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Sample records for healthcare challenges opportunities

  1. Challenges and Opportunities in Scaling-Up Nutrition in Healthcare

    OpenAIRE

    Darnton-Hill, Ian; Samman, Samir

    2015-01-01

    Healthcare continues to be in a state of flux; conventionally, this provides opportunities and challenges. The opportunities include technological breakthroughs, improved economies and increasing availability of healthcare. On the other hand, economic disparities are increasing and leading to differing accessibility to healthcare, including within affluent countries. Nutrition has received an increase in attention and resources in recent decades, a lot of it stimulated by the rise in obesity,...

  2. Challenges and Opportunities in Scaling-Up Nutrition in Healthcare

    Directory of Open Access Journals (Sweden)

    Ian Darnton-Hill

    2015-01-01

    Full Text Available Healthcare continues to be in a state of flux; conventionally, this provides opportunities and challenges. The opportunities include technological breakthroughs, improved economies and increasing availability of healthcare. On the other hand, economic disparities are increasing and leading to differing accessibility to healthcare, including within affluent countries. Nutrition has received an increase in attention and resources in recent decades, a lot of it stimulated by the rise in obesity, type 2 diabetes mellitus and hypertension. An increase in ageing populations also has meant increased interest in nutrition-related chronic diseases. In many middle-income countries, there has been an increase in the double burden of malnutrition with undernourished children and overweight/obese parents and adolescents. In low-income countries, an increased evidence base has allowed scaling-up of interventions to address under-nutrition, both nutrition-specific and nutrition-sensitive interventions. Immediate barriers (institutional, structural and biological and longer-term barriers (staffing shortages where most needed and environmental impacts on health are discussed. Significant barriers remain for the near universal access to healthcare, especially for those who are socio-economically disadvantaged, geographically isolated, living in war zones or where environmental damage has taken place. However, these barriers are increasingly being recognized, and efforts are being made to address them. The paper aims to take a broad view that identifies and then comments on the many social, political and scientific factors affecting the achievement of improved nutrition through healthcare.

  3. Data-Driven Healthcare: Challenges and Opportunities for Interactive Visualization.

    Science.gov (United States)

    Gotz, David; Borland, David

    2016-01-01

    The healthcare industry's widespread digitization efforts are reshaping one of the largest sectors of the world's economy. This transformation is enabling systems that promise to use ever-improving data-driven evidence to help doctors make more precise diagnoses, institutions identify at risk patients for intervention, clinicians develop more personalized treatment plans, and researchers better understand medical outcomes within complex patient populations. Given the scale and complexity of the data required to achieve these goals, advanced data visualization tools have the potential to play a critical role. This article reviews a number of visualization challenges unique to the healthcare discipline.

  4. Deep learning for healthcare: review, opportunities and challenges.

    Science.gov (United States)

    Miotto, Riccardo; Wang, Fei; Wang, Shuang; Jiang, Xiaoqian; Dudley, Joel T

    2017-05-06

    Gaining knowledge and actionable insights from complex, high-dimensional and heterogeneous biomedical data remains a key challenge in transforming health care. Various types of data have been emerging in modern biomedical research, including electronic health records, imaging, -omics, sensor data and text, which are complex, heterogeneous, poorly annotated and generally unstructured. Traditional data mining and statistical learning approaches typically need to first perform feature engineering to obtain effective and more robust features from those data, and then build prediction or clustering models on top of them. There are lots of challenges on both steps in a scenario of complicated data and lacking of sufficient domain knowledge. The latest advances in deep learning technologies provide new effective paradigms to obtain end-to-end learning models from complex data. In this article, we review the recent literature on applying deep learning technologies to advance the health care domain. Based on the analyzed work, we suggest that deep learning approaches could be the vehicle for translating big biomedical data into improved human health. However, we also note limitations and needs for improved methods development and applications, especially in terms of ease-of-understanding for domain experts and citizen scientists. We discuss such challenges and suggest developing holistic and meaningful interpretable architectures to bridge deep learning models and human interpretability. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  5. Using Linked Electronic Health Records to Estimate Healthcare Costs: Key Challenges and Opportunities.

    Science.gov (United States)

    Asaria, Miqdad; Grasic, Katja; Walker, Simon

    2016-02-01

    This paper discusses key challenges and opportunities that arise when using linked electronic health records (EHR) in health economics and outcomes research (HEOR), with a particular focus on estimating healthcare costs. These challenges and opportunities are framed in the context of a case study modelling the costs of stable coronary artery disease in England. The challenges and opportunities discussed fall broadly into the categories of (1) handling and organising data of this size and sensitivity; (2) extracting clinical endpoints from datasets that have not been designed and collected with such endpoints in mind; and (3) the principles and practice of costing resource use from routinely collected data. We find that there are a number of new challenges and opportunities that arise when working with EHR compared with more traditional sources of data for HEOR. These call for greater clinician involvement and intelligent use of sensitivity analysis.

  6. Crowdsourcing healthcare costs: Opportunities and challenges for patient centered price transparency.

    Science.gov (United States)

    Meisel, Zachary F; VonHoltz, Lauren A Houdek; Merchant, Raina M

    2016-03-01

    Efforts to improve health care price transparency have garnered significant attention from patients, policy makers, and health insurers. In response to increasing consumer demand, state governments, insurance plans, and health care providers are reporting health care prices. However, such data often do not provide consumers with the most salient information: their own actual out-of-pocket cost for medical care. Although untested, crowdsourcing, a mechanism for the public to help answer complex questions, represents a potential solution to the problem of opaque hospital costs. This article explores, the challenges and potential opportunities for crowdsourcing out-of-pocket costs for healthcare consumers. Copyright © 2015 Elsevier Inc. All rights reserved.

  7. Methodological challenges and analytic opportunities for modeling and interpreting Big Healthcare Data.

    Science.gov (United States)

    Dinov, Ivo D

    2016-01-01

    Managing, processing and understanding big healthcare data is challenging, costly and demanding. Without a robust fundamental theory for representation, analysis and inference, a roadmap for uniform handling and analyzing of such complex data remains elusive. In this article, we outline various big data challenges, opportunities, modeling methods and software techniques for blending complex healthcare data, advanced analytic tools, and distributed scientific computing. Using imaging, genetic and healthcare data we provide examples of processing heterogeneous datasets using distributed cloud services, automated and semi-automated classification techniques, and open-science protocols. Despite substantial advances, new innovative technologies need to be developed that enhance, scale and optimize the management and processing of large, complex and heterogeneous data. Stakeholder investments in data acquisition, research and development, computational infrastructure and education will be critical to realize the huge potential of big data, to reap the expected information benefits and to build lasting knowledge assets. Multi-faceted proprietary, open-source, and community developments will be essential to enable broad, reliable, sustainable and efficient data-driven discovery and analytics. Big data will affect every sector of the economy and their hallmark will be 'team science'.

  8. Police on the Front Line of Community Geriatric Healthcare: Challenges and Opportunities

    Science.gov (United States)

    Brown, Rebecca T.; Ahalt, Cyrus; Steinman, Michael A.; Kruger, Kelly; Williams, Brie A.

    2015-01-01

    As the population ages, police increasingly serve as first responders to incidents involving older adults in which aging-related health plays a critical role. The goals of this study were to assess police officers’ knowledge of aging-related health; to identify challenges police experience in their encounters with older adults; and to describe their recommendations for how to address those challenges. This was a mixed methods study of 141 San Francisco police officers recruited from mandatory police trainings between 2011 and 2013. Descriptive statistics were used to analyze 141 self-administered questionnaires and principles of grounded theory were used to analyze open-ended questionnaire responses and 11 additional qualitative interviews. Nearly all officers (89%) reported interacting with older adults at least monthly. Although 84% of police reported prior training in working with older adults, only 32% rated themselves knowledgeable about aging-related health. Participants described themselves as first-responders to medical and social emergencies involving older adults and identified several challenges including identifying and responding to aging-related conditions and ensuring appropriate medical and social service hand-offs. To address these challenges, officers recommended developing trainings focused on recognizing and responding to aging-related conditions and improving police knowledge of community resources for older adults. They also called for enhanced communication and collaboration between police and clinicians. These findings suggest that despite playing a front-line role in responding to older adults with complex medical and social needs, many police may benefit from additional knowledge about aging-related health and community resources. Collaboration between police and healthcare providers presents an important opportunity to develop geriatrics training and interprofessional systems of care to support police work with a rapidly aging

  9. Role of in-situ simulation for training in healthcare: opportunities and challenges.

    Science.gov (United States)

    Kurup, Viji; Matei, Veronica; Ray, Jessica

    2017-12-01

    Simulation has now been acknowledged as an important part of training in healthcare, and most academic hospitals have a dedicated simulation center. In-situ simulation occurs in patient care units with scenarios involving healthcare professionals in their actual working environment. The purpose of this review is to describe the process of putting together the components of in-situ simulation for training programs and to review outcomes studied, and challenges with this approach. In-situ simulation has been used to 'test-drive' new centers, train personnel in new procedures in existing centers, for recertification training and to uncover latent threats in clinical care areas. It has also emerged as an attractive alternative to traditional simulations for institutions that do not have their own simulation center. In-situ simulation can be used to improve reliability and safety especially in areas of high risk, and in high-stress environments. It is also a reasonable and attractive alternative for programs that want to conduct interdisciplinary simulations for their trainees and faculty, and for those who do not have access to a fully functional simulation center. Further research needs to be done in assessing effectiveness of training using this method and the effect of such training on clinical outcomes.

  10. Panoramic view of challenges and opportunities for primary healthcare systems in Pakistan

    International Nuclear Information System (INIS)

    Sharif, H.; Sughra, U.; Butt, Z.

    2016-01-01

    Pakistan has a broad system of primary health care facilities to achieve mission of Health for all. Over the last seven years health expenditure by government of Pakistan has been increased to attain this goal. This study was conducted with the aim to assess all blocks of service readiness (basic equipment, basic amenities, laboratory capacity, standard precautions and essential medicines) in public-primary health care facilities of tehsil Rawalpindi, Pakistan. Methods: A cross-sectional survey was carried out utilizing two separate structured questionnaires for basic health units and rural health centres. Information was collected from administrative heads along with other staff where required, of all public-primary health care facilities of Tehsil Rawalpindi. Data were analysed by using SPSS version17. Results: A total of 26 health facilities were assessed; only 56% BHUs had a sign board that was available in readable form. BHUs with women medical officer as administrative head constituted 52%. Backup for electricity and toilet were the most neglected areas. Basic amenities, standard precautions and laboratory capacity of Basic Health Units (BHUs) showed a clear deviation from standards and is thus a challenge for Pakistan's Primary Health care (PHC). On the other hand for Rural Health Centres (RHCs), most were on the way to meet expectations. Conclusion: Pakistan's government is undoubtedly putting efforts in order to achieve targets of primary healthcare but it needs better mainstreaming of political, institutional and social commitments with modified standards for PHC. (author)

  11. The development of safety cases for healthcare services: Practical experiences, opportunities and challenges

    International Nuclear Information System (INIS)

    Sujan, Mark; Spurgeon, Peter; Cooke, Matthew; Weale, Andy; Debenham, Philip; Cross, Steve

    2015-01-01

    There has been growing interest in the concept of safety cases for medical devices and health information technology, but questions remain about how safety cases can be developed and used meaningfully in the safety management of healthcare services and processes. The paper presents two examples of the development and use of safety cases at a service level in healthcare. These first practical experiences at the service level suggest that safety cases might be a useful tool to support service improvement and communication of safety in healthcare. The paper argues that safety cases might be helpful in supporting healthcare organisations with the adoption of proactive and rigorous safety management practices. However, it is also important to consider the different level of maturity of safety management and regulatory oversight in healthcare. Adaptations to the purpose and use of safety cases might be required, complemented by the provision of education to both practitioners and regulators. - Highlights: • Empirical description of safety case development at service level in healthcare. • Safety cases can support adoption of proactive and rigorous safety management. • Adaptation to purpose and use of safety cases might be required in healthcare. • Education should be provided to practitioners and regulators

  12. Collaboration and Co-Production of Knowledge in Healthcare: Opportunities and Challenges

    Directory of Open Access Journals (Sweden)

    Jo Rycroft-Malone

    2016-04-01

    Full Text Available Over time there has been a shift, at least in the rhetoric, from a pipeline conceptualisation of knowledge implementation, to one that recognises the potential of more collaboration, co-productive approaches to knowledge production and use. In this editorial, which is grounded in our research and collective experience, we highlight both the potential and challenge with collaboration and co-production. This includes issues about stakeholder engagement, governance arrangements, and capacity and capability for working in a coproductive way. Finally, we reflect on the fact that this approach is not a panacea, but is accompanied by some philosophical and practical challenges.

  13. Big Data: Challenge and Opportunity for Translational and Industrial Research in Healthcare

    Directory of Open Access Journals (Sweden)

    Riccardo L. Rossi

    2018-05-01

    Full Text Available Research and innovation are constant imperatives for the healthcare sector: medicine, biology and biotechnology support it, and more recently computational and data-driven disciplines gained relevance to handle the massive amount of data this sector is and will be generating. To be effective in translational and healthcare industrial research, big data in the life science domain need to be organized, well annotated, catalogued, correlated and integrated: the biggest the data silos at hand, the stronger the need for organization and tidiness. The degree of such organization marks the transition from data to knowledge for strategic decision making. Medicine is supported by observations and data and for certain aspects medicine is becoming a data science supported by clinicians. While medicine defines itself as personalized, quantified (precision med or in high-definition, clinicians should be prepared to deal with a world in which Internet of People paraphrases the Internet of Things paradigm. Integrated use of electronic health records (EHRs and quantitative data (both clinical and molecular is a key process to develop precision medicine. Health records collection was originally designed for patient care and billing and/or insurance purposes. The digitization of health records facilitates and opens up new possibilities for science and research and they should be now collected and managed with this aim in mind. More data and the ability to efficiently handle them is a significant advantage not only for clinicians and life science researchers, but for drugs producers too. In an industrial sector spending increasing efforts on drug repurposing, attention to efficient methods to unwind the intricacies of the hugely complex reality of human physiology, such as network based methods and physical chemistry computational methods, became of paramount importance. Finally, the main pillars of industrial R&D processes for vaccines, include initial discovery

  14. Dis-integration of communication in healthcare education: Workplace learning challenges and opportunities.

    Science.gov (United States)

    Rosenbaum, Marcy E

    2017-11-01

    The purpose of this paper, based on a 2016 Heidelberg International Conference on Communication in Healthcare (ICCH) plenary presentation, is to examine a key problem in communication skills training for health professional learners. Studies have pointed to a decline in medical students' communication skills and attitudes as they proceed through their education, particularly during their clinical workplace training experiences. This paper explores some of the key factors in this disintegration, drawing on selected literature and highlighting some curriculum efforts and research conducted at the University of Iowa Carver College of Medicine as a case study of these issues. Five key factors contributing to the disintegration of communication skills and attitudes are presented including: 1) lack of formal communication skills training during clinical clerkships; 2) informal workplace teaching failing to explicitly address learner clinical communication skills; 3) emphasizing content over process in relation to clinician-patient interactions; 4) the relationship between ideal communication models and the realities of clinical practice; and 5) clinical teachers' lack of knowledge and skills to effectively teach about communication in the clinical workplace. Within this discussion, potential practical responses by individual clinical teachers and broader curricular and faculty development efforts to address each of these factors are presented. Copyright © 2017 Elsevier B.V. All rights reserved.

  15. Approaches towards improving the quality of maternal and newborn health services in South Asia: challenges and opportunities for healthcare systems.

    Science.gov (United States)

    Mian, Naeem Uddin; Alvi, Muhammad Adeel; Malik, Mariam Zahid; Iqbal, Sarosh; Zakar, Rubeena; Zakar, Muhammad Zakria; Awan, Shehzad Hussain; Shahid, Faryal; Chaudhry, Muhammad Ashraf; Fischer, Florian

    2018-02-06

    South Asia is experiencing a dismal state of maternal and newborn health (MNH) as the region has been falling behind in reducing the levels of maternal and neonatal mortality. Most of the efforts are focused on enhancing coverage of MNH services; however, quality remains a serious concern if the region is to achieve expected outcomes in terms of standardised MNH services within healthcare delivery systems. This research consists of a review of South Asian quality improvement (QI) approaches/interventions, specifically implemented for MNH improvement. A literature review of QI approaches/interventions was conducted using the PRISMA guidelines. Online databases, including PubMed, the Cochrane Library and Google Scholar, were searched. Primary studies published between 1998 and 2013 were considered. Studies were initially screened and selected based upon the selection criteria for data extraction. A thematic synthesis/analysis was performed to organise, group and interpret the key findings according to prominent themes. Thirty studies from six South Asian countries were included in the review. Findings from these selected studies were grouped under eight broad, cross-cutting themes, which emerged from a deductive approach, representing the most commonly employed QI approaches for improving MNH services within different geographical settings. These consist of capacity building of healthcare providers on clinical quality, clinical audits and feedback, financial incentives to beneficiaries, pay-for-performance, supportive supervision, community engagement, collaborative efforts and multidimensional interventions. Employing and documenting QI approaches is essential in order to measure the potential of an intervention, considering its cost-effectiveness, feasibility and acceptability to communities. This research concluded that QI approaches are very diverse and cross-cutting, because they are subject to the varied requirements of regional health systems. This high level

  16. Patients as team members: opportunities, challenges and paradoxes of including patients in multi-professional healthcare teams.

    Science.gov (United States)

    Martin, Graham P; Finn, Rachael

    2011-11-01

    Current healthcare policy emphasises the need for more collaborative, team-based approaches to providing care, and for a greater voice for service users in the management and delivery of care. Increasingly, policy encourages 'partnerships' between users and professionals so that users, too, effectively become team members. In examining this phenomenon, this paper draws on insights from the organisational-sociological literature on team work, which highlights the challenges of bringing together diverse professional groups, but which has not, to date, been applied in contexts where users, too, are included in teams. Using data from a qualitative study of five pilot cancer-genetics projects, in which service users were included in teams responsible for managing and developing new services, it highlights the difficulties involved in making teams of such heterogeneous members-and the paradoxes that arise when this task is achieved. It reveals how the tension between integration and specialisation of team members, highlighted in the literature on teams in general, is especially acute for service users, the distinctiveness of whose contribution is more fragile, and open to blurring. © 2011 The Authors. Sociology of Health & Illness © 2011 Foundation for the Sociology of Health & Illness/Blackwell Publishing Ltd.

  17. Missed opportunities in child healthcare

    Directory of Open Access Journals (Sweden)

    Linda Jonker

    2014-01-01

    Full Text Available Background: Various policies in health, such as Integrated Management of Childhood Illnesses, were introduced to enhance integrated service delivery in child healthcare. During clinical practice the researcher observed that integrated services may not be rendered.Objectives: This article describes the experiences of mothers that utilised comprehensive child health services in the Cape Metropolitan area of South Africa. Services included treatment for diseases; preventative interventions such as immunisation; and promotive interventions, such as improvement in nutrition and promotion of breastfeeding.Method: A qualitative, descriptive phenomenological approach was applied to explore the experiences and perceptions of mothers and/or carers utilising child healthcare services. Thirty percent of the clinics were selected purposively from the total population. A convenience purposive non-probability sampling method was applied to select 17 mothers who met the criteria and gave written consent. Interviews were conducted and recorded digitally using an interview guide. The data analysis was done using Tesch’s eight step model.Results: Findings of the study indicated varied experiences. Not all mothers received information about the Road to Health book or card. According to the mothers, integrated child healthcare services were not practised. The consequences were missed opportunities in immunisation, provision of vitamin A, absence of growth monitoring, feeding assessment and provision of nutritional advice.Conclusion: There is a need for simple interventions such as oral rehydration, early recognition and treatment of diseases, immunisation, growth monitoring and appropriate nutrition advice. These services were not offered diligently. Such interventions could contribute to reducing the incidence of child morbidity and mortality.

  18. Missed opportunities in child healthcare

    Directory of Open Access Journals (Sweden)

    Linda Jonker

    2014-08-01

    Objectives: This article describes the experiences of mothers that utilised comprehensive child health services in the Cape Metropolitan area of South Africa. Services included treatment for diseases; preventative interventions such as immunisation; and promotive interventions, such as improvement in nutrition and promotion of breastfeeding. Method: A qualitative, descriptive phenomenological approach was applied to explore the experiences and perceptions of mothers and/or carers utilising child healthcare services. Thirty percent of the clinics were selected purposively from the total population. A convenience purposive non-probability sampling method was applied to select 17 mothers who met the criteria and gave written consent. Interviews were conducted and recorded digitally using an interview guide. The data analysis was done using Tesch’s eight step model. Results: Findings of the study indicated varied experiences. Not all mothers received information about the Road to Health book or card. According to the mothers, integrated child healthcare services were not practised. The consequences were missed opportunities in immunisation, provision of vitamin A, absence of growth monitoring, feeding assessment and provision of nutritional advice. Conclusion: There is a need for simple interventions such as oral rehydration, early recognition and treatment of diseases, immunisation, growth monitoring and appropriate nutrition advice. These services were not offered diligently. Such interventions could contribute to reducing the incidence of child morbidity and mortality.

  19. Challenges and opportunities

    International Nuclear Information System (INIS)

    Morgan, G.

    1998-01-01

    Challenges and opportunities facing the Canadian natural gas industry were discussed. The greatest opportunity is that the industry will become part of a fully functioning continental gas market for the first time in history. The challenge will be to ensure that the access to continental markets, which the Alliance project would provide, moves forward in a timely way, especially if the proposed merger between Canada's two dominant natural gas pipelines occurs. The second challenge is to find ways to deal with global warming in a more sensible and knowledgeable way. In the view of this author, the implications of the Kyoto greenhouse gas emission protocol could be potentially devastating to the competitiveness of the North American economy. According to the author, the emission stabilization policy will save the Earth only 0.05 degree C of warming in 2025 based on projected planetary temperature rise from 1990 to 2050. By 2050, the stabilization of emissions will have resulted in savings of only 0.10 degrees C, still a negligible amount. The impact of the Canadian Kyoto obligation was analyzed using federal Department of the Environment data. It was noted that in order for Canada to meet its commitment of reducing greenhouse gas emissions to 1990 levels by 6 per cent by 2008-2012, actual annual reduction in emission would have to amount to 20-25 per cent. To achieve that would require unimaginably drastic measures. 1 tab., 1 fig

  20. Ontology-Driven Knowledge-Based Health-Care System, An Emerging Area - Challenges And Opportunities - Indian Scenario

    Science.gov (United States)

    Sunitha, A.; Babu, G. Suresh

    2014-11-01

    Recent studies in the decision making efforts in the area of public healthcare systems have been tremendously inspired and influenced by the entry of ontology. Ontology driven systems results in the effective implementation of healthcare strategies for the policy makers. The central source of knowledge is the ontology containing all the relevant domain concepts such as locations, diseases, environments and their domain sensitive inter-relationships which is the prime objective, concern and the motivation behind this paper. The paper further focuses on the development of a semantic knowledge-base for public healthcare system. This paper describes the approach and methodologies in bringing out a novel conceptual theme in establishing a firm linkage between three different ontologies related to diseases, places and environments in one integrated platform. This platform correlates the real-time mechanisms prevailing within the semantic knowledgebase and establishing their inter-relationships for the first time in India. This is hoped to formulate a strong foundation for establishing a much awaited basic need for a meaningful healthcare decision making system in the country. Introduction through a wide range of best practices facilitate the adoption of this approach for better appreciation, understanding and long term outcomes in the area. The methods and approach illustrated in the paper relate to health mapping methods, reusability of health applications, and interoperability issues based on mapping of the data attributes with ontology concepts in generating semantic integrated data driving an inference engine for user-interfaced semantic queries.

  1. Engineering ethics challenges and opportunities

    CERN Document Server

    Bowen, W Richard

    2014-01-01

    Engineering Ethics: Challenges and Opportunities aims to set a new agenda for the engineering profession by developing a key challenge: can the great technical innovation of engineering be matched by a corresponding innovation in the acceptance and expression of ethical responsibility?  Central features of this stimulating text include:   ·         An analysis of engineering as a technical and ethical practice providing great opportunities for promoting the wellbeing and agency of individuals and communities. ·         Elucidation of the ethical opportunities of engineering in three key areas:             - Engineering for Peace, emphasising practical amelioration of the root causes of    conflict rather than military solutions.             - Engineering for Health, focusing on close collaboration with healthcare professionals      for both the promotion and restoration of health.             - Engineering for Development, providing effective solution...

  2. DIGITAL PAKISTAN: OPPORTUNITIES & CHALLENGES

    Directory of Open Access Journals (Sweden)

    Ghulam Muhammad Kundi

    2008-10-01

    Full Text Available IT has revolutionized the social and organizational life around the globe. Given the newness of IT as a technology, there is a lot of potential that needs to be explored. It is however, argued that as IT can revolutionize the economic development, by the same coin, although its mismanagement in adoption process can end up in problems or even straight failure of the technology at the business-end. This study was conducted with reference to opportunities and challenges in the IT adoption process in Pakistan. The aim of the study was to point out the barriers that are impeding the country’s computerization process in order to provide facts to the policy makers for smooth computerization. The primary data collected through structured questionnaires was analyzed and tested through correlation, regressions analysis and t-test. Out of 10 hypotheses, 3 were accepted while in the rest null hypotheses were not substantiated. Based on primary and secondary data analysis this study has found that all independent bureaucratic, political, education and social and cultural variables are mutually correlated and have significant impact on shaping and reshaping of IT in Pakistan, while the Pakistan IT policy is inconsistent, administrative machinery attitude is negative and non cooperative, procedures are cumbersome and implementation is weak and ineffective, not to mention the lack of IT knowledge on the bureaucratic side. The political environment is instable and law and order is worse which is discouraging the investment. Moreover, physical and legal infrastructure is insufficient and the country is lacking good quality IT professionals. IT organization alignment is another serious issue in Pakistan. However, government incentives and growing interest from the private sector indicate positive attitude towards computerization of the country.

  3. DIGITAL PAKISTAN: OPPORTUNITIES & CHALLENGES

    Directory of Open Access Journals (Sweden)

    Ghulam Muhammad Kundi

    2008-12-01

    Full Text Available ABSTRACT IT has revolutionized the social and organizational life around the globe. Given the newness of IT as a technology, there is a lot of potential that needs to be explored. It is however, argued that as IT can revolutionize the economic development, by the same coin, although its mismanagement in adoption process can end up in problems or even straight failure of the technology at the business-end. This study was conducted with reference to opportunities and challenges in the IT adoption process in Pakistan. The aim of the study was to point out the barriers that are impeding the country’s computerization process in order to provide facts to the policy makers for smooth computerization. The primary data collected through structured questionnaires was analyzed and tested through correlation, regressions analysis and t-test. Out of 10 hypotheses, 3 were accepted while in the rest null hypotheses were not substantiated. Based on primary and secondary data analysis this study has found that all independent bureaucratic, political, education and social and cultural variables are mutually correlated and have significant impact on shaping and reshaping of IT in Pakistan, while the Pakistan IT policy is inconsistent, administrative machinery attitude is negative and non cooperative, procedures are cumbersome and implementation is weak and ineffective, not to mention the lack of IT knowledge on the bureaucratic side. The political environment is instable and law and order is worse which is discouraging the investment. Moreover, physical and legal infrastructure is insufficient and the country is lacking good quality IT professionals. IT organization alignment is another serious issue in Pakistan. However, government incentives and growing interest from the private sector indicate positive attitude towards computerization of the country.

  4. Healthcare providers balancing norms and practice: challenges and opportunities in providing contraceptive counselling to young people in Uganda – a qualitative study

    Directory of Open Access Journals (Sweden)

    Mandira Paul

    2016-05-01

    Full Text Available Background: Pregnancies among young women force girls to compromise education, resulting in low educational attainment with subsequent poverty and vulnerability. A pronounced focus is needed on contraceptive use, pregnancy, and unsafe abortion among young women. Objective: This study aims to explore healthcare providers’ (HCPs perceptions and practices regarding contraceptive counselling to young people. Design: We conducted 27 in-depth interviews with doctors and midwives working in seven health facilities in central Uganda. Interviews were open-ended and allowed the participant to speak freely on certain topics. We used a topic guide to cover areas topics of interest focusing on post-abortion care (PAC but also covering contraceptive counselling. Transcripts were transcribed verbatim and data were analysed using thematic analysis. Results: The main theme, HCPs' ambivalence to providing contraceptive counselling to sexually active young people is based on two sub-themes describing the challenges of contraceptive counselling: A HCPs echo the societal norms regarding sexual practice among young people, while at the same time our findings B highlights the opportunities resulting from providers pragmatic approach to contraceptive counselling to young women. Providers expressed a self-identified lack of skill, limited resources, and inadequate support from the health system to successfully provide appropriate services to young people. They felt frustrated with the consultations, especially when meeting young women seeking PAC. Conclusions: Despite existing policies for young people's sexual and reproductive health in Uganda, HCPs are not sufficiently equipped to provide adequate contraceptive counselling to young people. Instead, HCPs are left in between the negative influence of social norms and their pragmatic approach to address the needs of young people, especially those seeking PAC. We argue that a clear policy supported by a clear strategy

  5. Healthcare providers balancing norms and practice: challenges and opportunities in providing contraceptive counselling to young people in Uganda - a qualitative study.

    Science.gov (United States)

    Paul, Mandira; Näsström, Sara B; Klingberg-Allvin, Marie; Kiggundu, Charles; Larsson, Elin C

    2016-01-01

    Pregnancies among young women force girls to compromise education, resulting in low educational attainment with subsequent poverty and vulnerability. A pronounced focus is needed on contraceptive use, pregnancy, and unsafe abortion among young women. This study aims to explore healthcare providers' (HCPs) perceptions and practices regarding contraceptive counselling to young people. We conducted 27 in-depth interviews with doctors and midwives working in seven health facilities in central Uganda. Interviews were open-ended and allowed the participant to speak freely on certain topics. We used a topic guide to cover areas topics of interest focusing on post-abortion care (PAC) but also covering contraceptive counselling. Transcripts were transcribed verbatim and data were analysed using thematic analysis. The main theme, HCPs' ambivalence to providing contraceptive counselling to sexually active young people is based on two sub-themes describing the challenges of contraceptive counselling: A) HCPs echo the societal norms regarding sexual practice among young people, while at the same time our findings B) highlights the opportunities resulting from providers pragmatic approach to contraceptive counselling to young women. Providers expressed a self-identified lack of skill, limited resources, and inadequate support from the health system to successfully provide appropriate services to young people. They felt frustrated with the consultations, especially when meeting young women seeking PAC. Despite existing policies for young people's sexual and reproductive health in Uganda, HCPs are not sufficiently equipped to provide adequate contraceptive counselling to young people. Instead, HCPs are left in between the negative influence of social norms and their pragmatic approach to address the needs of young people, especially those seeking PAC. We argue that a clear policy supported by a clear strategy with practical guidelines should be implemented alongside in

  6. Challenges and Opportunities

    International Nuclear Information System (INIS)

    Foster, J.B.

    1999-01-01

    A series of overhead viewgraphs accompanied this presentation. The viewgraphs presented 1998 year-end predictions of oil and gas prices. Comparisons of projected versus actual values for 1998 for natural gas consumption, production, imports and wellhead prices for the United States were also presented. A comparison of projected versus actual consumption values for 1998 in the residential, commercial, industrial and electric generation sectors was included. In many cases actual versus projected values were quite different. The importance of storage to balancing the market was illustrated. Graphs depicting gas production, workover rigs, reserve life comparisons, and GOM natural gas rig count and production for the U.S. were described. Drilling activity in the Gulf of Mexico was summarized. The total wells drilled in 1997 was 1223 compared to 1019 in 1998. The factors affecting deliverability additions on the Gulf of Mexico shelf include smaller new discoveries, diminishing completion opportunities in older fields, few productive zones in new discoveries and a rapid decline rate resulting from smaller reservoirs. 6 tabs., 13 figs

  7. Challenges and opportunities for REDD+

    DEFF Research Database (Denmark)

    Pasgaard, Maya; Sun, Zhanli; Müller, Daniel

    2016-01-01

    Reducing Emissions from Deforestation and forest Degradation (REDD+) is a promising mechanism of payments for ecosystem services with the aim to effectively reduce emissions in an efficient and equitable manner. REDD+ is part of the Paris-agreement reached at the UNFCCC COP21 in December 2015...... the opportunities and challenges of REDD+ for achieving effective, efficient and equitable outcomes and co-benefits (3E+). We substantiate our survey results with a literature review. Results suggest that the challenges in achieving the 3E+ relate to the disproportionality between deforestation drivers...

  8. Rural Entrepreneurship: Challenges and Opportunities

    OpenAIRE

    Imedashvili, Sopiko; Kekua, Ani; Ivchenko, Polina

    2013-01-01

    According to World Bank Report published in 2012, the rural population in Sweden is 15.3 %. Rural population is calculated as difference between total populations minus urban population. 15.3 % clearly shows how important rural areas are for Sweden’s future development. Entrepreneurship plays the integral role in rural area development. However, earlier research has shown only economic perspective of rural development. On the other hand, the new ways to discover the challenges and opportuniti...

  9. Interprofessional Education: Opportunities and Challenges for Psychology.

    Science.gov (United States)

    Ward, Wendy; Zagoloff, Alexandra; Rieck, Cortney; Robiner, William

    2018-02-16

    This manuscript is an outgrowth of an invited panel presentation at the national Association for Psychologists in Academic Health Centers Conference in 2017 on Interprofessional Education (IPE). IPE is a structured and transformative educational strategy designed to provide active learning experiences where trainees from diverse healthcare professions gain shared content knowledge plus collaboration skills as they learn about, from, and with each other. Collaboration skills include understanding professional role distinctions and overlap, effective team-based communication, shared values/ethics and respect for each other's expertise, and teamwork dynamics. It is increasingly important to expand training beyond the intraprofessional activities in which psychology trainees engage to prepare them to participate in interprofessional collaborative care. As healthcare systems move to team-based collaborative practice and value-based reimbursement models, the profession of psychology needs leaders at every academic health center to facilitate the design and/or implementation of IPE activities. The panel of psychologists presented roles that psychologists play in IPE institutional program design and implementation, graduate training programs, and the perspectives of an early career psychologist and psychology trainee. Opportunities and challenges are highlighted, culminating in a call to action. Psychologists must embrace their identity as health professionals and engage their learners in IPE so that the emerging cognitive schemata of healthcare that is developed includes the profession of psychology. Otherwise, healthcare teams and health professionals will not understand the value, roles, or potential contributions of psychologists in enhancing patient care outcomes, ultimately jeopardizing psychologists' referrals, involvement in healthcare delivery, and career opportunities.

  10. ITER safety challenges and opportunities

    International Nuclear Information System (INIS)

    Piet, S.J.

    1991-01-01

    Results of the Conceptual Design Activity (CDA) for the International Thermonuclear Experimental Reactor (ITER) suggest challenges and opportunities. ''ITER is capable of meeting anticipated regulatory dose limits,'' but proof is difficult because of large radioactive inventories needing stringent radioactivity confinement. We need much research and development (R ampersand D) and design analysis to establish that ITER meets regulatory requirements. We have a further opportunity to do more to prove more of fusion's potential safety and environmental advantages and maximize the amount of ITER technology on the path toward fusion power plants. To fulfill these tasks, we need to overcome three programmatic challenges and three technical challenges. The first programmatic challenge is to fund a comprehensive safety and environmental ITER R ampersand D plan. Second is to strengthen safety and environment work and personnel in the international team. Third is to establish an external consultant group to advise the ITER Joint Team on designing ITER to meet safety requirements for siting by any of the Parties. The first of the three key technical challenges is plasma engineering -- burn control, plasma shutdown, disruptions, tritium burn fraction, and steady state operation. The second is the divertor, including tritium inventory, activation hazards, chemical reactions, and coolant disturbances. The third technical challenge is optimization of design requirements considering safety risk, technical risk, and cost. Some design requirements are now too strict; some are too lax. Fuel cycle design requirements are presently too strict, mandating inappropriate T separation from H and D. Heat sink requirements are presently too lax; they should be strengthened to ensure that maximum loss of coolant accident temperatures drop

  11. ITER safety challenges and opportunities

    International Nuclear Information System (INIS)

    Piet, S.J.

    1992-01-01

    This paper reports on results of the Conceptual Design Activity (CDA) for the International Thermonuclear Experimental Reactor (ITER) suggest challenges and opportunities. ITER is capable of meeting anticipated regulatory dose limits, but proof is difficult because of large radioactive inventories needing stringent radioactivity confinement. Much research and development (R ampersand D) and design analysis is needed to establish that ITER meets regulatory requirements. There is a further oportunity to do more to prove more of fusion's potential safety and environmental advantages and maximize the amount of ITER technology on the path toward fusion power plants. To fulfill these tasks, three programmatic challenges and three technical challenges must be overcome. The first step is to fund a comprehensive safety and environmental ITER R ampersand D plan. Second is to strengthen safety and environment work and personnel in the international team. Third is to establish an external consultant group to advise the ITER Joint Team on designing ITER to meet safety requirements for siting by any of the Parties. The first of three key technical challenges is plasma engineering - burn control, plasma shutdown, disruptions, tritium burn fraction, and steady state operation. The second is the divertor, including tritium inventory, activation hazards, chemical reactions, and coolant disturbances. The third technical challenge is optimization of design requirements considering safety risk, technical risk, and cost

  12. IAEA safeguards: Challenges and opportunities

    International Nuclear Information System (INIS)

    1993-01-01

    The history of the IAEA safeguards regime is described. New challenges and opportunities are discussed in connection with the discovery in Iraq of a clandestine nuclear weapons development programme, the difficulties experienced in the implementation of the safeguards agreement with the Democratic People's Republic of Korea, the conclusion of a comprehensive safeguards agreement with Argentina, Brazil and the Brazilian-Argentine Agency for Accounting and Control of Nuclear Materials, recent developments in South Africa, the emergence of newly independent States that made up the former USSR. 2 figs

  13. Multiphysics simulations: challenges and opportunities.

    Energy Technology Data Exchange (ETDEWEB)

    Keyes, D.; McInnes, L. C.; Woodward, C.; Gropp, W.; Myra, E.; Pernice, M. (Mathematics and Computer Science); (KAUST and Columbia Univ.); (Lawrence Livermore National Laboratory); (Univ. of Illinois at Urbana-Champaign); (Univ. of Mich.); (Idaho National Lab.)

    2012-11-29

    This report is an outcome of the workshop Multiphysics Simulations: Challenges and Opportunities, sponsored by the Institute of Computing in Science (ICiS). Additional information about the workshop, including relevant reading and presentations on multiphysics issues in applications, algorithms, and software, is available via https://sites.google.com/site/icismultiphysics2011/. We consider multiphysics applications from algorithmic and architectural perspectives, where 'algorithmic' includes both mathematical analysis and computational complexity and 'architectural' includes both software and hardware environments. Many diverse multiphysics applications can be reduced, en route to their computational simulation, to a common algebraic coupling paradigm. Mathematical analysis of multiphysics coupling in this form is not always practical for realistic applications, but model problems representative of applications discussed herein can provide insight. A variety of software frameworks for multiphysics applications have been constructed and refined within disciplinary communities and executed on leading-edge computer systems. We examine several of these, expose some commonalities among them, and attempt to extrapolate best practices to future systems. From our study, we summarize challenges and forecast opportunities. We also initiate a modest suite of test problems encompassing features present in many applications.

  14. Multiphysics simulations: Challenges and opportunities

    KAUST Repository

    Keyes, David E.; McInnes, Lois Curfman; Woodward, Carol S.; Gropp, William D.; Myra, Eric S.; Pernice, Michael; Bell, John B.; Brown, Jed; Clo, Alain M.; Connors, Jeffrey Mark; Constantinescu, Emil M.; Estep, Donald J.; Evans, Katherine J.; Farhat, Charbel H.; Hakim, Ammar H.; Hammond, Glenn E.; Hansen, Glen A.; Hill, Judith C.; Isaac, Tobin; Jiao, Xiangmin; Jordan, Kirk E.; Kaushik, Dinesh K.; Kaxiras, Efthimios; Koniges, Alice E.; Lee, Kihwan; Lott, Aaron; Lu, Qiming; Magerlein, John H.; Maxwell, Reed M.; McCourt, Michael J.; Mehl, Miriam; Pawlowski, Roger P.; Randles, Amanda Peters; Reynolds, Daniel R.; Riviè re, Bé atrice M.; Rü de, Ulrich; Scheibe, Timothy D.; Shadid, John N.; Sheehan, Brendan; Shephard, Mark S.; Siegel, Andrew R.; Smith, Barry F.; Tang, Xianzhu; Wilson, Cian R G; Wohlmuth, Barbara Ian

    2013-01-01

    We consider multiphysics applications from algorithmic and architectural perspectives, where "algorithmic" includes both mathematical analysis and computational complexity, and "architectural" includes both software and hardware environments. Many diverse multiphysics applications can be reduced, en route to their computational simulation, to a common algebraic coupling paradigm. Mathematical analysis of multiphysics coupling in this form is not always practical for realistic applications, but model problems representative of applications discussed herein can provide insight. A variety of software frameworks for multiphysics applications have been constructed and refined within disciplinary communities and executed on leading-edge computer systems. We examine several of these, expose some commonalities among them, and attempt to extrapolate best practices to future systems. From our study, we summarize challenges and forecast opportunities. © The Author(s) 2012.

  15. Challenges and opportunities in presbycusis.

    Science.gov (United States)

    Parham, Kourosh; McKinnon, Brian J; Eibling, David; Gates, George A

    2011-04-01

    The population aged 65 years and older is increasing at a faster rate than the total population, with predictions that by 2030, 20% of the population will be 65 years or older. In 2006, between 35% and 50% of those aged 65 years or older reportedly had presbycusis, a sensory impairment that contributes to social isolation and loss of autonomy and is associated with anxiety, depression, and cognitive decline. To address these concerns, the Geriatric Committee of the American Academy of Otolaryngology, in conjunction with the Hearing Committee, focused on 3 challenges and opportunities in the management of presbycusis: (1) the financial burden of caring for patients with presbycusis in the face of increasing costs and declining reimbursements; (2) future treatment options arising from improved understanding of the molecular mechanisms underlying presbycusis, and (3) recognition of central presbycusis as a condition commonly superimposed on peripheral age-related hearing loss whose diagnosis and management can improve outcomes.

  16. Multiphysics simulations: Challenges and opportunities

    KAUST Repository

    Keyes, David E.

    2013-02-01

    We consider multiphysics applications from algorithmic and architectural perspectives, where "algorithmic" includes both mathematical analysis and computational complexity, and "architectural" includes both software and hardware environments. Many diverse multiphysics applications can be reduced, en route to their computational simulation, to a common algebraic coupling paradigm. Mathematical analysis of multiphysics coupling in this form is not always practical for realistic applications, but model problems representative of applications discussed herein can provide insight. A variety of software frameworks for multiphysics applications have been constructed and refined within disciplinary communities and executed on leading-edge computer systems. We examine several of these, expose some commonalities among them, and attempt to extrapolate best practices to future systems. From our study, we summarize challenges and forecast opportunities. © The Author(s) 2012.

  17. Green ergonomics: challenges and opportunities.

    Science.gov (United States)

    Hanson, Margaret A

    2013-01-01

    Addressing the causes and consequences of environmental degradation presents significant challenges for humankind. This paper considers what ergonomics/human factors (E/HF) professionals can contribute to understanding and tackling some of the issues that arise through the movement towards a more environmentally sustainable economy. These issues are considered in relation to work in green industries (specifically, sustainable energy production, recycling and organic food production), and there is a need to ensure that these jobs are safe and healthy; the design of products and systems that are 'environmentally friendly' to facilitate their acceptability and use and how E/HF professionals can contribute to understanding and promoting behavioural change relating to environmental choices. The activities of some international organisations in this area are identified and the potential for E/HF involvement is considered. The implications for the E/HF profession are discussed. This paper considers how ergonomics/human factors professionals can contribute to the movement towards more sustainable and 'environmentally friendly' design and work. Potential challenges and opportunities are discussed in relation to jobs in green industries, products and systems and behaviour change.

  18. Measuring healthcare quality: the challenges

    NARCIS (Netherlands)

    van den Heuvel, J.; Niemeijer, G.C.; Does, R.J.M.M.

    2013-01-01

    Purpose - Current health care quality performance indicators appear to be inadequate to inform the public to make the right choices. The aim of this paper is to define a framework and an organizational setting in which valid and reliable healthcare information can be produced to inform the general

  19. Tuberculosis diagnostics: Challenges and opportunities

    Directory of Open Access Journals (Sweden)

    Vijay Nema

    2012-01-01

    Full Text Available Tuberculosis (TB has been a disease affecting almost all parts of the world since ages. Lot many efforts came in the past for improving diagnosis and treatment. Also, an effective vaccine has been sought after for long. With the emergence of resistant strains of Mycobacterium tuberculosis, the causal organisms of tuberculosis, and complexities emerging due to other associated infections and disease conditions, there is a desperate need for further research input in the field. Be it the better medication and care or better resistance management, proper diagnostics holds the key to success. It has been observed that a high burden of the disease was accompanied by resource limitations and poor research set-up. The scenario remained like this for several decades. With the refreshed vision of resourceful countries and funding agencies, funding is being provided in many areas of research in tuberculosis diagnosis and treatment. This review has been written with an aim to bring forth the limitations of available methods in the field of diagnostics and making researchers aware about the changing scenario with better funding opportunities and support. The author visualizes an enthusiasm from all over the world for the development of better modalities and urges scientists to join the struggle at this very perfect time to take the challenge and come forward with innovations in this field.

  20. Challenges and Opportunities for Libraries in Pakistan

    OpenAIRE

    Shafiq UR, Rehman; Pervaiz, Ahmad

    2007-01-01

    Abstract: This paper, based on review of literature, observation, and informal conversations, discusses various challenges regarding finance, collection development, ICTs, human resources, library education, library association and research & development faced by library profession in Pakistan. The opportunities to meet these challenges have also been explored. Keywords: Library challenges and opportunities (Pakistan); Librarianship (Pakistan); Library issues; Library profession in Pa...

  1. Challenges, opportunities and trends in engineering education

    International Nuclear Information System (INIS)

    Rosen, M.A.

    2005-01-01

    Many challenges and opportunities face the engineering profession and engineering education. The engineering profession advances best if challenges are properly addressed, opportunities beneficially exploited and reasoned speculation made on future trends. In this article, the author presents his views on some of the challenges and opportunities facing the engineering education, and possible future trends, with the objective of fostering continued discussion of and action on these issues. This topic is of great importance because the development of engineering education is strongly influenced by the challenges and opportunities it faces and how it responds, and by anticipated future trends. (author)

  2. Neurogenomics: Challenges and opportunities for Ghana

    Directory of Open Access Journals (Sweden)

    Thomas K. Karikari

    2015-06-01

    Full Text Available The application of genomic tools and technologies has shown the potential to help improve healthcare and our understanding of disease mechanisms. While genomic tools are increasingly being applied to research on infectious diseases, malaria and neglected tropical diseases in Africa, an area that has seen little application of genomic approaches on this continent is neuroscience. In this article, we examined the prospects of developing neurogenomics research and its clinical use in Ghana, one of the African countries actively involved in genomics research. We noted that established international research funding sources and foundations in genomic research such as H3ABioNet nodes established at a couple of research centres in Ghana provide excellent platforms for extending the usage of genomic tools and techniques to neuroscience-related research areas. However, existing challenges such as the (i lack of degree programmes in neuroscience, genomics and bioinformatics; (ii low availability of infrastructure and appropriately-trained scientists; and (iii lack of local research funding opportunities, need to be addressed. To promote and safeguard the long-term sustainability of neurogenomics research in the country, the impact of the existing challenges and possible ways of addressing them have been discussed.

  3. THE QATAR HEALTH SYSTEM: CHALLENGES AND OPPORTUNITIES

    Directory of Open Access Journals (Sweden)

    Shaher ALSHAMARI

    2017-06-01

    Full Text Available Qatar’s healthcare system is comparatively new and has experienced noteworthy developments over its brief history. In this paper, our aim is to look at the unique challenges this small nation has faced in building that system. This paper will describe the accomplishments of Qatar’s medical authorities and the challenges they faced. It will also compare public and private healthcare providers. Today, the government of Qatar has financed all the health care for this rapidly-developing, multicultural nation, but it is now planning to introduce medical insurance. This report of its experience will benefit other nations wanting to develop their own healthcare systems.

  4. Can pervasive sensing address current challenges in global healthcare?

    Directory of Open Access Journals (Sweden)

    Louis Atallah

    2012-03-01

    Full Text Available Important challenges facing global healthcare include the increase in the number of people affected by escalating healthcare costs, chronic and infectious diseases, the need for better and more affordable elderly care and expanding urbanisation combined with air and water pollution. Recent advances in pervasive sensing technologies have led to miniaturised sensor networks that can be worn or integrated within the living environment without affecting a person’s daily patterns. These sensors promise to change healthcare from snapshot measurements of physiological parameters to continuous monitoring enabling clinicians to provide guidance on a daily basis. This article surveys several of the solutions provided by these sensor platforms from elderly care to neonatal monitoring and environmental mapping. Some of the opportunities available and the challenges facing the adoption of such technologies in large-scale epidemiological studies are also discussed.

  5. Challenges of Data-driven Healthcare Management

    DEFF Research Database (Denmark)

    Bossen, Claus; Danholt, Peter; Ubbesen, Morten Bonde

    This paper describes the new kind of data-work involved in developing data-driven healthcare based on two cases from Denmark: The first case concerns a governance infrastructure based on Diagnose-Related Groups (DRG), which was introduced in Denmark in the 1990s. The DRG-system links healthcare...... activity and financing and relies of extensive data entry, reporting and calculations. This has required the development of new skills, work and work roles. The second case concerns a New Governance project aimed at developing new performance indicators for healthcare delivery as an alternative to DRG....... Here, a core challenge is select indicators and actually being able to acquire data upon them. The two cases point out that data-driven healthcare requires more and new kinds of work for which new skills, functions and work roles have to be developed....

  6. Future landscapes: opportunities and challenges

    Science.gov (United States)

    John Stanturf

    2015-01-01

    The global magnitude of degraded and deforested areas is best approached by restoring landscapes. Heightened international perception of the importance of forests and trees outside forests (e.g., woodlands, on farms) demands new approaches to future landscapes. The current need for forest restoration is two billion ha; most opportunities are mosaic restoration in the...

  7. Presidential Transition. Challenges and Opportunities

    National Research Council Canada - National Science Library

    Walker, David

    2000-01-01

    .... Attention to these themes will help the new administration successfully implement its agenda and address both long-standing and newly emerging management, fiscal, and other challenges that confront...

  8. Towards Quality Art Education: Challenges and Opportunities ...

    African Journals Online (AJOL)

    Towards Quality Art Education: Challenges and Opportunities. ... Quality art education promotes emotional development, as well as cognitive achievement, which is a key factor to achieve quality education. ... AJOL African Journals Online.

  9. Engineering: issues, challenges and opportunities for development

    CSIR Research Space (South Africa)

    Wall, K

    2010-10-01

    Full Text Available to contribute to greater international understanding of the issues, challenges and opportunities facing engineering, with a particular focus on contributions of our discipline to sustainable development. The Report, one of the most cost-effective reports UNESCO...

  10. Marketing African Leafy Vegetables: Challenges and Opportunities ...

    African Journals Online (AJOL)

    Marketing African Leafy Vegetables: Challenges and Opportunities in the Kenyan Context. ... The market share of ALVs vis-à-vis other vegetable species, particularly kales, cabbages and ... EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT

  11. Plastics recycling: challenges and opportunities.

    Science.gov (United States)

    Hopewell, Jefferson; Dvorak, Robert; Kosior, Edward

    2009-07-27

    Plastics are inexpensive, lightweight and durable materials, which can readily be moulded into a variety of products that find use in a wide range of applications. As a consequence, the production of plastics has increased markedly over the last 60 years. However, current levels of their usage and disposal generate several environmental problems. Around 4 per cent of world oil and gas production, a non-renewable resource, is used as feedstock for plastics and a further 3-4% is expended to provide energy for their manufacture. A major portion of plastic produced each year is used to make disposable items of packaging or other short-lived products that are discarded within a year of manufacture. These two observations alone indicate that our current use of plastics is not sustainable. In addition, because of the durability of the polymers involved, substantial quantities of discarded end-of-life plastics are accumulating as debris in landfills and in natural habitats worldwide. Recycling is one of the most important actions currently available to reduce these impacts and represents one of the most dynamic areas in the plastics industry today. Recycling provides opportunities to reduce oil usage, carbon dioxide emissions and the quantities of waste requiring disposal. Here, we briefly set recycling into context against other waste-reduction strategies, namely reduction in material use through downgauging or product reuse, the use of alternative biodegradable materials and energy recovery as fuel. While plastics have been recycled since the 1970s, the quantities that are recycled vary geographically, according to plastic type and application. Recycling of packaging materials has seen rapid expansion over the last decades in a number of countries. Advances in technologies and systems for the collection, sorting and reprocessing of recyclable plastics are creating new opportunities for recycling, and with the combined actions of the public, industry and governments it

  12. Plastics recycling: challenges and opportunities

    Science.gov (United States)

    Hopewell, Jefferson; Dvorak, Robert; Kosior, Edward

    2009-01-01

    Plastics are inexpensive, lightweight and durable materials, which can readily be moulded into a variety of products that find use in a wide range of applications. As a consequence, the production of plastics has increased markedly over the last 60 years. However, current levels of their usage and disposal generate several environmental problems. Around 4 per cent of world oil and gas production, a non-renewable resource, is used as feedstock for plastics and a further 3–4% is expended to provide energy for their manufacture. A major portion of plastic produced each year is used to make disposable items of packaging or other short-lived products that are discarded within a year of manufacture. These two observations alone indicate that our current use of plastics is not sustainable. In addition, because of the durability of the polymers involved, substantial quantities of discarded end-of-life plastics are accumulating as debris in landfills and in natural habitats worldwide. Recycling is one of the most important actions currently available to reduce these impacts and represents one of the most dynamic areas in the plastics industry today. Recycling provides opportunities to reduce oil usage, carbon dioxide emissions and the quantities of waste requiring disposal. Here, we briefly set recycling into context against other waste-reduction strategies, namely reduction in material use through downgauging or product reuse, the use of alternative biodegradable materials and energy recovery as fuel. While plastics have been recycled since the 1970s, the quantities that are recycled vary geographically, according to plastic type and application. Recycling of packaging materials has seen rapid expansion over the last decades in a number of countries. Advances in technologies and systems for the collection, sorting and reprocessing of recyclable plastics are creating new opportunities for recycling, and with the combined actions of the public, industry and governments it

  13. Environmental assessment: challenges and opportunities

    International Nuclear Information System (INIS)

    Hilbig, J.; Moffett, D.; Beri, K.

    2007-01-01

    As part of a $4.5 billion investment,Bruce Power is refurbishing Bruce A Units 1 and 2, having successfully completed an environmental assessment to return these units to service after a lay-up of almost 10 years. The project includes implementing a series of refurbishments and upgrades which will enhance safety, increase electricity generation capacity and improve reliability for the 30-year extended life of the units. This paper describes four challenges that were successfully managed during the extensive environmental assessment: (i) defining the scope of the Project; (ii) understanding the EA trigger under the Canadian Environmental Assessment Act; (iii) maintaining an effective relationship with the regulatory agencies; and (iv) managing stakeholder communications. (author)

  14. Environmental assessment: challenges and opportunities

    International Nuclear Information System (INIS)

    Hilbig, J.; Moffett, D.; Beri, K.

    2007-01-01

    As part of a $4.5 billion investment, Bruce Power is refurbishing Bruce A Units 1 and 2, having successfully completed an environmental assessment to return these units to service after a lay-up of almost 10 years. The project includes implementing a series of refurbishments and upgrades which will enhance safety, increase electricity generation capacity and improve reliability for the 30-year extended life of the units. This paper describes four challenges that were successfully managed during the extensive environmental assessment: (i) defining the scope of the Project; (ii) understanding the EA trigger under the Canadian Environmental Assessment Act; (iii) maintaining an effective relationship with the regulatory agencies; and (iv) managing stakeholder communications. (author)

  15. Quantum Information: Opportunities and Challenges

    Energy Technology Data Exchange (ETDEWEB)

    Bennink, Ryan S [ORNL

    2008-01-01

    Modern society is shaped by the ability to transmit, manipulate, and store large amounts of information. Although we tend to think of information as abstract, information is physical, and computing is a physical process. How then should we understand information in a quantum world, in which physical systems may exist in multiple states at once and are altered by the very act of observation? This question has evolved into an exciting new field of research called Quantum Information (QI). QI challenges many accepted rules and practices in computer science. For example, a quantum computer would turn certain hard problems into soft problems, and would render common computationally-secure encryption methods (such as RSA) insecure. At the same time, quantum communication would provide an unprecedented kind of intrinsic information security at the level of the smallest physical objects used to store or transmit the information. This talk provides a general introduction to the subject of quantum information and its relevance to cyber security. In the first part, two of the stranger aspects of quantum physics namely, superposition and uncertainty are explained, along with their relation to the concept of information. These ideas are illustrated with a few examples: quantum ID cards, quantum key distribution, and Grover s quantum search algorithm. The state-of-the-art in quantum computing and communication hardware is then discussed, along with the daunting technological challenges that must be overcome. Relevant experimental and theoretical efforts at ORNL are highlighted. The talk concludes with speculations on the short- and long-term impact of quantum information on cyber security.

  16. Challenges in Transgender Healthcare: The Pathology Perspective.

    Science.gov (United States)

    Gupta, Sarika; Imborek, Katherine L; Krasowski, Matthew D

    2016-08-01

    The transgender community is one of the most marginalized sections of our society. The literature is scarce regarding the pathology and laboratory medicine challenges associated with caring for transgender patients. To summarize the available gender-transitioning options and to discuss healthcare challenges, from a pathology/laboratory medicine perspective, in the care of transgender patients. We reviewed the current terminology and epidemiology relevant to the transgender population in preparing our analysis. The main transgender healthcare challenges in pathology/laboratory medicine practice include the inflexibility of electronic medical records in documenting affirmed gender, unfamiliarity among medical and laboratory professional with the needs of and terminology related to the transgender population, lack of reference ranges for laboratory tests, unclear guidelines regarding gender classification for blood donation eligibility criteria, and paucity of experience in handling and interpreting surgical and cytologic specimens from gender-transitioning individuals. Directed efforts to overcome these shortcomings, coupled with a more welcoming posture, are essential to achieving the highest standards of care for the transgender population. © American Society for Clinical Pathology, 2016. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  17. e-Health Cloud: Opportunities and Challenges

    Directory of Open Access Journals (Sweden)

    Jameela Al-Jaroodi

    2012-07-01

    Full Text Available As the costs of healthcare services rise and healthcare professionals are becoming scarce and hard to find, it is imminent that healthcare organizations consider adopting health information technology (HIT systems. HIT allows health organizations to streamline many of their processes and provide services in a more efficient and cost-effective manner. The latest technological trends such as Cloud Computing (CC provide a strong infrastructure and offer a true enabler for HIT services over the Internet. This can be achieved on a pay-as-you-use model of the “e-Health Cloud” to help the healthcare industry cope with current and future demands yet keeping their costs to a minimum. Despite its great potential, HIT as a CC model has not been addressed extensively in the literature. There are no apparent frameworks which clearly encompass all viable schemes and interrelationships between HIT and CC. Therefore, analyzing and comparing the effectiveness of such schemes is important. In this paper we introduce the concept of “e-Health Cloud” highlighting many of its constituents and proposing building an e-health environment and elucidating many of the challenges confronting the success of the e-Health Cloud. We will also discuss different possible solutions to address challenges such as security and privacy.

  18. Healthcare Policy in Romania. Frameworks and Challenges

    Directory of Open Access Journals (Sweden)

    Buţiu Călina Ana

    2016-07-01

    Full Text Available The objective of the paper is to review some of the healthcare policy issues of Romania and identify those challenges which may be addressed through social intervention. Based on statistical data, documents, reports and applicable laws one will review the health condition of Romanian population and the state of the national health system, and will examine the broad strategies and policies currently under the scrutiny of appropriate ministries. The findings of the study suggest looking at health policies also through the lens of social inclusion.

  19. Community Languages in Europe : Challenges and Opportunities

    NARCIS (Netherlands)

    McPake, J.; Martyniuk, W.; Aarts, R.; Broeder, Peter; Latomaa, Sirkku; Mijares, Laura; Tinsley, Teresa

    2004-01-01

    This paper reviews issues affecting school students’ learning of community languages across Europe, with the aim of identifying both challenges and opportunities inherent in the current context. Language education pol icy has become more inclusive of late, addressing the full range of languages

  20. Challenges, opportunities and achievements of nurses' research ...

    African Journals Online (AJOL)

    This paper explores the challenges, opportunities and achievements that nursing students face when supervised across culture, language borders and distance. A qualitative, exploratory, single descriptive case study was used in the city of Lubumbashi in the Democratic Republic of Congo. A total of 18 participants took part ...

  1. Challenges and Opportunities in Teaching Mathematics

    Science.gov (United States)

    Goos, Merrilyn

    2016-01-01

    At the special conference celebrating the 50th anniversary of the Australian Association of Mathematics Teachers (AAMT), the author was asked to speak about the challenges and opportunities in teaching mathematics as a stimulus for discussion of AAMT's "future directions". With an open invitation to be a little provocative, the author…

  2. Diverse Classrooms--Opportunities and Challenges

    Science.gov (United States)

    van Driel, Barry; van Dijk, Lutz

    2010-01-01

    In April 2009, the Anne Frank House in Amsterdam invited more than 30 experts in the field of Holocaust education from a dozen countries for a three-day seminar to share their thoughts and experiences to provide insight into the kinds of opportunities and challenges educators might face in the future when teaching about the Holocaust in diverse…

  3. Responsibilities, opportunities and challenges in geophysical exploration

    International Nuclear Information System (INIS)

    Rytle, R.J.

    1982-01-01

    Geophysical exploration for engineering purposes is conducted to decrease the risk in encountering site uncertainties in construction of underground facilities. Current responsibilities, opportunities and challenges for those with geophysical expertise are defined. These include: replacing the squiggly line format, developing verification sites for method evaluations, applying knowledge engineering and assuming responsibility for crucial national problems involving rock mechanics expertise

  4. Computer Aided Modelling – Opportunities and Challenges

    DEFF Research Database (Denmark)

    Cameron, Ian; Gani, Rafiqul

    2011-01-01

    -based solutions to significant problems? The important issues of workflow and data flow are discussed together with fit-for-purpose model development. As well, the lack of tools around multiscale modelling provides opportunities for the development of efficient tools to address such challenges. The ability...

  5. Nanotechnology in biorobotics: opportunities and challenges

    International Nuclear Information System (INIS)

    Ricotti, Leonardo; Menciassi, Arianna

    2015-01-01

    Nanotechnology recently opened a series of unexpected technological opportunities that drove the emergence of novel scientific and technological fields, which have the potential to dramatically change the lives of millions of citizens. Some of these opportunities have been already caught by researchers working in the different fields related to biorobotics, while other exciting possibilities still lie on the horizon. This article highlights how nanotechnology applications recently impacted the development of advanced solutions for actuation and sensing and the achievement of microrobots, nanorobots, and non-conventional larger robotic systems. The open challenges are described, together with the most promising research avenues involving nanotechnology

  6. Strategic alliances in healthcare: opportunities for the Veterans Affairs healthcare system.

    Science.gov (United States)

    Halverson, P K; Kaluzny, A D; Young, G J

    1997-01-01

    Strategic alliances are proving to be effective strategies for responding and adapting to changing environments, and as such they offer the U.S. Department of Veterans Affairs (VA) healthcare system valuable opportunities for accomplishing the goals of its major reorganization effort. This article begins with an examination of basic strategic-alliance structures that are employed across many different types of industries. Next, consideration is given to the ways in which these basic alliance structures may be adapted to the unique organizations and individuals that serve as providers, purchasers, and consumers of health services. Finally, this article explores how models of strategic alliance in healthcare can be tailored to the specific needs and constraints of the VA healthcare system through an examination of existing and potential alliance opportunities.

  7. The quantified patient of the future: Opportunities and challenges.

    Science.gov (United States)

    Majmudar, Maulik D; Colucci, Lina Avancini; Landman, Adam B

    2015-09-01

    The healthcare system is undergoing rapid transformation as national policies increase patient access, reward positive health outcomes, and push for an end to the current era of episodic care. Advances in health sensors are rapidly moving diagnostic and monitoring capabilities into consumer products, enabling new care models. Although hospitals and health care providers have been slow to embrace novel health technologies, such innovations may help meet mounting pressure to provide timely, high quality, and low-cost care to large populations. This leading edge perspective focuses on the quantified-self movement and highlights the opportunities and challenges for patients, providers, and researchers. Copyright © 2015 Elsevier Inc. All rights reserved.

  8. The future of hydrogen - opportunities and challenges

    International Nuclear Information System (INIS)

    Ball, Michael; Wietschel, Martin

    2009-01-01

    The following article is reproduced from 'The Hydrogen Economy: Opportunities and Challenges', edited by Michael Ball and Martin Wietschel, to be published by Cambridge University Press in June 2009. In the light of ever-increasing global energy use, the increasing cost of energy services, concerns over energy supply security, climate change and local air pollution, this book centres around the question of how growing energy demand for transport can be met in the long term. Given the sustained interest in and controversial discussion of the prospects of hydrogen, the authors highlight the opportunities and the challenges of introducing hydrogen as alternative fuel in the transport sector from an economic, technical and environmental point of view. Through its multi-disciplinary approach the book provides a broad range of researchers, decision makers and policy makers with a solid and wide-ranging knowledge base concerning the hydrogen economy. (author)

  9. Introduction of Basel III: Opportunities and Challenges

    OpenAIRE

    Madzova, Violeta

    2011-01-01

    Basel III is an opportunity as well as a challenge for the banks. It was developed from the existing Basel II framework, and the most signifi cant differences for banks are the introduction of liquidity and leverage ratios, and enhanced minimum capital requirements. An effective implementation of Basel III need to demonstrate to regulators, customers, and shareholders that the bank are recovering well from the global banking crisis of 2008 and provide a solid foundation for the next dev...

  10. Equipment Replacement Decision Making: Opportunities and Challenges

    OpenAIRE

    Fan, Wei (David); Gemar, Mason D.; Machemehl, Randy

    2012-01-01

    The primary function of equipment managers is to replace the right equipment at the right time and at the lowest overall cost. In this paper, the opportunities and challenges associated with equipment replacement optimization (ERO) are discussed in detail. First, a comprehensive review of the state-of-the art and state-of-the practice literature for the ERO problem is conducted. Second, a dynamic programming (DP) based optimization solution methodology is presented to solve the ERO problem. T...

  11. The medical leadership challenge in healthcare is an identity challenge.

    Science.gov (United States)

    Andersson, Thomas

    2015-01-01

    The purpose of this article is to describe and analyse the identity challenges that physicians with medical leadership positions face. Four qualitative case studies were performed to address the fact that identity is processual, relational and situational. Physicians with managerial roles were interviewed, as well as their peers, supervisors and subordinates. Furthermore, observations were made to understand how different identities are displayed in action. This study illustrates that medical leadership implies identity struggles when physicians have manager positions, because of the different characteristics of the social identities of managers and physicians. Major differences are related between physicians as autonomous individuals in a system and managers as subordinates to the organizational system. There are psychological mechanisms that evoke the physician identity more often than the managerial identity among physicians who are managers, which explains why physicians who are managers tend to remain foremost physicians. The implications of the findings, that there are major identity challenges by being both a physician and manager, suggest that managerial physicians might not be the best prerequisite for medical leadership, but instead, cooperative relationships between physicians and non-physician managers might be a less difficult way to support medical leadership. Acknowledging and addressing identity challenges can be important both in creating structures in organizations and designing the training for managers in healthcare (both physicians and non-physicians) to support medical leadership. Medical leadership is most often related to organizational structure and/or leadership skills, but this paper discusses identity requirements and challenges related to medical leadership.

  12. Challenges and Opportunities of Airborne Metagenomics

    KAUST Repository

    Behzad, H.

    2015-05-06

    Recent metagenomic studies of environments, such as marine and soil, have significantly enhanced our understanding of the diverse microbial communities living in these habitats and their essential roles in sustaining vast ecosystems. The increase in the number of publications related to soil and marine metagenomics is in sharp contrast to those of air, yet airborne microbes are thought to have significant impacts on many aspects of our lives from their potential roles in atmospheric events such as cloud formation, precipitation, and atmospheric chemistry to their major impact on human health. In this review, we will discuss the current progress in airborne metagenomics, with a special focus on exploring the challenges and opportunities of undertaking such studies. The main challenges of conducting metagenomic studies of airborne microbes are as follows: 1) Low density of microorganisms in the air, 2) efficient retrieval of microorganisms from the air, 3) variability in airborne microbial community composition, 4) the lack of standardized protocols and methodologies, and 5) DNA sequencing and bioinformatics-related challenges. Overcoming these challenges could provide the groundwork for comprehensive analysis of airborne microbes and their potential impact on the atmosphere, global climate, and our health. Metagenomic studies offer a unique opportunity to examine viral and bacterial diversity in the air and monitor their spread locally or across the globe, including threats from pathogenic microorganisms. Airborne metagenomic studies could also lead to discoveries of novel genes and metabolic pathways relevant to meteorological and industrial applications, environmental bioremediation, and biogeochemical cycles.

  13. Characterisation: Challenges and Opportunities - A UK Perspective

    International Nuclear Information System (INIS)

    Emptage, Matthew; Loudon, David; Mcleod, Richard; Milburn, Helen

    2016-01-01

    Characterisation plays a very important role in the nuclear industry supporting: the development and implementation of decommissioning strategies/plans (and the optimisation of associated costs through reduction in technical risks); regulatory compliance demonstration; waste prevention/minimisation; evaluation and optimisation of worker radiation doses; and maintaining public confidence. Recognising these important drivers, the UK regulators are working with the UK Nuclear Decommissioning Authority (NDA) to undertake a review of characterisation practice in the UK nuclear (decommissioning) industry. The objective of the characterisation review is to understand the current characterisation challenges and to determine strategic and tactical opportunities (including sharing of standards and guidance, capabilities, learning from experience, good practice, research and development, training, quality assurance) to optimise characterisation practice. The work is being undertaken through review of nuclear operator's characterisation practice, with input from the NDA, the UK regulators, nuclear operators and representatives from the supply chain, and through consideration of good practice case studies. To support this, a catalogue of relevant national/international guidance documents is also be compiled. Finally a workshop with representatives from all parties has taken place to consider the findings and establish a common understanding of challenges and opportunities and to start to consider how they can be addressed. The review is establishing a collective (UK regulator's, NDA; nuclear operator's and supply chain) understanding of opportunities to improve characterisation practice in the UK. The characterisation review process is described and early results are presented and discussed. Subsequent work in 2016 will be required to prioritise the opportunities and to build a consensus to facilitate development and implementation of an improvement plan. The aim

  14. Big data business models: Challenges and opportunities

    Directory of Open Access Journals (Sweden)

    Ralph Schroeder

    2016-12-01

    Full Text Available This paper, based on 28 interviews from a range of business leaders and practitioners, examines the current state of big data use in business, as well as the main opportunities and challenges presented by big data. It begins with an account of the current landscape and what is meant by big data. Next, it draws distinctions between the ways organisations use data and provides a taxonomy of big data business models. We observe a variety of different business models, depending not only on sector, but also on whether the main advantages derive from analytics capabilities or from having ready access to valuable data sources. Some major challenges emerge from this account, including data quality and protectiveness about sharing data. The conclusion discusses these challenges, and points to the tensions and differing perceptions about how data should be governed as between business practitioners, the promoters of open data, and the wider public.

  15. New challenges and opportunities for industrial biotechnology.

    Science.gov (United States)

    Chen, Guo-Qiang

    2012-08-20

    Industrial biotechnology has not developed as fast as expected due to some challenges including the emergences of alternative energy sources, especially shale gas, natural gas hydrate (or gas hydrate) and sand oil et al. The weaknesses of microbial or enzymatic processes compared with the chemical processing also make industrial biotech products less competitive with the chemical ones. However, many opportunities are still there if industrial biotech processes can be as similar as the chemical ones. Taking advantages of the molecular biology and synthetic biology methods as well as changing process patterns, we can develop bioprocesses as competitive as chemical ones, these including the minimized cells, open and continuous fermentation processes et al.

  16. Plant molecular farming: Opportunities and challenges

    Directory of Open Access Journals (Sweden)

    Valkova Rumyana

    2013-01-01

    Full Text Available The modern human life is impossible without products derived from the classical, contemporary biotechnology. However, large scale production of biotechnology wares opens a discussion about the economic impact, waste management, biosafety, and bioethical issues. Plant molecular farming offers a relatively inexpensive option for yielding of many valuable products and demonstrates number of advantages over the classical technologies, but also brings the question of further development perspectives, hazard identification and risk assessment. This review is focused on those two questions: opportunities offered and challenges faced by modern plant molecular farming systems.

  17. Challenges and opportunities for dietary campaigns

    DEFF Research Database (Denmark)

    Bech-Larsen, Tino; Aschemann-Witzel, Jessica; Verbeke, Wim

    2013-01-01

    The objective of our research was to explore and discuss the challenges and opportunities inherent to the management of public healthy eating campaigns. The discussion is based on a study of campaign managers’ perceptions of nine successfully implemented European healthy eating campaigns. Based...... on these interviews, we suggest that social marketing compared to commercial food marketing is not necessarily at a disadvantage; rather, social marketers working to promote healthy eating can benefit from the formation of alliances with public and private partners, the empowerment of their targets and of those who...... influence the targets, the development of credible and emotive messages and relationships with media and public institutions....

  18. Wind energy global trends: Opportunities and challenges

    International Nuclear Information System (INIS)

    Ancona, D.F.

    1995-01-01

    Wind energy is one of the least cost and environmentally attractive new electricity source options for many parts of the world. Because of new wind turbine technology, reduced costs, short installation time, and environmental benefits, countries all over the world are beginning to once again develop one of the world's oldest energy technologies. A unique set of opportunities and challenges now faces the wind industry and its proponents. This paper discusses the potential and challenges of wind power. The US Department of Energy (DOE) is working closely with industry to develop new, improved wind turbine technology and to support both domestic and international deployment. The US DOE Wind Program is discussed within this context

  19. Preventing radiological terrorism - opportunities and challenges

    International Nuclear Information System (INIS)

    Barlow, Maegon E.

    2016-01-01

    The Office of Radiological Security (ORS), within the U.S. Department of Energy's National Nuclear Security Administration, enhances global security by preventing high activity radioactive materials from use in acts of terrorism. This is a challenging task considering that high activity radiological materials are ubiquitous, constantly moving and mostly found in operational civil facilities. The implementation of the ORS mission is based on a three pillar strategy - protect, remove and reduce. ORS works both domestically and internationally with government authorities, law enforcement, and businesses to protect radioactive sources used for vital medical, research, and commercial purposes, remove and dispose of disused radioactive sources, and reduce the global reliance on radioactive sources through the promotion of viable non-isotopic alternative technologies. ORS has active engagement in all 50 States and in over 80 countries. This presentation will provide an overview of ORS protect, remove, and reduce strategy, as well as security challenges and opportunities

  20. Cancer nanomedicine: progress, challenges and opportunities.

    Science.gov (United States)

    Shi, Jinjun; Kantoff, Philip W; Wooster, Richard; Farokhzad, Omid C

    2017-01-01

    The intrinsic limits of conventional cancer therapies prompted the development and application of various nanotechnologies for more effective and safer cancer treatment, herein referred to as cancer nanomedicine. Considerable technological success has been achieved in this field, but the main obstacles to nanomedicine becoming a new paradigm in cancer therapy stem from the complexities and heterogeneity of tumour biology, an incomplete understanding of nano-bio interactions and the challenges regarding chemistry, manufacturing and controls required for clinical translation and commercialization. This Review highlights the progress, challenges and opportunities in cancer nanomedicine and discusses novel engineering approaches that capitalize on our growing understanding of tumour biology and nano-bio interactions to develop more effective nanotherapeutics for cancer patients.

  1. Data Sharing: Convert Challenges into Opportunities

    Directory of Open Access Journals (Sweden)

    Ana Sofia Figueiredo

    2017-12-01

    Full Text Available Initiatives for sharing research data are opportunities to increase the pace of knowledge discovery and scientific progress. The reuse of research data has the potential to avoid the duplication of data sets and to bring new views from multiple analysis of the same data set. For example, the study of genomic variations associated with cancer profits from the universal collection of such data and helps in selecting the most appropriate therapy for a specific patient. However, data sharing poses challenges to the scientific community. These challenges are of ethical, cultural, legal, financial, or technical nature. This article reviews the impact that data sharing has in science and society and presents guidelines to improve the efficient sharing of research data.

  2. Data Sharing: Convert Challenges into Opportunities.

    Science.gov (United States)

    Figueiredo, Ana Sofia

    2017-01-01

    Initiatives for sharing research data are opportunities to increase the pace of knowledge discovery and scientific progress. The reuse of research data has the potential to avoid the duplication of data sets and to bring new views from multiple analysis of the same data set. For example, the study of genomic variations associated with cancer profits from the universal collection of such data and helps in selecting the most appropriate therapy for a specific patient. However, data sharing poses challenges to the scientific community. These challenges are of ethical, cultural, legal, financial, or technical nature. This article reviews the impact that data sharing has in science and society and presents guidelines to improve the efficient sharing of research data.

  3. Challenges and opportunities of airborne metagenomics.

    Science.gov (United States)

    Behzad, Hayedeh; Gojobori, Takashi; Mineta, Katsuhiko

    2015-05-06

    Recent metagenomic studies of environments, such as marine and soil, have significantly enhanced our understanding of the diverse microbial communities living in these habitats and their essential roles in sustaining vast ecosystems. The increase in the number of publications related to soil and marine metagenomics is in sharp contrast to those of air, yet airborne microbes are thought to have significant impacts on many aspects of our lives from their potential roles in atmospheric events such as cloud formation, precipitation, and atmospheric chemistry to their major impact on human health. In this review, we will discuss the current progress in airborne metagenomics, with a special focus on exploring the challenges and opportunities of undertaking such studies. The main challenges of conducting metagenomic studies of airborne microbes are as follows: 1) Low density of microorganisms in the air, 2) efficient retrieval of microorganisms from the air, 3) variability in airborne microbial community composition, 4) the lack of standardized protocols and methodologies, and 5) DNA sequencing and bioinformatics-related challenges. Overcoming these challenges could provide the groundwork for comprehensive analysis of airborne microbes and their potential impact on the atmosphere, global climate, and our health. Metagenomic studies offer a unique opportunity to examine viral and bacterial diversity in the air and monitor their spread locally or across the globe, including threats from pathogenic microorganisms. Airborne metagenomic studies could also lead to discoveries of novel genes and metabolic pathways relevant to meteorological and industrial applications, environmental bioremediation, and biogeochemical cycles. © The Author(s) 2015. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

  4. Additive manufacturing in production: challenges and opportunities

    Science.gov (United States)

    Ahuja, Bhrigu; Karg, Michael; Schmidt, Michael

    2015-03-01

    Additive manufacturing, characterized by its inherent layer by layer fabrication methodology has been coined by many as the latest revolution in the manufacturing industry. Due to its diversification of Materials, processes, system technology and applications, Additive Manufacturing has been synonymized with terminology such as Rapid prototyping, 3D printing, free-form fabrication, Additive Layer Manufacturing, etc. A huge media and public interest in the technology has led to an innovative attempt of exploring the technology for applications beyond the scope of the traditional engineering industry. Nevertheless, it is believed that a critical factor for the long-term success of Additive Manufacturing would be its ability to fulfill the requirements defined by the traditional manufacturing industry. A parallel development in market trends and product requirements has also lead to a wider scope of opportunities for Additive Manufacturing. The presented paper discusses some of the key challenges which are critical to ensure that Additive Manufacturing is truly accepted as a mainstream production technology in the industry. These challenges would highlight on various aspects of production such as product requirements, process management, data management, intellectual property, work flow management, quality assurance, resource planning, etc. In Addition, changing market trends such as product life cycle, mass customization, sustainability, environmental impact and localized production will form the foundation for the follow up discussion on the current limitations and the corresponding research opportunities. A discussion on ongoing research to address these challenges would include topics like process monitoring, design complexity, process standardization, multi-material and hybrid fabrication, new material development, etc.

  5. Emergency contraception in Senegal: challenges and opportunities.

    Science.gov (United States)

    Mané, Babacar; Brady, Martha; Ramarao, Saumya; Thiam, Ababacar

    2015-02-01

    This paper highlights lessons from introductory efforts and presents new data on community, provider and key opinion leader perspectives to support expanded use of emergency contraception (EC) in Senegal. The paper draws on four data sources: (i) a literature review; (ii) a secondary analysis of a household survey conducted by the Urban Reproductive Health Initiative; (iii) in-depth interviews with key opinion leaders; and (iv) a quantitative survey of healthcare providers from a range of service delivery points. ANALYSIS OF DATA: Knowledge of EC among women is low in urban areas, with only 20% of women having heard of the method and 4% having ever used it. There were serious gaps in providers' technical knowledge about EC; only 57% knew its mode of action and 34% were aware of the need for timely use (within 120 h). Moreover, nearly half reported reluctance to provide EC to married women and even fewer were willing to provide it to youths, particularly to adolescent girls. Responses from key opinion leaders were mixed, demonstrating ambivalence about EC and how it could be offered. In Senegal, the current positive political climate for family planning provides a good opportunity for strengthening EC programming to address knowledge and attitudinal barriers among providers, key opinion leaders and communities.

  6. Precision medicine: opportunities, possibilities, and challenges for patients and providers.

    Science.gov (United States)

    Adams, Samantha A; Petersen, Carolyn

    2016-07-01

    Precision medicine approaches disease treatment and prevention by taking patients' individual variability in genes, environment, and lifestyle into account. Although the ideas underlying precision medicine are not new, opportunities for its more widespread use in practice have been enhanced by the development of large-scale databases, new methods for categorizing and representing patients, and computational tools for analyzing large datasets. New research methods may create uncertainty for both healthcare professionals and patients. In such situations, frameworks that address ethical, legal, and social challenges can be instrumental for facilitating trust between patients and providers, but must protect patients while not stifling progress or overburdening healthcare professionals. In this perspective, we outline several ethical, legal, and social issues related to the Precision Medicine Initiative's proposed changes to current institutions, values, and frameworks. This piece is not an exhaustive overview, but is intended to highlight areas meriting further study and action, so that precision medicine's goal of facilitating systematic learning and research at the point of care does not overshadow healthcare's goal of providing care to patients. © The Author 2016. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  7. Opportunities and challenges for biodiesel fuel

    International Nuclear Information System (INIS)

    Lin, Lin; Cunshan, Zhou; Vittayapadung, Saritporn; Xiangqian, Shen; Mingdong, Dong

    2011-01-01

    Fossil fuel resources are decreasing daily. As a renewable energy, biodiesel has been receiving increasing attention because of the relevance it gains from the rising petroleum price and its environmental advantages. This review highlights some of the perspectives for the biodiesel industry to thrive as an alternative fuel, while discussing opportunities and challenges of biodiesel. This review is divided in three parts. First overview is given on developments of biodiesel in past and present, especially for the different feedstocks and the conversion technologies of biodiesel industry. More specifically, an overview is given on possible environmental and social impacts associated with biodiesel production, such as food security, land change and water source. Further emphasis is given on the need for government's incentives and public awareness for the use and benefits of biodiesel, while promoting policies that will not only endorse the industry, but also promote effective land management. (author)

  8. Nuclear fuel supply: challenges and opportunities

    International Nuclear Information System (INIS)

    Lowen, S.

    2006-01-01

    Prices of uranium, conversion services and enrichment services have all significantly increased in the last few years. These price increases have generally been driven by a tightening in the supply of these products and services, mostly due to long lead times required to bring these products and services to the market. This paper will describe the various steps in the nuclear fuel cycle for natural and enriched uranium fuel, will discuss the development of the front-end fuel cycle for low void reactivity fuel, and will address the challenges faced in the long-term supply of each component, particularly in the light of potential demand increases as a result of a nuclear renaissance. The opportunities for new capacity and uranium production will be outlined and the process required to achieve sufficient new supply will be discussed. (author)

  9. New challenges and opportunities for industrial biotechnology

    Science.gov (United States)

    2012-01-01

    Industrial biotechnology has not developed as fast as expected due to some challenges including the emergences of alternative energy sources, especially shale gas, natural gas hydrate (or gas hydrate) and sand oil et al. The weaknesses of microbial or enzymatic processes compared with the chemical processing also make industrial biotech products less competitive with the chemical ones. However, many opportunities are still there if industrial biotech processes can be as similar as the chemical ones. Taking advantages of the molecular biology and synthetic biology methods as well as changing process patterns, we can develop bioprocesses as competitive as chemical ones, these including the minimized cells, open and continuous fermentation processes et al. PMID:22905695

  10. New challenges and opportunities for industrial biotechnology

    Directory of Open Access Journals (Sweden)

    Chen Guo-Qiang

    2012-08-01

    Full Text Available Abstract Industrial biotechnology has not developed as fast as expected due to some challenges including the emergences of alternative energy sources, especially shale gas, natural gas hydrate (or gas hydrate and sand oil et al. The weaknesses of microbial or enzymatic processes compared with the chemical processing also make industrial biotech products less competitive with the chemical ones. However, many opportunities are still there if industrial biotech processes can be as similar as the chemical ones. Taking advantages of the molecular biology and synthetic biology methods as well as changing process patterns, we can develop bioprocesses as competitive as chemical ones, these including the minimized cells, open and continuous fermentation processes et al.

  11. Risk-based regulation: Challenges and opportunities

    International Nuclear Information System (INIS)

    Bari, R.A.

    1995-01-01

    Over the last twenty years, man has witnessed a gradual but steady movement toward increased usage of risk-based methods and results in the regulatory process. The ''risk perspective'' as a supportive view to existing (non-risk-based or deterministic) information used in decision making has a firm foothold now in most countries that regulate nuclear power. Furthermore, in the areas outside the nuclear power field, such as health risk assessment, risk-based information is used increasingly to make decisions on potential impacts of chemical, biological, and radiological exposures. Some of the principal concepts and issues that are pertinent to risk-based regulation are reviewed. There is a growing interest in most countries in the use of risk-based methods and results to facilitate decision-making associated with regulatory processes. A summary is presented of the challenges and opportunities related to expanded use of risk-based regulation

  12. Cyberlearning for Climate Literacy: Challenges and Opportunities

    Science.gov (United States)

    McCaffrey, M. S.; Buhr, S. M.; Gold, A. U.; Ledley, T. S.; Mooney, M. E.; Niepold, F.

    2010-12-01

    Cyberlearning tools provide cost and carbon-efficient avenues for fostering a climate literate society through online engagement with learners. With climate change education becoming a Presidential Priority in 2009, funding for grants from NSF, NASA and NOAA is leading to a new generation of cyberlearning resources that supplement existing online resources. This paper provides an overview of challenges and opportunities relating to the online delivery of high quality, often complex climate science by examining several existing and emerging efforts, including the Climate Literacy and Energy Awareness Network (CLEAN,) a National Science Digital Library Pathway, the development by CIRES Education and Outreach of the Inspiring Climate Education Excellence (ICEE) online course, TERC’s Earth Exploration Toolbook (EET,) DataTools, and EarthLab modules, the NOAA Climate Stewards Education Program (CSEP) that utilizes the NSTA E-Learning Center, online efforts by members of the Federation of Earth Science Information Partners (ESIP), UCAR’s Climate Discovery program, and the Climate Adaptation, Mitigation e-Learning (CAMeL) project. In addition, we will summarize outcomes of the Cyberlearning for Climate Literacy workshop held in Washington DC in the Fall of 2009 and examine opportunities for teachers to develop and share their own lesson plans based on climate-related web resources that currently lack built-in learning activities, assessments or teaching tips.

  13. Technology in Parkinson disease: Challenges and Opportunities

    Science.gov (United States)

    Espay, Alberto J.; Bonato, Paolo; Nahab, Fatta; Maetzler, Walter; Dean, John M.; Klucken, Jochen; Eskofier, Bjoern M.; Merola, Aristide; Horak, Fay; Lang, Anthony E.; Reilmann, Ralf; Giuffrida, Joe; Nieuwboer, Alice; Horne, Malcolm; Little, Max A.; Litvan, Irene; Simuni, Tanya; Dorsey, E. Ray; Burack, Michelle A.; Kubota, Ken; Kamondi, Anita; Godinho, Catarina; Daneault, Jean-Francois; Mitsi, Georgia; Krinke, Lothar; Hausdorff, Jeffery M.; Bloem, Bastiaan R.; Papapetropoulos, Spyros

    2016-01-01

    The miniaturization, sophistication, proliferation, and accessibility of technologies are enabling the capturing of more and previously inaccessible phenomena in Parkinson disease (PD). However, more information has not translated into greater understanding of disease complexity to satisfy diagnostic and therapeutic needs. Challenges include non-compatible technology platforms, the need for wide-scale and long-term deployment of sensor technology (in particular among vulnerable elderly patients), and the gap between the “big data” acquired with sensitive measurement technologies and their limited clinical application. Major opportunities could be realized if new technologies are developed as part of open-source and/or open-hardware platforms enabling multi-channel data capture, sensitive to the broad range of motor and non-motor problems that characterize PD, and adaptable into self-adjusting, individualized treatment delivery systems. The International Parkinson and Movement Disorders Society Task Force on Technology is entrusted to convene engineers, clinicians, researchers, and patients to promote the development of integrated measurement and closed-loop therapeutic systems with high patient adherence that also serve to: 1) encourage the adoption of clinico-pathophysiologic phenotyping and early detection of critical disease milestones; 2) enhance tailoring of symptomatic therapy; 3) improve subgroup targeting of patients for future testing of disease modifying treatments; and 4) identify objective biomarkers to improve longitudinal tracking of impairments in clinical care and research. This article summarizes the work carried out by the Task Force toward identifying challenges and opportunities in the development of technologies with potential for improving the clinical management and quality of life of individuals with PD. PMID:27125836

  14. Healthcare-associated infections: challenges to public health in Brazil.

    Science.gov (United States)

    Padoveze, Maria Clara; Fortaleza, Carlos Magno Castelo Branco

    2014-12-01

    This study presents a critical evaluation of the scientific literature related to this subject, aiming to assess the policies and administrative issues regarding the prevention and magnitude of healthcare-associated infections and discuss the challenges for their prevention in Brazil. The topics discussed included historical and administrative issues, challenges imposed by the characteristics of the healthcare system and the territorial dimension, laboratorial support limitations, costs, institutional culture, professional qualification, and patient engagement. It is urgent to hold a nationwide discussion among government representatives, institutions, and healthcare workers and users to overcome these challenges.

  15. THE OPPORTUNITIES AND CHALLENGES OF MICROINSURANCE

    Directory of Open Access Journals (Sweden)

    Bente Corneliu

    2011-07-01

    Full Text Available Microinsurance is a term increasingly used to refer to insurance characterized by low premium and low caps or low coverage limits, sold as part of a typical risk-pooling and marketing arrangements, and designed to service low-income people and businesses not served by typical social or commercial insurance schemes. As a relatively new field, few studies evaluating the impact of microinsurance projects exist. Of these, even fewer have a rigorous methodology leading to reliable results. Our research aimed to: - examine the viability of microinsurance as a mechanism of risk transfer and tool for risk management in developing countries; - provide a state of the art analysis of microinsurance for a better understanding of currently operational microinsurance schemes; - reflect on the opportunities and challenges of microinsurance in developing countries, highlighting both the potential benefits and limitations of microinsurance as an instrument for transferring risk; - consider the interests and perspectives of different stakeholders and the incentives and disincentives for participating and investing in a micro-insurance scheme; - enhance dialogue and collaboration on this topic between and within the commercial insurance sector and the disaster risk reduction communities; - assess the opportunity of introducing microinsurance in Romania. Reflecting on the opportunities and challenges of introducing microinsurance in Romania, there is absolutely necessary to understand both the supply side (current insurance market and the demand side (risks faced by low-income persons and the coping strategies used to manage these risks. The majority of the primary research was conducted on-site in Romania, in Oradea and its environs, during the month of December 2010. Qualitative research techniques were utilized, including focus group discussions (FGD and guided individual interviews with members of both the public and private sector, as well as with

  16. ONLINE READING COMPREHENSION: CHALLENGES AND OPPORTUNITIES

    Directory of Open Access Journals (Sweden)

    Julie Coiro/

    2014-12-01

    Full Text Available This paper details a number of challenges and opportunities for today’s learners when reading for information on the Internet. After defining online reading comprehension from a new literacies perspective and how it appears to be different than offline reading comprehension, I highlight details about four of the biggest challenges for today’s learners. These include 1 understanding and becoming proficient with the new literacy skills and practices needed for online research; 2 developing a special kind of digital wisdom that focuses on learning how to learn with the Internet; 3 taking on new roles in a digital culture that expects learners to actively participate and contribute with new knowledge as a member of their community; and 4 developing positive attitudes toward using the Internet for academic work. The second part of the paper shares examples of how skilled online readers can use the steps of online inquiry to think more deeply about topics that interest them; develop a personal voice as they share ideas with others; and work collaboratively to build meaning and new digital products that enable them to make a difference in their world, or matter. You can explore the research and resources from this presentation in more depth at .

  17. Hydrology Domain Cyberinfrastructures: Successes, Challenges, and Opportunities

    Science.gov (United States)

    Horsburgh, J. S.

    2015-12-01

    Anticipated changes to climate, human population, land use, and urban form will alter the hydrology and availability of water within the water systems on which the world's population relies. Understanding the effects of these changes will be paramount in sustainably managing water resources, as well as maintaining associated capacity to provide ecosystem services (e.g., regulating flooding, maintaining instream flow during dry periods, cycling nutrients, and maintaining water quality). It will require better information characterizing both natural and human mediated hydrologic systems and enhanced ability to generate, manage, store, analyze, and share growing volumes of observational data. Over the past several years, a number of hydrology domain cyberinfrastructures have emerged or are currently under development that are focused on providing integrated access to and analysis of data for cross-domain synthesis studies. These include the Consortium of Universities for the Advancement of Hydrologic Science, Inc. (CUAHSI) Hydrologic Information System (HIS), the Critical Zone Observatory Information System (CZOData), HyroShare, the BiG CZ software system, and others. These systems have focused on sharing, integrating, and analyzing hydrologic observations data. This presentation will describe commonalities and differences in the cyberinfrastructure approaches used by these projects and will highlight successes and lessons learned in addressing the challenges of big and complex data. It will also identify new challenges and opportunities for next generation cyberinfrastructure and a next generation of cyber-savvy scientists and engineers as developers and users.

  18. Hybrid governance of aquaculture: Opportunities and challenges.

    Science.gov (United States)

    Vince, Joanna; Haward, Marcus

    2017-10-01

    The development of third party assessment and certification of fisheries and aquaculture has provided new forms of governance in sectors that were traditionally dominated by state based regulation. Emerging market based approaches are driven by shareholder expectations as well as commitment to corporate social responsibility, whereas community engagement is increasingly centered on the questions of social license to operate. Third party assessment and certification links state, market and community into an interesting and challenging hybrid form of governance. While civil society organizations have long been active in pursuing sustainable and safe seafood production, the development of formal non-state based certification provides both opportunities and challenges, and opens up interesting debates over hybrid forms of governance. This paper explores these developments in coastal marine resources management, focusing on aquaculture and the development and operation of the Aquaculture Stewardship Council. It examines the case of salmonid aquaculture in Tasmania, Australia, now Australia's most valuable seafood industry, which remains the focus of considerable community debate over its siting, operation and environmental impact. Copyright © 2017 Elsevier Ltd. All rights reserved.

  19. Modeling for Ecosystem Services: Challenges and Opportunities

    Science.gov (United States)

    Guswa, A. J.; Brauman, K. A.; Ghile, Y.

    2012-12-01

    Ecosystem services are those values provided to human society by the structure and processes of ecosystems and landscapes. Water-related services include the transformation of precipitation impulses into supplies of water for hydropower, irrigation, and industrial and municipal uses, the retention and removal of applied nutrients and pollutants, flood-damage mitigation, recreation, and the provision of cultural and aesthetic values. Incorporation of changes to the value of these services in land-use planning and decision making requires identification of the relevant services, engagement of stakeholders, knowledge of how land-use changes impact water quality, quantity, and timing, and mechanisms for putting value on the hydrologic and biogeochemical changes. We present three examples that highlight the characteristics, challenges, and opportunities associated with prototypical decisions that incorporate ecosystem services values: scenario analysis, payment for ecosystem services, and optimal spatial planning. Through these examples, we emphasize the challenges of data availability, model resolution and complexity, and attribution of value. We also provide some suggestions for ways forward.

  20. Crowdsourcing in biomedicine: challenges and opportunities.

    Science.gov (United States)

    Khare, Ritu; Good, Benjamin M; Leaman, Robert; Su, Andrew I; Lu, Zhiyong

    2016-01-01

    The use of crowdsourcing to solve important but complex problems in biomedical and clinical sciences is growing and encompasses a wide variety of approaches. The crowd is diverse and includes online marketplace workers, health information seekers, science enthusiasts and domain experts. In this article, we review and highlight recent studies that use crowdsourcing to advance biomedicine. We classify these studies into two broad categories: (i) mining big data generated from a crowd (e.g. search logs) and (ii) active crowdsourcing via specific technical platforms, e.g. labor markets, wikis, scientific games and community challenges. Through describing each study in detail, we demonstrate the applicability of different methods in a variety of domains in biomedical research, including genomics, biocuration and clinical research. Furthermore, we discuss and highlight the strengths and limitations of different crowdsourcing platforms. Finally, we identify important emerging trends, opportunities and remaining challenges for future crowdsourcing research in biomedicine. Published by Oxford University Press 2015. This work is written by US Government employees and is in the public domain in the US.

  1. Big Data and Health Economics: Opportunities, Challenges and Risks

    Directory of Open Access Journals (Sweden)

    Diego Bodas-Sagi

    2018-03-01

    Full Text Available Big Data offers opportunities in many fields. Healthcare is not an exception. In this paper we summarize the possibilities of Big Data and Big Data technologies to offer useful information to policy makers. In a world with tight public budgets and ageing populations we feel necessary to save costs in any production process. The use of outcomes from Big Data could be in the future a way to improve decisions at a lower cost than today. In addition to list the advantages of properly using data and technologies from Big Data, we also show some challenges and risks that analysts could face. We also present an hypothetical example of the use of administrative records with health information both for diagnoses and patients.

  2. THE PHENOMENON OF MIGRATION. OPPORTUNITIES AND CHALLENGES

    Directory of Open Access Journals (Sweden)

    Carmen BOGHEAN

    2016-07-01

    Full Text Available Migration is not a new phenomenon, neither for Europe, nor for the entire world and it exists since the beginning of mankind. Over time, this kind of international mobility generated many opportunities, but many challenges as well. Being an extremely important and complex phenomenon, both in economic terms and mostly from the social perspective, mass emigration has never been more intense as nowadays. Together with this particular complexity, the intensity of the migration phenomenon reveals each individual’s profound freedom desire, but also the acute need to ensure a better future for himself and especially for his family. Currently, an ever increasing number of individuals migrate in search of a better place, changing regions, countries or even continents. Witnessing the events that transcend the people all around the world, we consider that migration generates economic, social and cultural, but also political profound changes. These major changes require the involvement of the political actors, namely the governments, in creating a favorable and reliable framework so as the society and decision makers to understand that immigrants represent an opportunity for the emerging economies and not a phenomenon that should be criticized. In this paper we aim to follow the theories regarding the migration process, as well as the changes it generates, taking into consideration that of the 507 million current inhabitants of the EU, approximately 20 million are from countries outside the EU. We consider this research to be underlain, taking into consideration that regardless of the form it takes, in Europe immigration is and will remain a difficult to manage reality.

  3. Multi-GNSS Opportunities and Challenges

    Science.gov (United States)

    Al-Shaery, A.; Zhang, S.; Lim, S.; Rizos, C.

    2012-04-01

    but also the hardware. Recent research has identified one of the challenges users may face if precise positioning is sought (Takac, 2009, Yamada et al., 2010, Wanninger, 2011). A user of heterogeneous receiver pairs will experience ambiguity fixing challenges due to inter-channel bias which cannot be cancelled by differencing GLONASS observations, pseudorange or carrier-phase. This paper outlines the opportunities and challenges of combining two currently fully operational GNSS systems (GPS and GLONASS) for precise positioning solutions. Discussion and analysis considering mathematical modelling challenges and users' selection of hardware constraints will be performed.

  4. Modular manufacturing processes : Status, challenges, and opportunities

    NARCIS (Netherlands)

    Baldea, Michael; Edgar, Thomas F.; Stanley, Bill L.; Kiss, Anton A.

    2017-01-01

    Chemical companies are constantly seeking new, high-margin growth opportunities, the majority of which lie in high-grade, specialty chemicals, rather than in the bulk sector. To realize these opportunities, manufacturers are increasingly considering decentralized, flexible production facilities:

  5. Institutional review boards: Challenges and opportunities

    Directory of Open Access Journals (Sweden)

    Ravindra B Ghooi

    2014-01-01

    Full Text Available Institutional Review Boards (IRBs are an important link in subject protection program, and their function defines ethical credentials of research. Of late there has been a furore in the country over the number of deaths in clinical research, and allegations of unethical research. Clinical trials have been discussed in medical and lay press and even in the parliament, these discussions called for strengthening the subject protection program. The Central Drug Standards and Control Organization (CDSCO, amended the Schedule Y, by issuing three amendments to introduce new compensation rules and registration of IRBs functioning in the country. IRBs in India face a variety of challenges, and need support from the regulators or independent experts. This is also an opportunity to revamp the subject protection program and strengthen the IRB functioning. An independent advisory body comprising of experts who have hands on experience in administering IRBs, is essential to provide support to IRBs in the country. This body should be independent of regulatory influence and work with IRBs to strengthen them.

  6. Clinical EPR: Unique Opportunities and Some Challenges

    Science.gov (United States)

    Swartz, Harold M.; Williams, Benjamin B.; Zaki, Bassem I.; Hartford, Alan C.; Jarvis, Lesley A.; Chen, Eunice; Comi, Richard J.; Ernstoff, Marc S.; Hou, Huagang; Khan, Nadeem; Swarts, Steven G.; Flood, Ann B.; Kuppusamy, Periannan

    2014-01-01

    Electron paramagnetic resonance (EPR) spectroscopy has been well established as a viable technique for measurement of free radicals and oxygen in biological systems, from in vitro cellular systems to in vivo small animal models of disease. However, the use of EPR in human subjects in the clinical setting, although attractive for a variety of important applications such as oxygen measurement, is challenged with several factors including the need for instrumentation customized for human subjects, probe and regulatory constraints. This paper describes the rationale and development of the first clinical EPR systems for two important clinical applications, namely, measurement of tissue oxygen (oximetry), and radiation dose (dosimetry) in humans. The clinical spectrometers operate at 1.2 GHz frequency and use surface loop resonators capable of providing topical measurements up to 1 cm depth in tissues. Tissue pO2 measurements can be carried out noninvasively and repeatedly after placement of an oxygen-sensitive paramagnetic material (currently India ink) at the site of interest. Our EPR dosimetry system is capable of measuring radiation-induced free radicals in the tooth of irradiated human subjects to determine the exposure dose. These developments offer potential opportunities for clinical dosimetry and oximetry, which include guiding therapy for individual patients with tumors or vascular disease, by monitoring of tissue oxygenation. Further work is in progress to translate this unique technology to routine clinical practice. PMID:24439333

  7. Emerging Biometric Modalities: Challenges and Opportunities

    Science.gov (United States)

    Gafurov, Davrondzhon

    Recent advances in sensor technology and wide spread use of various electronics (computers, PDA, mobile phones etc.) provide new opportunities for capturing and analyses of novel physiological and behavioural traits of human beings for biometric authentication. This paper presents an overview of several such types of human characteristics that have been proposed as alternatives to traditional types of biometrics. We refer to these characteristics as emerging biometrics. We survey various types of emerging modalities and techniques, and discuss their pros and cons. Emerging biometrics faces several limitations and challenges which include subject population coverage (focusing mostly on adults); unavailability of benchmark databases; little research with respect to vulnerability/robustness against attacks; and some privacy concerns they may arise. In addition, recognition performance of emerging modalities are generally less accurate compared to the traditional biometrics. Despite all of these emerging biometrics posses their own benefits and advantages compared to traditional biometrics which makes them still attractive for research. First of all, emerging biometrics can always serve as a complementary source for identity information; they can be suitable in applications where traditional biometrics are difficult or impossible to adapt such as continuous or periodic re-verification of the user's identity etc.

  8. Big Data: Survey, Technologies, Opportunities, and Challenges

    Directory of Open Access Journals (Sweden)

    Nawsher Khan

    2014-01-01

    Full Text Available Big Data has gained much attention from the academia and the IT industry. In the digital and computing world, information is generated and collected at a rate that rapidly exceeds the boundary range. Currently, over 2 billion people worldwide are connected to the Internet, and over 5 billion individuals own mobile phones. By 2020, 50 billion devices are expected to be connected to the Internet. At this point, predicted data production will be 44 times greater than that in 2009. As information is transferred and shared at light speed on optic fiber and wireless networks, the volume of data and the speed of market growth increase. However, the fast growth rate of such large data generates numerous challenges, such as the rapid growth of data, transfer speed, diverse data, and security. Nonetheless, Big Data is still in its infancy stage, and the domain has not been reviewed in general. Hence, this study comprehensively surveys and classifies the various attributes of Big Data, including its nature, definitions, rapid growth rate, volume, management, analysis, and security. This study also proposes a data life cycle that uses the technologies and terminologies of Big Data. Future research directions in this field are determined based on opportunities and several open issues in Big Data domination. These research directions facilitate the exploration of the domain and the development of optimal techniques to address Big Data.

  9. South Asia energy security: Challenges and opportunities

    International Nuclear Information System (INIS)

    Kumar Singh, Bhupendra

    2013-01-01

    South Asia has witnessed a growing imbalance between energy demand and its supply from indigenous sources resulting in increased import dependence. Energy endowments differ among the South Asian countries. However, access to the significant energy resources in the neighboring countries is denied, which increases the cost of energy supply and reduces energy security of the individual countries and of the region as a whole. The countries in the region could benefit significantly only by strengthening the mechanism of energy trade through improved connectivity. Therefore, greater cooperation within South Asia could be one of the most effective ways to deal with this Regional Energy deficit and ensure Energy Security of the Region. - Highlights: • No South Asian country is going to be able to meet its energy needs domestically. • Fostering cross border energy trade and promotion of investments opportunities are key solutions. • India’s neighbors have huge potential in hydroelectricity. • Co-operation among nations to tap the energy resource can be a win–win situation for all. • However it faces certain challenges

  10. Big data: survey, technologies, opportunities, and challenges.

    Science.gov (United States)

    Khan, Nawsher; Yaqoob, Ibrar; Hashem, Ibrahim Abaker Targio; Inayat, Zakira; Ali, Waleed Kamaleldin Mahmoud; Alam, Muhammad; Shiraz, Muhammad; Gani, Abdullah

    2014-01-01

    Big Data has gained much attention from the academia and the IT industry. In the digital and computing world, information is generated and collected at a rate that rapidly exceeds the boundary range. Currently, over 2 billion people worldwide are connected to the Internet, and over 5 billion individuals own mobile phones. By 2020, 50 billion devices are expected to be connected to the Internet. At this point, predicted data production will be 44 times greater than that in 2009. As information is transferred and shared at light speed on optic fiber and wireless networks, the volume of data and the speed of market growth increase. However, the fast growth rate of such large data generates numerous challenges, such as the rapid growth of data, transfer speed, diverse data, and security. Nonetheless, Big Data is still in its infancy stage, and the domain has not been reviewed in general. Hence, this study comprehensively surveys and classifies the various attributes of Big Data, including its nature, definitions, rapid growth rate, volume, management, analysis, and security. This study also proposes a data life cycle that uses the technologies and terminologies of Big Data. Future research directions in this field are determined based on opportunities and several open issues in Big Data domination. These research directions facilitate the exploration of the domain and the development of optimal techniques to address Big Data.

  11. Big Data: Survey, Technologies, Opportunities, and Challenges

    Science.gov (United States)

    Khan, Nawsher; Yaqoob, Ibrar; Hashem, Ibrahim Abaker Targio; Inayat, Zakira; Mahmoud Ali, Waleed Kamaleldin; Alam, Muhammad; Shiraz, Muhammad; Gani, Abdullah

    2014-01-01

    Big Data has gained much attention from the academia and the IT industry. In the digital and computing world, information is generated and collected at a rate that rapidly exceeds the boundary range. Currently, over 2 billion people worldwide are connected to the Internet, and over 5 billion individuals own mobile phones. By 2020, 50 billion devices are expected to be connected to the Internet. At this point, predicted data production will be 44 times greater than that in 2009. As information is transferred and shared at light speed on optic fiber and wireless networks, the volume of data and the speed of market growth increase. However, the fast growth rate of such large data generates numerous challenges, such as the rapid growth of data, transfer speed, diverse data, and security. Nonetheless, Big Data is still in its infancy stage, and the domain has not been reviewed in general. Hence, this study comprehensively surveys and classifies the various attributes of Big Data, including its nature, definitions, rapid growth rate, volume, management, analysis, and security. This study also proposes a data life cycle that uses the technologies and terminologies of Big Data. Future research directions in this field are determined based on opportunities and several open issues in Big Data domination. These research directions facilitate the exploration of the domain and the development of optimal techniques to address Big Data. PMID:25136682

  12. Perovskite Solar Cells: Potentials, Challenges, and Opportunities

    Directory of Open Access Journals (Sweden)

    Muhammad Imran Ahmed

    2015-01-01

    Full Text Available Heralded as a major scientific breakthrough of 2013, organic/inorganic lead halide perovskite solar cells have ushered in a new era of renewed efforts at increasing the efficiency and lowering the cost of solar energy. As a potential game changer in the mix of technologies for alternate energy, it has emerged from a modest beginning in 2012 to efficiencies being claimed at 20.1% in a span of just two years. This remarkable progress, encouraging at one end, also points to the possibility that the potential may still be far from being fully realized. With greater insight into the photophysics involved and optimization of materials and methods, this technology stands to match or even exceed the efficiencies for single crystal silicon solar cells. With thin film solution processability, applicability to flexible substrates, and being free of liquid electrolyte, this technology combines the benefits of Dye Sensitized Solar Cells (DSSCs, Organic Photovoltaics (OPVs, and thin film solar cells. In this review we present a brief historic perspective to this development, take a cognizance of the current state of the art, and highlight challenges and the opportunities.

  13. The state of psychogeriatrics in Europe: challenges and opportunities in six European countries

    NARCIS (Netherlands)

    Fernandes, L.; Mateos, R.; Engedal, K.; von Gunten, A.; Stek, M.L.; Ramakrishnan, A.; Ihl, R.; Wang, H.; Mintzer, J.; Brodaty, H.

    2015-01-01

    With the increase in aging all over the world, and the elderly population nearly tripling from 524 million (8% of the world's population) in 2010 to 1.5 billion (16% of the world's population) in 2050, we will face new challenges and opportunities in providing healthcare. In 2050, it is estimated

  14. mHealth For Aging China: Opportunities and Challenges.

    Science.gov (United States)

    Sun, Jing; Guo, Yutao; Wang, Xiaoning; Zeng, Qiang

    2016-01-01

    The aging population with chronic and age-related diseases has become a global issue and exerted heavy burdens on the healthcare system and society. Neurological diseases are the leading chronic diseases in the geriatric population, and stroke is the leading cause of death in China. However, the uneven distribution of caregivers and critical healthcare workforce shortages are major obstacles to improving disease outcome. With the advancement of wearable health devices, cloud computing, mobile technologies and Internet of Things, mobile health (mHealth) is rapidly developing and shows a promising future in the management of chronic diseases. Its advantages include its ability to improve the quality of care, reduce the costs of care, and improve treatment outcomes by transferring in-hospital treatment to patient-centered medical treatment at home. mHealth could also enhance the international cooperation of medical providers in different time zones and the sharing of high-quality medical service resources between developed and developing countries. In this review, we focus on trends in mHealth and its clinical applications for the prevention and treatment of diseases, especially aging-related neurological diseases, and on the opportunities and challenges of mHealth in China. Operating models of mHealth in disease management are proposed; these models may benefit those who work within the mHealth system in developing countries and developed countries.

  15. Aspiring Pain Practitioners in India: Assessing Challenges and Building Opportunities

    Science.gov (United States)

    Bhatnagar, Sushma; Patel, Anuradha; Raja, Srinivasa N

    2018-01-01

    Background: Pain medicine is a developing specialty, aimed at relieving pain and suffering, enhancing function, and improving the quality of life of patients. Pain is often ignored, under-reported and mismanaged by health-care providers. Aspiring pain physicians in India face many challenges and barriers in advancing their specialty. Objectives: The objective of this study is to determine the challenges in establishing a pain practice in India and to discuss the opportunities and strategies to overcome these barriers. Subjects and Methods: Face-to-face interactive sessions were held with 60 aspiring pain physicians of India who were chosen as registrants to an International Association for the Study of Pain-Indian Society for Study of Pain multidisciplinary evidence-based pain management program conducted at Delhi and Mumbai. The available opportunities, practical issues and the hurdles in becoming a pain specialist were analyzed and summarized in this commentary. Results: The major barriers identified were: (1) Inadequate knowledge and absence of structured, educational and training courses, (2) bureaucratic hurdles, and (3) concerns of opioid misuse and addiction. The opportunities for personal growth and that of the specialty that could be utilized include the creation of a pain resource team, increasing community awareness, changing attitudes of other physicians toward pain specialty, and research and evidence building of the effectiveness of pain management strategies. Conclusion: India needs a structured teaching and training program in the area of pain medicine that is affiliated by the Medical Council of India or other reputed boards of medical education and certification. There is an urgent need to include pain management in the undergraduate and postgraduate medical curriculum. Enhancing community level awareness by public health education campaigns, developing networks of pain physicians, and appropriate marketing of the specialty is needed to make pain

  16. Aspiring Pain Practitioners in India: Assessing Challenges and Building Opportunities.

    Science.gov (United States)

    Bhatnagar, Sushma; Patel, Anuradha; Raja, Srinivasa N

    2018-01-01

    Pain medicine is a developing specialty, aimed at relieving pain and suffering, enhancing function, and improving the quality of life of patients. Pain is often ignored, under-reported and mismanaged by health-care providers. Aspiring pain physicians in India face many challenges and barriers in advancing their specialty. The objective of this study is to determine the challenges in establishing a pain practice in India and to discuss the opportunities and strategies to overcome these barriers. Face-to-face interactive sessions were held with 60 aspiring pain physicians of India who were chosen as registrants to an International Association for the Study of Pain-Indian Society for Study of Pain multidisciplinary evidence-based pain management program conducted at Delhi and Mumbai. The available opportunities, practical issues and the hurdles in becoming a pain specialist were analyzed and summarized in this commentary. The major barriers identified were: (1) Inadequate knowledge and absence of structured, educational and training courses, (2) bureaucratic hurdles, and (3) concerns of opioid misuse and addiction. The opportunities for personal growth and that of the specialty that could be utilized include the creation of a pain resource team, increasing community awareness, changing attitudes of other physicians toward pain specialty, and research and evidence building of the effectiveness of pain management strategies. India needs a structured teaching and training program in the area of pain medicine that is affiliated by the Medical Council of India or other reputed boards of medical education and certification. There is an urgent need to include pain management in the undergraduate and postgraduate medical curriculum. Enhancing community level awareness by public health education campaigns, developing networks of pain physicians, and appropriate marketing of the specialty is needed to make pain medicine recognized and utilized as a valuable specialty.

  17. Aspiring pain practitioners in India: Assessing challenges and building opportunities

    Directory of Open Access Journals (Sweden)

    Sushma Bhatnagar

    2018-01-01

    Full Text Available Background: Pain medicine is a developing specialty, aimed at relieving pain and suffering, enhancing function, and improving the quality of life of patients. Pain is often ignored, under-reported and mismanaged by health-care providers. Aspiring pain physicians in India face many challenges and barriers in advancing their specialty. Objectives: The objective of this study is to determine the challenges in establishing a pain practice in India and to discuss the opportunities and strategies to overcome these barriers. Subjects and Methods: Face-to-face interactive sessions were held with 60 aspiring pain physicians of India who were chosen as registrants to an International Association for the Study of Pain-Indian Society for Study of Pain multidisciplinary evidence-based pain management program conducted at Delhi and Mumbai. The available opportunities, practical issues and the hurdles in becoming a pain specialist were analyzed and summarized in this commentary. Results: The major barriers identified were: (1 Inadequate knowledge and absence of structured, educational and training courses, (2 bureaucratic hurdles, and (3 concerns of opioid misuse and addiction. The opportunities for personal growth and that of the specialty that could be utilized include the creation of a pain resource team, increasing community awareness, changing attitudes of other physicians toward pain specialty, and research and evidence building of the effectiveness of pain management strategies. Conclusion: India needs a structured teaching and training program in the area of pain medicine that is affiliated by the Medical Council of India or other reputed boards of medical education and certification. There is an urgent need to include pain management in the undergraduate and postgraduate medical curriculum. Enhancing community level awareness by public health education campaigns, developing networks of pain physicians, and appropriate marketing of the specialty is

  18. Indian heavy water programme - challenges and opportunities

    International Nuclear Information System (INIS)

    Aruldoss Kanthiah, W.S.

    2010-01-01

    state of export of Heavy Water to other countries like South Korea, China and USA, putting India on the map of nuclear material (Heavy Water) exporting countries. This paper elaborates in detail the challenges and opportunities faced during the past four decades and how successfully we improved the performance of heavy water plants in terms of production, productivity, safety and cost reduction. (author)

  19. COMPLEX NETWORKS IN CLIMATE SCIENCE: PROGRESS, OPPORTUNITIES AND CHALLENGES

    Data.gov (United States)

    National Aeronautics and Space Administration — COMPLEX NETWORKS IN CLIMATE SCIENCE: PROGRESS, OPPORTUNITIES AND CHALLENGES KARSTEN STEINHAEUSER, NITESH V. CHAWLA, AND AUROOP R. GANGULY Abstract. Networks have...

  20. Understanding Challenges and Opportunities of Preventive Blood Pressure Self-Monitoring at Home

    DEFF Research Database (Denmark)

    Grönvall, Erik; Verdezoto, Nervo

    2013-01-01

    methods to understand existing challenges and uncover opportunities of self-monitoring technologies to support preventive healthcare activities among older adults. Emerging challenges from our study were: rule complexity for self-measuring, reliability of measurements, interpretation, understanding...... to support people’s preventive self-monitoring needs compared with existing solutions. Furthermore, supporting the active and informed citizen can improve older adult’s care abilities, awareness and activation towards preventive care....

  1. An Overview of the Challenges and Opportunities for Globalization ...

    African Journals Online (AJOL)

    The paper is an overview of the existing challenges and opportunities of globalization of Nigerian libraries. It examine the challenges and opportunities for the establishment of viable information and communication. Technologies (ICTs) and recommends the way forward for interconnectivity of Nigerian libraries to facilitate ...

  2. Hazardous drugs: new challenges, new opportunities

    Directory of Open Access Journals (Sweden)

    Silvia Valero García

    2016-03-01

    Full Text Available Occupational exposure to hazardous drugs can cause harmful effects on health professionals and several protective measures must be taken. Nevertheless, classification of hazardous drugs is not the same in all the published repertoires and the terminology is still confusing: hazardous drugs, biohazardous drugs or risky drugs are terms improperly described and can define very different drugs with a very different hazard profiles. In Spain, there is not an updated official list of hazardous drugs, and healthcare professionals must consider and follow other published lists. In our opinion, it is mandatory to do a consensus among these professionals, administration and labor union organizations in order to clarify some conflictive questions not only in healthcare settings but in investigational and academic scenarios too. These multidisciplinary groups should be involved also in teaching new and non-experienced personnel and in the knowledge reinforcement for the experienced ones

  3. India: nuclear policy, opportunities and challenges

    International Nuclear Information System (INIS)

    Vaddevolu Balaji Nagendra Kumar

    2009-01-01

    India is not the proliferator of nuclear weapons technology. India FBRs will expand the life of a given consignment of uranium in the nuclear power reactors from 60 to about 211 years and the thorium based reactors to over 2000 years respectively. The Indo-US Nuclear deal has paved the way for uranium supplies to Indian reactors from the NSG (Nuclear Suppliers Group) (comprising 45 countries). It is an opportunity for India to produce energy economically. The major challenge for India is to abstain from using the civilian nuclear reactors for military purpose and to strategically limit the fissile material in content and usage. There are parties interested in supplying Uranium to India and parties interested in imposing checks on the military use of nuclear reactors. In the former category we could place Governments and companies interested in supplying Uranium, companies interested in building and operating nuclear power reactors in India and academia. In the later category, we could place IAEA (International Atomic Energy Agency), US politicians and Pentagon. (Author)

  4. Challenges and opportunities related to postgraduate evidence ...

    African Journals Online (AJOL)

    The wireless internet connection mainly used in this model was not reliable. However, there were opportunities experienced by the learners. These included easy interaction between the learners and the facilitator at any time. The model also reduced instructor dependence and made the learners more responsible of their ...

  5. United Nations Peacekeeping Operations: Challenges and Opportunities

    Science.gov (United States)

    2012-04-27

    close the gap between aspiration and performance…makes the difference between civilisation and chaos” AND OPPORTUNITIES - Dag Hammarskjöld...ONUB) and left behind a democratic local and national structure. 10 UN also successfully completed the referendum in Sudan in 2011(UNMIS) which

  6. Market realities: new challenges and opportunities

    International Nuclear Information System (INIS)

    1996-01-01

    The market outlook for the natural gas industry was the focus of discussion at this conference. Presentations included papers on energy and supply forecasting, natural gas supply and demand and market opportunities, growth, economics, and issues in natural gas transportation. Pricing dynamics of these energy resources and the complexities of the energy market were also addressed. tabs., figs

  7. Looking Forward: New Challenges and Opportunities

    Science.gov (United States)

    Bushnell, Elizabeth J.

    2012-01-01

    It is essential for higher education professionals to remain abreast of industry trends, emerging fields, and changing requirements that affect the job market and advanced education opportunities for new graduates. Equally important is a continual review of evolving strategies for success in the job search itself. Common practices in today's…

  8. Challenges and opportunities in multichannel customer management

    NARCIS (Netherlands)

    Neslin, Scott A.; Grewal, Dhruv; Leghorn, Robert; Shankar, Venkatesh; Teerling, Marije L.; Thomas, Jacquelyn S.; Verhoef, Peter C.

    2006-01-01

    Multichannel customer management is the design, deployment, coordination, and evaluation of channels through which firms and customers interact, with the goal of enhancing customer value through effective customer acquisition, retention, and development. The authors identify five major challenges

  9. Challenges and opportunities in multichannel customer management

    NARCIS (Netherlands)

    Neslin, Scott A.; Grewal, Dhruv; Leghorn, Robert; Shankar, Venkatesh; Teerling, Marije L.; Thomas, Jacquelyn S.; Verhoef, Peter C.

    Multichannel customer management is the design, deployment, coordination, and evaluation of channels through which firms and customers interact, with the goal of enhancing customer value through effective customer acquisition, retention, and development. The authors identify five major challenges

  10. Globalization And Education: Challenges And Opportunities

    OpenAIRE

    Sadegh Bakhtiari; H. Shajar

    2011-01-01

    The impact of globalization on culture and educational system is a major concern. Some people saw it as a treat for traditional institutions such as the family and the school, another argument saw benefits in overturning traditional and developing modern attitudes. this paper will analysis the positive and negative impacts of globalization on education for developing countries. Effective education systems are the foundation of opportunities to lead a decent life. Ensuring that all children ha...

  11. Neurofeedback: Challenges, Applications, and Opportunities for Education

    OpenAIRE

    Chan, Shuet Ying Sofina

    2015-01-01

    This thesis reviews the current state-of-the-art in neurofeedback research and then goes on to consider three fundamental problems for the psychology of education: first, to what extent can the mind cause changes in the brain at will; second, to what extent can studies in neurofeedback be considered to have validity; and third, given positive outcomes for the first two, to what extent can students become more adept at neurofeedback. Opportunities of neurofeedback for education are contingent ...

  12. Promoting nurse practitioner practice through research: opportunities, challenges, and lessons.

    Science.gov (United States)

    Hayes, Eileen

    2006-04-01

    To discuss the opportunities derived, challenges faced, and lessons learned in the research process, including recruiting and retaining nurse practitioner (NP) participants, obtaining institutional approval, and solving research team issues in a National Institutes of Health/National Institute of Nursing Research (NIH/NINR)-funded study of communication between NPs and their older patients in managed care and non-managed care settings. The video-taped interactions between 30 NPs and 150 patients, research team experiences in conducting the research, and a review of relevant literature. Key factors in NP study participation included recognizing the importance of research in demonstrating the effectiveness of the NP role and for advancing the profession, having participated in previous research, enjoying the research process, employer incentives, membership in NP professional organizations, relationships with the university and the school of nursing conducting the research, and knowledge of the coinvestigator's work. NP recruitment was facilitated by word of mouth, professional organization assistance, and articles in a widely distributed, free nursing journal. Data collection was significantly delayed by attrition of NP participants, logistical problems with scheduling and travel, and varied approval procedures by Institutional Review Boards (IRBs) at study sites. The pace of nursing research could be much more efficient if IRB processes involved fewer bureaucratic entanglements. Preliminary study findings, however, show positive outcomes for older patients after NP care. To demonstrate positive patient outcomes and move the NP profession forward, NPs must be willing to commit to participation in research on their effectiveness as providers in today's healthcare environment.

  13. Big Data and Analytics in Higher Education: Opportunities and Challenges

    Science.gov (United States)

    Daniel, Ben

    2015-01-01

    Institutions of higher education are operating in an increasingly complex and competitive environment. This paper identifies contemporary challenges facing institutions of higher education worldwide and explores the potential of Big Data in addressing these challenges. The paper then outlines a number of opportunities and challenges associated…

  14. Strategic Investment Funds : Opportunities and Challenges

    OpenAIRE

    Halland, Havard; Noel, Michel; Tordo, Silvana; Kloper-Owens, Jacob J.

    2016-01-01

    Over the past 15 years, the number of government-sponsored strategic investment funds has grown rapidly in countries at all income levels. This paper identifies some of the challenges that these funds face in their endeavor to achieve economic policy objectives while also securing commercial financial returns—the so-called double bottom line. Through the review of the objectives, investmen...

  15. Independent midwifery practice: Opportunities and challenges | du ...

    African Journals Online (AJOL)

    A qualitative approach was used and midwives, who work in solo (independent) practice, were identified on the internet and via Facebook and invited to participate. Interviews and narrative reports were used for data gathering. Although passionate about their jobs, the most challenging aspect for the midwives, was inter- ...

  16. Biomedical engineering at UCT - challenges and opportunities.

    Science.gov (United States)

    Douglas, Tania S

    2012-03-02

    The biomedical engineering programme at the University of Cape Town has the potential to address some of South Africa's unique public health challenges and to contribute to growth of the local medical device industry, directly and indirectly, through research activities and postgraduate education. Full realisation of this potential requires engagement with the clinical practice environment and with industry.

  17. Opportunities and Challenges with Digital Open Badges

    Science.gov (United States)

    Farmer, Tadd; West, Richard E.

    2016-01-01

    With increasing interest in competency and outcome-based education, and the blending of formal and informal learning, there is increasing need for credentials to match these learning paradigms. In this article, the authors discuss the benefits, challenges, and potential future directions for open digital badges--one potential alternative…

  18. 76 FR 5626 - Notice and Opportunity for Hearing: SinoFresh Healthcare, Inc.

    Science.gov (United States)

    2011-02-01

    ... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-63776; File No. 0-49764] Notice and Opportunity for Hearing: SinoFresh Healthcare, Inc. January 26, 2011 Notice is hereby given that on November 1, 2010, SinoFresh Healthcare, Inc. (Applicant) filed with the Securities and Exchange Commission a Form...

  19. Opportunities and Challenges in Crowdsourced Wardriving

    DEFF Research Database (Denmark)

    Sapiezynski, Piotr; Gatej, Radu; Mislove, Alan

    2015-01-01

    Knowing the physical location of a mobile device is crucial for a number of context-aware applications. This information is usually obtained using the Global Positioning System (GPS), or by calculating the position based on proximity of WiFi access points with known location (where the position...... are collected by mobile devices automatically, and are maintained by large mobile OS providers. As a result, the research community has a poor understanding of the challenges in creating and using large-scale WiFi localization databases. We address this situation using the deployment of over 800 mobile devices...... to real users over a 1.5 year period. Each device periodically records WiFi scans and its GPS coordinates, reporting the collected data to us. We identify a number of challenges in using such data to build a WiFi localization database (e.g., mobility of access points), and introduce techniques to mitigate...

  20. Coal marketing in Asia: Opportunities and challenges

    International Nuclear Information System (INIS)

    Klingner, D.

    1996-01-01

    In Asia, coal currently accounts for over 40 percent of the fossil fuel used for commercial energy. This paper briefly surveys the forces that are likely to decide the future role coal will play as a prime source of energy in the vigorous economies of Asia. As Australia is well placed to profit from Asia's growing need for coal, the challenge to Australian coal suppliers is how to maximize its potential contribution. Four-fifths of all new coal fired electrical generating capacity in the world in the next decade will be located in Asia. Three-quarters of Australia's coal exports are to Asian customers and, conversely, 40 percent of Asian imports are from Australia. Australian coal suppliers have established ties and a depth of marketing experience in the region on which to build. However, pricing policies, and the emergence of the private power producers, together with environmental pressures, will present challenges for the future. (author). 1 fig

  1. The Colombian nuclear scenario: Challenges and opportunities

    Science.gov (United States)

    Martinez, Isabel

    2016-07-01

    In Colombia, the absence of nuclear-oriented policies based on technical knowledge, the closing of the Nuclear Affairs Institute (1956-1998), the association of the word "nuclear" with weapons, plus the country's last six decades of internal conflict and narcotraffic have discourage the technical, social and environmental nuclear advance. However, there are technical, social and economic national challenges that could be faced by the present nuclear technical capacities.

  2. Big Data, Big Opportunities, and Big Challenges.

    Science.gov (United States)

    Frelinger, Jeffrey A

    2015-11-01

    High-throughput assays have begun to revolutionize modern biology and medicine. The advent of cheap next-generation sequencing (NGS) has made it possible to interrogate cells and human populations as never before. Although this has allowed us to investigate the genetics, gene expression, and impacts of the microbiome, there remain both practical and conceptual challenges. These include data handling, storage, and statistical analysis, as well as an inherent problem of the analysis of heterogeneous cell populations.

  3. Pediatric dental sedation: challenges and opportunities

    OpenAIRE

    Nelson, Travis; Xu,Zheng

    2015-01-01

    Travis M Nelson, Zheng Xu Department of Pediatric Dentistry, University of Washington, Seattle, WA, USA Abstract: High levels of dental caries, challenging child behavior, and parent expectations support a need for sedation in pediatric dentistry. This paper reviews modern developments in pediatric sedation with a focus on implementing techniques to enhance success and patient safety. In recent years, sedation for dental procedures has been implicated in a disproportionate number of cases th...

  4. African Languages in a Digital Age: Challenges and Opportunities ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2010-05-01

    May 1, 2010 ... African Languages in a Digital Age: Challenges and Opportunities for Indigenous Language Computing. Book cover African ... Sign up now for IDRC news and views sent directly to your inbox each month. Subscribe.

  5. Status, challenges and marketing opportunities for canning navy ...

    African Journals Online (AJOL)

    Status, challenges and marketing opportunities for canning navy bean in Kenya. ... improve incomes of smallholder farmers in Kenya; its production and marketing has, however, stagnated. ... EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT

  6. Presentation: Overview of Water Reuse Challenges and Opportunities

    Science.gov (United States)

    This presentation, Overview of Water Reuse Challenges and Opportunities, was given at the STAR Human and Ecological Health Impacts Associated with Water Reuse and Conservation Practices Kick-off Meeting and Webinar held on Oct. 26-27, 2016.

  7. A hydrogen economy: opportunities and challenges

    International Nuclear Information System (INIS)

    Tseng, P.; Lee, J.; Friley, P.

    2005-01-01

    A hydrogen economy, the long-term goal of many nations, can potentially confer energy security, along with environmental and economic benefits. However, the transition from a conventional petroleum-based energy system to a hydrogen economy involves many uncertainties, such as the development of efficient fuel-cell technologies, problems in hydrogen production and its distribution infrastructure, and the response of petroleum markets. This study uses the US MARKAL model to simulate the impacts of hydrogen technologies on the US energy system and to identify potential impediments to a successful transition. Preliminary findings highlight possible market barriers facing the hydrogen economy, as well as opportunities in new R and D and product markets for bioproducts. Quantitative analysis also offers insights on policy options for promoting hydrogen technologies. (author)

  8. Challenges and Opportunities in Using Patient-Reported Outcomes in Quality Measurement in Rheumatology

    OpenAIRE

    Wahl, Elizabeth; Yazdany, Jinoos

    2016-01-01

    Use of Patient-reported outcome measures (PROs) in rheumatology research is widespread, but use of PRO data to evaluate the quality of rheumatologic care delivered is less well established. This article reviews the use of PROs in assessing healthcare quality, and highlights challenges and opportunities specific to their use in rheumatology quality measurement. We first explore other countries’ experiences collecting and evaluating national PRO data to assess quality of care. We describe the c...

  9. Opportunities and ethical challenges for the practice of medicine in the digital era

    OpenAIRE

    Herron, Patrick D.

    2015-01-01

    Technological advances have been a driving force in the practice of medicine. From the discovery of x-rays’ medical applications to the utilization of dialysis and surgical transplantation of organs, technology has presented new opportunities, and at times, ethical challenges for physicians. In recent years, the increased proliferation of social media tools has had a significant impact on how people engage with one another, and how they want to engage with their healthcare providers. Medical ...

  10. Exploring Challenges and Opportunities for Eco-Feedback Technology

    DEFF Research Database (Denmark)

    Verdezoto, Nervo

    This position paper explores challenges and opportunities for eco-feedback technology. Drawing on two design cases, I discuss the importance of supporting active participation as well as the articulation of work in everyday practices to facilitate reduction of consumption.......This position paper explores challenges and opportunities for eco-feedback technology. Drawing on two design cases, I discuss the importance of supporting active participation as well as the articulation of work in everyday practices to facilitate reduction of consumption....

  11. Diagnostics of ST Plasmas in NSTX: Challenges and Opportunities

    International Nuclear Information System (INIS)

    Johnson, D.; Efthimion, P.; Foley, J.; Jones, B.; Mazzucato, E.; Park, H.; Taylor, G.; Levinton, F.; Luhmann, N.

    2001-01-01

    This paper will highlight some of the challenges and opportunities present in the diagnosis of spherical torus (ST) plasmas on the National Spherical Torus Experiment (NSTX) and discuss the corresponding diagnostic development that is presently underway. After a brief description of diagnostic systems currently installed, examples of ST-specific diagnostic challenges will be highlighted, as will another case, where the ST configuration offers opportunities for new measurements

  12. Metabolomic Analysis in Brain Research: Opportunities & Challenges

    Directory of Open Access Journals (Sweden)

    Catherine G Vasilopoulou

    2016-05-01

    Full Text Available Metabolism being a fundamental part of molecular physiology, elucidating the structure and regulation of metabolic pathways is crucial for obtaining a comprehensive perspective of cellular function and understanding the underlying mechanisms of its dysfunction(s. Therefore, quantifying an accurate metabolic network activity map under various physiological conditions is among the major objectives of systems biology in the context of many biological applications. Especially for CNS, metabolic network activity analysis can substantially enhance our knowledge about the complex structure of the mammalian brain and the mechanisms of neurological disorders, leading to the design of effective therapeutic treatments. Metabolomics has emerged as the high-throughput quantitative analysis of the concentration profile of small molecular weight metabolites, which act as reactants and products in metabolic reactions and as regulatory molecules of proteins participating in many biological processes. Thus, the metabolic profile provides a metabolic activity fingerprint, through the simultaneous analysis of tens to hundreds of molecules of pathophysiological and pharmacological interest. The application of metabolomics is at its standardization phase in general, and the challenges for paving a standardized procedure are even more pronounced in brain studies. In this review, we support the value of metabolomics in brain research. Moreover, we demonstrate the challenges of designing and setting up a reliable brain metabolomic study, which, among other parameters, has to take into consideration the sex differentiation and the complexity of brain physiology manifested in its regional variation. We finally propose ways to overcome these challenges and design a study that produces reproducible and consistent results.

  13. Opportunities and Challenges in Neutrino Physics

    CERN Document Server

    Wojcicki, Stanley G

    2005-01-01

    During the last decade a number of key experiments revolutionized our ideas about neutrinos and gave the first indication of the physics beyond the Standard Model. This paper will summarize the current situation in neutrino physics and indicate the key questions that need to be addressed and resolved. Different approaches that are being proposed to address these issues will be described with a special emphasis on the technical challenges inherent in them. The paper will conclude with some more futuristic concepts in accelerator physics that are being discussed today as potential new powerful tools for the study of neutrinos in the future.

  14. Challenges and opportunities in social neuroscience

    Science.gov (United States)

    Cacioppo, John T.; Decety, Jean

    2010-01-01

    Social species are so characterized because they form organizations that extend beyond the individual. The goal of social neuroscience is to investigate the biological mechanisms that underlie these social structures, processes, and behavior and the influences between social and neural structures and processes. Such an endeavor is challenging because it necessitates the integration of multiple levels. Mapping across systems and levels (from genome to social groups and cultures) requires interdisciplinary expertise, comparative studies, innovative methods, and integrative conceptual analysis. Examples of how social neuroscience is contributing to our understanding of the functions of the brain and nervous system are described, and societal implications of social neuroscience are considered. PMID:21251011

  15. Internet of Things challenges and opportunities

    CERN Document Server

    2014-01-01

    Advancement in sensor technology, smart instrumentation, wireless sensor networks, miniaturization, RFID and information processing is helping towards the realization of Internet of Things (IoT). IoTs are finding applications in various area applications including environmental monitoring, intelligent buildings, smart grids and so on. This book provides design challenges of IoT, theory, various protocols, implementation issues and a few case study. The book will be very useful for postgraduate students and researchers to know from basics to implementation of IoT.

  16. Indian mutual fund industry: Opportunities and challenges

    Directory of Open Access Journals (Sweden)

    Jayant R. Kale

    2012-12-01

    Full Text Available This article presents an overview of the mutual fund industry in India and the reasons for its poor penetration, which includes lack of objective research. It benchmarks the industry globally, and raises key issues regarding the ownership and performance of mutual funds, the sensitivity of fund flows to performance, and the importance of regulation to its growth, all of which have been largely under researched in India. It then captures the views of leading practitioners on these and other issues, including the challenges posed by poor financial literacy, the equity culture in the country, and the weakly supportive regulatory environment.

  17. Adolescent Healthcare Brokering: Prevalence, Experience, Impact, and Opportunities

    Science.gov (United States)

    Banas, Jennifer R.; Wallis, Lisa C.; Ball, James W.; Gershon, Sarah

    2016-01-01

    Background: Limited health literacy disproportionately affects those with limited English proficiency (LEP). Parents with LEP might rely on their adolescent children to interpret health information. We call this "adolescent healthcare brokering." This study uncovers the prevalence of brokering, kinds of tasks, emotional and academic…

  18. Renewable energy in Pakistan: opportunities and challenges

    International Nuclear Information System (INIS)

    Mirza, I.A.; Khalil, M.S.

    2011-01-01

    Most of the countries around the world have realized that the key to attaining and maintaining prosperity and sovereignty is having independence and self-reliance in access to and subsequent use of energy. To address the global challenges, the energy system needs to undergo a transformation from fossil-fuels to renewable energy and energy efficient technologies. Pakistan has a huge potential for harnessing renewable energy and its share in the electricity mix has to be increased to achieve energy security. Security issues and circular debt in the country are the key challenges that need to be addressed to promote on-grid renewable energy through private sector. Around 38 % of the total Pakistani population remains without access to electricity. Fifty four per cent of the rural population currently has no access to electricity, forcing them to live a sub-standard life of poverty and social inequity. Microfinance and other innovative financial tools need to be evolved to promote rural electrification through renewable energies. (author)

  19. Cloud Computing: Opportunities and Challenges for Businesses

    Directory of Open Access Journals (Sweden)

    İbrahim Halil Seyrek

    2011-12-01

    Full Text Available Cloud computing represents a new approach for supplying and using information technology services. Considering its benefits for firms and the potential of changes that it may lead to, it is envisioned that cloud computing can be the most important innovation in information technology since the development of the internet. In this study, firstly, the development of cloud computing and related technologies are explained and classified by giving current application examples. Then the benefits of this new computing model for businesses are elaborated especially in terms of cost, flexibility and service quality. In spite of its benefits, cloud computing also poses some risks for firms, of which security is one of the most important, and there are some challenges in its implementation. This study points out the risks that companies should be wary about and some legal challenges related to cloud computing. Lastly, approaches that companies may take against cloud computing and different strategies that they may adopt are discussed and some recommendations are made

  20. Decadel climate prediction: challenges and opportunities

    International Nuclear Information System (INIS)

    Hurrell, J W

    2008-01-01

    The scientific understanding of climate change is now sufficiently clear to show that climate change from global warming is already upon us, and the rate of change as projected exceeds anything seen in nature in the past 10,000 years. Uncertainties remain, however, especially regarding how climate will change at regional and local scales where the signal of natural variability is large. Addressing many of these uncertainties will require a movement toward high resolution climate system predictions, with a blurring of the distinction between shorter-term predictions and longer-term climate projections. The key is the realization that climate system predictions, regardless of timescale, will require initialization of coupled general circulation models with best estimates of the current observed state of the atmosphere, oceans, cryosphere, and land surface. Formidable challenges exist: for instance, what is the best method of initialization given imperfect observations and systematic errors in models? What effect does initialization have on climate predictions? What predictions should be attempted, and how would they be verified? Despite such challenges, the unrealized predictability that resides in slowly evolving phenomena, such as ocean current systems, is of paramount importance for society to plan and adapt for the next few decades. Moreover, initialized climate predictions will require stronger collaboration with shared knowledge, infrastructure and technical capabilities among those in the weather and climate prediction communities. The potential benefits include improved understanding and predictions on all time scales

  1. Challenges and opportunities await natural gas industry

    International Nuclear Information System (INIS)

    Mohasseb, S.

    1998-01-01

    During the last two decades, the natural gas industry has gone through drastic changes. On one hand, deregulation and customer choice have been introduced to the industry. On the other hand, technological advances have resulted in substantial growth of available gas resources. In short, deregulation coupled with increased availability of supply has changed the way market participants interact with each other and which avenues they take to become leaders. Many new opportunities for entry into the market have also been created. As a result, the tide of competition has not only turned against the financially strong giants of the past, but it has also turned against new entrants who are fast, flexible and market driven. Natural gas utilities companies have responded by improving their operational efficiencies through process re-engineering, organizational re-alignment, restructuring and strategic alliances or mergers. Deregulation of the electricity industry is expected to increase competitive pressures on the natural gas industry, thus causing even more of a decrease in natural gas prices. In the future, natural gas utilities must be able to improve their effectiveness by accurately forecasting demand and optimizing their own supply and delivery systems in such a way that costs are minimized without compromising the reliability of supply. The new frontier of competitiveness will ensure that structural changes in the industry are characterized by an effective management of the supply-demand relationship and the optimization of risks inherently a part of gas delivery

  2. Challenges and opportunities in laboratory plasma astrophysics

    Science.gov (United States)

    Drake, R. Paul

    2017-06-01

    We are in a period of explosive success and opportunity in the laboratory study of plasma phenomena that are relevant to astrophysics. In this talk I will share with you several areas in which recent work, often foreshadowed 20 or 30 years ago, has produced dramatic initial success with prospects for much more. To begin, the talk will provide a brief look at the types of devices used and the regimes they access, showing how they span many orders of magnitude in parameters of interest. It will then illustrate the types of work one can do with laboratory plasmas that are relevant to astrophysics, which range from direct measurement of material properties to the production of scaled models of certain dynamics to the pursuit of complementary understanding. Examples will be drawn from the flow of energy and momentum in astrophysics, the formation and structure of astrophysical systems, and magnetization and its consequences. I hope to include some discussion of collisionless shocks, very dense plasmas, work relevant to the end of the Dark Ages, reconnection, and dynamos. The talk will conclude by highlighting some topics where it seems that we may be on the verge of exciting new progress.The originators of work discussed, and collaborators and funding sources when appropriate, will be included in the talk.

  3. Vehicular Internet: Security & Privacy Challenges and Opportunities

    Directory of Open Access Journals (Sweden)

    Kamran Zaidi

    2015-07-01

    Full Text Available The vehicular internet will drive the future of vehicular technology and intelligent transportation systems (ITS. Whether it is road safety, infotainment, or driver-less cars, the vehicular internet will lay the foundation for the future of road travel. Governments and companies are pursuing driver-less vehicles as they are considered to be more reliable than humans and, therefore, safer. The vehicles today are not just a means of transportation but are also equipped with a wide range of sensors that provide valuable data. If vehicles are enabled to share data that they collect with other vehicles or authorities for decision-making and safer driving, they thereby form a vehicular network. However, there is a lot at stake in vehicular networks if they are compromised. With the stakes so high, it is imperative that the vehicular networks are secured and made resilient to any attack or attempt that may have serious consequences. The vehicular internet can also be the target of a cyber attack, which can be devastating. In this paper, the opportunities that the vehicular internet offers are presented and then various security and privacy aspects are discussed and some solutions are presented.

  4. Nanomanufacturing and sustainability: opportunities and challenges

    International Nuclear Information System (INIS)

    Busnaina, Ahmed A.; Mead, Joey; Isaacs, Jacqueline; Somu, Sivasubramanian

    2013-01-01

    New nanomanufacturing technologies, although still in research labs, present a great opportunity to drastically reduce the cost of making nanostructures on a large scale and at high-rates. Such new bottom-up directed assembly-based approaches involve adding materials selectively thereby both reducing waste and the number of required processes. Directed assembly-based processes are conducted at room pressure and temperatures which significantly reduces the cost of nanomanufacturing equipment and tools, ensuring long-term sustainability by reducing energy, consumables, and waste costs. This paradigm shift in nanomanufacturing will unleash not only a wave of creativity in sustainable nanomanufacturing but lessons learnt along the way can be used in various other sectors. Along with the exquisite technological promise that nanotechnology holds, nano-enabled products are heralded as a means for energy and resource reduction, resulting in potential manufacturing cost reductions and further, for potential improvements to environmental remediation. Sustainable nanomanufacturing will, by dramatically lowering current nanomanufacturing barriers, spur innovation, and the creation of entirely new industries by leveling the playing and ultimately leading to the democratization of nanomanufacturing

  5. Nanomanufacturing and sustainability: opportunities and challenges

    Energy Technology Data Exchange (ETDEWEB)

    Busnaina, Ahmed A., E-mail: BUSNAINA@COE.NEU.EDU [Northeastern University, NSF Nanoscale Science and Engineering Center for High-rate Nanomanufacturing (United States); Mead, Joey [University of Massachusetts Lowell (United States); Isaacs, Jacqueline; Somu, Sivasubramanian [Northeastern University, NSF Nanoscale Science and Engineering Center for High-rate Nanomanufacturing (United States)

    2013-10-15

    New nanomanufacturing technologies, although still in research labs, present a great opportunity to drastically reduce the cost of making nanostructures on a large scale and at high-rates. Such new bottom-up directed assembly-based approaches involve adding materials selectively thereby both reducing waste and the number of required processes. Directed assembly-based processes are conducted at room pressure and temperatures which significantly reduces the cost of nanomanufacturing equipment and tools, ensuring long-term sustainability by reducing energy, consumables, and waste costs. This paradigm shift in nanomanufacturing will unleash not only a wave of creativity in sustainable nanomanufacturing but lessons learnt along the way can be used in various other sectors. Along with the exquisite technological promise that nanotechnology holds, nano-enabled products are heralded as a means for energy and resource reduction, resulting in potential manufacturing cost reductions and further, for potential improvements to environmental remediation. Sustainable nanomanufacturing will, by dramatically lowering current nanomanufacturing barriers, spur innovation, and the creation of entirely new industries by leveling the playing and ultimately leading to the democratization of nanomanufacturing.

  6. Professional development and leadership training opportunities for healthcare professionals.

    Science.gov (United States)

    Sonnino, Roberta E

    2013-11-01

    Formal leadership training is a relatively recent addition to the educational armamentarium of the health care executive. Leadership training opportunities for physicians, surgeons, and scientists have gradually appeared over the past 15 to 20 years, but information about them has been scant, with few comprehensive reviews made available to the community at large. This article describes the major opportunities available to obtain formal and informal leadership training for careers in medical school administration. Programs that are specifically targeted to women are described in detail. Information was obtained from the author's direct knowledge, direct communication with the leadership of each program, and the Web site of each sponsoring organization, when available. Many opportunities for leadership training are now available to surgeons, with several specifically designed for women. The author strongly encourages surgeons to avail themselves of these opportunities, as both anecdotal information and published data suggest that these programs are highly effective in enhancing leadership careers. Copyright © 2013 Elsevier Inc. All rights reserved.

  7. Challenges and Opportunities for Harmonizing Research Methodology

    DEFF Research Database (Denmark)

    van Hees, V. T.; Thaler-Kall, K.; Wolf, K. H.

    2016-01-01

    Objectives: Raw accelerometry is increasingly being used in physical activity research, but diversity in sensor design, attachment and signal processing challenges the comparability of research results. Therefore, efforts are needed to harmonize the methodology. In this article we reflect on how...... increased methodological harmonization may be achieved. Methods: The authors of this work convened for a two-day workshop (March 2014) themed on methodological harmonization of raw accelerometry. The discussions at the workshop were used as a basis for this review. Results: Key stakeholders were identified...... as manufacturers, method developers, method users (application), publishers, and funders. To facilitate methodological harmonization in raw accelerometry the following action points were proposed: i) Manufacturers are encouraged to provide a detailed specification of their sensors, ii) Each fundamental step...

  8. Complex plasmas scientific challenges and technological opportunities

    CERN Document Server

    Lopez, Jose; Becker, Kurt; Thomsen, Hauke

    2014-01-01

    This book provides the reader with an introduction to the physics of complex plasmas, a discussion of the specific scientific and technical challenges they present, and an overview of their potential technological applications. Complex plasmas differ from conventional high-temperature plasmas in several ways: they may contain additional species, including nanometer- to micrometer-sized particles, negative ions, molecules and radicals, and they may exhibit strong correlations or quantum effects. This book introduces the classical and quantum mechanical approaches used to describe and simulate complex plasmas. It also covers some key experimental techniques used in the analysis of these plasmas, including calorimetric probe methods, IR absorption techniques and X-ray absorption spectroscopy. The final part of the book reviews the emerging applications of microcavity and microchannel plasmas, the synthesis and assembly of nanomaterials through plasma electrochemistry, the large-scale generation of ozone using mi...

  9. Sustainable Tourism: Progress Challenges and Opportunities

    DEFF Research Database (Denmark)

    Budeanu, Adriana; Miller, Graham; Moscardo, Gianna

    2016-01-01

    The term sustainable tourism emerged in the late 1980s and has become firmly established in both tourism policies and strategies and tourism research (Hall, 2011). After more than 25 years of attention it is timely to consider the state of research and practice in sustainable tourism. This special...... volume was established with exactly that goal in mind and this introduction seeks to set the context for this critical examination and reflection on sustainable tourism. Another objective of this introduction was to briefly describe the range of contributions selected for this SV. The articles...... are organised into four thematic areas of research: community stakeholders' perspectives and business approaches to sustainability in tourism, cultural responses, and methodological challenges related to sustainability. The articles shine a light on issues of importance within sustainable tourism, and in so...

  10. Ammonia for hydrogen storage: challenges and opportunities

    DEFF Research Database (Denmark)

    Klerke, Asbjørn; Christensen, Claus H.; Nørskov, Jens Kehlet

    2008-01-01

    The possibility of using ammonia as a hydrogen carrier is discussed. Compared to other hydrogen storage materials, ammonia has the advantages of a high hydrogen density, a well-developed technology for synthesis and distribution, and easy catalytic decomposition. Compared to hydrocarbons...... and alcohols, it has the advantage that there is no CO2 emission at the end user. The drawbacks are mainly the toxicity of liquid ammonia and the problems related to trace amounts of ammonia in the hydrogen after decomposition. Storage of ammonia in metal ammine salts is discussed, and it is shown...... that this maintains the high volumetric hydrogen density while alleviating the problems of handling the ammonia. Some of the remaining challenges for research in ammonia as a hydrogen carrier are outlined....

  11. Ovarian cancer immunotherapy: opportunities, progresses and challenges

    Directory of Open Access Journals (Sweden)

    Stevens Richard

    2010-02-01

    Full Text Available Abstract Due to the low survival rates from invasive ovarian cancer, new effective treatment modalities are urgently needed. Compelling evidence indicates that the immune response against ovarian cancer may play an important role in controlling this disease. We herein summarize multiple immune-based strategies that have been proposed and tested for potential therapeutic benefit against advanced stage ovarian cancer. We will examine the evidence for the premise that an effective therapeutic vaccine against ovarian cancer is useful not only for inducing remission of the disease but also for preventing disease relapse. We will also highlight the questions and challenges in the development of ovarian cancer vaccines, and critically discuss the limitations of some of the existing immunotherapeutic strategies. Finally, we will summarize our own experience on the use of patient-specific tumor-derived heat shock protein-peptide complex for the treatment of advanced ovarian cancer.

  12. Nanomaterials and Water Purification: Opportunities and Challenges

    Science.gov (United States)

    Savage, Nora; Diallo, Mamadou S.

    2005-10-01

    Advances in nanoscale science and engineering suggest that many of the current problems involving water quality could be resolved or greatly ameliorated using nanosorbents, nanocatalysts, bioactive nanoparticles, nanostructured catalytic membranes and nanoparticle enhanced filtration among other products and processes resulting from the development of nanotechnology. Innovations in the development of novel technologies to desalinate water are among the most exciting and promising. Additionally, nanotechnology-derived products that reduce the concentrations of toxic compounds to sub-ppb levels can assist in the attainment of water quality standards and health advisories. This article gives an overview of the use of nanomaterials in water purification. We highlight recent advances on the development of novel nanoscale materials and processes for treatment of surface water, groundwater and industrial wastewater contaminated by toxic metal ions, radionuclides, organic and inorganic solutes, bacteria and viruses. In addition, we discuss some challenges associated with the development of cost effective and environmentally acceptable functional nanomaterials for water purification.

  13. Nanomaterials and Water Purification: Opportunities and Challenges

    International Nuclear Information System (INIS)

    Savage, Nora; Diallo, Mamadou S.

    2005-01-01

    Advances in nanoscale science and engineering suggest that many of the current problems involving water quality could be resolved or greatly ameliorated using nanosorbents, nanocatalysts, bioactive nanoparticles, nanostructured catalytic membranes and nanoparticle enhanced filtration among other products and processes resulting from the development of nanotechnology. Innovations in the development of novel technologies to desalinate water are among the most exciting and promising. Additionally, nanotechnology-derived products that reduce the concentrations of toxic compounds to sub-ppb levels can assist in the attainment of water quality standards and health advisories. This article gives an overview of the use of nanomaterials in water purification. We highlight recent advances on the development of novel nanoscale materials and processes for treatment of surface water, groundwater and industrial wastewater contaminated by toxic metal ions, radionuclides, organic and inorganic solutes, bacteria and viruses. In addition, we discuss some challenges associated with the development of cost effective and environmentally acceptable functional nanomaterials for water purification

  14. Nuclear Hybrid Energy Systems: Challenges and Opportunities

    Energy Technology Data Exchange (ETDEWEB)

    P. Sabharwall; S.B. Sitton; S.J. Yoon; C. Stoots

    2014-07-01

    With growing demand of energy and costs of the fossil fuels, coupled with the environmental concerns have resulted in an increased interest in alternative energy sources. Nuclear hybrid energy systems (NHES) are being considered which incorporates renewable energy sources such as solar and wind energy combined with nuclear reactor and energy storage to meet the peak hours demand imposed on the grid, along with providing process heat for other potential industrial applications. This concept could potentially satisfy various energy demands and improve reliability, robustness and resilience for the entire system as a whole, along with economic and net efficiency gains. This paper provides a brief understanding of potential NHES system and architecture along with the challenges

  15. Wildfire Risk Management: Challenges and Opportunities

    Science.gov (United States)

    Thompson, M.; Calkin, D. E.; Hand, M. S.; Kreitler, J.

    2014-12-01

    In this presentation we address federal wildfire risk management largely through the lens of economics, targeting questions related to costs, effectiveness, efficiency, and tradeoffs. Beyond risks to resources and assets such as wildlife habitat, watersheds, and homes, wildfires present financial risk and budgetary instability for federal wildfire management agencies due to highly variable annual suppression costs. Despite its variability, the costs of wildfire management have continued to escalate and account for an ever-growing share of overall agency budgets, compromising abilities to attain other objectives related to forest health, recreation, timber management, etc. Trends associated with a changing climate and human expansion into fire-prone areas could lead to additional suppression costs in the future, only further highlighting the need for an ability to evaluate economic tradeoffs in investments across the wildfire management spectrum. Critically, these economic analyses need to accurately capture the complex spatial and stochastic aspects of wildfire, the inherent uncertainty associated with monetizing environmental impacts of wildfire, the costs and effectiveness of alternative management policies, and linkages between pre-fire investments and active incident management. Investing in hazardous fuels reduction and forest restoration in particular is a major policy lever for pre-fire risk mitigation, and will be a primary focus of our presentation. Evaluating alternative fuel management and suppression policies could provide opportunities for significant efficiency improvements in the development of risk-informed management fire management strategies. Better understanding tradeoffs of fire impacts and costs can help inform policy questions such as how much of the landscape to treat and how to balance investments in treating new areas versus maintaining previous investments. We will summarize current data needs, knowledge gaps, and other factors

  16. The ASME Code today -- Challenges, threats, opportunities

    International Nuclear Information System (INIS)

    Canonico, D.A.

    1995-01-01

    Since its modest beginning as a single volume in 1914 the ASME Code, or some of its parts, is recognized today in 48 of the United States and all providence's of Canada. The ASME Code today is composed of 25 books including two Code Case books. These books cover the new construction of boilers and pressure vessels and the new construction and In-Service-Inspection of Nuclear Power Plant components. The ASME accredits all manufacturers of boilers and pressure vessels built to the ASME Code. There are approximately 7650 symbol stamps issued throughout the world. Over 23% of the symbol stamps have been issued outside the USA and Canada. The challenge to the ASME Code is to be accepted as the world standard for pressure boundary components. There are activities underway to achieve that goal. The ASME Code is being revised to make it a more friendly document to entities outside of North America. To achieve that end there are specific tasks underway which are described here

  17. Market opportunities and challenges for oil sands

    International Nuclear Information System (INIS)

    Wise, T.H.

    2004-01-01

    The use of Alberta bitumen as a clean fuel depends on upgrading, transportation, and refining processes. Forecasts show that oil sands production, which includes synthetic crude oil (SCO), will surpass declining conventional production from the Western Canada Sedimentary Basin. The challenges facing the oils sands processing industry include: crude oil prices which affect the producer's market; market expansion options; diluent availability/cost; supply cost competitiveness; and, regional processing. The common market issues include light/heavy crude prices, oil sands crude qualities, prices of oil sands crudes, pipeline infrastructure, and competitive supplies. The issues facing the refiners are: refining margins, security of crude supply, refined product quality, and competitive product supply. It was noted that Alberta must retain or increase its share of the Midwest market. The market expansion options were reviewed for both downstream (refining) and upstream (upgrading) operations. New pipeline capacity is needed to reach more distant markets such as Southern Midwest, Washington, and California. The market is nearly saturated for Canada's heavy oil supply. More upgrading will be required as bitumen production increases. Market growth is still possible for Canada's SCO but according to forecasts, the market could also become saturated. To increase demand and allow supplies to grow, SCO prices may fall below light crude prices. It was noted that a balance must be achieved in order for producers to increase production and for refiner/upgraders to expand their conversion capacity. 13 figs

  18. Communicating actionable nutrition messages: challenges and opportunities.

    Science.gov (United States)

    Goldberg, Jeanne P; Sliwa, Sarah A

    2011-02-01

    As long as health communications have existed in the USA, Americans have faced the task of sorting the agenda of the source from the advice it provides. That task has become more complicated as advances in the science of nutrition and the technology used to present it have heightened the complexity of nutrition communications. Getting consumers to adopt a healthier diet has been a protracted undertaking with limited successes along the way. The obesity epidemic has added urgency to this discourse: not only do we need to eat better, but most of us also need to eat less. This paper reviews the dynamics that have made the communication of accurate and actionable health behaviour information an ongoing challenge, and outlines strategies for moving ahead. It considers the interplay of four sets of factors: the evolutionary nature of the science on which recommendations are based; the many sources of communication about that science; the agendas or motivations of each source; and finally the multifaceted nature of consumers, the recipients of these communications. Communication alone has not been, and will not be, sufficient for consumers to adopt the behavioural changes endorsed by experts. Broad environmental interventions coupled with individual skills development will need to be part of the process. Ultimately, it is the consumer who decides what is for dinner. Media literacy will play a critical role in building consumer efficacy in sorting fact from fiction in order to select food for a healthful diet.

  19. Aging in Lebanon: Challenges and Opportunities.

    Science.gov (United States)

    Abdulrahim, Sawsan; Ajrouch, Kristine J; Antonucci, Toni C

    2015-08-01

    This spotlight offers a unique window into factors affecting aging in Lebanon. As a bridge between east and west, both geographically and culturally, Lebanon has the fastest growing older adult population in the Arab region, but few societal resources to address its needs. In a country with a history of political instability and war, but also a culture with strong family values, aging adults in Lebanon are vulnerable in some ways and advantaged in others. Outmigration of youth is an important determinant of the wellbeing of the elderly. While often advantaged by remittances sent by their children, older Lebanese adults have less access to instrumental social and personal support previously provided by young adults in the family. How Lebanon manages these challenges is likely to foreshadow the future aging experience for much of the Arab region. © The Author 2014. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  20. Russian electricity reform. Emerging challenges and opportunities

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    The Russian Government is pursuing a strategy of very high economic growth, with the objective of doubling gross domestic product in ten years. It recognises the central role the electricity sector has to play to achieve this target and has embarked on a highly ambitious program of electricity reform. If it is to succeed, the reform program will have to create market structures, market rules and a regulatory framework that will foster competitive wholesale and retail electricity markets. At the same time, it will have to deal with sensitive social issues related to tariff rebalancing and the removal of cross subsidies. Only competitive markets based on transparent prices that reflect costs can deliver the efficient, reliable and internationally competitive performance needed to meet the government's economic targets. Such markets are essential to attract new investment that will be required to ensure security of electricity supply after 2010. This book focuses on key aspects of the proposed reform that could have an important bearing on its success. It also raises concerns as to the pace of reform in related areas, such as the need for complementary reforms in the Russian natural gas sector. The IEA commends the Russian Government on its efforts to embrace this electricity reform - a key element critical to meeting the challenges ahead in terms of its economic growth and energy security. 17 figs., 10 tabs., 3 maps.

  1. Pharmacogenetics of warfarin: challenges and opportunities

    Science.gov (United States)

    Ta Michael Lee, Ming; Klein, Teri E

    2014-01-01

    Since the introduction in the 1950s, warfarin has become the commonly used oral anticoagulant for the prevention of thromboembolism in patients with deep vein thrombosis, atrial fibrillation or prosthetic heart valve replacement. Warfarin is highly efficacious; however, achieving the desired anticoagulation is difficult because of its narrow therapeutic window and highly variable dose response among individuals. Bleeding is often associated with overdose of warfarin. There is overwhelming evidence that an individual's warfarin maintenance is associated with clinical factors and genetic variations, most notably polymorphisms in cytochrome P450 2C9 and vitamin K epoxide reductase subunit 1. Numerous dose-prediction algorithms incorporating both genetic and clinical factors have been developed and tested clinically. However, results from major clinical trials are not available yet. This review aims to provide an overview of the field of warfarin which includes information about the drug, genetics of warfarin dose requirements, dosing algorithms developed and the challenges for the clinical implementation of warfarin pharmacogenetics. PMID:23657428

  2. Pediatric dental sedation: challenges and opportunities.

    Science.gov (United States)

    Nelson, Travis M; Xu, Zheng

    2015-01-01

    High levels of dental caries, challenging child behavior, and parent expectations support a need for sedation in pediatric dentistry. This paper reviews modern developments in pediatric sedation with a focus on implementing techniques to enhance success and patient safety. In recent years, sedation for dental procedures has been implicated in a disproportionate number of cases that resulted in death or permanent neurologic damage. The youngest children and those with more complicated medical backgrounds appear to be at greatest risk. To reduce complications, practitioners and regulatory bodies have supported a renewed focus on health care quality and safety. Implementation of high fidelity simulation training and improvements in patient monitoring, including end-tidal carbon dioxide, are becoming recognized as a new standard for sedated patients in dental offices and health care facilities. Safe and appropriate case selection and appropriate dosing for overweight children is also paramount. Oral sedation has been the mainstay of pediatric dental sedation; however, today practitioners are administering modern drugs in new ways with high levels of success. Employing contemporary transmucosal administration devices increases patient acceptance and sedation predictability. While recently there have been many positive developments in sedation technology, it is now thought that medications used in sedation and anesthesia may have adverse effects on the developing brain. The evidence for this is not definitive, but we suggest that practitioners recognize this developing area and counsel patients accordingly. Finally, there is a clear trend of increased use of ambulatory anesthesia services for pediatric dentistry. Today, parents and practitioners have become accustomed to children receiving general anesthesia in the outpatient setting. As a result of these changes, it is possible that dental providers will abandon the practice of personally administering large amounts of

  3. Pediatric dental sedation: challenges and opportunities

    Directory of Open Access Journals (Sweden)

    Nelson TM

    2015-08-01

    Full Text Available Travis M Nelson, Zheng Xu Department of Pediatric Dentistry, University of Washington, Seattle, WA, USA Abstract: High levels of dental caries, challenging child behavior, and parent expectations support a need for sedation in pediatric dentistry. This paper reviews modern developments in pediatric sedation with a focus on implementing techniques to enhance success and patient safety. In recent years, sedation for dental procedures has been implicated in a disproportionate number of cases that resulted in death or permanent neurologic damage. The youngest children and those with more complicated medical backgrounds appear to be at greatest risk. To reduce complications, practitioners and regulatory bodies have supported a renewed focus on health care quality and safety. Implementation of high fidelity simulation training and improvements in patient monitoring, including end-tidal carbon dioxide, are becoming recognized as a new standard for sedated patients in dental offices and health care facilities. Safe and appropriate case selection and appropriate dosing for overweight children is also paramount. Oral sedation has been the mainstay of pediatric dental sedation; however, today practitioners are administering modern drugs in new ways with high levels of success. Employing contemporary transmucosal administration devices increases patient acceptance and sedation predictability. While recently there have been many positive developments in sedation technology, it is now thought that medications used in sedation and anesthesia may have adverse effects on the developing brain. The evidence for this is not definitive, but we suggest that practitioners recognize this developing area and counsel patients accordingly. Finally, there is a clear trend of increased use of ambulatory anesthesia services for pediatric dentistry. Today, parents and practitioners have become accustomed to children receiving general anesthesia in the outpatient setting. As a

  4. Big Data Provenance: Challenges, State of the Art and Opportunities

    OpenAIRE

    Wang, Jianwu; Crawl, Daniel; Purawat, Shweta; Nguyen, Mai; Altintas, Ilkay

    2015-01-01

    Ability to track provenance is a key feature of scientific workflows to support data lineage and reproducibility. The challenges that are introduced by the volume, variety and velocity of Big Data, also pose related challenges for provenance and quality of Big Data, defined as veracity. The increasing size and variety of distributed Big Data provenance information bring new technical challenges and opportunities throughout the provenance lifecycle including recording, querying, sharing and ut...

  5. Healthcare.gov: Opportunity out of Disaster. Teaching Case

    Science.gov (United States)

    Cundiff, Jacob; McCallum, Taylor; Rich, Andrew; Truax, Michael; Ward, Tamara; Havelka, Douglas

    2015-01-01

    The launch of HealthCare.gov, the website of the Affordable Care Act (AKA Obamacare), was a major public relations disaster for the Obama administration. This case examines some of the factors that contributed to the failure of the launch and then details how Optum, an information technology service provider, considered the opportunity provided by…

  6. Cultural challenges to oral healthcare implementation in elders.

    Science.gov (United States)

    Lo, Edward C M; Tan, Hai P

    2014-02-01

    For successful implementation of oral healthcare services for elders, there is a need to understand and respond to their oral health beliefs, perceived needs and preferred type of care services, all of which are shaped by their cultural beliefs and values. This poses challenges to oral healthcare providers, especially when serving a diverse elderly population with people coming from different cultural backgrounds. The general principles of oral healthcare provision and their adaptation to serve culturally diverse elderly populations are discussed. The oral health beliefs and behaviours of Chinese, an ethnic group that can be found in many countries across the world, are highlighted and used as examples. Chinese elders generally attach a higher value to the physical functions than to the appearance of their dentition and prefer to use traditional self-care methods to deal with their oral health problems rather than to seek professional services. There is need to incorporate into the training of oral healthcare providers the competence to adapt their services to the beliefs and practices of culturally diverse elderly population groups in different settings. © 2014 John Wiley & Sons A/S and The Gerodontology Society. Published by John Wiley & Sons Ltd.

  7. Billboard advertising: an avenue for communicating healthcare information and opportunities to disadvantaged populations.

    Science.gov (United States)

    Elrod, James K; Fortenberry, John L

    2017-12-13

    Healthcare communications directed toward the disadvantaged have the potential to elevate the health status of these underprivileged and highly-challenged individuals. From conveying advice which encourages healthy lifestyles to communicating the location and availability of various medical resources, healthier lives and communities can be realized. Success on this front first requires establishing an effective communications link, something that is made more difficult as communications options available to the disadvantaged are more limited than those available to advantaged populations. One avenue which shows exceptional promise for successfully engaging the disadvantaged is that of billboard advertising. Willis-Knighton Health System's experiences and insights indicate that the characteristics and qualities of billboards, paired with the environmental circumstances typically faced by the less fortunate, create unique combinations which amplify consumption of billboard advertising content. Further, research suggests that the less privileged place greater reliance on the medium than do their more privileged counterparts, escalating the value and impact potential of billboard advertising directed toward the disadvantaged. Given the value afforded by health and wellness information successfully reaching the disadvantaged, opportunities to better distribute content to targeted audiences could very well improve community health. Billboard advertising appears to be well suited to engage the less fortunate, providing a productive pathway for the conveyance of helpful, supportive details, yielding healthier populations, enhanced opportunities, and better communities.

  8. Seeking opportunities abroad : the challenges for small companies

    International Nuclear Information System (INIS)

    Cej, R.P.

    1999-01-01

    The unique challenges facing small companies seeking opportunities in world hydrocarbon trading are discussed. The paper emphasizes how the global infrastructure of the industry has changed and describes what it takes for small companies to compete for opportunities in a global market. The biggest driver re-shaping the energy sector is the pace of global development led by the Asia-Pacific region. Canada's energy sector is well into the challenges created by market liberalization. Canada has evolved into a low cost energy supply and must remain so to support the competitiveness of other industry sectors. Overall, opportunities abroad for small companies are good. Commitment to the long haul, acquiring an understanding for the culture, the politics, and the way business is done in the country in question, careful attention to estimating the size and staying power needed to manage the opportunity, and avoiding cutting corners, or spreading oneself too thinly, are crucial to success

  9. Home care services for sick children: Healthcare professionals' conceptions of challenges and facilitators.

    Science.gov (United States)

    Castor, Charlotte; Hallström, Inger; Hansson, Helena; Landgren, Kajsa

    2017-09-01

    To explore healthcare professionals' conceptions of caring for sick children in home care services. Families often prefer home care to hospital care, and the number of home care services for children is increasing. Caring for children at home has been recognised as challenging for healthcare professionals in home care services used to providing care predominately for adults. An inductive qualitative design. Seven focus group interviews were performed with 36 healthcare professionals from multidisciplinary home care services. Data were analysed stepwise using a phenomenographic analysis. Three description categories emerged: "A challenging opportunity", "A child perspective", and "Re-organise in accordance with new prerequisites." Providing home care services for children was conceived to evoke both professional and personal challenges such as feelings of inadequacy and fear and professional growth such as increased competence and satisfaction. Conceptions of whether the home or the hospital was the best place for care differed. Adapting to the child's care was conceived as important. Cooperation with paediatric departments and a well-functioning team work were important organisational aspects. Providing home care for children was a challenging but rewarding task for healthcare professionals used to care for adults. To provide care with a child perspective was experienced as important even though there were conflicting conceptions of how this should be done. Close cooperation with paediatric departments and teamwork were prerequisites that make up for the low number of paediatric patients and facilitate confidence and competence. A sufficient number of referred children and enabling healthcare professionals to be part of the re-organising and implementation processes might facilitate the home care services for sick children. Enough time and good teamwork must be emphasised. Early referrals, continuous cooperation with paediatric clinics complemented with

  10. Modeling and Management of Big Data: Challenges and opportunities

    OpenAIRE

    Gil, David; Song, Il-Yeol

    2016-01-01

    The term Big Data denotes huge-volume, complex, rapid growing datasets with numerous, autonomous and independent sources. In these new circumstances Big Data bring many attractive opportunities; however, good opportunities are always followed by challenges, such as modelling, new paradigms, novel architectures that require original approaches to address data complexities. The purpose of this special issue on Modeling and Management of Big Data is to discuss research and experience in modellin...

  11. Challenges and opportunities in synthetic biology for chemical engineers.

    Science.gov (United States)

    Luo, Yunzi; Lee, Jung-Kul; Zhao, Huimin

    2013-11-15

    Synthetic biology provides numerous great opportunities for chemical engineers in the development of new processes for large-scale production of biofuels, value-added chemicals, and protein therapeutics. However, challenges across all scales abound. In particular, the modularization and standardization of the components in a biological system, so-called biological parts, remain the biggest obstacle in synthetic biology. In this perspective, we will discuss the main challenges and opportunities in the rapidly growing synthetic biology field and the important roles that chemical engineers can play in its advancement.

  12. Challenges and opportunities in synthetic biology for chemical engineers

    Science.gov (United States)

    Luo, Yunzi; Lee, Jung-Kul; Zhao, Huimin

    2012-01-01

    Synthetic biology provides numerous great opportunities for chemical engineers in the development of new processes for large-scale production of biofuels, value-added chemicals, and protein therapeutics. However, challenges across all scales abound. In particular, the modularization and standardization of the components in a biological system, so-called biological parts, remain the biggest obstacle in synthetic biology. In this perspective, we will discuss the main challenges and opportunities in the rapidly growing synthetic biology field and the important roles that chemical engineers can play in its advancement. PMID:24222925

  13. Big Data Provenance: Challenges, State of the Art and Opportunities.

    Science.gov (United States)

    Wang, Jianwu; Crawl, Daniel; Purawat, Shweta; Nguyen, Mai; Altintas, Ilkay

    2015-01-01

    Ability to track provenance is a key feature of scientific workflows to support data lineage and reproducibility. The challenges that are introduced by the volume, variety and velocity of Big Data, also pose related challenges for provenance and quality of Big Data, defined as veracity. The increasing size and variety of distributed Big Data provenance information bring new technical challenges and opportunities throughout the provenance lifecycle including recording, querying, sharing and utilization. This paper discusses the challenges and opportunities of Big Data provenance related to the veracity of the datasets themselves and the provenance of the analytical processes that analyze these datasets. It also explains our current efforts towards tracking and utilizing Big Data provenance using workflows as a programming model to analyze Big Data.

  14. Urban Big Data and Sustainable Development Goals: Challenges and Opportunities

    OpenAIRE

    Kharrazi, A.; Qin, H.; Zhang, Y.

    2016-01-01

    Cities are perhaps one of the most challenging and yet enabling arenas for sustainable development goals. The Sustainable Development Goals (SDGs) emphasize the need to monitor each goal through objective targets and indicators based on common denominators in the ability of countries to collect and maintain relevant standardized data. While this approach is aimed at harmonizing the SDGs at the national level, it presents unique challenges and opportunities for the development of innovative ur...

  15. Lone Actors: Challenges and Opportunities for Countering Violent Extremism

    NARCIS (Netherlands)

    Spaaij, R.; Richman, A.; Sharan, Y.

    2015-01-01

    This paper explores some of the key challenges and opportunities concerning the prevention and control of lone actor terrorism. It is argued that lone actors do not operate in a social vacuum and that the interaction points between lone actors and their social environments can render lone actors

  16. Streaming Audio and Video: New Challenges and Opportunities for Museums.

    Science.gov (United States)

    Spadaccini, Jim

    Streaming audio and video present new challenges and opportunities for museums. Streaming media is easier to author and deliver to Internet audiences than ever before; digital video editing is commonplace now that the tools--computers, digital video cameras, and hard drives--are so affordable; the cost of serving video files across the Internet…

  17. Career challenges and opportunities in the global chemistry enterprise

    Science.gov (United States)

    This article serves as an overview of the various career challenges and opportunities faced by chemistry professionals in the 21st century in the global chemistry enterprise. One goal is to highlight a broad spectrum of career paths, including non-traditional careers, and to showcase examples of ch...

  18. Human Resource Development in Mauritius: Context, Challenges and Opportunities

    Science.gov (United States)

    Garavan, Thomas N.; Neeliah, Harris; Auckloo, Raj; Ragaven, Raj

    2016-01-01

    Purpose: The purpose of this paper is to explore human resource development (HRD) in Mauritius and the challenges and opportunities faced by organisations in different sectors in adopting HRD practices. Findings: This special issue presents four papers that explore dimensions of HRD in public sector, small- and medium-sized enterprises (SMEs) and…

  19. Workplace Diversity and Public Policy: Challenges and Opportunities for Psychology

    Science.gov (United States)

    Fassinger, Ruth E.

    2008-01-01

    This article outlines both challenges and opportunities for psychology of issues related to diversity in education and work. For the purposes of this discussion, "diverse" populations include four groups currently marginalized and disadvantaged in the U.S. workplace: women, people of color, sexual minorities, and people with disabilities. An…

  20. Challenges and Opportunities for International Students in Graduate Education

    Science.gov (United States)

    Liang, Xinya

    2015-01-01

    International students pursuing graduate education in U.S. institutes have been rapidly increasing in recent years. Students from all over the world remarkably contribute to the advancement of U.S. economy and technology. This article addresses the challenges and opportunities international students face during and after graduate education. The…

  1. Current opportunities and challenges in skeletal muscle tissue engineering

    NARCIS (Netherlands)

    Koning, Merel; Harmsen, Martin C; van Luyn, Marja J A; Werker, Paul M N

    The purpose of this article is to give a concise review of the current state of the art in tissue engineering (TE) of skeletal muscle and the opportunities and challenges for future clinical applicability. The endogenous progenitor cells of skeletal muscle, i.e. satellite cells, show a high

  2. Alternative Aviation Fuels: Overview of Challenges, Opportunities, and Next Steps

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2017-03-28

    The Alternative Aviation Fuels: Overview of Challenges, Opportunities, and Next Steps report, published by the U.S. Department of Energy’s Bioenergy Technologies Office (BETO) provides an overview of the current state of alternative aviation fuels, based upon findings from recent peer-reviewed studies, scientific working groups, and BETO stakeholder input provided during the Alternative Aviation Fuel Workshop.

  3. South Africa in the BRICS: Opportunities, Challenges and Prospects1

    African Journals Online (AJOL)

    This study investigates the participation of South Africa in the BRICS group from an analytical perspective. It is argued that South Africa's membership to this group entails both opportunities and challenges for South Africa, the continent and the system of global governance. We seek to flesh out the potential mediumand ...

  4. Race, Ethnicity, and the Bible: Pedagogical Challenges and Curricular Opportunities

    Science.gov (United States)

    Byron, Gay L.

    2012-01-01

    Theological educators are now fostering dialogues, projects, and practices that are designed to acknowledge the challenges and opportunities resulting from the shifting racial and ethnic demographic climate in the U.S. and Canada. As well-intentioned as these efforts are, most of the scholarship focuses on the contemporary experiences of…

  5. the youth and the modern: challenges and opportunities

    African Journals Online (AJOL)

    Every generation has challenges that are specific to the youth and which look modern at the particular time and open up numerous opportunities. In each generation, some people are identified as “leaders” in one of two ways. First, there are those who stand out as “leaders” because they have natural attractions and emit ...

  6. Community in Online Higher Education: Challenges and Opportunities

    Science.gov (United States)

    Arasaratnam-Smith, Lily A.; Northcote, Maria

    2017-01-01

    Exploring the challenges and opportunities associated with the concepts of community and communication in online higher education, this paper reconsiders the intention to replicate face-to-face learning and teaching strategies in online learning environments. Rather than beginning with the assumption that face-to-face education is the prototype…

  7. Facebook: Challenges and Opportunities for Business Communication Students

    Science.gov (United States)

    Decarie, Christina

    2010-01-01

    In this article, the author describes her experience with networking on Facebook and discusses some important challenges and opportunities for business communication students. Facebook requires and enhances strong writing and interpersonal communication skills and it requires something new--a kind of literacy that students and teachers alike are…

  8. Scholarship of Teaching International Business: Challenges and Opportunities

    Science.gov (United States)

    Aggarwal, Raj; Goodell, John W.

    2011-01-01

    International business (IB) is an important topic for business schools as business is global, but much business school teaching of IB still seems inadequate. IB education can be challenging but also presents many opportunities. We need to build our knowledge base of effective IB teaching methods and procedures. Such knowledge can not only be used…

  9. Small reactors in the Canadian context: opportunities and challenges

    Energy Technology Data Exchange (ETDEWEB)

    Walker, R.S. [Atomic Energy of Canada Limited, Chalk River, Ontario (Canada)

    2013-07-01

    This presentation discusses the opportunities and challenges for small reactors in Canada. It concludes by suggesting that the success of small reactors in Canada will depend on a number of factors including private sector investment, access to international markets, stable, equitable and adaptable regulatory regime, public trust and technology.

  10. Linked Data: Opportunities and Challenges in Disability Research

    Science.gov (United States)

    Glasson, Emma J.; Hussain, Rafat

    2008-01-01

    Background: Disability research data often exist in the form of individual records located within discrete registers that may extend across sensitive political boundaries. Method: This paper discusses the opportunities and challenges associated with using linked health and administrative data for disability research, with examples from research…

  11. Teaching Culture: The Challenges and Opportunities of International Public Relations.

    Science.gov (United States)

    George, Amiso M.

    2003-01-01

    Focuses on the challenges and opportunities for international public relations practice. Looks at current United States-Arab relations issues in international crisis communication. Discusses those issues, especially the role of culture and media. Proposes strategies including a case study that teachers can use to help students become effective…

  12. The Global Outlook for Small Reactors: Opportunities, Challenges and Implementation

    International Nuclear Information System (INIS)

    Hughes, A.

    2012-01-01

    The fascinating topic of small nuclear is becoming more prevalent on the nuclear agenda. The discussions are generally focused within the country of technical origin. In this presentation 'The global outlook for small reactors' Rolls-Royce along with energy business analysts Douglas-Westwood present their shared views on the global opportunities for Small Reactor deployment in the context of the wider energy market. The presentation will: provide a compressive overview of trends and dynamics relating to Small Reactors in the context of the current world energy market, identify specific Small Reactor opportunities and areas of interest, address the challenges and potential solutions for Small Reactor deployment and operation.(author).

  13. The Role of Trees on Farms: Challenges and Opportunities

    International Nuclear Information System (INIS)

    Nyamai, D.O

    2007-01-01

    The challenges facing Kenyan forestry are deforestation and degradation due to increased demand for wood and additional agricultural land, inadequate resources to strengthen capacities in specific research areas including resource accounting, modelling the beneficial effects of carbon sequestration, policy analysis and products development for market dominance, great variations in institutional development and capacity for trees on farm and agroforestry research and development and inadequate research resources to mention but a few. The opportunities for improved forestry research include, economic growth, social welfare, promoting technologies and innovations for value-added processing agroforestry products for local and external effects, emerging private sector and existing regional market such as Common Market for Eastern and Southern Africa and the East African Community for opportunities for trade in agroforestry products and formulation of policies in favour of privatisation of services and management particularly the privatisation of industrial forest plantations that would offer opportunities for the development of smallholder tree crop enterprise

  14. Urban underground logistics system in China: Opportunities or challenges?

    Directory of Open Access Journals (Sweden)

    Zhilong Chen

    2017-09-01

    Full Text Available An urban underground logistics system (ULS is one important means of solving urban traffic problems that has unique advantages. Freight transportation in China requires a new transportation mode. Therefore, ULS has garnered increasing attention. However, to date, few scholars and practitioners have investigated ULS in China. Although ULS shows good development opportunities, it also faces great challenges. Based on the Macro-environment and situation analysis (PEST-SWOT model, which is a strategic analysis method that combines both SWOT and PEST to effectively identify advantages, disadvantages, opportunities and threats, this paper first uses PEST to analyze the macro-environment of ULS in China and identify its internal factors (i.e., advantages and disadvantages and external factors (i.e., opportunities and threats. Next, based on the SWOT framework, this paper proposes several development strategies and recommendations that provide a comprehensive and novel perspective to the study of ULS in China.

  15. Challenges and opportunities for Korean missionaries in Southern Africa

    Directory of Open Access Journals (Sweden)

    Kyung H. Oh

    2009-05-01

    Full Text Available This article describes the history of missions in Korea as well as the challenges and opportunities for Korean missionaries in Southern Africa. The most significant problems encountered by Korean missionaries include understanding local context, language and culture acquisition, and meeting the expectations of local people and local churches as well as those of sending churches in Korea. On a personal level, missionaries have to cope with family concerns, maintaining their spiritual life, health problems, financial concerns, frustrations and unfulfilled ideals. Korean missionaries in Southern Africa do, however, have a unique opportunity to serve the Church in its mission and, above all, to serve the Lord of the Church in his mission, although there are indeed difficulties to overcome and challenges to face.

  16. Processing Challenges and Opportunities of Camel Dairy Products

    DEFF Research Database (Denmark)

    Berhe, Tesfemariam; Seifu, Eyassu; Ipsen, Richard

    2017-01-01

    A review on the challenges and opportunities of processing camel milk into dairy products is provided with an objective of exploring the challenges of processing and assessing the opportunities for developing functional products from camel milk. The gross composition of camel milk is similar...... to bovine milk. Nonetheless, the relative composition, distribution, and the molecular structure of the milk components are reported to be different. Consequently, manufacturing of camel dairy products such as cheese, yoghurt, or butter using the same technology as for dairy products from bovine milk can...... result in processing difficulties and products of inferior quality. However, scientific evidence points to the possibility of transforming camel milk into products by optimization of the processing parameters. Additionally, camel milk has traditionally been used for its medicinal values and recent...

  17. The Opportunity and Challenge of The Age of Big Data

    Science.gov (United States)

    Yunguo, Hong

    2017-11-01

    The arrival of large data age has gradually expanded the scale of information industry in China, which has created favorable conditions for the expansion of information technology and computer network. Based on big data the computer system service function is becoming more and more perfect, and the efficiency of data processing in the system is improving, which provides important guarantee for the implementation of production plan in various industries. At the same time, the rapid development of fields such as Internet of things, social tools, cloud computing and the widen of information channel, these make the amount of data is increase, expand the influence range of the age of big data, we need to take the opportunities and challenges of the age of big data correctly, use data information resources effectively. Based on this, this paper will study the opportunities and challenges of the era of large data.

  18. Cultural Foundations of Female Entrepreneurship in Mexico: Challenges and Opportunities

    Directory of Open Access Journals (Sweden)

    Cavada Martha Cantú

    2018-03-01

    Full Text Available This paper analyses possible challenges and opportunities that Mexican female entrepreneurs face during the establishment of new enterprises. Based on in-depth interviews with female entrepreneurs and entrepreneurship experts, authors researched opportunities in the form of governmental and non-governmental institutional support, growing entrepreneurship, social awareness and women empowerment. However, lack of credibility, fear of vulnerability to criticism and social pressure are some challenges associated with gender egalitarianism. In such, the authors proved that Mexican culture impacts women in some ways more than the others. Institutional collectivism was the cultural dimension with higher positive impact on women, followed by gender egalitarianism with a neutral to positive impact and the power distance with a neutral influence on women.

  19. [The opportunities, challenges and trends in the rejuvenation of microbiology].

    Science.gov (United States)

    Shen, Ping; Chen, Xiangdong

    2010-01-01

    In history, the development of microbiology had undergone two golden ages and some depression time as well. In the last two decades, the application of many physiochemical technologies including genomics, structural biology, bioinformatics, PCR, and high-resolution microscopy has led to a series of breakthroughs in microbiology. Microbiology has now awakened and entered its third golden age for development. This review discusses our view of the opportunities, challenges, and trends in the current advancement of microbiology. The topics include: (1) The two golden ages for microbiology in history. (2) The opportunities and challenges in the rejuvenation of microbiology. (3) The characteristics and trends of the current development of microbiology. (4) Integral microbiology--the hallmark of the third golden age.

  20. From mobile mental health to mobile wellbeing: opportunities and challenges.

    Science.gov (United States)

    Gaggioli, Andrea; Riva, Giuseppe

    2013-01-01

    The combination of smart phones, wearable sensor devices and social media offer new ways of monitoring and promoting mental and physical wellbeing. In this contribution, we describe recent developments in the field of mobile healthcare (or mHealth), by focusing in particular on mobile mental health applications. First, we examine the potential benefits associated with this approach, providing examples from existing projects. Next, we identify and explain possible differences in focus between mobile mental health and mobile wellbeing applications. Finally, we discuss some open challenges associated with the implementation of this vision, ranging from the lack of evidence-based validation to privacy, security and ethical concerns.

  1. National health inequality monitoring: current challenges and opportunities.

    Science.gov (United States)

    Hosseinpoor, Ahmad Reza; Bergen, Nicole; Schlotheuber, Anne; Boerma, Ties

    National health inequality monitoring needs considerably more investment to realize equity-oriented health improvements in countries, including advancement towards the Sustainable Development Goals. Following an overview of national health inequality monitoring and the associated resource requirements, we highlight challenges that countries may encounter when setting up, expanding or strengthening national health inequality monitoring systems, and discuss opportunities and key initiatives that aim to address these challenges. We provide specific proposals on what is needed to ensure that national health inequality monitoring systems are harnessed to guide the reduction of health inequalities.

  2. Pricing medicines: theory and practice, challenges and opportunities.

    Science.gov (United States)

    Gregson, Nigel; Sparrowhawk, Keiron; Mauskopf, Josephine; Paul, John

    2005-02-01

    The pricing of medicines has become one of the most hotly debated topics of recent times, with the pharmaceutical industry seemingly being attacked from all quarters. From a company perspective, determining the price for each new product is more crucial than ever, given the present dearth of new drug introductions. But how are pricing strategies developed in practice? What is value-based pricing and how are financial models of return on investment constructed? What are the challenges faced in setting the price for a particular product, and how will scientific and environmental trends provide future pricing challenges or opportunities?

  3. RNAi nanomedicines: challenges and opportunities within the immune system

    International Nuclear Information System (INIS)

    Weinstein, Shiri; Peer, Dan

    2010-01-01

    RNAi, as a novel therapeutic modality, has an enormous potential to bring the era of personalized medicine one step further from notion into reality. However, delivery of RNAi effector molecules into their target tissues and cells remain extremely challenging. Major attempts have been made in recent years to develop sophisticated nanocarriers that could overcome these hurdles. This review will present the recent progress with the challenges and opportunities in this emerging field, focusing mostly on the in vivo applications with special emphasis on the strategies for RNAi delivery into immune cells. (topical review)

  4. Opportunities and Challenges of Multiplex Assays: A Machine Learning Perspective.

    Science.gov (United States)

    Chen, Junfang; Schwarz, Emanuel

    2017-01-01

    Multiplex assays that allow the simultaneous measurement of multiple analytes in small sample quantities have developed into a widely used technology. Their implementation spans across multiple assay systems and can provide readouts of similar quality as the respective single-plex measures, albeit at far higher throughput. Multiplex assay systems are therefore an important element for biomarker discovery and development strategies but analysis of the derived data can face substantial challenges that may limit the possibility of identifying meaningful biological markers. This chapter gives an overview of opportunities and challenges of multiplexed biomarker analysis, in particular from the perspective of machine learning aimed at identification of predictive biological signatures.

  5. Publishing in multi-modal formats:opportunities and challenges

    OpenAIRE

    Knapton, Olivia

    2013-01-01

    Online dissemination of academic research presents a host of opportunities and challenges to those using audio and video data files. When working with spoken data the transcription process converts the data into a written format that is both easier to manage and easier to disseminate. Yet with the multimodal potential of online publication, transcripts may no longer need to be the default option for data presentation. This article reviews the decisions that researchers have to make when conve...

  6. Blockchains for Business Process Management - Challenges and Opportunities

    OpenAIRE

    Mendling, Jan; Weber, Ingo; van der Aalst, Wil; Brocke, Jan vom; Cabanillas, Cristina; Daniel, Florian; Debois, Soren; Di Ciccio, Claudio; Dumas, Marlon; Dustdar, Schahram; Gal, Avigdor; Garcia-Banuelos, Luciano; Governatori, Guido; Hull, Richard; La Rosa, Marcello

    2017-01-01

    Blockchain technology offers a sizable promise to rethink the way inter-organizational business processes are managed because of its potential to realize execution without a central party serving as a single point of trust (and failure). To stimulate research on this promise and the limits thereof, in this paper we outline the challenges and opportunities of blockchain for Business Process Management (BPM). We first reflect how blockchains could be used in the context of the established BPM l...

  7. Challenges and Opportunities of Grid Modernization and Electric Transportation

    Energy Technology Data Exchange (ETDEWEB)

    Graham, Robert L. [Dept. of Energy (DOE), Washington DC (United States); Francis, Julieta [Allegheny Science and Technology, Bridgeport, WV (United States); Bogacz, Richard J. [Allegheny Science and Technology, Bridgeport, WV (United States)

    2017-03-31

    Grid investments that support electric vehicle deployments as a part of planned modernization efforts can enable a more efficient and cost-effective transition to electric transportation and allow investor-owned electric companies and public power companies to realize new revenue resources in times of flat or declining loads. This paper discusses the challenges and opportunities associated with an increase in plug-in electric vehicle (PEV) adoption and how working together both sectors stand to benefit from closer integration.

  8. The opportunities and challenges for ICT in science education

    OpenAIRE

    Ferk Savec, Vesna

    2017-01-01

    This article examines the opportunities and challenges for the use of ICT in science education in the light of science teachers’ Technological Pedagogical Content Knowledge (TPACK). Some of the variables that have been studied with regard to the TPACK fra mework in science classrooms (such as teachers’ self - efficacy, gender, teaching experience, teachers’ beliefs, etc.) are reviewed, and variations of the TPACK framework specific for science education ...

  9. Mapping educational opportunities for healthcare workers on antimicrobial resistance and stewardship around the world.

    Science.gov (United States)

    Rogers Van Katwyk, Susan; Jones, Sara L; Hoffman, Steven J

    2018-02-05

    Antimicrobial resistance is an important global issue facing society. Healthcare workers need to be engaged in solving this problem, as advocates for rational antimicrobial use, stewards of sustainable effectiveness, and educators of their patients. To fulfill this role, healthcare workers need access to training and educational resources on antimicrobial resistance. To better understand the resources available to healthcare workers, we undertook a global environmental scan of educational programs and resources targeting healthcare workers on the topic of antimicrobial resistance and antimicrobial stewardship. Programs were identified through contact with key experts, web searching, and academic literature searching. We summarized programs in tabular form, including participating organizations, region, and intended audience. We developed a coding system to classify programs by program type and participating organization type, assigning multiple codes as necessary and creating summary charts for program types, organization types, and intended audience to illustrate the breadth of available resources. We identified 94 educational initiatives related to antimicrobial resistance and antimicrobial stewardship, which represent a diverse array of programs including courses, workshops, conferences, guidelines, public outreach materials, and online-resource websites. These resources were developed by a combination of government bodies, professional societies, universities, non-profit and community organizations, hospitals and healthcare centers, and insurance companies and industry. Most programs either targeted healthcare workers collectively or specifically targeted physicians. A smaller number of programs were aimed at other healthcare worker groups including pharmacists, nurses, midwives, and healthcare students. Our environmental scan shows that there are many organizations working to develop and share educational resources for healthcare workers on antimicrobial

  10. Qualitative research in rehabilitation science: opportunities, challenges, and future directions.

    Science.gov (United States)

    VanderKaay, Sandra; Moll, Sandra E; Gewurtz, Rebecca E; Jindal, Pranay; Loyola-Sanchez, Adalberto; Packham, Tara L; Lim, Chun Y

    2018-03-01

    Qualitative research has had a significant impact within rehabilitation science over time. During the past 20 years the number of qualitative studies published per year in Disability and Rehabilitation has markedly increased (from 1 to 54). In addition, during this period there have been significant changes in how qualitative research is conceptualized, conducted, and utilized to advance the field of rehabilitation. The purpose of this article is to reflect upon the progress of qualitative research within rehabilitation to date, to explicate current opportunities and challenges, and to suggest future directions to continue to strengthen the contribution of qualitative research in this field. Relevant literature searches were conducted in electronic data bases and reference lists. Pertinent literature was examined to identify current opportunities and challenges for qualitative research use in rehabilitation and to identify future directions. Six key areas of opportunity and challenge were identified: (a) paradigm shifts, (b) advancements in methodology, (c) emerging technology, (d) advances in quality evaluation, (e) increasing popularity of mixed methods approaches, and (f) evolving approaches to knowledge translation. Two important future directions for rehabilitation are posited: (1) advanced training in qualitative methods and (2) engaging qualitative communities of research. Qualitative research is well established in rehabilitation and has an important place in the continued growth of this field. Ongoing development of qualitative researchers and methods are essential. Implications for Rehabilitation Qualitative research has the potential to improve rehabilitation practice by addressing some of the most pervasive concerns in the field such as practitioner-client interaction, the subjective and lived experience of disability, and clinical reasoning and decision making. This will serve to better inform those providing rehabilitation services thereby benefiting

  11. Financing dengue vaccine introduction in the Americas: challenges and opportunities.

    Science.gov (United States)

    Constenla, Dagna; Clark, Samantha

    2016-01-01

    Dengue has escalated in the region of the Americas unabated despite major investments in integrated vector control and prevention strategies. An effective and affordable dengue vaccine can play a critical role in reducing the human and economic costs of the disease by preventing millions around the world from getting sick. However, there are considerable challenges on the path towards vaccine introduction. These include lack of sufficient financing tools, absence of capacity within national level decision-making bodies, and demands that new vaccines place on stressed health systems. Various financing models can be used to overcome these challenges including setting up procurement mechanisms, integrating regional and domestic taxes, and setting up low interest multilateral loans. In this paper we review these challenges and opportunities of financing dengue vaccine introduction in the Americas.

  12. Social media in the healthcare context: Ethical challenges and recommendations

    Directory of Open Access Journals (Sweden)

    Christoffel Grobler

    2016-05-01

    Full Text Available The popularity of social media has grown rapidly and healthcare practitioners and students commonly use sites such as Facebook. The ethical and professional implications and their benefits and hazards must be considered. Concerns include blurring of boundaries between an individual’s public and professional lives, maintaining privacy and confidentiality of patient information, damaging the public image of the profession and inter-professional relationships. The same laws that apply to conduct in the real world also apply in cyberspace. Harmful or derogatory posts may result in a defamation lawsuit. The internet may also provide opportunities for patient education through peerreviewed websites and to build professional networks. Institutions should have policies on the uses of social media. Emerging technology will continue to change the landscape of social media and social networking and the way patients and practitioners use websites will continue to evolve. Practitioners should proactively manage digital identity by reviewing publicly available material and maintaining strict privacy settings about their information.

  13. PSYCHOLOGY 2.0: OPPORTUNITIES AND CHALLENGES FOR THE PSYCHOLOGY PROFESSIONAL IN THE FIELD OF EHEALTH

    Directory of Open Access Journals (Sweden)

    Manuel Armayones

    2015-05-01

    Full Text Available eHealth is recognised as a strategic priority for the healthcare system at the national, European and international levels. Psychology, as a health profession, has the opportunity and the obligation to extend its activity into an area in which it has not had a notable presence until now. The basic principles of the Web 2.0 integrated into professional practice require, more than simply the use of technology, a new attitude and commitment towards collaboration, the adoption of a transversal perspective of technology in all areas of activity of psychologists and the consideration of people’s self-management abilities regarding their own health. Psychology 2.0 proposes interesting job opportunities and challenges, to which the discipline and the professional associations must respond, in order to guarantee service quality to the people.

  14. Opportunities and ethical challenges for the practice of medicine in the digital era.

    Science.gov (United States)

    Herron, Patrick D

    2015-06-01

    Technological advances have been a driving force in the practice of medicine. From the discovery of x-rays' medical applications to the utilization of dialysis and surgical transplantation of organs, technology has presented new opportunities, and at times, ethical challenges for physicians. In recent years, the increased proliferation of social media tools has had a significant impact on how people engage with one another, and how they want to engage with their healthcare providers. Medical schools have begun to examine some of the issues surrounding use of social media in the context of professionalism in their curricula. Many of the physicians already in practice are left to grapple with how to learn about and wield social media in not only a professional capacity and their personal lives, but often where the two intersect. This paper will explore both opportunities for social media engagement and ethical concerns such usage presents to physicians and in particular to those in the field of musculoskeletal medicine.

  15. Iterative near-term ecological forecasting: Needs, opportunities, and challenges.

    Science.gov (United States)

    Dietze, Michael C; Fox, Andrew; Beck-Johnson, Lindsay M; Betancourt, Julio L; Hooten, Mevin B; Jarnevich, Catherine S; Keitt, Timothy H; Kenney, Melissa A; Laney, Christine M; Larsen, Laurel G; Loescher, Henry W; Lunch, Claire K; Pijanowski, Bryan C; Randerson, James T; Read, Emily K; Tredennick, Andrew T; Vargas, Rodrigo; Weathers, Kathleen C; White, Ethan P

    2018-02-13

    Two foundational questions about sustainability are "How are ecosystems and the services they provide going to change in the future?" and "How do human decisions affect these trajectories?" Answering these questions requires an ability to forecast ecological processes. Unfortunately, most ecological forecasts focus on centennial-scale climate responses, therefore neither meeting the needs of near-term (daily to decadal) environmental decision-making nor allowing comparison of specific, quantitative predictions to new observational data, one of the strongest tests of scientific theory. Near-term forecasts provide the opportunity to iteratively cycle between performing analyses and updating predictions in light of new evidence. This iterative process of gaining feedback, building experience, and correcting models and methods is critical for improving forecasts. Iterative, near-term forecasting will accelerate ecological research, make it more relevant to society, and inform sustainable decision-making under high uncertainty and adaptive management. Here, we identify the immediate scientific and societal needs, opportunities, and challenges for iterative near-term ecological forecasting. Over the past decade, data volume, variety, and accessibility have greatly increased, but challenges remain in interoperability, latency, and uncertainty quantification. Similarly, ecologists have made considerable advances in applying computational, informatic, and statistical methods, but opportunities exist for improving forecast-specific theory, methods, and cyberinfrastructure. Effective forecasting will also require changes in scientific training, culture, and institutions. The need to start forecasting is now; the time for making ecology more predictive is here, and learning by doing is the fastest route to drive the science forward.

  16. Challenges and opportunities associated with waste management in India

    Science.gov (United States)

    Kumar, Sunil; Smith, Stephen R.; Fowler, Geoff; Velis, Costas; Kumar, S. Jyoti; Arya, Shashi; Rena; Kumar, Rakesh

    2017-01-01

    India faces major environmental challenges associated with waste generation and inadequate waste collection, transport, treatment and disposal. Current systems in India cannot cope with the volumes of waste generated by an increasing urban population, and this impacts on the environment and public health. The challenges and barriers are significant, but so are the opportunities. This paper reports on an international seminar on ‘Sustainable solid waste management for cities: opportunities in South Asian Association for Regional Cooperation (SAARC) countries’ organized by the Council of Scientific and Industrial Research-National Environmental Engineering Research Institute and the Royal Society. A priority is to move from reliance on waste dumps that offer no environmental protection, to waste management systems that retain useful resources within the economy. Waste segregation at source and use of specialized waste processing facilities to separate recyclable materials has a key role. Disposal of residual waste after extraction of material resources needs engineered landfill sites and/or investment in waste-to-energy facilities. The potential for energy generation from landfill via methane extraction or thermal treatment is a major opportunity, but a key barrier is the shortage of qualified engineers and environmental professionals with the experience to deliver improved waste management systems in India. PMID:28405362

  17. Challenges and opportunities associated with waste management in India.

    Science.gov (United States)

    Kumar, Sunil; Smith, Stephen R; Fowler, Geoff; Velis, Costas; Kumar, S Jyoti; Arya, Shashi; Rena; Kumar, Rakesh; Cheeseman, Christopher

    2017-03-01

    India faces major environmental challenges associated with waste generation and inadequate waste collection, transport, treatment and disposal. Current systems in India cannot cope with the volumes of waste generated by an increasing urban population, and this impacts on the environment and public health. The challenges and barriers are significant, but so are the opportunities. This paper reports on an international seminar on 'Sustainable solid waste management for cities: opportunities in South Asian Association for Regional Cooperation (SAARC) countries' organized by the Council of Scientific and Industrial Research-National Environmental Engineering Research Institute and the Royal Society. A priority is to move from reliance on waste dumps that offer no environmental protection, to waste management systems that retain useful resources within the economy. Waste segregation at source and use of specialized waste processing facilities to separate recyclable materials has a key role. Disposal of residual waste after extraction of material resources needs engineered landfill sites and/or investment in waste-to-energy facilities. The potential for energy generation from landfill via methane extraction or thermal treatment is a major opportunity, but a key barrier is the shortage of qualified engineers and environmental professionals with the experience to deliver improved waste management systems in India.

  18. Using time-driven activity-based costing to identify value improvement opportunities in healthcare.

    Science.gov (United States)

    Kaplan, Robert S; Witkowski, Mary; Abbott, Megan; Guzman, Alexis Barboza; Higgins, Laurence D; Meara, John G; Padden, Erin; Shah, Apurva S; Waters, Peter; Weidemeier, Marco; Wertheimer, Sam; Feeley, Thomas W

    2014-01-01

    As healthcare providers cope with pricing pressures and increased accountability for performance, they should be rededicating themselves to improving the value they deliver to their patients: better outcomes and lower costs. Time-driven activity-based costing offers the potential for clinicians to redesign their care processes toward that end. This costing approach, however, is new to healthcare and has not yet been systematically implemented and evaluated. This article describes early time-driven activity-based costing work at several leading healthcare organizations in the United States and Europe. It identifies the opportunities they found to improve value for patients and demonstrates how this costing method can serve as the foundation for new bundled payment reimbursement approaches.

  19. Nanomedicine in cancer therapy: challenges, opportunities, and clinical applications.

    Science.gov (United States)

    Wicki, Andreas; Witzigmann, Dominik; Balasubramanian, Vimalkumar; Huwyler, Jörg

    2015-02-28

    Cancer is a leading cause of death worldwide. Currently available therapies are inadequate and spur demand for improved technologies. Rapid growth in nanotechnology towards the development of nanomedicine products holds great promise to improve therapeutic strategies against cancer. Nanomedicine products represent an opportunity to achieve sophisticated targeting strategies and multi-functionality. They can improve the pharmacokinetic and pharmacodynamic profiles of conventional therapeutics and may thus optimize the efficacy of existing anti-cancer compounds. In this review, we discuss state-of-the-art nanoparticles and targeted systems that have been investigated in clinical studies. We emphasize the challenges faced in using nanomedicine products and translating them from a preclinical level to the clinical setting. Additionally, we cover aspects of nanocarrier engineering that may open up new opportunities for nanomedicine products in the clinic. Copyright © 2014 Elsevier B.V. All rights reserved.

  20. Urbanization in Africa: challenges and opportunities for conservation

    Science.gov (United States)

    Güneralp, Burak; Lwasa, Shuaib; Masundire, Hillary; Parnell, Susan; Seto, Karen C.

    2017-12-01

    Africa, a continent exceptionally rich in biodiversity, is rapidly urbanizing. Africa’s urbanization is manifest in the growth of its megacities as well as that of its smaller towns and cities. The conservation planning and practice will increasingly need to account for direct and indirect impacts of the continent’s urbanization. The objective of our study is to pinpoint the outstanding challenges and opportunities afforded by the growing cities on the continent to the conservation goals and practices. While there have been many studies on the impacts of urbanization and development on conservation in Africa these studies tended to focus on specific issues. Here, we provide a synthesis of this body of work supported by new analysis. Urban areas, growing both in population and in land cover, pose threats to the integrity of the continent’s ecosystems and biodiversity but their growth also create opportunities for conservation. The burgeoning urban populations, especially in Sub-Saharan Africa, increase the strain on already insufficient infrastructure and bring new governance challenges. Yet, Africa’s ecosystems can serve as foundations for green infrastructure to serve the needs of its urban populations while safeguarding fragile biodiversity. Overall, while worsening social problems overshadow the concerns for biodiversity there are also promising initiatives to bring these concerns into the fold to address social, institutional, and ecological challenges that emerge with the continued urbanization of the continent.

  1. Opportunities and challenges in developing gas markets in South America

    Energy Technology Data Exchange (ETDEWEB)

    Duarte, Cristiano Boaventura [PETROBRAS S.A., Rio de Janeiro, RJ (Brazil)

    2008-07-01

    The article has the objective of identifying and analyzing the key market levers and drivers, emerging issues and challenges in developing the gas markets in South America. In section 1, the paper provides an overview of the most relevant indicators in the natural gas markets of the region. Data such as natural gas proven reserves; production; consumption; trade movements (by pipeline and LNG) and main aspects of regulatory framework are shown. In section 2, some of the key challenges and opportunities in developing gas markets in the region are identified, including those relating to market integration, political aspects and the main players' investments. In section 3, possible strategies from governments and enterprises to overcome those challenges, and seize the potential opportunities of the region are examined. In section 4, the conclusions point to the potential of developing the gas markets as a means to diversify the energy sources in the region, fostering a successful process of economic growth and political integration in the area. (author)

  2. Nanomaterials and future aerospace technologies: opportunities and challenges

    Science.gov (United States)

    Vaia, Richard A.

    2012-06-01

    Two decades of extensive investment in nanomaterials, nanofabrication and nanometrology have provided the global engineering community a vast array of new technologies. These technologies not only promise radical change to traditional industries, such as transportation, information and aerospace, but may create whole new industries, such as personalized medicine and personalized energy harvesting and storage. The challenge today for the defense aerospace community is determining how to accelerate the conversion of these technical opportunities into concrete benefits with quantifiable impact, in conjunction with identifying the most important outstanding scientific questions that are limiting their utilization. For example, nanomaterial fabrication delivers substantial tailorablity beyond a traditional material data sheet. How can we integrate this tailorability into agile manufacturing and design methods to further optimize the performance, cost and durability of future resilient aerospace systems? The intersection of nano-based metamaterials and nanostructured devices with biotechnology epitomizes the technological promise of autonomous systems and enhanced human-machine interfaces. What then are the key materials and processes challenges that are inhibiting current lab-scale innovation from being integrated into functioning systems to increase effectiveness and productivity of our human resources? Where innovation is global, accelerating the use of breakthroughs, both for commercial and defense, is essential. Exploitation of these opportunities and finding solutions to the associated challenges for defense aerospace will rely on highly effective partnerships between commercial development, scientific innovation, systems engineering, design and manufacturing.

  3. Rainwater harvesting in South Africa: Challenges and opportunities

    Science.gov (United States)

    Mwenge Kahinda, J.; Taigbenu, A. E.

    Water paucity remains a major threat to poverty, hunger alleviation as well as sustainable development. Innovative water technologies such as rainwater harvesting (RWH) have the potential to improve rural water supply and contribute to the provision of the first 6 kl of water consumed monthly. RWH can also be the solution to South Africa food security by increasing water productivity of dryland agriculture and enabling homestead gardening. Although used for decades in South Africa, rainwater harvesting (RWH) is still far from being utilised to its full potential as unresolved challenges prevent its wide scale adoption. The paper presents the challenges and opportunities to the upscaling of RWH in South Africa. Key challenges preventing the nationwide expansion of RWH are the current water related legislations, the lack of finances and the absence of a national umbrella body that coordinates. While opportunities lie in the worth of knowledge gathered by research projects, funded over the last two decades, on the biophysical and socio-economic impacts of RWH.

  4. Towards a More Responsive Judge: Challenges and Opportunities

    Directory of Open Access Journals (Sweden)

    Machteld W. de Hoon

    2014-11-01

    Full Text Available This paper explores the changes that have taken place in the attitude of judges towards their role and tasks as well as actual judicial practices. The result of this exploration is a reflection upon the challenges and opportunities for a new, more responsive judge. The main characteristic of this new judge is that he or she looks beyond the purely legal coordinates of the dispute, in order to discuss which method of dispute resolution (a settlement, a referral to mediation or a court decision is most likely to result in a viable and sustainable solution. These changes in attitude are part of broader developments that have taken place in actual judicial practices. The context in which these changes have occurred helps us to gain a better understanding of the changes, the barriers to change and the opportunities to overcome these challenges. The leading assumption in this research is that during the past ten years there has been an extensive change in the way judges think about their role in dispute resolution and at the same time many judges experience difficulties in applying their new-found understanding to their work in the courts. Our data have been gathered through court observations, interviews and expert meetings. In addition, our analyses are based on relevant literature in the field of judicial dispute resolution (JDR as well as insights from our own previous research projects. We primarily focus on civil and administrative disputes in the Netherlands. Occasionally, we also point to trends and challenges elsewhere.

  5. Levinas's ethics as a basis of healthcare - challenges and dilemmas.

    Science.gov (United States)

    Nordtug, Birgit

    2015-01-01

    Levinas's ethics has in the last decades exerted a significant influence on Nursing and Caring Science. The core of Levinas's ethics - his analyses of how our subjectivity is established in the ethical encounter with our neighbour or the Other - is applied both to healthcare practice and in the project of building an identity of Nursing and Caring Science. Levinas's analyses are highly abstract and metaphysical, and also non-normative. Thus, his analyses cannot be applied directly to practical problems and questions. Theorists in Nursing and Caring Science are generally aware of this. Nevertheless, many of them use Levinas's analyses to explore and solve questions of practical and normative character. This article focuses on the challenges and dilemmas of using Levinas in this manner. The article is divided into two parts. The first part presents some central ideas of Levinas's ethics based on the latter part of his authorship. The main focus is on the radicalism of Levinas's critique of the symbolic order (which includes concepts, categories, knowledge, etc.) - or as he puts it 'the said' - as a basis for subjectivity and responsibility. Levinas's notions of saying, anarchy, and singularity accentuate this point of view. These notions refer to conditions in the language, which counteract the symbolic order in the ethical encounter to such an extent that it becomes an incomprehensible. Levinas gives the argumentation a metaphysical frame: The encounter with the incomprehensible is an encounter with the Holy, which is not the ontological God, but a metaphysical desire. It is a mystery as to what this means, and herein lies possibly the main challenge when using Levinas's ethics in science and research: How to maintain the radicalism of his critique of the symbolic order when this is to be communicated in a scientific context that expects clarification of statements and ideas? The second part of the article explores this question by examining how some theorists use

  6. Vibration problems in nuclear power plants - challenges and opportunities

    International Nuclear Information System (INIS)

    Kakodkar, A.; Moorthy, R.I.K.

    1993-01-01

    Through specific examples like the Dhruva fuel vibration problems, it is shown that in different stages of a plant construction and operation that the vibration problems provide many challenging opportunities for innovative solutions to be applied. These examples also show that in-depth understanding of the dynamics of structures and equipment and general engineering skill could be used profitably to solve the different vibration problems and also to use the vibration signals effectively to monitor the health of the equipment and structures. Considering the safety and economic implications it can be concluded that the scope for application of these techniques is rather limitless. (author). 7 refs., 10 figs

  7. Introducing sustainable development: challenges and opportunities for the energy sector

    International Nuclear Information System (INIS)

    Anon.

    2004-01-01

    The World Energy Council held its 19. world congress in Sydney (Australia) from September 5 to 9 2004, focusing on the theme 'Delivering sustainability: challenges and opportunities for the energy industry'. More than 2500 participants from all around the world attended the presentations, round table sessions, seminars and exhibitions. In this article, we will be featuring the conclusions from the congress. The next conference will be held from November 11 to 15 2007 in Rome (Italy) on the theme of 'The security and quality of energy supplies'. (authors)

  8. Improvement of Salinity Stress Tolerance in Rice: Challenges and Opportunities

    Directory of Open Access Journals (Sweden)

    Thi My Linh Hoang

    2016-10-01

    Full Text Available Rice (Oryza sativa L. is an important staple crop that feeds more than one half of the world’s population and is the model system for monocotyledonous plants. However, rice is very sensitive to salinity and is the most salt sensitive cereal crop with a threshold of 3 dSm−1 for most cultivated varieties. Despite many attempts using different strategies to improve salinity tolerance in rice, the achievements so far are quite modest. This review aims to discuss challenges that hinder the improvement of salinity stress tolerance in rice as well as potential opportunities for enhancing salinity stress tolerance in this important crop.

  9. BIG DATA IN TAMIL: OPPORTUNITIES, BENEFITS AND CHALLENGES

    OpenAIRE

    R.S. Vignesh Raj; Babak Khazaei; Ashik Ali

    2015-01-01

    This paper gives an overall introduction on big data and has tried to introduce Big Data in Tamil. It discusses the potential opportunities, benefits and likely challenges from a very Tamil and Tamil Nadu perspective. The paper has also made original contribution by proposing the ‘big data’s’ terminology in Tamil. The paper further suggests a few areas to explore using big data Tamil on the lines of the Tamil Nadu Government ‘vision 2023’. Whilst, big data has something to offer everyone, it ...

  10. Workplace diversity and public policy: challenges and opportunities for psychology.

    Science.gov (United States)

    Fassinger, Ruth E

    2008-01-01

    This article outlines both challenges and opportunities for psychology of issues related to diversity in education and work. For the purposes of this discussion, "diverse" populations include four groups currently marginalized and disadvantaged in the U.S. workplace: women, people of color, sexual minorities, and people with disabilities. An overview of employment participation patterns for these groups is presented, workplace barriers arising from marginalized status are highlighted, and the article concludes with a discussion of work-related legislative and public policy fronts that can be informed and influenced by the contributions of psychologists. Copyright (c) 2008 APA, all rights reserved.

  11. Enterprise Implementation of Digital Pathology: Feasibility, Challenges, and Opportunities.

    Science.gov (United States)

    Hartman, D J; Pantanowitz, L; McHugh, J S; Piccoli, A L; OLeary, M J; Lauro, G R

    2017-10-01

    Digital pathology is becoming technically possible to implement for routine pathology work. At our institution, we have been using digital pathology for second opinion intraoperative consultations for over 10 years. Herein, we describe our experience in converting to a digital pathology platform for primary pathology diagnosis. We implemented an incremental rollout for digital pathology on subspecialty benches, beginning with cases that contained small amounts of tissue (biopsy specimens). We successfully scanned over 40,000 slides through our digital pathology system. Several lessons (both challenges and opportunities) were learned through this implementation. A successful conversion to digital pathology requires pre-imaging adjustments, integrated software and post-imaging evaluations.

  12. Challenges and opportunities in mapping land use intensity globally

    DEFF Research Database (Denmark)

    Kuemmerle, Tobias; Erb, Karlheinz; Meyfroidt, Patrick

    2013-01-01

    Future increases in land-based production will need to focus more on sustainably intensifying existing production systems. Unfortunately, our understanding of the global patterns of land use intensity is weak, partly because land use intensity is a complex, multidimensional term, and partly becau...... challenges and opportunities for mapping land use intensity for cropland, grazing, and forestry systems, and identify key issues for future research....... we lack appropriate datasets to assess land use intensity across broad geographic extents. Here, we review the state of the art regarding approaches for mapping land use intensity and provide a comprehensive overview of available global-scale datasets on land use intensity. We also outline major...

  13. Technology transfer from accelerator laboratories (challenges and opportunities)

    International Nuclear Information System (INIS)

    Verma, V.K.; Gardner, P.L.

    1994-06-01

    It is becoming increasingly evident that technology transfer from research laboratories must be a key element of their comprehensive strategic plans. Technology transfer involves using a verified and organized knowledge and research to develop commercially viable products. Management of technology transfer is the art of organizing and motivating a team of scientists, engineers and manufacturers and dealing intelligently with uncertainties. Concurrent engineering is one of the most effective approaches to optimize the process of technology transfer. The challenges, importance, opportunities and techniques of transferring technology from accelerator laboratories are discussed. (author)

  14. Blockchains for Business Process Management - Challenges and Opportunities

    DEFF Research Database (Denmark)

    Mendling, Jan; Weber, Ingo; Van Der Aalst, Wil

    2018-01-01

    Blockchain technology offers a sizable promise to rethink the way inter-organizational business processes are managed because of its potential to realize execution without a central party serving as a single point of trust (and failure). To stimulate research on this promise and the limits thereof......, in this paper we outline the challenges and opportunities of blockchain for Business Process Management (BPM). We first reflect how blockchains could be used in the context of the established BPM lifecycle and second how they might become relevant beyond. We conclude our discourse with a summary of seven...... research directions for investigating the application of blockchain technology in the context of BPM...

  15. Regional power marketing opportunities : current challenges and future outlooks

    International Nuclear Information System (INIS)

    Stiers, M.

    1998-01-01

    The North American demand for electric power and natural gas by sector was described and a comparison was made between the number of FERC certified electric power marketers versus natural gas marketing companies between 1986 and 1997 to illustrate the extent of changes that occurred during the decade. Regional opportunities for energy marketers were reviewed. By way of current challenges, the author identified (1) regulatory impediments, (2) divestiture of assets, (3) creation of an effective ISO, (4) establishment of effective pricing mechanisms, (5) customer systems and infrastructure, (6) forcing legislative reform, and (7) stranded cost recovery, as the most important. figs

  16. Journalism in virtual reality : opportunities and future research challenges

    OpenAIRE

    Sirkkunen, Esa; Väätäjä, Heli; Uskali, Turo; Rezaei, Parisa Pour

    2016-01-01

    This paper presents a state-of-the-art overview on journalism and its opportunities and challenges in virtual reality. First we take a look at what kind of real-life journalistic experiments there have been made in this field so far, then we analyze the research literature on journalistic VR. The paper proceeds to discuss the emergence of virtual reality and immersive journalism explored in the latest reports in the fields of HCI and VR design. In order to analyse VR-journalism...

  17. Family caregiver recruitment via social media: challenges, opportunities and lessons.

    Science.gov (United States)

    Hansen, Dana; Sheehan, Denice K; Stephenson, Pam

    2017-02-02

    Illness blogs are a way seriously ill people communicate publicly about their illness journey. As communication about serious illness increases on social media, it is important to evaluate how this affects the family caregiver. However, identifying and accessing family caregivers remains challenging, especially via social media. The aim of this article is to report the opportunities, challenges and lessons learned from using social media to recruit family caregivers. Recruitment methods included posting study invitations on illness blogs, advertising through Facebook and placing study fliers in the community. Using social media to recruit was inexpensive and provided a wide geographical reach. One important finding was discovering the importance of using language in the recruitment materials that family caregivers could identify with to help deem themselves as eligible to participate in the study.

  18. Accelerator Challenges and Opportunities for Future Neutrino Experiments

    International Nuclear Information System (INIS)

    Zisman, Michael S.

    2010-01-01

    There are three types of future neutrino facilities currently under study, one based on decays of stored beta-unstable ion beams (Beta Beams), one based on decays of stored muon beams (Neutrino Factory), and one based on the decays of an intense pion beam (Superbeam). In this paper we discuss the challenges each design team must face and the R and D being carried out to turn those challenges into technical opportunities. A new program, the Muon Accelerator Program, has begun in the U.S. to carry out the R D for muon-based facilities, including both the Neutrino Factory and, as its ultimate goal, a Muon Collider. The goals of this program will be briefly described.

  19. Big Data and Biomedical Informatics: A Challenging Opportunity

    Science.gov (United States)

    2014-01-01

    Summary Big data are receiving an increasing attention in biomedicine and healthcare. It is therefore important to understand the reason why big data are assuming a crucial role for the biomedical informatics community. The capability of handling big data is becoming an enabler to carry out unprecedented research studies and to implement new models of healthcare delivery. Therefore, it is first necessary to deeply understand the four elements that constitute big data, namely Volume, Variety, Velocity, and Veracity, and their meaning in practice. Then, it is mandatory to understand where big data are present, and where they can be beneficially collected. There are research fields, such as translational bioinformatics, which need to rely on big data technologies to withstand the shock wave of data that is generated every day. Other areas, ranging from epidemiology to clinical care, can benefit from the exploitation of the large amounts of data that are nowadays available, from personal monitoring to primary care. However, building big data-enabled systems carries on relevant implications in terms of reproducibility of research studies and management of privacy and data access; proper actions should be taken to deal with these issues. An interesting consequence of the big data scenario is the availability of new software, methods, and tools, such as map-reduce, cloud computing, and concept drift machine learning algorithms, which will not only contribute to big data research, but may be beneficial in many biomedical informatics applications. The way forward with the big data opportunity will require properly applied engineering principles to design studies and applications, to avoid preconceptions or over-enthusiasms, to fully exploit the available technologies, and to improve data processing and data management regulations. PMID:24853034

  20. Big data and biomedical informatics: a challenging opportunity.

    Science.gov (United States)

    Bellazzi, R

    2014-05-22

    Big data are receiving an increasing attention in biomedicine and healthcare. It is therefore important to understand the reason why big data are assuming a crucial role for the biomedical informatics community. The capability of handling big data is becoming an enabler to carry out unprecedented research studies and to implement new models of healthcare delivery. Therefore, it is first necessary to deeply understand the four elements that constitute big data, namely Volume, Variety, Velocity, and Veracity, and their meaning in practice. Then, it is mandatory to understand where big data are present, and where they can be beneficially collected. There are research fields, such as translational bioinformatics, which need to rely on big data technologies to withstand the shock wave of data that is generated every day. Other areas, ranging from epidemiology to clinical care, can benefit from the exploitation of the large amounts of data that are nowadays available, from personal monitoring to primary care. However, building big data-enabled systems carries on relevant implications in terms of reproducibility of research studies and management of privacy and data access; proper actions should be taken to deal with these issues. An interesting consequence of the big data scenario is the availability of new software, methods, and tools, such as map-reduce, cloud computing, and concept drift machine learning algorithms, which will not only contribute to big data research, but may be beneficial in many biomedical informatics applications. The way forward with the big data opportunity will require properly applied engineering principles to design studies and applications, to avoid preconceptions or over-enthusiasms, to fully exploit the available technologies, and to improve data processing and data management regulations.

  1. Telerehabilitation Clinical and Vocational Applications for Assistive Technology: Research, Opportunities, and Challenges

    Directory of Open Access Journals (Sweden)

    Mark R. Schmeler

    2009-09-01

    Full Text Available Rehabilitation service providers in rural or underserved areas are often challenged in meeting the needs of their complex patients due to limited resources in their geographical area. Recruitment and retention of the rural clinical workforce are beset by the ongoing problems associated with limited continuing education opportunities, professional isolation, and the challenges inherent in coordinating rural community healthcare. People with disabilities who live in rural communities also face challenges accessing healthcare. Traveling long distances to a specialty clinic for necessary expertise may be troublesome due to inadequate or unavailable transportation, disability specific limitations, and financial limitations. Distance and lack of access are just two threats to quality of care that now being addressed by the use of videoconferencing, information exchange, and other telecommunication technologies that facilitate telerehabilitation. This white paper illustrates and summarizes clinical and vocational applications of telerehabilitation. We provide definitions related to the fields of telemedicine, telehealth, and telerehabilitation, and consider the impetus for telerehabilitation. We review the telerehabilitation literature for assistive technology applications; pressure ulcer prevention; virtual reality applications; speech-language pathology applications; seating and wheeled mobility applications; vocational rehabilitation applications; and cost effectiveness. We then discuss external telerehabilitation influencers, such as the positions of professional organizations. Finally, we summarize clinical and policy issues in a limited context appropriate to the scope of this paper. Keywords: Telerehabilitation, Telehealth, Telemedicine, Telepractice

  2. Telerehabilitation clinical and vocational applications for assistive technology: research, opportunities, and challenges.

    Science.gov (United States)

    Schmeler, Mark R; Schein, Richard M; McCue, Michael; Betz, Kendra

    2009-01-01

    Rehabilitation service providers in rural or underserved areas are often challenged in meeting the needs of their complex patients due to limited resources in their geographical area. Recruitment and retention of the rural clinical workforce are beset by the ongoing problems associated with limited continuing education opportunities, professional isolation, and the challenges inherent in coordinating rural community healthcare. People with disabilities who live in rural communities also face challenges accessing healthcare. Traveling long distances to a specialty clinic for necessary expertise may be troublesome due to inadequate or unavailable transportation, disability specific limitations, and financial limitations. Distance and lack of access are just two threats to quality of care that now being addressed by the use of videoconferencing, information exchange, and other telecommunication technologies that facilitate telerehabilitation. This white paper illustrates and summarizes clinical and vocational applications of telerehabilitation. We provide definitions related to the fields of telemedicine, telehealth, and telerehabilitation, and consider the impetus for telerehabilitation. We review the telerehabilitation literature for assistive technology applications; pressure ulcer prevention; virtual reality applications; speech-language pathology applications; seating and wheeled mobility applications; vocational rehabilitation applications; and cost-effectiveness. We then discuss external telerehabilitation influencers, such as the positions of professional organizations. Finally, we summarize clinical and policy issues in a limited context appropriate to the scope of this paper.

  3. Nanotechnology in the Chemical Industry - Opportunities and Challenges

    International Nuclear Information System (INIS)

    Qian Qiuzhao; Boxman, Arthur; Chowdhry, Uma

    2003-01-01

    The traditional chemical industry has become a largely mature industry with many commodity products based on established technologies. Therefore, new product and market opportunities will more likely come from speciality chemicals, and from new functionalities obtained from new processing technologies as well as new microstructure control methodologies. It is a well-known fact that in addition to its molecular structure, the microstructure of a material is key to determining its properties. Controlling structures at the micro- and nano-levels is therefore essential to new discoveries. For this article, we define nanotechnology as the controlled manipulation of nanomaterials with at least one dimension less than 100nm.Nanotechnology is emerging as one of the principal areas of investigation that is integrating chemistry and materials science, and in some cases integrating these with biology to create new and yet undiscovered properties that can be exploited to gain new market opportunities. In this article market opportunities for nanotechnology will be presented from an industrial perspective covering electronic, biomedical, performance materials, and consumer products. Manufacturing technology challenges will be identified, including operations ranging from particle formation, coating, dispersion, to characterization, modeling, and simulation. Finally, a nanotechnology innovation roadmap is proposed wherein the interplay between the development of nanoscale building blocks, product design, process design, and value chain integration is identified. A suggestion is made for an R and D model combining market pull and technology push as a way to quickly exploit the advantages in nanotechnology and translate these into customer benefits

  4. The opportunity to collaborate increases preschoolers' motivation for challenging tasks.

    Science.gov (United States)

    Butler, Lucas P; Walton, Gregory M

    2013-12-01

    Collaborating on challenging endeavors is a foundation of human society. Recent research suggests that young children are not only motivated to cooperate with others-for instance, to help others accomplish their goals-but may also be motivated to collaborate with others-to pursue shared goals. However, a primary reason why collaboration is so important is because opportunities to collaborate can bring people together to work hard to overcome challenges. Two studies (N=70) tested whether the collaborative nature of an activity itself can cause preschoolers to enjoy challenging tasks more and to persist longer on them. To isolate the psychological feeling of collaboration, we tested this hypothesis by manipulating purely psychological cues of collaboration; in all cases, children worked while physically alone. Both studies found that such cues substantially increased preschoolers' motivation on a challenging puzzle, including their persistence on and liking for the puzzle, relative to two non-collaborative control conditions. We suggest that an early emerging drive to engage in shared collaborative activities leads children to find collaborative activities to be intrinsically motivating. This may represent an important basis of motivation as children embark on formal schooling. Copyright © 2013 Elsevier Inc. All rights reserved.

  5. Big data in complex systems challenges and opportunities

    CERN Document Server

    Azar, Ahmad; Snasael, Vaclav; Kacprzyk, Janusz; Abawajy, Jemal

    2015-01-01

    This volume provides challenges and Opportunities with updated, in-depth material on the application of Big data to complex systems in order to find solutions for the challenges and problems facing big data sets applications. Much data today is not natively in structured format; for example, tweets and blogs are weakly structured pieces of text, while images and video are structured for storage and display, but not for semantic content and search. Therefore transforming such content into a structured format for later analysis is a major challenge. Data analysis, organization, retrieval, and modeling are other  foundational challenges treated in this book. The material of this book will be useful for researchers and practitioners in the field of big data as well as advanced undergraduate and graduate  students. Each of the 17 chapters in the book opens with a chapter abstract and key terms list. The chapters are organized along the lines of problem description, related works, and analysis of the results and ...

  6. Pediatric palliative care and pediatric medical ethics: opportunities and challenges.

    Science.gov (United States)

    Feudtner, Chris; Nathanson, Pamela G

    2014-02-01

    The fields of pediatric palliative care (PPC) and pediatric medical ethics (PME) overlap substantially, owing to a variety of historical, cultural, and social factors. This entwined relationship provides opportunities for leveraging the strong communication skills of both sets of providers, as well as the potential for resource sharing and research collaboration. At the same time, the personal and professional relationships between PPC and PME present challenges, including potential conflict with colleagues, perceived or actual bias toward a palliative care perspective in resolving ethical problems, potential delay or underuse of PME services, and a potential undervaluing of the medical expertise required for PPC consultation. We recommend that these challenges be managed by: (1) clearly defining and communicating clinical roles of PPC and PME staff, (2) developing questions that may prompt PPC and PME teams to request consultation from the other service, (3) developing explicit recusal criteria for PPC providers who also provide PME consultation, (4) ensuring that PPC and PME services remain organizationally distinct, and (5) developing well-defined and broad scopes of practice. Overall, the rich relationship between PPC and PME offers substantial opportunities to better serve patients and families facing difficult decisions.

  7. Political communication research: New media, new challenges, and new opportunities

    Directory of Open Access Journals (Sweden)

    Rasmus Kleis Nielsen

    2014-06-01

    Full Text Available The rise of new media and the broader set of social changes they are part of present political communication research with new challenges and new opportunities at a time when many think the field is at an intellectual impasse (e.g., Bennett & Iyengar, 2008. In this article, I argue that parts of the field’s problems are rooted in the way in which political communication research has developed since the 1960s. In this period, the field has moved from being interdisciplinary and mixed-methods to being more homogenous and narrowly focused, based primarily on ideas developed in social psychology, certain strands of political science, and the effects-tradition of mass communication research. This dominant paradigm has contributed much to our understanding of some aspects of political communication. But it is struggling to make sense of many others, including questions concerning people’s experience of political communication processes and questions concerning the symbolic, institutional, and technological nature of these processes—especially during a time of often rapid change. To overcome this problem, I argue that the field of political communication research should re-engage with the rest of media and communication studies and embrace a broader and more diverse agenda. I discuss audience research and journalism studies as examples of adjacent fields that use a more diverse range of theoretical and methodological tools that might help political communication research engage with new media and the new challenges and new opportunities for research that they represent.

  8. Mapping opportunities and challenges for rewilding in Europe.

    Science.gov (United States)

    Ceaușu, Silvia; Hofmann, Max; Navarro, Laetitia M; Carver, Steve; Verburg, Peter H; Pereira, Henrique M

    2015-08-01

    Farmland abandonment takes place across the world due to socio-economic and ecological drivers. In Europe agricultural and environmental policies aim to prevent abandonment and halt ecological succession. Ecological rewilding has been recently proposed as an alternative strategy. We developed a framework to assess opportunities for rewilding across different dimensions of wilderness in Europe. We mapped artificial light, human accessibility based on transport infrastructure, proportion of harvested primary productivity (i.e., ecosystem productivity appropriated by humans through agriculture or forestry), and deviation from potential natural vegetation in areas projected to be abandoned by 2040. At the continental level, the levels of artificial light were low and the deviation from potential natural vegetation was high in areas of abandonment. The relative importance of wilderness metrics differed regionally and was strongly connected to local environmental and socio-economic contexts. Large areas of projected abandonment were often located in or around Natura 2000 sites. Based on these results, we argue that management should be tailored to restore the aspects of wilderness that are lacking in each region. There are many remaining challenges regarding biodiversity in Europe, but megafauna species are already recovering. To further potentiate large-scale rewilding, Natura 2000 management would need to incorporate rewilding approaches. Our framework can be applied to assessing rewilding opportunities and challenges in other world regions, and our results could guide redirection of subsidies to manage social-ecological systems. © 2015 The Authors. Conservation Biology published by wiley Periodicals, Inc. on behalf of the Society for Conservation Biology.

  9. Opportunities and challenges for public libraries to enhance community resilience.

    Science.gov (United States)

    Veil, Shari R; Bishop, Bradley Wade

    2014-04-01

    This study bridges a gap between public library and emergency management policy versus practice by examining the role of public libraries in the community resource network for disaster recovery. Specifically, this study identifies the opportunities and challenges for public libraries to fulfill their role as a FEMA-designated essential community organization and enhance community resilience. The results indicate there are several opportunities for libraries to enhance community resilience by offering technology resources and assistance; providing office, meeting, and community living room space; serving as the last redundant communication channel and a repository for community information and disaster narratives; and adapting or expanding services already offered to meet the changing needs of the community. However, libraries also face challenges in enhancing community resilience, including the temptation to overcommit library capacity and staff capability beyond the library mission and a lack of long-term disaster plans and collaboration with emergency managers and government officials. Implications for library and emergency management practice and crisis research are discussed. © 2013 Society for Risk Analysis.

  10. Big Data in Designing Clinical Trials: Opportunities and Challenges.

    Science.gov (United States)

    Mayo, Charles S; Matuszak, Martha M; Schipper, Matthew J; Jolly, Shruti; Hayman, James A; Ten Haken, Randall K

    2017-01-01

    Emergence of big data analytics resource systems (BDARSs) as a part of routine practice in Radiation Oncology is on the horizon. Gradually, individual researchers, vendors, and professional societies are leading initiatives to create and demonstrate use of automated systems. What are the implications for design of clinical trials, as these systems emerge? Gold standard, randomized controlled trials (RCTs) have high internal validity for the patients and settings fitting constraints of the trial, but also have limitations including: reproducibility, generalizability to routine practice, infrequent external validation, selection bias, characterization of confounding factors, ethics, and use for rare events. BDARS present opportunities to augment and extend RCTs. Preliminary modeling using single- and muti-institutional BDARS may lead to better design and less cost. Standardizations in data elements, clinical processes, and nomenclatures used to decrease variability and increase veracity needed for automation and multi-institutional data pooling in BDARS also support ability to add clinical validation phases to clinical trial design and increase participation. However, volume and variety in BDARS present other technical, policy, and conceptual challenges including applicable statistical concepts, cloud-based technologies. In this summary, we will examine both the opportunities and the challenges for use of big data in design of clinical trials.

  11. Big Data in Designing Clinical Trials: Opportunities and Challenges

    Directory of Open Access Journals (Sweden)

    Charles S. Mayo

    2017-08-01

    Full Text Available Emergence of big data analytics resource systems (BDARSs as a part of routine practice in Radiation Oncology is on the horizon. Gradually, individual researchers, vendors, and professional societies are leading initiatives to create and demonstrate use of automated systems. What are the implications for design of clinical trials, as these systems emerge? Gold standard, randomized controlled trials (RCTs have high internal validity for the patients and settings fitting constraints of the trial, but also have limitations including: reproducibility, generalizability to routine practice, infrequent external validation, selection bias, characterization of confounding factors, ethics, and use for rare events. BDARS present opportunities to augment and extend RCTs. Preliminary modeling using single- and muti-institutional BDARS may lead to better design and less cost. Standardizations in data elements, clinical processes, and nomenclatures used to decrease variability and increase veracity needed for automation and multi-institutional data pooling in BDARS also support ability to add clinical validation phases to clinical trial design and increase participation. However, volume and variety in BDARS present other technical, policy, and conceptual challenges including applicable statistical concepts, cloud-based technologies. In this summary, we will examine both the opportunities and the challenges for use of big data in design of clinical trials.

  12. Processing Challenges and Opportunities of Camel Dairy Products

    Directory of Open Access Journals (Sweden)

    Tesfemariam Berhe

    2017-01-01

    Full Text Available A review on the challenges and opportunities of processing camel milk into dairy products is provided with an objective of exploring the challenges of processing and assessing the opportunities for developing functional products from camel milk. The gross composition of camel milk is similar to bovine milk. Nonetheless, the relative composition, distribution, and the molecular structure of the milk components are reported to be different. Consequently, manufacturing of camel dairy products such as cheese, yoghurt, or butter using the same technology as for dairy products from bovine milk can result in processing difficulties and products of inferior quality. However, scientific evidence points to the possibility of transforming camel milk into products by optimization of the processing parameters. Additionally, camel milk has traditionally been used for its medicinal values and recent scientific studies confirm that it is a rich source of bioactive, antimicrobial, and antioxidant substances. The current literature concerning product design and functional potential of camel milk is fragmented in terms of time, place, and depth of the research. Therefore, it is essential to understand the fundamental features of camel milk and initiate detailed multidisciplinary research to fully explore and utilize its functional and technological properties.

  13. Urban Big Data and Sustainable Development Goals: Challenges and Opportunities

    Directory of Open Access Journals (Sweden)

    Ali Kharrazi

    2016-12-01

    Full Text Available Cities are perhaps one of the most challenging and yet enabling arenas for sustainable development goals. The Sustainable Development Goals (SDGs emphasize the need to monitor each goal through objective targets and indicators based on common denominators in the ability of countries to collect and maintain relevant standardized data. While this approach is aimed at harmonizing the SDGs at the national level, it presents unique challenges and opportunities for the development of innovative urban-level metrics through big data innovations. In this article, we make the case for advancing more innovative targets and indicators relevant to the SDGs through the emergence of urban big data. We believe that urban policy-makers are faced with unique opportunities to develop, experiment, and advance big data practices relevant to sustainable development. This can be achieved by situating the application of big data innovations through developing mayoral institutions for the governance of urban big data, advancing the culture and common skill sets for applying urban big data, and investing in specialized research and education programs.

  14. Urban solid waste management in Chongqing: Challenges and opportunities

    International Nuclear Information System (INIS)

    Yuan Hui; Wang Li'ao; Su Fenwei; Hu Gang

    2006-01-01

    The dual influences of the resource supply and protection in ecological environments will pose a significant challenge to China's sustainable development. Solid waste management offers opportunities to improve profits by conserving resources and improving environmental performance. This paper examines municipal solid waste (MSW) management in urban Chongqing, the nation's fourth largest municipality after Beijing, Shanghai and Tianjin. In this paper, we will provide information on the quantity and composition of MSW, as well as give an overview of different methods for collection, transport, treatment and disposal of MSW. At present the daily amount of MSW generated per person is about 1.08 kg; food waste accounts for about 59% of total MSW. MSW in Chongqing has a higher moisture content (64.1%) and a lower LHV (3728 kJ/kg) than other cities in Asia, which is an obstruction for incineration. Landfills are the main method of disposal in Chongqing, but pollution caused by simple landfills and lack of backup MSW disposal capacity are becoming major problems in the main districts of Chongqing. In this paper, the challenges being faced and opportunities to MSW in Chongqing are analyzed and some suggestions are given for improving the MSW system in the future

  15. Medical doctors in healthcare leadership: theoretical and practical challenges.

    Science.gov (United States)

    Denis, Jean-Louis; van Gestel, Nicolette

    2016-05-24

    While healthcare systems vary in their structure and available resources, it is widely recognized that medical doctors play a key role in their adaptation and performance. In this article, we examine recent government and organizational policies in two different health systems that aim to develop clinical leadership among the medical profession. Clinical leadership refers to the engagement and guiding role of physicians in health system improvement. Three dimensions are defined to conduct our analysis of engaging medical doctors in healthcare leadership: the position and status of medical doctors within the system; the broader institutional context of governmental and organizational policies to engage medical doctors in clinical leadership roles; and the main factors that may facilitate or limit achievements. Our aim in this study is exploratory. We selected two contrasting cases according to their level of institutional pluralism: one national health insurance system, Canada, and one etatist social insurance system, the Netherlands. We documented the institutional dynamics of medical doctors' engagement and leadership through secondary sources, such as government websites, key policy reports, and scholarly literature on health policies in both countries. Initiatives across Canadian provinces signal that the medical profession and governments search for alternatives to involve doctors in health system improvement beyond the limitations imposed by their fundamental social contract and formal labour relations. These initiatives suggest an emerging trend toward more joint collaboration between governments and medical associations. In the Dutch system, organizational and legal attempts for integration over the past decades do not yet fit well with the ideas and interests of medical doctors. The engagement of medical doctors requires additional initiatives that are closer to their professional values and interests and that depart from an overly focus on top down

  16. Iterative near-term ecological forecasting: Needs, opportunities, and challenges

    Science.gov (United States)

    Dietze, Michael C.; Fox, Andrew; Beck-Johnson, Lindsay; Betancourt, Julio L.; Hooten, Mevin B.; Jarnevich, Catherine S.; Keitt, Timothy H.; Kenney, Melissa A.; Laney, Christine M.; Larsen, Laurel G.; Loescher, Henry W.; Lunch, Claire K.; Pijanowski, Bryan; Randerson, James T.; Read, Emily; Tredennick, Andrew T.; Vargas, Rodrigo; Weathers, Kathleen C.; White, Ethan P.

    2018-01-01

    Two foundational questions about sustainability are “How are ecosystems and the services they provide going to change in the future?” and “How do human decisions affect these trajectories?” Answering these questions requires an ability to forecast ecological processes. Unfortunately, most ecological forecasts focus on centennial-scale climate responses, therefore neither meeting the needs of near-term (daily to decadal) environmental decision-making nor allowing comparison of specific, quantitative predictions to new observational data, one of the strongest tests of scientific theory. Near-term forecasts provide the opportunity to iteratively cycle between performing analyses and updating predictions in light of new evidence. This iterative process of gaining feedback, building experience, and correcting models and methods is critical for improving forecasts. Iterative, near-term forecasting will accelerate ecological research, make it more relevant to society, and inform sustainable decision-making under high uncertainty and adaptive management. Here, we identify the immediate scientific and societal needs, opportunities, and challenges for iterative near-term ecological forecasting. Over the past decade, data volume, variety, and accessibility have greatly increased, but challenges remain in interoperability, latency, and uncertainty quantification. Similarly, ecologists have made considerable advances in applying computational, informatic, and statistical methods, but opportunities exist for improving forecast-specific theory, methods, and cyberinfrastructure. Effective forecasting will also require changes in scientific training, culture, and institutions. The need to start forecasting is now; the time for making ecology more predictive is here, and learning by doing is the fastest route to drive the science forward.

  17. Learner-Adaptive Educational Technology for Simulation in Healthcare: Foundations and Opportunities.

    Science.gov (United States)

    Lineberry, Matthew; Dev, Parvati; Lane, H Chad; Talbot, Thomas B

    2018-06-01

    Despite evidence that learners vary greatly in their learning needs, practical constraints tend to favor ''one-size-fits-all'' educational approaches, in simulation-based education as elsewhere. Adaptive educational technologies - devices and/or software applications that capture and analyze relevant data about learners to select and present individually tailored learning stimuli - are a promising aid in learners' and educators' efforts to provide learning experiences that meet individual needs. In this article, we summarize and build upon the 2017 Society for Simulation in Healthcare Research Summit panel discussion on adaptive learning. First, we consider the role of adaptivity in learning broadly. We then outline the basic functions that adaptive learning technologies must implement and the unique affordances and challenges of technology-based approaches for those functions, sharing an illustrative example from healthcare simulation. Finally, we consider future directions for accelerating research, development, and deployment of effective adaptive educational technology and techniques in healthcare simulation.

  18. Emergence of 3D Printed Dosage Forms: Opportunities and Challenges.

    Science.gov (United States)

    Alhnan, Mohamed A; Okwuosa, Tochukwu C; Sadia, Muzna; Wan, Ka-Wai; Ahmed, Waqar; Arafat, Basel

    2016-08-01

    The recent introduction of the first FDA approved 3D-printed drug has fuelled interest in 3D printing technology, which is set to revolutionize healthcare. Since its initial use, this rapid prototyping (RP) technology has evolved to such an extent that it is currently being used in a wide range of applications including in tissue engineering, dentistry, construction, automotive and aerospace. However, in the pharmaceutical industry this technology is still in its infancy and its potential yet to be fully explored. This paper presents various 3D printing technologies such as stereolithographic, powder based, selective laser sintering, fused deposition modelling and semi-solid extrusion 3D printing. It also provides a comprehensive review of previous attempts at using 3D printing technologies on the manufacturing dosage forms with a particular focus on oral tablets. Their advantages particularly with adaptability in the pharmaceutical field have been highlighted, which enables the preparation of dosage forms with complex designs and geometries, multiple actives and tailored release profiles. An insight into the technical challenges facing the different 3D printing technologies such as the formulation and processing parameters is provided. Light is also shed on the different regulatory challenges that need to be overcome for 3D printing to fulfil its real potential in the pharmaceutical industry.

  19. Climate Change Adaptation Challenges and EO Business Opportunities

    Science.gov (United States)

    Lopez-Baeza, Ernesto; Mathieu, Pierre-Philippe; Bansal, Rahul; Del Rey, Maria; Mohamed, Ebrahim; Ruiz, Paz; Signes, Marcos

    Climate change is one of the defining challenges of the 21st century, but is no longer a matter of just scientific concern. It encompasses economics, sociology, global politics as well as national and local politics, law, health and environmental security, etc. The challenge of facing the impacts of climate change is often framed in terms of two potential paths that civilization might take: mitigation and adaptation. On the one hand, mitigation involves reducing the magnitude of climate change itself and is composed of emissions reductions and geoengineering. On the other hand and by contrast, adaptation involves efforts to limit our vulnerability to climate change impacts through various measures. It refers to our ability to adjust ourselves to climate change -including climate variability and extremes, to moderate potential damage, to take advantage of opportunities, or to cope with the consequences. Therefore, we are now faced with a double challenge: next to deep cuts in greenhouse gas emissions, we also need to adapt to the changing climate conditions. The use of satellites to monitor processes and trends at the global scale is essential in the context of climate change. Earth Observation has the potential to improve our predictive vision and to advance climate models. Space sciences and technologies constitute a significant issue in Education and Public Awareness of Science. Space missions face the probably largest scientific and industrial challenges of humanity. It is thus a fact that space drives innovation in the major breakthrough and cutting edge technological advances of mankind (techniques, processes, new products, … as well as in markets and business models). Technology and innovation is the basis of all space activities. Space agencies offer an entire range of space-related activities - from space science and environmental monitoring to industrial competitiveness and end-user services. More specifically, Earth Observation satellites have a unique

  20. Patient level costing in Ireland: process, challenges and opportunities.

    Science.gov (United States)

    Murphy, A; McElroy, B

    2015-03-01

    In 2013, the Department of Health released their policy paper on hospital financing entitled Money Follows the Patient. A fundamental building block for the proposed financing model is patient level costing. This paper outlines the patient level costing process, identifies the opportunities and considers the challenges associated with the process in the Irish hospital setting. Methods involved a review of the existing literature which was complemented with an interview with health service staff. There are considerable challenges associated with implementing patient level costing including deficits in information and communication technologies and financial expertise as well as timeliness of coding. In addition, greater clinical input into the costing process is needed compared to traditional costing processes. However, there are long-term benefits associated with patient level costing; these include empowerment of clinical staff, improved transparency and price setting and greater fairness, especially in the treatment of outliers. These can help to achieve the Government's Health Strategy. The benefits of patient level costing need to be promoted and a commitment to investment in overcoming the challenges is required.

  1. Remote sensing of ecosystem health: opportunities, challenges, and future perspectives.

    Science.gov (United States)

    Li, Zhaoqin; Xu, Dandan; Guo, Xulin

    2014-11-07

    Maintaining a healthy ecosystem is essential for maximizing sustainable ecological services of the best quality to human beings. Ecological and conservation research has provided a strong scientific background on identifying ecological health indicators and correspondingly making effective conservation plans. At the same time, ecologists have asserted a strong need for spatially explicit and temporally effective ecosystem health assessments based on remote sensing data. Currently, remote sensing of ecosystem health is only based on one ecosystem attribute: vigor, organization, or resilience. However, an effective ecosystem health assessment should be a comprehensive and dynamic measurement of the three attributes. This paper reviews opportunities of remote sensing, including optical, radar, and LiDAR, for directly estimating indicators of the three ecosystem attributes, discusses the main challenges to develop a remote sensing-based spatially-explicit comprehensive ecosystem health system, and provides some future perspectives. The main challenges to develop a remote sensing-based spatially-explicit comprehensive ecosystem health system are: (1) scale issue; (2) transportability issue; (3) data availability; and (4) uncertainties in health indicators estimated from remote sensing data. However, the Radarsat-2 constellation, upcoming new optical sensors on Worldview-3 and Sentinel-2 satellites, and improved technologies for the acquisition and processing of hyperspectral, multi-angle optical, radar, and LiDAR data and multi-sensoral data fusion may partly address the current challenges.

  2. Remote Sensing of Ecosystem Health: Opportunities, Challenges, and Future Perspectives

    Directory of Open Access Journals (Sweden)

    Zhaoqin Li

    2014-11-01

    Full Text Available Maintaining a healthy ecosystem is essential for maximizing sustainable ecological services of the best quality to human beings. Ecological and conservation research has provided a strong scientific background on identifying ecological health indicators and correspondingly making effective conservation plans. At the same time, ecologists have asserted a strong need for spatially explicit and temporally effective ecosystem health assessments based on remote sensing data. Currently, remote sensing of ecosystem health is only based on one ecosystem attribute: vigor, organization, or resilience. However, an effective ecosystem health assessment should be a comprehensive and dynamic measurement of the three attributes. This paper reviews opportunities of remote sensing, including optical, radar, and LiDAR, for directly estimating indicators of the three ecosystem attributes, discusses the main challenges to develop a remote sensing-based spatially-explicit comprehensive ecosystem health system, and provides some future perspectives. The main challenges to develop a remote sensing-based spatially-explicit comprehensive ecosystem health system are: (1 scale issue; (2 transportability issue; (3 data availability; and (4 uncertainties in health indicators estimated from remote sensing data. However, the Radarsat-2 constellation, upcoming new optical sensors on Worldview-3 and Sentinel-2 satellites, and improved technologies for the acquisition and processing of hyperspectral, multi-angle optical, radar, and LiDAR data and multi-sensoral data fusion may partly address the current challenges.

  3. Opportunities and Challenges in Deep Mining: A Brief Review

    Directory of Open Access Journals (Sweden)

    Pathegama G. Ranjith

    2017-08-01

    Full Text Available Mineral consumption is increasing rapidly as more consumers enter the market for minerals and as the global standard of living increases. As a result, underground mining continues to progress to deeper levels in order to tackle the mineral supply crisis in the 21st century. However, deep mining occurs in a very technical and challenging environment, in which significant innovative solutions and best practice are required and additional safety standards must be implemented in order to overcome the challenges and reap huge economic gains. These challenges include the catastrophic events that are often met in deep mining engineering: rockbursts, gas outbursts, high in situ and redistributed stresses, large deformation, squeezing and creeping rocks, and high temperature. This review paper presents the current global status of deep mining and highlights some of the newest technological achievements and opportunities associated with rock mechanics and geotechnical engineering in deep mining. Of the various technical achievements, unmanned working-faces and unmanned mines based on fully automated mining and mineral extraction processes have become important fields in the 21st century.

  4. Remote Sensing of Ecosystem Health: Opportunities, Challenges, and Future Perspectives

    Science.gov (United States)

    Li, Zhaoqin; Xu, Dandan; Guo, Xulin

    2014-01-01

    Maintaining a healthy ecosystem is essential for maximizing sustainable ecological services of the best quality to human beings. Ecological and conservation research has provided a strong scientific background on identifying ecological health indicators and correspondingly making effective conservation plans. At the same time, ecologists have asserted a strong need for spatially explicit and temporally effective ecosystem health assessments based on remote sensing data. Currently, remote sensing of ecosystem health is only based on one ecosystem attribute: vigor, organization, or resilience. However, an effective ecosystem health assessment should be a comprehensive and dynamic measurement of the three attributes. This paper reviews opportunities of remote sensing, including optical, radar, and LiDAR, for directly estimating indicators of the three ecosystem attributes, discusses the main challenges to develop a remote sensing-based spatially-explicit comprehensive ecosystem health system, and provides some future perspectives. The main challenges to develop a remote sensing-based spatially-explicit comprehensive ecosystem health system are: (1) scale issue; (2) transportability issue; (3) data availability; and (4) uncertainties in health indicators estimated from remote sensing data. However, the Radarsat-2 constellation, upcoming new optical sensors on Worldview-3 and Sentinel-2 satellites, and improved technologies for the acquisition and processing of hyperspectral, multi-angle optical, radar, and LiDAR data and multi-sensoral data fusion may partly address the current challenges. PMID:25386759

  5. Learning in professionally 'distant' contexts: opportunities and challenges.

    Science.gov (United States)

    Mausz, Justin; Tavares, Walter

    2017-08-01

    The changing nature of healthcare education and delivery is such that clinicians will increasingly find themselves practicing in contexts that are physically and/or conceptually different from the settings in which they were trained, a practice that conflicts on some level with socio-cultural theories of learning that emphasize learning in context. Our objective was therefore to explore learning in 'professionally distant' contexts. Using paramedic education, where portions of training occur in hospital settings despite preparing students for out-of-hospital work, fifty-three informants (11 current students, 13 recent graduates, 16 paramedic program faculty and 13 program coordinators/directors) took part in five semi-structured focus groups. Participants reflected on the value and role of hospital placements in paramedic student development. All sessions were audio recorded, transcribed verbatim and analyzed using inductive thematic analysis. In this context six educational advantages and two challenges were identified when using professionally distant learning environments. Learning could still be associated with features such as (a) engagement through "authenticity", (b) technical skill development, (c) interpersonal skill development, (d) psychological resilience, (e) healthcare system knowledge and (f) scaffolding. Variability in learning and misalignment with learning goals were identified as potential threats. Learning environments that are professionally distant from eventual practice settings may prove meaningful by providing learners with foundational and preparatory learning experiences for competencies that may be transferrable. This suggests that where learning occurs may be less important than how the experience contributes to the learner's development and the meaning or value he/she derives from it.

  6. Social media as marketing tool for SMEs: opportunities and challenges

    Directory of Open Access Journals (Sweden)

    Blerta Rugova

    2016-11-01

    Full Text Available Social media is a phenomenon that has transformed the interaction and communication of individuals throughout the world. Especially, social networking websites are very popular and have become daily practice in a lot of people’s lives. These sites have made significant impact on the individual’s life. However, social media is not only a communication tool for amusement, but it is also an important part of marketing strategies in business life. There is a constant rise in social networking and therefore impact of social networks is becoming stronger every day, into each kind of business. Social media are often used as a source of information and spread of knowledge changing people’s views and opinions. They belong among very important business marketing tactics and help to create new business opportunities, develop a stronger market position or modify consumer’s behaviour. Therefore, in developed countries, social media are gaining popularity and are increasingly used in regular operations of many companies, including start-ups, small, medium-sized, and large organizations. But it seems that in emerging economies such as Kosovo, Albania and other neighbour countries, marketing over social media is not taken that seriously, especially by SMEs. There are some companies who have shown interest and have created their presence, yet there is no serious focus in this innovative marketing tool. The study deals with the issue of social media and its influence on SMEs. It classifies social media and explores the possibilities and challenges of social networks in business. The authors describe features and the evolution of social media, including major social networking sites that came into existence during the 21st century. The purpose of the paper is to review the academic literature on the opportunities and challenges of using social media from SMEs, as well as identifying factors that drive social media marketing adoption and usage in SMEs. This

  7. Advance Directives in Hospice Healthcare Providers: A Clinical Challenge.

    Science.gov (United States)

    Luck, George R; Eggenberger, Terry; Newman, David; Cortizo, Jacqueline; Blankenship, Derek C; Hennekens, Charles H

    2017-11-01

    On a daily basis, healthcare providers, especially those dealing with terminally ill patients, such as hospice workers, witness how advance directives help ensure the wishes of patients. They also witness the deleterious consequences when patients fail to document the care they desire at their end of life. To the best of our knowledge there are no data concerning the prevalence of advance directives among hospice healthcare providers. We therefore explored the prevalence and factors influencing completion rates in a survey of hospice healthcare providers. Surveys that included 32 items to explore completion rates, as well as barriers, knowledge, and demographics, were e-mailed to 2097 healthcare providers, including employees and volunteers, at a nonprofit hospice. Of 890 respondents, 44% reported having completed an advance directive. Ethnicity, age, relationship status, and perceived knowledge were all significant factors influencing the completion rates, whereas years of experience or working directly with patients had no effect. Procrastination, fear of the subject, and costs were common reasons reported as barriers. Upon completion of the survey, 43% said they will now complete an advance directive, and 45% will talk to patients and families about their wishes. The majority of hospice healthcare providers have not completed an advance directive. These results are very similar to those for other healthcare providers treating patients with terminal diseases, specifically oncologists. Because, at completion, 43% said that they would now complete an advance directive, such a survey of healthcare providers may help increase completion rates. Copyright © 2017 Elsevier Inc. All rights reserved.

  8. Sustainable ground transportation – review of technologies, challenges and opportunities

    Energy Technology Data Exchange (ETDEWEB)

    Agarwal, Ramesh K. [Department of Mechanical Engineering and Materials Science, Washington University, St. Louis, MO 63130 (United States)

    2013-07-01

    Currently there are nearly 750 million ground vehicles in service worldwide. They are responsible for 50% of petroleum (oil) consumption and 60% of all greenhouse gas (GHG) emissions worldwide. The number of vehicles is forecasted to double by 2050. Therefore the environmental issues such as noise, emissions and fuel burn have become important for energy and environmental sustainability. This paper provides an overview of specific energy and environmental issues related to ground transportation. The technologies related to reduction in energy requirements such as reducing the vehicle mass by using the high strength low weight materials and reducing the viscous drag by active flow control and smoothing the operational profile, and reducing the contact friction by special tire materials are discussed along with the portable energy sources for reducing the GHG emissions such as low carbon fuels (biofuels), Lithium-ion batteries with high energy density and stability, and fuel cells. The technological challenges and opportunities for innovations are discussed.

  9. Miniaturizing EM Sample Preparation: Opportunities, Challenges, and "Visual Proteomics".

    Science.gov (United States)

    Arnold, Stefan A; Müller, Shirley A; Schmidli, Claudio; Syntychaki, Anastasia; Rima, Luca; Chami, Mohamed; Stahlberg, Henning; Goldie, Kenneth N; Braun, Thomas

    2018-03-01

    This review compares and discusses conventional versus miniaturized specimen preparation methods for transmission electron microscopy (TEM). The progress brought by direct electron detector cameras, software developments and automation have transformed transmission cryo-electron microscopy (cryo-EM) and made it an invaluable high-resolution structural analysis tool. In contrast, EM specimen preparation has seen very little progress in the last decades and is now one of the main bottlenecks in cryo-EM. Here, we discuss the challenges faced by specimen preparation for single particle EM, highlight current developments, and show the opportunities resulting from the advanced miniaturized and microfluidic sample grid preparation methods described, such as visual proteomics and time-resolved cryo-EM studies. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  10. Anaerobic digestion of microalgal biomass: Challenges, opportunities and research needs.

    Science.gov (United States)

    Gonzalez-Fernandez, Cristina; Sialve, Bruno; Molinuevo-Salces, Beatriz

    2015-12-01

    Integration of anaerobic digestion (AD) with microalgae processes has become a key topic to support economic and environmental development of this resource. Compared with other substrates, microalgae can be produced close to the plant without the need for arable lands and be fully integrated within a biorefinery. As a limiting step, anaerobic hydrolysis appears to be one of the most challenging steps to reach a positive economic balance and to completely exploit the potential of microalgae for biogas and fertilizers production. This review covers recent investigations dealing with microalgae AD and highlights research opportunities and needs to support the development of this resource. Novel approaches to increase hydrolysis rate, the importance of the reactor design and the noteworthiness of the microbial anaerobic community are addressed. Finally, the integration of AD with microalgae processes and the potential of the carboxylate platform for chemicals and biofuels production are reviewed. Copyright © 2015 Elsevier Ltd. All rights reserved.

  11. European Socio-Economic Integration Challenges, Opportunities and Lessons Learned

    CERN Document Server

    Korres, George

    2013-01-01

    Economic integration is one of the most noteworthy issues in international economic policy at the end of the twentieth century. The recent examples of the European Union (EU) and the North American Free Trade Association (NAFTA) have raised important questions about the economic integration process and the possible establishment of economic unions in other parts of the world.  Against the backdrop of the financial crisis in Europe and prospects of increasing integration in Asia, this volume showcases research from an international array of researchers to provide a basic understanding of the current issues, problems, challenges, and opportunities for achieving integration, addressing both empirical and theoretical aspects of such topics as monetary union, social policy reform and social union, public finance and technology policy.  The chapters in Part 1 are focused primarily on economic issues, while Part 2 covers on social policy, the welfare state, and political reforms, with a particular emphasis on the ...

  12. 21st century challenges and opportunities for nuclear waste management

    International Nuclear Information System (INIS)

    McKinley, I.G.

    2009-01-01

    The technical arguments for massive expansion of nuclear power generation are convincing, but such a renaissance requires public acceptance. For diehard nuclear opponents, criticism now focuses on its Achilles heel - the unsolved (and often claimed to be insoluble) problem of disposal of the resultant long-lived waste. In fact, the geological disposal of nuclear waste can be managed safely with existing technology and should really be touted as one of the advantages of this option. Clearly, there is a major challenge in communicating disposal safety to key stakeholders in order to realise this benefit. Nevertheless, the growth of environmental concern about global warming and the present economic climate may present opportunities to initiate dialogue with relevant communities, allowing the attractions of hosting future disposal facilities to be seen. Rather than being the archetypal focus for NIMBY reactions, maybe within a few years we can look forward to growing competition to host geological repositories for radioactive waste.(Author)

  13. Spectroscopy with synchrotron radiation sources: challenges and opportunities

    International Nuclear Information System (INIS)

    Jagatap, B.N.

    2011-01-01

    Spectroscopy and energetics of atoms, molecules and cluster in ultra-violate (UV), vacuum ultra-violate (VUV) and soft X-ray region is one of the frontier topics of research today, These high energy photons allow us to prepare atomic and molecular systems in energy levels far away from their ground levels; the energy region that is characterized by the complex and highly degenerate energy level structure and multiple channels for reaction and energy dissipation. In this talk we provide a bird's eye view of the progress in this area, with a particular emphasis on spectroscopy research using Indian synchrotron sources. We shall also cover the avenues for collaborative research on Indus synchrotron sources, and the challenges and opportunities that await the Indian spectroscopy community

  14. Doomsday 2012 and Cosmophobia: Challenges and Opportunities for Science Communication

    Science.gov (United States)

    Fraknoi, A.; Larsen, K.; Mendez, B.; Morrison, D.; Van Stone, M.

    2013-04-01

    Hollywood movies, cable-channel documentaries, and countless books and websites have convinced a significant fraction of the U.S. public that some kind of catastrophe awaits us around the winter solstice of 2012, and that the cause of this catastrophe will be an astronomical or geophysical event. “Doomsday 2012” represents both a challenge and opportunity for science communication and education. This plenary panel discussed the basic ideas of the 2012 scenario and considered what is being done and what could be done to help the public understand what is real and what isn't. These lessons can be applied to future pseudoscientific predictions about the end of the world.

  15. Establishing a master's degree programme in bioinformatics: challenges and opportunities.

    Science.gov (United States)

    Sahinidis, N V; Harandi, M T; Heath, M T; Murphy, L; Snir, M; Wheeler, R P; Zukoski, C F

    2005-12-01

    The development of the Bioinformatics MS degree program at the University of Illinois, the challenges and opportunities associated with such a process, and the current structure of the program is described. This program has departed from earlier University practice in significant ways. Despite the existence of several interdisciplinary programs at the University, a few of which grant degrees, this is the first interdisciplinary program that grants degrees and formally recognises departmental specialisation areas. The program, which is not owned by any particular department but by the Graduate College itself, is operated in a franchise-like fashion via several departmental concentrations. With four different colleges and many more departments involved in establishing and operating the program, the logistics of the operation are of considerable complexity but result in significant interactions across the entire campus.

  16. Nano/microscale pyroelectric energy harvesting: challenges and opportunities

    Directory of Open Access Journals (Sweden)

    Devashish Lingam

    2013-12-01

    Full Text Available With the ever-growing demand for renewable energy sources, energy harvesting from natural resources has gained much attention. Energy sources such as heat and mechanical motion could be easily harvested based on pyroelectric, thermoelectric, and piezoelectric effects. The energy harvested from otherwise wasted energy in the environment can be utilized in self-powered micro and nano devices, and wearable electronics, which required only µW–mW power. This article reviews pyroelectric energy harvesting with an emphasis on recent developments in pyroelectric energy harvesting and devices at micro/nanoscale. Recent developments are presented and future challenges and opportunities for more efficient materials and devices with higher energy conversion efficiency are also discussed.

  17. E-LEARNING CHANGE MANAGEMENT: Challenges and opportunities

    Directory of Open Access Journals (Sweden)

    Alaattin PARLAKKILIC

    2013-10-01

    Full Text Available The role of e-learning technologies entirely depends on the acceptance and execution of required-change in the thinking and behaviour of the users of institutions. The research are constantly reporting that many e-learning projects are falling short of their objectives due to many reasons but on the top is the user resistance to change according to the digital requirements of new era. It is argued that the suitable way for change management in e-learning environment is the training and persuading of users with a view to enhance their digital literacy and thus gradually changing the users’ attitude in positive direction. This paper discusses change management in transition to e-learning system considering pedagogical, cost and technical implications. It also discusses challenges and opportunities for integrating these technologies in higher learning institutions with examples from Turkey GATA (Gülhane Askeri Tıp Akademisi-Gülhane Military Medical Academy.

  18. Research fields, challenges and opportunities in European oilseed crops breeding

    Directory of Open Access Journals (Sweden)

    Vincourt Patrick

    2014-11-01

    Full Text Available Due to the geographical specialization in oilseed world production, Europe has a major role to play in winter oilseed rape and sunflower breeding. Mainly based on the most recen t results, this review aims to identify the main research and breeding targets for these two crops, as seen through publications, with an attempt to suggest what are opportunities and challenges in these research fields. Growing a healthy and yielding crop remains the key driver for agronomic production. However sustainability and environmental profiles of the cultivar are now entering the field of play: The sustainability concern invested the field of resistance to diseases. Nitrogen use efficiency became an important target for Brassica napus, and crop resilience toward drought stresses is the way chosen in Helianthus annuus breeding for yield improvement. Significant advances are underway for quality traits, but the uncertainty on nutritional and industrial demand may explain why the product diversification remains low.

  19. Big biomedical data and cardiovascular disease research: opportunities and challenges.

    Science.gov (United States)

    Denaxas, Spiros C; Morley, Katherine I

    2015-07-01

    Electronic health records (EHRs), data generated and collected during normal clinical care, are increasingly being linked and used for translational cardiovascular disease research. Electronic health record data can be structured (e.g. coded diagnoses) or unstructured (e.g. clinical notes) and increasingly encapsulate medical imaging, genomic and patient-generated information. Large-scale EHR linkages enable researchers to conduct high-resolution observational and interventional clinical research at an unprecedented scale. A significant amount of preparatory work and research, however, is required to identify, obtain, and transform raw EHR data into research-ready variables that can be statistically analysed. This study critically reviews the opportunities and challenges that EHR data present in the field of cardiovascular disease clinical research and provides a series of recommendations for advancing and facilitating EHR research.

  20. Meta-synthesis of qualitative research: the challenges and opportunities.

    Science.gov (United States)

    Mohammed, Mohammed A; Moles, Rebekah J; Chen, Timothy F

    2016-06-01

    Synthesis of qualitative studies is an emerging area that has been gaining more interest as an important source of evidence for improving health care policy and practice. In the last decade there have been numerous attempts to develop methods of aggregating and synthesizing qualitative data. Although numerous empirical qualitative studies have been published about different aspects of health care research, to date, the aggregation and syntheses of these data has not been commonly reported, particularly in pharmacy practice related research. This paper describes different methods of conducting meta-synthesis and provides an overview of selected common methods. The paper also emphasizes the challenges and opportunities associated with conducting meta-synthesis and highlights the importance of meta-synthesis in informing practice, policy and research.

  1. Challenges and opportunities for improved understanding of regional climate dynamics

    Science.gov (United States)

    Collins, Matthew; Minobe, Shoshiro; Barreiro, Marcelo; Bordoni, Simona; Kaspi, Yohai; Kuwano-Yoshida, Akira; Keenlyside, Noel; Manzini, Elisa; O'Reilly, Christopher H.; Sutton, Rowan; Xie, Shang-Ping; Zolina, Olga

    2018-01-01

    Dynamical processes in the atmosphere and ocean are central to determining the large-scale drivers of regional climate change, yet their predictive understanding is poor. Here, we identify three frontline challenges in climate dynamics where significant progress can be made to inform adaptation: response of storms, blocks and jet streams to external forcing; basin-to-basin and tropical-extratropical teleconnections; and the development of non-linear predictive theory. We highlight opportunities and techniques for making immediate progress in these areas, which critically involve the development of high-resolution coupled model simulations, partial coupling or pacemaker experiments, as well as the development and use of dynamical metrics and exploitation of hierarchies of models.

  2. Opportunities and challenges working in the former Soviet Union

    International Nuclear Information System (INIS)

    Gueritte, C.

    1992-01-01

    The recent opening up of the Commonwealth of Independent States (CIS) to foreign companies has provided oil and gas companies with the opportunity to enter into business relationships with CIS partners to develop that region's vast hydrocarbon resources. The CIS is experiencing a decline in production due to major declines in output from the giant oil fields, lack of equipment and technology, limited exploration investment, environmental problems, inadequate pricing structures, and social instability. Gas production, although rising up to the end of 1990, is threatened by emergence of technological problems in maintaining productivity of the main gas fields. The challenges for carrying out business in the CIS are outlined, including technical aspects, business mentality, economic approach, political organization, legal and fiscal stability, and financing. Experiences in operating in the CIS are illustrated from the viewpoint of the French company Total Exploration and Production, which is engaged in enhanced recovery operations and development of fields in joint ventures. 5 figs., 2 tabs

  3. Cold Plasmas for Biofilm Control: Opportunities and Challenges.

    Science.gov (United States)

    Gilmore, Brendan F; Flynn, Padrig B; O'Brien, Séamus; Hickok, Noreen; Freeman, Theresa; Bourke, Paula

    2018-06-01

    Bacterial biofilm infections account for a major proportion of chronic and medical device associated infections in humans, yet our ability to control them is compromised by their inherent tolerance to antimicrobial agents. Cold atmospheric plasma (CAP) represents a promising therapeutic option. CAP treatment of microbial biofilms represents the convergence of two complex phenomena: the production of a chemically diverse mixture of reactive species and intermediates, and their interaction with a heterogeneous 3D interface created by the biofilm extracellular polymeric matrix. Therefore, understanding these interactions and physiological responses to CAP exposure are central to effective management of infectious biofilms. We review the unique opportunities and challenges for translating CAP to the management of biofilms. Copyright © 2018. Published by Elsevier Ltd.

  4. Mobile Network Data for Public-Health: Opportunities and Challenges

    Directory of Open Access Journals (Sweden)

    Nuria eOliver

    2015-08-01

    Full Text Available The ubiquity of mobile phones worldwide is generating an unprecedented amount of human behavioral data both at an individual and aggregated levels. The study of this data as a rich source of information about human behavior emerged almost a decade ago. Since then it has grown into a fertile area of research named computational social sciences with a wide variety of applications in different fields such as social networks, urban and transport planning, economic development, emergency relief and, recently, public health. In this paper we briefly describe the state of the art on using mobile phone data for public health, and present the opportunities and challenges that this kind of data presents for public health.

  5. Mobile Network Data for Public Health: Opportunities and Challenges

    Science.gov (United States)

    Oliver, Nuria; Matic, Aleksandar; Frias-Martinez, Enrique

    2015-01-01

    The ubiquity of mobile phones worldwide is generating an unprecedented amount of human behavioral data both at an individual and aggregated levels. The study of this data as a rich source of information about human behavior emerged almost a decade ago. Since then, it has grown into a fertile area of research named computational social sciences with a wide variety of applications in different fields such as social networks, urban and transport planning, economic development, emergency relief, and, recently, public health. In this paper, we briefly describe the state of the art on using mobile phone data for public health, and present the opportunities and challenges that this kind of data presents for public health. PMID:26301211

  6. [Precision medicine: new opportunities and challenges for molecular epidemiology].

    Science.gov (United States)

    Song, Jing; Hu, Yonghua

    2016-04-01

    Since the completion of the Human Genome Project in 2003 and the announcement of the Precision Medicine Initiative by U.S. President Barack Obama in January 2015, human beings have initially completed the " three steps" of " genomics to biology, genomics to health as well as genomics to society". As a new inter-discipline, the emergence and development of precision medicine have relied on the support and promotion from biological science, basic medicine, clinical medicine, epidemiology, statistics, sociology and information science, etc. Meanwhile, molecular epidemiology is considered to be the core power to promote precision medical as a cross discipline of epidemiology and molecular biology. This article is based on the characteristics and research progress of medicine and molecular epidemiology respectively, focusing on the contribution and significance of molecular epidemiology to precision medicine, and exploring the possible opportunities and challenges in the future.

  7. The Data Issue: Opportunities and Challenges for Scientific Publishers

    Science.gov (United States)

    Murphy, F.; Irving, D. H.

    2011-12-01

    Using the recent report for the 'Opportunities in Data Exchange' Project produced by - and for - researchers, libraries/data centres and publishers (and which is based on a broad range of studies, questionnaires and evidence) we have defined current practices and expectations, and the gaps and dilemmas involved in producing data and datasets, and then analysed their relationship to formal publications. As a result, we identified potential opportunities to evolve scientific insights to be more useful and re-useful: with consequent implications for custodianship and long-term data management. We also defined a number of key incentives and barriers towards achieving these objectives. As a case study, the earth and environmental sciences have come under particularly close scrutiny with respect to data-ownership and -sharing arrangements, sometimes with damaging results to the discipline's reputation. These issues, along with considerable technological challenges, have to be handled effectively in order to best support all the users along the data chain. To that end, we show that key stakeholders - among them scientific publishers - need to have a clear idea of how to progress data-intensive derived information, which we demonstrate is often not the case. Towards bridging this knowledge gap, we have compiled a roadmap of next steps and key issues to be acknowledged and addressed by the scientific publishing community. These include: engaging directly with researchers, policy-makers, funding bodies and direct competitors to build innovative partnerships and enhance impact; providing technological and training investment and developing alongside the emerging discipline of 'data scientist': the 'data publisher'. This individual/company will need to combine a close understanding of researchers' priorities, together with market, legal and technical opportunities and restrictions.

  8. Harnessing the market: The opportunities and challenges of privatization

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-01-01

    The decision to privatize comes from a policy determination that the Government no longer needs particular assets or no longer needs to be in control of all the means by which products or services are obtained or delivered. Most broadly defined, privatization substitutes, in whole or in part, private market mechanisms for the traditional Government role as employer, financier, owner, operator, and/or regulator of a product or service. This definition admits a wide variety of actions, from innovative contractual arrangements to outright divestiture of activities or assets. But all of these actions share common objectives: to remove the agency from those activities that are not inherently governmental functions or core business lines; to improve the management of remaining activities; to reduce the costs of doing business; and to shift greater performance and financial risk to the private sector. This report by the Privatization Working Group provides an indepth analysis of the major issues that surround privatization within the Department of Energy (DOE). The report divides privatization initiatives at the DOE into three major types: divestiture of functions, contracting out, and asset transfers. It includes the results of a survey of the entire DOE system that identifies more than 200 potential privatization opportunities. The report also includes 13 case studies that explore actual DOE privatization efforts over the past 2 years. Additionally, it summarizes the key legal authorities that govern each of the three types of privatization opportunities in the DOE. The report makes a series of recommendations and outlines accompanying actions that will help the DOE seize the opportunities presented by privatization and confront its challenges.

  9. Mathematics and biology: The interface, challenges and opportunities

    Energy Technology Data Exchange (ETDEWEB)

    Levin, S.A. (ed.) (Cornell Univ., Ithaca, NY (United States))

    1992-06-01

    The interface between mathematics and biology has long been a rich area of research, with mutual benefit to each supporting discipline. Traditional areas of investigation, such as population genetics, ecology, neurobiology, and 3-D reconstructions, have flourished, despite a rather meager environment for the funding of such work. In the past twenty years, the kind and scope of such interactions between mathematicians and biologists have changed dramatically, reaching out to encompass areas of both biology and mathematics that previously had not benefited. At the same time, with the closer integration of theory and experiment, and the increased reliance on high-speed computation, the costs of such research grew, though not the opportunities for funding. The perception became reinforced, both within the research community and at funding agencies, that although these interactions were expanding, they were not doing so at the rate necessary to meet the opportunities and needs. A workshop was held in Washington, DC, between April 28 and May 3, 1990 which drew together a broadly based group of researchers to synthesize conclusions from a group of working papers and extended discussions. The result is the report presented here, which we hope will provide a guide and stimulus to research in mathematical and computational biology for at least the next decade. The report identifies a number of grand challenges, representing a broad consensus among the participants.

  10. Machine Learning for Precision Psychiatry: Opportunities and Challenges.

    Science.gov (United States)

    Bzdok, Danilo; Meyer-Lindenberg, Andreas

    2018-03-01

    The nature of mental illness remains a conundrum. Traditional disease categories are increasingly suspected to misrepresent the causes underlying mental disturbance. Yet psychiatrists and investigators now have an unprecedented opportunity to benefit from complex patterns in brain, behavior, and genes using methods from machine learning (e.g., support vector machines, modern neural-network algorithms, cross-validation procedures). Combining these analysis techniques with a wealth of data from consortia and repositories has the potential to advance a biologically grounded redefinition of major psychiatric disorders. Increasing evidence suggests that data-derived subgroups of psychiatric patients can better predict treatment outcomes than DSM/ICD diagnoses can. In a new era of evidence-based psychiatry tailored to single patients, objectively measurable endophenotypes could allow for early disease detection, individualized treatment selection, and dosage adjustment to reduce the burden of disease. This primer aims to introduce clinicians and researchers to the opportunities and challenges in bringing machine intelligence into psychiatric practice. Copyright © 2017 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.

  11. Chemical engineering challenges and investment opportunities in sustainable energy.

    Science.gov (United States)

    Heller, Adam

    2008-01-01

    The chemical and energy industries are transforming as they adjust to the new era of high-priced petroleum and severe global warming. As a result of the transformation, engineering challenges and investment opportunities abound. Rapid evolution and fast growth are expected in cathode and anode materials as well as polymeric electrolytes for vehicular batteries and in high-performance polymer-ceramic composites for wind turbines, fuel-efficient aircraft, and lighter and safer cars. Unique process-engineering opportunities exist in sand-oil, coal, and possibly also shale liquefaction to produce transportation fuel; and also in genetic engineering of photosynthesizing plants and other organisms for their processing into high-performance biodegradable polymers and high-value-added environmentally friendly chemicals. Also, research on the feasibility of mitigation of global warming through enhancement of CO(2) uptake by the southern oceans by fertilization with trace amounts of iron is progressing. Because chemical engineers are uniquely well trained in mathematical modeling of mass transport, flow, and mixing, and also in cost analysis, they are likely to join the oceanographers and marine biologists in this important endeavor.

  12. Natural capital and bioeconomy: challenges and opportunities for forestry

    Directory of Open Access Journals (Sweden)

    Marco Marchetti

    2015-01-01

    Full Text Available Over the last decades, the stock of natural capital has been globally reduced by human-induced effects such as climate change, and land use and cover modifications. In particular, the continuous flow of goods and services from ecosystems to people is currently under threat if the current human activities still remain unsustainable. The recent bioeconomy strategy is an important opportunity to halt the loss of biodiversity and the reduction of services provision, from global to local scale. In this framework, forest sector plays a fundamental role in further enhancing the sustainable development and the green growth in degraded environments, such as marginal and rural areas. This paper provides an overview of the bioeconomy-based natural resources management (with a focus on forest ecosystems, by analyzing the related challenges and opportunities, from international to national perspective, as in Italy. At first, the role of forest sector in addressing the purposes of green growth is analyzed. Secondly, the most suitable tools to monitor and assess natural capital changes are described. Finally, the most important research contributions within the bioeconomy context are reported. To create the suitable conditions for bioeconomy and green growth, the following insights have to be denoted: (i a deeper understanding of natural capital and related changes; (ii the improvement of public participation in decision-making processes, especially at landscape scale; (iii the effective integration of ecological, socio-cultural, and economic dimensions while managing natural resources.

  13. The process of developing audiovisual patient information: challenges and opportunities.

    Science.gov (United States)

    Hutchison, Catherine; McCreaddie, May

    2007-11-01

    The aim of this project was to produce audiovisual patient information, which was user friendly and fit for purpose. The purpose of the audiovisual patient information is to inform patients about randomized controlled trials, as a supplement to their trial-specific written information sheet. Audiovisual patient information is known to be an effective way of informing patients about treatment. User involvement is also recognized as being important in the development of service provision. The aim of this paper is (i) to describe and discuss the process of developing the audiovisual patient information and (ii) to highlight the challenges and opportunities, thereby identifying implications for practice. A future study will test the effectiveness of the audiovisual patient information in the cancer clinical trial setting. An advisory group was set up to oversee the project and provide guidance in relation to information content, level and delivery. An expert panel of two patients provided additional guidance and a dedicated operational team dealt with the logistics of the project including: ethics; finance; scriptwriting; filming; editing and intellectual property rights. Challenges included the limitations of filming in a busy clinical environment, restricted technical and financial resources, ethical needs and issues around copyright. There were, however, substantial opportunities that included utilizing creative skills, meaningfully involving patients, teamworking and mutual appreciation of clinical, multidisciplinary and technical expertise. Developing audiovisual patient information is an important area for nurses to be involved with. However, this must be performed within the context of the multiprofessional team. Teamworking, including patient involvement, is crucial as a wide variety of expertise is required. Many aspects of the process are transferable and will provide information and guidance for nurses, regardless of specialty, considering developing this

  14. Opportunities and challenges in promoting youth entrepreneurship in Montenegro

    Directory of Open Access Journals (Sweden)

    Vesna Karadzic

    2015-12-01

    Full Text Available Purpose – The purpose of this paper is to examine the opportunities and challenges that youth entrepreneurs are facing in Montenegro, considering all aspects of youth participation in the development of the country. A quality research of several successful young entrepreneurs is presented. Design/methodology/approach – Several successful young entrepreneurs were interviewed. The principles of case study design and method were followed. Data collection involved both macro and micro level analysis of interviews and direct observation. Findings – The analysis shows that although in the areas of youth participation, significant progress has been made in the last several years, youth entrepreneurship programme in Montenegro is still in its early stages of development and needs strong sustainable commitment, assuring the development and efficient functioning of various youth participation mechanisms at the local, regional and national level. It is also essential to continue to standardize and support youth work, youth information and non-formal business education of young people. Surveys show that young people in Montenegro believe they have much to offer and can significantly contribute to all areas of the society’s development. However, their potential remains greatly untapped due to certain obstacles that they face. There are needs for encouraging programs to inform youth about the value of their participation in all aspects of society. Research limitations/implications – The main limitations were access to a greater number of successful young entrepreneurs making the analysis more descriptive and conclusive. Originality/value – The paper supports understanding of the complex employment challenges and opportunities facing youth and stimulates discussion on how to address this key development issue.

  15. Opportunities and challenges of nanotechnology in the green economy.

    Science.gov (United States)

    Iavicoli, Ivo; Leso, Veruscka; Ricciardi, Walter; Hodson, Laura L; Hoover, Mark D

    2014-10-07

    In a world of finite resources and ecosystem capacity, the prevailing model of economic growth, founded on ever-increasing consumption of resources and emission pollutants, cannot be sustained any longer. In this context, the "green economy" concept has offered the opportunity to change the way that society manages the interaction of the environmental and economic domains. To enable society to build and sustain a green economy, the associated concept of "green nanotechnology" aims to exploit nano-innovations in materials science and engineering to generate products and processes that are energy efficient as well as economically and environmentally sustainable. These applications are expected to impact a large range of economic sectors, such as energy production and storage, clean up-technologies, as well as construction and related infrastructure industries. These solutions may offer the opportunities to reduce pressure on raw materials trading on renewable energy, to improve power delivery systems to be more reliable, efficient and safe as well as to use unconventional water sources or nano-enabled construction products therefore providing better ecosystem and livelihood conditions.However, the benefits of incorporating nanomaterials in green products and processes may bring challenges with them for environmental, health and safety risks, ethical and social issues, as well as uncertainty concerning market and consumer acceptance. Therefore, our aim is to examine the relationships among guiding principles for a green economy and opportunities for introducing nano-applications in this field as well as to critically analyze their practical challenges, especially related to the impact that they may have on the health and safety of workers involved in this innovative sector. These are principally due to the not fully known nanomaterial hazardous properties, as well as to the difficulties in characterizing exposure and defining emerging risks for the workforce

  16. Patient monitoring in mobile health: opportunities and challenges.

    Science.gov (United States)

    Mohammadzadeh, Niloofar; Safdari, Reza

    2014-01-01

    In most countries chronic diseases lead to high health care costs and reduced productivity of people in society. The best way to reduce costs of health sector and increase the empowerment of people is prevention of chronic diseases and appropriate health activities management through monitoring of patients. To enjoy the full benefits of E-health, making use of methods and modern technologies is very important. This literature review articles were searched with keywords like Patient monitoring, Mobile Health, and Chronic Disease in Science Direct, Google Scholar and Pub Med databases without regard to the year of publications. Applying remote medical diagnosis and monitoring system based on mobile health systems can help significantly to reduce health care costs, correct performance management particularly in chronic disease management. Also some challenges are in patient monitoring in general and specific aspects like threats to confidentiality and privacy, technology acceptance in general and lack of system interoperability with electronic health records and other IT tools, decrease in face to face communication between doctor and patient, sudden interruptions of telecommunication networks, and device and sensor type in specific aspect. It is obvious identifying the opportunities and challenges of mobile technology and reducing barriers, strengthening the positive points will have a significant role in the appropriate planning and promoting the achievements of the health care systems based on mobile and helps to design a roadmap for improvement of mobile health.

  17. Sustainable development: challenges and opportunities for the natural sciences (Invited)

    Science.gov (United States)

    Mutter, J. C.; Fishman, R.; Anttila-Hughes, J. K.; Hsiang, S. M.

    2009-12-01

    The challenges of sustainable development -- equitably improving global human welfare while ensuring that the environment is preserved for future generations - demand research at the nexus of the social and natural sciences. Massive and inevitable changes in climate, ecosystem functions, and human interaction with the environment will perturb societies throughout the world in different ways over the coming century. The changes faced by poor societies and their ability to cope differs markedly from those that face the richest. Yet in all regions the dynamic interaction of social and natural drivers will govern the prospects for human welfare and its improvement. Developing an understanding of these phenomena will require field research together with analytical and modeling capabilities that couple physical and social phenomena, allowing feedback between the two to manifest and permit forecasting over long time scales. Heterogeneous income and population growth further complicate this need through their consequences for food security, migration, resource allocation, and conflict. In this contribution, we identify some key concepts of sustainable development, open research questions and outline how scientific research might engage this emerging discipline. Using recent examples of interaction, we discuss the opportunities and challenges facing the further development of this dialogue.

  18. Synthetic Biology of Cyanobacteria: Unique Challenges and Opportunities

    Directory of Open Access Journals (Sweden)

    Bertram M Berla

    2013-08-01

    Full Text Available Photosynthetic organisms, and especially cyanobacteria, hold great promise as sources of renewably-produced fuels, bulk and specialty chemicals, and nutritional products. Synthetic biology tools can help unlock cyanobacteria’s potential for these functions, but unfortunately tool development for these organisms has lagged behind that for S. cerevisiae and E. coli. While these organisms may in many cases be more difficult to work with as ‘chassis’ strains for synthetic biology than certain heterotrophs, the unique advantages of autotrophs in biotechnology applications as well as the scientific importance of improved understanding of photosynthesis warrant the development of these systems into something akin to a ‘green E. coli’. In this review, we highlight unique challenges and opportunities for development of synthetic biology approaches in cyanobacteria. We review classical and recently developed methods for constructing targeted mutants in various cyanobacterial strains, and offer perspective on what genetic tools might most greatly expand the ability to engineer new functions in such strains. Similarly, we review what genetic parts are most needed for the development of cyanobacterial synthetic biology. Finally, we highlight recent methods to construct genome-scale models of cyanobacterial metabolism and to use those models to measure properties of autotrophic metabolism. Throughout this paper, we discuss some of the unique challenges of a diurnal, autotrophic lifestyle along with how the development of synthetic biology and biotechnology in cyanobacteria must fit within those constraints.

  19. Getting Australia more active: challenges and opportunities for health promotion.

    Science.gov (United States)

    Hills, A P; Street, S J; Harris, N

    2014-04-01

    A growing body of evidence demonstrates that regular physical activity promotes health and assists in the prevention of non-communicable diseases but this is presently curtailed by low and unhealthy participation rates in Australia and comparable industrialised countries. Compounding the problem is knowledge that physical inactivity is independently associated with poor health outcomes. Despite physical activity being described as public health's 'best bet' or 'best buy', motivating individuals and groups to adopt and maintain physical activity continues to be a major challenge for health professionals. Global advocacy for prevention efforts must be operationalised through national to local strategies to promote and support physical activity in multiple settings including the home, schools and workplace. The Australian health promotion community has and continues to play a leadership role in physical activity promotion. However, there is an urgent need to continue to promote the importance of physical activity, along with its pivotal role in the prevention of non-communicable diseases, alongside related agendas including healthy diets, tobacco control and environmental sustainability. This commentary overviews the contemporary status of physical activity promotion in Australia and identifies key challenges and opportunities moving forward.

  20. Unpacking the Pacific Urban Agenda: Resilience Challenges and Opportunities

    Directory of Open Access Journals (Sweden)

    Gabriel Luke Kiddle

    2017-10-01

    Full Text Available Pacific Island Countries (PICs are often cited as being the most vulnerable to the future impacts of a changing climate. Furthermore, being located in the ‘Pacific Rim of Fire’, PICs have long been exposed to the impacts of a range of natural and climate-related extreme events—such as earthquakes and cyclones—and are considered to be amongst the most vulnerable countries to natural disasters. The physical vulnerability of Pacific towns and cities is further exaggerated by development deficits, geographical isolation, weak governance, and complex issues of land tenure. This paper, based on substantive project experience in the Pacific region by each of the authors, reviews the resilience challenges facing Melanesian cities in the context of rapid urbanization and global environmental change. It then sets this in the context of the global ‘New Urban Agenda’ which was launched at Habitat III in Quito at the end of 2016, setting out the critical implementation challenges and opportunities for enhancing urban resilience in the Pacific.

  1. Tsetse and trypanosomosis in Africa: the challenges, the opportunities.

    Science.gov (United States)

    Ilemobade, A A

    2009-03-01

    Tsetse-fly and the disease it transmits, trypanosomosis, remain an enormous disease challenge in the 37 countries of sub-Saharan Africa where the impact continues to be manifest in disease burden, increased level of poverty and decreased agricultural productivity. The impact also extends over an estimated 10 million km2 (a third of the African continent) of land area, a third of which contains some well-watered part of the continent, thus denying humans and livestock of potentially rich arable and pastureland. The disease is a threat to an estimated 50 million people and 48 million cattle with estimated annual losses in cattle production alone of 1-1.2 billion US$. These losses are due to stock mortality and depressed productivity, which may be of meat, milk, reproduction or traction. Beyond its direct effects on humans and livestock is its impact on African agriculture and the livelihood of the rural population in the affected countries: the fly and the disease influence where people decide to live, how they manage their livestock, and the intensity and the mix of crop agriculture. The combined effects result in changes in land use and environment which may, in turn, affect human welfare and increase the vulnerability of agricultural activity. Trypanosomosis is, therefore, both a public health and an agricultural development constraint. The challenges that the elimination or control of tsetse fly and trypanosomosis pose as well as the opportunities to develop appropriate intervention technologies are discussed in this presentation.

  2. Unsanctifying the sanctuary: challenges and opportunities with brain metastases.

    Science.gov (United States)

    Puhalla, Shannon; Elmquist, William; Freyer, David; Kleinberg, Lawrence; Adkins, Chris; Lockman, Paul; McGregor, John; Muldoon, Leslie; Nesbit, Gary; Peereboom, David; Smith, Quentin; Walker, Sara; Neuwelt, Edward

    2015-05-01

    While the use of targeted therapies, particularly radiosurgery, has broadened therapeutic options for CNS metastases, patients respond minimally and prognosis remains poor. The inability of many systemic chemotherapeutic agents to penetrate the blood-brain barrier (BBB) has limited their use and allowed brain metastases to become a burgeoning clinical challenge. Adequate preclinical models that appropriately mimic the metastatic process, the BBB, and blood-tumor barriers (BTB) are needed to better evaluate therapies that have the ability to enhance delivery through or penetrate into these barriers and to understand the mechanisms of resistance to therapy. The heterogeneity among and within different solid tumors and subtypes of solid tumors further adds to the difficulties in determining the most appropriate treatment approaches and methods of laboratory and clinical studies. This review article discusses therapies focused on prevention and treatment of CNS metastases, particularly regarding the BBB, and the challenges and opportunities these therapies present. © The Author(s) 2015. Published by Oxford University Press on behalf of the Society for Neuro-Oncology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  3. BIGCHEM: Challenges and Opportunities for Big Data Analysis in Chemistry.

    Science.gov (United States)

    Tetko, Igor V; Engkvist, Ola; Koch, Uwe; Reymond, Jean-Louis; Chen, Hongming

    2016-12-01

    The increasing volume of biomedical data in chemistry and life sciences requires the development of new methods and approaches for their handling. Here, we briefly discuss some challenges and opportunities of this fast growing area of research with a focus on those to be addressed within the BIGCHEM project. The article starts with a brief description of some available resources for "Big Data" in chemistry and a discussion of the importance of data quality. We then discuss challenges with visualization of millions of compounds by combining chemical and biological data, the expectations from mining the "Big Data" using advanced machine-learning methods, and their applications in polypharmacology prediction and target de-convolution in phenotypic screening. We show that the efficient exploration of billions of molecules requires the development of smart strategies. We also address the issue of secure information sharing without disclosing chemical structures, which is critical to enable bi-party or multi-party data sharing. Data sharing is important in the context of the recent trend of "open innovation" in pharmaceutical industry, which has led to not only more information sharing among academics and pharma industries but also the so-called "precompetitive" collaboration between pharma companies. At the end we highlight the importance of education in "Big Data" for further progress of this area. © 2016 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA.

  4. Nanotechnology Applications in Functional Foods; Opportunities and Challenges.

    Science.gov (United States)

    Singh, Harjinder

    2016-03-01

    Increasing knowledge on the link between diet and human health has generated a lot of interest in the development of functional foods. However, several challenges, including discovering of beneficial compounds, establishing optimal intake levels, and developing adequate food delivering matrix and product formulations, need to be addressed. A number of new processes and materials derived from nanotechnology have the potential to provide new solutions in many of these fronts. Nanotechnology is concerned with the manipulation of materials at the atomic and molecular scales to create structures that are less than 100 nm in size in one dimension. By carefully choosing the molecular components, it seems possible to design particles with different surface properties. Several food-based nanodelivery vehicles, such as protein-polysaccharide coacervates, multiple emulsions, liposomes and cochleates have been developed on a laboratory scale, but there have been very limited applications in real food systems. There are also public concerns about potential negative effects of nanotechnology-based delivery systems on human health. This paper provides an overview of the new opportunities and challenges for nanotechnology-based systems in future functional food development.

  5. Wind power and community benefits: Challenges and opportunities

    International Nuclear Information System (INIS)

    Aitken, Mhairi

    2010-01-01

    A challenge relating to the development of renewable energy in the UK concerns how large companies can foster positive relationships with local communities. The concepts of 'trust' and 'fairness' are central to debates around proposed renewable energy developments, however, these concepts are complex, ambiguous and interrelated. In the UK the provision of community benefits stemming from the development of renewable energy projects remains a voluntary activity. This paper presents the findings of a case study of one wind power development and how community benefits associated with this were perceived by the local community throughout various stages of the case study (notably during planning, construction and operation). The case study highlights the challenging nature of community benefits from wind power developments. Important decisions regarding who the relevant local community is or what form community benefits should take present opportunities for disagreement between conflicting interests. It is argued that institutionalised guidance would serve a number of worthwhile purposes. Firstly, they would provide greater clarity. Secondly, they would give developers greater confidence to discuss the community benefits package in the early planning stages, and thirdly, they would reduce the likelihood of community benefits being perceived as bribes.

  6. Opportunities and challenges for emerging nuclear power states

    International Nuclear Information System (INIS)

    Nkong-Njock, V.; Facer, R.I.; Boussaha, A.

    2009-01-01

    Energy and reliable access to energy sources are essential to economic and social development and improved quality of life. However, limited access to modern energy still remains one of the major constraints to socio-economic development in many parts in the world. On the other hand, energy production, distribution and consumption may have many adverse effects on the local, regional and global environment including climate change. Production and consumption of fossil fuels constitutes the main source of greenhouse gas emissions (GHGs). Cleaner and affordable energy systems are therefore needed to address all of these effects and to contribute to environmental sustainability. Nuclear power is a proven technology with virtually no greenhouse gas emissions or emission of pollutants, and therefore is expected to play an increasing role in meeting this rapidly growing global requirements for clean and economic electricity. But, it is known that challenges and opportunities are polarities, and as opposite poles of the magnet, they do not exist separately. An opportunity for some can be a challenge for others, or a challenge today can become an opportunity tomorrow. The potential growth of nuclear power has increased, in some quarters, concern that nonproliferation should be given sufficient attention. In particular, since introduction of many new power reactors will require increased uranium enrichment services, with the potential proliferation risk of adding enrichment facilities in new countries. This has urged the international community to strongly support the development of safeguarded and well-regulated nuclear power around the world, with the aim to ensure that nuclear power is deployed through a commitment to the highest possible standards of nuclear safety, security, and non-proliferation. The keys issues and trends for nuclear power expansion include therefore problems related to (i) safety, security and reliability, (ii) public perception and acceptance, (iii

  7. The culture of excellence. Challenges and opportunities during changing times

    Directory of Open Access Journals (Sweden)

    Suciu Marta-Christina

    2017-07-01

    Full Text Available The main goal of the paper is to highlight the importance of supporting the promotion of the culture of excellence among people involved in a way or another in contemporary business. In order to support business excellence, the culture of excellence have to empower and engage all the people within an organization to think out of the box in a modern vision suitable to the challenging and changing times we are facing now. All over the world, in the most competitive countries, regions and sectors of activities there is a paradigmatic change of business strategies and policies oriented more and more towards performance and excellence. The paper highlights the importance of promoting the culture of excellence in the contemporary changing business environment. It suggests an important shift from a perspective that focuses on the so called ‘hero of excellence’ towards promoting the culture of excellence among the whole organization. Within modern business, in order to face challenges of the changing times and to explore their opportunities all the people from an organization are considered to manifest as ‘heroes of excellence’ by co-creating and co-working together within creative and innovative teams. They have to contribute and to participate actively to assure, preserve and develop the competitiveness and well being of the whole organization. The paper supports a holistic, cross disciplinary and integrated vision. It is structured into three parts including: a brief literature review based on an overview of the current state of the literature dedicated to the topic of culture of excellence (part 1; presentation of the main steps of the process of building a sustainable high performance organization (part 2; a brief presentation of examples of best practice and case studied identified internationally (part 3; conclusions that highlight the importance of culture of excellence in changing and challenging times.

  8. The challenges and opportunities in cumulative effects assessment

    Energy Technology Data Exchange (ETDEWEB)

    Foley, Melissa M., E-mail: mfoley@usgs.gov [U.S. Geological Survey, Pacific Coastal and Marine Science Center, 400 Natural Bridges, Dr., Santa Cruz, CA 95060 (United States); Center for Ocean Solutions, Stanford University, 99 Pacific St., Monterey, CA 93940 (United States); Mease, Lindley A., E-mail: lamease@stanford.edu [Center for Ocean Solutions, Stanford University, 473 Via Ortega, Stanford, CA 94305 (United States); Martone, Rebecca G., E-mail: rmartone@stanford.edu [Center for Ocean Solutions, Stanford University, 99 Pacific St., Monterey, CA 93940 (United States); Prahler, Erin E. [Center for Ocean Solutions, Stanford University, 473 Via Ortega, Stanford, CA 94305 (United States); Morrison, Tiffany H., E-mail: tiffany.morrison@jcu.edu.au [ARC Centre of Excellence for Coral Reef Studies, James Cook University, Townsville, QLD, 4811 (Australia); Murray, Cathryn Clarke, E-mail: cmurray@pices.int [WWF-Canada, 409 Granville Street, Suite 1588, Vancouver, BC V6C 1T2 (Canada); Wojcik, Deborah, E-mail: deb.wojcik@duke.edu [Nicholas School for the Environment, Duke University, 9 Circuit Dr., Durham, NC 27708 (United States)

    2017-01-15

    The cumulative effects of increasing human use of the ocean and coastal zone have contributed to a rapid decline in ocean and coastal resources. As a result, scientists are investigating how multiple, overlapping stressors accumulate in the environment and impact ecosystems. These investigations are the foundation for the development of new tools that account for and predict cumulative effects in order to more adequately prevent or mitigate negative effects. Despite scientific advances, legal requirements, and management guidance, those who conduct assessments—including resource managers, agency staff, and consultants—continue to struggle to thoroughly evaluate cumulative effects, particularly as part of the environmental assessment process. Even though 45 years have passed since the United States National Environmental Policy Act was enacted, which set a precedent for environmental assessment around the world, defining impacts, baseline, scale, and significance are still major challenges associated with assessing cumulative effects. In addition, we know little about how practitioners tackle these challenges or how assessment aligns with current scientific recommendations. To shed more light on these challenges and gaps, we undertook a comparative study on how cumulative effects assessment (CEA) is conducted by practitioners operating under some of the most well-developed environmental laws around the globe: California, USA; British Columbia, Canada; Queensland, Australia; and New Zealand. We found that practitioners used a broad and varied definition of impact for CEA, which led to differences in how baseline, scale, and significance were determined. We also found that practice and science are not closely aligned and, as such, we highlight opportunities for managers, policy makers, practitioners, and scientists to improve environmental assessment.

  9. The challenges and opportunities in cumulative effects assessment

    International Nuclear Information System (INIS)

    Foley, Melissa M.; Mease, Lindley A.; Martone, Rebecca G.; Prahler, Erin E.; Morrison, Tiffany H.; Murray, Cathryn Clarke; Wojcik, Deborah

    2017-01-01

    The cumulative effects of increasing human use of the ocean and coastal zone have contributed to a rapid decline in ocean and coastal resources. As a result, scientists are investigating how multiple, overlapping stressors accumulate in the environment and impact ecosystems. These investigations are the foundation for the development of new tools that account for and predict cumulative effects in order to more adequately prevent or mitigate negative effects. Despite scientific advances, legal requirements, and management guidance, those who conduct assessments—including resource managers, agency staff, and consultants—continue to struggle to thoroughly evaluate cumulative effects, particularly as part of the environmental assessment process. Even though 45 years have passed since the United States National Environmental Policy Act was enacted, which set a precedent for environmental assessment around the world, defining impacts, baseline, scale, and significance are still major challenges associated with assessing cumulative effects. In addition, we know little about how practitioners tackle these challenges or how assessment aligns with current scientific recommendations. To shed more light on these challenges and gaps, we undertook a comparative study on how cumulative effects assessment (CEA) is conducted by practitioners operating under some of the most well-developed environmental laws around the globe: California, USA; British Columbia, Canada; Queensland, Australia; and New Zealand. We found that practitioners used a broad and varied definition of impact for CEA, which led to differences in how baseline, scale, and significance were determined. We also found that practice and science are not closely aligned and, as such, we highlight opportunities for managers, policy makers, practitioners, and scientists to improve environmental assessment.

  10. The challenges and opportunities in cumulative effects assessment

    Science.gov (United States)

    Foley, Melissa M.; Mease, Lindley A; Martone, Rebecca G; Prahler, Erin E; Morrison, Tiffany H; Clarke Murray, Cathryn; Wojcik, Deborah

    2016-01-01

    The cumulative effects of increasing human use of the ocean and coastal zone have contributed to a rapid decline in ocean and coastal resources. As a result, scientists are investigating how multiple, overlapping stressors accumulate in the environment and impact ecosystems. These investigations are the foundation for the development of new tools that account for and predict cumulative effects in order to more adequately prevent or mitigate negative effects. Despite scientific advances, legal requirements, and management guidance, those who conduct assessments—including resource managers, agency staff, and consultants—continue to struggle to thoroughly evaluate cumulative effects, particularly as part of the environmental assessment process. Even though 45 years have passed since the United States National Environmental Policy Act was enacted, which set a precedent for environmental assessment around the world, defining impacts, baseline, scale, and significance are still major challenges associated with assessing cumulative effects. In addition, we know little about how practitioners tackle these challenges or how assessment aligns with current scientific recommendations. To shed more light on these challenges and gaps, we undertook a comparative study on how cumulative effects assessment (CEA) is conducted by practitioners operating under some of the most well-developed environmental laws around the globe: California, USA; British Columbia, Canada; Queensland, Australia; and New Zealand. We found that practitioners used a broad and varied definition of impact for CEA, which led to differences in how baseline, scale, and significance were determined. We also found that practice and science are not closely aligned and, as such, we highlight opportunities for managers, policy makers, practitioners, and scientists to improve environmental assessment.

  11. Opportunities and Challenges for the Life Sciences Community

    Science.gov (United States)

    Stewart, Elizabeth; Ozdemir, Vural

    2012-01-01

    Abstract Twenty-first century life sciences have transformed into data-enabled (also called data-intensive, data-driven, or big data) sciences. They principally depend on data-, computation-, and instrumentation-intensive approaches to seek comprehensive understanding of complex biological processes and systems (e.g., ecosystems, complex diseases, environmental, and health challenges). Federal agencies including the National Science Foundation (NSF) have played and continue to play an exceptional leadership role by innovatively addressing the challenges of data-enabled life sciences. Yet even more is required not only to keep up with the current developments, but also to pro-actively enable future research needs. Straightforward access to data, computing, and analysis resources will enable true democratization of research competitions; thus investigators will compete based on the merits and broader impact of their ideas and approaches rather than on the scale of their institutional resources. This is the Final Report for Data-Intensive Science Workshops DISW1 and DISW2. The first NSF-funded Data Intensive Science Workshop (DISW1, Seattle, WA, September 19–20, 2010) overviewed the status of the data-enabled life sciences and identified their challenges and opportunities. This served as a baseline for the second NSF-funded DIS workshop (DISW2, Washington, DC, May 16–17, 2011). Based on the findings of DISW2 the following overarching recommendation to the NSF was proposed: establish a community alliance to be the voice and framework of the data-enabled life sciences. After this Final Report was finished, Data-Enabled Life Sciences Alliance (DELSA, www.delsall.org) was formed to become a Digital Commons for the life sciences community. PMID:22401659

  12. YOUTH LABOUR MARKET. MOBILITY, CAREER DEVELOPMENT, INCOMES. CHALLENGES AND OPPORTUNITIES

    Directory of Open Access Journals (Sweden)

    Vasile Liviu

    2011-07-01

    Full Text Available This paper presents the main characteristics of the youth labour market, with a special view on mobility, career development and incomes. The paper is substantiated by and continues the researches of the authors on the topic of labour force mobility and on the one of adaptability, respectively on youths' beahviour on labour market (with particular consideration of young graduates highlighting the factors that adjust choices regarding taking up a job, career advancement, labour motivation, professional and personal satisfaction opportunities which are provided by the labour market at local level, in country and abroad. Quantitative and qualitative indicators are presented about Romanian youths' labour market within the European context during the transition period. The impact of the crisis on youths' labour market is analysed, highlighting the challenges and opportunities, the particularities of the newly created jobs and especially the knowledge, skills and competencies requirements (KSC. The authors propose both the improvement of the systems of indicators for defining the potential and presence of youth on the labour market, the economic and social impact of external mobility of young graduates and an integrated scheme of policy measures for promoting adaptability and performance integration on Romanian labour market of youth. Particular attention is paid to presenting policy instruments for halting/diminishing the brain drain and brain shopping phenomena by promoting an attractive (professionally and monetary supply for employment in Romania's local economy. The authors succeed in highlighting the functional links between the education market (labour force supply and labour market (employment demand of the business environment underpinning the requirement of integrated management of labour potential in the years preceding studies' finalization and up to the post-insertion years by multi-criteria analysis models and graduate career tracking

  13. Challenges and opportunities for plasma processing of materials

    International Nuclear Information System (INIS)

    McKenzie, D.R.

    1999-01-01

    Full text: Plasma processing of materials is in many ways at a turning point in its development. On the one hand, there are new opportunities arising from the environmental concerns associated with conventional materials processing methods such as electroplating. On the other hand, there are challenges associated with the large capital cost of plant and the demonstration that the new techniques can deliver the quality and quantity required in the market place. An example of such a challenge is file replacement of electroplated chromium by sputtered alternatives in the solar absorber coatings industry. Cathodic arc based processes also offer opportunities for advanced materials processing to displace electroplating. The use of cathodic arcs to coat gold look-alike finishes for architectural applications is well advanced. The challenges for other coatings are essentially dependent on the quality of the adhesion. The combination of the cathodic arc with Plasma Immersion Ion implantation (PI 3 ) technology gives significant improvements in film adhesion. The energy of the incident ions from the cathodic arc may be readily increased to 20 KeV or so without serious difficulties. We have been carrying out trials of a PI 3 type power supply developed by ANSTO, coupled to a continuous type cathodic arc fitted with a magnetic sector filter. The power supply provides short pulses with an adjustable repetition rate and duty cycle. The pulses provide bursts of energetic ions which can be used for assisting the deposition of coatings or for implantation without coating, depending on the location and orientation of the substrate. The results for film adhesion are promising on a number of substrates. The adhesion of metal films on polyimide substrates for example is definitely improved. The modification of polymers to improve their scratch resistance is becoming an important opportunity for plasma processing. Polymers have some valuable properties such as strength to weight ratio

  14. Knowledge management at the IAEA - Challenges and opportunities

    International Nuclear Information System (INIS)

    Yanev, Y.L.; Cherif, S.

    2004-01-01

    Full text: 'Knowledge Management caters to the critical issues of organizational adaptation, survival and competence in face of increasingly discontinuous change of environment. Essentially, it embodies organizational processes that seek synergistic combination of data and information processing capacity of information technologies, and the creative and innovative capacity of human beings' (Malhotra 1997). International organizations are coming to view knowledge as their most valuable and strategic resource, and bringing that knowledge to bear on problems and opportunities as their most important capability. It is being realised that to remain geared to the evolving needs of their Member States it is a must to explicitly manage all intellectual resources and capabilities of the organization. To this end, many international organizations have initiated a range of knowledge management projects and programs. The primary focus of these efforts has been on developing new applications of information technology to support the digital capture, storage, retrieval and distribution of an organization's documented knowledge but also capturing valuable tacit knowledge existing within peoples' heads, augmented or shared via interpersonal interaction and social relationships. Numerous technical and organizational initiatives have been aligned and integrated, providing a comprehensive infrastructure to support knowledge management processes. But while the appropriate infrastructure can enhance an organization's ability to create and exploit knowledge, it does not insure that the organization is making the best investment of its resources or that it is managing the right knowledge in the right way. Against the background of these trends and the opportunities and challenges they present, the Agency has been active in establishing knowledge management as a crosscutting activity that includes both assisting Member States in managing their own nuclear knowledge assets but also in

  15. Smart services – characteristics, challenges, opportunities and business models

    Directory of Open Access Journals (Sweden)

    Marquardt Katrin

    2017-07-01

    Full Text Available “Industry 4.0”, “Digitalization”, “Internet of Things” and “Smart Services” are the today’s buzzwords when tracking economic news. It is to ask about the meaning of those phrases. The world has changed over the last decade from a mainly physical to software controlled economy and the information technology has become an integral part of our industry and society in its entirety. Nowadays it is no longer the product that matters it is the data that are generated by using the product or service. Those usage data collected and analyzed commence new business models and services. The economic future of a company will much more rely on the ability to collect and use the data to generate Smart Services for their customers and to transform from a simple product supplier to an entertainment provider. However there are not only opportunities there are also challenges on the way to that new services which needs to be known and considered. For instance the development cycles need to be faster, the business models need to be adjusted and the positive financial results will not come into the picture on the first day. Based on those thoughts and while there only a handful of researches about that new services exists, the main purpose of the present study is at first, to gain a common understanding about the meaning and the characteristics of Smart Services and their adjacencies. Secondly, the study summarizes the identified challenges and opportunities in relation to them. Thirdly, the author introduce and explain the main business models usable for those Smart Services and the requirements for starting the transformation towards those services. The aim of this paper is to set a basis for this exciting and relatively unsought topic and to produce an interest in further empirical and practical researches in this area. The methodologies used for this research are a systematic literature review and an evaluation of existing studies with the

  16. Citizen observations contributing to flood modelling: opportunities and challenges

    Directory of Open Access Journals (Sweden)

    T. H. Assumpção

    2018-02-01

    Full Text Available Citizen contributions to science have been successfully implemented in many fields, and water resources is one of them. Through citizens, it is possible to collect data and obtain a more integrated decision-making process. Specifically, data scarcity has always been an issue in flood modelling, which has been addressed in the last decades by remote sensing and is already being discussed in the citizen science context. With this in mind, this article aims to review the literature on the topic and analyse the opportunities and challenges that lie ahead. The literature on monitoring, mapping and modelling, was evaluated according to the flood-related variable citizens contributed to. Pros and cons of the collection/analysis methods were summarised. Then, pertinent publications were mapped into the flood modelling cycle, considering how citizen data properties (spatial and temporal coverage, uncertainty and volume are related to its integration into modelling. It was clear that the number of studies in the area is rising. There are positive experiences reported in collection and analysis methods, for instance with velocity and land cover, and also when modelling is concerned, for example by using social media mining. However, matching the data properties necessary for each part of the modelling cycle with citizen-generated data is still challenging. Nevertheless, the concept that citizen contributions can be used for simulation and forecasting is proved and further work lies in continuing to develop and improve not only methods for collection and analysis, but certainly for integration into models as well. Finally, in view of recent automated sensors and satellite technologies, it is through studies as the ones analysed in this article that the value of citizen contributions, complementing such technologies, is demonstrated.

  17. Citizen observations contributing to flood modelling: opportunities and challenges

    Science.gov (United States)

    Assumpção, Thaine H.; Popescu, Ioana; Jonoski, Andreja; Solomatine, Dimitri P.

    2018-02-01

    Citizen contributions to science have been successfully implemented in many fields, and water resources is one of them. Through citizens, it is possible to collect data and obtain a more integrated decision-making process. Specifically, data scarcity has always been an issue in flood modelling, which has been addressed in the last decades by remote sensing and is already being discussed in the citizen science context. With this in mind, this article aims to review the literature on the topic and analyse the opportunities and challenges that lie ahead. The literature on monitoring, mapping and modelling, was evaluated according to the flood-related variable citizens contributed to. Pros and cons of the collection/analysis methods were summarised. Then, pertinent publications were mapped into the flood modelling cycle, considering how citizen data properties (spatial and temporal coverage, uncertainty and volume) are related to its integration into modelling. It was clear that the number of studies in the area is rising. There are positive experiences reported in collection and analysis methods, for instance with velocity and land cover, and also when modelling is concerned, for example by using social media mining. However, matching the data properties necessary for each part of the modelling cycle with citizen-generated data is still challenging. Nevertheless, the concept that citizen contributions can be used for simulation and forecasting is proved and further work lies in continuing to develop and improve not only methods for collection and analysis, but certainly for integration into models as well. Finally, in view of recent automated sensors and satellite technologies, it is through studies as the ones analysed in this article that the value of citizen contributions, complementing such technologies, is demonstrated.

  18. Gradient Models in Molecular Biophysics: Progress, Challenges, Opportunities.

    Science.gov (United States)

    Bardhan, Jaydeep P

    2013-12-01

    In the interest of developing a bridge between researchers modeling materials and those modeling biological molecules, we survey recent progress in developing nonlocal-dielectric continuum models for studying the behavior of proteins and nucleic acids. As in other areas of science, continuum models are essential tools when atomistic simulations (e.g. molecular dynamics) are too expensive. Because biological molecules are essentially all nanoscale systems, the standard continuum model, involving local dielectric response, has basically always been dubious at best. The advanced continuum theories discussed here aim to remedy these shortcomings by adding features such as nonlocal dielectric response, and nonlinearities resulting from dielectric saturation. We begin by describing the central role of electrostatic interactions in biology at the molecular scale, and motivate the development of computationally tractable continuum models using applications in science and engineering. For context, we highlight some of the most important challenges that remain and survey the diverse theoretical formalisms for their treatment, highlighting the rigorous statistical mechanics that support the use and improvement of continuum models. We then address the development and implementation of nonlocal dielectric models, an approach pioneered by Dogonadze, Kornyshev, and their collaborators almost forty years ago. The simplest of these models is just a scalar form of gradient elasticity, and here we use ideas from gradient-based modeling to extend the electrostatic model to include additional length scales. The paper concludes with a discussion of open questions for model development, highlighting the many opportunities for the materials community to leverage its physical, mathematical, and computational expertise to help solve one of the most challenging questions in molecular biology and biophysics.

  19. A new approach to wind energy: Opportunities and challenges

    Science.gov (United States)

    Dabiri, John O.; Greer, Julia R.; Koseff, Jeffrey R.; Moin, Parviz; Peng, Jifeng

    2015-03-01

    Despite common characterizations of modern wind energy technology as mature, there remains a persistent disconnect between the vast global wind energy resource—which is 20 times greater than total global power consumption—and the limited penetration of existing wind energy technologies as a means for electricity generation worldwide. We describe an approach to wind energy harvesting that has the potential to resolve this disconnect by geographically distributing wind power generators in a manner that more closely mirrors the physical resource itself. To this end, technology development is focused on large arrays of small wind turbines that can harvest wind energy at low altitudes by using new concepts of biology-inspired engineering. This approach dramatically extends the reach of wind energy, as smaller wind turbines can be installed in many places that larger systems cannot, especially in built environments. Moreover, they have lower visual, acoustic, and radar signatures, and they may pose significantly less risk to birds and bats. These features can be leveraged to attain cultural acceptance and rapid adoption of this new technology, thereby enabling significantly faster achievement of state and national renewable energy targets than with existing technology alone. Favorable economics stem from an orders-of-magnitude reduction in the number of components in a new generation of simple, mass-manufacturable (even 3D-printable), vertical-axis wind turbines. However, this vision can only be achieved by overcoming significant scientific challenges that have limited progress over the past three decades. The following essay summarizes our approach as well as the opportunities and challenges associated with it, with the aim of motivating a concerted effort in basic and applied research in this area.

  20. Gradient Models in Molecular Biophysics: Progress, Challenges, Opportunities

    Science.gov (United States)

    Bardhan, Jaydeep P.

    2014-01-01

    In the interest of developing a bridge between researchers modeling materials and those modeling biological molecules, we survey recent progress in developing nonlocal-dielectric continuum models for studying the behavior of proteins and nucleic acids. As in other areas of science, continuum models are essential tools when atomistic simulations (e.g. molecular dynamics) are too expensive. Because biological molecules are essentially all nanoscale systems, the standard continuum model, involving local dielectric response, has basically always been dubious at best. The advanced continuum theories discussed here aim to remedy these shortcomings by adding features such as nonlocal dielectric response, and nonlinearities resulting from dielectric saturation. We begin by describing the central role of electrostatic interactions in biology at the molecular scale, and motivate the development of computationally tractable continuum models using applications in science and engineering. For context, we highlight some of the most important challenges that remain and survey the diverse theoretical formalisms for their treatment, highlighting the rigorous statistical mechanics that support the use and improvement of continuum models. We then address the development and implementation of nonlocal dielectric models, an approach pioneered by Dogonadze, Kornyshev, and their collaborators almost forty years ago. The simplest of these models is just a scalar form of gradient elasticity, and here we use ideas from gradient-based modeling to extend the electrostatic model to include additional length scales. The paper concludes with a discussion of open questions for model development, highlighting the many opportunities for the materials community to leverage its physical, mathematical, and computational expertise to help solve one of the most challenging questions in molecular biology and biophysics. PMID:25505358

  1. Gradient models in molecular biophysics: progress, challenges, opportunities

    Science.gov (United States)

    Bardhan, Jaydeep P.

    2013-12-01

    In the interest of developing a bridge between researchers modeling materials and those modeling biological molecules, we survey recent progress in developing nonlocal-dielectric continuum models for studying the behavior of proteins and nucleic acids. As in other areas of science, continuum models are essential tools when atomistic simulations (e.g., molecular dynamics) are too expensive. Because biological molecules are essentially all nanoscale systems, the standard continuum model, involving local dielectric response, has basically always been dubious at best. The advanced continuum theories discussed here aim to remedy these shortcomings by adding nonlocal dielectric response. We begin by describing the central role of electrostatic interactions in biology at the molecular scale, and motivate the development of computationally tractable continuum models using applications in science and engineering. For context, we highlight some of the most important challenges that remain, and survey the diverse theoretical formalisms for their treatment, highlighting the rigorous statistical mechanics that support the use and improvement of continuum models. We then address the development and implementation of nonlocal dielectric models, an approach pioneered by Dogonadze, Kornyshev, and their collaborators almost 40 years ago. The simplest of these models is just a scalar form of gradient elasticity, and here we use ideas from gradient-based modeling to extend the electrostatic model to include additional length scales. The review concludes with a discussion of open questions for model development, highlighting the many opportunities for the materials community to leverage its physical, mathematical, and computational expertise to help solve one of the most challenging questions in molecular biology and biophysics.

  2. Opportunities and challenges to promoting oral health in primary schools.

    Science.gov (United States)

    Gill, P; Chestnutt, I G; Channing, D

    2009-09-01

    Inequalities in oral health in areas of socio-economic disadvantage are well recognised. As children spend a considerable proportion of their lives in education, schools can play a significant role in promoting children's health and oral health. However, to what extent schools are able to do this is unclear. The aim of this study was therefore to investigate opportunities and challenges to promoting oral health in primary schools. A purposive sample of 20 primary schools from socially and economically disadvantaged areas of Cardiff, UK were selected to participate in this qualitative study. Data were collected through semi-structured interviews conducted with head teachers or their nominated deputies. General awareness of health and oral health was good, with all schools promoting the consumption of fruit, water and milk and discouraging products such as carbonated drinks and confectionaries. Health promotion schemes wereimplemented primarily to improve the health of the children, although schools felt they also offered the potential to improve classroom behaviour and attendance. However, oral health was viewed as a separate entity to general health and perceived to be inadequately promoted. Successful health promotion schemes were also influenced by the attitudes of headteachers. Most schools had no or limited links with local dental services and, or oral health educators, although such input, when it occurred, was welcomed and highly valued. Knowledge of how to handle dental emergencies was limited and only two schools operated toothbrushing schemes, although all expressed an interest in such programmes. This study identified a positive predisposition to promoting health in primary schools. The challenge for the dental team, however, is to promote and integrate oral health into mainstream health promotion activities in schools. The paper also makes recommendations for further research.

  3. Powder Materials and Energy Efficiency in Transportation: Opportunities and Challenges

    Science.gov (United States)

    Marquis, Fernand D. S.

    2012-03-01

    The transportation industry accounts for one quarter of global energy use and has by far the largest share of global oil consumption. It used 51.5% of the oil worldwide in 2003. Mobility projections show that it is expected to triple by 2050 with associated energy use. Considerable achievements recently have been obtained in the development of powder and powder-processed metallic alloys, metal matrix composites, intermetallics, and carbon fiber composites. These achievements have resulted in their introduction to the transportation industry in a wide variety of transportation components with significant impact on energy efficiency. A significant number of nano, nanostructured, and nanohybrid materials systems have been deployed. Others, some of them incorporating carbon nanotubes and graphene, are under research and development and exhibit considerable potential. Airplane redesign using a materials and functional systems integration approach was used resulting in considerable system improvements and energy efficiency. It is expected that this materials and functional systems integration soon will be adopted in the design and manufacture of other advanced aircrafts and extended to the automotive industry and then to the marine transportation industry. The opportunities for the development and application of new powder materials in the transportation industry are extensive, with considerable potential to impact energy utilization. However, significant challenges need to be overcome in several critical areas.

  4. Challenges and Opportunities for Sustainable Tourism Development in Ulithi Atoll

    Directory of Open Access Journals (Sweden)

    Anna Ongaro

    2016-07-01

    Full Text Available This article aims to analyze the tourism potential of Ulithi Atoll, in the Federated States of Micronesia. It identifies possibilities for sustainable tourism development, while taking into account the major issues that threaten the environment, the cultural integrity and the future of the local community. Through a review of existing research and an assessment of the web presence, the study develops a diagnosis of the current situation of the tourism sector in the destination. The tourism potential of Ulithi mainly relies on its beautiful physical environment and authentic cultural heritage, but it is still largely untapped due to limited development. Tourism represents a strategic tool for the economic growth and empowerment of Ulithi community. Presently, however, the atoll’s biggest problem is the recovery from the recent disastrous Typhoon Maysak. Other pressing challenges are climate change and the erosion of traditional knowledge. The study identifies ecotourism and voluntourism as key niche market opportunities for the destination. Encouraging greater participation among the stakeholders and a concrete commitment to sustainability within the strategic plans are some of the recommendations that aim to build the tourism industry in a way that supports the local culture, the natural resources and the way of life.

  5. Challenges and opportunities for audiovisual diversity in the Internet

    Directory of Open Access Journals (Sweden)

    Trinidad García Leiva

    2017-06-01

    Full Text Available http://dx.doi.org/10.5007/2175-7984.2017v16n35p132 At the gates of the first quarter of the XXI century, nobody doubts the fact that the value chain of the audiovisual industry has suffered important transformations. The digital era presents opportunities for cultural enrichment as well as displays new challenges. After presenting a general portray of the audiovisual industries in the digital era, taking as a point of departure the Spanish case and paying attention to players and logics in tension, this paper will present some notes about the advantages and disadvantages that exist for the diversity of audiovisual production, distribution and consumption online. It is here sustained that the diversity of the audiovisual sector online is not guaranteed because the formula that has made some players successful and powerful is based on walled-garden models to monetize contents (which, besides, add restrictions to their reproduction and circulation by and among consumers. The final objective is to present some ideas about the elements that prevent the strengthening of the diversity of the audiovisual industry in the digital scenario. Barriers to overcome are classified as technological, financial, social, legal and political.

  6. Preparing for Change: Challenges and Opportunities in a Global World

    Science.gov (United States)

    O'Hara, Sabine

    2009-03-01

    Our world is becoming increasingly global. This may sound like a clich'e, yet it is true nonetheless, and poses unprecedented challenges for graduate education. For the new generation of researchers, teachers and professionals to be successful they must be prepared in more than the content area of their chosen field. They must also acquire proficiency in global awareness, cultural literacy, multicultural teamwork and language facility. These global skill sets form the basis for effective multicultural collaboration and will become increasingly important even for those who do not intend to study or work abroad. Knowledge has become more portable in the internet age; large data bases and reports can be accessed in real time from various locations around the globe; information is exchanged in multifaceted knowledge networks; collaborative research takes place within and outside of the traditional venue of the research university in the private sector, research institutes, and associations; research networks span multiple disciplines as progress invariably occurs at the intersection of previously discrete fields of inquiry. Global collaboration thus is no longer dependent on the physical proximity of collaborators but can take place anywhere any time. This then requires yet another set of skills, namely the ability to adapt to change, exhibit flexibility and transfer skills to a range of contexts and applications. Effective graduate education must address these realities and expose students to learning opportunities that will enable them to acquire these much needed global skills sets.

  7. Challenges and opportunities of biodegradable plastics: A mini review.

    Science.gov (United States)

    Rujnić-Sokele, Maja; Pilipović, Ana

    2017-02-01

    The concept of materials coming from nature with environmental advantages of being biodegradable and/or biobased (often referred to as bioplastics) is very attractive to the industry and to the consumers. Bioplastics already play an important role in the fields of packaging, agriculture, gastronomy, consumer electronics and automotive, but still they have a very low share in the total production of plastics (currently about 1% of the about 300 million tonnes of plastic produced annually). Biodegradable plastics are often perceived as the possible solution for the waste problem, but biodegradability is just an additional feature of the material to be exploited at the end of its life in specific terms, in the specific disposal environment and in a specific time, which is often forgotten. They should be used as a favoured choice for the applications that demand a cheap way to dispose of the item after it has fulfilled its job (e.g. for food packaging, agriculture or medical products). The mini-review presents the opportunities and future challenges of biodegradable plastics, regarding processing, properties and waste management options.

  8. Optimizing transuranic waste management-challenges and opportunities

    International Nuclear Information System (INIS)

    Triay, I.R.; Wu, C.F.; Moody, D.C.; Jennings, S.G.

    2002-01-01

    The opening of the Waste Isolation Pilot Plant (WIPP) for disposal of transuranic (TRU) waste in March of 1999, the granting of the Hazardous Waste Facility Permit in November 1999, and over two years of operational experience have demonstrated the Department of Energy's (DOE'S) capability in closing the nuclear energy cycle. While these achievements resolved several scientific, engineering, regulatory and political issues, the DOE has identified a new set of challenges that represent opportunities for improving programmatic efficiency, cost-effectiveness, and operational safety in managing the nation's TRU waste. The DOE has recognized that the complex administrative and regulatory requirements for characterization, transportation and disposal of TRU waste are costly (1). A review by the National Academy of Sciences (NAS) states that these requirements lead to inefficient waste characterization, handling and transportation operations that in turn can lead to unnecessary radiation exposure to workers without a commensurate decrease in risk to the public and the environment (2). This paper provides an overview of the status of the WJPP repository, explains the principles of the proposed commercial business approach, and describes some of the proposed major enhancements of the TRU waste transportation systems. The DOE is developing a remote-handled (RH) waste program to enable emplacement of RH waste at WPP. This program includes appropriate facility modifications and regulatory changes (3).

  9. Mechanisms of motivation–cognition interaction: challenges and opportunities

    Science.gov (United States)

    Krug, Marie K.; Chiew, Kimberly S.; Kool, Wouter; Westbrook, J. Andrew; Clement, Nathan J.; Adcock, R. Alison; Barch, Deanna M.; Botvinick, Matthew M.; Carver, Charles S.; Cools, Roshan; Custers, Ruud; Dickinson, Anthony; Dweck, Carol S.; Fishbach, Ayelet; Gollwitzer, Peter M.; Hess, Thomas M.; Isaacowitz, Derek M.; Mather, Mara; Murayama, Kou; Pessoa, Luiz; Samanez-Larkin, Gregory R.; Somerville, Leah H.

    2016-01-01

    Recent years have seen a rejuvenation of interest in studies of motivation–cognition interactions arising from many different areas of psychology and neuroscience. The present issue of Cognitive, Affective, & Behavioral Neuroscience provides a sampling of some of the latest research from a number of these different areas. In this introductory article, we provide an overview of the current state of the field, in terms of key research developments and candidate neural mechanisms receiving focused investigation as potential sources of motivation–cognition interaction. However, our primary goal is conceptual: to highlight the distinct perspectives taken by different research areas, in terms of how motivation is defined, the relevant dimensions and dissociations that are emphasized, and the theoretical questions being targeted. Together, these distinctions present both challenges and opportunities for efforts aiming toward a more unified and cross-disciplinary approach. We identify a set of pressing research questions calling for this sort of cross-disciplinary approach, with the explicit goal of encouraging integrative and collaborative investigations directed toward them. PMID:24920442

  10. Opportunities and challenges for evaluating precipitation estimates during GPM mission

    Energy Technology Data Exchange (ETDEWEB)

    Amitai, E. [George Mason Univ. and NASA Goddard Space Flight Center, Greenbelt, MD (United States); NASA Goddard Space Flight Center, Greenbelt, MD (United States); Llort, X.; Sempere-Torres, D. [GRAHI/Univ. Politecnica de Catalunya, Barcelona (Spain)

    2006-10-15

    Data assimilation in conjunction with numerical weather prediction and a variety of hydrologic applications now depend on satellite observations of precipitation. However, providing values of precipitation is not sufficient unless they are accompanied by the associated uncertainty estimates. The main approach of quantifying satellite precipitation uncertainties generally requires establishment of reliable uncertainty estimates for the ground validation rainfall products. This paper discusses several of the relevant validation concepts evolving from the tropical rainfall measuring mission (TRMM) era to the global precipitation measurement mission (GPM) era in the context of determining and reducing uncertainties of ground and space-based radar rainfall estimates. From comparisons of probability distribution functions of rain rates derived from TRMM precipitation radar and co-located ground based radar data - using the new NASA TRMM radar rainfall products (version 6) - this paper provides (1) a brief review of the importance of comparing pdfs of rain rate for statistical and physical verification of space-borne radar estimates of precipitation; (2) a brief review of how well the ground validation estimates compare to the TRMM radar retrieved estimates; and (3) discussion on opportunities and challenges to determine and reduce the uncertainties in space-based and ground-based radar estimates of rain rate distributions. (orig.)

  11. GLOBALIZATION AND SMALL BUSINESSES AND ECONOMIES – CHALLENGES AND OPPORTUNITIES

    Directory of Open Access Journals (Sweden)

    NINKO KOSTOVSKI

    2016-08-01

    Full Text Available In this paper, we analyze the effect of globalization in general and from the viewpoint of the small and medium sized companies in the Republic of Macedonia, as a typical developing economy. Our survey of 100 managers and business owners from small and medium sized enterprises indicates that they tend to perceive the globalization with more conservative glasses as negative, or at the best, as a neutral phenomenon to their overall business prospects. However, to harvest the apparent opportunities of the globalization and to achieve the desired internationalization of their businesses, they call for intensive regional cooperation seeing it as a gateway to much harsher realms of the globalized market. The literature review and the examples from some other countries support these conservative standing of our managers and offer practical explanations why the approach towards the globalization is conservative and often even negative. Small business is important provider of new jobs, ideas and business concepts. However, with the opening of the global market it is a constant pursue for customers all around the world, having to meet their diverse and rapidly changing needs and facing extremely shortened delivery terms and product lifecycles. Many small companies, particularly from the developing countries are not adequately prepared to face the reality of this challenge. On the other hand, the big multinational companies receive more than hefty incentives to invest into the developing countries and that creates additional negative sentiments towards the globalization among the local companies.

  12. ACR-1000TM Project - Licensing Opportunities and Challenges

    International Nuclear Information System (INIS)

    Popov, N.; Doerffer, S.; Ion, R.; Hopwood, J.

    2011-01-01

    Atomic Energy of Canada Limited (AECL) has developed the Advanced CANDU Reactor TM 1 1000 (ACR-1000 TM ) as an evolutionary advancement of the current CANDU 6 reactor. The ACR-1000 design has evolved from AECL's in-depth knowledge of CANDU TM systems, components, and materials, as well as the experience and feedback received from owners and operators of CANDU plants. The ACR design retains the proven strengths and features of CANDU reactors, while incorporating innovations and state-of-the-art technology. It also features major improvements in economics, inherent safety characteristics, and performance, while retaining the proven benefits of the CANDU family of nuclear power plants. To ensure that the ACR design is compliant with Canadian and international requirements, regulatory pre-project reviews of the ACR-1000 (and ACR-700 TM 1 with lower output) were conducted early in the design work. The regulatory feedback from these pre-project regulatory reviews helped AECL to better understand regulatory expectations in Canada, US and the UK, and to make further advancements and improvements in the ACR design to meet the Canadian and international regulatory requirements. This paper provides an overview of the key design features of the ACR-1000 reactor design, and summary of the pre-project reviews by those above-mentioned regulatory bodies, demonstrating opportunities and challenges in licensing process of and pointing to the importance of efficient vendor-regulator interaction. (author)

  13. Engineering and physical sciences in oncology: challenges and opportunities.

    Science.gov (United States)

    Mitchell, Michael J; Jain, Rakesh K; Langer, Robert

    2017-11-01

    The principles of engineering and physics have been applied to oncology for nearly 50 years. Engineers and physical scientists have made contributions to all aspects of cancer biology, from quantitative understanding of tumour growth and progression to improved detection and treatment of cancer. Many early efforts focused on experimental and computational modelling of drug distribution, cell cycle kinetics and tumour growth dynamics. In the past decade, we have witnessed exponential growth at the interface of engineering, physics and oncology that has been fuelled by advances in fields including materials science, microfabrication, nanomedicine, microfluidics, imaging, and catalysed by new programmes at the National Institutes of Health (NIH), including the National Institute of Biomedical Imaging and Bioengineering (NIBIB), Physical Sciences in Oncology, and the National Cancer Institute (NCI) Alliance for Nanotechnology. Here, we review the advances made at the interface of engineering and physical sciences and oncology in four important areas: the physical microenvironment of the tumour and technological advances in drug delivery; cellular and molecular imaging; and microfluidics and microfabrication. We discussthe research advances, opportunities and challenges for integrating engineering and physical sciences with oncology to develop new methods to study, detect and treat cancer, and we also describe the future outlook for these emerging areas.

  14. Mechanics of the brain: perspectives, challenges, and opportunities.

    Science.gov (United States)

    Goriely, Alain; Geers, Marc G D; Holzapfel, Gerhard A; Jayamohan, Jayaratnam; Jérusalem, Antoine; Sivaloganathan, Sivabal; Squier, Waney; van Dommelen, Johannes A W; Waters, Sarah; Kuhl, Ellen

    2015-10-01

    The human brain is the continuous subject of extensive investigation aimed at understanding its behavior and function. Despite a clear evidence that mechanical factors play an important role in regulating brain activity, current research efforts focus mainly on the biochemical or electrophysiological activity of the brain. Here, we show that classical mechanical concepts including deformations, stretch, strain, strain rate, pressure, and stress play a crucial role in modulating both brain form and brain function. This opinion piece synthesizes expertise in applied mathematics, solid and fluid mechanics, biomechanics, experimentation, material sciences, neuropathology, and neurosurgery to address today's open questions at the forefront of neuromechanics. We critically review the current literature and discuss challenges related to neurodevelopment, cerebral edema, lissencephaly, polymicrogyria, hydrocephaly, craniectomy, spinal cord injury, tumor growth, traumatic brain injury, and shaken baby syndrome. The multi-disciplinary analysis of these various phenomena and pathologies presents new opportunities and suggests that mechanical modeling is a central tool to bridge the scales by synthesizing information from the molecular via the cellular and tissue all the way to the organ level.

  15. BC's oil and gas industry : opportunities and challenges

    International Nuclear Information System (INIS)

    Alvarez, P.

    2003-01-01

    An update of the Canadian petroleum and natural gas industry was presented with reference to activity trends and major issues. The presentation also described opportunities and challenges facing the industry in British Columbia and reviewed the impact of federal policies on BC. In recent years the industry has moved to oil sands and unconventional gas, offshore sites, and coalbed methane development. Other changes are a result of technology which makes it possible to drill deeper and faster while having less environmental impact. Government issues have become increasingly complex, however. Industry capital spending from 2000 to 2003 was presented for Northern Canada, the east coast offshore, Alberta, the Western Canada Sedimentary Basin, oil sand deposits, and international activities. The presentation included several graphs depicting: the changing natural gas production mix; North American natural gas demand; wells drilled by province; natural gas resources in BC; upstream capital spending in BC; wells drilled by type and depth in BC; top natural gas wells in 2000 and 2002; natural gas production in BC; finding and development costs for Canadian natural gas; and, the widening gap of the federal income tax rate between oil and natural gas and other industries. British Columbia is in the strategic position of having significant untapped gas potential in the northeastern part of the province. For now, there is sufficient pipeline capacity to bring the gas to markets in the United States where there is a strong demand for electric power generation. 16 figs

  16. Hydrological connectivity for riverine fish: measurement challenges and research opportunities

    Science.gov (United States)

    Fullerton, A.H.; Burnett, K.M.; Steel, E.A.; Flitcroft, R.L.; Pess, G.R.; Feist, B.E.; Torgersen, Christian E.; Miller, D.J.; Sanderson, B.L.

    2010-01-01

    In this review, we first summarize how hydrologic connectivity has been studied for riverine fish capable of moving long distances, and then identify research opportunities that have clear conservation significance. Migratory species, such as anadromous salmonids, are good model organisms for understanding ecological connectivity in rivers because the spatial scale over which movements occur among freshwater habitats is large enough to be easily observed with available techniques; they are often economically or culturally valuable with habitats that can be easily fragmented by human activities; and they integrate landscape conditions from multiple surrounding catchment(s) with in‐river conditions. Studies have focussed on three themes: (i) relatively stable connections (connections controlled by processes that act over broad spatio‐temporal scales >1000 km2 and >100 years); (ii) dynamic connections (connections controlled by processes acting over fine to moderate spatio‐temporal scales ∼1–1000 km2 and hydrologic connectivity, including actions that disrupt or enhance natural connections experienced by fish.We outline eight challenges to understanding the role of connectivity in riverine fish ecology, organized under three foci: (i) addressing the constraints of river structure; (ii) embracing temporal complexity in hydrologic connectivity; and (iii) managing connectivity for riverine fishes. Challenges include the spatial structure of stream networks, the force and direction of flow, scale‐dependence of connectivity, shifting boundaries, complexity of behaviour and life histories and quantifying anthropogenic influence on connectivity and aligning management goals. As we discuss each challenge, we summarize relevant approaches in the literature and provide additional suggestions for improving research and management of connectivity for riverine fishes.Specifically, we suggest that rapid advances are possible in the following arenas: (i

  17. Challenges and opportunities for integrating lake ecosystem modelling approaches

    Science.gov (United States)

    Mooij, Wolf M.; Trolle, Dennis; Jeppesen, Erik; Arhonditsis, George; Belolipetsky, Pavel V.; Chitamwebwa, Deonatus B.R.; Degermendzhy, Andrey G.; DeAngelis, Donald L.; Domis, Lisette N. De Senerpont; Downing, Andrea S.; Elliott, J. Alex; Ruberto, Carlos Ruberto; Gaedke, Ursula; Genova, Svetlana N.; Gulati, Ramesh D.; Hakanson, Lars; Hamilton, David P.; Hipsey, Matthew R.; Hoen, Jochem 't; Hulsmann, Stephan; Los, F. Hans; Makler-Pick, Vardit; Petzoldt, Thomas; Prokopkin, Igor G.; Rinke, Karsten; Schep, Sebastiaan A.; Tominaga, Koji; Van Dam, Anne A.; Van Nes, Egbert H.; Wells, Scott A.; Janse, Jan H.

    2010-01-01

    A large number and wide variety of lake ecosystem models have been developed and published during the past four decades. We identify two challenges for making further progress in this field. One such challenge is to avoid developing more models largely following the concept of others ('reinventing the wheel'). The other challenge is to avoid focusing on only one type of model, while ignoring new and diverse approaches that have become available ('having tunnel vision'). In this paper, we aim at improving the awareness of existing models and knowledge of concurrent approaches in lake ecosystem modelling, without covering all possible model tools and avenues. First, we present a broad variety of modelling approaches. To illustrate these approaches, we give brief descriptions of rather arbitrarily selected sets of specific models. We deal with static models (steady state and regression models), complex dynamic models (CAEDYM, CE-QUAL-W2, Delft 3D-ECO, LakeMab, LakeWeb, MyLake, PCLake, PROTECH, SALMO), structurally dynamic models and minimal dynamic models. We also discuss a group of approaches that could all be classified as individual based: super-individual models (Piscator, Charisma), physiologically structured models, stage-structured models and trait-based models. We briefly mention genetic algorithms, neural networks, Kalman filters and fuzzy logic. Thereafter, we zoom in, as an in-depth example, on the multi-decadal development and application of the lake ecosystem model PCLake and related models (PCLake Metamodel, Lake Shira Model, IPH-TRIM3D-PCLake). In the discussion, we argue that while the historical development of each approach and model is understandable given its 'leading principle', there are many opportunities for combining approaches. We take the point of view that a single 'right' approach does not exist and should not be strived for. Instead, multiple modelling approaches, applied concurrently to a given problem, can help develop an integrative

  18. Object-based Landslide Mapping: Examples, Challenges and Opportunities

    Science.gov (United States)

    Hölbling, Daniel; Eisank, Clemens; Friedl, Barbara; Chang, Kang-Tsung; Tsai, Tsai-Tsung; Birkefeldt Møller Pedersen, Gro; Betts, Harley; Cigna, Francesca; Chiang, Shou-Hao; Aubrey Robson, Benjamin; Bianchini, Silvia; Füreder, Petra; Albrecht, Florian; Spiekermann, Raphael; Weinke, Elisabeth; Blaschke, Thomas; Phillips, Chris

    2016-04-01

    types of landslides. Unlike in these northern European countries, landslides in Taiwan can be effectively delineated based on spectral differences as the surrounding is most often densely vegetated. In this tropical/subtropical region the fast information provision after Typhoon events is important. This need can be addressed in OBIA by automatically calculating thresholds based on vegetation indices and using them for a first rough identification of areas affected by landslides. Moreover, the differentiation in landslide source and transportation area is of high relevance in Taiwan. Finally, an example from New Zealand, where landslide inventory mapping is important for estimating surface erosion, will demonstrate the performance of OBIA compared to visual expert interpretation and on-screen mapping. The associated challenges and opportunities related to case studies in each of these regions are discussed and reviewed. In doing so, open research issues in object-based landslide mapping based on EO data are identified and highlighted.

  19. [The challenges of sustainable development in healthcare facilities].

    Science.gov (United States)

    Mourgues, François; Muret, Jane; Pauchard, Jean-Claude

    2018-03-01

    Healthcare and medical-social facilities have a major responsibility within society, that of the quality of care, but also that of developing a system of sustainable and socially-responsible health. This system must meet the three pillars which constitute such an approach: economic, social and environmental sustainability. Innovation remains central to the sustainable evolution of practices and the first results are now visible. Copyright © 2018 Elsevier Masson SAS. All rights reserved.

  20. Article Commentary: Integral Healthcare: The Benefits and Challenges of Integrating Complementary and Alternative Medicine with a Conventional Healthcare Practice

    Directory of Open Access Journals (Sweden)

    Christina L. Ross PhD

    2009-01-01

    Full Text Available Today's medicine is in the midst of an undeniable crisis. Calls to reform healthcare are in the forefront of economic and political discussions worldwide. Economic pressures reduce the amount of time physicians can spend with patients contributing to burnout among medical staff and endangering the patient iatrogenically. Politicians are getting involved as the public is calling for more affordable healthcare. A new paradigm must be embraced in order to address all aspects of this dilemma. It is clear that science and technology have resulted in vastly improved understanding, diagnosis, and treatment of disease, but the emphasis on science and technology to the exclusion of other elements of healing has also served to limit the development of a model that humanizes healthcare. The healing of a patient must include more than the biology and chemistry of their physical body; by necessity, it must include the mental, emotional and spiritual aspects. Because of these challenges, the development of an integral healthcare system that is rooted in appropriate regulation and supported by rigorous scientific evidence is the direction that many models of integrative healthcare are moving towards in the 21st century.

  1. Elderly and long-term care trends and policy in Taiwan: Challenges and opportunities for health care professionals

    Directory of Open Access Journals (Sweden)

    Hsiu-Hung Wang

    2012-09-01

    Full Text Available The purpose of this article is to address the trends and policy of elderly and long-term care in Taiwan. In response to the increasing demand of an aging society, healthcare professionals play crucial roles in elderly and long-term care and quality assurance of services. This article focuses on the current situation of elderly health care, demands of long-term care, long-term care policy in Taiwan, draft of the Long-term Care Services Act, and draft of the Long-term Care Insurance Act. After the 10-year long-term care project was proposed by the Taiwan government, the supply of health care services and demand for long-term care have created many challenges and opportunities for innovative health professional development. Challenges consist of low old dependency ratio caused by low birth rate, lack of elderly and long-term care related manpower, services and education reform related to long-term care for the future society, and interprofessional collaboration and team work of long-term care. Opportunities include expanding the roles and the career pathways of healthcare professionals, promoting the concepts of active aging and good quality of life, and developing industrial cooperation related to long-term care services. Under these circumstances, healthcare professonals are actively involved in practice, education and research of long-term care services that ensure elderly and disabled people can live a healthier and better life.

  2. Mapping opportunities and challenges for rewilding in Europe

    Science.gov (United States)

    Ceaușu, Silvia; Hofmann, Max; Navarro, Laetitia M; Carver, Steve; Verburg, Peter H; Pereira, Henrique M

    2015-01-01

    Farmland abandonment takes place across the world due to socio-economic and ecological drivers. In Europe agricultural and environmental policies aim to prevent abandonment and halt ecological succession. Ecological rewilding has been recently proposed as an alternative strategy. We developed a framework to assess opportunities for rewilding across different dimensions of wilderness in Europe. We mapped artificial light, human accessibility based on transport infrastructure, proportion of harvested primary productivity (i.e., ecosystem productivity appropriated by humans through agriculture or forestry), and deviation from potential natural vegetation in areas projected to be abandoned by 2040. At the continental level, the levels of artificial light were low and the deviation from potential natural vegetation was high in areas of abandonment. The relative importance of wilderness metrics differed regionally and was strongly connected to local environmental and socio-economic contexts. Large areas of projected abandonment were often located in or around Natura 2000 sites. Based on these results, we argue that management should be tailored to restore the aspects of wilderness that are lacking in each region. There are many remaining challenges regarding biodiversity in Europe, but megafauna species are already recovering. To further potentiate large-scale rewilding, Natura 2000 management would need to incorporate rewilding approaches. Our framework can be applied to assessing rewilding opportunities and challenges in other world regions, and our results could guide redirection of subsidies to manage social-ecological systems. Mapeo de Oportunidades y Retos para el Retorno de la Vida Silvestre Resumen El abandono de tierras agrícolas ocurre en todo el mundo debido a factores socio-económicos y ecológicos. En Europa, las políticas ambientales y agrícolas tienen el objetivo de prevenir el abandono y frenar la sucesión ecológica. La reintroducción o el retorno

  3. Experiencing WPS services in several application domains: opportunities and challenges

    Science.gov (United States)

    lovergine, francesco paolo; tarantino, cristina; d'addabbo, annarita; adamo, patrizia; giuseppe, satalino; refice, alberto; blonda, palma; vicario, saverio

    2016-04-01

    Experiencing WPS services in several application domains: opportunities and challenges ====================================================================================== The implementation of OGC web services and specifically of WPS services revealed itself as a key aspect in order to encourage openess attitude of scientific investigators within several application domains. It can benefit scientific research under different regards, even considering the possibility to promote interoperability, modularity, and the possibility opened by web modeling and the workflow paradigm explotation. Nevertheless it is still a challenging activity and specifically processing services still seem being at an early stage of maturity. This work is about exploitation activities conducted within the GEO GEOSS AIP-8 call by focusing on several applications, such as biodiversity, flood monitoring and soil moisture computation, with implementations based on the pyWPS framework for WPS 1.0 as available at the time of this work. We will present results, lessons learnt and limits found in using those services for distributing demo processing models, along with pro and cons in our experience. References: Refice, A., Capolongo, D., Pasquariello, G., D'Addabbo, A., Bovenga, F., Nutricato, Lovergine F.P., R., Pietranera, L. (2014). SAR and InSAR for Flood Monitoring: Examples With COSMO-SkyMed Data. IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 7(7), 2711--722. F. Mattia, G. Satalino, A. Balenzano, V. Pauwels, E. De Lathauwer, "GMES Sentinel-1 soil moisture algorithm development", Final report for the European Space Agency, ESA ESTEC Contract No. 4000101352/10 /NL/MP/ef, 30 Nov. 2011. V. Tomaselli, P. Dimopoulos, C. Marangi, A. S. Kallimanis, M. Adamo, C. Tarantino, M. Panitsa, M. Terzi, G. Veronico, F. Lovergine, H. Nagendra, R. Lucas, P. Mairota, C.A. Mucher, P. Blonda, "Translating land cover/land use classifications to habitat taxonomies for landscape

  4. International ESCO business opportunities and challenges: a Japanese case study

    Energy Technology Data Exchange (ETDEWEB)

    Vine, E. [Lawrence Berkeley National Lab., CA (United States). Environmental Energy Technologies Div.; Murakoshi, C. [Jyukankyo Research Inst., Tokyo (Japan)

    1997-10-01

    Recently, US energy service companies (ESCOs) have begun to actively explore markets outside the US. Despite the needs of many countries for ESCO involvement, ESCOs face many challenges (i.e., marketing, financial, institutional, political and cultural barriers). Consequently, most of these firms pursue international project opportunities very selectively due to the costs and risks associated with project development. Despite these barriers, some ESCOs view international work as a strategic expansion of their business, assuming that there will be adequate business in the future to repay them for their initial investment. In this paper, the authors present the findings from a recently completed study on the proposed development of an ESCO industry in Japan. The study was based on four sources of information: (1) a review of the published and unpublished literature on ESCOs; (2) interviews with 26 ESCOs in the US, the US Department of Energy, and the National Association of Energy Service Companies (NAESCO); (3) ESCO presentations at the October 1996 NAESCO meeting; and (4) informal discussions with ESCO experts in the US. They believe that the lessons learned in this study can be transferred or applied to other countries interested in developing an ESCO industry. While energy prices have remained relatively stable over the last several years in Japan and energy capacity is not perceived as a near-term problem, other ``market drivers`` necessary for the emergence of a successful and vibrant ESCO industry exist in Japan. Despite the presence of these market drivers, significant barriers to the successful development of an ESCO industry exist in Japan.

  5. International ESCO business opportunities and challenges: a Japanese case study

    International Nuclear Information System (INIS)

    Vine, E.

    1997-10-01

    Recently, US energy service companies (ESCOs) have begun to actively explore markets outside the US. Despite the needs of many countries for ESCO involvement, ESCOs face many challenges (i.e., marketing, financial, institutional, political and cultural barriers). Consequently, most of these firms pursue international project opportunities very selectively due to the costs and risks associated with project development. Despite these barriers, some ESCOs view international work as a strategic expansion of their business, assuming that there will be adequate business in the future to repay them for their initial investment. In this paper, the authors present the findings from a recently completed study on the proposed development of an ESCO industry in Japan. The study was based on four sources of information: (1) a review of the published and unpublished literature on ESCOs; (2) interviews with 26 ESCOs in the US, the US Department of Energy, and the National Association of Energy Service Companies (NAESCO); (3) ESCO presentations at the October 1996 NAESCO meeting; and (4) informal discussions with ESCO experts in the US. They believe that the lessons learned in this study can be transferred or applied to other countries interested in developing an ESCO industry. While energy prices have remained relatively stable over the last several years in Japan and energy capacity is not perceived as a near-term problem, other ''market drivers'' necessary for the emergence of a successful and vibrant ESCO industry exist in Japan. Despite the presence of these market drivers, significant barriers to the successful development of an ESCO industry exist in Japan

  6. Opportunities and challenges for collaborative funding with industry

    Science.gov (United States)

    Thompson, J. F.

    2014-12-01

    The discovery and extraction of natural resources represents major challenges on both technical and socio-political fronts. Societal demand for commodities continues to increase as population, infrastructure, energy demands and standards of living increase. In parallel, society expects more efficient, cleaner and more sustainable practices. There are therefore multiple incentives for industry to invest in research and innovation to meet these fundamental goals. Natural resource companies fund research internally and externally but the focus, approach and level of funding varies considerably among sectors, companies and disciplines. The wide variety of philosophies creates difficulties for those who seek to work with industry. Most funding arrangement are built through extensive engagement, opportunities to leverage funds particularly in higher risk or less well defined areas (e.g., geoscience), and the attraction of meeting potential new high quality employees. Barriers to funding include unrealistic perceptions of confidentiality issues in industry, bureaucracy and unrealistic IP constraints in academia, and onerous overhead charges by universities that vastly exceed those charged by consulting and contract researchers. Academics and students can benefit immensely from productive research arrangements with industry, but understanding realistic expectations on both sides is critical. Although funding from industry may introduce constraints, some companies are willing to take a virtual hands-off approach in support of quality science. Selecting the appropriate researchers and methodology is important; it takes time for students to become effective and some problems are simply not suited to graduate research, or even academia. Some Governments play an enormous role in facilitating collaborative research with industry while others struggle to differentiate programs that encourage investment from those that unfairly subsidize industry. The traditional Government role

  7. Social media in the healthcare context: Ethical challenges and ...

    African Journals Online (AJOL)

    The internet may also provide opportunities for patient education through peerreviewed websites and to build professional networks. Institutions should have policies on the uses of social media. Emerging technology will continue to change the landscape of social media and social networking and the way patients and ...

  8. Communication in Healthcare: Opportunities for information technology and concerns for patient safety

    NARCIS (Netherlands)

    H. Pirnejad (Habibollah)

    2008-01-01

    textabstractUnderstanding healthcare workflow is fundamental for design and implementation of information systems. Communication and information exchange between healthcare professionals plays a pivotal role in developing smooth workflow within and between healthcare organizations. The study in this

  9. Reflections on the Opportunities and Challenges of Disaster Response

    Science.gov (United States)

    Juntunen, Cindy L.

    2011-01-01

    This reaction article applauds the authors of the Major Contribution for their thoughtful and thorough consideration of the myriad issues that accompany disaster mental health work. The reaction highlights three themes that emerged in the articles of the contribution: opportunities for collaboration, opportunities for the application of social…

  10. Challenge or hindrance: Does job stress affect presenteeism among Chinese healthcare workers?

    Science.gov (United States)

    Yang, Tianan; Ma, Mingxu; Zhu, Mingjing; Liu, Yuanling; Chen, Qian; Zhang, Shiyang; Deng, Jianwei

    2018-03-27

    We examined the effects of challenge stress and hindrance stress on general health and presenteeism among Chinese healthcare workers. Structural equation modeling was used to evaluate data from a national hospital survey in China (n = 1392). Job stress, general health, and presenteeism were measured by the Perceived Ability to Work Scale, the 8-item Short-Form Health Survey, and the Challenge- and Hindrance-Related Self-reported Stress Scale. Challenge stress and hindrance stress were significantly positively correlated (β = 0.62, SE = 0.021; p stress was directly negatively associated with presenteeism (β = -0.05, SE = 0.037; p stress was positively associated with presenteeism (β = 0.25, SE = 0.040; p health. Hospital managers should provide healthcare workers with an appropriate level of challenge, but employee health is the most important consideration. Further efforts targeting job stress and health of junior healthcare workers are required.

  11. An integrated drug prescription and distribution system: challenges and opportunities.

    Science.gov (United States)

    Lanssiers, R; Everaert, E; De Win, M; Van De Velde, R; De Clercq, H

    2002-01-01

    Using the hospital's drug prescription and distribution system as a guide, benefits and drawbacks of a medical activity management system that is tightly integrated with the supply chain management of a hospital will be discussed from the point of view of various participating healthcare actors.

  12. The Evolving Academic Health Center: Challenges and Opportunities for Psychiatry

    Science.gov (United States)

    Mirin, Steven; Summergrad, Paul

    2011-01-01

    Objective: Regardless of the outcome of current efforts at healthcare reform, the resources that academic health centers need--to provide care for increasingly complex patient populations, support clinical innovation, grow the clinical enterprise, and carry out their research and teaching missions--are in jeopardy. This article examines the value…

  13. Valorisation of post-sorption materials: Opportunities, strategies, and challenges.

    Science.gov (United States)

    Harikishore Kumar Reddy, D; Vijayaraghavan, K; Kim, Jeong Ae; Yun, Yeoung-Sang

    2017-04-01

    Adsorption is a facile, economic, eco-friendly and low-energy requiring technology that aims to separate diverse compounds (ions and molecules) from one phase to another using a wide variety of adsorbent materials. To date, this technology has been used most often for removal/recovery of pollutants from aqueous solutions; however, emerging post-sorption technologies are now enabling the manufacture of value-added key adsorption products that can subsequently be used for (i) fertilizers, (ii) catalysis, (iii) carbonaceous metal nanoparticle synthesis, (iv) feed additives, and (v) biologically active compounds. These new strategies ensure the sustainable valorisation of post-sorption materials as an economically viable alternative to the engineering of other green chemical products because of the ecological affability, biocompatibility, and widespread accessibility of post-sorption materials. Fertilizers and feed additives manufactured using sorption technology contain elements such as N, P, Cu, Mn, and Zn, which improve soil fertility and provide essential nutrients to animals and humans. This green and effective approach to managing post-sorption materials is an important step in reaching the global goals of sustainability and healthy human nutrition. Post-sorbents have also been utilized for the harvesting of metal nanoparticles via modern catalytic pyrolysis techniques. The resulting materials exhibited a high surface area (>1000m 2 /g) and are further used as catalysts and adsorbents. Together with the above possibilities, energy production from post-sorbents is under exploration. Many of the vital 3E (energy, environment, and economy) problems can be addressed using post-sorption materials. In this review, we summarize a new generation of applications of post-adsorbents as value-added green chemical products. At the end of each section, scientific challenges, further opportunities, and issues related to toxicity are discussed. We believe this critical

  14. Digital Technology and Mental Health Interventions: Opportunities and Challenges

    Directory of Open Access Journals (Sweden)

    Aguilera, Adrian

    2015-02-01

    Full Text Available The growth of the Internet, mobile phones, social media and other digital technologies has changed our world in many ways. It has provided individuals with information that was previously only available to a select few. An example of the reach of technology is data that as of October 2012, there are over 6 billion phones worldwide (BBC, 2012. The availability of data in real time has presented hopes of intervening more efficiently and managing health problems by leveraging limited human resources. It also has an impact in changing the roles of providers and patients and in legal and ethical issues including privacy in digital health interactions. This paper will discuss why digital technology has received recent attention in the area of mental health, present some applications of technology for mental health to date, explore the challenges to full implementation in clinical settings, and present future opportunities for digital technologies.El crecimiento del Internet, los teléfonos móviles, las redes sociales y otras tecnologías digitales ha cambiado nuestro mundo de muchas maneras. Ha proporcionado a las personas con la información que antes sólo estaba disponible para un grupo selecto, por ejemplo a partir de octubre de 2012. Un ejemplo del alcance de la tecnología son los datos que dicen que hay más de 6 millones de teléfonos en todo el mundo (BBC, 2012. La disponibilidad de los datos en tiempo real a presentado la esperanza de intervenir de manera más eficiente y manejar los problemas de salud los recursos humanos limitados. También tiene un impacto en el cambio de los roles de los proveedores y los pacientes y en aspectos legales y éticos, incluyendo la privacidad en las interacciones de salud digital. Este artículo discutirá unas razones por cual la tecnología digital ha recibido atención recientemente en el área de salud mental, presentará algunas aplicaciones de la tecnología para mejorar la salud mental hasta la fecha

  15. Challenges and Opportunities in Geocuration for Disaster Response

    Science.gov (United States)

    Molthan, A.; Burks, J. E.; McGrath, K.; Ramachandran, R.; Goodman, H. M.

    2015-12-01

    . The authors will review some activities related to recent data acquisitions for severe weather events and the 2015 Nepal Earthquake, discuss challenges and opportunities for geocuration, and suggest means of improving the management of data and scientific collaboration if applied to future events.

  16. Game based learning for 21st century transferable skills: challenges and opportunities

    NARCIS (Netherlands)

    Bellotti, Francesco; Bottino, Rosa Maria; Nadolski, Rob; Fernández Manjón, Baltasar

    2012-01-01

    Bellotti, F., Bottino, R. M., Nadolski, R. J., & Fernández Manjón, B. (2012, 4-6 July). Game based learning for 21st century transferable skills: challenges and opportunities. Presentation at the Workshop Game based learning for 21st century transferable skills: challenges and opportunities, 12th

  17. Challenges of the New Zealand healthcare disaster preparedness prior to the Canterbury earthquakes: a qualitative analysis.

    Science.gov (United States)

    Al-Shaqsi, Sultan; Gauld, Robin; Lovell, Sarah; McBride, David; Al-Kashmiri, Ammar; Al-Harthy, Abdullah

    2013-03-15

    Disasters are a growing global phenomenon. New Zealand has suffered several major disasters in recent times. The state of healthcare disaster preparedness in New Zealand prior to the Canterbury earthquakes is not well documented. To investigate the challenges of the New Zealand healthcare disaster preparedness prior to the Canterbury earthquakes. Semi-structured interviews with emergency planners in all the District Health Boards (DHBs) in New Zealand in the period between January and March 2010. The interview protocol revolved around the domains of emergency planning adopted by the World Health Organization. Seventeen interviews were conducted. The main themes included disinterest of clinical personnel in emergency planning, the need for communication backup, the integration of private services in disaster preparedness, the value of volunteers, the requirement for regular disaster training, and the need to enhance surge capability of the New Zealand healthcare system to respond to disasters. Prior to the Canterbury earthquakes, healthcare disaster preparedness faced multiple challenges. Despite these challenges, New Zealand's healthcare response was adequate. Future preparedness has to consider the lessons learnt from the 2011 earthquakes to improve healthcare disaster planning in New Zealand.

  18. Emergence of 3D Printed Dosage Forms: Opportunities and Challenges

    OpenAIRE

    Albed Alhnan, Mohamed; Okwuosa, Tochukwu; Sadia, Muzna; Wan, Ka-Wai; Ahmed, Waqar; Arafat, Basel

    2016-01-01

    The recent introduction of the first FDA approved 3D-printed drug has fuelled interest in 3D printing technology, which is set to revolutionize healthcare. Since its initial use, this rapid prototyping (RP) technology has evolved to such as extent that it is currently being used in a wide range of applications including in tissue engineering, dentistry, construction, automotive and aerospace. However, in the pharmaceutical industry this technology is still in its infancy and its potential yet...

  19. Oral healthcare challenges for older Punjabi-speaking immigrants.

    Science.gov (United States)

    MacEntee, Michael I; Wong, Sabrina T; Smith, André; Beattie, B Lynn; Brondani, Mario; Bryant, S Ross; Graf, Peter; Soheilipour, Shimae

    2014-06-01

    This study explored how older Punjabi-speaking South-Asian immigrants (four focus groups; 33 participants) in Surrey, British Columbia, perceive oral health and related problems. Content analysis revealed two umbrella themes: (a) interpretations of mouth conditions and (b) challenges to oral health. The umbrella themes had four sub-themes: damage caused by heat (wai), disturbances caused by caries, coping with dentures, and quality of life. Three challenges were considered: home remedies, Western dentistry, and difficulties accessing dentists. Participants explained oral diseases in terms of a systemic infection (resha), and preferred to decrease imbalances of wai in the mouth with home remedies from India. We conclude that older Punjabi-speaking immigrants interpret oral health and disease in the context of both Western and Ayurvedic traditions, and that they manage dental problems with a mix of traditional remedies supplemented, if possible, by elective oral health care in India, and by emergency dental care in Canada.

  20. Open Innovation Challenge in Healthcare. Role for Education.

    Science.gov (United States)

    Dimitriu, Rodica; Lungeanu, Diana; Mãnescu, Cristina; Pantazi, Mirela; Mihalas, George I

    2015-01-01

    The vision of this paper is that collaboration creates new openings for engagement of non-commercial actors, such as universities, in innovation networks on the one hand, while opening up for collaborative innovation, and getting valuable real life anchors on the other hand, all these underpinned by greater connectivity and globalization. We present our approach in re-designing the courses on medical informatics and data processing to meet these challenges by employing public Internet services and media facilitation.

  1. Online Learning: Addressing Challenges and Seizing Opportunities. Hawaii

    Science.gov (United States)

    Alliance for Excellent Education, 2010

    2010-01-01

    America's K-12 education system faces three significant challenges: (1) increased global demands for skilled workers, (2) significant financial shortfalls, and (3) a looming teacher shortage. Independently, these factors present significant challenges for U.S. schools. In combination, they create a national imperative for swift action to create a…

  2. Online Learning: Addressing Challenges and Seizing Opportunities. South Dakota

    Science.gov (United States)

    Alliance for Excellent Education, 2010

    2010-01-01

    America's K-12 education system faces three significant challenges: (1) increased global demands for skilled workers, (2) significant financial shortfalls, and (3) a looming teacher shortage. Independently, these factors present significant challenges for U.S. schools. In combination, they create a national imperative for swift action to create a…

  3. Online Learning: Addressing Challenges and Seizing Opportunities. North Dakota

    Science.gov (United States)

    Alliance for Excellent Education, 2010

    2010-01-01

    America's K-12 education system faces three significant challenges: (1) increased global demands for skilled workers, (2) significant financial shortfalls, and (3) a looming teacher shortage. Independently, these factors present significant challenges for U.S. schools. In combination, they create a national imperative for swift action to create a…

  4. Tertiary Education in the 21st Century: Challenges and Opportunities.

    Science.gov (United States)

    Salmi, Jamil

    2001-01-01

    Examines new challenges characterizing the environment in which higher education institutions operate and compete. Explores concrete implications of these challenges in terms of changing institutional forms and new ways of delivering higher education programs, looking at promising trends and experiences in countries and institutions which have…

  5. The Google Online Marketing Challenge and Research Opportunities

    Science.gov (United States)

    Neale, Larry; Treiblmaier, Horst; Henderson, Vani; Hunter, Lee; Hudson, Karen; Murphy, Jamie

    2009-01-01

    The Google Online Marketing Challenge is an ongoing collaboration between Google and academics, to give students experiential learning. The Challenge gives student teams US$200 in AdWords, Google's flagship advertising product, to develop online marketing campaigns for actual businesses. The end result is an engaging in-class exercise that…

  6. WE-AB-213-03: Challenges and Opportunities

    International Nuclear Information System (INIS)

    Borras, C.

    2015-01-01

    recruitment of professionals with incomplete education. In most LA countries only one MP responsible for each Center is currently mandated. Currently there is a large disparity among MP training programs and there is significant debate about the standards of MP graduate education in many LA countries. There are no commonly recognized academic programs, not enough clinical training sites and clinical training is not typically considered as part of the MP work. Economic pressures and high workloads also impede the creation of more training centers. The increasing need of qualified MPs require establishing a coordinated system of national Education & Training Centers (ETC), to meet the international standards of education and training in Medical Physics. This shortfall calls for support of organizations such as the IOMP, AAPM, ALFIM, IAEA, etc. Examples from various LA countries, as well as some proposed solutions, will be presented. In particular, we will discuss the resources that the AAPM and its members can offer to support regional programs. The ‘Medical Imaging’ physicist in the emerging world: Challenges and opportunities - Caridad Borrás (WGNIMP Chair) While the role of radiation therapy physicists in the emerging world is reasonably well established, the role of medical imaging physicists is not. The only perceived needs in radiology departments are equipment quality control and radiation protection, tasks that can be done by a technologist or a service engineer. To change the situation, the International Basic Safety Standard, which is adopted/adapted world-wide as national radiation protection regulations, states: “For diagnostic radiological procedures and image guided interventional procedures, the requirements of these Standards for medical imaging, calibration, dosimetry and quality assurance, including the acceptance and commissioning of medical radiological equipment, are fulfilled by or under the oversight of, or with the documented advice of a medical

  7. WE-AB-213-03: Challenges and Opportunities

    Energy Technology Data Exchange (ETDEWEB)

    Borras, C.

    2015-06-15

    recruitment of professionals with incomplete education. In most LA countries only one MP responsible for each Center is currently mandated. Currently there is a large disparity among MP training programs and there is significant debate about the standards of MP graduate education in many LA countries. There are no commonly recognized academic programs, not enough clinical training sites and clinical training is not typically considered as part of the MP work. Economic pressures and high workloads also impede the creation of more training centers. The increasing need of qualified MPs require establishing a coordinated system of national Education & Training Centers (ETC), to meet the international standards of education and training in Medical Physics. This shortfall calls for support of organizations such as the IOMP, AAPM, ALFIM, IAEA, etc. Examples from various LA countries, as well as some proposed solutions, will be presented. In particular, we will discuss the resources that the AAPM and its members can offer to support regional programs. The ‘Medical Imaging’ physicist in the emerging world: Challenges and opportunities - Caridad Borrás (WGNIMP Chair) While the role of radiation therapy physicists in the emerging world is reasonably well established, the role of medical imaging physicists is not. The only perceived needs in radiology departments are equipment quality control and radiation protection, tasks that can be done by a technologist or a service engineer. To change the situation, the International Basic Safety Standard, which is adopted/adapted world-wide as national radiation protection regulations, states: “For diagnostic radiological procedures and image guided interventional procedures, the requirements of these Standards for medical imaging, calibration, dosimetry and quality assurance, including the acceptance and commissioning of medical radiological equipment, are fulfilled by or under the oversight of, or with the documented advice of a medical

  8. Performance Evaluation and Accountability for School Psychologists: Challenges and Opportunities

    Science.gov (United States)

    Morrison, Julie Q.

    2013-01-01

    The call for school psychologists to demonstrate accountability in the evaluation of services at the individual, group, and system levels comes at a time when school districts nationally are pursuing personnel evaluation models that link teachers' instructional practices to student achievement. School psychologists have an opportunity to take a…

  9. Opportunities and Challenges for Initial Implementation of Solutions Journalism Coursework

    Science.gov (United States)

    Thier, Kathryn

    2016-01-01

    As journalism schools continue to respond to industry disruption, some are adding curricula about practices that reframe traditional journalism. In this article, I examined experiences of some of the first university instructors of solutions journalism--critical reporting on responses to social problems--to explore the opportunities and challenges…

  10. Military Suicide Research Consortium: Extension to New Opportunities and Challenges

    Science.gov (United States)

    2017-04-01

    such as toolkits , policy recommendations, or training plans. Subtask 4: Determine gaps in implementation science research and methods relevant to...Major Task 9: Continue pre-doctoral and postdoctoral training experiences at FSU and Rocky Mountain MIRECC Subtask 1: Establish career development...The following milestone was achieved in Year 1:  Career development and training experiences established. What opportunities for training

  11. OBOR opportunities and challenges for the Dutch Agribusiness Sector

    NARCIS (Netherlands)

    Zhang, Xiaoyong

    2016-01-01

    The Netherlands is the second largest exporter of Agriproducts in the world.
    However, its export volume to China is insignificant. The ‘One Belt One Road’
    initiative (OBOR) provides a great opportunity to increase the volume. But this
    will not be achieved easily. It requires a vision and

  12. The New WTO Telecom Agreement: Opportunities and Challenges.

    Science.gov (United States)

    Sisson, Peter

    1997-01-01

    The telecommunication agreement reached by the World Trade Organization (WTO) in 1997 will accelerate the global trend toward increased market access, competition, and deregulation. Examines opportunities for marketing and operations, dispute resolution and enforcement, profitability, and the exclusion of Russia and China. Includes the WTO…

  13. Healthcare Hackathons Provide Educational and Innovation Opportunities: A Case Study and Best Practice Recommendations

    OpenAIRE

    Silver, Julie K.; Binder, David S.; Zubcevik, Nevena; Zafonte, Ross D.

    2016-01-01

    Physicians and other healthcare professionals are often the end users of medical innovation; however, they are rarely involved in the beginning design stages. This often results in ineffective healthcare solutions with poor adoption rates. At the early design stage, innovation would benefit from input from healthcare professionals. This report describes the first-ever rehabilitation hackathon?an interdisciplinary and competitive team event aimed at accelerating and improving healthcare soluti...

  14. Trends and Challenges in Smart Healthcare Research: A Journey from Data to Wisdom

    Energy Technology Data Exchange (ETDEWEB)

    Solanas, Agusti; Fran, Casino; Batista, Edgar; Rallo Moya, Roberto J.

    2017-10-12

    Smart Healthcare is a relatively new context-aware healthcare paradigm influenced by several fields of knowledge, namely medical informatics, communications and electronics, bioengineering, ethics and so on. Thus, many challenging problems are related to smart healthcare but in many cases they are explored individually in their respective fields and, as a result, they are not always known by the smart healthcare research community working in more specific domains. The aim of this article is to identify some of the most relevant trends and research lines that are going to affect the smart healthcare field in the years to come. To do so, the article considers a systematic approach that classifies the identified research trends and problems according to their appearance within the data life cycle, this is, from the data gathering in the physical layer (lowest level) until their final use in the application layer (highest level). By identifying and classifying those research trends and challenges, we help to pose questions that the smart healthcare community will need to address. Consequently, we set a common ground to explore important problems in the field, which will have significant impact in the years to come.

  15. Female healthcare managers and the glass ceiling. The obstacles and opportunities for women in management.

    Science.gov (United States)

    Wiggins, C

    1991-01-01

    Despite the large number of women in the healthcare field, healthcare management resembles other industries in its severe lack of women in upper-management positions and in the "glass ceiling" that contributes to this dearth. Although not enough has been specifically written on women healthcare managers, the author reviews what is available, along with some of the general management literature.

  16. Big data : opportunities and challenges in asset management : final report.

    Science.gov (United States)

    2016-08-01

    State Departments of Transportation and other transportation agencies collect vast quantities of data but managing, accessing and sharing data has been problematic and well documented. This project reviewed the similar challenges faced by other indus...

  17. Opportunities and challenges of E-learning in Zambia

    African Journals Online (AJOL)

    1University of Zambia (UNZA), Department of Medical Education, Lusaka, Zambia. 2 LinkNet ... are teacher centred and often limiting students input. .... challenge of measuring their ... developed locally through the College of Surgeons. 13.

  18. Challenges and opportunities for quality seed potato availability and ...

    African Journals Online (AJOL)

    ACSS

    Key words: Quality seed potato, seed system and challenges ... systems, inadequate seed production and ... informal sources of seed potato, despite ..... Directorate General for International. Co-operation (DGIC), Brussels,. Belgium. 1540pp.

  19. Challenges and opportunities in dermal/transdermal delivery

    OpenAIRE

    Paudel, Kalpana S; Milewski, Mikolaj; Swadley, Courtney L; Brogden, Nicole K; Ghosh, Priyanka; Stinchcomb, Audra L

    2010-01-01

    Transdermal drug delivery is an exciting and challenging area. There are numerous transdermal delivery systems currently available on the market. However, the transdermal market still remains limited to a narrow range of drugs. Further advances in transdermal delivery depend on the ability to overcome the challenges faced regarding the permeation and skin irritation of the drug molecules. Emergence of novel techniques for skin permeation enhancement and development of methods to lessen skin i...

  20. Security in Visible Light Communication: Novel Challenges and Opportunities

    Directory of Open Access Journals (Sweden)

    Christian ROHNER

    2015-09-01

    Full Text Available As LED lighting becomes increasingly ubiquitous, Visible Light Communication is attracting the interest of academia and industry as a complement to RF as the physical layer for the Internet of Things. Aside from its much greater spectral availability compared to RF, visible light has several attractive properties that may promote its uptake: its lack of health risks, its opportunities for spatial reuse, its relative immunity to multipath fading, its lack of electromagnetic interference, and its inherently secure nature: differently from RF, light does not penetrate through walls. In this paper, we outline the security implications of Visible Light Communication, review the existing contributions to this under-explored space, and survey the research opportunities that we envision for the near future.

  1. Opportunities and challenges for a sustainable energy future.

    Science.gov (United States)

    Chu, Steven; Majumdar, Arun

    2012-08-16

    Access to clean, affordable and reliable energy has been a cornerstone of the world's increasing prosperity and economic growth since the beginning of the industrial revolution. Our use of energy in the twenty-first century must also be sustainable. Solar and water-based energy generation, and engineering of microbes to produce biofuels are a few examples of the alternatives. This Perspective puts these opportunities into a larger context by relating them to a number of aspects in the transportation and electricity generation sectors. It also provides a snapshot of the current energy landscape and discusses several research and development opportunities and pathways that could lead to a prosperous, sustainable and secure energy future for the world.

  2. Healthcare

    Science.gov (United States)

    Carnevale, Anthony P.; Smith, Nicole; Gulish, Artem; Beach, Bennett H.

    2012-01-01

    This report, provides detailed analyses and projections of occupations in healthcare fields, and wages earned. In addition, the important skills and work values associated with workers in those fields of healthcare are discussed. Finally, the authors analyze the implications of research findings for the racial, ethnic, and class diversity of the…

  3. New challenges of public health: bringing the future of personalised healthcare into focus.

    Science.gov (United States)

    Ricciardi, Walter; Boccia, Stefania

    2017-10-01

    The greater personalization of healthcare represents a driver of innovation for research, and for the healthcare systems and industries as a whole. Still policy-makers, healthcare professionals, citizens and private companies need to take some steps to realize the potential for such a radical shift. In this paper, we illustrate the challenges, the benefits and consequences that might accompany the implementation of personalized healthcare, and the steps that policy-makers and practitioners would need to take to realise its potential. Six main prerequisites for radical change in healthcare are presented, that include achieving better genetic literacy for professionals and for the public; engaging citizen in the discourse; improved governance, consent and trust in healthcare; feeding and harnessing the data-knowledge cycle for better health; adopting and adapting the Health Technology Assessment framework for the evaluation of the new technologies; and retaining humanity and community in health and care. Some of these concepts originate from a discussion on the future of health and healthcare, looking at least 15-20 years into the future, that we had at the end of 2016 at Ickworth with an international group of experts, under the aegis of the PHG Foundation. © The Author 2017. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved.

  4. DEIMOS-1 Announcement of Opportunity: New Challenges and Achievements

    Science.gov (United States)

    Casanova, J.-L.; Duque, P.; Calle, A.; Romo, A.; Sanz, J.; Bello, M.

    2010-12-01

    This paper will show the projects and results obtained as consequence of the Deimos-1 Announcement of Opportunity, AO, offered by the Spanish company Deimos Imaging, owner and manager of the first commercial Spanish satellite dedicated to Earth Observation: Deimos-1. The satellite Deimos-1 belongs to the DMC (Disaster Managing Constellation) and it was launched on July, 2009, by means of a Dnepr rocket, from the Russian cosmodrome of Baikonur.

  5. Opportunities and challenges within urban health and sustainable development

    DEFF Research Database (Denmark)

    Fisher, Jack E.; Andersen, Zorana J.; Loft, Steffen

    2017-01-01

    The United Nations’ Sustainable Development Goals mark aunique window of opportunity for both human and planetaryhealth. With rising life expectancy and rapidly expanding urbanpopulations exposed to pollution and sedentary lifestyles, thereis a greater focus on reducing the gap between life...... expectancyand number of healthy years lived, whilst limiting anthropogenicactivities contributing to pollution and climate change. Thus,urban development and policies, which can create win–winsituations for our planet and human health, falls into the realmand expertise of public health. However, some...

  6. Education and Training in Decommissioning: Needs, Opportunities and Challenges

    International Nuclear Information System (INIS)

    Kockerols, P.; Schneider, H. G.; Freer, M.

    2016-01-01

    Full text: The decommissioning of nuclear facilities is an industrial activity that is growing worldwide, creating job opportunities and requiring skilled workers. European industry has acquired know-how and today Europe can position itself at the top level in the world decommissioning market. However, in view of the expected expansion of the activities, efforts are necessary to share and enhance the underpinning knowledge, skills and competences. In this perspective, the University of Birmingham in association with the European Commission’s Joint Research Centre have organized a joint seminar to address the following questions in relation to education and training in nuclear decommissioning: • What are the competence needs for the future? • What are the education and training opportunities? • How can we stimulate interest and future talent? In answering these questions a report has been issued giving orientations for stimulating the development, coordination and promotion of adequate education and training programmes at EU level in nuclear decommissioning. Following the conclusions of the report the JRC and interested partners have launched the initiative to consolidate existing training programmes in decommissioning, in order to facilitate their promotion and the opportunities they can offer. (author

  7. CO2 exsolution - challenges and opportunities in subsurface flow management

    Science.gov (United States)

    Zuo, Lin; Benson, Sally

    2014-05-01

    for storage security. Falta et al. [2013] show that if carbonated brine migrates upwards and exsolution occurs, brine migration would be greatly reduced and limited by the presence of exsolved CO2 and the consequent low relatively permeability to brine. Similarly, if an exsolved CO2 phase were to evolve in seals, for example, after CO2 injection stops, the effect would be to reduce the permeability to brine and the CO2 would have very low mobility. This flow blocking effect is also studied with water/oil/CO2 [Zuo et al., 2013]. Experiments show that exsolved CO2 performs as a secondary residual phase in porous media that effectively blocks established water flow paths and deviates water to residual oil zones, thereby increasing recovery. Overall, our studies suggest that CO2 exsolution provides an opportunity for mobility control in subsurface processes. However, the lack of simulation capability that accounts for differences between gas injection and gas exsolution creates challenges for modeling and hence, designing studies to exploit the mobility reduction capabilities of CO2 exsolution. Using traditional drainage multiphase flow parameterization in simulations involving exsolution will lead to large errors in transport rates. Development of process dependent parameterizations of multiphase flow properties will be a key next step and will help to unlock the benefits from gas exsolution. ACKNOWLEDGEMENT This work is funded by the Global Climate and Energy Project (GCEP) at Stanford University. This work was also supported by U.S. EPA, Science To Achieve Results (STAR) Program, Grant #: 834383, 2010-2012. REFERENCES Falta, R., L. Zuo and S.M. Benson (2013). Migration of exsolved CO2 following depressurization of saturated brines. Journal of Greenhouse Gas Science and Technology, 3(6), 503-515. Zuo, L., S.C.M. Krevor, R.W. Falta, and S.M. Benson (2012). An experimental study of CO2 exsolution and relative permeability measurements during CO2 saturated water

  8. Immunizations challenge healthcare personnel and affects immunization rates.

    Science.gov (United States)

    Strohfus, Pamela K; Kim, Susan C; Palma, Sara; Duke, Russell A; Remington, Richard; Roberts, Caleb

    2017-02-01

    This study measured 1. medical office immunization rates and 2. health care personnel competency in managing vaccine practices before and after evidence-based immunization education was provided. This descriptive study compared 32 family medicine and pediatric offices and 178 medical assistants, licensed practical nurses, registered nurses, nurse practitioners, and physicians in knowledge-based testing pre-education, post-education, and 12-months post-education. Immunization rates were assessed before and 18-months post-education. Immunization rates increased 10.3% - 18months post-education; knowledge increased 7.8% - 12months post-education. Family medicine offices, licensed practical nurses, and medical assistants showed significant knowledge deficits before and 12-months post-education. All demographic groups scored less in storage/handling 12-months post-education. This study is one of the first studies to identify competency challenges in effective immunization delivery among medical assistants, licensed practical nurses, and family medicine offices. Formal and continuous education in immunization administration and storage/handling is recommended among these select groups. Copyright © 2016 Elsevier Inc. All rights reserved.

  9. Exploiting HPC Platforms for Metagenomics: Challenges and Opportunities (MICW - Metagenomics Informatics Challenges Workshop: 10K Genomes at a Time)

    Energy Technology Data Exchange (ETDEWEB)

    Canon, Shane

    2011-10-12

    DOE JGI's Zhong Wang, chair of the High-performance Computing session, gives a brief introduction before Berkeley Lab's Shane Canon talks about "Exploiting HPC Platforms for Metagenomics: Challenges and Opportunities" at the Metagenomics Informatics Challenges Workshop held at the DOE JGI on October 12-13, 2011.

  10. Sickle Cell Disease: New Opportunities and Challenges in Africa

    Directory of Open Access Journals (Sweden)

    J. Makani

    2013-01-01

    Full Text Available Sickle cell disease (SCD is one of the most common genetic causes of illness and death in the world. This is a review of SCD in Africa, which bears the highest burden of disease. The first section provides an introduction to the molecular basis of SCD and the pathophysiological mechanism of selected clinical events. The second section discusses the epidemiology of the disease (prevalence, morbidity, and mortality, at global level and within Africa. The third section discusses the laboratory diagnosis and management of SCD, emphasizing strategies that been have proven to be effective in areas with limited resources. Throughout the review, specific activities that require evidence to guide healthcare in Africa, as well as strategic areas for further research, will be highlighted.

  11. Youth substance use prevention interventions: Opportunities and challenges

    Directory of Open Access Journals (Sweden)

    Flavio F. Marsiglia

    2016-12-01

    Full Text Available The United Nations estimates that 1 in 20 adults, or a quarter of a billion people between the ages of 15 and 64 years, used at least one illicit drug in 2014, this number does not include tobacco and alcohol (UNODC, 2016. During the same year, more than 22 million Americans aged 12 and older self-reported needing treatment for alcohol or illicit drug use (SAMHA, 2016. Annually, drug abuse and addiction cost the USA society more than 200 billion US dollars in the healthcare, criminal justice, and legal systems, and in lost workplace production/participation (Office on National Drug Control Policy, 2011. The rippling social and health effects of abusing alcohol and other drugs not only negatively impact the individual users but their families, communities and society at large.

  12. The complexity of collaboration: Opportunities and challenges in contracted research

    Directory of Open Access Journals (Sweden)

    Marion Bowl

    2010-11-01

    Full Text Available This article explores some of the challenges of utilising collaborative research approaches when undertaking contracted research projects for government and non-government agencies in the adult and community education (ACE sector. To discuss these challenges, the article draws on three recent examples of research projects undertaken for ACE sector organisations in Aotearoa New Zealand. These challenges include managing relationships with the different parties to the research; dealing with conflicting expectations of funding agencies, commissioning organisations and practitioners; and ownership and dissemination of findings. We highlight the complexity of notions of collaboration and the importance of deliberate trust-building in establishing credibility. We also open up for discussion the thorny issues of who owns the right to disseminate research findings and how far should researchers’ and universities’ responsibilities extend to ensure that research findings are put in the public domain?

  13. Challenges and opportunities of open data in ecology.

    Science.gov (United States)

    Reichman, O J; Jones, Matthew B; Schildhauer, Mark P

    2011-02-11

    Ecology is a synthetic discipline benefiting from open access to data from the earth, life, and social sciences. Technological challenges exist, however, due to the dispersed and heterogeneous nature of these data. Standardization of methods and development of robust metadata can increase data access but are not sufficient. Reproducibility of analyses is also important, and executable workflows are addressing this issue by capturing data provenance. Sociological challenges, including inadequate rewards for sharing data, must also be resolved. The establishment of well-curated, federated data repositories will provide a means to preserve data while promoting attribution and acknowledgement of its use.

  14. Bringing nanomedicines to market: regulatory challenges, opportunities, and uncertainties.

    Science.gov (United States)

    Nijhara, Ruchika; Balakrishnan, Krishna

    2006-06-01

    Scientists and entrepreneurs who contemplate developing nanomedicine products face several unique challenges in addition to many of the traditional hurdles of product development. In this review we analyze the major physicochemical, biologic and functional characteristics of several nanomedicine products on the market and explore the question of what made them unique. What made them successful? We also focus on the regulatory challenges faced by nanomedicine product developers. Based on these analyses, we propose the factors that are most likely to contribute to the success of nanomedicine products.

  15. Modeling bladder cancer in mice: opportunities and challenges

    Science.gov (United States)

    Kobayashi, Takashi; Owczarek, Tomasz B.; McKiernan, James M.; Abate-Shen, Cory

    2015-01-01

    The prognosis and treatment of bladder cancer have hardly improved in the last 20 years. Bladder cancer remains a debilitating and often fatal disease, and among the most costly cancers to treat. The generation of informative mouse models has the potential to improve our understanding of bladder cancer progression, as well as impact its diagnosis and treatment. However, relatively few mouse models of bladder cancer have been described and particularly few that develop invasive cancer phenotypes. This review focuses on opportunities for improving the landscape of mouse models of bladder cancer. PMID:25533675

  16. Ethical challenges within Veterans Administration healthcare facilities: perspectives of managers, clinicians, patients, and ethics committee chairpersons.

    Science.gov (United States)

    Foglia, Mary Beth; Pearlman, Robert A; Bottrell, Melissa; Altemose, Jane K; Fox, Ellen

    2009-04-01

    To promote ethical practices, healthcare managers must understand the ethical challenges encountered by key stakeholders. To characterize ethical challenges in Veterans Administration (VA) facilities from the perspectives of managers, clinicians, patients, and ethics consultants. We conducted focus groups with patients (n = 32) and managers (n = 38); semi-structured interviews with managers (n = 31), clinicians (n = 55), and ethics committee chairpersons (n = 21). Data were analyzed using content analysis. Managers reported that the greatest ethical challenge was fairly distributing resources across programs and services, whereas clinicians identified the effect of resource constraints on patient care. Ethics committee chairpersons identified end-of-life care as the greatest ethical challenge, whereas patients identified obtaining fair, respectful, and caring treatment. Perspectives on ethical challenges varied depending on the respondent's role. Understanding these differences can help managers take practical steps to address these challenges. Further, ethics committees seemingly, are not addressing the range of ethical challenges within their institutions.

  17. Implementing Active Learning Reform in the Maldives: Challenges and Opportunities

    Science.gov (United States)

    Di Biase, Rhonda

    2009-01-01

    Many countries are adopting child-centered active learning reforms as they strive to improve the quality of primary education. Consistent challenges can be found in the implementation of similar, global reforms. These issues are discussed here within the following framework: the cultural appropriateness of such reforms; the extent to which active…

  18. Online Learner Engagement: Opportunities and Challenges with Using Data Analytics

    Science.gov (United States)

    Bodily, Robert; Graham, Charles R.; Bush, Michael D.

    2017-01-01

    This article describes the crossroads between learning analytics and learner engagement. The authors do this by describing specific challenges of using analytics to support student engagement from three distinct perspectives: pedagogical considerations, technological issues, and interface design concerns. While engaging online learners presents a…

  19. Challenges and Opportunities Facing Technology Education in Taiwan

    Science.gov (United States)

    Lee, Lung-Sheng Steven

    2009-01-01

    The technology education in Taiwan is prescribed in the national curriculum and provided to all students in grades 1-12. However, it faces the following challenges: (1) Lack of worthy image, (2) Inadequate teachers in elementary schools, (3) Deficient teaching vitality in secondary schools, and (4) Diluted technology teacher education programs. In…

  20. Policy Challenges and Opportunities for Rural Special Education

    Science.gov (United States)

    Rude, Harvey; Miller, Kevin J.

    2018-01-01

    This article reviews current developments in state and national policies that affect rural special education. A brief overview of the federal role in rural education is provided, with emphasis on the implications for the provision of special education services in rural communities. A variety of challenges are identified, including (a) the variable…

  1. The Rural Obstetric Workforce in US Hospitals: Challenges and Opportunities

    Science.gov (United States)

    Kozhimannil, Katy B.; Casey, Michelle M.; Hung, Peiyin; Han, Xinxin; Prasad, Shailendra; Moscovice, Ira S.

    2015-01-01

    Purpose The purpose of this study was to describe the types and combinations of clinicians who are delivering babies in rural hospitals, their employment status, the relationship between hospital birth volume and staffing models, and the staffing challenges faced by rural hospitals. Methods We conducted a telephone survey of 306 rural hospitals in 9 states: Colorado, Iowa, Kentucky, New York, North Carolina, Oregon, Vermont, Washington, and Wisconsin, from November 2013-March 2014 to assess their obstetric workforce. Bivariate associations between hospitals’ annual birth volume and obstetric workforce characteristics were examined, as well as qualitative analysis of workforce changes and staffing challenges. Findings Hospitals with lower birth volume (< 240 births per year) are more likely to have family physicians and general surgeons attending deliveries, while those with a higher birth volume more frequently have obstetricians and midwives attending deliveries. Reported staffing challenges include scheduling, training, census fluctuation, recruitment and retention, and intra-hospital relationships. Conclusions Individual hospitals working in isolation may struggle to address staffing challenges. Federal and state policy makers, regional collaboratives, and health care delivery systems can facilitate solutions through programs such as telehealth, simulation training, and interprofessional education. PMID:25808202

  2. Faculty and Career Advising: Challenges, Opportunities, and Outcome Assessment

    Science.gov (United States)

    Vespia, Kristin M.; Freis, Stephanie D.; Arrowood, Rebecca M.

    2018-01-01

    Psychology prioritizes students' professional or career development by including it as one of the five undergraduate learning goals. Faculty advisors are critical to that development but likely feel less prepared for the role. Departments face challenges assessing associated student learning outcomes. We introduce an instrument programs can use to…

  3. Functional Inkjet Printing on Textiles : Challenges and Opportunities

    NARCIS (Netherlands)

    Agrawal, P. (Pramod); Brinks, G.J. (Ger); Gooijer, H. (Henk)

    2012-01-01

    The main challenge for the Dutch and European textile and clothing sector is to make a paradigm shift from labour intensive industry to knowledge based industry. This shift is essential for gaining a competitive edge and to develop innovative products and eco-friendly processes. A promising

  4. Rural Marketing in India –Challenges, Opportunities and Strategies

    OpenAIRE

    Abhisek Kumar Tripathi

    2012-01-01

    The rural market in Indian economy can be classified under two broad categories. These are the market for consumer goods that comprise of both durable and non-durable goods and the market for agricultural inputs that include fertilizers, pesticides, seeds Key words: rural marketing, marketing, challenges in rural marketing, rural marketing environment

  5. Inclusive Education in Higher Education: Challenges and Opportunities

    Science.gov (United States)

    Moriña, Anabel

    2017-01-01

    Implementing the principles of inclusive education within higher education can be challenging. Inclusive education was originally developed for younger students, prior to its application within higher education. However, as more students with disabilities successfully complete their early schooling, the need to move towards inclusive practices…

  6. Pumped Storage Power plants, Challenges and opportunities - Some conclusions

    International Nuclear Information System (INIS)

    Viollet, Pierre-Louis; Roult, Didier; Mathex, Bruno; Ouaabi, Aziz; Louis, Frederic; Petitjean, Alain; Capuozzo, Vincent; Mazzouji, Farid; Prestat, Bruno; Nekrassov, Andrei; Caignaert, Guy; Vidil, Roland; Guilbaud, Claude; Metais, Olivier

    2011-11-01

    This document briefly synthesizes a conference which addressed the development of pumped storage power plants in the world, and social, economic, technical and scientific challenges related to this development which is closely related to the development of intermittent renewable energies (wind and solar energy). Current developments in different countries (Germany, Portugal, Switzerland, Norway, France and China) are evoked

  7. The Opportunities and Challenges of Research Partnerships in Teacher Education

    Science.gov (United States)

    Schuck, Sandy

    2013-01-01

    Collaborative research partnerships are widely recognised as being of value. This paper examines the benefits, constraints and challenges of research partnerships between teacher education faculties in universities and teacher employing authorities or departments of education and schooling. A case study of a collaborative research partnership…

  8. Assessment of the Impact of Oil: Opportunities and Challenges for ...

    African Journals Online (AJOL)

    heavy dependence on oil presents challenges to policy makers, partly because oil is an exhaustible ..... In this section we examine the impact of oil on the Sudanese economy. We first start ... balance of payment, FDI and social development in Sudan. Beginning ..... Therefore the major policy implication from our findings is ...

  9. Borderland Spaces for Learning Partnership: Opportunities, Benefits and Challenges

    Science.gov (United States)

    Hill, Jennifer; Thomas, Greg; Diaz, Anita; Simm, David

    2016-01-01

    This paper uses case studies and secondary literature to critically examine how learning spaces inhabited by geographers might be used productively as borderland spaces for learning partnership. Borderland spaces are novel, challenging, permissive and liminal, destabilizing traditional power hierarchies. In these spaces, students gain confidence…

  10. Education and Training in Decommissioning Needs, Opportunities and Challenges

    International Nuclear Information System (INIS)

    Kockerols, Pierre; Schneider, Hans Guenther; ); Freer, Martin

    2016-01-01

    The decommissioning of nuclear facilities is an industrial activity that is growing worldwide, creating job opportunities at all educational levels. Over the last decades, European companies have been involved in decommissioning projects that are targeted at delivering an environmentally friendly end-product, in line with the 'circular economy', as promoted by EU and national policies. European industry has acquired know-how and today Europe can position itself at the top level in the world decommissioning market. However, in view of the preparation of future decommissioning programmes, efforts are necessary to ensure and share the underpinning knowledge, skills and competences. In this perspective, the University of Birmingham in association with the European Commission's Joint Research Centre have organised a joint seminar to address the following questions in relation to education and training in nuclear decommissioning: - What are the competence needs for the future? - What are the education and training opportunities? - How can we stimulate interest and future talent? In answering these questions a report has been published which provides suggestions for helping the development, coordination and promotion of adequate education and training programmes at EU level in nuclear decommissioning. It highlights, in particular, the necessity to improve the long term planning of the resources and competences, addressing the specifics of decommissioning activities, to give more visibility to the career possibilities in the sector, and to enhance the cooperation between the existing education and training programmes, providing also more clarity in the learning outcomes. (authors)

  11. Using Twitter™ to drive research impact: A discussion of strategies, opportunities and challenges.

    Science.gov (United States)

    Schnitzler, Katy; Davies, Nigel; Ross, Fiona; Harris, Ruth

    2016-07-01

    Researchers have always recognised the importance of disseminating the findings of their work, however, recently the need to proactively plan and drive the impact of those findings on the wider society has become a necessity. Firstly, this is because funders require evidence of return from investment and secondly and crucially because national research assessments are becoming powerful determinants of future funding. In research studies associated with nursing, impact needs to be demonstrated by showing the effect on a range of stakeholders including service users, patients, carers, the nursing workforce and commissioners. Engaging these groups is a well-known challenge influenced by lack of access to academic journals, lack of time to read long complex research papers and lack of opportunities to interact directly with the researchers. This needs to be addressed urgently to enable nursing research to increase the impact that it has on health delivery and the work of clinical practitioners. Social media is potentially a novel way of enabling research teams to both communicate about research as studies progress and to disseminate findings and research funders are increasingly using it to publicise information about research programmes and studies they fund. A search of the healthcare literature reveals that advice and guidance on the use of social media for research studies is not well understood or exploited by the research community. This paper, therefore, explores how using social networking platforms, notably Twitter™ offers potential new ways for communicating research findings, accessing diverse and traditionally hard-to-reach audiences, knowledge exchange at an exponential rate, and enabling new means of capturing and demonstrating research impact. The paper discusses approaches to initiate the setup of social networking platforms in research projects and considers the practical challenges of using Twitter™ in nursing and healthcare research. The

  12. Clinical practice in community medicine: Challenges and opportunities

    Directory of Open Access Journals (Sweden)

    Rajesh Kumar

    2017-01-01

    Full Text Available Clinical practice with community health perspective makes community medicine a unique specialty. In their health centers, community physicians not only implement disease prevention programs, assess community health needs, manage healthcare teams and advocate for health promoting policies but also diagnose and treat diseases. However, participation of community medicine faculty in the delivery of clinical care varies from place to place due to administrative constraints. Health centers attached with medical college are not dependent on community medicine faculty for clinical service as these centers have their own medical and paramedical staff; whereas, other clinical departments in medical colleges depend on their faculty for delivery of clinical care in the hospital. Consequently, a perception is gaining ground that community medicine is a para-clinical specialty. Strategies for a fixed tenured rotation of faculty in the health centers should be evolved. All faculty members of community medicine must also provide clinical care in the health centers and the quantum of clinical services provided by each one of them should be reported widely to all stakeholders. Community medicine residency programs must ensure that trainee community physicians acquire competency to deliver comprehensive primary health care (promotive, preventive, curative, and rehabilitative in a health center.

  13. Psychiatric education in the correctional setting: challenges and opportunities.

    Science.gov (United States)

    Holoyda, Brian J; Scott, Charles L

    2017-02-01

    As the need for mental healthcare services within correctional settings in the US increases, so does the need for a mental health workforce that is motivated to work within such systems. One potentially effective method by which to increase the number of psychiatrists working in jails, prisons, and parole clinics is to provide exposure to these environments during their training. Correctional settings can serve as unique training sites for medical students and psychiatric residents and fellows. Such training experiences can provide a host of benefits to both trainees and staff within the correctional mental health system. Alongside many potential benefits exist substantial potential barriers to coordinating correctional training experiences, including both programme directors' and residents' concerns regarding safety and enjoyment and negative perceptions of inmate and prisoner patients. The establishment of academic affiliations with correctional institutions and didactic instruction on commonly encountered clinical issues with inmate populations may be methods of diffusing these concerns. Improving residents' and fellows' training experiences offers a hope for increasing the attractiveness of a career in correctional psychiatry.

  14. Challenges and opportunities in dermal/transdermal delivery

    Science.gov (United States)

    Paudel, Kalpana S; Milewski, Mikolaj; Swadley, Courtney L; Brogden, Nicole K; Ghosh, Priyanka; Stinchcomb, Audra L

    2010-01-01

    Transdermal drug delivery is an exciting and challenging area. There are numerous transdermal delivery systems currently available on the market. However, the transdermal market still remains limited to a narrow range of drugs. Further advances in transdermal delivery depend on the ability to overcome the challenges faced regarding the permeation and skin irritation of the drug molecules. Emergence of novel techniques for skin permeation enhancement and development of methods to lessen skin irritation would widen the transdermal market for hydrophilic compounds, macromolecules and conventional drugs for new therapeutic indications. As evident from the ongoing clinical trials of a wide variety of drugs for various clinical conditions, there is a great future for transdermal delivery of drugs. PMID:21132122

  15. Challenges and Opportunities for Research on Same-Sex Relationships

    Science.gov (United States)

    Umberson, Debra; Thomeer, Mieke Beth; Kroeger, Rhiannon A.; Lodge, Amy Caroline; Xu, Minle

    2014-01-01

    Research on same-sex relationships has informed policy debates and legal decisions that greatly affect American families, yet the data and methods available to scholars studying same-sex relationships have been limited. In this article the authors review current approaches to studying same-sex relationships and significant challenges for this research. After exploring how researchers have dealt with these challenges in prior studies, the authors discuss promising strategies and methods to advance future research on same-sex relationships, with particular attention given to gendered contexts and dyadic research designs, quasi-experimental designs, and a relationship biography approach. Innovation and advances in the study of same-sex relationships will further theoretical and empirical knowledge in family studies more broadly and increase understanding of different-sex as well as same-sex relationships. PMID:25598552

  16. Buffer Sizing in Wireless Networks: Challenges, Solutions, and Opportunities

    KAUST Repository

    Showail, Ahmad

    2016-04-01

    Buffer sizing is an important network configuration parameter that impacts the Quality of Service (QoS) characteristics of data traffic. With falling memory costs and the fallacy that \\'more is better\\', network devices are being overprovisioned with large bu ers. This may increase queueing delays experienced by a packet and subsequently impact stability of core protocols such as TCP. The problem has been studied extensively for wired networks. However, there is little work addressing the unique challenges of wireless environment such as time-varying channel capacity, variable packet inter-service time, and packet aggregation, among others. In this paper we discuss these challenges, classify the current state-of-the-art solutions, discuss their limitations, and provide directions for future research in the area.

  17. Reducing Weight for Transportation Applications: Technology Challenges and Opportunities

    Science.gov (United States)

    Taub, Alan I.

    Today's land, sea and air transportation industries — as a business necessity — are focused on technology solutions that will make vehicles more sustainable in terms of energy, the environment, safety and affordability. Reducing vehicle weight is a key enabler for meeting these challenges as well as increasing payload and improving performance. The potential weight reductions from substituting lightweight metals (advanced high-strength steels, aluminum, magnesium and titanium alloys) are well established. For magnesium castings, weight savings of 60% have been reported [1]. The value of weight reduction depends on the transportation sector and ranges from about 5/kg saved for automobiles to over 500/kg saved for aircraft [2]. The challenge is to optimize the material properties and develop robust, high volume, manufacturing technologies and the associated supply chain to fabricate components and subsystems at the appropriate cost for each application.

  18. Challenges and Opportunities for the Obama Administration in Central Asia

    Science.gov (United States)

    2009-06-01

    Asia. Specifically, the 19th century vision of an integrated network of rail lines connecting the former Soviet and Tsarist empires, Iran, India...rear to Afghanistan. In this fashion we would help Central Asia meet the challenges of ex- tremism, of economic decline due to the global eco- nomic...Callwell ( Victorian England’s leading theorist of small wars) wrote, “theory cannot be accepted as conclusive when practice points the other way.”28

  19. Legal Approaches to Online Arbitration: Opportunities and Challenges in Indonesia

    OpenAIRE

    Fitrianingrum, Agustina; Shahrullah, Rina Shahriyani; Syarief, Elza

    2016-01-01

    Abstract Online arbitration is one of the mechanisms to settle business disputes. Using online arbitration in Indonesia is challenging because the Indonesian arbitration law (Law No.30 of 1999 concerning Arbitration and Alternative Dispute Resolution) does not specifcally deal with online arbitration. This research provides arguments and evidences that the relevant Indonesian national laws support the use of online arbitration. It adopts a normative legal research with a qualitative approa...

  20. Skin Microbiota Workshop: Multidisciplinary Perspectives, Challenges and Opportunities

    Science.gov (United States)

    2014-12-08

    SECURITY CLASSIFICATION OF: This report details the outcome of the 1st Skin Microbiota Workshop, Boulder, CO, held on October 15th-16th 2012. The...Sep-2014 Approved for Public Release; Distribution Unlimited Final Report: Skin Microbiota Workshop: Multidisciplinary Perspectives, Challenges and...Number of Papers published in peer-reviewed journals: Number of Papers published in non peer-reviewed journals: Final Report: Skin Microbiota Workshop

  1. Blockchain for the IoT: Opportunities and Challenges

    OpenAIRE

    Ramachandran, Gowri Sankar; Krishnamachari, Bhaskar

    2018-01-01

    Blockchain technology has been transforming the financial industry and has created a new crypto-economy in the last decade. The foundational concepts such as decentralized trust and distributed ledger are promising for distributed, and large-scale Internet of Things (IoT) applications. However, the applications of Blockchain beyond cryptocurrencies in this domain are few and far between because of the lack of understanding and inherent architectural challenges. In this paper, we describe the ...

  2. The Fourth Wave of Digitalization and Public Transport: Opportunities and Challenges

    Directory of Open Access Journals (Sweden)

    Paul Davidsson

    2016-11-01

    Full Text Available We investigate the opportunities and challenges of the forth wave of digitalization, also referred to as the Internet of Things (IoT, with respect to public transport and how it can support sustainable development of society. Environmental, economical, and social perspectives are considered through analysis of the existing literature and explorative studies. We conclude that there are great opportunities for both transport operators and planners, as well as for the travelers. We describe and analyze a number of concrete opportunities for each of these actors. However, in order to realize these opportunities, there are also a number of challenges that needs to be addressed. There are both technical challenges, such as data collection issues, interoperability, scalability and information security, and non-technical challenges such as business models, usability, privacy issues, and deployment.

  3. A short narrative - Challenges and opportunities in expanding research in the Middle East, North Afr

    Science.gov (United States)

    CGH CRTA, Hedieh Mehrtash interviews CGH's Dr. Marie Ricciardone who works with a network of partners in the Middle East and North Africa region, on experiences, challenges, and opportunities in the region.

  4. Prospects, achievements, challenges and opportunities for scaling-up malaria chemoprevention in pregnancy in Tanzania

    DEFF Research Database (Denmark)

    Mubyazi, Godfrey M.; Bygbjerg, Ib Christian; Magnussen, Pascal

    2008-01-01

    To describe the prospects, achievements, challenges and opportunities for implementing intermittent preventive treatment for malaria in pregnancy (IPTp) in Tanzania in light of national antenatal care (ANC) guidelines and ability of service providers to comply with them....

  5. E-Commerce Content in Business School Curriculum: Opportunities and Challenges.

    Science.gov (United States)

    Krovi, Ravindra; Vijayaraman, B. S.

    2000-01-01

    Explores the opportunities and challenges of introducing e-commerce concepts in business school curriculums. Examines the knowledge components of electronic commerce, including Web-based technology skills; and discusses the need for faculty training and development. (Author/LRW)

  6. Building waste management in Bulgaria: challenges and opportunities

    International Nuclear Information System (INIS)

    Hadjieva-Zaharieva, R.; Dimitrova, E.; Buyle-Bodin, Francois

    2003-01-01

    Building waste recycling as aggregates is a modern approach for preventing environmental pollution through both reducing the stocks of waste and decreasing the use of natural aggregates. The reuse of building waste is a relatively new issue for Bulgaria despite the existing considerable quantity of building waste and the significant changes in the environmental rules applied. The paper discusses generated and potential waste streams in Bulgaria in the context of the social and economic restructuring and recent urban development undergone by the country. The main preliminary conditions for developing the recycling activity such as: streams of building waste, experience in recycling, technical and environmental standardization, appropriate technologies, etc. are examined. The authors analyze current practice and research activities with regard to the implementation of advanced EU building-waste recycling methods. Conclusions are drawn about existing opportunities and the priorities of the needed building waste management strategy in the country

  7. Energy and environment in the ASEAN: challenges and opportunities

    International Nuclear Information System (INIS)

    Karki, S.K.; Mann, M.D.; Salehfar, Hossein

    2005-01-01

    The Association of Southeast Asian Nations (ASEAN) is one of the most dynamic economic regions of the world. Its economy is linked with its diverse energy resources, high-level urbanization, and rapid industrialization. ASEAN's growing economy in the last two decades has increased the concern of sustainable development in the face of deteriorating energy security, environmental pollution, and economic hardship in energy investment. However, opportunities exist to tackle these issues. Increasing energy efficiency (both supply and demand side), exploitation of renewable energy resources (mostly hydro), and an integrated approach on energy resource management are some of the important approaches toward the sustainable energy path. Because the options are capital-intensive, cooperation and development of appropriate institutional structures and decision mechanism across the region are urgently needed

  8. Biofuel chain development in Germany: Organisation, opportunities, and challenges

    International Nuclear Information System (INIS)

    Dautzenberg, Kirsti; Hanf, Jon

    2008-01-01

    Increasing production activities have been observed in many EU member states since the EU Commission sent a clear signal establishing and supporting the bioenergy industry. This article discusses current sector developments and therewith evolving biofuel value chain activities and management requirements by means of two German biofuel processing firms. Usually, the processing company can be regarded as the initiator of the regional value chains. In order to safeguard the high initial investments and secure efficient supply, the processing company relies on contract farming or profit participation rights rather than spot market interactions. In addition to discussing that point, this paper also explores opportunities and threats for the suppliers of raw materials as well as for the processors. (author)

  9. Microscale technology and biocatalytic processes: opportunities and challenges for synthesis.

    Science.gov (United States)

    Wohlgemuth, Roland; Plazl, Igor; Žnidaršič-Plazl, Polona; Gernaey, Krist V; Woodley, John M

    2015-05-01

    Despite the expanding presence of microscale technology in chemical synthesis and energy production as well as in biomedical devices and analytical and diagnostic tools, its potential in biocatalytic processes for pharmaceutical and fine chemicals, as well as related industries, has not yet been fully exploited. The aim of this review is to shed light on the strategic advantages of this promising technology for the development and realization of biocatalytic processes and subsequent product recovery steps, demonstrated with examples from the literature. Constraints, opportunities, and the future outlook for the implementation of these key green engineering methods and the role of supporting tools such as mathematical models to establish sustainable production processes are discussed. Copyright © 2015 Elsevier Ltd. All rights reserved.

  10. Biogeochemistry: Some Opportunities and Challenges for the Future

    International Nuclear Information System (INIS)

    Likens, Gene E.

    2004-01-01

    There are major opportunities for big, important questions to drive biogeochemical research in the future. Some suggestions are presented, such as: what are the controls on N loss and retention in watershed-ecosystems; what are the rates and controls on biological N fixation and denitrification in diverse ecosystems; how does scale (temporal and spatial) control biogeochemical flux and cycling; what controls the apparent and actual weathering rates in terrestrial ecosystems and what is the fate of the weathered products; how can biogeochemical function best be integrated on regional to global scales; and what are the quantitative interrelationships between hydrologic cycles and biogeochemical cycles? Some brief examples and approaches to address such questions, for example, the value of multidisciplinary teams for addressing complicated questions,and the use of sophisticated tools (e.g., stable isotopes, spatial statistics, remote sensing), are presented

  11. Japanese Martial Arts as Popular Culture: Teaching Opportunity and Challenge

    Directory of Open Access Journals (Sweden)

    Stephen Robert NAGY

    2015-07-01

    Full Text Available Japanese martial arts, here after Japanese budō, are popular cultural icons that are found in films, comics, video games and books. Teaching Japanese budō at university offers a novel way to teach about East Asian and in particular Japanese culture, history, and philosophy while including ideas about the globalization and the localization of culture. Question though remains as to how and what should we teach about the popular culture of Japanese budō at the university level? This paper found that a comprehensive approach to teaching about budō was effective. By using many kinds of materials and the incorporation of opportunities to experience budō and to try budō, students were better able to grasp the historical, cultural and religious characteristics of budō.

  12. Artificial Intelligence (AI) in Healthcare Market: Market Trend with Boom Opportunities in Upcoming Years

    OpenAIRE

    Rahul Gautam

    2018-01-01

    The global artificial intelligence in healthcare market is expected to observe an extensive growth in the coming years, led by growing need for precision medicine, increasing application of big data in healthcare industry, and rising need for coordination between healthcare workforce and patients. The products in the global market are categorized as hardware, software and services, with software being the largest contributor in 2016 and the category is also projected to witness significant gr...

  13. Improving Quality of Care in Primary Health-Care Facilities in Rural Nigeria: Successes and Challenges.

    Science.gov (United States)

    Ugo, Okoli; Ezinne, Eze-Ajoku; Modupe, Oludipe; Nicole, Spieker; Winifred, Ekezie; Kelechi, Ohiri

    2016-01-01

    Nigeria has a high population density but a weak health-care system. To improve the quality of care, 3 organizations carried out a quality improvement pilot intervention at the primary health-care level in selected rural areas. To assess the change in quality of care in primary health-care facilities in rural Nigeria following the provision of technical governance support and to document the successes and challenges encountered. A total of 6 states were selected across the 6 geopolitical zones of the country. However, assessments were carried out in 40 facilities in only 5 states. Selection was based on location, coverage, and minimum services offered. The facilities were divided randomly into 2 groups. The treatment group received quality-of-care assessment, continuous feedback, and improvement support, whereas the control group received quality assessment and no other support. Data were collected using the SafeCare Healthcare Standards and managed on the SafeCare Data Management System-AfriDB. Eight core areas were assessed at baseline and end line, and compliance to quality health-care standards was compared. Outcomes from 40 facilities were accepted and analyzed. Overall scores increased in the treatment facilities compared to the control facilities, with strong evidence of improvement ( t = 5.28, P = .0004) and 11% average improvement, but no clear pattern of improvement emerged in the control group. The study demonstrated governance support and active community involvement offered potential for quality improvement in primary health-care facilities.

  14. Advancing HIV research with pregnant women: navigating challenges and opportunities.

    Science.gov (United States)

    Krubiner, Carleigh B; Faden, Ruth R; Cadigan, R Jean; Gilbert, Sappho Z; Henry, Leslie M; Little, Margaret O; Mastroianni, Anna C; Namey, Emily E; Sullivan, Kristen A; Lyerly, Anne D

    2016-09-24

    Concerns about including pregnant women in research have led to a dearth of evidence to guide safe and effective treatment and prevention of HIV in pregnancy. To better understand why these evidence gaps persist and inform guidance for responsible inclusion of pregnant women in the HIV research agenda, we aimed to learn what HIV experts perceive as barriers and constraints to conducting this research. We conducted a series of group and one-on-one consultations with 62 HIV investigators and clinicians to elicit their views and experiences conducting HIV research involving pregnant women. Thematic analysis was used to identify priorities and perceived barriers to HIV research with pregnant women. Experts discussed a breadth of needed research, including safety, efficacy, and appropriate dosing of: newer antiretrovirals for pregnant women, emerging preventive strategies, and treatment for coinfections. Challenges to conducting research on pregnancy and HIV included ethical concerns, such as how to weigh risks and benefits in pregnancy; legal concerns, such as restrictive interpretations of current regulations and liability issues; financial and professional disincentives, including misaligned funder priorities and fear of reputational damage; and analytical and logistical complexities, such as challenges recruiting and retaining pregnant women to sufficiently power analyses. Investigators face numerous challenges to conducting needed HIV research with pregnant women. Advancing such research will require clearer guidance regarding ethical and legal uncertainties; incentives that encourage rather than discourage investigators to undertake such research; and a commitment to earlier development of safety and efficacy data through creative trial designs.

  15. Renewable energy scenario in India: Opportunities and challenges

    Science.gov (United States)

    Sen, Souvik; Ganguly, Sourav; Das, Ayanangshu; Sen, Joyjeet; Dey, Sourav

    2016-10-01

    Majority of the power generation in India is carried out by conventional energy sources, coal and fossil fuels being the primary ones, which contribute heavily to greenhouse gas emission and global warming. The Indian power sector is witnessing a revolution as excitement grips the nation about harnessing electricity from various renewable energy sources. Electricity generation from renewable sources is increasingly recognized to play an important role for the achievement of a variety of primary and secondary energy policy goals, such as improved diversity and security of energy supply, reduction of local pollutant and global greenhouse gas emissions, regional and rural development, and exploitation of opportunities for fostering social cohesion, value addition and employment generation at the local and regional level. This focuses the solution of the energy crisis on judicious utilization of abundant the renewable energy resources, such as biomass, solar, wind, geothermal and ocean tidal energy. This paper reviews the renewable energy scenario of India as well as extrapolates the future developments keeping in view the consumption, production and supply of power. Research, development, production and demonstration have been carried out enthusiastically in India to find a feasible solution to the perennial problem of power shortage for the past three decades. India has obtained application of a variety of renewable energy technologies for use in different sectors too. There are ample opportunities with favorable geology and geography with huge customer base and widening gap between demand and supply. Technological advancement, suitable regulatory policies, tax rebates, efficiency improvement in consequence to R&D efforts are the few pathways to energy and environment conservation and it will ensure that these large, clean resource bases are exploited as quickly and cost effectively as possible. This paper gives an overview of the potential renewable energy resources

  16. Challenges and Opportunities To Deliver Research Services to Parliamentarians in the Japanese Diet.

    Science.gov (United States)

    Takeda, Michiyo

    This paper outlines the challenges and opportunities for the services of the Japanese National Diet Library (NDL), especially the Research and Legislative Reference Bureau by using a SWOT (Strength, Weaknesses, Opportunities, and Threats) analysis. The introduction lists the major goals of the NDL's reform. The second section discusses the NDL's…

  17. Human Subjects Protection and Technology in Prevention Science: Selected Opportunities and Challenges

    OpenAIRE

    Pisani, Anthony R.; Wyman, Peter A.; Mohr, David C.; Perrino, Tatiana; Gallo, Carlos; Villamar, Juan; Kendziora, Kimberly; Howe, George W.; Sloboda, Zili; Brown, C. Hendricks

    2016-01-01

    Internet-connected devices are changing the way people live, work, and relate to one another. For prevention scientists, technological advances create opportunities to promote the welfare of human subjects and society. The challenge is to obtain the benefits while minimizing risks. In this article, we use the guiding principles for ethical human subjects research and proposed changes to the Common Rule regulations, as a basis for discussing selected opportunities and challenges that new techn...

  18. The challenges of healthcare delivery to people with multiple sclerosis in Iran.

    Science.gov (United States)

    Yazdannik, Ahmadreza; Abolhassani, Shahla; Taleghani, Fariba; Zamani, Ahmadreza

    2015-01-01

    Multiple sclerosis (MS) is a chronic disease prevalent in young and middle-aged people. Patients with MS often have numerous complicated needs and, consequently, require a broad range of health services. Results of a number of studies indicate that patients' needs are only partially met. This study was conducted to explore the challenges of healthcare delivery to patients with MS in Iran. In this qualitative case study, 43 participants selected through purposeful sampling were interviewed using semi-structured method in the cities of Isfahan and Tehran in 2012-2013. Besides the interview, documentations relevant to healthcare delivery were collected from different sources, including websites of all Iranian universities of medical sciences, insurance organizations, patients' weblogs, news agencies, the MS Center forum for MS patients, and MS Payam bimonthly. The data were analyzed through the constant comparative analysis. The data were categorized into four main categories, including functional challenges (diagnosis problems, failure to pay attention to patient needs, failure to follow-up, and miscommunication), administrative challenges (resource allocation and supervision), policy-making challenges (lack of comprehensive services, bureaucracy, and problems in provision of medications), and structural challenges (difficult access to services, lack of comprehensive centers, space limit, and long wait). Despite all attempts of governmental and nongovernmental organizations for healthcare delivery to MS patients, these services cannot satisfy all needs of the patients. In this regard, service providers and administrators should pay more attention to the needs and expectations of patients and their families.

  19. Continuous Glucose Monitoring: A Review of Successes, Challenges, and Opportunities.

    Science.gov (United States)

    Rodbard, David

    2016-02-01

    Continuous glucose monitoring (CGM) provides information unattainable by intermittent capillary blood glucose, including instantaneous real-time display of glucose level and rate of change of glucose, alerts and alarms for actual or impending hypo- and hyperglycemia, "24/7" coverage, and the ability to characterize glycemic variability. Progressively more accurate and precise, reasonably unobtrusive, small, comfortable, user-friendly devices connect to the Internet to share information and are sine qua non for a closed-loop artificial pancreas. CGM can inform, educate, motivate, and alert people with diabetes. CGM is medically indicated for patients with frequent, severe, or nocturnal hypoglycemia, especially in the presence of hypoglycemia unawareness. Surprisingly, despite tremendous advances, utilization of CGM has remained fairly limited to date. Barriers to use have included the following: (1) lack of Food and Drug Administration approval, to date, for insulin dosing ("nonadjuvant use") in the United States and for use in hospital and intensive care unit settings; (2) cost and variable reimbursement; (3) need for recalibrations; (4) periodic replacement of sensors; (5) day-to-day variability in glycemic patterns, which can limit the predictability of findings based on retrospective, masked "professional" use; (6) time, implicit costs, and inconvenience for uploading of data for retrospective analysis; (7) lack of fair and reasonable reimbursement for physician time; (8) inexperience and lack of training of physicians and other healthcare professionals regarding interpretation of CGM results; (9) lack of standardization of software methods for analysis of CGM data; and (10) need for professional medical organizations to develop and disseminate additional clinical practice guidelines regarding the role of CGM. Ongoing advances in technology and clinical research have addressed several of these barriers. Use of CGM in conjunction with an insulin pump with

  20. Gas-fired Power Generation in India: Challenges and opportunities

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    India's fast growing economy needs to add 100,000 MW power generating capacity between 2002-2012. Given limitations to the use of coal in terms of environmental considerations, quality and supply constraints, gas is expected to play an increasingly important role in India's power sector. This report briefs NMC Delegates on the potential for gas-fired power generation in India and describes the challenges India faces to translate the potential for gas-fired power generation into reality.

  1. International ESCO business opportunities and challenges: a Japanese case study

    Energy Technology Data Exchange (ETDEWEB)

    Vine, E.L. [Lawrence Berkeley National Lab., CA (United States); Murakoshi, Chiharu; Nakagami, Hidetoshi [Jyukankyo Research Inst., Tokyo (Japan)

    1998-06-01

    U.S. energy service companies (ESCOs) are very interested in expanding their businesses outside the U.S. Despite the needs of many countries for ESCO involvement, ESCOs face many challenges (i.e. marketing, financial, institutional, political and cultural impediments). Using Japan as an example, we present (i) impediments to the development of an ESCO industry, (ii) general guidance for helping Japan to develop its own ESCO industry, (iii) specific ESCO development strategies for Japan, and (iv) recommendations to U.S. companies considering joint ventures between U.S. ESCOs and Japanese companies. (Author)

  2. Opportunities and challenges in social pharmacy and pharmacy practice research

    DEFF Research Database (Denmark)

    Almarsdóttir, Anna Birna; Kaae, Susanne; Traulsen, Janine M

    2014-01-01

    Pharmacy practice and social pharmacy are two important research areas within pharmaceutical and health sciences. As the disciplines have undergone and are still undergoing changes, it is useful to reflect on the current state of their research as the basis for discussing further development....... The two areas are currently beset by a lack of consensus and charged all too often with evaluating narrowly focused pharmacy services. With the added challenge of diminished funding for research and the pressures to publish results, these fields have to accommodate a much broader research framework than...

  3. Genesis, challenges and opportunities for colloidal lead halide perovskite nanocrystals

    Science.gov (United States)

    Akkerman, Quinten A.; Rainò, Gabriele; Kovalenko, Maksym V.; Manna, Liberato

    2018-05-01

    Lead halide perovskites (LHPs) in the form of nanometre-sized colloidal crystals, or nanocrystals (NCs), have attracted the attention of diverse materials scientists due to their unique optical versatility, high photoluminescence quantum yields and facile synthesis. LHP NCs have a `soft' and predominantly ionic lattice, and their optical and electronic properties are highly tolerant to structural defects and surface states. Therefore, they cannot be approached with the same experimental mindset and theoretical framework as conventional semiconductor NCs. In this Review, we discuss LHP NCs historical and current research pursuits, challenges in applications, and the related present and future mitigation strategies explored.

  4. International ESCO business opportunities and challenges: a Japanese case study

    International Nuclear Information System (INIS)

    Vine, E.L.; Murakoshi, Chiharu; Nakagami, Hidetoshi

    1998-01-01

    U.S. energy service companies (ESCOs) are very interested in expanding their businesses outside the U.S. Despite the needs of many countries for ESCO involvement, ESCOs face many challenges (i.e. marketing, financial, institutional, political and cultural impediments). Using Japan as an example, we present (i) impediments to the development of an ESCO industry, (ii) general guidance for helping Japan to develop its own ESCO industry, (iii) specific ESCO development strategies for Japan, and (iv) recommendations to U.S. companies considering joint ventures between U.S. ESCOs and Japanese companies. (Author)

  5. Challenges and opportunities in integration of design and control

    DEFF Research Database (Denmark)

    Huusom, Jakob Kjøbsted

    2015-01-01

    Process synthesis and design of plant operation are related topics but current industrial practice solves these problems sequentially. The implication of this sequential strategy may result in design of processing systems which are very hard to control. This paper presents a discussion on drivers...... for an integrated approach and outlines the challenges in formulation of such a multi-objective synthesis problem. This discussion is viewed in relation to some of the changing trends in the industry. Significant results have been published which in different ways seek to handle the integrated problem. Further...

  6. 'Big data' in pharmaceutical science: challenges and opportunities.

    Science.gov (United States)

    Dossetter, Al G; Ecker, Gerhard; Laverty, Hugh; Overington, John

    2014-05-01

    Future Medicinal Chemistry invited a selection of experts to express their views on the current impact of big data in drug discovery and design, as well as speculate on future developments in the field. The topics discussed include the challenges of implementing big data technologies, maintaining the quality and privacy of data sets, and how the industry will need to adapt to welcome the big data era. Their enlightening responses provide a snapshot of the many and varied contributions being made by big data to the advancement of pharmaceutical science.

  7. Western United States Dams Challenges Faced, Options, and Opportunities

    Science.gov (United States)

    Raff, D.

    2017-12-01

    Water management in the Western United States relies significantly upon a fleet of small to very large engineered dams to store water during times of runoff and distribute that water during times of need. Much of this infrastructure is Federally owned and/or operated, and was designed and funded during the first half of the twentieth century through a complex set of repayment contracts for Federally authorized purposes addressing water supply, recreation, and hydropower, and other water management objectives. With environmental laws, namely the Endangered Species Act, and other environmental concerns taking a more active role in water resources in the mid to latter half of the twentieth century, this infrastructure is being stressed even greater than anticipated to provide authorized purposes. Additionally, weather and climate norms being experienced are certainly near the edges, if not outside, of anticipated variability in the climate and hydrology scenarios for which the infrastructure was designed. And, finally, these dams, economically designed for a lifespan of 50 - 100 years, are experiencing maintenance challenges from routine to significant. This presentation will focus on identifying some of the history and challenges facing the water infrastructure in the Western United States. Additionally, some perspectives on future paths to meet the needs of western irrigation and hydropower production will be provided.

  8. The global conduct of cancer clinical trials: challenges and opportunities.

    Science.gov (United States)

    Barrios, Carlos H; Werutsky, Gustavo; Martinez-Mesa, Jeovany

    2015-01-01

    The nature of clinical research has changed substantially over the last 2 decades, evolving from being centered almost exclusively in developed countries to a more global scenario that is increasingly involving less developed regions of the world. Pharmaceutical companies and some academic cooperative groups have been conducting challenging, large pivotal registration studies with multinational participation. The much more needed globalization of academic research demands particular attention and represents a worthwhile subject for a more profound discussion. The requirement of large sample sizes and the potential for fast recruitment leading to a speedy completion of clinical studies are probably the most important factors that have fueled globalization of studies. Reduced operational costs and the ability to expedite the regulatory approval of drugs in various countries or regions are also important drivers. Globalization of research should be seen as having a much wider effect in the societies involved, in particular, when we consider public health, economic, social, and ethical implications. Most importantly, the process of expanding the network of clinical research sites also fosters the integration and the development of closer relationships among investigators at a global level. We consider this an essential element that should remain a prominent element in the discussion. In this article, we address the underlying reasons for globalization and we highlight some of the scientific and ethical concerns arising as a consequence. Finally, some strategies to address and mitigate the challenges of conducting multinational clinical research are proposed.

  9. Genetically modified T cells in cancer therapy: opportunities and challenges

    Directory of Open Access Journals (Sweden)

    Michaela Sharpe

    2015-04-01

    Full Text Available Tumours use many strategies to evade the host immune response, including downregulation or weak immunogenicity of target antigens and creation of an immune-suppressive tumour environment. T cells play a key role in cell-mediated immunity and, recently, strategies to genetically modify T cells either through altering the specificity of the T cell receptor (TCR or through introducing antibody-like recognition in chimeric antigen receptors (CARs have made substantial advances. The potential of these approaches has been demonstrated in particular by the successful use of genetically modified T cells to treat B cell haematological malignancies in clinical trials. This clinical success is reflected in the growing number of strategic partnerships in this area that have attracted a high level of investment and involve large pharmaceutical organisations. Although our understanding of the factors that influence the safety and efficacy of these therapies has increased, challenges for bringing genetically modified T-cell immunotherapy to many patients with different tumour types remain. These challenges range from the selection of antigen targets and dealing with regulatory and safety issues to successfully navigating the routes to commercial development. However, the encouraging clinical data, the progress in the scientific understanding of tumour immunology and the improvements in the manufacture of cell products are all advancing the clinical translation of these important cellular immunotherapies.

  10. E-book usage: counting the challenges and opportunities

    Directory of Open Access Journals (Sweden)

    Angela Conyers

    2017-07-01

    Full Text Available Academic libraries are spending a growing proportion of their increasingly stretched budgets on e-books each year. Within this context, demonstrating a return on investment is imperative, but gathering data about e-resource usage is not always easy.    This article summarizes how libraries and library consortia are acquiring and evaluating e-books, how usage statistics feature within library workflows, the issues faced in doing so and the resulting impact of these issues on understanding usage and informing purchasing of new titles. Discussions with publishers indicate how usage data are being used within the organization, the requirements of customers and the challenges involved in providing usage data for e-books. Assessing and evaluating e-book usage is a complex and challenging task with processes and workflows in development. A transition from print to e-books represents a significant change for libraries, and the availability of reliable usage statistics to support purchase decisions is vital. The article is based on a series of case study interviews with representatives from a small cross-section of academic libraries, library consortia, publishers and aggregators.    This work is of interest to anyone with responsibility for creating, managing, developing, delivering and supporting usage statistics and standards for e-books.

  11. Change, Challenge and Opportunity: Departments of Medicine and Their Leaders.

    Science.gov (United States)

    Feussner, John R; Landefeld, C Seth; Weinberger, Steven E

    2016-01-01

    Academic Health Centers are evolving to larger and more complex Academic Health Systems (AHS), reflecting financial stresses requiring them to become nimble, efficient, and patient (consumer) and faculty (employee) focused. The evolving AHS organization includes many positive attributes: unity of purpose, structural integration, collaboration and teamwork, alignment of goals with resource allocation, and increased financial success. The organization, leadership, and business acumen of the AHS influence directly opportunities for Departments of Medicine. Just as leadership capabilities of the AHS affect its future success, the same is true for departmental leadership. The Department of Medicine is no longer a quasi- autonomous entity, and the chairperson is no longer an independent decision-maker. Departments of Medicine will be most successful if they maintain internal unity and cohesion by not fragmenting along specialty lines. Departments with larger endowments or those with public financial support have more flexibility when investing in the academic missions. The chairpersons of the future should serve as change agents while simultaneously adopting a "servant leadership" model. Chairpersons with executive and team building skills, and business acumen and experience, are more likely to succeed in managing productive and lean departments. Quality of patient care and service delivery enhance the department's effectiveness and credibility and assure access to additional financial resources to subsidize the academic missions. Moreover, the drive for excellence, high performance and growth will fuel financial solvency. Copyright © 2016 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved.

  12. Challenges and opportunities for tissue-engineering polarized epithelium.

    Science.gov (United States)

    Paz, Ana C; Soleas, John; Poon, James C H; Trieu, Dennis; Waddell, Thomas K; McGuigan, Alison P

    2014-02-01

    The epithelium is one of the most important tissue types in the body and the specific organization of the epithelial cells in these tissues is important for achieving appropriate function. Since many tissues contain an epithelial component, engineering functional epithelium and understanding the factors that control epithelial maturation and organization are important for generating whole artificial organ replacements. Furthermore, disruption of the cellular organization leads to tissue malfunction and disease; therefore, engineered epithelium could provide a valuable in vitro model to study disease phenotypes. Despite the importance of epithelial tissues, a surprisingly limited amount of effort has been focused on organizing epithelial cells into artificial polarized epithelium with an appropriate structure that resembles that seen in vivo. In this review, we provide an overview of epithelial tissue organization and highlight the importance of cell polarization to achieve appropriate epithelium function. We next describe the in vitro models that exist to create polarized epithelium and summarize attempts to engineer artificial epithelium for clinical use. Finally, we highlight the opportunities that exist to translate strategies from tissue engineering other tissues to generate polarized epithelium with a functional structure.

  13. Opportunities and Challenges for Nutritional Proteomics in Cancer Prevention12

    Science.gov (United States)

    Romagnolo, Donato F.; Milner, John A.

    2012-01-01

    Knowledge gaps persist about the efficacy of cancer prevention strategies based on dietary food components. Adaptations to nutrient supply are executed through tuning of multiple protein networks that include transcription factors, histones, modifying enzymes, translation factors, membrane and nuclear receptors, and secreted proteins. However, the simultaneous quantitative and qualitative measurement of all proteins that regulate cancer processes is not practical using traditional protein methodologies. Proteomics offers an attractive opportunity to fill this knowledge gap and unravel the effects of dietary components on protein networks that impinge on cancer. The articles presented in this supplement are from talks proffered in the “Nutrition Proteomics and Cancer Prevention” session at the American Institute for Cancer Research Annual Research Conference on Food, Nutrition, Physical Activity and Cancer held in Washington, DC on October 21 and 22, 2010. Recent advances in MS technologies suggest that studies in nutrition and cancer prevention may benefit from the adoption of proteomic tools to elucidate the impact on biological processes that govern the transition from normal to malignant phenotype; to identify protein changes that determine both positive and negative responses to food components; to assess how protein networks mediate dose-, time-, and tissue-dependent responses to food components; and, finally, for predicting responders and nonresponders. However, both the limited accessibility to proteomic technologies and research funding appear to be hampering the routine adoption of proteomic tools in nutrition and cancer prevention research. PMID:22649262

  14. Modelling nutritional mutualisms: challenges and opportunities for data integration.

    Science.gov (United States)

    Clark, Teresa J; Friel, Colleen A; Grman, Emily; Shachar-Hill, Yair; Friesen, Maren L

    2017-09-01

    Nutritional mutualisms are ancient, widespread, and profoundly influential in biological communities and ecosystems. Although much is known about these interactions, comprehensive answers to fundamental questions, such as how resource availability and structured interactions influence mutualism persistence, are still lacking. Mathematical modelling of nutritional mutualisms has great potential to facilitate the search for comprehensive answers to these and other fundamental questions by connecting the physiological and genomic underpinnings of mutualisms with ecological and evolutionary processes. In particular, when integrated with empirical data, models enable understanding of underlying mechanisms and generalisation of principles beyond the particulars of a given system. Here, we demonstrate how mathematical models can be integrated with data to address questions of mutualism persistence at four biological scales: cell, individual, population, and community. We highlight select studies where data has been or could be integrated with models to either inform model structure or test model predictions. We also point out opportunities to increase model rigour through tighter integration with data, and describe areas in which data is urgently needed. We focus on plant-microbe systems, for which a wealth of empirical data is available, but the principles and approaches can be generally applied to any nutritional mutualism. © 2017 John Wiley & Sons Ltd/CNRS.

  15. Customization of Curriculum Materials in Science: Motives, Challenges, and Opportunities

    Science.gov (United States)

    Romine, William L.; Banerjee, Tanvi

    2012-02-01

    Exemplary science instructors use inquiry to tailor content to student's learning needs; traditional textbooks treat science as a set of facts and a rigid curriculum. Publishers now allow instructors to compile pieces of published and/or self-authored text to make custom textbooks. This brings numerous advantages, including the ability to produce smaller, cheaper text and added flexibility on the teaching models used. Moreover, the internet allows instructors to decentralize textbooks through easy access to educational objects such as audiovisual simulations, individual textbook chapters, and scholarly research articles. However, these new opportunities bring with them new problems. With educational materials easy to access, manipulate and duplicate, it is necessary to define intellectual property boundaries, and the need to secure documents against unlawful copying and use is paramount. Engineers are developing and enhancing information embedding technologies, including steganography, cryptography, watermarking, and fingerprinting, to label and protect intellectual property. While these are showing their utility in securing information, hackers continue to find loop holes in these protection schemes, forcing engineers to constantly assess the algorithms to make them as secure as possible. As newer technologies rise, people still question whether custom publishing is desirable. Many instructors see the process as complex, costly, and substandard in comparison to using traditional text. Publishing companies are working to improve attitudes through advertising. What lacks is peer reviewed evidence showing that custom publishing improves learning. Studies exploring the effect of custom course materials on student attitude and learning outcomes are a necessary next step.

  16. Superefficient Refrigerators: Opportunities and Challenges for Efficiency Improvement Globally

    Energy Technology Data Exchange (ETDEWEB)

    Shah, Nihar; Park, Won Young; Bojda, Nicholas; McNeil, Michael A.

    2014-08-01

    As an energy-intensive mainstream product, residential refrigerators present a significant opportunity to reduce electricity consumption through energy efficiency improvements. Refrigerators expend a considerable amount of electricity during normal use, typically consuming between 100 to 1,000 kWh of electricity per annum. This paper presents the results of a technical analysis done for refrigerators in support of the Super-efficient Equipment and Appliance Deployment (SEAD) initiative. Beginning from a base case representative of the average unit sold in India, we analyze efficiency improvement options and their corresponding costs to build a cost-versus-efficiency relationship. We then consider design improvement options that are known to be the most cost effective and that can improve efficiency given current design configurations. We also analyze and present additional super-efficient options, such as vacuum-insulated panels. We estimate the cost of conserved electricity for the various options, allowing flexible program design for market transformation programs toward higher efficiency. We estimate ~;;160TWh/year of energy savings are cost effective in 2030, indicating significant potential for efficiency improvement in refrigerators in SEAD economies and China.

  17. [Methods, challenges and opportunities for big data analyses of microbiome].

    Science.gov (United States)

    Sheng, Hua-Fang; Zhou, Hong-Wei

    2015-07-01

    Microbiome is a novel research field related with a variety of chronic inflamatory diseases. Technically, there are two major approaches to analysis of microbiome: metataxonome by sequencing the 16S rRNA variable tags, and metagenome by shot-gun sequencing of the total microbial (mainly bacterial) genome mixture. The 16S rRNA sequencing analyses pipeline includes sequence quality control, diversity analyses, taxonomy and statistics; metagenome analyses further includes gene annotation and functional analyses. With the development of the sequencing techniques, the cost of sequencing will decrease, and big data analyses will become the central task. Data standardization, accumulation, modeling and disease prediction are crucial for future exploit of these data. Meanwhile, the information property in these data, and the functional verification with culture-dependent and culture-independent experiments remain the focus in future research. Studies of human microbiome will bring a better understanding of the relations between the human body and the microbiome, especially in the context of disease diagnosis and therapy, which promise rich research opportunities.

  18. DCFTA Implementation: Opportunities and Challenges for Ukrainian Entrepreneurs

    Directory of Open Access Journals (Sweden)

    Oleksandr KUBATKO

    2016-12-01

    Full Text Available The paper deals with the analysis of Ukrainian entrepreneurs readiness for implementation of Deep and Comprehensive Free Trade Area (DCFTA. The authors analyzed the ongoing condition for running business in Ukraine, and results were in favor negative industrial business tendencies combined with macroeconomic instability. Moreover, the military confrontation in the East of Ukraine has had negative consequences for the social, moral and economic situation in the country. Authors have estimated the chances and goals of Ukrainian entrepreneurs to be achieved using the DCFTA. Thus, the effect of DCFTA implementation could provide 6 % of the additional GDP in the medium term. The share of export to EU in total Ukrainian export of goods and services has increased from 26.7 % in 2013 to 32.8 % in 2015. The entrepreneurs of agriculture sector and textile industry are expected to receive the most positive effect of DCFTA implementation. Thus, the export of the cereal crops has increased by 3 % in 2015 compare with 2013. In addition, the export of Electrical machinery and equipment also has increased by 3% in 2015 comparing to 2013. Moreover, DCFTA implementation allowed opening new boundaries and opportunities for entrepreneurs in IT sector. At the same time, the machine building industry is expected to be very sensitive to the DCFTA implementation due the low competitiveness.

  19. Postmodernism and the Church: An Opportunity and a Challenge

    Directory of Open Access Journals (Sweden)

    Timothy Hynes

    2016-09-01

    Full Text Available Postmodernism is, in many respects, a term that has lost most of its cultural and academic cachet. This does not, however, mean that the themes, context, and conditions to which it referred are no longer relevant. In this essay, I will briefly review the latest reports which show a decreasing interest in organized religion, and interpret these results as symptomatic of a larger change in the state of knowledge. To this end, I will examine Jean ‑François Lyotard’s analysis of the loss of metanarratives as a way of understanding the implicit rules of the dialogue that occurs between the theist and the atheist or agnostic. Next, I will note the unique capacity of beauty to transcend the diverse language games played by both sides of the conversation. I will conclude by contending that this characteristic of beauty offers a kind of common ground which can be built upon, fostering further dialogue as well as an opportunity for evangelization.

  20. Challenges And Opportunities For Coal Gasification In Developing Countries

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-10-01

    Coal gasification for chemicals, gaseous and liquid fuels production can fulfil an important strategic need in those developing countries where coal is the primary fuel source and oil and gas energy security is an issue. At the same time, the establishment of major projects in such countries can be problematical for a number of technical and economic reasons, although it is encouraging that some projects appear to be moving forward. There are two developing countries where coal conversion projects to produce chemicals, gaseous and liquid fuels have been taken forward strongly. The first is South Africa, which established the world's only commercial-scale coal-to-liquids and coal-to-chemicals facilities at Secunda and Sasolburg respectively. The other is China, where there is a major gasification-based coal conversion development and deployment programme that is set to become a significant, large-scale commercial element in the nation's energy development plans. This will provide further major opportunities for the deployment of large-scale coal gasification technologies, various syngas conversion units and catalysts for the subsequent production of the required products. The role of China is likely to be critical in the dissemination of such technologies to other developing countries as it can not only provide the technical expertise but also financially underpin such projects, including the associated infrastructure needs.

  1. A new generation of healthcare buildings in South Africa: complexities and opportunities for greening

    CSIR Research Space (South Africa)

    De Jager, Peta

    2012-07-01

    Full Text Available , efficient, healing environment desirable for healthcare delivery. In South Africa there has been a commitment to transform the healthcare sector through the introduction of the national health insurance system which is to be unfolded over a 14 year period...

  2. Opportunities and challenges for multicriteria assessment of food system sustainability

    Directory of Open Access Journals (Sweden)

    Hugo F. Alrøe

    2016-03-01

    Full Text Available The focus of the Special Feature on "Multicriteria assessment of food system sustainability" is on the complex challenges of making and communicating overall assessments of food systems sustainability based on multiple and varied criteria. Four papers concern the choice and development of appropriate tools for making multicriteria sustainability assessments that handle built-in methodological conflicts and trade-offs between different assessment objectives. They underscore the value of linking diverse methods and tools, or nesting and stepping their deployment, to help build resilience and sustainability. They conclude that there is no one tool, one framework, or one indicator set that is appropriate for the different purposes and contexts of sustainability assessment. The process of creating the assessment framework also emerges as important: if the key stakeholders are not given a responsible and full role in the development of any assessment tool, it is less likely to be fit for their purpose and they are unlikely to take ownership or have confidence in it. Six other papers reflect on more fundamental considerations of how assessments are based in different scientific perspectives and on the role of values, motivation, and trust in relation to assessments in the development of more sustainable food systems. They recommend a radical break with the tradition of conducting multicriteria assessment from one hegemonic perspective to considering multiple perspectives. Collectively the contributions to this Special Feature identify three main challenges for improved multicriteria assessment of food system sustainability: (i how to balance different types of knowledge to avoid that the most well-known, precise, or easiest to measure dimensions of sustainability gets the most weight; (ii how to expose the values in assessment tools and choices to allow evaluation of how they relate to the ethical principles of sustainable food systems, to societal

  3. Data science and symbolic AI: Synergies, challenges and opportunities

    KAUST Repository

    Hoehndorf, Robert

    2017-06-02

    Symbolic approaches to artificial intelligence represent things within a domain of knowledge through physical symbols, combine symbols into symbol expressions, and manipulate symbols and symbol expressions through inference processes. While a large part of Data Science relies on statistics and applies statistical approaches to artificial intelligence, there is an increasing potential for successfully applying symbolic approaches as well. Symbolic representations and symbolic inference are close to human cognitive representations and therefore comprehensible and interpretable; they are widely used to represent data and metadata, and their specific semantic content must be taken into account for analysis of such information; and human communication largely relies on symbols, making symbolic representations a crucial part in the analysis of natural language. Here we discuss the role symbolic representations and inference can play in Data Science, highlight the research challenges from the perspective of the data scientist, and argue that symbolic methods should become a crucial component of the data scientists’ toolbox.

  4. Physics Education Research efforts to promote diversity: Challenges and opportunities

    Science.gov (United States)

    Brahmia, Suzanne

    2015-04-01

    We begin this talk with a brief description of the gender and ethnic diversity of the physics community. We then discuss several current efforts within Physics Education Research that have the potential to further our understanding of issues surrounding underrepresentation. These efforts include research into (1) the role of community and strategies for developing effective communities; (2) physics identity and self-efficacy; (3) the affordances that students from underrepresented groups bring to physics learning; (4) socioeconomics and its impact on mathematization. One of the challenges to conducting this research is the relatively small proportion of underrepresented minority students in current physics classes, and the small number of women in physics and engineering majors. In collaboration with Stephen Kanim, New Mexico State University.

  5. Organ donation and Islam-challenges and opportunities.

    Science.gov (United States)

    Sharif, Adnan

    2012-09-15

    The issue of organ donation in Islam has been debated for decades, with most religious authorities sanctioning both living-organ and deceased-organ donation. However, disquiet among the Islamic community on the compatibility of organ donation with their faith remains, especially in relation to deceased-organ donation. This remains a topical, controversial, and challenging component of organ procurement at both local and international levels. In this article, I will explore Islamic arguments both for and against organ donation, in the context of both living-donor and deceased-donor models. By discussing both practical and philosophical perspectives, the aim is to facilitate discussion on how best to achieve consensus on this issue by driving the debate forward in an open and all-encompassing manner. Although every attempt should be made to achieve consensus among key Muslim opinion makers (individuals, authorities, and institutions), encouraging personalized decision making by intellectual effort should be the goal to achieve genuine informed consent.

  6. Data science and symbolic AI: Synergies, challenges and opportunities

    KAUST Repository

    Hoehndorf, Robert; Queralt-Rosinach, Nú ria

    2017-01-01

    Symbolic approaches to artificial intelligence represent things within a domain of knowledge through physical symbols, combine symbols into symbol expressions, and manipulate symbols and symbol expressions through inference processes. While a large part of Data Science relies on statistics and applies statistical approaches to artificial intelligence, there is an increasing potential for successfully applying symbolic approaches as well. Symbolic representations and symbolic inference are close to human cognitive representations and therefore comprehensible and interpretable; they are widely used to represent data and metadata, and their specific semantic content must be taken into account for analysis of such information; and human communication largely relies on symbols, making symbolic representations a crucial part in the analysis of natural language. Here we discuss the role symbolic representations and inference can play in Data Science, highlight the research challenges from the perspective of the data scientist, and argue that symbolic methods should become a crucial component of the data scientists’ toolbox.

  7. Fiber Bragg grating sensor interrogators on chip: challenges and opportunities

    Science.gov (United States)

    Marin, Yisbel; Nannipieri, Tiziano; Oton, Claudio J.; Di Pasquale, Fabrizio

    2017-04-01

    In this paper we present an overview of the current efforts towards integration of Fiber Bragg Grating (FBG) sensor interrogators. Different photonic integration platforms will be discussed, including monolithic planar lightwave circuit technology, silicon on insulator (SOI), indium phosphide (InP) and gallium arsenide (GaAs) material platforms. Also various possible techniques for wavelength metering and methods for FBG multiplexing will be discussed and compared in terms of resolution, dynamic performance, multiplexing capabilities and reliability. The use of linear filters, array waveguide gratings (AWG) as multiple linear filters and AWG based centroid signal processing techniques will be addressed as well as interrogation techniques based on tunable micro-ring resonators and Mach-Zehnder interferometers (MZI) for phase sensitive detection. The paper will also discuss the challenges and perspectives of photonic integration to address the increasing requirements of several industrial applications.

  8. Emerging Markets for Renewable Energy Certificates: Opportunities and Challenges

    Energy Technology Data Exchange (ETDEWEB)

    Holt, E.; Bird, L.

    2005-01-01

    Renewable energy certificates (RECs) represent the attributes of electricity generated from renewable energy sources. These attributes are unbundled from the physical electricity, and the two products-the attributes embodied in the certificates and the commodity electricity-may be sold or traded separately. RECs are quickly becoming the currency of renewable energy markets because of their flexibility and the fact that they are not subject to the geographic and physical limitations of commodity electricity. RECs are currently used by utilities and marketers to supply renewable energy products to end-use customers as well as to demonstrate compliance with regulatory requirements, such as renewable energy mandates. The purpose of this report is to describe and analyze the emerging market for renewable energy certificates. It describes how RECs are marketed, examines RECs markets including scope and prices, and identifies and describes the key challenges facing the growth and success of RECs markets.

  9. Frontiers, Opportunities and Challenges for a Hydrogen Economy

    Science.gov (United States)

    Turner, John

    2015-03-01

    Energy carriers are the staple for powering the society we live in. Coal, oil, natural gas, gasoline and diesel all carry energy in chemical bonds, used in almost all areas of our civilization. But these carriers have a limited-use lifetime on this planet. They are finite, contribute to climate change and carry significant geopolitical issues. If mankind is to maintain and grow our societies, new energy carriers must be developed and deployed into our energy infrastructure. Hydrogen is the simplest of all the energy carriers and when refined from water using renewable energies like solar and wind, represents a sustainable energy carrier, viable for millennia to come. This talk with discuss the challenges for sustainable production of hydrogen, along with the promise and possible pathways for implementing hydrogen into our energy infrastructure.

  10. User Privacy and Empowerment: Trends, Challenges, and Opportunities

    DEFF Research Database (Denmark)

    Dhotre, Prashant Shantaram; Olesen, Henning; Khajuria, Samant

    2018-01-01

    to the service providers. Considering business models that are slanted towards service provid-ers, privacy has become a crucial issue in today’s fast growing digital world. Hence, this paper elaborates personal information flow between users, service providers, and data brokers. We also discussed the significant...... privacy issues like present business models, user awareness about privacy and user control over per-sonal data. To address such issues, this paper also identified challenges that com-prise unavailability of effective privacy awareness or protection tools and the ef-fortless way to study and see the flow...... of personal information and its manage-ment. Thus, empowering users and enhancing awareness are essential to compre-hending the value of secrecy. This paper also introduced latest advances in the domain of privacy issues like User Managed Access (UMA) can state suitable requirements for user empowerment...

  11. Deceased organ donation for transplantation: Challenges and opportunities

    Science.gov (United States)

    Girlanda, Raffaele

    2016-01-01

    Organ transplantation saves thousands of lives every year but the shortage of donors is a major limiting factor to increase transplantation rates. To allow more patients to be transplanted before they die on the wait-list an increase in the number of donors is necessary. Patients with devastating irreversible brain injury, if medically suitable, are potential deceased donors and strategies are needed to successfully convert them into actual donors. Multiple steps in the process of deceased organ donation can be targeted to increase the number of organs suitable for transplant. In this review, after describing this process, we discuss current challenges and potential strategies to expand the pool of deceased donors. PMID:27683626

  12. Managing the cigeo design: a challenge and an opportunity

    International Nuclear Information System (INIS)

    Muscetti, R.

    2015-01-01

    INGEROP is working since years on the French Deep Geological Repository's design for Andra, carrying out since 2012 the preliminary design, the global project management and the technical integration for the engineering of the Cigeo project (in a 50-50 consortium with the French company TECHNIP). The article presents some particular organizational aspects that turned out to be more challenging than foreseen in the course of our activities. Starting from the presentation of real examples, some lessons learned are derived as well as practices of interest in solving analogue issues in similar projects, with focus on its application to the management of engineering phase of geological repositories and other 'megaprojects' in different countries. (author)

  13. Anaerobic digestion of food waste - Challenges and opportunities.

    Science.gov (United States)

    Xu, Fuqing; Li, Yangyang; Ge, Xumeng; Yang, Liangcheng; Li, Yebo

    2018-01-01

    The disposal of large amounts of food waste has caused significant environmental pollution and financial costs globally. Compared with traditional disposal methods (i.e., landfilling, incineration, and composting), anaerobic digestion (AD) is a promising technology for food waste management, but has not yet been fully applied due to a few technical and social challenges. This paper summarizes the quantity, composition, and methane potential of various types of food waste. Recent research on different strategies to enhance AD of food waste, including co-digestion, addition of micronutrients, control of foaming, and process design, is discussed. It is envisaged that AD of food waste could be combined with an existing AD facility or be integrated with the production of value-added products to reduce costs and increase revenue. Further understanding of the fundamental biological and physicochemical processes in AD is required to improve the technology. Copyright © 2017 Elsevier Ltd. All rights reserved.

  14. Oral rabies vaccination in north america: opportunities, complexities, and challenges.

    Directory of Open Access Journals (Sweden)

    Dennis Slate

    Full Text Available Steps to facilitate inter-jurisdictional collaboration nationally and continentally have been critical for implementing and conducting coordinated wildlife rabies management programs that rely heavily on oral rabies vaccination (ORV. Formation of a national rabies management team has been pivotal for coordinated ORV programs in the United States of America. The signing of the North American Rabies Management Plan extended a collaborative framework for coordination of surveillance, control, and research in border areas among Canada, Mexico, and the US. Advances in enhanced surveillance have facilitated sampling of greater scope and intensity near ORV zones for improved rabies management decision-making in real time. The value of enhanced surveillance as a complement to public health surveillance was best illustrated in Ohio during 2007, where 19 rabies cases were detected that were critical for the formulation of focused contingency actions for controlling rabies in this strategically key area. Diverse complexities and challenges are commonplace when applying ORV to control rabies in wild meso-carnivores. Nevertheless, intervention has resulted in notable successes, including the elimination of an arctic fox (Vulpes lagopus rabies virus variant in most of southern Ontario, Canada, with ancillary benefits of elimination extending into Quebec and the northeastern US. Progress continues with ORV toward preventing the spread and working toward elimination of a unique variant of gray fox (Urocyon cinereoargenteus rabies in west central Texas. Elimination of rabies in coyotes (Canis latrans through ORV contributed to the US being declared free of canine rabies in 2007. Raccoon (Procyon lotor rabies control continues to present the greatest challenges among meso-carnivore rabies reservoirs, yet to date intervention has prevented this variant from gaining a broad geographic foothold beyond ORV zones designed to prevent its spread from the eastern US

  15. Coal and clean coal technology: challenges and opportunities

    Energy Technology Data Exchange (ETDEWEB)

    Minchener, Andrew [IEA Clean Coal Centre, London (United Kingdom)

    2013-07-01

    Globally, there is a growing concern about fuel diversity and security of supply, particularly with regard to oil and natural gas. In contrast, coal is available from a much wider range of sources and has greater price stability. Consequently, coal use is increasing rapidly, and by 2030 may well reach a level of more than 4,500 Mtoe, corresponding to close to a doubling of current levels. However, at the same time, tightening regulations will require better solutions for achieving environmental compliance, for which coal has a number of key issues to address. Most of the coal will be used in the power generation sector. Consequently, the key research challenges are to develop and deploy methods by which coal can be used cleanly, efficiently, and in a sustainable way. These include improvements to existing coal utilisation technologies, particularly to improve operational flexibility and availability, while reducing energy use through higher efficiencies. There is an increasing need to ensure improved emissions control, with the emphasis on achieving ever-lower emissions of particulates, SO{sub 2} and NO{sub x} while also introducing control of trace species, particularly mercury. Alongside this, a key challenge is the integration of techniques that can capture CO{sub 2} then transport and store it within secure geological formations, thereby resulting in near zero emissions of CO{sub 2}. From a power plant perspective, the need is to achieve such integration while minimising any adverse impact on power plant efficiency, performance of existing emissions control systems, operational flexibility and availability. At the same time, means to minimize the additional costs associated with such technology must be established.

  16. Induced pluripotent stem cells: Challenges and opportunities for cancer immunotherapy

    Directory of Open Access Journals (Sweden)

    Patty eSachamitr

    2014-04-01

    Full Text Available Despite recent advances in cancer treatment over the past 30 years, therapeutic options remain limited and do not always offer a cure for malignancy. Given that tumour associated antigens (TAA are, by definition, self-proteins, the need to productively engage autoreactive T cells remains at the heart of strategies for cancer immunotherapy. These have traditionally focussed on the administration of autologous monocyte-derived dendritic cells (moDC pulsed with TAA, or the ex vivo expansion and adoptive transfer of tumour infiltrating lymphocytes (TIL as a source of TAA-specific cytotoxic T cells (CTL. Although such approaches have shown some efficacy, success has been limited by the poor capacity of moDC to cross-present exogenous TAA to the CD8+ T cell repertoire and the potential for exhaustion of CTL expanded ex vivo. Recent advances in induced pluripotency offer opportunities to generate patient-specific stem cell lines with the potential to differentiate in vitro into cell types whose properties may help address these issues. Here we review recent success in the differentiation of NK cells from human induced pluripotent stem (iPS cells as well as minor subsets of DC with therapeutic potential, including CD141+XCR1+ DC, capable of cross-presenting TAA to naïve CD8+ T cells. Furthermore, we review recent progress in the use of TIL as the starting material for the derivation of iPSC lines, thereby capturing their antigen specificity in a self-renewing stem cell line, from which potentially unlimited numbers of naïve TAA-specific T cells may be differentiated, free of the risks of exhaustion.

  17. Urban River Restoration in Tehran: Challenges and Opportunities

    Science.gov (United States)

    Azizi, S.; Mousavi, H.; Farshad, F.; Hoseinzade Vahedi, N.; Zanjanian, M.; Khamesi, A.; Shojaee, M.; Safdarnejad, S. M.; Mirrahimi, H.; Ahmari, N.

    2015-12-01

    The typical treatment of urban river streams in Tehran has been limited channelization over the last 30 years. Changes in stream hydrology resulting from urbanization causes a widening gap between river and neighborhoods that results in the ecological and visual division between built and natural environments. To address these problems, a new management perspective in Tehran municipality seeks creating a sequence of thematic green spaces which serve as meeting points for adjacent neighborhoods. Implementation of pilot projects has proved that restoration of urban rivers requires a holistic approach with a range of technologies and tools that contribute to the goal of integrated planning. Currently, our team is working on Darband and Darabad catchments in north east Tehran,to provide opportunities for restoration of natural life in order to improve the amenity, ecology and sustainability of an urban river environment based on 4 key planning principles of: Demonstrating characteristics of the city's unique relationship to the river in the riverfront design; Knowing the river ecosystem and planning for a scale larger than the river front; minimizing new floodplain development; and Providing public access, connections, and recreational uses. This presentation will discuss the process of developing a new integrated GIS-based catchment planning system which helped the City shape its strategic plan for two catchments for the 2015-2030 period through multi-objective and multi-criteria optimization. The strategic plan is expected to enable the city to project the effects of introducing any future development in the catchment area on the river system, helping it to prevent such development activities which can have unintended long-term impacts.

  18. Induced pluripotent stem cells: challenges and opportunities for cancer immunotherapy.

    Science.gov (United States)

    Sachamitr, Patty; Hackett, Simon; Fairchild, Paul Jonathan

    2014-01-01

    Despite recent advances in cancer treatment over the past 30 years, therapeutic options remain limited and do not always offer a cure for malignancy. Given that tumor-associated antigens (TAA) are, by definition, self-proteins, the need to productively engage autoreactive T cells remains at the heart of strategies for cancer immunotherapy. These have traditionally focused on the administration of autologous monocyte-derived dendritic cells (moDC) pulsed with TAA, or the ex vivo expansion and adoptive transfer of tumor-infiltrating lymphocytes (TIL) as a source of TAA-specific cytotoxic T cells (CTL). Although such approaches have shown some efficacy, success has been limited by the poor capacity of moDC to cross present exogenous TAA to the CD8(+) T-cell repertoire and the potential for exhaustion of CTL expanded ex vivo. Recent advances in induced pluripotency offer opportunities to generate patient-specific stem cell lines with the potential to differentiate in vitro into cell types whose properties may help address these issues. Here, we review recent success in the differentiation of NK cells from human induced pluripotent stem (iPS) cells as well as minor subsets of dendritic cells (DCs) with therapeutic potential, including CD141(+)XCR1(+) DC, capable of cross presenting TAA to naïve CD8(+) T cells. Furthermore, we review recent progress in the use of TIL as the starting material for the derivation of iPSC lines, thereby capturing their antigen specificity in a self-renewing stem cell line, from which potentially unlimited numbers of naïve TAA-specific T cells may be differentiated, free of the risks of exhaustion.

  19. Empowering Patients through Healthcare Technology and Information? The Challenge of becoming a Patient 2.0

    DEFF Research Database (Denmark)

    Brodersen, Søsser Grith Kragh; Lindegaard, Hanne

    2015-01-01

    of themselves appeared in newspapers, and self-management and telecare technologies were seen as ways to change elderly patients practices. Transformation of the traditional healthcare system remains on the agenda, and it continues to challenge the traditional view of the patient role (framed in this article...... on numerical representations of illness (i.e., metrics) than on direct observations of patients. Through ethnographic research in the Danish healthcare sector, we show how this new healthcare vision actually manifests in practice by presenting cases of elderly heart and diabetes patients. Technologies aimed......Abstract: In the mid-2000s, the term Patient 2.0 began to be used to denote a new patient role: empowered patients were expected to engage with various types of information and specific technologies in order to manage their own illnesses. Headlines such as Future patients will take care...

  20. Challenges of information security incident learning: An industrial case study in a Chinese healthcare organization.

    Science.gov (United States)

    He, Ying; Johnson, Chris

    2017-12-01

    Security incidents can have negative impacts on healthcare organizations, and the security of medical records has become a primary concern of the public. However, previous studies showed that organizations had not effectively learned lessons from security incidents. Incident learning as an essential activity in the "follow-up" phase of security incident response lifecycle has long been addressed but not given enough attention. This paper conducted a case study in a healthcare organization in China to explore their current obstacles in the practice of incident learning. We interviewed both IT professionals and healthcare professionals. The results showed that the organization did not have a structured way to gather and redistribute incident knowledge. Incident response was ineffective in cycling incident knowledge back to inform security management. Incident reporting to multiple stakeholders faced a great challenge. In response to this case study, we suggest the security assurance modeling framework to address those obstacles.