WorldWideScience

Sample records for health risk uncertainties

  1. Sources of uncertainty in characterizing health risks from flare emissions

    International Nuclear Information System (INIS)

    Hrudey, S.E.

    2000-01-01

    The assessment of health risks associated with gas flaring was the focus of this paper. Health risk assessments for environmental decision-making includes the evaluation of scientific data to identify hazards and to determine dose-response assessments, exposure assessments and risk characterization. Gas flaring has been the cause for public health concerns in recent years, most notably since 1996 after a published report by the Alberta Research Council. Some of the major sources of uncertainty associated with identifying hazardous contaminants in flare emissions were discussed. Methods to predict human exposures to emitted contaminants were examined along with risk characterization of predicted exposures to several identified contaminants. One of the problems is that elemental uncertainties exist regarding flare emissions which places limitations of the degree of reassurance that risk assessment can provide, but risk assessment can nevertheless offer some guidance to those responsible for flare emissions

  2. Stochastic goal programming based groundwater remediation management under human-health-risk uncertainty

    International Nuclear Information System (INIS)

    Li, Jing; He, Li; Lu, Hongwei; Fan, Xing

    2014-01-01

    Highlights: • We propose an integrated optimal groundwater remediation design approach. • The approach can address stochasticity in carcinogenic risks. • Goal programming is used to make the system approaching to ideal operation and remediation effects. • The uncertainty in slope factor is evaluated under different confidence levels. • Optimal strategies are obtained to support remediation design under uncertainty. - Abstract: An optimal design approach for groundwater remediation is developed through incorporating numerical simulation, health risk assessment, uncertainty analysis and nonlinear optimization within a general framework. Stochastic analysis and goal programming are introduced into the framework to handle uncertainties in real-world groundwater remediation systems. Carcinogenic risks associated with remediation actions are further evaluated at four confidence levels. The differences between ideal and predicted constraints are minimized by goal programming. The approach is then applied to a contaminated site in western Canada for creating a set of optimal remediation strategies. Results from the case study indicate that factors including environmental standards, health risks and technical requirements mutually affected and restricted themselves. Stochastic uncertainty existed in the entire process of remediation optimization, which should to be taken into consideration in groundwater remediation design

  3. Use of quantitative uncertainty analysis for human health risk assessment

    International Nuclear Information System (INIS)

    Duncan, F.L.W.; Gordon, J.W.; Kelly, M.

    1994-01-01

    Current human health risk assessment method for environmental risks typically use point estimates of risk accompanied by qualitative discussions of uncertainty. Alternatively, Monte Carlo simulations may be used with distributions for input parameters to estimate the resulting risk distribution and descriptive risk percentiles. These two techniques are applied for the ingestion of 1,1=dichloroethene in ground water. The results indicate that Monte Carlo simulations provide significantly more information for risk assessment and risk management than do point estimates

  4. Uncertainties in human health risk assessment of environmental contaminants: A review and perspective.

    Science.gov (United States)

    Dong, Zhaomin; Liu, Yanju; Duan, Luchun; Bekele, Dawit; Naidu, Ravi

    2015-12-01

    Addressing uncertainties in human health risk assessment is a critical issue when evaluating the effects of contaminants on public health. A range of uncertainties exist through the source-to-outcome continuum, including exposure assessment, hazard and risk characterisation. While various strategies have been applied to characterising uncertainty, classical approaches largely rely on how to maximise the available resources. Expert judgement, defaults and tools for characterising quantitative uncertainty attempt to fill the gap between data and regulation requirements. The experiences of researching 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) illustrated uncertainty sources and how to maximise available information to determine uncertainties, and thereby provide an 'adequate' protection to contaminant exposure. As regulatory requirements and recurring issues increase, the assessment of complex scenarios involving a large number of chemicals requires more sophisticated tools. Recent advances in exposure and toxicology science provide a large data set for environmental contaminants and public health. In particular, biomonitoring information, in vitro data streams and computational toxicology are the crucial factors in the NexGen risk assessment, as well as uncertainties minimisation. Although in this review we cannot yet predict how the exposure science and modern toxicology will develop in the long-term, current techniques from emerging science can be integrated to improve decision-making. Copyright © 2015 Elsevier Ltd. All rights reserved.

  5. Uncertainties of nanotechnology: environmental and health risks

    International Nuclear Information System (INIS)

    Delgado Ramos, Giancarlo

    2007-01-01

    The nanotechnology, as any leading edge technology, develops in the border of the unknown thing and, as such, it provokes a degree of uncertainty. On having manipulated the matter to a nanometric scale (thousand millionth of a meter), the potential risks suggest to be not only relatively unpredictable, but also imperceptible to our senses. In such a tenor, evaluating the eventual implications of the nanotechnological progress is a very complex task. And even more if we take into consideration all ethic, legal, socioeconomic, environmental and health issues. The present article evaluates studies and discourses related to promises about the use of nanostructures and their environmental impact. It also treats health impact by evaluating nanotechnology to medicine application, nano make-up and new cancer treatment.

  6. Health risks of climate change: An assessment of uncertainties and its implications for adaption policies

    NARCIS (Netherlands)

    Wardekker, J.A.; de Jong, A.; van Bree, L.; Turkenburg, W.C.; van der Sluijs, J.P.

    2012-01-01

    Background: Projections of health risks of climate change are surrounded with uncertainties in knowledge. Understanding of these uncertainties will help the selection of appropriate adaptation policies. Methods: We made an inventory of conceivable health impacts of climate change, explored the type

  7. Health risks of climate change: An assessment of uncertainties and its implications for adaptation policies

    Science.gov (United States)

    2012-01-01

    Background Projections of health risks of climate change are surrounded with uncertainties in knowledge. Understanding of these uncertainties will help the selection of appropriate adaptation policies. Methods We made an inventory of conceivable health impacts of climate change, explored the type and level of uncertainty for each impact, and discussed its implications for adaptation policy. A questionnaire-based expert elicitation was performed using an ordinal scoring scale. Experts were asked to indicate the level of precision with which health risks can be estimated, given the present state of knowledge. We assessed the individual scores, the expertise-weighted descriptive statistics, and the argumentation given for each score. Suggestions were made for how dealing with uncertainties could be taken into account in climate change adaptation policy strategies. Results The results showed that the direction of change could be indicated for most anticipated health effects. For several potential effects, too little knowledge exists to indicate whether any impact will occur, or whether the impact will be positive or negative. For several effects, rough ‘order-of-magnitude’ estimates were considered possible. Factors limiting health impact quantification include: lack of data, multi-causality, unknown impacts considering a high-quality health system, complex cause-effect relations leading to multi-directional impacts, possible changes of present-day response-relations, and difficulties in predicting local climate impacts. Participants considered heat-related mortality and non-endemic vector-borne diseases particularly relevant for climate change adaptation. Conclusions For possible climate related health impacts characterised by ignorance, adaptation policies that focus on enhancing the health system’s and society’s capability of dealing with possible future changes, uncertainties and surprises (e.g. through resilience, flexibility, and adaptive capacity) are

  8. Uncertainty Analysis on the Health Risk Caused by a Radiological Terror

    International Nuclear Information System (INIS)

    Jeong, Hyojoon; Hwang, Wontae; Kim, Eunhan; Han, Moonhee

    2010-01-01

    Atmospheric dispersion modeling and uncertainty analysis were carried out support the decision making in case of radiological emergency events. The risk caused by inhalation is highly dependent on air concentrations for radionuclides, therefore air monitoring and dispersion modeling have to be performed carefully to reduce the uncertainty of the health risk assessment for the public. When an intentional release of radioactive materials occurs in an urban area, air quality for radioactive materials in the environment is of great importance to take action for countermeasures and environmental risk assessments. Atmospheric modeling is part of the decision making tasks and that it is particularly important for emergency managers as they often need to take actions quickly on very inadequate information. In this study, we assume an 137 Cs explosion of 50 TBq using RDDs in the metropolitan area of Soul, South Korea. California Puff Model is used to calculate an atmospheric dispersion and transport for 137 Cs, and environmental risk analysis is performed using the Monte Carlo method

  9. An introductory guide to uncertainty analysis in environmental and health risk assessment. Environmental Restoration Program

    International Nuclear Information System (INIS)

    Hammonds, J.S.; Hoffman, F.O.; Bartell, S.M.

    1994-12-01

    This report presents guidelines for evaluating uncertainty in mathematical equations and computer models applied to assess human health and environmental risk. Uncertainty analyses involve the propagation of uncertainty in model parameters and model structure to obtain confidence statements for the estimate of risk and identify the model components of dominant importance. Uncertainty analyses are required when there is no a priori knowledge about uncertainty in the risk estimate and when there is a chance that the failure to assess uncertainty may affect the selection of wrong options for risk reduction. Uncertainty analyses are effective when they are conducted in an iterative mode. When the uncertainty in the risk estimate is intolerable for decision-making, additional data are acquired for the dominant model components that contribute most to uncertainty. This process is repeated until the level of residual uncertainty can be tolerated. A analytical and numerical methods for error propagation are presented along with methods for identifying the most important contributors to uncertainty. Monte Carlo simulation with either Simple Random Sampling (SRS) or Latin Hypercube Sampling (LHS) is proposed as the most robust method for propagating uncertainty through either simple or complex models. A distinction is made between simulating a stochastically varying assessment endpoint (i.e., the distribution of individual risks in an exposed population) and quantifying uncertainty due to lack of knowledge about a fixed but unknown quantity (e.g., a specific individual, the maximally exposed individual, or the mean, median, or 95%-tile of the distribution of exposed individuals). Emphasis is placed on the need for subjective judgement to quantify uncertainty when relevant data are absent or incomplete

  10. Environment and Human Health: The Challenge of Uncertainty in Risk Assessment

    Directory of Open Access Journals (Sweden)

    Alex G. Stewart

    2018-01-01

    Full Text Available High quality and accurate environmental investigations and analysis are essential to any assessment of contamination and to the decision-making process thereafter. Remediation decisions may be focused by health outcomes, whether already present or a predicted risk. The variability inherent in environmental media and analysis can be quantified statistically; uncertainty in models can be reduced by additional research; deep uncertainty exists when environmental or biomedical processes are not understood, or agreed upon, or remain uncharacterized. Deep uncertainty is common where health and environment interact. Determinants of health operate from the individual’s genes to the international level; often several levels act synergistically. We show this in detail for lead (Pb. Pathways, exposure, dose and response also vary, modifying certainty. Multi-disciplinary approaches, built on high-quality environmental investigations, enable the management of complex and uncertain situations. High quality, accurate environmental investigations into pollution issues remain the cornerstone of understanding attributable health outcomes and developing appropriate responses and remediation. However, they are not sufficient on their own, needing careful integration with the wider contexts and stakeholder agendas, without which any response to the environmental assessment may very well founder. Such approaches may benefit more people than any other strategy.

  11. Evaluating the Impact of Contaminant Dilution and Biodegradation in Uncertainty Quantification of Human Health Risk

    Science.gov (United States)

    Zarlenga, Antonio; de Barros, Felipe; Fiori, Aldo

    2016-04-01

    We present a probabilistic framework for assessing human health risk due to groundwater contamination. Our goal is to quantify how physical hydrogeological and biochemical parameters control the magnitude and uncertainty of human health risk. Our methodology captures the whole risk chain from the aquifer contamination to the tap water assumption by human population. The contaminant concentration, the key parameter for the risk estimation, is governed by the interplay between the large-scale advection, caused by heterogeneity and the degradation processes strictly related to the local scale dispersion processes. The core of the hazard identification and of the methodology is the reactive transport model: erratic displacement of contaminant in groundwater, due to the spatial variability of hydraulic conductivity (K), is characterized by a first-order Lagrangian stochastic model; different dynamics are considered as possible ways of biodegradation in aerobic and anaerobic conditions. With the goal of quantifying uncertainty, the Beta distribution is assumed for the concentration probability density function (pdf) model, while different levels of approximation are explored for the estimation of the one-point concentration moments. The information pertaining the flow and transport is connected with a proper dose response assessment which generally involves the estimation of physiological parameters of the exposed population. Human health response depends on the exposed individual metabolism (e.g. variability) and is subject to uncertainty. Therefore, the health parameters are intrinsically a stochastic. As a consequence, we provide an integrated in a global probabilistic human health risk framework which allows the propagation of the uncertainty from multiple sources. The final result, the health risk pdf, is expressed as function of a few relevant, physically-based parameters such as the size of the injection area, the Péclet number, the K structure metrics and

  12. Approach to uncertainty in risk analysis

    Energy Technology Data Exchange (ETDEWEB)

    Rish, W.R.

    1988-08-01

    In the Fall of 1985 EPA's Office of Radiation Programs (ORP) initiated a project to develop a formal approach to dealing with uncertainties encountered when estimating and evaluating risks to human health and the environment. Based on a literature review of modeling uncertainty, interviews with ORP technical and management staff, and input from experts on uncertainty analysis, a comprehensive approach was developed. This approach recognizes by design the constraints on budget, time, manpower, expertise, and availability of information often encountered in ''real world'' modeling. It is based on the observation that in practice risk modeling is usually done to support a decision process. As such, the approach focuses on how to frame a given risk modeling problem, how to use that framing to select an appropriate mixture of uncertainty analyses techniques, and how to integrate the techniques into an uncertainty assessment that effectively communicates important information and insight to decision-makers. The approach is presented in this report. Practical guidance on characterizing and analyzing uncertainties about model form and quantities and on effectively communicating uncertainty analysis results is included. Examples from actual applications are presented.

  13. Approach to uncertainty in risk analysis

    International Nuclear Information System (INIS)

    Rish, W.R.

    1988-08-01

    In the Fall of 1985 EPA's Office of Radiation Programs (ORP) initiated a project to develop a formal approach to dealing with uncertainties encountered when estimating and evaluating risks to human health and the environment. Based on a literature review of modeling uncertainty, interviews with ORP technical and management staff, and input from experts on uncertainty analysis, a comprehensive approach was developed. This approach recognizes by design the constraints on budget, time, manpower, expertise, and availability of information often encountered in ''real world'' modeling. It is based on the observation that in practice risk modeling is usually done to support a decision process. As such, the approach focuses on how to frame a given risk modeling problem, how to use that framing to select an appropriate mixture of uncertainty analyses techniques, and how to integrate the techniques into an uncertainty assessment that effectively communicates important information and insight to decision-makers. The approach is presented in this report. Practical guidance on characterizing and analyzing uncertainties about model form and quantities and on effectively communicating uncertainty analysis results is included. Examples from actual applications are presented

  14. Risk regulation in environment, health and safety : Decision in the face of uncertainty

    Energy Technology Data Exchange (ETDEWEB)

    Ettlinger, L A [The Oxford Group, Baltimore, MD (United States)

    1999-12-01

    Regulations that use or refer to the concept of 'risk' are becoming more popular with both the U.S. Congress and Government agencies -- and are often being challenged in the courts. Proponents of stronger regulation suggest that there are significant threats to life and health that receive little or no attention from both elected officials and regulators, whereas advocates of less intensive government intervention point to regulations that impose high costs with little or no benefit. Usually, both the costs and the benefits are highly uncertain. This paper assumes for the purpose of argument that both proponents and opponents can find many cases where their respective arguments have merit. We also assume that both criticisms of the status quo have a large constituency within the public. If these assumption are valid, then a policy problem is created whereby decision makers are being asked, in the face of significant uncertainty, when to regulate, and at what level of specificity to regulate. The purposes of this paper are to offer some fresh ideas about why these problems arise, shed some light on decision making within the Congress, the regulatory agencies and the courts, and offer some practical steps that could be taken to reform the present system of regulation. Our central observation is that disputes arise as to the efficacy of risk regulations (in the face of uncertainty) because of the difficulties citizens face in determining whether either those who cause risks or those who are responsible for mitigating them are acting in the citizen's best interest. These regulations contain issues which typically deal with subjects containing substantial, unresolvable technical and scientific uncertainties. Because of this inherent uncertainty, the relationships between citizens and regulators, with elected officials in the middle, becomes an especially difficult form of agent relationship. We conclude that the problems associated with this agent relationship are

  15. Risk regulation in environment, health and safety : Decision in the face of uncertainty

    Energy Technology Data Exchange (ETDEWEB)

    Ettlinger, L.A. [The Oxford Group, Baltimore, MD (United States)

    1999-12-01

    Regulations that use or refer to the concept of 'risk' are becoming more popular with both the U.S. Congress and Government agencies -- and are often being challenged in the courts. Proponents of stronger regulation suggest that there are significant threats to life and health that receive little or no attention from both elected officials and regulators, whereas advocates of less intensive government intervention point to regulations that impose high costs with little or no benefit. Usually, both the costs and the benefits are highly uncertain. This paper assumes for the purpose of argument that both proponents and opponents can find many cases where their respective arguments have merit. We also assume that both criticisms of the status quo have a large constituency within the public. If these assumption are valid, then a policy problem is created whereby decision makers are being asked, in the face of significant uncertainty, when to regulate, and at what level of specificity to regulate. The purposes of this paper are to offer some fresh ideas about why these problems arise, shed some light on decision making within the Congress, the regulatory agencies and the courts, and offer some practical steps that could be taken to reform the present system of regulation. Our central observation is that disputes arise as to the efficacy of risk regulations (in the face of uncertainty) because of the difficulties citizens face in determining whether either those who cause risks or those who are responsible for mitigating them are acting in the citizen's best interest. These regulations contain issues which typically deal with subjects containing substantial, unresolvable technical and scientific uncertainties. Because of this inherent uncertainty, the relationships between citizens and regulators, with elected officials in the middle, becomes an especially difficult form of agent relationship. We conclude that the problems associated with this agent

  16. Risk regulation in environment, health and safety : Decision in the face of uncertainty

    International Nuclear Information System (INIS)

    Ettlinger, L.A.

    1999-01-01

    Regulations that use or refer to the concept of 'risk' are becoming more popular with both the U.S. Congress and Government agencies -- and are often being challenged in the courts. Proponents of stronger regulation suggest that there are significant threats to life and health that receive little or no attention from both elected officials and regulators, whereas advocates of less intensive government intervention point to regulations that impose high costs with little or no benefit. Usually, both the costs and the benefits are highly uncertain. This paper assumes for the purpose of argument that both proponents and opponents can find many cases where their respective arguments have merit. We also assume that both criticisms of the status quo have a large constituency within the public. If these assumption are valid, then a policy problem is created whereby decision makers are being asked, in the face of significant uncertainty, when to regulate, and at what level of specificity to regulate. The purposes of this paper are to offer some fresh ideas about why these problems arise, shed some light on decision making within the Congress, the regulatory agencies and the courts, and offer some practical steps that could be taken to reform the present system of regulation. Our central observation is that disputes arise as to the efficacy of risk regulations (in the face of uncertainty) because of the difficulties citizens face in determining whether either those who cause risks or those who are responsible for mitigating them are acting in the citizen's best interest. These regulations contain issues which typically deal with subjects containing substantial, unresolvable technical and scientific uncertainties. Because of this inherent uncertainty, the relationships between citizens and regulators, with elected officials in the middle, becomes an especially difficult form of agent relationship. We conclude that the problems associated with this agent relationship are

  17. Simplified quantitative treatment of uncertainty and interindividual variability in health risk assessment

    International Nuclear Information System (INIS)

    Bogen, K.T.

    1993-01-01

    A distinction between uncertainty (or the extent of lack of knowledge) and interindividual variability (or the extent of person-to-person heterogeneity) regarding the values of input variates must be maintained if a quantitative characterization of uncertainty in population risk or in individual risk is sought. Here, some practical methods are presented that should facilitate implementation of the analytic framework for uncertainty and variability proposed by Bogen and Spear. (1,2) Two types of methodology are discussed: one that facilitates the distinction between uncertainty and variability per se, and another that may be used to simplify quantitative analysis of distributed inputs representing either uncertainty or variability. A simple and a complex form for modeled increased risk are presented and then used to illustrate methods facilitating the distinction between uncertainty and variability in reference to characterization of both population and individual risk. Finally, a simple form of discrete probability calculus is proposed as an easily implemented, practical altemative to Monte-Carlo based procedures to quantitative integration of uncertainty and variability in risk assessment

  18. An introductory guide to uncertainty analysis in environmental and health risk assessment

    International Nuclear Information System (INIS)

    Hoffman, F.O.; Hammonds, J.S.

    1992-10-01

    To compensate for the potential for overly conservative estimates of risk using standard US Environmental Protection Agency methods, an uncertainty analysis should be performed as an integral part of each risk assessment. Uncertainty analyses allow one to obtain quantitative results in the form of confidence intervals that will aid in decision making and will provide guidance for the acquisition of additional data. To perform an uncertainty analysis, one must frequently rely on subjective judgment in the absence of data to estimate the range and a probability distribution describing the extent of uncertainty about a true but unknown value for each parameter of interest. This information is formulated from professional judgment based on an extensive review of literature, analysis of the data, and interviews with experts. Various analytical and numerical techniques are available to allow statistical propagation of the uncertainty in the model parameters to a statement of uncertainty in the risk to a potentially exposed individual. Although analytical methods may be straightforward for relatively simple models, they rapidly become complicated for more involved risk assessments. Because of the tedious efforts required to mathematically derive analytical approaches to propagate uncertainty in complicated risk assessments, numerical methods such as Monte Carlo simulation should be employed. The primary objective of this report is to provide an introductory guide for performing uncertainty analysis in risk assessments being performed for Superfund sites

  19. Uncertainty characterization approaches for risk assessment of DBPs in drinking water: a review.

    Science.gov (United States)

    Chowdhury, Shakhawat; Champagne, Pascale; McLellan, P James

    2009-04-01

    The management of risk from disinfection by-products (DBPs) in drinking water has become a critical issue over the last three decades. The areas of concern for risk management studies include (i) human health risk from DBPs, (ii) disinfection performance, (iii) technical feasibility (maintenance, management and operation) of treatment and disinfection approaches, and (iv) cost. Human health risk assessment is typically considered to be the most important phase of the risk-based decision-making or risk management studies. The factors associated with health risk assessment and other attributes are generally prone to considerable uncertainty. Probabilistic and non-probabilistic approaches have both been employed to characterize uncertainties associated with risk assessment. The probabilistic approaches include sampling-based methods (typically Monte Carlo simulation and stratified sampling) and asymptotic (approximate) reliability analysis (first- and second-order reliability methods). Non-probabilistic approaches include interval analysis, fuzzy set theory and possibility theory. However, it is generally accepted that no single method is suitable for the entire spectrum of problems encountered in uncertainty analyses for risk assessment. Each method has its own set of advantages and limitations. In this paper, the feasibility and limitations of different uncertainty analysis approaches are outlined for risk management studies of drinking water supply systems. The findings assist in the selection of suitable approaches for uncertainty analysis in risk management studies associated with DBPs and human health risk.

  20. Uncertainties in risk assessment at USDOE facilities

    Energy Technology Data Exchange (ETDEWEB)

    Hamilton, L.D.; Holtzman, S.; Meinhold, A.F.; Morris, S.C.; Rowe, M.D.

    1994-01-01

    The United States Department of Energy (USDOE) has embarked on an ambitious program to remediate environmental contamination at its facilities. Decisions concerning cleanup goals, choices among cleanup technologies, and funding prioritization should be largely risk-based. Risk assessments will be used more extensively by the USDOE in the future. USDOE needs to develop and refine risk assessment methods and fund research to reduce major sources of uncertainty in risk assessments at USDOE facilities. The terms{open_quote} risk assessment{close_quote} and{open_quote} risk management{close_quote} are frequently confused. The National Research Council (1983) and the United States Environmental Protection Agency (USEPA, 1991a) described risk assessment as a scientific process that contributes to risk management. Risk assessment is the process of collecting, analyzing and integrating data and information to identify hazards, assess exposures and dose responses, and characterize risks. Risk characterization must include a clear presentation of {open_quotes}... the most significant data and uncertainties...{close_quotes} in an assessment. Significant data and uncertainties are {open_quotes}...those that define and explain the main risk conclusions{close_quotes}. Risk management integrates risk assessment information with other considerations, such as risk perceptions, socioeconomic and political factors, and statutes, to make and justify decisions. Risk assessments, as scientific processes, should be made independently of the other aspects of risk management (USEPA, 1991a), but current methods for assessing health risks are based on conservative regulatory principles, causing unnecessary public concern and misallocation of funds for remediation.

  1. Uncertainties in risk assessment at USDOE facilities

    International Nuclear Information System (INIS)

    Hamilton, L.D.; Holtzman, S.; Meinhold, A.F.; Morris, S.C.; Rowe, M.D.

    1994-01-01

    The United States Department of Energy (USDOE) has embarked on an ambitious program to remediate environmental contamination at its facilities. Decisions concerning cleanup goals, choices among cleanup technologies, and funding prioritization should be largely risk-based. Risk assessments will be used more extensively by the USDOE in the future. USDOE needs to develop and refine risk assessment methods and fund research to reduce major sources of uncertainty in risk assessments at USDOE facilities. The terms open-quote risk assessment close-quote and open-quote risk management close-quote are frequently confused. The National Research Council (1983) and the United States Environmental Protection Agency (USEPA, 1991a) described risk assessment as a scientific process that contributes to risk management. Risk assessment is the process of collecting, analyzing and integrating data and information to identify hazards, assess exposures and dose responses, and characterize risks. Risk characterization must include a clear presentation of open-quotes... the most significant data and uncertainties...close quotes in an assessment. Significant data and uncertainties are open-quotes...those that define and explain the main risk conclusionsclose quotes. Risk management integrates risk assessment information with other considerations, such as risk perceptions, socioeconomic and political factors, and statutes, to make and justify decisions. Risk assessments, as scientific processes, should be made independently of the other aspects of risk management (USEPA, 1991a), but current methods for assessing health risks are based on conservative regulatory principles, causing unnecessary public concern and misallocation of funds for remediation

  2. The Uncertainties of Risk Management

    DEFF Research Database (Denmark)

    Vinnari, Eija; Skærbæk, Peter

    2014-01-01

    for expanding risk management. More generally, such uncertainties relate to the professional identities and responsibilities of operational managers as defined by the framing devices. Originality/value – The paper offers three contributions to the extant literature: first, it shows how risk management itself......Purpose – The purpose of this paper is to analyse the implementation of risk management as a tool for internal audit activities, focusing on unexpected effects or uncertainties generated during its application. Design/methodology/approach – Public and confidential documents as well as semi......-structured interviews are analysed through the lens of actor-network theory to identify the effects of risk management devices in a Finnish municipality. Findings – The authors found that risk management, rather than reducing uncertainty, itself created unexpected uncertainties that would otherwise not have emerged...

  3. Where do uncertainties reside within environmental risk assessments? Expert opinion on uncertainty distributions for pesticide risks to surface water organisms.

    Science.gov (United States)

    Skinner, Daniel J C; Rocks, Sophie A; Pollard, Simon J T

    2016-12-01

    A reliable characterisation of uncertainties can aid uncertainty identification during environmental risk assessments (ERAs). However, typologies can be implemented inconsistently, causing uncertainties to go unidentified. We present an approach based on nine structured elicitations, in which subject-matter experts, for pesticide risks to surface water organisms, validate and assess three dimensions of uncertainty: its level (the severity of uncertainty, ranging from determinism to ignorance); nature (whether the uncertainty is epistemic or aleatory); and location (the data source or area in which the uncertainty arises). Risk characterisation contains the highest median levels of uncertainty, associated with estimating, aggregating and evaluating the magnitude of risks. Regarding the locations in which uncertainty is manifest, data uncertainty is dominant in problem formulation, exposure assessment and effects assessment. The comprehensive description of uncertainty described will enable risk analysts to prioritise the required phases, groups of tasks, or individual tasks within a risk analysis according to the highest levels of uncertainty, the potential for uncertainty to be reduced or quantified, or the types of location-based uncertainty, thus aiding uncertainty prioritisation during environmental risk assessments. In turn, it is expected to inform investment in uncertainty reduction or targeted risk management action. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

  4. Risk uncertainty analysis methods for NUREG-1150

    International Nuclear Information System (INIS)

    Benjamin, A.S.; Boyd, G.J.

    1987-01-01

    Evaluation and display of risk uncertainties for NUREG-1150 constitute a principal focus of the Severe Accident Risk Rebaselining/Risk Reduction Program (SARRP). Some of the principal objectives of the uncertainty evaluation are: (1) to provide a quantitative estimate that reflects, for those areas considered, a credible and realistic range of uncertainty in risk; (2) to rank the various sources of uncertainty with respect to their importance for various measures of risk; and (3) to characterize the state of understanding of each aspect of the risk assessment for which major uncertainties exist. This paper describes the methods developed to fulfill these objectives

  5. Guidance for treatment of variability and uncertainty in ecological risk assessments of contaminated sites

    International Nuclear Information System (INIS)

    1998-06-01

    Uncertainty is a seemingly simple concept that has caused great confusion and conflict in the field of risk assessment. This report offers guidance for the analysis and presentation of variability and uncertainty in ecological risk assessments, an important issue in the remedial investigation and feasibility study processes. This report discusses concepts of probability in terms of variance and uncertainty, describes how these concepts differ in ecological risk assessment from human health risk assessment, and describes probabilistic aspects of specific ecological risk assessment techniques. The report ends with 17 points to consider in performing an uncertainty analysis for an ecological risk assessment of a contaminated site

  6. Uncertainty: lotteries and risk

    OpenAIRE

    Ávalos, Eloy

    2011-01-01

    In this paper we develop the theory of uncertainty in a context where the risks assumed by the individual are measurable and manageable. We primarily use the definition of lottery to formulate the axioms of the individual's preferences, and its representation through the utility function von Neumann - Morgenstern. We study the expected utility theorem and its properties, the paradoxes of choice under uncertainty and finally the measures of risk aversion with monetary lotteries.

  7. Uncertainty quantification in flood risk assessment

    Science.gov (United States)

    Blöschl, Günter; Hall, Julia; Kiss, Andrea; Parajka, Juraj; Perdigão, Rui A. P.; Rogger, Magdalena; Salinas, José Luis; Viglione, Alberto

    2017-04-01

    Uncertainty is inherent to flood risk assessments because of the complexity of the human-water system, which is characterised by nonlinearities and interdependencies, because of limited knowledge about system properties and because of cognitive biases in human perception and decision-making. On top of the uncertainty associated with the assessment of the existing risk to extreme events, additional uncertainty arises because of temporal changes in the system due to climate change, modifications of the environment, population growth and the associated increase in assets. Novel risk assessment concepts are needed that take into account all these sources of uncertainty. They should be based on the understanding of how flood extremes are generated and how they change over time. They should also account for the dynamics of risk perception of decision makers and population in the floodplains. In this talk we discuss these novel risk assessment concepts through examples from Flood Frequency Hydrology, Socio-Hydrology and Predictions Under Change. We believe that uncertainty quantification in flood risk assessment should lead to a robust approach of integrated flood risk management aiming at enhancing resilience rather than searching for optimal defense strategies.

  8. GENERAL RISKS AND UNCERTAINTIES OF REPORTING AND MANAGEMENT REPORTING RISKS

    Directory of Open Access Journals (Sweden)

    CAMELIA I. LUNGU

    2011-04-01

    Full Text Available Purpose: Highlighting risks and uncertainties reporting based on a literature review research. Objectives: The delimitation of risk management models and uncertainties in fundamental research. Research method: Fundamental research study directed to identify the relevant risks’ models presented in entities’ financial statements. Uncertainty is one of the fundamental coordinates of our world. As showed J.K. Galbraith (1978, the world now lives under the age of uncertainty. Moreover, we can say that contemporary society development could be achieved by taking decisions under uncertainty, though, risks. Growing concern for the study of uncertainty, its effects and precautions led to the rather recent emergence of a new science, science of hazards (les cindyniques - l.fr. (Kenvern, 1991. Current analysis of risk are dominated by Beck’s (1992 notion that a risk society now exists whereby we have become more concerned about our impact upon nature than the impact of nature upon us. Clearly, risk permeates most aspects of corporate but also of regular life decision-making and few can predict with any precision the future. The risk is almost always a major variable in real-world corporate decision-making, and managers that ignore it are in a real peril. In these circumstances, a possible answer is assuming financial discipline with an appropriate system of incentives.

  9. The Stock Market: Risk vs. Uncertainty.

    Science.gov (United States)

    Griffitts, Dawn

    2002-01-01

    This economics education publication focuses on the U.S. stock market and the risk and uncertainty that an individual faces when investing in the market. The material explains that risk and uncertainty relate to the same underlying concept randomness. It defines and discusses both concepts and notes that although risk is quantifiable, uncertainty…

  10. Sustainability Risk Evaluation for Large-Scale Hydropower Projects with Hybrid Uncertainty

    Directory of Open Access Journals (Sweden)

    Weiyao Tang

    2018-01-01

    Full Text Available As large-scale hydropower projects are influenced by many factors, risk evaluations are complex. This paper considers a hydropower project as a complex system from the perspective of sustainability risk, and divides it into three subsystems: the natural environment subsystem, the eco-environment subsystem and the socioeconomic subsystem. Risk-related factors and quantitative dimensions of each subsystem are comprehensively analyzed considering uncertainty of some quantitative dimensions solved by hybrid uncertainty methods, including fuzzy (e.g., the national health degree, the national happiness degree, the protection of cultural heritage, random (e.g., underground water levels, river width, and fuzzy random uncertainty (e.g., runoff volumes, precipitation. By calculating the sustainability risk-related degree in each of the risk-related factors, a sustainable risk-evaluation model is built. Based on the calculation results, the critical sustainability risk-related factors are identified and targeted to reduce the losses caused by sustainability risk factors of the hydropower project. A case study at the under-construction Baihetan hydropower station is presented to demonstrate the viability of the risk-evaluation model and to provide a reference for the sustainable risk evaluation of other large-scale hydropower projects.

  11. Risk newsboy: approach for addressing uncertainty in developing action levels and cleanup limits

    International Nuclear Information System (INIS)

    Cooke, Roger; MacDonell, Margaret

    2007-01-01

    Site cleanup decisions involve developing action levels and residual limits for key contaminants, to assure health protection during the cleanup period and into the long term. Uncertainty is inherent in the toxicity information used to define these levels, based on incomplete scientific knowledge regarding dose-response relationships across various hazards and exposures at environmentally relevant levels. This problem can be addressed by applying principles used to manage uncertainty in operations research, as illustrated by the newsboy dilemma. Each day a newsboy must balance the risk of buying more papers than he can sell against the risk of not buying enough. Setting action levels and cleanup limits involves a similar concept of balancing and distributing risks and benefits in the face of uncertainty. The newsboy approach can be applied to develop health-based target concentrations for both radiological and chemical contaminants, with stakeholder input being crucial to assessing 'regret' levels. Associated tools include structured expert judgment elicitation to quantify uncertainty in the dose-response relationship, and mathematical techniques such as probabilistic inversion and iterative proportional fitting. (authors)

  12. Uncertainties in risk assessment and decision making

    International Nuclear Information System (INIS)

    Starzec, Peter; Purucker, Tom; Stewart, Robert

    2008-02-01

    The general concept for risk assessment in accordance with the Swedish model for contaminated soil implies that the toxicological reference value for a given receptor is first back-calculated to a corresponding concentration of a compound in soil and (if applicable) then modified with respect to e.g. background levels, acute toxicity, and factor of safety. This result in a guideline value that is subsequently compared to the observed concentration levels. Many sources of uncertainty exist when assessing whether the risk for a receptor is significant or not. In this study, the uncertainty aspects have been addressed from three standpoints: 1. Uncertainty in the comparison between the level of contamination (source) and a given risk criterion (e.g. a guideline value) and possible implications on subsequent decisions. This type of uncertainty is considered to be most important in situations where a contaminant is expected to be spatially heterogeneous without any tendency to form isolated clusters (hotspots) that can be easily delineated, i.e. where mean values are appropriate to compare to the risk criterion. 2. Uncertainty in spatial distribution of a contaminant. Spatial uncertainty should be accounted for when hotspots are to be delineated and the volume of soil contaminated with levels above a stated decision criterion has to be assessed (quantified). 3. Uncertainty in an ecological exposure model with regard to the moving pattern of a receptor in relation to spatial distribution of contaminant in question. The study points out that the choice of methodology to characterize the relation between contaminant concentration and a pre-defined risk criterion is governed by a conceptual perception of the contaminant's spatial distribution and also depends on the structure of collected data (observations). How uncertainty in transition from contaminant concentration into risk criterion can be quantified was demonstrated by applying hypothesis tests and the concept of

  13. Risk and Uncertainty in Production Economics | Otaha | African ...

    African Journals Online (AJOL)

    One of the most celebrated and feared concepts in the World today are risk which is the product of uncertainty. Risk and uncertainty are often used interchangeably by many economists as if they are the same thing, but it is not true. While risk can be measured and estimated, and even ensured, uncertainty can not.

  14. Risk Assessment Uncertainties in Cybersecurity Investments

    Directory of Open Access Journals (Sweden)

    Andrew Fielder

    2018-06-01

    Full Text Available When undertaking cybersecurity risk assessments, it is important to be able to assign numeric values to metrics to compute the final expected loss that represents the risk that an organization is exposed to due to cyber threats. Even if risk assessment is motivated by real-world observations and data, there is always a high chance of assigning inaccurate values due to different uncertainties involved (e.g., evolving threat landscape, human errors and the natural difficulty of quantifying risk. Existing models empower organizations to compute optimal cybersecurity strategies given their financial constraints, i.e., available cybersecurity budget. Further, a general game-theoretic model with uncertain payoffs (probability-distribution-valued payoffs shows that such uncertainty can be incorporated in the game-theoretic model by allowing payoffs to be random. This paper extends previous work in the field to tackle uncertainties in risk assessment that affect cybersecurity investments. The findings from simulated examples indicate that although uncertainties in cybersecurity risk assessment lead, on average, to different cybersecurity strategies, they do not play a significant role in the final expected loss of the organization when utilising a game-theoretic model and methodology to derive these strategies. The model determines robust defending strategies even when knowledge regarding risk assessment values is not accurate. As a result, it is possible to show that the cybersecurity investments’ tool is capable of providing effective decision support.

  15. Risks, uncertainty, vagueness

    International Nuclear Information System (INIS)

    Haefele, W.; Renn, O.; Erdmann, G.

    1990-01-01

    The notion of 'risk' is discussed in its social and technological contexts, leading to an investigation of the terms factuality, hypotheticality, uncertainty, and vagueness, and to the problems of acceptance and acceptability especially in the context of political decision finding. (DG) [de

  16. Climate policy uncertainty and investment risk

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-06-21

    Our climate is changing. This is certain. Less certain, however, is the timing and magnitude of climate change, and the cost of transition to a low-carbon world. Therefore, many policies and programmes are still at a formative stage, and policy uncertainty is very high. This book identifies how climate change policy uncertainty may affect investment behaviour in the power sector. For power companies, where capital stock is intensive and long-lived, those risks rank among the biggest and can create an incentive to delay investment. Our analysis results show that the risk premiums of climate change uncertainty can add 40% of construction costs of the plant for power investors, and 10% of price surcharges for the electricity end-users. This publication tells what can be done in policy design to reduce these costs. Incorporating the results of quantitative analysis, this publication also shows the sensitivity of different power sector investment decisions to different risks. It compares the effects of climate policy uncertainty with energy market uncertainty, showing the relative importance of these sources of risk for different technologies in different market types. Drawing on extensive consultation with power companies and financial investors, it also assesses the implications for policy makers, allowing the key messages to be transferred into policy designs. This book is a useful tool for governments to improve climate policy mechanisms and create more certainty for power investors.

  17. Consideration of uncertainties in CCDF risk curves in safety oriented decision making processes

    International Nuclear Information System (INIS)

    Stern, E.; Tadmor, J.

    1988-01-01

    In recent years, some of the results of Probabilistic Risk Assessment (i.e. the magnitudes of the various adverse health effects and other effects of potential accidents in nuclear power plants) have usually been presented in Complementary Cumulative Distribution Function curves, widely known as CCDF risk curves. CCDF curves are characteristic of probabilistic accident analyses and consequence calculations, although, in many cases, the codes producing the CCDF curves consist of a mixture of both probabilistic and deterministic calculations. One of the main difficulties in the process of PRA is the problem of uncertainties associated with the risk assessments. The uncertainties, as expressed in CCDF risk curves can be classified into two main categories: (a) uncertainties expressed by the CCDF risk curve itself due to its probabilistic nature and - (b) the uncertainty band of CCDF risk curves. The band consists of a ''family of CCDF curves'' which represents the risks (e.g. early/late fatalities) evaluated at various levels of confidence for a specific Plant-Site Combination (PSC) i.e. a certain nuclear power plant located at a certain site. The reasons why a family of curves rather than a single curve represents the risk of a certain PSC have been discussed. Generally, the uncertainty band of CCDF curves is limited by the 95% (''conservative'') and the 5% curves. In most cases the 50% (median, ''best estimate'') curve is also shown because scientists tend to believe that it represents the ''realistic'' (or real) risk of the plant

  18. Uncertainty in ecological risk assessment: A statistician's view

    International Nuclear Information System (INIS)

    Smith, E.P.

    1995-01-01

    Uncertainty is a topic that has different meanings to researchers, modelers, managers and policy makers. The perspective of this presentation will be on the modeling view of uncertainty and its quantitative assessment. The goal is to provide some insight into how a statistician visualizes and addresses the issue of uncertainty in ecological risk assessment problems. In ecological risk assessment, uncertainty arises from many sources and is of different type depending on what is studies, where it is studied and how it is studied. Some major sources and their impact are described. A variety of quantitative approaches to modeling uncertainty are characterized and a general taxonomy given. Examples of risk assessments of lake acidification, power plant impact assessment and the setting of standards for chemicals will be used discuss approaches to quantitative assessment of uncertainty and some of the potential difficulties

  19. Regulatory uncertainty and the associated business risk for emerging technologies

    International Nuclear Information System (INIS)

    Hoerr, Robert A.

    2011-01-01

    An oversight system specifically concerned with nanomaterials should be flexible enough to take into account the unique aspects of individual novel materials and the settings in which they might be used, while recognizing that heretofore unrecognized safety issues may require future modifications. This article considers a question not explicitly considered by the project team: what is the risk that uncertainty over how regulatory oversight will be applied to nanomaterials will delay or block the development of this emerging technology, thereby depriving human health of potential and substantial benefits? An ambiguous regulatory environment could delay the availability of valuable new technology and therapeutics for human health by reducing access to investment capital. Venture capitalists list regulatory uncertainty as a major reason not to invest at all in certain areas. Uncertainty is far more difficult to evaluate than risk, which lends itself to quantitative models and can be factored into projections of return on possible investments. Loss of time has a large impact on investment return. An examination of regulatory case histories suggests that an increase in regulatory resting requirement, where the path is well-defined, is far less costly than a delay of a year or more in achieving product approval and market launch.

  20. Regulatory uncertainty and the associated business risk for emerging technologies

    Science.gov (United States)

    Hoerr, Robert A.

    2011-04-01

    An oversight system specifically concerned with nanomaterials should be flexible enough to take into account the unique aspects of individual novel materials and the settings in which they might be used, while recognizing that heretofore unrecognized safety issues may require future modifications. This article considers a question not explicitly considered by the project team: what is the risk that uncertainty over how regulatory oversight will be applied to nanomaterials will delay or block the development of this emerging technology, thereby depriving human health of potential and substantial benefits? An ambiguous regulatory environment could delay the availability of valuable new technology and therapeutics for human health by reducing access to investment capital. Venture capitalists list regulatory uncertainty as a major reason not to invest at all in certain areas. Uncertainty is far more difficult to evaluate than risk, which lends itself to quantitative models and can be factored into projections of return on possible investments. Loss of time has a large impact on investment return. An examination of regulatory case histories suggests that an increase in regulatory resting requirement, where the path is well-defined, is far less costly than a delay of a year or more in achieving product approval and market launch.

  1. Analysis of uncertainty in modeling perceived risks

    International Nuclear Information System (INIS)

    Melnyk, R.; Sandquist, G.M.

    2005-01-01

    Expanding on a mathematical model developed for quantifying and assessing perceived risks, the distribution functions, variances, and uncertainties associated with estimating the model parameters are quantified. The analytical model permits the identification and assignment of any number of quantifiable risk perception factors that can be incorporated within standard risk methodology. Those risk perception factors associated with major technical issues are modeled using lognormal probability density functions to span the potentially large uncertainty variations associated with these risk perceptions. The model quantifies the logic of public risk perception and provides an effective means for measuring and responding to perceived risks. (authors)

  2. Developing Hydrogeological Site Characterization Strategies based on Human Health Risk

    Science.gov (United States)

    de Barros, F.; Rubin, Y.; Maxwell, R. M.

    2013-12-01

    In order to provide better sustainable groundwater quality management and minimize the impact of contamination in humans, improved understanding and quantification of the interaction between hydrogeological models, geological site information and human health are needed. Considering the joint influence of these components in the overall human health risk assessment and the corresponding sources of uncertainty aid decision makers to better allocate resources in data acquisition campaigns. This is important to (1) achieve remediation goals in a cost-effective manner, (2) protect human health and (3) keep water supplies clean in order to keep with quality standards. Such task is challenging since a full characterization of the subsurface is unfeasible due to financial and technological constraints. In addition, human exposure and physiological response to contamination are subject to uncertainty and variability. Normally, sampling strategies are developed with the goal of reducing uncertainty, but less often they are developed in the context of their impacts on the overall system uncertainty. Therefore, quantifying the impact from each of these components (hydrogeological, behavioral and physiological) in final human health risk prediction can provide guidance for decision makers to best allocate resources towards minimal prediction uncertainty. In this presentation, a multi-component human health risk-based framework is presented which allows decision makers to set priorities through an information entropy-based visualization tool. Results highlight the role of characteristic length-scales characterizing flow and transport in determining data needs within an integrated hydrogeological-health framework. Conditions where uncertainty reduction in human health risk predictions may benefit from better understanding of the health component, as opposed to a more detailed hydrogeological characterization, are also discussed. Finally, results illustrate how different dose

  3. Risk assessment under deep uncertainty: A methodological comparison

    International Nuclear Information System (INIS)

    Shortridge, Julie; Aven, Terje; Guikema, Seth

    2017-01-01

    Probabilistic Risk Assessment (PRA) has proven to be an invaluable tool for evaluating risks in complex engineered systems. However, there is increasing concern that PRA may not be adequate in situations with little underlying knowledge to support probabilistic representation of uncertainties. As analysts and policy makers turn their attention to deeply uncertain hazards such as climate change, a number of alternatives to traditional PRA have been proposed. This paper systematically compares three diverse approaches for risk analysis under deep uncertainty (qualitative uncertainty factors, probability bounds, and robust decision making) in terms of their representation of uncertain quantities, analytical output, and implications for risk management. A simple example problem is used to highlight differences in the way that each method relates to the traditional risk assessment process and fundamental issues associated with risk assessment and description. We find that the implications for decision making are not necessarily consistent between approaches, and that differences in the representation of uncertain quantities and analytical output suggest contexts in which each method may be most appropriate. Finally, each methodology demonstrates how risk assessment can inform decision making in deeply uncertain contexts, informing more effective responses to risk problems characterized by deep uncertainty. - Highlights: • We compare three diverse approaches to risk assessment under deep uncertainty. • A simple example problem highlights differences in analytical process and results. • Results demonstrate how methodological choices can impact risk assessment results.

  4. Uncertainties in Cancer Risk Coefficients for Environmental Exposure to Radionuclides. An Uncertainty Analysis for Risk Coefficients Reported in Federal Guidance Report No. 13

    Energy Technology Data Exchange (ETDEWEB)

    Pawel, David [U.S. Environmental Protection Agency; Leggett, Richard Wayne [ORNL; Eckerman, Keith F [ORNL; Nelson, Christopher [U.S. Environmental Protection Agency

    2007-01-01

    Federal Guidance Report No. 13 (FGR 13) provides risk coefficients for estimation of the risk of cancer due to low-level exposure to each of more than 800 radionuclides. Uncertainties in risk coefficients were quantified in FGR 13 for 33 cases (exposure to each of 11 radionuclides by each of three exposure pathways) on the basis of sensitivity analyses in which various combinations of plausible biokinetic, dosimetric, and radiation risk models were used to generate alternative risk coefficients. The present report updates the uncertainty analysis in FGR 13 for the cases of inhalation and ingestion of radionuclides and expands the analysis to all radionuclides addressed in that report. The analysis indicates that most risk coefficients for inhalation or ingestion of radionuclides are determined within a factor of 5 or less by current information. That is, application of alternate plausible biokinetic and dosimetric models and radiation risk models (based on the linear, no-threshold hypothesis with an adjustment for the dose and dose rate effectiveness factor) is unlikely to change these coefficients by more than a factor of 5. In this analysis the assessed uncertainty in the radiation risk model was found to be the main determinant of the uncertainty category for most risk coefficients, but conclusions concerning the relative contributions of risk and dose models to the total uncertainty in a risk coefficient may depend strongly on the method of assessing uncertainties in the risk model.

  5. Introduction of risk size in the determination of uncertainty factor UFL in risk assessment

    International Nuclear Information System (INIS)

    Xue Jinling; Lu Yun; Velasquez, Natalia; Hu Hongying; Yu Ruozhen; Liu Zhengtao; Meng Wei

    2012-01-01

    The methodology for using uncertainty factors in health risk assessment has been developed for several decades. A default value is usually applied for the uncertainty factor UF L , which is used to extrapolate from LOAEL (lowest observed adverse effect level) to NAEL (no adverse effect level). Here, we have developed a new method that establishes a linear relationship between UF L and the additional risk level at LOAEL based on the dose–response information, which represents a very important factor that should be carefully considered. This linear formula makes it possible to select UF L properly in the additional risk range from 5.3% to 16.2%. Also the results remind us that the default value 10 may not be conservative enough when the additional risk level at LOAEL exceeds 16.2%. Furthermore, this novel method not only provides a flexible UF L instead of the traditional default value, but also can ensure a conservative estimation of the UF L with fewer errors, and avoid the benchmark response selection involved in the benchmark dose method. These advantages can improve the estimation of the extrapolation starting point in the risk assessment. (letter)

  6. Gambling in Latin: incorporating uncertainty in risk management

    Energy Technology Data Exchange (ETDEWEB)

    Gratt, L.B.; Levin, L. (IWG Corporation, San Diego, CA (United States))

    1994-08-01

    Risk assessment uses assumptions based on differing degrees of conservatism. This complicates the understanding of the uncertainty in the final risk estimate. Uncertainties arise from each component of the risk assessment process: source terms, atmospheric transport, exposure, and dose response. Probabilistic modeling using Monte Carlo and Latin Square sampling techniques (reference to Gambling in Latin) allows for an improved approach to risk assessment and management. 16 refs., 1 fig., 1 tab.

  7. Assessing scenario and parametric uncertainties in risk analysis: a model uncertainty audit

    International Nuclear Information System (INIS)

    Tarantola, S.; Saltelli, A.; Draper, D.

    1999-01-01

    In the present study a process of model audit is addressed on a computational model used for predicting maximum radiological doses to humans in the field of nuclear waste disposal. Global uncertainty and sensitivity analyses are employed to assess output uncertainty and to quantify the contribution of parametric and scenario uncertainties to the model output. These tools are of fundamental importance for risk analysis and decision making purposes

  8. Uncertainties and demonstration of compliance with numerical risk standards

    International Nuclear Information System (INIS)

    Preyssl, C.; Cullingford, M.C.

    1987-01-01

    When dealing with numerical results of a probabilistic risk analysis performed for a complex system, such as a nuclear power plant, one major objective may be to deal with the problem of compliance or non-compliance with a prefixed risk standard. The uncertainties in the risk results associated with the consequences and their probabilities of occurrence may be considered by representing the risk as a risk band. Studying the area and distance between the upper and lower bound of the risk band provides consistent information on the uncertainties in terms of risk, not by means of scalars only but also by real functions. Criteria can be defined for determining compliance with a numerical risk standard, and the 'weighting functional' method, representing a possible tool for testing compliance of risk results, is introduced. By shifting the upper confidence bound due to redefinition, part of the risk band may exceed the standard without changing the underlying results. Using the concept described it is possible to determine the amount of risk, i.e. uncertainty, exceeding the standard. The mathematical treatment of uncertainties therefore allows probabilistic risk assessment results to be compared. A realistic example illustrates the method. (author)

  9. Uncertainty analysis in the applications of nuclear probabilistic risk assessment

    International Nuclear Information System (INIS)

    Le Duy, T.D.

    2011-01-01

    The aim of this thesis is to propose an approach to model parameter and model uncertainties affecting the results of risk indicators used in the applications of nuclear Probabilistic Risk assessment (PRA). After studying the limitations of the traditional probabilistic approach to represent uncertainty in PRA model, a new approach based on the Dempster-Shafer theory has been proposed. The uncertainty analysis process of the proposed approach consists in five main steps. The first step aims to model input parameter uncertainties by belief and plausibility functions according to the data PRA model. The second step involves the propagation of parameter uncertainties through the risk model to lay out the uncertainties associated with output risk indicators. The model uncertainty is then taken into account in the third step by considering possible alternative risk models. The fourth step is intended firstly to provide decision makers with information needed for decision making under uncertainty (parametric and model) and secondly to identify the input parameters that have significant uncertainty contributions on the result. The final step allows the process to be continued in loop by studying the updating of beliefs functions given new data. The proposed methodology was implemented on a real but simplified application of PRA model. (author)

  10. Uncertainty studies and risk assessment for CO2 storage in geological formations

    International Nuclear Information System (INIS)

    Walter, Lena Sophie

    2013-01-01

    Carbon capture and storage (CCS) in deep geological formations is one possible option to mitigate the greenhouse gas effect by reducing CO 2 emissions into the atmosphere. The assessment of the risks related to CO 2 storage is an important task. Events such as CO 2 leakage and brine displacement could result in hazards for human health and the environment. In this thesis, a systematic and comprehensive risk assessment concept is presented to investigate various levels of uncertainties and to assess risks using numerical simulations. Depending on the risk and the processes, which should be assessed, very complex models, large model domains, large time scales, and many simulations runs for estimating probabilities are required. To reduce the resulting high computational costs, a model reduction technique (the arbitrary polynomial chaos expansion) and a method for model coupling in space are applied. The different levels of uncertainties are: statistical uncertainty in parameter distributions, scenario uncertainty, e.g. different geological features, and recognized ignorance due to assumptions in the conceptual model set-up. Recognized ignorance and scenario uncertainty are investigated by simulating well defined model set-ups and scenarios. According to damage values, which are defined as a model output, the set-ups and scenarios can be compared and ranked. For statistical uncertainty probabilities can be determined by running Monte Carlo simulations with the reduced model. The results are presented in various ways: e.g., mean damage, probability density function, cumulative distribution function, or an overall risk value by multiplying the damage with the probability. If the model output (damage) cannot be compared to provided criteria (e.g. water quality criteria), analytical approximations are presented to translate the damage into comparable values. The overall concept is applied for the risks related to brine displacement and infiltration into drinking water

  11. Model uncertainty in financial markets : Long run risk and parameter uncertainty

    NARCIS (Netherlands)

    de Roode, F.A.

    2014-01-01

    Uncertainty surrounding key parameters of financial markets, such as the in- flation and equity risk premium, constitute a major risk for institutional investors with long investment horizons. Hedging the investors’ inflation exposure can be challenging due to the lack of domestic inflation-linked

  12. Assessing uncertainty and risk in exploited marine populations

    International Nuclear Information System (INIS)

    Fogarty, M.J.; Mayo, R.K.; O'Brien, L.; Serchuk, F.M.; Rosenberg, A.A.

    1996-01-01

    The assessment and management of exploited fish and invertebrate populations is subject to several types of uncertainty. This uncertainty translates into risk to the population in the development and implementation of fishery management advice. Here, we define risk as the probability that exploitation rates will exceed a threshold level where long term sustainability of the stock is threatened. We distinguish among several sources of error or uncertainty due to (a) stochasticity in demographic rates and processes, particularly in survival rates during the early fife stages; (b) measurement error resulting from sampling variation in the determination of population parameters or in model estimation; and (c) the lack of complete information on population and ecosystem dynamics. The first represents a form of aleatory uncertainty while the latter two factors represent forms of epistemic uncertainty. To illustrate these points, we evaluate the recent status of the Georges Bank cod stock in a risk assessment framework. Short term stochastic projections are made accounting for uncertainty in population size and for random variability in the number of young surviving to enter the fishery. We show that recent declines in this cod stock can be attributed to exploitation rates that have substantially exceeded sustainable levels

  13. A Framework for Understanding Uncertainty in Seismic Risk Assessment.

    Science.gov (United States)

    Foulser-Piggott, Roxane; Bowman, Gary; Hughes, Martin

    2017-10-11

    A better understanding of the uncertainty that exists in models used for seismic risk assessment is critical to improving risk-based decisions pertaining to earthquake safety. Current models estimating the probability of collapse of a building do not consider comprehensively the nature and impact of uncertainty. This article presents a model framework to enhance seismic risk assessment and thus gives decisionmakers a fuller understanding of the nature and limitations of the estimates. This can help ensure that risks are not over- or underestimated and the value of acquiring accurate data is appreciated fully. The methodology presented provides a novel treatment of uncertainties in input variables, their propagation through the model, and their effect on the results. The study presents ranges of possible annual collapse probabilities for different case studies on buildings in different parts of the world, exposed to different levels of seismicity, and with different vulnerabilities. A global sensitivity analysis was conducted to determine the significance of uncertain variables. Two key outcomes are (1) that the uncertainty in ground-motion conversion equations has the largest effect on the uncertainty in the calculation of annual collapse probability; and (2) the vulnerability of a building appears to have an effect on the range of annual collapse probabilities produced, i.e., the level of uncertainty in the estimate of annual collapse probability, with less vulnerable buildings having a smaller uncertainty. © 2017 Society for Risk Analysis.

  14. Scientific uncertainties associated with risk assessment of radiation

    International Nuclear Information System (INIS)

    Hubert, P.; Fagnani, F.

    1989-05-01

    The proper use and interpretation of data pertaining to biological effects of ionizing radiations is based on a continuous effort to discuss the various assumptions and uncertainties in the process of risk assessment. In this perspective, it has been considered useful by the Committee to review critically the general scientific foundations that constitute the basic framework of data for the evaluation of health effects of radiation. This review is an attempt to identify the main sources of uncertainties, to give, when possible, an order of magnitude for their relative importance, and to clarify the principal interactions between the different steps of the process of risk quantification. The discussion has been restricted to stochastic effects and especially to cancer induction in man: observations at the cellular levels and animal and in vitro experiments have not been considered. The consequences which might result from abandoning the hypothesis of linearity have not been directly examined in this draft, especially in respect to the concept of collective dose. Since another document dealing with 'Dose-response relationships for radiation-induced cancer' is in preparation, an effort has been made to avoid any overlap by making reference to that document whenever necessary

  15. Scientific uncertainties associated with risk assessment of radiation

    Energy Technology Data Exchange (ETDEWEB)

    Hubert, P; Fagnani, F

    1989-05-01

    The proper use and interpretation of data pertaining to biological effects of ionizing radiations is based on a continuous effort to discuss the various assumptions and uncertainties in the process of risk assessment. In this perspective, it has been considered useful by the Committee to review critically the general scientific foundations that constitute the basic framework of data for the evaluation of health effects of radiation. This review is an attempt to identify the main sources of uncertainties, to give, when possible, an order of magnitude for their relative importance, and to clarify the principal interactions between the different steps of the process of risk quantification. The discussion has been restricted to stochastic effects and especially to cancer induction in man: observations at the cellular levels and animal and in vitro experiments have not been considered. The consequences which might result from abandoning the hypothesis of linearity have not been directly examined in this draft, especially in respect to the concept of collective dose. Since another document dealing with 'Dose-response relationships for radiation-induced cancer' is in preparation, an effort has been made to avoid any overlap by making reference to that document whenever necessary.

  16. Methods for Addressing Uncertainty and Variability to Characterize Potential Health Risk From Trichloroethylene-Contaminated Ground Water Beale Air Force Base in California: Integration of Uncertainty and Variability in Pharmacokinetics and Dose-Response; TOPICAL

    International Nuclear Information System (INIS)

    Bogen, K.T.

    1999-01-01

    Traditional estimates of health risk are typically inflated, particularly if cancer is the dominant endpoint and there is fundamental uncertainty as to mechanism(s) of action. Risk is more realistically characterized if it accounts for joint uncertainty and interindividual variability after applying a unified probabilistic approach to the distributed parameters of all (linear as well as nonlinear) risk-extrapolation models involved. Such an approach was applied to characterize risks to potential future residents posed by trichloroethylene (TCE) in ground water at an inactive landfill site on Beale Air Force Base in California. Variability and uncertainty were addressed in exposure-route-specific estimates of applied dose, in pharmacokinetically based estimates of route-specific metabolized fractions of absorbed TCE, and in corresponding biologically effective doses estimated under a genotoxic/linear (MA(sub g)) vs. a cytotoxic/nonlinear (MA(sub c)) mechanistic assumption for TCE-induced cancer. Increased risk conditional on effective dose was estimated under MA(sub G) based on seven rodent-bioassay data sets, and under MA, based on mouse hepatotoxicity data. Mean and upper-bound estimates of combined risk calculated by the unified approach were and lt;10(sup -6) and and lt;10(sup -4), respectively, while corresponding estimates based on traditional deterministic methods were and gt;10(sup -5) and and gt;10(sup -4), respectively. It was estimated that no TCE-related harm is likely occur due any plausible residential exposure scenario involving the site. The unified approach illustrated is particularly suited to characterizing risks that involve uncertain and/or diverse mechanisms of action

  17. Statistically based uncertainty assessments in nuclear risk analysis

    International Nuclear Information System (INIS)

    Spencer, F.W.; Diegert, K.V.; Easterling, R.G.

    1987-01-01

    Over the last decade, the problems of estimation and uncertainty assessment in probabilistics risk assessment (PRAs) have been addressed in a variety of NRC and industry-sponsored projects. These problems have received attention because of a recognition that major uncertainties in risk estimation exist, which can be reduced by collecting more and better data and other information, and because of a recognition that better methods for assessing these uncertainties are needed. In particular, a clear understanding of the nature and magnitude of various sources of uncertainty is needed to facilitate descision-making on possible plant changes and research options. Recent PRAs have employed methods of probability propagation, sometimes involving the use of Bayes Theorem, and intended to formalize the use of ''engineering judgment'' or ''expert opinion.'' All sources, or feelings, of uncertainty are expressed probabilistically, so that uncertainty analysis becomes simply a matter of probability propagation. Alternatives to forcing a probabilistic framework at all stages of a PRA are a major concern in this paper, however

  18. Risk assessment through drinking water pathway via uncertainty modeling of contaminant transport using soft computing

    International Nuclear Information System (INIS)

    Datta, D.; Ranade, A.K.; Pandey, M.; Sathyabama, N.; Kumar, Brij

    2012-01-01

    The basic objective of an environmental impact assessment (EIA) is to build guidelines to reduce the associated risk or mitigate the consequences of the reactor accident at its source to prevent deterministic health effects, to reduce the risk of stochastic health effects (eg. cancer and severe hereditary effects) as much as reasonable achievable by implementing protective actions in accordance with IAEA guidance (IAEA Safety Series No. 115, 1996). The measure of exposure being the basic tool to take any appropriate decisions related to risk reduction, EIA is traditionally expressed in terms of radiation exposure to the member of the public. However, models used to estimate the exposure received by the member of the public are governed by parameters some of which are deterministic with relative uncertainty and some of which are stochastic as well as imprecise (insufficient knowledge). In an admixture environment of this type, it is essential to assess the uncertainty of a model to estimate the bounds of the exposure to the public to invoke a decision during an event of nuclear or radiological emergency. With a view to this soft computing technique such as evidence theory based assessment of model parameters is addressed to compute the risk or exposure to the member of the public. The possible pathway of exposure to the member of the public in the aquatic food stream is the drinking of water. Accordingly, this paper presents the uncertainty analysis of exposure via uncertainty analysis of the contaminated water. Evidence theory finally addresses the uncertainty in terms of lower bound as belief measure and upper bound of exposure as plausibility measure. In this work EIA is presented using evidence theory. Data fusion technique is used to aggregate the knowledge on the uncertain information. Uncertainty of concentration and exposure is expressed as an interval of belief, plausibility

  19. Risk Characterization uncertainties associated description, sensitivity analysis

    International Nuclear Information System (INIS)

    Carrillo, M.; Tovar, M.; Alvarez, J.; Arraez, M.; Hordziejewicz, I.; Loreto, I.

    2013-01-01

    The power point presentation is about risks to the estimated levels of exposure, uncertainty and variability in the analysis, sensitivity analysis, risks from exposure to multiple substances, formulation of guidelines for carcinogenic and genotoxic compounds and risk subpopulations

  20. Hazardous waste transportation risk assessment: Benefits of a combined deterministic and probabilistic Monte Carlo approach in expressing risk uncertainty

    International Nuclear Information System (INIS)

    Policastro, A.J.; Lazaro, M.A.; Cowen, M.A.; Hartmann, H.M.; Dunn, W.E.; Brown, D.F.

    1995-01-01

    This paper presents a combined deterministic and probabilistic methodology for modeling hazardous waste transportation risk and expressing the uncertainty in that risk. Both the deterministic and probabilistic methodologies are aimed at providing tools useful in the evaluation of alternative management scenarios for US Department of Energy (DOE) hazardous waste treatment, storage, and disposal (TSD). The probabilistic methodology can be used to provide perspective on and quantify uncertainties in deterministic predictions. The methodology developed has been applied to 63 DOE shipments made in fiscal year 1992, which contained poison by inhalation chemicals that represent an inhalation risk to the public. Models have been applied to simulate shipment routes, truck accident rates, chemical spill probabilities, spill/release rates, dispersion, population exposure, and health consequences. The simulation presented in this paper is specific to trucks traveling from DOE sites to their commercial TSD facilities, but the methodology is more general. Health consequences are presented as the number of people with potentially life-threatening health effects. Probabilistic distributions were developed (based on actual item data) for accident release amounts, time of day and season of the accident, and meteorological conditions

  1. From risk management to uncertainty management: a significant change in project management

    Institute of Scientific and Technical Information of China (English)

    LI Gui-jun; ZHANG Yue-song

    2006-01-01

    Starting with the meanings of the terms "risk" and "uncertainty,"" he paper compares uncertainty management with risk management in project management. We bring some doubt to the use of "risk" and "uncertainty" interchangeably in project management and deem their scope, methods, responses, monitoring and controlling should be different too. Illustrations are given covering terminology, description, and treatment from different perspectives of uncertainty management and risk management. Furthermore, the paper retains that project risk management (PRM) processes might be modified to facilitate an uncertainty management perspective,and we support that project uncertainty management (PUM) can enlarge its contribution to improving project management performance, which will result in a significant change in emphasis compared with most risk management.

  2. Sensitivity and uncertainty analyses in aging risk-based prioritizations

    International Nuclear Information System (INIS)

    Hassan, M.; Uryas'ev, S.; Vesely, W.E.

    1993-01-01

    Aging risk evaluations of nuclear power plants using Probabilistic Risk Analyses (PRAs) involve assessments of the impact of aging structures, systems, and components (SSCs) on plant core damage frequency (CDF). These assessments can be used to prioritize the contributors to aging risk reflecting the relative risk potential of the SSCs. Aging prioritizations are important for identifying the SSCs contributing most to plant risk and can provide a systematic basis on which aging risk control and management strategies for a plant can be developed. However, these prioritizations are subject to variabilities arising from uncertainties in data, and/or from various modeling assumptions. The objective of this paper is to present an evaluation of the sensitivity of aging prioritizations of active components to uncertainties in aging risk quantifications. Approaches for robust prioritization of SSCs also are presented which are less susceptible to the uncertainties

  3. Methods to Quantify Uncertainty in Human Health Risk Assessment

    National Research Council Canada - National Science Library

    Aurelius, Lea

    1998-01-01

    ...) and other health professionals, such as the Bioenviroumental Engineer, to identify the appropriate use of probabilistic techniques for a site, and the methods by which probabilistic risk assessment...

  4. Political uncertainty and firm risk in China

    Directory of Open Access Journals (Sweden)

    Danglun Luo

    2017-12-01

    Full Text Available The political uncertainty surrounded by the turnover of government officials has a major impact on local economies and local firms. This paper investigates the relationship between the turnover of prefecture-city officials and the inherent risk faced by local firms in China. Using data from 1999 to 2012, we find that prefecture-city official turnovers significantly increased firm risk. Our results show that the political risk was mitigated when new prefecture-city officials were well connected with their provincial leaders. In addition, the impact of political uncertainty was more pronounced for regulated firms and firms residing in provinces with low market openness.

  5. Uncertainty studies and risk assessment for CO{sub 2} storage in geological formations

    Energy Technology Data Exchange (ETDEWEB)

    Walter, Lena Sophie

    2013-07-01

    Carbon capture and storage (CCS) in deep geological formations is one possible option to mitigate the greenhouse gas effect by reducing CO{sub 2} emissions into the atmosphere. The assessment of the risks related to CO{sub 2} storage is an important task. Events such as CO{sub 2} leakage and brine displacement could result in hazards for human health and the environment. In this thesis, a systematic and comprehensive risk assessment concept is presented to investigate various levels of uncertainties and to assess risks using numerical simulations. Depending on the risk and the processes, which should be assessed, very complex models, large model domains, large time scales, and many simulations runs for estimating probabilities are required. To reduce the resulting high computational costs, a model reduction technique (the arbitrary polynomial chaos expansion) and a method for model coupling in space are applied. The different levels of uncertainties are: statistical uncertainty in parameter distributions, scenario uncertainty, e.g. different geological features, and recognized ignorance due to assumptions in the conceptual model set-up. Recognized ignorance and scenario uncertainty are investigated by simulating well defined model set-ups and scenarios. According to damage values, which are defined as a model output, the set-ups and scenarios can be compared and ranked. For statistical uncertainty probabilities can be determined by running Monte Carlo simulations with the reduced model. The results are presented in various ways: e.g., mean damage, probability density function, cumulative distribution function, or an overall risk value by multiplying the damage with the probability. If the model output (damage) cannot be compared to provided criteria (e.g. water quality criteria), analytical approximations are presented to translate the damage into comparable values. The overall concept is applied for the risks related to brine displacement and infiltration into

  6. Farm decision making under risk and uncertainty.

    NARCIS (Netherlands)

    Backus, G.B.C.; Eidman, V.R.; Dijkhuizen, A.A.

    1997-01-01

    Relevant portions of the risk literature are reviewed, relating them to observed behaviour in farm decision-making. Relevant topics for applied agricultural risk research are proposed. The concept of decision making under risk and uncertainty is discussed by reviewing the theory of Subjective

  7. Optimal allocation of resources over health care programmes: dealing with decreasing marginal utility and uncertainty.

    Science.gov (United States)

    Al, Maiwenn J; Feenstra, Talitha L; Hout, Ben A van

    2005-07-01

    This paper addresses the problem of how to value health care programmes with different ratios of costs to effects, specifically when taking into account that these costs and effects are uncertain. First, the traditional framework of maximising health effects with a given health care budget is extended to a flexible budget using a value function over money and health effects. Second, uncertainty surrounding costs and effects is included in the model using expected utility. Other approaches to uncertainty that do not specify a utility function are discussed and it is argued that these also include implicit notions about risk attitude.

  8. Risk, unexpected uncertainty, and estimation uncertainty: Bayesian learning in unstable settings.

    Directory of Open Access Journals (Sweden)

    Elise Payzan-LeNestour

    Full Text Available Recently, evidence has emerged that humans approach learning using Bayesian updating rather than (model-free reinforcement algorithms in a six-arm restless bandit problem. Here, we investigate what this implies for human appreciation of uncertainty. In our task, a Bayesian learner distinguishes three equally salient levels of uncertainty. First, the Bayesian perceives irreducible uncertainty or risk: even knowing the payoff probabilities of a given arm, the outcome remains uncertain. Second, there is (parameter estimation uncertainty or ambiguity: payoff probabilities are unknown and need to be estimated. Third, the outcome probabilities of the arms change: the sudden jumps are referred to as unexpected uncertainty. We document how the three levels of uncertainty evolved during the course of our experiment and how it affected the learning rate. We then zoom in on estimation uncertainty, which has been suggested to be a driving force in exploration, in spite of evidence of widespread aversion to ambiguity. Our data corroborate the latter. We discuss neural evidence that foreshadowed the ability of humans to distinguish between the three levels of uncertainty. Finally, we investigate the boundaries of human capacity to implement Bayesian learning. We repeat the experiment with different instructions, reflecting varying levels of structural uncertainty. Under this fourth notion of uncertainty, choices were no better explained by Bayesian updating than by (model-free reinforcement learning. Exit questionnaires revealed that participants remained unaware of the presence of unexpected uncertainty and failed to acquire the right model with which to implement Bayesian updating.

  9. New challenges on uncertainty propagation assessment of flood risk analysis

    Science.gov (United States)

    Martins, Luciano; Aroca-Jiménez, Estefanía; Bodoque, José M.; Díez-Herrero, Andrés

    2016-04-01

    Natural hazards, such as floods, cause considerable damage to the human life, material and functional assets every year and around the World. Risk assessment procedures has associated a set of uncertainties, mainly of two types: natural, derived from stochastic character inherent in the flood process dynamics; and epistemic, that are associated with lack of knowledge or the bad procedures employed in the study of these processes. There are abundant scientific and technical literature on uncertainties estimation in each step of flood risk analysis (e.g. rainfall estimates, hydraulic modelling variables); but very few experience on the propagation of the uncertainties along the flood risk assessment. Therefore, epistemic uncertainties are the main goal of this work, in particular,understand the extension of the propagation of uncertainties throughout the process, starting with inundability studies until risk analysis, and how far does vary a proper analysis of the risk of flooding. These methodologies, such as Polynomial Chaos Theory (PCT), Method of Moments or Monte Carlo, are used to evaluate different sources of error, such as data records (precipitation gauges, flow gauges...), hydrologic and hydraulic modelling (inundation estimation), socio-demographic data (damage estimation) to evaluate the uncertainties propagation (UP) considered in design flood risk estimation both, in numerical and cartographic expression. In order to consider the total uncertainty and understand what factors are contributed most to the final uncertainty, we used the method of Polynomial Chaos Theory (PCT). It represents an interesting way to handle to inclusion of uncertainty in the modelling and simulation process. PCT allows for the development of a probabilistic model of the system in a deterministic setting. This is done by using random variables and polynomials to handle the effects of uncertainty. Method application results have a better robustness than traditional analysis

  10. Risk Management and Uncertainty in Infrastructure Projects

    DEFF Research Database (Denmark)

    Harty, Chris; Neerup Themsen, Tim; Tryggestad, Kjell

    2014-01-01

    The assumption that large complex projects should be managed in order to reduce uncertainty and increase predictability is not new. What is relatively new, however, is that uncertainty reduction can and should be obtained through formal risk management approaches. We question both assumptions...... by addressing a more fundamental question about the role of knowledge in current risk management practices. Inquiries into the predominant approaches to risk management in large infrastructure and construction projects reveal their assumptions about knowledge and we discuss the ramifications these have...... for project and construction management. Our argument and claim is that predominant risk management approaches tends to reinforce conventional ideas of project control whilst undermining other notions of value and relevance of built assets and project management process. These approaches fail to consider...

  11. Risk Aversion, Price Uncertainty and Irreversible Investments

    NARCIS (Netherlands)

    van den Goorbergh, R.W.J.; Huisman, K.J.M.; Kort, P.M.

    2003-01-01

    This paper generalizes the theory of irreversible investment under uncertainty by allowing for risk averse investors in the absence of com-plete markets.Until now this theory has only been developed in the cases of risk neutrality, or risk aversion in combination with complete markets.Within a

  12. The explicit treatment of model uncertainties in the presence of aleatory and epistemic parameter uncertainties in risk and reliability analysis

    International Nuclear Information System (INIS)

    Ahn, Kwang Il; Yang, Joon Eon

    2003-01-01

    In the risk and reliability analysis of complex technological systems, the primary concern of formal uncertainty analysis is to understand why uncertainties arise, and to evaluate how they impact the results of the analysis. In recent times, many of the uncertainty analyses have focused on parameters of the risk and reliability analysis models, whose values are uncertain in an aleatory or an epistemic way. As the field of parametric uncertainty analysis matures, however, more attention is being paid to the explicit treatment of uncertainties that are addressed in the predictive model itself as well as the accuracy of the predictive model. The essential steps for evaluating impacts of these model uncertainties in the presence of parameter uncertainties are to determine rigorously various sources of uncertainties to be addressed in an underlying model itself and in turn model parameters, based on our state-of-knowledge and relevant evidence. Answering clearly the question of how to characterize and treat explicitly the forgoing different sources of uncertainty is particularly important for practical aspects such as risk and reliability optimization of systems as well as more transparent risk information and decision-making under various uncertainties. The main purpose of this paper is to provide practical guidance for quantitatively treating various model uncertainties that would often be encountered in the risk and reliability modeling process of complex technological systems

  13. Exploring the uncertainties in cancer risk assessment using the integrated probabilistic risk assessment (IPRA) approach.

    Science.gov (United States)

    Slob, Wout; Bakker, Martine I; Biesebeek, Jan Dirk Te; Bokkers, Bas G H

    2014-08-01

    Current methods for cancer risk assessment result in single values, without any quantitative information on the uncertainties in these values. Therefore, single risk values could easily be overinterpreted. In this study, we discuss a full probabilistic cancer risk assessment approach in which all the generally recognized uncertainties in both exposure and hazard assessment are quantitatively characterized and probabilistically evaluated, resulting in a confidence interval for the final risk estimate. The methodology is applied to three example chemicals (aflatoxin, N-nitrosodimethylamine, and methyleugenol). These examples illustrate that the uncertainty in a cancer risk estimate may be huge, making single value estimates of cancer risk meaningless. Further, a risk based on linear extrapolation tends to be lower than the upper 95% confidence limit of a probabilistic risk estimate, and in that sense it is not conservative. Our conceptual analysis showed that there are two possible basic approaches for cancer risk assessment, depending on the interpretation of the dose-incidence data measured in animals. However, it remains unclear which of the two interpretations is the more adequate one, adding an additional uncertainty to the already huge confidence intervals for cancer risk estimates. © 2014 Society for Risk Analysis.

  14. Assessment of Risks and Uncertainties in Poultry Farming in Kwara ...

    African Journals Online (AJOL)

    , identify the risks and uncertainties encountered by the farmers, determines the level of severity of the risks and uncertainties, and identifies the coping strategies employed by the farmers. Primary data obtained from 99 registered poultry ...

  15. Reducing uncertainty in wind turbine blade health inspection with image processing techniques

    Science.gov (United States)

    Zhang, Huiyi

    Structural health inspection has been widely applied in the operation of wind farms to find early cracks in wind turbine blades (WTBs). Increased numbers of turbines and expanded rotor diameters are driving up the workloads and safety risks for site employees. Therefore, it is important to automate the inspection process as well as minimize the uncertainties involved in routine blade health inspection. In addition, crack documentation and trending is vital to assess rotor blade and turbine reliability in the 20 year designed life span. A new crack recognition and classification algorithm is described that can support automated structural health inspection of the surface of large composite WTBs. The first part of the study investigated the feasibility of digital image processing in WTB health inspection and defined the capability of numerically detecting cracks as small as hairline thickness. The second part of the study identified and analyzed the uncertainty of the digital image processing method. A self-learning algorithm was proposed to recognize and classify cracks without comparing a blade image to a library of crack images. The last part of the research quantified the uncertainty in the field conditions and the image processing methods.

  16. Introduction to risk and uncertainty in hydrosystem engineering

    CERN Document Server

    Goodarzi, Ehsan; Teang Shui, Lee

    2013-01-01

    Water engineers require knowledge of stochastic, frequency concepts, uncertainty analysis, risk assessment, and the processes that predict unexpected events. This book presents the basics of stochastic, risk and uncertainty analysis, and random sampling techniques in conjunction with straightforward examples which are solved step by step. In addition, appropriate Excel functions are included as an alternative to solve the examples, and two real case studies is presented in the last chapters of book.

  17. Uncertainties in fatal cancer risk estimates used in radiation protection

    International Nuclear Information System (INIS)

    Kai, Michiaki

    1999-01-01

    Although ICRP and NCRP had not described the details of uncertainties in cancer risk estimates in radiation protection, NCRP, in 1997, firstly reported the results of uncertainty analysis (NCRP No.126) and which is summarized in this paper. The NCRP report pointed out that there are following five factors which uncertainty possessing: uncertainty in epidemiological studies, in dose assessment, in transforming the estimates to risk assessment, in risk prediction and in extrapolation to the low dose/dose rate. These individual factors were analyzed statistically to obtain the relationship between the probability of cancer death in the US population and life time risk coefficient (% per Sv), which showed that, for the latter, the mean value was 3.99 x 10 -2 /Sv, median, 3.38 x 10 -2 /Sv, GSD (geometrical standard deviation), 1.83 x 10 -2 /Sv and 95% confidential limit, 1.2-8.84 x 10 -2 /Sv. The mean value was smaller than that of ICRP recommendation (5 x 10 -2 /Sv), indicating that the value has the uncertainty factor of 2.5-3. Moreover, the most important factor was shown to be the uncertainty in DDREF (dose/dose rate reduction factor). (K.H.)

  18. Assessment and uncertainty analysis of groundwater risk.

    Science.gov (United States)

    Li, Fawen; Zhu, Jingzhao; Deng, Xiyuan; Zhao, Yong; Li, Shaofei

    2018-01-01

    Groundwater with relatively stable quantity and quality is commonly used by human being. However, as the over-mining of groundwater, problems such as groundwater funnel, land subsidence and salt water intrusion have emerged. In order to avoid further deterioration of hydrogeological problems in over-mining regions, it is necessary to conduct the assessment of groundwater risk. In this paper, risks of shallow and deep groundwater in the water intake area of the South-to-North Water Transfer Project in Tianjin, China, were evaluated. Firstly, two sets of four-level evaluation index system were constructed based on the different characteristics of shallow and deep groundwater. Secondly, based on the normalized factor values and the synthetic weights, the risk values of shallow and deep groundwater were calculated. Lastly, the uncertainty of groundwater risk assessment was analyzed by indicator kriging method. The results meet the decision maker's demand for risk information, and overcome previous risk assessment results expressed in the form of deterministic point estimations, which ignore the uncertainty of risk assessment. Copyright © 2017 Elsevier Inc. All rights reserved.

  19. Review of studies related to uncertainty in risk analsis

    International Nuclear Information System (INIS)

    Rish, W.R.; Marnicio, R.J.

    1988-08-01

    The Environmental Protection Agency's Office of Radiation Programs (ORP) is responsible for regulating on a national level the risks associated with technological sources of ionizing radiation in the environment. A critical activity of the ORP is analyzing and evaluating risk. The ORP believes that the analysis of uncertainty should be an integral part of any risk assessment; therefore, the ORP has initiated a project to develop framework for the treatment of uncertainty in risk analysis. Summaries of recent studies done in five areas of study are presented

  20. The role of uncertainty analysis in dose reconstruction and risk assessment

    International Nuclear Information System (INIS)

    Hoffman, F.O.; Simon, S.L.; Thiessen. K.M.

    1996-01-01

    Dose reconstruction and risk assessment rely heavily on the use of mathematical models to extrapolate information beyond the realm of direct observation. Because models are merely approximations of real systems, their predictions are inherently uncertain. As a result, full disclosure of uncertainty in dose and risk estimates is essential to achieve scientific credibility and to build public trust. The need for formal analysis of uncertainty in model predictions was presented during the nineteenth annual meeting of the NCRP. At that time, quantitative uncertainty analysis was considered a relatively new and difficult subject practiced by only a few investigators. Today, uncertainty analysis has become synonymous with the assessment process itself. When an uncertainty analysis is used iteratively within the assessment process, it can guide experimental research to refine dose and risk estimates, deferring potentially high cost or high consequence decisions until uncertainty is either acceptable or irreducible. Uncertainty analysis is now mandated for all ongoing dose reconstruction projects within the United States, a fact that distinguishes dose reconstruction from other types of exposure and risk assessments. 64 refs., 6 figs., 1 tab

  1. Overview of methods for uncertainty analysis and sensitivity analysis in probabilistic risk assessment

    International Nuclear Information System (INIS)

    Iman, R.L.; Helton, J.C.

    1985-01-01

    Probabilistic Risk Assessment (PRA) is playing an increasingly important role in the nuclear reactor regulatory process. The assessment of uncertainties associated with PRA results is widely recognized as an important part of the analysis process. One of the major criticisms of the Reactor Safety Study was that its representation of uncertainty was inadequate. The desire for the capability to treat uncertainties with the MELCOR risk code being developed at Sandia National Laboratories is indicative of the current interest in this topic. However, as yet, uncertainty analysis and sensitivity analysis in the context of PRA is a relatively immature field. In this paper, available methods for uncertainty analysis and sensitivity analysis in a PRA are reviewed. This review first treats methods for use with individual components of a PRA and then considers how these methods could be combined in the performance of a complete PRA. In the context of this paper, the goal of uncertainty analysis is to measure the imprecision in PRA outcomes of interest, and the goal of sensitivity analysis is to identify the major contributors to this imprecision. There are a number of areas that must be considered in uncertainty analysis and sensitivity analysis for a PRA: (1) information, (2) systems analysis, (3) thermal-hydraulic phenomena/fission product behavior, (4) health and economic consequences, and (5) display of results. Each of these areas and the synthesis of them into a complete PRA are discussed

  2. Including model uncertainty in risk-informed decision making

    International Nuclear Information System (INIS)

    Reinert, Joshua M.; Apostolakis, George E.

    2006-01-01

    Model uncertainties can have a significant impact on decisions regarding licensing basis changes. We present a methodology to identify basic events in the risk assessment that have the potential to change the decision and are known to have significant model uncertainties. Because we work with basic event probabilities, this methodology is not appropriate for analyzing uncertainties that cause a structural change to the model, such as success criteria. We use the risk achievement worth (RAW) importance measure with respect to both the core damage frequency (CDF) and the change in core damage frequency (ΔCDF) to identify potentially important basic events. We cross-check these with generically important model uncertainties. Then, sensitivity analysis is performed on the basic event probabilities, which are used as a proxy for the model parameters, to determine how much error in these probabilities would need to be present in order to impact the decision. A previously submitted licensing basis change is used as a case study. Analysis using the SAPHIRE program identifies 20 basic events as important, four of which have model uncertainties that have been identified in the literature as generally important. The decision is fairly insensitive to uncertainties in these basic events. In three of these cases, one would need to show that model uncertainties would lead to basic event probabilities that would be between two and four orders of magnitude larger than modeled in the risk assessment before they would become important to the decision. More detailed analysis would be required to determine whether these higher probabilities are reasonable. Methods to perform this analysis from the literature are reviewed and an example is demonstrated using the case study

  3. Review of studies related to uncertainty in risk analsis

    Energy Technology Data Exchange (ETDEWEB)

    Rish, W.R.; Marnicio, R.J.

    1988-08-01

    The Environmental Protection Agency's Office of Radiation Programs (ORP) is responsible for regulating on a national level the risks associated with technological sources of ionizing radiation in the environment. A critical activity of the ORP is analyzing and evaluating risk. The ORP believes that the analysis of uncertainty should be an integral part of any risk assessment; therefore, the ORP has initiated a project to develop framework for the treatment of uncertainty in risk analysis. Summaries of recent studies done in five areas of study are presented.

  4. A Quantitative Measure For Evaluating Project Uncertainty Under Variation And Risk Effects

    Directory of Open Access Journals (Sweden)

    A. Chenarani

    2017-10-01

    Full Text Available The effects of uncertainty on a project and the risk event as the consequence of uncertainty are analyzed. The uncertainty index is proposed as a quantitative measure for evaluating the uncertainty of a project. This is done by employing entropy as the indicator of system disorder and lack of information. By employing this index, the uncertainty of each activity and its increase due to risk effects as well as project uncertainty changes as a function of time can be assessed. The results are implemented and analyzed for a small turbojet engine development project as the case study. The results of this study can be useful for project managers and other stakeholders for selecting the most effective risk management and uncertainty controlling method.

  5. Risk Assessment and Decision-Making under Uncertainty in Tunnel and Underground Engineering

    Directory of Open Access Journals (Sweden)

    Yuanpu Xia

    2017-10-01

    Full Text Available The impact of uncertainty on risk assessment and decision-making is increasingly being prioritized, especially for large geotechnical projects such as tunnels, where uncertainty is often the main source of risk. Epistemic uncertainty, which can be reduced, is the focus of attention. In this study, the existing entropy-risk decision model is first discussed and analyzed, and its deficiencies are improved upon and overcome. Then, this study addresses the fact that existing studies only consider parameter uncertainty and ignore the influence of the model uncertainty. Here, focus is on the issue of model uncertainty and differences in risk consciousness with different decision-makers. The utility theory is introduced in the model. Finally, a risk decision model is proposed based on the sensitivity analysis and the tolerance cost, which can improve decision-making efficiency. This research can provide guidance or reference for the evaluation and decision-making of complex systems engineering problems, and indicate a direction for further research of risk assessment and decision-making issues.

  6. Testing Map Features Designed to Convey the Uncertainty of Cancer Risk: Insights Gained From Assessing Judgments of Information Adequacy and Communication Goals.

    Science.gov (United States)

    Severtson, Dolores J

    2015-02-01

    Barriers to communicating the uncertainty of environmental health risks include preferences for certain information and low numeracy. Map features designed to communicate the magnitude and uncertainty of estimated cancer risk from air pollution were tested among 826 participants to assess how map features influenced judgments of adequacy and the intended communication goals. An uncertain versus certain visual feature was judged as less adequate but met both communication goals and addressed numeracy barriers. Expressing relative risk using words communicated uncertainty and addressed numeracy barriers but was judged as highly inadequate. Risk communication and visual cognition concepts were applied to explain findings.

  7. Managing project risks and uncertainties

    Directory of Open Access Journals (Sweden)

    Mike Mentis

    2015-01-01

    Full Text Available This article considers threats to a project slipping on budget, schedule and fit-for-purpose. Threat is used here as the collective for risks (quantifiable bad things that can happen and uncertainties (poorly or not quantifiable bad possible events. Based on experience with projects in developing countries this review considers that (a project slippage is due to uncertainties rather than risks, (b while eventuation of some bad things is beyond control, managed execution and oversight are still the primary means to keeping within budget, on time and fit-for-purpose, (c improving project delivery is less about bigger and more complex and more about coordinated focus, effectiveness and developing thought-out heuristics, and (d projects take longer and cost more partly because threat identification is inaccurate, the scope of identified threats is too narrow, and the threat assessment product is not integrated into overall project decision-making and execution. Almost by definition, what is poorly known is likely to cause problems. Yet it is not just the unquantifiability and intangibility of uncertainties causing project slippage, but that they are insufficiently taken into account in project planning and execution that cause budget and time overruns. Improving project performance requires purpose-driven and managed deployment of scarce seasoned professionals. This can be aided with independent oversight by deeply experienced panelists who contribute technical insights and can potentially show that diligence is seen to be done.

  8. Accounting for predictive uncertainty in a risk analysis focusing on radiological contamination of groundwater

    International Nuclear Information System (INIS)

    Andricevic, R.; Jacobson, R.L.; Daniels, J.I.

    1994-12-01

    This study focuses on the probabilistic travel time approach for predicting transport of radionuclides by groundwater velocity considering parameter uncertainty. The principal entity in the presented model is a travel time probability density function (pdf) conditioned on the set of parameters used to describe different transport processes like advection, dispersion, sorption, and decay. The model is applied to predict the arrival time of radionuclides in groundwater from the Nevada Test Site (NTS) at possible locations of potential human receptors nearby. Because of the lack of sorption the Tritium is found to provide the largest risk. Inclusion of sorption processes indicate that the parameter uncertainty and especially negative correlation between the mean velocity and the sorption strength is instrumental in evaluating the radionuclides arrival time at the prespecified accessible environment. Our analysis of potential health risks takes into consideration uncertainties in physiological attributes, as well as in committed effective dose and the estimate of physical detriment per unit Committed Effective Dose

  9. Accounting for Households' Perceived Income Uncertainty in Consumption Risk Sharing

    NARCIS (Netherlands)

    Singh, S.; Stoltenberg, C.A.

    2017-01-01

    We develop a consumption risk-sharing model that distinguishes households' perceived income uncertainty from income uncertainty as measured by an econometrician. Households receive signals on their future disposable income that can drive a gap between the two uncertainties. Accounting for the

  10. Risk-informed regulation: handling uncertainty for a rational management of safety

    International Nuclear Information System (INIS)

    Zio, Enrico

    2008-01-01

    A risk-informed regulatory approach implies that risk insights be used as supplement of deterministic information for safety decision-making purposes. In this view, the use of risk assessment techniques is expected to lead to improved safety and a more rational allocation of the limited resources available. On the other hand, it is recognized that uncertainties affect both the deterministic safety analyses and the risk assessments. In order for the risk-informed decision making process to be effective, the adequate representation and treatment of such uncertainties is mandatory. In this paper, the risk-informed regulatory framework is considered under the focus of the uncertainty issue. Traditionally, probability theory has provided the language and mathematics for the representation and treatment of uncertainty. More recently, other mathematical structures have been introduced. In particular, the Dempster-Shafer theory of evidence is here illustrated as a generalized framework encompassing probability theory and possibility theory. The special case of probability theory is only addressed as term of comparison, given that it is a well known subject. On the other hand, the special case of possibility theory is amply illustrated. An example of the combination of probability and possibility for treating the uncertainty in the parameters of an event tree is illustrated

  11. Uncertainty propagation in probabilistic risk assessment: A comparative study

    International Nuclear Information System (INIS)

    Ahmed, S.; Metcalf, D.R.; Pegram, J.W.

    1982-01-01

    Three uncertainty propagation techniques, namely method of moments, discrete probability distribution (DPD), and Monte Carlo simulation, generally used in probabilistic risk assessment, are compared and conclusions drawn in terms of the accuracy of the results. For small uncertainty in the basic event unavailabilities, the three methods give similar results. For large uncertainty, the method of moments is in error, and the appropriate method is to propagate uncertainty in the discrete form either by DPD method without sampling or by Monte Carlo. (orig.)

  12. Health significance and statistical uncertainty. The value of P-value.

    Science.gov (United States)

    Consonni, Dario; Bertazzi, Pier Alberto

    2017-10-27

    The P-value is widely used as a summary statistics of scientific results. Unfortunately, there is a widespread tendency to dichotomize its value in "P0.05" ("statistically not significant"), with the former implying a "positive" result and the latter a "negative" one. To show the unsuitability of such an approach when evaluating the effects of environmental and occupational risk factors. We provide examples of distorted use of P-value and of the negative consequences for science and public health of such a black-and-white vision. The rigid interpretation of P-value as a dichotomy favors the confusion between health relevance and statistical significance, discourages thoughtful thinking, and distorts attention from what really matters, the health significance. A much better way to express and communicate scientific results involves reporting effect estimates (e.g., risks, risks ratios or risk differences) and their confidence intervals (CI), which summarize and convey both health significance and statistical uncertainty. Unfortunately, many researchers do not usually consider the whole interval of CI but only examine if it includes the null-value, therefore degrading this procedure to the same P-value dichotomy (statistical significance or not). In reporting statistical results of scientific research present effects estimates with their confidence intervals and do not qualify the P-value as "significant" or "not significant".

  13. Exploiting risk-reward structures in decision making under uncertainty.

    Science.gov (United States)

    Leuker, Christina; Pachur, Thorsten; Hertwig, Ralph; Pleskac, Timothy J

    2018-06-01

    People often have to make decisions under uncertainty-that is, in situations where the probabilities of obtaining a payoff are unknown or at least difficult to ascertain. One solution to this problem is to infer the probability from the magnitude of the potential payoff and thus exploit the inverse relationship between payoffs and probabilities that occurs in many domains in the environment. Here, we investigated how the mind may implement such a solution: (1) Do people learn about risk-reward relationships from the environment-and if so, how? (2) How do learned risk-reward relationships impact preferences in decision-making under uncertainty? Across three experiments (N = 352), we found that participants can learn risk-reward relationships from being exposed to choice environments with a negative, positive, or uncorrelated risk-reward relationship. They were able to learn the associations both from gambles with explicitly stated payoffs and probabilities (Experiments 1 & 2) and from gambles about epistemic events (Experiment 3). In subsequent decisions under uncertainty, participants often exploited the learned association by inferring probabilities from the magnitudes of the payoffs. This inference systematically influenced their preferences under uncertainty: Participants who had been exposed to a negative risk-reward relationship tended to prefer the uncertain option over a smaller sure option for low payoffs, but not for high payoffs. This pattern reversed in the positive condition and disappeared in the uncorrelated condition. This adaptive change in preferences is consistent with the use of the risk-reward heuristic. Copyright © 2018 Elsevier B.V. All rights reserved.

  14. The spectre of uncertainty in communicating technological risk

    Energy Technology Data Exchange (ETDEWEB)

    Broesius, Michael T. [Univ. of California, Livermore, CA (United States)

    1993-12-01

    The literature does not clearly describe the potential moral and ethical conflicts that can exist between technology sponsors and the technical communicators whose job it is to present potentially risky technology to the non-technical people most likely to be imperiled by such risk. Equally important, the literature does not address the issue of uncertainty -- not the uncertainty likely to be experienced by the community at risk, but the unreliable processes and methodologies used by technology sponsors to define, quantify, and develop strategies to mitigate technological risks. In this paper, the author goes beyond a description of risk communication, the nature of the generally predictable interaction between technology advocates and non-technically trained individuals, and current trends in the field. Although that kind of information is critical to the success of any risk communication activity, and he has included it when necessary to provide background and perspective, without knowing how and why risk assessment is done, it has limited practical applicability outside the sterile, value-free vacuum in which it is usually framed. Technical communicators, particularly those responsible for communicating potential technological risk, must also understand the social, political, economic, statistical, and ethical issues they will invariably encounter.

  15. Uncertainty Instability Risk Analysis of High Concrete Arch Dam Abutments

    Directory of Open Access Journals (Sweden)

    Xin Cao

    2017-01-01

    Full Text Available The uncertainties associated with concrete arch dams rise with the increased height of dams. Given the uncertainties associated with influencing factors, the stability of high arch dam abutments as a fuzzy random event was studied. In addition, given the randomness and fuzziness of calculation parameters as well as the failure criterion, hazard point and hazard surface uncertainty instability risk ratio models were proposed for high arch dam abutments on the basis of credibility theory. The uncertainty instability failure criterion was derived through the analysis of the progressive instability failure process on the basis of Shannon’s entropy theory. The uncertainties associated with influencing factors were quantized by probability or possibility distribution assignments. Gaussian random theory was used to generate random realizations for influence factors with spatial variability. The uncertainty stability analysis method was proposed by combining the finite element analysis and the limit equilibrium method. The instability risk ratio was calculated using the Monte Carlo simulation method and fuzzy random postprocessing. Results corroborate that the modeling approach is sound and that the calculation method is feasible.

  16. Risk analysis under uncertainty, the precautionary principle, and the new EU chemicals strategy.

    Science.gov (United States)

    Rogers, Michael D

    2003-06-01

    Three categories of uncertainty in relation to risk assessment are defined; uncertainty in effect, uncertainty in cause, and uncertainty in the relationship between a hypothesised cause and effect. The Precautionary Principle (PP) relates to the third type of uncertainty. Three broad descriptions of the PP are set out, uncertainty justifies action, uncertainty requires action, and uncertainty requires a reversal of the burden of proof for risk assessments. The application of the PP is controversial but what matters in practise is the precautionary action (PA) that follows. The criteria by which the PAs should be judged are detailed. This framework for risk assessment and management under uncertainty is then applied to the envisaged European system for the regulation of chemicals. A new EU regulatory system has been proposed which shifts the burden of proof concerning risk assessments from the regulator to the producer, and embodies the PP in all three of its main regulatory stages. The proposals are critically discussed in relation to three chemicals, namely, atrazine (an endocrine disrupter), cadmium (toxic and possibly carcinogenic), and hydrogen fluoride (a toxic, high-production-volume chemical). Reversing the burden of proof will speed up the regulatory process but the examples demonstrate that applying the PP appropriately, and balancing the countervailing risks and the socio-economic benefits, will continue to be a difficult task for the regulator. The paper concludes with a discussion of the role of precaution in the management of change and of the importance of trust in the effective regulation of uncertain risks.

  17. Dealing with uncertainty arising out of probabilistic risk assessment

    International Nuclear Information System (INIS)

    Solomon, K.A.; Kastenberg, W.E.; Nelson, P.F.

    1984-03-01

    In addressing the area of safety goal implementation, the question of uncertainty arises. This report suggests that the Nuclear Regulatory Commission (NRC) should examine how other regulatory organizations have addressed the issue. Several examples are given from the chemical industry, and comparisons are made to nuclear power risks. Recommendations are made as to various considerations that the NRC should require in probabilistic risk assessments in order to properly treat uncertainties in the implementation of the safety goal policy. 40 references, 7 figures, 5 tables

  18. Real-Time Optimal Flood Control Decision Making and Risk Propagation Under Multiple Uncertainties

    Science.gov (United States)

    Zhu, Feilin; Zhong, Ping-An; Sun, Yimeng; Yeh, William W.-G.

    2017-12-01

    Multiple uncertainties exist in the optimal flood control decision-making process, presenting risks involving flood control decisions. This paper defines the main steps in optimal flood control decision making that constitute the Forecast-Optimization-Decision Making (FODM) chain. We propose a framework for supporting optimal flood control decision making under multiple uncertainties and evaluate risk propagation along the FODM chain from a holistic perspective. To deal with uncertainties, we employ stochastic models at each link of the FODM chain. We generate synthetic ensemble flood forecasts via the martingale model of forecast evolution. We then establish a multiobjective stochastic programming with recourse model for optimal flood control operation. The Pareto front under uncertainty is derived via the constraint method coupled with a two-step process. We propose a novel SMAA-TOPSIS model for stochastic multicriteria decision making. Then we propose the risk assessment model, the risk of decision-making errors and rank uncertainty degree to quantify the risk propagation process along the FODM chain. We conduct numerical experiments to investigate the effects of flood forecast uncertainty on optimal flood control decision making and risk propagation. We apply the proposed methodology to a flood control system in the Daduhe River basin in China. The results indicate that the proposed method can provide valuable risk information in each link of the FODM chain and enable risk-informed decisions with higher reliability.

  19. Uncertainty and risk in wildland fire management: A review

    Science.gov (United States)

    Matthew P. Thompson; Dave E. Calkin

    2011-01-01

    Wildland fire management is subject to manifold sources of uncertainty. Beyond the unpredictability of wildfire behavior, uncertainty stems from inaccurate/missing data, limited resource value measures to guide prioritization across fires and resources at risk, and an incomplete scientific understanding of ecological response to fire, of fire behavior response to...

  20. Quantile uncertainty and value-at-risk model risk.

    Science.gov (United States)

    Alexander, Carol; Sarabia, José María

    2012-08-01

    This article develops a methodology for quantifying model risk in quantile risk estimates. The application of quantile estimates to risk assessment has become common practice in many disciplines, including hydrology, climate change, statistical process control, insurance and actuarial science, and the uncertainty surrounding these estimates has long been recognized. Our work is particularly important in finance, where quantile estimates (called Value-at-Risk) have been the cornerstone of banking risk management since the mid 1980s. A recent amendment to the Basel II Accord recommends additional market risk capital to cover all sources of "model risk" in the estimation of these quantiles. We provide a novel and elegant framework whereby quantile estimates are adjusted for model risk, relative to a benchmark which represents the state of knowledge of the authority that is responsible for model risk. A simulation experiment in which the degree of model risk is controlled illustrates how to quantify Value-at-Risk model risk and compute the required regulatory capital add-on for banks. An empirical example based on real data shows how the methodology can be put into practice, using only two time series (daily Value-at-Risk and daily profit and loss) from a large bank. We conclude with a discussion of potential applications to nonfinancial risks. © 2012 Society for Risk Analysis.

  1. Low-dose extrapolation of radiation health risks: some implications of uncertainty for radiation protection at low doses.

    Science.gov (United States)

    Land, Charles E

    2009-11-01

    Ionizing radiation is a known and well-quantified human cancer risk factor, based on a remarkably consistent body of information from epidemiological studies of exposed populations. Typical examples of risk estimation include use of Japanese atomic bomb survivor data to estimate future risk from radiation-related cancer among American patients receiving multiple computed tomography scans, persons affected by radioactive fallout, or persons whose livelihoods involve some radiation exposure, such as x-ray technicians, interventional radiologists, or shipyard workers. Our estimates of radiation-related risk are uncertain, reflecting statistical variation and our imperfect understanding of crucial assumptions that must be made if we are to apply existing epidemiological data to particular situations. Fortunately, that uncertainty is also highly quantifiable, and can be presented concisely and transparently. Radiation protection is ultimately a political process that involves consent by stakeholders, a diverse group that includes people who might be expected to be risk-averse and concerned with plausible upper limits on risk (how bad could it be?), cost-averse and concerned with lower limits on risk (can you prove there is a nontrivial risk at current dose levels?), or combining both points of view. How radiation-related risk is viewed by individuals and population subgroups also depends very much on perception of related benefit, which might be (for example) medical, economic, altruistic, or nonexistent. The following presentation follows the lead of National Council on Radiation Protection and Measurements (NCRP) Commentary 14, NCRP Report 126, and later documents in treating radiation protection from the viewpoint of quantitative uncertainty analysis.

  2. Uncertainty and sensitivity analysis of environmental and health risks of nanomaterials

    DEFF Research Database (Denmark)

    Grieger, Khara Deanne; Hansen, Steffen Foss; Baun, Anders

    Scientific uncertainty about the environmental, health and safety issues (EHS) of nanomaterials has been recognized by scientists, regulators, NGO’s as well as industry as a possible barrier towards nanotechnology reaching its full potential. Historically, research efforts tend to be directed...... within EHS knowledge and research for the sake of science itself, it is also crucial that these research efforts are strategically focused and prioritized in order to assist regulators, industry, as well as scientists in the EHS challenges that face them in developing nanomaterials. Therefore, this study...... characterisation of engineered nanoparticles according to several reports. This includes establishing, developing and standardising reference materials, monitoring and detection equipment and estimating human and environmental exposure concentrations. These issues ultimately lead to significant challenges...

  3. Construction of a case for expert judgement of uncertainty in early health effects models

    International Nuclear Information System (INIS)

    Grupa, J.

    1997-11-01

    The contribution of ECN to a joint study of the European Commission (EC) and the US Nuclear Regulatory Commission (NRC), in which the uncertainty in risks and consequences of severe accidents at nuclear power plants are evaluated, is described. The procedure used to obtain these uncertainties is called expert judgement. In a formal expert judgement procedure a panel of experts has provided quantitative information about the uncertainty in given observables: a quantity that describes an observation concerning the phenomenon of interest, in this paper the relation between dose and health effects, without information or assumptions about any model describing this phenomenon. The observables are defined in a case structure, a questionnaire provided to all experts. ECN has contributed to the selection of the experts for the early health effects panel, and provided assistance for drafting the case structure for this panel. This paper describes the radiological information provided by ECN and the analyses necessary for constructing the case structure. The deliverables of the expert elicitation are uncertainty distributions of the observables requested in the case structure. The results are intended to be unbiased, i.e. it should be applicable to any model describing the relation between dose and health effects. They will be published by the project team in a joint publication of the NRC and the EC. In this way the resulting uncertainty distributions are available for further work in the joint project and available to a more general public. 2 figs., 4 refs

  4. A review of different perspectives on uncertainty and risk and an alternative modeling paradigm

    International Nuclear Information System (INIS)

    Samson, Sundeep; Reneke, James A.; Wiecek, Margaret M.

    2009-01-01

    The literature in economics, finance, operations research, engineering and in general mathematics is first reviewed on the subject of defining uncertainty and risk. The review goes back to 1901. Different perspectives on uncertainty and risk are examined and a new paradigm to model uncertainty and risk is proposed using relevant ideas from this study. This new paradigm is used to represent, aggregate and propagate uncertainty and interpret the resulting variability in a challenge problem developed by Oberkampf et al. [2004, Challenge problems: uncertainty in system response given uncertain parameters. Reliab Eng Syst Safety 2004; 85(1): 11-9]. The challenge problem is further extended into a decision problem that is treated within a multicriteria decision making framework to illustrate how the new paradigm yields optimal decisions under uncertainty. The accompanying risk is defined as the probability of an unsatisfactory system response quantified by a random function of the uncertainty

  5. Uncertainty in exposure of underground miners to radon daughters and the effect of uncertainty on risk estimates

    International Nuclear Information System (INIS)

    1989-10-01

    Studies of underground miners provide the principal basis for assessing the risk from radon daughter exposure. An important problem in all epidemiological studies of underground miners is the reliability of the estimates of the miners' exposures. This study examines the various sources of uncertainty in exposure estimation for the principal epidemiologic studies reported in the literature including the temporal and spatial variability of radon sources and, with the passage of time, changes to both mining methods and ventilation conditions. Uncertainties about work histories and the role of other hard rock mining experience are also discussed. The report also describes two statistical approaches, both based on Bayesian methods, by which the effects on the estimated risk coefficient of uncertainty in exposure (WLM) can be examined. One approach requires only an estimate of the cumulative WLM exposure of a group of miners, an estimate of the number of (excess) lung cancers potentially attributable to that exposure, and a specification of the uncertainty about the cumulative exposure of the group. The second approach is based on a linear regression model which incorporates errors (uncertainty) in the independent variable (WLM) and allows the dependent variable (cases) to be Poisson distributed. The method permits the calculation of marginal probability distributions for either slope (risk coefficient) or intercept. The regression model approach is applied to several published data sets from epidemiological studies of miners. Specific results are provided for each data set and apparent differences in risk coefficients are discussed. The studies of U.S. uranium miners, Ontario uranium miners and Czechoslovakian uranium miners are argued to provide the best basis for risk estimation at this time. In general terms, none of the analyses performed are inconsistent with a linear exposure-effect relation. Based on analyses of the overall miner groups, the most likely ranges

  6. Uncertainty estimation and risk prediction in air quality

    International Nuclear Information System (INIS)

    Garaud, Damien

    2011-01-01

    This work is about uncertainty estimation and risk prediction in air quality. Firstly, we build a multi-model ensemble of air quality simulations which can take into account all uncertainty sources related to air quality modeling. Ensembles of photochemical simulations at continental and regional scales are automatically generated. Then, these ensemble are calibrated with a combinatorial optimization method. It selects a sub-ensemble which is representative of uncertainty or shows good resolution and reliability for probabilistic forecasting. This work shows that it is possible to estimate and forecast uncertainty fields related to ozone and nitrogen dioxide concentrations or to improve the reliability of threshold exceedance predictions. The approach is compared with Monte Carlo simulations, calibrated or not. The Monte Carlo approach appears to be less representative of the uncertainties than the multi-model approach. Finally, we quantify the observational error, the representativeness error and the modeling errors. The work is applied to the impact of thermal power plants, in order to quantify the uncertainty on the impact estimates. (author) [fr

  7. The treatment of uncertainties in risk for regulatory decision making

    International Nuclear Information System (INIS)

    Baybutt, P.; Cox, D.C.; Denning, R.S.; Kurth, R.E.; Fraley, D.W.; Heaberlin, S.W.

    1982-01-01

    This paper describes research conducted in an ongoing program at Battelle to develop and adapt decision analysis methods for regulatory decision making. A general approach to risk-based decision making is discussed. The nature of uncertainties in risk assessment is described and methods for their inclusion in decision making are proposed. The use of decision analysis methods in regulatory decision making and the consideration of uncertainties is illustrated in a realistic case study

  8. Managing uncertainty: a grounded theory of stigma in transgender health care encounters.

    Science.gov (United States)

    Poteat, Tonia; German, Danielle; Kerrigan, Deanna

    2013-05-01

    A growing body of literature supports stigma and discrimination as fundamental causes of health disparities. Stigma and discrimination experienced by transgender people have been associated with increased risk for depression, suicide, and HIV. Transgender stigma and discrimination experienced in health care influence transgender people's health care access and utilization. Thus, understanding how stigma and discrimination manifest and function in health care encounters is critical to addressing health disparities for transgender people. A qualitative, grounded theory approach was taken to this study of stigma in health care interactions. Between January and July 2011, fifty-five transgender people and twelve medical providers participated in one-time in-depth interviews about stigma, discrimination, and health care interactions between providers and transgender patients. Due to the social and institutional stigma against transgender people, their care is excluded from medical training. Therefore, providers approach medical encounters with transgender patients with ambivalence and uncertainty. Transgender people anticipate that providers will not know how to meet their needs. This uncertainty and ambivalence in the medical encounter upsets the normal balance of power in provider-patient relationships. Interpersonal stigma functions to reinforce the power and authority of the medical provider during these interactions. Functional theories of stigma posit that we hold stigmatizing attitudes because they serve specific psychological functions. However, these theories ignore how hierarchies of power in social relationships serve to maintain and reinforce inequalities. The findings of this study suggest that interpersonal stigma also functions to reinforce medical power and authority in the face of provider uncertainty. Within functional theories of stigma, it is important to acknowledge the role of power and to understand how stigmatizing attitudes function to maintain

  9. Probabilistic human health risk assessment of degradation-related chemical mixtures in heterogeneous aquifers: Risk statistics, hot spots, and preferential channels

    Science.gov (United States)

    Henri, Christopher V.; Fernàndez-Garcia, Daniel; de Barros, Felipe P. J.

    2015-06-01

    The increasing presence of toxic chemicals released in the subsurface has led to a rapid growth of social concerns and the need to develop and employ models that can predict the impact of groundwater contamination on human health risk under uncertainty. Monitored natural attenuation is a common remediation action in many contamination cases. However, natural attenuation can lead to the production of daughter species of distinct toxicity that may pose challenges in pollution management strategies. The actual threat that these contaminants pose to human health depends on the interplay between the complex structure of the geological media and the toxicity of each pollutant byproduct. This work addresses human health risk for chemical mixtures resulting from the sequential degradation of a contaminant (such as a chlorinated solvent) under uncertainty through high-resolution three-dimensional numerical simulations. We systematically investigate the interaction between aquifer heterogeneity, flow connectivity, contaminant injection model, and chemical toxicity in the probabilistic characterization of health risk. We illustrate how chemical-specific travel times control the regime of the expected risk and its corresponding uncertainties. Results indicate conditions where preferential flow paths can favor the reduction of the overall risk of the chemical mixture. The overall human risk response to aquifer connectivity is shown to be nontrivial for multispecies transport. This nontriviality is a result of the interaction between aquifer heterogeneity and chemical toxicity. To quantify the joint effect of connectivity and toxicity in health risk, we propose a toxicity-based Damköhler number. Furthermore, we provide a statistical characterization in terms of low-order moments and the probability density function of the individual and total risks.

  10. RISK CORRIDORS AND REINSURANCE IN HEALTH INSURANCE MARKETPLACES: Insurance for Insurers

    OpenAIRE

    LAYTON, TIMOTHY J.; MCGUIRE, THOMAS G.; SINAIKO, ANNA D.

    2016-01-01

    In order to encourage entry and lower prices, most regulated markets for health insurance include policies that seek to reduce the uncertainty faced by insurers. In addition to risk adjustment of premiums paid to plans, the Health Insurance Marketplaces established by the Affordable Care Act implement reinsurance and risk corridors. Reinsurance limits insurer costs associated with specific individuals, while risk corridors protect against aggregate losses. Both tighten the insurer's distribut...

  11. Risk Management and Uncertainty in Large Complex Public Projects

    DEFF Research Database (Denmark)

    Neerup Themsen, Tim; Harty, Chris; Tryggestad, Kjell

    Governmental actors worldwide are promoting risk management as a rational approach to man-age uncertainty and improve the abilities to deliver large complex projects according to budget, time plans, and pre-set project specifications: But what do we know about the effects of risk management...... on the abilities to meet such objectives? Using Callon’s (1998) twin notions of framing and overflowing we examine the implementation of risk management within the Dan-ish public sector and the effects this generated for the management of two large complex pro-jects. We show how the rational framing of risk...... management have generated unexpected costly outcomes such as: the undermining of the longer-term value and societal relevance of the built asset, the negligence of the wider range of uncertainties emerging during project processes, and constraining forms of knowledge. We also show how expert accountants play...

  12. Modelling and propagation of uncertainties in the German Risk Study

    International Nuclear Information System (INIS)

    Hofer, E.; Krzykacz, B.

    1982-01-01

    Risk assessments are generally subject to uncertainty considerations. This is because of the various estimates that are involved. The paper points out those estimates in the so-called phase A of the German Risk Study, for which uncertainties were quantified. It explains the probabilistic models applied in the assessment to their impact on the findings of the study. Finally the resulting subjective confidence intervals of the study results are presented and their sensitivity to these probabilistic models is investigated

  13. What risk assessments of genetically modified organisms can learn from institutional analyses of public health risks.

    Science.gov (United States)

    Rajan, S Ravi; Letourneau, Deborah K

    2012-01-01

    The risks of genetically modified organisms (GMOs) are evaluated traditionally by combining hazard identification and exposure estimates to provide decision support for regulatory agencies. We question the utility of the classical risk paradigm and discuss its evolution in GMO risk assessment. First, we consider the problem of uncertainty, by comparing risk assessment for environmental toxins in the public health domain with genetically modified organisms in the environment; we use the specific comparison of an insecticide to a transgenic, insecticidal food crop. Next, we examine normal accident theory (NAT) as a heuristic to consider runaway effects of GMOs, such as negative community level consequences of gene flow from transgenic, insecticidal crops. These examples illustrate how risk assessments are made more complex and contentious by both their inherent uncertainty and the inevitability of failure beyond expectation in complex systems. We emphasize the value of conducting decision-support research, embracing uncertainty, increasing transparency, and building interdisciplinary institutions that can address the complex interactions between ecosystems and society. In particular, we argue against black boxing risk analysis, and for a program to educate policy makers about uncertainty and complexity, so that eventually, decision making is not the burden that falls upon scientists but is assumed by the public at large.

  14. What Risk Assessments of Genetically Modified Organisms Can Learn from Institutional Analyses of Public Health Risks

    Directory of Open Access Journals (Sweden)

    S. Ravi Rajan

    2012-01-01

    Full Text Available The risks of genetically modified organisms (GMOs are evaluated traditionally by combining hazard identification and exposure estimates to provide decision support for regulatory agencies. We question the utility of the classical risk paradigm and discuss its evolution in GMO risk assessment. First, we consider the problem of uncertainty, by comparing risk assessment for environmental toxins in the public health domain with genetically modified organisms in the environment; we use the specific comparison of an insecticide to a transgenic, insecticidal food crop. Next, we examine normal accident theory (NAT as a heuristic to consider runaway effects of GMOs, such as negative community level consequences of gene flow from transgenic, insecticidal crops. These examples illustrate how risk assessments are made more complex and contentious by both their inherent uncertainty and the inevitability of failure beyond expectation in complex systems. We emphasize the value of conducting decision-support research, embracing uncertainty, increasing transparency, and building interdisciplinary institutions that can address the complex interactions between ecosystems and society. In particular, we argue against black boxing risk analysis, and for a program to educate policy makers about uncertainty and complexity, so that eventually, decision making is not the burden that falls upon scientists but is assumed by the public at large.

  15. Health risk assessment of exposure to ionizing radiation

    International Nuclear Information System (INIS)

    Ogata, Hiromitsu

    2011-01-01

    Risk assessment is an essential process for evaluating the human health effects of exposure to ionizing radiation and for determining acceptable levels of exposure. There are two major components of radiation risk assessment: a measure of exposure level and a measure of disease occurrence. For quantitative estimation of health risks, it is important to evaluate the association between exposure and disease occurrence using epidemiological or experimental data. In these approaches, statistical risk models are used particularly for estimating cancer risks related to exposure to low levels of radiation. This paper presents a summary of basic models and methods of risk assessment for studying exposure-risk relationships. Moreover, quantitative risk estimates are subject to several sources of uncertainty due to inherent limitations in risk assessment studies. This paper also discusses the limitations of radiation risk assessment. (author)

  16. Operational Implementation of a Pc Uncertainty Construct for Conjunction Assessment Risk Analysis

    Science.gov (United States)

    Newman, Lauri K.; Hejduk, Matthew D.; Johnson, Lauren C.

    2016-01-01

    Earlier this year the NASA Conjunction Assessment and Risk Analysis (CARA) project presented the theoretical and algorithmic aspects of a method to include the uncertainties in the calculation inputs when computing the probability of collision (Pc) between two space objects, principally uncertainties in the covariances and the hard-body radius. The output of this calculation approach is to produce rather than a single Pc value an entire probability density function that will represent the range of possible Pc values given the uncertainties in the inputs and bring CA risk analysis methodologies more in line with modern risk management theory. The present study provides results from the exercise of this method against an extended dataset of satellite conjunctions in order to determine the effect of its use on the evaluation of conjunction assessment (CA) event risk posture. The effects are found to be considerable: a good number of events are downgraded from or upgraded to a serious risk designation on the basis of consideration of the Pc uncertainty. The findings counsel the integration of the developed methods into NASA CA operations.

  17. Risk Analysis of Reservoir Flood Routing Calculation Based on Inflow Forecast Uncertainty

    Directory of Open Access Journals (Sweden)

    Binquan Li

    2016-10-01

    Full Text Available Possible risks in reservoir flood control and regulation cannot be objectively assessed by deterministic flood forecasts, resulting in the probability of reservoir failure. We demonstrated a risk analysis of reservoir flood routing calculation accounting for inflow forecast uncertainty in a sub-basin of Huaihe River, China. The Xinanjiang model was used to provide deterministic flood forecasts, and was combined with the Hydrologic Uncertainty Processor (HUP to quantify reservoir inflow uncertainty in the probability density function (PDF form. Furthermore, the PDFs of reservoir water level (RWL and the risk rate of RWL exceeding a defined safety control level could be obtained. Results suggested that the median forecast (50th percentiles of HUP showed better agreement with observed inflows than the Xinanjiang model did in terms of the performance measures of flood process, peak, and volume. In addition, most observations (77.2% were bracketed by the uncertainty band of 90% confidence interval, with some small exceptions of high flows. Results proved that this framework of risk analysis could provide not only the deterministic forecasts of inflow and RWL, but also the fundamental uncertainty information (e.g., 90% confidence band for the reservoir flood routing calculation.

  18. Evaluating Sources of Risks in Large Engineering Projects: The Roles of Equivocality and Uncertainty

    Directory of Open Access Journals (Sweden)

    Leena Pekkinen

    2015-11-01

    Full Text Available Contemporary project risk management literature introduces uncertainty, i.e., the lack of information, as a fundamental basis of project risks. In this study the authors assert that equivocality, i.e., the existence of multiple and conflicting interpretations, can also serve as a basis of risks. With an in-depth empirical investigation of a large complex engineering project the authors identified risk sources having their bases in the situations where uncertainty or equivocality was the predominant attribute. The information processing theory proposes different managerial practices for risk management based on the sources of risks in uncertainty or equivocality.

  19. Quantification of uncertainty in flood risk assessment for flood protection planning: a Bayesian approach

    Science.gov (United States)

    Dittes, Beatrice; Špačková, Olga; Ebrahimian, Negin; Kaiser, Maria; Rieger, Wolfgang; Disse, Markus; Straub, Daniel

    2017-04-01

    Flood risk estimates are subject to significant uncertainties, e.g. due to limited records of historic flood events, uncertainty in flood modeling, uncertain impact of climate change or uncertainty in the exposure and loss estimates. In traditional design of flood protection systems, these uncertainties are typically just accounted for implicitly, based on engineering judgment. In the AdaptRisk project, we develop a fully quantitative framework for planning of flood protection systems under current and future uncertainties using quantitative pre-posterior Bayesian decision analysis. In this contribution, we focus on the quantification of the uncertainties and study their relative influence on the flood risk estimate and on the planning of flood protection systems. The following uncertainty components are included using a Bayesian approach: 1) inherent and statistical (i.e. limited record length) uncertainty; 2) climate uncertainty that can be learned from an ensemble of GCM-RCM models; 3) estimates of climate uncertainty components not covered in 2), such as bias correction, incomplete ensemble, local specifics not captured by the GCM-RCM models; 4) uncertainty in the inundation modelling; 5) uncertainty in damage estimation. We also investigate how these uncertainties are possibly reduced in the future when new evidence - such as new climate models, observed extreme events, and socio-economic data - becomes available. Finally, we look into how this new evidence influences the risk assessment and effectivity of flood protection systems. We demonstrate our methodology for a pre-alpine catchment in southern Germany: the Mangfall catchment in Bavaria that includes the city of Rosenheim, which suffered significant losses during the 2013 flood event.

  20. A risk assessment methodology for incorporating uncertainties using fuzzy concepts

    International Nuclear Information System (INIS)

    Cho, Hyo-Nam; Choi, Hyun-Ho; Kim, Yoon-Bae

    2002-01-01

    This paper proposes a new methodology for incorporating uncertainties using fuzzy concepts into conventional risk assessment frameworks. This paper also introduces new forms of fuzzy membership curves, designed to consider the uncertainty range that represents the degree of uncertainties involved in both probabilistic parameter estimates and subjective judgments, since it is often difficult or even impossible to precisely estimate the occurrence rate of an event in terms of one single crisp probability. It is to be noted that simple linguistic variables such as 'High/Low' and 'Good/Bad' have the limitations in quantifying the various risks inherent in construction projects, but only represent subjective mental cognition adequately. Therefore, in this paper, the statements that include some quantification with giving specific value or scale, such as 'Close to any value' or 'Higher/Lower than analyzed value', are used in order to get over the limitations. It may be stated that the proposed methodology will be very useful for the systematic and rational risk assessment of construction projects

  1. Recent developments in health risks modeling techniques applied to hazardous waste site assessment and remediation

    International Nuclear Information System (INIS)

    Mendez, W.M. Jr.

    1990-01-01

    Remediation of hazardous an mixed waste sites is often driven by assessments of human health risks posed by the exposures to hazardous substances released from these sites. The methods used to assess potential health risk involve, either implicitly or explicitly, models for pollutant releases, transport, human exposure and intake, and for characterizing health effects. Because knowledge about pollutant fate transport processes at most waste sites is quite limited, and data cost are quite high, most of the models currently used to assess risk, and endorsed by regulatory agencies, are quite simple. The models employ many simplifying assumptions about pollutant fate and distribution in the environment about human pollutant intake, and toxicologic responses to pollutant exposures. An important consequence of data scarcity and model simplification is that risk estimates are quite uncertain and estimates of the magnitude uncertainty associated with risk assessment has been very difficult. A number of methods have been developed to address the issue of uncertainty in risk assessments in a manner that realistically reflects uncertainty in model specification and data limitations. These methods include definition of multiple exposure scenarios, sensitivity analyses, and explicit probabilistic modeling of uncertainty. Recent developments in this area will be discussed, along with their possible impacts on remediation programs, and remaining obstacles to their wider use and acceptance by the scientific and regulatory communities

  2. Environmental impact and risk assessments and key factors contributing to the overall uncertainties

    International Nuclear Information System (INIS)

    Salbu, Brit

    2016-01-01

    There is a significant number of nuclear and radiological sources that have contributed, are still contributing, or have the potential to contribute to radioactive contamination of the environment in the future. To protect the environment from radioactive contamination, impact and risk assessments are performed prior to or during a release event, short or long term after deposition or prior and after implementation of countermeasures. When environmental impact and risks are assessed, however, a series of factors will contribute to the overall uncertainties. To provide environmental impact and risk assessments, information on processes, kinetics and a series of input variables is needed. Adding problems such as variability, questionable assumptions, gaps in knowledge, extrapolations and poor conceptual model structures, a series of factors are contributing to large and often unacceptable uncertainties in impact and risk assessments. Information on the source term and the release scenario is an essential starting point in impact and risk models; the source determines activity concentrations and atom ratios of radionuclides released, while the release scenario determine the physico-chemical forms of released radionuclides such as particle size distribution, structure and density. Releases will most often contain other contaminants such as metals, and due to interactions, contaminated sites should be assessed as a multiple stressor scenario. Following deposition, a series of stressors, interactions and processes will influence the ecosystem transfer of radionuclide species and thereby influence biological uptake (toxicokinetics) and responses (toxicodynamics) in exposed organisms. Due to the variety of biological species, extrapolation is frequently needed to fill gaps in knowledge e.g., from effects to no effects, from effects in one organism to others, from one stressor to mixtures. Most toxtests are, however, performed as short term exposure of adult organisms

  3. Risk in technical and scientific studies: general introduction to uncertainty management and the concept of risk

    International Nuclear Information System (INIS)

    Apostolakis, G.E.

    2004-01-01

    George Apostolakis (MIT) presented an introduction to the concept of risk and uncertainty management and their use in technical and scientific studies. He noted that Quantitative Risk Assessment (QRA) provides support to the overall treatment of a system as an integrated socio-technical system. Specifically, QRA aims to answer the questions: - What can go wrong (e.g., accident sequences or scenarios)? - How likely are these sequences or scenarios? - What are the consequences of these sequences or scenarios? The Quantitative Risk Assessment deals with two major types of uncertainty. An assessment requires a 'model of the world', and this preferably would be a deterministic model based on underlying processes. In practice, there are uncertainties in this model of the world relating to variability or randomness that cannot be accounted for directly in a deterministic model and that may require a probabilistic or aleatory model. Both deterministic and aleatory models of the world have assumptions and parameters, and there are 'state-of-knowledge' or epistemic uncertainties associated with these. Sensitivity studies or eliciting expert opinion can be used to address the uncertainties in assumptions, and the level of confidence in parameter values can be characterised using probability distributions (pdfs). Overall, the distinction between aleatory and epistemic uncertainties is not always clear, and both can be treated mathematically in the same way. Lessons on safety assessments that can be learnt from experience at nuclear power plants are that beliefs about what is important can be wrong if a risk assessment is not performed. Also, precautionary approaches are not always conservative if failure modes are not identified. Nevertheless, it is important to recognize that uncertainties will remain despite a quantitative risk assessment: e.g., is the scenario list complete, are the models accepted as reasonable, and are parameter probability distributions representative of

  4. Sensing risk, fearing uncertainty: Systems science approach to change.

    Directory of Open Access Journals (Sweden)

    Ivo P Janecka

    2014-03-01

    Full Text Available BackgroundMedicine devotes its primary focus to understanding change, from cells to network relationships; observations of non-linearity are inescapable. Recent events provide extraordinary examples of major non-linear surprises within the societal system: human genome-from anticipated 100,000+ genes to only 20,000+; junk DNA-initially ignored but now proven to control genetic processes; economic reversals-bursting of bubbles in technology, housing, finance; foreign wars; relentless rise in obesity, neurodegenerative diseases.There are two attributes of systems science that are especially relevant to this research: One- it offers a method for creating a structural context with a guiding path to pragmatic knowledge; and, two- it gives pre-eminence to sensory input capable to register, evaluate, and react to change. Material / MethodPublic domain records of change, during the last fifty years, have been studied in the context of systems science, the dynamic systems model, and various cycles. Results / Conclusions Change is dynamic, ever-present, never isolated, and of variable impact; it reflects innumerable relationships among contextual systems; change can be perceived as risk or uncertainty depending upon how the assessment is made; risk is quantifiable by sensory input and generates a degree of rational optimism; uncertainty is not quantifiable and evokes fear; trust is key to sharing risk; the measurable financial credit can be a proxy for societal trust; expanding credit dilutes trust; when a credit bubble bursts, so will trust; absence of trust paralyzes systems’ relationships leading to disorganized complexity which prevents value creation and heightens the probability of random events; disappearance of value, accompanied by chaos, threatens all systems.From personal health to economic sustainability and collective rationality, most examined components of the societal system were found not to be optimized and trust was not in evidence.

  5. Probabilistic accident consequence uncertainty analysis -- Early health effects uncertainty assessment. Volume 2: Appendices

    Energy Technology Data Exchange (ETDEWEB)

    Haskin, F.E. [Univ. of New Mexico, Albuquerque, NM (United States); Harper, F.T. [Sandia National Labs., Albuquerque, NM (United States); Goossens, L.H.J.; Kraan, B.C.P. [Delft Univ. of Technology (Netherlands)

    1997-12-01

    The development of two new probabilistic accident consequence codes, MACCS and COSYMA, was completed in 1990. These codes estimate the consequence from the accidental releases of radiological material from hypothesized accidents at nuclear installations. In 1991, the US Nuclear Regulatory Commission and the Commission of the European Communities began cosponsoring a joint uncertainty analysis of the two codes. The ultimate objective of this joint effort was to systematically develop credible and traceable uncertainty distributions for the respective code input variables. A formal expert judgment elicitation and evaluation process was identified as the best technology available for developing a library of uncertainty distributions for these consequence parameters. This report focuses on the results of the study to develop distribution for variables related to the MACCS and COSYMA early health effects models. This volume contains appendices that include (1) a summary of the MACCS and COSYMA consequence codes, (2) the elicitation questionnaires and case structures, (3) the rationales and results for the panel on early health effects, (4) short biographies of the experts, and (5) the aggregated results of their responses.

  6. The characterisation and evaluation of uncertainty in probabilistic risk analysis

    International Nuclear Information System (INIS)

    Parry, G.W.; Winter, P.W.

    1980-10-01

    The sources of uncertainty in probabilistic risk analysis are discussed using the event/fault tree methodology as an example. The role of statistics in quantifying these uncertainties is investigated. A class of uncertainties is identified which is, at present, unquantifiable, using either classical or Bayesian statistics. It is argued that Bayesian statistics is the more appropriate vehicle for the probabilistic analysis of rare events and a short review is given with some discussion on the representation of ignorance. (author)

  7. Sensitivity to Uncertainty in Asteroid Impact Risk Assessment

    Science.gov (United States)

    Mathias, D.; Wheeler, L.; Prabhu, D. K.; Aftosmis, M.; Dotson, J.; Robertson, D. K.

    2015-12-01

    The Engineering Risk Assessment (ERA) team at NASA Ames Research Center is developing a physics-based impact risk model for probabilistically assessing threats from potential asteroid impacts on Earth. The model integrates probabilistic sampling of asteroid parameter ranges with physics-based analyses of entry, breakup, and impact to estimate damage areas and casualties from various impact scenarios. Assessing these threats is a highly coupled, dynamic problem involving significant uncertainties in the range of expected asteroid characteristics, how those characteristics may affect the level of damage, and the fidelity of various modeling approaches and assumptions. The presented model is used to explore the sensitivity of impact risk estimates to these uncertainties in order to gain insight into what additional data or modeling refinements are most important for producing effective, meaningful risk assessments. In the extreme cases of very small or very large impacts, the results are generally insensitive to many of the characterization and modeling assumptions. However, the nature of the sensitivity can change across moderate-sized impacts. Results will focus on the value of additional information in this critical, mid-size range, and how this additional data can support more robust mitigation decisions.

  8. Nonlinear Uncertainty Propagation of Satellite State Error for Tracking and Conjunction Risk Assessment

    Science.gov (United States)

    2017-12-18

    AFRL-RV-PS- AFRL-RV-PS- TR-2017-0177 TR-2017-0177 NONLINEAR UNCERTAINTY PROPAGATION OF SATELLITE STATE ERROR FOR TRACKING AND CONJUNCTION RISK...Uncertainty Propagation of Satellite State Error for Tracking and Conjunction Risk Assessment 5a. CONTRACT NUMBER FA9453-16-1-0084 5b. GRANT NUMBER...prediction and satellite conjunction analysis. Statistical approach utilizes novel methods to build better uncertainty state characterization in the context

  9. Risk Worth Taking - Entrepreneurial Behaviour When Faced with Risk and Uncertainty

    DEFF Research Database (Denmark)

    Zichella, Giulio

    theory suggests differences in risk taking due to individual characteristics. However, entrepreneurship theory did not provide empirical support for such differences. Using data from a laboratory experiment with simple money games, we observe how individuals from two different groups (entrepreneurial......-oriented, non-entrepreneurial-oriented) react to different degrees of risk and uncertainty when real monetary incentives are involved in each decision. The analysis reveals significant differences between entrepreneurial and non-entrepreneurial-oriented individuals in their decision making. In particular...

  10. Climate change, uncertainty and investment in flood risk reduction

    OpenAIRE

    Pol, van der, T.D.

    2015-01-01

    Economic analysis of flood risk management strategies has become more complex due to climate change. This thesis investigates the impact of climate change on investment in flood risk reduction, and applies optimisation methods to support identification of optimal flood risk management strategies. Chapter 2 provides an overview of cost-benefit analysis (CBA) of flood risk management strategies under climate change uncertainty and new information. CBA is applied to determine optimal dike height...

  11. Divide and Conquer: A Valid Approach for Risk Assessment and Decision Making under Uncertainty for Groundwater-Related Diseases

    Science.gov (United States)

    Sanchez-Vila, X.; de Barros, F.; Bolster, D.; Nowak, W.

    2010-12-01

    Assessing the potential risk of hydro(geo)logical supply systems to human population is an interdisciplinary field. It relies on the expertise in fields as distant as hydrogeology, medicine, or anthropology, and needs powerful translation concepts to provide decision support and policy making. Reliable health risk estimates need to account for the uncertainties in hydrological, physiological and human behavioral parameters. We propose the use of fault trees to address the task of probabilistic risk analysis (PRA) and to support related management decisions. Fault trees allow decomposing the assessment of health risk into individual manageable modules, thus tackling a complex system by a structural “Divide and Conquer” approach. The complexity within each module can be chosen individually according to data availability, parsimony, relative importance and stage of analysis. The separation in modules allows for a true inter- and multi-disciplinary approach. This presentation highlights the three novel features of our work: (1) we define failure in terms of risk being above a threshold value, whereas previous studies used auxiliary events such as exceedance of critical concentration levels, (2) we plot an integrated fault tree that handles uncertainty in both hydrological and health components in a unified way, and (3) we introduce a new form of stochastic fault tree that allows to weaken the assumption of independent subsystems that is required by a classical fault tree approach. We illustrate our concept in a simple groundwater-related setting.

  12. Can Bayesian Belief Networks help tackling conceptual model uncertainties in contaminated site risk assessment?

    DEFF Research Database (Denmark)

    Troldborg, Mads; Thomsen, Nanna Isbak; McKnight, Ursula S.

    different conceptual models may describe the same contaminated site equally well. In many cases, conceptual model uncertainty has been shown to be one of the dominant sources for uncertainty and is therefore essential to account for when quantifying uncertainties in risk assessments. We present here......A key component in risk assessment of contaminated sites is the formulation of a conceptual site model. The conceptual model is a simplified representation of reality and forms the basis for the mathematical modelling of contaminant fate and transport at the site. A conceptual model should...... a Bayesian Belief Network (BBN) approach for evaluating the uncertainty in risk assessment of groundwater contamination from contaminated sites. The approach accounts for conceptual model uncertainty by considering multiple conceptual models, each of which represents an alternative interpretation of the site...

  13. On the influence of uncertainties in estimating risk aversion and working interest

    International Nuclear Information System (INIS)

    MacKay, J.A.; Lerche, I.

    1996-01-01

    The influence of uncertainties in costs, value, success probability, risk tolerance and mandated working interest are evaluated for their impact on assessing probable ranges of uncertainty on risk adjusted value, RAV, using different models. The relative importance of different factors in contributing to the uncertainty in RAV is analyzed, as is the influence of different probability distributions for the intrinsic variables entering the RAV model formulae. Numerical illustrations indicate how the RAV probabilities depend not only on the model functions (Cozzolino, hyperbolic tangent) used to provide RAV estimates, but also on the intrinsic shapes of the probability distributions from which are drawn input parameter values for Monte Carlo simulations. In addition, a mandated range of working interest can be addressed as an extra variable contributing to the probabilistic range of RAV; while negative RAV values for high-cost project can be used to assess the probable buy-out amount one should be prepared to pay depending on corporate risk philosophy. Also, the procedures illustrate how the relative contributions of scientific factors influence uncertainty of reserve assessments, allowing one to determine where to concentrate effort to improve the ranges of uncertainty. (Author)

  14. A new approach to reduce uncertainties in space radiation cancer risk predictions.

    Directory of Open Access Journals (Sweden)

    Francis A Cucinotta

    Full Text Available The prediction of space radiation induced cancer risk carries large uncertainties with two of the largest uncertainties being radiation quality and dose-rate effects. In risk models the ratio of the quality factor (QF to the dose and dose-rate reduction effectiveness factor (DDREF parameter is used to scale organ doses for cosmic ray proton and high charge and energy (HZE particles to a hazard rate for γ-rays derived from human epidemiology data. In previous work, particle track structure concepts were used to formulate a space radiation QF function that is dependent on particle charge number Z, and kinetic energy per atomic mass unit, E. QF uncertainties where represented by subjective probability distribution functions (PDF for the three QF parameters that described its maximum value and shape parameters for Z and E dependences. Here I report on an analysis of a maximum QF parameter and its uncertainty using mouse tumor induction data. Because experimental data for risks at low doses of γ-rays are highly uncertain which impacts estimates of maximum values of relative biological effectiveness (RBEmax, I developed an alternate QF model, denoted QFγAcute where QFs are defined relative to higher acute γ-ray doses (0.5 to 3 Gy. The alternate model reduces the dependence of risk projections on the DDREF, however a DDREF is still needed for risk estimates for high-energy protons and other primary or secondary sparsely ionizing space radiation components. Risk projections (upper confidence levels (CL for space missions show a reduction of about 40% (CL∼50% using the QFγAcute model compared the QFs based on RBEmax and about 25% (CL∼35% compared to previous estimates. In addition, I discuss how a possible qualitative difference leading to increased tumor lethality for HZE particles compared to low LET radiation and background tumors remains a large uncertainty in risk estimates.

  15. Risk, rationality, and regret: responding to the uncertainty of childhood food anaphylaxis.

    Science.gov (United States)

    Hu, W; Kerridge, I; Kemp, A

    2005-06-01

    Risk and uncertainty are unavoidable in clinical medicine. In the case of childhood food allergy, the dysphoric experience of uncertainty is heightened by the perception of unpredictable danger to young children. Medicine has tended to respond to uncertainty with forms of rational decision making. Rationality cannot, however, resolve uncertainty and provides an insufficient account of risk. This paper compares the medical and parental accounts of two peanut allergic toddlers to highlight the value of emotions in decision making. One emotion in particular, regret, assists in explaining the actions taken to prevent allergic reactions, given the diffuse nature of responsibility for children. In this light, the assumption that doctors make rational judgments while patients have emotion led preferences is a false dichotomy. Reconciling medical and lay accounts requires acknowledgement of the interrelationship between the rational and the emotional, and may lead to more appropriate clinical decision making under conditions of uncertainty.

  16. Uncertainty assessment of urban pluvial flood risk in a context of climate change adaptation decision making

    DEFF Research Database (Denmark)

    Arnbjerg-Nielsen, Karsten; Zhou, Qianqian

    2014-01-01

    uncertainty analysis, which can assess and quantify the overall uncertainty in relation to climate change adaptation to urban flash floods. The analysis is based on an uncertainty cascade that by means of Monte Carlo simulations of flood risk assessments incorporates climate change impacts as a key driver......There has been a significant increase in climatic extremes in many regions. In Central and Northern Europe, this has led to more frequent and more severe floods. Along with improved flood modelling technologies this has enabled development of economic assessment of climate change adaptation...... to increasing urban flood risk. Assessment of adaptation strategies often requires a comprehensive risk-based economic analysis of current risk, drivers of change of risk over time, and measures to reduce the risk. However, such studies are often associated with large uncertainties. The uncertainties arise from...

  17. Integrated Risk-Capability Analysis under Deep Uncertainty : An ESDMA Approach

    NARCIS (Netherlands)

    Pruyt, E.; Kwakkel, J.H.

    2012-01-01

    Integrated risk-capability analysis methodologies for dealing with increasing degrees of complexity and deep uncertainty are urgently needed in an ever more complex and uncertain world. Although scenario approaches, risk assessment methods, and capability analysis methods are used, few organizations

  18. Priority setting in health care: disentangling risk aversion from inequality aversion.

    Science.gov (United States)

    Echazu, Luciana; Nocetti, Diego

    2013-06-01

    In this paper, we introduce a tractable social welfare function that is rich enough to disentangle attitudes towards risk in health outcomes from attitudes towards health inequalities across individuals. Given this preference specification, we evaluate how the introduction of uncertainty over the severity of illness and over the effectiveness of treatments affects the optimal allocation of healthcare resources. We show that the way in which uncertainty affects the optimal allocation within our proposed specification may differ sharply from that in the standard expected utility framework. Copyright © 2012 John Wiley & Sons, Ltd.

  19. Learning Risk-Taking and Coping with Uncertainty through Experiential, Team-Based Entrepreneurship Education

    Science.gov (United States)

    Arpiainen, Riitta-Liisa; Kurczewska, Agnieszka

    2017-01-01

    This empirical study investigates how students' perceptions of risk-taking and coping with uncertainty change while they are exposed to experience-based entrepreneurship education. The aim of the study is twofold. First, the authors set out to identify the dynamics of entrepreneurial thinking among students experiencing risk and uncertainty while…

  20. Hydroclimatic risks and uncertainty in the global power sector

    Science.gov (United States)

    Gidden, Matthew; Byers, Edward; Greve, Peter; Kahil, Taher; Parkinson, Simon; Raptis, Catherine; Rogelj, Joeri; Satoh, Yusuke; van Vliet, Michelle; Wada, Yoshide; Krey, Volker; Langan, Simon; Riahi, Keywan

    2017-04-01

    Approximately 80% of the world's electricity supply depends on reliable water resources. Thermoelectric and hydropower plants have been impacted by low flows and floods in recent years, notably in the US, Brazil, France, and China, amongst other countries. The dependence on reliable flows imputes a large vulnerability to the electricity supply system due to hydrological variability and the impacts of climate change. Using an updated dataset of global electricity capacity with global climate and hydrological data from the ISI-MIP project, we present an overview analysis of power sector vulnerability to hydroclimatic risks, including low river flows and peak flows. We show how electricity generation in individual countries and transboundary river basins can be impacted, helping decision-makers identify key at-risk geographical regions. Furthermore, our use of a multi-model ensemble of climate and hydrological models allows us to quantify the uncertainty of projected impacts, such that basin-level risks and uncertainty can be compared.

  1. Improving default risk prediction using Bayesian model uncertainty techniques.

    Science.gov (United States)

    Kazemi, Reza; Mosleh, Ali

    2012-11-01

    Credit risk is the potential exposure of a creditor to an obligor's failure or refusal to repay the debt in principal or interest. The potential of exposure is measured in terms of probability of default. Many models have been developed to estimate credit risk, with rating agencies dating back to the 19th century. They provide their assessment of probability of default and transition probabilities of various firms in their annual reports. Regulatory capital requirements for credit risk outlined by the Basel Committee on Banking Supervision have made it essential for banks and financial institutions to develop sophisticated models in an attempt to measure credit risk with higher accuracy. The Bayesian framework proposed in this article uses the techniques developed in physical sciences and engineering for dealing with model uncertainty and expert accuracy to obtain improved estimates of credit risk and associated uncertainties. The approach uses estimates from one or more rating agencies and incorporates their historical accuracy (past performance data) in estimating future default risk and transition probabilities. Several examples demonstrate that the proposed methodology can assess default probability with accuracy exceeding the estimations of all the individual models. Moreover, the methodology accounts for potentially significant departures from "nominal predictions" due to "upsetting events" such as the 2008 global banking crisis. © 2012 Society for Risk Analysis.

  2. Reliability, Resilience, and Vulnerability criteria for the evaluation of Human Health Risks

    Science.gov (United States)

    Rodak, C. M.; Silliman, S. E.; Bolster, D.

    2011-12-01

    Understanding the impact of water quality on the health of a general population is challenging due high degrees of uncertainty and variability in hydrological, toxicological and human aspects of the system. Assessment of the impact of changes in water quality of a public water supply is critical to management of that water supply. We propose the use of three different system evaluation criteria: Reliability, Resilience and Vulnerability (RRV) as a tool for assessing the impact of uncertainty in the arrival of contaminant mass through time with respect to human health risks on a variable population. These criteria were first introduced to the water resources community by Hashimoto et al (1982). Most simply one can understand these criteria as the following: Reliability is the likelihood of the system being in a state of success; Resilience is the probability that the system will return to a state of success at t+1 if it is in failure at time step t, and Vulnerability is the severity of failure, which here is defined as the maximum health risk. These concepts are applied to a theoretical example where the water quality at a water supply well varies over time: health impact is considered based on sliding, 30-year windows of exposure to water derived from the well. We apply the methodology, in terms of uncertainty in water quality deviations, to eight simulated breakthrough curves of a contaminant at the well: each curve represents equal mass of contaminant arriving at the well over a 70-year lifetime of the well, but different mass distributions over time. These curves are used to investigate the impact of uncertainty in the distribution through time of the contaminant mass at the well, as well as the initial arrival of the contaminant over the 70-year lifetime of the well. In addition to extending the health risk through time with uncertainty in mass distribution, we incorporate variability in the human population to examine the evolution of the three criteria within

  3. Uncertainty and Decision Making: Examples of Some Possible New Frontiers

    Science.gov (United States)

    Silliman, S. E.; Rodak, C. M.; Bolster, D.; Saavedra, K.; Evans, W.

    2011-12-01

    The concept of decision making under uncertainty for groundwater systems represents an exciting area of research and application. In this presentation, three examples are briefly introduced which represent possible new applications of risk and decision making under uncertainty. In the most classic of the three examples, a probabilistic strategy is considered within the context of management / assessment of proposed changes in land-use in the vicinity of a public water-supply well. Focused on health-risk related to contamination at the well, the analysis includes uncertainties in source location / strength, groundwater flow / transport, human exposure, and human health risk. The second example involves application of Probabilistic Risk Assessment (PRA) to the evaluation of development projects in rural regions of developing countries. PRA combined with Fault Tree Analysis provides a structure for analysis of the impact of data uncertainties on the estimation of health risk resulting from failure of multiple components of new water-resource systems. The third is an extension of the concept of "risk compensation" to the analysis of potential long-term risk associated with new water resource projects. Of direct interest here is the appearance of new risk to the public, such as introduction of new disease pathways or new sources of contamination of the source waters. As a result of limitations on conceptual model and/or limitations on data, this type of risk is often difficult to identify / assess, and is therefore not commonly included in formal decision-making efforts: it may however seriously impact the long-term net benefit of a water resource project. The goal of presenting these three examples is to illustrate the breadth of possible application of uncertainty / risk analyses beyond the more classic applications to groundwater remediation and protection.

  4. [Health care economics, uncertainty and physician-induced demand].

    Science.gov (United States)

    Domenighetti, G; Casabianca, A

    1995-10-21

    The health care market is a very particular one that is mainly characterized by the absence of information and transparency at every level, particularly between the physician-supplier and the patient-consumer. On this market it is up to the physician to evaluate and define the patient's needs and to decide which are the most effective goods for the patient. The determinants of medical prescription are not only related to the health status of the patient, but also to the payment system (fee for services, salary), to physician density, professional uncertainty, the role and status of the physician in his profession, the legal framework which rules the medical profession, and also the information level of the patient. Agency relationship and professional uncertainty are the most relevant determinants of supplier-induced demand. Professional uncertainty inherent in the practice of a stochastic art such as medicine will "always" give an ethical justification for supplier-induced demand or for the pursuit of "maximal" and/or "defensive" care when market competition is perceived by the physician as a threat to his/her income or employment. Time is ripe for consumers and physicians empowerment in the aim to promote better self-management of health and more thoughtful access to care (for consumers) and more evidences based medicine for physicians.

  5. Health and environmental risks of energy systems

    International Nuclear Information System (INIS)

    Hamilton, L.D.

    1984-01-01

    The paper gives four examples of health risk assessments of energy systems: (1) Comparative risk assessment of the health effects of the coal and nuclear fuel cycles. Estimates differ from previous values chiefly by inclusion of ranges of uncertainty, but some coal-cycle numbers were re-estimated. Upper-boundary public disease risks of air pollution from coal-fired plants dominate. Reactors probably account for most of the potential effect of major nuclear accidents. Accidental death rates in electricity generation are low for reactors and higher for coal. (2) Upper-boundary air pollution health risks of existing fossil-fuel-based energy technologies in the United States of America. Preliminary mortality estimates were obtained combining potential impacts of three index pollutants - SO 4 , NO 2 , and CO - as independent measures of risk. Four fuel cycle trajectories leading to three end-uses were analysed. (3) Health risks of acid deposition and other transported air pollutants, carried out as part of an assessment of the US Congress Office of Technology Assessment (OTA) 'Acid Rain and Transported Air Pollutants. (4) Health effects of uranium mill tailings piles. Mortality risk is estimated to be minuscule (8.7x10 -9 average individual lifetime cancer risk from a model mill, compared with 9.5x10 -4 for background radiation). Methods that sum risks over the indefinite future are shown to be unrealistic. As a final example of risk analysis, the cost-effectiveness analysis for proposed EPA standards for radionuclides is shown to be deficient by an analysis concluding that the cost per potential cancer avoided could range from US $70 million to US $140 billion

  6. Information Uncertainty to Compare Qualitative Reasoning Security Risk Assessment Results

    Energy Technology Data Exchange (ETDEWEB)

    Chavez, Gregory M [Los Alamos National Laboratory; Key, Brian P [Los Alamos National Laboratory; Zerkle, David K [Los Alamos National Laboratory; Shevitz, Daniel W [Los Alamos National Laboratory

    2009-01-01

    The security risk associated with malevolent acts such as those of terrorism are often void of the historical data required for a traditional PRA. Most information available to conduct security risk assessments for these malevolent acts is obtained from subject matter experts as subjective judgements. Qualitative reasoning approaches such as approximate reasoning and evidential reasoning are useful for modeling the predicted risk from information provided by subject matter experts. Absent from these approaches is a consistent means to compare the security risk assessment results. Associated with each predicted risk reasoning result is a quantifiable amount of information uncertainty which can be measured and used to compare the results. This paper explores using entropy measures to quantify the information uncertainty associated with conflict and non-specificity in the predicted reasoning results. The measured quantities of conflict and non-specificity can ultimately be used to compare qualitative reasoning results which are important in triage studies and ultimately resource allocation. Straight forward extensions of previous entropy measures are presented here to quantify the non-specificity and conflict associated with security risk assessment results obtained from qualitative reasoning models.

  7. Evaluation of risk impact of changes to Completion Times addressing model and parameter uncertainties

    International Nuclear Information System (INIS)

    Martorell, S.; Martón, I.; Villamizar, M.; Sánchez, A.I.; Carlos, S.

    2014-01-01

    This paper presents an approach and an example of application for the evaluation of risk impact of changes to Completion Times within the License Basis of a Nuclear Power Plant based on the use of the Probabilistic Risk Assessment addressing identification, treatment and analysis of uncertainties in an integrated manner. It allows full development of a three tired approach (Tier 1–3) following the principles of the risk-informed decision-making accounting for uncertainties as proposed by many regulators. Completion Time is the maximum outage time a safety related equipment is allowed to be down, e.g. for corrective maintenance, which is established within the Limiting Conditions for Operation included into Technical Specifications for operation of a Nuclear Power Plant. The case study focuses on a Completion Time change of the Accumulators System of a Nuclear Power Plant using a level 1 PRA. It focuses on several sources of model and parameter uncertainties. The results obtained show the risk impact of the proposed CT change including both types of epistemic uncertainties is small as compared with current safety goals of concern to Tier 1. However, what concerns to Tier 2 and 3, the results obtained show how the use of some traditional and uncertainty importance measures helps in identifying high risky configurations that should be avoided in NPP technical specifications no matter the duration of CT (Tier 2), and other configurations that could take part of a configuration risk management program (Tier 3). - Highlights: • New approach for evaluation of risk impact of changes to Completion Times. • Integrated treatment and analysis of model and parameter uncertainties. • PSA based application to support risk-informed decision-making. • Measures of importance for identification of risky configurations. • Management of important safety issues to accomplish safety goals

  8. [Status Quo, Uncertainties and Trends Analysis of Environmental Risk Assessment for PFASs].

    Science.gov (United States)

    Hao, Xue-wen; Li, Li; Wang, Jie; Cao, Yan; Liu, Jian-guo

    2015-08-01

    This study systematically combed the definition and change of terms, category and application of perfluoroalkyl and polyfluoroalkyl substances (PFASs) in international academic, focusing on the environmental risk and exposure assessment of PFASs, to comprehensively analyze the current status, uncertainties and trends of PFASs' environmental risk assessment. Overall, the risk assessment of PFASs is facing a complicated situation involving complex substance pedigrees, various types, complex derivative relations, confidential business information and risk uncertainties. Although the environmental risk of long-chain PFASs has been widely recognized, the short-chain PFASs and short-chain fluorotelomers as their alternatives still have many research gaps and uncertainties in environmental hazards, environmental fate and exposure risk. The scope of risk control of PFASs in the international community is still worth discussing. Due to trade secrets and market competition, the chemical structure and risk information of PFASs' alternatives are generally lack of openness and transparency. The environmental risk of most fluorinated and non-fluorinated alternatives is not clear. In total, the international research on PFASs risk assessment gradually transfer from long-chain perfluoroalkyl acids (PFAAs) represented by perfluorooctane sulfonic acid (PFOS) and perfluorooctanoic acid (PFOA) to short-chain PFAAs, and then extends to other PFASs. The main problems to be solved urgently and researched continuously are: the environmental hazardous assessment indexes, such as bioaccumulation and environmental migration, optimization method, the environmental release and multimedia environmental fate of short-chain PFASs; the environmental fate of neutral PFASs and the transformation and contribution as precursors of short-chain PFASs; the risk identification and assessment of fluorinated and non-fluorinated alternatives of PFASs.

  9. Management of uncertainties and the role of risk in Andra programme

    International Nuclear Information System (INIS)

    Grevoz, A.

    2004-01-01

    This paper aims at presenting some aspects of the management of uncertainties in the programmes of Andra for the study of a deep geological repository for high level, long-lived wastes. After presenting very briefly the context of risk-management in the French safety rules, it will discuss how Andra has attempted to link the notions of uncertainties and risk in its 'Dossier 2001' for the clay medium, how this could be made compatible with a deterministic safety approach, what feedback it got from this first exercise, and what are the perspectives for future work. (author)

  10. Environmental impact and risk assessments and key factors contributing to the overall uncertainties.

    Science.gov (United States)

    Salbu, Brit

    2016-01-01

    There is a significant number of nuclear and radiological sources that have contributed, are still contributing, or have the potential to contribute to radioactive contamination of the environment in the future. To protect the environment from radioactive contamination, impact and risk assessments are performed prior to or during a release event, short or long term after deposition or prior and after implementation of countermeasures. When environmental impact and risks are assessed, however, a series of factors will contribute to the overall uncertainties. To provide environmental impact and risk assessments, information on processes, kinetics and a series of input variables is needed. Adding problems such as variability, questionable assumptions, gaps in knowledge, extrapolations and poor conceptual model structures, a series of factors are contributing to large and often unacceptable uncertainties in impact and risk assessments. Information on the source term and the release scenario is an essential starting point in impact and risk models; the source determines activity concentrations and atom ratios of radionuclides released, while the release scenario determine the physico-chemical forms of released radionuclides such as particle size distribution, structure and density. Releases will most often contain other contaminants such as metals, and due to interactions, contaminated sites should be assessed as a multiple stressor scenario. Following deposition, a series of stressors, interactions and processes will influence the ecosystem transfer of radionuclide species and thereby influence biological uptake (toxicokinetics) and responses (toxicodynamics) in exposed organisms. Due to the variety of biological species, extrapolation is frequently needed to fill gaps in knowledge e.g., from effects to no effects, from effects in one organism to others, from one stressor to mixtures. Most toxtests are, however, performed as short term exposure of adult organisms

  11. Health care consumerism: incentives, behavior change and uncertainties.

    Science.gov (United States)

    Domaszewicz, Sander; Havlin, Linda; Connolly, Susan

    2010-01-01

    Employers affected by the recession's 2009 peak must press for cost containment in 2010, especially in health care benefits. Encouraging employee consumerism--through consumer-directed health plans and other strategies--can be enhanced by incentives, but federal efforts at health care reform add some element of uncertainty to the consumer-directed solution. This article provides some lessons to guide the course of action for employers considering implementing a consumerist approach to improve employee health and control the cost trend.

  12. An evaluation of the treatment of risk and uncertainties in the IPCC reports on climate change.

    Science.gov (United States)

    Aven, Terje; Renn, Ortwin

    2015-04-01

    Few global threats rival global climate change in scale and potential consequence. The principal international authority assessing climate risk is the Intergovernmental Panel on Climate Change (IPCC). Through repeated assessments the IPCC has devoted considerable effort and interdisciplinary competence to articulating a common characterization of climate risk and uncertainties. We have reviewed the assessment and its foundation for the Fifth Assessment Reports published in 2013 and 2014, in particular the guidance note for lead authors of the fifth IPCC assessment report on consistent treatment of uncertainties. Our analysis shows that the work carried out by the ICPP is short of providing a theoretically and conceptually convincing foundation on the treatment of risk and uncertainties. The main reasons for our assessment are: (i) the concept of risk is given a too narrow definition (a function of consequences and probability/likelihood); and (ii) the reports lack precision in delineating their concepts and methods. The goal of this article is to contribute to improving the handling of uncertainty and risk in future IPCC studies, thereby obtaining a more theoretically substantiated characterization as well as enhanced scientific quality for risk analysis in this area. Several suggestions for how to improve the risk and uncertainty treatment are provided. © 2014 Society for Risk Analysis.

  13. Integration of renewable generation uncertainties into stochastic unit commitment considering reserve and risk: A comparative study

    International Nuclear Information System (INIS)

    Quan, Hao; Srinivasan, Dipti; Khosravi, Abbas

    2016-01-01

    The uncertainties of renewable energy have brought great challenges to power system commitment, dispatches and reserve requirement. This paper presents a comparative study on integration of renewable generation uncertainties into SCUC (stochastic security-constrained unit commitment) considering reserve and risk. Renewable forecast uncertainties are captured by a list of PIs (prediction intervals). A new scenario generation method is proposed to generate scenarios from these PIs. Different system uncertainties are considered as scenarios in the stochastic SCUC problem formulation. Two comparative simulations with single (E1: wind only) and multiple sources of uncertainty (E2: load, wind, solar and generation outages) are investigated. Five deterministic and four stochastic case studies are performed. Different generation costs, reserve strategies and associated risks are compared under various scenarios. Demonstrated results indicate the overall costs of E2 is lower than E1 due to penetration of solar power and the associated risk in deterministic cases of E2 is higher than E1. It implies the superimposed effect of uncertainties during uncertainty integration. The results also demonstrate that power systems run a higher level of risk during peak load hours, and that stochastic models are more robust than deterministic ones. - Highlights: • An extensive comparative study for renewable integration is presented. • A novel scenario generation method is proposed. • Wind and solar uncertainties are represented by a list of prediction intervals. • Unit commitment and dispatch costs are discussed considering reserve and risk.

  14. Deep Uncertainty Surrounding Coastal Flood Risk Projections: A Case Study for New Orleans

    Science.gov (United States)

    Wong, Tony E.; Keller, Klaus

    2017-10-01

    Future sea-level rise drives severe risks for many coastal communities. Strategies to manage these risks hinge on a sound characterization of the uncertainties. For example, recent studies suggest that large fractions of the Antarctic ice sheet (AIS) may rapidly disintegrate in response to rising global temperatures, leading to potentially several meters of sea-level rise during the next few centuries. It is deeply uncertain, for example, whether such an AIS disintegration will be triggered, how much this would increase sea-level rise, whether extreme storm surges intensify in a warming climate, or which emissions pathway future societies will choose. Here, we assess the impacts of these deep uncertainties on projected flooding probabilities for a levee ring in New Orleans, LA. We use 18 scenarios, presenting probabilistic projections within each one, to sample key deeply uncertain future projections of sea-level rise, radiative forcing pathways, storm surge characterization, and contributions from rapid AIS mass loss. The implications of these deep uncertainties for projected flood risk are thus characterized by a set of 18 probability distribution functions. We use a global sensitivity analysis to assess which mechanisms contribute to uncertainty in projected flood risk over the course of a 50-year design life. In line with previous work, we find that the uncertain storm surge drives the most substantial risk, followed by general AIS dynamics, in our simple model for future flood risk for New Orleans.

  15. Probabilistic approach for assessing infants' health risks due to ingestion of nanoscale silver released from consumer products.

    Science.gov (United States)

    Pang, Chengfang; Hristozov, Danail; Zabeo, Alex; Pizzol, Lisa; Tsang, Michael P; Sayre, Phil; Marcomini, Antonio

    2017-02-01

    Silver nanoparticles (n-Ag) are widely used in consumer products and many medical applications because of their unique antibacterial properties. Their use is raising concern about potential human exposures and health effects. Therefore, it is informative to assess the potential human health risks of n-Ag in order to ensure that nanotechnology-based consumer products are deployed in a safe and sustainable way. Even though toxicity studies clearly show the potential hazard of n-Ag, there have been few attempts to integrate hazard and exposure assessments to evaluate risks. The underlying reason for this is the difficulty in characterizing exposure and the lack of toxicity studies essential for human health risk assessment (HHRA). Such data gaps introduce significant uncertainty into the risk assessment process. This study uses probabilistic methods to assess the relative uncertainty and potential risks of n-Ag exposure to infants. In this paper, we estimate the risks for infants potentially exposed to n-Ag through drinking juice or milk from sippy cups or licking baby blankets containing n-Ag. We explicitly evaluate uncertainty and variability contained in available dose-response and exposure data in order to make the risk characterization process transparent. Our results showed that individual margin of exposures for oral exposure to sippy cups and baby blankets containing n-Ag exhibited minimal risk. Copyright © 2016. Published by Elsevier Ltd.

  16. Development of Risk Uncertainty Factors from Historical NASA Projects

    Science.gov (United States)

    Amer, Tahani R.

    2011-01-01

    NASA is a good investment of federal funds and strives to provide the best value to the nation. NASA has consistently budgeted to unrealistic cost estimates, which are evident in the cost growth in many of its programs. In this investigation, NASA has been using available uncertainty factors from the Aerospace Corporation, Air Force, and Booz Allen Hamilton to develop projects risk posture. NASA has no insight into the developmental of these factors and, as demonstrated here, this can lead to unrealistic risks in many NASA Programs and projects (P/p). The primary contribution of this project is the development of NASA missions uncertainty factors, from actual historical NASA projects, to aid cost-estimating as well as for independent reviews which provide NASA senior management with information and analysis to determine the appropriate decision regarding P/p. In general terms, this research project advances programmatic analysis for NASA projects.

  17. Research approaches to address uncertainties in the risk assessment of arsenic in drinking water

    International Nuclear Information System (INIS)

    Hughes, Michael F.; Kenyon, Elaina M.; Kitchin, Kirk T.

    2007-01-01

    Inorganic arsenic (iAs), an environmental drinking water contaminant, is a human toxicant and carcinogen. The public health community has developed recommendations and regulations that limit human exposure to iAs in drinking water. Although there is a vast amount of information available to regulators on the exposure, disposition and the health-related effects of iAs, there is still critical information about the toxicology of this metalloid that is needed. This necessary information includes identification of the chemical species of arsenic that is (are) the active toxicant(s), the mode(s) of action for its various toxicities and information on potentially susceptible populations. Because of these unknown factors, the risk assessment of iAs still incorporates default assumptions, leading to uncertainties in the overall assessment. The characteristics of a scientifically defensible risk assessment for iAs are that it must: (1) quantitatively link exposure and target tissue dose of active metabolites to key events in the mode of action for major health effects and (2) identify sources of variation in susceptibility to arsenic-induced health effects and quantitatively evaluate their impact wherever possible. Integration of research to address these goals will better protect the health of iAs-exposed populations

  18. Risk, uncertainty and prophet: The psychological insights of Frank H. Knight

    Directory of Open Access Journals (Sweden)

    Tim Rakow

    2010-10-01

    Full Text Available Economist Frank H. Knight (1885--1972 is commonly credited with defining the distinction between decisions under ``risk'' (known chance and decisions under ``uncertainty'' (unmeasurable probability in his 1921 book Risk, Uncertainty and Profit. A closer reading of Knight (1921 reveals a host of psychological insights beyond this risk-uncertainty distinction, many of which foreshadow revolutionary advances in psychological decision theory from the latter half of the 20th century. Knight's description of economic decision making shared much with Simon's (1955, 1956 notion of bounded rationality, whereby choice behavior is regulated by cognitive and environmental constraints. Knight described features of risky choice that were to become key components of prospect theory (Kahneman and Tversky, 1979: the reference dependent valuation of outcomes, and the non-linear weighting of probabilities. Knight also discussed several biases in human decision making, and pointed to two systems of reasoning: one quick, intuitive but error prone, and a slower, more deliberate, rule-based system. A discussion of Knight's potential contribution to psychological decision theory emphasises the importance of a historical perspective on theory development, and the potential value of sourcing ideas from other disciplines or from earlier periods of time.

  19. Advances in Financial Risk Management and Economic Policy Uncertainty: An Overview

    NARCIS (Netherlands)

    S.M. Hammoudeh (Shawkat); M.J. McAleer (Michael)

    2014-01-01

    markdownabstract__Abstract__ Financial risk management is difficult at the best of times, but especially so in the presence of economic uncertainty and financial crises. The purpose of this special issue on “Advances in Financial Risk Management and Economic Policy Uncertainty” is to highlight

  20. Allocating risk capital for a brownfields redevelopment project under hydrogeological and financial uncertainty.

    Science.gov (United States)

    Yu, Soonyoung; Unger, Andre J A; Parker, Beth; Kim, Taehee

    2012-06-15

    In this study, we defined risk capital as the contingency fee or insurance premium that a brownfields redeveloper needs to set aside from the sale of each house in case they need to repurchase it at a later date because the indoor air has been detrimentally affected by subsurface contamination. The likelihood that indoor air concentrations will exceed a regulatory level subject to subsurface heterogeneity and source zone location uncertainty is simulated by a physics-based hydrogeological model using Monte Carlo realizations, yielding the probability of failure. The cost of failure is the future value of the house indexed to the stochastic US National Housing index. The risk capital is essentially the probability of failure times the cost of failure with a surcharge to compensate the developer against hydrogeological and financial uncertainty, with the surcharge acting as safety loading reflecting the developers' level of risk aversion. We review five methodologies taken from the actuarial and financial literature to price the risk capital for a highly stylized brownfield redevelopment project, with each method specifically adapted to accommodate our notion of the probability of failure. The objective of this paper is to develop an actuarially consistent approach for combining the hydrogeological and financial uncertainty into a contingency fee that the brownfields developer should reserve (i.e. the risk capital) in order to hedge their risk exposure during the project. Results indicate that the price of the risk capital is much more sensitive to hydrogeological rather than financial uncertainty. We use the Capital Asset Pricing Model to estimate the risk-adjusted discount rate to depreciate all costs to present value for the brownfield redevelopment project. A key outcome of this work is that the presentation of our risk capital valuation methodology is sufficiently generalized for application to a wide variety of engineering projects. Copyright © 2012 Elsevier

  1. Some considerations on the treatment of uncertainties in risk assessment for practical decision making

    International Nuclear Information System (INIS)

    Aven, Terje; Zio, Enrico

    2011-01-01

    This paper discusses the challenges involved in the representation and treatment of uncertainties in risk assessment, taking the point of view of its use in support to decision making. Two main issues are addressed: (1) how to faithfully represent and express the knowledge available to best support the decision making and (2) how to best inform the decision maker. A general risk-uncertainty framework is presented which provides definitions and interpretations of the key concepts introduced. The framework covers probability theory as well as alternative representations of uncertainty, including interval probability, possibility and evidence theory.

  2. Analysis of parameter uncertainties in the assessment of seismic risk for nuclear power plants

    International Nuclear Information System (INIS)

    Yucemen, S.M.

    1981-04-01

    Probabilistic and statistical methods are used to develop a procedure by which the seismic risk at a specific site can be systematically analyzed. The proposed probabilistic procedure provides a consisted method for the modelling, analysis and updating of uncertainties that are involved in the seismic risk analysis for nuclear power plants. Methods are proposed for including these uncertainties in the final value of calculated risks. Two specific case studies are presented in detail to illustrate the application of the probabilistic method of seismic risk evaluation and to investigate the sensitivity of results to different assumptions

  3. Forecasting Investment Risks in Conditions of Uncertainty

    Directory of Open Access Journals (Sweden)

    Andrenko Elena A.

    2017-04-01

    Full Text Available The article is aimed at studying the topical problem of evaluation and forecasting risks of investment activity of enterprises in conditions of uncertainty. Generalizing the researches on qualitative and quantitative methods for evaluating investment risks has helped to reveal certain shortcomings of the proposed approaches, to note in most of the publications there are no results as to any practical application, and to allocate promising directions. On the basis of the theory of fuzzy sets, a model of forecasting the expected risk has been proposed, making use of the Gauss membership function, which has certain advantages over the multi-angular membership functions. Dependences of investment risk from the parameters characterizing the investment project have been obtained. Using the formulas obtained, the total risk of investing in innovation project depending on the boundary conditions has been defined. As the researched target, index of profitability has been selected. The model provides the potential investors and developers with forecasting possible scenarios of investment process to make informed managerial decisions about the appropriateness of introduction and implementation of a project.

  4. Too Risk Averse to Stay Honest? Business Corruption, Uncertainty and Attitudes Toward Risk

    OpenAIRE

    Soreide, T.

    2009-01-01

    The presence of business-corruption provokes firms to make choices between legal business approaches and illegal bribery. The outcome of a chosen strategy will usually be uncertain at the time the decision is made, and a firm's decision will depend partly on its attitude towards risk. Drawing on empirical results about business corruption, this paper describes the risks, uncertainties and benefits attached to bribery, and specifies their impact on firms' propensity to offer bribes. it then de...

  5. Health and environmental risks of energy systems

    International Nuclear Information System (INIS)

    Hamilton, L.D.

    1984-01-01

    This paper gives four examples of health risk assessments of energy systems: (1) Comparative risk assessment of the health effects of the coal and nuclear fuel cycles. Estimates differ from previous values chiefly by inclusion of ranges of uncertainty, but some coal-cycle numbers were re-estimated. Upper-boundary public disease risks of air pollution from coal-fired plants dominate. Reactors probably account for most of the potential effect of major nuclear accidents. Accidental death rates in electricity generation are low for reactors and higher for coal. (2) Upper boundary air pollution health risks of existing fossil-based energy technologies in the United States. Preliminary mortality estimates were obtained combining potential impacts of three index pollutants - SO 4 , NO 2 , and CO - as independent measures of risk. Four fuel cycle trajectories leading to three end-uses were analyzed. Example results: domestic wood burning has substantial potential impact, with an upper boundary exceeding that of coal; upper-boundary air pollution impacts of gas can exceed those of oil, because of NO 2 . (3) Health risks of acid deposition and other transported air pollutants, carried out as part of an assessment of the US Congress Office of Technology Assessment (OTA) Acid Rain and Transported Air Pollutants - Implications for Public Policy. Three scenarios were examined, leading to estimates of 40,000 to 50,000 annual premature deaths, depending on year (1978 vs 2000) and scenario (holding total emissions constant vs 30% reduction). (4) health effects of uranium mill tailings piles. Mortality risk is estimated to be minuscule (8.7 x 10 -9 average individual lifetime cancer risk from a model mill, compared with 9.5 x 10 -4 for background radiation). Methods that sum risks over the indefinite future are shown to be to be unrealistic. 39 references, 7 figures, 15 tables

  6. Risk-sensitive optimal feedback control accounts for sensorimotor behavior under uncertainty.

    Directory of Open Access Journals (Sweden)

    Arne J Nagengast

    2010-07-01

    Full Text Available Many aspects of human motor behavior can be understood using optimality principles such as optimal feedback control. However, these proposed optimal control models are risk-neutral; that is, they are indifferent to the variability of the movement cost. Here, we propose the use of a risk-sensitive optimal controller that incorporates movement cost variance either as an added cost (risk-averse controller or as an added value (risk-seeking controller to model human motor behavior in the face of uncertainty. We use a sensorimotor task to test the hypothesis that subjects are risk-sensitive. Subjects controlled a virtual ball undergoing Brownian motion towards a target. Subjects were required to minimize an explicit cost, in points, that was a combination of the final positional error of the ball and the integrated control cost. By testing subjects on different levels of Brownian motion noise and relative weighting of the position and control cost, we could distinguish between risk-sensitive and risk-neutral control. We show that subjects change their movement strategy pessimistically in the face of increased uncertainty in accord with the predictions of a risk-averse optimal controller. Our results suggest that risk-sensitivity is a fundamental attribute that needs to be incorporated into optimal feedback control models.

  7. Uncertainty analysis in vulnerability estimations for elements at risk- a review of concepts and some examples on landslides

    Science.gov (United States)

    Ciurean, R. L.; Glade, T.

    2012-04-01

    Decision under uncertainty is a constant of everyday life and an important component of risk management and governance. Recently, experts have emphasized the importance of quantifying uncertainty in all phases of landslide risk analysis. Due to its multi-dimensional and dynamic nature, (physical) vulnerability is inherently complex and the "degree of loss" estimates imprecise and to some extent even subjective. Uncertainty analysis introduces quantitative modeling approaches that allow for a more explicitly objective output, improving the risk management process as well as enhancing communication between various stakeholders for better risk governance. This study presents a review of concepts for uncertainty analysis in vulnerability of elements at risk to landslides. Different semi-quantitative and quantitative methods are compared based on their feasibility in real-world situations, hazard dependency, process stage in vulnerability assessment (i.e. input data, model, output), and applicability within an integrated landslide hazard and risk framework. The resulted observations will help to identify current gaps and future needs in vulnerability assessment, including estimation of uncertainty propagation, transferability of the methods, development of visualization tools, but also address basic questions like what is uncertainty and how uncertainty can be quantified or treated in a reliable and reproducible way.

  8. Examining uncertainties in the linkage between global climate change and potential human health impacts in the western USA -- Hexachlorobenzene (HCB) as a case study

    Energy Technology Data Exchange (ETDEWEB)

    McKone, T.E.; Daniels, J.I. [Lawrence Livermore National Lab., CA (United States); Goldman, M. [Univ. of California, Davis, CA (United States)

    1994-09-30

    Industrial societies have altered the earth`s environment in ways that could have important, long-term ecological, economic, and health implications. In this paper the authors define, characterize, and evaluate parameter and outcome uncertainties using a model that links global climate change with predictions of chemical exposure and human health risk in the western region of the US. They illustrate the impact of uncertainty about global climate change on such potential secondary outcomes using as a case study the public health consequences related to the behavior environmentally of hexachlorobenzene (HCB), an ubiquitous multimedia pollutant. They begin by constructing a matrix that reveals the linkage between global environmental change and potential regional human-health effects that might be induced directly and/or indirectly by HCB released into the air and water. This matrix is useful for translating critical uncertainties into terms that can be understood and used by policy makers to formulate strategies against potential adverse irreversible health and economic consequences. Specifically, the authors employ a combined uncertainty/sensitivity analysis to investigate how the HCB that has been released is affected by increasing atmospheric temperature and the accompanying climate alterations that are anticipated and how such uncertainty propagates to affect the expected magnitude and calculational precision of estimates of associated potential human exposures and health effects.

  9. The uncertainty cascade in flood risk assessment under changing climatic conditions - the Biala Tarnowska case study

    Science.gov (United States)

    Doroszkiewicz, Joanna; Romanowicz, Renata

    2016-04-01

    Uncertainty in the results of the hydraulic model is not only associated with the limitations of that model and the shortcomings of data. An important factor that has a major impact on the uncertainty of the flood risk assessment in a changing climate conditions is associated with the uncertainty of future climate scenarios (IPCC WG I, 2013). Future climate projections provided by global climate models are used to generate future runoff required as an input to hydraulic models applied in the derivation of flood risk maps. Biala Tarnowska catchment, situated in southern Poland is used as a case study. Future discharges at the input to a hydraulic model are obtained using the HBV model and climate projections obtained from the EUROCORDEX project. The study describes a cascade of uncertainty related to different stages of the process of derivation of flood risk maps under changing climate conditions. In this context it takes into account the uncertainty of future climate projections, an uncertainty of flow routing model, the propagation of that uncertainty through the hydraulic model, and finally, the uncertainty related to the derivation of flood risk maps. One of the aims of this study is an assessment of a relative impact of different sources of uncertainty on the uncertainty of flood risk maps. Due to the complexity of the process, an assessment of total uncertainty of maps of inundation probability might be very computer time consuming. As a way forward we present an application of a hydraulic model simulator based on a nonlinear transfer function model for the chosen locations along the river reach. The transfer function model parameters are estimated based on the simulations of the hydraulic model at each of the model cross-section. The study shows that the application of the simulator substantially reduces the computer requirements related to the derivation of flood risk maps under future climatic conditions. Acknowledgements: This work was supported by the

  10. Emerging Radiation Health-Risk Mitigation Technologies

    International Nuclear Information System (INIS)

    Wilson, J.W.; Cucinotta, F.A.; Schimmerling, W.

    2004-01-01

    Past space missions beyond the confines of the Earth's protective magnetic field have been of short duration and protection from the effects of solar particle events was of primary concern. The extension of operational infrastructure beyond low-Earth orbit to enable routine access to more interesting regions of space will require protection from the hazards of the accumulated exposures of Galactic Cosmic Rays (GCR). There are significant challenges in providing protection from the long-duration exposure to GCR: the human risks to the exposures are highly uncertain and safety requirements places unreasonable demands in supplying sufficient shielding materials in the design. A vigorous approach to future radiation health-risk mitigation requires a triage of techniques (using biological and technical factors) and reduction of the uncertainty in radiation risk models. The present paper discusses the triage of factors for risk mitigation with associated materials issues and engineering design methods

  11. County-Level Climate Uncertainty for Risk Assessments: Volume 1.

    Energy Technology Data Exchange (ETDEWEB)

    Backus, George A.; Lowry, Thomas Stephen; Jones, Shannon M; Walker, La Tonya Nicole; Roberts, Barry L; Malczynski, Leonard A.

    2017-06-01

    This report uses the CMIP5 series of climate model simulations to produce country- level uncertainty distributions for use in socioeconomic risk assessments of climate change impacts. It provides appropriate probability distributions, by month, for 169 countries and autonomous-areas on temperature, precipitation, maximum temperature, maximum wind speed, humidity, runoff, soil moisture and evaporation for the historical period (1976-2005), and for decadal time periods to 2100. It also provides historical and future distributions for the Arctic region on ice concentration, ice thickness, age of ice, and ice ridging in 15-degree longitude arc segments from the Arctic Circle to 80 degrees latitude, plus two polar semicircular regions from 80 to 90 degrees latitude. The uncertainty is meant to describe the lack of knowledge rather than imprecision in the physical simulation because the emphasis is on unfalsified risk and its use to determine potential socioeconomic impacts. The full report is contained in 27 volumes.

  12. Uncertainties associated with geologic disposal of high-level radioactive waste

    International Nuclear Information System (INIS)

    Kocher, D.C.; Sjoreen, A.L.; Bard, C.S.; Olsen, C.R.

    1982-01-01

    This paper focuses on uncertainties associated with models for predicting: (1) groundwater transport of radionuclides between a repository and the biosphere; and (2) long-term collective dose and health effects following release of long-lived radionuclides to the biosphere. We do not present numerical estimates of uncertainties in such predictions. Rather, we emphasize the various sources of uncertainty and attempt to evaluate the extent to which current models and supporting data bases can realistically describe long-term repository performance and health risks. We do not consider uncertainties associated with the long-term performance of engineered barriers at a repository or with human intrusion

  13. Interpretations of alternative uncertainty representations in a reliability and risk analysis context

    International Nuclear Information System (INIS)

    Aven, T.

    2011-01-01

    Probability is the predominant tool used to measure uncertainties in reliability and risk analyses. However, other representations also exist, including imprecise (interval) probability, fuzzy probability and representations based on the theories of evidence (belief functions) and possibility. Many researchers in the field are strong proponents of these alternative methods, but some are also sceptical. In this paper, we address one basic requirement set for quantitative measures of uncertainty: the interpretation needed to explain what an uncertainty number expresses. We question to what extent the various measures meet this requirement. Comparisons are made with probabilistic analysis, where uncertainty is represented by subjective probabilities, using either a betting interpretation or a reference to an uncertainty standard interpretation. By distinguishing between chances (expressing variation) and subjective probabilities, new insights are gained into the link between the alternative uncertainty representations and probability.

  14. Emotion and decision-making under uncertainty: Physiological arousal predicts increased gambling during ambiguity but not risk.

    Science.gov (United States)

    FeldmanHall, Oriel; Glimcher, Paul; Baker, Augustus L; Phelps, Elizabeth A

    2016-10-01

    Uncertainty, which is ubiquitous in decision-making, can be fractionated into known probabilities (risk) and unknown probabilities (ambiguity). Although research has illustrated that individuals more often avoid decisions associated with ambiguity compared to risk, it remains unclear why ambiguity is perceived as more aversive. Here we examine the role of arousal in shaping the representation of value and subsequent choice under risky and ambiguous decisions. To investigate the relationship between arousal and decisions of uncertainty, we measure skin conductance response-a quantifiable measure reflecting sympathetic nervous system arousal-during choices to gamble under risk and ambiguity. To quantify the discrete influences of risk and ambiguity sensitivity and the subjective value of each option under consideration, we model fluctuating uncertainty, as well as the amount of money that can be gained by taking the gamble. Results reveal that although arousal tracks the subjective value of a lottery regardless of uncertainty type, arousal differentially contributes to the computation of value-that is, choice-depending on whether the uncertainty is risky or ambiguous: Enhanced arousal adaptively decreases risk-taking only when the lottery is highly risky but increases risk-taking when the probability of winning is ambiguous (even after controlling for subjective value). Together, this suggests that the role of arousal during decisions of uncertainty is modulatory and highly dependent on the context in which the decision is framed. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  15. Epistemic uncertainties and natural hazard risk assessment - Part 1: A review of the issues

    Science.gov (United States)

    Beven, K. J.; Aspinall, W. P.; Bates, P. D.; Borgomeo, E.; Goda, K.; Hall, J. W.; Page, T.; Phillips, J. C.; Rougier, J. T.; Simpson, M.; Stephenson, D. B.; Smith, P. J.; Wagener, T.; Watson, M.

    2015-12-01

    Uncertainties in natural hazard risk assessment are generally dominated by the sources arising from lack of knowledge or understanding of the processes involved. There is a lack of knowledge about frequencies, process representations, parameters, present and future boundary conditions, consequences and impacts, and the meaning of observations in evaluating simulation models. These are the epistemic uncertainties that can be difficult to constrain, especially in terms of event or scenario probabilities, even as elicited probabilities rationalized on the basis of expert judgements. This paper reviews the issues raised by trying to quantify the effects of epistemic uncertainties. Such scientific uncertainties might have significant influence on decisions that are made for risk management, so it is important to communicate the meaning of an uncertainty estimate and to provide an audit trail of the assumptions on which it is based. Some suggestions for good practice in doing so are made.

  16. Health risks of passive smoking.

    Science.gov (United States)

    Papier, C M; Stellman, S D

    1986-01-01

    Passive or involuntary smoking is the inhalation of smoke which escapes directly into the air from the lit end of a burning cigarette. This unfiltered smoke contains the same toxic components of the mainstream smoke inhaled directly by the smoker, including numerous carcinogens, many in greater concentrations. It has long been known that exposure to this type of smoke leads to increased respiratory and other adverse health conditions in non-smokers, especially children. During the past five years, evidence has been accumulating that risk of lung cancer is also higher, particularly in non-smoking women whose husbands smoke. Despite uncertainties and differences in interpretation of various cancer studies, there is ample justification for public health measures now in place or proposed, such as restriction or elimination of smoking in the workplace and in public places.

  17. Assessment of volcanic hazards, vulnerability, risk and uncertainty (Invited)

    Science.gov (United States)

    Sparks, R. S.

    2009-12-01

    many sources of uncertainty in forecasting the areas that volcanic activity will effect and the severity of the effects. Uncertainties arise from: natural variability, inadequate data, biased data, incomplete data, lack of understanding of the processes, limitations to predictive models, ambiguity, and unknown unknowns. The description of volcanic hazards is thus necessarily probabilistic and requires assessment of the attendant uncertainties. Several issues arise from the probabilistic nature of volcanic hazards and the intrinsic uncertainties. Although zonation maps require well-defined boundaries for administrative pragmatism, such boundaries cannot divide areas that are completely safe from those that are unsafe. Levels of danger or safety need to be defined to decide on and justify boundaries through the concepts of vulnerability and risk. More data, better observations, improved models may reduce uncertainties, but can increase uncertainties and may lead to re-appraisal of zone boundaries. Probabilities inferred by statistical techniques are hard to communicate. Expert elicitation is an emerging methodology for risk assessment and uncertainty evaluation. The method has been applied at one major volcanic crisis (Soufrière Hills Volcano, Montserrat), and is being applied in planning for volcanic crises at Vesuvius.

  18. Risk Analysis for Environmental Health Triage

    International Nuclear Information System (INIS)

    Bogen, K T

    2005-01-01

    The Homeland Security Act mandates development of a national, risk-based system to support planning for, response to and recovery from emergency situations involving large-scale toxic exposures. To prepare for and manage consequences effectively, planners and responders need not only to identify zones of potentially elevated individual risk, but also to predict expected casualties. Emergency response support systems now define ''consequences'' by mapping areas in which toxic chemical concentrations do or may exceed Acute Exposure Guideline Levels (AEGLs) or similar guidelines. However, because AEGLs do not estimate expected risks, current unqualified claims that such maps support consequence management are misleading. Intentionally protective, AEGLs incorporate various safety/uncertainty factors depending on scope and quality of chemical-specific toxicity data. Some of these factors are irrelevant, and others need to be modified, whenever resource constraints or exposure-scenario complexities require responders to make critical trade-off (triage) decisions in order to minimize expected casualties. AEGL-exceedance zones cannot consistently be aggregated, compared, or used to calculate expected casualties, and so may seriously misguide emergency response triage decisions. Methods and tools well established and readily available to support environmental health protection are not yet developed for chemically related environmental health triage. Effective triage decisions involving chemical risks require a new assessment approach that focuses on best estimates of likely casualties, rather than on upper plausible bounds of individual risk. If risk-based consequence management is to become a reality, federal agencies tasked with supporting emergency response must actively coordinate to foster new methods that can support effective environmental health triage

  19. Quantifying aggregated uncertainty in Plasmodium falciparum malaria prevalence and populations at risk via efficient space-time geostatistical joint simulation.

    Science.gov (United States)

    Gething, Peter W; Patil, Anand P; Hay, Simon I

    2010-04-01

    Risk maps estimating the spatial distribution of infectious diseases are required to guide public health policy from local to global scales. The advent of model-based geostatistics (MBG) has allowed these maps to be generated in a formal statistical framework, providing robust metrics of map uncertainty that enhances their utility for decision-makers. In many settings, decision-makers require spatially aggregated measures over large regions such as the mean prevalence within a country or administrative region, or national populations living under different levels of risk. Existing MBG mapping approaches provide suitable metrics of local uncertainty--the fidelity of predictions at each mapped pixel--but have not been adapted for measuring uncertainty over large areas, due largely to a series of fundamental computational constraints. Here the authors present a new efficient approximating algorithm that can generate for the first time the necessary joint simulation of prevalence values across the very large prediction spaces needed for global scale mapping. This new approach is implemented in conjunction with an established model for P. falciparum allowing robust estimates of mean prevalence at any specified level of spatial aggregation. The model is used to provide estimates of national populations at risk under three policy-relevant prevalence thresholds, along with accompanying model-based measures of uncertainty. By overcoming previously unchallenged computational barriers, this study illustrates how MBG approaches, already at the forefront of infectious disease mapping, can be extended to provide large-scale aggregate measures appropriate for decision-makers.

  20. Managing structural uncertainty in health economic decision models: a discrepancy approach

    OpenAIRE

    Strong, M.; Oakley, J.; Chilcott, J.

    2012-01-01

    Healthcare resource allocation decisions are commonly informed by computer model predictions of population mean costs and health effects. It is common to quantify the uncertainty in the prediction due to uncertain model inputs, but methods for quantifying uncertainty due to inadequacies in model structure are less well developed. We introduce an example of a model that aims to predict the costs and health effects of a physical activity promoting intervention. Our goal is to develop a framewor...

  1. Adaptive Governance, Uncertainty, and Risk: Policy Framing and Responses to Climate Change, Drought, and Flood.

    Science.gov (United States)

    Hurlbert, Margot; Gupta, Joyeeta

    2016-02-01

    As climate change impacts result in more extreme events (such as droughts and floods), the need to understand which policies facilitate effective climate change adaptation becomes crucial. Hence, this article answers the question: How do governments and policymakers frame policy in relation to climate change, droughts, and floods and what governance structures facilitate adaptation? This research interrogates and analyzes through content analysis, supplemented by semi-structured qualitative interviews, the policy response to climate change, drought, and flood in relation to agricultural producers in four case studies in river basins in Chile, Argentina, and Canada. First, an epistemological explanation of risk and uncertainty underscores a brief literature review of adaptive governance, followed by policy framing in relation to risk and uncertainty, and an analytical model is developed. Pertinent findings of the four cases are recounted, followed by a comparative analysis. In conclusion, recommendations are made to improve policies and expand adaptive governance to better account for uncertainty and risk. This article is innovative in that it proposes an expanded model of adaptive governance in relation to "risk" that can help bridge the barrier of uncertainty in science and policy. © 2015 Society for Risk Analysis.

  2. An overview of the risk uncertainty assessment process for the Cassini space mission

    International Nuclear Information System (INIS)

    Wyss, G.D.

    1996-01-01

    The Cassini spacecraft is a deep space probe whose mission is to explore the planet Saturn and its moons. Since the spacecraft's electrical requirements will be supplied by radioisotope thermoelectric generators (RTGs), the spacecraft designers and mission planners must assure that potential accidents involving the spacecraft do not pose significant human risk. The Cassini risk analysis team is seeking to perform a quantitative uncertainty analysis as a part of the overall mission risk assessment program. This paper describes the uncertainty analysis methodology to be used for the Cassini mission and compares it to the methods that were originally developed for evaluation of commercial nuclear power reactors

  3. Practical consequences of the assessment of different energy health risks

    International Nuclear Information System (INIS)

    Hamilton, L.D.

    1984-01-01

    Public authorities must make decisions about energy, and the risks of alternative strategies need to be calculated including health and environmental costs. Information from various sources must be organized into a logical framework for comparing impacts. This must include the widest practicable range of health and environmental damage - public health impact of pollution, role of accidents, disease and hazardous materials in the workplace, and odds for catastrophes. It must put each part of the energy cycle into perspective - giving particular attention to uncertainties in knowledge - to convey what is known, what is uncertain, and the importance of each factor in the overall picture. This paper gives examples of the use of health-impact assessment by decision-makers: (1) comparative risk assessment of the health effects of coal and nuclear fuel cycles used in nuclear power plant siting and licensing hearings, and (2) health risks of acid deposition and other air-transported pollutants, carried out as part of an assessment for the U.S. Congress Office of Technology Assessment. (author)

  4. Worldwide Regulations of Standard Values of Pesticides for Human Health Risk Control: A Review

    Science.gov (United States)

    Jennings, Aaron

    2017-01-01

    The impact of pesticide residues on human health is a worldwide problem, as human exposure to pesticides can occur through ingestion, inhalation, and dermal contact. Regulatory jurisdictions have promulgated the standard values for pesticides in residential soil, air, drinking water, and agricultural commodity for years. Until now, more than 19,400 pesticide soil regulatory guidance values (RGVs) and 5400 pesticide drinking water maximum concentration levels (MCLs) have been regulated by 54 and 102 nations, respectively. Over 90 nations have provided pesticide agricultural commodity maximum residue limits (MRLs) for at least one of the 12 most commonly consumed agricultural foods. A total of 22 pesticides have been regulated with more than 100 soil RGVs, and 25 pesticides have more than 100 drinking water MCLs. This research indicates that those RGVs and MCLs for an individual pesticide could vary over seven (DDT drinking water MCLs), eight (Lindane soil RGVs), or even nine (Dieldrin soil RGVs) orders of magnitude. Human health risk uncertainty bounds and the implied total exposure mass burden model were applied to analyze the most commonly regulated and used pesticides for human health risk control. For the top 27 commonly regulated pesticides in soil, there are at least 300 RGVs (8% of the total) that are above all of the computed upper bounds for human health risk uncertainty. For the top 29 most-commonly regulated pesticides in drinking water, at least 172 drinking water MCLs (5% of the total) exceed the computed upper bounds for human health risk uncertainty; while for the 14 most widely used pesticides, there are at least 310 computed implied dose limits (28.0% of the total) that are above the acceptable daily intake values. The results show that some worldwide standard values were not derived conservatively enough to avoid human health risk by the pesticides, and that some values were not computed comprehensively by considering all major human exposure

  5. Worldwide Regulations of Standard Values of Pesticides for Human Health Risk Control: A Review.

    Science.gov (United States)

    Li, Zijian; Jennings, Aaron

    2017-07-22

    Abstract : The impact of pesticide residues on human health is a worldwide problem, as human exposure to pesticides can occur through ingestion, inhalation, and dermal contact. Regulatory jurisdictions have promulgated the standard values for pesticides in residential soil, air, drinking water, and agricultural commodity for years. Until now, more than 19,400 pesticide soil regulatory guidance values (RGVs) and 5400 pesticide drinking water maximum concentration levels (MCLs) have been regulated by 54 and 102 nations, respectively. Over 90 nations have provided pesticide agricultural commodity maximum residue limits (MRLs) for at least one of the 12 most commonly consumed agricultural foods. A total of 22 pesticides have been regulated with more than 100 soil RGVs, and 25 pesticides have more than 100 drinking water MCLs. This research indicates that those RGVs and MCLs for an individual pesticide could vary over seven (DDT drinking water MCLs), eight (Lindane soil RGVs), or even nine (Dieldrin soil RGVs) orders of magnitude. Human health risk uncertainty bounds and the implied total exposure mass burden model were applied to analyze the most commonly regulated and used pesticides for human health risk control. For the top 27 commonly regulated pesticides in soil, there are at least 300 RGVs (8% of the total) that are above all of the computed upper bounds for human health risk uncertainty. For the top 29 most-commonly regulated pesticides in drinking water, at least 172 drinking water MCLs (5% of the total) exceed the computed upper bounds for human health risk uncertainty; while for the 14 most widely used pesticides, there are at least 310 computed implied dose limits (28.0% of the total) that are above the acceptable daily intake values. The results show that some worldwide standard values were not derived conservatively enough to avoid human health risk by the pesticides, and that some values were not computed comprehensively by considering all major human

  6. A method for minimum risk portfolio optimization under hybrid uncertainty

    Science.gov (United States)

    Egorova, Yu E.; Yazenin, A. V.

    2018-03-01

    In this paper, we investigate a minimum risk portfolio model under hybrid uncertainty when the profitability of financial assets is described by fuzzy random variables. According to Feng, the variance of a portfolio is defined as a crisp value. To aggregate fuzzy information the weakest (drastic) t-norm is used. We construct an equivalent stochastic problem of the minimum risk portfolio model and specify the stochastic penalty method for solving it.

  7. Human health and safety risks management in underground coal mines using fuzzy TOPSIS

    Energy Technology Data Exchange (ETDEWEB)

    Mahdevari, Satar, E-mail: satar.mahdevari@aut.ac.ir [Department of Mining and Metallurgical Engineering, Amirkabir University of Technology, Tehran (Iran, Islamic Republic of); Shahriar, Kourosh [Department of Mining and Metallurgical Engineering, Amirkabir University of Technology, Tehran (Iran, Islamic Republic of); Esfahanipour, Akbar [Industrial Engineering Department, Amirkabir University of Technology, Tehran (Iran, Islamic Republic of)

    2014-08-01

    The scrutiny of health and safety of personnel working in underground coal mines is heightened because of fatalities and disasters that occur every year worldwide. A methodology based on fuzzy TOPSIS was proposed to assess the risks associated with human health in order to manage control measures and support decision-making, which could provide the right balance between different concerns, such as safety and costs. For this purpose, information collected from three hazardous coal mines namely Hashouni, Hojedk and Babnizu located at the Kerman coal deposit, Iran, were used to manage the risks affecting the health and safety of their miners. Altogether 86 hazards were identified and classified under eight categories: geomechanical, geochemical, electrical, mechanical, chemical, environmental, personal, and social, cultural and managerial risks. Overcoming the uncertainty of qualitative data, the ranking process is accomplished by fuzzy TOPSIS. After running the model, twelve groups with different risks were obtained. Located in the first group, the most important risks with the highest negative effects are: materials falling, catastrophic failure, instability of coalface and immediate roof, firedamp explosion, gas emission, misfire, stopping of ventilation system, wagon separation at inclines, asphyxiation, inadequate training and poor site management system. According to the results, the proposed methodology can be a reliable technique for management of the minatory hazards and coping with uncertainties affecting the health and safety of miners when performance ratings are imprecise. The proposed model can be primarily designed to identify potential hazards and help in taking appropriate measures to minimize or remove the risks before accidents can occur. - Highlights: • Risks associated with health and safety of coal miners were investigated. • A reliable methodology based on Fuzzy TOPSIS was developed to manage the risks. • Three underground mines in Kerman

  8. Human health and safety risks management in underground coal mines using fuzzy TOPSIS

    International Nuclear Information System (INIS)

    Mahdevari, Satar; Shahriar, Kourosh; Esfahanipour, Akbar

    2014-01-01

    The scrutiny of health and safety of personnel working in underground coal mines is heightened because of fatalities and disasters that occur every year worldwide. A methodology based on fuzzy TOPSIS was proposed to assess the risks associated with human health in order to manage control measures and support decision-making, which could provide the right balance between different concerns, such as safety and costs. For this purpose, information collected from three hazardous coal mines namely Hashouni, Hojedk and Babnizu located at the Kerman coal deposit, Iran, were used to manage the risks affecting the health and safety of their miners. Altogether 86 hazards were identified and classified under eight categories: geomechanical, geochemical, electrical, mechanical, chemical, environmental, personal, and social, cultural and managerial risks. Overcoming the uncertainty of qualitative data, the ranking process is accomplished by fuzzy TOPSIS. After running the model, twelve groups with different risks were obtained. Located in the first group, the most important risks with the highest negative effects are: materials falling, catastrophic failure, instability of coalface and immediate roof, firedamp explosion, gas emission, misfire, stopping of ventilation system, wagon separation at inclines, asphyxiation, inadequate training and poor site management system. According to the results, the proposed methodology can be a reliable technique for management of the minatory hazards and coping with uncertainties affecting the health and safety of miners when performance ratings are imprecise. The proposed model can be primarily designed to identify potential hazards and help in taking appropriate measures to minimize or remove the risks before accidents can occur. - Highlights: • Risks associated with health and safety of coal miners were investigated. • A reliable methodology based on Fuzzy TOPSIS was developed to manage the risks. • Three underground mines in Kerman

  9. Impact of Hydrogeological Uncertainty on Estimation of Environmental Risks Posed by Hydrocarbon Transportation Networks

    Science.gov (United States)

    Ciriello, V.; Lauriola, I.; Bonvicini, S.; Cozzani, V.; Di Federico, V.; Tartakovsky, Daniel M.

    2017-11-01

    Ubiquitous hydrogeological uncertainty undermines the veracity of quantitative predictions of soil and groundwater contamination due to accidental hydrocarbon spills from onshore pipelines. Such predictions, therefore, must be accompanied by quantification of predictive uncertainty, especially when they are used for environmental risk assessment. We quantify the impact of parametric uncertainty on quantitative forecasting of temporal evolution of two key risk indices, volumes of unsaturated and saturated soil contaminated by a surface spill of light nonaqueous-phase liquids. This is accomplished by treating the relevant uncertain parameters as random variables and deploying two alternative probabilistic models to estimate their effect on predictive uncertainty. A physics-based model is solved with a stochastic collocation method and is supplemented by a global sensitivity analysis. A second model represents the quantities of interest as polynomials of random inputs and has a virtually negligible computational cost, which enables one to explore any number of risk-related contamination scenarios. For a typical oil-spill scenario, our method can be used to identify key flow and transport parameters affecting the risk indices, to elucidate texture-dependent behavior of different soils, and to evaluate, with a degree of confidence specified by the decision-maker, the extent of contamination and the correspondent remediation costs.

  10. Media reporting of risk information: Uncertainties and the future

    International Nuclear Information System (INIS)

    Peltu, M.

    1988-01-01

    This paper argues that very little is known with a reasonable degree of certainty about how the media influence their audiences. Media effects are mediated through diverse, subtle social interactions and processes. Future changes in the regulatory and technological media environment will create even more uncertainty by changing basic parameters of media/audience interaction. More research is needed to help shed light on these uncertainties and future changes. If this research is to be of relevance to real communicators of real risk, it must fully address the issues of how the media are influenced, not just media impacts. In this context, the role of experts, PR, advertising, and media professionals' motivations are key priorities. (orig.)

  11. Dealing with unquantifiable uncertainties in landslide modelling for urban risk reduction in developing countries

    Science.gov (United States)

    Almeida, Susana; Holcombe, Liz; Pianosi, Francesca; Wagener, Thorsten

    2016-04-01

    Landslides have many negative economic and societal impacts, including the potential for significant loss of life and damage to infrastructure. Slope stability assessment can be used to guide decisions about the management of landslide risk, but its usefulness can be challenged by high levels of uncertainty in predicting landslide occurrence. Prediction uncertainty may be associated with the choice of model that is used to assess slope stability, the quality of the available input data, or a lack of knowledge of how future climatic and socio-economic changes may affect future landslide risk. While some of these uncertainties can be characterised by relatively well-defined probability distributions, for other uncertainties, such as those linked to climate change, no probability distribution is available to characterise them. This latter type of uncertainty, often referred to as deep uncertainty, means that robust policies need to be developed that are expected to perform acceptably well over a wide range of future conditions. In our study the impact of deep uncertainty on slope stability predictions is assessed in a quantitative and structured manner using Global Sensitivity Analysis (GSA) and the Combined Hydrology and Stability Model (CHASM). In particular, we use several GSA methods including the Method of Morris, Regional Sensitivity Analysis and Classification and Regression Trees (CART), as well as advanced visualization tools, to assess the combination of conditions that may lead to slope failure. Our example application is a slope in the Caribbean, an area that is naturally susceptible to landslides due to a combination of high rainfall rates during the hurricane season, steep slopes, and highly weathered residual soils. Rapid unplanned urbanisation and changing climate may further exacerbate landslide risk in the future. Our example shows how we can gain useful information in the presence of deep uncertainty by combining physically based models with GSA in

  12. Uncertainty Analysis of A Flood Risk Mapping Procedure Applied In Urban Areas

    Science.gov (United States)

    Krause, J.; Uhrich, S.; Bormann, H.; Diekkrüger, B.

    In the framework of IRMA-Sponge program the presented study was part of the joint research project FRHYMAP (flood risk and hydrological mapping). A simple con- ceptual flooding model (FLOODMAP) has been developed to simulate flooded areas besides rivers within cities. FLOODMAP requires a minimum of input data (digital el- evation model (DEM), river line, water level plain) and parameters and calculates the flood extent as well as the spatial distribution of flood depths. of course the simulated model results are affected by errors and uncertainties. Possible sources of uncertain- ties are the model structure, model parameters and input data. Thus after the model validation (comparison of simulated water to observed extent, taken from airborne pictures) the uncertainty of the essential input data set (digital elevation model) was analysed. Monte Carlo simulations were performed to assess the effect of uncertain- ties concerning the statistics of DEM quality and to derive flooding probabilities from the set of simulations. The questions concerning a minimum resolution of a DEM re- quired for flood simulation and concerning the best aggregation procedure of a given DEM was answered by comparing the results obtained using all available standard GIS aggregation procedures. Seven different aggregation procedures were applied to high resolution DEMs (1-2m) in three cities (Bonn, Cologne, Luxembourg). Basing on this analysis the effect of 'uncertain' DEM data was estimated and compared with other sources of uncertainties. Especially socio-economic information and monetary transfer functions required for a damage risk analysis show a high uncertainty. There- fore this study helps to analyse the weak points of the flood risk and damage risk assessment procedure.

  13. Framing risk and uncertainty in social science articles on climate change, 1995–2012

    OpenAIRE

    Shaw, Chris; Hellsten, Iina; Nerlich, Brigitte

    2016-01-01

    The issue of climate change is intimately linked to notions of risk and uncertainty, concepts that pose challenges to climate science, climate change communication, and science-society interactions. While a large majority of climate scientists are increasingly certain about the causes of climate change and the risks posed by its impacts (see IPCC, 2013 and 2014), public perception of climate change is still largely framed by uncertainty, especially regarding impacts (Poortinga et al., 2011). ...

  14. Assessing risks and uncertainties in forest dynamics under different management scenarios and climate change

    Directory of Open Access Journals (Sweden)

    Matthias Albert

    2015-05-01

    Full Text Available Background Forest management faces a climate induced shift in growth potential and increasing current and emerging new risks. Vulnerability analysis provides decision support based on projections of natural resources taking risks and uncertainties into account. In this paper we (1 characterize differences in forest dynamics under three management scenarios, (2 analyse the effects of the three scenarios on two risk factors, windthrow and drought stress, and (3 quantify the effects and the amount of uncertainty arising from climate projections on height increment and drought stress. Methods In four regions in northern Germany, we apply three contrasting management scenarios and project forest development under climate change until 2070. Three climate runs (minimum, median, maximum based on the emission scenario RCP 8.5 control the site-sensitive forest growth functions. The minimum and maximum climate run define the range of prospective climate development. Results The projections of different management regimes until 2070 show the diverging medium-term effects of thinnings and harvests and long-term effects of species conversion on a regional scale. Examples of windthrow vulnerability and drought stress reveal how adaptation measures depend on the applied management path and the decision-maker’s risk attitude. Uncertainty analysis shows the increasing variability of drought risk projections with time. The effect of climate projections on height growth are quantified and uncertainty analysis reveals that height growth of young trees is dominated by the age-trend whereas the climate signal in height increment of older trees is decisive. Conclusions Drought risk is a serious issue in the eastern regions independent of the applied silvicultural scenario, but adaptation measures are limited as the proportion of the most drought tolerant species Scots pine is already high. Windthrow risk is no serious overall threat in any region, but adequate

  15. In uncertainty we trust: a median voter model with risk aversion

    Directory of Open Access Journals (Sweden)

    Pavel A. Yakovlev

    2011-12-01

    Full Text Available The principal-agent problem and uncertainty are some of the key factors affecting financial and political markets. Fear of the unknown plays an important role in human decision making, including voting. This article describes a theoretical model where voter risk aversion towards uncertainty gives political incumbents a significant advantage over their challengers, exacerbating the principal-agent problem between voters and legislators. The model presented predicts that a rise in voter uncertainty concerning the challenger allows the incumbent to deviate from the median voter’s policy preference without losing the election. This model reconciles the paradoxical coexistence of ideological shirking and high incumbent reelection rates without abandoning the elegant median voter framework.

  16. Using Statistical and Probabilistic Methods to Evaluate Health Risk Assessment: A Case Study

    Directory of Open Access Journals (Sweden)

    Hongjing Wu

    2014-06-01

    Full Text Available The toxic chemical and heavy metals within wastewater can cause serious adverse impacts on human health. Health risk assessment (HRA is an effective tool for supporting decision-making and corrective actions in water quality management. HRA can also help people understand the water quality and quantify the adverse effects of pollutants on human health. Due to the imprecision of data, measurement error and limited available information, uncertainty is inevitable in the HRA process. The purpose of this study is to integrate statistical and probabilistic methods to deal with censored and limited numbers of input data to improve the reliability of the non-cancer HRA of dermal contact exposure to contaminated river water by considering uncertainty. A case study in the Kelligrews River in St. John’s, Canada, was conducted to demonstrate the feasibility and capacity of the proposed approach. Five heavy metals were selected to evaluate the risk level, including arsenic, molybdenum, zinc, uranium and manganese. The results showed that the probability of the total hazard index of dermal exposure exceeding 1 is very low, and there is no obvious evidence of risk in the study area.

  17. Economics versus psychology.Risk, uncertainty and the expected utility theory

    OpenAIRE

    Schilirò, Daniele

    2017-01-01

    The present contribution examines the emergence of expected utility theory by John von Neumann and Oskar Morgenstern, the subjective the expected utility theory by Savage, and the problem of choice under risk and uncertainty, focusing in particular on the seminal work “The Utility Analysis of Choices involving Risk" (1948) by Milton Friedman and Leonard Savage to show how the evolution of the theory of choice has determined a separation of economics from psychology.

  18. Risco, incerteza e as possibilidades de ação na saúde ambiental Risk, uncertainty and the possibilities of action in environmental health

    Directory of Open Access Journals (Sweden)

    Renato Rocha Lieber

    2003-06-01

    Full Text Available O conceito de risco vem tendo uso crescente no entendimento das relações entre saúde e ambiente. Uma revisão recente do seu emprego¹ mostrou que o risco é próprio da condição humana e que a exclusão da incerteza promove a manutenção do status quo. O problema que se coloca é como propor ações de melhoria na saúde ambiental sob os pressupostos da dúvida e da incerteza que caracterizam a condição de risco. Como proposta de solução, a obra de H. Arendt² prestou-se ao exame dos significados e das implicações da incerteza no campo do pensamento e no campo da ação. Os resultados mostram que o risco se insere na lacuna construída entre o passado e o futuro. Quando esta lacuna passa a ser entendida como espaço de possibilidades, a incerteza, produzida no campo do pensamento fomenta a liberdade e a participação no campo da ação. A valorização da subjetividade e o exercício do juízo promovem a configuração de novos contextos e de novas possibilidades de ação, tanto em relação à natureza como em relação aos homens. Este conhecimento novo se insere na lacuna entre passado e futuro e realimenta o processo. Conclui-se que as ações de "promoção da saúde" devem estar aptas a aceitar resultados não necessariamente idealizados. Na ação livre não existem certezas e a sua relevância não está nos fins que se possa estabelecer, mas no processo do seu exercício.The concept of risk has been increasingly used in the understanding of the relationship between health and environment. A recent review of its use¹ showed that risk belongs to the human condition and that excluding uncertainty promotes maintaining the status quo. The question is how to propose actions to improve environmental health under the assumptions of doubt and uncertainty that characterize the condition of risk. As a proposal for a solution, the work of H. Arendt² examined the meanings and implications of uncertainty in the field of thought and

  19. Principles for decisions involving environmental and health risks

    International Nuclear Information System (INIS)

    Bengtsson, B.

    1989-01-01

    Decision making with respect to safety is becoming more and more complex. The risk involved must be taken into account together with numerous other factors such as the benefits, the uncertainties and the public perception. Can the decision maker be aided by some kind of system, general rules of thumb, or broader perspective on similar decisions? This question has been addressed in a joint Nordic project relating to nuclear power. Modern techniques for risk assessment and management have been studied and parallels drawn to such areas as offshore safety and management of genotoxic chemicals in the environment. The topics include synoptic vs. incrementalistic approaches to decision making, health hazards from radiation and genotoxic chemicals, value judgments in decision making, definitions of low risks, risk comparisons, and principles for decision making when risks are involved. (author) 47 refs

  20. Uncertainty as Knowledge: Constraints on Policy Choices Provided by Analysis of Uncertainty

    Science.gov (United States)

    Lewandowsky, S.; Risbey, J.; Smithson, M.; Newell, B. R.

    2012-12-01

    Uncertainty forms an integral part of climate science, and it is often cited in connection with arguments against mitigative action. We argue that an analysis of uncertainty must consider existing knowledge as well as uncertainty, and the two must be evaluated with respect to the outcomes and risks associated with possible policy options. Although risk judgments are inherently subjective, an analysis of the role of uncertainty within the climate system yields two constraints that are robust to a broad range of assumptions. Those constraints are that (a) greater uncertainty about the climate system is necessarily associated with greater expected damages from warming, and (b) greater uncertainty translates into a greater risk of the failure of mitigation efforts. These ordinal constraints are unaffected by subjective or cultural risk-perception factors, they are independent of the discount rate, and they are independent of the magnitude of the estimate for climate sensitivity. The constraints mean that any appeal to uncertainty must imply a stronger, rather than weaker, need to cut greenhouse gas emissions than in the absence of uncertainty.

  1. Integration of expert knowledge and uncertainty in natural risk assessment

    Science.gov (United States)

    Baruffini, Mirko; Jaboyedoff, Michel

    2010-05-01

    Natural hazards occurring in alpine regions during the last decades have clearly shown that interruptions of the Swiss railway power supply and closures of the Gotthard highway due to those events have increased the awareness of infrastructure vulnerability also in Switzerland and illustrate the potential impacts of failures on the performance of infrastructure systems. This asks for a high level of surveillance and preservation along the transalpine lines. Traditional simulation models are only partially capable to predict complex systems behaviours and the subsequently designed and implemented protection strategies are not able to mitigate the full spectrum of risk consequences. They are costly, and maximal protection is most probably not economically feasible. In addition, the quantitative risk assessment approaches such as fault tree analysis, event tree analysis and equivalent annual fatality analysis rely heavily on statistical information. Collecting sufficient data to base a statistical probability of risk is costly and, in many situations, such data does not exist; thus, expert knowledge and experience or engineering judgment can be exploited to estimate risk qualitatively. In order to overcome the statistics lack we used models based on expert's knowledge in order to qualitatively predict based on linguistic appreciation that are more expressive and natural in risk assessment. Fuzzy reasoning (FR) can be used providing a mechanism of computing with words (Zadeh, 1965) for modelling qualitative human thought processes in analyzing complex systems and decisions. Uncertainty in predicting the risk levels arises from such situations because no fully-formalized knowledge are available. Another possibility is to use probability based on triangular probability density function (T-PDF) that can be used to follow the same flow-chart as FR. We implemented the Swiss natural hazard recommendations FR and probability using T-PDF in order to obtain hazard zoning and

  2. Bayesian Hierarchical Structure for Quantifying Population Variability to Inform Probabilistic Health Risk Assessments.

    Science.gov (United States)

    Shao, Kan; Allen, Bruce C; Wheeler, Matthew W

    2017-10-01

    Human variability is a very important factor considered in human health risk assessment for protecting sensitive populations from chemical exposure. Traditionally, to account for this variability, an interhuman uncertainty factor is applied to lower the exposure limit. However, using a fixed uncertainty factor rather than probabilistically accounting for human variability can hardly support probabilistic risk assessment advocated by a number of researchers; new methods are needed to probabilistically quantify human population variability. We propose a Bayesian hierarchical model to quantify variability among different populations. This approach jointly characterizes the distribution of risk at background exposure and the sensitivity of response to exposure, which are commonly represented by model parameters. We demonstrate, through both an application to real data and a simulation study, that using the proposed hierarchical structure adequately characterizes variability across different populations. © 2016 Society for Risk Analysis.

  3. Trust and truth: uncertainty in health care practice.

    Science.gov (United States)

    Tyreman, Stephen

    2015-06-01

    Uncertainty is the ubiquitous presence across health care. It is usually understood in terms of decision making, 'knowing' the correct diagnosis or understanding how the human body works. Using the work of Ludwig Wittgenstein, Georges Canguilhem and Tim Ingold, I outline a story of journeying and habitation, and argue that while uncertainty for practitioners may be about enhancing theoretical knowledge, for patients it is about knowing how to act in a taken-for-granted and largely unconscious way in a world that has become uncertain, and in which the main tool of action, the human body, no longer functions with the certainty it once had. In this situation, the role of the practitioner is first and foremost to recognize the uncertainty that has emerged in the patient's 'habitation' and to reassure them by enabling them to have a new or restored confidence in their body so that they can act with certainty. © 2015 John Wiley & Sons, Ltd.

  4. Uncertainty and Sensitivity of Direct Economic Flood Damages: the FloodRisk Free and Open-Source Software

    Science.gov (United States)

    Albano, R.; Sole, A.; Mancusi, L.; Cantisani, A.; Perrone, A.

    2017-12-01

    The considerable increase of flood damages in the the past decades has shifted in Europe the attention from protection against floods to managing flood risks. In this context, the expected damages assessment represents a crucial information within the overall flood risk management process. The present paper proposes an open source software, called FloodRisk, that is able to operatively support stakeholders in the decision making processes with a what-if approach by carrying out the rapid assessment of the flood consequences, in terms of direct economic damage and loss of human lives. The evaluation of the damage scenarios, trough the use of the GIS software proposed here, is essential for cost-benefit or multi-criteria analysis of risk mitigation alternatives. However, considering that quantitative assessment of flood damages scenarios is characterized by intrinsic uncertainty, a scheme has been developed to identify and quantify the role of the input parameters in the total uncertainty of flood loss model application in urban areas with mild terrain and complex topography. By the concept of parallel models, the contribution of different module and input parameters to the total uncertainty is quantified. The results of the present case study have exhibited a high epistemic uncertainty on the damage estimation module and, in particular, on the type and form of the utilized damage functions, which have been adapted and transferred from different geographic and socio-economic contexts because there aren't depth-damage functions that are specifically developed for Italy. Considering that uncertainty and sensitivity depend considerably on local characteristics, the epistemic uncertainty associated with the risk estimate is reduced by introducing additional information into the risk analysis. In the light of the obtained results, it is evident the need to produce and disseminate (open) data to develop micro-scale vulnerability curves. Moreover, the urgent need to push

  5. Uncertainty analysis in estimating Japanese ingestion of global fallout Cs-137 using health risk evaluation model

    International Nuclear Information System (INIS)

    Shimada, Yoko; Morisawa, Shinsuke

    1998-01-01

    Most of model estimation of the environmental contamination includes some uncertainty associated with the parameter uncertainty in the model. In this study, the uncertainty was analyzed in a model for evaluating the ingestion of radionuclide caused by the long-term global low-level radioactive contamination by using various uncertainty analysis methods: the percentile estimate, the robustness analysis and the fuzzy estimate. The model is mainly composed of five sub-models, which include their own uncertainty; we also analyzed the uncertainty. The major findings obtained in this study include that the possibility of the discrepancy between predicted value by the model simulation and the observed data is less than 10%; the uncertainty of the predicted value is higher before 1950 and after 1980; the uncertainty of the predicted value can be reduced by decreasing the uncertainty of some environmental parameters in the model; the reliability of the model can definitively depend on the following environmental factors: direct foliar absorption coefficient, transfer factor of radionuclide from stratosphere down to troposphere, residual rate by food processing and cooking, transfer factor of radionuclide in ocean and sedimentation in ocean. (author)

  6. Unquestioned answers or unanswered questions: beliefs about science guide responses to uncertainty in climate change risk communication.

    Science.gov (United States)

    Rabinovich, Anna; Morton, Thomas A

    2012-06-01

    In two experimental studies we investigated the effect of beliefs about the nature and purpose of science (classical vs. Kuhnian models of science) on responses to uncertainty in scientific messages about climate change risk. The results revealed a significant interaction between both measured (Study 1) and manipulated (Study 2) beliefs about science and the level of communicated uncertainty on willingness to act in line with the message. Specifically, messages that communicated high uncertainty were more persuasive for participants who shared an understanding of science as debate than for those who believed that science is a search for absolute truth. In addition, participants who had a concept of science as debate were more motivated by higher (rather than lower) uncertainty in climate change messages. The results suggest that achieving alignment between the general public's beliefs about science and the style of the scientific messages is crucial for successful risk communication in science. Accordingly, rather than uncertainty always undermining the effectiveness of science communication, uncertainty can enhance message effects when it fits the audience's understanding of what science is. © 2012 Society for Risk Analysis.

  7. A risk-averse optimization model for trading wind energy in a market environment under uncertainty

    International Nuclear Information System (INIS)

    Pousinho, H.M.I.; Mendes, V.M.F.; Catalao, J.P.S.

    2011-01-01

    In this paper, a stochastic programming approach is proposed for trading wind energy in a market environment under uncertainty. Uncertainty in the energy market prices is the main cause of high volatility of profits achieved by power producers. The volatile and intermittent nature of wind energy represents another source of uncertainty. Hence, each uncertain parameter is modeled by scenarios, where each scenario represents a plausible realization of the uncertain parameters with an associated occurrence probability. Also, an appropriate risk measurement is considered. The proposed approach is applied on a realistic case study, based on a wind farm in Portugal. Finally, conclusions are duly drawn. -- Highlights: → We model uncertainties on energy market prices and wind power production. → A hybrid intelligent approach generates price-wind power scenarios. → Risk aversion is also incorporated in the proposed stochastic programming approach. → A realistic case study, based on a wind farm in Portugal, is provided. → Our approach allows selecting the best solution according to the desired risk exposure level.

  8. Risk assessment calculations using MEPAS, an accepted screening methodology, and an uncertainty analysis for the reranking of Waste Area Groupings at Oak Ridge National Laboratory, Oak Ridge, Tennessee

    International Nuclear Information System (INIS)

    Shevenell, L.; Hoffman, F.O.; MacIntosh, D.

    1992-03-01

    The Waste Area Groupings (WAGs) at the Oak Ridge National Laboratory (ORNL) were reranked with respect to on- and off-site human health risks using two different methods. Risks associated with selected contaminants from each WAG for occupants of WAG 2 or an off-site area were calculated using a modified formulation of the Multimedia Environmental Pollutant Assessment System (MEPAS) and a method suitable for screening, referred to as the ORNL/ESD method (the method developed by the Environmental Sciences Division at ORNL) in this report. Each method resulted in a different ranking of the WAGs. The rankings from the two methods are compared in this report. All risk assessment calculations, except the original MEPAS calculations, indicated that WAGs 1; 2, 6, 7 (WAGs 2, 6 and 7 as one combined WAG); and 4 pose the greatest potential threat to human health. However, the overall rankings of the WAGs using constant parameter values in the different methods were inconclusive because uncertainty in parameter values can change the calculated risk associated with particular pathways, and hence, the final rankings. Uncertainty analysis using uncertainties about all model parameters were used to reduce biases associated with parameter selection and to more reliably rank waste sites according to potential risks associated with site contaminants. Uncertainty analysis indicates that the WAGs should be considered for further investigation, or remediation, in the following order: (1) WAG 1; (2) WAGs 2, 6, and 7 (combined); and 4; (3) WAGs 3, 5, and 9; and, (4) WAG 8

  9. Uncertainty, causality and decision: The case of social risks and nuclear risk in particular

    International Nuclear Information System (INIS)

    Lahidji, R.

    2012-01-01

    Probability and causality are two indispensable tools for addressing situations of social risk. Causal relations are the foundation for building risk assessment models and identifying risk prevention, mitigation and compensation measures. Probability enables us to quantify risk assessments and to calibrate intervention measures. It therefore seems not only natural, but also necessary to make the role of causality and probability explicit in the definition of decision problems in situations of social risk. Such is the aim of this thesis.By reviewing the terminology of risk and the logic of public interventions in various fields of social risk, we gain a better understanding of the notion and of the issues that one faces when trying to model it. We further elaborate our analysis in the case of nuclear safety, examining in detail how methods and policies have been developed in this field and how they have evolved through time. This leads to a number of observations concerning risk and safety assessments.Generalising the concept of intervention in a Bayesian network allows us to develop a variety of causal Bayesian networks adapted to our needs. In this framework, we propose a definition of risk which seems to be relevant for a broad range of issues. We then offer simple applications of our model to specific aspects of the Fukushima accident and other nuclear safety problems. In addition to specific lessons, the analysis leads to the conclusion that a systematic approach for identifying uncertainties is needed in this area. When applied to decision theory, our tool evolves into a dynamic decision model in which acts cause consequences and are causally interconnected. The model provides a causal interpretation of Savage's conceptual framework, solves some of its paradoxes and clarifies certain aspects. It leads us to considering uncertainty with regard to a problem's causal structure as the source of ambiguity in decision-making, an interpretation which corresponds to a

  10. Risk assessment for improved treatment of health considerations in EIA

    International Nuclear Information System (INIS)

    Demidova, Olga; Cherp, Aleg

    2005-01-01

    Environmental Impact Assessment (EIA) and Risk Assessment (RA) processes are rarely used to complement each other despite potential benefits of such integration. This paper proposes a model for procedural and methodological integration of EIA and RA based on reported best practice approaches. The proposed model stipulates 'embedding' RA into EIA and is organized in accordance with the generic stages of the EIA process. The model forms the basis for the proposed Evaluation Package which can be used as a benchmarking tool for evaluating the effectiveness of integration of RA within particular EIAs. The current paper uses the package for evaluating seven Environmental Impact Statements (EISs) of waste incineration facilities in the UK produced between 1990 and 2000. Though RA was found to be an element of these EIAs, its prominence varied considerably from case to case. Systematic application of RA in accordance with the best practice was not observed. Particular omissions were demonstrated in assessing health impacts not directly associated with air emissions, identifying the receptors of health impacts (affected population), interpreting health impacts as health risks, dealing with uncertainties, and risk communications

  11. Communicating Uncertainty about Climate Change for Application to Security Risk Management

    Science.gov (United States)

    Gulledge, J. M.

    2011-12-01

    The science of climate change has convincingly demonstrated that human activities, including the release of greenhouse gases, land-surface changes, particle emissions, and redistribution of water, are changing global and regional climates. Consequently, key institutions are now concerned about the potential social impacts of climate change. For example, the 2010 Quadrennial Defense Review Report from the U.S. Department of Defense states that "climate change, energy security, and economic stability are inextricably linked." Meanwhile, insured losses from climate and weather-related natural disasters have risen dramatically over the past thirty years. Although these losses stem largely from socioeconomic trends, insurers are concerned that climate change could exacerbate this trend and render certain types of climate risk non-diversifiable. Meanwhile, the climate science community-broadly defined as physical, biological, and social scientists focused on some aspect of climate change-remains largely focused scholarly activities that are valued in the academy but not especially useful to decision makers. On the other hand, climate scientists who engage in policy discussions have generally permitted vested interests who support or oppose climate policies to frame the discussion of climate science within the policy arena. Such discussions focus on whether scientific uncertainties are sufficiently resolved to justify policy and the vested interests overstate or understate key uncertainties to support their own agendas. Consequently, the scientific community has become absorbed defending scientific findings to the near exclusion of developing novel tools to aid in risk-based decision-making. For example, the Intergovernmental Panel on Climate Change (IPCC), established expressly for the purpose of informing governments, has largely been engaged in attempts to reduce unavoidable uncertainties rather than helping the world's governments define a science-based risk

  12. Risk estimation and decision making: the health effects on populations of exposure to low levels of ionizing radiation

    International Nuclear Information System (INIS)

    Fabrikant, J.I.

    1982-01-01

    Presented is a background for an understanding of the potential health effects in populations exposed to low-level radiation. Discussed is the knowledge about the health effects of low-level radiation. Comments on how the risks of radiation-induced cancer and genetically-related ill-health in man may be estimated, the sources of the scientific and epidemiological data, the dose-response models used, and the uncertainties which limit precise estimates of excess risks from radiation. Also discussed are the implications of numerical risk estimation for radiation protection and decision-making for public health policy

  13. Ignoring correlation in uncertainty and sensitivity analysis in life cycle assessment: what is the risk?

    Energy Technology Data Exchange (ETDEWEB)

    Groen, E.A., E-mail: Evelyne.Groen@gmail.com [Wageningen University, P.O. Box 338, Wageningen 6700 AH (Netherlands); Heijungs, R. [Vrije Universiteit Amsterdam, De Boelelaan 1105, Amsterdam 1081 HV (Netherlands); Leiden University, Einsteinweg 2, Leiden 2333 CC (Netherlands)

    2017-01-15

    Life cycle assessment (LCA) is an established tool to quantify the environmental impact of a product. A good assessment of uncertainty is important for making well-informed decisions in comparative LCA, as well as for correctly prioritising data collection efforts. Under- or overestimation of output uncertainty (e.g. output variance) will lead to incorrect decisions in such matters. The presence of correlations between input parameters during uncertainty propagation, can increase or decrease the the output variance. However, most LCA studies that include uncertainty analysis, ignore correlations between input parameters during uncertainty propagation, which may lead to incorrect conclusions. Two approaches to include correlations between input parameters during uncertainty propagation and global sensitivity analysis were studied: an analytical approach and a sampling approach. The use of both approaches is illustrated for an artificial case study of electricity production. Results demonstrate that both approaches yield approximately the same output variance and sensitivity indices for this specific case study. Furthermore, we demonstrate that the analytical approach can be used to quantify the risk of ignoring correlations between input parameters during uncertainty propagation in LCA. We demonstrate that: (1) we can predict if including correlations among input parameters in uncertainty propagation will increase or decrease output variance; (2) we can quantify the risk of ignoring correlations on the output variance and the global sensitivity indices. Moreover, this procedure requires only little data. - Highlights: • Ignoring correlation leads to under- or overestimation of the output variance. • We demonstrated that the risk of ignoring correlation can be quantified. • The procedure proposed is generally applicable in life cycle assessment. • In some cases, ignoring correlation has a minimal effect on decision-making tools.

  14. Uncertainty and Risk Management in Cyber Situational Awareness

    Science.gov (United States)

    Li, Jason; Ou, Xinming; Rajagopalan, Raj

    Handling cyber threats unavoidably needs to deal with both uncertain and imprecise information. What we can observe as potential malicious activities can seldom give us 100% confidence on important questions we care about, e.g. what machines are compromised and what damage has been incurred. In security planning, we need information on how likely a vulnerability can lead to a successful compromise to better balance security and functionality, performance, and ease of use. These information are at best qualitative and are often vague and imprecise. In cyber situational awareness, we have to rely on such imperfect information to detect real attacks and to prevent an attack from happening through appropriate risk management. This chapter surveys existing technologies in handling uncertainty and risk management in cyber situational awareness.

  15. Climate uncertainty and implications for U.S. state-level risk assessment through 2050.

    Energy Technology Data Exchange (ETDEWEB)

    Loose, Verne W.; Lowry, Thomas Stephen; Malczynski, Leonard A.; Tidwell, Vincent Carroll; Stamber, Kevin Louis; Kelic, Andjelka; Backus, George A.; Warren, Drake E.; Zagonel, Aldo A.; Ehlen, Mark Andrew; Klise, Geoffrey T.; Vargas, Vanessa N.

    2009-10-01

    Decisions for climate policy will need to take place in advance of climate science resolving all relevant uncertainties. Further, if the concern of policy is to reduce risk, then the best-estimate of climate change impacts may not be so important as the currently understood uncertainty associated with realizable conditions having high consequence. This study focuses on one of the most uncertain aspects of future climate change - precipitation - to understand the implications of uncertainty on risk and the near-term justification for interventions to mitigate the course of climate change. We show that the mean risk of damage to the economy from climate change, at the national level, is on the order of one trillion dollars over the next 40 years, with employment impacts of nearly 7 million labor-years. At a 1% exceedance-probability, the impact is over twice the mean-risk value. Impacts at the level of individual U.S. states are then typically in the multiple tens of billions dollar range with employment losses exceeding hundreds of thousands of labor-years. We used results of the Intergovernmental Panel on Climate Change's (IPCC) Fourth Assessment Report 4 (AR4) climate-model ensemble as the referent for climate uncertainty over the next 40 years, mapped the simulated weather hydrologically to the county level for determining the physical consequence to economic activity at the state level, and then performed a detailed, seventy-industry, analysis of economic impact among the interacting lower-48 states. We determined industry GDP and employment impacts at the state level, as well as interstate population migration, effect on personal income, and the consequences for the U.S. trade balance.

  16. Sensitivity of Asteroid Impact Risk to Uncertainty in Asteroid Properties and Entry Parameters

    Science.gov (United States)

    Wheeler, Lorien; Mathias, Donovan; Dotson, Jessie L.; NASA Asteroid Threat Assessment Project

    2017-10-01

    A central challenge in assessing the threat posed by asteroids striking Earth is the large amount of uncertainty inherent throughout all aspects of the problem. Many asteroid properties are not well characterized and can range widely from strong, dense, monolithic irons to loosely bound, highly porous rubble piles. Even for an object of known properties, the specific entry velocity, angle, and impact location can swing the potential consequence from no damage to causing millions of casualties. Due to the extreme rarity of large asteroid strikes, there are also large uncertainties in how different types of asteroids will interact with the atmosphere during entry, how readily they may break up or ablate, and how much surface damage will be caused by the resulting airbursts or impacts.In this work, we use our Probabilistic Asteroid Impact Risk (PAIR) model to investigate the sensitivity of asteroid impact damage to uncertainties in key asteroid properties, entry parameters, or modeling assumptions. The PAIR model combines physics-based analytic models of asteroid entry and damage in a probabilistic Monte Carlo framework to assess the risk posed by a wide range of potential impacts. The model samples from uncertainty distributions of asteroid properties and entry parameters to generate millions of specific impact cases, and models the atmospheric entry and damage for each case, including blast overpressure, thermal radiation, tsunami inundation, and global effects. To assess the risk sensitivity, we alternately fix and vary the different input parameters and compare the effect on the resulting range of damage produced. The goal of these studies is to help guide future efforts in asteroid characterization and model refinement by determining which properties most significantly affect the potential risk.

  17. The shape of uncertainty: underwriting decisions in the face of catastrophic risk

    International Nuclear Information System (INIS)

    Keykhah, M.

    1998-01-01

    This paper will explore how insurance and re-insurance underwriters price catastrophe risk from natural perils. It will first describe the theoretical nature of pricing risk, and outline studies of underwriting that propose analyzing decision making from a more behavioral than rational choice perspective. The paper then argues that in order to provide the appropriate context for probability (which is the focus of the studies on decision making under uncertainty), it may be helpful to look at the nature of choice within a market and organizational context. Moreover, the nature of probability itself is explored with a review to construct a broader analysis. Finally, it will be argued that the causal framework of the underwriter, in addition to inductive reasoning, provides a shape to uncertainty. (author)

  18. Visualizing the uncertainty in the relationship between seasonal average climate and malaria risk.

    Science.gov (United States)

    MacLeod, D A; Morse, A P

    2014-12-02

    Around $1.6 billion per year is spent financing anti-malaria initiatives, and though malaria morbidity is falling, the impact of annual epidemics remains significant. Whilst malaria risk may increase with climate change, projections are highly uncertain and to sidestep this intractable uncertainty, adaptation efforts should improve societal ability to anticipate and mitigate individual events. Anticipation of climate-related events is made possible by seasonal climate forecasting, from which warnings of anomalous seasonal average temperature and rainfall, months in advance are possible. Seasonal climate hindcasts have been used to drive climate-based models for malaria, showing significant skill for observed malaria incidence. However, the relationship between seasonal average climate and malaria risk remains unquantified. Here we explore this relationship, using a dynamic weather-driven malaria model. We also quantify key uncertainty in the malaria model, by introducing variability in one of the first order uncertainties in model formulation. Results are visualized as location-specific impact surfaces: easily integrated with ensemble seasonal climate forecasts, and intuitively communicating quantified uncertainty. Methods are demonstrated for two epidemic regions, and are not limited to malaria modeling; the visualization method could be applied to any climate impact.

  19. Uncertainty Analysis and Overtopping Risk Evaluation of Maroon Dam withMonte Carlo and Latin Hypercube Methods

    Directory of Open Access Journals (Sweden)

    J. M. Vali Samani

    2016-02-01

    Full Text Available Introduction: The greatest part of constructed dams belongs to embankment dams and there are many examples of their failures throughout history. About one-third of the world’s dam failures have been caused by flood overtopping, which indicates that flood overtopping is an important factor affecting reservoir projects’ safety. Moreover, because of a poor understanding of the randomness of floods, reservoir water levels during flood seasons are often lowered artificially in order to avoid overtopping and protect the lives and property of downstream residents. So, estimation of dam overtopping risk with regard to uncertainties is more important than achieving the dam’s safety. This study presents the procedure for risk evaluation of dam overtopping due to various uncertaintiess in inflows and reservoir initial condition. Materials and Methods: This study aims to present a practical approach and compare the different uncertainty analysis methods in the evaluation of dam overtopping risk due to flood. For this purpose, Monte Carlo simulation and Latin hypercube sampling methods were used to calculate the overtopping risk, evaluate the uncertainty, and calculate the highest water level during different flood events. To assess these methods from a practical point of view, the Maroon dam was chosen for the case study. Figure. 1 indicates the work procedure, including three parts: 1 Identification and evaluation of effective factors on flood routing and dam overtopping, 2 Data collection and analysis for reservoir routing and uncertainty analysis, 3 Uncertainty and risk analysis. Figure 1- Diagram of dam overtopping risk evaluation Results and Discussion: Figure 2 shows the results of the computed overtopping risks for the Maroon Dam without considering the wind effect, for the initial water level of 504 m as an example. As it is shown in Figure. 2, the trends of the risk curves computed by the different uncertainty analysis methods are similar

  20. Oral-to-inhalation route extrapolation in occupational health risk assessment: A critical assessment

    NARCIS (Netherlands)

    Rennen, M.A.J.; Bouwman, T.; Wilschut, A.; Bessems, J.G.M.; Heer, C.de

    2004-01-01

    Due to a lack of route-specific toxicity data, the health risks resulting from occupational exposure are frequently assessed by route-to-route (RtR) extrapolation based on oral toxicity data. Insight into the conditions for and the uncertainties connected with the application of RtR extrapolation

  1. Impacts of representing sea-level rise uncertainty on future flood risks: An example from San Francisco Bay.

    Science.gov (United States)

    Ruckert, Kelsey L; Oddo, Perry C; Keller, Klaus

    2017-01-01

    Rising sea levels increase the probability of future coastal flooding. Many decision-makers use risk analyses to inform the design of sea-level rise (SLR) adaptation strategies. These analyses are often silent on potentially relevant uncertainties. For example, some previous risk analyses use the expected, best, or large quantile (i.e., 90%) estimate of future SLR. Here, we use a case study to quantify and illustrate how neglecting SLR uncertainties can bias risk projections. Specifically, we focus on the future 100-yr (1% annual exceedance probability) coastal flood height (storm surge including SLR) in the year 2100 in the San Francisco Bay area. We find that accounting for uncertainty in future SLR increases the return level (the height associated with a probability of occurrence) by half a meter from roughly 2.2 to 2.7 m, compared to using the mean sea-level projection. Accounting for this uncertainty also changes the shape of the relationship between the return period (the inverse probability that an event of interest will occur) and the return level. For instance, incorporating uncertainties shortens the return period associated with the 2.2 m return level from a 100-yr to roughly a 7-yr return period (∼15% probability). Additionally, accounting for this uncertainty doubles the area at risk of flooding (the area to be flooded under a certain height; e.g., the 100-yr flood height) in San Francisco. These results indicate that the method of accounting for future SLR can have considerable impacts on the design of flood risk management strategies.

  2. Impacts of representing sea-level rise uncertainty on future flood risks: An example from San Francisco Bay.

    Directory of Open Access Journals (Sweden)

    Kelsey L Ruckert

    Full Text Available Rising sea levels increase the probability of future coastal flooding. Many decision-makers use risk analyses to inform the design of sea-level rise (SLR adaptation strategies. These analyses are often silent on potentially relevant uncertainties. For example, some previous risk analyses use the expected, best, or large quantile (i.e., 90% estimate of future SLR. Here, we use a case study to quantify and illustrate how neglecting SLR uncertainties can bias risk projections. Specifically, we focus on the future 100-yr (1% annual exceedance probability coastal flood height (storm surge including SLR in the year 2100 in the San Francisco Bay area. We find that accounting for uncertainty in future SLR increases the return level (the height associated with a probability of occurrence by half a meter from roughly 2.2 to 2.7 m, compared to using the mean sea-level projection. Accounting for this uncertainty also changes the shape of the relationship between the return period (the inverse probability that an event of interest will occur and the return level. For instance, incorporating uncertainties shortens the return period associated with the 2.2 m return level from a 100-yr to roughly a 7-yr return period (∼15% probability. Additionally, accounting for this uncertainty doubles the area at risk of flooding (the area to be flooded under a certain height; e.g., the 100-yr flood height in San Francisco. These results indicate that the method of accounting for future SLR can have considerable impacts on the design of flood risk management strategies.

  3. Rethinking Risk: Prospect Theory Application in Health Message Framing Research.

    Science.gov (United States)

    Harrington, Nancy Grant; Kerr, Anna M

    2017-02-01

    Although prospect theory conceptualizes risk as uncertainty, health message framing research based on the theory typically conceptualizes risk as severity. This study reports the results of two experiments designed to explore these alternative conceptualizations of risk and their effect on health decision making. Participants (N 1  = 768, N 2  = 532) were randomly assigned to one of four conditions that presented a hypothetical scenario of a sexually transmitted disease (STD) outbreak. The conditions were defined by message prompt (deadly vs. easily curable STD) and response option frame (gain vs. loss). Participants selected which of two programs (certain outcome vs. uncertain outcome) they would prefer to combat the outbreak. Across both experiments, participants expressed strong preferences for certain (low risk) outcomes in the gain-framed conditions and no preferences in the loss-framed conditions. These differences held regardless of the consequence severity of the scenario. We discuss the theoretical and practical implications of these results and offer directions for future research.

  4. The HTA Risk Analysis Chart: Visualising the Need for and Potential Value of Managed Entry Agreements in Health Technology Assessment.

    Science.gov (United States)

    Grimm, Sabine Elisabeth; Strong, Mark; Brennan, Alan; Wailoo, Allan J

    2017-12-01

    Recent changes to the regulatory landscape of pharmaceuticals may sometimes require reimbursement authorities to issue guidance on technologies that have a less mature evidence base. Decision makers need to be aware of risks associated with such health technology assessment (HTA) decisions and the potential to manage this risk through managed entry agreements (MEAs). This work develops methods for quantifying risk associated with specific MEAs and for clearly communicating this to decision makers. We develop the 'HTA risk analysis chart', in which we present the payer strategy and uncertainty burden (P-SUB) as a measure of overall risk. The P-SUB consists of the payer uncertainty burden (PUB), the risk stemming from decision uncertainty as to which is the truly optimal technology from the relevant set of technologies, and the payer strategy burden (PSB), the additional risk of approving a technology that is not expected to be optimal. We demonstrate the approach using three recent technology appraisals from the UK National Institute for Health and Clinical Excellence (NICE), each of which considered a price-based MEA. The HTA risk analysis chart was calculated using results from standard probabilistic sensitivity analyses. In all three HTAs, the new interventions were associated with substantial risk as measured by the P-SUB. For one of these technologies, the P-SUB was reduced to zero with the proposed price reduction, making this intervention cost effective with near complete certainty. For the other two, the risk reduced substantially with a much reduced PSB and a slightly increased PUB. The HTA risk analysis chart shows the risk that the healthcare payer incurs under unresolved decision uncertainty and when considering recommending a technology that is not expected to be optimal given current evidence. This allows the simultaneous consideration of financial and data-collection MEA schemes in an easily understood format. The use of HTA risk analysis charts will

  5. Health information seeking and the World Wide Web: an uncertainty management perspective.

    Science.gov (United States)

    Rains, Stephen A

    2014-01-01

    Uncertainty management theory was applied in the present study to offer one theoretical explanation for how individuals use the World Wide Web to acquire health information and to help better understand the implications of the Web for information seeking. The diversity of information sources available on the Web and potential to exert some control over the depth and breadth of one's information-acquisition effort is argued to facilitate uncertainty management. A total of 538 respondents completed a questionnaire about their uncertainty related to cancer prevention and information-seeking behavior. Consistent with study predictions, use of the Web for information seeking interacted with respondents' desired level of uncertainty to predict their actual level of uncertainty about cancer prevention. The results offer evidence that respondents who used the Web to search for cancer information were better able than were respondents who did not seek information to achieve a level of uncertainty commensurate with the level of uncertainty they desired.

  6. Residential building codes, affordability, and health protection: a risk-tradeoff approach.

    Science.gov (United States)

    Hammitt, J K; Belsky, E S; Levy, J I; Graham, J D

    1999-12-01

    Residential building codes intended to promote health and safety may produce unintended countervailing risks by adding to the cost of construction. Higher construction costs increase the price of new homes and may increase health and safety risks through "income" and "stock" effects. The income effect arises because households that purchase a new home have less income remaining for spending on other goods that contribute to health and safety. The stock effect arises because suppression of new-home construction leads to slower replacement of less safe housing units. These countervailing risks are not presently considered in code debates. We demonstrate the feasibility of estimating the approximate magnitude of countervailing risks by combining the income effect with three relatively well understood and significant home-health risks. We estimate that a code change that increases the nationwide cost of constructing and maintaining homes by $150 (0.1% of the average cost to build a single-family home) would induce offsetting risks yielding between 2 and 60 premature fatalities or, including morbidity effects, between 20 and 800 lost quality-adjusted life years (both discounted at 3%) each year the code provision remains in effect. To provide a net health benefit, the code change would need to reduce risk by at least this amount. Future research should refine these estimates, incorporate quantitative uncertainty analysis, and apply a full risk-tradeoff approach to real-world case studies of proposed code changes.

  7. A risk-based method for planning of bus–subway corridor evacuation under hybrid uncertainties

    International Nuclear Information System (INIS)

    Lv, Y.; Yan, X.D.; Sun, W.; Gao, Z.Y.

    2015-01-01

    Emergencies involved in a bus–subway corridor system are associated with many processes and factors with social and economic implications. These processes and factors and their interactions are related to a variety of uncertainties. In this study, an interval chance-constrained integer programming (EICI) method is developed in response to such challenges for bus–subway corridor based evacuation planning. The method couples a chance-constrained programming with an interval integer programming model framework. It can thus deal with interval uncertainties that cannot be quantified with specified probability distribution functions. Meanwhile, it can also reflect stochastic features of traffic flow capacity, and thereby help examine the related violation risk of constraint. The EICI method is applied to a subway incident based evacuation case study. It is solved through an interactive algorithm that does not lead to more complicated intermediate submodels and has a relatively low computational requirement. A number of decision alternatives could be directly generated based on results from the EICI method. It is indicated that the solutions cannot only help decision makers identify desired population evacuation and vehicle dispatch schemes under hybrid uncertainties, but also provide bases for in-depth analyses of tradeoffs among evacuation plans, total evacuation time, and constraint-violation risks. - Highlights: • An inexact model is developed for the bus–subway corridor evacuation management. • It tackles stochastic and interval uncertainties in an integer programming problem. • It can examine violation risk of the roadway flow capacity related constraint. • It will help identify evacuation schemes under hybrid uncertainties

  8. Are Polish firms risk-averting or risk-loving? : evidence on demand uncertainty and the capital-labour ratio in a transition economy

    NARCIS (Netherlands)

    Lensink, Robert; Murinde, Victor; Green, Christopher J.

    1999-01-01

    This paper investigates the effect of demand uncertainty on the capital-labour ratio of non-financial firms in Poland in order to infer the firms’ risk behaviour. A generic model is used to characterise a utility maximising firm in a transition economy with demand uncertainty and imperfect

  9. Risk, Uncertainty and Precaution in Science: The Threshold of the Toxicological Concern Approach in Food Toxicology.

    Science.gov (United States)

    Bschir, Karim

    2017-04-01

    Environmental risk assessment is often affected by severe uncertainty. The frequently invoked precautionary principle helps to guide risk assessment and decision-making in the face of scientific uncertainty. In many contexts, however, uncertainties play a role not only in the application of scientific models but also in their development. Building on recent literature in the philosophy of science, this paper argues that precaution should be exercised at the stage when tools for risk assessment are developed as well as when they are used to inform decision-making. The relevance and consequences of this claim are discussed in the context of the threshold of the toxicological concern approach in food toxicology. I conclude that the approach does not meet the standards of an epistemic version of the precautionary principle.

  10. Strategy for prioritizing whistleblowing with potential risks related to health services

    Directory of Open Access Journals (Sweden)

    Rafael Fernandes Barros

    2017-11-01

    Full Text Available Introduction: The Sanitary Surveillance of Health Services receives daily denunciations that refer to situations of risk that can hardly be measured quantitatively and attribute to some type of specific damage, in a context of great uncertainty. Objective: Considering such situations should be adequately addressed under the health risk paradigm, this work had as objective identifying notions about risk and its forms of analysis in the scope of Sanitary Surveillance of Health Services, as well as the existence of strategies and models in the analysis and treatment of denunciations. Method: An extensive literature review (through the Regional Portal of the BVS, databases SciELO and SciELO Books, and the journal Visa em Debate was conducted. Results: Although the results point to a relatively recent discussion regarding the model of potential risk analysis as an operational concept for the field of health surveillance in health services, there is no description of strategies or models applied to the analysis or treatment of whistleblowing. Thus, it is discussed and proposed a strategy for the initial analysis of reports with potential risk, which seeks to bring minimally objective criteria, in a field marked by enormous subjectivity. Conclusions: We conclude by indicating that the presented strategy is an initial instrument for the management of whistleblowing that must be discussed and adapted to the reality and context of health surveillance agencies.

  11. A new perspective on human health risk assessment: Development of a time dependent methodology and the effect of varying exposure durations

    International Nuclear Information System (INIS)

    Siirila, Erica R.; Maxwell, Reed M.

    2012-01-01

    We present a new Time Dependent Risk Assessment (TDRA) that stochastically considers how joint uncertainty and inter-individual variability (JUV) associated with human health risk change as a function of time. In contrast to traditional, time independent assessments of risk, this new formulation relays information on when the risk occurs, how long the duration of risk is, and how risk changes with time. Because the true exposure duration (ED) is often uncertain in a risk assessment, we also investigate how varying the magnitude of fixed size durations (ranging between 5 and 70 years) of this parameter affects the distribution of risk in both the time independent and dependent methodologies. To illustrate this new formulation and to investigate these mechanisms for sensitivity, an example of arsenic contaminated groundwater is used in conjunction with two scenarios of different environmental concentration signals resulting from rate dependencies in geochemical reactions. Cancer risk is computed and compared using environmental concentration ensembles modeled with sorption as 1) a linear equilibrium assumption (LEA) and 2) first order kinetics (Kin). Results show that the information attained in the new time dependent methodology reveals how the uncertainty in other time-dependent processes in the risk assessment may influence the uncertainty in risk. We also show that individual susceptibility also affects how risk changes in time, information that would otherwise be lost in the traditional, time independent methodology. These results are especially pertinent for forecasting risk in time, and for risk managers who are assessing the uncertainty of risk. - Highlights: ► A human health, Time Dependent Risk Assessment (TDRA) methodology is presented. ► TDRA relays information on the magnitude, duration, and fluxes of risk in time. ► Kinetic and equilibrium concentration signals show sensitivity in TDRA results. ► In the TDRA results, individual susceptibility

  12. A new perspective on human health risk assessment: Development of a time dependent methodology and the effect of varying exposure durations

    Energy Technology Data Exchange (ETDEWEB)

    Siirila, Erica R., E-mail: esiirila@mymail.mines.edu [Hydrologic Science and Engineering Program, Colorado School of Mines, 1500 Illinois St., Golden, CO 80401 (United States); Department of Geology and Geological Engineering, Colorado School of Mines, 1500 Illinois St., Golden, CO 80401 (United States); Maxwell, Reed M., E-mail: rmaxwell@mines.edu [Hydrologic Science and Engineering Program, Colorado School of Mines, 1500 Illinois St., Golden, CO 80401 (United States); Integrated Groundwater Modeling Center (IGWMC), Colorado School of Mines, 1500 Illinois St., Golden, CO 80401 (United States); Department of Geology and Geological Engineering, Colorado School of Mines, 1500 Illinois St., Golden, CO 80401 (United States)

    2012-08-01

    We present a new Time Dependent Risk Assessment (TDRA) that stochastically considers how joint uncertainty and inter-individual variability (JUV) associated with human health risk change as a function of time. In contrast to traditional, time independent assessments of risk, this new formulation relays information on when the risk occurs, how long the duration of risk is, and how risk changes with time. Because the true exposure duration (ED) is often uncertain in a risk assessment, we also investigate how varying the magnitude of fixed size durations (ranging between 5 and 70 years) of this parameter affects the distribution of risk in both the time independent and dependent methodologies. To illustrate this new formulation and to investigate these mechanisms for sensitivity, an example of arsenic contaminated groundwater is used in conjunction with two scenarios of different environmental concentration signals resulting from rate dependencies in geochemical reactions. Cancer risk is computed and compared using environmental concentration ensembles modeled with sorption as 1) a linear equilibrium assumption (LEA) and 2) first order kinetics (Kin). Results show that the information attained in the new time dependent methodology reveals how the uncertainty in other time-dependent processes in the risk assessment may influence the uncertainty in risk. We also show that individual susceptibility also affects how risk changes in time, information that would otherwise be lost in the traditional, time independent methodology. These results are especially pertinent for forecasting risk in time, and for risk managers who are assessing the uncertainty of risk. - Highlights: Black-Right-Pointing-Pointer A human health, Time Dependent Risk Assessment (TDRA) methodology is presented. Black-Right-Pointing-Pointer TDRA relays information on the magnitude, duration, and fluxes of risk in time. Black-Right-Pointing-Pointer Kinetic and equilibrium concentration signals show

  13. Bridging the gap between academic research and regulatory health risk assessment of Endocrine Disrupting Chemicals.

    Science.gov (United States)

    Beronius, Anna; Hanberg, Annika; Zilliacus, Johanna; Rudén, Christina

    2014-12-01

    Regulatory risk assessment is traditionally based primarily on toxicity studies conducted according to standardized and internationally validated test guidelines. However, health risk assessment of endocrine disrupting chemicals (EDCs) is argued to rely on the efficient integration of findings from academic research. The aim of this review was to provide an overview of current developments to facilitate the use of academic research in regulatory risk assessment of chemicals and how certain aspects of study design and reporting are particularly important for the risk assessment process. By bridging the gap between academic research and regulatory health risk assessment of EDCs, scientific uncertainty in risk assessment conclusions can be reduced, allowing for better targeted policy decisions for chemical risk reduction. Copyright © 2014. Published by Elsevier Ltd.

  14. An inexact mixed risk-aversion two-stage stochastic programming model for water resources management under uncertainty.

    Science.gov (United States)

    Li, W; Wang, B; Xie, Y L; Huang, G H; Liu, L

    2015-02-01

    Uncertainties exist in the water resources system, while traditional two-stage stochastic programming is risk-neutral and compares the random variables (e.g., total benefit) to identify the best decisions. To deal with the risk issues, a risk-aversion inexact two-stage stochastic programming model is developed for water resources management under uncertainty. The model was a hybrid methodology of interval-parameter programming, conditional value-at-risk measure, and a general two-stage stochastic programming framework. The method extends on the traditional two-stage stochastic programming method by enabling uncertainties presented as probability density functions and discrete intervals to be effectively incorporated within the optimization framework. It could not only provide information on the benefits of the allocation plan to the decision makers but also measure the extreme expected loss on the second-stage penalty cost. The developed model was applied to a hypothetical case of water resources management. Results showed that that could help managers generate feasible and balanced risk-aversion allocation plans, and analyze the trade-offs between system stability and economy.

  15. Uncertainty Quantification in the Reliability and Risk Assessment of Generation IV Reactors: Final Scientific/Technical Report

    International Nuclear Information System (INIS)

    Vierow, Karen; Aldemir, Tunc

    2009-01-01

    The project entitled, 'Uncertainty Quantification in the Reliability and Risk Assessment of Generation IV Reactors', was conducted as a DOE NERI project collaboration between Texas A and M University and The Ohio State University between March 2006 and June 2009. The overall goal of the proposed project was to develop practical approaches and tools by which dynamic reliability and risk assessment techniques can be used to augment the uncertainty quantification process in probabilistic risk assessment (PRA) methods and PRA applications for Generation IV reactors. This report is the Final Scientific/Technical Report summarizing the project.

  16. Uncertainty Quantification in the Reliability and Risk Assessment of Generation IV Reactors: Final Scientific/Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Vierow, Karen; Aldemir, Tunc

    2009-09-10

    The project entitled, “Uncertainty Quantification in the Reliability and Risk Assessment of Generation IV Reactors”, was conducted as a DOE NERI project collaboration between Texas A&M University and The Ohio State University between March 2006 and June 2009. The overall goal of the proposed project was to develop practical approaches and tools by which dynamic reliability and risk assessment techniques can be used to augment the uncertainty quantification process in probabilistic risk assessment (PRA) methods and PRA applications for Generation IV reactors. This report is the Final Scientific/Technical Report summarizing the project.

  17. Demonstration uncertainty/sensitivity analysis using the health and economic consequence model CRAC2

    International Nuclear Information System (INIS)

    Alpert, D.J.; Iman, R.L.; Johnson, J.D.; Helton, J.C.

    1985-01-01

    This paper summarizes a demonstration uncertainty/sensitivity analysis performed on the reactor accident consequence model CRAC2. The study was performed with uncertainty/sensitivity analysis techniques compiled as part of the MELCOR program. The principal objectives of the study were: 1) to demonstrate the use of the uncertainty/sensitivity analysis techniques on a health and economic consequence model, 2) to test the computer models which implement the techniques, 3) to identify possible difficulties in performing such an analysis, and 4) to explore alternative means of analyzing, displaying, and describing the results. Demonstration of the applicability of the techniques was the motivation for performing this study; thus, the results should not be taken as a definitive uncertainty analysis of health and economic consequences. Nevertheless, significant insights on health and economic consequence analysis can be drawn from the results of this type of study. Latin hypercube sampling (LHS), a modified Monte Carlo technique, was used in this study. LHS generates a multivariate input structure in which all the variables of interest are varied simultaneously and desired correlations between variables are preserved. LHS has been shown to produce estimates of output distribution functions that are comparable with results of larger random samples

  18. Optimal hydro scheduling and offering strategies considering price uncertainty and risk management

    International Nuclear Information System (INIS)

    Catalão, J.P.S.; Pousinho, H.M.I.; Contreras, J.

    2012-01-01

    Hydro energy represents a priority in the energy policy of Portugal, with the aim of decreasing the dependence on fossil fuels. In this context, optimal hydro scheduling acquires added significance in moving towards a sustainable environment. A mixed-integer nonlinear programming approach is considered to enable optimal hydro scheduling for the short-term time horizon, including the effect of head on power production, start-up costs related to the units, multiple regions of operation, and constraints on discharge variation. As new contributions to the field, market uncertainty is introduced in the model via price scenarios and risk management is included using Conditional Value-at-Risk to limit profit volatility. Moreover, plant scheduling and pool offering by the hydro power producer are simultaneously considered to solve a realistic cascaded hydro system. -- Highlights: ► A mixed-integer nonlinear programming approach is considered for optimal hydro scheduling. ► Market uncertainty is introduced in the model via price scenarios. ► Risk management is included using conditional value-at-risk. ► Plant scheduling and pool offering by the hydro power producer are simultaneously considered. ► A realistic cascaded hydro system is solved.

  19. Scientific uncertainties and climate risks

    International Nuclear Information System (INIS)

    Petit, M.

    2005-01-01

    Human activities have induced a significant change in the Earth's atmospheric composition and, most likely, this trend will increase throughout the coming decades. During the last decades, the mean temperature has actually increased by the expected amount. Moreover, the geographical distribution of the warming, and day-to-night temperature variation have evolved as predicted. The magnitude of those changes is relatively small for the time being, but is expected to increase alarmingly during the coming decades. Greenhouse warming is a representative example of the problems of sustainable development: long-term risks can be estimated on a rational basis from scientific laws alone, but the non-specialist is generally not prepared to understand the steps required. However, even the non-specialist has obviously the right to decide about his way of life and the inheritance that he would like to leave for his children, but it is preferable that he is fully informed before making his decisions. Dialog, mutual understanding and confidence must prevail between Science and Society to avoid irrational actions. Controversy among experts is quite frequent. In the case of greenhouse warming, a commendable collective expertise has drastically reduced possible confusion. The Intergovernmental Panel on Climate Change was created jointly by the World Meteorology Organization (WMO) and the UN Program for the Environment (UNEP). Its reports evaluate the state of knowledge on past and future global climate changes, their impact, and the possibility of controlling anthropogenic emissions. The main targeted readers are, nevertheless, non-specialists, who should be made aware of results deduced from approaches that they may not be able to follow step by step. Moreover, these results, in particular, future projections, are, and will remain, subject to some uncertainty, which a fair description of the state of knowledge must include. Many misunderstandings between writers and readers can

  20. Risk management frameworks for human health and environmental risks.

    Science.gov (United States)

    Jardine, Cindy; Hrudey, Steve; Shortreed, John; Craig, Lorraine; Krewski, Daniel; Furgal, Chris; McColl, Stephen

    2003-01-01

    A comprehensive analytical review of the risk assessment, risk management, and risk communication approaches currently being undertaken by key national, provincial/state, territorial, and international agencies was conducted. The information acquired for review was used to identify the differences, commonalities, strengths, and weaknesses among the various approaches, and to identify elements that should be included in an effective, current, and comprehensive approach applicable to environmental, human health and occupational health risks. More than 80 agencies, organizations, and advisory councils, encompassing more than 100 risk documents, were examined during the period from February 2000 until November 2002. An overview was made of the most important general frameworks for risk assessment, risk management, and risk communication for human health and ecological risk, and for occupational health risk. In addition, frameworks for specific applications were reviewed and summarized, including those for (1)contaminated sites; (2) northern contaminants; (3) priority substances; (4) standards development; (5) food safety; (6) medical devices; (7) prescription drug use; (8) emergency response; (9) transportation; (10) risk communication. Twelve frameworks were selected for more extensive review on the basis of representation of the areas of human health, ecological, and occupational health risk; relevance to Canadian risk management needs; representation of comprehensive and well-defined approaches; generalizability with their risk areas; representation of "state of the art" in Canada, the United States, and/or internationally; and extent of usage of potential usage within Canada. These 12 frameworks were: 1. Framework for Environmental Health Risk Management (US Presidential/Congressional Commission on Risk Assessment and Risk Management, 1997). 2. Health Risk Determination: The Challenge of Health Protection (Health and Welfare Canada, 1990). 3. Health Canada Decision

  1. Methodology evaluation of innovative projects under risk and uncertainty

    Directory of Open Access Journals (Sweden)

    2012-09-01

    Full Text Available This article deals with problems connected with the assessment of innovative projects in the context of risk and uncertainty, topical issues of evaluation of innovative projects at the present stage of development of the Russian economy. By the example of the solution of the "crossing the river" is considering the possibility of using hierarchical models to address it. In what follows, and compares the priorities of different groups of factors are given by calculating the overall costs and benefits. The paper provides a rationale for combined use of four aspects: the beneficial aspects of the decision (the benefits and opportunities and negative (costs and risks that may lead to the decision in question.

  2. Probabilistic evaluation of uncertainties and risks in aerospace components

    Science.gov (United States)

    Shah, A. R.; Shiao, M. C.; Nagpal, V. K.; Chamis, C. C.

    1992-01-01

    This paper summarizes a methodology developed at NASA Lewis Research Center which computationally simulates the structural, material, and load uncertainties associated with Space Shuttle Main Engine (SSME) components. The methodology was applied to evaluate the scatter in static, buckling, dynamic, fatigue, and damage behavior of the SSME turbo pump blade. Also calculated are the probability densities of typical critical blade responses, such as effective stress, natural frequency, damage initiation, most probable damage path, etc. Risk assessments were performed for different failure modes, and the effect of material degradation on the fatigue and damage behaviors of a blade were calculated using a multi-factor interaction equation. Failure probabilities for different fatigue cycles were computed and the uncertainties associated with damage initiation and damage propagation due to different load cycle were quantified. Evaluations on the effects of mistuned blades on a rotor were made; uncertainties in the excitation frequency were found to significantly amplify the blade responses of a mistuned rotor. The effects of the number of blades on a rotor were studied. The autocorrelation function of displacements and the probability density function of the first passage time for deterministic and random barriers for structures subjected to random processes also were computed. A brief discussion was included on the future direction of probabilistic structural analysis.

  3. Review. Assessing uncertainty and risk in forest planning and decision support systems: review of classical methods and introduction of new approaches

    Directory of Open Access Journals (Sweden)

    M. Pasalodos-Tato

    2013-07-01

    Full Text Available Aim: Since forest planning is characterized by long time horizon and it typically involves large areas of land and numerous stakeholders, uncertainty and risk should play an important role when developing forest management plans. The aim of this study is to review different methods to deal with risk and uncertainty in forest planning, listing problems that forest managers may face during the preparation of management plans and trying to give recommendations in regard to the application of each method according to the problem case. The inclusion of risk and uncertainty in decision support systems is also analyzed.Area: It covers the temporal and spatial scale of forest planning, the spatial context, the participation process, the objectives dimensions and the good and services addressed.Material and methods: Several hundreds of articles dealing with uncertainty and risk were identified regarding different forestry-related topics and approaches. Form them, around 170 articles were further reviewed, categorized and evaluated.Main results: The study presents a thorough review and classification of methods and approaches to consider risk and uncertainty in forest planning. Moreover, new approaches are introduced, showing the opportunities that their application present in forest planning.Research highlights: The study can aid forest managers in the decision making process when designing a forest management plan considering risk and uncertainty.Keywords: operations research; optimal alternative; stochastic risk; endogenous risk; stand level; forest level.

  4. Modeling the Near-Term Risk of Climate Uncertainty: Interdependencies among the U.S. States

    Science.gov (United States)

    Lowry, T. S.; Backus, G.; Warren, D.

    2010-12-01

    Decisions made to address climate change must start with an understanding of the risk of an uncertain future to human systems, which in turn means understanding both the consequence as well as the probability of a climate induced impact occurring. In other words, addressing climate change is an exercise in risk-informed policy making, which implies that there is no single correct answer or even a way to be certain about a single answer; the uncertainty in future climate conditions will always be present and must be taken as a working-condition for decision making. In order to better understand the implications of uncertainty on risk and to provide a near-term rationale for policy interventions, this study estimates the impacts from responses to climate change on U.S. state- and national-level economic activity by employing a risk-assessment methodology for evaluating uncertain future climatic conditions. Using the results from the Intergovernmental Panel on Climate Change’s (IPCC) Fourth Assessment Report (AR4) as a proxy for climate uncertainty, changes in hydrology over the next 40 years were mapped and then modeled to determine the physical consequences on economic activity and to perform a detailed 70-industry analysis of the economic impacts among the interacting lower-48 states. The analysis determines industry-level effects, employment impacts at the state level, interstate population migration, consequences to personal income, and ramifications for the U.S. trade balance. The conclusions show that the average risk of damage to the U.S. economy from climate change is on the order of $1 trillion over the next 40 years, with losses in employment equivalent to nearly 7 million full-time jobs. Further analysis shows that an increase in uncertainty raises this risk. This paper will present the methodology behind the approach, a summary of the underlying models, as well as the path forward for improving the approach.

  5. Mental Health Experiences of Older Adults Living with HIV: Uncertainty, Stigma, and Approaches to Resilience.

    Science.gov (United States)

    Furlotte, Charles; Schwartz, Karen

    2017-06-01

    This study describes the mental health experiences of older adults living with HIV in Ottawa. Eleven participants aged 52 to 67 completed in-depth personal interviews. Mental health concerns pervaded the lives of these older adults. We identified three central themes common to the participants' stories: uncertainty, stigma, and resilience. For some of these participants, uncertainty impacting mental health centred on unexpected survival; interpretation of one's symptoms; and medical uncertainty. Participants' experiences of stigma included discrimination in health care interactions; misinformation; feeling stigmatized due to aspects of their physical appearance; compounded stigma; and anticipated stigma. Participants reported using several coping strategies, which we frame as individual approaches to resilience. These strategies include reducing the space that HIV takes up in one's life; making lifestyle changes to accommodate one's illness; and engaging with social support. These findings inform understandings of services for people aging with HIV who may experience mental health concerns.

  6. Perceived risk: rationality, uncertainty and scepticism

    International Nuclear Information System (INIS)

    Green, C.H.

    1981-01-01

    The subject is discussed under the headings: introduction; measuring what (deciding which outcomes are to be considered; personal safety, threat to health and safety (threat to society, threat to health)); accuracy of beliefs (distinction between immediate-in-effect hazards and delayed-in-effect hazards); the context of beliefs about risk (evolution of beliefs, changes in beliefs). Some references are made to nuclear power. (U.K.)

  7. Assessing the reliability of dose coefficients for exposure to radioiodine by members of the public, accounting for dosimetric and risk model uncertainties.

    Science.gov (United States)

    Puncher, M; Zhang, W; Harrison, J D; Wakeford, R

    2017-06-26

    Assessments of risk to a specific population group resulting from internal exposure to a particular radionuclide can be used to assess the reliability of the appropriate International Commission on Radiological Protection (ICRP) dose coefficients used as a radiation protection device for the specified exposure pathway. An estimate of the uncertainty on the associated risk is important for informing judgments on reliability; a derived uncertainty factor, UF, is an estimate of the 95% probable geometric difference between the best risk estimate and the nominal risk and is a useful tool for making this assessment. This paper describes the application of parameter uncertainty analysis to quantify uncertainties resulting from internal exposures to radioiodine by members of the public, specifically 1, 10 and 20-year old females from the population of England and Wales. Best estimates of thyroid cancer incidence risk (lifetime attributable risk) are calculated for ingestion or inhalation of 129 I and 131 I, accounting for uncertainties in biokinetic model and cancer risk model parameter values. These estimates are compared with the equivalent ICRP derived nominal age-, sex- and population-averaged estimates of excess thyroid cancer incidence to obtain UFs. Derived UF values for ingestion or inhalation of 131 I for 1 year, 10-year and 20-year olds are around 28, 12 and 6, respectively, when compared with ICRP Publication 103 nominal values, and 9, 7 and 14, respectively, when compared with ICRP Publication 60 values. Broadly similar results were obtained for 129 I. The uncertainties on risk estimates are largely determined by uncertainties on risk model parameters rather than uncertainties on biokinetic model parameters. An examination of the sensitivity of the results to the risk models and populations used in the calculations show variations in the central estimates of risk of a factor of around 2-3. It is assumed that the direct proportionality of excess thyroid cancer

  8. Economic–Environmental Sustainability in Building Projects: Introducing Risk and Uncertainty in LCCE and LCCA

    Directory of Open Access Journals (Sweden)

    Elena Fregonara

    2018-06-01

    Full Text Available The aim of this paper is to propose a methodology for supporting decision-making in the design stages of new buildings or in the retrofitting of existing heritages. The focus is on the evaluation of economic–environmental sustainability, considering the presence of risk and uncertainty. An application of risk analysis in conjunction with Life-Cycle Cost Analysis (LCCA is proposed for selecting the preferable solution between technological options, which represents a recent and poorly explored context of analysis. It is assumed that there is a presence of uncertainty in cost estimating, in terms of the Life-Cycle Cost Estimates (LCCEs and uncertainty in the technical performance of the life-cycle cost analysis. According to the probability analysis, which was solved through stochastic simulation and the Monte Carlo Method (MCM, risk and uncertainty are modeled as stochastic variables or as “stochastic relevant cost drivers”. Coherently, the economic–financial and energy–environmental sustainability is analyzed through the calculation of a conjoint “economic–environmental indicator”, in terms of the stochastic global cost. A case study of the multifunctional building glass façade project in Northern Italy is proposed. The application demonstrates that introducing flexibility into the input data and the duration of the service lives of components and the economic and environmental behavior of alternative scenarios can lead to opposite results compared to a deterministic analysis. The results give full evidence of the environmental variables’ capacity to significantly perturb the model output.

  9. Margins for geometric uncertainty around organs at risk in radiotherapy

    International Nuclear Information System (INIS)

    McKenzie, Alan; Herk, Marcel van; Mijnheer, Ben

    2002-01-01

    Background and purpose: ICRU Report 62 suggests drawing margins around organs at risk (ORs) to produce planning organ at risk volumes (PRVs) to account for geometric uncertainty in the radiotherapy treatment process. This paper proposes an algorithm for drawing such margins, and compares the recommended margin widths with examples from clinical practice and discusses the limitations of the approach. Method: The use of the PRV defined in this way is that, despite the geometric uncertainties, the dose calculated within the PRV by the treatment planning system can be used to represent the dose in the OR with a certain confidence level. A suitable level is where, in the majority of cases (90%), the dose-volume histogram of the PRV will not under-represent the high-dose components in the OR. In order to provide guidelines on how to do this in clinical practice, this paper distinguishes types of OR in terms of the tolerance doses relative to the prescription dose and suggests appropriate margins for serial-structure and parallel-structure ORs. Results: In some instances of large and parallel ORs, the clinician may judge that the complication risk in omitting a margin is acceptable. Otherwise, for all types of OR, systematic, treatment preparation uncertainties may be accommodated by an OR→PRV margin width of 1.3Σ. Here, Σ is the standard deviation of the combined systematic (treatment preparation) uncertainties. In the case of serial ORs or small, parallel ORs, the effects of blurring caused by daily treatment execution errors (set-up and organ motion) should be taken into account. Near a region of high dose, blurring tends to shift the isodoses away from the unblurred edge as shown on the treatment planning system by an amount that may be represented by 0.5σ. This margin may be used either to increase or to decrease the margin already calculated for systematic uncertainties, depending upon the size of the tolerance dose relative to the detailed planned dose

  10. APROBA-Plus: A probabilistic tool to evaluate and express uncertainty in hazard characterization and exposure assessment of substances.

    Science.gov (United States)

    Bokkers, Bas G H; Mengelers, Marcel J; Bakker, Martine I; Chiu, Weihsueh A; Slob, Wout

    2017-12-01

    To facilitate the application of probabilistic risk assessment, the WHO released the APROBA tool. This tool applies lognormal uncertainty distributions to the different aspects of the hazard characterization, resulting in a probabilistic health-based guidance value. The current paper describes an extension, APROBA-Plus, which combines the output from the probabilistic hazard characterization with the probabilistic exposure to rapidly characterize risk and its uncertainty. The uncertainty in exposure is graphically compared with the uncertainty in the target human dose, i.e. the dose that complies with the specified protection goals. APROBA-Plus is applied to several case studies, resulting in distinct outcomes and illustrating that APROBA-Plus could serve as a standard extension of routine risk assessments. By visualizing the uncertainties, APROBA-Plus provides a more transparent and informative outcome than the more usual deterministic approaches, so that risk managers can make better informed decisions. For example, APROBA-Plus can help in deciding whether risk-reducing measures are warranted or that a refined risk assessment would first be needed. If the latter, the tool can be used to prioritize possible refinements. APROBA-Plus may also be used to rank substances into different risk categories, based on potential health risks without being compromised by different levels of conservatism that may be associated with point estimates of risk. Copyright © 2017 Elsevier Ltd. All rights reserved.

  11. Assessment and presentation of uncertainties in probabilistic risk assessment: how should this be done

    International Nuclear Information System (INIS)

    Garlick, A.R.; Holloway, N.J.

    1987-01-01

    Despite continuing improvements in probabilistic risk assessment (PRA) techniques, PRA results, particularly those including degraded core analysis, will have maximum uncertainties of several orders of magnitude. This makes the expression of results, a matter no less important than their estimation. We put forward some ideas on the assessment and expression of highly uncertain quantities, such as probabilities of outcomes of a severe accident. These do not form a consistent set, but rather a number of alternative approaches aimed at stimulating discussion. These include non-probability expressions, such as fuzzy logic or Schafer's support and plausibility which abandon the purely probabilistic expression of risk for a more flexible type of expression, in which other types of measure are possible. The 'risk equivalent plant' concepts represent the opposite approach. Since uncertainty in a risk measure is in itself a form of risk, an attempt is made to define a 'risk equivalent' which is a risk with perfectly defined parameters, regarded (by means of suitable methods of judgement) as 'equally undesirable' with the actual plant. Some guidelines are given on the use of Bayesian methods in data-free or limited data situations. (author)

  12. Analysis of algal bloom risk with uncertainties in lakes by integrating self-organizing map and fuzzy information theory

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Qiuwen, E-mail: qchen@rcees.ac.cn [RCEES, Chinese Academy of Sciences, Shuangqinglu 18, Beijing 10085 (China); China Three Gorges University, Daxuelu 8, Yichang 443002 (China); CEER, Nanjing Hydraulics Research Institute, Guangzhoulu 223, Nanjing 210029 (China); Rui, Han; Li, Weifeng; Zhang, Yanhui [RCEES, Chinese Academy of Sciences, Shuangqinglu 18, Beijing 10085 (China)

    2014-06-01

    Algal blooms are a serious problem in waters, which damage aquatic ecosystems and threaten drinking water safety. However, the outbreak mechanism of algal blooms is very complex with great uncertainty, especially for large water bodies where environmental conditions have obvious variation in both space and time. This study developed an innovative method which integrated a self-organizing map (SOM) and fuzzy information diffusion theory to comprehensively analyze algal bloom risks with uncertainties. The Lake Taihu was taken as study case and the long-term (2004–2010) on-site monitoring data were used. The results showed that algal blooms in Taihu Lake were classified into four categories and exhibited obvious spatial–temporal patterns. The lake was mainly characterized by moderate bloom but had high uncertainty, whereas severe blooms with low uncertainty were observed in the northwest part of the lake. The study gives insight on the spatial–temporal dynamics of algal blooms, and should help government and decision-makers outline policies and practices on bloom monitoring and prevention. The developed method provides a promising approach to estimate algal bloom risks under uncertainties. - Highlights: • An innovative method is developed to analyze algal bloom risks with uncertainties. • The algal blooms in Taihu Lake showed obvious spatial and temporal patterns. • The lake is mainly characterized as moderate bloom but with high uncertainty. • Severe bloom with low uncertainty appeared occasionally in the northwest part. • The results provide important information to bloom monitoring and management.

  13. Public Health Concern on Fukushima Radiation Risks in Korea and Response Strategies

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Chaewon [Korea Institute of Radiological and Medical Sciences, 75 Nowon-Ro, Seoul 139-781 (Korea, Republic of)

    2014-07-01

    This paper reviews the characteristics of public perception on radiation risks by Fukushima Daiichi nuclear power plant accident and aims to suggest the appropriate strategies for minimizing social anxiety and managing the risk effectively on the basis of those features. In South Korea, the nearest country to Japan, fishery sales decreased 20% in 2013 due to consumers' fears over radiation contaminated seafood products. Public health concern is also increasing. The characteristics of public perception on the risk are the key factors of social anxiety, which are 'ongoing hazard' and 'uncertainty'. They can be translated same as the concepts of 'fear' and 'unknown risk', the psychometric factors of risk perception described in Slovic (1989)'s qualitative characteristics. News on a series of hazardous situations such as radioactive water leaks or radioactive steam at Fukushima is continually reported. Noting no expectation of accident settlement in near future, media coverage which has the expression of 'the maximum permissible level of radiation' without any translation of the measured dosimetric quantity causes the public's phobic fear. Uncertainties on health risks of low dose ionizing radiation in humans are not only the causes of fear but the challenges in building trust in risk communications. Rumours appear under ambiguous and uncertain situation with a lack of information. The communications among public authorities, related institutes, experts and the public become very important since the public health concern on radiation contamination turns into attention to the system of inspection, distribution, and regulation of imported food. The public shows deep interest in the safety standard of guidelines used in regulatory policy and safety management, which leads to a desire for participation in policy making process. Situational crisis communication theory can be applied to the situation quoted and

  14. Estimate of the uncertainties in the relative risk of secondary malignant neoplasms following proton therapy and intensity-modulated photon therapy

    International Nuclear Information System (INIS)

    Fontenot, Jonas D; Bloch, Charles; Followill, David; Titt, Uwe; Newhauser, Wayne D

    2010-01-01

    Theoretical calculations have shown that proton therapy can reduce the incidence of radiation-induced secondary malignant neoplasms (SMN) compared with photon therapy for patients with prostate cancer. However, the uncertainties associated with calculations of SMN risk had not been assessed. The objective of this study was to quantify the uncertainties in projected risks of secondary cancer following contemporary proton and photon radiotherapies for prostate cancer. We performed a rigorous propagation of errors and several sensitivity tests to estimate the uncertainty in the ratio of relative risk (RRR) due to the largest contributors to the uncertainty: the radiation weighting factor for neutrons, the dose-response model for radiation carcinogenesis and interpatient variations in absorbed dose. The interval of values for the radiation weighting factor for neutrons and the dose-response model were derived from the literature, while interpatient variations in absorbed dose were taken from actual patient data. The influence of each parameter on a baseline RRR value was quantified. Our analysis revealed that the calculated RRR was insensitive to the largest contributors to the uncertainty. Uncertainties in the radiation weighting factor for neutrons, the shape of the dose-risk model and interpatient variations in therapeutic and stray doses introduced a total uncertainty of 33% to the baseline RRR calculation.

  15. Making sense of perceptions of risk of diseases and vaccinations: a qualitative study combining models of health beliefs, decision-making and risk perception

    Directory of Open Access Journals (Sweden)

    Bond Lyndal

    2011-12-01

    Full Text Available Abstract Background Maintaining high levels of childhood vaccinations is important for public health. Success requires better understanding of parents' perceptions of diseases and consequent decisions about vaccinations, however few studies have considered this from the theoretical perspectives of risk perception and decision-making under uncertainty. The aim of this study was to examine the utility of subjective risk perception and decision-making theories to provide a better understanding of the differences between immunisers' and non-immunisers' health beliefs and behaviours. Methods In a qualitative study we conducted semi-structured in-depth interviews with 45 Australian parents exploring their experiences and perceptions of disease severity and susceptibility. Using scenarios about 'a new strain of flu' we explored how risk information was interpreted. Results We found that concepts of dread, unfamiliarity, and uncontrollability from the subjective perception of risk and ambiguity, optimistic control and omission bias from explanatory theories of decision-making under uncertainty were useful in understanding why immunisers, incomplete immunisers and non-immunisers interpreted severity and susceptibility to diseases and vaccine risk differently. Immunisers dreaded unfamiliar diseases whilst non-immunisers dreaded unknown, long term side effects of vaccines. Participants believed that the risks of diseases and complications from diseases are not equally spread throughout the community, therefore, when listening to reports of epidemics, it is not the number of people who are affected but the familiarity or unfamiliarity of the disease and the characteristics of those who have had the disease that prompts them to take preventive action. Almost all believed they themselves would not be at serious risk of the 'new strain of flu' but were less willing to take risks with their children's health. Conclusion This study has found that health messages

  16. Making sense of perceptions of risk of diseases and vaccinations: a qualitative study combining models of health beliefs, decision-making and risk perception.

    Science.gov (United States)

    Bond, Lyndal; Nolan, Terry

    2011-12-20

    Maintaining high levels of childhood vaccinations is important for public health. Success requires better understanding of parents' perceptions of diseases and consequent decisions about vaccinations, however few studies have considered this from the theoretical perspectives of risk perception and decision-making under uncertainty. The aim of this study was to examine the utility of subjective risk perception and decision-making theories to provide a better understanding of the differences between immunisers' and non-immunisers' health beliefs and behaviours. In a qualitative study we conducted semi-structured in-depth interviews with 45 Australian parents exploring their experiences and perceptions of disease severity and susceptibility. Using scenarios about 'a new strain of flu' we explored how risk information was interpreted. We found that concepts of dread, unfamiliarity, and uncontrollability from the subjective perception of risk and ambiguity, optimistic control and omission bias from explanatory theories of decision-making under uncertainty were useful in understanding why immunisers, incomplete immunisers and non-immunisers interpreted severity and susceptibility to diseases and vaccine risk differently. Immunisers dreaded unfamiliar diseases whilst non-immunisers dreaded unknown, long term side effects of vaccines. Participants believed that the risks of diseases and complications from diseases are not equally spread throughout the community, therefore, when listening to reports of epidemics, it is not the number of people who are affected but the familiarity or unfamiliarity of the disease and the characteristics of those who have had the disease that prompts them to take preventive action. Almost all believed they themselves would not be at serious risk of the 'new strain of flu' but were less willing to take risks with their children's health. This study has found that health messages about the risks of disease which are communicated as though there

  17. Incorporating the Technology Roadmap Uncertainties into the Project Risk Assessment

    International Nuclear Information System (INIS)

    Bonnema, B.E.

    2002-01-01

    This paper describes two methods, Technology Roadmapping and Project Risk Assessment, which were used to identify and manage the technical risks relating to the treatment of sodium bearing waste at the Idaho National Engineering and Environmental Laboratory. The waste treatment technology under consideration was Direct Vitrification. The primary objective of the Technology Roadmap is to identify technical data uncertainties for the technologies involved and to prioritize the testing or development studies to fill the data gaps. Similarly, project management's objective for a multi-million dollar construction project includes managing all the key risks in accordance to DOE O 413.3 - ''Program and Project Management for the Acquisition of Capital Assets.'' In the early stages, the Project Risk Assessment is based upon a qualitative analysis for each risk's probability and consequence. In order to clearly prioritize the work to resolve the technical issues identified in the Technology Roadmap, the issues must be cross- referenced to the project's Risk Assessment. This will enable the project to get the best value for the cost to mitigate the risks

  18. Characterizing uncertainty when evaluating risk management metrics: risk assessment modeling of Listeria monocytogenes contamination in ready-to-eat deli meats.

    Science.gov (United States)

    Gallagher, Daniel; Ebel, Eric D; Gallagher, Owen; Labarre, David; Williams, Michael S; Golden, Neal J; Pouillot, Régis; Dearfield, Kerry L; Kause, Janell

    2013-04-01

    This report illustrates how the uncertainty about food safety metrics may influence the selection of a performance objective (PO). To accomplish this goal, we developed a model concerning Listeria monocytogenes in ready-to-eat (RTE) deli meats. This application used a second order Monte Carlo model that simulates L. monocytogenes concentrations through a series of steps: the food-processing establishment, transport, retail, the consumer's home and consumption. The model accounted for growth inhibitor use, retail cross contamination, and applied an FAO/WHO dose response model for evaluating the probability of illness. An appropriate level of protection (ALOP) risk metric was selected as the average risk of illness per serving across all consumed servings-per-annum and the model was used to solve for the corresponding performance objective (PO) risk metric as the maximum allowable L. monocytogenes concentration (cfu/g) at the processing establishment where regulatory monitoring would occur. Given uncertainty about model inputs, an uncertainty distribution of the PO was estimated. Additionally, we considered how RTE deli meats contaminated at levels above the PO would be handled by the industry using three alternative approaches. Points on the PO distribution represent the probability that - if the industry complies with a particular PO - the resulting risk-per-serving is less than or equal to the target ALOP. For example, assuming (1) a target ALOP of -6.41 log10 risk of illness per serving, (2) industry concentrations above the PO that are re-distributed throughout the remaining concentration distribution and (3) no dose response uncertainty, establishment PO's of -4.98 and -4.39 log10 cfu/g would be required for 90% and 75% confidence that the target ALOP is met, respectively. The PO concentrations from this example scenario are more stringent than the current typical monitoring level of an absence in 25 g (i.e., -1.40 log10 cfu/g) or a stricter criteria of absence

  19. Dispelling urban myths about default uncertainty factors in chemical risk assessment--sufficient protection against mixture effects?

    Science.gov (United States)

    Martin, Olwenn V; Martin, Scholze; Kortenkamp, Andreas

    2013-07-01

    Assessing the detrimental health effects of chemicals requires the extrapolation of experimental data in animals to human populations. This is achieved by applying a default uncertainty factor of 100 to doses not found to be associated with observable effects in laboratory animals. It is commonly assumed that the toxicokinetic and toxicodynamic sub-components of this default uncertainty factor represent worst-case scenarios and that the multiplication of those components yields conservative estimates of safe levels for humans. It is sometimes claimed that this conservatism also offers adequate protection from mixture effects. By analysing the evolution of uncertainty factors from a historical perspective, we expose that the default factor and its sub-components are intended to represent adequate rather than worst-case scenarios. The intention of using assessment factors for mixture effects was abandoned thirty years ago. It is also often ignored that the conservatism (or otherwise) of uncertainty factors can only be considered in relation to a defined level of protection. A protection equivalent to an effect magnitude of 0.001-0.0001% over background incidence is generally considered acceptable. However, it is impossible to say whether this level of protection is in fact realised with the tolerable doses that are derived by employing uncertainty factors. Accordingly, it is difficult to assess whether uncertainty factors overestimate or underestimate the sensitivity differences in human populations. It is also often not appreciated that the outcome of probabilistic approaches to the multiplication of sub-factors is dependent on the choice of probability distributions. Therefore, the idea that default uncertainty factors are overly conservative worst-case scenarios which can account both for the lack of statistical power in animal experiments and protect against potential mixture effects is ill-founded. We contend that precautionary regulation should provide an

  20. Flood risk assessment and robust management under deep uncertainty: Application to Dhaka City

    Science.gov (United States)

    Mojtahed, Vahid; Gain, Animesh Kumar; Giupponi, Carlo

    2014-05-01

    The socio-economic changes as well as climatic changes have been the main drivers of uncertainty in environmental risk assessment and in particular flood. The level of future uncertainty that researchers face when dealing with problems in a future perspective with focus on climate change is known as Deep Uncertainty (also known as Knightian uncertainty), since nobody has already experienced and undergone those changes before and our knowledge is limited to the extent that we have no notion of probabilities, and therefore consolidated risk management approaches have limited potential.. Deep uncertainty is referred to circumstances that analysts and experts do not know or parties to decision making cannot agree on: i) the appropriate models describing the interaction among system variables, ii) probability distributions to represent uncertainty about key parameters in the model 3) how to value the desirability of alternative outcomes. The need thus emerges to assist policy-makers by providing them with not a single and optimal solution to the problem at hand, such as crisp estimates for the costs of damages of natural hazards considered, but instead ranges of possible future costs, based on the outcomes of ensembles of assessment models and sets of plausible scenarios. Accordingly, we need to substitute optimality as a decision criterion with robustness. Under conditions of deep uncertainty, the decision-makers do not have statistical and mathematical bases to identify optimal solutions, while instead they should prefer to implement "robust" decisions that perform relatively well over all conceivable outcomes out of all future unknown scenarios. Under deep uncertainty, analysts cannot employ probability theory or other statistics that usually can be derived from observed historical data and therefore, we turn to non-statistical measures such as scenario analysis. We construct several plausible scenarios with each scenario being a full description of what may happen

  1. The Roles of Three Types of Knowledge and Perceived Uncertainty in Explaining Risk Perception, Acceptability, and Self-Protective Response—A Case Study on Endocrine Disrupting Surfactants

    Directory of Open Access Journals (Sweden)

    Hien Ho

    2018-02-01

    Full Text Available The ubiquitous surfactants nonylphenol (NP and its ethoxylates (NPEOs, which are known as endocrine disrupters, have appeared in the lists of restricted chemical substances, monitoring programs, and environmental quality standards of many countries due to their adverse effects. Recent studies have reported alarming levels of NP, as the final metabolite of NPEOs, in Vietnamese urban waters, whilst response to this issue is negligible. With the aim of addressing how the public perceives and expects to avoid the risk of endocrine disrupting surfactants (EDSs, the study tested the hypothesized roles of specific knowledge, general knowledge, and perceived uncertainty using structural equation modelling. The findings revealed that different types of knowledge played certain roles in explaining risk perception, risk acceptability, and self-protective response, which are distinguished by experience amongst the public. Evidence of the mediating role that perceived uncertainty may play in the decrease of risk perception and the increase of risk unacceptance has been provided. The insights gained from the study may help answer why the public are in favor of taking non-diet-related self-protective measures rather than changing their dietary habits, which illustrates a comparison with the basis of health belief model. The needs for building cognitive capacity amongst the public, particularly pregnant women and young mothers, and risk communication concerning endocrine disrupting contamination linked to reproductive health are highlighted.

  2. Making sense of perceptions of risk of diseases and vaccinations: a qualitative study combining models of health beliefs, decision-making and risk perception

    OpenAIRE

    Bond Lyndal; Nolan Terry

    2011-01-01

    Abstract Background Maintaining high levels of childhood vaccinations is important for public health. Success requires better understanding of parents' perceptions of diseases and consequent decisions about vaccinations, however few studies have considered this from the theoretical perspectives of risk perception and decision-making under uncertainty. The aim of this study was to examine the utility of subjective risk perception and decision-making theories to provide a better understanding o...

  3. Experiences of Uncertainty in Men With an Elevated PSA.

    Science.gov (United States)

    Biddle, Caitlin; Brasel, Alicia; Underwood, Willie; Orom, Heather

    2015-05-15

    A significant proportion of men, ages 50 to 70 years, have, and continue to receive prostate specific antigen (PSA) tests to screen for prostate cancer (PCa). Approximately 70% of men with an elevated PSA level will not subsequently be diagnosed with PCa. Semistructured interviews were conducted with 13 men with an elevated PSA level who had not been diagnosed with PCa. Uncertainty was prominent in men's reactions to the PSA results, stemming from unanswered questions about the PSA test, PCa risk, and confusion about their management plan. Uncertainty was exacerbated or reduced depending on whether health care providers communicated in lay and empathetic ways, and provided opportunities for question asking. To manage uncertainty, men engaged in information and health care seeking, self-monitoring, and defensive cognition. Results inform strategies for meeting informational needs of men with an elevated PSA and confirm the primary importance of physician communication behavior for open information exchange and uncertainty reduction. © The Author(s) 2015.

  4. A new uncertainty importance measure

    International Nuclear Information System (INIS)

    Borgonovo, E.

    2007-01-01

    Uncertainty in parameters is present in many risk assessment problems and leads to uncertainty in model predictions. In this work, we introduce a global sensitivity indicator which looks at the influence of input uncertainty on the entire output distribution without reference to a specific moment of the output (moment independence) and which can be defined also in the presence of correlations among the parameters. We discuss its mathematical properties and highlight the differences between the present indicator, variance-based uncertainty importance measures and a moment independent sensitivity indicator previously introduced in the literature. Numerical results are discussed with application to the probabilistic risk assessment model on which Iman [A matrix-based approach to uncertainty and sensitivity analysis for fault trees. Risk Anal 1987;7(1):22-33] first introduced uncertainty importance measures

  5. Do (un)certainty appraisal tendencies reverse the influence of emotions on risk taking in sequential tasks?

    Science.gov (United States)

    Bagneux, Virginie; Bollon, Thierry; Dantzer, Cécile

    2012-01-01

    According to the Appraisal-Tendency Framework (Han, Lerner, & Keltner, 2007), certainty-associated emotions increase risk taking compared with uncertainty-associated emotions. To date, this general effect has only been shown in static judgement and decision-making paradigms; therefore, the present study tested the effect of certainty on risk taking in a sequential decision-making task. We hypothesised that the effect would be reversed due to the kind of processing involved, as certainty is considered to encourage heuristic processing that takes into account the emotional cues arising from previous decisions, whereas uncertainty leads to more systematic processing. One hundred and one female participants were induced to feel one of three emotions (film clips) before performing a decision-making task involving risk (Game of Dice Task; Brand et al., 2005). As expected, the angry and happy participants (certainty-associated emotions) were more likely than the fearful participants (uncertainty-associated emotion) to make safe decisions (vs. risky decisions).

  6. Health risk assessment for nanoparticles: A case for using expert judgment

    International Nuclear Information System (INIS)

    Kandlikar, Milind; Ramachandran, Gurumurthy; Maynard, Andrew; Murdock, Barbara; Toscano, William A.

    2007-01-01

    Uncertainties in conventional quantitative risk assessment typically relate to values of parameters in risk models. For many environmental contaminants, there is a lack of sufficient information about multiple components of the risk assessment framework. In such cases, the use of default assumptions and extrapolations to fill in the data gaps is a common practice. Nanoparticle risks, however, pose a new form of risk assessment challenge. Besides a lack of data, there is deep scientific uncertainty regarding every aspect of the risk assessment framework: (a) particle characteristics that may affect toxicity; (b) their fate and transport through the environment; (c) the routes of exposure and the metrics by which exposure ought to be measured; (d) the mechanisms of translocation to different parts of the body; and (e) the mechanisms of toxicity and disease. In each of these areas, there are multiple and competing models and hypotheses. These are not merely parametric uncertainties but uncertainties about the choice of the causal mechanisms themselves and the proper model variables to be used, i.e., structural uncertainties. While these uncertainties exist for PM2.5 as well, risk assessment for PM2.5 has avoided dealing with these issues because of a plethora of epidemiological studies. However, such studies don't exist for the case of nanoparticles. Even if such studies are done in the future, they will be very specific to a particular type of engineered nanoparticle and not generalizable to other nanoparticles. Therefore, risk assessment for nanoparticles will have to deal with the various uncertainties that were avoided in the case of PM2.5. Consequently, uncertainties in estimating risks due to nanoparticle exposures may be characterized as 'extreme'. This paper proposes a methodology by which risk analysts can cope with such extreme uncertainty. One way to make these problems analytically tractable is to use expert judgment approaches to study the degree of

  7. Risk classification and uncertainty propagation for virtual water distribution systems

    International Nuclear Information System (INIS)

    Torres, Jacob M.; Brumbelow, Kelly; Guikema, Seth D.

    2009-01-01

    While the secrecy of real water distribution system data is crucial, it poses difficulty for research as results cannot be publicized. This data includes topological layouts of pipe networks, pump operation schedules, and water demands. Therefore, a library of virtual water distribution systems can be an important research tool for comparative development of analytical methods. A virtual city, 'Micropolis', has been developed, including a comprehensive water distribution system, as a first entry into such a library. This virtual city of 5000 residents is fully described in both geographic information systems (GIS) and EPANet hydraulic model frameworks. A risk classification scheme and Monte Carlo analysis are employed for an attempted water supply contamination attack. Model inputs to be considered include uncertainties in: daily water demand, seasonal demand, initial storage tank levels, the time of day a contamination event is initiated, duration of contamination event, and contaminant quantity. Findings show that reasonable uncertainties in model inputs produce high variability in exposure levels. It is also shown that exposure level distributions experience noticeable sensitivities to population clusters within the contaminant spread area. High uncertainties in exposure patterns lead to greater resources needed for more effective mitigation strategies.

  8. Local scale multiple quantitative risk assessment and uncertainty evaluation in a densely urbanised area (Brescia, Italy

    Directory of Open Access Journals (Sweden)

    S. Lari

    2012-11-01

    Full Text Available The study of the interactions between natural and anthropogenic risks is necessary for quantitative risk assessment in areas affected by active natural processes, high population density and strong economic activities.

    We present a multiple quantitative risk assessment on a 420 km2 high risk area (Brescia and surroundings, Lombardy, Northern Italy, for flood, seismic and industrial accident scenarios. Expected economic annual losses are quantified for each scenario and annual exceedance probability-loss curves are calculated. Uncertainty on the input variables is propagated by means of three different methodologies: Monte-Carlo-Simulation, First Order Second Moment, and point estimate.

    Expected losses calculated by means of the three approaches show similar values for the whole study area, about 64 000 000 € for earthquakes, about 10 000 000 € for floods, and about 3000 € for industrial accidents. Locally, expected losses assume quite different values if calculated with the three different approaches, with differences up to 19%.

    The uncertainties on the expected losses and their propagation, performed with the three methods, are compared and discussed in the paper. In some cases, uncertainty reaches significant values (up to almost 50% of the expected loss. This underlines the necessity of including uncertainty in quantitative risk assessment, especially when it is used as a support for territorial planning and decision making. The method is developed thinking at a possible application at a regional-national scale, on the basis of data available in Italy over the national territory.

  9. Accounting for data uncertainties in comparing risks from energy systems

    International Nuclear Information System (INIS)

    Hauptmanns, Ulrich

    1998-01-01

    Data and models for risk comparisons are uncertain and this is true all the more the larger the time horizon contemplated. Statistical methods are presented for dealing with data uncertainties thus providing a broader foundation for decisions. Nevertheless, it has to be borne in mind that no method exists to account for the 'unforeseeable' which is always present in decision making with respect to the far future. (author)

  10. Use of screening techniques to reduce uncertainty in risk assessment at a former manufactured gas plant site

    International Nuclear Information System (INIS)

    Logan, C.M.; Walden, R.H.; Baker, S.R.; Pekar, Z.; LaKind, J.S.; MacFarlane, I.D.

    1995-01-01

    Preliminary analysis of risks from a former manufactured gas plant (MGP) site revealed six media associated with potential exposure pathways: soils, air, surface water, groundwater, estuarine sediments, and aquatic biota. Contaminants of concern (COCs) include polycyclic aromatic hydrocarbons, volatile organic hydrocarbons, metals, cyanide, and PCBs. Available chemical data, including site-specific measurements and existing data from other sources (e.g., agency monitoring programs, Chesapeake Bay Program), were evaluated for potential utility in risk assessment. Where sufficient data existed, risk calculations were performed using central tendency and reasonable maximum exposure estimates. Where site-specific data were not available, risks were estimated using conservatively high default assumptions for dose and/or exposure duration. Because of the large number of potential exposure pathways and COCs, a sensitivity analysis was conducted to determine which information most influences risk assessment outcome so that any additional data collection to reduce uncertainty can be cost-effectively targeted. The sensitivity analysis utilized two types of information: (1) the impact that uncertainty in risk input values has on output risk estimates, and (2) the potential improvement in key risk input values, and consequently output values, if better site-specific data were available. A decision matrix using both quantitative and qualitative information was developed to prioritize sampling strategies to minimize uncertainty in the final risk assessment

  11. Experiences of liver health related uncertainty and self-reported stress among people who inject drugs living with hepatitis C virus: a qualitative study.

    Science.gov (United States)

    Goutzamanis, Stelliana; Doyle, Joseph S; Thompson, Alexander; Dietze, Paul; Hellard, Margaret; Higgs, Peter

    2018-04-02

    People who inject drugs (PWID) are most at risk of hepatitis C virus infection in Australia. The introduction of transient elastography (TE) (measuring hepatitis fibrosis) and direct acting antiviral medications will likely alter the experience of living with hepatitis C. We aimed to explore positive and negative influences on wellbeing and stress among PWID with hepatitis C. The Treatment and Prevention (TAP) study examines the feasibility of treating hepatitis C mono-infected PWID in community settings. Semi-structured interviews were conducted with 16 purposively recruited TAP participants. Participants were aware of their hepatitis C seropositive status and had received fibrosis assessment (measured by TE) prior to interview. Questions were open-ended, focusing on the impact of health status on wellbeing and self-reported stress. Interviews were voice recorded, transcribed verbatim and thematically analysed, guided by Mishel's (1988) theory of Uncertainty in Illness. In line with Mishel's theory of Uncertainty in Illness all participants reported hepatitis C-related uncertainty, particularly mis-information or a lack of knowledge surrounding liver health and the meaning of TE results. Those with greater fibrosis experienced an extra layer of prognostic uncertainty. Experiences of uncertainty were a key motivation to seek treatment, which was seen as a way to regain some stability in life. Treatment completion alleviated hepatitis C-related stress, and promoted feelings of empowerment and confidence in addressing other life challenges. TE scores seemingly provide some certainty. However, when paired with limited knowledge, particularly among people with severe fibrosis, TE may be a source of uncertainty and increased personal stress. This suggests the need for simple education programs and resources on liver health to minimise stress.

  12. Uncertainties in smart grids behavior and modeling: What are the risks and vulnerabilities? How to analyze them?

    Energy Technology Data Exchange (ETDEWEB)

    Zio, Enrico, E-mail: enrico.zio@ecp.fr [Ecole Centrale Paris - Supelec, Paris (France); Politecnico di Milano, Milano (Italy); Aven, Terje, E-mail: terje.aven@uis.no [University of Stavanger, Stavanger (Norway)

    2011-10-15

    This paper looks into the future world of smart grids from a rather different perspective than usual: that of uncertainties and the related risks and vulnerabilities. An analysis of the foreseen constituents of smart grids and of the technological, operational, economical and policy-driven challenges is carried out to identify and characterize the related uncertainties and associated risks and vulnerabilities. The focus is on the challenges posed to the representation and treatment of uncertainties in the performance assessment of such systems, given their complexity and high-level of integration of novel technologies. A general framework of analysis is proposed. - Highlights: > We have looked into the development and operation of smart grids for power distribution. > We have identified a number of uncertainties, which are expected to play an influential role. > We have provided some guidelines to address these issues, based on probability intervals.

  13. Review. Assessing uncertainty and risk in forest planning and decision support systems: review of classical methods and introduction of innovative approaches

    Energy Technology Data Exchange (ETDEWEB)

    Pasalodos-Tato, M.; Makinen, A.; Garcia-Gonzalez, J.; Borges, J. G.; Lamas, T.; Eriksson, L. O.

    2013-09-01

    Aim: Since forest planning is characterized by long time horizon and it typically involves large areas of land and numerous stake holders, uncertainty and risk should play an important role when developing forest management plans. The aim of this study is to review different methods to deal with risk and uncertainty in forest planning, listing problems that forest managers may face during the preparation of management plans and trying to give recommendations in regard to the application of each method according to the problem case. The inclusion of risk and uncertainty in decision support systems is also analyzed. Area: It covers the temporal and spatial scale of forest planning, the spatial context, the participation process, the objectives dimensions and the good and services addressed. Material and methods: Several hundreds of articles dealing with uncertainty and risk were identified regarding different forestry-related topics and approaches. Form them, around 170 articles were further reviewed, categorized and evaluated. Main results: The study presents a thorough review and classification of methods and approaches to consider risk and uncertainty in forest planning. Moreover, new approaches are introduced, showing the opportunities that their application presents in forest planning. Research highlights: The study can aid forest managers in the decision making process when designing a forest management plan considering risk and uncertainty. (Author)

  14. Investing in finite-life carbon emissions reduction program under risk and idiosyncratic uncertainty

    International Nuclear Information System (INIS)

    Fouilloux, Jessica; Moraux, Franck; Viviani, Jean-Laurent

    2015-01-01

    This paper aims at emphasizing the ability of new frameworks of real option model to highlight key characteristics of industrial Carbon Emissions Reduction Program investment decision. We develop both theoretical arguments and numerical simulations with structural parameters calibrated on real-life data. We find that both radical uncertainty and risk lead to speed-up green investments, compared to the predictions of real option models that are normally used in green investment literature. The conventional “wait and see” attitude, questioned in recent developments of the real option theory, is not validated. In conclusion, our results should foster companies to implement green investments and help governments to define appropriate incentives to encourage green investments. Of particular note, the paper highlights that finance theory is not necessarily an obstacle to green investment decisions. -- Highlights: •We use real option model to identify key features of CERP investment decision. •We determine the optimal carbon price threshold to undertake a CERP. •Investment decision is a non-monotonic function of idiosyncratic uncertainty. •Increasing uncertainty until a moderate level can accelerate investment decision. •Decreasing idiosyncratic risk can accelerate investment decision

  15. Stochastic fuzzy environmental risk characterization of uncertainty and variability in risk assessments: A case study of polycyclic aromatic hydrocarbons in soil at a petroleum-contaminated site in China

    International Nuclear Information System (INIS)

    Hu, Yan; Wang, Zesen; Wen, Jingya; Li, Yu

    2016-01-01

    Highlights: • Deal with environmental quality guidelines absence in risk characterization. • Quantitative represention of uncertainty from environmental quality guidelines. • Quantitative represention of variability from contaminant exposure concentrations. • Establishment of stochastic-fuzzy environmental risk characterization approach framework. - Abstract: Better decisions are made using risk assessment models when uncertainty and variability are explicitly acknowledged. Uncertainty caused by a lack of uniform and scientifically supported environmental quality guidelines and variability in the degree of exposure of environmental systems to contaminants are here incorporated in a stochastic fuzzy environmental risk characterization (SFERC) approach. The approach is based on quotient probability distribution and environmental risk level fuzzy membership function methods. The SFERC framework was used to characterize the environmental risks posed by 16 priority polycyclic aromatic hydrocarbons (PAHs) in soil at a typical petroleum-contaminated site in China. This relied on integrating data from the literature and field and laboratory experiments. The environmental risk levels posed by the PAHs under four risk scenarios were determined using the SFERC approach, using “residential land” and “industrial land” environmental quality guidelines under “loose” and “strict” strictness parameters. The results showed that environmental risks posed by PAHs in soil are primarily caused by oil exploitation, traffic emissions, and coal combustion. The SFERC approach is an effective tool for characterizing uncertainty and variability in environmental risk assessments and for managing contaminated sites.

  16. Stochastic fuzzy environmental risk characterization of uncertainty and variability in risk assessments: A case study of polycyclic aromatic hydrocarbons in soil at a petroleum-contaminated site in China

    Energy Technology Data Exchange (ETDEWEB)

    Hu, Yan [MOE Key Laboratory of Regional Energy Systems Optimization, Resources and Environmental Research Academy, North China Electric Power University, Beijing 102206 (China); State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environment Sciences, Beijing 100012 (China); Wang, Zesen [MOE Key Laboratory of Regional Energy Systems Optimization, Resources and Environmental Research Academy, North China Electric Power University, Beijing 102206 (China); Wen, Jingya [MOE Key Laboratory of Regional Energy Systems Optimization, Resources and Environmental Research Academy, North China Electric Power University, Beijing 102206 (China); Institute of Hydropower and Environment Research, Beijing 100012 (China); Li, Yu, E-mail: liyuxx8@hotmail.com [MOE Key Laboratory of Regional Energy Systems Optimization, Resources and Environmental Research Academy, North China Electric Power University, Beijing 102206 (China)

    2016-10-05

    Highlights: • Deal with environmental quality guidelines absence in risk characterization. • Quantitative represention of uncertainty from environmental quality guidelines. • Quantitative represention of variability from contaminant exposure concentrations. • Establishment of stochastic-fuzzy environmental risk characterization approach framework. - Abstract: Better decisions are made using risk assessment models when uncertainty and variability are explicitly acknowledged. Uncertainty caused by a lack of uniform and scientifically supported environmental quality guidelines and variability in the degree of exposure of environmental systems to contaminants are here incorporated in a stochastic fuzzy environmental risk characterization (SFERC) approach. The approach is based on quotient probability distribution and environmental risk level fuzzy membership function methods. The SFERC framework was used to characterize the environmental risks posed by 16 priority polycyclic aromatic hydrocarbons (PAHs) in soil at a typical petroleum-contaminated site in China. This relied on integrating data from the literature and field and laboratory experiments. The environmental risk levels posed by the PAHs under four risk scenarios were determined using the SFERC approach, using “residential land” and “industrial land” environmental quality guidelines under “loose” and “strict” strictness parameters. The results showed that environmental risks posed by PAHs in soil are primarily caused by oil exploitation, traffic emissions, and coal combustion. The SFERC approach is an effective tool for characterizing uncertainty and variability in environmental risk assessments and for managing contaminated sites.

  17. Cognitive Processes in Decisions Under Risk Are Not the Same As in Decisions Under Uncertainty

    Directory of Open Access Journals (Sweden)

    Kirsten G Volz

    2012-07-01

    Full Text Available We deal with risk versus uncertainty, a distinction that is of fundamental importance for cognitive neuroscience yet largely neglected. In a world of risk (small world, all alternatives, consequences, and probabilities are known. In uncertain (large worlds, some of this information is unknown or unknowable. Most of cognitive neuroscience studies exclusively study the neural correlates for decisions under risk (e.g., lotteries, with the tacit implication that understanding these would lead to an understanding of decision making in general. First, we show that normative strategies for decisions under risk do not generalize to uncertain worlds, where simple heuristics are often the more accurate strategies. Second, we argue that the cognitive processes for making decisions in a world of risk are not the same as those for dealing with uncertainty. Because situations with known risks are the exception rather than the rule in human evolution, it is unlikely that our brains are adapted to them. We therefore suggest a paradigm shift towards studying decision processes in uncertain worlds and provide first examples.

  18. Deep Uncertainties in Sea-Level Rise and Storm Surge Projections: Implications for Coastal Flood Risk Management.

    Science.gov (United States)

    Oddo, Perry C; Lee, Ben S; Garner, Gregory G; Srikrishnan, Vivek; Reed, Patrick M; Forest, Chris E; Keller, Klaus

    2017-09-05

    Sea levels are rising in many areas around the world, posing risks to coastal communities and infrastructures. Strategies for managing these flood risks present decision challenges that require a combination of geophysical, economic, and infrastructure models. Previous studies have broken important new ground on the considerable tensions between the costs of upgrading infrastructure and the damages that could result from extreme flood events. However, many risk-based adaptation strategies remain silent on certain potentially important uncertainties, as well as the tradeoffs between competing objectives. Here, we implement and improve on a classic decision-analytical model (Van Dantzig 1956) to: (i) capture tradeoffs across conflicting stakeholder objectives, (ii) demonstrate the consequences of structural uncertainties in the sea-level rise and storm surge models, and (iii) identify the parametric uncertainties that most strongly influence each objective using global sensitivity analysis. We find that the flood adaptation model produces potentially myopic solutions when formulated using traditional mean-centric decision theory. Moving from a single-objective problem formulation to one with multiobjective tradeoffs dramatically expands the decision space, and highlights the need for compromise solutions to address stakeholder preferences. We find deep structural uncertainties that have large effects on the model outcome, with the storm surge parameters accounting for the greatest impacts. Global sensitivity analysis effectively identifies important parameter interactions that local methods overlook, and that could have critical implications for flood adaptation strategies. © 2017 Society for Risk Analysis.

  19. Health risk assessment of dichloromethane (methylene chloride) in California ground water

    International Nuclear Information System (INIS)

    Bogen, K.T.; Hall, L.C.; Wright, K.; McKone, T.E.

    1992-01-01

    This document presents an assessment of potential health risks associated with exposure to dichloromethane (DCM) dissolved in California drinking water, focusing primarily on information relevant to a determination of potential cancer risk that may be associated with such exposures to DCM. This assessment is being provided to the California Environmental Protection Agency for the development of drinking-water standards to manage the health risks of DCM exposures. Other assessments required in the risk-management process include analyses of the technical and economic feasibilities of treating water supplies contaminated with DCM. The primary goal of this health-risk assessment is to evaluate scientifically plausible dose-response relationships for observed and potential DCM-induced cancer in order to define dose rates that can be used to establish standards that win protect members of the general public from this chronic toxicity endpoint resulting solely from groundwater-based exposures to DCM, based on information obtained from the scientific literature. The document consists of seven sections, plus one supporting appendix. Each section provides information that can be used to develop DCM drinking-water standards that will safeguard human health. Evaluation of this information in support of specific groundwater safety standards for DCM was not conducted in this report; rather, the basis for selection of alternative standards, along with a narrative description of certain key sources of underlying uncertainty, are presented for evaluation through the regulatory risk-management process

  20. Demonstration uncertainty/sensitivity analysis using the health and economic consequence model CRAC2

    International Nuclear Information System (INIS)

    Alpert, D.J.; Iman, R.L.; Johnson, J.D.; Helton, J.C.

    1984-12-01

    The techniques for performing uncertainty/sensitivity analyses compiled as part of the MELCOR program appear to be well suited for use with a health and economic consequence model. Two replicate samples of size 50 gave essentially identical results, indicating that for this case, a Latin hypercube sample of size 50 seems adequate to represent the distribution of results. Though the intent of this study was a demonstration of uncertainty/sensitivity analysis techniques, a number of insights relevant to health and economic consequence modeling can be gleaned: uncertainties in early deaths are significantly greater than uncertainties in latent cancer deaths; though the magnitude of the source term is the largest source of variation in estimated distributions of early deaths, a number of additional parameters are also important; even with the release fractions for a full SST1, one quarter of the CRAC2 runs gave no early deaths; and comparison of the estimates of mean early deaths for a full SST1 release in this study with those of recent point estimates for similar conditions indicates that the recent estimates may be significant overestimations of early deaths. Estimates of latent cancer deaths, however, are roughly comparable. An analysis of the type described here can provide insights in a number of areas. First, the variability in the results gives an indication of the potential uncertainty associated with the calculations. Second, the sensitivity of the results to assumptions about the input variables can be determined. Research efforts can then be concentrated on reducing the uncertainty in the variables which are the largest contributors to uncertainty in results

  1. Human Health Risk Assessment of Pharmaceuticals in Water: Issues and Challenges Ahead

    Directory of Open Access Journals (Sweden)

    Arun Kumar

    2010-11-01

    Full Text Available This study identified existing issues related to quantitative pharmaceutical risk assessment (QPhRA, hereafter for pharmaceuticals in water and proposed possible solutions by analyzing methodologies and findings of different published QPhRA studies. Retrospective site-specific QPhRA studies from different parts of the world (U.S.A., United Kingdom, Europe, India, etc. were reviewed in a structured manner to understand different assumptions, outcomes obtained and issues, identified/addressed/raised by the different QPhRA studies. Till date, most of the published studies have concluded that there is no appreciable risk to human health during environmental exposures of pharmaceuticals; however, attention is still required to following identified issues: (1 Use of measured versus predicted pharmaceutical concentration, (2 Identification of pharmaceuticals-of-concern and compounds needing special considerations, (3 Use of source water versus finished drinking water-related exposure scenarios, (4 Selection of representative exposure routes, (5 Valuation of uncertainty factors, and (6 Risk assessment for mixture of chemicals. To close the existing data and methodology gaps, this study proposed possible ways to address and/or incorporation these considerations within the QPhRA framework; however, more research work is still required to address issues, such as incorporation of short-term to long-term extrapolation and mixture effects in the QPhRA framework. Specifically, this study proposed a development of a new “mixture effects-related uncertainty factor” for mixture of chemicals (i.e., mixUFcomposite, similar to an uncertainty factor of a single chemical, within the QPhRA framework. In addition to all five traditionally used uncertainty factors, this uncertainty factor is also proposed to include concentration effects due to presence of different range of concentration levels of pharmaceuticals in a mixture. However, further work is required to

  2. Optimal natural resources management under uncertainty with catastrophic risk

    Energy Technology Data Exchange (ETDEWEB)

    Motoh, Tsujimura [Graduate School of Economics, Kyoto University, Yoshida-honmochi, Sakyo-ku, Kyoto 606-8501 (Japan)

    2004-05-01

    We examine an optimal natural resources management problem under uncertainty with catastrophic risk and investigate the optimal rate of use of a natural resource. For this purpose, we use stochastic control theory. We assume that, until a catastrophic event occurs, the stock of the natural resource is governed by a stochastic differential equation. We describe the catastrophic phenomenon as a Poisson process. From this analysis, we show the optimal rate of use of the natural resource in explicit form. Furthermore, we present comparative static results for the optimal rate of use of the natural resource.

  3. Optimal natural resources management under uncertainty with catastrophic risk

    International Nuclear Information System (INIS)

    Motoh, Tsujimura

    2004-01-01

    We examine an optimal natural resources management problem under uncertainty with catastrophic risk and investigate the optimal rate of use of a natural resource. For this purpose, we use stochastic control theory. We assume that, until a catastrophic event occurs, the stock of the natural resource is governed by a stochastic differential equation. We describe the catastrophic phenomenon as a Poisson process. From this analysis, we show the optimal rate of use of the natural resource in explicit form. Furthermore, we present comparative static results for the optimal rate of use of the natural resource

  4. Uncertainty Estimation Cheat Sheet for Probabilistic Risk Assessment

    Science.gov (United States)

    Britton, Paul T.; Al Hassan, Mohammad; Ring, Robert W.

    2017-01-01

    "Uncertainty analysis itself is uncertain, therefore, you cannot evaluate it exactly," Source Uncertain Quantitative results for aerospace engineering problems are influenced by many sources of uncertainty. Uncertainty analysis aims to make a technical contribution to decision-making through the quantification of uncertainties in the relevant variables as well as through the propagation of these uncertainties up to the result. Uncertainty can be thought of as a measure of the 'goodness' of a result and is typically represented as statistical dispersion. This paper will explain common measures of centrality and dispersion; and-with examples-will provide guidelines for how they may be estimated to ensure effective technical contributions to decision-making.

  5. Dispelling urban myths about default uncertainty factors in chemical risk assessment – sufficient protection against mixture effects?

    Science.gov (United States)

    2013-01-01

    Assessing the detrimental health effects of chemicals requires the extrapolation of experimental data in animals to human populations. This is achieved by applying a default uncertainty factor of 100 to doses not found to be associated with observable effects in laboratory animals. It is commonly assumed that the toxicokinetic and toxicodynamic sub-components of this default uncertainty factor represent worst-case scenarios and that the multiplication of those components yields conservative estimates of safe levels for humans. It is sometimes claimed that this conservatism also offers adequate protection from mixture effects. By analysing the evolution of uncertainty factors from a historical perspective, we expose that the default factor and its sub-components are intended to represent adequate rather than worst-case scenarios. The intention of using assessment factors for mixture effects was abandoned thirty years ago. It is also often ignored that the conservatism (or otherwise) of uncertainty factors can only be considered in relation to a defined level of protection. A protection equivalent to an effect magnitude of 0.001-0.0001% over background incidence is generally considered acceptable. However, it is impossible to say whether this level of protection is in fact realised with the tolerable doses that are derived by employing uncertainty factors. Accordingly, it is difficult to assess whether uncertainty factors overestimate or underestimate the sensitivity differences in human populations. It is also often not appreciated that the outcome of probabilistic approaches to the multiplication of sub-factors is dependent on the choice of probability distributions. Therefore, the idea that default uncertainty factors are overly conservative worst-case scenarios which can account both for the lack of statistical power in animal experiments and protect against potential mixture effects is ill-founded. We contend that precautionary regulation should provide an

  6. Uncertainties in geologic disposal of high-level wastes - groundwater transport of radionuclides and radiological consequences

    International Nuclear Information System (INIS)

    Kocher, D.C.; Sjoreen, A.L.; Bard, C.S.

    1983-01-01

    The analysis for radionuclide transport in groundwater considers models and methods for characterizing (1) the present geologic environment and its future evolution due to natural geologic processes and to repository development and waste emplacement, (2) groundwater hydrology, (3) radionuclide geochemistry, and (4) the interactions among these phenomena. The discussion of groundwater transport focuses on the nature of the sources of uncertainty rather than on quantitative estimates of their magnitude, because of the lack of evidence that current models can provide realistic quantitative predictions of radionuclide transport in groundwater for expected repository environments. The analysis for the long-term health risk to man following releases of long-lived radionuclides to the biosphere is more quantitative and involves estimates of uncertainties in (1) radionuclide concentrations in man's exposure environment, (2) radionuclide intake by exposed individuals per unit concentration in the environment, (3) the dose per unit intake, (4) the number of exposed individuals, and (5) the health risk per unit dose. For the important long-lived radionuclides in high-level waste, uncertainties in most of the different components of a calculation of individual and collective dose per unit release appear to be no more than two or three orders of magnitude; these uncertainties are certainly much less than uncertainties in predicting groundwater transport of radionuclides between a repository and the biosphere. Several limitations in current models for predicting the health risk to man per unit release to the biosphere are discussed

  7. How risk and uncertainty is used in Supply Chain Management: a literature study

    DEFF Research Database (Denmark)

    Bøge Sørensen, Lars

    2004-01-01

    Keywords Supply Chain Management, Risk Management, Supply Chain Risk ManagementAbstract To comply with Supply Chain Management dogma companies have cut their inventoriesto a minimum, lead times have been shortened, new suppliers have been chosen and the customerportfolio has been reduced. All...... of these activities impose a great deal of risk on the firms,jeopardizing the survival of entire supply chains. In this article the author intends to investigateand document the use and meaning of Risk and Uncertainty within journals publishing material onSupply Chain Management and Logistics. Subsequently...... suggestions for further research areproposed - the integration of Risk Management into the discipline of Supply Chain Design....

  8. A dominance-based approach to map risks of ecological invasions in the presence of severe uncertainty

    Science.gov (United States)

    Denys Yemshanov; Frank H. Koch; D. Barry Lyons; Mark Ducey; Klaus Koehler

    2012-01-01

    Aim Uncertainty has been widely recognized as one of the most critical issues in predicting the expansion of ecological invasions. The uncertainty associated with the introduction and spread of invasive organisms influences how pest management decision makers respond to expanding incursions. We present a model-based approach to map risk of ecological invasions that...

  9. Incorporating uncertainties into risk assessment with an application to the exploratory studies facilities at Yucca Mountain

    International Nuclear Information System (INIS)

    Fathauer, P.M.

    1995-08-01

    A methodology that incorporates variability and reducible sources of uncertainty into the probabilistic and consequence components of risk was developed. The method was applied to the north tunnel of the Exploratory Studies Facility at Yucca Mountain in Nevada. In this assessment, variability and reducible sources of uncertainty were characterized and propagated through the risk assessment models using a Monte Carlo based software package. The results were then manipulated into risk curves at the 5% and 95% confidence levels for both the variability and overall uncertainty analyses, thus distinguishing between variability and reducible sources of uncertainty. In the Yucca Mountain application, the designation of the north tunnel as an item important to public safety, as defined by 10 CFR 60, was determined. Specifically, the annual frequency of a rock fall breaching a waste package causing an off-site dose of 500 mrem (5x10 -3 Sv) was calculated. The annual frequency, taking variability into account, ranged from 1.9x10 -9 per year at the 5% confidence level to 2.5x10 -9 per year at the 95% confidence level. The frequency range after including all uncertainty was 9.5x10 -10 to 1.8x10 -8 per year. The maximum observable frequency, at the 100% confidence level, was 4.9x10 -8 per year. This is below the 10 -6 per year frequency criteria of 10 CFR 60. Therefore, based on this work, the north tunnel does not fall under the items important to public safety designation for the event studied

  10. TREATING UNCERTAINTIES IN A NUCLEAR SEISMIC PROBABILISTIC RISK ASSESSMENT BY MEANS OF THE DEMPSTER-SHAFER THEORY OF EVIDENCE

    OpenAIRE

    Lo , Chung-Kung; Pedroni , N.; Zio , Enrico

    2014-01-01

    International audience; The analyses carried out within the Seismic Probabilistic Risk Assessments (SPRAs) of Nuclear Power Plants (NPPs) are affected by significant aleatory and epistemic uncertainties. These uncertainties have to be represented and quantified coherently with the data, information and knowledge available, to provide reasonable assurance that related decisions can be taken robustly and with confidence. The amount of data, information and knowledge available for seismic risk a...

  11. Uncertainty Quantification Reveals the Importance of Data Variability and Experimental Design Considerations for in Silico Proarrhythmia Risk Assessment

    Directory of Open Access Journals (Sweden)

    Kelly C. Chang

    2017-11-01

    Full Text Available The Comprehensive in vitro Proarrhythmia Assay (CiPA is a global initiative intended to improve drug proarrhythmia risk assessment using a new paradigm of mechanistic assays. Under the CiPA paradigm, the relative risk of drug-induced Torsade de Pointes (TdP is assessed using an in silico model of the human ventricular action potential (AP that integrates in vitro pharmacology data from multiple ion channels. Thus, modeling predictions of cardiac risk liability will depend critically on the variability in pharmacology data, and uncertainty quantification (UQ must comprise an essential component of the in silico assay. This study explores UQ methods that may be incorporated into the CiPA framework. Recently, we proposed a promising in silico TdP risk metric (qNet, which is derived from AP simulations and allows separation of a set of CiPA training compounds into Low, Intermediate, and High TdP risk categories. The purpose of this study was to use UQ to evaluate the robustness of TdP risk separation by qNet. Uncertainty in the model parameters used to describe drug binding and ionic current block was estimated using the non-parametric bootstrap method and a Bayesian inference approach. Uncertainty was then propagated through AP simulations to quantify uncertainty in qNet for each drug. UQ revealed lower uncertainty and more accurate TdP risk stratification by qNet when simulations were run at concentrations below 5× the maximum therapeutic exposure (Cmax. However, when drug effects were extrapolated above 10× Cmax, UQ showed that qNet could no longer clearly separate drugs by TdP risk. This was because for most of the pharmacology data, the amount of current block measured was <60%, preventing reliable estimation of IC50-values. The results of this study demonstrate that the accuracy of TdP risk prediction depends both on the intrinsic variability in ion channel pharmacology data as well as on experimental design considerations that preclude an

  12. Addressing uncertainties in the ERICA Integrated Approach

    International Nuclear Information System (INIS)

    Oughton, D.H.; Agueero, A.; Avila, R.; Brown, J.E.; Copplestone, D.; Gilek, M.

    2008-01-01

    Like any complex environmental problem, ecological risk assessment of the impacts of ionising radiation is confounded by uncertainty. At all stages, from problem formulation through to risk characterisation, the assessment is dependent on models, scenarios, assumptions and extrapolations. These include technical uncertainties related to the data used, conceptual uncertainties associated with models and scenarios, as well as social uncertainties such as economic impacts, the interpretation of legislation, and the acceptability of the assessment results to stakeholders. The ERICA Integrated Approach has been developed to allow an assessment of the risks of ionising radiation, and includes a number of methods that are intended to make the uncertainties and assumptions inherent in the assessment more transparent to users and stakeholders. Throughout its development, ERICA has recommended that assessors deal openly with the deeper dimensions of uncertainty and acknowledge that uncertainty is intrinsic to complex systems. Since the tool is based on a tiered approach, the approaches to dealing with uncertainty vary between the tiers, ranging from a simple, but highly conservative screening to a full probabilistic risk assessment including sensitivity analysis. This paper gives on overview of types of uncertainty that are manifest in ecological risk assessment and the ERICA Integrated Approach to dealing with some of these uncertainties

  13. Model uncertainty in safety assessment

    International Nuclear Information System (INIS)

    Pulkkinen, U.; Huovinen, T.

    1996-01-01

    The uncertainty analyses are an essential part of any risk assessment. Usually the uncertainties of reliability model parameter values are described by probability distributions and the uncertainty is propagated through the whole risk model. In addition to the parameter uncertainties, the assumptions behind the risk models may be based on insufficient experimental observations and the models themselves may not be exact descriptions of the phenomena under analysis. The description and quantification of this type of uncertainty, model uncertainty, is the topic of this report. The model uncertainty is characterized and some approaches to model and quantify it are discussed. The emphasis is on so called mixture models, which have been applied in PSAs. Some of the possible disadvantages of the mixture model are addressed. In addition to quantitative analyses, also qualitative analysis is discussed shortly. To illustrate the models, two simple case studies on failure intensity and human error modeling are described. In both examples, the analysis is based on simple mixture models, which are observed to apply in PSA analyses. (orig.) (36 refs., 6 figs., 2 tabs.)

  14. Model uncertainty in safety assessment

    Energy Technology Data Exchange (ETDEWEB)

    Pulkkinen, U; Huovinen, T [VTT Automation, Espoo (Finland). Industrial Automation

    1996-01-01

    The uncertainty analyses are an essential part of any risk assessment. Usually the uncertainties of reliability model parameter values are described by probability distributions and the uncertainty is propagated through the whole risk model. In addition to the parameter uncertainties, the assumptions behind the risk models may be based on insufficient experimental observations and the models themselves may not be exact descriptions of the phenomena under analysis. The description and quantification of this type of uncertainty, model uncertainty, is the topic of this report. The model uncertainty is characterized and some approaches to model and quantify it are discussed. The emphasis is on so called mixture models, which have been applied in PSAs. Some of the possible disadvantages of the mixture model are addressed. In addition to quantitative analyses, also qualitative analysis is discussed shortly. To illustrate the models, two simple case studies on failure intensity and human error modeling are described. In both examples, the analysis is based on simple mixture models, which are observed to apply in PSA analyses. (orig.) (36 refs., 6 figs., 2 tabs.).

  15. Framing risk and uncertainty in social science articles on climate change, 1995-2012

    NARCIS (Netherlands)

    Shaw, C.; Hellsten, I.; Nerlich, B.; Crichton, J.; Candlin, C.N.; Firkins, A.S.

    2016-01-01

    The issue of climate change is intimately linked to notions of risk and uncertainty, concepts that pose challenges to climate science, climate change communication, and science-society interactions. While a large majority of climate scientists are increasingly certain about the causes of climate

  16. Space Radiation Cancer, Circulatory Disease and CNS Risks for Near Earth Asteroid and Mars Missions: Uncertainty Estimates for Never-Smokers

    Science.gov (United States)

    Cucinotta, Francis A.; Chappell, Lori J.; Wang, Minli; Kim, Myung-Hee

    2011-01-01

    The uncertainties in estimating the health risks from galactic cosmic rays (GCR) and solar particle events (SPE) are a major limitation to the length of space missions and the evaluation of potential risk mitigation approaches. NASA limits astronaut exposures to a 3% risk of exposure induced cancer death (REID), and protects against uncertainties in risks projections using an assessment of 95% confidence intervals after propagating the error from all model factors (environment and organ exposure, risk coefficients, dose-rate modifiers, and quality factors). Because there are potentially significant late mortality risks from diseases of the circulatory system and central nervous system (CNS) which are less well defined than cancer risks, the cancer REID limit is not necessarily conservative. In this report, we discuss estimates of lifetime risks from space radiation and new estimates of model uncertainties are described. The key updates to the NASA risk projection model are: 1) Revised values for low LET risk coefficients for tissue specific cancer incidence, with incidence rates transported to an average U.S. population to estimate the probability of Risk of Exposure Induced Cancer (REIC) and REID. 2) An analysis of smoking attributable cancer risks for never-smokers that shows significantly reduced lung cancer risk as well as overall cancer risks from radiation compared to risk estimated for the average U.S. population. 3) Derivation of track structure based quality functions depends on particle fluence, charge number, Z and kinetic energy, E. 4) The assignment of a smaller maximum in quality function for leukemia than for solid cancers. 5) The use of the ICRP tissue weights is shown to over-estimate cancer risks from SPEs by a factor of 2 or more. Summing cancer risks for each tissue is recommended as a more accurate approach to estimate SPE cancer risks. 6) Additional considerations on circulatory and CNS disease risks. Our analysis shows that an individual s

  17. Financial risk management for new technology integration in energy planning under uncertainty

    International Nuclear Information System (INIS)

    Ahmed, Sajjad; Elsholkami, Mohamed; Elkamel, Ali; Du, Juan; Ydstie, Erik B.; Douglas, Peter L.

    2014-01-01

    Highlights: • Financial risk associated with over or underproduction of electricity is studied. • A two-stage stochastic model that considers parameter uncertainties is developed. • The model was applied to a real case to meet projected electricity demand of a fleet of generating stations. • Incorporation of financial risk resulted in an increase in electricity cost. • The selection of technologies was the same as that obtained from a deterministic model. - Abstract: This paper proposes a new methodology to include financial risk management in the framework of two-stage stochastic programming for energy planning under uncertainties in demand and fuel price. A deterministic mixed integer linear programming formulation is extended to a two-stage stochastic programming model in order to take into account random parameters that have discrete and finite probabilistic distributions. This was applied to a case study focusing on planning the capacity supply to meet the projected electricity demand for the fleet of electricity generation stations owned and operated by Ontario Power Generation (OPG). The objective of the proposed mathematical model is to minimize cost subject to environmental constraints. The case study is investigated by considering only existing technologies and also by considering the integration of new technologies that help achieve stricter carbon reduction requirements

  18. Distribution of uncertainties at the municipality level for flood risk modelling along the river Meuse: implications for policy-making

    Science.gov (United States)

    Pirotton, Michel; Stilmant, Frédéric; Erpicum, Sébastien; Dewals, Benjamin; Archambeau, Pierre

    2016-04-01

    Flood risk modelling has been conducted for the whole course of the river Meuse in Belgium. Major cities, such as Liege (200,000 inh.) and Namur (110,000 inh.), are located in the floodplains of river Meuse. Particular attention has been paid to uncertainty analysis and its implications for decision-making. The modelling chain contains flood frequency analysis, detailed 2D hydraulic computations, damage modelling and risk calculation. The relative importance of each source of uncertainty to the overall results uncertainty has been estimated by considering several alternate options for each step of the analysis: different distributions were considered in the flood frequency analysis; the influence of modelling assumptions and boundary conditions (e.g., steady vs. unsteady) were taken into account for the hydraulic computation; two different landuse classifications and two sets of damage functions were used; the number of exceedance probabilities involved in the risk calculation (by integration of the risk-curves) was varied. In addition, the sensitivity of the results with respect to increases in flood discharges was assessed. The considered increases are consistent with a "wet" climate change scenario for the time horizons 2021-2050 and 2071-2100 (Detrembleur et al., 2015). The results of hazard computation differ significantly between the upper and lower parts of the course of river Meuse in Belgium. In the former, inundation extents grow gradually as the considered flood discharge is increased (i.e. the exceedance probability is reduced), while in the downstream part, protection structures (mainly concrete walls) prevent inundation for flood discharges corresponding to exceedance probabilities of 0.01 and above (in the present climate). For higher discharges, large inundation extents are obtained in the floodplains. The highest values of risk (mean annual damage) are obtained in the municipalities which undergo relatively frequent flooding (upper part of the

  19. Radical uncertainty, non-predictability, antifragility and risk-sharing Islamic finance

    Directory of Open Access Journals (Sweden)

    Umar Rafi

    2016-12-01

    Full Text Available Under conditions of radical uncertainty, risk sharing renders financial systems anti-fragile. Our goal in this paper is to show that risk-sharing Islamic finance (RSIF shares the characteristics defined by Taleb for an anti-fragile system, by mapping some characteristics of anti-fragility onto those of risk-sharing Islamic finance. A key insight around which such a connection can be established is by relating the principle of “no risk-no gain”from Islamic finance to the concept of skin-in-the-game from anti-fragility theory. The relationship is then extended to other characteristics of the two frameworks, to show that RSIF overlaps with anti-fragility over many dimensions. The broader case for an antifragile system includes another important characteristic, namely “soul in the game” and concern for social justice. It is the authors’ hope that emerging research on anti-fragility, combined with the emerging research on RSIF, can have a lasting impact on the field of finance by laying the foundations for a compelling case that it is time for humanity to replace the dominant debt-based risk transfer/risk shifting financial system with a system in which everyone shares the risks faced by society. JEL: D81, D89, E44, F34, G32

  20. Uncertainties in radioecological assessment models

    International Nuclear Information System (INIS)

    Hoffman, F.O.; Miller, C.W.; Ng, Y.C.

    1983-01-01

    Environmental radiological assessments rely heavily on the use of mathematical models. The predictions of these models are inherently uncertain because models are inexact representations of real systems. The major sources of this uncertainty are related to bias in model formulation and imprecision in parameter estimation. The magnitude of uncertainty is a function of the questions asked of the model and the specific radionuclides and exposure pathways of dominant importance. It is concluded that models developed as research tools should be distinguished from models developed for assessment applications. Furthermore, increased model complexity does not necessarily guarantee increased accuracy. To improve the realism of assessment modeling, stochastic procedures are recommended that translate uncertain parameter estimates into a distribution of predicted values. These procedures also permit the importance of model parameters to be ranked according to their relative contribution to the overall predicted uncertainty. Although confidence in model predictions can be improved through site-specific parameter estimation and increased model validation, health risk factors and internal dosimetry models will probably remain important contributors to the amount of uncertainty that is irreducible. 41 references, 4 figures, 4 tables

  1. Comparison of the effect of hazard and response/fragility uncertainties on core melt probability uncertainty

    International Nuclear Information System (INIS)

    Mensing, R.W.

    1985-01-01

    This report proposes a method for comparing the effects of the uncertainty in probabilistic risk analysis (PRA) input parameters on the uncertainty in the predicted risks. The proposed method is applied to compare the effect of uncertainties in the descriptions of (1) the seismic hazard at a nuclear power plant site and (2) random variations in plant subsystem responses and component fragility on the uncertainty in the predicted probability of core melt. The PRA used is that developed by the Seismic Safety Margins Research Program

  2. Understanding and characterisation of the risks to human health from exposure to low levels of radiation

    International Nuclear Information System (INIS)

    Goodhead, D. T.

    2009-01-01

    Exposure to ionising radiation can lead to a wide variety of health effects. Cancer is judged to be the main risk from radiation at low doses and low dose rates, and controlling this risk has been the main factor in developing radiation protection practice. Conventional paradigms of radiobiology and radiation carcinogenesis have served to guide extrapolations of epidemiological data on exposed human populations, so as to estimate risks at low doses and low dose rates, to other types of ionising radiation and to non-uniform exposures. These paradigms are founded on a century of experimental and theoretical studies, but nevertheless there remain many uncertainties. Major assumptions and simplifications have been introduced to achieve a practical system of additive doses (and implied risks) for radiation protection. Advancing epidemiological studies and experimental research continue to reduce uncertainties in some areas while, in others, they raise new challenges to the generality and applicability of the conventional paradigms. (authors)

  3. What do experts stakeholders think about chemical risks and uncertainties. An Internet survey

    Energy Technology Data Exchange (ETDEWEB)

    Assmuth, T.; Lyytimaeki, J.; Hilden, M.; Lindholm, M.; Munier, B.

    2007-07-01

    This report presents results from a web-based explorative survey on integrated risk assessment. The survey was conducted in the EU-funded project NoMiracle (Novel Methods for Risk Assessment of Cumulative Stressors in Europe) which develops methods for assessing cumulative risks from combined exposures to multiple stressors. The objectives of the survey were to give a general picture of perceptions and views among experts and stakeholders concerning risks, risk assessment and risk management. The survey focused on chemicals with an emphasis on information related to complex risks and uncertainties in a management context. The methodology of the survey combined traditional multiple choice questions and a novel approach that charted the importance of different types of information in two-dimensional graphs describing simultaneously use in regulatory procedures and public discussion. Another part was linked to new methods of presenting risks and explored the ranking of separate and cumulative risks in map grids. The survey was e-mailed to 952 recipients representing researchers, national and EU level administrators, enterprises, NGOs and international organizations, and most EU member states and some other countries. The response rate (26 %) can be considered acceptable but limits the possibilities to make quantitative claims concerning the views held by different groups although it gives an overview of the types of views one encounter among experts. A key finding was the pronounced variability of concepts and views regarding risks and uncertainties, and regarding information and knowledge about these. Opinions on risks and risk assessment, particularly on integrated risk assessment, on related principles, and on the role of experts are genuinely variable. They cannot be reduced to any simple model, and cannot (and need not) be dispelled in a forced manner. The observations should be taken into account in the development and application of novel methods for risk

  4. Environmental health risk assessment and management for global climate change

    Science.gov (United States)

    Carter, P.

    2014-12-01

    This environmental health risk assessment and management approach for atmospheric greenhouse gas (GHG) pollution is based almost entirely on IPCC AR5 (2014) content, but the IPCC does not make recommendations. Large climate model uncertainties may be large environmental health risks. In accordance with environmental health risk management, we use the standard (IPCC-endorsed) formula of risk as the product of magnitude times probability, with an extremely high standard of precaution. Atmospheric GHG pollution, causing global warming, climate change and ocean acidification, is increasing as fast as ever. Time is of the essence to inform and make recommendations to governments and the public. While the 2ºC target is the only formally agreed-upon policy limit, for the most vulnerable nations, a 1.5ºC limit is being considered by the UNFCCC Secretariat. The Climate Action Network International (2014), representing civil society, recommends that the 1.5ºC limit be kept open and that emissions decline from 2015. James Hansen et al (2013) have argued that 1ºC is the danger limit. Taking into account committed global warming, its millennial duration, multiple large sources of amplifying climate feedbacks and multiple adverse impacts of global warming and climate change on crops, and population health impacts, all the IPCC AR5 scenarios carry extreme environmental health risks to large human populations and to the future of humanity as a whole. Our risk consideration finds that 2ºC carries high risks of many catastrophic impacts, that 1.5ºC carries high risks of many disastrous impacts, and that 1ºC is the danger limit. IPCC AR4 (2007) showed that emissions must be reversed by 2015 for a 2ºC warming limit. For the IPCC AR5 only the best-case scenario RCP2.6, is projected to stay under 2ºC by 2100 but the upper range is just above 2ºC. It calls for emissions to decline by 2020. We recommend that for catastrophic environmental health risk aversion, emissions decline

  5. Integrating risk analysis and multi-criteria decision support under uncertainty in electricity distribution system asset management

    International Nuclear Information System (INIS)

    Catrinu, M.D.; Nordgard, D.E.

    2011-01-01

    Asset managers in electricity distribution companies generally recognize the need and the challenge of adding structure and a higher degree of formal analysis into the increasingly complex asset management decisions. This implies improving the present asset management practice by making the best use of the available data and expert knowledge and by adopting new methods for risk analysis and decision support and nevertheless better ways to document the decisions made. This paper discusses methods for integrating risk analysis and multi-criteria decision support under uncertainty in electricity distribution system asset management. The focus is on how to include the different company objectives and risk analyses into a structured decision framework when deciding how to handle the physical assets of the electricity distribution network. This paper presents an illustrative example of decision support for maintenance and reinvestment strategies based, using expert knowledge, simplified risk analyses and multi-criteria decision analysis under uncertainty.

  6. Value at risk (VaR in uncertainty: Analysis with parametric method and black & scholes simulations

    Directory of Open Access Journals (Sweden)

    Humberto Banda Ortiz

    2014-07-01

    Full Text Available VaR is the most accepted risk measure worldwide and the leading reference in any risk management assessment. However, its methodology has important limitations which makes it unreliable in contexts of crisis or high uncertainty. For this reason, the aim of this work is to test the VaR accuracy when is employed in contexts of volatility, for which we compare the VaR outcomes in scenarios of both stability and uncertainty, using the parametric method and a historical simulation based on data generated with the Black & Scholes model. VaR main objective is the prediction of the highest expected loss for any given portfolio, but even when it is considered a useful tool for risk management under conditions of markets stability, we found that it is substantially inaccurate in contexts of crisis or high uncertainty. In addition, we found that the Black & Scholes simulations lead to underestimate the expected losses, in comparison with the parametric method and we also found that those disparities increase substantially in times of crisis. In the first section of this work we present a brief context of risk management in finance. In section II we present the existent literature relative to the VaR concept, its methods and applications. In section III we describe the methodology and assumptions used in this work. Section IV is dedicated to expose the findings. And finally, in Section V we present our conclusions.

  7. Probabilistic health risk assessment of carcinogenic emissions from a MSW gasification plant.

    Science.gov (United States)

    Lonati, Giovanni; Zanoni, Francesca

    2012-09-01

    Health risk assessment due to the atmospheric emissions of carcinogenic pollutants (PCDD/Fs and Cd) from a waste gasification plant is performed by means of a probabilistic approach based on probability density functions for the description of the input data of the model parameters involved in the assessment. These functions incorporate both the epistemic and stochastic uncertainty of the input data (namely, the emission rate of the pollutants) and of all the parameters used for individual exposure assessment through the pathways of inhalation, soil ingestion and dermal contact, and diet. The uncertainty is propagated throughout the evaluation by Monte Carlo technique, resulting in the probability distribution of the individual risk. The median risk levels nearby the plant are in the 10(-8)-10(-10) range, ten-fold lower than the deterministic estimate based on precautionary values for the input data; however, the very upper percentiles (>95th) of the risk distribution can exceed the conventional 10(-6) reference value. The estimated risk is almost entirely determined by the Cd exposure through the diet; the pathways arising from PCDD/Fs exposure are without any practical significance, suggesting that the emission control should focus on Cd in order to reduce the carcinogenic risk. Risk variance decomposition shows the prevailing influence on the estimated risk of the Cd concentration at the emission stack: thus, for a more accurate risk assessment the efforts should focus primarily on the definition of its probability density function. Copyright © 2012 Elsevier Ltd. All rights reserved.

  8. Bayesian uncertainty analyses of probabilistic risk models

    International Nuclear Information System (INIS)

    Pulkkinen, U.

    1989-01-01

    Applications of Bayesian principles to the uncertainty analyses are discussed in the paper. A short review of the most important uncertainties and their causes is provided. An application of the principle of maximum entropy to the determination of Bayesian prior distributions is described. An approach based on so called probabilistic structures is presented in order to develop a method of quantitative evaluation of modelling uncertainties. The method is applied to a small example case. Ideas for application areas for the proposed method are discussed

  9. The Health Risk Assessment of Pb and Cr leachated from fly ash monolith landfill

    International Nuclear Information System (INIS)

    Hung, Ming-Lung; Wu, Sheng-Yao; Chen, Yen-Chuan; Shih, Hsiu-Ching; Yu, Yue-Hwa; Ma, Hwong-wen

    2009-01-01

    As of 2004, nearly two hundred thousand tons of fly ash monoliths are created each year in Taiwan to confine heavy metals for reducing the leaching quantity by precipitation. However, due to abnormal monolith fracture, poorly liner quality or exceeding usage over designed landfill capacity, serious groundwater pollution of the landfills has been reported. This research focuses on Pb and Cr leaching from monolithic landfill to assess the risk of groundwater pollution in the vicinity. The methodology combines water budget simulations using HELP model with fate and risk simulations using MMSOILS model for 5 kinds of landfill structures and 2 types of leaching models, and calculates the risk distribution over 400 grids in the down gradient direction of groundwater. The results demonstrated that the worst liner quality will cause the largest risk and the most significant exposure pathway is groundwater intake, which accounted for 98% of the total risk. Comparing Pb and Cr concentrations in the groundwater with the drinking water standards, only 14.25% of the total grids are found to be under 0.05 mg/L of Pb, and over 96.5% of the total grids are in the safety range of Cr. It indicates that Pb leaching from fly ash monolithic landfills may cause serious health risks. Without consideration of the parameters uncertainty, the cancer and noncancer risk of Pb with the sanitary landfill method was 4.23E-07 and 0.63, respectively, both under acceptable levels. However, by considering the parameters uncertainty, the non-carcinogenic risk of Pb became 1.43, exceeding the acceptable level. Only under the sealed landfill method was the hazard quotient below 1. It is important to use at least the sealed landfill for fly ash monoliths containing lead to effectively reduce health risks.

  10. Estimation of Uncertainty in Risk Assessment of Hydrogen Applications

    DEFF Research Database (Denmark)

    Markert, Frank; Krymsky, V.; Kozine, Igor

    2011-01-01

    Hydrogen technologies such as hydrogen fuelled vehicles and refuelling stations are being tested in practice in a number of projects (e.g. HyFleet-Cute and Whistler project) giving valuable information on the reliability and maintenance requirements. In order to establish refuelling stations the ...... probability and the NUSAP concept to quantify uncertainties of new not fully qualified hydrogen technologies and implications to risk management.......Hydrogen technologies such as hydrogen fuelled vehicles and refuelling stations are being tested in practice in a number of projects (e.g. HyFleet-Cute and Whistler project) giving valuable information on the reliability and maintenance requirements. In order to establish refuelling stations...... the permitting authorities request qualitative and quantitative risk assessments (QRA) to show the safety and acceptability in terms of failure frequencies and respective consequences. For new technologies not all statistical data might be established or are available in good quality causing assumptions...

  11. Contaminated site risk and uncertainty assessment for impacts on surface and groundwater

    DEFF Research Database (Denmark)

    Thomsen, Nanna Isbak

    available between sites and choosing between the need for further investigation or remediation. This is a question of prioritizing the sites that pose the greatest risk, and it is a matter of making decisions under uncertainty. Both tasks require a structured assessment of the risk posed by the contaminated...... sites. In a conventional risk assessment of a contaminated site, risk is evaluated by assessing whether a concentration guideline is exceeded at a specific point of compliance in the water resource of interest. If the guideline is exceeded, it is concluded that the site poses a risk. However......, a contaminated site may pose a threat to multiple water resources, or multiple contaminated sites may threaten a single water resource. For more advanced risk assessments, it is therefore relevant to develop methods that can handle this challenge. In this thesis, four contributions are made to the field...

  12. County-Level Climate Uncertainty for Risk Assessments: Volume 10 Appendix I - Historical Evaporation.

    Energy Technology Data Exchange (ETDEWEB)

    Backus, George A.; Lowry, Thomas Stephen; Jones, Shannon M; Walker, La Tonya Nicole; Roberts, Barry L; Malczynski, Leonard A.

    2017-06-01

    This report uses the CMIP5 series of climate model simulations to produce country- level uncertainty distributions for use in socioeconomic risk assessments of climate change impacts. It provides appropriate probability distributions, by month, for 169 countries and autonomous-areas on temperature, precipitation, maximum temperature, maximum wind speed, humidity, runoff, soil moisture and evaporation for the historical period (1976-2005), and for decadal time periods to 2100. It also provides historical and future distributions for the Arctic region on ice concentration, ice thickness, age of ice, and ice ridging in 15-degree longitude arc segments from the Arctic Circle to 80 degrees latitude, plus two polar semicircular regions from 80 to 90 degrees latitude. The uncertainty is meant to describe the lack of knowledge rather than imprecision in the physical simulation because the emphasis is on unfalsified risk and its use to determine potential socioeconomic impacts. The full report is contained in 27 volumes.

  13. County-Level Climate Uncertainty for Risk Assessments: Volume 8 Appendix G - Historical Precipitation.

    Energy Technology Data Exchange (ETDEWEB)

    Backus, George A.; Lowry, Thomas Stephen; Jones, Shannon M; Walker, La Tonya Nicole; Roberts, Barry L; Malczynski, Leonard A.

    2017-06-01

    This report uses the CMIP5 series of climate model simulations to produce country- level uncertainty distributions for use in socioeconomic risk assessments of climate change impacts. It provides appropriate probability distributions, by month, for 169 countries and autonomous-areas on temperature, precipitation, maximum temperature, maximum wind speed, humidity, runoff, soil moisture and evaporation for the historical period (1976-2005), and for decadal time periods to 2100. It also provides historical and future distributions for the Arctic region on ice concentration, ice thickness, age of ice, and ice ridging in 15-degree longitude arc segments from the Arctic Circle to 80 degrees latitude, plus two polar semicircular regions from 80 to 90 degrees latitude. The uncertainty is meant to describe the lack of knowledge rather than imprecision in the physical simulation because the emphasis is on unfalsified risk and its use to determine potential socioeconomic impacts. The full report is contained in 27 volumes.

  14. Information Seeking in Uncertainty Management Theory: Exposure to Information About Medical Uncertainty and Information-Processing Orientation as Predictors of Uncertainty Management Success.

    Science.gov (United States)

    Rains, Stephen A; Tukachinsky, Riva

    2015-01-01

    Uncertainty management theory outlines the processes through which individuals cope with health-related uncertainty. Information seeking has been frequently documented as an important uncertainty management strategy. The reported study investigates exposure to specific types of medical information during a search, and one's information-processing orientation as predictors of successful uncertainty management (i.e., a reduction in the discrepancy between the level of uncertainty one feels and the level one desires). A lab study was conducted in which participants were primed to feel more or less certain about skin cancer and then were allowed to search the World Wide Web for skin cancer information. Participants' search behavior was recorded and content analyzed. The results indicate that exposure to two health communication constructs that pervade medical forms of uncertainty (i.e., severity and susceptibility) and information-processing orientation predicted uncertainty management success.

  15. An uncertainty inventory demonstration - a primary step in uncertainty quantification

    Energy Technology Data Exchange (ETDEWEB)

    Langenbrunner, James R. [Los Alamos National Laboratory; Booker, Jane M [Los Alamos National Laboratory; Hemez, Francois M [Los Alamos National Laboratory; Salazar, Issac F [Los Alamos National Laboratory; Ross, Timothy J [UNM

    2009-01-01

    Tools, methods, and theories for assessing and quantifying uncertainties vary by application. Uncertainty quantification tasks have unique desiderata and circumstances. To realistically assess uncertainty requires the engineer/scientist to specify mathematical models, the physical phenomena of interest, and the theory or framework for assessments. For example, Probabilistic Risk Assessment (PRA) specifically identifies uncertainties using probability theory, and therefore, PRA's lack formal procedures for quantifying uncertainties that are not probabilistic. The Phenomena Identification and Ranking Technique (PIRT) proceeds by ranking phenomena using scoring criteria that results in linguistic descriptors, such as importance ranked with words, 'High/Medium/Low.' The use of words allows PIRT to be flexible, but the analysis may then be difficult to combine with other uncertainty theories. We propose that a necessary step for the development of a procedure or protocol for uncertainty quantification (UQ) is the application of an Uncertainty Inventory. An Uncertainty Inventory should be considered and performed in the earliest stages of UQ.

  16. Use of health effect risk estimates and uncertainty in formal regulatory proceedings: a case study involving atmospheric particulates

    International Nuclear Information System (INIS)

    Habegger, L.J.; Oezkaynak, A.H.

    1984-01-01

    Coal combustion particulates are released to the atmosphere by power plants supplying electrical to the nuclear fuel cycle. This paper presents estimates of the public health risks associated with the release of these particulates at a rate associated with the annual nuclear fuel production requirements for a nuclear power plan. Utilization of these risk assessments as a new component in the formal evaluation of total risks from nuclear power plants is discussed. 23 references, 3 tables

  17. A scenario-based modeling approach for emergency evacuation management and risk analysis under multiple uncertainties

    Energy Technology Data Exchange (ETDEWEB)

    Lv, Y., E-mail: lvyying@hotmail.com [School of Traffic and Transportation, Beijing Jiaotong University, Beijing 100044 (China); Faculty of Engineering and Applied Science, University of Regina, Regina, Saskatchewan S4S 0A2 (Canada); Huang, G.H., E-mail: huang@iseis.org [Faculty of Engineering and Applied Science, University of Regina, Regina, Saskatchewan S4S 0A2 (Canada); Guo, L., E-mail: guoli8658@hotmail.com [Faculty of Engineering and Applied Science, University of Regina, Regina, Saskatchewan S4S 0A2 (Canada); Li, Y.P., E-mail: yongping.li@iseis.org [MOE Key Laboratory of Regional Energy and Environmental Systems Optimization, Resources and Environmental Research Academy, North China Electric Power University, Beijing 102206 (China); Dai, C., E-mail: daichao321@gmail.com [College of Environmental Sciences and Engineering, Peking University, Beijing 100871 (China); Wang, X.W., E-mail: wangxingwei0812@gamil.com [State Key Laboratory of Water Environment Simulation, School of Environment, Beijing Normal University, Beijing 100875 (China); Sun, W., E-mail: sunwei@iseis.org [Faculty of Engineering and Applied Science, University of Regina, Regina, Saskatchewan S4S 0A2 (Canada)

    2013-02-15

    Highlights: ► An interval-parameter joint-probabilistic integer programming method is developed. ► It is useful for nuclear emergency management practices under uncertainties. ► It can schedule optimal routes with maximizing evacuees during a finite time. ► Scenario-based analysis enhances robustness in controlling system risk. ► The method will help to improve the capability of disaster responses. -- Abstract: Nuclear emergency evacuation is important to prevent radioactive harms by hazardous materials and to limit the accidents’ consequences; however, uncertainties are involved in the components and processes of such a management system. In the study, an interval-parameter joint-probabilistic integer programming (IJIP) method is developed for emergency evacuation management under uncertainties. Optimization techniques of interval-parameter programming (IPP) and joint-probabilistic constrained (JPC) programming are incorporated into an integer linear programming framework, so that the approach can deal with uncertainties expressed as joint probability and interval values. The IJIP method can schedule the optimal routes to guarantee the maximum population evacuated away from the effected zone during a finite time. Furthermore, it can also facilitate post optimization analysis to enhance robustness in controlling system violation risk imposed on the joint-probabilistic constraints. The developed method has been applied to a case study of nuclear emergency management; meanwhile, a number of scenarios under different system conditions have been analyzed. It is indicated that the solutions are useful for evacuation management practices. The result of the IJIP method can not only help to raise the capability of disaster responses in a systematic manner, but also provide an insight into complex relationships among evacuation planning, resources utilizations, policy requirements and system risks.

  18. Probabilistic accident consequence uncertainty analysis -- Late health effects uncertain assessment. Volume 2: Appendices

    Energy Technology Data Exchange (ETDEWEB)

    Little, M.P.; Muirhead, C.R. [National Radiological Protection Board (United Kingdom); Goossens, L.H.J.; Kraan, B.C.P.; Cooke, R.M. [Delft Univ. of Technology (Netherlands); Harper, F.T. [Sandia National Labs., Albuquerque, NM (United States); Hora, S.C. [Univ. of Hawaii, Hilo, HI (United States)

    1997-12-01

    The development of two new probabilistic accident consequence codes, MACCS and COSYMA, was completed in 1990. These codes estimate the consequence from the accidental releases of radiological material from hypothesized accidents at nuclear installations. In 1991, the US Nuclear Regulatory Commission and the Commission of the European Communities began cosponsoring a joint uncertainty analysis of the two codes. The ultimate objective of this joint effort was to systematically develop credible and traceable uncertainty distributions for the respective code input variables. A formal expert judgment elicitation and evaluation process was identified as the best technology available for developing a library of uncertainty distributions for these consequence parameters. This report focuses on the results of the study to develop distribution for variables related to the MACCS and COSYMA late health effects models. This volume contains appendices that include (1) a summary of the MACCS and COSYMA consequence codes, (2) the elicitation questionnaires and case structures, (3) the rationales and results for the expert panel on late health effects, (4) short biographies of the experts, and (5) the aggregated results of their responses.

  19. Economic risk-based analysis: Effect of technical and market price uncertainties on the production of glycerol-based isobutanol

    DEFF Research Database (Denmark)

    Loureiro da Costa Lira Gargalo, Carina; Gernaey, Krist; Sin, Gürkan

    2016-01-01

    to propagate the market price and technical uncertainties to the economic indicator calculations and to quantify the respective economic risk. The results clearly indicated that under the given market price uncertainties, the probability of obtaining a negative NPV is 0.95. This is a very high probability...

  20. Public Health and Epidemiological Considerations For Avian Influenza Risk Mapping and Risk Assessment

    Directory of Open Access Journals (Sweden)

    Joseph P. Dudley

    2008-12-01

    Full Text Available Avian influenza viruses are now widely recognized as important threats to agricultural biosecurity and public health, and as the potential source for pandemic human influenza viruses. Human infections with avian influenza viruses have been reported from Asia (H5N1, H5N2, H9N2, Africa (H5N1, H10N7, Europe (H7N7, H7N3, H7N2, and North America (H7N3, H7N2, H11N9. Direct and indirect public health risks from avian influenzas are not restricted to the highly pathogenic H5N1 "bird flu" virus, and include low pathogenic as well as high pathogenic strains of other avian influenza virus subtypes, e.g., H1N1, H7N2, H7N3, H7N7, and H9N2. Research has shown that the 1918 Spanish Flu pandemic was caused by an H1N1 influenza virus of avian origins, and during the past decade, fatal human disease and human-to-human transmission has been confirmed among persons infected with H5N1 and H7N7 avian influenza viruses. Our ability to accurately assess and map the potential economic and public health risks associated with avian influenza outbreaks is currently constrained by uncertainties regarding key aspects of the ecology and epidemiology of avian influenza viruses in birds and humans, and the mechanisms by which highly pathogenic avian influenza viruses are transmitted between and among wild birds, domestic poultry, mammals, and humans. Key factors needing further investigation from a risk management perspective include identification of the driving forces behind the emergence and persistence of highly pathogenic avian influenza viruses within poultry populations, and a comprehensive understanding of the mechanisms regulating transmission of highly pathogenic avian influenza viruses between industrial poultry farms and backyard poultry flocks. More information is needed regarding the extent to which migratory bird populations to contribute to the transnational and transcontinental spread of highly pathogenic avian influenza viruses, and the potential for wild bird

  1. Qualitative uncertainty analysis in probabilistic safety assessment context

    International Nuclear Information System (INIS)

    Apostol, M.; Constantin, M; Turcu, I.

    2007-01-01

    In Probabilistic Safety Assessment (PSA) context, an uncertainty analysis is performed either to estimate the uncertainty in the final results (the risk to public health and safety) or to estimate the uncertainty in some intermediate quantities (the core damage frequency, the radionuclide release frequency or fatality frequency). The identification and evaluation of uncertainty are important tasks because they afford credit to the results and help in the decision-making process. Uncertainty analysis can be performed qualitatively or quantitatively. This paper performs a preliminary qualitative uncertainty analysis, by identification of major uncertainty in PSA level 1- level 2 interface and in the other two major procedural steps of a level 2 PSA i.e. the analysis of accident progression and of the containment and analysis of source term for severe accidents. One should mention that a level 2 PSA for a Nuclear Power Plant (NPP) involves the evaluation and quantification of the mechanisms, amount and probabilities of subsequent radioactive material releases from the containment. According to NUREG 1150, an important task in source term analysis is fission products transport analysis. The uncertainties related to the isotopes distribution in CANDU NPP primary circuit and isotopes' masses transferred in the containment, using SOPHAEROS module from ASTEC computer code will be also presented. (authors)

  2. Brine migration resulting from CO2 injection into saline aquifers – An approach to risk estimation including various levels of uncertainty

    DEFF Research Database (Denmark)

    Walter, Lena; Binning, Philip John; Oladyshkin, Sergey

    2012-01-01

    resulting from displaced brine. Quantifying risk on the basis of numerical simulations requires consideration of different kinds of uncertainties and this study considers both, scenario uncertainty and statistical uncertainty. Addressing scenario uncertainty involves expert opinion on relevant geological......Comprehensive risk assessment is a major task for large-scale projects such as geological storage of CO2. Basic hazards are damage to the integrity of caprocks, leakage of CO2, or reduction of groundwater quality due to intrusion of fluids. This study focuses on salinization of freshwater aquifers...... for large-scale 3D models including complex physics. Therefore, we apply a model reduction based on arbitrary polynomial chaos expansion combined with probabilistic collocation method. It is shown that, dependent on data availability, both types of uncertainty can be equally significant. The presented study...

  3. How to manage project opportunity and risk why uncertainty management can be a much better approach than risk management

    CERN Document Server

    Ward, Stephen

    2011-01-01

    Since I wrote the Foreword for the second edition of this book, risk management processes have become much more widely used, but controversy about what should be done and how best to do it has grown. Managing risk is a risky business. Chapman and Ward provide an in-depth explanation of why it is important to understand and manage underlying uncertainty in all its forms, in order to realise opportunities more fully and enhance corporate performance. They show what best practice should look like. The implications go well beyond the conventional wisdom of project risk management, providing an enl

  4. On treatment of uncertainty in system planning

    International Nuclear Information System (INIS)

    Flage, R.; Aven, T.

    2009-01-01

    In system planning and operation considerable efforts and resources are spent to reduce uncertainties, as a part of project management, uncertainty management and safety management. The basic idea seems to be that uncertainties are purely negative and should be reduced. In this paper we challenge this way of thinking, using a common industry practice as an example. In accordance with this industry practice, three uncertainty interval categories are used: ±40% intervals for the feasibility phase, ±30% intervals for the concept development phase and ±20% intervals for the engineering phase. The problem is that such a regime could easily lead to a conservative management regime encouraging the use of existing methods and tools, as new activities and novel solutions and arrangements necessarily mean increased uncertainties. In the paper we suggest an alternative approach based on uncertainty and risk descriptions, but having no predefined uncertainty reduction structures. The approach makes use of risk assessments and economic optimisation tools such as the expected net present value, but acknowledges the need for broad risk management processes which extend beyond the analyses. Different concerns need to be balanced, including economic aspects, uncertainties and risk, and practicability

  5. Water shortage risk assessment considering large-scale regional transfers: a copula-based uncertainty case study in Lunan, China.

    Science.gov (United States)

    Gao, Xueping; Liu, Yinzhu; Sun, Bowen

    2018-06-05

    The risk of water shortage caused by uncertainties, such as frequent drought, varied precipitation, multiple water resources, and different water demands, brings new challenges to the water transfer projects. Uncertainties exist for transferring water and local surface water; therefore, the relationship between them should be thoroughly studied to prevent water shortage. For more effective water management, an uncertainty-based water shortage risk assessment model (UWSRAM) is developed to study the combined effect of multiple water resources and analyze the shortage degree under uncertainty. The UWSRAM combines copula-based Monte Carlo stochastic simulation and the chance-constrained programming-stochastic multiobjective optimization model, using the Lunan water-receiving area in China as an example. Statistical copula functions are employed to estimate the joint probability of available transferring water and local surface water and sampling from the multivariate probability distribution, which are used as inputs for the optimization model. The approach reveals the distribution of water shortage and is able to emphasize the importance of improving and updating transferring water and local surface water management, and examine their combined influence on water shortage risk assessment. The possible available water and shortages can be calculated applying the UWSRAM, also with the corresponding allocation measures under different water availability levels and violating probabilities. The UWSRAM is valuable for mastering the overall multi-water resource and water shortage degree, adapting to the uncertainty surrounding water resources, establishing effective water resource planning policies for managers and achieving sustainable development.

  6. Analysis of algal bloom risk with uncertainties in lakes by integrating self-organizing map and fuzzy information theory.

    Science.gov (United States)

    Chen, Qiuwen; Rui, Han; Li, Weifeng; Zhang, Yanhui

    2014-06-01

    Algal blooms are a serious problem in waters, which damage aquatic ecosystems and threaten drinking water safety. However, the outbreak mechanism of algal blooms is very complex with great uncertainty, especially for large water bodies where environmental conditions have obvious variation in both space and time. This study developed an innovative method which integrated a self-organizing map (SOM) and fuzzy information diffusion theory to comprehensively analyze algal bloom risks with uncertainties. The Lake Taihu was taken as study case and the long-term (2004-2010) on-site monitoring data were used. The results showed that algal blooms in Taihu Lake were classified into four categories and exhibited obvious spatial-temporal patterns. The lake was mainly characterized by moderate bloom but had high uncertainty, whereas severe blooms with low uncertainty were observed in the northwest part of the lake. The study gives insight on the spatial-temporal dynamics of algal blooms, and should help government and decision-makers outline policies and practices on bloom monitoring and prevention. The developed method provides a promising approach to estimate algal bloom risks under uncertainties. Copyright © 2014 Elsevier B.V. All rights reserved.

  7. Communicating Low-Probability High-Consequence Risk, Uncertainty and Expert Confidence: Induced Seismicity of Deep Geothermal Energy and Shale Gas.

    Science.gov (United States)

    Knoblauch, Theresa A K; Stauffacher, Michael; Trutnevyte, Evelina

    2018-04-01

    Subsurface energy activities entail the risk of induced seismicity including low-probability high-consequence (LPHC) events. For designing respective risk communication, the scientific literature lacks empirical evidence of how the public reacts to different written risk communication formats about such LPHC events and to related uncertainty or expert confidence. This study presents findings from an online experiment (N = 590) that empirically tested the public's responses to risk communication about induced seismicity and to different technology frames, namely deep geothermal energy (DGE) and shale gas (between-subject design). Three incrementally different formats of written risk communication were tested: (i) qualitative, (ii) qualitative and quantitative, and (iii) qualitative and quantitative with risk comparison. Respondents found the latter two the easiest to understand, the most exact, and liked them the most. Adding uncertainty and expert confidence statements made the risk communication less clear, less easy to understand and increased concern. Above all, the technology for which risks are communicated and its acceptance mattered strongly: respondents in the shale gas condition found the identical risk communication less trustworthy and more concerning than in the DGE conditions. They also liked the risk communication overall less. For practitioners in DGE or shale gas projects, the study shows that the public would appreciate efforts in describing LPHC risks with numbers and optionally risk comparisons. However, there seems to be a trade-off between aiming for transparency by disclosing uncertainty and limited expert confidence, and thereby decreasing clarity and increasing concern in the view of the public. © 2017 Society for Risk Analysis.

  8. The Effect of Social Trust on Citizens’ Health Risk Perception in the Context of a Petrochemical Industrial Complex

    Directory of Open Access Journals (Sweden)

    Vicente Tortosa-Edo

    2013-01-01

    Full Text Available Perceived risk of environmental threats often translates into psychological stress with a wide range of effects on health and well-being. Petrochemical industrial complexes constitute one of the sites that can cause considerable pollution and health problems. The uncertainty around emissions results in a perception of risk for citizens residing in neighboring areas, which translates into anxiety and physiological stress. In this context, social trust is a key factor in managing the perceived risk. In the case of industrial risks, it is essential to distinguish between trust in the companies that make up the industry, and trust in public institutions. In the context of a petrochemical industrial complex located in the port of Castellón (Spain, this paper primarily discusses how trust — both in the companies located in the petrochemical complex and in the public institutions — affects citizens’ health risk perception. The research findings confirm that while the trust in companies negatively affects citizens’ health risk perception, trust in public institutions does not exert a direct and significant effect. Analysis also revealed that trust in public institutions and health risk perception are essentially linked indirectly (through trust in companies.

  9. The Effect of Social Trust on Citizens’ Health Risk Perception in the Context of a Petrochemical Industrial Complex

    Science.gov (United States)

    López-Navarro, Miguel Ángel; Llorens-Monzonís, Jaume; Tortosa-Edo, Vicente

    2013-01-01

    Perceived risk of environmental threats often translates into psychological stress with a wide range of effects on health and well-being. Petrochemical industrial complexes constitute one of the sites that can cause considerable pollution and health problems. The uncertainty around emissions results in a perception of risk for citizens residing in neighboring areas, which translates into anxiety and physiological stress. In this context, social trust is a key factor in managing the perceived risk. In the case of industrial risks, it is essential to distinguish between trust in the companies that make up the industry, and trust in public institutions. In the context of a petrochemical industrial complex located in the port of Castellón (Spain), this paper primarily discusses how trust—both in the companies located in the petrochemical complex and in the public institutions—affects citizens’ health risk perception. The research findings confirm that while the trust in companies negatively affects citizens’ health risk perception, trust in public institutions does not exert a direct and significant effect. Analysis also revealed that trust in public institutions and health risk perception are essentially linked indirectly (through trust in companies). PMID:23337129

  10. Disruptive event uncertainties in a perturbation approach to nuclear waste repository risk analysis

    Energy Technology Data Exchange (ETDEWEB)

    Harvey, T.F.

    1980-09-01

    A methodology is developed for incorporating a full range of the principal forecasting uncertainties into a risk analysis of a nuclear waste repository. The result of this methodology is a set of risk curves similar to those used by Rasmussen in WASH-1400. The set of curves is partially derived from a perturbation approach to analyze potential disruptive event sequences. Such a scheme could be useful in truncating the number of disruptive event scenarios and providing guidance to those establishing data-base development priorities.

  11. Risk-based flood protection planning under climate change and modeling uncertainty: a pre-alpine case study

    Directory of Open Access Journals (Sweden)

    B. Dittes

    2018-05-01

    Full Text Available Planning authorities are faced with a range of questions when planning flood protection measures: is the existing protection adequate for current and future demands or should it be extended? How will flood patterns change in the future? How should the uncertainty pertaining to this influence the planning decision, e.g., for delaying planning or including a safety margin? Is it sufficient to follow a protection criterion (e.g., to protect from the 100-year flood or should the planning be conducted in a risk-based way? How important is it for flood protection planning to accurately estimate flood frequency (changes, costs and damage? These are questions that we address for a medium-sized pre-alpine catchment in southern Germany, using a sequential Bayesian decision making framework that quantitatively addresses the full spectrum of uncertainty. We evaluate different flood protection systems considered by local agencies in a test study catchment. Despite large uncertainties in damage, cost and climate, the recommendation is robust for the most conservative approach. This demonstrates the feasibility of making robust decisions under large uncertainty. Furthermore, by comparison to a previous study, it highlights the benefits of risk-based planning over the planning of flood protection to a prescribed return period.

  12. Risk-based flood protection planning under climate change and modeling uncertainty: a pre-alpine case study

    Science.gov (United States)

    Dittes, Beatrice; Kaiser, Maria; Špačková, Olga; Rieger, Wolfgang; Disse, Markus; Straub, Daniel

    2018-05-01

    Planning authorities are faced with a range of questions when planning flood protection measures: is the existing protection adequate for current and future demands or should it be extended? How will flood patterns change in the future? How should the uncertainty pertaining to this influence the planning decision, e.g., for delaying planning or including a safety margin? Is it sufficient to follow a protection criterion (e.g., to protect from the 100-year flood) or should the planning be conducted in a risk-based way? How important is it for flood protection planning to accurately estimate flood frequency (changes), costs and damage? These are questions that we address for a medium-sized pre-alpine catchment in southern Germany, using a sequential Bayesian decision making framework that quantitatively addresses the full spectrum of uncertainty. We evaluate different flood protection systems considered by local agencies in a test study catchment. Despite large uncertainties in damage, cost and climate, the recommendation is robust for the most conservative approach. This demonstrates the feasibility of making robust decisions under large uncertainty. Furthermore, by comparison to a previous study, it highlights the benefits of risk-based planning over the planning of flood protection to a prescribed return period.

  13. Assessing the near-term risk of climate uncertainty : interdependencies among the U.S. states.

    Energy Technology Data Exchange (ETDEWEB)

    Loose, Verne W.; Lowry, Thomas Stephen; Malczynski, Leonard A.; Tidwell, Vincent Carroll; Stamber, Kevin Louis; Reinert, Rhonda K.; Backus, George A.; Warren, Drake E.; Zagonel, Aldo A.; Ehlen, Mark Andrew; Klise, Geoffrey T.; Vargas, Vanessa N.

    2010-04-01

    Policy makers will most likely need to make decisions about climate policy before climate scientists have resolved all relevant uncertainties about the impacts of climate change. This study demonstrates a risk-assessment methodology for evaluating uncertain future climatic conditions. We estimate the impacts of climate change on U.S. state- and national-level economic activity from 2010 to 2050. To understand the implications of uncertainty on risk and to provide a near-term rationale for policy interventions to mitigate the course of climate change, we focus on precipitation, one of the most uncertain aspects of future climate change. We use results of the climate-model ensemble from the Intergovernmental Panel on Climate Change's (IPCC) Fourth Assessment Report 4 (AR4) as a proxy for representing climate uncertainty over the next 40 years, map the simulated weather from the climate models hydrologically to the county level to determine the physical consequences on economic activity at the state level, and perform a detailed 70-industry analysis of economic impacts among the interacting lower-48 states. We determine the industry-level contribution to the gross domestic product and employment impacts at the state level, as well as interstate population migration, effects on personal income, and consequences for the U.S. trade balance. We show that the mean or average risk of damage to the U.S. economy from climate change, at the national level, is on the order of $1 trillion over the next 40 years, with losses in employment equivalent to nearly 7 million full-time jobs.

  14. Influence of air quality model resolution on uncertainty associated with health impacts

    Directory of Open Access Journals (Sweden)

    T. M. Thompson

    2012-10-01

    Full Text Available We use regional air quality modeling to evaluate the impact of model resolution on uncertainty associated with the human health benefits resulting from proposed air quality regulations. Using a regional photochemical model (CAMx, we ran a modeling episode with meteorological inputs simulating conditions as they occurred during August through September 2006 (a period representative of conditions leading to high ozone, and two emissions inventories (a 2006 base case and a 2018 proposed control scenario, both for Houston, Texas at 36, 12, 4 and 2 km resolution. The base case model performance was evaluated for each resolution against daily maximum 8-h averaged ozone measured at monitoring stations. Results from each resolution were more similar to each other than they were to measured values. Population-weighted ozone concentrations were calculated for each resolution and applied to concentration response functions (with 95% confidence intervals to estimate the health impacts of modeled ozone reduction from the base case to the control scenario. We found that estimated avoided mortalities were not significantly different between the 2, 4 and 12 km resolution runs, but the 36 km resolution may over-predict some potential health impacts. Given the cost/benefit analysis requirements motivated by Executive Order 12866 as it applies to the Clean Air Act, the uncertainty associated with human health impacts and therefore the results reported in this study, we conclude that health impacts calculated from population weighted ozone concentrations obtained using regional photochemical models at 36 km resolution fall within the range of values obtained using fine (12 km or finer resolution modeling. However, in some cases, 36 km resolution may not be fine enough to statistically replicate the results achieved using 2, 4 or 12 km resolution. On average, when modeling at 36 km resolution, an estimated 5 deaths per week during the May through September ozone

  15. Probabilistic risk analysis and fault trees: Initial discussion of application to identification of risk at a wellhead

    Science.gov (United States)

    Rodak, C.; Silliman, S.

    2012-02-01

    Wellhead protection is of critical importance for managing groundwater resources. While a number of previous authors have addressed questions related to uncertainties in advective capture zones, methods for addressing wellhead protection in the presence of uncertainty in the chemistry of groundwater contaminants, the relationship between land-use and contaminant sources, and the impact on health of the receiving population are limited. It is herein suggested that probabilistic risk analysis (PRA) combined with fault trees (FT) provides a structure whereby chemical transport can be combined with uncertainties in source, chemistry, and health impact to assess the probability of negative health outcomes in the population. As such, PRA-FT provides a new strategy for the identification of areas of probabilistically high human health risk. Application of this approach is demonstrated through a simplified case study involving flow to a well in an unconfined aquifer with heterogeneity in aquifer properties and contaminant sources.

  16. Accounting for parameter uncertainty in the definition of parametric distributions used to describe individual patient variation in health economic models

    Directory of Open Access Journals (Sweden)

    Koen Degeling

    2017-12-01

    Full Text Available Abstract Background Parametric distributions based on individual patient data can be used to represent both stochastic and parameter uncertainty. Although general guidance is available on how parameter uncertainty should be accounted for in probabilistic sensitivity analysis, there is no comprehensive guidance on reflecting parameter uncertainty in the (correlated parameters of distributions used to represent stochastic uncertainty in patient-level models. This study aims to provide this guidance by proposing appropriate methods and illustrating the impact of this uncertainty on modeling outcomes. Methods Two approaches, 1 using non-parametric bootstrapping and 2 using multivariate Normal distributions, were applied in a simulation and case study. The approaches were compared based on point-estimates and distributions of time-to-event and health economic outcomes. To assess sample size impact on the uncertainty in these outcomes, sample size was varied in the simulation study and subgroup analyses were performed for the case-study. Results Accounting for parameter uncertainty in distributions that reflect stochastic uncertainty substantially increased the uncertainty surrounding health economic outcomes, illustrated by larger confidence ellipses surrounding the cost-effectiveness point-estimates and different cost-effectiveness acceptability curves. Although both approaches performed similar for larger sample sizes (i.e. n = 500, the second approach was more sensitive to extreme values for small sample sizes (i.e. n = 25, yielding infeasible modeling outcomes. Conclusions Modelers should be aware that parameter uncertainty in distributions used to describe stochastic uncertainty needs to be reflected in probabilistic sensitivity analysis, as it could substantially impact the total amount of uncertainty surrounding health economic outcomes. If feasible, the bootstrap approach is recommended to account for this uncertainty.

  17. Accounting for parameter uncertainty in the definition of parametric distributions used to describe individual patient variation in health economic models.

    Science.gov (United States)

    Degeling, Koen; IJzerman, Maarten J; Koopman, Miriam; Koffijberg, Hendrik

    2017-12-15

    Parametric distributions based on individual patient data can be used to represent both stochastic and parameter uncertainty. Although general guidance is available on how parameter uncertainty should be accounted for in probabilistic sensitivity analysis, there is no comprehensive guidance on reflecting parameter uncertainty in the (correlated) parameters of distributions used to represent stochastic uncertainty in patient-level models. This study aims to provide this guidance by proposing appropriate methods and illustrating the impact of this uncertainty on modeling outcomes. Two approaches, 1) using non-parametric bootstrapping and 2) using multivariate Normal distributions, were applied in a simulation and case study. The approaches were compared based on point-estimates and distributions of time-to-event and health economic outcomes. To assess sample size impact on the uncertainty in these outcomes, sample size was varied in the simulation study and subgroup analyses were performed for the case-study. Accounting for parameter uncertainty in distributions that reflect stochastic uncertainty substantially increased the uncertainty surrounding health economic outcomes, illustrated by larger confidence ellipses surrounding the cost-effectiveness point-estimates and different cost-effectiveness acceptability curves. Although both approaches performed similar for larger sample sizes (i.e. n = 500), the second approach was more sensitive to extreme values for small sample sizes (i.e. n = 25), yielding infeasible modeling outcomes. Modelers should be aware that parameter uncertainty in distributions used to describe stochastic uncertainty needs to be reflected in probabilistic sensitivity analysis, as it could substantially impact the total amount of uncertainty surrounding health economic outcomes. If feasible, the bootstrap approach is recommended to account for this uncertainty.

  18. Human health risk assessment methodology for the UMTRA Ground Water Project

    International Nuclear Information System (INIS)

    1994-11-01

    This document presents the method used to evaluate human risks associated with ground water contamination at inactive uranium processing sites. The intent of these evaluations is to provide the public and remedial action decision-makers with information about the health risks that might be expected at each site in a manner that is easily understood. The method (1) develops probabilistic distributions for exposure variables where sufficient data exist, (2) simulates predicted exposure distributions using Monte Carlo techniques, and (3) develops toxicity ranges that reflect human data when available, animal data if human data are insufficient, regulatory levels, and uncertainties. Risk interpretation is based on comparison of the potential exposure distributions with the derived toxicity ranges. Graphic presentations are an essential element of the semiquantitative interpretation and are expected to increase understanding by the public and decision-makers

  19. The costs of uncertainty: regulating health and safety in the Canadian uranium industry

    International Nuclear Information System (INIS)

    Robinson, I.

    1982-04-01

    Federalism, and particularly federal/provincial jurisdictional relationships, have led to considerable uncertainty in the regulation of occupational health and safety and of environmental protection in the Canadian uranium mining industry. The two principal uranium producing provinces in Canada are Saskatchewan and Ontario. Since 1978, in an attempt to avoid constitutional issues, both these provinces and the federal government as well have proceeded unilaterally with health and safety reforms for the industry. In Saskatchewan this has resulted in areas of overlapping jurisdiction, which have led to uncertainty over the legal enforceability of the provincial regulations. In Ontario, the province has left significant gaps in the protection of both workers and the environment. Little progress can be expected in eliminating these gaps and overlaps until the current administrative and jurisdictional arrangements are understood

  20. Human health risk assessment screening approach for evaluating contaminants at source control and integrator operable units

    International Nuclear Information System (INIS)

    Blaylock, B.G.; Frank, M.L.; Hoffman, F.O.; Miller, P.D.; White, R.K.; Purucker, S.T.; Redfearn, A.

    1992-10-01

    A more streamlined approach is proposed for executing the Remedial Investigation/Feasibility Study Process. This approach recognizes the uncertainties associated with the process, particularly regarding the derivation of human health risk estimates. The approach is tailored for early identification of sites and contaminants of immediate concern, early remediation of such sites, and early identification of low-risk sites that can be eliminated from further investigations. The purpose is to hasten the clean-up process and do so in a cost-effective manner

  1. Optimizing an Investment Solution in Conditions of Uncertainty and Risk as a Multicriterial Task

    Directory of Open Access Journals (Sweden)

    Kotsyuba Oleksiy S.

    2017-10-01

    Full Text Available The article is concerned with the methodology for optimizing investment decisions in conditions of uncertainty and risk. The subject area of the study relates, first of all, to real investment. The problem of modeling an optimal investment solution is considered to be a multicriterial task. Also, the constructive part of the publication is based on the position that the multicriteriality of objectives of investment projecting is the result, first, of the complex nature of the category of economic attractiveness (efficiency of real investment, and secondly, of the need to take into account the risk factor, which is a vector measure, in the preparation of an investment solution. An attempt has been made to develop an instrumentarium to optimize investment decisions in a situation of uncertainty and the risk it engenders, based on the use of roll-up of the local criteria. As a result of its implementation, a model has been proposed, which has the advantage that it takes into account, to a greater extent than is the case for standardized roll-up options, the contensive and formal features of the local (detailed criteria.

  2. County-Level Climate Uncertainty for Risk Assessments: Volume 17 Appendix P - Forecast Soil Moisture

    Energy Technology Data Exchange (ETDEWEB)

    Backus, George A.; Lowry, Thomas Stephen; Jones, Shannon M; Walker, La Tonya Nicole; Roberts, Barry L; Malczynski, Leonard A.

    2017-04-01

    This report uses the CMIP5 series of climate model simulations to produce country- level uncertainty distributions for use in socioeconomic risk assessments of climate change impacts. It provides appropriate probability distributions, by month, for 169 countries and autonomous-areas on temperature, precipitation, maximum temperature, maximum wind speed, humidity, runoff, soil moisture and evaporation for the historical period (1976-2005), and for decadal time periods to 2100. It also provides historical and future distributions for the Arctic region on ice concentration, ice thickness, age of ice, and ice ridging in 15-degree longitude arc segments from the Arctic Circle to 80 degrees latitude, plus two polar semicircular regions from 80 to 90 degrees latitude. The uncertainty is meant to describe the lack of knowledge rather than imprecision in the physical simulation because the emphasis is on unfalsified risk and its use to determine potential socioeconomic impacts. The full report is contained in 27 volumes.

  3. County-Level Climate Uncertainty for Risk Assessments: Volume 26 Appendix Y - Historical Ridging Rate.

    Energy Technology Data Exchange (ETDEWEB)

    Backus, George A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Lowry, Thomas Stephen [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Jones, Shannon M. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Walker, La Tonya Nicole [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Roberts, Barry L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Malczynski, Leonard A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-05-01

    This report uses the CMIP5 series of climate model simulations to produce country- level uncertainty distributions for use in socioeconomic risk assessments of climate change impacts. It provides appropriate probability distributions, by month, for 169 countries and autonomous-areas on temperature, precipitation, maximum temperature, maximum wind speed, humidity, runoff, soil moisture and evaporation for the historical period (1976-2005), and for decadal time periods to 2100. It also provides historical and future distributions for the Arctic region on ice concentration, ice thickness, age of ice, and ice ridging in 15-degree longitude arc segments from the Arctic Circle to 80 degrees latitude, plus two polar semicircular regions from 80 to 90 degrees latitude. The uncertainty is meant to describe the lack of knowledge rather than imprecision in the physical simulation because the emphasis is on unfalsified risk and its use to determine potential socioeconomic impacts. The full report is contained in 27 volumes.

  4. County-Level Climate Uncertainty for Risk Assessments: Volume 27 Appendix Z - Forecast Ridging Rate.

    Energy Technology Data Exchange (ETDEWEB)

    Backus, George A.; Lowry, Thomas Stephen; Jones, Shannon M; Walker, La Tonya Nicole; Roberts, Barry L; Malczynski, Leonard A.

    2017-06-01

    This report uses the CMIP5 series of climate model simulations to produce country- level uncertainty distributions for use in socioeconomic risk assessments of climate change impacts. It provides appropriate probability distributions, by month, for 169 countries and autonomous-areas on temperature, precipitation, maximum temperature, maximum wind speed, humidity, runoff, soil moisture and evaporation for the historical period (1976-2005), and for decadal time periods to 2100. It also provides historical and future distributions for the Arctic region on ice concentration, ice thickness, age of ice, and ice ridging in 15-degree longitude arc segments from the Arctic Circle to 80 degrees latitude, plus two polar semicircular regions from 80 to 90 degrees latitude. The uncertainty is meant to describe the lack of knowledge rather than imprecision in the physical simulation because the emphasis is on unfalsified risk and its use to determine potential socioeconomic impacts. The full report is contained in 27 volumes.

  5. County-Level Climate Uncertainty for Risk Assessments: Volume 14 Appendix M - Historical Surface Runoff.

    Energy Technology Data Exchange (ETDEWEB)

    Backus, George A.; Lowry, Thomas Stephen; Jones, Shannon M; Walker, La Tonya Nicole; Roberts, Barry L; Malczynski, Leonard A.

    2017-06-01

    This report uses the CMIP5 series of climate model simulations to produce country- level uncertainty distributions for use in socioeconomic risk assessments of climate change impacts. It provides appropriate probability distributions, by month, for 169 countries and autonomous-areas on temperature, precipitation, maximum temperature, maximum wind speed, humidity, runoff, soil moisture and evaporation for the historical period (1976-2005), and for decadal time periods to 2100. It also provides historical and future distributions for the Arctic region on ice concentration, ice thickness, age of ice, and ice ridging in 15-degree longitude arc segments from the Arctic Circle to 80 degrees latitude, plus two polar semicircular regions from 80 to 90 degrees latitude. The uncertainty is meant to describe the lack of knowledge rather than imprecision in the physical simulation because the emphasis is on unfalsified risk and its use to determine potential socioeconomic impacts. The full report is contained in 27 volumes.

  6. County-Level Climate Uncertainty for Risk Assessments: Volume 12 Appendix K - Historical Rel. Humidity.

    Energy Technology Data Exchange (ETDEWEB)

    Backus, George A.; Lowry, Thomas Stephen; Jones, Shannon M; Walker, La Tonya Nicole; Roberts, Barry L; Malczynski, Leonard A.

    2017-06-01

    This report uses the CMIP5 series of climate model simulations to produce country- level uncertainty distributions for use in socioeconomic risk assessments of climate change impacts. It provides appropriate probability distributions, by month, for 169 countries and autonomous-areas on temperature, precipitation, maximum temperature, maximum wind speed, humidity, runoff, soil moisture and evaporation for the historical period (1976-2005), and for decadal time periods to 2100. It also provides historical and future distributions for the Arctic region on ice concentration, ice thickness, age of ice, and ice ridging in 15-degree longitude arc segments from the Arctic Circle to 80 degrees latitude, plus two polar semicircular regions from 80 to 90 degrees latitude. The uncertainty is meant to describe the lack of knowledge rather than imprecision in the physical simulation because the emphasis is on unfalsified risk and its use to determine potential socioeconomic impacts. The full report is contained in 27 volumes.

  7. County-Level Climate Uncertainty for Risk Assessments: Volume 16 Appendix O - Historical Soil Moisture.

    Energy Technology Data Exchange (ETDEWEB)

    Backus, George A.; Lowry, Thomas Stephen; Jones, Shannon M; Walker, La Tonya Nicole; Roberts, Barry L; Malczynski, Leonard A.

    2017-06-01

    This report uses the CMIP5 series of climate model simulations to produce country- level uncertainty distributions for use in socioeconomic risk assessments of climate change impacts. It provides appropriate probability distributions, by month, for 169 countries and autonomous-areas on temperature, precipitation, maximum temperature, maximum wind speed, humidity, runoff, soil moisture and evaporation for the historical period (1976-2005), and for decadal time periods to 2100. It also provides historical and future distributions for the Arctic region on ice concentration, ice thickness, age of ice, and ice ridging in 15-degree longitude arc segments from the Arctic Circle to 80 degrees latitude, plus two polar semicircular regions from 80 to 90 degrees latitude. The uncertainty is meant to describe the lack of knowledge rather than imprecision in the physical simulation because the emphasis is on unfalsified risk and its use to determine potential socioeconomic impacts. The full report is contained in 27 volumes.

  8. County-Level Climate Uncertainty for Risk Assessments: Volume 15 Appendix N - Forecast Surface Runoff.

    Energy Technology Data Exchange (ETDEWEB)

    Backus, George A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Lowry, Thomas Stephen [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Jones, Shannon M. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Walker, La Tonya Nicole [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Roberts, Barry L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Malczynski, Leonard A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-05-01

    This report uses the CMIP5 series of climate model simulations to produce country- level uncertainty distributions for use in socioeconomic risk assessments of climate change impacts. It provides appropriate probability distributions, by month, for 169 countries and autonomous-areas on temperature, precipitation, maximum temperature, maximum wind speed, humidity, runoff, soil moisture and evaporation for the historical period (1976-2005), and for decadal time periods to 2100. It also provides historical and future distributions for the Arctic region on ice concentration, ice thickness, age of ice, and ice ridging in 15-degree longitude arc segments from the Arctic Circle to 80 degrees latitude, plus two polar semicircular regions from 80 to 90 degrees latitude. The uncertainty is meant to describe the lack of knowledge rather than imprecision in the physical simulation because the emphasis is on unfalsified risk and its use to determine potential socioeconomic impacts. The full report is contained in 27 volumes.

  9. Blockchain to Rule the Waves - Nascent Design Principles for Reducing Risk and Uncertainty in Decentralized Environments

    DEFF Research Database (Denmark)

    Nærland, Kristoffer; Müller-Bloch, Christoph; Beck, Roman

    2017-01-01

    Many decentralized, inter-organizational environments such as supply chains are characterized by high transactional uncertainty and risk. At the same time, blockchain technology promises to mitigate these issues by introducing certainty into economic transactions. This paper discusses the findings...... of a Design Science Research project involving the construction and evaluation of an information technology artifact in collaboration with Maersk, a leading international shipping company, where central documents in shipping, such as the Bill of Lading, are turned into a smart contract on blockchain. Based...... on our insights from the project, we provide first evidence for preliminary design principles for applications that aim to mitigate the transactional risk and uncertainty in decentralized environments using blockchain. Both the artifact and the first evidence for emerging design principles are novel...

  10. Frequency and prioritization of patient health risks from a structured health risk assessment.

    Science.gov (United States)

    Phillips, Siobhan M; Glasgow, Russell E; Bello, Ghalib; Ory, Marcia G; Glenn, Beth A; Sheinfeld-Gorin, Sherri N; Sabo, Roy T; Heurtin-Roberts, Suzanne; Johnson, Sallie Beth; Krist, Alex H

    2014-01-01

    To describe the frequency and patient-reported readiness to change, desire to discuss, and perceived importance of 13 health risk factors in a diverse range of primary care practices. Patients (n = 1,707) in 9 primary care practices in the My Own Health Report (MOHR) trial reported general, behavioral, and psychosocial risk factors (body mass index [BMI], health status, diet, physical activity, sleep, drug use, stress, anxiety or worry, and depression). We classified responses as "at risk" or "healthy" for each factor, and patients indicated their readiness to change and/or desire to discuss identified risk factors with providers. Patients also selected 1 of the factors they were ready to change as most important. We then calculated frequencies within and across these factors and examined variation by patient characteristics and across practices. On average, patients had 5.8 (SD = 2.12; range, 0-13) unhealthy behaviors and mental health risk factors. About 55% of patients had more than 6 risk factors. On average, patients wanted to change 1.2 and discuss 0.7 risks. The most common risks were inadequate fruit/vegetable consumption (84.5%) and overweight/obesity (79.6%). Patients were most ready to change BMI (33.3%) and depression (30.7%), and most wanted to discuss depression (41.9%) and anxiety or worry (35.2%). Overall, patients rated health status as most important. Implementing routine comprehensive health risk assessments in primary care will likely identify a high number of behavioral and psychosocial health risks. By soliciting patient priorities, providers and patients can better manage counseling and behavior change. © 2014 Annals of Family Medicine, Inc.

  11. Assessment of uncertainties in risk analysis of chemical establishments. The ASSURANCE project. Final summary report

    DEFF Research Database (Denmark)

    Lauridsen, K.; Kozine, Igor; Markert, Frank

    2002-01-01

    and led the comparison of results in order to reveal the causes for differences between the partners' results. The results of the project point to an increased awareness of the potential uncertainties in riskanalyses and highlight a number of important sources of such uncertainties. In the hazard......This report summarises the results obtained in the ASSURANCE project (EU contract number ENV4-CT97-0627). Seven teams have performed risk analyses for the same chemical facility, an ammonia storage. The EC's Joint Research Centre at Ispra and RisøNational Laboratory co-ordinated the exercise...

  12. Treating Uncertainties in A Nuclear Seismic Probabilistic Risk Assessment by Means of the Distemper-Safer Theory of Evidence

    International Nuclear Information System (INIS)

    Lo, Chungkung; Pedroni, N.; Zio, E.

    2014-01-01

    The analyses carried out within the Seismic Probabilistic Risk Assessments (SPRAs) of Nuclear Power Plants (NPPs) are affected by significant aleatory and epistemic uncertainties. These uncertainties have to be represented and quantified coherently with the data, information and knowledge available, to provide reasonable assurance that related decisions can be taken robustly and with confidence. The amount of data, information and knowledge available for seismic risk assessment is typically limited, so that the analysis must strongly rely on expert judgments. In this paper, a Dempster-Shafer Theory (DST) framework for handling uncertainties in NPP SPRAs is proposed and applied to an example case study. The main contributions of this paper are two: (i) applying the complete DST framework to SPRA models, showing how to build the Dempster-Shafer structures of the uncertainty parameters based on industry generic data, and (ii) embedding Bayesian updating based on plant specific data into the framework. The results of the application to a case study show that the approach is feasible and effective in (i) describing and jointly propagating aleatory and epistemic uncertainties in SPRA models and (ii) providing 'conservative' bounds on the safety quantities of interest (i. e. Core Damage Frequency, CDF) that reflect the (limited) state of knowledge of the experts about the system of interest

  13. Treating Uncertainties in A Nuclear Seismic Probabilistic Risk Assessment by Means of the Distemper-Safer Theory of Evidence

    Energy Technology Data Exchange (ETDEWEB)

    Lo, Chungkung [Chair on Systems Science and the Energetic Challenge, Paris (France); Pedroni, N.; Zio, E. [Politecnico di Milano, Milano (Italy)

    2014-02-15

    The analyses carried out within the Seismic Probabilistic Risk Assessments (SPRAs) of Nuclear Power Plants (NPPs) are affected by significant aleatory and epistemic uncertainties. These uncertainties have to be represented and quantified coherently with the data, information and knowledge available, to provide reasonable assurance that related decisions can be taken robustly and with confidence. The amount of data, information and knowledge available for seismic risk assessment is typically limited, so that the analysis must strongly rely on expert judgments. In this paper, a Dempster-Shafer Theory (DST) framework for handling uncertainties in NPP SPRAs is proposed and applied to an example case study. The main contributions of this paper are two: (i) applying the complete DST framework to SPRA models, showing how to build the Dempster-Shafer structures of the uncertainty parameters based on industry generic data, and (ii) embedding Bayesian updating based on plant specific data into the framework. The results of the application to a case study show that the approach is feasible and effective in (i) describing and jointly propagating aleatory and epistemic uncertainties in SPRA models and (ii) providing 'conservative' bounds on the safety quantities of interest (i. e. Core Damage Frequency, CDF) that reflect the (limited) state of knowledge of the experts about the system of interest.

  14. Exploration Health Risks: Probabilistic Risk Assessment

    Science.gov (United States)

    Rhatigan, Jennifer; Charles, John; Hayes, Judith; Wren, Kiley

    2006-01-01

    Maintenance of human health on long-duration exploration missions is a primary challenge to mission designers. Indeed, human health risks are currently the largest risk contributors to the risks of evacuation or loss of the crew on long-duration International Space Station missions. We describe a quantitative assessment of the relative probabilities of occurrence of the individual risks to human safety and efficiency during space flight to augment qualitative assessments used in this field to date. Quantitative probabilistic risk assessments will allow program managers to focus resources on those human health risks most likely to occur with undesirable consequences. Truly quantitative assessments are common, even expected, in the engineering and actuarial spheres, but that capability is just emerging in some arenas of life sciences research, such as identifying and minimize the hazards to astronauts during future space exploration missions. Our expectation is that these results can be used to inform NASA mission design trade studies in the near future with the objective of preventing the higher among the human health risks. We identify and discuss statistical techniques to provide this risk quantification based on relevant sets of astronaut biomedical data from short and long duration space flights as well as relevant analog populations. We outline critical assumptions made in the calculations and discuss the rationale for these. Our efforts to date have focussed on quantifying the probabilities of medical risks that are qualitatively perceived as relatively high risks of radiation sickness, cardiac dysrhythmias, medically significant renal stone formation due to increased calcium mobilization, decompression sickness as a result of EVA (extravehicular activity), and bone fracture due to loss of bone mineral density. We present these quantitative probabilities in order-of-magnitude comparison format so that relative risk can be gauged. We address the effects of

  15. Inexact stochastic risk-aversion optimal day-ahead dispatch model for electricity system management with wind power under uncertainty

    International Nuclear Information System (INIS)

    Ji, Ling; Huang, Guo-He; Huang, Lu-Cheng; Xie, Yu-Lei; Niu, Dong-Xiao

    2016-01-01

    High penetration of wind power generation and deregulated electricity market brings a great challenge to the electricity system operators. It is crucial to make optimal strategy among various generation units and spinning reserve for supporting the system safety operation. By integrating interval two-stage programming and stochastic robust programming, this paper proposes a novel robust model for day-ahead dispatch and risk-aversion management under uncertainties. In the proposed model, the uncertainties are expressed as interval values with different scenario probability. The proposed method requires low computation, and still retains the complete information. A case study is to validate the effectiveness of this approach. Facing the uncertainties of future demand and electricity price, the system operators need to make optimal dispatch strategy for thermal power units and wind turbine, and arrange proper spinning reserve and flexible demand response program to mitigate wind power forecasting error. The optimal strategies provide the system operators with better trade-off between the maximum benefits and the minimum system risk. In additional, two different market rules are compared. The results show that extra financial penalty for the wind power dispatch deviation is another efficient way to enhance the risk consciousness of decision makers and lead to more conservative strategy. - Highlights: • An inexact two-stage stochastic robust programming model for electricity system with wind power penetration. • Uncertainties expressed as discrete intervals and probability distributions. • Demand response program was introduced to adjust the deviation in real-time market. • Financial penalty for imbalance risk from wind power generation was evaluated.

  16. Mean-variance model for portfolio optimization with background risk based on uncertainty theory

    Science.gov (United States)

    Zhai, Jia; Bai, Manying

    2018-04-01

    The aim of this paper is to develop a mean-variance model for portfolio optimization considering the background risk, liquidity and transaction cost based on uncertainty theory. In portfolio selection problem, returns of securities and assets liquidity are assumed as uncertain variables because of incidents or lacking of historical data, which are common in economic and social environment. We provide crisp forms of the model and a hybrid intelligent algorithm to solve it. Under a mean-variance framework, we analyze the portfolio frontier characteristic considering independently additive background risk. In addition, we discuss some effects of background risk and liquidity constraint on the portfolio selection. Finally, we demonstrate the proposed models by numerical simulations.

  17. Cyanobacterial toxins: risk management for health protection

    International Nuclear Information System (INIS)

    Codd, Geoffrey A.; Morrison, Louise F.; Metcalf, James S.

    2005-01-01

    This paper reviews the occurrence and properties of cyanobacterial toxins, with reference to the recognition and management of the human health risks which they may present. Mass populations of toxin-producing cyanobacteria in natural and controlled waterbodies include blooms and scums of planktonic species, and mats and biofilms of benthic species. Toxic cyanobacterial populations have been reported in freshwaters in over 45 countries, and in numerous brackish, coastal, and marine environments. The principal toxigenic genera are listed. Known sources of the families of cyanobacterial toxins (hepato-, neuro-, and cytotoxins, irritants, and gastrointestinal toxins) are briefly discussed. Key procedures in the risk management of cyanobacterial toxins and cells are reviewed, including derivations (where sufficient data are available) of tolerable daily intakes (TDIs) and guideline values (GVs) with reference to the toxins in drinking water, and guideline levels for toxigenic cyanobacteria in bathing waters. Uncertainties and some gaps in knowledge are also discussed, including the importance of exposure media (animal and plant foods), in addition to potable and recreational waters. Finally, we present an outline of steps to develop and implement risk management strategies for cyanobacterial cells and toxins in waterbodies, with recent applications and the integration of Hazard Assessment Critical Control Point (HACCP) principles

  18. Economic policy uncertainty, credit risks and banks lending decisions: Evidence from Chinese commercial banks

    Institute of Scientific and Technical Information of China (English)

    Qinwei Chi; Wenjing Li

    2017-01-01

    Using data for Chinese commercial banks from 2000 to 2014, this paper examines the effects of economic policy uncertainty(EPU) on banks’ credit risks and lending decisions. The results reveal significantly positive connections among EPU and non-performing loan ratios, loan concentrations and the normal loan migration rate. This indicates that EPU increases banks’ credit risks and negatively influences loan size, especially for joint-equity banks. Given the increasing credit risks generated by EPU, banks can improve operational performance by reducing loan sizes. Further research indicates that the effects of EPU on banks’ credit risks and lending decisions are moderated by the marketization level, with financial depth moderating the effect on banks’ credit risks and strengthening it on lending decisions.

  19. Health and environmental risk governance in the french context. The role of scientific expertise and economic analysis

    International Nuclear Information System (INIS)

    Courvalin, C.; Boisson, P.; Dab, W.; Cohen de Lara, M.; Godard, O.; Heriard Dubreuil, G.; Hervouet, V.

    1998-01-01

    Full text of publication follows: increasing public concern as regards health and environmental risks makes it necessary, for public policies and regulation of risk assessment and management to comply with multiple and often non consistent expectations from the public in a rapidly changing environment. Evolution of risk assessment and management is currently observed as a consequence of this context. Whereas the former technical approaches were playing down the existence of residual risk as well as scientific uncertainties, current reflections rather aim at empowering the stakeholders of hazardous activities in the decision-making process in order to build up social trust and public confidence. This paper will present the conclusions of a work group entrusted by the French authorities with the task of proposing recommendations in order to update the risk assessment and management current approaches in the field of energy producing and consuming. The conclusions of this work are based on the analysis of three major issues as regards environmental health risks: climate change, atmospheric pollution, and radiation protection. It is also based on the 1997 report of the US Congress Commission on risk assessment and management. The report points out the difficulty for the French 'command and control' regulatory tradition to comply with public demand for transparency and more democratic involvement in the decision-making process. The conclusion presents various recommendations as regards the role of scientific expertise, the use of economic analysis and the decision-making process in risk assessment and management. The conclusion particularly emphasises key aspects of the decision-making process such as: the necessity of contextualizing risk assessment, the taking into account of scientific uncertainties and the need for stakeholders' involvement. (authors)

  20. Health risks in perspective: Judging health risks of energy technologies

    Energy Technology Data Exchange (ETDEWEB)

    Rowe, M.D.

    1992-09-18

    Almost daily, Americans receive reports from the mass news media about some new and frightening risk to health and welfare. Most such reports emphasize the newsworthiness of the risks -- the possibility of a crisis, disagreements among experts, how things happened, who is responsible for fixing them, how much will it cost, conflict among parties involved, etc. As a rule, the magnitudes of the risks, or the difficulty of estimating those magnitudes, have limited newsworthiness, and so they are not mentioned. Because of this emphasis in the news media, most people outside the risk assessment community must judge the relative significance of the various risks to which we all are exposed with only that information deemed newsworthy by reporters. This information is biased and shows risks in isolation. There is no basis for understanding and comparing the relative importance of risks among themselves, or for comparing one risk, perhaps a new or newly-discovered one, in the field of all risks. The purpose of this report is to provide perspective on the various risks to which we are routinely exposed. It serves as a basis for understanding the meaning of quantitative risk estimates and for comparing new or newly-discovered risks with other, better-understood risks. Specific emphasis is placed on health risks of energy technologies.

  1. Health and environmental risk-related impacts of actinide burning on high-level waste disposal

    International Nuclear Information System (INIS)

    Forsberg, C.W.

    1992-05-01

    The potential health and environmental risk-related impacts of actinide burning for high-level waste disposal were evaluated. Actinide burning, also called waste partitioning-transmutation, is an advanced method for radioactive waste management based on the idea of destroying the most toxic components in the waste. It consists of two steps: (1) selective removal of the most toxic radionuclides from high-level/spent fuel waste and (2) conversion of those radionuclides into less toxic radioactive materials and/or stable elements. Risk, as used in this report, is defined as the probability of a failure times its consequence. Actinide burning has two potential health and environmental impacts on waste management. Risks and the magnitude of high-consequence repository failure scenarios are decreased by inventory reduction of the long-term radioactivity in the repository. (What does not exist cannot create risk or uncertainty.) Risk may also be reduced by the changes in the waste characteristics, resulting from selection of waste forms after processing, that are superior to spent fuel and which lower the potential of transport of radionuclides from waste form to accessible environment. There are no negative health or environmental impacts to the repository from actinide burning; however, there may be such impacts elsewhere in the fuel cycle

  2. Identifying Selected Behavioral Determinants of Risk and Uncertainty on the Real Estate Market

    Directory of Open Access Journals (Sweden)

    Brzezicka Justyna

    2014-07-01

    Full Text Available Various market behaviors can be characterized as risky or uncertain, thus their observation is important to the real estate market system. The extensive use of behavioral factors facilitates their implementation and studies in relation to the real estate market system. The behavioral approach has established its own instrumentation which enables elements of risk and uncertainty to be quantified.

  3. Application of a Novel Dose-Uncertainty Model for Dose-Uncertainty Analysis in Prostate Intensity-Modulated Radiotherapy

    International Nuclear Information System (INIS)

    Jin Hosang; Palta, Jatinder R.; Kim, You-Hyun; Kim, Siyong

    2010-01-01

    Purpose: To analyze dose uncertainty using a previously published dose-uncertainty model, and to assess potential dosimetric risks existing in prostate intensity-modulated radiotherapy (IMRT). Methods and Materials: The dose-uncertainty model provides a three-dimensional (3D) dose-uncertainty distribution in a given confidence level. For 8 retrospectively selected patients, dose-uncertainty maps were constructed using the dose-uncertainty model at the 95% CL. In addition to uncertainties inherent to the radiation treatment planning system, four scenarios of spatial errors were considered: machine only (S1), S1 + intrafraction, S1 + interfraction, and S1 + both intrafraction and interfraction errors. To evaluate the potential risks of the IMRT plans, three dose-uncertainty-based plan evaluation tools were introduced: confidence-weighted dose-volume histogram, confidence-weighted dose distribution, and dose-uncertainty-volume histogram. Results: Dose uncertainty caused by interfraction setup error was more significant than that of intrafraction motion error. The maximum dose uncertainty (95% confidence) of the clinical target volume (CTV) was smaller than 5% of the prescribed dose in all but two cases (13.9% and 10.2%). The dose uncertainty for 95% of the CTV volume ranged from 1.3% to 2.9% of the prescribed dose. Conclusions: The dose uncertainty in prostate IMRT could be evaluated using the dose-uncertainty model. Prostate IMRT plans satisfying the same plan objectives could generate a significantly different dose uncertainty because a complex interplay of many uncertainty sources. The uncertainty-based plan evaluation contributes to generating reliable and error-resistant treatment plans.

  4. Methods for handling uncertainty within pharmaceutical funding decisions

    Science.gov (United States)

    Stevenson, Matt; Tappenden, Paul; Squires, Hazel

    2014-01-01

    This article provides a position statement regarding decision making under uncertainty within the economic evaluation of pharmaceuticals, with a particular focus upon the National Institute for Health and Clinical Excellence context within England and Wales. This area is of importance as funding agencies have a finite budget from which to purchase a selection of competing health care interventions. The objective function generally used is that of maximising societal health with an explicit acknowledgement that there will be opportunity costs associated with purchasing a particular intervention. Three components of uncertainty are discussed within a pharmaceutical funding perspective: methodological uncertainty, parameter uncertainty and structural uncertainty, alongside a discussion of challenges that are particularly pertinent to health economic evaluation. The discipline has focused primarily on handling methodological and parameter uncertainty and a clear reference case has been developed for consistency across evaluations. However, uncertainties still remain. Less attention has been given to methods for handling structural uncertainty. The lack of adequate methods to explicitly incorporate this aspect of model development may result in the true uncertainty surrounding health care investment decisions being underestimated. Research in this area is ongoing as we review.

  5. Risk management in architectural design control of uncertainty over building use and maintenance

    CERN Document Server

    Martani, Claudio

    2015-01-01

    This book analyzes the risk management process in relation to building design and operation and on this basis proposes a method and a set of tools that will improve the planning and evaluation of design solutions in order to control risks in the operation and management phase. Particular attention is paid to the relationship between design choices and the long-term performance of buildings in meeting requirements expressing user and client needs. A risk dashboard is presented as a risk measurement framework that identifies and addresses areas of uncertainty surrounding the satisfaction of particularly relevant requirements over time. This risk dashboard will assist both designers and clients. It will support designers by enabling them to improve the maintainability of project performance and will aid clients both in devising a brief that emphasizes the most relevant aspects of maintainability and in evaluating project proposals according to long-term risks. The results of assessment of the proposed method and...

  6. Effect Of Ventilation On Chronic Health Risks In Schools And Offices

    Energy Technology Data Exchange (ETDEWEB)

    Parthasarathy, Srinandini [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Fisk, William J. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); McKone, Thomas E. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2013-01-04

    This study provides a risk assessment for chronic health risks from inhalation exposure to indoor air pollutants in offices and schools with a focus how ventilation impacts exposures to, and risks from, volatile organic compounds (VOCs) and particulate matter (PM2.5). We estimate how much health risks could change with varying ventilation rates under two scenarios: (i) halving the measured ventilation rates and (ii) doubling the measured ventilation rates. For the hazard characterization we draw upon prior papers that identified pollutants potentially affecting health with indoor air concentrations responsive to changes in ventilation rates. For exposure assessment we determine representative concentrations of pollutants using data available in current literature and model changes in exposures with changes in ventilation rates. As a metric of disease burden, we use disability adjusted life years (DALYs) to address both cancer and non-cancer effects. We also compare exposures to guidelines published by regulatory agencies to assess chronic health risks. Chronic health risks are driven primarily by particulate matter exposure, with an estimated baseline disease burden of 150 DALYs per 100,000 people in offices and 140 DALYs per 100,000 people in schools. Study results show that PM2.5-related DALYs are not very sensitive to changes in ventilation rates. Filtration is more effective at controlling PM2.5 concentrations and health effects. Non-cancer health effects contribute only a small fraction of the overall chronic health burden of populations in offices and schools (<1 DALY per 100,000 people). Cancer health effects dominate the disease burden in schools (3 DALYs per 100,000) and offices (5 DALYs per 100,000), with formaldehyde being the primary risk driver. In spite of large uncertainties in toxicological data and dose-response modeling, our results support the finding that ventilation rate changes do not have significant impacts on estimated chronic disease

  7. Safety Goal, Multi-unit Risk and PSA Uncertainty

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Joon-Eon [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-10-15

    The safety goal is an answer of each country to the question 'How safe is safe enough?'. Table 1 shows some examples of the safety goal. However, many countries including Korea do not have the official safety goal for NPPs up to now since the establishment of safety goal is not just a technical issue but a very complex socio-technical issue. In establishing the safety goal for nuclear facilities, we have to consider various factors including not only technical aspects but also social, cultural ones. Recently, Korea is trying to establish the official safety goal. In this paper, we will review the relationship between the safety goal and Probabilistic Safety Assessment (PSA). We will also address some important technical issues to be considered in establishing the safety goal for NPPs from PSA point of view, i.e. a multi-unit risk issue and the uncertainty of PSA. In this paper, we reviewed some issues related to the safety goal and PSA. We believe that the safety goal is to be established in Korea considering the multi-unit risk. In addition, the relationship between the safety goal and PSA should be also defined clearly since PSA is the only way to answer to the question 'How safe is safe enough?'.

  8. Assessing Your Weight and Health Risk

    Science.gov (United States)

    ... Health Professional Resources Assessing Your Weight and Health Risk Assessment of weight and health risk involves using ... risk for developing obesity-associated diseases or conditions. Risk Factors for Health Topics Associated With Obesity Along ...

  9. Uncertainty analysis guide

    International Nuclear Information System (INIS)

    Andres, T.H.

    2002-05-01

    This guide applies to the estimation of uncertainty in quantities calculated by scientific, analysis and design computer programs that fall within the scope of AECL's software quality assurance (SQA) manual. The guide weaves together rational approaches from the SQA manual and three other diverse sources: (a) the CSAU (Code Scaling, Applicability, and Uncertainty) evaluation methodology; (b) the ISO Guide,for the Expression of Uncertainty in Measurement; and (c) the SVA (Systems Variability Analysis) method of risk analysis. This report describes the manner by which random and systematic uncertainties in calculated quantities can be estimated and expressed. Random uncertainty in model output can be attributed to uncertainties of inputs. The propagation of these uncertainties through a computer model can be represented in a variety of ways, including exact calculations, series approximations and Monte Carlo methods. Systematic uncertainties emerge from the development of the computer model itself, through simplifications and conservatisms, for example. These must be estimated and combined with random uncertainties to determine the combined uncertainty in a model output. This report also addresses the method by which uncertainties should be employed in code validation, in order to determine whether experiments and simulations agree, and whether or not a code satisfies the required tolerance for its application. (author)

  10. Uncertainty analysis guide

    Energy Technology Data Exchange (ETDEWEB)

    Andres, T.H

    2002-05-01

    This guide applies to the estimation of uncertainty in quantities calculated by scientific, analysis and design computer programs that fall within the scope of AECL's software quality assurance (SQA) manual. The guide weaves together rational approaches from the SQA manual and three other diverse sources: (a) the CSAU (Code Scaling, Applicability, and Uncertainty) evaluation methodology; (b) the ISO Guide,for the Expression of Uncertainty in Measurement; and (c) the SVA (Systems Variability Analysis) method of risk analysis. This report describes the manner by which random and systematic uncertainties in calculated quantities can be estimated and expressed. Random uncertainty in model output can be attributed to uncertainties of inputs. The propagation of these uncertainties through a computer model can be represented in a variety of ways, including exact calculations, series approximations and Monte Carlo methods. Systematic uncertainties emerge from the development of the computer model itself, through simplifications and conservatisms, for example. These must be estimated and combined with random uncertainties to determine the combined uncertainty in a model output. This report also addresses the method by which uncertainties should be employed in code validation, in order to determine whether experiments and simulations agree, and whether or not a code satisfies the required tolerance for its application. (author)

  11. Relevance and reliability of experimental data in human health risk assessment of pesticides.

    Science.gov (United States)

    Kaltenhäuser, Johanna; Kneuer, Carsten; Marx-Stoelting, Philip; Niemann, Lars; Schubert, Jens; Stein, Bernd; Solecki, Roland

    2017-08-01

    Evaluation of data relevance, reliability and contribution to uncertainty is crucial in regulatory health risk assessment if robust conclusions are to be drawn. Whether a specific study is used as key study, as additional information or not accepted depends in part on the criteria according to which its relevance and reliability are judged. In addition to GLP-compliant regulatory studies following OECD Test Guidelines, data from peer-reviewed scientific literature have to be evaluated in regulatory risk assessment of pesticide active substances. Publications should be taken into account if they are of acceptable relevance and reliability. Their contribution to the overall weight of evidence is influenced by factors including test organism, study design and statistical methods, as well as test item identification, documentation and reporting of results. Various reports make recommendations for improving the quality of risk assessments and different criteria catalogues have been published to support evaluation of data relevance and reliability. Their intention was to guide transparent decision making on the integration of the respective information into the regulatory process. This article describes an approach to assess the relevance and reliability of experimental data from guideline-compliant studies as well as from non-guideline studies published in the scientific literature in the specific context of uncertainty and risk assessment of pesticides. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  12. Assessing the joint impact of DNAPL source-zone behavior and degradation products on the probabilistic characterization of human health risk

    Science.gov (United States)

    Henri, Christopher V.; Fernàndez-Garcia, Daniel; de Barros, Felipe P. J.

    2016-02-01

    The release of industrial contaminants into the subsurface has led to a rapid degradation of groundwater resources. Contamination caused by Dense Non-Aqueous Phase Liquids (DNAPLs) is particularly severe owing to their limited solubility, slow dissolution and in many cases high toxicity. A greater insight into how the DNAPL source zone behavior and the contaminant release towards the aquifer impact human health risk is crucial for an appropriate risk management. Risk analysis is further complicated by the uncertainty in aquifer properties and contaminant conditions. This study focuses on the impact of the DNAPL release mode on the human health risk propagation along the aquifer under uncertain conditions. Contaminant concentrations released from the source zone are described using a screening approach with a set of parameters representing several scenarios of DNAPL architecture. The uncertainty in the hydraulic properties is systematically accounted for by high-resolution Monte Carlo simulations. We simulate the release and the transport of the chlorinated solvent perchloroethylene and its carcinogenic degradation products in randomly heterogeneous porous media. The human health risk posed by the chemical mixture of these contaminants is characterized by the low-order statistics and the probability density function of common risk metrics. We show that the zone of high risk (hot spot) is independent of the DNAPL mass release mode, and that the risk amplitude is mostly controlled by heterogeneities and by the source zone architecture. The risk is lower and less uncertain when the source zone is formed mostly by ganglia than by pools. We also illustrate how the source zone efficiency (intensity of the water flux crossing the source zone) affects the risk posed by an exposure to the chemical mixture. Results display that high source zone efficiencies are counter-intuitively beneficial, decreasing the risk because of a reduction in the time available for the production

  13. Uncertainty analysis for Ulysses safety evaluation report

    International Nuclear Information System (INIS)

    Frank, M.V.

    1991-01-01

    As part of the effort to review the Ulysses Final Safety Analysis Report and to understand the risk of plutonium release from the Ulysses spacecraft General Purpose Heat Source---Radioisotope Thermal Generator (GPHS-RTG), the Interagency Nuclear Safety Review Panel (INSRP) and the author performed an integrated, quantitative analysis of the uncertainties of the calculated risk of plutonium release from Ulysses. Using state-of-art probabilistic risk assessment technology, the uncertainty analysis accounted for both variability and uncertainty of the key parameters of the risk analysis. The results show that INSRP had high confidence that risk of fatal cancers from potential plutonium release associated with calculated launch and deployment accident scenarios is low

  14. Uncertainty theory

    CERN Document Server

    Liu, Baoding

    2015-01-01

    When no samples are available to estimate a probability distribution, we have to invite some domain experts to evaluate the belief degree that each event will happen. Perhaps some people think that the belief degree should be modeled by subjective probability or fuzzy set theory. However, it is usually inappropriate because both of them may lead to counterintuitive results in this case. In order to rationally deal with belief degrees, uncertainty theory was founded in 2007 and subsequently studied by many researchers. Nowadays, uncertainty theory has become a branch of axiomatic mathematics for modeling belief degrees. This is an introductory textbook on uncertainty theory, uncertain programming, uncertain statistics, uncertain risk analysis, uncertain reliability analysis, uncertain set, uncertain logic, uncertain inference, uncertain process, uncertain calculus, and uncertain differential equation. This textbook also shows applications of uncertainty theory to scheduling, logistics, networks, data mining, c...

  15. Handling Uncertainty in Social Lending Credit Risk Prediction with a Choquet Fuzzy Integral Model

    OpenAIRE

    Namvar, Anahita; Naderpour, Mohsen

    2018-01-01

    As one of the main business models in the financial technology field, peer-to-peer (P2P) lending has disrupted traditional financial services by providing an online platform for lending money that has remarkably reduced financial costs. However, the inherent uncertainty in P2P loans can result in huge financial losses for P2P platforms. Therefore, accurate risk prediction is critical to the success of P2P lending platforms. Indeed, even a small improvement in credit risk prediction would be o...

  16. Development of Property Models with Uncertainty Estimate for Process Design under Uncertainty

    DEFF Research Database (Denmark)

    Hukkerikar, Amol; Sarup, Bent; Abildskov, Jens

    more reliable predictions with a new and improved set of model parameters for GC (group contribution) based and CI (atom connectivity index) based models and to quantify the uncertainties in the estimated property values from a process design point-of-view. This includes: (i) parameter estimation using....... The comparison of model prediction uncertainties with reported range of measurement uncertainties is presented for the properties with related available data. The application of the developed methodology to quantify the effect of these uncertainties on the design of different unit operations (distillation column......, the developed methodology can be used to quantify the sensitivity of process design to uncertainties in property estimates; obtain rationally the risk/safety factors in process design; and identify additional experimentation needs in order to reduce most critical uncertainties....

  17. TREATING UNCERTAINTIES IN A NUCLEAR SEISMIC PROBABILISTIC RISK ASSESSMENT BY MEANS OF THE DEMPSTER-SHAFER THEORY OF EVIDENCE

    Directory of Open Access Journals (Sweden)

    CHUNG-KUNG LO

    2014-02-01

    Full Text Available The analyses carried out within the Seismic Probabilistic Risk Assessments (SPRAs of Nuclear Power Plants (NPPs are affected by significant aleatory and epistemic uncertainties. These uncertainties have to be represented and quantified coherently with the data, information and knowledge available, to provide reasonable assurance that related decisions can be taken robustly and with confidence. The amount of data, information and knowledge available for seismic risk assessment is typically limited, so that the analysis must strongly rely on expert judgments. In this paper, a Dempster-Shafer Theory (DST framework for handling uncertainties in NPP SPRAs is proposed and applied to an example case study. The main contributions of this paper are two: (i applying the complete DST framework to SPRA models, showing how to build the Dempster-Shafer structures of the uncertainty parameters based on industry generic data, and (ii embedding Bayesian updating based on plant specific data into the framework. The results of the application to a case study show that the approach is feasible and effective in (i describing and jointly propagating aleatory and epistemic uncertainties in SPRA models and (ii providing ‘conservative’ bounds on the safety quantities of interest (i.e. Core Damage Frequency, CDF that reflect the (limited state of knowledge of the experts about the system of interest.

  18. Key drivers and economic consequences of high-end climate scenarios: uncertainties and risks

    DEFF Research Database (Denmark)

    Halsnæs, Kirsten; Kaspersen, Per Skougaard; Drews, Martin

    2015-01-01

    The consequences of high-end climate scenarios and the risks of extreme events involve a number of critical assumptions and methodological challenges related to key uncertainties in climate scenarios and modelling, impact analysis, and economics. A methodological framework for integrated analysis...... of extreme events increase beyond scaling, and in combination with economic assumptions we find a very wide range of risk estimates for urban precipitation events. A sensitivity analysis addresses 32 combinations of climate scenarios, damage cost curve approaches, and economic assumptions, including risk...... aversion and equity represented by discount rates. Major impacts of alternative assumptions are investigated. As a result, this study demonstrates that in terms of decision making the actual expectations concerning future climate scenarios and the economic assumptions applied are very important...

  19. Accounting for Epistemic Uncertainty in Mission Supportability Assessment: A Necessary Step in Understanding Risk and Logistics Requirements

    Science.gov (United States)

    Owens, Andrew; De Weck, Olivier L.; Stromgren, Chel; Goodliff, Kandyce; Cirillo, William

    2017-01-01

    Future crewed missions to Mars present a maintenance logistics challenge that is unprecedented in human spaceflight. Mission endurance – defined as the time between resupply opportunities – will be significantly longer than previous missions, and therefore logistics planning horizons are longer and the impact of uncertainty is magnified. Maintenance logistics forecasting typically assumes that component failure rates are deterministically known and uses them to represent aleatory uncertainty, or uncertainty that is inherent to the process being examined. However, failure rates cannot be directly measured; rather, they are estimated based on similarity to other components or statistical analysis of observed failures. As a result, epistemic uncertainty – that is, uncertainty in knowledge of the process – exists in failure rate estimates that must be accounted for. Analyses that neglect epistemic uncertainty tend to significantly underestimate risk. Epistemic uncertainty can be reduced via operational experience; for example, the International Space Station (ISS) failure rate estimates are refined using a Bayesian update process. However, design changes may re-introduce epistemic uncertainty. Thus, there is a tradeoff between changing a design to reduce failure rates and operating a fixed design to reduce uncertainty. This paper examines the impact of epistemic uncertainty on maintenance logistics requirements for future Mars missions, using data from the ISS Environmental Control and Life Support System (ECLS) as a baseline for a case study. Sensitivity analyses are performed to investigate the impact of variations in failure rate estimates and epistemic uncertainty on spares mass. The results of these analyses and their implications for future system design and mission planning are discussed.

  20. Quantification of margins and uncertainties: Alternative representations of epistemic uncertainty

    International Nuclear Information System (INIS)

    Helton, Jon C.; Johnson, Jay D.

    2011-01-01

    In 2001, the National Nuclear Security Administration of the U.S. Department of Energy in conjunction with the national security laboratories (i.e., Los Alamos National Laboratory, Lawrence Livermore National Laboratory and Sandia National Laboratories) initiated development of a process designated Quantification of Margins and Uncertainties (QMU) for the use of risk assessment methodologies in the certification of the reliability and safety of the nation's nuclear weapons stockpile. A previous presentation, 'Quantification of Margins and Uncertainties: Conceptual and Computational Basis,' describes the basic ideas that underlie QMU and illustrates these ideas with two notional examples that employ probability for the representation of aleatory and epistemic uncertainty. The current presentation introduces and illustrates the use of interval analysis, possibility theory and evidence theory as alternatives to the use of probability theory for the representation of epistemic uncertainty in QMU-type analyses. The following topics are considered: the mathematical structure of alternative representations of uncertainty, alternative representations of epistemic uncertainty in QMU analyses involving only epistemic uncertainty, and alternative representations of epistemic uncertainty in QMU analyses involving a separation of aleatory and epistemic uncertainty. Analyses involving interval analysis, possibility theory and evidence theory are illustrated with the same two notional examples used in the presentation indicated above to illustrate the use of probability to represent aleatory and epistemic uncertainty in QMU analyses.

  1. Section summary: Uncertainty and design considerations

    Science.gov (United States)

    Stephen Hagen

    2013-01-01

    Well planned sampling designs and robust approaches to estimating uncertainty are critical components of forest monitoring. The importance of uncertainty estimation increases as deforestation and degradation issues become more closely tied to financing incentives for reducing greenhouse gas emissions in the forest sector. Investors like to know risk and risk is tightly...

  2. The risks of risk aversion in drug regulation.

    Science.gov (United States)

    Eichler, Hans-Georg; Bloechl-Daum, Brigitte; Brasseur, Daniel; Breckenridge, Alasdair; Leufkens, Hubert; Raine, June; Salmonson, Tomas; Schneider, Christian K; Rasi, Guido

    2013-12-01

    Drugs are approved by regulatory agencies on the basis of their assessment of whether the available evidence indicates that the benefits of the drug outweigh its risks. In recent years, regulatory agencies have been criticized both for being overly tolerant of risks or being excessively risk-averse, which reflects the challenge in determining an appropriate balance between benefit and risk with the limited data that is typically available before drug approval. The negative consequences of regulatory tolerance in allowing drugs onto the market that turn out to be unsafe are obvious, but the potential for adverse effects on public health owing to the absence of new drugs because of regulatory risk-aversion is less apparent. Here, we discuss the consequences of regulatory risk-aversion for public health and suggest what might be done to best align acceptance of risk and uncertainty by regulators with the interests of public health.

  3. Is imposing risk awareness cultural imperialism?

    Science.gov (United States)

    Førde, O H

    1998-11-01

    Epidemiology is the main supplier of "bases of action" for preventive medicine and health promotion. Epidemiology and epidemiologists therefore have a responsibility not only for the quality and soundness of the risk estimates they deliver and for the way they are interpreted and used, but also for their consequences. In the industrialised world, the value of, and fascination with health is greater than ever, and the revelation from epidemiological research of new hazards and risks, conveyed to the public by the media, has become almost an every-day phenomenon. This "risk epidemic" in the modern media is paralleled in professional medical journals. It is in general endorsed by health promoters as a necessary foundation for increased health awareness and a desirable impetus for people to take responsibility for their own health through behavioural changes. Epidemiologists and health promoters, however, have in general not taken the possible side effects of increased risk awareness seriously enough. By increasing anxiety regarding disease, accidents and other adverse events, the risk epidemic enhances both health care dependence and health care consumption. More profoundly, and perhaps even more seriously, it changes the way people think about health, disease and death--and ultimately and at least potentially, their perspective on life more generally. The message from the odds ratios from epidemiological research advocates a rationalistic, individualistic, prospective life perspective where maximising control and minimising uncertainty is seen as a superior goal. The inconsistency between applying an expanded health concept, comprising elements of coping, self-realisation and psycho-physical functioning, and imposing intolerance to risk and uncertainty, is regularly overlooked. Acceptance and tolerance of risk and uncertainty, which are inherent elements of human life, is a prerequisite for coping and self-realisation. A further shift away from traditional working

  4. 'In-between' and other reasonable ways to deal with risk and uncertainty: A review article.

    Science.gov (United States)

    Zinn, Jens O

    2016-11-16

    How people deal with risk and uncertainty has fuelled public and academic debate in recent decades. Researchers have shown that common distinctions between rational and 'irrational' strategies underestimate the complexity of how people approach an uncertain future. I suggested in 2008 that strategies in-between do not follow standards of instrumental rationality nor they are 'irrational' but follow their own logic which works well under particular circumstances. Strategies such as trust, intuition and emotion are an important part of the mix when people deal with risk and uncertainty. In this article, I develop my original argument. It explores in-between strategies to deal with possible undesired outcomes of decisions. I examine 'non-rational strategies' and in particular the notions of active, passive and reflexive hope. Furthermore, I argue that my original typology should be seen as a triangular of reasonable strategies which work well under specific circumstances. Finally, I highlight a number of different ways in which these strategies combine.

  5. County-Level Climate Uncertainty for Risk Assessments: Volume 25 Appendix X - Forecast Sea Ice Age.

    Energy Technology Data Exchange (ETDEWEB)

    Backus, George A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Lowry, Thomas Stephen [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Jones, Shannon M. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Walker, La Tonya Nicole [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Roberts, Barry L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Malczynski, Leonard A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-05-01

    This report uses the CMIP5 series of climate model simulations to produce country- level uncertainty distributions for use in socioeconomic risk assessments of climate change impacts. It provides appropriate probability distributions, by month, for 169 countries and autonomous-areas on temperature, precipitation, maximum temperature, maximum wind speed, humidity, runoff, soil moisture and evaporation for the historical period (1976-2005), and for decadal time periods to 2100. It also provides historical and future distributions for the Arctic region on ice concentration, ice thickness, age of ice, and ice ridging in 15-degree longitude arc segments from the Arctic Circle to 80 degrees latitude, plus two polar semicircular regions from 80 to 90 degrees latitude. The uncertainty is meant to describe the lack of knowledge rather than imprecision in the physical simulation because the emphasis is on unfalsified risk and its use to determine potential socioeconomic impacts. The full report is contained in 27 volumes.

  6. County-Level Climate Uncertainty for Risk Assessments: Volume 23 Appendix V - Forecast Sea Ice Thickness

    Energy Technology Data Exchange (ETDEWEB)

    Backus, George A.; Lowry, Thomas Stephen; Jones, Shannon M; Walker, La Tonya Nicole; Roberts, Barry L; Malczynski, Leonard A.

    2017-04-01

    This report uses the CMIP5 series of climate model simulations to produce country- level uncertainty distributions for use in socioeconomic risk assessments of climate change impacts. It provides appropriate probability distributions, by month, for 169 countries and autonomous-areas on temperature, precipitation, maximum temperature, maximum wind speed, humidity, runoff, soil moisture and evaporation for the historical period (1976-2005), and for decadal time periods to 2100. It also provides historical and future distributions for the Arctic region on ice concentration, ice thickness, age of ice, and ice ridging in 15-degree longitude arc segments from the Arctic Circle to 80 degrees latitude, plus two polar semicircular regions from 80 to 90 degrees latitude. The uncertainty is meant to describe the lack of knowledge rather than imprecision in the physical simulation because the emphasis is on unfalsified risk and its use to determine potential socioeconomic impacts. The full report is contained in 27 volumes.

  7. County-Level Climate Uncertainty for Risk Assessments: Volume 24 Appendix W - Historical Sea Ice Age.

    Energy Technology Data Exchange (ETDEWEB)

    Backus, George A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Lowry, Thomas Stephen [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Jones, Shannon M [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Walker, La Tonya Nicole [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Roberts, Barry L [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Malczynski, Leonard A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-05-01

    This report uses the CMIP5 series of climate model simulations to produce country- level uncertainty distributions for use in socioeconomic risk assessments of climate change impacts. It provides appropriate probability distributions, by month, for 169 countries and autonomous-areas on temperature, precipitation, maximum temperature, maximum wind speed, humidity, runoff, soil moisture and evaporation for the historical period (1976-2005), and for decadal time periods to 2100. It also provides historical and future distributions for the Arctic region on ice concentration, ice thickness, age of ice, and ice ridging in 15-degree longitude arc segments from the Arctic Circle to 80 degrees latitude, plus two polar semicircular regions from 80 to 90 degrees latitude. The uncertainty is meant to describe the lack of knowledge rather than imprecision in the physical simulation because the emphasis is on unfalsified risk and its use to determine potential socioeconomic impacts. The full report is contained in 27 volumes.

  8. County-Level Climate Uncertainty for Risk Assessments: Volume 22 Appendix U - Historical Sea Ice Thickness

    Energy Technology Data Exchange (ETDEWEB)

    Backus, George A.; Lowry, Thomas Stephen; Jones, Shannon M; Walker, La Tonya Nicole; Roberts, Barry L; Malczynski, Leonard A.

    2017-06-01

    This report uses the CMIP5 series of climate model simulations to produce country- level uncertainty distributions for use in socioeconomic risk assessments of climate change impacts. It provides appropriate probability distributions, by month, for 169 countries and autonomous-areas on temperature, precipitation, maximum temperature, maximum wind speed, humidity, runoff, soil moisture and evaporation for the historical period (1976-2005), and for decadal time periods to 2100. It also provides historical and future distributions for the Arctic region on ice concentration, ice thickness, age of ice, and ice ridging in 15-degree longitude arc segments from the Arctic Circle to 80 degrees latitude, plus two polar semicircular regions from 80 to 90 degrees latitude. The uncertainty is meant to describe the lack of knowledge rather than imprecision in the physical simulation because the emphasis is on unfalsified risk and its use to determine potential socioeconomic impacts. The full report is contained in 27 volumes.

  9. Two approaches to incorporate clinical data uncertainty into multiple criteria decision analysis for benefit-risk assessment of medicinal products.

    Science.gov (United States)

    Wen, Shihua; Zhang, Lanju; Yang, Bo

    2014-07-01

    The Problem formulation, Objectives, Alternatives, Consequences, Trade-offs, Uncertainties, Risk attitude, and Linked decisions (PrOACT-URL) framework and multiple criteria decision analysis (MCDA) have been recommended by the European Medicines Agency for structured benefit-risk assessment of medicinal products undergoing regulatory review. The objective of this article was to provide solutions to incorporate the uncertainty from clinical data into the MCDA model when evaluating the overall benefit-risk profiles among different treatment options. Two statistical approaches, the δ-method approach and the Monte-Carlo approach, were proposed to construct the confidence interval of the overall benefit-risk score from the MCDA model as well as other probabilistic measures for comparing the benefit-risk profiles between treatment options. Both approaches can incorporate the correlation structure between clinical parameters (criteria) in the MCDA model and are straightforward to implement. The two proposed approaches were applied to a case study to evaluate the benefit-risk profile of an add-on therapy for rheumatoid arthritis (drug X) relative to placebo. It demonstrated a straightforward way to quantify the impact of the uncertainty from clinical data to the benefit-risk assessment and enabled statistical inference on evaluating the overall benefit-risk profiles among different treatment options. The δ-method approach provides a closed form to quantify the variability of the overall benefit-risk score in the MCDA model, whereas the Monte-Carlo approach is more computationally intensive but can yield its true sampling distribution for statistical inference. The obtained confidence intervals and other probabilistic measures from the two approaches enhance the benefit-risk decision making of medicinal products. Copyright © 2014 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

  10. Evidence Theory Based Uncertainty Quantification in Radiological Risk due to Accidental Release of Radioactivity from a Nuclear Power Plant

    International Nuclear Information System (INIS)

    Ingale, S. V.; Datta, D.

    2010-01-01

    Consequence of the accidental release of radioactivity from a nuclear power plant is assessed in terms of exposure or dose to the members of the public. Assessment of risk is routed through this dose computation. Dose computation basically depends on the basic dose assessment model and exposure pathways. One of the exposure pathways is the ingestion of contaminated food. The aim of the present paper is to compute the uncertainty associated with the risk to the members of the public due to the ingestion of contaminated food. The governing parameters of the ingestion dose assessment model being imprecise, we have approached evidence theory to compute the bound of the risk. The uncertainty is addressed by the belief and plausibility fuzzy measures.

  11. Prediction of health risks from accidents: A comprehensive assessment methodology

    International Nuclear Information System (INIS)

    MacFarlane, D.R.; Yuan, Y.C.

    1992-01-01

    We have developed two computer programs to predict radiation risks to individuals and/or the collective population from exposures to accidental releases of radioactive materials. When used together, these two codes provide a consistent, comprehensive tool to estimate not only the risks to specific individuals but also the distribution of risks in the exposed population and the total number of individuals within a specific level of risk. Prompt and latent fatalities are estimated for the exposed population, and from these, the risk to an average individual can be derived. Uncertainty in weather conditions is considered by estimating both the ''median'' and the ''maximum'' population doses based on the frequency distribution of wind speeds and stabilities for a given site. The importance of including all dispersible particles (particles smaller than about 100 μm) for dose and health risk analyses from nonfiltered releases for receptor locations within about 10 km from a release has been investigated. The dose contribution of the large particles (> 10 μm) has been shown to be substantially greater than those from the small particles for the dose receptors in various release and exposure conditions. These conditions include, particularly, elevated releases, strong wind weather, and exposure pathways associated with ground-deposited material over extended periods of time

  12. Environmental modeling and health risk analysis (ACTS/RISK)

    National Research Council Canada - National Science Library

    Aral, M. M

    2010-01-01

    ... presents a review of the topics of exposure and health risk analysis. The Analytical Contaminant Transport Analysis System (ACTS) and Health RISK Analysis (RISK) software tools are an integral part of the book and provide computational platforms for all the models discussed herein. The most recent versions of these two softwa...

  13. Do Orthopaedic Surgeons Acknowledge Uncertainty?

    NARCIS (Netherlands)

    Teunis, Teun; Janssen, Stein; Guitton, Thierry G.; Ring, David; Parisien, Robert

    2016-01-01

    Much of the decision-making in orthopaedics rests on uncertain evidence. Uncertainty is therefore part of our normal daily practice, and yet physician uncertainty regarding treatment could diminish patients' health. It is not known if physician uncertainty is a function of the evidence alone or if

  14. Economic assessment of coal-fired and nuclear power generation in the year 2000 -Equal health hazard risk basis-

    International Nuclear Information System (INIS)

    Seong, Ki Bong; Lee, Byong Whi

    1989-01-01

    On the basis of equal health hazard risk, economic assessment of nuclear was compared with that of coal for the expansion planning of electric power generation in the year 2000. In comparing health risks, the risk of coal was roughly ten times higher than that of nuclear according to various previous risk assessments of energy system. The zero risk condition can never be achievable. Therefore, only excess relative health risk of coal over nuclear was considered as social cost. The social cost of health risk was estimated by calculation of mortality and morbidity costs. Mortality cost was $250,000 and morbidity cost was $90,000 in the year 2000.(1986US$) Through Cost/Benefit Analysis, the optimal emission standards of coal-fired power generation were predicted. These were obtained at the point of least social cost for power generation. In the year 2000, the optimal emission standard of SO x was analyzed as 165ppm for coal-fired power plants in Korea. From this assessment, economic comparison of nuclear and coal in the year 2000 showed that nuclear would be more economical than coal, whereas uncertainty of future power generation cost of nuclear would be larger than that of coal. (Author)

  15. Risk and Uncertainties, Analysis and Evaluation: Lessons for Adaptation and Integration

    International Nuclear Information System (INIS)

    Yohe, G.; Dowlatabadi, H.

    1999-01-01

    This paper draws ten lessons from analyses of adaptation to climate change under conditions of risk and uncertainty: (1) Socio-economic systems will likely respond most to extreme realizations of climate change. (2) Systems have been responding to variations in climate for centuries. (3) Future change will effect future citizens and their institutions. (4) Human systems can be the sources of surprise. (5) Perceptions of risk depend upon welfare valuations that depend upon expectations. (6) Adaptive decisions will be made in response to climate change and climate change policy. (7) Analysis of adaptive decisions should recognize the second-best context of those decisions. (8) Climate change offers opportunity as well as risk. (9) All plausible futures should be explored. (10) Multiple methodological approaches should be accommodated. These lessons support two pieces of advice for the Third Assessment Report: (1) Work toward consensus, but not at the expense of thorough examination and reporting of the 'tails' of the distributions of the future. (2) Integrated assessment is only one unifying methodology; others that can better accommodate those tails should be encouraged and embraced. 12 refs

  16. Irrigation, risk aversion, and water right priority under water supply uncertainty

    Science.gov (United States)

    Li, Man; Xu, Wenchao; Rosegrant, Mark W.

    2017-09-01

    This paper explores the impacts of a water right's allocative priority—as an indicator of farmers' risk-bearing ability—on land irrigation under water supply uncertainty. We develop and use an economic model to simulate farmers' land irrigation decision and associated economic returns in eastern Idaho. Results indicate that the optimal acreage of land irrigated increases with water right priority when hydroclimate risk exhibits a negatively skewed or right-truncated distribution. Simulation results suggest that prior appropriation enables senior water rights holders to allocate a higher proportion of their land to irrigation, 6 times as much as junior rights holders do, creating a gap in the annual expected net revenue reaching up to 141.4 acre-1 or 55,800 per farm between the two groups. The optimal irrigated acreage, expected net revenue, and shadow value of a water right's priority are subject to substantial changes under a changing climate in the future, where temporal variation in water supply risks significantly affects the profitability of agricultural land use under the priority-based water sharing mechanism.

  17. Contamination features and health risk of soil heavy metals in China

    International Nuclear Information System (INIS)

    Chen, Haiyang; Teng, Yanguo; Lu, Sijin; Wang, Yeyao; Wang, Jinsheng

    2015-01-01

    -Carlo simulation was used to analysis the uncertainty of health risk model

  18. Contamination features and health risk of soil heavy metals in China

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Haiyang [Engineering Research Center of Groundwater Pollution Control and Remediation, Ministry of Education, Beijing 100875 (China); College of Water Sciences, Beijing Normal University, Beijing 100875 (China); Teng, Yanguo, E-mail: Teng1974@163.com [Engineering Research Center of Groundwater Pollution Control and Remediation, Ministry of Education, Beijing 100875 (China); College of Water Sciences, Beijing Normal University, Beijing 100875 (China); Lu, Sijin; Wang, Yeyao [China National Environmental Monitoring Center, Beijing 100012 (China); Wang, Jinsheng [Engineering Research Center of Groundwater Pollution Control and Remediation, Ministry of Education, Beijing 100875 (China); College of Water Sciences, Beijing Normal University, Beijing 100875 (China)

    2015-04-15

    -Carlo simulation was used to analysis the uncertainty of health risk model.

  19. An interdisciplinary approach to volcanic risk reduction under conditions of uncertainty: a case study of Tristan da Cunha

    Science.gov (United States)

    Hicks, A.; Barclay, J.; Simmons, P.; Loughlin, S.

    2014-07-01

    The uncertainty brought about by intermittent volcanic activity is fairly common at volcanoes worldwide. While better knowledge of any one volcano's behavioural characteristics has the potential to reduce this uncertainty, the subsequent reduction of risk from volcanic threats is only realised if that knowledge is pertinent to stakeholders and effectively communicated to inform good decision making. Success requires integration of methods, skills and expertise across disciplinary boundaries. This research project develops and trials a novel interdisciplinary approach to volcanic risk reduction on the remote volcanic island of Tristan da Cunha (South Atlantic). For the first time, volcanological techniques, probabilistic decision support and social scientific methods were integrated in a single study. New data were produced that (1) established no spatio-temporal pattern to recent volcanic activity; (2) quantified the high degree of scientific uncertainty around future eruptive scenarios; (3) analysed the physical vulnerability of the community as a consequence of their geographical isolation and exposure to volcanic hazards; (4) evaluated social and cultural influences on vulnerability and resilience; and (5) evaluated the effectiveness of a scenario planning approach, both as a method for integrating the different strands of the research and as a way of enabling on-island decision makers to take ownership of risk identification and management, and capacity building within their community. The paper provides empirical evidence of the value of an innovative interdisciplinary framework for reducing volcanic risk. It also provides evidence for the strength that comes from integrating social and physical sciences with the development of effective, tailored engagement and communication strategies in volcanic risk reduction.

  20. Risk aversion, time preference and health production: theory and empirical evidence from Cambodia.

    Science.gov (United States)

    Rieger, Matthias

    2015-04-01

    This paper quantifies the relationship between risk aversion and discount rates on the one hand and height and weight on the other. It studies this link in the context of poor households in Cambodia. Evidence is based on an original dataset that contains both experimental measures of risk taking and impatience along with anthropometric measurements of children and adults. The aim of the paper is to (i) explore the importance of risk and time preferences in explaining undernutrition and (ii) compare the evidence stemming from poor households to strikingly similar findings from industrialized countries. It uses an inter-generational approach to explain observed correlations in adults and children that is inspired by the height premium on labor markets. Parents can invest in the health capital of their child to increase future earnings and their consumption when old: better nutrition during infancy translates into better human capital and better wages, and ultimately better financial means to take care of elderly parents. However this investment is subject to considerable uncertainty, since parents neither perfectly foresee economic conditions when the child starts earning nor fully observe the ability to transform nutritional investments into long-term health capital. As a result, risk taking households have taller and heavier children. Conversely, impatience does not affect child health. In the case of adults, only weight and the body mass index (BMI), but not height, are positively and moderately correlated with risk taking and impatience. Copyright © 2014 Elsevier B.V. All rights reserved.

  1. Decision making under uncertainty, therapeutic inertia, and physicians' risk preferences in the management of multiple sclerosis (DIScUTIR MS).

    Science.gov (United States)

    Saposnik, Gustavo; Sempere, Angel Perez; Raptis, Roula; Prefasi, Daniel; Selchen, Daniel; Maurino, Jorge

    2016-05-04

    The management of multiple sclerosis (MS) is rapidly changing by the introduction of new and more effective disease-modifying agents. The importance of risk stratification was confirmed by results on disease progression predicted by different risk score systems. Despite these advances, we know very little about medical decisions under uncertainty in the management of MS. The goal of this study is to i) identify whether overconfidence, tolerance to risk/uncertainty, herding influence medical decisions, and ii) to evaluate the frequency of therapeutic inertia (defined as lack of treatment initiation or intensification in patients not at goals of care) and its predisposing factors in the management of MS. This is a prospective study comprising a combination of case-vignettes and surveys and experiments from Neuroeconomics/behavioral economics to identify cognitive distortions associated with medical decisions and therapeutic inertia. Participants include MS fellows and MS experts from across Spain. Each participant will receive an individual link using Qualtrics platform(©) that includes 20 case-vignettes, 3 surveys, and 4 behavioral experiments. The total time for completing the study is approximately 30-35 min. Case vignettes were selected to be representative of common clinical encounters in MS practice. Surveys and experiments include standardized test to measure overconfidence, aversion to risk and ambiguity, herding (following colleague's suggestions even when not supported by the evidence), physicians' reactions to uncertainty, and questions from the Socio-Economic Panel Study (SOEP) related to risk preferences in different domains. By applying three different MS score criteria (modified Rio, EMA, Prosperini's scheme) we take into account physicians' differences in escalating therapy when evaluating medical decisions across case-vignettes. The present study applies an innovative approach by combining tools to assess medical decisions with experiments from

  2. Managing risks of market price uncertainty for a microgrid operation

    Science.gov (United States)

    Raghavan, Sriram

    After deregulation of electricity in the United States, the day-ahead and real-time markets allow load serving entities and generation companies to bid and purchase/sell energy under the supervision of the independent system operator (ISO). The electricity market prices are inherently uncertain, and can be highly volatile. The main objective of this thesis is to hedge against the risk from the uncertainty of the market prices when purchasing/selling energy from/to the market. The energy manager can also schedule distributed generators (DGs) and storage of the microgrid to meet the demand, in addition to energy transactions from the market. The risk measure used in this work is the variance of the uncertain market purchase/sale cost/revenue, assuming the price following a Gaussian distribution. Using Markowitz optimization, the risk is minimized to find the optimal mix of purchase from the markets. The problem is formulated as a mixed integer quadratic program. The microgrid at Illinois Institute of Technology (IIT) in Chicago, IL was used as a case study. The result of this work reveals the tradeoff faced by the microgrid energy manager between minimizing the risk and minimizing the mean of the total operating cost (TOC) of the microgrid. With this information, the microgrid energy manager can make decisions in the day-ahead and real-time markets according to their risk aversion preference. The assumption of market prices following Gaussian distribution is also verified to be reasonable for the purpose of hedging against their risks. This is done by comparing the result of the proposed formulation with that obtained from the sample market prices randomly generated using the distribution of actual historic market price data.

  3. Assessment of the health impact of an environmental pollution and quantitative assessment of health risks; Estimation de l'impact sanitaire d'une pollution environnementale et evaluation quantitative des risques sanitaires

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-09-15

    The report made by a working group is written for experts in health risk assessment or for professionals involved in risk management. It proposes a methodological and conceptual framework which could build a unified approach to a quantitative assessment of health risks. In the first part, under the form of questions and answers, it defines the health impact, describes how to assess the excess of individual risk and the related hypothesis, how to pass from the excess of individual risk to the health impact, how to express the results of an health impact calculation, how to take the lack of knowledge into account at the different steps of this calculation, what is the significance of the result of such a calculation, and how useful an health impact assessment can be. The second part proposes a more detailed presentation of the scientific background for the health impact calculation with its indicators, its uncertainties, its practice in other countries, its relevance, and its fields of application. Then, after a comment of the dose-response relationship, it reports the scientific validity of the assessment of a number of cases.

  4. Assessment of the Risk to Public Health due to Use of Antimicrobials in Pigs-An Example of Pleuromutilins in Denmark.

    Science.gov (United States)

    Alban, Lis; Ellis-Iversen, Johanne; Andreasen, Margit; Dahl, Jan; Sönksen, Ute W

    2017-01-01

    Antibiotic consumption in pigs can be optimized by developing treatment guidelines, which encourage veterinarians to use effective drugs with low probability of developing resistance of importance for human health. In Denmark, treatment guidelines for use in swine production are currently under review at the Danish Veterinary and Food Administration. Use of pleuromutilins in swine has previously been associated with a very low risk for human health. However, recent international data and sporadic findings of novel resistance genes suggest a change of risk. Consequently, a reassessment was undertaken inspired by a risk assessment framework developed by the European Medicines Agency. Livestock-associated methicillin-resistant Staphylococcus aureus of clonal complex 398 (MRSA CC398) and enterococci were identified as relevant hazards. The release assessment showed that the probability of development of pleuromutilin resistance was high in MRSA CC398 (medium uncertainty) and low in enterococci (high uncertainty). A relatively small proportion of Danes has an occupational exposure to pigs, and foodborne transmission was only considered of relevance for enterococci, resulting in an altogether low exposure risk. The human consequences of infection with pleuromutilin-resistant MRSA CC398 or enterococci were assessed as low for the public in general but high for vulnerable groups such as hospitalized and immunocompromised persons. For MRSA CC398, the total risk was estimated as low (low uncertainty), among other due to the current guidelines on prevention of MRSA in place at Danish hospitals, which include screening of patients with daily contact to pigs on admittance. Moreover, MRSA CC398 has a medium human-human transmission potential. For enterococci, the total risk was estimated as low due to low prevalence of resistance, low probability of spread to humans, low virulence, but no screening of hospitalized patients, high ability of acquiring resistance genes, and a

  5. Assessment of the Risk to Public Health due to Use of Antimicrobials in Pigs—An Example of Pleuromutilins in Denmark

    Directory of Open Access Journals (Sweden)

    Lis Alban

    2017-05-01

    Full Text Available Antibiotic consumption in pigs can be optimized by developing treatment guidelines, which encourage veterinarians to use effective drugs with low probability of developing resistance of importance for human health. In Denmark, treatment guidelines for use in swine production are currently under review at the Danish Veterinary and Food Administration. Use of pleuromutilins in swine has previously been associated with a very low risk for human health. However, recent international data and sporadic findings of novel resistance genes suggest a change of risk. Consequently, a reassessment was undertaken inspired by a risk assessment framework developed by the European Medicines Agency. Livestock-associated methicillin-resistant Staphylococcus aureus of clonal complex 398 (MRSA CC398 and enterococci were identified as relevant hazards. The release assessment showed that the probability of development of pleuromutilin resistance was high in MRSA CC398 (medium uncertainty and low in enterococci (high uncertainty. A relatively small proportion of Danes has an occupational exposure to pigs, and foodborne transmission was only considered of relevance for enterococci, resulting in an altogether low exposure risk. The human consequences of infection with pleuromutilin-resistant MRSA CC398 or enterococci were assessed as low for the public in general but high for vulnerable groups such as hospitalized and immunocompromised persons. For MRSA CC398, the total risk was estimated as low (low uncertainty, among other due to the current guidelines on prevention of MRSA in place at Danish hospitals, which include screening of patients with daily contact to pigs on admittance. Moreover, MRSA CC398 has a medium human–human transmission potential. For enterococci, the total risk was estimated as low due to low prevalence of resistance, low probability of spread to humans, low virulence, but no screening of hospitalized patients, high ability of acquiring resistance

  6. Risk Formulations versus Comprehensive Uncertainty Characterizations for Climate Extremes and their Impacts

    Science.gov (United States)

    Parish, E. S.; Ganguly, A. R.

    2009-12-01

    Climate extremes—defined inclusively as extreme hydro-metrological events and regional changes in climate patterns at decadal scales—and their impacts on natural, engineered or human systems, represent among the most significant knowledge-gaps in climate prediction and integrated assessments in a post-AR4 world. Risks and uncertainties are related but distinct concepts. However, their relevance to decision-support tools in the context of climate change is indisputable. The opportunities and challenges are presented with case studies developed for stakeholders and policy makers.

  7. Probabilistic risk assessment for CO2 storage in geological formations: robust design and support for decision making under uncertainty

    Science.gov (United States)

    Oladyshkin, Sergey; Class, Holger; Helmig, Rainer; Nowak, Wolfgang

    2010-05-01

    CO2 storage in geological formations is currently being discussed intensively as a technology for mitigating CO2 emissions. However, any large-scale application requires a thorough analysis of the potential risks. Current numerical simulation models are too expensive for probabilistic risk analysis and for stochastic approaches based on brute-force repeated simulation. Even single deterministic simulations may require parallel high-performance computing. The multiphase flow processes involved are too non-linear for quasi-linear error propagation and other simplified stochastic tools. As an alternative approach, we propose a massive stochastic model reduction based on the probabilistic collocation method. The model response is projected onto a orthogonal basis of higher-order polynomials to approximate dependence on uncertain parameters (porosity, permeability etc.) and design parameters (injection rate, depth etc.). This allows for a non-linear propagation of model uncertainty affecting the predicted risk, ensures fast computation and provides a powerful tool for combining design variables and uncertain variables into one approach based on an integrative response surface. Thus, the design task of finding optimal injection regimes explicitly includes uncertainty, which leads to robust designs of the non-linear system that minimize failure probability and provide valuable support for risk-informed management decisions. We validate our proposed stochastic approach by Monte Carlo simulation using a common 3D benchmark problem (Class et al. Computational Geosciences 13, 2009). A reasonable compromise between computational efforts and precision was reached already with second-order polynomials. In our case study, the proposed approach yields a significant computational speedup by a factor of 100 compared to Monte Carlo simulation. We demonstrate that, due to the non-linearity of the flow and transport processes during CO2 injection, including uncertainty in the analysis

  8. Knowledge management system for risk mitigation in supply chain uncertainty: case from automotive battery supply chain

    Science.gov (United States)

    Marie, I. A.; Sugiarto, D.; Surjasa, D.; Witonohadi, A.

    2018-01-01

    Automotive battery supply chain include battery manufacturer, sulphuric acid suppliers, polypropylene suppliers, lead suppliers, transportation service providers, warehouses, retailers and even customers. Due to the increasingly dynamic condition of the environment, supply chain actors were required to improve their ability to overcome various uncertainty issues in the environment. This paper aims to describe the process of designing a knowledge management system for risk mitigation in supply chain uncertainty. The design methodology began with the identification of the knowledge needed to solve the problems associated with uncertainty and analysis of system requirements. The design of the knowledge management system was described in the form of a data flow diagram. The results of the study indicated that key knowledge area that needs to be managed were the knowledge to maintain the stability of process in sulphuric acid process and knowledge to overcome the wastes in battery manufacturing process. The system was expected to be a media acquisition, dissemination and storage of knowledge associated with the uncertainty in the battery supply chain and increase the supply chain performance.

  9. Quantifying uncertainty in pest risk maps and assessments: adopting a risk-averse decision maker’s perspective

    Directory of Open Access Journals (Sweden)

    Denys Yemshanov

    2013-09-01

    Full Text Available Pest risk maps are important decision support tools when devising strategies to minimize introductions of invasive organisms and mitigate their impacts. When possible management responses to an invader include costly or socially sensitive activities, decision-makers tend to follow a more certain (i.e., risk-averse course of action. We presented a new mapping technique that assesses pest invasion risk from the perspective of a risk-averse decision maker.We demonstrated the method by evaluating the likelihood that an invasive forest pest will be transported to one of the U.S. states or Canadian provinces in infested firewood by visitors to U.S. federal campgrounds. We tested the impact of the risk aversion assumption using distributions of plausible pest arrival scenarios generated with a geographically explicit model developed from data documenting camper travel across the study area. Next, we prioritized regions of high and low pest arrival risk via application of two stochastic ordering techniques that employed, respectively, first- and second-degree stochastic dominance rules, the latter of which incorporated the notion of risk aversion. We then identified regions in the study area where the pest risk value changed considerably after incorporating risk aversion.While both methods identified similar areas of highest and lowest risk, they differed in how they demarcated moderate-risk areas. In general, the second-order stochastic dominance method assigned lower risk rankings to moderate-risk areas. Overall, this new method offers a better strategy to deal with the uncertainty typically associated with risk assessments and provides a tractable way to incorporate decision-making preferences into final risk estimates, and thus helps to better align these estimates with particular decision-making scenarios about a pest organism of concern. Incorporation of risk aversion also helps prioritize the set of locations to target for inspections and

  10. A Minimax Regret Analysis of Flood Risk Management Strategies Under Climate Change Uncertainty and Emerging Information

    NARCIS (Netherlands)

    Pol, van der T.D.; Gabbert, S.; Weikard, H.P.; Ierland, van E.C.; Hendrix, E.M.T.

    2017-01-01

    This paper studies the dynamic application of the minimax regret (MR) decision criterion to identify robust flood risk management strategies under climate change uncertainty and emerging information. An MR method is developed that uses multiple learning scenarios, for example about sea level rise

  11. Measurement, simulation and uncertainty assessment of implant heating during MRI

    International Nuclear Information System (INIS)

    Neufeld, E; Kuehn, S; Kuster, N; Szekely, G

    2009-01-01

    The heating of tissues around implants during MRI can pose severe health risks, and careful evaluation is required for leads to be labeled as MR conditionally safe. A recent interlaboratory comparison study has shown that different groups can produce widely varying results (sometimes with more than a factor of 5 difference) when performing measurements according to current guidelines. To determine the related difficulties and to derive optimized procedures, two different generic lead structures have been investigated in this study by using state-of-the-art temperature and dosimetric probes, as well as simulations for which detailed uncertainty budgets have been determined. The agreement between simulations and measurements is well within the combined uncertainty. The study revealed that the uncertainty can be kept below 17% if appropriate instrumentation and procedures are applied. Optimized experimental assessment techniques can be derived from the findings presented herein.

  12. Measurement, simulation and uncertainty assessment of implant heating during MRI

    Energy Technology Data Exchange (ETDEWEB)

    Neufeld, E; Kuehn, S; Kuster, N [Foundation for Research on Information Technologies in Society (IT' IS), Zeughausstr. 43, 8004 Zurich (Switzerland); Szekely, G [Computer Vision Laboratory, Swiss Federal Institute of Technology (ETHZ), Sternwartstr 7, ETH Zentrum, 8092 Zurich (Switzerland)], E-mail: neufeld@itis.ethz.ch

    2009-07-07

    The heating of tissues around implants during MRI can pose severe health risks, and careful evaluation is required for leads to be labeled as MR conditionally safe. A recent interlaboratory comparison study has shown that different groups can produce widely varying results (sometimes with more than a factor of 5 difference) when performing measurements according to current guidelines. To determine the related difficulties and to derive optimized procedures, two different generic lead structures have been investigated in this study by using state-of-the-art temperature and dosimetric probes, as well as simulations for which detailed uncertainty budgets have been determined. The agreement between simulations and measurements is well within the combined uncertainty. The study revealed that the uncertainty can be kept below 17% if appropriate instrumentation and procedures are applied. Optimized experimental assessment techniques can be derived from the findings presented herein.

  13. Risk, Uncertainty, and Entrepreneurship

    DEFF Research Database (Denmark)

    Koudstaal, Martin; Sloof, Randolph; Van Praag, Mirjam

    2016-01-01

    21288). The results indicate that entrepreneurs perceive themselves as less risk averse than managers and employees, in line with common wisdom. However, when using experimental incentivized measures, the differences are subtler. Entrepreneurs are only found to be unique in their lower degree of loss...... aversion, and not in their risk or ambiguity aversion. This combination of results might be explained by our finding that perceived risk attitude is not only correlated to risk aversion but also to loss aversion. Overall, we therefore suggest using a broader definition of risk that captures this unique...... feature of entrepreneurs: their willingness to risk losses....

  14. Assessment of mercury health risks to adults from coal combustion

    Energy Technology Data Exchange (ETDEWEB)

    Lipfert, F.W.; Moskowitz, P.D.; Fthenakis, V.M.; DePhillips, M.P.; Viren, J.; Saroff, L.

    1994-05-01

    The U.S. Environmental Protection Agency (EPA) is preparing, for the U.S. Congress, a report evaluating the need to regulate mercury (Hg) emissions from electric utilities. This study, to be completed in 1995, will have important health and economic implications. In support of these efforts, the U.S. Department of Energy, Office of Fossil Energy, sponsored a risk assessment project at Brookhaven National Laboratory (BNL) to evaluate methylmercury (MeHg) hazards independently. In the BNL study, health risks to adults resulting from Hg emissions from a hypothetical 1000 MW{sub e} coal-fired power plant were estimated using probabilistic risk assessment techniques. The approach draws on the extant knowledge in each of the important steps in the calculation chain from emissions to health effects. Estimated results at key points in the chain were compared with actual measurements to help validate the modeled estimates. Two cases were considered: the baseline case (no local impacts), and the impact case (maximum local power-plant impact). The BNL study showed that the effects of emissions of a single power plant may double the background exposures to MeHg resulting from consuming fish obtained from a localized area near the power plant. Many implicit and explicit sources of uncertainty exist in this analysis. Those that appear to be most in need of improvement include data on doses and responses for potentially sensitive subpopulations (e.g., fetal exposures). Rather than considering hypothetical situations, it would also be preferable to assess the risks associated with actual coal-fired power plants and the nearby sensitive water bodies and susceptible subpopulations. Finally, annual total Hg emissions from coal burning and from other anthropogenic sources are still uncertain; this makes it difficult to estimate the effects of U.S. coal burning on global Hg concentration levels, especially over the long term.

  15. Addendum to ‘Understanding risks in the light of uncertainty: low-probability, high-impact coastal events in cities’

    Science.gov (United States)

    Galarraga, Ibon; Sainz de Murieta, Elisa; Markandya, Anil; María Abadie, Luis

    2018-02-01

    This addendum adds to the analysis presented in ‘Understanding risks in the light of uncertainty: low-probability, high-impact coastal events in cities’ Abadie et al (2017 Environ. Res. Lett. 12 014017). We propose to use the framework developed earlier to enhance communication and understanding of risks, with the aim of bridging the gap between highly technical risk management discussion to the public risk aversion debate. We also propose that the framework could be used for stress-testing resilience.

  16. ‘In-between’ and other reasonable ways to deal with risk and uncertainty: A review article

    Science.gov (United States)

    Zinn, Jens O.

    2016-01-01

    How people deal with risk and uncertainty has fuelled public and academic debate in recent decades. Researchers have shown that common distinctions between rational and ‘irrational’ strategies underestimate the complexity of how people approach an uncertain future. I suggested in 2008 that strategies in-between do not follow standards of instrumental rationality nor they are ‘irrational’ but follow their own logic which works well under particular circumstances. Strategies such as trust, intuition and emotion are an important part of the mix when people deal with risk and uncertainty. In this article, I develop my original argument. It explores in-between strategies to deal with possible undesired outcomes of decisions. I examine ‘non-rational strategies’ and in particular the notions of active, passive and reflexive hope. Furthermore, I argue that my original typology should be seen as a triangular of reasonable strategies which work well under specific circumstances. Finally, I highlight a number of different ways in which these strategies combine. PMID:28392747

  17. County-Level Climate Uncertainty for Risk Assessments: Volume 2 Appendix A - Historical Near-Surface Air Temperature.

    Energy Technology Data Exchange (ETDEWEB)

    Backus, George A.; Lowry, Thomas Stephen; Jones, Shannon M; Walker, La Tonya Nicole; Roberts, Barry L; Malczynski, Leonard A.

    2017-06-01

    This report uses the CMIP5 series of climate model simulations to produce country- level uncertainty distributions for use in socioeconomic risk assessments of climate change impacts. It provides appropriate probability distributions, by month, for 169 countries and autonomous-areas on temperature, precipitation, maximum temperature, maximum wind speed, humidity, runoff, soil moisture and evaporation for the historical period (1976-2005), and for decadal time periods to 2100. It also provides historical and future distributions for the Arctic region on ice concentration, ice thickness, age of ice, and ice ridging in 15-degree longitude arc segments from the Arctic Circle to 80 degrees latitude, plus two polar semicircular regions from 80 to 90 degrees latitude. The uncertainty is meant to describe the lack of knowledge rather than imprecision in the physical simulation because the emphasis is on unfalsified risk and its use to determine potential socioeconomic impacts. The full report is contained in 27 volumes.

  18. County-Level Climate Uncertainty for Risk Assessments: Volume 21 Appendix T - Forecast Sea Ice Area Fraction.

    Energy Technology Data Exchange (ETDEWEB)

    Backus, George A.; Lowry, Thomas Stephen; Jones, Shannon M; Walker, La Tonya Nicole; Roberts, Barry L; Malczynski, Leonard A.

    2017-06-01

    This report uses the CMIP5 series of climate model simulations to produce country- level uncertainty distributions for use in socioeconomic risk assessments of climate change impacts. It provides appropriate probability distributions, by month, for 169 countries and autonomous-areas on temperature, precipitation, maximum temperature, maximum wind speed, humidity, runoff, soil moisture and evaporation for the historical period (1976-2005), and for decadal time periods to 2100. It also provides historical and future distributions for the Arctic region on ice concentration, ice thickness, age of ice, and ice ridging in 15-degree longitude arc segments from the Arctic Circle to 80 degrees latitude, plus two polar semicircular regions from 80 to 90 degrees latitude. The uncertainty is meant to describe the lack of knowledge rather than imprecision in the physical simulation because the emphasis is on unfalsified risk and its use to determine potential socioeconomic impacts. The full report is contained in 27 volumes.

  19. County-Level Climate Uncertainty for Risk Assessments: Volume 20 Appendix S - Historical Sea Ice Area Fraction

    Energy Technology Data Exchange (ETDEWEB)

    Backus, George A.; Lowry, Thomas Stephen; Jones, Shannon M; Walker, La Tonya Nicole; Roberts, Barry L; Malczynski, Leonard A.

    2017-06-01

    This report uses the CMIP5 series of climate model simulations to produce country- level uncertainty distributions for use in socioeconomic risk assessments of climate change impacts. It provides appropriate probability distributions, by month, for 169 countries and autonomous-areas on temperature, precipitation, maximum temperature, maximum wind speed, humidity, runoff, soil moisture and evaporation for the historical period (1976-2005), and for decadal time periods to 2100. It also provides historical and future distributions for the Arctic region on ice concentration, ice thickness, age of ice, and ice ridging in 15-degree longitude arc segments from the Arctic Circle to 80 degrees latitude, plus two polar semicircular regions from 80 to 90 degrees latitude. The uncertainty is meant to describe the lack of knowledge rather than imprecision in the physical simulation because the emphasis is on unfalsified risk and its use to determine potential socioeconomic impacts. The full report is contained in 27 volumes.

  20. Uncertainties and severe-accident management

    International Nuclear Information System (INIS)

    Kastenberg, W.E.

    1991-01-01

    Severe-accident management can be defined as the use of existing and or alternative resources, systems, and actions to prevent or mitigate a core-melt accident. Together with risk management (e.g., changes in plant operation and/or addition of equipment) and emergency planning (off-site actions), accident management provides an extension of the defense-indepth safety philosophy for severe accidents. A significant number of probabilistic safety assessments have been completed, which yield the principal plant vulnerabilities, and can be categorized as (a) dominant sequences with respect to core-melt frequency, (b) dominant sequences with respect to various risk measures, (c) dominant threats that challenge safety functions, and (d) dominant threats with respect to failure of safety systems. Severe-accident management strategies can be generically classified as (a) use of alternative resources, (b) use of alternative equipment, and (c) use of alternative actions. For each sequence/threat and each combination of strategy, there may be several options available to the operator. Each strategy/option involves phenomenological and operational considerations regarding uncertainty. These include (a) uncertainty in key phenomena, (b) uncertainty in operator behavior, (c) uncertainty in system availability and behavior, and (d) uncertainty in information availability (i.e., instrumentation). This paper focuses on phenomenological uncertainties associated with severe-accident management strategies

  1. Future bloom and blossom frost risk for Malus domestica considering climate model and impact model uncertainties.

    Science.gov (United States)

    Hoffmann, Holger; Rath, Thomas

    2013-01-01

    The future bloom and risk of blossom frosts for Malus domestica were projected using regional climate realizations and phenological ( = impact) models. As climate impact projections are susceptible to uncertainties of climate and impact models and model concatenation, the significant horizon of the climate impact signal was analyzed by applying 7 impact models, including two new developments, on 13 climate realizations of the IPCC emission scenario A1B. Advancement of phenophases and a decrease in blossom frost risk for Lower Saxony (Germany) for early and late ripeners was determined by six out of seven phenological models. Single model/single grid point time series of bloom showed significant trends by 2021-2050 compared to 1971-2000, whereas the joint signal of all climate and impact models did not stabilize until 2043. Regarding blossom frost risk, joint projection variability exceeded the projected signal. Thus, blossom frost risk cannot be stated to be lower by the end of the 21st century despite a negative trend. As a consequence it is however unlikely to increase. Uncertainty of temperature, blooming date and blossom frost risk projection reached a minimum at 2078-2087. The projected phenophases advanced by 5.5 d K(-1), showing partial compensation of delayed fulfillment of the winter chill requirement and faster completion of the following forcing phase in spring. Finally, phenological model performance was improved by considering the length of day.

  2. Exposure Estimation and Interpretation of Occupational Risk: Enhanced Information for the Occupational Risk Manager

    Science.gov (United States)

    Waters, Martha; McKernan, Lauralynn; Maier, Andrew; Jayjock, Michael; Schaeffer, Val; Brosseau, Lisa

    2015-01-01

    The fundamental goal of this article is to describe, define, and analyze the components of the risk characterization process for occupational exposures. Current methods are described for the probabilistic characterization of exposure, including newer techniques that have increasing applications for assessing data from occupational exposure scenarios. In addition, since the probability of health effects reflects variability in the exposure estimate as well as the dose-response curve—the integrated considerations of variability surrounding both components of the risk characterization provide greater information to the occupational hygienist. Probabilistic tools provide a more informed view of exposure as compared to use of discrete point estimates for these inputs to the risk characterization process. Active use of such tools for exposure and risk assessment will lead to a scientifically supported worker health protection program. Understanding the bases for an occupational risk assessment, focusing on important sources of variability and uncertainty enables characterizing occupational risk in terms of a probability, rather than a binary decision of acceptable risk or unacceptable risk. A critical review of existing methods highlights several conclusions: (1) exposure estimates and the dose-response are impacted by both variability and uncertainty and a well-developed risk characterization reflects and communicates this consideration; (2) occupational risk is probabilistic in nature and most accurately considered as a distribution, not a point estimate; and (3) occupational hygienists have a variety of tools available to incorporate concepts of risk characterization into occupational health and practice. PMID:26302336

  3. Risk, Uncertainty and Entrepreneurship

    DEFF Research Database (Denmark)

    Koudstaal, Martin; Sloof, Randolph; Van Praag, Mirjam

    . Entrepreneurs are only found to be unique in their lower degree of loss aversion, and not in their risk or ambiguity aversion. This combination of results might be explained by our finding that perceived risk attitude is not only correlated to risk aversion but also to loss aversion. Overall, we therefore...... entrepreneurs to managers – a suitable comparison group – and employees (n = 2288). The results indicate that entrepreneurs perceive themselves as less risk averse than managers and employees, in line with common wisdom. However, when using experimental incentivized measures, the differences are subtler...... suggest using a broader definition of risk that captures this unique feature of entrepreneurs; their willingness to risk losses....

  4. Health technology assessment and primary data collection for reducing uncertainty in decision making.

    Science.gov (United States)

    Goeree, Ron; Levin, Les; Chandra, Kiran; Bowen, James M; Blackhouse, Gord; Tarride, Jean-Eric; Burke, Natasha; Bischof, Matthias; Xie, Feng; O'Reilly, Daria

    2009-05-01

    Health care expenditures continue to escalate, and pressures for increased spending will continue. Health care decision makers from publicly financed systems, private insurance companies, or even from individual health care institutions, will continue to be faced with making difficult purchasing, access, and reimbursement decisions. As a result, decision makers are increasingly turning to evidence-based platforms to help control costs and make the most efficient use of existing resources. Most tools used to assist with evidence-based decision making focus on clinical outcomes. Health technology assessment (HTA) is increasing in popularity because it also considers other factors important for decision making, such as cost, social and ethical values, legal issues, and factors such as the feasibility of implementation. In some jurisdictions, HTAs have also been supplemented with primary data collection to help address uncertainty that may still exist after conducting a traditional HTA. The HTA process adopted in Ontario, Canada, is unique in that assessments are also made to determine what primary data research should be conducted and what should be collected in these studies. In this article, concerns with the traditional HTA process are discussed, followed by a description of the HTA process that has been established in Ontario, with a particular focus on the data collection program followed by the Programs for Assessment of Technology in Health Research Institute. An illustrative example is used to show how the Ontario HTA process works and the role value of information analyses plays in addressing decision uncertainty, determining research feasibility, and determining study data collection needs.

  5. Implications of model uncertainty for the practice of risk assessment

    International Nuclear Information System (INIS)

    Laskey, K.B.

    1994-01-01

    A model is a representation of a system that can be used to answer questions about the system's behavior. The term model uncertainty refers to problems in which there is no generally agreed upon, validated model that can be used as a surrogate for the system itself. Model uncertainty affects both the methodology appropriate for building models and how models should be used. This paper discusses representations of model uncertainty, methodologies for exercising and interpreting models in the presence of model uncertainty, and the appropriate use of fallible models for policy making

  6. Risk tradeoffs and public health protection

    International Nuclear Information System (INIS)

    Charnley, G.

    1998-01-01

    Full text of publication follows: over the last 25 years, the traditional command-and-control, chemical-by-chemical environmental medium-by-environmental medium, risk-by-risk approach to protecting public health from environmental risks has worked well to greatly improve the quality of our food, air, water, and workplaces, but we are now left with the more complex problems, like urban air pollution or personal dietary behavior, that a chemical-by-chemical approach is not going to solve. Because current environmental regulatory programs have curbed the 'low-hanging fruit' and because of today's emphasis on achieving risk reductions cost-effectively, new and creative public health-based approaches to risk management are needed. Since public concern about pollution-related disease become serious in the 1960's and 1970's and regulatory agencies and laws began to proliferate, the public health goals of environmental protection have been obscured. As a society, we have made a tradeoff between environmental health and public health. The public health foundation of environmental health protection has been obscured by legalistic, technical, centralized decision-making processes that have often mistaken hazard for risk. A greater focus on public health would help us to assess aggregate risks and to target risk management resources by focusing on a problem and then identifying what is causing the problem as a guide to determining how best to solve it. Most of our current approaches start with a cause and then try to eliminate it without determining the extent to which it actually may contribute to a problem, making it difficult to set priorities among risks or to evaluate the impact of risk management actions on public health. (author)

  7. Uncertainty analysis for geologic disposal of radioactive waste

    International Nuclear Information System (INIS)

    Cranwell, R.M.; Helton, J.C.

    1981-01-01

    The incorporation and representation of uncertainty in the analysis of the consequences and risks associated with the geologic disposal of high-level radioactive waste are discussed. Such uncertainty has three primary components: process modeling uncertainty, model input data uncertainty, and scenario uncertainty. The following topics are considered in connection with the preceding components: propagation of uncertainty in the modeling of a disposal site, sampling of input data for models, and uncertainty associated with model output

  8. Characterizing Epistemic Uncertainty for Launch Vehicle Designs

    Science.gov (United States)

    Novack, Steven D.; Rogers, Jim; Hark, Frank; Al Hassan, Mohammad

    2016-01-01

    NASA Probabilistic Risk Assessment (PRA) has the task of estimating the aleatory (randomness) and epistemic (lack of knowledge) uncertainty of launch vehicle loss of mission and crew risk and communicating the results. Launch vehicles are complex engineered systems designed with sophisticated subsystems that are built to work together to accomplish mission success. Some of these systems or subsystems are in the form of heritage equipment, while some have never been previously launched. For these cases, characterizing the epistemic uncertainty is of foremost importance, and it is anticipated that the epistemic uncertainty of a modified launch vehicle design versus a design of well understood heritage equipment would be greater. For reasons that will be discussed, standard uncertainty propagation methods using Monte Carlo simulation produce counter intuitive results and significantly underestimate epistemic uncertainty for launch vehicle models. Furthermore, standard PRA methods such as Uncertainty-Importance analyses used to identify components that are significant contributors to uncertainty are rendered obsolete since sensitivity to uncertainty changes are not reflected in propagation of uncertainty using Monte Carlo methods.This paper provides a basis of the uncertainty underestimation for complex systems and especially, due to nuances of launch vehicle logic, for launch vehicles. It then suggests several alternative methods for estimating uncertainty and provides examples of estimation results. Lastly, the paper shows how to implement an Uncertainty-Importance analysis using one alternative approach, describes the results, and suggests ways to reduce epistemic uncertainty by focusing on additional data or testing of selected components.

  9. Uncertainty-accounting environmental policy and management of water systems.

    Science.gov (United States)

    Baresel, Christian; Destouni, Georgia

    2007-05-15

    Environmental policies for water quality and ecosystem management do not commonly require explicit stochastic accounts of uncertainty and risk associated with the quantification and prediction of waterborne pollutant loads and abatement effects. In this study, we formulate and investigate a possible environmental policy that does require an explicit stochastic uncertainty account. We compare both the environmental and economic resource allocation performance of such an uncertainty-accounting environmental policy with that of deterministic, risk-prone and risk-averse environmental policies under a range of different hypothetical, yet still possible, scenarios. The comparison indicates that a stochastic uncertainty-accounting policy may perform better than deterministic policies over a range of different scenarios. Even in the absence of reliable site-specific data, reported literature values appear to be useful for such a stochastic account of uncertainty.

  10. Integrated frameworks for assessing and managing health risks in the context of managed aquifer recharge with river water.

    Science.gov (United States)

    Assmuth, Timo; Simola, Antti; Pitkänen, Tarja; Lyytimäki, Jari; Huttula, Timo

    2016-01-01

    Integrated assessment and management of water resources for the supply of potable water is increasingly important in light of projected water scarcity in many parts of the world. This article develops frameworks for regional-level waterborne human health risk assessment of chemical and microbiological contamination to aid water management, incorporating economic aspects of health risks. Managed aquifer recharge with surface water from a river in Southern Finland is used as an illustrative case. With a starting point in watershed governance, stakeholder concerns, and value-at-risk concepts, we merge common methods for integrative health risk analysis of contaminants to describe risks and impacts dynamically and broadly. This involves structuring analyses along the risk chain: sources-releases-environmental transport and fate-exposures-health effects-socio-economic impacts-management responses. Risks attributed to contaminants are embedded in other risks, such as contaminants from other sources, and related to benefits from improved water quality. A set of models along this risk chain in the case is presented. Fundamental issues in the assessment are identified, including 1) framing of risks, scenarios, and choices; 2) interaction of models and empirical information; 3) time dimension; 4) distributions of risks and benefits; and 5) uncertainties about risks and controls. We find that all these combine objective and subjective aspects, and involve value judgments and policy choices. We conclude with proposals for overcoming conceptual and functional divides and lock-ins to improve modeling, assessment, and management of complex water supply schemes, especially by reflective solution-oriented interdisciplinary and multi-actor deliberation. © 2015 SETAC.

  11. 2007 TOXICOLOGY AND RISK ASSESSMENT ...

    Science.gov (United States)

    EPA has announced The 2007 Toxicology and Risk Assessment Conference Cincinnati Marriott North, West Chester (Cincinnati), OHApril 23- 26, 2007 - Click to register!The Annual Toxicology and Risk Assessment Conference is a unique meeting where several Government Agencies come together to discuss toxicology and risk assessment issues that are not only of concern to the government, but also to a broader audience including academia and industry. The theme of this year's conference is Emerging Issues and Challenges in Risk Assessment and the preliminary agenda includes: Plenary Sessions and prominent speakers (tentative) include: Issues of Emerging Chemical ContaminantsUncertainty and Variability in Risk Assessment Use of Mechanistic data in IARC evaluationsParallel Sessions:Uncertainty and Variability in Dose-Response Assessment Recent Advances in Toxicity and Risk Assessment of RDX The Use of Epidemiologic Data for Risk Assessment Applications Cumulative Health Risk Assessment:

  12. Uncertainty estimation in nuclear power plant probabilistic safety assessment

    International Nuclear Information System (INIS)

    Guarro, S.B.; Cummings, G.E.

    1989-01-01

    Probabilistic Risk Assessment (PRA) was introduced in the nuclear industry and the nuclear regulatory process in 1975 with the publication of the Reactor Safety Study by the U.S. Nuclear Regulatory Commission. Almost fifteen years later, the state-of-the-art in this field has been expanded and sharpened in many areas, and about thirty-five plant-specific PRAs (Probabilistic Risk Assessments) have been performed by the nuclear utility companies or by the U.S. Nuclear Regulatory commission. Among the areas where the most evident progress has been made in PRA and PSA (Probabilistic Safety Assessment, as these studies are more commonly referred to in the international community outside the U.S.) is the development of a consistent framework for the identification of sources of uncertainty and the estimation of their magnitude as it impacts various risk measures. Techniques to propagate uncertainty in reliability data through the risk models and display its effect on the top level risk estimates were developed in the early PRAs. The Seismic Safety Margin Research Program (SSMRP) study was the first major risk study to develop an approach to deal explicitly with uncertainty in risk estimates introduced not only by uncertainty in component reliability data, but by the incomplete state of knowledge of the assessor(s) with regard to basic phenomena that may trigger and drive a severe accident. More recently NUREG-1150, another major study of reactor risk sponsored by the NRC, has expanded risk uncertainty estimation and analysis into the realm of model uncertainty related to the relatively poorly known post-core-melt phenomena which determine the behavior of the molten core and of the rector containment structures

  13. Decision-making under risk and uncertainty

    International Nuclear Information System (INIS)

    Gatev, G.I.

    2006-01-01

    Fuzzy sets and interval analysis tools to make computations and solve optimisation problems are presented. Fuzzy and interval extensions of Decision Theory criteria for decision-making under parametric uncertainty of prior information (probabilities, payoffs) are developed. An interval probability approach to the mean-value criterion is proposed. (author)

  14. A study on the assessment of safety culture impacts on risk of nuclear power plants using common uncertainty source model

    International Nuclear Information System (INIS)

    Lee, Yong Suk; Bang, Young Suk; Chung, Chang Hyun; Jeong, Ji Hwan

    2004-01-01

    Since International Safety Advisory Group (INSAG) introduced term 'safety culture', it has been widely recognized that safety culture has an important role in safety of nuclear power plants. Research on the safety culture can be divided in the following two parts. 1) Assessment of safety culture (by interview, questionnaire, etc.) 2) Assessment of link between safety culture and safety of nuclear power plants. There is a substantial body of literature that addresses the first part, but there is much less work that addresses the second part. To address the second part, most work focused on the development of model incorporating safety culture into Probabilistic Safety Assessment (PSA). One of the most advanced methodology in the area of incorporating safety culture quantitatively into PSA is System Dynamics (SD) model developed by Kwak et al. It can show interactions among various factors which affect employees' productivity and job quality. Also various situations in nuclear power plant can be simulated and time-dependent risk can be recalculated with this model. But this model does not consider minimal cut set (MCS) dependency and uncertainty of risk. Another well-known methodology is Work Process Analysis Model (WPAM) developed by Davoudian. It considers MCS dependency by modifying conditional probability values using SLI methodology. But we found that the modified conditional probability values in WPAM are somewhat artificial and have no sound basis. WPAM tend to overestimate conditional probability of hardware failure, because it uses SLI methodology which is normally used in Human Reliability Analysis (HRA). WPAM also does not consider uncertainty of risk. In this study, we proposed methodology to incorporate safety culture into PSA quantitatively that can deal with MCS dependency and uncertainty of risk by applying the Common Uncertainty Source (CUS) model developed by Zhang. CUS is uncertainty source that is common to basic events, and this can be physical

  15. Health risks in perspective: Judging health risks of energy technologies. Revision 5/94

    Energy Technology Data Exchange (ETDEWEB)

    Rowe, M.D.

    1992-09-01

    The purpose of this report is to provide perspective on the various risks to which man is routinely exposed. It serves as a basis for understanding the meaning of quantitative risk estimates and for comparing new or newly-discovered risks with other, better-understood risks. Specific emphasis is placed on health risks of energy technologies. This report is not a risk assessment; nor does it contain instructions on how to do a risk assessment. Rather, it provides background information on how most of us think about risks and why it is difficult to do it rationally, it provides a philosophy and data with which to do a better job of judging risks more rationally, and it provides an overview of where risks of energy technologies fit within the spectrum of all risks. Much of the quantitative information provided here is on relative risk of dying of various causes. This is not because risk of dying is seen as the most important kind of risk, but because the statistics on mortality rates by cause are the highest quality data available on health risks in the general population.

  16. Uncertainty in the Shale Gas Debate: Views From the Science–Policymaking Interface

    Directory of Open Access Journals (Sweden)

    Constantin Marius PROFIROIU

    2015-10-01

    Full Text Available Shale gas involves a technology which is a controversial method of energy production mainly because there are uncertainties about the possible environmental and human health impacts. The article aims to identify the level of knowledge in relation to the impact of environmental risks attached to shale gas exploitation in the academic and scientifi c community. It does so by employing the expert elicitation approach which has the benefi t of quantifying the judgment of individual experts. We have revealed a consistency among researchers in assessing the level of uncertainty of the main environmental risks and a preferred policy option in dealing with uncertainty, a vow for improved transparency, openness and ease of access to information. Shale gas policy-making in Europe needs a science- based approach as science informs policy by delivering objective and reliable knowledge. The article concludes that developing a comprehensive approach based on scientifi c data and an appropriate regulatory framework will provide a path forward for the future development of contested policies like shale gas.

  17. Metrology and process control: dealing with measurement uncertainty

    Science.gov (United States)

    Potzick, James

    2010-03-01

    Metrology is often used in designing and controlling manufacturing processes. A product sample is processed, some relevant property is measured, and the process adjusted to bring the next processed sample closer to its specification. This feedback loop can be remarkably effective for the complex processes used in semiconductor manufacturing, but there is some risk involved because measurements have uncertainty and product specifications have tolerances. There is finite risk that good product will fail testing or that faulty product will pass. Standard methods for quantifying measurement uncertainty have been presented, but the question arises: how much measurement uncertainty is tolerable in a specific case? Or, How does measurement uncertainty relate to manufacturing risk? This paper looks at some of the components inside this process control feedback loop and describes methods to answer these questions.

  18. Securitization of residential solar photovoltaic assets: Costs, risks and uncertainty

    International Nuclear Information System (INIS)

    Alafita, T.; Pearce, J.M.

    2014-01-01

    Limited access to low-cost financing is an impediment to high-velocity technological diffusion and high grid penetration of solar photovoltaic (PV) technology. Securitization of solar assets provides a potential solution to this problem. This paper assesses the viability of solar asset-backed securities (ABS) as a lower cost financing mechanism and identifies policies that could facilitate implementation of securitization. First, traditional solar financing is examined to provide a baseline for cost comparisons. Next, the securitization process is modeled. The model enables identification of several junctures at which risk and uncertainty influence costs. Next, parameter values are assigned and used to generate cost estimates. Results show that, under reasonable assumptions, securitization of solar power purchase agreements (PPA) can significantly reduce project financing costs, suggesting that securitization is a viable mechanism for improving the financing of PV projects. The clear impediment to the successful launch of a solar ABS is measuring and understanding the riskiness of underlying assets. This study identifies three classes of policy intervention that lower the cost of ABS by reducing risk or by improving the measurement of risk: (i) standardization of contracts and the contracting process, (ii) improved access to contract and equipment performance data, and (iii) geographic diversification. - Highlights: • Limited access to low-cost financing is hampering penetration of solar PV. • Solar asset-backed securities (ABS) provide a low cost financing mechanism. • Results for securitization of solar leases and power purchase agreements (PPA). • Securitization can significantly reduce project financing costs. • Identifies policy intervention that lower cost of ABS by reducing risk

  19. Risk-Based Management of Contaminated Groundwater: The Role of Geologic Heterogeneity, Exposure and Cancer Risk in Determining the Performance of Aquifer Remediation

    International Nuclear Information System (INIS)

    Maxwell, R.M.; Carle, S.F.; Tompson, A.F.B.

    2000-01-01

    The effectiveness of aquifer remediation is typically expressed in terms of a reduction in contaminant concentrations relative to a regulated maximum contaminant level (MCL), and is usually confined by sparse monitoring data and/or simple model calculations. Here, the effectiveness of remediation is examined from a risk-based perspective that goes beyond the traditional MCL concept. A methodology is employed to evaluate the health risk to individuals exposed to contaminated household water that is produced from groundwater. This approach explicitly accounts for differences in risk arising from variability in individual physiology and water use, the uncertainty in estimating chemical carcinogenesis for different individuals, and the uncertainties and variability in contaminant concentrations within groundwater. A hypothetical contamination scenario is developed as a case study in a saturated, alluvial aquifer underlying a real Superfund site. A baseline (unremediated) human exposure and health risk scenario, as induced by contaminated groundwater pumped from this site, is predicted and compared with a similar estimate based upon pump-and-treat exposure intervention. The predicted reduction in risk in the remediation scenario is not an equitable one-that is, it is not uniform to all individuals within a population and varies according to the level of uncertainty in prediction. The importance of understanding the detailed hydrogeologic connections that are established in the heterogeneous geologic regime between the contaminated source, municipal receptors, and remediation wells, and its relationship to this uncertainty is demonstrated. Using two alternative pumping rates, we develop cost-benefit curves based upon reduced exposure and risk to different individuals within the population, under the presence of uncertainty

  20. Managing uncertainty: healthcare professionals' meanings regarding the HPV vaccine.

    Science.gov (United States)

    Todorova, Irina; Alexandrova-Karamanova, Anna; Panayotova, Yulia; Dimitrova, Elitsa; Kotzeva, Tatyana

    2014-02-01

    New preventive technologies such as vaccines offer insight into psychological, social, and cultural landscapes. Providers have a key role in parents' decisions for vaccinating their children. Yet, perspectives from providers regarding the human papillomavirus (HPV) vaccine, or vaccination in general, are rarely sought Our objective in this paper is to understand how the HPV vaccine is perceived by health care providers and the multiple contextual meanings it elicits. We conducted interviews with 20 health care professionals in Bulgaria about their attitudes and practices related to HPV vaccination and their recommendations for policies. The verbatim-transcribed interviews were analyzed through narrative analysis, with a special focus on language. We illustrate providers' contradictory and contextualized constructions of the vaccine and the narrative strategies they use to manage any uncertainty it elicits. These include being advocates and missionaries for preventive health, confirming their trust in the medical profession and professional organizations, challenging patients' concerns with rational explanations, normalizing the risk of medical innovations, and avoiding the sexual nature of HPV transmission. The introduction of a vaccine to prevent HPV infection, and by implication, possibly cervical and other cancers, created hope, and at the same time, intensified confusion and uncertainty. Providers have been frustrated for years with the rising mortality from cervical cancer in Bulgaria, and their perceived powerlessness in affecting this. HPV vaccination, on the other hand, seems relatively simple and "taming uncertainty" positions them as instrumental in limiting (or even eliminating) morbidity and mortality in future generations.

  1. Assessment of uncertainties in core melt phenomenology and their impact on risk at the Z/IP facilities

    International Nuclear Information System (INIS)

    Pratt, W.T.; Ludewig, H.; Bari, R.A.; Meyer, J.F.

    1983-01-01

    An evaluation of core meltdown accidents in the Z/IP facilities has been performed. Containment event trees have been developed to relate the progression of a given accident to various potential containment building failure modes. An extensive uncertainty analysis related to core melt phenomenology has been performed. A major conclusion of the study is that large variations in parameters associated with major phenomenological uncertainties have a relatively minor impact on risk when external initiators are considered. This is due to the inherent capability fo the Z/IP containment buildings to contain a wide range of core meltdown accidents. 12 references, 2 tables

  2. Radon contents in groundwater and the uncertainty related to risk assessment

    Energy Technology Data Exchange (ETDEWEB)

    Fukui, Masami [Kyoto Univ. (Japan)

    1997-02-01

    The United States has proposed 11 Bq/l (300 pCi/l) as the maximum contaminant levels (MCLs) of radon. Japan has not set up the standards for drinking water. The problems about evaluation of effects of radon on organism and MCLs of radon in groundwater and drinking water in 12 countries were reported. The local area content the high concentrations of radon, but generally it`s low levels were observed in Nigeria, China and Mexico. The countries which content high concentration of radon were Greek, Slovakia, Bornholm Island and Scotland. There are high and low concentration area in US and Japan. I proposed an uncertainty scheme on risk assessment for the exposure by radon. (S.Y.)

  3. Public health and economic risk assessment of waterborne contaminants and pathogens in Finland.

    Science.gov (United States)

    Juntunen, Janne; Meriläinen, Päivi; Simola, Antti

    2017-12-01

    This study shows that a variety of mathematical modeling techniques can be applied in a comprehensive assessment of the risks involved in drinking water production. In order to track the effects from water sources to the end consumers, we employed four models from different fields of study. First, two models of the physical environment, which track the movement of harmful substances from the sources to the water distribution. Second, a statistical quantitative microbial risk assessment (QMRA) to assess the public health risks of the consumption of such water. Finally, a regional computable general equilibrium (CGE) model to assess the economic effects of increased illnesses. In order to substantiate our analysis, we used an illustrative case of a recently built artificial recharge system in Southern Finland that provides water for a 300,000 inhabitant area. We examine the effects of various chemicals and microbes separately. Our economic calculations allow for direct effects on labor productivity due to absenteeism, increased health care expenditures and indirect effects for local businesses. We found that even a considerable risk has no notable threat to public health and thus barely measurable economic consequences. Any epidemic is likely to spread widely in the urban setting we examined, but is also going to be short-lived in both public health and economic terms. Our estimate for the ratio of total and direct effects is 1.4, which indicates the importance of general equilibrium effects. Furthermore, the total welfare loss is 2.4 times higher than the initial productivity loss. The major remaining uncertainty in the economic assessment is the indirect effects. Copyright © 2017 Elsevier B.V. All rights reserved.

  4. Optimization Under Uncertainty of Site-Specific Turbine Configurations

    Science.gov (United States)

    Quick, J.; Dykes, K.; Graf, P.; Zahle, F.

    2016-09-01

    Uncertainty affects many aspects of wind energy plant performance and cost. In this study, we explore opportunities for site-specific turbine configuration optimization that accounts for uncertainty in the wind resource. As a demonstration, a simple empirical model for wind plant cost of energy is used in an optimization under uncertainty to examine how different risk appetites affect the optimal selection of a turbine configuration for sites of different wind resource profiles. If there is unusually high uncertainty in the site wind resource, the optimal turbine configuration diverges from the deterministic case and a generally more conservative design is obtained with increasing risk aversion on the part of the designer.

  5. Application of probability distributions for quantifying uncertainty in radionuclide source terms for Seabrook risk assessment

    International Nuclear Information System (INIS)

    Walker, D.H.; Savin, N.L.

    1985-01-01

    The calculational models developed for the Reactor Safety Study (RSS) have traditionally been used to generate 'point estimate values' for radionuclide release to the environment for nuclear power plant risk assessments. The point estimate values so calculated are acknowledged by most knowledgeable individuals to be conservatively high. Further, recent evaluations of the overall uncertainties in the various components that make up risk estimates for nuclear electric generating stations show that one of the large uncertainties is associated with the magnitude of the radionuclide release to the environment. In the approach developed for the RSS, values for fission product release from the fuel are derived from data obtained from small experiments. A reappraisal of the RSS release fractions was published in 1981 in NUREG-0772. Estimates of fractional releases from fuel are similar to those of the RSS. In the RSS approach, depletion during transport from the core (where the fission products are released) to the containment is assumed to be zero for calculation purposes. In the containment, the CORRAL code is applied to calculate radioactivity depletion by containment processes and to calculate the quantity and timing of release to the environment

  6. Uncertainty Quantification in High Throughput Screening ...

    Science.gov (United States)

    Using uncertainty quantification, we aim to improve the quality of modeling data from high throughput screening assays for use in risk assessment. ToxCast is a large-scale screening program that analyzes thousands of chemicals using over 800 assays representing hundreds of biochemical and cellular processes, including endocrine disruption, cytotoxicity, and zebrafish development. Over 2.6 million concentration response curves are fit to models to extract parameters related to potency and efficacy. Models built on ToxCast results are being used to rank and prioritize the toxicological risk of tested chemicals and to predict the toxicity of tens of thousands of chemicals not yet tested in vivo. However, the data size also presents challenges. When fitting the data, the choice of models, model selection strategy, and hit call criteria must reflect the need for computational efficiency and robustness, requiring hard and somewhat arbitrary cutoffs. When coupled with unavoidable noise in the experimental concentration response data, these hard cutoffs cause uncertainty in model parameters and the hit call itself. The uncertainty will then propagate through all of the models built on the data. Left unquantified, this uncertainty makes it difficult to fully interpret the data for risk assessment. We used bootstrap resampling methods to quantify the uncertainty in fitting models to the concentration response data. Bootstrap resampling determines confidence intervals for

  7. Failure probability under parameter uncertainty.

    Science.gov (United States)

    Gerrard, R; Tsanakas, A

    2011-05-01

    In many problems of risk analysis, failure is equivalent to the event of a random risk factor exceeding a given threshold. Failure probabilities can be controlled if a decisionmaker is able to set the threshold at an appropriate level. This abstract situation applies, for example, to environmental risks with infrastructure controls; to supply chain risks with inventory controls; and to insurance solvency risks with capital controls. However, uncertainty around the distribution of the risk factor implies that parameter error will be present and the measures taken to control failure probabilities may not be effective. We show that parameter uncertainty increases the probability (understood as expected frequency) of failures. For a large class of loss distributions, arising from increasing transformations of location-scale families (including the log-normal, Weibull, and Pareto distributions), the article shows that failure probabilities can be exactly calculated, as they are independent of the true (but unknown) parameters. Hence it is possible to obtain an explicit measure of the effect of parameter uncertainty on failure probability. Failure probability can be controlled in two different ways: (1) by reducing the nominal required failure probability, depending on the size of the available data set, and (2) by modifying of the distribution itself that is used to calculate the risk control. Approach (1) corresponds to a frequentist/regulatory view of probability, while approach (2) is consistent with a Bayesian/personalistic view. We furthermore show that the two approaches are consistent in achieving the required failure probability. Finally, we briefly discuss the effects of data pooling and its systemic risk implications. © 2010 Society for Risk Analysis.

  8. Risk assessment and uncertainty of the shrimp trawl fishery in the Gulf of California considering environmental variability

    Directory of Open Access Journals (Sweden)

    Luis César Almendarez-Hernández

    2015-09-01

    Full Text Available The shrimp fishery off the Mexican Pacific coast is the country's most important fishery from the economic standpoint. However, it faces serious problems, including the fleet's overcapitalization and age, in addition to the environmental variability that affects the size of catches. Thus, this activity depends on a variety of factors that add uncertainty to the profitability of fishing vessels. This study aims to estimate the probability of success and economic risk of "type vessels" under two different environmental variability scenarios in the Gulf of California. The results from the economic simulation pointed to the vessel type used in Guaymas (Sonora as the most efficient one under a neutral climate change scenario, showing a homogeneous behaviour in physical characteristics and mode of operation. By contrast, under a scenario of a monotonic rise in sea surface temperature, the shrimp fishery faces a greater risk of incurring economic losses. The simulated climate behaviour scenarios revealed that the activity involves a moderate economic profitability under the neutral scenario; however, under the warming scenario, profitability may be low or even nil due to the risks and uncertainty resulting from the influence of environmental phenomena.

  9. Uncertainty analysis techniques

    International Nuclear Information System (INIS)

    Marivoet, J.; Saltelli, A.; Cadelli, N.

    1987-01-01

    The origin of the uncertainty affecting Performance Assessments, as well as their propagation to dose and risk results is discussed. The analysis is focused essentially on the uncertainties introduced by the input parameters, the values of which may range over some orders of magnitude and may be given as probability distribution function. The paper briefly reviews the existing sampling techniques used for Monte Carlo simulations and the methods for characterizing the output curves, determining their convergence and confidence limits. Annual doses, expectation values of the doses and risks are computed for a particular case of a possible repository in clay, in order to illustrate the significance of such output characteristics as the mean, the logarithmic mean and the median as well as their ratios. The report concludes that provisionally, due to its better robustness, such estimation as the 90th percentile may be substituted to the arithmetic mean for comparison of the estimated doses with acceptance criteria. In any case, the results obtained through Uncertainty Analyses must be interpreted with caution as long as input data distribution functions are not derived from experiments reasonably reproducing the situation in a well characterized repository and site

  10. A nonparametric approach to medical survival data: Uncertainty in the context of risk in mortality analysis

    International Nuclear Information System (INIS)

    Janurová, Kateřina; Briš, Radim

    2014-01-01

    Medical survival right-censored data of about 850 patients are evaluated to analyze the uncertainty related to the risk of mortality on one hand and compare two basic surgery techniques in the context of risk of mortality on the other hand. Colorectal data come from patients who underwent colectomy in the University Hospital of Ostrava. Two basic surgery operating techniques are used for the colectomy: either traditional (open) or minimally invasive (laparoscopic). Basic question arising at the colectomy operation is, which type of operation to choose to guarantee longer overall survival time. Two non-parametric approaches have been used to quantify probability of mortality with uncertainties. In fact, complement of the probability to one, i.e. survival function with corresponding confidence levels is calculated and evaluated. First approach considers standard nonparametric estimators resulting from both the Kaplan–Meier estimator of survival function in connection with Greenwood's formula and the Nelson–Aalen estimator of cumulative hazard function including confidence interval for survival function as well. The second innovative approach, represented by Nonparametric Predictive Inference (NPI), uses lower and upper probabilities for quantifying uncertainty and provides a model of predictive survival function instead of the population survival function. The traditional log-rank test on one hand and the nonparametric predictive comparison of two groups of lifetime data on the other hand have been compared to evaluate risk of mortality in the context of mentioned surgery techniques. The size of the difference between two groups of lifetime data has been considered and analyzed as well. Both nonparametric approaches led to the same conclusion, that the minimally invasive operating technique guarantees the patient significantly longer survival time in comparison with the traditional operating technique

  11. Uncertainty, joint uncertainty, and the quantum uncertainty principle

    International Nuclear Information System (INIS)

    Narasimhachar, Varun; Poostindouz, Alireza; Gour, Gilad

    2016-01-01

    Historically, the element of uncertainty in quantum mechanics has been expressed through mathematical identities called uncertainty relations, a great many of which continue to be discovered. These relations use diverse measures to quantify uncertainty (and joint uncertainty). In this paper we use operational information-theoretic principles to identify the common essence of all such measures, thereby defining measure-independent notions of uncertainty and joint uncertainty. We find that most existing entropic uncertainty relations use measures of joint uncertainty that yield themselves to a small class of operational interpretations. Our notion relaxes this restriction, revealing previously unexplored joint uncertainty measures. To illustrate the utility of our formalism, we derive an uncertainty relation based on one such new measure. We also use our formalism to gain insight into the conditions under which measure-independent uncertainty relations can be found. (paper)

  12. Human health risk assessment in relation to environmental pollution of two artificial freshwater lakes in The Netherlands.

    Science.gov (United States)

    Albering, H J; Rila, J P; Moonen, E J; Hoogewerff, J A; Kleinjans, J C

    1999-01-01

    A human health risk assessment has been performed in relation to recreational activities on two artificial freshwater lakes along the river Meuse in The Netherlands. Although the discharges of contaminants into the river Meuse have been reduced in the last decades, which is reflected in decreasing concentrations of pollutants in surface water and suspended matter, the levels in sediments are more persistent. Sediments of the two freshwater lakes appear highly polluted and may pose a health risk in relation to recreational activities. To quantify health risks for carcinogenic (e.g., polycyclic aromatic hydrocarbons) as well as noncarcinogenic compounds (e.g., heavy metals), an exposure assessment model was used. First, we used a standard model that solely uses data on sediment pollution as the input parameter, which is the standard procedure in sediment quality assessments in The Netherlands. The highest intake appeared to be associated with the consumption of contaminated fish and resulted in a health risk for Pb and Zn (hazard index exceeded 1). For the other heavy metals and for benzo(a)pyrene, the total averaged exposure levels were below levels of concern. Secondly, input data for a more location-specific calculation procedure were provided via analyses of samples from sediment, surface water, and suspended matter. When these data (concentrations in surface water) were taken into account, the risk due to consumption of contaminated fish decreased by more than two orders of magnitude and appeared to be negligible. In both exposure assessments, many assumptions were made that contribute to a major degree to the uncertainty of this risk assessment. However, this health risk evaluation is useful as a screening methodology for assessing the urgency of sediment remediation actions.

  13. ENTERPRISE OPERATION PLANNING IN THE CONDITIONS OF RISK AND UNCERTAINTY IN THE EXTERNAL AND INTERNAL ENVIRONMENT

    Directory of Open Access Journals (Sweden)

    Titov V. V.

    2017-09-01

    Full Text Available Optimization of the enterprise activity planning taking into account the risk and uncertainty of the external and internal environment is a complex scientific and methodological problem. Its solution is important for the planning practice. Therefore, the relevance of this research topic is beyond doubt. Planning is based on the use of a multilevel system of models. At the top level, the achievement of key strategic indicators is ensured by the development and implementation of innovations, mainly related to the planning of the release of new high-tech products. However, it is at this level that the risks and uncertainties have the greatest impact on the planning processes for the development, production and marketing of new products. In the scientific literature it is proposed to use the stochastic graphs with returns for this purpose. This idea is also supported in this work. However, the implementation of such an idea requires additional methodological developments and quantitative calculations. The coordination of strategic decisions with tactical plans is based on the idea of eliminating the economic and other risks associated with the economic activity of the enterprise in tactical planning, by creating the stochastic reserves based on the implementation of additional innovations that ensure the receipt of above-target sales volumes, profits and other indicators of the strategic plan. The organization of operational management of production is represented by an iterative, sliding process (reducing risks in production, which is realized taking into account the limitations of tactical control.

  14. County-Level Climate Uncertainty for Risk Assessments: Volume 18 Appendix Q - Historical Maximum Near-Surface Wind Speed.

    Energy Technology Data Exchange (ETDEWEB)

    Backus, George A.; Lowry, Thomas Stephen; Jones, Shannon M; Walker, La Tonya Nicole; Roberts, Barry L; Malczynski, Leonard A.

    2017-06-01

    This report uses the CMIP5 series of climate model simulations to produce country- level uncertainty distributions for use in socioeconomic risk assessments of climate change impacts. It provides appropriate probability distributions, by month, for 169 countries and autonomous-areas on temperature, precipitation, maximum temperature, maximum wind speed, humidity, runoff, soil moisture and evaporation for the historical period (1976-2005), and for decadal time periods to 2100. It also provides historical and future distributions for the Arctic region on ice concentration, ice thickness, age of ice, and ice ridging in 15-degree longitude arc segments from the Arctic Circle to 80 degrees latitude, plus two polar semicircular regions from 80 to 90 degrees latitude. The uncertainty is meant to describe the lack of knowledge rather than imprecision in the physical simulation because the emphasis is on unfalsified risk and its use to determine potential socioeconom ic impacts. The full report is contained in 27 volumes.

  15. County-Level Climate Uncertainty for Risk Assessments: Volume 4 Appendix C - Historical Maximum Near-Surface Air Temperature.

    Energy Technology Data Exchange (ETDEWEB)

    Backus, George A.; Lowry, Thomas Stephen; Jones, Shannon M; Walker, La Tonya Nicole; Roberts, Barry L; Malczynski, Leonard A.

    2017-06-01

    This report uses the CMIP5 series of climate model simulations to produce country- level uncertainty distributions for use in socioeconomic risk assessments of climate change impacts. It provides appropriate probability distributions, by month, for 169 countries and autonomous-areas on temperature, precipitation, maximum temperature, maximum wind speed, humidity, runoff, soil moisture and evaporation for the historical period (1976-2005), and for decadal time periods to 2100. It also provides historical and future distributions for the Arctic region on ice concentration, ice thickness, age of ice, and ice ridging in 15-degree longitude arc segments from the Arctic Circle to 80 degrees latitude, plus two polar semicircular regions from 80 to 90 degrees latitude. The uncertainty is meant to describe the lack of knowledge rather than imprecision in the physical simulation because the emphasis is on unfalsified risk and its use to determine potential socioeconomic impacts. The full report is contained in 27 volumes.

  16. County-Level Climate Uncertainty for Risk Assessments: Volume 6 Appendix E - Historical Minimum Near-Surface Air Temperature.

    Energy Technology Data Exchange (ETDEWEB)

    Backus, George A.; Lowry, Thomas Stephen; Jones, Shannon M; Walker, La Tonya Nicole; Roberts, Barry L; Malczynski, Leonard A.

    2017-06-01

    This report uses the CMIP5 series of climate model simulations to produce country- level uncertainty distributions for use in socioeconomic risk assessments of climate change impacts. It provides appropriate probability distributions, by month, for 169 countries and autonomous-areas on temperature, precipitation, maximum temperature, maximum wind speed, humidity, runoff, soil moisture and evaporation for the historical period (1976-2005), and for decadal time periods to 2100. It also provides historical and future distributions for the Arctic region on ice concentration, ice thickness, age of ice, and ice ridging in 15-degree longitude arc segments from the Arctic Circle to 80 degrees latitude, plus two polar semicircular regions from 80 to 90 degrees latitude. The uncertainty is meant to describe the lack of knowledge rather than imprecision in the physical simulation because the emphasis is on unfalsified risk and its use to determine potential socioeconomic impacts. The full report is contained in 27 volumes.

  17. [Uncertainty characterization approaches for ecological risk assessment of polycyclic aromatic hydrocarbon in Taihu Lake].

    Science.gov (United States)

    Guo, Guang-Hui; Wu, Feng-Chang; He, Hong-Ping; Feng, Cheng-Lian; Zhang, Rui-Qing; Li, Hui-Xian

    2012-04-01

    Probabilistic approaches, such as Monte Carlo Sampling (MCS) and Latin Hypercube Sampling (LHS), and non-probabilistic approaches, such as interval analysis, fuzzy set theory and variance propagation, were used to characterize uncertainties associated with risk assessment of sigma PAH8 in surface water of Taihu Lake. The results from MCS and LHS were represented by probability distributions of hazard quotients of sigma PAH8 in surface waters of Taihu Lake. The probabilistic distribution of hazard quotient were obtained from the results of MCS and LHS based on probabilistic theory, which indicated that the confidence intervals of hazard quotient at 90% confidence level were in the range of 0.000 18-0.89 and 0.000 17-0.92, with the mean of 0.37 and 0.35, respectively. In addition, the probabilities that the hazard quotients from MCS and LHS exceed the threshold of 1 were 9.71% and 9.68%, respectively. The sensitivity analysis suggested the toxicity data contributed the most to the resulting distribution of quotients. The hazard quotient of sigma PAH8 to aquatic organisms ranged from 0.000 17 to 0.99 using interval analysis. The confidence interval was (0.001 5, 0.016 3) at the 90% confidence level calculated using fuzzy set theory, and the confidence interval was (0.000 16, 0.88) at the 90% confidence level based on the variance propagation. These results indicated that the ecological risk of sigma PAH8 to aquatic organisms were low. Each method has its own set of advantages and limitations, which was based on different theory; therefore, the appropriate method should be selected on a case-by-case to quantify the effects of uncertainties on the ecological risk assessment. Approach based on the probabilistic theory was selected as the most appropriate method to assess the risk of sigma PAH8 in surface water of Taihu Lake, which provided an important scientific foundation of risk management and control for organic pollutants in water.

  18. Risk aversion and uncertainty in cost-effectiveness analysis: the expected-utility, moment-generating function approach.

    Science.gov (United States)

    Elbasha, Elamin H

    2005-05-01

    The availability of patient-level data from clinical trials has spurred a lot of interest in developing methods for quantifying and presenting uncertainty in cost-effectiveness analysis (CEA). Although the majority has focused on developing methods for using sample data to estimate a confidence interval for an incremental cost-effectiveness ratio (ICER), a small strand of the literature has emphasized the importance of incorporating risk preferences and the trade-off between the mean and the variance of returns to investment in health and medicine (mean-variance analysis). This paper shows how the exponential utility-moment-generating function approach is a natural extension to this branch of the literature for modelling choices from healthcare interventions with uncertain costs and effects. The paper assumes an exponential utility function, which implies constant absolute risk aversion, and is based on the fact that the expected value of this function results in a convenient expression that depends only on the moment-generating function of the random variables. The mean-variance approach is shown to be a special case of this more general framework. The paper characterizes the solution to the resource allocation problem using standard optimization techniques and derives the summary measure researchers need to estimate for each programme, when the assumption of risk neutrality does not hold, and compares it to the standard incremental cost-effectiveness ratio. The importance of choosing the correct distribution of costs and effects and the issues related to estimation of the parameters of the distribution are also discussed. An empirical example to illustrate the methods and concepts is provided. Copyright 2004 John Wiley & Sons, Ltd

  19. Risk indices in comparative risk assessment studies

    International Nuclear Information System (INIS)

    Hubert, P.

    1984-01-01

    More than a decade ago the development of comparative risk assessment studies aroused overwhelming interest. There was no doubt that data on the health and safety aspects of energy systems would greatly benefit, or even end, the debate on nuclear energy. Although such attempts are still strongly supported, the rose-coloured expectations of the early days have faded. The high uncertainties, and the contradictory aspect, of the first results might explain this evolution. The loose connection between the range of computed risk indices and the questions on which the debate was focused is another reason for this decline in interest. Important research work is being carried out aiming at reducing the different kinds of uncertainties. Rather than the uncertainties, the paper considers the meaning of available risk indices and proposes more significant indices with respect to the goals of risk assessment. First, the indices which are of frequent use in comparative studies are listed. The stress is put on a French comparative study from which most examples are drawn. Secondly, the increase in magnitude of the indices and the decrease in the attributability of the risk to a given system is shown to be a consequence of the trend towards more comprehensive analyses. Thirdly, the ambiguity of such indices as the collective occupational risk is underlined, and a possible solution is suggested. Whenever risk assessments are related to pragmatic decision making problems it is possible to find satisfactory risk indices. The development of cost-effectiveness analyses and the proposals for quantitative safety goals clearly demonstrate this point. In the field of comparison of social impacts some proposals are made, but there remain some gaps still to be filled. (author)

  20. Health Risk Behavior in Foster Youth

    Science.gov (United States)

    Gramkowski, Bridget; Kools, Susan; Paul, Steven; Boyer, Cherrie; Monasterio, Erica; Robbins, Nancy

    2010-01-01

    Problem Adolescent health problems are predominantly caused by risk behavior. Foster adolescents have disproportionately poor health; therefore identification of risk behavior is critical. Method A secondary analysis of data from a larger study investigated the health risk behavior of 56 foster youth using the CHIP-AE. Findings Foster youth had some increased risk behavior. Younger adolescents and those in kinship care had less risky behavior. Youth had more risk behavior when: in group homes, parental death, histories of physical or emotional abuse, or history of attempted suicide. Conclusions These results point to areas of strength and vulnerability in foster youth. PMID:19490278

  1. Reliability, resilience and vulnerability criteria for the evaluation of time-dependent health risks: A hypothetical case study of wellhead protection

    Science.gov (United States)

    Rodak, C. M.; Silliman, S. E.; Bolster, D.

    2012-12-01

    A hypothetical case study of groundwater contaminant protection was carried out using time-dependent health risk calculations. The case study focuses on a hypothetical zoning project for parcels of land around a well field in northern Indiana, where the control of cancer risk relative to a mandated cancer risk threshold is of concern in the management strategy. Within our analysis, we include both uncertainty in the subsurface transport and variability in population behavior in the calculation of time-dependent health risks. From these results we introduce risk maps, a visual representation of the probability of an unacceptable health risk as a function of population behavior and the time at which exposure to the contaminant begins. We also evaluate the time-dependent risks with three criteria from water resource literature: reliability, resilience, and vulnerability (RRV). With respect to health risk from a groundwater well, the three criteria determine: the probability that a well produces safe water (reliability), the probability that a contaminated well returns to an uncontaminated state within a specified time interval (resilience), and the overall severity in terms of health impact of the contamination at a well head (vulnerability). The results demonstrate that the distributions of RRV values for each parcel of land are linked to the time-dependent concentration profile of the contaminant at the well, and the toxicological characteristics of the contaminant. The proposed time-dependent risk calculation expands on current techniques to include a continuous exposure start time, capable of reproducing the maximum risk while providing information on the severity and duration of health risks. Overall this study suggests that, especially in light of the inherent complexity of health-groundwater systems, RRV are viable criteria for relatively simple and effective evaluation of time-dependent health risk. It is argued that the RRV approach, as applied to

  2. Cumulative Risk Assessment (CRA): transforming the way we assess health risks.

    Science.gov (United States)

    Williams, Pamela R D; Dotson, G Scott; Maier, Andrew

    2012-10-16

    Human health risk assessments continue to evolve and now focus on the need for cumulative risk assessment (CRA). CRA involves assessing the combined risk from coexposure to multiple chemical and nonchemical stressors for varying health effects. CRAs are broader in scope than traditional chemical risk assessments because they allow for a more comprehensive evaluation of the interaction between different stressors and their combined impact on human health. Future directions of CRA include greater emphasis on local-level community-based assessments; integrating environmental, occupational, community, and individual risk factors; and identifying and implementing common frameworks and risk metrics for incorporating multiple stressors.

  3. Conflict or Caveats? Effects of Media Portrayals of Scientific Uncertainty on Audience Perceptions of New Technologies.

    Science.gov (United States)

    Binder, Andrew R; Hillback, Elliott D; Brossard, Dominique

    2016-04-01

    Research indicates that uncertainty in science news stories affects public assessment of risk and uncertainty. However, the form in which uncertainty is presented may also affect people's risk and uncertainty assessments. For example, a news story that features an expert discussing both what is known and what is unknown about a topic may convey a different form of scientific uncertainty than a story that features two experts who hold conflicting opinions about the status of scientific knowledge of the topic, even when both stories contain the same information about knowledge and its boundaries. This study focuses on audience uncertainty and risk perceptions regarding the emerging science of nanotechnology by manipulating whether uncertainty in a news story about potential risks is attributed to expert sources in the form of caveats (individual uncertainty) or conflicting viewpoints (collective uncertainty). Results suggest that the type of uncertainty portrayed does not impact audience feelings of uncertainty or risk perceptions directly. Rather, the presentation of the story influences risk perceptions only among those who are highly deferent to scientific authority. Implications for risk communication theory and practice are discussed. © 2015 Society for Risk Analysis.

  4. Sunway Medical Laboratory Quality Control Plans Based on Six Sigma, Risk Management and Uncertainty.

    Science.gov (United States)

    Jairaman, Jamuna; Sakiman, Zarinah; Li, Lee Suan

    2017-03-01

    Sunway Medical Centre (SunMed) implemented Six Sigma, measurement uncertainty, and risk management after the CLSI EP23 Individualized Quality Control Plan approach. Despite the differences in all three approaches, each implementation was beneficial to the laboratory, and none was in conflict with another approach. A synthesis of these approaches, built on a solid foundation of quality control planning, can help build a strong quality management system for the entire laboratory. Copyright © 2016 Elsevier Inc. All rights reserved.

  5. Health shocks and risk aversion.

    Science.gov (United States)

    Decker, Simon; Schmitz, Hendrik

    2016-12-01

    We empirically assess whether a health shock influences individual risk aversion. We use grip strength data to obtain an objective health shock indicator. In order to account for the non-random nature of our data regression-adjusted matching is employed. Risk preferences are traditionally assumed to be constant. However, we find that a health shock increases individual risk aversion. The finding is robust to a series of sensitivity analyses and persists for at least four years after the shock. Income changes do not seem to be the driving mechanism. Copyright © 2016 Elsevier B.V. All rights reserved.

  6. Evidence Report: Risk of Adverse Health Effects Due to Host-Microorganism Interactions

    Science.gov (United States)

    Ott, C. Mark; Oubre, Cherie; Wallace, Sarah; Mehta, Satish; Pierson, Duane

    2016-01-01

    While preventive measures limit the presence of many medically significant microorganisms during spaceflight missions, microbial infection of crewmembers cannot be completely prevented. Spaceflight experiments over the past 50 years have demonstrated a unique microbial response to spaceflight culture, although the mechanisms behind those responses and their operational relevance were unclear. In 2007, the operational importance of these microbial responses was emphasized as the results of an experiment aboard STS-115 demonstrated that the enteric pathogen Salmonella enterica serovar Typhimurium (S. Typhimurium) increased in virulence in a murine model of infection. The experiment was reproduced in 2008 aboard STS-123 confirming this finding. In response to these findings, the Institute of Medicine of the National Academies recommended that NASA investigate this risk and its potential impact on the health of the crew during spaceflight. NASA assigned this risk to the Human Research Program. To better understand this risk, evidence has been collected and reported from both spaceflight analog systems and actual spaceflight including Mir, Space Shuttle, and ISS missions. Although the performance of virulence studies during spaceflight are challenging and often impractical, additional information has been and continues to be collected to better understand the risk to crew health. Still, the uncertainty concerning the extent and severity of these alterations in host-microorganism interactions is very large and requires more investigation as the focus of human spaceflight shifts to longer-duration exploration class missions.

  7. Accounting for uncertainty and risk in assessments of impacts for offshore oil and gas leasing proposals

    International Nuclear Information System (INIS)

    Wildermann, R.; Beittel, R.

    1993-01-01

    The Minerals Management Service (MMS) of the US Department of the Interior prepares an environmental impact statement (EIS) for each proposal to lease a portion of the Outer Continental Shelf (OCS) for oil and gas exploration and development. The nature, magnitude, and timing of the activities that would ultimately result from leasing are subject to wide speculation, primarily because of uncertainties about the locations and amounts of petroleum hydrocarbons that exist on most potential leases. These uncertainties create challenges in preparing EIS's that meet National Environmental Policy Act requirements and provide information useful to decision-makers. This paper examines the constraints that uncertainty places on the detail and reliability of assessments of impacts from potential OCS development. It further describes how the MMS accounts for uncertainty in developing reasonable scenarios of future events that can be evaluated in the EIS. A process for incorporating the risk of accidental oil spills into assessments of expected impacts is also presented. Finally, the paper demonstrates through examination of case studies how a balance can be achieved between the need for an EIS to present impacts in sufficient detail to allow a meaningful comparison of alternatives and the tendency to push the analysis beyond credible limits

  8. HIT or miss: the application of health care information technology to managing uncertainty in clinical decision making.

    Science.gov (United States)

    Kazandjian, Vahé A; Lipitz-Snyderman, Allison

    2011-12-01

    To discuss the usefulness of health care information technology (HIT) in assisting care providers minimize uncertainty while simultaneously increasing efficiency of the care provided. An ongoing study of HIT, performance measurement (clinical and production efficiency) and their implications to the payment for care represents the design of this study. Since 2006, all Maryland hospitals have embarked on a multi-faceted study of performance measures and HIT adoption surveys, which will shape the health care payment model in Maryland, the last of the all-payor states, in 2011. This paper focuses on the HIT component of the Maryland care payment initiative. While the payment model is still under review and discussion, 'appropriateness' of care has been discussed as an important dimension of measurement. Within this dimension, the 'uncertainty' concept has been identified as associated with variation in care practices. Hence, the methods of this paper define how HIT can assist care providers in addressing the concept of uncertainty, and then provides findings from the first HIT survey in Maryland to infer the readiness of Maryland hospital in addressing uncertainty of care in part through the use of HIT. Maryland hospitals show noteworthy variation in their adoption and use of HIT. While computerized, electronic patient records are not commonly used among and across Maryland hospitals, many of the uses of HIT internally in each hospital could significantly assist in better communication about better practices to minimize uncertainty of care and enhance the efficiency of its production. © 2010 Blackwell Publishing Ltd.

  9. Unexpected uncertainty, volatility and decision-making

    Directory of Open Access Journals (Sweden)

    Amy Rachel Bland

    2012-06-01

    Full Text Available The study of uncertainty in decision making is receiving greater attention in the fields of cognitive and computational neuroscience. Several lines of evidence are beginning to elucidate different variants of uncertainty. Particularly, risk, ambiguity and expected and unexpected forms of uncertainty are well articulated in the literature. In this article we review both empirical and theoretical evidence arguing for the potential distinction between three forms of uncertainty; expected uncertainty, unexpected uncertainty and volatility. Particular attention will be devoted to exploring the distinction between unexpected uncertainty and volatility which has been less appreciated in the literature. This includes evidence from computational modelling, neuromodulation, neuroimaging and electrophysiological studies. We further address the possible differentiation of cognitive control mechanisms used to deal with these forms of uncertainty. Particularly we explore a role for conflict monitoring and the temporal integration of information into working memory. Finally, we explore whether the Dual Modes of Control theory provides a theoretical framework for understanding the distinction between unexpected uncertainty and volatility.

  10. A Risk-Free Protection Index Model for Portfolio Selection with Entropy Constraint under an Uncertainty Framework

    Directory of Open Access Journals (Sweden)

    Jianwei Gao

    2017-02-01

    Full Text Available This paper aims to develop a risk-free protection index model for portfolio selection based on the uncertain theory. First, the returns of risk assets are assumed as uncertain variables and subject to reputable experts’ evaluations. Second, under this assumption, combining with the risk-free interest rate we define a risk-free protection index (RFPI, which can measure the protection degree when the loss of risk assets happens. Third, note that the proportion entropy serves as a complementary means to reduce the risk by the preset diversification requirement. We put forward a risk-free protection index model with an entropy constraint under an uncertainty framework by applying the RFPI, Huang’s risk index model (RIM, and mean-variance-entropy model (MVEM. Furthermore, to solve our portfolio model, an algorithm is given to estimate the uncertain expected return and standard deviation of different risk assets by applying the Delphi method. Finally, an example is provided to show that the risk-free protection index model performs better than the traditional MVEM and RIM.

  11. Neural mechanisms mediating degrees of strategic uncertainty.

    Science.gov (United States)

    Nagel, Rosemarie; Brovelli, Andrea; Heinemann, Frank; Coricelli, Giorgio

    2018-01-01

    In social interactions, strategic uncertainty arises when the outcome of one's choice depends on the choices of others. An important question is whether strategic uncertainty can be resolved by assessing subjective probabilities to the counterparts' behavior, as if playing against nature, and thus transforming the strategic interaction into a risky (individual) situation. By means of functional magnetic resonance imaging with human participants we tested the hypothesis that choices under strategic uncertainty are supported by the neural circuits mediating choices under individual risk and deliberation in social settings (i.e. strategic thinking). Participants were confronted with risky lotteries and two types of coordination games requiring different degrees of strategic thinking of the kind 'I think that you think that I think etc.' We found that the brain network mediating risk during lotteries (anterior insula, dorsomedial prefrontal cortex and parietal cortex) is also engaged in the processing of strategic uncertainty in games. In social settings, activity in this network is modulated by the level of strategic thinking that is reflected in the activity of the dorsomedial and dorsolateral prefrontal cortex. These results suggest that strategic uncertainty is resolved by the interplay between the neural circuits mediating risk and higher order beliefs (i.e. beliefs about others' beliefs). © The Author(s) (2017). Published by Oxford University Press.

  12. Model Uncertainty via the Integration of Hormesis and LNT as the Default in Cancer Risk Assessment.

    Science.gov (United States)

    Calabrese, Edward J

    2015-01-01

    On June 23, 2015, the US Nuclear Regulatory Commission (NRC) issued a formal notice in the Federal Register that it would consider whether "it should amend its 'Standards for Protection Against Radiation' regulations from the linear non-threshold (LNT) model of radiation protection to the hormesis model." The present commentary supports this recommendation based on the (1) flawed and deceptive history of the adoption of LNT by the US National Academy of Sciences (NAS) in 1956; (2) the documented capacity of hormesis to make more accurate predictions of biological responses for diverse biological end points in the low-dose zone; (3) the occurrence of extensive hormetic data from the peer-reviewed biomedical literature that revealed hormetic responses are highly generalizable, being independent of biological model, end point measured, inducing agent, level of biological organization, and mechanism; and (4) the integration of hormesis and LNT models via a model uncertainty methodology that optimizes public health responses at 10(-4). Thus, both LNT and hormesis can be integratively used for risk assessment purposes, and this integration defines the so-called "regulatory sweet spot."

  13. Advanced methods for the risk, vulnerability and resilience assessment of safety-critical engineering components, systems and infrastructures, in the presence of uncertainties

    International Nuclear Information System (INIS)

    Pedroni, Nicolas

    2016-01-01

    Safety-critical industrial installations (e.g., nuclear plants) and infrastructures (e.g., power transmission networks) are complex systems composed by a multitude and variety of heterogeneous 'elements', which are highly interconnected and mutually dependent. In addition, such systems are affected by large uncertainties in the characterization of the failure and recovery behavior of their components, interconnections and interactions. Such characteristics raise concerns with respect to the system risk, vulnerability and resilience properties, which have to be accurately and precisely assessed for decision making purposes. In general, this entails the following main steps: (1) representation of the system to capture its main features; (2) construction of a mathematical model of the system; (3) simulation of the behavior of the system under various uncertain conditions to evaluate the relevant risk, vulnerability and resilience metrics by propagating the uncertainties through the mathematical model; (4) decision making to (optimally) determine the set of protective actions to effectively reduce (resp., increase) the system risk and vulnerability (resp., resilience). New methods to address these issues have been developed in this dissertation. Specifically, the research works have been carried out along two main axes: (1) the study of approaches for uncertainty modeling and quantification; (2) the development of advanced computational methods for the efficient system modeling, simulation and analysis in the presence of uncertainties. (author)

  14. Chemical Risk Assessment: Traditional vs Public Health ...

    Science.gov (United States)

    Preventing adverse health impacts from exposures to environmental chemicals is fundamental to protecting individual and public health. When done efficiently and properly, chemical risk assessment enables risk management actions that minimize the incidence and impacts of environmentally-induced diseases related to chemical exposure. However, traditional chemical risk assessment is faced with multiple challenges with respect to predicting and preventing disease in human populations, and epidemiological studies increasingly report observations of adverse health effects at exposure levels predicted from animal studies to be safe for humans. This discordance reinforces concerns about the adequacy of contemporary risk assessment practices (Birnbaum, Burke, & Jones, 2016) for protecting public health. It is becoming clear that to protect public health more effectively, future risk assessments will need to use the full range of available data, draw on innovative methods to integrate diverse data streams, and consider health endpoints that also reflect the range of subtle effects and morbidities observed in human populations. Given these factors, there is a need to reframe chemical risk assessment to be more clearly aligned with the public health goal of minimizing environmental exposures associated with disease. Preventing adverse health impacts from exposures to environmental chemicals is fundamental to protecting individual and public health. Chemical risk assessments

  15. Incorporating parametric uncertainty into population viability analysis models

    Science.gov (United States)

    McGowan, Conor P.; Runge, Michael C.; Larson, Michael A.

    2011-01-01

    Uncertainty in parameter estimates from sampling variation or expert judgment can introduce substantial uncertainty into ecological predictions based on those estimates. However, in standard population viability analyses, one of the most widely used tools for managing plant, fish and wildlife populations, parametric uncertainty is often ignored in or discarded from model projections. We present a method for explicitly incorporating this source of uncertainty into population models to fully account for risk in management and decision contexts. Our method involves a two-step simulation process where parametric uncertainty is incorporated into the replication loop of the model and temporal variance is incorporated into the loop for time steps in the model. Using the piping plover, a federally threatened shorebird in the USA and Canada, as an example, we compare abundance projections and extinction probabilities from simulations that exclude and include parametric uncertainty. Although final abundance was very low for all sets of simulations, estimated extinction risk was much greater for the simulation that incorporated parametric uncertainty in the replication loop. Decisions about species conservation (e.g., listing, delisting, and jeopardy) might differ greatly depending on the treatment of parametric uncertainty in population models.

  16. A commentary on model uncertainty

    International Nuclear Information System (INIS)

    Apostolakis, G.

    1994-01-01

    A framework is proposed for the identification of model and parameter uncertainties in risk assessment models. Two cases are distinguished; in the first case, a set of mutually exclusive and exhaustive hypotheses (models) can be formulated, while, in the second, only one reference model is available. The relevance of this formulation to decision making and the communication of uncertainties is discussed

  17. Impacts of “metals” on human health: uncertainties in using different Life Cycle Impact Assessment (LCIA) methodologies

    DEFF Research Database (Denmark)

    Pizzol, Massimo; Christensen, Per; Schmidt, Jannick Højrup

    This study looks into the uncertainties in determining the impact of “metals” emissions to human health, in Life Cycle Impact Assessment (LCIA). Metals are diverse substances, with different proprieties and characteristics, considered important in LCIA because of their toxicity to humans or ecosy......This study looks into the uncertainties in determining the impact of “metals” emissions to human health, in Life Cycle Impact Assessment (LCIA). Metals are diverse substances, with different proprieties and characteristics, considered important in LCIA because of their toxicity to humans...... be considered in an impact assessment focused on human health, and defined a list of 14 metals. We performed a contribution analysis in order to compare methods in relative terms; an approach successfully used in other studies. Various processes have been analyzed with 8 different LCIA methods in order...... to assess both how much each metal contributes to the total impact on human health, when only metal emissions are present, and how much metals in total contribute when also other toxic substances are included in the inventory of emissions. Differences between the methods are great and due...

  18. A multi-reservoir based water-hydroenergy management model for identifying the risk horizon of regional resources-energy policy under uncertainties

    International Nuclear Information System (INIS)

    Zeng, X.T.; Zhang, S.J.; Feng, J.; Huang, G.H.; Li, Y.P.; Zhang, P.; Chen, J.P.; Li, K.L.

    2017-01-01

    Highlights: • A multi-reservoir system can handle water/energy deficit, flood and sediment damage. • A MWH model is developed for planning a water allocation and energy generation issue. • A mixed fuzzy-stochastic risk analysis method (MFSR) can handle uncertainties in MWH. • A hybrid MWH model can plan human-recourse-energy with a robust and effective manner. • Results can support adjusting water-energy policy to satisfy increasing demands. - Abstract: In this study, a multi-reservoir based water-hydroenergy management (MWH) model is developed for planning water allocation and hydroenergy generation (WAHG) under uncertainties. A mixed fuzzy-stochastic risk analysis method (MFSR) is introduced to handle objective and subjective uncertainties in MWH model, which can couple fuzzy credibility programming and risk management within a general two-stage context, with aim to reflect the infeasibility risks between expected targets and random second-stage recourse costs. The developed MWH model (embedded by MFSR method) can be applied to a practical study of WAHG issue in Jing River Basin (China), which encounters conflicts between human activity and resource/energy crisis. The construction of water-energy nexus (WEN) is built to reflect integrity of economic development and resource/energy conservation, as well as confronting natural and artificial damages such as water deficit, electricity insufficient, floodwater, high sedimentation deposition contemporarily. Meanwhile, the obtained results with various credibility levels and target-violated risk levels can support generating a robust plan associated with risk control for identification of the optimized water-allocation and hydroenergy-generation alternatives, as well as flood controls. Moreover, results can be beneficial for policymakers to discern the optimal water/sediment release routes, reservoirs’ storage variations (impacted by sediment deposition), electricity supply schedules and system benefit

  19. A Semi-Infinite Interval-Stochastic Risk Management Model for River Water Pollution Control under Uncertainty

    Directory of Open Access Journals (Sweden)

    Jing Liu

    2017-05-01

    Full Text Available In this study, a semi-infinite interval-stochastic risk management (SIRM model is developed for river water pollution control, where various policy scenarios are explored in response to economic penalties due to randomness and functional intervals. SIRM can also control the variability of the recourse cost as well as capture the notion of risk in stochastic programming. Then, the SIRM model is applied to water pollution control of the Xiangxihe watershed. Tradeoffs between risks and benefits are evaluated, indicating any change in the targeted benefit and risk level would yield varied expected benefits. Results disclose that the uncertainty of system components and risk preference of decision makers have significant effects on the watershed's production generation pattern and pollutant control schemes as well as system benefit. Decision makers with risk-aversive attitude would accept a lower system benefit (with lower production level and pollutant discharge; a policy based on risk-neutral attitude would lead to a higher system benefit (with higher production level and pollutant discharge. The findings can facilitate the decision makers in identifying desired product generation plans in association with financial risk minimization and pollution mitigation.

  20. Environmental health risk assessment: Energy systems

    International Nuclear Information System (INIS)

    Krewski, D.; Somers, E.; Winthrop, S.O.

    1984-01-01

    Most industrialized nations have come to rely on a variety of systems for energy production, both of a conventional and non-conventional nature. In the paper, the spectrum of energy systems currently in use in Canada is outlined along with their potential health risks. Several examples of environmental health studies involving both outdoor and indoor air pollution related to energy production in Canada are reported. The limitations of current technologies for assessing health risks are discussed and possible approaches to managing energy related health risks are indicated. (author)

  1. Including uncertainty in hazard analysis through fuzzy measures

    International Nuclear Information System (INIS)

    Bott, T.F.; Eisenhawer, S.W.

    1997-12-01

    This paper presents a method for capturing the uncertainty expressed by an Hazard Analysis (HA) expert team when estimating the frequencies and consequences of accident sequences and provides a sound mathematical framework for propagating this uncertainty to the risk estimates for these accident sequences. The uncertainty is readily expressed as distributions that can visually aid the analyst in determining the extent and source of risk uncertainty in HA accident sequences. The results also can be expressed as single statistics of the distribution in a manner analogous to expressing a probabilistic distribution as a point-value statistic such as a mean or median. The study discussed here used data collected during the elicitation portion of an HA on a high-level waste transfer process to demonstrate the techniques for capturing uncertainty. These data came from observations of the uncertainty that HA team members expressed in assigning frequencies and consequences to accident sequences during an actual HA. This uncertainty was captured and manipulated using ideas from possibility theory. The result of this study is a practical method for displaying and assessing the uncertainty in the HA team estimates of the frequency and consequences for accident sequences. This uncertainty provides potentially valuable information about accident sequences that typically is lost in the HA process

  2. The Relation between Adolescent Self Assessment of Health and Risk Behaviours: Could a Global Measure of Health Provide Indications of Health Risk Exposures?

    Science.gov (United States)

    Nkansah-Amankra, Stephen; Walker, Ashley Dawn

    2012-01-01

    Objective: Self-rated health (SRH) has become a key organizing construct for assessing multiple dimensions of populations' physical and psychosocial health functioning. However, it is unclear how adolescents' subjective self assessment of health reflects health risk exposures, co-occurring health risks (problem behaviours) and other pre-existing…

  3. Regulatory risk assessments: Is there a need to reduce uncertainty and enhance robustness?

    Science.gov (United States)

    Snodin, D J

    2015-12-01

    A critical evaluation of several recent regulatory risk assessments has been undertaken. These relate to propyl paraben (as a food additive, cosmetic ingredient or pharmaceutical excipient), cobalt (in terms of a safety-based limit for pharmaceuticals) and the cancer Threshold of Toxicological Concern as applied to food contaminants and pharmaceutical impurities. In all cases, a number of concerns can be raised regarding the reliability of the current assessments, some examples being absence of data audits, use of single-dose and/or non-good laboratory practice studies to determine safety metrics, use of a biased data set and questionable methodology and lack of consistency with precedents and regulatory guidance. Drawing on these findings, a set of recommendations is provided to reduce uncertainty and improve the quality and robustness of future regulatory risk assessments. © The Author(s) 2015.

  4. Assessing uncertainty in extreme events: Applications to risk-based decision making in interdependent infrastructure sectors

    International Nuclear Information System (INIS)

    Barker, Kash; Haimes, Yacov Y.

    2009-01-01

    Risk-based decision making often relies upon expert probability assessments, particularly in the consequences of disruptive events and when such events are extreme or catastrophic in nature. Naturally, such expert-elicited probability distributions can be fraught with errors, as they describe events which occur very infrequently and for which only sparse data exist. This paper presents a quantitative framework, the extreme event uncertainty sensitivity impact method (EE-USIM), for measuring the sensitivity of extreme event consequences to uncertainties in the parameters of the underlying probability distribution. The EE-USIM is demonstrated with the Inoperability input-output model (IIM), a model with which to evaluate the propagation of inoperability throughout an interdependent set of economic and infrastructure sectors. The EE-USIM also makes use of a two-sided power distribution function generated by expert elicitation of extreme event consequences

  5. Occupational health and safety: Designing and building with MACBETH a value risk-matrix for evaluating health and safety risks

    Science.gov (United States)

    Lopes, D. F.; Oliveira, M. D.; Costa, C. A. Bana e.

    2015-05-01

    Risk matrices (RMs) are commonly used to evaluate health and safety risks. Nonetheless, they violate some theoretical principles that compromise their feasibility and use. This study describes how multiple criteria decision analysis methods have been used to improve the design and the deployment of RMs to evaluate health and safety risks at the Occupational Health and Safety Unit (OHSU) of the Regional Health Administration of Lisbon and Tagus Valley. ‘Value risk-matrices’ (VRMs) are built with the MACBETH approach in four modelling steps: a) structuring risk impacts, involving the construction of descriptors of impact that link risk events with health impacts and are informed by scientific evidence; b) generating a value measurement scale of risk impacts, by applying the MACBETH-Choquet procedure; c) building a system for eliciting subjective probabilities that makes use of a numerical probability scale that was constructed with MACBETH qualitative judgments on likelihood; d) and defining a classification colouring scheme for the VRM. A VRM built with OHSU members was implemented in a decision support system which will be used by OHSU members to evaluate health and safety risks and to identify risk mitigation actions.

  6. Comparative risk assessment for electricity generation

    International Nuclear Information System (INIS)

    Thoene, E.; Kallenbach, U.

    1988-01-01

    The following conclusions are drawn: There is no 'zero-risk option' in electricity generation. Risk comparison meets with considerable problems relating to available data and methods. Taking into account the existing uncertainties, technology ranking in terms of risks involved cannot be done, but the major risk elements of the various electricity generating systems can be clearly identified. The risks defined cannot be interpreted so as to lead to an abolishment of certain techniques due to risks involved, particularly if one sees the risks from electricity generation in relation to other health hazards. The use of coal for electricity generation clearly ranks top with regard to occupational risks and hazards to public health. (orig./HP) [de

  7. Bayesian Monte Carlo and Maximum Likelihood Approach for Uncertainty Estimation and Risk Management: Application to Lake Oxygen Recovery Model

    Science.gov (United States)

    Model uncertainty estimation and risk assessment is essential to environmental management and informed decision making on pollution mitigation strategies. In this study, we apply a probabilistic methodology, which combines Bayesian Monte Carlo simulation and Maximum Likelihood e...

  8. Age and gender differences in health risk perception.

    Science.gov (United States)

    Kim, YoungHo; Park, InKyoung; Kang, SooJin

    2018-03-01

    The current study investigated how adolescents perceive their own health risks and compare their own likelihood of health risks with that of others of the same age. Moreover, the study identified the differences in health risk perceptions between males and females. A total of 625 adolescents (314 males and 311 females) from the Nowon district, geographically located in northern Seoul, voluntarily participated. In order to measure health risk perceptions a Korean version of self-other risk judgments profile was used. The findings indicated that study participants, regardless of gender and age, tend to underestimate their vulnerability to majority of health risk events. Furthermore, there were significant gender and age differences in health risk perception and perception bias in all health risk domains. The present study suggests that further research is needed to identify realistic and unrealistic perception mechanism for a large number of people from different demographic and socioeconomic backgrounds. Copyright© by the National Institute of Public Health, Prague 2018.

  9. Analysis of health impact inputs to the US Department of Energy's risk information system

    Energy Technology Data Exchange (ETDEWEB)

    Droppo, J.G. Jr.; Buck, J.W.; Strenge, D.L.; Siegel, M.R.

    1990-08-01

    The US Department of Energy (DOE) is in the process of completing a survey of environmental problems, referred to as the Environmental Survey, at their facilities across the country. The DOE Risk Information System (RIS) is being used to prioritize these environmental problems identified in the Environmental Survey's findings. This report contains a discussion of site-specific public health risk parameters and the rationale for their inclusion in the RIS. These parameters are based on computed potential impacts obtained with the Multimedia Environmental Pollutant Assessment System (MEPAS). MEPAS is a computer-based methodology for evaluating the potential exposures resulting from multimedia environmental transport of hazardous materials. This report has three related objectives: document the role of MEPAS in the RIS framework, report the results of the analysis of alternative risk parameters that led to the current RIS risk parameters, and describe analysis of uncertainties in the risk-related parameters. 20 refs., 17 figs., 10 tabs.

  10. Uncertainty analysis in Monte Carlo criticality computations

    International Nuclear Information System (INIS)

    Qi Ao

    2011-01-01

    Highlights: ► Two types of uncertainty methods for k eff Monte Carlo computations are examined. ► Sampling method has the least restrictions on perturbation but computing resources. ► Analytical method is limited to small perturbation on material properties. ► Practicality relies on efficiency, multiparameter applicability and data availability. - Abstract: Uncertainty analysis is imperative for nuclear criticality risk assessments when using Monte Carlo neutron transport methods to predict the effective neutron multiplication factor (k eff ) for fissionable material systems. For the validation of Monte Carlo codes for criticality computations against benchmark experiments, code accuracy and precision are measured by both the computational bias and uncertainty in the bias. The uncertainty in the bias accounts for known or quantified experimental, computational and model uncertainties. For the application of Monte Carlo codes for criticality analysis of fissionable material systems, an administrative margin of subcriticality must be imposed to provide additional assurance of subcriticality for any unknown or unquantified uncertainties. Because of a substantial impact of the administrative margin of subcriticality on economics and safety of nuclear fuel cycle operations, recently increasing interests in reducing the administrative margin of subcriticality make the uncertainty analysis in criticality safety computations more risk-significant. This paper provides an overview of two most popular k eff uncertainty analysis methods for Monte Carlo criticality computations: (1) sampling-based methods, and (2) analytical methods. Examples are given to demonstrate their usage in the k eff uncertainty analysis due to uncertainties in both neutronic and non-neutronic parameters of fissionable material systems.

  11. Quantifying risk and accuracy in cancer risk assessment: the process and its role in risk management problem-solving.

    Science.gov (United States)

    Turturro, A; Hart, R W

    1987-01-01

    A better understanding of chemical-induced cancer has led to appreciation of similarities to problems addressed by risk management of radiation-induced toxicity. Techniques developed for cancer risk assessment of toxic substances can be generalized to toxic agents. A recent problem-solving approach for risk management of toxic substances developed for the U.S. Department of Health and Human Services, and the role of risk assessment and how uncertainty should be treated within the context of this approach, is discussed. Finally, two different methods, research into the assumptions underlying risk assessment and the modification of risk assessment/risk management documents, are used to illustrate how the technique can be applied.

  12. On using residual risk to assess the cost effectiveness and health protectiveness of remedy selection at superfund sites

    International Nuclear Information System (INIS)

    Katsumata, Peter T.; Kastenberg, William E.

    1998-01-01

    This article examines the importance of determining residual risk and its impact on remedy selection at Superfund Sites. Within this examination, risks are assessed using probabilistic models that incorporate the uncertainty and variability of the input parameters, and utilize parameter distributions based on current and applicable site-specific data. Monte Carlo methods are used to propagate these uncertainties and variabilities through the risk calculations resulting in a distribution for the estimate of both risk and residual risk. Such an approach permits an informed decision based on a broad information base which involves considering the entire uncertainty distribution of risk rather than a point estimate for each exposure scenario. Using the probabilistic risk estimates, with current and applicable site-specific data, alternative decisions regarding cleanup are obtained for two Superfund Sites

  13. Krypton-85 health risk assessment for a nuclear fuel reprocessing plant

    International Nuclear Information System (INIS)

    Mellinger, P.J.; Tanner, J.E.; Brackenbush, L.W.; Gilbert, E.S.

    1984-08-01

    A health risk assessment was conducted to investigate the impact of implementing regulations from the Environmental Protection Agency's Final Environmental Statement - 40 CFR 190 - Environmental Protection Requirements for Normal Operation of Activities in the Uranium Fuel Cycle. Potential risks involved in the routine release of 85 Kr from nuclear fuel reprocessing operations to the environment were compared to those resulting from the capture and storage of 85 Kr. The average occupationally exposed worker was estimated to receive about 400 to 600 mrem/y from 85 Kr recovery and immobilization activities. This dose is a factor of 20,000 to 30,000 higher than the estimated dose to the maximum offsite individual (0.02 mrem/y), and a factor of 130,000 to 200,000 higher than the dose received by the average member of the 50-mile population (0.003 mrem/y) from routine release of all 85 Kr. Given the uncertainties in the models used to generate lifetime risk numbers (0.02-0.027 radiation induced fatal cancers expected in the occupational workforce and 0.017 fatal cancers in the general population), the differences in total risks cannot be considered meaningful. There is certainly no reason to conclude that risks from 85 Kr routinely released to the environment are greater than those that would result from recovery, immobilization and storage of the noble gas. 22 references, 1 figure, 3 tables

  14. How Environmental Uncertainty Moderates the Effect of Relative Advantage and Perceived Credibility on the Adoption of Mobile Health Services by Chinese Organizations in the Big Data Era

    Directory of Open Access Journals (Sweden)

    Xing Chen

    2016-01-01

    Full Text Available Despite the importance of adoption of mobile health services by an organization on the diffusion of mobile technology in the big data era, it has received minimal attention in literature. This study investigates how relative advantage and perceived credibility affect an organization’s adoption of mobile health services, as well as how environmental uncertainty changes the relationship of relative advantage and perceived credibility with adoption. A research model that integrates relative advantage, perceived credibility, environmental uncertainty, and an organization’s intention to use mobile health service is developed. Quantitative data are collected from senior managers and information systems managers in 320 Chinese healthcare organizations. The empirical findings show that while relative advantage and perceived credibility both have positive effects on an organization’s intention to use mobile health services, relative advantage plays a more important role than perceived credibility. Moreover, environmental uncertainty positively moderates the effect of relative advantage on an organization’s adoption of mobile health services. Thus, mobile health services in environments characterized with high levels of uncertainty are more likely to be adopted because of relative advantage than in environments with low levels of uncertainty.

  15. How Environmental Uncertainty Moderates the Effect of Relative Advantage and Perceived Credibility on the Adoption of Mobile Health Services by Chinese Organizations in the Big Data Era.

    Science.gov (United States)

    Chen, Xing; Zhang, Xing

    2016-01-01

    Despite the importance of adoption of mobile health services by an organization on the diffusion of mobile technology in the big data era, it has received minimal attention in literature. This study investigates how relative advantage and perceived credibility affect an organization's adoption of mobile health services, as well as how environmental uncertainty changes the relationship of relative advantage and perceived credibility with adoption. A research model that integrates relative advantage, perceived credibility, environmental uncertainty, and an organization's intention to use mobile health service is developed. Quantitative data are collected from senior managers and information systems managers in 320 Chinese healthcare organizations. The empirical findings show that while relative advantage and perceived credibility both have positive effects on an organization's intention to use mobile health services, relative advantage plays a more important role than perceived credibility. Moreover, environmental uncertainty positively moderates the effect of relative advantage on an organization's adoption of mobile health services. Thus, mobile health services in environments characterized with high levels of uncertainty are more likely to be adopted because of relative advantage than in environments with low levels of uncertainty.

  16. Optimization under Uncertainty of Site-Specific Turbine Configurations: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Quick, Julian; Dykes, Katherine; Graf, Peter; Zahle, Frederik

    2016-11-01

    Uncertainty affects many aspects of wind energy plant performance and cost. In this study, we explore opportunities for site-specific turbine configuration optimization that accounts for uncertainty in the wind resource. As a demonstration, a simple empirical model for wind plant cost of energy is used in an optimization under uncertainty to examine how different risk appetites affect the optimal selection of a turbine configuration for sites of different wind resource profiles. If there is unusually high uncertainty in the site wind resource, the optimal turbine configuration diverges from the deterministic case and a generally more conservative design is obtained with increasing risk aversion on the part of the designer.

  17. Qualitative risk assessment for the 100-NR-2 Operable Unit. Revision 1

    International Nuclear Information System (INIS)

    1995-03-01

    This qualitative risk assessment provides information about the 100- NR-2 Groundwater Operable Unit of the Hanford reservation. Topics discussed in this report are: data evaluation; human health risk assessment overview; ecological evaluations; summary of uncertainty; results of both the ecological and human health evaluations; toxicity assessment; risk characterization; and a summary of contaminants of potential concern

  18. Risk assessments of regional climate change over Europe: generation of probabilistic ensemble and uncertainty assessment for EURO-CODEX

    Science.gov (United States)

    Yuan, J.; Kopp, R. E.

    2017-12-01

    Quantitative risk analysis of regional climate change is crucial for risk management and impact assessment of climate change. Two major challenges to assessing the risks of climate change are: CMIP5 model runs, which drive EURO-CODEX downscaling runs, do not cover the full range of uncertainty of future projections; Climate models may underestimate the probability of tail risks (i.e. extreme events). To overcome the difficulties, this study offers a viable avenue, where a set of probabilistic climate ensemble is generated using the Surrogate/Model Mixed Ensemble (SMME) method. The probabilistic ensembles for temperature and precipitation are used to assess the range of uncertainty covered by five bias-corrected simulations from the high-resolution (0.11º) EURO-CODEX database, which are selected by the PESETA (The Projection of Economic impacts of climate change in Sectors of the European Union based on bottom-up Analysis) III project. Results show that the distribution of SMME ensemble is notably wider than both distribution of raw ensemble of GCMs and the spread of the five EURO-CORDEX in RCP8.5. Tail risks are well presented by the SMME ensemble. Both SMME ensemble and EURO-CORDEX projections are aggregated to administrative level, and are integrated into impact functions of PESETA III to assess climate risks in Europe. To further evaluate the uncertainties introduced by the downscaling process, we compare the 5 runs from EURO-CORDEX with runs from the corresponding GCMs. Time series of regional mean, spatial patterns, and climate indices are examined for the future climate (2080-2099) deviating from the present climate (1981-2010). The downscaling processes do not appear to be trend-preserving, e.g. the increase in regional mean temperature from EURO-CORDEX is slower than that from the corresponding GCM. The spatial pattern comparison reveals that the differences between each pair of GCM and EURO-CORDEX are small in winter. In summer, the temperatures of EURO

  19. Work stress and health risk behavior.

    Science.gov (United States)

    Siegrist, Johannes; Rödel, Andreas

    2006-12-01

    This contribution discusses current knowledge of associations between psychosocial stress at work and health risk behavior, in particular cigarette smoking, alcohol consumption and overweight, by reviewing findings from major studies in the field published between 1989 and 2006. Psychosocial stress at work is measured by the demand-control model and the effort-reward imbalance model. Health risk behavior was analyzed in the broader context of a health-related Western lifestyle with socially and economically patterned practices of consumption. Overall, the review, based on 46 studies, only modestly supports the hypothesis of a consistent association between work stress and health risk behavior. The relatively strongest relationships have been found with regard to heavy alcohol consumption among men, overweight, and the co-manifestation of several risks. Suggestions for further research are given, and the need to reduce stressful experience in the framework of worksite health promotion programs is emphasized.

  20. Factors associated with confidence in decision making and satisfaction with risk communication among patients with atrial fibrillation.

    Science.gov (United States)

    Hedberg, Berith; Malm, Dan; Karlsson, Jan-Erik; Årestedt, Kristofer; Broström, Anders

    2018-06-01

    Atrial fibrillation is a prevalent cardiac arrhythmia. Effective communication of risks (e.g. stroke risk) and benefits of treatment (e.g. oral anticoagulants) is crucial for the process of shared decision making. The aim of this study was to explore factors associated with confidence in decision making and satisfaction with risk communication after a follow-up visit among patients who three months earlier had visited an emergency room for atrial fibrillation related symptoms. A cross-sectional design was used and 322 patients (34% women), mean age 66.1 years (SD 10.5 years) with atrial fibrillation were included in the south of Sweden. Clinical examinations were done post an atrial fibrillation episode. Self-rating scales for communication (Combined Outcome Measure for Risk Communication and Treatment Decision Making Effectiveness), uncertainty in illness (Mishel Uncertainty in Illness Scale-Community), mastery of daily life (Mastery Scale), depressive symptoms (Hospital Anxiety and Depression Scale) and vitality, physical health and mental health (36-item Short Form Health Survey) were used to collect data. Decreased vitality and mastery of daily life, as well as increased uncertainty in illness, were independently associated with lower confidence in decision making. Absence of hypertension and increased uncertainty in illness were independently associated with lower satisfaction with risk communication. Clinical atrial fibrillation variables or depressive symptoms were not associated with satisfaction with confidence in decision making or satisfaction with risk communication. The final models explained 29.1% and 29.5% of the variance in confidence in decision making and satisfaction with risk communication. Confidence in decision making is associated with decreased vitality and mastery of daily life, as well as increased uncertainty in illness, while absence of hypertension and increased uncertainty in illness are associated with risk communication satisfaction.