Experiments of Pool Boiling Performance (Boiling Heat Transfer and Critical Heat Flux) on Designed Micro-Structures

International Nuclear Information System (INIS)

Kim, Seol Ha; Kang, Jun Young; Lee, Gi Chol; Kiyofumia, Moriyama; Kim, Moo Hwan; Park, Hyun Sun

2015-01-01

In general, the evaluation of the boiling performance mainly focuses on two physical parameters: boiling heat transfer (BHT) and critical heat flux (CHF). In the nuclear power plants, both BHT and CHF contribute the nuclear system efficiency and safety, respectively. In this study, BHT and CHF of the pool boiling on well-organized fabricated structured (micro scaled) surface has been evaluated. As a results, BHT change on microstructured surface shows strongly dependent on Pin-fin effect analysis. In terms of CHF, critical size of micro structure for CHF enhancement has been observed and analyzed based on the capillary wicking effect. In this study, BHT and CHF of the pool boiling on well-organized fabricated structured (micro scaled) surface has been evaluated. As a results, BHT change on microstructured surface shows strongly dependent on the roughness ratio. The extended heat transfer area contributes the boiling heat transfer increase on the structured surface, and its quantitative analysis has been performed. In terms of CHF, the critical size of micro structure for CHF enhancement has been observed and analyzed based on the capillary wicking effect. We suggested a capillary limit to CHF delay for modeling capillary induced liquid inflow through microstructured surfaces. The critical size of the capillary limit on the prepared structured surface, determined by a model, could be reasonable explanation points for the experimental results (optimal size for CHF delay). The present experimental results also showed clearly the critical size (10 - 20 μm) for CHF delay, predicted by capillary limit analysis. This study provides fundamental insight into BHT and CHF enhancement of structured surfaces, and an optimal design guide for the required CHF and boiling heat-transfer performance. Finally, this study can contribute the basic understanding of the boiling on designed microstructure surface, and it also suggest the optimal micro scaled structured surface of boiling

Heat and Mass Transport in Heat Pipe Wick Structures

OpenAIRE

Iverson, B. D.; Davis, T. W.; Garimella, S V; North, M. T.; Kang, S.

2007-01-01

Anovel experimental approach is developed for characterizing the performance of heat pipe wick structures. This approach simulates the actual operation of wick structures in a heat pipe. Open, partially submerged, sintered copper wicks of varying pore size are studied under the partially saturated conditions found in normal heat pipe operation. A vertical wick orientation, where the capillary lift is in opposition to gravity, is selected to test the wicks under the most demanding conditions. ...

DC heating induced shape transformation of Ge structures on ultraclean Si(5 5 12) surfaces.

Science.gov (United States)

Dash, J K; Rath, A; Juluri, R R; Raman, P Santhana; Müller, K; Rosenauer, A; Satyam, P V

2011-04-06

We report the growth of Ge nanostructures and microstructures on ultraclean, high vicinal angle silicon surfaces and show that self-assembled growth at optimum thickness of the overlayer leads to interesting shape transformations, namely from nanoparticle to trapezoidal structures, at higher thickness values. Thin films of Ge of varying thickness from 3 to 12 ML were grown under ultrahigh vacuum conditions on a Si(5 5 12) substrate while keeping the substrate at a temperature of 600 °C. The substrate heating was achieved by two methods: (i) by heating a filament under the substrate (radiative heating, RH) and (ii) by passing direct current through the samples in three directions (perpendicular, parallel and at 45° to the (110) direction of the substrate). We find irregular, more spherical-like island structures under RH conditions. The shape transformations have been found under DC heating conditions and for Ge deposition more than 8 ML thick. The longer sides of the trapezoid structures are found to be along (110) irrespective of the DC current direction. We also show the absence of such a shape transformation in the case of Ge deposition on Si(111) substrates. Scanning transmission electron microscopy measurements suggested the mixing of Ge and Si. This has been confirmed with a quantitative estimation of the intermixing using Rutherford backscattering spectrometry (RBS) measurements. The role of DC heating in the formation of aligned structures is discussed. Although the RBS simulations show the presence of a possible SiO(x) layer, under the experimental conditions of the present study, the oxide layer would not play a role in determining the formation of the various structures that were reported here.

Heat transfer characteristics of induced mixed convection

International Nuclear Information System (INIS)

Weiss, Y.; Lahav, C.; Szanto, M.; Shai, I.

1996-01-01

In the present work we focus our attention on the opposed Induced Mixed Convection case, i.e. the flow field structure in a vertical cylinder, closed at its bottom, opens at the top, and being heated circumferentially. The paper reports an experimental study of this complex heat transfer process. For a better understanding of the flow field and the related heat transfer process, two different experimental systems were built. The first was a flow visualization system, with water as the working fluid, while the second system enabled quantitative measurements of the temperature field in air. All the experiments were performed in the turbulent flow regime. In order to learn about all possible flow regimes, the visualization tests were conducted in three different length-to-diameter ratios (1/d=1,5,10). Quantitative measurements of the cylindrical wall temperature, as well as the radial and axial temperature profiles in the flow field, were taken in the air system. Based on the visualization observation and the measured wall temperature profile, it was found that the OIMC can be characterized by three main regimes: a mixing regime at the top, a central turbulent core and a boundary layer type of flow adjacent to the heated wall. (authors)

Finite element calculation of stress induced heating of superconductors

International Nuclear Information System (INIS)

Akin, J.E.; Moazed, A.

1976-01-01

This research is concerned with the calculation of the amount of heat generated due to the development of mechanical stresses in superconducting composites. An emperical equation is used to define the amount of stress-induced heat generation per unit volume. The equation relates the maximum applied stress and the experimental measured hysteresis loop of the composite stress-strain diagram. It is utilized in a finite element program to calculate the total stress-induced heat generation for the superconductor. An example analysis of a solenoid indicates that the stress-induced heating can be of the same order of magnitude as eddy current effects

Heat-stress and light-stress induce different cellular pathologies in the symbiotic dinoflagellate during coral bleaching.

Science.gov (United States)

Downs, C A; McDougall, Kathleen E; Woodley, Cheryl M; Fauth, John E; Richmond, Robert H; Kushmaro, Ariel; Gibb, Stuart W; Loya, Yossi; Ostrander, Gary K; Kramarsky-Winter, Esti

2013-01-01

Coral bleaching is a significant contributor to the worldwide degradation of coral reefs and is indicative of the termination of symbiosis between the coral host and its symbiotic algae (dinoflagellate; Symbiodinium sp. complex), usually by expulsion or xenophagy (symbiophagy) of its dinoflagellates. Herein, we provide evidence that during the earliest stages of environmentally induced bleaching, heat stress and light stress generate distinctly different pathomorphological changes in the chloroplasts, while a combined heat- and light-stress exposure induces both pathomorphologies; suggesting that these stressors act on the dinoflagellate by different mechanisms. Within the first 48 hours of a heat stress (32°C) under low-light conditions, heat stress induced decomposition of thylakoid structures before observation of extensive oxidative damage; thus it is the disorganization of the thylakoids that creates the conditions allowing photo-oxidative-stress. Conversely, during the first 48 hours of a light stress (2007 µmoles m(-2) s(-1) PAR) at 25°C, condensation or fusion of multiple thylakoid lamellae occurred coincidently with levels of oxidative damage products, implying that photo-oxidative stress causes the structural membrane damage within the chloroplasts. Exposure to combined heat- and light-stresses induced both pathomorphologies, confirming that these stressors acted on the dinoflagellate via different mechanisms. Within 72 hours of exposure to heat and/or light stresses, homeostatic processes (e.g., heat-shock protein and anti-oxidant enzyme response) were evident in the remaining intact dinoflagellates, regardless of the initiating stressor. Understanding the sequence of events during bleaching when triggered by different environmental stressors is important for predicting both severity and consequences of coral bleaching.

Heat-stress and light-stress induce different cellular pathologies in the symbiotic dinoflagellate during coral bleaching.

Directory of Open Access Journals (Sweden)

C A Downs

Full Text Available Coral bleaching is a significant contributor to the worldwide degradation of coral reefs and is indicative of the termination of symbiosis between the coral host and its symbiotic algae (dinoflagellate; Symbiodinium sp. complex, usually by expulsion or xenophagy (symbiophagy of its dinoflagellates. Herein, we provide evidence that during the earliest stages of environmentally induced bleaching, heat stress and light stress generate distinctly different pathomorphological changes in the chloroplasts, while a combined heat- and light-stress exposure induces both pathomorphologies; suggesting that these stressors act on the dinoflagellate by different mechanisms. Within the first 48 hours of a heat stress (32°C under low-light conditions, heat stress induced decomposition of thylakoid structures before observation of extensive oxidative damage; thus it is the disorganization of the thylakoids that creates the conditions allowing photo-oxidative-stress. Conversely, during the first 48 hours of a light stress (2007 µmoles m(-2 s(-1 PAR at 25°C, condensation or fusion of multiple thylakoid lamellae occurred coincidently with levels of oxidative damage products, implying that photo-oxidative stress causes the structural membrane damage within the chloroplasts. Exposure to combined heat- and light-stresses induced both pathomorphologies, confirming that these stressors acted on the dinoflagellate via different mechanisms. Within 72 hours of exposure to heat and/or light stresses, homeostatic processes (e.g., heat-shock protein and anti-oxidant enzyme response were evident in the remaining intact dinoflagellates, regardless of the initiating stressor. Understanding the sequence of events during bleaching when triggered by different environmental stressors is important for predicting both severity and consequences of coral bleaching.

Electrokinetically driven continuous-flow enrichment of colloidal particles by Joule heating induced temperature gradient focusing in a convergent-divergent microfluidic structure.

Science.gov (United States)

Zhao, Cunlu; Ge, Zhengwei; Song, Yongxin; Yang, Chun

2017-09-07

Enrichment of colloidal particles in continuous flow has not only numerous applications but also poses a great challenge in controlling physical forces that are required for achieving particle enrichment. Here, we for the first time experimentally demonstrate the electrokinetically-driven continuous-flow enrichment of colloidal particles with Joule heating induced temperature gradient focusing (TGF) in a microfluidic convergent-divergent structure. We consider four mechanisms of particle transport, i.e., advection due to electroosmosis, electrophoresis, dielectrophoresis and, and further clarify their roles in the particle enrichment. It is experimentally determined and numerically verified that the particle thermophoresis plays dominant roles in enrichment of all particle sizes considered in this study and the combined effect of electroosmosis-induced advection and electrophoresis is mainly to transport particles to the zone of enrichment. Specifically, the enrichment of particles is achieved with combined DC and AC voltages rather than a sole DC or AC voltage. A numerical model is formulated with consideration of the abovementioned four mechanisms, and the model can rationalize the experimental observations. Particularly, our analysis of numerical and experimental results indicates that thermophoresis which is usually an overlooked mechanism of material transport is crucial for the successful electrokinetic enrichment of particles with Joule heating induced TGF.

Thermo-structural analysis of the rf-induced pulsed surface heating of the CLIC accelerating structures

CERN Document Server

Huopana, Jouni Juhani

2006-01-01

The CLIC (Compact LInear Collider) is being studied at CERN as a potential multi-TeV e+e- collider. The acceleration of the particles is done by RF (Radio Frequency). The surfaces of the RF (radio frequency) accelerating cavities are exposed to high pulsed RF currents which induce cyclic thermal stresses. These cyclic stresses are crucial for the fatigue lifetime of the cavities. To study the fatigue phenomenon properly the induced stresses must be well known. ANSYS FEM simulations were made to study the thermo-structural behaviour of the CLIC accelerating structure in copper zirconium, bimetallic and diamond coated constructions. The simulations showed the existence of high thermal stresses and low stress level shockwaves. It was also shown that the bimetallic structure increases stress values due to the differences in material properties. Diamond coating was found to reduce the thermal stresses.

Flow-Induced Vibration of Circular Cylindrical Structures

Energy Technology Data Exchange (ETDEWEB)

Chen, Shoei-Sheng [Argonne National Lab. (ANL), Argonne, IL (United States). Components Technology Division

1985-06-01

Flow-induced vibration is a term to denote those phenomena associated with the response of structures placed in or conveying fluid flow. More specifically, the terra covers those cases in which an interaction develops between fluid-dynamic forces and the inertia, damping or elastic forces in the structures. The study of these phenomena draws on three disciplines: (1) structural mechanics, (2) mechanical vibration, and (3) fluid dynamics. The vibration of circular cylinders subject to flow has been known to man since ancient times; the vibration of a wire at its natural frequency in response to vortex shedding was known in ancient Greece as aeolian tones. But systematic studies of the problem were not made until a century ago when Strouhal established the relationship between vortex shedding frequency and flow velocity for a given cylinder diameter. The early research in this area has beer summarized by Zdravkovich (1985) and Goldstein (1965). Flow-induced structural vibration has been experienced in numerous fields, including the aerospace industry, power generation/transmission (turbine blades, heat exchanger tubes, nuclear reactor components), civil engineering (bridges, building, smoke stacks), and undersea technology. The problems have usually been encountered or created accidentally through improper design. In most cases, a structural or mechanical component, designed to meet specific objectives, develops problems when the undesired effects of flow field have not been accounted for in the design. When a flow-induced vibration problem is noted in the design stage, the engineer has different options to eliminate the detrimental vibration. Unfortunately, in many situations, the problems occur after the components are already in operation; the "fix" usually is very costly. Flow-induced vibration comprises complex and diverse phenomena; subcritical vibration of nuclear fuel assemblies, galloping of transmission lines, flutter of pipes conveying fluid, and whirling

Spectroscopic analysis of the role of extractives on heat-induced discoloration of black locust (Robinia pseudoacacia)

Science.gov (United States)

Yao Chen; Yongming Fan; Jianmin Gao; Mandla A. Tshabalala; Nicole M. Stark

2012-01-01

To investigate the role of extractives on heat-induced discoloration of wood, samples of black locust (Robinia pseudoacacia) wood flour were extracted with various solvents prior to heat-treatment. Analysis of their color parameters and chromophoric structures showed that the chroma value of the unextracted sample decreased while that of the...

Flow induced vibration in shell and tube heat exchangers

International Nuclear Information System (INIS)

Soper, B.M.H.

1981-01-01

Assessing heat exchanger designs, from the standpoint of flow induced vibration, is becoming increasingly important as shell side flow velocities are increased in a quest for better thermal performance. This paper reviews the state of the art concerning the main sources of vibration excitation, i.e. vortex shedding resonance, turbulent buffeting, fluidelastic instability and acoustic resonance, as well as the structural dynamics of the tubes. It is concluded that there are many areas which require further investigation but there are sufficient data available at present to design, with reasonable confidence, units that will be free from flow induced vibration. Topics which are considered to be key areas for further work are listed

New insights into heat induced structural changes of pectin methylesterase on fluorescence spectroscopy and molecular modeling basis

Science.gov (United States)

Nistor, Oana Viorela; Stănciuc, Nicoleta; Aprodu, Iuliana; Botez, Elisabeta

2014-07-01

Heat-induced structural changes of Aspergillus oryzae pectin methylesterase (PME) were studied by means of fluorescence spectroscopy and molecular modeling, whereas the functional enzyme stability was monitored by inactivation studies. The fluorescence spectroscopy experiments were performed at two pH value (4.5 and 7.0). At both pH values, the phase diagrams were linear, indicating the presence of two molecular species induced by thermal treatment. A red shift of 7 nm was observed at neutral pH by increasing temperature up to 60 °C, followed by a blue shift of 4 nm at 70 °C, suggesting significant conformational rearrangements. The quenching experiments using acrylamide and iodide demonstrate a more flexible conformation of enzyme with increasing temperature, especially at neutral pH. The experimental results were complemented with atomic level observations on PME model behavior after performing molecular dynamics simulations at different temperatures. The inactivation kinetics of PME in buffer solutions was fitted using a first-order kinetics model, resulting in activation energy of 241.4 ± 7.51 kJ mol-1.

Denatured states of yeast cytochrome c induced by heat and guanidinium chloride are structurally and thermodynamically different.

Science.gov (United States)

Zaidi, Sobia; Haque, Md Anzarul; Ubaid-Ullah, Shah; Prakash, Amresh; Hassan, Md Imtaiyaz; Islam, Asimul; Batra, Janendra K; Ahmad, Faizan

2017-05-01

A sequence alignment of mammalian cytochromes c with yeast iso-1-cytochrome c (y-cyt-c) shows that the yeast protein contains five extra N-terminal residues. We have been interested in understanding the question: What is the role of these five extra N-terminal residues in folding and stability of the protein? To answer this question we have prepared five deletants of y-cyt-c by sequentially removing these extra residues. During our studies on the wild type (WT) protein and its deletants, we observed that the amount of secondary structure in the guanidinium chloride (GdmCl)-induced denatured (D) state of each protein is different from that of the heat-induced denatured (H) state. This finding is confirmed by the observation of an additional cooperative transition curve of optical properties between H and D states on the addition of different concentrations of GdmCl to the already heat denatured WT y-cyt-c and its deletants at pH 6.0 and 68°C. For each protein, analysis of transition curves representing processes, native (N) state ↔ D state, N state ↔ H state, and H state ↔ D state, was done to obtain Gibbs free energy changes associated with all the three processes. This analysis showed that, for each protein, thermodynamic cycle accommodates Gibbs free energies associated with transitions between N and D states, N and H states, and H and D states, the characteristics required for a thermodynamic function. All these experimental observations have been supported by our molecular dynamics simulation studies.

Structural morphology of acoustically levitated and heated nanosilica droplet

International Nuclear Information System (INIS)

Kumar, Ranganathan; Tijerino, Erick; Saha, Abhishek; Basu, Saptarshi

2010-01-01

We study the vaporization and precipitation dynamics of a nanosilica encapsulated water droplet by levitating it acoustically and heating it with a CO 2 laser. For all concentrations, we observe three phases: solvent evaporation, surface agglomeration, and precipitation leading to bowl or ring shaped structures. At higher concentrations, ring reorientation and rotation are seen consistently. The surface temperature from an infrared camera is seen to be dependent on the final geometrical shape of the droplet and its rotation induced by the acoustic field of the levitator. With nonuniform particle distribution, these structures can experience rupture which modifies the droplet rotational speed.

Furan: A critical heat induced dietary contaminant

DEFF Research Database (Denmark)

Mariotti, María S.; Granby, Kit; Rozowski, Jaime

2013-01-01

The presence of furan in a broad range of heat processed foods (0-6000 μg kg-1) has received considerable attention due to the fact that this heat induced contaminant is considered as a "possible carcinogenic compound to humans". Since a genotoxic mode of action could be associated with furan...... of some critical factors such as heating conditions, pH and matrix microstructure are discussed in order to propose some potential methodologies for furan mitigation in a wide range of heated foods. © 2013 The Royal Society of Chemistry....

Magnetic induced heating of nanoparticle solutions

Energy Technology Data Exchange (ETDEWEB)

Murph, S. Hunyadi [Savannah River Site (SRS), Aiken, SC (United States); Univ. of Georgia, Athens, GA (United States); Brown, M. [Savannah River Site (SRS), Aiken, SC (United States); Coopersmith, K. [Savannah River Site (SRS), Aiken, SC (United States); Fulmer, S. [Savannah River Site (SRS), Aiken, SC (United States); Sessions, H. [Savannah River Site (SRS), Aiken, SC (United States); Ali, M. [Univ. of South Carolina, Columbia, SC (United States)

2016-12-02

Magnetic induced heating of nanoparticles (NP) provides a useful advantage for many energy transfer applications. This study aims to gain an understanding of the key parameters responsible for maximizing the energy transfer leading to nanoparticle heating through the use of simulations and experimental results. It was found that magnetic field strength, NP concentration, NP composition, and coil size can be controlled to generate accurate temperature profiles in NP aqueous solutions.

46 CFR 154.178 - Contiguous hull structure: Heating system.

Science.gov (United States)

2010-10-01

... 46 Shipping 5 2010-10-01 2010-10-01 false Contiguous hull structure: Heating system. 154.178... Equipment Hull Structure § 154.178 Contiguous hull structure: Heating system. The heating system for transverse and longitudinal contiguous hull structure must: (a) Be shown by a heat load calculation to have...

Heat stroke induced cerebellar dysfunction: A “forgotten syndrome”

Science.gov (United States)

Kosgallana, Athula D; Mallik, Shreyashee; Patel, Vishal; Beran, Roy G

2013-01-01

We report a case of heat stroke induced acute cerebellar dysfunction, a rare neurological disease characterized by gross cerebellar dysfunction with no acute radiographic changes, in a 61 years old ship captain presenting with slurred speech and gait ataxia. A systematic review of the literature on heat stroke induced cerebellar dysfunction was performed, with a focus on investigations, treatment and outcomes. After review of the literature and detailed patient investigation it was concluded that this patient suffered heat stroke at a temperature less than that quoted in the literature. PMID:24340279

Heat-induced alterations in the cell nucleus

International Nuclear Information System (INIS)

Kampinga, H.H.

1989-01-01

Hyperthermia may kill eukaryotic cells and may also enhance the radiosensitivity of those cells that survive the heat treatment. Clinically, the possible use of hyperthermia as an adjuvant in the radiotherapeutic treatment of cancer needs the understanding of mechanisms that underlay heat-induced cell death and radiosensitization. By in vitro heating of established human (HeLaS3) and rodent (Ehrlich Ascites Tumor and LM fibroblast) cell lines, both killing and radiosensitization were investigated. (author). 1067 refs.; 76 figs.; 19 tabs

Heat transfer characteristics and limitations analysis of heat-pipe-cooled thermal protection structure

International Nuclear Information System (INIS)

Guangming, Xiao; Yanxia, Du; Yewei, Gui; Lei, Liu; Xiaofeng, Yang; Dong, Wei

2014-01-01

The theories of heat transfer, thermodynamics and fluid dynamics are employed to develop the coupled heat transfer analytical methods for the heat-pipe-cooled thermal protection structure (HPC TPS), and a three-dimensional numerical method considering the sonic limit of heat pipe is proposed. To verify the calculation correctness, computations are carried out for a typical heat pipe and the results agree well with experimental data. Then, the heat transfer characteristics and limitations of HPC TPS are mainly studied. The studies indicate that the use of heat pipe can reduce the temperature at high heat flux region of structure efficiently. However, there is a frozen startup period before the heat pipe reaching a steady operating state, and the sonic limit will be a restriction on the heat transfer capability. Thus, the effects of frozen startup must be considered for the design of HPC TPS. The simulation model and numerical method proposed in this paper can predict the heat transfer characteristics of HPC TPS quickly and exactly, and the results will provide important references for the design or performance evaluation of HPC TPS. - Highlights: • Numerical methods for the heat-pipe-cooled thermal protection structure are studied. • Three-dimensional simulation model considering sonic limit of heat pipe is proposed. • The frozen startup process of the embedded heat pipe can be predicted exactly. • Heat transfer characteristics of TPS and limitations of heat pipe are discussed

Heat-induced reorganization of the structure of photosystem II membranes: role of oxygen evolving complex.

Science.gov (United States)

Busheva, Mira; Tzonova, Iren; Stoitchkova, Katerina; Andreeva, Atanaska

2012-12-05

The sensitivity of the green plants' photosystem II (PSII) to high temperatures is investigated in PSII enriched membranes and in membranes, from which the oxygen evolving complex is removed. Using steady-state 77 K fluorescence and resonance Raman spectroscopy we analyze the interdependency between the temperature-driven changes in structure and energy distribution in the PSII supercomplex. The results show that the heat treatment induces different reduction of the 77 K fluorescence emission in both types of investigated membranes: (i) an additional considerable decrease of the overall fluorescence emission in Tris-washed membranes as compared to the native membranes; (ii) a transition point at 42°C(,) observed only in native membranes; (iii) a sharp reduction of the PSII core fluorescence in Tris-washed membranes at temperatures higher than 50°C; (iv) a 3 nm red-shift of F700 band's maximum in Tris-washed membranes already at 20°C and its further shift by 1 nm at temperature increase. Both treatments intensified their action by increasing the aggregation and dissociation of the peripheral light harvesting complexes. The oxygen-evolving complex, in addition to its main function to produce O(2), increases the thermal stability of PSII core by strengthening the connection between the core and the peripheral antenna proteins and by keeping their structural integrity. Copyright © 2012 Elsevier B.V. All rights reserved.

Structural changes in deashed coals induced by heat treatment; Kanetsu shori ni yoru dakkaitan no kozo henka

Energy Technology Data Exchange (ETDEWEB)

Sugano, M.; Sekita, M.; Muramatsu, Y.; Mashimo, K.; Wainai, T. [Nihon University, Tokyo (Japan). College of Science and Technology

1996-10-28

Change in structures of 3 kinds of coals with different coal ranks and their deashed coals was studied by heat treatment below 200{degree}C. In experiment, crushed Adaro, Taiheiyo and Huaibei coals below 200mesh and their deashed coals were used as specimens. The coal and deashed coal specimens dried in vacuum at 110{degree}C for 3 hours were filled into an autoclave, and the heat-treated coal specimens were prepared by holding them under initial nitrogen pressure of 2kg/cm{sup 2} at a fixed temperature for 30min. Extraction using pyridine as solvent, volumetric swelling using methanol or benzene as solvent, and measurement of the amount of carboxyl and phenolic hydroxyl functional groups were conducted for these coal specimens. The experimental results are as follows. Huaibei coal has developed aromatic ring structure, and its structure is hardly affected by heat treatment. The oxygen containing functional groups decrease by heat treatment over 100{degree}C in Adaro coal and 150{degree}C in Taiheiyo coal, and PS, MQ and BQ also decrease due to aggregation between molecules. 5 refs., 2 figs.

Sex specific effects of heat induced hormesis in Hsf-deficient Drosophila melanogaster

DEFF Research Database (Denmark)

Sørensen, J G; Kristensen, Torsten Nygård; Kristensen, K V

2007-01-01

In insects mild heat stress early in life has been reported to increase life span and heat resistance later in life, a phenomenon termed hormesis. Here, we test if the induction of the heat shock response by mild heat stress is mediating hormesis in longevity and heat resistance at older age...... line, seemingly mediated by the production of heat shock proteins (Hsps). The results indicate that heat inducible Hsps are important for heat induced hormesis in longevity and heat stress resistance. However, the results also suggest that other processes are involved and that different mechanisms...... might have marked sex specific impact...

Considerations on heat deposition by eddy currents in the cold structure of INTOR/NET

International Nuclear Information System (INIS)

Bloemer, B.; Farfaletti-Casali, F.

1983-01-01

In a tokamak like INTOR/NET large eddy currents can be induced in all conductive parts of the reactor mainly by the time-varying poloidal fields. In order to minimize the refrigeration power the heat load generated by eddy currents has to be kept as small as possibly especially in the large toroidal- and poloidal-field coil support structures, which are conductive and at temperatures of less than 4.2 K. A method is described identifying the parts of the structure wherein most of the heat generated by eddy currents is dissipated. By dividing a given configuration into reasonable segments of appointed geometry eddy current losses can easily be calculated. Compared to sophisticated computer programs this procedure is simple but of sufficient accuracy for a lot of applications and it delivers prompt results. The method is applied to the TF coil support structure of a specific design of INTOR/NET. As the results show that the heat load is intolerably high a modified design is proposed. (author)

Induced current heating probe

International Nuclear Information System (INIS)

Thatcher, G.; Ferguson, B.G.; Winstanley, J.P.

1984-01-01

An induced current heating probe is of thimble form and has an outer conducting sheath and a water flooded flux-generating unit formed from a stack of ferrite rings coaxially disposed in the sheath. The energising coil is made of solid wire which connects at one end with a coaxial water current tube and at the other end with the sheath. The stack of ferrite rings may include non-magnetic insulating rings which help to shape the flux. (author)

Theoretical analysis of the mode coupling induced by heat of large-pitch micro-structured fibers

International Nuclear Information System (INIS)

Zhang Hai-Tao; Hao Jie; Yan Ping; Gong Ma-Li; Chen Dan

2015-01-01

In this paper, a theoretical model to analyze the mode coupling induced by heat, when the fiber amplifier works at high power configuration, is proposed. The model mainly takes into consideration the mode field change due to the thermally induced refractive index change and the coupling between modes. A method to predict the largest average output power of fiber is also proposed according to the mode coupling theory. The largest average output power of a large pitch fiber with a core diameter of 190 μm and an available pulse energy of 100 mJ is predicted to be 540 W, which is the highest in large mode field fibers. (paper)

Microstructural transformation with heat-treatment of aluminum hydroxide with gibbsite structure

International Nuclear Information System (INIS)

Mitsui, Tomohiro; Matsui, Toshiaki; Eguchi, Koichi; Kikuchi, Ryuji

2009-01-01

Aluminum hydroxide with gibbsite structure was prepared, and the microstructural transformation of the sample heat-treated at various temperatures was investigated. The sample was characterized by field emission scanning electron microscopy (FE-SEM), X-ray diffraction (XRD), thermogravimetry and differential thermal analysis (TG-DTA), and BET surface area. The shape of the grains in the prepared sample was hexagonal prism-like morphology. The prepared sample kept a metastable state of alumina phase at higher temperatures than the commercially available gibbsite powders. The prepared gibbsite grains underwent characteristic structural change depending on the calcination temperature. The transformation of the surface morphology was initiated at 400degC, leading to the formation of cracks with the direction parallel to the basal plane. After calcination at 1200degC, a large number of grooves were formed on the surface of the lateral planes. The specific structural change of gibbsite induced by the heat treatment was strongly related to the topotactic dehydration from gibbsite and subsequent phase transition to aluminum oxides. (author)

Chaos of radiative heat-loss-induced flame front instability.

Science.gov (United States)

Kinugawa, Hikaru; Ueda, Kazuhiro; Gotoda, Hiroshi

2016-03-01

We are intensively studying the chaos via the period-doubling bifurcation cascade in radiative heat-loss-induced flame front instability by analytical methods based on dynamical systems theory and complex networks. Significant changes in flame front dynamics in the chaotic region, which cannot be seen in the bifurcation diagrams, were successfully extracted from recurrence quantification analysis and nonlinear forecasting and from the network entropy. The temporal dynamics of the fuel concentration in the well-developed chaotic region is much more complicated than that of the flame front temperature. It exhibits self-affinity as a result of the scale-free structure in the constructed visibility graph.

Diffusion induced by cyclotron resonance heating

International Nuclear Information System (INIS)

Riyopoulos, S.; Tajima, T.; Hatori, T.; Pfirsch, D.

1985-09-01

The wave induced particle transport during the ion cyclotron resonance heating is studied in collisionless toroidal plasmas. It is shown that the previously neglected non-conservation of the toroidal angular momentum IP/sub phi/ caused by the toroidal wave component E/sub phi/ is necessary to allow particle diffusion and yields the leading diffusive contribution. While the induced ion transport for the rf power in contemporary experiments is of the order of the neoclassical value, that of fast alpha particles is quite large if resonance is present

Biophoton emission induced by heat shock.

Directory of Open Access Journals (Sweden)

Katsuhiro Kobayashi

Full Text Available Ultraweak biophoton emission originates from the generation of reactive oxygen species (ROS that are produced in mitochondria as by-products of cellular respiration. In healthy cells, the concentration of ROS is minimized by a system of biological antioxidants. However, heat shock changes the equilibrium between oxidative stress and antioxidant activity, that is, a rapid rise in temperature induces biophoton emission from ROS. Although the rate and intensity of biophoton emission was observed to increase in response to elevated temperatures, pretreatment at lower high temperatures inhibited photon emission at higher temperatures. Biophoton measurements are useful for observing and evaluating heat shock.

Mechanical analysis of a heat-shock induced developmental defect

Science.gov (United States)

Crews, Sarah M.; McCleery, W. Tyler; Hutson, M. Shane

2014-03-01

Embryonic development in Drosophila is a complex process involving coordinated movements of mechanically interacting tissues. Perturbing this system with a transient heat shock can result in a number of developmental defects. In particular, a heat shock applied during the earliest morphogenetic movements of gastrulation can lead to apparent recovery, but then subsequent morphogenetic failure 5-6 hours later during germ band retraction. The process of germ band retraction requires an intact amnioserosa - a single layered extra-embryonic epithelial tissue - and heat shock at gastrulation can induce the later opening of holes in the amnioserosa. These holes are highly correlated with failures of germ band retraction. These holes could be caused by a combination of mechanical weakness in the amnioserosa or local increases in mechanical stress. Here, we assess the role of mechanical stress using confocal imaging to compare cell and tissue morphology in the amnioserosa of normal and heat-shocked embryos and laser hole drilling to map the stress field around the times and locations at which heat-shock induced holes open.

Exercise-induced heat stress disrupts the shear-dilatory relationship.

Science.gov (United States)

Ives, Stephen J; Lefferts, Wesley K; Wharton, Margret; Fehling, Patricia C; Smith, Denise L

2016-12-01

What is the central question of this study? Although heat stress is known to increase cardiovascular strain, no study, to date, had explored the potential impact of exercise-induced heat stress on vascular function. What is the main finding and its importance? We found that acute exercise tended to reduce flow-mediated dilatation (FMD), owing in part to reduced reactive hyperaemia/shear stimulus; thus, when FMD is normalized to shear no postexercise deficit exists. Exercise-induced heat stress increased reactive hyperaemia, shear rate, coupled with a sustained FMD postexercise, suggests that exercise-induced heat stress increases the amount of shear stimulus to elicit a similar response, indicating reduced vascular responsiveness, or reserve, which might increase cardiovascular susceptibility. Heat stress increases cardiovascular strain and is of particular concern in occupations, such as firefighting, in which individuals are required to perform strenuous work while wearing personal protective equipment. Sudden cardiac events are associated with strenuous activity and are the leading cause of duty-related death among firefighters, accounting for ∼50% of duty-related fatalities per year. Understanding the acute effects of exercise-induced heat stress (EIHS) on vascular endothelial function may provide insight into the mechanisms precipitating acute coronary events in firefighters. The purpose of this study, therefore, was to determine the effects of EIHS on vascular endothelial function. Using a balanced crossover design, 12 healthy men performed 100 min of moderate-intensity, intermittent exercise with and without EIHS (personal protective equipment or cooling vest, respectively). Measurements of flow-mediated dilatation (FMD), reactive hyperaemia and shear rate area under the curve (SR AUC ) were performed pre- and postexercise. During EIHS, core temperature was significantly higher (38 ± 0.1 versus 37 ± 0.1°C). Postexercise FMD tended to be suppressed

An improved model of heat-induced hyperalgesia--repetitive phasic heat pain causing primary hyperalgesia to heat and secondary hyperalgesia to pinprick and light touch.

Science.gov (United States)

Jürgens, Tim P; Sawatzki, Alexander; Henrich, Florian; Magerl, Walter; May, Arne

2014-01-01

This study tested a modified experimental model of heat-induced hyperalgesia, which improves the efficacy to induce primary and secondary hyperalgesia and the efficacy-to-safety ratio reducing the risk of tissue damage seen in other heat pain models. Quantitative sensory testing was done in eighteen healthy volunteers before and after repetitive heat pain stimuli (60 stimuli of 48°C for 6 s) to assess the impact of repetitive heat on somatosensory function in conditioned skin (primary hyperalgesia area) and in adjacent skin (secondary hyperalgesia area) as compared to an unconditioned mirror image control site. Additionally, areas of flare and secondary hyperalgesia were mapped, and time course of hyperalgesia determined. After repetitive heat pain conditioning we found significant primary hyperalgesia to heat, and primary and secondary hyperalgesia to pinprick and to light touch (dynamic mechanical allodynia). Acetaminophen (800 mg) reduced pain to heat or pinpricks only marginally by 11% and 8%, respectively (n.s.), and had no effect on heat hyperalgesia. In contrast, the areas of flare (-31%) and in particular of secondary hyperalgesia (-59%) as well as the magnitude of hyperalgesia (-59%) were significantly reduced (all pheat pain induces significant peripheral sensitization (primary hyperalgesia to heat) and central sensitization (punctate hyperalgesia and dynamic mechanical allodynia). These findings are relevant to further studies using this model of experimental heat pain as it combines pronounced peripheral and central sensitization, which makes a convenient model for combined pharmacological testing of analgesia and anti-hyperalgesia mechanisms related to thermal and mechanical input.

An Improved Model of Heat-Induced Hyperalgesia—Repetitive Phasic Heat Pain Causing Primary Hyperalgesia to Heat and Secondary Hyperalgesia to Pinprick and Light Touch

Science.gov (United States)

Henrich, Florian; Magerl, Walter; May, Arne

2014-01-01

This study tested a modified experimental model of heat-induced hyperalgesia, which improves the efficacy to induce primary and secondary hyperalgesia and the efficacy-to-safety ratio reducing the risk of tissue damage seen in other heat pain models. Quantitative sensory testing was done in eighteen healthy volunteers before and after repetitive heat pain stimuli (60 stimuli of 48°C for 6 s) to assess the impact of repetitive heat on somatosensory function in conditioned skin (primary hyperalgesia area) and in adjacent skin (secondary hyperalgesia area) as compared to an unconditioned mirror image control site. Additionally, areas of flare and secondary hyperalgesia were mapped, and time course of hyperalgesia determined. After repetitive heat pain conditioning we found significant primary hyperalgesia to heat, and primary and secondary hyperalgesia to pinprick and to light touch (dynamic mechanical allodynia). Acetaminophen (800 mg) reduced pain to heat or pinpricks only marginally by 11% and 8%, respectively (n.s.), and had no effect on heat hyperalgesia. In contrast, the areas of flare (−31%) and in particular of secondary hyperalgesia (−59%) as well as the magnitude of hyperalgesia (−59%) were significantly reduced (all pheat pain induces significant peripheral sensitization (primary hyperalgesia to heat) and central sensitization (punctate hyperalgesia and dynamic mechanical allodynia). These findings are relevant to further studies using this model of experimental heat pain as it combines pronounced peripheral and central sensitization, which makes a convenient model for combined pharmacological testing of analgesia and anti-hyperalgesia mechanisms related to thermal and mechanical input. PMID:24911787

Analysis of the flow structure and heat transfer in a vertical mantle heat exchanger

DEFF Research Database (Denmark)

Knudsen, Søren; Morrison, GL; Behnia, M

2005-01-01

initially mixed and initially stratified inner tank and mantle. The analysis of the heat transfer showed that the flow in the mantle near the inlet is mixed convection flow and that the heat transfer is dependent on the mantle inlet temperature relative to the core tank temperature at the mantle level. (C......The flow structure inside the inner tank and inside the mantle of a vertical mantle heat exchanger was investigated using a full-scale tank designed to facilitate flow visualisation. The flow structure and velocities in the inner tank and in the mantle were measured using a Particle Image...... Velocimetry (PIV) system. A Computational Fluid Dynamics (CFD) model of the vertical mantle heat exchanger was also developed for a detailed evaluation of the heat flux at the mantle wall and at the tank wall. The flow structure was evaluated for both high and low temperature incoming flows and for both...

Mesoscale Eddies in the Northwestern Pacific Ocean: Three-Dimensional Eddy Structures and Heat/Salt Transports

Science.gov (United States)

Dong, Di; Brandt, Peter; Chang, Ping; Schütte, Florian; Yang, Xiaofeng; Yan, Jinhui; Zeng, Jisheng

2017-12-01

The region encompassing the Kuroshio Extension (KE) in the Northwestern Pacific Ocean (25°N-45°N and 130°E-180°E) is one of the most eddy-energetic regions of the global ocean. The three-dimensional structures and transports of mesoscale eddies in this region are comprehensively investigated by combined use of satellite data and Argo profiles. With the allocation of Argo profiles inside detected eddies, the spatial variations of structures of eddy temperature and salinity anomalies are analyzed. The results show that eddies predominantly have subsurface (near-surface) intensified temperature and salinity anomalies south (north) of the KE jet, which is related to different background stratifications between these regions. A new method based on eddy trajectories and the inferred three-dimensional eddy structures is proposed to estimate heat and salt transports by eddy movements in a Lagrangian framework. Spatial distributions of eddy transports are presented over the vicinity of the KE for the first time. The magnitude of eddy-induced meridional heat (freshwater volume) transport is on the order of 0.01 PW (103 m3/s). The eddy heat transport divergence results in an oceanic heat loss south and heat gain north of the KE, thereby reinforcing and counteracting the oceanic heat loss from air-sea fluxes south and north of the KE jet, respectively. It also suggests a poleward heat transport across the KE jet due to eddy propagation.

Multifunctional Hot Structure Heat Shield

Data.gov (United States)

National Aeronautics and Space Administration — This project is performing preliminary development of a Multifunctional Hot Structure (HOST) heat shield for planetary entry. Results of this development will...

Heat transfer enhancement by finned heat sinks with micro-structured roughness

International Nuclear Information System (INIS)

Ventola, L; Chiavazzo, E; Asinari, P; Calignano, F; Manfredi, D

2014-01-01

We investigated the benefits of micro-structured roughness on heat transfer performance of heat sinks, cooled by forced air. Heat sinks in aluminum alloy by direct metal laser sintering (DMLS) manufacturing technique were fabricated; values of the average surface roughness R a from 1 to 25 microns (standard milling leads to roughness around 1 micron) under turbulent regimes (Reynolds number based on heating edge from 3000 to 17000) have been explored. An enhancement of 50% in thermal performances with regards to standard manufacturing was observed. This may open the way for huge boost in the technology of electronic cooling by DMLS.

Heat Transfer Enhancement by Finned Heat Sinks with Micro-structured Roughness

Science.gov (United States)

Ventola, L.; Chiavazzo, E.; Calignano, F.; Manfredi, D.; Asinari, P.

2014-04-01

We investigated the benefits of micro-structured roughness on heat transfer performance of heat sinks, cooled by forced air. Heat sinks in aluminum alloy by direct metal laser sintering (DMLS) manufacturing technique were fabricated; values of the average surface roughness Ra from 1 to 25 microns (standard milling leads to roughness around 1 micron) under turbulent regimes (Reynolds number based on heating edge from 3000 to 17000) have been explored. An enhancement of 50% in thermal performances with regards to standard manufacturing was observed. This may open the way for huge boost in the technology of electronic cooling by DMLS.

[Suppressive Effects of Extract of Cedar Wood on Heat-induced Expression of Cellular Heat Shock Protein].

Science.gov (United States)

Miyakoshi, Junji; Matsubara, Eri; Narita, Eijiro; Koyama, Shin; Shimizu, Yoko; Kawai, Shuichi

2018-01-01

 In recent years, highly antimicrobial properties of cedar heartwood essential oil against the wood-rotting fungi and pathogenic fungi have been reported in several papers. Antimicrobial properties against oral bacteria by hinokitiol contained in Thujopsis have been also extensively studied. The relation of naturally derived components and human immune system has been studied in some previous papers. In the present study, we focused on Japanese cedar, which has the widest artificial afforestation site in the country among various tree species. Extract oil was obtained from mixture of sapwood and heartwood of about 40-year cedar grown in Oguni, Kumamoto, Japan. We examined the influence of extract components from Japanese cedar woods on the expression of heat shock protein 70 (Hsp70) during heating, and on the micronucleus formation induced by the treatment of bleomycin as a DNA damaging agent. Cell lines used in this study were human fetal glial cells (SVGp12) and human glioma cells (MO54). Remarkable suppression of the Hsp70 expression induced by heating at 43°C was detected by the treatment of cedar extract in both SVGp12 and MO54 cells. We also found that cedar extract had an inhibitory tendency to reduce the micronucleus formation induced by bleomycin. From these results, the extract components from Japanese cedar woods would have an inhibitory effect of the stress response as a suppression of the heat-induced Hsp70 expression, and might have a reductive effect on carcinogenicity.

Racemization of Valine by Impact-Induced Heating

Science.gov (United States)

Furukawa, Yoshihiro; Takase, Atsushi; Sekine, Toshimori; Kakegawa, Takeshi; Kobayashi, Takamichi

2018-03-01

Homochirality plays an important role in all living organisms but its origin remains unclear. It also remains unclear whether such chiral molecules survived terrestrial heavy impact events. Impacts of extraterrestrial objects on early oceans were frequent and could have affected the chirality of oceanic amino acids when such amino acids accumulated during impacts. This study investigated the effects of shock-induced heating on enantiomeric change of valine with minerals such as olivine ([Mg0.9, Fe0.1]2SiO4), hematite (Fe2O3), and calcite (CaCO3). With a shock wave generated by an impact at 0.8 km/s, both d- and l-enriched valine were significantly decomposed and partially racemized under all experimental conditions. Different minerals had different shock impedances; therefore, they provided different P-T conditions for identical impacts. Furthermore, the high pH of calcite promoted the racemization of valine. The results indicate that in natural hypervelocity impacts, amino acids in shocked oceanic water would have decomposed completely, since impact velocity and the duration of shock compression and heating are typically greater in hypervelocity impact events than those in experiments. Even with the shock wave by the impact of small and decelerated projectiles in which amino acids survive, the shock heating may generate sufficient heat for significant racemization in shocked oceanic water. However, the duration of shock induced heating by small projectiles is limited and the population of such decelerated projectiles would be limited. Therefore, even though impacts of asteroids and meteorites were frequent on the prebiotic Earth, impact events would not have significantly changed the ee of proteinogenic amino acids accumulated in the entire ocean.

The stress characteristics of plate-fin structures at the different operation parameters of LNG heat exchanger

Directory of Open Access Journals (Sweden)

Ma Hongqiang

2018-01-01

Full Text Available In this paper, the stresses of plate-fin structures at the different operation parameters were analyzed in actual operation process of LNG plate-fin heat exchanger based on finite element method and thermal elastic theory. Stress characteristics of plate-fin structures were investigated at the different operation parameters of that. The results show that the structural failure of plate-fin structures is mainly induced by the maximum shear stress at the brazing filler metal layer between plate and fin while by the maximum normal stress in the region of brazed joint near the fin side. And a crack would initiate in brazed joint near the fin side. The maximum normal stress is also main factor to result in the structural failure of plate-fin structures at the different temperature difference (between Natural Gas (NG and Mixture Refrigerant (MR, MR temperature and NG pressure of LNG heat exchanger. At the same time, the peak stresses obviously increase as the temperature difference, MR temperature and NG pressure increase. These results will provide some constructive instructions in the safe operation of LNG plate-fin heat exchanger in a large-scale LNG cold-box.

First-principles assessment of potential ultrafast laser-induced structural transition in Ni

Energy Technology Data Exchange (ETDEWEB)

Bévillon, E.; Colombier, J.P., E-mail: jean.philippe.colombier@univ-st-etienne.fr; Stoian, R.

2016-06-30

Highlights: • First-principles theory calculations in nonequilibrium conditions. • Electronic temperatures fully and consistently taken into account. • Evaluation of an ultrafast laser-induced solid-to-solid transition in Ni. • Relative energies, phonon spectra and energy path are evaluated. • Discussion on the generation of non-thermal forces in metals. - Abstract: The possibility to trigger ultrafast solid-to-solid transitions in transition metals under femtosecond laser irradiation is investigated by means of first-principles calculations. Electronic heating can drastically modify screening, charge distribution and atomic binding features, potentially determining new structural relaxation paths in the solid phase, before thermodynamic solid-to-liquid transformations set in. Consequently, we evaluate here the effect of electronic excitation on structural stability and conditions for structural transitions. Ni is chosen as a case study for the probability of a solid transition, and the stability of its FCC phase is compared to the non-standard HCP structure while accounting for the heating of the electronic subsystem. From a phonon spectra analysis, we show that the thermodynamic stability order reverses at an electronic temperature of around 10{sup 4} K. Both structures exhibit a dynamic stability, indicating they present a metastability depending on the heating. However, the general hardening of phonon modes with the increase of the electronic temperature points out that no transformation will occur, as confirmed by the study of a typical FCC to HCP diffusionless transformation path, showing an increasing energy barrier. Finally, based on electronic density of states interpretation, the tendency of different metal categories to undergo or not an ultrafast laser-induced structural transition is discussed.

Tempo enhances heat-induced apoptosis by mitochondrial targeting of Bax

International Nuclear Information System (INIS)

Zhao, Q.-L.; Fujiwara, Y.; Kondo, T.

2003-01-01

A stable membrane-permeable nitroxide, Tempo, exerts an SOD-like antioxidant activity against ROS. Reportedly, Tempo inhibits ROS-induced thymocyte apoptosis, while 10 mM Tempo activates JNK1 to induce apoptosis in breast cancer cells. We have observed that nontoxic 5 mM Tempo enhances suboptimal hyperthermia (44 deg C/10 min)-induced apoptosis in U937 cells. Here we report the enhancing mechanism, focusing on activation and targeting of Bax to mitochondria and cytochrome c release. Methods: U937 cells were treated with either Tempo (5 mM, 37 deg C/10 min), heating (44 deg C/10 min), or Tempo-plus-heating, washed and incubated for various times up to 6 h, until assessing apoptosis, mitochondrial potential (ΔΨ>), and amount of superoxide by flow cytometry using Annexin V-FITC/PI, TMRM, and dihydroethidium, respectively. Bax, Bcl-2 and Bcl-XL, and cytochrome c were detected by western blotting, activated Bax was by immunoprecipitation, and ATP was by a luciferase assay. Bax targeting to and cytochrome c release from mitochorndria were also detected immunocytochemically under fluorescent microscopy. Results and Discussion: Treatment of U937 cells with 5 mM Tempo for 10 min at 37 deg C or suboptimal heating (44 deg C/ 10 min) alone did not induce apoptosis. The combined treatment with 5 mM Tempo and 44 deg C for 10 min dramatically induced ∼90% apoptosis in 6 h, as did the 44 deg C/30 min heating. During the enhanced apoptosis, cytochrome c release progressed. Although signals of Bcl-2, Bcl-XL and Bax in cell lysates were not altered, Bax was specifically activated and translocated to mitochondria after the combined treatment. Further, loss of ΔΨ>and decreases in superoxide and ATP progressed after the combined treatment, suggesting that the treatment may disturb mitochondrial electron transport. Thus, Tempo sensitizes the heat-induced apoptosis through (1) targeting of Bax to mitochondria and releasing cytochrome c, and (2) mitochondrial dysfunction

Heating induced structural and chemical behavior of KD2PO4 in the 25 °C–215 °C temperature range

International Nuclear Information System (INIS)

Botez, Cristian E.; Morris, Joshua L.; Encerrado Manriquez, Andres J.; Anchondo, Adan

2013-01-01

We have used powder x-ray diffraction (XRD) to investigate the structural and chemical modifications undergone by KD 2 PO 4 (DKDP) upon heating from room temperature to 215 °C. Full-profile (Le Bail) analysis of our temperature-resolved data shows no evidence of polymorphic structural transitions or deuterium–hydrogen isotope exchange occurring below T s = 185 °C. The lattice parameters of DKDP vary smoothly upon heating to T s and are 0.2% to 0.6% greater than those of its isostructural hydrogenated counterpart KH 2 PO 4 (KDP). In addition, XRD isotherms collected at T s demonstrate the structural and chemical stability of the title compound at this temperature over a 10.5 h time period. Upon further heating, however, the tetragonal DKDP phase becomes unstable, as evidenced by its transition to a monoclinic DKDP modification and eventual chemical decomposition via dehydration. - Highlights: • Structural and chemical behavior of KD 2 PO 4 is investigated upon heating to 215 °C • No polymorphic transitions or deuterium-hydrogen isotope exchange below T s = 185 °C • KD 2 PO 4 is structurally and chemically stable at T s over a 10.5 h time period • KD 2 PO 4 chemically decomposes via dehydration upon heating above T d = 195 °C

Heat Removal from Bipolar Transistor by Loop Heat Pipe with Nickel and Copper Porous Structures

Science.gov (United States)

Smitka, Martin; Malcho, Milan

2014-01-01

Loop heat pipes (LHPs) are used in many branches of industry, mainly for cooling of electrical elements and systems. The loop heat pipe is a vapour-liquid phase-change device that transfers heat from evaporator to condenser. One of the most important parts of the LHP is the porous wick structure. The wick structure provides capillary force to circulate the working fluid. To achieve good thermal performance of LHP, capillary wicks with high permeability and porosity and fine pore radius are expected. The aim of this work was to develop porous structures from copper and nickel powder with different grain sizes. For experiment copper powder with grain size of 50 and 100 μm and nickel powder with grain size of 10 and 25 μm were used. Analysis of these porous structures and LHP design are described in the paper. And the measurements' influences of porous structures in LHP on heat removal from the insulated gate bipolar transistor (IGBT) have been made. PMID:24959622

Formation of tRNA granules in the nucleus of heat-induced human cells

International Nuclear Information System (INIS)

Miyagawa, Ryu; Mizuno, Rie; Watanabe, Kazunori; Ijiri, Kenichi

2012-01-01

Highlights: ► tRNAs are tranlocated into the nucleus in heat-induced HeLa cells. ► tRNAs form the unique granules in the nucleus. ► tRNA ganules overlap with nuclear stress granules. -- Abstract: The stress response, which can trigger various physiological phenomena, is important for living organisms. For instance, a number of stress-induced granules such as P-body and stress granule have been identified. These granules are formed in the cytoplasm under stress conditions and are associated with translational inhibition and mRNA decay. In the nucleus, there is a focus named nuclear stress body (nSB) that distinguishes these structures from cytoplasmic stress granules. Many splicing factors and long non-coding RNA species localize in nSBs as a result of stress. Indeed, tRNAs respond to several kinds of stress such as heat, oxidation or starvation. Although nuclear accumulation of tRNAs occurs in starved Saccharomyces cerevisiae, this phenomenon is not found in mammalian cells. We observed that initiator tRNA Met (Meti) is actively translocated into the nucleus of human cells under heat stress. During this study, we identified unique granules of Meti that overlapped with nSBs. Similarly, elongator tRNA Met was translocated into the nucleus and formed granules during heat stress. Formation of tRNA granules is closely related to the translocation ratio. Then, all tRNAs may form the specific granules.

Formation of tRNA granules in the nucleus of heat-induced human cells

Energy Technology Data Exchange (ETDEWEB)

Miyagawa, Ryu [Radioisotope Center, The University of Tokyo, 2-11-16 Yayoi, Bunkyo-ku, Tokyo 113-0032 (Japan); Department of Biological Science, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8654 (Japan); Mizuno, Rie [Radioisotope Center, The University of Tokyo, 2-11-16 Yayoi, Bunkyo-ku, Tokyo 113-0032 (Japan); Watanabe, Kazunori, E-mail: watanabe@ric.u-tokyo.ac.jp [Radioisotope Center, The University of Tokyo, 2-11-16 Yayoi, Bunkyo-ku, Tokyo 113-0032 (Japan); Ijiri, Kenichi [Radioisotope Center, The University of Tokyo, 2-11-16 Yayoi, Bunkyo-ku, Tokyo 113-0032 (Japan); Department of Biological Science, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8654 (Japan)

2012-02-03

Highlights: Black-Right-Pointing-Pointer tRNAs are tranlocated into the nucleus in heat-induced HeLa cells. Black-Right-Pointing-Pointer tRNAs form the unique granules in the nucleus. Black-Right-Pointing-Pointer tRNA ganules overlap with nuclear stress granules. -- Abstract: The stress response, which can trigger various physiological phenomena, is important for living organisms. For instance, a number of stress-induced granules such as P-body and stress granule have been identified. These granules are formed in the cytoplasm under stress conditions and are associated with translational inhibition and mRNA decay. In the nucleus, there is a focus named nuclear stress body (nSB) that distinguishes these structures from cytoplasmic stress granules. Many splicing factors and long non-coding RNA species localize in nSBs as a result of stress. Indeed, tRNAs respond to several kinds of stress such as heat, oxidation or starvation. Although nuclear accumulation of tRNAs occurs in starved Saccharomyces cerevisiae, this phenomenon is not found in mammalian cells. We observed that initiator tRNA{sup Met} (Meti) is actively translocated into the nucleus of human cells under heat stress. During this study, we identified unique granules of Meti that overlapped with nSBs. Similarly, elongator tRNA{sup Met} was translocated into the nucleus and formed granules during heat stress. Formation of tRNA granules is closely related to the translocation ratio. Then, all tRNAs may form the specific granules.

Heat transfer and pressure drop characteristics of mini-fin structures

International Nuclear Information System (INIS)

Jiang Peixue; Xu Ruina

2007-01-01

Forced convection heat transfer of air and water in bronze and pure copper mini-fin structures and mini-channel structures was investigated experimentally. The mini-fin dimensions were 0.7 mm x 0.2 mm and 0.8 mm x 0.4 mm. The tests included both staggered diamond-shaped and in-line square mini-fin arrangements. The tests investigated the effects of structures, mini-fin dimensions and arrangement, test section materials, and fluid properties on the convection heat transfer and heat transfer enhancement. For the tested conditions, the convection heat transfer coefficient was increased 9-21 fold for water and 12-38 fold for air in the mini-fin structures compared with an empty plate channel. The friction factor and flow resistance in the mini-channel structures and the in-line square mini-fin arrangement were much less than in the staggered diamond-shaped mini-fin arrangement. For the small channel width, W c = 0.2 mm, the convection heat transfer with the in-line square array structure was more intense than with the staggered diamond-shaped structure, the mini-channel structure or the porous media. For the larger channel width, W c = 0.4 mm, the convection heat transfer in the staggered diamond-shaped array structure was more intense than in the others systems while the in-line square structure had the best overall thermal-hydraulic performance

Boiling phenomenon and heat transfer in bead-packed porous structure

International Nuclear Information System (INIS)

Zhang Xiaojie; ZHu Yanlei; Bai Bofeng; Yan Xiao; Xiao Zejun

2009-01-01

A visual study on pool boiling behavior and phase distribution was conducted on the porous structures made of staggered glass beads at atmospheric pressure. The bead-packed structure was heated on the bottom. The investigations were carried out respectively at different glass bead diameters which were 4 mm, 6 mm and 8 mm. The results show that during subcooled boiling, small isolated bubbles are formed on the heated surface and combine into main-bubbles, the dispersion frequency of the main-bubbles is low and the small bubbles scatter in the bead-packed porous structures. At the initial stage of saturated boiling, the bubble growth rate, the volume of main-bubbles and the range of continuous vapor phase increase. The dispersion frequency of main-bubbles increases with the increasing of heat flux. During film boiling, the heated surface is absolutely covered with vapor film and the porous structure is full of liquid. The larger the diameter of beads is, the higher heat flux is needed for the same phenomenon, and the higher maximum value of heat transfer coefficient will be. During the whole saturated boiling, and the heat transfer enhanced firstly and then weakened. Being opposite to that of the diameters of 4 mm and 8 mm, the heat transfer coefficient in the 6 mm-bead-packed porous structure decreases with the increasing of the heat flux. (authors)

Structure design of primary heat-exchanger for the MHWRR

International Nuclear Information System (INIS)

Li Yanshui; Cao Zhibin

1999-01-01

Primary heat-exchanger is one of the key equipment in the Multi-application Heavy Water Research Reactor (MHWRR). Its structure design ought to meet as much possible as the demands for safety, feasibility and economy. To reduce the liquid resistance, the locating structure between inner tube and outer tube is distributed spirally. The edge of outer tube is processed in the shape of hexahedron and then splice-welded into honeycomb structure thereby the heat-exchanger has the smallest outer diameter compared with that with the same heat-exchanging area according to 'Normal Design', 'Anabasis Design' is applied to the design for parts with Safety Class I, to ensure safety of the heat-exchanger

Heat transfer and flow structure evaluation of a synthetic jet emanating from a planar heat sink

International Nuclear Information System (INIS)

Manning, Paul; Persoons, Tim; Murray, Darina

2014-01-01

Direct impinging synthetic jets are a proven method for heat transfer enhancement, and have been subject to extensive research. However, despite the vast amount of research into direct synthetic jet impingement, there has been little research investigating the effects of a synthetic jet emanating from a heated surface, this forms the basis of the current research investigation. Both single and multiple orifices are integrated into a planar heat sink forming a synthetic jet, thus allowing the heat transfer enhancement and flow structures to be assessed. The heat transfer analysis highlighted that the multiple orifice synthetic jet resulted in the greatest heat transfer enhancements. The flow structures responsible for these enhancements were identified using a combination of flow visualisation, thermal imaging and thermal boundary layer analysis. The flow structure analysis identified that the synthetic jets decreased the thermal boundary layer thickness resulting in a more effective convective heat transfer process. Flow visualisation revealed entrainment of local air adjacent to the heated surface; this occurred from vortex roll-up at the surface of the heat sink and from the highly sheared jet flow. Furthermore, a secondary entrainment was identified which created a surface impingement effect. It is proposed that all three flow features enhance the heat transfer characteristics of the system.

Photo-induced-heat localization on nanostructured metallic glasses

Science.gov (United States)

Uzun, Ceren; Kahler, Niloofar; Grave de Peralta, Luis; Kumar, Golden; Bernussi, Ayrton A.

2017-09-01

Materials with large photo-thermal energy conversion efficiency are essential for renewable energy applications. Photo-excitation is an effective approach to generate controlled and localized heat at relatively low excitation optical powers. However, lateral heat diffusion to the surrounding illuminated areas accompanied by low photo-thermal energy conversion efficiency remains a challenge for metallic surfaces. Surface nanoengineering has proven to be a successful approach to further absorption and heat generation. Here, we show that pronounced spatial heat localization and high temperatures can be achieved with arrays of amorphous metallic glass nanorods under infrared optical illumination. Thermography measurements revealed marked temperature contrast between illuminated and non-illuminated areas even under low optical power excitation conditions. This attribute allowed for generating legible photo-induced thermal patterns on textured metallic glass surfaces.

Heat Removal from Bipolar Transistor by Loop Heat Pipe with Nickel and Copper Porous Structures

Directory of Open Access Journals (Sweden)

Patrik Nemec

2014-01-01

Full Text Available Loop heat pipes (LHPs are used in many branches of industry, mainly for cooling of electrical elements and systems. The loop heat pipe is a vapour-liquid phase-change device that transfers heat from evaporator to condenser. One of the most important parts of the LHP is the porous wick structure. The wick structure provides capillary force to circulate the working fluid. To achieve good thermal performance of LHP, capillary wicks with high permeability and porosity and fine pore radius are expected. The aim of this work was to develop porous structures from copper and nickel powder with different grain sizes. For experiment copper powder with grain size of 50 and 100 μm and nickel powder with grain size of 10 and 25 μm were used. Analysis of these porous structures and LHP design are described in the paper. And the measurements’ influences of porous structures in LHP on heat removal from the insulated gate bipolar transistor (IGBT have been made.

A Study on Conjugate Heat Transfer Analysis of Reactor Vessel including Irradiated Structural Heat Source

Energy Technology Data Exchange (ETDEWEB)

Yi, Kunwoo; Cho, Hyuksu; Im, Inyoung; Kim, Eunkee [KEPCO EnC, Daejeon (Korea, Republic of)

2015-10-15

Though Material reliability programs (MRPs) have a purpose to provide the evaluation or management methodologies for the operating RVI, the similar evaluation methodologies can be applied to the APR1400 fleet in the design stage for the evaluation of neutron irradiation effects. The purposes of this study are: to predict the thermal behavior whether or not irradiated structure heat source; to evaluate effective thermal conductivity (ETC) in relation to isotropic and anisotropic conductivity of porous media for APR1400 Reactor Vessel. The CFD simulations are performed so as to evaluate thermal behavior whether or not irradiated structure heat source and effective thermal conductivity for APR1400 Reactor Vessel. In respective of using irradiated structure heat source, the maximum temperature of fluid and core shroud for isotropic ETC are 325.8 .deg. C, 341.5 .deg. C. The total amount of irradiated structure heat source is about 5.41 MWth and not effect to fluid temperature.

Practical Considerations for Thermal Stresses Induced by Surface Heating

International Nuclear Information System (INIS)

Blanchard, James P.

2003-01-01

Rapid surface heating can induce large stresses in solids. A relatively simple model, assuming full constraint in two dimensions and no constraint in the third dimension, can adequately model stresses in a wide variety of situations. This paper derives this simple model, and supports it with criteria for its validity. Phenomena that are considered include non-zero penetration depths for the heat deposition, spatial non-uniformity in the surface heating, and elastic waves. Models for each of these cases, using simplified geometries, are used to develop quantitative limits for their applicability

Large deviations in stochastic heat-conduction processes provide a gradient-flow structure for heat conduction

International Nuclear Information System (INIS)

Peletier, Mark A.; Redig, Frank; Vafayi, Kiamars

2014-01-01

We consider three one-dimensional continuous-time Markov processes on a lattice, each of which models the conduction of heat: the family of Brownian Energy Processes with parameter m (BEP(m)), a Generalized Brownian Energy Process, and the Kipnis-Marchioro-Presutti (KMP) process. The hydrodynamic limit of each of these three processes is a parabolic equation, the linear heat equation in the case of the BEP(m) and the KMP, and a nonlinear heat equation for the Generalized Brownian Energy Process with parameter a (GBEP(a)). We prove the hydrodynamic limit rigorously for the BEP(m), and give a formal derivation for the GBEP(a). We then formally derive the pathwise large-deviation rate functional for the empirical measure of the three processes. These rate functionals imply gradient-flow structures for the limiting linear and nonlinear heat equations. We contrast these gradient-flow structures with those for processes describing the diffusion of mass, most importantly the class of Wasserstein gradient-flow systems. The linear and nonlinear heat-equation gradient-flow structures are each driven by entropy terms of the form −log ρ; they involve dissipation or mobility terms of order ρ 2 for the linear heat equation, and a nonlinear function of ρ for the nonlinear heat equation

A susceptor heating structure in MOVPE reactor by induction heating

International Nuclear Information System (INIS)

Li, Zhiming; Li, Hailing; Zhang, Jincheng; Li, Jinping; Jiang, Haiying; Fu, Xiaoqian; Han, Yanbin; Xia, Yingjie; Huang, Yimei; Yin, Jianqin; Zhang, Lejuan; Hu, Shigang

2014-01-01

A novel susceptor with a revolutionary V-shaped slot of solid of revolution form is proposed in the metalorganic vapor phase epitaxy (MOVPE) reactor by induction heating. This slot changes the heat transfer rate as the generated heat is transferred from the high temperature region of the susceptor to the substrate, which improves the uniformity of the substrate temperature distribution. By using finite element method (FEM), the susceptor with this structure for heating the substrate of six inches in diameter is optimized. It is observed that this optimized susceptor with the V-shaped slot makes the uniformity of the substrate temperature distribution improve more than 80%, which can be beneficial to the film growth. - Highlights: •A novel susceptor with V-shaped slot in MOVPE reactor is proposed. •Temperature in the substrate is optimized. •Great temperature uniformity of the substrate is obtained

Analysis of fluid flow and heat transfer in a double pipe heat exchanger with porous structures

International Nuclear Information System (INIS)

Targui, N.; Kahalerras, H.

2008-01-01

A numerical study of flow and heat transfer characteristics is made in a double pipe heat exchanger with porous structures inserted in the annular gap in two configurations: on the inner cylinder (A) and on both the cylinders in a staggered fashion (B). The flow field in the porous regions is modelled by the Darcy-Brinkman-Forchheimer model and the finite volume method is used to solve the governing equations. The effects of several parameters such as Darcy number, porous structures thickness and spacing and thermal conductivity ratio are considered in order to look for the most appropriate properties of the porous structures that allow optimal heat transfer enhancement. It is found that the highest heat transfer rates are obtained when the porous structures are attached in configuration B especially at small spacing and high thicknesses

Flow-excursion-induced dryout at low-heat-flux

International Nuclear Information System (INIS)

Khatib-Rahbar, M.; Cazzoli, E.G.

1983-01-01

Flow-excursion-induced dryout at low-heat-flux natural-convection boiling, typical of liquid-metal fast-breeder reactors, is addressed. Steady-state calculations indicate that low-quality boiling is possible up to the point of Ledinegg instability leading to flow excursion and subsequent dryout in agreement with experimental data. A flow-regime-dependent dryout heat flux relationship based upon saturated boiling criterion is also presented. Transient analysis indicates that premature flow excursion can not be ruled out and sodium boiling is highly transient dependent. Analysis of a high-heat-flux forced convection, loss-of-flow transient shows a significantly faster flow excursion leading to dryout in excellent agreement with parallel calculations using the two-dimensional THORAX code. 17 figures

Micro-structured heat exchanger for cryogenic mixed refrigerant cycles

Science.gov (United States)

Gomse, D.; Reiner, A.; Rabsch, G.; Gietzelt, T.; Brandner, J. J.; Grohmann, S.

2017-12-01

Mixed refrigerant cycles (MRCs) offer a cost- and energy-efficient cooling method for the temperature range between 80 and 200 K. The performance of MRCs is strongly influenced by entropy production in the main heat exchanger. High efficiencies thus require small temperature gradients among the fluid streams, as well as limited pressure drop and axial conduction. As temperature gradients scale with heat flux, large heat transfer areas are necessary. This is best achieved with micro-structured heat exchangers, where high volumetric heat transfer areas can be realized. The reliable design of MRC heat exchangers is challenging, since two-phase heat transfer and pressure drop in both fluid streams have to be considered simultaneously. Furthermore, only few data on the convective boiling and condensation kinetics of zeotropic mixtures is available in literature. This paper presents a micro-structured heat exchanger designed with a newly developed numerical model, followed by experimental results on the single-phase pressure drop and their implications on the hydraulic diameter.

Heat-induced changes to lipid molecular structure in Vimy flaxseed: Spectral intensity and molecular clustering

Science.gov (United States)

Yu, Peiqiang; Damiran, Daalkhaijav

2011-06-01

Autoclaving was used to manipulate nutrient utilization and availability. The objectives of this study were to characterize any changes of the functional groups mainly associated with lipid structure in flaxseed ( Linum usitatissimum, cv. Vimy), that occurred on a molecular level during the treatment process using infrared Fourier transform molecular spectroscopy. The parameters included lipid CH 3 asymmetric (ca. 2959 cm -1), CH 2 asymmetric (ca. 2928 cm -1), CH 3 symmetric (ca. 2871 cm -1) and CH 2 symmetric (ca. 2954 cm -1) functional groups, lipid carbonyl C dbnd O ester group (ca. 1745 cm -1), lipid unsaturation group (CH attached to C dbnd C) (ca. 3010 cm -1) as well as their ratios. Hierarchical cluster analysis (CLA) and principal components analysis (PCA) were conducted to identify molecular spectral differences. Flaxseed samples were kept raw for the control or autoclaved in batches at 120 °C for 20, 40 or 60 min for treatments 1, 2 and 3, respectively. Molecular spectral analysis of lipid functional group ratios showed a significant decrease ( P 0.05) on lipid carbonyl C dbnd O ester group and lipid unsaturation group (CH attached to C dbnd C) (with average spectral peak area intensities of 138.3 and 68.8 IR intensity units, respectively). Multivariate molecular spectral analyses, CLA and PCA, were unable to make distinctions between the different treatment original spectra at the CH 3 and CH 2 asymmetric and symmetric region (ca. 2988-2790 cm -1). The results indicated that autoclaving had an impact to the mid-infrared molecular spectrum of flaxseed to identify heat-induced changes in lipid conformation. A future study is needed to quantify the relationship between lipid molecular structure changes and functionality/availability.

Maximum skin hyperaemia induced by local heating: possible mechanisms.

Science.gov (United States)

Gooding, Kim M; Hannemann, Michael M; Tooke, John E; Clough, Geraldine F; Shore, Angela C

2006-01-01

Maximum skin hyperaemia (MH) induced by heating skin to > or = 42 degrees C is impaired in individuals at risk of diabetes and cardiovascular disease. Interpretation of these findings is hampered by the lack of clarity of the mechanisms involved in the attainment of MH. MH was achieved by local heating of skin to 42-43 degrees C for 30 min, and assessed by laser Doppler fluximetry. Using double-blind, randomized, placebo-controlled crossover study designs, the roles of prostaglandins were investigated by inhibiting their production with aspirin and histamine, with the H1 receptor antagonist cetirizine. The nitric oxide (NO) pathway was blocked by the NO synthase inhibitor, NG-nitro-L-arginine methyl esther (L-NAME), and enhanced by sildenafil (prevents breakdown of cGMP). MH was not altered by aspirin, cetirizine or sildenafil, but was reduced by L-NAME: median placebo 4.48 V (25th, 75th centiles: 3.71, 4.70) versus L-NAME 3.25 V (3.10, 3.80) (p = 0.008, Wilcoxon signed rank test). Inhibition of NO production (L-NAME) resulted in a more rapid reduction in hyperaemia after heating (p = 0.011), whereas hyperaemia was prolonged in the presence of sildenafil (p = 0.003). The increase in skin blood flow was largely confined to the directly heated area, suggesting that the role of heat-induced activation of the axon reflex was small. NO, but not prostaglandins, histamine or an axon reflex, contributes to the increase in blood flow on heating and NO is also a component of the resolution of MH after heating. Copyright 2006 S. Karger AG, Basel.

Noxious heat and scratching decrease histamine-induced itch and skin blood flow.

Science.gov (United States)

Yosipovitch, Gil; Fast, Katharine; Bernhard, Jeffrey D

2005-12-01

The aim of this study was to assess the effect of thermal stimuli or distal scratching on skin blood flow and histamine-induced itch in healthy volunteers. Twenty-one healthy volunteers participated in the study. Baseline measurements of skin blood flow were obtained on the flexor aspect of the forearm. These measurements were compared with skin blood flow after various stimuli: heating the skin, cooling the skin, noxious cold 2 degrees C, noxious heat 49 degrees C, and scratching via a brush with controlled pressure. Afterwards histamine iontophoresis was performed and skin blood flow and itch intensity were measured immediately after the above-mentioned stimuli. Scratching reduced mean histamine-induced skin blood flow and itch intensity. Noxious heat pain increased basal skin blood flow but reduced histamine-induced maximal skin blood flow and itch intensity. Cold pain and cooling reduced itch intensity, but neither affected histamine-induced skin blood flow. Sub-noxious warming the skin did not affect the skin blood flow or itch intensity. These findings suggest that heat pain and scratching may inhibit itch through a neurogenic mechanism that also affects skin blood flow.

Detailing Radio Frequency Heating Induced by Coronary Stents: A 7.0 Tesla Magnetic Resonance Study

Science.gov (United States)

Santoro, Davide; Winter, Lukas; Müller, Alexander; Vogt, Julia; Renz, Wolfgang; Özerdem, Celal; Grässl, Andreas; Tkachenko, Valeriy; Schulz-Menger, Jeanette; Niendorf, Thoralf

2012-01-01

The sensitivity gain of ultrahigh field Magnetic Resonance (UHF-MR) holds the promise to enhance spatial and temporal resolution. Such improvements could be beneficial for cardiovascular MR. However, intracoronary stents used for treatment of coronary artery disease are currently considered to be contra-indications for UHF-MR. The antenna effect induced by a stent together with RF wavelength shortening could increase local radiofrequency (RF) power deposition at 7.0 T and bears the potential to induce local heating, which might cause tissue damage. Realizing these constraints, this work examines RF heating effects of stents using electro-magnetic field (EMF) simulations and phantoms with properties that mimic myocardium. For this purpose, RF power deposition that exceeds the clinical limits was induced by a dedicated birdcage coil. Fiber optic probes and MR thermometry were applied for temperature monitoring using agarose phantoms containing copper tubes or coronary stents. The results demonstrate an agreement between RF heating induced temperature changes derived from EMF simulations versus MR thermometry. The birdcage coil tailored for RF heating was capable of irradiating power exceeding the specific-absorption rate (SAR) limits defined by the IEC guidelines by a factor of three. This setup afforded RF induced temperature changes up to +27 K in a reference phantom. The maximum extra temperature increase, induced by a copper tube or a coronary stent was less than 3 K. The coronary stents examined showed an RF heating behavior similar to a copper tube. Our results suggest that, if IEC guidelines for local/global SAR are followed, the extra RF heating induced in myocardial tissue by stents may not be significant versus the baseline heating induced by the energy deposited by a tailored cardiac transmit RF coil at 7.0 T, and may be smaller if not insignificant than the extra RF heating observed under the circumstances used in this study. PMID:23185498

Detailing radio frequency heating induced by coronary stents: a 7.0 Tesla magnetic resonance study.

Directory of Open Access Journals (Sweden)

Davide Santoro

Full Text Available The sensitivity gain of ultrahigh field Magnetic Resonance (UHF-MR holds the promise to enhance spatial and temporal resolution. Such improvements could be beneficial for cardiovascular MR. However, intracoronary stents used for treatment of coronary artery disease are currently considered to be contra-indications for UHF-MR. The antenna effect induced by a stent together with RF wavelength shortening could increase local radiofrequency (RF power deposition at 7.0 T and bears the potential to induce local heating, which might cause tissue damage. Realizing these constraints, this work examines RF heating effects of stents using electro-magnetic field (EMF simulations and phantoms with properties that mimic myocardium. For this purpose, RF power deposition that exceeds the clinical limits was induced by a dedicated birdcage coil. Fiber optic probes and MR thermometry were applied for temperature monitoring using agarose phantoms containing copper tubes or coronary stents. The results demonstrate an agreement between RF heating induced temperature changes derived from EMF simulations versus MR thermometry. The birdcage coil tailored for RF heating was capable of irradiating power exceeding the specific-absorption rate (SAR limits defined by the IEC guidelines by a factor of three. This setup afforded RF induced temperature changes up to +27 K in a reference phantom. The maximum extra temperature increase, induced by a copper tube or a coronary stent was less than 3 K. The coronary stents examined showed an RF heating behavior similar to a copper tube. Our results suggest that, if IEC guidelines for local/global SAR are followed, the extra RF heating induced in myocardial tissue by stents may not be significant versus the baseline heating induced by the energy deposited by a tailored cardiac transmit RF coil at 7.0 T, and may be smaller if not insignificant than the extra RF heating observed under the circumstances used in this study.

Heat Transfer Characteristics of SiC-coated Heat Pipe for Passive Decay Heat Removal

International Nuclear Information System (INIS)

Kim, Kyung Mo; Kim, In Guk; Jeong, Yeong Shin; Bang, In Cheol

2014-01-01

The main concern with the Fukushima accident was the failure of active and passive core cooling systems. The main function of existing passive decay heat removal systems is feeding additional coolant to the reactor core. Thus, an established emergency core cooling system (ECCS) cannot operate properly because of impossible depressurization under the station blackout (SBO) condition. Therefore, a new concept for passive decay heat removal system is required. In this study, an innovative hybrid control rod concept is considered for passive in-core decay heat removal that differs from the existing direct vessel injection core cooling system and passive auxiliary feedwater system (PAFS). The heat transfer between the evaporator and condenser sections occurs by phase change of the working fluid and capillary action induced by wick structures installed on the inner wall of the heat pipe. In this study, a hybrid control rod is developed to take the roles of both neutron absorption and heat removal by combining the functions of a heat pipe and control rod. Previous studies on enhancing the heat removal capacity of heat pipes used nanofluids, self-rewetting fluids, various wick structures and condensers. Many studies have examined the thermal performances of heat pipes using various nanofluids. They concluded that the enhanced thermal performance of the heat pipe using nanofluids is due to nanoparticle deposition on the wick structures. Thus, the wick structure of heat pipes has been modified by nanoparticle deposition to enhance the heat removal capacity. However, previous studies used relatively small heat pipes and narrow ranges of heat loads. The environment of a nuclear reactor is very specific, and the decay heat produced by fission products after shutdown is relatively large. Thus, this study tested a large-scale heat pipe over a wide range of power. The concept of a hybrid heat pipe for an advanced in-core decay heat removal system was introduced for complete

Heat Transfer Characteristics of SiC-coated Heat Pipe for Passive Decay Heat Removal

Energy Technology Data Exchange (ETDEWEB)

Kim, Kyung Mo; Kim, In Guk; Jeong, Yeong Shin; Bang, In Cheol [Ulsan National Institute of Science and Technology, Ulsan (Korea, Republic of)

2014-10-15

The main concern with the Fukushima accident was the failure of active and passive core cooling systems. The main function of existing passive decay heat removal systems is feeding additional coolant to the reactor core. Thus, an established emergency core cooling system (ECCS) cannot operate properly because of impossible depressurization under the station blackout (SBO) condition. Therefore, a new concept for passive decay heat removal system is required. In this study, an innovative hybrid control rod concept is considered for passive in-core decay heat removal that differs from the existing direct vessel injection core cooling system and passive auxiliary feedwater system (PAFS). The heat transfer between the evaporator and condenser sections occurs by phase change of the working fluid and capillary action induced by wick structures installed on the inner wall of the heat pipe. In this study, a hybrid control rod is developed to take the roles of both neutron absorption and heat removal by combining the functions of a heat pipe and control rod. Previous studies on enhancing the heat removal capacity of heat pipes used nanofluids, self-rewetting fluids, various wick structures and condensers. Many studies have examined the thermal performances of heat pipes using various nanofluids. They concluded that the enhanced thermal performance of the heat pipe using nanofluids is due to nanoparticle deposition on the wick structures. Thus, the wick structure of heat pipes has been modified by nanoparticle deposition to enhance the heat removal capacity. However, previous studies used relatively small heat pipes and narrow ranges of heat loads. The environment of a nuclear reactor is very specific, and the decay heat produced by fission products after shutdown is relatively large. Thus, this study tested a large-scale heat pipe over a wide range of power. The concept of a hybrid heat pipe for an advanced in-core decay heat removal system was introduced for complete

Effects of propofol on damage of rat intestinal epithelial cells induced by heat stress and lipopolysaccharides

Energy Technology Data Exchange (ETDEWEB)

Tang, J.; Jiang, Y. [Southern Medical University, Nanfang Hospital, Department of Anesthesia, Guangzhou, China, Department of Anesthesia, Nanfang Hospital, Southern Medical University, Guangzhou (China); Tang, Y.; Chen, B. [Guangzhou General Hospital of Guangzhou Military Command, Department of Intensive Care Unit, Guangzhou, China, Department of Intensive Care Unit, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou (China); Sun, X. [Laboratory of Traditional Chinese Medicine Syndrome, School of Traditional Chinese Medicine, Southern Medical University, Guangzhou (China); Su, L.; Liu, Z. [Guangzhou General Hospital of Guangzhou Military Command, Department of Intensive Care Unit, Guangzhou, China, Department of Intensive Care Unit, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou (China)

2013-06-25

Gut-derived endotoxin and pathogenic bacteria have been proposed as important causative factors of morbidity and death during heat stroke. However, it is still unclear what kind of damage is induced by heat stress. In this study, the rat intestinal epithelial cell line (IEC-6) was treated with heat stress or a combination of heat stress and lipopolysaccharide (LPS). In addition, propofol, which plays an important role in anti-inflammation and organ protection, was applied to study its effects on cellular viability and apoptosis. Heat stress, LPS, or heat stress combined with LPS stimulation can all cause intestinal epithelial cell damage, including early apoptosis and subsequent necrosis. However, propofol can alleviate injuries caused by heat stress, LPS, or the combination of heat stress and LPS. Interestingly, propofol can only mitigate LPS-induced intestinal epithelial cell apoptosis, and has no protective role in heat-stress-induced apoptosis. This study developed a model that can mimic the intestinal heat stress environment. It demonstrates the effects on intestinal epithelial cell damage, and indicated that propofol could be used as a therapeutic drug for the treatment of heat-stress-induced intestinal injuries.

Effects of propofol on damage of rat intestinal epithelial cells induced by heat stress and lipopolysaccharides

International Nuclear Information System (INIS)

Tang, J.; Jiang, Y.; Tang, Y.; Chen, B.; Sun, X.; Su, L.; Liu, Z.

2013-01-01

Gut-derived endotoxin and pathogenic bacteria have been proposed as important causative factors of morbidity and death during heat stroke. However, it is still unclear what kind of damage is induced by heat stress. In this study, the rat intestinal epithelial cell line (IEC-6) was treated with heat stress or a combination of heat stress and lipopolysaccharide (LPS). In addition, propofol, which plays an important role in anti-inflammation and organ protection, was applied to study its effects on cellular viability and apoptosis. Heat stress, LPS, or heat stress combined with LPS stimulation can all cause intestinal epithelial cell damage, including early apoptosis and subsequent necrosis. However, propofol can alleviate injuries caused by heat stress, LPS, or the combination of heat stress and LPS. Interestingly, propofol can only mitigate LPS-induced intestinal epithelial cell apoptosis, and has no protective role in heat-stress-induced apoptosis. This study developed a model that can mimic the intestinal heat stress environment. It demonstrates the effects on intestinal epithelial cell damage, and indicated that propofol could be used as a therapeutic drug for the treatment of heat-stress-induced intestinal injuries

Numerical study on flow induced vibration characteristics of heat transfer tube

International Nuclear Information System (INIS)

Feng Zhipeng; Zang Fenggang; Zhang Yixiong

2014-01-01

The model presents a fully coupled approach with solving the fluid flow and the structure vibration simultaneously. The three-dimensional unsteady, viscous, incompressible Navier-Stokes equation and LES turbulence model were solved by the finite volume approach and the heat transfer structure was solved by finite element method combined with moving mesh control technique. The dynamic equilibrium equation was discretized according to the finite element theory and the mesh update was achieved by the dynamic mesh technology. Based on this model, flow induced vibration responses of the tube were thus investigated using response branch, phase angle, Lissajou diagram, trajectory, phase portrait and Poincare section mapping. Meanwhile, the limit cycle and bifurcation of lift coefficient and lateral displacement were analyzed. The results reveal that a quasi-upper branch is found in the fluid-structure interaction system, and there is no bifurcation of lift coefficient and lateral displacement occurred in three-dimensional flexible tube submitted to uniform turbulent flow. (authors)

A Method of Heat Exchange Structure Optimization of the Cricoid Plastic Parts

Directory of Open Access Journals (Sweden)

Dongpo Yang

2014-01-01

Full Text Available This paper research on the effect of heat transfer performance of ring wall structure change of ship water heater top cricoid hood. A method of equivalent conversion is applied on simplify the structure of finned tube heat exchanger, it distinct reduce the computational grid, and improve the simulation speed and accuracy. This method can be used to calculate the ventilation and heat transfer of that compact configuration type structure in the complex component. Changing the ring wall structure can improve heat transfer performance, based on the method of equivalent transformation, a new heat transfer structure is established.

Flow-induced vibration analysis of heat exchanger and steam generator designs

International Nuclear Information System (INIS)

Pettigrew, M.J.; Sylvestre, Y.; Campagna, A.O.

1977-08-01

Tube and shell heat exchange components such as steam generators, heat exchangers and condensers are essential parts of CANDU nuclear power stations. Excessive flow-induced vibration may cause tube failures by fatigue or more likely by fretting-wear. Such failures may lead to station shutdowns that are very undesirable in terms of lost production. Hence good performance and reliability dictate a thorough flow-induced vibration analysis at the design stage. This paper presents our approach and techniques in this respect. (author)

Influence of Joule heating on current-induced domain wall depinning

Energy Technology Data Exchange (ETDEWEB)

Moretti, Simone, E-mail: simone.moretti@usal.es; Raposo, Victor; Martinez, Eduardo [University of Salamanca, Plaza de los Caidos, 37008 Salamanca (Spain)

2016-06-07

The domain wall depinning from a notch in a Permalloy nanostrip on top of a SiO{sub 2}/Si substrate is studied theoretically under application of static magnetic fields and the injection of short current pulses. The influence of Joule heating on current-induced domain wall depinning is explored self-consistently by coupling the magnetization dynamics in the ferromagnetic strip to the heat transport throughout the system. Our results indicate that Joule heating plays a remarkable role in these processes, resulting in a reduction in the critical depinning field and/or in a temporary destruction of the ferromagnetic order for typically injected current pulses. In agreement with experimental observations, similar pinning-depinning phase diagrams can be deduced for both current polarities when the Joule heating is taken into account. These observations, which are incompatible with the sole contribution of spin transfer torques, provide a deeper understanding of the physics underlying these processes and establish the real scope of the spin transfer torque. They are also relevant for technological applications based on current-induced domain-wall motion along soft strips.

Spin heat accumulation induced by tunneling from a ferromagnet.

Science.gov (United States)

Vera-Marun, I J; van Wees, B J; Jansen, R

2014-02-07

An electric current from a ferromagnet into a nonmagnetic material can induce a spin-dependent electron temperature. Here, it is shown that this spin heat accumulation, when created by tunneling from a ferromagnet, produces a non-negligible voltage signal that is comparable to that due to the coexisting electrical spin accumulation and can give a different Hanle spin precession signature. The effect is governed by the spin polarization of the Peltier coefficient of the tunnel contact, its Seebeck coefficient, and the spin heat resistance of the nonmagnetic material, which is related to the electrical spin resistance by a spin-Wiedemann-Franz law. Moreover, spin heat injection is subject to a heat conductivity mismatch that is overcome if the tunnel interface has a sufficiently large resistance.

Intergenic sequence between Arabidopsis caseinolytic protease B-cytoplasmic/heat shock protein100 and choline kinase genes functions as a heat-inducible bidirectional promoter.

Science.gov (United States)

Mishra, Ratnesh Chandra; Grover, Anil

2014-11-01

In Arabidopsis (Arabidopsis thaliana), the At1g74310 locus encodes for caseinolytic protease B-cytoplasmic (ClpB-C)/heat shock protein100 protein (AtClpB-C), which is critical for the acquisition of thermotolerance, and At1g74320 encodes for choline kinase (AtCK2) that catalyzes the first reaction in the Kennedy pathway for phosphatidylcholine biosynthesis. Previous work has established that the knockout mutants of these genes display heat-sensitive phenotypes. While analyzing the AtClpB-C promoter and upstream genomic regions in this study, we noted that AtClpB-C and AtCK2 genes are head-to-head oriented on chromosome 1 of the Arabidopsis genome. Expression analysis showed that transcripts of these genes are rapidly induced in response to heat stress treatment. In stably transformed Arabidopsis plants harboring this intergenic sequence between head-to-head oriented green fluorescent protein and β-glucuronidase reporter genes, both transcripts and proteins of the two reporters were up-regulated upon heat stress. Four heat shock elements were noted in the intergenic region by in silico analysis. In the homozygous transfer DNA insertion mutant Salk_014505, 4,393-bp transfer DNA is inserted at position -517 upstream of ATG of the AtClpB-C gene. As a result, AtCk2 loses proximity to three of the four heat shock elements in the mutant line. Heat-inducible expression of the AtCK2 transcript was completely lost, whereas the expression of AtClpB-C was not affected in the mutant plants. Our results suggest that the 1,329-bp intergenic fragment functions as a heat-inducible bidirectional promoter and the region governing the heat inducibility is possibly shared between the two genes. We propose a model in which AtClpB-C shares its regulatory region with heat-induced choline kinase, which has a possible role in heat signaling. © 2014 American Society of Plant Biologists. All Rights Reserved.

Heat transfer and thermal stress analysis in fluid-structure coupled field

International Nuclear Information System (INIS)

Li, Ming-Jian; Pan, Jun-Hua; Ni, Ming-Jiu; Zhang, Nian-Mei

2015-01-01

In this work, three-dimensional simulation on conjugate heat transfer in a fluid-structure coupled field was carried out. The structure considered is from the dual-coolant lithium-lead (DCLL) blanket, which is the key technology of International Thermo-nuclear Experimental Reactor (ITER). The model was developed based on finite element-finite volume method and was employed to investigate mechanical behaviours of Flow Channel Insert (FCI) and heat transfer in the blanket under nuclear reaction. Temperature distribution, thermal deformation and thermal stresses were calculated in this work, and the effects of thermal conductivity, convection heat transfer coefficient and flow velocity were analyzed. Results show that temperature gradients and thermal stresses of FCI decrease when FCI has better heat conductivity. Higher convection heat transfer coefficient will result in lower temperature, thermal deformations and stresses in FCI. Analysis in this work could be a theoretical basis of blanket optimization. - Highlights: • We use FVM and FEM to investigate FCI structural safety considering heat transfer and FSI effects. • Higher convective heat transfer coefficient is beneficial for the FCI structural safety without much affect to bulk flow temperature. • Smaller FCI thermal conductivity can better prevent heat leakage into helium, yet will increase FCI temperature gradient and thermal stress. • Three-dimensional simulation on conjugate heat transfer in a fluid-structure coupled field was carried out

Analysis of flow induced vibration in heat exchangers

International Nuclear Information System (INIS)

Beek, A.W. van

1977-01-01

A description will be given of three different types of heat exchangers developed by the Dutch Nuclear Industry Group ''Neratoom'' in cooperation with TNO for the sodium-cooled fast breeder reactor SNR-300 at Kalkar. Moreover, the research related with flow induced vibrations carried out by TNO (Organization for Applied Scientific Research) will be presented. The flow induced forces on the tubes of the straight-tube steam generators were measured at the inlet and outlet section where partial crossflow occurs. With the measured flow induced forces the response of a tube was calculated as a function of the tube-to-supportbush clearances taking into account the non-linear damping effects from the sodium. The theoretical results showed that for this particular design no tube impact damage is to be expected which was confirmed later by a full scale experiment. Special attention will be devoted to the steam generator with helical-coil tube-bundles, where the sodium flows in a counter cross-flow over the tube-bundle. Extensive measurements of the power spectra of the flow induced forces were carried out since no information could be found in the literature. The vibration analysis will be presented and vibration modes of the entire bundle will be compared with experimentally obtained results. Finally a description of the vibration tests to be carried out on the intermediate heat exchanger (IHX) will be presented. (author)

Analysis of flow induced vibration in heat exchangers

Energy Technology Data Exchange (ETDEWEB)

Beek, A.W. van [Institute for Mechanical Constructions TNO, Delft (Netherlands)

1977-12-01

A description will be given of three different types of heat exchangers developed by the Dutch Nuclear Industry Group ''Neratoom'' in cooperation with TNO for the sodium-cooled fast breeder reactor SNR-300 at Kalkar. Moreover, the research related with flow induced vibrations carried out by TNO (Organization for Applied Scientific Research) will be presented. The flow induced forces on the tubes of the straight-tube steam generators were measured at the inlet and outlet section where partial crossflow occurs. With the measured flow induced forces the response of a tube was calculated as a function of the tube-to-supportbush clearances taking into account the non-linear damping effects from the sodium. The theoretical results showed that for this particular design no tube impact damage is to be expected which was confirmed later by a full scale experiment. Special attention will be devoted to the steam generator with helical-coil tube-bundles, where the sodium flows in a counter cross-flow over the tube-bundle. Extensive measurements of the power spectra of the flow induced forces were carried out since no information could be found in the literature. The vibration analysis will be presented and vibration modes of the entire bundle will be compared with experimentally obtained results. Finally a description of the vibration tests to be carried out on the intermediate heat exchanger (IHX) will be presented. (author)

Effect of Heating Method on Alteration of Protein Molecular Structure in Flaxseed: Relationship with Changes in Protein Subfraction Profile and Digestion in Dairy Cows.

Science.gov (United States)

Ahmad Khan, Nazir; Booker, Helen; Yu, Peiqiang

2015-02-04

This study evaluated the effect of heating methods on alteration of protein molecular structure in flaxseed (Linum usitatissimum L.) in relation to changes in protein subfraction profile and digestion in dairy cows. Seeds from two flaxseed varieties, sampled from two replicate plots at two locations, were evaluated. The seeds were either maintained in their raw state or heated in an air-draft oven (dry heating) or autoclave (moist heating) for 60 min at 120 °C or by microwave irradiation (MIR) for 5 min. Compared to raw seeds, moist heating decreased (P RUP) content (36.0 ± 5.19 to 46.9 ± 2.72% CP) and intestinal digestibility of RUP (61.0 ± 2.28 to 63.8 ± 2.67% RUP). Dry heating did not alter (P > 0.05) the protein subfraction profile and rumen degradation kinetics, whereas MIR increased (P RUP content from 36.0 ± 5.19 to 40.4 ± 4.67% CP. The MIR and dry heating did not alter (P > 0.05) the amide I to amide II ratio, but moist heating decreased (P RUP (R 2 = 0.71), and intestinal digestibility of RUP (R 2 = 0.72). Overall, heat-induced changes in protein nutritive value and digestion were strongly associated with heat-induced alteration in protein molecular structures.

Heat transfer in tube bundles of heat exchangers with flow baffles induced forced mixing

International Nuclear Information System (INIS)

AbuRomia, M.M.; Chu, A.W.; Cho, S.M.

1976-01-01

Thermal analysis of shell-and-tube heat exchangers is being investigated through geometric modeling of the unit configuration in addition to considering the heat transfer processes taking place within the tube bundle. The governing equations that characterize the heat transfer from the shell side fluid to the tube side fluid across the heat transfer tubewalls are indicated. The equations account for the heat transfer due to molecular conduction, turbulent thermal diffusion, and forced fluid mixing among various shell side fluid channels. The analysis, though general in principle, is being applied to the Clinch River Breeder Reactor Plant-Intermediate Heat Exchanger, which utilizes flow baffles appropriately designed for induced forced fluid mixing in the tube bundle. The results of the analysis are presented in terms of the fluid and tube wall temperature distributions of a non-baffled and baffled tube bundle geometry. The former case yields axial flow in the main bundle region while the latter is associated with axial/cross flow in the bundle. The radial components of the axial/cross flow yield the necessary fluid mixing that results in reducing the thermal unbalance among the heat transfer to the allowable limits. The effect of flow maldistribution, present on the tube or shell sides of the heat exchangers, in altering the temperature field of tube bundles is also noted

Mapping temperature-induced conformational changes in the Escherichia coli heat shock transcription factor sigma 32 by amide hydrogen exchange

DEFF Research Database (Denmark)

Rist, Wolfgang; Jørgensen, Thomas J D; Roepstorff, Peter

2003-01-01

Stress conditions such as heat shock alter the transcriptional profile in all organisms. In Escherichia coli the heat shock transcription factor, sigma 32, out-competes upon temperature up-shift the housekeeping sigma-factor, sigma 70, for binding to core RNA polymerase and initiates heat shock...... gene transcription. To investigate possible heat-induced conformational changes in sigma 32 we performed amide hydrogen (H/D) exchange experiments under optimal growth and heat shock conditions combined with mass spectrometry. We found a rapid exchange of around 220 of the 294 amide hydrogens at 37...... degrees C, indicating that sigma 32 adopts a highly flexible structure. At 42 degrees C we observed a slow correlated exchange of 30 additional amide hydrogens and localized it to a helix-loop-helix motif within domain sigma 2 that is responsible for the recognition of the -10 region in heat shock...

Enhanced heat sink with geometry induced wall-jet

Energy Technology Data Exchange (ETDEWEB)

Hossain, Md. Mahamudul, E-mail: sohel0991@gmail.com; Tikadar, Amitav; Bari, Fazlul; Morshed, A. K. M. M. [Department of Mechanical Engineering Bangladesh University of Engineering and Technology, Dhaka-1000. Bangladesh (Bangladesh)

2016-07-12

Mini-channels embedded in solid matrix have already proven to be a very efficient way of electronic cooling. Traditional mini-channel heat sinks consist of single layer of parallel channels. Although mini-channel heat sink can achieve very high heat flux, its pumping requirement for circulating liquid through the channel increase very sharply as the flow velocity increases. The pumping requirements of the heat sink can be reduced by increasing its performance. In this paper a novel approach to increase the thermal performance of the mini-channel heat sink is proposed through geometry induced wall jet which is a passive technique. Geometric irregularities along the channel length causes abrupt pressure change between the channels which causes cross flow through the interconnections thus one channel faces suction and other channel jet action. This suction and jet action disrupts boundary layer causing enhanced heat transfer performance. A CFD model has been developed using commercially available software package FLUENT to evaluate the technique. A parametric study of the velocities and the effect of the position of the wall-jets have been performed. Significant reduction in thermal resistance has been observed for wall-jets, it is also observed that this reduction in thermal resistance is dependent on the position and shape of the wall jet.

Continuous fever-range heat stress induces thermotolerance in odontoblast-lineage cells.

Science.gov (United States)

Morotomi, Takahiko; Kitamura, Chiaki; Okinaga, Toshinori; Nishihara, Tatsuji; Sakagami, Ryuji; Anan, Hisashi

2014-07-01

Heat shock during restorative procedures can trigger damage to the pulpodentin complex. While severe heat shock has toxic effects, fever-range heat stress exerts beneficial effects on several cells and tissues. In this study, we examined whether continuous fever-range heat stress (CFHS) has beneficial effects on thermotolerance in the rat clonal dental pulp cell line with odontoblastic properties, KN-3. KN-3 cells were cultured at 41°C for various periods, and the expression level of several proteins was assessed by Western blot analysis. After pre-heat-treatment at 41°C for various periods, KN-3 cells were exposed to lethal severe heat shock (LSHS) at 49°C for 10min, and cell viability was examined using the MTS assay. Additionally, the expression level of odontoblast differentiation makers in surviving cells was examined by Western blot analysis. CFHS increased the expression levels of several heat shock proteins (HSPs) in KN-3 cells, and induced transient cell cycle arrest. KN-3 cells, not pre-heated or exposed to CFHS for 1 or 3h, died after exposure to LSHS. In contrast, KN-3 cells exposed to CFHS for 12h were transiently lower on day 1, but increased on day 3 after LSHS. The surviving cells expressed odontoblast differentiation markers, dentine sialoprotein and dentine matrix protein-1. These results suggest that CFHS for 12h improves tolerance to LSHS by inducing HSPs expression and cell cycle arrest in KN-3 cells. The appropriate pretreatment with continuous fever-range heat stress can provide protection against lethal heat shock in KN-3 cells. Copyright © 2014 Elsevier Ltd. All rights reserved.

Heat pump processes induced by laser radiation

Science.gov (United States)

Garbuny, M.; Henningsen, T.

1980-01-01

A carbon dioxide laser system was constructed for the demonstration of heat pump processes induced by laser radiation. The system consisted of a frequency doubling stage, a gas reaction cell with its vacuum and high purity gas supply system, and provisions to measure the temperature changes by pressure, or alternatively, by density changes. The theoretical considerations for the choice of designs and components are dicussed.

Testosterone Depletion by Castration May Protect Mice from Heat-Induced Multiple Organ Damage and Lethality

Directory of Open Access Journals (Sweden)

Ruei-Tang Cheng

2010-01-01

Full Text Available When the vehicle-treated, sham-operated mice underwent heat stress, the fraction survival and core temperature at +4 h of body heating were found to be 5 of 15 and 34.4∘C±0.3∘C, respectively. Castration 2 weeks before the start of heat stress decreased the plasma levels of testosterone almost to zero, protected the mice from heat-induced death (fraction survival, 13/15 and reduced the hypothermia (core temperature, 37.3∘C. The beneficial effects of castration in ameliorating lethality and hypothermia can be significantly reduced by testosterone replacement. Heat-induced apoptosis, as indicated by terminal deoxynucleotidyl- transferase- mediatedαUDP-biotin nick end-labeling staining, were significantly prevented by castration. In addition, heat-induced neuronal damage, as indicated by cell shrinkage and pyknosis of nucleus, to the hypothalamus was also castration-prevented. Again, the beneficial effects of castration in reducing neuronal damage to the hypothalamus as well as apoptosis in multiple organs during heatstroke, were significantly reversed by testosterone replacement. The data indicate that testosterone depletion by castration may protect mice from heatstroke-induced multiple organ damage and lethality.

Excision of x-ray-induced thymine damage in chromatin from heated cells

International Nuclear Information System (INIS)

Warters, R.L.; Roti Roti, J.L.

1979-01-01

Experiments were performed to distinguish between two possible modes of hyperthermia-induced inhibition of thymine base damage excision from the DNA of CHO cells: (1) heat denaturation of excision enzyme(s) or (2) heat-induced alteration of the substrate for damage excision (chromatin). While hyperthermia (45 0 C, 15 min) had no apparent effect on the capacity of the excision enzymes to excise damage from DNA it had a dramatic effect (ca. 80% inhibition) on the ability of chromatin to serve as a substrate for unheated enzymes. These results suggest that hyperthermia-induced radiosensitization of CHO cells may be due primarily to lesions in the cellular chromatin

Effect of heating cast kafirin films on their functional properties

CSIR Research Space (South Africa)

Byaruhanga, YB

2007-01-01

Full Text Available of heated plasticized films showed more wrinkled structures compared to non-heated films, whereas the non-plasticized films appeared more brittle with heating. The results indicate that heat-induced intermolecular disulfide cross-linking was involved...

A Rice CaMBP Gene is Induced in Organ-Specific Manner by Both Chilling and Heat-Shock Treatments

Directory of Open Access Journals (Sweden)

Jia WAN

2008-09-01

Full Text Available A rice CaMBP gene, OsCaMBP (AB363406, was isolated from a chilling treated rice using the fluorescent differential display (FDD screening method. Its cDNA sequence (2094 bp contains an opening reading frame (ORF encoding a 569 amino acids protein (63.2 kD. OsCaMBP has the typical structural features of the CaMBP family, including the conserved IQ calmodulin-binding motif at the N-terminus. Homology analysis revealed 38.25%–47.28% identities of OsCaMBP with other CaMBPs in plants. RT-PCR analysis showed that the expression of OsCaMBP was remarkably inducible under the chilling (8°C and heat-shock (42°C treatments. OsCaMBP was undetectable under the normal conditions, and induced under the chilling treatment for 1 h, as well as the heat-shock treatment for 15 min, suggesting that the gene plays important roles in the signaling pathway in rice under both chilling and heat-shock stresses.

Influences of buoyancy and thermal boundary conditions on heat transfer with naturally-induced flow

International Nuclear Information System (INIS)

Jackson, J.D.; Li, J.

2002-01-01

A fundamental study is reported of heat transfer from a vertical heated tube to air which is induced naturally upwards through it by the action of buoyancy. Measurements of local heat transfer coefficient were made using a specially designed computer-controlled power supply and measurement system for conditions of uniform wall temperature and uniform wall heat flux. The effectiveness of heat transfer proved to be much lower than for conditions of forced convection. It was found that the results could be correlated satisfactorily when presented in terms of dimensionless parameters similar to those used for free convection heat transfer from vertical surfaces provided that the heat transfer coefficients were evaluated using local fluid bulk temperature calculated utilising the measured values of flow rate induced through the system. Additional experiments were performed' with pumped flow. These covered the entire mixed convection region. It was found that the data for naturally-induced flow mapped onto the pumped flow data when presented in terms of Nusselt number ratio (mixed to forced) and buoyancy parameter. Computational simulations of the experiments were performed using an advanced computer code which incorporated a buoyancy-influenced, variable property, developing wall shear flow formulation and a low Reynolds number k-ε turbulence model. These reproduced observed behaviour quite well. (author)

Development of structural design procedure of plate-fin heat exchanger for HTGR

Energy Technology Data Exchange (ETDEWEB)

Mizokami, Yorikata, E-mail: yorikata_mizokami@mhi.co.jp [Mitsubishi Heavy Industries, Ltd., 1-1, Wadasaki-cho 1-Chome, Hyogo-ku, Kobe 652-8585 (Japan); Igari, Toshihide [Mitsubishi Heavy Industries, Ltd., 5-717-1, Fukahori-machi, Nagasaki 851-0392 (Japan); Kawashima, Fumiko [Kumamoto University, 39-1 Kurokami 2-Chome, Kumamoto 860-8555 (Japan); Sakakibara, Noriyuki [Mitsubishi Heavy Industries, Ltd., 5-717-1, Fukahori-machi, Nagasaki 851-0392 (Japan); Tanihira, Masanori [Mitsubishi Heavy Industries, Ltd., 16-5, Konan 2-Chome, Minato-ku, Tokyo 108-8215 (Japan); Yuhara, Tetsuo [The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-8656 (Japan); Hiroe, Tetsuyuki [Kumamoto University, 39-1 Kurokami 2-Chome, Kumamoto 860-8555 (Japan)

2013-02-15

Highlights: ► We propose high temperature structural design procedure for plate-fin heat exchanger ► Allowable stresses for brazed structures will be newly discussed ► Validity of design procedure is confirmed by carrying out partial model tests ► Proposed design procedure is applied to heat exchangers for HTGR. -- Abstract: Highly efficient plate-fin heat exchanger for application to HTGR has been focused on recently. Since this heat exchanger is fabricated by brazing a lot of plates and fins, a new procedure for structural design of brazed structures in the HTGR temperature region up to 950 °C is required. Firstly in this paper influences on material strength due to both thermal aging during brazing process and helium gas environment were experimentally examined, and failure mode and failure limit of brazed side-bar structures were experimentally clarified. Secondly allowable stresses for aging materials and brazed structures were newly determined on the basis of the experimental results. For the purpose of validating the structural design procedure including homogenization FEM modeling, a pressure burst test and a thermal fatigue test of partial model for plate-fin heat exchanger were carried out. Finally, results of reference design of plate-fin heat exchangers of recuperator and intermediate heat exchanger for HTGR plant were evaluated by the proposed design criteria.

Selective activation of human heat shock gene transcription by nitrosourea antitumor drugs mediated by isocyanate-induced damage and activation of heat shock transcription factor.

Science.gov (United States)

Kroes, R A; Abravaya, K; Seidenfeld, J; Morimoto, R I

1991-01-01

Treatment of cultured human tumor cells with the chloroethylnitrosourea antitumor drug 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) selectively induces transcription and protein synthesis of a subset of the human heat shock or stress-induced genes (HSP90 and HSP70) with little effect on other stress genes or on expression of the c-fos, c-myc, or beta-actin genes. The active component of BCNU and related compounds appears to be the isocyanate moiety that causes carbamoylation of proteins and nucleic acids. Transcriptional activation of the human HSP70 gene by BCNU is dependent on the heat shock element and correlates with the level of heat shock transcription factor and its binding to the heat shock element in vivo. Unlike activation by heat or heavy metals, BCNU-mediated activation is strongly dependent upon new protein synthesis. This suggests that BCNU-induced, isocyanate-mediated damage to newly synthesized protein(s) may be responsible for activation of the heat shock transcription factor and increased transcription of the HSP90 and HSP70 genes. Images PMID:2052560

Heat-induced electron emission in paraelectric phase of triglycine sulfate heated with great rate

CERN Document Server

Sidorkin, A A; Rogazinskaya, O V; Milovidova, S D

2002-01-01

One recorded experimentally heat-induced electron emission in ferroelectric triglycine sulfate (TGS) crystal within temperature range exceeding the Curie point by 10-15 K. One studied cases of q = dT/dt various rates of linear heating of specimens of TGS nominally pure crystal and TGS crystal with chromium impurity. Increase of heating rate is shown to result in increase of emission current density within the whole investigated range of temperatures. Temperature of emission occurrence depends on q rate negligibly. At the same time, temperature of emission disappearance monotonically increases with q growth. At q below 1 K/min it is localized below the Curie point. At q = 4-5 K/min the mentioned temperature reaches 60-65 deg C. In TGS crystal with chromium impurity the temperature of emission occurrence is close to the case of pure TGS. In this case, the range of emission drawing in paraphase here is by about 2 times narrower in contrast to the case of pure TGS heated with the same rate

Loop Heat Pipe Temperature Oscillation Induced by Gravity Assist and Reservoir Heating

Science.gov (United States)

Ku, Jentung; Garrison, Matt; Patel, Deepak; Robinson, Frank; Ottenstein, Laura

2015-01-01

The Laser Thermal Control System (LCTS) for the Advanced Topographic Laser Altimeter System (ATLAS) to be installed on NASA's Ice, Cloud, and Land Elevation Satellite (ICESat-2) consists of a constant conductance heat pipe and a loop heat pipe (LHP) with an associated radiator. During the recent thermal vacuum testing of the LTCS where the LHP condenser/radiator was placed in a vertical position above the evaporator and reservoir, it was found that the LHP reservoir control heater power requirement was much higher than the analytical model had predicted. Even with the control heater turned on continuously at its full power, the reservoir could not be maintained at its desired set point temperature. An investigation of the LHP behaviors found that the root cause of the problem was fluid flow and reservoir temperature oscillations, which led to persistent alternate forward and reversed flow along the liquid line and an imbalance between the vapor mass flow rate in the vapor line and liquid mass flow rate in the liquid line. The flow and temperature oscillations were caused by an interaction between gravity and reservoir heating, and were exacerbated by the large thermal mass of the instrument simulator which modulated the net heat load to the evaporator, and the vertical radiator/condenser which induced a variable gravitational pressure head. Furthermore, causes and effects of the contributing factors to flow and temperature oscillations intermingled.

Analysis of laser-induced heating in optical neuronal guidance

DEFF Research Database (Denmark)

Ebbesen, Christian L.; Bruus, Henrik

2012-01-01

Recently, it has been shown that it is possible to control the growth direction of neuronal growth cones by stimulation with weak laser light; an effect dubbed optical neuronal guidance. The effect exists for a broad range of laser wavelengths, spot sizes, spot intensities, optical intensity...... profiles and beam modulations, but it is unknown which biophysical mechanisms govern it. Based on thermodynamic modeling and simulation using published experimental parameters as input, we argue that the guidance is linked to heating. Until now, temperature effects due to laser-induced heating...

Heat-induced whey protein isolate fibrils: Conversion, hydrolysis, and disulphide bond formation

NARCIS (Netherlands)

Bolder, S.G.; Vasbinder, A.; Sagis, L.M.C.; Linden, van der E.

2007-01-01

Fibril formation of individual pure whey proteins and whey protein isolate (WPI) was studied. The heat-induced conversion of WPI monomers into fibrils at pH 2 and low ionic strength increased with heating time and protein concentration. Previous studies, using a precipitation method, size-exclusion

Structural analysis of heat-treated birch (Betule papyrifera) surface during artificial weathering

International Nuclear Information System (INIS)

Huang Xianai; Kocaefe, Duygu; Kocaefe, Yasar; Boluk, Yaman; Krause, Cornélia

2013-01-01

Highlights: ► Investigate detailed structural changes of heat-treated wood due to weathering. ► Identify connection between physical structural changes and chemical degradation. ► Study effect of heat treatment conditions on weathering degradation process. - Abstract: Effect of artificial weathering on the surface structural changes of birch (Betule papyrifera) wood, heat-treated to different temperatures, was studied using the fluorescence microscopy and the scanning electron microscopy (SEM). Changes in the chemical structure of wood components were analyzed by FTIR in order to understand the mechanism of degradation taking place due to heat treatment and artificial weathering. The results are compared with those of the untreated (kiln-dried) birch. The SEM analysis results show that the effect of weathering on the cell wall of the untreated birch surface is more than that of heat-treated samples. The FTIR spectroscopy results indicate that lignin is the most sensitive component of heat-treated birch to the weathering degradation process. Elimination of the amorphous and highly crystallised cellulose is observed for both heat-treated and untreated wood during weathering. It is also observed that heat treatment increases the lignin and crystallised cellulose contents, which to some extent protects heat-treated birch against degradation due to weathering.

Heat Stress-Induced PI3K/mTORC2-Dependent AKT Signaling Is a Central Mediator of Hepatocellular Carcinoma Survival to Thermal Ablation Induced Heat Stress.

Directory of Open Access Journals (Sweden)

Scott M Thompson

Full Text Available Thermal ablative therapies are important treatment options in the multidisciplinary care of patients with hepatocellular carcinoma (HCC, but lesions larger than 2-3 cm are plagued with high local recurrence rates and overall survival of these patients remains poor. Currently no adjuvant therapies exist to prevent local HCC recurrence in patients undergoing thermal ablation. The molecular mechanisms mediating HCC resistance to thermal ablation induced heat stress and local recurrence remain unclear. Here we demonstrate that the HCC cells with a poor prognostic hepatic stem cell subtype (Subtype HS are more resistant to heat stress than HCC cells with a better prognostic hepatocyte subtype (Subtype HC. Moreover, sublethal heat stress rapidly induces phosphoinositide 3-kinase (PI3K/mammalian target of rapamycin (mTOR dependent-protein kinase B (AKT survival signaling in HCC cells in vitro and at the tumor ablation margin in vivo. Conversely, inhibition of PI3K/mTOR complex 2 (mTORC2-dependent AKT phosphorylation or direct inhibition of AKT function both enhance HCC cell killing and decrease HCC cell survival to sublethal heat stress in both poor and better prognostic HCC subtypes while mTOR complex 1 (mTORC1-inhibition has no impact. Finally, we showed that AKT isoforms 1, 2 and 3 are differentially upregulated in primary human HCCs and that overexpression of AKT correlates with worse tumor biology and pathologic features (AKT3 and prognosis (AKT1. Together these findings define a novel molecular mechanism whereby heat stress induces PI3K/mTORC2-dependent AKT survival signaling in HCC cells and provide a mechanistic rationale for adjuvant AKT inhibition in combination with thermal ablation as a strategy to enhance HCC cell killing and prevent local recurrence, particularly at the ablation margin.

Palm kernel cake extract exerts hepatoprotective activity in heat-induced oxidative stress in chicken hepatocytes.

Science.gov (United States)

Oskoueian, Ehsan; Abdullah, Norhani; Idrus, Zulkifli; Ebrahimi, Mahdi; Goh, Yong Meng; Shakeri, Majid; Oskoueian, Armin

2014-10-02

Palm kernel cake (PKC), the most abundant by-product of oil palm industry is believed to contain bioactive compounds with hepatoprotective potential. These compounds may serve as hepatoprotective agents which could help the poultry industry to alleviate adverse effects of heat stress on liver function in chickens. This study was performed to evaluate the hepatoprotective potential of PKC extract in heat-induced oxidative stress in chicken hepatocytes. The nature of the active metabolites and elucidation of the possible mechanism involved were also investigated. The PKC extract possessed free radical scavenging activity with values significantly (p < 0.05) lower than silymarin as the reference antioxidant. Heat-induced oxidative stress in chicken hepatocyte impaired the total protein, lipid peroxidation and antioxidant enzymes activity significantly (p < 0.05). Treatment of heat-induced hepatocytes with PKC extract (125 μg/ml) and silymarin as positive control increased these values significantly (p < 0.05). The real time PCR and western blot analyses revealed the significant (p < 0.05) up-regulation of oxidative stress biomarkers including TNF-like, IFN-γ and IL-1β genes; NF-κB, COX-2, iNOS and Hsp70 proteins expression upon heat stress in chicken hepatocytes. The PKC extract and silymarin were able to alleviate the expression of all of these biomarkers in heat-induced chicken hepatocytes. The gas chromatography-mass spectrometry analysis of PKC extract showed the presence of fatty acids, phenolic compounds, sugar derivatives and other organic compounds such as furfural which could be responsible for the observed hepatoprotective activity. Palm kernel cake extract could be a potential agent to protect hepatocytes function under heat induced oxidative stress.

Metal-insulator transition upon heating and negative-differential-resistive-switching induced by self-heating in BaCo{sub 0.9}Ni{sub 0.1}S{sub 1.8}

Energy Technology Data Exchange (ETDEWEB)

Fisher, B.; Genossar, J.; Chashka, K. B.; Patlagan, L.; Reisner, G. M. [Physics Department, Technion-Israel Institute of Technology, Haifa 32000 (Israel)

2014-04-14

The layered compound BaCo{sub 1−x}Ni{sub x}S{sub 2−y} (0.05 < x < 0.2 and 0.05 < y < 0.2) exhibits an unusual first-order structural and electronic phase transition from a low-T monoclinic paramagnetic metal to a high-T tetragonal antiferromagnetic insulator around 200 K with huge hysteresis (∼40 K) and large volume change (∼0.01). Here, we report on unusual voltage-controlled resistive switching followed by current-controlled resistive switching induced by self-heating in polycrystalline BaCo{sub 1−x}Ni{sub x}S{sub 2−y} (nominal x = 0.1 and y = 0.2). These were due to the steep metal to insulator transition upon heating followed by the activated behavior of the resistivity above the transition. The major role of Joule heating in switching is supported by the absence of nonlinearity in the current as function of voltage, I(V), obtained in pulsed measurements, in the range of electric fields relevant to d.c. measurements. The voltage-controlled negative differential resistance around the threshold for switching was explained by a simple model of self-heating. The main difficulty in modeling I(V) from the samples resistance as function of temperature R(T) was the progressive increase of R(T), and to a lesser extend the decrease of the resistance jumps at the transitions, caused by the damage induced by cycling through the transitions by heating or self-heating. This was dealt with by following systematically R(T) over many cycles and by using the data of R(T) in the heating cycle closest to that of the self-heating one.

Spin Heat Accumulation Induced by Tunneling from a Ferromagnet

NARCIS (Netherlands)

Vera-Marun, I.J.; Wees, B.J. van; Jansen, R.

2014-01-01

An electric current from a ferromagnet into a nonmagnetic material can induce a spin-dependent electron temperature. Here, it is shown that this spin heat accumulation, when created by tunneling from a ferromagnet, produces a non-negligible voltage signal that is comparable to that due to the

Group constant preparation for the estimate of neutron induced damage in structural materials

International Nuclear Information System (INIS)

Panini, G.C.

1996-01-01

Neutron heating (kerma), displacement per atom cross sections (DPA), gas and γ-ray production are important parameters for the estimate of the damage produced by neutron induced nuclear reactions in the structural materials. The NJOY System for Nuclear Data Processing has been extensively used in order to compute the above quantities; here the theory, the algorithms and the connected problems are described. (author). 6 refs, 3 tabs

Ion track membranes providing heat pipe surfaces with capillary structures

International Nuclear Information System (INIS)

Akapiev, G.N.; Dmitriev, S.N.; Erler, B.; Shirkova, V.V.; Schulz, A.; Pietsch, H.

2003-01-01

The microgalvanic method for metal filling of etched ion tracks in organic foils is of particular interest for the fabrication of microsized structures. Microstructures like copper whiskers with a high aspect ratio produced in ion track membranes are suitable for the generation of high-performance heat transfer surfaces. A surface with good heat transfer characteristics is defined as a surface on which a small temperature difference causes a large heat transfer from the surface material to the liquid. It is well-known that a porous surface layer transfers to an evaporating liquid a given quantity of heat at a smaller temperature difference than does a usual smooth surface. Copper whiskers with high aspect ratio and a density 10 5 per cm 2 form such a porous structure, which produces strong capillary forces and therefore a maximum of heat transfer coefficients

Theoretical study of orbital ordering induced structural phase transition in iron pnictides

Energy Technology Data Exchange (ETDEWEB)

Jena, Sushree Sangita, E-mail: sushree@iopb.res.in; Rout, G. C., E-mail: gcr@iopb.res.in [Physics Enclave, Plot No-664/4825, Lane-4A, Shree Vihar, Bhubaneswar-24, Odisha (India); Panda, S. K., E-mail: skp@iopb.res.in

2016-05-06

We attribute the structural phase transition (SPT) in the parent compounds of the iron pnictides to orbital ordering. Due to anisotropy of the d{sub xz} and d{sub yz} orbitals in the xy plane, orbital ordering makes the orthorhombic structure more favorable and thus inducing the SPT. We consider a one band model Hamiltonian consisting of first and second-nearest-neighbor hopping of the electrons. We introduce Jahn-Tellar (JT) distortion in the system arising due to the orbital ordering present in this system. We calculate the electron Green’s function by using Zuvareb’s Green’s function technique and hence calculate an expression for the temperature dependent lattice strain which is computed numerically and self-consistently. The temperature dependent electron specific heat is calculated by minimizing the free energy of the system. The lattice strain is studied by varying the JT coupling and elastic constant of the system. The structural anomaly is studied through the electron occupation number and the specific heat by varying the physical parameters like JT coupling, lattice constant, chemical potential and hopping integrals of the system.

The social structure of heat consumption in Denmark

DEFF Research Database (Denmark)

Hansen, Anders Rhiger

2016-01-01

The role of households in relation to heat and energy consumption has been well-described in both quantitative and qualitative studies. However, where practice theory has developed as the main theoretical framework within qualitative studies on energy consumption, the more recent quantitative...... of the qualitative studies, emphasising how energy consumption is a result of energy-consuming practices. Focusing on heat consumption used for space heating and heating of water in single-family detached houses in Denmark, it is found that sociocultural differences between households such as income, education......, occupation, and immigration status influence the amount of heat consumed by a household; directly as an indicator of household practices and indirectly through type of building and household characteristics. New interpretations based on theories of practice show that factors such as the social structure...

Rheological and structural properties of sea cucumber Stichopus japonicus during heat treatment

Science.gov (United States)

Gao, Xin; Xue, Dongmei; Zhang, Zhaohui; Xu, Jiachao; Xue, Changhu

2005-07-01

Changes in tissue structure, rheological properties and water content of raw and heated sea cucumber meat were studied. Sea cucumber Stichopus japonicus was heated at 25°C , 70°C and 100°C water for 5 min. The structural changes were observed using a light microscope and the rheological parameters (rupture strength, adhesive strength and deformation) determined using a texture meter. Microscopic photograph revealed that the structural change of heated meat was greater than that of raw meat. The rupture strength, adhesive strength and deformation of raw meat were smaller than those of the heated meat. Meanwhile, rheological parameters showed positive correlation with heating temperature. These changes are mainly caused by thermal denaturation and gelatinization of collagen during heating. These changes were also evidenced in observations using a light microscope and differential scanning calorimetry.

Improvement of boiling heat transfer by radiation induced boiling enhancement

International Nuclear Information System (INIS)

Imai, Yasuyuki; Okamoto, Koji; Madarame, Haruki; Takamasa, Tomoji

2003-01-01

For nuclear reactor systems, the critical heat flux (CHF) data is very important because it limits reactor efficiency. Improvement of CHF requires that the cooling liquid can contact the heating surface, or a high-wettability, highly hydrophilic heating surface, even if a vapor bubble layer is generated on the surface. In our previous study, we confirmed that the surface wettability changed significantly or that highly hydrophilic conditions were achieved, after irradiation of 60 Co gamma ray, by the Radiation Induced Surface Activation (RISA) phenomenon. To delineate the effect of RISA on boiling phenomena, surface wettability in a high-temperature environment and critical heat flux (CHF) of metal oxides irradiated by gamma rays were investigated. A CHF experiment in the pool boiling condition was carried out under atmospheric pressure. The heating test section made of titanium was 0.2 mm in thickness, 3 mm in height, and 60 mm in length. Oxidation of the surface was carried out by plasma jetting for 40 seconds. The test section was irradiated by 60 Co gamma ray with predetermined radiation intensity and period. The CHF of oxidized titanium was improved up to 100 percent after 800 kGy 60 Co gamma ray irradiation. We call this effect Radiation Induced Boiling Enhancement (RIBE). Before we conducted the CHF experiment, contact angles of the test pieces were measured to show the relationship between wettability and CHF. The CHF in the present experiment increases will surface wettability in the same manner as shown by Liaw and Dhir's results. (author)

Improvement of boiling heat transfer by radiation induced boiling enhancement

International Nuclear Information System (INIS)

Imai, Y.; Okamoto, K.; Madarame, H.; Takamasa, T.

2003-01-01

For nuclear reactor systems, the Critical Heat Flux (CHF) data is very important because it limits reactor efficiency. Improvement of CHF requires that the cooling liquid can contact the heating surface, or a high-wettability, highly hydrophilic heating surface, even if a vapor bubble layer is generated on the surface. In our previous study, we confirmed that the surface wettability changed significantly or that highly hydrophilic conditions were achieved, after irradiation of 60Co gamma ray, by the Radiation Induced Surface Activation (RISA) phenomenon. To delineate the effect of RISA on boiling phenomena, surface wettability in a high-temperature environment and Critical Heat Flux (CHF) of metal oxides irradiated by gamma rays were investigated. A CHF experiment in the pool boiling condition was carried out under atmospheric pressure. The heating test section made of titanium was 0.2mm in thickness, 3mm in height, and 60mm in length. Oxidation of the surfaces was carried out by plasma jetting for 40 seconds. The test section was irradiated by 60Co gamma ray with predetermined radiation intensity and period. The CHF of oxidized titanium was improved up to 100 percent after 800kGy 60Co gamma ray irradiation. We call this effect Radiation Induced Boiling Enhancement (RIBE). Before we conducted the CHF experiment, contact angles of the test pieces were measured to show the relationship between wettability and CHF. The CHF in the present experiment increases with surface wettability in the same manner as shown by Liaw and Dhir's results

Structural transformations of heat-treated bacterial iron oxide

Energy Technology Data Exchange (ETDEWEB)

Hashimoto, Hideki, E-mail: hideki-h@cc.okayama-u.ac.jp [Graduate School of Natural Science and Technology, Okayama University, Okayama 700-8530 (Japan); JST, CREST, Okayama 700-8530 (Japan); Fujii, Tatsuo [Graduate School of Natural Science and Technology, Okayama University, Okayama 700-8530 (Japan); Kohara, Shinji [Japan Synchrotron Radiation Research Institute, Sayo, Hyogo 679-5198 (Japan); Nakanishi, Koji [Office of Society-Academia Collaboration for Innovation, Kyoto University, Uji 611-0011 (Japan); Yogi, Chihiro [SR Center, Ritsumeikan University, Kusatsu, Shiga 525-8577 (Japan); Peterlik, Herwig [Faculty of Physics, University of Vienna, A-1090 Vienna (Austria); Nakanishi, Makoto [Graduate School of Natural Science and Technology, Okayama University, Okayama 700-8530 (Japan); Takada, Jun [Graduate School of Natural Science and Technology, Okayama University, Okayama 700-8530 (Japan); JST, CREST, Okayama 700-8530 (Japan)

2015-04-01

A bacterial siliceous iron oxide microtubule (diameter: ca. 1 μm, 15Fe{sub 2}O{sub 3}·8SiO{sub 2}·P{sub 2}O{sub 5}·30H{sub 2}O) produced by Leptothrix ochracea was heat treated in air and its structural transformation was investigated in detail by microscopy, diffractometry, and spectroscopy. Although the heat-treated bacterial iron oxide retained its original microtubular structure, its nanoscopic, middle-range, and local structures changed drastically. Upon heat treatment, nanosized pores were formed and their size changed depending on temperature. The Fe–O–Si linkages were gradually cleaved with increasing temperature, causing the progressive separation of Fe and Si ions into iron oxide and amorphous silicate phases, respectively. Concomitantly, global connectivity and local structure of FeO{sub 6} octahedra in the iron oxide nanoparticles systematically changed depending on temperature. These comprehensive investigations clearly revealed various structural changes of the bacterial iron oxide which is an important guideline for the future exploration of novel bio-inspired materials. - Highlights: • Structural transformation of a bacterial iron oxide microtubule was investigated. • Si–O–Fe was cleaved with increasing temperature to form α-Fe{sub 2}O{sub 3}/silicate composite. • Crystallization to 2Fh started at 500 °C to give α-Fe{sub 2}O{sub 3} >700 °C. • FeO{sub 6} octahedra were highly distorted <500 °C. • Formation of face-sharing FeO{sub 6} was promoted >500 °C, releasing the local strain of FeO{sub 6}.

Beam-induced heating / bunch length / RF and lessons for 2012

International Nuclear Information System (INIS)

Metral, E.

2012-01-01

Beam-induced heating has been observed here and there during the 2011 run when the bunch/beam intensity was increased and/or the bunch length was reduced. These observations are first reviewed before mentioning the recent news/work performed during the shutdown. In fact, several possible sources of heating exist and only the RF heating (i.e. coming from the real part of the longitudinal impedance of the machine components) is discussed in some detail in the present paper: 1) comparing the case of a Broad-Band (BB) vs. a Narrow-Band (NB) impedance; 2) discussing the beam spectrum; 3) reminding the usual solutions to avoid/minimize the RF heating; 4) reviewing the different heat transfer mechanisms; 5) mentioning that the synchronous phase shift is a measurement of the power loss and effective impedance. The three current 'hot' topics for the LHC performance, which are the VMTSA, TDI and MKI, are then analyzed in detail and some lessons for 2012 (and after) are finally drawn

The structural design of the experimental equipment for unconventional heating water using heat transfer surfaces located in the heat source

Directory of Open Access Journals (Sweden)

Jandačka J.

2013-04-01

Full Text Available Flue gas temperature at throat of most industrially produced fireplaces is around 250 to 350 °C. It's quite interesting thermal potential, which can be even before sucking up the chimney back utilize. One of the potential uses of this device to heat the hot water. Article refers to the structural design of such a device, which works with the transfer of heat through a substance changes phase from liquid to steam in a sealed tube (heat pipe. Benefits of heat pipes is their light weight, the thermal effect of a rapid and low maintenance costs.

The structural design of the experimental equipment for unconventional heating water using heat transfer surfaces located in the heat source

Science.gov (United States)

Kaduchová, K.; Lenhard, R.; Gavlas, S.; Jandačka, J.

2013-04-01

Flue gas temperature at throat of most industrially produced fireplaces is around 250 to 350 °C. It's quite interesting thermal potential, which can be even before sucking up the chimney back utilize. One of the potential uses of this device to heat the hot water. Article refers to the structural design of such a device, which works with the transfer of heat through a substance changes phase from liquid to steam in a sealed tube (heat pipe). Benefits of heat pipes is their light weight, the thermal effect of a rapid and low maintenance costs.

Heat-Induced, Pressure-Induced and Centrifugal-Force-Induced Exact Axisymmetric Thermo-Mechanical Analyses in a Thick-Walled Spherical Vessel, an Infinite Cylindrical Vessel, and a Uniform Disk Made of an Isotropic and Homogeneous Material

Directory of Open Access Journals (Sweden)

Vebil Yıldırım

2017-07-01

Full Text Available Heat-induced, pressure-induced, and centrifugal force-induced axisymmetric exact deformation and stresses in a thick-walled spherical vessel, a cylindrical vessel, and a uniform disk are all determined analytically at a specified constant surface temperature and at a constant angular velocity. The inner and outer pressures are both included in the formulation of annular structures made of an isotropic and homogeneous linear elastic material. Governing equations in the form of Euler-Cauchy differential equation with constant coefficients are solved and results are presented in compact forms. For disks, three different boundary conditions are taken into account to consider mechanical engineering applications. The present study is also peppered with numerical results in graphical forms.

Structures for handling high heat fluxes

International Nuclear Information System (INIS)

Watson, R.D.

1990-01-01

The divertor is recognized as one of the main performance limiting components for ITER. This paper reviews the critical issues for structures that are designed to withstand heat fluxes >5 MW/m 2 . High velocity, sub-cooled water with twisted tape inserts for enhanced heat transfer provides a critical heat flux limit of 40-60 MW/m 2 . Uncertainties in physics and engineering heat flux peaking factors require that the design heat flux not exceed 10 MW/m 2 to maintain an adequate burnout safety margin. Armor tiles and heat sink materials must have a well matched thermal expansion coefficient to minimize stresses. The divertor lifetime from sputtering erosion is highly uncertain. The number of disruptions specified for ITER must be reduced to achieve a credible design. In-situ plasma spray repair with thick metallic coatings may reduce the problems of erosion. Runaway electrons in ITER have the potential to melt actively cooled components in a single event. A water leak is a serious accident because of steam reactions with hot carbon, beryllium, or tungsten that can mobilize large amounts of tritium and radioactive elements. If the plasma does not shutdown immediately, the divertor can melt in 1-10 s after a loss of coolant accident. Very high reliability of carbon tile braze joints will be required to achieve adequate safety and performance goals. Most of these critical issues will be addressed in the near future by operation of the Tore Supra pump limiters and the JET pumped divertor. An accurate understanding of the power flow out of edge of a DT burning plasma is essential to successful design of high heat flux components. (orig.)

Temperature rise and stress induced by microcracks in accelerating structures

Directory of Open Access Journals (Sweden)

W. Zhu

2010-12-01

Full Text Available The temperature rise and induced stress due to Ohmic heating in the vicinity of microcracks on the walls of high-gradient accelerating structures are considered. The temperature rise and induced stress depend on the orientation of the crack with respect to the rf magnetic field, the shape of the crack, and the power and duration of the rf pulse. Under certain conditions the presence of cracks can double the temperature rise over that of a smooth surface. Stress at the bottom of the cracks can be several times larger than that of the case when there are no cracks. We study these effects both analytically and by computer simulation. It is shown that the stress in cracks is maximal when the crack depth is on the order of the thermal penetration depth.

Fast switching of alkali atom dispensers using laser-induced heating

International Nuclear Information System (INIS)

Griffin, P.F.; Weatherill, K.J.; Adams, C.S.

2005-01-01

We show that by using an intense laser source to locally heat an alkali atom dispenser, one can generate a high flux of atoms followed by fast recovery (<100 ms) of the background pressure when the laser is extinguished. For repeated heating pulses a switch-on time for the atomic flux of 200 ms is readily attainable. This technique is suited to ultracold atom experiments using simple ultrahigh vacuum (UHV) chambers. Laser-induced heating provides a fast repetition of the experimental cycle, which, combined with low atom loss due to background gas collisions, is particularly useful for experiments involving far-off resonance optical traps, where sufficient laser power (0.5-4 W) is readily available

Heat deposition on the first wall due to ICRF-induced loss of fast ions in JT-60U

International Nuclear Information System (INIS)

Kusama, Y.; Tobita, K.; Kimura, H.; Hamamatsu, K.; Fujii, T.; Nemoto, M.; Saigusa, M.; Moriyama, S.; Tani, K.; Koide, Y.; Sakasai, A.; Nishitani, T.; Ushigusa, K.

1995-01-01

In JT-60U, the heat deposition on the first wall due to the ICRF-induced loss of fast ions was investigated by changing the position of the resonance layer in the ripple-trapping region. A heat spot appears on the first wall of the same major radius as the resonance layer of the ICRF waves. The broadening of the heat spot in the major radius direction is consistent with that of the resonance layer due to the Doppler broadening. The heat spot is considered to be formed by the ICRF-induced ripple-trapped loss of fast ions. Although the total ICRF-induced loss power to the heat spot is as low as 2% of the total ICRF power, the additional heat flux will become a new issue because of the localized heat deposition on the first wall. ((orig.))

Structural transformations of heat treated Co-less high entropy alloys

Science.gov (United States)

Mitrica, D.; Tudor, A.; Rinaldi, A.; Soare, V.; Predescu, C.; Berbecaru, A.; Stoiciu, F.; Badilita, V.

2018-03-01

Co is considered to be one of the main ingredients in superalloys. Co is considered a critical element and its substitution is difficult due to its unique ability to form high temperature stable structures with high mechanical and corrosion/oxidation resistance. High entropy alloys (HEA) represent a relatively new concept in material design. HEA are characterised by a high number of alloying elements, in unusually high proportion. Due to their specific particularities, high entropy alloys tend to form predominant solid solution structures that develop potentially high chemical, physical and mechanical properties. Present paper is studying Co-less high entropy alloys with high potential in severe environment applications. The high entropy alloys based on Al-Cr-Fe-Mn-Ni system were prepared by induction melting and casting under protective atmosphere. The as-cast specimens were heat treated at various temperatures to determine the structure and property behaviour. Samples taken before and after heat treatment were investigated for chemical, physical, structural and mechanical characteristics. Sigma phase composition and heat treatment parameters had major influence over the resulted alloy structure and properties.

Planetary-scale circulations in the presence of climatological and wave-induced heating

Science.gov (United States)

Salby, Murry L; Garcia, Rolando R.; Hendon, Harry H.

1994-01-01

Interaction between the large-scale circulation and the convective pattern is investigated in a coupled system governed by the linearized primitive equations. Convection is represented in terms of two components of heating: A 'climatological component' is prescribed stochastically to represent convection that is maintained by fixed distributions of land and sea and sea surface temperature (SST). An 'induced component' is defined in terms of the column-integrated moisture flux convergence to represent convection that is produced through feedback with the circulation. Each component describes the envelope organizing mesoscale convective activity. As SST on the equator is increased, induced heating amplifies in the gravest zonal wavenumbers at eastward frequencies, where positive feedback offsets dissipation. Under barotropic stratification, a critical SST of 29.5 C results in positive feedback exactly cancelling dissipation in wavenumber 1 for an eastward phase speed of 6 m/s. Sympathetic interaction between the circulation and the induced heating is the basis for 'frictional wave-Conditional Instability of the Second Kind (CISK)', which is distinguished from classical wave-CISK by rendering the gravest zonal dimensions most unstable. Under baroclinic stratification, the coupled system exhibits similar behavior. The critical SST is only 26.5 C for conditions representative of equinox, but in excess of 30 C for conditions representative of solstice. Having the form of an unsteady Walker circulation, the disturbance produced by frictional wave-CISK compares favorably with the observed life cycle of the Madden-Julian oscillation (MJO). SST above the critical value produces an amplifying disturbance in which enhanced convection coincides with upper-tropospheric westerlies and is positively correlated with temperature and surface convergence. Conversely, SST below the critical value produces a decaying disturbance in which enhanced convection coincides with upper

Structural, mechanical and light yield characterisation of heat treated LYSO:Ce single crystals for medical imaging applications

Energy Technology Data Exchange (ETDEWEB)

Mengucci, P., E-mail: p.mengucci@univpm.it [Università Politecnica delle Marche, Via Brecce Bianche, 60131 Ancona (Italy); André, G. [Laboratoire Léon Brillouin, CEA-CNRS, CE-Saclay, 91191 Gif sur Yvette cedex (France); Auffray, E. [Department PH-CMX CERN, Route de Meyrin, 1211 Geneva 23 (Switzerland); Barucca, G. [Università Politecnica delle Marche, Via Brecce Bianche, 60131 Ancona (Italy); Cecchi, C. [Dipartimento di Fisica e Geologia, Università di Perugia, Via A. Pascoli, 06123 Perugia (Italy); Chipaux, R. [CEA DSM/IRFU/SEDI, CE-Saclay, 91191 Gif sur Yvette cedex (France); Cousson, A. [Laboratoire Léon Brillouin, CEA-CNRS, CE-Saclay, 91191 Gif sur Yvette cedex (France); Davì, F. [Università Politecnica delle Marche, Via Brecce Bianche, 60131 Ancona (Italy); Di Vara, N. [Department PH-CMX CERN, Route de Meyrin, 1211 Geneva 23 (Switzerland); Rinaldi, D.; Santecchia, E. [Università Politecnica delle Marche, Via Brecce Bianche, 60131 Ancona (Italy)

2015-06-11

Five single crystals of cerium-doped lutetium yttrium oxyorthosilicate (LYSO:Ce) grown by the Czochralski method were submitted to structural characterisation by X-ray (XRD) and neutron (ND) diffraction, scanning (SEM) and transmission (TEM) electron microscopy and energy dispersive microanalysis (EDS). The Ultimate Tensile Strength (UTS), the Young Modulus (YM) and the Light Yield (LY) of the samples were also measured in order to correlate the mechanical and the optical behaviour of the crystals with the characteristics of their microstructure. Two of the samples analysed were also heat treated at 300 °C for 10 h to evidence possible variations induced by the temperature in the optical and mechanical response of the crystals. Results showed that the mean compositional variations evidenced by the structural analyses do not affect the mechanical and optical behaviour of the samples. On the contrary, the thermal treatment could induce the formation of coherent spherical particles (size 10 to 15 nm), not uniformly distributed inside the sample, that strongly reduce the UTS and YM values, but it does not affect the optical response of the crystal. This latter result was attributed to the low value of the heating temperature (300 °C) that is not sufficiently high to induce annealing of the oxygen vacancies traps that are responsible of the deterioration of the scintillation properties of the LYSO:Ce crystals. This study was carried out in the framework of the Crystal Clear Collaboration (CCC)

Calculation of the kinetics of heating and structural changes in the cartilaginous tissue under the action of laser radiation

International Nuclear Information System (INIS)

Sobol', E N; Kitai, M S

1998-01-01

A theoretical model is developed for the calculation of the temperature fields and determination of the size of a zone with structural changes in the cartilaginous tissue. The model is based on a simultaneous analysis of the heat and mass transfer processes and it takes into account the bulk absorption of laser radiation by the tissue, surface evaporation of water, and temperature dependences of the diffusion coefficients. It is assumed that under the influence of a phase transition between free and bound water, caused by heating of the cartilage to 70 0 C, the proteoglycans of the cartilage matrix become mobile and, as a result of such mass transfer, structural changes are induced in the cartilaginous tissue causing relaxation of stresses or denaturation. It is shown that the maximum temperature is then reached not on the irradiated surface but at some distance from it, and that the size of the zones of structural changes (denaturation depth) depends strongly on the energy density of the laser radiation and its wavelength, on the duration of the irradiation, and on the cartilage thickness. This model makes it possible to calculate the temperature fields and the depth of structural changes in laser-induced relaxation of stresses and changes in the shape of the cartilaginous tissue. (interaction of laser radiation with matter)

Oncostatin M induces heat hypersensitivity by gp130-dependent sensitization of TRPV1 in sensory neurons

Directory of Open Access Journals (Sweden)

Langeslag Michiel

2011-12-01

Full Text Available Abstract Oncostatin M (OSM is a member of the interleukin-6 cytokine family and regulates eg. gene activation, cell survival, proliferation and differentiation. OSM binds to a receptor complex consisting of the ubiquitously expressed signal transducer gp130 and the ligand binding OSM receptor subunit, which is expressed on a specific subset of primary afferent neurons. In the present study, the effect of OSM on heat nociception was investigated in nociceptor-specific gp130 knock-out (SNS-gp130-/- and gp130 floxed (gp130fl/fl mice. Subcutaneous injection of pathophysiologically relevant concentrations of OSM into the hind-paw of C57BL6J wild type mice significantly reduced paw withdrawal latencies to heat stimulation. In contrast to gp130fl/fl mice, OSM did not induce heat hypersensitivity in vivo in SNS-gp130-/- mice. OSM applied at the receptive fields of sensory neurons in in vitro skin-nerve preparations showed that OSM significantly increased the discharge rate during a standard ramp-shaped heat stimulus. The capsaicin- and heat-sensitive ion channel TRPV1, expressed on a subpopulation of nociceptive neurons, has been shown to play an important role in inflammation-induced heat hypersensitivity. Stimulation of cultured dorsal root ganglion neurons with OSM resulted in potentiation of capsaicin induced ionic currents. In line with these recordings, mice with a null mutation of the TRPV1 gene did not show any signs of OSM-induced heat hypersensitivity in vivo. The present data suggest that OSM induces thermal hypersensitivity by directly sensitizing nociceptors via OSMR-gp130 receptor mediated potentiation of TRPV1.

CELLS OVEREXPRESSING HSP27 SHOW ACCELERATED RECOVERY FROM HEAT-INDUCED NUCLEAR-PROTEIN AGGREGATION

NARCIS (Netherlands)

KAMPINGA, HH; BRUNSTING, JF; STEGE, GJJ; KONINGS, AWT; LANDRY, J

1994-01-01

Protein denaturation/aggregation upon cell exposure to heat shock is a likely cause of cell death. in the nucleus, protein aggregation has often been correlated to inhibition of nuclear located processes and heat-induced cell killing. in Chinese hamster 023 cells made thermotolerant by a prior

Effects of nanoparticle heating on the structure of a concentrated aqueous salt solution.

Science.gov (United States)

Sindt, Julien O; Alexander, Andrew J; Camp, Philip J

2017-12-07

The effects of a rapidly heated nanoparticle on the structure of a concentrated aqueous salt solution are studied using molecular dynamics simulations. A diamond-like nanoparticle of radius 20 Å is immersed in a sodium-chloride solution at 20% above the experimental saturation concentration and equilibrated at T = 293 K and P = 1 atm. The nanoparticle is then rapidly heated to several thousand degrees Kelvin, and the system is held under isobaric-isoenthalpic conditions. It is observed that after 2-3 ns, the salt ions are depleted far more than water molecules from a proximal zone 15-25 Å from the nanoparticle surface. This leads to a transient reduction in molality in the proximal zone and an increase in ion clustering in the distal zone. At longer times, ions begin to diffuse back into the proximal zone. It is speculated that the formation of proximal and distal zones, and the increase in ion clustering, plays a role in the mechanism of nonphotochemical laser-induced nucleation.

Effects of nanoparticle heating on the structure of a concentrated aqueous salt solution

Science.gov (United States)

Sindt, Julien O.; Alexander, Andrew J.; Camp, Philip J.

2017-12-01

The effects of a rapidly heated nanoparticle on the structure of a concentrated aqueous salt solution are studied using molecular dynamics simulations. A diamond-like nanoparticle of radius 20 Å is immersed in a sodium-chloride solution at 20% above the experimental saturation concentration and equilibrated at T = 293 K and P = 1 atm. The nanoparticle is then rapidly heated to several thousand degrees Kelvin, and the system is held under isobaric-isoenthalpic conditions. It is observed that after 2-3 ns, the salt ions are depleted far more than water molecules from a proximal zone 15-25 Å from the nanoparticle surface. This leads to a transient reduction in molality in the proximal zone and an increase in ion clustering in the distal zone. At longer times, ions begin to diffuse back into the proximal zone. It is speculated that the formation of proximal and distal zones, and the increase in ion clustering, plays a role in the mechanism of nonphotochemical laser-induced nucleation.

Assessment of flow induced vibration in a sodium-sodium heat exchanger

Energy Technology Data Exchange (ETDEWEB)

Prakash, V. [Fast Reactor Technology Group, Indira Gandhi Centre for Atomic Research, Kalpakkam, Tamil Nadu (India)], E-mail: prakash@igcar.gov.in; Thirumalai, M.; Prabhakar, R.; Vaidyanathan, G. [Fast Reactor Technology Group, Indira Gandhi Centre for Atomic Research, Kalpakkam, Tamil Nadu (India)

2009-01-15

The 500 MWe Prototype Fast Breeder Reactor (PFBR) is under construction at Kalpakkam. It is a liquid metal sodium cooled pool type fast reactor with all primary components located inside a sodium pool. The heat produced due to fission in the core is transported by primary sodium to the secondary sodium in a sodium to sodium Intermediate Heat Exchanger (IHX), which in turn is transferred to water in the steam generator. PFBR IHX is a shell and tube type heat exchanger with primary sodium on shell side and secondary sodium in the tube side. Since IHX is one of the critical components placed inside the radioactive primary sodium, trouble-free operation of the IHX is very much essential for power plant availability. To validate the design and the adequacy of the support system provided for the IHX, flow induced vibration (FIV) experiments were carried out in a water test loop on a 60 deg. sector model. This paper discusses the flow induced vibration measurements carried out in 60 deg. sector model of IHX, the modeling criteria, the results and conclusion.

Transient, heat-induced thermal resistance in the small intestine of mouse

International Nuclear Information System (INIS)

Hume, S.P.; Marigold, J.C.L.

1980-01-01

Heat-induced thermal resistance has been investigated in mouse jejunum by assaying crypt survival 24 h after treatment. Hyperthermia was achieved by immersing an exteriorized loop of intestine in a bath of Krebs-Ringer solution. Two approaches have been used. In the first, thermal survival curves were obtained following single hyperthermal treatments at temperatures in the range 42 to 44 0 C. Transient thermal resistance, inducted by a plateau in the crypt survival curve, developed during heating at temperatures around 42.5 0 C after 60 to 80 min. In the second series of experiments, a priming heat treatment (40.0, 41.0, 41.5, or 42.0 0 C for 60 min) was followed at varying intervals by a test treatment at 43.0 0 C. A transient resistance to the second treatment was induced, the extent and time of development being dependent upon the priming treatment. Crypt survival curves for thermally resistant intestine showed an increase in thermal D 0 and a decrease in n compared with curves from previously unheated intestine

Effect of heat treatment on structure and magnetic properties

Indian Academy of Sciences (India)

Fe46Co35Ni19/CNTs nanocomposites have been prepared by an easy two-step route including adsorption and heat treatment processes. We investigated the effect of heat treatment conditions on structure, morphology, nanoparticle sizes and magnetic properties of the Fe46Co35Ni19 alloy nanoparticles attached on the ...

ELM induced divertor heat loads on TCV

Energy Technology Data Exchange (ETDEWEB)

Marki, J., E-mail: janos.marki@epfl.c [Centre de Recherches en Physique des Plasmas (CRPP), Ecole Polytechnique Federale de Lausanne (EPFL), Association Euratom - Confederation Suisse, CH-1015 Lausanne (Switzerland); Pitts, R.A. [Centre de Recherches en Physique des Plasmas (CRPP), Ecole Polytechnique Federale de Lausanne (EPFL), Association Euratom - Confederation Suisse, CH-1015 Lausanne (Switzerland); Horacek, J. [Institute of Plasma Physics, Association EUROATOM-IPP.CR, Za Slovankou 3, 182 00 Prague 8 (Czech Republic); Tskhakaya, D. [Association EURATOM-OAW, Institut fuer Theoretische Physik, A-6020 Innsbruck (Austria)

2009-06-15

Results are presented for heat loads at the TCV outer divertor target during ELMing H-mode using a fast IR camera. Benefitting from a recent surface cleaning of the entire first wall graphite armour, a comparison of the transient thermal response of freshly cleaned and untreated tile surfaces (coated with thick co-deposited layers) has been performed. The latter routinely exhibit temperature transients exceeding those of the clean ones by a factor approx3, even if co-deposition throughout the first days of operation following the cleaning process leads to the steady regrowth of thin layers. Filaments are occasionally observed during the ELM heat flux rise phase, showing a spatial structure consistent with energy release at discrete toroidal locations in the outer midplane vicinity and with individual filaments carrying approx1% of the total ELM energy. The temporal waveform of the ELM heat load is found to be in good agreement with the collisionless free streaming particle model.

ELM induced divertor heat loads on TCV

Science.gov (United States)

Marki, J.; Pitts, R. A.; Horacek, J.; Tskhakaya, D.; TCV Team

2009-06-01

Results are presented for heat loads at the TCV outer divertor target during ELMing H-mode using a fast IR camera. Benefitting from a recent surface cleaning of the entire first wall graphite armour, a comparison of the transient thermal response of freshly cleaned and untreated tile surfaces (coated with thick co-deposited layers) has been performed. The latter routinely exhibit temperature transients exceeding those of the clean ones by a factor ˜3, even if co-deposition throughout the first days of operation following the cleaning process leads to the steady regrowth of thin layers. Filaments are occasionally observed during the ELM heat flux rise phase, showing a spatial structure consistent with energy release at discrete toroidal locations in the outer midplane vicinity and with individual filaments carrying ˜1% of the total ELM energy. The temporal waveform of the ELM heat load is found to be in good agreement with the collisionless free streaming particle model.

Structural analysis of osseous rests exposed to heating

International Nuclear Information System (INIS)

Medina, C.; Tiesler, V.; Quintana, P.; Oliva, A.I.

2005-01-01

Heat exposed human remains present physical and chemical changes that, when analysed, may provide important indications about the type of heating they were exposed. This information, jointly with that of the archaeological context, allows us to know about the cultural practices of the past from a methodological perspective that actually, has not been explored sufficiently. The present investigation applies a series of structural parameters of bone in the evaluation of skeletal sample from the archaeological site of Calakmul, which exhibits signs of thermal exposure. Results on the Pre hispanic specimens are compared to those obtained from an experimental series of animal bone, which was submitted to different types of heat with the objective to contribute with new data on the forms of heating and their role in ancient Maya society. (Author)

Myowater dynamics and protein secondary structural changes as affected by heating rate in three pork qualities: a combined FT-IR microspectroscopic and 1H NMR relaxometry study.

Science.gov (United States)

Wu, Zhiyun; Bertram, Hanne Christine; Böcker, Ulrike; Ofstad, Ragni; Kohler, Achim

2007-05-16

The objective of this study was to investigate the influence of heating rate on myowater dynamics and protein secondary structures in three pork qualities by proton NMR T2 relaxation and Fourier transform infrared (FT-IR) microspectroscopy measurements. Two oven temperatures at 100 degrees C and 200 degrees C corresponding to slow and fast heating rates were applied on three pork qualities (DFD, PSE, and normal) to an internal center temperature of 65 degrees C. The fast heating induced a higher cooking loss, particularly for PSE meat. The water proton T21 distribution representing water entrapped within the myofibrillar network was influenced by heating rate and meat quality. Fast heating broadened the T21 distribution and decreased the relaxation times of the T21 peak position for three meat qualities. The changes in T21 relaxation times in meat can be interpreted in terms of chemical and diffusive exchange. FT-IR showed that fast heating caused a higher gain of random structures and aggregated beta-sheets at the expense of native alpha-helixes, and these changes dominate the fast-heating-induced broadening of T21 distribution and reduction in T21 times. Furthermore, of the three meat qualities, PSE meat had the broadest T21 distribution and the lowest T21 times for both heating rates, reflecting that the protein aggregation of PSE caused by heating is more extensive than those of DFD and normal, which is consistent with the IR data. The present study demonstrated that the changes in T2 relaxation times of water protons affected by heating rate and raw meat quality are well related to the protein secondary structural changes as probed by FT-IR microspectroscopy.

Influence of mutations in some structural genes of heat-shock proteins on radiation resistance of Escherichia coli

International Nuclear Information System (INIS)

Verbenko, V.N.; Kuznetsova, L.V.; Bikineeva, E.G.; Kalinin, V.L.

1992-01-01

Lethal effects of γ-irradiation were studied in Escherichia coli strains with normal repair genotype and in radiation-resistant Gam r strains, both carrying additional mutations in the structural genes dnaK, grpE, groES or groEL. The null mutation ΔdnaK52::Cm r enhanced radiation sensitivity of wild-type cells and abolished the effect of heat induced rediation-resistance (ETIRR) and elevated radiation resistance of the Gam r strains

The decrease in the IgG-binding capacity of intensively dry heated whey proteins is associatead with intense Maillard reaction, structural changes of the proteins and formation of RAGE-ligands

NARCIS (Netherlands)

Liu, F.; Teodorowicz, M.; Boekel, van M.A.J.S.; Wichers, H.J.; Hettinga, K.A.

2016-01-01

Heat treatment is the most common way of milk processing, inducing structural changes as well as chemical modifications in milk proteins. These modifications influence the immune-reactivity and allergenicity of milk proteins. This study shows the influence of dry heating on the solubility, particle

Phenylephrine-induced elevations in arterial blood pressure are attenuated in heat-stressed humans

Science.gov (United States)

Cui, Jian; Wilson, Thad E.; Crandall, Craig G.

2002-01-01

To test the hypothesis that phenylephrine-induced elevations in blood pressure are attenuated in heat-stressed humans, blood pressure was elevated via steady-state infusion of three doses of phenylephrine HCl in 10 healthy subjects in both normothermic and heat stress conditions. Whole body heating significantly increased sublingual temperature by 0.5 degrees C, muscle sympathetic nerve activity (MSNA), heart rate, and cardiac output and decreased total peripheral vascular resistance (TPR; all P blood pressure (MAP; P > 0.05). At the highest dose of phenylephrine, the increase in MAP and TPR from predrug baselines was significantly attenuated during the heat stress [DeltaMAP 8.4 +/- 1.2 mmHg; DeltaTPR 0.96 +/- 0.85 peripheral resistance units (PRU)] compared with normothermia (DeltaMAP 15.4 +/- 1.4 mmHg, DeltaTPR 7.13 +/- 1.18 PRU; all P blood pressure, as well as the slope of the relationship between heart rate and systolic blood pressure, respectively, was similar between thermal conditions (each P > 0.05). These data suggest that phenylephrine-induced elevations in MAP are attenuated in heat-stressed humans without affecting baroreflex control of MSNA or heart rate.

Development of micro-structured heat exchangers; Developpement d'echangeurs de chaleur microstructures

Energy Technology Data Exchange (ETDEWEB)

Bouzon, C

2004-10-01

This study has been carried out to defend the Technological Diploma of Research, in the aim to develop micro-structured heat exchangers. Realized within the Research Group on the Heat exchangers and Energy (GREThE) of the Atomic Energy Commission (CEA) of Grenoble. The rise of micro-technologies and the optimization of heat exchangers have led to emergence from few years of new structures of fluid paths with scales lower than the millimeter, thus making it possible to produce heat exchangers ultra-compacts. The micro-structured exchangers are heat exchangers whose hydraulic diameters are lower than the millimeter but with external dimensions of several centimeters. The study is based on two patents filed by the CEA and the characterization of these two geometries. A first concept of cross flow type finds applications with Gas/Liquid heat exchanger. A second type, a countercurrent, is more adapted to Liquid/Liquid applications. An approach with simplified analytical models and by numerical simulation was employed for each concept. An experimental study on the Gas/Liquid concept was also carried out. (author)

Heat-Induced Changes in Heat Shock Protein Genes Expression in Crossbred and Baladi Pregnant Cows and Their Offspring

International Nuclear Information System (INIS)

Khalil, W.K.B.; Nessim, M.Z.; El- Masry, K.A.

2010-01-01

The experiment was carried out during August (hot climate) on twelve pregnant cows of six crossbred (50% native Baladi and 50% Brown Swiss) and six native Baladi pregnant cows in the same age and the second parity during their mid-pregnancy as detected by rectal palpation. The experiment was repeated during December (mild climate) on similar twelve pregnant cows. Blood sample was obtained from each cow at the end of August (first group) and at the end of December (second group) to obtain heat shock protein genes expression (HSP72, HSP70.01, HSP70, HSP47, k Dalton and Actin) in pregnant cows under mild and hot climate to find out, which breed is more tolerant to heat stress and to estimate offspring birth weight and their growth performances during suckling period. Comparison was made between hot climate cows group and mild climate cows group to estimate heat- induced changes in both breeds in expression level of the Hsp genes and to compare with their neonate birth weight and growth performances during suckling period. The results revealed that expression level of the Hsp genes (Hsp72, Hsp70.1, Hsp70 and Hsp 47) was higher (p<0.01) in hot season compared to that of mild season. Expression level of the Hsp genes (Hsp70.1, Hsp70 and Hsp 47) was higher (p<0.05) in crossbred cows than in Baldi cows under summer hot season. This indicates that crossbred cows are less heat tolerant than Baladi cows under heat stress climate. Heat induced decrease (p<0.01) in offspring birth weight in Baladi and crossbred by 18.1% and 25%, respectively, in weaning weight by 14.61% and 23.14%, respectively and in body weight gain by 14.61% and 21.18%, respectively

Micro-structured rough surfaces by laser etching for heat transfer enhancement on flush mounted heat sinks

International Nuclear Information System (INIS)

Ventola, L; Scaltrito, L; Ferrero, S; Chiavazzo, E; Asinari, P; Maccioni, G

2014-01-01

The aim of this work is to improve heat transfer performances of flush mounted heat sinks used in electronic cooling. To do this we patterned 1.23 cm 2 heat sinks surfaces by microstructured roughnesses built by laser etching manufacturing technique, and experimentally measured the convective heat transfer enhancements due to different patterns. Each roughness differs from the others with regards to the number and the size of the micro-fins (e.g. the micro- fin length ranges from 200 to 1100 μm). Experimental tests were carried out in forced air cooling regime. In particular fully turbulent flows (heating edge based Reynolds number ranging from 3000 to 17000) were explored. Convective heat transfer coefficient of the best micro-structured heat sink is found to be roughly two times compared to the smooth heat sinks one. In addition, surface area roughly doubles with regard to smooth heat sinks, due to the presence of micro-fins. Consequently, patterned heat sinks thermal transmittance [W/K] is found to be roughly four times the smooth heat sinks one. We hope this work may open the way for huge boost in the technology of electronic cooling by innovative manufacturing techniques.

An Induction Heating Method with Traveling Magnetic Field for Long Structure Metal

Science.gov (United States)

Sekine, Takamitsu; Tomita, Hideo; Obata, Shuji; Saito, Yukio

A novel dismantlable adhesion method for recycling operation of interior materials is proposed. This method is applied a high frequency induction heating and a thermoplastic adhesive. For an adhesion of interior material to long steel stud, a conventional spiral coil as like IH cooking heater gives inadequateness for uniform heating to the stud. Therefore, we have proposed an induction heating method with traveling magnetic field for perfect long structures bonding. In this paper, we describe on the new adhesion method using the 20kHz, three-phase 200V inverter and linear induction coil. From induction heating characteristics to thin steel plates and long studs, the method is cleared the usefulness for uniform heating to long structures.

Model techniques for testing heated concrete structures

International Nuclear Information System (INIS)

Stefanou, G.D.

1983-01-01

Experimental techniques are described which may be used in the laboratory to measure strains of model concrete structures representing to scale actual structures of any shape or geometry, operating at elevated temperatures, for which time-dependent creep and shrinkage strains are dominant. These strains could be used to assess the distribution of stress in the scaled structure and hence to predict the actual behaviour of concrete structures used in nuclear power stations. Similar techniques have been employed in an investigation to measure elastic, thermal, creep and shrinkage strains in heated concrete models representing to scale parts of prestressed concrete pressure vessels for nuclear reactors. (author)

Influence of heat and shear induced protein aggregation on the in vitro digestion rate of whey proteins.

Science.gov (United States)

Singh, Tanoj K; Øiseth, Sofia K; Lundin, Leif; Day, Li

2014-11-01

Protein intake is essential for growth and repair of body cells, the normal functioning of muscles, and health related immune functions. Most food proteins are consumed after undergoing various degrees of processing. Changes in protein structure and assembly as a result of processing impact the digestibility of proteins. Research in understanding to what extent the protein structure impacts the rate of proteolysis under human physiological conditions has gained considerable interest. In this work, four whey protein gels were prepared using heat processing at two different pH values, 6.8 and 4.6, with and without applied shear. The gels showed different protein network microstructures due to heat induced unfolding (at pH 6.8) or lack of unfolding, thus resulting in fine stranded protein networks. When shear was applied during heating, particulate protein networks were formed. The differences in the gel microstructures resulted in considerable differences in their rheological properties. An in vitro gastric and intestinal model was used to investigate the resulting effects of these different gel structures on whey protein digestion. In addition, the rate of digestion was monitored by taking samples at various time points throughout the in vitro digestion process. The peptides in the digesta were profiled using SDS-polyacrylamide gel electrophoresis, reversed-phase-HPLC and LC-MS. Under simulated gastric conditions, whey proteins in structured gels were hydrolysed faster than native proteins in solution. The rate of peptides released during in vitro digestion differed depending on the structure of the gels and extent of protein aggregation. The outcomes of this work highlighted that changes in the network structure of the protein can influence the rate and pattern of its proteolysis under gastrointestinal conditions. Such knowledge could assist the food industry in designing novel food formulations to control the digestion kinetics and the release of biologically

Prostaglandins with antiproliferative activity induce the synthesis of a heat shock protein in human cells

International Nuclear Information System (INIS)

Santoro, M.G.; Garaci, E.; Amici, C.

1989-01-01

Prostaglandins (PGs)A 1 and J 2 were found to potently suppress the proliferation of human K562 erythroleukemia cells and to induce the synthesis of a 74-kDa protein (p74) that was identified as a heat shock protein related to the major 70-kDa heat shock protein group. p74 synthesis was stimulated at doses of PGA 1 and PGJ 2 that inhibited cell replication, and its accumulation ceased upon removal of the PG-induced proliferation block. PGs that did not affect K562 cell replication did not induce p74 synthesis. p74 was found to be localized mainly in the cytoplasm of PG-treated cells, but moderate amounts were found also in dense areas of the nucleus after PGJ 2 treatment. p74 was not necessarily associated with cytotoxicity or with inhibition of cell protein synthesis. The results described support the hypothesis that synthesis of the 70-kDa heat shock proteins is associated with changes in cell proliferation. The observation that PGs can induce the synthesis of heat shock proteins expands our understanding of the mechanism of action of these compounds whose regulatory role is well known in many physiological phenomena, including the control of fever production

Pool boiling characteristics and critical heat flux mechanisms of microporous surfaces and enhancement through structural modification

Science.gov (United States)

Ha, Minseok; Graham, Samuel

2017-08-01

Experimental studies have shown that microporous surfaces induce one of the highest enhancements in critical heat flux (CHF) during pool boiling. However, microporous surfaces may also induce a very large surface superheat (>100 °C) which is not desirable for applications such as microelectronics cooling. While the understanding of the CHF mechanism is the key to enhancing boiling heat transfer, a comprehensive understanding is not yet available. So far, three different theories for the CHF of microporous surfaces have been suggested: viscous-capillary model, hydrodynamic instability model, and dryout of the porous coatings. In general, all three theories account for some aspects of boiling phenomena. In this study, the theories are examined through their correlations with experimental data on microporous surfaces during pool boiling using deionized (DI) water. It was found that the modulation of the vapor-jet through the pore network enables a higher CHF than that of a flat surface based on the hydrodynamic instability theory. In addition, it was found that as the heat flux increases, a vapor layer grows in the porous coatings described by a simple thermal resistance model which is responsible for the large surface superheat. Once the vapor layer grows to fill the microporous structure, transition to film boiling occurs and CHF is reached. By disrupting the formation of this vapor layer through the fabrication of channels to allow vapor escape, an enhancement in the CHF and heat transfer coefficient was observed, allowing CHF greater than 3500 kW/m2 at a superheat less than 50 °C.

Heat treatment giving a stable high temperature micro-structure in cast austenitic stainless steel

Science.gov (United States)

Anton, Donald L.; Lemkey, Franklin D.

1988-01-01

A novel micro-structure developed in a cast austenitic stainless steel alloy and a heat treatment thereof are disclosed. The alloy is based on a multicomponent Fe-Cr-Mn-Mo-Si-Nb-C system consisting of an austenitic iron solid solution (.gamma.) matrix reinforced by finely dispersed carbide phases and a heat treatment to produce the micro-structure. The heat treatment includes a prebraze heat treatment followed by a three stage braze cycle heat treatment.

heat-induced biological changes as heat tolerance indices related to growth performance in buffaloes

International Nuclear Information System (INIS)

Kaldes, M.Z.N.

2004-01-01

the main objective of this study was to predict new heat tolerance indices related to hot summer growth performance, depending on heat - induced changes in some physiological and biochemical parameters of young water buffalo calves. the present study was carried out on 8 egyptian male buffalo calves of 6 months old and 106.8 kg mean body weight (B W), and on the same animals of 12 months old and 179.5 kg mean B W. the animals were maintained in a climatic chamber of the egyptian atomic energy authority. the animals were maintained in metabolic cages inside a climatic chamber for 3 weeks under mild climate (20-24 c and 50-60% Rh, equivalent to 62-72 THI) for 6 hours daily as adjustment period,followed by 5 and 7 days in the 6- and 12-month old calves, respectively at the same climatic conditions as a control period.this was followed by 6 hours of acute heat exposure period (33-43 c and 40-60% Rh, equivalent to 85-93 Thi), then by chronic heat exposure period of the same climatic conditions for 5 and 7 days in the 6- and 12- month old calves, respectively.Rectal temperature (RT) and respiration rate (RR) were estimated daily, whereas BW was estimated at the beginning and the end of each exposure period

Structural assessment of intermediate printed circuit heat exchanger for sodium-cooled fast reactor with supercritical CO2 cycle

International Nuclear Information System (INIS)

Lee, Youho; Lee, Jeong Ik

2014-01-01

Highlights: • We numerically model PCHE stress arising from pressure, and thermal loadings. • Stress levels are the highest around S-CO 2 channels, due to high pressure of S-CO 2 . • The conventional analytic models for PCHE underestimate actual stress levels. • Plasticity sufficiently lowers stress levels at channel tips. • PCHE for SFR-SCO 2 is anticipated to assure compliance with ASME design standards. - Abstract: Structural integrity of intermediate Printed Circuit Heat Exchanger (PCHE) for Sodium-cooled Fast Reactor (SFR) attached to Supercritical CO 2 (S-CO 2 ) is investigated. ANSYS-Mechanical was used to simulate stress fields of representative PCHE channels, with temperature fields imported from FLUENT simulation. Mechanical stress induced by pressure loading is found to be the primary source of stress. As plasticity sufficiently lowers local stress concentration at PCHE channel tips, PCHE type intermediate heat exchangers made of SS316 are anticipated to reliably assure compliance with design standards prescribed in the ASME standards, thanks to the structure temperature that is below the effective creep inducing point. The actual life time of PCHE for SFR-SCO 2 is likely to be affected by mechanical behavior change of SS316 with reactions with S-CO 2 and fatigue

Crystal structure of a small heat-shock protein from Xylella fastidiosa reveals a distinct high-order structure.

Science.gov (United States)

Fonseca, Emanuella Maria Barreto; Scorsato, Valéria; Dos Santos, Marcelo Leite; Júnior, Atilio Tomazini; Tada, Susely Ferraz Siqueira; Dos Santos, Clelton Aparecido; de Toledo, Marcelo Augusto Szymanski; de Souza, Anete Pereira; Polikarpov, Igor; Aparicio, Ricardo

2017-04-01

Citrus variegated chlorosis is a disease that attacks economically important citrus plantations and is caused by the plant-pathogenic bacterium Xylella fastidiosa. In this work, the structure of a small heat-shock protein from X. fastidiosa (XfsHSP17.9) is reported. The high-order structures of small heat-shock proteins from other organisms are arranged in the forms of double-disc, hollow-sphere or spherical assemblies. Unexpectedly, the structure reported here reveals a high-order architecture forming a nearly square cavity.

Structure of fast shocks in the presence of heat conduction

International Nuclear Information System (INIS)

Tsai, C. L.; Chen, H. H.; Wu, B. H.; Lee, L. C.

2007-01-01

There are three types of magnetohydrodynamic (MHD) shocks: the fast shock, intermediate shock, and slow shock. The structure of slow shocks and intermediate shocks in the presence of heat conduction has been studied earlier [C. L. Tsai, R. H. Tsai, B. H. Wu, and L. C. Lee, Phys. Plasmas 9, 1185 (2002); C. L. Tsai, B. H. Wu, and L. C. Lee, Phys. Plasmas 12, 82501 (2005)]. Based on one-dimensional MHD numerical simulations with a heat conduction term, the evolution and structure of fast shocks are studied. The fast shock will form a foreshock in the presence of heat conduction. The foreshock is formed due to the heat flow from downstream to upstream and located in the immediate upstream of the main shock. In the steady state, the value of diffusion velocity V d in the foreshock is found to nearly equal the upstream convection velocity in the fast shock frame. It is found that the density jump across the main shock in high Mach number case can be much larger than 4 in the early simulation time. However the density jump will gradually evolve to a value smaller than 4 at steady state. By using the modified Rankine-Hugoniot relations with heat flux, the density jump across the fast shock is examined for various upstream parameters. The results show that the calculated density jump with heat flux is very close to the simulation value and the density jump can far exceed the maximum value of 4 without heat conduction. The structure of foreshock and main shock is also studied under different plasma parameters, such as the heat conductivity K 0 , the ratio of upstream plasma pressure to magnetic pressure β 1 , Alfven Mach number M A1 , and the angle θ 1 between shock normal and magnetic field. It is found that as the upstream shock parameters K 0 , β 1 , and M A1 increase or θ 1 decreases, the width of foreshock L d increases. The present results can be applied to fast shocks in the solar corona, solar wind, and magnetosphere, in which the heat conduction effects are

Differences in heat-induced cell killing as determined in three mammalian cell lines do not correspond with the extent of heat radiosensitization

International Nuclear Information System (INIS)

Kampinga, H.H.; Jorritsma, J.B.M.; Burgman, P.; Konings, A.W.T.

1986-01-01

Three different cell lines, Ehrlich ascites tumour (EAT) cells, HeLa S 3 cells and LM mouse fibroblasts, were used to investigate whether or not the extent of heat killing (44 0 C) and heat radio-sensitization (44 0 C before 0-6 Gy X-irradiation) are related. Although HeLa cells were the most heat-resistant cell line and showed the least heat radiosensitization, we found that the most heat-sensitive EAT cells (D 0 , EAT = 8.0 min; D 0 , LM = 10.0 min; D 0 , HeLa = 12.5 min) showed less radiosensitization than the more heat-resistant LM fibroblasts (TERsub(HeLa)< TERsub(EAT)< TERsub(LM)). Therefore, it is concluded that the routes leading to heat-induced cell death are not identical to those determining heat radiosensitization. Furthermore the inactivation of DNA polymerase α and β activities by heat seemed not to correlate with heat survival alone but showed a positive relationship to heat radiosensitization. The possibility of these enzymes being a determinant in heat radiosensitization is discussed. (author)

Heating of microprotrusions in accelerating structures

Directory of Open Access Journals (Sweden)

A. C. Keser

2013-09-01

Full Text Available The thermal and field emission of electrons from protrusions on metal surfaces is a possible limiting factor on the performance and operation of high-gradient room temperature accelerator structures. We present here the results of extensive numerical simulations of electrical and thermal behavior of protrusions. We unify the thermal and field emission in the same numerical framework, describe bounds for the emission current and geometric enhancement, then we calculate the Nottingham and Joule heating terms and solve the heat equation to characterize the thermal evolution of emitters under rf electric field. Our findings suggest that heating is entirely due to the Nottingham effect. The time dependence of the rf field leads to a time dependent tip temperature with excursion that depends weakly on rf frequency. We build a phenomenological model to account for the effect of space charge and show that space charge eliminates the possibility of copper tip melting for tips with radii less than 10  μm with vacuum fields on their surface less than 12  GV/m, and for rf frequencies above 1 GHz.

Comparison of the heat shock response induced by conventional heating and two methods of delivery of pulsed radiofrequency energy

International Nuclear Information System (INIS)

Laurence, J.A.; University of Sydney, NSW; McKenzie, D.R.; Veas, L.; French, P.W.

2002-01-01

Full text: In 2001, we published a (hypothetical) mechanism by which radiofrequency (RF) radiation from mobile phones could induce cancer, via the chronic induction of the heat shock response (HSR). This hypothesis provides the focus for our research. Other groups have reported induction of the HSR by RF at apparently non thermal levels. The aim of this study was to determine whether the HSR induced by RF is (a) truly non thermal and (b) quantitatively or qualitatively different from that induced by conventional heating of cells. A rat mast cell line, RBL-2H3, was chosen as the target RBL-2H3 cells were exposed in an air incubator at 41.1 deg C for 45 minutes and 75 minutes, and then returned to a 37 deg C incubator. Sham exposures were performed in the same air incubator at 37 deg C. Cells were exposed for 1 hour in the two pulsed RF exposure systems. The first was a converted 750W microwave oven that emits a short burst of 2.45GHz pulses at the start of each contiguous six minute period. This exposes cells to an average specific energy absorption rate (SAR) of 20W/kg. The second system was a TEM cell, which simulates. GSM pulses - the earner frequency is 0.9GHz pulse modulated at 217Hz. The SAR was approx 0.1W/kg. Both of these exposure systems are housed in incubators maintained at 37 deg C. Sham exposures were performed in the two systems with the same conditions but with no RF radiation present. Cell samples for the conventional heating and microwave exposures were taken 0, 2. 5, 5 and 20 hours after exposure, and expression of heat shock proteins hsp 110, 90, 70, 60 and 56 were determined by Western Blotting and compared between exposures

Vortex structure behind highly heated two cylinders in parallel arrangements

International Nuclear Information System (INIS)

Kurita, Eiichirou; Yahagi, Yuji

2008-01-01

Vortex structures behind twin, highly heated cylinders in parallel arrangements have been investigated experimentally. The experiments were conducted under the following conditions: cylinder diameter, D=4 mm; mean flow velocity, U ∞ =1.0 m/s; Reynolds number, Re=250; cylinder clearance, S/D=0.5 - 1.4; and cylinder heat flux, q=0 - 72.6 kW/m 2 . For S/D > 1.2, the Karman vortex street is formed alternately behind each cylinder divided on the slit flow. The slit flow velocity increases with a decrease in S/D and decreases with increasing heat flux. For S/D 2 ). As a result, the increased local kinematic viscosity and S/D play a key role for the vortex structure and formation behind arrangements of two parallel cylinders. (author)

Nerve growth factor induces facial heat hyperalgesia and plays a role in trigeminal neuropathic pain in rats.

Science.gov (United States)

Dos Reis, Renata C; Kopruszinski, Caroline M; Nones, Carina F M; Chichorro, Juliana G

2016-09-01

There is preclinical evidence that nerve growth factor (NGF) contributes toward inflammatory hyperalgesia in the orofacial region, but the mechanisms underlying its hyperalgesic effect as well as its role in trigeminal neuropathic pain require further investigation. This study investigated the ability of NGF to induce facial heat hyperalgesia and the involvement of tyrosine kinase receptor A, transient receptor potential vanilloid 1, and mast cells in NGF pronociceptive effects. In addition, the role of NGF in heat hyperalgesia in a model of trigeminal neuropathic pain was evaluated. NGF injection into the upper lip of naive rats induced long-lasting heat hyperalgesia. Pretreatment with an antibody anti-NGF, antagonists of tyrosine kinase receptor A, and transient receptor potential vanilloid 1 receptors or compound 48/80, to induce mast-cell degranulation, all attenuated NGF-induced hyperalgesia. In a rat model of trigeminal neuropathic pain, local treatment with anti-NGF significantly reduced heat hyperalgesia. In addition, increased NGF levels were detected in the ipsilateral infraorbital nerve branch at the time point that represents the peak of heat hyperalgesia. The results suggest that NGF is a prominent hyperalgesic mediator in the trigeminal system and it may represent a potential therapeutic target for the management of painful orofacial conditions, including trigeminal neuropathic pain.

Heat-induced accumulation and futile cycling of trehalose in Saccharomyces cerevisiae

International Nuclear Information System (INIS)

Hottiger, T.; Schmutz, P.; Wiemken, A.

1987-01-01

Heat shock resulted in rapid accumulation of large amounts of trehalose in Saccharomyces cerevisiae. In cultures growing exponentially on glucose, the trehalose content of the cells increased from 0.01 to 1 g/g of protein within 1 h after the incubation temperature was shifted from 27 to 40 0 C. When the temperature was readjusted to 27 0 C, the accumulated trehalose was rapidly degraded. In parallel, the activity of the trehalose-phosphate synthase, the key enzyme of trehalose biosynthesis, increased about six fold during the heat shock and declined to normal level after readjustment of the temperature. Surprisingly, the activity of neutral trehalase, the key enzyme of trehalose degradation, also increased about threefold during the heat shock and remained almost constant during recovery of the cells at 27 0 C. In pulse-labeling experiments with [ 14 C] glucose, trehalose was found to be turned over rapidly in heat-shocked cells, indicating that both anabolic and catabolic enzymes of trehalose metabolism were active in vivo. Possible functions of the heat-induced accumulation of trehalose and its rapid turnover in an apparently futile cycle during heat shock are discussed

Coherent phonon excitation and linear thermal expansion in structural dynamics and ultrafast electron diffraction of laser-heated metals.

Science.gov (United States)

Tang, Jau

2008-04-28

In this study, we examine the ultrafast structural dynamics of metals induced by a femtosecond laser-heating pulse as probed by time-resolved electron diffraction. Using the two-temperature model and the Grüneisen relationship we calculate the electron temperature, phonon temperature, and impulsive force at each atomic site in the slab. Together with the Fermi-Pasta-Ulam anharmonic chain model we calculate changes of bond distance and the peak shift of Bragg spots or Laue rings. A laser-heated thin slab is shown to exhibit "breathing" standing-wave behavior, with a period equal to the round-trip time for sound wave and a wavelength twice the slab thickness. The peak delay time first increases linearly with the thickness (linear thermal expansion due to lattice temperature jump are shown to contribute to the overall structural changes. Differences between these two mechanisms and their dependence on film thickness and other factors are discussed.

Development of micro-structured heat exchangers; Developpement d'echangeurs de chaleur microstructures

Energy Technology Data Exchange (ETDEWEB)

Bouzon, C.

2004-10-01

This study has been carried out to defend the Technological Diploma of Research, in the aim to develop micro-structured heat exchangers. Realized within the Research Group on the Heat exchangers and Energy (GREThE) of the Atomic Energy Commission (CEA) of Grenoble. The rise of micro-technologies and the optimization of heat exchangers have led to emergence from few years of new structures of fluid paths with scales lower than the millimeter, thus making it possible to produce heat exchangers ultra-compacts. The micro-structured exchangers are heat exchangers whose hydraulic diameters are lower than the millimeter but with external dimensions of several centimeters. The study is based on two patents filed by the CEA and the characterization of these two geometries. A first concept of cross flow type finds applications with Gas/Liquid heat exchanger. A second type, a countercurrent, is more adapted to Liquid/Liquid applications. An approach with simplified analytical models and by numerical simulation was employed for each concept. An experimental study on the Gas/Liquid concept was also carried out. (author)

Structural, mechanical and light yield characterisation of heat treated LYSO:Ce single crystals for medical imaging applications

CERN Document Server

Mengucci, P; Auffray, E; Barucca, G; Cecchi, C; Chipaux, R; Cousson, A; Davì, F; Di Vara, N; Rinaldi, D; Santecchia, E

2015-01-01

Five single crystals of cerium-doped lutetium yttrium oxyorthosilicate (LYSO:Ce) grown by the Czochralski method were submitted to structural characterisation by X-ray (XRD) and neutron (ND) diffraction, scanning (SEM) and transmission (TEM) electron microscopy and energy dispersive microanalysis (EDS). The Ultimate Tensile Strength (UTS), the Young Modulus (YM) and the Light Yield (LY) of the samples were also measured in order to correlate the mechanical and the optical behaviour of the crystals with the characteristics of their microstructure. Two of the samples analysed were also heat treated at 300 °C for 10 h to evidence possible variations induced by the temperature in the optical and mechanical response of the crystals. Results showed that the mean compositional variations evidenced by the structural analyses do not affect the mechanical and optical behaviour of the samples. On the contrary, the thermal treatment could induce the formation of coherent spherical particles (size 10 to 15 nm), not unifo...

Recent research on inherent molecular structure, physiochemical properties, and bio-functions of food and feed-type Avena sativa oats and processing-induced changes revealed with molecular microspectroscopic techniques

Energy Technology Data Exchange (ETDEWEB)

Prates, Luciana Louzada [Department of Animal and Poultry Science, College of Agriculture and Bioresources, University of Saskatchewan, Saskatoon, Saskatchewan, Canada; Yu, Peiqiang [Department of Animal and Poultry Science, College of Agriculture and Bioresources, University of Saskatchewan, Saskatoon, Saskatchewan, Canada

2017-05-16

Avena sativa oat is a cereal widely used as human food and livestock feed. However, the low metabolized energy and the rapid rumen degradations of protein and starch have limited the use of A. sativa oat grains. To overcome this disadvantage, new A. sativa oat varieties have been developed. Additionally, heat-related processing has been performed to decrease the degradation rate and improve the absorption of amino acids in the small intestine. The nutritive value is reflected by both chemical composition and inherent molecular structure conformation. However, the traditional wet chemical analysis is not able to detect the inherent molecular structures within an intact tissue. The advanced synchrotron-radiation and globar-based molecular microspectroscopy have been developed recently and applied to study internal molecular structures and the processing induced structure changes in A. sativa oats and reveal how molecular structure changes in relation to nutrient availability. This review aimed to obtain the recent information regarding physiochemical properties, molecular structures, metabolic characteristics of protein, and the heat-induced changes in new A. sativa oat varieties. The use of the advanced vibrational molecular spectroscopy was emphasized, synchrotron- and globar-based (micro)spectroscopy, to reveal the inherent structure of A. sativa oats at cellular and molecular levels and to reveal the heat processing effect on the degradation characteristics and the protein molecular structure in A. sativa oats. The relationship between nutrient availability and protein molecular inherent structure was also presented. Information described in this review gives better insight in the physiochemical properties, molecular structure, and the heat-induced changes in A. sativa oat detected with advanced molecular spectroscopic techniques in combinination with conventional nutrition study techniques.

ATF1 Modulates the Heat Shock Response by Regulating the Stress-Inducible Heat Shock Factor 1 Transcription Complex

Science.gov (United States)

Takii, Ryosuke; Fujimoto, Mitsuaki; Tan, Ke; Takaki, Eiichi; Hayashida, Naoki; Nakato, Ryuichiro; Shirahige, Katsuhiko

2014-01-01

The heat shock response is an evolutionally conserved adaptive response to high temperatures that controls proteostasis capacity and is regulated mainly by an ancient heat shock factor (HSF). However, the regulation of target genes by the stress-inducible HSF1 transcription complex has not yet been examined in detail in mammalian cells. In the present study, we demonstrated that HSF1 interacted with members of the ATF1/CREB family involved in metabolic homeostasis and recruited them on the HSP70 promoter in response to heat shock. The HSF1 transcription complex, including the chromatin-remodeling factor BRG1 and lysine acetyltransferases p300 and CREB-binding protein (CBP), was formed in a manner that was dependent on the phosphorylation of ATF1. ATF1-BRG1 promoted the establishment of an active chromatin state and HSP70 expression during heat shock, whereas ATF1-p300/CBP accelerated the shutdown of HSF1 DNA-binding activity during recovery from acute stress, possibly through the acetylation of HSF1. Furthermore, ATF1 markedly affected the resistance to heat shock. These results revealed the unanticipated complexity of the primitive heat shock response mechanism, which is connected to metabolic adaptation. PMID:25312646

Membrane fusion activity of vesicular stomatitis virus glycoprotein G is induced by low pH but not by heat or denaturant

International Nuclear Information System (INIS)

Yao Yi; Ghosh, Kakoli; Epand, Raquel F.; Epand, Richard M.; Ghosh, Hara P.

2003-01-01

The fusogenic envelope glycoprotein G of the rhabdovirus vesicular stomatitis virus (VSV) induces membrane fusion at acidic pH. At acidic pH the G protein undergoes a major structural reorganization leading to the fusogenic conformation. However, unlike other viral fusion proteins, the low-pH-induced conformational change of VSV G is completely reversible. As well, the presence of an α-helical coiled-coil motif required for fusion by a number of viral and cellular fusion proteins was not predicted in VSV G protein by using a number of algorithms. Results of pH dependence of the thermal stability of G protein as determined by intrinsic Trp fluorescence and circular dichroism (CD) spectroscopy show that the G protein is equally stable at neutral or acidic pH. Destabilization of G structure at neutral pH with either heat or urea did not induce membrane fusion or conformational change(s) leading to membrane fusion. Taken together, these data suggest that the mechanism of VSV G-induced fusion is distinct from the fusion mechanism of fusion proteins that involve a coiled-coil motif

Small-angle X-ray scattering studies of metastable intermediates of beta-lactoglobulin isolated after heat-induced aggregation

DEFF Research Database (Denmark)

Carrotta, R.; Arleth, L.; Pedersen, J.S.

2003-01-01

Small-angle x-ray scattering was used for studying intermediate species, isolated after heat-induced aggregation of the A variant of bovine P-lactoglobulin. The intermediates were separated in two fractions, the heated metastable dimer and heated metastable oligomers larger than the dimer. The pa...

Porous Foam Based Wick Structures for Loop Heat Pipes

Science.gov (United States)

Silk, Eric A.

2012-01-01

As part of an effort to identify cost efficient fabrication techniques for Loop Heat Pipe (LHP) construction, NASA Goddard Space Flight Center's Cryogenics and Fluids Branch collaborated with the U.S. Naval Academy s Aerospace Engineering Department in Spring 2012 to investigate the viability of carbon foam as a wick material within LHPs. The carbon foam was manufactured by ERG Aerospace and machined to geometric specifications at the U.S. Naval Academy s Materials, Mechanics and Structures Machine Shop. NASA GSFC s Fractal Loop Heat Pipe (developed under SBIR contract #NAS5-02112) was used as the validation LHP platform. In a horizontal orientation, the FLHP system demonstrated a heat flux of 75 Watts per square centimeter with deionized water as the working fluid. Also, no failed start-ups occurred during the 6 week performance testing period. The success of this study validated that foam can be used as a wick structure. Furthermore, given the COTS status of foam materials this study is one more step towards development of a low cost LHP.

Investigation of heat treatment conditions of structural material for blanket fabrication process

International Nuclear Information System (INIS)

Hirose, Takanori; Suzuki, Satoshi; Akiba, Masato; Shiba, Kiyoyuki; Sawai, Tomotsugu; Jitsukawa, Shiro

2004-01-01

This paper presents recent results of thermal hysteresis effects on ceramic breeder blanket structural material. Reduced activation ferritic/martensitic (RAF) steel is the leading candidates for the first wall structural materials of breeding blankets. RAF steel demonstrates superior resistance to high dose neutron irradiation, because the steel has tempered martensite structure which contains the number of sink site for radiation defects. This microstructure obtained by two-step heat treatment, first is normalizing at temperature above 1200 K and the second is tempering at temperature below 1100 K. Recent study revealed the thermal hysteresis has significant impacts on the post-irradiation mechanical properties. The breeding blanket has complicated structure, which consists of tungsten armor and thin first wall with cooling pipe. The blanket fabrication requires some high temperature joining processes. Especially hot isostatic pressing (HIP) is examined as a near-net-shape fabrication process for this structure. The process consists of heating above 1300 K and isostatic pressing at the pressure above 150 MPa followed by tempering. Moreover ceramics pebbles are packed into blanket module and the module is to be seamed by welding followed by post weld heat treatment in the final assemble process. Therefore the final microstructural features of RAFs strongly depend on the blanket fabrication process. The objective of this work is to evaluate the effects of thermal hysteresis corresponding to blanket fabrication process on RAFs microstructure in order to establish appropriate blanket fabrication process. Japanese RAFs F82H (Fe-0.1C-8Cr-2W-0.2V-0.05Ta) was investigated by metallurgical method after isochronal heat treatment up to 1473 K simulating high temperature bonding process. Although F82H showed significant grain growth after conventional solid HIP conditions (1313 K x 2 hr.), this coarse grained microstructure was refined by the post HIP normalizing at

Development of the heat sink structure of a beam dump for the proton accelerator

International Nuclear Information System (INIS)

Maeng, W. Y.; Gil, C. S.; Kim, J. H.; Kim, D. H.

2007-01-01

The beam dump is the essential component for the good beam quality and the reliable performance of the proton accelerator. The beam dump for a 20 MeV and 20 mA proton accelerator was designed and manufactured in this study. The high heats deposited, and the large amount of radioactivity produced in beam dump should be reduced by the proper heat sink structure. The heat source by the proton beam of 20 MeV and 20 mA was calculated. The radioactivity assessments of the beam dump were carried out for the economic shielding design with safety. The radioactivity by the protons and secondary neutrons in designed beam dump were calculated in this sturdy. The effective engineering design for the beam dump cooling was performed, considering the mitigation methods of the deposited heats with small angle, the power densities with the stopping ranges in the materials and the heat distributions in the beam dump. The heat sink structure of the beam dump was designed to meet the accelerator characteristics by placing two plates of 30 cm by 60 cm at an angle of 12 degree. The highest temperatures of the graphite, copper, and copper faced by cooling water were designed to be 223 degree, 146 degree, and 85 degree, respectively when the velocity of cooling water was 3 m/s. The heat sink structure was manufactured by the brazing graphite tiles to a copper plate with the filler alloy of Ti-Cu-Ag. The brazing procedure was developed. The tensile stress of the graphite was less than 75% of a maximum tensile stress during the accelerator operation based on the analysis. The safety analyses for the commissioning of the accelerator operation were also performed. The specimens from the brazed parts of beam dump structure were made to identify manufacturing problems. The soundness of the heat sink structure of the beam dump was confirmed by the fatigue tests of the brazed specimens of the graphite-copper tile components with the repetitive heating and cooling. The heat sink structure developed

Crystal Structure of the HEAT Domain from the Pre-mRNA Processing Factor Symplekin

Energy Technology Data Exchange (ETDEWEB)

Kennedy, Sarah A.; Frazier, Monica L.; Steiniger, Mindy; Mast, Ann M.; Marzluff, William F.; Redinbo, Matthew R.; (UNC)

2010-09-30

The majority of eukaryotic pre-mRNAs are processed by 3'-end cleavage and polyadenylation, although in metazoa the replication-dependent histone mRNAs are processed by 3'-end cleavage but not polyadenylation. The macromolecular complex responsible for processing both canonical and histone pre-mRNAs contains the {approx} 1160-residue protein Symplekin. Secondary-structural prediction algorithms identified putative HEAT domains in the 300 N-terminal residues of all Symplekins of known sequence. The structure and dynamics of this domain were investigated to begin elucidating the role Symplekin plays in mRNA maturation. The crystal structure of the Drosophila melanogaster Symplekin HEAT domain was determined to 2.4 {angstrom} resolution with single-wavelength anomalous dispersion phasing methods. The structure exhibits five canonical HEAT repeats along with an extended 31-amino-acid loop (loop 8) between the fourth and fifth repeat that is conserved within closely related Symplekin sequences. Molecular dynamics simulations of this domain show that the presence of loop 8 dampens correlated and anticorrelated motion in the HEAT domain, therefore providing a neutral surface for potential protein-protein interactions. HEAT domains are often employed for such macromolecular contacts. The Symplekin HEAT region not only structurally aligns with several established scaffolding proteins, but also has been reported to contact proteins essential for regulating 3'-end processing. Together, these data support the conclusion that the Symplekin HEAT domain serves as a scaffold for protein-protein interactions essential to the mRNA maturation process.

Heat-processed ginseng saponin ameliorates the adenine-induced renal failure in rats

OpenAIRE

Kim, Eun Jin; Oh, Hyun-A; Choi, Hyuck Jai; Park, Jeong Hill; Kim, Dong-Hyun; Kim, Nam Jae

2013-01-01

To evaluate the effect of the saponin of heat-processed ginseng (Sun ginseng, SG), we investigated the protective effect of SG total saponin fraction against adenine-induced chronic renal failure in rats. SG saponin significantly decreased the levels of urea nitrogen and creatinine in the serum, but increased the urinary excretion of urea nitrogen and creatinine, indicating an improvement of renal function. SG saponin also inhibited adenine-induced kidney hypertrophy and edema. SG saponin red...

A study on heat transfer through the fin-wick structure mounted in the evaporator for a plate loop heat pipe system

International Nuclear Information System (INIS)

Nguyen, Xuan Hung; Sung, Byung Ho; Choi, Jee Hoon; Kim, Chul Ju; Yoo, Jung Hyung; Seo, Min Whan

2008-01-01

This paper investigates the plate loop heat pipe system with an evaporator mounted with fin-wick structure to dissipate effectively the heat generated by the electronic components. The heat transfer formulation is modeled and predicted through thermal resistance analysis of the fin-wick structure in the evaporator. The experimental approach measures the thermal resistances and the operating characteristics. These results gathered in this investigation have been used to the objective of the information to improve the LHP system design so as to apply as the future cooling devices of the electronic components

Biologically Synthesized Gold Nanoparticles Ameliorate Cold and Heat Stress-Induced Oxidative Stress in Escherichia coli

Directory of Open Access Journals (Sweden)

Xi-Feng Zhang

2016-06-01

Full Text Available Due to their unique physical, chemical, and optical properties, gold nanoparticles (AuNPs have recently attracted much interest in the field of nanomedicine, especially in the areas of cancer diagnosis and photothermal therapy. Because of the enormous potential of these nanoparticles, various physical, chemical, and biological methods have been adopted for their synthesis. Synthetic antioxidants are dangerous to human health. Thus, the search for effective, nontoxic natural compounds with effective antioxidative properties is essential. Although AuNPs have been studied for use in various biological applications, exploration of AuNPs as antioxidants capable of inhibiting oxidative stress induced by heat and cold stress is still warranted. Therefore, one goal of our study was to produce biocompatible AuNPs using biological methods that are simple, nontoxic, biocompatible, and environmentally friendly. Next, we aimed to assess the antioxidative effect of AuNPs against oxidative stress induced by cold and heat in Escherichia coli, which is a suitable model for stress responses involving AuNPs. The response of aerobically grown E. coli cells to cold and heat stress was found to be similar to the oxidative stress response. Upon exposure to cold and heat stress, the viability and metabolic activity of E. coli was significantly reduced compared to the control. In addition, levels of reactive oxygen species (ROS and malondialdehyde (MDA and leakage of proteins and sugars were significantly elevated, and the levels of lactate dehydrogenase activity (LDH and adenosine triphosphate (ATP significantly lowered compared to in the control. Concomitantly, AuNPs ameliorated cold and heat-induced oxidative stress responses by increasing the expression of antioxidants, including glutathione (GSH, glutathione S-transferase (GST, super oxide dismutase (SOD, and catalase (CAT. These consistent physiology and biochemical data suggest that AuNPs can ameliorate cold and

Design and heat load analysis of support structure of CR superconducting dipole magnet for FAIR

International Nuclear Information System (INIS)

Zhu Yinfeng; Wu Songtao; Wu Weiyue; Xu Houchang; Liu Changle

2008-01-01

In order to meet the requirement of the Collector ring (CR) dipole superconducting magnet of FAIR in the process of operation, meanwhile, and to ensure the heat loads coming from the support structures to be lower than the design demands, the 3D models of support structures have been constructed with CATIA, then the calculation of low-temperature heat-load and the structure analysis have been done with ANSYS, the support structure material, 316LN+G10, is decided according to the heat-load calculation and the structure optimization, these results are necessary for manufacturing the formal magnet. (authors)

Heat, Acid and Chemically Induced Unfolding Pathways, Conformational Stability and Structure-Function Relationship in Wheat α-Amylase.

Directory of Open Access Journals (Sweden)

Kritika Singh

Full Text Available Wheat α-amylase, a multi-domain protein with immense industrial applications, belongs to α+β class of proteins with native molecular mass of 32 kDa. In the present study, the pathways leading to denaturation and the relevant unfolded states of this multi-domain, robust enzyme from wheat were discerned under the influence of temperature, pH and chemical denaturants. The structural and functional aspects along with thermodynamic parameters for α-amylase unfolding were probed and analyzed using fluorescence, circular dichroism and enzyme assay methods. The enzyme exhibited remarkable stability up to 70°C with tendency to aggregate at higher temperature. Acid induced unfolding was also incomplete with respect to the structural content of the enzyme. Strong ANS binding at pH 2.0 suggested the existence of a partially unfolded intermediate state. The enzyme was structurally and functionally stable in the pH range 4.0-9.0 with 88% recovery of hydrolytic activity. Careful examination of biophysical properties of intermediate states populated in urea and GdHCl induced denaturation suggests that α-amylase unfolding undergoes irreversible and non-coincidental cooperative transitions, as opposed to previous reports of two-state unfolding. Our investigation highlights several structural features of the enzyme in relation to its catalytic activity. Since, α-amylase has been comprehensively exploited for use in a range of starch-based industries, in addition to its physiological significance in plants and animals, knowledge regarding its stability and folding aspects will promote its biotechnological applications.

Pool boiling with high heat flux enabled by a porous artery structure

Science.gov (United States)

Bai, Lizhan; Zhang, Lianpei; Lin, Guiping; Peterson, G. P.

2016-06-01

A porous artery structure utilizing the concept of "phase separation and modulation" is proposed to enhance the critical heat flux of pool boiling. A series of experiments were conducted on a range of test articles in which multiple rectangular arteries were machined directly into the top surface of a 10.0 mm diameter copper rod. The arteries were then covered by a 2.0 mm thickness microporous copper plate through silver brazing. The pool wall was fabricated from transparent Pyrex glass to allow a visualization study, and water was used as the working fluid. Experimental results confirmed that the porous artery structure provided individual flow paths for the liquid supply and vapor venting, and avoided the detrimental effects of the liquid/vapor counter flow. As a result, a maximum heat flux of 610 W/cm2 over a heating area of 0.78 cm2 was achieved with no indication of dryout, prior to reaching the heater design temperature limit. Following the experimental tests, the mechanisms responsible for the boiling critical heat flux and performance enhancement of the porous artery structure were analyzed.

Structural analysis and evaluation of the 241SY101 tank annulus heat-up

International Nuclear Information System (INIS)

Ziada, H.H.

1994-01-01

This document provides the structural analysis (static and thermal loads) of the 241SY101 tank to determine the maximum allowable temperature and rate of heating that could be applied to tank 241SY101 through annulus air heating without detrimental effects to the structural integrity of the concrete and steel liner of the tank

Study of heat exchange in cooling systems of heat-stressed structures

Science.gov (United States)

Vikulin, A. V.; Yaroslavtsev, N. L.; Zemlyanaya, V. A.

2017-01-01

Increasing working parameters of the cycle of gas-turbine engines, complicating design of gas-turbine plants, as well as growing aerodynamic, thermal, static, and dynamic loads, necessitate the development of promising cooling systems for heat-stressed structures. This work is devoted to an experimental study of heat exchange in ducts equipped with systems of inclined and cross walls (fins). It has been found that an increase in the Reynolds number Re from 3000 to 20000 leads to a decrease in the heat exchange, which is characterized by the relative Nusselt number overline{Nu}, by 19-30% at the angle of inclination of the walls φ = 0, 40°, 50°, and 90° if the length of the walls x w is comparable to the spacing b s and by 12-15% at φ = 30° and 90° if x w ≫ b s. If cross walls are used in cooling ducts, the length of the walls x w plays the governing role; an increase in this characteristic from 1.22 × 10-3 to 3.14 × 10-3 m leads to an increase in the intensity of heat exchange by 30-40% and to a decrease in the capacity of the entire system of the walls. It has been shown that, on surfaces with wavy fins, the intensity of heat exchange is closest to that determined in the models under study. For example, values of the Colborne criterion StPr2/3 for ducts equipped with wavy fins and for the models under study differ only slightly (by 2-20% depending on the value of the angle φ). However, the difference for surfaces with short plate fins and ducts equipped with inclined walls is high (30-40%). This is due to the design features of these surfaces and to the severe effect of the inlet portion on heat exchange, since the surfaces are characterized by a higher ratio of the duct length to the hydraulic diameter L/d h at small fin thicknesses ((0.1-0.15) × 10-3 m). The experimental results can be used in developing designs of nozzle and rotor blades of high-temperature gas turbines in gas-turbine engines and plants.

Sensitization to heat by the polyamines and their analogs

Energy Technology Data Exchange (ETDEWEB)

Fuller, D.J.; Gerner, E.W.

1983-07-01

The polyamines putrescine, spermidine, and spermine have been shown to sensitize Chinese hamster ovary (CHO) cells to the cytotoxic effects of elevated temperatures. This sensitization occurs in the order spermine greater than spermidine greater than putrescine. A series of homologs of the diamine putrescine demonstrated little variance in the degree of potentiation until a chain length equivalent to that of spermidine was employed (1,8-diaminooctane). Two compounds bearing structural similarities to spermidine gave rather different results when combined with heat. Methylglyoxal bis(guanylhydrazone) (MGBG), an antiproliferative drug, sensitized cells to heat, while S-2-(3-aminopropylamino)-ethyl phosphoric acid (WR-2721), a radioprotector, had no measureable effect on 43 degrees C-induced cytotoxicity. Together, these results point out the primary importance of two terminal amino groups separated by either carbon, or carbon and nitrogen, atoms in an aliphatic chain in the observed sensitization of heat-induced cytotoxicity by polyamines. These data suggest specific dimensional characteristics of the presumed negatively charged structure(s) with which the polyamines are interacting to elicit this effect.

Heat priming induces trans-generational tolerance to high temperature stress in wheat

Directory of Open Access Journals (Sweden)

Xiao eWang

2016-04-01

Full Text Available Wheat plants are very sensitive to high temperature stress during grain filling. Effects of heat priming applied to the first generation on tolerance of the successive generation to post-anthesis high temperature stress were investigated. Compared with the progeny of non-heat primed plants (NH, the progeny of heat-primed plants (PH possessed higher grain yield, leaf photosynthesis and activities of antioxidant enzymes and lower cell membrane damage under high temperature stress. In the transcriptome profile, 1430 probes showed obvious difference in expression between PH and NH. These genes were related to signal transduction, transcription, energy, defense, and protein destination and storage, respectively. The gene encoding the lysine-specific histone demethylase 1 (LSD1 which was involved in histone demethylation related to epigenetic modification was up-regulated in the PH compared with NH. The proteome analysis indicated that the proteins involved in photosynthesis, energy production and protein destination and storage were up-regulated in the PH compared with NH. In short, thermos-tolerance was induced through heritable epigenetic alternation and signaling transduction, both processes further triggered prompt modifications of defense related responses in anti-oxidation, transcription, energy production, and protein destination and storage in the progeny of the primed plants under high temperature stress. It was concluded that trans-generation thermo-tolerance was induced by heat priming in the first generation, and this might be an effective measure to cope with severe high-temperature stresses during key growth stages in wheat production.

Activated platelets release sphingosine 1-phosphate and induce hypersensitivity to noxious heat stimuli in vivo

Directory of Open Access Journals (Sweden)

Daniela eWeth

2015-04-01

Full Text Available At the site of injury activated platelets release various mediators, one of which is sphingosine 1-phosphate (S1P. It was the aim of this study to explore whether activated human platelets had a pronociceptive effect in an in vivo mouse model and whether this effect was based on the release of S1P and subsequent activation of neuronal S1P receptors 1 or 3. Human platelets were prepared in different concentrations (105/µl, 106/µl, 107/µl and assessed in mice with different genetic backgrounds (WT, S1P1fl/fl, SNS-S1P1-/-, S1P3-/-. Intracutaneous injections of activated human platelets induced a significant, dose-dependent hypersensitivity to noxious thermal stimulation. The degree of heat hypersensitivity correlated with the platelet concentration as well as the platelet S1P content and the amount of S1P released upon platelet activation as measured with LC MS/MS. Despite the significant correlations between S1P and platelet count, no difference in paw withdrawal latency (PWL was observed in mice with a global null mutation of the S1P3 receptor or a conditional deletion of the S1P1 receptor in nociceptive primary afferents. Furthermore, neutralisation of S1P with a selective anti-S1P antibody did not abolish platelet induced heat hypersensitivity. Our results suggest that activated platelets release S1P and induce heat hypersensitivity in vivo. However, the platelet induced heat hypersensitivity was caused by mediators other than S1P.

Light induced cooling of a heated solid immersed in liquid helium I

International Nuclear Information System (INIS)

Lezak, D.; Brodie, L.C.; Semura, J.S.

1984-01-01

This chapter investigates the marked enhancement in the transient heat transfer from the heater-thermometer to the liquid helium immediately following the application of a flash of visible light. This ''light effect'' is associated with increased bubble activity, and it is possible that the light induces a rapid nucleation of bubbles in the superheated liquid at or near the heater surface. A summary of the light effect is presented and some potential uses to which this effect could be applied are suggested. Quantification of the light effect and properties of the light effect are discussed. It is determined that the light effect is an additional cooling due to a light induced enhancement of boiling in superheated liquid helium I. The effect could be applied in practical cryogenic engineering and for the acquisition of fundamental knowledge of boiling heat transfer and nucleation in cryogenic liquids

Characterization of six small HSP genes from Chironomus riparius (Diptera, Chironomidae): Differential expression under conditions of normal growth and heat-induced stress.

Science.gov (United States)

Martín-Folgar, Raquel; de la Fuente, Mercedes; Morcillo, Gloria; Martínez-Guitarte, José-Luis

2015-10-01

Small heat shock proteins (sHSPs) comprise the most numerous, structurally diverse, and functionally uncharacterized family of heat shock proteins. Several Hsp genes (Hsp 90, 70, 40, and 27) from the insect Chironomus riparius are widely used in aquatic toxicology as biomarkers for environmental toxins. Here, we conducted a comparative study and characterized secondary structure of the six newly identified sHsp genes Hsp17, Hsp21, Hsp22, Hsp23, Hsp24, and Hsp34. A characteristic α-crystallin domain is predicted in all the new proteins. Phylogenetic analysis suggests a strong relation to other sHSPs from insects and interesting evidence regarding evolutionary origin and duplication events. Comparative analysis of transcription profiles for Hsp27, Hsp70, and the six newly identified genes revealed that Hsp17, Hsp21, and Hsp22 are constitutively expressed under normal conditions, while under two different heat shock conditions these genes are either not activated or are even repressed (Hsp22). In contrast, Hsp23, Hsp24, and Hsp34 are significantly activated along with Hsp27 and Hsp70 during heat stress. These results strongly suggest functional differentiation within the small HSP subfamily and provide new data to help understand the coping mechanisms induced by stressful environmental stimuli. Copyright © 2015 Elsevier Inc. All rights reserved.

Circulating antibodies to inducible heat shock protein 70 in patients with uveitis

NARCIS (Netherlands)

de Smet, M. D.; Ramadan, A.

2001-01-01

Heat shock proteins with molecular weight 70 kDa (hsp70) are highly conserved immunogenic intracellular molecules. There are two main subtypes: one is expressed constitutively (hsc70), while the other is induced under stressful conditions (ihsp70). Using an ELISA directed against recombinant human

Expression of three sHSP genes involved in heat pretreatment-induced chilling tolerance in banana fruit.

Science.gov (United States)

He, Li-hong; Chen, Jian-ye; Kuang, Jian-fei; Lu, Wang-jin

2012-07-01

Banana fruit is highly susceptible to chilling injury. In previous research it was shown that heat pretreatment of banana fruit at 38 °C for 3 days before storage at a chilling temperature of 8 °C for 12 days prevented increases in visible chilling injury index, electrolyte leakage and malondialdehyde content and also decreases in lightness and chroma, indicating that heat pretreatment could effectively alleviate chilling injury of banana fruit. However, little is known about the role of small heat shock proteins (sHSPs) in postharvest chilling tolerance of banana fruit. In the present study, three cytosolic sHSP expression profiles in peel and pulp tissues of banana fruit during heat pretreatment and subsequent chilled storage (8 °C) were investigated in relation to heat pretreatment-induced chilling tolerance. Three full-length cDNAs of cytosolic sHSP genes, including two class I sHSP (CI sHSP) and one class II sHSP (CII sHSP) cDNAs, named Ma-CI sHSP1, Ma-CI sHSP2 and Ma-CII sHSP3 respectively, were isolated and characterised from harvested banana fruit. Accumulation of Ma-CI sHSP1 mRNA transcripts in peel and pulp tissues and Ma-CII sHSP3 mRNA transcripts in peel tissue increased during heat pretreatment. Expression of all three Ma-sHSP genes in peel and pulp tissues was induced during subsequent chilled storage. Furthermore, Ma-CI sHSP1 and Ma-CII sHSP3 mRNA transcripts in pulp tissue and Ma-CI sHSP2 mRNA transcripts in peel and pulp tissues were obviously enhanced by heat pretreatment at days 6 and 9 of subsequent chilled storage. These results suggested that heat pretreatment enhanced the expression of Ma-sHSPs, which might be involved in heat pretreatment-induced chilling tolerance of banana fruit. Copyright © 2012 Society of Chemical Industry.

Determination of Heating Value of Estonian Oil Shale by Laser-Induced Breakdown Spectroscopy

Directory of Open Access Journals (Sweden)

M. Aints

2018-01-01

Full Text Available The laser-induced breakdown spectroscopy (LIBS combined with multivariate regression analysis of measured data were utilised for determination of the heating value and the chemical composition of pellets made from Estonian oil shale samples with different heating values. The study is the first where the oil shale heating value is determined on the basis of LIBS spectra. The method for selecting the optimal number of spectral lines for ordinary multivariate least squares regression model is presented. The correlation coefficient between the heating value predicted by the regression model, and that measured by calorimetric bomb, was R2=0.98. The standard deviation of prediction was 0.24 MJ/kg. Concentrations of oil shale components predicted by the regression model were compared with those measured by ordinary methods.

Fluid induced structural vibrations in steam generators and heat exchangers

International Nuclear Information System (INIS)

Catton, I.; Adinolfi, P.; Alquaddoomi, O.

2003-01-01

Fluid-elastic instability (FEI) in tube bundle heat exchangers was studied experimentally. The motion of an array of 15 stainless steel vibrating tubes (Φ 25.4mm) in water cross-flow, suspended using stainless steel piano wire has been recorded with a CCD camera. The individual motion and relative motion of the tubes are reported and can be used for computational model validation. The relative displacement of the tubes allows identification of the most potentially damaging patterns of tube bundle vibration. A critical reduced velocity may be determined by specification of an allowable limit on tube motion amplitude. Measurements were made for various tube array configurations, tube natural frequencies and flow conditions. (author)

Insights into the Molecular Events That Regulate Heat-Induced Chilling Tolerance in Citrus Fruits.

Science.gov (United States)

Lafuente, María T; Establés-Ortíz, Beatriz; González-Candelas, Luis

2017-01-01

Low non-freezing temperature may cause chilling injury (CI), which is responsible for external quality deterioration in many chilling-sensitive horticultural crops. Exposure of chilling-sensitive citrus cultivars to non-lethal high-temperature conditioning may increase their chilling tolerance. Very little information is available about the molecular events involved in such tolerance. In this work, the molecular events associated with the low temperature tolerance induced by heating Fortune mandarin, which is very sensitive to chilling, for 3 days at 37°C prior to cold storage is presented. A transcriptomic analysis reveals that heat-conditioning has an important impact favoring the repression of genes in cold-stored fruit, and that long-term heat-induced chilling tolerance is an active process that requires activation of transcription factors involved in transcription initiation and of the WRKY family. The analysis also shows that chilling favors degradation processes, which affect lipids and proteins, and that the protective effect of the heat-conditioning treatment is more likely to be related to the repression of the genes involved in lipid degradation than to the modification of fatty acids unsaturation, which affects membrane permeability. Another major factor associated with the beneficial effect of the heat treatment on reducing CI is the regulation of stress-related proteins. Many of the genes that encoded such proteins are involved in secondary metabolism and in oxidative stress-related processes.

Insights into the Molecular Events That Regulate Heat-Induced Chilling Tolerance in Citrus Fruits

Directory of Open Access Journals (Sweden)

María T. Lafuente

2017-06-01

Full Text Available Low non-freezing temperature may cause chilling injury (CI, which is responsible for external quality deterioration in many chilling-sensitive horticultural crops. Exposure of chilling-sensitive citrus cultivars to non-lethal high-temperature conditioning may increase their chilling tolerance. Very little information is available about the molecular events involved in such tolerance. In this work, the molecular events associated with the low temperature tolerance induced by heating Fortune mandarin, which is very sensitive to chilling, for 3 days at 37°C prior to cold storage is presented. A transcriptomic analysis reveals that heat-conditioning has an important impact favoring the repression of genes in cold-stored fruit, and that long-term heat-induced chilling tolerance is an active process that requires activation of transcription factors involved in transcription initiation and of the WRKY family. The analysis also shows that chilling favors degradation processes, which affect lipids and proteins, and that the protective effect of the heat-conditioning treatment is more likely to be related to the repression of the genes involved in lipid degradation than to the modification of fatty acids unsaturation, which affects membrane permeability. Another major factor associated with the beneficial effect of the heat treatment on reducing CI is the regulation of stress-related proteins. Many of the genes that encoded such proteins are involved in secondary metabolism and in oxidative stress-related processes.

The kinetics of removal of heat-induced excess nuclear protein

International Nuclear Information System (INIS)

Roti, J.L.R.; Uygur, N.; Higashikubo, R.

1984-01-01

To investigate the role of protein content, temperature and heating time in the removal of heat-induced excess protein associated with the isolated nucleus, the kinetics of protein removal was monitored for 6 to 8 hours following exposure to 7 hyperthermic protocols. Four of these (47 0 C-7.5 min., 46 0 C-15 min., 45 0 C-30 min., and 44 0 C-60 min.) resulted in a nuclear protein content approximately twice that of nuclei from unheated cells (2.05 +- .14) following heat exposure. Three protocols (45 0 C-15 min., 44 0 C-30 min. and 43 0 C-60 min.) resulted in a nuclear protein content approximately 1.6 times normal (1.63 +- .12). If nuclear protein content were the only determinant in the recovery rate, then the same half time for nuclear protein removal would be expected within each group of protocols. Rate constants for nuclear protein removal were obtained by regression analysis. The half-time for nuclear protein removal increased with decreasing temperature and increasing heating time for the same nuclear protein content. This result suggests that the heating time and temperature are more of a determinant in the removal kinetics than protein content alone. Extended kinetics of recovery (to 36 hours) showed incomplete recovery and a secondary increase in protein associated with the isolated nucleus. These results were due to cell-cycle rearrangement (G/sub 2/ block) and unbalanced growth

INTERACTION OF LASER RADIATION WITH MATTER: Calculation of the kinetics of heating and structural changes in the cartilaginous tissue under the action of laser radiation

Science.gov (United States)

Sobol', E. N.; Kitai, M. S.

1998-07-01

A theoretical model is developed for the calculation of the temperature fields and determination of the size of a zone with structural changes in the cartilaginous tissue. The model is based on a simultaneous analysis of the heat and mass transfer processes and it takes into account the bulk absorption of laser radiation by the tissue, surface evaporation of water, and temperature dependences of the diffusion coefficients. It is assumed that under the influence of a phase transition between free and bound water, caused by heating of the cartilage to 70°C, the proteoglycans of the cartilage matrix become mobile and, as a result of such mass transfer, structural changes are induced in the cartilaginous tissue causing relaxation of stresses or denaturation. It is shown that the maximum temperature is then reached not on the irradiated surface but at some distance from it, and that the size of the zones of structural changes (denaturation depth) depends strongly on the energy density of the laser radiation and its wavelength, on the duration of the irradiation, and on the cartilage thickness. This model makes it possible to calculate the temperature fields and the depth of structural changes in laser-induced relaxation of stresses and changes in the shape of the cartilaginous tissue.

Alfvén Wave Turbulence as a Coronal Heating Mechanism: Simultaneously Predicting the Heating Rate and the Wave-induced Emission Line Broadening

Energy Technology Data Exchange (ETDEWEB)

Oran, R. [Department of Earth, Atmospheric, and Planetary Sciences, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139 (United States); Landi, E.; Holst, B. van der; Sokolov, I. V.; Gombosi, T. I., E-mail: roran@mit.edu [Atmospheric, Oceanic and Atmospheric Sciences, University of Michigan, 2455 Hayward, Ann Arbor, MI, 48109 (United States)

2017-08-20

We test the predictions of the Alfvén Wave Solar Model (AWSoM), a global wave-driven magnetohydrodynamic (MHD) model of the solar atmosphere, against high-resolution spectra emitted by the quiescent off-disk solar corona. AWSoM incorporates Alfvén wave propagation and dissipation in both closed and open magnetic field lines; turbulent dissipation is the only heating mechanism. We examine whether this mechanism is consistent with observations of coronal EUV emission by combining model results with the CHIANTI atomic database to create synthetic line-of-sight spectra, where spectral line widths depend on thermal and wave-related ion motions. This is the first time wave-induced line broadening is calculated from a global model with a realistic magnetic field. We used high-resolution SUMER observations above the solar west limb between 1.04 and 1.34 R {sub ⊙} at the equator, taken in 1996 November. We obtained an AWSoM steady-state solution for the corresponding period using a synoptic magnetogram. The 3D solution revealed a pseudo-streamer structure transversing the SUMER line of sight, which contributes significantly to the emission; the modeled electron temperature and density in the pseudo-streamer are consistent with those observed. The synthetic line widths and the total line fluxes are consistent with the observations for five different ions. Further, line widths that include the contribution from the wave-induced ion motions improve the correspondence with observed spectra for all ions. We conclude that the turbulent dissipation assumed in the AWSoM model is a viable candidate for explaining coronal heating, as it is consistent with several independent measured quantities.

Controlling Heat Transport and Flow Structures in Thermal Turbulence Using Ratchet Surfaces

Science.gov (United States)

Jiang, Hechuan; Zhu, Xiaojue; Mathai, Varghese; Verzicco, Roberto; Lohse, Detlef; Sun, Chao

2018-01-01

In this combined experimental and numerical study on thermally driven turbulence in a rectangular cell, the global heat transport and the coherent flow structures are controlled with an asymmetric ratchetlike roughness on the top and bottom plates. We show that, by means of symmetry breaking due to the presence of the ratchet structures on the conducting plates, the orientation of the large scale circulation roll (LSCR) can be locked to a preferred direction even when the cell is perfectly leveled out. By introducing a small tilt to the system, we show that the LSCR orientation can be tuned and controlled. The two different orientations of LSCR give two quite different heat transport efficiencies, indicating that heat transport is sensitive to the LSCR direction over the asymmetric roughness structure. Through a quantitative analysis of the dynamics of thermal plume emissions and the orientation of the LSCR over the asymmetric structure, we provide a physical explanation for these findings. The current work has important implications for passive and active flow control in engineering, biofluid dynamics, and geophysical flows.

Structures to radiate heat softly

Energy Technology Data Exchange (ETDEWEB)

Perilae, T.; Wikstroem, T. [ed.

1997-11-01

Over the past fifty years, heating systems in single-family houses have taken a great leap forward. First wood-burning stoves gave way to oil heaters; then these were superseded by central heating systems; and now conventional central heating systems have lost their way with the increasingly widespread use of room-specific heating systems

Rapid insight into heating-induced phase transformations in the solid state of the calcium salt of atorvastatin using multivariate data analysis

DEFF Research Database (Denmark)

Christensen, Niels Peter Aae; Van Eerdenbrugh, Bernard; Kwok, Kaho

2013-01-01

To investigate the heating-induced dehydration and melting behavior of the trihydrate phase of the calcium salt of atorvastatin.......To investigate the heating-induced dehydration and melting behavior of the trihydrate phase of the calcium salt of atorvastatin....

Effects of rare sugar d-allulose on heat-induced gelation of surimi prepared from marine fish.

Science.gov (United States)

Ogawa, Masahiro; Inoue, Masaki; Hayakawa, Shigeru; O'Charoen, Siwaporn; Ogawa, Makiko

2017-11-01

d-Allulose (Alu), the C3-epimer of d-fructose, is a non-caloric sweetener (0.39 kcal g -1 ) with a suppressive effect on postprandial blood glucose elevation. The aim of this study was to investigate the effects of Alu used as a sweetener and gel improver instead of sucrose on heat-induced gelation of surimi. The puncture test of a heat-induced surimi gel showed that with 50 g kg -1 Alu the gel had 15% and 6% higher gel strength than the corresponding gel with sucrose (Suc) and with sorbitol (Sor), respectively. In addition, Alu-gel had 26% and 25% higher water-holding capacity (WHC) than Suc- and Sor-gel. Heating of myofibrillar protein with Alu, unlike Suc and Sor, facilitated the formation of both disulfide and non-disulfide crosslinks that might be associated with the mechanical properties and WHC of Alu-gel. Alu improves the mechanical properties and WHC of the heat-induced surimi gel. Furthermore, Alu is low in calories compared with Suc (4.0 kcal g -1 ) and Sor (3.0 kcal g -1 ). Thus Alu will be an alternative of Suc or Sor for developing surimi-based products with health benefits. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

Structural changes in connective tissues caused by a moderate laser heating

International Nuclear Information System (INIS)

Bagratashvili, Viktor N; Bagratashvili, N V; Sviridov, A P; Shakh, G Sh; Ignat'eva, Natalia Yu; Lunin, Valery V; Grokhovskaya, T E; Averkiev, S V

2002-01-01

The structural changes in adipose and fibrous tissues caused by 2- and 3-W IR laser irradiation are studied by the methods of IR and Raman spectroscopy and differential scanning calorimetry. It is shown that heating of fibrous tissue samples to 50 0 C and adipose tissue samples to 75 0 C by IR laser radiation changes the supramolecular structure of their proteins and triacylglycerides, respectively, without the intramolecular bond breaking. Heating of fibrous tissue to 70 0 C and adipose tissue to 90 - 110 0 C leads to a partial reversible denaturation of proteins and to oxidation of fats.

Heat- and radiation-induced radio- and thermo-tolerance of Zea mays seedlings

International Nuclear Information System (INIS)

Gikoshvili, T.I.; Vagabova, M.Eh.; Vilenchik, M.M.; Kuzin, A.M.

1985-01-01

It was shown that γ-irradiation of Zea mays seedlings with low doses (1-3 Gy) induced thermotolerance, and preheating up to 43 deg C increased their radioresistance and thermotolerance. A hypothesis of the formation of common protective proteins after exposure to low - level radiation and heat is discussed

SAXS observation of structural evolution of heated olefin

International Nuclear Information System (INIS)

Sun Minhua; Mou Hongchen; Wang Yuxi; Li Demin; Wang Aiping; Ma Congxiao; Cheng Weidong; Wang Dan; Liu Jia

2007-01-01

Structural evolution of olefin during its heating process was observed with SAXS method at Beijing Synchrotron Radiation Facility. The mean square fluctuation of electron density increased from 468.5 nm -2 at 22 degree C to 2416 nm -2 at 100 degree C, while the electronic gyration radius decreased from 11.61 nm at 22 degree C to 11.16 nm at 100 degree C. Therefore, the olefin softens as a result of the increased thermal motion of the molecules, rather than the shrinking size of fundamental structural units of olefin. (authors)

PECULIARITIES OF FORMATION OF CORPORATE STRUCTURES IN THE HEAT SUPPLY SYSTEM OF THE REGION

Directory of Open Access Journals (Sweden)

Oleg A. Donichev

2013-01-01

Full Text Available The article contains the research results of formation and functioning of corporate structures of the regional heat power engineering. A geometrical model of interactions between hierarchy levels of this structure is proposed. The role of the government in an improvement of the effectiveness of the heat supply system of regions is proved.

Heat-shock-induced enhanced reactivation of UV-irradiated Herpesvirus

Energy Technology Data Exchange (ETDEWEB)

Yager, J.D.; Zurlo, J.; Penn, A.L.

1985-09-01

The objective of this study was to compare the ability of heat shock (HS) with that of another type of cellular stress, UV irradiation, to cause the induction of enhanced viral reactivation, a process that may represent an SOS-type repair process in mammalian cells. These results indicate that, like UV irradiation, HS at levels inhibitory to cell growth induced enhanced viral reactivation in Vero cells. The results also suggest that at least two proteins in the HS protein family are not necessary for this response to occur. (Auth.). 27 refs.; 5 figs.

Jupiter Thermospheric General Circulation Model (JTGCM): Global Structure and Dynamics Driven by Auroral and Joule Heating

Science.gov (United States)

Bougher, S. W.; J. Il. Waite, Jr.; Majeed, T.

2005-01-01

A growing multispectral database plus recent Galileo descent measurements are being used to construct a self-consistent picture of the Jupiter thermosphere/ionosphere system. The proper characterization of Jupiter s upper atmosphere, embedded ionosphere, and auroral features requires the examination of underlying processes, including the feedbacks of energetics, neutral-ion dynamics, composition, and magnetospheric coupling. A fully 3-D Jupiter Thermospheric General Circulation Model (JTGCM) has been developed and exercised to address global temperatures, three-component neutral winds, and neutral-ion species distributions. The domain of this JTGCM extends from 20-microbar (capturing hydrocarbon cooling) to 1.0 x 10(exp -4) nbar (including aurora/Joule heating processes). The resulting JTGCM has been fully spun-up and integrated for greater than or equal to40 Jupiter rotations. Results from three JTGCM cases incorporating moderate auroral heating, ion drag, and moderate to strong Joule heating processes are presented. The neutral horizontal winds at ionospheric heights vary from 0.5 km/s to 1.2 km/s, atomic hydrogen is transported equatorward, and auroral exospheric temperatures range from approx.1200-1300 K to above 3000 K, depending on the magnitude of Joule heating. The equatorial temperature profiles from the JTGCM are compared with the measured temperature structure from the Galileo AS1 data set. The best fit to the Galileo data implies that the major energy source for maintaining the equatorial temperatures is due to dynamical heating induced by the low-latitude convergence of the high-latitude-driven thermospheric circulation. Overall, the Jupiter thermosphere/ionosphere system is highly variable and is shown to be strongly dependent on magnetospheric coupling which regulates Joule heating.

Heat flow, heat generation and crustal thermal structure of the northern block of the South Indian Craton

Science.gov (United States)

Gupta, Mohan L.; Sharma, S. R.; Sundar, A.

Heat flow values and heat generation data calculated from the concentration of heat producing radioactive elements, U, Th and K in surface rocks were analyzed. The South Indian Craton according to Drury et al., can be divided into various blocks, separated by late Proterozoic shear belts. The northern block comprises Eastern and Western Dharwar Cratons of Rogers (1986), Naqvi and Rogers (1987) and a part of the South Indian granulite terrain up to a shear system occupying the Palghat-Cauvery low lands. The geothermal data analysis clearly demonstrates that the present thermal characteristics of the above two Archaean terrains of the Indian and Australian Shields are quite similar. Their crustal thermal structures are likely to be similar also.

Heat flow, heat generation and crustal thermal structure of the northern block of the South Indian Craton

Science.gov (United States)

Gupta, Mohan L.; Sharma, S. R.; Sundar, A.

1988-01-01

Heat flow values and heat generation data calculated from the concentration of heat producing radioactive elements, U, Th and K in surface rocks were analyzed. The South Indian Craton according to Drury et al., can be divided into various blocks, separated by late Proterozoic shear belts. The northern block comprises Eastern and Western Dharwar Cratons of Rogers (1986), Naqvi and Rogers (1987) and a part of the South Indian granulite terrain up to a shear system occupying the Palghat-Cauvery low lands. The geothermal data analysis clearly demonstrates that the present thermal characteristics of the above two Archaean terrains of the Indian and Australian Shields are quite similar. Their crustal thermal structures are likely to be similar also.

Renoprotective effect of virgin coconut oil in heated palm oil diet-induced hypertensive rats.

Science.gov (United States)

Kamisah, Yusof; Ang, Shu-Min; Othman, Faizah; Nurul-Iman, Badlishah Sham; Qodriyah, Hj Mohd Saad

2016-10-01

Virgin coconut oil, rich in antioxidants, was shown to attenuate hypertension. This study aimed to investigate the effects of virgin coconut oil on blood pressure and related parameters in kidneys in rats fed with 5-times-heated palm oil (5HPO). Thirty-two male Sprague-Dawley rats were divided into 4 groups. Two groups were fed 5HPO (15%) diet and the second group was also given virgin coconut oil (1.42 mL/kg, oral) daily for 16 weeks. The other 2 groups were given basal diet without (control) and with virgin coconut oil. Systolic blood pressure was measured pre- and post-treatment. After 16 weeks, the rats were sacrificed and kidneys were harvested. Dietary 5HPO increased blood pressure, renal thiobarbituric acid reactive substance (TBARS), and nitric oxide contents, but decreased heme oxygenase activity. Virgin coconut oil prevented increase in 5HPO-induced blood pressure and renal nitric oxide content as well as the decrease in renal heme oxygenase activity. The virgin coconut oil also reduced the elevation of renal TBARS induced by the heated oil. However, neither dietary 5HPO nor virgin coconut oil affected renal histomorphometry. In conclusion, virgin coconut oil has a potential to reduce the development of hypertension and renal injury induced by dietary heated oil, possibly via its antioxidant protective effects on the kidneys.

Resveratrol induces antioxidant and heat shock protein mRNA expression in response to heat stress in black-boned chickens.

Science.gov (United States)

Liu, L L; He, J H; Xie, H B; Yang, Y S; Li, J C; Zou, Y

2014-01-01

This study investigated the effects of dietary resveratrol at 0, 200, 400, or 600 mg/kg of diet on the performance, immune organ growth index, serum parameters, and expression levels of heat shock protein (Hsp) 27, Hsp70, and Hsp90 mRNA in the bursa of Fabricius, thymus, and spleen of 42-d-old female black-boned chickens exposed to heat stress at 37 ± 2°C for 15 d. The results showed that heat stress reduced daily feed intake and BW gain; decreased serum glutathione (GSH), growth hormone, and insulin-like growth factor-1 levels; and inhibited GSH peroxidase (GSH-Px), superoxide dismutase (SOD), and catalase (CAT) activities compared with birds subjected to thermo-neutral circumstances. Chickens that were fed diets supplemented with resveratrol exhibited a linear increase in feed intake and BW gain (P stress. In contrast, serum malonaldehyde concentrations were decreased (P stress also reduced (P stress and coincided with an increase in supplemental resveratrol levels. The expression of Hsp27, Hsp70, and Hsp90 mRNA in the bursa of Fabricius and spleen were increased (P stress compared with no heat stress. Resveratrol attenuated the heat stress-induced overexpression of Hsp27, Hsp70, and Hsp90 mRNA in the bursa of Fabricius and spleen and increased the low expression of Hsp27 and Hsp90 mRNA in thymus upon heat stress. The results suggest that supplemental resveratrol improves growth performance and reduces oxidative stress in heat-stressed black-boned chickens by increasing serum growth hormone concentrations and modulating the expression of heat shock genes in organs of the immune system.

Cellular stress induces cancer stem-like cells through expression of DNAJB8 by activation of heat shock factor 1.

Science.gov (United States)

Kusumoto, Hiroki; Hirohashi, Yoshihiko; Nishizawa, Satoshi; Yamashita, Masamichi; Yasuda, Kazuyo; Murai, Aiko; Takaya, Akari; Mori, Takashi; Kubo, Terufumi; Nakatsugawa, Munehide; Kanaseki, Takayuki; Tsukahara, Tomohide; Kondo, Toru; Sato, Noriyuki; Hara, Isao; Torigoe, Toshihiko

2018-03-01

In a previous study, we found that DNAJB8, a heat shock protein (HSP) 40 family member is expressed in kidney cancer stem-like cells (CSC)/cancer-initiating cells (CIC) and that it has a role in the maintenance of kidney CSC/CIC. Heat shock factor (HSF) 1 is a key transcription factor for responses to stress including heat shock, and it induces HSP family expression through activation by phosphorylation. In the present study, we therefore examined whether heat shock (HS) induces CSC/CIC. We treated the human kidney cancer cell line ACHN with HS, and found that HS increased side population (SP) cells. Western blot analysis and qRT-PCR showed that HS increased the expression of DNAJB8 and SOX2. Gene knockdown experiments using siRNAs showed that the increase in SOX2 expression and SP cell ratio depends on DNAJB8 and that the increase in DNAJB8 and SOX2 depend on HSF1. Furthermore, treatment with a mammalian target of rapamycin (mTOR) inhibitor, temsirolimus, decreased the expression of DNAJB8 and SOX2 and the ratio of SP cells. Taken together, the results indicate that heat shock induces DNAJB8 by activation of HSF1 and induces cancer stem-like cells. © 2018 The Authors. Cancer Science published by John Wiley & Sons Australia, Ltd on behalf of Japanese Cancer Association.

Controlling heat transport and flow structures in thermal turbulence using ratchet surfaces

Science.gov (United States)

Sun, Chao; Jiang, Hechuan; Zhu, Xiaojue; Mathai, Varghese; Verzicco, Roberto; Lohse, Detlef

2017-11-01

In this combined experimental and numerical study on thermally driven turbulence in a rectangular cell, the global heat transport and the coherent flow structures are controlled with an asymmetric ratchet-like roughness on the top and bottom plates. We show that, by means of symmetry breaking due to the presence of the ratchet structures on the conducting plates, the orientation of the Large Scale Circulation Roll (LSCR) can be locked to a preferred direction even when the cell is perfectly leveled out. By introducing a small tilt to the system, we show that the LSCR orientation can be tuned and controlled. The two different orientations of LSCR give two quite different heat transport efficiencies, indicating that heat transport is sensitive to the LSCR direction over the asymmetric roughness structure. Through analysis of the dynamics of thermal plume emissions and the orientation of the LSCR over the asymmetric structure, we provide a physical explanation for these findings. This work is financially supported by the Natural Science Foundation of China under Grant No. 11672156, the Dutch Foundation for Fundamental Research on Matter (FOM), the Dutch Technology Foundation (STW) and a VIDI Grant.

Geldanamycin induces heat shock protein 70 and protects against MPTP-induced dopaminergic neurotoxicity in mice.

Science.gov (United States)

Shen, Hai-Ying; He, Jin-Cai; Wang, Yumei; Huang, Qing-Yuan; Chen, Jiang-Fan

2005-12-02

As key molecular chaperone proteins, heat shock proteins (HSPs) represent an important cellular protective mechanism against neuronal cell death in various models of neurological disorders. In this study, we investigated the effect as well as the molecular mechanism of geldanamycin (GA), an inhibitor of Hsp90, on 1-methyl-4-pheny-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity, a mouse model of Parkinson disease. Neurochemical analysis showed that pretreatment with GA (via intracerebral ventricular injection 24 h prior to MPTP treatment) increased residual dopamine content and tyrosine hydroxylase immunoreactivity in the striatum 24 h after MPTP treatment. To dissect out the molecular mechanism underlying this neuroprotection, we showed that the GA-mediated protection against MPTP was associated with a reduction of cytosolic Hsp90 and an increase in Hsp70, with no significant changes in Hsp40 and Hsp25 levels. Furthermore, in parallel with the induction of Hsp70, striatal nuclear HSF1 levels and HSF1 binding to heat shock element sites in the Hsp70 promoter were significantly enhanced by the GA pretreatment. Together these results suggested that the molecular cascade leading to the induction of Hsp70 is critical to the neuroprotection afforded by GA against MPTP-induced neurotoxicity in the brain and that pharmacological inhibition of Hsp90 may represent a potential therapeutic strategy for Parkinson disease.

Robust heat-inducible gene expression by two endogenous hsp70-derived promoters in transgenic Aedes aegypti

Science.gov (United States)

Carpenetti, Tiffany L. G.; Aryan, Azadeh; Myles, Kevin M.; Adelman, Zach N.

2011-01-01

Aedes aegypti is an important vector of the viruses that cause dengue fever, dengue hemorrhagic fever, and yellow fever. Reverse genetic approaches to the study of gene function in this mosquito have been limited by the lack of a robust inducible promoter to allow precise temporal control over a protein-encoding or hairpin RNA transgene. Likewise, investigations into the molecular and biochemical basis of vector competence would benefit from the ability to activate an anti-pathogen molecule at specific times during infection. We have characterized the ability of genomic sequences derived from two Ae. aegypti hsp70 genes to drive heat-inducible expression of a reporter in both transient and germline transformation contexts. AaHsp70-luciferase transcripts accumulated specifically after heat shock, and displayed a pattern of rapid induction and decay similar to endogenous AaHsp70 genes. Luciferase expression in transgenic Ae. aegypti increased by ∼25-50 fold in whole adults by four hours after heat-shock, with significant activity (∼20 fold) remaining at 24 hr. Heat-induced expression was even more dramatic in midgut tissues, with one strain showing a ∼2500-fold increase in luciferase activity. The AaHsp70 promoters described could be valuable for gene function studies as well as for the precise timing of the expression of anti-pathogen molecules. PMID:22142225

Solar-simulated radiation and heat treatment induced metalloproteinase-1 expression in cultured dermal fibroblasts via distinct pathways: implications on reduction of sun-associated aging.

Science.gov (United States)

Lan, Cheng-Che E; Wu, Ching-Shang; Yu, Hsin-Su

2013-12-01

Sun exposure is an important environmental factor affecting human beings. Most knowledge regarding solar aging focused on light radiation (photoaging), and little emphasis has been placed on heat, a factor that is also closely associated with sun exposure. This study was launched to evaluate the effects of simulated solar radiation (SSR) and environmental heat on skin fibroblasts in terms of dermal aging. Cultured human dermal fibroblasts were treated with moderate amount of SSR (200J/cm(2)) and heat (+2°C). The metalloproteinase-1 (MMP-1) expression was used as a surrogate marker for dermal aging and the involved regulatory mechanisms were explored. Both treatment conditions did not affect viability but significantly increased the expressions of MMP-1. In parallel, both treatments increased the intracellular levels of reactive oxygen species (ROS), but the increase induced by SSR is much greater than heat. In contrast, transient receptor potential vanilloid 1 (TRPV-1), the sensor of environmental heat, was upregulated by heat but not SSR treatment. Pretreating fibroblasts with antioxidant abrogated the SSR-induced MMP-1 but has limited effect on heat-induced MMP-1. On the other hand, TRPV-1 antagonist pretreatment reduced heat-induced MMP-1 in fibroblasts but not their SSR-treated counterparts. Both SSR and heat induced MMP-1 expression in dermal fibroblasts but through different pathways. As current strategies for reducing sun-related aging focused on filtering of light and use of antioxidants, future strategies design to reduce solar aging should also incorporate heat-induced aging into consideration. Copyright © 2013 Japanese Society for Investigative Dermatology. Published by Elsevier Ireland Ltd. All rights reserved.

Relationship between the shear viscosity and heating rate in metallic glasses below the glass transition

International Nuclear Information System (INIS)

Khonik, Vitaly A.; Kobelev, N. P.

2008-01-01

It has been shown that first-order irreversible structural relaxation with distributed activation energies must lead to a linear decrease of the logarithm of Newtonian shear viscosity with the logarithm of heating rate upon linear heating of glass. Such a behavior is indeed observed in the experiments on metallic glasses. Structural relaxation-induced viscous flow leads to infra-low-frequency Maxwell viscoelastic internal friction, which is predicted to increase with the heating rate

Critical heat flux on micro-structured zircaloy surfaces for flow boiling of water at low pressures

International Nuclear Information System (INIS)

Haas, C.; Miassoedov, A.; Schulenberg, T.; Wetzel, T.

2012-01-01

The influence of surface structure on critical heat flux for flow boiling of water was investigated for Zircaloy tubes in a vertical annular test section. The objectives were to find suitable surface modification processes for Zircaloy tubes and to test their critical heat flux performance in comparison to the smooth tube. Surface structures with micro-channels, porous layer, oxidized layer, and elevations in micro- and nano-scale were produced on a section of a Zircaloy cladding tube. These modified tubes were tested in an internally heated vertical annulus with a heated length of 326 mm and an inner and outer diameter of 9.5 and 18 mm. The experiments were performed with mass fluxes of 250 and 400 kg/(m 2 s), outlet pressures between 120 and 300 kPa, and constant inlet subcooling enthalpy of 167 kJ/kg. Only a small influence of modified surface structures on critical heat flux was observed for the pressure of 120 kPa in the present test section geometry. However, with increasing pressure the critical heat flux could increase up to 29% using the surface structured tubes with micro-channels, porous and oxidized layers. Capillary effects and increased nucleation site density are assumed to improve the critical heat flux performance. (authors)

Involvement of DNA-PK and ATM in radiation- and heat-induced DNA damage recognition and apoptotic cell death

International Nuclear Information System (INIS)

Tomita, Masanori

2010-01-01

Exposure to ionizing radiation and hyperthermia results in important biological consequences, e.g. cell death, chromosomal aberrations, mutations, and DNA strand breaks. There is good evidence that the nucleus, specifically cellular DNA, is the principal target for radiation-induced cell lethality. DNA double-strand breaks (DSBs) are considered to be the most serious type of DNA damage induced by ionizing radiation. On the other hand, verifiable mechanisms which can lead to heat-induced cell death are damage to the plasma membrane and/or inactivation of heat-labile proteins caused by protein denaturation and subsequent aggregation. Recently, several reports have suggested that DSBs can be induced after hyperthermia because heat-induced phosphorylated histone H2AX (γ-H2AX) foci formation can be observed in several mammalian cell lines. In mammalian cells, DSBs are repaired primarily through two distinct and complementary mechanisms: non-homologous end joining (NHEJ), and homologous recombination (HR) or homology-directed repair (HDR). DNA-dependent protein kinase (DNA-PK) and ataxia-telangiectasia mutated (ATM) are key players in the initiation of DSB repair and phosphorylate and/or activate many substrates, including themselves. These phosphorylated substrates have important roles in the functioning of cell cycle checkpoints and in cell death, as well as in DSB repair. Apoptotic cell death is a crucial cell suicide mechanism during development and in the defense of homeostasis. If DSBs are unrepaired or misrepaired, apoptosis is a very important system which can protect an organism against carcinogenesis. This paper reviews recently obtained results and current topics concerning the role of DNA-PK and ATM in heat- or radiation-induced apoptotic cell death. (author)

Ordering effects on structure and specific heat of nonstoichiometric titanium carbide

International Nuclear Information System (INIS)

Lipatnikov, V.N.; Gusev, A.I.

1999-01-01

The experimental results on the change in the crystal structure and specific heat of the nonstoichiometric titanium carbide TiC y (0.5 2 C phases with cubic and trigonal symmetry and the rhombic ordered Ti 3 C 2 phase are formed in the titanium carbide at the temperature below 1000 K by the phase transitions mechanism. The temperatures and heats of the order-disorder phase transitions are determined [ru

Effects of molecular structure on microscopic heat transport in chain polymer liquids

International Nuclear Information System (INIS)

Matsubara, Hiroki; Kikugawa, Gota; Ohara, Taku; Bessho, Takeshi; Yamashita, Seiji

2015-01-01

In this paper, we discuss the molecular mechanism of the heat conduction in a liquid, based on nonequilibrium molecular dynamics simulations of a systematic series of linear- and branched alkane liquids, as a continuation of our previous study on linear alkane [T. Ohara et al., J. Chem. Phys. 135, 034507 (2011)]. The thermal conductivities for these alkanes in a saturated liquid state at the same reduced temperature (0.7T c ) obtained from the simulations are compared in relation to the structural difference of the liquids. In order to connect the thermal energy transport characteristics with molecular structures, we introduce the new concept of the interatomic path of heat transfer (atomistic heat path, AHP), which is defined for each type of inter- and intramolecular interaction. It is found that the efficiency of intermolecular AHP is sensitive to the structure of the first neighbor shell, whereas that of intramolecular AHP is similar for different alkane species. The dependence of thermal conductivity on different lengths of the main and side chain can be understood from the natures of these inter- and intramolecular AHPs

Effects of molecular structure on microscopic heat transport in chain polymer liquids

Energy Technology Data Exchange (ETDEWEB)

Matsubara, Hiroki, E-mail: matsubara@microheat.ifs.tohoku.ac.jp; Kikugawa, Gota; Ohara, Taku [Institute of Fluid Science, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai 980-8577 (Japan); Bessho, Takeshi; Yamashita, Seiji [Higashifuji Technical Center, Toyota Motor Corporation, 1200 Mishuku, Susono, Shizuoka 410-1193 (Japan)

2015-04-28

In this paper, we discuss the molecular mechanism of the heat conduction in a liquid, based on nonequilibrium molecular dynamics simulations of a systematic series of linear- and branched alkane liquids, as a continuation of our previous study on linear alkane [T. Ohara et al., J. Chem. Phys. 135, 034507 (2011)]. The thermal conductivities for these alkanes in a saturated liquid state at the same reduced temperature (0.7T{sub c}) obtained from the simulations are compared in relation to the structural difference of the liquids. In order to connect the thermal energy transport characteristics with molecular structures, we introduce the new concept of the interatomic path of heat transfer (atomistic heat path, AHP), which is defined for each type of inter- and intramolecular interaction. It is found that the efficiency of intermolecular AHP is sensitive to the structure of the first neighbor shell, whereas that of intramolecular AHP is similar for different alkane species. The dependence of thermal conductivity on different lengths of the main and side chain can be understood from the natures of these inter- and intramolecular AHPs.

Axial flow heat exchanger devices and methods for heat transfer using axial flow devices

Science.gov (United States)

Koplow, Jeffrey P.

2016-02-16

Systems and methods described herein are directed to rotary heat exchangers configured to transfer heat to a heat transfer medium flowing in substantially axial direction within the heat exchangers. Exemplary heat exchangers include a heat conducting structure which is configured to be in thermal contact with a thermal load or a thermal sink, and a heat transfer structure rotatably coupled to the heat conducting structure to form a gap region between the heat conducting structure and the heat transfer structure, the heat transfer structure being configured to rotate during operation of the device. In example devices heat may be transferred across the gap region from a heated axial flow of the heat transfer medium to a cool stationary heat conducting structure, or from a heated stationary conducting structure to a cool axial flow of the heat transfer medium.

Heating of the intracluster medium

International Nuclear Information System (INIS)

Just, A.; Deiss, B.M.; Kegel, W.H.; Boehringer, H.; Morfill, G.E.

1990-01-01

The gravitational interaction of the system of galaxies and the ICM are treated by fluctuation theory. Fluctuation theory seems to be more adequate to describe the gravitational interaction than local theories used up to now, because gravitation is a long-range force. Therefore, the dynamical friction and energy transfer depends mainly on the global structure of the gravitational wakes induced by the galaxies in the ICM. The ICM is described hydrodynamically by a nonpolytropic gas. The heating rate is derived as a local quantity on scales characteristic for cluster properties in quasi-linear approximation. The parameter dependence is given explicitly. The Coma cluster is taken as an example to show that mechanical heating by fluctuations may be essential for the structure of the cluster halos and cooling flows. 19 refs

Simulation of Structural Transformations in Heating of Alloy Steel

Science.gov (United States)

Kurkin, A. S.; Makarov, E. L.; Kurkin, A. B.; Rubtsov, D. E.; Rubtsov, M. E.

2017-07-01

Amathematical model for computer simulation of structural transformations in an alloy steel under the conditions of the thermal cycle of multipass welding is presented. The austenitic transformation under the heating and the processes of decomposition of bainite and martensite under repeated heating are considered. Amethod for determining the necessary temperature-time parameters of the model from the chemical composition of the steel is described. Published data are processed and the results used to derive regression models of the temperature ranges and parameters of transformation kinetics of alloy steels. The method developed is used in computer simulation of the process of multipass welding of pipes by the finite-element method.

Theory and design of heat exchanger : shell and tube condenser and reboiler

International Nuclear Information System (INIS)

Min, Ui Dong

1996-02-01

This book gives descriptions of shell and tube heat exchanger including from, sorts, structure like shell and shell side, channel, and sliding bar, basic design of heat exchanger, flow-induced vibration, shell side condenser, tube side condenser and design of basic structure of condenser by types, selection of reboiler type, kettle type reboiler, internal reboiler, pump through reboiler, design of reboiler like kettle and internal reboiler, and horizontal and vertical thermosyphon reboiler.

Prostaglandin E synthase interacts with inducible heat shock protein 70 after heat stress in bovine primary dermal fibroblast cells.

Science.gov (United States)

Richter, Constanze; Viergutz, Torsten; Schwerin, Manfred; Weitzel, Joachim M

2015-01-01

Exposure to heat stress in dairy cows leads to undesired side effects that are reflected by complex alterations in endocrine parameters, such as reduced progesterone, estradiol, and thyroid hormone concentrations. These endocrine maladaptation leads to failure to resume cyclicity, a poor uterine environment and inappropriate immune responses in postpartum dairy cows. Prostaglandins (PG's) are lipid mediators, which serve as signal molecules in response to various external stimuli as well as to cell-specific internal signal molecules. A central role in PG synthesis plays prostaglandin E synthase (PGES) that catalyzes the isomerization of PGH2 to PGE2 .The present study was conducted to investigate heat stress associated PGES expression. Expression of PGES and inducible heat shock protein 70 (HSP70), as a putative chaperonic protein, was studied in bovine primary fibroblasts under different heat shock conditions. Bovine primary fibroblasts produce PGE2 at homoiothermical norm temperature (38.5°C in bovine), but reduce PGE2 production rates under extreme heat stress (at 45°C for 6 h). By contrast, PGE2 production rates are maintained after a milder heat stress (at 41.5°C for 6 h). PGE2 synthesis is abolished by application of cyclooxygenase inhibitor indomethacin, indicating de novo synthesis. Heat stress increases HSP70 but not PGES protein concentrations. HSP70 physically interacts with PGES and the PGES-HSP70 complex did not dissociate upon heat stress at 45°C even after returning the cells to 37°C. The PGE2 production negatively correlates with the portion of PGES-HSP70 complex. These results suggest a protein interaction between HSP70 and PGES in dermal fibroblast cells. Blockage of PGES protein by HSP70 seems to interfere with the regulatory processes essential for cellular adaptive protection. © 2014 International Society for Advancement of Cytometry. © 2014 International Society for Advancement of Cytometry.

Direct measurements of sample heating by a laser-induced air plasma in pre-ablation spark dual-pulse laser-induced breakdown spectroscopy (LIBS).

Science.gov (United States)

Register, Janna; Scaffidi, Jonathan; Angel, S Michael

2012-08-01

Direct measurements of temperature changes were made using small thermocouples (TC), placed near a laser-induced air plasma. Temperature changes up to ~500 °C were observed. From the measured temperature changes, estimates were made of the amount of heat absorbed per unit area. This allowed calculations to be made of the surface temperature, as a function of time, of a sample heated by the air plasma that is generated during orthogonal pre-ablation spark dual-pulse (DP) LIBS measurements. In separate experiments, single-pulse (SP) LIBS emission and sample ablation rate measurements were performed on nickel at sample temperatures ranging from room temperature to the maximum surface temperature that was calculated using the TC measurement results (500 °C). A small, but real sample temperature-dependent increase in both SP LIBS emission and the rate of sample ablation was found for nickel samples heated up to 500 °C. Comparison of DP LIBS emission enhancement values for bulk nickel samples at room temperature versus the enhanced SP LIBS emission and sample ablation rates observed as a function of increasing sample temperature suggests that sample heating by the laser-induced air plasma plays only a minor role in DP LIBS emission enhancement.

Heat transfer and structure stress analysis of micro packaging component of high power light emitting diode

Directory of Open Access Journals (Sweden)

Hsu Chih-Neng

2013-01-01

Full Text Available This paper focuses on the heat transfer and structural stress analysis of the micro- scale packaging structure of a high-power light emitting diode. The thermal-effect and thermal-stress of light emitting diode are determined numerically. Light emitting diode is attached to the silicon substrate through the wire bonding process by using epoxy as die bond material. The silicon substrate is etched with holes at the bottom and filled with high conductivity copper material. The chip temperature and structure stress increase with input power consumption. The micro light emitting diode is mounted on the heat sink to increase the heat dissipation performance, to decrease chip temperature, to enhance the material structure reliability and safety, and to avoid structure failure as well. This paper has successfully used the finite element method to the micro-scale light emitting diode heat transfer and stress concentration at the edges through etched holes.

Ultraviolet light induced refractive index structures in germanosilica

DEFF Research Database (Denmark)

Svalgaard, Mikael

1997-01-01

The focus of the research presented in this ph.d. thesis is refractive index structures photoinduced in germanonsilica waveguides with ultra-violet (UV) radiation. The physical mechanisms involved in photosensitivity and applications of a wide range of UV induced refractive index structures in both...... application of a scanning near-field optical microscope to obtain high resolution images of UV induced refractive index structures and by monitoring the dynamics of UV induced index changes and luminescence. During part of my ph.d. project I have worked at the National Institute of Standards and Technolgy...

UV-induced structural changes in chromatin

International Nuclear Information System (INIS)

Lang, H.; Zimmer, C.; Vengerov, Yu.Yu.

1985-01-01

UV-induced structural alterations of chromatin were studied by means of CD, electron microscopic, and gel electrophoretic measurements. The results indicate that chromatin undergoes serious structural changes after irradiation even at very low fluences. In the low fluence range the structural transitions from the higher ordered chromatin structure to the unfolded state occur without detectable changes in the content of histone H1 and of the core histones. Histone H1 disappears only at fluences above 10 kJ/m 2 . Furthermore, DNA in chromatin is much more sensitive against UV-irradiation and shows a higher degree of strand scission relative to free DNA. While fragmentation in free DNA occurs at fluences above 15 kJ/m 2 , it occurs even at 5.5 kJ/m 2 in the case of chromatin. The biological meaning of the observed UV-induced structural alterations of chromatin is discussed. (author)

Heat-induced symmetry breaking in ant (Hymenoptera: Formicidae escape behavior.

Directory of Open Access Journals (Sweden)

Yuan-Kai Chung

Full Text Available The collective egress of social insects is important in dangerous situations such as natural disasters or enemy attacks. Some studies have described the phenomenon of symmetry breaking in ants, with two exits induced by a repellent. However, whether symmetry breaking occurs under high temperature conditions, which are a common abiotic stress, remains unknown. In our study, we deposited a group of Polyrhachis dives ants on a heated platform and counted the number of escaping ants with two identical exits. We discovered that ants asymmetrically escaped through two exits when the temperature of the heated platform was >32.75°C. The degree of asymmetry increased linearly with the temperature of the platform. Furthermore, the higher the temperature of heated platform was, the more ants escaped from the heated platform. However, the number of escaping ants decreased for 3 min when the temperature was higher than the critical thermal limit (39.46°C, which is the threshold for ants to endure high temperature without a loss of performance. Moreover, the ants tended to form small groups to escape from the thermal stress. A preparatory formation of ant grouping was observed before they reached the exit, indicating that the ants actively clustered rather than accidentally gathered at the exits to escape. We suggest that a combination of individual and grouping ants may help to optimize the likelihood of survival during evacuation.

RF Pulsed Heating

Energy Technology Data Exchange (ETDEWEB)

Pritzkau, David P.

2002-01-03

RF pulsed heating is a process by which a metal is heated from magnetic fields on its surface due to high-power pulsed RF. When the thermal stresses induced are larger than the elastic limit, microcracks and surface roughening will occur due to cyclic fatigue. Pulsed heating limits the maximum magnetic field on the surface and through it the maximum achievable accelerating gradient in a normal conducting accelerator structure. An experiment using circularly cylindrical cavities operating in the TE{sub 011} mode at a resonant frequency of 11.424 GHz is designed to study pulsed heating on OFE copper, a material commonly used in normal conducting accelerator structures. The high-power pulsed RF is supplied by an X-band klystron capable of outputting 50 MW, 1.5 {micro}s pulses. The test pieces of the cavity are designed to be removable to allow testing of different materials with different surface preparations. A diagnostic tool is developed to measure the temperature rise in the cavity utilizing the dynamic Q change of the resonant mode due to heating. The diagnostic consists of simultaneously exciting a TE{sub 012} mode to steady-state in the cavity at 18 GHz and measuring the change in reflected power as the cavity is heated from high-power pulsed RF. Two experimental runs were completed. One run was executed at a calculated temperature rise of 120 K for 56 x 10{sup 6} pulses. The second run was executed at a calculated temperature rise of 82 K for 86 x 10{sup 6} pulses. Scanning electron microscope pictures show extensive damage occurring in the region of maximum temperature rise on the surface of the test pieces.

Effect of a Traditional Herbal Prescription, Kyung-Ok-Ko, on Male Mouse Spermatogenic Ability after Heat-Induced Damage

Directory of Open Access Journals (Sweden)

Deok-Sang Hwang

2015-01-01

Full Text Available Kyung-Ok-Ko (KOK, a well-known traditional Korean medicinal formula, has long been used to invigorate the essential qi. This use of KOK may be associated with reproductive ability as a more modern concept. The protective effect of KOK was evaluated against deterioration of testicular function induced by heat exposure in male mice. Male fertility was disrupted by scrotal heat stress at 43°C for 5 weeks. KOK (0.25, 0.50, and 2.00 g/kg/day was administered orally at 3 h after the stress. To evaluate the protective effect of KOK, body weight, testicular weight, sperm count, sperm motility, and histopathological changes in the testes were evaluated. KOK-treated mice significantly recovered their general health, as evidenced by body weight. KOK-treated mice also showed significantly higher testes weights, sperm counts, and sperm motility than did the heat stress group. KOK-treated mice significantly recovered the morphological appearance of the seminiferous tubules and seminiferous epithelium. Furthermore, KOK-treated mice significantly increased antioxidant enzyme activities and reduced the protein expressions of apoptosis in the testes. KOK significantly protects against heat-induced damage to testicular function in male mice by inhibiting oxidative stress and apoptosis, indicating that KOK may be an effective agent for treatment of heat-induced male infertility.

Detect the sensitivity and response of protein molecular structure of whole canola seed (yellow and brown) to different heat processing methods and relation to protein utilization and availability using ATR-FT/IR molecular spectroscopy with chemometrics.

Science.gov (United States)

Samadi; Theodoridou, Katerina; Yu, Peiqiang

2013-03-15

The objectives of this experiment were to detect the sensitivity and response of protein molecular structure of whole canola seed to different heat processing [moisture (autoclaving) vs. dry (roasting) heating] and quantify heat-induced protein molecular structure changes in relation to protein utilization and availability. In this study, whole canola seeds were autoclaved (moisture heating) and dry (roasting) heated at 120 °C for 1h, respectively. The parameters assessed included changes in (1) chemical composition profile, (2) CNCPS protein subfractions (PA, PB1, PB2, PB3, PC), (3) intestinal absorbed true protein supply, (4) energy values, and (5) protein molecular structures (amide I, amide II, ratio of amide I to II, α-helix, β-sheet, ratio of α-helix to β-sheet). The results showed that autoclave heating significantly decreased (Pseed. Future study is needed to study response and impact of heat processing to each inherent layer of canola seed from outside to inside tissues and between yellow canola and brown canola. Copyright © 2012 Elsevier B.V. All rights reserved.

The Structural Heat Intercept-Insulation-Vibration Evaluation Rig (SHIVER)

Science.gov (United States)

Johnson, W. L.; Zoeckler, J. G.; Best-Ameen, L. M.

2015-01-01

NASA is currently investigating methods to reduce the boil-off rate on large cryogenic upper stages. Two such methods to reduce the total heat load on existing upper stages are vapor cooling of the cryogenic tank support structure and integration of thick multilayer insulation systems to the upper stage of a launch vehicle. Previous efforts have flown a 2-layer MLI blanket and shown an improved thermal performance, and other efforts have ground-tested blankets up to 70 layers thick on tanks with diameters between 2 3 meters. However, thick multilayer insulation installation and testing in both thermal and structural modes has not been completed on a large scale tank. Similarly, multiple vapor cooled shields are common place on science payload helium dewars; however, minimal effort has gone into intercepting heat on large structural surfaces associated with rocket stages. A majority of the vapor cooling effort focuses on metallic cylinders called skirts, which are the most common structural components for launch vehicles. In order to provide test data for comparison with analytical models, a representative test tank is currently being designed to include skirt structural systems with integral vapor cooling. The tank is 4 m in diameter and 6.8 m tall to contain 5000 kg of liquid hydrogen. A multilayer insulation system will be designed to insulate the tank and structure while being installed in a representative manner that can be extended to tanks up to 10 meters in diameter. In order to prove that the insulation system and vapor cooling attachment methods are structurally sound, acoustic testing will also be performed on the system. The test tank with insulation and vapor cooled shield installed will be tested thermally in the B2 test facility at NASAs Plumbrook Station both before and after being vibration tested at Plumbrooks Space Power Facility.

Psychosocial Stress-Induced Analgesia: An Examination of Effects on Heat Pain Threshold and Tolerance and of Neuroendocrine Mediation.

Science.gov (United States)

Gaab, Jens; Jiménez, Julia; Voneschen, Livia; Oschwald, Daniel; Meyer, Andrea H; Nater, Urs M; Krummenacher, Peter

2016-01-01

Stress-induced analgesia (SIA) is an adaptive response of reduced nociception following demanding acute internal and external stressors. Although a psychobiological understanding of this phenomenon is of importance for stress-related psychiatric and pain conditions, comparably little is known about the psychobiological mechanisms of SIA in humans. The aim of this study was to investigate the effects of acute psychosocial stress on heat pain perception and its possible neuroendocrine mediation by salivary cortisol levels and α-amylase activity in healthy men. Employing an intra-individual assessment of heat pain parameters, acute psychosocial stress did not influence heat pain threshold but significantly, albeit slightly, increased heat pain tolerance. Using linear mixed-model analysis, this effect of psychosocial stress on heat pain tolerance was not mediated by increases of salivary cortisol and state anxiety levels or by the activity of α-amylase. These results show that while psychosocial stress is selectively analgesic for heat pain tolerance, this observed effect is not mediated by stress-induced increases of salivary cortisol and α-amylase activity, as proxies of both the hypothalamus-pituitary-adrenal axis and the autonomic nervous system activation. © 2017 S. Karger AG, Basel.

Improvement of the CFC structure to withstand high heat flux

International Nuclear Information System (INIS)

Pestchanyi, S.; Landman, I.

2006-01-01

Analysis of the peculiarities of the erosion of NB31 CFC allowed proposition of a new CFC fibre structure for considerable reduction of the erosion rate. The improvement concerns the needling and vowing fibres arrangement only and keeping the same structure of the pitch fibres - the main heat conducting component of NB31. The needling and the vowing fibres of the improved structure provide the armour stiffness, comparable to that of NB31. Numerical simulation of erosion for CFC with the improved structure has confirmed that the erosion rate is four to five times lower in comparison with that of NB31

Laser cutting sandwich structure glass-silicon-glass wafer with laser induced thermal-crack propagation

Science.gov (United States)

Cai, Yecheng; Wang, Maolu; Zhang, Hongzhi; Yang, Lijun; Fu, Xihong; Wang, Yang

2017-08-01

Silicon-glass devices are widely used in IC industry, MEMS and solar energy system because of their reliability and simplicity of the manufacturing process. With the trend toward the wafer level chip scale package (WLCSP) technology, the suitable dicing method of silicon-glass bonded structure wafer has become necessary. In this paper, a combined experimental and computational approach is undertaken to investigate the feasibility of cutting the sandwich structure glass-silicon-glass (SGS) wafer with laser induced thermal-crack propagation (LITP) method. A 1064 nm semiconductor laser cutting system with double laser beams which could simultaneously irradiate on the top and bottom of the sandwich structure wafer has been designed. A mathematical model for describing the physical process of the interaction between laser and SGS wafer, which consists of two surface heating sources and two volumetric heating sources, has been established. The temperature stress distribution are simulated by using finite element method (FEM) analysis software ABAQUS. The crack propagation process is analyzed by using the J-integral method. In the FEM model, a stationary planar crack is embedded in the wafer and the J-integral values around the crack front edge are determined using the FEM. A verification experiment under typical parameters is conducted and the crack propagation profile on the fracture surface is examined by the optical microscope and explained from the stress distribution and J-integral value.

A DOUBLE KNOCKOUT; A NOVEL APPROACH TO UNDERSTANDING STRESS-INDUCIBLE 70 KDA HEAT SHOCK PROTEINS (HSP70S) ON DEVELOPMENT AND REPRODUCTION

Science.gov (United States)

Heat and chemical toxicants which disrupt spermatogenesis and cause male infertility are thought to induce the expression of Hsp70-1 and 70-3, the major inducible heat shock proteins of the 70kDa family. Previous studies from several laboratories including our own have characteri...

Nanocrystallinity induced by heating

DEFF Research Database (Denmark)

Mørup, Steen; Meaz, T.M.; Bender Koch, C.

1997-01-01

Samples of akaganeite (beta-FeOOH) and goethite (alpha-FeOOH) have been studied after heating at various temperatures up to 800 C. X-ray diffraction and Mossbauer spectroscopy measurements showed that slightly below the temperatures at which the samples transform to hematite (alpha-Fe2O3) the oxy......Samples of akaganeite (beta-FeOOH) and goethite (alpha-FeOOH) have been studied after heating at various temperatures up to 800 C. X-ray diffraction and Mossbauer spectroscopy measurements showed that slightly below the temperatures at which the samples transform to hematite (alpha-Fe2O3...

Protein structural development of threadfin bream ( Nemipterus spp.) surimi gels induced by glucose oxidase.

Science.gov (United States)

Wang, Lei; Fan, Daming; Fu, Lulu; Jiao, Xidong; Huang, Jianlian; Zhao, Jianxin; Yan, Bowen; Zhou, Wenguo; Zhang, Wenhai; Ye, Weijian; Zhang, Hao

2018-01-01

This study investigated the effect of glucose oxidase on the gel properties of threadfin bream surimi. The gel strength of surimi increased with the addition of 0.5‰ glucose oxidase after two-step heating. Based on the results of the chemical interactions, the hydrophobic interaction and disulfide bond of glucose oxidase-treated surimi samples increased compared with the control samples at the gelation temperature and gel modori temperature. The surface hydrophobicity of samples with glucose oxidase and glucose increased significantly ( p glucose oxidase induced more α-helixes to turn into a more elongated random and flocculent structure. Glucose oxidase changes the secondary structure of the surimi protein, making more proteins depolarize and stretch and causing actomyosin to accumulate to each other, resulting in the formation of surimi gel.

Effects of heat on meat proteins - Implications on structure and quality of meat products.

Science.gov (United States)

Tornberg, E

2005-07-01

Globular and fibrous proteins are compared with regard to structural behaviour on heating, where the former expands and the latter contracts. The meat protein composition and structure is briefly described. The behaviour of the different meat proteins on heating is discussed. Most of the sarcoplasmic proteins aggregate between 40 and 60 °C, but for some of them the coagulation can extend up to 90°C. For myofibrillar proteins in solution unfolding starts at 30-32°C, followed by protein-protein association at 36-40°C and subsequent gelation at 45-50°C (conc.>0.5% by weight). At temperatures between 53 and 63°C the collagen denaturation occurs, followed by collagen fibre shrinkage. If the collagen fibres are not stabilised by heat-resistant intermolecular bonds, it dissolves and forms gelatine on further heating. The structural changes on cooking in whole meat and comminuted meat products, and the alterations in water-holding and texture of the meat product that it leads to, are then discussed.

Identification of a cytotoxic molecule in heat-modified citrus pectin.

Science.gov (United States)

Leclere, Lionel; Fransolet, Maude; Cambier, Pierre; El Bkassiny, Sandy; Tikad, Abdellatif; Dieu, Marc; Vincent, Stéphane P; Van Cutsem, Pierre; Michiels, Carine

2016-02-10

Modified forms of citrus pectin possess anticancer properties. However, their mechanism of action and the structural features involved remain unclear. Here, we showed that citrus pectin modified by heat treatment displayed cytotoxic effects in cancer cells. A fractionation approach was used aiming to identify active molecules. Dialysis and ethanol precipitation followed by HPLC analysis evidenced that most of the activity was related to molecules with molecular weight corresponding to low degree of polymerization oligogalacturonic acid. Heat-treatment of galacturonic acid also generated cytotoxic molecules. Furthermore, heat-modified galacturonic acid and heat-fragmented pectin contained the same molecule that induced cell death when isolated by HPLC separation. Mass spectrometry analyses revealed that 4,5-dihydroxy-2-cyclopenten-1-one was one cytotoxic molecule present in heat-treated pectin. Finally, we synthesized the enantiopure (4R,5R)-4,5-dihydroxy-2-cyclopenten-1-one and demonstrated that this molecule was cytotoxic and induced a similar pattern of apoptotic-like features than heat-modified pectin. Copyright © 2015 Elsevier Ltd. All rights reserved.

[Heat shock protein 90--modulator of TNFalpha-induced apoptosis of Jurkat tumor cells].

Science.gov (United States)

Kaĭgorodova, E V; Riazantseva, N V; Novitskiĭ, V V; Moroshkina, A N; Belkina, M V; Iakushina, V D

2011-01-01

rTNFalpha-induced programmed death of Jurkat tumor cells cultured with 17-AAG, a selective inhibitor of heat shock protein (Hsp90), was studied by fluorescent microscopy with the use of FITC-labeled annexin V and propidium iodide. Caspase-3 and -8 activities were determined by spectrophotometry using a caspase- 3 and -8 colorimetric assay kit. It was shown that inhibition of Hsp90 leads to activation of Jurkat cell apoptosis while Hsp90 itself suppresses this process. 17-AAG enhances rTNFa-induced apoptosis of tumor cells.

Disruption of sugarcane bagasse lignocellulosic structure by means of dilute sulfuric acid pretreatment with microwave-assisted heating

International Nuclear Information System (INIS)

Chen, Wei-Hsin; Tu, Yi-Jian; Sheen, Herng-Kuang

2011-01-01

Highlights: → Pretreatment of dilute sulfuric acid on bagasse using microwave heating. → An increase in reaction temperature destroyed bagasse significantly. → Pretreated bagasse particles were characterized by fragmentation and swelling. → When the temperature was 190 o C, the fragmentation of particles became pronounced. → The influence of heating time on bagasse structure was not significant. - Abstract: Disruption of lignocellulosic structure of biomass plays a key role in producing bioethanol from lignocelluloses. This study investigated the impact of dilute sulfuric acid pretreatment on bagasse structure using microwave heating. Three reaction temperatures of 130, 160 and 190 o C with two heating times of 5 and 10 min were considered and a number of instruments were employed to analyze the properties of the bagasse particles. On account of microwave irradiation into the solution with dielectric heating, the experiments indicated that an increase in reaction temperature destroyed the lignocellulosic structure of bagasse in a significant way. The pretreated bagasse particles were simultaneously characterized by fragmentation and swelling. When the reaction temperature was as high as 190 o C, the fragmentation of particles became fairly pronounced so that the specific surface area of the pretreated material grew substantially. Meanwhile, almost all hemicellulose was removed from bagasse and the crystalline structure of cellulose disappeared. In contrast, the feature of lignin was remained clearly. However, a comparison between the heating times of 5 and 10 min revealed that the influence of the heating time on the lignocellulosic structure was not significant, indicating that the pretreatment with 5 min was sufficiently long.

Protein Molecular Structures, Protein SubFractions, and Protein Availability Affected by Heat Processing: A Review

International Nuclear Information System (INIS)

Yu, P.

2007-01-01

The utilization and availability of protein depended on the types of protein and their specific susceptibility to enzymatic hydrolysis (inhibitory activities) in the gastrointestine and was highly associated with protein molecular structures. Studying internal protein structure and protein subfraction profiles leaded to an understanding of the components that make up a whole protein. An understanding of the molecular structure of the whole protein was often vital to understanding its digestive behavior and nutritive value in animals. In this review, recently obtained information on protein molecular structural effects of heat processing was reviewed, in relation to protein characteristics affecting digestive behavior and nutrient utilization and availability. The emphasis of this review was on (1) using the newly advanced synchrotron technology (S-FTIR) as a novel approach to reveal protein molecular chemistry affected by heat processing within intact plant tissues; (2) revealing the effects of heat processing on the profile changes of protein subfractions associated with digestive behaviors and kinetics manipulated by heat processing; (3) prediction of the changes of protein availability and supply after heat processing, using the advanced DVE/OEB and NRC-2001 models, and (4) obtaining information on optimal processing conditions of protein as intestinal protein source to achieve target values for potential high net absorbable protein in the small intestine. The information described in this article may give better insight in the mechanisms involved and the intrinsic protein molecular structural changes occurring upon processing.

Painful tonic heat stimulation induces GABA accumulation in the prefrontal cortex in man

DEFF Research Database (Denmark)

Kupers, Ron; Danielsen, Else R; Kehlet, Henrik

2009-01-01

Relatively little is known on pain-induced neurotransmitter release in the human cerebral cortex. We used proton magnetic resonance spectroscopy (1H-MRS) during tonic painful heat stimulation to test the hypothesis of increases in both glutamate and GABA, two neurotransmitters with a key role...... that GABA is released in the human cerebral cortex during painful stimulation. The results are in line with animal findings on the role of GABA in pain processing and with studies in humans showing analgesic efficacy of GABA-related drugs in clinical pain conditions....... in pain processing. Using a 3T MR scanner, we acquired spectra from the rostral anterior cingulate cortex (rACC) in 13 healthy right-handed subjects at rest and during painful heat stimulation. The painful stimulus consisted of a suprathreshold painful tonic heat pulse, which was delivered to the right...

Intermediate heat exchanger tube vibration induced by cross and parallel mixed flow

International Nuclear Information System (INIS)

Kawamura, Koji

1986-01-01

The characteristics of pool type LMFBR intermediate heat exchanger (IHX) tube vibrations induced by cross and parallel mixed flow were basically investigated. Secondary coolant in IHX tube bundle is mixed flow of parallel jit flow along the tube axis through flow holes in baffle plates and cross flow. By changing these two flow rate, flow distributions vary in the tube bundle. Mixed flow also induces vibrations which cause fretting wear and fatigue of tube. It is therefore very important to evaluate the tube vibration characteristics for estimating the tube integrity. The results show that the relationships between tube vibrations and flow distributions in the tube bundle were cleared, and mixed flow induced tube vibration could be evaluated on the base of the characteristics of both parallel and cross flow induced vibration. From these investigations it could be concluded that the characteristics of tube vibration for various flow distributions can be systematically evaluated. (author)

Anomalous plasma heating induced by modulation of the current-density profile

International Nuclear Information System (INIS)

Lopes Cardozo, N.J.

1985-05-01

The usual plasma heating in a tokamak needs additional heating to reach ignition temperature (approx. 10 8 K). The method used in the TORTUR III experiment is to induce anomalous plasma resistivity by applying a short (10 microseconds) high-voltage pulse. A sharp rise of the plasma temperature is found almost simultaneously, but this effect, though considerable, is too short-lived to be of interest for a thermonuclear chain reaction. A second pulse gives a second rise of temperature, but this time a slow one, extending over several milliseconds. The mechanism of this delayed heating and the reservoir within the plasma supplying the energy are subjects of investigation in the TORTUR III experiments. Some conclusions concerning the plasma heating mechanism are presented. The conclusion is reached that the application of the high-voltage pulse results in a modulation of the current-density profile: the (normally already peaked) profile sharpens, the current concentrates in the centre of the plasma column. This is a non-equilibrium situation. It relaxes to the noraml current distribution within approximately 2 milliseconds. As long as this relaxation process is not finished, the dissipation is on an enhanced level and anomalous plasma heating is observed. Many plasma parameters are surveyed and evaluated: temperature (both of the ions and the electrons), density, emission spectrum (from microwaves to hard X-rays) and the fluctuation spectrum. Main subject of this report is the measurement and interpretation of the X-rays of the emission spectrum. Experimental results are presented and discussed

Salinization in a stratified aquifer induced by heat transfer from well casings

Science.gov (United States)

van Lopik, Jan H.; Hartog, Niels; Zaadnoordijk, Willem Jan; Cirkel, D. Gijsbert; Raoof, Amir

2015-12-01

The temperature inside wells used for gas, oil and geothermal energy production, as well as steam injection, is in general significantly higher than the groundwater temperature at shallower depths. While heat loss from these hot wells is known to occur, the extent to which this heat loss may result in density-driven flow and in mixing of surrounding groundwater has not been assessed so far. However, based on the heat and solute effects on density of this arrangement, the induced temperature contrasts in the aquifer due to heat transfer are expected to destabilize the system and result in convection, while existing salt concentration contrasts in an aquifer would act to stabilize the system. To evaluate the degree of impact that may occur under field conditions, free convection in a 50-m-thick aquifer driven by the heat loss from penetrating hot wells was simulated using a 2D axisymmetric SEAWAT model. In particular, the salinization potential of fresh groundwater due to the upward movement of brackish or saline water in a stratified aquifer is studied. To account for a large variety of well applications and configurations, as well as different penetrated aquifer systems, a wide range of well temperatures, from 40 to 100 °C, together with a range of salt concentration (1-35 kg/m3) contrasts were considered. This large temperature difference with the native groundwater (15 °C) required implementation of a non-linear density equation of state in SEAWAT. We show that density-driven groundwater flow results in a considerable salt mass transport (up to 166,000 kg) to the top of the aquifer in the vicinity of the well (radial distance up to 91 m) over a period of 30 years. Sensitivity analysis showed that density-driven groundwater flow and the upward salt transport was particularly enhanced by the increased heat transport from the well into the aquifer by thermal conduction due to increased well casing temperature, thermal conductivity of the soil, as well as decreased

Turbulence-induced heat transfer in PBMR core using LES and RANS

International Nuclear Information System (INIS)

Lee, Jung-Jae; Yoon, Su-Jong; Park, Goon-Cherl; Lee, Won-Jae

2007-01-01

This paper introduces the results of numerical simulations on flow fields and relevant heat transfer in the pebble bed reactor (PBR) core, since the coolant passes a highly complicated random flow path with a high Reynolds number, an appropriate treatment of the turbulence is required. A set of simple experiments for the flow over a circular cylinder with heat transfer was conducted to finally select the large eddy simulation (LES) and k-ω model among the considering Reynolds-averaged Navier-Stokes (RANS) models for PBR application. Using these models, the PBR cores, whose geometries were simplified to the body-centered cubical (BCC) and face-centered cubical (FCC) structures, were simulated. A larger pressure drop, a more random flow field, a higher vorticity magnitude and a higher temperature at the local hot spots on the pebble surface were found in the results of the LES than in those of RANS for both geometries. In cases of the LES, the flow structures were resolved up to the grid scales. Irregular distributions of the flow and local heat transfer were found in the BCC core, while relatively regular distributions for the FCC core. The turbulent nature of the coolant flow in the pebble core evidently affected the fuel surface temperature distribution. (author)

Drosophila UNC-45 prevents heat-induced aggregation of skeletal muscle myosin and facilitates refolding of citrate synthase

Energy Technology Data Exchange (ETDEWEB)

Melkani, Girish C.; Lee, Chi F.; Cammarato, Anthony [Department of Biology and the Molecular Biology Institute, San Diego State University, San Diego, CA 92182-4614 (United States); Bernstein, Sanford I., E-mail: sbernst@sciences.sdsu.edu [Department of Biology and the Molecular Biology Institute, San Diego State University, San Diego, CA 92182-4614 (United States)

2010-05-28

UNC-45 belongs to the UCS (UNC-45, CRO1, She4p) domain protein family, whose members interact with various classes of myosin. Here we provide structural and biochemical evidence that Escherichia coli-expressed Drosophila UNC-45 (DUNC-45) maintains the integrity of several substrates during heat-induced stress in vitro. DUNC-45 displays chaperone function in suppressing aggregation of the muscle myosin heavy meromyosin fragment, the myosin S-1 motor domain, {alpha}-lactalbumin and citrate synthase. Biochemical evidence is supported by electron microscopy, which reveals the first structural evidence that DUNC-45 prevents inter- or intra-molecular aggregates of skeletal muscle heavy meromyosin caused by elevated temperatures. We also demonstrate for the first time that UNC-45 is able to refold a denatured substrate, urea-unfolded citrate synthase. Overall, this in vitro study provides insight into the fate of muscle myosin under stress conditions and suggests that UNC-45 protects and maintains the contractile machinery during in vivo stress.

Comparison of two mathematical models for describing heat-induced cell killing

International Nuclear Information System (INIS)

Roti Roti, J.L.; Henle, K.J.

1980-01-01

A computer-based minimization algorithm is utilized to obtain the optimum fits of two models to hyperthermic cell killing data. The models chosen are the multitarget, single-hit equation, which is in general use, and the linear-quadratic equation, which has been applied to cell killing by ionizing irradiation but not to heat-induced cell killing. The linear-quadratic equation fits hyperthermic cell killing data as well as the multitarget, single-hit equation. Both parameters of the linear-quadratic equation obey the Arrhenius law, whereas only one of the two parameters of the multitarget, single-hit equation obeys the Arrhenius law. Thus the linear-quadratic function can completely define cell killing as a function of both time and temperature. In addition, the linear-quadratic model will provide a simplified approach to the study of the synergism between heat and X irradiation

Influence of Alpha Tocopherol on Heat Stress-Induced Changes in the Reproductive Function of Swiss Albino Mice

International Nuclear Information System (INIS)

AlEnazi, Maher M.

2007-01-01

The present study was carried out to investigate the influence of vitamin E (alpha-tocopherol) on heat stress-induced changes in the reproduction of Swiss albino mice. The evaluated parameters include: the estrous cycle, fertility, post-implantation losses of fetuses and estimation of progesterone levels in the serum. Eight groups of experimental mice (10 each) were used. Groups 1-4 (24 degree C) consisted of a control and alpha-tocopherol (100, 200 and 400 mg/kg) treated groups. Groups 5-8 (42 degree C) consisted of a positive control and alpha-tocopherol (100, 200 and 400 mg/kg) treated group. Heat-stress reduced significantly (p > 0.001) the number of fetuses and corpora lutea. There was also a significant decrease in the mean weights of fetuses (p > 0.001) and placenta (p > 0.01) in the heat-stress group with a decrease in their serum progesterone levels (p > 0.01). Heat-stress groups treated with high doses of alpha-tocopherol 200 and 400 mg/kg, showed protection against heat-stress related abnormalities. The results showed that alpha-tocopherol plays a role in protection against hyperthermia induced changes in the estrous cycle length, infertility, post-implantation losses and depletion in the serum level of progesterone. (author)

Effects of heating on composition, degree of darkness, and stacking nanostructure of soil humic acids

Energy Technology Data Exchange (ETDEWEB)

Katsumi, Naoya, E-mail: n-katsu@ishikawa-pu.ac.jp; Yonebayashi, Koyo; Okazaki, Masanori

2016-01-15

Wildfires and prescribed burning can affect both the quality and the quantity of organic matter in soils. In this study, we investigated qualitative and quantitative changes of soil humic substances in two different soils (an Entisol from a paddy field and an Inceptisol from a cedar forest) under several controlled heating conditions. Soil samples were heated in a muffle furnace at 200, 250, or 300 °C for 1, 3, 5, or 12 h. The humic acid and fulvic acid contents of the soil samples prior to and after heating were determined. The degree of darkness, elemental composition, carbon and nitrogen stable isotope ratios, {sup 13}C nuclear magnetic resonance spectra, and X-ray diffraction patterns of humic acids extracted from the soils before and after heating were measured. The proportion of humic acids in total carbon decreased with increasing heating time at high temperature (300 °C), but increased with increasing heating time at ≤ 250 °C. The degree of darkness of the humic acids increased with increasing heating time and temperature. During darkening, the H/C atomic ratios, the proportion of aromatic C, and the carbon and nitrogen stable isotope ratios increased, whereas the proportions of alkyl C and O-alkyl C decreased. X-ray diffraction analysis verified that a stacking nanostructure developed by heating. Changes in the chemical structure of the humic acids from the heated soils depended on the type of soil. The major structural components of the humic acids from the heated Entisol were aromatic C and carboxylic C, whereas aliphatic C, aromatic C, and carboxylic C structural components were found in the humic acids from the heated Inceptisol. These results suggest that the heat-induced changes in the chemical structure of the humic acids depended on the source plant. - Highlights: • Darkness of humic acids increased with increasing heating time and temperature. • Aromatic carbon content increased during darkening. • Carbon and nitrogen stable isotope

Electrically heated 3D-macro cellular SiC structures for ignition and combustion application

International Nuclear Information System (INIS)

Falgenhauer, Ralf; Rambacher, Patrick; Schlier, Lorenz; Volkert, Jochen; Travitzky, Nahum; Greil, Peter; Weclas, Miroslaw

2017-01-01

Highlights: • 3D-printed macro cellular SiC structure. • Directly integrated electrically heated ignition element used in combustion reactor. • Experimental investigation of the ignition process. - Abstract: The paper describes different aspects of porous combustion reactor operation especially at cold start conditions. Under cold start conditions it is necessary to increase the internal energy of the combustion reactor, to accumulate enough energy inside its solid phase and to reach at least the ignition temperature on the reactors inner surface. The most practicable method to preheat a cold porous reactor is to use its surface as a flame holder and to apply free flame combustion as a heat source for the preheating process. This paper presents a new electrically heated ignition element, which gets integrated in a three dimensional macro-cellular SiSiC reactor structure. For the development of the ignition element it was assumed, that the element is made of the same material as the combustion reactor itself and is fully integrated within the three-dimensional macro-cellular structure of the combustion reactor. Additive manufacturing like three-dimensional (3D) printing permits the production of regular SiSiC structures with constant strut thickness and a defined current flow path. To get a controlled temperature distribution on the ignition element it is necessary to control the current density distribution in the three-dimensional macro-cellular reactor structure. The ignition element used is designed to be an electrical resistance in an electric current system, converting flowing current into heat with the goal to get the highest temperature in the ignition region (glow plug). First experiments show that the ignition element integrated in a combustion reactor exhibits high dynamics and can be heated to the temperatures much above 1000 °C in a very short time (approx. 800 ms) for current of I = 150 A.

Study of the structure and development of the set of reference materials of composition and structure of heat resisting nickel and intermetallic alloys

Directory of Open Access Journals (Sweden)

E. B. Chabina

2016-01-01

Full Text Available Relevance of research: There are two sizes (several microns and nanodimensional of strengthening j'-phase in single-crystal heat resisting nickel and intermetallic alloys, used for making blades of modern gas turbine engines (GTD. For in-depth study of structural and phase condition of such alloys not only qualitative description of created structure is necessary, but quantitative analysis of alloy components geometrical characteristics. Purpose of the work: Development of reference material sets of heat resisting nickel and intermetallic alloy composition and structure. Research methods: To address the measurement problem of control of structural and geometrical characteristics of single-crystal heat resisting and intermetallic alloys by analytical microscopy and X-ray diffraction analysis the research was carried out using certified measurement techniques on facilities, entered in the Register of Measurement Means of the Russian Federation. The research was carried out on microsections, foils and plates, cut in the plane {100}. Results: It is established that key parameters, defining the properties of these alloys are particle size of strengthening j' -phase, the layer thickness of j-phase between them and parameters of phases lattice. Metrological requirements for reference materials of composition and structure of heat resisting nickel and intermetallic alloys are formulated. The necessary and sufficient reference material set providing the possibility to determine the composition and structure parameters of single-crystal heat resisting nickel and intermetallic alloys is defined. The developed RM sets are certified as in-plant reference materials. Conclusion: The reference materials can be used for graduation of spectral equipment when conducting element analysis of specified class alloys; for calibration of means of measuring alloy structure parameters; for measurement of alloys phases lattice parameters; for structure reference pictures

Optimization design of LED heat dissipation structure based on strip fins

Science.gov (United States)

Xue, Lingyun; Wan, Wenbin; Chen, Qingguang; Rao, Huanle; Xu, Ping

2018-03-01

To solve the heat dissipation problem of LED, a radiator structure based on strip fins is designed and the method to optimize the structure parameters of strip fins is proposed in this paper. The combination of RBF neural networks and particle swarm optimization (PSO) algorithm is used for modeling and optimization respectively. During the experiment, the 150 datasets of LED junction temperature when structure parameters of number of strip fins, length, width and height of the fins have different values are obtained by ANSYS software. Then RBF neural network is applied to build the non-linear regression model and the parameters optimization of structure based on particle swarm optimization algorithm is performed with this model. The experimental results show that the lowest LED junction temperature reaches 43.88 degrees when the number of hidden layer nodes in RBF neural network is 10, the two learning factors in particle swarm optimization algorithm are 0.5, 0.5 respectively, the inertia factor is 1 and the maximum number of iterations is 100, and now the number of fins is 64, the distribution structure is 8*8, and the length, width and height of fins are 4.3mm, 4.48mm and 55.3mm respectively. To compare the modeling and optimization results, LED junction temperature at the optimized structure parameters was simulated and the result is 43.592°C which approximately equals to the optimal result. Compared with the ordinary plate-fin-type radiator structure whose temperature is 56.38°C, the structure greatly enhances heat dissipation performance of the structure.

The effect of air permeability characteristics of protective garments on the induced physiological strain under exercise-heat stress.

Science.gov (United States)

Epstein, Yoram; Heled, Yuval; Ketko, Itay; Muginshtein, Jeni; Yanovich, Ran; Druyan, Amit; Moran, Daniel S

2013-08-01

The high values of thermal resistance (Rct) and/or vapor resistance (Ret) of chemical protective clothing (CPC) induce a considerable thermal stress. The present study compared the physiological strain induced by CPCs and evaluates the relative importance of the fabrics' Rct, Ret, and air permeability in determining heat strain. Twelve young (20-30 years) healthy, heat-acclimated male subjects were exposed fully encapsulated for 3h daily to an exercise-heat stress (35°C and 30% relative humidity, walking on a motor-driven treadmill at a pace of 5 km h(1) and a 4% inclination, in a work-rest cycle of 45 min work and 15 min rest). Two bipack CPCs (PC1 and PC2) were tested and the results were compared with those attained by two control suits-a standard cotton military BDU (CO1) and an impermeable material suit (CO2). The physiological burden imposed by the two bilayer garments was within the boundaries set by the control conditions. Overall, PC2 induced a lower strain, which was closer to CO1, whereas PC1 was closer to CO2. Air permeability of the PC2 cloth was almost three times higher than that of PC1, enabling a better heat dissipation and consequently a lower physiological strain. Furthermore, air permeability characteristic of the fabrics, which is associated with its construction and weave, significantly correlated with the physiological strain, whereas the correlation with Rct, Ret, and weight was poor. The results emphasize the importance of air permeability in reducing the physiological strain induced by CPCs.

Tube sheet structural analysis of intermediate heat exchanger for fast breeder reactor 'Monju'

International Nuclear Information System (INIS)

Nakagawa, Y.; Ueno, T.; Fukuda, Y.; Ichimiya, M.

1983-01-01

The Prototype Fast Breeder Reactor 'Monju' is the first power generating fast breeder reactor in Japan. We have been designing the components of the plant for manufacturing. Among these is the intermediate heat exchanger (IHX) which exchanges heat between primary and secondary sodium loop. The tube sheet of IHX (shell to ligament junction) is a difficult area from the view point of structural strength design under elevated temperature. To validate the structural integrity of tube sheet we performed the series of inelastic analysis and tube sheet thermal shock test using test pieces and half scale model of actual design. The results of inelastic analyses showed there is little progressive deformation around shell to ligament structural discontinuous junction. Furthermore, thermal shock tests showed no increase of an accumulative deformation. By these analyses and experiments, structural reliability of tube sheet could be shown. (author)

Shear structuring as a new method to make anisotropic structures from soy-gluten blends

NARCIS (Netherlands)

Grabowska, K.J.; Tekidou, S.; Boom, R.M.; Goot, van der A.J.

2014-01-01

The concept of shear-induced structuring was applied to concentrated blends of soy protein isolate (SPI) and wheat gluten (WG) to create novel semi-solid food textures. Concurrent simple shear deformation and heating (95 °C) of the protein blends generated original structures consisting of fibers or

Reversible Heat-Induced Inactivation of Chimeric β-Glucuronidase in Transgenic Plants1

Science.gov (United States)

Almoguera, Concepción; Rojas, Anabel; Jordano, Juan

2002-01-01

We compared the expression patterns in transgenic tobacco (Nicotiana tabacum) of two chimeric genes: a translational fusion to β-glucuronidase (GUS) and a transcriptional fusion, both with the same promoter and 5′-flanking sequences of Ha hsp17.7 G4, a small heat shock protein (sHSP) gene from sunflower (Helianthus annuus). We found that immediately after heat shock, the induced expression from the two fusions in seedlings was similar, considering chimeric mRNA or GUS protein accumulation. Surprisingly, we discovered that the chimeric GUS protein encoded by the translational fusion was mostly inactive in such conditions. We also found that this inactivation was fully reversible. Thus, after returning to control temperature, the GUS activity was fully recovered without substantial changes in GUS protein accumulation. In contrast, we did not find differences in the in vitro heat inactivation of the respective GUS proteins. Insolubilization of the chimeric GUS protein correlated with its inactivation, as indicated by immunoprecipitation analyses. The inclusion in another chimeric gene of the 21 amino-terminal amino acids from a different sHSP lead to a comparable reversible inactivation. That effect not only illustrates unexpected post-translational problems, but may also point to sequences involved in interactions specific to sHSPs and in vivo heat stress conditions. PMID:12011363

Measurement of heat treatment induced residual stresses by using ESPI combined with hole-drilling method

Directory of Open Access Journals (Sweden)

Jie Cheng

2010-08-01

Full Text Available In this study, residual stresses in heat treated specimen were measured by using ESPI (Electronic Speckle-Pattern Interferometry combined with the hole-drilling method. The specimen, made of SUS 304 austenitic stainless steel, was quenched and water cooled to room temperature. Numerical simulation using a hybrid FDM/FEM package was also carried out to simulate the heat treatment process. As a result, the thermal stress fields were obtained from both the experiment and the numerical simulation. By comparision of stress fields, results from the experimental method and numerical simulation well agreed to each other, therefore, it is proved that the presented experimental method is applicable and reliable for heat treatment induced residual stress measurement.

Beam induced heating reduction by bunch flattening

CERN Document Server

Argyropoulos, T; Esteban Müller, JF; Jakobsen, S; Mastoridis, T; Metral, E; Mounet, N; Papotti, G; Pieloni, T; Salvant, B; Shaposhnikova, E; Timko, H

2014-01-01

The main purpose of this MD was to modify the beam induced heating on some critical LHC components by flattening the bunch distribution by applying an RF phase modulation. In this way, the beam spectrum was modified so that the power spectral density is reduced at low frequencies (below 1.1 GHz), which is the band of frequencies where the beam interaction with different component impedances is most critical. We present temperature measurements showing the beneficial effect of this latter distribution on some of the monitored devices. Longitudinal peak detected Schottky spectrum was also acquired during the first part of the MD with the intention of estimating the synchrotron frequency shift due to the reactive part of the longitudinal impedance. In the second part of the MD, an attempt to cure the transverse instability during the beta-squeeze was done by reducing the RF voltage to lengthen the bunches and enhance Landau Damping.

Possible Contribution of Zerumbone-Induced Proteo-Stress to Its Anti-Inflammatory Functions via the Activation of Heat Shock Factor 1.

Directory of Open Access Journals (Sweden)

Yoko Igarashi

Full Text Available Zerumbone is a sesquiterpene present in Zinger zerumbet. Many studies have demonstrated its marked anti-inflammatory and anti-carcinogenesis activities. Recently, we showed that zerumbone binds to numerous proteins with scant selectivity and induces the expression of heat shock proteins (HSPs in hepatocytes. To dampen proteo-toxic stress, organisms have a stress-responsive molecular machinery, known as heat shock response. Heat shock factor 1 (HSF1 plays a key role in this protein quality control system by promoting activation of HSPs. In this study, we investigated whether zerumbone-induced HSF1 activation contributes to its anti-inflammatory functions in stimulated macrophages. Our findings showed that zerumbone increased cellular protein aggregates and promoted nuclear translocation of HSF1 for HSP expression. Interestingly, HSF1 down-regulation attenuated the suppressive effects of zerumbone on mRNA and protein expressions of pro-inflammatory genes, including inducible nitric oxide synthase and interlukin-1β. These results suggest that proteo-stress induced by zerumbone activates HSF1 for exhibiting its anti-inflammatory functions.

Konjac flour improved textural and water retention properties of transglutaminase-mediated, heat-induced porcine myofibrillar protein gel: Effect of salt level and transglutaminase incubation.

Science.gov (United States)

Chin, Koo B; Go, Mi Y; Xiong, Youling L

2009-03-01

Functional properties of heat-induced gels prepared from microbial transglutaminase (TG)-treated porcine myofibrillar protein (MP) containing sodium caseinate with or without konjac flour (KF) under various salt concentrations (0.1, 0.3 and 0.6MNaCl) were evaluated. The mixed MP gels with KF exhibited improved cooking yields at all salt concentrations. TG treatment greatly enhanced gel strength and elasticity (storage modulus, G') at 0.6M NaCl, but not at lower salt concentrations. The combination of KF and TG improved the gel strength at 0.1 and 0.3M NaCl and G' at all salt concentrations, when compared with non-TG controls. Incubation of MP suspensions (sols) with TG promoted the disappearance of myosin heavy chain and the production of polymers. The TG-treated MP mixed gels had a compact structure, compared to those without TG, and the KF incorporation modified the gel matrix and increased its water-holding capacity. Results from differential scanning calorimetry suggested possible interactions of MP with KF, which may explain the changes in the microstructure of the heat-induced gels.

Phorbol ester tumor promoter induced the synthesis of two major cytoplasmic proteins: identity with two proteins induced under heat-shocked and glucose-starved conditions

International Nuclear Information System (INIS)

Zhang, H.; Chen, K.Y.; Liu, A.Y.C.

1987-01-01

The regulation of specific protein synthesis by the phorbol ester tumor promoter, 12-O-tetradecanoyl-phorbol-13-acetate (TPA), was evaluated using the L-8 and C-2 myoblast and the 3T3-L1 fibroblast cell cultures. TPA increased, by 2-4 fold, the synthesis rates of two cytoplasmic proteins with apparent molecular weights of 89,000 and 74,000 as determined by SDS-polyacrylamide gel electrophoresis and autoradiography. The concentration of TPA and the time of incubation needed to elicit this induction was determined to be 10 μg/ml and 20 hrs, respectively. Increasing the concentration of TPA to 100, 200, and 500 ng/ml did not result in a greater magnitude of induction. The possibility that these two TPA-induced proteins may be identical to proteins with similar molecular weights induced under heat-shocked or glucose-starved conditions was evaluated by 1-D and 2-D gel electrophoresis and autoradiography. Results provided evidence that the TPA-induced 89,000- and 74,000-dalton proteins were identical to hsp 89 and hsp 74, 2 out of a set of 8-9 proteins induced under heat shocked conditions. Furthermore, they are identical to two of the set of glucose-regulated proteins induced under a glucose-starved condition

The deregulation effects of Finnish electricity markets on district heating prices

International Nuclear Information System (INIS)

Linden, Mikael; Peltola-Ojala, Paeivi

2010-01-01

This paper investigates an empirical econometric panel data model in order to test deregulation and regional market structure effects on district heating prices in Finland for period 1996-2002. The data was collected from 76 district heating firms throughout Finland. Special emphasis is placed on the modeling of policy-induced competition, which began in year 1999, regional based fuel selection, local market structures, and distribution network sharing effects. The results imply that the local structures of energy production and sales have an important role to play in the formation of market prices and that the price lowering effects of energy market deregulation are permanent. (author)

Linking lowermost mantle structure, core-mantle boundary heat flux and mantle plume formation

Science.gov (United States)

Li, Mingming; Zhong, Shijie; Olson, Peter

2018-04-01

The dynamics of Earth's lowermost mantle exert significant control on the formation of mantle plumes and the core-mantle boundary (CMB) heat flux. However, it is not clear if and how the variation of CMB heat flux and mantle plume activity are related. Here, we perform geodynamic model experiments that show how temporal variations in CMB heat flux and pulses of mantle plumes are related to morphologic changes of the thermochemical piles of large-scale compositional heterogeneities in Earth's lowermost mantle, represented by the large low shear velocity provinces (LLSVPs). We find good correlation between the morphologic changes of the thermochemical piles and the time variation of CMB heat flux. The morphology of the thermochemical piles is significantly altered during the initiation and ascent of strong mantle plumes, and the changes in pile morphology cause variations in the local and the total CMB heat flux. Our modeling results indicate that plume-induced episodic variations of CMB heat flux link geomagnetic superchrons to pulses of surface volcanism, although the relative timing of these two phenomena remains problematic. We also find that the density distribution in thermochemical piles is heterogeneous, and that the piles are denser on average than the surrounding mantle when both thermal and chemical effects are included.

Multi-crease Self-folding by Global Heating.

Science.gov (United States)

Miyashita, Shuhei; Onal, Cagdas D; Rus, Daniela

2015-01-01

This study demonstrates a new approach to autonomous folding for the body of a 3D robot from a 2D sheet, using heat. We approach this challenge by folding a 0.27-mm sheetlike material into a structure. We utilize the thermal deformation of a contractive sheet sandwiched by rigid structural layers. During this baking process, the heat applied on the entire sheet induces contraction of the contracting layer and thus forms an instructed bend in the sheet. To attain the targeted folding angles, the V-fold spans method is used. The targeted angle θout can be kinematically encoded into crease geometry. The realization of this angle in the folded structure can be approximately controlled by a contraction angle θin. The process is non-reversible, is reliable, and is relatively fast. Our method can be applied simultaneously to all the folds in multi-crease origami structures. We demonstrate the use of this method to create a lightweight mobile robot.

Joule heating induced stream broadening in free-flow zone electrophoresis.

Science.gov (United States)

Dutta, Debashis

2018-03-01

The use of an electric field in free-flow zone electrophoresis (FFZE) automatically leads to Joule heating yielding a higher temperature at the center of the separation chamber relative to that around the channel walls. For small amounts of heat generated, this thermal effect introduces a variation in the equilibrium position of the analyte molecules due to the dependence of liquid viscosity and analyte diffusivity on temperature leading to a modification in the position of the analyte stream as well as the zone width. In this article, an analytic theory is presented to quantitate such effects of Joule heating on FFZE assays in the limit of small temperature differentials across the channel gap yielding a closed form expression for the stream position and zone variance under equilibrium conditions. A method-of-moments approach is employed to develop this analytic theory, which is further validated with numerical solutions of the governing equations. Interestingly, the noted analyses predict that Joule heating can drift the location of the analyte stream either way of its equilibrium position realized in the absence of any temperature rise in the system, and also tends to reduce zone dispersion. The extent of these modifications, however, is governed by the electric field induced temperature rise and three Péclet numbers evaluated based on the axial pressure-driven flow, transverse electroosmotic and electrophoretic solute velocities in the separation chamber. Monte Carlo simulations of the FFZE system further establish a time and a length scale over which the results from the analytic theory are valid. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Nanoimprinted polymer chips for light induced local heating of liquids in micro- and nanochannels

DEFF Research Database (Denmark)

Thamdrup, Lasse Højlund; Pedersen, Jonas Nyvold; Flyvbjerg, Henrik

2010-01-01

A nanoimprinted polymer chip with a thin near-infrared absorber layer that enables light-induced local heating (LILH) of liquids inside micro- and nanochannels is presented. An infrared laser spot and corresponding hot-spot could be scanned across the device. Large temperature gradients yield...... a 785 nm laser diode was focused from the backside of the chip to a spot diameter down to 5 ..m in the absorber layer, yielding a localized heating (Gaussian profile) and large temperature gradients in the liquid in the nanochannels. A laser power of 38 mW yielded a temperature of 40°C in the center...

Neurotoxicity induced by arsenic in Gallus Gallus: Regulation of oxidative stress and heat shock protein response.

Science.gov (United States)

Zhao, Panpan; Guo, Ying; Zhang, Wen; Chai, Hongliang; Xing, Houjuan; Xing, Mingwei

2017-01-01

Arsenic, a naturally occurring heavy metal pollutant, is one of the functioning risk factors for neurological toxicity in humans. However, little is known about the effects of arsenic on the nervous system of Gallus Gallus. To investigate whether arsenic induce neurotoxicity and influence the oxidative stress and heat shock proteins (Hsps) response in chickens, seventy-two 1-day-old male Hy-line chickens were treated with different doses of arsenic trioxide (As 2 O 3 ). The histological changes, antioxidant enzyme activity, and the expressions of Hsps were detected. Results showed slightly histology changes were obvious in the brain tissues exposure to arsenic. The activities of Glutathione peroxidase (GSH-Px) and catalase (CAT) were decreased compared to the control, whereas the malondialdehyde (MDA) content was increased gradually along with increase in diet-arsenic. The mRNA levels of Hsps and protein expressions of Hsp60 and Hsp70 were up-regulated. These results suggested that sub-chronic exposure to arsenic induced neurotoxicity in chickens. Arsenic exposure disturbed the balance of oxidants and antioxidants. Increased heat shock response tried to protect chicken brain tissues from tissues damage caused by oxidative stress. The mechanisms of neurotoxicity induced by arsenic include oxidative stress and heat shock protein response in chicken brain tissues. Copyright © 2016 Elsevier Ltd. All rights reserved.

RALOC Mod 1/81: Program description of RALOC version by the structural heat model HECU

International Nuclear Information System (INIS)

Pham, V.T.

1984-01-01

In the version RALOC-Mod 1/81 an expanded heat transfer model and structure heat model is included. This feature allows for a realistic simulation of the thermodynamic and fluiddynamic characteristics of the containment atmosphere. Steel and concrete substructures with a plain or rotational symmetry can be represented. The treat transfer calculations for the structures are problem oriented, taking into account, the time- and space dependencies. The influence of the heat transfer on the gas transport (in particular convection) in the reactor vessel is demonstrated by the numerical calculations. In contrast to the calculations without a simulation of the heat storage effects of the container structures showing a widely homogenious hydrogen distribution, the results on the basis of the HECU-model give an inhomogenious distribution during the first 8 to 12 days. However these results are only examples for the application of the RALOC-Mod 1/81 -code, which have not been intended to contribute to the discussion of hydrogen distributions in a PWR-type reactor. (orig./GL) [de

Modern thermodynamics from heat engines to dissipative structures

CERN Document Server

Kondepudi, Dilip

2014-01-01

Modern Thermodynamics: From Heat Engines to Dissipative Structures, Second Edition presents a comprehensive introduction to 20th century thermodynamics that can be applied to both equilibrium and non-equilibrium systems, unifying what was traditionally divided into 'thermodynamics' and 'kinetics' into one theory of irreversible processes. This comprehensive text, suitable for introductory as well as advanced courses on thermodynamics, has been widely used by chemists, physicists, engineers and geologists.  Fully revised and expanded, this new edition includes the following updates and featur

Increased synaptophysin is involved in inflammation-induced heat hyperalgesia mediated by cyclin-dependent kinase 5 in rats.

Directory of Open Access Journals (Sweden)

Hong-Hai Zhang

Full Text Available Mechanisms associated with cyclin-dependent kinase 5 (Cdk5-mediated heat hyperalgesia induced by inflammation remain undefined. This study was designed to examine whether Cdk5 mediates heat hyperalgesia resulting from peripheral injection of complete Freund's adjuvant (CFA in the spinal dorsal horns of rats by interacting with synaptophysin, a well known membrane protein mediating the endocytosis-exocytosis cycle of synaptic vesicles as a molecular marker associated with presynaptic vesicle membranes. The role of Cdk5 in mediating synaptophysin was examined through the combined use of behavioral approaches, imaging studies, and immunoprecipitation following CFA-induced inflammatory pain. Results showed that Cdk5 colocalized with both synaptophysin and soluble N-ethylmaleimide-sensitive factor (NSF attachment protein receptors (SNAREs consisting of VAMP-2, SNAP-25, and syntaxin 1A in spinal dorsal horn of rats. Increased synaptophysin expression of spinal cord horn neurons post intraplantar injection of CFA coincided with increased duration of heat hyperalgesia lasting from 6 h to 3 d. Intrathecal administration of roscovitine, a Cdk5 specific inhibitor, significantly depressed synaptophysin expression during peak heat hyperalgesia and heat hyperalgesia induced by peripheral injection of CFA. Data presented in this report indicated that calpain activity was transiently upregulated 6 h post CFA-treatment despite previous reports suggesting that calpain was capable of cleaving p35 into p25. Results from previous studies obtained by other laboratories demonstrated that significant changes in p35 expression levels within spinal cord horn neurons were not observed in the CFA-treated inflammatory pain model although significant upregulation of Cdk5 kinase was observed between 2 h to 7 d. Therefore, generation of p25 occurred in a calpain-independent fashion in a CFA-treated inflammatory pain model. Our results demonstrated that increased synaptophysin

HEAT INDUCIBLE EXPRESSION OF ANTIFREEZE PROTEIN GENES FROM THE BEETLES Tenebrio molitor AND Microdera punctipennis.

Science.gov (United States)

Li, Jieqiong; Ma, Wenjing; Ma, Ji

2016-01-01

Antifreeze proteins (AFPs) play important roles in protecting poikilothermic organisms from cold damage. The expression of AFP genes (afps) is induced by low temperature. However, it is reported that heat can influence the expression of afps in the desert beetle Microdera punctipennis. To further detect whether heat also induce the expression of afps in other insects, and to determine the expression profiling of insect afps at different temperatures. The expression of antifreeze protein genes in the two beetles, Microdera punctipennis and Tenebrio molitor that have quite different living environment, under different temperatures were studied by using real-time quantitative PCR. Mild low temperatures (5~15 degree C), high temperature (38~47 degree C for M. punctipennis, or 37~42 degree C for T. molitor) and temperature difference (10~30 degree C) all stimulated strongly to the expression of AFP genes (Mpafps) in M. punctipennis which lives in the wild filed in desert. The mRNA level of Mpafps after M. punctipennis were exposed to these temperatures for 1h~5h was at least 30-fold of the control at 25 degree C. For T. molitor which is breeding in door with wheat bran all these temperatures stimulated significantly to the expression of Tmafps, while the extent and degree of the temperature stimulation on Tmafps expression were much lower than on Mpafps. After T. molitor were exposed to 5 degree C and 15 degree C for 1h~5h, the mRNA level of Tmafps was over 6-fold and 45-fold of the control at 25 degree C. High temperature (37~42 degree C) for 1h~3h treatments increased Tmafps mRNA level 4.8-fold of the control. Temperature difference of 10 degree C was effective in stimulating Tmafps expression. The expression of insect antifreeze protein genes both in M. punctipennis and T. molitor was induced by heat, suggesting that this phenomenon may be common in insects; the extent and degree of the influence differ in species that have different living conditions. The heat

Yeast cell inactivation related to local heating induced by low-intensity electric fields with long-duration pulses.

Science.gov (United States)

Guyot, Stéphane; Ferret, Eric; Boehm, Jean-Baptiste; Gervais, Patrick

2007-01-25

The effects of electric field (EF) treatments on Saccharomyces cerevisiae viability were investigated using a PG200 electroporator (Hoefer Scientific Instrument, San Fransisco, CA, USA) with specific attention to induced thermal effects on cell death. Lethal electric fields (1.5 kV cm(-1) for 5 s) were shown to cause heat variations in the cell suspension medium (water+glycerol), while corresponding classical thermal treatments at equivalent temperatures had no effect on the cells viability. Variations of the electrical conductivity of the intra- and extracellular matrix caused by ions and solutes transfer across the membrane were shown to be involved in the observed heating. The results permitted to build a theoretical model for the temperature variations induced by electric fields. Using this model and the electrical conductivity of the different media, a plausible explanation of the cell death induced by low-intensity electric fields with long-duration pulses has been proposed. Indeed, cell mortality could in part be caused by direct and indirect effects of electric fields. Direct effects are related to well known electromechanical phenomena, whereas indirect effects are related to secondary thermal stress caused by plasma membrane thermoporation. This thermoporation was attributed to electrical conductivity variations and the corresponding intracellular heating.

On the estimation of the worst-case implant-induced RF-heating in multi-channel MRI

Science.gov (United States)

Córcoles, Juan; Zastrow, Earl; Kuster, Niels

2017-06-01

The increasing use of multiple radiofrequency (RF) transmit channels in magnetic resonance imaging (MRI) systems makes it necessary to rigorously assess the risk of RF-induced heating. This risk is especially aggravated with inclusions of medical implants within the body. The worst-case RF-heating scenario is achieved when the local tissue deposition in the at-risk region (generally in the vicinity of the implant electrodes) reaches its maximum value while MRI exposure is compliant with predefined general specific absorption rate (SAR) limits or power requirements. This work first reviews the common approach to estimate the worst-case RF-induced heating in multi-channel MRI environment, based on the maximization of the ratio of two Hermitian forms by solving a generalized eigenvalue problem. It is then shown that the common approach is not rigorous and may lead to an underestimation of the worst-case RF-heating scenario when there is a large number of RF transmit channels and there exist multiple SAR or power constraints to be satisfied. Finally, this work derives a rigorous SAR-based formulation to estimate a preferable worst-case scenario, which is solved by casting a semidefinite programming relaxation of this original non-convex problem, whose solution closely approximates the true worst-case including all SAR constraints. Numerical results for 2, 4, 8, 16, and 32 RF channels in a 3T-MRI volume coil for a patient with a deep-brain stimulator under a head imaging exposure are provided as illustrative examples.

Remote Sensing-Based Characterization of Settlement Structures for Assessing Local Potential of District Heat

Directory of Open Access Journals (Sweden)

Michael Nast

2011-07-01

Full Text Available In Europe, heating of houses and commercial areas is one of the major contributors to greenhouse gas emissions. When considering the drastic impact of an increasing emission of greenhouse gases as well as the finiteness of fossil resources, the usage of efficient and renewable energy generation technologies has to be increased. In this context, small-scale heating networks are an important technical component, which enable the efficient and sustainable usage of various heat generation technologies. This paper investigates how the potential of district heating for different settlement structures can be assessed. In particular, we analyze in which way remote sensing and GIS data can assist the planning of optimized heat allocation systems. In order to identify the best suited locations, a spatial model is defined to assess the potential for small district heating networks. Within the spatial model, the local heat demand and the economic costs of the necessary heat allocation infrastructure are compared. Therefore, a first and major step is the detailed characterization of the settlement structure by means of remote sensing data. The method is developed on the basis of a test area in the town of Oberhaching in the South of Germany. The results are validated through detailed in situ data sets and demonstrate that the model facilitates both the calculation of the required input parameters and an accurate assessment of the district heating potential. The described method can be transferred to other investigation areas with a larger spatial extent. The study underlines the range of applications for remote sensing-based analyses with respect to energy-related planning issues.

The Influence of Knitting Structure on Heating and Cooling Dynamic

Directory of Open Access Journals (Sweden)

Daiva MIKUČIONIENĖ

2013-05-01

Full Text Available The comfort provided by clothing depends on several factors, one of them being thermal comfort. Human thermal comfort depends on a combination of clothing, climate, and physical activity. It is known, the fibre type, yarn properties, fabric structure, finishing are the main factors affecting thermo-physiological comfort. The thermal property of knitted fabric is very important not only for its thermal comfort but also for protection against cross weather conditions. Most of the studies carried out have been devoted to measure static thermal properties. But it is very important not only amount of the heat released to the environment but also the dynamics of the heat transmission. The main goal of this work was to investigate the dynamic of the heat and cool transfer through the fabrics with different knitting pattern and different type of the yarns. Three different types of knitted fabrics were developed for this experimental work.DOI: http://dx.doi.org/10.5755/j01.ms.19.2.4434

Heat exchanger device and method for heat removal or transfer

Science.gov (United States)

Koplow, Jeffrey P

2013-12-10

Systems and methods for a forced-convection heat exchanger are provided. In one embodiment, heat is transferred to or from a thermal load in thermal contact with a heat conducting structure, across a narrow air gap, to a rotating heat transfer structure immersed in a surrounding medium such as air.

Surface induces different crystal structures in a room temperature switchable spin crossover compound.

Science.gov (United States)

Gentili, Denis; Liscio, Fabiola; Demitri, Nicola; Schäfer, Bernhard; Borgatti, Francesco; Torelli, Piero; Gobaut, Benoit; Panaccione, Giancarlo; Rossi, Giorgio; Degli Esposti, Alessandra; Gazzano, Massimo; Milita, Silvia; Bergenti, Ilaria; Ruani, Giampiero; Šalitroš, Ivan; Ruben, Mario; Cavallini, Massimiliano

2016-01-07

We investigated the influence of surfaces in the formation of different crystal structures of a spin crossover compound, namely [Fe(L)2] (LH: (2-(pyrazol-1-yl)-6-(1H-tetrazol-5-yl)pyridine), which is a neutral compound thermally switchable around room temperature. We observed that the surface induces the formation of two different crystal structures, which exhibit opposite spin transitions, i.e. on heating them up to the transition temperature, one polymorph switches from high spin to low spin and the second polymorph switches irreversibly from low spin to high spin. We attributed this inversion to the presence of water molecules H-bonded to the complex tetrazolyl moieties in the crystals. Thin deposits were investigated by means of polarized optical microscopy, atomic force microscopy, X-ray diffraction, X-ray absorption spectroscopy and micro Raman spectroscopy; moreover the analysis of the Raman spectra and the interpretation of spin inversion were supported by DFT calculations.

Laser Heating of the Core-Shell Nanowires

Science.gov (United States)

Astefanoaei, Iordana; Dumitru, Ioan; Stancu, Alexandru

2016-12-01

The induced thermal stress in a heating process is an important parameter to be known and controlled in the magnetization process of core-shell nanowires. This paper analyses the stress produced by a laser heating source placed at one end of a core-shell type structure. The thermal field was computed with the non-Fourier heat transport equation using a finite element method (FEM) implemented in Comsol Multiphysics. The internal stresses are essentially due to thermal gradients and different expansion characteristics of core and shell materials. The stress values were computed using the thermo elastic formalism and are depending on the laser beam parameters (spot size, power etc.) and system characteristics (dimensions, thermal characteristics). Stresses in the GPa range were estimated and consequently we find that the magnetic state of the system can be influenced significantly. A shell material as the glass which is a good thermal insulator induces in the magnetic core, the smaller stresses and consequently the smaller magnetoelastic energy. These results lead to a better understanding of the switching process in the magnetic materials.

Kinetics of heat-induced color change of a tuna-vegetable mixture

OpenAIRE

Scherer, Erika; Sandoval, Aleida J; Barreiro, José A

2009-01-01

Heat induced color change kinetics in a tuna-vegetable mixture was evaluated by measuring color parameter "L" (Hunter-Lab) and 5-hydroxi-methyl-furfural (5-HMF) accumulation. For this purpose small reusable stainless steel TDT cans were used and the kinetic studies performed in a temperature range characteristic of thermal processing of low acid canned foods (110-125°C). The color parameter L was better described by a pseudo zero order while a pseudo first order reaction was found for 5-HMF a...

Optically induced structural phase transitions in ion Coulomb crystals

DEFF Research Database (Denmark)

Horak, Peter; Dantan, Aurelien Romain; Drewsen, Michael

2012-01-01

We investigate numerically the structural dynamics of ion Coulomb crystals confined in a three-dimensional harmonic trap when influenced by an additional one-dimensional optically induced periodical potential. We demonstrate that transitions between thermally excited crystal structures, such as b......We investigate numerically the structural dynamics of ion Coulomb crystals confined in a three-dimensional harmonic trap when influenced by an additional one-dimensional optically induced periodical potential. We demonstrate that transitions between thermally excited crystal structures...

Porous structure evolution of cellulose carbon fibres during heating in the initial activation stage

Energy Technology Data Exchange (ETDEWEB)

Babel, Krzysztof [Institute of Chemical Wood Technology, Agricultural Academy of Poznan, Ul. Wojska Polskiego 38/42, 60-637 Poznan (Poland)

2004-01-15

This paper is focused on the description of changes in the porous structure during fast heating to the activation temperature of the viscose fibres, pyrolysed to different final temperatures. Standard regenerated cellulose fibre structures were tested. Fabrics were subjected to pyrolysis, the samples being heated to final temperatures of 400, 600 and 850 C. Carbon fibres were subsequently heated to activation temperature (850 C) at a rate of 100 C/min, and then the samples were cooled down. The characteristics of obtained carbon preparations were examined. We have defined a level of restructuring and internal ordering of fibres which originated during slow pyrolysis as well as the range of temperature differences of pyrolysis and activation where fast increase of carbon fibre temperature before activation is advantageous for the development of porous structure. It allows for partial release of pores and fast rebuilding of structure accompanied by a considerable number of defects in the carbon matrix with higher reactivity to oxidiser which, in turn, promotes the development of pores in active carbon during oxidation. Temperature difference for viscose carbon fibres is approximately 150-300 C at pyrolysis temperature of 550-700 C.

Power density of piezoelectric transformers improved using a contact heat transfer structure.

Science.gov (United States)

Shao, Wei Wei; Chen, Li Juan; Pan, Cheng Liang; Liu, Yong Bin; Feng, Zhi Hua

2012-01-01

Based on contact heat transfer, a novel method to increase power density of piezoelectric transformers is proposed. A heat transfer structure is realized by directly attaching a dissipater to the piezoelectric transformer plate. By maintaining the vibration mode of the transformer and limiting additional energy losses from the contact interface, an appropriate design can improve power density of the transformer on a large scale, resulting from effective suppression of its working temperature rise. A prototype device was fabricated from a rectangular piezoelectric transformer, a copper heat transfer sheet, a thermal grease insulation pad, and an aluminum heat radiator. The experimental results show the transformer maintains a maximum power density of 135 W/cm(3) and an efficiency of 90.8% with a temperature rise of less than 10 °C after more than 36 h, without notable changes in performance. © 2012 IEEE

Heat Stress Nephropathy From Exercise-Induced Uric Acid Crystalluria: A Perspective on Mesoamerican Nephropathy.

Science.gov (United States)

Roncal-Jimenez, Carlos; García-Trabanino, Ramón; Barregard, Lars; Lanaspa, Miguel A; Wesseling, Catharina; Harra, Tamara; Aragón, Aurora; Grases, Felix; Jarquin, Emmanuel R; González, Marvin A; Weiss, Ilana; Glaser, Jason; Sánchez-Lozada, Laura G; Johnson, Richard J

2016-01-01

Mesoamerican nephropathy (MeN), an epidemic in Central America, is a chronic kidney disease of unknown cause. In this article, we argue that MeN may be a uric acid disorder. Individuals at risk for developing the disease are primarily male workers exposed to heat stress and physical exertion that predisposes to recurrent water and volume depletion, often accompanied by urinary concentration and acidification. Uric acid is generated during heat stress, in part consequent to nucleotide release from muscles. We hypothesize that working in the sugarcane fields may result in cyclic uricosuria in which uric acid concentrations exceed solubility, leading to the formation of dihydrate urate crystals and local injury. Consistent with this hypothesis, we present pilot data documenting the common presence of urate crystals in the urine of sugarcane workers from El Salvador. High end-of-workday urinary uric acid concentrations were common in a pilot study, particularly if urine pH was corrected to 7. Hyperuricemia may induce glomerular hypertension, whereas the increased urinary uric acid may directly injure renal tubules. Thus, MeN may result from exercise and heat stress associated with dehydration-induced hyperuricemia and uricosuria. Increased hydration with water and salt, urinary alkalinization, reduction in sugary beverage intake, and inhibitors of uric acid synthesis should be tested for disease prevention. Copyright © 2016 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.

Characteristics of entropy generation and heat transfer in double-layered micro heat sinks with complex structure

International Nuclear Information System (INIS)

Zhai, Y.L.; Xia, G.D.; Liu, X.F.; Wang, J.

2015-01-01

Highlights: • A novel DL-MCHS with complex structure is presented. • A model of entropy generation rate of DL-MCHSs is derived from the first and second laws of thermodynamics. • DL-MCHSs show better thermodynamic advantage and thermal performance under large volumetric flow rate. - Abstract: A new type of double-layered micro heat sink (DL-MCHS) with complex structure is designed and investigated numerically. Moreover, a model of entropy generation rate of DL-MCHSs is also derived from the first and second laws of thermodynamics. Results for the relationship of entropy generation rate between the first and second layer of DL-MCHSs, total entropy generation rate, the average temperature on the bottom wall, thermal resistance and pressure drop are investigated in detail, respectively. The results indicate that the effect of entropy generation rate of the first layer on total entropy generation rate is dominant. The thermal characteristic of DL-MCHSs with complex structure is better than that of all DL-MCHSs and single-layered micro heat sinks (SL-MCHSs) with simple structure under the same volumetric flow rate. However, DL-MCHSs only show better thermodynamic advantage and thermal performance than SL-MCHSs with complex structure when the volumetric flow rate larger than a certain value. It is not reasonable to use DL-MCHSs for cooling microelectronic equipments under small volumetric flow rate due to the larger irreversibility. Finally, the pressure drop of DL-MHCSs can be reduced by properly changing the channel height under various volumetric flow rates. Due to the less irreversibility and more uniform temperature distribution on the bottom wall, DL-MCHSs can effectively eliminate the internal thermal stresses in microelectronic equipments. Therefore, DL-MCHSs are an alternative method for the electronic cooling. Moreover, the thermodynamic analysis provides references for the actual application design

Structure and function of small heat shock/alpha-crystallin proteins: established concepts and emerging ideas.

Science.gov (United States)

MacRae, T H

2000-06-01

Small heat shock/alpha-crystallin proteins are defined by conserved sequence of approximately 90 amino acid residues, termed the alpha-crystallin domain, which is bounded by variable amino- and carboxy-terminal extensions. These proteins form oligomers, most of uncertain quaternary structure, and oligomerization is prerequisite to their function as molecular chaperones. Sequence modelling and physical analyses show that the secondary structure of small heat shock/alpha-crystallin proteins is predominately beta-pleated sheet. Crystallography, site-directed spin-labelling and yeast two-hybrid selection demonstrate regions of secondary structure within the alpha-crystallin domain that interact during oligomer assembly, a process also dependent on the amino terminus. Oligomers are dynamic, exhibiting subunit exchange and organizational plasticity, perhaps leading to functional diversity. Exposure of hydrophobic residues by structural modification facilitates chaperoning where denaturing proteins in the molten globule state associate with oligomers. The flexible carboxy-terminal extension contributes to chaperone activity by enhancing the solubility of small heat shock/alpha-crystallin proteins. Site-directed mutagenesis has yielded proteins where the effect of the change on structure and function depends upon the residue modified, the organism under study and the analytical techniques used. Most revealing, substitution of a conserved arginine residue within the alpha-crystallin domain has a major impact on quaternary structure and chaperone action probably through realignment of beta-sheets. These mutations are linked to inherited diseases. Oligomer size is regulated by a stress-responsive cascade including MAPKAP kinase 2/3 and p38. Phosphorylation of small heat shock/alpha-crystallin proteins has important consequences within stressed cells, especially for microfilaments.

Sensitization by wortmannin of heat- or X-ray induced cell death in cultured Chinese hamster V79 cells

International Nuclear Information System (INIS)

Tomita, Masanori; Suzuki, Norio; Matsumoto, Yoshihisa; Hirano, Kazuya; Umeda, Noriko; Sakai, Kazuo

2000-01-01

Here we found that wortmannin sensitized Chinese hamster V79 cells to hyperthermic treatment at 44.0 deg C as determined either by colony formation assay or by dye exclusion assay. Wortmannin enhanced heat-induced cell death accompanying cleavage of poly (ADP-ribose) polymerases (PARP). Additionally, the induction of heat shock protein HSP70 was suppressed and delayed in wortmannin-treated cells. Heat sensitizing effect of wortmannin was obvious at more than 5 or 10 μM of final concentrations, while radiosensitization was apparent at 5 μM. Requirement for high concentration of wortmannin, i.e., order of μM, suggests a possible role of certain protein kinases, such as DNA-PK and/or ATM among PI3-kinase family. The sensitization was minimal when wortmannin was added at the end of heat treatment. This was similar to the case of X-ray. Since heat-induced cell death and PARP cleavage preceded HSP70 induction phenomenon, the sensitization to the hyperthermic treatment was considered mainly caused by enhanced apoptotic cell death rather than secondary to suppression or delay by wortmannin of HSP70 induction. Further, in the present system radiosensitization by wortmannin was also at least partly mediated through enhancement of apoptotic cell death. (author)

Savannah River reactor process water heat exchanger tube structural integrity margin Task Number 92-005-1

International Nuclear Information System (INIS)

Mertz, G.E.; Barnes, D.M.; Sindelar, R.L.

1992-02-01

Twelve process water heat exchangers are designed to remove heat generated in the reactor tank. Each heat exchanger has approximately 9000, 1/2 inch diameter x 0.049 inches thick tubes. Minimum structural tubing requirements and the leak rate through postulated tubing defects are developed in this report A comparison of the structural requirements and the defect size calculated to produce leak rates of 0.5 lbs./day demonstrate adequate structural margins against gross tube rupture. Commercial nuclear experience with pressurized water reactor (PWR) steam generator plugging criteria are used for guidance in performing this analysis. It is important to note that the SRS reactors are low energy systems with normal operating pressures of 203 psig at 130 degree F while the PWR is a high energy system with operating pressures near 2200 psig at 600 degree F. Clearly the PVM steam generator has loadings which are more severe than the SRS heat exchangers. Consistent with the Regulatory Guide 1.121 criteria both wastage (wall thinning) and cracking are addressed. Structural limits on wall thinning and crack size are developed to preclude gross rupture. ASME Section XI criteria, with the factors of safety recommended by Regulatory Guide 1.121 are used to develop the allowable crack size criteria. Normal operating conditions (pressure, dead weight, and hydraulic drag) are considered with seismic and water hammer accident conditions. Both the wall thinning and crack size criteria are developed for the end-of-evaluation period. Allowances for corrosion, wear, or crack growth have not been included in this analysis Structurally, the tubing is over designed and can tolerate large defects with adequate margins against gross rupture. The structural margins of heat exchanger tubing are evident by contrasting the tubing's structural capacity, per the ASME Code, with its operating conditions/configuration

Heat transfer enhancement through control of added perturbation velocity in flow field

International Nuclear Information System (INIS)

Wang, Jiansheng; Wu, Cui; Li, Kangning

2013-01-01

Highlights: ► Three strategies which restrain the flow drag in heat transfer are proposed. ► Added perturbation induces quasi-streamwise vortices around controlled zone. ► The flow and heat transfer features depend on induced quasi-streamwise vortices. ► Vertical strategy has the best synthesis performance of three control strategies. ► Synthesis performance with control strategy is superior to that without strategy. - Abstract: The characteristics of heat transfer and flow, through an added perturbation velocity, in a rectangle channel, are investigated by Large Eddy Simulation (LES). The downstream, vertical, and upstream control strategy, which can suppress the lift of low speed streaks in the process of improving the performance of heat transfer, are adopted in numerical investigation. Taking both heat transfer and flow properties into consideration, the synthesis performance of heat transfer and flow of three control strategies are evaluated. The numerical results show that the flow structure in boundary layer has been varied obviously for the effect of perturbation velocity and induced quasi-streamwise vortices emerging around the controlled zone. The results indicate that the vertical control strategy has the best synthesis performance of the three control strategies, which also has the least skin frication coefficient. The upstream and downstream strategies can improve the heat transfer performance, but the skin frication coefficient is higher than that with vertical control strategy

Heat Flow Variation along the Nankai Trough Floor Correlated with the Structure of the Shikoku Basin Oceanic Crust

Science.gov (United States)

Yamano, M.; Kawada, Y.; Gao, X.

2016-12-01

Surface heat flow observed on the floor of the Nankai Trough, near the trench axis, is highly variable and does not well correspond to the seafloor age of the incoming Philippine Sea plate (Shikoku Basin). Recent detailed measurements between 133.5°E and 137°E revealed that heat flow on the trough floor significantly varies along the trough. The most conspicuous variation is found around 136°E. Heat flow is extremely high and variable between 135°E and 136°E, much higher than the value estimated from the age. On the east of 136°E, heat flow gradually decreases eastward over 50 km to the value nearly consistent with the age with no appreciable scatter. Elevated heat flow on the trough floor can be attributed to vigorous fluid circulation in a permeable layer (aquifer) in the subducted oceanic crust, which efficiently transports heat upward along the plate interface (Spinelli and Wang, 2008). The heat flow variation around 136°E may therefore arise from variation in the permeability structure of the crustal aquifer. A probable cause of the heterogeneity in the aquifer permeability is a structure boundary in the incoming Shikoku Basin, the boundary between the younger part on the west formed by spreading in NE-SW direction and the older part on the east formed by E-W spreading. It is located around 136°E, about the same place as the heat flow distribution boundary. A possible additional source of variation in the permeability structure is the geometry of the subducted Philippine Sea plate. A prominent bend in the subducted plate between 135°E and 136°E, which corresponds to the high heat flow area on the trough floor, may have fractured the oceanic crust and enhanced the aquifer permeability. We evaluated the influence of variations in the aquifer permeability on the thermal structure through 3D numerical modelling using a high thermal-conductivity proxy for heat transport by fluid flow. A sharp along-strike change in the permeability of the subducted

Structural steels for power generating equipment and heat and chemical heat treatments

International Nuclear Information System (INIS)

Astaf'ev, A.A.

1979-01-01

Development of structural steels for power generating equipment and for reactor engineering, in particular, is elucidated. Noted is utilization of the 15Kh2NMFA steels for the WWER-1000 reactor vessels, the 10GN2MFA steels for steam generators, pressurizers, vessels of the automatic emergency shut down and safety system; the 00Kh12N3DL steel for cast pump vessels and main locking bars. The recommendations on heat treatment of big forgings, for instance, ensuring the necessary complex of mechanical properties are given. Diffusion chromizing with subsequent nitriding of austenitic steels which increase durability of the components in BN reactors more than 4 times, is practised on a large scale

Integrated Thermal Protection Systems and Heat Resistant Structures

Science.gov (United States)

Pichon, Thierry; Lacoste, Marc; Glass, David E.

2006-01-01

In the early stages of NASA's Exploration Initiative, Snecma Propulsion Solide was funded under the Exploration Systems Research & Technology program to develop integrated thermal protection systems and heat resistant structures for reentry vehicles. Due to changes within NASA's Exploration Initiative, this task was cancelled early. This presentation provides an overview of the work that was accomplished prior to cancellation. The Snecma team chose an Apollo-type capsule as the reference vehicle for the work. They began with the design of a ceramic aft heatshield (CAS) utilizing C/SiC panels as the capsule heatshield, a C/SiC deployable decelerator and several ablators. They additionally developed a health monitoring system, high temperature structures testing, and the insulation characterization. Though the task was pre-maturely cancelled, a significant quantity of work was accomplished.

Heat capacity jumps induced by magnetic field in the Er{sub 2}HoAl{sub 5}O{sub 12} garnet

Energy Technology Data Exchange (ETDEWEB)

Shevchenko, E.V. [Centre for Diagnostics of Functional Materials for Medicine, Pharmacology and Nanoelectronics, St. Petersburg State University, St. Petersburg, 198504 (Russian Federation); Charnaya, E.V., E-mail: charnaya@live.com [Physics Department, St. Petersburg State University, St. Petersburg, 198504 (Russian Federation); Lee, M.K. [Department of Physics, National Cheng Kung University, Tainan, 70101 Taiwan (China); NSC Instrument Center at NCKU, Tainan, 70101 Taiwan (China); Chang, L.J. [Department of Physics, National Cheng Kung University, Tainan, 70101 Taiwan (China); Khazanov, E.N.; Taranov, A.V. [Kotel' nikov Institute of Radio Engineering and Electronics RAS, 125009 (Russian Federation); Bugaev, A.S. [Moscow Institute of Physics and Technology, Moscow, 141700 (Russian Federation)

2017-01-30

Measurements of the heat capacity were carried out for the mixed Er{sub 2}HoAl{sub 5}O{sub 12} garnet at magnetic fields up to 15 T. The heat capacity variations at low temperatures were dominated by the Schottky anomalies. In addition, anomalous sharp steps in the heat capacity were observed in magnetic fields stronger than 8 T upon cooling as well as upon warming. The temperatures of the steps increased with increasing magnetic field. Jumps found upon cooling and warming were shifted relative to each other showing the thermal hysteresis. The sharp decrease in the heat capacity at low temperatures suggested the blocking of magnetic flips induced by strong enough magnetic fields. - Highlights: • Anomalous steps of the heat capacity were observed in the Er{sub 2}HoAl{sub 5}O{sub 12} garnet. • The steps are induced by magnetic field at low temperatures. • The temperatures of the steps increased with increasing magnetic field. • The steps show a pronounced thermal hysteresis. • The findings suggest the blocking of the magnetic moment flips at field.

The Vibration Analysis of Tube Bundles Induced by Fluid Elastic Excitation in Shell Side of Heat Exchanger

Science.gov (United States)

Bao, Minle; Wang, Lu; Li, Wenyao; Gao, Tianze

2017-09-01

Fluid elastic excitation in shell side of heat exchanger was deduced theoretically in this paper. Model foundation was completed by using Pro / Engineer software. The finite element model was constructed and imported into the FLUENT module. The flow field simulation adopted the dynamic mesh model, RNG k-ε model and no-slip boundary conditions. Analysing different positions vibration of tube bundles by selecting three regions in shell side of heat exchanger. The results show that heat exchanger tube bundles at the inlet of the shell side are more likely to be failure due to fluid induced vibration.

Evaluation of induced activity, decay heat and dose rate distribution after shutdown in ITER

Energy Technology Data Exchange (ETDEWEB)

Maki, Koichi [Hitachi Ltd., Ibaraki (Japan). Hitachi Research Lab.; Satoh, Satoshi; Hayashi, Katsumi; Yamada, Koubun; Takatsu, Hideyuki; Iida, Hiromasa

1997-03-01

Induced activity, decay heat and dose rate distributions after shutdown were estimated for 1MWa/m{sup 2} operation in ITER. The activity in the inboard blanket one day after shutdown is 1.5x10{sup 11}Bq/cm{sup 3}, and the average decay heating rate 0.01w/cm{sup 3}. The dose rate outside the 120cm thick concrete biological shield is two order higher than the design criterion of 5{mu}Sv/h. This indicates that the biological shield thickness should be enhanced by 50cm in concrete, that is, total thickness 170cm for workers to enter the reactor room and to perform maintenance. (author)

Heat insulating structure for use in transporting and handling gas of high temperature and pressure

International Nuclear Information System (INIS)

Mathusima, T.; Sato, T.; Uenishi, A.

1980-01-01

A heat insulating structure is described that has a heat-resistant tube disposed in a tubular cylindrical body and defining a passage for a high temperature gas, a heat insulating material disposed between the tube and the tubular cylindrical body and adapted to prevent the heat possessed by the gas from being transmitted to the tubular cylindrical body, and a spring adapted to bias the heat insulating material toward the inner surface of the tubular cylindrical body, so as to prevent the formation of a bypass passage for the gas including the gap between the tubular cylindrical body and the heat insulating material. The heat insulating material consists of a plurality of fibrous heat insulating materials mainly consisting of bulky fibrous materials and a plurality of shaped fibrous heat insulating materials. These fibrous heat insulating materials and the shaped fibrous heat insulating materials are arranged alternatingly and independently in the axial direction. In each of the bulky fibrous heat insulating material, disposed is a spring for biasing the shaped fibrous heat insulating material in the axial direction

Heat defense control in an experimental heat disorder

Science.gov (United States)

Romanovsky, A. A.; Blatteis, C. M.

Both whole-body heat exposure and intraperitoneal heating (IPH) result in a body temperature (Tb) fall that occurs once heating is abated (''hyperthermia- induced hypothermia''). This phenomenon involves a decrease in the threshold Tb (Tb-thresh) for activation of metabolic heat production (cold defense). Whether the Tb-thresh for ear skin vasodilation (heat defense) also changes during hyperthermia-induced hypothermia remains unknown. In experiment 1, we applied IPH to guinea pigs by perfusing water through a preimplanted intraperitoneal thermode and delivered the total heat load of either approximately 1.5 kJ (''short'' IPH; perfusion duration: 14 min) or approximately 3.0 kJ (''long'' IPH; 40 min). Short IPH caused skin vasodilation and a 1.1°C rise in Tb; no hypothermia occurred when IPH ceased. Long IPH caused vasodilation and hyperthermia of a comparable magnitude (1.4°C) that were followed by a Tb fall to 1.9°C below the preheating value. In experiment 2, the Tb-thresh for skin vasodilation was measured twice: at the beginning of long IPH and at the nadir of the post-IPH hypothermia. The two Tb-thresh values were 39.0 (SEM 0.1)°C and 39.2 (SEM 0.2)°C respectively. In the controls, the Tb-thresh was measured at the beginning and after short IPH; both control values were 39.0 (SEM 0.2)°C. We conclude that the hyperthermia- induced hypothermia, although previously shown to be coupled with a decrease in the Tb-thresh for cold defense, occurs without any substantial change in the Tb-thresh for heat defense. We speculate that postheating thermoregulatory disorders are associated with threshold dissociation, thus representing the poikilothermic (wide dead-band) type of Tb control.

Theoretical potential for low energy consumption phase change memory utilizing electrostatically-induced structural phase transitions in 2D materials

Science.gov (United States)

Rehn, Daniel A.; Li, Yao; Pop, Eric; Reed, Evan J.

2018-01-01

Structural phase-change materials are of great importance for applications in information storage devices. Thermally driven structural phase transitions are employed in phase-change memory to achieve lower programming voltages and potentially lower energy consumption than mainstream nonvolatile memory technologies. However, the waste heat generated by such thermal mechanisms is often not optimized, and could present a limiting factor to widespread use. The potential for electrostatically driven structural phase transitions has recently been predicted and subsequently reported in some two-dimensional materials, providing an athermal mechanism to dynamically control properties of these materials in a nonvolatile fashion while achieving potentially lower energy consumption. In this work, we employ DFT-based calculations to make theoretical comparisons of the energy required to drive electrostatically-induced and thermally-induced phase transitions. Determining theoretical limits in monolayer MoTe2 and thin films of Ge2Sb2Te5, we find that the energy consumption per unit volume of the electrostatically driven phase transition in monolayer MoTe2 at room temperature is 9% of the adiabatic lower limit of the thermally driven phase transition in Ge2Sb2Te5. Furthermore, experimentally reported phase change energy consumption of Ge2Sb2Te5 is 100-10,000 times larger than the adiabatic lower limit due to waste heat flow out of the material, leaving the possibility for energy consumption in monolayer MoTe2-based devices to be orders of magnitude smaller than Ge2Sb2Te5-based devices.

Promotion of Pt-Ru/C catalysts driven by heat treated induced surface segregation for methanol oxidation reaction

International Nuclear Information System (INIS)

Wei Yuchen; Liu Chenwei; Chang Weijung; Wang Kuanwen

2011-01-01

Research highlights: → Thermal treatments on the Pt-Ru/C induce different extents of surface segregation. → O 2 treatment results in obvious Ru segregation and formation of RuO 2 . → Catalysts treated in H 2 have the excellent CO de-poisoning ability. → N 2 treatment suppresses the surface Pt depletion and hence promotes the MOR. - Abstract: Carbon supported Pt-Ru/C (1:1) alloy catalysts supplied by E-TEK are widely used for fuel cell research. Heat treatments in various atmospheres are conducted for the promotion of the methanol oxidation reaction (MOR) and the investigation of the structure-activity relationship (SAR) of the catalysts. The alloy structures, surface compositions, surface species, and electro-catalytic activities of the alloy catalysts are characterized by X-ray diffraction (XRD), temperature-programmed reduction (TPR), X-ray photoelectron spectroscopy (XPS), and cyclic voltammetry (CV), respectively. The as-received Pt-Ru/C catalysts have a Ru rich in the inner core and Pt rich on the outer shell structure. Thermal treatments on the catalysts induce Ru surface segregation in different extents and thereby lead to their alteration of the alloying degrees. O 2 treatment results in obvious Ru segregation and formation of RuO 2 . Catalysts treated in H 2 have the highest I f /I b value in the CV scans among all samples, indicating the catalysts have the excellent CO de-poisoning ability as evidenced by anodic CO stripping experiments. N 2 treatment may serve as an adjustment process for the surface composition and structure of the catalysts, which can suppress the surface Pt depletion (∼60% Pt on the surface), make the components stable and hence promote the MOR significantly.

Promotion of Pt-Ru/C catalysts driven by heat treated induced surface segregation for methanol oxidation reaction

Energy Technology Data Exchange (ETDEWEB)

Wei Yuchen; Liu Chenwei; Chang Weijung [Institute of Materials Science and Engineering, National Central University, Taoyuan 32001, Taiwan (China); Wang Kuanwen, E-mail: kuanwen.wang@gmail.com [Institute of Materials Science and Engineering, National Central University, Taoyuan 32001, Taiwan (China)

2011-01-12

Research highlights: > Thermal treatments on the Pt-Ru/C induce different extents of surface segregation. > O{sub 2} treatment results in obvious Ru segregation and formation of RuO{sub 2}. > Catalysts treated in H{sub 2} have the excellent CO de-poisoning ability. > N{sub 2} treatment suppresses the surface Pt depletion and hence promotes the MOR. - Abstract: Carbon supported Pt-Ru/C (1:1) alloy catalysts supplied by E-TEK are widely used for fuel cell research. Heat treatments in various atmospheres are conducted for the promotion of the methanol oxidation reaction (MOR) and the investigation of the structure-activity relationship (SAR) of the catalysts. The alloy structures, surface compositions, surface species, and electro-catalytic activities of the alloy catalysts are characterized by X-ray diffraction (XRD), temperature-programmed reduction (TPR), X-ray photoelectron spectroscopy (XPS), and cyclic voltammetry (CV), respectively. The as-received Pt-Ru/C catalysts have a Ru rich in the inner core and Pt rich on the outer shell structure. Thermal treatments on the catalysts induce Ru surface segregation in different extents and thereby lead to their alteration of the alloying degrees. O{sub 2} treatment results in obvious Ru segregation and formation of RuO{sub 2}. Catalysts treated in H{sub 2} have the highest I{sub f}/I{sub b} value in the CV scans among all samples, indicating the catalysts have the excellent CO de-poisoning ability as evidenced by anodic CO stripping experiments. N{sub 2} treatment may serve as an adjustment process for the surface composition and structure of the catalysts, which can suppress the surface Pt depletion ({approx}60% Pt on the surface), make the components stable and hence promote the MOR significantly.

Structural analysis of equilibrium and ohmic heating coil assemblies for the TFTR

International Nuclear Information System (INIS)

Chattopadhyay, S.

1975-10-01

The structural adequacy of the equilibrium and ohmic heating coils and their support systems for the TFTR device has been investigated. The capability of the coils to span ribs of the support structure has been established. The support structure has been found to be effective in resisting the magnetic forces in the coils. The bands encircling the outboard coils and the band tensioning devices have been found to perform adequately. The analysis is based on October 1975 conceptual design

Metal-insulator transition upon heating and negative-differential-resistive-switching induced by self-heating in BaCo0.9Ni0.1S1.8

International Nuclear Information System (INIS)

Fisher, B.; Genossar, J.; Chashka, K. B.; Patlagan, L.; Reisner, G. M.

2014-01-01

The layered compound BaCo 1−x Ni x S 2−y (0.05  1−x Ni x S 2−y (nominal x = 0.1 and y = 0.2). These were due to the steep metal to insulator transition upon heating followed by the activated behavior of the resistivity above the transition. The major role of Joule heating in switching is supported by the absence of nonlinearity in the current as function of voltage, I(V), obtained in pulsed measurements, in the range of electric fields relevant to d.c. measurements. The voltage-controlled negative differential resistance around the threshold for switching was explained by a simple model of self-heating. The main difficulty in modeling I(V) from the samples resistance as function of temperature R(T) was the progressive increase of R(T), and to a lesser extend the decrease of the resistance jumps at the transitions, caused by the damage induced by cycling through the transitions by heating or self-heating. This was dealt with by following systematically R(T) over many cycles and by using the data of R(T) in the heating cycle closest to that of the self-heating one

Numerical analysis of high-power broad-area laser diode with improved heat sinking structure using epitaxial liftoff technique

Science.gov (United States)

Kim, Younghyun; Sung, Yunsu; Yang, Jung-Tack; Choi, Woo-Young

2018-02-01

The characteristics of high-power broad-area laser diodes with the improved heat sinking structure are numerically analyzed by a technology computer-aided design based self-consistent electro-thermal-optical simulation. The high-power laser diodes consist of a separate confinement heterostructure of a compressively strained InGaAsP quantum well and GaInP optical cavity layers, and a 100-μm-wide rib and a 2000-μm long cavity. In order to overcome the performance deteriorations of high-power laser diodes caused by self-heating such as thermal rollover and thermal blooming, we propose the high-power broad-area laser diode with improved heat-sinking structure, which another effective heat-sinking path toward the substrate side is added by removing a bulk substrate. It is possible to obtain by removing a 400-μm-thick GaAs substrate with an AlAs sacrificial layer utilizing well-known epitaxial liftoff techniques. In this study, we present the performance improvement of the high-power laser diode with the heat-sinking structure by suppressing thermal effects. It is found that the lateral far-field angle as well as quantum well temperature is expected to be improved by the proposed heat-sinking structure which is required for high beam quality and optical output power, respectively.

Diagnostics of materials and structures of heating system as a component of ecological management in a modern city

Directory of Open Access Journals (Sweden)

Verstina Natalia

2016-01-01

Full Text Available The maintenance of materials and structures of the underground space in modern cities which contains many engineering structures is considered in the article. It is claimed on the example of quantitative data that the underground structures exert a great influence on the ecological situation of the city. The matters of the research included the analysis of the main heating systems as the most responsible city structure; the conclusions obtained can be also used for smaller heat pipelines. The article includes the comparisons of modern technical methods of diagnostics of materials and heating systems structures according to the results of experiment, as well as the characteristic of norms of control of the materials condition at the stages of construction and maintenance applied in the developed countries. On this basis, the author has developed and presented a system of diagnostics taking into account the alternation of measures during the heating period as well as the season when heat supply is not required. For an effective ecological management in modern cities, it is suggested to create the automated data base of materials and structures of the heating systems on the basis of the developed scheme of their conditions and events, which needs to be used for forecasting of environmental risks and planning of recovery works with consideration of special features of the maintenance processes. The direction of the further research is defined: it is the expansion of the stated approaches on other types of underground communications in modern cities.

Extremely low-frequency magnetic fields can impair spermatogenesis recovery after reversible testicular damage induced by heat.

Science.gov (United States)

Tenorio, Bruno Mendes; Ferreira Filho, Moisés Bonifacio Alves; Jimenez, George Chaves; de Morais, Rosana Nogueira; Peixoto, Christina Alves; Nogueira, Romildo de Albuquerque; da Silva Junior, Valdemiro Amaro

2014-06-01

Male infertility is often related to reproductive age couples experiencing fertility-related issues. Men may have fertility problems associated with reversible testicular damage. Considering that men have been increasingly exposed to extremely low-frequency magnetic fields generated by the production, distribution and use of electricity, this study analyzed whether 60 Hz and 1 mT magnetic field exposure may impair spermatogenesis recovery after reversible testicular damage induced by heat shock using rats as an experimental model. Adult male rats were subjected to a single testicular heat shock (HS, 43 °C for 12 min) and then exposed to the magnetic field for 15, 30 and 60 d after HS. Magnetic field exposure during the spermatogenesis recovery induced changes in testis components volume, cell ultrastructure and histomorphometrical parameters. Control animals had a reestablished and active spermatogenesis at 60 d after heat shock, while animals exposed to magnetic field still showed extensive testicular degeneration. Magnetic field exposure did not change the plasma testosterone. In conclusion, extremely low-frequency magnetic field may be harmful to fertility recovery in males affected by reversible testicular damage.

Analysis of the beam induced heat loads on the LHC arc beam screens during Run 2

CERN Document Server

Iadarola, Giovanni; Dijkstal, Philipp; Mether, Lotta; CERN. Geneva. ATS Department

2017-01-01

During Run 2 the Large Hadron Collider (LHC) has been routinely operated with 25 ns bunch spacing. In these conditions large heat loads have been measured on the beam screens of the superconducting magnets, together with other observations indicating that an electron cloud develops in the beam chambers. The analysis of these heat loads has revealed several interesting features allowing to pinpoint peculiar characteristics of the observed beam-induced heating. This document describes the main findings of this analysis including the evolution taking place during the run, the observed dependence on the beam conditions and the results from special tests and dedicated instrumentation. The differences observed in the behavior of the eight LHC arcs are also discussed.

Thermally-Induced Structural Disturbances of Rigid Panel Solar Arrays

Science.gov (United States)

Johnston, John D.; Thornton, Earl A.

1997-01-01

The performance of a significant number of spacecraft has been impacted negatively by attitude disturbances resulting from thermally-induced motions of flexible structures. Recent examples of spacecraft affected by these disturbances include the Hubble Space Telescope (HST) and the Upper Atmosphere Research Satellite (UARS). Thermally-induced structural disturbances occur as the result of rapid changes in thermal loading typically initiated as a satellite exits or enters the Earth's shadow. Temperature differences in flexible appendages give rise to structural deformations, which in turn result in disturbance torques reacting back on the spacecraft. Structures which have proven susceptible to these disturbances include deployable booms and solar arrays. This paper investigates disturbances resulting from thermally-induced deformations of rigid panel solar arrays. An analytical model for the thermal-structural response of the solar array and the corresponding disturbance torque are presented. The effect of these disturbances on the attitude dynamics of a simple spacecraft is then investigated using a coupled system of governing equations which includes the effects of thermally-induced deformations. Numerical results demonstrate the effect of varying solar array geometry on the dynamic response of the system.

Review of the experience obtained in the evaluation of vibrations and their effects on the structural integrity of heat exchangers

International Nuclear Information System (INIS)

Ghiselli, Alberto M.; Pastorini, Alberto; Kulichevsky Raul

2000-01-01

Flow induced vibrations may produce damage of shell-tube type heat exchangers, condensers and steam generators tubes. These vibrations could be produce by changes in the equipment operational condition or by a wrong evaluation during the design procedure. The typical results are tube damage by impact or fretting wear. This paper include a review of the flow-induced vibration mechanisms that affect shell-tube heat exchangers and some practical examples that show the results obtained evaluating this equipment. (author)

Theory of hysteresis during electron heating of electromagnetic wave scattering by self-organized dust structures in complex plasmas

Energy Technology Data Exchange (ETDEWEB)

Tsytovich, Vadim, E-mail: tsytov@lpi.ru [A. M. Prokhorov General Physics Institute, Russian Academy of Sciences, Vavilova str. 38, Moscow 119991 (Russian Federation); Max Planck Institute for Extraterrestrial Physics, Garching (Germany); Gusein-zade, Namik; Ignatov, Alexander [A. M. Prokhorov General Physics Institute, Russian Academy of Sciences, Vavilova str. 38, Moscow 119991 (Russian Federation); Medicobiologic Faculty, Pirogov Russian National Research Medical University, Moscow (Russian Federation)

2015-07-15

Dust structuring is a natural and universal process in complex plasmas. The scattering of electromagnetic waves by dust structures is governed by the factor of coherency, i.e., the total number of coherent electrons in a single structure. In the present paper, we consider how the factor of coherency changes due to additional pulse electron heating and show that it obeys a hysteresis. After the end of the pulse heating, the scattering intensity differs substantially from that before heating. There are three necessary conditions for scattering hysteresis: first, the radiation wavelength should be larger than the pattern (structure) size; second, the total number of coherent electrons confined by the structure should be large; and third, the heating pulse duration should be shorter than the characteristic time of dust structure formation. We present the results of numerical calculations using existing models of self-consistent dust structures with either positively or negatively charged dust grains. It is shown that, depending on the grain charge and the ionization rate, two types of hysteresis are possible: one with a final increase of the scattering and the other with a final decrease of the scattering. It is suggested that the hysteresis of coherent scattering can be used as a tool in laboratory experiments and that it can be a basic mechanism explaining the observed hysteresis in radar scattering by noctilucent clouds during active experiments on electron heating in mesosphere.

Multilinear Model of Heat Exchanger with Hammerstein Structure

Directory of Open Access Journals (Sweden)

Dragan Pršić

2016-01-01

Full Text Available The multilinear model control design approach is based on the approximation of the nonlinear model of the system by a set of linear models. The paper presents the method of creation of a bank of linear models of the two-pass shell and tube heat exchanger. The nonlinear model is assumed to have a Hammerstein structure. The set of linear models is formed by decomposition of the nonlinear steady-state characteristic by using the modified Included Angle Dividing method. Two modifications of this method are proposed. The first one refers to the addition to the algorithm for decomposition, which reduces the number of linear segments. The second one refers to determination of the threshold value. The dependence between decomposition of the nonlinear characteristic and the linear dynamics of the closed-loop system is established. The decoupling process is more formal and it can be easily implemented by using software tools. Due to its simplicity, the method is particularly suitable in complex systems, such as heat exchanger networks.

Effect of heat-induced pain stimuli on pulse transit time and pulse wave amplitude in healthy volunteers.

Science.gov (United States)

van Velzen, Marit H N; Loeve, Arjo J; Kortekaas, Minke C; Niehof, Sjoerd P; Mik, Egbert G; Stolker, Robert J

2016-01-01

Pain is commonly assessed subjectively by interpretations of patient behaviour and/or reports from patients. When this is impossible the availability of a quantitative objective pain assessment tool based on objective physiological parameters would greatly benefit clinical practice and research beside the standard self-report tests. Vasoconstriction is one of the physiological responses to pain. The aim of this study was to investigate whether pulse transit time (PTT) and pulse wave amplitude (PWA) decrease in response to this vasoconstriction when caused by heat-induced pain. The PTT and PWA were measured in healthy volunteers, on both index fingers using photoplethysmography and electrocardiography. Each subject received 3 heat-induced pain stimuli using a Temperature-Sensory Analyzer thermode block to apply a controlled, increasing temperature from 32.0 °C to 50.0 °C to the skin. After reaching 50.0 °C, the thermode was immediately cooled down to 32.0 °C. The study population was divided into 2 groups with a time-interval between the stimuli 20s or 60s. The results showed a significant (p  Heat-induced pain causes a decrease of PTT and PWA. Consequently, it is expected that, in the future, PTT and PWA may be applied as objective indicators of pain, either beside the standard self-report test, or when self-report testing is impossible.

Flow-induced structure in colloidal suspensions

Energy Technology Data Exchange (ETDEWEB)

Vermant, J [Department of Chemical Engineering, K U Leuven, W de Croylaan 46, B-3001 Leuven (Belgium); Solomon, M J [Department of Chemical Engineering, University of Michigan, Ann Arbor, MI 48109-2136 (United States)

2005-02-02

We review the sequences of structural states that can be induced in colloidal suspensions by the application of flow. Structure formation during flow is strongly affected by the delicate balance among interparticle forces, Brownian motion and hydrodynamic interactions. The resulting non-equilibrium microstructure is in turn a principal determinant of the suspension rheology. Colloidal suspensions with near hard-sphere interactions develop an anisotropic, amorphous structure at low dimensionless shear rates. At high rates, clustering due to strong hydrodynamic forces leads to shear thickening rheology. Application of steady-shear flow to suspensions with repulsive interactions induces a rich sequence of transitions to one-, two-and three-dimensional order. Oscillatory-shear flow generates metastable ordering in suspensions with equilibrium liquid structure. On the other hand, short-range attractive interactions can lead to a fluid-to-gel transition under quiescent suspensions. Application of flow leads to orientation, breakup, densification and spatial reorganization of aggregates. Using a non-Newtonian suspending medium leads to additional possibilities for organization. We examine the extent to which theory and simulation have yielded mechanistic understanding of the microstructural transitions that have been observed. (topical review)

A Study on the Structural Integrity Considering the Installation of a Micro-tube Heat Exchanger

Energy Technology Data Exchange (ETDEWEB)

Oh, Se Yun; Kim, Tae Jin; Cho, Jong Rae [Korea Maritime and Ocean University, Busan (Korea, Republic of); Jeong, Ho Sung [Pusan National University, Busan (Korea, Republic of)

2015-04-15

The objective of this study is to predict the structural characteristics of a heat exchanger mounted on an aircraft engine using finite element analysis. The plastic fracture and life of the heat exchanger were estimated by a thermo-mechanical analysis. Tensile tests were conducted under high temperature conditions (700, 800, 900, 1000 K) using five specimens to obtain the mechanical properties of the Inconel 625 tubes. To assess the structural characteristics of the heat exchanger, the full and partial models were applied under the operating conditions given by the thermo-mechanical and inertial load. As a result, the case, tubesheet, flange, and mounting components have a reasonable safety margin to the allowable stress assuming a fatigue strength of Inconel 625 of 10000 cycles under 1000 K.

A Study on the Structural Integrity Considering the Installation of a Micro-tube Heat Exchanger

International Nuclear Information System (INIS)

Oh, Se Yun; Kim, Tae Jin; Cho, Jong Rae; Jeong, Ho Sung

2015-01-01

The objective of this study is to predict the structural characteristics of a heat exchanger mounted on an aircraft engine using finite element analysis. The plastic fracture and life of the heat exchanger were estimated by a thermo-mechanical analysis. Tensile tests were conducted under high temperature conditions (700, 800, 900, 1000 K) using five specimens to obtain the mechanical properties of the Inconel 625 tubes. To assess the structural characteristics of the heat exchanger, the full and partial models were applied under the operating conditions given by the thermo-mechanical and inertial load. As a result, the case, tubesheet, flange, and mounting components have a reasonable safety margin to the allowable stress assuming a fatigue strength of Inconel 625 of 10000 cycles under 1000 K

3D numerical modeling of coupled phenomena in induced processes of heat treatment with malice

Directory of Open Access Journals (Sweden)

Triwong Peeteenut

2008-01-01

Full Text Available This paper describes a multi-method Malice package for three dimension coupled phenomena in induced processes of heat treatment by an algorithm weakly coupled with the Migen package integral method defining the electromagnetic model and the Flux-Expert package finite element method defining the thermal model. The integral method is well suited to inductive systems undergoing sinusoidal excitation at midrange or high frequency. The unknowns of both models are current density, scalar potential and temperature. Joule power in the electromagnetic model is generated by Eddy currents. It becomes the heat source in the thermal model.

Investigation of the radiation properties of magnetospheric ELF waves induced by modulated ionospheric heating

Science.gov (United States)

Wang, Feng; Ni, Binbin; Zhao, Zhengyu; Zhao, Shufan; Zhao, Guangxin; Wang, Min

2017-05-01

Electromagnetic extremely low frequency (ELF) waves play an important role in modulating the Earth's radiation belt electron dynamics. High-frequency (HF) modulated heating of the ionosphere acts as a viable means to generate artificial ELF waves. The artificial ELF waves can reside in two different plasma regions in geo-space by propagating in the ionosphere and penetrating into the magnetosphere. As a consequence, the entire trajectory of ELF wave propagation should be considered to carefully analyze the wave radiation properties resulting from modulated ionospheric heating. We adopt a model of full wave solution to evaluate the Poynting vector of the ELF radiation field in the ionosphere, which can reflect the propagation characteristics of the radiated ELF waves along the background magnetic field and provide the initial condition of waves for ray tracing in the magnetosphere. The results indicate that the induced ELF wave energy forms a collimated beam and the center of the ELF radiation shifts obviously with respect to the ambient magnetic field with the radiation power inversely proportional to the wave frequency. The intensity of ELF wave radiation also shows a weak correlation with the size of the radiation source or its geographical location. Furthermore, the combination of ELF propagation in the ionosphere and magnetosphere is proposed on basis of the characteristics of the ELF radiation field from the upper ionospheric boundary and ray tracing simulations are implemented to reasonably calculate magnetospheric ray paths of ELF waves induced by modulated ionospheric heating.

Whole-body fluid distribution in humans during dehydration and recovery, before and after humid-heat acclimation induced using controlled hyperthermia.

Science.gov (United States)

Patterson, M J; Stocks, J M; Taylor, N A S

2014-04-01

This experiment was designed to test the hypothesis that the plasma volume is not selectively defended during exercise- and heat-induced dehydration following humid-heat acclimation. Eight physically active males were heat acclimated (39.8 °C, relative humidity 59.2%) using 17 days of controlled hyperthermia (core temperature: 38.5 °C). Inter-compartmental fluid losses and movements were tracked (radioisotopes and Evans blue dye) during progressive dehydration (cycling) in these same conditions and also during a resting recovery without fluid replacement (28 °C), before (day 1), during (day 8) and after heat acclimation (day 22). On days 8 and 22, there were significant increases in total body water, interstitial fluid and plasma volume (P 0.05). The baseline plasma volume remained expanded throughout: 43.4 [±2.6 (day 1)], 49.1 [±2.4 (day 8); P recovery, plasma volume restoration commenced, with the intracellular fluid contribution becoming more pronounced as acclimation progressed. It is concluded that the plasma volume was not defended more vigorously following humid-heat acclimation. Indeed, a greater fluid loss may well underlie the mechanisms for enhancing plasma volume recovery when heat acclimation is induced using the controlled-hyperthermia technique. © 2013 Scandinavian Physiological Society. Published by John Wiley & Sons Ltd.

An alternatively spliced heat shock transcription factor, OsHSFA2dI, functions in the heat stress-induced unfolded protein response in rice.

Science.gov (United States)

Cheng, Q; Zhou, Y; Liu, Z; Zhang, L; Song, G; Guo, Z; Wang, W; Qu, X; Zhu, Y; Yang, D

2015-03-01

As sessile organisms, plants have evolved a wide range of defence pathways to cope with environmental stress such as heat shock. However, the molecular mechanism of these defence pathways remains unclear in rice. In this study, we found that OsHSFA2d, a heat shock transcriptional factor, encodes two main splice variant proteins, OsHSFA2dI and OsHSFA2dII in rice. Under normal conditions, OsHSFA2dII is the dominant but transcriptionally inactive spliced form. However, when the plant suffers heat stress, OsHSFA2d is alternatively spliced into a transcriptionally active form, OsHSFA2dI, which participates in the heat stress response (HSR). Further study found that this alternative splicing was induced by heat shock rather than photoperiod. We found that OsHSFA2dI is localised to the nucleus, whereas OsHSFA2dII is localised to the nucleus and cytoplasm. Moreover, expression of the unfolded protein response (UNFOLDED PROTEIN RESPONSE) sensors, OsIRE1, OsbZIP39/OsbZIP60 and the UNFOLDED PROTEIN RESPONSE marker OsBiP1, was up-regulated. Interestingly, OsbZIP50 was also alternatively spliced under heat stress, indicating that UNFOLDED PROTEIN RESPONSE signalling pathways were activated by heat stress to re-establish cellular protein homeostasis. We further demonstrated that OsHSFA2dI participated in the unfolded protein response by regulating expression of OsBiP1. © 2014 German Botanical Society and The Royal Botanical Society of the Netherlands.

The use of segregated heat sink structures to achieve enhanced passive cooling for outdoor wireless devices

International Nuclear Information System (INIS)

O'Flaherty, K; Punch, J

2014-01-01

Environmental standards which govern outdoor wireless equipment can stipulate stringent conditions: high solar loads (up to 1 kW/m 2 ), ambient temperatures as high as 55°C and negligible wind speeds (0 m/s). These challenges result in restrictions on power dissipation within a given envelope, due to the limited heat transfer rates achievable with passive cooling. This paper addresses an outdoor wireless device which features two segregated heat sink structures arranged vertically within a shielded chimney structure: a primary sink to cool temperature-sensitive components; and a secondary sink for high power devices. Enhanced convective cooling of the primary sink is achieved due to the increased mass flow within the chimney generated by the secondary sink. An unshielded heat sink was examined numerically, theoretically and experimentally, to verify the applicability of the methods employed. Nusselt numbers were compared for three cases: an unshielded heat sink; a sink located at the inlet of a shield; and a primary heat sink in a segregated structure. The heat sink, when placed at the inlet of a shield three times the length of the sink, augmented the Nusselt number by an average of 64% compared to the unshielded case. The Nusselt number of the primary was found to increase proportionally with the temperature of the secondary sink, and the optimum vertical spacing between the primary and secondary sinks was found to be close to zero, provided that conductive transfer between the sinks was suppressed.

Radiation induced nano structures

International Nuclear Information System (INIS)

Ibragimova, E.M.; Kalanov, M.U.; Khakimov, Z.

2006-01-01

Full text: Nanometer-size silicon clusters have been attracting much attention due to their technological importance, in particular, as promising building blocks for nano electronic and nano photonic systems. Particularly, silicon wires are of great of interest since they have potential for use in one-dimensional quantum wire high-speed field effect transistors and light-emitting devices with extremely low power consumption. Carbon and metal nano structures are studied very intensely due to wide possible applications. Radiation material sciences have been dealing with sub-micron objects for a long time. Under interaction of high energy particles and ionizing radiation with solids by elastic and inelastic mechanisms, at first point defects are created, then they form clusters, column defects, disordered regions (amorphous colloids) and finally precipitates of another crystal phase in the matrix. Such irradiation induced evolution of structure defects and phase transformations was observed by X-diffraction techniques in dielectric crystals of quartz and corundum, which exist in and crystal modifications. If there is no polymorphism, like in alkali halide crystals, then due to radiolysis halogen atoms are evaporated from the surface that results in non-stoichiometry or accumulated in the pores formed by metal vacancies in the sub-surface layer. Nano-pores are created by intensive high energy particles irradiation at first chaotically and then they are ordered and in part filled by inert gas. It is well-known mechanism of radiation induced swelling and embrittlement of metals and alloys, which is undesirable for construction materials for nuclear reactors. Possible solution of this problem may come from nano-structured materials, where there is neither swelling nor embrittlement at gas absorption due to very low density of the structure, while strength keeps high. This review considers experimental observations of radiation induced nano-inclusions in insulating

A global overview of drought and heat-induced tree mortality reveals emerging climate change risks for forests

Science.gov (United States)

Allen, Craig D.; Macalady, A.K.; Chenchouni, H.; Bachelet, D.; McDowell, N.; Vennetier, Michel; Kitzberger, T.; Rigling, A.; Breshears, D.D.; Hogg, E.H.(T.); Gonzalez, P.; Fensham, R.; Zhang, Z.; Castro, J.; Demidova, N.; Lim, J.-H.; Allard, G.; Running, S.W.; Semerci, A.; Cobb, N.

2010-01-01

Greenhouse gas emissions have significantly altered global climate, and will continue to do so in the future. Increases in the frequency, duration, and/or severity of drought and heat stress associated with climate change could fundamentally alter the composition, structure, and biogeography of forests in many regions. Of particular concern are potential increases in tree mortality associated with climate-induced physiological stress and interactions with other climate-mediated processes such as insect outbreaks and wildfire. Despite this risk, existing projections of tree mortality are based on models that lack functionally realistic mortality mechanisms, and there has been no attempt to track observations of climate-driven tree mortality globally. Here we present the first global assessment of recent tree mortality attributed to drought and heat stress. Although episodic mortality occurs in the absence of climate change, studies compiled here suggest that at least some of the world's forested ecosystems already may be responding to climate change and raise concern that forests may become increasingly vulnerable to higher background tree mortality rates and die-off in response to future warming and drought, even in environments that are not normally considered water-limited. This further suggests risks to ecosystem services, including the loss of sequestered forest carbon and associated atmospheric feedbacks. Our review also identifies key information gaps and scientific uncertainties that currently hinder our ability to predict tree mortality in response to climate change and emphasizes the need for a globally coordinated observation system. Overall, our review reveals the potential for amplified tree mortality due to drought and heat in forests worldwide.

An improved Peltier effect-based instrument for critical temperature threshold measurement in cold- and heat-induced urticaria.

Science.gov (United States)

Magerl, M; Abajian, M; Krause, K; Altrichter, S; Siebenhaar, F; Church, M K

2015-10-01

Cold- and heat-induced urticaria are chronic physical urticaria conditions in which wheals, angioedema or both are evoked by skin exposure to cold and heat respectively. The diagnostic work up of both conditions should include skin provocation tests and accurate determination of critical temperature thresholds (CTT) for producing symptoms in order to be able to predict the potential risk that each individual patient faces and how this may be ameliorated by therapy. To develop and validate TempTest(®) 4, a simple and relatively inexpensive instrument for the accurate determination of CTT which may be used in clinical practice. TempTest(®) 4 has a single 2 mm wide 350 mm U-shaped Peltier element generating a temperature gradient from 4 °C to 44 °C along its length. Using a clear plastic guide placed over the skin after provocation, CTT values may be determined with an accuracy of ±1 °C. Here, TempTest(®) 4 was compared with its much more expensive predecessor, TempTest(®) 3, in inducing wheals in 30 cold urticaria patients. Both TempTest(®) 4 and TempTest(®) 3 induced wheals in all 30 patients between 8 ° and 28 °C. There was a highly significant (P < 0.0001) correlation between the instruments in the CTT values in individual patients. The TempTest(®) 4 is a simple, easy to use, licensed, commercially available and affordable instrument for the determination of CTTs in both cold- and heat-induced urticaria. © 2014 European Academy of Dermatology and Venereology.

Electron beam induced Hg desorption and the electronic structure of the Hg depleted surface of Hg1/sub -//sub x/Cd/sub x/Te

International Nuclear Information System (INIS)

Shih, C.K.; Friedman, D.J.; Bertness, K.A.; Lindau, I.; Spicer, W.E.; Wilson, J.A.

1986-01-01

Auger electron spectroscopy (AES), x-ray photoemission spectroscopy (XPS), low energy electron diffraction (LEED), and angle-resolved ultraviolet photoemission spectroscopy (ARPES) were used to study the electron beam induced Hg desorption from a cleaved (110)Hg/sub 1-//sub x/Cd/sub x/Te surface and the electronic structure of the Hg depleted surface. Solid state recrystallized Hg/sub 1-//sub x/Cd/sub x/Te single crystals were used. It was found that the electron beam heating dominated the electron beam induced Hg desorption on Hg/sub 1-//sub x/Cd/sub x/Te. At the electron beam energy used, the electron beam heating extended several thousand angstroms deep. However, the Hg depletion saturated after a few monolayers were depleted of Hg atoms. At the initial stage of Hg loss (only 3%), the surface band bends upward (more p type). The ARPES spectrum showed the loss of some E vs k dispersion after 22% Hg atoms were removed from the surface region, and no dispersion was observed after 43% Hg atoms were removed. These results have important implications on the electronic structure of the surfaces and interfaces of which the stoichiometry is altered

Modeling of fuel vapor jet eruption induced by local droplet heating

KAUST Repository

Sim, Jaeheon

2014-01-10

The evaporation of a droplet by non-uniform heating is numerically investigated in order to understand the mechanism of the fuel-vapor jet eruption observed in the flame spread of a droplet array under microgravity condition. The phenomenon was believed to be mainly responsible for the enhanced flame spread rate through a droplet cloud at microgravity conditions. A modified Eulerian-Lagrangian method with a local phase change model is utilized to describe the interfacial dynamics between liquid droplet and surrounding air. It is found that the localized heating creates a temperature gradient along the droplet surface, induces the corresponding surface tension gradient, and thus develops an inner flow circulation commonly referred to as the Marangoni convection. Furthermore, the effect also produces a strong shear flow around the droplet surface, thereby pushing the fuel vapor toward the wake region of the droplet to form a vapor jet eruption. A parametric study clearly demonstrated that at realistic droplet combustion conditions the Marangoni effect is indeed responsible for the observed phenomena, in contrast to the results based on constant surface tension approximation

The quinone methide aurin is a heat shock response inducer that causes proteotoxic stress and Noxa-dependent apoptosis in malignant melanoma cells.

Science.gov (United States)

Davis, Angela L; Qiao, Shuxi; Lesson, Jessica L; Rojo de la Vega, Montserrat; Park, Sophia L; Seanez, Carol M; Gokhale, Vijay; Cabello, Christopher M; Wondrak, Georg T

2015-01-16

Pharmacological induction of proteotoxic stress is rapidly emerging as a promising strategy for cancer cell-directed chemotherapeutic intervention. Here, we describe the identification of a novel drug-like heat shock response inducer for the therapeutic induction of proteotoxic stress targeting malignant human melanoma cells. Screening a focused library of compounds containing redox-directed electrophilic pharmacophores employing the Stress & Toxicity PathwayFinder(TM) PCR Array technology as a discovery tool, a drug-like triphenylmethane-derivative (aurin; 4-[bis(p-hydroxyphenyl)methylene]-2,5-cyclohexadien-1-one) was identified as an experimental cell stress modulator that causes (i) heat shock factor transcriptional activation, (ii) up-regulation of heat shock response gene expression (HSPA6, HSPA1A, DNAJB4, HMOX1), (iii) early unfolded protein response signaling (phospho-PERK, phospho-eIF2α, CHOP (CCAAT/enhancer-binding protein homologous protein)), (iv) proteasome impairment with increased protein-ubiquitination, and (v) oxidative stress with glutathione depletion. Fluorescence polarization-based experiments revealed that aurin displays activity as a geldanamycin-competitive Hsp90α-antagonist, a finding further substantiated by molecular docking and ATPase inhibition analysis. Aurin exposure caused caspase-dependent cell death in a panel of human malignant melanoma cells (A375, G361, LOX-IMVI) but not in non-malignant human skin cells (Hs27 fibroblasts, HaCaT keratinocytes, primary melanocytes) undergoing the aurin-induced heat shock response without impairment of viability. Aurin-induced melanoma cell apoptosis depends on Noxa up-regulation as confirmed by siRNA rescue experiments demonstrating that siPMAIP1-based target down-regulation suppresses aurin-induced cell death. Taken together, our data suggest feasibility of apoptotic elimination of malignant melanoma cells using the quinone methide-derived heat shock response inducer aurin. © 2015 by The

Future heat supply of our cities. Heating by waste heat

Energy Technology Data Exchange (ETDEWEB)

Brachetti, H E [Stadtwerke Hannover A.G. (Germany, F.R.); Technische Univ. Hannover (Germany, F.R.))

1976-08-01

The energy-price crisis resulted in structural changes of the complete energy supply and reactivated the question of energy management with respect to the optimum solution of meeting the energy requirements for space heating. Condensation power plants are increasingly replaced by thermal stations, the waste heat of which is used as so-called district heat. Thermal power stations must be situated close to urban areas. The problem of emission of harmful materials can partly be overcome by high-level emission. The main subject of the article, however, is the problem of conducting and distributing the heat. The building costs of heat pipeline systems and the requirements to be met by heat pipelines such as strength, heat insulation and protection against humidity and ground water are investigated.

Heat waves measured with MODIS land surface temperature data predict changes in avian community structure

Science.gov (United States)

Thomas P. Albright; Anna M. Pidgeon; Chadwick D. Rittenhouse; Murray K. Clayton; Curtis H. Flather; Patrick D. Culbert; Volker C. Radeloff

2011-01-01

Heat waves are expected to become more frequent and severe as climate changes, with unknown consequences for biodiversity. We sought to identify ecologically-relevant broad-scale indicators of heat waves based on MODIS land surface temperature (LST) and interpolated air temperature data and assess their associations with avian community structure. Specifically, we...

Changes induced in a ZnS:Cr-based electroluminescent waveguide structure by intrinsic near-infrared laser radiation

International Nuclear Information System (INIS)

Vlasenko, N. A.; Oleksenko, P. F.; Mukhlyo, M. A.; Veligura, L. I.

2013-01-01

The causes of changes that occur in a thin-film electroluminescent metal-insulator-semiconductor-insulator-metal waveguide structure based on ZnS:Cr (Cr concentration of ∼4 × 10 20 cm −3 ) upon lasing (λ ≈ 2.6 μm) and that induce lasing cessation are studied. It is established that lasing ceases because of light-scattering inhomogeneities formed in the structure and, hence, optical losses enhance. The origin of the inhomogeneities and the causes of their formation are clarified by studying the surface topology and the crystal structure of constituent layers of the samples before and after lasing. The studies are performed by means of atomic force microscopy and X-ray radiography. It is shown that a substantial increase in the sizes of grains on the surface of the structure is the manifestation of changes induced in the ZnS:Cr film by recrystallization. Recrystallization is initiated by local heating by absorbed laser radiation in existing Cr clusters and quickened by a strong electric field (>1 MV cm −1 ). The changes observed in the ZnS:Cr film are as follows: the textured growth of ZnS crystallites, an increase in the content of Cr clusters, and the appearance of some CrS and a rather high ZnO content. Some ways for improving the stability of lasing in the ZnS:Cr-based waveguide structures are proposed

Subharmonic energy-gap structure and heating effects in superconducting niobium point contacts

DEFF Research Database (Denmark)

Flensberg, K.; Hansen, Jørn Bindslev

1989-01-01

We present experimental data of the temperature-dependent subharmonic energy-gap structure (SGS) in the current-voltage (I-V) curves of superconducting niobium point contacts. The observed SGS is modified by heating effects. We construct a model of the quasiparticle conductance of metallic...

Heat resistant/radiation resistant cable and incore structure test device for FBR type reactor

International Nuclear Information System (INIS)

Tanimoto, Hajime; Shiono, Takeo; Sato, Yoshimi; Ito, Kazumi; Sudo, Shigeaki; Saito, Shin-ichi; Mitsui, Hisayasu.

1995-01-01

A heat resistant/radiation resistant coaxial cable of the present invention comprises an insulation layer, an outer conductor and a protection cover in this order on an inner conductor, in which the insulation layer comprises thermoplastic polyimide. In the same manner, a heat resistant/radiation resistant power cable has an insulation layer comprising thermoplastic polyimide on a conductor, and is provided with a protection cover comprising braid of alamide fibers at the outer circumference of the insulation layer. An incore structure test device for an FBR type reactor comprises the heat resistant/radiation resistant coaxial cable and/or the power cable. The thermoplastic polyimide can be extrusion molded, and has excellent radiation resistant by the extrusion, as well as has high dielectric withstand voltage, good flexibility and electric characteristics at high temperature. The incore structure test device for the FBR type reactor of the present invention comprising such a cable has excellent reliability and durability. (T.M.)

Effect of short-term exercise-heat acclimation on ventilatory and cerebral blood flow responses to passive heating at rest in humans.

Science.gov (United States)

Fujii, Naoto; Tsuji, Bun; Honda, Yasushi; Kondo, Narihiko; Nishiyasu, Takeshi

2015-09-01

Hyperthermia induces hyperventilation and cerebral hypoperfusion in resting humans. We tested the hypothesis that short-term exercise-heat acclimation would alleviate those effects. Twenty healthy male subjects were divided into two groups that performed exercise training in the heat (TR-HEAT, n = 10) or cold (TR-COLD, n = 10). Before and after the training, the subjects in both groups participated in passive-heat tests at rest. Training was performed at 37°C (TR-HEAT) or 10°C (TR-COLD) and entailed four 20-min bouts of cycling at 50% peak oxygen uptake separated by 10-min recoveries daily for 6 consecutive days. After TR-HEAT, esophageal temperature was lowered when measured before and during passive heating, as was the esophageal temperature threshold for cutaneous active vasodilation, whereas plasma volume was increased (all P heat acclimation were not all induced by TR-COLD (all P > 0.05). TR-HEAT had no significant effect on passive heating-induced increases in minute ventilation, even when evaluated as the esophageal temperature threshold for increases in minute ventilation and the slope relating minute ventilation to esophageal temperature (all P > 0.05). By contrast, TR-HEAT attenuated the passive heating-induced reduction in the cerebral vascular conductance index (middle cerebral artery mean blood velocity/mean arterial pressure) (all P heating (all P > 0.05). These data suggest that in resting heated humans, short-term heat acclimation achieved through moderate-intensity exercise training (i.e., 50% peak oxygen uptake) in the heat does not influence hyperthermia-induced hyperventilation, but it does potentially attenuate cerebral hypoperfusion. Copyright © 2015 the American Physiological Society.

Metabolite responses to exogenous application of nitrogen, cytokinin, and ethylene inhibitors in relation to heat-induced senescence in creeping bentgrass.

Directory of Open Access Journals (Sweden)

David Jespersen

Full Text Available The exogenous application of ethylene inhibitors, cytokinins, or nitrogen has previously been shown to suppress heat-induced senescence and improve heat tolerance in cool-season grasses. The objectives of this study were to examine metabolic profiles altered by exogenous treatment of creeping bentgrass with an ethylene inhibitor, cytokinin or nitrogen under heat stress and to determine metabolic pathways regulated by those compounds in association with their effectiveness for improving heat tolerance. Creeping bentgrass (Agostis stolonifera plants (cv. Penncross were foliar sprayed with 18 mM carbonyldiamide (N source, 25 μM aminoethoxyvinylglycine (AVG, ethylene inhibitor, 25 μM zeatin riboside (ZR, cytokinin, or a water control, and then exposed to 20/15°C (day/night or 35/30°C (heat stress in growth chambers. All three exogenous treatments suppressed leaf senescence, as manifested by increased turf quality and chlorophyll content, and reduced electrolyte leakage under heat stress. Polar metabolite profiling identified increases in the content of certain organic acids (i.e. citric and malic acid, sugar alcohols, disaccharides (sucrose, and decreased accumulations of monosaccharides (i.e. glucose and fructose with exogenous treatment of N, AVG, or ZR at the previously mentioned concentrations when compared to the untreated control under heat stress. Nitrogen stimulated amino acid accumulation whereas AVG and ZR reduced amino acid accumulation compared to the untreated control under heat stress. These results revealed that the alleviation of heat-induced leaf senescence by N, AVG, and ZR could be due to changes in the accumulation of metabolites involved in osmoregulation, antioxidant metabolism, carbon and nitrogen metabolism, as well as stress signaling molecules.

Planform structure and heat transfer in turbulent free convection over horizontal surfaces

Science.gov (United States)

Theerthan, S. Ananda; Arakeri, Jaywant H.

2000-04-01

This paper deals with turbulent free convection in a horizontal fluid layer above a heated surface. Experiments have been carried out on a heated surface to obtain and analyze the planform structure and the heat transfer under different conditions. Water is the working fluid and the range of flux Rayleigh numbers (Ra) covered is 3×107-2×1010. The different conditions correspond to Rayleigh-Bénard convection, convection with either the top water surface open to atmosphere or covered with an insulating plate, and with an imposed external flow on the heated boundary. Without the external flow the planform is one of randomly oriented line plumes. At large Rayleigh number Ra and small aspect ratio (AR), these line plumes seem to align along the diagonal, presumably due to a large scale flow. The side views show inclined dyelines, again indicating a large scale flow. When the external flow is imposed, the line plumes clearly align in the direction of external flow. The nondimensional average plume spacing, Raλ1/3, varies between 40 and 90. The heat transfer rate, for all the experiments conducted, represented as RaδT-1/3, where δT is the conduction layer thickness, varies only between 0.1-0.2, showing that in turbulent convection the heat transfer rates are similar under the different conditions.

Surface properties of heat-induced soluble soy protein aggregates of different molecular masses.

Science.gov (United States)

Guo, Fengxian; Xiong, Youling L; Qin, Fang; Jian, Huajun; Huang, Xiaolin; Chen, Jie

2015-02-01

Suspensions (2% and 5%, w/v) of soy protein isolate (SPI) were heated at 80, 90, or 100 °C for different time periods to produce soluble aggregates of different molecular sizes to investigate the relationship between particle size and surface properties (emulsions and foams). Soluble aggregates generated in these model systems were characterized by gel permeation chromatography and sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Heat treatment increased surface hydrophobicity, induced SPI aggregation via hydrophobic interaction and disulfide bonds, and formed soluble aggregates of different sizes. Heating of 5% SPI always promoted large-size aggregate (LA; >1000 kDa) formation irrespective of temperature, whereas the aggregate size distribution in 2% SPI was temperature dependent: the LA fraction progressively rose with temperature (80→90→100 °C), corresponding to the attenuation of medium-size aggregates (MA; 670 to 1000 kDa) initially abundant at 80 °C. Heated SPI with abundant LA (>50%) promoted foam stability. LA also exhibited excellent emulsifying activity and stabilized emulsions by promoting the formation of small oil droplets covered with a thick interfacial protein layer. However, despite a similar influence on emulsion stability, MA enhanced foaming capacity but were less capable of stabilizing emulsions than LA. The functionality variation between heated SPI samples is clearly related to the distribution of aggregates that differ in molecular size and surface activity. The findings may encourage further research to develop functional SPI aggregates for various commercial applications. © 2015 Institute of Food Technologists®

Development of linear projecting in studies of non-linear flow. Acoustic heating induced by non-periodic sound

Energy Technology Data Exchange (ETDEWEB)

Perelomova, Anna [Gdansk University of Technology, Faculty of Applied Physics and Mathematics, ul. Narutowicza 11/12, 80-952 Gdansk (Poland)]. E-mail: anpe@mif.pg.gda.pl

2006-08-28

The equation of energy balance is subdivided into two dynamics equations, one describing evolution of the dominative sound, and the second one responsible for acoustic heating. The first one is the famous KZK equation, and the second one is a novel equation governing acoustic heating. The novel dynamic equation considers both periodic and non-periodic sound. Quasi-plane geometry of flow is supposed. Subdividing is provided on the base of specific links of every mode. Media with arbitrary thermic T(p,{rho}) and caloric e(p,{rho}) equations of state are considered. Individual roles of thermal conductivity and viscosity in the heating induced by aperiodic sound in the ideal gases and media different from ideal gases are discussed.

Development of linear projecting in studies of non-linear flow. Acoustic heating induced by non-periodic sound

Science.gov (United States)

Perelomova, Anna

2006-08-01

The equation of energy balance is subdivided into two dynamics equations, one describing evolution of the dominative sound, and the second one responsible for acoustic heating. The first one is the famous KZK equation, and the second one is a novel equation governing acoustic heating. The novel dynamic equation considers both periodic and non-periodic sound. Quasi-plane geometry of flow is supposed. Subdividing is provided on the base of specific links of every mode. Media with arbitrary thermic T(p,ρ) and caloric e(p,ρ) equations of state are considered. Individual roles of thermal conductivity and viscosity in the heating induced by aperiodic sound in the ideal gases and media different from ideal gases are discussed.

Development of linear projecting in studies of non-linear flow. Acoustic heating induced by non-periodic sound

International Nuclear Information System (INIS)

Perelomova, Anna

2006-01-01

The equation of energy balance is subdivided into two dynamics equations, one describing evolution of the dominative sound, and the second one responsible for acoustic heating. The first one is the famous KZK equation, and the second one is a novel equation governing acoustic heating. The novel dynamic equation considers both periodic and non-periodic sound. Quasi-plane geometry of flow is supposed. Subdividing is provided on the base of specific links of every mode. Media with arbitrary thermic T(p,ρ) and caloric e(p,ρ) equations of state are considered. Individual roles of thermal conductivity and viscosity in the heating induced by aperiodic sound in the ideal gases and media different from ideal gases are discussed

Effects of heat-moisture treatment reaction conditions on the physicochemical and structural properties of maize starch: moisture and length of heating.

Science.gov (United States)

Sui, Zhongquan; Yao, Tianming; Zhao, Yue; Ye, Xiaoting; Kong, Xiangli; Ai, Lianzhong

2015-04-15

Changes in the properties of normal maize starch (NMS) and waxy maize starch (WMS) after heat-moisture treatment (HMT) under various reaction conditions were investigated. NMS and WMS were adjusted to moisture levels of 20%, 25% and 30% and heated at 100 °C for 2, 4, 8 and 16 h. The results showed that moisture content was the most important factor in determining pasting properties for NMS, whereas the heating length was more important for WMS. Swelling power decreased in NMS but increased in WMS, and while the solubility index decreased for both samples, the changes were largely determined by moisture content. The gelatinisation temperatures of both samples increased with increasing moisture content but remained unchanged with increasing heating length. The Fourier transform infrared (FT-IR) absorbance ratio was affected to different extents by the moisture levels but remained constant with increasing the heating length. The X-ray intensities increased but relative crystallinity decreased to a greater extent with increasing moisture content. This study showed that the levels of moisture content and length of heating had significant impacts on the structural and physicochemical properties of normal and waxy maize starches but to different extents. Copyright © 2014 Elsevier Ltd. All rights reserved.

Flow-induced vibrations of circular cylindrical structures

International Nuclear Information System (INIS)

Chen, S.

1977-06-01

The problems of flow-induced vibrations of circular cylindrical structures are reviewed. First, the general method of analysis and classification of structural responses are presented. Then, the presentation is broken up along the lines with stationary fluid, parallel flow, and cross flow. Finally, design considerations and future research needs are pointed out. 234 references

Live and Heat-Killed Lactobacillus rhamnosus ATCC 7469 May Induce Modulatory Cytokines Profiles on Macrophages RAW 264.7.

Science.gov (United States)

Jorjão, Adeline Lacerda; de Oliveira, Felipe Eduardo; Leão, Mariella Vieira Pereira; Carvalho, Cláudio Antonio Talge; Jorge, Antonio Olavo Cardoso; de Oliveira, Luciane Dias

2015-01-01

This study aimed to evaluate the capacity of Lactobacillus rhamnosus and/or its products to induce the synthesis of cytokines (TNF-α, IL-1β, IL-4, IL-6, IL-10, and IL-12) by mouse macrophages (RAW 264.7). Three microorganism preparations were used: live L. rhamnosus (LLR) suspension, heat-killed L. rhamnosus (HKLR) suspension, and the supernatant of a heat-killed L. rhamnosus (SHKLR) suspension, which were cultured with macrophages (37°C, 5% CO2) for 2 h and 30 min. After that, cells were cultured for 16 h. The supernatants were used for the quantitation of cytokines, by ELISA. The results were compared with the synthesis induced by lipopolysaccharide (LPS) and analysed, using ANOVA and Tukey test, 5%. LLR and HKLR groups were able to significantly increase the production of TNF-α, IL-6, and IL-10 (P 0.05). All the L. rhamnosus suspensions were not able to produce detectable levels of IL-1β or significant levels of IL-4 and IL-12 (P > 0.05). In conclusion, live and heat-killed L. rhamnosus suspensions were able to induce the synthesis of different cytokines with proinflammatory (TNF-α and IL-6) or regulatory (IL-10) functions, suggesting the role of strain L. rhamnosus ATCC 7469 in the modulation or in the stimulation of immune responses.

Live and Heat-Killed Lactobacillus rhamnosus ATCC 7469 May Induce Modulatory Cytokines Profiles on Macrophages RAW 264.7

Directory of Open Access Journals (Sweden)

Adeline Lacerda Jorjão

2015-01-01

Full Text Available This study aimed to evaluate the capacity of Lactobacillus rhamnosus and/or its products to induce the synthesis of cytokines (TNF-α, IL-1β, IL-4, IL-6, IL-10, and IL-12 by mouse macrophages (RAW 264.7. Three microorganism preparations were used: live L. rhamnosus (LLR suspension, heat-killed L. rhamnosus (HKLR suspension, and the supernatant of a heat-killed L. rhamnosus (SHKLR suspension, which were cultured with macrophages (37°C, 5% CO2 for 2 h and 30 min. After that, cells were cultured for 16 h. The supernatants were used for the quantitation of cytokines, by ELISA. The results were compared with the synthesis induced by lipopolysaccharide (LPS and analysed, using ANOVA and Tukey test, 5%. LLR and HKLR groups were able to significantly increase the production of TNF-α, IL-6, and IL-10 (P0.05. All the L. rhamnosus suspensions were not able to produce detectable levels of IL-1β or significant levels of IL-4 and IL-12 (P>0.05. In conclusion, live and heat-killed L. rhamnosus suspensions were able to induce the synthesis of different cytokines with proinflammatory (TNF-α and IL-6 or regulatory (IL-10 functions, suggesting the role of strain L. rhamnosus ATCC 7469 in the modulation or in the stimulation of immune responses.

Structural, dynamic, and vibrational properties during heat transfer in Si/Ge superlattices: A Car-Parrinello molecular dynamics study

Energy Technology Data Exchange (ETDEWEB)

Ji, Pengfei; Zhang, Yuwen, E-mail: zhangyu@missouri.edu [Department of Mechanical and Aerospace Engineering, University of Missouri, Columbia, Missouri 65211 (United States); Yang, Mo [College of Energy and Power Engineering, University of Shanghai for Science and Technology, Shanghai 200093 (China)

2013-12-21

The structural, dynamic, and vibrational properties during heat transfer process in Si/Ge superlattices are studied by analyzing the trajectories generated by the ab initio Car-Parrinello molecular dynamics simulation. The radial distribution functions and mean square displacements are calculated and further discussions are made to explain and probe the structural changes relating to the heat transfer phenomenon. Furthermore, the vibrational density of states of the two layers (Si/Ge) are computed and plotted to analyze the contributions of phonons with different frequencies to the heat conduction. Coherent heat conduction of the low frequency phonons is found and their contributions to facilitate heat transfer are confirmed. The Car-Parrinello molecular dynamics simulation outputs in the work show reasonable thermophysical results of the thermal energy transport process and shed light on the potential applications of treating the heat transfer in the superlattices of semiconductor materials from a quantum mechanical molecular dynamics simulation perspective.

Structural, dynamic, and vibrational properties during heat transfer in Si/Ge superlattices: A Car-Parrinello molecular dynamics study

International Nuclear Information System (INIS)

Ji, Pengfei; Zhang, Yuwen; Yang, Mo

2013-01-01

The structural, dynamic, and vibrational properties during heat transfer process in Si/Ge superlattices are studied by analyzing the trajectories generated by the ab initio Car-Parrinello molecular dynamics simulation. The radial distribution functions and mean square displacements are calculated and further discussions are made to explain and probe the structural changes relating to the heat transfer phenomenon. Furthermore, the vibrational density of states of the two layers (Si/Ge) are computed and plotted to analyze the contributions of phonons with different frequencies to the heat conduction. Coherent heat conduction of the low frequency phonons is found and their contributions to facilitate heat transfer are confirmed. The Car-Parrinello molecular dynamics simulation outputs in the work show reasonable thermophysical results of the thermal energy transport process and shed light on the potential applications of treating the heat transfer in the superlattices of semiconductor materials from a quantum mechanical molecular dynamics simulation perspective

Structural, dynamic, and vibrational properties during heat transfer in Si/Ge superlattices: A Car-Parrinello molecular dynamics study

Science.gov (United States)

Ji, Pengfei; Zhang, Yuwen; Yang, Mo

2013-12-01

The structural, dynamic, and vibrational properties during heat transfer process in Si/Ge superlattices are studied by analyzing the trajectories generated by the ab initio Car-Parrinello molecular dynamics simulation. The radial distribution functions and mean square displacements are calculated and further discussions are made to explain and probe the structural changes relating to the heat transfer phenomenon. Furthermore, the vibrational density of states of the two layers (Si/Ge) are computed and plotted to analyze the contributions of phonons with different frequencies to the heat conduction. Coherent heat conduction of the low frequency phonons is found and their contributions to facilitate heat transfer are confirmed. The Car-Parrinello molecular dynamics simulation outputs in the work show reasonable thermophysical results of the thermal energy transport process and shed light on the potential applications of treating the heat transfer in the superlattices of semiconductor materials from a quantum mechanical molecular dynamics simulation perspective.

Structural integrity assessment of intermediate heat exchanger in the HTTR. Based on results of rise-to-power test

Energy Technology Data Exchange (ETDEWEB)

Takeda, Takeshi; Tachibana, Yukio; Nakagawa, Shigeaki [Japan Atomic Energy Research Inst., Oarai, Ibaraki (Japan). Oarai Research Establishment

2002-12-01

A helium/helium intermediate heat exchanger (IHX) in the high temperature engineering test reactor (HTTR) is an essential component for demonstration of future nuclear process heat utilization of high temperature gas-cooled reactor (HTGR). The IHX with a heat capacity of 10 MW has 96 helically-coiled heat transfer tubes. Structural design for the IHX had been conducted through elastic-creep analysis of superalloy Hastelloy XR components such as heat transfer tubes and center pipe. In the HTTR rise-to-power test, it was clarified that temperature of the coolant in the IHX at the reactor scrams changes more rapidly than expected in the design. Effects of the IHX coolant temperature change, at anticipated reactor scram from the full power of 30 MW at high temperature test operation, on structural integrity of the heat transfer tubes and the lower reducer of the center pipe were investigated analytically based on the coolant temperature data obtained from the rise-to-power test. As results of the assessment, it was confirmed that cumulative principal creep strain, cumulative creep and fatigue damage factor of the IHX components during 10{sup 5} h of the HTTR lifetime should be below the allowable limits, which are established in the high-temperature structural design code for the HTGR Class 1 components. (author)

Use of a laser-induced fluorescence thermal imaging system for film cooling heat transfer measurement

Energy Technology Data Exchange (ETDEWEB)

Chyu, M.K. [Carnegie Mellon Univ., Pittsburgh, PA (United States)

1995-10-01

This paper describes a novel approach based on fluorescence imaging of thermographic phosphor that enables the simultaneous determination of both local film effectiveness and local heat transfer on a film-cooled surface. The film cooling model demonstrated consists of a single row of three discrete holes on a flat plate. The transient temperature measurement relies on the temperature-sensitive fluorescent properties of europium-doped lanthanum oxysulfide (La{sub 2}O{sub 2}S:EU{sup 3+}) thermographic phosphor. A series of full-field surface temperatures, mainstream temperatures, and coolant film temperatures were acquired during the heating of a test surface. These temperatures are used to calculate the heat transfer coefficients and the film effectiveness simultaneously. Because of the superior spatial resolution capability for the heat transfer data reduced from these temperature frames, the laser-induced fluorescence (LIF) imaging system, the present study observes the detailed heat transfer characteristics over a film-protected surface. The trend of the results agrees with those obtained using other conventional thermal methods, as well as the liquid crystal imaging technique. One major advantage of this technique is the capability to record a large number of temperature frames over a given testing period. This offers multiple-sample consistency.

Effects of a heat shock protein inducer on the atrial fibrillation substrate caused by acute atrial ischaemia

NARCIS (Netherlands)

Sakabe, Masao; Shiroshita-Takeshita, Akiko; Maguy, Ange; Brundel, Bianca J. J. M.; Fujiki, Akira; Inoue, Hiroshi; Nattel, Stanley

2008-01-01

Aims Heat shock proteins (HSPs) are a set of endogenous cytoprotective factors activated by various pathological conditions. This study addressed the effects of geranylgeranylacetone (GGA), an orally active HSP inducer, on the atrial fibrillation (AF) substrate associated with acute atria( ischaemia

Code ACTIVE for calculation of the transmutation, induced activity and decay heat in neutron irradiation

International Nuclear Information System (INIS)

Ioki, Kimihiro; Harada, Yuhei; Asami, Naoto.

1976-03-01

The computer code ACTIVE has been prepared for calculation of the transmutation rate, induced activity and decay heat. Calculations are carried out with activation chain and spatial distribution of neutron energy spectrum. The spatial distribution of secondary gamma-ray source due to the unstable nuclides is also obtainable. Special attension is paid to the short life decays. (auth.)

Wheat chloroplast targeted sHSP26 promoter confers heat and abiotic stress inducible expression in transgenic Arabidopsis Plants.

Directory of Open Access Journals (Sweden)

Neetika Khurana

Full Text Available The small heat shock proteins (sHSPs have been found to play a critical role in physiological stress conditions in protecting proteins from irreversible aggregation. To characterize the hloroplast targeted sHSP26 promoter in detail, deletion analysis of the promoter is carried out and analysed via transgenics in Arabidopsis. In the present study, complete assessment of the importance of CCAAT-box elements along with Heat shock elements (HSEs in the promoter of sHSP26 was performed. Moreover, the importance of 5' untranslated region (UTR has also been established in the promoter via Arabidopsis transgenics. An intense GUS expression was observed after heat stress in the transgenics harbouring a full-length promoter, confirming the heat-stress inducibility of the promoter. Transgenic plants without UTR showed reduced GUS expression when compared to transgenic plants with UTR as was confirmed at the RNA and protein levels by qRT-PCR and GUS histochemical assays, thus suggesting the possible involvement of some regulatory elements present in the UTR in heat-stress inducibility of the promoter. Promoter activity was also checked under different abiotic stresses and revealed differential expression in different deletion constructs. Promoter analysis based on histochemical assay, real-time qPCR and fluorimetric analysis revealed that HSEs alone could not transcribe GUS gene significantly in sHSP26 promoter and CCAAT box elements contribute synergistically to the transcription. Our results also provide insight into the importance of 5`UTR of sHsp26 promoter thus emphasizing the probable role of imperfect CCAAT-box element or some novel cis-element with respect to heat stress.

Heat induced fracturing of rock in an existing uniaxial stress field

International Nuclear Information System (INIS)

Mathis, J.; Stephansson, O.; Bjarnason, B.; Hakami, H.; Herdocia, A.; Mattila, U.; Singh, U.

1986-01-01

This study was initiated under the premise that it may be possible to determine the state of stress in the earth's crust by heat induced fracturing of the rock surrounding a borehole. The theory involved is superficially simple, involving the superposition of the stress field around a borehole due to the existing virgin stresses and the uniform stress field of thermally loaded rock as induced by a heater. Since the heat stress field is uniform, varying only in magnitude and gradient as a function of heater input, fracturing should be controlled by the non-uniform virgin stress field. To determine if the method was, in fact, feasible, a series of laboratory test were conducted. These tests consisted of physically loading center drilled cubes of rock, 0.3 m on a side, uniaxially from 0 to 25 MPa. The blocks were then thermally loaded with a nominally rated 3.7 kW heater until failure occurred. Results from these laboratory tests were then compared to analytical studies of the problem, i.e., finite element and discrete theoretical analysis. Overall, results were such that the method is likely eliminated as a stress measurement technique. The immediate development of a thermal compressive zone on the borehole wall overlaps the tensile zone created by the uniaxial stress field, forcing the failure is thus controlled largely by the power input of the heater, being retarded by the small compressive stresses genrated by the uniaxial stress field. This small retardation effect is of such low magnitude that the retardation effect is of such low magnitude that the fracture time is relatively insensitive to the local virgin stress field. (authors)

Imaging of artificially induced vortex structures

International Nuclear Information System (INIS)

Fasano, Yanina; Menghini, M.; Cruz, F. de la

2004-01-01

The combination of engineered pinning potentials in superconducting crystals, the detection of the liquid-solid vortex transition and the observation of the vortex structure with single vortex sensitivity allow the microscopic analysis of the response of 3D elastic systems to the presence of these potentials. In this work we review recent results obtained by a combination of those techniques studying different vortex structure induced transformations. On the one hand, we have visualized the transformation, along the vortex direction, of a bulk vortex single crystal with hexagonal symmetry into another crystal with square symmetry induced by an engineered Fe-dot lattice deposited on a surface of the vortex single crystal. On the other hand, we found an infrequent first-order phase transition where a vortex liquid under the presence of a random correlated potential (columnar defects) transforms into a vortex solid with no change of topological order

The long-term effects of a life-prolonging heat treatment on the Drosophila melanogaster transcriptome suggest that heat shock proteins extend lifespan

DEFF Research Database (Denmark)

Sarup, Pernille Merete; Sørensen, Peter; Loeschcke, Volker

2014-01-01

Heat-induced hormesis, i.e. the beneficial effect of mild heat-induced stress, increases the average lifespan of many organisms. This effect, which depends on the heat shock factor, decreases the log mortality rate weeks after the stress has ceased. To identify candidate genes that mediate......-treated flies. Several hsp70 probe sets were up-regulated 1.7–2-fold in the mildly stressed flies weeks after the last heat treatment (P shock protein, Hsp70, is reported to return to normal levels of expression shortly after heat stress. We...... conclude that the heat shock response, and Hsp70 in particular, may be central to the heat-induced increase in the average lifespan in flies that are exposed to mild heat stress early in life....

Theory and design of heat exchanger : air cooled plate, spiral heat exchanger

International Nuclear Information System (INIS)

Min, Ui Dong

1960-02-01

This book deals with air cooled heat exchanger, which introduces heat rejection system, wet surface cooler in new from, explanation of structure and design, materials, basic design like plenums chambers and fan ring, finned tube fouling factor, airflow in forced draft and fan design. It also tells of plate heat exchanger and spiral heat exchanger giving descriptions of summary, selection, basic design, device and safety function, maintenance, structure of plate heat exchanger, frames and connector plate and, basic things of spiral tube heat exchanger.

Magnetospheric structure and atmospheric Joule heating of habitable planets orbiting M-dwarf stars

Energy Technology Data Exchange (ETDEWEB)

Cohen, O.; Drake, J. J.; Garraffo, C.; Poppenhaeger, K. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Glocer, A. [NASA/GSFC, Code 673, Greenbelt, MD 20771 (United States); Bell, J. M. [Center for Planetary Atmospheres and Flight Sciences, National Institute of Aerospace, Hampton, VA 23666 (United States); Ridley, A. J.; Gombosi, T. I. [Center for Space Environment Modeling, University of Michigan, 2455 Hayward Street, Ann Arbor, MI 48109 (United States)

2014-07-20

We study the magnetospheric structure and the ionospheric Joule Heating of planets orbiting M-dwarf stars in the habitable zone using a set of magnetohydrodynamic models. The stellar wind solution is used to drive a model for the planetary magnetosphere, which is coupled with a model for the planetary ionosphere. Our simulations reveal that the space environment around close-in habitable planets is extreme, and the stellar wind plasma conditions change from sub- to super-Alfvénic along the planetary orbit. As a result, the magnetospheric structure changes dramatically with a bow shock forming in the super-Alfvénic sectors, while no bow shock forms in the sub-Alfvénic sectors. The planets reside most of the time in the sub-Alfvénic sectors with poor atmospheric protection. A significant amount of Joule Heating is provided at the top of the atmosphere as a result of the intense stellar wind. For the steady-state solution, the heating is about 0.1%-3% of the total incoming stellar irradiation, and it is enhanced by 50% for the time-dependent case. The significant Joule Heating obtained here should be considered in models for the atmospheres of habitable planets in terms of the thickness of the atmosphere, the top-side temperature and density, the boundary conditions for the atmospheric pressure, and particle radiation and transport. Here we assume constant ionospheric Pedersen conductance similar to that of the Earth. The conductance could be greater due to the intense EUV radiation leading to smaller heating rates. We plan to quantify the ionospheric conductance in future study.

Geothermal heat-pump systems of heat supply

International Nuclear Information System (INIS)

Vasil'ev, G.P.

2004-01-01

The data on the multilayer operation of the objects, located in the climatic conditions of the central area of Russia and equipped with the geothermal heat-pumping systems of the heat supply are presented. The results of the analytical studies on evaluating the geothermal heat-pumping systems of the heat supply integration efficiency into the structure of the energy supply system, prevailing in the country, are presented [ru

Thermal and mechanical effect during rapid heating of astroloy for improving structural integrity

International Nuclear Information System (INIS)

Popoolaa, A.P.I.; Oluwasegun, K.M.; Olorunniwo, O.E.; Atanda, P.O.; Aigbodion, V.S.

2016-01-01

The behaviour of γ′ phase to thermal and mechanical effects during rapid heating of Astroloy(Turbine Disc alloy) a Powder metallurgy (PM) nickel base superalloy has been investigated. The thermo-mechanical affected zone (TMAZ) and heat affected zone (HAZ) microstructure of an inertia friction welded Astroloy were simulated using a Gleeble thermo-mechanical simulation system. Detailed microstructural examination of the simulated TMAZ and HAZ and those present in actual inertial friction welded specimens showed that γ′ particles persisted during rapid heating up to a temperature where the formation of liquid is thermodynamically favoured, and subsequently re-solidified eutectically. The result obtained showed that forging during the thermo-mechanical simulation significantly enhanced resistance to weld liquation cracking of the alloy. This is attributable to strain-induced rapid isothermal dissolution of the constitutional liquation products within 150 μm from the centre of the forged sample. This was not observed in purely thermally simulated samples. The microstructure within the TMAZ of the as-welded alloy is similar to the microstructure in the forged Gleeble specimens. - Highlights: • The behaviour of γ′ phase to thermal and mechanical effects during rapid heating of Astrology • The thermo-mechanical affected zone (TMAZ) and heat affected zone (HAZ). • significantly enhanced resistance to weld liquation cracking of the alloy. • This was not observed in purely thermally simulated samples. • The microstructure within the TMAZ of the as-welded alloy is similar to the microstructure in the forged Gleeble specimens.

Thermal and mechanical effect during rapid heating of astroloy for improving structural integrity

Energy Technology Data Exchange (ETDEWEB)

Popoolaa, A.P.I., E-mail: popoolaapi@tut.ac.za [Department of Chemical, Metallurgical and Materials Engineering, Tshwane University of Technology, Pretoria (South Africa); Oluwasegun, K.M. [Department of Materials Science and Engineering, Obafemi Awolowo University (Nigeria); Olorunniwo, O.E., E-mail: segun_nniwo@yahoo.com [Department of Chemical, Metallurgical and Materials Engineering, Tshwane University of Technology, Pretoria (South Africa); Department of Materials Science and Engineering, Obafemi Awolowo University (Nigeria); Atanda, P.O. [Department of Materials Science and Engineering, Obafemi Awolowo University (Nigeria); Aigbodion, V.S. [Department of Chemical, Metallurgical and Materials Engineering, Tshwane University of Technology, Pretoria (South Africa); Department of Metallurgical and Materials Engineering, University of Nigeria, Nsukka (Nigeria)

2016-05-05

The behaviour of γ′ phase to thermal and mechanical effects during rapid heating of Astroloy(Turbine Disc alloy) a Powder metallurgy (PM) nickel base superalloy has been investigated. The thermo-mechanical affected zone (TMAZ) and heat affected zone (HAZ) microstructure of an inertia friction welded Astroloy were simulated using a Gleeble thermo-mechanical simulation system. Detailed microstructural examination of the simulated TMAZ and HAZ and those present in actual inertial friction welded specimens showed that γ′ particles persisted during rapid heating up to a temperature where the formation of liquid is thermodynamically favoured, and subsequently re-solidified eutectically. The result obtained showed that forging during the thermo-mechanical simulation significantly enhanced resistance to weld liquation cracking of the alloy. This is attributable to strain-induced rapid isothermal dissolution of the constitutional liquation products within 150 μm from the centre of the forged sample. This was not observed in purely thermally simulated samples. The microstructure within the TMAZ of the as-welded alloy is similar to the microstructure in the forged Gleeble specimens. - Highlights: • The behaviour of γ′ phase to thermal and mechanical effects during rapid heating of Astrology • The thermo-mechanical affected zone (TMAZ) and heat affected zone (HAZ). • significantly enhanced resistance to weld liquation cracking of the alloy. • This was not observed in purely thermally simulated samples. • The microstructure within the TMAZ of the as-welded alloy is similar to the microstructure in the forged Gleeble specimens.

Flow structure and heat exchange analysis in internal cooling channel of gas turbine blade

Science.gov (United States)

Szwaba, Ryszard; Kaczynski, Piotr; Doerffer, Piotr; Telega, Janusz

2016-08-01

This paper presents the study of the flow structure and heat transfer, and also their correlations on the four walls of a radial cooling passage model of a gas turbine blade. The investigations focus on heat transfer and aerodynamic measurements in the channel, which is an accurate representation of the configuration used in aeroengines. Correlations for the heat transfer coefficient and the pressure drop used in the design of radial cooling passages are often developed from simplified models. It is important to note that real engine passages do not have perfect rectangular cross sections, but include corner fillet, ribs with fillet radii and special orientation. Therefore, this work provides detailed fluid flow and heat transfer data for a model of radial cooling geometry which possesses very realistic features.

Lithium-ion battery structure that self-heats at low temperatures

Science.gov (United States)

Wang, Chao-Yang; Zhang, Guangsheng; Ge, Shanhai; Xu, Terrence; Ji, Yan; Yang, Xiao-Guang; Leng, Yongjun

2016-01-01

Lithium-ion batteries suffer severe power loss at temperatures below zero degrees Celsius, limiting their use in applications such as electric cars in cold climates and high-altitude drones. The practical consequences of such power loss are the need for larger, more expensive battery packs to perform engine cold cranking, slow charging in cold weather, restricted regenerative braking, and reduction of vehicle cruise range by as much as 40 per cent. Previous attempts to improve the low-temperature performance of lithium-ion batteries have focused on developing additives to improve the low-temperature behaviour of electrolytes, and on externally heating and insulating the cells. Here we report a lithium-ion battery structure, the ‘all-climate battery’ cell, that heats itself up from below zero degrees Celsius without requiring external heating devices or electrolyte additives. The self-heating mechanism creates an electrochemical interface that is favourable for high discharge/charge power. We show that the internal warm-up of such a cell to zero degrees Celsius occurs within 20 seconds at minus 20 degrees Celsius and within 30 seconds at minus 30 degrees Celsius, consuming only 3.8 per cent and 5.5 per cent of cell capacity, respectively. The self-heated all-climate battery cell yields a discharge/regeneration power of 1,061/1,425 watts per kilogram at a 50 per cent state of charge and at minus 30 degrees Celsius, delivering 6.4-12.3 times the power of state-of-the-art lithium-ion cells. We expect the all-climate battery to enable engine stop-start technology capable of saving 5-10 per cent of the fuel for 80 million new vehicles manufactured every year. Given that only a small fraction of the battery energy is used for self-heating, we envisage that the all-climate battery cell may also prove useful for plug-in electric vehicles, robotics and space exploration applications.

Lithium-ion battery structure that self-heats at low temperatures.

Science.gov (United States)

Wang, Chao-Yang; Zhang, Guangsheng; Ge, Shanhai; Xu, Terrence; Ji, Yan; Yang, Xiao-Guang; Leng, Yongjun

2016-01-28

Lithium-ion batteries suffer severe power loss at temperatures below zero degrees Celsius, limiting their use in applications such as electric cars in cold climates and high-altitude drones. The practical consequences of such power loss are the need for larger, more expensive battery packs to perform engine cold cranking, slow charging in cold weather, restricted regenerative braking, and reduction of vehicle cruise range by as much as 40 per cent. Previous attempts to improve the low-temperature performance of lithium-ion batteries have focused on developing additives to improve the low-temperature behaviour of electrolytes, and on externally heating and insulating the cells. Here we report a lithium-ion battery structure, the 'all-climate battery' cell, that heats itself up from below zero degrees Celsius without requiring external heating devices or electrolyte additives. The self-heating mechanism creates an electrochemical interface that is favourable for high discharge/charge power. We show that the internal warm-up of such a cell to zero degrees Celsius occurs within 20 seconds at minus 20 degrees Celsius and within 30 seconds at minus 30 degrees Celsius, consuming only 3.8 per cent and 5.5 per cent of cell capacity, respectively. The self-heated all-climate battery cell yields a discharge/regeneration power of 1,061/1,425 watts per kilogram at a 50 per cent state of charge and at minus 30 degrees Celsius, delivering 6.4-12.3 times the power of state-of-the-art lithium-ion cells. We expect the all-climate battery to enable engine stop-start technology capable of saving 5-10 per cent of the fuel for 80 million new vehicles manufactured every year. Given that only a small fraction of the battery energy is used for self-heating, we envisage that the all-climate battery cell may also prove useful for plug-in electric vehicles, robotics and space exploration applications.

Identification of proteins whose synthesis in Saccharomyces cerevisiae is induced by DNA damage and heat shock

International Nuclear Information System (INIS)

Gailit, James

1990-01-01

Protein synthesis in Saccharomyces cerevisiae after exposure to ultraviolet light (UV) was examined by two-dimensional gel electrophoresis of pulse-labelled proteins. The synthesis of 12 distinct proteins was induced by treatment with UV doses of 10-200 J/m 2 . The induced proteins differed in minimum dose necessary for induction, maximum dose at which induction still occurred and constitutive level present in unirradiated cells. A chemical mutagen, 4-nitroquinoline-1-oxide, induced synthesis of the same proteins. Induction after UV treatment was observed in seven different yeast strains, including three mutants deficient in DNA repair. Synthesis of five of the proteins was also induced by brief heat shock treatment. These five may be members of a family of proteins whose synthesis is regulated by two different pathways responding to different types of stress. (author)

Modeling of heat transfer into a heat pipe for a localized heat input zone

International Nuclear Information System (INIS)

Rosenfeld, J.H.

1987-01-01

A general model is presented for heat transfer into a heat pipe using a localized heat input. Conduction in the wall of the heat pipe and boiling in the interior structure are treated simultaneously. The model is derived from circumferential heat transfer in a cylindrical heat pipe evaporator and for radial heat transfer in a circular disk with boiling from the interior surface. A comparison is made with data for a localized heat input zone. Agreement between the theory and the model is good. This model can be used for design purposes if a boiling correlation is available. The model can be extended to provide improved predictions of heat pipe performance

Global transcriptome analysis of the heat shock response ofshewanella oneidensis

Energy Technology Data Exchange (ETDEWEB)

Gao, Haichun; Wang, Sarah; Liu, Xueduan; Yan, Tinfeng; Wu, Liyou; Alm, Eric; Arkin, Adam P.; Thompson, Dorothea K.; Zhou, Jizhong

2004-04-30

Shewanella oneidensis is an important model organism for bioremediation studies because of its diverse respiratory capabilities. However, the genetic basis and regulatory mechanisms underlying the ability of S. oneidensis to survive and adapt to various environmentally relevant stresses is poorly understood. To define this organism's molecular response to elevated growth temperatures, temporal gene expression profiles were examined in cells subjected to heat stress using whole-genome DNA microarrays for S. oneidensis MR-1. Approximately 15 percent (711) of the predicted S. oneidensis genes represented on the microarray were significantly up- or down-regulated (P < 0.05) over a 25-min period following shift to the heat shock temperature (42 C). As expected, the majority of S. oneidensis genes exhibiting homology to known chaperones and heat shock proteins (Hsps) were highly and transiently induced. In addition, a number of predicted genes encoding enzymes in glycolys is and the pentose cycle, [NiFe] dehydrogenase, serine proteases, transcriptional regulators (MerR, LysR, and TetR families), histidine kinases, and hypothetical proteins were induced in response to heat stress. Genes encoding membrane proteins were differentially expressed, suggesting that cells possibly alter their membrane composition or structure in response to variations in growth temperature. A substantial number of the genes encoding ribosomal proteins displayed down-regulated co-expression patterns in response to heat stress, as did genes encoding prophage and flagellar proteins. Finally, based on computational comparative analysis of the upstream promoter regions of S.oneidensis heat-inducible genes, a putative regulatory motif, showing high conservation to the Escherichia coli sigma 32-binding consensus sequence, was identified.

Experimental study of the structure of vapor phase during boiling of R134a on heat exchange surfaces of heat pump

Science.gov (United States)

Ustinov, D. A.; Sukhikh, A. A.; Sidenkov, D. V.; Ustinov, V. A.

2017-10-01

The heat supply by means of heat pumps is considered now as a rational method of local heating which can lead to economy of primary fuel. At use of low-potential heat, for example, the heat of a ground (5 … 18 °C) or ground waters (8 … 10°C) only small depressing of temperature of these sources (on 3 … 5°C) is possible that demands application of heat exchangers with intensified heatmass transfer surfaces. In thermal laboratory of TOT department the 200 W experimental installation has been developed for research of process of boiling of freon R134a. The principle of action of the installation consists in realisation of reverse thermodynamic cycle and consecutive natural measurement of characteristics of elements of surfaces of heat exchangers of real installations at boiling points of freon from-10°C to +10°C and condensing temperatures from 15°C to 50 °C. The evaporator casing has optical windows for control of process of boiling of freon on ribbed on technology of distorting cut tubes. Temperature measurement in characteristic points of a cycle is provided by copper-constantan thermocouples which by means of ADT are connected to the computer that allows treat results of measurements in a real time mode. The structure of a two-phase flow investigated by means of the optical procedure based on laser technique.

The study of the heat-engineering characteristics of a solar heat collector based on aluminum heat pipes

International Nuclear Information System (INIS)

Khairnasov, S.M.; Zaripov, V.K.; Passamakin, B.M. et al.

2013-01-01

This paper presents the results of studies into the heat-engineering characteristics of a flat heat solar collector based on aluminum heat pipes that is designed to be used in building facades. The principle of work and the structure of the solar collector are considered; the results of its comparison with a traditional flat solar collector are presented. The studies were performed at a heat carrier temperature range of +10 - +30 degree C and at a solar heat flow density of 400 - 1000 W/m 2 . The obtained experimental heat-engineering characteristics of the collector based on heat pipes show that they are at a level of traditional flow solar collectors; for example, its efficiency is 0.65 - 0.73. Meanwhile, the hydraulic resistance of the structure with heat pipes is by a factor of 2 - 2.4 smaller and ensures a high level of scalability, reliability, and maintainability, which is important when using it as an element of facade constructions of solar heat systems. (author)

Uncertainties in the estimation of specific absorption rate during radiofrequency alternating magnetic field induced non-adiabatic heating of ferrofluids

Science.gov (United States)

Lahiri, B. B.; Ranoo, Surojit; Philip, John

2017-11-01

Magnetic fluid hyperthermia (MFH) is becoming a viable cancer treatment methodology where the alternating magnetic field induced heating of magnetic fluid is utilized for ablating the cancerous cells or making them more susceptible to the conventional treatments. The heating efficiency in MFH is quantified in terms of specific absorption rate (SAR), which is defined as the heating power generated per unit mass. In majority of the experimental studies, SAR is evaluated from the temperature rise curves, obtained under non-adiabatic experimental conditions, which is prone to various thermodynamic uncertainties. A proper understanding of the experimental uncertainties and its remedies is a prerequisite for obtaining accurate and reproducible SAR. Here, we study the thermodynamic uncertainties associated with peripheral heating, delayed heating, heat loss from the sample and spatial variation in the temperature profile within the sample. Using first order approximations, an adiabatic reconstruction protocol for the measured temperature rise curves is developed for SAR estimation, which is found to be in good agreement with those obtained from the computationally intense slope corrected method. Our experimental findings clearly show that the peripheral and delayed heating are due to radiation heat transfer from the heating coils and slower response time of the sensor, respectively. Our results suggest that the peripheral heating is linearly proportional to the sample area to volume ratio and coil temperature. It is also observed that peripheral heating decreases in presence of a non-magnetic insulating shielding. The delayed heating is found to contribute up to ~25% uncertainties in SAR values. As the SAR values are very sensitive to the initial slope determination method, explicit mention of the range of linear regression analysis is appropriate to reproduce the results. The effect of sample volume to area ratio on linear heat loss rate is systematically studied and the

Uncertainties in the estimation of specific absorption rate during radiofrequency alternating magnetic field induced non-adiabatic heating of ferrofluids

International Nuclear Information System (INIS)

Lahiri, B B; Ranoo, Surojit; Philip, John

2017-01-01

Magnetic fluid hyperthermia (MFH) is becoming a viable cancer treatment methodology where the alternating magnetic field induced heating of magnetic fluid is utilized for ablating the cancerous cells or making them more susceptible to the conventional treatments. The heating efficiency in MFH is quantified in terms of specific absorption rate (SAR), which is defined as the heating power generated per unit mass. In majority of the experimental studies, SAR is evaluated from the temperature rise curves, obtained under non-adiabatic experimental conditions, which is prone to various thermodynamic uncertainties. A proper understanding of the experimental uncertainties and its remedies is a prerequisite for obtaining accurate and reproducible SAR. Here, we study the thermodynamic uncertainties associated with peripheral heating, delayed heating, heat loss from the sample and spatial variation in the temperature profile within the sample. Using first order approximations, an adiabatic reconstruction protocol for the measured temperature rise curves is developed for SAR estimation, which is found to be in good agreement with those obtained from the computationally intense slope corrected method. Our experimental findings clearly show that the peripheral and delayed heating are due to radiation heat transfer from the heating coils and slower response time of the sensor, respectively. Our results suggest that the peripheral heating is linearly proportional to the sample area to volume ratio and coil temperature. It is also observed that peripheral heating decreases in presence of a non-magnetic insulating shielding. The delayed heating is found to contribute up to ∼25% uncertainties in SAR values. As the SAR values are very sensitive to the initial slope determination method, explicit mention of the range of linear regression analysis is appropriate to reproduce the results. The effect of sample volume to area ratio on linear heat loss rate is systematically studied and

Deceleration of arginine kinase refolding by induced helical structures.

Science.gov (United States)

Li, Hai-Long; Zhou, Sheng-Mei; Park, Daeui; Jeong, Hyoung Oh; Chung, Hae Young; Yang, Jun-Mo; Meng, Fan-Guo; Hu, Wei-Jiang

2012-04-01

Arginine kinase (AK) is a key metabolic enzyme for keeping energy balance in invertebrates. Therefore, regulation of the enzymatic activity and the folding studies of AK from the various invertebrates have been the focus of investigation. We studied the effects of helical structures by using hexafluoroisopropanol (HFIP) on AK folding. Folding kinetic studies showed that the folding rates of the urea-denatured AKs were significantly decelerated after being induced in various concentrations of HFIP. AK lost its activity completely at concentrations greater than 60%. The results indicated that the HFIP-induced helical structures in the denatured state play a negative role in protein folding, and the helical structures induced in 5% (v/v) HFIP act as the most effective barrier against AK taking its native structure. The computational docking simulations (binding energies for -2.19 kcal/mol for AutoDock4.2 and -20.47 kcal/mol for Dock6.3) suggested that HFIP interacts with the several important residues that are predicted by both programs. The excessively pre-organized helical structures not only hampered the folding process, but also ultimately brought about changes in the three-dimensional conformation and biological function of AK.

Experimental investigation of the effects of heat release on mixing processes and flow structure in a high-speed subsonic turbulent H{sub 2} jet

Energy Technology Data Exchange (ETDEWEB)

Theron, M.; Bellenoue, M. [Laboratoire de Combustion et de Detonique, CNRS UPR 9028, Poitiers (France)

2006-06-15

In this paper, we explore the effects of heat release on mixing and flow structure in a high-speed subsonic turbulent H{sub 2} jet in an air coflow. Heat release effects are determined from the comparison of nonreacting and reacting jet behavior, boundary conditions being identical in both cases. Experiments are performed in a wind tunnel specifically designed for this purpose. Planar laser induced fluorescence on OH radicals and on acetone (seeded in the hydrogen jet) are used to characterize the cartography of scalars, and laser Doppler velocimetry is used to characterize velocity profiles in the far field of the H{sub 2} jet. Results show significant effects of heat release on mixing and flow structure, indicating an overall reduction of mixing and entrainment in the reacting jet compared to the nonreacting jet. First, a change is observed in the orientation of coherent structures originating from Kelvin-Helmholtz type instabilities, and responsible for air entrainment within the jet, which appear 'flatter' in the jet flame. Then, the flame length is increased over what would be predicted from the intersection of the mean stoichiometric contour with the centerline of the nonreacting jet. And finally, the longitudinal average velocity decrease along the jet axis is quicker in the nonreacting jet, and nondimensional transverse velocity fluctuations are about half as high in the reacting jet as in the nonreacting jet, indicating a reduction of the turbulence intensity of the flow in this direction in the jet flame. (author)

Implantable polymer/metal thin film structures for the localized treatment of cancer by Joule heating

Science.gov (United States)

Kan-Dapaah, Kwabena; Rahbar, Nima; Theriault, Christian; Soboyejo, Wole

2015-04-01

This paper presents an implantable polymer/metal alloy thin film structure for localized post-operative treatment of breast cancer. A combination of experiments and models is used to study the temperature changes due to Joule heating by patterned metallic thin films embedded in poly-dimethylsiloxane. The heat conduction within the device and the surrounding normal/cancerous breast tissue is modeled with three-dimensional finite element method (FEM). The FEM simulations are used to explore the potential effects of device geometry and Joule heating on the temperature distribution and lesion (thermal dose). The FEM model is validated using a gel model that mimics biological media. The predictions are also compared to prior results from in vitro studies and relevant in vivo studies in the literature. The implications of the results are discussed for the potential application of polymer/metal thin film structures in hyperthermic treatment of cancer.

Heat transfer enhancement induced by electrically generated convection in a plane layer of dielectric liquid

International Nuclear Information System (INIS)

Traoré, P; Wu, J; Romat, H; Louste, C; Perez, A; Koulova, D

2012-01-01

The electro-thermo-convective motion in a plane horizontal dielectric liquid layer subjected to simultaneous action of electric field and thermal gradient is numerically investigated. We consider the case of a strong unipolar charge injection C = 10 from above or below. Therefore in this context, we only take into account the Coulomb force, disregarding the dielectric one. The effect of the electric field on the heat transfer is analyzed through the characterization of the time history of the Nusselt number as well as its evolution according to the characteristic dimensionless electric parameter T. It is demonstrated that the electric effects dominate the buoyancy ones resulting in an electrically induced convection which significantly enhance the heat transfer.

Nanoscale Structural and Mechanical Analysis of Bacillus anthracis Spores Inactivated with Rapid Dry Heating

Science.gov (United States)

Felker, Daniel L.; Burggraf, Larry W.

2014-01-01

Effective killing of Bacillus anthracis spores is of paramount importance to antibioterrorism, food safety, environmental protection, and the medical device industry. Thus, a deeper understanding of the mechanisms of spore resistance and inactivation is highly desired for developing new strategies or improving the known methods for spore destruction. Previous studies have shown that spore inactivation mechanisms differ considerably depending upon the killing agents, such as heat (wet heat, dry heat), UV, ionizing radiation, and chemicals. It is believed that wet heat kills spores by inactivating critical enzymes, while dry heat kills spores by damaging their DNA. Many studies have focused on the biochemical aspects of spore inactivation by dry heat; few have investigated structural damages and changes in spore mechanical properties. In this study, we have inactivated Bacillus anthracis spores with rapid dry heating and performed nanoscale topographical and mechanical analysis of inactivated spores using atomic force microscopy (AFM). Our results revealed significant changes in spore morphology and nanomechanical properties after heat inactivation. In addition, we also found that these changes were different under different heating conditions that produced similar inactivation probabilities (high temperature for short exposure time versus low temperature for long exposure time). We attributed the differences to the differential thermal and mechanical stresses in the spore. The buildup of internal thermal and mechanical stresses may become prominent only in ultrafast, high-temperature heat inactivation when the experimental timescale is too short for heat-generated vapor to efficiently escape from the spore. Our results thus provide direct, visual evidences of the importance of thermal stresses and heat and mass transfer to spore inactivation by very rapid dry heating. PMID:24375142

Fine structure in the inter-critical heat-affected zone of HQ130 super ...

Indian Academy of Sciences (India)

Unknown

†Key Laboratory of Liquid Structure and Heredity of Materials, Ministry of Education, ... The microstructure in the inter-critical heat-affected zone (ICHAZ) of HQ130 steel, has been .... Ac3. The microhardness was measured by using the.

[Effect of heat treatment on the structure of a Cu-Zn-Al-Ni system dental alloy].

Science.gov (United States)

Guastaldi, A C; Adorno, A T; Beatrice, C R; Mondelli, J; Ishikiriama, A; Lacefield, W

1990-01-01

This article characterizes the structural phases present in the copper-based metallic alloy system "Cu-Zn-Al-Ni" developed for dental use, and relates those phases to other properties. The characterization was obtained after casting (using the lost wax process), and after heat treatment. In order to obtain better corrosion resistance by changing the microstructure, the castings were submitted to 30, 45 and 60 minutes of heat treatment at the following temperatures: 750 degrees C, 800 degrees C, and 850 degrees C. The various phases were analyzed using X-ray diffraction and scanning electron microscopy (SEM). The results after heat treatment showed a phase (probably Cu3Al), that could be responsible for the improvement in the alloy's resistance to corrosion as compared to the as-cast structure.

Magnetic susceptibility, specific heat and magnetic structure of CuNi2(PO4)2

International Nuclear Information System (INIS)

Escobal, Jaione; Pizarro, Jose L.; Mesa, Jose L.; Larranaga, Aitor; Fernandez, Jesus Rodriguez; Arriortua, Maria I.; Rojo, Teofilo

2006-01-01

The CuNi 2 (PO 4 ) 2 phosphate has been synthesized by the ceramic method at 800 deg. C in air. The crystal structure consists of a three-dimensional skeleton constructed from MO 4 (M II =Cu and Ni) planar squares and M 2 O 8 dimers with square pyramidal geometry, which are interconnected by (PO 4 ) 3- oxoanions with tetrahedral geometry. The magnetic behavior has been studied on powdered sample by using susceptibility, specific heat and neutron diffraction data. The bimetallic copper(II)-nickel(II) orthophosphate exhibits a three-dimensional magnetic ordering at, approximately, 29.8 K. However, its complex crystal structure hampers any parametrization of the J-exchange parameter. The specific heat measurements exhibit a three-dimensional magnetic ordering (λ-type) peak at 29.5 K. The magnetic structure of this phosphate shows ferromagnetic interactions inside the Ni 2 O 8 dimers, whereas the sublattice of Cu(II) ions presents antiferromagnetic couplings along the y-axis. The change of the sign in the magnetic unit-cell, due to the [1/2, 0, 1/2] propagation vector determines a purely antiferromagnetic structure. - Graphical abstract: Magnetic structure of CuNi2(PO4)2

Shear-induced nano-macro structural transition in a polymeric bicontinuous microemulsion

DEFF Research Database (Denmark)

Krishnan, K.; Almdal, K.; Burghardt, W.R.

2001-01-01

structure. In situ neutron scattering shows flow-induced anisotropy in the nanometer-scale microemulsion structure at moderate shear rates, while higher rates induce bulk phase separation, with micron-size morphology, which is characterized with in situ light scattering and optical microscopy....

A study on the flow induced vibration in two phase flow under heating and non-heating conditions

International Nuclear Information System (INIS)

Kim, Dae Hun

2007-02-01

Critical heat flux (CHF) enhancement devices, like a spacer grid with mixing vane, cause flow-induced vibration (FIV) due to turbulence made by structural resistance. CHF enhancement and FIV reduction are usually studied separately. The main purpose of this article is to investigate the relationship between CHF and FIV. Information of flow-induced vibration due to wire coil design, is experimentally presented in this study by detecting flow-induced vibration under the two-phase flow condition with wire coil inserts. CHF experiments were performed in an upward vertical annulus tube under controlled vibration conditions to determine the effect of vibration on CHF. FIV was measured in an upward vertical tube with various wire coil inserts using air-water as flow material. CHF experiments were performed at one atmosphere with mechanically controlled vibration. A quartz tube (inner diameter of 17 mm, thickness of 2mm and length of 0.72 m) was used for outer tube and a SUS-304 tube (outer diameter of 6.35 mm, thickness of 0.89 mm and length of 0.7 m) was used for the inner heater. Vibration of the heater tube with an amplitude range of 0.1 mm to 0.5 mm and a frequency range of 10 Hz to 50 Hz was carried out at a mass flux of 115 kg/m 2 s and 215 kg/m 2 s. CHF was enhanced by vibration with a maximum ratio of 16.4 %. CHF was increased with increased amplitude and quality. The CHF correlation was developed with R (coefficient of correlation) of 0.903. FIV measuring experiments were performed at one atmosphere by changing the inserted wire coil type. An acrylic tube was used for the test section with inner diameter of 25 mm, thickness of 10 mm and length of 0.5 m. Four types of wire coil, which have a thickness of between 2 mm and 3 mm and pitch length of between 25 mm and 50 mm, were used. FIV and dynamic pressure were detected in water mass flux range of 100 ∼ 3060 kg/m 2 s and air mass flux range of 5.02 ∼ 60.3 kg/m 2 s. Vibration increased along with mass flux and

Diffusion induced nuclear reactions in metals: a possible source of heat in the core

International Nuclear Information System (INIS)

Hamza, V.M.; Iyer, S.S.S.

1989-01-01

It has recently been proposed that diffusion of light nuclei in metals can give rise to unusual electrical charge distributions in their lattice structures, inducing thereby certain nuclear reactions that are otherwise uncommon. In the light of these results we advance the hypothesis that such nuclear reactions take place in the metal rich core of the earth, based on following observations: 1 - The solubility of hydrogen in metals is relatively high compared to that in silicates. 2 - Studies of rare gas samples in intraplate volcanos and diamonds show that 3 He/ He ratio increases with depth in the mantle. 3 - There are indications that He is positively correlated with enrichment of metals in lavas. We propose that hydrogen incorporated into metallic phases at the time of planetary accretion was carried to the core by downward migration of metal rich melts during the early states of proto-earth. Preliminary estimates suggest that cold fusion reactions can give rise to an average rate of heat generation of 8.2x10 12 W and may thus serve as a supplementary source of energy for the geomagnetic dynamo. (author)

Specific heat, polarization and heat conduction in microwave heating systems: A nonequilibrium thermodynamic point of view

International Nuclear Information System (INIS)

Bergese, Paolo

2006-01-01

A microwave (MW) field can induce in a dielectric material an oscillatory polarization. By this mechanism part of the energy carried by the waves is converted into chaotic agitation, and the material heats up. MW heating is a nonequilibrium phenomenon, while conventional heating can generally be considered as quasi-static. Excess (or nonthermal) effects of MWs with respect to conventional heating lie in this difference. Macroscopically, MW heating can be described in the framework of linear nonequilibrium thermodynamics (NET). This approach indicates that in a dielectric material under MW heating the specific heat has a dynamic component linked to the variation of polarization with temperature, and that polarization and heat conduction are intertwined. In particular, linear NET provides a new phenomenological equation for heat conduction that is composed of the classic Fourier's law and an additional term due to polarization relaxation. This term quantitatively describes the excess effect of MWs on thermal conduction

Parallel Changes in H2O2 and Catalase during Thermotolerance Induced by Salicylic Acid or Heat Acclimation in Mustard Seedlings1

Science.gov (United States)

Dat, James F.; Lopez-Delgado, Humberto; Foyer, Christine H.; Scott, Ian M.

1998-01-01

Spraying mustard (Sinapis alba L.) seedlings with salicylic acid (SA) solutions between 10 and 500 μm significantly improved their tolerance to a subsequent heat shock at 55°C for 1.5 h. The effects of SA were concentration dependent, with higher concentrations failing to induce thermotolerance. The time course of thermotolerance induced by 100 μm SA was similar to that obtained with seedlings acclimated at 45°C for 1 h. We examined the hypothesis that induced thermotolerance involved H2O2. Heat shock at 55°C caused a significant increase in endogenous H2O2 and reduced catalase activity. A peak in H2O2 content was observed within 5 min of either SA treatment or transfer to the 45°C acclimation temperature. Between 2 and 3 h after SA treatment or heat acclimation, both H2O2 and catalase activity significantly decreased below control levels. The lowered H2O2 content and catalase activity occurred in the period of maximum thermoprotection. It is suggested that thermoprotection obtained either by spraying SA or by heat acclimation may be achieved by a common signal transduction pathway involving an early increase in H2O2. PMID:9536052

Silver nanoparticles induced heat shock protein 70, oxidative stress and apoptosis in Drosophila melanogaster.

Science.gov (United States)

Ahamed, Maqusood; Posgai, Ryan; Gorey, Timothy J; Nielsen, Mark; Hussain, Saber M; Rowe, John J

2010-02-01

Due to the intensive commercial application of silver nanoparticles (Ag NPs), risk assessment of this nanoparticle is of great importance. Our previous in vitro study demonstrated that Ag NPs caused DNA damage and apoptosis in mouse embryonic stem cells and fibroblasts. However, toxicity of Ag NPs in vivo is largely lacking. This study was undertaken to examine the toxic effects of well-characterized polysaccharide coated 10 nm Ag NPs on heat shock stress, oxidative stress, DNA damage and apoptosis in Drosophila melanogaster. Third instar larvae of D. melanogaster were fed a diet of standard cornmeal media mixed with Ag NPs at the concentrations of 50 and 100 microg/ml for 24 and 48 h. Ag NPs up-regulated the expression of heat shock protein 70 and induced oxidative stress in D. melanogaster. Malondialdehyde level, an end product of lipid peroxidation was significantly higher while antioxidant glutathione content was significantly lower in Ag NPs exposed organisms. Activities of antioxidant enzyme superoxide dismutase and catalase were also significantly higher in the organisms exposed to Ag NPs. Furthermore, Ag NPs up-regulated the cell cycle checkpoint p53 and cell signaling protein p38 that are involved in the DNA damage repair pathway. Moreover, activities of caspase-3 and caspase-9, markers of apoptosis were significantly higher in Ag NPs exposed organisms. The results indicate that Ag NPs in D. melanogaster induce heat shock stress, oxidative stress, DNA damage and apoptosis. This study suggests that the organism is stressed and thus warrants more careful assessment of Ag NPs using in vivo models to determine if chronic exposure presents developmental and reproductive toxicity. Copyright 2009 Elsevier Inc. All rights reserved.

Silver nanoparticles induced heat shock protein 70, oxidative stress and apoptosis in Drosophila melanogaster

International Nuclear Information System (INIS)

Ahamed, Maqusood; Posgai, Ryan; Gorey, Timothy J.; Nielsen, Mark; Hussain, Saber M.; Rowe, John J.

2010-01-01

Due to the intensive commercial application of silver nanoparticles (Ag NPs), risk assessment of this nanoparticle is of great importance. Our previous in vitro study demonstrated that Ag NPs caused DNA damage and apoptosis in mouse embryonic stem cells and fibroblasts. However, toxicity of Ag NPs in vivo is largely lacking. This study was undertaken to examine the toxic effects of well-characterized polysaccharide coated 10 nm Ag NPs on heat shock stress, oxidative stress, DNA damage and apoptosis in Drosophila melanogaster. Third instar larvae of D. melanogaster were fed a diet of standard cornmeal media mixed with Ag NPs at the concentrations of 50 and 100 μg/ml for 24 and 48 h. Ag NPs up-regulated the expression of heat shock protein 70 and induced oxidative stress in D. melanogaster. Malondialdehyde level, an end product of lipid peroxidation was significantly higher while antioxidant glutathione content was significantly lower in Ag NPs exposed organisms. Activities of antioxidant enzyme superoxide dismutase and catalase were also significantly higher in the organisms exposed to Ag NPs. Furthermore, Ag NPs up-regulated the cell cycle checkpoint p53 and cell signaling protein p38 that are involved in the DNA damage repair pathway. Moreover, activities of caspase-3 and caspase-9, markers of apoptosis were significantly higher in Ag NPs exposed organisms. The results indicate that Ag NPs in D. melanogaster induce heat shock stress, oxidative stress, DNA damage and apoptosis. This study suggests that the organism is stressed and thus warrants more careful assessment of Ag NPs using in vivo models to determine if chronic exposure presents developmental and reproductive toxicity.

A Calculation of Nuclear Heating by Activation Product of Structure Materials for the In-core Irradiation Hole in the HANARO

International Nuclear Information System (INIS)

Noh, Tae Yang; Park, B. G.; Kim, M. S.

2016-01-01

Only delayed gamma heating is considered in this paper. Contribution of the delayed gamma heating is expected to be negligible for the reactor power. For the neutron irradiation, however, the contribution of delayed gamma heating is not negligible issue, and it should be evaluated for safety analysis. Additionally, in the case of temperature-sensitive irradiation targets, the delayed gamma heating should be evaluated precisely. For the HANARO, the delayed gamma heating has been evaluated by modifying the library data of the calculation code or by assuming the heating to be conservative value based on prompt gamma heating. For the method of modifying the library data, however, it should be able to estimate isotopes which contribute to heat generation exactly. And furthermore, it should be concerned to determine modified emission yield of gamma-rays depending on the half-life. For the method of assuming conservative value, it is hard to determine whether the assumed heating value is enough conservative or not. In this study, a methodology for evaluation of nuclear heating by structure materials irradiated for a long time is established with the ORIGEN and MCNP codes. And this method is applied to determine the nuclear heating of the RI capsule in the IR2 irradiation hole in the HANARO. In this paper, the methodology for evaluation of heat generation by irradiated structure materials was established by using the ORIGEN and MCNP codes. From this result, the contribution by farther structures was expected to be negligible. Meanwhile, heat generation by delayed gamma-ray was calculated less than 0.03% of heat generation by prompt radiations. The result of this study indicates that there are some remaining issues for the real situation of the neutron irradiation at HANARO.