WorldWideScience

Sample records for heavy axle load

  1. Impact of overweight vehicles (with heavy axle loads) on bridge deck deterioration.

    Science.gov (United States)

    2012-03-01

    Bridge deck slabs develop compressive stresses from global flexural deformation and locally from high-level : wheel loads when it is subjected to overweight trucks. This study quantified the impact of overweight vehicles : with heavy axle loads on br...

  2. Analysis of minimum rail size in heavy axle load environment

    Science.gov (United States)

    2013-04-15

    The effects of increasing axle loads on rail integrity are examined in this paper. In the present context, rail integrity refers to the prevention and control of rail failures. Rail failures usually occur because cracks or defects develop and grow fr...

  3. Part 1 : heavy axle load revenue service mega site testing 2005-2012.

    Science.gov (United States)

    2014-06-01

    Since 2005, the Federal Railroad Administration : and the Association of American Railroads have : jointly funded a heavy axle load (HAL) revenue : service testing program with several objectives. : One objective is to determine the effects of HAL : ...

  4. Part 2 : heavy axle load revenue service mega site testing 2005-2012.

    Science.gov (United States)

    2014-06-01

    Since 2005, the Federal Railroad Administration : and the Association of American Railroads have : jointly funded a heavy axle load (HAL) revenue : service testing program, with several objectives. : One objective is to determine the effects of HAL :...

  5. Heavy and Overweight Vehicle Brake Testing: Five-Axle Combination Tractor-Flatbed Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Lascurain, Mary Beth [ORNL; Capps, Gary J [ORNL; Franzese, Oscar [ORNL

    2013-10-01

    The Federal Motor Carrier Safety Administration, in coordination with the Federal Highway Administration, sponsored the Heavy and Overweight Vehicle Brake Testing (HOVBT) program in order to provide information about the effect of gross vehicle weight (GVW) on braking performance. Because the Federal Motor Carrier Safety Regulations limit the number of braking system defects that may exist for a vehicle to be allowed to operate on the roadways, the examination of the effect of brake defects on brake performance for increased loads is also relevant. The HOVBT program seeks to provide relevant information to policy makers responsible for establishing load limits, beginning with providing test data for a combination tractor/trailer. This testing was conducted on a five-axle combination vehicle with tractor brakes meeting the Reduced Stopping Distance requirement rulemaking. This report provides a summary of the testing activities, the results of various analyses of the data, and recommendations for future research. Following a complete brake rebuild, instrumentation, and brake burnish, stopping tests were performed from 20 and 40 mph with various brake application pressures (15 psi, 25 psi, 35 psi, 45 psi, 55 psi, and full system pressure). These tests were conducted for various brake conditions at the following GVWs: 60,000, 80,000, 91,000, 97,000, 106,000, and 116,000 lb. The 80,000-lb GVWs included both balanced and unbalanced loads. The condition of the braking system was also varied. To introduce these defects, brakes (none, forward drive axle, or rear trailer axle) were made inoperative. In addition to the stopping tests, performance-based brake tests were conducted for the various loading and brake conditions. Analysis of the stopping test data showed the stopping distance to increase with load (as expected) and also showed that more braking force was generated by the drive axle brakes than the trailer axle brakes. The constant-pressure stopping test data

  6. Dynamic Axle Load of an Automotive Vehicle When Driven on a Mobile Measurement Platform

    OpenAIRE

    Jagiełowicz-Ryznar C.

    2014-01-01

    An analysis of the dynamic axle load of an automotive vehicle (AV) when it is driven on a mobile measurement platform is presented in this paper. During the ride, the time characteristic of the dynamic force N(t), acting on the axle, was recorded. The effect of the vehicle axle mass on the maximum dynamic force value and the dynamic coefficient were studied. On this basis it was attempted to calculate the total vehicle’s weight. Conclusions concerning the dynamic loads of the vehicle axles in...

  7. Dynamic axle and wheel loads identification: laboratory studies

    Science.gov (United States)

    Zhu, X. Q.; Law, S. S.

    2003-12-01

    Two methods have been reported by Zhu and Law to identify moving loads on the top of a bridge deck. One is based on the exact solution (ESM) and the other is based on the finite element formulation (FEM). Simulation studies on the effect of different influencing factors have been reported previously. This paper comparatively studies the performances of these two methods with experimental measurements obtained from a bridge/vehicle system in the laboratory. The strains of the bridge deck are measured when a model car moves across the bridge deck along different paths. The moving loads on the bridge deck are identified from the measured strains using these two methods, and the responses are reconstructed from the identified loads for comparison with the measured responses to verify the performances of these methods. Studies on the identification accuracy due to the effect of the number of vibration mode used, the number of measuring points and eccentricities of travelling paths are performed. Results show that the ESM could identify the moving loads individually or as axle loads when they are travelling at an eccentricity with the sensors located close to the travelling path of the forces. And the accuracy of the FEM is dependent on the amount of measured information used in the identification.

  8. Sustainable railway bridges with higher axle loads:monitoring examples from northern Sweden

    OpenAIRE

    Elfgren, Lennart; Enochsson, Ola; Täljsten, Björn; Paulsson, Björn

    2007-01-01

    Monitoring of several railway bridges has been carried out in northern Sweden in order to increase the allowable axle load. The work is part of a European Integrated Project "Sustainable Bridges - Assessment for Future Traffic Demands and Longer Lives". The paper describes the project and gives some examples of applications. Monitoring of several railway bridges has been carried out in northern Sweden in order to increase the allowable axle load. The work is part of a European Integrated P...

  9. Residual fatigue lifetime estimation of railway axles for various loading spectra

    Czech Academy of Sciences Publication Activity Database

    Pokorný, Pavel; Hutař, Pavel; Náhlík, Luboš

    2016-01-01

    Roč. 82, APR (2016), s. 25-32 ISSN 0167-8442 R&D Projects: GA MŠk(CZ) EE2.3.20.0214; GA MŠk(CZ) ED1.1.00/02.0068 Institutional support: RVO:68081723 Keywords : Fatigue failure * Residual fatigue lifetime * Crack propagation * Railway axle * Load spectrum Subject RIV: JL - Materials Fatigue, Friction Mechanics Impact factor: 2.659, year: 2016

  10. Total Weight and Axle Loads of Truck Units in the Transport of Timber Depending on the Timber Cargo

    Directory of Open Access Journals (Sweden)

    Grzegorz Trzciński

    2018-03-01

    Full Text Available When transporting timber, the high variability of species, assortments and moisture content of the wood raw material does not allow the weight of the transported timber to be precisely determined. This often contributes to the excessive weight loading of the entire truck unit. The aim of the research is to present the variability of the total weight of truck units with wood cargoes (GVW—gross vehicle weight depending on the weight of the empty unit and the transported timber load, as well as to analyze the changes in GVW, unit loads of wood and load on individual truck unit axles depending on the season. This study analyzes the total weight of truck units for 376 transports of Scots pine timber at different times of the year. The total weight of the truck units depends on the weight of an empty unit and the weight of the load. GVW was determined by using a weighbridge to weigh the vehicles and then the empty unit after unloading. The weight of the load was obtained as the difference between GVW and the tare. It was found that GVW differed significantly depending on the truck unit used, ranging from 43.60–58.80 Mg, often exceeding permissible limits for public roads. The individual axle loads for various truck units were also analyzed. The obtained results indicate that these loads are more equally distributed in the case of five-axle trucks compared to six-axle ones.

  11. Analysis of axle and vehicle load properties through Bayesian networks based on weigh-in-motion data

    NARCIS (Netherlands)

    Morales Napoles, O.; Steenbergen, R.D.J.M.

    2014-01-01

    Weigh-in-Motion (WIM) systems are used, among other applications, in pavement and bridge reliability. The system measures quantities such as individual axle load, vehicular loads, vehicle speed, vehicle length and number ofaxles. Because ofthe nature ofúamc configuration, the quantities measured are

  12. Cost-benefit analysis of the construction of different flexible pavement structures considering the axle load and type of binder

    Directory of Open Access Journals (Sweden)

    Lucas Dotto Bueno

    2016-08-01

    Full Text Available The status of Brazilian highways reflects a deficient pavement performance when they are subjected to loadings imposed by heavy traffic. Current legislation, as enacted by Contran (National Traffic Council, has increased the axle weight limit for cargo vehicles by up to 10%. Therefore, the aim of this study was to determine a cost-benefit ratio by using different types of structures, asphalt binders and load intensities. Typical pavements were determined and then analyzed by the software AEMC (SisPav to obtain the horizontal tensile strain (εt values at the bottom of the asphalt concrete layer and, later, the NFATIGUE value. It was found that the increase in weight, within values covered by legislation, might result in a reduction of approximately 50% in the NFATIGUE value for the pavement structures analyzed. As for economic impact, the same weight increase caused a mean increase of 120% in the cost of repeated loading on pavement structures (R$ NFATIGUE-1. It was also observed that structures with more robust asphalt concrete layers can provide the best R$ NFATIGUE-1 ratios. The best results for granular materials were found with thinner layers, associated with a thicker coating. The benefits of modified binders were shown by the analyses of the best structural options: both the polymer-modified binder and the rubber asphalt binder offer significant structural and economic improvements to the structure.

  13. Heavy-Load Lifting

    DEFF Research Database (Denmark)

    Bloomquist, Kira; Oturai, Peter; Steele, Megan L

    2018-01-01

    of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal....... repetition maximum (RM), two sets of 15-20 repetitions) and heavy-load (85-90% 1RM, three sets of 5-8 repetition) upper-extremity resistance exercise separated by a one-week wash-out period. Swelling was determined by bioimpedance spectroscopy and dual energy x-ray absorptiometry, with breast cancer......-related lymphedema symptoms (heaviness, swelling, pain, tightness) reported using a numeric rating scale (0-10). Order of low- versus heavy-load was randomized. All outcomes were assessed pre-, immediately post-, and 24- and 72-hours post-exercise. Generalized estimating equations were used to evaluate changes over...

  14. A heavy load for heavy ions

    CERN Multimedia

    2003-01-01

    On 25 September, the two large coils for the dipole magnet of ALICE, the LHC experiment dedicated to heavy ions, arrived at Point 2 on two heavy load trucks after a 1200 km journey from their assembly in Vannes, France.

  15. Effect of the load of drive axles and high of the curtain on stress-strain properties of the tractor

    Directory of Open Access Journals (Sweden)

    Tomáš Šmerda

    2007-01-01

    Full Text Available The goal of the experimental measurement was determination of relation among weight load of the tractor together, hitch height changes and drawbar characteristic. The measurement was realized on chassis dynamometer at MUAF in Brno. The first step consisted of rated speed characteristics measurement in conformity with OECD demands. The drawbar characteristic was measured under two selected gears. Adding 980 kg to the nominal wight of the tractor brought increasing maximal drawbar power and drawbar force together with decreasing of slip. The highest differences were observed during the mesurement of fifth gear shifted. The drawbar force grew up to 18.9% as well as the maximal drawbar power (15.2%. The maximal drawbar power at ninth gear gave 62.8 kW. The hitch height was setting to 0.54 m; 0.64 m and 0.74 m. When the hitch height was set from 0.54 m to 0.74 m the drawbar force an power on front axle was lower by reason of load reduction. As can be noticed from the final drawbar characteristics, both curves are identical up to border of maximal drawbar power. Small differences in the area of the highest slips can be ascribed to the rolling resistance.

  16. An Experimental Study on Hysteresis Characteristics of a Pneumatic Braking System for a Multi-Axle Heavy Vehicle in Emergency Braking Situations

    Directory of Open Access Journals (Sweden)

    Zhe Wang

    2017-08-01

    Full Text Available This study aims to investigate the hysteresis characteristics of a pneumatic braking system for multi-axle heavy vehicles (MHVs. Hysteresis affects emergency braking performance severely. The fact that MHVs have a large size and complex structure leads to more nonlinear coupling property of the pneumatic braking system compared to normal two-axle vehicles. Thus, theoretical analysis and simulation are not enough when studying hysteresis. In this article, the hysteresis of a pneumatic brake system for an eight-axle vehicle in an emergency braking situation is studied based on a novel test bench. A servo drive device is applied to simulate the driver’s braking intensions normally expressed by opening or moving speed of the brake pedal. With a reasonable arrangement of sensors and the NI LabVIEW platform, both the delay time of eight loops and the response time of each subassembly in a single loop are detected in real time. The outcomes of the experiment show that the delay time of each loop gets longer with the increase of pedal opening, and a quadratic relationship exists between them. Based on this, the pressure transient in the system is fitted to a first-order plus time delay model. Besides, the response time of treadle valve and controlling pipeline accounts for more than 80% of the loop’s total delay time, indicating that these two subassemblies are the main contributors to the hysteresis effect.

  17. Ride comfort optimization of a multi-axle heavy motorized wheel dump truck based on virtual and real prototype experiment integrated Kriging model

    Directory of Open Access Journals (Sweden)

    Bian Gong

    2015-06-01

    Full Text Available The optimization of hydro-pneumatic suspension parameters of a multi-axle heavy motorized wheel dump truck is carried out based on virtual and real prototype experiment integrated Kriging model in this article. The root mean square of vertical vibration acceleration, in the center of sprung mass, is assigned as the optimization objective. The constraints are the natural frequency, the working stroke, and the dynamic load of wheels. The suspension structure for the truck is the adjustable hydro-pneumatic suspension with ideal vehicle nonlinear characteristics, integrated with elastic and damping elements. Also, the hydraulic systems of two adjacent hydro-pneumatic suspension are interconnected. Considering the high complexity of the engineering model, a novel kind of meta-model called virtual and real prototype experiment integrated Kriging is proposed in this article. The interpolation principle and the construction of virtual and real prototype experiment integrated Kriging model were elucidated. Being different from traditional Kriging, virtual and real prototype experiment integrated Kriging combines the respective advantages of actual test and Computer Aided Engineering simulation. Based on the virtual and real prototype experiment integrated Kriging model, the optimization results, obtained by experimental verification, showed significant improvement in the ride comfort by 12.48% for front suspension and 11.79% for rear suspension. Compared with traditional Kriging, the optimization effect was improved by 3.05% and 3.38% respectively. Virtual and real prototype experiment integrated Kriging provides an effective way to approach the optimal solution for the optimization of high-complexity engineering problems.

  18. The Effect of Flexible Pavement Mechanics on the Accuracy of Axle Load Sensors in Vehicle Weigh-in-Motion Systems.

    Science.gov (United States)

    Burnos, Piotr; Rys, Dawid

    2017-09-07

    Weigh-in-Motion systems are tools to prevent road pavements from the adverse phenomena of vehicle overloading. However, the effectiveness of these systems can be significantly increased by improving weighing accuracy, which is now insufficient for direct enforcement of overloaded vehicles. Field tests show that the accuracy of Weigh-in-Motion axle load sensors installed in the flexible (asphalt) pavements depends on pavement temperature and vehicle speeds. Although this is a known phenomenon, it has not been explained yet. The aim of our study is to fill this gap in the knowledge. The explanation of this phenomena which is presented in the paper is based on pavement/sensors mechanics and the application of the multilayer elastic half-space theory. We show that differences in the distribution of vertical and horizontal stresses in the pavement structure are the cause of vehicle weight measurement errors. These studies are important in terms of Weigh-in-Motion systems for direct enforcement and will help to improve the weighing results accuracy.

  19. An appraisal of mass differences between individual tyres, axles and axle groups of a selection of heavy vehicles in South Africa

    CSIR Research Space (South Africa)

    De Beer, Morris

    2012-06-01

    Full Text Available study of 2 666 heavy vehicles (HVs) with Gross Combination Mass, (GCM) > 3 500 kg was conducted, where the mass (or weight) of each tyre (approximately 47 242 tyres (or wheels)) was measured. The measurements were done at slow speed over the SIM device...

  20. Performance Deterioration of Heavy-Haul Railway Bridges under Fatigue Loading Monitored by a Multisensor System

    Directory of Open Access Journals (Sweden)

    Zhiwu Yu

    2018-01-01

    Full Text Available Heavy-haul railway bridges play an increasingly essential role in the transportation in China due to the increasing transport volume. The performance deterioration of the scale models of a typical heavy-haul railway bridge under fatigue loading is monitored in this work, based on a multisensor system including the fiber-reinforced polymer optical fiber Bragg grating and electrical resistance strain gauges, linear variable displacement transducer, and accelerometer. Specifically, by monitoring/observing on the failure mode, fatigue life, load-midspan deflection response, material strain development, and so forth, this work develops an S-N model by comparing the relationship between fatigue life and rebar stress range with that between fatigue life and load level and proposes a damage evolution model considering the coupling of the stiffness degradation and inelastic deformation of specimens. It is found that the fatigue life of specimens is determined by the fatigue life of the rebar at the bottom and it may be lower than 2.0 million cycles with a 30-ton axle weight when environmental factors are taken into account. The predictions of the models agree well with experimental results. Therefore, this work furthers the understanding of the fatigue performance deterioration of the bridges by using a multisensor system.

  1. Modelling vertical uniform contact stress of heavy vehicle tyres

    CSIR Research Space (South Africa)

    Steenkamp, Anton J

    2016-07-01

    Full Text Available over the selected operating range of 25 kN to 45 kN which is the typical load range for heavy vehicle tyres due to legal axle load limits. The polynomial formulas require only the tyre inflation pressure and vertical tyre load as inputs, in order...

  2. Heavy Load Rollers in Logistic Systems

    Directory of Open Access Journals (Sweden)

    B. Künne

    2003-01-01

    Full Text Available Wheels with polyurethane bandages are in common use in logistic systems with friction gear actuation. Many research projects have studied the mechanical construction of these heavy load wheels. The studies have been theoretical as well as experimental. Research interests at the department of machine elements include the wear in the presence of intermediate material on the contact area between the bandage surface and the contact surface on which the wheel rolls off. This problem, which is observed when examining this tribochemical system, has not been studied before. Within this project both one-phase intermediate materials such as sand, water, cutting-cooling-emulsion, metal splinters and two-phase intermediate materials such as sand/water and combinations of the latter were taken into consideration. In addition, the exposure of the bandage hardness, the cross linking agent of the polyurethane, the mechanical stress, and the slip are observed. The analysis of the experimental results indicates that friction gear actuators can be constructed abrasion-optimised, taking into account special interfering effects in the form of intermediate materials in the contact area.

  3. WHEELSET AXLE WITH THE CAVITY OF UNIFORM CROSS SECTION

    Directory of Open Access Journals (Sweden)

    S. R. Kolesnykov

    2014-10-01

    Full Text Available Purpose. Due to operation in complex loading conditions, the rolling stock wheelsets should provide high reliability, since the train traffic safety largely depends on them. Design and technical condition of wheelsets affect the smoothness, intensity of forces generated by the interaction between the car and track, and the motion resistance. Specificity of the axle operation consists in the fact that it undergoes the bending stresses under loading. These stresses are unevenly distributed along the cross-sectional area, reaching the highest values in the outer fibers and the minimal values in the internal ones. This aspect sets the problem of replacement of the uniform cross section with the hollow cross section. The disadvantages of hollow axle design, which are used at the present time, should include a significant manufacturing complexity of the variable section cavity. The purpose is to develop a modernized design of the wheelset axle. Methodology. A construction of the hollow axle having an inner longitudinal cylindrical through hole of the constant diameter throughout its length was proposed. The item is made of steel seamless tube. The inner surface of the tube is treated by mechanical means to remove the voltage concentrations in the internal longitudinal cylindrical through hole, which has a constant diameter along the entire length of the axle. Findings. Application of this design will facilitate manufacturing of the hollow axle and the machining of the inner longitudinal through hole, while retaining all the use advantages of the hollow axle in the rolling stock wheel pairs. Another use advantage of the hollow axle of this design is the absence of partial heterogeneity of the metal, which is inevitably, occurs during the solid axles blanking. Originality. A new design of the wheelset hollow axle of railway rolling stock was proposed. Practical value. Introduction of the new design simplifying the manufacture and mechanical treatment of

  4. Fatigue lifetime estimation of railway axles

    Czech Academy of Sciences Publication Activity Database

    Náhlík, Luboš; Pokorný, Pavel; Ševčík, Martin; Fajkoš, R.; Matušek, P.; Hutař, Pavel

    2017-01-01

    Roč. 73, MAR (2017), s. 139-157 ISSN 1350-6307 R&D Projects: GA MŠk LM2015069; GA MŠk(CZ) ED1.1.00/02.0068 Institutional support: RVO:68081723 Keywords : Residual fatigue lifetime * Railway axle * Variable amplitude loading * Fatigue crack propagation * Damage tolerance methodology Subject RIV: JL - Materials Fatigue, Friction Mechanics OBOR OECD: Audio engineering, reliability analysis Impact factor: 1.676, year: 2016

  5. Occupational lifting of heavy loads and preterm birth:

    DEFF Research Database (Denmark)

    Runge, Stine Bjerrum; Pedersen, Jacob Krabbe; Svendsen, Susanne Wulff

    2013-01-01

    To examine the association between occupational lifting during pregnancy and preterm birth. The risk of preterm birth was estimated for total burden lifted per day and number of medium and heavy loads lifted per day.......To examine the association between occupational lifting during pregnancy and preterm birth. The risk of preterm birth was estimated for total burden lifted per day and number of medium and heavy loads lifted per day....

  6. Behavior of an operating floor subjected to heavy load drops

    International Nuclear Information System (INIS)

    Levin, H.A.; Chugh, S.C.; Goodyear, W.D.; Hall, W.J.; Tracy, T.J.

    1984-01-01

    A structural evaluation of the behavior of a Boiling Water Reactor operating floor subjected to postulated heavy load impact is presented relative to the evaluation of nuclear industry requirements for addressing the safe handling of heavy loads. A methodology for evaluation of important modes of structural response is presented along with a specification of performance limits that are consistent with desired functional requirements of the operating floor system. Options for improving undesirable behavior are discussed based upon an understanding of the physical phenomena involved, ultimately factoring this into a modification program. Reference is made to recent test experience that is applicable to the improvement of structural performance in modes of high shear ductility. Other relevant information is referenced that is applicable to the overall structural evaluation of nuclear power plant heavy load handling operations

  7. Spiral loaded cavities for heavy ion acceleration

    International Nuclear Information System (INIS)

    Schempp, A.; Klein, H.

    1976-01-01

    A transmission line theory of the spiral resonator has been performed and the calculated and measured properties will be compared. Shunt impedances up to 50 MΩ/m have been measured. In a number of high power tests the structure has been tested and its electrical and mechanical stability has been investigated. The static frequency shift due to ponderomotoric forces was between 0.2 and 50 kHz/kW dependent on the geometrical parameters of the spirals. The maximum field strength obtained on the axis was 16 MV/m in pulsed operation and 9.2 MV/m in cw, corresponding to a voltage gain per cavity of up to 0.96 MV. The results show that spiral resonators are well suited as heavy ion accelerator cavities. (author)

  8. Axl is not an indispensable factor for Zika virus infection in mice.

    Science.gov (United States)

    Wang, Zhao-Yang; Wang, Zai; Zhen, Zi-Da; Feng, Kai-Hao; Guo, Jing; Gao, Na; Fan, Dong-Ying; Han, Dai-Shu; Wang, Pei-Gang; An, Jing

    2017-08-01

    Recently, Zika virus (ZIKV) outbreak has been associated with a sharp increase in cases of Guillain-Barré syndrome and severe fetal abnormalities. However, the mechanism underlying the interaction of ZIKV with host cells is not yet clear. Axl, a receptor tyrosine kinase, is postulated as a receptor for ZIKV entry; however, its in vivo role during ZIKV infection and its impact on the outcome of the disease have not been fully characterized and evaluated. Moreover, there are contradictory results on its involvement in ZIKV infection. Here we utilized Axl-deficient mice (Axl-/-) and their littermates (Axl+/-) to study the in vivo role of Axl in ZIKV infection. Our results showed that both Axl+/- and Axl-/- suckling mice supported the replication of ZIKV and presented clinical manifestations. No significant difference has been found between Axl-deficient mice and their littermates in terms of the survival rate, clinical manifestations, viral load, ZIKV distribution and histopathological changes in major organs. These results therefore indicate that Axl is not an indispensable factor for ZIKV infection in mice.

  9. Metrological approach to the force exerted by the axle of a road vehicle in motion carrying liquid

    International Nuclear Information System (INIS)

    Faruolo, Luciano Bruno; Pinto, Fernando Augusto de Noronha Castro

    2016-01-01

    Weigh-in-motion (WIM) systems are used for identifying the dynamic force exerted on the ground by axles of a vehicle. These systems are important for monitoring the gross vehicle weight and the vehicle axle load. Overweighted trucks on the roads increase pavement damage and traffic accidents. Knowing the accuracy of WIM systems is necessary. In the case of liquid transport the ‘sloshing effect’ affects this accuracy. This paper aims to analyze the dynamic measurement of the axle forces in vehicles carrying liquid during WIM up to 6 km h −1 . Laboratory experiments using one vehicle with six axles and liquid loads on different levels in weighing instruments are presented. A non-linear computational multi-mass-springs model was developed and laboratory experiments were carried out to show the acceleration influences on axle forces of vehicles with six axles and with and without baffles to vary the ‘sloshing effect’. (paper)

  10. Analysis of Tendencies Towards Changes in Temperatures of Railway Vehicle Axle Boxes

    Directory of Open Access Journals (Sweden)

    Olegas Lunys

    2012-11-01

    Full Text Available The paper analyzes variations in the temperature of axle-box heating of railroad rolling stock considering two modes of the train - driving and parking position. Additionally, the article describes the influence of the axle load and season on the heat of the axle-box, forecasts intolerable residual resources and explains a possibility of detecting likely breakage at the very beginning of defects. The paper also deals with scientific literature related to axle-box heating and focuses on the conducted practical and theoretical experiments. The carried out research has established the rates of operating heating and critical heating. The application of numerical values for the algorithm of automatic control devices could help with detecting the breakdowns of the axle-box before they reach a critical state and assist in forecasting residual operating resources.

  11. Impact of increasing freight loads on rail substructure from fracking sand transportation.

    Science.gov (United States)

    2014-03-01

    In this report the effect of surface infiltration of frac sand and heavy axle loads (HALs) were studied for their impact on the ballast layer. : Different combinations of ballast and fracking sand were constructed to observe long term trends of defor...

  12. AXL mediates resistance to cetuximab therapy.

    Science.gov (United States)

    Brand, Toni M; Iida, Mari; Stein, Andrew P; Corrigan, Kelsey L; Braverman, Cara M; Luthar, Neha; Toulany, Mahmoud; Gill, Parkash S; Salgia, Ravi; Kimple, Randall J; Wheeler, Deric L

    2014-09-15

    The EGFR antibody cetuximab is used to treat numerous cancers, but intrinsic and acquired resistance to this agent is a common clinical outcome. In this study, we show that overexpression of the oncogenic receptor tyrosine kinase AXL is sufficient to mediate acquired resistance to cetuximab in models of non-small cell lung cancer (NSCLC) and head and neck squamous cell carcinoma (HNSCC), where AXL was overexpressed, activated, and tightly associated with EGFR expression in cells resistant to cetuximab (Ctx(R) cells). Using RNAi methods and novel AXL-targeting agents, we found that AXL activation stimulated cell proliferation, EGFR activation, and MAPK signaling in Ctx(R) cells. Notably, EGFR directly regulated the expression of AXL mRNA through MAPK signaling and the transcription factor c-Jun in Ctx(R) cells, creating a positive feedback loop that maintained EGFR activation by AXL. Cetuximab-sensitive parental cells were rendered resistant to cetuximab by stable overexpression of AXL or stimulation with EGFR ligands, the latter of which increased AXL activity and association with the EGFR. In tumor xenograft models, the development of resistance following prolonged treatment with cetuximab was associated with AXL hyperactivation and EGFR association. Furthermore, in an examination of patient-derived xenografts established from surgically resected HNSCCs, AXL was overexpressed and activated in tumors that displayed intrinsic resistance to cetuximab. Collectively, our results identify AXL as a key mediator of cetuximab resistance, providing a rationale for clinical evaluation of AXL-targeting drugs to treat cetuximab-resistant cancers. Cancer Res; 74(18); 5152-64. ©2014 AACR. ©2014 American Association for Cancer Research.

  13. Mass balance approaches to assess critical loads and target loads of heavy metals for terrestrial and aquatic ecosystems

    NARCIS (Netherlands)

    Vries, de W.; Groenenberg, J.E.; Posch, M.

    2015-01-01

    Critical loads of heavy metals address not only ecotoxicological effects on organisms in soils and surface waters, but also food quality in view of public health. A critical load for metals is the load resulting at steady state in a metal concentration in a compartment (e.g. soil solution, surface

  14. IDEAL BRAKE FORCE DISTRIBUTION BETWEEN THE AXLES OF THE TWO-AXLE VEHICLE SERVICE BRAKE APPLICATIONS

    Directory of Open Access Journals (Sweden)

    M. Podryhalo

    2015-07-01

    Full Text Available The obtained analytical expressions allow us to evaluate the stability of two-axle vehicles at various slowdowns. An analytical expression for calculating the ideal according to condition stability ensuring of a two-axle vehicle at service brake applications of brake force distribution allows to offer automatic control devices for brake force adjucement. With decellerationg growth of the two-axle vehicle at service braking the braking force acting on the front axle should decrease relative to the brake force on the rear axle.

  15. Baseline axle load survey in Malawi - 2014

    CSIR Research Space (South Africa)

    Roux, M

    2015-07-01

    Full Text Available of 50.4%. The average overloaded mass on the 1 356 overloaded vehicles was 4 264 kg, representing an average degree of overloading of 26.1%. Weigh data from 4 of the 5 permanent weighbridges in Malawi were also analysed to compare the extent and degree...

  16. [Mapping Critical Loads of Heavy Metals for Soil Based on Different Environmental Effects].

    Science.gov (United States)

    Shi, Ya-xing; Wu, Shao-hua; Zhou, Sheng-lu; Wang, Chun-hui; Chen, Hao

    2015-12-01

    China's rapid development of industrialization and urbanization causes the growing problem of heavy metal pollution of soil, threatening environment and human health. Therefore, prevention and management of heavy metal pollution become particularly important. Critical loads of heavy metals are an important management tool that can be utilized to prevent the occurrence of heavy metal pollution. Our study was based on three cases: status balance, water environmental effects and health risks. We used the steady-state mass balance equation to calculate the critical loads of Cd, Cu, Pb, Zn at different effect levels and analyze the values and spatial variation of critical loads. In addition, we used the annual input fluxes of heavy metals of the agro-ecosystem in the Yangtze River delta and China to estimate the proportion of area with exceedance of critical loads. The results demonstrated that the critical load value of Cd was the minimum, and the values of Cu and Zn were lager. There were spatial differences among the critical loads of four elements in the study area, lower critical loads areas mainly occurred in woodland and high value areas distributed in the east and southwest of the study area, while median values and the medium high areas mainly occurred in farmland. Comparing the input fluxes of heavy metals, we found that Pb and Zn in more than 90% of the area exceeded the critical loads under different environmental effects in the study area. The critical load exceedance of Cd mainly occurred under the status balance and the water environmental effect, while Cu under the status balance and water environmental effect with a higher proportion of exceeded areas. Critical loads of heavy metals at different effect levels in this study could serve as a reference from effective control of the emissions of heavy metals and to prevent the occurrence of heavy metal pollution.

  17. Evaluation of some heavy metals loading in dust fall of three ...

    African Journals Online (AJOL)

    Generally for the three sites used, the heavy metal concentrations decreased in the following order: Mn>Zn>Pb>Ni>Cu>Cd. This implies that dust-fall in the parks are heavily loaded with some heavy metals that are of concentrations above Romania standard threshold limit for Cd and Pb while concentration values obtained ...

  18. Lifting an unexpectedly heavy object : the effects on low-back loading and balance loss

    NARCIS (Netherlands)

    van der Burg, J C; van Dieën, J H; Toussaint, H M

    OBJECTIVE: This study evaluates the effects of lifting an unexpectedly heavy object on low-back loading and loss of balance. BACKGROUND: It is often suggested that lifting an unexpectedly heavy object may be a major risk factor for low-back pain. This may lead to an increase in muscle activation,

  19. Development of heavy load carrying vehicle for nuclear power station

    International Nuclear Information System (INIS)

    Terabayashi, Yasuharu; Oono, Hiroo; Aizu, Takao; Kawaguchi, Kaname; Yamanaka, Masayuki; Hirobe, Tamio; Inagaki, Yoshiaki.

    1985-01-01

    In nuclear power stations, in order to carry out sound and stable operation, the routine inspection and regular inspection of machinery and equipment are performed, therefore, the transportation of heavy things is frequently carried out. Especially, the transportation of heavy things over the steps of passages and stairs requires much labor. Therefore, Chubu Electric Power Co., Inc. and Chubu Plant Service Co., Ltd. carried out the research on the development of a vehicle for transporting heavy components of nuclear power plants. In this research, it was aimed at developing a vehicle which can carry heavy components and get over a step, climb and descend stairs, and run through a narrow passage having many curves as well as running on flat ground. For this purpose, the actual state of the transportation of heavy things was investigated during the regular inspection of a nuclear power station, and on the basis of this results, a prototype vehicle was made and tested. Thereafter, a transporting vehicle of actual scale was made and tested. The investigation of actual state and the examination of the fundamental concept, the design, trial manufacture and verifying test are reported. (Kako, I.)

  20. Pavement Response to Variable Tyre Pressure of Heavy Vehicles

    Directory of Open Access Journals (Sweden)

    Arshad Ahmad Kamil

    2016-01-01

    Full Text Available In recent years, the effect of overinflated tyre pressure and increased heavy vehicles’ axle load on flexible pavements has become a subject of great concern because of the higher stress levels induced and damage caused to road pavements. This paper aims to evaluate the effect of variable tyre inflation pressures (using actual tyre contact/footprint area to determine the responses of flexible pavement. A full scale experiment was conducted on a heavy vehicle with 1:1:2 axle configuration, 10 R 20 tyre size and attached trailer with constant axle load. Measurements were made for actual tyre-pavement contact area. KENPAVE linear elastic program was then used to analyse the effects of the measured actual tyre-pavement contact area and the results was compared using conventional circular tyre contact area. A comparative analysis was then made between the actual contact area and the conventional circular tyre contact area. It was found that high tyre inflation pressure produce smaller contact area, giving more detrimental effect on the flexible pavement. It was also found that the temperature of tyres when the heavy vehicles are operational give less significant impact on tyre inflation pressure for the Malaysian climate.

  1. Direct Observation of Heavy-Tailed Storage Times of Bed Load Tracer Particles Causing Anomalous Superdiffusion

    Science.gov (United States)

    Bradley, D. Nathan

    2017-12-01

    A consensus has formed that the step length distribution of fluvial bed load is thin tailed and that the observed anomalous superdiffusion of bed load tracer particles must arise from heavy-tailed resting times. However, heavy-tailed resting times have never been directly observed in the field over multiple floods. Using 9 years of data from a large bed load tracer experiment, I show that the spatial variance of the tracer plume scales faster than linearly with integrated excess stream power, indicating anomalous superdiffusion. The superdiffusion is caused by a heavy-tailed distribution of observed storage times that is fit with a truncated Pareto distribution with a tail parameter that is predicted by anomalous diffusion theory. The heavy-tailed distribution of storage times causes the tracer virtual velocity to slow over time, indicated by a sublinear increase in the mean displacement that is predicted by the storage time distribution tail parameter.

  2. Load equivalency factors (LEFs) for abnormal vehicles (AVs) and mobile cranes in South Africa based on the mechanistic-empirical (M-E) design methodology

    CSIR Research Space (South Africa)

    De Beer, Morris

    2009-07-01

    Full Text Available layer life of pavement under the loading of Axle of vehicle in question. v n ii=1 Total Additional Damage of Vehicle = TAD (Ncritical from Standard 80 kN/520 kPa Axle) (Ncritical from Legal 88 kN/700 kPa Axle) -(Ncritical from Axle...

  3. The Receptor Tyrosine Kinase AXL in Cancer Progression

    Directory of Open Access Journals (Sweden)

    Erinn B. Rankin

    2016-11-01

    Full Text Available The AXL receptor tyrosine kinase (AXL has emerged as a promising therapeutic target for cancer therapy. Recent studies have revealed a central role of AXL signaling in tumor proliferation, survival, stem cell phenotype, metastasis, and resistance to cancer therapy. Moreover, AXL is expressed within cellular components of the tumor microenvironment where AXL signaling contributes to the immunosuppressive and protumorigenic phenotypes. A variety of AXL inhibitors have been developed and are efficacious in preclinical studies. These agents offer new opportunities for therapeutic intervention in the prevention and treatment of advanced disease. Here we review the literature that has illuminated the cellular and molecular mechanisms by which AXL signaling promotes tumor progression and we will discuss the therapeutic potential of AXL inhibition for cancer therapy.

  4. Heavy metal transport in large river systems: heavy metal emissions and loads in the Rhine and Elbe river basins

    Science.gov (United States)

    Vink, Rona; Behrendt, Horst

    2002-11-01

    Pollutant transport and management in the Rhine and Elbe basins is still of international concern, since certain target levels set by the international committees for protection of both rivers have not been reached. The analysis of the chain of emissions of point and diffuse sources to river loads will provide policy makers with a tool for effective management of river basins. The analysis of large river basins such as the Elbe and Rhine requires information on the spatial and temporal characteristics of both emissions and physical information of the entire river basin. In this paper, an analysis has been made of heavy metal emissions from various point and diffuse sources in the Rhine and Elbe drainage areas. Different point and diffuse pathways are considered in the model, such as inputs from industry, wastewater treatment plants, urban areas, erosion, groundwater, atmospheric deposition, tile drainage, and runoff. In most cases the measured heavy metal loads at monitoring stations are lower than the sum of the heavy metal emissions. This behaviour in large river systems can largely be explained by retention processes (e.g. sedimentation) and is dependent on the specific runoff of a catchment. Independent of the method used to estimate emissions, the source apportionment analysis of observed loads was used to determine the share of point and diffuse sources in the heavy metal load at a monitoring station by establishing a discharge dependency. The results from both the emission analysis and the source apportionment analysis of observed loads were compared and gave similar results. Between 51% (for Hg) and 74% (for Pb) of the total transport in the Elbe basin is supplied by inputs from diffuse sources. In the Rhine basin diffuse source inputs dominate the total transport and deliver more than 70% of the total transport. The diffuse hydrological pathways with the highest share are erosion and urban areas.

  5. Immunomodulatory effect of ganoderma lucidum polysaccharides (GLP) on long-term heavy-load exercising mice.

    Science.gov (United States)

    Shi, Yali; Cai, Dehua; Wang, Xiaojie; Liu, Xinshen

    2012-12-01

    Long-term heavy-load exercise can lead to a decrease in the organism's immune response. In this study, we used 100 Kunming (KM) mice to investigate the immune-regulatory effects of Ganoderma lucidum polysaccharides (GLP) on long-term heavy-load exercising mice. Peripheral white blood cells (WBC), the absolute value of neutrophils (NEUT), the phagocytic function of macrophages, serum agglutination valence, and the number of plaque-forming cells (PFC) were evaluated 4 weeks after gavaging long-term heavy-load exercising mice with GLP. After exercise, the WBC count in peripheral blood, absolute neutrophil count, macrophage phagocytic index, serum agglutination valence, and the number of plaque-forming cells were significantly reduced in the mice not fed GLP. Both medium and high doses of GLP drastically increased peripheral WBC, absolute neutrophil count, macrophage phagocytic index, serum agglutination valence, and the number of plaque-forming cells in long-term heavy-load exercising mice. High doses of GLP increased peritoneal macrophage phagocytic rate considerably. With this study, we demonstrate that 4 weeks of heavy-load exercise can lead to exercise-induced immunosuppression in mice. A supplement of GLP fed to these mice improves both non-specific and specific immune responses among these mice. The effect for the high-dose GLP treatment is especially significant.

  6. EDGA amendment of slightly heavy metal loaded soil affects heavy metal solubility, crop growth and microbivorous nematodes but not bacteria and herbivorous nematodes

    NARCIS (Netherlands)

    Bouwman, L.A.; Bloem, J.; Römkens, P.F.A.M.; Japenga, J.

    2005-01-01

    Phytoextraction of heavy metals is a promising technology to remediate slightly and moderately contaminated soils. To enhance crops' uptake of heavy metals, chelates such as EDGA are being tested as soil additives. Heavy metal loaded EDGA can affect soil organisms such as bacteria and nematodes in

  7. Overload protection: avoidance response to heavy plantar surface loading.

    Science.gov (United States)

    Robbins, S E; Hanna, A M; Gouw, G J

    1988-02-01

    Current footwear which are designed for use in running are examples of intentional biomechanical model integration into device design. The inadequacy of this footwear in protecting against injury is postulated to be due to fixation on inadequate models of locomotory biomechanics that do not provide for feedback control; in particular, an hypothesized plantar surface sensory-mediated feedback control system, which imparts overload protection during locomotion. A heuristic approach was used to identify the hypothesized system. A random series of loads (0 to 164 kg) was applied to the knee flexed at 90 degrees. In this testing system, plantar surface avoidance behavior was the difference between the sum of the leg weight and the load applied to the knee, and the load measured at the plantar surface; this was produced by activation of hip flexors. Significant avoidance behavior was found in all of the subjects (P less than 0.001). On all surfaces tested, including modern athletic footwear (P less than 0.001), its magnitude increased directly in relation to the load applied to the knee (P less than 0.001). There were significant differences in avoidance behavior in relation to the weight-bearing surfaces tested (P less than 0.05). With the identification of a feedback control system which would serve to moderate loading during locomotion, an explanation is provided as to why current athletic footwear do not protect and may be injurious; thus allowing the design of footwear which may be truly protective.

  8. Dynamic modelling of heavy metals - time scales and target loads

    NARCIS (Netherlands)

    Posch, M.; Vries, de W.

    2009-01-01

    Over the past decade steady-state methods have been developed to assess critical loads of metals avoiding long-term risks in view of food quality and eco-toxicological effects on organisms in soils and surface waters. However, dynamic models are needed to estimate the times involved in attaining a

  9. EVALUATION OF DYNAMIC INDICATORS OF SIX-AXLE LOCOMOTIVE

    Directory of Open Access Journals (Sweden)

    S. V. Myamlin

    2015-04-01

    Full Text Available Purpose. The paper is devoted to dynamic characteristics evaluation of the locomotive with prospective design and determination the feasibility of its use on the Ukrainian railways. Methodology. The methods of mathematical and computer modeling of the dynamics of railway vehicles, as well as methods for the numerical integration of systems of ordinary nonlinear differential equations were used to solve the problem. Findings. The calculated diagram of a locomotive on three-axle bogies was built to solve the problem, and it is a system of rigid bodies connected by various elements of rheology. The mathematical model of the locomotive movement, allowing studying its spatial vibrations at driving on straight and curved sections of the track with random irregularities in plan and profile was developed with use of this calculated diagram. At compiling the mathematical model took into account both geometric (nonlinearity profile of the wheel roll surface and physical nonlinearity of the system (the work forces of dry friction, nonlinearity characteristics of interaction forces between wheels and rails. The multivariate calculations, which allowed assessing the dynamic qualities of the locomotive at its movement along straight and curved sections of the track, were realized with the use of computer modeling. The smoothness movement indicators of the locomotive in horizontal and vertical planes, frame strength, coefficients of vertical dynamics in the first and second stages of the suspension, the load factor of resistance against the derailment of the wheel from the rail were determined at the period of research. In addition, a comparison of the obtained results with similar characteristics is widely used on the Ukrainian railways in six-axle locomotive TE 116. The influence of speed and technical state of the track on the locomotive traffic safety was determined.Originality. A mathematical model of the spatial movement of a six-axle locomotive with

  10. ENHANCEMENT OF DURABILITY OF TRACTOR SUSPENSION AXLES

    Directory of Open Access Journals (Sweden)

    I. Doshchechkina

    2017-12-01

    Full Text Available The ‘soft’ nitriding of the suspension axle surface of the T150K tractor at the depth of 0.08 mm enables us to enhance its constructive strength, to increase its service life by 25 % and have a considerable economic effect.

  11. Flood deposits and their heavy metal load - example of the Neckar river

    International Nuclear Information System (INIS)

    Hellmann, H.

    1993-01-01

    Flood deposits may develop from suspended solids under certain conditions, e.g. after the passage of a flood wave. Depending on the origin of the suspended material, the heavy metal load in these deposits varies considerably. Recent sediments deposited in the Neckar waterway after the flood of February/March 1990 are taken as an example to explain that it is necessary to consider the contamination load in relation to the grain size of the material. To this end, the heavy metal contents of the fine grain fraction (grain diameter [de

  12. Dynamic response of the high flux isotope reactor structure caused by nearby heavy load drop

    International Nuclear Information System (INIS)

    Chang, Shih-Jung.

    1995-01-01

    A heavy load of 50,000 lb is assumed to drop from 10 ft above the bottom of the High Flux Isotope Reactor (HFIR) pool at the loading station. The consequences of the dynamic impact to the bottom slab of the pool and to the nearby HFIR reactor vessel are analyzed by applying the ABAQUS computer code The results show that both the BM vessel structure and its supporting legs are subjected to elastic disturbances only and, therefore, will not be damaged. The bottom slab of the pool, however, will be damaged to about half of the slab thickness. The velocity response spectrum at the concrete floor next to the HFIR vessel as a result of the vibration caused by the impact is obtained. It is concluded, that the damage caused by heavy load drop at the loading station is controlled by the slab damage and the nearby HFIR vessel and the supporting legs will not be damaged

  13. Design of the PE-3 hot heavy oil loading line

    Energy Technology Data Exchange (ETDEWEB)

    Mayants, Alex; Lanan, Glenn; Janardhanan, K. [INTEC Engineering, Houston, TX (United States); Gomes, Marcelino; Garcia, Amaury [TRANSPETRO - PETROBRAS Transportes, Rio de Janeiro, RJ (Brazil)

    2003-07-01

    The leaking of the PE-2 pipeline into Guanabara Bay. Rio de Janeiro, during late 2000 attracted widespread attention in Brazil and around the world. The safe design and operation of pipelines transporting hot, heavy hydrocarbons is critical for avoiding future oil spills. Conventional methods for designing pipelines that transport hot products rely on soil overburden to control upheaval buckling. However, extremely poor soil strength, combined with sediment mobility, led to the failure of the PE-2 pipeline. The serious consequences led TRANSPETRO to specify that the highest standards (DNV Safety Class High) were to be applied to the design and fabrication of the replacement PE-3 pipeline. The design was also required to withstand a large number of operational cycles, i.e. three (3) hot to cold cycles per week for the entire 40 years of the pipeline's design life. To meet these design challenges, several pipeline configurations were examined. A unique zigzag configuration was selected for this pipeline project. (author)

  14. Heavy vehicle pitch dynamics and suspension tuning

    OpenAIRE

    Cao, Dongpu; Rakheja, Subhash; Su, Chun-Yi

    2008-01-01

    The influence of suspension tuning of passenger cars on bounce and pitch ride performance has been explored in a number of studies, while only minimal efforts have been made for establishing similar rules for heavy vehicles. This study aims to explore pitch dynamics and suspension tunings of a two-axle heavy vehicle with unconnected suspension, which could also provide valuable information for heavy vehicles with coupled suspensions. Based on a generalised pitch-plane model of a two-axle heav...

  15. Application of eddy currents to the inspection of fatigue-corroded railway axles

    International Nuclear Information System (INIS)

    Carboni, Michele

    2012-01-01

    Recent experience with existing railway axles indicates that even when they are operated within the design loads, failure can happen due to the synergetic effect of both corrosion and cyclic loads. This synergy is not yet thoroughly understood, however a need for detecting corrosion-fatigue during service is mandatory. In the present paper, corrosion-fatigue tests are carried out, in the lab, on small-scale specimens in order to investigate the possibility to apply eddy currents non-destructive inspection to the detection of corrosion pits and corrosion-fatigue cracks during the service of railway axles. The obtained results are also supported by suitable numerical simulations carried out by a dedicated software package. Part of the presented results were obtained in the frame of the international research project RSSB T728 (just concluded) and the European research project WOLAXIM (still in progress).

  16. Single-axle, double-axis solar tracker

    Science.gov (United States)

    Brantley, L. W.; Lawson, B. D.

    1979-01-01

    Solar concentrator tracking mechanism consisting of angular axle and two synchronized drive motors, follows seasonal as well as diurnal changes in earth's orientation with respect to incoming sunlight.

  17. Pollution load index for heavy metals in Mian-Ab plain soil, Khuzestan, Iran.

    Science.gov (United States)

    Jorfi, Sahand; Maleki, Rohangiz; Jaafarzadeh, Neemat; Ahmadi, Mehdi

    2017-12-01

    Soil pollution by heavy metals is a major concern in agricultural area. Potential impact of heavy metals in agricultural soil on human health by accumulating in food chain demonstrated elsewhere. In this regard Mian-Ab plain as a major agricultural site of Khuzestan province considered for Arsenic, cadmium and lead concentration as the main potential toxic pollutants in soil. 50 topsoil samples were collected and analyzed by inductively coupled plasma mass spectrometry (ICP-MS). Also Contamination level of selected heavy metals in Mian-Ab Plain, was assessed by single factor contaminant index (PI) and pollution load index (PLI). Results show mean concentration of arsenic, cadmium and lead were 2.52, 0.30 and 7.21 mg kg -1 . Base on PLI results 12 point (24%) of the studied area show moderately polluted and 38 point (76%) show unpolluted area.

  18. Pneumatic control system for rapid vertical rectangular movements of heavy loads

    Energy Technology Data Exchange (ETDEWEB)

    Huettel, G; Krause, H [Zentralinstitut fuer Kernforschung, Rossendorf bei Dresden (German Democratic Republic)

    1975-01-01

    A new control system has been developed in order to realize the physically necessary short transition times between the dead points of a pneumatic oscillator even for heavy loads and high working speeds. Integral element of this system is the external control of braking process provided for in addition to the end position brake installed in the working cylinder. This control system is applicable not only to pile oscillators, but also universally applicable to pneumatic apparatuses.

  19. A pneumatic control system for rapid vertical rectangular movements of heavy loads

    International Nuclear Information System (INIS)

    Huettel, G.; Krause, H.

    1975-01-01

    A new control system has been developed in order to realize the physically necessary short transition times between the dead points of a pneumatic oscillator even for heavy loads and high working speeds. Integral element of this system is the external control of braking process provided for in addition to the end position brake installed in the working cylinder. This control system is applicable not only to pile oscillators, but also universally applicable to pneumatic apparatuses working like that. (author)

  20. [Magnetic Response of Dust-loaded Leaves in Parks of Shanghai to Atmospheric Heavy Metal Pollution].

    Science.gov (United States)

    Liu, Fei; Chu, Hui-min; Zheng, Xiang-min

    2015-12-01

    To reveal the magnetic response to the atmospheric heavy metal pollution in leaves along urban parks, Camphor leaf samples, widely distributed at urban parks, were collected along the year leading wind direction of Shanghai, by setting two vertical and horizontal sections, using rock magnetic properties and heavy metal contents analysis. The results showed that the magnetic minerals of samples were predominated by ferromagnetic minerals, and both the concentration and grain size of magnetite particles gradually decreased with the winter monsoon direction from the main industrial district. A rigorous cleaning of leaves using ultrasonic agitator washer could remove about 63%-90% of low-field susceptibility values of the leaves, and this strongly indicated that the intensity of magnetic signal was mainly controlled by the PMs accumulated on the leaves surfaces. Moreover, there was a significant linear relationship between heavy metals contents (Fe, Mn, Zn, Cu, Cr, V and Pb) and magnetic parameters (0.442 ≤ R ≤ 0.799, P atmospheric heavy metal pollution. The results of multivariate statistical analysis showed that the content of magnetic minerals and heavy metal indust-loaded tree leaves was affected by associated pollution of industry and traffic.

  1. Heavy vehicle simulator (HVS) evaluation of load transfer efficiency and continuously reinforced concrete inlays on the N3 near Pietermartizburg

    CSIR Research Space (South Africa)

    Du Plessis, L

    2006-07-01

    Full Text Available The paper addresses two different heavy Vehicle Simulator (HVS) studies conducted on concrete: Load transfer through aggregate interlock and the use of dowels and the evaluation of the performance of an in-service continuously reinforced concrete...

  2. Large stone asphalt mix design for heavy duty asphalt pavements

    CSIR Research Space (South Africa)

    Rust, FC

    1990-08-01

    Full Text Available The recent increase in traffic volumes and also axle loads on some of the major routes in South Africa has extended the traffic classes beyond the current highest design class. Additionally there is a strong lobby to increase the legal axle load...

  3. Influence of carrying heavy loads on soldiers' posture, movements and gait.

    Science.gov (United States)

    Attwells, Renee L; Birrell, Stewart A; Hooper, Robin H; Mansfield, Neil J

    2006-11-15

    Military personnel are required to carry heavy loads whilst marching; this load carriage represents a substantial component of training and combat. Studies in the literature mainly concentrate on physiological effects, with few biomechanical studies of military load carriage systems (LCS). This study examines changes in gait and posture caused by increasing load carriage in military LCS. The four conditions used during this study were control (including rifle, boots and helmet carriage, totalling 8 kg), webbing (weighing 8 kg), backpack (24 kg) and a light antitank weapon (LAW; 10 kg), resulting in an incremental increase in load carried from 8, 16, 40 to 50 kg. A total of 20 male soldiers were evaluated in the sagittal plane using a 3-D motion analysis system. Measurements of ankle, knee, femur, trunk and craniovertebral angles and spatiotemporal parameters were made during self-paced walking. Results showed spatiotemporal changes were unrelated to angular changes, perhaps a consequence of military training. Knee and femur ranges of motion (control, 21.1 degrees +/- 3.0 and 33.9 degrees +/- 7.1 respectively) increased (p < 0.05) with load (LAW, 25.5 degrees +/- 2.3 and 37.8 degrees +/- 1.5 respectively). The trunk flexed significantly further forward, confirming results from previous studies. In addition, the craniovertebral angle decreased (p < 0.001) indicating a more forward position of the head with load. It is concluded that the head functions in concert with the trunk to counterbalance load. The higher muscular tensions necessary to sustain these changes have been associated with injury, muscle strain and joint problems.

  4. Levitation or suspension: Which one is better for the heavy-load HTS maglev transportation

    Science.gov (United States)

    Liu, Wei; Kang, Dong; Yang, X. F.; Wang, Fei; Peng, G. H.; Zheng, Jun; Ma, G. T.; Wang, J. S.

    2015-09-01

    Because of the limitation of permanent magnet (PM), the efficient of bulk high-Tc superconductor (HTSC) in a high-Tc superconducting (HTS) maglev system is not very high. It is better to magnetize the bulk HTSC with a high trapped field to increase the force density. The different application type of magnetized bulk HTSC in a maglev system, namely, levitation or suspension type, will bring quite different operation performance. This paper discusses the influence of application type on operation performance of magnetized bulk HTSC by experiments and simulations. From the discussion, it can be found which application type is better for the heavy-load HTS maglev system.

  5. PROBABILISTIC FINITE ELEMENT ANALYSIS OF A HEAVY DUTY RADIATOR UNDER INTERNAL PRESSURE LOADING

    Directory of Open Access Journals (Sweden)

    ROBIN ROY P.

    2017-09-01

    Full Text Available Engine cooling is vital in keeping the engine at most efficient temperature for the different vehicle speed and operating road conditions. Radiator is one of the key components in the heavy duty engine cooling system. Heavy duty radiator is subjected to various kinds of loading such as pressure, thermal, vibration, internal erosion, external corrosion, creep. Pressure cycle durability is one of the most important characteristic in the design of heavy duty radiator. Current design methodologies involve design of heavy duty radiator using the nominal finite element approach which does not take into account of the variations occurring in the geometry, material and boundary condition, leading to over conservative and uneconomical designs of radiator system. A new approach is presented in the paper to integrate traditional linear finite element method and probabilistic approach to design a heavy duty radiator by including the uncertainty in the computational model. As a first step, nominal run is performed with input design variables and desired responses are extracted. A probabilistic finite elementanalysis is performed to identify the robust designs and validated for reliability. Probabilistic finite element includes the uncertainty of the material thickness, dimensional and geometrical variation. Gaussian distribution is employed to define the random variation and uncertainty. Monte Carlo method is used to generate the random design points.Output response distributions of the random design points are post-processed using different statistical and probability technique to find the robust design. The above approach of systematic virtual modelling and analysis of the data helps to find efficient and reliable robust design.

  6. Material Compressing Test of the High Polymer Part Used in Draft Gear of Heavy Load Locomotive

    Directory of Open Access Journals (Sweden)

    Wei Yangang

    2016-01-01

    Full Text Available According to the actual load cases of heavy load locomotive, the material compressing tests of the high polymer parts used in the locomotive are researched. The relationship between stress and strain during the material compressing are acquired by means of comparing the many results of the material compressing tests under different test condition. The relationship between stress and strain during the material compressing is nonlinear in large range of strain, but the relationship is approximately linear in small range of strain. The material of the high polymer made in China and the material of the high polymer imported are compared through the tests. The results show that the compressing property of the material of the high polymer made in China and the material of the high polymer imported are almost same. The research offers the foundation to study the structure elasticity of the draft gear.

  7. Differential Effects of Heavy Versus Moderate Loads on Measures of Strength and Hypertrophy in Resistance-Trained Men

    OpenAIRE

    Brad J. Schoenfeld, Bret Contreras, Andrew D. Vigotsky, Mark Peterson

    2016-01-01

    The purpose of the present study was to evaluate muscular adaptations between heavy- and moderate-load resistance training (RT) with all other variables controlled between conditions. Nineteen resistance-trained men were randomly assigned to either a strength-type RT routine (HEAVY) that trained in a loading range of 2-4 repetitions per set (n = 10) or a hypertrophy-type RT routine (MODERATE) that trained in a loading range of 8-12 repetitions per set (n = 9). Training was carried out 3 days ...

  8. Sobrecompactación del suelo agricola parte I: influencia diferencial del peso y del número de pasadas Overcompaction of agricultural soil part I: differential influence of axle load and number of passes

    Directory of Open Access Journals (Sweden)

    Daniel Jorajuria

    2000-12-01

    Full Text Available Han sido objetivos principales de este trabajo, tanto el discriminar la responsabilidad de las variables independientes, peso y número de pasadas, en la distribución vertical de la compactación inducida, como obtener evidencia que permita decidir la conveniencia entre conjuntos ligeros que rueden muchas veces sobre la superficie trabajada, o conjuntos más grandes y pesados que resuelvan la tarea con menos pasajes. Se trabajó sobre un suelo de textura fina, con alta humedad presente. Las variables experimentales independientes configuraron dos tratamientos, tractor pesado y ligero, y tres diferentes número de pasadas, 1, 5 y 10, resultaron en seis subtratamientos de diferente intensidad de tráfico, más una parcela testigo sin tráfico. Los resultados no mostraron diferencias entre los tratamientos pesado y ligero, en el rango más superficial evaluado, sin embargo siempre fueron muy significativas las diferencias si se considera el rango de mayor profundidad. Disminuciones del rendimiento del pastizal del orden de 7 a 25% fueron medidas en las zonas adyacentes a las huellas, mientras que esas pérdidas ascendieron al rango de 52 a 76% dentro de la impronta dejada por las huellas del tráfico. Se pudo concluir que, el número de pasadas reiteradas sobre la misma senda, puede emular, e incluso reemplazar, al factor peso sobre el eje, en la responsabilidad principal de inducir compactaciones en el subsuelo. Diez pasadas, es el número crítico de rodadas, a partir del cual se pierden las ventajas de traficar con un tractor ligero, como alternativa a uno pesado con menos pasadas.The main objectives of this research were: to determine the responsability of weight, number of passes and independent variables, on the vertical distribution of subsoil compaction and to obtain evidence to decide upon the convenience of matching equipments with light or heavy tractors, according to their differences in passes on the field. Field tests were carried

  9. Changes in muscle size and MHC composition in response to resistance exercise with heavy and light loading intensity

    DEFF Research Database (Denmark)

    Holm, L.; Reitelseder, S.; Pedersen, T.G.

    2008-01-01

    resonance imaging, muscle biopsies were obtained bilaterally from vastus lateralis for determination of myosin heavy chain (MHC) composition, and maximal muscle strength was assessed by 1RM testing and in an isokinetic dynamometer at 60 degrees /s. Quadriceps muscle cross-sectional area increased (P ...Muscle mass accretion is accomplished by heavy-load resistance training. The effect of light-load resistance exercise has been far more sparsely investigated with regard to potential effect on muscle size and contractile strength. We applied a resistance exercise protocol in which the same...... individual trained one leg at 70% of one-repetition maximum (1RM) (heavy load, HL) while training the other leg at 15.5% 1RM (light load, LL). Eleven sedentary men (age 25 +/- 1 yr) trained for 12 wk at three times/week. Before and after the intervention muscle hypertrophy was determined by magnetic...

  10. Differential Effects of Heavy Versus Moderate Loads on Measures of Strength and Hypertrophy in Resistance-Trained Men.

    Science.gov (United States)

    Schoenfeld, Brad J; Contreras, Bret; Vigotsky, Andrew D; Peterson, Mark

    2016-12-01

    The purpose of the present study was to evaluate muscular adaptations between heavy- and moderate-load resistance training (RT) with all other variables controlled between conditions. Nineteen resistance-trained men were randomly assigned to either a strength-type RT routine (HEAVY) that trained in a loading range of 2-4 repetitions per set (n = 10) or a hypertrophy-type RT routine (MODERATE) that trained in a loading range of 8-12 repetitions per set (n = 9). Training was carried out 3 days a week for 8 weeks. Both groups performed 3 sets of 7 exercises for the major muscle groups of the upper and lower body. Subjects were tested pre- and post-study for: 1 repetition maximum (RM) strength in the bench press and squat, upper body muscle endurance, and muscle thickness of the elbow flexors, elbow extensors, and lateral thigh. Results showed statistically greater increases in 1RM squat strength favoring HEAVY compared to MODERATE. Alternatively, statistically greater increases in lateral thigh muscle thickness were noted for MODERATE versus HEAVY. These findings indicate that heavy load training is superior for maximal strength goals while moderate load training is more suited to hypertrophy-related goals when an equal number of sets are performed between conditions.

  11. Differential Effects of Heavy Versus Moderate Loads on Measures of Strength and Hypertrophy in Resistance-Trained Men

    Directory of Open Access Journals (Sweden)

    Brad J. Schoenfeld, Bret Contreras, Andrew D. Vigotsky, Mark Peterson

    2016-12-01

    Full Text Available The purpose of the present study was to evaluate muscular adaptations between heavy- and moderate-load resistance training (RT with all other variables controlled between conditions. Nineteen resistance-trained men were randomly assigned to either a strength-type RT routine (HEAVY that trained in a loading range of 2-4 repetitions per set (n = 10 or a hypertrophy-type RT routine (MODERATE that trained in a loading range of 8-12 repetitions per set (n = 9. Training was carried out 3 days a week for 8 weeks. Both groups performed 3 sets of 7 exercises for the major muscle groups of the upper and lower body. Subjects were tested pre- and post-study for: 1 repetition maximum (RM strength in the bench press and squat, upper body muscle endurance, and muscle thickness of the elbow flexors, elbow extensors, and lateral thigh. Results showed statistically greater increases in 1RM squat strength favoring HEAVY compared to MODERATE. Alternatively, statistically greater increases in lateral thigh muscle thickness were noted for MODERATE versus HEAVY. These findings indicate that heavy load training is superior for maximal strength goals while moderate load training is more suited to hypertrophy-related goals when an equal number of sets are performed between conditions.

  12. FRONT AXLE OF MERCEDES AMG GT. MODELLING IN AUTODESK INVENTOR

    Directory of Open Access Journals (Sweden)

    COROLENCU Eduard – Narcis

    2017-05-01

    Full Text Available This paper analyzes the front axle of the Mercedes AMG GT model, as so as the graphical representation of the axle and of the subassemblies of suspension system and steering system, using the AutoCAD and Autodesk Inventor software. The paper include the steps for made the 3D model of the front axle in order to highlight the advantages of suspension and steering system, the function of this systems and methods for manufacturing of these. The 3D model presents a suite of complex surfaces. This type of surfaces is often designed with non-analytical means. The main commands and options used in Autodesk Inventor software were presented and explained. All the component parts of the front axle were modelled and assembled according to their functional role. Finally, the models were rendered in order to have a realistic appearance.

  13. Acute Effects of Elastic Bands on Kinetic Characteristics During the Deadlift at Moderate and Heavy Loads.

    Science.gov (United States)

    Galpin, Andrew J; Malyszek, Kylie K; Davis, Kyle A; Record, Shaina M; Brown, Lee E; Coburn, Jared W; Harmon, RoQue A; Steele, Jeff M; Manolovitz, Adam D

    2015-12-01

    Loading a barbell with variable resistance positively alters kinetic characteristics during the back squat and bench press but has never been studied during the deadlift. The purpose of this project was to examine the acute effects of combining elastic bands and free weights during the deadlift at moderate and heavy loads. Twelve trained men (age: 24.08 ± 2.35 years, height: 175.94 ± 5.38 cm, mass: 85.58 ± 12.49 kg, deadlift 1 repetition maximum (RM): 188.64 ± 16.13 kg) completed 2 variable resistance (B1 and B2) and 1 traditional free-weight (NB) condition at both 60 and 85% 1RM on a force plate. B1 had 15% resistance from bands, with the remaining 85% from free weights. B2 had 35% bands and 65% free weights. NB used free weights only. Average resistance was equated for all conditions. Power and velocity generally increased, whereas force decreased with the addition of bands. The amount of band tension (B1 or B2) had little impact on power when lifting at 60% 1RM. However, greater resistance from bands resulted in greater peak and relative power when lifting at 85% 1RM. Adding elastic bands decreased time to peak force (PF), time between PF and peak power (PP), and time between PF and peak velocity (PV) when compared with NB at 60% 1RM (NB > B1 > B2). These differences only reached significance for NB > B2 when lifting at 85% 1RM. These same differences existed for time between PP and PV. Thus, the amount of tension from bands has less impact on interpeak variables at heavier absolute loads. Practitioners should consider using heavy bands when prescribing the deadlift for speed or power, but not maximal force.

  14. Detection of failures of axle-bearings of railway vehicles

    Directory of Open Access Journals (Sweden)

    Bižić Milan B.

    2016-01-01

    Full Text Available The failure of axle-bearing is one of the most common causes of derailments of railway vehicles which are usually accompanied by huge material damage and human casualties. Modern railways are working intensively on the development and implementation of appropriate systems for early detection of axlebearing malfunctions, which are typically manifested by increasing of its temperature. The most common approach is based on the use of wayside systems or checkpoints located in certain places along the track. There is also an innovative approach that involves using the system for continuous measuring and online monitoring of axle-boxes temperature. The main aim is to provide early detection of malfunctions of the axle-bearing and prevention of the potential derailment. This paper analyses the existing solutions for the detection of axle-bearings malfunctions with special emphasis on the working principle and the main advantages and disadvantages. The paper presents the basics of the one newly developed wireless measuring system for on-line monitoring of axle-boxes temperature. The measuring system was tested in real conditions and can be successfully applied to the commercial railway vehicles. The main conclusion is that systems for on-line monitoring of axle-bearings temperatures are far more efficient than wayside systems. Obtained results may be important for those who deal with these and similar problems, problems of development, exploitation and maintenance of railway vehicles, strategies, regulations, etc.

  15. Study on control schemes of flexible steering system of a multi-axle all-wheel-steering robot

    Directory of Open Access Journals (Sweden)

    Pingxia Zhang

    2016-05-01

    Full Text Available It is well known that a multi-axle wheeled robot possesses larger load capability and also higher drive performance. However, its steering flexibility is degraded due to the large number of wheels. In order to solve this problem, in this article, we proposed three control schemes based on the center of rotation or the steering angles of both the first- and last-axle wheels. To release these control schemes, steering mode selection and also the left wheel’s steering angle in a specific axle are added approaching a practical application. Thereafter, the remaining wheels’ steering angles can be calculated with the Ackerman steering theorem. In order to verify the control effects, a five-axle all-wheel-steering wheeled robot has been developed with the Bluetooth wireless monitor system. Based on the newly designed robot, validation experiments are carried out, such as lateral movement, situ rotation, and multi-mode steering within a narrow space. The results indicate that the proposed design in this article can ensure a more flexible and faster movement within a narrow space. It shows large potential in obstacle avoidance compared with the conventional partial-wheel steering mode.

  16. Advanced interlocking systems to improve heavy-load-bearing characteristics of flexible intramedullary nailing

    Energy Technology Data Exchange (ETDEWEB)

    Berger, Leopold, E-mail: leopold.berger@tuwien.ac.at [Institute of Building Construction and Technology, TU Wien, Karlsplatz 13/206-4, 1040 Vienna (Austria); Eichler, Johannes [Department of Orthopedics and Orthopedic Surgery, Medical University of Graz, Auenbruggerplatz 5/6, 8036 Graz (Austria); Ryll, E. Jonathan S. [Department of Trauma-, Hand- and Reconstructive Surgery, University Hospital Muenster, Westphalian-Wilhelms University, Muenster (Germany); Fischerauer, Stefan [Department of Traumatology, Medical University of Graz, Auenbruggerplatz 5/6, 8036 Graz (Austria); Raschke, Michael J. [Department of Trauma-, Hand- and Reconstructive Surgery, University Hospital Muenster, Westphalian-Wilhelms University, Muenster (Germany); Kolbitsch, Andreas [Institute of Building Construction and Technology, TU Wien, Karlsplatz 13/206-4, 1040 Vienna (Austria); Castellani, Christoph [Department of Pediatric and Adolescence Surgery, Medical University of Graz, Auenbruggerplatz 34, 8036 Graz (Austria); Weinberg, Annelie-Martina [Department of Orthopedics and Orthopedic Surgery, Medical University of Graz, Auenbruggerplatz 5/6, 8036 Graz (Austria)

    2016-11-01

    Flexible intramedullary nailing (FIN) is a minimally invasive and widespread standard method for osteosynthesis of pediatric long bone fractures. In the case of unstable fractures of the lower extremity, interlocking systems need to be used to prevent axial shortening and subsequent perforation of the nail at its insertion site. In the present study, four different screw-fixed interlocking systems for FINs (Hofer TwinPlug with two 3-mm titanium interlocking screws, Hofer FixPlug with 3-mm titanium interlocking screw, Hofer Plug with 3.5-mm titanium interlocking screw, and Hofer Plug with 3-mm titanium interlocking screw) in comparison with the commonly used Ender stainless steel nails (locked with 3.5-mm screw) were experimentally investigated in cadaveric lamb tibiae, regarding their load characteristics and failure modes in the case of heavy loading. The specimens were subjected to sequential axial cyclic loading of 5000cycles with stepwise increase of the load amplitude until failure. Migration of locking screws and internal damage of bone tissue was quantified by micro-computed tomography (CT) imaging. Ender nails failed on average at a peak load of 800 N, TwinPlugs at 1367 N, FixPlugs at 1222 N, Plugs 3.5mm at 1225 N and Plugs 3.0mm at 971 N. TwinPlugs, FixPlugs, and Plugs 3.5mm failed in a slow manner over several hundred loading cycles, whereas Ender nails and Plugs 3.0mm exhibited abrupt failure without any prior indication. Our results confirm that axial stability of FIN can be further improved by screw-fixed plugs by simultaneously avoiding shortcomings of an eye-locked system, which the Ender nails are. Considering biomechanical results, plug interlocking systems with 3.5-mm screws should be favored over conventional Ender nails and plugs with 3-mm screws. - Highlights: • Locked flexible intramedullary nails in lamb tibiae were cyclically loaded. • Strongly different failure modes of locking systems were detected. • Novel screw-fixed plugs are

  17. Event-based scenario manager for multibody dynamics simulation of heavy load lifting operations in shipyards

    Directory of Open Access Journals (Sweden)

    Sol Ha

    2016-01-01

    Full Text Available This paper suggests an event-based scenario manager capable of creating and editing a scenario for shipbuilding process simulation based on multibody dynamics. To configure various situation in shipyards and easily connect with multibody dynamics, the proposed method has two main concepts: an Actor and an Action List. The Actor represents the anatomic unit of action in the multibody dynamics and can be connected to a specific component of the dynamics kernel such as the body and joint. The user can make a scenario up by combining the actors. The Action List contains information for arranging and executing the actors. Since the shipbuilding process is a kind of event-based sequence, all simulation models were configured using Discrete EVent System Specification (DEVS formalism. The proposed method was applied to simulations of various operations in shipyards such as lifting and erection of a block and heavy load lifting operation using multiple cranes.

  18. Design of the Driving and Clamp Rotation Hydraulic Control System for the Heavy Load Forging Manipulator

    Directory of Open Access Journals (Sweden)

    Li Geqiang

    2015-01-01

    Full Text Available The manipulator was equipped with full hydraulic drive. We designed the hydraulic systems for the driving and clamping rotation. We used a fuzzy PID control strategy to design the electro-hydraulic proportional control system. We built a united simulation model based on the co-simulation of MATLAB/Simulink and AMEsim. A mathematical model of the system was also established. We did separate simulations of the system’s dynamic characteristics for fast forging and normal forging working conditions. The parameters were optimized. The field test shows that the steady-state error of the hydraulic system is small and the system response is fast. The system’s rapid response speed, high precision, and stability under heavy load were realized.

  19. Heavy metal and microbial loads in sewage irrigated vegetables of Kabul, Afghanistan

    Directory of Open Access Journals (Sweden)

    Andreas Buerkert

    2011-06-01

    Full Text Available Little is known about the heavy metal and microbial contamination of vegetables produced in Central Asian cities. We therefore measured the concentration of cadmium (Cd, copper (Cu, lead (Pb, and zinc (Zn and of faecal pathogens (Coliform bacteria, Salmonella sp., Shigella sp., Ascaris lubricoides, Entamoeba sp. and pinworms [Oxyuris vermicularis syn. Enterobius vermicularis] in soil, irrigation water, and marketed vegetables of Kabul City, Afghanistan. Leaf Pb and Zn concentrations of leafy vegetables were with 1–5 and 33–160 mg kg^{-1} dry weight (DW several-fold above respective international thresholds of 0.3 mg Pb kg^{-1} and 50 mg Zn kg^{-1}. The tissue concentration of Cu was below threshold limits in all samples except for spinach in one farm. Above-threshold loads of microbes and parasites on vegetables were found in five out of six gardens with coliforms ranging from 0.5–2 × 10^7 cells 100g^{-1} fresh weight (FW, but no Salmonella and Shigella were found. Contamination with 0.2 × 10^7 eggs 100g^{-1} FW of Ascaris was detected on produce of three farms and critical concentrations of Entamoeba in a single case, while Oxyuris vermicularis, and Enterobius vermicularis were found on produce of three and four farms, respectively. Irrigation water had Ascaris, Coliforms, Salmonella, Shigella, Entamoeba, and Oxyuris vermicularis syn. Enterobius vermicularis ranging from 0.35 × 10^7 to 2 × 10^7 cells l^{-1}. The heavy metal and microbial loads on fresh UPA vegetables are likely the result of contamination from rising traffic, residues of the past decades of war and lacking treatment of sewage which needs urgent attention.

  20. Acute effects of heavy-load squats on consecutive squat jump performance.

    Science.gov (United States)

    Weber, Kurt R; Brown, Lee E; Coburn, Jared W; Zinder, Steven M

    2008-05-01

    Postactivation potentiation (PAP) and complex training have generated interest within the strength and conditioning community in recent years, but much of the research to date has produced confounding results. The purpose of this study was to observe the acute effects of a heavy-load back squat [85% 1 repetition maximum (1RM)] condition on consecutive squat jump performance. Twelve in-season Division I male track-and-field athletes participated in two randomized testing conditions: a five-repetition back squat at 85% 1RM (BS) and a five-repetition squat jump (SJ). The BS condition consisted of seven consecutive squat jumps (BS-PRE), followed by five repetitions of the BS at 85% 1RM, followed by another set of seven consecutive squat jumps (BS-POST). The SJ condition was exactly the same as the BS condition except that five consecutive SJs replaced the five BSs, with 3 minutes' rest between each set. BS-PRE, BS-POST, SJ-PRE, and SJ-POST were analyzed and compared for mean and peak jump height, as well as mean and peak ground reaction force (GRF). The BS condition's mean and peak jump height and peak GRF increased 5.8% +/- 4.8%, 4.7% +/- 4.8%, and 4.6% +/- 7.4%, respectively, whereas the SJ condition's mean and peak jump height and peak GRF decreased 2.7% +/- 5.0%, 4.0% +/- 4.9%, and 1.3% +/- 7.5%, respectively. The results indicate that performing a heavy-load back squat before a set of consecutive SJs may enhance acute performance in average and peak jump height, as well as peak GRF.

  1. Interference of Heavy Aerosol Loading on the VIIRS Aerosol Optical Depth (AOD Retrieval Algorithm

    Directory of Open Access Journals (Sweden)

    Yang Wang

    2017-04-01

    Full Text Available Aerosol optical depth (AOD has been widely used in climate research, atmospheric environmental observations, and other applications. However, high AOD retrieval remains challenging over heavily polluted regions, such as the North China Plain (NCP. The Visible Infrared Imaging Radiometer Suite (VIIRS, which was designed as a successor to the Moderate Resolution Imaging Spectroradiometer (MODIS, will undertake the aerosol observations mission in the coming years. Using the VIIRS AOD retrieval algorithm as an example, we analyzed the influence of heavy aerosol loading through the 6SV radiative transfer model (RTM with a focus on three aspects: cloud masking, ephemeral water body tests, and data quality estimation. First, certain pixels were mistakenly screened out as clouds and ephemeral water bodies because of heavy aerosols, resulting in the loss of AOD retrievals. Second, the greenness of the surface could not be accurately identified by the top of atmosphere (TOA index, and the quality of the aggregation data may be artificially high. Thus, the AOD retrieval algorithm did not perform satisfactorily, indicated by the low availability of data coverage (at least 37.97% of all data records were missing according to ground-based observations and overestimation of the data quality (high-quality data increased from 63.42% to 80.97% according to radiative simulations. To resolve these problems, the implementation of a spatial variability cloud mask method and surficial index are suggested in order to improve the algorithm.

  2. A New Approach for Reliability Life Prediction of Rail Vehicle Axle by Considering Vibration Measurement

    Directory of Open Access Journals (Sweden)

    Meral Bayraktar

    2014-01-01

    Full Text Available The effect of vibration on the axle has been considered. Vibration measurements at different speeds have been performed on the axle of a running rail vehicle to figure out displacement, acceleration, time, and frequency response. Based on the experimental works, equivalent stress has been used to find out life of the axles for 90% and 10% reliability. Calculated life values of the rail vehicle axle have been compared with the real life data and it is found that the life of a vehicle axle taking into account the vibration effects is in good agreement with the real life of the axle.

  3. Soot particulate size characterisation in a heavy-duty diesel engine for different engine loads by laser-induced incandescence

    NARCIS (Netherlands)

    Bougie, B.; Ganippa, L.C.; Vliet, van A.P.; Meerts, W.L.; Dam, N.J.; Meulen, ter J.J.

    2007-01-01

    Time-resolved laser-induced incandescence was used to estimate primary particle size distributions inside the combustion chamber of a heavy-duty diesel engine as a function of the crank angle, for two different engine loads at two different probe locations. Assuming a log-normal particle size

  4. Omnidirectional configuration and control approach on mini heavy loaded forklift autonomous guided vehicle

    Directory of Open Access Journals (Sweden)

    Adam Norsharimie

    2017-01-01

    Full Text Available This paper presents the omnidirectional configuration and control approach on Mini Heavy Loaded Forklift Autonomous Guided Vehicle (MHeLFAGV for flexibility maneuverability in confine and narrow area. The issue in turning motion for nonholonomic vehicle in confine area becoming a motivation in MHeLFAGV design to provide holonomic vehicle with flexible movement. Therefore an omni-wheeled named Mecanum wheel has been configured in this vehicle design as well as omnidirectional control algorithm. MHeLFAGV system is developed with collaboration and inspired from Vacuumshmelze (M Sdn. Bhd. Pekan, Pahang in order to have a customized mini forklift that able to work in a very confined warehouse (170cm × 270cm square with heavy payload in a range of 20-200kg. In electronics control design, two stages of controller boards are developed namely as Board 1 and 2 that specifically for movement controller board and monitoring controller board respectively. In addition separate module of left, right, forward, backward, diagonal and zigzagging movement is developed as embedded modules for MHeLFAGV system’s control architecture. A few experiments are done to verify the algorithm for each omnidirectional movement of MHeLFAGV system in the wide area. The waypoint of MHeLFAGV movement is plotted using Global Positioning System (GPS as well as a digital compass by mapping the longitude and latitude of the vehicle. There are slightly different between the targeted movements with recorded data since Mecanum wheeled affected by the uneven surface of the landscape. The experiment is also further on moving in confine are on the actual targeted warehouse.

  5. Future residential loads profiles : scenario-based analysis of high penetration of heavy loads and distributed generation

    NARCIS (Netherlands)

    Asare-Bediako, B.; Kling, W.L.; Ribeiro, P.F.

    2014-01-01

    Electric load profiles are useful for accurate load forecasting, network planning and optimal generation capacity. They represent electricity demand patterns and are to a large extent predictable. However, new and heavier loads (heat pumps and electric vehicles), distributed generation, and home

  6. USING COUPLING WEIGHTS AND RATIONAL DISTRIBUTION OF BRAKE FORCES BETWEEN THE AXLES OF WHEELED VEHICLES

    Directory of Open Access Journals (Sweden)

    M. Kholodov

    2011-01-01

    Full Text Available The dependence of the coefficient of coupling weight-axle vehicles under braking and a ra-tional distribution coefficient of braking force to the front axle on the condition of maximum coupling weight.

  7. REFLOS, Fuel Loading and Cost from Burnup and Heavy Atomic Mass Flow Calculation in HWR

    International Nuclear Information System (INIS)

    Boettcher, W.; Schmidt, E.

    1969-01-01

    1 - Nature of physical problem solved: REFLOS is a programme for the evaluation of fuel-loading schemes in heavy water moderated reactors. The problems involved in this study are: a) Burn-up calculation for the reactor cell. b) Determination of reactivity behaviour, power distribution, attainable burn-up for both the running-in period and the equilibrium of a 3-dimensional heterogeneous reactor model; investigation of radial fuel movement schemes. c) Evaluation of mass flows of heavy atoms through the reactor and fuel cycle costs for the running-in, the equilibrium, and the shut down of a power reactor. If the subroutine for treating the reactor cell were replaced by a suitable routine, other reactors with weakly absorbing moderators could be analyzed. 2 - Method of solution: Nuclear constants and isotopic compositions of the different fuels in the reactor are calculated by the cell-burn-up programme and tabulated as functions of the burn-up rate (MWD/T). Starting from a known state of the reactor, the 3-dimensional heterogeneous reactor programme (applying an extension of the technique of Feinberg and Galanin) calculates reactivity and neutron flux distribution using one thermal and one or two fast neutron groups. After a given irradiation time, the new state of the reactor is determined, and new nuclear constants are assigned to the various defined locations in the reactor. Reloading of fuel may occur if the prescribed life of the reactor is reached or if the effective multiplication factor or the power form factor falls below a specified level. The scheme of reloading to be carried out is specified by a load vector, giving the number of channels to be discharged, the kind of movement from one to another channel and the type of fresh fuel to be charged for each single reloading event. After having determined the core states characterizing the equilibrium period, and having decided the fuel reloading scheme for the running-in period of the reactor life, the fuel

  8. Molecular mechanism of 17-allylamino-17-demethoxygeldanamycin (17-AAG)-induced AXL receptor tyrosine kinase degradation.

    Science.gov (United States)

    Krishnamoorthy, Gnana Prakasam; Guida, Teresa; Alfano, Luigi; Avilla, Elvira; Santoro, Massimo; Carlomagno, Francesca; Melillo, Rosa Marina

    2013-06-14

    The receptor tyrosine kinase AXL is overexpressed in many cancer types including thyroid carcinomas and has well established roles in tumor formation and progression. Proper folding, maturation, and activity of several oncogenic receptor tyrosine kinases require HSP90 chaperoning. HSP90 inhibition by the antibiotic geldanamycin or its derivative 17-allylamino-17-demethoxygeldanamycin (17-AAG) causes destabilization of its client proteins. Here we show that AXL is a novel client protein of HSP90. 17-AAG induced a time- and dose-dependent down-regulation of endogenous or ectopically expressed AXL protein, thereby inhibiting AXL-mediated signaling and biological activity. 17-AAG-induced AXL down-regulation specifically affected fully glycosylated mature receptor present on cell membrane. By using biotin and [(35)S]methionine labeling, we showed that 17-AAG caused depletion of membrane-localized AXL by mediating its degradation in the intracellular compartment, thus restricting its exposure on the cell surface. 17-AAG induced AXL polyubiquitination and subsequent proteasomal degradation; under basal conditions, AXL co-immunoprecipitated with HSP90. Upon 17-AAG treatment, AXL associated with the co-chaperone HSP70 and the ubiquitin E3 ligase carboxyl terminus of HSC70-interacting protein (CHIP). Overexpression of CHIP, but not of the inactive mutant CHIP K30A, induced accumulation of AXL polyubiquitinated species upon 17-AAG treatment. The sensitivity of AXL to 17-AAG required its intracellular domain because an AXL intracellular domain-deleted mutant was insensitive to the compound. Active AXL and kinase-dead AXL were similarly sensitive to 17-AAG, implying that 17-AAG sensitivity does not require receptor phosphorylation. Overall our data elucidate the molecular basis of AXL down-regulation by HSP90 inhibitors and suggest that HSP90 inhibition in anticancer therapy can exert its effect through inhibition of multiple kinases including AXL.

  9. Molecular Mechanism of 17-Allylamino-17-demethoxygeldanamycin (17-AAG)-induced AXL Receptor Tyrosine Kinase Degradation*

    Science.gov (United States)

    Krishnamoorthy, Gnana Prakasam; Guida, Teresa; Alfano, Luigi; Avilla, Elvira; Santoro, Massimo; Carlomagno, Francesca; Melillo, Rosa Marina

    2013-01-01

    The receptor tyrosine kinase AXL is overexpressed in many cancer types including thyroid carcinomas and has well established roles in tumor formation and progression. Proper folding, maturation, and activity of several oncogenic receptor tyrosine kinases require HSP90 chaperoning. HSP90 inhibition by the antibiotic geldanamycin or its derivative 17-allylamino-17-demethoxygeldanamycin (17-AAG) causes destabilization of its client proteins. Here we show that AXL is a novel client protein of HSP90. 17-AAG induced a time- and dose-dependent down-regulation of endogenous or ectopically expressed AXL protein, thereby inhibiting AXL-mediated signaling and biological activity. 17-AAG-induced AXL down-regulation specifically affected fully glycosylated mature receptor present on cell membrane. By using biotin and [35S]methionine labeling, we showed that 17-AAG caused depletion of membrane-localized AXL by mediating its degradation in the intracellular compartment, thus restricting its exposure on the cell surface. 17-AAG induced AXL polyubiquitination and subsequent proteasomal degradation; under basal conditions, AXL co-immunoprecipitated with HSP90. Upon 17-AAG treatment, AXL associated with the co-chaperone HSP70 and the ubiquitin E3 ligase carboxyl terminus of HSC70-interacting protein (CHIP). Overexpression of CHIP, but not of the inactive mutant CHIP K30A, induced accumulation of AXL polyubiquitinated species upon 17-AAG treatment. The sensitivity of AXL to 17-AAG required its intracellular domain because an AXL intracellular domain-deleted mutant was insensitive to the compound. Active AXL and kinase-dead AXL were similarly sensitive to 17-AAG, implying that 17-AAG sensitivity does not require receptor phosphorylation. Overall our data elucidate the molecular basis of AXL down-regulation by HSP90 inhibitors and suggest that HSP90 inhibition in anticancer therapy can exert its effect through inhibition of multiple kinases including AXL. PMID:23629654

  10. Eddy current system for inspection of train hollow axles

    Energy Technology Data Exchange (ETDEWEB)

    Chady, Tomasz; Psuj, Grzegorz; Sikora, Ryszard; Kowalczyk, Jacek; Spychalski, Ireneusz [Department of Electrical and Computer Engineering, Faculty of Electrical Engineering, West Pomeranian University of Technology, Szczecin (Poland)

    2014-02-18

    The structural integrity of wheelsets used in rolling stock is of great importance to the safety. In this paper, electromagnetic system with an eddy current transducer suitable for the inspection of hollow axles have been presented. The transducer was developed to detect surface braking defects having depth not smaller than 0.5 mm. Ultrasound technique can be utilized to inspect the whole axle, but it is not sufficiently sensitive to shallow defects located close to the surface. Therefore, the electromagnetic technique is proposed to detect surface breaking cracks that cannot be detected by ultrasonic technique.

  11. Optimization of Front Axle Suspension System of Articulated Dump Truck

    DEFF Research Database (Denmark)

    Langer, Thomas Heegaard; Christensen, Brian B.; Mouritsen, Ole Ø.

    2010-01-01

    that has been subjected to comfort improvement is a two axle articulated dump truck. The comfort has been in terms of whole body vibration exposure and the overall improvement has been made possible by adding front axle suspension. However, a hydraulic stabilizing system between the tractor and trailer...... to evaluate the whole body vibrations. By use of a multibody simulation model of the dump truck the whole body vibration exposure has been computed using the predefined work cycle as model input. The design parameters comprise the components of the hydraulic subsystem of the suspension, i.e., the size...

  12. Recommendations regarding higher axlemass limits for axles fitted with wide base tyres

    CSIR Research Space (South Africa)

    Roux, MP

    2011-01-01

    Full Text Available This paper presents the results of an investigation into possible higher axle mass limits for axles and axle units fitted with wide base tyres, i.e. tyres with nominal section widths of 385 mm, 425 mm and 445 mm, by comparing the road wear caused...

  13. Phosphorus-loaded biochar changes soil heavy metals availability and uptake potential of maize (Zea mays L.) plants.

    Science.gov (United States)

    Ahmad, Munir; Usman, Adel R A; Al-Faraj, Abdullah S; Ahmad, Mahtab; Sallam, Abdelazeem; Al-Wabel, Mohammad I

    2018-03-01

    Biochar (BC) was produced by pyrolyzing the date palm leaf waste at 600 °C and then loaded with phosphorus (P) via sorption process. Greenhouse pot experiment was conducted to investigate the application effects of BC and P-loaded biochar (BCP) on growth and availability of P and heavy metals to maize (Zea mays L.) plants grown in contaminated mining soil. The treatments consisted of BC and BCP (at application rates of 5, 10, 20, and 30 g kg -1 of soil), recommended NK and NPK, and a control (no amendment). Sorption experiment showed that Langmuir predicted maximum P sorption capacity of BC was 13.71 mg g -1 . Applying BCP increased the soil available P, while BC and BCP significantly decreased the soil labile heavy metals compared to control. Likewise, heavy metals in exchangeable and reducible fractions were transformed to more stable fraction with BC and BCP applications. The highest application rate of BCP (3%) was most effective treatment in enhancing plant growth parameters (shoot and root lengths and dry matter) and uptake of P and heavy metals by 2-3 folds. However, based on metal uptake and phytoextraction indices, total heavy metals extraction by maize plants was very small for practical application. It could be concluded that using P-loaded biochar as a soil additive may be considered a promising tool to immobilize heavy metals in contaminated mining areas, while positive effects on the biomass growth of plants may assist the stabilization of contaminated areas affected by wind and water erosion. Copyright © 2017 Elsevier Ltd. All rights reserved.

  14. Remote handling dynamical modelling: assessment on new approach to enhance positioning accuracy with heavy load manipulation

    International Nuclear Information System (INIS)

    Gagarina-Sasia, T.; David, O.; Dubus, G.; Perrot, Y.; Riwain, A.

    2007-01-01

    In vessel maintenance work in Fusion Tokamak will be carried out with help several sets of robotic devices. Heavy loads handling in constrained space is identified by all players of the RH community as a key-issue in the latest Fusion Tokamak facilities. To deal with high-level dexterity tasks, high payload to mass ratio and limited operating space, RH equipment designers can only propose systems whose mechanical flexibility is no longer negligible and need to be taken into account in the control scheme. Traditional approaches where control system only includes a linear model of deformation of the structure leads to poor positioning accuracy. Uncontrolled or under evaluated errors could be damaging for in-vessel components during maintenance operations in the Tokamak facility. To address the control of complex flexible systems, we will investigate the use of specific mechanical software that combines both finite element and kinematical joints analyses, with a strong-coupled formulation, to perform system dynamics simulations. This procedure will be applied on a single axis mock up robotic joint with highly flexible structure. A comparison of experimental results with the traditional linear approach and the specified software model will be carried out. Benefits introduced by this new approach will finally be assessed in view of RH design or specification in the field of RH in Fusion Tokamak scale such as ITER. (orig.)

  15. Throughput analysis of the IEEE 802.4 token bus standard under heavy load

    Science.gov (United States)

    Pang, Joseph; Tobagi, Fouad

    1987-01-01

    It has become clear in the last few years that there is a trend towards integrated digital services. Parallel to the development of public Integrated Services Digital Network (ISDN) is service integration in the local area (e.g., a campus, a building, an aircraft). The types of services to be integrated depend very much on the specific local environment. However, applications tend to generate data traffic belonging to one of two classes. According to IEEE 802.4 terminology, the first major class of traffic is termed synchronous, such as packetized voice and data generated from other applications with real-time constraints, and the second class is called asynchronous which includes most computer data traffic such as file transfer or facsimile. The IEEE 802.4 token bus protocol which was designed to support both synchronous and asynchronous traffic is examined. The protocol is basically a timer-controlled token bus access scheme. By a suitable choice of the design parameters, it can be shown that access delay is bounded for synchronous traffic. As well, the bandwidth allocated to asynchronous traffic can be controlled. A throughput analysis of the protocol under heavy load with constant channel occupation of synchronous traffic and constant token-passing times is presented.

  16. Detection of early squats by axle box acceleration

    NARCIS (Netherlands)

    Molodova, M.

    2013-01-01

    This thesis discusses a new method for detection of short track irregularities, particularly squats, with axle box acceleration (ABA) measurements. A squat is a surface initiated short track defect, associated with high frequency vibrations of the wheel-rail system. High stresses in the contact

  17. DACIA LOGAN LIVE AXLE OPTIMISATION USING COMPUTER GRAPHICS

    Directory of Open Access Journals (Sweden)

    KIRALY Andrei

    2017-05-01

    Full Text Available The paper presents some contributions to the calculus and optimisation of a live axle used at Dacia Logan using computer graphics software for creating the model and afterwards using FEA evaluation to determine the effectiveness of the optimisation. Thus using specialized computer software, a simulation is made and the results were compared to the measured real prototype.

  18. Control of heavy loads at nuclear power plants: Resolution of Generic Technical Activity A-36. Technical report

    International Nuclear Information System (INIS)

    George, H.J.

    1980-07-01

    This report summarizes work performed by the NRC staff in the resolution of Generic Technical Activity A-36, Control of Heavy Loads Near Spent Fuel. Generic Technical Activity A-36 is one of the generic technical subjects designated as unresolved safety issues pursuant to Section 210 of the Energy Reorganization Act of 1974. The report describes the technical studies and evaluations performed by the NRC staff, the staff's guidelines based on these studies, and the staff's plans for implementaton of its technical guidelines

  19. Dynamic analysis of rail vehicle axle

    Indian Academy of Sciences (India)

    In the study of Yagiz & Gursel (2005), the vertical and angular vibrations of the .... Figure 6. Variation of dynamic forces versus speed related to way conditions. ... analysed due to spring stiffness and railway quality and passenger coach load.

  20. LSTM-Based Temperature Prediction for Hot-Axles of Locomotives

    Directory of Open Access Journals (Sweden)

    Luo Can

    2017-01-01

    Full Text Available The reliability of locomotives plays a central role for the smooth operation of railway systems. Hot-axle failures are one of the most commonly found problems leading to locomotive accidents. Since the operating status of the locomotive axle bearings can be distinctly reflected by the axle temperatures, online temperature monitoring has become an essential way to detect hot-axle failures. In this work, we explore the feasibility of predict the hot-axle failures by identifying the temperature from predicted nominal values. We propose a data-driven approach based on the Long Short-Term Memory (LSTM network to predict the sensor temperature for axle bearings. The effectiveness of the prediction model was validated with operation data collected from commercial locomotives. With a prediction accuracy is within a few percent, the proposed techniques can be used as a dynamic reference for hot-axle monitoring.

  1. Inhibition of Axl improves the targeted therapy against ALK-mutated neuroblastoma

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Fei [Department of Neurology, Sichuan Medical Science Institute and Sichuan Provincial Hospital, Chengdu 610072 (China); Li, Hongling [Department of Radiotherapy, Shanghai First People’s Hospital, Shanghai Jiao Tong University, Shanghai 201620 (China); Sun, Yong, E-mail: sunfanqi2010@163.com [Department of Burn and Plastic Surgery, Huai’an First People’s Hospital, Nanjing Medical University, Huai’an 223300 (China)

    2014-11-28

    Highlights: • First reported Axl is co-expressed with ALK in neuroblastoma tissues and cell lines. • Axl activation promotes cell growth and impairs the efficiency of ALK inhibitor. • Further found silence of Axl leads to increased sensitivity to ALK inhibitors. • Axl inhibitor promotes the efficiency of targeted therapy in vitro and in vivo. • Axl activation should be considered in the clinical application of ALK inhibitors. - Abstract: Neuroblastoma (NB) patients harboring mutated ALK can be expected to potentially benefit from targeted therapy based on ALK tyrosine kinase inhibitor (TKI), such as crizotinib and ceritinib. However, the effect of the treatment varies with different individuals, although with the same genic changes. Axl receptor tyrosine kinase is expressed in a variety of human cancers, but little data are reported in NB, particularly in which carrying mutated ALK. In this study, we focus on the roles of Axl in ALK-mutated NB for investigating rational therapeutic strategy. We found that Axl is expressed in ALK-positive NB tissues and cell lines, and could be effectively activated by its ligand GAS6. Ligand-dependent Axl activation obviously rescued crizotinib-mediated suppression of cell proliferation in ALK-mutated NB cells. Genetic inhibition of Axl with specific small interfering RNA markedly increased the sensitivity of cells to ALK-TKIs. Furthermore, a small-molecule inhibitor of Axl significantly enhanced ALK-targeted therapy, as an increased frequency of apoptosis was observed in NB cells co-expressing ALK and Axl. Taken together, our results demonstrated that activation of Axl could lead to insensitivity to ALK inhibitors, and dual inhibition of ALK and Axl might be a potential therapeutic strategy against ALK-mutated NB.

  2. Faults Diagnostics of Railway Axle Bearings Based on IMF’s Confidence Index Algorithm for Ensemble EMD

    Science.gov (United States)

    Yi, Cai; Lin, Jianhui; Zhang, Weihua; Ding, Jianming

    2015-01-01

    As train loads and travel speeds have increased over time, railway axle bearings have become critical elements which require more efficient non-destructive inspection and fault diagnostics methods. This paper presents a novel and adaptive procedure based on ensemble empirical mode decomposition (EEMD) and Hilbert marginal spectrum for multi-fault diagnostics of axle bearings. EEMD overcomes the limitations that often hypothesize about data and computational efforts that restrict the application of signal processing techniques. The outputs of this adaptive approach are the intrinsic mode functions that are treated with the Hilbert transform in order to obtain the Hilbert instantaneous frequency spectrum and marginal spectrum. Anyhow, not all the IMFs obtained by the decomposition should be considered into Hilbert marginal spectrum. The IMFs’ confidence index arithmetic proposed in this paper is fully autonomous, overcoming the major limit of selection by user with experience, and allows the development of on-line tools. The effectiveness of the improvement is proven by the successful diagnosis of an axle bearing with a single fault or multiple composite faults, e.g., outer ring fault, cage fault and pin roller fault. PMID:25970256

  3. Changes in muscle size and MHC composition in response to resistance exercise with heavy and light loading intensity

    DEFF Research Database (Denmark)

    Holm, Lars; Reitelseder, Søren; Pedersen, T.G.

    2008-01-01

    Muscle mass accretion is accomplished by heavy-load resistance training. The effect of light-load resistance exercise has been far more sparsely investigated with regard to potential effect on muscle size and contractile strength. We applied a resistance exercise protocol in which the same indivi...... in healthy young men. However, LL resistance training was inferior to HL training in evoking adaptive changes in muscle size and contractile strength and was insufficient to induce changes in MHC composition.......Muscle mass accretion is accomplished by heavy-load resistance training. The effect of light-load resistance exercise has been far more sparsely investigated with regard to potential effect on muscle size and contractile strength. We applied a resistance exercise protocol in which the same.......05) in HL but remained unchanged in LL (4 +/- 5%, not significant). Finally, MHC IIX protein expression was decreased with HL but not LL, despite identical total workload in HL and LL. Our main finding was that LL resistance training was sufficient to induce a small but significant muscle hypertrophy...

  4. Rapid switch-off of the human myosin heavy chain IIX gene after heavy load muscle contractions is sustained for at least four days.

    Science.gov (United States)

    Andersen, J L; Gruschy-Knudsen, T

    2018-02-01

    Long-term heavy load contractions decrease the relative amount of the myosin heavy chain (MHC) IIX isoform in human skeletal muscle, but the timing of the down-regulation in the short term is unknown. Untrained subjects performed two resistance bouts, in two consecutive days, with one leg, the other leg serving as a control (age 24±1, n=5). Muscle biopsies were obtained in both legs before, immediately after, and 24, 54, and 96 hours after exercise. Serial cryosection analysis combined immunohistochemistry and ATPase histochemistry with In Situ hybridization to identify the distribution of MHC isoforms and their corresponding transcripts, enabling identification of transitional fibers. Fibers positive solely for MHC IIX mRNA decreased in the exercised leg throughout the study period. At 96 hours post-exercise, no fibers solely expressed MHC IIX mRNA. In contrast, the number of fibers expressing MHC IIA mRNA increased throughout the study period. The percentage of fibers expressing mRNA for MHC I was unchanged in both legs at all time points. Pronounced depletion of glycogen in the MHC IIX fibers of the exercised leg verifies that the type IIX fibers were active during the heavy load contractions. Major mismatch between MHC at the mRNA and protein levels was only found in the fibers of the exercised leg. These data provide unequivocal in situ evidence of an immediate shutdown of the MHC IIX gene after resistance exercise. A further novel finding was that the silencing of the MHC IIX gene is sustained at least 4 days after removal of the stimulus. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  5. Heavy Vehicles on Minor Highway Bridges

    DEFF Research Database (Denmark)

    Kirkegaard, Poul Henning; Nielsen, Søren R. K.; Enevoldsen, I.

    of heavier trucks moving at larger speeds, and partly because the authorities want to permit transportation of special heavy goods at a larger part of the road net. These needs will in many cases cause the strengthening of the bridges becomes necessary. In order to keep the expenses of such strengthening...... the results obtained using the numerical models given in details in "Heavy Vehicles on Minor Highway Bridges : dynamic modelling of vehicles and bridges". The models are established using a ordinary vehicle which consists of a 48 t Scania with a 3 axle tractor and a 3 axle trailer, joined in a flexible hinge...

  6. Field Measurement of Dynamic Compressive Stress Response of Pavement-Subgrade Induced by Moving Heavy-Duty Trucks

    Directory of Open Access Journals (Sweden)

    Lingshi An

    2018-01-01

    Full Text Available This paper presents the dynamic compressive stress response of pavement-subgrade induced by moving heavy-duty trucks. In order to study the distribution characteristic of dynamic pressure of pavement-subgrade in more detail, truck loadings, truck speeds, and dynamic pressure distributions at different depths were monitored under twenty-five working conditions on the section of Qiqihar-Nenjiang Highway in Heilongjiang Province, China. The effects of truck loading, truck speed, and depth on dynamic compressive stress response can be concluded as follows: (1 increasing truck loading will increase the dynamic pressure amplitude of subgrade-pavement and dominant frequencies are close to the characteristic frequencies caused by heavy-duty trucks at the speed of 70 km/h; (2 as truck speed increases, the dynamic pressure amplitudes of measuring points have an increasing tendency; the dynamic pressure spectrums are also significantly influenced by truck speed: the higher the truck speed, the wider the spectrum and the higher the dominant frequencies; (3 as depth increases, the dynamic pressure amplitudes of measuring points decrease rapidly. The influence of the front axle decreases gradually until disappearing and the compressive stress superposition phenomenon caused by rear double axles can be found with increasing depth.

  7. Constraints to obtaining consistent annual yields in perennial tree crops. I: Heavy fruit load dominates over vegetative growth.

    Science.gov (United States)

    Smith, Harley M; Samach, Alon

    2013-06-01

    Farmers lack effective methods to achieve and maintain stable production from year to year in many commercial fruit crops. Annual fruit yield within a region often alternates between high and low fruit load and is termed alternate bearing. The underlying cause of alternate bearing is the negative impact of high fruit load on vegetative growth and next year's flowering. In this review, we emphasize common responses of diverse perennials to heavy crop load. We present botanical, ecological and horticultural perspectives on irregular bearing. The later part of this review focuses on understanding how high fruit load dominates over vegetative growth. We discuss sink strengths and putative mobile signals (hormones), perhaps seed-derived. We highlight gaps in current understanding of alternate bearing, and discuss new approaches to better understand fruit load dominance. Assuming the effect of high fruit load may be related to other mechanisms of sink partitioning, other forms of dominance are presented such as apical, first fruit and king fruit dominance. Dominance seems to be enforced, in independent cases through the establishment of a polar auxin transport system from the stronger sink. Once established this somehow perturbs the transport of auxin out of weaker sinks. Possibly, fruit derived auxin may alter the polar auxin transport system of the shoot to inhibit shoot growth. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  8. Expression of Axl in Lung Adenocarcinoma and Correlation with Tumor Progression

    Directory of Open Access Journals (Sweden)

    Yi-Shing Shinh

    2005-12-01

    Full Text Available We used the Transwell system to select highly invasive cell lines from minimally invasive parent cells, and we compared gene expression in paired cell lines with high and low invasive potentials. Axl was relatively overexpressed in the highly invasive cell lines when compared with their minimally invasive counterparts. However, there is only limited information about the role of Axl in cancer invasion. The biologic function of Axl in tumor invasion was investigated by overexpression of full-length Axl in minimally invasive cells and by siRNA knockdown of Axl expression in highly invasive cells. Overexpression of Axl in minimally invasive cells increased their invasiveness. siRNA reduced cell invasiveness as Axl was downregulated in highly invasive cells. We further investigated the protein expression of Axl by immunohistochemistry and its correlation with clinicopathologic features. Data from a study of 58 patient specimens showed that Axl immunoreactivity was statistically significant with respect to lymph node status (P < .0001 and the patient's clinical stage (P < .0001. Our results demonstrate that Axl protein kinase seems to play an important role in the invasion and progression of lung cancer.

  9. The influence of axle position and the use of accessories on the activity of upper limb muscles during manual wheelchair propulsion.

    Science.gov (United States)

    Bertolaccini, Guilherme da Silva; Carvalho Filho, Idinei Francisco Pires de; Christofoletti, Gustavo; Paschoarelli, Luis Carlos; Medola, Fausto Orsi

    2018-06-01

    Wheelchair configuration is an important factor influencing the ergonomics of the user-device interface and, from a biomechanical point of view, small changes in chair setup may have a positive influence on the demand on the upper limbs during manual propulsion. This study aimed to investigate the influence of the position of the rear wheels' axle and the use of accessories on the activity of upper limb muscles during manual wheelchair propulsion. Electromyography signals of the biceps, triceps, anterior deltoids and pectoralis major were collected for 11 able-bodied subjects in a wheelchair propulsion protocol with four different wheelchair configurations (differing in axle position and the use of accessories) on a straightforward sprint and a slalom course. With accessories, moving the axle forward led to a decrease in the activity of all muscles in both the straightforward sprint (significant differences in triceps, anterior deltoids and biceps) and the slalom course (significant difference in anterior deltoids and biceps). However, when propelling the chair without accessories, no difference was found related to axle position. Changes in wheelchair configuration can influence the ergonomics of manual wheelchair propulsion. Reducing the biomechanical loads may benefit users' mobility, independence and social participation.

  10. Pollution load index for heavy metals in Mian-Ab plain soil, Khuzestan, Iran

    OpenAIRE

    Jorfi, Sahand; Maleki, Rohangiz; Jaafarzadeh, Neemat; Ahmadi, Mehdi

    2017-01-01

    Soil pollution by heavy metals is a major concern in agricultural area. Potential impact of heavy metals in agricultural soil on human health by accumulating in food chain demonstrated elsewhere.In this regard Mian-Ab plain as a major agricultural site of Khuzestan province considered for Arsenic, cadmium and lead concentration as the main potential toxic pollutants in soil. 50 topsoil samples were collected and analyzed by inductively coupled plasma mass spectrometry (ICP-MS). Also Contamina...

  11. Detection of early squats by axle box acceleration

    OpenAIRE

    Molodova, M.

    2013-01-01

    This thesis discusses a new method for detection of short track irregularities, particularly squats, with axle box acceleration (ABA) measurements. A squat is a surface initiated short track defect, associated with high frequency vibrations of the wheel-rail system. High stresses in the contact patch at squats cause accumulation of plastic deformation of the rail and growth of cracks. Cracks growing in the subsurface can cause a rail fracture. Light squats can be treated by grinding of the ra...

  12. The process of biosorption of heavy metals in bioreactors loaded with sanitary sewage sludge

    Directory of Open Access Journals (Sweden)

    A. J. Morais Barros

    2006-06-01

    Full Text Available This work on the process of biosorption of nickel and chromium in an ascendant continuous-flow, fixed packed-bed bioreactor of sanitary sewage sludge was conducted in a search for solutions to the environmental problem caused by heavy metals. Analysis of the results demonstrated that the absorbent had an extraordinary capacity for biosorption of the heavy metals studied at about 9.0 pH of the effluent, with a removal percentage of over 90.0% for the two metals. Chemometric study results demonstrated that 20 days of the experimental system function were sufficient for achieving the maximum efficiency of sorption of the heavy metals studied by the sanitary sewage sludge employed.

  13. Inhibition of the Receptor Tyrosine Kinase AXL Restores Paclitaxel Chemosensitivity in Uterine Serous Cancer.

    Science.gov (United States)

    Palisoul, Marguerite L; Quinn, Jeanne M; Schepers, Emily; Hagemann, Ian S; Guo, Lei; Reger, Kelsey; Hagemann, Andrea R; McCourt, Carolyn K; Thaker, Premal H; Powell, Matthew A; Mutch, David G; Fuh, Katherine C

    2017-12-01

    Uterine serous cancer (USC) is aggressive, and the majority of recurrent cases are chemoresistant. Because the receptor tyrosine kinase AXL promotes invasion and metastasis of USC and is implicated in chemoresistance in other cancers, we assessed the role of AXL in paclitaxel resistance in USC, determined the mechanism of action, and sought to restore chemosensitivity by inhibiting AXL in vitro and in vivo We used short hairpin RNAs and BGB324 to knock down and inhibit AXL. We assessed sensitivity of USC cell lines to paclitaxel and measured paclitaxel intracellular accumulation in vitro in the presence or absence of AXL. We also examined the role of the epithelial-mesenchymal transition (EMT) in AXL-mediated paclitaxel resistance. Finally, we treated USC xenografts with paclitaxel, BGB324, or paclitaxel plus BGB324 and monitored tumor burden. AXL expression was higher in chemoresistant USC patient tumors and cell lines than in chemosensitive tumors and cell lines. Knockdown or inhibition of AXL increased sensitivity of USC cell lines to paclitaxel in vitro and increased cellular accumulation of paclitaxel. AXL promoted chemoresistance even in cells that underwent the EMT in vitro Finally, in vivo studies of combination treatment with BGB324 and paclitaxel showed a greater than 51% decrease in tumor volume after 2 weeks of treatment when compared with no treatment or single-agent treatments ( P USC. Mol Cancer Ther; 16(12); 2881-91. ©2017 AACR . ©2017 American Association for Cancer Research.

  14. Electric axle. HV components and system; Elektrische Achse. HV-Komponenten und System

    Energy Technology Data Exchange (ETDEWEB)

    Schermann, Markus [Magna Powertrain, Oberwaltersdorf (Austria). Elektrische Antriebssysteme

    2013-03-15

    Magna Powertrain introduces the system of an electric rear axle drive. The system consists of an electric machine integrated into the gearbox and an appropriate inverter. The system is used to apply power to the rear axle while a conventional combustion engine drives the front axle. This kind of parallel hybrid approach is called ''through-the-road-hybrid'' because the total power of both combustion engine and electric motor is applied through the road at different axles. With this approach, the all-wheel drive functionality is covered as well.

  15. Assessment of Surficial Loads of Heavy Metals in sediment of Ipo ...

    African Journals Online (AJOL)

    PROF HORSFALL

    Commons Attribution License (CCL), which permits unrestricted use, ... medium, provided the original work is properly cited. ... toxicants terminates in the aquatic system as a result ... Statistical analysis: One way analysis of variance. (ANOVA) .... Table 4: Ecological risk factors for heavy metals in Ipo and Sombriero sediment.

  16. Heavy metals load in tilapia species: a case study of Jakara river ...

    African Journals Online (AJOL)

    12) from each site were sampled from Jakara River and Kusalla dam in Kano, Nigeria with the view to determine the level of some heavy metals in the muscles of the fishes so as to assess their safety or otherwise for human consumption.

  17. Carbonaceous composition changes of heavy-duty diesel engine particles in relation to biodiesels, aftertreatments and engine loads.

    Science.gov (United States)

    Cheng, Man-Ting; Chen, Hsun-Jung; Young, Li-Hao; Yang, Hsi-Hsien; Tsai, Ying I; Wang, Lin-Chi; Lu, Jau-Huai; Chen, Chung-Bang

    2015-10-30

    Three biodiesels and two aftertreatments were tested on a heavy-duty diesel engine under the US FTP transient cycle and additional four steady engine loads. The objective was to examine their effects on the gaseous and particulate emissions, with emphasis given to the organic and elemental carbon (OC and EC) in the total particulate matter. Negligible differences were observed between the low-sulfur (B1S50) and ultralow-sulfur (B1S10) biodiesels, whereas small reductions of OC were identified with the 10% biodiesel blend (B10). The use of diesel oxidation catalyst (DOC1) showed moderate reductions of EC and particularly OC, resulting in the OC/EC ratio well below unity. The use of DOC plus diesel particulate filter (DOC2+DPF) yielded substantial reductions of OC and particularly EC, resulting in the OC/EC ratio well above unity. The OC/EC ratios were substantially above unity at idle and low load, whereas below unity at medium and high load. The above changes in particulate OC and EC are discussed with respect to the fuel content, pollutant removal mechanisms and engine combustion conditions. Overall, the present study shows that the carbonaceous composition of PM could change drastically with engine load and aftertreatments, and to a lesser extent with the biodiesels under study. Copyright © 2015 Elsevier B.V. All rights reserved.

  18. Carbonaceous composition changes of heavy-duty diesel engine particles in relation to biodiesels, aftertreatments and engine loads

    Energy Technology Data Exchange (ETDEWEB)

    Cheng, Man-Ting; Chen, Hsun-Jung [Department of Environmental Engineering, National Chung Hsing University, 250 Kuo-Kuang Road, Taichung 40254, Taiwan (China); Young, Li-Hao, E-mail: lhy@mail.cmu.edu.tw [Department of Occupational Safety and Health, China Medical University, 91 Hsueh-Shih Road, Taichung 40402, Taiwan (China); Yang, Hsi-Hsien [Department of Environmental Engineering and Management, Chaoyang University of Technology, 168, Jifeng E. Road, Wufeng District, Taichung 41349, Taiwan (China); Tsai, Ying I. [Department of Environmental Engineering and Science, Chia Nan University of Pharmacy and Science, 60, Sec. 1, Erren Rd., Rende District, Tainan 71710, Taiwan (China); Wang, Lin-Chi [Department of Civil Engineering and Geomatics, Cheng Shiu University, 840, Chengcing Road, Niaosong District, Kaohsiung 83347, Taiwan (China); Lu, Jau-Huai [Department of Mechanical Engineering, National Chung Hsing University, 250 Kuo-Kuang Road, Taichung 40254, Taiwan (China); Chen, Chung-Bang [Fuel Quality and Engine Performance Research, Refining and Manufacturing Research Institute, Chinese Petroleum Corporation, 217, Minsheng S. Road, West District, Chiayi 60051, Taiwan (China)

    2015-10-30

    Highlights: • We study particulate OC and EC under 3 fuels, 2 aftertreatments and 4 engine loads. • Negligible to minor OC and EC changes with low, ultralow sulfur and 10% biodiesels. • Moderate reductions of EC and particularly OC from diesel oxidation catalyst (DOC). • Large reductions of OC and particularly EC from DOC plus diesel particulate filter. • Highest at idle, whereas OC decreases but EC increases from low to high load. - Abstract: Three biodiesels and two aftertreatments were tested on a heavy-duty diesel engine under the US FTP transient cycle and additional four steady engine loads. The objective was to examine their effects on the gaseous and particulate emissions, with emphasis given to the organic and elemental carbon (OC and EC) in the total particulate matter. Negligible differences were observed between the low-sulfur (B1S50) and ultralow-sulfur (B1S10) biodiesels, whereas small reductions of OC were identified with the 10% biodiesel blend (B10). The use of diesel oxidation catalyst (DOC1) showed moderate reductions of EC and particularly OC, resulting in the OC/EC ratio well below unity. The use of DOC plus diesel particulate filter (DOC2+DPF) yielded substantial reductions of OC and particularly EC, resulting in the OC/EC ratio well above unity. The OC/EC ratios were substantially above unity at idle and low load, whereas below unity at medium and high load. The above changes in particulate OC and EC are discussed with respect to the fuel content, pollutant removal mechanisms and engine combustion conditions. Overall, the present study shows that the carbonaceous composition of PM could change drastically with engine load and aftertreatments, and to a lesser extent with the biodiesels under study.

  19. Carbonaceous composition changes of heavy-duty diesel engine particles in relation to biodiesels, aftertreatments and engine loads

    International Nuclear Information System (INIS)

    Cheng, Man-Ting; Chen, Hsun-Jung; Young, Li-Hao; Yang, Hsi-Hsien; Tsai, Ying I.; Wang, Lin-Chi; Lu, Jau-Huai; Chen, Chung-Bang

    2015-01-01

    Highlights: • We study particulate OC and EC under 3 fuels, 2 aftertreatments and 4 engine loads. • Negligible to minor OC and EC changes with low, ultralow sulfur and 10% biodiesels. • Moderate reductions of EC and particularly OC from diesel oxidation catalyst (DOC). • Large reductions of OC and particularly EC from DOC plus diesel particulate filter. • Highest at idle, whereas OC decreases but EC increases from low to high load. - Abstract: Three biodiesels and two aftertreatments were tested on a heavy-duty diesel engine under the US FTP transient cycle and additional four steady engine loads. The objective was to examine their effects on the gaseous and particulate emissions, with emphasis given to the organic and elemental carbon (OC and EC) in the total particulate matter. Negligible differences were observed between the low-sulfur (B1S50) and ultralow-sulfur (B1S10) biodiesels, whereas small reductions of OC were identified with the 10% biodiesel blend (B10). The use of diesel oxidation catalyst (DOC1) showed moderate reductions of EC and particularly OC, resulting in the OC/EC ratio well below unity. The use of DOC plus diesel particulate filter (DOC2+DPF) yielded substantial reductions of OC and particularly EC, resulting in the OC/EC ratio well above unity. The OC/EC ratios were substantially above unity at idle and low load, whereas below unity at medium and high load. The above changes in particulate OC and EC are discussed with respect to the fuel content, pollutant removal mechanisms and engine combustion conditions. Overall, the present study shows that the carbonaceous composition of PM could change drastically with engine load and aftertreatments, and to a lesser extent with the biodiesels under study

  20. Determination of Actual Friction Factors in Metal Forming under Heavy Loaded Regimes Combining Experimental and Numerical Analysis

    Science.gov (United States)

    Camacho, Ana María; Veganzones, Mariano; Claver, Juan; Martín, Francisco; Sevilla, Lorenzo; Sebastián, Miguel Ángel

    2016-01-01

    Tribological conditions can change drastically during heavy loaded regimes as experienced in metal forming; this is especially critical when lubrication can only be applied at the early stage of the process because the homogeneous lubricant layer can break along the die-workpiece interface. In these cases, adopting a constant friction factor for the lubricant-surface pair may not be a valid assumption. This paper presents a procedure based on the use of dual friction factor maps to determine friction factors employed in heavy loaded regimes. A finite element (FE) simulation is used to obtain the friction factor map for the alloy UNS A96082. Experiments were conducted using four lubricants (aluminum anti-size, MoS2 grease, silicone oil, and copper paste) to determine the actual friction curves. The experimental procedure is based on the application of lubricant only at the beginning of the first stage of ring compression, and not at intermediate stages as is usual in typical ring compression tests (RCTs). The results show that for small reductions (rh 20%), it is recommended to obtain an average value of the friction factor for every lubricant-surface pair in the range of deformation considered. PMID:28773868

  1. Determination of Actual Friction Factors in Metal Forming under Heavy Loaded Regimes Combining Experimental and Numerical Analysis

    Directory of Open Access Journals (Sweden)

    Ana María Camacho

    2016-09-01

    Full Text Available Tribological conditions can change drastically during heavy loaded regimes as experienced in metal forming; this is especially critical when lubrication can only be applied at the early stage of the process because the homogeneous lubricant layer can break along the die-workpiece interface. In these cases, adopting a constant friction factor for the lubricant-surface pair may not be a valid assumption. This paper presents a procedure based on the use of dual friction factor maps to determine friction factors employed in heavy loaded regimes. A finite element (FE simulation is used to obtain the friction factor map for the alloy UNS A96082. Experiments were conducted using four lubricants (aluminum anti-size, MoS2 grease, silicone oil, and copper paste to determine the actual friction curves. The experimental procedure is based on the application of lubricant only at the beginning of the first stage of ring compression, and not at intermediate stages as is usual in typical ring compression tests (RCTs. The results show that for small reductions (rh < 20%, the conventional RCT can be applied because the tribological conditions remain similar. For large reductions (rh > 20%, it is recommended to obtain an average value of the friction factor for every lubricant-surface pair in the range of deformation considered.

  2. PREFIT project: Integration of man-in-the-loop and automation for manipulation of heavy loads and forces in ITER

    Energy Technology Data Exchange (ETDEWEB)

    Dubus, G. [CEA, LIST, Interactive Robotics Unit, 18 route du Panorama, BP6, Fontenay-aux-Roses F-92265 (France)], E-mail: gregory.dubus@cea.fr; David, O.; Measson, Y.; Friconneau, J.-P. [CEA, LIST, Interactive Robotics Unit, 18 route du Panorama, BP6, Fontenay-aux-Roses F-92265 (France)

    2009-06-15

    Operating within the framework of the Euratom Fusion Training Scheme (EFTS), the PREFIT partnership prepares remote handling (RH) engineers for ITER with an integrated programme of training and research over 3 years. One of the research topics aims at improving effectiveness and safety of remote handling manipulation of heavy loads, a significant challenge associated with ITER's maintenance scheme. In all areas needing scheduled maintenance work - in-vessel components, neutral beam injector, hot cells - introduction of man-in-the-loop technologies would provide very useful help in case of unexpected events. The focus of this work is the problem of vibrations experienced when handling heavy loads using flexible robotic structures. Vibrations are induced during start and stop movements, high accelerations or in the case of collision. It is therefore necessary to develop strategies to remove undesired effects of stimulating dynamics or critical trajectories. Analysis of previous works on flexible arms proves that model-based control of light structures gives good performance providing that dynamic terms take into account the compliance of the joints and the structural deformation.

  3. Effects of extreme-duration heavy load carriage on neuromuscular function and locomotion: a military-based study.

    Directory of Open Access Journals (Sweden)

    Jordane G Grenier

    Full Text Available Trekking and military missions generally consist of carrying heavy loads for extreme durations. These factors have been separately shown to be sources of neuromuscular (NM fatigue and locomotor alterations. However, the question of their combined effects remains unresolved, and addressing this issue required a representative context.The aim was to investigate the effects of extreme-duration heavy load carriage on NM function and walking characteristics.Ten experienced infantrymen performed a 21-h simulated military mission (SMM in a middle-mountain environment with equipment weighing ∼27 kg during battles and ∼43 kg during marches. NM function was evaluated for knee extensors (KE and plantar flexors (PF pre- and immediately post-SMM using isometric maximal voluntary contraction (MVC measurement, neural electrical stimulation and surface EMG. The twitch-interpolation method was used to assess central fatigue. Peripheral changes were examined by stimulating the muscle in the relaxed state. The energy cost, mechanical work and spatio-temporal pattern of walking were also evaluated pre-/post-SMM on an instrumented treadmill in three equipment conditions: Sportswear, Battle and March.After the SMM, MVC declined by -10.2±3.6% for KE (P<0.01 and -10.7±16.1% for PF (P = 0.06. The origin of fatigue was essentially peripheral for both muscle groups. A trend toward low-frequency fatigue was detected for KE (5.5%, P = 0.08. These moderate NM alterations were concomitant with a large increase in perceived fatigue from pre- (rating of 8.3±2.2 to post-SMM (15.9±2.1, P<0.01. The SMM-related fatigue did not alter walking energetics or mechanics, and the different equipment carried on the treadmill did not interact with this fatigue either.this study reports the first data on physiological and biomechanical consequences of extreme-duration heavy load carriage. Unexpectedly, NM function alterations due to the 21-h SMM were moderate and did not

  4. Effects of extreme-duration heavy load carriage on neuromuscular function and locomotion: a military-based study.

    Science.gov (United States)

    Grenier, Jordane G; Millet, Guillaume Y; Peyrot, Nicolas; Samozino, Pierre; Oullion, Roger; Messonnier, Laurent; Morin, Jean-Benoît

    2012-01-01

    Trekking and military missions generally consist of carrying heavy loads for extreme durations. These factors have been separately shown to be sources of neuromuscular (NM) fatigue and locomotor alterations. However, the question of their combined effects remains unresolved, and addressing this issue required a representative context. The aim was to investigate the effects of extreme-duration heavy load carriage on NM function and walking characteristics. Ten experienced infantrymen performed a 21-h simulated military mission (SMM) in a middle-mountain environment with equipment weighing ∼27 kg during battles and ∼43 kg during marches. NM function was evaluated for knee extensors (KE) and plantar flexors (PF) pre- and immediately post-SMM using isometric maximal voluntary contraction (MVC) measurement, neural electrical stimulation and surface EMG. The twitch-interpolation method was used to assess central fatigue. Peripheral changes were examined by stimulating the muscle in the relaxed state. The energy cost, mechanical work and spatio-temporal pattern of walking were also evaluated pre-/post-SMM on an instrumented treadmill in three equipment conditions: Sportswear, Battle and March. After the SMM, MVC declined by -10.2±3.6% for KE (P<0.01) and -10.7±16.1% for PF (P = 0.06). The origin of fatigue was essentially peripheral for both muscle groups. A trend toward low-frequency fatigue was detected for KE (5.5%, P = 0.08). These moderate NM alterations were concomitant with a large increase in perceived fatigue from pre- (rating of 8.3±2.2) to post-SMM (15.9±2.1, P<0.01). The SMM-related fatigue did not alter walking energetics or mechanics, and the different equipment carried on the treadmill did not interact with this fatigue either. this study reports the first data on physiological and biomechanical consequences of extreme-duration heavy load carriage. Unexpectedly, NM function alterations due to the 21-h SMM were moderate and did not alter

  5. Impact of Surface Type, Wheelchair Weight, and Axle Position on Wheelchair Propulsion by Novice Older Adults

    Science.gov (United States)

    Cowan, Rachel E.; Nash, Mark S.; Collinger, Jennifer L.; Koontz, Alicia M.; Boninger, Michael L.

    2009-01-01

    Objective To examine the impact of surface type, wheelchair weight, and rear axle position on older adult propulsion biomechanics. Design Crossover trial. Setting Biomechanics laboratory. Participants Convenience sample of 53 ambulatory older adults with minimal wheelchair experience (65−87y); men = 20, women = 33. Intervention Participants propelled 4 different wheelchair configurations over 4 surfaces; tile, low carpet, high carpet, and an 8% grade ramp (surface, chair order randomized). Chair configurations included: (1) unweighted chair with an anterior axle position, (2) 9.05kg weighted chair with an anterior axle position, (3) unweighted chair with a posterior axle position (Δ0.08m), and (4) 9.05kg weighted chair with a posterior axle position (Δ0.08m). Weight was added to a titanium folding chair, simulating the weight difference between very light and depot wheelchairs. Instrumented wheels measured propulsion kinetics. Main Outcome Measures Average self-selected velocity, push-frequency, stroke length, peak resultant and tangential force. Results Velocity decreased as surface rolling resistance or chair weight increased. Peak resultant and tangential forces increased as chair weight increased, surface resistance increased, and with a posterior axle position. The effect of a posterior axle position was greater on high carpet and the ramp. The effect of weight was constant, but more easily observed on high carpet and ramp. The effects of axle position and weight were independent of one another. Conclusion Increased surface resistance decreases self-selected velocity and increases peak forces. Increased weight decreases self-selected velocity and increases forces. Anterior axle positions decrease forces, more so on high carpet. Effects of weight and axle position are independent. Greatest reductions in peak forces occur in lighter chairs with anterior axle positions. PMID:19577019

  6. Axl receptor tyrosine kinase is up-regulated in metformin resistant prostate cancer cells

    Science.gov (United States)

    Bansal, Nitu; Mishra, Prasun J.; Stein, Mark; DiPaola, Robert S.; Bertino, Joseph R.

    2015-01-01

    Recent epidemiological studies showed that metformin, a widely used anti-diabetic drug might prevent certain cancers. Metformin also has an anti-proliferative effect in preclinical studies of both hematologic malignancies as well as solid cancers and clinical studies testing metformin as an anti-cancer drug are in progress. However, all cancer types do not respond to metformin with the same effectiveness or acquire resistance. To understand the mechanism of acquired resistance and possibly its mechanism of action as an anti-proliferative agent, we developed metformin resistant LNCaP prostate cancer cells. Metformin resistant LNCaP cells had an increased proliferation rate, increased migration and invasion ability as compared to the parental cells, and expressed markers of epithelial-mesenchymal transition (EMT). A detailed gene expression microarray comparing the resistant cells to the wild type cells revealed that Edil2, Ereg, Axl, Anax2, CD44 and Anax3 were the top up-regulated genes and calbindin 2 and TPTE (transmembrane phosphatase with tensin homology) and IGF1R were down regulated. We focused on Axl, a receptor tyrosine kinase that has been shown to be up regulated in several drug resistance cancers. Here, we show that the metformin resistant cell line as well as castrate resistant cell lines that over express Axl were more resistant to metformin, as well as to taxotere compared to androgen sensitive LNCaP and CWR22 cells that do not overexpress Axl. Forced overexpression of Axl in LNCaP cells decreased metformin and taxotere sensitivity and knockdown of Axl in resistant cells increased sensitivity to these drugs. Inhibition of Axl activity by R428, a small molecule Axl kinase inhibitor, sensitized metformin resistant cells that overexpressed Axl to metformin. Inhibitors of Axl may enhance tumor responses to metformin and other chemotherapy in cancers that over express Axl. PMID:26036314

  7. Monitoring of Heavy Metal Loading into the Wetlands South of Lake ...

    African Journals Online (AJOL)

    Wetlands impacted by gold mining activities in the South Lake Victoria basin show elevated heavy metal contents in soil and sediment, particularly Cu (13-415 mg/kg), Pb (24-94 mg/kg), Zn (9-80 mg/kg), Cr (19-77 mg/kg), Ni (12-37 mg/kg) and Hg (0.19-1.76 mg/kg), contrary to non-impacted wetlands, which contain ...

  8. Monitoring of heavy metal load - by mosses or rain water chemistry

    Energy Technology Data Exchange (ETDEWEB)

    Ruoho-Airola, T. [Finnish Meteorological Inst., Helsinki (Finland); Maekelae, K. [National Board of Waters and the Environment, Helsinki (Finland)

    1995-12-31

    The deposition of heavy metals is usually determined from precipitation chemistry but the moss technique has been increasingly used, particularly in the Nordic countries. Some international monitoring programmes, e.g. UN/ECE Integrated Monitoring, give them as alternative methods. However, their comparability has not been sufficiently determined. This study compares the two monitoring methods for Pb, Cd, Cu and Zn, which have different sources. The metal industry is an important source of Pb and Cd emissions. Long- range transport as well as traffic and local emissions are also important sources for Pb. The use of fertilizers and fossil fuels also result in Cd emissions. Cu and Zn are emitted from metal industries and local sources. Unlike Pb and Cd, Cu and Zn are essential elements for living organisms. Cu and Zn are needed in many enzymes and Zn in proteins. Mosses are thought to take all their nutrients from the air. The deposition of heavy metals is also effectively retained by mosses and may be used to indicate levels of heavy metal deposition. In northern countries the mosses are isolated from air (and therefore also from deposition) by snow in winter. In this study both the bulk deposition of the whole year (later `total deposition`) and the bulk deposition of the snow-free period (later `bare ground deposition`) are compared to the metal concentrations in mosses. (author)

  9. Monitoring of heavy metal load - by mosses or rain water chemistry

    Energy Technology Data Exchange (ETDEWEB)

    Ruoho-Airola, T [Finnish Meteorological Inst., Helsinki (Finland); Maekelae, K [National Board of Waters and the Environment, Helsinki (Finland)

    1996-12-31

    The deposition of heavy metals is usually determined from precipitation chemistry but the moss technique has been increasingly used, particularly in the Nordic countries. Some international monitoring programmes, e.g. UN/ECE Integrated Monitoring, give them as alternative methods. However, their comparability has not been sufficiently determined. This study compares the two monitoring methods for Pb, Cd, Cu and Zn, which have different sources. The metal industry is an important source of Pb and Cd emissions. Long- range transport as well as traffic and local emissions are also important sources for Pb. The use of fertilizers and fossil fuels also result in Cd emissions. Cu and Zn are emitted from metal industries and local sources. Unlike Pb and Cd, Cu and Zn are essential elements for living organisms. Cu and Zn are needed in many enzymes and Zn in proteins. Mosses are thought to take all their nutrients from the air. The deposition of heavy metals is also effectively retained by mosses and may be used to indicate levels of heavy metal deposition. In northern countries the mosses are isolated from air (and therefore also from deposition) by snow in winter. In this study both the bulk deposition of the whole year (later `total deposition`) and the bulk deposition of the snow-free period (later `bare ground deposition`) are compared to the metal concentrations in mosses. (author)

  10. 49 CFR 230.100 - Defects in tender truck axles and journals.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Defects in tender truck axles and journals. 230... Steam Locomotives and Tenders Running Gear § 230.100 Defects in tender truck axles and journals. (a... wheel seats that is more than 1/8 of an inch in depth. (b) Tender truck journal condemning defects...

  11. Axl acts as a tumor suppressor by regulating LIGHT expression in T lymphoma

    Science.gov (United States)

    Young, Kon-Ji; Park, A-Reum; Choi, Ha-Rim; Lee, Hwa-Youn; Kim, Su-Man; Chung, Byung Yeoup; Park, Chul-Hong; Choi, Hyo Jin; Ko, Young-Hyeh; Bai, Hyoung-Woo; Kang, Hyung-Sik

    2017-01-01

    Axl is an oncogenic receptor tyrosine kinase that plays a role in many cancers. LIGHT (Lymphotoxin-related inducible ligand that competes for glycoprotein D binding to herpesvirus entry mediator on T cells) is a ligand that induces robust anti-tumor immunity by enhancing the recruitment and activation of effector immune cells at tumor sites. We observed that mouse EL4 and human Jurkat T lymphoma cells that stably overexpressed Axl also showed high expression of LIGHT. When Jurkat-Axl cells were treated with Gas6, a ligand for Axl, LIGHT expression was upregulated through activation of the PI3K/AKT signaling pathway and transcriptional induction by Sp1. The lytic activity of cytotoxic T lymphocytes and natural killer cells was enhanced by EL4-Axl cells. In addition, tumor volume and growth were markedly reduced due to enhanced apoptotic cell death in EL4-Axl tumor-bearing mice as compared to control mice. We also observed upregulated expression of CCL5 and its receptor, CCR5, and enhanced intratumoral infiltration of cytotoxic T lymphocytes and natural killer cells in EL4-Axl-bearing mice as compared to mock controls. These data strongly suggested that Axl exerts novel tumor suppressor effects by inducing upregulation of LIGHT in the tumor microenvironment of T lymphoma. PMID:28423548

  12. On the Transverse motions under heavy loads of thin beams with ...

    African Journals Online (AJOL)

    In this paper, the effect of variable axial force on the dynamic response of elastic beam resting on elastic foundation and subjected to concentrated moving loads is investigated. The fourth order partial differential equation with variable and singular coefficients governing the motion of the elastic thin beam is solved using the ...

  13. Muscle activation strategies during strength training with heavy loading versus repetitions to failure

    DEFF Research Database (Denmark)

    Sundstrup, Emil; Jakobsen, Markus D; Andersen, Christoffer H

    2012-01-01

    . Electromyographic (EMG) amplitude and median power frequency (MPF) of specific shoulder and neck muscles was analysed and the Borg CR10 scale was used to rate perceived loading immediately after each set of exercise. During the failure set normalized EMG was significantly lower during the first repetition...

  14. Heating Processes Of The Axle-Boxes Of Rolling-Stock On Railway Track Curves

    Directory of Open Access Journals (Sweden)

    Olegas Lunys

    2013-12-01

    Full Text Available The article deals with the heating process of the axle-boxes ofrolling stock when the train is in motion and discusses the forcesacting on the wheel-set when rolling stock moves along the trackcurves. The paper analyses scientific publications relevant tothe forces acting on the wheel-set of rolling stock and focuseson the axle-box heating process. The article also discusses theresults of theoretical studies on wheel-set forces that affect theheat exchange process of axle-boxes for a railway vehicle. Theresearch has determined a change in heating temperatures ofdifferent axle-boxes of rolling stock and reasons for their variationsand tendencies. The paper has estimated an effect of thetrain running along the track curves on the heating intensity ofthe axle-box. Finally, valid conclusions and recommendationshave been provided.

  15. Therapeutic Targeting of AXL Receptor Tyrosine Kinase Inhibits Tumor Growth and Intraperitoneal Metastasis in Ovarian Cancer Models

    Directory of Open Access Journals (Sweden)

    Pinar Kanlikilicer

    2017-12-01

    Full Text Available Despite substantial improvements in the treatment strategies, ovarian cancer is still the most lethal gynecological malignancy. Identification of drug treatable therapeutic targets and their safe and effective targeting is critical to improve patient survival in ovarian cancer. AXL receptor tyrosine kinase (RTK has been proposed to be an important therapeutic target for metastatic and advanced-stage human ovarian cancer. We found that AXL-RTK expression is associated with significantly shorter patient survival based on the The Cancer Genome Atlas patient database. To target AXL-RTK, we developed a chemically modified serum nuclease-stable AXL aptamer (AXL-APTAMER, and we evaluated its in vitro and in vivo antitumor activity using in vitro assays as well as two intraperitoneal animal models. AXL-aptamer treatment inhibited the phosphorylation and the activity of AXL, impaired the migration and invasion ability of ovarian cancer cells, and led to the inhibition of tumor growth and number of intraperitoneal metastatic nodules, which was associated with the inhibition of AXL activity and angiogenesis in tumors. When combined with paclitaxel, in vivo systemic (intravenous [i.v.] administration of AXL-aptamer treatment markedly enhanced the antitumor efficacy of paclitaxel in mice. Taken together, our data indicate that AXL-aptamers successfully target in vivo AXL-RTK and inhibit its AXL activity and tumor growth and progression, representing a promising strategy for the treatment of ovarian cancer.

  16. Failure analysis of axle shaft of a fork lift

    Directory of Open Access Journals (Sweden)

    Souvik Das

    2015-04-01

    Full Text Available An axle shaft of fork lift failed at operation within 296 h of service. The shaft transmits torque from discrepancy to wheel through planetary gear arrangement. A section of fractured axle shaft made of induction-hardened steel was analyzed to determine the root cause of the failure. Optical microscopies as well as field emission gun scanning electron microscopy (FEG-SEM along with energy dispersive spectroscopy (EDS were carried out to characterize the microstructure. Hardness profile throughout the cross-section was evaluated by micro-hardness measurements. Chemical analysis indicated that the shaft was made of 42CrMo4 steel grade as per specification. Microstructural analysis and micro-hardness profile revealed that the shaft was improperly heat treated resulting in a brittle case, where crack was found to initiate from the case in a brittle mode in contrast to ductile mode within the core. This behaviour was related to differences in microstructure, which was observed to be martensitic within the case with a micro-hardness equivalent to 735 HV, and a mixture of non-homogeneous structure of pearlite and ferrite within the core with a hardness of 210 HV. The analysis suggests that the fracture initiated from the martensitic case as brittle mode due to improper heat treatment process (high hardness. Moreover the inclusions along the hot working direction i.e. in the longitudinal axis made the component more susceptible to failure.

  17. Nutrients and heavy metals loads at the mouth of the river Adda in the lake of Como

    International Nuclear Information System (INIS)

    Ruggeri, R.; Mocellin, L.

    1996-01-01

    Among the regional instructions about the improvement of the quality of the superficial waters, the nutrients and the heavy metals conveyed by the Adda river in the lake of Como has been determined. Total phosphorous, total nitrogen TKN, cadmium, chromium, nickel, lead, copper and zinc concentrations has been carried out in 1994 among a programme of weekly sampling. Total phosphorous and nitrogen concentrations has been related with the compatible loads determined for the river Adda by the plan of the Lombardy Region of waters restoration to health. Metals concentrations has been evaluated both in comparison with data obtained for others rivers flows and with the results of previous studies on the waters sediments in the lake of Como

  18. Low-Speed Control of Heavy-Load Transfer Robot with Long Telescopic Boom Based on Stribeck Friction Model

    Directory of Open Access Journals (Sweden)

    Bo You

    2012-01-01

    Full Text Available The severe low-speed creep phenomenon occurs in the telescopic boom system of a heavy-load transfer robot with a long telescopic boom as a result of nonlinear friction. In order to improve control precision and operation performance at low speeds, we built a three-loop control nonlinear model of an AC servo motor with Stribeck friction disturbance. Traditional proportional-integral-derivative controller (PID and fuzzy PID controls were, respectively, adopted in the position loop, and the control performance was simulated. The results showed that a system with fuzzy PID control eliminates “flat top” position tracking and “dead zone” speed tracking, which are generated by traditional PID, and thereby decreases the effect of friction on the performance of the servo system. This elimination also improved the tracking accuracy and robustness of the system.

  19. Runoff and loads of nutrients and heavy metals from an urbanized area.

    Science.gov (United States)

    Shirasuna, H; Fukushima, T; Matsushige, K; Imai, A; Ozaki, N

    2006-01-01

    To investigate the run-off characteristics of dissolved and particulate substances from a heavily urbanized area (basin area: 95 ha, percentage of impervious surfaces: 60%), sensors for measuring water level, water temperature, DO, pH, electric conductivity (EC), turbidity and ammonium ion were placed in the channel connecting storm sewers and natural river, together with water sampling for analyzing SS, nutrients and metals. While both turbidity and EC showed apparent "first flush", the peaks of EC were always earlier than those of turbidity. In a similar manner, dissolved nutrients and metals exhibited earlier "first flush" compared with particulate nutrients and acid-extractable metals. Significantly positive correlations between EC and dissolved substances as well as those between turbidity and particulate (acid-extractable minus dissolved) substances were usually observed, and two distinct different regressions were found between the two datasets separated before and after the concentration peaks. Using these relationships, the total loads during the respective rainfall events were calculated on the basis of EC and turbidity changes. The total loads of nitrogen, zinc, etc. were nearly proportional to the lengths of non-rainfall periods before the events, indicating that these loads derived from the atmospheric deposition.

  20. Spatial and Seasonal Variations of Heavy Metal Loads in Uyo Urban Drainage Stream under PS and NPS Pollution

    Directory of Open Access Journals (Sweden)

    O. E. Essien

    2012-12-01

    Full Text Available The concentration of heavy metals (HM in the 4km urban drainage stream in Uyo was studied using grab and composite sampling of water from six stations on the stream, and analyzed by a multipurpose atomic absorption spectrophotometer. The data were statistically analyzed using SPSS version 17 software arid correlated between stations and among samples. HM contamination was evaluated with the coefficient and rate of dispersion between stations and the Normalized Scatter Coefficient (NSC. The seasonal distribution of metal pollution varied individually amongst metals at stations. The Fe and Pb concentrations exceeded the safe drinking water standard, rendering the water quality not acceptable for drinking; however, the quality was within the safe limit for crop production along the river bank. The relative.dominance of heavy metals followed a different sequence in upstream leachate effluent from all downstream stations. The NSC in dry-wet season was higher than in wet season, and was in the order: Fe>Cu>Zn>Pb, showing that large but variable concentration of Fe from PS and NPS contaminated the stream at faster rate in the wet season while Pb contaminated at nearly constant rate. However, in the dry season, Fe and Pb depleted at downstream at rates far higher than Zn as Cu was increasing. Fe and Pb could be good pollution monitor for total maximum daily load (TMDL pollution monitoring programme.

  1. Evaluation of some heavy metal loading in the Kpeshi lagoon, Ghana

    Science.gov (United States)

    Fianko, Joseph R.; Laar, Cynthia; Osei, Juilet; Anim, Alfred K.; Gibrilla, Abass; Adomako, Dickson

    2013-03-01

    A study was carried out on the Kpeshi lagoon to evaluate the relative contributions of some heavy metals (Na, k, Ca, K, Fe, Mn, Ni, Cr, Cd, Al, Pb) on the current state of the Kpeshi lagoon. The lagoon water was sampled along with some fish samples. Water pH, electrical conductivity and total dissolved salts were measured in situ whilst Na and K were measured using flame emission spectrometry. Heavy metals (iron, manganese, nickel, aluminium, chromium, lead and cadmium) in both water and fish samples were analyzed using atomic absorption spectrometry. Measured pH values ranged between 6.60 and 7.87, a mean conductivity and total dissolved salts of 87.31 ± 19.14 μS/cm and 38.4 ± 8.43 mg/L, respectively. Nutrient and organic matter were among the frequent source of pollution in the lagoon with mean sulphate, phosphate and nitrate concentrations of 190 ± 108.84, 1.62 ± 0.49 and 0.89 ± 0.26 mg/L, respectively. Iron and aluminium in the lagoon water measured the highest concentration of 13.2 ± 3.47 and 13.6 ± 4.29 mg/L, respectively. Fish samples however revealed very high concentrations of calcium and potassium measuring 15,709 ± 75.35 and 5,949.49 ± 87.30 mg/kg, respectively. Sodium and aluminium also revealed relatively high concentrations: 3,775.70 ± 24.80 and 708.47 ± 4.95 mg/kg, respectively. Notably, sites closer to settlement community (Teshie Township, e.g. S1, S2, S3 and S4) and the hospitality industries (i.e. dotted hotels, e.g. S7) appeared to be relatively more contaminated.

  2. Control instrumentation and data handling of heavy current inductive load interrupter

    International Nuclear Information System (INIS)

    Calpin, J.E.

    1983-01-01

    The heavy duty DC interrupter is a switching system with the ability to interrupt very high inductive currents with precise timing, work in concert with an additional number of similar systems, and withstand fast recovery voltages (30 kV) after interruption. Further, it is required to be self-protecting and the high current busses isolated to 50 kV DC and subjected to 95 kV BIL test voltages. Interruption is accomplished by the separation of vacuum interrupter contacts, which prior to counterpulse arc for milliseconds, generating horrendous noise signals of frequencies from DC to ultraviolet. Neutralization of such signals on the computer interface was effected by unique BALUN filters on 25 control and status lines. The noise abatement circuitry rationale will be discussed along with triple shielding, Hall effect current level sensing and light pipe communication between high level busses and interface HTL cards. Triggering of the isolated counterpulse circuitry will be outlined. The self-protective aspects of the system employ current sensors to reclose the interrupter if current persists for two milliseconds after counterpulse

  3. Effect of Uphill Flexible Pavements on The Damaging Effect Of Full-Trailer Trucks With Tandem Front Axles

    Directory of Open Access Journals (Sweden)

    Sabah Said Razouki

    2017-08-01

    Full Text Available The effect of traffic on flexible pavements can be expressed in terms of truck equivalence factors. This paper presents a study on the effect of uphill pavements on the damaging effect (truck equivalence factors of two types of full-trailer trucks with tandem front axles. Axle load and geometrical characteristics survey on the two types of full-trailer trucks were carried out for determining the data needed in this study. In addition, uphill slope survey in Kerbala city was done and the data of uphill slope of other Iraqi cities were obtained from previous surveys. The paper reveals that the uphill pavement gradient causes significant increase in truck equivalence factors. In addition, the research reveals that there are many factors affecting the truck equivalence factors on uphill flexible pavements, including the total weight of full-trailer, H/B ratio (height of center of gravity to the wheel base of the truck, magnitude of uphill slope, and the structural number (SN.This work shows the importance of considering the effect of uphill slope in the design of flexible pavements on steep uphill slopes.

  4. CONOCOPHILLIPS FUEL EFFICIENT HIGH-PERFORMANCE(FEHP) SAE 75W90 REAR AXLE GEAR LUBRICANT

    Science.gov (United States)

    This report is on the Environmental Verification Test of a ConocoPhillips real axle gear lubricant to determine whether it could save vehicle fuel. It determined that a verifyable fuel savings could be measured.

  5. MicroPET/CT Imaging of AXL Downregulation by HSP90 Inhibition in Triple-Negative Breast Cancer

    Directory of Open Access Journals (Sweden)

    Wanqin Wang

    2017-01-01

    Full Text Available AXL receptor tyrosine kinase is overexpressed in a number of solid tumor types including triple-negative breast cancer (TNBC. AXL is considered an important regulator of epithelial-to-mesenchymal transition (EMT and a potential therapeutic target for TNBC. In this work, we used microPET/CT with 64Cu-labeled anti-human AXL antibody (64Cu-anti-hAXL to noninvasively interrogate the degradation of AXL in vivo in response to 17-allylamino-17-demethoxygeldanamycin (17-AAG, a potent inhibitor of HSP90. 17-AAG treatment caused significant decline in AXL expression in orthotopic TNBC MDA-MB-231 tumors, inhibited EMT, and delayed tumor growth in vivo, resulting in significant reduction in tumor uptake of 64Cu-anti-hAXL as clearly visualized by microPET/CT. Our data indicate that 64Cu-anti-hAXL can be useful for monitoring anti-AXL therapies and for assessing inhibition of HSP90 molecular chaperone using AXL as a molecular surrogate.

  6. Vibration control of bridge subjected to multi-axle vehicle using multiple tuned mass friction dampers

    Science.gov (United States)

    Pisal, Alka Y.; Jangid, R. S.

    2016-06-01

    The effectiveness of tuned mass friction damper (TMFD) in reducing undesirable resonant response of the bridge subjected to multi-axle vehicular load is investigated. A Taiwan high-speed railway (THSR) bridge subjected to Japanese SKS (Salkesa) train load is considered. The bridge is idealized as a simply supported Euler-Bernoulli beam with uniform properties throughout the length of the bridge, and the train's vehicular load is modeled as a series of moving forces. Simplified model of vehicle, bridge and TMFD system has been considered to derive coupled differential equations of motion which is solved numerically using the Newmark's linear acceleration method. The critical train velocities at which the bridge undergoes resonant vibration are investigated. Response of the bridge is studied for three different arrangements of TMFD systems, namely, TMFD attached at mid-span of the bridge, multiple tuned mass friction dampers (MTMFD) system concentrated at mid-span of the bridge and MTMFD system with distributed TMFD units along the length of the bridge. The optimum parameters of each TMFD system are found out. It has been demonstrated that an optimized MTMFD system concentrated at mid-span of the bridge is more effective than an optimized TMFD at the same place with the same total mass and an optimized MTMFD system having TMFD units distributed along the length of the bridge. However, the distributed MTMFD system is more effective than an optimized TMFD system, provided that TMFD units of MTMFD system are distributed within certain limiting interval and the frequency of TMFD units is appropriately distributed.

  7. Interaction between beam control and rf feedback loops for high Q cavities an heavy beam loading. Revision A

    International Nuclear Information System (INIS)

    Mestha, L.K.; Kwan, C.M.; Yeung, K.S.

    1994-04-01

    An open-loop state space model of all the major low-level rf feedback control loops is derived. The model has control and state variables for fast-cycling machines to apply modern multivariable feedback techniques. A condition is derived to know when exactly we can cross the boundaries between time-varying and time-invariant approaches for a fast-cycling machine like the Low Energy Booster (LEB). The conditions are dependent on the Q of the cavity and the rate at which the frequency changes with time. Apart from capturing the time-variant characteristics, the errors in the magnetic field are accounted in the model to study the effects on synchronization with the Medium Energy Booster (MEB). The control model is useful to study the effects on beam control due to heavy beam loading at high intensities, voltage transients just after injection especially due to time-varying voltages, instability thresholds created by the cavity tuning feedback system, cross coupling between feedback loops with and without direct rf feedback etc. As a special case we have shown that the model agrees with the well known Pedersen model derived for the CERN PS booster. As an application of the model we undertook a detailed study of the cross coupling between the loops by considering all of them at once for varying time, Q and beam intensities. A discussion of the method to identify the coupling is shown. At the end a summary of the identified loop interactions is presented

  8. The effect of heavy- vs. light-load jump squats on the development of strength, power, and speed.

    Science.gov (United States)

    McBride, Jeffrey M; Triplett-McBride, Travis; Davie, Allan; Newton, Robert U

    2002-02-01

    The purpose of this investigation was to examine the effect of an 8-week training program with heavy- vs. light-load jump squats on various physical performance measures and electromyography (EMG). Twenty-six athletic men with varying levels of resistance training experience performed sessions of jump squats with either 30% (JS30, n = 9) or 80% (JS80, n = 10) of their one repetition maximum in the squat (1RM) or served as a control (C, n = 7). An agility test, 20-m sprint, and jump squats with 30% (30J), 55% (55J), and 80% (80J) of their 1RM were performed before and after training. Peak force, peak velocity (PV), peak power (PP), jump height, and average EMG (concentric phase) were calculated for the jumps. There were significant increases in PP and PV in the 30J, 55J, and 80J for the JS30 group (p squats results in increased movement velocity capabilities and that velocity-specific changes in muscle activity may play a key role in this adaptation.

  9. DEVELOPMENT OF AN ARMY STATIONARY AXLE TEST STAND FOR LUBRICANT EFFICIENCY EVALUATION-PART II

    Science.gov (United States)

    2017-01-13

    electric AC motor , and the two outputs of the axle are coupled using speed increasing gear boxes and absorbed by an identically sized AC motor ...work using the stationary axle efficiency test stand was completed using hardware representative of light and medium duty tactical wheeled vehicles ... vehicle results. However for the results to be applicable to real world field use , the driving cycle being replicated should be representative of real

  10. Experimental investigation by laser ultrasonics for high speed train axle diagnostics.

    Science.gov (United States)

    Cavuto, A; Martarelli, M; Pandarese, G; Revel, G M; Tomasini, E P

    2015-01-01

    The present paper demonstrates the applicability of a laser-ultrasonic procedure to improve the performances of train axle ultrasonic inspection. The method exploits an air-coupled ultrasonic probe that detects the ultrasonic waves generated by a high-power pulsed laser. As a result, the measurement chain is completely non-contact, from generation to detection, this making it possible to considerably speed up inspection time and make the set-up more flexible. The main advantage of the technique developed is that it works in thermo-elastic regime and it therefore can be considered as a non-destructive method. The laser-ultrasonic procedure investigated has been applied for the inspection of a real high speed train axle provided by the Italian railway company (Trenitalia), on which typical fatigue defects have been expressly created according to standard specifications. A dedicated test bench has been developed so as to rotate the axle with the angle control and to speed up the inspection of the axle surface. The laser-ultrasonic procedure proposed can be automated and is potentially suitable for regular inspection of train axles. The main achievements of the activity described in this paper are: – the study of the effective applicability of laser-ultrasonics for the diagnostic of train hollow axles with variable sections by means of a numerical FE model, – the carrying out of an automated experiment on a real train axle, – the analysis of the sensitivity to experimental parameters, like laser source – receiving probe distance and receiving probe angular position, – the demonstration that the technique is suitable for the detection of surface defects purposely created on the train axle. Copyright © 2014 Elsevier B.V. All rights reserved.

  11. Cyclic Fracture Toughness of Railway Axle and Mechanisms of its Fatigue Fracture

    Directory of Open Access Journals (Sweden)

    Sorochak Andriy

    2015-06-01

    Full Text Available The main regularities in fatigue fracture of the railway axle material - the OSL steel - are found in this paper. Micromechanisms of fatigue crack propagation are described and systematized, and a physical-mechanical interpretation of the relief morphology at different stages of crack propagation is proposed for fatigue cracks in specimens cut out of the surface, internal and central layers of the axle.

  12. Experimental analysis of ethanol dual-fuel combustion in a heavy-duty diesel engine: An optimisation at low load

    International Nuclear Information System (INIS)

    Pedrozo, Vinícius B.; May, Ian; Dalla Nora, Macklini; Cairns, Alasdair; Zhao, Hua

    2016-01-01

    Highlights: • Dual-fuel combustion offers promising results on a stock heavy-duty diesel engine. • The use of split diesel injections extends the benefits of the dual-fuel mode. • Ethanol–diesel dual-fuel combustion results in high indicated efficiencies. • NOx and soot emissions are significantly reduced. • Combustion efficiency reaches 98% with an ethanol energy ratio of 53%. - Abstract: Conventional diesel combustion produces harmful exhaust emissions which adversely affect the air quality if not controlled by in-cylinder measures and exhaust aftertreatment systems. Dual-fuel combustion can potentially reduce the formation of nitrogen oxides (NOx) and soot which are characteristic of diesel diffusion flame. The in-cylinder blending of different fuels to control the charge reactivity allows for lower local equivalence ratios and temperatures. The use of ethanol, an oxygenated biofuel with high knock resistance and high latent heat of vaporisation, increases the reactivity gradient. In addition, renewable biofuels can provide a sustainable alternative to petroleum-based fuels as well as reduce greenhouse gas emissions. However, ethanol–diesel dual-fuel combustion suffers from poor engine efficiency at low load due to incomplete combustion. Therefore, experimental studies were carried out at 1200 rpm and 0.615 MPa indicated mean effective pressure on a heavy-duty diesel engine. Fuel delivery was in the form of port fuel injection of ethanol and common rail direct injection of diesel. The objective was to improve combustion efficiency, maximise ethanol substitution, and minimise NOx and soot emissions. Ethanol energy fractions up to 69% were explored in conjunction with the effect of different diesel injection strategies on combustion, emissions, and efficiency. Optimisation tests were performed for the optimum fuelling and diesel injection strategy. The resulting effects of exhaust gas recirculation, intake air pressure, and rail pressure were

  13. Algorithm of dynamic stabilization system for a car 4x4 with a link rear axle

    Directory of Open Access Journals (Sweden)

    M. M. Jileikin

    2014-01-01

    Full Text Available The slow development of active safety systems of the automobile all-wheel drive vehicles is the cause of lack of researches in the field of power distribution under the specific conditions of movement. The purpose of work is to develop methods to control a curvilinear motion of 4x4 cars with a link to the rear axle that provides the increase in directional and trajectory stability of the car. The paper analyses the known methods to increase wheeled vehicles movement stability. It also offers a method for power flow redistribution in the transmission of the car 4x4 with a link to the rear axle, providing the increase in directional and trajectory stability of the car.To study the performance and effectiveness of the proposed method a mathematical model of the moving car 4x4 with a link to the rear axle is developed. Simulation methods allowed us to establish the following:1. for car 4x4 with redistribution of torque between the driving axles in the range of 100:0 - 50:50 and with redistribution of torque between the wheels of the rear axle in the range of 0:100 the most effective are the stabilization algorithms used in combination “Lowing power consumption of the engine +Creation of stabilizing the moment due to the redistribution of torque on different wheels", providing the increase in directional and trajectory stability by 12...93%;2. for car 4x4 with redistribution of torque between the driving axles in the range 100:0 - 0:100 and with redistribution of torque between the wheels of the rear axle in the range of 0:100 the best option is a combination of algorithms "Lowing power consumption of the engine + Creation of stabilizing moment due to redistribution of torques on different wheels", providing the increase in directional and trajectory stability by 27...93%.A comparative analysis of algorithms efficiency of dynamic stabilization system operation for two-axle wheeled vehicles depending on the torque redistribution between the driving

  14. Investigation of load transfer efficiency in jointed plain concrete pavements (JPCP using FEM

    Directory of Open Access Journals (Sweden)

    Vahid Sadeghi

    2018-05-01

    Full Text Available Owing to heavy traffic loads, rigid pavements encounter various types of failures at transverse joints during their lifetime. Three-dimensional finite-element method (3D-FEM was used to assess the structural response of jointed concrete pavement under moving tandem axle loads. In this study, 3D FEM was verified using an existing numerical model and field measurement of the concrete slab traversed by a moving truck. This paper also investigated the effects of multiple parameters: material properties, slab geometry, load magnitude and frictional status of the slab and base layer on load transfer efficiency (LTE of the transverse joints. Further study has been done to investigate the slab performance without the dowel bars which occurs when parts of the pavement needed to be repaired using precast slabs. The aggregate interlock between the new slab and the existing slab is simulated by frictional interface. In 3D FEM model, the load transfer efficiency has been improved by increasing the elasticity modules of the concrete slab and the base layer or increasing the slab thickness. This can decrease the joints' deflections, reduces the damages on pavement joints. Removing dowel bars adversely affected the load transfer. Keywords: Concrete pavement, Load transfer, Finite-element method, Dowel bar, Structural behavior

  15. Safety Analysis of 'Older/Aged' Handling and Transportation Equipment for Heavy Loads, Radioactive Waste and Materials in Accordance with German Nuclear Standards KTA 3902, 3903 and 3905

    International Nuclear Information System (INIS)

    Macias, P.; Prucker, E.; Stang, W.

    2006-01-01

    The purpose of this paper is to present a general safety analysis of important handling and transportation processes and their related equipment ('load chains' consisting of cranes, load-bearing equipment and load-attaching points). This project was arranged by the responsible Bavarian ministry for environment, health and consumer protection (StMUGV) in agreement with the power plant operators of all Bavarian nuclear power plants to work out potential safety improvements. The range of the equipment (e.g. reactor building, crane, refuelling machine, load-bearing equipment and load-attaching points) covers the handling and transportation of fuel elements (e. g. with fuel flasks), heavy loads (e.g. reactor pressure vessel closure head, shielding slabs) and radioactive materials and waste (e.g. waste flasks, control elements, fuel channels, structure elements). The handling equipment was subjected to a general safety analysis taking into account the ageing of the equipment and the progress of standards. Compliance with the current valid requirements of the state of science and technology as required by German Atomic Act and particularly of the nuclear safety KTA-standards (3902, 3903 and 3905) was examined. The higher protection aims 'safe handling and transportation of heavy loads and safe handling of radioactive materials and waste' of the whole analysis are to avoid a criticality accident, the release of radioactivity and inadmissible effects on important technical equipment and buildings. The scope of the analysis was to check whether these protection aims were fulfilled for all important technical handling and transportation processes. In particularly the design and manufacturing of the components and the regulations of the handling itself were examined. (authors)

  16. Tolerance Limit for Trucks with Excess Load in Transport Regulation in Indonesia

    Directory of Open Access Journals (Sweden)

    Sigit Hadiwardoyo

    2012-05-01

    Full Text Available Reliability of a road is mandatory since damaged will impede the traffic. Destruction is caused by various factors; one of the most important factors is excess load. Overload may give the load of each axle of a vehicle exceeds the determined standard. This condition occurs in trucks exceeding the load limit. In designing the structure of a road based on the method of Directorate General of Highways Ministry of Public Works of the Republic of Indonesia, axle load calculated in equivalent-number, or known as equivalent axle load (EAL, of 8.16 tons of standard axle. Total equivalent-number over the service life is defined as cumulative equivalent standard axle load (CESA. Due to traffic volume exceeding the volume forecast or, in other words there is an excessive load of traffic, it will make CESA achieved faster than planned. This excessive load in Indonesia, however, has been  considered as a factor of environmental condition, so there is a need to introduce a correction factor for EAL as high as 20-25% in the process of designing flexible and rigid pavement so as to reduce early damage.

  17. Nonlinear dynamic response of a 'flexible-and-heavy' printed circuit board (PCB) to an impact load applied to its support contour

    International Nuclear Information System (INIS)

    Suhir, E; Vujosevic, M; Reinikainen, T

    2009-01-01

    Based on the developed simple and physically meaningful analytical ('mathematical') stress model, we evaluate some major parameters (amplitude, frequency, maximum acceleration, stresses and strains) of the response of a 'flexible-and-heavy' square simply supported printed circuit board (PCB) to an impact drop load applied to its support contour. The analysis is restricted to the first mode of vibrations and is carried out in application to the PCB design employed in an advanced accelerated test setup (test vehicle). This setup is aimed at the assessment of the performance, in accelerated test conditions on the board level, of packaging materials (and, first of all, BGA solder joint interconnections) subjected to dynamic (drop or shock) loading. It is anticipated that heavy masses could be mounted on the PCB to accelerate its dynamic response to an impact load. These masses are expected to be small in size, so that while changing the total mass of the board and generating significant inertia forces, they do not affect the board's flexural rigidity or its stiffness with respect to the in-plane loading. The PCB's contour is considered non-deformable, which is indeed the case in many practical situations. This circumstance, if the drop height and/or the induced inertia forces are significant, leads to elevated in-plane ('membrane') stresses in the PCB and, as a result of that, to the nonlinear response of the board to the impact load: the relationship between the magnitude of the load (determined by the initial impact velocity) and the induced PCB deflections becomes geometrically nonlinear, with a rigid cubic characteristic of the restoring force. The carried out numerical example, although reflects the characteristics of the PCB and loading conditions in an actual experimental setup, is merely an illustration of the general concept and is intended to demonstrate the abilities of the suggested method. Predictions based on this method agree well with the finite element

  18. Dynamic Characteristics of a New Machine for Fatigue Testing of Railway Axles – Part 2

    Directory of Open Access Journals (Sweden)

    Karel FRYDRÝŠEK

    2012-06-01

    Full Text Available There were done some proposal calculations for a new testing machine. This new testing machine is determined for a dynamic fatigue testing of railway axles. The railway axles are subjected to bending and rotation (centrifugal effects. For the right proposition of a new machine is very important to know the basic dynamic characteristics of whole system. These dynamic characteristics are solved via FEM (MSC.Marc/Mentat software in combination with SBRA (Simulation-Based Reliability Assessment Method (probabilistic Monte Carlo approach, Anthill and Python software. The proposed dimensions and springs of a new machine for fatigue testing of railway axles were used for manufacturing. Application of the SBRA method connected with FEM in these areas is a new and innovative trend in mechanics. This paper is continuation of former work (i.e. easier deterministic approach already presented in this journal in 2007.

  19. Diluted Operation of a Heavy-Duty Natural Gas Engine - Aiming at Improved Effciency, Emission and Maximum Load

    OpenAIRE

    Kaiadi, Mehrzad

    2011-01-01

    Most heavy-duty engines are diesel operated. Severe emission regulations, high fuel prices, high technology costs (e.g. catalysts, fuel injection systems) and unsustainably in supplying fuel are enough reasons to convenience engine developers to explore alternative technologies or fuels. Using natural gas/biogas can be a very good alternative due to the attractive fuel properties regarding emission reduction and engine operation. Heavy-duty diesel engines can be easily converted for natur...

  20. Discussion about effecting of stiffener in four bolts in a row end plate connection for long span and heavy load steel structures in Vietnam

    Science.gov (United States)

    Huong, Khang T.; Nguyen, Cung H.

    2018-04-01

    Nowadays, steel structure industry in Vietnam is in strong development. The construction of steel structure becomes larger span and heavier load. The issue spawned a number of issues arise from optimizing connections. Typical of steel connections in prefabricated steel structure that is an end plate (face plate) bolted connection. When the connection carried a heavy load, then the number of bolts is required much more. Increasing the number of rows bolts will less effective because can still not enough strength requirements, the bolts in row near rotational center will level arm reduction, then it cannot carry heavy loads. The current solution is doing multiple bolts in a row. Current standards such as EN [1], AISC [2] are no specific guidelines for calculating the connection four bolts in a row that primarily assumes the way works like a T-stub of the two bolts a row. Some articles studied T-stub four bolts in a row [3], [4], [5], [6] by component method but it has some components which weren’t considered. In this paper, in order to provide a contribution to improve the T-stub four bolts in a row, the stiffener component in T-stub will be added and compared with T-stub without stiffener by the finite element model to demonstrate effectiveness in reducing stress and displacement of T-stub. It gives ideas for the economic design of four bolts in a row end plate connection in Vietnam for future.

  1. Two lighter than air systems in opposing flight regimes: An unmanned short haul, heavy load transport balloon and a manned, light payload airship

    Science.gov (United States)

    Pohl, R. A.

    1975-01-01

    Lighter Than Air vehicles are generally defined or categorized by the shape of the balloon, payload capacity and operational flight regime. Two balloon systems that are classed as being in opposite categories are described. One is a cable guided, helium filled, short haul, heavy load transport Lighter Than Air system with a natural shaped envelope. The other is a manned, aerodynamic shaped airship which utilizes hot air as the buoyancy medium and is in the light payload class. While the airship is in the design/fabrication phase with flight tests scheduled for the latter part of 1974, the transport balloon system has been operational for some eight years.

  2. Crack closure in near-threshold fatigue crack propagation in railway axle steel EA4T

    Czech Academy of Sciences Publication Activity Database

    Pokorný, Pavel; Vojtek, Tomáš; Náhlík, Luboš; Hutař, Pavel

    2017-01-01

    Roč. 185, NOV (2017), s. 2-19 ISSN 0013-7944 R&D Projects: GA MŠk(CZ) LQ1601 Institutional support: RVO:68081723 Keywords : Fatigue crack propagation * crack closure * EA4T * Railway axle Subject RIV: JL - Materials Fatigue, Friction Mechanics OBOR OECD: Audio engineering , reliability analysis Impact factor: 2.151, year: 2016

  3. On Optimizing Steering Performance of Multi-axle Vehicle Based on Driving Force Control

    Directory of Open Access Journals (Sweden)

    Wu Zhicheng

    2017-01-01

    Full Text Available The steering performance of multi-axle vehicle with independent driving system is affected by the distribution of the wheel driving force. A nonlinear vehicle dynamics model including magic formula tire model for describing 11 DoF four-axle vehicle with dual-front-axle-steering (DFAS system was presented. The influence of different driving force distribution scheme on the steering performance of the vehicle was analyzed. A control strategy for improving the steady response and transient response of the vehicle steering is proposed. The results show: For the steady response, setting different drive force for internal and external wheels according to the actual steering characteristics of the vehicle can effectively improve its steering characteristics; For the transient response, adopting the zero sideslip angle control strategy and using the PID control algorithm to control the driving force of the outside wheel of tear-two-axle, under angle step input, the vehicle sideslip angle can quickly stabilize to 0 and yaw rate also significantly decreases.

  4. Performance of Single Axle Tractors in the Semi-Arid Central Part of ...

    African Journals Online (AJOL)

    user1

    Performance evaluation of three single axle tractors namely Dongfeng15 hp and 12 hp ... On average the agricultural sector accounts for 42.9% gross domestic product and ..... a and b are constant(coefficient) with (+) or (-) sign shown table ...

  5. Dynamics of two-axle railway freight wagons with UIC standard suspension

    DEFF Research Database (Denmark)

    Hoffmann, Mark; True, Hans

    2006-01-01

    The dynamics of two different two-axle railway freight wagons is investigated theoretically and compared. Fully nonlinear models are considered. The hysteresis from dry friction and the effect of impacts between elements of the suspension are included. Bifurcation diagrams are shown in order...

  6. Wheeled Vehicle Drive Lines, Axles, and Suspension Systems. Military Curriculum Materials for Vocational and Technical Education.

    Science.gov (United States)

    Army Ordnance Center and School, Aberdeen Proving Ground, MD.

    This course is one of several subcourses that make up the entire Army correspondence course on wheeled vehicle maintenance. The subcourse is designed to provide the student with information about the operation, malfunction diagnosis, maintenance, and repair of wheeled vehicle drive lines, axles, and suspension systems. It provides the basic…

  7. The dynamics of European two-axle railway freight wagons with UIC standard suspension

    DEFF Research Database (Denmark)

    Hoffmann, Mark; True, Hans

    2008-01-01

    The dynamics of two-axle railway freight wagons with the UIC standard Suspension is investigated theoretically and the dynamic behaviour is explained. Fully nonlinear models are considered. The hysteresis from dry friction and the effect of impacts between elements of the suspension are included...

  8. EFFECTS OF ENGINE SPEED AND ACCESSORY LOAD ON IDLING EMISSIONS FROM HEAVY-DUTY DIESEL TRUCK ENGINES

    Science.gov (United States)

    A nontrivial portion of heavy-duty vehicle emissions of nitrogen oxides (NOx) and particulate matter (PM) occurs during idling. Regulators and the environmental community are interested in curtailing truck idling emissions, but current emissions models do not characterize them ac...

  9. Determination of Heavy Metals Pollution Load Index in Sediments and Aquatic Plant (Nasturtium microphyllum in Bashar River, Yasuj

    Directory of Open Access Journals (Sweden)

    Samar Mortazavi

    2018-03-01

    Conclusion: According to the results, the pollution and ecological risk of metals in the region is low evaluated. The results of this study confirm the use of Nasturtium microphyllum as a heavy metals accumulation species and a suitable indicator for their biomonitoring.

  10. Effects of biodiesel, engine load and diesel particulate filter on nonvolatile particle number size distributions in heavy-duty diesel engine exhaust.

    Science.gov (United States)

    Young, Li-Hao; Liou, Yi-Jyun; Cheng, Man-Ting; Lu, Jau-Huai; Yang, Hsi-Hsien; Tsai, Ying I; Wang, Lin-Chi; Chen, Chung-Bang; Lai, Jim-Shoung

    2012-01-15

    Diesel engine exhaust contains large numbers of submicrometer particles that degrade air quality and human health. This study examines the number emission characteristics of 10-1000 nm nonvolatile particles from a heavy-duty diesel engine, operating with various waste cooking oil biodiesel blends (B2, B10 and B20), engine loads (0%, 25%, 50% and 75%) and a diesel oxidation catalyst plus diesel particulate filter (DOC+DPF) under steady modes. For a given load, the total particle number concentrations (N(TOT)) decrease slightly, while the mode diameters show negligible changes with increasing biodiesel blends. For a given biodiesel blend, both the N(TOT) and mode diameters increase modestly with increasing load of above 25%. The N(TOT) at idle are highest and their size distributions are strongly affected by condensation and possible nucleation of semivolatile materials. Nonvolatile cores of diameters less than 16 nm are only observed at idle mode. The DOC+DPF shows remarkable filtration efficiency for both the core and soot particles, irrespective of the biodiesel blend and engine load under study. The N(TOT) post the DOC+DPF are comparable to typical ambient levels of ≈ 10(4)cm(-3). This implies that, without concurrent reductions of semivolatile materials, the formation of semivolatile nucleation mode particles post the after treatment is highly favored. Copyright © 2011 Elsevier B.V. All rights reserved.

  11. A novel reusable nanocomposite for complete removal of dyes, heavy metals and microbial load from water based on nanocellulose and silver nano-embedded pebbles.

    Science.gov (United States)

    Suman; Kardam, Abhishek; Gera, Meeta; Jain, V K

    2015-01-01

    The present work proposed a nanocellulose (NC)-silver nanoparticles (AgNPs) embedded pebbles-based composite material as a novel reusable cost-effective water purification device for complete removal of dyes, heavy metals and microbes. NC was prepared using acid hydrolysis of cellulose. The AgNPs were generated in situ using glucose and embedded within the porous concrete pebbles by the technique of inter-diffusion of ion, providing a very strong binding of nanoparticles within the porous pebbles and thus preventing any nanomaterials leaching. Fabrication of a continual running water purifier was achieved by making different layering of NC and Ag nano-embedded pebbles in a glass column. The water purifier exhibited not only excellent dye and heavy metal adsorption capacity, but also long-term antibacterial activity against pathogenic and non-pathogenic bacterial strains. The adsorption mainly occurred through electrostatic interaction and pore diffusion also contributed to the process. The bed column purifier has shown 99.48% Pb(II) and 98.30% Cr(III) removal efficiency along with 99% decontamination of microbial load at an optimum working pH of 6.0. The high adsorption capacity and reusability, with complete removal of dyes, heavy metals and Escherichia coli from the simulated contaminated water of composite material, will provide new opportunities to develop a cost-effective and eco-friendly water purifier for commercial application.

  12. Optimum Design and Performance of Porous Concrete for Heavy-Load Traffic Pavement in Cold and Heavy Rainfall Region of NE China

    Directory of Open Access Journals (Sweden)

    Ailing Yao

    2018-01-01

    Full Text Available The aim of the study was to solve the problem of drainage stability of pavement base in cold and Cloudburst area. With porous concrete as the research object, an optimum design of porous concrete was determined using a step filling and orthogonal test method, and the relationship between the porosity and the connected porosity of the porous concrete was analyzed. Furthermore, drainage performance and frost resistance of the pavement, compressive strength of the porous concrete, bending strength, and compressive elastic modulus were studied. The results show that the effects of water-cement ratio on the strength of porous concrete based on the step filling method are the most significant. In addition, the connected porosity and goal porosity have a good linear relationship; that is, the drainage performance increases with the increase in connected porosity, whereas the frost resistance, compressive strength, flexural tensile strength, and compressive elastic modulus decrease with the increase in connected porosity. Based on an engineering project in Inner Mongolia (in China, it was shown that porous concrete with a goal porosity of 15% used as a pavement base could meet the requirements of cold weather, showers, and heavy traffic.

  13. Development Of Automatic Axle Drop System For Trucks With Mechanical Suspension

    OpenAIRE

    Acar, Osman Uğur

    2013-01-01

    In our country and all over the world, highway has a great portion on transportation. Highway is an expensive investment and being protected is important with regard to security and comfort. Deterioration of highways leads to loss of comfort and safe, besides its economical cost. The vehicles loadaed inaccurately and/or transporting heavy load are remarkable factor over deterioration of highways. Overloading these vehicles lead to excessive pressure over unit area of the road and eventually d...

  14. A method for apportionment of natural and anthropogenic contributions to heavy metal loadings in the surface soils across large-scale regions.

    Science.gov (United States)

    Hu, Yuanan; Cheng, Hefa

    2016-07-01

    Quantification of the contributions from anthropogenic sources to soil heavy metal loadings on regional scales is challenging because of the heterogeneity of soil parent materials and high variability of anthropogenic inputs, especially for the species that are primarily of lithogenic origin. To this end, we developed a novel method for apportioning the contributions of natural and anthropogenic sources by combining sequential extraction and stochastic modeling, and applied it to investigate the heavy metal pollution in the surface soils of the Pearl River Delta (PRD) in southern China. On the average, 45-86% of Zn, Cu, Pb, and Cd were present in the acid soluble, reducible, and oxidizable fractions of the surface soils, while only 12-24% of Ni, Cr, and As were partitioned in these fractions. The anthropogenic contributions to the heavy metals in the non-residual fractions, even the ones dominated by natural sources, could be identified and quantified by conditional inference trees. Combination of sequential extraction, Kriging interpolation, and stochastic modeling reveals that approximately 10, 39, 6.2, 28, 7.1, 15, and 46% of the As, Cd, Cr, Cu, Ni, Pb, and Zn, respectively, in the surface soils of the PRD were contributed by anthropogenic sources. These results were in general agreements with those obtained through subtraction of regional soil metal background from total loadings, and the soil metal inputs through atmospheric deposition as well. In the non-residual fractions of the surface soils, the anthropogenic contributions to As, Cd, Cr, Cu, Ni, Pb, and Zn, were 48, 42, 50, 51, 49, 24, and 70%, respectively. Copyright © 2016 Elsevier Ltd. All rights reserved.

  15. Assessment of heavy metal load in chub liver (Cyprinidae – Leuciscus cephalus from the Nišava River (Serbia

    Directory of Open Access Journals (Sweden)

    Jovanović, B.

    2011-09-01

    Full Text Available The Nišava River plays an important role as the source for both drinking water and agricultural irrigation due to its hydrological and geomorphological characteristics as the largest river in the region of southeast Serbia. In this study we used the liver of the chub (Leiciscus cephalus as a tool for biomonitoring heavy metal accumulation along the river. Chub specimens were sampled from two localities (one at the border with Bulgaria and a second in the city of Niš. Concentrations were estimated for six heavy metals (iron, cadmium, copper, zinc, lead and manganese in chub liver. Low bioconcentration level was observed for most of the metals and the concentrations corresponded to the nominal concentration in livers of fish inhabiting metal unpolluted streams and rivers. However, cadmium concentration in the chub liver exceeded 0.5 mg kg-1, a several hundred folds increase from nominal concentration indicating a potential toxic exposure of the fish and of the stream ecosystem to this heavy metal. Hepatosomatic indices were calculated and tested for the impact of metal concentrations on liver size. A decrease of the hepatic index was observed in fish with higher cadmium concentration, suggesting a possible impact on the health of the chub population in the Nišava River.

  16. Departure fuel loads in time-minimizing migrating birds can be explained by the energy costs of being heavy

    NARCIS (Netherlands)

    Klaassen, M.R.J.; Lindstrom, A.

    1996-01-01

    Lindstrom & Alerstam (1992 Am. Nat. 140, 477-491) presented a model that predicts optimal departure fuel loads as a function of the rate of fuel deposition in time-minimizing migrants. The basis of the model is that the coverable distance per unit of fuel deposited, diminishes with increasing fuel

  17. Effects of biodiesel, engine load and diesel particulate filter on nonvolatile particle number size distributions in heavy-duty diesel engine exhaust

    Energy Technology Data Exchange (ETDEWEB)

    Young, Li-Hao, E-mail: lhy@mail.cmu.edu.tw [Department of Occupational Safety and Health, China Medical University, 91, Hsueh-Shih Road, Taichung 40402, Taiwan (China); Liou, Yi-Jyun [Department of Occupational Safety and Health, China Medical University, 91, Hsueh-Shih Road, Taichung 40402, Taiwan (China); Cheng, Man-Ting [Department of Environmental Engineering, National Chung Hsing University, 250, Kuo-Kuang Road, Taichung 40254, Taiwan (China); Lu, Jau-Huai [Department of Mechanical Engineering, National Chung Hsing University, 250, Kuo-Kuang Road, Taichung 40254, Taiwan (China); Yang, Hsi-Hsien [Department of Environmental Engineering and Management, Chaoyang University of Technology, 168, Jifeng E. Road, Taichung 41349, Taiwan (China); Tsai, Ying I. [Department of Environmental Engineering and Science, Chia Nan University of Pharmacy and Science, 60, Sec. 1, Erh-Jen Road, Tainan 71710, Taiwan (China); Wang, Lin-Chi [Department of Chemical and Materials Engineering, Cheng Shiu University, 840, Chengcing Road, Kaohsiung 83347, Taiwan (China); Chen, Chung-Bang [Fuel Quality and Engine Performance Research, Refining and Manufacturing Research Institute, Chinese Petroleum Corporation, 217, Minsheng S. Road, Chiayi 60036, Taiwan (China); Lai, Jim-Shoung [Department of Occupational Safety and Health, China Medical University, 91, Hsueh-Shih Road, Taichung 40402, Taiwan (China)

    2012-01-15

    Highlights: Black-Right-Pointing-Pointer The effects of waste cooking oil biodiesel, engine load and DOC + DPF on nonvolatile particle size distributions in HDDE exhaust. Black-Right-Pointing-Pointer Increasing biodiesel blends cause slight decreases in the total particle number concentrations and negligible changes in size distributions. Black-Right-Pointing-Pointer Increasing load results in modest increases in both the total particle number concentrations and sizes. Black-Right-Pointing-Pointer The effects of semivolatile materials are strongest at idle, during which nonvolatile cores <16 nm were observed. Black-Right-Pointing-Pointer The DOC + DPF shows remarkable filtration efficiency for both the core and soot particles, irrespective of biodiesel blend and load. - Abstract: Diesel engine exhaust contains large numbers of submicrometer particles that degrade air quality and human health. This study examines the number emission characteristics of 10-1000 nm nonvolatile particles from a heavy-duty diesel engine, operating with various waste cooking oil biodiesel blends (B2, B10 and B20), engine loads (0%, 25%, 50% and 75%) and a diesel oxidation catalyst plus diesel particulate filter (DOC + DPF) under steady modes. For a given load, the total particle number concentrations (N{sub TOT}) decrease slightly, while the mode diameters show negligible changes with increasing biodiesel blends. For a given biodiesel blend, both the N{sub TOT} and mode diameters increase modestly with increasing load of above 25%. The N{sub TOT} at idle are highest and their size distributions are strongly affected by condensation and possible nucleation of semivolatile materials. Nonvolatile cores of diameters less than 16 nm are only observed at idle mode. The DOC + DPF shows remarkable filtration efficiency for both the core and soot particles, irrespective of the biodiesel blend and engine load under study. The N{sub TOT} post the DOC + DPF are comparable to typical ambient levels of

  18. Adsorptive removal of heavy metals from water using sodium titanate nanofibres loaded onto GAC in fixed-bed columns.

    Science.gov (United States)

    Sounthararajah, D P; Loganathan, P; Kandasamy, J; Vigneswaran, S

    2015-04-28

    Heavy metals are serious pollutants in aquatic environments. A study was undertaken to remove Cu, Cd, Ni, Pb and Zn individually (single metal system) and together (mixed metals system) from water by adsorption onto a sodium titanate nanofibrous material. Langmuir adsorption capacities (mg/g) at 10(-3)M NaNO3 ionic strength in the single metal system were 60, 83, 115 and 149 for Ni, Zn, Cu, and Cd, respectively, at pH 6.5 and 250 for Pb at pH 4.0. In the mixed metals system they decreased at high metals concentrations. In column experiments with 4% titanate material and 96% granular activated carbon (w/w) mixture at pH 5.0, the metals breakthrough times and adsorption capacities (for both single and mixed metals systems) decreased in the order Pb>Cd, Cu>Zn>Ni within 266 bed volumes. The amounts adsorbed were up to 82 times higher depending on the metal in the granular activated carbon+titanate column than in the granular activated carbon column. The study showed that the titanate material has high potential for removing heavy metals from polluted water when used with granular activated carbon at a very low proportion in fixed-bed columns. Copyright © 2015 Elsevier B.V. All rights reserved.

  19. Loss of the receptor tyrosine kinase Axl leads to enhanced inflammation in the CNS and delayed removal of myelin debris during Experimental Autoimmune Encephalomyelitis

    Directory of Open Access Journals (Sweden)

    Prieto Anne L

    2011-05-01

    Full Text Available Abstract Background Axl, together with Tyro3 and Mer, constitute the TAM family of receptor tyrosine kinases. In the nervous system, Axl and its ligand Growth-arrest-specific protein 6 (Gas6 are expressed on multiple cell types. Axl functions in dampening the immune response, regulating cytokine secretion, clearing apoptotic cells and debris, and maintaining cell survival. Axl is upregulated in various disease states, such as in the cuprizone toxicity-induced model of demyelination and in multiple sclerosis (MS lesions, suggesting that it plays a role in disease pathogenesis. To test for this, we studied the susceptibility of Axl-/- mice to experimental autoimmune encephalomyelitis (EAE, an animal model for multiple sclerosis. Methods WT and Axl-/- mice were immunized with myelin oligodendrocyte glycoprotein (MOG35-55 peptide emulsified in complete Freund's adjuvant and injected with pertussis toxin on day 0 and day 2. Mice were monitored daily for clinical signs of disease and analyzed for pathology during the acute phase of disease. Immunological responses were monitored by flow cytometry, cytokine analysis and proliferation assays. Results Axl-/- mice had a significantly more severe acute phase of EAE than WT mice. Axl-/- mice had more spinal cord lesions with larger inflammatory cuffs, more demyelination, and more axonal damage than WT mice during EAE. Strikingly, lesions in Axl-/- mice had more intense Oil-Red-O staining indicative of inefficient clearance of myelin debris. Fewer activated microglia/macrophages (Iba1+ were found in and/or surrounding lesions in Axl-/- mice relative to WT mice. In contrast, no significant differences were noted in immune cell responses between naïve and sensitized animals. Conclusions These data show that Axl alleviates EAE disease progression and suggests that in EAE Axl functions in the recruitment of microglia/macrophages and in the clearance of debris following demyelination. In addition, these data

  20. Comparison of heavy metal loads in stormwater runoff from major and minor urban roads using pollutant yield rating curves

    International Nuclear Information System (INIS)

    Davis, Brett; Birch, Gavin

    2010-01-01

    Trace metal export by stormwater runoff from a major road and local street in urban Sydney, Australia, is compared using pollutant yield rating curves derived from intensive sampling data. The event loads of copper, lead and zinc are well approximated by logarithmic relationships with respect to total event discharge owing to the reliable appearance of a first flush in pollutant mass loading from urban roads. Comparisons of the yield rating curves for these three metals show that copper and zinc export rates from the local street are comparable with that of the major road, while lead export from the local street is much higher, despite a 45-fold difference in traffic volume. The yield rating curve approach allows problematic environmental data to be presented in a simple yet meaningful manner with less information loss. - A simple method for representing data onroad runoff pollution allows comparisons among dissimilar sites and could form the basis for a pollution database.

  1. Fuel and Core Design Options to Overcome the Heavy Metal Loading Limit and Improve Performance and Safety of Liquid Salt Cooled Reactors

    Energy Technology Data Exchange (ETDEWEB)

    Petrovic, Bojan [Georgia Inst. of Technology, Atlanta, GA (United States); Maldonado, Ivan [Univ. of Tennessee, Knoxville, TN (United States)

    2016-04-14

    The research performed in this project addressed the issue of low heavy metal loading and the resulting reduced cycle length with increased refueling frequency, inherent to all FHR designs with solid, non-movable fuel based on TRISO particles. Studies performed here focused on AHTR type of reactor design with plate (“plank”) fuel. Proposal to FY12 NEUP entitled “Fuel and Core Design Options to Overcome the Heavy Metal Loading Limit and Improve Performance and Safety of Liquid Salt Cooled Reactors” was selected for award, and the 3-year project started in August 2012. A 4-month NCE was granted and the project completed on December 31, 2015. The project was performed by Georgia Tech (Prof. Bojan Petrovic, PI) and University of Tennessee (Prof. Ivan Maldonado, Co-PI), with a total funding of $758,000 over 3 years. In addition to two Co-PIs, the project directly engaged 6 graduate students (at doctoral or MS level) and 2 postdoctoral researchers. Additionally, through senior design projects and graduate advanced design projects, another 23 undergraduate and 12 graduate students were exposed to and trained in the salt reactor technology. We see this as one of the important indicators of the project’s success and effectiveness. In the process, 1 journal article was published (with 3 journal articles in preparation), together with 8 peer-reviewed full conference papers, 8 peer-reviewed extended abstracts, as well as 1 doctoral dissertation and 2 master theses. The work included both development of models and methodologies needed to adequately analyze this type of reactor, fuel, and its fuel cycle, as well as extensive analyses and optimization of the fuel and core design.

  2. Fuel and Core Design Options to Overcome the Heavy Metal Loading Limit and Improve Performance and Safety of Liquid Salt Cooled Reactors

    International Nuclear Information System (INIS)

    Petrovic, Bojan; Maldonado, Ivan

    2016-01-01

    The research performed in this project addressed the issue of low heavy metal loading and the resulting reduced cycle length with increased refueling frequency, inherent to all FHR designs with solid, non-movable fuel based on TRISO particles. Studies performed here focused on AHTR type of reactor design with plate ('plank') fuel. Proposal to FY12 NEUP entitled 'Fuel and Core Design Options to Overcome the Heavy Metal Loading Limit and Improve Performance and Safety of Liquid Salt Cooled Reactors' was selected for award, and the 3-year project started in August 2012. A 4-month NCE was granted and the project completed on December 31, 2015. The project was performed by Georgia Tech (Prof. Bojan Petrovic, PI) and University of Tennessee (Prof. Ivan Maldonado, Co-PI), with a total funding of $758,000 over 3 years. In addition to two Co-PIs, the project directly engaged 6 graduate students (at doctoral or MS level) and 2 postdoctoral researchers. Additionally, through senior design projects and graduate advanced design projects, another 23 undergraduate and 12 graduate students were exposed to and trained in the salt reactor technology. We see this as one of the important indicators of the project's success and effectiveness. In the process, 1 journal article was published (with 3 journal articles in preparation), together with 8 peer-reviewed full conference papers, 8 peer-reviewed extended abstracts, as well as 1 doctoral dissertation and 2 master theses. The work included both development of models and methodologies needed to adequately analyze this type of reactor, fuel, and its fuel cycle, as well as extensive analyses and optimization of the fuel and core design.

  3. Adsorption of heavy metals from aqueous solution by UV-mutant Bacillus subtilis loaded on biochars derived from different stock materials.

    Science.gov (United States)

    Wang, Ting; Sun, Hongwen; Ren, Xinhao; Li, Bing; Mao, Hongjun

    2018-02-01

    Two kinds of biochars, one derived from corn straw (CBC) and one from pig manure (PBC), were used as the carriers of a bacterium (B38) to adsorb heavy metals in solution. CBC exhibited high affinity to Hg(II), while PBC showed large adsorption capacity of Pb(II). After loading with B38, the sorption capacity of the co-sorbents were enhanced for Pb(II), but weakened for Hg(II). In a binary system, the overall adsorption capacity to Hg-Pb (CBC+B38, 136.7mg/g; PBC+B38, 181.3mg/g) on co-sorbents was equal to the sum of the single-component values for Hg(II) and Pb(II). Electrostatic interactions and precipitation are the major mechanisms in the adsorption of Hg(II). In contrast, cation-π interactions and precipitation were involved in the sorption process of Pb(II). Moreover, the sorption sites of Hg(II) and Pb(II) partially overlapped on the biochar surface, but were different on co-sorbents. Hence, the co-sorbents have an advantage over the biochar alone in the removal of heavy metal mixtures. Copyright © 2017 Elsevier Inc. All rights reserved.

  4. A cross sectional study of the relationship between the exposure of pregnant women to military attacks in 2014 in Gaza and the load of heavy metal contaminants in the hair of mothers and newborns.

    Science.gov (United States)

    Manduca, Paola; Diab, Safwat Y; Qouta, Samir R; Albarqouni, Nabil Ma; Punamaki, Raiija-Leena

    2017-08-02

    Metal contamination of humans in war areas has rarely been investigated. Weaponry's heavy metals become environmentally stable war remnants and accumulate in living things. They also pose health risks in terms of prenatal intake, with potential long term risks for reproductive and children's health. We studied the contribution of military attacks to the load of 23 metals in the hair of Palestinian women in the Gaza Strip, who were pregnant at the time of the military attacks in 2014, and their newborns. We compared the metal load in the mothers with values for adult hair from outside the war area (RHS) as the reference. We investigated heavy metals trans-passing in utero, and assessed if the heavy metal intake could derive from sources unrelated to the war. Cross sectional study. Cross sectional convenience sample of 502 mothers delivering in the Gaza Strip and their newborns. Measure of the load of heavy metals in mother and newborn hair by inductively coupled plasma-mass spectrometry (ICP-MS). Comparison of metal loads with the reference RHS, between groups with different exposures to attacks and house/agriculture chemicals, and between mothers and newborns. Data for birth registry and for exposures to war and other known risk factors were obtained at interview with the mothers. Photographic documentation of damage from military attacks was obtained. The whole cross sectional convenience sample had a significantly higher load of heavy metals than the reference RHS. Women exposed to military attacks had a significantly higher load of heavy metals than those not exposed; the load in newborns correlated positively with the mothers' load. No significant difference was found between users/non-users of house/agriculture chemicals. No other known confounder was identified. High heavy metal loads in mothers, reflected in those of their newborns, were associated with exposure to military attacks, posing a risk of immediate and long term negative outcomes for pregnancy and

  5. The Axl kinase domain in complex with a macrocyclic inhibitor offers first structural insights into an active TAM receptor kinase.

    Science.gov (United States)

    Gajiwala, Ketan S; Grodsky, Neil; Bolaños, Ben; Feng, Junli; Ferre, RoseAnn; Timofeevski, Sergei; Xu, Meirong; Murray, Brion W; Johnson, Ted W; Stewart, Al

    2017-09-22

    The receptor tyrosine kinase family consisting of Tyro3, Axl, and Mer (TAM) is one of the most recently identified receptor tyrosine kinase families. TAM receptors are up-regulated postnatally and maintained at high levels in adults. They all play an important role in immunity, but Axl has also been implicated in cancer and therefore is a target in the discovery and development of novel therapeutics. However, of the three members of the TAM family, the Axl kinase domain is the only one that has so far eluded structure determination. To this end, using differential scanning fluorimetry and hydrogen-deuterium exchange mass spectrometry, we show here that a lower stability and greater dynamic nature of the Axl kinase domain may account for its poor crystallizability. We present the first structural characterization of the Axl kinase domain in complex with a small-molecule macrocyclic inhibitor. The Axl crystal structure revealed two distinct conformational states of the enzyme, providing a first glimpse of what an active TAM receptor kinase may look like and suggesting a potential role for the juxtamembrane region in enzyme activity. We noted that the ATP/inhibitor-binding sites of the TAM members closely resemble each other, posing a challenge for the design of a selective inhibitor. We propose that the differences in the conformational dynamics among the TAM family members could potentially be exploited to achieve inhibitor selectivity for targeted receptors. © 2017 by The American Society for Biochemistry and Molecular Biology, Inc.

  6. Contaminatiom of sediment loads of the Waterwork Ružín I. by heavy metals in relation to mining sludge basins

    Directory of Open Access Journals (Sweden)

    Brehuv Ján

    2000-09-01

    Full Text Available From the results of monitoring of the quality of surface water in the Hnilec and Hornád rivers and their tributaries followed that in addition to industrial toxic substances, it were the heavy metals from localities of former and still continuing mining, treatment or metallurgic activities that significantly influence a long-term polution. The subsequent project showed a need to monitor the impact of anthropogenic activity, namely on the Waterwork (VD Ružín I. It was a task of our institution to judge the quality of sediment loads in the waterwork area.The first samples of sediment loads of the waterwork were taken in 1994. The sampling process then continued on the same places in following years. The special methods of sampling of sediment loads (sediments from the waterwork bed were worked out depending on the locality of sampling. The total analysis of obtained air-dried samples was caried out using the AAS method. The heavy metals were also analysed. In the consent with standards and requiremnts of the co-ordinator of task, the sediment deposits were assessed in consent with Decree of the Ministry of Land Managment of the Slovak Republik 531/1994-540 on the highest admissible values of harmful subsatances in land.Comparing the results of sampling we have observed that the critical values have been achieved in case of Cu. Its high values were found in the branches of Hnilec and Hornád rivers, as well sa in the branch of Opátka. The increased contents of Co are in Beliansky and Opatsky branches, at the inflow of Hnilec and Folkmarsky brook into the waterwork. The position of Hg is interesting, as it was the main contaminating element of The Hornad river and its sediments in the past. Hg is not currently present at significant quantities.The vertical sampling was also carried out in the course of research. It was proved that the content of contaminating elements in sediments of waterwork originates in the industrial activity perfomed 15

  7. Influence of Initial Inclined Surface Crack on Estimated Residual Fatigue Lifetime of Railway Axle

    Czech Academy of Sciences Publication Activity Database

    Náhlík, Luboš; Pokorný, Pavel; Ševčík, Martin; Hutař, Pavel

    2016-01-01

    Roč. 7, č. 4 (2016), č. článku 1640007. ISSN 1756-9737. [FDM 2016 - International Conference on Fracture and Damage Mechanics /15./. Alicante, 14.09.2016-16.09.2016] R&D Projects: GA MŠk LM2015069; GA MŠk(CZ) ED1.1.00/02.0068 Institutional support: RVO:68081723 Keywords : inclined crack * railway axle * residual fatigue lifetime * fatigue crack propagation Subject RIV: JL - Materials Fatigue, Friction Mechanics

  8. Molecular analysis of alternative transcripts of equine AXL receptor tyrosine kinase gene

    Directory of Open Access Journals (Sweden)

    Jeong-Woong Park

    2017-10-01

    Full Text Available Objective Since athletic performance is a most importance trait in horses, most research focused on physiological and physical studies of horse athletic abilities. In contrast, the molecular analysis as well as the regulatory pathway studies remain insufficient for evaluation and prediction of horse athletic abilities. In our previous study, we identified AXL receptor tyrosine kinase (AXL gene which was expressed as alternative spliced isoforms in skeletal muscle during exercise. In the present study, we validated two AXL alternative splicing transcripts (named as AXLa for long form and AXLb for short form in equine skeletal muscle to gain insight(s into the role of each alternative transcript during exercise. Methods We validated two isoforms of AXL transcripts in horse tissues by reverse transcriptase polymerase chain reaction (RT-PCR, and then cloned the transcripts to confirm the alternative locus and its sequences. Additionally, we examined the expression patterns of AXLa and AXLb transcripts in horse tissues by quantitative RT-PCR (qRT-PCR. Results Both of AXLa and AXLb transcripts were expressed in horse skeletal muscle and the expression levels were significantly increased after exercise. The sequencing analysis showed that there was an alternative splicing event at exon 11 between AXLa and AXLb transcripts. 3-dimentional (3D prediction of the alternative protein structures revealed that the structural distance of the connective region between fibronectin type 3 (FN3 and immunoglobin (Ig domain was different between two alternative isoforms. Conclusion It is assumed that the expression patterns of AXLa and AXLb transcripts would be involved in regulation of exercise-induced stress in horse muscle possibly through an NF-κB signaling pathway. Further study is necessary to uncover biological function(s and significance of the alternative splicing isoforms in race horse skeletal muscle.

  9. Molecular analysis of alternative transcripts of equine AXL receptor tyrosine kinase gene.

    Science.gov (United States)

    Park, Jeong-Woong; Song, Ki-Duk; Kim, Nam Young; Choi, Jae-Young; Hong, Seul A; Oh, Jin Hyeog; Kim, Si Won; Lee, Jeong Hyo; Park, Tae Sub; Kim, Jin-Kyoo; Kim, Jong Geun; Cho, Byung-Wook

    2017-10-01

    Since athletic performance is a most importance trait in horses, most research focused on physiological and physical studies of horse athletic abilities. In contrast, the molecular analysis as well as the regulatory pathway studies remain insufficient for evaluation and prediction of horse athletic abilities. In our previous study, we identified AXL receptor tyrosine kinase ( AXL ) gene which was expressed as alternative spliced isoforms in skeletal muscle during exercise. In the present study, we validated two AXL alternative splicing transcripts (named as AXLa for long form and AXLb for short form) in equine skeletal muscle to gain insight(s) into the role of each alternative transcript during exercise. We validated two isoforms of AXL transcripts in horse tissues by reverse transcriptase polymerase chain reaction (RT-PCR), and then cloned the transcripts to confirm the alternative locus and its sequences. Additionally, we examined the expression patterns of AXLa and AXLb transcripts in horse tissues by quantitative RT-PCR (qRT-PCR). Both of AXLa and AXLb transcripts were expressed in horse skeletal muscle and the expression levels were significantly increased after exercise. The sequencing analysis showed that there was an alternative splicing event at exon 11 between AXLa and AXLb transcripts. 3-dimentional (3D) prediction of the alternative protein structures revealed that the structural distance of the connective region between fibronectin type 3 (FN3) and immunoglobin (Ig) domain was different between two alternative isoforms. It is assumed that the expression patterns of AXLa and AXLb transcripts would be involved in regulation of exercise-induced stress in horse muscle possibly through an NF-κB signaling pathway. Further study is necessary to uncover biological function(s) and significance of the alternative splicing isoforms in race horse skeletal muscle.

  10. A Study on Lean Manufacturing Practice Carried Out for Axle Housing Plant

    Directory of Open Access Journals (Sweden)

    Rishi J. P.

    2018-01-01

    Full Text Available Lean Manufacturing is a way to deal with the elimination of waste through persistent change within the system. The assembling units in India should likewise hope to take its preferences. The Industries are energetically following the Lean assembling strategies to reduce waste and cost. The present work is the study of a manufacturing process for axle housing and to decide how Lean manufacturing process carried out for axle housing plant to improve productivity. The new shot peening machine was installed in a heat treatment plant of a housing line in an automobile rear axle assembly plant and material handling time from storage to this new machine was more and this increased lead time subsequently. To reduce this Kaizens technique was employed and a direct gravity conveyor was chosen and installed between two work stations and the part was directly fed to the new machine installed and this reduces the material handling time considerably. A cost analysis was done to realize the benefits of implementing this lean technique. Therefore reducing lead time and increasing productivity is the Prime benefits of lean manufacturing practices like lean assembly.

  11. Normalization of TAM post-receptor signaling reveals a cell invasive signature for Axl tyrosine kinase.

    Science.gov (United States)

    Kimani, Stanley G; Kumar, Sushil; Davra, Viralkumar; Chang, Yun-Juan; Kasikara, Canan; Geng, Ke; Tsou, Wen-I; Wang, Shenyan; Hoque, Mainul; Boháč, Andrej; Lewis-Antes, Anita; De Lorenzo, Mariana S; Kotenko, Sergei V; Birge, Raymond B

    2016-09-06

    Tyro3, Axl, and Mertk (TAMs) are a family of three conserved receptor tyrosine kinases that have pleiotropic roles in innate immunity and homeostasis and when overexpressed in cancer cells can drive tumorigenesis. In the present study, we engineered EGFR/TAM chimeric receptors (EGFR/Tyro3, EGFR/Axl, and EGF/Mertk) with the goals to interrogate post-receptor functions of TAMs, and query whether TAMs have unique or overlapping post-receptor activation profiles. Stable expression of EGFR/TAMs in EGFR-deficient CHO cells afforded robust EGF inducible TAM receptor phosphorylation and activation of downstream signaling. Using a series of unbiased screening approaches, that include kinome-view analysis, phosphor-arrays, RNAseq/GSEA analysis, as well as cell biological and in vivo readouts, we provide evidence that each TAM has unique post-receptor signaling platforms and identify an intrinsic role for Axl that impinges on cell motility and invasion compared to Tyro3 and Mertk. These studies demonstrate that TAM show unique post-receptor signatures that impinge on distinct gene expression profiles and tumorigenic outcomes.

  12. Effect of two heavy metals, cadmium and nickel, on the organic load removal efficiency in a laboratory UASB reactor

    International Nuclear Information System (INIS)

    Forero, Luis Eduardo; Sierra, Jorge Humberto

    2004-01-01

    Experiments were carried out in three up flow anaerobic sludge blanket, UASB, reactors each with 3 L capacity, four hours of hydraulic retention time, (HRT) and volumetric organic load of 4,8 g/L/d. After the initial start phase, which was of 4.000 hours for the three reactors, they were affected in the following way: the first reactor was continuously feed with 5 mg/L of cadmium chloride, the second one was continuously feed with 10 mg/L of nickel chloride and the last one was not affected and served as reference. Efficiency in organic load removal was measured as oxygen chemical demand (OCD), the first reactor changed from 60% in the start phase (phase one) to 18% in the cadmium-affected phase (phase two), efficiency in removal (OCI) in reactor two varied from 60 to 24% and the last one did not change in a noticeable manner. Reactor one accumulated cadmium in the mud, whereas reactor two did not do that with nickel

  13. Barley HvHMA1 is a heavy metal pump involved in mobilizing organellar Zn and Cu and plays a role in metal loading into grains

    DEFF Research Database (Denmark)

    Mikkelsen, Maria Dalgaard; Pedas, Pai; Schiller, Michaela

    2012-01-01

    Heavy metal transporters belonging to the P1B-ATPase subfamily of P-type ATPases are key players in cellular heavy metal homeostasis. Heavy metal transporters belonging to the P1B-ATPase subfamily of P-type ATPases are key players in cellular heavy metal homeostasis. In this study we investigated...

  14. Electrostimulation improves muscle perfusion but does not affect either muscle deoxygenation or pulmonary oxygen consumption kinetics during a heavy constant-load exercise.

    Science.gov (United States)

    Layec, Gwenael; Millet, Grégoire P; Jougla, Aurélie; Micallef, Jean-Paul; Bendahan, David

    2008-02-01

    Electromyostimulation (EMS) is commonly used as part of training programs. However, the exact effects at the muscle level are largely unknown and it has been recently hypothesized that the beneficial effect of EMS could be mediated by an improved muscle perfusion. In the present study, we investigated rates of changes in pulmonary oxygen consumption (VO(2p)) and muscle deoxygenation during a standardized exercise performed after an EMS warm-up session. We aimed at determining whether EMS could modify pulmonary O(2) uptake and muscle deoxygenation as a result of improved oxygen delivery. Nine subjects performed a 6-min heavy constant load cycling exercise bout preceded either by an EMS session (EMS) or under control conditions (CONT). VO(2p) and heart rate (HR) were measured while deoxy-(HHb), oxy-(HbO(2)) and total haemoglobin/myoglobin (Hb(tot)) relative contents were measured using near infrared spectroscopy. EMS significantly increased (P < 0.05) the Hb(tot) resting level illustrating a residual hyperaemia. The EMS priming exercise did not affect either the HHb time constant (17.7 +/- 14.2 s vs. 13.1 +/- 2.3 s under control conditions) or the VO(2p) kinetics (time-constant = 18.2 +/- 5.2 s vs. 15.4 +/- 4.6 s under control conditions). Likewise, the other VO(2p) parameters were unchanged. Our results further indicated that EMS warm-up improved muscle perfusion through a residual hyperaemia. However, neither VO(2p) nor [HHb] kinetics were modified accordingly. These results suggest that improved O(2) delivery by residual hyperaemia induced by EMS does not accelerate the rate of aerobic metabolism during heavy exercise at least in trained subjects.

  15. Influence of real-world engine load conditions on nanoparticle emissions from a DPF and SCR equipped heavy-duty diesel engine.

    Science.gov (United States)

    Thiruvengadam, Arvind; Besch, Marc C; Carder, Daniel K; Oshinuga, Adewale; Gautam, Mridul

    2012-02-07

    The experiments aimed at investigating the effect of real-world engine load conditions on nanoparticle emissions from a Diesel Particulate Filter and Selective Catalytic Reduction after-treatment system (DPF-SCR) equipped heavy-duty diesel engine. The results showed the emission of nucleation mode particles in the size range of 6-15 nm at conditions with high exhaust temperatures. A direct result of higher exhaust temperatures (over 380 °C) contributing to higher concentration of nucleation mode nanoparticles is presented in this study. The action of an SCR catalyst with urea injection was found to increase the particle number count by over an order of magnitude in comparison to DPF out particle concentrations. Engine operations resulting in exhaust temperatures below 380 °C did not contribute to significant nucleation mode nanoparticle concentrations. The study further suggests the fact that SCR-equipped engines operating within the Not-To-Exceed (NTE) zone over a critical exhaust temperature and under favorable ambient dilution conditions could contribute to high nanoparticle concentrations to the environment. Also, some of the high temperature modes resulted in DPF out accumulation mode (between 50 and 200 nm) particle concentrations an order of magnitude greater than typical background PM concentrations. This leads to the conclusion that sustained NTE operation could trigger high temperature passive regeneration which in turn would result in lower filtration efficiencies of the DPF that further contributes to the increased solid fraction of the PM number count.

  16. Synthesis of the adaptive continuous system for the multi-axle wheeled vehicle body oscillation damping

    Science.gov (United States)

    Zhileykin, M. M.; Kotiev, G. O.; Nagatsev, M. V.

    2018-02-01

    In order to meet the growing mobility requirements for the wheeled vehicles on all types of terrain the engineers have to develop a large number of specialized control algorithms for the multi-axle wheeled vehicle (MWV) suspension improving such qualities as ride comfort, handling and stability. The authors have developed an adaptive algorithm of the dynamic damping of the MVW body oscillations. The algorithm provides high ride comfort and high mobility of the vehicle. The article discloses a method for synthesis of an adaptive dynamic continuous algorithm of the MVW body oscillation damping and provides simulation results proving high efficiency of the developed control algorithm.

  17. New drive axles for hybrid applications in low-floor city busses. The electric axle AVE 130; Neue Antriebsachse fuer Hybridapplikationen in Niederflur-Stadtbussen. Die Elektroachse AVE 130

    Energy Technology Data Exchange (ETDEWEB)

    Solka, Ulrich [ZF Passau GmbH (Germany); Mueller, Axel M. [ZF Friedrichshafen AG (Germany)

    2009-07-01

    The contribution under consideration reports on the mechanically constructional structure of the electrically driven low-floor axle AVE 130 of ZF Friedrichshafen AG (Friedrichshafen, Federal Republic of Germany). The characteristics of the electric drive are presented with the particularities of the implemented asynchronous machine and the road performances which can be developed by a city bus using this axle. Also the system characteristics of a hybrid bus with serial hybrid drive system concerning to aggregate arrangement, mass balances and the interaction of the aggregates in the drive briefly are discussed. The results of numerical simulation regarding fuel saving potential in these systems round the remarks off.

  18. Trackside acoustic diagnosis of axle box bearing based on kurtosis-optimization wavelet denoising

    Science.gov (United States)

    Peng, Chaoyong; Gao, Xiaorong; Peng, Jianping; Wang, Ai

    2018-04-01

    As one of the key components of railway vehicles, the operation condition of the axle box bearing has a significant effect on traffic safety. The acoustic diagnosis is more suitable than vibration diagnosis for trackside monitoring. The acoustic signal generated by the train axle box bearing is an amplitude modulation and frequency modulation signal with complex train running noise. Although empirical mode decomposition (EMD) and some improved time-frequency algorithms have proved to be useful in bearing vibration signal processing, it is hard to extract the bearing fault signal from serious trackside acoustic background noises by using those algorithms. Therefore, a kurtosis-optimization-based wavelet packet (KWP) denoising algorithm is proposed, as the kurtosis is the key indicator of bearing fault signal in time domain. Firstly, the geometry based Doppler correction is applied to signals of each sensor, and with the signal superposition of multiple sensors, random noises and impulse noises, which are the interference of the kurtosis indicator, are suppressed. Then, the KWP is conducted. At last, the EMD and Hilbert transform is applied to extract the fault feature. Experiment results indicate that the proposed method consisting of KWP and EMD is superior to the EMD.

  19. A randomized cross-over trial to detect differences in arm volume after low- and heavy-load resistance exercise among patients receiving adjuvant chemotherapy for breast cancer at risk for arm lymphedema

    DEFF Research Database (Denmark)

    Bloomquist, Kira; Hayes, Sandi; Adamsen, Lis

    2016-01-01

    changes after resistance exercise with heavy loads in this population. The purpose of this study is to determine acute changes in arm volume after a session of low- and heavy-load resistance exercise among women undergoing adjuvant chemotherapy for breast cancer at risk for arm lymphedema. METHODS....../DESIGN: This is a randomized cross-over trial. PARTICIPANTS: Women receiving adjuvant chemotherapy for breast cancer who have undergone axillary lymph node dissection will be recruited from rehabilitation centers in the Copenhagen area. INTERVENTION: Participants will be randomly assigned to engage in a low- (two sets of 15...... was calculated based on changes in L-Dex scores between baseline and 72-hours post exercise sessions. DISCUSSION: Findings from this study are relevant for exercise prescription guidelines, as well as recommendations regarding participating in activities of daily living for women following surgery for breast...

  20. Development of a vehicle load control strategy for Malawi for the period 2016 to 2020

    CSIR Research Space (South Africa)

    Roux, MP

    2016-07-01

    Full Text Available Strategy and development of a five-year implementation plan for significantly improving the Directorate’s current capacity to effectively manage and enforce axle load control. Specific objectives were to: a) Assist the DRTSS to undertake an extensive...

  1. Guideline for load and resistance assessment of existing european railway bridges

    OpenAIRE

    JENSEN, Jens S; CASAS, Joan R; KAROUMI, Raid; PLOS, Mario; CREMONA, Christian; MELBOURNE, Clive

    2008-01-01

    Many of the European railway bridges are getting close to the end of their service life. At the same time the railway operators demand higher axle loads for freight trains and higher speeds for passenger trains. This requires new and better approaches for assessing both the railway loads and the resistance of railway bridges. The main objective of the "Guideline for Load and Resistance Assessment of Existing European Railway Bridges", developed within EU founded project "Sustainable Bridge...

  2. NEW APPROACH FOR TECHNOLOGY OF VOLUMETRIC – SUPERFICIAL HARDENING OF GEAR DETAILS OF THE BACK AXLE OF MOBILE MACHINES

    Directory of Open Access Journals (Sweden)

    A. I. Mihluk

    2010-01-01

    Full Text Available The new approach for technology of volumetric – superficial hardening of gear details of the back axle made of steel lowered harden ability is offered. This approach consisting in formation of intense – hardened condition on all surface of a detail.

  3. Analysis of pavement structure sensitivity to passage of oversized heavy duty vehicle in terms of bearing capacity

    Science.gov (United States)

    Dawid, Rys; Piotr, Jaskula

    2018-05-01

    Oversized heavy duty vehicles occur in traffic very rarely but they reach extremely high weights, even up to 800 tonne. The detrimental impact of these vehicles on pavement structure is much higher than in case of commercial vehicles that comprise typical traffic, thus it is necessary to assess the sensitivity of pavement structure to passage of oversized vehicles. The paper presents results of sample calculations of load equivalency factor of a heavy duty oversized vehicle with usage of mechanistic-empirical approach. The effects of pavement thickness, type of distress (cracking or rutting) and pavement condition (new or old with structural damage) were considered in the paper. Analysis revealed that a single pass of an 800 tonne oversized vehicle is equivalent to pass of up to 377 standard 100 kN axles. Load equivalency factor calculated for thin structures is almost 3 times lower than for thick structures, however, the damage effect caused by one pass of an oversized vehicle is higher in the case of thin structure. Bearing capacity of a pavement structure may be qualified as sufficient for passage of an oversized heavy duty vehicle when the measured deflection, for example in an FWD test, does not exceed the maximum deflections derived from mechanistic-empirical analysis. The paper presents sample calculation of maximum deflections which allow to consider passage of an oversized vehicle as safe over different pavement structures. The paper provides road administration with a practical tool which helps to decide whether to issue a permit of passage for a given oversized vehicle.

  4. Levels of vibration transmitted to the operator of the tractor equipped with front axle suspension

    Directory of Open Access Journals (Sweden)

    Daniele Pochi

    2013-09-01

    Full Text Available In recent years the comfort and the preservation of the health of the operators became central issues in the evolution of agricultural machinery and led to the introduction of devices aimed at improving working conditions. Thereby, for instance, the presence of air conditioner, soundproof cab and driver seat suspension became normal on agricultural tractors. The vibrations are one of the most complex issues to deal with, being determined by the characteristics and interaction of elements such as tyres, axles, mainframe, cab and seat suspension. In this respect, manufacturers are trying to improve their products, even integrating these elements with new devices such as the suspension on the front axle of the tractor, aimed at reducing the level of vibrations during the transfers at high speed. One of these underwent tests at CRA-ING. Since its purpose is to reduce the level of vibration transmitted to the driver, their measurements in different points of the tractor and in different operating conditions, were compared in order to evaluate the effectiveness of the device, expressed as time of exposure. The suspension system of the front axle is designed to absorb the oscillations (especially pitching determined by irregularities in the road surface, allowing an increased control of the vehicle at high speed, as demonstrated by the test results and confirmed by the driving impressions outlined by the operator. The action of the device under these conditions results in an increase of the exposure time, important fact because of the relevance of the road transfer operations of tractors with mounted implements or trailers to tow and of the tendency to increase the speed limit for the road tractors (in Germany were brought to 50 km h–1 for several years. The action just described is less evident with increasing irregularity of the road surface and with the decrease of the travel speed. Nevertheless, in such conditions, the device appears to

  5. Vitamin K2 regression aortic calcification induced by warfarin via Gas6/Axl survival pathway in rats.

    Science.gov (United States)

    Jiang, Xiaoyu; Tao, Huiren; Qiu, Cuiting; Ma, Xiaolei; Li, Shan; Guo, Xian; Lv, Anlin; Li, Huan

    2016-09-05

    The aim of this study was to investigate the effect of vitamin K2 on aortic calcification induced by warfarin via Gas6/Axl survival pathway in rats. A calcification model was established by administering 3mg/g warfarin to rats. Rats were divided into 9 groups: control group (0W, 4W, 6W and 12W groups), 4W calcification group, 6W calcification group, 12W calcification group, 6W calcification+6W normal group and 6W calcification+6W vitamin K2 group. Alizarin red S staining measured aortic calcium depositions; alkaline phosphatase activity in serum was measured by a kit; apoptosis was evaluated by TUNEL assay; protein expression levels of Gas6, Axl, phosphorylated Akt (p-Akt), and Bcl-2 were determined by western blotting. The calcium content, calcium depositions, ALP activity and apoptosis were significantly higher in the calcification groups than control group. Gas6, Axl, p-Akt and Bcl-2 expression was lower in the calcification group than control group. 100μg/g vitamin K2 treatment decreased calcium depositions, ALP activity and apoptosis significantly, but increased Gas6, Axl, p-Akt and Bcl-2 expression. 100μg/g vitamin K2 reversed 44% calcification. Pearson correlation analysis showed a positive correlation between formation calcification and apoptosis (R(2)=0.8853, PK2 can inhibit warfarin-induced aortic calcification and apoptosis. The regression of aortic calcification by vitamin K2 involved the Gas6/Axl axis. This data may provide a theoretical basis for future clinical treatments for aortic calcification. Copyright © 2016 Elsevier B.V. All rights reserved.

  6. Analysis of the nonlinear dynamics of a 2-axle freight wagon in curves

    DEFF Research Database (Denmark)

    Di Gialleonardo, Egidio; Bruni, Stefano; True, Hans

    2014-01-01

    This paper deals with the study of the nonlinear dynamic behaviour of 2-axle freight wagons in curves, considering the case of one single wagon (neglecting inter-car coupling forces) and of multiple wagons interacting through the buffers and the couplers. A multi-body model of a single wagon...... and of a three-car assembly is introduced, paying particular attention to the nonlinear and nonsmooth modelling of the suspensions and of the inter-car coupling elements. Using this model, a numerical analysis of the steady-state solution reached after the negotiation of curve transition is presented......, it is shown that the coupling forces exchanged by the wagons significantly affect their dynamics in a curve, reducing the amplitude of vibration....

  7. Analysis, testing and verification of the behavior of composite pavements under Florida conditions using a heavy vehicle simulator

    Science.gov (United States)

    Tapia Gutierrez, Patricio Enrique

    Whitetopping (WT) is a rehabilitation method to resurface deteriorated asphalt pavements. While some of these composite pavements have performed very well carrying heavy load, other have shown poor performance with early cracking. With the objective of analyzing the applicability of WT pavements under Florida conditions, a total of nine full-scale WT test sections were constructed and tested using a Heavy Vehicle Simulator (HVS) in the APT facility at the FDOT Material Research Park. The test sections were instrumented to monitor both strain and temperature. A 3-D finite element model was developed to analyze the WT test sections. The model was calibrated and verified using measured FWD deflections and HVS load-induced strains from the test sections. The model was then used to evaluate the potential performance of these test sections under critical temperature-load condition in Florida. Six of the WT pavement test sections had a bonded concrete-asphalt interface by milling, cleaning and spraying with water the asphalt surface. This method produced excellent bonding at the interface, with shear strength of 195 to 220 psi. Three of the test sections were intended to have an unbonded concrete-asphalt interface by applying a debonding agent in the asphalt surface. However, shear strengths between 119 and 135 psi and a careful analysis of the strain and the temperature data indicated a partial bond condition. The computer model was able to satisfactorily model the behavior of the composite pavement by mainly considering material properties from standard laboratory tests and calibrating the spring elements used to model the interface. Reasonable matches between the measured and the calculated strains were achieved when a temperature-dependent AC elastic modulus was included in the analytical model. The expected numbers of repetitions of the 24-kip single axle loads at critical thermal condition were computed for the nine test sections based on maximum tensile stresses

  8. Traffic volume and load data measurement using a portable weigh in motion system: A case study

    Directory of Open Access Journals (Sweden)

    Abu N.M. Faruk

    2016-05-01

    Full Text Available Traditionally, traffic loading characteristics are collected for pavement design and performance prediction purposes using permanent roadside weigh-in-motion (WIM stations. However, high installation and maintenance costs associated with these permanent WIM stations dictate that their deployment be mostly limited to major highways, such as the interstate network. Quite often however, pavement damage on high volume rural highways with heavy truck proportions is more severe than anticipated, and there is no effective way of quantifying the traffic loading on these highways. Therefore, this study was conducted to evaluate the potential application of portable WIM systems as a means for bringing the WIM technology to these high volume rural highways. A portable WIM unit was deployed in the Texas overweight corridor in Hidalgo County (Pharr District near the USA-Mexico border on highway FM 1016 for collecting traffic data for a minimum of three weeks in each direction. The collected traffic data were analyzed to generate traffic parameters such as volume, load spectra, and overloading information both in terms of the gross vehicle weight (GVW and axle weight. The computed traffic parameters were successful in partially explaining some of the existing pavement conditions on this highway. Overall, the study findings indicated that the portable WIM unit can be used as a convenient and cost-effective means for collecting reliable traffic information for design, analysis, and monitoring purposes. However, proper in-situ calibration of the portable WIM unit at each site is imperative prior to any real-time traffic data collection. Keywords: Traffic data, Load spectra, Truck overweight, Weigh-in-motion (WIM, Portable WIM, Texas overweight corridor

  9. Incorporating moving dynamic tyre loads in pavement design and analysis

    CSIR Research Space (South Africa)

    Steyn, WJvdM

    2000-07-01

    Full Text Available at the University of Pretoria. 4 REAL LIFE TYRE LOADS Characterisation Pavement loading has been shown by various authors to be a dynamic (time-dependent) phenomenon (Divine, 1997; Cebon, 1999). A pavement experiences a vehicle as a moving, time-varying set... frequencies. Body bounce generally dominates the dynamic loading, and is mainly caused by the response of the sprung mass of the vehicle to the pavement roughness. Axle hop becomes more significant at higher vehicle speeds and higher pavement roughnesses...

  10. Optimization of Lightweight Axles for an Innovative Carving Skateboard Based on Carbon Fiber Placement

    Directory of Open Access Journals (Sweden)

    Marc Fleischmann

    2018-02-01

    Full Text Available In 2003, the BMW Group developed a longboard called “StreetCarver”. The idea behind this product was to bring the perfect carving feeling of surf- and snowboarding on the streets by increasing the maneuverability of classical skateboard trucks. The outcome was a chassis based on complex kinematics. The negative side effect was the StreetCarver’s exceptional high weight of almost 8 kg. The main reason for this heaviness was the choice of traditional metallic engineering materials. In this research, modern fiber reinforced composites were used to lower the chassis’ mass by up to 50% to reach the weight of a common longboard. To accomplish that goal, carbon fibers were placed along pre-simulated load paths of the structural components in a so-called Tailored- Fiber-Placement process. This technology allows an angle-independent single-roving placement and leads not only to the reduction of weight but also helps to save valuable fiber material by avoiding cutting waste.

  11. 重油在含有TiO2微粒的膨化石墨上的吸附和分解%SORPTION AND DECOMPOSITION OF HEAVY OIL ON EXFOLIATED GRAPHITE LOADED WITH TiO2

    Institute of Scientific and Technical Information of China (English)

    M.Toyoda; M.Inagaki; 等

    2002-01-01

    Preparation of exfoliated graphite loaded with photoactive anatase-type TiO2 powders was successfully carried out by heating a mixture of graphite flakes and titanium isopropoxide. Fine TiO2 particles with a spherical morphology were preferentially located at the edges of graphite layers. Exfoliated graphite loaded with photoactive anatase powders showed the ability to adsorb and decompose heavy oil. Under UV irradiation, heavy oil sorbed into exfoliated graphite loaded TiO2 could be decomposed at a much faster rate than the case when TiO2 particles with the anatase structure were mixed with heavy oil.%将由天然鳞片石墨合成的层间化合物和异丙醇钛盐一起加热,成功地制得了具有光催化特性的锐钛矿粉TiO2分散在膨化石墨间的复合材料.一些具有球形结构的TiO2微粒,优先分散于石墨层的边沿.对重油而言,这种材料呈现了它在紫外(UV)光辐照下的吸附和分解作用.吸附在分散有TiO2的膨化石墨上的重油能在UV辐照下分解掉,其分解速度远比重油中混合锐钛矿结构的TiO2粒子的场合快速得多.

  12. Heat-affected zone microstructure and mechanical properties evolution for laser remanufacturing 35CrMoA axle steel

    Science.gov (United States)

    Feng, Xiangyi; Dong, Shiyun; Yan, Shixing; Liu, Xiaoting; Xu, Binshi; Pan, Fusheng

    2018-03-01

    In this article, by using orthogonal test the technological test was conducted and the optimum processing of the remanufacturing35CrMoA axle were obtained. The evolution of microstructure and mechanical property of HAZ were investigated. The microstructure of HAZ was characterized by means of OM and SEM. Meanwhile hardness distribution in HAZ and tensile property of cladding-HAZ-substrate samples were measured. The microstructure of cladding and HAZ were observed. The microsturcture evoltion and the mechanism of harden in the HAZ was discussed and revealed. The results indicated that the remanufacturing part has excellent strength due to grain refining and dispersive distribution of nanoscale cementite. The remanufacturing part will have uniform microstructure and hardness matching with that of 35CrMoA axle by using stress-relieving annealing at 580°.

  13. The integration of electrical axle drives in hybrid vehicle and electric vehicles; Die Integration elektrischer Achsantriebe in Hybrid- und Elektrofahrzeuge

    Energy Technology Data Exchange (ETDEWEB)

    Schaefer, Heinz [hofer eds GmbH, Wuerzburg (Germany)

    2009-07-01

    In the following contribution the advantages of a high integrated electrical axle module will be explained. Furthermore different electrical machines will be introduced and the specific operational behavior will be described. After a short introduction regarding the utilization of electrical machines some proposals regarding the gear ratio will be given. At the end a novel hybrid transmission with electrical power split will be introduced. (orig.)

  14. Prediction of microstructure and ductile damage of a high-speed railway axle steel during cross wedge rolling

    OpenAIRE

    Huo, Y; Lin, J; Bai, Q; Wang, B; Tang, X; Ji, H

    2016-01-01

    Microstructure and ductile damage have a significant influence on the deformation behavior of high-speed railway axles during hot cross wedge rolling (CWR) and its final performance. In this study, based on the continuum damage mechanics, a multiaxial constitutive model coupling microstructure and ductile damage was established to predict the evolution of microstructure and ductile damage of 25CrMo4 during hot CWR processes. Material constants within the multiaxial constitutive model were det...

  15. Heavy leptons

    International Nuclear Information System (INIS)

    Smith, C.H.L.

    1977-01-01

    The possibility that a new lepton may exist is discussed under the headings; theoretical reasons for the introduction of heavy leptons, classification of heavy leptons (ortho and paraleptons), discrimination between different types of lepton, decays of charged heavy leptons, production of charged heavy leptons (in e + e - storage rings, neutrino production, photoproduction, and hadroproduction), neutral heavy leptons, and hadroleptons. (U.K.)

  16. Road transport management system: a self regulation initiative to promote load optimisation, vehicle maintenance and driver wellness in heavy vehicle transport in South Africa

    CSIR Research Space (South Africa)

    Nordengen, Paul A

    2008-04-01

    Full Text Available with inadequate vehicle maintenance, driver fatigue and poor driver health, contributes significantly to South Africa’s poor road safety record. This paper describes the most recent developments of an initiative to introduce meaningful self-regulation in the heavy...

  17. Repeated Load Permanent Deformation Behavior of Mixes With and Wihtout Modified Bituments

    Directory of Open Access Journals (Sweden)

    Imran Hafeez

    2011-01-01

    Full Text Available Premature rutting in flexible pavement structure is being observed on most of the road network of Pakistan. It initiates primarily due to uncontrolled axle loading and high ambient temperatures. NHA (National Highway Authority, Pakistan has continuously been modifying aggregate gradations and penetration grade of bitumen, without any prior investigation of the mix behaviour under the prevailing axle load and environmental conditions of the country. A comprehensive laboratory investigation was carried out on six mixes ranging from finer to coarser. Specimens were subjected to cyclic loading on UTM-5P (Universal Testing Machine to study the resistance against permanent deformation of the mixes at 25, 40 and 550C. At low temperatures and stress levels, both coarse and fine graded mixes showed less accumulated strain, whereas at higher temperatures and stress levels, coarse graded mix with PMB (Polymer Modified Bitumen showed good resistance to permanent deformation.

  18. Acceleration Slip Regulation Strategy for Distributed Drive Electric Vehicles with Independent Front Axle Drive Motors

    Directory of Open Access Journals (Sweden)

    Lingfei Wu

    2015-05-01

    Full Text Available This paper presents an acceleration slip regulation strategy for distributed drive electric vehicles with two motors on the front axle. The tasks of the strategy include controlling the slip ratio to make full use of the road grip and controlling the yaw rate to eliminate the lateral movement due to the difference between motor torques. The rate of the slip ratio change can be controlled by controlling the motor torque, so that the slip ratio can be controlled by applying a proportional-integral control strategy to control the rate of the slip ratio change. The yaw rate can be controlled to almost zero by applying torque compensation based on yaw rate feedback. A coordination control strategy for the slip ratio control and yaw rate control is proposed based on analysis of the priorities and features of the two control processes. Simulations were carried out using MATLAB/Simulink, and experiments were performed on a hardware-in-loop test bench with actual motors. The results of the simulations and experiments showed that the proposed strategy could improve the longitudinal driving performance and straight line driving stability of the vehicle.

  19. Research on Optimized Torque-Distribution Control Method for Front/Rear Axle Electric Wheel Loader

    Directory of Open Access Journals (Sweden)

    Zhiyu Yang

    2017-01-01

    Full Text Available Optimized torque-distribution control method (OTCM is a critical technology for front/rear axle electric wheel loader (FREWL to improve the operation performance and energy efficiency. In the paper, a longitudinal dynamics model of FREWL is created. Based on the model, the objective functions are that the weighted sum of variance and mean of tire workload is minimal and the total motor efficiency is maximal. Four nonlinear constraint optimization algorithms, quasi-newton Lagrangian multiplier method, sequential quadratic programming, adaptive genetic algorithms, and particle swarm optimization with random weighting and natural selection, which have fast convergent rate and quick calculating speed, are used as solving solutions for objective function. The simulation results show that compared to no-control FREWL, controlled FREWL utilizes the adhesion ability better and slips less. It is obvious that controlled FREWL gains better operation performance and higher energy efficiency. The energy efficiency of FREWL in equipment transferring condition is increased by 13–29%. In addition, this paper discussed the applicability of OTCM and analyzed the reason for different simulation results of four algorithms.

  20. The Design and Performance Evaluation of Hydroformed Tubular Torsion Beam Axle

    Science.gov (United States)

    Kim, Jaehyun; Oh, Jinho; Choi, Hanho

    2010-06-01

    Suspensions for vehicles are structural devices used for suspending a vehicle body and absorbing shocks from the road. Thus, the suspensions must be designed such that they can attenuate shocks from a road and make passengers feel comfortable despite the shocks, and improve steering stability, determined by the ground contact force of tires during running of vehicles. Another important factor to be considered while designing suspensions is that the suspensions must maintain desired stiffness and desired durability despite the repeated application of shocks from roads thereto. The present relates, in general, to a tubular torsion beam for rear suspensions of vehicles and a manufacturing method thereof and, more particularly, to the provision of tubular torsion beams having excellent roll stiffness and excellent roll strength, produced through hydroforming. The hydroforming technology has a lot of benefit which is shape accuracy, good durability caused by compressive pressure, and good forming quality. In this study, the performance evaluation of the hydroformed tubular torsion beam axle is evaluated.

  1. Overcoming drug-tolerant cancer cell subpopulations showing AXL activation and epithelial–mesenchymal transition is critical in conquering ALK-positive lung cancer

    Science.gov (United States)

    Nakamichi, Shinji; Seike, Masahiro; Miyanaga, Akihiko; Chiba, Mika; Zou, Fenfei; Takahashi, Akiko; Ishikawa, Arimi; Kunugi, Shinobu; Noro, Rintaro; Kubota, Kaoru; Gemma, Akihiko

    2018-01-01

    Anaplastic lymphoma kinase tyrosine kinase inhibitors (ALK-TKIs) induce a dramatic response in non–small cell lung cancer (NSCLC) patients with the ALK fusion gene. However, acquired resistance to ALK-TKIs remains an inevitable problem. In this study, we aimed to discover novel therapeutic targets to conquer ALK-positive lung cancer. We established three types of ALK-TKI (crizotinib, alectinib and ceritinib)-resistant H2228 NSCLC cell lines by high exposure and stepwise methods. We found these cells showed a loss of ALK signaling, overexpressed AXL with epithelial-mesenchymal transition (EMT), and had cancer stem cell-like (CSC) properties, suggesting drug-tolerant cancer cell subpopulations. Similarly, we demonstrated that TGF-β1 treated H2228 cells also showed AXL overexpression with EMT features and ALK-TKI resistance. The AXL inhibitor, R428, or HSP90 inhibitor, ganetespib, were effective in reversing ALK-TKI resistance and EMT changes in both ALK-TKI-resistant and TGF-β1-exposed H2228 cells. Tumor volumes of xenograft mice implanted with established H2228-ceritinib-resistant (H2228-CER) cells were significantly reduced after treatment with ganetespib, or ganetespib in combination with ceritinib. Some ALK-positive NSCLC patients with AXL overexpression showed a poorer response to crizotinib therapy than patients with a low expression of AXL. ALK signaling-independent AXL overexpressed in drug-tolerant cancer cell subpopulations with EMT and CSC features may be commonly involved commonly involved in intrinsic and acquired resistance to ALK-TKIs. This suggests AXL and HSP90 inhibitors may be promising therapeutic drugs to overcome drug-tolerant cancer cell subpopulations in ALK-positive NSCLC patients for the reason that ALK-positive NSCLC cells do not live through ALK-TKI therapy. PMID:29930762

  2. Heavy Lift Helicopter - Cargo Handling ATC Program. Volume I. Detail Design Structural and Weights Analysis, and Static and Dynamic Load Analysis

    Science.gov (United States)

    1976-01-01

    a load cell for axial load sensing. The cylindrical spring fluid housing has a self-aligning bearing installed to suit the hoist rtounting provisions...PA dJ A L4 * f5 W 7 1 ~~t~ j"H2 j "xioA"AUSCCRCO El4 "sV. 10% PLA VIE - C : NJrAUk ATK ON AA U - . j4 5’ c IIf -O a ¶ .. ~~r~eF ON *A *~ A*WMA &fi

  3. Kinome-wide shRNA Screen Identifies the Receptor Tyrosine Kinase AXL as a Key Regulator for Mesenchymal Glioblastoma Stem-like Cells

    Directory of Open Access Journals (Sweden)

    Peng Cheng

    2015-05-01

    Full Text Available Glioblastoma is a highly lethal cancer for which novel therapeutics are urgently needed. Two distinct subtypes of glioblastoma stem-like cells (GSCs were recently identified: mesenchymal (MES and proneural (PN. To identify mechanisms to target the more aggressive MES GSCs, we combined transcriptomic expression analysis and kinome-wide short hairpin RNA screening of MES and PN GSCs. In comparison to PN GSCs, we found significant upregulation and phosphorylation of the receptor tyrosine kinase AXL in MES GSCs. Knockdown of AXL significantly decreased MES GSC self-renewal capacity in vitro and inhibited the growth of glioblastoma patient-derived xenografts. Moreover, inhibition of AXL with shRNA or pharmacologic inhibitors also increased cell death significantly more in MES GSCs. Clinically, AXL expression was elevated in the MES GBM subtype and significantly correlated with poor prognosis in multiple cancers. In conclusion, we identified AXL as a potential molecular target for novel approaches to treat glioblastoma and other solid cancers.

  4. Proseek single-plex protein assay kit system to detect sAxl and Gas6 in serological material of brain tumor patients

    Directory of Open Access Journals (Sweden)

    Heidi Jaksch-Bogensperger

    2018-06-01

    Full Text Available • The receptor tyrosine kinase (RTK Axl and its ligand Gas6 are critically involved in the pathogenesis of high-grade glioma (HGG. Both proteins were found to be overexpressed e.g. in tumor cells, mediating cell proliferation and migration as well as tumor angiogenesis and neuroinflammation. The extracellular domain of Axl (sAxl and Gas6 were found in the peri-tumoral edema and blood of animals as well as in human glioma tissue. Therefore, we monitored the level of sAxl and Gas6 in human blood samples. To increase the sensitivity of protein detection beyond commonly used standard methods we preliminary tested the innovative Proseek Single-Plex Protein Assay Kit System from Olink Bioscience together with new antibodies against the soluble RTK sAxl and its ligand Gas6. We conclude that the Proseek method is a highly sensitive and fast procedure that can be used as a possible powerful tool compared to routinely used ELISA-methods.

  5. Differential expression of the ufo/axl oncogene in human leukemia-lymphoma cell lines.

    Science.gov (United States)

    Challier, C; Uphoff, C C; Janssen, J W; Drexler, H G

    1996-05-01

    The ufo protein (also termed axl) is a member of a new family of receptor tyrosine kinases and is encoded by a transforming gene that was initially isolated from primary human myeloid leukemia cells by DNA-mediated transformation of NIH/3T3 cells. The ligand, Gas6, a protein S-related molecule lacking any known function yet, has recently been identified. We report the expression pattern of ufo mRNA in a panel of 76 human continuous leukemia-lymphoma cell lines. The gene was not expressed in cell lines derived from lymphoid malignancies (n=28), but transcription was seen in 3/11 myeloid, 0/6 monocytic, 9/13 erythroid and 11/18 megakaryocytic cell lines. Several cell lines were treated with phorbol ester leading to significant upregulation of the ufo message in constitutively positive cells. An apparent ufo mRNA overexpression was not found in any of the positive leukemia cell lines, but was identified in the drug-resistant subclones of the cervix carcinoma cell line HeLa. Southern blot analysis of restriction enzyme-digested genomic DNA did not provide evidence for gene amplification, but the HeLa subclones showed banding patterns suggestive of gene rearrangement. Two main ufo mRNA bands of 3.2 and 5.0 kb were identified; no differences in the half-lives (t1/2 = 2.5 h) of these two mRNA species could be identified. In summary, ufo, representing a novel type of receptor tyrosine kinase, is expressed solely in myeloid and erythro-megakaryocytic leukemias but not in lymphoid malignancies. These and previous data suggest an involvement of the ufo receptor tyrosine kinase in normal and malignant myelopoiesis; however, its exact role, if any, and mode of operation in leukemogenesis remains to be determined.

  6. Manual for calculating critical loads of heavy metals for soils and surface waters; preliminary guidelines for environmental quality criteria, calculation methods and input data

    NARCIS (Netherlands)

    Vries, de W.; Bakker, D.J.

    1996-01-01

    Methodologies are described for calculating critical loads of lead, cadmium, copper, zinc, nickel, chromium and mercury for soils and surface waters. The aspects which are discussed are: selection of a computation model, determination of environmental-quality criteria for the metals, collection of

  7. Effects of biodiesel, engine load and diesel particulate filter on nonvolatile particle number size distributions in heavy-duty diesel engine exhaust

    International Nuclear Information System (INIS)

    Young, Li-Hao; Liou, Yi-Jyun; Cheng, Man-Ting; Lu, Jau-Huai; Yang, Hsi-Hsien; Tsai, Ying I.; Wang, Lin-Chi; Chen, Chung-Bang; Lai, Jim-Shoung

    2012-01-01

    Highlights: ► The effects of waste cooking oil biodiesel, engine load and DOC + DPF on nonvolatile particle size distributions in HDDE exhaust. ► Increasing biodiesel blends cause slight decreases in the total particle number concentrations and negligible changes in size distributions. ► Increasing load results in modest increases in both the total particle number concentrations and sizes. ► The effects of semivolatile materials are strongest at idle, during which nonvolatile cores TOT ) decrease slightly, while the mode diameters show negligible changes with increasing biodiesel blends. For a given biodiesel blend, both the N TOT and mode diameters increase modestly with increasing load of above 25%. The N TOT at idle are highest and their size distributions are strongly affected by condensation and possible nucleation of semivolatile materials. Nonvolatile cores of diameters less than 16 nm are only observed at idle mode. The DOC + DPF shows remarkable filtration efficiency for both the core and soot particles, irrespective of the biodiesel blend and engine load under study. The N TOT post the DOC + DPF are comparable to typical ambient levels of ∼10 4 cm −3 . This implies that, without concurrent reductions of semivolatile materials, the formation of semivolatile nucleation mode particles post the aftertreatment is highly favored.

  8. Novel toggle-rate based energy-efficient scheme for heavy load real-time IM-DD OFDM-PON with ONU LLID identification in time-domain using amplitude decision.

    Science.gov (United States)

    Qin, Youxiang; Zhang, Junjie

    2017-07-10

    A novel low complexity and energy-efficient scheme by controlling the toggle-rate of ONU with time-domain amplitude identification is proposed for a heavy load downlink in an intensity-modulation and direct-detection orthogonal frequency division multiplexing passive optical network (IM-DD OFDM-PON). In a conventional OFDM-PON downlink, all ONUs have to perform demodulation for all the OFDM frames in a broadcast way no matter whether the frames are targeted to or not, which causes a huge energy waste. However, in our scheme, the optical network unit (ONU) logical link identifications (LLIDs) are inserted into each downlink OFDM frame in time-domain at the optical line terminal (OLT) side. At the ONU side, the LLID is obtained with a low complexity and high precision amplitude identification method. The ONU sets the toggle-rate of demodulation module to zero when the frames are not targeted to, which avoids unnecessary digital signal processing (DSP) energy consumption. Compared with the sleep-mode methods consisting of clock recovery and synchronization, toggle-rate shows its advantage in fast changing, which is more suitable for the heavy load scenarios. Moreover, for the first time to our knowledge, the characteristics of the proposed scheme are investigated in a real-time IM-DD OFDM system, which performs well at the received optical power as low as -21dBm. The experimental results show that 25.1% energy consumption can be saved in the receiver compared to the conventional configurations.

  9. Assessment of heavy metal pollution risks and enzyme activity of meadow soils in urban area under tourism load: a case study from Zakopane (Poland).

    Science.gov (United States)

    Ciarkowska, Krystyna

    2018-05-01

    Effect of tourism, especially skiing activities, and urbanization on chemical and biochemical properties of soils in touristy town-Zakopane-was investigated. The concentration of heavy metals, nutrients, soil organic matter (SOM), dehydrogenase (DHA), invertase (IA) and urease (Ure) activities in soils from the town centre and out of the town centre was compared with the respective values of adjacent soils in protected areas (TNP). In order to evaluate a degree of contamination and risks of degradation enrichment factor (EF), ecological risk index (RI), Nemerov Pollution Index (PI Nemerov ) as well as enzyme activity index (EAI) were calculated. Soils in the centre of Zakopane were polluted with Zn, Pb, Cd and Cu in a moderate degree when those of skiing areas were polluted with Pb and Cd in a high degree. Strong positive correlation between these metals and negative correlation between them and a distance from the main roundabout in town indicated their anthropogenic origin. Soils of both locations were also enriched in P, but depleted in SOM when compared to TNP soils. Soils of touristy areas (out of the centre) were additionally enriched in N. Activity of studied enzymes was also lowered in soils of Zakopane when compared to soils of TNP. Pollution indices, RI, PI Nemerov as well as EAI, indicated that soils of Zakopane are at risk of degradation. Soils of touristy areas are under stronger negative impact than soils of the centre because of the cumulative effect of transport of heavy metals from the city centre, pollution by skiing machinery and melting water from the artificial snow.

  10. Research on the impact of surface properties of particle on damping effect in gear transmission under high speed and heavy load

    Science.gov (United States)

    Xiao, Wangqiang; Chen, Zhiwei; Pan, Tianlong; Li, Jiani

    2018-01-01

    The vibration and noise from gear transmission have great damage on the mechanical equipment and operators. Through inelastic collisions and friction between particles, the energy can be dissipated in gear transmission. A dynamic model of particle dampers in gear transmission was put forward in this paper. The performance of particle dampers in centrifugal fields under different rotational speeds and load was investigated. The surface properties such as the impact of coefficient of restitution and friction coefficient of the particle on the damping effect were analyzed and the total energy loss was obtained by discrete element method (DEM). The vibration from time-varying mesh stiffness was effectively reduced by particle dampers and the optimum coefficient of restitution was discovered under different rotational speeds and load. Then, a test bench for gear transmission was constructed, and the vibration of driven gear and driving gear were measured through a three-directional wireless acceleration sensor. The research results agree well with the simulation results. While at relatively high speed, smaller coefficient of restitution achieves better damping effect. As to friction coefficient, at relatively high speed, the energy dissipation climbs up and then declines with the increase of the friction coefficient. The results can provide guidelines for the application of particle damper in gear transmission.

  11. Heavy Chain Diseases

    Science.gov (United States)

    ... of heavy chain produced: Alpha Gamma Mu Alpha Heavy Chain Disease Alpha heavy chain disease (IgA heavy ... the disease or lead to a remission. Gamma Heavy Chain Disease Gamma heavy chain disease (IgG heavy ...

  12. Applicability of hydraulic dynamometer for measuring load mass on forwarders

    Directory of Open Access Journals (Sweden)

    Pandur Zdravko

    2015-01-01

    Full Text Available In the last few years, with the start of wood biomass production from wood residues, the need for determining the quantity of extracted wood residuals on a landing site has appeared. The beginning of intensive usage of wood residues for wood biomass starts in lowland forest where all wood residues are extracted with forwarders. There are several ways to determine load mass on a forwarder, first and probably most accurate is the use of load cells which are installed between forwarder undercarriage and loading space. In Croatia, as far as it is known, there is no forwarder with such equipment, although manufacturers offer the installation of such equipment when buying a new forwarder. The second option is using a portable measuring platform (axle scale which was already used for research of axle loads of trucks and forwarders. The data obtained with the measuring platform are very accurate, while its deficiency is relatively great mass, large dimensions and high price. The third option is determining mass by using hydraulic dynamometer which is installed on crane between the rotator and the telescopic boom. The production and installation of such a system is very simple, and with the price it can easily compete with previously described measuring systems. The main deficiency of this system is its unsatisfying accuracy. The results of assortment mass measuring with hydraulic dynamometer installed on a hydraulic crane and discussion on factors influencing obtained results will be presented in this paper.

  13. Control allocation for for regenerative braking of electric vehicles with an electric motor at the front axle using the state-dependent Riccati equation control technique

    NARCIS (Netherlands)

    Kanarachos, S.A.; Alirezaei, M.; Jansen, S.T.H.; Maurice, J.P.

    2014-01-01

    In this paper the systematic development of an integrated braking controller for a vehicle driven by an electric motor on the front axle is presented. The objective is to engage the electric motor only during braking, up to the point at which the vehicle reaches its manoeuvrability and stability

  14. AUTOMOTIVE DIESEL MAINTENANCE 1. UNIT XIX, I--ENGINE TUNE-UP--CUMMINS DIESEL ENGINE, II--FRONT END SUSPENSION AND AXLES.

    Science.gov (United States)

    Minnesota State Dept. of Education, St. Paul. Div. of Vocational and Technical Education.

    THIS MODULE OF A 30-MODULE COURSE IS DESIGNED TO DEVELOP AN UNDERSTANDING OF DIESEL ENGINE TUNE-UP PROCEDURES AND THE DESIGN OF FRONT END SUSPENSION AND AXLES USED ON DIESEL ENGINE EQUIPMENT. TOPICS ARE (1) PRE-TUNE-UP CHECKS, (2) TIMING THE ENGINE, (3) INJECTOR PLUNGER AND VALVE ADJUSTMENTS, (4) FUEL PUMP ADJUSTMENTS ON THE ENGINE (PTR AND PTG),…

  15. Adaptive regenerative braking for electric vehicles with an electric motor at the front axle using the state dependent Riccati equation control technique

    NARCIS (Netherlands)

    Jansen, S.; Alirezaei, M.; Kanarachos, S.

    2014-01-01

    In this paper a novel adaptive regenerative braking control concept for electric vehicles with an electric motor at the front axle is presented. It is well known that the "phased" type regenerative braking systems of category B maximize the amount of regenerative energy during braking. However,

  16. Heavy baryons

    International Nuclear Information System (INIS)

    Koerner, J.G.

    1994-06-01

    We review the experimental and theoretical status of baryons containing one heavy quark. The charm and bottom baryon states are classified and their mass spectra are listed. The appropriate theoretical framework for the description of heavy baryons is the Heavy Quark Effective Theory, whose general ideas and methods are introduced and illustrated in specific examples. We present simple covariant expressions for the spin wave functions of heavy baryons including p-wave baryons. The covariant spin wave functions are used to determine the Heavy Quark Symmetry structure of flavour-changing current-induced transitions between heavy baryons as well as one-pion and one-photon transitions between heavy baryons of the same flavour. We discuss 1/m Q corrections to the current-induced transitions as well as the structure of heavy to light baryon transitions. Whenever possible we attempt to present numbers to compare with experiment by making use of further model-dependent assumptions as e.g. the constituent picture for light quarks. We highlight recent advances in the theoretical understanding of the inclusive decays of hadrons containing one heavy quark including polarization. For exclusive semileptonic decays we discuss rates, angular decay distributions and polarization effects. We provide an update of the experimental and theoretical status of lifetimes of heavy baryons and of exclusive nonleptonic two body decays of charm baryons. (orig.)

  17. Transcriptional activation of the Axl and PDGFR-α by c-Met through a ras- and Src-independent mechanism in human bladder cancer

    International Nuclear Information System (INIS)

    Yeh, Chen-Yun; Tseng, Vincent S; Lee, Yuan-Chii G; Shen, Cheng-Huang; Chow, Nan-Haw; Liu, Hsiao-Sheng; Shin, Shin-Mei; Yeh, Hsuan-Heng; Wu, Tsung-Jung; Shin, Jyh-Wei; Chang, Tsuey-Yu; Raghavaraju, Giri; Lee, Chung-Ta; Chiang, Jung-Hsien

    2011-01-01

    A cross-talk between different receptor tyrosine kinases (RTKs) plays an important role in the pathogenesis of human cancers. Both NIH-Met5 and T24-Met3 cell lines harboring an inducible human c-Met gene were established. C-Met-related RTKs were screened by RTK microarray analysis. The cross-talk of RTKs was demonstrated by Western blotting and confirmed by small interfering RNA (siRNA) silencing, followed by elucidation of the underlying mechanism. The impact of this cross-talk on biological function was demonstrated by Trans-well migration assay. Finally, the potential clinical importance was examined in a cohort of 65 cases of locally advanced and metastatic bladder cancer patients. A positive association of Axl or platelet-derived growth factor receptor-alpha (PDGFR-α) with c-Met expression was demonstrated at translational level, and confirmed by specific siRNA knock-down. The transactivation of c-Met on Axl or PDGFR-α in vitro was through a ras- and Src-independent activation of mitogen-activated protein kinase/extracellular signal-regulated kinase (MEK/ERK) pathway. In human bladder cancer, co-expression of these RTKs was associated with poor patient survival (p < 0.05), and overexpression of c-Met/Axl/PDGFR-α or c-Met alone showed the most significant correlation with poor survival (p < 0.01). In addition to c-Met, the cross-talk with Axl and/or PDGFR-α also contributes to the progression of human bladder cancer. Evaluation of Axl and PDGFR-α expression status may identify a subset of c-Met-positive bladder cancer patients who may require co-targeting therapy

  18. Heavy flavors

    International Nuclear Information System (INIS)

    Cox, B.; Gilman, F.J.; Gottschalk, T.D.

    1986-11-01

    A range of issues pertaining to heavy flavors at the SSC is examined including heavy flavor production by gluon-gluon fusion and by shower evolution of gluon jets, flavor tagging, reconstruction of Higgs and W bosons, and the study of rare decays and CP violation in the B meson system. A specific detector for doing heavy flavor physics and tuned to this latter study at the SSC, the TASTER, is described. 36 refs., 10 figs

  19. Determinación de cargas dinámicas de camiones pesados que transitan en un puente basado en algoritmos genéticos e instrumentación Genetic algorithms and instrumentation determination of dynamic loads of heavy trucks over a bridge

    Directory of Open Access Journals (Sweden)

    Edgar Muñoz

    2011-12-01

    Full Text Available Esta investigación determina las cargas por eje de los camiones que circulan por un puente ubicado en una de las vías principales de Colombia, utilizando la técnica de control BWIM (Bridge Weight in Motion, no empleada antes en el País. Nuestro grupo de investigación implementó la Metodología de los Algoritmos genéticos, instrumentación y monitoreo, para el Puente denominado Boquerón en la vía Bogotá - Villavicencio, Colombia. Para ese fin, se instrumentaron cuatro vigas con un sistema electrónico de medición de tráfico en cada carril, además de un sistema de adquisición de datos y ensayos de laboratorio. Desarrollamos la calibración de su modelo estructural y la generación de funciones matemáticas para hacer converger líneas de influencias de cargas con pruebas experimentales y así determinar las cargas en movimiento de los camiones. En adición, se desarrolló una herramienta computacional, capaz de representar con aceptable precisión las cargas en movimiento.This research determines the axle loads of trucks traveling on a bridge located in one of the most important corridors of Colombia, using the technique of control BWIM (Bridge Weight in Motion, not used before in the country. Our research group developed a Genetic Algorithm based in a trial test, implementation and monitoring to the bridge called Boquerón of Colombian Highways (Bogota - Villavicencio. For such an effort, four girders were monitored by data acquisition electronics joined by an electronic traffic log device by lane accompanied of laboratory testing for materials. Model calibration was performed by mathematical approach of in-situ influence lines compared to those obtained by modeling, giving as outcome loads of moving trucks over the bridge. In addition, we developed a computational tool, able to represent with reasonable accuracy the moving loads.

  20. An integrated control strategy for the composite braking system of an electric vehicle with independently driven axles

    Science.gov (United States)

    Sun, Fengchun; Liu, Wei; He, Hongwen; Guo, Hongqiang

    2016-08-01

    For an electric vehicle with independently driven axles, an integrated braking control strategy was proposed to coordinate the regenerative braking and the hydraulic braking. The integrated strategy includes three modes, namely the hybrid composite mode, the parallel composite mode and the pure hydraulic mode. For the hybrid composite mode and the parallel composite mode, the coefficients of distributing the braking force between the hydraulic braking and the two motors' regenerative braking were optimised offline, and the response surfaces related to the driving state parameters were established. Meanwhile, the six-sigma method was applied to deal with the uncertainty problems for reliability. Additionally, the pure hydraulic mode is activated to ensure the braking safety and stability when the predictive failure of the response surfaces occurs. Experimental results under given braking conditions showed that the braking requirements could be well met with high braking stability and energy regeneration rate, and the reliability of the braking strategy was guaranteed on general braking conditions.

  1. Shifting Control Algorithm for a Single-Axle Parallel Plug-In Hybrid Electric Bus Equipped with EMT

    Directory of Open Access Journals (Sweden)

    Yunyun Yang

    2014-01-01

    Full Text Available Combining the characteristics of motor with fast response speed, an electric-drive automated mechanical transmission (EMT is proposed as a novel type of transmission in this paper. Replacing the friction synchronization shifting of automated manual transmission (AMT in HEVs, the EMT can achieve active synchronization of speed shifting. The dynamic model of a single-axle parallel PHEV equipped with the EMT is built up, and the dynamic properties of the gearshift process are also described. In addition, the control algorithm is developed to improve the shifting quality of the PHEV equipped with the EMT in all its evaluation indexes. The key techniques of changing the driving force gradient in preshifting and shifting compensation phases as well as of predicting the meshing speed in the gear meshing phase are also proposed. Results of simulation, bench test, and real road test demonstrate that the proposed control algorithm can reduce the gearshift jerk and the power interruption time noticeably.

  2. Heavy resistance training and lymphedema

    DEFF Research Database (Denmark)

    Bloomquist, Kira; Karlsmark, Tonny; Christensen, Karl Bang

    2014-01-01

    BACKGROUND: There is limited knowledge regarding progressive resistance training during adjuvant chemotherapy and the risk of developing breast cancer-related lymphedema (BCRL). Furthermore, no studies have investigated the safety of resistance training with heavy loads (> 80% 1 repetition maximum......) in this population. 'Body and Cancer' is a six-week, nine-hour weekly, supervised, multimodal exercise intervention utilizing progressive resistance training with heavy loads for cancer patients undergoing chemotherapy. The purpose of the present study was to estimate the prevalence of BCRL in former participants......, and identify associations between progressive resistance training with heavy loads, and the development of BCRL. MATERIAL AND METHODS: This was a descriptive study. POPULATION: Women treated for breast cancer (n = 149), who had participated in the 'Body and Cancer' exercise intervention between 1 January 2010...

  3. Bridge Approach Remedies Implemented at Western Mega Site

    Science.gov (United States)

    2017-09-01

    As part of the heavy axle load (HAL) revenue service mega site testing program, the Transportation Technology Center, Inc. (TTCI) has worked closely with the Union Pacific Railroad (UP) to address bridge approach problems under HAL operations. The te...

  4. Control of rolling contact fatigue on premium rails in revenue service.

    Science.gov (United States)

    2014-11-01

    Effective rail maintenance strategies are : essential for controlling rolling contact fatigue : (RCF) and reducing wear of rails under heavy : axle load (HAL) operations. In an effort to : optimize rail maintenance strategies in revenue : service, Tr...

  5. The radial hardness-profile and the microstructure of railroad car axle materials treated by surface rolling, determined by novel examination methods

    International Nuclear Information System (INIS)

    Berecz, Tibor; Balogh, Levente; Mészáros, István; Steinbach, Ágoston

    2014-01-01

    Surface rolling is a cold-working technique used for hardening the surface of steel and ductile cast iron components. This process increases the surface hardness and improves the fatigue properties of components, so it is commonly used to treat railroad car wheel axles. The present paper examines the influence of this surface strengthening technique on the microstructure of the railroad car wheel axle material by hardness tests, optical microscopy (OM), and other novel examination methods, such as scanning electron microscopy (SEM), X-ray line profile analysis (XLPA), non-destructive magnetic evaluation (NDE) and automated electron backscatter diffraction (EBSD). The results show that surface rolling causes an increase in hardness down to a depth of ∼10 mm. It is also shown, that the increase in hardness is not due to grain refinement or change in grain morphology; thus it is likely to be caused by an increase in dislocation density

  6. The radial hardness-profile and the microstructure of railroad car axle materials treated by surface rolling, determined by novel examination methods

    Energy Technology Data Exchange (ETDEWEB)

    Berecz, Tibor, E-mail: berecz@eik.bme.hu [Department of Materials Science and Engineering, Budapest University of Technology and Economics, 1111 Budapest, Bertalan Lajos utca 7 (Hungary); Balogh, Levente, E-mail: levente@metal.elte.hu [Department of Materials Physics, Eötvös Loránd University, 1117 Budapest, Pázmány Péter sétány 1/a (Hungary); Mészáros, István, E-mail: meszaros@eik.bme.hu [Department of Materials Science and Engineering, Budapest University of Technology and Economics, 1111 Budapest, Bertalan Lajos utca 7 (Hungary); Steinbach, Ágoston, E-mail: sa984@hszk.bme.hu [Department of Materials Science and Engineering, Budapest University of Technology and Economics, 1111 Budapest, Bertalan Lajos utca 7 (Hungary)

    2014-01-13

    Surface rolling is a cold-working technique used for hardening the surface of steel and ductile cast iron components. This process increases the surface hardness and improves the fatigue properties of components, so it is commonly used to treat railroad car wheel axles. The present paper examines the influence of this surface strengthening technique on the microstructure of the railroad car wheel axle material by hardness tests, optical microscopy (OM), and other novel examination methods, such as scanning electron microscopy (SEM), X-ray line profile analysis (XLPA), non-destructive magnetic evaluation (NDE) and automated electron backscatter diffraction (EBSD). The results show that surface rolling causes an increase in hardness down to a depth of ∼10 mm. It is also shown, that the increase in hardness is not due to grain refinement or change in grain morphology; thus it is likely to be caused by an increase in dislocation density.

  7. A receptor tyrosine kinase, UFO/Axl, and other genes isolated by a modified differential display PCR are overexpressed in metastatic prostatic carcinoma cell line DU145.

    Science.gov (United States)

    Jacob, A N; Kalapurakal, J; Davidson, W R; Kandpal, G; Dunson, N; Prashar, Y; Kandpal, R P

    1999-01-01

    We have used a modified differential display PCR protocol for isolating 3' restriction fragments of cDNAs specifically expressed or overexpressed in metastatic prostate carcinoma cell line DU145. Several cDNA fragments were identified that matched to milk fat globule protein, UFO/Axl, a receptor tyrosine kinase, human homologue of a Xenopus maternal transcript, laminin and laminin receptor, human carcinoma-associated antigen, and some expressed sequence tags. The transcript for milk fat globule protein, a marker protein shown to be overexpressed in breast tumors, was elevated in DU145 cells. The expression of UFO/Axl, a receptor tyrosine kinase, was considerably higher in DU145 cells as compared to normal prostate cells and prostatic carcinoma cell line PC-3. The overexpression of UFO oncogene in DU145 cells is discussed in the context of prostate cancer metastasis.

  8. Travelling cranes for heavy reactor component handling

    International Nuclear Information System (INIS)

    Champeil, M.

    1977-01-01

    Structure and operating machinery of two travelling cranes (600 t and 450 t) used in the Framatome factory for handling heavy reactor components are described. When coupled, these cranes can lift loads up to 1000 t [fr

  9. Transcriptional activation of the Axl and PDGFR-α by c-Met through a ras- and Src-independent mechanism in human bladder cancer

    Directory of Open Access Journals (Sweden)

    Tseng Vincent S

    2011-04-01

    Full Text Available Abstract Background A cross-talk between different receptor tyrosine kinases (RTKs plays an important role in the pathogenesis of human cancers. Methods Both NIH-Met5 and T24-Met3 cell lines harboring an inducible human c-Met gene were established. C-Met-related RTKs were screened by RTK microarray analysis. The cross-talk of RTKs was demonstrated by Western blotting and confirmed by small interfering RNA (siRNA silencing, followed by elucidation of the underlying mechanism. The impact of this cross-talk on biological function was demonstrated by Trans-well migration assay. Finally, the potential clinical importance was examined in a cohort of 65 cases of locally advanced and metastatic bladder cancer patients. Results A positive association of Axl or platelet-derived growth factor receptor-alpha (PDGFR-α with c-Met expression was demonstrated at translational level, and confirmed by specific siRNA knock-down. The transactivation of c-Met on Axl or PDGFR-α in vitro was through a ras- and Src-independent activation of mitogen-activated protein kinase/extracellular signal-regulated kinase (MEK/ERK pathway. In human bladder cancer, co-expression of these RTKs was associated with poor patient survival (p p Conclusions In addition to c-Met, the cross-talk with Axl and/or PDGFR-α also contributes to the progression of human bladder cancer. Evaluation of Axl and PDGFR-α expression status may identify a subset of c-Met-positive bladder cancer patients who may require co-targeting therapy.

  10. Shock Mounting for Heavy Machines

    Science.gov (United States)

    Thompson, A. R.

    1984-01-01

    Elastomeric bearings eliminate extraneous forces. Rocket thrust transmitted from motor to load cells via support that absorbs extraneous forces so they do not affect accuracy of thrust measurements. Adapter spoked cone fits over forward end of rocket motor. Shock mounting developed for rocket engines under test used as support for heavy machines, bridges, or towers.

  11. Identification of the soluble form of tyrosine kinase receptor Axl as a potential biomarker for intracranial aneurysm rupture.

    Science.gov (United States)

    Xu, Jing; Ma, Feiqiang; Yan, Wei; Qiao, Sen; Xu, Shengquan; Li, Yi; Luo, Jianhong; Zhang, Jianmin; Jin, Jinghua

    2015-03-05

    Subarachnoid hemorrhage caused by a ruptured intracranial aneurysm (RIA) is a devastating condition with significant morbidity and mortality. Despite the fact that RIAs can be prevented by microsurgical clipping or endovascular coiling, there are no reliable means of effectively predicting IA patients at risk for rupture. The purpose of our study was to discover differentially-expressed glycoproteins in IAs with or without rupture as potential biomarkers to predict rupture. Forty age/gender-matched patients with RIA, unruptured IA (UIA), healthy controls (HCs) and disease controls (DCs) (discovery cohort, n = 10 per group) were recruited and a multiplex quantitative proteomic method, iTRAQ (isobaric Tagging for Relative and Absolute protein Quantification), was used to quantify relative changes in the lectin-purified glycoproteins in CSF from RIAs and UIAs compared to HCs and DCs. Then we verified the proteomic results in an independent set of samples (validation cohort, n = 20 per group) by enzyme-linked immunosorbent assay. Finally, we evaluated the specificity and sensitivity of the candidate marker with receiver operating characteristic (ROC) curve methods. The proteomic findings identified 294 proteins, 40 of which displayed quantitative changes unique to RIA, 13 to UIA, and 20 to IA. One of these proteins, receptor tyrosine kinase Axl, was significantly increased in RIA, as confirmed in CSF from the discovery cohort as well as in CSF and plasma from the validation cohort (p IA.

  12. Vitamin K2 inhibits rat vascular smooth muscle cell calcification by restoring the Gas6/Axl/Akt anti-apoptotic pathway.

    Science.gov (United States)

    Qiu, Cuiting; Zheng, Haijun; Tao, Huiren; Yu, Wenjun; Jiang, Xiaoyu; Li, Aiqin; Jin, Hui; Lv, Anlin; Li, Huan

    2017-09-01

    Vascular calcification is associated with cardiovascular disease as a complication of hypertension, hyperlipidemia, diabetes mellitus, and chronic kidney disease. Vitamin K2 (VK2) delays vascular calcification by an unclear mechanism. Moreover, apoptosis modulates vascular smooth muscle cell (VSMC) calcification. This paper aimed to study VK2-modified VSMC calcification and survival cell signaling mediated by growth arrest-specific gene 6 (Gas6) and its tyrosine kinase receptor Axl. Primary-cultured VSMCs were dose-dependently treated with VK2 in the presence of calcification medium for 8 days, or pre-treated for 1 h with/without the Axl inhibitor R428 (2 μmol/L) or the caspase inhibitor Z-VAD-fmk (20 μmol/L) followed by treatment with VK2 (10 μmol/L) or rmGas6 (200 nmol/L) in calcification medium for 8 days. Calcium deposition was determined by the o-cresolphthalein complexone assay and Alizarin Red S staining. Apoptosis was determined by TUNEL and flow cytometry using Annexin V-FITC and propidium iodide staining. Western blotting detected the expressions of Axl, Gas6, p-Akt, Akt, and Bcl2. VK2 significantly inhibited CaCl 2 - and β-sodium glycerophosphate (β-GP)-induced VSMC calcification and apoptosis, which was dependent on restored Gas6 expression and activated downstream signaling by Axl, p-Akt, and Bcl2. Z-VAD-fmk significantly inhibited CaCl 2 - and β-GP-induced VSMC calcification and apoptosis. Augmented recombinant mouse Gas6 protein (rmGas6) expression significantly reduced VSMC calcification and apoptosis. Furthermore, the Gas6/Axl interaction was inhibited by R428, which abolished the preventive effect of VK2 on CaCl 2 - and β-GP-induced apoptosis and calcification. These results suggest that Gas6 is critical in VK2-mediated functions that attenuate CaCl 2 - and β-GP-induced VSMC calcification by blocking apoptosis.

  13. Heavy flavours

    CERN Document Server

    Buras, Andrzej J

    1998-01-01

    This volume is a collection of review articles on the most outstanding topics in heavy flavour physics. All the authors have made significant contributions to this field. The book reviews in detail the theoretical structure of heavy flavour physics and confronts the Standard Model and some of its extensions with existing experimental data.This new edition covers new trends and ideas and includes the latest experimental information. Compared to the previous edition interesting new activities are included and some of the key contributions are updated. Particular attention is paid to the discover

  14. Heavy quarks

    International Nuclear Information System (INIS)

    Khoze, V.A.

    1983-10-01

    We discuss the results accumulated during the last five years in heavy quark physics and try to draw a simple general picture of the present situation. The survey is based on a unified point of view resulting from quantum chromodynamics. (orig.)

  15. Analysis and Design of Gravity Balance Based on the Energy Method for Heavy Load Palletizing Robot%基于能量法的重载码垛机器人重力平衡分析与设计

    Institute of Scientific and Technical Information of China (English)

    郭小宝; 赵振; 陈落根; 张东海

    2015-01-01

    In the process of heavy load palletizing robot work,large swing arm drooping frequent cause the motor to overcome the gravitational potential energy work constantly which leads to the motor torque fluctuation and huge invalid work.These affect the service life of motor drive and parts costs increasing.In this article from the perspective of energy balance,of arm can drive the movement of the coupling relationship between many parts are analyzed in detail ,balance device when the stored elastic energy change in gravitational poten-tial energy of release or storage is designed so as to achieve the gravitational potential energy balance complete-ly,and implement all the energy of the motor drive is used to transfer the motion of the moving parts,avoid the gravitational potential energy of irrational consumption.Finally Lagrange equation and general expression of gravity balance optimization algorithm are obtained.%在重载码垛机器人的工作过程中,大臂的频繁上升摆动使得电机要不断克服重力势能做功,导致电机扭矩出现波动和克服重力导致驱动能量的耗散,这将影响电机和驱动器的寿命,造成零部件成本提高。从能量平衡的角度,详细分析大臂驱动的众多零部件之间的运动耦合关系,设计并分析平衡装置存储弹性势能在重力势能发生变化时的释放或存储,从而达到重力势能完全平衡,实现电机驱动的能量全部用于运动部件的动能传递,避免重力势能的无端消耗。最后采用拉格朗日方程得出重力平衡的通用表达式和优化算法。

  16. Heavy flavours: theory summary

    OpenAIRE

    Corcella, Gennaro

    2005-01-01

    I summarize the theory talks given in the Heavy Flavours Working Group. In particular, I discuss heavy-flavour parton distribution functions, threshold resummation for heavy-quark production, progress in fragmentation functions, quarkonium production, heavy-meson hadroproduction.

  17. The MET/AXL/FGFR Inhibitor S49076 Impairs Aurora B Activity and Improves the Antitumor Efficacy of Radiotherapy.

    Science.gov (United States)

    Clémenson, Céline; Chargari, Cyrus; Liu, Winchygn; Mondini, Michele; Ferté, Charles; Burbridge, Mike F; Cattan, Valérie; Jacquet-Bescond, Anne; Deutsch, Eric

    2017-10-01

    Several therapeutic agents targeting HGF/MET signaling are under clinical development as single agents or in combination, notably with anti-EGFR therapies in non-small cell lung cancer (NSCLC). However, despite increasing data supporting a link between MET, irradiation, and cancer progression, no data regarding the combination of MET-targeting agents and radiotherapy are available from the clinic. S49076 is an oral ATP-competitive inhibitor of MET, AXL, and FGFR1-3 receptors that is currently in phase I/II clinical trials in combination with gefitinib in NSCLC patients whose tumors show resistance to EGFR inhibitors. Here, we studied the impact of S49076 on MET signaling, cell proliferation, and clonogenic survival in MET-dependent (GTL16 and U87-MG) and MET-independent (H441, H460, and A549) cells. Our data show that S49076 exerts its cytotoxic activity at low doses on MET-dependent cells through MET inhibition, whereas it inhibits growth of MET-independent cells at higher but clinically relevant doses by targeting Aurora B. Furthermore, we found that S49076 improves the antitumor efficacy of radiotherapy in both MET-dependent and MET-independent cell lines in vitro and in subcutaneous and orthotopic tumor models in vivo In conclusion, our study demonstrates that S49076 has dual antitumor activity and can be used in combination with radiotherapy for the treatment of both MET-dependent and MET-independent tumors. These results support the evaluation of combined treatment of S49076 with radiation in clinical trials without patient selection based on the tumor MET dependency status. Mol Cancer Ther; 16(10); 2107-19. ©2017 AACR . ©2017 American Association for Cancer Research.

  18. Heavy weights

    International Nuclear Information System (INIS)

    2001-01-01

    The paper mentions the important thing that it was for the country, exporting the first shipping of crude de Castilla to a company of asphalts in United States. It was not a common sale, as those that it carries out the company with the crude of Cusiana or Cano Limon. The new of this shipping is that it was the first successful test of marketing the Colombian heavy crude in the exterior, since previously it was almost considered a curse to find heavy crude by the difficulties of its transport. Today it can be taken to any refinery of the world and the best test is that, after almost a year of efforts to overcome the barriers of the transport, the company achieved its conduction from the Castilla Field, in proximities to Villavicencio, until the Covenas Port, in the Caribbean Colombian coast

  19. Heavy ions

    CERN Multimedia

    CERN. Geneva; Antinori, Federico

    2001-01-01

    Colliding two heavy nuclei at ultrarelativistic energies allows to create in the laboratory a bulk system with huge density, pressure and temperature and to study its properties. It is estimated that in Pb-Pb collisions at CERN-SPS we reach over an appreciable volume an energy density which exceeds by more than a factor 20 that of normal nuclear matter. At such densities, the hadrons are so closely packed that they interpenetrate; novel physics phenomena are expected to appear. QCD predicts that under such conditions a phase transition from a system composed of colourless hadrons to a Quark-Gluon Plasma (QGP) should occur. A rich ultrarelativistic heavy-ion physics programme is under way both at BNL-AGS and at CERN-SPS since 1986. The results obtained so far have led CERN to officially announce evidence for a new state of matter last year. A long-range programme of heavy-ion physics at higher energies is under way (BNL-RHIC) and in preparation (CERN-LHC). These lectures are meant as an introduction to the phy...

  20. Heavy ions

    CERN Multimedia

    CERN. Geneva. Audiovisual Unit

    2002-01-01

    Colliding two heavy nuclei at ultrarelativistic energies allows to create in the laboratory a bulk system with huge density, pressure and temperature and to study its properties. It is estimated that in Pb-Pb collisions at CERN-SPS we reach over an appreciable volume an energy density which exceeds by more than a factor 20 that of normal nuclear matter. At such densities, the hadrons are so closely packed that they interpenetrate; novel physics phenomena are expected to appear. QCD predicts that under such conditions a phase transition from a system composed of colourless hadrons to a Quark-Gluon Plasma (QGP) should occur. A rich ultrarelativistic heavy-ion physics programme is under way both at BNL-AGS and at CERN-SPS since 1986. The results obtained so far have led CERN to officially announce evidence for a new state of matter last year. A long-range programme of heavy-ion physics at higher energies is under way (BNL-RHIC) and in preparation (CERN-LHC). These lectures are meant as an introduction to the phy...

  1. Load carriage, human performance, and employment standards.

    Science.gov (United States)

    Taylor, Nigel A S; Peoples, Gregory E; Petersen, Stewart R

    2016-06-01

    The focus of this review is on the physiological considerations necessary for developing employment standards within occupations that have a heavy reliance on load carriage. Employees within military, fire fighting, law enforcement, and search and rescue occupations regularly work with heavy loads. For example, soldiers often carry loads >50 kg, whilst structural firefighters wear 20-25 kg of protective clothing and equipment, in addition to carrying external loads. It has long been known that heavy loads modify gait, mobility, metabolic rate, and efficiency, while concurrently elevating the risk of muscle fatigue and injury. In addition, load carriage often occurs within environmentally stressful conditions, with protective ensembles adding to the thermal burden of the workplace. Indeed, physiological strain relates not just to the mass and dimensions of carried objects, but to how those loads are positioned on and around the body. Yet heavy loads must be borne by men and women of varying body size, and with the expectation that operational capability will not be impinged. This presents a recruitment conundrum. How do employers identify capable and injury-resistant individuals while simultaneously avoiding discriminatory selection practices? In this communication, the relevant metabolic, cardiopulmonary, and thermoregulatory consequences of loaded work are reviewed, along with concomitant impediments to physical endurance and mobility. Also emphasised is the importance of including occupation-specific clothing, protective equipment, and loads during work-performance testing. Finally, recommendations are presented for how to address these issues when evaluating readiness for duty.

  2. Why is it so difficult to determine the lateral Position of the Rails by a Measurement of the Motion of an Axle on a moving Vehicle?

    DEFF Research Database (Denmark)

    True, Hans; Christiansen, Lasse Engbo

    2017-01-01

    impossible to draw any conclusions. We may therefore ask: does a wheel set follow the track disturbances exactly? In this article we investigate the lateral dynamics of a half-car vehicle model with two-axle bogies running on a rigid tangent track with sinusoidal lateral disturbances of the rails...... or period or several of these together. The results are discussed, and we must conclude that it is in general impossible to determine the track geometry from the motion of a wheel set....

  3. The Asymmetry is Derived from Mechanical Interlocking of Achiral Axle and Achiral Ring Components –Syntheses and Properties of Optically Pure [2]Rotaxanes–

    Directory of Open Access Journals (Sweden)

    Keiji Hirose

    2018-01-01

    Full Text Available Rotaxanes consisting of achiral axle and achiral ring components can possess supramolecular chirality due to their unique geometrical architectures. To synthesize such chiral rotaxanes, we adapted a prerotaxane method based on aminolysis of a metacyclophane type prerotaxane that had planar chirality, which is composed of an achiral stopper unit and a crown ether type ring component. The prerotaxanes were well resolved using chiral HPLC into a pair of enantiomerically pure prerotaxanes, which were transferred into corresponding chiral rotaxanes, respectively. Obtained chiral rotaxanes were revealed to have considerable enantioselectivity.

  4. Axle-sleeve Structured MWCNTs/Polyaniline Composite Film as Cost-effective Counter-Electrodes for High Efficient Dye-Sensitized Solar Cells

    International Nuclear Information System (INIS)

    Niu, Haihong; Qin, Shengxian; Mao, Xiaoli; Zhang, Shouwei; Wang, Renbao; Wan, Lei; Xu, Jinzhang; Miao, Shiding

    2014-01-01

    Graphical abstract: Axle-sleeve structured composite materials made with carbon nanotubes and polyaniline were prepared via a co-polymerization strategy. The composite materials were employed as cost-effective counter electrode modifier in dye-sensitized solar cells which demonstrate a comparable photo-to-electron conversion efficiency as the Pt catalyst. - Highlights: • Axle-sleeve structured MWCNT/PANI composite was prepared. • The optimum mass ratio of MWCNT/ANIranges between 1:3 and 1:1. • The π-π drive force was confirmed by spectroscopicmeans. • The polymerization time of 12∼24 hrs affords the highest conversion efficiency. • The DSSCs assembled with the MWCNTs/PANI CEs exhibit a comparable η(7.21%) as that with Pt CE (7.59%). - Abstract: Axle-sleeve structured composite materials made with multi-walled carbon nanotubes (MWCNTs) and polyaniline (PANI) were prepared, characterized, and employed as cost-effective counter electrodes (CEs) in dye-sensitized solar cells (DSSCs). The composite was synthesized by co-polymerization of aniline with carboxylated MWCNTs by using ammonium persulfate in the acidic medium. Thin films of MWCNTs/PANI were prepared via a spin coating technique followed by thermal treatment in N 2 atmosphere. The micro-structure of the composite was studied by scanning electron microscopy (SEM) and transmission electron microscopy (TEM) linked with energy dispersive spectroscopy (EDS). The coating layer of PANI on the MWCNTs and new-formed chemical bonds between MWCNTs and PANI was studied by UV-Vis absorption, X-ray photoelectron spectroscopy (XPS), Raman and FT-IR spectroscopic means. The effect of the multiple-level porosity or the axle-sleeve structures in the composite of MWCNTs/PANI on the electro-catalytic activity was investigated by cyclic voltammetry (CV) and electrochemical impedance spectroscopic (EIS) analysis. The DSSCs assembled with MWCNTs/PANI as CEs exhibit a comparable energy conversion efficiency (η) of 7

  5. Optimal design of high-speed loading spindle based on ABAQUS

    Science.gov (United States)

    Yang, Xudong; Dong, Yu; Ge, Qingkuan; Yang, Hai

    2017-12-01

    The three-dimensional model of high-speed loading spindle is established by using ABAQUS’s modeling module. A finite element analysis model of high-speed loading spindle was established by using spring element to simulate bearing boundary condition. The static and dynamic performance of the spindle structure with different specifications of the rectangular spline and the different diameter neck of axle are studied in depth, and the influence of different spindle span on the static and dynamic performance of the high-speed loading spindle is studied. Finally, the optimal structure of the high-speed loading spindle is obtained. The results provide a theoretical basis for improving the overall performance of the test-bed

  6. Heavy quark effective theory and heavy baryon transitions

    International Nuclear Information System (INIS)

    Hussain, F.

    1992-01-01

    The heavy quark effective theory (HQET) is applied to study the weak decay of heavy mesons and heavy baryons and to predict the form factors for heavy to heavy and heavy to light transitions. 28 refs, 10 figs, 2 tabs

  7. Seismic re-evaluation of Heavy Water Plant, Kota

    International Nuclear Information System (INIS)

    Parulekar, Y.M.; Reddy, G.R.; Vaze, K.K.; Kushwaha, H.S.

    2003-10-01

    This report deals with seismic re-evaluation of Heavy Water Plant, Kota. Heavy Water Plant, Kota handles considerable amount of H 2 S gas, which is very toxic. During the original design stage as per IS 1893-1966 seismic coefficient for zone-I was zero. Therefore earthquake and its effects were not considered while designing the heavy water plant structures. However as per IS 1893 (1984) the seismic coefficient for zone-I is 0.01 g. Hence seismic re-evaluation of various structures of the heavy water plant is carried out. Analysis of the heavy water plant structures was carried out for self weight, equipment load and earthquake load. Pressure loading was also considered in case of H 2 S storage tanks. Soil structure interaction effect was considered in the analysis. The combined stresses in the structures due to earthquake and dead load were checked with the allowable stresses. (author)

  8. New portal axle for low-floor electric-powered city buses; Neue Portalachse fuer Niederflur-Stadtbusse mit E-Antrieb

    Energy Technology Data Exchange (ETDEWEB)

    Mueller, Axel Michael [ZF Friedrichshafen AG, Friedrichshafen (Germany); Solka, Ulrich [ZF Passau GmbH, Passau (Germany)

    2010-07-01

    Serial hybrid systems do have due to the very distinctive intra-urban driving cycles and the low average speeds in city bus applications very good technical characteristics regarding reduction of emissions and fuel consumption. Hence, in comparison to passenger car applications this technical solution has found a wide spreading in the field of city busses. This contribution describes the essential characteristics of the new-developed, electrically driven low floor portal axle AVE 130 for city buses from ZF. Beside the main features of the mechanical constructive assembly, the qualities of the electric drive with the features of the specifically developed asynchronous electrical machines are shown. Another main focus forms the description of the system characteristics of a city bus, which is equipped with a serial hybrid system and the new electrical portal axle. On this occasion, traction performances, aggregate arrangement, weight balances and the interaction of the components in the electrical driveline are discussed. Finally the results of simulation calculations regarding the fuel saving potential in such systems round the paper out. (orig.)

  9. Intracellular signaling of the Ufo/Axl receptor tyrosine kinase is mediated mainly by a multi-substrate docking-site.

    Science.gov (United States)

    Braunger, J; Schleithoff, L; Schulz, A S; Kessler, H; Lammers, R; Ullrich, A; Bartram, C R; Janssen, J W

    1997-06-05

    Ufo/Axl belongs to a new family of receptor tyrosine kinases with an extracellular structure similar to that of neural cell adhesion molecules. In order to elucidate intracellular signaling, the cytoplasmic moiety of Ufo/Axl was used to screen an expression library according to the CORT (cloning of receptor targets) method. Three putative Ufo substrates were identified: phospholipase Cgamma1 (PLCgamma), as well as p85alpha and p85beta subunits of phosphatidylinositol 3'-kinase (PI3-kinase). Subsequently, chimeric EGFR/Ufo receptors consisting of the extracellular domains of the epidermal growth factor receptor (EGFR) and the transmembrane and intracellular moiety of Ufo were engineered. Using different far-Western blot analyses and coimmunoprecipitation assays, receptor binding of PLCgamma and p85 proteins as well as GRB2, c-src and lck was examined in vitro and in vivo. Competitive inhibition of substrate binding and mutagenesis experiments with EGFR/Ufo constructs revealed C-terminal tyrosine 821 (EILpYVNMDEG) as a docking site for multiple effectors, namely PLCgamma, p85 proteins, GRB2, c-src and lck. Tyrosine 779 (DGLpYALMSRC) demonstrated an additional, but lower binding affinity for the p85 proteins in vitro. In addition, binding of PLCgamma occurred through tyrosine 866 (AGRpYVLCPST). Moreover, our in vivo data indicate that further direct or indirect binding sites for PLCgamma, GRB2, c-src and lck on the human Ufo receptor may exist.

  10. Heavy Menstrual Bleeding (Menorrhagia)

    Science.gov (United States)

    ... Us Information For… Media Policy Makers Blood Disorders Heavy Menstrual Bleeding Recommend on Facebook Tweet Share Compartir ... It can also be bleeding that is very heavy. How do you know if you have heavy ...

  11. Heavy flavour in ALICE

    CERN Document Server

    Pillot, Philippe

    2008-01-01

    Open heavy flavours and heavy quarkonium states are expected to provide essential informa- tion on the properties of the strongly interacting system fo rmed in the early stages of heavy-ion collisions at very high energy density. Such probes are espe cially promising at LHC energies where heavy quarks (both c and b) are copiously produced. The ALICE detector shall measure the production of open heavy flavours and heavy quarkonium st ates in both proton-proton and heavy-ion collisions at the LHC. The expected performances of ALICE for heavy flavour physics is discussed based on the results of simulation studies on a s election of benchmark channels

  12. ORNL-GM: Development of Ionic Liquid-Additized, GF-5/6 Compatible Low-Viscosity Oils for Automotive Engine and Rear Axle Lubrication for 4% Improved Fuel Economy

    Energy Technology Data Exchange (ETDEWEB)

    Qu, Jun [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Zhou, Yan [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Luo, Huimin [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Toops, Todd J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Brookshear, Daniel W. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Stump, Benjamin C. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Viola, Michael B. [General Motors (GM) Technical Center, Pontiac, MI (United States); Zreik, Khaled [General Motors (GM) Technical Center, Pontiac, MI (United States); Ahmed, Tasfia [General Motors (GM) Technical Center, Pontiac, MI (United States)

    2017-01-01

    The overall objective of this project are as follows: Further develop ionic liquid (IL)-additized lowviscosity engine oils meeting the GF-5/6 specifications and possessing superior lubricating characteristics; Expand the IL additive technology to rear axle lubricants; and Seek a combined improvement in the vehicle fuel economy

  13. THE LIFETIME EXTENSION OF CAR AXLES TYPES OF RU1 AND RUSH WHEELSET FREIGHT CARS, RESTORED BY THE METHOD OF PLASMA-ARC METALLIZATION OF THE NECK AND UNDER PARTS MANUAL

    Directory of Open Access Journals (Sweden)

    V. I. Zelenin

    2009-03-01

    Full Text Available The restoration method for the journals and wheel seats of the freight wagon wheelsets by means of plasma-arc metallization is presented and the results of the bench fatigue tests with the advisable operation life of the axles restored are given.

  14. Load forecasting

    International Nuclear Information System (INIS)

    Mak, H.

    1995-01-01

    Slides used in a presentation at The Power of Change Conference in Vancouver, BC in April 1995 about the changing needs for load forecasting were presented. Technological innovations and population increase were said to be the prime driving forces behind the changing needs in load forecasting. Structural changes, market place changes, electricity supply planning changes, and changes in planning objectives were other factors discussed. It was concluded that load forecasting was a form of information gathering, that provided important market intelligence

  15. Comparison of contact stresses of the test tyres used by the one third scale model mobile load simulator (MMLS3) and the full-scale test tyres of the Heavy Vehicle Simulator (HVS) - a summary

    CSIR Research Space (South Africa)

    De Beer, Morris

    2007-07-01

    Full Text Available This paper summarises the results of a study in which the maximum vertical contact stressess of the one third scale test tyres of the Model Mobile Load Simulator (MMLS3) were compared with those measured for three types of full-scale test tyres...

  16. Extended-Kalman-filter-based regenerative and friction blended braking control for electric vehicle equipped with axle motor considering damping and elastic properties of electric powertrain

    Science.gov (United States)

    Lv, Chen; Zhang, Junzhi; Li, Yutong

    2014-11-01

    Because of the damping and elastic properties of an electrified powertrain, the regenerative brake of an electric vehicle (EV) is very different from a conventional friction brake with respect to the system dynamics. The flexibility of an electric drivetrain would have a negative effect on the blended brake control performance. In this study, models of the powertrain system of an electric car equipped with an axle motor are developed. Based on these models, the transfer characteristics of the motor torque in the driveline and its effect on blended braking control performance are analysed. To further enhance a vehicle's brake performance and energy efficiency, blended braking control algorithms with compensation for the powertrain flexibility are proposed using an extended Kalman filter. These algorithms are simulated under normal deceleration braking. The results show that the brake performance and blended braking control accuracy of the vehicle are significantly enhanced by the newly proposed algorithms.

  17. Heavy metal jako subkultura

    OpenAIRE

    KOUTNÁ, Daniela

    2016-01-01

    This bachelor thesis deals with heavy metal subculture. Its aim is to introduce the most important branches and to show broadness of heavy metal. This bachelor thesis describes development and history, briefly shows Czech heavy metal history alongside with the biggest and most popular Czech heavy metal festivals. It shows the most dressing concerns of society against this style.

  18. Deuterium and heavy water

    International Nuclear Information System (INIS)

    Vasaru, G.; Ursu, D.; Mihaila, A.; Szentgyorgyi, P.

    1975-01-01

    This bibliography on deuterium and heavy water contains 3763 references (1932-1974) from 43 sources of information. An author index and a subject index are given. The latter contains a list of 136 subjects, arranged in 13 main topics: abundance of deuterium , catalysts, catalytic exchange, chemical equilibria, chemical kinetics, deuterium and heavy water analysis, deuterium and heavy water properties, deuterium and heavy water separation, exchange reactions, general review, heavy water as moderator, isotope effects, synthesis of deuterium compounds

  19. Equivalent damage of loads on pavements

    CSIR Research Space (South Africa)

    Prozzi, JA

    2009-05-26

    Full Text Available This report describes a new methodology for the determination of Equivalent Damage Factors (EDFs) of vehicles with multiple axle and wheel configurations on pavements. The basic premise of this new procedure is that "equivalent pavement response...

  20. Beam loading

    OpenAIRE

    Boussard, Daniel

    1987-01-01

    We begin by giving a description of the radio-frequency generator-cavity-beam coupled system in terms of basic quantities. Taking beam loading and cavity detuning into account, expressions for the cavity impedance as seen by the generator and as seen by the beam are derived. Subsequently methods of beam-loading compensation by cavity detuning, radio-frequency feedback and feedforward are described. Examples of digital radio-frequency phase and amplitude control for the special case of superco...

  1. Economic impact analysis of load forecasting

    International Nuclear Information System (INIS)

    Ranaweera, D.K.; Karady, G.G.; Farmer, R.G.

    1997-01-01

    Short term load forecasting is an essential function in electric power system operations and planning. Forecasts are needed for a variety of utility activities such as generation scheduling, scheduling of fuel purchases, maintenance scheduling and security analysis. Depending on power system characteristics, significant forecasting errors can lead to either excessively conservative scheduling or very marginal scheduling. Either can induce heavy economic penalties. This paper examines the economic impact of inaccurate load forecasts. Monte Carlo simulations were used to study the effect of different load forecasting accuracy. Investigations into the effect of improving the daily peak load forecasts, effect of different seasons of the year and effect of utilization factors are presented

  2. The Atlas load protection switch

    CERN Document Server

    Davis, H A; Dorr, G; Martínez, M; Gribble, R F; Nielsen, K E; Pierce, D; Parsons, W M

    1999-01-01

    Atlas is a high-energy pulsed-power facility under development to study materials properties and hydrodynamics experiments under extreme conditions. Atlas will implode heavy liner loads (m~45 gm) with a peak current of 27-32 MA delivered in 4 mu s, and is energized by 96, 240 kV Marx generators storing a total of 23 MJ. A key design requirement for Atlas is obtaining useful data for 95601130f all loads installed on the machine. Materials response calculations show current from a prefire can damage the load requiring expensive and time consuming replacement. Therefore, we have incorporated a set of fast-acting mechanical switches in the Atlas design to reduce the probability of a prefire damaging the load. These switches, referred to as the load protection switches, short the load through a very low inductance path during system charge. Once the capacitors have reached full charge, the switches open on a time scale short compared to the bank charge time, allowing current to flow to the load when the trigger pu...

  3. Beam loading

    CERN Document Server

    Gamp, Alexander

    2013-01-01

    We begin by giving a description of the radio-frequency generator-cavity-beam coupled system in terms of basic quantities. Taking beam loading and cavity detuning into account, expressions for the cavity impedance as seen by the generator and as seen by the beam are derived. Subsequently methods of beam-loading compensation by cavity detuning, radio-frequency feedback and feedforward are described. Examples of digital radio-frequency phase and amplitude control for the special case of superconducting cavities are also given. Finally, a dedicated phase loop for damping synchrotron oscillations is discussed.

  4. Beam loading

    International Nuclear Information System (INIS)

    Gamp, Alexander

    2013-01-01

    We begin by giving a description of the radio-frequency generator-cavity-beam coupled system in terms of basic quantities. Taking beam loading and cavity detuning into account, expressions for the cavity impedance as seen by the generator and as seen by the beam are derived. Subsequently methods of beam-loading compensation by cavity detuning, radio-frequency feedback and feedforward are described. Examples of digital radio-frequency phase and amplitude control for the special case of superconducting cavities are also given. Finally, a dedicated phase loop for damping synchrotron oscillations is discussed. (author)

  5. The determination of some heavy metals in food samples by flame atomic absorption spectrometry after their separation-preconcentration on bis salicyl aldehyde, 1,3 propan diimine (BSPDI) loaded on activated carbon

    International Nuclear Information System (INIS)

    Ghaedi, M.; Shokrollahi, A.; Kianfar, A.H.; Mirsadeghi, A.S.; Pourfarokhi, A.; Soylak, M.

    2008-01-01

    A sensitive and simple method for the simultaneous preconcentration of Cr 3+ , Fe 3+ , Cu 2+ , Ni 2+ , Co 2+ and Zn 2+ in real samples has been reported. The method is based on the adsorption of analytes on bis salicyl aldehyde, 1,3 propan diimine (BSPDI) loaded on activated carbon. The adsorbed metals on modified activated carbon were eluted using 8 mL of 2 mol L -1 nitric acid in acetone or 10 mL of 4 mol L -1 HNO 3 . The influences of the analytical parameters including pH and sample volume were investigated. The effects of matrix ions on the retentions of the analytes were also examined. The recoveries of analytes were generally quantitative. The method has been successfully applied for these metals content evaluation in some food samples

  6. Load sensor

    NARCIS (Netherlands)

    Van den Ende, D.; Almeida, P.M.R.; Dingemans, T.J.; Van der Zwaag, S.

    2007-01-01

    The invention relates to a load sensor comprising a polymer matrix and a piezo-ceramic material such as PZT, em not bedded in the polymer matrix, which together form a compos not ite, wherein the polymer matrix is a liquid crystalline resin, and wherein the piezo-ceramic material is a PZT powder

  7. Carbohydrate Loading.

    Science.gov (United States)

    Csernus, Marilyn

    Carbohydrate loading is a frequently used technique to improve performance by altering an athlete's diet. The objective is to increase glycogen stored in muscles for use in prolonged strenuous exercise. For two to three days, the athlete consumes a diet that is low in carbohydrates and high in fat and protein while continuing to exercise and…

  8. Multivariate-Statistical Assessment of Heavy Metals for Agricultural Soils in Northern China

    OpenAIRE

    Yang, Pingguo; Yang, Miao; Mao, Renzhao; Shao, Hongbo

    2014-01-01

    The study evaluated eight heavy metals content and soil pollution from agricultural soils in northern China. Multivariate and geostatistical analysis approaches were used to determine the anthropogenic and natural contribution of soil heavy metal concentrations. Single pollution index and integrated pollution index could be used to evaluate soil heavy metal risk. The results show that the first factor explains 27.3% of the eight soil heavy metals with strong positive loadings on Cu, Zn, and C...

  9. SU-F-T-251: The Quality Assurance for the Heavy Patient Load Department in the Developing Country: The Primary Experience of An Entire Workflow QA Process Management in Radiotherapy

    International Nuclear Information System (INIS)

    Xie, J; Wang, J; Peng, J; Chen, J; Hu, W

    2016-01-01

    Purpose: To implement an entire workflow quality assurance (QA) process in the radiotherapy department and to reduce the error rates of radiotherapy based on the entire workflow management in the developing country. Methods: The entire workflow QA process management starts from patient registration to the end of last treatment including all steps through the entire radiotherapy process. Error rate of chartcheck is used to evaluate the the entire workflow QA process. Two to three qualified senior medical physicists checked the documents before the first treatment fraction of every patient. Random check of the treatment history during treatment was also performed. A total of around 6000 patients treatment data before and after implementing the entire workflow QA process were compared from May, 2014 to December, 2015. Results: A systemic checklist was established. It mainly includes patient’s registration, treatment plan QA, information exporting to OIS(Oncology Information System), documents of treatment QAand QA of the treatment history. The error rate derived from the chart check decreases from 1.7% to 0.9% after our the entire workflow QA process. All checked errors before the first treatment fraction were corrected as soon as oncologist re-confirmed them and reinforce staff training was accordingly followed to prevent those errors. Conclusion: The entire workflow QA process improved the safety, quality of radiotherapy in our department and we consider that our QA experience can be applicable for the heavily-loaded radiotherapy departments in developing country.

  10. SU-F-T-251: The Quality Assurance for the Heavy Patient Load Department in the Developing Country: The Primary Experience of An Entire Workflow QA Process Management in Radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Xie, J; Wang, J; Peng, J; Chen, J; Hu, W [Fudan University Shanghai Cancer Center, Shanghai, Shanghai (China)

    2016-06-15

    Purpose: To implement an entire workflow quality assurance (QA) process in the radiotherapy department and to reduce the error rates of radiotherapy based on the entire workflow management in the developing country. Methods: The entire workflow QA process management starts from patient registration to the end of last treatment including all steps through the entire radiotherapy process. Error rate of chartcheck is used to evaluate the the entire workflow QA process. Two to three qualified senior medical physicists checked the documents before the first treatment fraction of every patient. Random check of the treatment history during treatment was also performed. A total of around 6000 patients treatment data before and after implementing the entire workflow QA process were compared from May, 2014 to December, 2015. Results: A systemic checklist was established. It mainly includes patient’s registration, treatment plan QA, information exporting to OIS(Oncology Information System), documents of treatment QAand QA of the treatment history. The error rate derived from the chart check decreases from 1.7% to 0.9% after our the entire workflow QA process. All checked errors before the first treatment fraction were corrected as soon as oncologist re-confirmed them and reinforce staff training was accordingly followed to prevent those errors. Conclusion: The entire workflow QA process improved the safety, quality of radiotherapy in our department and we consider that our QA experience can be applicable for the heavily-loaded radiotherapy departments in developing country.

  11. Material characteristics and tribolotical characteristics of finished boundary layers of heavy-duty ceramics under tribological load. Final report; Werkstoffmechanische und tribologische Charakterisierung bearbeiteter und tribologisch beanspruchter Randschichten von Hochleistungskeramiken. Abschlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Zeller, R.; Pfeiffer, W.; Hollstein, T.

    2000-04-01

    Test pieces of heavy-duty ceramics (SSiC, SiSiC, Si{sub 3}N{sub 4}) were worked by different finishing processes and then analyzed for their material characteristics and tested in sliding and rolling wear tests. It was found that in case of coarse treatment, the influence of strength-increasing intrinsic stresses from finishing may exceed the influence of damage caused by finishing. The same applies to the tribological characteristics of ceramic components in case of preferential mechanical wear on the boundary layer. While polished surfaces of SiC, owing to a lack of microhydrodynamic lubricating effects, have catastrophic adhesive wear in sliding wear tests, fine lapping has advantages especially in the run-in phase. Coarse-lapped surfaces have a less pronounced lubricating effect in the early stages than fine-lapped surfaces, but the high and deep intrinsic stresses with pressure character induced by the finishing process can reduce wear. [German] Die 'Oberflaechenbewertung' wurde im Rahmen des DFG-Schwerpunktprogramms 'Bearbeitungsbedingte Oberflaechenausbildung und tribologische Eigenschaften keramischer Bauteile' innerhalb des Forschungsverbundes 'BOT' (Bearbeitung - Oberflaeche - Tribologie) in Zusammenarbeit mit Projektpartnern durchgefuehrt. Proben aus Hochleistungskeramiken (SSiC, SiSiC, Si{sub 3}N{sub 4}) die von den Projektpartnern mit unterschiedlichen Verfahren (Schleifen, Polieren, Laeppen, Ultraschall-Schwinglaeppen, Funkenerosion und Laserstrahl-Formabtrag) bearbeitet worden waren, wurden im IWM werkstoffmechanisch charakterisiert und im Gleit- bzw. Waelzverschleissversuch geprueft. Die roentgenographische Ermittlung der bearbeitungsbedingten Randschichtveraenderungen und deren Bewertung mittels bruchmechanischer Methoden hat gezeigt, dass bei groben Bearbeitungsverfahren der Einfluss festigkeitssteigernder Bearbeitungs-Eigenspannungen (mit Druckcharakter) den Einfluss bearbeitungsbedingter Schaedigungen ueberwiegen

  12. 76 FR 56318 - Parts and Accessories Necessary for Safe Operation; Saddle-Mount Braking Requirements

    Science.gov (United States)

    2011-09-13

    ... because the lightly loaded axle of the last vehicle tends to lock up under heavy braking. DATES: The final... antilock braking systems. ACC Automobile Carriers Conference. ATA American Trucking Associations. ATC ATC... heavy braking, potentially increasing stopping distance. Stopping distances are specified in the vehicle...

  13. Comparative analysis of the operation efficiency of the continuous and relay control systems of a multi-axle wheeled vehicle suspension

    Science.gov (United States)

    Zhileykin, M. M.; Kotiev, G. O.; Nagatsev, M. V.

    2018-02-01

    In order to improve the efficiency of the multi-axle wheeled vehicles (MWV) automotive engineers are increasing their cruising speed. One of the promising ways to improve ride comfort of the MWV is the development of the dynamic active suspension systems and control laws for such systems. Here, by the dynamic control systems we mean the systems operating in real time mode and using current (instantaneous) values of the state variables. The aim of the work is to develop the MWV suspension optimal control laws that would reduce vibrations on the driver’s seat at kinematic excitation. The authors have developed the optimal control laws for damping the oscillations of the MWV body. The developed laws allow reduction of the vibrations on the driver’s seat and increase in the maximum speed of the vehicle. The laws are characterized in that they allow generating the control inputs in real time mode. The authors have demonstrated the efficiency of the proposed control laws by means of mathematical simulation of the MWV driving over unpaved road with kinematic excitation. The proposed optimal control laws can be used in the MWV suspension control systems with magnetorheological shock absorbers or controlled hydropneumatic springs. Further evolution of the research line can be the development of the energy-efficient MWV suspension control systems with continuous control input on the vehicle body.

  14. The important role of martensite laths to fracture toughness for the ductile fracture controlled by the strain in EA4T axle steel

    International Nuclear Information System (INIS)

    Liang, Yilong; Long, Shaolei; Xu, Pingwei; Lu, Yemao; Jiang, Yun; Liang, Yu; Yang, Ming

    2017-01-01

    The Hall-Petch relationship was used to investigate the role of martensite lath on fracture toughness (K IC ) during ductile fracture in a low-carbon EA4T axle steel. The hierarchical structures of lath martensite was clarified by means of optical microscope (OM), field emission scanning electron microscopy (FESEM), transmission electron microscopy (TEM) and electron backscattering diffraction (EBSD). Firstly, in such hierarchical structures, packet size (d p ) and block size (d b ) increase significantly with the size of prior austenite (d r ), while the martensite lath width (d l ) decreases. Subsequently, K IC was measured and follows the Hall-Petch relationship with d l . It depends on the rotation, bending and direct shear during crack propagation of laths, confirmed by EBSD. Besides, fracture toughness (K IC ) is proportional to a parameter ε v , the matrix strain, which is related to the plastic deformation of laths. Therefore, the martensite lath in hierarchical structures is the effective control unit of K IC during ductile fracture controlled by the strain.

  15. The important role of martensite laths to fracture toughness for the ductile fracture controlled by the strain in EA4T axle steel

    Energy Technology Data Exchange (ETDEWEB)

    Liang, Yilong, E-mail: liangyilong@126.com [College of Materials Science and Metallurgical Engineering, Guizhou University (China); Guizhou key Laboratory for Mechanical Behavior and Microstructure of Materials (China); National & Local Joint Engineering Laboratory for High-performance Metal Structure Material and Advanced Manufacturing Technology (China); Long, Shaolei; Xu, Pingwei; Lu, Yemao [College of Materials Science and Metallurgical Engineering, Guizhou University (China); Guizhou key Laboratory for Mechanical Behavior and Microstructure of Materials (China); National & Local Joint Engineering Laboratory for High-performance Metal Structure Material and Advanced Manufacturing Technology (China); Jiang, Yun [Guizhou key Laboratory for Mechanical Behavior and Microstructure of Materials (China); National & Local Joint Engineering Laboratory for High-performance Metal Structure Material and Advanced Manufacturing Technology (China); Liang, Yu; Yang, Ming [College of Materials Science and Metallurgical Engineering, Guizhou University (China); Guizhou key Laboratory for Mechanical Behavior and Microstructure of Materials (China); National & Local Joint Engineering Laboratory for High-performance Metal Structure Material and Advanced Manufacturing Technology (China)

    2017-05-17

    The Hall-Petch relationship was used to investigate the role of martensite lath on fracture toughness (K{sub IC}) during ductile fracture in a low-carbon EA4T axle steel. The hierarchical structures of lath martensite was clarified by means of optical microscope (OM), field emission scanning electron microscopy (FESEM), transmission electron microscopy (TEM) and electron backscattering diffraction (EBSD). Firstly, in such hierarchical structures, packet size (d{sub p}) and block size (d{sub b}) increase significantly with the size of prior austenite (d{sub r}), while the martensite lath width (d{sub l}) decreases. Subsequently, K{sub IC} was measured and follows the Hall-Petch relationship with d{sub l}. It depends on the rotation, bending and direct shear during crack propagation of laths, confirmed by EBSD. Besides, fracture toughness (K{sub IC}) is proportional to a parameter ε{sub v}, the matrix strain, which is related to the plastic deformation of laths. Therefore, the martensite lath in hierarchical structures is the effective control unit of K{sub IC} during ductile fracture controlled by the strain.

  16. rse, a novel receptor-type tyrosine kinase with homology to Axl/Ufo, is expressed at high levels in the brain.

    Science.gov (United States)

    Mark, M R; Scadden, D T; Wang, Z; Gu, Q; Goddard, A; Godowski, P J

    1994-04-08

    We have isolated cDNA clones that encode the human and murine forms of a novel receptor-type tyrosine kinase termed Rse. Sequence analysis indicates that human Rse contains 890 amino acids, with an extracellular region composed of two immunoglobulin-like domains followed by two fibronectin type III domains. Murine Rse contains 880 amino acids and shares 90% amino acid identity with its human counterpart. Rse is structurally similar to the receptor-type tyrosine kinase Axl/Ufo, and the two proteins have 35 and 63% sequence identity in their extracellular and intracellular domains, respectively. To study the synthesis and activation of this putative receptor-type tyrosine kinase, we constructed a version of Rse (termed gD-Rse, where gD represents glycoprotein D) that contains an NH2-terminal epitope tag. NIH3T3 cells were engineered to express gD-Rse, which could be detected at the cell surface by fluorescence-activated cell sorting. Moreover, gD-Rse was rapidly phosphorylated on tyrosine residues upon incubation of the cells with an antibody directed against the epitope tag, suggesting that rse encodes an active tyrosine kinase. In the human tissues we examined, the highest level of expression of rse mRNA was observed in the brain; rse mRNA was also detected in the premegakaryocytopoietic cell lines CMK11-5 and Dami. The gene for rse was localized to human chromosome 15.

  17. Load sensor

    OpenAIRE

    Van den Ende, D.; Almeida, P.M.R.; Dingemans, T.J.; Van der Zwaag, S.

    2007-01-01

    The invention relates to a load sensor comprising a polymer matrix and a piezo-ceramic material such as PZT, em not bedded in the polymer matrix, which together form a compos not ite, wherein the polymer matrix is a liquid crystalline resin, and wherein the piezo-ceramic material is a PZT powder forming 30-60% by volume of the composite, and wherein the PZT powder forms 40-50% by volume of the composite.

  18. Simulation of pendulum shock experiments on a passenger car front axle; Simulation von Pendelschlagversuchen an einer PKW-Vorderachse

    Energy Technology Data Exchange (ETDEWEB)

    Sporer, L.; Witt, R.; Muehlbauer, R. [BMW Group, Muenchen (Germany)

    2001-07-01

    The contribution describes the development and application of a method for simulating loads resulting from misuse on car body components. The development of the method and its validation by experiments are described, and its application in the development of the BMW-5 series is gone into. [German] Der Beitrag beschreibt die Entwicklung und Anwendung einer Methode zur Simulation von Missbrauchsbelastungen an Fahrwerkskomponenten. Im ersten Abschnitt ist die systematische Entstehung der Methode und die Absicherung der Simulationsergebnisse durch Ersatzversuche dargestellt. In den folgenden Abschnitten steht die Anwendung der Methode in der Fahrwerksentwicklung bei BMW am Beispiel der Vorderachse der aktuellen 5-er Baureihe im Vordergrund. Das Deformationsverhalten einzelner Lenker bzw. die Schadenskette an der gesamten Achse werden sowohl fuer den seitlichen, als auch fuer den frontalen Pendelschlag aufgezeigt. (orig.)

  19. An MHD energy storage system comprising a heavy-water producing electrolysis plant and a H2/O2/CsOH MHD generator/steam turbine combination to provide a means of transferring nuclear reactor energy from the base-load regime into the intermediate-load and peaking regimes

    International Nuclear Information System (INIS)

    Townsend, S.J.; Koziak, W.W.

    1975-01-01

    The concept is presented of the MHD Energy Storage System, comprising a heavy-water producing electrolysis plant for electricity absorption, hydrogen/oxygen storage and a high-efficiency MHD generator/steam turbine unit for electricity production on demand from the grid. The overall efficiency at 56 to 60 percent is comparable to pumped storage hydro, but at only one-half to two-thirds the capital cost and at considerably greater freedom of location. The MHD Energy Storage System combined with the CANDU nuclear reactor in Canadian use can supply all-nuclear energy to the grid at a unit energy cost lower than when oil or coal fired plants are used in the same grid

  20. Soil heavy metals

    Energy Technology Data Exchange (ETDEWEB)

    Sherameti, Irena [Jena Univ. (Germany). Inst. fuer Allgemeine Botanik und Pflanzenphysiologie; Varma, Ajit (eds.) [Amity Univ., Uttar Pradesh (India). Amity Inst. of Microbial Technology; Amity Science, Technology and Innovation Foundation, Noida, UP (India)

    2010-07-01

    Human activities have dramatically changed the composition and organisation of soils. Industrial and urban wastes, agricultural application and also mining activities resulted in an increased concentration of heavy metals in soils. How plants and soil microorganisms cope with this situation and the sophisticated techniques developed for survival in contaminated soils is discussed in this volume. The topics presented include: the general role of heavy metals in biological soil systems; the relation of inorganic and organic pollutions; heavy metal, salt tolerance and combined effects with salinity; effects on abuscular mycorrhizal and on saprophytic soil fungi; heavy metal resistance by streptomycetes; trace element determination of environmental samples; the use of microbiological communities as indicators; phytostabilization of lead polluted sites by native plants; effects of soil earthworms on removal of heavy metals and the remediation of heavy metal contaminated tropical land. (orig.)

  1. The G6 - a heavy-duty six-wheeled shunting locomotive; Dreiachsige Hochleistungsrangierlokomotive G6

    Energy Technology Data Exchange (ETDEWEB)

    Hildebrandt, Tim [Vossloh Locomotives GmbH, Kiel (Germany). Entwicklung und Standardisierung

    2009-03-15

    With the three-axle shunter G6, exhibited at Innotrans 2008, the renowned producer of rail vehicles Vossloh Locomotives GmbH marks the beginning of a generational change - not only for three-axle but also for four-axle locomotives. In order to replace the type G765C the G6 has been developed in close cooperation with potential customers. Their request concerning robustness and reliability as well as the equipment options set standards for central driver's cab locomotives in general and lead the way for future four-axle replacements within the Vossloh product family. (orig.)

  2. Heavy-ion targets

    International Nuclear Information System (INIS)

    Adair, H.L.; Kobisk, E.H.

    1985-01-01

    This chapter examines the characteristics of targets required in heavy-ion accelerator physics experiments. The effects of target parameters on heavy-ion experimental results are reviewed. The target fabrication and characterization techniques used to minimize experimental problems during heavy-ion bombardment are described. Topics considered include target thickness and uniformity, target lifetime, target purity, substrate materials, Doppler shift effects, metal preparations, and target preparation methods

  3. Heavy quark masses

    Science.gov (United States)

    Testa, Massimo

    1990-01-01

    In the large quark mass limit, an argument which identifies the mass of the heavy-light pseudoscalar or scalar bound state with the renormalized mass of the heavy quark is given. The following equation is discussed: m(sub Q) = m(sub B), where m(sub Q) and m(sub B) are respectively the mass of the heavy quark and the mass of the pseudoscalar bound state.

  4. Heavy quark effective theory and study of heavy hadron spectra

    International Nuclear Information System (INIS)

    Dong Yubing

    1995-01-01

    By employing the heavy quark effective theory, the spectra of heavy hadrons, such as heavy mesons (Q-barq), heavy baryons (QQq and Qqq) and heavy multiquark systems (Q-barQ-barqq) are studied systemically. The results are compared with the predictions for Q-barQ-barqq in potential model

  5. Heavy baryon transitions and the heavy quark effective theory

    International Nuclear Information System (INIS)

    Hussain, F.

    1992-01-01

    Heavy baryon decays are studied in the context of the Bethe-Salpeter approach to the heavy quark effective theory. A drastic reduction, in the number of independent form factors, is found. Results are presented both for heavy to heavy and heavy to light baryon decays. (orig.)

  6. Heavy ion physics

    International Nuclear Information System (INIS)

    Kalpakchieva, R.; Cherepanov, E.A.

    1993-01-01

    The international school-seminar on heavy ion physics had been organized in Dubna in may of 1993. The scientific program of reports covers the following main topics: synthesis and properties of heavy nuclei; synthesis and investigation of properties of exotic nuclei; experiments with radioactive nuclear beams; interaction between complex nuclei at low and intermediate energies. It also includes reports on laser spectroscopy and exotic nuclear beams, on some application of heavy ion beams for the problems of solid state physics, on construction of multidetector facilities and on developing of heavy ion accelerator complexes. Short communication

  7. Heavy-ion radiography

    International Nuclear Information System (INIS)

    Fabrikant, J.I.; Tobias, C.A.; Holley, W.R.; Benton, E.V.; Woodruff, K.H.; MacFarland, E.W.

    1983-01-01

    High energy, heavy-ion beams offer superior discrimination of tissue electron densities at very low radiation doses. This characteristic has potential for diagnostic medical imaging of neoplasms arising in the soft tissues and organs because it can detect smaller inhomogeneities than x rays. Heavy-ion imaging may also increase the accuracy of cancer radiotherapy planning involving use of accelerated charged particles. In the current physics research program of passive heavy-ion imaging, critical modulation transfer function tests are being carried out in heavy-ion projection radiography and heavy-ion computerized tomography. The research goal is to improve the heavy-ion imaging method until it reaches the limits of its theoretical resolution defined by range straggling, multiple scattering, and other factors involved in the beam quality characteristics. Clinical uses of the imaging method include the application of heavy-ion computerized tomography to heavy-ion radiotherapy planning, to the study of brain tumors and other structures of the head, and to low-dose heavy-ion projection mammography, particularly for women with dense breasts where other methods of diagnosis fail. The ions used are primarily 300 to 570 MeV/amu carbon and neon ions accelerated at the Lawrence Berkeley Laboratory Bevalac

  8. Production of heavy water

    Science.gov (United States)

    Spencer, Larry S.; Brown, Sam W.; Phillips, Michael R.

    2017-06-06

    Disclosed are methods and apparatuses for producing heavy water. In one embodiment, a catalyst is treated with high purity air or a mixture of gaseous nitrogen and oxygen with gaseous deuterium all together flowing over the catalyst to produce the heavy water. In an alternate embodiment, the deuterium is combusted to form the heavy water. In an alternate embodiment, gaseous deuterium and gaseous oxygen is flowed into a fuel cell to produce the heavy water. In various embodiments, the deuterium may be produced by a thermal decomposition and distillation process that involves heating solid lithium deuteride to form liquid lithium deuteride and then extracting the gaseous deuterium from the liquid lithium deuteride.

  9. A Noise-Insensitive Semi-Active Air Suspension for Heavy-Duty Vehicles with an Integrated Fuzzy-Wheelbase Preview Control

    Directory of Open Access Journals (Sweden)

    Zhengchao Xie

    2013-01-01

    Full Text Available Semi-active air suspension is increasingly used on heavy-duty vehicles due to its capabilities of consuming less power and low cost and providing better ride quality. In this study, a new low cost but effective approach, fuzzy-wheelbase preview controller with wavelet denoising filter (FPW, is developed for semi-active air suspension system. A semi-active suspension system with a rolling lobe air spring is firstly modeled and a novel front axle vertical acceleration-based road prediction model is constructed. By adopting a sensor on the front axle, the road prediction model can predict more reliable road information for the rear wheel. After filtering useless signal noise, the proposed FPW can generate a noise-insensitive control damping force. Simulation results show that the ride quality, the road holding, the handling capability, the road friendliness, and the comprehensive performance of the semi-active air suspension with FPW outperform those with the traditional active suspension with PID-wheelbase preview controller (APP. It can also be seen that, with the addition of the wavelet filter, the impact of sensor noise on the suspension performance can be minimized.

  10. Heavy metal exposure in patients suffering from electromagnetic hypersensitivity

    Energy Technology Data Exchange (ETDEWEB)

    Ghezel-Ahmadi, David, E-mail: david.ahmadi@web.de [Department of Psychiatry, University of Mainz (Germany); Engel, Alice; Weidemann, Joerg [Department of Psychiatry, University of Mainz (Germany); Budnik, Lygia Therese; Baur, Xaver [Institute for Occupational Medicine and Maritime Medicine (ZfAM), University of Hamburg (Germany); Frick, Ulrich [Department of Psychiatry, University of Regensburg (Germany); Department of Healthcare Management, Carinthia University of Applied Sciences (Austria); Hauser, Simone [Department of Psychiatry, University of Regensburg (Germany); Dahmen, Norbert [Department of Psychiatry, University of Mainz (Germany)

    2010-01-15

    Background: Risks from electromagnetic devices are of considerable concern. Electrohypersensitive (EHS) persons attribute a variety of rather unspecific symptoms to the exposure to electromagnetic fields. The pathophysiology of EHS is unknown and therapy remains a challenge. Objectives: Heavy metal load has been discussed as a potential factor in the symptomatology of EHS patients. The main objective of the study was to test the hypothesis of a link between EHS and heavy metal exposure. Methods: We measured lead, mercury and cadmium concentrations in the blood of 132 patients (n = 42 males and n = 90 females) and 101 controls (n = 34 males and n = 67 females). Results: Our results show that heavy metal load is of no concern in most cases of EHS but might play a role in exceptional cases. Conclusions: The data do not support the general advice to heavy metal detoxification in EHS.

  11. Biomonitoring of heavy metals: Definitions, possibilities and limitations

    International Nuclear Information System (INIS)

    Markert, B.; Oehlmann, J.; Roth, M.

    2000-01-01

    Increasing attention given to heavy metals as components of the pollutant load in ecosystems makes it necessary to find reliable biological indicators. Fundamental investigations into the effect of heavy metals on organisms are therefore required. Different organisms (mosses, snails, etc.) were chosen as indicator organisms to optimize the indication of heavy metal loads at the physiological and biochemical level. All current programmes are designed to observe and measure pollutant inputs on a short or long-term basis. However, the changes in the environment of a phenological, physiological, sociological, genetic and physiological/biochemical nature have been investigated by biologists since the beginning of biological scientific research. So far excellent scientific results have been produced by qualification of the heavy metal status in ecosystems. Until now, the quantification of the results with regard to pollutant inputs in ecosystems (mass balances) and their action in these ecosystems have been investigated inadequately. (author)

  12. Heavy metal exposure in patients suffering from electromagnetic hypersensitivity

    International Nuclear Information System (INIS)

    Ghezel-Ahmadi, David; Engel, Alice; Weidemann, Joerg; Budnik, Lygia Therese; Baur, Xaver; Frick, Ulrich; Hauser, Simone; Dahmen, Norbert

    2010-01-01

    Background: Risks from electromagnetic devices are of considerable concern. Electrohypersensitive (EHS) persons attribute a variety of rather unspecific symptoms to the exposure to electromagnetic fields. The pathophysiology of EHS is unknown and therapy remains a challenge. Objectives: Heavy metal load has been discussed as a potential factor in the symptomatology of EHS patients. The main objective of the study was to test the hypothesis of a link between EHS and heavy metal exposure. Methods: We measured lead, mercury and cadmium concentrations in the blood of 132 patients (n = 42 males and n = 90 females) and 101 controls (n = 34 males and n = 67 females). Results: Our results show that heavy metal load is of no concern in most cases of EHS but might play a role in exceptional cases. Conclusions: The data do not support the general advice to heavy metal detoxification in EHS.

  13. Requirement of Gamma-Carboxyglutamic Acid Modification and Phosphatidylserine Binding for the Activation of Tyro3, Axl, and Mertk Receptors by Growth Arrest-Specific 6

    Directory of Open Access Journals (Sweden)

    Ke Geng

    2017-11-01

    Full Text Available The Tyro3, Axl, and Mertk (TAM receptors are homologous type I receptor tyrosine kinases that have critical functions in the clearance of apoptotic cells in multicellular organisms. TAMs are activated by their endogenous ligands, growth arrest-specific 6 (Gas6, and protein S (Pros1, that function as bridging molecules between externalized phosphatidylserine (PS on apoptotic cells and the TAM ectodomains. However, the molecular mechanisms by which Gas6/Pros1 promote TAM activation remains elusive. Using TAM/IFNγR1 reporter cell lines to monitor functional TAM activity, we found that Gas6 activity was exquisitely dependent on vitamin K-mediated γ-carboxylation, whereby replacing vitamin K with anticoagulant warfarin, or by substituting glutamic acid residues involved in PS binding, completely abrogated Gas6 activity as a TAM ligand. Furthermore, using domain and point mutagenesis, Gas6 activity also required both an intact Gla domain and intact EGF-like domains, suggesting these domains function cooperatively in order to achieve TAM activation. Despite the requirement of γ-carboxylation and the functional Gla domain, non-γ-carboxylated Gas6 and Gla deletion/EGF-like domain deletion mutants still retained their ability to bind TAMs and acted as blocking decoy ligands. Finally, we found that distinct sources of PS-positive cells/vesicles (including apoptotic cells, calcium-induced stressed cells, and exosomes bound Gas6 and acted as cell-derived or exosome-derived ligands to activate TAMs. Taken together, our findings indicate that PS is indispensable for TAM activation by Gas6, and by inference, provides new perspectives on how PS, regulates TAM receptors and efferocytosis.

  14. Heavy-Quark Production

    CERN Document Server

    Frixione, Stefano; Nason, Paolo; Ridolfi, Giovanni

    1997-01-01

    We review the present theoretical and experimental status of heavy quark production in high-energy collisions. In particular, we cover hadro- and photoproduction at fixed target experiments, at HERA and at the hadron colliders, as well as aspects of heavy quark production in e+e- collisions at the Z0 peak.

  15. Canadian heavy water production

    International Nuclear Information System (INIS)

    Dahlinger, A.; Lockerby, W.E.; Rae, H.K.

    1977-05-01

    The paper reviews Canadian experience in the production of heavy water, presents a long-term supply projection, relates this projection to the anticipated long-term electrical energy demand, and highlights principal areas for further improvement that form the bulk of our research and development program on heavy water processes

  16. Heavy ion fusion

    International Nuclear Information System (INIS)

    Bangerter, R.O.

    1986-01-01

    This report on the International Symposium on Heavy Ion Fusion held May 27-29, 1986 summarizes the problems and achievements in the areas of targets, accelerators, focussing, reactor studies, and system studies. The symposium participants recognize that there are large uncertainties in Heavy Ion Fusion but many of them are also optimistic that HIF may ultimately be the best approach to fusion

  17. Enhancing roll stability of heavy vehicle by LQR active anti-roll bar control using electronic servo-valve hydraulic actuators

    Science.gov (United States)

    Vu, Van Tan; Sename, Olivier; Dugard, Luc; Gaspar, Peter

    2017-09-01

    Rollover of heavy vehicle is an important road safety problem world-wide. Although rollovers are relatively rare events, they are usually deadly accidents when they occur. The roll stability loss is the main cause of rollover accidents in which heavy vehicles are involved. In order to improve the roll stability, most of modern heavy vehicles are equipped with passive anti-roll bars to reduce roll motion during cornering or riding on uneven roads. However these may be not sufficient to overcome critical situations. This paper introduces the active anti-roll bars made of four electronic servo-valve hydraulic actuators, which are modelled and integrated in a yaw-roll model of a single unit heavy vehicle. The control signal is the current entering the electronic servo-valve and the output is the force generated by the hydraulic actuator. The active control design is achieved solving a linear optimal control problem based on the linear quadratic regulator (LQR) approach. A comparison of several LQR controllers is provided to allow for tackling the considered multi-objective problems. Simulation results in frequency and time domains show that the use of two active anti-roll bars (front and rear axles) drastically improves the roll stability of the single unit heavy vehicle compared with the passive anti-roll bar.

  18. Heavy water and nonproliferation

    International Nuclear Information System (INIS)

    Miller, M.M.

    1980-05-01

    This report begins with a historical sketch of heavy water. The report next assesses the nonproliferation implications of the use of heavy water-moderated power reactors; several different reactor types are discussed, but the focus is on the natural uranium, on-power fueled, pressure tube reactor CANDU. The need for and development of on-power fueling safeguards is discussed. Also considered is the use of heavy water in plutonium production reactors as well as the broader issue of the relative nuclear leverage that suppliers can bring to bear on countries with natural uranium-fueled reactors as compared to those using enriched designs. The final chapter reviews heavy water production methods and analyzes the difficulties involved in implementing these on both a large and a small scale. It concludes with an overview of proprietary and nonproliferation constraints on heavy water technology transfer

  19. Achilles and Patellar Tendinopathy Loading Programmes

    DEFF Research Database (Denmark)

    Malliaras, Peter; Barton, Christian J; Reeves, Neil D

    2013-01-01

    . Eccentric-concentric progressing to eccentric (Silbernagel combined) and eccentric-concentric isotonic (heavy-slow resistance; HSR) loading have also been investigated. In order for clinicians to make informed decisions, they need to be aware of the loading options and comparative evidence. The mechanisms...... mechanism that was consistently associated with improved clinical outcomes in both Achilles and patellar tendon rehabilitation was improved neuromuscular performance (e.g. torque, work, endurance), and Silbernagel-combined (Achilles) HSR loading (patellar) had an equivalent or higher level of evidence than...... isolated eccentric loading. In the Achilles tendon, a majority of studies did not find an association between improved imaging (e.g. reduced anteroposterior diameter, proportion of tendons with Doppler signal) and clinical outcomes, including all high-quality studies. In contrast, HSR loading...

  20. Load testing circuit

    DEFF Research Database (Denmark)

    2009-01-01

    A load testing circuit a circuit tests the load impedance of a load connected to an amplifier. The load impedance includes a first terminal and a second terminal, the load testing circuit comprising a signal generator providing a test signal of a defined bandwidth to the first terminal of the load...

  1. Heavy-ion dosimetry

    International Nuclear Information System (INIS)

    Schimmerling, W.

    1980-03-01

    This lecture deals with some of the more important physical characteristics of relativistic heavy ions and their measurement, with beam delivery and beam monitoring, and with conventional radiation dosimetry as used in the operation of the BEVALAC biomedical facility for high energy heavy ions (Lyman and Howard, 1977; BEVALAC, 1977). Even so, many fundamental aspects of the interaction of relativistic heavy ions with matter, including important atomic physics and radiation chemical considerations, are not discussed beyond the reminder that such additional understanding is required before an adequte perspective of the problem can be attained

  2. Numerical Simulation of the Ground Response to the Tire Load Using Finite Element Method

    Science.gov (United States)

    Valaskova, Veronika; Vlcek, Jozef

    2017-10-01

    Response of the pavement to the excitation caused by the moving vehicle is one of the actual problems of the civil engineering practice. The load from the vehicle is transferred to the pavement structure through contact area of the tires. Experimental studies show nonuniform distribution of the pressure in the area. This non-uniformity is caused by the flexible nature and the shape of the tire and is influenced by the tire inflation. Several tire load patterns, including uniform distribution and point load, were involved in the numerical modelling using finite element method. Applied tire loads were based on the tire contact forces of the lorry Tatra 815. There were selected two procedures for the calculations. The first one was based on the simplification of the vehicle to the half-part model. The characteristics of the vehicle model were verified by the experiment and by the numerical model in the software ADINA, when vehicle behaviour during the ride was investigated. Second step involved application of the calculated contact forces for the front axle as the load on the multi-layered half space representing the pavement structure. This procedure was realized in the software Plaxis and considered various stress patterns for the load. The response of the ground to the vehicle load was then analyzed. Axisymmetric model was established for this procedure. The paper presents the results of the investigation of the contact pressure distribution and corresponding reaction of the pavement to various load distribution patterns. The results show differences in some calculated quantities for different load patterns, which need to be verified by the experimental way when also ground response should be observed.

  3. Critical loads and excess loads of cadmium, copper and lead for European forest soils

    NARCIS (Netherlands)

    Reinds, G.J.; Bril, J.; Vries, de W.; Groenenberg, J.E.; Breeuwsma, A.

    1995-01-01

    Recently, concern has arisen about the impact of the dispersion of heavy metals in Europe. Therefore, a study (ESQUAD) was initiated to assess critical loads and steady-state concentrations of cadmium, copper and lead for European forest soils. The calculation methods used strongly resemble those

  4. Loads and loads and loads: The influence of prospective load, retrospective load, and ongoing task load in prospective memory

    Directory of Open Access Journals (Sweden)

    Beat eMeier

    2015-06-01

    Full Text Available In prospective memory tasks different kinds of load can occur. Adding a prospective memory task can impose a load on ongoing task performance. Adding ongoing task load can affect prospective memory performance. The existence of multiple target events increases prospective load and adding complexity to the to-be-remembered action increases retrospective load. In two experiments, we systematically examined the effects of these different types of load on prospective memory performance. Results showed an effect of prospective load on costs in the ongoing task for categorical targets (Experiment 2, but not for specific targets (Experiment 1. Retrospective load and ongoing task load both affected remembering the retrospective component of the prospective memory task. We suggest that prospective load can enhance costs in the ongoing task due to additional monitoring requirements. Retrospective load and ongoing task load seem to impact the division of resources between the ongoing task and retrieval of the retrospective component, which may affect disengagement from the ongoing task. In general, the results demonstrate that the different types of load affect prospective memory differentially.

  5. Transport of heavy load radioactive material in Germany

    Energy Technology Data Exchange (ETDEWEB)

    Sigmund, W.; Koelpin, E. [Nuclear Cargo and Service GmbH, Hanau (Germany)

    2004-07-01

    Nuclear generation has become over the last 4 decades a vital part of Germany's energetic fundament and is contributing to roughly one third of the overall electric generation (Figures of 2003: 31.7%, i. e. 156.4 thou. GWh nuclear of 493.3 thou. GWh generated in total). And anyone who seriously tries to look beyond the outlet sockets on the wall when considering an economic reasonable energy supply which moreover is sustainable past the foreseeable exhaustion date of fossil fuels (which, in turn, will gain in value in the decades to come as raw material in chemistry) as well as environmental friendly without carbon dioxide emission, reliable and safe - must inevitably come to conclusions that oppose that ''zeitgeist stand'' and unsubstantiated ''green dogma'' to depart from all forms of nuclear generation.

  6. Transport of heavy load radioactive material in Germany

    International Nuclear Information System (INIS)

    Sigmund, W.; Koelpin, E.

    2004-01-01

    Nuclear generation has become over the last 4 decades a vital part of Germany's energetic fundament and is contributing to roughly one third of the overall electric generation (Figures of 2003: 31.7%, i. e. 156.4 thou. GWh nuclear of 493.3 thou. GWh generated in total). And anyone who seriously tries to look beyond the outlet sockets on the wall when considering an economic reasonable energy supply which moreover is sustainable past the foreseeable exhaustion date of fossil fuels (which, in turn, will gain in value in the decades to come as raw material in chemistry) as well as environmental friendly without carbon dioxide emission, reliable and safe - must inevitably come to conclusions that oppose that ''zeitgeist stand'' and unsubstantiated ''green dogma'' to depart from all forms of nuclear generation

  7. Assessment of toxic heavy metal loading in topsoil samples within ...

    African Journals Online (AJOL)

    gilly

    600. 91. 22. 87. -. 50. CCME (1999). Canada (residential). 140. 63. 10. 64. -. 50. CCME (1999) .... an automobile battery manufacturing plant in Nigeria. Afri. J. Environ. Sci. ... Copper, Nickel, and Zinc in Contaminated Soils. J. Environ. Qual.

  8. HEAVY METALS LOAD IN TILAPIA SPECIES: A CASE STUDY OF ...

    African Journals Online (AJOL)

    DR. AMINU

    developing countries (Lloyd, 1992) due to their toxicity and threat to ... further the metal toxicity (Dimari et al., 2008). Water borne ... Kusalla dam so as to evaluate their safety for human .... of metals like chromium, cadmium, copper and zinc is.

  9. Phenomenology of heavy leptons and heavy quarks

    International Nuclear Information System (INIS)

    Gilman, F.J.

    1978-11-01

    The review of the quark and lepton family includes properties of the tau, SU(2) x U(1) classification of the tau and its decays, heavier leptons, the spectroscopy of heavy hadrons composed of quarks, their strong and electromagnetic decays, the weak interaction properties of the c, b, and t quarks, and the decays of hadrons containing them expected within the context of the standard SU(2) x U(1) model. 76 references

  10. Heavy Flavour Production

    CERN Document Server

    Nason, Paolo; Ridolfi, Giovanni

    1995-01-01

    We review the status of heavy flavour production in QCD. Comparison of experimental and theoretical results for top and bottom production are given. Selected topics in charm production are also discussed.

  11. Heavy element research

    International Nuclear Information System (INIS)

    Anon.

    1976-01-01

    Heavy element research activities in metallurgy and ceramics during 1976 at Lawrence Berkeley Laboratory are reviewed. Topics include: microstructure, properties and alloy design; ceramic alloy program; high resolution and high voltage electron microscopy; and powder metallurgy

  12. Heavy rain effects

    Science.gov (United States)

    Dunham, R. Earl, Jr.

    1994-01-01

    This paper summarizes the current state of knowledge of the effect of heavy rain on airplane performance. Although the effects of heavy rain on airplane systems and engines are generally known, only recently has the potential aerodynamic effect of heavy rain been recognized. In 1977 the United States Federal Aviation Administration (FAA) conducted a study of 25 aircraft accidents and incidents which occurred between 1964 and 1976 in which low-altitude wind shear could have been a contributing factor. Of the 25 cases (23 approach or landing and 2 take-off) in the study, ten cases had occurred in a rain environment, and in five cases these were classified as intense or heavy rain encounters. These results led to the reconsideration of high-intensity, short-duration rainfall as a potential weather-related aircraft safety hazard, particularly in the take-off and/or approach phases of flight.

  13. Heavy ion accelerators

    International Nuclear Information System (INIS)

    Schmelzer, C.

    1974-01-01

    This review of the present state of work on heavy-ion accelerators pays particular attention to the requirements for nuclear research. It is divided into the following sections: single-particle versus collective acceleration, heavy-ion accelerators, beam quality, and a status report on the UNILAC facility. Among the topics considered are the recycling cyclotron, linacs with superconducting resonators, and acceleration to the GeV/nucleon range. (8 figures, 2 tables) (U.S.)

  14. Heavy oils clean up

    International Nuclear Information System (INIS)

    Collitt, R.

    1997-01-01

    High production, transport and refining costs have long led oil companies to shun heavy crude oils. Advances in the technology of upgrading heavy oils, however, are likely to reduce transport costs and improve the refinery output. Research and development by Venezuela's state oil company, Petroleos de Venezuela (PDVSA), has resulted in a process called Aquaconversion which permits the upgrading of heavy crude oils using a catalyst and the hydrogen from steam. This may be carried out at the wellhead in small low-pressure and relatively inexpensive units. In addition, higher distillate yields of higher value could be produced by revamping the thermal cracking units of refineries to incorporate the new technology. This has generated considerable interest in Venezuela's large extra-heavy crude oil reserves and has led multinational oil companies along with PDVSA to pledge $17 billion to their development. Even at a $2 to $3 per barrel upgrading cost, Venezuela's extra heavy crudes are competitive with lighter oils from other countries. Other major markets for the new technology are likely to be China and Russia, given their own large heavy crude reserves. (UK)

  15. Process for removing heavy metal compounds from heavy crude oil

    Science.gov (United States)

    Cha, Chang Y.; Boysen, John E.; Branthaver, Jan F.

    1991-01-01

    A process is provided for removing heavy metal compounds from heavy crude oil by mixing the heavy crude oil with tar sand; preheating the mixture to a temperature of about 650.degree. F.; heating said mixture to up to 800.degree. F.; and separating tar sand from the light oils formed during said heating. The heavy metals removed from the heavy oils can be recovered from the spent sand for other uses.

  16. A highly efficient and selective polysilsesquioxane sorbent for heavy metal removal

    KAUST Repository

    Duan, Xiaonan; Qi, Genggeng; Wang, Peng; Giannelis, Emmanuel P.

    2012-01-01

    Suited for heavy stuff: An efficient mesoporous sorbent based on a pure ethylendiamine-bridged polysilsesquioxane is presented. This material, with both a high amine loading and a high surface area, is applied for heavy metal ion removal. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  17. A highly efficient and selective polysilsesquioxane sorbent for heavy metal removal

    KAUST Repository

    Duan, Xiaonan

    2012-02-29

    Suited for heavy stuff: An efficient mesoporous sorbent based on a pure ethylendiamine-bridged polysilsesquioxane is presented. This material, with both a high amine loading and a high surface area, is applied for heavy metal ion removal. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  18. Magnetic evidence for heavy metal pollution of topsoil in Shanghai, China

    Science.gov (United States)

    Wang, Guan; Liu, Yuan; Chen, Jiao; Ren, Feifan; Chen, Yuying; Ye, Fangzhou; Zhang, Weiguo

    2018-03-01

    This study presents the results obtained from magnetic susceptibility and heavy metal (Cu, Zn, Pb, and Cr) concentration measurements of soil profiles collected from arable land and urban parks in Baoshan District, an industrial district of Shanghai, China. The study focuses on the investigation of vertical variations in magnetic susceptibilities and heavy metal concentrations and on correlations between magnetic susceptibilities and heavy metal concentrations in soil profiles. The results demonstrate that magnetic enhancement in the surface layer of the soil profile is associated with increased heavy metal pollution. The enrichment factors (EF) and the Tomlinson Pollution Load Index (PLI-EF) are calculated for estimating the level of heavy metal pollution of soil profiles in the study. The significant positive correlations between heavy metal contents, enrichment factors (EF), Tomlinson pollution load index (PLI-CF), modified Tomlinson pollution load index (PLI-EF), and magnetic susceptibility (c) indicate that much of the heavy metal contamination in the study area is linked to combustion derived particulate emissions. The results confirm that the combined magnetic measurement and heavy metal concentration analysis could provide useful information for soil monitoring in urban environments. However, the use of magnetic technique to locate the heavy metal pollution boundary in the soil profile of this studied area should be confirmed by further geochemical analysis.

  19. REMOVAL OF HEAVY-METALS FROM WASTEWATER USING A ...

    African Journals Online (AJOL)

    This work is licensed under the Creative Commons Attribution 4.0 International License. REMOVAL ... containing wastewaters obtained from a tannery and a leather processing industries revealed excellent adsorption efficacies ... the heavy-metal loading in test industrial effluents obtained from a leather industry and from a.

  20. Physicochemical Characteristics and Heavy Metal Levels in Water ...

    African Journals Online (AJOL)

    MICHAEL

    installations and automobiles, petrochemical industries, the glass factory and other product industries. Mining as well as other domestic activities contributes to heavy metal concentration and sediment load within an environment. This is the case with the Ashaka and Ughelli rivers where oil exploratory activities have led to ...

  1. Mean value analysis for polling systems in heavy traffic

    NARCIS (Netherlands)

    Mei, van der R.D.; Winands, E.M.M.; Lenzini, L.; Cruz, R.

    2006-01-01

    In this paper we present a new approach to derive heavy-traffic asymptotics for polling models. We consider the classical cyclic polling model with exhaustive service at each queue, and with general service-time and switch-over time distributions, and study its behavior when the load tends to one.

  2. Heavy traffic analysis of polling models by mean value analysis

    NARCIS (Netherlands)

    Mei, van der R.D.; Winands, E.M.M.

    2008-01-01

    In this paper we present a new approach to derive heavy-traffic asymptotics for polling models. We consider the classical cyclic polling model with exhaustive or gated service at each queue, and with general service-time and switch-over time distributions, and study its behavior when the load tends

  3. A combined loading system integrated with portable winch and polyethylene chutes for loading of timber products

    Directory of Open Access Journals (Sweden)

    H. Hulusi Acar

    2016-01-01

    Full Text Available Truck loading operation is an important task during timber production operations in forestry. In Turkey, approximately 50 million timbers/logs are being produced per year, and then they are loaded into the logging trucks. The timber/logs are transported over the forest roads with an average of one million roundtrips. However, the traditional loading methods using manpower are mostly performed while some part is done by using loading machines which can be very costly and risky. This study aims developing a combined loading system in which heavy logs are loaded into logging trucks by pulling them by a log-line powered by a portable crane within the chute system. The slope of the log-line from ground to logging truck varied between 1% and 25%. Within the each work cycle of loading operation, only one log was loaded by pulling with portable crane. The average loading time was found as 161.8 seconds per cycle, in which 67% of the time was spent on pulling the log into the logging truck. The results indicated that the average pulling speed with crane power was 840.4 m/hr and productivity was calculated as 4.94 m3/hr. The result on system speed and productivity indicated close relations with results from previous studies. The hydraulic grapple loader or cranes are widely used and common loading machines, but they cannot be efficiently used in forestry operations, especially ones having a low timber productivity rate or having low economic value timber. In these conditions, loading methods that are cost efficient and do not require higher production rate should be employed. Therefore, a combined loading system introduced in this study can be a feasible solution for loading operations in those cases. Furthermore, it is believed that this loading system integrated with a portable crane can be cost efficient and time saving solution, as well as ergonomic and safe method in the field.

  4. Distribution load estimation (DLE)

    Energy Technology Data Exchange (ETDEWEB)

    Seppaelae, A; Lehtonen, M [VTT Energy, Espoo (Finland)

    1998-08-01

    The load research has produced customer class load models to convert the customers` annual energy consumption to hourly load values. The reliability of load models applied from a nation-wide sample is limited in any specific network because many local circumstances are different from utility to utility and time to time. Therefore there is a need to find improvements to the load models or, in general, improvements to the load estimates. In Distribution Load Estimation (DLE) the measurements from the network are utilized to improve the customer class load models. The results of DLE will be new load models that better correspond to the loading of the distribution network but are still close to the original load models obtained by load research. The principal data flow of DLE is presented

  5. Distribution load estimation - DLE

    Energy Technology Data Exchange (ETDEWEB)

    Seppaelae, A. [VTT Energy, Espoo (Finland)

    1996-12-31

    The load research project has produced statistical information in the form of load models to convert the figures of annual energy consumption to hourly load values. The reliability of load models is limited to a certain network because many local circumstances are different from utility to utility and time to time. Therefore there is a need to make improvements in the load models. Distribution load estimation (DLE) is the method developed here to improve load estimates from the load models. The method is also quite cheap to apply as it utilises information that is already available in SCADA systems

  6. Distribution load estimation - DLE

    Energy Technology Data Exchange (ETDEWEB)

    Seppaelae, A [VTT Energy, Espoo (Finland)

    1997-12-31

    The load research project has produced statistical information in the form of load models to convert the figures of annual energy consumption to hourly load values. The reliability of load models is limited to a certain network because many local circumstances are different from utility to utility and time to time. Therefore there is a need to make improvements in the load models. Distribution load estimation (DLE) is the method developed here to improve load estimates from the load models. The method is also quite cheap to apply as it utilises information that is already available in SCADA systems

  7. Heavy-ion radiography

    International Nuclear Information System (INIS)

    Fabrikant, J.I.; Tobias, C.A.; Holley, W.R.; Benton, E.V.

    1981-01-01

    Heavy-particle radiography has clinical potential as a newly developed noninvasive low-dose imaging procedure that provides increased resolution of minute density differences in soft tissues of the body. The method utilizes accelerated high-energy ions, primarily carbon and neon, at the Bevalac accelerator at the Lawrence Berkeley Laboratory. The research program for medicine utilizes heavy-ion radiography for low-dose mammography, for treatment planning for cancer patients, and for imaging and accurate densitometry of skeletal structures, brain and spinal neoplasms, and the heart. The potential of heavy-ion imaging, and particularly reconstruction tomography, is now proving to be an adjunct to existing diagnostic imaging procedures in medicine, both for applications to the diagnosis, management and treatment of clinical cancer in man, and for the early detection of small soft-tissue tumors at low radiation dose

  8. Very heavy dark Skyrmions

    International Nuclear Information System (INIS)

    Dick, Rainer

    2017-01-01

    A dark sector with a solitonic component provides a means to circumvent the problem of generically low annihilation cross sections of very heavy dark matter particles. At the same time, enhanced annihilation cross sections are necessary for indirect detection of very heavy dark matter components beyond 100 TeV. Non-thermally produced dark matter in this mass range could therefore contribute to the cosmic γ-ray and neutrino flux above 100 TeV, and massive Skyrmions provide an interesting framework for the discussion of these scenarios. Therefore a Higgs portal and a neutrino portal for very heavy Skyrmion dark matter are discussed. The Higgs portal model demonstrates a dark mediator bottleneck, where limitations on particle annihilation cross sections will prevent a signal from the potentially large soliton annihilation cross sections. This problem can be avoided in models where the dark mediator decays. This is illustrated by the neutrino portal for Skyrmion dark matter. (orig.)

  9. Very heavy dark Skyrmions

    Energy Technology Data Exchange (ETDEWEB)

    Dick, Rainer [University of Saskatchewan, Department of Physics and Engineering Physics, Saskatoon, SK (Canada)

    2017-12-15

    A dark sector with a solitonic component provides a means to circumvent the problem of generically low annihilation cross sections of very heavy dark matter particles. At the same time, enhanced annihilation cross sections are necessary for indirect detection of very heavy dark matter components beyond 100 TeV. Non-thermally produced dark matter in this mass range could therefore contribute to the cosmic γ-ray and neutrino flux above 100 TeV, and massive Skyrmions provide an interesting framework for the discussion of these scenarios. Therefore a Higgs portal and a neutrino portal for very heavy Skyrmion dark matter are discussed. The Higgs portal model demonstrates a dark mediator bottleneck, where limitations on particle annihilation cross sections will prevent a signal from the potentially large soliton annihilation cross sections. This problem can be avoided in models where the dark mediator decays. This is illustrated by the neutrino portal for Skyrmion dark matter. (orig.)

  10. Heavy fermion materials

    International Nuclear Information System (INIS)

    Smith, J.L.; Cooke, D.W.

    1986-01-01

    The heavy-fermion ground state occurs in a few select metallic compounds as a result of interactions between f-electron and conduction-electron spins. A characteristically large electronic heat capacity at low temperature indicates that the effective electron mass of these materials is more than two orders of magnitude greater than that expected for a free-electron metal. This heavy-fermion ground state can become superconducting or antiferromagnetic, exhibiting very unusual properties. These materials and the role of muon spin rotation in their study are briefly discussed

  11. [Relativistic heavy ion research

    International Nuclear Information System (INIS)

    1990-01-01

    At Brookhaven National Laboratory, participation in the E802 Experiment, which is the first major heavy-ion experiment at the BNL-AGS, was the main focus of the group during the past four years. The emphases of the E802 experiment were on (a) accurate particle identification and measurements of spectra over a wide kinematical domain (5 degree LAB < 55 degree, p < 20 GeV/c); and (b) measurements of small-angle two-particle correlations, with event characterization tools: multiplicity array, forward and large-angle calorimeters. This experiment and other heavy ion collision experiments are discussed in this report

  12. Search for heavy particles

    International Nuclear Information System (INIS)

    Barnett, R.M.

    1977-03-01

    Direct and indirect evidence for the existence of a new heavy quark b and of new heavy neutral leptons N/sub e/ and N/sub μ/ can be sought in neutrino and e + e - scattering. These particles are expected to have right-handed currents. Discussion is given on the characteristics, production and decay of hadrons such as bb, ub and db, and of the massive neutral leptons. Muon number violation with and without N/sub e/ and N/sub μ/ is considered

  13. Heavy ion collisions

    International Nuclear Information System (INIS)

    Jacak, B.V.

    1994-01-01

    Heavy ion collisions at very high energies provide an opportunity to recreate in the laboratory the conditions which existed very early in the universe, just after the big bang. We prepare matter at very high energy density and search for evidence that the quarks and gluons are deconfined. I describe the kinds of observables that are experimentally accessible to characterize the system and to search for evidence of new physics. A wealth of information is now available from CERN and BNL heavy ion experiments. I discuss recent results on two particle correlations, strangeness production, and dilepton and direct photon distributions

  14. Critical component wear in heavy duty engines

    CERN Document Server

    Lakshminarayanan, P A

    2011-01-01

    The critical parts of a heavy duty engine are theoretically designed for infinite life without mechanical fatigue failure. Yet the life of an engine is in reality determined by wear of the critical parts. Even if an engine is designed and built to have normal wear life, abnormal wear takes place either due to special working conditions or increased loading.  Understanding abnormal and normal wear enables the engineer to control the external conditions leading to premature wear, or to design the critical parts that have longer wear life and hence lower costs. The literature on wear phenomenon r

  15. The effect of track load correlation on ground-borne vibration from railways

    Science.gov (United States)

    Ntotsios, Evangelos; Thompson, David; Hussein, Mohammed

    2017-08-01

    In predictions of ground-borne vibration from railways, it is generally assumed that the unevenness profile of the wheel and rail is fully correlated between the two rails and the two wheels of an axle. This leads to identical contact forces at the two rails and can allow further simplifications of the vehicle model, the track model and the track/ground interface conditions. In the present paper, the level of correlation of the track loading at the wheel/rail interface due to rail unevenness and its influence on predictions of ground vibration is investigated. The extent to which the unevenness of the two rails is correlated has been estimated from measurements of track geometry obtained with track recording vehicles for four different tracks. It was found that for wavelengths longer than about 3 m the unevenness of the two rails can be considered to be strongly correlated and in phase. To investigate the effect of this on ground vibration, an existing model expressed in the wavenumber-frequency domain is extended to include separate inputs on the two rails. The track is modelled as an infinite invariant linear structure resting on an elastic stratified half-space. This is excited by the gravitational loading of a passing train and the irregularity of the contact surfaces between the wheels and the rails. The railway model is developed in this work to be versatile so that it can account or discard the effect of load correlations on the two rails beside the effects of variation of the tractions across the width of the track-ground interface and the vehicle sprung mass, as well as the roll motion of the sleepers and the axle. A comparative analysis is carried out on the influence of these factors on the response predictions using numerical simulations. It is shown that, when determining the vibration in the free field, it is important to include in the model the traction variation across the track-ground interface and the non-symmetrical loading at the two rails that

  16. Inductrack III configuration--a maglev system for high loads

    Science.gov (United States)

    Post, Richard F

    2013-11-12

    Inductrack III configurations are suited for use in transporting heavy freight loads. Inductrack III addresses a problem associated with the cantilevered track of the Inductrack II configuration. The use of a cantilevered track could present mechanical design problems in attempting to achieve a strong enough track system such that it would be capable of supporting very heavy loads. In Inductrack III, the levitating portion of the track can be supported uniformly from below, as the levitating Halbach array used on the moving vehicle is a single-sided one, thus does not require the cantilevered track as employed in Inductrack II.

  17. Adaptive sliding control of non-autonomous active suspension systems with time-varying loadings

    Science.gov (United States)

    Chen, Po-Chang; Huang, An-Chyau

    2005-04-01

    An adaptive sliding controller is proposed in this paper for controlling a non-autonomous quarter-car suspension system with time-varying loadings. The bound of the car-body loading is assumed to be available. Then, the reference coordinate is placed at the static position under the nominal loading so that the system dynamic equation is derived. Due to spring nonlinearities, the system property becomes asymmetric after coordinate transformation. Besides, in practical cases, system parameters are not easy to be obtained precisely for controller design. Therefore, in this paper, system uncertainties are lumped into two unknown time-varying functions. Since the variation bound of one of the unknown functions is not available, conventional adaptive schemes and robust designs are not applicable. To deal with this problem, the function approximation technique is employed to represent the unknown function as a finite combination of basis functions. The Lyapunov direct method can thus be used to find adaptive laws for updating coefficients in the approximating series and to prove stability of the closed-loop system. Since the position and velocity measurements of the unsprung mass are lumped into the unknown function, there is no need to install sensors on the axle and wheel assembly in the actual implementation. Simulation results are presented to show the performance of the proposed strategy.

  18. Heavy baryons in the heavy quark effective theory

    International Nuclear Information System (INIS)

    Koerner, J.G.; Thompson, G.

    1991-10-01

    We give a mini-review of recent results on current-induced transitions between heavy baryons (and between heavy and light baryons) in the light of the new spin and flavour symmetries of the Heavy Quark Effective Theory (HQET). We discuss the structure of the 1/m corrections to the heavy mass limit and outline a diagrammatic proof that there are no 0(1/m) correction to the Voloshin-Shifman normalization condition at zero recoil. (orig.)

  19. Heavy ion accelerator GANIL

    International Nuclear Information System (INIS)

    1975-04-01

    This article presents GANIL, a large national heavy ion accelerator. The broad problems of nuclear physics, atomic physics, astrophysics and physics of condensed media which can be approached and studied with this machine are discussed first, after which the final construction project is described. The project comprises a circular injector, a separated sector cyclotron up beam stripper, and a second separated cyclotron downstream [fr

  20. Heavy liquid bubble chamber

    CERN Multimedia

    CERN PhotoLab

    1965-01-01

    The CERN Heavy liquid bubble chamber being installed in the north experimental hall at the PS. On the left, the 1180 litre body; in the centre the magnet, which can produce a field of 26 800 gauss; on the right the expansion mechanism.

  1. Heavy quarks photoproduction

    International Nuclear Information System (INIS)

    Cacciari, M.

    1996-08-01

    The state of the art of the theoretical calculations for heavy quarks photoproduction is reviewed. The full next-to-leading order calculation and two possible resummations, the high energy one for total cross sections and the large p T one for differential cross sections, are described. (orig.)

  2. Bioaccumulation of Heavy Metals

    African Journals Online (AJOL)

    komla

    acute toxicity and sublethal chronic action the devastating effects that the accumulation - including ... the laboratory and kept in holding glass (a) Copper as CuSO,.5H,0 ... from 2 psu to 21 psu) depending on time of The choice of heavy metals for this s year. ... serving as substrate and food source for Salinity of test media.

  3. Heavy-ion microscopy

    International Nuclear Information System (INIS)

    Kraft, G.; Yang, T.C.H.; Richards, T.; Tobias, C.A.

    1980-01-01

    This chapter briefly describes the techniques of optical microscopy, scanning and transmission electron microscopy, soft x-ray microscopy and compares these latter techniques with heavy-ion microscopy. The resolution obtained with these various types of microscopy are compared and the influence of the etching procedure on total resolution is discussed. Several micrographs of mammalian cells are included

  4. Heavy chain only antibodies

    DEFF Research Database (Denmark)

    Moghimi, Seyed Moein; Rahbarizadeh, Fatemeh; Ahmadvand, Davoud

    2013-01-01

    Unlike conventional antibodies, heavy chain only antibodies derived from camel contain a single variable domain (VHH) and two constant domains (CH2 and CH3). Cloned and isolated VHHs possess unique properties that enable them to excel conventional therapeutic antibodies and their smaller antigen...

  5. Relativisitic heavy ion collisions

    International Nuclear Information System (INIS)

    Tannenbaum, M.J.

    1987-01-01

    Some of the objectives and observables of Relativistic Heavy Ion Physics are presented. The first experimental results from oxygen interactions at CERN, 200 GeV/c per nucleon, and BNL, 14.5 GeV/c per nucleon are shown. The data indicate more energy emission than was originally predicted. 25 refs., 19 figs

  6. Heavy-ion radiography and heavy-ion computed tomography

    International Nuclear Information System (INIS)

    Fabrikant, J.I.; Holley, W.R.; McFarland, E.W.; Tobias, C.a.

    1982-02-01

    Heavy-ion projection and CT radiography is being developed into a safe, low-dose, noninvasive radiological procedure that can quantitate and image small density differences in human tissues. The applications to heavy-ion mammography and heavy-ion CT imaging of the brain in clinical patients suggest their potential value in cancer diagnosis

  7. Shot loading platform analysis

    International Nuclear Information System (INIS)

    Norman, B.F.

    1994-01-01

    This document provides the wind/seismic analysis and evaluation for the shot loading platform. Hand calculations were used for the analysis. AISC and UBC load factors were used in this evaluation. The results show that the actual loads are under the allowable loads and all requirements are met

  8. Assessing potential dietary toxicity of heavy metals in selected vegetables and food crops.

    Science.gov (United States)

    Islam, Ejaz ul; Yang, Xiao-e; He, Zhen-li; Mahmood, Qaisar

    2007-01-01

    Heavy metals, such as cadmium, copper, lead, chromium and mercury, are important environmental pollutants, particularly in areas with high anthropogenic pressure. Their presence in the atmosphere, soil and water, even in traces can cause serious problems to all organisms, and heavy metal bioaccumulation in the food chain especially can be highly dangerous to human health. Heavy metals enter the human body mainly through two routes namely: inhalation and ingestion, ingestion being the main route of exposure to these elements in human population. Heavy metals intake by human populations through food chain has been reported in many countries. Soil threshold for heavy metal toxicity is an important factor affecting soil environmental capacity of heavy metal and determines heavy metal cumulative loading limits. For soil-plant system, heavy metal toxicity threshold is the highest permissible content in the soil (total or bioavailable concentration) that does not pose any phytotoxic effects or heavy metals in the edible parts of the crops does not exceed food hygiene standards. Factors affecting the thresholds of dietary toxicity of heavy metal in soil-crop system include: soil type which includes soil pH, organic matter content, clay mineral and other soil chemical and biochemical properties; and crop species or cultivars regulated by genetic basis for heavy metal transport and accumulation in plants. In addition, the interactions of soil-plant root-microbes play important roles in regulating heavy metal movement from soil to the edible parts of crops. Agronomic practices such as fertilizer and water managements as well as crop rotation system can affect bioavailability and crop accumulation of heavy metals, thus influencing the thresholds for assessing dietary toxicity of heavy metals in the food chain. This paper reviews the phytotoxic effects and bioaccumulation of heavy metals in vegetables and food crops and assesses soil heavy metal thresholds for potential dietary

  9. Heavy quarks - experimental

    International Nuclear Information System (INIS)

    Hollebeek, R.

    1990-01-01

    The purpose of these lectures, given at the 1989 SLAC Summer School, was to discuss the experimental aspects of heavy quark production. A companion set of lectures on the theoretical point of view were to be given by Keith Ellis. An experimentalist should gather together the measurements which have been made by various groups, compare, contrast and tabulate them, and if possible point out the ways in which these measurements confirm or contradict current theories. Here the authors has tried to do this, although the reader who expects to find here the latest of all experimental measurements should probably be forewarned that the field is moving extremely rapidly. In some cases, he has added and updated materials where crucial new information became available after or during the summer of 1989, but not in all cases. He has concentrated on trying to select those measurements which are at the moment most crucial in refining our understanding of heavy quarks as opposed to those which merely measure things which are perhaps too complicated to be enlightening at the moment. While theorists worry primarily about production mechanisms, cross sections, QCD corrections, and to some extent about signatures, the experimentalist must determine which measurements he is interested in making, and which signatures for heavy quark production are realistic and likely to produce results which will shed some new light on the underlying production model without undo theoretical complications. Experimentalists also need to evaluate the available experimental equipment, both machines and detectors to find the best way to investigate the properties of heavy quarks. In many cases, the things which we would like to measure are severely restricted by what we can measure. Nevertheless, many properties of heavy quark production and decay can be measured, and the results have already taught us much about the weak interactions and QCD

  10. Heavy water at Aswan

    International Nuclear Information System (INIS)

    1959-01-01

    A fertilizer factory is being built by Egyptian Chemical Industries (Kima) at Aswan on the upper Nile; it will produce a mixture of ammonium nitrate and calcium carbonate adjusted to contain 20.5% nitrogen. It is also proposed to construct a heavy water plant to be located at and integrated with the fertilizer factory. At the request of the Government of the United Arab Republic, the International Atomic Energy Agency sent an expert to carry out investigation of the technical, economic and other related aspects of the proposed production of heavy water. A report was submitted to the IAEA Director General. Its main conclusions can be summarized as follows: (1) Production of heavy water as a by-product of fertilizer manufacture at Aswan is technically feasible. Separation of deuterium from industrial hydrogen for this purpose could be done either by catalytic exchange or by liquefaction and distillation; the choice should depend on economic considerations. (2) The heavy water produced at Aswan should be competitive in cost with that produced elsewhere; this, however, would depend on whether firm contracts are obtained for the delivery of equipment at guaranteed prices and with guaranteed performance, and whether such prices are in reasonable agreement with preliminary estimates. (3) The future market for heavy water is difficult to predict. For one thing, there is a very large production capacity in the USA, most of which is idle due to lack of demand. Secondly, there is a relatively small production outside the USA that is sold at prices higher than that charged by the US Government. The future of the market is necessarily contingent upon the possibility of future free sale by the US Government. At the end of his report, the expert has also given his comments on possible further assistance to the project by IAEA

  11. Heavy Flavour Production at HERA

    International Nuclear Information System (INIS)

    Bailey, D.

    2001-01-01

    ZEUS and H1 results on heavy quark production using the HERA data from 1995 to 2000 are summarised with emphasis on unresolved problems. The HERA upgrade and its impact on future heavy flavour measurements is briefly discussed

  12. (17) ACCUMULATION OF HEAVY METAL

    African Journals Online (AJOL)

    Adeyinka Odunsi

    Spectrophotometer (AAS) 2ID using their respective lamp and wavelengths. Calculation ... (Table 2). Concentration of heavy metals in the cassava. Lead and chromium were not significantly ..... Market basket survey for some heavy metals in ...

  13. Contamination by urban superficial runoff: accumulated heavy metals on a road surface

    Directory of Open Access Journals (Sweden)

    Carlos Alfonso Zafra Mejía

    2007-01-01

    Full Text Available Studying the behaviour of accumulated contamination on urban surfaces is important in designing control methods minimising the impacts of surface runoff on the environment. This paper presents data regarding the sediment collected on the surface of an urban road in the city of Torrelavega in northern Spain during a period of 65 days during which 132 samples were collected. Two types of sediment collection samples were obtained: vacuumed dry samples (free load and those swept up following vacuuming (fixed load. The results showed that heavy metal concentration in the collected sediment (Pb, Zn, Cu and Cd was inversely proportional to particle diameter. High heavy metal concentrations were found in the smaller fraction (63 pm. Regression equations were calculated for heavy metal concentration regarding particle diameter. Large heavy metal loads were found in the larger fraction (125 pm. The results provide information for analysing runoff water quality in urban areas and designing treatment strategies.

  14. System and method to allow a synchronous motor to successfully synchronize with loads that have high inertia and/or high torque

    Science.gov (United States)

    Melfi, Michael J.

    2015-10-20

    A mechanical soft-start type coupling is used as an interface between a line start, synchronous motor and a heavy load to enable the synchronous motor to bring the heavy load up to or near synchronous speed. The soft-start coupling effectively isolates the synchronous motor from the load for enough time to enable the synchronous motor to come up to full speed. The soft-start coupling then brings the load up to or near synchronous speed.

  15. Tar loads on Omani beaches

    International Nuclear Information System (INIS)

    Badawy, M.I.; Al-Harthy, F.T.

    1991-01-01

    Owing to Oman's geographic position and long coastal line, the coastal areas of Oman are particularly vulnerable to oil pollution from normal tanker operations, illegal discharges, and accidental spills as well as local sources of oil input. UNEP carried out a survey on the coasts of Oman to determine the major sources of oil pollution and concluded that the major shoreline pollution problems in Oman arose from operational discharges of oil from passing vessels traffic. The oil, because of the high sea and air temperatures in the area, was subjected to relatively high rates of evaporation and photo-oxidation and tended to arrive at the coast as heavy petroleum particulate residues (tar balls). The aim of the present study was to measure the loads of tar balls in Omani coastal areas and to identify the source of oil pollutants on beaches

  16. Heavy water upgrader of 'Fugen'

    International Nuclear Information System (INIS)

    Matsushita, Tadashi; Sasaki, Shigeo

    1980-01-01

    The nuclear power station of the advanced thermal prototype reactor ''Fugen'' has continued the smooth operation since it started the fullscale operation in March, 1979. Fugen is the first heavy water-moderated, boiling light water-cooled reactor in Japan, and its outstanding feature is the use of heavy water as the moderator. The quantity of heavy water retained in Fugen is about 140 m 3 , and the concentration is 99.8 wt.%. This heavy water had been made is USA, and was imported from F.R. of Germany where it had been used. Heavy water is an internationally regulated material, and it is very expensive and hard to purchase. Therefore in order to prevent the deterioration of heavy water and to avoid its loss as far as possible, the management of the quantity and the control of the water quality have been carried out carefully and strictly. The generation of deteriorated heavy water occurs from the exchange of ion exchange resin for poison removal and purification. The heavy water upgrader reconcentrates the deteriorated heavy water of high concentration and returns to the heavy water system, and it was installed for the purpose of reducing the purchase of supplementary heavy water. The outline of the heavy water upgrader, its construction, the performance test and the operation are described. (Kako, I.)

  17. Locomotive Schedule Optimization for Da-qin Heavy Haul Railway

    Directory of Open Access Journals (Sweden)

    Ruiye Su

    2015-01-01

    Full Text Available The main difference between locomotive schedule of heavy haul railways and that of regular rail transportation is the number of locomotives utilized for one train. One heavy-loaded train usually has more than one locomotive, but a regular train only has one. This paper develops an optimization model for the multilocomotive scheduling problem (MLSP through analyzing the current locomotive schedule of Da-qin Railway. The objective function of our paper is to minimize the total number of utilized locomotives. The MLSP is nondeterministic polynomial (NP hard. Therefore, we convert the multilocomotive traction problem into a single-locomotive traction problem. Then, the single-locomotive traction problem (SLTP can be converted into an assignment problem. The Hungarian algorithm is applied to solve the model and obtain the optimal locomotive schedule. We use the variance of detention time of locomotives at stations to evaluate the stability of locomotive schedule. In order to evaluate the effectiveness of the proposed optimization model, case studies for 20 kt and 30 kt heavy-loaded combined trains on Da-qin Railway are both conducted. Compared to the current schedules, the optimal schedules from the proposed models can save 62 and 47 locomotives for 20 kt and 30 kt heavy-loaded combined trains, respectively. Therefore, the effectiveness of the proposed model and its solution algorithm are both valid.

  18. Loads and loads and loads: the influence of prospective load, retrospective load, and ongoing task load in prospective memory

    Science.gov (United States)

    Meier, Beat; Zimmermann, Thomas D.

    2015-01-01

    In prospective memory tasks different kinds of load can occur. Adding a prospective memory task can impose a load on ongoing task performance. Adding ongoing task load (OTL) can affect prospective memory performance. The existence of multiple target events increases prospective load (PL) and adding complexity to the to-be-remembered action increases retrospective load (RL). In two experiments, we systematically examined the effects of these different types of load on prospective memory performance. Results showed an effect of PL on costs in the ongoing task for categorical targets (Experiment 2), but not for specific targets (Experiment 1). RL and OTL both affected remembering the retrospective component of the prospective memory task. We suggest that PL can enhance costs in the ongoing task due to additional monitoring requirements. RL and OTL seem to impact the division of resources between the ongoing task and retrieval of the retrospective component, which may affect disengagement from the ongoing task. In general, the results demonstrate that the different types of load affect prospective memory differentially. PMID:26082709

  19. Loads and loads and loads: the influence of prospective load, retrospective load, and ongoing task load in prospective memory.

    Science.gov (United States)

    Meier, Beat; Zimmermann, Thomas D

    2015-01-01

    In prospective memory tasks different kinds of load can occur. Adding a prospective memory task can impose a load on ongoing task performance. Adding ongoing task load (OTL) can affect prospective memory performance. The existence of multiple target events increases prospective load (PL) and adding complexity to the to-be-remembered action increases retrospective load (RL). In two experiments, we systematically examined the effects of these different types of load on prospective memory performance. Results showed an effect of PL on costs in the ongoing task for categorical targets (Experiment 2), but not for specific targets (Experiment 1). RL and OTL both affected remembering the retrospective component of the prospective memory task. We suggest that PL can enhance costs in the ongoing task due to additional monitoring requirements. RL and OTL seem to impact the division of resources between the ongoing task and retrieval of the retrospective component, which may affect disengagement from the ongoing task. In general, the results demonstrate that the different types of load affect prospective memory differentially.

  20. Heavy metals in our foodstuffs

    Energy Technology Data Exchange (ETDEWEB)

    1983-11-01

    The special group ''chemistry of food and forensic chemistry'' of the Association of German Analytical Chemists in Munich in 1983 issued a statement on that subject. The publication points out how heavy metals (examples: lead, cadmium and mercury) make their way into the foodstuffs, how many heavy metals are contained in our foodstuffs, which heavy metals are indispensable minerals and which aren't, and which heavy metals are ingested with food. It concludes by discussing how heavy metal contamination of our food can be prevented.

  1. Detecting heavy quarks

    International Nuclear Information System (INIS)

    Benenson, G.; Chau, L.L.; Ludlam, T.; Paige, F.E.; Platner, E.D.; Protopopescu, S.D.; Rehak, P.

    1983-01-01

    In this exercise we examine the performance of a detector specifically configured to tag heavy quark (HQ) jets through direct observations of D-meson decays with a high resolution vertex detector. To optimize the performance of such a detector, we assume the small diamond beam crossing configuration as described in the 1978 ISABELLE proposal, giving a luminosity of 10 32 cm -2 sec -1 . Because of the very large backgrounds from light quark (LQ) jets, most triggering schemes at this luminosity require high P/sub perpendicular to/ leptons and inevitably give missing neutrinos. If alternative triggering schemes could be found, then one can hope to find and calculate the mass of objects decaying to heavy quarks. A scheme using the high resolution detector will also be discussed in detail. The study was carried out with events generated by the ISAJET Monte Carlo and a computer simulation of the described detector system

  2. Heavy ion fusion III

    International Nuclear Information System (INIS)

    Hammer, D.; Max, C.; Perkins, F.; Rosenbluth, M.

    1987-03-01

    This report updates Heavy Ion Fusion, JSR-82-302, dated January, 1983. During the last four years, program management and direction has been changed and the overall Inertial Confinement Program has been reviewed. This report therefore concentrates on accelerator physics issues, how the program has addressed those issues during the last four years, and how it will be addressing them in the future. 8 refs., 3 figs

  3. Experimental heavy quarkonium physics

    International Nuclear Information System (INIS)

    Bugge, L.

    1986-08-01

    Following some brief arguments on why heavy quarkonium spectroscopy is an important field of particle physics, some points on experimental techniques are discussed. Parts of the basic quarkonium phenomenology, including discussions of various items related to potensial models, are then presented. An up-to-date presentation is given of the state-of-the-art of experimental charmonium and bottomonium spectroscopy below open flavour threshold, including the confrontation of experimental results to representative theoretical predictions

  4. Relativistic heavy ion reactions

    Energy Technology Data Exchange (ETDEWEB)

    Brink, D M

    1989-08-01

    The theory of quantum chromodynamics predicts that if nuclear matter is heated to a sufficiently high temperature then quarks might become deconfined and a quark-gluon plasma could be produced. One of the aims of relativistic heavy ion experiments is to search for this new state of matter. These lectures survey some of the new experimental results and give an introduction to the theories used to interpret them. 48 refs., 4 tabs., 11 figs.

  5. Carburetor for heavy oils

    Energy Technology Data Exchange (ETDEWEB)

    Gautreau, L

    1905-03-06

    This invention relates to a carburetor for heavy oils in which the combustion liquid circulates successively in two annular spaces at the top and bottom of the vaporizer heated by the gas from the outlet and returning from there, after having been conveniently heated, to the constant level by an appropriate tube; the constant level can be surrounded by an annular chamber in which circulates a part of the gas from the outlet.

  6. Relativistic heavy ion physics

    International Nuclear Information System (INIS)

    Hansen, O.

    1985-01-01

    In the fall of 1986 beams of heavy ions up to A ∼ 40 at total energies up to E ∼ 225 GeV/-nucleon will become available for experiments at CERN (60 and 225 GeV/nucleon) and at Brookhaven (15.5 GeV/nucleon). Are these energies interesting in relation to the ideas of creating quark deconfinement? An energy consideration of the planned experiments is presented, as well as a description of the experimental arrangement. (Auth.)

  7. Neutrinos: Heavy water detector

    International Nuclear Information System (INIS)

    Anon.

    1990-01-01

    The proponents of the Sudbury Neutrino Observatory (SNO) received a welcome Christmas present when William Winegard, Canadian Minister for Science and Technology announced the final details of the funding for this project, totalling 48 million Canadian dollars and including contributions from the US and the UK. The SNO experiment will extend significantly the study of solar neutrinos, using some 1,000 tonnes of heavy water to be installed more than two kilometres below ground in a nickel mine at Sudbury, Ontario

  8. Canadian heavy water production

    International Nuclear Information System (INIS)

    Dahlinger, A.; Lockerby, W.E.; Rae, H.K.

    1977-01-01

    The paper reviews Canadian experience in the production of heavy water, presents a long-term supply projection, relates this projection to the anticipated long-term electrical energy demand, and highlights principal areas for further improvement that form the bulk of the Canadian R and D programme on heavy water processes. Six Canadian heavy water plants with a total design capacity of 4000Mg/a are in operation or under construction. All use the Girdler-Sulphide (GS) process, which is based on deuterium exchange between water and hydrogen sulphide. Early operating problems have been overcome and the plants have demonstrated annual capacity factors in excess of 70%, with short-term production rates equal to design rates. Areas for further improvement are: to increase production rates by optimizing the control of foaming to give both higher sieve tray efficiency and higher flow rates, to reduce the incapacity due to deposition of pyrite (FeS 2 ) and sulphur (between 5% and 10%), and to improve process control and optimization of operating conditions by the application of mathematical simulations of the detailed deuterium profile throughout each plant. Other processes being studied, which look potentially attractive are the hydrogen-water exchange and the hydrogen-amine exchange. Even if they become successful competitors to the GS process, the latter is likely to remain the dominant production method for the next 10-20 years. This programme, when related to the long-term electricity demand, indicates that heavy water supply and demand are in reasonable balance and that the Candu programme will not be inhibited because of shortages of this commodity. (author)

  9. Relativistic heavy ion reactions

    International Nuclear Information System (INIS)

    Brink, D.M.

    1989-08-01

    The theory of quantum chromodynamics predicts that if nuclear matter is heated to a sufficiently high temperature then quarks might become deconfined and a quark-gluon plasma could be produced. One of the aims of relativistic heavy ion experiments is to search for this new state of matter. These lectures survey some of the new experimental results and give an introduction to the theories used to interpret them. 48 refs., 4 tabs., 11 figs

  10. Utah Heavy Oil Program

    Energy Technology Data Exchange (ETDEWEB)

    J. Bauman; S. Burian; M. Deo; E. Eddings; R. Gani; R. Goel; C.K. Huang; M. Hogue; R. Keiter; L. Li; J. Ruple; T. Ring; P. Rose; M. Skliar; P.J. Smith; J.P. Spinti; P. Tiwari; J. Wilkey; K. Uchitel

    2009-10-20

    The Utah Heavy Oil Program (UHOP) was established in June 2006 to provide multidisciplinary research support to federal and state constituents for addressing the wide-ranging issues surrounding the creation of an industry for unconventional oil production in the United States. Additionally, UHOP was to serve as an on-going source of unbiased information to the nation surrounding technical, economic, legal and environmental aspects of developing heavy oil, oil sands, and oil shale resources. UHOP fulGilled its role by completing three tasks. First, in response to the Energy Policy Act of 2005 Section 369(p), UHOP published an update report to the 1987 technical and economic assessment of domestic heavy oil resources that was prepared by the Interstate Oil and Gas Compact Commission. The UHOP report, entitled 'A Technical, Economic, and Legal Assessment of North American Heavy Oil, Oil Sands, and Oil Shale Resources' was published in electronic and hard copy form in October 2007. Second, UHOP developed of a comprehensive, publicly accessible online repository of unconventional oil resources in North America based on the DSpace software platform. An interactive map was also developed as a source of geospatial information and as a means to interact with the repository from a geospatial setting. All documents uploaded to the repository are fully searchable by author, title, and keywords. Third, UHOP sponsored Give research projects related to unconventional fuels development. Two projects looked at issues associated with oil shale production, including oil shale pyrolysis kinetics, resource heterogeneity, and reservoir simulation. One project evaluated in situ production from Utah oil sands. Another project focused on water availability and produced water treatments. The last project considered commercial oil shale leasing from a policy, environmental, and economic perspective.

  11. Outlook for Saskatchewan heavy oil

    International Nuclear Information System (INIS)

    Youzwa, P.

    1993-01-01

    Some of the opportunities and challenges currently facing the heavy oil industry in Saskatchewan are discussed from a government perspective. By the end of September 1993, 220 heavy oil wells were drilled in the province, and 26% of the land sales in 1993 were in heavy oil areas. About 41% of the wells drilled in heavy oil areas were horizontal oil wells. Of the total horizontal wells drilled in Saskatchewan, 48% are for heavy oil, and horizontal well production averages 85 bbl/d. Initial trends suggest that horizontal wells both accelerate production and contribute to ultimate recovery. Total heavy oil production in 1992 reached 28.9 million bbl and recoverable reserves in 1991 were 262.3 million bbl, or 1.5% of total oil in place. The low recovery is not only due to technical factors such as high viscosity but also to low investment in the heavy oil sector due to poor economics. It is hoped that lower interest and exchange rates, the success of horizontal wells and the provincial royalty structure will maintain the recent increase in heavy oil activity. The provincial government recently launched a comprehensive energy strategy in which development of a heavy oil strategy is an important component. Total heavy oil reserves exceed those of light and medium oil and have significant development potential. The Saskatchewan government wishes to adopt a cooperative and partnership approach in its dealings with the heavy oil industry to help realize this potential. 9 figs

  12. Hoists having load support in the event of hoist failure

    International Nuclear Information System (INIS)

    Webb, J.

    1984-01-01

    A hoist having lifting means for a very heavy load also has rotatable threaded rod load supporters depending from the hoist to which the load is coupled by nuts and arms. The supporters are rotated by a slipping drive so that the nuts try to move in advance of a rise or fall of the load. The advance drive applies a raising or lowering force to the supporters which are free to move axially within small tolerances. At the limit of the tolerances brakes are applied to the rotation of the supporters. In the event of the hoist releasing the load, the load becomes supported by the arms and nuts on the supporters with the supporters firmly braked. (author)

  13. Heavy ion transfer reactions

    International Nuclear Information System (INIS)

    Weisser, D.C.

    1977-06-01

    To complement discussions on the role of γ rays in heavy ion induced reactions, the author discusses the role played by particle detection. Transfer reactions are part of this subject and are among those in which one infers the properties of the residual nucleus in a reaction by observing the emerging light nucleus. Inelastic scattering ought not be excluded from this subject, although no particles are transferred, because of the role it plays in multistep reactions and in fixing O.M. parameters describing the entrance channel of the reaction. Heavy ion transfer reaction studies have been under study for some years and yet this research is still in its infancy. The experimental techniques are difficult and the demands on theory rigorous. One of the main products of heavy ion research has been the thrust to re-examine the assumptions of reaction theory and now include many effects neglected for light ion analysis. This research has spurred the addition of multistep processes to simple direct processes and coupled channel calculations. (J.R.)

  14. Heavy ion fusion

    International Nuclear Information System (INIS)

    Hofmann, Ingo

    1993-01-01

    With controlled thermonuclear fusion holding out the possibility of a prolific and clean new source of energy, the goal remains elusive after many years of continual effort. While the conventional Tokamak route with magnetic confinement continues to hit the headlines, other alternatives are now becoming competitive. One possible solution is to confine the thermonuclear fuel pellet by high power beams. Current research and perspectives for future work in such inertial confinement was the subject of the 'Prospects for Heavy Ion Fusion' European Research Conference held in Aghia Pelaghia, Crete, last year. Its main focus was on the potential of heavy ion accelerators as well as recent advances in target physics with high power lasers and light ion beams. Carlo Rubbia declared that high energy accelerators, with their high efficiency, are the most promising approach to economical fusion energy production. However the need for cost saving in the driver accelerator requires new ideas in target design tailored to the particularities of heavy ion beams, which need to be pushed to the limits of high current and phase space density at the same time

  15. Heavy flavor spectroscopy

    International Nuclear Information System (INIS)

    Rosen, J.; Marques, J.; Spiegel, L.

    1993-09-01

    As a useful by-product of the unfolding searches for mixing and CP-violation effects in the beauty sector there will accrue very large data samples for the study of heavy flavor spectroscopy. Interest in this field may be provisionally divided into two general classes: Hidden flavor states, i.e. c bar c and b bar b onium states; open flavor states: The D, D s , B, B s , and B c meson systems; and charm and beauty flavored baryons. In this brief note we emphasize that there are many missing states in both categories -- states which are not readily produced exclusively due to quantum number preferences or states which are not readily observed inclusively due to experimentally difficult decay channels. As recorded luminosities increase it may be possible to fill in some of the holes in the present listings of heavy flavor states. Of particular interest to us would be the identification of heavy flavor mesons which are not easily explained in terms of a q bar q paradigm but rather may be evidence for hadro-molecular states. At Snowmass 1993 the topic of self-tagging schemes in B meson production was very much in vogue. Whether or not excited B-meson flavor-tagging will prove to be competitive with traditional methods based on the partner bar B decay remains to be seen. We suggest however that the richness of the excited B-system may undermine the efficacy of self-tagging schemes

  16. Searching for heavy leptons

    International Nuclear Information System (INIS)

    Perl, M.L.

    1979-11-01

    This frankly speculative paper discusses ways in which leptons heavier than the tau (if they exist) might be found. The status of the tau is briefly reviewed, and methods for searching for sequential charged leptons beyond the tau and other charged leptons at PEP, PETRA, and CESR are sketched. Charged leptons with mass greater than 20 GeV/c 2 might be found at proton accelerators in hadron-hadron, photon-hadron, or ν-hadron collisions. Unstable, neutral heavy leptons might have unique, conserved lepton number or nonunique lepton number. The most difficult leptons to detect are stable neutral heavy leptons; nevertheless, a possible detection method is suggested. The obvious solution to seeking the postulated leptons is an e + e - colliding beam storage ring with c.m. energy = several hundred GeV. Until such a machine is built, one can employ Z 0 → L + + L - ; the use of R/sub Z 0 / and GAMMA/sub Z 0 / in this connection is discussed. If heavier Z 0 's exist, the heavy lepton search can be extended to higher energies. Another solution for producing these leptons involves the use of clashing e + e - linear accelerators. Characteristics of storage rings are compared with those of clashing linacs; a general description is given of the proposed SLAC Linac-Collider, along with the physics that could be done at such a machine. 6 figures

  17. Heavy flavor spectroscopy

    International Nuclear Information System (INIS)

    Rosen, J.; Marques, J.; Spiegel, L.

    1993-01-01

    As a useful by-product of the unfolding searches for mixing and CP-violation effects in the beauty sector there will accrue very large data samples for the study of heavy flavor spectroscopy. (I) Hidden flavor states, i.e. c bar c and b bar b onium states. (II) Open flavor states (a) the D, D s , B, B s , and B c meson systems; (b) Charm and beauty flavored baryons. In this brief note the authors emphasize that there are many missing (undiscovered) states in both categories - states which are not readily produced exclusively due to quantum number preferences or states which are not readily observed inclusively due to experimentally difficult decay channels. As recorded luminosities increase it may be possible to fill in some of the holes in the present listings of heavy flavor states. Of particular interest to the authors would be the identification of heavy flavor mesons which are not easily explained in terms of a q bar q paradigm but rather may be evidence for hadro-molecular status. At Snowmass 1993 the topic of self-tagging schemes in B meson production was very much in vogue. Whether or not excited B-meson flavor-tagging will prove to be competitive with traditional methods based on the partner B decay remains to be seen. The authors suggest however that the richness of the excited B-system may undetermine the efficacy of self-tagging schemes

  18. Heavy ion inertial fusion

    International Nuclear Information System (INIS)

    Fessenden, T.J.; Friedman, A.

    1991-01-01

    This report describes the research status in the following areas of research in the field of heavy ion inertial fusion: (1) RF accelerators, storage rings, and synchrotrons; (2) induction linacs; (3) recirculation induction accelerator approach; (4) a new accelerator concept, the ''Mirrortron''; (5) general issues of transport, including beam merging, production of short, fat quadrupoles with nearly linear focusing, calculations of beam behaviour in image fields; 3-D electrostatic codes on drift compression with misalignments and transport around bends; (6) injectors, ion sources and RFQs, a.o., on the development of a 27 MHz RFQ to be used for the low energy portion of a new injector for all ions up to Uranium, and the development of a 2 MV carbon ion injector to provide 16 C + beams of 0.5 A each for ILSE; (7) beam transport from accelerator to target, reporting, a.o., the feasibility to suppress third-order aberrations; while Particle-in-Cell simulations on the propagation of a non-neutral ion beam in a low density gas identified photo-ionization by thermal X-rays from the target as an important source of defocusing; (9) heavy ion target studies; (10) reviewing experience with laser drivers; (11) ion cluster stopping and muon catalyzed fusion; (12) heavy ion systems, including the option of a fusion-fission burner. 1 tab

  19. Analysis and Pollution Assessment of Heavy Metal in Soil, Perlis

    International Nuclear Information System (INIS)

    Siti Norbaya Mat Ripin; Siti Norbaya Mat Ripin; Sharizal Hasan; Mohd Lias Kamal; NorShahrizan Mohd Hashim

    2014-01-01

    Concentration of 5 heavy metals (Cu, Cr, Ni, Cd, Pb) were studied in the soils around Perlis, to assess heavy metals contamination distribution due to industrialization, urbanization and agricultural activities. Soil samples were collected at depth of 0-15 cm in eighteen station around Perlis. The soil samples (2 mm) were obtained duplicates and subjected to hot block digestion and the concentration of total metal was determined via ICP-MS. Overall concentrations of Cu, Cr, Ni, Cd and Pb in the soil samples ranged from 0.38-240.59, 0.642-3.921, 0.689-2.398, 0-0.63 and 0.39-27.47 mg/ kg respectively. The concentration of heavy metals in the soil display the following decreasing trend: Cu> Pb> Cr> Ni> Cd. From this result, found that level of heavy metal in soil near centralized Chuping industrial areas give maximum value compared with other location in Perlis. The Pollution index revealed that only 11 % of Cu and 6 % of Cd were classes as heavily contaminated. Meanwhile, Cu and Pb showed 6 % from all samples result a moderately contaminated and the others element give low contamination. Results of combined heavy metal concentration and heavy metal assessment indicate that industrial activities and traffic emission represent most important sources for Cu, Cd and Pb whereas Cr, Ni mainly from natural sources. Increasing anthropogenic influences on the environment, especially pollution loadings, have caused negative changes in natural ecosystems and decreased biodiversity. (author)

  20. Improving the Quality of Online Discussion: The Effects of Strategies Designed Based on Cognitive Load Theory Principles

    Science.gov (United States)

    Darabi, Aubteen; Jin, Li

    2013-01-01

    This article focuses on heavy cognitive load as the reason for the lack of quality associated with conventional online discussion. Using the principles of cognitive load theory, four online discussion strategies were designed specifically aiming at reducing the discussants' cognitive load and thus enhancing the quality of their online discussion.…

  1. APS high heat load monochromator

    International Nuclear Information System (INIS)

    Lee, W.K.; Mills, D.

    1993-02-01

    This document contains the design specifications of the APS high heat load (HHL) monochromator and associated accessories as of February 1993. It should be noted that work is continuing on many parts of the monochromator including the mechanical design, crystal cooling designs, etc. Where appropriate, we have tried to add supporting documentation, references to published papers, and calculations from which we based our decisions. The underlying philosophy behind performance specifications of this monochromator was to fabricate a device that would be useful to as many APS users as possible, that is, the design should be as generic as possible. In other words, we believe that this design will be capable of operating on both bending magnet and ID beamlines (with the appropriate changes to the cooling and crystals) with both flat and inclined crystal geometries and with a variety of coolants. It was strongly felt that this monochromator should have good energy scanning capabilities over the classical energy range of about 4 to 20 keywith Si (111) crystals. For this reason, a design incorporating one rotation stage to drive both the first and second crystals was considered most promising. Separate rotary stages for the first and second crystals can sometimes provide more flexibility in their capacities to carry heavy loads (for heavily cooled first crystals or sagittal benders of second crystals), but their tuning capabilities were considered inferior to the single axis approach

  2. Wind Loads on Structures

    DEFF Research Database (Denmark)

    Dyrbye, Claes; Hansen, Svend Ole

    Wind loads have to be taken into account when designing civil engineering structures. The wind load on structures can be systematised by means of the wind load chain: wind climate (global), terrain (wind at low height), aerodynamic response (wind load to pressure), mechanical response (wind...... pressure to structural response) and design criteria. Starting with an introduction of the wind load chain, the book moves on to meteorological considerations, atmospheric boundary layer, static wind load, dynamic wind load and scaling laws used in wind-tunnel tests. The dynamic wind load covers vibrations...... induced by wind turbulence, vortex shedding, flutter and galloping. The book gives a comprehensive treatment of wind effects on structures and it will be useful for consulting engineers designing wind-sensitive structures. It will also be valuable for students of civil engineering as textbook...

  3. Carbohydrate-Loading Diet

    Science.gov (United States)

    ... Grape juice (12 ounces) 55 225 Lunch Milk, chocolate, reduced fat (12 ounces) 45 285 4 slices ... usual during carbohydrate loading to get the same benefits as a man does. Despite carbohydrate loading, you ...

  4. Autonomous Propellant Loading Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The AES Autonomous Propellant Loading (APL) project consists of three activities. The first is to develop software that will automatically control loading of...

  5. Fuel pellet loading apparatus

    International Nuclear Information System (INIS)

    1980-01-01

    Apparatus is described for loading a predetermined amount of nuclear fuel pellets into nuclear fuel elements and particularly for the automatic loading of fuel pellets from within a sealed compartment. (author)

  6. Heavy-heavy and heavy-light quarks interactions generated by QCD vacuum

    Directory of Open Access Journals (Sweden)

    Musakhanov Mirzayusuf

    2017-01-01

    Full Text Available The QCD vacuum is populated by instantons that correspond to the tunneling processes in the vacuum. This mechanism creates the strong vacuum gluon fields. As result, the QCD vacuum instantons induce very strong interactions between light quarks, initially almost massless. Such a strong interactions bring a large dynamical mass M of the light quarks and bound them to produce almost massless pions in accordance with the spontaneous breaking of the chiral symmetry (SBCS. On the other hand, the QCD vacuum instantons also interact with heavy quarks and responsible for the generation of the heavy-heavy and heavy-light quarks interactions, with a traces of the SBCS. If we take the average instanton size ρ¯=0.33$\\bar \\rho = 0.33$ fm, and the average inter-instanton distance R¯=1$\\bar R = 1$ fm we obtain the dynamical light quark mass to be M = 365 MeV and the instanton media contribution to the heavy quark mass ΔM=70 MeV. These factors define the coupling between heavy-light and heavy-heavy quarks induced by the QCD vacuum instantons. We consider first the instanton effects on the heavy-heavy quarks potential, including its spin-dependent part. We also discuss those effects on the masses of the charmonia and their hyperfine mass splittings. At the second part we discuss the interaction between a heavy and light quarks generated by instantons and it’s effects.

  7. Limit loads in nozzles

    International Nuclear Information System (INIS)

    Zouain, N.

    1983-01-01

    The static method for the evaluation of the limit loads of a perfectly elasto-plastic structure is presented. Using the static theorem of Limit Analysis and the Finite Element Method, a lower bound for the colapso load can be obtained through a linear programming problem. This formulation if then applied to symmetrically loaded shells of revolution and some numerical results of limit loads in nozzles are also presented. (Author) [pt

  8. The estimation of heavy metal concentration in FBR reprocessing solvent streams by density measurement

    International Nuclear Information System (INIS)

    Brown, M.L.; Savage, D.J.

    1986-04-01

    The application of density measurement to heavy metal monitoring in the solvent phase is described, including practical experience gained during three fast reactor fuel reprocessing campaigns. An experimental algorithm relating heavy metal concentration and sample density was generated from laboratory-measured density data, for uranyl nitrate dissolved in nitric acid loaded tri-butyl phosphate in odourless kerosene. Differences in odourless kerosene batch densities are mathematically interpolated, and the algorithm can be used to estimate heavy metal concentrations from the density to within +1.5 g/l. An Anton Paar calculating digital densimeter with remote cell operation was used for all density measurements, but the algorithm will give similar accuracy with any density measuring device capable of a precision of better than 0.0005 g/cm 3 . For plant control purposes, the algorithm was simplified using a density referencing system, whereby the density of solvent not yet loaded with heavy metal is subtracted from the sample density. This simplified algorithm compares very favourably with empirical algorithms, derived from numerical analysis of density data and chemically measured uranium and plutonium data obtained during fuel reprocessing campaigns, particularly when differences in the acidity of the solvent are considered before and after loading with heavy metal. This simplified algorithm had been successfully used for plant control of heavy metal loaded solvent during four fast reactor fuel reprocessing campaigns. (author)

  9. Modelling heavy metals build-up on urban road surfaces for effective stormwater reuse strategy implementation

    International Nuclear Information System (INIS)

    Hong, Nian; Zhu, Panfeng; Liu, An

    2017-01-01

    Urban road stormwater is an alternative water resource to mitigate water shortage issues in the worldwide. Heavy metals deposited (build-up) on urban road surface can enter road stormwater runoff, undermining stormwater reuse safety. As heavy metal build-up loads perform high variabilities in terms of spatial distribution and is strongly influenced by surrounding land uses, it is essential to develop an approach to identify hot-spots where stormwater runoff could include high heavy metal concentrations and hence cannot be reused if it is not properly treated. This study developed a robust modelling approach to estimating heavy metal build-up loads on urban roads using land use fractions (representing percentages of land uses within a given area) by an artificial neural network (ANN) model technique. Based on the modelling results, a series of heavy metal load spatial distribution maps and a comprehensive ecological risk map were generated. These maps provided a visualization platform to identify priority areas where the stormwater can be safely reused. Additionally, these maps can be utilized as an urban land use planning tool in the context of effective stormwater reuse strategy implementation. - Highlights: • A model was developed to simulate heavy metal build-up loads on urban roads. • This model is based on artificial neural networks. • Land use fractions was used to model build-up loads on different particle sizes. • The maps of heavy metal spatial distribution and ecological risk were generated. • This model can be used for effective stormwater reuse strategy implementation. - Development of a robust modelling approach to mapping heavy metals build-up and their ecological risks for stormwater reuse safety.

  10. Determination of heavy water in heavy water - light water mixtures

    International Nuclear Information System (INIS)

    Sanhueza M, A.

    1986-01-01

    A description about experimental methodology to determine isotopic composition of heavy water - light water mixtures is presented. The employed methods are Nuclear Magnetic Resonance Spectroscopy, for measuring heavy water concentrations from 0 to 100% with intervals of 10% approx., and mass Spectrometry, for measuring heavy water concentrations from 0.1 to 1% with intervals of 0.15% approx., by means of an indirect method of Dilution. (Author)

  11. The reliability of the Extra Load Index as a measure of relative load carriage economy.

    Science.gov (United States)

    Hudson, Sean; Cooke, Carlton; Lloyd, Ray

    2017-09-01

    The aim of this study was to measure the reliability of the extra load index (ELI) as a method for assessing relative load carriage economy. Seventeen volunteers (12 males, 5 females) performed walking trials at 3 km·h -1 , 6 km·h -1 and a self-selected speed. Trial conditions were repeated 7 days later to assess test-retest reliability. Trials involved four 4-minute periods of walking, each separated by 5 min of rest. The initial stage was performed unloaded followed in a randomised order by a second unloaded period and walking with backpacks of 7 and 20 kg. Results show ELI values did not differ significantly between trials for any of the speeds (p = 0.46) with either of the additional loads (p = 0.297). The systematic bias, limits of agreement and coefficients of variation were small in all trial conditions. We conclude the ELI appears to be a reliable measure of relative load carriage economy. Practitioner Summary: This paper demonstrates that the ELI is a reliable measure of load carriage economy at a range of walking speeds with both a light and heavy load. The ELI, therefore, represents a useful tool for comparing the relative economy associated with different load carriage systems.

  12. Heavy water upgrading system in the Fugen heavy water reactor

    International Nuclear Information System (INIS)

    Matsushita, T.; Susaki, S.

    1980-01-01

    The heavy water upgrading system, which is installed in the Fugen heavy water reactor (HWR) was designed to reuse degraded heavy water generated from the deuteration-dedeuteration of resin in the ion exchange column of the moderator purification system. The electrolysis method has been applied in this system on the basis of the predicted generation rate and concentration of degraded heavy water. The structural feature of the electrolytic cell is that it consists of dual cylindrical electrodes, instead of a diaphragm as in the case of conventional water electrolysis. 2 refs

  13. Heavy Truck Engine Program

    Energy Technology Data Exchange (ETDEWEB)

    Nelson, Christopher

    2009-01-08

    The Heavy Duty Truck Engine Program at Cummins embodied three significant development phases. All phases of work strove to demonstrate a high level of diesel engine efficiency in the face of increasingly stringent emission requirements. Concurrently, aftertreatment system development and refinement was pursued in support of these efficiency demonstrations. The program's first phase focused on the demonstration in-vehicle of a high level of heavy duty diesel engine efficiency (45% Brake Thermal Efficiency) at a typical cruise condition while achieving composite emissions results which met the 2004 U.S. EPA legislated standards. With a combination of engine combustion calibration tuning and the development and application of Urea-based SCR and particulate aftertreatment, these demonstrations were successfully performed by Q4 of 2002. The second phase of the program directed efforts towards an in-vehicle demonstration of an engine system capable of meeting 2007 U.S. EPA legislated emissions requirements while achieving 45% Brake Thermal Efficiency at cruise conditions. Through further combustion optimization, the refinement of Cummins Cooled EGR architecture, the application of a high pressure common rail fuel system and the incorporation of optimized engine parasitics, Cummins Inc. successfully demonstrated these deliverables in Q2 of 2004. The program's final phase set a stretch goal of demonstrating 50% Brake Thermal Efficiency from a heavy duty diesel engine system capable of meeting 2010 U.S. EPA legislated emissions requirements. Cummins chose to pursue this goal through further combustion development and refinement of the Cooled EGR system architecture and also applied a Rankine cycle Waste Heat Recovery technique to convert otherwise wasted thermal energy to useful power. The engine and heat recovery system was demonstrated to achieve 50% Brake Thermal Efficiency while operating at a torque peak condition in second quarter, 2006. The 50% efficient

  14. Heavy Haul Access to U.S. Ports.

    Science.gov (United States)

    2017-10-01

    Texas exporters are increasingly concerned that current overweight regulations do not allow for the full use of the capacity of oceangoing containers. Even with an over-axle/over-gross weight tolerance permit (also known as the HB 2060 permit), the o...

  15. Spatial electric load forecasting

    CERN Document Server

    Willis, H Lee

    2002-01-01

    Spatial Electric Load Forecasting Consumer Demand for Power and ReliabilityCoincidence and Load BehaviorLoad Curve and End-Use ModelingWeather and Electric LoadWeather Design Criteria and Forecast NormalizationSpatial Load Growth BehaviorSpatial Forecast Accuracy and Error MeasuresTrending MethodsSimulation Method: Basic ConceptsA Detailed Look at the Simulation MethodBasics of Computerized SimulationAnalytical Building Blocks for Spatial SimulationAdvanced Elements of Computerized SimulationHybrid Trending-Simulation MethodsAdvanced

  16. Cognitive Load and Cooperation

    DEFF Research Database (Denmark)

    Døssing, Felix Sebastian; Piovesan, Marco; Wengström, Erik Roland

    2017-01-01

    We study the effect of intuitive and reflective processes on cooperation using cognitive load. Compared with time constraint, which has been used in the previous literature, cognitive load is a more direct way to block reflective processes, and thus a more suitable way to study the link between...... intuition and cooperation. Using a repeated public goods game, we study the effect of different levels of cognitive load on contributions. We show that a higher cognitive load increases the initial level of cooperation. In particular, subjects are significantly less likely to fully free ride under high...... cognitive load....

  17. Heavy fragment radioactivity

    International Nuclear Information System (INIS)

    Silisteanu, I.

    1991-06-01

    The effect of collective mode excitation in heavy fragment radioactivity (HFR) is explored and discussed in the light of current experimental data. It is found that the coupling and resonance effects in fragment interaction and also the proper angular momentum effects may lead to an important enhancing of the emission process. New useful procedures are proposed for the study of nuclear decay properties. The relations between different decay processes are investigated in detail. We are also trying to understand and explain in a unified way the reaction mechanisms in decay phenomena. (author). 17 refs, 4 figs, 3 tabs

  18. Fission of heavy hypernuclei

    International Nuclear Information System (INIS)

    Nifenecker, H.

    1993-01-01

    The results on delayed and prompt fission of heavy hypernuclei obtained by the LEAR PS177 collaboration are recalled and discussed. It is shown that the hypernuclei life-times can be explained in term of a weak strangeness violating lambda-nucleon interaction with a cross section close to 6.0 10 -15 barns. The lambda attachment function is shown to be sensitive to the scission configuration, just before fission, and to the neck dynamics. This function provides a new way to study the nuclear scission process. (author)

  19. Heavy gas valves

    Energy Technology Data Exchange (ETDEWEB)

    Steier, L [Vereinigte Armaturen Gesellschaft m.b.H., Mannheim (Germany, F.R.)

    1979-01-01

    Heavy gas valves must comply with special requirements. Apart from absolute safety in operation there are stringent requirements for material, sealing and ease of operation even in the most difficult conditions. Ball valves and single plate pipe gate valves lateral sealing rings have a dual, double sided sealing effect according to the GROVE sealing system. Single plate gate valves with lateral protective plates are suitable preferably for highly contaminated media. Soft sealing gate valves made of cast iron are used for low pressure applications.

  20. Relativistic heavy ion collisions

    International Nuclear Information System (INIS)

    Barz, H.W.; Kaempfer, B.; Schulz, H.

    1984-12-01

    An elementary introduction is given into the scenario of relativistic heavy ion collisions. It deals with relativistic kinematics and estimates of energy densities, extrapolations of the present knowledge of hadron-hadron and hadron-nuleus to nucleus-nucleus collisions, the properties of the quark-gluon plasma and the formation of the plasma and possible experimental signatures. Comments are made on a cosmic ray experiment which could be interpreted as a first indication of the quark-gluon phase of the matter. (author)

  1. Heavy Quarkonium Physics

    CERN Document Server

    CERN. Geneva; Krämer, Michael; Mussa, Roberto; Vairo, Antonio; Bali, G S; Bodwin, G T; Braaten, E; Eichten, E; Eidelman, S; Godfrey, S; Hoang, A; Jamin, M; Kharzeev, Dima E; Lombardo, M P; Lourenço, C; Meyer, A B; Papadimitriou, V; Patrignani, C; Rosati, M; Sanchis-Lozano, M A; Satz, Helmut; Soto, J; Besson, D Z; Bettoni, D; Böhrer, A; Boogert, S; Chang, C H; Cooper, P; Crochet, Philippe; Datta, S; Davies, C; Deandrea, A; Faustov, R; Ferguson, T; Galik, R; Harris, F; Iouchtchenko, O; Kaczmarek, O; Karsch, Frithjof; Kienzle, M; Kiselev, V V; Klein, S R; Kroll, P; Kronfeld, A S; Kuang Yu Ping; Laporta, V; Lee, J; Leibovich, A K; Ma, J P; MacKenzie, P; Maiani, Luciano; Mangano, Michelangelo L; Meyer, A; Mo, X H; Morningstar, C; Nairz, A; Napolitano, J; Olsen, S; Penin, A A; Petreczky, P; Piccinini, F; Pineda, A; Polosa, Antonio; Ramello, L; Rapp, R; Richard, J M; Riquer, V; Ricciardi, S; Robutti, E; Schneider, O; Scomparin, E; Simone, J; Skwarnicki, T; Stancari, G; Stewart, I W; Sumino, Y; Teubner, T; Tseng, J; Vogt, R; Wang, P; Yabsley, B D; Yuan, C Z; Zantow, F; Zhao, Z G; Zieminski, A

    2005-01-01

    This report is the result of the collaboration and research effort of the Quarkonium Working Group over the last three years. It provides a comprehensive overview of the state of the art in heavy-quarkonium theory and experiment, covering quarkonium spectroscopy, decay, and production, the determination of QCD parameters from quarkonium observables, quarkonia in media, and the effects on quarkonia of physics beyond the Standard Model. An introduction to common theoretical and experimental tools is included. Future opportunities for research in quarkonium physics are also discussed.

  2. Heavy transport problems

    International Nuclear Information System (INIS)

    Haas, K.F.

    1975-01-01

    Assuming that very often a long transport route from the factory of the manufacturer to the provided site has to be reckoned with, in general only transport with a ship is possible. As each site is only called by a certain steamship line, at a very early stage of planning the nuclear power plant the possibilities and capacities of the lines and means of transportation under discussion should be investigated. In planning the unloading equipment at the site, due consideration should be given to the fact that at a later time this equipment should also be suitable for the transport of heavy components and spent fuel assemblies. (orig.) [de

  3. Heavy Quark Effective Theory

    Science.gov (United States)

    Manohar, A. V.

    2003-02-01

    These lecture notes present some of the basic ideas of heavy quark effective theory. The topics covered include the classification of states, the derivation of the HQET Lagrangian at tree level, hadron masses, meson form factors, Luke's theorem, reparameterization invariance and inclusive decays. Radiative corrections are discussed in some detail, including an explicit computation of a matching correction for HQET. Borel summability, renormalons, and their connection with the QCD perturbation series is covered, as well as the use of the upsilon expansion to improve the convergence of the perturbation series.

  4. Heavy ion storage rings

    International Nuclear Information System (INIS)

    Schuch, R.

    1987-01-01

    A brief overview of synchrotron storage rings for heavy ions, which are presently under construction in different accelerator laboratories is given. Ions ranging from protons up to uranium ions at MeV/nucleon energies will be injected into these rings using multiturn injection from the accelerators available or being built in these laboratories. After injection, it is planned to cool the phase space distribution of the ions by merging them with cold electron beams or laser beams, or by using stochastic cooling. Some atomic physics experiments planned for these rings are presented. 35 refs

  5. [Relativistic heavy ion research

    International Nuclear Information System (INIS)

    1991-01-01

    The present document describes our second-year application for a continuation grant on relativistic heavy-ion research at Nevis Laboratories, Columbia University, over the two-year period starting from November 15, 1990. The progress during the current budget year is presented. This year, construction of RHIC officially began. As a result, the entire Nevis nuclear physics group has made a coherent effort to create new proposal for an Open Axially Symmetric Ion Spectrometer (OASIS) proposal. Future perspectives and our plans for this proposal are described

  6. Characterization of heavy metal desorption from road-deposited sediment under acid rain scenarios.

    Science.gov (United States)

    Zhao, Bo; Liu, An; Wu, Guangxue; Li, Dunzhu; Guan, Yuntao

    2017-01-01

    Road-deposited sediments (RDS) on urban impervious surfaces are important carriers of heavy metals. Dissolved heavy metals that come from RDS influenced by acid rain, are more harmful to urban receiving water than particulate parts. RDS and its associated heavy metals were investigated at typical functional areas, including industrial, commercial and residential sites, in Guangdong, Southern China, which was an acid rain sensitive area. Total and dissolved heavy metals in five particle size fractions were analyzed using a shaking method under acid rain scenarios. Investigated heavy metals showed no difference in the proportion of dissolved fraction in the solution under different acid rain pHs above 3.0, regardless of land use. Dissolved loading of heavy metals related to organic carbon content were different in runoff from main traffic roads of three land use types. Coarse particles (>150μm) that could be efficiently removed by conventional street sweepers, accounted for 55.1%-47.1% of the total dissolved metal loading in runoff with pH3.0-5.6. The obtained findings provided a significant scientific basis to understand heavy metal release and influence of RDS grain-size distribution and land use in dissolved heavy metal pollution affected by acid rain. Copyright © 2016. Published by Elsevier B.V.

  7. Heavy ion therapy: Bevalac epoch

    International Nuclear Information System (INIS)

    Castro, J.R.

    1993-10-01

    An overview of heavy ion therapy at the Bevelac complex (SuperHILac linear accelerator + Bevatron) is given. Treatment planning, clinical results with helium ions on the skull base and uveal melanoma, clinical results with high-LET charged particles, neon radiotherapy of prostate cancer, heavy charged particle irradiation for unfavorable soft tissue sarcoma, preliminary results in heavy charged particle irradiation of bone sarcoma, and irradiation of bile duct carcinoma with charged particles and-or photons are all covered

  8. Spectroscopy of doubly heavy baryons

    International Nuclear Information System (INIS)

    Gershtein, S.S.; Kiselev, V.V.; Likhoded, A.K.; Onishchenko, A.I.

    2000-01-01

    Within a nonrelativistic quark model featuring a QCD-motivated Buchmueller-Tye potential, the mass spectra for the families of doubly heavy baryons are calculated by assuming the quark-diquark structure of the baryon wave functions and by taking into account spin-dependent splitting. Physically motivated evidence that, in the case where heavy quarks have identical flavors, quasistationary excited states may be formed in the heavy-diquark subsystem is analyzed

  9. Relativistic heavy-ion physics

    CERN Document Server

    Herrera Corral, G

    2010-01-01

    The study of relativistic heavy-ion collisions is an important part of the LHC research programme at CERN. This emerging field of research focuses on the study of matter under extreme conditions of temperature, density, and pressure. Here we present an introduction to the general aspects of relativistic heavy-ion physics. Afterwards we give an overview of the accelerator facility at CERN and then a quick look at the ALICE project as a dedicated experiment for heavy-ion collisions.

  10. Heavy quark production and spectroscopy

    International Nuclear Information System (INIS)

    Appel, J.A.

    1993-11-01

    This review covers many new experimental results on heavy flavor production and spectroscopy. It also shows some of the increasingly improved theoretical understanding of results in light of basic perturbative QCD and heavy quark symmetry. At the same time, there are some remaining discrepancies among experiments as well as significant missing information on some of the anticipated lowest lying heavy quark states. Most interesting, perhaps, are some clearly measured production effects awaiting full explanation

  11. Heavy quark spectroscopy

    International Nuclear Information System (INIS)

    Rosner, J.L.

    1985-10-01

    New experimental and theoretical developments in heavy quark spectroscopy are reviewed. From studies of J/psi decays, the eta' is found to have some ''glue'' or other inert component, while the iota (a glueball candidate) probably contains some quarks as well. The xi(2.2) persists in new Mark III data, but is not seen by the DM2 collaboration. The production of charmonium states by anti pp reactions is reviewed. First evidence for a P- wave charmed meson, D(2420), has been presented by the ARGUS group. Radiative UPSILON decay studies fail to confirm the zeta(8.3) and begin to place useful limits on Higgs bosons. First results from an experiment at Fermilab on low-background hadronic production of UPSILON states are shown. Accurate measurements of chi/sub b/(1P) masses by the ARGUS collaboration are noted, and interpreted as favoring scalar quark confinement. Studies of t and other heavy quarks will probe the q anti q interaction below 0.05 fm, are likely to be strongly affected by t anti t-Z interference, and can provide varied information on Higgs bosons. 144 refs., 21 figs

  12. Relativistic heavy ion physics

    International Nuclear Information System (INIS)

    Hill, J.C.; Wohn, F.K.

    1992-01-01

    In 1992 a proposal by the Iowa State University experimental nuclear physics group entitled ''Relativistic Heavy Ion Physics'' was funded by the US Department of Energy, Office of Energy Research, for a three-year period beginning November 15, 1991. This is a progress report for the first six months of that period but, in order to give a wider perspective, we report here on progress made since the beginning of calendar year 1991. In the first section, entitled ''Purpose and Trends,'' we give some background on the recent trends in our research program and its evolution from an emphasis on nuclear structure physics to its present emphasis on relativistic heavy ion and RHIC physics. The next section, entitled, ''Physics Research Programs,'' is divided into three parts. First, we discuss our participation in the program to develop a large detector named PHENIX for the RHIC accelerator. Second, we outline progress made in the study of electromagnetic dissociation (ED). A highlight of this endeavor is experiments carried out with the 197 Au beam from the AGS accelerator in April 1991. Third, we discuss progress in completion of our nuclear structure studies. In the final section a list of publications, invited talks and contributed talks starting in 1991 is given

  13. Actinides and heavy fermions

    International Nuclear Information System (INIS)

    Smith, J.L.; Fisk, Z.; Ott, H.R.

    1987-01-01

    The actinide series of elements begins with f-shell electrons forming energy bands, contributing to the bonding, and possessing no magnetic moments. At americium the series switches over to localized f electrons with magnetic moments. In metallic compounds this crossover of behavior can be modified and studied. In this continuum of behavior a few compounds on the very edge of localized f-electron behavior exhibit enormous electronic heat capacities at low temperatures. This is associated with an enhanced thermal mass of the conduction electrons, which is well over a hundred times the free electron mass, and is what led to the label heavy fermion for such compounds. A few of these become superconducting at even lower temperatures. The excitement in this field comes from attempting to understand how this heaviness arises and from the likelihood that the superconductivity is different from that of previously known superconductors. The effects of thorium impurities in UBe 13 were studied as a representative system for studying the nature of the superconductivity

  14. Heavy ion fusion

    International Nuclear Information System (INIS)

    Bock, R.

    1983-01-01

    Two accelerator scenarios for heavy ion fusion are considered as driver candidates for an ICF power plant: the RF linac with storage rings and the induction linac. The necessary beam intensity and beam quality requirements are already believed to be achievable in the long run; repetition rate and accelerator efficiency are not critical issues. Conceptual design studies have indicated that the technical problems of the ICF concept with a heavy ion driver can be solved and that the economical aspects are not prohibitive as compared to other ICF concepts. Nevertheless, many open problems still exist, and some new ones have exhibited themselves, and it has become evident that most of them cannot be investigated with existing facilities and at the present level of effort. The first section of this paper deals with current conceptual design studies and focuses on the interface between the accelerator and the reactor. The second section summarizes the present research programs and recommends that their scope should be expanded and intensified in the areas of accelerator physics and beam-target interaction and target physics. In the third section the author calls for a dedicated facility and reports on the plans and ideas for such a facility. Schematics of two proposed accelerator driver systems--the driver for HIBALL (5 MJ/pulse) and a single-pass four-beam induction linac (3 MJ/pulse)--are provided

  15. Heavy ion accelerating structure

    International Nuclear Information System (INIS)

    Pottier, Jacques.

    1977-01-01

    The heavy ion accelerating structure concerned in this invention is of the kind that have a resonance cavity inside which are located at least two longitudinal conducting supports electrically connected to the cavity by one of their ends in such a way that they are in quarter-wavelength resonance and in phase opposition. Slide tubes are electrically connected alternatively to one or the other of the two supports, they being electrically connected respectively to one or the other end of the side wall of the cavity. The feature of the structure is that it includes two pairs of supports symmetrically placed with respect to the centre line of the cavity, the supports of one pair fitted overhanging being placed symmetrically with respect to the centre line of the cavity, each slide tube being connected to the two supports of one pair. These support are connected to the slide wall of the cavity by an insulator located at their electrically free end. The accelerator structure composed of several structures placed end to end, the last one of which is fed by a high frequency field of adjustable amplitude and phase, enables a heavy ion linear accelerator to be built [fr

  16. Ultrarelativistic heavy ions

    International Nuclear Information System (INIS)

    Pugh, H.G.

    1980-12-01

    Studies with ultrarelativistic heavy ions combine aspects of cosmic ray physics, particle physics, nuclear physics, astrophysics and cosmogenesis. The leading theoretical concerns are the behavior of matter at very high-energy density and flux, the general behavior of space time in collisions, relativistic nuclear theory, and quantum chromodynamics. The field has developed over a period of more than thirty years, since the first observation of heavy nuclei in cosmic rays and the major developments of understanding of high-energy collisions made by Fermi and Landau in the early fifties. In the late sixties the discovery of the parton content of nucleons was rapidly followed by a great extension of high-energy collision phenomenology at the CERN ISR and subsequent confirmation of the QCD theory. In parallel the study of p-nucleus and nucleus-nucleus collisions at very high energies, especially at the CERN PS, Fermilab and the Bevalac, and in cosmic rays demonstrated that studies involving the nucleus opened up a new dimension in studies of the hadronic interaction. It is now at a high level of interest on an international scale, with major new accelerators being proposed to dedicate to this kind of study

  17. Methods of qualifying electrical cabinets for the load case earthquake

    International Nuclear Information System (INIS)

    Henkel, F.-O.; Kennerknecht, H.; Haefeli, T.; Jorgensen, F.

    2005-01-01

    With the qualification of electrical system cabinets for the load case earthquake it is differentiated between the two objectives: a) stability of the cabinet, and b) functionality of the built-in electrical modules during and after the earthquake. There are three methods to attain these goals: analyses, tests and proof by analogy. A common method is the shaking of a complete cabinet on a shaking table, with the advantage that stability and functionality can be proved at the same time, but with the disadvantage that quite expensive test equipment, especially a multi-axle shaking table, is necessary and that generally a cabinet which was proved for SSE is pre-affected and thus may not be incorporated into the plant offhand, i.e. the extreme example would be that the cabinet must be built twice. As a rule, analyses are currently carried out by means of Finite-Element-Models of the supporting structure with consideration of the electrical components at least with their masses. This analysis can prove the stability and pursue the excitation until the anchoring point of the electrical components (Henkel et al., 1987). The combination of the aforementioned two methods often constitutes the best way. The stability of the cabinet is proved by calculations, the functionality of the safety-relevant modules by tests. Once tested, modules identical in construction can be used for cabinets without further testing for earthquakes of similar or lower levels. Proof by analogy is possible only if tests or analyses of similar cabinets were done in advance. By means of the comparison of supporting structure, mass allocation and distribution, level and shape of the earthquake excitation it can be shown that the cabinet planned is covered by cabinets already tested or analysed (Katona et al., 1995). All facets of the various methods with advantages and disadvantages are discussed and explained on the basis of numerous examples. (authors)

  18. Analysis of heavy metals in road-deposited sediments.

    Science.gov (United States)

    Herngren, Lars; Goonetilleke, Ashantha; Ayoko, Godwin A

    2006-07-07

    Road-deposited sediments were analysed for heavy metal concentrations at three different landuses (residential, industrial, commercial) in Queensland State, Australia. The sediments were collected using a domestic vacuum cleaner which was proven to be highly efficient in collecting sub-micron particles. Five particle sizes were analysed separately for eight heavy metal elements (Zn, Fe, Pb, Cd, Cu, Cr, Al and Mn). At all sites, the maximum concentration of the heavy metals occurred in the 0.45-75 microm particle size range, which conventional street cleaning services do not remove efficiently. Multicriteria decision making methods (MCDM), PROMETHEE and GAIA, were employed in the data analysis. PROMETHEE, a non-parametric ranking analysis procedure, was used to rank the metal contents of the sediments sampled at each site. The most polluted site and particle size range were the industrial site and the 0.45-75 microm range, respectively. Although the industrial site displayed the highest metal concentrations, the highest heavy metal loading coincided with the highest sediment load, which occurred at the commercial site. GAIA, a special form of principal component analysis, was applied to determine correlations between the heavy metals and particle size ranges and also to assess possible correlation with total organic carbon (TOC). The GAIA-planes revealed that irrespective of the site, most of the heavy metals are adsorbed to sediments below 150 microm. A weak correlation was found between Zn, Mn and TOC at the commercial site. This could lead to higher bioavailability of these metals through complexation reactions with the organic species in the sediments.

  19. Substantiation of the road toll for heavy transport vehicles

    OpenAIRE

    Burmaka, N.; Chernykh, A.

    2010-01-01

    The existing and possible additional sources of developing state and local road funds of Ukraine have been considered. The formula for calculating monthly road toll for heavy transport vehicles has been proposed. This formula includes the payment rate per every kilometer of distance, the vehicle capacity utilization factor and the run with the load. The payment rate per every kilometer of distance for transport vehicles depending on the allowed total weight has been substantiated. The given r...

  20. Optimisation of load control

    International Nuclear Information System (INIS)

    Koponen, P.

    1998-01-01

    Electricity cannot be stored in large quantities. That is why the electricity supply and consumption are always almost equal in large power supply systems. If this balance were disturbed beyond stability, the system or a part of it would collapse until a new stable equilibrium is reached. The balance between supply and consumption is mainly maintained by controlling the power production, but also the electricity consumption or, in other words, the load is controlled. Controlling the load of the power supply system is important, if easily controllable power production capacity is limited. Temporary shortage of capacity causes high peaks in the energy price in the electricity market. Load control either reduces the electricity consumption during peak consumption and peak price or moves electricity consumption to some other time. The project Optimisation of Load Control is a part of the EDISON research program for distribution automation. The following areas were studied: Optimization of space heating and ventilation, when electricity price is time variable, load control model in power purchase optimization, optimization of direct load control sequences, interaction between load control optimization and power purchase optimization, literature on load control, optimization methods and field tests and response models of direct load control and the effects of the electricity market deregulation on load control. An overview of the main results is given in this chapter

  1. Optimisation of load control

    Energy Technology Data Exchange (ETDEWEB)

    Koponen, P [VTT Energy, Espoo (Finland)

    1998-08-01

    Electricity cannot be stored in large quantities. That is why the electricity supply and consumption are always almost equal in large power supply systems. If this balance were disturbed beyond stability, the system or a part of it would collapse until a new stable equilibrium is reached. The balance between supply and consumption is mainly maintained by controlling the power production, but also the electricity consumption or, in other words, the load is controlled. Controlling the load of the power supply system is important, if easily controllable power production capacity is limited. Temporary shortage of capacity causes high peaks in the energy price in the electricity market. Load control either reduces the electricity consumption during peak consumption and peak price or moves electricity consumption to some other time. The project Optimisation of Load Control is a part of the EDISON research program for distribution automation. The following areas were studied: Optimization of space heating and ventilation, when electricity price is time variable, load control model in power purchase optimization, optimization of direct load control sequences, interaction between load control optimization and power purchase optimization, literature on load control, optimization methods and field tests and response models of direct load control and the effects of the electricity market deregulation on load control. An overview of the main results is given in this chapter

  2. Beam loading effects in a standing wave accelerator structure

    International Nuclear Information System (INIS)

    Arai, Shigeaki; Katayama, Takeshi; Tojyo, Eiki; Yoshida, Katsuhide.

    1978-11-01

    The steady-state beam loading effects on the accelerating field in the disk-loaded structure of a standing wave type have been systematically studied. The electron bunch from a 15 MeV electron linac is injected at arbitrary phase of the external driving field in the test structure. The change of the phase shift of the accelerating field and that of the stored energy are measured as a function of the phase on which the bunch rides. The former shows drastic change when the bunch is around the crest of the driving field and when the beam loading is heavy, whereas the latter varies sinusoidally for any beam loading. The resonant frequency shift of the structure due to beam loading is estimated by using the measured results. All the experimental results are well explained by the normal mode analysis of the microwave cavity theory. (author)

  3. Heavy flavours in ultra-relativistic heavy ions collisions

    International Nuclear Information System (INIS)

    Rosnet, Ph.

    2008-01-01

    The ultra-relativistic collisions of heavy ions are the today's only means to tackle in laboratory conditions the phase diagram in quantum chromodynamics and the strong interaction. The most recent theoretical studies predict a phase transition between the cold nuclear matter (a hadronic gas) and a plasma of quarks and gluons. Heavy flavour can characterize the nuclear matter produced in a heavy ion collision as well as its spatial-temporal evolution. Their study can be made through their decay into muons. The first part of this work presents the issue of ultra-relativistic heavy ion collisions and the role of heavy flavours. In the second part the author reviews the results of experiments performed at RHIC and particularly presents the analysis of the mass spectrum of dimuons in the Phenix experiment. The third part describes the muon trigger system of the Alice experiment at CERN and the expected performances for the study of di-muons

  4. The motion planning problem and exponential stabilization of a heavy chain. Part II

    OpenAIRE

    Piotr Grabowski

    2008-01-01

    This is the second part of paper [P. Grabowski, The motion planning problem and exponential stabilization of a heavy chain. Part I, to appear in International Journal of Control], where a model of a heavy chain system with a punctual load (tip mass) in the form of a system of partial differential equations was interpreted as an abstract semigroup system and then analysed on a Hilbert state space. In particular, in [P. Grabowski, The motion planning problem and exponential stabilization of a h...

  5. Heavy ion inertial fusion

    International Nuclear Information System (INIS)

    Keefe, D.; Sessler, A.M.

    1980-01-01

    Inertial fusion has not yet been as well explored as magnetic fusion but can offer certain advantages as an alternative source of electric energy for the future. Present experiments use high-power beams from lasers and light-ion diodes to compress the deuterium-tritium (D-T) pellets but these will probably be unsuitable for a power plant. A more promising method is to use intense heavy-ion beams from accelerator systems similar to those used for nuclear and high-energy physics; the present paper addresses itself to this alternative. As will be demonstrated the very high beam power needed poses new design questions, from the ion-source through the accelerating system, the beam transport system, to the final focus. These problems will require extensive study, both theoretically and experimentally, over the next several years before an optimum design for an inertial fusion driver can be arrived at. (Auth.)

  6. Relativistic heavy ion physics

    International Nuclear Information System (INIS)

    Hill, J.C.; Wohn, F.K.

    1993-01-01

    This is a progress report for the period May 1992 through April 1993. The first section, entitled ''Purpose and Trends, gives background on the recent trends in the research program and its evolution from an emphasis on nuclear structure physics to its present emphasis on relativistic heavy ion and RHIC physics. The next section, entitled ''Physics Research Progress'', is divided into four parts: participation in the program to develop a large detector named PHENIX for the RHIC accelerator; joining E864 at the AGS accelerator and the role in that experiment; progress made in the study of electromagnetic dissociation highlight of this endeavor is an experiment carried out with the 197 Au beam from the AGS accelerator in April 1992; progress in completion of the nuclear structure studies. In the final section a list of publications, invited talks, and contributed talks is given

  7. Heavy ion beam probing

    International Nuclear Information System (INIS)

    Hickok, R.L.

    1980-07-01

    This report consists of the notes distributed to the participants at the IEEE Mini-Course on Modern Plasma Diagnostics that was held in Madison, Wisconsin in May 1980. It presents an overview of Heavy Ion Beam Probing that briefly describes the principles and discuss the types of measurements that can be made. The problems associated with implementing beam probes are noted, possible variations are described, estimated costs of present day systems, and the scaling requirements for large plasma devices are presented. The final chapter illustrates typical results that have been obtained on a variety of plasma devices. No detailed calculations are included in the report, but a list of references that will provide more detailed information is included

  8. Heavy ion inertial fusion

    International Nuclear Information System (INIS)

    Keefe, D.; Sessler, A.M.

    1980-07-01

    Inertial fusion has not yet been as well explored as magnetic fusion but can offer certain advantages as an alternative source of electric energy for the future. Present experiments use high-power beams from lasers and light-ion diodes to compress the deuterium-tritium (D-T) pellets but these will probably be unsuitable for a power plant. A more promising method is to use intense heavy-ion beams from accelerator systems similar to those used for nuclear and high-energy physics; the present paper addresses itself to this alternative. As will be demonstrated the very high beam power needed poses new design questions, from the ion source through the accelerating system, the beam transport system, to the final focus. These problems will require extensive study, both theoretically and experimentally, over the next several years before an optimum design for an inertial fusion driver can be arrived at

  9. HEAVY ION LINEAR ACCELERATOR

    Science.gov (United States)

    Van Atta, C.M.; Beringer, R.; Smith, L.

    1959-01-01

    A linear accelerator of heavy ions is described. The basic contributions of the invention consist of a method and apparatus for obtaining high energy particles of an element with an increased charge-to-mass ratio. The method comprises the steps of ionizing the atoms of an element, accelerating the resultant ions to an energy substantially equal to one Mev per nucleon, stripping orbital electrons from the accelerated ions by passing the ions through a curtain of elemental vapor disposed transversely of the path of the ions to provide a second charge-to-mass ratio, and finally accelerating the resultant stripped ions to a final energy of at least ten Mev per nucleon.

  10. Heavy-ion superconducting linacs

    International Nuclear Information System (INIS)

    Delayen, J.R.

    1989-01-01

    This paper reviews the status of the superconducting heavy-ion accelerators. Most of them are linacs used as boosters for tandem electrostatic accelerators, although the technology is being extended to very low velocity to eliminate the need for an injector. The characteristics and features of the various superconducting heavy-ion accelerators are discussed. 45 refs

  11. Heavy-ion superconducting linacs

    Energy Technology Data Exchange (ETDEWEB)

    Delayen, J.R.

    1989-01-01

    This paper reviews the status of the superconducting heavy-ion accelerators. Most of them are linacs used as boosters for tandem electrostatic accelerators, although the technology is being extended to very low velocity to eliminate the need for an injector. The characteristics and features of the various superconducting heavy-ion accelerators are discussed. 45 refs.

  12. Heavy fermion and actinide materials

    International Nuclear Information System (INIS)

    1993-01-01

    During this period, 1/N expansions have been systematically applied to the calculation of the properties of highly correlated electron systems. These studies include examinations of (a) the class of materials known as heavy fermion semi-conductors, (b) the high energy spectra of heavy fermion systems, and (c) the doped oxide superconductors

  13. Heavy metals and soil microbes

    NARCIS (Netherlands)

    Giller, K.E.; Witter, E.; McGrath, S.

    2009-01-01

    The discovery in the early 1980s that soil microorganisms, and in particular the symbiotic bacteria Rhizobium, were highly sensitive to heavy metals initiated a new line of research. This has given us important insights into a range of topics: ecotoxicology, bioavailability of heavy metals, the role

  14. Concentrated loads on concrete

    DEFF Research Database (Denmark)

    Lorenzen, Karen Grøndahl; Nielsen, Mogens Peter

    1997-01-01

    This report deals with concentrated loads on concrete.A new upper bound solution in the axisymmetrical case of a point load in the center of the end face of a cylinder is developed.Based on previous work dealing with failure mechanisms and upper bound solutions, new approximate formulas are devel......This report deals with concentrated loads on concrete.A new upper bound solution in the axisymmetrical case of a point load in the center of the end face of a cylinder is developed.Based on previous work dealing with failure mechanisms and upper bound solutions, new approximate formulas...

  15. Critical Axial Load

    Directory of Open Access Journals (Sweden)

    Walt Wells

    2008-01-01

    Full Text Available Our objective in this paper is to solve a second order differential equation for a long, simply supported column member subjected to a lateral axial load using Heun's numerical method. We will use the solution to find the critical load at which the column member will fail due to buckling. We will calculate this load using Euler's derived analytical approach for an exact solution, as well as Euler's Numerical Method. We will then compare the three calculated values to see how much they deviate from one another. During the critical load calculation, it will be necessary to calculate the moment of inertia for the column member.

  16. Load regulating expansion fixture

    International Nuclear Information System (INIS)

    Wagner, L.M.; Strum, M.J.

    1998-01-01

    A free standing self contained device for bonding ultra thin metallic films, such as 0.001 inch beryllium foils is disclosed. The device will regulate to a predetermined load for solid state bonding when heated to a bonding temperature. The device includes a load regulating feature, whereby the expansion stresses generated for bonding are regulated and self adjusting. The load regulator comprises a pair of friction isolators with a plurality of annealed copper members located there between. The device, with the load regulator, will adjust to and maintain a stress level needed to successfully and economically complete a leak tight bond without damaging thin foils or other delicate components. 1 fig

  17. Laterally loaded masonry

    DEFF Research Database (Denmark)

    Raun Gottfredsen, F.

    In this thesis results from experiments on mortar joints and masonry as well as methods of calculation of strength and deformation of laterally loaded masonry are presented. The strength and deformation capacity of mortar joints have been determined from experiments involving a constant compressive...... stress and increasing shear. The results show a transition to pure friction as the cohesion is gradually destroyed. An interface model of a mortar joint that can take into account this aspect has been developed. Laterally loaded masonry panels have also been tested and it is found to be characteristic...... that laterally loaded masonry exhibits a non-linear load-displacement behaviour with some ductility....

  18. Electrical load modeling

    Energy Technology Data Exchange (ETDEWEB)

    Valgas, Helio Moreira; Pinto, Roberto del Giudice R.; Franca, Carlos [Companhia Energetica de Minas Gerais (CEMIG), Belo Horizonte, MG (Brazil); Lambert-Torres, Germano; Silva, Alexandre P. Alves da; Pires, Robson Celso; Costa, Junior, Roberto Affonso [Escola Federal de Engenharia de Itajuba, MG (Brazil)

    1994-12-31

    Accurate dynamic load models allow more precise calculations of power system controls and stability limits, which are critical mainly in the operation planning of power systems. This paper describes the development of a computer program (software) for static and dynamic load model studies using the measurement approach for the CEMIG system. Two dynamic load model structures are developed and tested. A procedure for applying a set of measured data from an on-line transient recording system to develop load models is described. (author) 6 refs., 17 figs.

  19. Heavy charged particle therapy

    International Nuclear Information System (INIS)

    Mizoe, Jun-etsu

    1995-01-01

    A pilot study of heavy charged particles with heavy ion medical accelerator in Chiba (HIMAC) for advanced H and N cancer has been carried out from June 1994 at National Institute of Radiological Sciences (NIRS). As of the beginning of August 1994, three patients were treated by 290 MeV carbon ions. The patients had adenocarcinoma of the cheek mucosa, squamous cell carcinoma of the ethmoid sinus and adenoid cystic carcinoma of the sublingual gland. Patients were immobilized by individual head coach and thermosplint facial shell. Individual collimators and bolus were also prepared for each ports. Dose fractionation for the initial pilot study group was 16.2 GyE/18 fractions/6 weeks, which would be equivalent to standard fractionation of 60.0 Gy/30 fractions/6 weeks with photons. This dose fractionation was considered to be 20% lesser than 75 GyE/37.5 fractions/7.5 weeks, which is estimated to be maximum tolerance dose for advanced H and N cancers. HIMAC worked well and there was no major trouble causing any treatment delay. Acute skin reactions of 3 patients were 2 cases of bright erythema with patchy moist desquamation and one of dull erythema, which were evaluated as equivalent reaction with irradiated dose. Acute mucosa reactions appeared to have lesser reaction than predicted mucositis. Tumor reactions of three patients were partial reaction (PR) at the end of treatment and nearly complete remission (CR) after 6 months of treatment. From October 1994, we started to treat patients with advanced H and N cancer with 10% high dose than previous dose. And new candidates of pilot study with non small cell lung cancer, brain tumor and carcinoma of the tongue were entered into pilot study. At the end of February 1995, a total of 21 patients were treated by carbon ions. (J.P.N.)

  20. Results of heavy ion radiotherapy

    International Nuclear Information System (INIS)

    Castro, J.R.

    1994-04-01

    The potential of heavy ion therapy for clinical use in cancer therapy stems from the biological parameters of heavy charged particles, and their precise dose localization. Biologically, carbon, neon and other heavy ion beams (up to about silicon) are clinically useful in overcoming the radioresistance of hypoxic tumors, thus increasing biological effectiveness relative to low-LET x-ray or electron beams. Cells irradiated by heavy ions show less variation in cell-cycle related radiosensitivity and decreased repair of radiation injury. The physical parameters of these heavy charged particles allow precise delivery of high radiation doses to tumors while minimizing irradiation of normal tissues. Clinical use requires close interaction between radiation oncologists, medical physicists, accelerator physicists, engineers, computer scientists and radiation biologists

  1. Heavy metal sorption by microalgae

    International Nuclear Information System (INIS)

    Sandau, E.; Sandau, P.; Pulz, O.

    1996-01-01

    Viable microalgae are known to be able to accumulate heavy metals (bioaccumulation). Against a background of the increasing environmental risks caused by heavy metals, the microalgae Chlorella vulgaris and Spirulina platensis and their potential for the biological removal of heavy metals from aqueous solutions were taken as an example for investigation. Small-scale cultivation tests (50 l) with Cd-resistant cells of Chlorella vulgaris have shown that approx. 40% of the added 10 mg Cd/l was removed from the solution within seven days. At this heavy metal concentration sensitive cells died. Non-viable microalgae are able to eliminate heavy metal ions in a short time by biosorption in uncomplicated systems, without any toxicity problems. Compared with original biomasses, the sorption capacity of microalgal by-products changes only insignificantly. Their low price makes them economical. (orig.)

  2. Baryons in the heavy quark effective theory

    International Nuclear Information System (INIS)

    Mannel, T.; Roberts, W.; Ryzak, Z.

    1990-08-01

    We show how to incorporate baryons in the heavy quark effective theory. A convenient formalism is exhibited and applied to semileptonic weak decays of heavy baryons and to exclusive production of heavy baryons in e + e - annihilation. (orig.)

  3. Experimental study into a hybrid PCCI/CI concept for next-generation heavy-duty diesel engines

    NARCIS (Netherlands)

    Doosje, E.; Willems, F.P.T.; Baert, R.S.G.; Dijk, M.D. van

    2012-01-01

    This paper presents the first results of an experimental study into a hybrid combustion concept for next-generation heavy-duty diesel engines. In this hybrid concept, at low load operating conditions, the engine is run in Pre-mixed Charge Compression Ignition (PCCI) mode, whereas at high load

  4. Load Balancing in Hypergraphs

    Science.gov (United States)

    Delgosha, Payam; Anantharam, Venkat

    2018-03-01

    Consider a simple locally finite hypergraph on a countable vertex set, where each edge represents one unit of load which should be distributed among the vertices defining the edge. An allocation of load is called balanced if load cannot be moved from a vertex to another that is carrying less load. We analyze the properties of balanced allocations of load. We extend the concept of balancedness from finite hypergraphs to their local weak limits in the sense of Benjamini and Schramm (Electron J Probab 6(23):13, 2001) and Aldous and Steele (in: Probability on discrete structures. Springer, Berlin, pp 1-72, 2004). To do this, we define a notion of unimodularity for hypergraphs which could be considered an extension of unimodularity in graphs. We give a variational formula for the balanced load distribution and, in particular, we characterize it in the special case of unimodular hypergraph Galton-Watson processes. Moreover, we prove the convergence of the maximum load under some conditions. Our work is an extension to hypergraphs of Anantharam and Salez (Ann Appl Probab 26(1):305-327, 2016), which considered load balancing in graphs, and is aimed at more comprehensively resolving conjectures of Hajek (IEEE Trans Inf Theory 36(6):1398-1414, 1990).

  5. Structural load combinations

    International Nuclear Information System (INIS)

    Hwang, H.; Reich, M.; Ellingwood, B.; Shinozuka, M.

    1985-01-01

    This paper presents the latest results of the program entitled, ''Probability Based Load Combinations For Design of Category I Structures''. In FY 85, a probability-based reliability analysis method has been developed to evaluate safety of shear wall structures. The shear walls are analyzed using stick models with beam elements and may be subjected to dead load, live load and in-plane eqrthquake. Both shear and flexure limit states are defined analytically. The limit state probabilities can be evaluated on the basis of these limit states. Utilizing the reliability analysis method mentioned above, load combinations for the design of shear wall structures have been established. The proposed design criteria are in the load and resistance factor design (LRFD) format. In this study, the resistance factors for shear and flexure and load factors for dead and live loads are preassigned, while the load factor for SSE is determined for a specified target limit state probability of 1.0 x 10 -6 or 1.0 x 10 -5 during a lifetime of 40 years. 23 refs., 9 tabs

  6. Load Induced Blindness

    Science.gov (United States)

    Macdonald, James S. P.; Lavie, Nilli

    2008-01-01

    Although the perceptual load theory of attention has stimulated a great deal of research, evidence for the role of perceptual load in determining perception has typically relied on indirect measures that infer perception from distractor effects on reaction times or neural activity (see N. Lavie, 2005, for a review). Here we varied the level of…

  7. Structural load combinations

    International Nuclear Information System (INIS)

    Hwang, H.; Reich, M.; Ellingwood, B.; Shinozuka, M.

    1986-01-01

    This paper presents the latest results of the program entitled, ''Probability Based Load Combinations For Design of Category I Structures''. In FY 85, a probability-based reliability analysis method has been developed to evaluate safety of shear wall structures. The shear walls are analyzed using stick models with beam elements and may be subjected to dead load, live load and in-plane earthquake. Both shear and flexure limit states are defined analytically. The limit state probabilities can be evaluated on the basis of these limit states. Utilizing the reliability analysis method mentioned above, load combinations for the design of shear wall structures have been established. The proposed design criteria are in the load and resistance factor design (LRFD) format. In this study, the resistance factors for shear and flexure and load factors for dead and live loads are preassigned, while the load factor for SSE is determined for a specified target limit state probability of 1.0 x 10 -6 or 1.0 x 10 -5 during a lifetime of 40 years

  8. Load event: Aircraft crash

    International Nuclear Information System (INIS)

    Fritsch, H.

    1985-01-01

    The bibliography includes 48 quotations, up to the year 1983, on the following issues: Experiments and computational methods. Design load for the dimensioning of reinforced concrete buildings and components with respect to the dynamic load in the event of an aircraft crash. (orig./HP) [de

  9. Characterizing heavy metal build-up on urban road surfaces: Implication for stormwater reuse

    International Nuclear Information System (INIS)

    Liu, An; Liu, Liang; Li, Dunzhu; Guan, Yuntao

    2015-01-01

    Stormwater reuse is increasingly popular in the worldwide. In terms of urban road stormwater, it commonly contains toxic pollutants such as heavy metals, which could undermine the reuse safety. The research study investigated heavy metal build-up characteristics on urban roads in a typical megacity of South China. The research outcomes show the high variability in heavy metal build-up loads among different urban road sites. The degree of traffic congestion and road surface roughness was found to exert a more significant influence on heavy metal build-up rather than traffic volume. Due to relatively higher heavy metal loads, stormwater from roads with more congested traffic conditions or rougher surfaces might be suitable for low-water-quality required activities while the stormwater from by-pass road sections could be appropriate for relatively high-water-quality required purposes since the stormwater could be relatively less polluted. Based on the research outcomes, a decision-making process for heavy metals based urban road stormwater reuse was proposed. The new finding highlights the importance to undertaking a “fit-for-purpose” road stormwater reuse strategy. Additionally, the research results can also contribute to enhancing stormwater reuse safety. - Highlights: • Heavy metal (HM) build-up varies with traffic and road surface conditions. • Traffic congestion and surface roughness exert a higher impact on HM build-up. • A “fit-for-purpose” strategy could suit urban road stormwater reuse

  10. Characterizing heavy metal build-up on urban road surfaces: Implication for stormwater reuse

    Energy Technology Data Exchange (ETDEWEB)

    Liu, An [Research Centre of Environmental Engineering and Management, Graduate School at Shenzhen, Tsinghua University, 518055 Shenzhen (China); Cooperative Research and Education Centre for Environmental Technology, Kyoto University–Tsinghua University, 518055 Shenzhen (China); Liu, Liang; Li, Dunzhu [Research Centre of Environmental Engineering and Management, Graduate School at Shenzhen, Tsinghua University, 518055 Shenzhen (China); Guan, Yuntao, E-mail: guanyt@tsinghua.edu.cn [Research Centre of Environmental Engineering and Management, Graduate School at Shenzhen, Tsinghua University, 518055 Shenzhen (China); School of Environment, Tsinghua University, Beijing 100084 (China)

    2015-05-15

    Stormwater reuse is increasingly popular in the worldwide. In terms of urban road stormwater, it commonly contains toxic pollutants such as heavy metals, which could undermine the reuse safety. The research study investigated heavy metal build-up characteristics on urban roads in a typical megacity of South China. The research outcomes show the high variability in heavy metal build-up loads among different urban road sites. The degree of traffic congestion and road surface roughness was found to exert a more significant influence on heavy metal build-up rather than traffic volume. Due to relatively higher heavy metal loads, stormwater from roads with more congested traffic conditions or rougher surfaces might be suitable for low-water-quality required activities while the stormwater from by-pass road sections could be appropriate for relatively high-water-quality required purposes since the stormwater could be relatively less polluted. Based on the research outcomes, a decision-making process for heavy metals based urban road stormwater reuse was proposed. The new finding highlights the importance to undertaking a “fit-for-purpose” road stormwater reuse strategy. Additionally, the research results can also contribute to enhancing stormwater reuse safety. - Highlights: • Heavy metal (HM) build-up varies with traffic and road surface conditions. • Traffic congestion and surface roughness exert a higher impact on HM build-up. • A “fit-for-purpose” strategy could suit urban road stormwater reuse.

  11. Load responsive multilayer insulation performance testing

    International Nuclear Information System (INIS)

    Dye, S.; Kopelove, A.; Mills, G. L.

    2014-01-01

    Cryogenic insulation designed to operate at various pressures from one atmosphere to vacuum, with high thermal performance and light weight, is needed for cryogenically fueled space launch vehicles and aircraft. Multilayer insulation (MLI) performs well in a high vacuum, but the required vacuum shell for use in the atmosphere is heavy. Spray-on foam insulation (SOFI) is often used in these systems because of its light weight, but can have a higher heat flux than desired. We report on the continued development of Load Responsive Multilayer Insulation (LRMLI), an advanced thermal insulation system that uses dynamic beam discrete spacers that provide high thermal performance both in atmosphere and vacuum. LRMLI consists of layers of thermal radiation barriers separated and supported by micromolded polymer spacers. The spacers have low thermal conductance, and self-support a thin, lightweight vacuum shell that provides internal high vacuum in the insulation. The dynamic load responsive spacers compress to support the external load of a vacuum shell in one atmosphere, and decompress under reduced atmospheric pressure for lower heat leak. Structural load testing was performed on the spacers with various configurations. LRMLI was installed on a 400 liter tank and boil off testing with liquid nitrogen performed at various chamber pressures from one atmosphere to high vacuum. Testing was also performed with an MLI blanket on the outside of the LRMLI

  12. Load responsive multilayer insulation performance testing

    Energy Technology Data Exchange (ETDEWEB)

    Dye, S.; Kopelove, A. [Quest Thermal Group, 6452 Fig Street Suite A, Arvada, CO 80004 (United States); Mills, G. L. [Ball Aerospace and Technologies Corp, 1600 Commerce Street, Boulder, CO 80301 (United States)

    2014-01-29

    Cryogenic insulation designed to operate at various pressures from one atmosphere to vacuum, with high thermal performance and light weight, is needed for cryogenically fueled space launch vehicles and aircraft. Multilayer insulation (MLI) performs well in a high vacuum, but the required vacuum shell for use in the atmosphere is heavy. Spray-on foam insulation (SOFI) is often used in these systems because of its light weight, but can have a higher heat flux than desired. We report on the continued development of Load Responsive Multilayer Insulation (LRMLI), an advanced thermal insulation system that uses dynamic beam discrete spacers that provide high thermal performance both in atmosphere and vacuum. LRMLI consists of layers of thermal radiation barriers separated and supported by micromolded polymer spacers. The spacers have low thermal conductance, and self-support a thin, lightweight vacuum shell that provides internal high vacuum in the insulation. The dynamic load responsive spacers compress to support the external load of a vacuum shell in one atmosphere, and decompress under reduced atmospheric pressure for lower heat leak. Structural load testing was performed on the spacers with various configurations. LRMLI was installed on a 400 liter tank and boil off testing with liquid nitrogen performed at various chamber pressures from one atmosphere to high vacuum. Testing was also performed with an MLI blanket on the outside of the LRMLI.

  13. Toxicity of heavy metals in the environment

    National Research Council Canada - National Science Library

    Oehme, F.W

    1978-01-01

    ... as the fundamental mechanisms of toxicity resulting from heavy metal chemicals. The more common toxic heavy metals, along with their biochemistry and associated clinical syndromes, are then described...

  14. Interaction of soil heavy metal pollution with industrialisation and the landscape pattern in Taiyuan city, China.

    Science.gov (United States)

    Liu, Yong; Su, Chao; Zhang, Hong; Li, Xiaoting; Pei, Jingfei

    2014-01-01

    Many studies indicated that industrialization and urbanization caused serious soil heavy metal pollution from industrialized age. However, fewer previous studies have conducted a combined analysis of the landscape pattern, urbanization, industrialization, and heavy metal pollution. This paper was aimed at exploring the relationships of heavy metals in the soil (Pb, Cu, Ni, As, Cd, Cr, Hg, and Zn) with landscape pattern, industrialisation, urbanisation in Taiyuan city using multivariate analysis. The multivariate analysis included correlation analysis, analysis of variance (ANOVA), independent-sample T test, and principal component analysis (PCA). Geographic information system (GIS) was also applied to determine the spatial distribution of the heavy metals. The spatial distribution maps showed that the heavy metal pollution of the soil was more serious in the centre of the study area. The results of the multivariate analysis indicated that the correlations among heavy metals were significant, and industrialisation could significantly affect the concentrations of some heavy metals. Landscape diversity showed a significant negative correlation with the heavy metal concentrations. The PCA showed that a two-factor model for heavy metal pollution, industrialisation, and the landscape pattern could effectively demonstrate the relationships between these variables. The model explained 86.71% of the total variance of the data. Moreover, the first factor was mainly loaded with the comprehensive pollution index (P), and the second factor was primarily loaded with landscape diversity and dominance (H and D). An ordination of 80 samples could show the pollution pattern of all the samples. The results revealed that local industrialisation caused heavy metal pollution of the soil, but such pollution could respond negatively to the landscape pattern. The results of the study could provide a basis for agricultural, suburban, and urban planning.

  15. From heavy nuclei to super-heavy nuclei

    International Nuclear Information System (INIS)

    Theisen, Ch.

    2003-01-01

    The existence of super-heavy nuclei has been predicted nearly fifty years ago. Due to the strong coulomb repulsion, the stabilisation of these nuclei is possible only through shell effects. The reasons for this fragile stability, as well as the theoretical predictions concerning the position of the island of stability are presented in the first part of this lecture. In the second part, experiments and experimental techniques which have been used to synthesize or search for super-heavy elements are described. Spectroscopic studies performed in very heavy elements are presented in the following section. We close this lecture with techniques that are currently being developed in order to reach the superheavy island and to study the structure of very-heavy nuclei. (author)

  16. Heavy Water - Industrial Separation Processes

    International Nuclear Information System (INIS)

    Peculea, M.

    1984-01-01

    This monograph devoted to the heavy water production mainly presents the Romanian experience in the field which started in early sixties from the laboratory scale production and reached now the level of large scale industrial production at ROMAG-Drobeta, Romania. The book is structured in eleven chapters entitled: Overview, The main physical properties, Sources, Uses, Separation factor and equilibrium constant, Mathematical modelling of the separation process, Thermodynamical considerations on the isotope separation, Selection criteria for heavy water separation processes, Industrial installations for heavy water production, Prospects, Acknowledgements. 200 Figs., 90 Tabs., 135 Refs

  17. Heavy quark fragmentation functions in the heavy quark effective theory

    International Nuclear Information System (INIS)

    Martynenko, A.P.; Saleev, V.A.

    1996-01-01

    The fragmentation of b-bar-antiquark into polarized B c * -mesons and b-quark into P-wave (c-bar b) states in the Heavy Quark Effective Theory. The heavy quark fragmentation functions in longitudinally and transversely polarized S-wave b-bar c-states and P-wave mesons containing b-, c-quarks also, with the exact account of corrections of first order in 1/m b . 20 refs., 2 figs

  18. Heavy-element nucleosynthesis

    International Nuclear Information System (INIS)

    Mathews, G.J.

    1990-01-01

    New measurements and theoretical studies of nuclear properties, together with new astronomical data on the growth of heavy-element abundances during the early history of the Galaxy, now provide a clearer picture of where in nature the elements heavier than iron are produced by rapid (r-process) and show (s-process) neutron capture reactions. The nuclear data suggest that the r-process involves a high-neutron-density beta-flow equilibrium environment and that the s-process may have occurred at a temperature and neutron density consistent with a 13 C(α,n) 16 0 neutron source. The astronomical data, when compared with simple galactic chemical evolution modes, suggests that the r-process is associated with type II supernovae and that the neutron source must be manufactured by the star. Low-mass type II supernovae are proposed as the most important contributors to the r-process. A 13 C neutron source in intermediate-mass stars is proposed for the s-process. 64 refs., 7 figs

  19. Heavy ion fusion sources

    International Nuclear Information System (INIS)

    Grote, D.P.; Kwan, J.; Westenskow, G.

    2003-01-01

    In Heavy-Fusion and in other applications, there is a need for high brightness sources with both high current and low emittance. The traditional design with a single monolithic source, while very successful, has significant constraints on it when going to higher currents. With the Child-Langmuir current-density limit, geometric aberration limits, and voltage breakdown limits, the area of the source becomes a high power of the current, A ∼ I 8/3 . We are examining a multi-beamlet source, avoiding the constraints by having many beamlets each with low current and small area. The beamlets are created and initially accelerated separately and then merged to form a single beam. This design offers a number of potential advantages over a monolithic source, such as a smaller transverse footprint, more control over the shaping and aiming of the beam, and more flexibility in the choice of ion sources. A potential drawback, however, is the emittance that results from the merging of the beamlets. We have designed injectors using simulation that have acceptably low emittance and are beginning to examine them experimentally

  20. Heavy fields and gravity

    Energy Technology Data Exchange (ETDEWEB)

    Goon, Garrett [Institute of Physics, Universiteit van Amsterdam,Science Park 904, Amsterdam, 1090 GL (Netherlands)

    2017-01-11

    We study the effects of heavy fields on 4D spacetimes with flat, de Sitter and anti-de Sitter asymptotics. At low energies, matter generates specific, calculable higher derivative corrections to the GR action which perturbatively alter the Schwarzschild-(A)dS family of solutions. The effects of massive scalars, Dirac spinors and gauge fields are each considered. The six-derivative operators they produce, such as ∼R{sup 3} terms, generate the leading corrections. The induced changes to horizon radii, Hawking temperatures and entropies are found. Modifications to the energy of large AdS black holes are derived by imposing the first law. An explicit demonstration of the replica trick is provided, as it is used to derive black hole and cosmological horizon entropies. Considering entropy bounds, it’s found that scalars and fermions increase the entropy one can store inside a region bounded by a sphere of fixed size, but vectors lead to a decrease, oddly. We also demonstrate, however, that many of the corrections fall below the resolving power of the effective field theory and are therefore untrustworthy. Defining properties of black holes, such as the horizon area and Hawking temperature, prove to be remarkably robust against higher derivative gravitational corrections.

  1. Heavy ion elastic scatterings

    International Nuclear Information System (INIS)

    Mermaz, M.C.

    1984-01-01

    Diffraction and refraction play an important role in particle elastic scattering. The optical model treats correctly and simultaneously both phenomena but without disentangling them. Semi-classical discussions in terms of trajectories emphasize the refractive aspect due to the real part of the optical potential. The separation due to to R.C. Fuller of the quantal cross section into two components coming from opposite side of the target nucleus allows to understand better the refractive phenomenon and the origin of the observed oscillations in the elastic scattering angular distributions. We shall see that the real part of the potential is responsible of a Coulomb and a nuclear rainbow which allows to determine better the nuclear potential in the interior region near the nuclear surface since the volume absorption eliminates any effect of the real part of the potential for the internal partial scattering waves. Resonance phenomena seen in heavy ion scattering will be discussed in terms of optical model potential and Regge pole analysis. Compound nucleus resonances or quasi-molecular states can be indeed the more correct and fundamental alternative

  2. Relativistic heavy ion research

    International Nuclear Information System (INIS)

    1992-01-01

    Experimental work is reported on the following topics: transverse energy production in 10.7-GeV/c/u Au on Au collisions; first results on delta ray production and charged particle multiplicities with the Au beam at 10.7 GeV/c/A; preliminary studies on the feasibility of flow measurement with the E814 participant calorimeter; preliminary results from the E877 telescope; and low-p t baryon distribution in Si+Al, Pb collisions at the AGS. Then the status of the Hadronic Calorimeter project of AGS Experiment E864 (ECOS--Exotic Composite Object Spectrometer) is reviewed. Next, the same is done for work of the STAR RHIC collaboration (Silicon Vertex Tracker (SVT) project evolution and development in FY92, SVT software results from 1992, SVT instrumentation, FY93 SVT pion test beam). The instrumentation section deals with the design and installation of a target rapidity telescope for BNL experiment 814/877 and a repair scheme for the E814/E877 participant calorimeter. Finally, the theory part addresses bosonic kinetics: thermalization of mesons and the pion p perpendicular spectrum in ultrarelativistic heavy-ion collisions and non-equilibrium properties of hadronic mixtures

  3. Heavy quarks and leptons

    International Nuclear Information System (INIS)

    Azimov, Ya.I.; Khoze, V.A.

    1979-01-01

    Experimental results which proved the reality of quarks are reviewed along with further experiments broadening the representation of quarks and leptons and providing the basis to develop the theory of elementary particles. The discovery of the J/psi particle is noted to give rise to the discovery of c-quark, the existance of which is confirmed by the discovery of charmed hadrons. The main aspects of quantum chromodynamics explaining the mechanism of strong interaction of quarks are considered along with those of the Weinberg-Salam theory proposed to describe weak and electromagnetic interactions of quarks and leptons. Experimental data testifying to the existance of heavy tausup(+-) leptons are presented. The history of discovery of γ mesons and of a new heavier b-quark is described. Perspectives for studying elementary particles are discussed. Further studies of γ mesons, discovery and investigation of charmed particles are noted to be immediate tasks along with the search for manifestation of t-quark considered to be a partner of b-quark from the viewpoint of the Weinberg-Salam model

  4. Heavy particle effects

    International Nuclear Information System (INIS)

    Yao, Y.P.

    1981-01-01

    There are two problems discussed, both of which have to do with dissimilar magnitudes in mass. Theoretically, we can devise the large difference in mass as observed by decreeing some vev, v/sub i/ to be much bigger than the other; or, we can assume that some couplings g/sub i/ are much stronger. These two different assumptions give rise to entirely different patterns of interaction in the resulting theory. The first way to generate a mass hierarchy can be called the soft way, because in the zeroth order, the large mass scale leaves its foot print merely in a few effective parameters of the residual theory. The effective theory is renormalizable, sans anomaly. In this limit, the heavy particles decouple. The second assumption (g/sub j/ much greater than g/sub j'/) to create mass hierarchy does a lot of violence to a theory. Effects of the large mass scale will be felt by the system left behind in many ways. An infinite number of parameters are needed to summarize the effects in this limit. This is called the hard limit. It follows that the resulting effective Lagrangian, if in fact it makes sense to construct one at all, will be non-polynomial and apparently non-renormalizable

  5. Heavy Flavor Production in Heavy Ion Collisions at CMS

    CERN Document Server

    Sun, Jian

    2016-01-01

    Studies of Heavy flavor production are of great interest in heavy ion collisions. In the produced medium, the binding potential between a quark and antiquark in quarkonium is screened by surrounding light quarks and antiquarks. Thus, the various quarkonium states are expected to be melt at different temperatures depending on their binding energies, which allows us to characterize the QCD phase transition. In addition, open heavy flavor production are relevant for flavor-dependence of the in-medium parton energy loss. In QCD, gluons are expected to lose more energy compared to quarks when passing through the QGP due to the larger color charge. Compared to light quarks, heavy quarks are expected to lose less radiative energy because gluon radiation is suppressed at angles smaller than the ratio of the quark mass to its energy. This dead cone effect (and its disappearance at high transverse momentum) can be studied using open heavy flavor mesons and heavy flavor tagged jets. With CMS detector, quarkonia, open he...

  6. Load Balancing Scientific Applications

    Energy Technology Data Exchange (ETDEWEB)

    Pearce, Olga Tkachyshyn [Texas A & M Univ., College Station, TX (United States)

    2014-12-01

    The largest supercomputers have millions of independent processors, and concurrency levels are rapidly increasing. For ideal efficiency, developers of the simulations that run on these machines must ensure that computational work is evenly balanced among processors. Assigning work evenly is challenging because many large modern parallel codes simulate behavior of physical systems that evolve over time, and their workloads change over time. Furthermore, the cost of imbalanced load increases with scale because most large-scale scientific simulations today use a Single Program Multiple Data (SPMD) parallel programming model, and an increasing number of processors will wait for the slowest one at the synchronization points. To address load imbalance, many large-scale parallel applications use dynamic load balance algorithms to redistribute work evenly. The research objective of this dissertation is to develop methods to decide when and how to load balance the application, and to balance it effectively and affordably. We measure and evaluate the computational load of the application, and develop strategies to decide when and how to correct the imbalance. Depending on the simulation, a fast, local load balance algorithm may be suitable, or a more sophisticated and expensive algorithm may be required. We developed a model for comparison of load balance algorithms for a specific state of the simulation that enables the selection of a balancing algorithm that will minimize overall runtime.

  7. Status of load management

    Energy Technology Data Exchange (ETDEWEB)

    Juchymenko, A

    1983-08-01

    A summary is presented of the status of load management, defined as any activity by an electric utility to affect the size and characteristics of its load. Load management is currently viewed by electric utilities as an important tool for marketing electricity in a competitive fuel situation. A major aim of the National Energy Program is to reduce Canada's dependence on oil by 1990 to 10% of the energy used by all markets. As a result, electricity may play a greater role in the supply of primary energy. Research in load management has been directed mostly towards the residential market, especially direct control of domestic hot water heaters and air conditioners. Studies conducted in Canada and the U.S. to determine user's receptiveness to direct control of loads and thermal energy storage systems indicate that these load management techniques are in most cases not acceptable to customers, who prefer voluntary reduction in demand. The potential exists in the industrial market to use load management to assist in electrifying many of the fossil fuel-fired processes at competitive energy prices. Some of the more important applications include an industrial heat pump to heat liquids to 120{degree}C, induction heating for melting and heat treating of metals, and mechanical vapor recompression equipment to produce proces steam. 21 refs., 2 figs., 2 tabs.

  8. Heavy quark and magnetic moment

    International Nuclear Information System (INIS)

    Mubarak, Ahmad; Jallu, M.S.

    1979-01-01

    The magnetic moments and transition moments of heavy hadrons including the conventional particles are obtained under the SU(5) truth symmetry scheme. To this end state vectors are defined and the quark additivity principle is taken into account. (author)

  9. Heavy flavour production at LHCb

    CERN Document Server

    Barsuk, Sergey

    2016-01-01

    The present write-up reports recent LHCb results on production of quarkonium and open flavour states, as well as selected results on associated production, central exclusive production and pro- duction in heavy ion collisions.

  10. Principles of heavy oil recovery

    Energy Technology Data Exchange (ETDEWEB)

    Szasz, S.E.; Thomas, G.W.

    1965-10-01

    Rising exploration costs have prompted greater interest in the large known deposits of heavy oil in North America. Because of high oil viscosities in such reservoirs, recoveries are poor, fluid drives are inefficient and production rates are uneconomical. Viscosity reduction can best be accomplished by heating the reservoir. The basic aspects of reservoir heating are reviewed and those processes which are of practical importance in heavy oil reservoirs are discussed. Wellbore heating frequently can be applied to heavy oil reservoirs to increase production rates. In hot waterflooding, the water requirements are much higher than an ordinary waterflood. Steam floods are more attractive, but operating costs are generally high. Conduction heating processes appear most promising. Among these is included the cyclic steam-soak process. A simple method is presented for estimating the performance from the first cycle of steam injection into the formation, assuming gravity as the only driving energy. An example calculation for a typical heavy oil reservoir is given. (26 refs.)

  11. The Canadian heavy water situation

    International Nuclear Information System (INIS)

    Dahlinger, A.

    The Canadian heavy water industry is analyzed. Supply and demand are predicted through 1985. Pricing is broken down into components. Backup R and D contributes greatly to process improvements. (E.C.B.)

  12. Heavy quark spectroscopy and decay

    International Nuclear Information System (INIS)

    Schindler, R.H.

    1987-01-01

    The understanding of q anti q systems containing heavy, charmed, and bottom quarks has progressed rapidly in recent years, through steady improvements in experimental techniques for production and detection of their decays. These lectures are meant to be an experimentalist's review of the subject. In the first of two lectures, the existing data on the spectroscopy of the bound c anti c and b anti b systems will be discussed. Emphasis is placed on comparisons with the theoretical models. The second lecture covers the rapidly changing subject of the decays of heavy mesons (c anti q and b anti q), and their excited states. In combination, the spectroscopy and decays of heavy quarks are shown to provide interesting insights into both the strong and electroweak interactions of the heavy quarks. 103 refs., 39 figs

  13. Structure Optimal Design of Electromagnetic Levitation Load Reduction Device for Hydroturbine Generator Set

    Directory of Open Access Journals (Sweden)

    Qingyan Wang

    2015-01-01

    Full Text Available Thrust bearing is one part with the highest failure rate in hydroturbine generator set, which is primarily due to heavy axial load. Such heavy load often makes oil film destruction, bearing friction, and even burning. It is necessary to study the load and the reduction method. The dynamic thrust is an important factor to influence the axial load and reduction design of electromagnetic device. Therefore, in the paper, combined with the structure features of vertical turbine, the hydraulic thrust is analyzed accurately. Then, take the turbine model HL-220-LT-550, for instance; the electromagnetic levitation load reduction device is designed, and its mathematical model is built, whose purpose is to minimize excitation loss and total quality under the constraints of installation space, connection layout, and heat dissipation. Particle swarm optimization (PSO is employed to search for the optimum solution; finally, the result is verified by finite element method (FEM, which demonstrates that the optimized structure is more effective.

  14. Geochemical Model And Normalization For Heavy Metals In The Bottom Sediments, Dubai, UAE.

    OpenAIRE

    El Sammak, A.A. [عمرو عبدالعزيز السماك

    1999-01-01

    Dubai creek can be considered as the focal point of Dubai. It has great importance for trading and aesthetic values. Total and leachable heavy metals (Cd, Co, Ni, Pb and Zn), organic carbon and total carbonate were studied in the bottom sediments of the creek. Pollution Load Index, statistical analysis, were used in order to quantify the pollution load as well as to discriminate the data into significant groups. Normalization of the data using organic carbon and total carbonate was done in or...

  15. Heavy Metal Stars

    Science.gov (United States)

    2001-08-01

    La Silla Telescope Detects Lots of Lead in Three Distant Binaries Summary Very high abundances of the heavy element Lead have been discovered in three distant stars in the Milky Way Galaxy . This finding strongly supports the long-held view that roughly half of the stable elements heavier than Iron are produced in common stars during a phase towards the end of their life when they burn their Helium - the other half results from supernova explosions. All the Lead contained in each of the three stars weighs about as much as our Moon. The observations show that these "Lead stars" - all members of binary stellar systems - have been more enriched with Lead than with any other chemical element heavier than Iron. This new result is in excellent agreement with predictions by current stellar models about the build-up of heavy elements in stellar interiors. The new observations are reported by a team of Belgian and French astronomers [1] who used the Coude Echelle Spectrometer on the ESO 3.6-m telescope at the La Silla Observatory (Chile). PR Photo 26a/01 : A photo of HD 196944 , one of the "Lead stars". PR Photo 26b/01 : A CES spectrum of HD 196944 . The build-up of heavy elements Astronomers and physicists denote the build-up of heavier elements from lighter ones as " nucleosynthesis ". Only the very lightest elements (Hydrogen, Helium and Lithium [2]) were created at the time of the Big Bang and therefore present in the early universe. All the other heavier elements we now see around us were produced at a later time by nucleosynthesis inside stars. In those "element factories", nuclei of the lighter elements are smashed together whereby they become the nuclei of heavier ones - this process is known as nuclear fusion . In our Sun and similar stars, Hydrogen is being fused into Helium. At some stage, Helium is fused into Carbon, then Oxygen, etc. The fusion process requires positively charged nuclei to move very close to each other before they can unite. But with increasing

  16. Exotic heavy baryons at LHC

    International Nuclear Information System (INIS)

    Biro, T.S.; Zimanyi, J.

    1993-06-01

    A heavy bottom-charm six-quark baryon is considered. A semiclassical and a Gaussian estimate show that the octet-octet bbb-ccc configuration can be favoured energetically rather than the singlet-singlet one. This result suggests that a confined bbb-ccc six-quark state may exist. Such objects may be produced in suitable amounts by heavy-ion collisions at Large Hadronic Collider energies. (R.P.) 8 refs. 1 fig

  17. Heavy leptons at hadron colliders

    International Nuclear Information System (INIS)

    Ohnemus, J.E.

    1987-01-01

    The recent advent of high energy hadron colliders capable of producing weak bosons has opened new vistas for particle physics research, including the search for a possible fourth generation heavy charged lepton, which is the primary topic of the thesis. Signals for identifying a new heavy lepton have been calculated and compared to Standard Model backgrounds. Results are presented for signals at the CERN collider, the Fermilab collider, and the proposed Superconducting Supercollider

  18. Heavy Ion Physics at LHC

    CERN Document Server

    Valenti, G.

    2002-01-01

    The study of heavy ion interactions constitutes an important part of the experimental program outlined for the Large Hadron Collider under construction at CERN and expected to be operational by 2006. ALICE 1 is the single detector having the capabilities to explore at the same time most of the characteristics of high energy heavy ion interactions. Specific studies of jet quenching and quarkonia production, essentially related to µ detection are also planned by CMS 2 .

  19. BNL heavy ion fusion program

    International Nuclear Information System (INIS)

    Maschke, A.W.

    1978-01-01

    A principal attraction of heavy ion fusion is that existing accelerator technology and theory are sufficiently advanced to allow one to commence the design of a machine capable of igniting thermonuclear explosions. There are, however, a number of features which are not found in existing accelerators built for other purposes. The main thrust of the BNL Heavy Ion Fusion program has been to explore these features. Longitudinal beam bunching, very low velocity acceleration, and space charge neutralization are briefly discussed

  20. The Canadian heavy water situation

    International Nuclear Information System (INIS)

    Dahlinger, A.

    1975-08-01

    Existing heavy water plants in Canada are producing at a satisfactory rate and currently planned capacity is in balance with projected needs. By 1980, we shall have Girdler-Sulphide plants installed with a design capacity of almost 600 kg/h. Effort is required to minimize production costs for heavy water and to ensure that costs do not increase faster than the current inflationary trend. (Author)