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Sample records for hee rdiger valk

  1. Heinz Valk kutsub hõiskama meie võitude üle / Heinz Valk ; interv. Toomas Sildam

    Index Scriptorium Estoniae

    Valk, Heinz, 1936-

    2006-01-01

    Balti keti üks organiseerijatest, Rahvarinde eestseisusesse kuulunud Heinz Valk vastab 70. sünnipäeva eel küsimustele, mis puudutavad perestroikat, Eesti Vabariigi taastamist, inimeste ja mineviku lepitamise võimalikkust ning tema perekonda. Lisa: Heinz Valk. Kommenteerib võitluskaaslane Rein Veidemann

  2. Heinz Valk kutsub hõiskama meie võitude üle / Heinz Valk ; interv. Toomas Sildam

    Index Scriptorium Estoniae

    Valk, Heinz, 1936-

    2006-01-01

    Balti keti üks organiseerijatest, Rahvarinde eestseisusesse kuulunud Heinz Valk vastab 70. sünnipäeva eel küsimustele, mis puudutavad perestroikat, Eesti Vabariigi taastamist, inimeste ja mineviku lepitamise võimalikkust ning tema perekonda. Lisa: Heinz Valk. Kommenteerib võitluskaaslane Rein Veidemann

  3. Heinz Valk : 20 aastat tagasi oli rohkem inimesi valmis Eesti eest surema kui täna / Heinz Valk ; interv.Urmo Soonvald

    Index Scriptorium Estoniae

    Valk, Heinz, 1936-

    2007-01-01

    President Toomas Hendrik Ilveselt Eesti iseseisvuse taastamise eest mälestuskivi pälvinud kunstnik KGB-st ja KGB kaastöötajate nimede avalikustamisest, Rahvarinde ja Eesti Komitee rivaalitsemisest ning erinevustest, poliitikast lahkumisest, presidendi tunnustusest, lause "Ükskord me võidame niikuinii" sünnist, Eestist ja eestlastest praegu ning 1988. aastal. Lisad: Valk: kui aega, kirjutan raamatu; Kes on Heinz Valk?

  4. Heinz Valk : 20 aastat tagasi oli rohkem inimesi valmis Eesti eest surema kui täna / Heinz Valk ; interv.Urmo Soonvald

    Index Scriptorium Estoniae

    Valk, Heinz, 1936-

    2007-01-01

    President Toomas Hendrik Ilveselt Eesti iseseisvuse taastamise eest mälestuskivi pälvinud kunstnik KGB-st ja KGB kaastöötajate nimede avalikustamisest, Rahvarinde ja Eesti Komitee rivaalitsemisest ning erinevustest, poliitikast lahkumisest, presidendi tunnustusest, lause "Ükskord me võidame niikuinii" sünnist, Eestist ja eestlastest praegu ning 1988. aastal. Lisad: Valk: kui aega, kirjutan raamatu; Kes on Heinz Valk?

  5. Lasva veetorn-galerii = Lasva water tower-gallery / Veronika Valk

    Index Scriptorium Estoniae

    Valk, Veronika, 1976-

    2010-01-01

    Lasva veetorni rekonstrueerimisest klavertrepiga kunstigaleriiks-vaatetorniks. Projekteerija: Zizi & Yoyo. Autorid: arhitekt Veronika Valk, arhitekti abiline Kadri Klementi, kunstnik Peeter Laurits, skulptor Kalle-Priit Pruuden, Kalle Tikas (heli elektroonika). Projekt: 2006-2008, valmis: 2009

  6. Lasva veetorn-galerii = Lasva water tower-gallery / Veronika Valk

    Index Scriptorium Estoniae

    Valk, Veronika, 1976-

    2010-01-01

    Lasva veetorni rekonstrueerimisest klavertrepiga kunstigaleriiks-vaatetorniks. Projekteerija: Zizi & Yoyo. Autorid: arhitekt Veronika Valk, arhitekti abiline Kadri Klementi, kunstnik Peeter Laurits, skulptor Kalle-Priit Pruuden, Kalle Tikas (heli elektroonika). Projekt: 2006-2008, valmis: 2009

  7. Muljeid ja mõtteid kristliku kasvatuse suurfoorumilt / Pille Valk

    Index Scriptorium Estoniae

    Valk, Pille, 1959-2009

    2001-01-01

    7.-13.05.2001 toimus Itaalias Santa Severas järjekordne Euroopa Kristliku Kasvatuse Konverents - ECCE 2001. ECCE on Euroopa suurim kristliku kasvatuse temaatikale pühendatud oikumeeniline foorum. Eestit esindasid pedagoogikamagistrid Lii Lilleoja ja Einike Pilli ning religioonipedagoogika doktorant Pille Valk. Osavõtjaid oli 19 riigist. Konverentsi üldteema oli "Läbi lapse silmade", mida lahati kolmest vaatenurgast : lapse spiritualiteet ning selle eripära ja areng, lapsed perekonnas ja ühiskonnas, lapsed Jeesuse silme läbi. Loengutest ning rühmatöödest. Konverentsi peaesineja oli dr David Hay, Oxfordi ülikooli zooloogia professor ja Usulise Kogemuse Uurimiskeskuse direktor, kes on juhtinud Nottinghami ülikooli juures lapse spiritualiteedi uurimise projekti

  8. How health economic evaluation (HEE) contributes to decision-making in public health care: the case of Brazil.

    Science.gov (United States)

    Elias, Flávia Tavares Silva; Araújo, Denizar Vianna

    2014-01-01

    The universal access to a health care system for the Brazilian population was established in 1990. Brazil is a country with no tradition in the production and use of health economic evaluation (HEE) to guide decision making in the public health system. It is only within the last two decades that HEEs using a microeconomic approach have appeared in the academic field. On a national level, HEE and Health Technology Assessment (HTA), in a wider sense, were first taken into account in 2003. Two policies deserve to be mentioned - (i) the regulation of medicines in the Brazilian market, and (ii) science, technology and innovation policy. The latter required the fostering of applied research to encourage the application of methods which employ systematic reviews and economic analyses of cost-effectiveness to guide the incorporation of technologies in the Brazilian health care system. The Ministry of Health has initiated the process of incorporating these new technologies on a federal level during the last ten years. In spite of the improvement of HEE methods at Brazilian universities and research institutes, these technologies have not yet reached the governmental bodies. In Brazil, the main challenge lies in the production, interpretation and application of HEE to all technologies within the access scheme(s), and there is limited capacity building. Setting priorities can be the solution for Brazil to be able to perform HEE for relevant technologies within the access scheme(s) while the universal coverage system struggles with a triple burden of disease. Copyright © 2014. Published by Elsevier GmbH.

  9. Pärnu maantee äärde kerkib vaikuse oaas kunstiõppureile / Mari Peegel ; kommenteerib Veronika Valk

    Index Scriptorium Estoniae

    Peegel, Mari, 1978-

    2011-01-01

    Tallinna Muusikakeskkooli, Georg Otsa nimelise Tallinna Muusikakooli ja Tallinna Balletikooli ühishoone arhitektuurikonkursi võitis Austria firma Atelier Thomas Pucher ZT GmbH töö "Vaikuse aed". Kommenteerib žürii liige Veronika Valk

  10. Physical functioning and life style of 50-65 years’ age hee teachers

    Directory of Open Access Journals (Sweden)

    Baskevich O.V.

    2015-12-01

    Full Text Available Purpose: to study life style of 50-65 years’ age university teachers depending on their physical functioning and its connection with behavior habits. Material: questioning of 150 respondents was fulfilled by specially prepared questionnaire. Anthropometric testing was conducted. Results: it was found that most of the questioned spend time watching TV or reading and pay very little attention to physical functioning. We also found that most of respondents deal with household chores but want to do something outdoors (practice public activity. There is a trend to avoid smoking among them. Only 5.0% are cigarette smokers. The rest have never smoked or gave up smoking more than 10 years ago. Among the partners of the questioned there are a lot of smokers (16.2%. Most of the questioned have friends and relatives, who can help to achieve the highest level of physical functioning. 18.9% of partners of the questioned regularly practice sports. Some useful for health habits are observed in life situations of all respondents. Conclusions: the received data witness about purposefulness of seeking of effective ways of pre retirement age HEE teachers’ involvement in active recreational functioning. We have also found that there are time reserves for this purpose.

  11. Influence of study in hee on ubiquity and strength of students’ computer gambling

    Directory of Open Access Journals (Sweden)

    Kudryavtsev M.D.

    2016-06-01

    Full Text Available Purpose: to clear up effectiveness of learning-education process for counteraction of students’ harmful passion to computer games’ ubiquity. Material: 1st - 3rd year students (main health group were the objects of the research. In total they were 952 boys and 523 girls. In 1st year students’ academic groups testing was carried out ant the beginning of academic year (October; in academic groups of 1st-3rd year students the testing was at the end of academic year (May. Results: it was found that among 1st year boy students ubiquity of computer gaming as well as time losses, connected with it are higher than among girl students. Educational process is not sufficiently effective in struggle against computer gaming. For girls, this passion is not dangerous in general. In the course of study at HEE, the strength of this passion reduces independent on sex. Conclusions: for increase of educational process’s effectiveness and improvement of students’ life quality it is necessary to consider personal features of boy students as well as to organize health related measures with the help of health related physical culture means.

  12. Two new records of palm species for Gabon: Sclerosperma profizianum Valk. & Sunder. and Eremospatha quiquecostulata Becc.

    Science.gov (United States)

    Bourobou Bourobou, Paul Henri; Niangadouma, Raoul; Issembe, Yves

    2016-01-01

    Abstract Background Gabon is an important center of biodiversity in Central Africa. The country contains to date 27 species of palms. However, palms are generally poorly collected as these massive plants are hard to press and curate. Thus, our understanding remains incomplete, especially in Central Africa. New information We report three new records of two palm species for Gabon: Sclerosperma profizianum Valk. & Sunder. and Eremospatha quiquecostulata Becc.. The former species was collected in southeast Gabon, near Ndindi, while the later was collected in the Massif du Chaillu and Monts de Cristal National Park (Crystal Mountains National Park). The total number of palm species for Gabon is now 29, making it an important centre of palm diversity in Central Africa. PMID:27956852

  13. Nicholas Cook "Pärnu nüüdismuusika päevadel 2005" / Maris Valk-Falk ; interv. Andrus Kallastu

    Index Scriptorium Estoniae

    Valk-Falk, Maris, 1934-2016

    2005-01-01

    A. Kallastu ja M. Valk-Falk muusikasotsioloogist Nicholas Cookist ja tema vaadetest muusikaanalüüsile. Kirjastuselt Scripta Musicalia ilmunud Nicholas Cooki tõlkeraamatust "Music, Imigination and Culture", raamatu esitlusest 19.-23. jaanuarini toimuvatel Pärnu nüüdismuusikapäevadel

  14. Muusikamaailm : Festivalid Cincinnatis, Viinis... . Iisrael "Valküüri" vastu. Händeli "Gloria" plaadistatud. Stockholmi Kontserdimaja suletud. Gennadi Rozhdestvenski 70 / Priit Kuusk

    Index Scriptorium Estoniae

    Kuusk, Priit, 1938-

    2001-01-01

    Muusikafestivalidest : Cincinnati maifestivalist, Viini pidunädalatest ja Schwetzingeni festivalist. Iisraeli festivali korraldajad on vastu Wagneri "Valküüride" I vaatuse kontsertettekandele juulis 2001 Jeruusalemmas. Hiljuti Londonist leitud Händeli senitundmatu käsikirjaline teos "Gloria" on plaadistatud firma BIS poolt. Stockholmi Konserthuset suleti suveks saali ümberehituse tõttu. Lühidalt G. Rozdestvenskist

  15. Muusikamaailm : Festivalid Cincinnatis, Viinis... . Iisrael "Valküüri" vastu. Händeli "Gloria" plaadistatud. Stockholmi Kontserdimaja suletud. Gennadi Rozhdestvenski 70 / Priit Kuusk

    Index Scriptorium Estoniae

    Kuusk, Priit, 1938-

    2001-01-01

    Muusikafestivalidest : Cincinnati maifestivalist, Viini pidunädalatest ja Schwetzingeni festivalist. Iisraeli festivali korraldajad on vastu Wagneri "Valküüride" I vaatuse kontsertettekandele juulis 2001 Jeruusalemmas. Hiljuti Londonist leitud Händeli senitundmatu käsikirjaline teos "Gloria" on plaadistatud firma BIS poolt. Stockholmi Konserthuset suleti suveks saali ümberehituse tõttu. Lühidalt G. Rozdestvenskist

  16. Nicholas Cook "Pärnu nüüdismuusika päevadel 2005" / Maris Valk-Falk ; interv. Andrus Kallastu

    Index Scriptorium Estoniae

    Valk-Falk, Maris, 1934-2016

    2005-01-01

    A. Kallastu ja M. Valk-Falk muusikasotsioloogist Nicholas Cookist ja tema vaadetest muusikaanalüüsile. Kirjastuselt Scripta Musicalia ilmunud Nicholas Cooki tõlkeraamatust "Music, Imigination and Culture", raamatu esitlusest 19.-23. jaanuarini toimuvatel Pärnu nüüdismuusikapäevadel

  17. Kõrghariduse kvaliteeti ei määra ainult pingerida : [Arutlevad Tartu Ülikooli õppeprorektor Birute Klaas ja Tartu Ülikoli avatud ülikooli keskuse juhataja Aune Valk] / Raivo V Raam

    Index Scriptorium Estoniae

    Raam, Raivo V

    2006-01-01

    Birute Klaas ja Aune Valk Tartu Ülikoolist käisid Coimbra grupi, mille liige Tartu Ülikool on aastast 2003, aastakoosolekul, mille raames arutleti ülikoolide rahvusvahelise pingerea temaatika üle ja selgitavad kriteeeriume, mille järgi ülikoole pingeritta seatakse

  18. Analysis of parasitic diseases diagnosed by tissue biopsy specimens at KyungHee Medical Center (1984-2005) in Seoul, Korea.

    Science.gov (United States)

    Choi, Won-Hyung; Chu, Jong-Phil; Jiang, Meihua; Lee, Yun-Sik; Kim, Bum-Shik; Kim, Deog-Gon; Park, Yong-Koo

    2010-03-01

    We analyzed parasitic diseases diagnosed by tissue biopsy specimens at KyungHee Medical Center (KMC) from 1984 to 2005. The total number of parasite infection cases was 150 (0.07%) out of the total 211,859 biopsy specimens submitted for histopathological examinations. They consisted of 62 cysticercosis, 23 sparganosis, 16 paragonimiasis, 15 amebiasis, 11 anisakiasis, 11 clonorchiasis, 3 ascariasis, 2 scabies, 2 enterobiasis, 2 trichuriasis, 1 leishmaniasis, 1 taeniasis, and 1 thelaziasis. Out of 62 cysticercosis cases, 55 were detected in subcutaneous tissues or the central nerve system. Eighteen out of 23 sparganosis cases were involved in muscular and subcutaneous tissues. In most anisakiasis cases, the involved organ was the stomach. The lung and the pleura were the most common site of paragonimiasis. The incidence of parasitic diseases during the first 5 years (1984-1988) was the highest of all observed periods. After 1989, similar incidences were shown throughout the period. Whereas cysticercosis was diagnosed in 34 cases during 1984-1988, no case has been diagnosed since 2000. In the case of sparganosis, the chronological incidence was almost uniform throughout the period 1984-2005. Paragonimiasis showed a similar tendency to cysticercosis. In gender and age distribution of parasitic diseases, men showed higher incidence rates than females, and the age groups of the 40s or older indicated higher infection frequencies than other age groups. Therefore, these results are a significant report to appear the tendency of human parasitic disease diagnosed by tissue biopsy in association with parasitosis at KMC in Seoul.

  19. Kumu täidavad rahvuslikud sümbolid, rasked valikud ja elav haridustöö / Marika Valk, Tiina Abel, Eha Komissarov...[jt.] ; interv. Ave Randviir

    Index Scriptorium Estoniae

    2006-01-01

    Eesti Kunstimuuseumi direktor Marika Valk, Kumu hariduskeskuse kunstnik-metoodik Anu Purre, Kumu kuraatorid Tiina Abel (püsiväljapanek Eesti kunsti klassikast ) ja Eha Komissarov (püsiväljapanek Eesti kunstist Teise Maailmasõja lõpust taasiseseisvumiseni) ning Kumu auditooriumi programmijuht-kuraator Maria-Kristiina Soomre uue muuseumi rollist, väljapanekutest, haridusprogrammidest. Lõpus "Pärle Kumu kuraatorite valikul"

  20. An integrated hydrological, ecological, and economical (HEE) modeling system for assessing water resources and ecosystem production: calibration and validation in the upper and middle parts of the Yellow River Basin, China

    Science.gov (United States)

    Li, Xianglian; Yang, Xiusheng; Gao, Wei

    2006-08-01

    Effective management of water resources in arid and semi-arid areas demands studies that cross over the disciplinaries of natural and social sciences. An integrated Hydrological, Ecological and Economical (HEE) modeling system at regional scale has been developed to assess water resources use and ecosystem production in arid and semi-arid areas. As a physically-based distributed modeling system, the HEE modeling system requires various input parameters including those for soil, vegetation, topography, groundwater, and water and agricultural management at different spatial levels. A successful implementation of the modeling system highly depends on how well it is calibrated. This paper presented an automatic calibration procedure for the HEE modeling system and its test in the upper and middle parts of the Yellow River basin. Previous to calibration, comprehensive literature investigation and sensitivity analysis were performed to identify important parameters for calibration. The automatic calibration procedure was base on conventional Monte Carlo sampling method together with a multi-objective criterion for calibration over multi-site and multi-output. The multi-objective function consisted of optimizing statistics of mean absolute relative error (MARE), Nash-Sutcliffe model efficiency coefficient (E NS), and coefficient of determination (R2). The modeling system was calibrated against streamflow and harvest yield data from multiple sites/provinces within the basin over 2001 by using the proposed automatic procedure, and validated over 1993-1995. Over the calibration period, the mean absolute relative error of simulated daily streamflow was within 7% while the statistics R2 and E NS of daily streamflow were 0.61 and 0.49 respectively. Average simulated harvest yield over the calibration period was about 9.2% less than that of observations. Overall calibration results have indicated that the calibration procedures developed in this study can efficiently calibrate

  1. Ethos homoafetivo e constructos retórico-discursivos no romance brasileiro contemporâneo: uma análise das obras “Trem fantasma”, de Carlos Hee, e “Cinema Orly, de Luis Capucho

    Directory of Open Access Journals (Sweden)

    Thiago Ianez Carbonel

    2013-08-01

    Full Text Available Este estudo objetiva demonstrar como constructos retórico-discursivos podem evidenciar a existência de uma produção homoerótica que caracteriza a realidade de uma literatura gay na produção cultural brasileira. Nosso foco são Trem fantasma, de Carlos Hee, e Cinema Orly, de Luis Capucho, porque nossa finalidade é demonstrar como há uma tendência atual de autores gays escreverem obras literárias de temática gay, e isso não está relacionado apenas a autores mais consagrados, como Caio Fernando Abreu e outros. Na verdade, nós tentamos demonstrar que essa tendência segue diferentes caminhos de acordo com as características pessoais de cada autor.

  2. Keskendumine elukestvale õppele / Aune Valk

    Index Scriptorium Estoniae

    Valk, Aune, 1972-

    Elukestev õpe on Euroopa Kõrgharidusruumi olemuslik osa. Teadmistepõhisel ühiskonnal ja majandusel rajanevas tuleviku-Euroopas on elukestva õppe strateegiad vajalikud selleks, et seista vastu võistluslikkuse ja uute tehnoloogiate poolt esitatud väljakutsetele ning parandada sotsiaalset sidusust, võrdseid võimalusi ja elukvaliteeti

  3. Kiriku ülestõstmisest / Veronika Valk

    Index Scriptorium Estoniae

    Valk, Veronika, 1976-

    2011-01-01

    Kiriku korrastamiseks ja tööshoidmiseks napib tihti raha. Eesti luteri kogudused vajavad abi. Uutest kirikukelladest Eestis, kellamängudest. Näiteid nüüdiskunstist mahajäetud kirikutes. Melbourne´i festivali raames 2010. a. näitas Bill Viola oma videokunsti Parkville´i St. Carthage´i katoliku kirikus. Londonis 2006. a. Michael Crossi kirikusse loodud teosest "Bridge". Briti kunstnike Heather Ackroydi ja Dan Harvey poolt Dilston Grove'i kirikusse Londonis 2003. a. loodud vertikaalse murukasvatuse projektist

  4. 20 aastat tagasi ja edasi / Heinz Valk

    Index Scriptorium Estoniae

    Valk, Heinz, 1936-

    2008-01-01

    Heites pilgu 20 aasta taha, ütleb autor, et vabaduse poole edasiliikumise edukuse taga oli võimas ühtsustunne ning kogu rahva hingejõu ja tegutsemistahte kontsentratsioon. 1988. aastaga võrreldes mõjutas kõige ebameeldivamalt Eesti ühiskonda kõrgete aadete kiire mõranemine kitsa kambavaimu võimuiha ees

  5. 20 aastat tagasi ja edasi / Heinz Valk

    Index Scriptorium Estoniae

    Valk, Heinz, 1936-

    2008-01-01

    Heites pilgu 20 aasta taha, ütleb autor, et vabaduse poole edasiliikumise edukuse taga oli võimas ühtsustunne ning kogu rahva hingejõu ja tegutsemistahte kontsentratsioon. 1988. aastaga võrreldes mõjutas kõige ebameeldivamalt Eesti ühiskonda kõrgete aadete kiire mõranemine kitsa kambavaimu võimuiha ees

  6. Eesti riik edutagu vene eliiti / Heinz Valk

    Index Scriptorium Estoniae

    Valk, Heinz, 1936-

    2008-01-01

    Ilmunud ka: Molodjozh Estonii 28. apr. lk. 5. Autor on seisukohal, et vene liidreid peaksid edutama kõik erakonnad, avalikus teenistuses peaks olema rohkem vene päritolu spetsialiste. Integratsiooni toimimiseks on riigil vaja partnerit, selleks saab olla siinne vene eliit

  7. Que pasa? Mis toimub? / Veronika Valk

    Index Scriptorium Estoniae

    Valk, Veronika, 1976-

    2005-01-01

    Ettepanek luua Tallinna sadama infopunkt endisesse politseimajja Admiraliteedi basseini ääres. I korrusel paikneks infosaal, II ja III korruse võiks kunstnikele, musikutele jne. välja rentida, nende kõrvale mahuksid galeriid. Tänase Tallinna moto ning mereäärse ala planeerimise kontseptsioon võiksa olla "mereõhk teeb vabaks"

  8. Que pasa? Mis toimub? / Veronika Valk

    Index Scriptorium Estoniae

    Valk, Veronika, 1976-

    2005-01-01

    Ettepanek luua Tallinna sadama infopunkt endisesse politseimajja Admiraliteedi basseini ääres. I korrusel paikneks infosaal, II ja III korruse võiks kunstnikele, musikutele jne. välja rentida, nende kõrvale mahuksid galeriid. Tänase Tallinna moto ning mereäärse ala planeerimise kontseptsioon võiksa olla "mereõhk teeb vabaks"

  9. Kiriku ülestõstmisest / Veronika Valk

    Index Scriptorium Estoniae

    Valk, Veronika, 1976-

    2011-01-01

    Kiriku korrastamiseks ja tööshoidmiseks napib tihti raha. Eesti luteri kogudused vajavad abi. Uutest kirikukelladest Eestis, kellamängudest. Näiteid nüüdiskunstist mahajäetud kirikutes. Melbourne´i festivali raames 2010. a. näitas Bill Viola oma videokunsti Parkville´i St. Carthage´i katoliku kirikus. Londonis 2006. a. Michael Crossi kirikusse loodud teosest "Bridge". Briti kunstnike Heather Ackroydi ja Dan Harvey poolt Dilston Grove'i kirikusse Londonis 2003. a. loodud vertikaalse murukasvatuse projektist

  10. Adele Reindorff - 100 / Endel Valk-Falk

    Index Scriptorium Estoniae

    Valk-Falk, Endel, 1932-

    2001-01-01

    36 aastat nahkehistöö kateedrit juhatanud Adele Reindorffist, tema loomingust, õpilasi. Eriala rajamisest Riigi Kunsttööstuskoolis. A. Reindorffi 100. sünniaastapäevale pühendatud eesti köidete näituskonkursi tööd on väljas EAR-is.

  11. Gothic bindings and their restoration / Endel Valk-Falk

    Index Scriptorium Estoniae

    Valk-Falk, Endel, 1932-

    2008-01-01

    Gooti stiilist köitekunstis, kahjustustest keskaegsetel köidetel ja nende restaureemisest TA Raamatukogus. Ettekannete teesid konverentsilt ICOM Committee for Conservation 5th Triennial Meeting, Zagreb, 1978

  12. Gothic bindings and their restoration / Endel Valk-Falk

    Index Scriptorium Estoniae

    Valk-Falk, Endel, 1932-

    2008-01-01

    Gooti stiilist köitekunstis, kahjustustest keskaegsetel köidetel ja nende restaureemisest TA Raamatukogus. Ettekannete teesid konverentsilt ICOM Committee for Conservation 5th Triennial Meeting, Zagreb, 1978

  13. Tere tulemast tagasi, uue põlvkonna utopistid! / Veronika Valk

    Index Scriptorium Estoniae

    Valk, Veronika, 1976-

    2011-01-01

    Francois Roche ja Eva Castro tulevikuarhitektuuri käsitlevatest ettekannetest Tallinna arhitektuuribiennaali raames toimunud sümpoosionil. Maketinäitus "Viini eksiilid. Helisev arhitektuur" Heliose kinos. Eksponeeritakse Viini Die Angewandte arhitektuurikoolis (juht Hani Rashid) õppivate eestlaste loomingut

  14. Sisse- ja väljajuhatuseks / Aune Valk

    Index Scriptorium Estoniae

    Valk, Aune

    2008-01-01

    LÜKKA projekti raames 2005-2007 peamiselt avalik-õiguslikes ülikoolides läbi viidud uuringutest, mille eesmärk oli saada ülevaade olulisematest kitsaskohtadest Eesti kõrghariduses. LÜKKA alaprojektid käsitlesid järgmisi teemasid : kvaliteet, õppekavad, õpetamine, nõustamine, praktika, VÕTA ja õpingute katkestmine, üliõpilaste sotsiaal-majanduslik toimetulek. LÜKKA projekti uuringutes osales ka Tallinna Ülikool

  15. Muljeid ja mõtteid kristliku kasvatuse suurfoorumilt / Pille Valk

    Index Scriptorium Estoniae

    Valk, Pille, 1959-2009

    2001-01-01

    7.-13.05.2001 toimus Itaalias Euroopa Kristliku Kasvatuse Konverents, mille üldteema oli "Läbi lapse silmade". Seda lahati kolmest vaatenurgast: lapse spiritualiteet ning selle eripära ja areng, lapsed perekonnas ja ühiskonnas, lapsed Jeesuse silme läbi. Loengutest ning rühmatöödest. Konverentsi peaesineja oli dr. David Hay, Oxfordi ülikooli zooloogia professor ja Usulise Kogemuse Uurimiskeskuse direktor

  16. Vene piirist ja piirikaitsest Eesti kagunurgas keskajal / Heiki Valk

    Index Scriptorium Estoniae

    Valk, Heiki, 1959-

    2006-01-01

    Piiri olemasolu mõjust piirialade elanike elukorraldusele ja sotsiaalsele staatusele, piiriala kontrollimiseks vajalikust infrastruktuurist, piirikaitsekorraldusest ning Siksälä kalme relvahaudadest

  17. Ristikultuuri äratajad / Heinz Valk, Eerik Kõuts, Sirje Endre

    Index Scriptorium Estoniae

    Valk, Heinz, 1936-

    1998-01-01

    Intervjuu raamatu "Rist ja raud" autorite Heinz Valgu ja Eerik Kõutsiga meie kalmistukultuurist ja vanadest sepistest ning raamatu väljaandja Sirje Endrega; raamatu fotode autor on Tiit Veermäe, kujundaja Andres Tali

  18. Ristikultuuri äratajad / Heinz Valk, Eerik Kõuts, Sirje Endre

    Index Scriptorium Estoniae

    Valk, Heinz, 1936-

    1998-01-01

    Intervjuu raamatu "Rist ja raud" autorite Heinz Valgu ja Eerik Kõutsiga meie kalmistukultuurist ja vanadest sepistest ning raamatu väljaandja Sirje Endrega; raamatu fotode autor on Tiit Veermäe, kujundaja Andres Tali

  19. Kosmosekostüümid ulmefilmides / Helen Valk

    Index Scriptorium Estoniae

    Valk, Helen

    2011-01-01

    Lõputöös uuritakse ulmefilmide kostüümides esinevaid korrapärasusi ja reegleid ning seoseid reaalsuse ja ulme vahel, samuti ulme ilminguid tänapäeva moes. Praktilise tööna valmis prêt-á-porter moekollektsioon "Nebula"

  20. Vene piirist ja piirikaitsest Eesti kagunurgas keskajal / Heiki Valk

    Index Scriptorium Estoniae

    Valk, Heiki, 1959-

    2006-01-01

    Piiri olemasolu mõjust piirialade elanike elukorraldusele ja sotsiaalsele staatusele, piiriala kontrollimiseks vajalikust infrastruktuurist, piirikaitsekorraldusest ning Siksälä kalme relvahaudadest

  1. Tere tulemast tagasi, uue põlvkonna utopistid! / Veronika Valk

    Index Scriptorium Estoniae

    Valk, Veronika, 1976-

    2011-01-01

    Francois Roche ja Eva Castro tulevikuarhitektuuri käsitlevatest ettekannetest Tallinna arhitektuuribiennaali raames toimunud sümpoosionil. Maketinäitus "Viini eksiilid. Helisev arhitektuur" Heliose kinos. Eksponeeritakse Viini Die Angewandte arhitektuurikoolis (juht Hani Rashid) õppivate eestlaste loomingut

  2. Avastusi makulatuurkaantes ja kaante vahel / Endel Valk-Falk

    Index Scriptorium Estoniae

    Valk-Falk, Endel, 1932-

    2008-01-01

    Senitundmatust Tallinna katekismusest 1649. aastast, mis leiti raamatu "Polydori Vergilii Urbinatis Anglicae Historiae" köite kaante vahelt. Viimase lehtede ehisraami ja dekoratiivraamistuses initsiaalide väidetavaks autoriks on Hans Holbein noorem

  3. Euroopa vajab disainitud koostööd / Veronika Valk

    Index Scriptorium Estoniae

    Valk, Veronika, 1976-

    2004-01-01

    Hollandi arhitektuurikriitikud kutsusid ühise manifesto loomiseks Rotterdamis kokku 25 Euroopa riigi noored arhitektid. Eestist olid esindatud KavaKava, Kosmos ja 3+1 arhitektid. Ühendusest Young European Architects (YEA) ja väikeste arhitektuuribüroode koostööst Euroopa Liidus

  4. Introduction : [artiklikogumikule Ecumenical theological education] / Anne Kull, Pille Valk

    Index Scriptorium Estoniae

    Kull, Anne, 1959-

    2009-01-01

    Sissejuhatus kogumikule, mis sisaldab artikleid Tartu Ülikoolis 11.-14. jaan. 2007 toimunud konverentsi "Ecumenical theological education : pedagogical perspectives and practical experiences" ettekannetest

  5. Muljeid ja mõtteid kristliku kasvatuse suurfoorumilt / Pille Valk

    Index Scriptorium Estoniae

    Valk, Pille, 1959-2009

    2001-01-01

    7.-13.05.2001 toimus Itaalias Euroopa Kristliku Kasvatuse Konverents, mille üldteema oli "Läbi lapse silmade". Seda lahati kolmest vaatenurgast : lapse spiritualiteet ning selle eripära ja areng, lapsed perekonnas ja ühiskonnas, lapsed Jeesuse silme läbi. Loengutest ning rühmatöödest. Konverentsi peaesineja oli dr. David Hay, Oxfordi ülikooli zooloogia professor ja Usulise Kogemuse Uurimiskeskuse direktor, kes on juhtinud Nottinghami ülikooli juures lapse spiritualiteedi uurimise projekti

  6. Kosmosekostüümid ulmefilmides / Helen Valk

    Index Scriptorium Estoniae

    Valk, Helen

    2011-01-01

    Lõputöös uuritakse ulmefilmide kostüümides esinevaid korrapärasusi ja reegleid ning seoseid reaalsuse ja ulme vahel, samuti ulme ilminguid tänapäeva moes. Praktilise tööna valmis prêt-á-porter moekollektsioon "Nebula"

  7. Euroopa dimensioonide edendamine kõrghariduses / Aune Valk

    Index Scriptorium Estoniae

    Valk, Aune, 1972-

    Bologna deklaratsioonis on Euroopa dimensioonide arendamine üks kuuest eesmärgist. Euroopa dimensioonidena nimetatakse muuhulgas ka õppekavaarendust, kõrgkoolidevahelist koostööd, mobiilsusskeeme ning haridus-, koolitus-, ja teadusprogramme, kuid see ilmneb ka kvaliteedi tagamises ja nõustamises

  8. Health economics education in undergraduate medical training: introducing the health economics education (HEe) website.

    Science.gov (United States)

    Oppong, Raymond; Mistry, Hema; Frew, Emma

    2013-09-13

    In the UK, the General Medical Council clearly stipulates that upon completion of training, medical students should be able to discuss the principles underlying the development of health and health service policy, including issues relating to health economics. In response, researchers from the UK and other countries have called for a need to incorporate health economics training into the undergraduate medical curricula. The Health Economics education website was developed to encourage and support teaching and learning in health economics for medical students. It was designed to function both as a forum for teachers of health economics to communicate and to share resources and also to provide instantaneous access to supporting literature and teaching materials on health economics. The website provides a range of free online material that can be used by both health economists and non-health economists to teach the basic principles of the discipline. The Health Economics education website is the only online education resource that exists for teaching health economics to medical undergraduate students and it provides teachers of health economics with a range of comprehensive basic and advanced teaching materials that are freely available. This article presents the website as a tool to encourage the incorporation of health economics training into the undergraduate medical curricula.

  9. Health economics education in undergraduate medical training: introducing the health economics education (HEe) website

    OpenAIRE

    Oppong, Raymond; Mistry, Hema; Frew, Emma

    2013-01-01

    In the UK, the General Medical Council clearly stipulates that upon completion of training, medical students should be able to discuss the principles underlying the development of health and health service policy, including issues relating to health economics. In response, researchers from the UK and other countries have called for a need to incorporate health economics training into the undergraduate medical curricula. The Health Economics education website was developed to encourage and sup...

  10. Results of experimental testing of hee girl students’ motor skills at aerobic trainings

    Directory of Open Access Journals (Sweden)

    Martinova N. P.

    2015-10-01

    Full Text Available Purpose: to analyze dynamic of motor skills’ formation in girl students, who practice aerobic by experimental program. Material: in the research 40 girl students participated. Motor skills level was tested with the help of state and additional tests. Results: it was found that for training quickness it is necessary to use rope skipping in mode, corresponding to development of this quality. For training maximal strength it is purposeful to use more complex power exercises in ground part of the complex. Conclusions: implementation of rope skipping means in dance aerobic trainings increases training influence on practically all motor skills. Rope skipping permits to doze and regulate training load. The same under musical accompaniment develop sense of rhythm. In some modes such jumps facilitate training of speed power qualities and power endurance.

  11. Measurement of the reaction 2H(e,e') at 180 degrees close to the deuteron breakup threshold.

    Science.gov (United States)

    Ryezayeva, N; Arenhövel, H; Burda, O; Byelikov, A; Chernykh, M; Enders, J; Griesshammer, H W; Kalmykov, Y; von Neumann-Cosel, P; Ozel, B; Poltoratska, I; Pysmenetska, I; Rangacharyulu, C; Rathi, S; Richter, A; Schrieder, G; Shevchenko, A; Yevetska, O

    2008-05-01

    Inclusive inelastic electron scattering off the deuteron under 180 degrees has been studied at the S-DALINAC close to the breakup threshold at momentum transfers q=0.27 fm;{-1} and 0.74 fm;{-1} with good energy resolution sufficient to map in detail the spin flip M1 response, which governs the starting reaction pn-->dgamma of big-bang nucleosynthesis over most of the relevant temperature region. Results from potential model calculations and (for q=0.27 fm;{-1}) from pionless nuclear effective field theory are in excellent agreement with the data.

  12. Military Authoritarian Regimes and Economic Development: The ROK’s Economic Take-Off Under Park Chung Hee

    Science.gov (United States)

    2008-12-01

    connection exists between modernization and authoritarian regimes? Talcott Parsons was the foremost advocate of social evolutionism. According to his...and the Personalization of Power in Malaysia," Comparative Politics 36, no. 1 (Oct. 2003), 81-101. 2 Talcott Parsons , Theories of Society...Foundations of Modern Sociological Theory (New York: Free Press of Glencoe, 1961). 3 Max Weber and Talcott Parsons , The Theory of Social and Economic

  13. Medieval and Post-medieval archaeology of the native rural population / Heiki Valk

    Index Scriptorium Estoniae

    Valk, Heiki, 1959-

    2006-01-01

    Kohaliku elnikkonna elu keskajal ja keskajajärgsel perioodil uuriva arheoloogia arengust Eestis. Uuringud selles valdkonnas suurenesid märgatavalt alates 1970ndate aastate lõpust. Kohaliku elanikkonna asustusest säilinud leiumaterjal erineb oluliselt baltisaksa "euroopalikest" keskustest leitust. Arheoloogilise leiumaterjali põhjal on alust rääkida selgest etno-sotsiaalsest eristumisest

  14. Rescue excavations on Alt-Laari settlement site, Tartumaa / Anti Lillak, Heiki Valk

    Index Scriptorium Estoniae

    Lillak, Anti

    2009-01-01

    Alt-Laari linnusasula tekkis nähtavasti rooma rauaajal. Kui Alt-Laari linnus oli kasutused arvatavasti I aastatuhandest II aastatuhandeni pKr. siis asula kestis edasi keskajal ning jäeti maha hiljemalt 14. sajandil

  15. Kaasaeg vajab pragmaatikuid / Alejandro Zaera-Polo ; intervjueerinud Triin Ojari, Veronika Valk, Toomas Tammis

    Index Scriptorium Estoniae

    Zaera-Polo, Alejandro

    2012-01-01

    Eesti Kunstiakadeemia arhitektuuriteaduskonna välisesinejate loengusarjas esinenud hispaania arhitekt Alejandro Zaera-Polo, kes 2012. aastast juhib Princetoni ülikooli arhitektuurikooli, räägib endast, arhitektuuriharidusest, linnaplaneerimisest, hoone väliskesta (envelope) poliitilisusest

  16. "See jälkus tuleb otsekohe lõpetada!" / Heinz Valk

    Index Scriptorium Estoniae

    Valk, Heinz, 1936-

    2011-01-01

    Artikli autor meenutab, kuidas nõukogude ajal tuli eemaldada kunstinäitustelt nõukogudevaenulikke töid. Heinz Valgu 1976. aasta isiknäitusest Tallinna Kunstihoones, Leonhard Lapini näitusest "Naine-masin" 1977. aastal, Vello Tamme isiknäitusest 1981. aastal

  17. Liam Young, soovtulevike vormija = Liam Young; shaper of preferable futures / Veronika Valk

    Index Scriptorium Estoniae

    Valk, Veronika

    2016-01-01

    Lühike ülevaade austraalia päritolu arhitekti Liam Youngi avatud loengusarja raames peetud loengust, milles ta toob välja arhitektide ja linnaplaneerijate uued ülesanded linnaruumi kujundamisel tulevikus uute tehnoloogiatega

  18. Täpne arhitektuur : ACADIA aastakonverents Cooper Unioni arhitektuurikoolis / Veronika Valk

    Index Scriptorium Estoniae

    Valk, Veronika, 1976-

    2010-01-01

    Septembris 2010 toimunud ACADIA aastakonverentsist New Yorgis. Konverents, töötoad ja näitus pakkusid parameetrilise projekteerimise spetsialistidele üle maailma lava, kus arhitektuuri uusi suundi arutada ja oma praktika üle mõtteid vahetada

  19. Medieval and Post-medieval archaeology of the native rural population / Heiki Valk

    Index Scriptorium Estoniae

    Valk, Heiki, 1959-

    2006-01-01

    Kohaliku elnikkonna elu keskajal ja keskajajärgsel perioodil uuriva arheoloogia arengust Eestis. Uuringud selles valdkonnas suurenesid märgatavalt alates 1970ndate aastate lõpust. Kohaliku elanikkonna asustusest säilinud leiumaterjal erineb oluliselt baltisaksa "euroopalikest" keskustest leitust. Arheoloogilise leiumaterjali põhjal on alust rääkida selgest etno-sotsiaalsest eristumisest

  20. Religiooniõpetus - anakronism või alahinnatud võimalus? / Pille Valk

    Index Scriptorium Estoniae

    Valk, Pille, 1959-2009

    2001-01-01

    Artiklis tutvustakse osa uurimisprojektist "Kaasaegse religiooniõpetuse kontseptsioon Eesti üldhariduskoolile". Tuginedes religiooniõpetusega tegelevate rahvusvaheliste organisatsioonide dokumentidele (Loccum Statement 1990, Common discussion paper 1997, Towards cooperation 1999) sõnastatakse religiooniõpetuse eesmärgid tänase Euroopa haridusmaastikul. Eesti religiooniõpetuse ajaloost; õpilaste, õpetajate ja koolijuhtide suhtumisi ja ootusi seoses religiooniõpetusega.

  1. Ghostly possession and real estate : the dead in contemporary Estonian folklore / Ülo Valk

    Index Scriptorium Estoniae

    Valk, Ülo, 1962-

    2006-01-01

    Vaimudest üldises, sotsiaalses ja ajaloolises kontekstis, surnute tagasipöördumisest ja nende mõjust tänapäeva inimestele. Artikkel põhineb eesti saartel tehtud intervjuudele, kus uuriti kodude mahajätmist ja sealt väljaajamist seoses nõukogude süsteemiga ning sellega seotud kummituslugusid

  2. Ghostly possession and real estate : the dead in contemporary Estonian folklore / Ülo Valk

    Index Scriptorium Estoniae

    Valk, Ülo, 1962-

    2006-01-01

    Vaimudest üldises, sotsiaalses ja ajaloolises kontekstis, surnute tagasipöördumisest ja nende mõjust tänapäeva inimestele. Artikkel põhineb eesti saartel tehtud intervjuudele, kus uuriti kodude mahajätmist ja sealt väljaajamist seoses nõukogude süsteemiga ning sellega seotud kummituslugusid

  3. Ühe legendi lõppvaatus / Ants Juske ; kommenteerinud Heinz Valk, Matti Varik

    Index Scriptorium Estoniae

    Juske, Ants, 1956-

    2009-01-01

    Arhitekt Allan Murdmaa (4. august 1934 - 15. november 2009) mälestusnäitus "Monumentaalne" Arhitektuuri- ja Disainigaleriis. Koostanud Toivo Tammik, kujundanud Martin Pedanik, fotod: Arne Maasik. Allan Murdmaa elust, loomingust ja eluloolisi andmeid

  4. New data about the besieging constructions from 1223 in Viljandi / Heiki Valk

    Index Scriptorium Estoniae

    Valk, Heiki, 1959-

    2006-01-01

    Viljandis jätkusid kaevamised Lossimägedes, kus varasemad kaevamised lubasid oletada Muinas- ja keskaja piirimaadelt pärinevat kindlustatud ülikumõisat. Oletatust kitsam mäeplatoo seab kahtluse alla hüpoteesi siseõuega muinasmõisast või linnustalust

  5. The hoard of Palutaja from the time of the Livonian War / Heiki Valk, Tõnno Jonuks

    Index Scriptorium Estoniae

    Valk, Heiki, 1959-

    2007-01-01

    Põlvamaalt (ajalooline Võrumaa, Kanepi kihelkond) Palutaja külast leitud aardest. Palutaja aare sisaldab Liivi sõja aegsetele Lõuna- ja Kesk-Eesti peitleidudele iseloomulikke esemeid. Tegemist on osaga aardest

  6. Liam Young, soovtulevike vormija = Liam Young; shaper of preferable futures / Veronika Valk

    Index Scriptorium Estoniae

    Valk, Veronika

    2016-01-01

    Lühike ülevaade austraalia päritolu arhitekti Liam Youngi avatud loengusarja raames peetud loengust, milles ta toob välja arhitektide ja linnaplaneerijate uued ülesanded linnaruumi kujundamisel tulevikus uute tehnoloogiatega

  7. Religiooniõpetus - anakronism või alahinnatud võimalus? / Pille Valk

    Index Scriptorium Estoniae

    Valk, Pille, 1959-2009

    2001-01-01

    Artiklis tutvustakse osa uurimisprojektist "Kaasaegse religiooniõpetuse kontseptsioon Eesti üldhariduskoolile". Tuginedes religiooniõpetusega tegelevate rahvusvaheliste organisatsioonide dokumentidele (Loccum Statement 1990, Common discussion paper 1997, Towards cooperation 1999) sõnastatakse religiooniõpetuse eesmärgid tänase Euroopa haridusmaastikul. Eesti religiooniõpetuse ajaloost; õpilaste, õpetajate ja koolijuhtide suhtumisi ja ootusi seoses religiooniõpetusega.

  8. "See jälkus tuleb otsekohe lõpetada!" / Heinz Valk

    Index Scriptorium Estoniae

    Valk, Heinz, 1936-

    2011-01-01

    Artikli autor meenutab, kuidas nõukogude ajal tuli eemaldada kunstinäitustelt nõukogudevaenulikke töid. Heinz Valgu 1976. aasta isiknäitusest Tallinna Kunstihoones, Leonhard Lapini näitusest "Naine-masin" 1977. aastal, Vello Tamme isiknäitusest 1981. aastal

  9. Muinasajast saksa ordu ja piiskoppide aega. Keskaeg : I aastatuhandest - XVI sajandini / Kristel Valk

    Index Scriptorium Estoniae

    Valk, Kristel

    2005-01-01

    Objektide kirjeldused - rehielamu, Valjala kirik, Narva Hermanni kindlus, Tallinna vanalinn ja Toompea, Oleviste, Püha Vaimu ja Tartu Jaani kirik, Pirita klooster, Tallinna raekoda, Suurgildi hoone ja kaupmeheelamu Tallinnas

  10. Mida täiskasvanute oskuste uuring meile näitas? / Aune Valk, Vivika Halapuu

    Index Scriptorium Estoniae

    Valk, Aune, 1972-

    2013-01-01

    Avalikustati rahvusvahelise täiskasvanute oskuste uuringu PIAAC tulemused, mis näitas meie 16-65-aastaste inimeste peamiste infotöötlusoskuste taset nii riigi sees kui ka võrdluses teiste riikidega

  11. Looduslikud pühapaigad kui muistised : arheoloogia vaatenurk / Heiki Valk

    Index Scriptorium Estoniae

    Valk, Heiki, 1959-

    2007-01-01

    Looduslikest pühapaikadest kui arheoloogiamälestistest, nende uurimisloost ja hoiakutest. Rahvaluuleteaduse huvist looduslike pühapaikade vastu. Looduslike pühapaikade pühapaiga omandamise tähendusest ajas. Pühakohtade liikidest, tähendusest ja otstarbest. Asustuslikest seostest ja kohtadest rituaalsel maastikul. Pühapaigast kui osast võrgustikust, tema tähtsusastmetest ja hierarhiast. Pühapaikade kohavaliku põhjustest. Lühidalt autorist lk. 317

  12. Meie, eurooplased üheskoos / Tiina Valk, Raine Lindepuu, Kaia Kurg

    Index Scriptorium Estoniae

    Valk, Tiina

    2006-01-01

    Sadala Põhikool käivitas äsjalõppenud õppeaastal koos ühe Prantsusmaa, ühe Šotimaa, ühe Saksamaa ja ühe Poola kooliga Comeniuse programmist rahastatava projekti "Meie, eurooplased üheskoos"

  13. Kaasaeg vajab pragmaatikuid / Alejandro Zaera-Polo ; intervjueerinud Triin Ojari, Veronika Valk, Toomas Tammis

    Index Scriptorium Estoniae

    Zaera-Polo, Alejandro

    2012-01-01

    Eesti Kunstiakadeemia arhitektuuriteaduskonna välisesinejate loengusarjas esinenud hispaania arhitekt Alejandro Zaera-Polo, kes 2012. aastast juhib Princetoni ülikooli arhitektuurikooli, räägib endast, arhitektuuriharidusest, linnaplaneerimisest, hoone väliskesta (envelope) poliitilisusest

  14. Mida täiskasvanute oskuste uuring meile näitas? / Aune Valk, Vivika Halapuu

    Index Scriptorium Estoniae

    Valk, Aune, 1972-

    2013-01-01

    Avalikustati rahvusvahelise täiskasvanute oskuste uuringu PIAAC tulemused, mis näitas meie 16-65-aastaste inimeste peamiste infotöötlusoskuste taset nii riigi sees kui ka võrdluses teiste riikidega

  15. Täpne arhitektuur : ACADIA aastakonverents Cooper Unioni arhitektuurikoolis / Veronika Valk

    Index Scriptorium Estoniae

    Valk, Veronika, 1976-

    2010-01-01

    Septembris 2010 toimunud ACADIA aastakonverentsist New Yorgis. Konverents, töötoad ja näitus pakkusid parameetrilise projekteerimise spetsialistidele üle maailma lava, kus arhitektuuri uusi suundi arutada ja oma praktika üle mõtteid vahetada

  16. Looduslikud pühapaigad kui muistised : arheoloogia vaatenurk / Heiki Valk

    Index Scriptorium Estoniae

    Valk, Heiki, 1959-

    2007-01-01

    Looduslikest pühapaikadest kui arheoloogiamälestistest, nende uurimisloost ja hoiakutest. Rahvaluuleteaduse huvist looduslike pühapaikade vastu. Looduslike pühapaikade pühapaiga omandamise tähendusest ajas. Pühakohtade liikidest, tähendusest ja otstarbest. Asustuslikest seostest ja kohtadest rituaalsel maastikul. Pühapaigast kui osast võrgustikust, tema tähtsusastmetest ja hierarhiast. Pühapaikade kohavaliku põhjustest. Lühidalt autorist lk. 317

  17. Autorsus ja tekstuaalsus : "Kalevipoeg" kui eepiline maastik / Ülo Valk ; inglise keelest tõlkinud Maili Pilt

    Index Scriptorium Estoniae

    Valk, Ülo, 1962-

    2003-01-01

    Artikli ingliskeelne versioon "Authorship and textuality: The Kalevipoeg as epic landscape" on ilmunud kogumikus "The Kalevala and the world's traditional epics" (toim. Lauri Honko). Helsinki : Finnish Literature Society, 2002.

  18. Excavations in the ruins of Vastseliina castle and on the hillforts of Urvaste and Hinniala / Heiki Valk

    Index Scriptorium Estoniae

    Valk, Heiki, 1959-

    2007-01-01

    2006. aastal jätkusid kaevamised, mille eesmärk on tuua selgust Võrumaa kronoloogia küsimusse. Kaevamistest Vastseliina linnusel, Hinniala linnamäel (ka Päevapööramise mägi), mida on pärimuses peetud ohvripaigaks. Hinniala linnamäe seotusest ümbruskonna arheoloogiliste objektidega. Kaevamistest Urvaste (Järveküla) linnamäel

  19. Lugejad küsivad - autorid vastavad : [teemad: kasumiaruandest...] / Toomas Villems, Madis Valk, Maire Otsus-Carpenter... [jt.

    Index Scriptorium Estoniae

    2016-01-01

    Teemad: kasumiaruandest, sihtfinantseerimise kajastamisest tuluna, majandusaasta aruandest, sissemaksete osakapitali kajastamisest, mitteresidendist tööandja registreerimisest, töötaja töötasust mahaarvamiste kokkulepetest, välislähetuste päevarahadest

  20. Investigation of late iron age occupation layers in Viljandi castle park / Heiki Valk, Eve Rannamäe

    Index Scriptorium Estoniae

    Valk, Heiki, 1959-

    2015-01-01

    Tõenäoliselt kuulub uuritav leiumaterjal 11.- 12. sajandisse. Sel perioodil kasutati Viljandissamaaegselt nii kedra- kui käsitsikeraamikat. Leitud loomaluude hulgas on märkimisväärnselt suur osakaal kopraluudel. Vaatamata säilinud kultuurkihi väiksusele võimaldavad kaevamistulemused väita, et Viljandi muinaslinnuse vahetus läheduses, teiselpool vallikraavina toiminud looduslikku uhtorgu paiknes noorema rauaaja asula

  1. Autorsus ja tekstuaalsus : "Kalevipoeg" kui eepiline maastik / Ülo Valk ; inglise keelest tõlkinud Maili Pilt

    Index Scriptorium Estoniae

    Valk, Ülo, 1962-

    2003-01-01

    Artikli ingliskeelne versioon "Authorship and textuality: The Kalevipoeg as epic landscape" on ilmunud kogumikus "The Kalevala and the world's traditional epics" (toim. Lauri Honko). Helsinki : Finnish Literature Society, 2002.

  2. Laste jumalapilt ja usuõpetus usuvõõras kontekstis / Anna-Katharina Szagun ; tõlkinud Pille Valk

    Index Scriptorium Estoniae

    Szagun, Anna-Katharina

    2008-01-01

    Artikkel on kokkuvõte raamatus Dem sprachlosen Sprache verleihen. Rostocker Langzeitstudie zu Gottesverständis und Gottesbeziehung von Kindersm die in mehrheitlich konfessionslosem Kontext aufwachen (Paideia, 2006) publitseeritud uurimuse tulemustest

  3. Loomepõhine uurimistöö - mida see tähendab? / Claudia Pasquero ; intervjueerinud Veronika Valk

    Index Scriptorium Estoniae

    Pasquero, Claudia, 1974-

    2016-01-01

    Aprilli alguses peeti Eesti Kunstiakadeemia Arhitektuuriteaduskonnas ADAPT-r päeva, kus arutleti loomepõhise uurimistöö metodoloogia üle. Esinejate seas oli ka Londoni Ülikooli kolledži Bartlett`i Arhitektuurikooli õppejõud Claudia Pasquero. Intervjuus ta selgitab oma seisukohti loomepõhise doktorantuuri kohta linnaehituses ja arhitektuuris

  4. Lugejad küsivad - autorid vastavad : [teemad: kasumiaruandest...] / Toomas Villems, Madis Valk, Maire Otsus-Carpenter... [jt.

    Index Scriptorium Estoniae

    2016-01-01

    Teemad: kasumiaruandest, sihtfinantseerimise kajastamisest tuluna, majandusaasta aruandest, sissemaksete osakapitali kajastamisest, mitteresidendist tööandja registreerimisest, töötaja töötasust mahaarvamiste kokkulepetest, välislähetuste päevarahadest

  5. Investigation of late iron age occupation layers in Viljandi castle park / Heiki Valk, Eve Rannamäe

    Index Scriptorium Estoniae

    Valk, Heiki, 1959-

    2015-01-01

    Tõenäoliselt kuulub uuritav leiumaterjal 11.- 12. sajandisse. Sel perioodil kasutati Viljandissamaaegselt nii kedra- kui käsitsikeraamikat. Leitud loomaluude hulgas on märkimisväärnselt suur osakaal kopraluudel. Vaatamata säilinud kultuurkihi väiksusele võimaldavad kaevamistulemused väita, et Viljandi muinaslinnuse vahetus läheduses, teiselpool vallikraavina toiminud looduslikku uhtorgu paiknes noorema rauaaja asula

  6. Tallinna arhitektuuribiennaal arvamustes / Tomomi Hayashi, Andres Sevtšuk, Olga Maria Hungar ...[jt.] ; intervjueerinud Veronika Valk

    Index Scriptorium Estoniae

    2013-01-01

    Välisministeeriumi majast, näitusele viivast trepiinstallatsioonist, Singapuri tehnoloogia- ja disainiülikooli City Form Labi väljapanekust "Koolide näitusel" Tallinna Linnahallis, sotsialistlikust arhitektuurist ja nõukogude ruumipärandist, Väike-Õismäe visioonivõistlusest, arhitektide kui avaliku arvamuse kujundajate rollist

  7. Excavations in the ruins of Vastseliina castle and on the hillforts of Urvaste and Hinniala / Heiki Valk

    Index Scriptorium Estoniae

    Valk, Heiki, 1959-

    2007-01-01

    2006. aastal jätkusid kaevamised, mille eesmärk on tuua selgust Võrumaa kronoloogia küsimusse. Kaevamistest Vastseliina linnusel, Hinniala linnamäel (ka Päevapööramise mägi), mida on pärimuses peetud ohvripaigaks. Hinniala linnamäe seotusest ümbruskonna arheoloogiliste objektidega. Kaevamistest Urvaste (Järveküla) linnamäel

  8. Loomepõhine uurimistöö - mida see tähendab? / Claudia Pasquero ; intervjueerinud Marika Valk

    Index Scriptorium Estoniae

    Pasquero, Claudia, 1974-

    2016-01-01

    Aprilli alguses peeti Eesti Kunstiakadeemia Arhitektuuriteaduskonnas ADAPT-r päeva, kus arutleti loomepõhise uurimistöö metodoloogia üle. Esinejate seas oli ka Londoni Ülikooli kolledži Bartlett`i Arhitektuurikooli õppejõud Claudia Pasquero. Intervjuus ta selgitab oma seisukohti loomepõhise doktorantuuri kohta linnaehituses ja arhitektuuris

  9. Tallinna arhitektuuribiennaal arvamustes / Tomomi Hayashi, Andres Sevtšuk, Olga Maria Hungar ...[jt.] ; intervjueerinud Veronika Valk

    Index Scriptorium Estoniae

    2013-01-01

    Välisministeeriumi majast, näitusele viivast trepiinstallatsioonist, Singapuri tehnoloogia- ja disainiülikooli City Form Labi väljapanekust "Koolide näitusel" Tallinna Linnahallis, sotsialistlikust arhitektuurist ja nõukogude ruumipärandist, Väike-Õismäe visioonivõistlusest, arhitektide kui avaliku arvamuse kujundajate rollist

  10. Hotelli Palace**** renoveerimine = Renovation of the hotel Palace**** / Argo Vaikla

    Index Scriptorium Estoniae

    Vaikla, Argo, 1966-

    2015-01-01

    Hotell Palace Tallinnas Vabaduse väljak 3, valminud 2014. Hoone rekonstrueerimisprojekt Reet Valk (AB Reet Valk), sisearhitektid Katrin Vaikla, Argo Vaikla, Mari-Liis Süld, Riin Luuk. 2014. aasta Kultuurkapitali Arhitektuuripreemia kandidaat

  11. Hotelli Palace**** renoveerimine = Renovation of the hotel Palace**** / Argo Vaikla

    Index Scriptorium Estoniae

    Vaikla, Argo, 1966-

    2015-01-01

    Hotell Palace Tallinnas Vabaduse väljak 3, valminud 2014. Hoone rekonstrueerimisprojekt Reet Valk (AB Reet Valk), sisearhitektid Katrin Vaikla, Argo Vaikla, Mari-Liis Süld, Riin Luuk. 2014. aasta Kultuurkapitali Arhitektuuripreemia kandidaat

  12. Fluxgate gradiometry survey in the ruins of Karksi castle and palaeoenvironmental analysis in its hinterlands / Heiki Valk, Chantel Summerfield, Pluskowski, Alexander

    Index Scriptorium Estoniae

    Valk, Heiki, 1959-

    2009-01-01

    Gradiomeetriliste uuringute tulemused sobivad üldjoontes Karksi linnuse 17. sajandi plaaniga. Suurim erinevus ilmnes peavärava piirkonnas. Linnusest 5 km lõuna poolt võetud palünoloogiline analüüs näitab, varasematel metsamaastikel suureneb vahemikus 890-1040 pKr kanarbiku osakaal ja ilmuvad rukki õietolmuterad

  13. Field inventories in South-East Estonia in 2012 and 2013: archaeological monuments and sacred natural sites / Heiki Valk, Allar Haav, Anu-Liis Aunroos... [jt.

    Index Scriptorium Estoniae

    2014-01-01

    Muististe väljaselgitamine ja riikliku kaitse alla võtmine ei ole otseselt ühegi institutsiooni tööülesandeks. 2012. ja 2013. aastal toimus muististe väljaselgitamine Tartu Ülikooli arheoloogia kabineti eestvõttel Kagu-Eestis. Rootsiaegsetel kaartidel oleva info sidumiseks Eesti kaasaegse põhikaardiga töötati välja omaette metoodika. Välitööde käigus inventeeriti ka kuue kihelkonna looduslikud pühapaigad

  14. Excavations on the Hill Forts of South-East Estonia: Kureküla, Kõõru and Kuigatsi / Heiki Valk, Anti Lillak, Allar Haav, Tuuli Kurisoo

    Index Scriptorium Estoniae

    2013-01-01

    Kuremäe linnamäe näol on tõenäoliselt tegemist vaid ajutiselt kasutusel olnud või lõpetamata jäänud linnusega. Savinõukillud ja väikesemahulised kaitseehitised lubavad arvata, et linnus kuulub I aastatuhande teise poolde. Kuigatsi linnamäel võib keraamika põhjal eristada kaht kasutusetappi: rooma rauaaeg ja viikingiaeg. Eriliseks leiuks on rooma rauaaegne pronksisulatuskoht

  15. Field inventories in South-East Estonia in 2012 and 2013: archaeological monuments and sacred natural sites / Heiki Valk, Allar Haav, Anu-Liis Aunroos... [jt.

    Index Scriptorium Estoniae

    2014-01-01

    Muististe väljaselgitamine ja riikliku kaitse alla võtmine ei ole otseselt ühegi institutsiooni tööülesandeks. 2012. ja 2013. aastal toimus muististe väljaselgitamine Tartu Ülikooli arheoloogia kabineti eestvõttel Kagu-Eestis. Rootsiaegsetel kaartidel oleva info sidumiseks Eesti kaasaegse põhikaardiga töötati välja omaette metoodika. Välitööde käigus inventeeriti ka kuue kihelkonna looduslikud pühapaigad

  16. Fluxgate gradiometry survey in the ruins of Karksi castle and palaeoenvironmental analysis in its hinterlands / Heiki Valk, Chantel Summerfield, Pluskowski, Alexander

    Index Scriptorium Estoniae

    Valk, Heiki, 1959-

    2009-01-01

    Gradiomeetriliste uuringute tulemused sobivad üldjoontes Karksi linnuse 17. sajandi plaaniga. Suurim erinevus ilmnes peavärava piirkonnas. Linnusest 5 km lõuna poolt võetud palünoloogiline analüüs näitab, varasematel metsamaastikel suureneb vahemikus 890-1040 pKr kanarbiku osakaal ja ilmuvad rukki õietolmuterad

  17. The effect of clove-based herbal mouthwash on radiation-induced oral mucositis in patients with head and neck cancer: a single-blind randomized preliminary study

    OpenAIRE

    2016-01-01

    Moonkyoo Kong,1 Deok-Sang Hwang,2 Seong Woo Yoon,3 Jinsung Kim4 1Department of Radiation Oncology, Kyung Hee University Medical Center, Kyung Hee University School of Medicine, 2Department of Korean Medicine Obstetrics & Gynecology, Kyung Hee University Medical Center, 3Department of Korean Internal Medicine, Korean Medicine Cancer Center, Kyung Hee University Hospital at Gangdong, 4Department of Korean Internal Medicine, Kyung Hee University Medical Center, College of Korean Medicin...

  18. Памятник композитору Эдуарду Тубину, Тарту = Monument to the composer Eduard Tubin, Tartu / Илья Архипенко

    Index Scriptorium Estoniae

    Архипенко, Илья

    2010-01-01

    Eduard Tubina monumendist Tartus. Arhitekt Veronika Valk (Zizi & Yoyo), skulptor Aili Vahtrapuu. Kompleks koosneb kahest elemendist: traditsioonilisest mälestusmärgist ja interaktiivsest installatsioonist

  19. Vesi peale! Ikka ja jälle Tallinna sadamaala kujundamisest / Triin Ojari

    Index Scriptorium Estoniae

    Ojari, Triin, 1974-

    2007-01-01

    Tallinna sadamaala erinevatest planeeringutest ning arhitektuurikonkurssidest (Irina Raud, Veronika Valk, Villem Tomiste, Jan Verwijnen, Indrek Pottisep, Lembit Tork, Erik Konze, Taylor&Chapman). Näiteid Euroopast

  20. Panorama das teorias da comunicao Communication theories overview

    Directory of Open Access Journals (Sweden)

    Bianca Bonassi Ribeiro

    2012-01-01

    Full Text Available Francisco Rdiger ao longo do livro As teorias da comunicao constri um panorama crtico sobre algumas teorias da comunicao no campo social e filosfico. O autor transcorre sobre os fundamentos da teoria da comunicao, examina a Escola de Chicago, bem como os paradigmas funcionalista e materialista. Ao chegar Escola de Frankfurt concentra-se mais em Habermas. Por fim, conclui o livro discorrendo sobre o paradigma midiolgico contemporneo e seu impacto na comunicao e na sociedade.Throughout the book As teorias da communicao (the title in English means Communication theories, the author Francisco Rdiger, builds a critic overview about some Communication theories in the social and philosophical fields. The author goes by Communications theory fundaments, examines the Chicago School, as well as the functionalist and materialist paradigms. Once approaching the Frankfurt School he focuses more on Habermas. Finally, he finishes the book discussing the mediologic contemporary paradigm and its impact on Communication and society.

  1. 7. märtsini on Eesti Akadeemilises Raamatukogus väljas Adele Reindorffi 100. sünniaastapäevale pühendatud näituskonkursi tööd / Endel Valk-Falk

    Index Scriptorium Estoniae

    Valk-Falk, Endel, 1932-

    2001-01-01

    Reindorffi pärijate välja pandud preemia - Külli Grünbach-Sein, Raivo Vahtra, Silvi Kalda; Eesti Kultuuriministeeriumi preemia (T. Kirsipuu pronksbüst "Muusa") - Tiina Piisang; Eesti Köitekunstnike Ühenduse preemia -Tulvi-Hanneli Turo.

  2. The Iron Age and 13th-18th century Cemetery and Chapel Site of Niklusmägi : Grave Looting and Archaeology / Heiki Valk, Pikne Kama, Riina Rammo ... [jt.

    Index Scriptorium Estoniae

    2013-01-01

    2011. aastal anti arheoloogilidele vihje Niklusmäe kalme lõhkumisest. 2012. aasta suvel leidsid projekti "Arheoloogia, võim ja ühiskond" raames aset arheoloogilised päästeuuringud. Ilmnes, et kalmet oli rüüstatud 4-5 aasta jooksul. Leitud luustikest, hauapanustest. Niklusmäest Läti Henriku kroonika andmetel. Tänini räägib pärimus Lätist tulnud, Niklusmäe metsa läbivast ja Sangaste poole suunduvast sõjateest. Leiud on tõstatanud küsimusi Eesti lõunaserva matmiskommete ja etnokultuuriliste olude kohta. Kuna kalmesüdamik on rüüstatud, jäävad küsimused vastuseta

  3. The Iron Age and 13th-18th century Cemetery and Chapel Site of Niklusmägi : Grave Looting and Archaeology / Heiki Valk, Pikne Kama, Riina Rammo ... [jt.

    Index Scriptorium Estoniae

    2013-01-01

    2011. aastal anti arheoloogilidele vihje Niklusmäe kalme lõhkumisest. 2012. aasta suvel leidsid projekti "Arheoloogia, võim ja ühiskond" raames aset arheoloogilised päästeuuringud. Ilmnes, et kalmet oli rüüstatud 4-5 aasta jooksul. Leitud luustikest, hauapanustest. Niklusmäest Läti Henriku kroonika andmetel. Tänini räägib pärimus Lätist tulnud, Niklusmäe metsa läbivast ja Sangaste poole suunduvast sõjateest. Leiud on tõstatanud küsimusi Eesti lõunaserva matmiskommete ja etnokultuuriliste olude kohta. Kuna kalmesüdamik on rüüstatud, jäävad küsimused vastuseta

  4. Holographic entanglement entropy in imbalanced superconductors

    CERN Document Server

    Dutta, Arghya

    2014-01-01

    We study the behavior of holographic entanglement entropy (HEE) for imbalanced holographic superconductor. It is found that HEE for this imbalanced system decreases with the increase of imbalance in chemical potentials. Also for an arbitrary mismatch between two chemical potentials, below the critical temperature, superconducting phase has a lower HEE in comparison to the AdS-Reissner-Nordstrom black hole phase. This suggests entanglement entropy to be a useful physical probe for understanding the imbalanced holographic superconductors.

  5. Avatud ruumi mõttekoondaja / Elen Luht

    Index Scriptorium Estoniae

    Luht, Elen

    2013-01-01

    ADM Interactive'i kontori vihmavarju meenutavad valgustid, interjööri kujundasid sisearhitektid Ahti Grünberg, Kerli Valk, Tomomi Hayashi. Rootsi disainistuudio Form Us With Love kujundatud moodulitest koosnev valgusti

  6. Niguliste ümber krabiseb raha : kas muuseum või tegevkirik? / Madis Jürgen

    Index Scriptorium Estoniae

    Jürgen, Madis, 1962-

    1999-01-01

    Niguliste muuseum-kontsertsaali tegevkirikuks muutmise plaanist, pastoraadialusest maast, kiriku niiskuskliimast, lifti ehitamise vajadusest jm. Kommentaarid: M. Lagrekül, L. Pakosta, J. Kuuskemaa, R. Rüütel, M. Valk, T. Paul, T. Kaljuste.

  7. Age McCanni büroo = Offices of Age McCann

    Index Scriptorium Estoniae

    2010-01-01

    Tallinnas Rotermanni 8 asuva Age McCanni büroo sisekujundusest. Sisekujunduse autorid: sisearhitekt Kerli Valk (Kukuhaus OÜ) ja arhitekt Tomomi Hayashi (HG Arhitektuur OÜ), nende tähtsamate tööde loetelu

  8. Rakverega mängides = Playing with Rakvere / Lilia del Rio

    Index Scriptorium Estoniae

    Rio, Lilia del

    2006-01-01

    Rakvere peaväljaku renoveerimisest. Projekt: AB Kosmos. Detailplaneering: 2000, Ott Kadarik, Villem Tomiste, Veronika Valk. Projekt: 2004, Ott Kadarik, Villem Tomiste, Mihkel Tüür. Valmis 2005. Ill.: plaan, 4 värv. vaadet

  9. Research

    Index Scriptorium Estoniae

    2007-01-01

    TÜ teadlasi hinnatakse kõrgelt. EV teaduspreemiatele lisaks sai teaduse populariseerimise auhinna Ülo Valk, maailma suurim biomeditsiinifond Wellcome Trust tunnustas Mart Loogi, Eesti parima noore teadlase preemia pälvis Alar Aints

  10. Neues Kunstmuseum (KUMU)

    Index Scriptorium Estoniae

    2006-01-01

    Eesti Kunstimuuseumi uue hoone avamisest. Fotol Eesti Kunstimuuseumi peadirektor Marika Valk, president Arnold Rüütel, proua Ingrid Rüütel ja Soome president Tarja Halonen Kumu avamisel. Allk.: OA

  11. S vidom na Toompea / Jelena Kostina

    Index Scriptorium Estoniae

    Kostina, Jelena

    2002-01-01

    Eesti Kunstimuuseumi uue hoone ehituse pidulikust avamisest Kadrioru lossis, kus arhitekt Pekka Vapaavuori tutvustas muuseumihoone Circulos uut arhitektuurilist lahendust ja muuseumi direktor Marika Valk uue muuseumi tööprogramme ja funktsioone

  12. Tallinnasse Rävala pst. 19 kavandatava Tallinna Muusikakeskkooli, Tallinna Balletikooli ning G. Otsa nimelise muusikakooli ühise õppehoone arhitektuurikonkurss = Architectural Competition for the Joint School Building of Tallinn Music-Specialised

    Index Scriptorium Estoniae

    Puusepp, Raivo

    2003-01-01

    I preemia - Andres Siim, Krister Ausing, II - Marika Lõoke, III - Maia Tüür, Andres Sevtshuk, Gabriel Evangelisti, ostupreemiad: Armin Valter, Vilen Künnapu ning Siiri Vallner, Katrin Koov, Veronika Valk

  13. Age McCanni büroo = Offices of Age McCann

    Index Scriptorium Estoniae

    2010-01-01

    Tallinnas Rotermanni 8 asuva Age McCanni büroo sisekujundusest. Sisekujunduse autorid: sisearhitekt Kerli Valk (Kukuhaus OÜ) ja arhitekt Tomomi Hayashi (HG Arhitektuur OÜ), nende tähtsamate tööde loetelu

  14. Perekond Raus ENSV kaitseliinil / Valdur Ohmann

    Index Scriptorium Estoniae

    Ohmann, Valdur, 1958-

    2015-01-01

    Põhjalikumalt Oskar Rausi ja Viktor Rausi elukäigust. Viktor Rausi seostest tuntud eesti kultuuritegelastega: Jaanus Orgulas, Voldemar Panso, Jaak Joala, Arvo Pärt, Leonhard Lapin, Jüri Arrak, Aarne Vahtra, Heinz Valk, Ott Arder jt.

  15. Kuidas serveerida ajaloolist arhitektuuri? : märkmeid ja märkusi "Eesti ajalugu II : Eesti keskaeg" arhitektuurilõikude kohta / Kaur Alttoa

    Index Scriptorium Estoniae

    Alttoa, Kaur, 1947-

    2013-01-01

    Arvustus: Eesti ajalugu, II: Eesti keskaeg, koost ja toim Anti Selart, autorid Ivar Leimus, Kersti Markus, Anu Mänd, Inna Põltsam-Jürjo, Erki Russow, Anti Selart, Marek Tamm, Heiki Valk. Tartu: Tartu Ülikool 2012

  16. Küsitavused ja tugevused kaalukausil / Lauri Vahtre

    Index Scriptorium Estoniae

    Vahtre, Lauri, 1960-

    2013-01-01

    Arvustus: Eesti ajalugu, II: Eesti keskaeg, koost ja toim Anti Selart, autorid Ivar Leimus, Kersti Markus, Anu Mänd, Inna Põltsam-Jürjo, Erki Russow, Anti Selart, Marek Tamm, Heiki Valk. Tartu: Tartu Ülikool 2012

  17. Tallinnasse Rävala pst. 19 kavandatava Tallinna Muusikakeskkooli, Tallinna Balletikooli ning G. Otsa nimelise muusikakooli ühise õppehoone arhitektuurikonkurss = Architectural Competition for the Joint School Building of Tallinn Music-Specialised

    Index Scriptorium Estoniae

    Puusepp, Raivo

    2003-01-01

    I preemia - Andres Siim, Krister Ausing, II - Marika Lõoke, III - Maia Tüür, Andres Sevtshuk, Gabriel Evangelisti, ostupreemiad: Armin Valter, Vilen Künnapu ning Siiri Vallner, Katrin Koov, Veronika Valk

  18. 23. august 1989: Balti kett / koostanud Vesta Reest, Kadi Tarand

    Index Scriptorium Estoniae

    2013-01-01

    Balti riikide ühist protestiavaldust Molotovi-Ribbentropi pakti sõlmimise 50. aastapäeval meenutavad kunstnik Heinz Valk, Euroopa Kontrollikoja liige Kersti Kaljulaid ja Euroopa Parlamendi saadik Vilja Savisaar-Toomast

  19. Rakverega mängides = Playing with Rakvere / Lilia del Rio

    Index Scriptorium Estoniae

    Rio, Lilia del

    2006-01-01

    Rakvere peaväljaku renoveerimisest. Projekt: AB Kosmos. Detailplaneering: 2000, Ott Kadarik, Villem Tomiste, Veronika Valk. Projekt: 2004, Ott Kadarik, Villem Tomiste, Mihkel Tüür. Valmis 2005. Ill.: plaan, 4 värv. vaadet

  20. Koloneli sünnikohta tähistab mälestuskivi / Jaan Lukas

    Index Scriptorium Estoniae

    Lukas, Jaan, 1964-

    2006-01-01

    Eesti sõjaväe meditsiiniteenistuse kolonelile Hans Silbermannile avati tema sünnikohas Pajusi vallas Kalana külas Otisaare talu maadel mälestuskivi. Mälestuskivi plaadi ja teksti kujundas kunstnik Heinz Valk

  1. Neues Kunstmuseum (KUMU)

    Index Scriptorium Estoniae

    2006-01-01

    Eesti Kunstimuuseumi uue hoone avamisest. Fotol Eesti Kunstimuuseumi peadirektor Marika Valk, president Arnold Rüütel, proua Ingrid Rüütel ja Soome president Tarja Halonen Kumu avamisel. Allk.: OA

  2. Ekzotitsheskii protest / Ljubov Semjonova

    Index Scriptorium Estoniae

    Semjonova, Ljubov

    2004-01-01

    Jalgrattaliiklust toetav jalgratturite rahvusvaheline pikett Tallinnas pealinna autostumise vastu. Prussakovi-nimelise rattaühingu liider Erko Valk luges Vabaduse väljakul ette pöördumise Tallinna linnapeale Edgar Savisaarele

  3. Rahvakunst Marika ja Heinz Valgu kollektsioonist : Heie Treier soovitab / Heie Treier

    Index Scriptorium Estoniae

    Treier, Heie, 1963-

    2000-01-01

    12. märtsini Tarbekunstimuuseumis avatud näitusest, mille on kujundanud Heinz Valk. Soovitatakse külastada Kunstihoones Anu Juuraku näitust 'Tsoon 2', kus tegeldakse identiteedi probleemidega kõrgtehnoloogilisel tasandil.

  4. Aasta põllumehe teed viivad börsi asemel rappa / Silva Männik

    Index Scriptorium Estoniae

    Männik, Silva, 1974-

    2004-01-01

    Laheotsa talu peremees Johannes Valk roosi- ja köögiviljakasvatusest ning toodangu turustamisest. Kommenteerib Tõnis Oja. Diagrammid: Laheotsa talu. Vt. samas: Euroliidu abiprogrammid võtavad ära palju uneaega

  5. Üritatakse parimat, aga välja tuleb nagu tavaliselt / Alar Niineväli

    Index Scriptorium Estoniae

    Niineväli, Alar

    2009-01-01

    Bryan Singeri mängufilm "Operatsioon "Valküür"" ("Valkyrie"), peaosas Tom Cruise. Film räägib Claus von Stauffenbergi (1907-1944) poolt juhitud operatsioonist, mille eesmärgiks oli atendaat Adolf Hitlerile

  6. Lifelong learning on the market shelf

    DEFF Research Database (Denmark)

    Mehlsen, Camilla

    2009-01-01

    LEARNING CAPITALISM: Learning has been commodified in many parts of the world, and the growing learning market challenges public education in many ways, says Professor SoongHee Han.......LEARNING CAPITALISM: Learning has been commodified in many parts of the world, and the growing learning market challenges public education in many ways, says Professor SoongHee Han....

  7. Effects of Internal and External Hydrogen on Inconel 718

    Science.gov (United States)

    Walter, R. J.; Frandsen, J. D.

    1999-01-01

    Internal hydrogen embrittlement (IHE) and hydrogen environment embrittlement (HEE) tensile and bend crack growth tests were performed on Inconel 718. For the IHE tests, the specimens were precharged to approximately 90 ppm hydrogen by exposure to 34.5 MPa H2 at 650 C. The HEE tests were performed in 34.5 MPa H2. Parameters evaluated were test temperature, strain rate for smooth and notch specimen geometries. The strain rate effect was very significant at ambient temperature for both IHE and HEE and decreased with increasing temperatures. For IHE, the strain rate effect was neglible at 260'C, and for HEE the strain rate effect was neglible at 400 C. At low temperatures, IHE was more severe than HEE, and at high temperatures HEE was more severe than IHE with a cross over temperature about 350 C. At 350 C, the equilibrium hydrogen concentration in Inconel 718 is about 50% lower than the hydrogen content of the precharged IHE specimens. Dislocation hydrogen sweeping of surface absorbed hydrogen was the likely transport mechanism for increasing the hydrogen concentration in the HEE tests sufficiently to produce the same degree of embrittlement as that of the more highly hydrogen charged IHE specimens. The main IHE fracture characteristic was formation of large, brittle flat facets, which decreased with increasing test temperature. The IHE fracture matrix surrounding the large facets ranged between brittle fine faceted to microvoid ductility depending upon strain rate, specimen geometry as well as temperature. The HEE fractures were characteristically fine featured, transgranular and brittle with a significant portion forming a "saw tooth" crystallographic pattern. Both IHE and HEE fractures were predominantly along the {1 1 1) slip and twin boundaries. With respect to embrittlement mechanism, it was postulated that dislocation hydrogen sweeping and hydrogen enhanced localized plasticity were active in HEE and IHE for concentrating hydrogen along (1 1 1) slip and twin

  8. Characterization of Quantum Phase Transition using Holographic Entanglement Entropy

    CERN Document Server

    Ling, Yi; Wu, Jian-Pin

    2016-01-01

    We investigate the holographic entanglement entropy (HEE) in Einstein-Maxwell-Dilaton theory. In this framework black brane solutions with vanishing entropy density in zero temperature limit have been constructed in the presence of Q-lattice structure. We find that the first order derivative of HEE with repsect to lattice parameters exhibits the maximization behavior near quantum critical points (QCPs), which coincides with the phenomenon observed in realistic condensed matter system. Our discovery in this letter extends our previous observation in arXiv:1502.03661 where HEE itself diagnoses the quantum phase transition (QPT) with local extremes. We propose that it would be a univeral feature that HEE or its derivatives with respect to system parameters can characterize QPT in a generic holographic system.

  9. Iron-Deficiency Anemia

    Medline Plus

    Full Text Available ... easily treated condition that occurs if you don't have enough iron in your body. Low iron ... can occur if your red blood cells don't contain enough hemoglobin (HEE-muh-glow-bin). Hemoglobin ...

  10. Eat your troubles away: electrocortical and experiential correlates of food image processing are related to emotional eating style and emotional state.

    Science.gov (United States)

    Blechert, Jens; Goltsche, Julia E; Herbert, Beate M; Wilhelm, Frank H

    2014-02-01

    Emotional eating, a trait-like style of food intake in response to negative emotion states, represents an important aspect of overeating and eating related psychopathology. The mechanisms of emotional eating both on experiential and neuronal levels are not well delineated. We recorded event related potentials (ERPs) while individuals with high or low emotional eating style (HEE, n=25; LEE, n=20) viewed and rated pictures of high-caloric food during neutral state vs. negative idiosyncratic emotion induction. Craving ratings increased in HEE and decreased in LEE during negative relative to neutral states. ERPs to food pictures showed an enhanced late positive potential (LPP) over parieto-occipital regions for HEE compared to LEE. Emotional state modulated food picture evoked ERPs over right frontal regions in HEE only. This suggests that appetitive food processing is susceptible to both concurrent emotion and habitual eating style which is of relevance for overeating in healthy and abnormal eating.

  11. Influence of high pressure hydrogen environment on tensile and fatigue properties of stainless steels at low temperatures

    Science.gov (United States)

    Ogata, T.

    2012-06-01

    Hydrogen environment embrittlement (HEE) of stainless steels in the environment of high pressure and low temperature hydrogen gas was evaluated using a very simple mechanical properties testing procedure. In the method, the high-pressure hydrogen environment is produced just inside the hole in the specimen. In this work, the effects of HEE on fatigue properties for austenitic stainless steels SUS304L and SUS316L were evaluated at 298 and 190 K. The effects of HEE on the tensile properties of higher strength stainless steels, such as strain-hardened 316, SUS630, and other alloys, SUH660 and Alloy 718 were also examined. The less effect of HEE on fatigue properties of SUS316L and tensile properties of strain-hardened 316 were observed compared with SUS304L and other steels at room temperature and 190 K.

  12. Iron-Deficiency Anemia

    Medline Plus

    Full Text Available ... easily treated condition that occurs if you don't have enough iron in your body. Low iron ... can occur if your red blood cells don't contain enough hemoglobin (HEE-muh-glow-bin). Hemoglobin ...

  13. Quasi-free Pi0 and Pi- electroproduction on 4He in the Delta-resonance region (Pi en Delta in symbolen) - Zie als voorbeeld titelblad -

    NARCIS (Netherlands)

    Steenbakkers, M.F.M.

    2004-01-01

    The reactions 4He(e, e' p3He)pi- and 4He(e, e' p3He)pi0 were studied simultaneously, and for the first time, in a large kinematical domain including the Delta-resonance region. This was achieved by detecting the recoiling 3He and 3H nuclei instead of the emitted pions. The dependences of the cross

  14. Inhibition of Rac GTPases in the Therapy of Chronic Myelogenous Leukemia

    Science.gov (United States)

    2008-04-01

    Represent Integrating Molecular Therapeutic Targets for BCR-ABL-Induced Myeloproliferative Disease Emily K. Thomas,1,6 Jose A. Cancelas,1,2,6 Hee-Don...Integrating Molecular Therapeutic Targets for BCR-ABL-Induced Myeloproliferative Disease Emily K. Thomas, Jose A. Cancelas, Hee-Don Chae, Adrienne D. Cox... Dickinson ). Live cells were gated for analysis by forward and side scatter signals. 1. Williams, D.A., Tao, W., Yang, F.C., Kim, C., Gu, Y

  15. Burned and devoured-Introduced herbivores, fire, and the endemic flora of the high-elevation ecosystem on La Palma, Canary Islands

    OpenAIRE

    Irl, Severin D. H.; Steinbauer, Manuel; Messinger, Jana; Blume-Werry, Gesche; Palomares-Martinez, Angel; Beierkuhnlein, Carl; Jentsch, Anke

    2014-01-01

    Novel disturbance regimes (e.g., introduced herbivores and fire) are among the major drivers of degradation in island ecosystems. High-elevation ecosystems (HEEs) on islands might be especially vulnerable to these disturbances due to high endemism. Here, data from an 11-year exclosure experiment in the HEE of La Palma (Canary Islands) are presented where mammalian herbivores have been introduced. We investigate the combined effect of herbivory and fire on total species richness, seedling rich...

  16. Insight into the Role of Surface Wettability in Electrocatalytic Hydrogen Evolution Reactions Using Light-Sensitive Nanotubular TiO2 Supported Pt Electrodes.

    Science.gov (United States)

    Meng, Chenhui; Wang, Bing; Gao, Ziyue; Liu, Zhaoyue; Zhang, Qianqian; Zhai, Jin

    2017-02-06

    Surface wettability is of importance for electrochemical reactions. Herein, its role in electrochemical hydrogen evolution reactions is investigated using light-sensitive nanotubular TiO2 supported Pt as hydrogen evolution electrodes (HEEs). The HEEs are fabricated by photocatalytic deposition of Pt particles on TiO2 nanotubes followed by hydrophobization with vaporized octadecyltrimethoxysilane (OTS) molecules. The surface wettability of HEEs is subsequently regulated in situ from hydrophobicity to hydrophilicity by photocatalytic decomposition of OTS molecules using ultraviolet light. It is found that hydrophilic HEEs demonstrate a larger electrochemical active area of Pt and a lower adhesion force to a gas bubble when compared with hydrophobic ones. The former allows more protons to react on the electrode surface at small overpotential so that a larger current is produced. The latter leads to a quick release of hydrogen gas bubbles from the electrode surface at large overpotential, which ensures the contact between catalysts and electrolyte. These two characteristics make hydrophilic HEEs generate a much high current density for HERs. Our results imply that the optimization of surface wettability is of significance for improving the electrocatalytic activity of HEEs.

  17. Protective Effect of Ethanol Extracts of Hericium erinaceus on Alloxan-Induced Diabetic Neuropathic Pain in Rats

    Directory of Open Access Journals (Sweden)

    Zhang Yi

    2015-01-01

    Full Text Available We investigated the effects of Hericium erinaceus (HEE on alloxan induced diabetic neuropathic pain in laboratory rats. Alloxan induced diabetic rats were administered orally HEE. After 6 weeks of treatments, treatment with HEE 40 mg/kg in diabetic animals showed significant increase in pain threshold and paw withdrawal threshold and significant decrease in serum glucose and urine glucose. We also observed a significant increase in lactate dehydrogenase (LDH, Lipid peroxidation (LPO, glutathione peroxidase (GPx activity, glutathione reductase (GR activity, catalase (CAT activity, Na+K+ATPase activity, and glutathione S transferase (GST activity along with significant decreased levels of glutathione (GSH content in diabetic rats. The total antioxidant status (TAOS in the HEE-treated groups was significantly lower than that in the alloxan-treated group. HEE can offer pain relief in diabetic neuropathic pain. The improvement in diabetic state after HEE treatment along with the antioxidant activity could be the probable way by which it had alleviated diabetic neuropathy.

  18. Insight into the Role of Surface Wettability in Electrocatalytic Hydrogen Evolution Reactions Using Light-Sensitive Nanotubular TiO2 Supported Pt Electrodes

    Science.gov (United States)

    Meng, Chenhui; Wang, Bing; Gao, Ziyue; Liu, Zhaoyue; Zhang, Qianqian; Zhai, Jin

    2017-01-01

    Surface wettability is of importance for electrochemical reactions. Herein, its role in electrochemical hydrogen evolution reactions is investigated using light-sensitive nanotubular TiO2 supported Pt as hydrogen evolution electrodes (HEEs). The HEEs are fabricated by photocatalytic deposition of Pt particles on TiO2 nanotubes followed by hydrophobization with vaporized octadecyltrimethoxysilane (OTS) molecules. The surface wettability of HEEs is subsequently regulated in situ from hydrophobicity to hydrophilicity by photocatalytic decomposition of OTS molecules using ultraviolet light. It is found that hydrophilic HEEs demonstrate a larger electrochemical active area of Pt and a lower adhesion force to a gas bubble when compared with hydrophobic ones. The former allows more protons to react on the electrode surface at small overpotential so that a larger current is produced. The latter leads to a quick release of hydrogen gas bubbles from the electrode surface at large overpotential, which ensures the contact between catalysts and electrolyte. These two characteristics make hydrophilic HEEs generate a much high current density for HERs. Our results imply that the optimization of surface wettability is of significance for improving the electrocatalytic activity of HEEs. PMID:28165487

  19. Barriers to generalizability of health economic evaluations in Latin America and the Caribbean region.

    Science.gov (United States)

    Augustovski, Federico; Iglesias, Cynthia; Manca, Andrea; Drummond, Michael; Rubinstein, Adolfo; Martí, Sebastián García

    2009-01-01

    Use and acceptance of health economic evaluations (HEEs) has been much greater in developed than in developing nations. Nevertheless, while developing countries lag behind in the development of HEE methods, they could benefit from the progress made in other countries and concentrate on ways in which existing methods can be used or would need to be modified to fulfill their specific needs. HEEs, as context-specific tools, are not easily generalizable from setting to setting. Existing studies regarding generalizability and transferability of HEEs have primarily been conducted in developed countries. Therefore, a legitimate question for policy makers in Latin America and the Caribbean region (LAC) is to what extent HEEs conducted in industrialized economies and in LAC are generalizable to LAC (trans-regional) and to other LAC countries (intra-regional), respectively. We conducted a systematic review, searching the NHS Economic Evaluation Database (NHS EED), Office of Health Economics Health Economic Evaluation Database (HEED), LILACS (Latin America health bibliographic database) and NEVALAT (Latin American Network on HEE) to identify HEEs published between 1980 and 2004. We included individual patient- and model-based HEEs (cost-effectiveness, cost-utility, cost-benefit and cost-consequences analyses) that involved at least one LAC country. Data were extracted by three independent reviewers using a checklist validated by regional and international experts. From 521 studies retrieved, 72 were full HEEs (39% randomized controlled trials [RCTs], 32% models, 17% non-randomized studies and 12% mixed trial-modeling approach). Over one-third of identified studies did not specifically report the type of HEE. Cost-effectiveness and cost-consequence analyses accounted for almost 80% of the studies. The three Latin American countries with the highest participation in HEE studies were Brazil, Argentina and Mexico. While we found relatively good standards of reporting the study

  20. Small prize / Triin Ojari

    Index Scriptorium Estoniae

    Ojari, Triin, 1974-

    2010-01-01

    Eesti Arhitektide Liidu konkursi "Väike 2007-2009" 2009 võidutööd: Lasva veetorn Võrumaal (Veronika Valk, Kalle-Priit Pruuden, Peeter Laurits, Kalle Tikas), Tallinna Tehnikaülikooli esisele väljakule paigaldatud pingid (Martin Pärn, Edina Dufala-Pärn)

  1. Small prize / Triin Ojari

    Index Scriptorium Estoniae

    Ojari, Triin, 1974-

    2010-01-01

    Eesti Arhitektide Liidu konkursi "Väike 2007-2009" 2009 võidutööd: Lasva veetorn Võrumaal (Veronika Valk, Kalle-Priit Pruuden, Peeter Laurits, Kalle Tikas), Tallinna Tehnikaülikooli esisele väljakule paigaldatud pingid (Martin Pärn, Edina Dufala-Pärn)

  2. Eesti tööõpetuse alustalad / Endel Rihvk

    Index Scriptorium Estoniae

    Rihvk, Endel

    2005-01-01

    Lühiülevaade Eesti tööõpetuse õpetamisest ja suurkujudest: Eugen Bachblum, Villu Bauman, Agu Jaanson, August Kõrbe, Endel Land, Elmar Meiorg, Sergei Menshikov, Arseni Mölder, Geenart Nagel, Hans Niit, Arseni Reinumäe, Hugo Saaremets, Oleg Tefanov, Lembit Toome, Enno Toost, Julius Ungru, Priidu Valk, Ravo Vasari, Uno Vellomäe

  3. Benjamin Vassermanile preemiad

    Index Scriptorium Estoniae

    2007-01-01

    Graafik Benjamin Vasserman pälvis kolme digitaalse graafilise lehe eest žürii kiituse Ungaris Györis toimunud biennaalil "The Master of Drawing and Graphic Arts" ning II preemia nelja lehe eest Leedus Vilniuses toimunud VI rahvusvahelisel väikegraafika triennaalil. Eestist osalesid veel Reti Saks ja Kelli Valk

  4. Tänane Tartu - naerud, nutud ja hernetondid = Tartu today - laughter, tears and scarecrows / Berk Vaher

    Index Scriptorium Estoniae

    Vaher, Berk, 1975-

    2006-01-01

    Tartu linnaruumist, selle teisenemistest. Eduard Tubina mälestusmärgist (skulptor Aili Vahtrapuu, arhitekt Veronika Valk, heli: Louis Dandrel), Tartu Kaubamajast (arhitekt Raivo Puusepp), Rüütli tänava kujundusest (Rene Valner, Ott Kadarik), Ülikooli tänavast. 5 värv. ill

  5. Uus Sakala arhitektuurivõistlus = The Uus Sakala architectural competition / Panu Lehtovuori

    Index Scriptorium Estoniae

    Lehtovuori, Panu, 1968-

    2003-01-01

    Žürii liige konkursist: keskuse asukohast ja programmist, praeguse Sakala keskuse kasutamisest, konkursi tulemusest. Teise vooru valiti kolm projekti: võidutöö "Küpsis" (autorid Toomas Tammis, Inga Raukas, Tarmo Teedumäe, ArhitektuuriAgentuur), "Ocularis" (autorid Siiri Vallner, Indrek Peil), "Sõstrad" (autor Veronika Valk)

  6. Eesti Vabaõhumuuseumi külastuskeskus - ennistuskoda Kanut - Tallinna muuseumide ühishoidla arhitektuurne ideevõistlus = Estonian Open Air Museum Visitor Centre - Kanut Restoration Centre - Joint Depository for Tallinn museums : an Idea Competitio

    Index Scriptorium Estoniae

    Põdra, Laila, 1967-

    2007-01-01

    Ideekonkursi eesmärgist, I preemia pälvinud tööst "Raudjas" (autorid: Siiri Vallner, Imdrek Peil), ostupreemia pälvinud töödest "Leevike" (autor AB Kosmos: Ott Kadarik, Mihkel Tüür, Villem Tomiste) ja "Vurr" (autorid: Leena Torim, Maia Tüür, Veronika Valk)

  7. Narva keskosa planeeringu võistlus = Narva Central Area Planning Competition

    Index Scriptorium Estoniae

    2001-01-01

    Rahvusvahelise arhitektuurivõistluse zürii koosseis. Preemiad: I - Inga Raukas, Toomas Tammis, Tarmo Teedumäe; II - Erik Nobel (Kopenhaagen); III - Mark Hemel, Barbara Kuit (London); ost - Villem Tomiste ja Veronika Valk ning Richard Havenhand, Gregg Wilson ja Steve Kemp (Lincoln, Inglismaa).

  8. Ilmunud

    Index Scriptorium Estoniae

    2006-01-01

    Kirjastuselt "Maalehe Raamat" ilmusid Anders R. Dagsbergi ja Bertil K. Johansoni raamat "Aia planeerimine" ning Inger Palmstierna "Puud ja põõsad aias". Lk. 11: "Eesti Entsüklopeediakirjastuselt" ilmus Martti Soosaare raamat "Heinz Valk. 200 nägu"

  9. Saku Suurhall Rocca al Mares = Saku Suurhall in Rocca al Mare / Inga Raukas

    Index Scriptorium Estoniae

    Raukas, Inga, 1967-

    2001-01-01

    Peaprojekteerija, detailplaneering: Nord Projekt AS. Arhitektid Esa Viitanen (Soome), Andres Kariste, kaastöö: Meeli Truu, Loomet Raudsepp. Sisekujundus: Eero Jürgenson, Maarja Valk-Falk, Tambet Pedak, ARS Interjöörprojekt. Konstruktsioonid: Kaido Kuusiku, Tiit Arumäe, Aive Sau, Jaan Port. Projekteerimise projektijuht Andres Mikker. Projekt 1999-2001, valmis 2001. 9 ill

  10. Doktoriväitekiri Korea šamanismist / Aado Lintrop

    Index Scriptorium Estoniae

    Lintrop, Aado, 1956-

    2013-01-01

    Tutvustus: Jinseok Seo. The role of shamanism in Korea society in its inter- and intra-cultural contacts. Tartu : University of Tartu Press, 2013. (Dissertationes folkloristicae Universitatis Tartuensis ; 20). Doktoriväitekirja kaitsmine 6.06 2013, juhendaja Ülo Valk

  11. Surnuist üles äratamine = Reviving the dead / David Crowley

    Index Scriptorium Estoniae

    Crowley, David, 1966-

    2012-01-01

    Eesti ekspositsioonist "Kui pikk on ühe maja elu?" 13. Venezia arhitektuuribiennaalil "Common Ground" (kuraator David Chipperfield). Tallinna Linnahalli minevikust ja praegusest olukorrast. Kuraator Tüüne-Kristin Vaikla, näituse autorid Urmo Vaikla, Tüüne-Kristin Vaikla, Ingel Vaikla, Maria Pukk, Ivar Lubjak, Veronika Valk. Saksa paviljoni näitusest "Reduce, reuse, recycle"

  12. Saku Suurhall Rocca al Mares = Saku Suurhall in Rocca al Mare / Inga Raukas

    Index Scriptorium Estoniae

    Raukas, Inga, 1967-

    2001-01-01

    Peaprojekteerija, detailplaneering: Nord Projekt AS. Arhitektid Esa Viitanen (Soome), Andres Kariste, kaastöö: Meeli Truu, Loomet Raudsepp. Sisekujundus: Eero Jürgenson, Maarja Valk-Falk, Tambet Pedak, ARS Interjöörprojekt. Konstruktsioonid: Kaido Kuusiku, Tiit Arumäe, Aive Sau, Jaan Port. Projekteerimise projektijuht Andres Mikker. Projekt 1999-2001, valmis 2001. 9 ill

  13. Guide to New Resources

    Science.gov (United States)

    He, Ming Fang; Sapp, Jeff; Botelho, Maria Jose; Nunez, Isabel; Scott-Simmons, Wynnetta; Johnson, Lincoln

    2013-01-01

    The theme of this column is African American Women's Memories of Racial Oppression and Segregation in the U.S. South and Its Relevance to Multicultural Education. The focus of the review is on Anne Valk and Leslie Brown's "Living with Jim Crow: African American Women and Memories of the Segregated South" (2010). In "Living with Jim…

  14. Post-ideology and post-conceptual architecture and urbanism in (Eastern) Europe / Marina Gržinić

    Index Scriptorium Estoniae

    Gržinić, Marina, 1958-

    2012-01-01

    Essee on kirjutatud Eesti ekspositsiooni "Kui pikk on ühe maja elu?" (näituse komissar Ülar Mark, kuraator Tüüne-Kristin Vaikla, autorid Tüüne-Kristin Vaikla, Urmo Vaikla, Ingel Vaikla, Maria Pukk. Ivar Lubjak, Veronika Valk) jaoks 13. Venezia arhitektuuribiennaalil "Common Ground" 2012. aastal

  15. Two Close Ones / Tiina Sarapu

    Index Scriptorium Estoniae

    Sarapu, Tiina

    2006-01-01

    Tallinna IV tarbekunstitriennaalist "Kaks lähedast" Eesti Tarbekunsti- ja Disainimuuseumis 18.03-21.05.2006. Esimese preemia said Kersti Laanmaa ja Tiit Rammul rühmitusest MUKI, teise preemia Caro Bärtling ja Piret Valk. Aukülaliseks inglise ehtekunstnik Wendy Ramshaw oma ehtesarjaga "Picasso's Ladies". Näituse kujundas 3+1 Arhitektid

  16. Aed kogu perele / Tiina Tammet

    Index Scriptorium Estoniae

    Tammet, Tiina, 1971-

    2006-01-01

    Võistlusel "Kodu kauniks 2005" noore aia preemia pälvinud Kaja ja Tõnu Savi perekonna aiast Veskimöldres Tallinnas. Aed kujundati koostöös Ülle ja Urmas Grishakoviga. Eramu projekteeris Veronika Valk. 9 värv. ill

  17. Doktoriväitekiri Korea šamanismist / Aado Lintrop

    Index Scriptorium Estoniae

    Lintrop, Aado, 1956-

    2013-01-01

    Tutvustus: Jinseok Seo. The role of shamanism in Korea society in its inter- and intra-cultural contacts. Tartu : University of Tartu Press, 2013. (Dissertationes folkloristicae Universitatis Tartuensis ; 20). Doktoriväitekirja kaitsmine 6.06 2013, juhendaja Ülo Valk

  18. Eesti Ekspressi Areeni viis aastapreemiat kogusummas 100000 krooni (à 20000 krooni) anti üle 10. XII Hobuveskis

    Index Scriptorium Estoniae

    2003-01-01

    Aastapreemia said Heie Treier "kunst.ee" toimetamise ja monograafia "Pärsimägi" eest, arhitektuuribüroo Kavakava (Siiri Vallner, Veronika Valk, Katrin Koov, Kaire Nõmm) arhitektuuri- ja linnaplaneerimisalase tegevuse ja diskussiooni elavdamise eest, Andres Maimik, Toomas Liiv ja Juku-Kalle Raid

  19. "Now Art Now Future" Leedus

    Index Scriptorium Estoniae

    2005-01-01

    Seitse näitust Baltimaade graafikast Vilniuses, Kaunases ja Klaipedas. Eestist osalesid P. Allik, I. Heamägi, L. Jõekalda, A. Kalm, M. Nukke, L. Ruben, M.-K. Ulas, S. Tamsalu, A. Vahtrapuu, K. Valk. Eesti kuraatorid M.-K. Ulas ja V. Thurlow

  20. Uus Sakala arhitektuurivõistlus = The Uus Sakala architectural competition / Panu Lehtovuori

    Index Scriptorium Estoniae

    Lehtovuori, Panu, 1968-

    2003-01-01

    Žürii liige konkursist: keskuse asukohast ja programmist, praeguse Sakala keskuse kasutamisest, konkursi tulemusest. Teise vooru valiti kolm projekti: võidutöö "Küpsis" (autorid Toomas Tammis, Inga Raukas, Tarmo Teedumäe, ArhitektuuriAgentuur), "Ocularis" (autorid Siiri Vallner, Indrek Peil), "Sõstrad" (autor Veronika Valk)

  1. Post-ideology and post-conceptual architecture and urbanism in (Eastern) Europe / Marina Gržinić

    Index Scriptorium Estoniae

    Gržinić, Marina, 1958-

    2012-01-01

    Essee on kirjutatud Eesti ekspositsiooni "Kui pikk on ühe maja elu?" (näituse komissar Ülar Mark, kuraator Tüüne-Kristin Vaikla, autorid Tüüne-Kristin Vaikla, Urmo Vaikla, Ingel Vaikla, Maria Pukk. Ivar Lubjak, Veronika Valk) jaoks 13. Venezia arhitektuuribiennaalil "Common Ground" 2012. aastal

  2. Unista. Taju. Kohane. Toida. Linnahalli 5 visiooni = Dream. Sense. Adapt. Feed. 5 visions for Linnahall

    Index Scriptorium Estoniae

    2012-01-01

    Tallinna Linnahalli visiooni töötuba Eesti Kunstiakadeemia, Eesti Maaülikooli ja Tallinna Ülikooli Balti Filmi- ja Meediakooli üliõpilastele 28.05.-01.06.2012. Juhendasid Maria Pukk, Ivar Lubjak ja Veronika Valk

  3. Viljandi Metsakalmistu kabeli arhitektuurivõistlus / Marko Männik

    Index Scriptorium Estoniae

    Männik, Marko

    2005-01-01

    Arhitektuurivõistluse tulemused: I ja II preemia - Andres Lember (MALE Arhitektid), III - Emil Urbel koostöös Ott Hirvesooga (AB Emil Urbel), ostupreemiad - Ott Kadarik, Villem Tomiste, Mihkel Tüür (AB Kosmos) ning Veronika Valk, Yoko Alender ja Tuuli Köller (Kavakava). Žürii koosseis

  4. Lasva veetorn = Lasva Water Tower / Margit Mutso

    Index Scriptorium Estoniae

    Mutso, Margit, 1966-

    2010-01-01

    Lasva veetorni rekonstrueerimisest klavertrepiga kunstigaleriiks-vaatetorniks. Arhitekt, idee autor Veronika Valk, kaasautor Kadri Klementi, klavertrepi teostus: Kalle-Priit Pruuden, trepi elektrooniline heli: Kalle Tikas, infostendid: Peeter Laurits. Žürii liige Kalle Komissarov žürii hinnangust EK arhitektuuri sihtkapitali 2009. a. väikeobjekti preemia pälvinud hoonele

  5. Kultuurilehe kolleegiumlased

    Index Scriptorium Estoniae

    2004-01-01

    B. Lukats (1945), E. Einmann (1955), M. Port (1963), J. Vares (1963), I. Torn (1969), J. Kangilaski (1979), V. Herkel (1981), E. Põldroos (1988), I. Raud (1988), H. Valk (1988), S. Helme (1991), I. Volkov (1991), K. Hallas (1998), H. Soans (2002), R. Varblane (2003) jpt.

  6. Implementation of a multi-institutional diffuse intrinsic pontine glioma autopsy protocol and characterization of a primary cell culture

    NARCIS (Netherlands)

    Caretti, V.; Jansen, M.H.; Vuurden, D.G. van; Lagerweij, T.; Bugiani, M.; Horsman, I.; Wessels, H.; Valk, P. van der; Cloos, J.; Noske, D.P.; Vandertop, W.P.; Wesseling, P.; Wurdinger, T.; Hulleman, E.; Kaspers, G.J.L.

    2013-01-01

    V. Caretti, M. H. A. Jansen, D. G. van Vuurden, T. Lagerweij, M. Bugiani, I. Horsman, H. Wessels, P. van der Valk, J. Cloos, D. P. Noske, W. P. Vandertop, P. Wesseling, T. Wurdinger, E. Hulleman and G. J. L. Kaspers (2013) Neuropathology and Applied Neurobiology39, 426-436 Implementation of a

  7. Eesti tööõpetuse alustalad / Endel Rihvk

    Index Scriptorium Estoniae

    Rihvk, Endel

    2005-01-01

    Lühiülevaade Eesti tööõpetuse õpetamisest ja suurkujudest: Eugen Bachblum, Villu Bauman, Agu Jaanson, August Kõrbe, Endel Land, Elmar Meiorg, Sergei Menshikov, Arseni Mölder, Geenart Nagel, Hans Niit, Arseni Reinumäe, Hugo Saaremets, Oleg Tefanov, Lembit Toome, Enno Toost, Julius Ungru, Priidu Valk, Ravo Vasari, Uno Vellomäe

  8. Kultuurilehe kolleegiumlased

    Index Scriptorium Estoniae

    2004-01-01

    B. Lukats (1945), E. Einmann (1955), M. Port (1963), J. Vares (1963), I. Torn (1969), J. Kangilaski (1979), V. Herkel (1981), E. Põldroos (1988), I. Raud (1988), H. Valk (1988), S. Helme (1991), I. Volkov (1991), K. Hallas (1998), H. Soans (2002), R. Varblane (2003) jpt.

  9. Two Close Ones / Tiina Sarapu

    Index Scriptorium Estoniae

    Sarapu, Tiina

    2006-01-01

    Tallinna IV tarbekunstitriennaalist "Kaks lähedast" Eesti Tarbekunsti- ja Disainimuuseumis 18.03-21.05.2006. Esimese preemia said Kersti Laanmaa ja Tiit Rammul rühmitusest MUKI, teise preemia Caro Bärtling ja Piret Valk. Aukülaliseks inglise ehtekunstnik Wendy Ramshaw oma ehtesarjaga "Picasso's Ladies". Näituse kujundas 3+1 Arhitektid

  10. Weird and wonderful worms

    NARCIS (Netherlands)

    Wassink, J.

    2015-01-01

    In the WaterLab, biotechnologist Steef de Valk is carrying out experiments with tubifex worms. These threadlike creatures are capable of reducing by half the quantity of sewage sludge from water treatment. No-one really understands how this works.

  11. Arvamused

    Index Scriptorium Estoniae

    2009-01-01

    Eesti Rahva Muuseumi uue hoone arhitektuurikonkursist, võidutööst "Memory Field". Kommenteerivad Aleksei Peterson, Signe Kivi, Merike Lang, Laine Jänes, Tõnis Lukas, Jaak Aaviksoo, Jaan Õunapuu, Marika Valk, Art Leete, Kaur Alttoa, Hemi Sakkov, Pekka Vapaavuori, Tiiu Talvistu, Pertti Pyhtilä, Margit Mutso, Martti Preem, Ants Juske

  12. Hiigelämblik kanali kohal ehk Kuidas ERMi uus hoone lõi kired lõkkele / Tarmo Michelson

    Index Scriptorium Estoniae

    Michelson, Tarmo, 1975-

    2006-01-01

    Eesti Rahva muuseumi uue hoone arhitektuurikonkursi võidutööst "Memory Field" (autorid itaalia arhitekt Dan Dorell, liibanoni arhitekt Lina Ghotmeh, jaapani arhitekt Tsuyoshi Tane). Kommenteerivad Jaanus Plaat, Tõnis Lukas, Karin Hallas-Murula, Raivo Palmaru, Laine Jänes, Marika Valk

  13. Passion House - kirega loodud valmismaja / Kersti Pikk

    Index Scriptorium Estoniae

    Pikk, Kersti

    2013-01-01

    Janar Toomesso ja Priit Vahe valmismajade projektist Passion Smart Design Houses. Valminud on moodulmaja mudel M1 (Architect 11 meeskond, peaarhitekt Eero Endjärv). Sisearhitektid Hannelore Kääramees, Kätlin Ölluk, Maarja Valk-Falk

  14. Mustjõe asumi planeerimiskonkurss = The Competition for Planning the Mustjõe Community / Veljo Kaasik

    Index Scriptorium Estoniae

    Kaasik, Veljo

    2002-01-01

    Tallinna Mustjõe asumi korterelamu ja puhkeala ruumilise planeerimise võistluse eeltingimustest, premeeritud töödest. I preemia - Villem Tomiste, Mihkel Tüür, Ott Kadarik, II - Margit Mutso (koos kaastöölistega), III - Veronika Valk

  15. Pärnu mnt. ja Järvevana tee vahelise ala planeerimiskonkurss = Planning Competition of the Area between Järvevana and Pärnu Roads / Kalle Komissarov

    Index Scriptorium Estoniae

    Komissarov, Kalle, 1976-

    2002-01-01

    Konkursist, zürii koosseis, võidutöödest. Võistlusala oli AS-i "Kalev" ja Tallinna Piimatööstuse territoorium. Preemiad: I - Nikolai Volkov, Liis Sagadi, II - Tarmo Teedumäe, Renee Puusepp, Karli Luik, Toomas Tammis, Inga Raukas, III - Veronika Valk, ostupreemiad - Alver Trummal Arhitektid ja büroo Kosmos

  16. I.L.U. kauplused = I.L.U. stores

    Index Scriptorium Estoniae

    2010-01-01

    Tallinnas Rocca al Mare kaubanduskeskuses, Tartus Lõunakeskuses ja Pärnus Pärnu Keskuses asuvate I.L.U. kosmeetikakaupkuste sisekujundusest. Sisekujunduse autorid: Triinu Kuub, Andro Kööp, Andri Valk (Torpedo OÜ), nende tähtsamate tööde loetelu. Graafiline disain: reklaamifirma Tank

  17. 5. novembril esitles... / Sirje Lauring-Vaska

    Index Scriptorium Estoniae

    Lauring Vaska, Sirje

    1998-01-01

    5. novembril esitles Endel Valk-Falk oma miniraamatut "Kolm viimast eluaastat Revali esmatrükkali Christofer Reusner vanema elus", mis tutvustab toonaseid arhitektuuri- ja kunstiobjekte ning isiksusi. Kujundaja Rene Haljasmäe. 1.-14. detsembrini Eesti Akadeemilises Raamatukogus miniraamatute konkurssnäitus, kus osalevad ka köitekunstnikud Rootsist ja Saksamaalt

  18. Innovaatiliste äriideede konkursi võitjad / Varje Sootak

    Index Scriptorium Estoniae

    Sootak, Varje, 1946-

    2006-01-01

    Ettevõtjatele, teadlastele ja üliõpilastele korraldatud NETS (New Entrepreneurs in Technology and Science) ettevõtlusprogrammi innovaatiliste äriideede konkursil selgusid 15 parimat, kellest mitmed on Tartu Ülikooli üliõpilased ja töötajad: Anton Litvinenko, Fred Valk, Madis Kauts, Mario Plaas, Marko Daljajev, Meelis Kaldalu, Reigo Ginter, Tanel Tarkmees

  19. Vananemise taga võib olla kahepalgeline geen / Tiit Kändler

    Index Scriptorium Estoniae

    Kändler, Tiit, 1948-

    2012-01-01

    Kui pärssida valku nimega TOR rapamütsiiniga, pikeneb pärmide ja loomade eluiga. Ka kaloripiirang aeglustab vananemist, mõjudes samale valgule. TOR on oluline valk kasvavas organismis. Jätkuv aktiivsus küpses eas takistab raku tegutsemist, kahjustab kudesid, mõjutab vananemist ja haiguste teket

  20. Rein Sillar : Kui argumente ei jätku, on hea KGB kaart välja tõmmata / Rein Sillar ; interv. Toomas Sildam

    Index Scriptorium Estoniae

    Sillar, Rein

    2001-01-01

    Eesti NSV KGB viimane esimees ei usu, et eestlased sooviksid minevikuhaavu lahti rebida. Vare-Shironini kokkuleppest KGB tegevuse lõpemisest Eestis, süümevandest, ENSV Riiklikust Julgeolekukomiteest. Kommenteerivad: Ain Kaalep, Peeter Olesk, Heinz Valk. Parlamendisaadik (P. Olesk)

  1. Neli linna ehk mängud miljonitega / Andres Lõo

    Index Scriptorium Estoniae

    Lõo, Andres

    2006-01-01

    Cardiffis toimunud arhitektuurikonverentsist "Urban Legacies II", alapealkirjaga "New Babylon". Constanti (1920-2005) installatsioonist "New Babylon", Cardiffist, Tallinnast, ettekannete põhjal Dubaist ja Kinshasast. Konverentsi raames oli Eestist väljas arhitektuuriobjekt "Transparent Black Box" (Veronika Valk, projektiga seotud Kadri Klementi)

  2. Vabadus võtta vabalt / Maria-Kristiina Soomre

    Index Scriptorium Estoniae

    Soomre, Maria-Kristiina, 1978-

    2004-01-01

    Tänavakunstinäitus "Paraad" Eesti Lähimineviku Okupatsioonide Muuseumis. Osalevad Tuukka & Kätlin Kaila ning Vaughan Baker (London), Jani Tolin ja Freeman (Helsingi), Aadam Kaarma, Anu Samarüütel, Tarrvi Laamann, Marko Mäetamm & Kaido Ole, Lazer, Väike J, Veronika Valk, Kaarel Kulbin, DJ Critical

  3. Täna kell 18.30 avatakse Okupatsioonide muuseumis...

    Index Scriptorium Estoniae

    2004-01-01

    Linnakultuuriaineline näitus "Paraad". Keskne idee on seotud rula kui eluhoiakuga. Osalevad Tuukka & Kätlin Kaila ning Vaughan Baker (London), Jani Tolin ja Freeman (Helsingi), Aadam Kaarma, Anu Samarüütel, Tarrvi Laamann, Marko Mäetamm & Kaido Ole, Lazer, Väike J, Veronika Valk, DJ Critical

  4. Eesti Kunstnike Liidu volikogu kogunes 19. XII 2005 Ku-Ku klubis

    Index Scriptorium Estoniae

    2006-01-01

    Vastuvõetud EKL-i 2006. a. eelarvest, Tallinna Linnagalerii tulevikust, tarbekunstinäituste vähesusest. SA Tallinna Kunstihoone nõukogu uueks liikmeks valiti Leonhard Lapin. EKL-i auliikmeteks valiti Edgar Valter, Lea Walter, Jaan Klõsheiko, Lembit Sarapuu, Heinz Valk ja Helge Pihelga

  5. Neli linna ehk mängud miljonitega / Andres Lõo

    Index Scriptorium Estoniae

    Lõo, Andres

    2006-01-01

    Cardiffis toimunud arhitektuurikonverentsist "Urban Legacies II", alapealkirjaga "New Babylon". Constanti (1920-2005) installatsioonist "New Babylon", Cardiffist, Tallinnast, ettekannete põhjal Dubaist ja Kinshasast. Konverentsi raames oli Eestist väljas arhitektuuriobjekt "Transparent Black Box" (Veronika Valk, projektiga seotud Kadri Klementi)

  6. Pärast ligi kümmet aastat restaureerimist avab 22. juulil publikule taas uksed Kadrioru loss... / Harry Liivrand

    Index Scriptorium Estoniae

    Liivrand, Harry, 1961-

    2000-01-01

    N. Michetti plaanide järgi 1718-1723 ehitatud lossi kolib jälle Eesti Kunstimuuseum, eksponeerides seal oma väliskunsti kollektsiooni. 18. mail tutvustasid lossi pressile kunstimuuseumi peadirektor M. Valk ja filiaali juhataja J. Kuuskemaa.

  7. Generation of Tunable Coherent Radiation in 3 Micrometers-5 Micrometers Region Using Semiconductor Lasers in External Cavities.

    Science.gov (United States)

    1987-11-01

    Nordland, and W. Wiegman , J. Appl. Phys. 47, 4509 (1976). 32. K. Vilhelmsson, B. Valk, and M. M. Salour, App[. Phys. Lett. 50, 13, (1987). •. ". 26 N fj *q,)F% *. TPRIT. -. Il Alh ’P % P Jft .P N Z %% --- - .- 0

  8. Benjamin Vassermanile preemiad

    Index Scriptorium Estoniae

    2007-01-01

    Graafik Benjamin Vasserman pälvis kolme digitaalse graafilise lehe eest žürii kiituse Ungaris Györis toimunud biennaalil "The Master of Drawing and Graphic Arts" ning II preemia nelja lehe eest Leedus Vilniuses toimunud VI rahvusvahelisel väikegraafika triennaalil. Eestist osalesid veel Reti Saks ja Kelli Valk

  9. Eesti Akadeemiline Raamatukogu kuulutab eesti raamatu aasta ürituste sarjas ja seoses eesti nahkehistöökunstnike õpetaja Adele Reindorfi 100. sünniaastapäevaga välja näituskonkursi

    Index Scriptorium Estoniae

    2000-01-01

    Objektiks on Endel Valk-Falgu Adele Reindorfile pühendatud vastne mälestusraamat 'Pärlikee' köidetuna erinevas teostuses. Tähtaeg 1. II 2001. Tööd pannakse välja A. Reindorfi tähtpäevanäitusel veebruaris 2001

  10. Haruldased köited näitusel

    Index Scriptorium Estoniae

    2001-01-01

    Nahakunstnik Adele Reindorffi 100. sünniaastapäevale pühendatud näitus Tartu Ülikooli Raamatukogus, kus eksponeeriti Endel Valk-Falgu Adele Reindorffile pühendatud mälestusteose "Pärlikee" köiteid

  11. Lasva veetorn = Lasva Water Tower / Margit Mutso

    Index Scriptorium Estoniae

    Mutso, Margit, 1966-

    2010-01-01

    Lasva veetorni rekonstrueerimisest klavertrepiga kunstigaleriiks-vaatetorniks. Arhitekt, idee autor Veronika Valk, kaasautor Kadri Klementi, klavertrepi teostus: Kalle-Priit Pruuden, trepi elektrooniline heli: Kalle Tikas, infostendid: Peeter Laurits. Žürii liige Kalle Komissarov žürii hinnangust EK arhitektuuri sihtkapitali 2009. a. väikeobjekti preemia pälvinud hoonele

  12. Innovaatiliste äriideede konkursi võitjad / Varje Sootak

    Index Scriptorium Estoniae

    Sootak, Varje, 1946-

    2006-01-01

    Ettevõtjatele, teadlastele ja üliõpilastele korraldatud NETS (New Entrepreneurs in Technology and Science) ettevõtlusprogrammi innovaatiliste äriideede konkursil selgusid 15 parimat, kellest mitmed on Tartu Ülikooli üliõpilased ja töötajad: Anton Litvinenko, Fred Valk, Madis Kauts, Mario Plaas, Marko Daljajev, Meelis Kaldalu, Reigo Ginter, Tanel Tarkmees

  13. Mustjõe asumi planeerimiskonkurss = The Competition for Planning the Mustjõe Community / Veljo Kaasik

    Index Scriptorium Estoniae

    Kaasik, Veljo

    2002-01-01

    Tallinna Mustjõe asumi korterelamu ja puhkeala ruumilise planeerimise võistluse eeltingimustest, premeeritud töödest. I preemia - Villem Tomiste, Mihkel Tüür, Ott Kadarik, II - Margit Mutso (koos kaastöölistega), III - Veronika Valk

  14. Eesti Vabaõhumuuseumi külastuskeskus - ennistuskoda Kanut - Tallinna muuseumide ühishoidla arhitektuurne ideevõistlus = Estonian Open Air Museum Visitor Centre - Kanut Restoration Centre - Joint Depository for Tallinn museums : an Idea Competitio

    Index Scriptorium Estoniae

    Põdra, Laila, 1967-

    2007-01-01

    Ideekonkursi eesmärgist, I preemia pälvinud tööst "Raudjas" (autorid: Siiri Vallner, Imdrek Peil), ostupreemia pälvinud töödest "Leevike" (autor AB Kosmos: Ott Kadarik, Mihkel Tüür, Villem Tomiste) ja "Vurr" (autorid: Leena Torim, Maia Tüür, Veronika Valk)

  15. Eesti Ekspressi Areeni viis aastapreemiat kogusummas 100000 krooni (à 20000 krooni) anti üle 10. XII Hobuveskis

    Index Scriptorium Estoniae

    2003-01-01

    Aastapreemia said Heie Treier "kunst.ee" toimetamise ja monograafia "Pärsimägi" eest, arhitektuuribüroo Kavakava (Siiri Vallner, Veronika Valk, Katrin Koov, Kaire Nõmm) arhitektuuri- ja linnaplaneerimisalase tegevuse ja diskussiooni elavdamise eest, Andres Maimik, Toomas Liiv ja Juku-Kalle Raid

  16. Hitleri tapmiskatse ekraanil / Timo Diener

    Index Scriptorium Estoniae

    Diener, Timo

    2009-01-01

    Kuidas sündis Bryan Singeri film "Operatsioon "Valküür"", peaosas Tom Cruise. Stsenaariumi autorid Christopher McQuarrie ja Nathan Alexander stsenaariumi sünnist, režissöör Bryan Singer filmivõtetest Saksamaal

  17. Arhitektuursest intelligentsist. Intelligentsest arhitektuurist / Johanna Jõekalda

    Index Scriptorium Estoniae

    Jõekalda, Johanna

    2012-01-01

    13. Venezia arhitektuuribiennaalist "Common Ground", kuraator David Chipperfield. Sloveenia paviljonis toimunud sümpoosionist "2112Ai 100 YC", kus arutleti 2012. a. kultuuripealinna Maribori planeeringuliste tulevikuprojektide üle. Eestit esindasid Eesti Kunstiakadeemia arhitektuuritudengite projektid "mariBIOr" ja "Manibor" (juhendajad: Veronika Valk, Toomas Tammis)

  18. Lasnamäe kaldapealsele ehitatakse traditsiooniline vene õigeusukirik / Merike Teder

    Index Scriptorium Estoniae

    Teder, Merike

    2005-01-01

    Lasnamäe Jumalaema kiriku arhitektuurikonkursist ja võitnud töödest. Võitis traditsioonilise õigeusukiriku projekt, autorid arhitekt Oleg Zhemtshugov ning tema Minski kolleegid Nikolai Jatko ja Jevgeni Kolomenkin. Ergutuspreemiad said Veronika Valk ja Yoko Alender ning Jüri Martson, Rasmus Reinolt ja Ivo-Martin Veelma

  19. Passion House - kirega loodud valmismaja / Kersti Pikk

    Index Scriptorium Estoniae

    Pikk, Kersti

    2013-01-01

    Janar Toomesso ja Priit Vahe valmismajade projektist Passion Smart Design Houses. Valminud on moodulmaja mudel M1 (Architect 11 meeskond, peaarhitekt Eero Endjärv). Sisearhitektid Hannelore Kääramees, Kätlin Ölluk, Maarja Valk-Falk

  20. Vöökirjatud veetorn Võrumaal / Tanel Veenre

    Index Scriptorium Estoniae

    Veenre, Tanel, 1977-

    2009-01-01

    Lasva renoveeritud veetornist (renoveerimisprojekt: arhitekt Veronika Valk), kus asub Veetorni galerii, mille dominant on mitmel häälel helisev klavertrepp (teostus: skulptor Kalle Pruuden, Kalle Tikas). Seintel on fotograaf Peeter Lauritsa ja ajaloolase Uuno Ojala koostatud piirkonda tutvustav püsiväljapanek

  1. Surnuist üles äratamine = Reviving the dead / David Crowley

    Index Scriptorium Estoniae

    Crowley, David, 1966-

    2012-01-01

    Eesti ekspositsioonist "Kui pikk on ühe maja elu?" 13. Venezia arhitektuuribiennaalil "Common Ground" (kuraator David Chipperfield). Tallinna Linnahalli minevikust ja praegusest olukorrast. Kuraator Tüüne-Kristin Vaikla, näituse autorid Urmo Vaikla, Tüüne-Kristin Vaikla, Ingel Vaikla, Maria Pukk, Ivar Lubjak, Veronika Valk. Saksa paviljoni näitusest "Reduce, reuse, recycle"

  2. Tänane Tartu - naerud, nutud ja hernetondid = Tartu today - laughter, tears and scarecrows / Berk Vaher

    Index Scriptorium Estoniae

    Vaher, Berk, 1975-

    2006-01-01

    Tartu linnaruumist, selle teisenemistest. Eduard Tubina mälestusmärgist (skulptor Aili Vahtrapuu, arhitekt Veronika Valk, heli: Louis Dandrel), Tartu Kaubamajast (arhitekt Raivo Puusepp), Rüütli tänava kujundusest (Rene Valner, Ott Kadarik), Ülikooli tänavast. 5 värv. ill

  3. Edgar Valter - mees, kes teeb, mida õigeks peab / Jaak Urmet

    Index Scriptorium Estoniae

    Urmet, Jaak, 1979-

    2005-01-01

    Portreelugu raamatuillustreerijast, karikaturistist ja lastekirjanikust Edgar Valterist. Meenutavad Leelo Tungal ja Heinz Valk. Valteri lühibiograafia. Mare Müürsepa kommentaar "Kirjanik Edgar Valter lubab lapsel rahumeeli laps olla". Kiek in de Kökis avati Edgar Valteri maalide näitus

  4. I.L.U. kauplused = I.L.U. stores

    Index Scriptorium Estoniae

    2010-01-01

    Tallinnas Rocca al Mare kaubanduskeskuses, Tartus Lõunakeskuses ja Pärnus Pärnu Keskuses asuvate I.L.U. kosmeetikakaupkuste sisekujundusest. Sisekujunduse autorid: Triinu Kuub, Andro Kööp, Andri Valk (Torpedo OÜ), nende tähtsamate tööde loetelu. Graafiline disain: reklaamifirma Tank

  5. Narva keskosa planeeringu võistlus = Narva Central Area Planning Competition

    Index Scriptorium Estoniae

    2001-01-01

    Rahvusvahelise arhitektuurivõistluse zürii koosseis. Preemiad: I - Inga Raukas, Toomas Tammis, Tarmo Teedumäe; II - Erik Nobel (Kopenhaagen); III - Mark Hemel, Barbara Kuit (London); ost - Villem Tomiste ja Veronika Valk ning Richard Havenhand, Gregg Wilson ja Steve Kemp (Lincoln, Inglismaa).

  6. The Role of YY1 in Prostate Cancer

    Science.gov (United States)

    2010-03-01

    cancer cells. J Biol Chem, 2005; 280(26):24428-24434. 5. Erkeland SJ, Valkhof M, Heijmans-Antonissen C, Delwel R, Valk PJ, Hermans MH and Touw IP...7260-74. 174. Alvarez-Salas LM, Benitez- Hess ML, Dipaolo JA. YY- 1 and c-Jun transcription factors participate in the repression of the human

  7. Unista. Taju. Kohane. Toida. Linnahalli 5 visiooni = Dream. Sense. Adapt. Feed. 5 visions for Linnahall

    Index Scriptorium Estoniae

    2012-01-01

    Tallinna Linnahalli visiooni töötuba Eesti Kunstiakadeemia, Eesti Maaülikooli ja Tallinna Ülikooli Balti Filmi- ja Meediakooli üliõpilastele 28.05.-01.06.2012. Juhendasid Maria Pukk, Ivar Lubjak ja Veronika Valk

  8. Pärnu mnt. ja Järvevana tee vahelise ala planeerimiskonkurss = Planning Competition of the Area between Järvevana and Pärnu Roads / Kalle Komissarov

    Index Scriptorium Estoniae

    Komissarov, Kalle, 1976-

    2002-01-01

    Konkursist, zürii koosseis, võidutöödest. Võistlusala oli AS-i "Kalev" ja Tallinna Piimatööstuse territoorium. Preemiad: I - Nikolai Volkov, Liis Sagadi, II - Tarmo Teedumäe, Renee Puusepp, Karli Luik, Toomas Tammis, Inga Raukas, III - Veronika Valk, ostupreemiad - Alver Trummal Arhitektid ja büroo Kosmos

  9. Carum carvi Linn (Umbelliferae) Attenuates Lipopolysaccharide ...

    African Journals Online (AJOL)

    (ELISA). Results: CCE alone did not exhibit any signs of cytotoxicity to BV-2 cells up to 200 µg/ml concentration. ... 1β, IL-6, nitric oxide (NO), prostaglandin E2 and toxic free radicals ..... Amor S, Puentes F, Baker D, van der Valk P. Inflammation ...

  10. Edgar Valter - mees, kes teeb, mida õigeks peab / Jaak Urmet

    Index Scriptorium Estoniae

    Urmet, Jaak, 1979-

    2005-01-01

    Portreelugu raamatuillustreerijast, karikaturistist ja lastekirjanikust Edgar Valterist. Meenutavad Leelo Tungal ja Heinz Valk. Valteri lühibiograafia. Mare Müürsepa kommentaar "Kirjanik Edgar Valter lubab lapsel rahumeeli laps olla". Kiek in de Kökis avati Edgar Valteri maalide näitus

  11. Vabadus võtta vabalt / Maria-Kristiina Soomre

    Index Scriptorium Estoniae

    Soomre, Maria-Kristiina, 1978-

    2004-01-01

    Tänavakunstinäitus "Paraad" Eesti Lähimineviku Okupatsioonide Muuseumis. Osalevad Tuukka & Kätlin Kaila ning Vaughan Baker (London), Jani Tolin ja Freeman (Helsingi), Aadam Kaarma, Anu Samarüütel, Tarrvi Laamann, Marko Mäetamm & Kaido Ole, Lazer, Väike J, Veronika Valk, Kaarel Kulbin, DJ Critical

  12. Täna kell 18.30 avatakse Okupatsioonide muuseumis...

    Index Scriptorium Estoniae

    2004-01-01

    Linnakultuuriaineline näitus "Paraad". Keskne idee on seotud rula kui eluhoiakuga. Osalevad Tuukka & Kätlin Kaila ning Vaughan Baker (London), Jani Tolin ja Freeman (Helsingi), Aadam Kaarma, Anu Samarüütel, Tarrvi Laamann, Marko Mäetamm & Kaido Ole, Lazer, Väike J, Veronika Valk, DJ Critical

  13. Kaasaegse kunsti sõlmpunkt kolib soolalao kunstisaalist KUMUsse / Maarin Ektermann

    Index Scriptorium Estoniae

    Ektermann, Maarin

    2005-01-01

    EKM näitusesaal Rotermanni soolalaos lõpetab tegevuse mais 2005. Näitusesaali tegevusest räägivad Eha Komissarov, Hanno Soans, Marika Valk, Mari Sobolev, Johannes Saar, Eve Kask, Marko Mäetamm ja Kaire Nurk

  14. Заговорщиков погубила растерянность / Борис Тух

    Index Scriptorium Estoniae

    Тух, Борис, 1946-

    2009-01-01

    Ameerika-Saksa 2008.a. ajalooline mängufilm-põnevik "Operatsioon "Valküür" ("Valkyrie") Hitlerile 1944.a. sooritatud ebaõnnestunud atendaadist, režissöör Bryan Singer, Claus von Stauffenbergi rollis Tom Cruise

  15. A systematic review of scope and quality of health economic evaluation studies in Vietnam.

    Directory of Open Access Journals (Sweden)

    Bach Xuan Tran

    Full Text Available INTRODUCTION: The application of health economic evaluation (HEE evidence can play an important role in strategic planning and policy making. This study aimed to assess the scope and quality of existing research, with the goal of elucidating implications for improving the use of HEE evidence in Vietnam. METHODS: A comprehensive search strategy was developed to search medical online databases (Medline, Google Scholar, and Vietnam Medical Databases to select all types of HEE studies except cost-only analyses. Two researchers assessed the quality of selected studies using the Quality of Health Economic Studies (QHES instrument. RESULTS: We selected 26 studies, including 6 published in Vietnam. The majority of these studies focused on infectious diseases (14 studies, with HIV being the most common topic (5 studies. Most papers were cost-effectiveness studies that measured health outcomes using DALY units. Using QHES, we found that the overall quality of HEE studies published internationally was much higher (mean score 88.7+13.3 than that of those published in Vietnam (mean score 67.3+22.9. Lack of costing perspectives, reliable data sources and sensitivity analysis were the main shortcomings of the reviewed studies. CONCLUSION: This review indicates that HEE studies published in Vietnam are limited in scope and number, as well as by several important technical errors or omissions. It is necessary to formalize the process of health economic research in Vietnam and to institutionalize the links between researchers and policy-makers. Additionally, the quality of HEE should be enhanced through education about research techniques, and the implementation of standard HEE guidelines.

  16. Methods for Health Economic Evaluation of Vaccines and Immunization Decision Frameworks: A Consensus Framework from a European Vaccine Economics Community.

    Science.gov (United States)

    Ultsch, Bernhard; Damm, Oliver; Beutels, Philippe; Bilcke, Joke; Brüggenjürgen, Bernd; Gerber-Grote, Andreas; Greiner, Wolfgang; Hanquet, Germaine; Hutubessy, Raymond; Jit, Mark; Knol, Mirjam; von Kries, Rüdiger; Kuhlmann, Alexander; Levy-Bruhl, Daniel; Perleth, Matthias; Postma, Maarten; Salo, Heini; Siebert, Uwe; Wasem, Jürgen; Wichmann, Ole

    2016-03-01

    Incremental cost-effectiveness and cost-utility analyses [health economic evaluations (HEEs)] of vaccines are routinely considered in decision making on immunization in various industrialized countries. While guidelines advocating more standardization of such HEEs (mainly for curative drugs) exist, several immunization-specific aspects (e.g. indirect effects or discounting approach) are still a subject of debate within the scientific community. The objective of this study was to develop a consensus framework for HEEs of vaccines to support the development of national guidelines in Europe. A systematic literature review was conducted to identify prevailing issues related to HEEs of vaccines. Furthermore, European experts in the field of health economics and immunization decision making were nominated and asked to select relevant aspects for discussion. Based on this, a workshop was held with these experts. Aspects on 'mathematical modelling', 'health economics' and 'decision making' were debated in group-work sessions (GWS) to formulate recommendations and/or--if applicable--to state 'pros' and 'contras'. A total of 13 different aspects were identified for modelling and HEE: model selection, time horizon of models, natural disease history, measures of vaccine-induced protection, duration of vaccine-induced protection, indirect effects apart from herd protection, target population, model calibration and validation, handling uncertainty, discounting, health-related quality of life, cost components, and perspectives. For decision making, there were four aspects regarding the purpose and the integration of HEEs of vaccines in decision making as well as the variation of parameters within uncertainty analyses and the reporting of results from HEEs. For each aspect, background information and an expert consensus were formulated. There was consensus that when HEEs are used to prioritize healthcare funding, this should be done in a consistent way across all interventions

  17. Alterations in Epidermal Eicosanoid Metabolism Contribute to Inflammation and Impaired Late Differentiation in FLG-Mutated Atopic Dermatitis.

    Science.gov (United States)

    Blunder, Stefan; Rühl, Ralph; Moosbrugger-Martinz, Verena; Krimmel, Christine; Geisler, Anita; Zhu, Huiting; Crumrine, Debra; Elias, Peter M; Gruber, Robert; Schmuth, Matthias; Dubrac, Sandrine

    2017-03-01

    Loss-of-function mutations in the FLG gene cause ichthyosis vulgaris (IV) and represent the major predisposing genetic risk factor for atopic dermatitis (AD). Although both conditions are characterized by epidermal barrier impairment, AD also exhibits signs of inflammation. This work was aimed at delineating the role of FLG loss-of-function mutations on eicosanoid metabolism in IV and AD. Using human epidermal equivalents (HEEs) generated with keratinocytes isolated from nonlesional skin of patients with FLG wild-type AD (WT/WT), FLG-mutated AD (FLG/WT), IV (FLG/FLG), or FLG WT control skin, we assessed the potential autocrine role of epidermal-derived eicosanoids in FLG-associated versus FLG-WT AD pathogenesis. Ultrastructural analyses demonstrated abnormal stratum corneum lipid architecture in AD and IV HEEs, independent of FLG genotype. Both AD (FLG/WT) and IV (FLG/FLG) HEEs showed impaired late epidermal differentiation. Only AD (FLG/WT) HEEs exhibited significantly increased levels of inflammatory cytokines. Analyses of lipid mediators revealed increased arachidonic acid and 12-lipoxygenase metabolites. Whereas treatment of control HEEs with arachidonic acid increased expression of inflammatory cytokines, 12-hydroxy-eicosatetraenoic acid attenuated expression of late differentiation markers. Thus, FLG mutations lead to alterations in epidermal eicosanoid metabolism that could serve as an autocrine trigger of inflammation and impaired late epidermal differentiation in AD.

  18. Holographic entanglement entropy of anisotropic minimal surfaces in LLM geometries

    Science.gov (United States)

    Kim, Chanju; Kim, Kyung Kiu; Kwon, O.-Kab

    2016-08-01

    We calculate the holographic entanglement entropy (HEE) of the Zk orbifold of Lin-Lunin-Maldacena (LLM) geometries which are dual to the vacua of the mass-deformed ABJM theory with Chern-Simons level k. By solving the partial differential equations analytically, we obtain the HEEs for all LLM solutions with arbitrary M2 charge and k up to μ02 -order where μ0 is the mass parameter. The renormalized entanglement entropies are all monotonically decreasing near the UV fixed point in accordance with the F-theorem. Except the multiplication factor and to all orders in μ0, they are independent of the overall scaling of Young diagrams which characterize LLM geometries. Therefore we can classify the HEEs of LLM geometries with Zk orbifold in terms of the shape of Young diagrams modulo overall size. HEE of each family is a pure number independent of the 't Hooft coupling constant except the overall multiplication factor. We extend our analysis to obtain HEE analytically to μ04 -order for the symmetric droplet case.

  19. Holographic entanglement entropy of anisotropic minimal surfaces in LLM geometries

    Directory of Open Access Journals (Sweden)

    Chanju Kim

    2016-08-01

    Full Text Available We calculate the holographic entanglement entropy (HEE of the Zk orbifold of Lin–Lunin–Maldacena (LLM geometries which are dual to the vacua of the mass-deformed ABJM theory with Chern–Simons level k. By solving the partial differential equations analytically, we obtain the HEEs for all LLM solutions with arbitrary M2 charge and k up to μ02-order where μ0 is the mass parameter. The renormalized entanglement entropies are all monotonically decreasing near the UV fixed point in accordance with the F-theorem. Except the multiplication factor and to all orders in μ0, they are independent of the overall scaling of Young diagrams which characterize LLM geometries. Therefore we can classify the HEEs of LLM geometries with Zk orbifold in terms of the shape of Young diagrams modulo overall size. HEE of each family is a pure number independent of the 't Hooft coupling constant except the overall multiplication factor. We extend our analysis to obtain HEE analytically to μ04-order for the symmetric droplet case.

  20. Holographic Entanglement Entropy of Anisotropic Minimal Surfaces in LLM Geometries

    CERN Document Server

    Kim, Chanju; Kwon, O-Kab

    2016-01-01

    We calculate the holographic entanglement entropy (HEE) of the $\\mathbb{Z}_k$ orbifold of Lin-Lunin-Maldacena (LLM) geometries which are dual to the vacua of the mass-deformed ABJM theory with Chern-Simons level $k$. By solving the partial differential equations analytically, we obtain the HEEs for all LLM solutions with arbitrary M2 charge and $k$ up to $\\mu_0^2$-order where $\\mu_0$ is the mass parameter. The renormalized entanglement entropies are all monotonically decreasing near the UV fixed point in accordance with the $F$-theorem. Except the multiplication factor and to all orders in $\\mu_0$, they are independent of the overall scaling of Young diagrams which characterize LLM geometries. Therefore we can classify the HEEs of LLM geometries with $\\mathbb{Z}_k$ orbifold in terms of the shape of Young diagrams modulo overall size. HEE of each family is a pure number independent of the 't Hooft coupling constant except the overall multiplication factor. We extend our analysis to obtain HEE analytically to $...

  1. Holographic Metal-Insulator Transition in Higher Derivative Gravity

    CERN Document Server

    Ling, Yi; Wu, Jian-Pin; Zhou, Zhenhua

    2016-01-01

    We introduce a Weyl term into the Einstein-Maxwell-Axion theory in four dimensional spacetime. Up to the first order of the Weyl coupling parameter $\\gamma$, we construct charged black brane solutions without translational invariance in a perturbative manner. Among all the holographic frameworks involving higher derivative gravity, we are the first to obtain metal-insulator transitions (MIT) when varying the system parameters at zero temperature. Furthermore, we study the holographic entanglement entropy (HEE) of strip geometry in this model and find that the second order derivative of HEE with respect to the axion parameter exhibits maximization behavior near quantum critical points (QCPs) of MIT. It testifies the conjecture in 1502.03661 and 1604.04857 that HEE itself or its derivatives can be used to diagnose quantum phase transition (QPT).

  2. Holographic metal-insulator transition in higher derivative gravity

    Directory of Open Access Journals (Sweden)

    Yi Ling

    2017-03-01

    Full Text Available We introduce a Weyl term into the Einstein–Maxwell-Axion theory in four dimensional spacetime. Up to the first order of the Weyl coupling parameter γ, we construct charged black brane solutions without translational invariance in a perturbative manner. Among all the holographic frameworks involving higher derivative gravity, we are the first to obtain metal-insulator transitions (MIT when varying the system parameters at zero temperature. Furthermore, we study the holographic entanglement entropy (HEE of strip geometry in this model and find that the second order derivative of HEE with respect to the axion parameter exhibits maximization behavior near quantum critical points (QCPs of MIT. It testifies the conjecture in [1,2] that HEE itself or its derivatives can be used to diagnose quantum phase transition (QPT.

  3. Holographic metal-insulator transition in higher derivative gravity

    Science.gov (United States)

    Ling, Yi; Liu, Peng; Wu, Jian-Pin; Zhou, Zhenhua

    2017-03-01

    We introduce a Weyl term into the Einstein-Maxwell-Axion theory in four dimensional spacetime. Up to the first order of the Weyl coupling parameter γ, we construct charged black brane solutions without translational invariance in a perturbative manner. Among all the holographic frameworks involving higher derivative gravity, we are the first to obtain metal-insulator transitions (MIT) when varying the system parameters at zero temperature. Furthermore, we study the holographic entanglement entropy (HEE) of strip geometry in this model and find that the second order derivative of HEE with respect to the axion parameter exhibits maximization behavior near quantum critical points (QCPs) of MIT. It testifies the conjecture in [1,2] that HEE itself or its derivatives can be used to diagnose quantum phase transition (QPT).

  4. Thermodynamics and holographic entanglement entropy for spherical black holes in 5D Gauss-Bonnet gravity

    CERN Document Server

    Sun, Yuan; Zhao, Liu

    2016-01-01

    The holographic entanglement entropy is studied numerically in (4+1)-dimensional spherically symmetric Gauss-Bonnet AdS black hole spacetime with compact boundary. On the bulk side the black hole spacetime undergoes a van der Waals-like phase transition in the extended phase space, which is reviewed with emphasis on the behavior on the temperature-entropy plane. On the boundary, we calculated the regularized HEE of a disk region of different sizes. We find strong numerical evidence for the failure of equal area law for isobaric curves on the temperature-HEE plane and for the correctness of first law of entanglement entropy, and briefly give an explanation for why the latter may serve as a reason for the former, i.e. the failure of equal area law on the temperature-HEE plane.

  5. Thermodynamics and holographic entanglement entropy for spherical black holes in 5D Gauss-Bonnet gravity

    Science.gov (United States)

    Sun, Yuan; Xu, Hao; Zhao, Liu

    2016-09-01

    The holographic entanglement entropy is studied numerically in (4+1)-dimensional spherically symmetric Gauss-Bonnet AdS black hole spacetime with compact boundary. On the bulk side the black hole spacetime undergoes a van der Waals-like phase transition in the extended phase space, which is reviewed with emphasis on the behavior on the temperature-entropy plane. On the boundary, we calculated the regularized HEE of a disk region of different sizes. We find strong numerical evidence for the failure of equal area law for isobaric curves on the temperature-HEE plane and for the correctness of first law of entanglement entropy, and briefly give an explanation for why the latter may serve as a reason for the former, i.e. the failure of equal area law on the temperature-HEE plane.

  6. Reference: 511 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available 511 http://metadb.riken.jp/db/SciNetS_ria224i/cria224u4ria224u17217467i Yoo Hyun Hee et al. 2007 Fe...ons in AtWHY1. These lines exhibit neither growth nor developmental defects. However, AtWHY1-deficient plant...mere length homeostasis in Arabidopsis. 3 442-51 17217467 2007 Feb The Plant journal Chung In Kwon|Kwon Chian|Lee Myeong Min|Yoo Hyun Hee

  7. Studies on the Electron Reconstruction Efficiency for the Beam Calorimeter of an ILC Detector

    CERN Document Server

    Novgorodova, Olga

    2010-01-01

    In this talk recent simulation results on the single high energy electron reconstruction with the Beam Calorimeter for the ILD detector are presented. Guinea Pig is used to generate the e+e- pair background and GEANT4 for the simulation of electron showers in the calorimeter. An algorithm was developed for the sHEe reconstruction on top of the large e+e- background. The efficiency of the sHEe reconstruction is estimated for the nominal and SB-2009 ILC beam parameters.

  8. Arhitektuurivõistlused 2002 / Ingrid Lillemägi

    Index Scriptorium Estoniae

    Lillemägi, Ingrid

    2002-01-01

    Tulemused: Vabaduse väljaku või selle lähiümbruse Vabaduse monumendi kavandivõistluse II etapp (II - M. Pukk, I. Lubjak); Tallinna sadama Admiraliteedi mahuline linnaplaneering (I-II - J. Verwijnen, T. Kauppila, H. Määtanen (Soome), V. Tomiste); Tallinna vanasadama ala ruumiline planeerimine (väljavalitud tööd: "Oaas" - I. Pottisep, L. Tork, E. Konze, "Peatänav" - V. Tomiste, "Magnet" - T. Sild, M. Kask, I. Järve); Tallinna piiritähis (I -V. Valk, M. Valk); Järvevana tee ja Pärnu mnt. vahelise ala arhitektuurivõistlus (I - N. Volkov, L. Sagadi); Narvas Tallinna mnt. ja Kangelaste prospekti ristmiku planeering (II - E. Nobel); Mustjõe asumi korterelamu ja puhkeala ruumiline planeerimine (I - O. Kadarik, V. Tomiste, M. Tüür, büroo Kosmos)

  9. Arhitektuurivõistlused 2002 / Ingrid Lillemägi

    Index Scriptorium Estoniae

    Lillemägi, Ingrid

    2002-01-01

    Tulemused: Vabaduse väljaku või selle lähiümbruse Vabaduse monumendi kavandivõistluse II etapp (II - M. Pukk, I. Lubjak); Tallinna sadama Admiraliteedi mahuline linnaplaneering (I-II - J. Verwijnen, T. Kauppila, H. Määtanen (Soome), V. Tomiste); Tallinna vanasadama ala ruumiline planeerimine (väljavalitud tööd: "Oaas" - I. Pottisep, L. Tork, E. Konze, "Peatänav" - V. Tomiste, "Magnet" - T. Sild, M. Kask, I. Järve); Tallinna piiritähis (I -V. Valk, M. Valk); Järvevana tee ja Pärnu mnt. vahelise ala arhitektuurivõistlus (I - N. Volkov, L. Sagadi); Narvas Tallinna mnt. ja Kangelaste prospekti ristmiku planeering (II - E. Nobel); Mustjõe asumi korterelamu ja puhkeala ruumiline planeerimine (I - O. Kadarik, V. Tomiste, M. Tüür, büroo Kosmos)

  10. Milleks monumenti = Why a monument? / Heie Treier

    Index Scriptorium Estoniae

    Treier, Heie, 1963-

    2006-01-01

    2006. a. toimunud Jüri Lotmani mälestusmärgi konkursist, Mati Karmini ja Andres Lunge võidutööst. Monumentide positiivseid näiteid: Tubina plats Tartus (Aili Vahtrapuu, Veronika Valk, Louis Dandrel), ideekavandid: Estonia teatri juubelimonument Tallinnas (Tiiu Kirsipuu, Üla Koppel) ja Eesti iseseisvuse monument Pärnus Rüütli platsil (Mart Aas, Kaarel Eelma, Mikk Mutso). Bibl. lk. 73

  11. Triennaalist ja preemiatest : tarbekunst / Lesley Jackson ; tõlk. Kai Lobjakas

    Index Scriptorium Estoniae

    Jackson, Lesley

    2006-01-01

    Inglise disainiajaloolane, auhinnažürii liige Eesti Tarbekunsti- ja Disainimuuseumis avatud IV Tallinna rakenduskunsti triennaalist "Kaks lähedast" ja preemia saanud töödest. Näituse kujundus: 3+1 Arhitektid. I preemia: Kersti Laanmaa ja Tiit Rammuli (rühmitus Muki) töö "Loomaarmastus", kaks teist preemiat: Piret Valk "Maa vägi", Caro Bärtling "Salvrätt-kraed"

  12. Büroo ADM Interactive = Office ADM Interactive

    Index Scriptorium Estoniae

    2011-01-01

    Eesti Sisearhitektide Liidu 2010. a. ühiskondliku interjööri preemia pälvinud ADM Interactive'i büroost Tallinnas Rotermanni 8. Sisekujunduse autorid: arhitekt Tomomi Hayashi (HG Arhitektuur), sisearhitektid Ahti Grünberg (CadStudio OÜ) ja Kerli Valk (Kukuhaus OÜ), loetletud nende töid. Laelambid valmisid sisekujundajate jooniste järgi Hansanovas

  13. Sadamaala konkurss : Tallinna kesklinnaga piirneva mereäärse ala parima linnaehitusliku kontseptsiooni saamiseks korraldatud arhitektuurivõistlus / Andres Alver, Margus Koot, Arvo Rikkinen...[jt.] ; interv. Triin Ojari

    Index Scriptorium Estoniae

    2000-01-01

    Zürii liikmed konkursist, premeeritud töödest. Preemiad: I - Villem Tomiste, Veronika Valk; II - Illimar Truverk, Indrek Järve, Mattias Agabus, Tiit Sild, Karri Tiigisoon ning Toomas Paaver, Lauri Saar; III - Ivar Lubjak, Maria Pukk; ostud: Ott Kadarik, Rene Valner ning Siiri Vallner, Indrek Peil; täiendav ost (Muinsuskaitseamaet): Nikolai Serebrjakov, Leonid Tozil, Sergei Sevtsenko, Sulev Roosmaa. 6 illustratsiooni

  14. Retrovõtmes pühamu / Karin Paulus

    Index Scriptorium Estoniae

    Paulus, Karin, 1975-

    2005-01-01

    Tallinnasse Lasnamäele plaanitava Jumalaema kiriku arhitektuurikonkursi võidutööst arhitektuuribüroolt Z-Projekt (arhitektid Oleg Zhemtshugov, Nikolai Djatko, Jevgeni Kolomenkin). Kommenteerib kunstiteadlane Mari-Liis Paaver. Ergutuspreemiad said arhitektuuribüroo ZiZi & YoYo projekt (arhitektid Veronika Valk, Yoko Alender) ning arhitektuuribüroo Lokomotiiv (arhitektid Jüri Martson, Rasmus Reinolt, Ivo-Martin Veelma)

  15. Triennaalist ja preemiatest : tarbekunst / Lesley Jackson ; tõlk. Kai Lobjakas

    Index Scriptorium Estoniae

    Jackson, Lesley

    2006-01-01

    Inglise disainiajaloolane, auhinnažürii liige Eesti Tarbekunsti- ja Disainimuuseumis avatud IV Tallinna rakenduskunsti triennaalist "Kaks lähedast" ja preemia saanud töödest. Näituse kujundus: 3+1 Arhitektid. I preemia: Kersti Laanmaa ja Tiit Rammuli (rühmitus Muki) töö "Loomaarmastus", kaks teist preemiat: Piret Valk "Maa vägi", Caro Bärtling "Salvrätt-kraed"

  16. Kaval skeem abiraha paisutamiseks / Kristina Traks

    Index Scriptorium Estoniae

    Traks, Kristina, 1976-

    2006-01-01

    Ilmunud ka: Delovõje Vedomosti 12. apr. lk. 7. Erinevaid firmasid kasutades on ettevõtjad Prits Liblik ja Johannes Valk saanud ühe ja sama investeeringu jaoks toetust mitmel korral. Vt. samas: Kolm-ühes sigalakompleks Saaremaal teenis ära kolm investeeringutoetust; Viis eri firmat ostab seadmeid samasse tootmisse; Rakvere Lihakombinaadi tütar EKSEKO seafarm võrdsemate hulka ei mahtunud

  17. Arhitektuur rahu toomas / Triin Ojari

    Index Scriptorium Estoniae

    Ojari, Triin, 1974-

    2008-01-01

    Näitus "Identiteet ja arhitektuur [post-]konfliktsetes piirkondades" ("Peacebuilding") 30. okt.-9. nov. 2008 Casa dell' Architetturas Roomas. Üldkuraator Pippo Ciorra. Näitus keskendus Euroopa idaosa, Balkanimaade ja Lähis-Ida regioonile. Eestist oli näitusele valitud 7 objekti, autoriteks bürood Kolm Pluss Üks, KOKO Arhitektid, Kavakava, arhitektid Pekka Vapaavuori, Siiri Vallner, Indrek Peil, Tomomi Hayashi, Veronika Valk ja Aili Vahtrapuu

  18. Büroo ADM Interactive = Office ADM Interactive

    Index Scriptorium Estoniae

    2011-01-01

    Eesti Sisearhitektide Liidu 2010. a. ühiskondliku interjööri preemia pälvinud ADM Interactive'i büroost Tallinnas Rotermanni 8. Sisekujunduse autorid: arhitekt Tomomi Hayashi (HG Arhitektuur), sisearhitektid Ahti Grünberg (CadStudio OÜ) ja Kerli Valk (Kukuhaus OÜ), loetletud nende töid. Laelambid valmisid sisekujundajate jooniste järgi Hansanovas

  19. Eesti parim väikeehitis asub Võrumaal Lasval / Tiina Kolk

    Index Scriptorium Estoniae

    Kolk, Tiina

    2010-01-01

    Eesti Arhitektide Liidu konkursi "Väike 2007-2009" parimaks arhitektuuriliseks väikeobjektiks nimetati Lasva veetorn-galerii (Veronika Valk) Võrumaal, II preemia said Tallinna Tehnikaülikooli esisele väljakule paigaldatud pinkide eest Martin Pärn ja Edina Dufala-Pärn, III preemia läks aiamajale (Toomas Tammis, Paco Ulman) Meriväljal. Parimate väikevormide väljapanek Arhitektuuri- ja Disainigaleriis 19. juunini 2010

  20. 19.-25. IX toimub Rüütelkonna hoones Kumu pärlite nädal...

    Index Scriptorium Estoniae

    2005-01-01

    23. IX kõneleb Anu Allikvee teemal "Eestlane baltisaksa kunstnike vaatepiiris"; 24. IX tutvustab Mai Levin Eugen Dückeri maale, 25. IX Ene Lamp Konrad Mäge. Vt. ka lk. 24 Tähtede nädal 26. IX-2. X - kohtumisõhtutel esinevad Marika ja Heinz Valk, Jüri Kuuskemaa, Sirje Helme, Pekka Vapaavuori, Inge Teder, Rain Lõhmus

  1. Konkurss "Eesti kingitus"

    Index Scriptorium Estoniae

    2003-01-01

    Eesti Kodutöönduse Edendamise Keskseltsi ja Tallinna Ettevõtlusameti korraldatud konkursi "Eesti kingitus" žürii koosseis, tulemused. Peaauhinnad: I - Christi Kütt, II - Maaja Kalle, Ivar Jõgega, Valve Alamaa, III - Mauri Gross. Raekoja keldris avatud näituse kujundas Ene Ammer. Konkursi tulemusi kommenteerivad L. Soova, H. Valk, A. Raud, A. Kreem, L. Veskimägi

  2. Miks köögiviljakuningad ei taha ühineda? / Silja Lättemäe

    Index Scriptorium Estoniae

    Lättemäe, Silja, 1952-

    2006-01-01

    Euroopa Liit hüvitab osaliselt ühistegevuse kulud köögiviljasektoris. Eesti köögiviljakasvatajatel ei ole õnnestunud oma tootjaorganisatsiooni luua. Eesti juhtivad köögiviljatootjad on Ants Pak Kadarbiku talust, Kalle Reiter Agro AS-ist ja Johannes Valk Laheotsa talust. Vt. ka: Juur- ja köögiviljade eksport Eestist 2005. a jaanuar-oktoober

  3. Kommivabriku aura jääb Tondile. Ideid Kalevi kvartali tulevikuks / Piret Peensoo

    Index Scriptorium Estoniae

    Peensoo, Piret

    2003-01-01

    Tallinnas Järvevana tee ja Pärnu maantee vahelise ala ruumilise planeerimise ideeprojekti avalik arhitektuurikonkurss, võitjad Nikolai Volkov ja Liis Sagadi, 2. koht - Irina Raud, Toomas Tammis, Tarmo Teedumäe, Karl Luik, Renee Puusepp, 3. koht - Veronika Valk. Laste Maailma Galeriis võistlusprojektide näitus "Magus urbanism". Fakte kommivabriku "Kalev" ajaloost. Vabrik jätkab tööd Rae vallas Põrguväljal

  4. Kommivabriku aura jääb Tondile. Ideid Kalevi kvartali tulevikuks / Piret Peensoo

    Index Scriptorium Estoniae

    Peensoo, Piret

    2003-01-01

    Tallinnas Järvevana tee ja Pärnu maantee vahelise ala ruumilise planeerimise ideeprojekti avalik arhitektuurikonkurss, võitjad Nikolai Volkov ja Liis Sagadi, 2. koht - Irina Raud, Toomas Tammis, Tarmo Teedumäe, Karl Luik, Renee Puusepp, 3. koht - Veronika Valk. Laste Maailma Galeriis võistlusprojektide näitus "Magus urbanism". Fakte kommivabriku "Kalev" ajaloost. Vabrik jätkab tööd Rae vallas Põrguväljal

  5. Dolgaja doroga k hramu / Jekaterina Rodina

    Index Scriptorium Estoniae

    Rodina, Jekaterina

    2005-01-01

    Lasnamäe õigeusukiriku arhitektuurikonkursist ja võitnud töödest. Võitis Z-Projekti töö "Nikol", autorid arhitekt Oleg Zhemtshugov ning tema Minski kolleegid Nikolai Djatko ja Jevgeni Kolomenkin. Ergutuspreemiad said Veronika Valk ja Yoko Alender (OÜ ZiZi&YoYo) ning Jüri Martson, Rasmus Reinolt ja Ivo-Martin Veelma (AB Lokomotiiv OÜ). Žürii koosseis

  6. Sadamaala konkurss : Tallinna kesklinnaga piirneva mereäärse ala parima linnaehitusliku kontseptsiooni saamiseks korraldatud arhitektuurivõistlus / Andres Alver, Margus Koot, Arvo Rikkinen...[jt.] ; interv. Triin Ojari

    Index Scriptorium Estoniae

    2000-01-01

    Zürii liikmed konkursist, premeeritud töödest. Preemiad: I - Villem Tomiste, Veronika Valk; II - Illimar Truverk, Indrek Järve, Mattias Agabus, Tiit Sild, Karri Tiigisoon ning Toomas Paaver, Lauri Saar; III - Ivar Lubjak, Maria Pukk; ostud: Ott Kadarik, Rene Valner ning Siiri Vallner, Indrek Peil; täiendav ost (Muinsuskaitseamaet): Nikolai Serebrjakov, Leonid Tozil, Sergei Sevtsenko, Sulev Roosmaa. 6 illustratsiooni

  7. Arhitektuur rahu toomas / Triin Ojari

    Index Scriptorium Estoniae

    Ojari, Triin, 1974-

    2008-01-01

    Näitus "Identiteet ja arhitektuur [post-]konfliktsetes piirkondades" ("Peacebuilding") 30. okt.-9. nov. 2008 Casa dell' Architetturas Roomas. Üldkuraator Pippo Ciorra. Näitus keskendus Euroopa idaosa, Balkanimaade ja Lähis-Ida regioonile. Eestist oli näitusele valitud 7 objekti, autoriteks bürood Kolm Pluss Üks, KOKO Arhitektid, Kavakava, arhitektid Pekka Vapaavuori, Siiri Vallner, Indrek Peil, Tomomi Hayashi, Veronika Valk ja Aili Vahtrapuu

  8. ONR Tokyo Scientific Bulletin. Volume 2, Number 2. April-June 1977,

    Science.gov (United States)

    1977-01-01

    authors were l)r. I lideshige lmai , Albany Medical (‘ollege , Albany, New York: I)rs. Albert I I . Sub way and V . Subramanyam , Northeastern...and already iu ~ operatio n . It occupies 245 hee t ares ( abou t 600 acres) of the n e w town. By Japanese s tamidards such a camu ipu s vt

  9. 同轴电缆通信与光通信

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    0612162 以太网无源光网络中动态带宽分配算法=Dynamic bandwidth allocation alorithm in ethernet passive optical networks[刊,英]/Hee-Jung Byun,Ji-Myung Nho//Electronics letters.-2003,39(13).-1001(E)

  10. Acupuncture laser in treating headache pain

    Science.gov (United States)

    Smesny, Dunja B.

    1990-09-01

    Cervicoocipital headache observed in 112 patient were treated, half of them with acupuncture, and other 50% with He-e laser (con tinuous emission- lo mW, 633nm: IEC). With this treatment was also combined an exercise program ne cesary for the mobilisation of functionaly blocked vertebral segment.

  11. Breast Cancer Gene Therapy: Development of Novel Non-Invasive Magnetic Resonance Assay to Optimize Efficacy

    Science.gov (United States)

    2007-05-01

    86, 88, 89], isolated hepatocytes [90], rabbit colon and frog skin [86]. Thoma and Ugurbil [91] used this approach in a perfused liver. Comparison...Reson. Med. 1993, 29, 446-458. [253] P. S. Hees and C. H. Sotak, Assessment of changes in murine tumor oxygenation in response to nicotinamide using

  12. The impact of health economic evaluations in Sweden.

    Science.gov (United States)

    Heintz, Emelie; Arnberg, Karl; Levin, Lars-Åke; Liliemark, Jan; Davidson, Thomas

    2014-01-01

    The responsibility for healthcare in Sweden is shared by the central government, county councils and municipalities. The counties and municipalities are free to make their own prioritizations within the framework of the state healthcare laws. To guide prioritization of healthcare resources in Sweden, there is consensus that cost-effectiveness constitutes one of the three principles. The objective of this paper is to describe how cost-effectiveness, and hence health economic evaluations (HEE), have a role in pricing decisions, reimbursement of pharmaceuticals as well as the overall prioritization and allocation of resources in the Swedish healthcare system. There are various organizations involved in the processes of implementing health technologies in the Swedish healthcare system, several of which consider or produce HEEs when assessing different technologies: the Dental and Pharmaceutical Benefits Agency (TLV), the county councils' group on new drug therapies (NLT), the National Board of Health and Welfare, the Swedish Council on Health Technology Assessment (SBU), regional HTA agencies and the Public Health Agency of Sweden. The only governmental agency that has official and mandatory guidelines for how to perform HEE is TLV (LFNAR 2003:2). Even though HEEs may seem to have a clear and explicit role in the decision-making processes in the Swedish healthcare system, there are various obstacles and challenges in the use and dissemination of the results.

  13. Holographic entanglement entropy in 2D holographic superconductor via AdS3/CFT2

    Directory of Open Access Journals (Sweden)

    Davood Momeni

    2015-07-01

    Full Text Available The aim of the present letter is to find the holographic entanglement entropy (HEE in 2D holographic superconductors (HSC. Indeed, it is possible to compute the exact form of this entropy due to an advantage of approximate solutions inside normal and superconducting phases with backreactions. By making the UV and IR limits applied to the integrals, an approximate expression for HEE is obtained. In case the software cannot calculate minimal surface integrals analytically, it offers the possibility to proceed with a numerical evaluation of the corresponding terms. We'll understand how the area formula incorporates the structure of the domain wall approximation. We see that HEE changes linearly with belt angle. It's due to the extensivity of this type of entropy and the emergent of an entropic force. We find that the wider belt angle corresponds to a larger holographic surface. Another remarkable observation is that no “confinement/deconfinement” phase transition point exists in our 2D dual field theory. Furthermore, we observe that the slope of the HEE with respect to the temperature dSdT decreases, thanks to the emergence extra degree of freedom(s in low temperature system. A first order phase transition is detected near the critical point.

  14. Jürgen Jaspers: De klank van de stad. Stedelijke meertaligheid en interculturele communicatie (red.). Leuven, ACCO, 2009. 219 blz.

    NARCIS (Netherlands)

    Nortier, J.M.

    2010-01-01

    De klank van de stad is geschreven naar aanleiding van een congres over hetzelfde thema, stedelijke meertaligheid (maart 2008, Antwerpen). De auteurs waren in meerderheid sprekers bij het congres die hun presentaties in soms wat gewijzigde vorm hebben opgeschreven. Iedereen die wel eens te maken hee

  15. Iron-Deficiency Anemia

    Medline Plus

    Full Text Available ... a lower than normal number of red blood cells. Red blood cells carry oxygen and remove carbon dioxide (a waste ... Anemia also can occur if your red blood cells don't contain enough hemoglobin (HEE-muh-glow- ...

  16. Iron-Deficiency Anemia

    Medline Plus

    Full Text Available ... a lower than normal number of red blood cells. Red blood cells carry oxygen and remove carbon dioxide (a waste ... Anemia also can occur if your red blood cells don't contain enough hemoglobin (HEE-muh-glow- ...

  17. Inhibition of human dendritic cell activation by hydroethanolic but not lipophilic extracts of turmeric (Curcuma longa).

    Science.gov (United States)

    Krasovsky, Joseph; Chang, David H; Deng, Gary; Yeung, Simon; Lee, Mavis; Leung, Ping Chung; Cunningham-Rundles, Susanna; Cassileth, Barrie; Dhodapkar, Madhav V

    2009-03-01

    Turmeric has been extensively utilized in Indian and Chinese medicine for its immune-modulatory properties. Dendritic cells (DCs) are antigen-presenting cells specialized to initiate and regulate immunity. The ability of DCs to initiate immunity is linked to their activation status. The effects of turmeric on human DCs have not been studied. Here we show that hydroethanolic (HEE) but not lipophilic "supercritical" extraction (SCE) of turmeric inhibits the activation of human DCs in response to inflammatory cytokines. Treatment of DCs with HEE also inhibits the ability of DCs to stimulate the mixed lymphocyte reaction (MLR). Importantly, the lipophilic fraction does not synergize with the hydroethanolic fraction for the ability of inhibiting DC maturation. Rather, culturing of DCs with the combination of HEE and SCE leads to partial abrogation of the effects of HEE on the MLR initiated by DCs. These data provide a mechanism for the anti-inflammatory properties of turmeric. However, they suggest that these extracts are not synergistic and may contain components with mutually antagonistic effects on human DCs. Harnessing the immune effects of turmeric may benefit from specifically targeting the active fractions.

  18. Review Essay: Governmentality in Late Colonial Korea?

    Directory of Open Access Journals (Sweden)

    Henry Em

    2012-12-01

    Full Text Available Takashi Fujitani, Race for Empire: Koreans as Japanese and Japanese as Americans during World War II. Berkeley: University of California Press, 2011. 520 pp. $65 (cloth.Jun Uchida, Brokers of Empire: Japanese Settler Colonialism in Korea, 1876-1945. Cambridge, MA: Harvard University Press, 2011. 500 pp. $50 (cloth.In South Korea, more so than in most other postcolonial countries, the issue of sovereignty and the colonial past remains a central feature of politics. Most recently, during a televised presidential debate on December 4, 2012, Lee Jung-hee of the Unified Progressive Party said something that likely had never been said on South Korean television: “Takaki Masao signed an oath of loyalty [to the Emperor of Japan], in his own blood, to become an officer in the Japanese [Imperial] Army. You know who he is. His Korean name is Park Chung Hee.” Lee Jung-hee then made the connection between that colonial past and the willingness to sell out the nation’s sovereignty in the present. The conservative candidate Park Geun-hye, the daughter of the late President Park Chung Hee who ruled South Korea from 1961 through 1979, and members of Park’s Saenuri Party, remain true to their “roots”: these “descendants of pro-Japanese collaborators and dictators” (again sold out South Korea’s sovereignty (on November 22, 2011 when they rammed the US-ROK Free Trade Agreement through the National Assembly.

  19. Voedingswetenschapper overleden : in memoriam Ancel Keys

    NARCIS (Netherlands)

    Kromhout, D.; Katan, M.B.

    2005-01-01

    Op 20 november 2004 stierf in Minneapolis Ancel Keys, een van de grootste onderzoekers op het gebied van voeding en hart- en vaatziekten van de 20e eeuw. Keys is bekend geworden door zijn voedingsexperimenten naar de relatie tussen vetzuren en serumcholesterol en door de Zeven Landen Studie. Hij hee

  20. Langjarige trends in aantallen wadvogels, in relatie tot de kokkelvisserij en het gevoerde beleid in deze; eindverslag EVA II (evaluatie schelpdiervisserij tweede fase) deelproject C2

    NARCIS (Netherlands)

    Leopold, M.F.; Smit, C.J.; Goedhart, P.W.; Roomen, van M.W.J.; Winden, van A.J.; Turnhout, van C.

    2004-01-01

    Dit rapport beschrijft een analyse van de resultaten van circa 30 jaar hoogwater-vogeltellingen in de Waddenzee, tegen de achtergrond van de mechanische kokkelvisserij in dit gebied en het gevoerde beleid in deze, met name het sluiten van grote gebieden voor deze visserij in 1993. Deze maatregel hee

  1. Rh Incompatibility

    Science.gov (United States)

    ... attack the baby's red blood cells. This can lead to hemolytic anemia (HEE-moh-lit-ick uh-NEE-me-uh) ... baby won't get enough oxygen. This can lead to serious problems. Severe hemolytic anemia may even be fatal to the child. Outlook ...

  2. Do plants drive podzolization via rock-eating mycorrhizal fungi?

    NARCIS (Netherlands)

    Breemen, van N.; Lundstr"m, U.S.; Jongmans, A.G.

    2000-01-01

    Weathering and supply of nutrients derived from minerals to plants is known to be stimulated by plant symbiotic mycorrhizal fungi. Nutrients are generally thought to pass the bulk soil solution before plant uptake. Jongmans et al. [Jongmans, A.G., van Breemen, N., Lundstrom, U.S., van Hees, P.A.W.,

  3. Internet gedreven innoveren vergroot veiligheid

    NARCIS (Netherlands)

    Beijer, P. de

    2013-01-01

    De overheid kan veel, heel veel leren van het Internet. Het hee2 namelijk een aantal zeer aantrekkelijke karakter eigenschappen (open, anarchistisch, snel, grenzeloos, plat georganiseerd) die overheden traditioneel onvoldoende hebben maar die wel enorm kunnen helpen succesvol te innoveren. Successen

  4. Open chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function.

    Science.gov (United States)

    Browne, James A; Yang, Rui; Song, Lingyun; Crawford, Gregory E; Leir, Shih-Hsing; Harris, Ann

    2014-12-01

    The epithelium lining the epididymis in the male reproductive tract maintains a luminal environment that promotes sperm cell maturation. This process is dependent on the coordinated expression of many genes that encode proteins with a role in epithelial transport. We previously generated genome-wide maps of open chromatin in primary human epididymis epithelial (HEE) cells to identify potential regulatory elements controlling coordinated gene expression in the epididymis epithelium. Subsequent in silico analysis identified transcription factor-binding sites (TFBS) that were over-represented in the HEE open chromatin, including the motif for paired box 2 (PAX2). PAX2 is a critical transcriptional regulator of urogenital tract development, which has been well studied in the kidney but is unexplored in the epididymis. Due to the limited lifespan of primary HEE cells in culture, we investigated the role of PAX2 in an immortalized HEE cell line (REP). First, REP cells were evaluated by DNase I digestion followed by high-throughput sequencing and the PAX2-binding motif was again identified as an over-represented TFBS within intergenic open chromatin, though on fewer chromosomes than in the primary HEE cells. To identify PAX2-target genes in REP cells, RNA-seq analysis was performed after siRNA-mediated depletion of PAX2 and compared with that with a non-targeting siRNA. In response to PAX2-repression, 3135 transcripts were differentially expressed (1333 up-regulated and 1802 down-regulated). Novel PAX2 targets included multiple genes encoding proteins with predicted functions in the epididymis epithelium.

  5. Enhanced horizontal extreme-echo speed occurrence leading to polar mesospheric summer echoes (PMSE) increase at solar-wind pressure enhancement during high-speed solar wind stream events

    Science.gov (United States)

    Lee, Y.; Kirkwood, S.; Kwak, Y.; Kim, K.; Shepherd, G. G.

    2013-12-01

    We report on horizontal extreme echo speeds (HEES, ≥ 300 ms^{-1}) observed in long-periodic polar mesospheric summer echoes (PMSE) correlated with solar-wind speed in high speed solar wind streams (HSS) events. The observations were made from VHF 52 MHz radar measurements at Esrange (67.8°N, 20.4°E) between June 1-August 8 in 2006 and 2008. The periodicities of PMSE counts and the volume reflectivity primarily occur at 7, 9 and 13.5 days possibly by the effects of HSS, while the periodicities at 4-6 days are competitively coherent between planetary waves appearing in temperature and solar-wind speed during HSS events. The peaks of both HEES occurrence rate relative to PMSE and turbulence dominantly occur at solar-wind pressure enhancement with minor peaks continued under the passage of HSS over the magnetopause, followed by PMSE peaks in 1-3 days later. This study gives the results that the precipitating high-energetic particles (> 30 keV) during HSS likely induce D-region ionization involved with the consecutive processes of HEES, turbulence and PMSE. The turbulence evolved from the HEES can be explained with the Kelvin-Helmholtz instability, which was observed in PMSE by Röttger et al. [11th International Workshop on technical and scientific aspects of MST Radar, 2006] and firstly simulated for PMSE generation by Hill et al. [Earth Planets Space, 1999]. The HEES is understood as the speed of fast moving ions, accelerated by strong electric field as Lee & Shepherd [JGR, 2010] suggested with the supersonic velocities persisting in polar mesospheric clouds (PMC) region observed at enhanced O(^1S) emission rate ( 10 kR) by WINDII/UARS satellite.

  6. Israelische Public Diplomacy und ihre Wahrnehmung durch deutsche Journalisten

    Directory of Open Access Journals (Sweden)

    Florian Fleischer

    2014-07-01

    Full Text Available Public Diplomacy stellt insbesondere für Staaten in internationalen Konflikten wie Israel ein wichtiges Kommunikationsinstrument dar, um ausländische Bevölkerungen zu erreichen. Der Artikel zeigt die Ergebnisse einer Studie, in der untersucht wurde, wie die israelische Public Diplomacy von deutschen Journalisten aufgenommen und verarbeitet wird. Journalisten kommt dabei eine Schlüsselrolle als Mittler zwischen dem israelischen Staat und der deutschen Bevölkerung zu. In Anlehnung an den Katalog der Public Diplomacy-Maßnahmen von Gilboa (2006 wurde die Relevanz einzelner Maßnahmen für Journalisten erfragt. Die Ergebnisse zeigen, dass persönliche Kontakte für Journalisten nach wie vor eine wichtige Quelle darstellen und nicht von Cyber-Public Diplomacy ersetzt werden können. Staatliche Public Diplomacy wird zwar wahrgenommen, jedoch wird ihre Objektivität bezweifelt, während NGOs und Stiftungen als vertrauenswürdiger eingestuft werden. Des Weiteren wird Israel in der Öffentlichkeit nach wie vor dominierend mit dem Nahostkonflikt identifiziert, was sich nach Meinung der befragten Journalisten auch in Zukunft nicht durch gezielte Öffentlichkeitsarbeit verhindern lässt.

  7. FOREIGN AND DOMESTIC EXPERIENCE OF INTEGRATING CLOUD COMPUTING INTO PEDAGOGICAL PROCESS OF HIGHER EDUCATIONAL ESTABLISHMENTS

    Directory of Open Access Journals (Sweden)

    Nataliia A. Khmil

    2016-01-01

    Full Text Available In the present article foreign and domestic experience of integrating cloud computing into pedagogical process of higher educational establishments (H.E.E. has been generalized. It has been stated that nowadays a lot of educational services are hosted in the cloud, e.g. infrastructure as a service (IaaS, platform as a service (PaaS and software as a service (SaaS. The peculiarities of implementing cloud technologies by H.E.E. in Ukraine and abroad have been singled out; the products developed by the leading IT companies for using cloud computing in higher education system, such as Microsoft for Education, Google Apps for Education and Amazon AWS Educate have been reviewed. The examples of concrete types, methods and forms of learning and research work based on cloud services have been provided.

  8. Nuevo yacimiento de flora Albense en la vertiente sur de la Sierra de Guadarrama. Soto del Real (Madrid)

    OpenAIRE

    1986-01-01

    A new superior Albian - Cenomanian fossil flore locality are described for the first time on. the Sierra Guadarrama (Madrid). Between all the numerous specimens there found. stand out, due to their abundancy, the ones belonging to various species of Cycadales and Coniferals, accompanied by the Filicales, Lycopodiales and the Angiosperms Monocotiledonae and Dicotilodenae of the Policarpicales and Rosales orders. Two species of the Filicales orderGleichenites giesekianus (Hee...

  9. Holographic Entanglement Entropy, Field Redefinition Invariance and Higher Derivative Gravity Theories

    CERN Document Server

    Mozaffar, M R Mohammadi; Sheikh-Jabbari, M M; Vahidinia, M H

    2016-01-01

    It is established that physical observables in local quantum field theories should be invariant under invertible field redefinitions. It is then expected that this statement should be true for the entanglement entropy and moreover that, via the gauge/gravity correspondence, the recipe for computing entanglement entropy holographically should also be invariant under field redefinitions in the gravity side. We use this fact to fix the recipe for computing holographic entanglement entropy (HEE) for $f(R,R_{\\mu\

  10. The Korean Question--Revisited.

    Science.gov (United States)

    1987-03-01

    8 Mutual Defense Treaty ..............: 11 Nixon Doctrine .. .. .. . .. ... .. .. .. ... 12 Cate’ Policy .................... 13 III KOREA AND U.S...cited Melvin Laird, former Republican Secretary of Defense (1969-73) and Korean President (1961-1979) Park Chung Hee.1 The 1972 presidential candidate...rights and the ability of South Korea to defend itself, to displeasure over inequity of the defense burden, to the real concern over the possibility of

  11. Layer by Layer Growth of 2D Quantum Superlattices (NBIT III)

    Science.gov (United States)

    2017-02-28

    AFRL-AFOSR-JP-TR-2017-0019 Layer-by-Layer Growth of 2D Quantum Superlattices (NBIT III) Jiwoong Park CORNELL UNIVERSITY Final Report 02/22/2017...NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) CORNELL UNIVERSITY 373 PINE TREE RD ITHACA, NY 14850-2820 US 8. PERFORMING ORGANIZATION...age) Hee Cheul Choi (44) Full Name (age) Jiwoong Park (41) Nationality Korea Nationality Korea (US Resident ) Affiliation (department) POSTECH

  12. The 2H(e, e' p)n reaction at large energy transfers

    NARCIS (Netherlands)

    Willering, Hendrik Willem

    2003-01-01

    At the ELSA accelerator facillity in Bonn, Germany, we have measured the deutron "breakup" reaction 2H(e,e' p)n at four-momentum transfers around Q2 = -0 .20(GeV/c)2 with an electron beam energy of E0 = 1.6 GeV. The cross section has been determined for energy transfers extending from the quasielast

  13. Statistical Inference on Memory Structure of Processes and Its Applications to Information Theory

    Science.gov (United States)

    2016-05-12

    scholarships or fellowships for further studies in science, mathematics, engineering or technology fields: Student Metrics This section only applies to...and provides 9- month salaries. They get summer support from the department after they have passed the qualifying exams . By the summer of 2014, Hee...Sun Kim had not passed the exams yet but she was prepared to give up her scientific career because her family suddenly lost all income. The grant

  14. On Tradeoffs between Trust and Survivability using a Game Theoretic Approach

    Science.gov (United States)

    2016-04-13

    networks. In: Pro . 6th Annual ACM/IEEE Mobile Computing and Networking, pp.255- 265, Boston, MA (Aug. 2000) 14. Ng, S.K., Seah, W.K.G.: Game ...On Tradeoffs between Trust and Survivability using a Game Theoretic Approach Jin-Hee Cho and Ananthram Swami U.S. Army Research Laboratory...introduces a game theoretic approach, namely Aoyagi’s game theory based on positive collusion of players. This approach improves group trust by

  15. Metabolic Signaling and Therapy of Lung Cancer

    Science.gov (United States)

    2013-09-01

    Changliang Shan,1 Qing Dai,4 Liang Zhang,4 Jianxin Xie,5 Ting-Lei Gu,5 Peng Jin,2 Masa Aleckovic,6 Gary LeRoy,6 Yibin Kang,6 Jessica A. Sudderth,7...Liang Zhang2, Jianxin Xie3, Yi Wang3, Ting-Lei Gu3, Masa Alečković4, Gary LeRoy4, Yibin Kang4, Hee-Bum Kang 1, Jae-Ho Seo1, Changliang Shan1, Peng Jin5

  16. Antinuclear movement

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Young Hee; Im, Jaeg Yeong

    1988-08-15

    This book is for antinuclear movement. So, this book introduces many articles on nuclear issues of Asia and the pacific area. The titles of articles are the crusades of Reagan by Werner Plaha, contending between super powers in Europe by Alva Reimer Myrdal, claims of resistance by Daniel Ellsberg, nuclear and the Korean Peninsula by Go, Seung Woo, Liberation but of belief of nuclear weapon by Lee, Young Hee and nuclear weapon in Korea by peter Haze.

  17. Vormistatud ruumid 2010 / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    2011-01-01

    Eesti Sisearhitektide Liidu 2010. a. preemia saanud töödest. Söögikoha interjööri preemia: kohvik Supelsaksad Pärnus (Ruth, Jaak ja Anna Huimerind), ühiskondliku interjööri preemia: ADM Interactive'i büroo Tallinnas (Tomomi Hayashi, Ahti Grünberg, Kerli Valk), ajaloolise interjööri preemia: Kihnu muuseum (Malle Jürgenson, Tea Tammelaan, Krista Lepland, Jaak Huimerind, Indrek Laos), näituse- ja installatsiooni kujunduse preemia: rändnäitus "Eesti kirjanik karikatuuris" (Janno Siimar, Kaarel Vahtramäe, Mart Lankots, Liina Jakobson), tudengipreemia - Aet Tera

  18. Parimad interjöörid: büroo, külamuuseum ja kohvik / Tiina Kolk

    Index Scriptorium Estoniae

    Kolk, Tiina

    2011-01-01

    Eesti Sisearhitektide Liit valis 2010. aasta parimad interjöörid: kohvik Supelsaksad Pärnus (Anna ja Ruth Huimerind), ADM Interactive'i bürooruumid Tallinnas (Tomomi Hayashi, Ahti Grünberg, Kerli Valk), Kihnu muuseum (Malle Jürgenson, Tea Tammelaan, Krista Lepland, Jaak Huimerind, Indrek Laos). Näituse ja installatsiooni kujunduse preemia pälvis rändnäitus "Eesti kirjanik karikatuuris" (Janno Siimar, Kaarel Vahtramäe, Mart Lankots, Liina Jakobson). Tudengipreemia pälvis Aet Tera. Nominentide tööde põhjal avati 17. mail 2011 Arhitektuuri- ja Disanigaleriis näitus

  19. Elagu manhattaniseerumine! = Long Live Manhattanisation! / Panu Lehtovuori

    Index Scriptorium Estoniae

    Lehtovuori, Panu, 1968-

    2006-01-01

    Maakri kvartali arhitektuurikonkursist. Võistlustööd vajavad veel edasist läbitöötamist ja seetõttu on vajalik võistluse II etapp. Töödest "Galileo", autorid Tõnu Laigu, Koit Ojaliiv, Juhan Rohtla (QP Arhitektid), "Urban Village", autor Kalle Komissarov, "Parkour'32", autorid Kadri Tamre, Indrek Tiigi, Ülar Mark (Urban Mark), "Parabool", autorid Leena Torim, Veronika Valk, Tõnis Arjus, Kadri Klementi, Eerik Kändler (Zizi & Yoyo), "Trident", autorid Ott Kadarik, Villem Tomiste, Mihkel Tüür (Kosmos)

  20. Eesti Kunstnike Liidu volikogu

    Index Scriptorium Estoniae

    2003-01-01

    Koosolek 16. XII 2002. a. Kinnitati Tallinna Kunstihoone, selle galerii ja Linnagalerii 2003. a. näituste plaan. Hobusepea galerii galerist on E. Kard. EKLi auliikmeteks valiti E. Viies, L. Viiroja, O. Terri, V. Väli, S. Raunam, A. Mölder, M.-L. Küla, E. Renter. 20. XII tähistati Kunstihoones Eesti Kujutavate Kunstnikkude Keskühingu 80. aastapäeva (näituse koostas J. Kivimäe), esitleti EKLi 2000. ja 2001. a. aastaraamatut (koostaja L. Siib, kujundaja M. Valk)

  1. Elagu manhattaniseerumine! = Long Live Manhattanisation! / Panu Lehtovuori

    Index Scriptorium Estoniae

    Lehtovuori, Panu, 1968-

    2006-01-01

    Maakri kvartali arhitektuurikonkursist. Võistlustööd vajavad veel edasist läbitöötamist ja seetõttu on vajalik võistluse II etapp. Töödest "Galileo", autorid Tõnu Laigu, Koit Ojaliiv, Juhan Rohtla (QP Arhitektid), "Urban Village", autor Kalle Komissarov, "Parkour'32", autorid Kadri Tamre, Indrek Tiigi, Ülar Mark (Urban Mark), "Parabool", autorid Leena Torim, Veronika Valk, Tõnis Arjus, Kadri Klementi, Eerik Kändler (Zizi & Yoyo), "Trident", autorid Ott Kadarik, Villem Tomiste, Mihkel Tüür (Kosmos)

  2. Kultuurkapitali aastapreemiad 2009 / Liina Jänes

    Index Scriptorium Estoniae

    Jänes, Liina, 1977-

    2010-01-01

    Žürii liige kandidaatidest, preemia saanud objektidest, preemia määramise põhjendus. Peapreemia said Andres Alver, Veljo Kaasik ja Tiit Trummal Tallinna Vabaduse väljaku eest. Arhitektuuri objektipreemia võitis Uus- ja Vana Jahuladu Tallinnas (HG Arhitektuur, Hanno Grossschmidt, Tomomi Hayashi, Yoko Azukava), väikeobjekti preemia Lasva veetorn (põhiautor Veronika Valk), restaureerimise preemia Nõmme Saksa Lunastaja kirik (Fredi-Armand Tomps, Anne Koppel), sisearhitektuuri preemia AS Baltika büroo (Studio 3, Kolm Pluss Üks), tegevuspreemia Ilona Gurjanova

  3. Eesti Kunstnike Liidu volikogu

    Index Scriptorium Estoniae

    2003-01-01

    Koosolek 16. XII 2002. a. Kinnitati Tallinna Kunstihoone, selle galerii ja Linnagalerii 2003. a. näituste plaan. Hobusepea galerii galerist on E. Kard. EKLi auliikmeteks valiti E. Viies, L. Viiroja, O. Terri, V. Väli, S. Raunam, A. Mölder, M.-L. Küla, E. Renter. 20. XII tähistati Kunstihoones Eesti Kujutavate Kunstnikkude Keskühingu 80. aastapäeva (näituse koostas J. Kivimäe), esitleti EKLi 2000. ja 2001. a. aastaraamatut (koostaja L. Siib, kujundaja M. Valk)

  4. Eesti graafika rahvusvahelistel näitustel

    Index Scriptorium Estoniae

    2003-01-01

    Inga Heamägi ja Benjamin Vasserman osalevad 3. X-4. XII Bangkokis rahvusvahelisel graafika ja joonistuste näitusel "Interprint". Peapreemia - Katarina Vavrova Slovakkiast. 2003. a. Krakovi graafikatriennaalil pälvis peapreemia Davida Kidd Kanadast, aupeapreemia Toshihiro Hamano Jaapanist, Saksa panga preemia Eve Kask, Eestist osalevad näitusel I. Heamägi, Avo Keerend, Silvi Liiva, Ülle Marks ja Jüri Kass, Vive Tolli, Kelli Valk (Kagovere), B. Vasserman, näitusel "Intergrafia 2003" Niepolomice muuseumis osalevad Eestist A. Keerend, Peeter Laurits, Ü. Marks ja J. Kass, Andres Tali, V. Tolli, B. Vasserman, Vello Vinn

  5. Antioxidant Effect of Extracts from the Coffee Residue in Raw and Cooked Meat

    Directory of Open Access Journals (Sweden)

    Ji-Hee Kim

    2016-07-01

    Full Text Available The residue of ground coffee obtained after the brewing process (spent coffee still contains various functional components with high antioxidant capacity and health benefits, but no attempts have been made to use it as a resource to produce value-added food ingredients. This study evaluates the antioxidant activity of ethanol or hot water extracts from the residues of coffee after brewing. An extraction experiment was carried out using the conventional solid–liquid methods, including ethanol and water as the extraction media at different temperatures and liquid/solid ratios. The antioxidant activity of extracts was tested for total phenolic compound (TPC, 2,2-diphenyl-1-picrylhydrazyl (DPPH, and 2-thiobarbituric acid reactive substances (TBARS using oil emulsion and raw/cooked meat systems. The DPPH radical scavenging activity of the ethanol extracts with heating (HEE and without heating (CEE were higher than that of the hot water extracts (WE. The highest DPPH value of HEE and CEE at 1000 ppm was 91.22% and 90.21%, respectively. In oil emulsion and raw/cooked systems, both the water and ethanol extracts had similar antioxidant effects to the positive control (BHA, but HEE and CEE extracts showed stronger antioxidant activities than WE extract. These results indicated that the ethanol extracts of coffee residue have a strong antioxidant activity and have the potential to be used as a natural antioxidant in meat.

  6. Holographic entanglement entropies for Schwarzschild and Reisner-Nordstr\\"om spacetimes

    CERN Document Server

    Sun, Yuan

    2016-01-01

    The holographic entanglement entropies (HEE) associated with four dimensional Schwarzschild and Reisner-Nordstr\\"om spacetimes are investigated. Unlike the cases of asymptotically AdS spacetimes for which the boundaries are always taken at (timelike) conformal infinities, we take the boundaries at either large but finite radial coordinate (far boundary) or very close to the black hole event horizons (near horizon boundary). The reason for such choices is that such boundaries are similar to the conformal infinity of AdS spacetime in that they are all timelike, so that there may be some hope to define dual systems with ordinary time evolution on such boundaries. Our results indicate that, in the case of far boundaries, the leading order contribution to the HEEs come from the background Minkowski spacetime, however, the next to leading order contribution which arises from the presence of the black holes is always proportional to the black hole mass, which constitutes a version of the first law of the HEE for asy...

  7. Antioxidant Effect of Extracts from the Coffee Residue in Raw and Cooked Meat.

    Science.gov (United States)

    Kim, Ji-Hee; Ahn, Dong Uk; Eun, Jong Bang; Moon, Sun Hee

    2016-07-04

    The residue of ground coffee obtained after the brewing process (spent coffee) still contains various functional components with high antioxidant capacity and health benefits, but no attempts have been made to use it as a resource to produce value-added food ingredients. This study evaluates the antioxidant activity of ethanol or hot water extracts from the residues of coffee after brewing. An extraction experiment was carried out using the conventional solid-liquid methods, including ethanol and water as the extraction media at different temperatures and liquid/solid ratios. The antioxidant activity of extracts was tested for total phenolic compound (TPC), 2,2-diphenyl-1-picrylhydrazyl (DPPH), and 2-thiobarbituric acid reactive substances (TBARS) using oil emulsion and raw/cooked meat systems. The DPPH radical scavenging activity of the ethanol extracts with heating (HEE) and without heating (CEE) were higher than that of the hot water extracts (WE). The highest DPPH value of HEE and CEE at 1000 ppm was 91.22% and 90.21%, respectively. In oil emulsion and raw/cooked systems, both the water and ethanol extracts had similar antioxidant effects to the positive control (BHA), but HEE and CEE extracts showed stronger antioxidant activities than WE extract. These results indicated that the ethanol extracts of coffee residue have a strong antioxidant activity and have the potential to be used as a natural antioxidant in meat.

  8. Modeling and experiments to explain the potential dependency of an UHSS to hydrogen environment assisted cracking

    Science.gov (United States)

    Kehler, Beth A.

    Modern ultra high strength steels have been developed with outstanding combinations of strength and fracture toughness but lack intrinsic corrosion resistance. Such steels are used by the military for aircraft components such as landing gears but require coatings and cathodic protection which can lead to various rates of hydrogen production depending on material, geometry, and electro(chemistry). The susceptibility of such steels to internal hydrogen embrittlement (IHE) and hydrogen environment embrittlement (HEE) limits their use in marine environments. The objective of this research is to develop the understanding necessary to design coated ultra high strength steels that resist HEE when stressed in marine environments. The cause of HEE is the establishment of high diffusible hydrogen concentrations (CH,diff) at the crack tip. There is a window of applied potentials (Eapplied) where susceptibility to HEE is reduced because CH,diff is reduced. However, Eapplied itself does not yield insight as to the exact conditions at the crack tip. Ohmic potential drop and electrochemical/chemical reactions in the crack can lead to a significantly different environment at the crack tip than on the surface. The issues that hinder understanding of HEE center on the capability to quantify and ultimately predict crack tip hydrogen concentrations (C H,Tip) relative to critical concentrations that trigger fracture as a function of Eapplied. CH,tip was characterized using a multi-pronged approach. Scaling laws were developed to enable measurements of E and pH in a scaled-up crack as a function of the scaling parameter, x2/G and Eapplied . Such measurements were correlated with CH,diff using an experimentally determined hydrogen uptake law based on first order absorption laws and trapping theory. CH,diff values were then used as inputs into existing micromechanical models for KTH and da/dtII to predict cracking susceptibility. The scientific contributions of this work include the

  9. The effect of clove-based herbal mouthwash on radiation-induced oral mucositis in patients with head and neck cancer: a single-blind randomized preliminary study

    Directory of Open Access Journals (Sweden)

    Kong M

    2016-07-01

    Full Text Available Moonkyoo Kong,1 Deok-Sang Hwang,2 Seong Woo Yoon,3 Jinsung Kim4 1Department of Radiation Oncology, Kyung Hee University Medical Center, Kyung Hee University School of Medicine, 2Department of Korean Medicine Obstetrics & Gynecology, Kyung Hee University Medical Center, 3Department of Korean Internal Medicine, Korean Medicine Cancer Center, Kyung Hee University Hospital at Gangdong, 4Department of Korean Internal Medicine, Kyung Hee University Medical Center, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea Purpose: This study was performed to evaluate the efficacy and safety of clove-based herbal mouthwash in ameliorating radiation-induced oral mucositis in patients with head and neck cancer. Methods: Fourteen patients were prospectively enrolled in this study and randomized to either an experimental group or a control group. The patients of the experimental group swished their mouths with a clove-based herbal mouthwash during radiotherapy (RT, while the patients of the control group swished with clear water. The primary end point of this study was incidence of radiation-induced oral mucositis. The secondary end points were time to onset of radiation-induced oral mucositis, duration of radiation-induced oral mucositis, incidence of supplemental nutrition through feeding tube, maximum pain score, body weight loss, incidence of RT interruption, and duration of RT interruption. Results: The use of clove-based herbal mouthwash shortened the duration of grade ≥2 mucositis (24.3 days vs 37.1 days, P=0.044 and reduced body weight loss during RT (3.1% vs 7.4%, P=0.023 compared with clear water. The use of clove-based herbal mouthwash also reduced the incidence of grade 3 mucositis (28.6% vs 57.1%, supplemental nutrition (0% vs 28.6%, and RT interruption (14.3% vs 28.6%, and reduced the duration of grade 3 mucositis (5.1 days vs 17.7 days and RT interruption (1 days vs 8.5 days. In addition, clove-based herbal mouthwash

  10. Stevia rebaudiana Bertoni - chemical composition and functional properties.

    Science.gov (United States)

    Marcinek, Katarzyna; Krejpcio, Zbigniew

    2015-01-01

    Sweetleaf (Stevia rebaudiana Bertoni), currently investigated by many researchers, has been known and used for more than a thousand years indigenous tribes of South America, who called it "kaa-hee" ("sweet herb"). Thanks to its chemical composition and processability sweetleaf may be an alternative for synthetic sweeteners. Nutritional and health-promoting aspects of Stevia rebaudiana are presently being studied in many research centres. The aim of this study is to present nutritional and health-promoting value of the still-little known sweetleaf.

  11. Radiation Therapy of Pituitary Tumors

    Energy Technology Data Exchange (ETDEWEB)

    Park, Moon Baik; Hong, Seong Eong [Kyunghee University College of Medicine, Seoul (Korea, Republic of)

    1989-12-15

    Radiation treatment results were analyzed in a retrospective analysis of 47 patients with pituitary adenoma treated with radiation alone or combined with surgery from 1974 through 1987 at the Department of Therapeutic Radiology of Kyung Hee University. The 5-year overall survival rates for all patients was 80.4%. Radiation therapy was effective for improving visual symptoms and headache, but could not normalize amenorrhea and galactorrhoea. There was no difference of survival rate between radiation alone and combination with surgery. Prognostic factors such as age, sex, disease type, visual field, headache and surgical treatment were statistically no significant in survival rates of these patients.

  12. Handbook of graph drawing and visualization

    CERN Document Server

    Tamassia, Roberto

    2013-01-01

    Planarity Testing and Embedding Maurizio PatrignaniCrossings and Planarization Christoph Buchheim, Markus Chimani, Carsten Gutwenger, Michael Jünger, and Petra MutzelSymmetric Graph Drawing Peter Eades and Seok-Hee HongProximity Drawings Giuseppe LiottaTree Drawing Algorithms Adrian RusuPlanar Straight-Line Drawing Algorithms Luca VismaraPlanar Orthogonal and Polyline Drawing Algorithms Christian A. Duncan and Michael T. GoodrichSpine and Radial Drawings Emilio Di Giacomo, Walter Didimo, and Giuseppe LiottaCircular Drawing Algorithms Janet M. Six and Ioannis G. TollisRectangular Drawing Algori

  13. Policy Simulation of the International Coffee Economy.

    Science.gov (United States)

    1981-01-01

    HIGH7 ROUT I NE 1>COFFEE0QUTA2= COFFE §UTA2 EXCEPT tQHD5,C 2>ENAEO05 XSMO 5 EXAFREQH CEXBAEQ5Exl 4> COFFEE @QUOtA2= COFF W OCT7R Q0 >EXNME EXSAI4OT1HEE , 5...AD-AI1N 682 DEPARTMENT OF STATE. WASHINGTON DC OFFICE OF EXTERNAL-ETC F/8 5/3 POLICY SIMULATION OF THE INTERNATIONAL COFFEE ECONOMY.(U) 1981 W C...POLICY SIMULATION OF T=E INTERNATIONAL COFFEE ECONOMY: FINAL REPORT by Walter C. Labys* This final report describes the completed research of the coffee

  14. SOFTWARE TRAINING AIDS DEVELOPMENT AND IMPLEMENTATION IN PROFESSIONAL PREPARATION PRACTICE OF TECHNOLOGICAL EDUCATION TEACHER

    Directory of Open Access Journals (Sweden)

    Anatoliy G. Gritchenko

    2013-03-01

    Full Text Available The article outlines the theoretical and practical aspects of software training aids development and implementation in professional preparation practice of technological education teacher. The myriad opportunities of new information technologies are described; the characteristic features of modern software training tool (STT are revealed; the main algorithmic structure circuits of training programs construction (linear, cyclic, with hyperlinks, to the labels, which enable the development of STT variety and functionality are given; the methodology of STT creating is described based on the analysis of the technology teacher preparation in HEE content, MITE didactic functions and selection criteria of educational software for this area of specialist’s preparation.

  15. Rapid green synthesis of silver and gold nanoparticles using Dendropanax morbifera leaf extract and their anticancer activities

    OpenAIRE

    2016-01-01

    Chao Wang,1 Ramya Mathiyalagan,2 Yeon Ju Kim,1 Veronica Castro-Aceituno,1 Priyanka Singh,1 Sungeun Ahn,1 Dandan Wang,1 Deok Chun Yang1,2 1Department of Oriental Medicine Biotechnology and Ginseng Bank, 2Graduate School of Biotechnology and Ginseng Bank, College of Life Sciences, Kyung Hee University, Yongin, Republic of Korea Abstract: Dendropanax morbifera Léveille is an oriental medicinal plant that is traditionally used in folk medicine and grows in a specific region of South ...

  16. Determination of the pion charge form factor for Q^2 = 0.60-1.60 (GeV/c)^2

    CERN Document Server

    Tadevosyan, V; Huber, G M; Abbott, D; Anklin, H; Armstrong, C; Arrington, J; Assamagan, K A; Avery, S; Baker, O K; Bochna, C; Brash, E J; Breuer, H; Chant, N; Dunne, J; Eden, T; Ent, R; Gaskell, D; Gilman, R; Gustafsson, K; Hinton, W; Jackson, H; Jones, M K; Keppel, C; Kim, P H; Kim, W; Klein, A; Koltenuk, D; Liang, M; Lolos, G J; Lung, A; Mack, D J; McKee, D; Meekins, D; Mitchell, J; Mkrtchyan, H; Müller, B; Niculescu, G N I; Pitz, D; Potterveld, D; Qin, L M; Reinhold, J; Shin, I K; Stepanyan, S; Tang, L G; Van der Meer, R L J; Vansyoc, K; Van Westrum, D; Volmer, J; Vulcan, W; Wood, S; Yan, C; Zhao, W X; Zihlmann, B

    2006-01-01

    The data analysis for the reaction H(e,e' pi^+)n, which was used to determine values for the charged pion form factor Fpi for values of Q2 = 0.6-1.6 (gEv/C)^2, has been repeated with careful inspection of all steps and special attention to systematic uncertainties. Also the method used to extract Fpi from the measured longitudinal cross section was critically reconsidered. Final values for the separated longitudinal and transverse cross sections and the extracted values of Fpi are presented.

  17. Exploitation of the IMS and Other Data for a Comprehensive Advanced Analysis of the North Korean Nuclear Tests

    Science.gov (United States)

    2010-02-01

    98, No. 5, pp. 2498–2506, October 2008, doi: 10.1785/0120080929. Che, Il-Young, Tae Sung Kim, Jeong-Soo Jeon and Hee-Il Lee (2009) Infrasound...Workshop on Seismic Location and Discrimination in Korea, Phillips Lab Report PL-TR-96-2086, 313-322. Herrmann, R., Y. Jeon , H. Yoo, K. Cho, W. Walter, M...mb(Pn), mb(Lg) scales and transportability of the M0:mb discriminant to new tectonic regions,” Bull. Seism. Soc. Am., 87, 1083-1099. Richards, Paul

  18. Disentangling Memories. Complex (Be)longings and Social Categories

    DEFF Research Database (Denmark)

    Pedersen, Chistina Hee; Frølunde, Lisbeth

    2013-01-01

    of the participants and how meaning making connected to social categories express themselves in language. Two different methodological approaches were in play; Memory Work (Haug 1987, 1992, Haug et al 1994, Hee Pedersen 2008, Hyle et. al 2008, Wiederberg 2011) and Collective Biographies (Davies 2000a, 2000b, Davies...... belonging to a specific social or racial group. (Be)longing to a specific gendered and radicalised body constitutes in the analysis of these stories an excellent “location,” from which to analyse how socio/cultural and socio/economic categories like class, nationality and age intersect with one another...

  19. Reference: 105 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available Hee et al. 2004 Sep. Plant Cell 16(9):2406-17. BRASSINOSTEROID-INSENSITIVE 1 (BRI1) is a Leu-rich-repeat (LRR) re...ceptor kinase that functions as a critical component of a transmembrane brassinosteroid (BR) receptor.... It is believed that BRI1 becomes activated through heterodimerization with BAK1, a similar LRR re...ceptor kinase, in response to BR signal. A yeast two-hybrid screen using the kinase domain ...of BRI1 identified an Arabidopsis thaliana Transthyretin-Like protein (TTL) as a potential BRI1 substrate. T

  20. Study of Solar Energetic Particles (SEPs) Using Largely Separated Spacecraft

    Science.gov (United States)

    2016-12-31

    AFRL-AFOSR-JP-TR-2016-0102 Study of solar energetic particles (SEPs) using largely separated spacecraft Jinhye Park KYUNG HEE UNIVERSITY, RESEARCH...energetic particles (SEPs) using largely separated spacecraft 5a.  CONTRACT NUMBER 5b.  GRANT NUMBER FA2386-13-1-4066 5c.  PROGRAM ELEMENT NUMBER 61102F...Release 13. SUPPLEMENTARY NOTES 14. ABSTRACT Solar energetic particles (SEPs) are one of the main activities in terms of space weather forecast. SEPs could

  1. Novel and Efficient Synthesis of the Promising Drug Candidate Discodermolide

    Science.gov (United States)

    2010-02-01

    supported in part by this award: Ph.D. SUNY Stony Brook: Zhou Zhou Ph.D. SUNY Stony Brook: Peng Wang Ph.D. SUNY Stony Brook: Qiu- zhe Xie Ph.D. SUNY...Stolarzewicz Ph.D. SUNY Stony Brook: Pei Wang Continuing in the PhD program at SUNY Stony Brook Junyong Lee Hee Nam Lim Daniel C. Elliot Matthew E...IBS) in Waltham, MA. Intelligent Biosystems is a biotech company that is focused on efficient gene sequencing. Peng Wang is employed by Ren

  2. Supplier Partnership Strategy and Global Competitiveness: A Case of Samsung Electronics

    OpenAIRE

    Jangwoo Lee; Kapsoo Lee; Junseok Heo

    2015-01-01

    Samsung Group has accelerated its management innovation process, following the announcement of ‘New Management’ by the CEO Lee Kun-Hee. Particular attention must be paid to the smart-phone business of Samsung Electronics, which is the core company of the Samsung Group. In 2009, as Apple entered into the Korean market, the domestic smart-phone market faced the so called ‘Apple Shock’ due to its choice of a monopolistic and closed operating system. In response, Samsung Electronics introduced th...

  3. Merkmals- und Prototypensemantik: Eine Einführung

    Directory of Open Access Journals (Sweden)

    Bärenfänger, Olaf

    2002-01-01

    sowie der Umstand, daß die verschiedenen Vertreter einer Kategorie unterschiedlich typisch sein können. Über den Grad der Repräsentativität des Elementes einer Kategorie wird nicht auf der Basis notwendiger, sondern typischer Merkmale entschieden. Das am meisten zentrale Element, der Prototyp, weist die größtmögliche Anzahl typischer Merkmale auf. Welche Elemente überhaupt in eine Kategorie gehören, wird über Familienähnlichkeitsrelationen bestimmt, bei der nicht alle Elemente dieselbe Anzahl notwendiger Merkmale gemeinsam haben müssen, sondern lediglich mindestens ein typisches Merkmal. Im Anschluss an die Darstellung dieser Theoreme werden Konsequenzen für die Argumentation, die Lexikographie und für die linguistische Theorienbildung erwogen. Nach der Erörterung einiger kritikwürdiger Aspekte der Prototypentheorie und der Aufzählung von Forschungsdesideraten gibt ein Schlusskapitel eine kurze Zusammenfassung und benennt die wichtigsten Leistungen dieses zunehmend einflußreichen Forschungsparadigmas.

  4. Positron Emission Tomography: Principles, Technology, and Recent Developments

    Science.gov (United States)

    Ziegler, Sibylle I.

    2005-04-01

    Positron emission tomography (PET) is a nuclear medical imaging technique for quantitative measurement of physiologic parameters in vivo (an overview of principles and applications can be found in [P.E. Valk, et al., eds. Positron Emission Tomography. Basic Science and Clinical Practice. 2003, Springer: Heidelberg]), based on the detection of small amounts of posi-tron-emitter-labelled biologic molecules. Various radiotracers are available for neuro-logical, cardiological, and oncological applications in the clinic and in research proto-cols. This overview describes the basic principles, technology, and recent develop-ments in PET, followed by a section on the development of a tomograph with ava-lanche photodiodes dedicated for small animal imaging as an example of efforts in the domain of high resolution tomographs.

  5. Kas nii nagu ikka? : Eesti Sisearhitektide Liidu 2010. aasta preemiad / Ene Läkk

    Index Scriptorium Estoniae

    Läkk, Ene, 1957-

    2011-01-01

    Konkursist "Eesti interjöörid ja mööblidisain 2010". Söögikoha interjööri preemia: kohvik Supelsaksad Pärnus (Ruth ja Anna Huimerind), ühiskondliku interjööri preemia: ADM Interactive'i bürooruumid Tallinnas (Tomomi Hayashi, Ahti Grünberg, Kerli Valk), ajaloolise interjööri preemia: Kihnu muuseum (Malle Jürgenson, Tea Tammelaan, Krista Lepland, Jaak Huimerind, Indrek Laos), näituse- ja installatsiooni kujunduse preemia: rändnäitus "Eesti kirjanik karikatuuris" (Janno Siimar, Kaarel Vahtramäe, Mart Lankots, Liina Jakobson), tudengipreemia - Aet Tera. 24 nominenti loetletud

  6. Teenetemärkide kandidaadid

    Index Scriptorium Estoniae

    2000-01-01

    Esialgne, kinnitamata nimekiri isikutest, kellele presidendi kantselei ja riigiasutused taotlevad tänavu teenetemärke iseseisvuspäeva puhul. Vt. samas: vastulause, Eesti Päevaleht, 13. jaan. 2001, lk. 11. Valgetähe medal: Enn Tõugu; Ülo Lill; Arda-Maria Kirsel; Valgetähe orden I järk Hillar Aben; Valgetähe orden II järk: Õim, Haldur; Rätsep, Huno; Ross, Juhan; Ergma, Ene; Saarma, Mart; Liidja, Georg; Hižnjakov, Vladimir; Laisk, Agu; Valgetähe ordeni IV klass - Endel Valk-Falk, Valgetähe ordeni V klass - Anne Valmas. Ka bibliograaf Arvo Tering, raamatuloolane Kaljo-Olev Veskimägi, bibliograaf Ilmar Vene, TÜRi rmtk-hoidjad Kaljo Lepik ja Elsa Loorits, raamatuteadlane, TPÜ prof. emer. Mare Lott, TPÜ infoteaduste prof. Evi Rannap

  7. Arhitektuurivõistlused 2001 / Tiina Tammet

    Index Scriptorium Estoniae

    Tammet, Tiina, 1971-

    2001-01-01

    Samas "Europan 6" (I preemia Tallinnas: H. Götz, S. Lippardt, M. Jensch ja Tartus: J. Vuorinen, E. Kangas; II preemia Viinis: S. Vallner, O. Kadarik, K. Koov, R. Valner), Narva keskosa planeeringu (I - I. Raukas, T. Tammis, T. Teedumäe), Pärnu vanalinna põhikooli juurdeehituse (II - O. Kadarik, M. Tüür), Pärnu Kontserdimaja (I - H. Grossschmidt, K. Koov, K. Nõmm), Tallinna 21. keskkooli renoveerimise (I - R. Järg, T. Korb), Eesti lähimineviku okupatsioonide muuseumi (I - S. Vallner, I. Peil), Võru Võidu väljaku pargi kujunduse (I-II - P. Müüripeal; V. Tomiste ja V. Valk), nukuteatri sisekujunduse (I - R. Kotov, A. Kõresaar), Eurovisiooni lavakujunduse (I - H. Ermel, A. Nurmela, Ü. Mark) arhitektuurivõistluse tulemused.

  8. Time, Sense and Meaning in Three Votic Songs (with Reference to Estonian and Setu Additions

    Directory of Open Access Journals (Sweden)

    Madis Arukask

    2004-12-01

    Full Text Available The article investigates Votic, Estonian and Setu Kalevala-metric folk songs, which describe a dialogue between a living person and his or her deceased relative. The analysis centres on religious truth in poetic texts, relying on corresponding approaches by Ülo Valk and Aado Lintrop. As the observed texts are no longer mytho-epic stories or laments, the question about the meaning in lyro-epic discourse is discussed and particular attention is paid to the changes in concepts of time, the plot and characters of the songs. The author introduces the key concept ‘epiphany’ as a tool constructing meaning and merging the actual situation, the song text and personal emotions into a creative whole for the singer and/ or the audience.

  9. Enhanced validamycin production and gene expression at elevated temperature in Streptomyces hygroscopicus subsp. Jingangensis 5008

    Institute of Scientific and Technical Information of China (English)

    LI Lei; BAI LinQuan; ZHOU XiuFen; DENG ZiXin

    2009-01-01

    Cultivation shift from 30℃ to 37℃ significantly enhanced validamycin (VAL) production. Analyzed by reverse-transcripUon PCR, the transcription of three val genes, valA, valK and valG, representing the three operons of the cluster was simultaneously increased at elevated temperature. Furthermore, the transcription of valP and valQ, a pair of two-component regulators in validamycin biosynthetic gene cluster, was also increased at 37℃. Inactivation of valPand valQ reduced validamycin production at 37℃ to the yield level of wild type strain at 30℃, and the val genes showed reduced expression in the mutant LL-8 at 37℃. These results revealed that the two-component regulator valP and valQ contribute to the elevated validamycin production.

  10. Arhitektuurivõistlused 2001 / Tiina Tammet

    Index Scriptorium Estoniae

    Tammet, Tiina, 1971-

    2001-01-01

    Samas "Europan 6" (I preemia Tallinnas: H. Götz, S. Lippardt, M. Jensch ja Tartus: J. Vuorinen, E. Kangas; II preemia Viinis: S. Vallner, O. Kadarik, K. Koov, R. Valner), Narva keskosa planeeringu (I - I. Raukas, T. Tammis, T. Teedumäe), Pärnu vanalinna põhikooli juurdeehituse (II - O. Kadarik, M. Tüür), Pärnu Kontserdimaja (I - H. Grossschmidt, K. Koov, K. Nõmm), Tallinna 21. keskkooli renoveerimise (I - R. Järg, T. Korb), Eesti lähimineviku okupatsioonide muuseumi (I - S. Vallner, I. Peil), Võru Võidu väljaku pargi kujunduse (I-II - P. Müüripeal; V. Tomiste ja V. Valk), nukuteatri sisekujunduse (I - R. Kotov, A. Kõresaar), Eurovisiooni lavakujunduse (I - H. Ermel, A. Nurmela, Ü. Mark) arhitektuurivõistluse tulemused.

  11. New energy crop giant cane (Arundo donax L.) can substitute traditional energy crops increasing biogas yield and reducing costs.

    Science.gov (United States)

    Luca, Corno; Pilu, Roberto; Tambone, Fulvia; Scaglia, Barbara; Adani, Fabrizio

    2015-09-01

    Giant cane is a promising non-food crop for biogas production. Giant cane and corn silages coming from full-scale fields were tested, in mixtures with pig slurry, for biomethane production by a continuous stirred tank lab-scale-reactor (CSTR) approach. Results indicated that giant cane produced less biomethane than corn, i.e. 174±10 N m(3) CH4 Mg(-1) TS(-1) and 245±26 N m(3) CH4 Mg(-1) TS(-1), respectively. On the other hand, because of its high field biomass production, the biogas obtainable per Ha was higher for giant cane than for corn, i.e. 12,292 N m(3) CH4 Ha(-1) and 4549 N m(3) CH4 Ha(-1), respectively. Low energetic and agronomic inputs for giant cane cultivation led to a considerable reduction in the costs of producing both electricity and biomethane, i.e. 0.50 € N m(-3) CH4(-1) and 0.81 € N m(-3) CH4(-1), and 0.10 € kW hEE(-1) and 0.19 € kW hEE(-1) for biomethane and electricity production, and for giant cane and corn mixtures respectively.

  12. Hybrid Enhanced Epidermal SpaceSuit Design Approaches

    Science.gov (United States)

    Jessup, Joseph M.

    A Space suit that does not rely on gas pressurization is a multi-faceted problem that requires major stability controls to be incorporated during design and construction. The concept of Hybrid Epidermal Enhancement space suit integrates evolved human anthropomorphic and physiological adaptations into its functionality, using commercially available bio-medical technologies to address shortcomings of conventional gas pressure suits, and the impracticalities of MCP suits. The prototype HEE Space Suit explored integumentary homeostasis, thermal control and mobility using advanced bio-medical materials technology and construction concepts. The goal was a space suit that functions as an enhanced, multi-functional bio-mimic of the human epidermal layer that works in attunement with the wearer rather than as a separate system. In addressing human physiological requirements for design and construction of the HEE suit, testing regimes were devised and integrated into the prototype which was then subject to a series of detailed tests using both anatomical reproduction methods and human subject.

  13. Preliminary phytochemical, pharmacological and antibacterial studies of the alkaloidal extracts of the leaves of Synclisia scabrida Miers.

    Science.gov (United States)

    Sokomba, E; Wambebe, C; Chowdhury, B K; Iriah, J; Ogbeide, O N; Orkor, D

    1986-11-01

    Preliminary phytochemical investigation of the leaves of Synclisia scabrida indicated the presence of two alkaloids in the water extracts and five alkaloids in the ethanol extracts. The alkaloidal fraction obtained from the cold ethanol extract furnished on column-chromatography, a homogeneous amorphous solid which has been designated as alkaloid C. Alkaloid C showed positive test for alkaloids. The UV and IR spectra and colour reactions of alkaloid C indicated that the compound may be a phenolic bisbenzylisoquinoline alkaloid. All the extracts delayed the onset and shortened the duration of apomorphine-induced stereotyped behaviour in chicks. In addition, 40 mg kg-1 i.p. of the ethanolic extract induced catalepsy in rats. The cold water extract (CWE) synchronized the EEG of the hyperstriatum, optic tectum and the reticular formation while the EMG activity was slightly enhanced. The hot ethanol alkaloidal extract (HEE) inhibited the growth of Pseudomonas aeruginosa and Staphylococcus aureus. The minimum inhibitory concentration of HEE on Pseudomonas aeruginosa strains I and II were 5 and 2.5 micrograms/ml while for Staphylococcus aureus strains I and II were 5 and 10 micrograms/ml, respectively. Up to 1 g kg-1 i.p. of the extract failed to induce any lethal effect in chicks and rats. These effects of the leaf extracts of Synclisia scabrida Miers support some of the local uses of the plant by traditional medical practitioners.

  14. Genomics education for medical professionals - the current UK landscape.

    Science.gov (United States)

    Slade, Ingrid; Subramanian, Deepak N; Burton, Hilary

    2016-08-01

    Genomics education in the UK is at an early stage of development, and its pace of evolution has lagged behind that of the genomics research upon which it is based. As a result, knowledge of genomics and its applications remains limited among non-specialist clinicians. In this review article, we describe the complex landscape for genomics education within the UK, and highlight the large number and variety of organisations that can influence, direct and provide genomics training to medical professionals. Postgraduate genomics education is being shaped by the work of the Health Education England (HEE) Genomics Education Programme, working in conjunction with the Joint Committee on Genomics in Medicine. The success of their work will be greatly enhanced by the full cooperation and engagement of the many groups, societies and organisations involved with medical education and training (such as the royal colleges). Without this cooperation, there is a risk of poor coordination and unnecessary duplication of work. Leadership from an organisation such as the HEE Genomics Education Programme will have a key role in guiding the formulation and delivery of genomics education policy by various stakeholders among the different disciplines in medicine.

  15. Tiam1 gene expression and its significance in colorectal carcinoma

    Institute of Scientific and Technical Information of China (English)

    Li Liu; De-Hua Wu; Yan-Qing Ding

    2005-01-01

    AIM: To explore the expression of Tiam1 gene in colorectal carcinoma and its correlation with tumor metastasis.METHODS: Expressions of Tiam1 gene in 8 colorectal carcinoma cell lines were detected by reverse transcriptasepolymerase chain reaction. In vitro invasiveness was determined by means of Matrigel invasion assay. The correlation of Tiam1 expression with the invasive ability was also analyzed.RESULTS: Tiam1 gene was highly expressed in LoVo and SW620, which were established from metastatic colorectal carcinomas in comparison with LS174T, SW480, HCT116,LST, HRT-18 and Hee8693, which were established from primary colorectal carcinomas. In vitro cell invasivion demonstrated that LoVo and SW620 had a higher invasive ability than LS174T, SW480, HCT116, LST, HRT-18 and Hee8693. The expression of Tiam1 gene was highly related to the metastatic potential of colorectal carcinoma cells.CONCLUSION: Tiam1 gene may play an important role in invasion and metastasis of colorectal carcinoma and is a metastasis-related gene.

  16. Induced Pluripotent Stem Cell Differentiation and Three-Dimensional Tissue Formation Attenuate Clonal Epigenetic Differences in Trichohyalin.

    Science.gov (United States)

    Petrova, Anastasia; Capalbo, Antonio; Jacquet, Laureen; Hazelwood-Smith, Simon; Dafou, Dimitra; Hobbs, Carl; Arno, Matthew; Farcomeni, Alessio; Devito, Liani; Badraiq, Heba; Simpson, Michael; McGrath, John A; Di, Wei-Li; Cheng, Jeffrey B; Mauro, Theodora M; Ilic, Dusko

    2016-09-15

    The epigenetic background of pluripotent stem cells can influence transcriptional and functional behavior. Most of these data have been obtained in standard monolayer cell culture systems. In this study, we used exome sequencing, array comparative genomic hybridization (CGH), miRNA array, DNA methylation array, three-dimensional (3D) tissue engineering, and immunostaining to conduct a comparative analysis of two induced pluripotent stem cell (iPSC) lines used in engineering of 3D human epidermal equivalent (HEE), which more closely approximates epidermis. Exome sequencing and array CGH suggested that their genome was stable following 3 months of feeder-free culture. While the miRNAome was also not affected, ≈7% of CpG sites were differently methylated between the two lines. Analysis of the epidermal differentiation complex, a region on chromosome 1 that contains multiple genes involved in skin barrier maturation (including trichohyalin, TCHH), found that in one of the iPSC clones (iKCL004), TCHH retained a DNA methylation signature characteristic of the original somatic cells, whereas in other iPSC line (iKCL011), the TCHH methylation signature matched that of the human embryonic stem cell line KCL034. The difference between the two iPSC clones in TCHH methylation did not have an obvious effect on its expression in 3D HEE, suggesting that differentiation and tissue formation may mitigate variations in the iPSC methylome.

  17. Hemangioendotelioma Epitelioide Pulmonar: reporte de un caso

    Directory of Open Access Journals (Sweden)

    Victoria Monterroso-Azofeifa

    2001-06-01

    Full Text Available En 1983 se reportaron 20 enfermos con un tumor pulmonar raro que fue entonces llamado IVBAT, por sus siglas en inglés (tumor intravascular bronquio-alveolar. Los pacientes se presentaron con numerosos nódulos pulmonares, de crecimiento lento, cuyos hallazgos histológicos variaban desde una apariencia benigna granulomatosa hasta una claramente maligna sarcomatosa. Eventualmente se demostró que el tumor era de origen vascular y se le llamó hemangioendotelioma epiteliode (HEE. Poco después se describió en otras regiones anatómicas. Reportamos aquí el primer caso costarricense de esta estirpe histológica y de presentación pulmonar. Un hombre de 42 años de edad, nos fue referido en fase final con metástasis generalizadas, aunque en buenas condiciones generales. Se le practicó una biopsia pulmonar para definir la histología, pero falleció poco tiempo después sin responder a la terapia instituida. Dieciséis años antes se le habían descubierto nódulos pulmonares pequeños bilaterales y mediante una biopsia abierta se le hizo el diagnostico de HEE. Como el curso de su enfermedad fue considerado estable durante ese tiempo había sido seguido clínicamente. Se comparó el material de la biopsia inicial con el de la reciente, encontrándose mucho mayor celularidad y atipia en la última. Se efectuaron análisis inmunohistoquímicos con un panel de anticuerpos, que permitió establecer la naturaleza vascular del tumor. El HEE es un tumor muy raro, de crecimiento lento y de bajo potencial metastásico, a pesar de ser de origen vascular. Llama la atención el fenómeno de dependencia hormonal de este tumor, que se plantea en la literatura, y que sugiere otras avenidas terapéuticas.

  18. Hydrogen Embrittlement

    Science.gov (United States)

    Woods, Stephen; Lee, Jonathan A.

    2016-01-01

    Hydrogen embrittlement (HE) is a process resulting in a decrease in the fracture toughness or ductility of a metal due to the presence of atomic hydrogen. In addition to pure hydrogen gas as a direct source for the absorption of atomic hydrogen, the damaging effect can manifest itself from other hydrogen-containing gas species such as hydrogen sulfide (H2S), hydrogen chloride (HCl), and hydrogen bromide (HBr) environments. It has been known that H2S environment may result in a much more severe condition of embrittlement than pure hydrogen gas (H2) for certain types of alloys at similar conditions of stress and gas pressure. The reduction of fracture loads can occur at levels well below the yield strength of the material. Hydrogen embrittlement is usually manifest in terms of singular sharp cracks, in contrast to the extensive branching observed for stress corrosion cracking. The initial crack openings and the local deformation associated with crack propagation may be so small that they are difficult to detect except in special nondestructive examinations. Cracks due to HE can grow rapidly with little macroscopic evidence of mechanical deformation in materials that are normally quite ductile. This Technical Memorandum presents a comprehensive review of experimental data for the effects of gaseous Hydrogen Environment Embrittlement (HEE) for several types of metallic materials. Common material screening methods are used to rate the hydrogen degradation of mechanical properties that occur while the material is under an applied stress and exposed to gaseous hydrogen as compared to air or helium, under slow strain rates (SSR) testing. Due to the simplicity and accelerated nature of these tests, the results expressed in terms of HEE index are not intended to necessarily represent true hydrogen service environment for long-term exposure, but rather to provide a practical approach for material screening, which is a useful concept to qualitatively evaluate the severity of

  19. Reference: 660 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available he cauliflower mosaic virus 35S enhancer normally responded to vernalization and gibberellic acid treatments...utant, FT was significantly repressed, but other flowering genes were unaffected. Notably, miR172 abundance ...is regulated by photoperiod via GI-mediated miRNA processing. Accordingly, miR172-overproducing plants exhib...it early flowering under both long days and short days, even in the absence of functional CO, indicating tha...CONSTANS in Arabidopsis. 9 2736-48 17890372 2007 Sep The Plant cell Chua Nam-Hai|Jung Jae-Hoon|Park Chung-Mo|Reyes Jose Luis|Seo Pil Joon|Seo Yeon-Hee|Yun Ju

  20. International Cooperation of the Cosmic Infrared Background Experiment

    Science.gov (United States)

    Lee, D.-H.; Nam, U.-W.; Lee, S.; Jin, H.; Yuk, I.-S.; Kim, K.-H.; Pak, S.

    2006-12-01

    A Korean team (Korea Astronomy and Space Science Institute, Korea Basic Science Institute, and Kyung Hee University) takes part in an international cooperation project called CIBER (Cosmic Infrared Background ExpeRiment), which has begun with Jet Propulsion Laboratory (JPL) in USA and Institute of Space and Astronautical Science (ISAS) in Japan. CIBER is a rocket-borne instrument, of which the scientific goal is to measure the cosmic near-infrared extra-galactic background to search for signatures of primordial galaxy formation. CIBER consists of a wide-field two-color camera, a low-resolution absolute spectrometer, and a high-resolution narrow-band imaging spectrometer. The Korean team is in charge of the ground support electronics and manufacturing of optical parts of the narrow-band spectrometer, which will provide excellent opportunities for science and technology to Korean infrared groups.

  1. Dento-maxillofacial abnormalities caused by radiotherapy and chemotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Park, Cheol Woo; Hwang, Eui Hwang; Lee, Sang Rae [Dept. of Oral and Maxillofacial Radiology, College of Dentistry, Kyunghee University, Seoul (Korea, Republic of)

    2000-12-15

    A case of dento-maxillofacial abnormality involving a 10-year-old male patient with a history of esthesioneuroblastoma is presented. This patient had been treated with 54 Gy {sup 60}Co-gamma-radiation to the nasal cavity for 6 weeks and 6 cycles of combination chemotherapy of Cyclophosphamide, Cisplatin, Adriamycin, VM-26 (Teniposide), and DTIC (Dacarbazine) when he was 16 months of age. Five years after cessation of cancer therapy, he was disease free and transferred for extensive dental care to Kyung Hee University Dental Hospital. A clinical and radiologic follow-up over last 4 years showed root stunting, premature closure of the root apices, microdontia, developmental arrest, small crowns, and partial anodontia. Maxillofacial morphology evaluated by cephalometric analysis showed deficiency of maxillary development.

  2. Reference Cap of Poly Vinyl Alcohol for Quantitative Elastography of the Human Uterine Cervix

    DEFF Research Database (Denmark)

    Leonhard, Anne Katrine; Sandager, Puk; Rasmussen, Christina Kjærgaard

    CONTROL ID: 2522419 ABSTRACT FINAL ID: EP22.04 TITLE: Reference Cap of Poly Vinyl Alcohol for Quantitative Elastography of the Human Uterine Cervix AUTHORS (FIRST NAME, LAST NAME): Anne Katrine Leonhard1, Puk Sandager1, Christina K. Rasmussen1, Hee Lene1, Niels Uldbjerg1 INSTITUTIONS (ALL): 1....... Department of Obstetrics and Gynecology, Aarhus University Hospital, Aarhus N, Denmark. ABSTRACT BODY: Objectives: To develop a reference cap for the ultrasound probe that allows for quantitative elastography of the cervical uterine tissue with preservation of a good ultrasonic image. Further to perform...... inter-intra observer evaluations. Methods: Two types of reference caps were developed. Cap 1 made of Poly Vinyl Alcohol [PVA] with the Young’s modulus [E] of 0.09 N/mm2. Cap 2 made of silicone and oil with the Young’s modulus of 0.4 N/mm2. Elastography was conducted with the caps applied to a 2D...

  3. Retraction Statement: Unrecognized High Brachial Artery Bifurcation is Associated with Higher Rate of Dialysis Access by Dr. Lee Kirksey.

    Science.gov (United States)

    2017-03-01

    The above article from Seminars in Dialysis, published online on 4 September 2011 in Wiley Online Library (http://wileyonlinelibrary.com) has been retracted by agreement among the journal's Editor-in-Chief, Richard A. Sherman MD, the journal's North American editor of ASDIN content at the time, Arif Asif MD, and Wiley Periodicals, Inc. The decision to retract was agreed upon following notification by Dr. HeeJun Yang, the author of an article published in 2008, "Variations of the Superficial Brachial Artery in Korean Cadavers." Figure 1 (A & B) and Figure 2 (A-C) in the Kirksey article (1), which originally appeared in the 2008 article by Dr. Yang, were used without authorization or permission from Dr. Yang or the article's publisher. Reference Kirksey L: Unrecognized high brachial artery bifurcation is associated with higher rate of dialysis access. Semin Dial 24(6):698-702, 2011. doi: 10.1111/j.1525-139X.2011.00923.x.

  4. Organization of Military Aeronautics, 1907-1935. Congressional and War Department Action

    Science.gov (United States)

    1944-12-01

    ico:nore th~ issue nQ longer. Cn 1$ Jv.u- U:l:r’.l 1’)26 lLepre5":11t,~tive John’ : orin ~Fe..) sa.bmilited H. 1.1.. 7916, culled th~ :.ir bill, \\·hl.ch...see Sec. of ar to ~:~prc::’GJt;..t.lvc John :: orin , 10 reb. 1926, in ibid., 496-99. 59. Ccn;;. Hee., 69 C’.),l,_., 1 ...O::’G., ’)731) (10 b.:b. 1926...George S. Simonds, Jama8 H. Doolittle, Edgar S. Gorrell, Brig. Gen• .1. 1’:. Gulick, ll:aj. Gen. B. D. Foulois, Clarence D. Chamberlain, and Maj. Albert

  5. Correction of physical education program for technical higher educational establishment girl-students on the base of their health indicators

    Directory of Open Access Journals (Sweden)

    Kolumbet A.N.

    2016-12-01

    Full Text Available Purpose: to illustrate opportunities of physical education in health strengthening of technical HEE girl-students through correction of their biological age components. Material: 127 girl-students participated in the research. Results : the authors’ program of biological age correction permitted to increase breathing pauses, hand strength, time of static balance and reduce blood pressure. Knowledge of biological age and mechanisms of too early ageing facilitates practicing healthy life style and formation of body-motor conditions. We offered trainings of biological age correction’ methodic, oriented on prophylaxis of organism’s ageing, reduction of biological age and prolongation girl-students’ active life. Conclusions: specially determined biological age of an individual can be used as integral characteristic of his/her health condition.

  6. Clinical applications of therapeutic phlebotomy

    Directory of Open Access Journals (Sweden)

    Kim KH

    2016-07-01

    Full Text Available Kyung Hee Kim,1 Ki Young Oh,2 1Department of Laboratory Medicine, Gachon University Gil Medical Center, Incheon, 2Department of Physical Medicine and Rehabilitation, Soonchunhyang University, Cheonan Hospital, Cheonan, South Korea Abstract: Phlebotomy is the removal of blood from the body, and therapeutic phlebotomy is the preferred treatment for blood disorders in which the removal of red blood cells or serum iron is the most efficient method for managing the symptoms and complications. Therapeutic phlebotomy is currently indicated for the treatment of hemochromatosis, polycythemia vera, porphyria cutanea tarda, sickle cell disease, and nonalcoholic fatty liver disease with hyperferritinemia. This review discusses therapeutic phlebotomy and the related disorders and also offers guidelines for establishing a therapeutic phlebotomy program. Keywords: therapeutic phlebotomy, hemochromatosis, polycythemia vera, porphyria cutanea tarda, sickle cell disease, nonalcoholic fatty liver disease

  7. Journal Of The Korean Hydrogen Energy Society 3

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-11-15

    This book is the Journal of the Korean hydrogen energy society, which includes study on the improvement of the electrochemical characteristics of surface-modified V-Ti-Cr alloy by Ball-milling by Kim, Jin Ho; Lee, Sang Min; Lee, Ho; Lee, Paul S. and Lee, Jai Young, hydrogen generation from water using cds-zns photocatalysts by Heo, Gwi Suk, characteristics of Y-Hx Film by Cho, Young Sin; Kim, Sun Hee, and effect of Cu powder as a compacting material on the discharge characteristics of the negative electrode of Ni-MH battery by Jung, J. H.; Han, Y. S.; Yu, J. S.; Jang, K. J.; Lee, J. Y.

  8. Dealing with Multistate Reporting Requirements

    Science.gov (United States)

    1992-07-01

    Source Code: F. Form Code: O. Origin: ~Systes: M141 H. TRI Constituent: I. CAS numbers: .1 2. ". A.. aL geerate d S.uantity generated C.DENSI wa hee...DOXZs - NOT REM. NOT APPLICABL320 P Z A HAULER PA 0.D. NO. RECEZVING SITE AMOUNT COD AI NO. EPA 1.0. NO. IN POUNDSI 1iCR191E 01 324 DESCRIPTION: T18 PD...instuctionas on the back of this page before completing tis form. Siloe A. VPA 19h.SIll .ýuW1I9vSww L %&me el off-*" .ww*UJw or61r IC ,O F D V I z

  9. Interaction between EphrinB1 and CNK1 Found to Play Role in Tumor Progression | Poster

    Science.gov (United States)

    By Nancy Parrish, Staff Writer The family of proteins known as ephrins plays a critical role in a variety of biological processes. In a recent article in the Journal of Biological Chemistry, Hee Jun Cho, Ph.D., and colleagues report on the interaction between proteins CNK1 and ephrinB1 that promotes cell movement. Their findings may have an important implication in developing new therapeutics for reducing metastases in certain cancers. “Eph and ephrin signaling has become an area of intense interest due to the influence these molecules exert on the control of cell adhesion and cell movement,” Cho said. “This signaling affects the formation of tissues during development and has been shown to play an instructive role in angiogenesis, as well as tumor cell invasion.”

  10. Research in theoretical and elementary particle physics

    Energy Technology Data Exchange (ETDEWEB)

    Mitselmakher, G. [Univ. of Florida, Gainesville, FL (United States)

    1996-12-01

    In 1995 the University of Florida started a major expansion of the High Energy Experimental Physics group (HEE) with the goal of adding four new faculty level positions to the group in two years. This proposal covers the second year of operation of the new group and gives a projection of the planned research program for the next five years, when the group expects their activities to be broader and well defined. The expansion of the HEE group started in the Fall of 1995 when Guenakh Mitselmakher was hired from Fermilab as a Full Professor. A search was then performed for two junior faculty positions. The first being a Research Scientist/Scholar position which is supported for 9 months by the University on a faculty line at the same level as Assistant Professor but without the teaching duties. The second position is that of an Assistant Professor. The search has been successfully completed and Jacobo Konigsberg from Harvard University has accepted the position of Research Scientist and Andrey Korytov from MIT has accepted the position of Assistant Professor. They will join the group in August 1996. The physics program for the new group is focused on hadron collider physics. G. Mitselmakher has been leading the CMS endcap muon project since 1994. A Korytov is the coordinator of the endcap muon chamber effort for CMS and a member of the CDF collaboration and J. Konigsberg is a member of CDF where he has participated in various physics analyses and has been coordinator of the gas calorimetry group. The group at the U. of Florida has recently been accepted as an official collaborating institution on CDF. They have been assigned the responsibility of determining the collider beam luminosity at CDF and they will also be an active participant in the design and operation of the muon detectors for the intermediate rapidity region. In addition they expect to continue their strong participation in the present and future physics analysis of the CDF data.

  11. Transformation of Chlorpyrifos and Chlorpyrifos-Methyl in Prairie Pothole Porewaters

    Science.gov (United States)

    Anderson, R. M.; Chin, Y. P.

    2014-12-01

    The prairie pothole region (PPR) extends over approximately 700,000 km2 in the Great Plains region in United States and Canada and is a critical breeding ground for migratory waterfowl, as well as an important ecosystem for diverse invertebrates and aquatic plants (van der Valk, 2003). Consisting of up to 12 million permanent and temporary depressional wetlands, the PPR is negatively impacted by non-point source pesticide pollution due to extensive agricultural development in the region. Recent studies have shown that high (mM) levels of sulfate in the pothole lakes are capable of abiotically reducing dinitroaniline and chloroacetanilide pesticides (Zeng, 2011; Zeng, 2012). In this study the transformation of the organophosphorus pesticide chlorpyrifos (CP) and its analog chlorpyrifos-methyl (CPM) was studied using pore waters sampled from two pothole lakes. CP and CPM have been found to react in the laboratory with sulfur species via a SN2 mechanism, with degradation by sulfur compounds occurring faster than hydrolysis at high pH (Wu, 2006). To date the reaction of CP and CPM in natural environments with sulfur species has not been studied. Chlorpyrifos-methyl underwent rapid degradation in the presence of reduced sulfur species in pore water, while chlorpyrifos degradation occurred at significantly slower rates. Both CP and CPM degradation occurred at comparable rates to what has been previously observed in the laboratory (Wu, 2006). References van der Valk, Arnold G., and Roger L. Pederson. "The SWANCC decision and its implications for prairie potholes." Wetlands 23.3 (2003): 590-596. Wu, Tong, Qiu Gan, and Urs Jans. "Nucleophilic Substitution of Phosphorothionate Ester Pesticides with Bisulfide (HS-) and Polysulfides (Sn2-)." Environmental science & technology 40.17 (2006): 5428-5434. Zeng, Teng, et al. "Pesticide processing potential in prairie pothole porewaters."Environmental science & technology 45.16 (2011): 6814-6822. Zeng, Teng, Yu-Ping Chin, and William

  12. Instaurare omnia in Christo des Papstes Pius’ X. (1903-1914 und die liturgische Erneuerung

    Directory of Open Access Journals (Sweden)

    Jan Józef Janicki

    2004-12-01

    Full Text Available Papst Pius X. (1903-1914 hat sein Pontifikat, das unter dem Motto Instaurare omnia in Christo („Alles in Christo erneuern” stand, mit der Erneuerung der Liturgie angefangen. Bei seinem eifrigen Streben, Kirche und Menscheit durch Wiederbelebung der Frömmigkeit zu erneuern, war Pius X. auch um die Reinheit und Erhabenheit der gottesdienstlichen Formen besorgt. Seine Reformen auf diesem Gebiet bezogen sich zunächst auf die kirchliche Musik, die damals besonders in Italien verweltlicht und entartet war. Das Motu proprio Tra le sollecitudini vom 22. November 1903 (Fest der heiligen Cäcilia (das sich direkt auf die Kirchenmusik bezog, sollte nach Pius’X. eigenen Worten ein Grundbuch der Kirchenmusik sein. Unter seinen Hirtensorgen, so führt der Papst aus, rage diejenige für die Würde des Gotteshauses hervor, in dem sich die Gläubigen zur Feier der Geheimnisse und Verrichtung ihrer Gebete versammeln und also nichts geschehen dürfe, was ihre Frömmigkeit stören und die Heiligkeit des Ortes beleidigen könnte, wie dies die kirchenmusikalischen Abwege und Missbrauche unter dem Einfluss der profanen Kunst zu tun drohten. Die Kirchenmusik müsse als integraler Bestandteil der Liturgie die Ehre Gottes und die Andacht der Zuhörer fördern und daher heilig, universell und künstlerisch sein. Von besonderer Bedeutung sind im Werke des grossen Seelsorgepapstes die Kommunionerlasse. Im Dekret der Konzilskongregation vom 20. Dezember 1905 erklärte Pius X. als Wunsch Christi und der Kirche, dass alle Gläubigen öfters, ja möglichst jeden Tag in würdiger Weise zum heiligen Mahle gehen möchten, um durch die eucharistische Vereinigung mit Gott als Heilmittel gegen ihre Gebrechen, nicht etwa als Lohn für ihre Tugenden, die Kraft zur Stärkung der Liebe zu gewinnen. Am 8. August 1910 erklärte die Sakramentskongregation mit ausführlicher dogmatischer Begründung und päpstlicher Bestätigung, es genüge zur ersten heiligen Kommunion, dass ein

  13. Suvine Tallinn on täis head tarbekunsti, ka harrastajad on aktiivsed / Andri Ksenofontov

    Index Scriptorium Estoniae

    Ksenofontov, Andri, 1962-

    2005-01-01

    Andres ja Katja Koorti korraldatud kobarnäitus "18 tuba" Sakala t. 9 majas, Adolfas Shaulyse ja Mari Relo-Shaulyse näitus "Viva la vida!" A-galeriis, Piret Räni näitus "Hello friend - are you impotent?" EKA galeriis, Tiina Piisangu tööd köitekunstinäitusel "Scripta manent III. Maailma parim asi" Eesti Tarbekunsti- ja Disainimuuseumis, Kristiina Kalistru ja Silvia Kelle tööd Kullo galeriis, Anne Türni tööd ja väljapanek Lühikese jala galeriis, Eesti Keraamikute Liidu puupõletustehnikas teostatud tööde näitus arhitektuurimuuseumis, Thomas Häntzscheli fotode näitus ArtDepoos, Angelika Kauffmanni näitus Kadrioru Kunstimuuseumis, Adam Greeni ja Simona Dell'Agli näitus "Tekkimine" Tallinna Linnagaleriis, Merike Estna maalinäitus "The Sexiest Girl, Pussycat, the Happiest Girl and Two Loverabbits" Haus galeriis, Monica del Norte maalinäitus "Lugupilt" G-galeriis, Päivi Randveri näitus "Reisid kosmosesse" Draakoni galeriis, Kelli Valk Kagovere näitus "Kõik muutub" Ühispanga galeriis, Toomas Sarapuu näitus "Deebetkaart" Tallinna Kunstihoone galeriis jm.

  14. Suvine Tallinn on täis head tarbekunsti, ka harrastajad on aktiivsed / Andri Ksenofontov

    Index Scriptorium Estoniae

    Ksenofontov, Andri, 1962-

    2005-01-01

    Andres ja Katja Koorti korraldatud kobarnäitus "18 tuba" Sakala t. 9 majas, Adolfas Shaulyse ja Mari Relo-Shaulyse näitus "Viva la vida!" A-galeriis, Piret Räni näitus "Hello friend - are you impotent?" EKA galeriis, Tiina Piisangu tööd köitekunstinäitusel "Scripta manent III. Maailma parim asi" Eesti Tarbekunsti- ja Disainimuuseumis, Kristiina Kalistru ja Silvia Kelle tööd Kullo galeriis, Anne Türni tööd ja väljapanek Lühikese jala galeriis, Eesti Keraamikute Liidu puupõletustehnikas teostatud tööde näitus arhitektuurimuuseumis, Thomas Häntzscheli fotode näitus ArtDepoos, Angelika Kauffmanni näitus Kadrioru Kunstimuuseumis, Adam Greeni ja Simona Dell'Agli näitus "Tekkimine" Tallinna Linnagaleriis, Merike Estna maalinäitus "The Sexiest Girl, Pussycat, the Happiest Girl and Two Loverabbits" Haus galeriis, Monica del Norte maalinäitus "Lugupilt" G-galeriis, Päivi Randveri näitus "Reisid kosmosesse" Draakoni galeriis, Kelli Valk Kagovere näitus "Kõik muutub" Ühispanga galeriis, Toomas Sarapuu näitus "Deebetkaart" Tallinna Kunstihoone galeriis jm.

  15. Photographing travel of classical windturbines in Europe; Oshu Koen fusha satsuei ryoko

    Energy Technology Data Exchange (ETDEWEB)

    Suzuki, H.

    1997-03-01

    Travel in Europe for taking photographs of classical windturbines is reported. The Netherlands which is a representative windturbine country, Spain which is a theme country of this travel, Greece which is a root country of the windmills, and the UK with the Windturbine Museum were visited. In the Netherlands, photographs of Kinder d`eiche Windturbine, Leiden de Valk Windturbine Museum, and a windturbine in the south end of Amstle Park were taken. Photographs of don Quijote Windturbine at Campo de Criptana in Spain, and Crete Windturbine and sail-type windturbine in the Rhodes Island, Greece were taken. In the UK, the Windturbine Museum was visited at Wimbledon. After coming back to Japan, films were exposed. The walls of windturbines were dark due to insufficient exposure against the light sky. In spite of consideration of the exposure, 70% of the photographs of windturbine walls were still dark. Only 10% of them can be available. This may be a limit of amateur photographer. Professional photographer may be complete. 12 figs.

  16. Ierobežojuma nēsāt seju aizsedzošu apģērbu tiesiskais regulējums

    OpenAIRE

    Ozoliņa, Zane

    2016-01-01

    Bakalaura darba tēma ir “Ierobežojuma nēsāt seju aizsedzošu apģērbu tiesiskais regulējums”. Šāds regulējums var aizskart personas tiesības uz reliģiskās pārliecības brīvību, jo galvassegu valkāšana ir viens no reliģiskās pārliecības izpausmes veidiem, īpaši islāma ticīgām sievietēm. Tā kā ierobežojums var tikt noteikts arī Latvijas normatīvajos aktos, ir nepieciešams izvērtēt tā ieviešanas nepieciešamību. Darba mērķis ir analizēt iespējamos iemeslus ierobežojuma nepieciešamībai. Darbā autore ...

  17. Hemangioendotelioma Epitelioide Pulmonar: reporte de un caso

    Directory of Open Access Journals (Sweden)

    Victoria Monterroso-Azofeifa

    2001-06-01

    Full Text Available En 1983 se reportaron 20 enfermos con un tumor pulmonar raro que fue entonces llamado IVBAT, por sus siglas en inglés (tumor intravascular bronquio-alveolar. Los pacientes se presentaron con numerosos nódulos pulmonares, de crecimiento lento, cuyos hallazgos histológicos variaban desde una apariencia benigna granulomatosa hasta una claramente maligna sarcomatosa. Eventualmente se demostró que el tumor era de origen vascular y se le llamó hemangioendotelioma epiteliode (HEE. Poco después se describió en otras regiones anatómicas. Reportamos aquí el primer caso costarricense de esta estirpe histológica y de presentación pulmonar. Un hombre de 42 años de edad, nos fue referido en fase final con metástasis generalizadas, aunque en buenas condiciones generales. Se le practicó una biopsia pulmonar para definir la histología, pero falleció poco tiempo después sin responder a la terapia instituida. Dieciséis años antes se le habían descubierto nódulos pulmonares pequeños bilaterales y mediante una biopsia abierta se le hizo el diagnostico de HEE. Como el curso de su enfermedad fue considerado estable durante ese tiempo había sido seguido clínicamente. Se comparó el material de la biopsia inicial con el de la reciente, encontrándose mucho mayor celularidad y atipia en la última. Se efectuaron análisis inmunohistoquímicos con un panel de anticuerpos, que permitió establecer la naturaleza vascular del tumor. El HEE es un tumor muy raro, de crecimiento lento y de bajo potencial metastásico, a pesar de ser de origen vascular. Llama la atención el fenómeno de dependencia hormonal de este tumor, que se plantea en la literatura, y que sugiere otras avenidas terapéuticas.In 1983 an uncommon type of lung tumor was reported in 20 patients, it was then named IVBAT (intravascular, bronchioalveolar tumor. The patients presented with multiple slow growing pulmonary nodules, that ranged microscopically from (apparently benign looking

  18. Many Miles to Go: A Systematic Review of the State of Cost-Utility Analyses in Brazil.

    Science.gov (United States)

    Campolina, Alessandro G; Rozman, Luciana M; Decimoni, Tassia C; Leandro, Roseli; Novaes, Hillegonda M D; De Soárez, Patrícia Coelho

    2017-04-01

    Little is known about the quality and quantity of cost-utility analyses (CUAs) in Brazil. The objective of this study was to provide a systematic review of published CUAs of healthcare technologies in Brazil. We performed a systematic review of economic evaluations studies published in MEDLINE, EMBASE, LILACS (Latin American and Caribbean Health Sciences Literature), SciELO (Scientific Electronic Library Online), NHS EED (National Health Service Economic Evaluation Database), HTA (Health Technology Assessment) Database, Web of Science, Scopus, Bireme (Biblioteca Regional de Medicina), BVS ECOS (Health Economics database of the Brazilian Virtual Library of Health), and SISREBRATS (Sistema de Informação da Rede Brasileira de Avaliação de Tecnologias em Saúde [Brazilian Network for the Evaluation of Health Technologies]) from 1980 to 2013. Articles were included if they were CUAs according to the classification devised by Drummond et al. Two independent reviewers screened articles for relevance and carried out data extraction. Disagreements were resolved through discussion or through consultation with a third reviewer. We performed a qualitative narrative synthesis. Of the 535 health economic evaluations (HEEs) relating to Brazil, only 40 were CUAs and therefore included in the analysis. Most studies adhered to methodological guidelines for quality of reporting and 77.5% used quality-adjusted life-years (QALYs) as the health outcome. Of these studies, 51.6% did not report the population used to elicit preferences for outcomes and 45.2% used a specific population such as expert opinion. The preference elicitation method was not reported in 58.1% of these studies. The majority (80.6%) of studies did not report the instrument used to derive health state valuations and no publication reported whether tariffs (or preference weights) were national or international. No study mentioned the methodology used to estimate QALYs. Many published Brazilian cost-utility studies

  19. The effect of obesity on patients with mild chronic obstructive pulmonary disease: results from KNHANES 2010 to 2012

    Directory of Open Access Journals (Sweden)

    Park JH

    2017-02-01

    Full Text Available Ju-Hee Park, Jung-Kyu Lee, Eun Young Heo, Deog Kyeom Kim, Hee Soon Chung Division of Pulmonary and Critical Care Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Republic of Korea Purpose: A low body mass index has been associated with high mortalities in patients with chronic obstructive pulmonary disease (COPD, and studies reveal that obesity aggravates the clinical effects of COPD. We investigated the impact of obesity on patients newly identified with COPD.Patients and methods: This population-based, cross-sectional study, used data from the Korea National Health and Nutrition Examination Survey (KNHANES conducted from 2010 to 2012. Through analyses of data from this survey, we compared concurrent comorbid diseases, symptoms, and lung functions between an obese and nonobese group of patients with COPD.Results: In total, 618 participants were diagnosed with COPD and the average forced expired volume in 1 s (FEV1 was 79.47%±0.69%. Of the total, 30.5% of the subjects were categorized into an obese group. Subjects in the obese group were likely to have metabolic syndrome (P<0.001, hypertension (P=0.02, and a higher number of comorbidities compared to the nonobese group (2.3±0.1 vs 2.0±0.1, P=0.02. In addition, subjects in the obese group showed a lower forced vital capacity (FVC than subjects in the nonobese group, even after adjusting for covariates (average FVC%, 89.32±1.26 vs 92.52%±0.72%, P=0.037. There were no significant differences in the adjusted FEV1% and adjusted FEV1/FVC between the groups.Conclusions: Among subjects newly identified with mild COPD, participants in the obese group had more comorbid conditions and showed a lower FVC compared with subjects in the nonobese group, even after adjustment of covariates. These findings show that a combination of obesity and COPD may be a severe phenotype; therefore, early attention should be paid to obesity for the management of COPD

  20. The dynamic relationship between emotional and physical states: an observational study of personal health records

    Directory of Open Access Journals (Sweden)

    Lee YS

    2017-02-01

    Full Text Available Ye-Seul Lee,1 Won-Mo Jung,1 Hyunchul Jang,2 Sanghyun Kim,2 Sun-Yong Chung,3 Younbyoung Chae1 1Acupuncture and Meridian Science Research Center, College of Korean Medicine, Kyung Hee University, Seoul, 2Mibyeong Research Center, Korean Institute of Oriental Medicine, Daejeon, 3Department of Neuropsychiatry, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea Objectives: Recently, there has been increasing interest in preventing and managing diseases both inside and outside medical institutions, and these concerns have supported the development of the individual Personal Health Record (PHR. Thus, the current study created a mobile platform called “Mind Mirror” to evaluate psychological and physical conditions and investigated whether PHRs would be a useful tool for assessment of the dynamic relationship between the emotional and physical conditions of an individual.Methods: Mind Mirror was used to collect 30 days of observational data about emotional valence and the physical states of pain and fatigue from 20 healthy participants, and these data were used to analyze the dynamic relationship between emotional and physical conditions. Additionally, based on the cross-correlations between these three parameters, a multilevel multivariate regression model (mixed linear model [MLM] was implemented.Results: The strongest cross-correlation between emotional and physical conditions was at lag 0, which implies that emotion and body condition changed concurrently. In the MLM, emotional valence was negatively associated with fatigue (β =-0.233, P<0.001, fatigue was positively associated with pain (β =0.250, P<0.001, and pain was positively associated with fatigue (β =0.398, P<0.001.Conclusion: Our study showed that emotional valence and one’s physical condition negatively influenced one another, while fatigue and pain positively affected each other. These findings suggest that the mind and body interact instantaneously, in

  1. Hypofractionated helical tomotherapy (75 Gy at 2.5 Gy per fraction for localized prostate cancer: long-term analysis of gastrointestinal and genitourinary toxicity

    Directory of Open Access Journals (Sweden)

    Kong M

    2014-04-01

    Full Text Available Moonkyoo Kong,1 Seong Eon Hong,1 Sung-Goo Chang21Department of Radiation Oncology, 2Department of Urology, Kyung Hee University Medical Center, Kyung Hee University School of Medicine, Seoul, Republic of KoreaBackground: This study is a report on the long-term analysis of acute and late toxicities for patients with localized prostate cancer treated with hypofractionated helical tomotherapy.Methods: From January 2008 through August 2013, 70 patients with localized prostate cancer were treated definitively with hypofractionated helical tomotherapy. The helical tomotherapy was designed to deliver 75 Gy in 2.5 Gy per fraction to the prostate gland, 63 Gy in 2.1 Gy per fraction to the seminal vesicles, and 54 Gy in 1.8 Gy per fraction to the pelvic lymph nodes. Incidence rates and predictive factors for radiation toxicities were analyzed retrospectively.Results: The incidences of grades 0, 1, and 2 acute gastrointestinal (GI toxicity were 51.4%, 42.9%, and 5.7%, and those of acute genitourinary (GU toxicity were 7.1%, 64.3%, and 28.6%, respectively. The maximum dose of rectum and bladder V40 and V50 were significant predictive factors for acute GI and GU toxicity. The cutoff value of rectum maximum dose and bladder V40 and V50 by receiver-operating characteristic curves analysis were 76.5 Gy, 17.3%, and 10.2%, respectively. The incidences of grades 0, 1, and 2 late GI toxicity were 82.0%, 14.0%, and 4.0%, and those of late GU toxicity were 18.0%, 56.0%, and 26.0%, respectively. Rectum V70 and bladder V70 and V75 were significant predictive factors for late GI and GU toxicity. The cutoff value of rectum V70 and bladder V70 and V75 by receiver-operating characteristic curves analysis was 2.8%, 2.8%, and 1.0%, respectively.Conclusion: Hypofractionated helical tomotherapy using a schedule of 75 Gy at 2.5 Gy per fraction had favorable acute and late toxicity rates and no serious complication, such as grade 3 or worse toxicity. To minimize radiation

  2. Effect of the different cover crops on the soil moisture in a Hungarian vineyard

    Science.gov (United States)

    Donkó, Ádám; Miglécz, Tamás; Valkó, Orsolya; Deák, Balázs; Kelemen, András; Török, Péter; Tóthmérész, Béla; Drexler, Dóra

    2017-04-01

    in 2015, at two sampling dates (April and June). During sampling the soil moisture content was measured in seven different depths per sampling point in five replicates: 10 cm, 20 cm, 30 cm, 40 cm, 50 cm, 60 cm, and 70 cm. We found significantly lower indices in case of the Lolium perenne treatment compared to the Grass-forb, and Control treatments in 40-70 cm depth. The results are in accordance with the results of previous research, that state that the use of Lolium perenne in the inter-rows can be sustainable in case of at least 7-800 mm precipitation/year, or under irrigated conditions. Among the three species-rich mixtures we have not found significant differences, but the results show that the Grass-forb mixture (with Plantago lanceolata domination) utilized the least moisture from the soil. Literature Donkó Á, Miglécz T, Valkó O, Tóthmérész B, Deák B, Kelemen A, Török P, Zanathy G, Zsigrai Gy, Drexler D (2015): Intercropping experiments in Hungarian vineyards. HUNGARIAN AGRICULTURE RESEARCH. 24 (4): pp. 31-34. (2015) Miglécz T, Valkó O, Török P, Deák B, Kelemen A, Donkó Á, Drexler D, Tóthmérész B: Establishment of three cover crop mixtures in vineyards. SCIENTIA HORTICULTURAE 197: pp. 117-123. (2015)

  3. 2005. aasta arhitektuurivõistlused

    Index Scriptorium Estoniae

    2005-01-01

    Tulemused: Viljandi Metsakalmistu kabel: I - Andres Lember (Male Arhitektid); Tartu Vabaduse sild: I - Stanislav Shulman, Oleg Samohhin (Peterburi, Transmost); Tartu Mõisavahe kvartali hoonestuskava: I .- Ott Kadarik, Villem Tomiste, Mihkel Tüür (Kosmos); Seewaldi ala planeerimine: I - Jüri Martson, Rasmus Reinolt, Ivo-Martin Veelma (Lokomotiiv); Rotermanni kvartali arhitektuurivõistlus: I - Kosmos; aasta betoonehitis 2004: Ülemiste hotell Tallinnas, Martin Aunin; Lasnamäe Jumalaema kirik: I - Oleg Zhemtshugov (AB Z-Projekt), Nikolai Djatko, Jevgeni Kolomenkin; Pärnu vanalinna ja rannapiirkonna tänavakaubanduse inventari ja jäätmejaamade kujundus: I - Peeter Varrak; Kihnu sadamaala planeerimise ja hoonestamise ideevõistlus: I - Siiri Vallner, Kaire Nõmm, Helina Lass, Anna-Liisa Unt (Kavakava); Narva kolledzhi uus hoone: I - Katrin Koov, S. Vallner (Kavakava) ja Indrek Peil (Head Arhitektid); Randvere algkooli hoone: II - Inga Raukas (Arhitektuuriagentuur); Tartu Toomemäe valgustuse ja arhitektuursete väikevormide ideevõistlus: II - K. Koov ja Heidi Urb (Kabvakava) ning Maarja Kask, Ralf Lõoke, Karli Luik (Salto); Metsakalmistu arhitektide kalmeala: I - M. Kask, R. Lõoke; Skoone bastioni ideevõistlus: I - M. Kask, R. Lõoke, K. Luik (Salto); Mahtra talurahvamuuseum: I -Tomomi Hayashi, Hanno Grossschmidt; parim eramu 2004-2005: metallmaja Tabasalus, Muru & Pere; Tallinna loomaaia läänevärav: I - I. Raukas, Monika Löve, Oliver Soomets; parim puitehitis 2005: Naba lasteaed Pirital, arhitektid Vahur Sova, Lauri Saar, sisearhitekt Mari Tosmin; Pae karjääri revitaliseerimine: III - Veronika Valk, Kerli Raamsalu

  4. A telehealth program for self-management of COPD exacerbations and promotion of an active lifestyle: a pilot randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Tabak M

    2014-09-01

    Full Text Available Monique Tabak,1,2 Marjolein Brusse-Keizer,3 Paul van der Valk,3,4 Hermie Hermens,1,2 Miriam Vollenbroek-Hutten1,2 1Telemedicine Group, Roessingh Research and Development, 2Telemedicine Group, University of Twente, 3Department of Pulmonary Medicine, Medisch Spectrum Twente, 4Medical School Twente, Medisch Spectrum Twente, Enschede, the Netherlands Abstract: The objective of this pilot study was to investigate the use of and satisfaction with a chronic obstructive pulmonary disease (COPD telehealth program applied in both primary and secondary care. The program consisted of four modules: 1 activity coach for ambulant activity monitoring and real-time coaching of daily activity behavior, 2 web-based exercise program for home exercising, 3 self-management of COPD exacerbations via a triage diary on the web portal, including self-treatment of exacerbations, and 4 teleconsultation. Twenty-nine COPD patients were randomly assigned to either the intervention group (telehealth program for 9 months or the control group (usual care. Page hits on the web portal showed the use of the program, and the Client Satisfaction Questionnaire showed satisfaction with received care. The telehealth program with decision support showed good satisfaction (mean 26.4, maximum score 32. The program was accessed on 86% of the treatment days, especially the diary. Patient adherence with the exercise scheme was low (21%. Health care providers seem to play an important role in patients' adherence to telehealth in usual care. Future research should focus on full-scale implementation in daily care and investigating technological advances, like gaming, to increase adherence. Keywords: COPD, physical activity, exacerbations, telehealth, self-management

  5. HβE的局部半圆律和Gauss波动%Local semicircle law and Gaussian fluctuation for Hermite β ensemble

    Institute of Scientific and Technical Information of China (English)

    鲍志刚; 苏中根

    2012-01-01

    令β>0,考虑实直线R上服从HβE分布的n个点λ1,λ,….,λn.Dumitriu和Edelman发现了三对角矩阵模型,并证明了规范化经验测度的整体Wigner半圆律.本文将证明当支撑内点处区间长度大于√logn时,其包含的点个数依概率收敛,即局部半圆律成立.并且(0,∞)上点的个数围绕均值n/2正态波动,方差为logn/π2β.结果的证明主要依赖于Valkó和Virág所用的计数表示以及经典鞅方法.%Let β>0 and consider an n-point process λ1, λ2,...,λn from Hermite ft ensemble on the real line R. Dumitriu and Edelman discovered a tri-diagonal matrix model and established the global Wigner semicircle law for normalized empirical measures. In this paper, we prove that the average number of states in a small interval in the bulk converges in probability when the length of the interval is larger than √logn, i,e., local semicircle law holds. And the number of positive states in (0,∞) is proved to fluctuate normally around its mean n/2 with variance like log n/πr2β. The proofs rely largely on the way invented by Valko and Virag of counting states in any interval and the classical martingale argument.

  6. 2005. aasta arhitektuurivõistlused

    Index Scriptorium Estoniae

    2005-01-01

    Tulemused: Viljandi Metsakalmistu kabel: I - Andres Lember (Male Arhitektid); Tartu Vabaduse sild: I - Stanislav Shulman, Oleg Samohhin (Peterburi, Transmost); Tartu Mõisavahe kvartali hoonestuskava: I .- Ott Kadarik, Villem Tomiste, Mihkel Tüür (Kosmos); Seewaldi ala planeerimine: I - Jüri Martson, Rasmus Reinolt, Ivo-Martin Veelma (Lokomotiiv); Rotermanni kvartali arhitektuurivõistlus: I - Kosmos; aasta betoonehitis 2004: Ülemiste hotell Tallinnas, Martin Aunin; Lasnamäe Jumalaema kirik: I - Oleg Zhemtshugov (AB Z-Projekt), Nikolai Djatko, Jevgeni Kolomenkin; Pärnu vanalinna ja rannapiirkonna tänavakaubanduse inventari ja jäätmejaamade kujundus: I - Peeter Varrak; Kihnu sadamaala planeerimise ja hoonestamise ideevõistlus: I - Siiri Vallner, Kaire Nõmm, Helina Lass, Anna-Liisa Unt (Kavakava); Narva kolledzhi uus hoone: I - Katrin Koov, S. Vallner (Kavakava) ja Indrek Peil (Head Arhitektid); Randvere algkooli hoone: II - Inga Raukas (Arhitektuuriagentuur); Tartu Toomemäe valgustuse ja arhitektuursete väikevormide ideevõistlus: II - K. Koov ja Heidi Urb (Kabvakava) ning Maarja Kask, Ralf Lõoke, Karli Luik (Salto); Metsakalmistu arhitektide kalmeala: I - M. Kask, R. Lõoke; Skoone bastioni ideevõistlus: I - M. Kask, R. Lõoke, K. Luik (Salto); Mahtra talurahvamuuseum: I -Tomomi Hayashi, Hanno Grossschmidt; parim eramu 2004-2005: metallmaja Tabasalus, Muru & Pere; Tallinna loomaaia läänevärav: I - I. Raukas, Monika Löve, Oliver Soomets; parim puitehitis 2005: Naba lasteaed Pirital, arhitektid Vahur Sova, Lauri Saar, sisearhitekt Mari Tosmin; Pae karjääri revitaliseerimine: III - Veronika Valk, Kerli Raamsalu

  7. A case of fulminating amebic colitis associated with toxic megacolon

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Kyung Sik; Lee, Joong Suk; Suh, Soo Jhi [Kyung Hee University Hospital. Seoul (Korea, Republic of)

    1985-12-15

    Amebic colitis was common disease in Korea as well as in the world especially frequent in tropical area such as Africa, India and South America. Clinicopathological forms of this condition were ulcerative rectocolitis (95%), typhloappendicitis (3%), ameboma (1.5%), and fulminating colitis with toxic megacolon (0.5%). The fulminating amebic colitis with toxic megacolon was very rare and dangerous condition which was reported by Wruble on 1966. Toxic megacolon was seen in the cases of ulcerative colitis, Crohn's disease, typhoid fever, cholera, and acute bacillary dysentery. Radiological findings of fulminating amebic colitis with toxic megacolon were megacolon, multiple polypoid filling defects, thumbprinting, and cobble stone appearance, which were resemble with ulcerative colitis. The cause of toxic megacolon was not well known, but it has been speculated that this results from transmural disease with destruction of muscle and the myenteric plexus with resultant loss of muscle tone. Authors experienced a case of fulminating amebic colitis with toxic megacolon which was resemble with ulcerative colitis by radiologically at Kyung Hee University Hospital and reported it with review of the literatures.

  8. 辅助材料

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    乳胶漆用水溶性增稠组合物:KR179662[韩国专利]/韩国:Korea Chemical Co.,Ltd.(Yoon,Joon Hee),改性石墨粒子和含改性石墨粒子的涂料:JP2005—53752[日本专利公开]/日本:Hitachi Funmatsu Yakin Co.,Ltd.等(Shirahige.Minoru等),共聚物表面活性剂、分散的着色剂组合物、涂料及其制备:US2005—39635[美国专利申请公开]/美国:(Yang,Yong等),高密度混合着色材料:KR175187[韩国专利]/韩国:Samhwa Paints Industries Co..Ltd.(Kim.Chang Kyu),玻璃材料用的防水表面处理剂:KR148069[韩国专利]/韩国:KIST(Jung,Ⅲ Nam等),轻金属合金用的防腐蚀剂及其应用:WO2004—101692[国际专利申请,德]/德国:Fraunhofer-Gesellschaft zur Foerderung der Angew and ten Forschung e.V.(Wilken,Ralph等)。

  9. Electroweak Structure of Three- and Four-Body Nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Marcucci, Laura Elisa [Old Dominion Univ., Norfolk, VA (United States)

    2000-06-01

    This work reports results for (i) the elastic electromagnetic form factors of the trin- of ucleons; (ii) the nuclear response functions of interest in ~ experiments, 3 He(~e; e 0 ) experiments, at VERSITY excitation energies below the deuteron breakup threshold; (iii) the astrophysical ark S-factor for proton weak capture on 3 He (the hep reaction). The initial and nal using state wave functions are calculated using the correlated hyperspherical harmonics onsisting method, from a realistic Hamiltonian consisting of the Argonne v 18 two-nucleon uclear and Urbana IX three-nucleon interactions. The nuclear electroweak charge and ts. current operators include one- and many-body components. The predicted mag- netic form factor of 3 H, charge form factors and static properties of both 3 H and ntal 3 He, are in satisfactory agreement with the experimental data. However, the po- sition of the zero in the magnetic form factor of 3 He is underpredicted by theory. disintegration The calculated nuclear response functions in 3 He electrodisintegration at thresh- er old are in good agreement with the experimental data, which have however rather s large errors. Finally, the astrophysical S-factor for the hep reaction is predicted ortant ' 4.5 larger than the value adopted in the standard-solar-model, with important consequences for the solar neutrino spectrum measured by the Super-Kamiokande collaboration.

  10. Amperometric urea biosensors based on sulfonated graphene/polyaniline nanocomposite

    Directory of Open Access Journals (Sweden)

    Das G

    2015-08-01

    Full Text Available Gautam Das, Hyon Hee Yoon Department of Chemical and Biological Engineering, Gachon University, Seongnam, Gyeonggi-do, South Korea Abstract: An electrochemical biosensor based on sulfonated graphene/polyaniline nanocomposite was developed for urea analysis. Oxidative polymerization of aniline in the presence of sulfonated graphene oxide was carried out by electrochemical methods in an aqueous environment. The structural properties of the nanocomposite were characterized by Fourier-transform infrared, Raman spectroscopy, X-ray photoelectron spectroscopy, and scanning electron microscopy techniques. The urease enzyme-immobilized sulfonated graphene/polyaniline nanocomposite film showed impressive performance in the electroanalytical detection of urea with a detection limit of 0.050 mM and a sensitivity of 0.85 µA·cm-2·mM-1. The biosensor achieved a broad linear range of detection (0.12–12.3 mM with a notable response time of approximately 5 seconds. Moreover, the fabricated biosensor retained 81% of its initial activity (based on sensitivity after 15 days of storage at 4°C. The ease of fabrication coupled with the low cost and good electrochemical performance of this system holds potential for the development of solid-state biosensors for urea detection. Keywords: electrochemical deposition, sulfonated graphene oxide, urease

  11. Determination of reliability parameters of radioelectronic devices determined by thermal modes

    Directory of Open Access Journals (Sweden)

    A. V. Nikitchuk

    2014-06-01

    Full Text Available Statement of the problem. The reliability is important (and sometimes crucial functional characteristic for RED. So it is necessary to analyze the impact on them of destabilizing external factors - mechanical, temperature, humidity, ionizing radiation. Structural-design elements RED. SCM are the main objects for which you first need to determine the temperature of the ЕЕS and performance reliability. Determination of the temperature of the EES cells and microassemblies. The basic mathematical models are presented to determine the temperatures of the electronic structure elements of cells and microassemblies. Indicators of HEE reliability as a function of their temperature. The value of the operational failure rate of most groups RED calculated by mathematical models. These indicators include: basic failure rate, the rate regime, the coefficients that take into account changes in operational failure rate depending on various factors. Software definition of reliability parameters. The software product allows you to switch from "manual" calculation reliability REDs to a fully automated modeling components. The program is applicable for calculating the reliability and to find a more "sustainable" elements to increase the probability of failure-free operation. Conclusions. Primary tasks performed in the work are listed

  12. Habitabilidad educativa de las escuelas. Marco de referencia para el diseño de indicadores

    Directory of Open Access Journals (Sweden)

    Juan Manuel Hernández Vázquez

    2010-01-01

    Full Text Available Este documento propone el concepto de habitabilidad educativa de la escuela (HEE para contribuir a subsanar la falta de un marco conceptual que apoye la reflexión y el desarrollo de indicadores sobre las condiciones en que operan los servicios educativos en países con extensa pobreza como el nuestro. Comprende la revisión de ocho dimensiones cuya pertinencia se argumenta con base en la revisión de bibliografía internacional sobre las temáticas involucradas. Las ocho dimensiones planteadas incluyen: 1 disponibilidad de instalaciones y equipamiento en la escuela; 2 condiciones físicas de instalaciones y equipamiento; 3 confort físico en el aula; 4 espacio educativo; 5 sustentabilidad de la escuela; 6 higiene y seguridad física en la escuela; 7 accesibilidad de la escuela; y 8 disponibilidad de infraestructura y servicios de apoyo en la zona de asentamiento. Se puede consultar una versión ampliada de este trabajo en www.inee.edu.mx, en la que se propone un instrumento aplicable a las escuelas de secundaria para levantar información que no ha sido captada en aplicaciones de la Secretaría de Educación Pública o del propio Instituto Nacional para la Evaluación de la Educación.

  13. Additional record of Batasio merianiensis (Chaudhuri 1913, a catfish (Teleostei: Bagridae in upper Brahmaputra River drainage in Arunachal Pradesh, India

    Directory of Open Access Journals (Sweden)

    L. Tamang

    2014-05-01

    Full Text Available This paper communicates the extension of the distribution range of Batasio merianiensis in Sille River in the upper Brahmaputra drainage, East Siang District, Arunachal Pradesh. Detailed examinations of the specimens revealed existence of few morphological variations against those reported by Heok Hee Ng in 2009 on the following characteristics: by having a longer preanal (70.4-73.4 vs. 66.3-68.2% SL; a longer prepectoral (25.1-29.3 vs. 21.4-25.7% SL; a longer adipose-fin base (22.0-27.6 vs. 16.9-22.2% SL; a shorter post-adipose distance (11.6-13.4 vs.13.4-15.5% SL; a deeper body at anus (depth 18.3-20.8 vs.15.2-18.4% SL and broader head (width 17.6-20.0 vs.13.5-16.2 % HL. Few additional characters of the fish are included along with brief information on its habitat. The LIPUM, the semi-traditional method of fishing in the river is identified as a major threat to this species.

  14. Effects of Photon Absorption in High Energy Heavy Ion Collisions

    Science.gov (United States)

    Winchell, Joshua; Somanathan, Sidharth; Fries, Ranier

    2014-09-01

    Photons are an important probe of the hot and dense nuclear matter created in high-energy collisions of nuclei at the Relativistic Heavy Ion Collider (RHIC) and the Large Hadron Collider (LHC). Since the mean free path of photons is larger than the size of the fireball of nuclear matter, final state interactions of photons are usually neglected. In light of recent tension between theoretical calculations and data from RHIC and LHC, we study the effect of reabsorption of photons on elliptic flow v2 and on the nuclear modification factor RAA. We consider photons emitted in primary hard collisions and thermal photons from quark-gluon plasma and hot hadron gas. We use the jet-quenching code PPM to simulate the propagation of those photons in a fireball of quark-gluon plasma and hot hadron gas created by collisions of heavy nuclei. For the absorption cross-sections we consider three different approaches: (a) Compton and pair production processes calculated by us in a static approximation, (b) the photon damping rates calculated by Thoma (1995), and (c) absorption rates derived from a recent photon calculation by van Hees et al.

  15. Prioritization of Lesson learned from Fukushima Accident using AHP

    Energy Technology Data Exchange (ETDEWEB)

    Zubair, Muhammad; Park, Sujina; Heo, Gyunyoung [Kyung Hee Univ., Yongin (Korea, Republic of); Zubair, Muhammad [Univ. of Engineering and Technology, Lahore (Pakistan)

    2013-05-15

    Using Analytic Hierarchy Process (AHP) the present research signifies the technical and nontechnical issues of Fukushima accident. The study exposed that besides technical fixes such as enhanced engineering safety features and better siting choices, the critical ingredient for safe operation of nuclear reactors lie in the quality of human training and transparency of the nuclear regulatory process that keeps public interest at the forefront. In this paper a strategy to increase Nuclear Power Plant (NPP) safety has been developed. By using AHP, best alternative to improve safety and to allocate budget for all technical and non-technical factors related with nuclear safety has been investigated. By using AHP a methodology to increase NPP safety has been proposed. With the help of this technique the qualitative aspect of Fukushima accident has been examined by considering experts judgment. The results showed that a lack of regulatory authorities was one of the main causes of accident. So, more budget allocation in this area would be helpful to reduce accidents and to improve nuclear safety. Even if AHP only addresses the qualitative aspect of safety factors, this study can be extended to quantitative evaluation with other tools such as fault trees or crisis trees so that the final results enable data-driven decision-making process, which is on-going project at Kyung Hee University.

  16. Reverse brain drain in South Korea: state-led model.

    Science.gov (United States)

    Yoon, B L

    1992-01-01

    Korea's reverse brain drain (RBD) has been an organized government effort, rather than a spontaneous social phenomenon, in that various policies and the political support of President Park, Chung-Hee were instrumental in laying the groundwork for its success. Particular features of Korea's RBD policies are the creation of a conducive domestic environment (i.e., government-sponsored strategic R & D institution-building, legal, and administrative reforms), and importantly, the empowerment of returnees (via, i.e., exceptionally good maternal benefits, guarantees of research autonomy). President Park played the cardinal role in empowering repatriates at the expense of his own civil bureaucracy, and his capacity for such patronage derived from Korea's bureaucratic-authoritarian political system. Returning scientists and engineers directly benefitted from this political system as well as Park's personal guardianship. For Park, empowerment of returning "brains" was necessary to accomplish his national industrialization plan, thereby enhancing his political legitimacy in domestic politics. An alliance with the R & D cadre was functionally necessary to successfully consolidate strong presidential power, and politically nonthreatening due to the particular form of "pact of domination" in Korea's power structure. RBD in Korea will continue in the near future given Korea's drive for high technology, and the remarkable expansion of local industrial and educational sectors. Korea's future RBD, however, needs to pay closer attention to the following 4 problems: research autonomy; equality issues; skill-based repatriation of technicians and engineers rather than Ph.Ds; and subsidies to small and medium industry for RBD.

  17. Motivation for physical culture as factor of students’ functional state optimization

    Directory of Open Access Journals (Sweden)

    Lachno O.G.

    2015-10-01

    Full Text Available Purpose: to analyze students’ attitude to physical education classes; to compare motivation for physical education of 1 st and 4 th year students. Material: 100 students of 17 - 22 years’ age participated in the research. All they were questioned. Results: In the whole, boys have positive attitude to sport practicing but some of them can have harmful habits. The attitude to sport practicing of most of girls changes with age. It was found that biological age of students significantly exceeds passport age. Biological age of senior students it reduces to some extent, in comparison with junior students. It was also found that in process of studying at HEE students’ motivation for sport practicing changes to positive side. It witnesses about formation of student positive attitude to physical education in general. Conclusions: we have shown that there is a demand in strengthening of motivation for physical culture classes and further formation positive attitude to them with increasing of students’ knowledge about physical education.

  18. Acupuncture Antiarrhythmic Effects on Drug Refractory Persistent Atrial Fibrillation: Study Protocol for a Randomized, Controlled Trial

    Directory of Open Access Journals (Sweden)

    Jimin Park

    2015-01-01

    Full Text Available Background. Atrial fibrillation (AF is the most common form of arrhythmia. Several trials have suggested that acupuncture may prevent AF. However, the efficacy of acupuncture for AF prevention has not been well investigated. Therefore, we designed a prospective, two-parallel-armed, participant and assessor blinded, randomized, sham-controlled clinical trial to investigate acupuncture in persistent AF (ACU-AF. Methods. A total of 80 participants will be randomly assigned to active acupuncture or sham acupuncture groups in a 1 : 1 ratio. Both groups will take the same antiarrhythmic medication during the study period. Patients will receive 10 sessions of acupuncture treatment once a week for 10 weeks. The primary endpoint is AF recurrence rate. Secondary endpoints are left atrium (LA and left atrial appendage (LAA changes in function and volume, and inflammatory biomarker changes. Ethics. This study protocol was approved by the institutional review boards (IRBs of Kyung Hee University Hospital (number 1335-04. This trial is registered with clinicaltrials.gov NCT02110537.

  19. Discriminating between thermal and nonthermal cosmic relic neutrinos through an annual modulation at PTOLEMY

    Science.gov (United States)

    Huang, Guo-yuan; Zhou, Shun

    2016-12-01

    If massive neutrinos are Dirac particles, the proposed PTOLEMY experiment will hopefully be able to discover the cosmic neutrino background via νe+3H →3He+e- with a capture rate of ΓD≈4 yr-1 . Recently, it has been pointed out that right-handed components of Dirac neutrinos could also be copiously produced in the early Universe and become an extra thermal or nonthermal ingredient of cosmic relic neutrinos, enhancing the capture rate to ΓD≈5.1 yr-1 or ΓD≈6.1 yr-1. In this work, we investigate the possibility to distinguish between thermal and nonthermal spectra of cosmic relic neutrinos by measuring the annual modulation of the capture rate. For neutrino masses of 0.1 eV, we find that the amplitude of annual modulation in the standard case is M ≈0.05 %, which will be increased to 0.1% and 0.15% in the presence of additional thermal and nonthermal right-handed neutrinos, respectively. The future detection of such a modulation will be helpful in understanding the Majorana or Dirac nature of massive neutrinos.

  20. Staphylococcus aureus colonization related to severity of hand eczema.

    Science.gov (United States)

    Mernelius, S; Carlsson, E; Henricson, J; Löfgren, S; Lindgren, P-E; Ehricht, R; Monecke, S; Matussek, A; Anderson, C D

    2016-08-01

    Knowledge on Staphylococcus aureus colonization rates and epidemiology in hand eczema is limited. The aim of this study was to clarify some of these issues. Samples were collected by the "glove juice" method from the hands of 59 patients with chronic hand eczema and 24 healthy individuals. Swab samples were taken from anterior nares and throat from 43 of the 59 patients and all healthy individuals. S. aureus were spa typed and analysed by DNA-microarray-based genotyping. The extent of the eczema was evaluated by the hand eczema extent score (HEES). The colonization rate was higher on the hands of hand eczema patients (69 %) compared to healthy individuals (21 %, p eczema (HEES ≥ 13) had a significantly higher S. aureus density on their hands compared to those with milder eczema (HEES = 1 to 12, p = 0.004). There was no difference between patients and healthy individuals regarding colonization rates in anterior nares or throat. spa typing and DNA-microarray-based genotyping indicated certain types more prone to colonize eczematous skin. Simultaneous colonization, in one individual, with S. aureus of different types, was identified in 60-85 % of the study subjects. The colonization rate and density indicate a need for effective treatment of eczema and may have an impact on infection control in healthcare.

  1. HIERRO ELEMENTAL PARA REMOCIÓN DE NÍQUEL, COMÚNMENTE ENCONTRADO EN DRENAJE ÁCIDO DE MINAS

    Directory of Open Access Journals (Sweden)

    Maria A. Liendo

    2011-01-01

    Full Text Available El objetivo de este estudio fue evaluar la remoción del Ni2+ con partículas de hierro comercial, pues este catión se encuentra frecuentemente en los drenajes ácidos de minas (DAM, que es uno de los problemas ambientales más serios en la industria minera que afecta fuentes de aguas naturales. Fueron realizados ensayos en laboratorio con hierro comercial y soluciones sintéticas que contienen Ni2+, para observar tanto la cinética de remoción como los datos de equilibrio. Los resultados, mostraron que estos siguen el modelo de la isoterma de adsorción de Langmuir y que los datos cinéticos se ajustaron con la ecuación del modelo de adsorción de pseudo segundo orden. Se concluye del presente estudio que la remoción de níquel con hierro en estado elemental (HEE es posible y ocurre de manera rápida.

  2. The BigBite Drift Chambers for the Measurement of GE^n at High Q^2 in Hall A

    Science.gov (United States)

    Craver, Brandon

    2006-10-01

    A precision measurement of the electric form factor of the neutron G^nE has been carried out in Jefferson Lab's Hall A for Q^2 values of 1.2 to 3.5 GeV^2 using a highly polarized ^3He target and the quasi-elastic semi-exclusive ^3He(e, e^'n ) reaction. The experiment detected the ejected neutron with an array of scintillators and the scattered electron with the newly commissioned BigBite spectrometer. This new spectrometer has a large angular acceptance (80 msr), complementing the existing 6 msr high-resolution spectrometers, and will enable a new generation of low-rate experiments with lower resolution requirements. A package of three multi-wire drift chambers was constructed in order to allow the spectrometer to operate under high rate conditions and achieve a spatial resolution of 2˜00 μm. Novel construction techniques used for the drift chambers will be discussed. Online results showing chamber performance at raw hit rates up to 20 MHz per plane will be presented.

  3. Differences in the Tongue Features of Primary Dysmenorrhea Patients and Controls over a Normal Menstrual Cycle

    Directory of Open Access Journals (Sweden)

    Jihye Kim

    2017-01-01

    Full Text Available Background. The aims of this study were to investigate the relationships between tongue features and the existence of menstrual pain and to provide basic information regarding the changes in tongue features during a menstrual cycle. Methods. This study was conducted at the Kyung Hee University Medical Center. Forty-eight eligible participants aged 20 to 29 years were enrolled and assigned to two groups according to their visual analogue scale (VAS scores. Group A included 24 females suffering from primary dysmenorrhea (PD caused by qi stagnation and blood stasis syndrome with VAS ≥ 4. In contrast, Group B included 24 females with few premenstrual symptoms and VAS < 4. All participants completed four visits (menses-follicular-luteal-menses phases, and the tongue images were taken by using a computerized tongue image analysis system (CTIS. Results. The results revealed that the tongue coating color value and the tongue coating thickness in the PD group during the menstrual phase were significantly lower than those of the control group (P=0.031 and P=0.029, resp.. Conclusions. These results suggest that the tongue features obtained from the CTIS may serve as a supplementary means for the differentiation of syndromes and the evaluation of therapeutic effect and prognosis in PD. Trial Registration. This trial was registered with Clinical Research Information Service, registration number KCT0001604, registered on 27 August 2015.

  4. Genetic diversity in Populus nigra plantations from west of Iran

    Directory of Open Access Journals (Sweden)

    Afrooz Alimohamadi

    2012-11-01

    Full Text Available In order to adopt strategies for forest conservation and development,it is necessary to estimate the amount and distribution of genetic diversity in existing populations of poplar in Iran. In this study, the genetic diversity between eight stands of Populus nigra established in Kermanshah province was evaluated on the basis of molecular and morphological markers. To amplify microsatellite loci (WPMS09, WPMS16 and WPMS18, DNA extraction from young and fresh leaveswas done. Various conditions of the PCR assay were examined and to evaluate the morphological variation of the morphological characters leaves (consist of 19 traits were measured. In addition, height growth was measured, to evaluate the growth function of the stands in homogeneous conditions. Genetic diversity in termof polymorphic loci was 0%, because three investigated microsatellite loci were monomorphic. The total number of alleles for 3 microsatellite loci was 6 (na = 2, ne = 2, heo = 1, hee = 0.51. Genetic identity based on Nei was 100%, so genetic distance was 0%. The whole sampled trees represented the same thus the genotype. No significant differences between the mean values of all morphological characters and height growth were revealed. Observed genetic similarity gave indication that same ramets had been selected to plant in poplar plantation established in Kermanshah province.These results suggest the need for an initial evaluation of the genetic diversity in selected ramets for planting in plantation to avoid repetition.

  5. Economic feasibility of hay enriched extruded production as a complete diet for equine

    Directory of Open Access Journals (Sweden)

    Kátia Feltre

    2016-04-01

    Full Text Available The present study aimed to evaluate the economic feasibility of production and commercialization project of Hay Enriched Extruded (HEE as a complete diet for horses. The study was based on survey data and quotation activities involving price from the land preparation (repair, planting and fertilization to the processing of the product at the factory (extrusion and marketing. Transportation costs and taxes were also considered. Discounted Cash Flow (30 years was used to calculate the profitability indicator and the Profit and Loss Statement (PLS. Calculations were developed using Microsoft Office Excel® spreadsheets. Three production scenarios were simulated with different consumer prices: Scenario 1 - equivalent to the complete diet, where the ingredients are supplied together, but purchased separately; Scenario 2 - Considering a value 10% higher than the complete diet; Scenario 3 - Considering a value 20% higher than the complete diet. We observed that the project was economically viable in the three suggested scenarios with positive Net Present Value, Internal Rate of Return greater than 9.4% and payback of 11 to 2 years. The results enable us to conclude that the product may be a promising investment for both product quality and ease of use as the rapid return on invested capital.

  6. Medical Imaging for Understanding Sleep Regulation

    Science.gov (United States)

    Wong, Kenneth

    2011-10-01

    Sleep is essential for the health of the nervous system. Lack of sleep has a profound negative effect on cognitive ability and task performance. During sustained military operations, soldiers often suffer from decreased quality and quantity of sleep, increasing their susceptibility to neurological problems and limiting their ability to perform the challenging mental tasks that their missions require. In the civilian sector, inadequate sleep and overt sleep pathology are becoming more common, with many detrimental impacts. There is a strong need for new, in vivo studies of human brains during sleep, particularly the initial descent from wakefulness. Our research team is investigating sleep using a combination of magnetic resonance imaging (MRI), positron emission tomography (PET), and electroencephalography (EEG). High resolution MRI combined with PET enables localization of biochemical processes (e.g., metabolism) to anatomical structures. MRI methods can also be used to examine functional connectivity among brain regions. Neural networks are dynamically reordered during different sleep stages, reflecting the disconnect with the waking world and the essential yet unconscious brain activity that occurs during sleep.[4pt] In collaboration with Linda Larson-Prior, Washington University; Alpay Ozcan, Virginia Tech; Seong Mun, Virginia Tech; and Zang-Hee Cho, Gachon University.

  7. Genetic diversity in Populus nigra plantations from west of Iran

    Directory of Open Access Journals (Sweden)

    Afrooz Alimohamadi

    2012-12-01

    Full Text Available In order to adopt strategies for forest conservation and development, it is necessary to estimate the amount and distribution of genetic diversity in existing populations of poplar in Iran. In this study, the genetic diversity between eight stands of Populus nigra established in Kermanshah province was evaluated on the basis of molecular and morphological markers. To amplify microsatellite loci (WPMS09, WPMS16 and WPMS18, DNA extraction from young and fresh leaveswas done. Various conditions of the PCR assay were examined and to evaluate the morphological variation of the morphological characters leaves (consist of 19 traits were measured. In addition, height growth was measured, to evaluate the growth function of the stands in homogeneous conditions. Genetic diversity in term of polymorphic loci was 0%, because three investigated microsatellite loci were monomorphic. The total number of alleles for 3 microsatellite loci was 6 (na = 2, ne = 2, heo = 1, hee = 0.51. Genetic identity based on Nei was 100%, so genetic distance was 0%. The whole sampled trees represented the same thus the genotype. No significant differences between the mean values of all morphological characters and height growth were revealed. Observed genetic similarity gave indication that same ramets had been selected to plant in poplar plantation established in Kermanshah province. These results suggest the need for an initial evaluation of the genetic diversity in selected ramets for planting in plantation to avoid repetition.  

  8. Development of the Software for 30 inch Telescope Control System at KHAO

    Science.gov (United States)

    Mun, B.-S.; Kim, S.-J.; Jang, M.; Min, S.-W.; Seol, K.-H.; Moon, K.-S.

    2006-12-01

    Even though 30inch optical telescope at Kyung Hee Astronomy Observatory has been used to produce a series of scientific achievements since its first light in 1992, numerous difficulties in the operation of the telescope have hindered the precise observations needed for further researches. Since the currently used PC-TCS (Personal Computer based Telescope Control system) software based on ISA-bus type is outdated, it doesn't have a user friendly interface and make it impossible to scale. Also accumulated errors which are generated by discordance from input and output signals into a motion controller required new control system. Thus we have improved the telescope control system by updating software and modifying mechanical parts. We applied a new BLDC (brushless DC) servo motor system to the mechanical parts of the telescope and developed a control software using Visual Basic 6.0. As a result, we could achieve a high accuracy in controlling of the telescope and use the userfriendly GUI (Graphic User Interface).

  9. Computed tomography of tumors of paranasal sinuses and face

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Sun Wha [Kyung Hee University College of Medicine, Seoul (Korea, Republic of)

    1982-09-15

    The computed tomography can image both bone and soft tissue structures of paranasal sinuses and face and so CT has added an important new dimension to radiological evaluation of disease of paranasal sinuses and face. CT is more accurate method of staging of tumors and essential for therapeutic planning. The author studied 25 cases of proven tumors of paranasal sinuses and face during the period from October 1977 to August 1980 in Kyung Hee University Hospital. The results were as follows: 1. Among 14 females and 11 male, their age range was from 14 years to 65 year. 2. The distribution of tumors were mucocele, squamous cell carcinoma, metastatic carcinoma, meningioma, angiofibroma, Masson's hemangiosarcoma, fibrous dysplasia, neurogenic sarcoma, Schwannoma, hemangioma, epidermoid, transitional cell carcinoma and unknown. 3. Determination of location and extent of mucocele was easily done by CT. Thus in all cases of ethmoid mucocele, chief complaint of exophthalmos could be easily explained by identification of its extension into peripheral fat space of orbit. 4. It is our belief that CT was useful method to determine staging of tumors of paranasal sinuses and was essential in choosing appropriate treatment modality. 5. The contrast enhancement is generally not helpful in pathologic diagnosis of tumors but intracranial extension of tumors are clearly defined by contrast enhancement.

  10. Computed tomographic evaluation of sellar and parasellar tumors

    Energy Technology Data Exchange (ETDEWEB)

    Suh, Ik Jae; Lee, Sun Wha; Eun, Chung Kie; Lim, Jae Hoon; Ahn, Chi Yul [Kyung Hee University Hospital, Seoul (Korea, Republic of)

    1983-03-15

    The advent of computerized cranial tomography made a greater advance in the diagnosis of very wide variety of intracranial lesions. Authors analyzed 58 pathologically proven sellar and parasellar tumors examined at Kyung Hee University Hospital from Oct. 1977 to Jun. 1981 and the results were as follows: 1. The distribution of the tumors is 28 pituitary adenomas, 18 craniopharyngiomas, 5 meningiomas, 4 germinomas, 2 astrocytomas, and 1 sphenoid mucocele. 2. In pituitary adenoma, the precontrast CT scan of tumors appeared as isodensity in 11 cases, mixed density in 8 cases, high density in 6 cases, and low density in 3 cases, and associated with destruction of sellar turcica in 15 cases, calcification in 3 cases, and hydrocephalus in 2 cases. The postcontrast CT scan study revealed 24 cases of contrast enhancement, including 17 case of homogenous and 7 cases of ring or rim enhancement. 3. In craniopharyngioma, the precontrast CT scan of tumors appeared as low density in 12 cases, isodensity in 4 cases and high density in 2 cases and associated with calcification in 16 cases, hydrocephalus in 15 cases and destruction of sellar turcica in 2 cases. The postcontrast CT scan study revealed no enhancement in 10 cases and contrast enhancement in 8 cases including 6 of ring enhancement and 2 heterogenous enhancement.

  11. Culture and Disease Prevention and Control of Rainbow Fish Poecilia reticulata%孔雀鱼的养殖及病害防治

    Institute of Scientific and Technical Information of China (English)

    陈思行

    2002-01-01

    @@孔雀鱼(Poecilia reticulata)隶属于胎鳝科,胎鳝属。雄鱼色彩鲜艳,五彩缤纷,有些个体体表具蓝黑色小圆斑,周围有淡色的环纹,宛如孔雀的尾翎,故称“孔雀鱼”。它的另一特点是,几乎全年均可繁殖,每个月或隔月就能繁殖一次,每次产幼鱼20~100尾不等;子代经4~5个月便性成熟,一对孔雀鱼一年繁殖后代的数量是惊人的,因此有“百万鱼”(millions)之称。孔雀鱼的英文名为Rainbow fish和Guppy,中文译名常称之为“彩虹鱼”或“格比(鱼)”。此外,尚有摩比鱼、虹鳝和水沟鱼(Longkang Hee)的俗名。……

  12. Sensitivity of Saturn's orbit to a hypothetical distant planet

    Science.gov (United States)

    Folkner, William; Jacobson, Robert A.; Park, Ryan; Williams, James G.

    2016-10-01

    Several distant scattered Kuiper belt objects have similar perihelion directions that might be aligned due to the influence an unknown planet well outside the orbit of Neptune (Batygin & Brown, 2016 Astronomical J. 151:22). Such a planet, with a mass up to an order of magnitude larger than the Earth, would affect the rest of the solar system. Saturn, which is well observed from radio range and VLBI observations of the Cassini spacecraft, provides an opportunity to look for these perturbations. An unknown large planet would be expected to affect the orbit of Saturn, but the effect might be partially absorbed in the estimation of parameters used to fit the planetary ephemerides. Ephemeris parameters include the planetary orbital elements, the mass of the Sun and the masses of asteroids that perturb the orbit of Mars. Earlier analysis of the Cassini data showed no effect as suggested by the Modified Newtonian Dynamics theory (Hees et al., 2014 Phys. Rev. D 89:102002). We present an updated Cassini data set, with the accuracy of ranges to Saturn improved through updated estimates of the Cassini spacecraft orbit, and an analysis of the largest possible perturbing distant planet mass consistent with the ranging data.

  13. 朴槿惠政府外交趋向%New Diplomatic Tendencies of Park Geun-hye Administration

    Institute of Scientific and Technical Information of China (English)

    沈定昌

    2013-01-01

    Under the influence of her father Park Chung-hee, South Korean President Park Geun-hye will carry out pragmatic foreign policies which is to continue the strengthening with neighbouring four big nations. However, the priorities will be adjusted to:US, China, Japan and Russia. Park Geun-hye Administration will abandon the tough stance of last ad-ministration and practise the parallel policy of “stress and dialogue” in or-der to defuse the tension between North Korea and South Korea.This is to create a helpful environment for economic growth and new develop-ment.%韩国总统朴槿惠深受其父前总统朴正熙的影响,将大力推行“实用主义”的外交政策,即继续推行前届政府的加强与周边四大国的外交政策,但重点排序调整为美、中、日、俄;变上届政府对朝鲜一味强硬施压做法,用“施压・对话”双轨并行政策,缓和南北关系。以期最大限度地得到有利于经济发展的外部环境,使韩国获得新的发展。

  14. A nanohybrid system for taste masking of sildenafil

    Directory of Open Access Journals (Sweden)

    Lee JH

    2012-03-01

    Full Text Available Ji-Hee Lee1,*, Goeun Choi1,*, Yeon-Ji Oh1, Je Won Park1, Young Bin Choy3, Mung Chul Park1, Yeo Joon Yoon1, Hwa Jeong Lee2, Hee Chul Chang4, Jin-Ho Choy1 1Center for Intelligent Nano-Bio Materials (CINBM, Department of Bioinspired Science and Department of Chemistry and Nano Science, 2Division of Life and Pharmaceutical Sciences and College of Pharmacy, Ewha Womans University, Seoul, Korea; 3Department of Biomedical Engineering, College of Medicine and Institute of Medical and Biological Engineering, Medical Research Center, Seoul National University, Seoul, Korea; 4Global Strategy Center and Pharmaceutical Research Institute, Daewoong Pharmaceutical Co., Ltd., Seoul, Korea*These authors contributed equally to this workAbstract: A nanohybrid was prepared with an inorganic clay material, montmorillonite (MMT, for taste masking of sildenafil (SDN. To further improve the taste-masking efficiency and enhance the drug-release rate, we coated the nanohybrid of SDN–MMT with a basic polymer, polyvinylacetal diethylaminoacetate (AEA. Powder X-ray diffraction and Fourier transform infrared experiments showed that SDN was successfully intercalated into the interlayer space of MMT. The AEA-coated SDN–MMT nanohybrid showed drug release was much suppressed at neutral pH (release rate, 4.70 ± 0.53%, suggesting a potential for drug taste masking at the buccal cavity. We also performed in vitro drug release experiments in a simulated gastric fluid (pH = 1.2 and compared the drug-release profiles of AEA-coated SDN–MMT and Viagra®, an approved dosage form of SDN. As a result, about 90% of SDN was released from the AEA-coated SDN–MMT during the first 2 hours while almost 100% of drug was released from Viagra®. However, an in vivo experiment showed that the AEA-coated SDN–MMT exhibited higher drug exposure than Viagra®. For the AEA-coated SDN–MMT, the area under the plasma concentration–time curve from 0 hours to infinity (AUC0-∞ and maximum

  15. Inhaled indacaterol for the treatment of COPD patients with destroyed lung by tuberculosis and moderate-to-severe airflow limitation: results from the randomized INFINITY study

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    Kim CJ

    2017-05-01

    Full Text Available Cheong-Ju Kim,1 Hyoung-Kyu Yoon,2 Myung-Jae Park,3 Kwang-Ha Yoo,4 Ki-Suck Jung,5 Jeong-Woong Park,6 Seong Yong Lim,7 Jae Jeong Shim,8 Yong Chul Lee,9 Young-Sam Kim,10 Yeon-Mok Oh,11 Song Kim,12 Chul-Gyu Yoo13 1Department of Internal Medicine, National Health Insurance System Ilsan Hospital, Koyang, 2Division of Pulmonology, Department of Internal Medicine, St Mary’s Hospital, College of Medicine, The Catholic University of Korea, 3Division of Respiratory and Critical Care Medicine, Kyung Hee University Hospital, Kyung Hee University, Seoul, 4Department of Internal Medicine, Konkuk University School of Medicine, Gwangjin-gu, 5Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Hallym University Sacred Heart Hospital, Hallym University Medical School, Anyang-si, 6Division of Pulmonary and Allergy Medicine, Gachon University Gil Medical Center, Incheon, 7Division of Pulmonary and Critical Care Medicine, Department of Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 8Department of Internal Medicine, Korea University College of Medicine, Seoul, 9Department of Internal Medicine and Research Center for Pulmonary Disorders, Chonbuk National University Medical School, Jeonbuk, 10Department of Internal Medicine, Yonsei University College of Medicine, 11Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, 12Clinical Development and Medical Affairs, Novartis Korea Ltd., Seoul, 13Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea Background and objective: Pulmonary tuberculosis (TB is a risk factor for chronic obstructive pulmonary disease (COPD; however, few clinical studies have investigated treatment effectiveness in COPD patients with destroyed lung by TB. The Indacaterol effectiveness in COPD patients with Tuberculosis history (INFINITY

  16. Iron oxide-based nanomagnets in nanomedicine: fabrication and applications

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    Meng Meng Lin

    2010-02-01

    chemistry from Korea University in 1998 and a PhD in oriental medicine from Kyung Hee University, Korea, in 2003. He was a Postdoctoral Fellow at the Vascular Medicine Research Unit, Brigham & Women's Hospital, Harvard Medical School, in 2003. He has been working as an instructor at the Harvard Medical School since 2007 and is Vice Director of the International Research Center of Bioscience and Biotechnology, Jungwon University, Korea. His research interests include cells and signal pathways in vascular biology field. Hyuck Kim received a PhD in oriental medicine from Kyung Hee University, Korea, in 2004. He is currently adjunct Professor at the Faculty of Herb Industry, Jungwon University, Korea, and Director of the International Research Center of Bioscience and Biotechnology, Jungwon University, Korea, since 2008. Additionally, he is President of Jein Medical Center since 2006. He is establishing a collaboration with Harvard Medical School on Asian Hybrid Medicine. Mamoun Muhammed received a BSc and MSc from Cairo University, and a PhD from the Royal Institute of Technology in 1975. He is Chairman of the International Committee on Nanostructured Materials since 2005 and is currently Chair Professor, Head of Functional Materials Division at the Royal Institute of Technology, Sweden. He has published over 200 papers, co-edited one book, and has been a guest editor for two special volumes in the Nanostructured Materials Journal. Do Kyung Kim received a PhD in nanobio from the Royal Institute of Technology, Sweden in 2002. He was a Postdoctoral Fellow at the Massachusetts Institute of Technology (MIT, in 2003. He is currently a lecturer in the Institute of Science and Technology in Medicine, Keele University, UK, and Professor at the International Research Center of Bioscience and Biotechnology, Jungwon University, Korea. His research interests include target-oriented drug delivery systems, contrast agents, and quantum dots for nanomedicine.

  17. Biosynthesis, characterization, and antimicrobial applications of silver nanoparticles

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    Singh P

    2015-03-01

    Full Text Available Priyanka Singh,1 Yeon Ju Kim,2 Hina Singh,1 Chao Wang,2 Kyu Hyon Hwang,3 Mohamed El-Agamy Farh,1 Deok Chun Yang1,2 1Department of Oriental Medicinal Material and Processing, 2Graduate School of Biotechnology and Ginseng Bank, College of Life Sciences, Kyung Hee University, Yongin, 3Gyeonggi-Do Agricultural Research & Extension Services, Gyeonggi, Republic of Korea Abstract: In the present study, the strain Brevibacterium frigoritolerans DC2 was explored for the efficient and extracellular synthesis of silver nanoparticles. These biosynthesized silver nanoparticles were characterized by ultraviolet-visible spectrophotometry, which detected the formation of silver nanoparticles in the reaction mixture and showed a maximum absorbance at 420 nm. In addition, field emission transmission electron microscopy revealed the spherical shape of the nanoparticles. The dynamic light scattering results indicated the average particle size of the product was 97 nm with a 0.191 polydispersity index. Furthermore, the product was analyzed by energy dispersive X-ray spectroscopy, X-ray diffraction, and elemental mapping, which displayed the presence of elemental silver in the product. Moreover, on a medical platform, the product was checked against pathogenic microorganisms including Vibrio parahaemolyticus, Salmonella enterica, Bacillus anthracis, Bacillus cereus, Escherichia coli, and Candida albicans. The nanoparticles demonstrated antimicrobial activity against all of these pathogenic microorganisms. Additionally, the silver nanoparticles were evaluated for their combined effects with the commercial antibiotics lincomycin, oleandomycin, vancomycin, novobiocin, penicillin G, and rifampicin against these pathogenic microorganisms. These results indicated that the combination of antibiotics with biosynthesized silver nanoparticles enhanced the antimicrobial effects of antibiotics. Therefore, the current study is a demonstration of an efficient biological synthesis

  18. Testing the Creation of the Universe: The Primordial Helium Abundance

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    R. P. Bauman

    2003-01-01

    Full Text Available Las mediciones de alta precisión de la abundancia primordial de elementos ligeros es una de las pruebas fundamentales del Big Bang. La abundancia primordial de helio, Yp, el cociente de He a H por masa, se determina por las líneas de emisión que se forman durante el proceso de recombinación-decaimiento, He++e- → Heº (nL+hv, seguido de la cascada radiativa. Una prueba definitiva del Big Bang requiere una precisión del 1% o mejor. Yp se mide de los cocientes de intensidades de líneas de recombinación de He I y H I en regiones H II. El cociente de densidad n(He+/n(H+ es proporcional a la intensidad de las líneas observadas y al cociente inverso de los coeficientes de recombinación. Los estudios previos de coeficientes de recombinación de He I suponen que los tripletes y singuletes son diferentes sistemas de cascadas radiativas que se comunican únicamente por colisiones con intercambio de electrones. De hecho, algunos niveles de alto momento angular tienen multiplicidades de espin mixto, lo que lleva a decaiminetos convencionales de dipolo eléctrico que mezclan a los tripletes y singuletes. Presentamos cálculos tentativos de los coeficientes de recombinación de He I a una temperatura de 10,000 K en el “caso B". Se anticipan diferencias de 1% o mayor que pueden afectar la Yp en cantidades cosmológicamente significativas.

  19. Treatment response in relation to subthreshold bipolarity in patients with major depressive disorder receiving antidepressant monotherapy: a post hoc data analysis (KOMDD study

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    Park YM

    2016-05-01

    Full Text Available Young-Min Park,1 Bun-Hee Lee2 1Department of Psychiatry, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, 2Department of Psychiatry, Seoul Eunpyeong Hospital, Seoul, Republic of Korea Background: The aim of this observational study was to determine whether subthreshold bipolarity affects treatment response and remission in patients with major depressive disorder receiving antidepressant (AD monotherapy over a 6-month follow-up period. Methods: Seventy-eight patients with major depressive disorder were stratified into two subgroups according to the presence of subthreshold bipolarity, identified using the Korean version of the Mood Disorder Questionnaire (K-MDQ, which classifies patients as positive for a screening of bipolarity based on the cutoff for the total K-MDQ score (ie, 7 points. They received AD monotherapy such as escitalopram, sertraline, paroxetine, or tianeptine for 6 months. The Beck Depression Inventory (BDI, Hamilton Depression Rating Scale (HAMD, Hamilton Anxiety Scale, and Beck Scale for Suicide Ideation were applied at baseline, 1 week, 3 weeks, 2 months, 3 months, and 6 months. Results: The mean HAMD, BDI, and Beck Scale for Suicide Ideation scores were higher in the bipolarity group than in the nonbipolarity group at 3 weeks. The mean BDI score was also higher in the bipolarity group than in the nonbipolarity group at 6 months. Evaluation of the ratio of improvement for each scale revealed different patterns of percentage changes between the two groups over the 6-month follow-up period. Furthermore, the response and remission rates (as assessed using BDI and HAMD scores were higher in the nonbipolarity group than in the bipolarity group, with the exception of HAMD scores at the 3-week follow-up time point. Conclusion: The findings of this study showed that depressed patients with bipolarity had a worse response to AD monotherapy than did those without bipolarity. Keywords: subthreshold bipolarity

  20. Disparities in prevalence, location, and shape characteristics of colorectal neoplasia between South Korean and U.S. patients.

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    Cha, Jae Myung; Kozarek, Richard A; La Selva, Danielle; Gluck, Michael; Ross, Andrew; Chiorean, Michael; Koch, Johannes; Lin, Otto S

    2015-12-01

    Colon cancer screening is being introduced in many countries, but standard Western screening approaches may not be appropriate for Asian societies if differences in colon cancer epidemiology exist. Comparative analysis of colorectal neoplasia patterns in South Korean and Western subjects has implications for appropriate screening approaches in non-Western societies. The results of concurrent screening colonoscopies performed in average-risk patients 50 to 69 years old in 2 teaching hospitals, Kyung Hee University Hospital (Seoul, South Korea) and Virginia Mason Medical Center (Seattle, Wash), were compared with respect to prevalence, histologic features, anatomic distribution, and shape characteristics of colorectal neoplasia. The U.S. (n = 3460) and South Korean (n = 2193) cohorts were similar with regard to the prevalence of adenomas (28.5% vs 29.8%, respectively, P = .312) and advanced neoplasia (6.4% vs 5.4%, respectively, P = .102), but the proportion of proximal adenomas was greater in the U.S. cohort (62.8% vs 45.9%, P prevalence of adenomas and advanced neoplasia was similar in male patients, but there was a greater prevalence of neoplasia (23.5% vs 18.8%, P = .006) and advanced neoplasia (5.1% vs 2.7%, P prevalence of large flat adenomas in the U.S. cohort was 5 times that of the South Korean cohort (2.6% vs 0.5%, P prevalence of large flat adenomas. South Korean women have a lower prevalence of colorectal neoplasia than Western women. Such disparities suggest that Western screening strategies cannot be directly adopted by other countries, but need to be customized by society. Copyright © 2015 American Society for Gastrointestinal Endoscopy. Published by Elsevier Inc. All rights reserved.

  1. In vitro antioxidant, collagenase inhibition, and in vivo anti-wrinkle effects of combined formulation containing Punica granatum, Ginkgo biloba, Ficus carica, and Morus alba fruits extract

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    Ghimeray AK

    2015-07-01

    Full Text Available Amal Kumar Ghimeray,1 Un Sun Jung,1,2 Ha Youn Lee,1 Young Hoon Kim,1 Eun Kyung Ryu,1 Moon Sik Chang11R&D Center, Natural Solution Co., Ltd, Gojan-dong, Namdong-gu, Incheon, Republic of Korea; 2Department of Horticultural Biotechnology, Kyung Hee University, Yongin, Republic of KoreaBackground: In phytotherapy, the therapeutic potential is based on the combined action of different herbal drugs. Our objective was to evaluate the antioxidant, anti-collagenase (in vitro, and anti-wrinkle (in vivo effect of combined formulation containing Ginkgo biloba, Punica granatum, Ficus carica, and Morus alba fruits extract.Methods: Antioxidant evaluation was based on the scavenging activity of free radicals (1,1-diphenyl-2-picrylhydrazyl, H2O2, and O2- and the anti-collagenase activity was based on the reduction of collagenase enzyme in vitro. In an in vivo study, 21 female subjects were examined in a placebo-controlled trail. Facial wrinkle, especially the crow's feet region of eyes, was treated with topical formulated 2% cream for 56 days and compared with the placebo.Results: In the in vitro study, the combination of fruits extract showed a higher antioxidant activity which was comparable with the positive standard (ascorbic acid, butylated hydroxyanisole, and Trolox. The data also showed a dose-dependent inhibition of collagenase. In the in vivo study, treatment with 2% formulated cream for 56 days significantly reduced the percentage of wrinkle depth, length, and area with 11.5, 10.07, and 29.55, respectively.Conclusion: The combined formulation of fruit extracts showed excellent antioxidative and anti-collagenase activity as well as a significant effect on anti-wrinkle activity on human skin.Keywords: antioxidant, anti-collagenase, anti-wrinkle, fruits, topical formulation

  2. Primary percutaneous coronary intervention ameliorates complete atrioventricular block complicating acute inferior myocardial infarction

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    Lee SN

    2014-11-01

    Full Text Available Su Nam Lee, You-Mi Hwang, Gee-Hee Kim, Ji-Hoon Kim, Ki-Dong Yoo, Chul-Min Kim, Keon-Woong MoonDepartment of Internal Medicine, St Vincent’s Hospital, The Catholic University of Korea, Suwon, South KoreaObjective: Complete atrioventricular block (CAVB in acute inferior ST-segment elevation myocardial infarction (STEMI is associated with poor clinical outcomes after noninvasive treatment. This study was designed to determine the effect of primary percutaneous coronary intervention (PCI in patients with CAVB complicating acute inferior STEMI, at a single center.Methods: We enrolled 138 consecutive patients diagnosed with STEMI involving the inferior wall; of these, 27 patients had CAVB. All patients received primary PCI. The clinical characteristics, procedural data, and clinical outcomes were compared in patients with versus without CAVB. Results: Baseline clinical characteristics were similar between patients with and without CAVB. Patients with CAVB were more likely to present with cardiogenic shock, and CAVB was caused primarily by right coronary artery occlusion. Door-to-balloon time was similar between those two groups. After primary PCI, CAVB was reversed in all patients. The peak creatinine phosphokinase level, left ventricular ejection fraction and in-hospital mortality rate were similar between the two groups. After a median follow up of 318 days, major adverse cardiac events did not differ between the groups (8.1% in patients without CAVB; 11.1% in patients with CAVB (P=0.702.Conclusion: We conclude that primary PCI can ameliorate CAVB-complicated acute inferior STEMI, with an acceptable rate of major adverse cardiac events, and suggest that primary PCI should be the preferred reperfusion therapy in patients with CAVB complicating acute inferior myocardial infarction. Keywords: major adverse cardiac events, PCI-capable hospital

  3. Lurasidone as a potential therapy for bipolar disorder

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    Woo YS

    2013-10-01

    Full Text Available Young Sup Woo, Hee Ryung Wang, Won-Myong Bahk Department of Psychiatry, Yeouido St Mary's Hospital, The Catholic University of Korea, Seoul, Korea Abstract: Lurasidone is a benzisothiazol derivative and an atypical antipsychotic approved by the US Food and Drug Administration for the acute treatment of adults with schizophrenia (October 2010 and bipolar 1 depression (June 2013. Lurasidone has a strong antagonistic property at the D2, serotonin (5-HT2A, and 5-HT7 receptors, and partial agonistic property at the 5-HT1A receptor. Lurasidone also has lower binding affinity for the α2C and 5-HT2C receptor. Lurasidone is rapidly absorbed (time to maximum plasma concentration: 1–3 hours, metabolized mainly by CYP3A4 and eliminated by hepatic metabolism. In two large, well-designed, 6-week trials in adult patients with bipolar 1 depression, lurasidone monotherapy and adjunctive therapy with mood stabilizers were significantly more effective than placebo at improving depressive symptoms assessed using the Montgomery–Åsberg Depression Rating Scale total score. In both trials, lurasidone also reduced the Clinical Global Impression–Bipolar Severity depression score to a greater extent than placebo. In these two trials, discontinuation rates due to adverse events in the lurasidone group were small (<7% and were not different from those of the placebo group. The most common adverse events in the lurasidone group were headache, nausea, somnolence, and akathisia. The changes in lipid profiles, weight, and parameters of glycemic control were minimal, and these findings were in line with those observed in schizophrenia trials. Further active comparator trials and long-term tolerability and safety data in bipolar patients are required. Lurasidone may be an option for the management of depressive symptoms in patients with bipolar 1 disorder, and it may be considered as a treatment alternative for patients who are at high risk for metabolic abnormalities

  4. Study on Bee venom and Pain

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    Hyoung-Seok Yun

    2000-07-01

    Full Text Available In order to study Bee venom and Pain, We searched Journals and Internet. The results were as follows: 1. The domestic papers were total 13. 4 papers were published at The journal of korean acupuncture & moxibustion society, 3 papers were published at The journal of korean oriental medical society, Each The journal of KyoungHee University Oriental Medicine and The journal of korean sports oriental medical society published 1 papers and Unpublished desertations were 3. The clinical studies were 4 and the experimental studies were 9. 2. The domestic clinical studies reported that Bee venom Herbal Acupuncture therapy was effective on HIVD, Subacute arthritis of Knee Joint and Sequale of sprain. In the domestic experimental studies, 5 were related to analgesic effect of Bee vnom and 4 were related to mechanism of analgesia. 3. The journals searched by PubMed were total 18. 5 papers were published at Pain, Each 2 papers were published at Neurosci Lett. and Br J Pharmacol, and Each Eur J Pain, J Rheumatol, Brain Res, Neuroscience, Nature and Toxicon et al published 1 paper. 4. In the journals searched by PubMed, Only the experimental studies were existed. 8 papers used Bee Venom as pain induction substance and 1 paper was related to analgesic effects of Bee venom. 5. 15 webpage were searched by internet related to Bee Venom and pain. 11 were the introduction related to arthritis, 1 was the advertisement, 1 was the patient's experience, 1 was the case report on RA, 1 was review article.

  5. A radiologic study of dentigerous cysts

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    Choi, Moon Cheol; Lee, Sang Rae [Department of Dental Radiology, Division of Dentistry, Kyung Hee University, Seoul (Korea, Republic of)

    1984-11-15

    The purpose of the present study is to offer the fundamental materials for the diagnosis of dentigerous cyst by analysis of the clinical and radiographic finding of these lesions. The subject for this study consisted 118 patients admitted to the Department of Oral Radiology, Kyung Hee University and Seoul National University from 1974 to 1983. Conclusions from this study were as follows: 1. There was a higher incidence in males (70.34%) than in females (29.66%), and the incidence was highest in the second and third decade (26.27%) with the same incidence. (Average age: 25 year) 2. There was a higher incidence in the maxillary teeth (66.10%) than in the mandibular teeth (33.90%) and the maxillary supernumerary tooth (45.76%) was the most frequently involved one. The mandibular third molar (16.10%) was next in order of frequency of involvement followed by maxillary canine (7.63%) , mandibular second premolar (5.08%). 3. There was a greater incidence of the central type than the lateral type in the maxilla, while a higher incidence of the lateral type in the mandible. 4. There was a greater incidence of the smooth type (84.26%) than that of the scalloped type (15.74%) and a higher incidence of minor type (70.91%) than the major type (29.09%) in the displacement of associated tooth. 5. Root apices of teeth encompassed or approached by the cysts showed variable resorption in 68.47% of cases.

  6. PREFACE: International Conference on Advancement in Science and Technology 2012 (iCAST): Contemporary Mathematics, Mathematical Physics and their Applications

    Science.gov (United States)

    Ganikhodjaev, Nasir; Mukhamedov, Farrukh; Hee, Pah Chin

    2013-04-01

    The 4th International Conference on the Advancement of Science and Technology 2012 (iCAST 2012), with theme 'Contemporary Mathematics, Mathematical Physics and their Applications', took place in Kuantan, Malaysia, from Wednesday 7 to Friday 9 November 2012. The conference was attended by more than 100 participants, and hosted about 160 oral and poster papers by more than 140 pre-registered authors. The key topics of the 4th iCAST 2012 include Pure Mathematics, Applied Mathematics, Theoretical/Mathematical Physics, Dynamical Systems, Statistics and Financial Mathematics. The scientific program was rather full since after the Keynote and Invited Talks in the morning, four parallel sessions ran every day. However, according to all attendees, the program was excellent with a high level of talks and the scientific environment was fruitful; thus all attendees had a creative time. The conference aimed to promote the knowledge and development of high-quality research in mathematical fields concerned with the application of other scientific fields as well as modern technological trends in physics, chemistry, biology, medicine, economics, sociology and environmental sciences. We would like to thank the Keynote and the Invited Speakers for their significant contributions to 4th iCAST 2012. We would also like to thank the members of the International Scientific Committee and the members of the Organizing Committee. We cannot end without expressing our many thanks to International Islamic University Malaysia and our sponsors for their financial support . This volume presents selected papers which have been peer-reviewed. The editors hope that it may be useful and fruitful for scholars, researchers, and advanced technical members of the industrial laboratory facilities for developing new tools and products. Guest Editors Nasir Ganikhodjaev, Farrukh Mukhamedov and Pah Chin Hee The PDF contains the committee lists, board list and biographies of the plenary speakers.

  7. The Experience of Human Milk Banking for 8 Years: Korean Perspective.

    Science.gov (United States)

    Jang, Hye Lim; Cho, Jung Yoon; Kim, Mi Jin; Kim, Eun Jeong; Park, Eun Young; Park, Sung Ae; Kim, In Young; Choi, Yong Sung; Bae, Chong Woo; Chung, Sung Hoon

    2016-11-01

    Human milk banks are a solution for mothers who cannot supply their own breast milk to their sick or hospitalized infants; premature infants, in particular, are unable to receive a full volume of breast milk for numerous reasons. As of December 2015, there was only one milk bank in a university hospital in Korea. We reviewed the basic characteristics of donors and recipients, and the amounts and contamination of breast milk donated at the Human Milk Bank in Kyung Hee University Hospital at Gangdong in Korea from 2008 to 2015. The donor pool consisted of 463 first-time donors and 452 repeat donors who made 1,724 donations. A total of 10,820 L of breast milk was collected, and 9,541.6 L were processed. Detectable bacteria grew in 12.6% after pasteurization and 52.5% had cytomegalovirus DNA before pasteurization in donated milk. There were 836 infant and 25 adult recipients; among new infant recipients, 48.5% were preterm; the groups received 8,009 and 165.7 L of donor milk, respectively. There was an increase in the percentage of preterm infants among new infant recipients in 2015 (93.1%) compared to 2008 (8.5%). Based on the number of premature infants in Korea, the number of potential recipients is not likely to diminish anytime soon, despite efforts to improve the breastfeeding rate. Sustainability and quality improvement of the milk bank need long-term financial support by health authorities and a nationwide network similar to blood banking will further contribute to the progress of milk banking.

  8. Spotlight on nano-theranostics in South Korea: applications in diagnostics and treatment of diseases

    Directory of Open Access Journals (Sweden)

    Lee S

    2015-08-01

    Full Text Available Sangwha Lee,1,* Jongsung Kim,1,* Chung Wung Bark,2 Bonghee Lee,3 Heongkyu Ju,4 Se Chan Kang,5 TaeYoung Kim,6 Moon Il Kim,6 Young Tag Ko,3 Jeong-Seok Nam,3 Hyon Hee Yoon,1 Kyu-Sik Yun,1,6 Young Soo Yoon,1 Seong Soo A An,1,6 John Hulme6 1BioNano Sensor Research Center, 2Department of Electrical Engineering, Gachon University, Seongnam-si, 3Lee Gil Ya Cancer and Diabetes Institute, Gachon University, Incheon, 4Department of Nano-Physics, 5Department of Life Science, Gachon University, 6Department of BioNano Technology, Gachon BioNano Research Institute, Seongnam-si, South Korea *These authors contributed equally to this work Abstract: From the synergistic integration and the multidisciplinary strengths of the BioNano Sensor Research Center, Gachon Bionano Research Institute, and Lee GilYa Cancer and Diabetes Institute, researchers, students, and faculties at Gachon University in collaboration with other institutions in Korea, Australia, France, America, and Japan have come together to produce a special issue on the diverse applications of nano-theranostics in nanomedicine. This special issue will showcase new research conducted by various scientific groups in Gyonggi-do and Songdo/Incheon, South Korea. The objectives of this special issue are as follows: 1 to bring together and demonstrate some of the latest research results in the field, 2 to introduce new multifunctional nanomaterials and their applications in imaging and detection methods, and 3 to stimulate collaborative interdisciplinary research at both national and international levels in nanomedicine. Keywords: cancer, imaging and therapeutics, antibacterial, disease, neurodegenerative

  9. Experiments on thermo-hydro-mechanical behaviour of Opalinus Clay at Mont Terri rock laboratory, Switzerland

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    Paul Bossart

    2017-06-01

    Full Text Available Repositories for deep geological disposal of radioactive waste rely on multi-barrier systems to isolate waste from the biosphere. A multi-barrier system typically comprises the natural geological barrier provided by the repository host rock – in our case the Opalinus Clay – and an engineered barrier system (EBS. The Swiss repository concept for spent fuel and vitrified high-level waste (HLW consists of waste canisters, which are emplaced horizontally in the middle of an emplacement gallery and are separated from the gallery wall by granular backfill material (GBM. We describe here a selection of five in-situ experiments where characteristic hydro-mechanical (HM and thermo-hydro-mechanical (THM processes have been observed. The first example is a coupled HM and mine-by test where the evolution of the excavation damaged zone (EDZ was monitored around a gallery in the Opalinus Clay (ED-B experiment. Measurements of pore-water pressures and convergences due to stress redistribution during excavation highlighted the HM behaviour. The same measurements were subsequently carried out in a heater test (HE-D where we were able to characterise the Opalinus Clay in terms of its THM behaviour. These yielded detailed data to better understand the THM behaviours of the granular backfill and the natural host rock. For a presentation of the Swiss concept for HLW storage, we designed three demonstration experiments that were subsequently implemented in the Mont Terri rock laboratory: (1 the engineered barrier (EB experiment, (2 the in-situ heater test on key-THM processes and parameters (HE-E experiment, and (3 the full-scale emplacement (FE experiment. The first demonstration experiment has been dismantled, but the last two ones are on-going.

  10. Peer supporter experiences of home visits for people with HIV infection

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    Lee HJ

    2015-09-01

    Full Text Available Han Ju Lee,1 Linda Moneyham,2 Hee Sun Kang,3 Kyung Sun Kim41Department of Nursing, Sangmyung University, Cheonan-si, Chungcheongnam-do, South Korea; 2School of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA; 3Red Cross College of Nursing, Chung-Ang University, Seoul, South Korea; 4Gyeonggi Branch, Korean Alliance to Defeat AIDS, Anyang, Gyeonggi-do, South KoreaPurpose: This study's purpose was to explore the experiences of peer supporters regarding their work in a home visit program for people with HIV infection.Patients and methods: A qualitative descriptive study was conducted using focus groups. Participants were 12 HIV-positive peer supporters conducting home visits with people living with HIV/AIDS in South Korea. Thematic analysis was used to analyze the data.Results: Six major themes emerged: feeling a sense of belonging; concern about financial support; facing HIV-related stigma and fear of disclosure; reaching out and acting as a bridge of hope; feeling burnout; and need for quality education. The study findings indicate that although peer supporters experience several positive aspects in the role, such as feelings of belonging, they also experience issues that make it difficult to be successful in the role, including the position's instability, work-related stress, and concerns about the quality of their continuing education.Conclusion: The findings suggest that to maintain a stable and effective peer supporter program, such positions require financial support, training in how to prevent and manage stress associated with the role, and a well-developed program of education and training.Keywords: human immunodeficiency virus, qualitative research, workplace experience

  11. Photothermal cancer therapy using graphitic carbon–coated magnetic particles prepared by one-pot synthesis

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    Lee HJ

    2014-12-01

    Full Text Available Hyo-Jeong Lee,1 Jakkid Sanetuntikul,2 Eun-Sook Choi,1 Bo Ram Lee,1 Jung-Hee Kim,1 Eunjoo Kim,1 Sangaraju Shanmugam2 1Nano and Bio Research Division, 2Department of Energy Systems Engineering, Daegu Gyeongbuk Institute of Science and Technology, Daegu, Republic of Korea Abstract: We describe here a simple synthetic strategy for the fabrication of carbon-coated Fe3O4 (Fe3O4@C particles using a single-component precursor, iron (III diethylenetriaminepentaacetic acid complex. Physicochemical analyses revealed that the core of the synthesized particles consists of ferromagnetic Fe3O4 material ranging several hundred nanometers, embedded in nitrogen-doped graphitic carbon with a thickness of ~120 nm. Because of their photothermal activity (absorption of near-infrared [NIR] light, the Fe3O4@C particles have been investigated for photothermal therapeutic applications. An example of one such application would be the use of Fe3O4@C particles in human adenocarcinoma A549 cells by means of NIR-triggered cell death. In this system, the Fe3O4@C can rapidly generate heat, causing >98% cell death within 10 minutes under 808 nm NIR laser irradiation (2.3 W cm-2. These Fe3O4@C particles provided a superior photothermal therapeutic effect by intratumoral delivery and NIR irradiation of tumor xenografts. These results demonstrate that one-pot synthesis of carbon-coated magnetic particles could provide promising materials for future clinical applications and encourage further investigation of this simple method. Keywords: graphitic carbon–encapsulated magnetic nanoparticles, iron oxide, one-pot synthesis, photothermal cancer therapy

  12. Color transparency after the NE18 and E665 experiments: Outlook and perspectives at CEBAF

    Energy Technology Data Exchange (ETDEWEB)

    Nemchik, J. [Inst. of Experimental Physicals, Kosice (Czechoslovakia); Nikolaev, N.N.; Zakharov, B.G. [L.D. Landau Inst. for Theoretical Physics, Moscow (Russian Federation)

    1994-04-01

    CEBAF is a high-luminocity factory of virtual photons with variable virtuality Q{sup 2} and transverse size. This makes CEBAF, in particular after the energy upgrade to (8-12)GeV, an ideal facility for uncovering new phenomena, and opening new windows, at the interface of the perturbative and nonperturbative QCD. The authors discuss color transparency as the case for a broad program on electroproduction of vector mesons {rho}{sup 0}, {omega}{sup 0}, {phi}{sup 0} and their radial excitations {rho}{prime}, {omega}{prime}, {phi}{prime} at CEBAF. They also comment on the second generation of experiments on color transparency in {sup 4}He(e, e{prime}p) scattering, which are also feasible at CEBAF. In 1994, they can make more reliable projections into future because their understanding of the onset of color transparency has greatly been augmented by two experiments completed in 1993: (i) no effect of CT was seen in the SLAC NE18 experiment on A(e, e{prime}p) scattering at virtualities of the exchanged photon Q{sup 2} {approx_lt} 7 GeV{sup 2}, (ii) strong signal of CT was observed in the FNAL E665 experiment on exclusive {rho}{sup 0}-meson production in deep inelastic scattering in the same range of Q{sup 2}. They discuss the impact of these observations on the CEBAF experimental program. They argue they both are good news, both were anticipated theoretically, and both rule in the correct QCD mechanism of the onset of CT.

  13. Oxidative stress by layered double hydroxide nanoparticles via an SFK-JNK and p38-NF-κB signaling pathway mediates induction of interleukin-6 and interleukin-8 in human lung epithelial cells

    Directory of Open Access Journals (Sweden)

    Choi SJ

    2015-04-01

    Full Text Available Soo-Jin Choi, Hee-Jeong Paek, Jin YuDepartment of Food Science and Technology, Seoul Women’s University, Seoul, Republic of KoreaAbstract: Anionic nanoclays are layered double hydroxide nanoparticles (LDH-NPs that have been shown to exhibit toxicity by inducing reactive oxidative species and a proinflammatory mediator in human lung epithelial A549 cells. However, the molecular mechanism responsible for this LDH-NP-induced toxicity and the relationship between oxidative stress and inflammatory events remains unclear. In this study, we focused on intracellular signaling pathways and transcription factors induced in response to oxidative stress caused by exposure to LDH-NPs in A549 cells. Mitogen-activated protein kinase (MAPK cascades, such as extracellular signal-regulated kinase, c-Jun-N-terminal kinase (JNK, and p38, were investigated as potential signaling mechanisms responsible for regulation of oxidative stress and cytokine release. Src family kinases (SFKs, which are known to mediate activation of MAPK, together with redox-sensitive transcription factors, including nuclear factor kappa B and nuclear factor-erythroid 2-related factor-2, were also investigated as downstream events of MAPK signaling. The results obtained suggest that LDH-NP exposure causes oxidative stress, leading to expression of antioxidant enzymes, such as catalase, glucose reductase, superoxide dismutase, and heme oxygenase-1, via a SFK-JNK and p38-nuclear factor kappa B signaling pathway. Further, activation of this signaling was also found to regulate release of inflammatory cytokines, including interleukin-6 and interleukin-8, demonstrating the inflammatory potential of LDH-NP.Keywords: layered double hydroxide, mitogen-activated protein kinases, Src family kinases, nuclear factor kappa B, oxidative stress, inflammatory cytokine

  14. Aberrant brain-stem morphometry associated with sleep disturbance in drug-naïve subjects with Alzheimer's disease

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    Lee JH

    2016-08-01

    Full Text Available Ji Han Lee,1 Won Sang Jung,2 Woo Hee Choi,3 Hyun Kook Lim4 1Washington University in St Louis, St Louis, MO, USA; 2Department of Radiology, 3Department of Nuclear Medicine, 4Department of Psychiatry, Saint Vincent Hospital, College of Medicine, The Catholic University of Korea, Suwon, South Korea Objective: Among patients with Alzheimer’s disease (AD, sleep disturbances are common and serious noncognitive symptoms. Previous studies of AD patients have identified deformations in the brain stem, which may play an important role in the regulation of sleep. The aim of this study was to further investigate the relationship between sleep disturbances and alterations in brain stem morphology in AD.Materials and methods: In 44 patients with AD and 40 healthy elderly controls, sleep disturbances were measured using the Neuropsychiatry Inventory sleep subscale. We employed magnetic resonance imaging-based automated segmentation tools to examine the relationship between sleep disturbances and changes in brain stem morphology.Results: Analyses of the data from AD subjects revealed significant correlations between the Neuropsychiatry Inventory sleep-subscale scores and structural alterations in the left posterior lateral region of the brain stem, as well as normalized brain stem volumes. In addition, significant group differences in posterior brain stem morphology were observed between the AD group and the control group.Conclusion: This study is the first to analyze an association between sleep disturbances and brain stem morphology in AD. In line with previous findings, this study lends support to the possibility that brain stem structural abnormalities might be important neurobiological mechanisms underlying sleep disturbances associated with AD. Further longitudinal research is needed to confirm these findings. Keywords: Alzheimer’s disease, sleep, brain stem, MRI, shape analysis

  15. Masterplan, Creative Zone Beijing, China%北京创意园区整体规划

    Institute of Scientific and Technical Information of China (English)

    吴春花

    2011-01-01

    客户北京市延庆区人民政府规划与建筑设计UNStudio:Ben van Berkel,Caroline Bos with Markus van Aalderen,Yi Cheng Pan and Mieneke Dijkema,Ren Yee,Clarissa Alfrink,Megan Ng,Maud van Hees,Wendy van der Knijff,Jae Young Lee 基地面积210 152m2建筑面积145 119m2城市发展顾问dcu,Pablo Vaggione可持续设计顾问Arup工程顾问(上海)有限公司"于自然中的都市"这一主题旨在保护延庆当地的自然特征,同时容纳一定的城市生活,整个设计将绿带与城市肌理两个尺度结合起来.通过对城市肌理的浓缩,创造出一个高度编织和紧密的城市环境,从而在城市与自然之间既形成清晰的界限又具有紧凑性.两个不同但相互联系的创意产业带和基础设施带相互编织成边缘地带的城市组织,同时营造了从街道到庭院到公共广场的一系列连续的开放空间.浓缩景观最大限度地扩展了绿带,增加的绿带和公园为创意人士工作、组织活动以及画室和亭、阁的娱乐活动提供了绿色环境.

  16. On Governments Responsibility in Running Schools for Privately- run Higher Education Institution%民办高等教育机构办学中的政府责任

    Institute of Scientific and Technical Information of China (English)

    魏冰玲

    2012-01-01

    民办高等教育机构在办学中会遇到各种风险,为有效保障利益相关者的权益,应从风险与监管问题出发,着重解决民办高校办学中面临的风险。政府在解决这一问题的过程中,扮演着重要的领导者和监督者责任。政府应从风险评估、风险预测和构建风险预防系统的途径着手,通过科学的引导办法和系统的监督体系,来实现民办高等教育机构的安全健康发展。政府可以从国外办学和民办教育历史改革中吸取经验和教训,从而减少规划成本和降低风险成本,实现资源的最优化配置。%The privately- run colleges encounter in a variety of risks in running schools. To effectively safe- guard the interests of stakeholders, we should start from risk and supervision and focus on solving the risks they face. The construction of the risk prevention system for privately - run colleges becomes the actual demand of pro- moting the sustainable and hee.lthy development of privately - run higher education at present. Government has an inescapable responsibility about it. It is the most important and most compelling content to implement scientific and optimize the environment of running schools, perfect regulations and policies, increase financial support and stand- ardize the way they operate.

  17. The effect of radiation therapy on hemophilic arthropathy

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Jin Oh; Hong, Seong Eon; Kim, Sang Gi; Shin, Dong Oh [School of Medicine, KyungHee University, Seoul (Korea, Republic of)

    2005-06-15

    Repetitive bleeding into the joint space is the cause of debilitative hemophilic arthropathy. To interrupt this process, we treated the hemophilic patients suffering from repetitive joint bleeding with radiation therapy. From 1997 to 2001, a total of 41 joints from 37 hemophilic arthropathy patients were treated with radiation therapy at KyungHee University Hospital. The treated joints were 35 ankles, 3 knees and 3 elbows, respectively. The age of the patients ranged from 4 to 27 years (median age: 11 years). The radiation dose ranged from 900 cGy to 2360 cGy (median dose: 900 cGy). The fraction size was 150 cGy, 180 cGy or 200 cGy. The number of bleeding in one year before and after radiotherapy was compared. There was a tendency of frequent bleeding for the patients younger than 11 ({rho} 0.051) but there was also a tendency for more improvement in this group ({rho} 0.057). The number of joint bleedings was related with joint pain ({rho} 0.012) and joint swelling ({rho} = 0.033) but not with the Arbold-Hilgartner stage ({rho} 0.739),cartilage destruction ({rho} = 0.718) and synovial hypertrophy ({rho} = 0.079). The number of bleeding was reduced in thirty-three cases, and eight cases showed no improvement after radiation therapy. The average number of bleeding in a month was 2.52 before radiotherapy, but this was reduced to 1.4 after radiotherapy ({rho} = 0.017). Radiation therapy was effective for the hemophilia patients with repetitive joint bleeding to decrease the bleeding frequency and to prevent hemophilic arthropathy.

  18. Usefulness of the retromandibular transparotid approach for condylar neck and condylar base fractures.

    Science.gov (United States)

    Kim, Bae-Kyung; Kwon, Yong-Dae; Ohe, Joo Young; Choi, Yong-Ha; Choi, Byung-Joon

    2012-05-01

    Condyle fractures represent 20% to 30% of all mandibular fractures and are thus among the most common facial fractures. The fracture pattern can vary greatly and may occur anywhere along the line from the sigmoid notch to the mandibular angle. The main problems are access, difficulty in repositioning the extremely slender fragments, and fixation of the condyle.Eighty-seven patients were diagnosed with condylar neck or condylar base fractures from January 2007 to December 2009 in the Department of Oral & Maxillofacial Surgery of Kyung Hee University Dental Hospital. In this study, we included 35 patients who underwent open surgery and a total of 28 patients who were treated using a retromandibular transparotid approach.Surgical treatment aims were anatomic repositioning and rigid fixation of the fragments, occlusal stability, rapidly return to function, maintenance of vertical ramus dimension, no airway compromise, and reduced long-term temporomandibular joint dysfunction. Considering the high rate of occurrence of condylar fracture and the importance of the condylar as a growth center of the mandible, extraoral approaches for the open reduction of condylar fractures are considered effective and can be used widely.Short access route, easy reduction, short operating time, and stable postoperative occlusion are the advantages of the retromandibular transparotid approach. Also, there was no permanent damage from facial nerve injury, salivary leakage, or preauricular hypoesthesia. Therefore, the retromandibular transparotid approach is considered a safe and effective method for patients with a condylar neck or condylar base fracture classified according to the Strasbourg Osteosynthesis Research Group's classification, who require surgical treatment with an extraoral approach.

  19. Factors associated with antenatal depression in pregnant Korean females: the effect of bipolarity on depressive symptoms

    Directory of Open Access Journals (Sweden)

    Park CM

    2014-06-01

    Full Text Available Chul Min Park,1 Hye-Jin Seo,2 Young-Eun Jung,3 Moon-Doo Kim,3 Seong-Chul Hong,4 Won-Myong Bahk,5 Bo-Hyun Yoon,6 Min Hee Hur,7 Jae Min Song31Department of Obstetrics and Gynecology, School of Medicine, Jeju National University, Jeju, 2Department of Psychiatry, Yeonkang Hospital, Jeju, 3Department of Psychiatry, 4Department of Preventive Medicine, School of Medicine, Jeju National University, Jeju, 5Department of Psychiatry, Yeouido St Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, 6Department of Psychiatry, Naju National Hospital, Naju, 7School of Medicine, Jeju National University, Jeju, KoreaBackground: This cross-sectional study sought to identify factors associated with antenatal depression in pregnant Korean females, including sociodemographic parameters, social support, social conflict, and bipolarity.Methods: Eighty-four pregnant women were recruited to complete questionnaires on sociodemographic factors, obstetric history, depressive symptoms, and bipolarity. Depressive symptoms were assessed using the Korean version of the Edinburgh Postnatal Depression Scale. Bipolarity was assessed using the Korean version of the Mood Disorder Questionnaire.Results: Nineteen participants (22.6% had positive Mood Disorder Questionnaire scores, suggesting the presence of bipolarity, and were significantly more likely to score high on the Edinburgh Postnatal Depression Scale. Antenatal depression was associated with bad marital communication and marital dissatisfaction.Conclusion: These results suggest that spousal interactions play a significant role in antenatal depression, and pregnant women with bipolarity may be more depressed than those without bipolarity.Keywords: antenatal depression, bipolarity, pregnancy, Korea

  20. Reversible vasectomy--reports from Korea and India.

    Science.gov (United States)

    1971-08-01

    The vasectomy technique of Dr. Hee Yong Lee, deliberately designed to allow for the possibility of reversibility, is described. This Korean method involves reversible vas occlusion obtained through insertion of non-reactive and non-absorbable suture materials into the vas. This vas plug is 1 to 2 cm. in length and has two 8 cm. strings of filiform silk attached to one end. The filiform threads enhance easy insertion without cutting the vas, prevent migration of the plug, and avoid the need for an incision in the vas for removal of the plug. A 3-4 cm. length of vas is exposed under local anesthesia and the plug is inserted into the vas by means of a straight needle threaded with the filiform threads. The filiform threads are then loosely tied around the vas. The plug is removed by cutting and then pulling the filiform threads with a pair of mosquito forceps. Twenty of 350 men who had the plugs inserted were subjected to reversibility about 6 months later. Viable sperm specimens were obtained a month after removal of the plug in 17 of the 20. In 2 of the 3 other cases, the vas was accidently cut during removal. In the third case, fibrosis was noted around the plug. Nearly all vasectomies can be reversed if care is taken with the original procedure. Dr. V. N. Shrikhande's vasectomy technique in India is also described. Less than a one cm. segment of the vas is removed. The cut ends are crushed and ligated with fine non-absorbable sutures. The lower cut end is buried within the connective tissue sheath by non-absorbable sutures. This Indian doctor reports that a reversibility rate of over 90% is possible. Three pitfalls of vasectomy reported are: a long segment of the vas unnecessarily removed, excessive close stripping of the vas, and the vas divided too low down near the head of the epididymis.

  1. Changes in cerebral blood flow after cognitive behavior therapy in patients with panic disorder: a SPECT study

    Directory of Open Access Journals (Sweden)

    Seo HJ

    2014-04-01

    Full Text Available Ho-Jun Seo,1 Young Hee Choi,2 Yong-An Chung,3 Wangku Rho,1 Jeong-Ho Chae11Department of Psychiatry, College of Medicine, The Catholic University of Korea, Seoul, South Korea; 2Metta Institute of Cognitive Behavior Therapy, Seoul, South Korea; 3Department of Radiology, Nuclear Medicine, College of Medicine, The Catholic University of Korea, Seoul, South KoreaAim: Inconsistent results continue to be reported in studies that examine the neural correlates of cognitive behavioral therapy (CBT in patients with panic disorder. We examined the changes in regional cerebral blood flow (rCBF associated with the alleviation of anxiety by CBT in panic patients.Methods: The change in rCBF and clinical symptoms before and after CBT were assessed using single photon emission computed tomography and various clinical measures were analyzed.Results: Fourteen subjects who completed CBT showed significant improvements in symptoms on clinical measures, including the Panic and Agoraphobic Scale and the Anxiety Sensitivity Index-Revised. After CBT, increased rCBF was detected in the left postcentral gyrus (BA 43, left precentral gyrus (BA 4, and left inferior frontal gyrus (BA 9 and BA 47, whereas decreased rCBF was detected in the left pons. Correlation analysis of the association between the changes in rCBF and changes in each clinical measure did not show significant results.Conclusion: We found changes in the rCBF associated with the successful completion of CBT. The present findings may help clarify the effects of CBT on changes in brain activity in panic disorder.Keyword: single photon emission computed tomography (SPECT, anxiety, neural correlate, brain activity

  2. Enhanced bioavailability of sirolimus via preparation of solid dispersion nanoparticles using a supercritical antisolvent process

    Directory of Open Access Journals (Sweden)

    Kim MS

    2011-11-01

    Full Text Available Min-Soo Kim1, Jeong-Soo Kim1, Hee Jun Park1, Won Kyung Cho1,3, Kwang-Ho Cha1,3, Sung-Joo Hwang2,31College of Pharmacy, Chungnam National University, Daejeon, Republic of Korea, 2College of Pharmacy, 3Yonsei Institute of Pharmaceutical Sciences, Yonsei University, Incheon, Republic of KoreaBackground: The aim of this study was to improve the physicochemical properties and bioavailability of poorly water-soluble sirolimus via preparation of a solid dispersion of nanoparticles using a supercritical antisolvent (SAS process.Methods: First, excipients for enhancing the stability and solubility of sirolimus were screened. Second, using the SAS process, solid dispersions of sirolimus-polyvinylpyrrolidone (PVP K30 nanoparticles were prepared with or without surfactants such as sodium lauryl sulfate (SLS, tocopheryl propylene glycol succinate, Sucroester 15, Gelucire 50/13, and Myrj 52. A mean particle size of approximately 250 nm was obtained for PVP K30-sirolimus nanoparticles. Solid state characterization, kinetic solubility, powder dissolution, stability, and pharmacokinetics were analyzed in rats.Results: X-ray diffraction, differential scanning calorimetry, and high-pressure liquid chromatography indicated that sirolimus existed in an anhydrous amorphous form within a solid dispersion of nanoparticles and that no degradation occurred after SAS processing. The improved supersaturation and dissolution of sirolimus as a solid dispersion of nanoparticles appeared to be well correlated with enhanced bioavailability of oral sirolimus in rats. With oral administration of a solid dispersion of PVP K30-SLS-sirolimus nanoparticles, the peak concentration and AUC0→12h of sirolimus were increased by approximately 18.3-fold and 15.2-fold, respectively.Conclusion: The results of this study suggest that preparation of PVP K30-sirolimus-surfactant nanoparticles using the SAS process may be a promising approach for improving the bioavailability of sirolimus

  3. Evaluation of Nickel Allergic Reactions to the Essure Micro Insert: Theoretical Risk or Daily Practice?

    Science.gov (United States)

    Siemons, Sara; Vleugels, Michel; van Eijndhoven, Hugo

    2017-01-01

    To evaluate whether de novo development of nickel sensitization is related to placement of the Essure device, and to evaluate whether the grade of reaction to nickel increased after device placement in patients with a confirmed nickel allergy. Prospective cohort study (Canadian Task Force classification II-2). Two nonacademic training hospitals in The Netherlands. Healthy women of childbearing age desiring permanent sterilization. At least 72 hours before Essure sterilization, each patient received 2 patches, 1 patch with a nickel solution in 5% petrolatum and 1 control patch. In addition, the patient was asked to complete a questionnaire on allergy-related symptoms. The patch test was scored according to the criteria for contact dermatitis of Devos and Van Der Valk. At 3 months after Essure sterilization, the patch test and the questionnaire were repeated. All 169 patients underwent Essure sterilization and completed the patch test cycle. There were no statistically significant changes in patch test results and allergy-related symptoms after sterilization. Before sterilization, 29% of the patients had a positive patch test and 1.8% also showed a positive reaction to the control patch. Only 20.7% of the patients had a history of allergic reactions to nickel. After sterilization, 29% had a positive patch test and 0.6% also showed a positive reaction to the control patch. Among the patients with a positive patch test before sterilization, the grade of reaction did not increase after sterilization. Moreover, these patients did not exhibit any increase in allergy-related symptoms. Among 4 patients with a previous negative patch test, 2 developed a grade 1 reaction and 2 developed a grade 2 reaction after sterilization. Two of these 4 patients had a history of allergic reactions to nickel before sterilization despite a negative patch test. After sterilization, these 4 patients exhibited no increase in allergy-related symptoms. There were no statistically significant

  4. Technical and radiological image quality comparison of different liquid crystal displays for radiology

    Directory of Open Access Journals (Sweden)

    Dams FE

    2014-10-01

    Full Text Available Francina EM Dams,2 KY Esther Leung,1 Pieter HM van der Valk,2 Marc CJM Kock,2 Jeroen Bosman,1 Sjoerd P Niehof1 1Medical Physics and Technology, 2Department of Radiology, Albert Schweitzer Hospital, Dordrecht, The Netherlands Background: To inform cost-effective decisions in purchasing new medical liquid crystal displays, we compared the image quality in displays made by three manufacturers. Methods: We recruited 19 radiologists and residents to compare the image quality of four liquid crystal displays, including 3-megapixel Barco®, Eizo®, and NEC® displays and a 6-megapixel Barco display. The evaluators were blinded to the manufacturers' names. Technical assessments were based on acceptance criteria and test patterns proposed by the American Association of Physicists in Medicine. Radiological assessments were performed on images from the American Association of Physicists in Medicine Task Group 18. They included X-ray images of the thorax, knee, and breast, a computed tomographic image of the thorax, and a magnetic resonance image of the brain. Image quality was scored on an analog scale (range 0–10. Statistical analysis was performed with repeated-measures analysis of variance. Results: The Barco 3-megapixel display passed all acceptance criteria. The Eizo and NEC displays passed the acceptance criteria, except for the darkest pixel value in the grayscale display function. The Barco 6-megapixel display failed criteria for the maximum luminance response and the veiling glare. Mean radiological assessment scores were 7.8±1.1 (Barco 3-megapixel, 7.8±1.2 (Eizo, 8.1±1.0 (NEC, and 8.1±1.0 (Barco 6-megapixel. No significant differences were found between displays. Conclusion: According to the tested criteria, all the displays had comparable image quality; however, there was a three-fold difference in price between the most and least expensive displays. Keywords: data display, humans, radiographic image enhancement, user-computer interface

  5. Cattle grazing and its long-term effects on sedge meadows

    Science.gov (United States)

    Middleton, Beth

    2004-01-01

    Most people think that wetlands are temporary, that they fill in by natural processes, and eventually become dry land. Some of these outdated ideas have come from the way that this subject has been covered in introductory textbooks in schools (Gibson, 1996). From these texts, we learned incorrectly that over time a lake fills with sediment or organic matter to become a wetland, which dries out to support shrubs and trees, and eventually it is no longer a wetland (Middleton, 1999; Middleton and others, 2004). These old ideas of how vegetation changes (succession) are no longer accepted. Wetland succession should be thought of as a cycle, with natural disturbance driving the changes, depending on the needs of the species. Succession is not something that changes a wetland into something that is not a wetland (Egler, 1978; van der Valk, 1981; Middleton and others, 1991; Klinger, 1996; Middleton, 1999).As an example of how disturbance changes wetlands, I have studied sedge meadows that have become invaded by shrubs after cattle (Bos sp.) have grazed them, in the Lodi Marsh State Natural Area, Wisconsin. Cattle disturbances allowed shrubs to invade sedge meadows, but the cattle also grazed on the shrubs, which kept them small. After the cows were removed, the plant species changed in the sedge meadow from the original sedges (fig. 1), to sedges mixed with growing small shrubs, and eventually to tall shrubs with very small amounts of sedge, called “shrub carr” (Middleton, 2002a). Even though there has been a succession of plant types, the meadows, which began as wetlands, have remained wetlands. The settlers originally found the sedge meadows to be open “sedge” lands and not shrubby. The settlers cut the sedges by hand to feed the cattle. Whitetailed deer (Odocoileus virginianus), though probably not bison (Bison bison), grazed these sedge meadows (Middleton 2002a).Subsequent studies have explored methods to control invasive shrubs to restore the biodiversity of

  6. Quality of life and adherence to inhaled corticosteroids and tiotropium in COPD are related

    Directory of Open Access Journals (Sweden)

    Koehorst-ter Huurne K

    2016-07-01

    Full Text Available Kirsten Koehorst-ter Huurne,1 Sharina Kort,1 Job van der Palen,1,3 Wendy JC van Beurden,1 Kris LL Movig,2 Paul van der Valk,1 Marjolein Brusse-Keizer1 1Department of Pulmonary Medicine, 2Department of Clinical Pharmacy, Medisch Spectrum Twente, 3Department of Research Methodology, Measurement, and Data Analysis, University of Twente, Enschede, the Netherlands Background: Poor adherence to inhaled medications in COPD patients seems to be associated with an increased risk of death and hospitalization. Knowing the determinants of nonadherence to inhaled medications is important for creating interventions to improve adherence. Objectives: To identify disease-specific and health-related quality of life (HRQoL factors, associated with adherence to inhaled corticosteroids (ICS and tiotropium in COPD patients. Methods: Adherence of 795 patients was recorded over 3 years and was deemed optimal at >75%–≤125%, suboptimal at ≥50%–<75%, and poor at <50% (underuse or >125% (overuse. Health-related quality of life was measured with the Clinical COPD Questionnaire and the EuroQol-5D questionnaire. Results: Patients with a higher forced expiratory volume in 1 second (FEV1/vital capacity (VC (odds ratio [OR] =1.03 and ≥1 hospitalizations in the year prior to inclusion in this study (OR =2.67 had an increased risk of suboptimal adherence to ICS instead of optimal adherence. An increased risk of underuse was predicted by a higher FEV1/VC (OR =1.05. Predictors for the risk of overuse were a lower FEV1 (OR =0.49, higher scores on Clinical COPD Questionnaire-question 3 (anxiety for dyspnea (OR =1.26, and current smoking (OR =1.73. Regarding tiotropium, predictors for suboptimal use were a higher FEV1/VC (OR =1.03 and the inability to perform usual activities as asked by the EuroQol-5D questionnaire (OR =3.09. A higher FEV1/VC also was a predictor for the risk of underuse compared to optimal adherence (OR =1.03. The risk of overuse increased again with higher

  7. Delivery of dexamethasone from bioactive nanofiber matrices stimulates odontogenesis of human dental pulp cells through integrin/BMP/mTOR signaling pathways

    Directory of Open Access Journals (Sweden)

    Lim HC

    2016-06-01

    Full Text Available Hyun-Chang Lim,1,* Ok Hyung Nam,2,* Mi-joo Kim,3 Ahmed El-Fiqi,4,5 Hyung-Mun Yun,3 Yoo-Mi Lee,3 Guang-Zhen Jin,4,5 Hae-Hyoung Lee,5,6 Hae-Won Kim,4–6 Eun-Cheol Kim3 1Department of Periodontology, 2Department of Pediatric Dentistry, 3Department of Oral and Maxillofacial Pathology, Research Center for Tooth and Periodontal Regeneration (MRC, School of Dentistry, Kyung Hee University, Seoul, 4Department of Nanobiomedical Science, BK21 PLUS NBM Global Research Center for Regenerative Medicine, 5Institute of Tissue Regeneration Engineering, 6Department of Biomaterials Science, College of Dentistry, Dankook University, Cheonan, Republic of Korea *These authors contributed equally to this work as first authors Abstract: Therapeutically relevant design of scaffolds is of special importance in the repair and regeneration of tissues including dentin and pulp. Here we exploit nanofiber matrices that incorporate bioactive glass nanoparticles (BGNs and deliver the odontogenic drug dexamethasone (DEX to stimulate the odontogenic differentiation of human dental pulp cells (HDPCs. DEX molecules were first loaded onto the BGN, and then the DEX-BGN complex was incorporated within the biopolymer nanofiber matrix through electrospinning. The release of DEX continued over a month, showing a slow releasing profile. HDPCs cultured on the DEX-releasing BGN matrices were viable, proliferating well up to 14 days. The odontogenic differentiation, as assessed by alkaline phosphatase activity, mRNA expression of genes, and mineralization, was significantly stimulated on the matrices incorporating BGN and further on those releasing DEX. The DEX-releasing BGN matrices highly upregulated the expression of the integrin subsets α1, α5, and β3 as well as integrin downstream signaling molecules, including focal adhesion kinase (FAK, Paxillin, and RhoA, and activated bone morphogenetic protein mRNA and phosphorylation of Smad1/5/8. Furthermore, the DEX-releasing BGN

  8. Anticancer activity of streptochlorin, a novel antineoplastic agent, in cholangiocarcinoma

    Directory of Open Access Journals (Sweden)

    Kwak TW

    2015-04-01

    Full Text Available Tae Won Kwak,1,* Hee Jae Shin,2,* Young-Il Jeong,1 Myoung-Eun Han,3 Sae-Ock Oh,3 Hyun-Jung Kim,4 Do Hyung Kim,5 Dae Hwan Kang1 1Biomedical Research Institute, Pusan National University Hospital, Busan, 2Marine Natural Products Chemistry Laboratory, Korea Institute of Ocean Science and Technology, Ansan, 3Department of Anatomy, School of Medicine, Pusan National University, Gyeongnam, 4Genewel Co Ltd. Gyeonggi-do, 5School of Medicine, Pusan National University, Yangsan, Gyeongnam, Republic of Korea *These authors contributed equally to this work Background: The aim of this study is to investigate the anticancer activity of streptochlorin, a novel antineoplastic agent, in cholangiocarcinoma. Methods: The anticancer activity of streptochlorin was evaluated in vitro in various cholangiocarcinoma cell lines for apoptosis, proliferation, invasiveness, and expression of various protein levels. A liver metastasis model was prepared by splenic injection of HuCC-T1 cholangiocarcinoma cells using a BALB/c nude mouse model to study the systemic antimetastatic efficacy of streptochlorin 5 mg/kg at 8 weeks. The antitumor efficacy of subcutaneously injected streptochlorin was also assessed using a solid tumor xenograft model of SNU478 cells for 22 days in the BALB/c nude mouse. Results: Streptochlorin inhibited growth and secretion of vascular endothelial growth factor by cholangiocarcinoma cells in a dose-dependent manner and induced apoptosis in vitro. In addition, streptochlorin effectively inhibited invasion and migration of cholangiocarcinoma cells. Secretion of vascular endothelial growth factor and activity of matrix metalloproteinase-9 in cholangiocarcinoma cells were also suppressed by treatment with streptochlorin. Streptochlorin effectively regulated metastasis of HuCC-T1 cells in a mouse model of liver metastasis. In a tumor xenograft study using SNU478 cells, streptochlorin significantly inhibited tumor growth without changes in body weight

  9. Development of paclitaxel-loaded liposomal nanocarrier stabilized by triglyceride incorporation

    Directory of Open Access Journals (Sweden)

    Hong SS

    2016-09-01

    Full Text Available Soon-Seok Hong,1 Ju Yeon Choi,2 Jong Oh Kim,2 Mi-Kyung Lee,3 So Hee Kim,4 Soo-Jeong Lim1 1Department of Bioscience and Bioengineering, Sejong University, Seoul, 2College of Pharmacy, Yeungnam University, Gyeongsan, 3College of Pharmacy, Woosuk University, Wanju-gun, Jeollabuk-do, 4College of Pharmacy and Research Institute of Pharmaceutical Science and Technology, Ajou University, Suwon, Republic of Korea Abstract: Studies have highlighted the challenge of developing injectable liposomes as a paclitaxel (PTX carrier, a challenge attributable to the limitations in liposomal stability caused by PTX loading. Poor stability of PTX-loaded liposomes is caused by PTX-triggered aggregation or fusion of liposomal membranes and is exacerbated in the presence of PEGylated lipid. In the present study, the effect of triglyceride incorporation on the stability of PTX-loaded/PEGylated liposomes was explored. Incorporation of a medium chain triglyceride Captex 300 into saturated phosphatidylcholine (PC-based liposomes (1,2-dimyristoyl-sn-glycero-3-phosphocholine [DMPC]:cholesterol [CHOL]:N-(Carbonyl-methoxypolyethyleneglycol 2000-1, 2-distearoyl-sn-glycero-3-phospho-ethanolamine [PE-PEG], produced a fine, homogeneous, and membrane-filterable PTX-loaded liposomes fulfilling the requirement of an injectable lipid formulation. Triglyceride incorporation also greatly inhibited the time-dependent leakage of PTX from saturated PC-based liposomes, which appears to be mediated by the inhibition of liposome fusion. In contrast, triglyceride incorporation induced the destabilization and PTX leakage of unsaturated PC-based liposomes, indicating the opposite effect of triglyceride depending on the fluidity status of PC constituting the liposomal membrane. PTX release profile and the in vitro and in vivo anticancer efficacy of triglyceride-incorporated DMPC:CHOL:PE-PEG liposomes were similar to Taxol® while the toxicity of liposomal PTX was significantly lower than that of

  10. Lower serum brain-derived neurotrophic factor levels are associated with failure to achieve remission in patients with major depression after escitalopram treatment

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    Lee BH

    2014-07-01

    Full Text Available Bun-Hee Lee,1 Young-Min Park,2 Tae Hyun Um,3 Sollip Kim3 1Department of Psychiatry, Gangnam Eulji Hospital, Eulji University, Seoul, 2Department of Psychiatry, 3Department of Laboratory Medicine, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, South Korea Background: Remission, the primary goal of treatment for major depressive disorder (MDD, is the absence of significant signs or symptoms and the return to a state of normal functioning. A recent study found that the level of brain-derived neurotrophic factor (BDNF increased after antidepressant treatment in remitted patients. This study evaluated serum BDNF levels in MDD patients with chronic maintenance treatment, and compared these between remission and nonremission groups.Materials and methods: Serum BDNF levels were measured in 34 MDD patients and 35 healthy controls. The severity of depression was measured using the Hamilton Depression Rating Scale (Ham-D. The MDD patients were divided into remission and nonremission groups according to a cutoff total Ham-D score of either ≤7 or ≤6.Results: Serum BDNF levels differed significantly between the remission, nonremission, and healthy control groups (P<0.05. The Bonferroni post hoc test confirmed that serum BDNF levels were significantly lower in the nonremission group than in the healthy-control group (P<0.05, but did not differ significantly between the remission and healthy-control groups.Limitations: This study included a small sample, and measured serum BDNF levels in the MDD patients at only one point during the maintenance treatment.Conclusion: This study found that serum BDNF levels during maintenance treatment were lower in MDD patients with failure to achieve remission than in controls, while the remitted subjects had normalized serum BDNF levels. A lower level of serum BDNF during maintenance treatment is associated with failure to achieve remission in patients with major depression. Moreover, serum BDNF levels

  11. Design of Installing Check Dam Using RAMMS Model in Seorak National Park of South Korea

    Science.gov (United States)

    Jun, K.; Tak, W.; JUN, B. H.; Lee, H. J.; KIM, S. D.

    2016-12-01

    Design of Installing Check Dam Using RAMMS Model in Seorak National Park of South Korea Kye-Won Jun*, Won-Jun Tak*, Byong-Hee Jun**, Ho-Jin Lee***, Soung-Doug Kim* *Graduate School of Disaster Prevention, Kangwon National University, 346 Joogang-ro, Samcheok-si, Gangwon-do, Korea **School of Fire and Disaster Protection, Kangwon National University, 346 Joogang-ro, Samcheok-si, Gangwon-do, Korea ***School of Civil Engineering, Chungbuk National University, 1 Chungdae-ro, Seowon-gu, Cheongju, Korea Abstract As more than 64% of the land in South Korea is mountainous area, so many regions in South Korea are exposed to the danger of landslide and debris flow. So it is important to understand the behavior of debris flow in mountainous terrains, the various methods and models are being presented and developed based on the mathematical concept. The purpose of this study is to investigate the regions that experienced the debris flow due to typhoon called Ewiniar and to perform numerical modeling to design and layout of the Check dam for reducing the damage by the debris flow. For the performance of numerical modeling, on-site measurement of the research area was conducted including: topographic investigation, research on bridges in the downstream, and precision LiDAR 3D scanning for composed basic data of numerical modeling. The numerical simulation of this study was performed using RAMMS (Rapid Mass Movements Simulation) model for the analysis of the debris flow. This model applied to the conditions of the Check dam which was installed in the upstream, midstream, and downstream. Considering the reduction effect of debris flow, the expansion of debris flow, and the influence on the bridges in the downstream, proper location of the Check dam was designated. The result of present numerical model showed that when the Check dam was installed in the downstream section, 50 m above the bridge, the reduction effect of the debris flow was higher compared to when the Check dam were

  12. Toll-like receptor 3-induced immune response by poly(D,L-lactide-co-glycolide nanoparticles for dendritic cell-based cancer immunotherapy

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    Han HD

    2016-11-01

    Full Text Available Hee Dong Han,1,* Yeongseon Byeon,1,* Tae Heung Kang,1 In Duk Jung,1 Jeong-Won Lee,2 Byung Cheol Shin,3 Young Joo Lee,4 Anil K Sood,5–7 Yeong-Min Park1 1Department of Immunology, School of Medicine, Konkuk University, Chungwondaero, Chungju-Si, Chungcheongbuk-Do, 2Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, 3Bio/Drug Discovery Division, Korea Research Institute of Chemical Technology, Yuseong-gu, Daejeon, 4Department of Bioscience and Biotechnology, Sejong University, Kwang-Jin-Gu, Seoul, South Korea; 5Department of Gynecologic Oncology and Reproductive Medicine, 6Department of Cancer Biology, 7Center for RNA Interference and Non-coding RNA, The University of Texas MD Anderson Cancer Center, TX, USA *These authors contributed equally to this work Abstract: Dendritic cells (DCs are potent professional antigen-presenting cells that are capable of initiating a primary immune response and activating T cells, and they play a pivotal role in the immune responses of the host to cancer. Prior to antigen presentation, efficient antigen and adjuvant uptake by DCs is necessary to induce their maturation and cytokine generation. Nanoparticles (NPs are capable of intracellular delivery of both antigen and adjuvant to DCs. Here, we developed an advanced poly(D,L-lactide-co-glycolide (PLGA-NP encapsulating both ovalbumin (OVA as a model antigen and polyinosinic-polycytidylic acid sodium salt (Toll-like receptor 3 ligand as an adjuvant to increase intracellular delivery and promote DC maturation. The PLGA-NPs were taken up by DCs, and their uptake greatly facilitated major histocompatibility class I antigen presentation in vitro. Moreover, vaccination with PLGA-NP-treated DCs led to the generation of ovalbumin-specific CD8+ T cells, and the resulting antitumor efficacy was significantly increased in EG.7 and TC-1 tumor-bearing mice compared to control mice (P<0.01. Taken together, these

  13. Effect of a health coaching self-management program for older adults with multimorbidity in nursing homes

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    Park YH

    2014-07-01

    Full Text Available Yeon-Hwan Park,1,2 HeeKyung Chang31College of Nursing, 2The Research Institute of Nursing Science, Seoul National University, Seoul, South Korea; 3Seoul Women’s College of Nursing, Seoul, South KoreaBackground and aims: Although a growing number of older people are suffering from multimorbidity, most of the health problems related to multimorbidity can be improved by self-management. The aim of this study was to examine the effectiveness of a health coaching self-management program for older adults with multimorbidity in nursing homes. Methods: Older adults with multimorbidity from one nursing home in Korea were randomly allocated to either an intervention group (n=22 or conventional group (n=21. Participants in the intervention group met face to face with the researchers twice a week for 8 weeks, during which time the researchers engaged them in goal setting and goal performance using the strategies in the health coaching self-management program. Regular care was provided to the other participants in the conventional group. Results: Participants in the intervention group had significantly better outcomes in exercise behaviors (P=0.015, cognitive symptom management (P=0.004, mental stress management/relaxation (P=0.023, self-rated health (P=0.002, reduced illness intrusiveness (P<0.001, depression (P<0.001, and social/role activities limitations (P<0.001. In addition, there was a significant time-by-group interaction in self-efficacy (P=0.036. According to the goal attainment scales, their individual goals of oral health and stress reduction were achieved.Conclusion: The health coaching self-management program was successfully implemented in older adults with multimorbidity in a nursing home. Further research is needed to develop and evaluate the long-term effects of an intervention to enhance adherence to self-management and quality of life for older adults with multimorbidity.Keywords: chronic diseases, nursing intervention, older adults

  14. Postoperative pain and patient-controlled epidural analgesia-related adverse effects in young and elderly patients: a retrospective analysis of 2,435 patients

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    Koh JC

    2017-04-01

    Full Text Available Jae Chul Koh, Young Song, So Yeon Kim, Sooyeun Park, Seo Hee Ko, Dong Woo Han Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, South Korea Abstract: In this retrospective study, data of 2,435 patients who received fentanyl and ropivacaine-based patient-controlled epidural analgesia (PCEA for pain relief after elective surgery under general or spinal anesthesia were reviewed. Differences in postoperative pain, incidence of patient-controlled analgesia (PCA-related adverse effects, and risk factors for the need for rescue analgesics for 48 hours postsurgery in young (age 20–39 years and elderly (age ≥70 years patients were evaluated. Although there were no significant differences in postoperative pain intensity between the two groups until 6 hours postsurgery, younger patients experienced greater postoperative pain intensity compared with older patients 6–48 hours postsurgery. While younger patients exhibited greater incidence of numbness, motor weakness, and discontinuation of PCA postsurgery, elderly patients exhibited greater incidence of hypotension, nausea/vomiting, rescue analgesia, and antiemetic administration. Upon multivariate analysis, low fentanyl dosage and history of smoking were found to be associated with an increased need for rescue analgesia among younger patients, while physical status classification III/IV and thoracic surgery were associated with a decreased need for rescue analgesia among the elderly. Discontinuation of PCA was more frequent among younger patients than the elderly (18.5% vs 13.5%, P=0.001. Reasons for discontinuation of PCA among young and elderly patients, respectively, were nausea and vomiting (6.8% vs 26.6%, numbness or motor weakness (67.8% vs 11.5%, urinary retention (7.4% vs 8.7%, dizziness (2.2% vs 5.2%, and hypotension (3.1% vs 20.3%. In conclusion, PCEA was more frequently associated with numbness, motor

  15. Psychometric properties of the Korean version of the Pulmonary Rehabilitation Adapted Index of Self-Efficacy (PRAISE for individuals with COPD

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    Song HY

    2017-08-01

    Full Text Available Hee-Young Song,1 Kyoung A Nam2 1Department of Nursing, Wonju College of Medicine, Yonsei University, Wonju, South Korea; 2Division of Nursing, Hallym University, Chuncheon, South Korea Purpose: Self-efficacy is related to the emotional functioning and coping skills of an individual and is thought to be a predictor of health behaviors, which are particularly important for pulmonary rehabilitation (PR. To our knowledge, no measure of self-efficacy has been validated to explore behavior changes in the context of PR for patients with COPD in Korea. This study aimed to evaluate the psychometric properties of the Korean version of the Pulmonary Rehabilitation Adapted Index of Self-Efficacy (PRAISE.Patients and methods: The original scale, developed and validated by Vincent et al was translated into Korean through a process involving forward and back translation of the original scale, and transcultural adaptation was performed following the structured procedure. Content validity was assessed by a panel of 6 expert judges. In a convenience sample of 118 patients with COPD, exploratory factor analysis using principal axis factoring, followed by oblique rotation was conducted to identify construct validity, and the concurrent validity was evaluated by testing correlations between the PRAISE and 6-minute walking distance test and the PRAISE and Saint George Respiratory Questionnaire results. Internal consistency was examined by calculating Cronbach’s alpha coefficients.Results: Exploratory factor analysis confirmed the 2-dimensional structure of the scale constructed from the original 15-item scale. The final scale was composed of 14 items that cumulatively explained 60.3% of the total variance. The 2 factors in the scale were named “general self-efficacy” and “exercise self-efficacy.” Significant correlations between the PRAISE, and 6-minute walking distance test and Saint George Respiratory Questionnaire showed the concurrent validity of the

  16. Study on Comprehensive Experiments Teaching of Microbiology Using Anaerobic Decomposition Experiment%通过厌氧消化实验探讨《微生物学》综合性实验教学

    Institute of Scientific and Technical Information of China (English)

    代先祝; 张磊

    2012-01-01

    通过对厌氧消化实验教学过程的改革研究,以提高学生实践能力和创新精神为目的,探讨了微生物学综合性实验教学的新方法.%[ Objective] To analyze the research status of articles on intestinal flora from 1900 to 2010 using a bibliometric approach. [ Method] Literature on intestinal flora from the Web of Sciences Science Citation Index Expanded database during 1900 -2010 was searched. The search results were analyzed with regard to the number of articles and the frequency of citations by country, institution and author, journal of publication, and subjects covered by the article. [ Result] In total, 8838 articles related to intestinal flora were published and distributed in more than 490 kinds of journals from 1900 to 2010, covering Microbiology ( 1509 articles, 17.07% ) , Gastroenterology & Hepatology (935 articles, 10.58% ) , and Pharmacology & Pharmacy (894 articles, 10. 12% ) . The three journals with the highest impact factors were Gastroenterology (12.899), Cut (9.537) and American Jornal of chinical Nutrition (6.307); The top 3 countries in terms of articles published were USA (2005 articles, 22.69% ), Japan (1031 articles, 11. 67% ) and UK (688 articles, 7. 78% ), China (285 articles, 3. 22% ) ranked the 10th in the world. Kim DH (Korea, 118 articles) , Nord CE (Sweden, 102 articles) and Gibson GR (UK, 89 articles) published the most articles. KAROLINSKA INST (Sweden, 185 articles), INRA( French National Institute for agricultural research, 168 articles) and KYUNG HEE UNIV (Korea ,118 articles) accounted for the top 3 total number of the papers, and the top 3 institutions in the largest number of papers in China were Chinese Academy of Sciences (45 articles) , Shanghai Jiaotong University (20 articles) and Zhejiang University(20 articles). [Conclusion] Developed countries played a leading role in research on intestinal flora. China also had made significant contributions to the progress of the related research. But

  17. A radiographic study of solitary bone cysts

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    Kim, Kyung Rak; Hwang, Eui Hwan; Lee, Sang Rae [Dept. of Oral and Maxillofacial Radiology, Division of Dentistry, Kyung Hee University, Seoul (Korea, Republic of)

    1994-02-15

    The aim of this study was to evaluate the clinical, radiographic and histopathologic features of 23 cases of solitary bone cyst by means of the analysis of radiographs and biopsy specimens in 23 persons visited the Department of Oral and Maxillofacial Radiology, School of Dentistry, Kyung Hee University and Chunbuk National University. The obtained results were as follows; 1. The incidence of solitary bone cyst was almost equal in males (52.2%) and in females(42.8%) and the prevalent age of the solitary bone cyst were the second decade (47.8%) and the third decade (21.7%). 2. In the signs and symptoms of solitary bone cyst, pain or tenderness revealed in 17.4%, swelling revealed in 13.0%, pain and swelling revealed in 21.7%, paresthesia revealed in 4.4% and 43.5% were a symptom and the tooth vitality involved in the solitary bone cyst, 76.5% were posterior and 23.5% were either positive or negative. 3. In the location of the solitary bone cyst, 47.8% present posterior region, 21.7% present anterior region, 21.6% present anterior and posterior region, 4.4% present condylar process area. 4. In the hyperostotic border of the solitary bone cyst, 47.8% were seen entirely, 21.8% were seen partially, and 30.4% were not seen. 5. In the change of tooth, 59.1% were loss of the alveolar lamina dura, 13.6% were root resorption 4.55% were tooth displacement, 4.55% were root resorption and tooth displacement. 6. In the change of cortical bone of the solitary bone cyst, 39.1% were intact and 60.9% were thinning and expansion of cortical bone. 7. In the histopathologic findings of 9 cases, 33.3% were thin connective tissue wall, 11.1% were thickened myxo-fibromatous wall, 55.6% were thickened myxofibromatous wall with dysplastic bone formation.

  18. Optimal medical therapy for secondary prevention after an acute coronary syndrome: 18-month follow-up results at a tertiary teaching hospital in South Korea

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    Byeon HJ

    2016-02-01

    Full Text Available Hee Ja Byeon,1,* Young-Mo Yang,2,* Eun Joo Choi21Department of Pharmacy, Chosun University Hospital, 2Department of Pharmacy, College of Pharmacy, Chosun University, Gwangju, South Korea*These authors contributed equally to this workBackground: Acute coronary syndrome (ACS is a fatal cardiovascular disease caused by atherosclerotic plaque erosion or rupture and formation of coronary thrombus. The latest guidelines for ACS recommend the combined drug regimen, comprising aspirin, P2Y12 inhibitor, angiotensin-converting enzyme inhibitor or angiotensin II receptor blocker, β-blocker, and statin, at discharge after ACS treatment to reduce recurrent ischemic cardiovascular events. This study aimed to examine prescription patterns of secondary prevention drugs in Korean patients with ACS after hospital discharge, to access the appropriateness of secondary prevention drug therapy for ACS, and to evaluate whether to persistently use discharge medications for 18 months.Methods: This study was retrospectively conducted with the patients who were discharged from the tertiary hospital, located in South Korea, after ACS treatment between September 2009 and August 2013. Data were collected through electronic medical record.Results: Among 3,676 patients during the study period, 494 were selected based on inclusion and exclusion criteria. The regimen of aspirin + clopidogrel + β-blocker + angiotensin-converting enzyme inhibitor/angiotensin II receptor blocker + statin was prescribed to 374 (75.71% patients with ACS at discharge. Specifically, this regimen was used in 177 (69.69% unstable angina patients, 44 (70.97% non-ST-segment elevation myocardial infarction patients, and 153 (85.96% ST-segment elevation myocardial infarction patients. Compared with the number of ACS patients with all five guideline-recommended drugs at discharge, the number of ACS patients using them 12 (n=169, 34.21% and 18 (n=105, 21.26% months after discharge tended to be gradually

  19. Association of incidental emphysema with annual lung function decline and future development of airflow limitation

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    Koo HK

    2016-01-01

    Full Text Available Hyeon-Kyoung Koo,1 Kwang Nam Jin,2 Deog Kyeom Kim,3 Hee Soon Chung,3 Chang-Hoon Lee3,4 1Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, College of Medicine, Ilsan Paik Hospital, Inje University, Goyang-si, Gyeonggi-Do, 2Department of Radiology, Seoul Metropolitan Government – Seoul National University Boramae Medical Center, 3Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, 4Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Republic of Korea Objectives: Emphysema is one of the prognostic factors for rapid lung function decline in patients with COPD, but the impact of incidentally detected emphysema on population without spirometric abnormalities has not been evaluated. This study aimed to determine whether emphysema detected upon computed tomography (CT screening would accelerate the rate of lung function decline and influence the possibility of future development of airflow limitation in a population without spirometric abnormalities.Materials and methods: Subjects who participated in a routine screening for health checkup and follow-up pulmonary function tests for at least 3 years between 2004 and 2010 were retrospectively enrolled. The percentage of low-attenuation area below −950 Hounsfield units (%LAA−950 was calculated automatically. A calculated value of %LAA−950 that exceeded 10% was defined as emphysema. Adjusted annual lung function decline was analyzed using random-slope, random-intercept mixed linear regression models.Results: A total of 628 healthy subjects within the normal range of spriometric values were included. Multivariable analysis showed that the emphysema group exhibited a faster decline in forced vital capacity (−33.9 versus −18.8

  20. Anti-aging effects of Piper cambodianum P. Fourn. extract on normal human dermal fibroblast cells and a wound-healing model in mice

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    Lee H

    2016-07-01

    Full Text Available Hyunji Lee,1 Youngeun Hong,1 So Hee Kwon,2 Jongsun Park,1 Jisoo Park1 1Department of Pharmacology and Medical Science, Metabolic Diseases and Cell Signaling Laboratory, Research Institute for Medical Sciences, College of Medicine, Chungnam National University, Daejeon, 2Department of Pharmacy, College of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Yonsei University, Incheon, South Korea Background: Aging of skin is associated with environmental factors such as ultraviolet rays, air pollution, gravity, and genetic factors, all of which can lead to wrinkling of skin. Previous reports suggest that the wound repair is impaired by the aging process and strategies to manipulate the age-related wound healing are necessary in order to stimulate repair.Objective: Several traditional plant extracts are well-known for their properties of skin protection and care. Piper cambodianum P. Fourn. (PPF, a member of Piperacecae, is a plant found in Vietnam that might have therapeutic properties. Therefore, the effects of PPF stem and leaf extract on aging process were investigated in vitro and in vivo.Methods: PPF extract dissolved in methanol was investigated using Western blotting, real-time quantitative reverse transcription-polymerase chain reaction, flow cytometry, and cell wound-healing assays. We assessed the anti-aging effect of PPF in mouse using the wound-healing assay. The results were analyzed by Student’s unpaired t-test; *P<0.05 and **P<0.01 were considered to indicate significant and highly significant values, respectively, compared with corresponding controls.Results: PPF treatment demonstrated in vitro and in vivo anti-aging activity. Western blot analysis of PPF-treated normal human dermal fibroblast cells showed a dose-dependent increase in the expression of extracellular matrix genes such as collagen and elastin, but decreased expression of the aging gene matrix metalloproteinase-3. Quantitative polymerase chain reaction showed

  1. Single dose pharmacokinetics of the novel transdermal donepezil patch in healthy volunteers

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    Kim YH

    2015-03-01

    Full Text Available Yo Han Kim,1 Hee Youn Choi,1 Hyeong-Seok Lim,1 Shi Hyang Lee,1 Hae Sun Jeon,1 Donghyun Hong,2 Seong Su Kim,2 Young Kweon Choi,2 Kyun-Seop Bae1 1Department of Clinical Pharmacology and Therapeutics, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Republic of Korea; 2iCure Pharmaceutical lncorporated, Anseong, Gyeonggi-do, Republic of Korea Background: Donepezil is an acetylcholinesterase inhibitor indicated for Alzheimer’s disease. The aim of this randomized, single-blind, placebo-controlled, single-dose, dose-escalation study was to investigate the safety, tolerability, and pharmacokinetics of the donepezil patch in healthy male subjects. Methods: Each healthy male subject received a single transdermal donepezil patch (72 hours patch-on periods of 43.75 mg/12.5 cm2, 87.5 mg/25 cm2, or 175 mg/50 cm2. Serial blood samples were collected up to 312 hours after patch application. The plasma concentrations of donepezil were determined by using a validated liquid chromatography–tandem mass spectrometry method. Pharmacokinetic parameters were obtained by noncompartmental analysis. Tolerability of the patches and performance of the patches (adhesion, skin irritation, residual donepezil content in the patch were assessed throughout the study. Results: The study was completed by 36 healthy subjects. After patch application, the maximal plasma donepezil concentration (Cmax and the area under the curve (AUC increased in a dose-proportional manner. Median time to Cmax was ~74–76 hours (~2–4 hours after patch removal, and mean t1/2ß was ~63.77–93.07 hours. The average donepezil residue in the patch after 72 hours was ~73.9%–86.7% of the loading dose. There were neither serious adverse events nor adverse events that lead to discontinuation. Skin adhesion of the patch was good in 97.2% of the subjects. All skin irritations after patch removal were mild and were resolved during the study period. Conclusion: The donepezil patch

  2. Pharmacokinetic interaction between udenafil and dapoxetine: a randomized, open-labeled crossover study in healthy male volunteers

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    Kim YH

    2015-02-01

    Full Text Available Yo Han Kim,1 Hee Youn Choi,1 Shi Hyang Lee,1 Hae Sun Jeon,1 Hyeong-Seok Lim,1 Mi Young Bahng,2 Kyun-Seop Bae1 1Department of Clinical Pharmacology and Therapeutics, Asan Medical Center, College of Medicine, University of Ulsan, 2Clinical Development Department, Dong-A ST Co, Ltd, Seoul, Republic of Korea Background: “Udenafil” is a phosphodiesterase-5 inhibitor indicated for erectile dysfunction. “Dapoxetine” is a serotonin transport inhibitor indicated for premature ejaculation. The aim of the study reported here was to investigate the pharmacokinetic drug interaction between udenafil and dapoxetine in healthy male subjects. Methods: An open-label, three-treatment, six-sequence, three-period crossover study was performed in healthy male subjects. In varying sequences, each subjects received single oral doses of udenafil 200 mg, dapoxetine 60 mg, and both treatments. The periods were separated by a washout period of 7 days. Serial blood samples were collected up to 48 hours after dosing. The plasma concentrations of udenafil and dapoxetine were determined using a validated liquid chromatography-tandem mass spectrometry method. Pharmacokinetic parameters were obtained by non-compartmental analysis. Tolerability was assessed throughout the study. Results: Twenty-three healthy subjects completed the study. The geometric mean ratios of the area under the plasma concentration–time curve from time 0 to last measurable time point and measured peak plasma concentration for udenafil were 0.923 (90% confidence interval [CI]: 0.863–0.987 and 0.864 (90% CI: 0.789–0.947, respectively. The geometric mean ratios of the area under the plasma concentration–time curve from time 0 to last measurable time point and measured peak plasma concentration for dapoxetine were 1.125 (90% CI: 1.044–1.213 and 0.837 (90% CI: 0.758–0.925, respectively. There were no serious adverse events reported, and none of the subjects dropped out due to adverse events

  3. The influence of dietary sodium content on the pharmacokinetics and pharmacodynamics of fimasartan

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    Gu N

    2016-04-01

    Full Text Available Namyi Gu,1,2 Joo-Youn Cho,3 Kwang-Hee Shin,4 In-Jin Jang,3 Moo-Yong Rhee2,5 1Department of Clinical Pharmacology and Therapeutics, 2Clinical Trial Center, Dongguk University College of Medicine and Ilsan Hospital, Goyang, 3Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, 4Pharmacotherapy & Translational Research Lab., College of Pharmacy, Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu, 5Cardiovascular Center, Dongguk University College of Medicine and Ilsan Hospital, Goyang, Republic of Korea Abstract: A low sodium diet enhances the hemodynamic effect of renin–angiotensin system blockers. It was suggested that the substrates of P-glycoprotein or cytochrome P450 3A4 were reduced on a high sodium diet. This study aimed to investigate the influence of high sodium diet on the pharmacokinetics and pharmacodynamics of fimasartan, which is a substrate of cytochrome P450 3A4 but not P-glycoprotein. The study design was a two-diet, two-period, two-sequence, randomized, open-label, and crossover with 1-week washout for diet. Eligible subjects were fed with either low sodium (50 mEq/day diet or high sodium diet (300 mEq/day for 7 days in the first hospitalization period and the other diet in the second period. On the seventh morning of each period, subjects received a single dose of fimasartan 60 mg in a fasted state. The serial plasma concentrations of fimasartan, serum aldosterone concentration (SAC, and plasma renin activity (PRA were measured for pharmacokinetic–pharmacodynamic analysis. Sixteen subjects completed the study satisfying the compliance test for diets. Although the mean systemic exposure of fimasartan is slightly (≈10% decreased on a high sodium diet, the difference was not statistically or clinically significant (P>0.05. The SAC and PRA after fimasartan administration were highly dependent on their baseline levels. The

  4. Early changes in 25-hydroxyvitamin D levelsand bone markers after monthly risedronatewith cholecalciferol in Korean patients with osteoporosis

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    Chung HY

    2013-05-01

    Full Text Available Ho Yeon Chung,1 Jawon Koo,1 Su Kyoung Kwon,2 Moo-IL Kang,3 Seong-Hwan Moon,4 Jin-Young Park,5 Chan Soo Shin,6 Byung-Koo Yoon,7 Hyun-Koo Yoon,8 Jae-Suk Chang,9 Yoon-Sok Chung,10 Hyoung-Moo Park111Department of Internal Medicine, Kyung Hee University, 2Department of Statistics, 3Department of Internal Medicine, Catholic University of Korea, 4Department of Orthopedics, Yonsei University, 5Department of Orthopedics, Konkuk University, 6Department of Internal Medicine, Seoul National University, 7Department of Obstetrics and Gynecology, Sungkyunkwan University, 8Department of Internal Medicine, Kwandong University, 9Department of Orthopedics, University of Ulsan, Seoul, South Korea; 10Department of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, South Korea; 11Department of Obstetrics and Gynecology, Chung-Ang University, Seoul, South KoreaPurpose: This study investigated the efficacy and safety of monthly risedronate, with and without cholecalciferol, on 25-hydroxyvitamin D (25[OH]D levels and bone markers in Korean patients with osteoporosis.Methods: A randomized, double-blinded, prospective, 16-week clinical trial was conducted in ten hospitals. A total of 150 subjects with osteoporosis were randomized to one of the two treatment groups: RSDM+ (monthly risedronate 150 mg and cholecalciferol 30,000 IU combined in a single pill, n = 74 or RSDM (monthly risedronate 150 mg alone, n = 76. We measured serum levels of 25-hydroxyvitamin D (25[OH]D, parathyroid hormone (PTH, and bone markers, as well as performing muscle-function tests at baseline and after 16 weeks of treatment.Results: After 16 weeks, serum 25(OHD levels significantly increased from 17.8 to 26.8 ng/mL in the RSDM+ group, but did not change in the RSDM group. The RSDM+ group exhibited significantly decreased serum PTH from 46 to 36.7 pg/mL, while the RSDM group showed a tendency for PTH to increase from 38 to 40.6 pg/mL. In both groups, serum bone

  5. Enhancement of the dissolution rate and bioavailability of fenofibrate by a melt-adsorption method using supercritical carbon dioxide

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    Cha KH

    2012-10-01

    Full Text Available Kwang-Ho Cha,1,3 Kyung-Jin Cho,3 Min-Soo Kim,4 Jeong-Soo Kim,3 Hee Jun Park,1,3 Junsung Park,1,3 Wonkyung Cho,1,3 Jeong-Sook Park,3 Sung-Joo Hwang1,21Yonsei Institute of Pharmaceutical Sciences, 2College of Pharmacy, Yonsei University, Incheon, Republic of Korea; 3College of Pharmacy, Chungnam National University, Daejeon, Republic of Korea; 4Department of Pharmaceutical Engineering, Inje University, Gimhae, Republic of KoreaBackground: The aim of this study was to enhance the bioavailability of fenofibrate, a poorly water-soluble drug, using a melt-adsorption method with supercritical CO2.Methods: Fenofibrate was loaded onto Neusilin® UFL2 at different weight ratios of fenofibrate to Neusilin UFL2 by melt-adsorption using supercritical CO2. For comparison, fenofibrate-loaded Neusilin UFL2 was prepared by solvent evaporation and hot melt-adsorption methods. The fenofibrate formulations prepared were characterized by differential scanning calorimetry, powder x-ray diffractometry, specific surface area, pore size distribution, scanning electron microscopy, and energy-dispersive x-ray spectrometry. In vitro dissolution and in vivo bioavailability were also investigated.Results: Fenofibrate was distributed into the pores of Neusilin UFL2 and showed reduced crystal formation following adsorption. Supercritical CO2 facilitated the introduction of fenofibrate into the pores of Neusilin UFL2. Compared with raw fenofibrate, fenofibrate from the prepared powders showed a significantly increased dissolution rate and better bioavailability. In particular, the area under the drug concentration-time curve and maximal serum concentration of the powders prepared using supercritical CO2 were 4.62-fold and 4.52-fold greater than the corresponding values for raw fenofibrate.Conclusion: The results of this study highlight the usefulness of the melt-adsorption method using supercritical CO2 for improving the bioavailability of fenofibrate.Keywords: fenofibrate

  6. Wildfire and abrupt ecosystem disruption on California's Northern Channel Islands at the Ållerød-Younger Dryas boundary (13.0-12.9 ka)

    Science.gov (United States)

    Kennett, D. J.; Kennett, J. P.; West, G. J.; Erlandson, J. M.; Johnson, J. R.; Hendy, I. L.; West, A.; Culleton, B. J.; Jones, T. L.; Stafford, Thomas W., Jr.

    2008-12-01

    ., Mayewski, P.A., Montgomery, J., Poreda, R., Darrah, T., Que Hee, S.S., Smith, A.R., Stich, A., Topping, W., Wittke, J.H. Wolbach, W.S., 2007. Evidence for an extraterrestrial impact 12,900 years ago that contributed to the megafaunal extinctions and Younger Dryas cooling. Proceedings of the National Academy of Sciences 104, 16016-16021.].

  7. A comparison of folate status in women of child-bearing age in Korea and in the United States

    Directory of Open Access Journals (Sweden)

    Hyun T

    2012-07-01

    Full Text Available Taisun Hyun,1 Suguna Badiga,2 Han Byul Jang,1 Young-Hee Han,1 Chandrika J Piyathilake21Department of Food and Nutrition, Chungbuk National University, Cheongju, Korea; 2Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL, USABackground: Even though several studies have demonstrated that periconceptional supplementation with folic acid (FA reduces the occurrence of neural tube defects, FA fortification has been a topic of intense debate due to the possible adverse effects of higher folate status on several health conditions. Several countries, including Korea, have been indecisive as to whether fortification is warranted or not. It is therefore helpful for these countries to compare folate concentrations in their populations with populations exposed to mandatory FA fortification.Purpose: To evaluate the differences in the distribution of circulating concentrations of folate in Korea and the United States (US at different time points.Methods: The Korean study populations consisted of women of child-bearing age recruited in 1999 and in 2009. The US study populations consisted of women of child-bearing age recruited in the post FA fortification era (2005 and 2009. Plasma and red blood cell (RBC folate concentrations were measured using the Lactobacillus casei microbiological assay.Results: The percentage of US women with neural tube defect-protective levels of RBC folate was significantly higher compared to Korean women in 1999 and 2009. However, in 2009, when FA supplements became readily available for Koreans, 50% of Korean women in the study achieved the neural tube defect-protective level of RBC folate; 11% of them demonstrating supraphysiologic concentrations of plasma folate. Even though FA fortification in the US resulted in more than 80of women achieving >400 ng/mL of RBC folate by 2009, nearly 50% also demonstrated having supraphysiologic concentrations of plasma folate, which prompted some researchers to

  8. Integrative assessment of hydrological, ecological, and economic systems for water resources management at river basin scale

    Institute of Scientific and Technical Information of China (English)

    Xianglian LI; Xiusheng YANG; Qiong GAO; Yu LI; Suocheng DONG

    2009-01-01

    This study presents a basin-scale integrative hydrological, ecological, and economic (HEE) modeling system, aimed at evaluating the impact of resources management, especially agricultural water resources management, on the sustainability of regional water resources. The hydrological model in the modeling system was adapted from SWAT, the Soil and Water Assessment Tool, to simulate the water balance in terms of soil moisture, evapotranspiration, and streamflow. An ecologi-cal model was integrated into the hydrological model to compute the ecosystem production of biomass production and yield for different land use types. The economic model estimated the monetary values of crop production and water productivity over irrigated areas. The modeling system was primarily integrated and run on a Windows platform and was able to produce simulation results at daily time steps with a spatial resolution of hydrological response unit (HRU). The modeling system was then calibrated over the period from 1983 to 1991 for the upper and middle parts of the Yellow River basin, China.Calibration results showed that the efficiencies of the modeling system in simulating monthly streamflow over 5hydrological stations were from 0.54 to 0.68 with an average of 0.64, indicating an acceptable calibration.Preliminary simulation results from 1986 to 1995 revealed that water use in the study region has largely reduced the streamflow in many parts of the area except for that in the riverhead. Spatial distribution of biomass production, and crop yield showed a strong impact of irrigation on agricultural production. Water productivity over irrigated cropland ranged from 1 to 1640 USD/(ha.mm 1), indicat-ing a wide variation of the production conditions within the study region and a great potential in promoting water use efficiency in low water productivity areas. Generally,simulation results from this study indicated that the modeling system was capable of tracking the temporal and spatial

  9. PENGARUH LINGKUNGAN SUHU TINGGI DAN SUHU RENDAH TERHADAP KONSUMSI ZAT GIZI DAN STATUS GIZI ORANG DEWASA

    Directory of Open Access Journals (Sweden)

    Fithia Dyah Puspitasari

    2016-09-01

    Full Text Available ABSTRACTThe imbalance nutrition intake for a long term period can cause changes in weight, body composition andmay alter health problem. The environment temperature can affect the 24 Hours Energy Expenditure (24-hEE magnitude. This research was aimed to investigate the differences of adult's nutrient intake pattern inhigh-temperature and low-temperature area. Research was held in high-temperature area (Jakarta and lowtemperaturearea (Tawangmangu. Frequency distribution analysis was done to obtain the respondentcharacteristics, while bivariat test was done to determine the difference of energy consumption rate andnutritions. The results showed that the subjects in high-temperature area consumed higher total protein,total vitamin B2 and total calcium than the subjects in low-temperature area. Subject in low-temperaturearea consumed more partial calcium compare to subjects in high-temperature area. There was a signifiCantdifference in average of total vitamin A intake between less and overweight group (p=0,049; normal andoverweight group (p=0,007 and between overweight and obese group (p=0,004.Keywords: Nutrient intake, nutrition status, environment temperature ABSTRAKKetidakseimbangan asupan zat gizi pada jangka waktu yang lama mengakibatkan perubahan berat badan,komposisi tubuh dan memungkinan timbulnya gangguan kesehatan. Suhu lingkungan mempengaruhibesaran 24 Hours Energy Expenditure (24-h EE. Penelitian ini bertujuan untuk mengetahui perbedaan polakonsumsi zat gizi orang dewasa di lingkungan bersuhu tinggi dan lingkungan bersuhu rendah. Penelitiandilakukan di area bersuhu tinggi (Jakarta dan area bersuhu rendah (Tawangmangu. Analisis distribusifrekuensi dilakukan untuk mengetahui karakteristik responden sedangkan uji bivariat dilakukan untukmengetahui beda jumlah konsumsi energi dan zat gizi. Hasil penelitian menunjukkan bahwa subyek padaarea suhu tinggi mengonsumsi protein total, vitamin B2 total dan kalsium total lebih banyak

  10. Raspberry-like poly(γ-glutamic acid hydrogel particles for pH-dependent cell membrane passage and controlled cytosolic delivery of antitumor drugs

    Directory of Open Access Journals (Sweden)

    Cho SH

    2016-10-01

    Full Text Available Sun-Hee Cho,1,* Ji Hyeon Hong,2,* Young-Woock Noh,1 Eunji Lee,2 Chang-Soo Lee,3 Yong Taik Lim1 1SKKU Advanced Institute of Nanotechnology, School of Chemical Engineering, Sungkyunkwan University, Suwon, Gyeonggi-do, 2Graduate School of Analytical Science and Technology, Chungnam National University, 3Hazards Monitoring Bionano Research Center, Korea Research Institute of Bioscience and Biotechnology, Yuseong-gu, Daejeon, Republic of Korea *These authors contributed equally to this work Abstract: In this research, we synthesized bioderived poly(amino acid hydrogel particles that showed pH-dependent membrane-disrupting properties and controlled cytosolic delivery of antitumor drugs. Poly(γ-glutamic acid (γ-PGA that has been produced extensively using bacteria, especially those of Bacillus subtilis species, was modified with cholesterol (γ-PGA/Chol, and the γ-PGA/Chol conjugates were used to form polymeric nanoparticles the size of 21.0±1.1 nm in aqueous solution. When the polymeric nanoparticles were mixed with doxorubicin (Dox, raspberry-like hydrogel particles (RBHPs were formed by the electrostatic interaction between the cationically charged Dox and the anionically charged nanoparticles. The average size and surface charge of the RBHPs in aqueous solution were 444.9±122.5 nm and -56.44 mV, respectively. The loaded amount of Dox was approximately 63.9 µg/mg of RBHPs. The RBHPs showed controlled drug release behavior in both in vitro and ex vivo cell-based experiments. Through fluorescence microscopy and fluorescence-activated cell sorting, the cellular uptake of RBHPs into human cervical cancer cells (HeLa was analyzed. The cytotoxic effect, evaluated by the methyl tetrazolium salt assay, was dependent on both the concentration of RBHPs and the treatment time. The pH-dependent membrane-disrupting properties of the RBHPs and the subsequent cytosolic delivery of Dox were evaluated using a standard hemolysis assay. Upon an increase in

  11. Recommendations for competency in allergy training for undergraduates qualifying as medical practitioners: a position paper of the world allergy organization.

    Science.gov (United States)

    Potter, Paul C; Warner, John O; Pawankar, Ruby; Kaliner, Michael A; Del Giacco, Sergio; Rosenwasser, Lanny

    2009-08-01

    The Council acknowledges specific comments from: The American Academy of Allergy, Asthma and Immunology (AAAAI) (Amal H Assa'ad); The American College of Allergy, Asthma and Immunology (ACAAI) (Mark Dykewicz, D. Betty Lew, Bryan L. Martin); The Argentine Association of Allergy and Immunology (Ledit RF Ardusso); The Argentine Society of Allergy and Immunopathology (Estrella Asayag); The Australasian Society of Clinical Immunology and Allergy (ASCIA) (Jill Smith); The British Society for Allergy and Clinical Immunology (Stephen Durham); The Brazilian Society of Allergy and Immunopathology (Nelson Rosario); The Bulgarian Society of Allergology (Vasil Dimitrov); The Canadian Society of Allergy and Clinical Immunology (CSACI) (Richard Warrington); The Chilean Society of Allergy and Immunology (Jessica Salinas); The Chinese Society of Allergology (Zhang Hongyu, Yin Jia); The Czech Society of Allergology and Clinical Immunology (Jiri Litzman); The Danish Society of Allergology (Lone Winther, Peter Plaschke); The Egyptian Society of Allergy and Clinical Immunology (Kamal Maurice Hanna); The Egyptian Society of Pediatric Allergy and Immunology (Yehia El-Gamal); The German Society for Allergy and Clinical Immunology (Thilo Jakob, Claus Bachert, Bernhard Przybilla); The Hungarian Society of Allergology and Clinical Immunology (Kristof Nekam); The Icelandic Society of Allergy and Clinical Immunology (Björn R. Lúđvíksson); The Italian Association of Territorial and Hospital Allergists (Riccardo Asero); The Italian Society of Allergy and Clinical Immunology (Luigi Fontana); The Japanese Society of Allergology (Sankei Nishima); The Korean Academy of Asthma Allergy and Clinical Immunology (Joon Sung Lee, Hae-Sim Park); The Latvian Association of Allergists (Ieva Cirule); The Lebanese Society of Allergy & Immunology (Fares Zaitoun); The Mongolian Society of Allergology (S. Munkhbayarlakh); The Allergy and Clinical Immunology Society (Singapore) (Chng Hiok Hee); The Allergy

  12. Silver nanoparticles cause complications in pregnant mice

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    Zhang XF

    2015-11-01

    Full Text Available Xi-Feng Zhang,1,2 Jung-Hyun Park,1 Yun-Jung Choi,1 Min-Hee Kang,1 Sangiliyandi Gurunathan,1 Jin-Hoi Kim11Department of Animal Biotechnology, Konkuk University, Seoul, Republic of Korea; 2College of Biological and Pharmaceutical Engineering, Wuhan Polytechnic University, Wuhan, People’s Republic of ChinaBackground: Silver nanoparticles (AgNPs have attracted much interest and have been used for antibacterial, antifungal, anticancer, and antiangiogenic applications because of their unique properties. The increased usage of AgNPs leads to a potential hazard to human health. However, the potential effects of AgNPs on animal models are not clear. This study was designed to investigate the potential impact of AgNPs on pregnant mice.Methods: The synthesis of AgNPs was performed using culture extracts of Bacillus cereus. The synthesized AgNPs were characterized by X-ray diffraction, Fourier transform infrared spectroscopy, and transmission electron microscopy. AgNPs were administrated into pregnant mice via intravenous infusion at 1.0 mg/kg doses at 6.5 days postcoitum (dpc. At 13.5, 15.5, and 17.5 dpc, the pregnant mice were euthanized, and the embryo and placenta were isolated. The meiotic status of oocytes was evaluated. DNA methylation studies were performed, and aberrant imprinting disrupted fetal, placental, and postnatal development. Quantitative real-time polymerase chain reaction analysis and Western blot were used to analyze various gene expressions.Results: The synthesized AgNPs were uniformly distributed and were spherical in shape with an average size of 8 nm. AgNPs exposure increased the meiotic progression of female germ cells in the fetal mouse ovaries, and maternal AgNP exposure significantly disrupted imprinted gene expression in 15.5 dpc embryos and placentas, such as Ascl2, Snrpn, Kcnq1ot1, Peg3, Zac1, H19, Igf2r, and Igf2; DNA methylation studies revealed that AgNPs exposure significantly altered the methylation levels of

  13. Nanoparticulated docetaxel exerts enhanced anticancer efficacy and overcomes existing limitations of traditional drugs

    Directory of Open Access Journals (Sweden)

    Choi J

    2015-09-01

    Full Text Available Jinhyang Choi,1,2 Eunjung Ko,1 Hye-Kyung Chung,3 Jae Hee Lee,1 Eun Jin Ju,1 Hyun Kyung Lim,4 Intae Park,1 Kab-Sig Kim,5 Joo-Hwan Lee,5 Woo-Chan Son,6 Jung Shin Lee,1,7 Joohee Jung,1,4 Seong-Yun Jeong,1,2 Si Yeol Song,1,8 Eun Kyung Choi1,3,8 1Institute for Innovative Cancer Research, 2Asan Institute for Life Sciences, 3Center for Development and Commercialization of Anti-cancer Therapeutics, 4College of Pharmacy, Duksung Women’s University, 5Bio-Synectics, 6Department of Pathology, 7Department of Internal Medicine, 8Department of Radiation Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea Abstract: Nanoparticulation of insoluble drugs improves dissolution rate, resulting in increased bioavailability that leads to increased stability, better efficacy, and reduced toxicity of drugs. Docetaxel (DTX, under the trade name Taxotere™, is one of the representative anticancer chemotherapeutic agents of this era. However, this highly lipophilic and insoluble drug has many adverse effects. Our novel and widely applicable nanoparticulation using fat and supercritical fluid (NUFS™ technology enabled successful nanoscale particulation of DTX (Nufs-DTX. Nufs-DTX showed enhanced dissolution rate and increased aqueous stability in water. After confirming the preserved mechanism of action of DTX, which targets microtubules, we showed that Nufs-DTX exhibited similar effects in proliferation and clonogenic assays using A549 cells. Interestingly, we observed that Nufs-DTX had a greater in vivo tumor growth delay effect on an A549 xenograft model than Taxotere™, which was in agreement with the improved drug accumulation in tumors according to the biodistribution result, and was caused by the enhanced permeability and retention (EPR effect. Although both Nufs-DTX and Taxotere™ showed negative results for our administration dose in the hematologic toxicity test, Nufs-DTX showed much less toxicity than Taxotere™ in

  14. Biodistribution of newly synthesized PHEA-based polymer-coated SPION in Sprague Dawley rats as magnetic resonance contrast agent

    Directory of Open Access Journals (Sweden)

    Park J

    2013-10-01

    Full Text Available Junsung Park,1,2,* Wonkyung Cho,1,2,* Hee Jun Park,1,2 Kwang-Ho Cha,1,2 Dae-Chul Ha,2,5 Youn-Woong Choi,5 Ha-Young Lee,3 Sun-Hang Cho,5 Sung-Joo Hwang1,4 1Yonsei Institute of Pharmaceutical Sciences, Yonsei University, Incheon, Republic of Korea; 2College of Pharmacy, Chungnam National University, Daejeon, Republic of Korea; 3Biomaterials Laboratory, Korea Research Institutes of Chemical Technology, Daejeon, Republic of Korea; 4College of Pharmacy, Yonsei University, Incheon, Republic of Korea; 5Korea United Pharm Inc, Seoul, Republic of Korea *These authors contributed equally to this work Objectives: The purpose of this study was to observe the pharmacokinetic behavior of newly synthesized biocompatible polymers based on polyhydroxyethylaspartamide (PHEA to be used to coat an iron oxide core to make superparamagnetic iron oxide nanoparticles (SPION. Materials and methods: The isotopes [14C] and [59Fe] were used to label the polymer backbone (CLS and iron oxide core (FLS, respectively. In addition, unradiolabeled cold superparamagnetic iron oxide nanoparticles (SPION/ULS were synthesized to characterize particle size by dynamic light scattering, morphology by transmission electron microscopy, and in vivo magnetic resonance imaging (MRI. CLS and FLS were used separately to investigate the behavior of both the synthesized polymer and [Fe] in Sprague Dawley (SD rats, respectively. Because radioactivity of the isotopes was different by β for CLS and γ for FLS, synthesis of the samples had to be separately prepared. Results: The mean particle size of the ULS was 66.1 nm, and the biodistribution of CLS concentrations in various organs, in rank order of magnitude, was liver > kidney > small intestine > other. The biodistribution of FLS concentrations was liver > spleen > lung > other. These rank orders show that synthesized SPION mainly accumulates in the liver. The differences in the distribution were caused by the SPION metabolism. Radiolabeled

  15. Sleep and cognitive problems in patients with attention-deficit hyperactivity disorder

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    Lee HK

    2014-09-01

    Full Text Available Hae Kook Lee, Jong-Hyun Jeong, Na-Young Kim, Min-hyeon Park, Tae-Won Kim, Ho-Jun Seo, Hyun-Kook Lim, Seung-Chul Hong, Jin-Hee Han Department of Psychiatry, College of Medicine, The Catholic University of Korea, Seoul, Korea Objectives: Attention-deficit hyperactivity disorder (ADHD is characterized by inattentive and impulsive behavior. Many ADHD patients reportedly have cognitive dysfunction and sleep problems, including longer sleep latency, lower sleep efficiency, and shorter total sleep time. The purpose of this study was to examine neurocognitive functions and nocturnal sleep parameters in patients with ADHD, using a cognitive function test and actigraphy.Methods: Subjects included 37 male patients with ADHD and 32 controls (7–12 years of age. For each participant, we determined intelligence quotient (IQ and administered the Matching Familiar Figures Test (MFFT and 72-hour actigraphy. The relationships between sleep parameters and cognitive functions were assessed.Results: ADHD patients significantly differed from controls in several cognitive functions and sleep variables. In the MFFT, response error rate (P<0.001 and error counts (P=0.003 were significantly increased in ADHD patients compared with control children. MFFT response latency was significantly shorter in ADHD patients than in controls (P<0.001. In addition, sleep latency (P=0.01, wake after sleep onset (WASO (P<0.001, and fragmentation index (P<0.001 were evaluated by actigraphy and found to be significantly increased in patients with ADHD compared with controls. However, no significant differences in total sleep time or sleep efficiency were observed. WASO and response error rates were positively correlated in patients with ADHD (rho =0.52, P=0.012. Furthermore, fragmentation index sleep variables were significantly positively correlated with response error (rho =0.44, P=0.008 and response latency rates (rho =0.4, P=0.018 in the MFFT. Reaction error rate was significantly

  16. Agricultural Fragility Estimates Subjected to Volcanic Ash Fall Hazards

    Science.gov (United States)

    Ham, H. J.; Lee, S.; Choi, S. H.; Yun, W. S.

    2015-12-01

    Agricultural Fragility Estimates Subjected to Volcanic Ash Fall Hazards Hee Jung Ham1, Seung-Hun Choi1, Woo-Seok Yun1, Sungsu Lee2 1Department of Architectural Engineering, Kangwon National University, Korea 2Division of Civil Engineering, Chungbuk National University, Korea ABSTRACT In this study, fragility functions are developed to estimate expected volcanic ash damages of the agricultural sector in Korea. The fragility functions are derived from two approaches: 1) empirical approach based on field observations of impacts to agriculture from the 2006 eruption of Merapi volcano in Indonesia and 2) the FOSM (first-order second-moment) analytical approach based on distribution and thickness of volcanic ash observed from the 1980 eruption of Mt. Saint Helens and agricultural facility specifications in Korea. Fragility function to each agricultural commodity class is presented by a cumulative distribution function of the generalized extreme value distribution. Different functions are developed to estimate production losses from outdoor and greenhouse farming. Seasonal climate influences vulnerability of each agricultural crop and is found to be a crucial component in determining fragility of agricultural commodities to an ash fall. In the study, the seasonality coefficient is established as a multiplier of fragility function to consider the seasonal vulnerability. Yields of the different agricultural commodities are obtained from Korean Statistical Information Service to create a baseline for future agricultural volcanic loss estimation. Numerically simulated examples of scenario ash fall events at Mt. Baekdu volcano are utilized to illustrate the application of the developed fragility functions. Acknowledgements This research was supported by a grant 'Development of Advanced Volcanic Disaster Response System considering Potential Volcanic Risk around Korea' [MPSS-NH-2015-81] from the Natural Hazard Mitigation Research Group, Ministry of Public Safety and Security of

  17. The association between combined non-cystic fibrosis bronchiectasis and lung cancer in patients with chronic obstructive lung disease

    Directory of Open Access Journals (Sweden)

    Kim YW

    2015-05-01

    Full Text Available Yeon Wook Kim,1 Kwang-Nam Jin,2 Eun Young Heo,3 Sung Soo Park,3 Hee Soon Chung,3 Deog Kyeom Kim31Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea; 2Department of Radiology, Seoul National University College of Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Republic of Korea; 3Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Republic of KoreaBackground: Whereas the epidemiological association between lung cancer and chronic obstructive pulmonary disease (COPD, a chronic inflammatory respiratory disease, is well known, limited studies have examined the association between lung cancer and non-cystic fibrosis bronchiectasis, a representative chronic airway inflammatory disease. This study evaluated the association between bronchiectasis and lung cancer in patients with COPD.Methods: A matched case–control study was conducted in a referral hospital in South Korea. Among COPD patients with moderate to very severe airflow limitation (forced expiratory volume in one second/forced vital capacity <0.7 and forced expiratory volume in one second ≤70% [% predicted] who underwent chest computed tomography (CT between January 1, 2010 and May 30, 2013, patients with lung cancer and controls matched for age, sex, and smoking history were selected. The risk of lung cancer was assessed according to the presence of underlying bronchiectasis confirmed by chest CT.Results: The study enrolled 99 cases and 198 controls. Combined bronchiectasis on chest CT was inversely associated with the risk of lung cancer compared with controls (odds ratio [OR] 0.25, 95% confidence interval [CI] 0.12–0.52, P<0.001. Significant associations were found in

  18. Basic fibroblast growth factor induces matrix metalloproteinase-13 via ERK MAP kinase-altered phosphorylation and sumoylation of Elk-1 in human adult articular chondrocytes

    Directory of Open Access Journals (Sweden)

    Hee-Jeong Im

    2009-10-01

    Full Text Available Hee-Jeong Im,1–4 Andrew D Sharrocks,5 Xia Lin,6 Dongyao Yan,1 Jaesung Kim,1 Andre J van Wijnen,7 Robert A Hipskind81Departments of Biochemistry, 2Internal Medicine, 3Section of Rheumatology, Orthopedic Surgery, 4Rush University Medical Center, and Department of Bioengineering; University of Illinois at Chicago, IL USA; 5Faculty of Life Sciences, University of Manchester, Oxford Rd, Manchester, UK; 6Michael D DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas, USA; 7Department of Cell Biology, University of Massachusetts Medical School, Worcester, MA, USA; 8Institute De Genetique Moleculaire de Montpellier, FranceAbstract: Degradation of the extracellular matrix (ECM by matrix metalloproteinases (MMPs and release of basic fibroblast growth factor (bFGF are principal aspects of the pathology of osteoarthritis (OA. ECM disruption leads to bFGF release, which activates the extracellular signal-regulated kinase/mitogen-activated protein kinase (ERK/MAPK pathway and its downstream target the Ets-like transcription factor Elk-1. Previously we demonstrated that the bFGF-ERK-Elk-1 signaling axis is responsible for the potent induction of MMP-13 in human primary articular chondrocytes. Here we report that, in addition to phosphorylation of Elk-1, dynamic posttranslational modification of Elk-1 by small ubiquitin-related modifier (SUMO serves as an important mechanism through which MMP-13 gene expression is regulated. We show that bFGF activates Elk-1 mainly through the ERK pathway and that increased phosphorylation of Elk-1 is accompanied by decreased conjugation of SUMO to Elk-1. Reporter gene assays reveal that phosphorylation renders Elk-1 competent for induction of MMP-13 gene transcription, while sumoylation has the opposite effect. Furthermore, we demonstrate that the SUMO-conjugase Ubc9 acts as a key mediator for Elk-1 sumoylation. Taken together, our results suggest that sumoylation antagonizes the phosphorylation

  19. Green synthesis of multifunctional silver and gold nanoparticles from the oriental herbal adaptogen: Siberian ginseng

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    Abbai R

    2016-07-01

    Full Text Available Ragavendran Abbai,1,* Ramya Mathiyalagan,1,* Josua Markus,1 Yeon-Ju Kim,2 Chao Wang,2 Priyanka Singh,2 Sungeun Ahn,2 Mohamed El-Agamy Farh,2 Deok Chun Yang1,2 1Ginseng Bank, Graduate School of Biotechnology, 2Department of Oriental Medicinal Biotechnology, College of Life Sciences, Kyung Hee University, Yongin, Republic of Korea *These authors contributed equally to this work Abstract: Pharmacologically active stem of the oriental herbal adaptogen, Siberian ginseng, was employed for the ecofriendly synthesis of Siberian ginseng silver nanoparticles (Sg-AgNPs and Siberian ginseng gold nanoparticles (Sg-AuNPs. First, for metabolic characterization of the sample, liquid chromatography-tandem mass spectrometry analysis (indicated the presence of eleutherosides A and E, total phenol content, and total reducing sugar were analyzed. Second, the water extract of the sample mediated the biological synthesis of both Sg-AgNPs and Sg-AuNPs that were crystalline face-centered cubical structures with a Z-average hydrodynamic diameter of 126 and 189 nm, respectively. Moreover, Fourier transform infrared analysis indicated that proteins and aromatic hydrocarbons play a key role in the formation and stabilization of Sg-AgNPs, whereas phenolic compounds accounted for the synthesis and stability of Sg-AuNPs. 3-(4,5-Dimethyl-2-thiazolyl-2,5-diphenyl-2H tetrazolium bromide (MTT assay determined that Sg-AgNPs conferred strong cytotoxicity against MCF7 (human breast cancer cell line and was only slightly toxic to HaCaT (human keratinocyte cell line at 10 µg·mL-1. However, Sg-AuNPs did not display cytotoxic effects against both of the cell lines. The disc diffusion assay indicated a dose-dependent increase in the zone of inhibition of Staphylococcus aureus (ATCC 6538, Bacillus anthracis (NCTC 10340, Vibrio parahaemolyticus (ATCC 33844, and Escherichia coli (BL21 treated with Sg-AgNPs, whereas Sg-AuNPs did not show inhibitory activity. In addition, the 2,2-diphenyl-1

  20. Tissue distribution and excretion kinetics of orally administered silica nanoparticles in rats

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    Lee JA

    2014-12-01

    Full Text Available Jeong-A Lee,1 Mi-Kyung Kim,1 Hee-Jeong Paek,1 Yu-Ri Kim,2 Meyoung-Kon Kim,2 Jong-Kwon Lee,3 Jayoung Jeong,3 Soo-Jin Choi1 1Department of Food Science and Technology, Seoul Women’s University, Seoul, Republic of Korea; 2Department of Biochemistry and Molecular Biology, Korea University Medical School and College, Seoul, Republic of Korea; 3Toxicological Research Division, National Institute of Food and Drug Safety Evaluation, Chungchungbuk–do, Republic of Korea Purpose: The effects of particle size on the tissue distribution and excretion kinetics of silica nanoparticles and their biological fates were investigated following a single oral administration to male and female rats. Methods: Silica nanoparticles of two different sizes (20 nm and 100 nm were orally administered to male and female rats, respectively. Tissue distribution kinetics, excretion profiles, and fates in tissues were analyzed using elemental analysis and transmission electron microscopy. Results: The differently sized silica nanoparticles mainly distributed to kidneys and liver for 3 days post-administration and, to some extent, to lungs and spleen for 2 days post-administration, regardless of particle size or sex. Transmission electron microscopy and energy dispersive spectroscopy studies in tissues demonstrated almost intact particles in liver, but partially decomposed particles with an irregular morphology were found in kidneys, especially in rats that had been administered 20 nm nanoparticles. Size-dependent excretion kinetics were apparent and the smaller 20 nm particles were found to be more rapidly eliminated than the larger 100 nm particles. Elimination profiles showed 7%–8% of silica nanoparticles were excreted via urine, but most nanoparticles were excreted via feces, regardless of particle size or sex. Conclusion: The kidneys, liver, lungs, and spleen were found to be the target organs of orally-administered silica nanoparticles in rats, and this organ

  1. Supplier Partnership Strategy and Global Competitiveness: A Case of Samsung Electronics

    Directory of Open Access Journals (Sweden)

    Jangwoo Lee

    2015-11-01

    Full Text Available Samsung Group has accelerated its management innovation process, following the announcement of ‘New Management’ by the CEO Lee Kun-Hee. Particular attention must be paid to the smart-phone business of Samsung Electronics, which is the core company of the Samsung Group. In 2009, as Apple entered into the Korean market, the domestic smart-phone market faced the so called ‘Apple Shock’ due to its choice of a monopolistic and closed operating system. In response, Samsung Electronics introduced the innovative Galaxy series, replacing the old model of Omnia series. This move reaped dramatic success by dominating the world smart-phone market. Samsung Electronics ranked first in the 2012 world smart-phone market, and in 2013 it sold over 300 million devices for the first time in history, thereby solidifying the number one spot with a market share of 32.3%. Samsung Electronics’ achievement in its management innovation process was successful, due to its internal innovation and its partnership with sub-suppliers. Samsung Electronics strengthened its supplier partnership strategy, which in turn, led to an internalization of subparts assembly and process technology. By conducting the final assembly process on its own, it established the global supply chain that accompanies a high level of efficiency and operational elasticity. Samsung Electronics successfully systemized several hundred suppliers into an effective partnership and created an eco system where cooperation and competition can co-exist in its supply chain network. In sum, Samsung Electronics has successfully created the Samsung Production System that brings an economy of scale and allows prompt response. On the other hand, Apple did not get involved with subparts production, besides design and product design. This research identifies the effectiveness of Samsung Electronics’ supplier partnerships in its global competitiveness by examining characteristics of supplier partnership

  2. Effectiveness of elastic band-type ankle–foot orthoses on postural control in poststroke elderly patients as determined using combined measurement of the stability index and body weight-bearing ratio

    Directory of Open Access Journals (Sweden)

    Kim JH

    2015-11-01

    Full Text Available Jong Hyun Kim, Woo Sang Sim, Byeong Hee Won Usability Evaluation Technology Center, Advanced Biomedical and Welfare R&D Group, Korea Institute of Industrial Technology, Cheonan-si, Chungcheongnam-do, South Korea Purpose: Poor recovery of postural stability poststroke is the primary cause of impairment in activities and social participation in elderly stroke survivors. The purpose of our study was to experimentally evaluate the effectiveness of our new elastic ankle–foot orthosis (AFO, compared to a traditional AFO fabricated with hard plastic, in improving postural stability in elderly chronic stroke survivors. Patients and methods: Postural stability was evaluated in ten chronic stroke patients, 55.7±8.43 years old. Postural stability was evaluated using the standardized methods of the Biodex Balance System combined with a foot pressure system, under three experimental conditions, no AFO, rigid plastic AFO, and elastic AFO (E-AFO. The following dependent variables of postural stability were analyzed: plantar pressure under the paretic and nonparetic foot, area of the center of balance (COB and % time spent in each location, distance traveled by the COB away from the body center, distance traveled by the center of pressure, and calculated index of overall stability, as well as indices anterior–posterior and medial–lateral stability. Results: Both AFO designs improved all indices of postural stability. Compared to the rigid plastic AFO, the E-AFO produced additional positive effects in controlling anterior–posterior body sway, equalizing weight bearing through the paretic and nonparetic limbs, and restraining the displacement of the center of pressure and of the COB. Conclusion: Based on our outcomes, we recommend the prescription of E-AFOs as part of a physiotherapy rehabilitation program to promote recovery of postural stability poststroke. When possible, therapeutic outcomes should be documented using the Biodex Balance System and

  3. Utilization of AGN-201K for Education and Research in Korea

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Myung-Hyun [Department of Nuclear Engineering, Kyung Hee University, KHU Reactor Research and Education Center, Kiheung, Yongin, Gyeonggi-do, 446-701 (Korea, Republic of)

    2011-07-01

    A zero power reactor, AGN-201K has been operated in Kyung Hee University since 1982 and it was refurbished extensively three years ago. In 2008, Reactor Research and Education Center (RREC) was established for student training and research. The primary mission of RREC is an educational service for nuclear engineering students. Since January 2009, short courses were provided 15 times to 160 students from 7 universities. This course has been an one-week dormitory housing program in the name of Reactor Experiment and was designed as an advanced course customized to undergraduate senior-level. It has introductory session, safety guide session, concluding presentation session with six experiment sessions; reactor operation and control, measurement of period for reactivity, criticality approach, rod worth measurement, measurement of temperature feedback coefficient and thermal flux measurement with neutron activation analysis (NAA). As a R and D effort for future experimental courses, RREC is now seeking for the possibility of reactor utilization for prompt gamma activation analysis, NAA for material mass spectroscopy, and neutron radiography (NR). A feasibility study on NR was done with MCNP simulation on collimator design and showed that calculated thermal flux level was high enough at the object position even though image size is very small, less than 4 cm diameter. Research activity has been done for sub-criticality measurement with modified neutron source multiplication method (MNSM). For sub-criticality evaluation with this method, three kinds of the neutron flux distributions such as forward, adjoint, fixed source neutron fluxes, which are solution in both eigenvalue and fixed source problems are needed. These flux distributions were calculated by using PARTISN code systems. Physics conditions are highly dependent on the source locations and rod positions as well as detector positions. Recent results showed that this method improved accuracy in rod worth

  4. [Interventions to improve the management of diabetes mellitus in primary health care and outpatient community settings].

    Science.gov (United States)

    Hansen, Lars Jørgen; Drivsholm, Thomas B

    2002-01-28

    This review should be cited as: Renders CM, Valk GD, Griffin S. Wagner EH, Eijk JThM van, Assendelft WJJ. Interventions to improve the management of diabetes mellitus in primary care, outpatient and community settings (Cochrane Review). In: The Cochrane Library, Issue 2, 2001. Oxford: Update Software. A substantive amendment to this systematic review was last made on 29 June 2000. Cochrane reviews are regularly checked and updated if necessary. Diabetes is a common chronic disease that is increasingly managed in primary care. Different systems have been proposed to manage diabetes care. To assess the effects of different interventions, targeted at health professionals or the structure in which they deliver care, on the management of patients with diabetes in primary care, outpatient and community settings. We searched the Cochrane Effective Practice and Organisation of Care Group specialised register, the Cochrane Controlled Trials Register (Issue 4 1999), MEDLINE (1966-1999), EMBASE (1980-1999), Cinahl (1982-1999), and reference lists of articles. Randomised trials (RCTs), controlled clinical trials (CCTs), controlled before and after studies (CBAs) and interrupted time series (ITS) analyses of professional, financial and organisational strategies aimed at improving care for people with Type 1 or Type 2 diabetes. The participants were health care professionals, including physicians, nurses and pharmacists. The outcomes included objectively measured health professional performance or patient outcomes, and self-report measures with known validity and reliability. Two reviewers independently extracted data and assessed study quality. Forty-one studies were included involving more than 200 practices and 48,000 patients. Twenty-seven studies were RCTs, 12 were CBAs, and two were ITS. The studies were heterogeneous in terms of interventions, participants, settings and outcomes. The methodological quality of the studies was often poor. In all studies the intervention

  5. Efficacy of fimasartan/hydrochlorothiazide combination in hypertensive patients inadequately controlled by fimasartan monotherapy

    Directory of Open Access Journals (Sweden)

    Rhee MY

    2015-06-01

    Full Text Available Moo-Yong Rhee,1 Sang Hong Baek,2 Weon Kim,3 Chang Gyu Park,4 Seung Woo Park,5 Byung-Hee Oh,6 Sang-Hyun Kim,7 Jae-Joong Kim,8 Joon-Han Shin,9 Byung-Su Yoo,10 Se-Joong Rim,11 Jong-Won Ha,12 Joon Hyung Doh,13 Youngkeun Ahn,14 Jei Keon Chae,15 Jeong Bae Park,16 Soon-Kil Kim,17 Cheol Ho Kim18 1Cardiovascular Center, Dongguk University Ilsan Hospital, Goyang, 2Catholic University of Korea, Seoul St Mary’s Hospital, Seoul, 3Cardiovascular Department of Internal Medicine, Kyung Hee University Medical Center, Seoul, 4Division of Cardiology, Guro Hospital, Korea University College of Medicine, Seoul, 5Division of Cardiology, Samsung Medical Center, Seoul, 6Department of Internal Medicine, Seoul National University Hospital, Seoul, 7Division of Cardiology, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, 8Division of Cardiology, Asan Medical Center, Seoul, 9Division of Cardiology, Ajou University Hospital, Suwon, 10Division of Cardiology, Wonju Severance Christian Hospital, Wonju, 11Division of Cardiology, GangNam Severance Hospital, Seoul, 12Division of Cardiology, Severance Hospital, Seoul, 13Division of Cardiology, Inje University Ilsan Hospital, Goyang, 14Department of Cardiology, Chonnam National University Hospital, Gwangju, 15Chonbuk National University Hospital, Jeonju, 16Department of Cardiology, Cheil General Hospital, Dankook University College of Medicine, Seoul, 17Department of Cardiology, Hanyang University Guri Hospital, Guri, 18Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea Background: The study reported here compared the blood pressure (BP-lowering efficacy of fimasartan alone with that of fimasartan/hydrochlorothiazide (HCTZ combination in patients whose BP goal was not achieved after 4 weeks of treatment with once-daily fimasartan 60 mg.Methods: Patients with sitting diastolic blood pressure (siDBP ≥90 mmHg with 4 weeks of once

  6. 三阴乳腺癌保乳治疗的疗效分析%Efficacy of conservative surgery on triple negative breast cancer

    Institute of Scientific and Technical Information of China (English)

    李永强; 苏逢锡

    2011-01-01

    Objective To compare the prognosis of triple negative and non-triple negative breast cancer after conservative surgery. Methods 593 patients with breast cancer were studied. All patients underwent conservative surgery therapy. All the patients' ER, PR, HER2/neu were available. The patients were classified as triple negative if all three markers were negative and non-triple negative if not. Ninty-two cases were classified as triple negative and 501 as non-triple negative. Results Till Nov. 2010, the median follow-up time of the 593 patients was 52 months. There was 11 in-breast relapses, 28 distant relapses, and 16 deaths. The triple negative cohort had a poorer distant metastasis-free rate compared with the non-triple negative cohort. But there was no significant difference in local control between the triple negative and the non-triple negative. Conclusions Triple-negative breast cancer has a more aggressive clinical course than non-triple negative breast cancer. However, there is no evidence that these patients are at higher risk for local relapse after conservative surgery therapy. Triple-negative breast cancer is still the candidate for conservative surgery therapy.%目的 探讨三阴乳腺癌行保乳治疗后的疗效观察.方法 行保乳手术治疗的乳腺癌患者593例,所有病例的ER、PR、HER2/neu状态均经病理证实,根据ER、PR、HER2/neu的状态分为三阴乳腺癌(ER、PR、HER2/neu 均为阴性)及非三阴乳腺癌(ER、PR、HEE2/neu其中任何一项为阳性)两组.其中三阴乳腺癌92例,非三阴乳腺癌501例.结果 截止2009年11月,共随访593例,中位随访时间为52月,出现局部复发病例11例,远处转移28例,死亡16例.三阴乳腺癌组比非三阴乳腺癌组有较高的远处转移率,预后较差.但三阴乳腺癌和非三阴乳腺癌患者在术后的局部复发率上无明显差异.结论 三阴乳腺癌相较非三阴乳腺癌总体预后差,但没有证据说明三阴乳腺癌行保乳手术后局

  7. Toxicity of Alkaloid-based Products from Tripterygium wilfordii on Non-target Organisms%雷公藤生物碱制品对非靶标生物的毒性研究

    Institute of Scientific and Technical Information of China (English)

    王李斌; 李婷; 何军; 冯俊涛; 马志卿; 张兴

    2012-01-01

    安全性评价是新农药开发及应用的重要基础.参照国家环保总局和农业部农药检定所制定的《化学农药环境安全评价试验准则》,测定了95%雷公藤总生物碱、1.0%雷公藤生物碱微乳剂、雷公藤乙醇浸膏和助剂系统对生态环境中非靶标生物的毒性.结果表明:95%雷公藤总生物碱对鹌鹑为高毒,对蜜蜂、家蚕为中毒,对鲤鱼、蚯蚓、蝌蚪均为低毒;1.0%雷公藤生物碱微乳剂对蝌蚪为高毒,对鹌鹑和家蚕为中毒,对鲤鱼、蜜蜂和蚯蚓均为低毒;雷公藤乙醇浸膏对鹌鹑为中毒,对蜜蜂、家蚕、鲤鱼、蚯蚓和蝌蚪均为低毒;助剂系统对供试生物均为低毒.由此可见,雷公藤生物碱制品对环境生物较为安全,但在桑园和水田附近慎用,并应注意对鸟类的保护.%Safety assessment is critically necessary for the development and application of new pesticides. Following the Experimental Guideline for Environmental Safety Evaluation of Chemical Pesticide, we evaluated the toxicity of 95% total alkaloid, 1.0% alkaloid ME , ethanol extract from Triperygiy wilfordii and the adjuvant on non-target organisms including quail( Cotumix chinensis), hee(Apis mellifera L.), silk-worm(Bombyx mori), fish( Cyprinus carpio), tadpole(Rana limnocharu )and earthwormt Eiseniafoelide). The results indicated that the toxicity of 95% total alkaloid is low on fish, earthworm and tadpole, moderate on bee and silkworm, and high on quail. The toxicity of 1.0% T. Wilfordii alkaloid ME is high on tadpole, moderately toxic on quail and silkworm, and low toxic on others. The toxicity of extract from T. Wilfordii is low on bee, silkworm, fish, earthworm and tadpole. And is moderately toxic on quail. The toxicity of adjuvant is low on all non-target organisms tested. We conclude that the alkaloid-based products from T. Wilfordii are generally safe to non-target animals; however, they should be applied cautiously in rice paddies and

  8. Comorbidities in obstructive lung disease in Korea: data from the fourth and fifth Korean National Health and Nutrition Examination Survey

    Directory of Open Access Journals (Sweden)

    Park HJ

    2015-08-01

    Full Text Available Hee Jin Park, Ah Young Leem, Sang Hoon Lee, Ju Han Song, Moo Suk Park, Young Sam Kim, Se Kyu Kim, Joon Chang, Kyung Soo Chung Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Severance Hospital, Institute of Chest Disease, Yonsei University College of Medicine, Seoul, South Korea Background: Comorbidities can occur frequently in patients with chronic obstructive pulmonary disease (COPD and can influence mortality and morbidity independently. It is increasingly recognized that many patients with COPD have comorbidities that have a major impact on their quality of life and survival. Therefore, we investigated the prevalence of comorbidities in Korean COPD populations. Methods: We used data obtained in the 6 years of the fourth and fifth Korean National Health and Nutrition Examination Survey (KNHANES IV and V. Among 50,405 subjects, 16,151 subjects aged ≥40 years who performed spirometry adequately were included in this study. Airway obstruction was defined as forced expiratory volume in 1 second/forced vital capacity <0.7, and the Global Initiative For Chronic Obstructive Lung Disease stage was used to evaluate the severity of airway obstruction. Statistical analyses were performed using SAS 9.2. Results: Among the 16,151 subjects (43.2% male, 56.8% female; mean age: 57.1 years for men and 57.2 years for women, 13.1% had obstructive lung function; 11.3%, restrictive lung function; and 75.6%, normal lung function. Among individuals with obstructive lung function, 45.3%, 49.4%, and 5.3% had mild, moderate, and severe and very severe airflow limitation. The prevalence of hypertension, diabetes mellitus (DM, underweight, and hypertriglyceridemia was higher in the obstructive lung function group than in the normal lung function group (49.6% vs 35.2%; 16.8% vs 10.5%; 3.3% vs 1.3%; 19.7% vs 17.0%. According to the severity of airway obstruction, hypertension and underweight were more common as severity increased

  9. Life Cycle Assessment of age-related environmental impact of biogenic hydraulic fluids; Life Cycle Assessment der alterungsbedingten Umweltvertraeglichkeit biogener Hydraulik-Schmierstoffe

    Energy Technology Data Exchange (ETDEWEB)

    Bressling, Jana

    2012-07-01

    Biogenic hydraulic fluids, based on synthetic esters (category: HEES), have an excellent environmental profile in the unused state, so that they are typically classified into water hazard class 1 or as ''not hazardous to water''. During storage at room temperature and tribological application, occurring chemical and toxicological changes take no account in the classification of lubricants until now. However, the ageing and oxidation stability gets increasing importance, since it determines the service life of lubricants in tribological systems in addition to the storage time. Since it always comes to direct and uncontrolled entries into the environment in case of accidents or hydraulic leaks, it is essential to assess whether there is an environmental hazard by waste oils. With an increased use of biogenic hydraulic fluids in environmentally sensitive areas, thus the need for an appropriate monitoring and assessment approach as part of a Life Cycle Assessment (LCA). The aquatic and miniaturised test procedures applied in this work with the Water Soluble Fraction (WSF) concept, allows a simple and quick screening of age-related ecotoxic potential of lubricants by oxidative processes and tribological application. For detection of genotoxic potential the umu-test is a suitable indicator test to detect geno- and cytotoxic effects by oxidative reactions. The determination of biodegradability is essential for the assessment of the environmental impact of hydraulic fluids. The optimised biodegradability test system ''O2/CO2-Headspace Test'' has proved itself as a suitable procedure for the investigation of biogenic lubricants within the scope of a LCA and shows therefore a comparable method of the required test procedures for the assignment of ecolabels. In addition, the combination of biological test procedures and chemical analysis allows a comprehensive investigation of effects and causes of age-related changes of hydraulic

  10. A statistical study of the maxillofacial diseases by radiograms

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Yoo Tai; Lee, Sang Chull [College of Dentistry, Kyunghee University, Seoul (Korea, Republic of)

    1974-11-15

    This report based on 300 cases of serious diseases in maxillofacial region by radiograms seen at the department of dental radiodontics, infirmary school of dentistry, Kyung Hee University from October 1971 to August 1974. The maxillofacial diseases were analysed upon the following items, such as 1) the frequency of dominant diseases, 2) sex-ratio of male to female, 3) predominant region of diseases, 4) comparison with the age, 5) the incidence of diseases in relative to the individual teeth. The results were obtained as follows. 1) Among the total of 300 cases of the patients, the frequency of dominant diseases of patients were fractures of facial bone (44.3 {+-} 2.87%), inflammatory diseases (22.7 {+-} 2.39%), cysts (11.1 {+-} 1.62%), tumors(10.7 {+-} 1.77%), maxillary sinusitis (7.9 {+-} 1.56%), temporomandibular joint disorders(3.3 {+-} 1.05%) in the order. 2) The sex ratio of male to female in occurrence of jaw fractures were 7.3 : 1, temporomandibular joint disorders were 2.1 : 1, inflammatory diseases were 1.8:1, maxillary sinusitis were 1.7 : 1, but tumors were 1: 1, while cysts were 1:1 .2 in sex difference.3) The predominant region of mandibular fractures were symphysis (17.3 {+-} 3.27%), canine region (15.0 {+-} 3.09%), and angle region(14.3 {+-} 3.04%) in the order. Inflammatory diseases were occurred frequently in mandible and it's left side were a little dominant. Odontogenic cysts were observed frequently in maxilla, but regardless of right and left. Carcinomas were involved most frequently in maxilla, while sarcomas and ameloblastomas in mandible. Frequency of the maxillary sinusitis w ere dominant in right side and molar area, also temporomandibular joint disorders were dominant in right side. 4) To study comparing with the age, jaw fractures showed the highest ratio at the 2nd decade (32.3 {+-} 4.06%), and 3rd decade (27.8 {+-} 3.89%), 4th decade (19.6 {+-} 3.44%), 6th decade (9.0 {+-} 2.47%), 5th decade(6.0 {+-} 2.06%), lst decade(5.3 {+-} 1

  11. Rapid green synthesis of silver and gold nanoparticles using Dendropanax morbifera leaf extract and their anticancer activities

    Directory of Open Access Journals (Sweden)

    Wang C

    2016-08-01

    Full Text Available Chao Wang,1 Ramya Mathiyalagan,2 Yeon Ju Kim,1 Veronica Castro-Aceituno,1 Priyanka Singh,1 Sungeun Ahn,1 Dandan Wang,1 Deok Chun Yang1,2 1Department of Oriental Medicine Biotechnology and Ginseng Bank, 2Graduate School of Biotechnology and Ginseng Bank, College of Life Sciences, Kyung Hee University, Yongin, Republic of Korea Abstract: Dendropanax morbifera Léveille is an oriental medicinal plant that is traditionally used in folk medicine and grows in a specific region of South Korea. We aimed to enhance the utilization of D. morbifera medicinal plants for synthesis of silver nanoparticles (AgNPs and gold nanoparticles (AuNPs. D. morbifera leaf extract acted as both a reducing and a stabilizing agent that rapidly synthesized Dendropanax AgNPs (D-AgNPs and Dendropanax AuNPs (D-AuNPs. The D-AgNPs and D-AuNPs were characterized by ultraviolet-visible spectroscopy, energy dispersive X-ray analysis, elemental mapping, field emission transmission electron microscopy, X-ray diffraction, and dynamic light scattering. The characterizations revealed that the D-AgNPs and D-AuNPs were in polygon and hexagon shapes with average sizes of 100–150 nm and 10–20 nm, respectively. The important outcomes were the synthesis of AgNPs and AuNPs within 1 hour and 3 minutes, respectively, avoiding the subsequent processing for removal of any toxic components or for stabilizing the nanoparticles. Additionally, D-AgNPs and D-AuNPs were examined for cytotoxicity in a human keratinocyte cell line and in A549 human lung cancer cell line. The results indicated that D-AgNPs exhibited less cytotoxicity in the human keratinocyte cell line at 100 µg/mL after 48 hours. On the other hand, D-AgNPs showed potent cytotoxicity in the lung cancer cells at the same concentration after 48 hours, whereas D-AuNPs did not exhibit cytotoxicity in both cell lines at the same concentration. However, both D-AgNPs and D-AuNPs at 50 µg/mL enhanced the cytotoxicity of ginsenoside

  12. Pharmacokinetic comparison of sustained- and immediate-release formulations of cilostazol after multiple oral doses in fed healthy male Korean volunteers

    Directory of Open Access Journals (Sweden)

    Kim YH

    2015-07-01

    Full Text Available Yo Han Kim,1 Jong-Lyul Ghim,2 Jin Ah Jung,2 Sang-Heon Cho,3 Sangmin Choe,4 Hee Youn Choi,1 Kyun-Seop Bae,1 Hyeong-Seok Lim1 1Department of Clinical Pharmacology and Therapeutics, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, 2Department of Clinical Pharmacology, Inje University, Busan Paik Hospital, Busan, 3Department of Clinical Pharmacology, Inha University Hospital, Inha University School of Medicine, Incheon, 4Clinical Trials Center, Pusan National University Hospital, Busan, Republic of Korea Background: A new extended-release form of cilostazol has recently been developed. This study was conducted to compare the pharmacokinetic characteristics of sustained-release (SR and immediate-release (IR formulations of cilostazol after multiple oral doses in healthy male Korean volunteers.Methods: This was an open-label, randomized, multiple-dose, crossover study conducted in 30 healthy Korean subjects. In each treatment period, subjects received oral doses of 200 mg SR formulation every 24 hours or 100 mg IR formulation every 12 hours for 5 consecutive days in a fed state, with a washout period of 9 days. The plasma concentrations of cilostazol and its metabolites were determined using a validated liquid chromatography-tandem mass spectrometry method. The area under the plasma concentration–time curve within a dosing interval (AUCT, the measured peak plasma concentration at steady state (Cmax,ss, and the time to reach Cmax,ss (tmax,ss were analyzed using a noncompartmental method. Results: A total of 24 healthy male subjects completed the study. The mean (standard deviation [SD] AUCT (96–120 hours values for SR and IR were 27,378.0 (10,301.6 ng·h/mL and 27,860.3 (7,152.3 ng·h/mL, respectively. The mean (SD Cmax,ss values were 2,741.4 (836.0 ng/mL and 2,051.0 (433.2 ng/mL, respectively. The median tmax,ss values were 8.0 hours and 4.0 hours, respectively. The geometric mean ratios (90% confidence intervals of

  13. Relative bioavailability of levodropropizine 60 mg capsule and syrup formulations in healthy male Korean volunteers: a singledose, randomized-sequence, open-label, two-way crossover study.

    Science.gov (United States)

    Jang, Jae-Won; Seo, Ji-Hyung; Jo, Min-Ho; Lee, Young-Joo; Cho, Young-Wuk; Yim, Sung-Vin; Lee, Kyung-Tae

    2013-02-01

    Levodropropizine is an oral non-opioid anti-tussive drug used in treatment of cough. A new generic 60 mg capsule formulation of levodropropizine has recently been developed. The aim of this study was to assess the pharmacokinetics and bioequivalence of the test (capsule) formulation and reference (syrup) formulation of levodropropizine (60 mg) in healthy, fasted, male Korean volunteers. This was a single-dose, randomized sequence, open-label, 2-period crossover study conducted in healthy male Korean volunteers in the fasted state at Kyung Hee University Medical Center (Seoul, Republic of Korea). A single oral dose of the test or reference formulation was followed by a 1-week washout period, after which subjects received the alternative formulation. Blood samples were collected at 0 (predose), 0.17, 0.33, 0.5, 0.75, 1, 1.5, 2, 3, 4, 6, 8, and 12 hours after study drug administration. Plasma concentration of levodropropizine was determined using a validated liquid chromatography tandem mass spectrometry (LCMS/ MS) method. The formulations were considered bioequivalent if the 90% CIs for C(max), AUC(0-12h) and AUC(0-∞) were within the predetermined bioequivalence range (80 - 125%, according to the guidelines of the Korea Food and Drug Administration (Korea FDA)). Tolerability was evaluated throughout the study based on vital sign measurements, laboratory analysis (blood biochemistry, hematology, hepatic function and urinalysis) and subject interviews concerning adverse events (AEs). A total of 36 male Korean subjects (mean (SD) age, 23.9 (2.4) years (range 19 - 30 years); height, 176.2 (6.1) cm (range 161 - 190 cm); weight, 69.8 (9.1) kg (range 54.0 - 92.2 kg); body mass index, 22.4 (2.1) kg/m2 (range 19.1 - 28.3 kg/m2)) was enrolled and completed the study. The mean values for C(max), t(max), AUC(0-12h), and AUC(0-∞) with the test formulation of levodropropizine were 331.51 ng/ml, 0.60 hours, 784.32 ng×h/ml, and 825.82 ng×h/ml, respectively; for the reference

  14. Optical imaging of absorption and distribution of RITC-SiO2 nanoparticles after oral administration

    Directory of Open Access Journals (Sweden)

    Lee CM

    2014-12-01

    Full Text Available Chang-Moon Lee,1 Tai Kyoung Lee,2–5 Dae-Ik Kim,1,6 Yu-Ri Kim,7 Meyoung-Kon Kim,7 Hwan-Jeong Jeong,2–5 Myung-Hee Sohn,2–5 Seok Tae Lim2–5 1Department of Biomedical Engineering, Chonnam National University, Yeosu, Jeollanam-Do, Republic of Korea; 2Department of Nuclear Medicine, Chonbuk National University Medical School and Hospital, Jeonju, Jeollabuk-Do, Republic of Korea; 3Cyclotron Research Center, Chonbuk National University Medical School and Hospital, Jeonju, Jeollabuk-Do, Republic of Korea; 4Biomedical Research Institute, Chonbuk National University Medical School and Hospital, Jeonju, Jeollabuk-Do, Republic of Korea; 5Molecular Imaging and Therapeutic Medicine Research Center, Chonbuk National University Medical School and Hospital, Jeonju, Jeollabuk-Do, Republic of Korea; 6School of Electrical, Electronic Communication, and Computer Engineering, Chonnam National University, Yeosu, Jeollanam-Do, Republic of Korea; 7Department of Biochemistry and Molecular Biology, Korea University Medical School and College, Seounbuk-Gu, Seoul, Republic of Korea Purpose: In this study, we investigated the absorption and distribution of rhodamine B isothiocyanate (RITC-incorporated silica oxide nanoparticles(SiNPs (RITC-SiNPs after oral exposure, by conducting optical imaging, with a focus on tracking the movement of RITC-SiNPs of different particle size and surface charge. Methods: RITC-SiNPs (20 or 100 nm; positively or negatively charged were used to avoid the dissociation of a fluorescent dye from nanoparticles via spontaneous or enzyme-catalyzed reactions in vivo. The changes in the nanoparticle sizes and shapes were investigated in an HCl solution for 6 hours. RITC-SiNPs were orally administered to healthy nude mice at a dose of 100 mg/kg. Optical imaging studies were performed at 2, 4, and 6 hours after oral administration. The mice were sacrificed at 2, 4, 6, and 10 hours post-administration, and ex vivo imaging studies were performed

  15. The fate of calcium carbonate nanoparticles administered by oral route: absorption and their interaction with biological matrices

    Directory of Open Access Journals (Sweden)

    Lee JA

    2015-03-01

    Full Text Available Jeong-A Lee,1,* Mi-Kyung Kim,1,* Hyoung-Mi Kim,2,* Jong Kwon Lee,3 Jayoung Jeong,4 Young-Rok Kim,5 Jae-Min Oh,2 Soo-Jin Choi1 1Department of Food Science and Technology, Seoul Women’s University, Seoul, Republic of Korea; 2Department of Chemistry and Medical Chemistry, College of Science and Technology, Yonsei University, Wonju, Republic of Korea; 3Hazard Substances Analysis Division, Gwangju Regional Food and Drug Administration, Ministry of Food and Drug Safety, Gwangju, Republic of Korea; 4Toxicological Research Division, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Chungcheongbuk-do, Republic of Korea; 5Department of Food Science and Biotechnology, Kyung Hee University, Yongin, Republic of Korea *These authors contributed equally to this work Background: Orally administered particles rapidly interact with biological fluids containing proteins, enzymes, electrolytes, and other biomolecules to eventually form particles covered by a corona, and this corona potentially affects particle uptake, fate, absorption, distribution, and elimination in vivo. This study explored relationships between the biological interactions of calcium carbonate particles and their biokinetics.Methods: We examined the effects of food grade calcium carbonates of different particle size (nano [N-Cal] and bulk [B-Cal]: specific surface areas of 15.8 and 0.83 m2/g, respectively on biological interactions in in vitro simulated physiological fluids, ex vivo biofluids, and in vivo in gastrointestinal fluid. Moreover, absorption and tissue distribution of calcium carbonates were evaluated following a single dose oral administration to rats.Results: N-Cal interacted more with biomatrices than bulk materials in vitro and ex vivo, as evidenced by high fluorescence quenching ratios, but it did not interact more actively with biomatrices in vivo. Analysis of coronas revealed that immunoglobulin, apolipoprotein, thrombin, and fibrinogen

  16. Is carotid artery evaluation necessary for primary prevention in asymptomatic high-risk patients without atherosclerotic cardiovascular disease?

    Directory of Open Access Journals (Sweden)

    Kim GH

    2015-07-01

    Full Text Available GeeHee Kim,1 Ho-Joong Youn,2 Yun-Seok Choi,2 Hae Ok Jung,2 Wook Sung Chung,2 Chul-Min Kim1 1Department of Internal Medicine, St Vincent’s Hospital, The Catholic University of Korea, Suwon, 2Division of Cardiology, Department of Internal Medicine, School of Medicine, The Catholic University of Korea, Seoul, Republic of Korea Objective: Routine measurement of the carotid intima–media thickness is not recommended in recent clinical practice guidelines for risk assessment of the first atherosclerotic cardiovascular disease (ASCVD event (the definition of which includes acute coronary syndromes, a history of myocardial infarction, stable or unstable angina, coronary or other arterial revascularization, stroke, transient ischemic attack, or peripheral arterial disease presumed to be of atherosclerotic origin. The aim of the present study was to elucidate the role of carotid artery evaluation for primary prevention of ASCVD in asymptomatic high-risk patients visiting a teaching hospital.Methods: Eight hundred seventy-three patients (487 male [55.8%], mean age 59.4±11.5 years who were statin-naive and without ASCVD, which was proven by coronary angiography or coronary CT angiography, were enrolled in this study. The patients underwent carotid scanning in the Medical Department of St Mary’s Hospital from September 2003 to March 2009. ASCVD outcomes were evaluated for median follow-up of 1,402 days.Results: A total of 119 participants experienced ASCVD events. In multivariate Cox regression analysis, age (hazard ratio [HR] =1.026, 95% confidence interval [CI] =1.002–1.050, P=0.033, history of smoking (HR =1.751, 95% CI =1.089–2.815, P=0.021, statin therapy (HR =0.388, 95% CI =0.205–0.734, P=0.004, and carotid plaques (HR =1.556, 95% CI =1.009–2.400, P=0.045 were associated with ASCVD events. In middle-aged group (45≤ age <65, n=473, history of smoking (HR =1.995, 95% CI =1.142–3.485, P=0.015, statin therapy (HR =0.320, 95% CI =0.131

  17. Korean Medication Algorithm for Bipolar Disorder 2014: comparisons with other treatment guidelines

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    Jeong JH

    2015-06-01

    Full Text Available Jong-Hyun Jeong,1 Jeong Goo Lee,2,3 Moon-Doo Kim,4 Inki Sohn,5 Se-Hoon Shim,6 Hee Ryung Wang,1 Young Sup Woo,1 Duk-In Jon,7 Jeong Seok Seo,8 Young-Chul Shin,9 Kyung Joon Min,10 Bo-Hyun Yoon,11 Won-Myong Bahk1 1Department of Psychiatry, College of Medicine, The Catholic University of Korea, Seoul, 2Department of Psychiatry, Haeundae Paik Hospital, College of Medicine, Paik Institute for Clinical Research, Inje University, 3Department of Health Science and Technology, Graduate School of Inje University, Busan, 4Department of Psychiatry, Jeju National University Hospital, Jeju, 5Department of Psychiatry, Keyo Hospital, Keyo Medical Foundation, Uiwang, 6Department of Psychiatry, Soonchunhyang University Cheonan Hospital, College of Medicine, Soonchunhyang University, Cheonan, 7Department of Psychiatry, Sacred Heart Hospital, College of Medicine, Hallym University, Anyang, 8Department of Psychiatry, Konkuk University Chungju Hospital, School of Medicine, Konkuk University, Chungju, 9Department of Psychiatry, Kangbuk Samsung Hospital, School of Medicine, Sungkyunkwan University, Seoul, 10Department of Psychiatry, Chung-Ang University Hospital, College of Medicine, Chung-Ang University, Seoul, 11Department of Psychiatry, Naju National Hospital, Naju, Korea Abstract: Our goal was to compare the recommendations of the Korean Medication Algorithm Project for Bipolar Disorder 2014 (KMAP-BP 2014 with other recently published guidelines for the treatment of bipolar disorder. We reviewed a total of four recently published global treatment guidelines and compared each treatment recommendation of the KMAP-BP 2014 with those in other guidelines. For the initial treatment of mania, there were no significant differences across treatment guidelines. All recommended mood stabilizer (MS or atypical antipsychotic (AAP monotherapy or the combination of an MS with an AAP as a first-line treatment strategy for mania. However, the KMAP-BP 2014 did not prefer monotherapy

  18. Quantum Field Theory in Curved Spacetime

    Science.gov (United States)

    Reynolds, Sally C.; Gallagher, Andrew

    2012-03-01

    List of contributors; Foreword J. T. Francis Thackeray; 1. African genesis: an evolving paradigm Sally C. Reynolds; 2. Academic genealogy Peter Ungar and Phillip V. Tobias; Part I. In Search of Origins: Evolutionary Theory, New Species, and Paths into the Past: 3. Speciation in hominin evolution Colin Groves; 4. Searching for a new paradigm for hominid origins in Chad (Central Africa) Michel Brunet; 5. From hominoid arboreality to hominid bipedalism Brigitte Senut; 6. Orrorin and the African ape/hominid dichotomy Martin Pickford; 7. A brief history and results of 40 years of Sterkfontein excavations Ronald J. Clarke; Part II. Hominin Morphology Through Time: Brains, Bodies and Teeth: 8. Hominin brain evolution, 1925-2011: an emerging overview Dean Falk; 9. The issue of brain reorganisation in Australopithecus and early hominids: Dart had it right Ralph L. Holloway; 10. The mass of the human brain: is it a spandrel? Paul R. Manger, Jason Hemingway, Muhammad Spocter and Andrew Gallagher; 11. Origin and diversity of early hominin bipedalism Henry M. McHenry; 12. Forelimb adaptations in Australopithecus afarensis Michelle S. M. Drapeau; 13. Hominin proximal femur morphology from the Tugen Hills to Flores Brian G. Richmond and William L. Jungers; 14. Daily rates of dentine formation and root extension rates in Paranthropus boisei, KNM-ER 1817, from Koobi Fora, Kenya M. Christopher Dean; 15. On the evolutionary development of early hominid molar teeth and the Gondolin Paranthropus molar Kevin L. Kuykendall; 16. Digital South African fossils: morphological studies using reference-based reconstruction and electronic preparation Gerhard W. Weber, Philipp Gunz, Simon Neubauer, Philipp Mitteroecker and Fred L. Bookstein; Part III. Modern Human Origins: Patterns, and Processes: 17. Body size in African Middle Pleistocene Homo Steven E. Churchill, Lee R. Berger, Adam Hartstone-Rose and Headman Zondo; 18. The African origin of recent humanity Milford H. Wolpoff and Sang-Hee Lee

  19. 韩日岛争与美国的态度%Island Dispute between Japan and South Korea as well as the U.S. Attitude

    Institute of Scientific and Technical Information of China (English)

    李相旼[韩

    2013-01-01

    直到19世纪70年代,日本官方在各种文件中仍承认独岛为韩国的领土。20世纪初,日本军国主义在发动大规模侵略战争期间强行将独岛划归日本所有(日本称“竹岛”)。二战结束后,朴正熙执政期间,由日方提出的独岛归属问题成为韩日双方争论的焦点。整个冷战期间,由于韩日两国都是美国的重要盟国,每当韩日两国出现岛争问题时,美国表面上总是持中立态度,实际上存在着听信日本一面之词而混淆是非的问题。韩日岛争的问题不只是领土归属问题,也是一个是历史认识问题。同时,韩日岛争不仅是韩日两国间的问题,也应该加上美国因素,在东北亚国际关系的框架下考察这一历史遗留问题才是恰当的。美国作为调解者,理应选择历史上独岛主权归属韩国的立场,客观公正地解决韩日两国之间的岛争。%Japan had admitted that Dokdo belonged to Korea in various ocial documents until the 1870s. How-ever, in the early 20th century, Japanese militarism forcibly placed Dokdo into Japanese territory as“Takeshima”in a large-scale war of aggression. After World War II, under the government of Park Chung-hee, the ownership of Dokdo became a focus of debate between Korea and Japan. Throughout the Cold War, the United States kept a neutral stand seemingly whenever the island dispute appeared between South Korea and Japan, as the two of them were important U.S. allies by then; while in fact, it believed what Japan said one-sidedly that confused right and wrong. The island dispute between South Korea and Japan was not simply a territorial attribution but the understanding of history. Meanwhile, the island dispute was not simply the problem between South Korea and Japan, the U.S. should be taken into account; and it is proper only when the historical issue is taken into account under the framework of international relations in Northeast Asia

  20. Association of polymorphisms in FADS gene with age-related changes in serum phospholipid polyunsaturated fatty acids and oxidative stress markers in middle-aged nonobese men

    Directory of Open Access Journals (Sweden)

    Hong SH

    2013-05-01

    Full Text Available Seul Hee Hong,1,* Jung Hyun Kwak,2,* Jean Kyung Paik,3 Jey Sook Chae,2 Jong Ho Lee1,21National Research Laboratory for Clinical Nutrigenetics/Nutrigenomics, 2Research Institute of Science for Aging, Yonsei University, Seoul, South Korea; 3Department of Food and Nutrition, Eulji University, Gyeonggi-do, South Korea *These authors contributed equally to this workBackground: To investigate the association of FADS gene polymorphisms with age-related changes in polyunsaturated fatty acids (PUFAs in serum phospholipids and oxidative stress markers.Methods: We genotyped 122 nonobese men aged 35–59 years without any known diseases at baseline for rs174537 near FADS1 (FEN1 rs174537G > T, FADS2 (rs174575, rs2727270, and FADS3 (rs1000778, and followed them for 3 years.Results: Among the four single-nucleotide polymorphisms, the minor variants of rs174537 and rs2727270 were significantly associated with lower concentrations of long-chain PUFAs. However, rs174537G > T showed stronger association. At baseline, men with the rs174537T allele had lower arachidonic acid (AA and AA/linoleic acid (LA, and higher interleukin (IL-6 levels than rs174537GG counterparts. After 3 years, rs174537GG men had significantly increased AA (P = 0.022, AA/dihomo-γ-linolenic acid (DGLA (P = 0.007, docosapentaenoic acid (DPA, low-density lipoprotein (LDL cholesterol, and oxidized LDL (ox-LDL, but decreased eicosatrienoic acid. The rs174537T group showed significantly increased γ-linolenic acid and ox-LDL, and decreased eicosadienoic acid, eicosapentaenoic acid (EPA/α-linolenic acid (ALA, and IL-6. After 3 years, the rs174537T group had lower AA (P < 0.001, AA/DGLA (P = 0.019, EPA, DPA, EPA/ALA, and urinary 8-epi-prostaglandin F2α (8-epi-PGF2α (P = 0.011 than rs174537GG. Changes in AA (P = 0.001, AA/DGLA (P = 0.017, EPA, DPA, EPA/ALA, and urinary 8-epi-PGF2α (P < 0.001 were significantly different between the groups after adjusting for baseline values. Overall, changes in AA

  1. Study on MRI Changes in Phenylketonuria in Patients Referred to Mofid Hospital/Iran

    Directory of Open Access Journals (Sweden)

    Parveneh KARIMZADEH

    2014-04-01

    was seen between phenylalanine level (at the time of Imaging and MRI score. But there was a relationship between mean 1 year phenylalanine level and MRI score.ConclusionAccording to the results of this study, brain MRI and white matter involvement can be used for evaluation of long-term control of phenylalanine level in PKU cases. References1. Blau Nenad. Phenylketonuria and BH4 Deficiencies. London: UNI-MED; 2010.2. Buck PS. The child who never grew. Woodbine House; 1992.3. Rezvani I, Melvin JJ. Defects in metabolism of amino acids. In: Kliegman RM, Stanton BF, St. Geme J, Behrman RE, editors. Nelson Textbook of Pediatrics. 19th ed. USA: Elsevier; 2011. p. 418-22.4. Menkes J, Wilcox WR. Inherited Metabolic Diseases of nervous system. In: Menkes JH, editor Child neurology. 7th ed. Philadelphia: Lippincott Williams&Wilkins; 2006. p. 34-36.5. Aicardi J. Diseases of the nervous system in childhood. London: Mac Keith press; 2009.6. Enns GM, Cowan TM, Klein O, Packman S. Aminoacidemias and organic acidemias. In: Swaiman KF. Swaimans Pediatric Neurology principle and practice. 5th ed. China: Saunders; 2012. p. 330-7.7. Barkovich J. Toxic and Metabolic Brain disorders. In: Barkovich J, editor Pediatric Neuroimaging. 4th ed. USA: Lippincott William&Wilkins;2005. p. 88-92.8. Van der knaap MS. Phenylketonuria. In: Van der knaap MS, Valk J, editor. Magnetic resonance of Myelination and Myelin Disorders. 3rd ed. Germany: Springer; 2005. p. 285-90.9. Manara R, Burlina AP, Citton V, Ermani M, Vespignani F, Carollo C, et al. Brain MRI diffusion-Weighted imaging in patients with classical phenylketonuria: Neuroradiology (200951:803-12.10. Möller HE, Weglage J, Bick U, Wiedermann D, Feldmann R, Ullrich K. Brain imaging and proton Magnetic Resonance Spectroscopy in Patients with Phenylketonuria Pediatrics 2003;112(6 Pt 2:1580-3.11. Phillips MD, McGraw P, Lowe MJ, Mathews VP, Hainline BE. Diffusion-Weighted Imaging of White Matter Abnormalities in Patients with Phenylketonuria

  2. EDITORIAL: Focus on Plasma Medicine

    Science.gov (United States)

    Morfill, G. E.; Kong, M. G.; Zimmermann, J. L.

    2009-11-01

    -pressure microwave plasmas in an N2 and O2 gas mixture M K Singh, A Ogino and M Nagatsu Degradation of adhesion molecules of G361 melanoma cells by a non-thermal atmospheric pressure microplasma H J Lee, C H Shon, Y S Kim, S Kim, G C Kim and M G Kong The acidification of lipid film surfaces by non-thermal DBD at atmospheric pressure in air A Helmke, D Hoffmeister, N Mertens, S Emmert, J Schuette and W Vioel Reduction and degradation of amyloid aggregates by a pulsed radio-frequency cold atmospheric plasma jet D L Bayliss, J L Walsh, G Shama, F Iza and M G Kong The effect of low-temperature plasma on bacteria as observed by repeated AFM imaging René Pompl, Ferdinand Jamitzky, Tetsuji Shimizu, Bernd Steffes, Wolfram Bunk, Hans-Ulrich Schmidt, Matthias Georgi, Katrin Ramrath, Wilhelm Stolz, Robert W Stark, Takuya Urayama, Shuitsu Fujii and Gregor Eugen Morfill Removal and sterilization of biofilms and planktonic bacteria by microwave-induced argon plasma at atmospheric pressure Mi Hee Lee, Bong Joo Park, Soo Chang Jin, Dohyun Kim, Inho Han, Jungsung Kim, Soon O Hyun, Kie-Hyung Chung and Jong-Chul Park Cell permeabilization using a non-thermal plasma M Leduc, D Guay, R L Leask and S Coulombe Physical and biological mechanisms of direct plasma interaction with living tissue Danil Dobrynin, Gregory Fridman, Gary Friedman and Alexander Fridman Nosocomial infections-a new approach towards preventive medicine using plasmas G E Morfill, T Shimizu, B Steffes and H-U Schmidt Generation and transport mechanisms of chemical species by a post-discharge flow for inactivation of bacteria Takehiko Sato, Shiroh Ochiai and Takuya Urayama Low pressure plasma discharges for the sterilization and decontamination of surfaces F Rossi, O Kylián, H Rauscher, M Hasiwa and D Gilliland Contribution of a portable air plasma torch to rapid blood coagulation as a method of preventing bleeding S P Kuo, O Tarasenko, J Chang, S Popovic, C Y Chen, H W Fan, A Scott, M Lahiani, P Alusta, J D Drake and M Nikolic A two

  3. EDITORIAL: Invited papers from ISAMMA 2010 (Sendai, Japan, 12-16 July 2010) Invited papers from ISAMMA 2010 (Sendai, Japan, 12-16 July 2010)

    Science.gov (United States)

    Takahashi, M.; Saito, H.

    2011-02-01

    overseas. The programme involved 4 plenary talks, 37 invited talks, 85 contributed talks and 352 posters. All submitted papers were reviewed in order to meet the standards of Journal of Physics D: Applied Physics and Journal of Physics: Conference Series. We are grateful to all participants for their valuable contributions and active discussions. We gratefully acknowledge the financial support of 17 Japanese companies and 7 Japanese foundations. Invited papers from ISAMMA 2010 Contents Current status and recent topics of rare-earth permanent magnets S Sugimoto Alloying effect on the magnetic properties of RFeB-type bulk magnets H W Chang, C C Hsieh, J Y Gan, Y T Cheng, M F Shih and W C Chang Coercivity distributions in Nd-Fe-B sintered magnets produced by the grain boundary diffusion process H Nakamura, K Hirota, T Ohashi and T Minowa Recent progress in high Bs Fe-based nanocrystalline soft magnetic alloys M Ohta and Y Yoshizawa Electric-field effects on magnetic anisotropy in Pd/Fe/Pd(0 0 1) surface Shinya Haraguchi, Masahito Tsujikawa, Junpei Gotou and Tatsuki Oda Gate modulation of spin precession in a semiconductor channel Hyun Cheol Koo, Jae Hyun Kwon, Jonghwa Eom, Joonyeon Chang, Suk Hee Han and Mark Johnson Ferromagnetic resonance of epitaxial Fe nanodots grown on MgO measured using coplanar waveguides M Mizuguchi and K Takanashi Switching phase diagrams of current-induced magnetization switching in asymmetric MgO-based magnetic tunnel junctions Seung-Young Park, Jae-Ho Han, Se-Chung Oh, Jang-Eun Lee, Kyung-Tae Nam, Hyun-Woo Lee, Younghun Jo and Kyung-Jin Lee Temperature dependence of spin-dependent transport properties of Co2MnSi-based current-perpendicular-to-plane magnetoresistive devices Y Sakuraba, K Izumi, S Bosu, K Saito and K Takanashi Adsorbate-induced spin-polarization enhancement of Fe3O4(0 0 1) A Pratt, M Kurahashi, X Sun and Y Yamauchi Antiferromagnetic coupling between spinel ferrite and α-Fe layers in Fe3-δO4/MgO/Fe(0 0 1) epitaxial films Hideto

  4. EDITORIAL: Flexible OLEDs and organic electronics Flexible OLEDs and organic electronics

    Science.gov (United States)

    Kim, Jang-Joo; Han, Min-Koo; Noh, Yong-Young

    2011-03-01

    -voltage, solution-processed organic field-effect transistors M Caironi, Y-Y Noh and H Sirringhaus Nonvolatile memory thin-film transistors using an organic ferroelectric gate insulator and an oxide semiconducting channel Sung-Min Yoon, Shinhyuk Yang, Chun-Won Byun, Soon-Won Jung, Min-Ki Ryu, Sang-Hee Ko Park, ByeongHoon Kim, Himchan Oh, Chi-Sun Hwang and Byoung-Gon Yu The status and perspectives of metal oxide thin-film transistors for active matrix flexible displays Jae Kyeong Jeong Vertical phase segregation of hybrid poly(3-hexylthiophene) and fullerene derivative composites controlled via velocity of solvent drying Tao Song, Zhongwei Wu, Yingfen Tu, Yizheng Jin and Baoquan Sun Variations of cell performance in ITO-free organic solar cells with increasing cell areas Jun-Seok Yeo, Jin-Mun Yun, Seok-Soon Kim, Dong-Yu Kim, Junkyung Kim and Seok-In Na

  5. Tidal Energy System for On-Shore Power Generation

    Energy Technology Data Exchange (ETDEWEB)

    Bruce, Allan J

    2012-06-26

    Addressing the urgent need to develop LCOE competitive renewable energy solutions for US energy security and to replace fossil-fuel generation with the associated benefits to environment impacts including a reduction in CO2 emissions, this Project focused on the advantages of using hydraulic energy transfer (HET) in large-scale Marine Hydrokinetic (MHK) systems for harvesting off-shore tidal energy in US waters. A recent DOE resource assessment, identifies water power resources have a potential to meet 15% of the US electric supply by 2030, with MHK technologies being a major component. The work covered a TRL-4 laboratory proof-in-concept demonstration plus modeling of a 15MW full scale system based on an approach patented by NASA-JPL, in which submerged high-ratio gearboxes and electrical generators in conventional MHK turbine systems are replaced by a submerged hydraulic radial pump coupled to on-shore hydraulic motors driving a generator. The advantages are; first, the mean-time-between-failure (MTBF), or maintenance, can be extended from approximately 1 to 5 years and second, the range of tidal flow speeds which can be efficiently harvested can be extended beyond that of a conventional submerged generator. The approach uses scalable, commercial-off-the-shelf (COTS) components, facilitating scale-up and commercialization. All the objectives of the Project have been successfully met (1) A TRL4 system was designed, constructed and tested. It simulates a tidal energy turbine, with a 2-m diameter blade in up to a 2.9 m/sec flow. The system consists of a drive motor assembly providing appropriate torque and RPM, attached to a radial piston pump. The pump circulates pressurized, environmentally-friendly, HEES hydraulic fluid in a closed loop to an axial piston motor which drives an electrical generator, with a resistive load. The performance of the components, subsystems and system were evaluated during simulated tidal cycles. The pump is contained in a tank for

  6. Efficacy and safety of two fixed-dose combinations of S-amlodipine and telmisartan (CKD-828 versus S-amlodipine monotherapy in patients with hypertension inadequately controlled using S-amlodipine monotherapy: an 8-week, multicenter, randomized, double-blind, Phase III clinical study

    Directory of Open Access Journals (Sweden)

    Ihm SH

    2016-11-01

    Full Text Available Sang-Hyun Ihm,1 Hui-Kyung Jeon,1 Tae-Joon Cha,2 Taek-Jong Hong,3 Sang-Hyun Kim,4 Nae-Hee Lee,5 Jung Han Yoon,6 Namsik Yoon,7 Kyung-Kuk Hwang,8 Sang-Ho Jo,9 Ho-Joong Youn1 1Division of Cardiology, Department of Internal Medicine, The Catholic University of Korea, Seoul, 2Division of Cardiology, Department of Internal Medicine, Kosin University College of Medicine, 3Division of Cardiology, Department of Internal Medicine, Pusan National University Hospital, Busan, 4Division of Cardiology, Department of Internal Medicine, Boramae Medical Center, Seoul National University College of Medicine, Seoul, 5Department of Cardiology, Soonchunhyang University Hospital, Bucheon, 6Division of Cardiology, Wonju College of Medicine, Yonsei University, Wonju, 7Department of Cardiology, Chonnam National University Hospital, Gwangju, 8Department of Internal Medicine, Chungbuk National University, College of Medicine, Cheongju, 9Division of Cardiology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, South Korea Purpose: To evaluate the blood pressure (BP lowering efficacy and safety of CKD-828, a fixed-dose combination of S-amlodipine (the more active isomer of amlodipine besylate, which is calcium channel blocker and telmisartan (long acting angiotensin receptor blocker, in patients with hypertension inadequately controlled with S-amlodipine monotherapy.Patients and methods: Eligible patients (N=187 who failed to respond after 4-week S-amlodipine 2.5 mg monotherapy (sitting diastolic blood pressure [sitDBP] ≥90 mmHg to receive CKD-828 2.5/40 mg (n=63, CKD-828 2.5/80 mg (n=63, or S-amlodipine 2.5 mg (n=61 for 8 weeks. The primary efficacy endpoint, mean sitDBP change from baseline to Week 8, was compared between the combination (CKD-828 2.5/40 mg and CKD-828 2.5/80 mg and S-amlodipine monotherapy groups. The safety was assessed based on adverse events, vital signs, and physical examination findings.Results: After the 8

  7. Book Reviews

    Directory of Open Access Journals (Sweden)

    Jerome Rousseau

    1984-04-01

    Full Text Available - Henri J.M. Claessen, Ross H. Cordy, A study of prehistoric social change: The development of complex societies in the Hawaiian Islands, New York: Academic Press, 1981, 274 pp., Maps, ills., index, Appendices. - Th. van den End, C. Guillot, L’affaire Sadrach. Un essai de christianisation à Java au XIXe siècle. Editions de la Maison des Sciences de l’Homme, Paris 1981.374 pp. Etudes insulindiennes/Archipel 4. - Renée Hagesteijn, A. Milner, Kerajaan: Malay political culture on the eve of colonial rule. The Association for Asian Studies, Monograph no. XL, University of Arizona Press, Tucson, 1982. - P. van Hees, Emile Henssen, Gerretson en Indië. Bouma’s Boekhuis/Wolters Noordhoff, Groningen 1983. 231 blz. + los register. - M. Hekker, H.D. Kubitschek, Geschichte Indonesiens. Vom Altertum bis zur Gegenwart, Akademie Verlag, Berlin, 1981. xiii + 266 pp., I. Wessel (eds. - Huynh Kim Khánh, W.R. Smyses, The independent Vietnamese: Vietnamese communism between Russia and China, Athens, Ohio: Ohio University Center for International Studies, Southeast Asia Program, 1980, 143 pages, bibliography. - Saskia Keller, Sandra Hira, Van Priary tot en met De Kom. De geschiedenis van het verzet in Suriname, 1630-1940, Rotterdam: Uitgeverij Futile, 1982. - Gerrit J. Knaap, R.Z. Leirissa, Maluku Tengah di masa lampau. Gambaran sekilas lewat arsip abad sembilan belas, Penerbitan Sumber-Sumber Sejarah no. 13, Arsip Nasional Republik Indonesia, Jakarta 1982. XIV + 218 pp., Z.J. Manusama, A.B. Lapian (eds. - S. Kooijman, Tibor Bodrogi, Stammeskunst, Vol I, Australien, Ozeanien, Afrika, ed. by Tibor Bodrogi, 306 pp., 396 photographs (16 coloured, 13 sketch maps. Vol. II. Amerika, Asien, ed. by Tibor Bodrogi and Lajos Boglár, 274 pp., 238 photographs (16 coloured, 8 sketch maps. German translation of Tözsi Müvészet, Budapest, Corvina Kiadó, 1982., Lajos Boglár (eds. - H.M.J. Maier, R.G. Tol, Raja Ali Haji Ibn Ahmad, The Precious Gift (Tuhfat al-Nafis. An

  8. Relação entre concentração e rentabilidade no setor bancário Brasileiro A study on the relationship between concentration and profitability in the Brazilian banking industry

    Directory of Open Access Journals (Sweden)

    José Alves Dantas

    2011-04-01

    Full Text Available O estudo da rentabilidade bancária envolve duas linhas de discussão: (1 a performance dos bancos é importante para garantir a solidez da instituição e a estabilidade do sistema e (2 rentabilidade elevada pode indicar comportamento oportunista dos bancos, associado a um mercado concentrado. O propósito deste estudo é avaliar a evolução do grau de concentração da indústria bancária no Brasil e verificar se há relação entre o nível de rentabilidade das instituições e o grau de concentração do setor, utilizando ativos totais, operações de crédito e depósitos bancários, entre janeiro/2000 e dezembro/2009. Tendo como benchmark os parâmetros das autoridades antitruste brasileiras, não foram encontradas evidências de concentração no setor, embora o indicador de concentração tenha aumentado substancialmente a partir do final de 2008. Utilizando os parâmetros considerados nos EUA, foi constatado que, no final do período analisado, os indicadores mostram uma situação de "concentração moderada". Como um segundo objetivo do trabalho, foram testadas hipóteses baseadas no paradigma estrutura - conduta - performance, que pressupõe que menor competição decorrente de maior concentração resultaria em maior rentabilidade das instituições. Os resultados não corroboram as hipóteses em nenhuma das combinações de testes realizadas, seja porque os parâmetros são não significativos ou porque são negativos. Não são confirmadas, portanto, as previsões de que a maior concentração do mercado explicaria uma maior rentabilidade das instituições financeiras, conforme a hipótese estrutura - conduta - performance (HCP. Ao contrário, foram obtidas evidências de que a hipótese de estrutura eficiente (HEE explica, mais adequadamente, a rentabilidade no setor bancário nacional.The study of bank profitability involves two lines of discussion: (1 bank performance is important to guarantee the strength of the institution

  9. Tidal Energy System for On-Shore Power Generation

    Energy Technology Data Exchange (ETDEWEB)

    Bruce, Allan J

    2012-06-26

    Addressing the urgent need to develop LCOE competitive renewable energy solutions for US energy security and to replace fossil-fuel generation with the associated benefits to environment impacts including a reduction in CO2 emissions, this Project focused on the advantages of using hydraulic energy transfer (HET) in large-scale Marine Hydrokinetic (MHK) systems for harvesting off-shore tidal energy in US waters. A recent DOE resource assessment, identifies water power resources have a potential to meet 15% of the US electric supply by 2030, with MHK technologies being a major component. The work covered a TRL-4 laboratory proof-in-concept demonstration plus modeling of a 15MW full scale system based on an approach patented by NASA-JPL, in which submerged high-ratio gearboxes and electrical generators in conventional MHK turbine systems are replaced by a submerged hydraulic radial pump coupled to on-shore hydraulic motors driving a generator. The advantages are; first, the mean-time-between-failure (MTBF), or maintenance, can be extended from approximately 1 to 5 years and second, the range of tidal flow speeds which can be efficiently harvested can be extended beyond that of a conventional submerged generator. The approach uses scalable, commercial-off-the-shelf (COTS) components, facilitating scale-up and commercialization. All the objectives of the Project have been successfully met (1) A TRL4 system was designed, constructed and tested. It simulates a tidal energy turbine, with a 2-m diameter blade in up to a 2.9 m/sec flow. The system consists of a drive motor assembly providing appropriate torque and RPM, attached to a radial piston pump. The pump circulates pressurized, environmentally-friendly, HEES hydraulic fluid in a closed loop to an axial piston motor which drives an electrical generator, with a resistive load. The performance of the components, subsystems and system were evaluated during simulated tidal cycles. The pump is contained in a tank for

  10. EDITORIAL: Focus on Heart and Mind

    Science.gov (United States)

    Bodenschatz, Eberhard; Wolf, Fred

    2008-01-01

    tractable to support a comprehensive analysis of functional performance at the systems level. Analogously, experimental work increasingly probes the system dynamics simultaneously at multiple levels from cell to whole organ. Here an invaluable contribution of physics to the experimental characterization of large scale activity in cardiac and neuronal tissues is the currently emerging high level of quantitative precision and control. Long-term high precision recording of large scale activity patterns of neural and cardiac tissues increasingly supports the formulation of quantitative phenomenological theories of complex dynamical states as well the realization of algorithms for manipulating and controlling them. Both quantitative phenomenology and control are not only essential for bridging theory and experiment in complex systems; they are also indispensable for turning scientific insight into diagnostic progress and improved treatment for the affected heart and mind. The present Focus Issue in New Journal of Physics reflects well the richness and excitement of this currently rapidly evolving field. It combines theoretical and experimental approaches and covers analyses ranging from the organ level over investigations of model systems to the biophysics of individual cells. The articles below represent the first contributions to this collection and further additions will appear in the near future. Focus on Heart and Mind Contents 'Heart' contributions Spiral wave drift and complex-oscillatory spiral waves caused by heterogeneities in two-dimensional in vitro cardiac tissues Sung-Jae Woo, Jin Hee Hong, Tae Yun Kim, Byung Wook Bae and Kyoung J Lee Epicardial wavefronts arise from widely distributed transient sources during ventricular fibrillation in the isolated swine heart J M Rogers, G P Walcott, J D Gladden, S B Melnick, R E Ideker and M W Kay Efficient control of spiral wave location in an excitable medium with localized heterogeneities J Schlesner, V S Zykov, H Brandtst

  11. 12th WINFOCUS world congress on ultrasound in emergency and critical care.

    Science.gov (United States)

    Acar, Yahya; Tezel, Onur; Salman, Necati; Cevik, Erdem; Algaba-Montes, Margarita; Oviedo-García, Alberto; Patricio-Bordomás, Mayra; Mahmoud, Mustafa Z; Sulieman, Abdelmoneim; Ali, Abbas; Mustafa, Alrayah; Abdelrahman, Ihab; Bahar, Mustafa; Ali, Osama; Lester Kirchner, H; Prosen, Gregor; Anzic, Ajda; Leeson, Paul; Bahreini, Maryam; Rasooli, Fatemeh; Hosseinnejad, Houman; Blecher, Gabriel; Meek, Robert; Egerton-Warburton, Diana; Ćuti, Edina Ćatić; Belina, Stanko; Vančina, Tihomir; Kovačević, Idriz; Rustemović, Nadan; Chang, Ikwan; Lee, Jin Hee; Kwak, Young Ho; Kim, Do Kyun; Cheng, Chi-Yung; Pan, Hsiu-Yung; Kung, Chia-Te; Ćurčić, Ela; Pritišanac, Ena; Planinc, Ivo; Medić, Marijana Grgić; Radonić, Radovan; Fasina, Abiola; Dean, Anthony J; Panebianco, Nova L; Henwood, Patricia S; Fochi, Oliviero; Favarato, Moreno; Bonanomi, Ezio; Tomić, Ivan; Ha, Youngrock; Toh, Hongchuen; Harmon, Elizabeth; Chan, Wilma; Baston, Cameron; Morrison, Gail; Shofer, Frances; Hua, Angela; Kim, Sharon; Tsung, James; Gunaydin, Isa; Kekec, Zeynep; Ay, Mehmet Oguzhan; Kim, Jinjoo; Kim, Jinhyun; Choi, Gyoosung; Shim, Dowon; Lee, Ji-Han; Ambrozic, Jana; Prokselj, Katja; Lucovnik, Miha; Simenc, Gabrijela Brzan; Mačiulienė, Asta; Maleckas, Almantas; Kriščiukaitis, Algimantas; Mačiulis, Vytautas; Macas, Andrius; Mohite, Sharad; Narancsik, Zoltan; Možina, Hugon; Nikolić, Sara; Hansel, Jan; Petrovčič, Rok; Mršić, Una; Orlob, Simon; Lerchbaumer, Markus; Schönegger, Niklas; Kaufmann, Reinhard; Pan, Chun-I; Wu, Chien-Hung; Pasquale, Sarah; Doniger, Stephanie J; Yellin, Sharon; Chiricolo, Gerardo; Potisek, Maja; Drnovšek, Borut; Leskovar, Boštjan; Robinson, Kristine; Kraft, Clara; Moser, Benjamin; Davis, Stephen; Layman, Shelley; Sayeed, Yusef; Minardi, Joseph; Pasic, Irmina Sefic; Dzananovic, Amra; Pasic, Anes; Zubovic, Sandra Vegar; Hauptman, Ana Godan; Brajkovic, Ana Vujaklija; Babel, Jaksa; Peklic, Marina; Radonic, Vedran; Bielen, Luka; Ming, Peh Wee; Yezid, Nur Hafiza; Mohammed, Fatahul Laham; Huda, Zainal Abidin; Ismail, Wan Nasarudin Wan; Isa, W Yus Haniff W; Fauzi, Hashairi; Seeva, Praveena; Mazlan, Mohd Zulfakar

    2016-09-01

    veterans: a retrospective analysis from the first Croatian veteran's hospitalEdina Ćatić Ćuti, Stanko Belina, Tihomir Vančina, Idriz KovačevićA15 The challenge of AAA: unusual case of obstructive jaundiceEdina Ćatić Ćuti, Nadan RustemovićA16 Educational effectiveness of easy-made new simulator model for ultrasound-guided procedures in pediatric patients: vascular access and foreign body managementIkwan Chang, Jin Hee Lee, Young Ho Kwak, Do Kyun KimA17 Detection of uterine rupture by point-of-care ultrasound at emergency department: a case reportChi-Yung Cheng, Hsiu-Yung Pan, Chia-Te KungA18 Abdominal probe in the hands of interns as a relevant diagnostic tool in revealing the cause of heart failureEla Ćurčić, Ena Pritišanac, Ivo Planinc, Marijana Grgić Medić, Radovan RadonićA19 Needs assessment of the potential utility of point-of-care ultrasound within the Zanzibar health systemAbiola Fasina, Anthony J. Dean, Nova L. Panebianco, Patricia S. HenwoodA20 Ultrasonographic diagnosis of tracheal compressionOliviero Fochi, Moreno Favarato, Ezio BonanomiA21 The role of ultrasound in the detection of lung infiltrates in critically ill patients: a pilot studyMarijana Grgić Medić, Ivan Tomić, Radovan RadonićA22 The SAFER Lasso; a novel approach using point-of-care ultrasound to evaluate patients with abdominal complaints in the emergency departmentYoungrock Ha, Hongchuen TohA23 Awareness and use of clinician-performed ultrasound among clinical clerkship facultyElizabeth Harmon, Wilma Chan, Cameron Baston, Gail Morrison, Frances Shofer, Nova Panebianco, Anthony J. DeanA24 Clinical outcomes in the use of lung ultrasound for the diagnosis of pediatric pneumoniasAngela Hua, Sharon Kim, James TsungA25 Effectiveness of ultrasound in hypotensive patientsIsa Gunaydin, Zeynep Kekec, Mehmet Oguzhan AyA26 Moderate-to-severe left ventricular ejection fraction related to short-term mortality of patients with post-cardiac arrest syndrome after out-of-hospital cardiac arrest

  12. From the Editor

    Directory of Open Access Journals (Sweden)

    Ugur DEMIRAY

    2006-04-01

    project that examined student perceptions of the psychosocial learning environment in a distance education classroom. The study utilized a survey instrument, Distance Education Learning Environments Survey (DELES that was distributed as a pre-test/post-test to three sections of the same course taught in three distinct formats: traditional classroom instruction, distance learning, and hybrid (partially on-line/partially face-to-face. The fifth article came from Brasil, written by Profa. Dra. Margarita V. GOMEZ. Her subject is entitled as “Contemporary Spheres for the Teaching Education: Freire's principles”. She focuses on Freire's cogitation on Information Technology (IT, resources for education have been known since the decade of the 50s. Within the internet context, the proposal implies a digital writing and reading ability that is based on communication and dialogue skills and, as fundamental strategies for reading the world, the real/virtual world, the knowledge of the daily speech, of writing and reading within a multi-diversification of digitally generated texts. She stated that long distance education through the internet from Freire's prospective is supported by the principles of popular education, that is: critical proximity to reality, radicalism (there is no neutral education, announcement, political organization, text-context relation, dialogical methodology without disowning the culture of silence that operates in the internet and this what it generates. I hope it is very interesting article to learn about Freire's principles for Tojde readers The sixth article which is jointly written by Prof. Murray TUROFF, Prof. Starr Roxanne HILTZ, Xiang YAO Information Systems Department, New Jersey Institute of Technology, Zheng LI from Pace University, Dr Yuanqiong WANG from Towson University and Dr. Hee-Kyung CHO from Fairleigh Dickinson University, USA. Their article is titled “Online Collaborative Learning Enhancement Through the Delphi Method”. Their paper