groups on ToM lead to susceptibility to the bulkiness of the opposite bidentate ligand. The entitled scorpionate compounds mediate hydrocarbon oxidation with organic peroxides. Allylic oxidation of cyclohexene occurs mainly on the reaction with tert-butyl hydroperoxide (TBHP, although the catalytic efficiency of the scorpionate ligand complexes is lower than that of Co(OAc2 and Co(acac2. On cyclohexane oxidation with meta-chloroperbenzoic acid (mCPBA, both ToM and Tp* complexes function as catalysts for hydroxylation. The higher electron-donating ToM complexes show faster initial reaction rates compared to the corresponding Tp* complexes.

  18. Language and ToM Development in Autism versus Asperger Syndrome: Contrasting Influences of Syntactic versus Lexical/Semantic Maturity

    Science.gov (United States)

    Paynter, Jessica; Peterson, Candida

    2010-01-01

    Theory of mind (ToM) development by a sample of 63 children aged 5-12 years (24 with Asperger syndrome, 19 with high-functioning autism, and 20 age-matched typical developers) was assessed with a five-task false-belief battery in relation to both lexical (vocabulary) and syntactic (grammar) language skills. Contrary to some previous research, no…

  19. From the External to the Internal: Behavior Clarifications Facilitate Theory of Mind (ToM) Development in Chinese Children

    Science.gov (United States)

    Liu, Yanchun; Wang, Yijie; Luo, Rufan; Su, Yanjie

    2016-01-01

    The present study investigated how Chinese children develop theory of mind (ToM) in a language environment with limited mental state talk that is rich in behavior discourse. In Study 1, 60 mothers shared a wordless storybook with their 3-4-year-olds. The children completed two false-belief tasks and the Peabody Picture Vocabulary Test-Revised at…

  20. Toward the problem of oil and gas bearing capacity of the East Tom-Kolyvan structural zone (Western Siberia)

    International Nuclear Information System (INIS)

    Stolbova, N F; Maerkov, P O

    2014-01-01

    The vast depression in the east Tom-Kolyvan folded zone (West Siberia) has been identified by the geophysical data. The well which uncovered 4000 m deep profile of the Jurassic and Paleozoic deposits has been drilled. The relevance of the research is the oil/gas-bearing capacity evaluation of the discovered depression in this West Siberia area

  1. Spatial Politics in Tom Stoppard’s Rosencrantz and Guildenstern Are Dead

    Directory of Open Access Journals (Sweden)

    Elham Kazemi

    2017-01-01

    Full Text Available http://dx.doi.org/10.5007/2175-8026.2017v70n1p287 This article examines the notion of spatial politics in Tom Stoppard’s Rosencrantz and Guildenstern Are Dead. The two courtiers enter the politically convulsive world of Hamlet, where no legitimate power structure takes hold of the state. Their regularized political rationality ceases to apply to the world; reality violates the empirical knowledge — emplacements, geographical and spiritual directions, and generally identity — of Rosencrantz and Guildenstern. The previously defined functions of places, or heterotopias (in Foucauldian terms, are in a state of abeyance. Therefore, they are lost in the midst of the unknown sets of spatial relations; any sorts of intentional act evade them; and they die and vanish absurdly in a placeless place.

  2. Los principios del método teológico de Santo Tomás a partir de la noción de sacra doctrina

    OpenAIRE

    Scarabino, Juan Lisandro

    2012-01-01

    Con el presente artículo queremos señalar los principios del método teológico de Santo Tomás. Dicho objetivo lo abordamos desde la noción de sacra doctrina, la cual es hoy en día es una noción olvidada y de ahí proviene la dificultad para su correcta comprensión. De ahí que se tienda a identificarla con la teología, restringiéndola fuertemente. Para Santo Tomás es una noción muy importante. Por esta razón toda la primera cuestión de la Suma Teológica gira sobre ella, pues la...

  3. HIV-1 infection, response to treatment and establishment of viral latency in a novel humanized T cell-only mouse (TOM) model.

    Science.gov (United States)

    Honeycutt, Jenna B; Wahl, Angela; Archin, Nancie; Choudhary, Shailesh; Margolis, David; Garcia, J Victor

    2013-10-24

    The major targets of HIV infection in humans are CD4⁺ T cells. CD4⁺ T cell depletion is a hallmark of AIDS. Previously, the SCID-hu thy/liv model was used to study the effect of HIV on thymopoeisis in vivo. However, these mice did not develop high levels of peripheral T cell reconstitution and required invasive surgery for infection and analysis. Here, we describe a novel variant of this model in which thy/liv implantation results in systemic reconstitution with human T cells in the absence of any other human hematopoietic lineages. NOD/SCID-hu thy/liv and NSG-hu thy/liv mice were created by implanting human fetal thymus and liver tissues under the kidney capsule of either NOD/SCID or NSG mice. In contrast to NOD/SCID-hu thy/liv mice that show little or no human cells in peripheral blood or tissues, substantial systemic human reconstitution occurs in NSG-hu thy/liv. These mice are exclusively reconstituted with human T cells (i.e. T-cell only mice or TOM). Despite substantial levels of human T cells no signs of graft-versus-host disease (GVHD) were noted in these mice over a period of 14 months. TOM are readily infected after parenteral exposure to HIV-1. HIV replication is sustained in peripheral blood at high levels and results in modest reduction of CD4⁺ T cells. HIV-1 replication in TOM responds to daily administration of combination antiretroviral therapy (ART) resulting in strong suppression of virus replication as determined by undetectable viral load in plasma. Latently HIV infected resting CD4⁺ T cells can be isolated from suppressed mice that can be induced to express HIV ex-vivo upon activation demonstrating the establishment of latency in vivo. NSG-hu thy/liv mice are systemically reconstituted with human T cells. No other human lymphoid lineages are present in these mice (i.e. monocytes/macrophages, B cells and DC are all absent). These T cell only mice do not develop GVHD, are susceptible to HIV-1 infection and can efficiently maintain virus

  4. Validation of the thermal code of RadTherm-IR, IR-Workbench, and F-TOM

    Science.gov (United States)

    Schwenger, Frédéric; Grossmann, Peter; Malaplate, Alain

    2009-05-01

    System assessment by image simulation requires synthetic scenarios that can be viewed by the device to be simulated. In addition to physical modeling of the camera, a reliable modeling of scene elements is necessary. Software products for modeling of target data in the IR should be capable of (i) predicting surface temperatures of scene elements over a long period of time and (ii) computing sensor views of the scenario. For such applications, FGAN-FOM acquired the software products RadTherm-IR (ThermoAnalytics Inc., Calumet, USA; IR-Workbench (OKTAL-SE, Toulouse, France). Inspection of the accuracy of simulation results by validation is necessary before using these products for applications. In the first step of validation, the performance of both "thermal solvers" was determined through comparison of the computed diurnal surface temperatures of a simple object with the corresponding values from measurements. CUBI is a rather simple geometric object with well known material parameters which makes it suitable for testing and validating object models in IR. It was used in this study as a test body. Comparison of calculated and measured surface temperature values will be presented, together with the results from the FGAN-FOM thermal object code F-TOM. In the second validation step, radiances of the simulated sensor views computed by RadTherm-IR and IR-Workbench will be compared with radiances retrieved from the recorded sensor images taken by the sensor that was simulated. Strengths and weaknesses of the models RadTherm-IR, IR-Workbench and F-TOM will be discussed.

  5. Fray Tomás de Torquemada, iconógrafo y promotor de las artes

    Directory of Open Access Journals (Sweden)

    Caballero Escamilla, Sonia

    2009-03-01

    Full Text Available In this study the author analyses the Inquisitor Torquemada’s role in two Dominican foundations: the monasteries of Santo Tomás in Ávila and Santa Cruz in Segovia. The historical context in which they emerged and their association with inquisitorial activities converted them into ideal supports for a message designed by this Dominican friar for the purpose of conveying the prestige of the Order and the involvement of the Monarchy in the struggle against heretics. He used the arts to convey a propagandistic message, adapting older iconographic formulas to his current needs, aimed at promoting the expulsion of the Jews.

    En este trabajo se analiza la ascendencia del inquisidor Torquemada sobre dos fundaciones, el convento de Santo Tomás de Ávila y el de Santa Cruz de Segovia. El contexto histórico en el que surgen y su vinculación con la actividad inquisitorial las convierte en soportes de un mensaje hábilmente diseñado por el fraile dominico en el que pone de manifiesto el prestigio de la Orden de Santo Domingo y la implicación de la Monarquía en la lucha antiherética. Aprovechando la eficacia propagandística del lenguaje plástico, no dudará en acudir a fórmulas iconográficas del pasado adaptándolas a su momento presente, creando el caldo de cultivo necesario para lograr su objetivo, la expulsión de los judíos.

  6. TOMS/Earth-Probe Total Ozone Aerosol Index UV-Reflectivity UV-B Erythemal Irradiance Daily L3 Global 1x1.25 deg V008

    Data.gov (United States)

    National Aeronautics and Space Administration — The Total Ozone Mapping Spectrometer (TOMS) version 8 daily global gridded data consist of total column ozone, aerosol index, Lambertian effective surface...

  7. Tomáš Garrigue Masaryk v českých diskusích o literárním realismu

    Czech Academy of Sciences Publication Activity Database

    Hrdina, Martin

    2014-01-01

    Roč. 17, č. 1 (2014), s. 183-203 ISSN 1213-2144 R&D Projects: GA ČR GPP406/12/P839 Institutional support: RVO:68378068 Keywords : Masaryk, Tomáš Garrigue * Zola, Émile * literary realism * naturalism * empirical aesthetics Subject RIV: AJ - Letters, Mass-media, Audiovision

  8. Plant nutritional status modulates glutamine synthetase levels in ripe tomatoes (Solanum lycopersicum cv. Micro-Tom).

    Science.gov (United States)

    Scarpeci, Telma E; Marro, Martin L; Bortolotti, Santiago; Boggio, Silvana B; Valle, Estela M

    2007-02-01

    Tomato (Solanum lycopersicum) fruit ripening implies that chloroplastic proteins are degraded and new proteins are synthesized. Supplementary nutrition is frequently required when tomato plants begin to fruit and continues until the end of the plant's life cycle. Ammonium assimilation is crucial in these fruit maturation and ripening processes. Glutamine synthetase (GS; EC 6.3.1.2), the main ammonium-fixing enzyme in plants, could not be detected in red fruits of several tomato varieties when growing under standard nutrition. In this paper, we analyze the influence of the nutritional status on the ammonium assimilation capacity of ripe tomato (cv. Micro-Tom) fruit. For this purpose, GS expression and protein profiles were followed in mature green and red fruits harvested from plants grown under standard or supplemented nutrition. Under standard nutrient regime (weekly supplied with 0.5 x Hoagland solution) GS activity was found in chloroplasts (GS2) of mature green fruits, but it was not detected either in the chromoplasts or in the cytosol of red fruits. When plants were shifted to a supplemented nutritional regime (daily supplied with 0.5 x Hoagland solution), GS was found in red fruits. Also, cytosolic transcripts (gs1) preferentially accumulated in red fruits under high nutrition. These results indicate that mature green Micro-Tom fruits assimilate ammonia through GS2 under standard nutrition, while ripe red fruits accumulate GS1 under high nutrition, probably in order to assimilate the extra N-compounds made available through supplemented nutrition.

  9. PREFACE: Polycrystal Modelling with Experimental Integration: A Symposium Honoring Carlos Tomé (San Diego, CA, USA, February 27-March 3 2011) Polycrystal Modelling with Experimental Integration: A Symposium Honoring Carlos Tomé (San Diego, CA, USA, February 27-March 3 2011)

    Science.gov (United States)

    Lebensohn, Ricardo A.

    2012-03-01

    This special issue contains selected contributions from invited speakers to the 'Polycrystal Modelling with Experimental Integration: A Symposium Honoring Carlos Tomé', held as part of the 2011 TMS Annual Meeting and Exhibition, that took place on February 27-March 3, 2011 in San Diego, CA, USA. This symposium honored the remarkable contributions of Dr Carlos N Tomé to the field of mechanical behavior of polycrystalline materials, on the occasion of his 60th birthday. Throughout his career, Dr Tomé has pioneered the theoretical and numerical development of models of polycrystal mechanical behavior, with emphasis on the role played by texture and microstructure on the anisotropic behavior of engineering materials. His many contributions have been critical in establishing a strong connection between models and experiments, and in bridging different scales in the pursuit of robust multiscale models with experimental integration. Among his achievements, the numerical codes that Dr Tomé and co-workers have developed are extensively used in the materials science and engineering community as predictive tools for parameter identification, interpretation of experiments, and multiscale calculations in academia, national laboratories and industry. The symposium brought together materials scientists and engineers to address current theoretical, computational and experimental issues related to microstructure-property relationships in polycrystalline materials deforming in different regimes, including the effects of single crystal anisotropy, texture and microstructure evolution. Synergetic studies, involving different crystal plasticity-based models, including multiscale implementations of the latter, and measurements of global and local textures, internal strains, dislocation structures, twinning, phase distribution, etc, were discussed in more than 90 presentations. The papers in this issue are representative of the different length-scales, materials, and experimental and

  10. TOMS/Nimbus-7 Total Ozone Aerosol Index UV-Reflectivity UV-B Erythemal Irradiances Daily L3 Global 1x1.25 deg V008

    Data.gov (United States)

    National Aeronautics and Space Administration — The Total Ozone Mapping Spectrometer (TOMS) version 8 Daily Gridded Data consist of daily, global coverage of total column ozone, aerosol index, Lambertian effective...

  11. Modeling the Effects of Connecting Side Channels to the Long Tom River, Oregon

    Science.gov (United States)

    Appleby, C.; McDowell, P. F.

    2015-12-01

    The lower Long Tom River is a heavily managed, highly modified stream in the southwestern Willamette Valley with many opportunities for habitat improvements and river restoration. In the 1940s and 1950s, the US Army Corps of Engineers dramatically altered this river system by constructing the Fern Ridge Dam and three, large drop structures, converting the River from a highly sinuous channel to a straight, channelized stream that is interrupted by these grade control structures, and removed the majority of the riparian vegetation. As a result, juvenile spring Chinook salmon are no longer found in the Watershed and the local population of coastal cutthroat trout face limited aquatic habitat. When the river was channelized, long sections of the historical channel were left abandoned on the floodplain. Reconnecting these historical channels as side channels may improve the quality and quantity of aquatic habitat and could allow fish passage around current barriers. However, such construction may also lead to undesirable threats to infrastructure and farmland. This study uses multiple HEC-RAS models to determine the impact of reconnecting two historical channels to the lower Long Tom River by quantifying the change in area of flood inundation and identifying infrastructure in jeapordy given current and post-restoration conditions for 1.5, 5, 10, and 25-year flood discharges. Bathymetric data from ADCP and RTK-GPS surveys has been combined with LiDAR-derived topographic data to create continuous elevation models. Several types of side channel connections are modeled in order to determine which type of connection will result in both the greatest quantity of accessible habitat and the fewest threats to public and private property. In the future, this study will also consider the change in the quantity of physical salmonid habitat and map the areas prone to sedimentation and erosion using CEASAR and PHABSIM tools.

  12. The TOMS V9 Algorithm for OMPS Nadir Mapper Total Ozone: An Enhanced Design That Ensures Data Continuity

    Science.gov (United States)

    Haffner, D. P.; McPeters, R. D.; Bhartia, P. K.; Labow, G. J.

    2015-12-01

    The TOMS V9 total ozone algorithm will be applied to the OMPS Nadir Mapper instrument to supersede the exisiting V8.6 data product in operational processing and re-processing for public release. Becuase the quality of the V8.6 data is already quite high, enchancements in V9 are mainly with information provided by the retrieval and simplifcations to the algorithm. The design of the V9 algorithm has been influenced by improvements both in our knowledge of atmospheric effects, such as those of clouds made possible by studies with OMI, and also limitations in the V8 algorithms applied to both OMI and OMPS. But the namesake instruments of the TOMS algorithm are substantially more limited in their spectral and noise characterisitics, and a requirement of our algorithm is to also apply the algorithm to these discrete band spectrometers which date back to 1978. To achieve continuity for all these instruments, the TOMS V9 algorithm continues to use radiances in discrete bands, but now uses Rodgers optimal estimation to retrieve a coarse profile and provide uncertainties for each retrieval. The algorithm remains capable of achieving high accuracy results with a small number of discrete wavelengths, and in extreme cases, such as unusual profile shapes and high solar zenith angles, the quality of the retrievals is improved. Despite the intended design to use limited wavlenegths, the algorithm can also utilitze additional wavelengths from hyperspectral sensors like OMPS to augment the retreival's error detection and information content; for example SO2 detection and correction of Ring effect on atmospheric radiances. We discuss these and other aspects of the V9 algorithm as it will be applied to OMPS, and will mention potential improvements which aim to take advantage of a synergy with OMPS Limb Profiler and Nadir Mapper to further improve the quality of total ozone from the OMPS instrument.

  13. Theory of Mind (ToM) in Children with Autism or Typical Development: Links between Eye-Reading and False Belief Understanding

    Science.gov (United States)

    Peterson, Candida C.; Slaughter, Virginia

    2009-01-01

    Previous research shows that high-functioning children with autism are slow to pass "litmus" false belief tests of ToM but how this may relate to other aspects of mindreading (e.g., discerning thoughts from facial expressions) is less clear, partly for methodological reasons. Thus the joint methodological and conceptual goals of this…

  14. Obraz hilsneriády ve vzájemné korespondenci Tomáše Garrigua Masaryka a Josefa Adolfa Bulovy

    Czech Academy of Sciences Publication Activity Database

    Květová, Miroslava

    2017-01-01

    Roč. 9, č. 1 (2017), s. 51-84 ISSN 1803-9448 Institutional support: RVO:67985921 Keywords : Masaryk, Tomáš Garrigue * Bulova, Josef Adolf * correspondence Subject RIV: AB - History OBOR OECD: History (history of science and technology to be 6.3, history of specific sciences to be under the respective headings)

  15. Construction and modelling of a thermoelectric oxide module (TOM) as a demonstrator - Final report

    Energy Technology Data Exchange (ETDEWEB)

    Tomes, P.; Weidenkaff, A.

    2010-08-15

    The project aims at the development of better thermoelectric materials for the direct conversion of solar heat into electricity. The maximum output power P{sub max} and the efficiency {eta} of the conversion was measured on a series of four-leg thermoelectric oxide modules (TOM). The modules were constructed by combining two p-type (La{sub 1.98}Sr{sub 0.02}CuO{sub 4}) and two n-type (CaMn{sub 0.98}Nb{sub 0.02}O{sub 3}) thermoelements connected electrically in series and thermally in parallel. The temperature gradient {Delta}T was provided by a High-Flux Solar Simulator source (HFSS) which generates a spectrum similar to solar radiation. This project was intended to be a feasibility study for the utilization of high temperature solar heat, which could not previously be demonstrated due to the low temperature stability of conventional materials. The direct conversion was proven by this study. The measurements show an almost linear temperature profile along the thermoelectric legs. However, the maximum output power resulted in 88.8 mW for a TOM with a leg length of 5 mm at {Delta}T = 622 K and has yet to be optimized by improving the converter design and the applied materials. The highest conversion efficiency {eta} was found for a heat flux of 4 to 8 W cm{sup -2}. The dependence of {eta} on the leg length was studied as well as the influence of a graphite coating on the hot Al{sub 2}O{sub 3} surface on {Delta}T, P{sub max} and {eta}. (authors)

  16. Water quality study at the Congaree Swamp National monument of Myers Creek, Reeves Creek and Toms Creek. Technical report

    International Nuclear Information System (INIS)

    Rikard, M.

    1991-11-01

    The Congaree Swamp National Monument is one of the last significant near virgin tracts of bottom land hardwood forests in the Southeast United States. The study documents a water quality monitoring program on Myers Creek, Reeves Creek and Toms Creek. Basic water quality parameters were analyzed. High levels of aluminum and iron were found, and recommendations were made for further monitoring

  17. TOMS/Earth Probe UV-B Erythemal Local Noon Irradiance Monthly L3 Global 1x1.25 deg Lat/Lon Grid V008

    Data.gov (United States)

    National Aeronautics and Space Administration — This data product contains TOMS/Earth Probe UV-B Erythemal Local Noon Irradiance Monthly L3 Global 1x1.25 deg Lat/Lon Grid Version 8 data in ASCII format. (The...

  18. Polo gastronómico Tomás Jofré

    Directory of Open Access Journals (Sweden)

    Regina G. Schlüter

    2008-01-01

    Full Text Available El turismo gastronómico está adquiriendo cada vez mayor importancia en el mundo, independientemente de si se trata de un país desarrollado o no. En Argentina este tipo de turismo cuenta con una larga tradición, en particular referida al enoturismo que se refleja en la Fiesta Nacional de la Vendimia que se lleva a cabo desde 1936 en la provincia de Mendoza. Hacia fines del siglo XX un plan nacional de turismo hace referencias explícitas a las rutas alimentarias y a partir de allí, desde el sector privado, surgen iniciativas para desarrollar destinos en función de su gastronomía. Una de estas iniciativas se relaciona con la transformación de un pequeño pueblo en un polo gastronómico de gran atracción. En este artículo se presentan los resultados de un estudio que se hizo en el mismo para determinar el perfil de los visitantes y las motivaciones que tienen las personas para desplazarse hacia Tomás Jofré los días domingos.

  19. Overseas dispersal of Hyperolius reed frogs from Central Africa to the oceanic islands of Sao Tomé and Príncipe

    Czech Academy of Sciences Publication Activity Database

    Bell, R. C.; Drewes, R. C.; Channing, A.; Gvoždík, Václav; Kielgast, J.; Lötters, S.; Stuart, B. L.; Zamudio, K. R.

    2015-01-01

    Roč. 42, č. 1 (2015), s. 65-75 ISSN 0305-0270 Institutional support: RVO:68081766 Keywords : Central Africa * Congo River * Gulf of Guinea * Hyperolius * long -distance dispersal * oceanic island * biogeography * phylogeography * Príncipe * Sao Tomé * species tree Subject RIV: EG - Zoology Impact factor: 3.997, year: 2015

  20. TOMS/Nimbus-7 UV-B Erythemal Local Noon Irradiance Daily L3 Global 1x1.25 deg Lat/Lon Grid V008

    Data.gov (United States)

    National Aeronautics and Space Administration — This data product contains TOMS/Nimbus-7 UV-B Erythemal Local Noon Irradiance Daily L3 Global 1x1.25 deg Lat/Lon Grid Version 8 data in ASCII format. The Total Ozone...

  1. Recuperación del borde costero, la transformación de una ciudad. Tomé

    Directory of Open Access Journals (Sweden)

    Marcela Moraga Mansoulet

    2007-11-01

    Desde la visión de una ciudad industrial y textil; declarada en 1958, Puerto Mayor, para el comercio e intercambio con el extranjero, a la decadencia de este mismo puerto, producto de la llegada de ferrocarriles, y el cambio paulatino de rol de la ciudad, es que actualmente Tomé se puede definir como una ciudad en proceso de transformación y transición, dejando atrás su histórico pasado, para transformarse en una ciudad enfocada principalmente al desarrollo de turismo, como objetivo principal, de acuerdo a las necesidades de los tiempos que hoy transcurren.

  2. Annotated catalogue of the flowering plants of São Tomé and Príncipe

    Directory of Open Access Journals (Sweden)

    E. Figueiredo

    2011-12-01

    Full Text Available A catalogue of the flowering plants of the islands of São Tomé and Príncipe (Gulf of Guinea is presented. Flowering plant diversity figures are updated to: 135 families (20 introduced, 624 genera (172 introduced, 1 104 species (301 introduced plus 15 additional infraspecific taxa. At present 119 taxa (107 species and 12 infraspecific taxa are known to be endemic to the two islands. The catalogue includes accepted names, synonyms used in recent literature, common names, voucher specimens and information on habit and habitat and on plant uses, particularly medicinally.

  3. Finishing broiler toms using an estradiol 17 beta implant together with a high energy-low protein final feed.

    Science.gov (United States)

    Moran, E T; Etches, R J

    1983-06-01

    Wrolstad Small White toms were implanted with 10 mg of estradiol 17 beta monopalmitate (EMP) at 8 weeks of age. Common corn-soybean meal feeds were given through to 12 weeks, then one-half the birds from control and EMP groups received either an adequate (16% protein, 3166 kcal ME/kg) or high energy-low protein (HE-LP, 12%, 3373 kcal) feed to 14 weeks. No differences in weight gain and feed conversion occurred between EMP and control treatments at 12 weeks but at 14 weeks when the HE-LP diet had been fed the implanted birds performed better than controls. The HE-LP feed led to body weights and feed efficiencies below that of toms given adequate diet. In all cases, EMP elicited male secondary sex characteristics rather than feminization. Processing losses were increased with EMP and when the HE-LP feed had been given. Both treatments also improved finish assessment and were additive to the extent that a substantial increase in grade occurred. Effects on carcass composition, yield of commercial cuts, and cooking loss were small. Implantation, reduced meat yield percentage of breast and thigh. The increase in grade advantage from combining EMP with a feed that forced fat deposition more than compensated for the adverse effects.

  4. Relaciones entre masculinidades: Controversia en La cabaña del tío Tom Relations among Masculinities: Controversy in Uncle Tom’s Cabin

    Directory of Open Access Journals (Sweden)

    Luis Fernando Gómez R.

    2007-01-01

    Full Text Available The American novel Uncle Tom’s Cabin, written by Harriet Beecher-Stowe, has caused historical debate because of its notion of masculinity between white men and African-American slaves in the antebellum period. The description of these two antagonist forces are said to be defined by the author on extreme foundations of sentimentalist and romantic racialism that seem to distort the real objective events related to slavery in America . Beecher-Stowe was condemned by both white and black races because of the denunciation she makes of slavery as a hegemonic male institution. This article examines this polemic in Uncle Tom’s cabin, based on the sociologist R.W. Connell’s theory of relations among masculinities. From this theory, the article argues that while whites’ masculinity is determined by a sense of power based on hegemony, complicity, and subordination, blacks’, represented by uncle Tom, is portrayed as adopting weak submission and resigned marginalization. As Uncle Tom’s Cabin is the inspiration of a historical reality, this article also studies the novel in relation to factual events in which the ideals of hegemonic masculinity established slavery as a powerful institution in America .La cabaña del tío Tom, escrita por Beecher-Stowe ha causado debate histórico debido a su noción de masculinidad entre el hombre blanco y el hombre africano durante el período de la esclavitud. Se dice que la autora describe estas dos fuerzas antagónicas con fundamentos extremos de sentimentalismo y romanticismo racial, que parecen distorsionar los hechos reales relacionados con la esclavitud en Estados Unidos. Ambas razas condenaron a la novelista por la denuncia que hace de la esclavitud como una institución hegemónicamente masculina. En este artículo se examina tal polémica en La cabaña del tío Tom, a la luz de la teoría que propone el sociólogo R.W. Connell sobre relaciones entre masculinidades. A partir de ésta, se argumenta el

  5. Availability of Micro-Tom mutant library combined with TILLING in molecular breeding of tomato fruit shelf-life.

    Science.gov (United States)

    Okabe, Yoshihiro; Asamizu, Erika; Ariizumi, Tohru; Shirasawa, Kenta; Tabata, Satoshi; Ezura, Hiroshi

    2012-06-01

    Novel mutant alleles of an ethylene receptor Solanum lycopersicum ETHYLENE RESPONSE1 (SlETR1) gene, Sletr1-1 and Sletr1-2, were isolated from the Micro-Tom mutant library by TILLING in our previous study. They displayed different levels of impaired fruit ripening phenotype, suggesting that these alleles could be a valuable breeding material for improving shelf life of tomato fruit. To conduct practical use of the Sletr1 alleles in tomato breeding, genetic complementation analysis by transformation of genes carrying each allele is required. In this study, we generated and characterized transgenic lines over-expressing Sletr1-1 and Sletr1-2. All transgenic lines displayed ethylene insensitive phenotype and ripening inhibition, indicating that Sletr1-1 and Sletr1-2 associate with the ethylene insensitive phenotype. The level of ethylene sensitivity in the seedling was different between Sletr1-1 and Sletr1-2 transgenic lines, whereas no apparent difference was observed in fruit ripening phenotype. These results suggested that it is difficult to fine-tune the extent of ripening by transgenic approach even if the weaker allele (Sletr1-2) was used. Our present and previous studies indicate that the Micro-Tom mutant library combined with TILLING could be an efficient tool for exploring genetic variations of important agronomic traits in tomato breeding.

  6. Availability of Micro-Tom mutant library combined with TILLING in molecular breeding of tomato fruit shelf-life

    Science.gov (United States)

    Okabe, Yoshihiro; Asamizu, Erika; Ariizumi, Tohru; Shirasawa, Kenta; Tabata, Satoshi; Ezura, Hiroshi

    2012-01-01

    Novel mutant alleles of an ethylene receptor Solanum lycopersicum ETHYLENE RESPONSE1 (SlETR1) gene, Sletr1-1 and Sletr1-2, were isolated from the Micro-Tom mutant library by TILLING in our previous study. They displayed different levels of impaired fruit ripening phenotype, suggesting that these alleles could be a valuable breeding material for improving shelf life of tomato fruit. To conduct practical use of the Sletr1 alleles in tomato breeding, genetic complementation analysis by transformation of genes carrying each allele is required. In this study, we generated and characterized transgenic lines over-expressing Sletr1-1 and Sletr1-2. All transgenic lines displayed ethylene insensitive phenotype and ripening inhibition, indicating that Sletr1-1 and Sletr1-2 associate with the ethylene insensitive phenotype. The level of ethylene sensitivity in the seedling was different between Sletr1-1 and Sletr1-2 transgenic lines, whereas no apparent difference was observed in fruit ripening phenotype. These results suggested that it is difficult to fine-tune the extent of ripening by transgenic approach even if the weaker allele (Sletr1-2) was used. Our present and previous studies indicate that the Micro-Tom mutant library combined with TILLING could be an efficient tool for exploring genetic variations of important agronomic traits in tomato breeding. PMID:23136532

  7. Ignacio Arellano, El ingenio de Lope de Vega. Escolios a las «Rimas humanas y divinas del licenciado Tomé de Burguillos»

    Directory of Open Access Journals (Sweden)

    Bienvenido Morros Mestres

    2014-01-01

    Full Text Available Review of Ignacio Arellano,El ingenio de Lope de Vega. Escolios a las «Rimas humanas y divinas del licenciado Tomé de Burguillos», IDEA/IGAS, New York, 2012, 305 pp. ISBN: 978-1-938795-84-8.

  8. Vardarbība multiplikācijas filmā „Toms Džerijs”: pirmsskolēnu vecāki par bērnu skatīšanās paradumiem un iespējamajiem efektiem

    OpenAIRE

    Timšāne, Ērika

    2007-01-01

    Bakalaura darba temats ir „Vardarbība multiplikācijas filmā „Toms Džerijs”: pirmsskolēnu vecāki par bērnu skatīšanās paradumiem un iespējamajiem efektiem.” Pētījuma problēma ir vardarbība multiplikācijas filmā „Toms un Džerijs”, pirmsskolēnu izpratne par tās saturu. Par teorētisko bāzi kalpo Alberta Banduras Sociālās iemācīšanās teorija. Tiek aplūkotas bērnu auditorijas īpatnības, intereses un efekti, ko izraisa agresija. Kontentanalīzes mērķis ir izpētīt desmit dažādu gadu „Toms un Džer...

  9. Instituciones microfinancieras y cajas de ahorro en Santo Tomás Hueyotlipan, Puebla

    Directory of Open Access Journals (Sweden)

    Kristiano Raccanello

    2014-01-01

    Full Text Available La exigua presencia de los intermediarios financieros formales en los municipios rurales mexicanos impulsa el uso de tandas y solicitud de dinero a prestamistas, familiares o amigos. Las cajas de ahorro constituyen una alternativa a estos métodos tradicionales y aprovechan el capital social comunitario. Esta investigación, fundamentado en una muestra realizada en el municipio de Santo Tomás Hueyotlipan (Puebla, México, analiza los factores que impulsan la participación en las cajas de ahorro informales y su interacción con otros intermediarios financieros informales. Los resultados del modelo probit indican que la participación responde a la posibilidad de poder ahorrar atrayendo a aquellos individuos que no utilizan tandas, prestamistas o deudas con familiares o amigos.

  10. Effective dose in two different dental CBCT Systems: NewTom VGi and Planmeca 3D Mid

    International Nuclear Information System (INIS)

    Ghaedizirgar, Mohammad; Faghihi, Reza; Paydar, Reza; Sina, Sedigheh

    2017-01-01

    Cone beam computed tomography, CBCT, is a kind of CT scanner producing conical diverging X-rays, in which a large area of a two-dimensional detector is irradiated in each rotation. Different investigations have been performed on dosimetry of dental CBCT. As there is no special protocol for dental CBCT, CT scan protocols are used for dosimetry. The purpose of this study is measurement of dose to head and neck organs in two CBCT systems, i.e. Planmeca 3D Mid (PM) and NewTom VGi (NT), using thermoluminescence dosimetry and Rando phantom. The thermoluminescent dosimetry (TLD)-100 chips were put at the position of different organs of the head and neck. Two TLD-100 chips were inserted at each position, the dose values were measured for several different field sizes, i.e. 8 x 8, 12 x 8 and 15 x 15 cm"2 for NewTom, and 10 x 10 and 20 x 17 cm"2 for Planmeca systems. According to the results, the average effective dose in PM is much more than the NT system in the same field size, because of the greater mAs values. For routine imaging protocols used for NT, the effective dose values are 70, 73 and 121 μSv for 8 x 8, 12 x 8 and 15 x 15 cm"2 field sizes, respectively. In PM, the effective dose in 10 x 10 cm"2 and 17 x 20 cm"2 is 259 and 341 μSv, respectively. (authors)

  11. Mapping of Micro-Tom BAC-End Sequences to the Reference Tomato Genome Reveals Possible Genome Rearrangements and Polymorphisms

    Science.gov (United States)

    Asamizu, Erika; Shirasawa, Kenta; Hirakawa, Hideki; Sato, Shusei; Tabata, Satoshi; Yano, Kentaro; Ariizumi, Tohru; Shibata, Daisuke; Ezura, Hiroshi

    2012-01-01

    A total of 93,682 BAC-end sequences (BESs) were generated from a dwarf model tomato, cv. Micro-Tom. After removing repetitive sequences, the BESs were similarity searched against the reference tomato genome of a standard cultivar, “Heinz 1706.” By referring to the “Heinz 1706” physical map and by eliminating redundant or nonsignificant hits, 28,804 “unique pair ends” and 8,263 “unique ends” were selected to construct hypothetical BAC contigs. The total physical length of the BAC contigs was 495, 833, 423 bp, covering 65.3% of the entire genome. The average coverage of euchromatin and heterochromatin was 58.9% and 67.3%, respectively. From this analysis, two possible genome rearrangements were identified: one in chromosome 2 (inversion) and the other in chromosome 3 (inversion and translocation). Polymorphisms (SNPs and Indels) between the two cultivars were identified from the BLAST alignments. As a result, 171,792 polymorphisms were mapped on 12 chromosomes. Among these, 30,930 polymorphisms were found in euchromatin (1 per 3,565 bp) and 140,862 were found in heterochromatin (1 per 2,737 bp). The average polymorphism density in the genome was 1 polymorphism per 2,886 bp. To facilitate the use of these data in Micro-Tom research, the BAC contig and polymorphism information are available in the TOMATOMICS database. PMID:23227037

  12. Sindérese, o intellectus principiorum da razão prática segundo Tomás de Aquino = Synderesis, the intellectus principiorum of practical reason according to Thomas Aquinas

    Directory of Open Access Journals (Sweden)

    Abertuni, Carlos Alberto

    2011-01-01

    Full Text Available Trata-se de uma investigação sobre a teoria dos primeiros princípios da razão prática na obra de Tomás de Aquino. No centro dessa teoria está o termo “sindérese”, cujo conteúdo foi elaborado nas discussões da filosofia e da teologia medievais, a partir de sua menção na Glosa de Jerônimo a Ezequiel. Tal termo designa um conceito que apresenta um caráter inovador dentro da teoria da ação moral em comparação com a ética aristotélica. Afinal, Tomás de Aquino o entende como o hábito dos primeiros princípios da moral, equivalente ao hábito dos primeiros princípios teóricos de Aristóteles. Dessa forma, o interesse é compreender como o conceito de sindérese é recebido e desenvolvido na filosofia moral de Tomás de Aquino através da análise das três questões tradicionais: de sua natureza, de sua infalibilidade e de sua extinção

  13. Tom McCarthy, Karl Marx, and the Money on the Books

    Directory of Open Access Journals (Sweden)

    Nicholas Huber

    2017-11-01

    Full Text Available By way of contrast to recent work on the problematic of representation of capital and its prioritized aesthetic mode, visuality, this article addresses the problematic of mediation in financialized capitalism through an attention to the relationship between writing and contemporary money forms. To elaborate this problematic, mediation is deployed methodologically as well: selections from two bodies of work concerned with capitalist monetary phenomena—those of Karl Marx and the novelist Tom McCarthy—are analyzed in parallel. McCarthy’s 'oeuvre' is presented as preoccupied with monetary-inscriptive techniques and pockmarked by Marxian concepts and concerns. It is argued that 'Remainder', specifically, can be read as theorizing the relationship between money and writing under early 21st-century regimes of finance capital through its elaboration of retail loyalty accounts and the multivalent concept of ‘remainder’ or ‘surplus’. The article reads this theorization against neglected sections of Marx’s second volume of 'Capital' in which money is enigmatically treated from the perspective of bookkeeping.

  14. Multi year changes of Aerosol Optical Depth in the monsoon region of the Indian Ocean since 1986 as seen in the AVHRR and TOMS data

    Directory of Open Access Journals (Sweden)

    J. P. George

    2008-02-01

    Full Text Available Aerosol Optical Depth (AOD data based on AVHRR and TOMS was analyzed to find out the changes in the Indian Ocean from 1981 to 2004. Four regions covering Indian Ocean north of 10° S were studied in detail. The results strongly suggest that the mean value of AOD in these regions decreased from 1986–1990 to 1995–1999. The Arabian Sea and Bay of Bengal show increase thereafter whereas in the equatorial part it decreased further, during 2000–2004. The drop in AOD from the first to second period is evident in AVHRR and TOMS in the case of the Arabian Sea (North West Indian Ocean. The decrease in this case is prominent in summer. These results in general agree with the recently reported global decrease in AOD, "global brightening" and also the reversal of trend in some of the anthropogenic emissions.

  15. Proyección científica de las ideas de Tomás Romay sobre la vacuna de la viruela en la inclusa madrileña

    Directory of Open Access Journals (Sweden)

    Ramírez Martín, Susana María

    2002-12-01

    Full Text Available This paper is about scientific and medical activities of Dr Tomás Romay Chacón. He was a pioneer of the fight agianst smallpox in America. We present here a breef biography of Dr. Romay and a document about vaccination against smallpox in La Habana.

    En el artículo se pone de manifiesto la trayectoria científica y médica del Dr. Tomás Romay y Chacón. Este médico habanero es un ejemplo de lucha contra las viruelas en América. Su actividad científica no se limitó a la isla de Cuba, sino que su saber llegó hasta la Inclusa Madrileña. A esta institución benéfica llegaron sus escritos en el año 1813.

  16. Up-to-date concentrations of long-lived artificial radionuclides in the Tom and Ob rivers in the area influenced by discharges from Siberian chemical combine

    International Nuclear Information System (INIS)

    Nikitin, A.I.; Kryshev, I.I.; Bashkirov, N.I.; Valetova, N.K.; Dunaev, G.E.; Kabanov, A.I.; Katrich, I.Yu; Krutovsky, A.O.; Nikitin, V.A.; Petrenko, G.I.; Polukhina, A.M.; Selivanova, G.V.; Shkuro, V.N.

    2012-01-01

    The Siberian Chemical Combine (SCC) is located in Seversk (formerly known as Tomsk-7) in the Tomsk Region of the Russian Federation. The main contribution of radionuclides in the SCC process water discharged into the Tom River was from the single-pass reactors, now removed from service (the last SCC reactor was shutdown on June 5, 2008). The data on the concentrations of 90 Sr, 137 Cs, 239,240 Pu and other artificial radionuclides in water, bottom sediments and flood-plain soils of the Tom and Ob rivers from Tomsk to the confluence of the rivers, are presented and discussed. The results of measurements carried out after shutdown of the last SCC single-pass reactor indicated no radiologically significant consequences of SCC activities for the studied water environment compartments. Contemporary activity concentrations of long-lived artificial radionuclides 3 H, 90 Sr, 137 Cs and 239,240 Pu in river water were below the intervention levels established by current regulations of the Russian Federation for these radionuclides. The results of 3 H analysis in water from the Tom and Samuska rivers demonstrated no inflow of contaminated formation water to surface water from the sites where liquid radioactive wastes of the SCC were injected below the surface. However, the density of flood-plain soil contamination by long-lived 137 Cs in the area influenced by SCC liquid discharges was higher than regional technogenic background. There were local flood-plain areas contaminated not only by 137 Cs, but also other gamma-emitters, such as 60 Co and 152 Eu.

  17. Sağlık Kurumlarında Çalışanların Kurumda Kalma ya da Ayrılma Kararlarının Belirlenmesinde Örgütsel Bağlılığın Etkisi: İzmir İlinde Bir Araştırma

    Directory of Open Access Journals (Sweden)

    Suna AKÇA

    2017-12-01

    Full Text Available Sağlık hizmetlerinde hastalara güvenli ve kaliteli sağlık hizmeti sunmak kadar sağlık hizmet sunucularının memnuniyeti ve kuruma bağlılıkları da o kadar önemlidir. Daha verimli ve performansı yüksek çalışmayı amaç edinen sağlık kurum ve kuruluşları, çalışanlarının örgütsel bağlılıklarını artırmak için çeşitli politikalar geliştirmek zorundadırlar. Bu çalışma İzmir’de bulunan bir kamu diş merkezinde sağlık çalışanlarının örgütsel bağlılıkları ve işten ayrılma eğilimleri arasındaki ilişkiyi test etmek için yapılmıştır. Araştırma konularının arasındaki ilişkiyi test etmek için Allen ve Mayer tarafından geliştirilen “Örgütsel Bağlılık Ölçeği” kullanılmıştır. Araştırma sonuçları; sağlık çalışanlarının örgütsel bağlılıklarının düzeylerinin düşük olduğuna, örgütsel bağlılık faktörleri arasında pozitif bir ilişkinin mevcut olduğuna ve işten ayrılma düzeyleri ile negatif orantı gösterdiğine işaret etmektedir. Anahtar Kelimeler: Sağlık Kurumları, Örgütsel Bağlılık, İşten Ayrılma JEL Sınıflandırma Kodları: I19, M19

  18. İş Özellikleri, İş-Yaşam Dengesi ve Meslekten Ayrılma Niyeti Arasındaki İlişkilerin Aday Öğretmen Görüşlerine Göre İncelenmesi

    OpenAIRE

    Polat, Şule; Özdemir, Murat

    2017-01-01

    Bu araştırmada aday öğretmenlerin görüşlerine bağlı olarak öğretmenlik mesleği iş özellikleri, iş yaşam dengesi ve meslekten ayrılma niyeti arasındaki ilişki incelenmiştir. Araştırmanın çalışma grubunu, 2016-2017 eğitim öğretim yılının birinci döneminde Ankara ilinin dokuz ilçesindeki (Çankaya, Mamak, Altındağ, Keçiören, Yenimahalle, Sincan, Etimesgut, Gölbaşı ve Pursaklar) resmi ortaöğretim kurumlarında görev yapan 225 aday öğretmen oluşturmaktadır. Araştırma verileri “Öğretmenlik Mesleği İş...

  19. Race Matters… Still. Rezension zu Tom Angotti und Sylvia Morse (Hg. (2016: Zoned Out! Race, Displacement, and City Planning in New York City. New York City: Terreform.

    Directory of Open Access Journals (Sweden)

    Yuca Meubrink

    2017-06-01

    Full Text Available In ihrem Sammelband Zoned Out! identifizieren Tom Angotti und Sylvia Morse zoning als eines der Planungsinstrumente, welches die historischen Muster ethnischer Diskriminierung und Segregation in New York bis heute immer wieder reproduziert hat. [...

  20. Radioecological monitoring of the Tom' river ecosystem within zone of nuclear fuel cycle plants influence

    International Nuclear Information System (INIS)

    Leonova, G.A.; Bobrov, V.A.; Malikov, Yu.I.; Mel'gunov, M.S.; Makarova, I.V.; Toropov, A.V.

    2005-01-01

    According to the results of 2000-2002 expeditions the estimation of radioactive contamination scales in water ecosystems within zone of Siberian Chemical Industrial Complex (SCC) influence was performed. The accumulation levels of short-lived artificial radionuclides in biota components of SCC technological channel (Romashka river), and spatial radionuclide distribution in biota of ecosystem of the Tom' and Ob' rivers at different distances from the local source have been determined using biochemical indication method. The most frequently occurring species of plants, filamentous green algae and fish were selected as indicator bioobjects for the monitoring. In spectrum of radioisotopes revealed in water plants, fish and water of the Romashka river there were determined twelve short-living isotopes that denoted continuing river burial. (author)

  1. Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus

    DEFF Research Database (Denmark)

    Medina-Gomez, Carolina; Kemp, John P; Dimou, Niki L

    2017-01-01

    bone mineral density loci: WNT4, GALNT3, MEPE, CPED1/WNT16, TNFSF11, RIN3, and PPP6R3/LRP5. Variants in the TOM1L2/SREBF1 locus exert opposing effects TB-LM and TBLH-BMD, and have a stronger association with the former trait. We show that SREBF1 is expressed in murine and human osteoblasts, as well...

  2. (ReConstrução Mítica de Eva Perón no Romance Santa Evita (1996 – Tomás Eloy Martínez

    Directory of Open Access Journals (Sweden)

    Josiane Valcarenghi Ribeiro Nantes

    2017-06-01

    Full Text Available Eva Perón é um nome significativo na história política da Argentina, sua influência surtiu, e continua surtindo efeito, no povo desse país até os dias atuais. “Evita” foi odiada/amada em níveis extremos, tanto que foi considerada uma santa, um mito para muitas pessoas. Tomás Eloy Martínez escreveu o romance – Santa Evita (1995 – em que narra como viveu a esposa de Juan Domingo Perón. Nesta obra encontra-se muitos elementos que dão indícios da (remitificação de Eva, por isso tenta-se aqui, explorar como se deu a (reconstrução mitológica de Eva Perón, personagem histórica no romance Santa Evita (1996 de Tomás Eloy Martínez, e ainda, expor quais foram os procedimentos adotados pelo autor que (reconstruíram esse mito. Utiliza-se, como base teórica, Linda Hutcheon (1991 e Fleck (2007 no conceito de metaficção historiográfica, Mircea Eliade (1991 e Martín Cezar Feijó (1984 no que cabe à análise do Mito. Esta breve pesquisa se dará a partir da análise bibliográfica e de forma comparativa entre a história e a escrita ficcional do romance Santa Evita (1996 de Tomás Eloy Martínez, discute-se os elementos utilizados e o caminho percorrido para a (reconstrução do mito Eva Perón na obra citada.

  3. 'A mate or a meal' – Pre-gravid behaviour of female Anopheles gambiae from the islands of São Tomé and Príncipe, West Africa

    Directory of Open Access Journals (Sweden)

    Ferreira Conceicao

    2003-05-01

    Full Text Available Abstract Background Malaria prevalence differs between the two islands that comprise the archipelago of São Tomé and Príncipe. This may be due to differences in the biology of local Anopheles gambiae, the only vector on the islands. Survival rate and feeding frequency are two factors influencing vectorial capacity. Anophelines generally feed just once per gonotrophic (oviposition cycle. Newly emerged insects, however, may feed two or more times during their first oviposition cycle thus increasing the likelihood of becoming infected. The reasons for multiple feeding are not clearly understood and it is still uncertain whether the behaviour is facultative or obligatory. We, therefore, determined survival and sporozoite rates, and examined the behaviour of An. gambiae from the two islands during their first gonotrophic cycle. Methods The wing size of 1,410, abdominal condition of 687, gonotrophic age and mated status of 7,264 female M form An. gambiae collected by light-trap, landing catch, resting outdoors or in copula, was determined from four sites in the archipelago. Sporozoite rates assessed by ELISA in 15,533 females from São Tomé and 2,111 from Príncipe were determined. Results Estimated survival rates ranged between 0.834–0.849 per day in São Tomé and 0.801–0.818 per day in Príncipe. Sporozoite rates of 0.63% in São Tomé were significantly higher than the 0.24% from Príncipe. Overall 49% of females mated on the second night after emergence before feeding, and 51% on the third night and thus fed before mating. The likelihood of mating before feeding increased with wing size. None of the 3,776 parous insects collected showed evidence of recent mating. All but two of the 198 females collected in copula had undeveloped ovaries. Mean wing sizes and the number of insects collected in a sentinel light-trap varied but the proportion of newly emerged insects in the collection did not. The estimated survival rate of the smallest

  4. Some assembly required: Contributions of Tom Stevens' lab to the V-ATPase field.

    Science.gov (United States)

    Graham, Laurie A; Finnigan, Gregory C; Kane, Patricia M

    2018-06-01

    Tom Stevens' lab has explored the subunit composition and assembly of the yeast V-ATPase for more than 30 years. Early studies helped establish yeast as the predominant model system for study of V-ATPase proton pumps and led to the discovery of protein splicing of the V-ATPase catalytic subunit. The Vma - phenotype, characteristic of loss-of-V-ATPase activity in yeast was key in determining the enzyme's subunit composition via yeast genetics. V-ATPase subunit composition proved to be highly conserved among eukaryotes. Genetic screens for new vma mutants led to identification of a set of dedicated V-ATPase assembly factors and helped unravel the complex pathways for V-ATPase assembly. In later years, exploration of the evolutionary history of several V-ATPase subunits provided new information about the enzyme's structure and function. This review highlights V-ATPase work in the Stevens' lab between 1987 and 2017. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  5. Das citações (indiretas na discursividade do voto de Carlos Ayres Britto acerca da união homoafetiva: efeitos de sentido possíveis

    Directory of Open Access Journals (Sweden)

    Lígia NEGRI

    2015-06-01

    Full Text Available Neste artigo, trazemos o acontecimento que o voto do ministro relator Carlos Ayres Britto funda pela sua enunciação, no Supremo Tribunal Federal, referente à recente (2011 questão da união homoafetiva no Brasil, tendo como corpus de análise as citações (indiretas extraídas de afirmações de personalidades célebres (Platão, Max Scheler, Descartes, Fernando Pessoa, Nietzsche, Hegel, Jung, Caetano Veloso, Rui Barbosa, Spinoza, Sartre e Chico Xavier, postas em jogo na materialidade linguística. Discutimos os efeitos de sentido possíveis delas decorrentes, mediante a perspectiva da Análise do Discurso de orientação francesa, tendo em conta os aspectos relevantes das condições de produção do discurso, sem deixarmos de aventar os efeitos de articulação entre citações e enunciados que as circunscrevem no voto, paralelismos etc. Lançaremos, ainda, breve olhar sobre o ethos do sujeito do discurso, a partir dos efeitos de sentido das citações. Dentre outras avaliações e reflexões, concluiremos que o discurso tem como argumento maior o amor, confrontando uma FD (Formação Discursiva prototípica do judiciário, inclusive nas menções a interdiscursos religiosos. Para nosso exercício analítico, contamos especialmente com Possenti (2009, 2002, Eni Orlandi (2009, 2006, Foucault (2010, 2009, Maingueneau (1997 e Pêcheux (2009, para que constituam nosso aporte teórico.

  6. Konaklama İşletmelerinde Örgütsel Öğrenme, Örgütsel Bağlılık ve İşten Ayrılma Eğilimi Arasındaki İlişki

    OpenAIRE

    AVCI, Nilgün; KÜÇÜKUSTA, Deniz

    2009-01-01

    Çalışmanın amacı, konaklama işletmelerinde örgütsel öğrenmenin, örgütsel bağlılık ve işten ayrılma eğilimi üzerindeki etkilerini analiz etmektir. Çeşme'de faaliyet gösteren 5 adet beş yıldızlı otel araştırmaya dahil edilmiştir. Alan araştırması kapsamında, literatürden elde edilen bilgiler ışığında oluşturulan yapılandırılmış anket tekniği kullanılmış, elde edilen veriler SPSS 13.0 (Statistical Program for Social Sciences) programı ile analiz edilmiştir. Çalışmada öncelikle geçerlik ve g...

  7. Constructing Unfinalizability: A Subject Positioning Analysis of a Couple's Therapy Session Hosted by Tom Andersen.

    Science.gov (United States)

    Guilfoyle, Michael

    2018-03-08

    The notion of subject positions is a useful tool in thinking through therapeutic interactions. In this article, I discuss positioning as an everyday phenomenon, and highlight the relational and social power dynamics that shape the subject positions persons may inhabit. Analysis is presented of the positional dynamics that play out in the couple's therapy session facilitated by Tom Andersen. Analysis suggests that Andersen adopts a not-knowing, uncertain, and curious position, while constructing the couple as competent, unfinalizable persons able to negotiate the choice-points that arise in front of them. However, if subject positions are grounded in social power dynamics, the session leaves a particular question unanswered: How will these emergent positions take hold outside of the consulting room? © 2018 American Association for Marriage and Family Therapy.

  8. Issuing and Responding to Unusual Questions: A Conversation Analytic Account of Tom Andersen's Therapeutic Practice.

    Science.gov (United States)

    Smoliak, Olga; Le Couteur, Amanda; Quinn-Nilas, Christopher

    2018-03-08

    Tom Andersen is considered one of the key contributors to the development of postmodern practice. Little is known, however, about the ways in which his ideas and practices are routinely carried out in situ. We used Conversation Analysis (CA) to investigate a session of couple therapy facilitated by Andersen. We show how Andersen and client participants oriented to and addressed problems of understanding that occurred between them. The source of this trouble was Andersen's use of unusual question formulations. We offer preliminary evidence that such unusual formulations served particular interactional and institutional (i.e., therapeutic) functions in their local contexts of use. We conclude by considering some implications of this analysis-and of conversation analytic inquiry more generally-for the practice of family therapy. © 2018 American Association for Marriage and Family Therapy.

  9. El Atlas Geográfico de España de Tomás López: Análisis mediante SIG de las poblaciones del «Reyno de Jaén» (1787)

    OpenAIRE

    Martínez García, Josefina; Manzano Augliario, Francisco; San Antonio Gomez, Jose Carlos de

    2012-01-01

    El catastro es el inventario de la riqueza de un país, los primeros avances en este sentido fueron identificar las poblaciones existentes y su ubicación geográfica. En este trabajo se analiza el trabajo del cartógrafo Tomás López, primero enmarcando su vida y obra, y posteriormente se analiza Atlas Geográfico de España (AGE) de Tomás López en su edición de 1804 y en concreto la hoja n.º 64 correspondiente al Reyno de Jaén y cuya elaboración data de 1787. Para ello se propone una metodología d...

  10. Fatores associados à adequação do cuidado pré-natal e à assistência ao parto em São Tomé e Príncipe, 2008-2009

    Directory of Open Access Journals (Sweden)

    Patrícia Alexandra da Graça Dantas dos Reis

    2015-09-01

    Full Text Available Neste artigo, foram identificados fatores sociodemográficos associados com o cuidado pré-natal e com a assistência ao parto em São Tomé e Príncipe. A amostra foi composta por 1.326 nascidos vivos de mulheres de 15 a 49 anos que participaram do Inquérito Demográfico e Sanitário de São Tomé e Príncipe, 2008-2009. Foram utilizados modelos de regressão logística e multinomial multiníveis. A adequação global do cuidado pré-natal foi de 26% e da assistência ao parto de 7% quando realizado por médicos e de 76% quando realizado por enfermeiras/auxiliares. Os fatores associados ao pré-natal e à assistência ao parto adequados foram: ordem de nascimento, educação materna e o índice de bem-estar econômico. O local de residência se mostrou fator importante apenas em relação à assistência ao parto. Observou-se que os efeitos aleatórios referentes às áreas onde as mulheres residem exerceram impacto importante sobre a chance de realizar pré-natal adequado e parto com profissionais capacitados. A importância dos fatores socioeconômicos aponta para a elaboração de ações que visem reduzir a desigualdade social em São Tomé e Príncipe.

  11. Effect of deslorelin on testicular function, serum dihydrotestosterone and oestradiol concentrations during and after suppression of sexual activity in tom cats.

    Science.gov (United States)

    Gültiken, Nilgün; Aslan, Selim; Ay, Serhan Serhat; Gülbahar, Mustafa Yavuz; Thuróczy, Julianna; Koldaş, Ece; Kaya, Duygu; Fındık, Murat; Schäfer-Somi, Sabine

    2017-02-01

    Objectives The aim of the study was to evaluate the efficacy of a 4.7 mg deslorelin implant in tom cats. Methods Nine mature male cats were included in the deslorelin group and five cats in the control group. Before the study started, all cats were confirmed to have distinct sexually dimorphic behaviour. Blood samples were taken on the implantation day, at day 7 and at day 15, then monthly, in order to measure serum dihydrotestosterone (DHT) and 17beta(β)-oestradiol concentrations. The deslorelin group (n = 9) was divided into two subgroups: five cats (cats 1-5) were neutered in the postimplantation period during suppression of sexually dimorphic behaviour, and four cats (cats 6-9) were neutered after re-expression of sexually dimorphic behaviour. The control group cats (n = 5) were castrated without administration of the implant. Results Sexually dimorphic behaviours ceased within a mean ± SD of 13-58 days (23.30 ± 14.17) after implantation. DHT concentration decreased within 30 days. The mean duration of suppression was 26.5 ± 7.42 months and reactivation coincided with increased DHT values reaching preimplantation concentrations within 1 month. 17β-oestradiol concentrations significantly correlated with DHT concentrations ( P tom cats without any side effects and with full reversibility; however, duration of suppression is highly individual.

  12. Intercomparison of preliminary MFR, SBUV, TOMS, and TOVS total ozone data

    International Nuclear Information System (INIS)

    Luther, F.M.

    1992-01-01

    The High Altitude Pollution Program of the Federal Aviation Administration is sponsoring a comparative study of total ozone data derived from various satellite instruments. The instruments included in the study are the Defense Meteorological Satellite Program's Multichannel Filter Radiometer (MFR), the NASA Solar Backscatter Ultraviolet Ozone Experiment (SBUV), the NASA Total Ozone Mapping Spectrometer (TOMS), and the NOAA Tiros Operational Vertical Sounder (TOVS). The two periods chosen for data intercomparison are January 1 - February 15, 1979 and June 1-30, 1979. These two data periods cover summer and winter regimes in both hemispheres. The January 1 - February 15, 1979 period includes a significant stratospheric warming event that began about January 15. Each of the satellite instruments has its own strengths and weaknesses. No instrument is universally better than or worse than any other in terms of accuracy, although they appear to have definite biases in certain geographical areas. The differences between the satellite systems is greatest at high latitudes where cloudiness and ozone variabilities are greatest. The Dobson data show a bias and differing degrees of ozone variability between nearby Dobson stations, which indicates there may be problems with using the Dobson data as a standard for comparison. The data used in this comparative study are preliminary in nature

  13. Black Humour Spaces in Cinema and Literature: Yorgos Lanthimos' The Lobster and Tom McCarthy's Satin Island

    Directory of Open Access Journals (Sweden)

    Vincenzo Maggitti

    2016-11-01

    Full Text Available Maggitti’s essay is focused on two different expressions of black humour in today’s film and literature. After commenting on a recent proposal, by the British writer Jonathan Coe, on the whereabouts of contemporary humour, the author examines a film  (The Lobster by YorgosLanthimos and a novel (Satin Island by T. McCarthy, both portraying the present world through humorous lenses, with a disrespectful attitude to an ecologically correct behaviour. In The Lobster hunting is claimed a universal role in man to animal relation whereas Tom McCarthy turns environmental disasters into acts of worthy ecologism. In his approach to humour, Maggitti draws on its anthropological turn as its most estranging function.

  14. La libertad humana como valor primordial en Tomás de Aquino

    Directory of Open Access Journals (Sweden)

    Dietrich Lorenz

    2004-01-01

    Full Text Available Me he propuesto en este artículo acercarme a la relación que existe en Tomás de Aquino entre el concepto de persona, libertad y felicidad, teniendo presente que, en este autor, aquel que es llamado a pensar su felicidad y sus deseos, no es el hombre en abstracto, como se tiende a pensar, sino este hombre (hoc aliquid de frente y en relación a la naturaleza de la cual forma parte, frente a otros hombres con quienes convive, y frente al fin último que lo ayuda a orientarseIn this article, the author attempts to disclose the relationship between the concepts of person, liberty and happiness in Thomas Aquinas thought. To do so, the author emphasizes the point that in Aquinas' work Man is not an abstraction, as it is usually thought, but a real Man who is called to think of his happiness and desires. This man (hoc aliquid is the one who faces and relates to nature, of which he is part of, the one who faces other men he lives with, and the one who faces the ultimate end, which helps him find his orientation

  15. Growth analysis partitioning of assimilate in tomato plants cv. Micro-Tom submitted to nitrogen and pyraclostrobin

    Directory of Open Access Journals (Sweden)

    Emanuela Garbin Martinazzo

    2015-10-01

    Full Text Available This work aimed at comparing the growth and partitioning of assimilate in tomato plants cv. Micro-Tom subjected to nitrogen and pyraclostrobin. This substance favors the development of chloroplasts and the synthesis of chlorophyll. Tomato plants were submitted to the treatments: T1, complete nutrient solution without pyraclostrobin, T2, complete nutrient solution + pyraclostrobin, T3, ½ strength nutrient solution without N pyraclostrobin and T4, ½ strength nutrient solution N + pyraclostrobin. Plants were collected at regular intervals of seven days after transplantation throughout the crop cycle, with dry mass and leaf area being determined. From the primary data, growth analysis was carried out to calculate total dry matter (Wt, the instantaneous rates of dry matter production (Ct, relative growth (Rw e net assimilation (Ea, leaf area (Af, production rates (Ca and relative growth of leaf area index (Ra and leaf weight (Fw specific leaf area (Sa the dry matter partitioning between organs and number (Nfr and fresh fruit weight (Wfr. Plants of T1 showed higher Wt, Ct and Wfr compared to those of other treatments. However, the T2 plants exhibited similar Nfr to T1 plants, being superior to others. Also allocated on the total dry matter and at the end of the cycle, a higher percentage of dry matter in the seafood compared to T3 and T4 plants. Also they allocated relative to the total dry matter and at the end of the cycle, a higher percentage in fruits of plants to T3 and T4. The association between nitrogen and pyraclostrobin changes the growth and assimilated partition on tomato plants cv. Micro – Tom, and those submitted to ½ dose of nitrogen have a higher total dry matter and less final percentage of total dry matter in fruits , comparatively to those submitted to the association ½ dose of nitrogen and pyraclostrobin.

  16. Apostolate of the laity: a re-discovery of holistic post-war missiology in Scotland, with reference to the ministry of Tom Allan

    OpenAIRE

    Forsyth, Alexander Craig

    2014-01-01

    This thesis offers principles for Christian mission in the present Western milieu derived from a retrieval of the missiology in post-war Scotland of Tom Allan. Allan was a minister, evangelist and theologian of particular public prominence in Scotland and beyond in the period from 1946 to 1964. His missiology focused upon the ‘apostolate of the laity’ through the ‘contextualisation’ of Christianity and Church. It was drawn from diverse, rich sources in Scottish and European theolo...

  17. Averroes y Tomás de Aquino sobre el concepto de ciencia natural

    Directory of Open Access Journals (Sweden)

    Lértora Mendoza, Celina Ana

    2007-01-01

    Full Text Available Al comienzo del libro I de la Physica, Aristóteles plantea la pregunta por la materia y el sujeto de la ciencia natural. Esta cuestión se refiere al concepto de la ciencia cuya indagación inicia. La ciencia natural (philosophia naturalis ha sido en lo sucesivo objeto de indagaciones específicas, sobre todo en función del comentario al original aristotélico. Averroes1 dedica al tema un conciso y a la vez comprehensivo Proemio. Tomás de Aquino,2 en cambio, y al contrario de otros casos, omite un proemio metodológico, si bien el tema en sí se desarrolla al hilo del comentario del texto del Libro I. El objetivo de este trabajo es analizar las aproximaciones y las diferencias entre la lección I del Comentario al Libro I del Aquinate (donde trata el método de la philosophia naturalis y la exégesis de Averroes en su Proemio y la Summa Prima, a fin de establecer las relaciones entre ambos

  18. Meer proeven nodig om effect van hogere F-scatterwaarde te achterhalen : diffuus glas komt in de fase van fine-tuning (interview met Silke Hemming en Tom Dueck)

    NARCIS (Netherlands)

    Kierkels, T.; Hemming, S.; Dueck, T.A.

    2014-01-01

    Diffuus glas is over vijftien jaar de standaard. Wie nu nieuw bouwt, heeft veel goede redenen om voor diffuus te kiezen en vrijwel geen om het te laten, zeggen Silke Hemming en Tom Dueck van Wageningen UR Glastuinbouw. De inzichten in het nut van diffuus licht én de technische ontwikkelingen

  19. Arte y revolución: Sobre los fotomontajes olvidados de Tomás Maldonado Art and revolution: on the forgotten photomontages of Tomás Maldonado

    Directory of Open Access Journals (Sweden)

    Daniela Lucena

    2012-08-01

    Full Text Available Este artículo presenta un análisis sobre los fotomontajes realizados por el artista Tomás Maldonado entre 1946 y 1947 para Orientación, el periódico oficial del Partido Comunista Argentino. Estas producciones eran desconocidas (o silenciadas por los historiadores del arte argentino hasta los inicios de la investigación que emprendí en el año 2003 y que se materializó en mi tesis doctoral (2010, e incluso hasta hace muy poco tiempo no se incluían en el repertorio de obras del artista. Desde la perspectiva aquí propuesta, en cambio,los fotomontajes de Maldonado constituyen dos intervenciones cruciales para abordar el intenso vínculo entre arte, revolución y política que atraviesa el proyecto de la vanguardia de arte concreto argentina. Por un lado, porque remiten a la militancia de varios miembros de la Asociación Arte ConcretoInvención en las filas del comunismo local. Por otro, porque son producciones en las cuales es posible observar la estrecha relación existente entre la propuesta del concretismo argentino impulsado por Maldonado y el programa puesto en marcha por las vanguardias soviéticas en los años posteriores a la revolución bolchevique

  20. Prevalência de enteroparisitos na populaçao urbana de São Tomé - RN - estudo comparativo de um decênio

    Directory of Open Access Journals (Sweden)

    Carlos Alberto Moreira Campos

    1982-12-01

    Full Text Available Objetivando a obtenção de variáveis relacionadas aos fatores sócio-econômicos e sanitários no período de dez (10 anos, os autores colheram resultados sobre a prevalência de enteroparasitas na população urbana de São Tomé, Rio Grande do Norte, cujos dados foram coletados entre 09 a 27 de julho de 1979, empregando o método da sedimentação espontânea (Hoffmann, Pons e Janer, através de exames realizados em 826 amostras de fezes, com uma positividade de565 para as diversas parasitoses intestinais e correspondendo a uma prevalência de 68,4% em função das condições ambientais que, embora melhoradas, concorrem no processo de disseminação de helmintoses e protozooses, além de outras patologias.In view of socio-economic and sanitary changes during ten (10 years, the authors gathered data on the prevaíence of enteroparasites in the urban population of São Tomé, Rio Grande do Norte. They collected from July 9 to July 27, 1979, 826 faecal samples which they examined using the spontaneous sedimentation method (Hoffmann, Pons, and Janer. 565 were positive for the various intestinal parasites, corresponding to a prevaíence of 68,4%. Although environmetal conditions have improved, they still contributed to the dissemination intestinal protozoal and helminthic infections.

  1. Dosimetry of 3 CBCT devices for oral and maxillofacial radiology: CB Mercuray, NewTom 3G and i-CAT.

    Science.gov (United States)

    Ludlow, J B; Davies-Ludlow, L E; Brooks, S L; Howerton, W B

    2006-07-01

    Cone beam computed tomography (CBCT), which provides a lower dose, lower cost alternative to conventional CT, is being used with increasing frequency in the practice of oral and maxillofacial radiology. This study provides comparative measurements of effective dose for three commercially available, large (12'') field-of-view (FOV), CBCT units: CB Mercuray, NewTom 3G and i-CAT. Thermoluminescent dosemeters (TLDs) were placed at 24 sites throughout the layers of the head and neck of a tissue-equivalent human skull RANDO phantom. Depending on availability, the 12'' FOV and smaller FOV scanning modes were used with similar phantom positioning geometry for each CBCT unit. Radiation weighted doses to individual organs were summed using 1990 (E(1990)) and proposed 2005 (E(2005 draft)) ICRP tissue weighting factors to calculate two measures of whole-body effective dose. Dose as a multiple of a representative panoramic radiography dose was also calculated. For repeated runs dosimetry was generally reproducible within 2.5%. Calculated doses in microSv [corrected] (E(1990), E(2005 draft)) were NewTom3G (45, 59), i-CAT (135, 193) and CB Mercuray (477, 558). These are 4 to 42 times greater than comparable panoramic examination doses (6.3 microSv [corrected] 13.3 mSv). Reductions in dose were seen with reduction in field size and mA and kV technique factors. CBCT dose varies substantially depending on the device, FOV and selected technique factors. Effective dose detriment is several to many times higher than conventional panoramic imaging and an order of magnitude or more less than reported doses for conventional CT.

  2. Transport coefficients for dense hard-disk systems

    NARCIS (Netherlands)

    García-Rojo, R.; Luding, S.; Brey, J.J.

    2006-01-01

    A study of the transport coefficients of a system of elastic hard disks based on the use of Helfand-Einstein expressions is reported. The self-diffusion, the viscosity, and the heat conductivity are examined with averaging techniques especially appropriate for event-driven molecular dynamics

  3. La Chartreuse de Parme,Tom Jones et Vanity Fair : la représentation autoconsciente dans trois stades de développement

    OpenAIRE

    Vågslid, Gudfrid

    2007-01-01

    En résumé INTRODUCTION Pour ce mémoire j ai choisi trois uvres réalistes, notamment The History of Tom Jones, a Foundling publié par Henry Fielding en 1749, La Chartreuse de Parme de Stendhal (1839) et Vanity Fair, a novel without a hero de William Makepeace Thackeray qui est paru en feuilleton en 1847-48. Je me concentrerai sur la Chartreuse et me servirai d exemples des deux autres uvres pour mettre en relief celle de Stendhal. Stendhal et Fielding partageaient « le m...

  4. Meer proeven nodig om effect van hogere F-scatterwaarde te achterhalen : diffuus glas komt in de fase van fine-tuning (interview met Silke Hemming en Tom Dueck)

    OpenAIRE

    Kierkels, T.; Hemming, S.; Dueck, T.A.

    2014-01-01

    Diffuus glas is over vijftien jaar de standaard. Wie nu nieuw bouwt, heeft veel goede redenen om voor diffuus te kiezen en vrijwel geen om het te laten, zeggen Silke Hemming en Tom Dueck van Wageningen UR Glastuinbouw. De inzichten in het nut van diffuus licht én de technische ontwikkelingen schrijden nog elk jaar voort. Een update.

  5. Einstein-Kubo-Helfand and McQuarrie relations for transport coefficients

    International Nuclear Information System (INIS)

    Erpenbeck, J.J.

    1995-01-01

    Monte Carlo molecular dynamics calculations of η E (C) (t;N) for an equimolar binary mixture of hard spheres (diameter ratio of 0.4 and mass ratio of 0.03) confirm these large differences at a few mean free times, but suggest a long-time plateau value having the magnitude of the Green-Kubo result, but the values at 70 mean free times do not approach η(t;N) with increasing N. Finally, we consider the one-particle, EKH-like, McQuarrie expression for shear viscosity, showing that the Chialvo-Cummings-Evans [Phys. Rev. E 47, 1702 (1993)] ''proof'' is defective. Moreover, we demonstrate through molecular dynamics calculations for the same hard-sphere mixture that the two-particle contribution to the time-dependent viscosity, which must vanish at long times for the McQuarrie formula to be valid, in fact contributes roughly 40% of the shear viscosity at a volume of (5 √2 /2)tsum a N a σ a 3 , where N a is the number of particles of species a having diameter σ a

  6. Plastic spatula with narrow long tip provides higher satisfactory smears for Pap test.

    Science.gov (United States)

    Kaur, Pervinder; Kushtagi, Pralhad

    2013-07-01

    Ayre spatula for cervical smear collection is being used despite the suggestion that different modified spatulas provide more satisfactory sampling. To see whether the cytological pickup improves with the use of long tipped spatula. Rurally based University Hospital; crossover study. Pap smear using Ayre spatula in 500 and with plastic narrow long tip (Szalay) spatula in 500 clinic attending women was taken and analyzed. Crossover smears were taken with modified spatula in 163 and using Ayre spatula in 187 women after 2 weeks of initial smears. The same pathologist made cytological reporting for all smears and was unaware of the type of spatula used. Smears from Ayre spatula had significantly higher reports of inadequate smears (94 of 500 vs. 68 of 500 for Ayre and Szalay, respectively; P = 0.032) and it remained so even after crossover (94 of 187 vs. 70 of 163 for Ayre and Szalay, respectively; P = 0.2). Cellular quality appeared better with smears taken using Szalay spatula, but the overall abnormal smear detection rate remained similar with either collection tool (χ(2) = 1.5; P = 0.2). Proportion of satisfactory smears is higher when long tip plastic spatula is used for collection of sample.

  7. Mission Assurance: An Operating Construct for the Department of Defense

    Science.gov (United States)

    2012-02-14

    Illinois Institute of Technology in 1987 with a Bachelor of Business Administration degree with a major in Marketing and a minor in Naval Science, and The...Retrieved from EBSCOhost . 7 Prizzia, R and Helfand, G (2001) Emergency preparedness and disaster management in Hawaii. Disaster Prevention and

  8. Measles outbreak in South Africa, 2003 - 2005 ORIGINAL ARTICLES

    African Journals Online (AJOL)

    nations, including South Africa, and resulted in the virtual elimination of measles in ... Department of Immunization, Vaccines, and Biologicals, World Health Organization,. Geneva, Switzerland ..... Lancet 1996; 348: 415. 18. Helfand RF, Moss WJ, Harpaz R, Scott S, Cutts F. Evaluating the impact of the HIV pandemic.

  9. Transport Coefficients for dense hard-disk systems

    NARCIS (Netherlands)

    Garcia-Rojo, R.; Luding, Stefan; Brey, J. Javier; Ooms, G.; Hoogendoorn, C.J.

    2007-01-01

    A study of the transport coefficients of a system of elastic hard disks, based on the use of Helfand-Einstein expressions is reported. The pressure, the viscosity, and the heat conductivity are examined for different density and system-size. While most transport coefficients agree with Enskog theory

  10. On the solution of an inverse problem for confining potentials in quantum mechanics

    International Nuclear Information System (INIS)

    Gostev, V.B.; Mineev, V.S.; Frenkin, A.R.

    1982-01-01

    The problem of plotting confining (unlimitedly increasing on the infinity) potentials of the central field by the given energy spectrum is discussed. The radial Schroedinger equation has pure discrete spectrum with infinite number of levels for these potentials. The problem is solved using the Helfand-Levitan equation with a certain reference potential V(r) for which spectral characteristics differ from the given ones only in the finite number of elements. The regular solutions PHIsub(l)(E, r) of the Schroedinger equation for the reference potential V(r) are supposed to be known. The initial potential and regular solutions of the Schroedinger equation are restored by the reference potential V(r) and regular PHIsub(l)(E, r) functions by means of the known formulas. It is observed from the paper data that confining potentials with any type of spectrum can be restored. Choice of the corresponding reference potential providing Fredholm nature of the Helfand-Levitan equation is the basic problem in this case

  11. Transformation of PRT6 RNAi construct into tomato (Solanum lycopersicum) cv. Micro-Tom

    Science.gov (United States)

    Suka, Intan Elya; Chew, Bee Lynn; Goh, Hoe-Han; Isa, Nurulhikma Md

    2018-04-01

    PROTEOLYSIS 6 plays major role in the N-end rule pathway as N-recognin which functions as E3 ligase enzyme. It mediates ubiquitin processes that lead to degradation of unstable substrate protein. The aim of the current study is to transform the PRT6 gene into tomato (Solanum lycopersicum) from the cultivar Micro-Tom and to investigate its function in regulating ripening in tomato fruits. The PRT6_RNAi construct was successfully transformed into Agrobacterium C58 via heat shock method and transformed into seven days old cotyledon explants. Factors affecting transformation efficiency such as co-cultivation time and type of plant growth regulator combination were evaluated. Results from this study found that pre-cultured cotyledons from seven days old seedlings incubated for 2 days in co-cultivation medium increased shoot regeneration. Plant growth hormones zeatin combine with auxin produced a higher number of callus formation but lower shoot proliferation and transformation frequency compared to treatments of single plant hormone in the selection medium. Polymerase chain reaction (PCR) was performed on the regenerated shoots to confirm the integration of PRT6 fragment into the genome of transgenic plants. Based on PCR analysis, all putative shoots were positive transformants.

  12. Os sentidos de theologia physica para os antiqui: Tomás de Aquino leitor de Agostinho [The senses of theologia physica for the antiqui: Thomas Aquinas reads Augustine

    Directory of Open Access Journals (Sweden)

    Evaniel Brás dos Santos

    2017-05-01

    Full Text Available Explicito neste artigo que a expressão “theologia physica” atribuída aos antigos (antiqui possui dois sentidos na ST, IIa-IIae, q. 94, a. 1, resp., de Tomás de Aquino. O primeiro, atribuído a Varrão, denota um estudo restrito, uma physiologia ou mecânica na qual deus é entendido como a força imanente no mundo, locomovendo-o. O segundo, por sua vez, pertence aos platônicos (platonici e denota um estudo geral, pois aborda, além de entidades imateriais, um criador. Ambas as teologias físicas, conforme Tomás, institui filosoficamente a idolatria ao entenderem que a divindade é causa de locomoção. Embora se valha de Agostinho em sua leitura da expressão “theologia physica”, Tomás introduz discussões que estão além do texto agostiniano.  [In the article I clarify that the expression “theologia physica” attributed to the Ancients (antiqui has two senses in the ST, IIa-IIae, q. 94, a.1, resp., of Thomas Aquinas. The first, attributed to Varro, denotes a restrict study, a physiologia or mechanics in which god is understood as the immanent force in the world, moving it. The second, in turn, belongs to the Platonics (platonici and denotes a general study, for it approaches, besides immaterial entities, a creator. Both physical theologies, according to Aquinas, set up philosophically the idolatry since they understand that the divinity is cause for locomotion. Although Aquinas makes use of Augustine in his reading of the expression “theologia physica”, he introduces discussions that go beyond the Augustinian text.

  13. Dementia and well-being: A conceptual framework based on Tom Kitwood's model of needs.

    Science.gov (United States)

    Kaufmann, Elke G; Engel, Sabine A

    2016-07-01

    The topic of well-being is becoming increasingly significant as a key outcome measure in dementia care. Previous work on personhood of individuals with dementia suggests that their subjective well-being can be described in terms of comfort, inclusion, identity, occupation and attachment The study aimed to examine Tom Kitwood's model of psychological needs and well-being in dementia based on the self-report of individuals with moderate or severe dementia and to differentiate and elaborate this model in the light of the empirical qualitative data. Nineteen inhabitants of a special long-term care unit were interviewed using a semi-structured interview. Data were analysed using content analysis. Thirty components within Kitwood's model have been identified. A conceptual framework of subjective well-being in dementia was developed based on a theoretical background. The study was able to find indications that Kitwood's model has empirical relevance. Nevertheless, it requires to be extended by the domain agency. Furthermore, the study suggests that individuals with dementia are important informants of their subjective well-being. © The Author(s) 2014.

  14. SÈNECA, L. A.: Tragèdies, edició crítica de Tomàs Martínez Romero, 2 volums, Barcelona, Barcino, 1995 («Els Nostres Clàssics», Col.lecció B, núm. 14-15)

    OpenAIRE

    Pujol i Gómez, Josep

    1998-01-01

    Obra ressenyada: L. A. SÈNECA; edició crítica de Tomàs MARTÍNEZ ROMERO, Tragèdies. Barcelona: Barcino, 1995. Tomàs Martínez fa una edició crítica de les traduccions catalanes medievals de les següents tragèdies de Sèneca: 'Hercules furens', 'Thyestes', 'Thebais (Phoenissiae)', 'Hippolytus (Phaedra)' 'Oedipus', 'Troades', 'Medea' i 'Agamemnon'. A banda de l'edició, tracta qüestions com la difusió tardomedieval de Sèneca a la corona d'Aragó, la bibliografia sobre la diversitat dels mètodes d...

  15. Tomás Romay Chacón y Carlos J. Finlay Barres hitos de pensamiento cubano en salud

    Directory of Open Access Journals (Sweden)

    María Elena Macías Llanes

    Full Text Available El objetivo del texto radica en resaltar algunos elementos de pensamiento en salud de los notables médicos cubanos Tomás Romay y Carlos J. Finlay. Se analizan sus posturas y connotación acerca del nexo entre la ciencia y la sociedad. El método investigativo utilizado ha sido la revisión documental en publicaciones periódicas, libros y repositorio de tesis. Destaca en este acercamiento la conmemoración en agosto del centenario de la muerte de Finlay (La Habana, 20 de agosto de 1915. Por lo cual este sucinto trabajo constituye un homenaje a su obra y, a su vez, al ideario de vanguardia manifiesto en la labor médica de ambos hombres de ciencia.

  16. Análise florística e estrutural de sistemas silviagrícolas em Tomé-Açu, Pará

    Directory of Open Access Journals (Sweden)

    Édson Luis Bolfe

    2011-10-01

    Full Text Available O objetivo deste trabalho foi analisar a composição florística e estrutural de sistemas silviagrícolas em Tomé-Açu, Pará. Os dados dendrométricos foram obtidos por inventário em 40 parcelas amostrais, com três unidades cada uma, no total de 120 unidades de 10x10 m. Foi inventariada a média de 1.424,3 indivíduos por hectare, pertencentes a 27 famílias e a 54 espécies. Tendo-se considerado a variabilidade dos estágios vegetativos, os diferentes sistemas silviagrícolas (SAF foram divididos em quatro classes hierárquicas: SAF 1, SAF 2, SAF 3, e SAF 4, para estabelecer um sistema de classificação passível de ser utilizado em outras avaliações de campo e em classificações digitais por meio do sensoriamento remoto. Espécies observadas em outros sistemas da região amazônica também foram relevantes para este estudo, especialmente Theobroma cacao, T. grandiflorum e Euterpe oleracea que, juntas, apresentaram médias de frequência relativa de 51%, densidade relativa de 69,2%, dominância relativa de 50,1% e índice de valor de importância de 56,8%. Os dados médios de diversidade florística, abundância, área basal e valor de importância indicam os sistemas silviagrícolas da região de Tomé-Açu como sistemas de produção com potencial econômico e ambiental, se adotado manejo adequado e racional.

  17. El modelo universitario europeo en Asia: la universidad de Santo Tomás de Manila (1611) y la civilización filipina

    OpenAIRE

    Donoso Jiménez, Isaac

    2008-01-01

    La introducción del modelo universitario europeo en Asia se produjo a finales del siglo XVI por medio de la doctrina dominica en el Archipiélago Filipino, teniendo como pilar fundamental el desarrollo de la imprenta tipográfica. En 1611 se dará carta de naturaleza a la Universidad de Santo Tomás, considerada como la primera universidad de Asia, que desarrollará una labor determinante en la definición moderna del concepto de Civilización Filipina. The introduction of the European university...

  18. Medical Surveillance Monthly Report (MSMR). Volume 22, Number 12, December 2015

    Science.gov (United States)

    2015-12-01

    injury. In fact, PTSD, chronic pain, and persis- tent post-concussive symptoms have been termed the “ polytrauma clinical triad.”7–10 However, whether...SK, Clark ME, Morasco BJ, Freeman M, Campbell R, Helfand M. Systematic review of the literature on pain in patients with polytrauma including

  19. Análise florística e estrutural de sistemas silviagrícolas em Tomé-Açu, Pará.

    OpenAIRE

    BOLFE, E. L.; BATISTELLA, M.

    2012-01-01

    O objetivo deste trabalho foi analisar a composição florística e estrutural de sistemas silviagrícolas em Tomé-Açu, Pará. Os dados dendrométricos foram obtidos por inventário em 40 parcelas amostrais, com três unidades cada uma, no total de 120 unidades de 10x10 m. Foi inventariada a média de 1.424,3 indivíduos por hectare, pertencentes a 27 famílias e a 54 espécies. Tendo-se considerado a variabilidade dos estágios vegetativos, os diferentes sistemas silviagrícolas (SAF) foram divididos em q...

  20. Plastic spatula with narrow long tip provides higher satisfactory smears for Pap test

    Directory of Open Access Journals (Sweden)

    Pervinder Kaur

    2013-01-01

    Full Text Available Background: Ayre spatula for cervical smear collection is being used despite the suggestion that different modified spatulas provide more satisfactory sampling. Aims: To see whether the cytological pickup improves with the use of long tipped spatula. Setting and Design: Rurally based University Hospital; crossover study. Materials and Methods: Pap smear using Ayre spatula in 500 and with plastic narrow long tip (Szalay spatula in 500 clinic attending women was taken and analyzed. Crossover smears were taken with modified spatula in 163 and using Ayre spatula in 187 women after 2 weeks of initial smears. The same pathologist made cytological reporting for all smears and was unaware of the type of spatula used. Results: Smears from Ayre spatula had significantly higher reports of inadequate smears (94 of 500 vs. 68 of 500 for Ayre and Szalay, respectively; P = 0.032 and it remained so even after crossover (94 of 187 vs. 70 of 163 for Ayre and Szalay, respectively; P = 0.2. Cellular quality appeared better with smears taken using Szalay spatula, but the overall abnormal smear detection rate remained similar with either collection tool (χ2 = 1.5; P = 0.2. Conclusions: Proportion of satisfactory smears is higher when long tip plastic spatula is used for collection of sample.

  1. Test-retest reliability and validity of the Sniffin' TOM odor memory test.

    Science.gov (United States)

    Croy, Ilona; Zehner, Cora; Larsson, Maria; Zucco, Gesualdo M; Hummel, Thomas

    2015-03-01

    Few attempts have been made to develop an olfactory test that captures episodic retention of olfactory information. Assessment of episodic odor memory is of particular interest in aging and in the cognitively impaired as both episodic memory deficits and olfactory loss have been targeted as reliable hallmarks of cognitive decline and impending dementia. Here, 96 healthy participants (18-92 years) and an additional 19 older people with mild cognitive impairment were tested (73-82 years). Participants were presented with 8 common odors with intentional encoding instructions that were followed by a yes-no recognition test. After recognition completion, participants were asked to identify all odors by means of free or cued identification. A retest of the odor memory test (Sniffin' TOM = test of odor memory) took place 17 days later. The results revealed satisfactory test-retest reliability (0.70) of odor recognition memory. Both recognition and identification performance were negatively affected by age and more pronounced among the cognitively impaired. In conclusion, the present work presents a reliable, valid, and simple test of episodic odor recognition memory that may be used in clinical groups where both episodic memory deficits and olfactory loss are prevalent preclinically such as Alzheimer's disease. © The Author 2014. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  2. Tom Tabor, the owner of Tabor Communications, presents Wolfgang von Rüden with the Editors Choice Award of HPCwire, which was awarded to CERN for its commitment to educating the public about high-performance computing.

    CERN Multimedia

    Maximilien Brice

    2006-01-01

    Tom Tabor, the owner of Tabor Communications, presents Wolfgang von Rüden with the Editors Choice Award of HPCwire, which was awarded to CERN for its commitment to educating the public about high-performance computing.

  3. The Role of Physical Context, Verbal Skills, Non-Parental Care, Social Support, and Type of Parental Discipline in the Development of ToM Capacity in Five-Year-Old Children

    Science.gov (United States)

    Galende, Nuria; de Miguel, Manuel Sanchez; Arranz, Enrique

    2011-01-01

    The aim of this study was to analyze the influence of family context on the performance of 5-year-old children (N = 70) in theory of mind (ToM) tasks. The children's performances were assessed during individual sessions held at school. Children's verbal skills were assessed using the Peabody picture vocabulary test (PPVT). Interviews were also…

  4. India and England in the Mirror. A Post-imperial Portrait of Tom Stoppard

    Directory of Open Access Journals (Sweden)

    Lucia Esposito

    2011-11-01

    Full Text Available The paper is focused on a sophisticated radio play by Tom Stoppard, In the Native State (1991, in which the dramatist approaches the problems linked to the ethics of the British Empire in dealing with Indian culture in both the colonial and post-colonial periods. To do this, the play confronts and complexly interlaces two different sets, India in the Thirties and London in 1990, as if they were two worlds reflecting themselves in a time mirror. The issues dealt with, such as the centuries-old westernization of the Indian minds and culture on one side, and the Indianization of British language and customs on the other, are subtlety treated in art terms, as the reciprocal relationship between the two worlds conflates in the hybrid style of the portraits executed by the hand of an Indian painter who, notwithstanding, or thanks to, his mimic identity (in Homi Bhabha’s terms, becomes the mouthpiece of a fundamental ‘change of perspective’, from the Eurocentric representation of the Orient (in Edward Said’s terms to the re-appropriation of a different point of view translating the achievement of the Nationalist movement that led India to independence in the Forties.

  5. Basal testosterone concentrations after the application of a slow-release GnRH agonist implant are associated with a loss of response to buserelin, a short-term GnRH agonist, in the tom cat.

    Science.gov (United States)

    Goericke-Pesch, Sandra; Georgiev, Plamen; Fasulkov, Ivan; Vodenicharov, Angel; Wehrend, Axel

    2013-07-01

    Slow-release GnRH agonist implants are considered an effective, reversible alternative to surgical castration in male tom cats. Individual differences exist regarding the onset of efficacy and might be delayed in some animals. Single measurements of testosterone (T) might result in basal concentrations also in intact male cats. Consequently, GnRH stimulation tests are performed to measure T increase in intact animals and to differentiate castrated from intact male cats. In this study, five tom cats were treated with a 4.7-mg deslorelin implant and GnRH stimulation tests using buserelin were performed before treatment and at 4-week intervals afterward until Week 20. After the last test in Week 20 all animals were castrated. Four of five animals had basal T after 4 weeks and-in contrast to pretreatment-application of buserelin did not result in any further T increase. In one animal, T was low after implant insertion, but not basal; however, a GnRH stimulation test induced a slight increase of T in Week 8 and 16 only and no response in Weeks 4, 12, and 20. Testicular volume was significantly decreased and penile spines disappeared in all cats. Testicular histology showed mixed atrophy, but also fully elongated spermatids in three of five male cats making infertility questionable. Because of the loss of the stimulatory effect of short-term GnRH application (buserelin), it can be assumed that long-term GnRH agonists also act by some mechanisms of downregulation of pituitary GnRH receptors in the tom cat. Copyright © 2013 Elsevier Inc. All rights reserved.

  6. Azo dye removal in a membrane-free up-flow biocatalyzed electrolysis reactor coupled with an aerobic bio-contact oxidation reactor.

    Science.gov (United States)

    Cui, Dan; Guo, Yu-Qi; Cheng, Hao-Yi; Liang, Bin; Kong, Fan-Ying; Lee, Hyung-Sool; Wang, Ai-Jie

    2012-11-15

    Azo dyes that consist of a large quantity of dye wastewater are toxic and persistent to biodegradation, while they should be removed before being discharged to water body. In this study, Alizarin Yellow R (AYR) as a model azo dye was decolorized in a combined bio-system of membrane-free, continuous up-flow bio-catalyzed electrolysis reactor (UBER) and subsequent aerobic bio-contact oxidation reactor (ABOR). With the supply of external power source 0.5 V in the UBER, AYR decolorization efficiency increased up to 94.8±1.5%. Products formation efficiencies of p-phenylenediamine (PPD) and 5-aminosalicylic acid (5-ASA) were above 90% and 60%, respectively. Electron recovery efficiency based on AYR removal in cathode zone was nearly 100% at HRTs longer than 6 h. Relatively high concentration of AYR accumulated at higher AYR loading rates (>780 gm(-3) d(-1)) likely inhibited acetate oxidation of anode-respiring bacteria on the anode, which decreased current density in the UBER; optimal AYR loading rate for the UBER was 680 gm(-3) d(-1) (HRT 2.5 h). The subsequent ABOR further improved effluent quality. Overall the Chroma decreased from 320 times to 80 times in the combined bio-system to meet the textile wastewater discharge standard II in China. Copyright © 2012 Elsevier B.V. All rights reserved.

  7. 6 June 2008 - Chancellor F. Tomàs Vert, University of Valencia, visiting ATLAS control room and experimental area with Collaboration Spokesperson P. Jenni.

    CERN Multimedia

    Mona Schweizer

    2008-01-01

    6 June 2008 - Chancellor F. Tomàs Vert, University of Valencia, visiting ATLAS control room and experimental area with Collaboration Spokesperson P. Jenni. Other participants: Prof. Francisco José Botella, Director, Instituto de Fisica Corpuscular, University of València and CSIC Prof. José Peñarrocha, Dean, Faculty of Physics Prof. Antonio Ferrer, Instituto de Fisica Corpuscular, University of València and CSIC Prof. Antonio Pich, University of València, Member of IFIC (CSIC - Univ. València), Coordinator of CPAN, Spanish National Centre for Particle, Astroparticle and Nuclear Physics.

  8. FORMAS DE TRATAMENTO EM TRADUÇÕES DE “THE ADVENTURES OF TOM SAWYER”: RELAÇÕES SOCIAIS E AFETIVAS

    Directory of Open Access Journals (Sweden)

    Giselle Olivia Mantovani Dal Corno

    2015-02-01

    Full Text Available Mark Twain is a renowned realist author, known by his colloquial style and local colorism. In the novel “The adventures of Tom Sawyer”, he manages to depict oral regional language in the lines of his characters. Address forms used by characters contribute to the representation of social relations in the book. From the analysis of a few dialogs in the original text in English and their translations into Portuguese, this paper will discuss not only oral language indexes but also the ways how the choice of lexical items for addressing reveal different degrees of affectivity and social hierarchy. Some cases of loss in translation are registered as well as one case of domestication, in the terms of Venutti (1998.

  9. DE-MYTHOLOGIZING THE BARD: APPROPRIATION OF SHAKESPEARE IN TOM STOPPARD’S DOGG’S HAMLET, CAHOOT’S MACBETH

    Directory of Open Access Journals (Sweden)

    Ifeta Ciric-Fazlija

    2014-11-01

    Full Text Available One of the most entrenched myths that dramatic authors need to contest and adjust to is the Shakespeare myth, a long-lasting and all-pervasive influence that Shakespeare’s name and texts have exerted since the late 16th century, being perceived as “represent[ing] truths that transcend particular circumstances” (Sinfield, 1998: 129. In order to be actively involved in the “making of culture” (Sinfield, 1998: 128 and for the purpose of establishing and (redefining one’s own position within and against the canonical (transnational texts, many British dramatists, including Tom Stoppard, have alluded to, quoted, or incorporated portions of Shakespeare’s plays within their own, or even reconstituted them completely. This paper discusses the manner in which Stoppard appropriates Shakespeare’s Hamlet and Macbeth – probably his best known and most frequently staged and adapted tragedies – in order to question the importance of both the author and his work within the context of contemporary culture and society.

  10. Máscaras a la deriva: acerca de la narrativa de Tomás de Mattos

    Directory of Open Access Journals (Sweden)

    José Manuel González Álvarez

    2014-06-01

    Full Text Available El presente artículo pretende indagar en aspectos estructurales y temáticos de la novela La fragata de las máscaras (1996 del narrador uruguayo Tomás de Mattos. Tomando como punto de partida el Benito Cereno de Herman Melville, De Mattos construye un texto denso y laberíntico que no desmerece la prosa del escritor norteamericano. Aprovechando los cabos sueltos dejados por Melville en Benito Cereno, el uruguayo osa reescribir el episodio del motín acaecido pero invirtiendo las voces y dando protagonismo a los esclavos. Erige así una novela sugestiva en su planteamiento y compleja en su estructura, con un auténtico homenaje a la noción de transtextualidad en sentido lato, acuñada por Gérard Genette; intertextos, paratextos e hipertextos y continuas puestas en abismo se entrecruzan para conformar una novela polifónica pero no por ello estrictamente posmoderna, si nos atenemos al pensamiento del autor, muy distante del descreimiento que gobierna otros textos de la nueva novela histórica uruguaya coetáneos al que aquí analizamos.

  11. The effect of the Tom Thumb dwarfing gene on grain size and grain number of wheat (Triticum aestivum)

    International Nuclear Information System (INIS)

    Gale, M.D.; Flintham, J.E.

    1984-01-01

    The Tom Thumb dwarfing gene, Rht3, like the related genes Rht1 and Rht2 from Norin 10, has pleiotropic effects on individual ear yields, and grain protein concentrations. An experiment was conducted in which tiller number per plant and grain number per spike were restricted to ascertain whether reduced grain size and protein content are primary or secondary competitive effects in near-isogenic lines. The potential for grain growth was shown to be identical in Rht3 and rht genotypes when grain set was restricted, indicating that the primary effect of the gene is to increase spikelet fertility. Nitrogen accumulation within the grain was also affected by inter-grain competition but decreased nitrogen yields per plant indicated that reduced protein levels are, in part, a primary effect of the gene. Analysis of individual grain yields within Rht3 and rht spikes showed that the gene affected developmental 'dominance' relationships within the spike. (author)

  12. Analysis of Ozone (O3 and Erythemal UV (EUV measured by TOMS in the equatorial African belt

    Directory of Open Access Journals (Sweden)

    Øyvind Frette

    2010-03-01

    Full Text Available We presented time series of total ozone column amounts (TOCAs and erythemal UV (EUV doses derived from measurements by TOMS (Total Ozone Mapping Spectrometer instruments on board the Nimbus-7 (N7 and the Earth Probe (EP satellites for three locations within the equatorial African belt for the period 1979 to 2000. The locations were Dar-es-Salaam (6.8° S, 39.26° E in Tanzania, Kampala (0.19° N, 32.34° E in Uganda, and Serrekunda (13.28° N, 16.34° W in Gambia. Equatorial Africa has high levels of UV radiation, and because ozone shields UV radiation from reaching the Earth’s surface, there is a need to monitor TOCAs and EUV doses. In this paper we investigated the trend of TOCAs and EUV doses, the effects of annual and solar cycles on TOCAs, as well as the link between lightning and ozone production in the equatorial African belt. We also compared clear-sky simulated EUV doses with the corresponding EUV doses derived from TOMS measurements. The TOCAs were found to vary in the ranges 243 DU − 289 DU, 231 DU − 286 DU, and 236 DU − 296 DU, with mean values of 266.9 DU, 260.9 DU, and 267.8 DU for Dar-es-Salaam, Kampala and Serrekunda, respectively. Daily TOCA time series indicated that Kampala had the lowest TOCA values, which we attributed to the altitude effect. There were two annual ozone peaks in Dar-es-Salaam and Kampala, and one annual ozone peak in Serrekunda. The yearly TOCA averages showed an oscillation within a five-year period. We also found that the EUV doses were stable at all three locations for the period 1979−2000, and that Kampala and Dar-es-Salaam were mostly cloudy throughout the year, whereas Serrekunda was mostly free from clouds. It was also found that clouds were among the major factors determining the level of EUV reaching the Earth´s surface. Finally, we noted that during rainy seasons, horizontal advection effects augmented by lightning activity may be responsible for enhanced ozone production in the tropics.

  13. Changes in melatonin levels in transgenic 'Micro-Tom' tomato overexpressing ovine AANAT and ovine HIOMT genes.

    Science.gov (United States)

    Wang, Lin; Zhao, Yu; Reiter, Russel J; He, Changjiu; Liu, Guoshi; Lei, Qiong; Zuo, Bixiao; Zheng, Xiao Dong; Li, Qingtian; Kong, Jin

    2014-03-01

    In animals, the melatonin biosynthesis pathway has been well defined after the isolation and identification of the four key genes that are involved in the conversion of tryptophan to melatonin. In plants, there are special alternative catalyzing steps, and plant genes share very low homology with the animal genes. It was of interest to examine the phenotype of transgenic Micro-Tom tomato plants overexpressing the homologous sheep oAANAT and oHIOMT genes responsible for the last two steps of melatonin synthesis. The oAANAT transgenic plants have higher melatonin levels and lower indoleacetic acid (IAA) contents than control due to the competition for tryptophan, the same precursor for both melatonin and IAA. Therefore, the oAANAT lines lose the 'apical dominance' inferring that melatonin likely lacks auxin activity. The significantly higher melatonin content in oHIOMT lines than oAANAT lines provides new proof for the important role of ASMT in plant melatonin synthesis. In addition, the enhanced drought tolerance of oHIOMT lines will also be an important contribution for plant engineering. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  14. The Song of the Sabia in the 3rd. Festival Internacional da Canção: boo and sunset of the Tom Jobim bossa nova`s aesthetics

    Directory of Open Access Journals (Sweden)

    Fabio Guilherme Poletto

    2015-07-01

    Full Text Available This article discusses the Song of the Sabia, composition of Tom Jobim and Chico Buarque. Mobilizes different series of sources in order to reconstruct historically the boo to the performance of the song during the III International Song Festival, held in 1968 in the city of Rio de Janeiro. Seeks to highlight how this episode catalyzed the existence of different expectations on the popular song and its role as a vehicle for ideals of modernity amid the interference of the authoritarian environment in the cultural and political field. Then, based on the analysis of the constitutive parameters of the song, suggests possibilities for understanding its musical and poetic construction in critical dialogue with its reverberations in cultural terms.This article discusses the Song of the Sabia, composition of Tom Jobim and Chico Buarque. Mobilizes different series of sources in order to reconstruct historically the boo to the performance of the song during the III International Song Festival, held in 1968 in the city of Rio de Janeiro. Seeks to highlight how this episode catalyzed the existence of different expectations on the popular song and its role as a vehicle for ideals of modernity amid the interference of the authoritarian environment in the cultural and political field. Then, based on the analysis of the constitutive parameters of the song, suggests possibilities for understanding its musical and poetic construction in critical dialogue with its reverberations in cultural terms.

  15. 5-7 Year Old Children's Conceptions of Behaving Artifacts and the Influence of Constructing Their Behavior on the Development of Theory of Mind (ToM and Theory of Artificial Mind (ToAM

    Directory of Open Access Journals (Sweden)

    Karen Spektor-Precel

    2015-12-01

    Full Text Available Nowadays, we are surrounded by artifacts that are capable of adaptive behavior, such as electric pots, boiler timers, automatic doors, and robots. The literature concerning human beings’ conceptions of “traditional” artifacts is vast, however, little is known about our conceptions of behaving artifacts, nor of the influence of the interaction with such artifacts on cognitive development, especially among children. Since these artifacts are provided with an artificial “mind,” it is of interest to assess whether and how children develop a Theory of Artificial Mind (ToAM which is distinct from their Theory of Mind (ToM. The study examined a new theoretical scheme named ToAM (Theory of Artificial Mind by means of qualitative and quantitative methodology among twenty four 5-7 year old children from central Israel. It also examined the effects of interacting with behaving artifacts (constructing versus observing the robot’s behavior using the “RoboGan” interface on children’s development of ToAM and their ToM and looked for conceptions that evolve among children while interacting with behaving artifacts which are indicative of the acquisition of ToAM. In the quantitative analysis it was found that the interaction with behaving artifacts, whether as observers or constructors and for both age groups, brought into awareness children’s ToM as well as influenced their ability to understand that robots can behave independently and based on external and environmental conditions. In the qualitative analysis it was found that participating in the intervention influenced the children’s ToAM for both constructors and for the younger observer. Engaging in building the robot’s behavior influenced the children’s ability to explain several of the robots’ behaviors, their understanding of the robot’s script-based behavior and rule-based behavior and the children’s metacognitive development. The theoretical and practical importance of

  16. A comparison of cervical smear adequacy using either the cytobrush ...

    African Journals Online (AJOL)

    A comparison of cervical smear adequacy using either the cytobrush or the Ayre spatula: a practice audit. ... The purpose of this study was to compare the adequacy of cervical smears taken with the Ayre spatula as opposed to the cytobrush. Methods: This was a retrospective analytical study. One sampler, an experienced ...

  17. Azo dye removal in a membrane-free up-flow biocatalyzed electrolysis reactor coupled with an aerobic bio-contact oxidation reactor

    International Nuclear Information System (INIS)

    Cui, Dan; Guo, Yu-Qi; Cheng, Hao-Yi; Liang, Bin; Kong, Fan-Ying; Lee, Hyung-Sool; Wang, Ai-Jie

    2012-01-01

    Highlights: ► A membrane-free up-flow biocatalyzed electrolysis reactor coupled with an aerobic bio-contact oxidation reactor was developed. ► Alizarin Yellow R as the mode of azo dyes was efficiently converted to p-phenylenediamine (PPD) and 5-aminosalicylic acid (5-ASA). ► PPD and 5-ASA were further oxidized in a bio-contact oxidation reactor. ► The mechanism of UBER for azo dye removal was discussed. - Abstract: Azo dyes that consist of a large quantity of dye wastewater are toxic and persistent to biodegradation, while they should be removed before being discharged to water body. In this study, Alizarin Yellow R (AYR) as a model azo dye was decolorized in a combined bio-system of membrane-free, continuous up-flow bio-catalyzed electrolysis reactor (UBER) and subsequent aerobic bio-contact oxidation reactor (ABOR). With the supply of external power source 0.5 V in the UBER, AYR decolorization efficiency increased up to 94.8 ± 1.5%. Products formation efficiencies of p-phenylenediamine (PPD) and 5-aminosalicylic acid (5-ASA) were above 90% and 60%, respectively. Electron recovery efficiency based on AYR removal in cathode zone was nearly 100% at HRTs longer than 6 h. Relatively high concentration of AYR accumulated at higher AYR loading rates (>780 g m −3 d −1 ) likely inhibited acetate oxidation of anode-respiring bacteria on the anode, which decreased current density in the UBER; optimal AYR loading rate for the UBER was 680 g m −3 d −1 (HRT 2.5 h). The subsequent ABOR further improved effluent quality. Overall the Chroma decreased from 320 times to 80 times in the combined bio-system to meet the textile wastewater discharge standard II in China.

  18. Azo dye removal in a membrane-free up-flow biocatalyzed electrolysis reactor coupled with an aerobic bio-contact oxidation reactor

    Energy Technology Data Exchange (ETDEWEB)

    Cui, Dan; Guo, Yu-Qi; Cheng, Hao-Yi; Liang, Bin; Kong, Fan-Ying [State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, No. 202 Haihe Road, Harbin 150090 (China); Lee, Hyung-Sool [Department of Civil and Environmental Engineering, University of Waterloo, 200 University Avenue West Waterloo, Ontario, Canada N2L 3G1 (Canada); Wang, Ai-Jie, E-mail: waj0578@hit.edu.cn [State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, No. 202 Haihe Road, Harbin 150090 (China)

    2012-11-15

    Highlights: Black-Right-Pointing-Pointer A membrane-free up-flow biocatalyzed electrolysis reactor coupled with an aerobic bio-contact oxidation reactor was developed. Black-Right-Pointing-Pointer Alizarin Yellow R as the mode of azo dyes was efficiently converted to p-phenylenediamine (PPD) and 5-aminosalicylic acid (5-ASA). Black-Right-Pointing-Pointer PPD and 5-ASA were further oxidized in a bio-contact oxidation reactor. Black-Right-Pointing-Pointer The mechanism of UBER for azo dye removal was discussed. - Abstract: Azo dyes that consist of a large quantity of dye wastewater are toxic and persistent to biodegradation, while they should be removed before being discharged to water body. In this study, Alizarin Yellow R (AYR) as a model azo dye was decolorized in a combined bio-system of membrane-free, continuous up-flow bio-catalyzed electrolysis reactor (UBER) and subsequent aerobic bio-contact oxidation reactor (ABOR). With the supply of external power source 0.5 V in the UBER, AYR decolorization efficiency increased up to 94.8 {+-} 1.5%. Products formation efficiencies of p-phenylenediamine (PPD) and 5-aminosalicylic acid (5-ASA) were above 90% and 60%, respectively. Electron recovery efficiency based on AYR removal in cathode zone was nearly 100% at HRTs longer than 6 h. Relatively high concentration of AYR accumulated at higher AYR loading rates (>780 g m{sup -3} d{sup -1}) likely inhibited acetate oxidation of anode-respiring bacteria on the anode, which decreased current density in the UBER; optimal AYR loading rate for the UBER was 680 g m{sup -3} d{sup -1} (HRT 2.5 h). The subsequent ABOR further improved effluent quality. Overall the Chroma decreased from 320 times to 80 times in the combined bio-system to meet the textile wastewater discharge standard II in China.

  19. Analysis of cohesive devices in a short text: 'Whiskey. No water. No ice.' by Tom Hart

    Directory of Open Access Journals (Sweden)

    Janković Anita V.

    2017-01-01

    Full Text Available The aim of this paper was two-fold. Primarily, based on literature review, it presented various takes on what constitutes a text and what makes it cohesive. Secondly, it reported the results of the cohesion analysis performed on a short drama by Tom Hart. This drama was written as a submission for the London Royal Court Theatre competition '100 Word Play'. The author used the model of analysis of a dramatic dialogue proposed by Halliday and Hassan. The dramatic dialogue here is characterized as a speaking text, for the stage; therefore, the stage directions were excluded from the analysis as para-linguistic phenomena. The results of the analysis revealed immediate ellipsis of anaphoric direction as the most common cohesive device in 47 percent of the text. Second in frequency are referencing mechanisms, and finally lexical devices and connectors. Furthermore, the analysis exposed the use of reiteration, both lexical and structural, which is not predicted by the model. However, these instances were explained by Hoey's model of lexical repetition. The thematic progression in the text is linear which is characteristic of dialogues. The analysis noted no usage of substitution nor parallelism, which is in itself indicative of the set hypothesis because parallelisms are characteristic of poetry and political discourse.

  20. Presentación clínica de tuberculosis en pacientes VIH+ atendidos en el Hospital Santo Tomás, Panamá. Enero a julio del 2009

    Directory of Open Access Journals (Sweden)

    Bernardino Denis

    2010-01-01

    Full Text Available Objetivo: describir las presentaciones clínicas de la tuberculosis en los pacientes VIH+ atendidos en el Hospital Santo Tomás de enero a julio de 2009. Metodología: se trata de un estudio descriptivo retrospectivo que consistió en la revisión de expedientes clínicos de los pacientes que presentaron coinfección de tuberculosis y VIH en el Hospital Santo Tomás durante el primer semestre del año 2009. Se analizó el universo de pacientes. Se utilizó un formulario para la recolección de los datos y para el análisis de los datos se calcularon frecuencias, modas, medianas y promedios. Se utilizo el programa EpiInfo 3.5.1 y se realizaron los gráficos con Microsoft Office Excel. Resultados: La relación hombres : mujeres fue de 3 : 1. Se observó una mayor frecuencia de pacientes procedentes del corregimiento de Juan Díaz (13,5% Calidonia (10,4% Santa Ana (10,4%. La presentación clínica predominante fue la pulmonar (64,4% seguida por la mixta (20% y la extrapulmonar (15,6%; entre las formas extrapulmonares la más frecuente fue la ganglionar (37,5%. Conclusiones: La presentación clínica pulmonar reporta es de 64,4%; extrapulmonar, 15,6%; y mixta, 20,0%. Entre las presentaciones extrapulmonares, la presentación ganglionar se reporta en 37,5%. El método clínico radiológico es el medio diagnóstico más usado (76% a diferencia de otros estudios.

  1. Teenage pregnancy - a study in São Tomé and Príncipe.

    Science.gov (United States)

    Carvalho, Fábia; Medeiros, Inês de; Faria, Catarina; Cotu, Djamilla; Will, Endza Paula; Neves, Edgar; Pontes, Teresa

    2017-08-22

    Introduction The increasing number of pregnant teenagers in São Tomé and Príncipe (STP) represents a serious public health issue. The aim of this study was to characterize the population of pregnant adolescents followed in a health facility dedicated to maternal health in STP. Methods A cross-sectional survey was conducted among pregnant teenagers that attended the Mother and Child Protection Center during the first quarter of 2017. The survey contained questions on sociodemographic characteristics, sexual and risk behaviors, family, partners and health support. Results The mean age of the 51 pregnant teenagers included was 16.37 ± 0.8 years. Eight girls reported that they had planned to fall pregnant. Teenagers whose pregnancy was unplanned usually present with a previous family history of adolescent pregnancy. About 59% of girls engaged in sexual activity before 16 years of age with a mean number of sexual partners of 1.84 ± 0.88. In this study, 51% of the girls do not use any contraceptive method, usually because their partner refuses to do so. The preferred contraceptive method are condoms. Information on contraception is given mainly at school. Pregnant girls' first medical consultation was at a mean gestational age of 6 weeks. Abortion was considered by 51% of girls after pregnancy was confirmed. Conclusion Teenage pregnancy imposes health problems for the mother and child and contributes to educational and socioeconomic disadvantages. The collaboration of healthcare providers, teachers and parents is needed to enhance sexual health education. This is the first study in STP on teenage pregnancy; although the sample is small, the authors believe that the results are representative of the general population.

  2. Biogeochemical migration of heavy metals, Ti, V, Mo, Ta, W, and U, in the profile of a low-laid peatbog in the country between the Ob and Tom rivers

    International Nuclear Information System (INIS)

    Efremova, T.T.; Efremov, S.P.; Koutsenogii, K.P.; Peresedov, V.F.

    2003-01-01

    Biogeochemical migration of heavy metals in the course of marsh formation is mainly determined by physical-chemical processes, such as the oxidation-reduction zonality of the peatbog thickness and the state of humous substances (the quality of humus adsorptive barriers). In the process of peatbog formation V, U, Ta are the weakly captured elements while Mo is captured to a relatively higher extent. Elements as Ti and W are found in separate layers. No technogenic degradation of the marsh ecosystem in the Ob and Tom has been observed. (author)

  3. Wave activity (planetary, tidal throughout the middle atmosphere (20-100km over the CUJO network: Satellite (TOMS and Medium Frequency (MF radar observations

    Directory of Open Access Journals (Sweden)

    A. H. Manson

    2005-02-01

    Full Text Available Planetary and tidal wave activity in the tropopause-lower stratosphere and mesosphere-lower thermosphere (MLT is studied using combinations of ground-based (GB and satellite instruments (2000-2002. The relatively new MFR (medium frequency radar at Platteville (40° N, 105° W has provided the opportunity to create an operational network of middle-latitude MFRs, stretching from 81° W-142° E, which provides winds and tides 70-100km. CUJO (Canada U.S. Japan Opportunity comprises systems at London (43° N, 81° W, Platteville (40° N, 105° W, Saskatoon (52° N, 107° W, Wakkanai (45° N, 142° E and Yamagawa (31° N, 131° E. It offers a significant 7000-km longitudinal sector in the North American-Pacific region, and a useful range of latitudes (12-14° at two longitudes. Satellite data mainly involve the daily values of the total ozone column measured by the Earth Probe (EP TOMS (Total Ozone Mapping Spectrometer and provide a measure of tropopause-lower stratospheric planetary wave activity, as well as ozone variability. Climatologies of ozone and winds/tides involving frequency versus time (wavelet contour plots for periods from 2-d to 30-d and the interval from mid 2000 to 2002, show that the changes with altitude, longitude and latitude are very significant and distinctive. Geometric-mean wavelets for the region of the 40° N MFRs demonstrate occasions during the autumn, winter and spring months when there are similarities in the spectral features of the lower atmosphere and at mesopause (85km heights. Both direct planetary wave (PW propagation into the MLT, nonlinear PW-tide interactions, and disturbances in MLT tides associated with fluctuations in the ozone forcing are considered to be possible coupling processes. The complex horizontal wave numbers of the longer period oscillations are provided in frequency contour plots for the TOMS satellite data to demonstrate the differences between lower atmospheric and MLT wave motions and their

  4. Wave activity (planetary, tidal) throughout the middle atmosphere (20-100km) over the CUJO network: Satellite (TOMS) and Medium Frequency (MF) radar observations

    Science.gov (United States)

    Manson, A. H.; Meek, C. E.; Chshyolkova, T.; Avery, S. K.; Thorsen, D.; MacDougall, J. W.; Hocking, W.; Murayama, Y.; Igarashi, K.

    2005-02-01

    Planetary and tidal wave activity in the tropopause-lower stratosphere and mesosphere-lower thermosphere (MLT) is studied using combinations of ground-based (GB) and satellite instruments (2000-2002). The relatively new MFR (medium frequency radar) at Platteville (40° N, 105° W) has provided the opportunity to create an operational network of middle-latitude MFRs, stretching from 81° W-142° E, which provides winds and tides 70-100km. CUJO (Canada U.S. Japan Opportunity) comprises systems at London (43° N, 81° W), Platteville (40° N, 105° W), Saskatoon (52° N, 107° W), Wakkanai (45° N, 142° E) and Yamagawa (31° N, 131° E). It offers a significant 7000-km longitudinal sector in the North American-Pacific region, and a useful range of latitudes (12-14°) at two longitudes. Satellite data mainly involve the daily values of the total ozone column measured by the Earth Probe (EP) TOMS (Total Ozone Mapping Spectrometer) and provide a measure of tropopause-lower stratospheric planetary wave activity, as well as ozone variability. Climatologies of ozone and winds/tides involving frequency versus time (wavelet) contour plots for periods from 2-d to 30-d and the interval from mid 2000 to 2002, show that the changes with altitude, longitude and latitude are very significant and distinctive. Geometric-mean wavelets for the region of the 40° N MFRs demonstrate occasions during the autumn, winter and spring months when there are similarities in the spectral features of the lower atmosphere and at mesopause (85km) heights. Both direct planetary wave (PW) propagation into the MLT, nonlinear PW-tide interactions, and disturbances in MLT tides associated with fluctuations in the ozone forcing are considered to be possible coupling processes. The complex horizontal wave numbers of the longer period oscillations are provided in frequency contour plots for the TOMS satellite data to demonstrate the differences between lower atmospheric and MLT wave motions and their

  5. Wave activity (planetary, tidal throughout the middle atmosphere (20-100km over the CUJO network: Satellite (TOMS and Medium Frequency (MF radar observations

    Directory of Open Access Journals (Sweden)

    A. H. Manson

    2005-02-01

    Full Text Available Planetary and tidal wave activity in the tropopause-lower stratosphere and mesosphere-lower thermosphere (MLT is studied using combinations of ground-based (GB and satellite instruments (2000-2002. The relatively new MFR (medium frequency radar at Platteville (40° N, 105° W has provided the opportunity to create an operational network of middle-latitude MFRs, stretching from 81° W-142° E, which provides winds and tides 70-100km. CUJO (Canada U.S. Japan Opportunity comprises systems at London (43° N, 81° W, Platteville (40° N, 105° W, Saskatoon (52° N, 107° W, Wakkanai (45° N, 142° E and Yamagawa (31° N, 131° E. It offers a significant 7000-km longitudinal sector in the North American-Pacific region, and a useful range of latitudes (12-14° at two longitudes. Satellite data mainly involve the daily values of the total ozone column measured by the Earth Probe (EP TOMS (Total Ozone Mapping Spectrometer and provide a measure of tropopause-lower stratospheric planetary wave activity, as well as ozone variability.

    Climatologies of ozone and winds/tides involving frequency versus time (wavelet contour plots for periods from 2-d to 30-d and the interval from mid 2000 to 2002, show that the changes with altitude, longitude and latitude are very significant and distinctive. Geometric-mean wavelets for the region of the 40° N MFRs demonstrate occasions during the autumn, winter and spring months when there are similarities in the spectral features of the lower atmosphere and at mesopause (85km heights. Both direct planetary wave (PW propagation into the MLT, nonlinear PW-tide interactions, and disturbances in MLT tides associated with fluctuations in the ozone forcing are considered to be possible coupling processes. The complex horizontal wave numbers of the longer period oscillations are provided in frequency contour plots for the TOMS satellite data to demonstrate the differences between lower atmospheric

  6. Caracterización del perfil de los estudiantes de Negocios Internacionales de la Universidad Santo Tomás, sede Bogotá

    Directory of Open Access Journals (Sweden)

    Myriam Soraya Suárez R.

    2013-01-01

    Full Text Available Los estudios sobre el perfil de los estudiantes universitarios se han llevado a cabo permanentemente, debido a que las universidades requieren saber con qué estudiantes cuentan y cómo estos requieren ser formados, de acuerdo con las necesidades actua - les del mercado laboral y las necesidades sociales del contexto en el cual se encuentran inmersos. Esta investigación sobre la caracterización del perfil de los estudiantes de la Facultad de Negocios Internacionales de la Universidad Santo Tomás, sede Bogotá, determinó los aspectos biográficos, sociodemográficos, proyecto de vida, perfil educativo y profesional, competencias y uso del tiempo libre, con el fin de describir las motivaciones, intereses y percepciones, lo cual permitió tener un conocimiento holístico de los estudiantes y de todos los aspectos involucrados en su formación.

  7. Interakce mediálního a marketingového diskurzu na příkladu mediálního obrazu hudebníka Tomáše Kluse

    OpenAIRE

    Nováková, Kristýna

    2011-01-01

    This diploma thesis Interaction of media and marketing discourse on the media image of musician Tomáš Klus examines the influence of the corporate agenda through the marketing and PR department of a record label Sony Music Entertainment Czech Republic s.r.o. on the agenda of the media, which represent the work of three full-scale Czech newspaper MF Dnes, Právo a Blesk. The theoretical approach is being built on the basic theses of media construction of reality and construction of media image,...

  8. Ecologization of water-land property matters on the territory of the Tom lower course

    Science.gov (United States)

    Popov, V. K.; Kozina, M. V.; Levak, Yu Yu; Shvagrukova, E. V.

    2016-03-01

    In the present paper the water-land property complex is considered as a strategic resource of the city development. The formulated question is expounded through the example of water-land property complex usage on the territory of the Tom lower course for land-use planning and developing the systems of water recourses management and land tenure. Consequences of liquid radioactive waste (LRW) landfilling are investigated in terms of arable farming. Also, forming a water budget of the soils spread on the area of the Tomsk underground water supply cone of depression and its role in the development of agricultural industry are studied. The main aspect of the analysis is the incorporation of social, economic, and ecological requirements for the system of life-supporting branches of municipal economy and social services. As far as the system of land tax payments plays an important role in land property complex management, the common issues and tendencies are specified in the paper. These problems are concerned with the inadequate incorporation of an ecological constituent in the methods of cadastral valuation of lands, as well as the situation of the narrow area of its results usage in the Russian Federation. Natural factors (hydrological, territorial, geological (geomorphologic) territory conditions) are combined by the authors into a special group. These factors should be reflected in the results of cadastral valuation. Also, in order to protect the interests of water consumers, it is offered to establish the Water Consumers Association based on the international experience of such countries as Spain and Uzbekistan.

  9. The Rg1 allele as a valuable tool for genetic transformation of the tomato 'Micro-Tom' model system

    Directory of Open Access Journals (Sweden)

    Quecini Vera

    2010-10-01

    Full Text Available Abstract Background The cultivar Micro-Tom (MT is regarded as a model system for tomato genetics due to its short life cycle and miniature size. However, efforts to improve tomato genetic transformation have led to protocols dependent on the costly hormone zeatin, combined with an excessive number of steps. Results Here we report the development of a MT near-isogenic genotype harboring the allele Rg1 (MT-Rg1, which greatly improves tomato in vitro regeneration. Regeneration was further improved in MT by including a two-day incubation of cotyledonary explants onto medium containing 0.4 μM 1-naphthaleneacetic acid (NAA before cytokinin treatment. Both strategies allowed the use of 5 μM 6-benzylaminopurine (BAP, a cytokinin 100 times less expensive than zeatin. The use of MT-Rg1 and NAA pre-incubation, followed by BAP regeneration, resulted in high transformation frequencies (near 40%, in a shorter protocol with fewer steps, spanning approximately 40 days from Agrobacterium infection to transgenic plant acclimatization. Conclusions The genetic resource and the protocol presented here represent invaluable tools for routine gene expression manipulation and high throughput functional genomics by insertional mutagenesis in tomato.

  10. Identification of multiple PEPC isogenes in leaves of the facultative Crassulacean acid metabolism (CAM) plant Kalanchoe blossfeldiana Poelln. cv. Tom Thumb.

    Science.gov (United States)

    Gehrig, H; Taybi, T; Kluge, M; Brulfert, J

    1995-12-27

    In the facultative Crassulacean Acid Metabolism (CAM) plant Kulanchoe blossfeldiana cv. Tom Thumb, CAM can be induced by short-day treatment or water deficiency stress. From young leaves of well-watered and water-stressed individuals of this plant, cDNA clones coding for a partial sequence of the key enzyme of CAM, phosphoenolpyruvate carboxylase, were isolated after transcription of mRNA. cDNA polymorphism was established by enzyme restriction profiles and sequencing data. Four PEPC isogenes could be shown to exist in K. blossfeldiana forming two gene pairs, with 95%-98% homology inside and only 75% between the pairs. One cDNA sequence pair having a length of 1113 bp and an open reading frame of 371 AA was identified as PEPC isoform specific for the C3 state, whereas the pair having a length of 1116 bp and an open reading frame of 372 AA could be attributed to the CAM state. These results were confirmed by Southern Blot hybridization.

  11. The Former Miss Barstow with every Tom, Dick and Harry in a doll's house

    Directory of Open Access Journals (Sweden)

    Richard Newton

    2015-02-01

    Full Text Available Julie Holledge, panel chairperson and member of the International Ibsen Committee, invited myself along with 3 others to participate in the Inaugural Artists’ Keynote Panel: Applied Ibsen on Four Continents: The Artists’ Intentions. My presentation focused on “The Former Miss Barstow with every Tom, Dick and Harry in a doll’s house.” This was an adaptation of Ibsen’s “A Doll’s House” produced and staged in Los Angeles, California, 1987.  For the XIIIth International Ibsen Conference at the University of Tromsø, Norway, I projected images; a few found on the internet, and many from the production itself, as well as a video clip shown streaming live from YouTube. The article describes the social context of the 80s, analyzes the reinterpretation of Ibsen’s characters, and sets out to explain the symbology of the sets and costumes. I also touch on the differences between this production and Ibsen’s original in four important aspects. These would be the macaroons, the Tarantella, the silk stockings and the end of the play. Finally, I explain my decision to upload this version of “A Doll’s House,’ scene by scene, to my page on YouTube. Having shown films and videos for many years at festivals around the globe, I was looking for a way to step outside that box and reach an international audience just beyond my keyboard. In all of these ways, the goal has been to illuminate the ways in which an artist takes Ibsen’s text and applies it to the specific social context of their time and culture.

  12. L’Epítome de Llorenç Tomàs, canceller del Principat de Catalunya (1705-1714). Un document fins ara desconegut sobre els precedents de la Guerra de Successió

    OpenAIRE

    Ballbé i Sans, Neus

    2006-01-01

    Estudi centrat en l’epítom escrit pel canceller de Catalunya durant el govern de Carles III i que explica, en primera persona, els fets esdevinguts a la plana de Vic abans de l’arribada de l’Arxiduc el 1705. Estudio centrado en el epítome escrito por el canciller de Cataluña durante el gobierno de Carlos III y que explica, en primera persona, los hechos ocurridos en el llano de Vic antes de la llegada del Archiduque en 1705. Study centered on the written epitome by the chancellor of Cat...

  13. As inovações de Tom Zé na linguagem da canção popular dos anos 1970

    Directory of Open Access Journals (Sweden)

    Herom Vargas

    2012-12-01

    Full Text Available O objetivo deste artigo é discutir alguns aspectos da experimentação do compositor brasileiro Tom Zé em três de seus cinco discos lançados nos anos 1970, dentro de um cenário de exceção institucional por conta da ditadura militar e de expansão das indústrias culturais. Do cantor, serão tratadas canções dos discos: Se o caso é chorar (Continental - 1972, Todos os olhos (Continental - 1973 e Estudando o samba (Continental - 1975. A noção básica de experimentação utilizada é de Umberto Eco (1970. Outro conceito para a discussão do experimentalismo é o de “canção crítica”, desenvolvido por S.C. Naves (2010. Como horizonte teórico, a canção popular será tratada como “texto semiótico”, conforme a semiótica da cultura de I.M. Lótman (1996. Os aspectos de inovação serão analisados internamente à própria linguagem híbrida da canção (letra, canto, música e performance e nas relações externas entre canção e contexto cultural.

  14. Contribuição ao estudo da circulação e do transporte de volume da corrente do Brasil entre o Cabo de São Tomé e a Baía de Guanabara Contribution to the studies of transport and circulation of the Brazil current in the are a between Cabo de São Tomé and Guanabara Bay

    Directory of Open Access Journals (Sweden)

    Sérgio R Signorini

    1976-01-01

    Full Text Available Tal estudo teve por finalidade avaliar a velocidade e o transporte de volume da Corrente do Brasil, no seu trecho entre Cabo de São Tomé e Cabo Frio, fazendo uso do calculo geostrofico aplicado às secções amostradas durante os cruzeiros de abril e julho de 1970 e de julho de 1973. Foram localizados dois vórtices anticiclônicos, um durante o período de abril de 1970 e o outro durante julho de 1973. O valor máximo de velocidade da corrente na superfície foi de aproximadamente 70 cm/s e o transporte de volume foi de 14 x 10(6 m³/s. Foi possível também confirmar a existência de um meandro da Corrente do Brasil através da utilização de uma secção de BT (batitermografo mecânico associada a um registro contínuo de salinidade e de temperatura obtido com um termosalinografo.During the periods of April, July, 1970 and July, 1973, océanographic cruises were conducted in order to investigate the variability of the Brazil Current in the region between Cabo de Sao Tomé and Guanabara Bay. The geostrophic model of ocean circulation was applied using the hydrographie data collected during the cruise. From this study, a maximum velocity of 70 cm/sec and a volume trans port of 14 x 10(6 m³/sec were reported. The dynamic topography with reference to the 500 db surface, showed the presence of anticyclonic eddies during the periods of April, 1970, and July, 1973. The thermohaline structure within a meander of the Brazil Current is also presented utilizing the data coming from a continuous salinity and temperature recorder in conection with the data coming from a simultaneous BT section.

  15. Emergencia de la conciencia intelectiva. La teoría creacionista según Tomás de Aquino

    Directory of Open Access Journals (Sweden)

    Lorenzo Vicente Burgoa

    2016-10-01

    Full Text Available La pregunta «¿de dónde venimos?" sigue siendo de interés, para saber qué somos y hacia dónde vamos ... Una vez aceptada la evolución transespecífica de los seres vivos, actualmente todos o casi todos aceptan el origen filogenético del cuerpo humano. Pero hay notables reticencias y hasta serias dificultades para aceptar ese mismo origen para el alma humana. Esas dificultades provienen tanto de un supuesto dogma acerca de la creación del alma directamente por Dios, como de posiciones metafísicas muy serias, entre las que cabe destacar la argumentación de Tomás de Aquino. El autor de este trabajo, dejando de lado el aspecto teológico -aunque señalando de paso su duda fundada respecto de la existencia de tal dogma creacionista- se enfrenta a los argumentos metafísicos, desde las mismas bases sistemáticas en que tales argumentos parecen fundarse. Su conclusión es que esos argumentos no son decisivos; y que, por tanto, se puede y se debe seguir buscando un origen filogenético común para el hombre en su totalidad, dejando de lado el dualismo antropológico accidentalista, de tipo platónico y racionalista.

  16. La ratio legis en la teología de Suarez y Santo Tomás: Una propuesta de comparación

    Directory of Open Access Journals (Sweden)

    Sebastián Contreras

    2012-01-01

    Full Text Available El presente trabajo intenta profundizar en las nociones de ley de dos de los más importantes teólogos escolásticos:Tomás de Aquino y Francisco Suárez. Sabemos que el Eximio pretende dar sentido e inteligencia a las palabras del Aquinatense. Usualmente se ha marcado el voluntarismo y distancia que toma Suárez con respecto a la teologia del Maestro Angélico, motivo por el cual hemos querido bosquejar una posible continuidad entre ambos doctores de la teologia escolástica: todo a partir del análisis del concepto de imperium.This paper tries deeper into the notions of law of two of the most important scholastics: Aquinas and Suarez. We know that Suarez tries give sense and intelligence at the Aquinas' words. Usually we mark the voluntarism and the distance that Suarez takes over the Aquinas' theology; for this we wanted outline a possible continuity between the two doctors of scholastic theology: everything from the analysis of the concept of imperium.

  17. Brad Patterson, Tom Brooking, and Jim McAloon, Unpacking the Kist: The Scots in New Zealand. McGill-Queen's Studies in Ethnic History Series, No. 2.33. Montreal: McGill-Queen’s University Press, 2013. Pp. 412. ISBN 978-0-7735-4190-0. CAD $100.00.

    Directory of Open Access Journals (Sweden)

    Seán Gerard Brosnahan

    2014-11-01

    Full Text Available Brad Patterson, Tom Brooking, and Jim McAloon, Unpacking the Kist: The Scots in New Zealand. McGill-Queen's Studies in Ethnic History Series, No. 2.33. Montreal: McGill-Queen’s University Press, 2013. Pp. 412. ISBN 978-0-7735-4190-0. CAD $100.00.

  18. Acute and chronic malnutrition and their predictors in children aged 0-5 years in São Tomé: a cross-sectional, population-based study.

    Science.gov (United States)

    Valente, A; Silva, D; Neves, E; Almeida, F; Cruz, J L; Dias, C C; da Costa-Pereira, A; Caldas-Afonso, A; Guerra, A

    2016-11-01

    Undernutrition is an important cause of morbidity and mortality in infants and children worldwide. The aim of this study was to evaluate the nutritional status and their predictors in children from 0 to 5 years of age in São Tomé. A cross-sectional study was conducted in São Tomé Island. A total of 1285 individuals were enrolled between January and May 2011. Children were measured, and height for age (HAZ), weight for height (WHZ) and body mass index (BAZ) Z-score were computed. Global acute undernutrition is defined as weight for height health bulletins, namely gestational age and birth weight, as well as weight at 6, 12, 18 and 24 months for all individual above these ages. Mothers were invited to answer a specific questionnaire. A high percentage of global acute undernutrition (30.9% in 12 months. Weight gain above 0.67 Z-score in the first semester of life was strongly related to lower odds for both acute (OR 0.109 [95% CI 0.040-0.291]) and chronic undernutrition (OR 0.379 [95% CI 0.187-0.770]) in children >12 months of age. Similarly, mother's education seems to protect against acute (>12 months: OR 0.448 [95% CI 0.244-0.825]; >24 months: OR 0.186 [95% CI 0.064-0.540]) and chronic undernutrition (>12 months: OR 0.389 [95% CI 0.232-0.653]; >24 months: OR 0.324 [95% CI 0.171-0.625]). All logistic regressions were adjusted for all children (gender, age, gestational age, birth weight, breastfeeding, begin consumption alcohol), mothers (age, height, body mass index, educational level, number of previous pregnancies, smoking during pregnancy, alcohol consumption during pregnancy) and household (number of siblings and persons at home) variables included in the protocol. Birth weight, nutritional status, and the mother's education and weight gain particularly in the first year of life were important factors protecting against undernutrition during infancy and childhood. These results emphasize the importance of women's nutrition and of adequate birth weight and

  19. Os inconfidentes nas Minas Gerais: uma relação entre a Geografia e a Literatura Setecentista de Cláudio Manuel da Costa, Tomás Antônio Gonzaga e Alvarenga Peixoto

    OpenAIRE

    Araújo, Kárita de Fátima

    2014-01-01

    Objetivando compreender a maneira pela qual se processou a construção da identidade nacional e da formação territorial brasileira no contexto das Minas Gerais setecentistas, procuramos fazê-lo à luz das obras literárias dos poetas inconfidentes. Para tal, escolhemos Vila Rica de Cláudio Manuel da Costa; Cartas chilenas de Tomás Antônio Gonzaga e, Canto Genetlíaco de Inácio José de Alvarenga Peixoto. Ao trabalhar no entrecruzamento da Geografia com a Literatura, buscamos aliar a...

  20. Nükleer Yakıt Zenginleştirme İşleminde Kullanılan Gaz Santrifüj Yönteminin İncelenmesi

    Directory of Open Access Journals (Sweden)

    Seyit Rıza TOKGÖZ

    2017-02-01

    Full Text Available Özet. Nükleer teknolojiye sahip olmak, günümüz ülkelerinin gelişmişliğinin bir ölçüsü olup, bu çalışmada nükleer reaktörlerde kullanılan yakıtın santrifüj yöntemi ile zenginleştirilmesi incelenmiştir. Santrifüj metodunda ayrıştırma faktörünün hesaplanması, farklı tip santrifüjler’ in ayrıştırma iş birimlerinin bulunması ve bunların performanslarının karşılaştırılması yapılmıştır.Anahtar Kelimeler: Nükleer teknoloji; Santrifüj metodu; Ayrıştırma faktörü; Ayrıştırma iş birimi(SWU Abstract. Having nuclear technology is a measure of the development of present-day countries. In this study, the enrichment process of fuel used in nuclear reactors by centrifugation method has been investigated. The centrifugation method has been used to calculate the separation factor, to find the separation units of different types of centrifuges, and their performance has been compared.Keywords: Nuclear technology, Centrifuge method, Separation factor, Separation work unit (SWU

  1. Arquitectura, urbanismo y obras públicas civiles y militares en el Atlas Geográfico de España de Tomás López de 1804

    Directory of Open Access Journals (Sweden)

    San-Antonio-Gómez, C.

    2016-06-01

    Full Text Available This manuscript presents a novel analysis that deals about how architecture, urban planning and civil and military public works are represented in Geographic Atlas of Spain 1804 (AGE of Tomas Lopez. For this it has been characterized different map symbols appearing on maps, which are the benchmarks for analysis and transmit accurate information on the shape and meaning of what is represented. So, more than one hundred different symbols were found. This gives an idea of the great detail and richness of the information contained in AGE. A deeper analysis shows that eighteen of them are equivalent to other previous cartographic symbols. These were from Chevalier, D’Anville teacher, who in turn was the teacher Thomas Lopez in Paris. Additionally, we found that there are several symbols with similarity to their corresponding of the Ordinances of the Royal Corps of Engineers from 1803.El objetivo que planteamos es analizar cómo Tomás López representó en su Atlas Geográfico de España (AGE de 1804, la arquitectura, el urbanismo y las obras públicas civiles y militares, un análisis hasta el momento inédito. Para ello se han caracterizado los diferentes símbolos cartográficos que aparecen en los mapas, que constituyen los parámetros de referencia del análisis y transmiten información fidedigna de la forma y significado de lo representado. Para esas tipologías se han encontrado ciento trece símbolos diferentes, lo que da idea de la minuciosidad y riqueza de la información contenida en los mapas. Dieciocho de ellos, son equivalentes con otros tantos símbolos cartográficos de Chevalier, maestro de D’Anville, de quien Tomás López fue discípulo en París. También hay una similitud entre cuatro símbolos del AGE con sus correspondientes signos de las Ordenanzas del Real Cuerpo de Ingenieros de 1803.

  2. Inseguridad ciudadana y diferenciación social en el nivel microbarrial: el caso del sector Santo Tomás, Santiago de Chile

    Directory of Open Access Journals (Sweden)

    Alejandra Lunecke

    2016-01-01

    Full Text Available En la periferia de la ciudad de Santiago se observan zonas de viviendas sociales que se caracterizan por una alta concentración de precariedades económicas y materiales, segregación espacial, procesos de debilitamiento del tejido comunitario y altos niveles de inseguridad, esto último por la presencia de grupos vinculados a la criminalidad. En tal contexto, a partir de una investigación realizada en el sector Santo Tomás de la zona sur de Santiago de Chile, se analiza cómo incide en los procesos de debilitamiento del tejido social, la percepción de inseguridad asociada al delito y la violencia, en un medio de pobreza guetizada. Para ello se pone énfasis en las prácticas discursivas de los vecinos, las que dan cuenta de los juicios de valor existentes respecto de "lo peligroso" y "lo desviado". Se discute cómo dichos juicios refuerzan las dinámicas de distinción social existentes en el nivel micro barrial y se alimentan de ellas.

  3. DANSIN İLK AKADEMİSYENİ: AGRİPPİNA VAGANOVA (YAŞAMI VE DANS EĞİTİM METODU)

    OpenAIRE

    KOÇKAR, M. Tekin

    2016-01-01

    Dünya Bale sanatının en teknik ve en güçlü eğitim sistemini yaratan Agrippina Vaganova’nın, öz yaşamı ve yaratmış olduğu teknik ile ilgili genel bilgiler bu çalışmanın konusunu oluşturmaktadır. Vaganova’nın dans eğitim metodu üç temel programa dayalıdır: Birincisi; Eğitimin her aşamasının en ayrıntılı biçimde planlanması, ikincisi; dansçının virtüözlük özelliklerini ortaya çıkaracak olan karmaşık egzersizlerin uygulanması, üçüncüsü ise; eğitim sürecinde ayrı ayrı her dansçının yapacağı hareke...

  4. A cidade africana contemporânea de origem portuguesa: São Tomé pré e pós-independência The contemporary African city of Portuguese origin: Sao Tome pre and post-independence

    Directory of Open Access Journals (Sweden)

    Teresa Madeira da Silva

    2012-12-01

    Full Text Available A cidade de São Tomé foi território português desde as primeiras ocupações até 1975 (data de sua independência,tendo, nesse tempo, crescido segundo os princípios do urbanismo de origem portuguesa. Para além da cidade planeada e consolidada, construída no período de ocupação colonial, a cidade desenvolveu, sobretudo no período pós-independência, um outro tipo de estrutura sem planeamento. À semelhança de outras cidades africanas de origem portuguesa, essa nova estrutura localiza-se na periferia do centro urbano. Este artigo apresenta dois argumentos. O primeiro considera que a cidade de São Tomé apresenta uma estrutura dual, tal como outras cidades africanas: uma zona central planeada, construída no período da ocupação colonial (pré-independência, e outra, periurbana, constituída essencialmente por habitações resultantes da expansão habitacional do centro urbano e com certas características semirrurais: vivendas associadas a espaços de produção agrícola familiar. O segundo argumento refere que tanto a estrutura central planeada, desenvolvida no período colonial, como a estrutura periférica não planeada, desenvolvida posteriormente,têm, na sua origem e desenvolvimento, a procura de relações com o território e, tanto numa como noutra,reconhecem-se estruturas urbanas adaptadas às condições locais.

  5. Genome-wide transcriptomic analysis of BR-deficient Micro-Tom reveals correlations between drought stress tolerance and brassinosteroid signaling in tomato.

    Science.gov (United States)

    Lee, Jinsu; Shim, Donghwan; Moon, Suyun; Kim, Hyemin; Bae, Wonsil; Kim, Kyunghwan; Kim, Yang-Hoon; Rhee, Sung-Keun; Hong, Chang Pyo; Hong, Suk-Young; Lee, Ye-Jin; Sung, Jwakyung; Ryu, Hojin

    2018-06-01

    Brassinosteroids (BRs) are plant steroid hormones that play crucial roles in a range of growth and developmental processes. Although BR signal transduction and biosynthetic pathways have been well characterized in model plants, their biological roles in an important crop, tomato (Solanum lycopersicum), remain unknown. Here, cultivated tomato (WT) and a BR synthesis mutant, Micro-Tom (MT), were compared using physiological and transcriptomic approaches. The cultivated tomato showed higher tolerance to drought and osmotic stresses than the MT tomato. However, BR-defective phenotypes of MT, including plant growth and stomatal closure defects, were completely recovered by application of exogenous BR or complementation with a SlDWARF gene. Using genome-wide transcriptome analysis, 619 significantly differentially expressed genes (DEGs) were identified between WT and MT plants. Several DEGs were linked to known signaling networks, including those related to biotic/abiotic stress responses, lignification, cell wall development, and hormone responses. Consistent with the higher susceptibility of MT to drought stress, several gene sets involved in responses to drought and osmotic stress were differentially regulated between the WT and MT tomato plants. Our data suggest that BR signaling pathways are involved in mediating the response to abiotic stress via fine-tuning of abiotic stress-related gene networks in tomato plants. Copyright © 2018. Published by Elsevier Masson SAS.

  6. Subclinical Enteric Parasitic Infections and Growth Faltering in Infants in São Tomé, Africa: A Birth Cohort Study

    Science.gov (United States)

    Garzón, Marisol; Seixas, Jorge; Papoila, Ana Luísa; Alves, Marta

    2018-01-01

    The associations between enteric pathogenic parasites and growth in infants in São Tomé were explored using a refined anthropometric approach to recognize early growth faltering. A birth cohort study was conducted with follow-up to 24 months of age. Microscopic examination for protozoa and soil-transmitted helminths was performed. Anthropometric assessments included: z-scores for weight-for-length (WLZ), length-for-age (LAZ), weight (WAVZ) and length velocities (LAVZ), length-for-age difference (LAD), and wasting and stunting risk (≤−1 SD). Generalized additive mixed effects regression models were used to explore the associations between anthropometric parameters and enteric parasitic infections and cofactors. A total of 475 infants were enrolled, and 282 completed the study. The great majority of infants were asymptomatic. Giardia lamblia was detected in 35.1% of infants in at least one stool sample, helminths in 30.4%, and Cryptosporidium spp. in 14.7%. Giardia lamblia and helminth infections were significantly associated with mean decreases of 0.10 in LAZ and 0.32 in LAD, and of 0.16 in LAZ and 0.48 in LAD, respectively. Cryptosporidium spp. infection was significantly associated with a mean decrease of 0.43 in WAVZ and 0.55 in LAVZ. The underestimated association between subclinical parasitic enteric infections and mild growth faltering in infants should be addressed in public health policies. PMID:29621166

  7. La Universidad Santo Tomás y su contribución en el campo de la educación a distancia en Colombia

    Directory of Open Access Journals (Sweden)

    Blanca Aurora Pita Torres

    2006-06-01

    Full Text Available La Universidad Santo Tomás ha contribuido en el cambio de la Educación Abierta y a Distancia en Colombia desde el año 1975 con diferentes programas tanto en Educación como en Ciencias y Tecnologías, cumpliendo así 31 años de experiencia en esta modalidad y consolidándose históricamente como la Institución Educativa con más prestigio e historia del país. La Vicerrectoría de Universidad Abierta y a Distancia, encargada de esta modalidad orienta toda su labor educativa en el conocimiento contextualizado, en la docencia, la ciencia y la tecnología, la investigación y lo valida en la proyección social que tiene como principios fundamentales: la persona humana que busca realizar un proyecto de vida, el saber para el servicio y el compromiso en la búsqueda del bie ncomún; al mismo tiempo que responde a las urgencia de hoy y a las demandas y posibilidades nacionales e internacionales.

  8. Tecnogénesis. La construcción técnica de las ecologías humanas (2 Volúmenes (Tomás Sánchez-Criado, Ed.

    Directory of Open Access Journals (Sweden)

    Pablo Santoro

    2009-05-01

    Full Text Available De ser necesaria una aproximación radicalmente reduccionista a un trabajo tan poliédrico, creo que podría resumirse parte del mensaje de Tecnogénesis. La construcción técnica de las ecologías humanas, la ambiciosa obra colectiva editada por Tomás Sánchez Criado, en dos de sus comienzos. El primero es el que abre el breve y hermoso preámbulo escrito por Florentino Blanco: una reflexión, al hilo de la asistencia del autor a un concierto de música vocal contemporánea, sobre la profunda modificación de la gramática musical clásica en la experimentación actual y sobre la confusión cognitiva y emocional a la que esta destrucción de los códigos acostumbrados arroja al espectador.

  9. Upper critical field of Mo-Ni heterostructures

    International Nuclear Information System (INIS)

    Uher, C.; Watson, W.J.; Cohn, J.L.; Schuller, I.K.

    1985-12-01

    Upper critical field and its anisotropy have been measured on two very short wavelength Mo-Ni heterostructures of different degrees of perfection, lambda = 13.8A (disordered structure) and lambda = 16.6A (layered structure). In both cases the parallel critical field has an unexpected temperature dependence, a large and temperature dependent anisotropy, and over 60% enhancement over the Clogston-Chandrasekhar limit. Data are fit to the Werthamer-Helfand-Hohenberg theory and the spin-orbit scattering times are found to be 1.79 x 10 -13 s and 2 x 10 -13 s, respectively

  10. Efficient azo dye decolorization in a continuous stirred tank reactor (CSTR) with built-in bioelectrochemical system.

    Science.gov (United States)

    Cui, Min-Hua; Cui, Dan; Gao, Lei; Cheng, Hao-Yi; Wang, Ai-Jie

    2016-10-01

    A continuous stirred tank reactor with built-in bioelectrochemical system (CSTR-BES) was developed for azo dye Alizarin Yellow R (AYR) containing wastewater treatment. The decolorization efficiency (DE) of the CSTR-BES was 97.04±0.06% for 7h with sludge concentration of 3000mg/L and initial AYR concentration of 100mg/L, which was superior to that of the sole CSTR mode (open circuit: 54.87±4.34%) and the sole BES mode (without sludge addition: 91.37±0.44%). The effects of sludge concentration and sodium acetate (NaAc) concentration on azo dye decolorization were investigated. The highest DE of CSTR-BES for 4h was 87.66±2.93% with sludge concentration of 12,000mg/L, NaAc concentration of 2000mg/L and initial AYR concentration of 100mg/L. The results in this study indicated that CSTR-BES could be a practical strategy for upgrading conventional anaerobic facilities against refractory wastewater treatment. Copyright © 2016 Elsevier Ltd. All rights reserved.

  11. FINDIK KABUKLARININ, ÇAY VE TÜTÜN ATIKLARININ HAMMADDE OLARAK KULLANILMASI

    Directory of Open Access Journals (Sweden)

    Ş. İsmail KIRBAŞLAR

    2001-01-01

    Full Text Available Bu çalışmada, fındık kabukları, çay ve tütün atıklarındaki nem, kül, yağ ve sellüloz miktarları analiz edilmiştir. Ayrıca, fındık kabukları, çay ve tütün atıklarının içerdiği pentosan, pentos ve furfural miktarları belirlenmiştir. Furfural her üç atıktan destilasyon metoduyla ayrılmıştır. Atıklardan ayrılan furfural örneklerinin IRspektrumları ile standart furfuralin IR-spektrumları karşılaştırılmıştır. Fındık kabuklarından farklı sıcaklıklarda aktif karbon elde edilmiştir. Bu aktif karbon kullanılarak organik ve anarganik atıklar adsorbsiyonla uzaklaştırılmıştır.

  12. İLETİŞİM İKLİMİNİN, İŞ DOYUMU VE İŞDEN AYRILMA NİYETİ İLİŞKİSİNE ETKİSİ - THE MODERATING EFFECT OF COMMUNICATION CLIMATE BETWEEN JOB SATISFACTION AND TURNOVER INTENTION

    Directory of Open Access Journals (Sweden)

    Ela ÜNLER

    2014-01-01

    Full Text Available ÖzetÇalışmanın amacı, iş doyumu ve iletişim ikliminin çalışanların işden ayrılma niyetlerine etkisini incelemektir. Ayrıca, iletişim ikliminin iş doyumu ve işden ayrılma niyeti ilişkisinde şartlı değişken olarak rol alıp almadığı anlaşılmaya çalışılmıştır. Çalışmaya Türkiye’de bankacılık sektöründe çalışan 182 kişi katılmıştır. Katılımcıların 96’sı kadın 84’ü erkekir. Araştırmanın sonuçlarına göre, iş doyumu ve iletişim ikliminin işden ayrılma niyeti ile olumsuz ilişki içinde olduğu görülmüştür. İş doyumu yüksek ve olumlu iletişim iklime sahip şirketlerde çalışanların işden ayrılma niyetlerinin azaldığı anlaşılmıştır. Ayrıca, iletişim iklimi boyutlarından, yönetici-çalışan iletişimi ve iletişimde şeffaflık ve güvenin, dışsal kaynaklı iş doyumu ve işden ayrılma niyeti ilişkisinde şartlı değişken olarak görev yaptığı bulunmuştur. Çalışmanın tartışma bölümünde kısıtları ve katkıları aktarılmıştır.AbstractThe aim of the study was to explore the effect of job satisfaction on turnover intentions of employees. It was also investigated if communication climate has a moderating effect on the satisfaction-turnover intentions relationship. 182 questionnaires were collected from individuals who were working in the banking industry. The sample was comprised of 97 women and 85 men. Results indicated that, job satisfaction and communication climate both have a negativeeffect on turnover intentions of employees. Participants working in companies with a positivecommunication climate and high levels of job satisfaction displayed a lower levels of turnoverintentions. Furthermore, two of the communication climate dimensions: supervisor-subordinatecommunication, openness and trust in communication were found to have a moderating rolebetween external job satisfaction and turnover intention. Managerial implications and

  13. İLETİŞİM İKLİMİNİN, İŞ DOYUMU VE İŞDEN AYRILMA NİYETİ İLİŞKİSİNE ETKİSİ - THE MODERATING EFFECT OF COMMUNICATION CLIMATE BETWEEN JOB SATISFACTION AND TURNOVER INTENTION

    Directory of Open Access Journals (Sweden)

    Ela ÜNLER

    2014-03-01

    Full Text Available ÖzetÇalışmanın amacı, iş doyumu ve iletişim ikliminin çalışanların işden ayrılma niyetlerine etkisini incelemektir. Ayrıca, iletişim ikliminin iş doyumu ve işden ayrılma niyeti ilişkisinde şartlı değişken olarak rol alıp almadığı anlaşılmaya çalışılmıştır. Çalışmaya Türkiye’de bankacılık sektöründe çalışan 182 kişi katılmıştır. Katılımcıların 96’sı kadın 84’ü erkekir. Araştırmanın sonuçlarına göre, iş doyumu ve iletişim ikliminin işden ayrılma niyeti ile olumsuz ilişki içinde olduğu görülmüştür. İş doyumu yüksek ve olumlu iletişim iklime sahip şirketlerde çalışanların işden ayrılma niyetlerinin azaldığı anlaşılmıştır. Ayrıca, iletişim iklimi boyutlarından, yönetici-çalışan iletişimi ve iletişimde şeffaflık ve güvenin, dışsal kaynaklı iş doyumu ve işden ayrılma niyeti ilişkisinde şartlı değişken olarak görev yaptığı bulunmuştur. Çalışmanın tartışma bölümünde kısıtları ve katkıları aktarılmıştır.AbstractThe aim of the study was to explore the effect of job satisfaction on turnover intentions of employees. It was also investigated if communication climate has a moderating effect on the satisfaction-turnover intentions relationship. 182 questionnaires were collected from individuals who were working in the banking industry. The sample was comprised of 97 women and 85 men. Results indicated that, job satisfaction and communication climate both have a negativeeffect on turnover intentions of employees. Participants working in companies with a positivecommunication climate and high levels of job satisfaction displayed a lower levels of turnoverintentions. Furthermore, two of the communication climate dimensions: supervisor-subordinatecommunication, openness and trust in communication were found to have a moderating rolebetween external job satisfaction and turnover intention. Managerial implications and

  14. ʻWhere danger is, there rescue growsʼ: Technology, Time, and Dromology in Tom McCarthy’s C

    Directory of Open Access Journals (Sweden)

    Joakim Wrethed

    2017-12-01

    Full Text Available On one level, Tom McCarthy’s 'C' comes out as a postmodern intertextual patchwork that borrows the form of the 'Bildungsroman'. Accordingly, the protagonist Serge travels from birth to death in a forthrightly chronological narrative, but that journey is accompanied by the fact that the text’s modernist historical context is partly embedded in a posthuman and postmodern ontology. Technologically speaking, this version of modernity displays itself as 'technē', both in terms of artistic creation and as technology innovation (the radio transmitter, the car, the aeroplane, the cinema. Moreover, the novel equates technology with dromology (from Gr. 'dromos': race course dealing with increasing speed as economic and political advantage, but it also reveals its human downside in terms of disaster (war, car crash, aeroplane crash. Through the protagonist, C forwards technology as death drive and the human as always already being 'ahuman' ('technē' as primordial attribute of 'bios'. In terms of time, the narrative seemingly incarnates the occidental obsession with teleology and eschatology. This article goes through these dimensions, but in addition it contends that there is another level at work in the narrative. Considered as artistically rendered philosophical cognition, the novel puts forth the Stoic 'apathea' (equanimity, Husserlian flux, and anachronistic temporality as giving way to a peculiar kind of faith. This is closely tied to the artistic creativity of 'technē', including the activity of writing, which rescues a form of transcendence from conventional postmodern elimination. Dominant discourses of technology and time—apocalyptic and utopian—are challenged in this reading.

  15. Unique Theory of Mind Differentiation in Children with Autism and Asperger Syndrome

    OpenAIRE

    Tine, Michele; Lucariello, Joan

    2012-01-01

    This study was designed to determine if ToM abilities of children with autism and Asperger syndrome differentiate into Intrapersonal ToM and Social ToM. A battery of Social and Intrapersonal ToM tasks was administered to 39 children with autism and 34 children with Asperger syndrome. For both groups of children, ToM differentiated and Intrapersonal ToM was stronger than Social ToM. This asymmetry was greater for children with autism, whose Social ToM was especially weak. These results support...

  16. Kadın Kütüphaneciler: Toplumsal Cinsiyet Sorunları = Female Librarians: Gender Issues

    Directory of Open Access Journals (Sweden)

    Murat Yılmaz

    2013-06-01

    Full Text Available Bu araştırmanın amacı, kadın kütüphanecilerin cinsiyet ayrımcılığından dolayı kütüphanelerde karşılaşacakları olası sorunları irdelemektir. Bu amaç doğrultusunda araştırmada, kadın kütüphanecilerin kütüphanelerde karşılaşacakları sorunlar şu şekilde ayrılmıştır; ○ kütüphanelerde cinsel istismar (mobbing; ○ ücret ayrımcılığı (kadın kütüphaneci olarak düşük ücret alma ○ kariyer gelişiminde cinsiyet ayrımcılığı; ○ kadın kütüphaneci olarak haksız yere işten çıkarılma ○ kadın kütüphaneci olarak kariyere ara verme (evlilik ya da bebek sahibi olma gibi nedenler ve ○ iş görüşmelerinde kişisel sorularla karşılaşma (evlilikle ya da annelikle ilgili zamanlamayla ilgili sorular. Ayrıca araştırmada, kadın kütüphanecilerin cinsiyet ayrımcılığına ilişkin kütüphanelerde karşılaşacakları yukarıda sıralanan sorunlara ilişkin çeşitli çözüm önerileri de tartışılmıştır./The purpose of this study is to examine the possible problems being met by female librarians due to gender discrimination in libraries. With this purpose in this study, the relevant problems being met by female librarians in libraries are divided as follows; sexual harassment (mobbing in libraries, wage discrimination (receiving a low wage as a female librarian, gender discrimination in career development, unfair dismissal as a female librarian, career break as a female librarian (because of marriage or having a new baby, and encountering the personal questions in job interviews (such as the questions of the timing of marriage or motherhood. Furthermore, in the study, various recommendations for solving the above problems of gender discrimination met by female librarians in libraries have been also discussed.

  17. Unique Theory of Mind Differentiation in Children with Autism and Asperger Syndrome

    Directory of Open Access Journals (Sweden)

    Michele Tine

    2012-01-01

    Full Text Available This study was designed to determine if ToM abilities of children with autism and Asperger syndrome differentiate into Intrapersonal ToM and Social ToM. A battery of Social and Intrapersonal ToM tasks was administered to 39 children with autism and 34 children with Asperger syndrome. For both groups of children, ToM differentiated and Intrapersonal ToM was stronger than Social ToM. This asymmetry was greater for children with autism, whose Social ToM was especially weak. These results support a differentiated, as opposed to integrated, ToM. Moreover, the findings provide a more thorough understanding of the cognitive abilities associated with autism and Asperger syndrome.

  18. Population Genetics of the São Tomé Caecilian (Gymnophiona: Dermophiidae: Schistometopum thomense) Reveals Strong Geographic Structuring

    Science.gov (United States)

    Stoelting, Ricka E.; Measey, G. John; Drewes, Robert C.

    2014-01-01

    Islands provide exciting opportunities for exploring ecological and evolutionary mechanisms. The oceanic island of São Tomé in the Gulf of Guinea exhibits high diversity of fauna including the endemic caecilian amphibian, Schistometopum thomense. Variation in pigmentation, morphology and size of this taxon over its c. 45 km island range is extreme, motivating a number of taxonomic, ecological, and evolutionary hypotheses to explain the observed diversity. We conducted a population genetic study of S. thomense using partial sequences of two mitochondrial DNA genes (ND4 and 16S), together with morphological examination, to address competing hypotheses of taxonomic or clinal variation. Using Bayesian phylogenetic analysis and Spatial Analysis of Molecular Variance, we found evidence of four geographic clades, whose range and approximated age (c. 253 Kya – 27 Kya) are consistent with the spread and age of recent volcanic flows. These clades explained 90% of variation in ND4 (φCT = 0.892), and diverged by 4.3% minimum pairwise distance at the deepest node. Most notably, using Mismatch Distributions and Mantel Tests, we identified a zone of population admixture that dissected the island. In the northern clade, we found evidence of recent population expansion (Fu's Fs = −13.08 and Tajima's D = −1.80) and limited dispersal (Mantel correlation coefficient = 0.36, p = 0.01). Color assignment to clades was not absolute. Paired with multinomial regression of chromatic data, our analyses suggested that the genetic groups and a latitudinal gradient together describe variation in color of S. thomense. We propose that volcanism and limited dispersal ability are the likely proximal causes of the observed genetic structure. This is the first population genetic study of any caecilian and demonstrates that these animals have deep genetic divisions over very small areas in accordance with previous speculations of low dispersal abilities. PMID:25171066

  19. VizieR Online Data Catalog: The FIRST Survey Catalog, Version 2014Dec17 (Helfand+ 2015)

    Science.gov (United States)

    Helfand, D. J.; White, R. L.; Becker, R. H.

    2015-05-01

    The Faint Images of the Radio Sky at Twenty centimeters (FIRST) began in 1993. It uses the VLA (Very Large Array, a facility of the National Radio Observatory (NRAO)) at a frequency of 1.4GHz, and it is slated to 10,000 deg2 of the North and South Galactic Caps, to a sensitivity of about 1mJy with an angular resolution of about 5''. The images produced by an automated mapping pipeline have pixels of 1.8'', a typical rms of 0.15mJy, and a resolution of 5''; the images are available on the Internet (see the FIRST home page at http://sundog.stsci.edu/ for details). The source catalogue is derived from the images. This catalog from the 1993 through 2011 observations contains 946,432 sources from the north and south Galactic caps. It covers a total of 10,575 square degrees of the sky (8444 square degrees in the north and 2131 square degrees in the south). In this version of the catalog, images taken in the the new EVLA configuration have been re-reduced using shallower CLEAN thresholds in order to reduce the "CLEAN bias" in those images. Also, the EVLA images are not co-added with older VLA images to avoid problems resulting from the different frequencies and noise properties of the configurations. That leads to small gaps in the sky coverage at boundaries between the EVLA and VLA regions. As a result, the area covered by this release of the catalog is about 60 square degrees smaller than the earlier release of the catalog (13Jun05, also available here as the "first13.dat" file), and the total number of sources is reduced by nearly 25,000. The previous version of the catalog does have sources in the overlap regions, but their flux densities are considered unreliable due to calibration errors. The flux densities should be more accurate in this catalog, biases are smaller, and the incidence of spurious sources is also reduced. Over most of the survey area, the detection limit is 1 mJy. A region along the equatorial strip (RA=21.3 to 3.3hr, Dec=-1 to 1deg) has a deeper detection threshold because two epochs of observation were combined. The typical detection threshold in this region is 0.75mJy. There are approximately 4,500 sources below the 1mJy threshold used for most previous versions of the catalog. The previous versions http://sundog.stsci.edu/first/catalogs/ (2 data files).

  20. Neural processing associated with cognitive and affective Theory of Mind in adolescents and adults.

    Science.gov (United States)

    Sebastian, Catherine L; Fontaine, Nathalie M G; Bird, Geoffrey; Blakemore, Sarah-Jayne; Brito, Stephane A De; McCrory, Eamon J P; Viding, Essi

    2012-01-01

    Theory of Mind (ToM) is the ability to attribute thoughts, intentions and beliefs to others. This involves component processes, including cognitive perspective taking (cognitive ToM) and understanding emotions (affective ToM). This study assessed the distinction and overlap of neural processes involved in these respective components, and also investigated their development between adolescence and adulthood. While data suggest that ToM develops between adolescence and adulthood, these populations have not been compared on cognitive and affective ToM domains. Using fMRI with 15 adolescent (aged 11-16 years) and 15 adult (aged 24-40 years) males, we assessed neural responses during cartoon vignettes requiring cognitive ToM, affective ToM or physical causality comprehension (control). An additional aim was to explore relationships between fMRI data and self-reported empathy. Both cognitive and affective ToM conditions were associated with neural responses in the classic ToM network across both groups, although only affective ToM recruited medial/ventromedial PFC (mPFC/vmPFC). Adolescents additionally activated vmPFC more than did adults during affective ToM. The specificity of the mPFC/vmPFC response during affective ToM supports evidence from lesion studies suggesting that vmPFC may integrate affective information during ToM. Furthermore, the differential neural response in vmPFC between adult and adolescent groups indicates developmental changes in affective ToM processing.

  1. A Longitudinal Study of Predictors of Sexual Dysfunction in Men on Active Surveillance for Prostate Cancer

    Directory of Open Access Journals (Sweden)

    Shane M. Pearce, MD

    2015-09-01

    Conclusions: Men on AS experienced a gradual decline in sexual function during the first 24 months of enrollment. Older age, PSA × time, and diabetes were all independent predictors of diminished sexual function over time. Anxiety, AUA‐SI, the number of cores and the number of biopsies were not predictors of reduced sexual function in men in AS. Pearce SM, Wang CHE, Victorson DE, Helfand BT, Novakovic KR, Brendler CB, and Albaugh JA. A longitudinal study of predictors of sexual dysfunction in men on active surveillance for prostate cancer. Sex Med 2015;3:156–164.

  2. Viscosity calculations at molecular dynamics simulations

    International Nuclear Information System (INIS)

    Kirova, E M; Norman, G E

    2015-01-01

    Viscosity and diffusion are chosen as an example to demonstrate the universality of diagnostics methods in the molecular dynamics method. To emphasize the universality, three diverse systems are investigated, which differ from each other drastically: liquids with embedded atom method and pairwise interatomic interaction potentials and dusty plasma with a unique multiparametric interparticle interaction potential. Both the Einstein-Helfand and Green-Kubo relations are used. Such a particular process as glass transition is analysed at the simulation of the aluminium melt. The effect of the dust particle charge fluctuation is considered. The results are compared with the experimental data. (paper)

  3. The influence of secondary reconstruction slice thickness on NewTom 3G cone beam computed tomography-based radiological interpretation of sheep mandibular condyle fractures.

    Science.gov (United States)

    Sirin, Yigit; Guven, Koray; Horasan, Sinan; Sencan, Sabri; Bakir, Baris; Barut, Oya; Tanyel, Cem; Aral, Ali; Firat, Deniz

    2010-11-01

    The objective of this study was to examine the diagnostic accuracy of the different secondary reconstruction slice thicknesses of cone beam computed tomography (CBCT) on artificially created mandibular condyle fractures. A total of 63 sheep heads with or without condylar fractures were scanned with a NewTom 3G CBCT scanner. Multiplanar reformatted (MPR) views in 0.2-mm, 1-mm, 2-mm, and 3-mm secondary reconstruction slice thicknesses were evaluated by 7 observers. Inter- and intraobserver agreements were calculated with weighted kappa statistics. The receiver operating characteristic (ROC) curve analysis was used to statistically compare the area under the curve (AUC) of each slice thickness. The kappa coefficients varied from fair and to excellent. The AUCs of 0.2-mm and 1-mm slice thicknesses were found to be significantly higher than those of 2 mm and 3 mm for some type of fractures. CBCT was found to be accurate in detecting all variants of fractures at 0.2 mm and 1 mm. However, 2-mm and 3-mm slices were not suitable to detect fissure, complete, and comminuted types of mandibular condyle fractures. Copyright © 2010 Mosby, Inc. All rights reserved.

  4. Assessment of nasal spray deposition pattern in a silicone human nose model using a color-based method.

    Science.gov (United States)

    Kundoor, Vipra; Dalby, Richard N

    2010-01-01

    To develop a simple and inexpensive method to visualize and quantify droplet deposition patterns. Deposition pattern was determined by uniformly coating the nose model with Sar-Gel (a paste that changes from white to purple on contact with water) and subsequently discharging sprays into the nose model. The color change was captured using a digital camera and analyzed using Adobe Photoshop. Several tests were conducted to validate the method. Deposition patterns of different nasal sprays (Ayr, Afrin, and Zicam) and different nasal drug delivery devices (Afrin nasal spray and PARI Sinustar nasal nebulizer) were compared. We also used the method to evaluate the effect of inhaled flow rate on nasal spray deposition. There was a significant difference in the deposition area for Ayr, Afrin, and Zicam. The deposition areas of Afrin nasal spray and PARI Sinustar nasal nebulizer (2 min and 5 min) were significantly different. Inhaled flow rate did not have a significant effect on the deposition pattern. Lower viscosity formulations (Ayr, Afrin) provided greater coverage than the higher viscosity formulation (Zicam). The nebulizer covered a greater surface area than the spray pump we evaluated. Aerosol deposition in the nose model was not affected by air flow conditions.

  5. Combining ability of tomato lines in saladette-type hybrids

    Directory of Open Access Journals (Sweden)

    Marcela Carvalho Andrade

    2014-09-01

    Full Text Available Given the growing importance of the saladette fresh tomato market in Brazil, the objective of this paper was to assess the combining abilities of lines potentially useful as parents of hybridsin this class. The experiment consisted of28 genotypes, 18 hybrids from a partial diallel crossobtained from crossing two groups of tomato lines (Group I, with 9 parents, and Group II, with 2 parents, 8 F1 experimental hybrids, and 2 commercial checks. Traits evaluated were total yield, mean fruit mass, fruit shelf life, shape and percentsoluble solids. Additive genetic effects were generally more important than non-additive effects for all traits evaluated. The TOM-542 and TOM-734 lines, from group I, and the TOM-720 line, from group II, presented high general combining ability (GCA estimates for most of the traits of importance for saladette tomatoes, and were therefore considered suitable parents of hybrids of this class. Higher fruit shelf life of TOM-723 as a parental line compared with TOM-720 (Group II, was mainly attributed to the presence in the former of the norA allele, which controls longer fruit shelf life. F1 hybrids (TOM-542 x TOM-720, (TOM-580 x TOM-720, (TOM-734 x TOM-720, and (TOM-727 x TOM-720 showed good performance and fruit quality and thus constitute possible commercial varieties.

  6. Análisis Del Impacto Del Acompañamiento Psicológico En El Rendimiento Académico De Los Estudiantes De La División De Ingenierías De La Universidad Santo Tomás -Bogotá

    OpenAIRE

    Galán, Lina; Guillén, Sandra; Mogollón, Edna

    2016-01-01

    El acompañamiento y seguimiento a los estudiantes universitarios se ha convertido en una práctica necesaria, con el fin de conocer cuáles son las situaciones por las cuales atraviesan los jóvenes y que pueden llegar a afectar de manera directa su rendimiento. Son insuficientes las tutorías académicas, las cuales no alcanzan a generar una comprensión holística del ser integral que abarca sus demás dimensiones. La Universidad Santo Tomás, tiene como desarrollo misional la formación integral de ...

  7. Tom, Tom, the Piper's Son: Reading While Having Fun.

    Science.gov (United States)

    Holmes, Kerry

    2003-01-01

    This article describes how a first-grade teacher used poetry to provide students of diverse ability levels with reading and language activities that stimulated their interest and improved basic skills. Activities with poetry included reading the poems aloud individually and as a group, discussing and analyzing the poems' words and meanings, and…

  8. CIFRAS CON SENTIDO: Articulación Del Proceso De Acompañamiento Estudiantil Con El Sistema De Gestión De La Calidad Del Departamento De Humanidades Y Formación Integral De La Universidad Santo Tomás Bogotá

    OpenAIRE

    Cely Atuesta, Diana Catherine; Riaño, Adriana; Latorre, Kenia

    2016-01-01

    El Departamento de Humanidades y Formación Integral (DHFI), de la Universidad Santo Tomás (USTA) Bogotá - Colombia, es una instancia académica que tiene como misión “promover los procesos de Formación Integral de la Comunidad Universitaria y aportar elementos para desarrollar actitud y conciencia críticas, a la luz del pensamiento tomista de la educación” (Documento Marco DHFI, 2014). Las cátedras del DHFI hacen parte de los planes de formación de todos los programas de la USTA a partir de 7 ...

  9. Sistema de Información para el proceso de acreditación de la Universidad Santo Tomás de Tunja

    Directory of Open Access Journals (Sweden)

    Ivan Fernando Fonseca Barinas

    2011-05-01

    Full Text Available El Sistema de Información para el Proceso de Acreditación de la Universidad Santo Tomás es el esfuerzo de muchas personas que colaboraron en el proyecto de forma permanente, no solo para plantear una solución a la administración de la información generada en el proceso de acreditación, sino también para involucrarse realmente en el mejoramiento continuo de cada facultad y con el compromiso de alcanzar la misión de la institución. El presente trabajo detalla cómo en la etapa de diseño se modeló la realidad del proceso de acreditación con la ayuda de diferentes diagramas: diagrama arquitectónico, diagrama entidad relación y el diagrama de clases que encapsula la lógica del negocio. Al concluir el diseño se inició la tarea de implementar el sistema, para esto se utilizó el patrón Modelo Vista Controlador. En el modelo se creó la base de datos con sus tablas y atributos, así como también se crearon las clases utilizando la arquitectura JEE. Para la vista se manejó el framework de ICEfaces buscando una interfaz amigable con componentes ricos que ayudan al usuario a trabajar fácilmente en la aplicación.

  10. Association of enteric parasitic infections with intestinal inflammation and permeability in asymptomatic infants of São Tomé Island.

    Science.gov (United States)

    Garzón, Marisol; Pereira-da-Silva, Luis; Seixas, Jorge; Papoila, Ana Luísa; Alves, Marta; Ferreira, Filipa; Reis, Ana

    2017-05-01

    The cumulative effect of repeated asymptomatic enteric infections on intestinal barrier is not fully understood in infants. We aimed to evaluate the association between previous enteric parasitic infections and intestinal inflammation and permeability at 24-months of age, in asymptomatic infants of São Tomé Island. A subset of infants from a birth cohort, with intestinal parasite evaluations in at least four points of assessment, was eligible. Intestinal inflammatory response and permeability were assessed using fecal S100A12 and alpha-1-antitrypsin (A1AT), respectively. The cutoff parasitic infections explained variability of fecal biomarkers, after adjusting for potential confounders. Eighty infants were included. Giardia duodenalis and soil-transmitted helminths (STH) were the most frequent parasites. The median (interquartile range) levels were 2.87 μg/g (2.41-3.92) for S100A12 and 165.1 μg/g (66.0-275.6) for A1AT. Weak evidence of association was found between S100A12 levels and G. duodenalis (p = 0.080) and STH infections (p = 0.089), and between A1AT levels and parasitic infection of any etiology (p = 0.089), at 24-months of age. Significant associations between A1AT levels and wasting (p = 0.006) and stunting (p = 0.044) were found. Previous parasitic infections were not associated with fecal biomarkers at 24 months of age. To summarize, previous asymptomatic parasitic infections showed no association with intestinal barrier dysfunction. Notwithstanding, a tendency toward increased levels of the inflammatory biomarker was observed for current G. duodenalis and STH infections, and increased levels of the permeability biomarker were significantly associated with stunting and wasting.

  11. Evaluating Ultraviolet Radiation Exposures Determined from TOMS Satellite Data at Sites of Amphibian Declines in Central and South America

    Science.gov (United States)

    Middleton, Elizabeth M.; Smith, David E. (Technical Monitor)

    2000-01-01

    Many amphibian species have experienced substantial population declines, or have disappeared altogether, during the last several decades at a number of amphibian census sites in Central and South America. This study addresses the use of satellite-derived trends in solar ultraviolet-B (UV-B; 280-320 nm) radiation exposures at these sites over the last two decades, and is intended to demonstrate a role for satellite observations in determining whether UV-B radiation is a contributing factor in amphibian declines. UV-B radiation levels at the Earth's surface were derived from the Total Ozone Mapping Spectrometer (TOMS) satellite data, typically acquired daily since 1979. These data were used to calculate the daily erythemal (sunburning) UV-B, or UV-B(sub ery), exposures at the latitude, longitude, and elevation of each of 20 census sites. The annually averaged UV-B(sub ery) dose, as well as the maximum values, have been increasing in both Central and South America, with higher levels received at the Central American sites. The annually averaged UV-B(sub ery) exposures increased significantly from 1979-1998 at all 11 Central American sites examined (r(exp 2) = 0.60 - 0.79; P= 6750 J/sq m*d) to the annual UV-B(sub ery) total has increased from approx. 5% to approx. 15% in Central America over the 19 year period, but actual daily exposures for each species are unknown. Synergy among UV-B radiation and other factors, especially those associated with alterations of water chemistry (e.g., acidification) in aqueous habitats is discussed. These findings justify further research concerning whether UV-B(sub ery) radiation plays a role in amphibian population declines and extinctions.

  12. Phenolic characterization and variability in leaves, stems and roots of Micro-Tom and patio tomatoes, in response to nitrogen limitation.

    Science.gov (United States)

    Larbat, Romain; Paris, Cédric; Le Bot, Jacques; Adamowicz, Stéphane

    2014-07-01

    Phenolics are implicated in the defence strategies of many plant species rendering their concentration increase of putative practical interest in the field of crop protection. Little attention has been given to the nature, concentration and distribution of phenolics within vegetative organs of tomato (Solanum lycopersicum. L) as compared to fruits. In this study, we extensively characterized the phenolics in leaves, stems and roots of nine tomato cultivars using high-performance liquid chromatography coupled to electrospray ionization tandem mass spectrometry (LC-MS(n)) and assessed the impact of low nitrogen (LN) availability on their accumulation. Thirty-one phenolics from the four sub-classes, hydroxycinnamoyl esters, flavonoids, anthocyanins and phenolamides were identified, five of which had not previously been reported in these tomato organs. A higher diversity and concentration of phenolics was found in leaves than in stems and roots. The qualitative distribution of these compounds between plant organs was similar for the nine cultivars with the exception of Micro-Tom because of its significantly higher phenolic concentrations in leaves and stems as compared to roots. With few exceptions, the influence of the LN treatment on the three organs of all cultivars was to increase the concentrations of hydroxycinnamoyl esters, flavonoids and anthocyanins and to decrease those of phenolamides. This impact of LN was greater in roots than in leaves and stems. Nitrogen nutrition thus appears as a means of modulating the concentration and composition of organ phenolics and their distribution within the whole plant. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  13. Social cognition: empirical contribution. The developmental building blocks of psychopathic traits: revisiting the role of theory of mind.

    Science.gov (United States)

    Sharp, Carla; Vanwoerden, Salome

    2014-02-01

    In the context of personality disorder development, theories of typical and atypical development both emphasize social cognition as an important building block for personality development. Prior claims of intact theory of mind (ToM) abilities in psychopathic individuals have relied upon a narrow conception of ToM as equivalent to "cognitive empathy." In this article, the authors make use of a broader conception of ToM comprising top-down and bottom-up processing, as well as the fractionation of ToM in terms of reduced or excessive ToM function, to examine relationships between ToM and psychopathic traits. A total of 342 adolescents (ages 12-17; Mage 15.39; SD = 1.45; 61.5% females) completed the Movie Assessment for Social Cognition (Dziobek, Fleck, Kalbe, et al., 2006) and the Child Eyes Test (Baron-Cohen, Wheelwright, Hill, Raste, & Plumb, 2001) in addition to three measures of psychopathic traits. Results demonstrated unique relations between the affective components of psychopathy (callous-unemotional traits [CU traits]) and impairment in both top-down and bottom-up ToM. In addition, excessive ToM related to affective components of psychopathy, while reduced or no ToM related to behavioral components of psychopathy. In mediational analyses, bottom-up ToM was shown to be necessary for top-town ToM in its relation with CU traits. Taken together, these results from the study lend support to revisiting the link between ToM and psychopathy.

  14. The relation between theory of mind and executive functions in children with fetal alcohol spectrum disorders.

    Science.gov (United States)

    Rasmussen, Carmen; Wyper, Katy; Talwar, Victoria

    2009-01-01

    Children with Fetal Alcohol Spectrum Disorders (FASD) are faced with a range of physical, cognitive, behavioral, and/or learning deficits, as well as poor executive functioning and social skills. Theory of mind (ToM) is the ability to understand that one's own perspective may differ from the perspective of another individual. ToM develops around age 4 and is correlated with performance on executive functioning tasks. The goals of this study were to examine ToM performance in young children with FASD, how age was related to ToM performance, and whether ToM abilities were related to underlying executive function difficulties. Fifty-three children (aged 4 to 8 years) participated: 25 children with FASD and 28 control children. All children were tested on measures of ToM, executive functioning, and receptive vocabulary. More children in the FASD group (44%) failed one or both ToM measures than in the control group (25%). Older children with FASD performed worse on ToM than younger children, but this was not the case for the control group. For the FASD group, ToM performance was correlated with a measure of inhibition, but for the control group, ToM was correlated with visual-spatial working memory. Children with FASD have difficulty on ToM tasks, and this difficulty may be related to underlying deficits in inhibition.

  15. Protein Esaslı Yağ İkame Maddesi Kullanımının Yağsız Yoğurdun Kalitesi Üzerine Etkisi

    Directory of Open Access Journals (Sweden)

    Fatma Sezen

    2015-02-01

    Full Text Available Bu çalışmada, protein esaslı yağ ikame maddesi olan Dairy-Lo™ 'nun %1 ve %2 gibi iki farklı oranı kullanılarak, rekonstitüe sütten üretilen, yağsız set tipi yoğurtların fiziksel, kimyasal, tekstürel ve duyusal özellikleri incelenmiştir. Yoğurt örneklerinde depolamanın 1., 7. ve 15. günlerinde titrasyon asitliği, pH, asetaldehit, laktik asit, serum ayrılması, viskozite, konsistens değerleri saptanmıştır. Ayrıca yoğurt örneklerinde duyusal değerlendirmeler de yapılmıştır.  Bu çalışma sonucu elde edilen bulgular, protein esaslı yağ ikame maddesi Dairy-Lo™ ilavesinin yağsız yoğurdun konsistens ve viskozitesini artırıp, serum ayrılmasını azalttığını göstermiştir. Dairy-Lo™ 'nun %2 oranında kullanımının yağsız set tip yoğurdun kalitesini iyileştirdiği belirlenmiştir.

  16. The relationship between theory of mind and the executive functions: Evidence from patients with frontal lobe damage.

    Science.gov (United States)

    Yeh, Zai-Ting; Tsai, Ming-Cheng; Tsai, Ming-Dar; Lo, Chiao-Yu; Wang, Kaw-Chen

    2017-01-01

    "Theory of mind" (ToM) refers to the ability to predict others' thoughts, intentions, beliefs, and feelings. Evidence from neuropsychology and functional imaging indicates that ToM is a domain-specific or modular architecture; however, research in development psychology has suggested that ToM is the full development of the executive functions in individuals. Therefore, the relationship between ToM and the executive functions needs to be clarified. Since the frontal lobe plays a critical role in the abilities of ToM and the executive functions, patients with frontal lobe damage were recruited for the present study. Assessments of ToM and the executive functions were performed on 23 patients with frontal lobe damage and 20 healthy controls. When controlling for the executive functions, significant differences between the patient and normal groups were found in the affective component of ToM, but not in the cognitive component. The present study suggests that in various social situations, executing ToM abilities requires logical reasoning processes provided by the executive functions. However, the reasoning processes of affective ToM are independent of executive functions.

  17. Using virtual reality to assess theory of mind subprocesses and error types in early and chronic schizophrenia.

    Science.gov (United States)

    Canty, Allana L; Neumann, David L; Shum, David H K

    2017-12-01

    Individuals with schizophrenia often demonstrate theory of mind (ToM) impairment relative to healthy adults. However, the exact nature of this impairment (first- vs. second-order ToM and cognitive vs. affective ToM) and the extent to which ToM abilities deteriorate with illness chronicity is unclear. Furthermore, little is known about the relationships between clinical symptoms and ToM error types (overmentalising, reduced mentalising and no ToM) in early and chronic schizophrenia. This study examined the nature and types of ToM impairment in individuals with early ( n  = 26) and chronic schizophrenia ( n  = 32) using a novel virtual reality task. Clinical participants and demographically-matched controls were administered the Virtual Assessment of Mentalising Ability, which provides indices of first- and second-order cognitive and affective ToM, and quantifies three different types of mentalising errors (viz., overmentalising, reduced mentalising, and no ToM). Individuals with early schizophrenia performed significantly poorer than healthy controls on first-order affective and second-order cognitive and affective ToM, but significantly higher than individuals with chronic schizophrenia on all ToM subscales. Whereas a lack of mental state concept was associated with negative symptoms, overmentalising was associated with positive symptoms. These findings suggest that ToM abilities selectively deteriorate with illness chronicity and error types are related to these individuals' presenting symptomology. An implication of the findings is that social-cognitive interventions for schizophrenia need to consider the nature, time course and symptomatology of the presenting patient.

  18. Promoting theory of mind in older adults: does age play a role?

    Science.gov (United States)

    Rosi, Alessia; Cavallini, Elena; Bottiroli, Sara; Bianco, Federica; Lecce, Serena

    2016-01-01

    Previous research on age-related changes in Theory of Mind (ToM) showed a decline in older adults, particularly pronounced over 75 years of age. Evidence that ToM may be enhanced in healthy aging people has been demonstrated, but no study has focused on the role of age on the effects of ToM training for elderly people. The present study was designed to examine the efficacy of a ToM training on practiced (ToM Strange Stories) and transfer tasks (ToM Animations) in both young and older adults. The study involved 127 older adults belonging to two age groups: young-old (Mage = 64.41; SD = 2.49; range: 60-69 years) and old-old (Mage = 75.66; SD = 4.38; range: 70-85 years), randomly assigned to either a ToM group or a control group condition. All participants took part in two 2-hour testing sessions and four 2-hour training sessions. Results showed that both young-old and old-old adults in the ToM group condition improved their ability to reason on complex-mental states significantly more than participants in the control group condition. This positive effect of the training was evident on practiced and transfer ToM tasks. Crucially, age did not moderate the effect of the ToM training. These findings demonstrate that young-old and old-old adults equally benefit from the ToM training. Implications for the positive effect of the ToM training in old-old adults are discussed.

  19. Theory of mind in middle childhood: Longitudinal associations with executive function and social competence.

    Science.gov (United States)

    Devine, Rory T; White, Naomi; Ensor, Rosie; Hughes, Claire

    2016-05-01

    The vast majority of studies on theory of mind (ToM) have focused on the preschool years. Extending the developmental scope of ToM research presents opportunities to both reassess theoretical accounts of ToM and test its predictive utility. The twin aims of this longitudinal study were to examine developmental relations between ToM, executive function (EF), and teacher-rated social competence in middle childhood. One hundred thirty-seven children (69 males) were followed across a 4-year period spanning middle childhood (M ages at Waves 1 and 2 = 6.05, SD = .35, and 10.81, SD = .35, respectively). Individual differences in ToM were moderately stable across middle childhood. Although there were concurrent associations between ToM and EF at both time points, there were no longitudinal links between these constructs. In contrast, there were concurrent and longitudinal links between ToM and teacher-rated social competence, such that individual differences in ToM predicted later social competence at school. These results are discussed in light of competing theories about the links between ToM and EF and the importance of individual differences in ToM for children's social lives. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  20. Deficits in theory of mind and social anxiety as independent paths to paranoid features in schizophrenia.

    Science.gov (United States)

    Lysaker, Paul H; Salvatore, Giampaolo; Grant, Megan L A; Procacci, Michele; Olesek, Kyle L; Buck, Kelly D; Nicolò, Giuseppe; Dimaggio, Giancarlo

    2010-12-01

    Research suggests paranoia among persons with schizophrenia may be the result of a number of different psychological processes including deficits in theory of mind (ToM) and social anxiety. To test this hypothesis, this study sought to determine whether a group of highly paranoid persons with and without a ToM deficit could be detected and whether the group with paranoia and better ToM might have high levels of social anxiety. To explore this, a cluster analysis was performed on a group of 102 adults with schizophrenia spectrum disorders in a non-acute phase of illness on the basis of ratings of paranoid features using the Positive and Negative Syndrome Scale and levels of ToM deficit using a factor score which summarized four different ToM assessments. Four groups were produced: High Paranoia/Poor ToM (n = 14); Low Paranoia/Good ToM (n = 22); Low Paranoia/Low Middle ToM (n=29); and High Paranoia/High Middle ToM (n = 23). Groups were then compared on self report of social anxiety. As predicted, the group with levels of high paranoid features and relatively better ToM performance had significantly higher levels of social anxiety than all other groups. Published by Elsevier B.V.

  1. Social neuroscience and theory of mind.

    Science.gov (United States)

    Westby, Carol E

    2014-01-01

    The role of theory of mind (ToM) in autism spectrum disorders and other communication impairments has been an active area of research in the last 30 years. Advances in neuroimaging in the last 10 years have led to the rise of the field of social neuroscience, which has markedly increased the understanding of the neurophysiological/neuroanatomical and neurochemical nature of ToM functioning and deficits in typically developing individuals and in children and adults with a variety of social and communication impairments. The goal of this paper is to (a) describe the current concepts of ToM based on neuroscience research, and (b) present a framework for the dimensions of ToM that have been identified, which can be used to guide assessment and intervention for persons with deficits in ToM that affect social interactions. This article presents neuroscience research that has documented the neurophysiological/neuroanatomical bases for cognitive and affective ToM and interpersonal and intrapersonal ToM as well as neurochemical and epigenetic influences on ToM. This information provides an important framework for assessing ToM deficits in persons with social and communication impairments and developing interventions that target the specific dimensions of ToM deficits. © 2014 S. Karger AG, Basel.

  2. Theory of mind in schizophrenia: error types and associations with symptoms.

    Science.gov (United States)

    Fretland, Ragnhild A; Andersson, Stein; Sundet, Kjetil; Andreassen, Ole A; Melle, Ingrid; Vaskinn, Anja

    2015-03-01

    Social cognition is an important determinant of functioning in schizophrenia. However, how social cognition relates to the clinical symptoms of schizophrenia is still unclear. The aim of this study was to explore the relationship between a social cognition domain, Theory of Mind (ToM), and the clinical symptoms of schizophrenia. Specifically, we investigated the associations between three ToM error types; 1) "overmentalizing" 2) "reduced ToM and 3) "no ToM", and positive, negative and disorganized symptoms. Fifty-two participants with a diagnosis of schizophrenia or schizoaffective disorder were assessed with the Movie for the Assessment of Social Cognition (MASC), a video-based ToM measure. An empirically validated five-factor model of the Positive and Negative Syndrome Scale (PANSS) was used to assess clinical symptoms. There was a significant, small-moderate association between overmentalizing and positive symptoms (rho=.28, p=.04). Disorganized symptoms correlated at a trend level with "reduced ToM" (rho=.27, p=.05). There were no other significant correlations between ToM impairments and symptom levels. Positive/disorganized symptoms did not contribute significantly in explaining total ToM performance, whereas IQ did (B=.37, p=.01). Within the undermentalizing domain, participants performed more "reduced ToM" errors than "no ToM" errors. Overmentalizing was associated with positive symptoms. The undermentalizing error types were unrelated to symptoms, but "reduced ToM" was somewhat associated to disorganization. The higher number of "reduced ToM" responses suggests that schizophrenia is characterized by accuracy problems rather than a fundamental lack of mental state concept. The findings call for the use of more sensitive measures when investigating ToM in schizophrenia to avoid the "right/wrong ToM"-dichotomy. Copyright © 2015 Elsevier B.V. All rights reserved.

  3. Putting theory of mind in its place: psychological explanations of the socio-emotional-communicative impairments in autistic spectrum disorder.

    Science.gov (United States)

    Boucher, Jill

    2012-05-01

    In this review, the history of the theory of mind (ToM) theory of autistic spectrum disorder (ASD) is outlined (in which ToM is indexed by success on false belief tasks), and the explanatory power and psychological causes of impaired ToM in ASD are critically discussed. It is concluded that impaired ToM by itself has only limited explanatory power, but that explorations of the psychological precursors of impaired ToM have been fruitful in increasing understanding of mindreading impairments in ASD (where 'mindreading' refers those abilities that underlie triadic interaction as well as ToM). It is argued that early explanations of impaired mindreading are untenable for various reasons, but that impairments of dyadic interaction in ASD that could lead to impaired ability to represent others' mental states may be the critical psychological cause, or causes, of impaired ToM. The complexity of causal routes to impaired ToM is emphasized.

  4. Oracle Corporation 1-2

    CERN Multimedia

    CERN. Geneva

    2005-01-01

    During these sessions, Tom Kyte of Oracle Corporation will cover the following topics:# The Tools Tom uses, # The Top 5 things done wrong over and over again, # Building test cases, # Oracle 10g "cool features" Speaker Bio:Tom Kyte is the Vice President, Core Technologies for Oracle Government, Education and Healthcare. Before starting at Oracle, Tom Kyte worked as a systems integrator building large-scale, heterogeneous databases and applications, mostly for military and government customers. He spends a great deal of his time working with the Oracle database and, more specifically, working with people who are working with the Oracle database. Tom Kyte is the Tom behind the AskTom web site, answering people's questions about the Oracle database and its tools (http://asktom.oracle.com/). He is also the author of the AskTom column in http://www.oracle.com/technology/oramag/oracle/current.html Oracle Magazine, and the author of Expert One-on-One Oracle (Apress, 2003), Beginning Oracle Programming (Wrox Press, 2...

  5. HYDRA Hyperspectral Data Research Application Tom Rink and Tom Whittaker

    Science.gov (United States)

    Rink, T.; Whittaker, T.

    2005-12-01

    HYDRA is a freely available, easy to install tool for visualization and analysis of large local or remote hyper/multi-spectral datasets. HYDRA is implemented on top of the open source VisAD Java library via Jython - the Java implementation of the user friendly Python programming language. VisAD provides data integration, through its generalized data model, user-display interaction and display rendering. Jython has an easy to read, concise, scripting-like, syntax which eases software development. HYDRA allows data sharing of large datasets through its support of the OpenDAP and OpenADDE server-client protocols. The users can explore and interrogate data, and subset in physical and/or spectral space to isolate key areas of interest for further analysis without having to download an entire dataset. It also has an extensible data input architecture to recognize new instruments and understand different local file formats, currently NetCDF and HDF4 are supported.

  6. Theory of mind deficit in bipolar disorder: is it related to a previous history of psychotic symptoms?

    Science.gov (United States)

    Lahera, Guillermo; Montes, José Manuel; Benito, Adolfo; Valdivia, María; Medina, Elena; Mirapeix, Isabel; Sáiz-Ruiz, Jerónimo

    2008-12-15

    It has been hypothesized that a Theory of Mind (ToM) deficit could be a vulnerability marker for psychosis. Recent studies, however, have shown ToM deficits in affective relapses of bipolar disorder as well as in the euthymic phase. This study analyzes the relationship between ToM and a previous history of psychotic symptoms in bipolar disorder. ToM, sustained attention and executive functions were analyzed in 75 bipolar euthymic patients with three or more previous relapses (42 of them had a history of psychotic symptoms and 33 did not) and 48 healthy subjects. ToM was assessed with the Advanced Test by Happé. ToM performance was similar in bipolar patients with or without a history of psychotic symptoms, and in both cases it was significantly reduced as compared with the healthy control group. Similarly, both bipolar groups showed impaired sustained attention and executive functions. This general cognitive deficit partially explains the differences obtained in ToM. The ToM instrument used shows low sensitivity for assessing ToM in bipolar patients and it could partially reflect general cognitive functioning rather than a specific deficit in psychosis. ToM deficit is not a trait marker for psychosis, given that it is present in bipolar disorder regardless of a previous history of psychotic symptoms.

  7. Neural responses to affective and cognitive theory of mind in children and adolescents with autism spectrum disorder.

    Science.gov (United States)

    Kim, Eunjoo; Kyeong, Sunghyon; Cheon, Keun-Ah; Park, Bumhee; Oh, Maeng-Keun; Chun, Ji Won; Park, Hae-Jeong; Kim, Jae-Jin; Song, Dong-Ho

    2016-05-16

    Children and adolescents with Autism Spectrum Disorder (ASD) are characterized by an impaired Theory of Mind (ToM). Recent evidence suggested that two aspects of ToM (cognitive ToM versus affective ToM) are differentially impaired in individuals with ASD. In this study, we examined the neural correlates of cognitive and affective ToM in children and adolescents with ASD compared to typically developing children (TDCs). Twelve children and adolescents with ASD and 12 age, IQ matched TDCs participated in this functional MRI study. The ToM task involved the attribution of cognitive and affective mental states to a cartoon character based on verbal and eye-gaze cues. In cognitive ToM tasks, ASD participants recruited the medial prefrontal cortex (mPFC), anterior cingulate cortex (ACC), and superior temporal gyrus (STG) to a greater extent than did TDCs. In affective ToM tasks, both ASD and TDC participants showed more activation in the insula and other subcortical regions than in cognitive ToM tasks. Correlational analysis revealed that greater activation of the mPFC/ACC regions was associated with less symptom severity in ASD patients. In sum, our study suggests that the recruitment of additional prefrontal resources can compensate for the successful behavioral performance in the ToM task in ASD participants. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  8. The Children's Social Understanding Scale: construction and validation of a parent-report measure for assessing individual differences in children's theories of mind.

    Science.gov (United States)

    Tahiroglu, Deniz; Moses, Louis J; Carlson, Stephanie M; Mahy, Caitlin E V; Olofson, Eric L; Sabbagh, Mark A

    2014-11-01

    Children's theory of mind (ToM) is typically measured with laboratory assessments of performance. Although these measures have generated a wealth of informative data concerning developmental progressions in ToM, they may be less useful as the sole source of information about individual differences in ToM and their relation to other facets of development. In the current research, we aimed to expand the repertoire of methods available for measuring ToM by developing and validating a parent-report ToM measure: the Children's Social Understanding Scale (CSUS). We present 3 studies assessing the psychometric properties of the CSUS. Study 1 describes item analysis, internal consistency, test-retest reliability, and relation of the scale to children's performance on laboratory ToM tasks. Study 2 presents cross-validation data for the scale in a different sample of preschool children with a different set of ToM tasks. Study 3 presents further validation data for the scale with a slightly older age group and a more advanced ToM task, while controlling for several other relevant cognitive abilities. The findings indicate that the CSUS is a reliable and valid measure of individual differences in children's ToM that may be of great value as a complement to standard ToM tasks in many different research contexts. (PsycINFO Database Record (c) 2014 APA, all rights reserved).

  9. Theory of Mind intervention for outpatients with schizophrenia.

    Science.gov (United States)

    Bechi, Margherita; Spangaro, Marco; Bosia, Marta; Zanoletti, Andrea; Fresi, Francesco; Buonocore, Mariachiara; Cocchi, Federica; Guglielmino, Carmelo; Smeraldi, Enrico; Cavallaro, Roberto

    2013-01-01

    Social disability is one of the critical areas known to be a predictor of daily functioning in schizophrenia. Recent studies showed that impairments in Theory of Mind (ToM) contribute to real-world social functioning and are more strongly associated with community outcomes than other neuropsychological domains of cognition. Several experiments revealed an improving potential of social cognition targeted training, particularly through introduction of verbalisation and explicit manipulation of information about others' mental states. Based on these data, we evaluated longitudinally, with a controlled trial, the feasibility and efficacy of ToM training and the possible influences of daily functioning and IQ on the enhancement of ToM abilities. Thirty outpatients with schizophrenia were recruited and randomly allocated to two groups: ToM Intervention (ToMI), based on verbalisation of selected comic strips representing ToM scenarios, or active control group (ACG). Results showed a significant improvement of ToM abilities among subjects allocated to ToMI compared to ACG, confirming the hypothesis of the enhancing potential of training methods targeting ToM functions. Moreover, we observed no influences of neuropsychological and functional variables on ToM improvement. Development of future studies should take into account possible effects of ToM training on functional outcome, according to the strong associations between ToM abilities and real-world social functioning.

  10. Enfermedad de Tomás en el sector salud pinareño Tomas's disease in Pinar del Rio health sector

    Directory of Open Access Journals (Sweden)

    Lidia Rosa Salgueiro Labrador

    2012-10-01

    Full Text Available Introducción: médicos, pacientes y sociedad precisan del desarrollo armónico de una ética contemporánea que responda a las exigencias de las nuevas relaciones que el desarrollo científico-técnico y cultural impone, al influjo de las profundas transformaciones socioeconómicas y políticas a que el presente siglo reta. Objetivo: determinar la influencia de la Enfermedad de Tomás o síndrome de Burn-out en cinco policlínicos y dos clínicas estomatológicas de Pinar del Río y Consolación del Sur en el mes de marzo del año 2011. Material y Método: se realizó una investigación descriptiva, en opinión de 234 profesionales encuestados y aplicó una encuesta compuesta de cinco preguntas con cinco opciones para seleccionar la más aceptable. Los resultados se procesaron por la estadística descriptiva determinando frecuencias absolutas y relativas que se presentan en tablas. Resultados: el estudio constató que las respuestas relacionan los problemas actuales, a la crisis de valores entre los profesionales, en un 64,5% de las respuestas; más del 50% opinan que la crisis es evitable en parte, recomiendan mejorar condiciones salariales para reforzar motivaciones, en más de las tres quintas partes y el 32% consideran que debe mejorar la formación humanista y perfeccionar la organización de los servicios. El 45,7% considera que la relación usuario-paciente-institución tiene imperfecciones en su organización y recomiendan prestar más atención a la discusión colectiva de los problemas e incentivar el reforzamiento de valores entre los trabajadores del sector, sumando más del 70% las respuestas. Conclusiones: a pesar de que se percibe la desmotivación que caracteriza la enfermedad de Tomás, el mal es prevenible por la confianza en los profesionales y la voluntad política que orienta el trabajo en salud hacia la excelencia.Introduction: medical doctors, patients and society require the harmonic development of a contemporaneous

  11. [Theory of mind in schizophrenia spectrum disorders].

    Science.gov (United States)

    Bora, Emre

    2009-01-01

    To review studies that investigated theory of mind (ToM) deficits in schizophrenia spectrum disorders. After a thorough literature search, 71 studies were included in this review. Data regarding the relationship between ToM, and other cognitive skills, symptoms, and the impact of the state of illness were reviewed. ToM instruments used in schizophrenia spectrum disorders have some major psychometric limitations; however, previous research was still able to provide some important findings regarding mentalizing impairments in schizophrenia. While ToM deficits are more pronounced in the acute phase of illness, it seems to persist during periods of remission. There is also evidence of ToM deficits in the healthy relatives of schizophrenics, patients with delusional disorder and bipolar disorder (BD), and individuals with high schizotypy scores. ToM dysfunction might be secondary to other cognitive deficits in patients with schizophrenia that have a good prognosis, asymptomatic schizophrenia, delusional disorder, and BD. Other cognitive deficits do not seem to explain ToM dysfunction in patients with psychosis and severe negative symptoms. These findings support the contribution of impairment in both domain-general and domain-specific mechanisms to ToM deficits in schizophrenia spectrum disorders. ToM deficits may be important for understanding poor social functioning and poor insight in psychotic disorders. While ToM is influenced by state variables, it might be an endophenotype of schizophrenia; however, ToM is likely to be an indicator of other frontal lobe-related endophenotypes. Longitudinal studies conducted with high-risk individuals are particularly important.

  12. Non-linearities in Theory-of-Mind Development.

    Science.gov (United States)

    Blijd-Hoogewys, Els M A; van Geert, Paul L C

    2016-01-01

    Research on Theory-of-Mind (ToM) has mainly focused on ages of core ToM development. This article follows a quantitative approach focusing on the level of ToM understanding on a measurement scale, the ToM Storybooks, in 324 typically developing children between 3 and 11 years of age. It deals with the eventual occurrence of developmental non-linearities in ToM functioning, using smoothing techniques, dynamic growth model building and additional indicators, namely moving skewness, moving growth rate changes and moving variability. The ToM sum-scores showed an overall developmental trend that leveled off toward the age of 10 years. Within this overall trend two non-linearities in the group-based change pattern were found: a plateau at the age of around 56 months and a dip at the age of 72-78 months. These temporary regressions in ToM sum-score were accompanied by a decrease in growth rate and variability, and a change in skewness of the ToM data, all suggesting a developmental shift in ToM understanding. The temporary decreases also occurred in the different ToM sub-scores and most clearly so in the core ToM component of beliefs. It was also found that girls had an earlier growth spurt than boys and that the underlying developmental path was more salient in girls than in boys. The consequences of these findings are discussed from various theoretical points of view, with an emphasis on a dynamic systems interpretation of the underlying developmental paths.

  13. Theory of mind reasoning in schizophrenia patients and non-psychotic relatives.

    Science.gov (United States)

    Cassetta, Briana; Goghari, Vina

    2014-08-15

    Research consistently demonstrates that schizophrenia patients have theory of mind (ToM) impairments. Additionally, there is some evidence that family members of schizophrenia patients also demonstrate impairments in ToM, suggesting a genetic vulnerability for the disorder. This study assessed ToM abilities (i.e., sarcasm comprehension) in schizophrenia patients and their first-degree biological relatives during video-taped social interactions, to be representative of real-world interactions and to assess for disease-specific and/or genetic liability effects. Additionally, we assessed whether ToM abilities predicted social and global functioning in schizophrenia patients, and whether symptoms were associated with ToM deficits. Schizophrenia patients demonstrated impairments in sarcasm comprehension compared to controls and relatives, whereas relatives showed intact comprehension. Symptoms of schizophrenia significantly predicted worse ToM abilities. Furthermore, in schizophrenia patients, impaired ToM reasoning predicted worse social and global functioning. Given schizophrenia patients demonstrated impairments in ToM reasoning in a task that resembles real-life interactions, this might be a key area for remediation. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  14. Theory of Mind and Reading Comprehension in Deaf and Hard-of-Hearing Signing Children

    Science.gov (United States)

    Holmer, Emil; Heimann, Mikael; Rudner, Mary

    2016-01-01

    Theory of Mind (ToM) is related to reading comprehension in hearing children. In the present study, we investigated progression in ToM in Swedish deaf and hard-of-hearing (DHH) signing children who were learning to read, as well as the association of ToM with reading comprehension. Thirteen children at Swedish state primary schools for DHH children performed a Swedish Sign Language (SSL) version of the Wellman and Liu (2004) ToM scale, along with tests of reading comprehension, SSL comprehension, and working memory. Results indicated that ToM progression did not differ from that reported in previous studies, although ToM development was delayed despite age-appropriate sign language skills. Correlation analysis revealed that ToM was associated with reading comprehension and working memory, but not sign language comprehension. We propose that some factor not investigated in the present study, possibly represented by inference making constrained by working memory capacity, supports both ToM and reading comprehension and may thus explain the results observed in the present study. PMID:27375532

  15. Theory of Mind and Reading Comprehension in Deaf and Hard-of-Hearing Signing Children.

    Science.gov (United States)

    Holmer, Emil; Heimann, Mikael; Rudner, Mary

    2016-01-01

    Theory of Mind (ToM) is related to reading comprehension in hearing children. In the present study, we investigated progression in ToM in Swedish deaf and hard-of-hearing (DHH) signing children who were learning to read, as well as the association of ToM with reading comprehension. Thirteen children at Swedish state primary schools for DHH children performed a Swedish Sign Language (SSL) version of the Wellman and Liu (2004) ToM scale, along with tests of reading comprehension, SSL comprehension, and working memory. Results indicated that ToM progression did not differ from that reported in previous studies, although ToM development was delayed despite age-appropriate sign language skills. Correlation analysis revealed that ToM was associated with reading comprehension and working memory, but not sign language comprehension. We propose that some factor not investigated in the present study, possibly represented by inference making constrained by working memory capacity, supports both ToM and reading comprehension and may thus explain the results observed in the present study.

  16. Theory of mind and specific language impairment in school-age children.

    Science.gov (United States)

    Spanoudis, George

    2016-01-01

    Research on the relationship between aspects of language development and Theory of Mind (ToM) in children with language impairments suggests that children with language impairment show a delay in ToM development. This study aimed to examine the relationships of the syntactic, semantic, and pragmatic skills with ToM in school-age children. Twenty children with Specific Language Impairment (SLI) aged 9-12 years and two control groups, one matched for chronological age (CA) and one for language ability (LA) (aged 8-10 years) were compared on a set of language tasks tapping syntactic, semantic, and pragmatic skills and on an advanced test of ToM. Results showed that children with SLI performed poorly on the ToM task compared to the CA matches. Also, analysis showed that language skills and ToM are related and that syntactic and pragmatic abilities contributed significantly to the prediction of ToM performance in the SLI group. It is concluded that the syntax/pragmatic aspects of the language impact on ToM understanding in children with SLI. Copyright © 2016 Elsevier Inc. All rights reserved.

  17. The influence of inhibitory processes on affective theory of mind in young and old adults.

    Science.gov (United States)

    Mahy, Caitlin E V; Vetter, Nora; Kühn-Popp, Nina; Löcher, Carolin; Krautschuk, Susan; Kliegel, Matthias

    2014-01-01

    The primary aim of this study was to examine the impact of an inhibition manipulation on the effect of age on theory of mind (ToM) in an ecologically valid, affective ToM task. Participants were 30 young and 30 old adults. The Cambridge Mindreading Face-Voice Battery was used to measure ToM; in addition, measures of fluid and crystallized intelligence were taken. Participants were subjected to three levels of inhibitory demand during ToM reasoning: emotional inhibition, non-emotional inhibition, and no inhibition. Old adults performed worse than young adults. The emotional and non-emotional inhibition conditions resulted in worse ToM performance compared to the no inhibition condition. There were no differences in the impact of the inhibition conditions on old and young adults. Regression analyses suggested that old adults' crystallized intelligence was a significant predictor of ToM performance, whereas it did not predict young adults' ToM performance. Results are discussed in terms of verbal ability as a possible compensatory mechanism in coping with verbal inhibitory load in ToM reasoning.

  18. The Role of Theory of Mind on Social Information Processing in Children With Autism Spectrum Disorders: A Mediation Analysis.

    Science.gov (United States)

    Mazza, Monica; Mariano, Melania; Peretti, Sara; Masedu, Francesco; Pino, Maria Chiara; Valenti, Marco

    2017-05-01

    Individuals with autism spectrum disorders (ASD) show significant impairments in social skills and theory of mind (ToM). The aim of this study was to evaluate ToM and social information processing abilities in 52 children with ASD compared to 55 typically developing (TD) children. A mediation analysis evaluated whether social information processing abilities can be mediated by ToM competences. In our results, children with autism showed a deficit in social skills and ToM components. The innovative results of our study applying mediation analysis demonstrate that ToM plays a key role in the development of social abilities, and the lack of ToM competences in children with autism impairs their competent social behavior.

  19. Visualization of cytolytic T cell differentiation and granule exocytosis with T cells from mice expressing active fluorescent granzyme B.

    Directory of Open Access Journals (Sweden)

    Pierre Mouchacca

    Full Text Available To evaluate acquisition and activation of cytolytic functions during immune responses we generated knock in (KI mice expressing Granzyme B (GZMB as a fusion protein with red fluorescent tdTomato (GZMB-Tom. As for GZMB in wild type (WT lymphocytes, GZMB-Tom was absent from naïve CD8 and CD4 T cells in GZMB-Tom-KI mice. It was rapidly induced in most CD8 T cells and in a subpopulation of CD4 T cells in response to stimulation with antibodies to CD3/CD28. A fraction of splenic NK cells expressed GZMB-Tom ex vivo with most becoming positive upon culture in IL-2. GZMB-Tom was present in CTL granules and active as a protease when these degranulated into cognate target cells, as shown with target cells expressing a specific FRET reporter construct. Using T cells from mice expressing GZMB-Tom but lacking perforin, we show that the transfer of fluorescent GZMB-Tom into target cells was dependent on perforin, favoring a role for perforin in delivery of GZMB at the target cells' plasma membranes. Time-lapse video microscopy showed Ca++ signaling in CTL upon interaction with cognate targets, followed by relocalization of GZMB-Tom-containing granules to the synaptic contact zone. A perforin-dependent step was next visualized by the fluorescence signal from the non-permeant dye TO-PRO-3 at the synaptic cleft, minutes before the labeling of the target cell nucleus, characterizing a previously undescribed synaptic event in CTL cytolysis. Transferred OVA-specific GZMB-Tom-expressing CD8 T cells acquired GZMB-Tom expression in Listeria monocytogenes-OVA infected mice as soon as 48h after infection. These GZMB-Tom positive CD8 T cells localized in the splenic T-zone where they interacted with CD11c positive dendritic cells (DC, as shown by GZMB-Tom granule redistribution to the T/DC contact zone. GZMB-Tom-KI mice thus also provide tools to visualize acquisition and activation of cytolytic function in vivo.

  20. The mirror-neuron system and observational learning: Implications for the effectiveness of dynamic visualizations.

    OpenAIRE

    Van Gog, Tamara; Paas, Fred; Marcus, Nadine; Ayres, Paul; Sweller, John

    2009-01-01

    Van Gog, T., Paas, F., Marcus, N., Ayres, P., & Sweller, J. (2009). The mirror-neuron system and observational learning: Implications for the effectiveness of dynamic visualizations. Educational Psychology Review, 21, 21-30.

  1. Integration of technology-based outcome measures in clinical trials of Parkinson and other neurodegenerative diseases.

    Science.gov (United States)

    Artusi, Carlo Alberto; Mishra, Murli; Latimer, Patricia; Vizcarra, Joaquin A; Lopiano, Leonardo; Maetzler, Walter; Merola, Aristide; Espay, Alberto J

    2018-01-01

    We sought to review the landscape of past, present, and future use of technology-based outcome measures (TOMs) in clinical trials of neurodegenerative disorders. We systematically reviewed PubMed and ClinicalTrials.gov for published and ongoing clinical trials in neurodegenerative disorders employing TOMs. In addition, medical directors of selected pharmaceutical companies were surveyed on their companies' ongoing efforts and future plans to integrate TOMs in clinical trials as primary, secondary, or exploratory endpoints. We identified 164 published clinical trials indexed in PubMed that used TOMs as outcome measures in Parkinson disease (n = 132) or other neurodegenerative disorders (n = 32). The ClinicalTrials.gov search yielded 42 clinical trials using TOMs, representing 2.7% of ongoing trials. Sensor-based technology accounted for over 75% of TOMs applied. Gait and physical activity were the most common targeted domains. Within the next 5 years, 83% of surveyed pharmaceutical companies engaged in neurodegenerative disorders plan to deploy TOMs in clinical trials. Although promising, TOMs are underutilized in clinical trials of neurodegenerative disorders. Validating relevant endpoints, standardizing measures and procedures, establishing a single platform for integration of data and algorithms from different devices, and facilitating regulatory approvals should advance TOMs integration into clinical trials. Copyright © 2017 Elsevier Ltd. All rights reserved.

  2. Evidence from paranoid schizophrenia for more than one component of theory of mind

    Science.gov (United States)

    Scherzer, Peter; Achim, André; Léveillé, Edith; Boisseau, Emilie; Stip, Emmanuel

    2015-01-01

    We previously reported finding that performance was impaired on four out of five theory of mind (ToM) tests in a group of 21 individuals diagnosed with paranoid schizophrenia (pScz), relative to a non-clinical group of 29 individuals (Scherzer et al., 2012). Only the Reading the Mind in the Eyes Test did not distinguish between groups. A principal components analysis revealed that the results on the ToM battery could be explained by one general ToM factor with the possibility of a latent second factor. As well, the tests were not equally sensitive to the pathology. There was also overmentalization in some ToM tests and under-mentalisation in others. These results led us to postulate that there is more than one component to ToM. We hypothesized that correlations between the different EF measures and ToM tests would differ sufficiently within and between groups to support this hypothesis. We considered the relationship between the performance on eight EF tests and five ToM tests in the same diagnosed and non-clinical individuals as in the first study. The ToM tests shared few EF correlates and each had its own best EF predictor. These findings support the hypothesis of multiple ToM components. PMID:26579026

  3. Theory of mind correlates with clinical insight but not cognitive insight in patients with schizophrenia.

    Science.gov (United States)

    Zhang, Qi; Li, Xu; Parker, Giverny J; Hong, Xiao-Hong; Wang, Yi; Lui, Simon S Y; Neumann, David L; Cheung, Eric F C; Shum, David H K; Chan, Raymond C K

    2016-03-30

    Research on the relationship between insight and social cognition, in particular Theory of Mind (ToM), in schizophrenia has yielded mixed findings to date. Very few studies, however, have assessed both clinical insight and cognitive insight when examining their relationships with ToM in schizophrenia. The current study thus investigated the relationship between clinical insight, cognitive insight, and ToM in a sample of 56 patients with schizophrenia and 30 healthy controls. Twenty-seven patients were classified as low in clinical insight according to their scores on the 'insight' item (G12) of the Positive and Negative Syndrome Scale (PANSS). Moreover, cognitive insight and ToM were assessed with the Beck Cognitive Insight Scale (BCIS) and the Yoni task, respectively. The results indicated that patients with poor clinical insight performed worse on tasks of second-order cognitive and affective ToM, while the ToM performance of patients with high clinical insight was equivalent to that of healthy controls. Furthermore, while clinical insight was correlated with ToM and clinical symptoms, cognitive insight did not correlate with clinical insight, ToM, or clinical symptoms. Clinical insight thus appears to be an important factor related to ToM in schizophrenia. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  4. Reading wild minds: A computational assay of Theory of Mind sophistication across seven primate species.

    Directory of Open Access Journals (Sweden)

    Marie Devaine

    2017-11-01

    Full Text Available Theory of Mind (ToM, i.e. the ability to understand others' mental states, endows humans with highly adaptive social skills such as teaching or deceiving. Candidate evolutionary explanations have been proposed for the unique sophistication of human ToM among primates. For example, the Machiavellian intelligence hypothesis states that the increasing complexity of social networks may have induced a demand for sophisticated ToM. This type of scenario ignores neurocognitive constraints that may eventually be crucial limiting factors for ToM evolution. In contradistinction, the cognitive scaffolding hypothesis asserts that a species' opportunity to develop sophisticated ToM is mostly determined by its general cognitive capacity (on which ToM is scaffolded. However, the actual relationships between ToM sophistication and either brain volume (a proxy for general cognitive capacity or social group size (a proxy for social network complexity are unclear. Here, we let 39 individuals sampled from seven non-human primate species (lemurs, macaques, mangabeys, orangutans, gorillas and chimpanzees engage in simple dyadic games against artificial ToM players (via a familiar human caregiver. Using computational analyses of primates' choice sequences, we found that the probability of exhibiting a ToM-compatible learning style is mainly driven by species' brain volume (rather than by social group size. Moreover, primates' social cognitive sophistication culminates in a precursor form of ToM, which still falls short of human fully-developed ToM abilities.

  5. Gene-environment interaction between the oxytocin receptor (OXTR) gene and parenting behaviour on children's theory of mind.

    Science.gov (United States)

    Wade, Mark; Hoffmann, Thomas J; Jenkins, Jennifer M

    2015-12-01

    Theory of mind (ToM) is the ability to interpret and understand human behaviour by representing the mental states of others. Like many human capacities, ToM is thought to develop through both complex biological and socialization mechanisms. However, no study has examined the joint effect of genetic and environmental influences on ToM. This study examined how variability in the oxytocin receptor gene (OXTR) and parenting behavior--two widely studied factors in ToM development-interacted to predict ToM in pre-school-aged children. Participants were 301 children who were part of an ongoing longitudinal birth cohort study. ToM was assessed at age 4.5 using a previously validated scale. Parenting was assessed through observations of mothers' cognitively sensitive behaviours. Using a family-based association design, it was suggestive that a particular variant (rs11131149) interacted with maternal cognitive sensitivity on children's ToM (P = 0.019). More copies of the major allele were associated with higher ToM as a function of increasing cognitive sensitivity. A sizeable 26% of the variability in ToM was accounted for by this interaction. This study provides the first empirical evidence of gene-environment interactions on ToM, supporting the notion that genetic factors may be modulated by potent environmental influences early in development. © The Author (2015). Published by Oxford University Press. For Permissions, please email: journals.permissions@oup.com.

  6. Performances on a cognitive theory of mind task: specific decline or general cognitive deficits? Evidence from normal aging.

    Science.gov (United States)

    Fliss, Rafika; Lemerre, Marion; Mollard, Audrey

    2016-06-01

    Compromised theory of mind (ToM) can be explained either by a failure to implement specific representational capacities (mental state representations) or by more general executive selection demands. In older adult populations, evidence supporting affected executive functioning and cognitive ToM in normal aging are reported. However, links between these two functions remain unclear. In the present paper, we address these shortcomings by using a specific task of ToM and classical executive tasks. We studied, using an original cognitive ToM task, the effect of age on ToM performances, in link with the progressive executive decline. 96 elderly participants were recruited. They were asked to perform a cognitive ToM task, and 5 executive tests (Stroop test and Hayling Sentence Completion Test to appreciate inhibitory process, Trail Making Test and Verbal Fluency for shifting assessment and backward span dedicated to estimate working memory capacity). The results show changes in cognitive ToM performance according to executive demands. Correlational studies indicate a significant relationship between ToM performance and the selected executive measures. Regression analyzes demonstrates that level of vocabulary and age as the best predictors of ToM performance. The results are consistent with the hypothesis that ToM deficits are related to age-related domain-general decline rather than as to a breakdown in specialized representational system. The implications of these findings for the nature of social cognition tests in normal aging are also discussed.

  7. The oxygen-rich pentaerythritol modified multi-walled carbon nanotube as an efficient adsorbent for aqueous removal of alizarin yellow R and alizarin red S

    Science.gov (United States)

    Yang, Jia-Ying; Jiang, Xin-Yu; Jiao, Fei-Peng; Yu, Jin-Gang

    2018-04-01

    A contrastive work on the removal of two organic dyes, alizarin yellow R (AYR) and alizarin red S (ARS), was carried out by utilizing pentaerythritol modified multi-walled carbon nanotubes (ox-MWCNT-PER) as a highly efficient adsorbent. Various characterization methods such as scanning electron microscopy (SEM), thermogravimetric analysis (TGA), Fourier transform infrared (FTIR) spectroscopy, the Brunauer-Emmett-Teller (BET) analysis and X-ray photoelectron spectroscopy (XPS), were applied for revealing the physical and chemical properties of the as-prepared material. In addition, the adsorption kinetics, isotherms and thermodynamic parameters were also discussed. The results showed that the time required to achieve the adsorption equilibrium for both dyes was about 30 min, and the increase in temperature was not favorable to the adsorption process. It was worth noting that the adsorption capacity of ox-MWCNT-PER towards ARS dye was more significant than that towards AYR dye. And the maximum adsorption capacities for ARS and AYR were 257.73 mg g-1 and 45.39 mg g-1, respectively. The possible adsorption mechanism was also proposed, and the synergistic effects of the hydrogen bonding and the π-π electron stacking interactions between the adsorbents and adsorbates both contributed to the adsorption. It could be proposed that the ox-MWCNT-PER nanocomposite might have some positive effects in removing organic dyes from water treatment in the future.

  8. Farklı Hayvan Türlerine Ait Karkas Etlerinin ve Mekanik Sıyrılmış Etlerin, Kimyasal Yapılarına ve SDS-PAGE Yardımıyla Saptanan Protein Profillerine Göre Belirlenmesi

    Directory of Open Access Journals (Sweden)

    Ayça Yaralı

    2015-02-01

    Full Text Available Bu çalışmada farklı hayvan karkas etleri ve farklı mekanik sıyrılmış etlerinin kimyasal bileşimi, atomik absorbsiyon spektrofotometresi ile mineral madde bileşimi ve SDS­PAGE ile protein bant dizilimi incelenmiştir. Bu yöntemler ile tür ayrımı ve MDM ayrımı yapılmıştır. Özellikle MDM örneklerinin protein, yağ ve kalsiyum içerikleri diğer karkas etlerinden önemli ölçüde farklı olarak bulunmuştur. Karkas örneklerinin sodyum miktarının MDM örnekleriyle karşılaştırıldığında yüksek olduğu gözlenmiştir. Ayrıca, deneye tabi tutulan makro elementler içinde magnezyum içeriğinin düşük değerlerde olduğu gözlenmiştir. SDS­PAGE bant diziliminde myofibriler proteinler ve sarkoplazmik proteinler incelenmiştir. Elektoroforez jellerinin görüntü analizi ve nicel analizi için densitometre cihazı (The Imager BL, Biolab UviTec software kullanılmıştır.

  9. Theory of Mind in Depressive Disorders: A Review of the Literature.

    Science.gov (United States)

    Berecz, Hajnalka; Tényi, Tamás; Herold, Róbert

    Theory of mind (ToM) is the ability to infer the mental states of others in order to understand and predict their behaviour. This ability is thought to be essential to social functioning and interpersonal relationships. As major depression is characterized by considerable social and interpersonal difficulties, exploration of the quality of ToM functioning can be particularly relevant in this and in related disorders. We aim to review the current state of research on ToM in depressive disorders in order to find out the extent to which ToM impairment is associated with these illnesses. An internet database search was carried out to collect all publications on the subject. A total of 32 publications in English met our inclusion criteria: (a) 17 studies on ToM in major depression, (b) 4 studies on ToM in psychotic depression, (c) 3 studies on ToM in dysphoria or mild depression, (d) 4 studies on ToM in euthymic major depression, (e) 2 studies on ToM in chronic versus episodic depression, and (f) 2 studies on ToM in another psychiatric disorder with comorbid major depression. Despite an increased interest in the research of the topic in recent years, no firm conclusions can be drawn, as the reviewed articles present some conflicting results. Acutely depressed patients have been found to be impaired on tasks involving both ToM social-perceptual and social-cognitive components. On the other hand, a number of studies have not reported significant between-group differences between depressed patients and healthy controls or have found minimal differences. Further research is needed in order to confirm and extend these results. © 2016 S. Karger AG, Basel.

  10. Materia orgánica en una laguna de la costa de Sinaloa, México: (I : cuantificación total

    Directory of Open Access Journals (Sweden)

    Guadalupe de la Lanza E

    1980-12-01

    Full Text Available The distribution and variation of total organic matter (TOM during the rainy season, was studied in the sediments of the coastal lagoon of Huizache-Caimanero, Sinaloa. Two well defined areas werw detected: one with more than 9% TOM, NE of the lagoon, and other with less than 9% TOM, SW of the lagoon. An almost homogeneous TOM concentration was found from the surface to 15-20 cm depth of the sediment core. This is probably due to the continuous addition of TOM from the terrestrial and submerged vegetation.

  11. Unlocking the Mystery of Social Deficits in Autism: Theory of Mind as Key

    Science.gov (United States)

    Blacher, Jan

    2007-01-01

    Theory of mind (ToM) is key to the development of one's social skills. Without ToM, children (or adults) cannot understand or infer the thoughts, feelings, or intentions of others. A lack of ToM skills is considered by some to be a core deficit in autism. ToM affects all interpersonal interactions as well as academics, daily living, following…

  12. Putting Theory of Mind in Its Place: Psychological Explanations of the Socio-Emotional-Communicative Impairments in Autistic Spectrum Disorder

    Science.gov (United States)

    Boucher, Jill

    2012-01-01

    In this review, the history of the theory of mind (ToM) theory of autistic spectrum disorder (ASD) is outlined (in which ToM is indexed by success on false belief tasks), and the explanatory power and psychological causes of impaired ToM in ASD are critically discussed. It is concluded that impaired ToM by itself has only limited explanatory…

  13. EPA GHG Certification of Medium- and Heavy-Duty Vehicles: Development of Road Grade Profiles Representative of US Controlled Access Highways

    Energy Technology Data Exchange (ETDEWEB)

    Wood, Eric [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Duran, Adam [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Burton, Evan [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Gonder, Jeffrey [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Kelly, Kenneth [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2015-05-12

    This report includes a detailed comparison of the TomTom national road grade database relative to a local road grade dataset generated by Southwest Research Institute and a national elevation dataset publically available from the U.S. Geological Survey. This analysis concluded that the TomTom national road grade database was a suitable source of road grade data for purposes of this study.

  14. Comprehension of figurative language in Taiwanese children with autism: The role of theory of mind and receptive vocabulary.

    Science.gov (United States)

    Huang, Su-Fen; Oi, Manabu; Taguchi, Aiko

    2015-01-01

    First-order theory of mind (ToM) is necessary for comprehension of metaphors, and second-order ToM is necessary for comprehension of irony. This study investigated the role of ToM and language ability in comprehending figurative language in 50 Taiwanese children with high-functioning autism spectrum disorders (HFASDs) compared with 50 typically developing children. Results showed that the No-ToM HFASDs group performed worse than the first-order ToM HFASDs group and the second-order ToM HFASDs group in comprehension of metaphors, irony, sarcasm and indirect reproach, but not for indirect request. Receptive vocabulary correlated only with metaphor comprehension. The volatility of results seen among studies in terms of the relationship between ToM and figurative language comprehension is discussed.

  15. Theory of mind abilities in young siblings of children with autism.

    Science.gov (United States)

    Shaked, Michal; Gamliel, Ifat; Yirmiya, Nurit

    2006-03-01

    Deficits in theory of mind (ToM), evident in most individuals with autism, have been suggested as a core deficit of autism. ToM difficulties in young siblings of children with autism (SIBS-A) compared to siblings of typically developing children (SIBS-TD) would place the former within the broad phenotype. We examined ToM's possible associations with measures of language, cognition, and daily living skills. Participants comprised 24 SIBS-A and 24 matched SIBSTD aged 4.6 years. They completed the false belief and the strange stories tasks. We also collected measures of verbal and cognitive ability and daily living skills. Non-significant differences emerged between the groups on both ToM tasks. Differences did emerge in within-group associations between ToM ability and receptive language. The conclusion is that SIBS-A show resilience in ToM abilities. Possibly, these deficits are not genetically transferred to siblings, at least as measured in laboratory-based ToM tasks.

  16. Theory of Mind, Social Desirability, and Unlikely Symptom Reporting in Offenders With and Without Psychopathy.

    Science.gov (United States)

    Nentjes, Lieke; Bernstein, David P; Arntz, Arnoud; Slaats, Mariëtte E; Hannemann, Tina

    2015-08-01

    The current study investigated the relationship between psychopathy and theory of mind (ToM), by comparing the performance of nonpsychopathic offenders (n = 40), psychopathic offenders (n = 42), and nonoffender controls (n = 26) on Happé's test of ToM (Happé, 1994). In addition, we investigated whether offenders' ToM skills would moderate the association between the antisocial psychopathy component (Factor 2) and self-presentation (i.e., the tendency to report social desirability and unlikely symptoms). Results showed groups did not differ in ToM performance. As expected though, ToM moderated the association between psychopathy and self-presentation: only for offenders relatively high in ToM, Factor 2 was strongly related to less social desirability and more unlikely symptom reporting. These results could indicate that offenders who are high in both ToM and Factor 2 exaggerate their mental dysfunction to express their need for clinical attention. Results are used to critically evaluate the interpretation of occurrences in which offenders overplay their psychopathology.

  17. Theory of mind network activity is altered in subjects with familial liability for schizophrenia

    Science.gov (United States)

    Mohnke, Sebastian; Erk, Susanne; Schnell, Knut; Romanczuk-Seiferth, Nina; Schmierer, Phöbe; Romund, Lydia; Garbusow, Maria; Wackerhagen, Carolin; Ripke, Stephan; Grimm, Oliver; Haller, Leila; Witt, Stephanie H.; Degenhardt, Franziska; Tost, Heike; Heinz, Andreas; Meyer-Lindenberg, Andreas; Walter, Henrik

    2016-01-01

    As evidenced by a multitude of studies, abnormalities in Theory of Mind (ToM) and its neural processing might constitute an intermediate phenotype of schizophrenia. If so, neural alterations during ToM should be observable in unaffected relatives of patients as well, since they share a considerable amount of genetic risk. While behaviorally, impaired ToM function is confirmed meta-analytically in relatives, evidence on aberrant function of the neural ToM network is sparse and inconclusive. The present study therefore aimed to further explore the neural correlates of ToM in relatives of schizophrenia. About 297 controls and 63 unaffected first-degree relatives of patients with schizophrenia performed a ToM task during functional magnetic resonance imaging. Consistent with the literature relatives exhibited decreased activity of the medial prefrontal cortex. Additionally, increased recruitment of the right middle temporal gyrus and posterior cingulate cortex was found, which was related to subclinical paranoid symptoms in relatives. These results further support decreased medial prefrontal activation during ToM as an intermediate phenotype of genetic risk for schizophrenia. Enhanced recruitment of posterior ToM areas in relatives might indicate inefficiency mechanisms in the presence of genetic risk. PMID:26341902

  18. Relationship between theory of mind and functional independence is mediated by executive function.

    Science.gov (United States)

    Ahmed, Fayeza S; Miller, L Stephen

    2013-06-01

    Theory of mind (ToM) is the ability to comprehend another person's perspective. Although there is much literature of ToM in children, there is a limited and somewhat inconclusive amount of studies examining ToM in a geriatric population. This study examined ToM's relationship to functional independence. Two tests of ToM, tests of executive function, and a measure of functional ability were administered to cognitively intact older adults. Results showed that 1 test of ToM (Strange Stories test) significantly accounted for variance in functional ability, whereas the other did not (Faux Pas test). In addition, Strange Stories test performance was partially driven by a verbal abstraction-based executive function: proverb interpretation. A multiple mediation model was employed to examine whether executive functions explained the relationship between the Strange Stories test and functional ability. Results showed that both the combined and individual indirect effects of the executive function measures mediated the relationship. We argue that, although components of ToM are associated with functional independence, ToM does not appear to account for additional variance in functional independence beyond executive function measures. PsycINFO Database Record (c) 2013 APA, all rights reserved.

  19. Role of theory of mind and executive function in explaining social intelligence: a structural equation modeling approach.

    Science.gov (United States)

    Yeh, Zai-Ting

    2013-01-01

    Social intelligence is the ability to understand others and the social context effectively and thus to interact with people successfully. Research has suggested that the theory of mind (ToM) and executive function may play important roles in explaining social intelligence. The specific aim of the present study was to test with structural equation modeling (SEM) the hypothesis that performance on ToM tasks is more associated with social intelligence in the elderly than is performance on executive functions. One hundred and seventy-seven participants (age 56-96) completed ToM, executive function, and other basic cognition tasks, and were rated with social intelligence scales. The SEM results showed that ToM and executive function were strongly correlated (0.54); however, only the path coefficient from ToM to social intelligence, and not from executive function, was significant (0.37). ToM performance, but not executive function, was strongly correlated with social intelligence among elderly individuals. ToM and executive function might play different roles in social behavior during normal aging; however, based on the present results, it is possible that ToM might play an important role in social intelligence.

  20. Evidence from paranoid schizophrania for more than one component of theory of mind

    Directory of Open Access Journals (Sweden)

    Peter eScherzer

    2015-10-01

    Full Text Available We previously reported finding that performance was impaired on four out of five theory of mind (ToM tests in a group of 21 individuals diagnosed with paranoid schizophrenia (pScz, relative to a non-clinical group of 29 individuals (Scherzer, Léveillé, Achim, Scherzer, Boisseau, & Stip, 2012. Only the Reading the Mind in the Eyes Test (RMET did not distinguish between groups. A principal components analysis revealed that the results on the ToM battery could be explained by one general ToM factor with the possibility of a latent second factor. As well, the tests were not equally sensitive to the pathology. There was also overmentalization in some ToM tests and under-mentalisation in others. These results led us to postulate that there is more than one component to ToM. We hypothesized that correlations between the different EF measures and ToM tests would differ sufficiently within and between groups to support this hypothesis. We considered the relationship between the performance on eight EF tests and five ToM tests in the same diagnosed and non-clinical individuals as in the first study. The ToM test shared few EF correlates and each had its own best EF predictor.. These findings support the hypothesis of multiple ToM components

  1. Parametrik Olmayan Çok Değişkenli Varyans Analizi ve Sağlık Alanında Bir Uygulaması

    OpenAIRE

    PASİN, Özge; ANKARALI, Handan; CANGÜR, Şengül; SUNGUR, Mehmet Ali

    2016-01-01

    Sağlık araştırmalarında, etkenlerin genellikle birbirleriyle ilişkili birden fazla sonucu olabilir. Bu ilişkili sonuçları ayrı analiz etmek 1.Tip hatanın artmasına neden olur. Ancak pratik uygulamalarda veri analizinde sıklıkla bu hata yapılmakta, daha basit, kolay yorumlanabilen tek değişkenli analiz yöntemlerinden yararlanılmaktadır.  Ayrıca sağlık araştırmalarındaki özelliklerin önemli bir bölümü tek değişkenli parametrik modellerin varsayımlarından olan normal dağılım ve varyansların homo...

  2. Kefir Mikroflorası Üzerinde Araştırma

    OpenAIRE

    Erol Ergüllü; Mustafa Üçüncü

    2015-01-01

    Çalışmada, çeşitli yörelerden sağlanmış 7 kefir örneğinin mikroflorası araştırılmış ve elde edilen bulgulara göre, kefir mikroflorasında süt asidi bakterileri (Streptokok ve Laktobasiller) ile mayaların çoğunlukta olduğu belirlenmiştir. Bu bakteri türlerinden her birinin kefir oluşumunda ayrı bir yeri bulunmaktadır. Süt asidi bakterileri sütü pıhtılaştırmakta ve bunlardan bazıları da ayrıca uçucu asitler oluşturarak, kefirin tat ve kokusunun meydana gelmesine katkıda bulunmaktadırlar. Mayalar...

  3. Kefir Mikroflorası Üzerinde Araştırma

    OpenAIRE

    Ergüllü, Erol; Üçüncü, Mustafa

    2014-01-01

      Çalışmada, çeşitli yörelerden sağlanmış 7 kefir örneğinin mikroflorası araştırılmış ve elde edilen bulgulara göre, kefir mikroflorasında süt asidi bakterileri (Streptokok ve Laktobasiller) ile mayaların çoğunlukta olduğu belirlenmiştir. Bu bakteri türlerinden her birinin kefir oluşumunda ayrı bir yeri bulunmaktadır. Süt asidi bakterileri sütü pıhtılaştırmakta ve bunlardan bazıları da ayrıca uçucu asitler oluşturarak, kefirin tat ve kokusunun meydana gelmesine katkıda bulunmaktadırlar. Mayal...

  4. Kefir Mikroflorası Üzerinde Araştırma

    OpenAIRE

    Ergüllü, Erol; Üçüncü, Mustafa

    2015-01-01

      Çalışmada, çeşitli yörelerden sağlanmış 7 kefir örneğinin mikroflorası araştırılmış ve elde edilen bulgulara göre, kefir mikroflorasında süt asidi bakterileri (Streptokok ve Laktobasiller) ile mayaların çoğunlukta olduğu belirlenmiştir. Bu bakteri türlerinden her birinin kefir oluşumunda ayrı bir yeri bulunmaktadır. Süt asidi bakterileri sütü pıhtılaştırmakta ve bunlardan bazıları da ayrıca uçucu asitler oluşturarak, kefirin tat ve kokusunun meydana gelmesine katkıda bulunmaktadırlar. Mayal...

  5. Autistic adolescents show atypical activation of the brain's mentalizing system even without a prior history of mentalizing problems.

    Science.gov (United States)

    White, Sarah J; Frith, Uta; Rellecke, Julian; Al-Noor, Zainab; Gilbert, Sam J

    2014-04-01

    Some autistic children pass classic Theory of Mind (ToM) tasks that others fail, but the significance of this finding is at present unclear. We identified two such groups of primary school age (labelled ToM+ and ToM-) and a matched comparison group of typically developing children (TD). Five years later we tested these participants again on a ToM test battery appropriate for adolescents and conducted an fMRI study with a story based ToM task. We also assessed autistic core symptoms at these two time points. At both times the ToM- group showed more severe social communication impairments than the ToM+ group, and while showing an improvement in mentalizing performance, they continued to show a significant impairment compared to the NT group. Two independent ROI analyses of the BOLD signal showed activation of the mentalizing network including medial prefrontal cortex, posterior cingulate and lateral temporal cortices. Strikingly, both ToM+ and ToM- groups showed very similar patterns of heightened activation in comparison with the NT group. No differences in other brain regions were apparent. Thus, autistic adolescents who do not have a history of mentalizing problems according to our ToM battery showed the same atypical neurophysiological response during mentalizing as children who did have such a history. This finding indicates that heterogeneity at the behavioural level may nevertheless map onto a similar phenotype at the neuro-cognitive level. Copyright © 2013 The Authors. Published by Elsevier Ltd.. All rights reserved.

  6. Culture and the Sequence of Steps in Theory of Mind Development

    Science.gov (United States)

    Shahaeian, Ameneh; Peterson, Candida C.; Slaughter, Virginia; Wellman, Henry M.

    2011-01-01

    To examine cultural contrasts in the ordered sequence of conceptual developments leading to theory of mind (ToM), we compared 135 3- to 6-year-olds (77 Australians; 58 Iranians) on an established 5-step ToM scale (Wellman & Liu, 2004). There was a cross-cultural difference in the sequencing of ToM steps but not in overall rates of ToM mastery.…

  7. The reciprocal relationship between executive function and theory of mind in middle childhood: a one-year longitudinal perspective

    Directory of Open Access Journals (Sweden)

    Gina eAustin

    2014-06-01

    Full Text Available There is robust evidence showing a link between executive function (EF and theory of mind (ToM in 3- to 5-year-olds. However, it is unclear whether this relationship extends to middle childhood. In addition, there has been much discussion about the nature of this relationship. Whereas some authors claim that ToM is needed for EF, others argue that ToM requires EF. To date, however, studies examining the longitudinal relationship between distinct subcomponents of EF (i.e. attention shifting, WM updating, inhibition and ToM in middle childhood are rare.The present study examined 1 the relationship between three EF subcomponents (attention shifting, WM updating, inhibition and ToM in middle childhood, and 2 the longitudinal reciprocal relationships between the EF subcomponents and ToM across a one-year period. EF and ToM measures were assessed experimentally in a sample of 1,657 children (aged 6 to 11 years at time point one (t1 and one year later at time point two (t2.Results showed that the concurrent relationships between all three EF subcomponents and ToM pertained in middle childhood at t1 and t2, respectively, even when age, gender, and fluid intelligence were partialled out. Moreover, cross-lagged structural equation modeling (again, controlling for age, gender, and fluid intelligence, as well as for the earlier levels of the target variables, revealed partial support for the view that early ToM predicts later EF, but stronger evidence for the assumption that early EF predicts later ToM. The latter was found for attention shifting and WM updating, but not for inhibition. This reveals the importance of studying the exact interplay of ToM and EF across childhood development, especially with regard to different EF subcomponents. Most likely, understanding others’ mental states at different levels of perspective-taking requires specific EF subcomponents, suggesting developmental change in the relations between EF and ToM across childhood.

  8. A compreensão da gratidão e teoria da mente em crianças de 5 anos The understanding of gratitude and theory of mind in 5-year-olds

    Directory of Open Access Journals (Sweden)

    Lia Beatriz de Lucca Freitas

    2012-01-01

    Full Text Available Examinaram-se relações entre compreensão da gratidão (GRA e desenvolvimento de uma teoria da mente (TOM com 228 crianças norteamericanas (53% meninas de 5 anos. Testaram-se as seguintes hipóteses: (a não há diferença de sexo em GRA ou TOM, (b as crianças com melhor desempenho nas tarefas de TOM têm melhor GRA, (c TOM é condição necessária para GRA. Utilizaram-se três tarefas para avaliar TOM: consideração da perspectiva visual, crença falsa de primeira e de segunda ordem. Contaram-se às crianças duas histórias sobre gratidão. Avaliou-se GRA a partir de suas respostas a perguntas feitas após a leitura de cada história. As duas primeiras hipóteses foram confirmadas. A hipótese de que TOM seria condição necessária para GRA não encontrou suficiente suporte empírico.We examined relations between the understanding of gratitude (GRA and the development of a theory of mind (TOM. The study was done with 228 5-year-old North American children (53% female. We tested the following hypotheses: (a there are no sex differences in GRA or TOM, (b children who perform better on TOM tasks have better GRA, (c TOM is a necessary condition for GRA. We used three tasks to evaluate TOM: visual perspective taking, first-order false belief, and second-order false belief. The children were read two vignettes about gratitude. GRA was evaluated based on children's responses to questions asked after each vignette was read. The first two hypotheses were supported. The hypothesis that TOM would be a necessary condition for GRA did not receive sufficient empirical support.

  9. The origins of children's metamemory: the role of theory of mind.

    Science.gov (United States)

    Lecce, Serena; Demicheli, Patrizia; Zocchi, Silvia; Palladino, Paola

    2015-03-01

    The relation between preschoolers' theory of mind (ToM) and declarative metamemory (DM) was investigated in two studies. The first study focused on 4-year-old children's (N=106) cognitive and affective ToM and their DM. The data showed a significant association between cognitive (but not affective) ToM and DM, independent of verbal ability, non-verbal ability, and working memory. The second study involved 83 children tested at 4 years 6 months of age (and 6 months later) for cognitive ToM and DM. Here, results showed that early cognitive ToM, in particular false-belief understanding, predicts later DM independent of early verbal ability. These data support a view considering cognitive ToM as a precursor of children's DM. Copyright © 2014 Elsevier Inc. All rights reserved.

  10. Intraperitoneal chemotherapy for advanced ovarian and peritoneal cancers in patients following interval debulking surgery or primary cytoreductive surgery: Tom Baker Cancer Centre experience from 2006 to 2009.

    Science.gov (United States)

    Nelson, Gregory; Lucero, Carlos Aspe; Chu, Pamela; Nation, Jill; Ghatage, Prafull

    2010-03-01

    To describe our experience with cisplatin- and paclitaxel-based IP chemotherapy in patients treated initially with either neoadjuvant chemotherapy and interval debulking surgery (IDS) or primary cytoreductive surgery (PCRS). We performed a retrospective review of the records of 67 patients (38 IDS, 29 PCRS) enrolled in the intraperitoneal (IP) chemotherapy program at the Tom Baker Cancer Centre between 2006 and 2009. Information pertaining to patient demographics, IP chemotherapy toxicity, and catheter complications was extracted, and the median time to recurrence was calculated. Most patients in the study were aged 50 to 70 years and had a diagnosis of stage III serous ovarian cancer. Overall, 295/393 IP cycles (75%) were successfully administered. The proportion of patients completing six cycles of chemotherapy in the IDS and PCRS groups was 53% and 59%, respectively. Frequent (> 25%) Grade 1 to 2 chemotherapy toxicities included fatigue, peripheral neuropathy, and nausea. Catheter complications were observed in 34% of patients (23/67). The recurrence rates for patients completing four or more cycles of IP chemotherapy in the IDS and PCRS groups were 58% and 35%, respectively, with the median time to recurrence approximately one year. Although IP chemotherapy is well tolerated in both IDS and PCRS patients, the median time to recurrence is shorter than expected.

  11. Theory of mind impairment and its clinical correlates in patients with schizophrenia, major depressive disorder and bipolar disorder.

    Science.gov (United States)

    Wang, Yan-Yu; Wang, Yi; Zou, Ying-Min; Ni, Ke; Tian, Xue; Sun, Hong-Wei; Lui, Simon S Y; Cheung, Eric F C; Suckling, John; Chan, Raymond C K

    2017-11-06

    Although Theory of Mind (ToM) impairment has been observed in patients with a wide range of mental disorders, the similarity and uniqueness of these deficits across diagnostic groups has not been thoroughly investigated. We recruited 35 participants with schizophrenia (SCZ), 35 with bipolar disorder (BD), 35 with major depressive disorder (MDD), and 35 healthy controls in this study. All participants were matched in age, gender proportion and IQ estimates. The Yoni task, capturing both the cognitive and affective components of ToM at the first- and second-order level was administered. Repeated-measure ANOVA and MANOVA were conducted to compare the group differences in ToM performance. A network was then constructed with ToM performances, psychotic and depressive symptoms, and executive function as nodes exploring the clinical correlates of ToM. Overall, ToM impairments were observed in all patient groups compared with healthy controls, with patients with SCZ performing worse than those with BD. In second-order conditions, patients with SCZ and MDD showed deficits in both cognitive and affective conditions, while patients with BD performed significantly poorer in cognitive conditions. Network analysis showed that second-order affective ToM performance was associated with psychotic and depressive symptoms as well as executive dysfunction, while second-order affective ToM performance and negative symptoms showed relatively high centrality in the network. Patients with SCZ, MDD and BD exhibited different types and severity of impairments in ToM sub-components. Impairment in higher-order affective ToM appears to be closely related to clinical symptoms in both psychotic and affective disorders. Copyright © 2017. Published by Elsevier B.V.

  12. Worry amplifies theory-of-mind reasoning for negatively valenced social stimuli in generalized anxiety disorder.

    Science.gov (United States)

    Zainal, Nur Hani; Newman, Michelle G

    2018-02-01

    Theory-of-mind (ToM) is the ability to accurately infer others' thoughts and feelings. In generalized anxiety disorder (GAD), cognitive and emotion regulation theories allude to the plausibility that ToM is conditional on the degree of individuals' state worry, a hallmark symptom. GAD and state worry may interact to predict ToM constructs. However, no experiments have directly tested such interactional hypotheses, and used ToM as a framework to advance understanding of social cognition in GAD. This study therefore aimed to address this gap. 171 participants (69 GAD, 102 Controls) were randomly assigned to either a Worry or Relaxation induction and completed well-validated ToM decoding (Reading the Mind in the Eyes Test) and reasoning (Movie for the Assessment of Social Cognition) tasks. GAD status significantly interacted with state worry to predict accuracy of overall reasoning, cognitive-reasoning, positive-reasoning, and negative-reasoning ToM. Worry, as opposed to relaxation, led sufferers of GAD to display more accurate overall reasoning and cognitive-reasoning ToM than controls, especially for negative signals. Participants with GAD who worried, but not relaxed, were also significantly better than the norm at interpreting negative signals. These findings remained after controlling for gender, executive function, social anxiety, and depressive symptoms. For other ToM abilities, mean scores of persons with and without GAD who either worried or relaxed were normative. The ToM reasoning measure lacked self-reference, and these preliminary findings warrant replication. Theoretical implications, such as the state worry-contingent nature of ToM in GAD, and clinical implications are discussed. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. Theory of Mind and social reserve: Alternative hypothesis of progressive Theory of Mind decay during different stages of Alzheimer's disease.

    Science.gov (United States)

    Fliss, Rafika; Le Gall, Didier; Etcharry-Bouyx, Frédérique; Chauviré, Valérie; Desgranges, Béatrice; Allain, Philippe

    2016-01-01

    Although Theory of Mind (ToM) is thought to be impaired in Alzheimer's disease (AD), it remains unclear whether this impairment is linked to the level of task complexity, the heterogeneity of the studied patients, or the implication of executive dysfunctions. To elucidate this point, 42 AD patients, divided into two subgroups [moderate AD (mAD) patients (n = 19) and early AD (eAD) patients (n = 23)], and 23 matched healthy older subjects (HO) were enrolled. All participants were given (1) a false-belief task (cognitive ToM), (2) a revised version of the "Reading the Mind in the Eyes" test (affective ToM), and (3) a composite task designed to assess ToM abilities with minimal cognitive demands. Participants were also given executive tasks assessing inhibition, shifting, and updating processes. We observed a significant impairment of cognitive and composite ToM abilities in eAD patients compared with mAD patients. There was no impairment of affective ToM. Stepwise regression revealed that measures of global efficiency and executive functions (EFs) were the best predictors of progressive decay of ToM scores. These results indicate that cognitive aspects of ToM are more sensitive to AD progression than affective tasks. They also show that ToM abilities are more affected by dementia severity than by task complexity. One explanation of our results is the presence of compensatory mechanisms (social reserve) in AD.

  14. High-functioning autism patients share similar but more severe impairments in verbal theory of mind than schizophrenia patients.

    Science.gov (United States)

    Tin, L N W; Lui, S S Y; Ho, K K Y; Hung, K S Y; Wang, Y; Yeung, H K H; Wong, T Y; Lam, S M; Chan, R C K; Cheung, E F C

    2018-06-01

    Evidence suggests that autism and schizophrenia share similarities in genetic, neuropsychological and behavioural aspects. Although both disorders are associated with theory of mind (ToM) impairments, a few studies have directly compared ToM between autism patients and schizophrenia patients. This study aimed to investigate to what extent high-functioning autism patients and schizophrenia patients share and differ in ToM performance. Thirty high-functioning autism patients, 30 schizophrenia patients and 30 healthy individuals were recruited. Participants were matched in age, gender and estimated intelligence quotient. The verbal-based Faux Pas Task and the visual-based Yoni Task were utilised to examine first- and higher-order, affective and cognitive ToM. The task/item difficulty of two paradigms was examined using mixed model analyses of variance (ANOVAs). Multiple ANOVAs and mixed model ANOVAs were used to examine group differences in ToM. The Faux Pas Task was more difficult than the Yoni Task. High-functioning autism patients showed more severely impaired verbal-based ToM in the Faux Pas Task, but shared similar visual-based ToM impairments in the Yoni Task with schizophrenia patients. The findings that individuals with high-functioning autism shared similar but more severe impairments in verbal ToM than individuals with schizophrenia support the autism-schizophrenia continuum. The finding that verbal-based but not visual-based ToM was more impaired in high-functioning autism patients than schizophrenia patients could be attributable to the varied task/item difficulty between the two paradigms.

  15. Theory of mind and its relationship with executive functions and emotion recognition in borderline personality disorder.

    Science.gov (United States)

    Baez, Sandra; Marengo, Juan; Perez, Ana; Huepe, David; Font, Fernanda Giralt; Rial, Veronica; Gonzalez-Gadea, María Luz; Manes, Facundo; Ibanez, Agustin

    2015-09-01

    Impaired social cognition has been claimed to be a mechanism underlying the development and maintenance of borderline personality disorder (BPD). One important aspect of social cognition is the theory of mind (ToM), a complex skill that seems to be influenced by more basic processes, such as executive functions (EF) and emotion recognition. Previous ToM studies in BPD have yielded inconsistent results. This study assessed the performance of BPD adults on ToM, emotion recognition, and EF tasks. We also examined whether EF and emotion recognition could predict the performance on ToM tasks. We evaluated 15 adults with BPD and 15 matched healthy controls using different tasks of EF, emotion recognition, and ToM. The results showed that BPD adults exhibited deficits in the three domains, which seem to be task-dependent. Furthermore, we found that EF and emotion recognition predicted the performance on ToM. Our results suggest that tasks that involve real-life social scenarios and contextual cues are more sensitive to detect ToM and emotion recognition deficits in BPD individuals. Our findings also indicate that (a) ToM variability in BPD is partially explained by individual differences on EF and emotion recognition; and (b) ToM deficits of BPD patients are partially explained by the capacity to integrate cues from face, prosody, gesture, and social context to identify the emotions and others' beliefs. © 2014 The British Psychological Society.

  16. Improvement in cognitive and affective theory of mind with observation and imitation treatment in subjects with schizophrenia

    Directory of Open Access Journals (Sweden)

    Maria C. Pino

    2015-06-01

    Full Text Available Objective: the main objective of this study is to consider Theory of Mind (ToM, i.e. the ability to perceive other people in terms of thinking, believing and emotions, as a target for effective rehabilitative intervention, using Emotion and ToM Imitation Training (ETIT, aimed at improving social cognition and social functioning in schizophrenia. ToM impairment is a key feature of schizophrenia. According to recent literature, ToM is a multidimensional process requiring at least two components: cognitive and affective. Cognitive ToM seems to be a prerequisite for affective ToM, which requires intact empathic ability. Method: seven patients with schizophrenia completed ETIT treatment and were compared to 7 patients who participated in Problem Solving Training (PST. The participants were assessed at pre and post treatment regarding measures of cognitive (Advanced Theory of Mind Task and Social Situation Test and affective (Emotion Attribution Task and Eyes Task ToM and also empathy (Empathy Quotient. Results: our results showed that when compared to the control group, ETIT participants improved in three social cognition components evaluated (cognitive and affective ToM and empathy. Improvement in cognitive and affective ToM was found within the ETIT group pre and post treatment. Conclusions: Action observation and imitation could be important goals for future “low cost” rehabilitation treatment in several disorders in which the deficit of social cognition is considered as “core” to the disease. This represents a new perspective in the rehabilitation field.

  17. Theory of mind and hypomanic traits in general population.

    Science.gov (United States)

    Terrien, Sarah; Stefaniak, Nicolas; Blondel, Marine; Mouras, Harold; Morvan, Yannick; Besche-Richard, Chrystel

    2014-03-30

    Theory of Mind (ToM) is the ability to assign a set of mental states to yourself and others. In bipolar disorders, alteration of social relationship can be explained by the impairment of the functioning of ToM. Deficit in ToM could be a trait marker of bipolar disorder and people in the general population with high hypomanic personality scores would be more likely to develop bipolar disorders. This study examined 298 participants. Measures of hypomanic personality were evaluated using the Hypomanic Personality Scale. ToM was explored using the Yoni task. Participants also completed the BDI-II. Forward multiple regressions were performed to examine the effect of components of the HPS on the total score in the ToM task. In the women's group, no subscales of the HPS were included in the model. Conversely, the analyses performed on men revealed that the mood vitality and excitement subscale was a significant predictor of ToM abilities. Our study is the first to show the impact of certain dimensions of hypomanic personality on performance in ToM in a male sample. This result supports the idea that deficits in ToM can be a trait marker of bipolar disorder in a healthy male population. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  18. The overlapping relationship between emotion perception and theory of mind.

    Science.gov (United States)

    Mitchell, Rachel L C; Phillips, Louise H

    2015-04-01

    Socio-cognitive skills are crucial for successful interpersonal interactions. Two particularly important socio-cognitive processes are emotion perception (EP) and theory of mind (ToM), but agreement is lacking on terminology and conceptual links between these constructs. Here we seek to clarify the relationship between the two at multiple levels, from concept to neuroanatomy. EP is often regarded as a low-level perceptual process necessary to decode affective cues, while ToM is usually seen as a higher-level cognitive process involving mental state deduction. In information processing models, EP tends to precede ToM. At the neuroanatomical level, lesion study data suggest that EP and ToM are both right-hemisphere based, but there is also evidence that ToM requires temporal-cingulate networks, whereas EP requires partially separable regions linked to distinct emotions. Common regions identified in fMRI studies of EP and ToM have included medial prefrontal cortex and temporal lobe areas, but differences emerge depending on the perceptual, cognitive and emotional demands of the EP and ToM tasks. For the future, clarity of definition of EP and ToM will be paramount to produce distinct task manipulations and inform models of socio-cognitive processing. Copyright © 2015 Elsevier Ltd. All rights reserved.

  19. Links between theory of mind and executive function in young children with autism: clues to developmental primacy.

    Science.gov (United States)

    Pellicano, Elizabeth

    2007-07-01

    There has been much theoretical discussion of a functional link between theory of mind (ToM) and executive function (EF) in autism. This study sought to establish the relationship between ToM and EF in young children with autism (M = 5 years, 6 months) and to examine issues of developmental primacy. Thirty children with autism and 40 typically developing children, matched on age and ability, were assessed on a battery of tasks measuring ToM (1st- and 2nd-order false belief) and components of EF (planning, set shifting, inhibition). A significant correlation emerged between ToM and EF variables in the autism group, independent of age and ability, while ToM and higher order planning ability remained significantly related in the comparison group. Examination of the pattern of ToM-EF impairments in the autism group revealed dissociations in 1 direction only: impaired ToM with intact EF. These findings support the view that EF may be 1 important factor in the advancement of ToM understanding in autism. The theoretical implications of these findings are discussed. Copyright 2007 APA.

  20. Adding sound to theory of mind: Comparing children's development of mental-state understanding in the auditory and visual realms.

    Science.gov (United States)

    Hasni, Anita A; Adamson, Lauren B; Williamson, Rebecca A; Robins, Diana L

    2017-12-01

    Theory of mind (ToM) gradually develops during the preschool years. Measures of ToM usually target visual experience, but auditory experiences also provide valuable social information. Given differences between the visual and auditory modalities (e.g., sights persist, sounds fade) and the important role environmental input plays in social-cognitive development, we asked whether modality might influence the progression of ToM development. The current study expands Wellman and Liu's ToM scale (2004) by testing 66 preschoolers using five standard visual ToM tasks and five newly crafted auditory ToM tasks. Age and gender effects were found, with 4- and 5-year-olds demonstrating greater ToM abilities than 3-year-olds and girls passing more tasks than boys; there was no significant effect of modality. Both visual and auditory tasks formed a scalable set. These results indicate that there is considerable consistency in when children are able to use visual and auditory inputs to reason about various aspects of others' mental states. Copyright © 2017 Elsevier Inc. All rights reserved.

  1. Theory of Mind and Reading Comprehension in Deaf and Hard-of-Hearing Signing Children

    Directory of Open Access Journals (Sweden)

    Emil eHolmer

    2016-06-01

    Full Text Available Theory of Mind (ToM is related to reading comprehension in hearing children. In the present study, we investigated progression in ToM in Swedish deaf and hard-of-hearing (DHH signing children who were learning to read, as well as its assocation with reading comprehension. Thirteen children at Swedish state primary schools for DHH children performed a Swedish Sign Language (SSL version of the Wellman and Liu (2004 ToM scale, along with tests of reading comprehension, SSL comprehension, and working memory. Results indicated that ToM progression did not differ from that reported in previous studies, although ToM development was delayed despite age-appropriate sign language skills. Correlation analysis revealed that ToM was associated with reading comprehension and working memory, but not sign language comprehension. We propose that some factor not investigated in the present study, possibly represented by inference making constrained by working memory capacity, supports both ToM and reading comprehension and may thus explain the results observed in the present study.

  2. Theory of Mind and Executive Functions in Young Bilingual Children.

    Science.gov (United States)

    Dahlgren, SvenOlof; Almén, Helena; Dahlgren Sandberg, Annika

    2017-01-01

    Few studies have explored the relationship between theory of mind (ToM), executive function (EF), and bilingualism at the same time. In this study 14 young bilingual children were compared with monolingual children on a test battery composed of 5 ToM tests, 5 EF tests, and 1 test of general language ability. The result showed that despite significantly lower verbal ability, the bilingual children outperformed the monolingual ones on tests of EF. There were no differences in ToM performance. The authors argue that there is a strong relationship between bilingualism and EF, but, contrary to results from earlier studies, they could not find any relationship between bilingualism and ToM. EF did not predict ToM performance. Lack of a significant relationship could be due to the children's young age and consequently their low scores on the ToM tasks.

  3. Theory of Mind: Mechanisms, Methods, and New Directions

    Directory of Open Access Journals (Sweden)

    Lindsey Jacquelyn Byom

    2013-08-01

    Full Text Available Theory of Mind (ToM has received significant research attention. Traditional ToM research has provided important understanding of how humans reason about mental states by utilizing shared world knowledge, social cues, and the interpretation of actions, however many current behavioral paradigms are limited to static, third-person protocols. Emerging experimental approaches such as cognitive simulation and simulated social interaction offer opportunities to investigate ToM in interactive, first-person and second-person scenarios while affording greater experimental control. The advantages and limitations of traditional and emerging ToM methodologies are discussed with the intent of advancing the understanding of ToM in socially mediated situations.

  4. Fiili Hizmet Süresi Zammı Uygulamasının Türk Sosyal Güvenlik Sistemine Etkisi

    Directory of Open Access Journals (Sweden)

    Ayça ALTINDAL

    2013-11-01

    Full Text Available Türkiye’de 2008 yılında hayata geçirilen sosyal güvenlik reformu sonrası fiili hizmet süresi zammı yeniden düzenlenmiştir. Yapılan bu düzenleme ile fiili hizmet süresi zammına tabi bir işte 5510 Sayılı Kanunun 4 üncü maddesinin (a bendi kapsamında çalışan sigortalılarla (c bendi kapsamında çalışan sigortalıların malullük, yaşlılık ve ölüm sigortaları prim oranında farklılaşmaya gidilmiştir. Yapılan bu çalışma ile bahsi geçen sigortalılar arasında fiili hizmet süresi zammı hususundaki ayrışmanın etkisi incelenmiş ve bu ayrışmanın giderilmesi önerilmiştir. Ayrıca fiili hizmet süresi zammı alan sigortalıların emeklilik ödemesi ile prim tahsilatı arasında aktüeryal denge oluşturulması durumunda sosyal güvenlik sistemine yıllık 77 milyon TL ek gelir sağlanacağı tespit edilmiştir.

  5. Differential recruitment of theory of mind brain network across three tasks: An independent component analysis.

    Science.gov (United States)

    Thye, Melissa D; Ammons, Carla J; Murdaugh, Donna L; Kana, Rajesh K

    2018-07-16

    Social neuroscience research has focused on an identified network of brain regions primarily associated with processing Theory of Mind (ToM). However, ToM is a broad cognitive process, which encompasses several sub-processes, such as mental state detection and intentional attribution, and the connectivity of brain regions underlying the broader ToM network in response to paradigms assessing these sub-processes requires further characterization. Standard fMRI analyses which focus only on brain activity cannot capture information about ToM processing at a network level. An alternative method, independent component analysis (ICA), is a data-driven technique used to isolate intrinsic connectivity networks, and this approach provides insight into network-level regional recruitment. In this fMRI study, three complementary, but distinct ToM tasks assessing mental state detection (e.g. RMIE: Reading the Mind in the Eyes; RMIV: Reading the Mind in the Voice) and intentional attribution (Causality task) were each analyzed using ICA in order to separately characterize the recruitment and functional connectivity of core nodes in the ToM network in response to the sub-processes of ToM. Based on visual comparison of the derived networks for each task, the spatiotemporal network patterns were similar between the RMIE and RMIV tasks, which elicited mentalizing about the mental states of others, and these networks differed from the network derived for the Causality task, which elicited mentalizing about goal-directed actions. The medial prefrontal cortex, precuneus, and right inferior frontal gyrus were seen in the components with the highest correlation with the task condition for each of the tasks highlighting the role of these regions in general ToM processing. Using a data-driven approach, the current study captured the differences in task-related brain response to ToM in three distinct ToM paradigms. The findings of this study further elucidate the neural mechanisms associated

  6. Temporal bone CT findings of tuberculous otitis media : comparison with chronic otitis media

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    Chang, Jeong A; Rho, Myung Ho; Kim, Young Min; Lee, Ho Seung; Choi, Pil Yeob; Seong, Young Soon; Kwon, Jae Soo; Lee, Sang Wook [Masan Samsung Hospital, Sungkyunkwan Univ. College of Medicine, Seoul (Korea, Republic of); Jung, Keon Sik [Pohang Sunrin Hospital, Pohang (Korea, Republic of)

    1999-06-01

    To compare the differential findings of tuberculous otitis media(TOM) with those of chronic sup purative otitis media with or without cholesteatoma, as seen on high resolution temporal bone CT. We retrospectively reviewed 14 cases of TOM, 30 cases of chronic suppurative otitis media(CSOM), and 30 cases of chronic otitis media with cholesteatoma(Chole). All had been pathologically confirmed. We evaluated the preservation of mastoid cells without sclerotic change, the location and extension of soft tissue to the external auditary canal, and erosion of ossicles, the tegmen tympani, scutum, bony labyrinth, facial nerve canal and sigmoid sinus, and the presence of intracranial complications. Soft tissue in the mastoid antrum was seen in all cases of TOM(100%), 29 cases of CSOM(96.7%), and 26 cases of Chole(86.7%). In contrast, the soft tissue in the entire middle ear cavity was noted in 13 cases of TOM(92.8%), 7 cases of CSOM(23.3%), and 12 cases of Chole(40%). Soft tissue extended to the superior aspect of the external auditory canal in 4 cases of TOM (28.6%) and 5 cases of Chole (16.7%). Mastoid air cells were seen in 9 cases of TOM (64.3%), 4 cases of CSOM (13.3%), and 3 cases of Chole(10%). Ossicular erosion was noted in 6 cases of TOM (42.9%), 12 cases of CSOM (40%), and 26 cases of Chole(86.7%), while in one case of TOM (7.1%), 5 cases of CSOM (16.7%), and 15 cases of Chole(50%) there was erosion of the scutum. In one case of TOM, follow-up CT study after 9 months of antituberculous medication without surgery revealed complete clearing of previously noted soft tissue in the middle ear cavity. Specific CT findings of TOM were not seen, but if there were findings of soft tissue in the entire middle ear cavity, soft tissue extension to the external auditory canal, preservation of mastoid air cells without sclerotic change, and intact scutum, TOM may be differentiated from other chronic otitis media.

  7. Using fiction to assess mental state understanding: a new task for assessing theory of mind in adults.

    Directory of Open Access Journals (Sweden)

    David Dodell-Feder

    Full Text Available Social functioning depends on the ability to attribute and reason about the mental states of others--an ability known as theory of mind (ToM. Research in this field is limited by the use of tasks in which ceiling effects are ubiquitous, rendering them insensitive to individual differences in ToM ability and instances of subtle ToM impairment. Here, we present data from a new ToM task--the Short Story Task (SST--intended to improve upon many aspects of existing ToM measures. More specifically, the SST was designed to: (a assess the full range of individual differences in ToM ability without suffering from ceiling effects; (b incorporate a range of mental states of differing complexity, including epistemic states, affective states, and intentions to be inferred from a first- and second-order level; (c use ToM stimuli representative of real-world social interactions; (d require participants to utilize social context when making mental state inferences; (e exhibit adequate psychometric properties; and (f be quick and easy to administer and score. In the task, participants read a short story and were asked questions that assessed explicit mental state reasoning, spontaneous mental state inference, and comprehension of the non-mental aspects of the story. Responses were scored according to a rubric that assigned greater points for accurate mental state attributions that included multiple characters' mental states. Results demonstrate that the SST is sensitive to variation in ToM ability, can be accurately scored by multiple raters, and exhibits concurrent validity with other social cognitive tasks. The results support the effectiveness of this new measure of ToM in the study of social cognition. The findings are also consistent with studies demonstrating significant relationships among narrative transportation, ToM, and the reading of fiction. Together, the data indicate that reading fiction may be an avenue for improving ToM ability.

  8. Temporal bone CT findings of tuberculous otitis media : comparison with chronic otitis media

    International Nuclear Information System (INIS)

    Chang, Jeong A; Rho, Myung Ho; Kim, Young Min; Lee, Ho Seung; Choi, Pil Yeob; Seong, Young Soon; Kwon, Jae Soo; Lee, Sang Wook; Jung, Keon Sik

    1999-01-01

    To compare the differential findings of tuberculous otitis media(TOM) with those of chronic sup purative otitis media with or without cholesteatoma, as seen on high resolution temporal bone CT. We retrospectively reviewed 14 cases of TOM, 30 cases of chronic suppurative otitis media(CSOM), and 30 cases of chronic otitis media with cholesteatoma(Chole). All had been pathologically confirmed. We evaluated the preservation of mastoid cells without sclerotic change, the location and extension of soft tissue to the external auditary canal, and erosion of ossicles, the tegmen tympani, scutum, bony labyrinth, facial nerve canal and sigmoid sinus, and the presence of intracranial complications. Soft tissue in the mastoid antrum was seen in all cases of TOM(100%), 29 cases of CSOM(96.7%), and 26 cases of Chole(86.7%). In contrast, the soft tissue in the entire middle ear cavity was noted in 13 cases of TOM(92.8%), 7 cases of CSOM(23.3%), and 12 cases of Chole(40%). Soft tissue extended to the superior aspect of the external auditory canal in 4 cases of TOM (28.6%) and 5 cases of Chole (16.7%). Mastoid air cells were seen in 9 cases of TOM (64.3%), 4 cases of CSOM (13.3%), and 3 cases of Chole(10%). Ossicular erosion was noted in 6 cases of TOM (42.9%), 12 cases of CSOM (40%), and 26 cases of Chole(86.7%), while in one case of TOM (7.1%), 5 cases of CSOM (16.7%), and 15 cases of Chole(50%) there was erosion of the scutum. In one case of TOM, follow-up CT study after 9 months of antituberculous medication without surgery revealed complete clearing of previously noted soft tissue in the middle ear cavity. Specific CT findings of TOM were not seen, but if there were findings of soft tissue in the entire middle ear cavity, soft tissue extension to the external auditory canal, preservation of mastoid air cells without sclerotic change, and intact scutum, TOM may be differentiated from other chronic otitis media

  9. Using Fiction to Assess Mental State Understanding: A New Task for Assessing Theory of Mind in Adults

    Science.gov (United States)

    Dodell-Feder, David; Lincoln, Sarah Hope; Coulson, Joseph P.; Hooker, Christine I.

    2013-01-01

    Social functioning depends on the ability to attribute and reason about the mental states of others – an ability known as theory of mind (ToM). Research in this field is limited by the use of tasks in which ceiling effects are ubiquitous, rendering them insensitive to individual differences in ToM ability and instances of subtle ToM impairment. Here, we present data from a new ToM task – the Short Story Task (SST) - intended to improve upon many aspects of existing ToM measures. More specifically, the SST was designed to: (a) assess the full range of individual differences in ToM ability without suffering from ceiling effects; (b) incorporate a range of mental states of differing complexity, including epistemic states, affective states, and intentions to be inferred from a first- and second-order level; (c) use ToM stimuli representative of real-world social interactions; (d) require participants to utilize social context when making mental state inferences; (e) exhibit adequate psychometric properties; and (f) be quick and easy to administer and score. In the task, participants read a short story and were asked questions that assessed explicit mental state reasoning, spontaneous mental state inference, and comprehension of the non-mental aspects of the story. Responses were scored according to a rubric that assigned greater points for accurate mental state attributions that included multiple characters’ mental states. Results demonstrate that the SST is sensitive to variation in ToM ability, can be accurately scored by multiple raters, and exhibits concurrent validity with other social cognitive tasks. The results support the effectiveness of this new measure of ToM in the study of social cognition. The findings are also consistent with studies demonstrating significant relationships among narrative transportation, ToM, and the reading of fiction. Together, the data indicate that reading fiction may be an avenue for improving ToM ability. PMID:24244736

  10. Theory of Mind and attachment styles in people with psychotic disorders, their siblings, and controls.

    Science.gov (United States)

    Pos, Karin; Bartels-Velthuis, Agna A; Simons, Claudia J P; Korver-Nieberg, Nikie; Meijer, Carin J; de Haan, Lieuwe

    2015-02-01

    Impaired Theory of Mind (ToM) and insecure (adult) attachment styles have been found in persons with schizophrenia as well as in their healthy siblings. ToM refers to the ability to infer mental states of self and others including beliefs and emotions. Insecure attachment is proposed to underlie impaired ToM, and comprises avoidant (discomfort with close relationships, high value of autonomy) and anxious (separation anxiety, dependency on others) attachment. Insight into the association between attachment style and ToM is clinically relevant, as it enhances our understanding and clinical approach to social dysfunction in schizophrenia. Therefore, we studied the association between insecure attachment styles and ToM in patients with schizophrenia, their siblings, and healthy controls. A total of 111 patients with a diagnosis in the schizophrenia spectrum, 106 non-affected siblings and 63 controls completed the Psychosis Attachment Measure, the Conflicting Beliefs and Emotions, a subsection of the Wechsler Adult Intelligence Scale, and the Childhood Trauma Questionnaire-Short Form. Severity of symptoms was assessed with the Community Assessment of Psychic Experiences and the Positive and Negative Syndrome Scale. After controlling for sex, intelligence, history of trauma and symptom severity, avoidant attachment was significantly associated with cognitive as well as with affective ToM, showing U-shaped associations, indicating better ToM performance for patients with lower or higher levels of avoidant attachment compared to medium levels. Anxious attachment in patients was associated with more problems in cognitive ToM. The results from this study support the idea that an anxious attachment style is associated with worse ToM performance in patients. Results also suggested a potential protective role of higher levels of avoidant attachment on ToM. These findings bear clinical relevance, as activation of (insecure) attachment mechanisms may affect interpersonal

  11. Using memories to understand others: the role of episodic memory in theory of mind impairment in Alzheimer disease.

    Science.gov (United States)

    Moreau, Noémie; Viallet, François; Champagne-Lavau, Maud

    2013-09-01

    Theory of mind (TOM) refers to the ability to infer one's own and other's mental states. Growing evidence highlighted the presence of impairment on the most complex TOM tasks in Alzheimer disease (AD). However, how TOM deficit is related to other cognitive dysfunctions and more specifically to episodic memory impairment - the prominent feature of this disease - is still under debate. Recent neuroanatomical findings have shown that remembering past events and inferring others' states of mind share the same cerebral network suggesting the two abilities share a common process .This paper proposes to review emergent evidence of TOM impairment in AD patients and to discuss the evidence of a relationship between TOM and episodic memory. We will discuss about AD patients' deficit in TOM being possibly related to their difficulties in recollecting memories of past social interactions. Copyright © 2013 Elsevier B.V. All rights reserved.

  12. Understanding minds: early cochlear implantation and the development of theory of mind in children with profound hearing impairment.

    Science.gov (United States)

    Sundqvist, Annette; Lyxell, Björn; Jönsson, Radoslava; Heimann, Mikael

    2014-03-01

    The present study investigates how auditory stimulation from cochlear implants (CI) is associated with the development of Theory of Mind (ToM) in severely and profoundly hearing impaired children with hearing parents. Previous research has shown that deaf children of hearing parents have a delayed ToM development. This is, however, not always the case with deaf children of deaf parents, who presumably are immersed in a more vivid signing environment. Sixteen children with CI (4.25 to 9.5 years of age) were tested on measures of cognitive and emotional ToM, language and cognition. Eight of the children received their first implant relatively early (before 27 months) and half of them late (after 27 months). The two groups did not differ in age, gender, language or cognition at entry of the study. ToM tests included the unexpected location task and a newly developed Swedish social-emotional ToM test. The tests aimed to test both cognitive and emotional ToM. A comparison group of typically developing hearing age matched children was also added (n=18). Compared to the comparison group, the early CI-group did not differ in emotional ToM. The late CI-group differed significantly from the comparison group on both the cognitive and emotional ToM tests. The results revealed that children with early cochlear implants solved ToM problems to a significantly higher degree than children with late implants, although the groups did not differ on language or cognitive measures at baseline. The outcome suggests that early cochlear implantation for deaf children in hearing families, in conjunction with early social and communicative stimulation in a language that is native to the parents, can provide a foundation for a more normalized ToM development. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  13. Martinho Lutero (1483-1546 e Tomás Müntzer (1489-1525: a justificação teológica da autoridade secular e da revolução política

    Directory of Open Access Journals (Sweden)

    Dreher, Martin Norberto

    2006-01-01

    Full Text Available A Reforma em território alemão possui duas figuras, por vezes próximas entre si, por vezes muito distantes: Lutero e Tomás Müntzer. À medida que foi se envolvendo na vida de seus fiéis, Müntzer foi tomando caminhos próprios, discordando de Lutero que este tomava a "Palavra, em sua realidade objetiva, como constitutiva da Igreja, e afirmando que os verdadeiros fiéis são os que possuem a experiência subjetiva do "Espírito". Também contra Lutero, que defende a resistência à autoridade, mas em questões seculares aceita a tirania, Müntzer, que vê a fé fortemente inserida no social, defende a revolução armada contra os príncipes. Müntzer não nega a graça, mas esta possui papel secundário em seu pensamento, enquanto, para Lutero, ela se coloca no centro de suas preocupações teológicas

  14. Reading literary fiction improves theory of mind.

    Science.gov (United States)

    Kidd, David Comer; Castano, Emanuele

    2013-10-18

    Understanding others' mental states is a crucial skill that enables the complex social relationships that characterize human societies. Yet little research has investigated what fosters this skill, which is known as Theory of Mind (ToM), in adults. We present five experiments showing that reading literary fiction led to better performance on tests of affective ToM (experiments 1 to 5) and cognitive ToM (experiments 4 and 5) compared with reading nonfiction (experiments 1), popular fiction (experiments 2 to 5), or nothing at all (experiments 2 and 5). Specifically, these results show that reading literary fiction temporarily enhances ToM. More broadly, they suggest that ToM may be influenced by engagement with works of art.

  15. Neurobiological correlates of theory of mind in psychosis proneness

    NARCIS (Netherlands)

    Modinos, Gemma; Renken, Remco; Shamay-Tsoory, Simone G.; Ormel, Johan; Aleman, Andre

    2010-01-01

    Theory of mind (TOM) refers to the capacity to infer one's own and other persons' mental states. ToM abilities are compromised in schizophrenia, in association with dysfunctional activity in predominantly prefrontal brain regions. Prior behavioral studies have also suggested ToM deficits in healthy

  16. Deficits of cognitive theory of mind and its relationship with functioning in individuals with an at-risk mental state and first-episode psychosis.

    Science.gov (United States)

    Ohmuro, Noriyuki; Katsura, Masahiro; Obara, Chika; Kikuchi, Tatsuo; Sakuma, Atsushi; Iizuka, Kunio; Hamaie, Yumiko; Ito, Fumiaki; Matsuoka, Hiroo; Matsumoto, Kazunori

    2016-09-30

    Disturbance of theory of mind (ToM) and its relationship with functioning in schizophrenia is well documented; however, this is unclear in spectrum disorders like at-risk mental state (ARMS) and first-episode psychosis (FEP). To assess mental state reasoning ability, the total score of the Theory of Mind Picture Stories Task questionnaire was compared among 36 Japanese individuals with ARMS, 40 with FEP, and 25 healthy controls (HC). Pearson's correlations between ToM performance and global and social functioning indices were examined. ToM performance for FEP and ARMS subjects was significantly lower than that for HC, though the significance of the difference between the ARMS and HC disappeared when controlling for premorbid IQ. ToM deficits in ARMS subjects were confirmed only in the comprehension of higher-order false belief. Only among FEP subjects were ToM performance and global functioning significantly correlated, though the significance disappeared when controlling for neurocognitive performance or dose of antipsychotics. No significant correlation between ToM performance and social functioning was observed in the FEP and ARMS groups. The current findings suggest that ToM deficits emerge in ARMS subjects confined within a higher-order domain, and that the relationship between ToM impairment and functional deterioration might be established after psychosis onset. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  17. Person perception precedes theory of mind: an event related potential analysis.

    Science.gov (United States)

    Wang, Y W; Lin, C D; Yuan, B; Huang, L; Zhang, W X; Shen, D L

    2010-09-29

    Prior to developing an understanding of another person's mental state, an ability termed "theory of mind" (ToM), a perception of that person's appearance and actions is required. However the relationship between this "person perception" and ToM is unclear. To investigate the time course of ToM and person perception, event-related potentials (ERP) were recorded while 17 normal adults received three kinds of visual stimuli: cartoons involving people (person perception cartoons), cartoons involving people and also requiring ToM for comprehension (ToM cartoons), and scene cartoons. We hypothesized that the respective patterns of brain activation would be different under these three stimuli, at different stages in time. Our findings supported this proposal: the peak amplitudes of P200 for scene cartoons were significantly lower than for person perception or ToM cartoons, while there were no significant differences between the latter two for P200. During the 1000-1300 ms epoch, the mean amplitudes of the late positive components (LPC) for person perception were more positive than for scene representation, while the mean amplitudes of the LPC for ToM were more positive than for person perception. The present study provides preliminary evidence of the neural dynamic that underlies the dissociation between person perception and ToM. Copyright 2010 IBRO. Published by Elsevier Ltd. All rights reserved.

  18. Obituary: Thomas Robert Metcalf, 1961-2007

    Science.gov (United States)

    Leka, K. D.

    2007-12-01

    The astronomy community lost a good friend when Tom Metcalf was killed in a skiing accident on Saturday, 7 July 2007, in the mountains near Boulder, Colorado. Tom was widely known for prolific work on solar magnetic fields, hard-X-ray imaging of solar flares, and spectral line diagnostics. He was often characterized as "one of the nicest guys in science." Born October 5, 1961 in Cheverly, Maryland, to Fred and Marilyn, Thomas R. Metcalf joined his sister, Karen, two years his elder, in a close family that loved sailing, inquisitiveness, and the natural world. Sibling rivalry (usually a Tonka truck intruding on Barbie's sub-table "castle") melted when Tom and Karen collaborated on elaborately engineered room-sized blanket-forts. Tom confidently signed up at age of three to crew for his family's sailboat; when the family moved to California in 1966, as Tom's father took a Professor of Mathematics position at the University of California Riverside, Tom's love for sailing was well-established. Week-long cruises or short trips in the harbor were all fun; when school friends came aboard, it was even better--if "only slightly too crowded" from the adults' points of view. Tom's introduction to astronomy began one cold, very clear, December night in the early 1970s, on a family camping trip to Death Valley. The "Sidewalk Astronomers of San Francisco" had lined the sidewalk near the visitors' center with all sorts of telescopes for public viewing. Soon after, Tom and his boyhood friend Jim O'Linger were building their own scopes, attending "Amateur Telescope Makers" conferences, and Tom was setting up his scope on a sidewalk for public viewing. In 1986, Tom set up his telescope on the bluffs above Dana Point Harbor, and gave numerous strangers a stunning view of Halley's Comet. His interest in physics and mathematics became evident during Tom's last years in high school (Poly High in Riverside), and as a senior he qualified to take freshman Physics at the University of

  19. Deaf and hearing children's development of theory of mind, peer popularity, and leadership during middle childhood.

    Science.gov (United States)

    Peterson, Candida C; O'Reilly, Karin; Wellman, Henry M

    2016-09-01

    This study had two primary aims. First, we compared deaf and hearing children during middle and late childhood on (a) cognitive understanding of basic and advanced theory of mind (ToM) and (b) social dimensions of peer group relations, including popularity, isolation, leadership, and the disposition to interact positively with peers. Second, using correlational analyses, we examined ToM's connections with these social variables to see whether and how ToM impacts children's social lives. A total of 57 children (36 deaf children of hearing parents and 21 hearing children) 6 to 14years of age completed a 6-step developmental ToM Scale, and their teachers reported on the social variables. Hearing children outperformed deaf children on ToM and all teacher-rated variables. For deaf children, popularity correlated positively, and social isolation correlated negatively, with ToM even after controlling for age, gender, and language ability. For hearing children, the only ToM link was a weak correlation with leadership. Possible reasons for the differences between deaf and hearing groups are discussed, together with the likelihood of bidirectional causal links and implications for deaf children's social development in school. Copyright © 2015 Elsevier Inc. All rights reserved.

  20. Multiple roles for executive control in belief-desire reasoning: distinct neural networks are recruited for self perspective inhibition and complexity of reasoning.

    Science.gov (United States)

    Hartwright, Charlotte E; Apperly, Ian A; Hansen, Peter C

    2012-07-16

    Belief-desire reasoning is a core component of 'Theory of Mind' (ToM), which can be used to explain and predict the behaviour of agents. Neuroimaging studies reliably identify a network of brain regions comprising a 'standard' network for ToM, including temporoparietal junction and medial prefrontal cortex. Whilst considerable experimental evidence suggests that executive control (EC) may support a functioning ToM, co-ordination of neural systems for ToM and EC is poorly understood. We report here use of a novel task in which psychologically relevant ToM parameters (true versus false belief; approach versus avoidance desire) were manipulated orthogonally. The valence of these parameters not only modulated brain activity in the 'standard' ToM network but also in EC regions. Varying the valence of both beliefs and desires recruits anterior cingulate cortex, suggesting a shared inhibitory component associated with negatively valenced mental state concepts. Varying the valence of beliefs additionally draws on ventrolateral prefrontal cortex, reflecting the need to inhibit self perspective. These data provide the first evidence that separate functional and neural systems for EC may be recruited in the service of different aspects of ToM. Copyright © 2012 Elsevier Inc. All rights reserved.

  1. Relations between theory of mind and executive function in middle childhood: A short-term longitudinal study.

    Science.gov (United States)

    Lecce, Serena; Bianco, Federica; Devine, Rory T; Hughes, Claire

    2017-11-01

    Studies with preschool children have shown significant links between children's executive function (EF) and theory of mind (ToM), but few studies have examined these associations in primary school children. To address this gap, we designed a three-wave cross-lagged longitudinal study in which we followed a group of 113 children (61 boys) across three time points from age 9.5-10.5years (mean age at Time 1=112.3months, SD=4.18; mean age at Time 2=118.3months, SD=4.15; mean age at Time 3=124.7months, SD=4.06). At each time point, we measured EF (working memory and inhibitory control), ToM, and language. Our analyses showed (a) moderate rank-order stability of individual differences in both EF and ToM and (b) growth in ToM task performance across time. Cross-lagged longitudinal analyses revealed an asymmetric developmental relation between ToM and working memory. Early working memory predicted later ToM but not vice versa. Our results suggest a specific role for working memory in the ongoing development of ToM in middle childhood. Copyright © 2017 Elsevier Inc. All rights reserved.

  2. Hyper-Theory-of-Mind in Children with Psychotic Experiences

    OpenAIRE

    Clemmensen, Lars; van Os, Jim; Skovgaard, Anne Mette; Vaever, Mette; Blijd-Hoogewys, Els M. A.; Bartels-Velthuis, Agna A.; Jeppesen, Pia

    2014-01-01

    Background: Alterations in Theory-of-Mind (ToM) are associated with psychotic disorder. In addition, studies in children have documented that alterations in ToM are associated with Psychotic Experiences (PE). Our aim was to examine associations between an exaggerated type of ToM (HyperToM) and PE in children. Children with this type of alteration in ToM infer mental states when none are obviously suggested, and predict behaviour on the basis of these erroneous beliefs. Individuals with HyperT...

  3. Ken Jacobs and the Perverted Archival Image

    OpenAIRE

    Gonçalo Pablo

    2016-01-01

    This paper analyses two recent works by American filmmaker Ken Jacobs that deal with aspects of remediation. The first is A Tom Tom Chaser, in which Jacobs records the telecine process that transforms the classic silent film Tom, Tom, the Piper’s Son from chemical into electronic media. The film is riddled with poetic turns inviting the audience to rediscover the medial noise hidden by images. Moreover, Jacobs focuses on the moment of transition from a material medium (the film strip) to the ...

  4. Getting Specific

    DEFF Research Database (Denmark)

    Ayres, Phil

    2005-01-01

    The Art and Architecture Partnership, known for commissioning public works such as Softroom's Belvedere and James Turrell's Skyspace, has recently awarded its first architectural residency at Kielder to sixteen*(makers). Here, Phil Ayres introduces initial questions for an evolutionary design...

  5. Environmental Impact Statement/Environmental Impact Report for the Proposed Marathon Industrial/Commercial Business Center Tract 5167, Hayward California. Supplement.

    Science.gov (United States)

    1987-06-01

    National Technical Information Services, U.S. Department of Commerce, Springfield, VA. (1982). Ayres, Judith E., Regional Administrator, EPA, written...Sernmnts (AOA) regarding: a. Wether project emissions have been considered in formulating the Seattaiment Area Plan (MP),. and awe consistent with emission

  6. Theory of mind, insecure attachment and paranoia in adolescents with early psychosis and healthy controls

    NARCIS (Netherlands)

    Korver-Nieberg, Nikie; Fett, Anne-Kathrin J.; Meijer, Carin J.; Koeter, Maarten W. J.; Shergill, Sukhi S.; de Haan, Lieuwe; Krabbendam, Lydia

    2013-01-01

    Impaired Theory of Mind (ToM) is found in adults with schizophrenia and is associated with paranoid symptoms. Insecure attachment is proposed to underlie impaired ToM as well as paranoia. Insight into associations between insecure attachment and impaired ToM skills may help clinicians and patients

  7. Relationship between insight and theory of mind in schizophrenia: A meta-analysis.

    Science.gov (United States)

    Bora, Emre

    2017-12-01

    Poor insight in schizophrenia has been associated with executive dysfunction and deficits in general cognitive ability. The overall outcome of available neurocognitive studies suggests that there is a significant but modest relationship between cognitive deficits and poor insight in schizophrenia. However, social cognitive abilities, particularly, theory of mind (ToM), might also play a role in poor insight in schizophrenia. A novel meta-analysis of the relationship between ToM and insight in schizophrenia was conducted. Current meta-analysis included 16 studies including 1085 patients with schizophrenia-spectrum disorders. There was a significant association between ToM and clinical insight (r=0.28, CI=0.20-0.36). By contrast, there was no significant relationship between ToM and cognitive insight. Current findings suggest that there is a small but significant relationship between ToM and clinical insight in schizophrenia. ToM impairment is one of the factors contributing to poor insight in schizophrenia. Copyright © 2017 Elsevier B.V. All rights reserved.

  8. Simple Mindreading Abilities Predict Complex Theory of Mind: Developmental Delay in Autism Spectrum Disorders.

    Science.gov (United States)

    Pino, Maria Chiara; Mazza, Monica; Mariano, Melania; Peretti, Sara; Dimitriou, Dagmara; Masedu, Francesco; Valenti, Marco; Franco, Fabia

    2017-09-01

    Theory of mind (ToM) is impaired in individuals with autism spectrum disorders (ASD). The aims of this study were to: (i) examine the developmental trajectories of ToM abilities in two different mentalizing tasks in children with ASD compared to TD children; and (ii) to assess if a ToM simple test known as eyes-test could predict performance on the more advanced ToM task, i.e. comic strip test. Based on a sample of 37 children with ASD and 55 TD children, our results revealed slower development at varying rates in all ToM measures in children with ASD, with delayed onset compared to TD children. These results could stimulate new treatments for social abilities, which would lessen the social deficit in ASD.

  9. Translating child development research into practice: Can teachers foster children's theory of mind in primary school?

    Science.gov (United States)

    Bianco, Federica; Lecce, Serena

    2016-12-01

    Translating research findings into practice should be one of the objectives of developmental psychology. Recently, research demonstrated the existence of individual differences in theory of mind (ToM) during middle childhood that are crucial for children's academic and social adjustment. This study aims to transfer the results of recent experimental studies on ToM interventions into primary-school teachers' practices. It examines whether a ToM training programme, based on conversations about mental states, can be effective under real-world school conditions and if it can be translated in such a way that it becomes suitable for primary-school teachers. Seventy-two 8- to 9-year-old children took part in the study. A total of four classes were recruited and randomly assigned to the experimental (34 children, 18 boys) or to the control condition (38 children, 18 boys). The ToM group and the control group were matched at pre-test for age, ToM, socio-economic background, verbal ability, working memory, and planning. Teachers were trained in four teacher-training sessions; the classroom-training programme was delivered by teachers in four sessions (each 50 min long). Children were assessed before the intervention, after the end of the programme, and 2 months later. The ToM group improved ToM skills significantly more than the control group both in the short and in the long term. Teachers can successfully promote their pupils' ToM development during their regular teaching hours. Results are discussed in the light of the importance of ToM promotion for children's school adjustment. © 2016 The British Psychological Society.

  10. Hyper-Theory-of-Mind in Children with Psychotic Experiences

    NARCIS (Netherlands)

    Clemmensen, Lars; van Os, Jim; Skovgaard, Anne Mette; Vaever, Mette; Blijd-Hoogewys, Els M. A.; Bartels-Velthuis, Agna A.; Jeppesen, Pia

    2014-01-01

    Background: Alterations in Theory-of-Mind (ToM) are associated with psychotic disorder. In addition, studies in children have documented that alterations in ToM are associated with Psychotic Experiences (PE). Our aim was to examine associations between an exaggerated type of ToM (HyperToM) and PE in

  11. Rethinking Theory of Mind in High-Functioning Autism Spectrum Disorder

    Science.gov (United States)

    Scheeren, Anke M.; de Rosnay, Marc; Koot, Hans M.; Begeer, Sander

    2013-01-01

    Background: The sociocommunicative problems in autism spectrum disorder (ASD) are traditionally linked to impairments in Theory of Mind (ToM), the ability to ascribe mental states to others. Although ToM impairments are consistently reported in young children with ASD, findings on more advanced ToM understanding in older individuals with…

  12. Effects and Moderators of a Short Theory of Mind Intervention for Children with Autism Spectrum Disorder: A Randomized Controlled Trial

    NARCIS (Netherlands)

    Begeer, Sander; Howlin, Patricia; Hoddenbach, Elske; Clauser, Cassandra; Lindauer, Ramon; Clifford, Pamela; Gevers, Carolien; Boer, Frits; Koot, Hans M.

    2015-01-01

    Limited perspective taking or "Theory of Mind" (ToM) abilities are a core deficit of autism, and many interventions are aimed to improve ToM abilities. In this study, we investigated the effectiveness of a ToM treatment for children with autism spectrum disorders (ASD) and, for the first time, the

  13. Meta-analysis of theory of mind in anorexia nervosa and bulimia nervosa: A specific İmpairment of cognitive perspective taking in anorexia nervosa?

    Science.gov (United States)

    Bora, Emre; Köse, Sezen

    2016-08-01

    Deficits in theory of mind (ToM), ability to infer mental states of others, can play a significant role in interpersonal difficulties and/or unawareness of illness observed in AN and other eating disorders including bulimia Nervosa (BN). Current meta-analysis aimed to summarize available evidence for deficits in ToM in AN and BN and examine the effects of number of study-level variables on observed findings. In this meta-analysis, 15 studies (22 samples with eating disorders) investigating ToM performances of 677 individuals with AN or BN and 514 healthy controls were included. AN was associated with significant deficits in ToM (d = 0.59) which were more pronounced in the acute patients (d = 0.67). Small sized deficits in ToM were observed in BN (d = 0.34) and recovered AN (d = 0.35). Both cognitive perspective-taking (ToM-PT) (d = 0.99) and decoding mental states (ToM-decoding) (d = 0.61) aspects of ToM were impaired in acute AN. ToM-decoding impairment in BN was modest. There was no evidence for significant ToM-PT deficit in BN. Several study-level variables including longer duration of illness, lower BMI, and depressive symptoms were associated with more severe deficits in ToM in AN. ToM deficits, particularly in ToM-PT, can be a specific feature of AN but not BN. ToM impairment can contribute to poor insight, treatment resistance, and social impairment in AN. © 2016 Wiley Periodicals, Inc. RESUMEN META ANÁLISIS DE LA TEORÍA DE LA MENTE EN ANOREXIA NERVOSA Y BULIMIA NERVOSA: ¿Un deterioro de la toma de perspectiva cognitiva en Anorexia Nervosa? Las deficiencias en la teoría de la mente (ToM), la habilidad parar inferir los estados mentales de otros, pueden jugar una función significativa en las dificultades interpersonales y/o falta de reconocimiento de la enfermedad observada en Anorexia Nervosa (AN) y otros trastornos de la conducta alimentaria incluyendo la Bulimia Nervosa (BN). Los meta análisis actuales dirigidos a resumir la

  14. Psikolojik Sermaye ve Çalışanlar Üzerinde Etkisi: Banka Sektöründe Bir Alan Çalışması

    OpenAIRE

    YEŞİL, Salih; YETİŞ, Emirhan; TELLİ, Sümeyra

    2016-01-01

    Bu çalışmanın amacı psikolojik sermayenin çalışanlar üzerinde etkilerini (bilgi paylaşımı, iş tatmini, işten ayrılma eğilimi ve yenilikçi davranış) belirlemeye yöneliktir. Araştırmanın alan çalışması, bir banka çalışanları üzerinde yapılmış, analiz edilmiş ve yorumlanmıştır. Araştırma sonucunda psikolojik sermayenin çalışanlar açısından bilgi paylaşımı, iş tatmini, işten ayrılma niyeti, performans ve yenilikçi davranış üzerinde farklı düzeylerde etkileri olduğu belirlenmiştir. Bu sonuç psiko...

  15. Affective and cognitive theory of mind in borderline personality disorder: The role of comorbid depression.

    Science.gov (United States)

    Zabihzadeh, Abbas; Maleki, Gheysar; Richman, Mara J; Hatami, AmirJalal; Alimardani, Zahedeh; Heidari, Mostafa

    2017-11-01

    Disturbed interpersonal relationships and misreading of others' intentions are core symptoms of borderline personality disorder (BPD). Despite these impairments, some studies have found an enhanced theory of mind (ToM) in BPD patients. Taking this into consideration, the current study attempts to further understand these discrepancies by separating ToM into two domains: affective and cognitive. Moreover, the study considered the role of comorbid symptoms of depression in these patients. Subjects were 21 patients with BPD, 23 patients with BPD and comorbid major depressive disorder (MDD), and 25 healthy controls (HC). ToM was measured with the Reading the Mind in the Eyes Test (RMET) and the Faux Pas Task, which assessed the affective and cognitive aspects of ToM, respectively. In addition, all participants were evaluated with the Beck Depression Inventory (BDI). Results showed that in both BPD groups (i.e., BPD without MDD and BPD with MDD) affective ToM scores were higher than in the HC group; however, in the cognitive ToM, the HC group performed better than the both BPD groups. Also, overall the BPD group with MDD had decreased ToM skills. Finally, BPD groups received greater scores on the BDI as compared to the HC group. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. Developmental trends of hot and cool executive function in school-aged children with and without autism spectrum disorder: Links with theory of mind.

    Science.gov (United States)

    Kouklari, Evangelia-Chrysanthi; Tsermentseli, Stella; Monks, Claire P

    2018-03-26

    The development of executive function (EF) in autism spectrum disorder (ASD) has been investigated using only "cool"-cognitive EF tasks while there is limited knowledge regarding the development of "hot"-affective EF. Although cool EF development and its links to theory of mind (ToM) have been widely examined, understanding of the influence of hot EF to ToM mechanisms is minimal. The present study introduced a longitudinal design to examine the developmental changes in cool and hot EF of children with ASD (n = 45) and matched (to age and IQ) controls (n = 37) as well as the impact of EF on ToM development over a school year. For children with ASD, although selective cool (working memory and inhibition) and hot (affective decision making) EF domains presented age-related improvements, they never reached the performance level of the control group. Early cool working memory predicted later ToM in both groups but early hot delay discounting predicted later ToM only in the ASD group. No evidence was found for the reverse pattern (early ToM predicting later EF). These findings suggest that improvements in some EF aspects are evident in school age in ASD and highlight the crucial role that both cool and hot EF play in ToM development.

  17. Aberrant functioning of the theory-of-mind network in children and adolescents with autism.

    Science.gov (United States)

    Kana, Rajesh K; Maximo, Jose O; Williams, Diane L; Keller, Timothy A; Schipul, Sarah E; Cherkassky, Vladimir L; Minshew, Nancy J; Just, Marcel Adam

    2015-01-01

    Theory-of-mind (ToM), the ability to infer people's thoughts and feelings, is a pivotal skill in effective social interactions. Individuals with autism spectrum disorders (ASD) have been found to have altered ToM skills, which significantly impacts the quality of their social interactions. Neuroimaging studies have reported altered activation of the ToM cortical network, especially in adults with autism, yet little is known about the brain responses underlying ToM in younger individuals with ASD. This functional magnetic resonance imaging (fMRI) study investigated the neural mechanisms underlying ToM in high-functioning children and adolescents with ASD and matched typically developing (TD) peers. fMRI data were acquired from 13 participants with ASD and 13 TD control participants while they watched animations involving two "interacting" geometrical shapes. Participants with ASD showed significantly reduced activation, relative to TD controls, in regions considered part of the ToM network, the mirror network, and the cerebellum. Functional connectivity analyses revealed underconnectivity between frontal and posterior regions during task performance in the ASD participants. Overall, the findings of this study reveal disruptions in the brain circuitry underlying ToM in ASD at multiple levels, including decreased activation and decreased functional connectivity.

  18. Seeing More Than Human: Autism and Anthropomorphic Theory of Mind

    Directory of Open Access Journals (Sweden)

    Gray Atherton

    2018-04-01

    Full Text Available Theory of mind (ToM is defined as the process of taking another’s perspective. Anthropomorphism can be seen as the extension of ToM to non-human entities. This review examines the literature concerning ToM and anthropomorphism in relation to individuals with Autism Spectrum Disorder (ASD, specifically addressing the questions of how and why those on the spectrum both show an increased interest for anthropomorphism and may even show improved ToM abilities when judging the mental states of anthropomorphic characters. This review highlights that while individuals with ASD traditionally show deficits on a wide range of ToM tests, such as recognizing facial emotions, such ToM deficits may be ameliorated if the stimuli presented is cartoon or animal-like rather than in human form. Individuals with ASD show a greater interest in anthropomorphic characters and process the features of these characters using methods typically reserved for human stimuli. Personal accounts of individuals with ASD also suggest they may identify more closely with animals than other humans. It is shown how the social motivations hypothesized to underlie the anthropomorphizing of non-human targets may lead those on the spectrum to seek social connections and therefore gain ToM experience and expertise amongst unlikely sources.

  19. Theory of mind in emerging reading comprehension: A longitudinal study of early indirect and direct effects.

    Science.gov (United States)

    Atkinson, Lynette; Slade, Lance; Powell, Daisy; Levy, Joseph P

    2017-12-01

    The relation between children's theory of mind (ToM) and emerging reading comprehension was investigated in a longitudinal study over 2.5years. A total of 80 children were tested for ToM, decoding, language skills, and executive function (EF) at Time 1 (mean age=3;10 [years;months]). At Time 2 (mean age=6;03), children's word reading efficiency, language skills, and reading comprehension were measured. Mediation analysis showed that ToM at Time 1, when children were around 4years old, indirectly predicted Time 2 reading comprehension, when children were 6years old, via language ability after controlling for age, nonverbal ability, decoding, EF, and earlier language ability. Importantly, ToM at 4years also directly predicted reading comprehension 2.5years later at 6years. This is the first longitudinal study to show a direct contribution of ToM to reading comprehension in typical development. Findings are discussed in terms of the simple view of reading (SVR); ToM not only supports reading comprehension indirectly by facilitating language but also contributes to it directly over and above the SVR. The potential role of metacognition is considered when accounting for the direct contribution of early ToM to later reading comprehension. Copyright © 2017 Elsevier Inc. All rights reserved.

  20. From Fancy to Reason: Scaling Deaf and Hearing Children’s Understanding of Theory of Mind and Pretence

    Science.gov (United States)

    Peterson, Candida C.; Wellman, Henry M.

    2011-01-01

    We examined deaf and hearing children’s progression of steps in theory-of-mind (ToM) development including their understanding of social pretending. Ninety-three children (33 deaf; 60 hearing) aged 3 to 13 years were tested on a set of six closely-matched ToM tasks. Results showed that deaf children were delayed substantially behind hearing children in understanding pretending, false belief and other ToM concepts, in line with their delayed uptake of social pretend play. By using a scaling methodology, we confirmed previous evidence of a consistent five-step developmental progression for both groups. Moreover, by including social pretence understanding, both deaf and hearing children’s ToM sequences were shown to extend reliably to six sequential developmental steps. Finally and focally, even though both groups’ sequences were six steps long, the placement of pretence relative to other ToM milestones varied with hearing status. Deaf children understood social pretending at an earlier step in the ToM sequence than hearing children, albeit at a later chronological age. Theoretically, the findings are relevant to questions about how universal developmental progressions come together along with culturally-distinctive inputs and biological factors (such as hearing loss) to set the pace for ToM development. PMID:19998533

  1. A Developmental Perspective for Promoting Theory of Mind

    Science.gov (United States)

    Westby, Carol; Robinson, Lee

    2014-01-01

    Social neuroscience research has resulted in changing views of the theory of mind (ToM) construct. Theory of mind is no longer viewed as a unitary construct, but rather as a multidimensional construct comprising cognitive and affective ToM and interpersonal and intrapersonal ToM, each of which has differing neurophysiological/neuroanatomical…

  2. Article Molecular analysis of three FUT3 gene single nucleotide polymorphisms and their relationship with the lewis erythrocytary phenotype in a human population of japanese-ancestry living in Tomé Açu, a town in the Brazilian Amazon

    Directory of Open Access Journals (Sweden)

    Pablo Abdon da Costa Francez

    2007-03-01

    Full Text Available The Lewis blood group system involves two major antigens, Leª and Le b. Their antigenic determinants are not primary gene products but are synthesized by the transfer of sugar subunits to a precursory chain by a specific enzyme which is the product of the FUT3 gene (Lewis gene. The presence of three FUT3 gene single nucleotide polymorphisms (SNPs (59T > G; 508G > A and 1067T > A was related to the Lewis phenotype of erythrocytes from 185 individuals of Japanese ancestry living in the town of Tomé-Açu in the Brazilian Amazon region. This relationship was detected using a serological hemagglutination test and the Dot-ELISA assay along with the molecular technique PCR-RFLP. We found that the three SNPs investigated in this study only accounted for a proportion of the Lewis-negative phenotype of the erythrocytes.

  3. Theory of mind and psychiatry: an introduction.

    Science.gov (United States)

    Ang, Giap Kian; Pridmore, Saxby

    2009-04-01

    'Theory of mind' (ToM) arose from the study of primates and their social organization, and scholars in many fields - philosophy, anthropology, psychology, psychiatry and neuroscience - have contributed to this expanding topic. In this paper, we provide an overview of aspects of ToM of relevance to psychiatry. We briefly describe the origins of ToM in primates and humans and some relevant neurobiology, and then touch on possible contributions to psychopathology. We searched for articles on PubMed and Medline, using the terms 'theory of mind', 'mirror neuron system' and 'psychiatry'. There is evidence that ToM deficits are important in certain psychiatric disorders. While more research is required, an appreciation of ToM will have an impact on our further understanding and management of at least some mental disorders, including autism and schizophrenia.

  4. Not just a sum of its parts: How tasks of the theory of mind scale relate to executive function across time.

    Science.gov (United States)

    Doenyas, Ceymi; Yavuz, H Melis; Selcuk, Bilge

    2018-02-01

    There is a well-established relationship between theory of mind (ToM) and executive function (EF) during the preschool years. However, less is known about the concurrent and longitudinal relations between EF and specific tasks tapping different aspects of ToM. The current study investigated the ToM-EF relationship across 1 year in 3- to 5-year-old Turkish children using the ToM battery of Wellman and Liu (2004), which measures understanding of diverse desires (DD), diverse beliefs (DB), knowledge access (KA), contents false belief (CFB), explicit false belief (EFB), and hidden emotion (HE). This battery has not yet been used in its entirety to test the predictive relations between ToM and EF. We used peg-tapping and day-night tasks to measure EF. Our sample comprised 150 Turkish preschool children (69 girls) aged 36-60 months at Time 1 (T1) and 49-73 months at Time 2 (T2). Using the ToM composite with all six tasks, when child's age, receptive language, and T1 ability level (EF or ToM) were controlled, T1 EF significantly predicted T2 ToM, whereas T1 ToM did not predict T2 EF. Among DD, DB, KA, false belief understanding (FBU: the composite score of CFB and EFB), and HE, only KA and FBU were significantly associated with EF at T1 and T2. Further regression analyses showed that KA did not have a predictive relationship with EF. Instead, FBU drove the predictive EF-ToM relationship across time. Thus, in Turkish children, earlier EF predicts later ToM, but especially the FBU component, in this well-validated battery. Copyright © 2017. Published by Elsevier Inc.

  5. Origins of terrestrial organic matter in surface sediments of the East China Sea shelf

    Science.gov (United States)

    Zhang, Hailong; Xing, Lei; Zhao, Meixun

    2017-10-01

    Terrestrial organic matter (TOM) is an important component of marine sedimentary OM, and revealing the origins and transport mechanisms of TOM to the East China Sea (ECS) is important for understanding regional carbon cycle. A novel approach combining molecular proxies and compound-specific carbon isotopes is used to quantitatively constrain the origins and transport mechanisms of TOM in surface sediments from the ECS shelf. The content of terrestrial biomarkers of (C27+C29+C31) n-alkanes (52 to 580 ng g-1) revealed a seaward decreasing trend, the δ13CTOC values (-20.6‰ to -22.7‰) were more negative near the coast, and the TMBR (terrestrial and marine biomarker ratio) values (0.06 to 0.40) also revealed a seaward decreasing trend. These proxies all indicated more TOM (up to 48%) deposition in the coastal areas. The Alkane Index, the ratio of C29/(C29+C31) n-alkanes indicated a higher proportion of grass vegetation in the coastal area; While the δ13C values of C29 n-alkane (-29.3‰ to -33.8‰) indicated that terrestrial plant in the sediments of the ECS shelf were mainly derived from C3 plants. Cluster analysis afforded detailed estimates of different-sourced TOM contributions and transport mechanisms. TOM in the Zhejiang-Fujian coastal area was mostly delivered by the Changjiang River, and characterized by higher %TOM (up to 48%), higher %C3 plant OM (68%-85%) and higher grass plant OM (56%-61%); TOM in the mid-shelf area was mostly transported by aerosols, and characterized by low %TOM (less than 17%), slightly lower C3 plant OM (56%-72%) and lower grass plant OM (49%-55%).

  6. The Children's Social Understanding Scale: Construction and Validation of a Parent-Report Measure for Assessing Individual Differences in Children's Theories of Mind

    Science.gov (United States)

    Tahiroglu, Deniz; Moses, Louis J.; Carlson, Stephanie M.; Mahy, Caitlin E. V.; Olofson, Eric L.; Sabbagh, Mark A.

    2014-01-01

    Children's theory of mind (ToM) is typically measured with laboratory assessments of performance. Although these measures have generated a wealth of informative data concerning developmental progressions in ToM, they may be less useful as the sole source of information about individual differences in ToM and their relation to other facets of…

  7. Intra-Articular Lubricin Gene Therapy for Post-Traumatic Arthritis

    Science.gov (United States)

    2017-09-01

    MaxSi TM Graft Granules in a Rabbit Metaphyseal Defect Model Sponsor Agency: SIRAKOSS Sponsor Contact:: Dr. Tom Buckland, Chief Strategy Officer, +44...Dr. Tom Buckland, Chief Strategy Officer, +44-7545-840504, tom.buckland@sirakoss.com 02/01/2016–09/30/2016, 02/01/2016–09/30/2016, 02/01/2016–06

  8. Individual differences in executive function and central coherence predict developmental changes in theory of mind in autism.

    Science.gov (United States)

    Pellicano, Elizabeth

    2010-03-01

    There is strong evidence to suggest that individuals with autism show atypicalities in multiple cognitive domains, including theory of mind (ToM), executive function (EF), and central coherence (CC). In this study, the longitudinal relationships among these 3 aspects of cognition in autism were investigated. Thirty-seven cognitively able children with an autism spectrum condition were assessed on tests targeting ToM (false-belief prediction), EF (planning ability, cognitive flexibility, and inhibitory control), and CC (local processing) at intake and again 3 years later. Time 1 EF and CC skills were longitudinally predictive of change in children's ToM test performance, independent of age, language, nonverbal intelligence, and early ToM skills. Predictive relations in the opposite direction were not significant, and there were no developmental links between EF and CC. Rather than showing problems in ToM, EF and CC as co-occurring and independent atypicalities in autism, these findings suggest that early domain-general skills play a critical role in shaping the developmental trajectory of children's ToM.

  9. Autistic traits and positive psychotic experiences modulate the association of psychopathic tendencies with theory of mind in opposite directions.

    Science.gov (United States)

    Gillespie, Steven M; Mitchell, Ian J; Abu-Akel, Ahmad M

    2017-07-25

    Various clinical disorders, including psychopathy, and autism and schizophrenia spectrum disorders, have been linked with impairments in Theory of Mind (ToM). However, although these conditions can co-occur in the same individual, the effect of their inter-play on ToM abilities has not been investigated. Here we assessed ToM abilities in 55 healthy adults while performing a naturalistic ToM task, requiring participants to watch a short film and judge the actors' mental states. The results reveal for the first time that autistic traits and positive psychotic experiences interact with psychopathic tendencies in opposite directions to predict ToM performance-the interaction of psychopathic tendencies with autism traits was associated with a decrement in performance, whereas the interaction of psychopathic tendencies and positive psychotic experiences was associated with improved performance. These effects were specific to cognitive rather than affective ToM. These results underscore the importance of the simultaneous assessment of these dimensions within clinical settings. Future research in these clinical populations may benefit by taking into account such individual differences.

  10. Theory of Mind Predicts Emotion Knowledge Development in Head Start Children.

    Science.gov (United States)

    Seidenfeld, Adina M; Johnson, Stacy R; Cavadel, Elizabeth Woodburn; Izard, Carroll E

    2014-10-01

    Emotion knowledge (EK) enables children to identify emotions in themselves and others and its development facilitates emotion recognition in complex social situations. Social-cognitive processes, such as theory of mind (ToM), may contribute to developing EK by helping children realize the inherent variability associated with emotion expression across individuals and situations. The present study explored how ToM, particularly false belief understanding, in preschool predicts children's developing EK in kindergarten. Participants were 60 3- to 5-year-old Head Start children. ToM and EK measures were obtained from standardized child tasks. ToM scores were positively related to performance on an EK task in kindergarten after controlling for preschool levels of EK and verbal ability. Exploratory analyses provided preliminary evidence that ToM serves as an indirect effect between verbal ability and EK. Early intervention programs may benefit from including lessons on ToM to help promote socio-emotional learning, specifically EK. This consideration may be the most fruitful when the targeted population is at-risk.

  11. Plasticity in older adults' theory of mind performance: the impact of motivation.

    Science.gov (United States)

    Zhang, Xin; Lecce, Serena; Ceccato, Irene; Cavallini, Elena; Zhang, Linfang; Chen, Tianyong

    2017-09-08

    Recently, motivation has been found to attenuate the age-related decline in Theory of Mind (ToM) performance (i.e. faux pas recognition). However, whether or not this effect could be generalized to other ToM tasks is still unknown. In the present study, we investigated whether and how motivation could enhance older adults' performance and reduce age differences in ToM tasks (Faux Pas vs. Animation task) that differ in familiarity. Following a previous paradigm, 171 Chinese adults (87 younger adults and 84 older adults) were recruited, and we experimentally manipulated the level of perceived closeness between participants and the experimenter before administering the ToM tasks in order to enhance participants' motivation. Results showed that, for the Faux Pas task, we replicated previous findings such that older adults under the enhanced motivation conditions performed equally well as younger adults. Conversely, for the Animation task, younger adults outperformed older adults, regardless of motivation. These results indicate that motivation can enhance older adults' performance in ToM tasks, however, this beneficial effect cannot be generalized across ToM tasks.

  12. Evaluation of the transfer and the accumulation of microcystins in tomato (Solanum lycopersicum cultivar MicroTom) tissues using a cyanobacterial extract containing microcystins and the radiolabeled microcystin-LR ("1"4C-MC-LR)

    International Nuclear Information System (INIS)

    Corbel, Sylvain; Mougin, Christian; Nélieu, Sylvie; Delarue, Ghislaine; Bouaïcha, Noureddine

    2016-01-01

    Microcystins are the most common cyanotoxins and may be expected wherever blooms of cyanobacteria occur in surface waters. Their persistence both in the irrigation water and in the soil can lead to their transfer and bioaccumulation into agricultural plants. The aim of this work was to investigate microcystin accumulation in Solanum lycopersicum cultivar MicroTom. The plant was exposed to either Microcystis aeruginosa crude extracts containing up to 100 μg eq. MC-LR L"−"1 in a soil–plant system for 90 days or pure radiolabeled "1"4C-MC-LR in a hydroponic condition for 48 h. Toxin bioaccumulation in the soil and different plant tissues was assessed both by the PP2A inhibition assay and by liquid chromatography-mass spectrometry (LC/MS/MS). After 90 days of exposure, microcystins persisted in the soil and their free extractable concentrations accumulated were very low varying between 1.6 and 3.9 μg eq. MC-LR kg"−"1 DW. Free MC-LR was detected only in roots and leaves with concentrations varying between 4.5 and 8.1 μg kg"−"1 DW and between 0.29 and 0.55 μg kg"−"1 DW, respectively. By using radioactivity ("1"4C-MC-LR), the results have reported a growing accumulation of toxins within the organs roots > leaves > stems and allowed them to confirm the absence of MC-LR in fruits after 48 h of exposure. The bioconcentration factor (BCF) was 13.6 in roots, 4.5 in leaves, and 1.4 in stems. On the other hand, the results highlight the presence of two radioactive fractions in different plant tissues. The non-extractable fraction of radioactivity, corresponding to the covalently bound MC-LR, was higher than that of the extractable fraction only in roots and leaves reaching 56% and 71% of the total accumulated toxin, respectively. Therefore, results raise that monitoring programs must monitor the presence of MCs in the irrigation water to avoid the transfer and accumulation of these toxins in crops. - Graphical abstract: Bioconcentration factors in organs of the

  13. Evaluation of the transfer and the accumulation of microcystins in tomato (Solanum lycopersicum cultivar MicroTom) tissues using a cyanobacterial extract containing microcystins and the radiolabeled microcystin-LR ({sup 14}C-MC-LR)

    Energy Technology Data Exchange (ETDEWEB)

    Corbel, Sylvain [INRA, UMR1402 ECOSYS, F-78850 Thiverval-Grignon (France); AgroParisTech, UMR1402 ECOSYS, F-78850 Thiverval-Grignon (France); Laboratoire Ecologie, Systématique et Evolution, UMR8079, Univ. Paris-Sud/CNRS/AgroParisTech, Université Paris-Sud, F-91405 Orsay (France); Mougin, Christian; Nélieu, Sylvie; Delarue, Ghislaine [INRA, UMR1402 ECOSYS, F-78850 Thiverval-Grignon (France); AgroParisTech, UMR1402 ECOSYS, F-78850 Thiverval-Grignon (France); Bouaïcha, Noureddine, E-mail: noureddine.bouaicha@u-psud.fr [Laboratoire Ecologie, Systématique et Evolution, UMR8079, Univ. Paris-Sud/CNRS/AgroParisTech, Université Paris-Sud, F-91405 Orsay (France)

    2016-01-15

    Microcystins are the most common cyanotoxins and may be expected wherever blooms of cyanobacteria occur in surface waters. Their persistence both in the irrigation water and in the soil can lead to their transfer and bioaccumulation into agricultural plants. The aim of this work was to investigate microcystin accumulation in Solanum lycopersicum cultivar MicroTom. The plant was exposed to either Microcystis aeruginosa crude extracts containing up to 100 μg eq. MC-LR L{sup −1} in a soil–plant system for 90 days or pure radiolabeled {sup 14}C-MC-LR in a hydroponic condition for 48 h. Toxin bioaccumulation in the soil and different plant tissues was assessed both by the PP2A inhibition assay and by liquid chromatography-mass spectrometry (LC/MS/MS). After 90 days of exposure, microcystins persisted in the soil and their free extractable concentrations accumulated were very low varying between 1.6 and 3.9 μg eq. MC-LR kg{sup −1} DW. Free MC-LR was detected only in roots and leaves with concentrations varying between 4.5 and 8.1 μg kg{sup −1} DW and between 0.29 and 0.55 μg kg{sup −1} DW, respectively. By using radioactivity ({sup 14}C-MC-LR), the results have reported a growing accumulation of toxins within the organs roots > leaves > stems and allowed them to confirm the absence of MC-LR in fruits after 48 h of exposure. The bioconcentration factor (BCF) was 13.6 in roots, 4.5 in leaves, and 1.4 in stems. On the other hand, the results highlight the presence of two radioactive fractions in different plant tissues. The non-extractable fraction of radioactivity, corresponding to the covalently bound MC-LR, was higher than that of the extractable fraction only in roots and leaves reaching 56% and 71% of the total accumulated toxin, respectively. Therefore, results raise that monitoring programs must monitor the presence of MCs in the irrigation water to avoid the transfer and accumulation of these toxins in crops. - Graphical abstract: Bioconcentration

  14. Vaid üks on taevas / Kaire Maimets-Volt

    Index Scriptorium Estoniae

    Maimets, Kaire, 1977-

    2006-01-01

    Mängufilmist "Taevas" ("Heaven") : režissöör Tom Tykwer, stsenaristid Krzysztof Piesiewicz ja Krzysztof Kieslowski, peaosas Cate Blanchett : Saksamaa - Itaalia - USA - Prantsusmaa - Suurbritannia 2002. Originaalmuusika Tom Tykwer, valmismuusika Arvo Pärt ("Aliinale", "Peegel peeglis", "Variatsioonid Arinushka tervenemise puhul"). Esilinastus 6. II 2002 Berliini rahvusvahelisel filmifestivalil. Artikli lõpus Tom Tykwerist ja tema filmograafia

  15. Using the Theory of Mind Inventory to Detect a Broad Range of Theory of Mind Challenges in Children with Hearing Loss: A Pilot Study

    Science.gov (United States)

    Hutchins, Tiffany L.; Allen, Lyndsey; Schefer, Maggie

    2017-01-01

    Traditional child-performance measures of theory of mind (ToM) are associated with several limitations. The Theory of Mind Inventory-2 (ToMI-2) is a new broadband caregiver-informant measure designed to tap children's ToM competence. The purposes of this pilot study were to (1) gather preliminary data to explore the scope of the ToM challenges…

  16. Theory of Mind and Executive Function in Preschoolers with Typical Development versus Intellectually Able Preschoolers with Autism Spectrum Disorder

    Science.gov (United States)

    Kimhi, Yael; Shoam-Kugelmas, Dana; Agam Ben-Artzi, Galit; Ben-Moshe, Inbal; Bauminger-Zviely, Nirit

    2014-01-01

    Children with autism spectrum disorder (ASD) have difficulties in theory of mind (ToM) and executive function (EF), which may be linked because one domain (EF) affects the other (ToM). Group differences (ASD vs. typical development) were examined in both cognitive domains, as well as EF's associations and regressions with ToM. Participants…

  17. Does Theory of Mind Performance Differ in Children with Early-Onset and Regressive Autism?

    Science.gov (United States)

    Matthews, Nicole L.; Goldberg, Wendy A.; Lukowski, Angela F.; Osann, Kathryn; Abdullah, Maryam M.; Ly, Agnes R.; Thorsen, Kara; Spence, M. Anne

    2012-01-01

    A deficit in theory of mind (ToM), or the ability to infer the mental states of others, has been implicated as one of the major characteristics of Autism Spectrum Disorder (ASD); however, little attention has been devoted to possible differences in ToM ability within ASD. The current study examined ToM performance in children with early-onset…

  18. [Impaired theory of mind in anorexia nervosa].

    Science.gov (United States)

    Gál, Zita; Egyed, Katalin; Pászthy, Bea; Németh, Dezsö

    2011-01-01

    Anorexia nervosa (AN) is a severe mental illness, which is characterized by a continuously growing occurrence in the population and by the shift of the onset for earlier ages. The understanding of factors playing role in AN and the importance of effective prevention is an essential issue in science as well as in the society. AN also affects the social domain of life, patients with AN may exhibit impaired social interaction, social isolation, difficulties in emotion recognition and egocentric thinking in cognitive processing. Therefore, the aim of present study was to investigate the theory of mind (ToM) deficits is anorexia nervosa. Although previous studies have reported ToM deficits in autism and in schizophrenia, the number of studies investigating ToM functioning in eating disorders are particularly low. Even though ToM difficulties, such as the affective ToM impairments were found in AN, however, the evidence of cognitive ToM deficits in anorexia patients is still lacking. Twenty anorexia nervosa patients and 20 healthy control adolescent girls participated in the experiment. EDI, BAT, Fallon-Rozin Test and Anamoprhic Micro Body Image Assesment Programme questionnaires and body-image tests were applied to discriminate anorexia nervosa group from healthy control group. The Hungarian version of Faux Pas Recognition Test was applied to evaluate ToM functioning. Compared to healthy control group, impairment in ToM functioning was found in AN group, especially in affective mental state attribution. Our results can raise new aspects for research, therapy and prevention of anorexia nervosa.

  19. Sci-Thur PM – Brachytherapy 02: Positional accuracy in Pd-103 permanent breast seed implant (PBSI) brachytherapy at the Tom Baker Cancer Centre (TBCC)

    Energy Technology Data Exchange (ETDEWEB)

    Frederick, Amy; Watt, Elizabeth; Peacock, Michael; Husain, Siraj; Meyer, Tyler; Roumeliotis, Michael [University of Calgary, Tom Baker Cancer Centre (Canada)

    2016-08-15

    Purpose: This retrospective study aims to quantify the positional accuracy of seed delivery in permanent breast seed implant (PBSI) brachytherapy at the Tom Baker Cancer Centre (TBCC). Methods: Treatment planning and post-implant CT scans for 5 patients were rigidly registered using the MIM Symphony™ software (MIM Software, Cleveland, OH) and used to evaluate differences between planned and implanted seed positions. Total and directional seed displacements were calculated for each patient in a clinically relevant ‘needle coordinate system’, defined relative to the angle of fiducial needle insertion. Results: The overall average total seed displacement was 10±8 mm. Systematic seed displacements were observed in individual patients and the magnitude and direction of these offsets varied among patients. One patient showed a significant directional seed displacement in the shallow-deep direction compared with the other four patients. With the exception of this one patient outlier, no significant systematic directional displacements in the needle coordinate system were observed for this cohort; the average directional displacements were −1±5 mm, 2±3 mm, and −2±4 mm in the shallow-deep, up-down, and right-left directions respectively. Conclusion: With the exception of one patient outlier, the magnitude of seed displacements were relatively consistent among patients. The results indicate that the shallow-deep direction possesses the largest uncertainty for the seed delivery method used at the TBCC. The relatively large uncertainty in seed placement in this direction is expected, as this is the direction of needle insertion. Further work will involve evaluating deflections of delivered needle tracks from their planned positions.

  20. Theory of Mind in Children With Specific Language Impairment: A Systematic Review and Meta-Analysis.

    Science.gov (United States)

    Nilsson, Kristine Kahr; de López, Kristine Jensen

    2016-01-01

    The relation between language and theory of mind (ToM) has been debated for more than two decades. In a similar vein, ToM has been examined in children with specific language impairment (SLI), albeit with inconsistent results. This meta-analysis of 17 studies with 745 children between the ages of 4 and 12 found that children with SLI had substantially lower ToM performance compared to age-matched typically developing children (d = .98). This effect size was not moderated by age and gender. By revealing that children with SLI have ToM impairments, this finding emphasizes the need for further investigation into the developmental interface between language and ToM as well as the extended consequences of atypical language development. © 2015 The Authors. Child Development © 2015 Society for Research in Child Development, Inc.

  1. The relationship between joint attention and theory of mind in neurotypical adults.

    Science.gov (United States)

    Shaw, Jordan A; Bryant, Lauren K; Malle, Bertram F; Povinelli, Daniel J; Pruett, John R

    2017-05-01

    Joint attention (JA) is hypothesized to have a close relationship with developing theory of mind (ToM) capabilities. We tested the co-occurrence of ToM and JA in social interactions between adults with no reported history of psychiatric illness or neurodevelopmental disorders. Participants engaged in an experimental task that encouraged nonverbal communication, including JA, and also ToM activity. We adapted an in-lab variant of experience sampling methods (Bryant et al., 2013) to measure ToM during JA based on participants' subjective reports of their thoughts while performing the task. This experiment successfully elicited instances of JA in 17/20 dyads. We compared participants' thought contents during episodes of JA and non-JA. Our results suggest that, in adults, JA and ToM may occur independently. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  2. The mind behind the message: Advancing theory of mind scales for typically developing children, and those with deafness, autism, or Asperger Syndrome

    Science.gov (United States)

    Peterson, Candida C.; Wellman, Henry M.; Slaughter, Virginia

    2013-01-01

    Children aged 3 to 12 years (n=184) with typical development, deafness, autism or Asperger Syndrome took a series of theory-of-mind (ToM) tasks to confirm and extend previous developmental scaling evidence. A new sarcasm task, in the format of Wellman and Liu’s (2004) 5-step ToM scale, added a statistically reliable sixth step to the scale for all diagnostic groups. A key previous finding, divergence in task sequencing for children with autism, was confirmed. Comparisons among diagnostic groups, controlling age and language ability, showed that typical developers mastered the six ToM steps ahead of each of the three disabled groups, with implications for ToM theories. The final (sarcasm) task challenged even nondisabled 9-year-olds, demonstrating the new scale’s sensitivity to post-preschool ToM growth. PMID:22304467

  3. Making sense of self-conscious emotion: linking theory of mind and emotion in children with autism.

    Science.gov (United States)

    Heerey, Erin A; Keltner, Dacher; Capps, Lisa M

    2003-12-01

    Self-conscious emotions such as embarrassment and shame are associated with 2 aspects of theory of mind (ToM): (a) the ability to understand that behavior has social consequences in the eyes of others and (b) an understanding of social norms violations. The present study aimed to link ToM with the recognition of self-conscious emotion. Children with and without autism identified facial expressions conscious of self-conscious and non-self-conscious emotions from photographs. ToM was also measured. Children with autism performed more poorly than comparison children at identifying self-conscious emotions, though they did not differ in the recognition of non-self-conscious emotions. When ToM ability was statistically controlled, group differences in the recognition of self-conscious emotion disappeared. Discussion focused on the links between ToM and self-conscious emotion.

  4. Affective and cognitive theory of mind abilities in youth with borderline personality disorder or major depressive disorder.

    Science.gov (United States)

    Tay, Sarah-Ann; Hulbert, Carol A; Jackson, Henry J; Chanen, Andrew M

    2017-09-01

    Theory of mind (ToM) is an important social cognitive ability that has been investigated in BPD, with inconsistent findings indicating impaired, comparable, and enhanced ToM in BPD. This study aimed to clarify and extend previous findings by investigating affective and cognitive ToM abilities in youth early in the course of BPD, by including a clinical comparison group of youth with major depressive disorder (MDD). Female participants aged 15-24 years diagnosed with BPD (n = 41) or MDD (n = 37) completed the Reading the Mind in the Eyes Test (RMET) and Happé's Cartoon Task, measures of affective and cognitive dimensions of ToM, respectively. The BPD group performed significantly worse than the MDD group on the affective ToM task, even after controlling for age, intelligence and depressive symptoms. Results for cognitive ToM were not significantly different. Finding of poorer performance on a measure of affective ToM, in BPD youth, relative to youth with MDD early in the course of BPD suggest a developmental failure of sociocognitive abilities needed for mentalising and which are theorised as giving rise to core features of BPD. Future research should employ more naturalistic paradigms to study social cognition and should assess individuals even earlier in the course of BPD. Copyright © 2017. Published by Elsevier B.V.

  5. Executive function predicts theory of mind but not social verbal communication in school-aged children with autism spectrum disorder.

    Science.gov (United States)

    Kouklari, Evangelia-Chrysanthi; Tsermentseli, Stella; Auyeung, Bonnie

    2018-05-01

    The association between Executive Function (EF) and Theory of Mind (ToM) in autism spectrum disorder (ASD) has been mainly investigated using false belief tasks, whilst less is known about the EF effect on other ToM facets. Furthermore, the role EF plays in social communication in ASD is mainly assessed using parent-report EF ratings rather than direct assessment. The aim of this study was to shed more light on the effect of performance-based EF measures on ToM and social communication in middle childhood in ASD relative to neurotypical controls. Cross-sectional data were collected from 64 matched, school-aged children with and without ASD (8-12 years old), tested on measures of EF (inhibition, working memory, cognitive flexibility), ToM mental state/emotion recognition and social verbal communication. Significant group differences were observed only in selective EF skills (inhibition &cognitive flexibility) and social verbal communication. EF working memory contributed to the explained variance of ToM but not social verbal communication in middle childhood. These findings suggest that EF and ToM are still associated in middle childhood and EF may be a crucial predictor of ToM across childhood in ASD. Implications are discussed regarding the social-cognitive impairment relationship in ASD. Copyright © 2018 Elsevier Ltd. All rights reserved.

  6. Are “Theory of Mind” Skills in People with Epilepsy Related to How Stigmatised They Feel? An Exploratory Study

    Science.gov (United States)

    Robinson, A.

    2016-01-01

    Feelings of stigma are one of the main burdens reported by people with epilepsy (PWE). Adults with temporal or frontal lobe epilepsy and children with idiopathic generalised epilepsy are at risk of Theory of Mind (ToM) deficits. ToM refers to social cognitive skills, including the ability to understand the thoughts, intentions, beliefs, and emotions of others. It has been proffered that ToM deficits may contribute to the feelings of stigma experienced by PWE. In this study we tested this for the first time. We also determined the association between clinical and demographic factors and ToM performance. Five hundred and three PWE were recruited via epilepsy organisations and completed measures online. Feelings of stigma were measured using Jacoby's Stigma Scale, whilst the Reading the Mind in the Eyes Test and the Faux Pas Test measured ToM. The median age of participants was 37 years, their median years living with epilepsy were 15, and 70% had experienced seizures in the prior 12 months. Feelings of stigma held a negligible, negative, and nonsignificant association with ToM performance (r s  −0.02 and −0.05). Our results indicate that the ToM model for understanding epilepsy stigma has limited utility and alternative approaches to understanding and addressing epilepsy-related stigma are required. PMID:27635114

  7. Attachment and thought problems in an adolescent inpatient sample: The mediational role of theory of mind.

    Science.gov (United States)

    Hart, Jessica R; Venta, Amanda; Sharp, Carla

    2017-10-01

    Previous research has documented increased incidence of insecure attachment and theory of mind (ToM) deficits in individuals experiencing psychotic disorders. ToM has been theorized as a possible mediator of the relation between attachment and psychosis (Korver-Nieberg et al., 2014). The current study sought to extend this area of research to adolescents for the first time by examining adolescent-parent attachment and ToM in inpatient adolescents. Participants were 362 inpatient adolescents and their parents; participants completed the Child Attachment Interview, Movie for the Assessment of Social Cognition, Youth Self Report, and Child Behavior Checklist. Bivariate correlations indicated that attachment coherence (a marker of security) was significantly and positively correlated with ToM abilities, and that low attachment coherence and poor ToM performance were each associated with increased youth- and parent-reported thought problems. Mediational models indicated that ToM mediated the relation between insecure attachment and thought problems according to both parent- and self-report. The results of the current study provide support for a model in which impairments in ToM contribute to the frequently documented association between insecure attachment and emerging psychotic symptoms. Theoretical and clinical implications of these results are discussed, including the potential support for ToM-based interventions for early psychotic symptoms. Copyright © 2017 Elsevier Inc. All rights reserved.

  8. Simple Mindreading Abilities Predict Complex Theory of Mind: Developmental Delay in Autism Spectrum Disorders

    Science.gov (United States)

    Pino, Maria Chiara; Mazza, Monica; Mariano, Melania; Peretti, Sara; Dimitriou, Dagmara; Masedu, Francesco; Valenti, Marco; Franco, Fabia

    2017-01-01

    Theory of mind (ToM) is impaired in individuals with autism spectrum disorders (ASD). The aims of this study were to: (i) examine the developmental trajectories of ToM abilities in two different mentalizing tasks in children with ASD compared to TD children; and (ii) to assess if a ToM simple test known as eyes-test could predict performance on…

  9. The relationship between theory of mind and autobiographical memory in high-functioning autism and Asperger syndrome.

    Science.gov (United States)

    Adler, Noga; Nadler, Benny; Eviatar, Zohar; Shamay-Tsoory, Simone G

    2010-06-30

    The relationship between theory of mind (ToM) and autobiographical memory (AM) in high-functioning autism (HFA) and Asperger syndrome (AS) has never been investigated. Here, we show that ToM abilities could be predicted by levels of AM in HFA and AS as compared to controls, suggesting that difficulties in AM are closely related to ToM impairments in HFA and AS.

  10. Assessment of genetic diversity in Indian rice germplasm (Oryza ...

    Indian Academy of Sciences (India)

    2013-12-11

    Dec 11, 2013 ... 3Indian Agricultural Research Institute, Rice Breeding and Genetics Research Centre, Aduthurai 612 101, India ..... Govind Ballabh Pant University of Agriculture and Technology; IRRI, Inter- ..... 83–91, Arkansas Agricultural Experiment Station, ... Temnykh S., Park D. W., Ayres N., Cartinhour S., Hauck N.,.

  11. Metabolism of materials by the construction sector in developing countries : Costa Rica as a case study

    NARCIS (Netherlands)

    Abarca Guerrero, L.; Scheublin, F.J.M.; Egmond - de Wilde De Ligny, van E.L.C.; Lambert, A.J.D.

    2009-01-01

    Production practices require large amounts of materials and are not likely to be sustained without large implication for the environment. Materials and energy are put together in order to produce goods and the total of these physical processes have been referred by Ayres and Simons as "Industrial

  12. Reglas supletivas “sancionatorias” en el derecho de contratos colombiano: el caso del contrato de transporte

    Directory of Open Access Journals (Sweden)

    Daniel A. Monroy C.

    2016-06-01

    Full Text Available A finales de la década de 1980, Ayres y Gertner propusieron una controversial teoría sobre cómo integrar el contenido de lagunas en contratos incompletos, acuñando la noción de “penalty default rule” (regla supletiva sancionatoria para referirse a aquella regla que “sanciona” el silencio de las partes integrando al contrato una regla supletiva que “no” coincide con lo que la mayoría de las partes hubiesen querido. Bajo esta premisa, el artículo pretende demostrar que dichas reglas supletivas sancionatorias existen en el derecho de contratos colombiano. Así, (I propone una metodología para identificar situaciones contractuales hipotéticas donde conviene establecer reglas supletivas sancionatorias; (II somete a prueba la metodología a la luz del principal caso de estudio descrito por Ayres y Gertner, y (III replica la metodología con un caso propio del derecho de contratos colombiano.

  13. COĞRAFYA EĞİTİMİNDE FİZİKİ COĞRAFYA ÖĞRETİMİ İÇİN BİR ROTA ÖNERİSİ: ÇATALCA YARIMADASI BATISI, İSTANBUL

    OpenAIRE

    TUNA, FİKRET; SARIKAYA, MEHMET

    2014-01-01

    ÖZETSaha çalışması coğrafyanın en önemli öğretim metotlarından biridir ve coğrafya bilimini ve eğitimini saha çalışmasından ayrı düşünmek mümkün değildir. Ayrıca, saha çalışmaları, coğrafya eğitimine çok çeşitli katkılar sağlamaktadır. Bu çalışmanın temel amacı, coğrafya eğitimcilerine çeşitli fiziki coğrafya konularının öğretimi ile ilgili konularda faydalanabilecekleri örnek saha çalışması güzergâhı ve inceleme sahaları ve bunlarla ilgili bilgiler sunmaktır. Böylece, ihtiyaç duyan öğretmen ...

  14. Videnskabsretorik eller tom retorik

    DEFF Research Database (Denmark)

    Jensen, Leif Becker

    2005-01-01

    Artiklen omhandler videnskabsretorik såvel i den videnskabelige undersøgelse som i fremlæggelsen inden for forskellige paradigmer, herunder argumetnation set i lyset af Toulmins argumentationsmodel....

  15. Response to Tom Cobb

    Science.gov (United States)

    Nation, Paul

    2016-01-01

    In this article Paul Nation responds to Thomas Cobb's "Numbers or Numerology? A Response to Nation (2014) and McQuillan (2016)" (EJ1117024). Nation begins by clarifying his own position on vocabulary learning and goes on to highlight points made in Cobb's article with which he is in agreement, while drawing from his 2014 article,…

  16. Trouble in Toms River

    Science.gov (United States)

    Lugg, Catherine A.; Tooms, Autumn K.

    2011-01-01

    Drawing on a recent New Jersey Supreme Court decision (2007), this case addresses a school district's responsibility regarding homophobic bullying, school culture, and the rights of lesbian, gay, bisexual, and transgender students to be free of discrimination.

  17. Uncovering the neuroanatomical correlates of cognitive, affective and conative theory of mind in paediatric traumatic brain injury: a neural systems perspective.

    Science.gov (United States)

    Ryan, Nicholas P; Catroppa, Cathy; Beare, Richard; Silk, Timothy J; Hearps, Stephen J; Beauchamp, Miriam H; Yeates, Keith O; Anderson, Vicki A

    2017-09-01

    Deficits in theory of mind (ToM) are common after neurological insult acquired in the first and second decade of life, however the contribution of large-scale neural networks to ToM deficits in children with brain injury is unclear. Using paediatric traumatic brain injury (TBI) as a model, this study investigated the sub-acute effect of paediatric traumatic brain injury on grey-matter volume of three large-scale, domain-general brain networks (the Default Mode Network, DMN; the Central Executive Network, CEN; and the Salience Network, SN), as well as two domain-specific neural networks implicated in social-affective processes (the Cerebro-Cerebellar Mentalizing Network, CCMN and the Mirror Neuron/Empathy Network, MNEN). We also evaluated prospective structure-function relationships between these large-scale neural networks and cognitive, affective and conative ToM. 3D T1- weighted magnetic resonance imaging sequences were acquired sub-acutely in 137 children [TBI: n = 103; typically developing (TD) children: n = 34]. All children were assessed on measures of ToM at 24-months post-injury. Children with severe TBI showed sub-acute volumetric reductions in the CCMN, SN, MNEN, CEN and DMN, as well as reduced grey-matter volumes of several hub regions of these neural networks. Volumetric reductions in the CCMN and several of its hub regions, including the cerebellum, predicted poorer cognitive ToM. In contrast, poorer affective and conative ToM were predicted by volumetric reductions in the SN and MNEN, respectively. Overall, results suggest that cognitive, affective and conative ToM may be prospectively predicted by individual differences in structure of different neural systems-the CCMN, SN and MNEN, respectively. The prospective relationship between cerebellar volume and cognitive ToM outcomes is a novel finding in our paediatric brain injury sample and suggests that the cerebellum may play a role in the neural networks important for ToM. These findings are

  18. Cognitive and affective theory of mind in dementia with Lewy bodies and Alzheimer's disease.

    Science.gov (United States)

    Heitz, Camille; Noblet, Vincent; Phillipps, Clélie; Cretin, Benjamin; Vogt, Natacha; Philippi, Nathalie; Kemp, Jennifer; de Petigny, Xavier; Bilger, Mathias; Demuynck, Catherine; Martin-Hunyadi, Catherine; Armspach, Jean-Paul; Blanc, Frédéric

    2016-03-16

    Theory of mind (ToM) refers to the ability to attribute mental states, thoughts (cognitive component) or feelings (affective component) to others. This function has been studied in many neurodegenerative diseases; however, to our knowledge, no studies investigating ToM in dementia with Lewy bodies (DLB) have been published. The aim of our study was to assess ToM in patients with DLB and to search for neural correlates of potential deficits. Thirty-three patients with DLB (DLB group) and 15 patients with Alzheimer's disease (AD group), all in the early stage of the disease, as well as 16 healthy elderly control subjects (HC group), were included in the study. After a global cognitive assessment, we used the Faux Pas Recognition (FPR) test, the Reading the Mind in the Eyes (RME) test and Ekman's Facial Emotion Recognition test to assess cognitive and affective components of ToM. Patients underwent cerebral 3-T magnetic resonance imaging, and atrophy of grey matter was analysed using voxel-based morphometry. We performed a one-sample t test to investigate the correlation between each ToM score and grey matter volume and a two-sample t test to compare patients with DLB impaired with those non-impaired for each test. The DLB group performed significantly worse than the HC group on the FPR test (P = 0.033) and the RME test (P = 0.015). There was no significant difference between the AD group and the HC group or between the DLB group and the AD group. Some brain regions were associated with ToM impairments. The prefrontal cortex, with the inferior frontal cortex and the orbitofrontal cortex, was the main region, but we also found correlations with the temporoparietal junction, the precuneus, the fusiform gyrus and the insula. This study is the first one to show early impairments of ToM in DLB. The two cognitive and affective components both appear to be affected in this disease. Among patients with ToM difficulties, we found atrophy in brain regions classically

  19. How could Theory of Mind contribute to the differentiation of social adjustment profiles of children with externalizing behavior disorders and children with intellectual disabilities?

    Science.gov (United States)

    Nader-Grosbois, Nathalie; Houssa, Marine; Mazzone, Stéphanie

    2013-09-01

    This study compared Theory of Mind (ToM) emotion and belief abilities in 43 children with externalized behavior (EB) disorders presenting low intelligence, 40 children with intellectual disabilities (ID) and 33 typically developing (TD) preschoolers (as a control group), matched for developmental age. The links between their ToM abilities, their level in seven self-regulation strategies as displayed in social problem-solving tasks and their social adjustment profiles (assessed by the Social Competence and Behavior Evaluation, completed by their teachers) were examined. Children with EB presented lower comprehension of causes of emotions and lower self-regulation of joint attention and of attention than children with ID and TD children. In comparison with TD children, lower social adjustment was observed in nearly all dimensions of profiles in both atypical groups. Specifically, children with EB were significantly angrier than children with ID. Although variable patterns of positive correlations were obtained in atypical groups between self-regulation strategies and ToM abilities, the most numerous positive links were obtained in the group with EB. Regression analyses showed that developmental age predicted ToM abilities and certain dimensions of social adjustment profiles in atypical groups. In the ID group, ToM emotions predicted general adaptation, affective adaptation, interactions with peers and with adults and low internalizing problems. In the EB group, general adaptation was predicted by ToM emotions and self-regulation, interactions with peers by ToM beliefs, and a low level of externalizing problems by ToM emotions. Some implications for intervention and perspectives for research are suggested. Copyright © 2013 Elsevier Ltd. All rights reserved.

  20. Executive and attentional contributions to Theory of Mind deficit in attention deficit/hyperactivity disorder (ADHD).

    Science.gov (United States)

    Mary, Alison; Slama, Hichem; Mousty, Philippe; Massat, Isabelle; Capiau, Tatiana; Drabs, Virginie; Peigneux, Philippe

    2016-01-01

    Attention deficit/hyperactivity disorder (ADHD) in children has been associated with attentional and executive problems, but also with socioemotional difficulties possibly associated with deficits in Theory of Mind (ToM). Socioemotional problems in ADHD are associated with more negative prognoses, notably interpersonal, educational problems, and an increased risk of developing other psychiatric disorders that emphasize the need to clarify the nature of their ToM deficits. In this study, we hypothesized that ToM dysfunction in children with ADHD is largely attributable to their attentional and/or executive deficits. Thirty-one children with ADHD (8-12 years, IQ > 85) and 31 typically developing (TD) children were assessed using executive functions (inhibition, planning, and flexibility) and attentional tasks, as well as two advanced ToM tasks (Reading the Mind in the Eyes and Faux Pas) involving different levels of executive control. Children with ADHD performed more poorly than TD children in attentional, executive function, and ToM tasks. Linear regression analyses conducted in the ADHD group indicated that inhibition scores predicted performance on the "Faux Pas" task the best, while attention scores were the best for predicting performance on the Reading the Mind in the Eyes task. When controlled for inhibition and attentional variables, ToM performance in children with ADHD was actually similar to TD children. Contrarily, controlling for ToM scores did not normalize performance for inhibition and attentional tasks in children with ADHD. This unidirectional relationship suggests that deficits in the EF and attentional domains are responsible for ToM deficits in ADHD, which therefore may contribute to their socioemotional difficulties.