HARPS3 for a roboticized Isaac Newton Telescope

Science.gov (United States)

Thompson, Samantha J.; Queloz, Didier; Baraffe, Isabelle; Brake, Martyn; Dolgopolov, Andrey; Fisher, Martin; Fleury, Michel; Geelhoed, Joost; Hall, Richard; González Hernández, Jonay I.; ter Horst, Rik; Kragt, Jan; Navarro, Ramón; Naylor, Tim; Pepe, Francesco; Piskunov, Nikolai; Rebolo, Rafael; Sander, Louis; Ségransan, Damien; Seneta, Eugene; Sing, David; Snellen, Ignas; Snik, Frans; Spronck, Julien; Stempels, Eric; Sun, Xiaowei; Santana Tschudi, Samuel; Young, John

2016-08-01

We present a description of a new instrument development, HARPS3, planned to be installed on an upgraded and roboticized Isaac Newton Telescope by end-2018. HARPS3 will be a high resolution (R≃115,000) echelle spectrograph with a wavelength range from 380-690 nm. It is being built as part of the Terra Hunting Experiment - a future 10- year radial velocity measurement programme to discover Earth-like exoplanets. The instrument design is based on the successful HARPS spectrograph on the 3.6m ESO telescope and HARPS-N on the TNG telescope. The main changes to the design in HARPS3 will be: a customised fibre adapter at the Cassegrain focus providing a stabilised beam feed and on-sky fibre diameter ≍1:4 arcsec, the implementation of a new continuous ow cryostat to keep the CCD temperature very stable, detailed characterisation of the HARPS3 CCD to map the effective pixel positions and thus provide an improved accuracy wavelength solution, an optimised integrated polarimeter and the instrument integrated into a robotic operation. The robotic operation will optimise our programme which requires our target stars to be measured on a nightly basis. We present an overview of the entire project, including a description of our anticipated robotic operation.

TPC magnet cryogenic system

International Nuclear Information System (INIS)

Green, M.A.; Burns, W.A.; Taylor, J.D.; Van Slyke, H.W.

1980-03-01

The Time Projection Chamber (TPC) magnet at LBL and its compensation solenoids are adiabatically stable superconducting solenoid magnets. The cryogenic system developed for the TPC magnet is discussed. This system uses forced two-phase tubular cooling with the two cryogens in the system. The liquid helium and liquid nitrogen are delivered through the cooled load by forced tubular flow. The only reservoirs of liquid cryogen exist in the control dewar (for liquid helium) and the conditioner dewar (for liquid nitrogen). The operation o these systems during virtually all phases of system operation are described. Photographs and diagrams of various system components are shown, and cryogenic system data are presented in the following sections: (1) heat leaks into the TPC coil package and the compensation solenoids; (2) heat leaks to various components of the TPC magnet cryogenics system besides the magnets and control dewar; (3) the control dewar and its relationship to the rest of the system; (4) the conditioner system and its role in cooling down the TPC magnet; (5) gas-cooled electrical leads and charging losses; and (6) a summation of the liquid helium and liquid nitrogen requirements for the TPC superconducting magnet system

Closed depression topography and Harps soil, revisited

Science.gov (United States)

The Harps soil (Fine-loamy, mixed superactive, mesic Typic Calciaquoll) developed around wetland depressions. The purpose of this study is 1) to delineate surface deposition of carbonates representing Harps soil which results from outward and upward flow around closed depressions, and 2) to relate t...

The ALICE TPC Upgrad

Science.gov (United States)

Castro, Andrew; Alice-Usa Collaboration; Alice-Tpc Collaboration

2017-09-01

The Time Projection Chamber (TPC) currently used for ALICE (A Large Ion Collider Experiment at CERN) is a gaseous tracking detector used to study both proton-proton and heavy-ion collisions at the Large Hadron Collider (LHC) In order to accommodate the higher luminosit collisions planned for the LHC Run-3 starting in 2021, the ALICE-TPC will undergo a major upgrade during the next LHC shut down. The TPC is limited to a read out of 1000 Hz in minimum bias events due to the intrinsic dead time associated with back ion flow in the multi wire proportional chambers (MWPC) in the TPC. The TPC upgrade will handle the increase in event readout to 50 kHz for heavy ion minimum bias triggered events expected with the Run-3 luminosity by switching the MWPCs to a stack of four Gaseous Electron Multiplier (GEM) foils. The GEM layers will combine different hole pitches to reduce the dead time while maintaining the current spatial and energy resolution of the existing TPC. Undertaking the upgrade of the TPC represents a massive endeavor in terms of design, production, construction, quality assurance, and installation, thus the upgrade is coordinated over a number of institutes worldwide. The talk will go over the physics motivation for the upgrade, the ALICE-USA contribution to the construction of Inner Read Out Chambers IROCs, and QA from the first chambers built in the U.S

Characterization of a Spurious One-year Signal in HARPS Data

Science.gov (United States)

Dumusque, Xavier; Pepe, Francesco; Lovis, Christophe; Latham, David W.

2015-08-01

The HARPS spectrograph is showing an extreme stability, close to the m s-1 level, over more than 10 years of data. However, the radial velocities of some stars are contaminated by a spurious one-year signal with an amplitude that can be as high as a few m s-1. This signal is in opposition of phase with the revolution of Earth around the Sun and can be explained by the deformation of spectral lines crossing block stitchings of the CCD when the spectrum of an observed star is alternatively blueshifted and redshifted due to the motion of Earth around the Sun. This annual perturbation can be suppressed by either removing those affected spectral lines from the correlation mask used by the cross-correlation technique to derive precise radial velocities, or by simply fitting a yearly sinusoid to the radial velocity data. This is mandatory if we want to detect long-period low-amplitude signals in the HARPS radial velocities of quiet solar-type stars. Based on observations made with the HARPS instrument on the ESO 3.6 m telescope at the La Silla Observatory (Chile).

Searching for solar siblings among the HARPS data

Science.gov (United States)

Batista, S. F. A.; Adibekyan, V. Zh.; Sousa, S. G.; Santos, N. C.; Delgado Mena, E.; Hakobyan, A. A.

2014-04-01

The search for solar siblings has been particularly fruitful in the past few years. At present, there are four plausible candidates reported in the literature: HIP21158, HIP87382, HIP47399, and HIP92831. In this study we conduct a search for solar siblings among the HARPS high-resolution FGK dwarfs sample, which includes precise chemical abundances and kinematics for 1111 stars. Using a new approach based on chemical abundance trends with condensation temperature, kinematics, and ages we found one (additional) potential solar sibling candidate: HIP97507. Based on observations collected at the La Silla Paranal Observatory, ESO (Chile) with the HARPS spectrograph at the 3.6-m telescope (ESO runs ID 72.C-0488, 082.C-0212, and 085.C-0063).

The Kepler-10 planetary system revisited by HARPS-N

DEFF Research Database (Denmark)

Dumusque, Xavier; Bonomo, Aldo S.; Haywood, Raphaelle D.

2014-01-01

-N Collaboration decided to observe Kepler-10 intensively with the HARPS-N spectrograph on the Telescopio Nazionale Galileo on La Palma. In total, 148 high-quality radial-velocity measurements were obtained over two observing seasons. These new data allow us to improve the precision of the mass determination...

High-Gain Avalanche Rushing amorphous Photoconductor (HARP) detector

Energy Technology Data Exchange (ETDEWEB)

Tanioka, K. [NHK Science and Technical Research Laboratories, 1-10-11 Kinuta, Setagaya-ku, Tokyo 157-8510 (Japan)], E-mail: tanioka.k-jg@nhk.or.jp

2009-09-01

We have been studying a very sensitive image sensor since the early 1980s. In 1985, the author found for the first time that an experimental pickup tube with an amorphous selenium photoconductive target exhibits high sensitivity with excellent picture quality because of a continuous and stable avalanche multiplication phenomenon. We named the pickup tube with an amorphous photoconductive layer operating in the avalanche-mode 'HARP': High-gain Avalanche Rushing amorphous Photoconductor. A color camera equipped with the HARP pickup tubes has a maximum sensitivity of 11 lx at F8. This means that the HARP camera is about 100 times as sensitive as that of CCD camera for broadcasting. This ultrahigh-sensitivity HARP pickup tube is a powerful tool for reporting breaking news at night and other low-light conditions, the production of scientific programs, and numerous other applications, including medical diagnoses, biotech research, and nighttime surveillance. In addition, since the HARP target can convert X-rays into electrons directly, it should be possible to exploit this capability to produce X-ray imaging devices with unparalleled levels of resolution and sensitivity.

ALICE installs its TPC

CERN Multimedia

2007-01-01

The ALICE time projection chamber has been transported to the experimental cavern. The handling of this extremely fragile detector was a long and delicate process. The lorry transporting the TPC took one hour to travel from the assembly hall to the access shaft...200 metres away.The TPC was lowered into the ALICE experimental cavern with extreme care. The gap between the structure and the shaft wall was only 10 centimetres! For ALICE the year started with a flurry of activity...but at a snail's pace. On 8 January, the day CERN reopened after the end-of-year break, teams from ALICE and the TS Department began the transportation of the experiment's time projection chamber (TPC), the largest ever built. This 5-metre long and 5-m diameter cylinder was transported from the clean room where it had been assembled to the experimental cavern. The 300-metre journey took no less than four days! Since the TPC is an extremely fragile object, the utmost precautions were exercised in its transportation. The TPC, which is d...

Methylmercury poisoning in the harp seal (Pagophilus groenlandicus)

Energy Technology Data Exchange (ETDEWEB)

Ronald, K [Univ. of Guelph, Ont.; Tessaro, S V; Uthe, J F; Freeman, H C; Frank, R

1977-07-01

Hematological and blood chemistry values were examined in harp seals (Pagophilus groenlandicus) exposed to daily oral dosages of methylmercuric chloride (MMC). Two seals, exposed to 0.25 mg MMC/kg body weight/day for 60 and 90 days, respectively, died not show abnormal blood values. Two other seals exposed to 25.0 mg MMC/kg body weight/day died on day 20 and 26 of exposure. Blood parameters indicated toxic hepatitis, uremia and renal failure. Total mercury and methylmercury values in the tissues of the experimental animals indicated that harp seals can tolerate high levels of mercury in the brain and that the observed renal and hepatic dysfunction were related to the high accumulation of mercury in these tissues. Tests of renal function are useful in cases of severe methylmercury poisoning.

Music thanatology: prescriptive harp music as palliative care for the dying patient.

Science.gov (United States)

Freeman, Lindsay; Caserta, Michael; Lund, Dale; Rossa, Shirley; Dowdy, Ann; Partenheimer, Andrea

2006-01-01

Music thanatology represents an emerging area in which the raw materials of music, usually harp and/or voice, assist and comfort the dying patient. During prescriptive "music vigils, " the clinician-musician carefully observes physiological changes, cues, and breathing patterns, thereby synchronizing the music to reflect or support the patient's physiology and overall condition. Using data collected from 65 patients, this study was designed to assess the effectiveness of prescriptive harp music on selected palliative care outcomes using a sample of de-identified data forms from past music vigils. Patients were administered a 25- to 95-minute intervention of prescriptive harp music. Data collected included vital signs and observational indicators before (Ti) and after (T2) the vigil. Patients were more likely to experience decreased levels of agitation and wakefulness while also breathing more slowly and deeply with less effort at the conclusion of the music vigil. Results from this study suggest that a prescriptive vigil conducted by a trained music thanatologist could provide an effective form of palliative care for dying patients.

The effects of harp music in vascular and thoracic surgical patients.

Science.gov (United States)

Aragon, Daleen; Farris, Carla; Byers, Jacqueline F

2002-01-01

Music has been used in the acute clinical care setting as an adjunct to current treatment modalities. Previous studies have indicated that some types of music may benefit patients by reducing pain and anxiety, and may have an effect on physiological measures. To evaluate the scientific foundation for the implementation of a complementary therapy, harp playing. The research questions for this pilot study were: Does live harp playing have an effect on patient perception of anxiety, pain, and satisfaction? Does live harp playing produce statistically and clinically significant differences in physiological measures of heart rate, systolic and diastolic blood pressure, respiratory rate, and oxygen saturation? A prospective, quasiexperimental, repeated measures design was used with a convenience sampling. Orlando Regional Medical Center, Orlando Fla. Subjects wer eligible for the study if they were postoperative and admitted to a hard-wired-bedside-monitored room of the Vascular Thoracic Unit within the 3 days of the study period. A singl e20-minute live harp playing session. Visual analog scales (VAS) were used to measure patient anxiety and pain. Patient satisfaction was measured with a 4-item questionnaire. Physiological measures (heart rate, systolic and diastolic blood pressure, respiratory rate, and oxygen saturation) were recorded from the bedside monitor. Visual analog scales (VAS) were completed just before harp playing, 20 minutes after harp playing was started, and 10 minutes after completion. Patient satisfaction with the experience was measured with a 4-item questionnaire. Physiological measures (heart rate, systolic and diastolic blood pressure, respiratory rate, and oxygen saturation) were recorded from the bedside monitor at baseline (5 minutes before study setup), at zero, 5, 10, 15, and 20 minutes after harp playing began, and at 5 and 10 minutes after harp playing stopped. Seventeen patients were used in this study, with a retrospective power of .91

HARP preferentially co-purifies with RPA bound to DNA-PK and blocks RPA phosphorylation.

Science.gov (United States)

Quan, Jinhua; Yusufzai, Timur

2014-05-01

The HepA-related protein (HARP/SMARCAL1) is an ATP-dependent annealing helicase that is capable of rewinding DNA structures that are stably unwound due to binding of the single-stranded DNA (ssDNA)-binding protein Replication Protein A (RPA). HARP has been implicated in maintaining genome integrity through its role in DNA replication and repair, two processes that generate RPA-coated ssDNA. In addition, mutations in HARP cause a rare disease known as Schimke immuno-osseous dysplasia. In this study, we purified HARP containing complexes with the goal of identifying the predominant factors that stably associate with HARP. We found that HARP preferentially interacts with RPA molecules that are bound to the DNA-dependent protein kinase (DNA-PK). We also found that RPA is phosphorylated by DNA-PK in vitro, while the RPA-HARP complexes are not. Our results suggest that, in addition to its annealing helicase activity, which eliminates the natural binding substrate for RPA, HARP blocks the phosphorylation of RPA by DNA-PK.

How to Advance TPC Benchmarks with Dependability Aspects

Science.gov (United States)

Almeida, Raquel; Poess, Meikel; Nambiar, Raghunath; Patil, Indira; Vieira, Marco

Transactional systems are the core of the information systems of most organizations. Although there is general acknowledgement that failures in these systems often entail significant impact both on the proceeds and reputation of companies, the benchmarks developed and managed by the Transaction Processing Performance Council (TPC) still maintain their focus on reporting bare performance. Each TPC benchmark has to pass a list of dependability-related tests (to verify ACID properties), but not all benchmarks require measuring their performances. While TPC-E measures the recovery time of some system failures, TPC-H and TPC-C only require functional correctness of such recovery. Consequently, systems used in TPC benchmarks are tuned mostly for performance. In this paper we argue that nowadays systems should be tuned for a more comprehensive suite of dependability tests, and that a dependability metric should be part of TPC benchmark publications. The paper discusses WHY and HOW this can be achieved. Two approaches are introduced and discussed: augmenting each TPC benchmark in a customized way, by extending each specification individually; and pursuing a more unified approach, defining a generic specification that could be adjoined to any TPC benchmark.

HiRel: Hybrid Automated Reliability Predictor (HARP) integrated reliability tool system, (version 7.0). Volume 1: HARP introduction and user's guide

Science.gov (United States)

Bavuso, Salvatore J.; Rothmann, Elizabeth; Dugan, Joanne Bechta; Trivedi, Kishor S.; Mittal, Nitin; Boyd, Mark A.; Geist, Robert M.; Smotherman, Mark D.

1994-01-01

The Hybrid Automated Reliability Predictor (HARP) integrated Reliability (HiRel) tool system for reliability/availability prediction offers a toolbox of integrated reliability/availability programs that can be used to customize the user's application in a workstation or nonworkstation environment. HiRel consists of interactive graphical input/output programs and four reliability/availability modeling engines that provide analytical and simulative solutions to a wide host of reliable fault-tolerant system architectures and is also applicable to electronic systems in general. The tool system was designed to be compatible with most computing platforms and operating systems, and some programs have been beta tested, within the aerospace community for over 8 years. Volume 1 provides an introduction to the HARP program. Comprehensive information on HARP mathematical models can be found in the references.

The EyeHarp: A Gaze-Controlled Digital Musical Instrument.

Science.gov (United States)

Vamvakousis, Zacharias; Ramirez, Rafael

2016-01-01

We present and evaluate the EyeHarp, a new gaze-controlled Digital Musical Instrument, which aims to enable people with severe motor disabilities to learn, perform, and compose music using only their gaze as control mechanism. It consists of (1) a step-sequencer layer, which serves for constructing chords/arpeggios, and (2) a melody layer, for playing melodies and changing the chords/arpeggios. We have conducted a pilot evaluation of the EyeHarp involving 39 participants with no disabilities from both a performer and an audience perspective. In the first case, eight people with normal vision and no motor disability participated in a music-playing session in which both quantitative and qualitative data were collected. In the second case 31 people qualitatively evaluated the EyeHarp in a concert setting consisting of two parts: a solo performance part, and an ensemble (EyeHarp, two guitars, and flute) performance part. The obtained results indicate that, similarly to traditional music instruments, the proposed digital musical instrument has a steep learning curve, and allows to produce expressive performances both from the performer and audience perspective.

The RoPES project with HARPS and HARPS-N. I. A system of super-Earths orbiting the moderately active K-dwarf HD 176986

Science.gov (United States)

Suárez Mascareño, A.; González Hernández, J. I.; Rebolo, R.; Velasco, S.; Toledo-Padrón, B.; Udry, S.; Motalebi, F.; Ségrasan, D.; Wyttenbach, A.; Mayor, M.; Pepe, F.; Lovis, C.; Santos, N. C.; Figueira, P.; Esposito, M.

2018-04-01

We report the discovery of a system of two super-Earths orbiting the moderately active K-dwarf HD 176986. This work is part of the RoPES RV program of G- and K-type stars, which combines radial velocities (RVs) from the HARPS and HARPS-N spectrographs to search for short-period terrestrial planets. HD 176986 b and c are super-Earth planets with masses of 5.74 and 9.18 M⊕, orbital periods of 6.49 and 16.82 days, and distances of 0.063 and 0.119 AU in orbits that are consistent with circular. The host star is a K2.5 dwarf, and despite its modest level of chromospheric activity (log10 (RHK' = -4.90 ± 0.04), it shows a complex activity pattern. Along with the discovery of the planets, we study the magnetic cycle and rotation of the star. HD 176986 proves to be suitable for testing the available RV analysis technique and further our understanding of stellar activity. Full Table A.1 is only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/612/A41Based on observations made with the Italian Telescopio Nazionale Galileo (TNG), operated on the island of La Palma by the INAF - Fundación Galileo Galilei at the Roche de Los Muchachos Observatory of the Instituto de Astrofísica de Canarias (IAC); observations made with the HARPS instrument on the ESO 3.6-m telescope at La Silla Observatory (Chile).

CAMAC interface for TPC data-acquisition electronics

International Nuclear Information System (INIS)

Sidman, S.; Olson, S.; Jared, R.

1983-06-01

The Time Projection Chamber (TPC) is a detector used for high-energy physics research at the Stanford PEP Accelerator. TPC requires about 17,000 channels of data acquisition, which samples on command the input to each channel at a 10 MHz rate. This high data rate is made possible by means of Charge Coupled Devices (CCDs), intelligent digitizers, and a sophisticated trigger system. The TPC-CAMAC interface described here was developed to allow experiments of smaller scale than the complete TPC to use the standard data acquisition portion of the TPC electronics, namely the amplifier, CCD and digitizer bins. These three bins, when properly interconnected and controlled by the interface control bin, form a transient digitizer with a depth of 455 samples and a maximum width of 256 channels per bin set

Free electron lifetime achievements in Liquid Argon Imaging TPC

CERN Document Server

Baibussinov, B; Calligarich, E; Centro, S; Cieslik, K; Farnese, C; Fava, A; Gibin, D; Guglielmi, A; Meng, G; Pietropaolo, F; Rubbia, C; Varanini, F; Ventura, S

2010-01-01

A key feature for the success of the Liquid Argon TPC technology is the industrial purification against electro-negative impurities, especially Oxygen and Nitrogen remnants, which have to be initially and continuously kept at an exceptional purity. New purification techniques have been applied to a 120 litres LAr-TPC test facility in the INFN-LNL laboratory. Through-going muon tracks have been used to monitor the LAr purity. The short path length used (30 cm) is compensated by the high accuracy in the observation of the specific ionization of cosmic rays muons at sea level. A free electron lifetime of (21.4+7.3-4.3) ms, namely > 15.8 ms at 90 % C.L. has been observed under stable conditions over several weeks, corresponding to about 15 ppt (part per trillion) of Oxygen equivalent. At 500 V/cm, where the electron speed is approximately of 1.5 mm/us, the free electron lifetime >15 ms corresponds to an attenuation <15 % for a drift path of 5 m, opening the way to reliable operation of LAr TPC for exceptionall...

Feeding habits of harp and hooded seals in Greenland waters

Directory of Open Access Journals (Sweden)

Finn O Kapel

2000-05-01

Full Text Available Results of stomach contents analyses of harp and hooded seals collected in West Greenland waters in the period 1986-1993 are reviewed, and compared with published data and circumstantial information from local hunters.  The diet of harp seals in this region is variable but consists mainly of pelagic crustaceans (Thysanoessa spp. and Parathemisto libellula and small fish species like capelin (Mallotus villosus, sandeel (Ammodytes spp., polar cod (Boreogadus saida and Arctic cod (Arctogadus glacialis. Species of importance for commercial fisheries in Greenland, such as Northern prawn (Pandalus borealis, Atlantic cod (Gadus morhua, and Greenland halibut (Reinhardtius hippoglossoides play a minor role in the diet of harp seals in this area. Variation in the diet of hooded seals is less well documented, but in addition to the species also taken by harp seals, larger demersal fishes like Greenland halibut, redfish (Sebastes spp., cod, and wolffish (Anarhichas minor are apparently important prey items.

Performance and applications of a μ-TPC

International Nuclear Information System (INIS)

Miuchi, Kentaro; Kubo, Hidetoshi; Nagayoshi, Tsutomu; Okada, Yoko; Orito, Reiko; Takada, Atsushi; Takeda, Atsushi; Tanimori, Toru; Ueno, Masaru; Bouianov, Oleg; Bouianov, Marina

2004-01-01

A μ-TPC, a time projection chamber (TPC) which can detect three-dimensional fine tracks of charged particles, was developed and its performance was measured. We developed a μ-TPC with a detection volume of 10x10x10cm3 based on a novel two-dimensional imaging gaseous detector, or the μ-PIC. Fine tracks of charged particles with large energy depositions (protons and electrons) were detected with the μ-TPC. With a pressurized gas, tracks of the minimum ionizing particles were detected. We showed the principle of the application for the time-resolved neutron imaging detector

The HARP resistive plate chambers: Characteristics and physics performance

International Nuclear Information System (INIS)

Ammosov, V.; Boyko, I.; Chelkov, G.; Dedovitch, D.; Dumps, R.; Dydak, F.; Elagin, A.; Gapienko, V.; Gostkin, M.; Guskov, A.; Kroumchtein, Z.; Koreshev, V.; Linssen, L.; Nefedov, Yu.; Nikolaev, K.; Semak, A.; Sviridov, Yu.; Usenko, E.; Wotschack, J.; Zaets, V.; Zhemchugov, A.

2007-01-01

The HARP Resistive Plate Chamber (RPC) system was designed for time-of-flight measurement in the large-angle acceptance region of the HARP spectrometer. It comprised 46 four-gap glass RPCs covering an area of ∼8m 2 . The design of the RPCs, their operation, intrinsic properties, and system performance are described. The intrinsic time resolution of the RPCs is better than 130ps leading to a system time resolution of ∼175ps

Compression of TPC data in the ALICE experiment

International Nuclear Information System (INIS)

Nicolaucig, A.; Mattavelli, M.; Carrato, S.

2002-01-01

In this paper two algorithms for the compression of the data generated by the Time Projection Chamber (TPC) detector of the ALICE experiment at CERN are described. The first algorithm is based on a lossless source code modeling technique, i.e. the original TPC signal information can be reconstructed without errors at the decompression stage. The source model exploits the temporal correlation that is present in the TPC data to reduce the entropy of the source. The second algorithm is based on a source model which is lossy if samples of the TPC signal are considered one by one. Conversely, the source model is lossless or quasi-lossless if some physical quantities that are of main interest for the experiment are considered. These quantities are the area and the location of the center of mass of each TPC signal pulse. Obviously entropy coding is applied to the set of events defined by the two source models to reduce the bit rate to the corresponding source entropy. Using TPC simulated data according to the expected ALICE TPC performance, the lossless and the lossy compression algorithms achieve a data reduction, respectively, to 49.2% and in the range of 34.2% down to 23.7% of the original data rate. The number of operations per input symbol required to implement the compression stage for both algorithms is relatively low, so that a real-time implementation embedded in the TPC data acquisition chain using low-cost integrated electronics is a realistic option to effectively reduce the data storing cost of ALICE experiment

Cryogenic testing of the TPC superconducting solenoid

International Nuclear Information System (INIS)

Green, M.A.; Smits, R.G.; Taylor, J.D.

1983-06-01

This report describes the results of a series of tests on the TPC superconducting magnet cryogenic system which occurred during the winter and spring of 1983. The tests occurred at interaction region 2 of the PEP colliding beam facility at the Stanford Linear Accelerator Center (SLAC). The TPC Magnet Cryogenic System which was tested includes the following major components: a remote helium compressor with a full flow liquid nitrogen purification station, 400 meters of high pressure supply and low pressure return lines; and locally a CTi Model 2800 refrigerator with two Sulzer gas bearing turbines, the TPC magnet control dewar, 70 meters of transfer lines, and the TPC thin superconducting solenoid magnet. In addition, there is a conditioner (liquid nitrogen heat exchangers and gas heaters) system for cooldown and warmup of the magnet. This report describes the local cryogenic system and describes the various steps in the cooldown and operation of the TPC magnet. The tests were successful in that they showed that the TPC magnet could be cooled down in 24 hours and the magnet could be operated on the refrigerator or a helium pump with adequate cooling margin. The tests identified problems with the cryogenic system and the 2800 refrigerator. Procedures for successful operation and quenching of the superconducting magnet were developed. 19 references

Strange particle measurements from the EOS TPC

International Nuclear Information System (INIS)

Justice, M.

1995-02-01

A high statistics sample of Λ's produced in 2 GeV/nucleon 5 8Ni + nat Cu collisions has been obtained with the EOS Time Projection Chamber at the Bevalac. The coverage of the EOS TPC is essentially 100% for y > y cm and extends down to P T = 0 where interesting effects such as collective radial expansion may be important. In addition, the detection of a majority of the charged particles in the TPC, along with the presence of directed flow for protons and heavier fragments at this beam energy, allows for the correlation of A production with respect to the event reaction plane. Our preliminary analysis indicates the first observation of a sidewards flow signature for A's. Comparisons with the cascade code ARC are made

Optimized iterative decoding method for TPC coded CPM

Science.gov (United States)

Ma, Yanmin; Lai, Penghui; Wang, Shilian; Xie, Shunqin; Zhang, Wei

2018-05-01

Turbo Product Code (TPC) coded Continuous Phase Modulation (CPM) system (TPC-CPM) has been widely used in aeronautical telemetry and satellite communication. This paper mainly investigates the improvement and optimization on the TPC-CPM system. We first add the interleaver and deinterleaver to the TPC-CPM system, and then establish an iterative system to iteratively decode. However, the improved system has a poor convergence ability. To overcome this issue, we use the Extrinsic Information Transfer (EXIT) analysis to find the optimal factors for the system. The experiments show our method is efficient to improve the convergence performance.

The ALICE TPC

CERN Document Server

Garabatos, C

2004-01-01

We describe the ALICE TPC, with emphasis on the design features which are driven by the physics requirements of the detector. In particular, the gas choice and composition, Ne-CO/sub 2/ Ý90-10¿, as well as the unprecedentedly high gain for a TPC (2*10/sup 40/), are direct consequences of the expected performance in the high- multiplicity environment of heavy-ion collisions at the LHC. The characteristics of this mixture are discussed and a viable way of improving the stability of detectors working under these conditions, namely the addition of nitrogen into the mixture, is presented. This results in a more effective Penning transfer of neon excited states onto ionisation of the quencher at no penalty for the charge transport and amplification properties.

Particle Identification Studies with an ALICE Test TPC

CERN Document Server

Christiansen, P

2007-01-01

Using a test TPC, consisting of the ALICE TPC field cage prototype in combination with the final ALICE TPC readout and electronics, the energy loss distribution and resolution were measured for identified protons. The measurements were compared to theoretical calculations and good quantitative agreement was found when detector effects were taken into account. The implications for particle identification are discussed.

A laser calibration system for the STAR TPC

CERN Document Server

Lebedev, A

2002-01-01

A Time Projection Chamber (TPC) is the primary tracking detector for the STAR experiment at RHIC. A laser calibration system was built to calibrate and monitor the TPC tracking performance. The laser system uses a novel design which produces approx 500 thin, ionizing beams distributed throughout the tracking volume. This new approach is significantly simpler than the traditional ones, and provides complete TPC coverage at a reduced cost. The laser system was used during the RHIC 2000 summer run to measure drift velocities with about 0.02% accuracy and to monitor the TPC performance. Calibration runs were made with and without a magnetic field to check B field map corrections.

VizieR Online Data Catalog: HD20794 HARPS radial velocities (Feng+, 2017)

Science.gov (United States)

Feng, F.; Tuomi, M.; Jones, H. R. A.

2017-05-01

HARPS radial velocities, activity indices and differential radial velocities for HD 20794. The HARPS spectra are available in the European Southern Observatory archive, and are processed using the TERRA algorithm (Anglada-Escude and Butler, 2012, Cat. J/ApJS/200/15). (1 data file).

A micromegas-based TPC for the International Linear Collider

International Nuclear Information System (INIS)

Bhattacharya, Deb Sankar; Mukhopadhyay, Supratik; Majumdar, Nayana; Sarkar, Sandip; Bhattacharya, Sudeb; Bhattacharya, Purba; Colas, Paul; Attié, David; Ganjour, Serguei; Bhattacharya, Aparajita

2016-01-01

One of the two detector concepts for the ILC is the International Large Detector (ILD). The central tracking at the ILD is foreseen to be accomplished by a TPC (the ILD-TPC). A TPC has the benefits of truly continuous 3-D tracking and robust pattern recognition. In the baseline design, the length and the diameter of the ILD-TPC are 4.6 m and 3.6 m respectively. It will work in a 3.5 T magnetic field. Micromegas is a promising candidate for the ILD-TPC. Like any other MPGD, track reconstruction at the LPTPC with Micromegas has challenges. The electric field inhomogeneity near the gap between the modules results in track distortion and affects the performance of the TPC. The causes and effects of this distortion have been thoroughly studied by numerical methods. The results match closely with experiment. Possible hardware modifications to mitigate distortion effect have been explored in simulation

HiRel: Hybrid Automated Reliability Predictor (HARP) integrated reliability tool system, (version 7.0). Volume 4: HARP Output (HARPO) graphics display user's guide

Science.gov (United States)

Sproles, Darrell W.; Bavuso, Salvatore J.

1994-01-01

The Hybrid Automated Reliability Predictor (HARP) integrated Reliability (HiRel) tool system for reliability/availability prediction offers a toolbox of integrated reliability/availability programs that can be used to customize the user's application in a workstation or nonworkstation environment. HiRel consists of interactive graphical input/output programs and four reliability/availability modeling engines that provide analytical and simulative solutions to a wide host of highly reliable fault-tolerant system architectures and is also applicable to electronic systems in general. The tool system was designed at the outset to be compatible with most computing platforms and operating systems and some programs have been beta tested within the aerospace community for over 8 years. This document is a user's guide for the HiRel graphical postprocessor program HARPO (HARP Output). HARPO reads ASCII files generated by HARP. It provides an interactive plotting capability that can be used to display alternate model data for trade-off analyses. File data can also be imported to other commercial software programs.

Noise Characterization and Filtering in the MicroBooNE Liquid Argon TPC

Energy Technology Data Exchange (ETDEWEB)

Acciarri, R.; et al.

2017-05-20

The low-noise operation of readout electronics in a liquid argon time projection chamber (LArTPC) is critical to properly extract the distribution of ionization charge deposited on the wire planes of the TPC, especially for the induction planes. This paper describes the characteristics and mitigation of the observed noise in the MicroBooNE detector. The MicroBooNE's single-phase LArTPC comprises two induction planes and one collection sense wire plane with a total of 8256 wires. Current induced on each TPC wire is amplified and shaped by custom low-power, low-noise ASICs immersed in the liquid argon. The digitization of the signal waveform occurs outside the cryostat. Using data from the first year of MicroBooNE operations, several excess noise sources in the TPC were identified and mitigated. The residual equivalent noise charge (ENC) after noise filtering varies with wire length and is found to be below 400 electrons for the longest wires (4.7 m). The response is consistent with the cold electronics design expectations and is found to be stable with time and uniform over the functioning channels. This noise level is significantly lower than previous experiments utilizing warm front-end electronics.

CHARACTERIZATION OF A SPURIOUS ONE-YEAR SIGNAL IN HARPS DATA

Energy Technology Data Exchange (ETDEWEB)

Dumusque, Xavier; Latham, David W. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Pepe, Francesco; Lovis, Christophe, E-mail: xdumusque@cfa.harvard.edu [Observatoire Astronomique de l’Université de Genève, 51 Chemin des Mailettes, 1290 Sauverny (Switzerland)

2015-08-01

The HARPS spectrograph is showing an extreme stability, close to the m s{sup −1} level, over more than 10 years of data. However, the radial velocities of some stars are contaminated by a spurious one-year signal with an amplitude that can be as high as a few m s{sup −1}. This signal is in opposition of phase with the revolution of Earth around the Sun and can be explained by the deformation of spectral lines crossing block stitchings of the CCD when the spectrum of an observed star is alternatively blueshifted and redshifted due to the motion of Earth around the Sun. This annual perturbation can be suppressed by either removing those affected spectral lines from the correlation mask used by the cross-correlation technique to derive precise radial velocities, or by simply fitting a yearly sinusoid to the radial velocity data. This is mandatory if we want to detect long-period low-amplitude signals in the HARPS radial velocities of quiet solar-type stars.

Closed depression topography Harps soil, revisited

Science.gov (United States)

Accumulation of carbonates around depressions indicates past or present water and solute flow paths out and up from the depressions. The purpose of this study was to determine the pattern of surface carbonates in relation to landscape parameters, depressions, and original Harps map units. Surface ca...

ALICE Time Projection Chamber (TPC) Readout Sector in Lab

CERN Multimedia

2003-01-01

The Time Projection Chamber (TPC) is the main particle tracking detector in ALICE. Charged particles crossing the gas of the TPC knock electrons out of their atoms, which drift in the eletric field. By measuring the arrival of electrons at the end of the chamber, at segments such as the one shown here, the TPC will reconstruct the paths of the original charged particles.

Experimental observation of an extremely high electron lifetime with the ICARUS-T600 LAr-TPC

CERN Document Server

Antonello, M; Benetti, P; Boffelli, F; Bubak, A; Calligarich, E; Centro, S; Cesana, A; Cieslik, K; Cline, D B; Cocco, A G; Dabrowska, A; Dermenev, A; Dolfini, R; Falcone, A; Farnese, C; Fava, A; Ferrari, A; Fiorillo, G; Gibin, D; Gninenko, S; Guglielmi, A; Haranczyk, M; Holeczek, J; Kirsanov, M; Kisiel, J; Kochanek, I; Lagoda, J; Mania, S; Menegolli, A; Meng, G; Montanari, C; Otwinowski, S; Picchi, P; Pietropaolo, F; Plonski, P; Rappoldi, A; Raselli, G L; Rossella, M; Rubbia, C; Sala, P; Scaramelli, A; Segreto, E; Sergiampietri, F; Stefan, D; Sulej, R; Szarska, M; Terrani, M; Torti, M; Varanini, F; Ventura, S; Vignoli, C; Wang, H; Yang, X; Zalewska, A; Zani, A; Zaremba, K

2014-01-01

The ICARUS T600 detector, the largest liquid Argon Time Projection Chamber (LAr-TPC) realized after many years of RD activities, was installed and successfully operated for 3 years at the INFN Gran Sasso underground Laboratory. One of the most important issues was the need of an extremely low residual electronegative impurity content in the liquid Argon, in order to transport the free electrons created by the ionizing particles with a very small attenuation along the drift path. The solutions adopted for the Argon re-circulation and purification systems have permitted to reach impressive results in terms of Argon purity and a free electron lifetime exceeding 15 ms, corresponding to about 20 parts per trillion of equivalent O2 contamination, a milestone for any future project involving LAr-TPC's and the development of higher detector mass scales.

Resolution studies of a GEM-based TPC

Energy Technology Data Exchange (ETDEWEB)

Killenberg, M.

2006-12-15

Currently there are four different concept studies trying to optimise the detector for the requirements at the ILC. In three of these detector concepts a time projection chamber (TPC) is foreseen as the main tracking device. To achieve the intended spatial resolution of 100 {mu}m, micro pattern gas detectors (MPGD) are considered for gas amplification. The two different MPGDs discussed for the ILC TPC are Micro-Mesh Gaseous Detectors (Micromegas) and Gas Electron Multiplier foils (GEMs). The current thesis shows resolution studies with a TPC prototype equipped with a triple GEM readout structure. A hodoscope made up of silicon strip sensors gives a precision reference track, allowing an unbiased measurement of the spatial resolution. High statistics measurements have been conducted at the DESY test beam facility, which provides positrons with a tunable energy between 1 GeV and 6 GeV. Using the independent measurement of the hodoscope allows systematic studies of the homogeneity of the TPC's electric field. The fluctuations of the field in the chamber's central region were found to be {delta}E/E=8.10{sup -3}. Field distortions have been determined and corrected, reducing the remaining deviations to a level well below the spatial resolution of the TPC. One important task is to reduce the number of ions drifting back into the sensitive volume. Special GEM settings with minimised ion backdrift have been examined with respect to their influence on the spatial resolution and it was found that the spatial resolution is not degraded using these special settings. The TPC prototype has been operated in a 4 T magnetic field, provided by a superconducting solenoid located at DESY Hamburg. Again the spatial resolution measured with the ion backdrift optimised settings is compared to that achieved with nonoptimised settings. In both cases the measured resolution is approximately 130 {mu}m. (orig.)

Resolution studies of a GEM-based TPC

International Nuclear Information System (INIS)

Killenberg, M.

2006-01-01

Currently there are four different concept studies trying to optimise the detector for the requirements at the ILC. In three of these detector concepts a time projection chamber (TPC) is foreseen as the main tracking device. To achieve the intended spatial resolution of 100 μm, micro pattern gas detectors (MPGD) are considered for gas amplification. The two different MPGDs discussed for the ILC TPC are Micro-Mesh Gaseous Detectors (Micromegas) and Gas Electron Multiplier foils (GEMs). The current thesis shows resolution studies with a TPC prototype equipped with a triple GEM readout structure. A hodoscope made up of silicon strip sensors gives a precision reference track, allowing an unbiased measurement of the spatial resolution. High statistics measurements have been conducted at the DESY test beam facility, which provides positrons with a tunable energy between 1 GeV and 6 GeV. Using the independent measurement of the hodoscope allows systematic studies of the homogeneity of the TPC's electric field. The fluctuations of the field in the chamber's central region were found to be ΔE/E=8.10 -3 . Field distortions have been determined and corrected, reducing the remaining deviations to a level well below the spatial resolution of the TPC. One important task is to reduce the number of ions drifting back into the sensitive volume. Special GEM settings with minimised ion backdrift have been examined with respect to their influence on the spatial resolution and it was found that the spatial resolution is not degraded using these special settings. The TPC prototype has been operated in a 4 T magnetic field, provided by a superconducting solenoid located at DESY Hamburg. Again the spatial resolution measured with the ion backdrift optimised settings is compared to that achieved with nonoptimised settings. In both cases the measured resolution is approximately 130 μm. (orig.)

Status of PEP and TPC/2γ

International Nuclear Information System (INIS)

Zapalac, G.

1989-06-01

The TPC/2γ program at PEP has been upgraded by increasing the PEP luminosity and by the adding of a vertex chamber to the TPC detector. These improvements will allow a strong program in B and τ physics, and will contribute to ongoing studies in two-photon physics and hadronization. 10 refs., 3 figs

Prototype of the ALICE Time Projection Chamber (TPC) Field-Cage

CERN Multimedia

2003-01-01

The ALICE Time Projection Chamber (TPC) is the main particle tracking detector in ALICE. Charged particles crossing the gas of the TPC knock electons out of their atoms, which then drift in in the electric field. By measuring the arrival of electrons at the end of the chamber, the TPC will reconstruct the paths of the original charged particles.

Mechanical Properties of Nylon Harp Strings

Science.gov (United States)

Lynch-Aird, Nicolas; Woodhouse, Jim

2017-01-01

Monofilament nylon strings with a range of diameters, commercially marketed as harp strings, have been tested to establish their long-term mechanical properties. Once a string had settled into a desired stress state, the Young’s modulus was measured by a variety of methods that probe different time-scales. The modulus was found to be a strong function of testing frequency and also a strong function of stress. Strings were also subjected to cyclical variations of temperature, allowing various thermal properties to be measured: the coefficient of linear thermal expansion and the thermal sensitivities of tuning, Young’s modulus and density. The results revealed that the particular strings tested are divided into two groups with very different properties: stress-strain behaviour differing by a factor of two and some parametric sensitivities even having the opposite sign. Within each group, correlation studies allowed simple functional fits to be found to the key properties, which have the potential to be used in automated tuning systems for harp strings. PMID:28772858

Mechanical Properties of Nylon Harp Strings

Directory of Open Access Journals (Sweden)

Nicolas Lynch-Aird

2017-05-01

Full Text Available Monofilament nylon strings with a range of diameters, commercially marketed as harp strings, have been tested to establish their long-term mechanical properties. Once a string had settled into a desired stress state, the Young’s modulus was measured by a variety of methods that probe different time-scales. The modulus was found to be a strong function of testing frequency and also a strong function of stress. Strings were also subjected to cyclical variations of temperature, allowing various thermal properties to be measured: the coefficient of linear thermal expansion and the thermal sensitivities of tuning, Young’s modulus and density. The results revealed that the particular strings tested are divided into two groups with very different properties: stress-strain behaviour differing by a factor of two and some parametric sensitivities even having the opposite sign. Within each group, correlation studies allowed simple functional fits to be found to the key properties, which have the potential to be used in automated tuning systems for harp strings.

A Combination of TsHARP and Thin Plate Spline Interpolation for Spatial Sharpening of Thermal Imagery

Directory of Open Access Journals (Sweden)

Xuehong Chen

2014-03-01

Full Text Available There have been many studies and much attention paid to spatial sharpening for thermal imagery. Among them, TsHARP, based on the good correlation between vegetation index and land surface temperature (LST, is regarded as a standard technique because of its operational simplicity and effectiveness. However, as LST is affected by other factors (e.g., soil moisture in the areas with low vegetation cover, these areas cannot be well sharpened by TsHARP. Thin plate spline (TPS is another popular downscaling technique for surface data. It has been shown to be accurate and robust for different datasets; however, it has not yet been attempted in thermal sharpening. This paper proposes to combine the TsHARP and TPS methods to enhance the advantages of each. The spatially explicit errors of these two methods were firstly estimated in theory, and then the results of TPS and TsHARP were combined with the estimation of their errors. The experiments performed across various landscapes and data showed that the proposed combined method performs more robustly and accurately than TsHARP.

The TPC shielding of the CAST experiment

International Nuclear Information System (INIS)

Ruz, J; Luzon, G; Beltran, B; Carmona, J M; Cebrian, S; Gomez, H; Irastorza, I G; Morales, J; Ortiz de Solorzano, A; RodrIguez, A; Villar, J A

2006-01-01

Sunset solar axions traversing the intense magnetic field of the CERN Axion Solar Telescope (CAST) experiment may be detected in a TPC detector, placed at one side of the magnet, as point-like X-rays signals. This signal could be masked, however, by the inhomogeneous radioactive background of materials and experimental site. Here we present the shielding built to reduce and homogenize the radioactive background levels of the TPC detector

A neurological comparative study of the harp seal (Pagophilus groenlandicus) and harbor porpoise (Phocoena phocoena) brain

DEFF Research Database (Denmark)

Walløe, Solveig; Eriksen, Nina; Dabelsteen, Torben

2010-01-01

The cetacean brain is well studied. However, few comparisons have been done with other marine mammals. In this study, we compared the harp seal (Pagophilus groenlandicus) and the harbor porpoise brain (Phocoena phocoena). Stereological methods were applied to compare three areas of interest...... cells, whereas the harp seal have 6.1 × 10(9) neocortical neurons and 17.5 × 10(9) neocortical glial cells. The harbor porpoise have significantly more neurons and glial cells in the auditory cortex than in the visual cortex, whereas the pattern was opposite for the harp seal. These results...... are the first to provide estimates of the number of neurons and glial cells in the neocortex of the harp seal and harbor porpoise brain and offer new data to the comparative field of mammalian brain evolution....

Readout system of TPC/MPD NICA project

Energy Technology Data Exchange (ETDEWEB)

Averyanov, A. V.; Bajajin, A. G.; Chepurnov, V. F.; Cheremukhina, G. A.; Fateev, O. V.; Korotkova, A. M.; Levchanovskiy, F. V.; Lukstins, J.; Movchan, S. A.; Razin, S. V.; Rybakov, A. A.; Vereschagin, S. V., E-mail: vereschagin@jinr.ru; Zanevsky, Yu. V.; Zaporozhets, S. A.; Zruyev, V. N. [Joint Institute for Nuclear Research (Russian Federation)

2015-12-15

The time-projection chamber (TPC) is the main tracking detector in the MPD/NICA. The information on charge-particle tracks in the TPC is registered by the MWPG with cathode pad readout. The frontend electronics (FEE) are developed with use of modern technologies such as application specific integrated circuits (ASIC), field-programmable gate arrays (FPGA), and data transfer to a concentrator via a fast optical interface. The main parameters of the FEE are as follows: total number of channels, ∼95 000; data stream from the whole TPC, 5 GB/s; low power consumption, less than 100 mW/ch; signal to noise ratio (S/N), 30; equivalent noise charge (ENC), <1000e{sup –} (C{sub in} = 10–20 pF); and zero suppression (pad signal rejection ∼90%). The article presents the status of the readout chamber construction and the data acquisition system. The results of testing FEE prototypes are presented.

Individuality in harp seal, Phoca groenlandica, pup vocalizations

NARCIS (Netherlands)

Van Opzeeland, IC; Van Parijs, SM

In gregarious breeders, parents often use individually stereotyped vocalizations as a cue to relocate offspring. Harp seals aggregate in large colonies on pack ice during the whelping season. During the 11-day lactation period, females alternate between periods at sea and attending their pup. If

Online calibration of the ALICE-TPC in LHC-Run 2

Energy Technology Data Exchange (ETDEWEB)

Vorobyev, Ivan [Technische Universitaet Muenchen, Excellence Cluster Universe (Germany); Collaboration: ALICE-Collaboration

2015-07-01

The Time Projection Chamber (TPC) is the main tracking detector at the ALICE Experiment at the LHC. Its performance and calibration directly influence the calibration of other detectors in the ALICE central barrel. To address this issue during the first LHC running period, a two-step offline calibration was employed, in which first the TPC and then the other detectors were calibrated. However, such a scheme will not be feasible for the Run 3 period, because the TPC will run in a continuous readout mode, producing a vast amount of data that needs to be significantly compressed on the fly for data storage. This will require the calibration step to run online within the High Level Trigger environment. In this talk, the online calibration concept and the implementation for the ALICE-TPC already in Run 2 are discussed.

The GAP-TPC

International Nuclear Information System (INIS)

Rossi, B.; Anastasio, A.; Boiano, A.; Cocco, A.G.; Meo, P. Di; Vanzanella, A.; Catalanotti, S.; Covone, G.; Longo, G.; Walker, S.; Fiorillo, G.; Wang, H.; Wang, Y.

2016-01-01

Several experiments have been conducted worldwide, with the goal of observing low-energy nuclear recoils induced by WIMPs scattering off target nuclei in ultra-sensitive, low-background detectors. In the last few decades noble liquid detectors designed to search for dark matter in the form of WIMPs have been extremely successful in improving their sensitivities and setting the best limits. One of the crucial problems to be faced for the development of large size (multi ton-scale) liquid argon experiments is the lack of reliable and low background cryogenic PMTs: their intrinsic radioactivity, cost, and borderline performance at 87 K rule them out as a possible candidate for photosensors. We propose a brand new concept of liquid argon-based detector for direct dark matter search: the Geiger-mode Avalanche Photodiode Time Projection Chamber (GAP-TPC) optimized in terms of residual radioactivity of the photosensors, energy and spatial resolution, light and charge collection efficiency

Magnetic field map for a large TPC prototype

International Nuclear Information System (INIS)

Grefe, Christian

2008-12-01

A new e + e - linear collider with an energy of up to 1000 GeV is currently being planned: the International Linear Collider (ILC). It will allow high precision measurements of the Higgs boson and physics beyond the Standard Model. In the Large Detector Concept (LDC) -which is one of the proposed detector concepts for the ILC- a Time Projection Chamber (TPC) is intended as the main tracking device. Within the EUDET project a large TPC prototype is currently being built as an infrastructure to test different gas amplification and readout technologies. The prototype will be operated in a 1T superconducting solenoid magnet -the PCMAG- at the DESY testbeam area. In order to reach the best possible track reconstruction the magnetic field has to be known very precisely throughout the TPC volume. The magnetic field of PCMAG has been measured in July 2007. In this work the creation of a high precision field map from the measurements is presented. The magnet and modelling techniques for its magnetic field are described. A model of the magnet has been created as a best fit from the measurements and its limitations are investigated. The field map will be included in the reconstruction software for the TPC prototype. (orig.)

Magnetic field map for a large TPC prototype

Energy Technology Data Exchange (ETDEWEB)

Grefe, Christian

2008-12-15

A new e{sup +}e{sup -} linear collider with an energy of up to 1000 GeV is currently being planned: the International Linear Collider (ILC). It will allow high precision measurements of the Higgs boson and physics beyond the Standard Model. In the Large Detector Concept (LDC) -which is one of the proposed detector concepts for the ILC- a Time Projection Chamber (TPC) is intended as the main tracking device. Within the EUDET project a large TPC prototype is currently being built as an infrastructure to test different gas amplification and readout technologies. The prototype will be operated in a 1T superconducting solenoid magnet -the PCMAG- at the DESY testbeam area. In order to reach the best possible track reconstruction the magnetic field has to be known very precisely throughout the TPC volume. The magnetic field of PCMAG has been measured in July 2007. In this work the creation of a high precision field map from the measurements is presented. The magnet and modelling techniques for its magnetic field are described. A model of the magnet has been created as a best fit from the measurements and its limitations are investigated. The field map will be included in the reconstruction software for the TPC prototype. (orig.)

Commissioning and calibration of the ALICE-TPC

Energy Technology Data Exchange (ETDEWEB)

Wiechula, Jens

2009-04-21

ALICE (A Large Ion Collider Experiment), is the dedicated heavy-ion experiment at the Large Hadron Collider (LHC) at CERN. It is optimised to reconstruct and identify the particles created in a lead-lead collision with a centre of mass energy of 5.5 TeV. The main tracking detector is a large-volume time-projection chamber (TPC). With an active volume of about 88m{sup 3} and a total readout area of 32.5 m{sup 2} it is the most challenging TPC ever build. A central electrode divides the 5 m long detector into two drift regions. Each readout side is subdivided into 18 inner and 18 outer multi-wire proportional read-out chambers. The readout area is subdivided into 557568 pads, where each pad is read out by an electronic chain. A complex calibration is needed in order to reach the design position-resolution of the reconstructed particle tracks of about 200 {mu}m. The work at hand presents results of the pedestal and noise behaviour of the front-end electronics (FEE), measurements of the pulse-shaping properties of the FEE using results obtained with a calibration pulser and measurements performed with the laser-calibration system. The data concerned were taken during two phases of the TPC commissioning. First measurements were performed in the clean room where the TPC was built. After the TPC was moved underground and built into the experiment, a second round of commissioning took place. Noise measurements in the clean room revealed a very large fraction of pads with noise values larger than the design specifications. Two modifications helped to reduce the 'ground bounce' effect: A desynchronisation in the the start of the readout of groups of channels and a modification in the grounding scheme of the FEE. Further noise measurements were carried out after the TPC has been moved to the experimental area underground. Here even a larger fraction of channels showed too large noise values. To study the shaping properties of the FEE a calibration pulser was used

Commissioning and calibration of the ALICE-TPC

International Nuclear Information System (INIS)

Wiechula, Jens

2009-01-01

ALICE (A Large Ion Collider Experiment), is the dedicated heavy-ion experiment at the Large Hadron Collider (LHC) at CERN. It is optimised to reconstruct and identify the particles created in a lead-lead collision with a centre of mass energy of 5.5 TeV. The main tracking detector is a large-volume time-projection chamber (TPC). With an active volume of about 88m 3 and a total readout area of 32.5 m 2 it is the most challenging TPC ever build. A central electrode divides the 5 m long detector into two drift regions. Each readout side is subdivided into 18 inner and 18 outer multi-wire proportional read-out chambers. The readout area is subdivided into 557568 pads, where each pad is read out by an electronic chain. A complex calibration is needed in order to reach the design position-resolution of the reconstructed particle tracks of about 200 μm. The work at hand presents results of the pedestal and noise behaviour of the front-end electronics (FEE), measurements of the pulse-shaping properties of the FEE using results obtained with a calibration pulser and measurements performed with the laser-calibration system. The data concerned were taken during two phases of the TPC commissioning. First measurements were performed in the clean room where the TPC was built. After the TPC was moved underground and built into the experiment, a second round of commissioning took place. Noise measurements in the clean room revealed a very large fraction of pads with noise values larger than the design specifications. Two modifications helped to reduce the 'ground bounce' effect: A desynchronisation in the the start of the readout of groups of channels and a modification in the grounding scheme of the FEE. Further noise measurements were carried out after the TPC has been moved to the experimental area underground. Here even a larger fraction of channels showed too large noise values. To study the shaping properties of the FEE a calibration pulser was used. To generate signals in

Performance study of a GEM-TPC prototype using cosmic rays

International Nuclear Information System (INIS)

Li Yulan; Qi Huirong; Li Jin; Gao Yuanning; Li Yuanjing; Yang Zhenwei; Fujii, Keisuke; Matsuda, Takeshi

2008-01-01

Time projection chambers (TPCs) have been successfully used as the central tracking devices in a number of high-energy physics experiments. However, the performance requirements on TPCs for future high-energy physics experiments greatly exceed the abilities of traditional TPCs read out by multi-wire proportional chambers (MWPCs). Micro-pattern gas detectors (MPGDs), such as gas electron multipliers (GEMs) or micromegas, have great potential to improve TPC performance when used as readout detectors. In order to evaluate its feasibility, a GEM-based TPC prototype with a drift length up to 50 cm was designed. Measurements of the spatial resolution of cosmic-ray tracks without and with a magnetic field (B=1 T) are presented. A very good performance is achieved, matching the analytic formula for the spatial resolution of a MPGD-readout TPC. A dedicated study shows that the increase of GEM detector gain can improve the TPC's spatial resolution.

Highly integrated electronics for the star TPC

Energy Technology Data Exchange (ETDEWEB)

Arthur, A.A.; Bieser, F.; Hearn, W.; Kleinfelder, S.; Merrick, T.; Millaud, J.; Noggle, T.; Rai, G.; Ritter, H.G.; Wieman, H. [Lawrence Berkeley Laboratory, CA (United States)

1991-12-31

The concept for the STAR TPC front-end electronics is presented and the progress toward the development of a fully integrated solution is described. It is the goal of the R+D program to develop the complete electronics chain for the STAR central TPC detector at RHIC. It is obvious that solutions chosen e.g. for ALEPH are not adequate for the 150000 channels that need to be instrumented for readout. It will be necessary to perform all the signal processing, digitization and multiplexing directly on the detector in order to reduce per channel cost and the amount of cabling necessary to read out the information. We follow the approach chosen by the EOS TPC project, where the readout electronics on the detector consists of an integrated preamplifier, a hybrid shaping amplifier, an integrated switched capacitor array and a highly multiplexed ADC. The STAR electronics will be further integrated so that approximately 16 channels of the preamplifier, the shaper, the analog store and the ADC will be contained in two integrated circuits located directly on the pad plane.

Status of the ALICE TPC upgrade for high-rate operation

Energy Technology Data Exchange (ETDEWEB)

Gasik, Piotr [TU Muenchen, Physik Department E12, Excellence Cluster ' ' Universe' ' , D-85748, Garching (Germany); Collaboration: ALICE-Collaboration

2015-07-01

A large Time Projection Chamber (TPC) is the main device for tracking and charged particle identification in the ALICE experiment at the CERN LHC. After the second long shutdown in 2018/2019, the LHC will deliver Pb beams colliding at an interaction rate of about 50 kHz, which is about a factor of 100 above the present readout rate of the TPC. This will result in a significant improvement on the sensitivity of rare probes that are considered key observables to characterise the hot and dense QCD matter created in such collisions. In order to make full use of this luminosity, a major upgrade of the TPC is required. It is foreseen to replace the existing MWPC-based readout chambers by Gas Electron Multiplier (GEM) detectors to overcome the rate limitations imposed by the present gated readout scheme. An extensive R and D program has been launched to reach the challenging requirements of the upcoming upgrade of the detector. In this presentation the most recent results are discussed concerning ion backflow suppression, gain stability, energy and dE/dx resolution and stability against discharges. The status of the upgrade of the online calibration and data reduction system, which includes advanced techniques for online corrections of space-charge distortions, as well as the development of a new readout electronics are reported.

Search for H-dibaryon at J-PARC with a Large Acceptance TPC

Directory of Open Access Journals (Sweden)

Sako H.

2014-03-01

Full Text Available H-dibaryon has been predicted as a stable 6-quark color-singlet state. It has been searched for by many experiments but has never been discovered. Recent lattice QCD calculations predict H-dibaryon as a weakly bound or a resonant state close to the LL threshold. E224 and E522 experiments at KEK observed peaks in LL invariant mass spectra near the threshold in (K-, K+ reactions, which were statistically not significant. Therefore, we proposed a new experiment E42 at J-PARC. It will measure decay products of ΛΛ and Λπ-p in a (K-, K+ reaction. We design a large acceptance spectrometer based on a Time Projection Chamber (TPC immersed in a dipole magnetic field. The TPC surrounds a target to cover nearly 4π acceptance, and accepts K- beams up to 106 counts per second. To suppress drift field distortion at high beam rates, we adopt Gas Electron Multipliers (GEMs for electron amplification and a gating grid. We show an overview of the experiment, the design of the spectrometer, and the R&D status of the TPC prototype.

Indirect flat-panel detector with avalanche gain: Fundamental feasibility investigation for SHARP-AMFPI (scintillator HARP active matrix flat panel imager)

International Nuclear Information System (INIS)

Zhao Wei; Li Dan; Reznik, Alla; Lui, B.J.M.; Hunt, D.C.; Rowlands, J.A.; Ohkawa, Yuji; Tanioka, Kenkichi

2005-01-01

An indirect flat-panel imager (FPI) with avalanche gain is being investigated for low-dose x-ray imaging. It is made by optically coupling a structured x-ray scintillator CsI(Tl) to an amorphous selenium (a-Se) avalanche photoconductor called HARP (high-gain avalanche rushing photoconductor). The final electronic image is read out using an active matrix array of thin film transistors (TFT). We call the proposed detector SHARP-AMFPI (scintillator HARP active matrix flat panel imager). The advantage of the SHARP-AMFPI is its programmable gain, which can be turned on during low dose fluoroscopy to overcome electronic noise, and turned off during high dose radiography to avoid pixel saturation. The purpose of this paper is to investigate the important design considerations for SHARP-AMFPI such as avalanche gain, which depends on both the thickness d Se and the applied electric field E Se of the HARP layer. To determine the optimal design parameter and operational conditions for HARP, we measured the E Se dependence of both avalanche gain and optical quantum efficiency of an 8 μm HARP layer. The results were used in a physical model of HARP as well as a linear cascaded model of the FPI to determine the following x-ray imaging properties in both the avalanche and nonavalanche modes as a function of E Se : (1) total gain (which is the product of avalanche gain and optical quantum efficiency); (2) linearity; (3) dynamic range; (4) gain nonuniformity resulting from thickness nonuniformity; and (5) effects of direct x-ray interaction in HARP. Our results showed that a HARP layer thickness of 8 μm can provide adequate avalanche gain and sufficient dynamic range for x-ray imaging applications to permit quantum limited operation over the range of exposures needed for radiography and fluoroscopy

R and D of MPGD-readout TPC for the International Linear Collider experiment

International Nuclear Information System (INIS)

Yonamine, R

2012-01-01

A Time Projection Chamber (TPC) is chosen for the central tracker of the ILD detector, one of two detector concepts planned for the International Linear Collider (ILC). Physics goals at the ILC will require a TPC with a position resolution of 100 μm and superior track separation, which are not achievable with a conventional Multi-Wire Proportional Chamber (MWPC) readout. A MPGD readout offers improved position resolution and track separation due to measuring the signal at the anode and minimization of E × B effect. For several years, the LC TPC collaboration has been developing a MPGD readout using various small TPC prototypes and the Large Prototype TPC that is operated in a test beam at DESY. The MPGD technologies being tested are GEM and Micromegas with resistive charge broadening, with both traditional pad and CMOS pixel readout. Readout modules with both GEM and Micromegas gas amplification have achieved a position resolution on the order of 100 μm at B = 1 T. In this paper we report on the recent R and D toward the ILD TPC.

A large ungated TPC with GEM amplification

Science.gov (United States)

Berger, M.; Ball, M.; Fabbietti, L.; Ketzer, B.; Arora, R.; Beck, R.; Böhmer, F. V.; Chen, J.-C.; Cusanno, F.; Dørheim, S.; García, F.; Hehner, J.; Herrmann, N.; Höppner, C.; Kaiser, D.; Kis̆, M.; Kleipa, V.; Konorov, I.; Kunkel, J.; Kurz, N.; Leifels, Y.; Müllner, P.; Münzer, R.; Neubert, S.; Rauch, J.; Schmidt, C. J.; Schmitz, R.; Soyk, D.; Vandenbroucke, M.; Voss, B.; Walther, D.; Zmeskal, J.

2017-10-01

A Time Projection Chamber (TPC) is an ideal device for the detection of charged particle tracks in a large volume covering a solid angle of almost 4 π. The high density of hits on a given particle track facilitates the task of pattern recognition in a high-occupancy environment and in addition provides particle identification by measuring the specific energy loss for each track. For these reasons, TPCs with Multiwire Proportional Chamber (MWPC) amplification have been and are widely used in experiments recording heavy-ion collisions. A significant drawback, however, is the large dead time of the order of 1 ms per event generated by the use of a gating grid, which is mandatory to prevent ions created in the amplification region from drifting back into the drift volume, where they would severely distort the drift path of subsequent tracks. For experiments with higher event rates this concept of a conventional TPC operating with a triggered gating grid can therefore not be applied without a significant loss of data. A continuous readout of the signals is the more appropriate way of operation. This, however, constitutes a change of paradigm with considerable challenges to be met concerning the amplification region, the design and bandwidth of the readout electronics, and the data handling. A mandatory prerequisite for such an operation is a sufficiently good suppression of the ion backflow from the avalanche region, which otherwise limits the tracking and particle identification capabilities of such a detector. Gas Electron Multipliers (GEM) are a promising candidate to combine excellent spatial resolution with an intrinsic suppression of ions. In this paper we describe the design, construction and the commissioning of a large TPC with GEM amplification and without gating grid (GEM-TPC). The design requirements have driven innovations in the construction of a light-weight field-cage, a supporting media flange, the GEM amplification and the readout system, which are

Spatial resolution studies of a GEM-TPC

Energy Technology Data Exchange (ETDEWEB)

Berger, Martin [TU Muenchen, 85748 Garching (Germany); Collaboration: GEM-TPC-Collaboration

2015-07-01

A GEM-TPC can exploit the intrinsic suppression of back drifting ions from the amplification stage of the GEM (Gas Electron Multiplier) foils to overcome the problem of drift-field distortions in an ungated operation. To explore the possibility of such a continuously running TPC (Time Projection Chamber) a large-size detector was built. This detector, with a drift length of 728 mm and a radius of 308 mm and a total of 10254 electronic channels, was designed as an upgrade for the FOPI experiment at GSI (Darmstadt, Germany) to improve the secondary vertex resolution especially for K{sup 0}{sub S}- and Λ-reconstruction and the PID capabilities. After commissioning a large statistics of cosmic data and beam-target reactions has been collected and the obtained tracks in the TPC have been used to improve the tracking algorithms. During the track finding and fitting procedure a clustering algorithm which takes into account the track topology as well as the full 3D spatial information is employed. The the clustering algorithm, the cluster error calculation and the tracking resolution are discussed in this contribution.

Front-end electronics and readout system for the ILD TPC

CERN Document Server

Hedberg, V; Lundberg, B; Mjörnmark, U; Oskarsson, A; Österman, L; De Lentdecker, G; Yang, Y; Zhang, F

2015-01-01

A high resolution TPC is the main option for a central tracking detector at the future International Linear Collider (ILC). It is planned that the MPGD (Micro Pattern Gas Detector) technology will be used for the readout. A Large Prototype TPC at DESY has been used to test the performance of MPGDs in an electron beam of energies up to 6 GeV. The first step in the technology development was to demonstrate that the MPGDs are able to achieve the necessary performance set by the goals of ILC. For this ’proof of principle’ phase, the ALTRO front-end electronics from the ALICE TPC was used, modified to adapt to MPGD readout. The proof of principle has been verified and at present further improvement of the MPGD technology is going on, using the same readout electronics. The next step is the ’feasibility phase’, which aims at producing front-end electronics comparable in size (few mm2) to the readout pads of the TPC. This development work is based on the succeeding SALTRO16 chip, which combines the analogue ...

TPC spectrometer for measuring the e+ spectrum in μ decay

International Nuclear Information System (INIS)

Kinnison, W.W.

1983-01-01

The Time Projection Chamber (TPC) being used at the Los Alamos Meson Physics Facility (LAMPF) for a high-statistics normal muon-decay experiment is described. It is shown how the experiment will improve upon the limits of the weak-interaction coupling constants by a factor of 5 through the measurement of the positron momentum and direction of emission with respect to the muon-polarization vector for 10 8 decays of stopped, polarized, positive muons. The TPC apparatus is described, and it is shown that even though more work is to be done to improve the detector acceptance and individual coordinate resolutions, for certain track topologies, the TPC already has a momentum resolution of 0.7% (sigma)

TPC cross-talk correction: CERN-Dubna-Milano algorithm and results

CERN Document Server

De Min, A; Guskov, A; Krasnoperov, A; Nefedov, Y; Zhemchugov, A

2003-01-01

The CDM (CERN-Dubna-Milano) algorithm for TPC Xtalk correction is presented and discussed in detail. It is a data-driven, model-independent approach to the problem of Xtalk correction. It accounts for arbitrary amplitudes and pulse shapes of signals, and corrects (almost) all generations of Xtalk, with a view to handling (almost) correctly even complex multi-track events. Results on preamp amplification and preamp linearity from the analysis of test-charge injection data of all six TPC sectors are presented. The minimal expected error on the measurement of signal charges in the TPC is discussed. Results are given on the application of the CDM Xtalk correction to test-charge events and krypton events.

Solid-Liquid Extraction Kinetics of Total Phenolic Compounds (TPC from Red Dates

Directory of Open Access Journals (Sweden)

Bee Lin Chua

2018-01-01

Full Text Available Red dates are one of the most famous herbal plants in making traditional Chinese medicine. They contain large amount of bioactive compounds. The objectives of this research were to optimise the crude extract yield and total phenolic compounds (TPC yield from red dates using response surface methodology (RSM and model the extraction kinetics of TPC yield from red dates. Date fruits were dried in an oven under temperatures 50°C, 60°C, 70°C and 80°C until a constant weight was obtained. The optimum drying temperature was 60°C as it gave the highest crude extract yield and TPC yield. Besides that, single factor experiments were used to determine the optimum range of four extraction parameters which were: liquid-solid ratio (10-30 ml/g; ultrasonic power (70-90%; extraction temperature (50-70°C; and extraction time (40-60min. The optimum range of the four parameters were further optimised using the Box-Behken Design (BBD of RSM. The extraction conditions that gave the highest crude extract yield and TPC yield were chosen. The optimum value for liquid-solid ratio, ultrasonic power, extraction temperature and extraction time were 30ml/g, 70%, 60°C and 60 min respectively. The two equations generated from RSM were reliable and can be used to predict the crude extract yield and TPC yield. The higher the extraction temperature, liquid-solid ratio, and extraction time and lower ultrasonic power, the higher the crude extract and TPC yield. Finally, the results of TPC yield versus time based on the optimum extraction parameters from RSM optimisation were fitted into three extraction kinetic models (Peleg’s model, Page’s model and Ponomaryov’s model. It was found that the most suitable kinetic model to represent the extraction process of TPC from red dates was Page’s model due to its coefficient of determination (R2 was the closest to unity, 0.9663 while its root mean square error (RMSE was the closest to zero, 0.001534.

The Readout Control Unit of the ALICE TPC

CERN Document Server

Lien, J A; Musa, L

2004-01-01

The ALICE Time Projection Chamber (TPC) is the main tracking detector of the central barrel of the ALICE (A Large Ion Collider) Experiment at the Large Hadron Collider (LHC), being constructed at CERN, Geneva. It is a 88 m$^{3}$ cylinder filled with gas and divided into two drift regions by the central electrode located at its axial center. The readout chambers of the TPC are multi-wire proportional chambers with cathode pad readout. About 570 000 pads are read-out by an electronics chain of amplification, digitalization and pre-processing. One of the challenges in designing the TPC for ALICE is the design of Front End Electronics (FEE) to cope with the data rates and the channel occupancy. The Readout Control Unit (RCU), which is presented in this work, is designed to control and monitor the Front End Electronics, and to collect and ship data to the High Level Trigger and the Data Acquisition System, via the Detector Data Link (DDL - optical fibre). The RCU must be capable of reading out up to 200 Mbytes/s f...

Slow Control System for the NIFFTE Collaboration TPC

Science.gov (United States)

Ringle, Erik; Niffte Collaboration Collaboration

2011-10-01

As world energy concerns continue to dominate public policy in the 21st century, the need for cleaner and more efficient nuclear power is necessary. In order to effectively design and implement plans for generation IV nuclear reactors, more accurate fission cross-section measurements are necessary. The Neutron Induced Fission Fragment Tracking Experiment (NIFFTE) collaboration, in an effort to meet this need, has constructed a Time Projection Chamber (TPC) which aims to reduce the uncertainty of the fission cross-section to less than 1%. Using the Maximum Integration Data Acquisition System (MIDAS) framework, slow control measurements are integrated into a single interface to facilitate off-site monitoring. The Hart Scientific 1560 Black Stack will be used with two 2564 Thermistor Scanner Modules to monitor internal temperature of the TPC. A Prologix GPIB to Ethernet controller will be used to interface the hardware with MIDAS. This presentation will detail the design and implementation of the slow control system for the TPC. This work was supported by the U.S. Department of Energy Division of Energy Research.

Results from the STAR TPC system test

International Nuclear Information System (INIS)

Betts, W.

1996-01-01

A system test of various components of the Solenoidal Tracker at RHIC (STAR) detector, operating in concern, has recently come on-line. Communication between a major sub-detector, a sector of the Time Projection Chamber (TPC), and the trigger, data acquisition and slow controls systems has been established, enabling data from cosmic ray muons to be collected. First results from an analysis of the TPC data are presented. These include measurements of system noise, electronic parameters such as amplifier gains and pedestal values, and tracking resolution for cosmic ray muons and laser induced ionization tracks. A discussion on the experience gained in integrating the different components for the system test is also given

The Pixel-TPC. Demonstration of the concept and results

Energy Technology Data Exchange (ETDEWEB)

Lupberger, Michael [Universitaet Bonn (Germany); Collaboration: LCTPC-Deutschland-Collaboration

2016-07-01

A Time Projection Chamber (TPC) is foreseen as tracker for the ILD, one of the two detector concepts at the planned International Linear Collider (ILC). At the TPC endplates, Micromegas or GEMs will be used as gas amplification structure. Besides segmented anodes, also an active endplate with pixel chips, in our experiments the Timepix ASIC, is considered as a readout option. In a photolithographic process a grid has been produced on top of the chip to form a so called InGrid, which is a Micromegas-like gas amplification structure. Several thousand InGrids are necessary to equip a complete TPC endplate. For demonstration of the concept, three endplate modules have been built with a total of 160 InGrids covering an active area of about 300 cm{sup 2}. To read out the 10.5 million channels, the Timepix ASIC was implemented in a general readout system. A dedicated powering scheme, DAQ and online event display were developed by our group. The feasibility of the Pixel-TPC could be proven in a test beam campaign at DESY early 2015. The data has partly been analysed and shows the potential of this new type of detector. An overview of the developments necessary to build the detector is presented followed by impressions from the test beam and some of the results from the data analysis.

Annealing helicase HARP closes RPA-stabilized DNA bubbles non-processively

NARCIS (Netherlands)

Burnham, D.R.; Nijholt, B.; de Vlaminck, I.; Quan, Jinhua; Yusufzai, Timur; Dekker, C.

2017-01-01

We investigate the mechanistic nature of the Snf2 family protein HARP, mutations of which are responsible for Schimke immuno-osseous dysplasia. Using a single-molecule magnetic tweezers assay, we construct RPA-stabilized DNA bubbles within torsionally constrained DNA to investigate the annealing

Behavior of TPC`s in a high particle flux environment

Energy Technology Data Exchange (ETDEWEB)

Etkin, A.; Eiseman, S.E.; Foley, K.J.; Hackenburg, R.W.; Longacre, R.S.; Love, W.A.; Morris, T.W.; Platner, E.D.; Saulys, A.C.; Lindenbaum, S.J. [Brookhaven National Lab., Upton, NY (United States); Chan, C.S.; Kramer, M.A.; Zhao, K.H.; Zhu, Y. [City College of New York, New York (United States); Hallman, T.J.; Madansky, L. [Johns Hopkins Univ., Baltimore, MD (United States); Ahmad, S.; Bonner, B.E.; Buchanan, J.A.; Chiou, C.N.; Clement, J.M.; Mutchler, G.S.; Roberts, J.B. [Bonner Nuclear Lab., Houston, TX (United States)

1991-12-31

TPC`s (Time Projection Chamber) used in E-810 at the TAGS (Alternating Gradient Synchrotron) were exposed to fluxes equivalent to more than 10 minimum ionizing particles per second to find if such high fluxes cause gain changes or distortions of the electric field. Initial results of these and other tests are presented and the consequences for the RHIC (Relativistic Heavy Ion Collider) TPC-based experiments are discussed.

HiRel: Hybrid Automated Reliability Predictor (HARP) integrated reliability tool system, (version 7.0). Volume 3: HARP Graphics Oriented (GO) input user's guide

Science.gov (United States)

Bavuso, Salvatore J.; Rothmann, Elizabeth; Mittal, Nitin; Koppen, Sandra Howell

1994-01-01

The Hybrid Automated Reliability Predictor (HARP) integrated Reliability (HiRel) tool system for reliability/availability prediction offers a toolbox of integrated reliability/availability programs that can be used to customize the user's application in a workstation or nonworkstation environment. HiRel consists of interactive graphical input/output programs and four reliability/availability modeling engines that provide analytical and simulative solutions to a wide host of highly reliable fault-tolerant system architectures and is also applicable to electronic systems in general. The tool system was designed at the outset to be compatible with most computing platforms and operating systems, and some programs have been beta tested within the aerospace community for over 8 years. This document is a user's guide for the HiRel graphical preprocessor Graphics Oriented (GO) program. GO is a graphical user interface for the HARP engine that enables the drawing of reliability/availability models on a monitor. A mouse is used to select fault tree gates or Markov graphical symbols from a menu for drawing.

Development of a time projection chamber using gas electron multipliers (GEM-TPC)

International Nuclear Information System (INIS)

Oda, S.X.; Hamagaki, H.; Ozawa, K.; Inuzuka, M.; Sakaguchi, T.; Isobe, T.; Gunji, T.; Morino, Y.; Saito, S.; Yamaguchi, Y.L.; Sawada, S.; Yokkaichi, S.

2006-01-01

We developed a prototype time projection chamber using gas electron multipliers (GEM-TPC) for high energy heavy ion collision experiments. To investigate its performance, we conducted a beam test with three kinds of gases (Ar(90%)-CH 4 (10%), Ar(70%)-C 2 H 6 (30%) and CF 4 ). Detection efficiency of 99%, and spatial resolution of 79μm in the pad-row direction and 313μm in the drift direction were achieved. The test results show that the GEM-TPC meets the requirements for high energy heavy ion collision experiments. The configuration and performance of the GEM-TPC are described

The HARPS-N archive through a Cassandra, NoSQL database suite?

Science.gov (United States)

Molinari, Emilio; Guerra, Jose; Harutyunyan, Avet; Lodi, Marcello; Martin, Adrian

2016-07-01

The TNG-INAF is developing the science archive for the WEAVE instrument. The underlying architecture of the archive is based on a non relational database, more precisely, on Apache Cassandra cluster, which uses a NoSQL technology. In order to test and validate the use of this architecture, we created a local archive which we populated with all the HARPSN spectra collected at the TNG since the instrument's start of operations in mid-2012, as well as developed tools for the analysis of this data set. The HARPS-N data set is two orders of magnitude smaller than WEAVE, but we want to demonstrate the ability to walk through a complete data set and produce scientific output, as valuable as that produced by an ordinary pipeline, though without accessing directly the FITS files. The analytics is done by Apache Solr and Spark and on a relational PostgreSQL database. As an example, we produce observables like metallicity indexes for the targets in the archive and compare the results with the ones coming from the HARPS-N regular data reduction software. The aim of this experiment is to explore the viability of a high availability cluster and distributed NoSQL database as a platform for complex scientific analytics on a large data set, which will then be ported to the WEAVE Archive System (WAS) which we are developing for the WEAVE multi object, fiber spectrograph.

Some TPC measurements in an oxygen beam at the AGS

International Nuclear Information System (INIS)

Love, W.A.; Etkin, A.; Foley, K.J.; Hackenburg, R.W.; Longacre, R.S.; Morris, T.W.; Platner, E.D.; Saulys, A.C.; Bonner, B.E.; Buchanan, J.A.; Chiou, C.N.; Clement, J.M.; Corcoran, M.D.; Krishna, N.; Kruk, J.W.; Miettinen, H.E.; Mutchler, G.S.; Nessi-Tedaldi, F.; Nessi, M.; Phillips, G.C.; Roberts, J.B.; Chan, C.S.; Kramer, M.A.; Hallman, T.J.; Madansky, L.; Lindenbaum, S.J.

1989-01-01

The principal detector for AGS Experiment 810 is a Time Projection Chamber (TPC) in which it is intended to measure momenta and angles of a major fraction of the charged particles from each light ion collision. This report describes the results of a test of a prototype of the TPC in a beam of (14.6x16=233.6 GeV/c) oxygen ions run in June of this year. (orig.)

Progress on the superconducting magnet for the time projection chamber experiment (TPC) at PEP

International Nuclear Information System (INIS)

Green, M.A.; Eberhard, P.H.; Burns, W.A.

1980-01-01

The TPC (Time Projection Chamber) experiment at PEP will have a two meter inside diameter superconducting magnet which creatests a 1.5 T uniform solenoidal field for the TPC. The superconducting magnet coil, cryostat, cooling system, and the TPC gas pressure vessel (which operatests at 11 atm) were designed to be about two thirds of a radiation length thick. As a result, a high current density coil design was chosen. The magnet is cooled by forced flow two phase helium. The TPC magnet is the largest adiabatically stable superconducting magnet built to date. The paper presents the parameters of the TPC thin solenoid and its subsystems. Tests results from the Spring 1980 cryogenic tes are presented. The topics to be dealt with in the paper are cryogenic services and the tests of magnet subsystems such as the folded current leads. Large thin superconducting magnet technology will be important to large detectors to be used on LEP

Future Upgrade and Physics Perspectives of the ALICE TPC

CERN Document Server

INSPIRE-00033137

The ALICE experiment at the Large Hadron Collider (LHC) proposes major detector upgrades to fully exploit the increase of the luminosity of the LHC in RUN~3 and to extend the physics reach for rare probes at low transverse momentum. The Time Projection Chamber (TPC) is one of the main tracking and PID devices in the central barrel of ALICE. The maximum trigger rate of the TPC is currently limited to about 3.5 kHz by the operation of a gating grid system. In order to make full use of the luminosity in RUN 3, the TPC is foreseen to be operated in an ungated mode with continuous readout. The existing MWPC readout will be replaced by a Micro-Pattern Gaseous Detector (MPGD) based readout, which provides intrinsic ion capture capability without gating. Extensive detector R\\&D employing Gas Electron Multiplier (GEM) and Micro-Mesh Gaseous detector (Micromegas) technologies, and simulation studies to advance the techniques for the corrections of space-charge distortions have been performed since 2012. In this pap...

Electronic Devices for Controlling the Very High Voltage in the ALICE TPC Detector

CERN Document Server

Boccioli, Marco

2007-01-01

The Time Projection Chamber (TPC) is the core of the ALICE experiment at CERN. The TPC Very High Voltage project covers the development of the control system for the power supply that generates the 100kV necessary for the drift field in the TPC. This paper reports on the project progress, introducing the control system architecture from the electronics up to the control level. All the electronic devices will be described, highlighting their communication issues, and the challenges in integrating these devices in a PLC-based control system.

High-cadence spectroscopy of M-dwarfs - II. Searching for stellar pulsations with HARPS

Science.gov (United States)

Berdiñas, Z. M.; Rodríguez-López, C.; Amado, P. J.; Anglada-Escudé, G.; Barnes, J. R.; MacDonald, J.; Zechmeister, M.; Sarmiento, L. F.

2017-08-01

Stellar oscillations appear all across the Hertzsprung-Russell diagram. Recent theoretical studies support their existence also in the atmosphere of M dwarfs. These studies predict for them short periodicities ranging from 20 min to 3 h. Our Cool Tiny Beats (CTB) programme aims at finding these oscillations for the very first time. With this goal, CTB explores the short time domain of M dwarfs using radial velocity data from the High Accuracy Radial velocity Planet Searcher (HARPS)-European Southern Observatory and HARPS-N high-precision spectrographs. Here we present the results for the two most long-term stable targets observed to date with CTB, GJ 588 and GJ 699 (I.e. Barnard's star). In the first part of this work we detail the correction of several instrumental effects. These corrections are especially relevant when searching for subnight signals. Results show no significant signals in the range where M dwarfs pulsations were predicted. However, we estimate that stellar pulsations with amplitudes larger than ˜0.5 m s-1 can be detected with a 90 per cent completeness with our observations. This result, along with the excess of power regions detected in the periodograms, opens the possibility of non-resolved very low amplitude pulsation signals. Next generation more precise instrumentation would be required to detect such oscillations. However, the possibility of detecting pulsating M-dwarf stars with larger amplitudes is feasible due to the short size of the analysed sample. This motivates the need for completeness of the CTB survey.

Data links for the EOS TPC

International Nuclear Information System (INIS)

Bieser, F.; Jones, R.; McParland, C.

1991-01-01

This paper reports on the design and performance of high speed data links and slower configuration control links used between the EOS TPC detector and the data processing electronics. Data rates of 5 MBytes/link are maintained over 30m with optical isolation. Pedestal subtraction, hit detection, and data reordering are performed online

Track reconstruction of normal muon decays in the LAMPF TPC: one working scheme

International Nuclear Information System (INIS)

McKee, R.J.

1983-01-01

A working scheme for track reconstruction of normal muon decays in the LAMPF TPC is here outlined. Muon tracks stopping in the TPC and helical electron tracks from muon decay are both identified and fitted for complete event reconstruction. Because of certain geometrical characteristics of the TPC, novel techniques are deployed to find the tracks. Normal road tracing methods do not work reliably; they are replaced by, among other things, a random search technique that locates the helix's planar projection and a carefully worked-out method for correctly putting each coordinate on its proper turn in the helix

Results on search for a QGP with a TPC magnetic spectrometer at AGS and plans for an ∼4π TPC magnetic spectrometer at RHIC

International Nuclear Information System (INIS)

Lindenbaum, S.J.

1991-01-01

In the first part of this paper a search for a Quark-Gluon Plasma (QGP) with a TPC Magnetic Spectrometer at AGS by the BNL/CCNY/Johns Hopkins/Rice (E-810) Collaboration is discussed. At AGS energies the expected increase in baryon density is near maximum. If a QGP is formed even rarely this approach provides a sensitive method for its detection. We have found some interesting phenomena including strangeness enhancement, multi-Λ and K s 0 events and an increased slope for π - (corresponding to a reduced temperature) in the usual temperature plot for p perpendicular < 0.2 GeV/c. We plan to increase the statistics with the 14.5 GeV/c x A Si ions on targets from light to heavy and then to continue the program with incident Au ions. In Part 2 we discuss the BNL/CCNY/Notre Dame/Rice proposal for an ∼ 4π TPC Magnetic Spectrometer for RHIC which we believe will be a sensitive probe for hadronic QGP signals, and also capable of observing departures from QCD should they occur. 8 refs., 12 figs

Surfactant mediated extraction of total phenolic contents (TPC) and antioxidants from fruits juices.

Science.gov (United States)

Sharma, Shweta; Kori, Shivpoojan; Parmar, Ankush

2015-10-15

The aim of this study was to enhance the extraction of total phenolic contents (TPC) and antioxidants from fruit juices by the application of surfactants formulations instead of conventional solvents (methanol, ethanol and acetone). A variety of fruit infusions: apple red delicious (apple (rd)) (Malus domestica), Mcintosh apple (apple (i)) (Malus pumila), sweet lemon (Citrus limetta) and mango (Magnifera indica) were studied. Effect of water, organic solvents and five different aqueous surfactant formulations viz. SDS, Brij-35, Brij-58, Triton X-100 and Span-40 were explored for the extraction of TPC and determining the antioxidant activity (AA). The TPC and AA (%) were determined using Folin-Ciocalteu (FCA) and DPPH assay, respectively. The effect of surfactant type, concentration and common organic solvents on the extraction of TPC and AA (%) was studied using UV-visible spectrophotometric technique. Among all the extracting systems employed, Brij-58 showed the highest extraction efficiency. Copyright © 2015 Elsevier Ltd. All rights reserved.

Inbetriebnahme und Kalibrierung der ALICE-TPC

CERN Document Server

Wiechula, Jens

2008-01-01

ALICE (A Large Ion Collider Experiment), is the dedicated heavy-ion experiment at the Large Hadron Collider (LHC) at CERN. It is optimised to reconstruct and identify the particles created in a lead-lead collision with a centre of mass energy of 5.5TeV. The main tracking detector is a large-volume time-projection chamber (TPC). With an active volume of about 88m^3 and a total readout area of 32.5m^2 it is the most challenging TPC ever build. A central electrode divides the 5m long detector into two drift regions. Each readout side is subdivided into 18 inner and 18 outer multi-wire proportional read-out chambers. The readout area is subdivide into 557568 pads, where each pad is read out by and electronics chanin. A complex calibration is needed in order to reach the design position-resolution of the reconstructed particle tracks of about 200um. One part of the calibration lies in understanding the electronic-response. The work at hand presents results of the pedestal and noise behaviour of the front-end elect...

The ALICE TPC front end electronics

CERN Document Server

Musa, L; Bialas, N; Bramm, R; Campagnolo, R; Engster, Claude; Formenti, F; Bonnes, U; Esteve-Bosch, R; Frankenfeld, Ulrich; Glässel, P; Gonzales, C; Gustafsson, Hans Åke; Jiménez, A; Junique, A; Lien, J; Lindenstruth, V; Mota, B; Braun-Munzinger, P; Oeschler, H; Österman, L; Renfordt, R E; Ruschmann, G; Röhrich, D; Schmidt, H R; Stachel, J; Soltveit, A K; Ullaland, K

2004-01-01

In this paper we present the front end electronics for the time projection chamber (TPC) of the ALICE experiment. The system, which consists of about 570000 channels, is based on two basic units: (a) an analogue ASIC (PASA) that incorporates the shaping-amplifier circuits for 16 channels; (b) a mixed-signal ASIC (ALTRO) that integrates 16 channels, each consisting of a 10-bit 25-MSPS ADC, the baseline subtraction, tail cancellation filter, zero suppression and multi-event buffer. The complete readout chain is contained in front end cards (FEC), with 128 channels each, connected to the detector by means of capton cables. A number of FECs (up to 25) are controlled by a readout control unit (RCU), which interfaces the FECs to the data acquisition (DAQ), the trigger, and the detector control system (DCS) . A function of the final electronics (1024 channels) has been characterized in a test that incorporates a prototype of the ALICE TPC as well as many other components of the final set-up. The tests show that the ...

GEM Foil Quality Assurance For The ALICE TPC Upgrade

Science.gov (United States)

Brücken, Erik; Hildén, Timo

2018-02-01

The ALICE (A Large Ion Collider Experiment) experiment at the Large Hadron Collider (LHC) at CERN is dedicated to heavy ion physics to explore the structure of strongly interacting matter. The Time Projection Chamber (TPC) of ALICE is a tracking detector located in the central region of the experiment. It offers excellent tracking capabilities as well as particle identification. After the second long shutdown (LS2) the LHC will run at substantially higher luminosities. To be able to increase the data acquisition rate by a factor of 100, the ALICE TPC experiment has to replace the Multi-Wire Proportional Chamber (MWPC) -based readout chambers. The MWPC are operated with gating grid that limits the rate to O(kHz). The new ReadOut Chamber (ROC) design is based on Gas Electron Multiplier (GEM) technology operating in continuous mode. The current GEM productions scheme foresees the production of more than 800 GEM foils of different types. To fulfill the requirements on the performance of the GEM TPC readout, necessitates thorough Quality Assurance (QA) measures. The QA scheme, developed by the ALICE collaboration, will be presented in detail.

GEM Foil Quality Assurance For The ALICE TPC Upgrade

Directory of Open Access Journals (Sweden)

Brücken Erik

2018-01-01

Full Text Available The ALICE (A Large Ion Collider Experiment experiment at the Large Hadron Collider (LHC at CERN is dedicated to heavy ion physics to explore the structure of strongly interacting matter. The Time Projection Chamber (TPC of ALICE is a tracking detector located in the central region of the experiment. It offers excellent tracking capabilities as well as particle identification. After the second long shutdown (LS2 the LHC will run at substantially higher luminosities. To be able to increase the data acquisition rate by a factor of 100, the ALICE TPC experiment has to replace the Multi-Wire Proportional Chamber (MWPC –based readout chambers. The MWPC are operated with gating grid that limits the rate to O(kHz. The new ReadOut Chamber (ROC design is based on Gas Electron Multiplier (GEM technology operating in continuous mode. The current GEM productions scheme foresees the production of more than 800 GEM foils of different types. To fulfill the requirements on the performance of the GEM TPC readout, necessitates thorough Quality Assurance (QA measures. The QA scheme, developed by the ALICE collaboration, will be presented in detail.

Pollutants in harp seals (Phoca groenlandica). I. Organochlorines

Energy Technology Data Exchange (ETDEWEB)

Ronald, K; Frank, R J; Dougan, J L; Frank, R; Braun, H E

1984-09-01

Between 1976 and 1978, 248 harp seals were sampled from 5 locations in the Northwest Atlantic and Arctic for organochlorine (OC) residue analysis in tissue. Blood, kidney, brain, muscle and blubber samples were analysed for PCB, DDT, dieldrin, hexachlorobenzene (HCB), and heptachlor epoxide. Levels were generally greatest in blubber tissue. Overall, mean levels of DDT and PCB were greater than those of other OC. A barrier prevented OC compounds from accumulating in the brain to the level one might expect in lipid tissues. Positive correlations were found between 1: DDT and PCB, 2: DDT and dieldrin, and 3: PCB and deildrin. Male harp seals bioaccumulated DDT, PCB, heptachlor epoxide and dieldrin with age. As a group, adult males sampled in the Gulf of St. Lawrence carried the highest concentrations of all OC, except that chlordane did not appear to bioaccumulate and levels of hexachlorobenzene were minimal. Females generally ceased exhibiting significant bioaccumulation once breeding age was reached, due to transplacental and transmammary residue transfer of OC from mother to pup. There were some significant differences in OC levels between locations with DDT: Gulf greater than Front; PCB: Gulf greater than Front; dieldrin: Gulf greater than Front; heptachlor epoxide: Front greater than Gulf. No significant differences were found, however, when northern locations (Grise Fiord, Northwest Greenland, Pangnirtung) were compared to southern (Gulf, Front) on a group basis.

Data links for the EOS TPC

International Nuclear Information System (INIS)

Bieser, F.; Jones, R.; McParland, C.

1990-10-01

We report on the design and performance of high speed data links and slower configuration control links used between the EOS TPC detector and the data processing electronics. Data rates of 5MBytes/s/link are maintained over 30m with optical isolation. Pedestal subtraction, hit detection, and data reordering are performed online. 3 refs., 1 fig

Development of a high rate TPC. The ALICE TPC upgrade after LS2

Energy Technology Data Exchange (ETDEWEB)

Ball, Markus [Rheinische Friedrich-Wilhelms-Universitaet Bonn (Germany); Collaboration: ALICE-Collaboration

2016-07-01

The ALICE (A Large Ion Collider Experiment at CERN) collaboration plans an upgrade of the detector system during the second long shutdown of the LHC, during which the interaction rate will be increased to 50 kHz for Pb-Pb collisions. This demands operation of the Time Projection Chamber (TPC) in an ungated continuous mode. A conventional gating grid can not be used to prevent ions drifting back into the drift volume. Micro Pattern Gaseous Detectors (MPGD) such as GEMs and Micromegas offer suppression of the ion backflow. To keep distortions due to space-charge at a tolerable level an ion yield of 10 to 20 back drifting ions per incoming electron is required. However, the need for low ion backflow might be in conflict to other key parameters such as the detector performance and stability of the system. Therefore a careful optimisation of all three requirements was needed. Furthermore the large scale capability of the system has to be guaranteed. Test beams have been carried out to study the large scale performance with an Inner Readout Chamber (IROC) equipped with a multiple GEM system. Also an quadruple GEM Outer Readout Chamber (OROC) was assembled and successfully operated being the largest detector of this type. The upgrade of all readout chambers with a quadruple GEM system has started in 2016. The strategy and the work flow of the TPC upgrade are presented.

Tokamak plasma power balance calculation code (TPC code) outline and operation manual

International Nuclear Information System (INIS)

Fujieda, Hirobumi; Murakami, Yoshiki; Sugihara, Masayoshi.

1992-11-01

This report is a detailed description on the TPC code, that calculates the power balance of a tokamak plasma according to the ITER guidelines. The TPC code works on a personal computer (Macintosh or J-3100/ IBM-PC). Using input data such as the plasma shape, toroidal magnetic field, plasma current, electron temperature, electron density, impurities and heating power, TPC code can determine the operation point of the fusion reactor (Ion temperature is assumed to be equal to the electron temperature). Supplied flux (Volt · sec) and burn time are also estimated by coil design parameters. Calculated energy confinement time is compared with various L-mode scaling laws and the confinement enhancement factor (H-factor) is evaluated. Divertor heat load is predicted by using simple scaling models (constant-χ, Bohm-type-χ and JT-60U empirical scaling models). Frequently used data can be stored in a 'device file' and used as the default values. TPC code can generate 2-D mesh data and the POPCON plot is drawn by a contour line plotting program (CONPLT). The operation manual about CONPLT code is also described. (author)

CCD's at TPC

International Nuclear Information System (INIS)

Zeller, M.E.

1977-01-01

The CCD, Charge Coupled Device, is an analog shift register for which application to the readout of particle detectors has recently been realized. These devices can be used to detect optical information directly, providing an automated readout for streamer or other optical chambers, or as a single input shift register, acting in this instance as a delay line for analog information. A description is given of the latter mode of operation and its utility as a readout method for drift chambers. Most of the information contained herein has been obtained from tests performed in connection with PEP TPC project, PEP-4. That detector will employ approximately 10 4 CCD's making it a reasonable testing ground for ISABELLE size detectors

AGS silicon gold collisions measured in the E-810 TPC

International Nuclear Information System (INIS)

Love, W.A.; Etkin, A.; Foley, K.J.; Hackenburg, R.W.; Longacre, R.S.; Morris, T.W.; Platner, E.D.; Saulys, A.C.; Bonner, B.E.; Buchanan, J.A.; Chiou, C.N.; Clement, J.M.; Corcoran, M.D.; Kruk, J.W.; Miettinen, H.E.; Mutchler, G.S.; Nessi, M.; Nessi-Tedaldi, F.; Roberts, J.B.; Chan, C.S.; Kramer, M.A.; Hallman, T.J.; Madansky, L.; Lindenbaum, S.J.

1990-01-01

The tracking detector of AGS Experiment 810 is a three-piece Time Projection Chamber (TPC) intended to measure all charged tracks in the forward hemisphere of the nucleon-nucleon center of mass system, i.e. forward of an angle of about 20 degrees in the lab. Each module of the TPC contains twelve rows of short anode wires which give 3-D space points on each track, but no dE/dx information useable for particle identification. The TPC was operated in a beam of silicon ions at the end of June 1989 and this talk reports the results of analysis of the data taken with a thin gold target in that run. The authors have gathered a similar amount of data from thin copper and silicon targets, the analysis of which is in a less advanced state. The results of the investigation of the neutral strange particle decays appear in a separate contribution by Al Saulys. This paper presents the current state of the analysis of the charged tracks from the silicon gold collisions

Investigations of the long-term stability of a GEM-TPC

Energy Technology Data Exchange (ETDEWEB)

Fedorchuk, Oleksiy [Deutsches Elektronen-Synchrotron (DESY), Notkestrasse 85, 22607 Hamburg (Germany); Universitaet Hamburg, Institut fuer Experimentalphysik, Luruper Chaussee 149, 22761 Hamburg (Germany); Collaboration: LCTPC-Deutschland-Collaboration

2016-07-01

For the International Large Detector (ILD) at the planned International Linear Collider (ILC) a Time Projection Chamber (TPC) is foreseen as the main tracking detector. The gas amplification will be done by Micro Pattern Gaseous Detectors (MPGD). One option is to use Gas Electron Multipliers (GEM).While the applicability of GEMs for the gas amplification in a TPC readout has been shown, the focus of the current research is to improve the high voltage stability and reliability of the readout modules. This is a crucial requirement for the operation in the final ILD TPC. The main focus of the research presented in this talk is on studies of the discharge stability and operational features of large area 22 x 18 cm{sup 2} GEM foils. We present systematic studies of the stability of GEM foils under different operation conditions. These studies include measurements and calculations of the dynamic behavior of charges in the GEM foils after a trip. The results will be used to develop methods to avoid destructive discharges in the final readout module.

Construction and testing of the two meter diameter TPC thin superconducting solenoid

International Nuclear Information System (INIS)

Green, M.A.; Eberhard, P.H.; Ross, R.R.; Taylor, J.D.

1979-08-01

High energy colliding beam physics often requires large detectors which contain large volumes of magnetic field. The TPC (Time Projection Chamber) experiment at PEP will use a 1.5T magnetic field within a cylindrical volume which is 2.04m in diameter bounded by iron poles which are separated by a gap of 3.25m. The TPC magnet, built in 1979 by the Lawrence Berkeley Laboratory (LBL), is the largest high current density superconducting magnet built to date. It is designed to operate at a current density of 7 x 10 8 Am -2 and a stored energy of 11MJ, and it is protected by shorted secondary windings during a quench. The paper describes the basic parameters of the TPC magnet and the results of the first subassembly tests at LBL

Lossy compression of TPC data and trajectory tracking efficiency for the ALICE experiment

International Nuclear Information System (INIS)

Nicolaucig, A.; Ivanov, M.; Mattavelli, M.

2003-01-01

In this paper a quasi-lossless algorithm for the on-line compression of the data generated by the Time Projection Chamber (TPC) detector of the ALICE experiment at CERN is described. The algorithm is based on a lossy source code modeling technique, i.e. it is based on a source model which is lossy if samples of the TPC signal are considered one by one; conversely, the source model is lossless or quasi-lossless if some physical quantities that are of main interest for the experiment are considered. These quantities are the area and the location of the center of mass of each TPC signal pulse, representing the pulse charge and the time localization of the pulse. So as to evaluate the consequences of the error introduced by the lossy compression process, the results of the trajectory tracking algorithms that process data off-line after the experiment are analyzed, in particular, versus their sensibility to the noise introduced by the compression. Two different versions of these off-line algorithms are described, performing cluster finding and particle tracking. The results on how these algorithms are affected by the lossy compression are reported. Entropy coding can be applied to the set of events defined by the source model to reduce the bit rate to the corresponding source entropy. Using TPC simulated data according to the expected ALICE TPC performance, the compression algorithm achieves a data reduction in the range of 34.2% down to 23.7% of the original data rate depending on the desired precision on the pulse center of mass. The number of operations per input symbol required to implement the algorithm is relatively low, so that a real-time implementation of the compression process embedded in the TPC data acquisition chain using low-cost integrated electronics is a realistic option to effectively reduce the data storing cost of ALICE experiment

Particle Identification in Jets and High-Multiplicity pp Events with the ALICE TPC

CERN Document Server

AUTHOR|(SzGeCERN)683272; Vogelsang, Werner

The spectra of identified particles in a collision experiment comprise crucial information about the underlying physical processes. The ALICE experiment has powerful Particle IDentification (PID) capabilities, which are unique at the Large Hadron Collider (LHC). In this thesis, a statistical PID method based on the specific energy loss d$E$/d$x$ in the ALICE Time Projection Chamber (TPC) is developed: the TPC Multi-Template Fit (MTF). The MTF allows for the extraction of identified charged particle spectra in a wide momentum range, which extends from about 150 MeV/$c$ to above 20 GeV/$c$. The TPC PID requires a detailed modelling of the TPC d$E$/d$x$ response for momenta above 2-3 GeV/$c$. A framework is developed that allows for the determination of the model parameters and for evaluating the PID information of charged particles. With the MTF, the transverse momentum $p_{\\mathrm{T}}$ spectra of charged pions, kaons and protons at mid-rapidity ($|\\eta| < 0.9$) are measured for pp collisions at $\\sqrt{s}$ ...

Metal-core pad-plane development for ACTAR TPC

Science.gov (United States)

Giovinazzo, J.; Pibernat, J.; Goigoux, T.; de Oliveira, R.; Grinyer, G. F.; Huss, C.; Mauss, B.; Pancin, J.; Pedroza, J. L.; Rebii, A.; Roger, T.; Rosier, P.; Saillant, F.; Wittwer, G.

2018-06-01

With the recent development of active targets and time projection chambers (ACTAR TPC) as detectors for fundamental nuclear physics experiments, the need arose for charge collection planes with a high density of readout channels. In order to fulfill the mechanical constraints for the ACTAR TPC device, we designed a pad-plane based on a metal-core circuit with an conceptually simple design and routing for signal readout, named FAKIR (in reference to a fakir bed of nails). A test circuit has been equipped with a micro mesh gaseous structure (micromegas) for signal amplification and a dedicated readout electronics. Test measurements have been performed with an 55Fe X-ray source giving an intrinsic energy resolution (FWHM) of 22 ± 1% at 5 . 9 keV, and with a 3-alpha source for which a resolution of about 130 ± 20 keV at 4 . 8 MeV has been estimated. The pad-plane has been mounted into a reduced size demonstrator version of the ACTAR TPC detector, in order to illustrate charged particle track reconstruction. The tests preformed with the X-ray and the 3-alpha sources shows that results obtained from pads signals are comparable to the intrinsic result from the micro-mesh signal. In addition, a simple alpha particle tracks analysis is performed to demonstrate that the pad plane allows a precise reconstruction of the direction and length of the trajectories.

Results from tests of the Delphi TPC prototype

International Nuclear Information System (INIS)

Vilanova, D.

1985-01-01

Results from beam tests of a half-scale sector of the Delphi TPC are presented. The spatial resolution is slightly higher than predicted by Monte Carlo simulations, corresponding to an average value of about 300 μm. (orig.)

Development of a GEM-based high rate TPC

Energy Technology Data Exchange (ETDEWEB)

Neubert, Sebastian; Hoeppner, Christian; Ketzer, Bernhard; Weitzel, Quirin; Paul, Stefan; Woerner, Lisa; Konorov, Igor; Mann, Alexander [Technische Universitaet Muenchen, Physik Department E18, Garching (Germany)

2008-07-01

A TPC is considered as the central tracker of the PANDA experiment, which is currently being planned at the new accelerator complex FAIR at Darmstadt. PANDA is designed as an internal target experiment at the antiproton storage ring HESR. The central tracker has to measure particle trajectories over a wide momentum range (0.1-8 GeV/c) from up to 2.10{sup 7} antiproton-proton annihilations/s. The continuous nature of the antiproton beam makes the use of a traditional ion gate impractical. Owing to their intrinsic ion suppression properties, GEM foils are planned as the amplification stage. A small prototype of this GEM-TPC (diameter 200 mm, drift length 77 mm) has been built and characterized with cosmic muons. Results such as spatial resolution, cluster distributions, and diffusion properties are presented in this talk.

Development of a GEM-based TPC for PANDA

Energy Technology Data Exchange (ETDEWEB)

Hoeppner, Christian; Ketzer, Bernhard; Konorov, Igor; Mann, Alexander; Neubert, Sebastian; Paul, Stephan; Weitzel, Quirin; Woerner, Lisa [Technische Universitaet Muenchen, Physik Department E18, 85748 Garching (Germany)

2008-07-01

A TPC is considered as the central tracker of the PANDA experiment, which is currently being planned at the new accelerator complex FAIR at Darmstadt. PANDA is designed as an internal target experiment at the antiproton storage ring HESR. The central tracker has to measure particle trajectories over a wide momentum range (0.1-8 GeV/c) from up to 2.10{sup 7} antiproton-proton annihilations/s. The continuous nature of the antiproton beam makes the use of a traditional ion gate impractical. Owing to their intrinsic ion suppression properties, GEM foils are planned as the amplification stage. A small prototype of this GEM-TPC (diameter 200 mm, drift length 77 mm) has been built and characterized with cosmic muons. Results such as spatial resolution, cluster distributions, and diffusion properties are presented in this talk.

Performance Evaluation of the COBRA GEM for the Application of the TPC

Science.gov (United States)

Terasaki, Kohei; Hamagaki, Hideki; Gunji, Taku; Yamaguchi, Yorito

2014-09-01

Suppression of the back-drifting ions from avalanche region to drift space (IBF: Ion Backflow) is the key for a Time Projection Chamber (TPC) since IBF easily distorts the drift field. To suppress IBF, Gating Grid system is widely used for the TPC but this limits the data taking rate. Gas Electron Multiplier (GEM) has advantages in the reduction of IBF and high rate capability. By adopting GEM, it is possible to run a TPC continuously under high rate and high multiplicity conditions. Motivated by the study of IBF reduction for RICH with Thick COBRA, which has been developed by F. A. Amero et al., we developed COBRA GEMs for the application of a TPC. With a stack configuration, IBF reaches about 0.1 ~ 0.5%, which is ×5--10 better IBF than the standard GEMs. However, the measured energy resolution with COBRA is 20% (σ) and this is much worse than the resolution with standard GEMs. Measurement of long-time stability of gain indicates that gain of COBRA varies significantly due to charging up effect. Simulation studies based on Garfield++ are performed for understanding quantitatively the reasons of worse energy resolution and instability of gain. In this presentation, we will report the simulation studies together with the measured performance of the COBRA GEM.

Rossiter-McLaughlin observations of 55 Cnc e

DEFF Research Database (Denmark)

Lopez-Morales, Mercedes; Triaud, Amaury H. M. J.; Rodler, Florian

2014-01-01

We present Rossiter-McLaughlin observations of the transiting super-Earth 55 Cnc e collected during six transit events between 2012 January and 2013 November with HARPS and HARPS-N. We detect no radial velocity signal above 35 cm s–1 (3σ) and confine the stellar v sin i to 0.2 ± 0.5 km s–1. The s...

Studies on GEM modules for a Large Prototype TPC for the ILC

International Nuclear Information System (INIS)

Tsionou, Dimitra

2017-01-01

The International Linear Collider (ILC) is a future electron–positron collider with centre of mass energy of 500–1000 GeV. The International Large Detector (ILD) is one of two detector concepts at the ILC. Its high precision tracking system consists of Silicon sub-detectors and a Time Projection Chamber (TPC) equipped with micro-pattern gas detectors (MPGDs). Within the framework of the LCTPC collaboration, a Large Prototype (LP) TPC has been built as a demonstrator. This prototype has been equipped with Gas Electron Multiplier (GEM) modules and studied with electron beams of energies 1–6 GeV at the DESY test beam facility. The performance of the prototype detector and the extrapolation to the ILD TPC is presented here. In addition, ongoing optimisation studies and R&D activities in order to prepare the next GEM module iteration are discussed.

Studies on GEM modules for a Large Prototype TPC for the ILC

Energy Technology Data Exchange (ETDEWEB)

Tsionou, Dimitra, E-mail: dimitra.tsionou@desy.de

2017-02-11

The International Linear Collider (ILC) is a future electron–positron collider with centre of mass energy of 500–1000 GeV. The International Large Detector (ILD) is one of two detector concepts at the ILC. Its high precision tracking system consists of Silicon sub-detectors and a Time Projection Chamber (TPC) equipped with micro-pattern gas detectors (MPGDs). Within the framework of the LCTPC collaboration, a Large Prototype (LP) TPC has been built as a demonstrator. This prototype has been equipped with Gas Electron Multiplier (GEM) modules and studied with electron beams of energies 1–6 GeV at the DESY test beam facility. The performance of the prototype detector and the extrapolation to the ILD TPC is presented here. In addition, ongoing optimisation studies and R&D activities in order to prepare the next GEM module iteration are discussed.

Studies on GEM modules for a large prototype TPC for the ILC

International Nuclear Information System (INIS)

Tsionou, Dimitra

2016-12-01

The International Linear Collider (ILC) is a future electron-positron collider with centre of mass energy of 500-1000 GeV. The International Large Detector (ILD) is one of two detector concepts at the ILC. Its high precision tracking system consists of Silicon sub-detectors and a Time Projection Chamber (TPC) equipped with micro-pattern gas detectors (MPGDs). Within the framework of the LCTPC collaboration, a Large Prototype (LP) TPC has been built as a demonstrator. This prototype has been equipped with Gas Electron Multiplier (GEM) modules and studied with electron beams of energies 1-6 GeV at the DESY test beam facility. The performance of the prototype detector and the extrapolation to the ILD TPC is presented here. In addition, ongoing optimisation studies and R and D; activities in order to prepare the next GEM module iteration are discussed.

The HARPS search for southern extra-solar planets . XXXII. New multi-planet systems in the HARPS volume limited sample: a super-Earth and a Neptune in the habitable zone

Science.gov (United States)

Lo Curto, G.; Mayor, M.; Benz, W.; Bouchy, F.; Hébrard, G.; Lovis, C.; Moutou, C.; Naef, D.; Pepe, F.; Queloz, D.; Santos, N. C.; Segransan, D.; Udry, S.

2013-03-01

The vast diversity of planetary systems detected to date is defying our capability of understanding their formation and evolution. Well-defined volume-limited surveys are the best tool at our disposal to tackle the problem, via the acquisition of robust statistics of the orbital elements. We are using the HARPS spectrograph to conduct our survey of ≈850 nearby solar-type stars, and in the course of the past nine years we have monitored the radial velocity of HD 103774, HD 109271, and BD-061339. In this work we present the detection of five planets orbiting these stars, with msin (i) between 0.6 and 7 Neptune masses, four of which are in two multiple systems, comprising one super-Earth and one planet within the habitable zone of a late-type dwarf. Although for strategic reasons we chose efficiency over precision in this survey, we have the capability to detect planets down to the Neptune and super-Earth mass range as well as multiple systems, provided that enough data points are made available. Based on observations made with the HARPS instrument on the ESO 3.6 m telescope at La Silla (Chile), under the GTO program ID 072.C-0488 and the regular programs: 085.C-0019, 087.C-0831 and 089.C-0732. RV data are only available at the CDS via anonymous ftp to cdsarc.u-strasbg.fr (130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/551/A59

T2K Liquid Argon TPC

Science.gov (United States)

Meregaglia, Anselmo

2006-09-01

A 2 km LAr detector would be an important asset for the T2K experiment since it would play an important part in reducing the systematics and improving the ultimate θ sensitivity. It would also be an important milestone for the LAr TPC technique, providing in-situ R&D and paving the way for future large LAr detectors. Its main features are discussed in this talk.

Simulation of space-charge effects in an ungated GEM-based TPC

Energy Technology Data Exchange (ETDEWEB)

Böhmer, F.V., E-mail: felix.boehmer@tum.de; Ball, M.; Dørheim, S.; Höppner, C.; Ketzer, B.; Konorov, I.; Neubert, S.; Paul, S.; Rauch, J.; Vandenbroucke, M.

2013-08-11

A fundamental limit to the application of Time Projection Chambers (TPCs) in high-rate experiments is the accumulation of slowly drifting ions in the active gas volume, which compromises the homogeneity of the drift field and hence the detector resolution. Conventionally, this problem is overcome by the use of ion-gating structures. This method, however, introduces large dead times and restricts trigger rates to a few hundred per second. The ion gate can be eliminated from the setup by the use of Gas Electron Multiplier (GEM) foils for gas amplification, which intrinsically suppress the backflow of ions. This makes the continuous operation of a TPC at high rates feasible. In this work, Monte Carlo simulations of the buildup of ion space charge in a GEM-based TPC and the correction of the resulting drift distortions are discussed, based on realistic numbers for the ion backflow in a triple-GEM amplification stack. A TPC in the future P{sup ¯}ANDA experiment at FAIR serves as an example for the experimental environment. The simulations show that space charge densities up to 65 fC cm{sup −3} are reached, leading to electron drift distortions of up to 10 mm. The application of a laser calibration system to correct these distortions is investigated. Based on full simulations of the detector physics and response, we show that it is possible to correct for the drift distortions and to maintain the good momentum resolution of the GEM-TPC.

Simulation of space-charge effects in an ungated GEM-based TPC

International Nuclear Information System (INIS)

Böhmer, F.V.; Ball, M.; Dørheim, S.; Höppner, C.; Ketzer, B.; Konorov, I.; Neubert, S.; Paul, S.; Rauch, J.; Vandenbroucke, M.

2013-01-01

A fundamental limit to the application of Time Projection Chambers (TPCs) in high-rate experiments is the accumulation of slowly drifting ions in the active gas volume, which compromises the homogeneity of the drift field and hence the detector resolution. Conventionally, this problem is overcome by the use of ion-gating structures. This method, however, introduces large dead times and restricts trigger rates to a few hundred per second. The ion gate can be eliminated from the setup by the use of Gas Electron Multiplier (GEM) foils for gas amplification, which intrinsically suppress the backflow of ions. This makes the continuous operation of a TPC at high rates feasible. In this work, Monte Carlo simulations of the buildup of ion space charge in a GEM-based TPC and the correction of the resulting drift distortions are discussed, based on realistic numbers for the ion backflow in a triple-GEM amplification stack. A TPC in the future P ¯ ANDA experiment at FAIR serves as an example for the experimental environment. The simulations show that space charge densities up to 65 fC cm −3 are reached, leading to electron drift distortions of up to 10 mm. The application of a laser calibration system to correct these distortions is investigated. Based on full simulations of the detector physics and response, we show that it is possible to correct for the drift distortions and to maintain the good momentum resolution of the GEM-TPC

Heavy ion reaction measurements with the EOS TPC (looking for central collisions with missing energy)

International Nuclear Information System (INIS)

Wieman, H.H.

1994-05-01

The EOS TPC was constructed for complete event measurement of heavy ion collisions at the Bevalac. We report here on the TPC design and some preliminary measurements of conserved event quantities such as total invariant mass, total momentum, total A and Z

A continuous read-out TPC for the ALICE upgrade

Energy Technology Data Exchange (ETDEWEB)

Lippmann, C., E-mail: C.Lippmann@gsi.de

2016-07-11

The largest gaseous Time Projection Chamber (TPC) in the world, the ALICE TPC, will be upgraded based on Micro Pattern Gas Detector technology during the second long shutdown of the CERN Large Hadron Collider in 2018/19. The upgraded detector will operate continuously without the use of a triggered gating grid. It will thus be able to read all minimum bias Pb–Pb events that the LHC will deliver at the anticipated peak interaction rate of 50 kHz for the high luminosity heavy-ion era. New read-out electronics will send the continuous data stream to a new online farm at rates up to 1 TByte/s. A fractional ion feedback of below 1% is required to keep distortions due to space charge in the TPC drift volume at a tolerable level. The new read-out chambers will consist of quadruple stacks of Gas Electron Multipliers (GEM), combining GEM foils with a different hole pitch. Other key requirements such as energy resolution and operational stability have to be met as well. A careful optimisation of the performance in terms of all these parameters was achieved during an extensive R&D program. A working point well within the design specifications was identified with an ion backflow of 0.63%, a local energy resolution of 11.3% (sigma) and a discharge probability comparable to that of standard triple GEM detectors.

T2K Liquid Argon TPC

International Nuclear Information System (INIS)

Meregaglia, Anselmo

2006-01-01

A 2 km LAr detector would be an important asset for the T2K experiment since it would play an important part in reducing the systematics and improving the ultimate θ 13 sensitivity. It would also be an important milestone for the LAr TPC technique, providing in-situ R and D and paving the way for future large LAr detectors. Its main features are discussed in this talk

arXiv GEM Foil Quality Assurance For The ALICE TPC Upgrade

CERN Document Server

INSPIRE-00019412; Hildén, Timo

2018-01-01

The ALICE (A Large Ion Collider Experiment) experiment at the Large Hadron Collider (LHC) at CERN is dedicated to heavy ion physics to explore the structure of strongly interacting matter. The Time Projection Chamber (TPC) of ALICE is a tracking detector located in the central region of the experiment. It offers excellent tracking capabilities as well as particle identification. After the second long shutdown (LS2) the LHC will run at substantially higher luminosities. To be able to increase the data acquisition rate by a factor of 100, the ALICE TPC experiment has to replace the Multi-Wire Proportional Chamber (MWPC) –based readout chambers. The MWPC are operated with gating grid that limits the rate to O(kHz). The new ReadOut Chamber (ROC) design is based on Gas Electron Multiplier (GEM) technology operating in continuous mode. The current GEM productions scheme foresees the production of more than 800 GEM foils of different types. To fulfill the requirements on the performance of the GEM TPC readout, nec...

Mesures de production de la particule neutre et étrange $K^{0}_{S}$ dans l'expérience HARP

CERN Document Server

Prior, Gersende; Blondel, A

2005-01-01

The hadron production experiment HARP (PS214) carried out a programme of measurements of secondary hadrons at the European Organization for Nuclear Research (CERN) proton synchrotron (PS) during the years 2001 and 2002. It serves several purposes. On one side there is a need to acquire knowledge of pion yields for an optimal design of the proposed neutrino factories and superbeams. On the other one, we have to improve substantially the calculation of the atmospheric neutrino flux, used by past and forthcoming experiments designed to measure neutrino oscillations. HARP data will also provide a general input for simulation of particles traversing matter, as well as neutrino beam predictions for the K2K and MiniBooNE experiments. The subject of this thesis is to provide strange particle production, K0S, measurements, from HARP data. This study is of interest because, for neutrino beams, the charged kaon contamination induces an electron-neutrino type background in the muon-neutrino beam. The knowledge of such a ...

Some TPC [Time Projection Chamber] measurements in an oxygen beam at the AGS

International Nuclear Information System (INIS)

Love, W.A.; Bonner, B.E.; Buchanan, J.A.

1988-01-01

The principal detector for AGS Experiment 810 is a Time Projection Chamber (TPC) in which it is intended to measure momenta and angles of a major fraction of the charged particles from each light ion collision. This report describes the results of a test of a prototype of the TPC in a beam of (14.6 /times/ 16 = 233.6 GeV/c) oxygen ions run in June of this year

Building a large-area GEM-based readout chamber for the upgrade of the ALICE TPC

CERN Document Server

Gasik, Piotr

2017-01-01

A large Time Projection Chamber (TPC) is the main device for tracking and charged-particle identification in the ALICE experiment at the CERN LHC. After the second long shutdown in 2019-2020, the LHC will deliver Pb beams colliding at an interaction rate up to 50 kHz, which is about a factor of 100 above the present read-out rate of the TPC. To fully exploit the LHC potential the TPC will be upgraded based on the Gas Electron Multiplier (GEM) technology. A prototype of an ALICE TPC Outer Read-Out Chamber (OROC) was equipped with twelve large-size GEM foils as amplification stage to demonstrate the feasibility of replacing the current Multi Wire Proportional Chambers with the new technology. With a total area of $\\sim$0.76 m$^2$ it is the largest GEM-based detector built to date. The GEM OROC was installed within a test field cage and commissioned with radioactive sources.

Building a large-area GEM-based readout chamber for the upgrade of the ALICE TPC

Energy Technology Data Exchange (ETDEWEB)

Gasik, P. [Physik Department E62, Technische Universität München, Garching (Germany); Excellence Cluster ‘Origin and Structure of the Universe’, Garching (Germany)

2017-02-11

A large Time Projection Chamber (TPC) is the main device for tracking and charged-particle identification in the ALICE experiment at the CERN LHC. After the second long shutdown in 2019–2020, the LHC will deliver Pb beams colliding at an interaction rate up to 50 kHz, which is about a factor of 100 above the present read-out rate of the TPC. To fully exploit the LHC potential the TPC will be upgraded based on the Gas Electron Multiplier (GEM) technology. A prototype of an ALICE TPC Outer Read-Out Chamber (OROC) was equipped with twelve large-size GEM foils as amplification stage to demonstrate the feasibility of replacing the current Multi Wire Proportional Chambers with the new technology. With a total area of ∼0.76 m{sup 2} it is the largest GEM-based detector built to date. The GEM OROC was installed within a test field cage and commissioned with radioactive sources.

Building a large-area GEM-based readout chamber for the upgrade of the ALICE TPC

International Nuclear Information System (INIS)

Gasik, P.

2017-01-01

A large Time Projection Chamber (TPC) is the main device for tracking and charged-particle identification in the ALICE experiment at the CERN LHC. After the second long shutdown in 2019–2020, the LHC will deliver Pb beams colliding at an interaction rate up to 50 kHz, which is about a factor of 100 above the present read-out rate of the TPC. To fully exploit the LHC potential the TPC will be upgraded based on the Gas Electron Multiplier (GEM) technology. A prototype of an ALICE TPC Outer Read-Out Chamber (OROC) was equipped with twelve large-size GEM foils as amplification stage to demonstrate the feasibility of replacing the current Multi Wire Proportional Chambers with the new technology. With a total area of ∼0.76 m 2 it is the largest GEM-based detector built to date. The GEM OROC was installed within a test field cage and commissioned with radioactive sources.

‘L’ORAGE DES PASSIONS’: EXPRESSING EMOTION ON THE EIGHTEENTH-CENTURY FRENCH SINGLE-ACTION HARP

Directory of Open Access Journals (Sweden)

Hannah Lane

2014-12-01

Full Text Available The single-action harp was introduced to France in the mid-eighteenth century. The instrument’s popularity reached its zenith in pre-revolutionary Paris as evidenced by the large number of method books and original compositions published for the instrument during this time. One of the first published references to this instrument was an entry in Diderot’s iconic Encyclopédie (1751-­1772 where the author states that the instrument is ‘most suited to expressing tenderness and pain than the other emotions of the soul’. Through reading across key contemporaneous pedagogical, literary and musical sources, with a particular focus on those of influential harpist, writer and pedagogue Stéphanie-Félicité de Genlis (née Du Crest 1746-1830, this paper interrogates how these emotions were performed and expressed on the single-action harp. Recent scholarship has focused on the instrument’s social and gender role, in particular its radical feminisation, in which Genlis has been positioned as a major influence. This article builds upon this research to consider the gendered nature of emotions as expressed on the single-action harp as well as contextualising the instrument’s unique mode of musical-emotional expression within the new musical aesthetic of the late eighteenth century, the Galant and Empfindsamer styles.

The NA36 time projection chamber: An interim report on a TPC designed for a relativistic heavy ion experiment

International Nuclear Information System (INIS)

Diebold, G.E.

1987-01-01

Since its conception in the early 1970s, the Time Projection Chamber (TPC) has found application in several areas of particle physics ranging from e + e - collider experiments to rare decay studies of lepton nonconservation. A new and promising area of application for the TPC is the study of relativistic heavy ion collisions (RHIC). Presented here is an interim report on the first TPC for this field of physics, the NA36 TPC, being developed by Berkeley (LBL) for RHIC at the CERN SPS. Emphasis is placed on the operational and design considerations implemented to optimize the performance of the NA36 TPC in the study of central rapidity strange baryons produced in RHIC. The NA36 TPC volume is rectangular with an endcap area 0.5 m x 1.0 m and a maximum drift distance of 0.5 m. The drift volume is filled with Ar-CH 4 (9%) at one atmosphere. A total of 6400 channels of time digitizing electronics instrument 66% of the endcap in a wedge shaped area matched to fixed target kinematics. 6 refs., 5 figs

Dysregulation of lysosomal morphology by pathogenic LRRK2 is corrected by TPC2 inhibition.

Science.gov (United States)

Hockey, Leanne N; Kilpatrick, Bethan S; Eden, Emily R; Lin-Moshier, Yaping; Brailoiu, G Cristina; Brailoiu, Eugen; Futter, Clare E; Schapira, Anthony H; Marchant, Jonathan S; Patel, Sandip

2015-01-15

Two-pore channels (TPCs) are endolysosomal ion channels implicated in Ca(2+) signalling from acidic organelles. The relevance of these ubiquitous proteins for human disease, however, is unclear. Here, we report that lysosomes are enlarged and aggregated in fibroblasts from Parkinson disease patients with the common G2019S mutation in LRRK2. Defects were corrected by molecular silencing of TPC2, pharmacological inhibition of TPC regulators [Rab7, NAADP and PtdIns(3,5)P2] and buffering local Ca(2+) increases. NAADP-evoked Ca(2+) signals were exaggerated in diseased cells. TPC2 is thus a potential drug target within a pathogenic LRRK2 cascade that disrupts Ca(2+)-dependent trafficking in Parkinson disease. © 2015. Published by The Company of Biologists Ltd.

pesticide residues in water from tpc sugarcane plantations

African Journals Online (AJOL)

ABSTRACT. We report herein, the analysis of water samples collected from TPC Sugarcane Plantation and its environs in Kilimanjaro region, which is the earliest intensive user of pesticides in Tanzania. A total of 50 water samples collected from 18 sampling sites between 2000 and 2001 were analyzed for pesticide ...

Peach Bottom Turbine Trip Simulations with RETRAN Using INER/TPC BWR Transient Analysis Method

International Nuclear Information System (INIS)

Kao Lainsu; Chiang, Show-Chyuan

2005-01-01

The work described in this paper is benchmark calculations of pressurization transient turbine trip tests performed at the Peach Bottom boiling water reactor (BWR). It is part of an overall effort in providing qualification basis for the INER/TPC BWR transient analysis method developed for the Kuosheng and Chinshan plants. The method primarily utilizes an advanced system thermal hydraulics code, RETRAN02/MOD5, for transient safety analyses. Since pressurization transients would result in a strong coupling effect between core neutronic and system thermal hydraulics responses, the INER/TPC method employs the one-dimensional kinetic model in RETRAN with a cross-section data library generated by the Studsvik-CMS code package for the transient calculations. The Peach Bottom Turbine Trip (PBTT) tests, including TT1, TT2, and TT3, have been successfully performed in the plant and assigned as standards commonly for licensing method qualifications for years. It is an essential requirement for licensing purposes to verify integral capabilities and accuracies of the codes and models of the INER/TPC method in simulating such pressurization transients. Specific Peach Bottom plant models, including both neutronics and thermal hydraulics, are developed using modeling approaches and experiences generally adopted in the INER/TPC method. Important model assumptions in RETRAN for the PBTT test simulations are described in this paper. Simulation calculations are performed with best-estimated initial and boundary conditions obtained from plant test measurements. The calculation results presented in this paper demonstrate that the INER/TPC method is capable of calculating accurately the core and system transient behaviors of the tests. Excellent agreement, both in trends and magnitudes between the RETRAN calculation results and the PBTT measurements, shows reliable qualifications of the codes/users/models involved in the method. The RETRAN calculated peak neutron fluxes of the PBTT

Studies of characteristics of triple GEM detector for the ALICE-TPC upgrade

International Nuclear Information System (INIS)

Patra, Rajendra Nath; Singaraju, R.N.; Ahammed, Z.; Nayak, T.K.; Biswas, S.

2015-01-01

Gas Electron Multiplier (GEM) is a novel gas detector in the field of radiation detection. GEM detectors have tremendous advantages over other types gas detectors like high rate handling capability with high efficiency and very low ion back flow (IBF). These detectors are most suitable for the use in the future experiments in high-energy proton-proton and heavy-ion collisions at the Large Hadron Collider (LHC) at CERN and Facility for Antiproton and Ion Research (FAIR) at GSI. A Large Ion Collider Experiment (ALICE) at the LHC is a dedicated experiment for the study of Quark Gluon Plasma (QGP). In few years, the data taking rate for Pb-Pb collisions will increase by 100 times to 50 KHz. The ALICE Time Projection Chamber (TPC) is the main tracking detector in ALICE. It is planned that by the year 2018, GEM detectors will replace the present readout planes of TPC. The goal of the present study is to characterize the GEM detector to achieve the performance goal of the TPC

A radiation tolerance study of the ALICE TPC Readout Control Unit 2

CERN Document Server

Zhao, Chengxin; Balk, Helge; Alme, Johan

2017-11-17

ALICE is a general-purpose detector that is designed to study the physics of quark-gluon plasma. The Time Projection Chamber (TPC) is one of the major detectors of ALICE. The TPC electronics consists of 4356 Front-end cards (FECs), which are controlled by 216 Readout Control Units (RCU). Each RCU connects to between 18 and 25 FECs using a multi-drop bus. In LHC Run1, the Readout Control Unit 1 (RCU1) performed even better than specification. However, in Run2 the energy of colliding beams is increased from 8 TeV to 14 TeV (maximum value) and higher luminosity, which leads to larger event size and higher radiation load on the electronics. As a solution, the Readout Control Unit 2 (RCU2) is designed to provide faster readout speed and improved radiation tolerance with respect to the RCU1. The RCU2 is conceptually similar to the RCU1 and it reuses the existing infrastructure and readout architecture of the TPC electronics. However, the multi-drop bus is split into four branches from the two branches and the bandw...

Simulation and Calibration of the ALICE TPC including innovative Space Charge Calculations

CERN Document Server

Rossegger, S; Riegler, W; Betev, L

2009-01-01

ALICE is one of the four main particle detectors located around the LHC accelerator at CERN. It is particularly designed to study the physics of the quark-gluon plasma by means of nucleus--nucleus collisions at center-of-mass energies up to 5.5 TeV per nucleon pair. A Time-Projection Chamber (TPC) was chosen to be its central-sub-detector due to its low mass properties and its capabilities to provide a robust and accurate Particle Identification even within ultra-high multiplicity environments (up to 8000 tracks per unit of eta). To achieve the required physics performance, the space point resolution of the TPC must be in the order of 0.2 mm. Due to its gigantic size of 5~m in diameter and 5~m in length, corrections for static as well as dynamic effects are indispensable in order to accomplish the design goal. The research presented covers all major issues relevant for the final calibration and therefore the enhancement of the TPC performance in terms of resolution. The main focus was to distinguish between t...

Rebuttal to ‘Comments on “The HARP Time Projection Chamber Characteristics and physics performance”’

CERN Document Server

Ammosov, V; Bolshakova, A; Boyko, I; Chelkov, G; Dedovitch, D; De Min, A; Elagin, A; Gapienko, V; Gostkin, M; Guskov, A; Koreshev, V; Krumshtein, Z; Linssen, L; Nefedov, Yu; Nikolaev, K; Semak, A; Sviridov, Yu; Usenko, E; Wotschack, J; Zaets, V; Zhemchugov, A

2008-01-01

We categorically reject the accusations by the ‘HARP Collaboration’ that we plagiarized their work. Out of their 27 comments on our work, 26 are either wrong, or inappropriate, or without substance.

Meeting fronthaul challenges of future mobile network deployments — The HARP approach

DEFF Research Database (Denmark)

Dittmann, Lars; Christiansen, Henrik Lehrmann; Checko, Aleksandra

2014-01-01

In future mobile networks aggregation at different levels is necessary but at the same time imposes challenges that mandate looking into new architectures. This paper presents the design consideration approach for a C-RAN based mobile aggregation network used in the EU HARP project....... With this architecture fronthaul aggregation is performed which might be an option for future generation of mobile networks....

Topological signature in the NEXT high pressure xenon TPC

Science.gov (United States)

Ferrario, Paola; NEXT Collaboration

2017-09-01

The NEXT experiment aims to observe the neutrinoless double beta decay of 136Xe in a high-pressure xenon gas TPC using electroluminescence to amplify the signal from ionization. One of the main advantages of this technology is the possibility to use the topology of events with energies close to Qββ as an extra tool to reject background. In these proceedings we show with data from prototypes that an extra background rejection factor of 24.3 ± 1.4 (stat.)% can be achieved, while maintaining an efficiency of 66.7 ± 1.% for signal events. The performance expected in NEW, the next stage of the experiment, is to improve to 12.9% ± 0.6% background acceptance for 66.9% ± 0.6% signal efficiency.

The ICARUS 50 1 LAr TPC in the CERN $\

CERN Document Server

Arneodo, F.; De Mitri, I.; Mazza, D.; Parlati, S.; Petrera, S.; Piano Mortari, Giovanni; Verdecchia, M.; Benetti, P.; Borio Di Tigliole, A.; Calligarich, E.; Cesana, E.; Dolfini, R.; Mauri, F.; Montanari, C.; Rappoldi, A.; Raselli, G.L.; Terrani, M.; Torre, P.; Vignoli, C.; Bettini, A.; Carpanese, C.; Centro, S.; Pepato, A.; Pietropaolo, F.; Ventura, S.; Bonesini, M.; Boschetti, B.; Calvi, M.; Curioni, A.; Cavalli, D.; Ferrari, A.; Ferrari, P.; Negri, P.; Paganoni, M.; Pullia, A.; Sala, P.; Ragazzi, S.; Redaelli, Nicola Giuseppe; Tabarelli De Fatis, T.; Terranova, F.; Tonazzo, A.; Casagrande, F.; Cennini, P.; Puccini, A.; Rubbia, A.; Rubbia, C.; Revol, J.P.; Cline, D.; Matthey, C.; Otwinowski, S.; Park, J.; Wang, H.; Woo, J.; Givoletti, J.; Lamarina, A.; Periale, R.; Picchi, P.; Mannocchi, G.; Periale, L.; Suzuki, S.; Sergiampietri, F.

1999-01-01

The 50 litre liquid Argon TPC is a detector built and successfully operated at CERN for R&D purposes within the ICARUS programme. In the year 1997 it has been exposed at the CERN neutrino beam for the entire SPS neutrino run period as proposed and approved at the SPSLC of January 1997. The detector, complemented with scintillators acting as veto, trigger counters and pre-shower counters, was installed in front of the NOMAD detector. The year 1997 was scheduled to be the last for the operation of the West Area Neutrino Facility. It was important to take this last opportunity for a parasitic exposure, which did not interfere with running experiments, of an already existing and operating liquid Argon TPC. As we had expected, the collected data brought important information for a better understanding of the performance of liquid Argon TPCs which should be useful for the entire ICARUS program. (9 refs).

Structure of Voltage-gated Two-pore Channel TPC1 from Arabidopsis thaliana

Science.gov (United States)

Guo, Jiangtao; Zeng, Weizhong; Chen, Qingfeng; Lee, Changkeun; Chen, Liping; Yang, Yi; Cang, Chunlei; Ren, Dejian; Jiang, Youxing

2015-01-01

Two-pore channels (TPCs) contain two copies of a Shaker-like six-transmembrane (6-TM) domain in each subunit and are ubiquitously expressed in both animals and plants as organellar cation channels. Here, we present the first crystal structure of a vacuolar two-pore channel from Arabidopsis thaliana, AtTPC1, which functions as a homodimer. AtTPC1 activation requires both voltage and cytosolic Ca2+. Ca2+ binding to the cytosolic EF-hand domain triggers conformational changes coupled to the pair of pore-lining inner helices (IS6 helices) from the first 6-TM domains, whereas membrane potential only activates the second voltage-sensing domain (VSD2) whose conformational changes are coupled to the pair of inner helices (IIS6 helices) from the second 6-TM domains. Luminal Ca2+ or Ba2+ can modulate voltage activation by stabilizing VSD2 in the resting state and shifts voltage activation towards more positive potentials. Our Ba2+ bound AtTPC1 structure reveals a voltage sensor in the resting state, providing hitherto unseen structural insight into the general voltage-gating mechanism among voltage-gated channels. PMID:26689363

Future prospects of the TPC idea

Energy Technology Data Exchange (ETDEWEB)

Nygren, D R [California Univ., Berkeley (USA). Lawrence Berkeley Lab.

1981-04-01

General aspects affecting TPC size, readout plane characteristics and operation in the LEP environment are presented, with the general conclusion that modest improvements relative to PEP-4 can be realized in several areas. The problem of positive ion reduction is discussed according to two qualitatively new operating modes, asynchronous and synchronous gating. Either gating mode appears to offer a means to eliminate almost completely the ion return flux. Some speculative ideas involving 3-component gas mixtures, low-mass components and parallel plane geometry are presented as future possibilities.

Contribution of a Liquid Argon TPC to T2K Neutrino Experiment

Science.gov (United States)

Meregaglia, A.; Rubbia, A.

2006-08-01

A 2 km LAr detector would be an important asset for the T2K experiment. Different physics scenarios are considered and for each one the role of a LAr TPC in enhancing the ultimate sensitivity on theta 13 is studied. The large sample of neutrino interactions in the GeV region would provide crucial information for the study of different types of reactions and of nuclear effects, whereas the inner target would give a direct measurement of the cross sections ratio between Water and Argon. Such a detector would also be an important milestone for the LAr TPC technique providing an extremely valuable experience for future large LAr detectors.

AGS silicon gold collisions measured in the E-810 TPC [Time Projection Chamber

International Nuclear Information System (INIS)

Bonner, B.E.; Buchanan, J.A.; Chiou, C.N.; Clement, J.M.; Corcoran, M.D.; Kruk, J.W.; Miettinen, H.E.; Mutchler, G.S.; Nessi, M.; Nessi-Tedaldi, F.; Roberts, J.B.; Chan, C.S.; Kramer, M.A.; Etkin, A.; Foley, K.J.; Hackenburg, R.W.; Longacre, R.S.; Love, W.A.; Morris, T.W.; Platner, E.D.; Saulys, A.C.; Hallman, T.J.; Madansky, L.; Lindenbaum, S.J.

1990-01-01

The tracking detector of AGS Experiment 810 is a three-piece Time Projection Chamber (TPC) intended to measure all charged tracks in the forward hemisphere of the nucleon-nucleon center of mass system, i.e. forward of an angle of about 20 degrees in the lab. Each module of the TPC contains twelve rows of short anode wires which give 3-D space points on each track, but no dE/dx information useable for particle identification. The TPC was operated in a beam of silicon ions at the end of June 1989 and this talk reports the results of analysis of the data taken with a thin gold target in that run. We have gathered a similar amount of data from thin copper and silicon targets, the analysis of which is in a less advanced state. The results of our investigation of the neutral strange particle decays appear in a separate contribution by Al Saulys. This paper presents the current state of the analysis of the charged tracks from the silicon gold collisions. 1 ref., 15 figs

Lossy compression of TPC data and trajectory tracking efficiency for the ALICE experiment

CERN Document Server

Nicolaucig, A; Mattavelli, M

2003-01-01

In this paper a quasi-lossless algorithm for the on-line compression of the data generated by the Time Projection Chamber (TPC) detector of the ALICE experiment at CERN is described. The algorithm is based on a lossy source code modeling technique, i.e. it is based on a source model which is lossy if samples of the TPC signal are considered one by one; conversely, the source model is lossless or quasi-lossless if some physical quantities that are of main interest for the experiment are considered. These quantities are the area and the location of the center of mass of each TPC signal pulse, representing the pulse charge and the time localization of the pulse. So as to evaluate the consequences of the error introduced by the lossy compression process, the results of the trajectory tracking algorithms that process data off-line after the experiment are analyzed, in particular, versus their sensibility to the noise introduced by the compression. Two different versions of these off- line algorithms are described,...

First results from the CERES radial TPC

International Nuclear Information System (INIS)

Marin, A.; Agakichiev, G.; Appelshaeuser, H.; Baur, R.; Belaga, V.; Bell, R.; Braun-Munzinger, P.; Ceretto, F.; Cherlin, A.; Damjanovic, S.; Dietel, T.; Drees, A.; Ernst, P.; Esumi, S.I.; Filimonov, K.; Fraenkel, Z.; Gnaenski, A.; Garabatos, C.; Glaessel, P.; Hanzal, V.; Hausmann, M.; Hering, G.; Hrivnacova, I.; Holl, P.; Kushpil, V.; Lenkeit, B.; Messer, M.; Milov, A.; Miskowiec, D.; Panebrattsev, Y.; Petracek, V.; Pfeiffer, A.; Rak, J.; Ravinovich, I.; Razin, S.; Rehak, P.; Richter, M.; Saveljic, N.; Schaefer, E.; Schmitz, W.; Schukraft, J.; Seipp, W.; Sharma, A.; Shimansky, S.; Slivova, J.; Socol, E.; Specht, H.J.; Stachel, J.; Stiller, P.; Sumbera, M.; Tilsner, H.; Tserruya, I.; Voigt, C.; Voloshin, S.; Wessels, J.P.; Wienold, T.; Windelband, B.; Wurm, J.P.; Xie, W.; Yurevich, V.

1999-01-01

The CERES/NA45 experiment at the CERN SPS was upgraded in 1998 by the addition of a cylindrical Time Projection Chamber. The aim is to improve the mass resolution of e + e - pairs in the ρ/ω/phi region to Δm/m < 2%. A progress report is given on the TPC performance during the 1998 commissioning runs (laser rays, beam halo muons, and particles produced by proton/π and lead beams hitting Pb and Au targets)

Organochlorine residues in harp seals, Phoca groenlandica, from the Gulf of St. Lawrence and Hudson Strait: An evaluation of contaminant concentrations and burdens

Energy Technology Data Exchange (ETDEWEB)

Beck, G.G.; Smith, T.G. (Dept. of Fisheries and Oceans, Nanaimo, BC (Canada)); Addison, R.F. (Dept. of Fisheries and Oceans, Sidney, BC (Canada))

1994-01-01

Organochlorine contaminant concentrations and burdens were evaluated in blubber samples from 50 harp seals (Phoca groenlandica) obtained from the estuary and northern Gulf of St. Lawrence and Hudson Strait, Canada between December 1988 and December 1989. The concentration and burden of polychlorinated biphenyls (PCBs) increased significantly during the winter months for males occupying the St. Lawrence estuary. The potential for rapid accumulation of contaminants in the estuary was also observed among females: nine postpartum females (1 month after weaning) had higher organochlorine levels than prepartum females from the same location. The lowest observed contaminant concentrations and burdens were in seals from Hudson Strait in autumn. In winter specimens, males had DDT and PCB concentrations about 4 and 2 times as great, respectively, as females of similar age distribution and collection date. Congeners with IUPAC Nos. 138 and 153 accounted for more than 50% of total identifiable PCBs, which is consistent with their prevalence in other marine biota. The concentration of PCBs has declined and the percent p,p'-DDE of total DDT has increased between 1982 and the present study. Unlike the beluga whale (Delphinapterus leucas), harp seals occupy the more polluted waters of the estuary only seasonally, and this may account for their lower residue concentrations. 59 refs., 1 fig., 5 tabs.

The Effect of Live Spontaneous Harp Music on Patients in the Intensive Care Unit

Directory of Open Access Journals (Sweden)

Ann Marie Chiasson

2013-01-01

Full Text Available This study was performed to investigate the effect of live, spontaneous harp music on individual patients in an intensive care unit (ICU, either pre- or postoperatively. The purpose was to determine whether this intervention would serve as a relaxation or healing modality, as evidenced by the effect on patient’s pain, heart rate, respiratory rate, blood pressure, oxygen saturation, and heart rate variability. Each consenting patient was randomly assigned to receive either a live 10-minute concert of spontaneous music played by an expert harpist or a 10-minute rest period. Spontaneous harp music significantly decreased patient perception of pain by 27% but did not significantly affect heart rate, respiratory rate, oxygen saturation, blood pressure, or heart rate variability. Trends emerged, although being not statistically significant, that systolic blood pressure increased while heart rate variability decreased. These findings may invoke patient engagement, as opposed to relaxation, as the underlying mechanism of the decrease in the patients’ pain and of the healing benefit that arises from the relationship between healer, healing modality, and patient.

Energy resolution studies of an IROC GEM prototype for the ALICE TPC

Energy Technology Data Exchange (ETDEWEB)

Mathis, Andreas [TU Muenchen, Physik Department E12, Excellence Cluster ' ' Universe' ' , D-85748, Garching (Germany); Collaboration: ALICE-Collaboration

2015-07-01

The ALICE collaboration (A Large Ion Collider Experiment) is planning an upgrade of its central barrel detectors, to be able to cope with the increased LHC luminosity beyond 2018. In order to fully exploit the increase in collision rate to about 50 kHz in Pb-Pb, the TPC is foreseen to be operated in an ungated mode with continuous readout. This demands for a replacement of the currently used, gated MWPC by GEM-based readout chambers, while retaining the present tracking and particle identification capabilities of the TPC via measurement of the specific energy loss (dE/dx). The present baseline solution for the TPC upgrade consists of a stack of four large-sized GEM foils as amplification stage, containing both Standard (S, 140 μm) and Large Pitch (LP, 280 μm) GEM foils arranged in the order S-LP-LP-S. This arrangement has been proven as advantageous in terms of ion backflow and energy resolution. A prototype of an ALICE IROC (Inner Readout Chamber) was equipped with such a quadruple GEM stack, installed inside a field cage and exposed to a beam of electrons and pions from the CERN PS. The performance of the prototype in terms of energy resolution has been evaluated and is presented.

Modular TPC's for relativistic heavy ion experiments

International Nuclear Information System (INIS)

Etkin, A.; Eiseman, S.E.; Foley, K.J.

1989-01-01

We have developed a TPC system for use in relativistic heavy ion experiments that permits the efficient reconstruction of high multiplicity events including events with decay vertices. It operates with the beam through the middle of the chamber giving good efficiency, two-track separation and spatial resolution. The three-dimensional points in this system allow the reconstruction of the complex events of interest. The use of specially developed hybrid electronics allows us to build a compact and cost-effective system. 11 figs

First results from the CERES radial TPC

CERN Document Server

AUTHOR|(CDS)2108583; Appelshäuser, H; Baur, R; Belaga, V; Bell, R; Braun-Munzinger, P; Ceretto, F; Cherlin, A; Damjanovic, S; Dietel, T; Drees, A; Ernst, P; Esumi, S I; Filimonov, K; Fraenkel, Zeev; Gnaenski, A; Garabatos, C; Glässel, P; Hanzal, V; Hausmann, M; Hering, G; Hrivnacova, I; Holl, P; Kushpil, V; Lenkeit, B C; Messer, M; Milov, A; Miskowiec, D; Panebratsev, Yu A; Petracek, V; Pfeiffer, A; Rak, J; Ravinovich, I; Razin, S; Rehak, P; Richter, M; Saveljic, N; Schäfer, E; Schmitz, W; Schükraft, Jürgen; Seipp, W; Sharma, A; Shimansky, S S; Slivova, J; Socol, E; Specht, H J; Stachel, J; Stiller, P; Sumbera, M; Tilsner, H; Tserruya, Itzhak; Voigt, C A; Voloshin, S A; Wessels, J P; Wienold, T; Windelband, B; Wurm, J P; Xie, W; Yurevich, V

1999-01-01

The CERES/NA45 experiment at the CERN SPS was upgraded in 1998 by the addition of a cylindrical Time Projection Chamber. The aim is to improve the mass resolution of e sup + e sup - pairs in the rho/omega/phi region to DELTA m/m < 2%. A progress report is given on the TPC performance during the 1998 commissioning runs (laser rays, beam halo muons, and particles produced by proton/pi and lead beams hitting Pb and Au targets).

First results from the CERES radial TPC

Energy Technology Data Exchange (ETDEWEB)

Marin, A.; Agakichiev, G.; Appelshaeuser, H.; Baur, R.; Belaga, V.; Bell, R.; Braun-Munzinger, P.; Ceretto, F.; Cherlin, A.; Damjanovic, S.; Dietel, T.; Drees, A.; Ernst, P.; Esumi, S.I.; Filimonov, K.; Fraenkel, Z.; Gnaenski, A.; Garabatos, C.; Glaessel, P.; Hanzal, V.; Hausmann, M.; Hering, G.; Hrivnacova, I.; Holl, P.; Kushpil, V.; Lenkeit, B.; Messer, M.; Milov, A.; Miskowiec, D.; Panebrattsev, Y.; Petracek, V.; Pfeiffer, A.; Rak, J.; Ravinovich, I.; Razin, S.; Rehak, P.; Richter, M.; Saveljic, N.; Schaefer, E.; Schmitz, W.; Schukraft, J.; Seipp, W.; Sharma, A.; Shimansky, S.; Slivova, J.; Socol, E.; Specht, H.J.; Stachel, J.; Stiller, P.; Sumbera, M.; Tilsner, H.; Tserruya, I.; Voigt, C.; Voloshin, S.; Wessels, J.P.; Wienold, T.; Windelband, B.; Wurm, J.P.; Xie, W.; Yurevich, V

1999-12-27

The CERES/NA45 experiment at the CERN SPS was upgraded in 1998 by the addition of a cylindrical Time Projection Chamber. The aim is to improve the mass resolution of e{sup +}e{sup -} pairs in the {rho}/{omega}/phi region to {delta}m/m < 2%. A progress report is given on the TPC performance during the 1998 commissioning runs (laser rays, beam halo muons, and particles produced by proton/{pi} and lead beams hitting Pb and Au targets)

First measurement of dE/dx with a GEM-based TPC

International Nuclear Information System (INIS)

Böhmer, F.V.; Ball, M.; Dørheim, S.; Eckstein, K.; Hönle, A.; Höppner, C.; Ketzer, B.; Konorov, I.; Neubert, S.; Paul, S.; Rauch, J.; Uhl, S.; Vandenbroucke, M.; Berger, M.; Berger-Chen, J.-C.; Cusanno, F.; Fabbietti, L.; Gasik, P.; Münzer, R.; Arora, R.

2014-01-01

In this work we present the first measurement of the specific energy loss (dE/dx) and an analysis of the resulting charged-particle identification (PID) capabilities of a large-scale TPC with GEM-based gas amplification. The data has been recorded inside the FOPI spectrometer at GSI, Germany, using reactions of 1.7 GeV/c pions impinging on a carbon target. In the specific energy loss spectrum clear bands for pions, kaons, protons and deuterons are observed. The specific energy loss resolution is studied as a function of the total particle momentum and as a function of the track length. It is found to be ∼15%, consistent with expectations

First measurement of dE/dx with a GEM-based TPC

Energy Technology Data Exchange (ETDEWEB)

Böhmer, F.V., E-mail: felix.boehmer@tum.de [Technische Universität München, Physik Department E18, D-85748 Garching (Germany); Ball, M.; Dørheim, S.; Eckstein, K.; Hönle, A.; Höppner, C.; Ketzer, B.; Konorov, I.; Neubert, S.; Paul, S.; Rauch, J.; Uhl, S.; Vandenbroucke, M. [Technische Universität München, Physik Department E18, D-85748 Garching (Germany); Berger, M.; Berger-Chen, J.-C.; Cusanno, F.; Fabbietti, L.; Gasik, P.; Münzer, R. [Excellence Cluster Universe, Technische Universität München, D-85748 Garching (Germany); Arora, R. [GSI Helmholtzzentrum für Schwerionenforschung GmbH, D-64291 Darmstadt (Germany); and others

2014-02-11

In this work we present the first measurement of the specific energy loss (dE/dx) and an analysis of the resulting charged-particle identification (PID) capabilities of a large-scale TPC with GEM-based gas amplification. The data has been recorded inside the FOPI spectrometer at GSI, Germany, using reactions of 1.7 GeV/c pions impinging on a carbon target. In the specific energy loss spectrum clear bands for pions, kaons, protons and deuterons are observed. The specific energy loss resolution is studied as a function of the total particle momentum and as a function of the track length. It is found to be ∼15%, consistent with expectations.

ARIADNE, a Photographic LAr TPC at the CERN Neutrino Platform

CERN Document Server

Mavrokoridis, K; Nessi, M; Roberts, A; Smith, N A; Touramanis, C; CERN. Geneva. SPS and PS Experiments Committee; SPSC

2016-01-01

This letter of intent describes a novel and innovative two-phase LAr TPC with photographic capabilities as an attractive alternative readout method to the currently accepted segmented THGEMs which will require many thousands of charge readout channels for kton-scale two-phase TPCs. These colossal LAr TPCs will be used for the future long-baseline-neutrino-oscillation experiments. Optical readout also presents many other clear advantages over current readout techniques such as ease of scalability, upgrade, installation and maintenance, and cost effectiveness. This technology has already been demonstrated at the Liverpool LAr facility with the photographic capturing of cosmic muon tracks and single gammas using a 40-litre prototype. We have now secured ERC funding to develop this further with the ARIADNE programme. ARIADNE will be a 1-ton two-phase LAr TPC utilizing THGEM and EMCCD camera readouts in order to photograph interactions, allowing for track reconstruction and particle identification. We are request...

Measuring Cross-Section and Estimating Uncertainties with the fissionTPC

Energy Technology Data Exchange (ETDEWEB)

Bowden, N. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Manning, B. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Sangiorgio, S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Seilhan, B. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

2015-01-30

The purpose of this document is to outline the prescription for measuring fission cross-sections with the NIFFTE fissionTPC and estimating the associated uncertainties. As such it will serve as a work planning guide for NIFFTE collaboration members and facilitate clear communication of the procedures used to the broader community.

The HARPS-N Rocky Planet Search

DEFF Research Database (Denmark)

Motalebi, F.; Udry, S.; Gillon, M.

2015-01-01

We know now from radial velocity surveys and transit space missions that planets only a few times more massive than our Earth are frequent around solar-type stars. Fundamental questions about their formation history, physical properties, internal structure, and atmosphere composition are, however......, still to be solved. We present here the detection of a system of four low-mass planets around the bright (V = 5.5) and close-by (6.5 pc) star HD 219134. This is the first result of the Rocky Planet Search programme with HARPS-N on the Telescopio Nazionale Galileo in La Palma. The inner planet orbits...... on a close-in, quasi-circular orbit with a period of 6.767 ± 0.004 days. The third planet in the system has a period of 46.66 ± 0.08 days and a minimum-mass of 8.94 ± 1.13 M⊕, at 0.233 ± 0.002 AU from the star. Its eccentricity is 0.46 ± 0.11. The period of this planet is close to the rotational period...

Performance of an optical readout GEM-based TPC

International Nuclear Information System (INIS)

Margato, L.M.S.; Fraga, F.A.F.; Fetal, S.T.G.; Fraga, M.M.F.R.; Balau, E.F.S.; Blanco, A.; Marques, R. Ferreira; Policarpo, A.J.P.L

2004-01-01

We report on the operation of a GEM-based small TPC using an optical readout. The detector was operated with a mixture of Ar+CF 4 using 5.48 MeV alpha particles obtained from a 241 Am source and the GEM scintillation was concurrently read by a CCD camera and a photomultiplier. Precision collimators were used to define the track orientation. Qualitative results on the accuracy of the track angle, length and charge deposition measurements are presented

HADES RV programme with HARPS-N at TNG. VII. Rotation and activity of M-dwarfs from time-series high-resolution spectroscopy of chromospheric indicators

Science.gov (United States)

Mascareño, A. Suárez; Rebolo, R.; González Hernández, J. I.; Toledo-Padrón, B.; Perger, M.; Ribas, I.; Affer, L.; Micela, G.; Damasso, M.; Maldonado, J.; González-Alvarez, E.; Leto, G.; Pagano, I.; Scandariato, G.; Sozzetti, A.; Lanza, A. F.; Malavolta, L.; Claudi, R.; Cosentino, R.; Desidera, S.; Giacobbe, P.; Maggio, A.; Rainer, M.; Esposito, M.; Benatti, S.; Pedani, M.; Morales, J. C.; Herrero, E.; Lafarga, M.; Rosich, A.; Pinamonti, M.

2018-05-01

We aim to investigate the presence of signatures of magnetic cycles and rotation on a sample of 71 early M-dwarfs from the HADES RV programme using high-resolution time-series spectroscopy of the Ca II H&K and Hα chromospheric activity indicators, the radial velocity series, the parameters of the cross correlation function and the V -band photometry. We used mainly HARPS-N spectra, acquired over 4 yr, and add HARPS spectra from the public ESO database and ASAS photometry light-curves as support data, extending the baseline of the observations of some stars up to 12 yr. We provide log10(R'HK) measurements for all the stars in the sample, cycle length measurements for 13 stars, rotation periods for 33 stars and we are able to measure the semi-amplitude of the radial velocity signal induced by rotation in 16 stars. We complement our work with previous results and confirm and refine the previously reported relationships between the mean level of chromospheric emission, measured by the log10(R'HK), with the rotation period, and with the measured semi-amplitude of the activity induced radial velocity signal for early M-dwarfs. We searched for a possible relation between the measured rotation periods and the lengths of the magnetic cycle, finding a weak correlation between both quantities. Using previous v sin i measurements we estimated the inclinations of the star's poles to the line of sight for all the stars in the sample, and estimate the range of masses of the planets GJ 3998 b and c (2.5-4.9 and 6.3-12.5 M⊕), GJ 625 b (2.82 M⊕), GJ 3942 b (7.1-10.0 M⊕) and GJ 15A b (3.1-3.3 M⊕), assuming their orbits are coplanar with the stellar rotation. Based on: observations made with the Italian Telescopio Nazionale Galileo (TNG), operated on the island of La Palma by the INAF - Fundación Galileo Galilei at the Roche de Los Muchachos Observatory of the Instituto de Astrofísica de Canarias (IAC); observations made with the HARPS instrument on the ESO 3.6-m telescope

arXiv Status of the R&D activities for the upgrade of the ALICE TPC

CERN Document Server

Deisting, Alexander

2018-01-01

In order to cope with the high interaction rates provided by the LHC after the long shut-down 2, the ALICE TPC needs to be upgraded. After the upgrade the TPC will run in a continuous mode, without any degradation of the momentum and $\\textrm{d}E/\\textrm{d}x$ resolution compared to the performance of the present TPC. Since readout by MWPCs is no longer feasible with these requirements, new technologies have to be employed. In the new readout the electron amplification is provided by a stack of four GEM foils. Here foils with a standard hole pitch of 140um as well as large pitch foils (280um) are used. Their high voltage settings and orientation have been optimised to provide an energy resolution of $\\sigma_{{E}}/{E}\\leq12\\%$ at the photopeak of $^{55}\\textrm{Fe}$. At the same settings the Ion BackFlow into the drift volume is less than 1% of the effective number of ions produced during gas amplification and the primary ionisations. This is necessary to prevent the accumulation of space charge, which eventuall...

The ALICE TPC, a high resolution device for ultra-high particle multiplicities. Past, present and future

Energy Technology Data Exchange (ETDEWEB)

Ivanov, Marian [GSI Helmholtzzentrum fuer Schwerionenforschung GmbH (Germany); Collaboration: ALICE-Collaboration

2015-07-01

The Time Projection Chamber (TPC) of the ALICE apparatus is a large 3-dimensional tracking and particle identification device for ultra-high multiplicity collision events. It has been operated successfully at the Large Hadron Collider (LHC) at CERN, recording data from pp, p-Pb, and Pb-Pb collisions. Presently, LHC is in its first long shutdown (LS1), the next round of data taking will start in summer 2015 at or close to the LHC design energy and luminosity. During the second long shutdown (LS2), LHC will undergo a further increase in the Pb-Pb luminosity together with a major upgrade of ALICE. After the upgrade, the ALICE TPC will operate with Pb-Pb collisions at an interaction rate of 50 kHz. We present the performance in operation, calibration and reconstruction with the ALICE TPC together with ongoing work and plans for the near future and the coming 10 years.

Live event reconstruction in an optically read out GEM-based TPC

Science.gov (United States)

Brunbauer, F. M.; Galgóczi, G.; Gonzalez Diaz, D.; Oliveri, E.; Resnati, F.; Ropelewski, L.; Streli, C.; Thuiner, P.; van Stenis, M.

2018-04-01

Combining strong signal amplification made possible by Gaseous Electron Multipliers (GEMs) with the high spatial resolution provided by optical readout, highly performing radiation detectors can be realized. An optically read out GEM-based Time Projection Chamber (TPC) is presented. The device permits 3D track reconstruction by combining the 2D projections obtained with a CCD camera with timing information from a photomultiplier tube. Owing to the intuitive 2D representation of the tracks in the images and to automated control, data acquisition and event reconstruction algorithms, the optically read out TPC permits live display of reconstructed tracks in three dimensions. An Ar/CF4 (80/20%) gas mixture was used to maximize scintillation yield in the visible wavelength region matching the quantum efficiency of the camera. The device is integrated in a UHV-grade vessel allowing for precise control of the gas composition and purity. Long term studies in sealed mode operation revealed a minor decrease in the scintillation light intensity.

Development of the GEM-TPC X-ray Polarimeter with the Scalable Readout System

Directory of Open Access Journals (Sweden)

Kitaguchi Takao

2018-01-01

Full Text Available We have developed a gaseous Time Projection Chamber (TPC containing a single-layered foil of a gas electron multiplier (GEM to open up a new window on cosmic X-ray polarimetry in the 2–10 keV band. The micro-pattern TPC polarimeter in combination with the Scalable Readout System produced by the RD51 collaboration has been built as an engineering model to optimize detector parameters and improve polarimeter sensitivity. The polarimeter was characterized with unpolarized X-rays from an X-ray generator in a laboratory and polarized X-rays on the BL32B2 beamline at the SPring-8 synchrotron radiation facility. Preliminary results show that the polarimeter has a comparable modulation factor to a prototype of the flight one.

Methods and results for calibration and track separation of a GEM based TPC using an UV-laser

International Nuclear Information System (INIS)

Ball, Markus

2008-12-01

In the last 30 years high energy physics could write an impressive story of success. Since the introduction of the Standard Model (SM), it has met every experimental test. However the final confirmation has to prove the mechanism of electroweak symmetry breaking, which could not be confirmed yet. The most favored theory, which includes the introduction of a Higgs field, could not be verified experimentally. Furthermore there is clear evidence, that the SM is only a low energy description of nature and its principles, as the SM describes only 4 % of the known matter in the universe. There are two different approaches in accelerator driven high energy physics to clarify the open questions. The Large Hadron Collider (LHC) have a good opportunity to measure some of the missing pieces with its high center of mass energy. The International Linear Collider (ILC) will then measure their parameters with high precision. To guarantee this high precision the detectors have to be able to identify every single particle and determine its properties with high accuracy. These high requirements to the single detectors as well as the interconnectivity between all detectors are summarised by the concept of particle flow (PFLOW). This means that all particles must be separable, which includes in particular the main tracking device. A possible candidate for the central tracking device is a Time Projection Chamber (TPC). In this work a TPC with Gas Electron Multipliers (GEM) as gas amplification system was used. The GEMs replace the conventional wire amplification system of the TPC. In this PhD work a method to determine the drift velocity of a TPC was developed and tested using an ultraviolet laser. To ensure a high accuracy of the method all relevant gas parameters were measured with a slow control system. Furthermore the laser was used to investigate the separation capability of nearby tracks. Therefore an existing TPC prototype, which was developed to operate in a 5 T magnet facility

Methods and results for calibration and track separation of a GEM based TPC using an UV-laser

Energy Technology Data Exchange (ETDEWEB)

Ball, Markus

2008-12-15

In the last 30 years high energy physics could write an impressive story of success. Since the introduction of the Standard Model (SM), it has met every experimental test. However the final confirmation has to prove the mechanism of electroweak symmetry breaking, which could not be confirmed yet. The most favored theory, which includes the introduction of a Higgs field, could not be verified experimentally. Furthermore there is clear evidence, that the SM is only a low energy description of nature and its principles, as the SM describes only 4 % of the known matter in the universe. There are two different approaches in accelerator driven high energy physics to clarify the open questions. The Large Hadron Collider (LHC) have a good opportunity to measure some of the missing pieces with its high center of mass energy. The International Linear Collider (ILC) will then measure their parameters with high precision. To guarantee this high precision the detectors have to be able to identify every single particle and determine its properties with high accuracy. These high requirements to the single detectors as well as the interconnectivity between all detectors are summarised by the concept of particle flow (PFLOW). This means that all particles must be separable, which includes in particular the main tracking device. A possible candidate for the central tracking device is a Time Projection Chamber (TPC). In this work a TPC with Gas Electron Multipliers (GEM) as gas amplification system was used. The GEMs replace the conventional wire amplification system of the TPC. In this PhD work a method to determine the drift velocity of a TPC was developed and tested using an ultraviolet laser. To ensure a high accuracy of the method all relevant gas parameters were measured with a slow control system. Furthermore the laser was used to investigate the separation capability of nearby tracks. Therefore an existing TPC prototype, which was developed to operate in a 5 T magnet facility

Readout and trigger electronics for the TPC vertex chamber

International Nuclear Information System (INIS)

Ronan, M.T.; Jared, R.C.; McGathen, T.K.; Eisner, A.M.; Broeder, W.J.; Godfrey, G.L.

1987-10-01

The introduction of the vertex chamber required the addition of new front-end electronics and a new 1024-channel, high-accuracy TDC system. The preamplifier/discriminator should be capable of triggering on the first electrons and the time digitzer should preserve the measurement resolution. For the TDC's, in order to maintain compatibility with the existing TPC readout system, an upgrade of a previous inner drift chamber digitizer system has been chosen. Tests of the accuracy and stability of the original design indicated that the new design specifications would be met. The TPC detector requires a fast pretrigger to turn on its gating grid within 500 ns of the e/sup +/e/sup -/ beam crossing time, to minimize the loss of ionization information. A pretrigger based on the Straw Chamber signals, operating at a rate of about 2 K/sec, will be used for charged particle final states. In addition, in order to reject low mass Two-Photon events at the final trigger level, an accurate transverse momentum cutoff will be made by the Straw Chamber trigger logic. In this paper, we describe the readout and trigger electronics systems which have been built to satisfy the above requirements. 5 refs., 8 figs

TPC2 polymorphisms associated with a hair pigmentation phenotype in humans result in gain of channel function by independent mechanisms.

Science.gov (United States)

Chao, Yu-Kai; Schludi, Verena; Chen, Cheng-Chang; Butz, Elisabeth; Nguyen, O N Phuong; Müller, Martin; Krüger, Jens; Kammerbauer, Claudia; Ben-Johny, Manu; Vollmar, Angelika M; Berking, Carola; Biel, Martin; Wahl-Schott, Christian A; Grimm, Christian

2017-10-10

Two-pore channels (TPCs) are endolysosomal cation channels. Two members exist in humans, TPC1 and TPC2. Functional roles associated with the ubiquitously expressed TPCs include VEGF-induced neoangiogenesis, LDL-cholesterol trafficking and degradation, physical endurance under fasting conditions, autophagy regulation, the acrosome reaction in sperm, cancer cell migration, and intracellular trafficking of pathogens such as Ebola virus or bacterial toxins (e.g., cholera toxin). In a genome-wide association study for variants associated with human pigmentation characteristics two coding variants of TPC2, rs35264875 (encoding M484L) and rs3829241 (encoding G734E), have been found to be associated with a shift from brown to blond hair color. In two recent follow-up studies a role for TPC2 in pigmentation has been further confirmed. However, these human polymorphic variants have not been functionally characterized until now. The development of endolysosomal patch-clamp techniques has made it possible to investigate directly ion channel activities and characteristics in isolated endolysosomal organelles. We applied this technique here to scrutinize channel characteristics of the polymorphic TPC2 variants in direct comparison with WT. We found that both polymorphisms lead to a gain of channel function by independent mechanisms. We next conducted a clinical study with more than 100 blond- and brown/black-haired individuals. We performed a genotype/phenotype analysis and subsequently isolated fibroblasts from WT and polymorphic variant carriers for endolysosomal patch-clamp experimentation to confirm key in vitro findings.

Gating of the two-pore cation channel AtTPC1 in the plant vacuole is based on a single voltage-sensing domain.

Science.gov (United States)

Jaślan, D; Mueller, T D; Becker, D; Schultz, J; Cuin, T A; Marten, I; Dreyer, I; Schönknecht, G; Hedrich, R

2016-09-01

The two-pore cation channel TPC1 operates as a dimeric channel in animal and plant endomembranes. Each subunit consists of two homologous Shaker-like halves, with 12 transmembrane domains in total (S1-S6, S7-S12). In plants, TPC1 channels reside in the vacuolar membrane, and upon voltage stimulation, give rise to the well-known slow-activating SV currents. Here, we combined bioinformatics, structure modelling, site-directed mutagenesis, and in planta patch clamp studies to elucidate the molecular mechanisms of voltage-dependent channel gating in TPC1 in its native plant background. Structure-function analysis of the Arabidopsis TPC1 channel in planta confirmed that helix S10 operates as the major voltage-sensing site, with Glu450 and Glu478 identified as possible ion-pair partners for voltage-sensing Arg537. The contribution of helix S4 to voltage sensing was found to be negligible. Several conserved negative residues on the luminal site contribute to calcium binding, stabilizing the closed channel. During evolution of plant TPC1s from two separate Shaker-like domains, the voltage-sensing function in the N-terminal Shaker-unit (S1-S4) vanished. © 2016 German Botanical Society and The Royal Botanical Society of the Netherlands.

Food consumption estimates of Barents Sea harp seals

Directory of Open Access Journals (Sweden)

Kjell T Nilssen

2004-05-01

total consumption, other gadoids (dominated by cod, but also including haddock (Melanogrammus aeglefinus and saithe (Pollachius virens, herring, and "other fish". Using the same set of assumptions as in the previous estimate, the total consumption would have been 3.47 million tonnes, divided between various prey species as follows (in tonnes: polar cod 876,000, codfish (cod, saithe and haddock 359,700, "other fish" 618,800, herring 392,500, and crustaceans 1,204,200. Overall, the largest quantities of food were estimated to be consumed in the period June-September. In 1999, the total Barents Sea harp seal stock size was estimated to be 2.18 (95% CI, 1.79 to 2.58 million animals, which would give an annual food consumption in the range of 2,69 - 3.96 million tonnes (based on upper and lower 95% confidence limits and adjusted for a pup mortality rate of 0.3 if capelin is assumed to be abundant.

The Kepler-10 planetary system revisited by HARPS-N: A hot rocky world and a solid Neptune-mass planet

Energy Technology Data Exchange (ETDEWEB)

Dumusque, Xavier; Buchhave, Lars A.; Latham, David W.; Charbonneau, David; Dressing, Courtney D.; Gettel, Sara; Lopez-Morales, Mercedes [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Bonomo, Aldo S. [INAF - Osservatorio Astrofisico di Torino, via Osservatorio 20, I-10025 Pino Torinese (Italy); Haywood, Raphaëlle D.; Cameron, Andrew Collier; Horne, Keith [SUPA, School of Physics and Astronomy, University of St. Andrews, North Haugh, St. Andrews Fife KY16 9SS (United Kingdom); Malavolta, Luca [Dipartimento di Fisica e Astronomia " Galileo Galilei," Universita' di Padova, Vicolo dell' Osservatorio 3, I-35122 Padova (Italy); Ségransan, Damien; Pepe, Francesco; Udry, Stéphane [Observatoire Astronomique de l' Université de Genève, 51 ch. des Maillettes, CH-1290 Versoix (Switzerland); Molinari, Emilio; Cosentino, Rosario; Fiorenzano, Aldo F. M.; Harutyunyan, Avet [INAF - Fundacin Galileo Galilei, Rambla Jos Ana Fernandez Prez 7, E-38712 Brea Baja (Spain); Figueira, Pedro, E-mail: xdumusque@cfa.harvard.edu [Centro de Astrofìsica, Universidade do Porto, Rua das Estrelas, 4150-762 Porto (Portugal); and others

2014-07-10

Kepler-10b was the first rocky planet detected by the Kepler satellite and confirmed with radial velocity follow-up observations from Keck-HIRES. The mass of the planet was measured with a precision of around 30%, which was insufficient to constrain models of its internal structure and composition in detail. In addition to Kepler-10b, a second planet transiting the same star with a period of 45 days was statistically validated, but the radial velocities were only good enough to set an upper limit of 20 M{sub ⊕} for the mass of Kepler-10c. To improve the precision on the mass for planet b, the HARPS-N Collaboration decided to observe Kepler-10 intensively with the HARPS-N spectrograph on the Telescopio Nazionale Galileo on La Palma. In total, 148 high-quality radial-velocity measurements were obtained over two observing seasons. These new data allow us to improve the precision of the mass determination for Kepler-10b to 15%. With a mass of 3.33 ± 0.49 M{sub ⊕} and an updated radius of 1.47{sub −0.02}{sup +0.03} R{sub ⊕}, Kepler-10b has a density of 5.8 ± 0.8 g cm{sup –3}, very close to the value predicted by models with the same internal structure and composition as the Earth. We were also able to determine a mass for the 45-day period planet Kepler-10c, with an even better precision of 11%. With a mass of 17.2 ± 1.9 M{sub ⊕} and radius of 2.35{sub −0.04}{sup +0.09} R{sub ⊕}, Kepler-10c has a density of 7.1 ± 1.0 g cm{sup –3}. Kepler-10c appears to be the first strong evidence of a class of more massive solid planets with longer orbital periods.

First considerations for a readout system for the ILD TPC with the Timepix3

Energy Technology Data Exchange (ETDEWEB)

Schiffer, Tobias [Universitaet Bonn (Germany); Collaboration: LCTPC-Deutschland-Collaboration

2016-07-01

For the planned International Linear Collider (ILC) two detectors are proposed. One of them, the International Large Detector (ILD) uses a Time Projektion Chamber (TPC) as the main tracking device. As a readout system for this TPC, pixel chips are one of the considered options. An integrated Micromegas stage is foreseen as gas amplification stage, which is built directly on top of the chip. Since first tests of a Pixel-TPC with 160 Timepix ASICs showed promising results, one is interested in developing a detector using the Timepix3 ASIC. It has several advantages, first of all its feature to measure ToT and a ToA at the same time and its significantly increased readout rate. For this purpose a readout system needs to be developed which fulfils the requirements of the Timpix3 ASIC and also has a high scalability. The main challenges are the high speed readout with a clock of up to 640 MHz and the reliability of the system. Also, the data driven as well as the frame-based readout of the Timepix3 needs to be considered for the implementation. The main goal is to provide a fast and parallel readout of several million channels. An overview and the status of the planning is given. Also, the development challenges are discussed.

Study of a multi-module Micromegas TPC prototype for tracking at the International Linear Collider

International Nuclear Information System (INIS)

Bhattacharya, Deb-Sankar

2017-01-01

around the boundaries of the Micromegas modules. Four Micromegas modules have been considered in the simulation, resembling the experimental setup. Tracks are allowed to point in different directions. Taking the primary track as reference, residuals are calculated. The field lines, diffusion of electrons in gas, nature of track distortion and the residuals are numerically calculated in presence and in absence of magnetic field. The vector-E * vector-B effect has been simulated as well. Simulated results follow the experimental observations. The field lines near the holes of the micro-mesh (of a Micromegas) take a funnel shape and help to drive the primary electrons through the holes into the amplification gap. Due to transverse diffusion, the avalanche may also extend outside the funnel. The ions have larger mass and are barely influenced by the diffusion. These also follow the field lines and finally get collected at the micro-mesh. A small fraction of ions, however comes back to the drift region. This phenomenon is referred to as the ion back flow and quantified by the fraction: IBF=Nb/Nt, where Nt is the average number of ions produced in the avalanche and Nb is the number ions flowing back to drift region. A significant amount of IBF leads to space charge build-up and electric field distortion in the TPC. I have measured IBF in a Micromegas with the same amplification gap (128 μm) and the pitch (63 μm) as used at the LPTPC anode plate. IBF is found to be intrinsically low in Micromegas. As the radioactive source (Fe55) at the SINP test bench has been placed above the drift plane of the drift chamber, a TPC-like behavior is incorporated by mounting a secondary mesh between the drift and the micro-mesh. A detailed simulation has been performed to understand the influence of applying electric field between the two drift meshes to improve accuracy of the measurement. My works have been focused on studying a Micromegas-based TPC that can be employed at the ILD for

Simulation of double beta decay in the ''SeXe'' TPC

Science.gov (United States)

Mauger, F.

2007-04-01

In 2004, the NEMO collaboration has started some preliminary studies for a next-generation double beta decay experiment: SuperNEMO. The possibility to use a large gaseous TPC has been investigated using simulation and extrapolation of former experiments. In this talk, I report on the reasons why such techniques have not been selected in 2004 and led the NEMO collaboration to reuse the techniques implemented within the NEMO3 detector.

Fast algorithm of track reconstruction for the Delphy TPC

International Nuclear Information System (INIS)

Maillard, J.

1984-01-01

We describe a simple geometrical method (polar inversion) to reconstruct tracks. When the magnetic field is constant in magnitude and direction. This method uses geometrical properties of the trajectories. In the case of the DELPHI apparatus, the track reconstruction is done using TPC informations. After explaining the algorithm, we give results on ''GEANT'' simulated events using the ''Lund'' generator. Today we get a computer time of the order of 1.2 milliseconds on a CDC 7600 and an efficiency of 98% [fr

Online Calibration of the TPC Drift Time in the ALICE High Level Trigger

Science.gov (United States)

Rohr, David; Krzewicki, Mikolaj; Zampolli, Chiara; Wiechula, Jens; Gorbunov, Sergey; Chauvin, Alex; Vorobyev, Ivan; Weber, Steffen; Schweda, Kai; Lindenstruth, Volker

2017-06-01

A Large Ion Collider Experiment (ALICE) is one of the four major experiments at the Large Hadron Collider (LHC) at CERN. The high level trigger (HLT) is a compute cluster, which reconstructs collisions as recorded by the ALICE detector in real-time. It employs a custom online data-transport framework to distribute data and workload among the compute nodes. ALICE employs subdetectors that are sensitive to environmental conditions such as pressure and temperature, e.g., the time projection chamber (TPC). A precise reconstruction of particle trajectories requires calibration of these detectors. Performing calibration in real time in the HLT improves the online reconstructions and renders certain offline calibration steps obsolete speeding up offline physics analysis. For LHC Run 3, starting in 2020 when data reduction will rely on reconstructed data, online calibration becomes a necessity. Reconstructed particle trajectories build the basis for the calibration making a fast online-tracking mandatory. The main detectors used for this purpose are the TPC and Inner Tracking System. Reconstructing the trajectories in the TPC is the most compute-intense step. We present several improvements to the ALICE HLT developed to facilitate online calibration. The main new development for online calibration is a wrapper that can run ALICE offline analysis and calibration tasks inside the HLT. In addition, we have added asynchronous processing capabilities to support long-running calibration tasks in the HLT framework, which runs event-synchronously otherwise. In order to improve the resiliency, an isolated process performs the asynchronous operations such that even a fatal error does not disturb data taking. We have complemented the original loop-free HLT chain with ZeroMQ data-transfer components. The ZeroMQ components facilitate a feedback loop that inserts the calibration result created at the end of the chain back into tracking components at the beginning of the chain, after a

Status of the R&D activities for the upgrade of the ALICE TPC

Science.gov (United States)

Deisting, Alexander

2018-02-01

After the Long Shutdown 2 (LS2) the LHC will provide lead-lead collisions at interaction rates as high as 50 kHz. In order to cope with such conditions the ALICE Time Projection Chamber (TPC) needs to be upgraded. After the upgrade the TPC will run in a continuous mode, without any degradation of the momentum and dE/dx resolution compared to the performance of the present TPC. Since readout by multi-wire proportional chambers is no longer feasible with these requirements, new technologies have to be employed. In the new readout chambers the electron amplification is provided by a stack of four Gas ElectronMultiplier (GEM) foils. Here foils with a standard hole pitch of 140 μm as well as large pitch foils (280 μm) are used. Their high voltage settings and orientation have been optimised to provide an energy resolution of σE/E ≤ 12% at the photopeak of 55Fe. At the same settings the Ion BackFlow into the drift volume is less than 1% of the effective number of ions produced during gas amplification and the primary ionisations. This is necessary to prevent the accumulation of space charge, which eventually will distort the field in the drift volume. To ensure stable operation at the high loads during LHC run 3 the chambers have to be robust against discharges, too. With the selected configuration in a quadruple GEMstack the discharge probability is kept at the level of 10-12 discharges per incoming hadron. An overview of the ALICE TPC upgrade activities will be given in these proceedings and the optimised settings foreseen for the GEM stacks of the future readout chambers are introduced. Furthermore the outcome of two beam time campaigns at SPS and PS (at CERN) in the end of 2014 is shown. At this campaigns the stability against discharges and the dE/dx performance of a full size readout chamber prototype was tested. In addition it is reported on charging-up studies of 4GEM stacks and on tests of electromagnetic sagging of large GEM foils.

Fast TPC Online Tracking on GPUs and Asynchronous Data Processing in the ALICE HLT to facilitate Online Calibration

International Nuclear Information System (INIS)

Rohr, David; Gorbunov, Sergey; Krzewicki, Mikolaj; Breitner, Timo; Kretz, Matthias; Lindenstruth, Volker

2015-01-01

ALICE (A Large Heavy Ion Experiment) is one of the four major experiments at the Large Hadron Collider (LHC) at CERN, which is today the most powerful particle accelerator worldwide. The High Level Trigger (HLT) is an online compute farm of about 200 nodes, which reconstructs events measured by the ALICE detector in real-time. The HLT uses a custom online data-transport framework to distribute data and workload among the compute nodes.ALICE employs several calibration-sensitive subdetectors, e.g. the TPC (Time Projection Chamber). For a precise reconstruction, the HLT has to perform the calibration online. Online- calibration can make certain Offline calibration steps obsolete and can thus speed up Offline analysis. Looking forward to ALICE Run III starting in 2020, online calibration becomes a necessity.The main detector used for track reconstruction is the TPC. Reconstructing the trajectories in the TPC is the most compute-intense step during event reconstruction. Therefore, a fast tracking implementation is of great importance. Reconstructed TPC tracks build the basis for the calibration making a fast online-tracking mandatory.We present several components developed for the ALICE High Level Trigger to perform fast event reconstruction and to provide features required for online calibration.As first topic, we present our TPC tracker, which employs GPUs to speed up the processing, and which bases on a Cellular Automaton and on the Kalman filter. Our TPC tracking algorithm has been successfully used in 2011 and 2012 in the lead-lead and the proton-lead runs. We have improved it to leverage features of newer GPUs and we have ported it to support OpenCL, CUDA, and CPUs with a single common source code. This makes us vendor independent.As second topic, we present framework extensions required for online calibration. The extensions, however, are generic and can be used for other purposes as well. We have extended the framework to support asynchronous compute chains

GEM detector performance with innovative micro-TPC readout in high magnetic field

Directory of Open Access Journals (Sweden)

Garzia I.

2018-01-01

Full Text Available Gas detector development is one of the pillars of the research in fundamental physics. Since several years, a new concept of detectors, called Micro Pattern Gas Detector (MPGD, allowed to overcome several problems related to other types of commonly used detectors, like drift chamber and micro strips detectors, reducing the rate of discharges and providing better radiation tolerance. Among the most used MPGDs are the Gas Electron Multipliers (GEMs. Invented by Sauli in 1997, nowadays GEMs have become an important reality for particle detectors in high energy physics. Commonly deployed as fast timing detectors and triggers, their fast response, high rate capability and high radiation hardness make them also suitable as tracking detectors. The readout scheme is one of the most important features in tracking technology. Analog readout based on the calculation of the center of gravity technique allows to overcome the limit imposed by digital pads, whose spatial resolution is limited by the pitch dimensions. However, the presence of high external magnetic fields can distort the electronic cloud and affect the performance. The development of the micro-TPC reconstruction method brings GEM detectors into a new prospective, improving significantly the spatial resolutionin presence of high magnetic fields. This innovative technique allows to reconstruct the 3-dimensional particle position, as Time Projection Chamber, but within a drift gap of a few millimeters. In these report, the charge centroid and micro-TPC methods are described in details. We discuss the results of several test beams performed with planar chambers in magnetic field. These results are one of the first developments of micro-TPC technique for GEM detectors, which allows to reach unprecedented performance in a high magnetic field of 1 T.

GEM detector performance with innovative micro-TPC readout in high magnetic field

Science.gov (United States)

Garzia, I.; Alexeev, M.; Amoroso, A.; Baldini Ferroli, R.; Bertani, M.; Bettoni, D.; Bianchi, F.; Calcaterra, A.; Canale, N.; Capodiferro, M.; Cassariti, V.; Cerioni, S.; Chai, J. Y.; Chiozzi, S.; Cibinetto, G.; Cossio, F.; Cotta Ramusino, A.; De Mori, F.; Destefanis, M.; Dong, J.; Evangelisti, F.; Evangelisti, F.; Farinelli, R.; Fava, L.; Felici, G.; Fioravanti, E.; Gatta, M.; Greco, M.; Lavezzi, L.; Leng, C. Y.; Li, H.; Maggiora, M.; Malaguti, R.; Marcello, S.; Melchiorri, M.; Mezzadri, G.; Mignone, M.; Morello, G.; Pacetti, S.; Patteri, P.; Pellegrino, J.; Pelosi, A.; Rivetti, A.; Rolo, M. D.; Savrié, M.; Scodeggio, M.; Soldani, E.; Sosio, S.; Spataro, S.; Tskhadadze, E.; Verma, S.; Wheadon, R.; Yan, L.

2018-01-01

Gas detector development is one of the pillars of the research in fundamental physics. Since several years, a new concept of detectors, called Micro Pattern Gas Detector (MPGD), allowed to overcome several problems related to other types of commonly used detectors, like drift chamber and micro strips detectors, reducing the rate of discharges and providing better radiation tolerance. Among the most used MPGDs are the Gas Electron Multipliers (GEMs). Invented by Sauli in 1997, nowadays GEMs have become an important reality for particle detectors in high energy physics. Commonly deployed as fast timing detectors and triggers, their fast response, high rate capability and high radiation hardness make them also suitable as tracking detectors. The readout scheme is one of the most important features in tracking technology. Analog readout based on the calculation of the center of gravity technique allows to overcome the limit imposed by digital pads, whose spatial resolution is limited by the pitch dimensions. However, the presence of high external magnetic fields can distort the electronic cloud and affect the performance. The development of the micro-TPC reconstruction method brings GEM detectors into a new prospective, improving significantly the spatial resolutionin presence of high magnetic fields. This innovative technique allows to reconstruct the 3-dimensional particle position, as Time Projection Chamber, but within a drift gap of a few millimeters. In these report, the charge centroid and micro-TPC methods are described in details. We discuss the results of several test beams performed with planar chambers in magnetic field. These results are one of the first developments of micro-TPC technique for GEM detectors, which allows to reach unprecedented performance in a high magnetic field of 1 T.

Study of electron recombination in liquid argon with the ICARUS TPC

International Nuclear Information System (INIS)

Amoruso, S.; Antonello, M.; Aprili, P.; Arneodo, F.; Badertscher, A.; Baiboussinov, B.; Baldo Ceolin, M.; Battistoni, G.; Bekman, B.; Benetti, P.; Bischofberger, M.; Borio di Tigliole, A.; Brunetti, R.; Bruzzese, R.; Bueno, A.; Buzzanca, M.; Calligarich, E.; Campanelli, M.; Carbonara, F.; Carpanese, C.; Cavalli, D.; Cavanna, F.; Cennini, P.; Centro, S.; Cesana, A.; Chen, C.; Chen, D.; Chen, D.B.; Chen, Y.; Cieslik, K.; Cline, D.; Cocco, A.G.; Dai, Z.; De Vecchi, C.; Dabrowska, A.; Di Cicco, A.; Dolfini, R.; Ereditato, A.; Felcini, M.; Ferrari, A.; Ferri, F.; Fiorillo, G.; Galli, S.; Ge, Y.; Gibin, D.; Gigli Berzolari, A.; Gil-Botella, I.; Graczyk, K.; Grandi, L.; Guglielmi, A.; He, K.; Holeczek, J.; Huang, X.; Juszczak, C.; Kielczewska, D.; Kisiel, J.; Kozlowski, T.; Laffranchi, M.; Lagoda, J.; Li, Z.; Lu, F.; Ma, J.; Mangano, G.; Markiewicz, M.; Martinez de la Ossa, A.; Matthey, C.; Mauri, F.; Meng, G.; Messina, M.; Montanari, C.; Muraro, S.; Navas-Concha, S.; Otwinowski, S.; Ouyang, Q.; Palamara, O.; Pascoli, D.; Periale, L.; Piano Mortari, G.B.; Piazzoli, A.; Picchi, P.; Pietropaolo, F.; Polopek, W.; Rancati, T.; Rappoldi, A.; Raselli, G.L.; Rico, J.; Rondio, E.; Rossella, M.; Rubbia, A.; Rubbia, C.; Sala, P.R.; Santorelli, R.; Scannicchio, D.; Segreto, E.; Seo, Y.; Sergiampietri, F.; Sobczyk, J.; Spinelli, N.; Stepaniak, J.; Sulej, R.; Szarska, M.; Szeptycka, M.; Terrani, M.; Velotta, R.; Ventura, S.; Vignoli, C.; Wang, H.; Wang, X.; Woo, J.; Xu, G.; Xu, Z.; Zalewska, A.; Zhang, C.; Zhang, Q.; Zhen, S.; Zipper, W.

2004-01-01

Electron recombination in liquid argon (LAr) is studied by means of charged particle tracks collected in various ICARUS liquid argon TPC prototypes. The dependence of the recombination on the particle stopping power has been fitted with a Birks functional dependence. The simulation of the process of electron recombination in Monte Carlo calculations is discussed. A quantitative comparison with previously published data is carried out

R and D on a Fast LXe TPC with real-time event reconstruction

Energy Technology Data Exchange (ETDEWEB)

Dussoni, S., E-mail: simeone.dussoni@pi.infn.it [INFN Sezione di Pisa, Largo B. Pontecorvo 3, 56127 Pisa (Italy); Baldini, A. [INFN Sezione di Pisa, Largo B. Pontecorvo 3, 56127 Pisa (Italy); Galli, L. [INFN Sezione di Pisa, Largo B. Pontecorvo 3, 56127 Pisa (Italy); Paul Scherrer Institute PSI, CH-5232 Villigen (Switzerland); Cerri, C.; Grassi, M. [INFN Sezione di Pisa, Largo B. Pontecorvo 3, 56127 Pisa (Italy); Papa, A. [Paul Scherrer Institute PSI, CH-5232 Villigen (Switzerland); Signorelli, G. [INFN Sezione di Pisa, Largo B. Pontecorvo 3, 56127 Pisa (Italy)

2013-12-21

The FOXFIRE project (Feasibility Of a Xenon detector with Front-end for Ionization Real-time Extraction) aims at the realization of a Liquid Xenon TPC optimized for high rate particle physics experiments, in particular in the field of rare event searches, with particles in the 10–100 MeV energy range. Liquid Xenon has several attractive properties to be exploited resulting in superior time and energy resolution, by using the scintillation light readout with suitable photo-detectors. A novel approach with a complementary TPC readout scheme can improve the space resolution to a level of a few hundred microns. We are studying both the feasibility of a light readout with higher granularity by means of Silicon PhotoMultipliers optimized for the Xenon emission spectrum as well as on an innovative micro-fabricated device capable of charge multiplication in liquid phase. The detector will be equipped with a readout electronics capable of online reconstruction of events, allowing the detector to sustain a high rate of interactions.

Alpha-lipoic acid induces sodium iodide symporter expression in TPC-1 thyroid cancer cell line

International Nuclear Information System (INIS)

Choi, Hyun-Jeung; Kim, Tae Yong; Ruiz-Llorente, Sergio; Jeon, Min Ji; Han, Ji Min; Kim, Won Gu; Shong, Young Kee; Kim, Won Bae

2012-01-01

Introduction: Patients with metastatic thyroid cancers that do not uptake iodine need effective therapeutic option. Differentiation-inducing agents have been tried to restore functional expression of sodium iodide symporter (NIS) without success. Our objective was to assess the effect of alpha-lipoic acid (ALA), known as potential antioxidant, on expression of sodium iodide symporter in thyroid cancer cells. Methods: Human thyroid cancer-derived cell lines, TPC-1, were treated with ALA, and changes in NIS mRNA and protein expression were measured. ALA's effect on NIS gene promoter was evaluated, and functional NIS expression was assessed by iodide uptake assay. Results: Treatment with ALA increased NIS mRNA expression up to ten folds of control dose-dependently after 24 h of exposure. ALA increased NIS promoter activity, and increased iodide uptake by 1.6 fold. ALA induced expression of NIS protein, but had no significant effect on the plasma membrane trafficking. ALA increased phosphorylation of CREB and nuclear translocation of pCREB, and co-treatment of ALA and trichostatin A increased iodide uptake by three folds in TPC-1 cells. Conclusions: ALA is a potential agent to increase NIS transcription in TPC-1. It could be used as an adjunctive agent to increase efficacy of radioiodine therapy if combined with a strategy to increase NIS protein trafficking to cell membrane.

HARP targets pion production cross section and yield measurements. Implications for MiniBooNE neutrino flux

Energy Technology Data Exchange (ETDEWEB)

Wickremasinghe, Don Athula Abeyarathna [Univ. of Cincinnati, OH (United States)

2015-07-01

The prediction of the muon neutrino flux from a 71.0 cm long beryllium target for the MiniBooNE experiment is based on a measured pion production cross section which was taken from a short beryllium target (2.0 cm thick - 5% nuclear interaction length) in the Hadron Production (HARP) experiment at CERN. To verify the extrapolation to our longer target, HARP also measured the pion production from 20.0 cm and 40.0 cm beryllium targets. The measured production yields, d²N^π± (p; θ )=dpd Ω, on targets of 50% and 100% nuclear interaction lengths in the kinematic rage of momentum from 0.75 GeV/c to 6.5 GeV/c and the range of angle from 30 mrad to 210 mrad are presented along with an update of the short target cross sections. The best fitted extended Sanford-Wang (SW) model parameterization for updated short beryllium target π⁺ production cross section is presented. Yield measurements for all three targets are also compared with that from the Monte Carlo predictions in the MiniBooNE experiment for different SW parameterization. The comparisons of v_μ flux predictions for updated SW model is presented.

DarkSide-20k: A 20 Tonne Two-Phase LAr TPC for Direct Dark Matter Detection at LNGS

Energy Technology Data Exchange (ETDEWEB)

Aalseth, C.E.; et al.

2017-07-25

Building on the successful experience in operating the DarkSide-50 detector, the DarkSide Collaboration is going to construct DarkSide-20k, a direct WIMP search detector using a two-phase Liquid Argon Time Projection Chamber (LArTPC) with an active (fiducial) mass of 23 t (20 t). The DarkSide-20k LArTPC will be deployed within a shield/veto with a spherical Liquid Scintillator Veto (LSV) inside a cylindrical Water Cherenkov Veto (WCV). Operation of DarkSide-50 demonstrated a major reduction in the dominant $^{39}$Ar background when using argon extracted from an underground source, before applying pulse shape analysis. Data from DarkSide-50, in combination with MC simulation and analytical modeling, shows that a rejection factor for discrimination between electron and nuclear recoils of $\\gt3\\times10^9$ is achievable. This, along with the use of the veto system, is the key to unlocking the path to large LArTPC detector masses, while maintaining an "instrumental background-free" experiment, an experiment in which less than 0.1 events (other than $\

TPC2 is a novel NAADP-sensitive Ca2+ release channel, operating as a dual sensor of luminal pH and Ca2+.

Science.gov (United States)

Pitt, Samantha J; Funnell, Tim M; Sitsapesan, Mano; Venturi, Elisa; Rietdorf, Katja; Ruas, Margarida; Ganesan, A; Gosain, Rajendra; Churchill, Grant C; Zhu, Michael X; Parrington, John; Galione, Antony; Sitsapesan, Rebecca

2010-11-05

Nicotinic acid adenine dinucleotide phosphate (NAADP) is a molecule capable of initiating the release of intracellular Ca(2+) required for many essential cellular processes. Recent evidence links two-pore channels (TPCs) with NAADP-induced release of Ca(2+) from lysosome-like acidic organelles; however, there has been no direct demonstration that TPCs can act as NAADP-sensitive Ca(2+) release channels. Controversial evidence also proposes ryanodine receptors as the primary target of NAADP. We show that TPC2, the major lysosomal targeted isoform, is a cation channel with selectivity for Ca(2+) that will enable it to act as a Ca(2+) release channel in the cellular environment. NAADP opens TPC2 channels in a concentration-dependent manner, binding to high affinity activation and low affinity inhibition sites. At the core of this process is the luminal environment of the channel. The sensitivity of TPC2 to NAADP is steeply dependent on the luminal [Ca(2+)] allowing extremely low levels of NAADP to open the channel. In parallel, luminal pH controls NAADP affinity for TPC2 by switching from reversible activation of TPC2 at low pH to irreversible activation at neutral pH. Further evidence earmarking TPCs as the likely pathway for NAADP-induced intracellular Ca(2+) release is obtained from the use of Ned-19, the selective blocker of cellular NAADP-induced Ca(2+) release. Ned-19 antagonizes NAADP-activation of TPC2 in a non-competitive manner at 1 μM but potentiates NAADP activation at nanomolar concentrations. This single-channel study provides a long awaited molecular basis for the peculiar mechanistic features of NAADP signaling and a framework for understanding how NAADP can mediate key physiological events.

Performance of 20:1 multiplexer for large area charge readouts in directional dark matter TPC detectors

Science.gov (United States)

Ezeribe, A. C.; Robinson, M.; Robinson, N.; Scarff, A.; Spooner, N. J. C.; Yuriev, L.

2018-02-01

More target mass is required in current TPC based directional dark matter detectors for improved detector sensitivity. This can be achieved by scaling up the detector volumes, but this results in the need for more analogue signal channels. A possible solution to reducing the overall cost of the charge readout electronics is to multiplex the signal readout channels. Here, we present a multiplexer system in expanded mode based on LMH6574 chips produced by Texas Instruments, originally designed for video processing. The setup has a capability of reducing the number of readouts in such TPC detectors by a factor of 20. Results indicate that the important charge distribution asymmetry along an ionization track is retained after multiplexed signals are demultiplexed.

A 4π tracking TPC magnetic spectrometer for RHIC

International Nuclear Information System (INIS)

Danby, G.; Eiseman, S.E.; Etkin, A.; Foley, K.J.; Hackenburg, R.W.; Longacre, R.S.; Love, W.A.; Morris, T.W.; Platner, E.D.; Saulys, A.C.; Van Dijk, J.H.; Lindenbaum, S.J.; Chan, C.S.; Kramer, M.A.; Zhao, K.; Biswas, N.; Kenney, P.; Piekarz, J.; Adams, D.L.; Ahmad, S.; Bonner, B.E.; Buchanan, J.A.; Chiou, C.N.; Clement, J.M.; Corcoran, M.D.; Empl, T.; Miettinen, H.E.; Mutchler, G.S.; Roberts, J.B.; Skeens, J.

1990-01-01

The primary physics objective of the 4π TPC magnetic spectrometer proposal is to search for the Quark-Gluon Plasma. In previous workshops we have discussed what the possible hadronic signatures of such a state of matter would be. Succinctly, the QGP is a direct prediction of non-perturbative QCD. Therefore the question of the existence of this new state of matter bears directly on the validity of non-perturbative QCD. However, since non-perturbative QCD has never been established, it is apparent that what may await us is a host of new phenomena that will go beyond the standard model

Status of the R&D activities for the upgrade of the ALICE TPC

Directory of Open Access Journals (Sweden)

Deisting Alexander

2018-01-01

After the upgrade the TPC will run in a continuous mode, without any degradation of the momentum and dE/dx resolution compared to the performance of the present TPC. Since readout by multi-wire proportional chambers is no longer feasible with these requirements, new technologies have to be employed. In the new readout chambers the electron amplification is provided by a stack of four Gas ElectronMultiplier (GEM foils. Here foils with a standard hole pitch of 140 μm as well as large pitch foils (280 μm are used. Their high voltage settings and orientation have been optimised to provide an energy resolution of σE/E ≤ 12% at the photopeak of 55Fe. At the same settings the Ion BackFlow into the drift volume is less than 1% of the effective number of ions produced during gas amplification and the primary ionisations. This is necessary to prevent the accumulation of space charge, which eventually will distort the field in the drift volume. To ensure stable operation at the high loads during LHC run 3 the chambers have to be robust against discharges, too. With the selected configuration in a quadruple GEMstack the discharge probability is kept at the level of 10-12 discharges per incoming hadron. An overview of the ALICE TPC upgrade activities will be given in these proceedings and the optimised settings foreseen for the GEM stacks of the future readout chambers are introduced. Furthermore the outcome of two beam time campaigns at SPS and PS (at CERN in the end of 2014 is shown. At this campaigns the stability against discharges and the dE/dx performance of a full size readout chamber prototype was tested. In addition it is reported on charging-up studies of 4GEM stacks and on tests of electromagnetic sagging of large GEM foils.

The time-of-flight TOFW detector of the HARP experiment: construction and performance

International Nuclear Information System (INIS)

Baldo-Ceolin, M.; Barichello, G.; Bobisut, F.; Bonesini, M.; De Min, A.; Ferri, A.F.; Gibin, D.; Guglielmi, A.; Laveder, M.; Menegolli, A.; Mezzetto, M.; Paganoni, M.; Paleari, F.; Pepato, A.; Tonazzo, A.; Vascon, M.

2004-01-01

The construction and performance of a large area scintillator-based time-of-flight detector for the HARP experiment at CERN are reported. An intrinsic counter time resolution of ∼160 ps was achieved. The precision on the time calibration and monitoring of the detector was maintained at better than 100 ps by using dedicated cosmic rays runs, a fast laser-based system and calibrations with beam particles. The detector was operated on the T9 PS beamline during 2001 and 2002. A time-of-flight resolution of ∼200 ps was obtained, providing π/p discrimination at more than 3σ up to 4.0 GeV/c momentum

Identifying Charged Hadrons on the Relativistic Rise Using the ALICE TPC at LHC

CERN Document Server

Gros, Philippe

2011-01-01

The chain from hadron collisions to the physics results requires several important links. First the outcome of the collision is measured by the detectors. Then, the signal from the detector is processed and transformed into information relevant for the study of the physics processes. The data is made available to physicists to be analysed and used to improve theories. This thesis presents work done on no most of these steps for the ALICE experiment at LHC. First a study of the main processes in the TPC detector for ALICE was done using simulation and test beam data. The results are shown in paper I. The study was deepened with the analysis of test beam data from a TPC prototype for the ILC, as shown in paper III. Concurrently, a study on the Grid – computing framework for distributed computing and storage resources – was performed. This involved the development of an interface module between the ALICE software AliEn and the ARC software developped in the Nordic countries. This work is presented in paper I...

Characterization of UV-enhanced SiPMs for Imaging in High Pressure Xenon Electroluminescent TPC

International Nuclear Information System (INIS)

Yahlali, Nadia; Lorca, David; Fernandes, L.M.P.

2013-06-01

The possibility of recording charged particle tracks in an electro-luminescent xenon gas TPC is investigated using a SiPM-based tracking system, operated in the demonstrator prototype of the NEXT-100 ββ decay experiment. The tracks of the ββ0ν events from the decay of the 136 Xe isotope have a distinctive topology, which allows their discrimination against single-electron events from the natural radioactivity that populates the region of interest of the neutrinoless decay in the ββ energy spectrum. Combined to the near-intrinsic energy resolution of the gaseous detector, this tracking capability provides a powerful background rejection tool for the search of the neutrinoless ββ decay aimed by the experiment. The NEXT-100 detector concepts and sensitivity and the first results of its demonstrator prototype are presented. The characterization studies relevant for the operation of UV-enhanced SiPMs used for imaging in an electro-luminescent TPC are reviewed. (authors)

Hadron Production for the Neutrino Factory and for the Atmospheric Neutrino Flux

CERN Document Server

2002-01-01

The HARP experiment carries out, at the CERN PS, a programme of measurements of secondary hadron production, over the full solid angle, produced on thin and thick nuclear targets by beams of protons and pions with momenta in the range 2 to 15~\\GeVc. The first aim of this experiment is to acquire adequate knowledge of pion yields for an optimal design of the proton driver of the Neutrino Factory. The second aim is to reduce substantially the existing $\\sim 30$\\% uncertainty in the calculation of absolute atmospheric neutrino fluxes and the $\\sim 7$\\% uncertainty in the ratio of neutrino flavours, required for a refined interpretation of the evidence for neutrino oscillation from the study of atmospheric neutrinos in present and forthcoming experiments. The HARP experiment comprises a large-acceptance charged-particle magnetic spectrometer of conventional design, located in the East Hall of the CERN PS and using the T9 tagged charged-particle beam. The main detector is a cylindrical TPC inside a solenoid magnet...

A large area Micromegas TPC for tracking at the ILC

International Nuclear Information System (INIS)

Wang, Wenxin

2013-01-01

The study of the fundamental building blocks of matter necessitates always more powerful accelerators. New particles are produced in high energy collisions of protons or electrons. The by-Products of these collisions are detected in large apparatus surrounding the interaction point. The 125 GeV Higgs particle discovered at LHC will be studied in detail in the next e + e - collider. The leading project for this is called ILC. The team that I joined is working on the R and D for a Time Projection Chamber (TPC) to detect the charged tracks by the ionization they leave in a gas volume, optimised for use at ILC. This primary ionization is amplified by the so-Called Micromegas device, with a charge-Sharing anode made of a resistive-Capacitive coating. After a presentation of the physics motivation for the ILC and ILD detector, I will review the principle of operation of a TPC (Chapter 2) and underline the advantages of the Micromegas readout with charge sharing. The main part of this PhD work concerns the detailed study of up to 12 prototypes of various kinds. The modules and their readout electronics are described in Chapter 3. A test-Bench setup has been assembled at CERN (Chapter 4) to study the response to a 55 Fe source, allowing an energy calibration and a uniformity study. In Chapter 5, the ion back-flow is studied using a bulk Micromegas and the gas gain is measured using a calibrated electronics chain. With the same setup, the electron transparency is measured as a function of the field ratio (drift/amplification). Also, several beam tests have been carried out at DESY with a 5 GeV electron beam in a 1 T superconducting magnet. These beam tests allowed the detailed study of the spatial resolution. In the final test, the endplate was equipped with seven modules, bringing sensitivity to misalignment and distortions. Such a study required software developments (Chapter 6) to make optimal use of the charge sharing and to reconstruct multiple tracks through several

Amplification and scintillation properties of oxygen-rich gas mixtures for optical-TPC applications

International Nuclear Information System (INIS)

Weissman, L; Gai, M; Breskin, A; Chechik, R; Dangendorf, V; Tittelmeier, K; Weller, H R

2006-01-01

We studied electron amplification and light emission from avalanches in oxygen-containing gas mixtures. The mixtures investigated in this work included, among others, CO 2 and N 2 O mixed with Triethylamine (TEA) or N 2 . Double-Step Parallel Gap (DSPG) multipliers and THick Gas Electron Multipliers (THGEM) were investigated. High light yields were measured from CO 2 + N 2 and CO 2 + TEA, though with different emission spectra. We observed the characteristic wave-length emission of N 2 and of TEA and used a polymer wave-length shifter to convert TEA UV-light into the visible spectrum. The results of these measurements indicate the applicability of optical recording of ionizing tracks in a TPC target-detector designed to study the cross-sections of the 16 O(γ, α) 12 C reaction, a central problem in nuclear astrophysics

Asteroseismic observations and modelling of 70 Ophiuchi AB

Energy Technology Data Exchange (ETDEWEB)

Eggenberger, P; Miglio, A [Institut d' Astrophysique et de Geophysique de l' Universite de Liege, 17 Allee du 6 Aout, B-4000 Liege (Belgium); Carrier, F [Institute of Astronomy, University of Leuven, Celestijnenlaan 200 D, B-3001 Leuven (Belgium); Fernandes, J [Observatorio Astronomico da Universidade de Coimbra e Departamento de Matematica, FCTUC (Portugal); Santos, N C [Centro de AstrofIsica, Universidade do Porto, Rua das Estrelas, P-4150-762 Porto (Portugal)], E-mail: eggenberger@astro.ulg.ac.be

2008-10-15

The analysis of solar-like oscillations for stars belonging to a binary system provides an opportunity to probe the internal stellar structure and to test our knowledge of stellar physics. We present asteroseismic observations of 70 Oph A performed with the HARPS spectrograph together with a comprehensive theoretical calibration of the 70 Ophiuchi system.

Simulation of double beta decay in the 'SeXe' TPC

Energy Technology Data Exchange (ETDEWEB)

Mauger, F [LPC Caen and University of Caen, ENSICAEN, 6 Bd Marechal Juin, 14050 CAEN CEDEX 4 (France)

2007-04-15

In 2004, the NEMO collaboration has started some preliminary studies for a next-generation double beta decay experiment: SuperNEMO. The possibility to use a large gaseous TPC has been investigated using simulation and extrapolation of former experiments. In this talk, I report on the reasons why such techniques have not been selected in 2004 and led the NEMO collaboration to reuse the techniques implemented within the NEMO3 detector.

DarkSide-20k: A 20 tonne two-phase LAr TPC for direct dark matter detection at LNGS

Science.gov (United States)

Aalseth, C. E.; Acerbi, F.; Agnes, P.; Albuquerque, I. F. M.; Alexander, T.; Alici, A.; Alton, A. K.; Antonioli, P.; Arcelli, S.; Ardito, R.; Arnquist, I. J.; Asner, D. M.; Ave, M.; Back, H. O.; Barrado Olmedo, A. I.; Batignani, G.; Bertoldo, E.; Bettarini, S.; Bisogni, M. G.; Bocci, V.; Bondar, A.; Bonfini, G.; Bonivento, W.; Bossa, M.; Bottino, B.; Boulay, M.; Bunker, R.; Bussino, S.; Buzulutskov, A.; Cadeddu, M.; Cadoni, M.; Caminata, A.; Canci, N.; Candela, A.; Cantini, C.; Caravati, M.; Cariello, M.; Carlini, M.; Carpinelli, M.; Castellani, A.; Catalanotti, S.; Cataudella, V.; Cavalcante, P.; Cavuoti, S.; Cereseto, R.; Chepurnov, A.; Cicalò, C.; Cifarelli, L.; Citterio, M.; Cocco, A. G.; Colocci, M.; Corgiolu, S.; Covone, G.; Crivelli, P.; D'Antone, I.; D'Incecco, M.; D'Urso, D.; Da Rocha Rolo, M. D.; Daniel, M.; Davini, S.; de Candia, A.; De Cecco, S.; De Deo, M.; De Filippis, G.; De Guido, G.; De Rosa, G.; Dellacasa, G.; Della Valle, M.; Demontis, P.; Derbin, A.; Devoto, A.; Di Eusanio, F.; Di Pietro, G.; Dionisi, C.; Dolgov, A.; Dormia, I.; Dussoni, S.; Empl, A.; Fernandez Diaz, M.; Ferri, A.; Filip, C.; Fiorillo, G.; Fomenko, K.; Franco, D.; Froudakis, G. E.; Gabriele, F.; Gabrieli, A.; Galbiati, C.; Garcia Abia, P.; Gendotti, A.; Ghisi, A.; Giagu, S.; Giampa, P.; Gibertoni, G.; Giganti, C.; Giorgi, M. A.; Giovanetti, G. K.; Gligan, M. L.; Gola, A.; Gorchakov, O.; Goretti, A. M.; Granato, F.; Grassi, M.; Grate, J. W.; Grigoriev, G. Y.; Gromov, M.; Guan, M.; Guerra, M. B. B.; Guerzoni, M.; Gulino, M.; Haaland, R. K.; Hallin, A.; Harrop, B.; Hoppe, E. W.; Horikawa, S.; Hosseini, B.; Hughes, D.; Humble, P.; Hungerford, E. V.; Ianni, An.; Jillings, C.; Johnson, T. N.; Keeter, K.; Kendziora, C. L.; Kim, S.; Koh, G.; Korablev, D.; Korga, G.; Kubankin, A.; Kuss, M.; Kuźniak, M.; La Commara, M.; Lehnert, B.; Li, X.; Lissia, M.; Lodi, G. U.; Loer, B.; Longo, G.; Loverre, P.; Lussana, R.; Luzzi, L.; Ma, Y.; Machado, A. A.; Machulin, I. N.; Mandarano, A.; Mapelli, L.; Marcante, M.; Margotti, A.; Mari, S. M.; Mariani, M.; Maricic, J.; Martoff, C. J.; Mascia, M.; Mayer, M.; McDonald, A. B.; Messina, A.; Meyers, P. D.; Milincic, R.; Moggi, A.; Moioli, S.; Monroe, J.; Monte, A.; Morrocchi, M.; Mount, B. J.; Mu, W.; Muratova, V. N.; Murphy, S.; Musico, P.; Nania, R.; Navrer Agasson, A.; Nikulin, I.; Nosov, V.; Nozdrina, A. O.; Nurakhov, N. N.; Oleinik, A.; Oleynikov, V.; Orsini, M.; Ortica, F.; Pagani, L.; Pallavicini, M.; Palmas, S.; Pandola, L.; Pantic, E.; Paoloni, E.; Paternoster, G.; Pavletcov, V.; Pazzona, F.; Peeters, S.; Pelczar, K.; Pellegrini, L. A.; Pelliccia, N.; Perotti, F.; Perruzza, R.; Pesudo, V.; Piemonte, C.; Pilo, F.; Pocar, A.; Pollmann, T.; Portaluppi, D.; Pugachev, D. A.; Qian, H.; Radics, B.; Raffaelli, F.; Ragusa, F.; Razeti, M.; Razeto, A.; Regazzoni, V.; Regenfus, C.; Reinhold, B.; Renshaw, A. L.; Rescigno, M.; Retière, F.; Riffard, Q.; Rivetti, A.; Rizzardini, S.; Romani, A.; Romero, L.; Rossi, B.; Rossi, N.; Rubbia, A.; Sablone, D.; Salatino, P.; Samoylov, O.; Sánchez García, E.; Sands, W.; Sanfilippo, S.; Sant, M.; Santorelli, R.; Savarese, C.; Scapparone, E.; Schlitzer, B.; Scioli, G.; Segreto, E.; Seifert, A.; Semenov, D. A.; Shchagin, A.; Shekhtman, L.; Shemyakina, E.; Sheshukov, A.; Simeone, M.; Singh, P. N.; Skensved, P.; Skorokhvatov, M. D.; Smirnov, O.; Sobrero, G.; Sokolov, A.; Sotnikov, A.; Speziale, F.; Stainforth, R.; Stanford, C.; Suffritti, G. B.; Suvorov, Y.; Tartaglia, R.; Testera, G.; Tonazzo, A.; Tosi, A.; Trinchese, P.; Unzhakov, E. V.; Vacca, A.; Vázquez-Jáuregui, E.; Verducci, M.; Viant, T.; Villa, F.; Vishneva, A.; Vogelaar, B.; Wada, M.; Wahl, J.; Walding, J.; Wang, H.; Wang, Y.; Watson, A. W.; Westerdale, S.; Williams, R.; Wojcik, M. M.; Wu, S.; Xiang, X.; Xiao, X.; Yang, C.; Ye, Z.; Yllera de Llano, A.; Zappa, F.; Zappalà, G.; Zhu, C.; Zichichi, A.; Zullo, M.; Zullo, A.; Zuzel, G.

2018-03-01

Building on the successful experience in operating the DarkSide-50 detector, the DarkSide Collaboration is going to construct DarkSide-20k, a direct WIMP search detector using a two-phase Liquid Argon Time Projection Chamber (LAr TPC) with an active (fiducial) mass of 23 t (20 t). This paper describes a preliminary design for the experiment, in which the DarkSide-20k LAr TPC is deployed within a shield/veto with a spherical Liquid Scintillator Veto (LSV) inside a cylindrical Water Cherenkov Veto (WCV). This preliminary design provides a baseline for the experiment to achieve its physics goals, while further development work will lead to the final optimization of the detector parameters and an eventual technical design. Operation of DarkSide-50 demonstrated a major reduction in the dominant 39Ar background when using argon extracted from an underground source, before applying pulse shape analysis. Data from DarkSide-50, in combination with MC simulation and analytical modeling, shows that a rejection factor for discrimination between electron and nuclear recoils of >3 × 109 is achievable. This, along with the use of the veto system and utilizing silicon photomultipliers in the LAr TPC, are the keys to unlocking the path to large LAr TPC detector masses, while maintaining an experiment in which less than < 0.1 events (other than ν-induced nuclear recoils) is expected to occur within the WIMP search region during the planned exposure. DarkSide-20k will have ultra-low backgrounds than can be measured in situ, giving sensitivity to WIMP-nucleon cross sections of 1.2 × 10^{-47} cm2 (1.1 × 10^{-46} cm2) for WIMPs of 1 TeV/c 2 (10 TeV/c 2) mass, to be achieved during a 5 yr run producing an exposure of 100 t yr free from any instrumental background.

Effect of drag-reducing polymers on Tubing Performance Curve (TPC) in vertical gas-liquid flows

NARCIS (Netherlands)

Shoeibi Omrani, P.; Veltin, J.; Turkenburg, D.H.

2014-01-01

This paper discusses the effect of drag reducing polymers on the Tubing Performance Curve (TPC) of vertical air-water flows at near atmospheric conditions. The effect of polymer concentration, liquid and gas flow rates on the pressure drop curve (Tubing Performance Curve) was investigated

First performance results of the ALICE TPC Readout Control Unit 2

OpenAIRE

Zhao, Chengxin; Alme, Johan; Alt, Torsten; Appelshäuser, Harald; Bratrud, Lars Karlot Stubberud; Castro, Andrew; Costa, Filippo; David, Ernö; Gunji, Tako; Kirsch, S; Kiss, Tivadar; Langøy, Rune; Lien, Jørgen; Lippmann, C; Oskarsson, Anders

2016-01-01

- This paper presents the first performance results of the ALICE TPC Readout Control Unit 2 (RCU2). With the upgraded hardware typology and the new readout scheme in FPGA design, the RCU2 is designed to achieve twice the readout speed of the present Readout Control Unit. Design choices such as using the flash-based Microsemi Smartfusion2 FPGA and applying mitigation techniques in interfaces and FPGA design ensure a high degree of radiation tolerance. This paper presents the system level ir...

Detection and Identification of Marine Mammals in Passive Acoustic Recordings from SCORE using a Visual Processing Approach Established for HARP Data

Science.gov (United States)

2012-06-01

ship noise was to listen to the file. Sperm whale pulses sound like a metronome , very methodical, whereas ship noise in these frequencies sounds...by listening to the file. In both HARP and SCORE sperm whale clicks sound like a metronome . 34 We did not use the waveform as a way of

GIARPS@TNG: GIANO-B and HARPS-N together for a wider wavelength range spectroscopy

Science.gov (United States)

Claudi, R.; Benatti, S.; Carleo, I.; Ghedina, A.; Guerra, J.; Micela, G.; Molinari, E.; Oliva, E.; Rainer, M.; Tozzi, A.; Baffa, C.; Baruffolo, A.; Buchschacher, N.; Cecconi, M.; Cosentino, R.; Fantinel, D.; Fini, L.; Ghinassi, F.; Giani, E.; Gonzalez, E.; Gonzalez, M.; Gratton, R.; Harutyunyan, A.; Hernandez, N.; Lodi, M.; Malavolta, L.; Maldonado, J.; Origlia, L.; Sanna, N.; Sanjuan, J.; Scuderi, S.; Seemann, U.; Sozzetti, A.; Perez Ventura, H.; Hernandez Diaz, M.; Galli, A.; Gonzalez, C.; Riverol, L.; Riverol, C.

2017-08-01

Since 2012, thanks to the installation of the high-resolution echelle spectrograph in the optical range HARPS-N, the Italian telescope TNG (La Palma) became one of the key facilities for the study of the extrasolar planets. In 2014 TNG also offered GIANO to the scientific community, providing a near-infrared (NIR) cross-dispersed echelle spectroscopy covering 0.97-2.45μm at a resolution of 50000. GIANO, although designed for direct light-feed from the telescope at the Nasmyth-B focus, was provisionally mounted on the rotating building and connected via fibers to only available interface at the Nasmyth-A focal plane. The synergy between these two instruments is particularly appealing for a wide range of science cases, especially for the search of exoplanets around young and active stars and the characterisation of their atmosphere. Through the funding scheme "WOW" (a Way to Others Worlds), the Italian National Institute for Astrophysics (INAF) proposed to position GIANO at the focal station for which it was originally designed and the simultaneous use of these spectrographs with the aim to achieve high-resolution spectroscopy in a wide wavelength range (0.383-2.45μm) obtained in a single exposure, giving rise to the project called GIARPS (GIANO-B & HARPS-N). Because of its characteristics, GIARPS can be considered the first and unique worldwide instrument providing not only high resolution in a large wavelength band, but also a high-precision radial velocity measurement both in the visible and in the NIR arm, since in the next future GIANO-B will be equipped with gas absorption cells.

Magnetic Field Requirements for a Detector at the Linear Collider Using a TPC as Main Tracking Device

CERN Document Server

Klempt, W

2010-01-01

This note describes the requirements to the magnetic field which occur in an ILD like detector at ILC or CLIC. In particular we describe requirements introduced by choosing a TPC as main tracking detector.

Progress on a spherical TPC for low energy neutrino detection

International Nuclear Information System (INIS)

Aune, S; Colas, P; Deschamps, H; Dolbeau, J; Fanourakis, G; Ribas, E Ferrer; Enqvist, T; Geralis, T; Giomataris, Y; Gorodetzky, P; Gounaris, G J; Gros, M; Irastorza, I G; Kousouris, K; Lepeltier, V; Morales, J; Patzak, T; Paschos, E A; Salin, P; Savvidis, I; Vergados, J D

2006-01-01

The new concept of the spherical TPC aims at relatively large target masses with low threshold and background, keeping an extremely simple and robust operation. Such a device would open the way to detect the neutrino-nucleus interaction, which, although a standard process, remains undetected due to the low energy of the neutrino-induced nuclear recoils. The progress in the development of the first 1 m 3 prototype at Saclay is presented. Other physics goals of such a device could include supernova detection, low energy neutrino oscillations and study of non-standard properties of the neutrino, among others

Investigation of a Huffman-based compression algorithm for the ALICE TPC read-out in LHC Run 3

Energy Technology Data Exchange (ETDEWEB)

Klewin, Sebastian [Physikalisches Institut, University of Heidelberg (Germany); Collaboration: ALICE-Collaboration

2016-07-01

Within the scope of the ALICE upgrade towards the Run 3 of the Large Hadron Collider at CERN, starting in 2020, the ALICE Time Projection Chamber (TPC) will be reworked in order to allow for a continuous read-out. This rework includes not only a replacement of the current read-out chambers with Gas Electron Multiplier (GEM) technology, but also new front-end electronics. To be able to read out the whole data stream without loosing information, in particular without zero-suppression, a lossless compression algorithm, the Huffman encoding, was investigated and adapted to the needs of the TPC. In this talk, an algorithm, adapted for an FPGA implementation, is presented. We show its capability to reduce the data volume to less than 40% of its original size.

A Continuously Running High-Rate GEM-TPC for P-bar ANDA

International Nuclear Information System (INIS)

Boehmer, F.V.; Angerer, H.; Dorheim, S.; Hoeppner, C.; Ketzer, B.; Konorov, I.; Neubert, S.; Paul, S.; Vandenbroucke, M.; Zhang, X.; Berger, M.; Cusanno, F.; Fabbietti, L.; Lalik, R.; Beck, R.; Kaiser, D.; Lang, M.; Schmitz, R.; Walther, D.; Winnebeck, A.

2011-01-01

The P-bar ANDA fixed target experiment planned at FAIR will investigate fundamental questions of non-perturbative QCD. It makes use of a cooled antiproton beam (momentum: 1.5 to 15GeV/c) and will reach luminosities of up to 2.10 32 cm -2 s -1 , yielding a p-bar p-annihilation rate of 2.10 7 s -1 . One option for the central tracker of P-bar ANDA is a cylindrical, ungated, continuously running TPC with GEM-based gas amplification stage.

Music, singing and dancing in relation to the use of the harp and the ram’s horn or shofar in the Bible: What do we know about this?

Directory of Open Access Journals (Sweden)

Morakeng E.K. Lebaka

2014-10-01

Full Text Available There are many possible approaches to describing the effects and uses of music in a particular society. It would be a mistake to assume that music in the Bible is not the cement of social life and has no liturgical significance. The present study seeks to explore how people in ancient times employed music using the harp and the ram’s horn (shofar, to cope with roles that were open or never-ending in their demands. In particular, it focuses upon the role played by music in secular life as well as religious rituals, as described in the Bible. The method used was an extensive literature study of the Old and New Testament, textbooks and relevant peer reviewed journals, with a focus on both secular and religious reasons for singing, dancing and playing instruments. It was found that the Bible described the use of the harp and the ram’s horn associated with singing and dancing during celebrations, for military use, as well as mourning or lamentation. It was concluded that music using different instruments, including the harp and shofar, helped people to cope with the demands of everyday life and thus played an important role in both secular life and religious rituals in biblical times.

The liquid argon TPC for the ICARUS experiment

CERN Document Server

Arneodo, F

1997-01-01

The ICARUS project aims at the realisation of a large liquid argon TPC to be run at the Underground Laboratories of Gran Sasso in Italy. An intense R&D; activity has put on firm grounds this new detector technology and experimentally confirmed its feasibility on a few ton scale. Based on these solid achievements, the collaboration is now confident of being able to build and safely operate a multi-kton detector. The reseach program of the experiment involves the systematic study of a wide spectrum of physical phenomena covering many orders of magnitude in the energy deposited in the detector: from the few MeV of solar neutrino interactions, to the about one GeV of the proton decay and atmospheric neutrinos, up to the higher energies of neutrinos from accelerators.

ALICE TPC gas system is the first of the LHC experiments to be put on line

CERN Document Server

Maximilien Brice

2006-01-01

Picture 01 : the Physics Department's DT1 gas systems team in their laboratory. Picture 02 : Chilo Garabatos (ALICE) and Stefan Haider (PH-DT1-GS) in front of the gas system for the ALICE TPC which has just been put on line.

The GAPS Programme with HARPS-N at TNG. XV. A substellar companion around a K giant star identified with quasi-simultaneous HARPS-N and GIANO measurements

Science.gov (United States)

González-Álvarez, E.; Affer, L.; Micela, G.; Maldonado, J.; Carleo, I.; Damasso, M.; D'Orazi, V.; Lanza, A. F.; Biazzo, K.; Poretti, E.; Gratton, R.; Sozzetti, A.; Desidera, S.; Sanna, N.; Harutyunyan, A.; Massi, F.; Oliva, E.; Claudi, R.; Cosentino, R.; Covino, E.; Maggio, A.; Masiero, S.; Molinari, E.; Pagano, I.; Piotto, G.; Smareglia, R.; Benatti, S.; Bonomo, A. S.; Borsa, F.; Esposito, M.; Giacobbe, P.; Malavolta, L.; Martinez-Fiorenzano, A.; Nascimbeni, V.; Pedani, M.; Rainer, M.; Scandariato, G.

2017-10-01

Context. Identification of planetary companions of giant stars is made difficult because of the astrophysical noise, that may produce radial velocity variations similar to those induced by a companion. On the other hand any stellar signal is wavelength dependent, while signals due to a companion are achromatic. Aims: Our goal is to determine the origin of the Doppler periodic variations observed in the thick disk K giant star TYC 4282-605-1 by HARPS-N at the Telescopio Nazionale Galileo (TNG) and verify if they can be due to the presence of a substellar companion. Methods: Several methods have been used to exclude the stellar origin of the observed signal including detailed analysis of activity indicators and bisector and the analysis of the photometric light curve. Finally we have conducted an observational campaign to monitor the near infrared (NIR) radial velocity with GIANO at the TNG in order to verify whether the NIR amplitude variations are comparable with those observed in the visible. Results: Both optical and NIR radial velocities show consistent variations with a period at 101 days and similar amplitude, pointing to the presence of a companion orbiting the target. The main orbital properties obtained for our giant star with a derived mass of M = 0.97 ± 0.03M⊙ are MPsini = 10.78 ± 0.12MJ; P = 101.54 ± 0.05 days; e = 0.28 ± 0.01 and a = 0.422 ± 0.009 AU. The chemical analysis shows a significant enrichment in the abundance of Na I, Mg I, Al I and Si I while the rest of analyzed elements are consistent with the solar value demonstrating that the chemical composition corresponds with an old K giant (age = 10.1 Gyr) belonging to local thick disk. Conclusions: We conclude that the substellar companion hypothesis for this K giant is the best explanation for the observed periodic radial velocity variation. This study also shows the high potential of multi-wavelength radial velocity observations for the validation of planet candidates. Based on

A Continuously Running High-Rate GEM-TPC for P-bar ANDA

Energy Technology Data Exchange (ETDEWEB)

Boehmer, F.V., E-mail: felix.valentin.boehmer@cern.ch [Technische Universitaet Muenchen Physik Department, James-Franck-Strasse, 85748 Garching (Germany); Angerer, H.; Dorheim, S.; Hoeppner, C.; Ketzer, B.; Konorov, I.; Neubert, S.; Paul, S.; Vandenbroucke, M.; Zhang, X. [Technische Universitaet Muenchen Physik Department, James-Franck-Strasse, 85748 Garching (Germany); Berger, M.; Cusanno, F.; Fabbietti, L.; Lalik, R. [Excellence Cluster Universe, Muenchen (Germany); Beck, R.; Kaiser, D.; Lang, M.; Schmitz, R.; Walther, D.; Winnebeck, A. [Helmholtz-Institut fuer Strahlen- und Kernphysik, Bonn (Germany)

2011-06-15

The P-bar ANDA fixed target experiment planned at FAIR will investigate fundamental questions of non-perturbative QCD. It makes use of a cooled antiproton beam (momentum: 1.5 to 15GeV/c) and will reach luminosities of up to 2.10{sup 32}cm{sup -2}s{sup -1}, yielding a p-bar p-annihilation rate of 2.10{sup 7}s{sup -1}. One option for the central tracker of P-bar ANDA is a cylindrical, ungated, continuously running TPC with GEM-based gas amplification stage.

The efficacy of Jackson drain in the application to be a tunnel pleural catheter (TPC) in the management of malignant pleural effusion.

Science.gov (United States)

Tscheikuna, Jamsak; Thomrongpairoj, Preecha; Disayabutr, Suppareurg

2011-06-01

Malignant pleural effusion (MPE) is a common clinical problem in patients with advanced cancer and portends a poor prognosis, which means survival of less than six months. In June 1997, the US-FDA approved an indwelling TPC with a one-way drainage valve to be used in the management of MPE. Although popularity of this TPC has increased over the past few years, the experience with this device remains limited in Thai patients. One of the reasons is its high cost. Assess the efficacy and the safety of customary indwelling TPC by using Jackson drain in the management of patients with symptomatic MPE. Ten patients with symptomatic MPE were receiving these catheters (18 Fr Silicone catheters with 25 cm fenestrated length) to drain effusion via plastic vacuum bottles (250 ml) every other day or as needed to relieve dyspnea. The patient's dyspnic respiration, quality of life, and comfort during the catheter's application were quantified with a Borg score, the St. George Respiratory Disease Questionnaire (SGRQ), and the comfort's score, respectively. These parameters were recorded at initial (before insertion) and 2-week follow-up visit. Pain after 24 hours of each insertion was quantified by visual pain analogue scale (VPAS). Patients were followed until either death or catheter removal. The Borg score, SGRQ, and comfort's score showed significant improvement at 2-week visit (p drain was effective in the treatment of MPE as a TPC without early complications.

Tempering an Enlightened Educator: Frédéric-César de La Harpe at the Russian Imperial Court (1783–1795

Directory of Open Access Journals (Sweden)

Andrei Yu. Andreev

2017-12-01

Full Text Available Among all the educators who cared for him from his early childhood, Alexander I gave a particular honor to only one, the Swiss teacher Frédéric-César de La Harpe (1754–1838, who, invited to teach the French language, was further his instructor in geography, history, arithmetic, and geometry, as well as the foundations of philosophy. This Swiss teacher has been regarded in historical studies as the fortunate “chosen one” by Catherine II, who summoned him to direct Alexander’s education and who rewarded him accordingly afterwards. The present article peers into the backstage of the long educational process (1783–1795 in which he was engaged, revealing the less idyllic facts. Based on unpublished documents in Russian and Swiss archives, this study presents a picture of the place of an educator on the main stage of his activity, the Russian Imperial court, and thus the interplay of the history of practice and of ideas and their representations. Did La Harpe himself choose to work as an educator? Did Catherine II really search and find the Swiss teacher for his abilities? Did his teaching indeed represent a concretization of Catherine’s thoughts on this matter? And finally, how did La Harpe himself estimate his situation at the court, which was transformed into a “success story” only after 1814? This article, offering some answers to these questions, adds to the analysis the different circumstances of La Harpe’s appearance and later life at the court; the difficulties he faced in spite of the support of Catherine II, which was, regrettably, withdrawn unexpectedly; and, finally, the permanent discrepancies between his pedagogical ideals and the everyday studies in which he engaged.

Search for a QGP with a TPC spectrometer, and QGP signals predicted by new event generator

International Nuclear Information System (INIS)

Lindenbaum, S.J.

1988-01-01

The BNL/CCNY/Johns Hopkins/Rice Collaboration has developed and successfully tested a TPC Magnetic Spectrometer to search for OGP signals produced by ion beams at AGS. Test data with 14.5 GeV/c /times/ A Oxygen ions incident on a Pb target has been obtained. These include a 78-prong nuclear interaction in the MPS magnet which was pattern recognized with an efficiency ∼75%. A cascade and plasma event generator has also been developed, the predictions of which are used to illustrate how our technique can detect possible plasma signals at AGS and RHIC. A 4π tracking TPC magnetic spectrometer has been proposed for RHIC. The new event generator predicts striking central rapidity bump QGP signals at RHIC for p, /bar p/, π/sup +-/, K/sup +-/, etc., produced by 100 GeV/c /times/ A Au on Au collisions and these are presented. 2 refs., 13 figs., 1 tab

A GEM-TPC prototype with low-Noise highly integrated front-end electronics for linear collider studies

CERN Document Server

Kappler, Steffen; Kaminski, Jochen; Ledermann, Bernhard; Müller, Thomas; Ronan, Michael T; Ropelewski, Leszek; Sauli, Fabio; Settles, Ronald

2004-01-01

Connected to the linear collider project, studies on the readout of time projection chambers (TPCs) based on the gas electron multiplier (GEM) are ongoing. Higher granularity and intrinsically suppressed ion feedback are the major advantages of this technology. After a short discussion of these issues, we present the design of a small and very flexible TPC prototype, whose cylindrical drift volume can be equipped with endcaps of different gas detector types. An endcap with multi-GEM readout is currently set up and successfully operated with a low-noise highly integrated front-end electronics. We discuss results of measurements with this system in high intensity particle beams at CERN, where 99.3 plus or minus 0.2% single-pad-row efficiency could be achieved at an effective gain of 2.5 multiplied by 10**3 only, and spatial resolutions down to 63 plus or minus 3 mum could be demonstrated. Finally, these results are extrapolated to the high magnetic field in a linear collider TPC. 5 Refs.

Development of a TPC for energy and fluence references in low energies neutronic fields (from 8 keV to 5 MeV)

International Nuclear Information System (INIS)

Maire, Donovan

2015-01-01

In order to judge the measurement reliability, metrology requires to measure quantities with their uncertainties, in relation to a reference through a documented and unbroken chain of calibrations. In neutron radiation field, instrument response has to be known as a function of the neutron energy. Then detector calibrations are required using reference neutron fields. In France, primary reference neutron fields are held by the LNE-IRSN, at the Laboratory for Neutron Metrology and Dosimetry (LMDN). In order to improve reference neutron field characterization, the LNE-IRSN MIMAC μTPC has been developed. This detector is a Time Projection Chamber (TPC), using a gas at low pressure (30 mbar abs. to 1 bar abs.). Nuclear recoils are generated by neutron elastic scattering onto gas atoms. By measuring the nuclear recoil energy and scattering angle, the μTPC detector is able to measure the energy distribution of the neutron fluence between 8 keV and 5 MeV. The main challenge was to perform accurate spectrometry of neutron fields in the keV range, following a primary procedure. First of all, a metrological approach was followed in order to master every physical process taking part in the neutron detection. This approach led to develop the direct and inverse models, representing the detector response function and its inverse function respectively. Using this detailed characterization, the energy distribution of the neutron fluence has been measured for a continuous neutron field of 27 keV. The reconstructed energy is 28,2 ± 4,5 keV, the difference between μTPC integral fluence measurement and other measurement methods is less than 6%. The LNE-IRSN MIMAC μTPC system becomes the only one system able to measure simultaneously energy and fluence at energies lower than 100 keV, following a primary procedure. The project goal is then reached. These measurements at energies lower than 100 keV shows also a non-linearity between the ionization charge and the ion kinetic energy

TREX-DM: a low-background Micromegas-based TPC for low-mass WIMP detection

Energy Technology Data Exchange (ETDEWEB)

Iguaz, F.J.; Garza, J.G.; Castel, J.F.; Cebrian, S.; Dafni, T.; Garcia, J.A.; Irastorza, I.G.; Lagraba, A.; Luzon, G.; Peiro, A. [Universidad de Zaragoza, Grupo de Fisica Nuclear y Astroparticulas, Zaragoza (Spain); Aznar, F. [Universidad de Zaragoza, Grupo de Fisica Nuclear y Astroparticulas, Zaragoza (Spain); Universidad de Zaragoza, Centro Universitario de la Defensa, Zaragoza (Spain)

2016-10-15

If Dark Matter is made of Weakly Interacting Massive Particles (WIMPs) with masses below ∝20 GeV, the corresponding nuclear recoils in mainstream WIMP experiments are of energies too close, or below, the experimental threshold. Gas Time Projection Chambers (TPCs) can be operated with a variety of target elements, offer good tracking capabilities and, on account of the amplification in gas, very low thresholds are achievable. Recent advances in electronics and in novel radiopure TPC readouts, especially micro-mesh gas structure (Micromegas), are improving the scalability and low-background prospects of gaseous TPCs. Here we present TREX-DM, a prototype to test the concept of a Micromegas-based TPC to search for low-mass WIMPs. The detector is designed to host an active mass of ∝0.300 kg of Ar at 10 bar, or alternatively ∝0.160 kg of Ne at 10 bar, with an energy threshold below 0.4 keVee, and is fully built with radiopure materials. We will describe the detector in detail, the results from the commissioning phase on surface, as well as a preliminary background model. The anticipated sensitivity of this technique may go beyond current experimental limits for WIMPs of masses of 2-8 GeV. (orig.)

Gas pixel detector for X-ray observation

CERN Document Server

Attié, D; Chefdeville, M; Colas, P; Delagnes, E; Giomataris, Y; van der Graaf, H; Llopart, X; Timmermans, J; Visschers, J

2009-01-01

We report on the status of the R&D for a digital Time Projection Chamber (TPC) based on Micromegas (MICRO MEsh GAseous Structure) detectors using the CMOS chip TimePix as a direct readout anode protected by highly resistive a-Si:H layer. A small chamber was built as a demonstrator of the 2-D and 3-D imaging capabilities of this technique. We illustrate the new capabilities of this detector for X-ray observation with data taken from radioactive sources. This small TPC is a very useful tool both for studying gas properties thanks to its good efficiency for single electrons, and for reconstructing photoelectron direction for use as a soft X-ray polarimeter.

The WA105-3x1x1 m3 dual phase LAr-TPC demonstrator

CERN Document Server

Murphy, Sebastien

2016-11-15

The dual phase Liquid Argon Time Projection Chamber (LAr TPC) is the state-of-art technology for neutrino detection thanks to its superb 3D tracking and calorimetry performance. Its main feature is the charge amplification in gas argon which provides excellent signal-to-noise ratio. Electrons produced in the liquid argon are extracted in the gas phase. Here, a readout plane based on Large Electron Multiplier detectors provides amplification of the charges before its collection onto an anode with strip readout. The charge amplification enables constructing fully homoge- nous giant LAr-TPCs with tuneable gain, excellent charge imaging performance and increased sensitivity to low energy events. Following a staged approach the WA105 collaboration is con- structing a dual phase LAr-TPC with an active volume of 3x1x1m3 that will soon be tested with cosmic rays. Its construction and operation aims to test scalable solutions for the crucial aspects of this technology: ultra high argon purity in non-evacuable tank, la...

Search for “anomalies” from neutrino and anti-neutrino oscillations at $\\Delta_m^{2} ≈ 1eV^{2}$ with muon spectrometers and large LAr–TPC imaging detectors

CERN Document Server

Antonello, M; Baibussinov, B; Bilokon, H; Boffelli, F; Bonesini, M; Calligarich, E; Canci, N; Centro, S; Cesana, A; Cieslik, K; Cline, D B; Cocco, A G; Dequal, D; Dermenev, A; Dolfini, R; De Gerone, M; Dussoni, S; Farnese, C; Fava, A; Ferrari, A; Fiorillo, G; Garvey, G T; Gatti, F; Gibin, D; Gninenko, S; Guber, F; Guglielmi, A; Haranczyk, M; Holeczek, J; Ivashkin, A; Kirsanov, M; Kisiel, J; Kochanek, I; Kurepin, A; Łagoda, J; Lucchini, G; Louis, W C; Mania, S; Mannocchi, G; Marchini, S; Matveev, V; Menegolli, A; Meng, G; Mills, G B; Montanari, C; Nicoletto, M; Otwinowski, S; Palczewski, T J; Passardi, G; Perfetto, F; Picchi, P; Pietropaolo, F; Płonski, P; Rappoldi, A; Raselli, G L; Rossella, M; Rubbia, C; Sala, P; Scaramelli, A; Segreto, E; Stefan, D; Stepaniak, J; Sulej, R; Suvorova, O; Terrani, M; Tlisov, D; Van de Water, R G; Trinchero, G; Turcato, M; Varanini, F; Ventura, S; Vignoli, C; Wang, H G; Yang, X; Zani, A; Zaremba, K; Benettoni, M; Bernardini, P; Bertolin, A; Bozza, C; Brugnera, R; Cecchetti, A; Cecchini, S; Collazuol, G; Creti, P; Dal Corso, F; De Mitri, I; De Robertis, G; De Serio, M; Degli Esposti, L; Di Ferdinando, D; Dore, U; Dusini, S; Fabbricatore, P; Fanin, C; Fini, R A; Fiore, G; Garfagnini, A; Giacomelli, G; Giacomelli, R; Grella, G; Guandalini, C; Guerzoni, M; Kose, U; Laurenti, G; Laveder, M; Lippi, I; Loddo, F; Longhin, A; Loverre, P; Mancarella, G; Mandrioli, G; Margiotta, A; Marsella, G; Mauri, N; Medinaceli, E; Mengucci, A; Mezzetto, M; Michinelli, R; Muciaccia, M T; Orecchini, D; Paoloni, A; Pastore, A; Patrizii, L; Pozzato, M; Rescigno, R; Rosa, G; Simone, S; Sioli, M; Sirri, G; Spurio, M; Stanco, L; Stellacci, S; Surdo, A; Tenti, M; Togo, V; Ventura, M; Zago, M

2012-01-01

This proposal describes an experimental search for sterile neutrinos beyond the Standard Model with a new CERN-SPS neutrino beam. The experiment is based on two identical LAr-TPC's followed by magnetized spectrometers, observing the electron and muon neutrino events at 1600 and 300 m from the proton target. This project will exploit the ICARUS T600, moved from LNGS to the CERN "Far" position. An additional 1/4 of the T600 detector will be constructed and located in the "Near" position. Two spectrometers will be placed downstream of the two LAr-TPC detectors to greatly complement the physics capabilities. Spectrometers will exploit a classical dipole magnetic field with iron slabs, and a new concept air-magnet, to perform charge identification and muon momentum measurements in a wide energy range over a large transverse area. In the two positions, the radial and energy spectra of the nu_e beam are practically identical. Comparing the two detectors, in absence of oscillations, all cross sections and experimenta...

Assessment of the efficiency of SimPlate™ total plate count color indicator (TPC CI to quantify mesophilic aerobic microorganisms in pasteurized milk Avaliação da eficiência do SimPlate™ Total Plate Count Color Indicator (TPC CI para enumeração de microrganismos aeróbios mesófilos em leite pasteurizado

Directory of Open Access Journals (Sweden)

Luís Augusto Nero

2002-01-01

Full Text Available The SimPlate™ TPC CI system is a rapid method to count mesophilic aerobic microorganisms (MAM in foods, based on the use of resazurine to indicate bacterial growth. Its efficiency in pasteurized milk was evaluated using 142 pasteurized milk samples (38 type A, 43 type B and 61 type C collected in Londrina, PR. The standard plating method, using Plate Count Agar (PCA was used for comparison. The plates of both systems were incubated at 35ºC and read after 24h and 48h. The occurrence of false-positive and false-negative wells and the predominant microorganisms in them were also evaluated. The results were compared by simple correlation and mean variance analyses. The correlation (r and mean variance values were 0.6811 and 0.7583 for the results obtained after 24h, respectively, and 0.9126 and 0.0842 for the results obtained after 48h, respectively. These results indicate that the performance of the system increases when the plates are incubated for 48h. When the three types of milk were evaluated separately, these values were 0.9285 and 0.0817 for type A milk, 0.9231 and 0.0466 for type B milk and 0.7209 and 0.1082 for type C milk. These results indicate that the better the quality of the milk the better the performance of SimPlate™ TPC CI. False-negative wells, found more frequently in samples with high MAM counts, were caused by Gram positive microorganisms, poorly detected by the SimPlate™ TPC CI system because they grew slowly and had low reduction capacity. The results indicated a higher efficiency of the SimPlate™ TPC CI system in the reading at 48h.O sistema SimPlate™ TPC CI é um método rápido para enumeração de microrganismos aeróbios mesófilos (MAM em alimentos que utiliza a resazurina como substância indicadora de crescimento bacteriano. Para avaliar sua eficiência em leite pasteurizado, 142 amostras (38 de leite tipo A, 43 de leite tipo B e 61 de leite tipo C foram colhidas em Londrina, PR, e analisadas pelo Sim

Silicon ion interactions measured in the E-810 TPC at the AGS

International Nuclear Information System (INIS)

Love, W.A.; Eiseman, S.E.; Etkin, A.; Foley, K.J.; Hackenburg, R.W.; Longacre, R.S.; Morris, T.W.; Platner, E.D.; Saulys, A.C.; Bonner, B.E.; Buchanan, J.A.; Chiou, C.N.; Clement, J.M.; Corcoran, M.D.; Kruk, J.W.; Mutchler, G.S.; Nessi, M.; Nessi-Tedaldi, F.; Roberts, J.B.; Chan, C.S.; Kramer, M.A.; Zhao, K.; Hallman, T.J.; Madansky, L.; Lindenbaum, S.J.

1991-01-01

The tracking detector of AGS Experiment 810 is a three-piece Time Projection Chamber (TPC) which measures all charged tracks in the forward hemisphere of the nucleon-nucleon center of mass system, i.e. forward of 20 degrees in the lab. A cut at multiplicity 50 was used to select more central collisions, yielding 2291 events from the gold sample, 2170 from the copper. This corresponds to cross sections of 0.59 and 0.20 barns, respectively, defining the 'central' sample for the charged particle distributions presented here. (orig./HSI)

τ physics using the TPC/2γ facility at HiLum PEP

International Nuclear Information System (INIS)

Bloom, E.D.

1991-01-01

Plans for a TPC/2γ facility program using HiLum PEP for τ physics are presented. The detector and its performance are described in some detail. The possibilities for a τ physics program with an integrated luminosity of 1 fb -1 are discussed. The physics issues are reviewed, particularly the τ'1-prong' problem, and preliminary results on τ → ν τ K +- X + X - + ≥ 0 Neutrals are shown. The performance of HiLum PEP is also presented, and expectations for the future are discussed. (R.P.) 15 refs., 14 figs., 3 tabs

The ALICE TPC, a large 3-dimensional tracking device with fast readout for ultra-high multiplicity events

CERN Document Server

INSPIRE-00249819; Appelshauser, H.; Bablok, S.; Bialas, N.; Bolgen, R.; Bonnes, U.; Bramm, R.; Braun-Munzinger, P.; Campagnolo, R.; Christiansen, P.; Dobrin, A.; Engster, C.; Fehlker, D.; Foka, Y.; Frankenfeld, U.; Gaardhoje, J.J.; Garabatos, C.; Glassel, P.; Gonzalez Gutierrez, C.; Gros, P.; Gustafsson, H.A.; Helstrup, H.; Hoch, M.; Ivanov, M.; Janik, R.; Junique, A.; Kalweit, A.; Keidel, R.; Kniege, S.; Kowalski, M.; Larsen, D.T.; Lesenechal, Y.; Lenoir, P.; Lindegaard, N.; Lippmann, C.; Mager, M.; Mast, M.; Matyja, A.; Munkejord, M.; Musa, L.; Nielsen, B.S.; Nikolic, V.; Oeschler, H.; Olsen, E.K.; Oskarsson, A.; Osterman, L.; Pikna, M.; Rehman, A.; Renault, G.; Renfordt, R.; Rossegger, S.; Rohrich, D.; Roed, K.; Richter, M.; Rueshmann, G.; Rybicki, A.; Sann, H.; Schmidt, H.R.; Siska, M.; Sitar, B.; Soegaard, C.; Soltveit, H.K.; Soyk, D.; Stachel, J.; Stelzer, H.; Stenlund, E.; Stock, R.; Strmen, P.; Szarka, I.; Ullaland, K.; Vranic, D.; Veenhof, R.; Westergaard, J.; Wiechula, J.; Windelband, B.

2010-01-01

The design, construction, and commissioning of the ALICE Time-Projection Chamber (TPC) is described. It is the main device for pattern recognition, tracking, and identification of charged particles in the ALICE experiment at the CERN LHC. The TPC is cylindrical in shape with a volume close to 90 m^3 and is operated in a 0.5 T solenoidal magnetic field parallel to its axis. In this paper we describe in detail the design considerations for this detector for operation in the extreme multiplicity environment of central Pb--Pb collisions at LHC energy. The implementation of the resulting requirements into hardware (field cage, read-out chambers, electronics), infrastructure (gas and cooling system, laser-calibration system), and software led to many technical innovations which are described along with a presentation of all the major components of the detector, as currently realized. We also report on the performance achieved after completion of the first round of stand-alone calibration runs and demonstrate result...

A TPC-like readout method for high precision muon-tracking using GEM-detectors

Energy Technology Data Exchange (ETDEWEB)

Flierl, Bernhard; Biebel, Otmar; Bortfeldt, Jonathan; Hertenberger, Ralf; Klitzner, Felix; Loesel, Philipp; Mueller, Ralph [Ludwig-Maximilians-Universitaet Muenchen (Germany); Zibell, Andre [Julius-Maximilians-Universitaet Wuerzburg (Germany)

2016-07-01

Gaseous electron multiplier (GEM) detectors are well suited for tracking of charged particles. Three dimensional tracking in a single layer can be achieved by application of a time-projection-chamber like readout mode (μTPC), if the drift time of the electrons is measured and the position dependence of the arrival time is used to calculate the inclination angle of the track. To optimize the tracking capabilities for ion tracks drift gas mixtures with low drift velocity have been investigated by measuring tracks of cosmic muons in a compact setup of four GEM-detectors of 100 x 100 x 6 mm{sup 3} active volume each and an angular acceptance of -25 to 25 . The setup consists of three detectors with two-dimensional strip readout layers of 0.4 mm pitch and one detector with a single strip readout layer of 0.25 mm pitch. All strips are readout by APV25 frontend boards and the amplification stage in the detectors consists of three GEM-foils. Tracks are reconstructed by the μTPC-method in one of the detectors and are then compared to the prediction from the other three detectors defined by the center of charge in every detector. We report our study of Argon and Helium based noble gas mixtures with carbon-dioxide as quencher.

Space charge calibration of the ALICE TPC operated with an open gating grid

Energy Technology Data Exchange (ETDEWEB)

Hellbaer, Ernst [Institut fuer Kernphysik, Goethe-Universitaet Frankfurt (Germany); Ivanov, Marian [GSI (Germany); Wiechula, Jens [Universitaet Tuebingen (Germany); Collaboration: ALICE-Collaboration

2015-07-01

The Time Projection Chamber (TPC) is the main particle identification detector of the ALICE experiment at the CERN LHC. High interaction rates of 50 kHz in Pb-Pb during the Run 3 period after 2020 require a major upgrade of the TPC readout. The currently used Multiwire Proportional Chambers (MWPCs) will be replaced by readout chambers (ROCs) based on Gas Electron Multiplier (GEM) technology which will be operated in a continuous mode. While the gating grid of the MWPCs prevents the positive ions of the amplification region from entering the drift volume, the GEM-based ROCs will introduce an ion backflow (IBF) of about 1%. In combination with the high-luminosity environment, this amount of back-drifting ions results in a considerable space charge density which distorts the drift path of the primary ionisation electrons significantly. In order to still provide a high tracking efficiency and cluster-to-track association, an efficient calibration scheme will be implemented. As a test ground for the new calibration scheme, pp collision data was taken during Run 1 with the gating grid operated in a transparent mode allowing the ions to enter the drift volume. The measured space point distortions due to the space charge are presented together with the corrected data and compared to simulations for Run 3.

Neutron Fluence and Energy Reconstruction with the LNE-IRSN/MIMAC Recoil Detector MicroTPC at 27 keV

Energy Technology Data Exchange (ETDEWEB)

Maire, D.; Lebreton, L.; Querre, Ph. [Institute for Radioprotection and Nuclear Safety - IRSN, site of Cadarache, 13115 Saint Paul lez Durance (France); Bosson, G.; Guillaudin, O.; Muraz, J.F.; Riffard, Q.; Santos, D. [Laboratoire de Physique Subatomique et de Cosmologie - LPSCCNRSIN2P3/ UJF/INP, 38000 Grenoble (France)

2015-07-01

The French Institute for Radiation protection and Nuclear Safety (IRSN), designated by the French Metrology Institute (LNE) for neutron metrology, is developing a time projection chamber using a Micromegas anode: microTPC. This work is carried out in collaboration with the Laboratory of Subatomic Physics and Cosmology (LPSC). The aim is to characterize the energy distribution of neutron fluence in the energy range 8 keV - 5 MeV with a primary procedure. The time projection chambers are gaseous detectors able to measure charged particles energy and to reconstruct their track if a pixelated anode is used. In our case, the gas is used as a (n, p) converter in order to detect neutrons down to few keV. Coming from elastic collisions with neutrons, recoil protons lose a part of their kinetic energy by ionizing the gas. The ionization electrons are drifted toward a pixelated anode (2D projection), read at 50 MHz by a self-triggered electronic system to obtain the third track dimension. The neutron energy is reconstructed event by event thanks to proton scattering angle and proton energy measurements. The scattering angle is deduced from the 3D track. The proton energy is obtained by charge collection measurements, knowing the ionization quenching factor (i.e. the part of proton kinetic energy lost by ionizing the gas). The fluence is calculated thanks to the detected events number and the simulation of the detector response. The μTPC is a new reliable detector able to measure energy distribution of the neutron fluence without unfolding procedure or prior neutron calibration contrary to usual gaseous counters. The microTPC is still being developed and measurements have been carried out at the AMANDE facility, with neutrons energies going from 8 keV to 565 keV. After the context and the μ-TPC working principle presentation, measurements of the neutron energy and fluence at 27 keV and 144 keV are shown and compared to the complete detector response simulation. This work

HADES RV Programme with HARPS-N at TNG. V. A super-Earth on the inner edge of the habitable zone of the nearby M dwarf GJ 625

Science.gov (United States)

Suárez Mascareño, A.; González Hernández, J. I.; Rebolo, R.; Velasco, S.; Toledo-Padrón, B.; Affer, L.; Perger, M.; Micela, G.; Ribas, I.; Maldonado, J.; Leto, G.; Zanmar Sanchez, R.; Scandariato, G.; Damasso, M.; Sozzetti, A.; Esposito, M.; Covino, E.; Maggio, A.; Lanza, A. F.; Desidera, S.; Rosich, A.; Bignamini, A.; Claudi, R.; Benatti, S.; Borsa, F.; Pedani, M.; Molinari, E.; Morales, J. C.; Herrero, E.; Lafarga, M.

2017-09-01

We report the discovery of a super-Earth orbiting at the inner edge of the habitable zone of the star GJ 625 based on the analysis of the radial-velocity (RV) time series from the HARPS-N spectrograph, consisting of 151 HARPS-N measurements taken over 3.5 yr. GJ 625 b is a planet with a minimum mass Msini of 2.82 ± 0.51 M⊕ with an orbital period of 14.628 ± 0.013 days at a distance of 0.078 AU from its parent star. The host star is the quiet M2 V star GJ 625, located at 6.5 pc from the Sun. We find the presence of a second radial-velocity signal in the range 74-85 days that we relate to stellar rotation after analysing the time series of Ca II H&K and Hα spectroscopic indicators, the variations of the FWHM of the CCF, and the APT2 photometric light curves. We find no evidence linking the short-period radial-velocity signal to any activity proxy. Based on observations made with the Italian Telescopio Nazionale Galileo (TNG), operated on the island of La Palma by the INAF - Fundación Galileo Galilei at the Roche de Los Muchachos Observatory of the Instituto de Astrofísica de Canarias (IAC); photometric observations made with the robotic telescope APT2 (within the EXORAP programme) located at Serra La Nave on Mt. Etna; and lucky imaging observations made with the Telescopio Carlos Sánchez operated on the island of Tenerife by the Instituto de Astrofísica de Canarias in the Spanish Observatorio del Teide.Tables A.1-A.5 are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/605/A92

Dedicated supernova detection by a network of neutral current spherical TPC detectors

International Nuclear Information System (INIS)

Vergados, J. D.; Giomataris, Y.

2007-01-01

Supernova neutrinos can easily be detected by a spherical gaseous TPC detector measuring very low energy nuclear recoils. The expected rates are quite large for a neutron-rich target since the neutrino-nucleus neutral current interaction yields a coherent contribution of all neutrons. As a matter of fact, for a typical supernova at 10 kpc, about 1000 events are expected using a spherical detector of radius 4 m with Xe gas at a pressure of 10 atm. A worldwide network of several such simple, stable, and low-cost supernova detectors with a running time of a few centuries is quite feasible

Measurement of the production of charged pions by protons on a tantalum target

CERN Document Server

Catanesi, M.G.; Edgecock, R.; Ellis, Malcolm; Robbins, S.; Soler, F.J.P.; Gossling, C.; Bunyatov, S.; Krasnoperov, A.; Popov, B.; Serdiouk, V.; Tereschenko, V.; Di Capua, E.; Vidal-Sitjed, G.; Artamonov, A.; Arce, P.; Giani, S.; Gilardoni, S.; Gorbunov, P.; Grant, A.; Grossheim, A.; Gruber, P.; Ivanchenko, V.; Kayis-Topaksu, A.; Panman, J.; Papadopoulos, I.; Pasternak, J.; Tcherniaev, E.; Tsukerman, I.; Veenhof, R.; Wiebusch, C.; Zucchelli, P.; Blondel, A.; Borghi, S.; Campanelli, M.; Morone, M.C.; Prior, G.; Schroeter, R.; Engel, R.; Meurer, C.; Kato, I.; Gastaldi, U.; Mills, G.B.; Graulich, J.S.; Gregoire, G.; Bonesini, M.; De Min, A.; Ferri, F.; Paganoni, M.; Paleari, F.; Kirsanov, M.; Bagulya, A.; Grichine, V.; Polukhina, N.; Palladino, V.; Coney, L.; Schmitz, D.; Barr, G.; De Santo, A.; Pattison, C.; Zuber, K.; Bobisut, F.; Gibin, D.; Guglielmi, A.; Mezzetto, M.; Dumarchez, J.; Vannucci, F.; Dore, U.; Orestano, D.; Pastore, F.; Tonazzo, A.; Tortora, L.; Booth, C.; Buttar, C.; Hodgson, P.; Howlett, L.; Bogomilov, M.; Chizhov, M.; Kolev, D.; Tsenov, R.; Apollonio, M.; Chimenti, P.; Giannini, G.; Santin, G.; Burguet-Castell, J.; Cervera-Villanueva, A.; Gomez-Cadenas, J.J.; Martin-Albo, J.; Novella, P.; Sorel, M.; Tornero, A.

2007-01-01

A measurement of the double-differential cross-section for the production of charged pions in proton--tantalum collisions emitted at large angles from the incoming beam direction is presented. The data were taken in 2002 with the HARP detector in the T9 beam line of the CERN PS. The pions were produced by proton beams in a momentum range from 3 \\GeVc to 12 \\GeVc hitting a tantalum target with a thickness of 5% of a nuclear interaction length. The angular and momentum range covered by the experiment ($100 \\MeVc \\le p < 800 \\MeVc$ and $0.35 \\rad \\le \\theta <2.15 \\rad$) is of particular importance for the design of a neutrino factory. The produced particles were detected using a small-radius cylindrical time projection chamber (TPC) placed in a solenoidal magnet. Track recognition, momentum determination and particle identification were all performed based on the measurements made with the TPC. An elaborate system of detectors in the beam line ensured the identification of the incident particles. Results a...

Measurement of 1.7–74 MeV polarised γ rays with the HARPO TPC

Energy Technology Data Exchange (ETDEWEB)

Geerebaert, Y., E-mail: yannick.geerebaert@polytechnique.fr [LLR, École Polytechnique, CNRS/IN2P3, Palaiseau (France); Gros, Ph., E-mail: philippe.gros@llr.in2p3.fr [LLR, École Polytechnique, CNRS/IN2P3, Palaiseau (France); Amano, S. [LASTI, University of Hyôgo (Japan); Attié, D. [CEA, Irfu, CEA-Saclay (France); Bernard, D.; Bruel, P. [LLR, École Polytechnique, CNRS/IN2P3, Palaiseau (France); Calvet, D.; Colas, P. [CEA, Irfu, CEA-Saclay (France); Daté, S. [JASRI/SPring8 (Japan); Delbart, A. [CEA, Irfu, CEA-Saclay (France); Frotin, M.; Giebels, B. [LLR, École Polytechnique, CNRS/IN2P3, Palaiseau (France); Götz, D. [AIM, CEA/DSM-CNRS – Université Paris Diderot (France); IRFU/Service d' Astrophysique, CEA-Saclay (France); Hashimoto, S. [LASTI, University of Hyôgo (Japan); Horan, D. [LLR, École Polytechnique, CNRS/IN2P3, Palaiseau (France); Kotaka, T. [LASTI, University of Hyôgo (Japan); Louzir, M. [LLR, École Polytechnique, CNRS/IN2P3, Palaiseau (France); Minamiyama, Y.; Miyamoto, S. [LASTI, University of Hyôgo (Japan); Ohkuma, H. [JASRI/SPring8 (Japan); and others

2017-02-11

Current γ-ray telescopes based on photon conversions to electron-positron pairs, such as Fermi, use tungsten converters. They suffer of limited angular resolution at low energies, and their sensitivity drops below 1 GeV. The low multiple scattering in a gaseous detector gives access to higher angular resolution in the MeV–GeV range, and to the linear polarisation of the photons through the azimuthal angle of the electron-positron pair. HARPO is an R&D programme to characterise the operation of a TPC (Time Projection Chamber) as a high angular-resolution and sensitivity telescope and polarimeter for γ rays from cosmic sources. It represents a first step towards a future space instrument. A 30 cm cubic TPC demonstrator was built, and filled with 2 bar argon-based gas. It was put in a polarised γ-ray beam at the NewSUBARU accelerator in Japan in November 2014. Data were taken at different photon energies from 1.7 MeV to 74 MeV, and with different polarisation configurations. The electronics setup is described, with an emphasis on the trigger system. The event reconstruction algorithm is quickly described, and preliminary measurements of the polarisation of 11 MeV photons are shown.

Spectrally resolved detection of sodium in the atmosphere of HD 189733b with the HARPS spectrograph

Science.gov (United States)

Wyttenbach, A.; Ehrenreich, D.; Lovis, C.; Udry, S.; Pepe, F.

2015-05-01

results pave the way for an in-depth characterization of physical conditions in the atmospheres of many exoplanetary systems with future spectrographs such as ESPRESSO on the VLT or HiReS and METIS on the E-ELT. Using observations with the Harps spectrograph from the ESO 3.6 m installed at La Silla, in Chile, under the allocated programmes 072.C-0488(E), 079.C-0828(A) and 079.C-0127(A).

{sup 11}C- and {sup 18}F Production at TPC RK2 Laboratory

Energy Technology Data Exchange (ETDEWEB)

Solin, O.; Johansson, S.; Eriksson, P-O.; Rajander, J.; Kokkomäki, E.; Helin, S.; Arponen, E.; Aromaa, J.; Savisto, N.; Bergman, J.; Heselius, S-J. [Turku PET Centre, Radiopharmaceutical Chemistry Laboratory and Accelerator Laboratory, Porthaninkatu 3, 20500 Turku (Finland)

2009-07-01

Four gas targets for production of [{sup 11}C]CO{sub 2} and [{sup 11}C]CH{sub 4} as well as static and one circulating water target for [{sup 18}F]fluoride production have been installed on the external beam line of the CC18/9 cyclotron (Efremov Institute for Electrophysical Apparatuses, St. Petersburg, Russia) at TPC. The cyclotron is capable of accelerating 18 MeV protons (9 MeV deuterons) at particle beam intensities in excess of 100 μA. The aim with these radionuclide production systems is high yield, high specific radioactivity precursor production for PET radiopharmaceuticals.

Search for anomalies in the neutrino sector with muon spectrometers and large LArTPC imaging detectors at CERN

CERN Document Server

Antonello, A.; Baibussinov, B.; Bilokon, H.; Boffelli, F.; Bonesini, M.; Calligarich, E.; Canci, N.; Centro, S.; Cesana, A.; Cieslik, K.; Cline, D.B.; Cocco, A.G.; Dequal, D.; Dermenev, A.; Dolfini, R.; De Gerone, M.; Dussoni, S.; Farnese, C.; Fava, A.; Ferrari, A.; Fiorillo, G.; Garvey, G.T.; Gatti, F.; Gibin, D.; Gninenko, S.; Guber, F.; Guglielmi, A.; Haranczyk, M.; Holeczek, J.; Ivashkin, A.; Kirsanov, M.; Kisiel, J.; Kochanek, I.; Kurepin, A.; Lagoda, J.; Lucchini, G.; Louis, W.C.; Mania, S.; Mannocchi, G.; Marchini, S.; Matveev, V.; Menegolli, A.; Meng, G.; Mills, G.B.; Montanari, C.; Nicoletto, M.; Otwinowski, S.; Palczewki, T.J.; Passardi, G.; Perfetto, F.; Picchi, P.; Pietropaolo, F.; Plonski, P.; Rappoldi, A.; Raselli, G.L.; Rossella, M.; Rubbia, C.; Sala, P.; Scaramelli, A.; Segreto, E.; Stefan, D.; Stepaniak, J.; Sulej, R.; Suvorova, O.; Terrani, M.; Tlisov, D.; Van de Water, R.G.; Trinchero, G.; Turcato, M.; Varanini, F.; Ventura, S.; Vignoli, C.; Wang, H.G.; Yang, X.; Zani, A.; Zaremba, K; Benettoni, M.; Bernardini, P.; Bertolin, A.; Brugnera, R.; Calabrese, M.; Cecchetti, A.; Cecchini, S.; Collazuol, G.; Creti, P.; Corso, F.Dal; Del Prete, A.; De Mitri, I.; De Robertis, G.; De Serio, M.; Esposti, L.Degli; Di Ferdinando, D.; Dore, U.; Dusini, S.; Fabbricatore, P.; Fanin, C.; Fini, R.A.; Fiore, G.; Garfagnini, A.; Giacomelli, G.; Giacomelli, R.; Guandalini, C.; Guerzoni, M.; Kose, U.; Laurenti, G.; Laveder, M.; Lippi, I.; Loddo, F.; Longhin, A.; Loverre, P.; Mancarella, G.; Mandrioli, G.; Margiotta, A.; Marsella, G.; Mauri, N.; Medinaceli, E.; Mengucci, A.; Mezzetto, M.; Michinelli, R.; Muciaccia, M.T.; Orecchini, D.; Paoloni, A.; Papadia, G.; Pastore, A.; Patrizii, L.; Pozzato, M.; Rosa, G.; Sahnounm, Z.; Simone, S.; Sioli, M.; Sirri, G.; Spurio, M.; Stanco, L.; Surdo, A.; Tenti, M.; Togo, V.; Ventura, M.; Zago, M.

2012-01-01

A new experiment with an intense ~2 GeV neutrino beam at CERN SPS is proposed in order to definitely clarify the possible existence of additional neutrino states, as pointed out by neutrino calibration source experiments, reactor and accelerator experiments and measure the corresponding oscillation parameters. The experiment is based on two identical LAr-TPCs complemented by magnetized spectrometers detecting electron and muon neutrino events at Far and Near positions, 1600 m and 300 m from the proton target, respectively. The ICARUS T600 detector, the largest LAr-TPC ever built with a size of about 600 ton of imaging mass, now running in the LNGS underground laboratory, will be moved at the CERN Far position. An additional 1/4 of the T600 detector (T150) will be constructed and located in the Near position. Two large area spectrometers will be placed downstream of the two LAr-TPC detectors to perform charge identification and muon momentum measurements from sub-GeV to several GeV energy range, greatly comple...

Recent advances with a hybrid micro-pattern gas detector operated in low pressure H2 and He, for AT-TPC applications

Directory of Open Access Journals (Sweden)

Cortesi Marco

2018-01-01

Full Text Available In view of a possible application as a charge-particle track readout for an Active-Target Time Projection Chamber (AT-TPC, the operational properties and performances of a hybrid Micro-Pattern Gaseous Detector (MPGD were investigated in pure low-pressure Hydrogen (H2 and Helium (He. The detector consists of a MICROMEsh GAseous Structure (MICROMEGAS coupled to a two-cascade THick Gaseous Electron Multiplier (THGEM as a pre-amplification stage. This study reports the effective gain dependence of the hybrid-MPGD at relevant pressure (in the range of 200-760 torr for different detector arrangements. The results of this work are relevant in the field of avalanche mechanism in low-pressure, low-mass noble gases, in particularly for applications of MPGD end-cap readout for active-target Time Projection Chambers (TPC in the field of nuclear physics and nuclear astrophysics.

Operation of a LAr-TPC equipped with a multilayer LEM charge readout

Science.gov (United States)

Baibussinov, B.; Centro, S.; Farnese, C.; Fava, A.; Gibin, D.; Guglielmi, A.; Meng, G.; Pietropaolo, F.; Varanini, F.; Ventura, S.; Zatrimaylov, K.

2018-03-01

A novel detector for ionization signals in a single phase LAr-TPC has been experimented in the ICARINO test facility at the INFN Laboratories in Legnaro. It is based on the adoption of a multilayer Large Electron Multiplier (LEM) replacing the traditional anodic wire arrays. Cosmic muon tracks were detected allowing the measurement of energy deposition and a first determination of the signal to noise ratio. The analysis of the recorded events demonstrated the 3D reconstruction capability of this device for ionizing events in liquid Argon. The collected fraction of ionization charge is close to about 90%, with signal to noise ratio similar to that measured with more traditional wire chambers.

Hand-assisted retroperitoneoscopic versus standard laparoscopic donor nephrectomy: HARP-trial

Directory of Open Access Journals (Sweden)

Alwayn Ian PJ

2010-03-01

Full Text Available Abstract Background Transplantation is the only treatment offering long-term benefit to patients with chronic kidney failure. Live donor nephrectomy is performed on healthy individuals who do not receive direct therapeutic benefit of the procedure themselves. In order to guarantee the donor's safety, it is important to optimise the surgical approach. Recently we demonstrated the benefit of laparoscopic nephrectomy experienced by the donor. However, this method is characterised by higher in hospital costs, longer operating times and it requires a well-trained surgeon. The hand-assisted retroperitoneoscopic technique may be an alternative to a complete laparoscopic, transperitoneal approach. The peritoneum remains intact and the risk of visceral injuries is reduced. Hand-assistance results in a faster procedure and a significantly reduced operating time. The feasibility of this method has been demonstrated recently, but as to date there are no data available advocating the use of one technique above the other. Methods/design The HARP-trial is a multi-centre randomised controlled, single-blind trial. The study compares the hand-assisted retroperitoneoscopic approach with standard laparoscopic donor nephrectomy. The objective is to determine the best approach for live donor nephrectomy to optimise donor's safety and comfort while reducing donation related costs. Discussion This study will contribute to the evidence on any benefits of hand-assisted retroperitoneoscopic versus standard laparoscopic donor nephrectomy. Trial Registration Dutch Trial Register NTR1433

Development and construction of a large TPC prototype for the ILC and study of τ polarisation in τ decays with the ILD detector

International Nuclear Information System (INIS)

Schade, Peter

2009-11-01

This thesis presents two studies which have been made in the framework of the detector development for the International Large Detector (ILD). In the preparation phase for the ILD, prototype studies are performed to develop and optimise the sub-detector technologies which will come into operation. Complementary to these hardware studies, expected physics scenarios are being investigated in full detector simulations. These simulations demonstrate the physics potential of the detector concept and are a benchmark for the detector and the accelerator design. The first part of this thesis gives an introduction to the physics questions addressed to the ILC. Also, the machine and the ILD detector concept are presented. The second part is dedicated to the development and the construction to a large Time Projection Chamber (TPC) prototype (LP). A TPC is foreseen as one of ILD's sub-detectors and shall measure the trajectories of charged particles with an accuracy unprecedented by TPCs operated before. The new prototype offers an infrastructure for the development of modern TPC readout structures which can fulfil the required criteria. Before construction, the design plans of the LP have been optimised for a low material budget of the structure and a very homogeneous drift field. During the manufacturing of the LP, experience with construction techniques has been gained for the construction of the ILD TPC. The third part deals with a simulation study for a polarisation measurement of τ leptons in the process e + e - → τ 1 τ 1 → χ 1 0 χ 1 0 ττ. Here, the τ 1 is the supersymmetric partner of the τ lepton. This simulation study shows the feasibility of the measurement in the chosen SUSY scenario and estimates the accuracy to be expected. Both studies address in particular the track reconstruction capabilities of the ILD detector. Conclusions of the discussed studies and an outlook are presented in part IV. (orig.)

Accurate gamma and MeV-electron track reconstruction with an ultra-low diffusion Xenon/TMA TPC at 10 atmospheres

CERN Document Server

González-Díaz, Diego; Borges, F.I.G.; Camargo, M.; Cárcel, S.; Cebrián, S.; Cervera, A.; Conde, C.A.N.; Dafni, T.; Díaz, J.; Esteve, R.; Fernandes, L.M.P.; Ferrario, P.; Ferreira, A.L.; Freitas, E.D.C.; Gehman, V.M.; Goldschmidt, A.; Gómez-Cadenas, J.J.; Gutiérrez, R.M.; Hauptman, J.; Hernando Morata, J.A.; Herrera, D.C.; Irastorza, I.G.; Labarga, L.; Laing, A.; Liubarsky, I.; Lopez-March, N.; Lorca, D.; Losada, M.; Luzón, G.; Marí, A.; Martín-Albo, J.; Martínez-Lema, G.; Martínez, A.; Miller, T.; Monrabal, F.; Monserrate, M.; Monteiro, C.M.B.; Mora, F.J.; Moutinho, L.M.; Muñoz Vidal, J.; Nebot-Guinot, M.; Nygren, D.; Oliveira, C.A.B.; Pérez, J.; Pérez Aparicio, J.L.; Querol, M.; Renner, J.; Ripoll, L.; Rodríguez, J.; Santos, F.P.; dos Santos, J.M.F.; Serra, L.; Shuman, D.; Simón, A.; Sofka, C.; Sorel, M.; Toledo, J.F.; Torrent, J.; Tsamalaidze, Z.; Veloso, J.F.C.A.; Villar, J.A.; Webb, R.; White, J.T.; Yahlali, N.; Azevedo, C.; Aznar, F.; Calvet, D.; Castel, J.; Ferrer-Ribas, E.; García, J.A.; Giomataris, I.; Gómez, H.; Iguaz, F.J.; Lagraba, A.; Le Coguie, A.; Mols, J.P.; Şahin, Ö.; Rodríguez, A.; Ruiz-Choliz, E.; Segui, L.; Tomás, A.; Veenhof, R.

2015-01-01

We report the performance of a 10 atm Xenon/trimethylamine time projection chamber (TPC) for the detection of X-rays (30 keV) and gamma-rays (0.511-1.275 MeV) in conjunction with the accurate tracking of the associated electrons. When operated at such a high pressure and in 1%-admixtures, trimethylamine (TMA) endows Xenon with an extremely low electron diffusion (1.3 +-0.13 mm-sigma (longitudinal), 0.8 +-0.15 mm-sigma (transverse) along 1 m drift) besides forming a convenient Penning-Fluorescent mixture. The TPC, that houses 1.1 kg of gas in its active volume, operated continuously for 100 live-days in charge amplification mode. The readout was performed through the recently introduced microbulk Micromegas technology and the AFTER chip, providing a 3D voxelization of 8mm x 8mm x 1.2mm for approximately 10 cm/MeV-long electron tracks. This work was developed as part of the R&D program of the NEXT collaboration for future detector upgrades in the search of the 0bbnu decay in 136Xe, specifically those based ...

Direct Dark Matter Detection through the use of a Xenon Based TPC Detector

Science.gov (United States)

Daniel, Jonathan; Akerib, Daniel; LZ group at SLAC

2018-01-01

The vast majority of matter in the universe is unaccounted for. Only 15% of the universe's mass density is visible matter, while the other 85% is Dark Matter (DM). The Weakly Interacting Massive Particle (WIMP) is currently the frontrunner of the DM candidates. The Large Underground Xenon (LUX) and next generation LUX-ZEPLIN (LZ) experiments are designed to directly detect WIMPs. Both experiments are xenon-based Time Projection Chambers (TPC) used to observe possible WIMP interactions. These interactions produce photons and electrons with the photons being collected in a set of two photomultiplier tube (PMT) arrays and the electrons drifted upwards in the detector by a strong electric field to create a secondary production of photons in gaseous xenon. These two populations of photons are classified as S1 and S2 signals, respectively. Using these signals we reconstruct the energy and position of the interaction and in doing so we can eliminate background events that would otherwise “light up” the detector. My participation in the experiment, while at SLAC, was the creation of the grids that produce the large electric field, along with additional lab activities aimed at testing the grids. While at Stan State, I work on background modeling in order to distinguish a possible WIMP signal from ambient backgrounds.

Process to process communication over Fastbus in the data acquisition system of the ALEPH TPC

International Nuclear Information System (INIS)

Lusiani, A.

1994-01-01

The data acquisition system of the ALEPH TPC includes a VAX/VMS computer cluster and 36 intelligent Fastbus modules (ALEPH TPPS) running the OS9 multitasking real-time operating system. Dedicated software has been written in order to reliably exchange information over Fastbus between the VAX/VMS cluster and the 36 TPPs to initialize and co-ordinate the microprocessors, and to monitor and debug their operation. The functionality and the performance of this software will be presented together with an overview of the application that rely on it

HADES RV Programme with HARPS-N at TNG. VI. GJ 3942 b behind dominant activity signals

Science.gov (United States)

Perger, M.; Ribas, I.; Damasso, M.; Morales, J. C.; Affer, L.; Suárez Mascareño, A.; Micela, G.; Maldonado, J.; González Hernández, J. I.; Rebolo, R.; Scandariato, G.; Leto, G.; Zanmar Sanchez, R.; Benatti, S.; Bignamini, A.; Borsa, F.; Carbognani, A.; Claudi, R.; Desidera, S.; Esposito, M.; Lafarga, M.; Martinez Fiorenzano, A. F.; Herrero, E.; Molinari, E.; Nascimbeni, V.; Pagano, I.; Pedani, M.; Poretti, E.; Rainer, M.; Rosich, A.; Sozzetti, A.; Toledo-Padrón, B.

2017-12-01

Context. Short- to mid-term magnetic phenomena on the stellar surface of M-type stars can resemble the effects of planets in radial velocity data, and may also hide them. Aims: We analyze 145 spectroscopic HARPS-N observations of GJ 3942 taken over the past five years and additional photometry in order to disentangle stellar activity effects from genuine Doppler signals as a result of the orbital motion of the star around the common barycenter with its planet. Methods: To achieve this, we use the common methods of pre-whitening, and treat the correlated red noise by a first-order moving average term and by Gaussian-process regression following an MCMC analysis. Results: We identify the rotational period of the star at 16.3 days and discover a new super-Earth, GJ 3942 b, with an orbital period of 6.9 days and a minimum mass of 7.1 M⊕. An additional signal in the periodogram of the residuals is present, but at this point we cannot claim with sufficient significance that it is related to a second planet. If confirmed, this planet candidate would have a minimum mass of 6.3 M⊕ and a period of 10.4 days, which might indicate a 3:2 mean-motion resonance with the inner planet. Based on observations made with the Italian Telescopio Nazionale Galileo (TNG), operated on the island of La Palma by the INAF - Fundación Galileo Galilei at the Roque de los Muchachos Observatory of the Instituto de Astrofísica de Canarias (IAC); photometric observations from the APACHE array located at the Astronomical Observatory of the Aosta Valley; photometric observations made with the robotic APT2 (within the EXORAP program) located at Serra La Nave on Mt. Etna.Table 9 is only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/608/A63

New read-out electronics for ICARUS-T600 liquid Argon TPC. Description, simulation and tests of the new front-end and ADC system arXiv

CERN Document Server

Bagby, L.; Bellini, V.; Bonesini, M.; Braggiotti, A.; Castellani, L.; Centro, S.; Cervi, T.; Cocco, A.G.; Fabris, F.; Falcone, A.; Farnese, C.; Fava, A.; Fichera, F.; Franciotti, D.; Galet, G.; Gibin, D.; Guglielmi, A.; Guida, R.; Ketchum, W.; Marchini, S.; Menegolli, A.; Meng, G.; Menon, G.; Montanari, C.; Nessi, M.; Nicoletto, M.; Pedrotta, R.; Picchi, P.; Pietropaolo, F.; Rampazzo, G.; Rappoldi, A.; Raselli, G.L.; Rossella, M.; Rubbia, C.; Scaramelli, A.; Sergiampietri, F.; Spanu, M.; Torti, M.; Tortorici, F.; Varanini, F.; Ventura, S.; Vignoli, C.; Zani, A.; Zatti, P.G.

The ICARUS T600, a liquid argon time projection chamber (LAr-TPC) detector mainly devoted to neutrino physics, underwent a major overhauling at CERN in 2016-2017, which included also a new design of the read-out electronics, in view of its operation in Fermilab on the Short Baseline Neutrino (SBN) beam from 2019. The new more compact electronics showed capability of handling more efficiently the signals also in the intermediate Induction 2 wire plane with a significant increase of signal to noise (S/N), allowing for charge measurement also in this view. The new front-end and the analog to digital conversion (ADC) system are presented together with the results of the tests on 50 liters liquid argon TPC performed at CERN with cosmic rays.

Flow and spectra for light fragments from Au+Au collisions in the EOS TPC

International Nuclear Information System (INIS)

Lisa, M.A.

1997-01-01

We study the effects of the collective motion (flow) on distributions and yields of light fragments produced in heavy ion collisions at the Bevalac/SIS energy range. p, d, t, 3 He and α fragments emitted from Au+Au collisions at 0.25 - 1.15 AGeV bombarding energy were measured with the EOS TPC. The TPC has high and seamless acceptance in the forward hemisphere of the CM system, and excellent particle identification for light fragments. Analyses of the sidewards flow, squeeze-out, and radial flow signals are presented as a function of bombarding energy and centrality of the collision. The fragment mass systematics of the flow signals are seen to be consistent with a simple coalescence picture for the light particles studied. A unifying framework for describing many of the systematic features of the different types of flow (e.g. the p T dependence of squeeze-out) in terms of 3 parameters is discussed. Consistent with previous studies, the parameter describing squeeze-out is seen to be most sensitive to the Equation of State within a Quantum Molecular Dynamics (QMD) model. The effect on extracted temperature of various radial flow profiles is discussed. Finally, a preliminary study of light particle yields in terms of the Quantum Statistical Model (QSM) is presented. It is found that the beam energy dependence of the 'chemical' temperature obtained from the yields tracks with the 'kinetic' temperature obtained from the spectral fits, if one accounts for a flow profile. However, discrepancies between different implementations (computer codes) of the QSM must be resolved before drawing final conclusions about agreement. (authors)

Meson and baryon correlation studies using the PEP-TPC/2γ Facility

International Nuclear Information System (INIS)

Ronan, M.T.

1991-03-01

Results on vector meson, and strange and charmed-baryon production are presented for data taken during the period 1982--1986 using the TPC/2γ detector at PEP. Vector mesons (ρ 0 , K * and φ) with 0, 1 and 2 strange quarks are used to obtain redundant measures of strange-quark suppression and of the vector to pseudoscalar ratio in hadronization. Measurements of the production rates of Λ, Ξ - , Ω and Ξ *0 hyperons and for the Λ c and of rapidity correlations between Λ bar Λ pairs provide sensitive tests of baryon production in fragmentation models. In addition, two- and three-particle correlations between like sign pions provide further evidence for the Bose-Einstein effect in e + e - interactions including the relativistic motion of particle sources. 9 refs., 7 figs

Performance of a MICROMEGAS-based TPC in a high-energy neutron beam

Science.gov (United States)

Snyder, L.; Manning, B.; Bowden, N. S.; Bundgaard, J.; Casperson, R. J.; Cebra, D. A.; Classen, T.; Duke, D. L.; Gearhart, J.; Greife, U.; Hagmann, C.; Heffner, M.; Hensle, D.; Higgins, D.; Isenhower, D.; King, J.; Klay, J. L.; Geppert-Kleinrath, V.; Loveland, W.; Magee, J. A.; Mendenhall, M. P.; Sangiorgio, S.; Seilhan, B.; Schmitt, K. T.; Tovesson, F.; Towell, R. S.; Walsh, N.; Watson, S.; Yao, L.; Younes, W.

2018-02-01

The MICROMEGAS (MICRO-MEsh GAseous Structure) charge amplification structure has found wide use in many detection applications, especially as a gain stage for the charge readout of Time Projection Chambers (TPCs). Here we report on the behavior of a MICROMEGAS TPC when operated in a high-energy (up to 800 MeV) neutron beam. It is found that neutron-induced reactions can cause discharges in some drift gas mixtures that are stable in the absence of the neutron beam. The discharges result from recoil ions close to the MICROMEGAS that deposit high specific ionization density and have a limited diffusion time. For a binary drift gas, increasing the percentage of the molecular component (quench gas) relative to the noble component and operating at lower pressures generally improves stability.

Design of the cryogenic systems for the Near and Far LAr-TPC detectors of the Short-Baseline Neutrino program (SBN) at Fermilab

CERN Document Server

Geynisman, M; Chalifour, M; Delaney, M; Dinnon, M; Doubnik, R; Hentschel, S; Kim, M J; Montanari, C; Montanari, D; Nichols, T; Norris, B; Sarychev, M; Schwartz, F; Tillman, J; Zuckerbrot, M

2017-01-01

The Short-Baseline Neutrino (SBN) physics program at Fermilab and Neutrino Platform (NP) at CERN are part of the international Neutrino Program leading to the development of Long-Baseline Neutrino Facility/Deep Underground Neutrino Experiment (LBNF/DUNE) science project. The SBN program consisting of three Liquid Argon Time Projection Chamber (LAr-TPC) detectors positioned along the Booster Neutrino Beam (BNB) at Fermilab includes an existing detector known as MicroBooNE (170-ton LAr-TPC) plus two new experiments known as SBN’s Near Detector (SBND, ~260 tons) and SBN’s Far Detector (SBN-FD, ~760 tons). All three detectors have distinctly different design of their cryostats thus defining specific requirements for the cryogenic systems. Fermilab has already built two new facilities to house SBND and SBN-FD detectors. The cryogenic systems for these detectors are in various stages of design and construction with CERN and Fermilab being responsible for delivery of specific sub-systems. This contribution prese...

Tracking Advanced Planetary Systems (TAPAS) with HARPS-N. V. A Massive Jupiter orbiting the very-low-metallicity giant star BD+03 2562 and a possible planet around HD 103485

Science.gov (United States)

Villaver, E.; Niedzielski, A.; Wolszczan, A.; Nowak, G.; Kowalik, K.; Adamów, M.; Maciejewski, G.; Deka-Szymankiewicz, B.; Maldonado, J.

2017-10-01

Context. Evolved stars with planets are crucial to understanding the dependency of the planet formation mechanism on the mass and metallicity of the parent star and to studying star-planet interactions. Aims: We present two evolved stars (HD 103485 and BD+03 2562) from the Tracking Advanced PlAnetary Systems (TAPAS) with HARPS-N project devoted to RV precision measurements of identified candidates within the PennState - Toruń Centre for Astronomy Planet Search. Methods: The paper is based on precise radial velocity (RV) measurements. For HD 103485 we collected 57 epochs over 3317 days with the Hobby-Eberly Telescope (HET) and its high-resolution spectrograph and 18 ultra-precise HARPS-N data over 919 days. For BD+03 2562 we collected 46 epochs of HET data over 3380 days and 19 epochs of HARPS-N data over 919 days. Results: We present the analysis of the data and the search for correlations between the RV signal and stellar activity, stellar rotation, and photometric variability. Based on the available data, we interpret the RV variations measured in both stars as Keplerian motion. Both stars have masses close to Solar (1.11 M⊙ HD 103485 and 1.14 M⊙ BD+03 2562), very low metallicities ([Fe/H] = - 0.50 and - 0.71 for HD 103485 and BD+03 2562), and both have Jupiter planetary mass companions (m2sini = 7 and 6.4 MJ for HD 103485 and BD+03 2562 resp.) in close to terrestrial orbits (1.4 au HD 103485 and 1.3 au BD+03 2562) with moderate eccentricities (e = 0.34 and 0.2 for HD 103485 and BD+03 2562). However, we cannot totally rule-out the possibility that the signal in the case of HD 103485 is due to rotational modulation of active regions. Conclusions: Based on the current data, we conclude that BD+03 2562 has a bona fide planetary companion while for HD 103485 we cannot totally exclude the possibility that the best explanation for the RV signal modulations is not the existence of a planet but stellar activity. If the interpretation remains that both stars have

Neutron fluence and energy reconstruction with the IRSN recoil detector μ-TPC at 27 keV, 144 keV and 565 keV

Energy Technology Data Exchange (ETDEWEB)

Maire, D.; Lebreton, L.; Richer, J.P. [IRSN, PRP-HOM, SDE, LMDN, 13115 Saint Paul-Lez-Durance (France); Bosson, G.; Bourrion, O.; Guillaudin, O.; Riffard, Q.; Santos, D. [CNRS/IN2P3-UJF-INPG, LPSC, 38000 Grenoble (France)

2015-07-01

The French Institute for Radioprotection and Nuclear Safety (IRSN), associated to the French Metrology Institute (LNE), is developing a time projection chamber using a Micromegas anode: μ-TPC. This work is carried out in collaboration with the Laboratory of Subatomic Physics and Cosmology (LPSC). The aim is to characterize with a primary procedure the energy distribution of neutron fluence in the energy range 8 keV - 1 MeV. The time projection chambers are gaseous detectors, which are able to measure charged particles energy and to reconstruct their track if a pixelated anode is used. In our case, the gas is used as a (n, p) converter in order to detect neutrons down to few keV. Coming from elastic collisions with neutrons, recoil protons lose a part of their kinetic energy by ionizing the gas. The ionization electrons are drifted toward a pixelated anode (2D projection), read at 50 MHz by a self-triggered electronic system to obtain the third track dimension. The neutron energy is reconstructed event by event thanks to proton scattering angle and proton energy measurements. The scattering angle is deduced from the 3D track. The proton energy is obtained by charge collection measurements, knowing the ionization quenching factor (i.e. the part of proton kinetic energy lost by ionizing the gas). The fluence is calculated thanks to the detected events number and the simulated detector response. The μ-TPC is a new reliable detector which enables to measure energy distribution of the neutron fluence without deconvolution or neutron calibration contrary to usual gaseous counters. The μ-TPC is still being developed and measurements have been carried out at the AMANDE facility, with neutrons energies going from 8 keV to 565 keV. After the context and the μ-TPC working principle presentation, measurements of the neutron energy and fluence at 27.2 keV, 144 keV and 565 keV are shown and compared to the complete detector simulation. This work shows the first direct

Observation and applications of single-electron charge signals in the XENON100 experiment

NARCIS (Netherlands)

Aprile, E.; et al., [Unknown; Alfonsi, M.; Colijn, A.P.; Decowski, M.P.

2014-01-01

The XENON100 dark matter experiment uses liquid xenon in a time projection chamber (TPC) to measure xenon nuclear recoils resulting from the scattering of dark matter weakly interacting massive particles (WIMPs). In this paper, we report the observation of single-electron charge signals which are

Quality assurance of GEM foils in the framework of the TPC upgrade in the ALICE experiment

CERN Document Server

Ozcelik, Melih Arslan

2016-01-01

In the framework of the TPC upgrade of the ALICE Experiment, new readout chambers will be installed during the LHC long shutdown 2, which is scheduled to start in July 2018. The current MWPCs (Multi Wire Proportional Chambers) will be replaced by readout chambers consisting of GEM (Gas Electron Multipliers) foils in order to meet the increasing readout rate requirements. QA (Quality Assurance) tests on the GEMs are performed to classify the foils. In this report we present the work done during the CERN Summer Student Programme 2016.

MSD与TPC技术调频遥测方法研究%Research on PCM-FM Technology Based on MSD and TPC

Institute of Scientific and Technical Information of China (English)

闫冬; 孙晓锋; 孙大元

2016-01-01

调频信号具有很好的抗航天器飞行尾焰干扰能力。在同信噪比下，调频信号解调误码率高于调相信号，所以调频信号解调需要提高增益。多符号检测（ MSD）和Turbo乘积（ TPC）编码的联合算法可以提高调频信号的增益。介绍了MSD和TPC编码的联合算法和设计结构，根据仿真结果对比了差分解调、 MSD解调、 MSD与TPC编码的联合算法在各种信噪比下的性能指标，证明了该联合算法提高了近7 dB的增益。%The PCM⁃FM signal has better anti⁃interference capability for aerospace⁃craft jetting out the flame.In the same signal⁃noise ratio,the BER of PCM⁃FM signal demodulation is higher than that of phase modulated signal,so it is required to improve the gain of PCM⁃FM signal demodulation.The joint algorithm of multi⁃signal detection (MSD) and Turbo product coding (TPC) can improve the gain of PCM⁃FM signal.This paper introduces the joint algorithm of MSD and TPC coding and design structure.The performance index of differential demodulation,MSD demodulation,as well as MSD and TPC coding joint algoritm are compared in various signal⁃noise ratios, and the results show this joint algorithm can increase the gain of 7 dB.

arXiv Particle identification studies with a full-size 4-GEM prototype for the ALICE TPC upgrade

CERN Document Server

INSPIRE-00180720; Aiola, S.; Alme, J.; Alt, T.; Amend, W.; Andronic, A.; Anguelov, V.; Appelshäuser, H.; Arslandok, M.; Averbeck, R.; Ball, M.; Barnaföldi, G.G.; Bartsch, E.; Bellwied, R.; Bencedi, G.; Berger, M.; Bialas, N.; Bialas, P.; Bianchi, L.; Biswas, S.; Boldizsár, L.; Bratrud, L.; Braun-Munzinger, P.; Bregant, M.; Britton, C.L.; Brucken, E.J.; Caines, H.; Castro, A.J.; Chattopadhyay, S.; Christiansen, P.; Clonts, L.G.; Cormier, T.M.; Das, S.; Dash, S.; Deisting, A.; Dittrich, S.; Dubey, A.K.; Ehlers, R.; Erhardt, F.; Ezell, N.B.; Fabbietti, L.; Frankenfeld, U.; Gaardhøje, J.J.; Garabatos, C.; Gasik, P.; Gera, A.; Ghosh, P.; Ghosh, S.K.; Glässel, P.; Grachov, O.; Grein, A.; Gunji, T.; Hamagaki, H.; Hamar, G.; Harris, J.W.; Hehner, J.; Hellbär, E.; Helstrup, H.; Hilden, T.E.; Hohlweger, B.; Ivanov, M.; Jung, M.; Just, D.; Kangasaho, E.; Keidel, R.; Ketzer, B.; Khan, S.A.; Kirsch, S.; Klemenz, T.; Klewin, S.; Knospe, A.G.; Kowalski, M.; Kumar, L.; Lang, R.; Langoy, R.; Lautner, L.; Liebske, F.; Lien, J.; Lippmann, C.; Ljunggren, H.M.; Llope, W.J.; Mahmood, S.; Mahmoud, T.; Majka, R.; Malzacher, P.; Marín, A.; Markert, C.; Masciocchi, S.; Mathis, A.; Matyja, A.; Meres, M.; Mihaylov, D.L.; Miskowiec, D.; Mitra, J.; Mittelstaedt, T.; Morhardt, T.; Mulligan, J.; Munzer, R.H.; Münning, K.; Munhoz, M.G.; Muhuri, S.; Murakami, H.; Nandi, B.K.; Natal da Luz, H.; Nattrass, C.; Nayak, T.K.; Negrao De Oliveira, R.A.; Nicassio, M.; Nielsen, B.S.; Oláh, L.; Oskarsson, A.; Otwinowski, J.; Oyama, K.; Paić, G.; Patra, R.N.; Peskov, V.; Pikna, M.; Pinsky, L.; Planinic, M.; Poghosyan, M.G.; Poljak, N.; Pompei, F.; Prasad, S.K.; Pruneau, C.A.; Putschke, J.; Raha, S.; Rak, J.; Rasson, J.; Ratza, V.; Read, K.F.; Rehman, A.; Renfordt, R.; Richert, T.; Røed, K.; Röhrich, D.; Rudzki, T.; Sahoo, R.; Sahoo, S.; Sahu, P.K.; Saini, J.; Schaefer, B.; Schambach, J.; Scheid, S.; Schmidt, C.; Schmidt, H.R.; V Schmidt, N.; Schulte, H.; Schweda, K.; Selyuzhenkov, I.; Sharma, N.; Silvermyr, D.; Singaraju, R.N.; Sitar, B.; Smirnov, N.; Sorensen, S.P.; Sozzi, F.; Stachel, J.; Stenlund, E.; Strmen, P.; Szarka, I.; Tambave, G.; Terasaki, K.; Timmins, A.; Ullaland, K.; Utrobicic, A.; Varga, D.; Varma, R.; Velure, A.; Vislavicius, V.; Voloshin, S.; Voss, B.; Vranic, D.; Wiechula, J.; Winkler, S.; Wikne, J.; Windelband, B.; Zhao, C.

A large Time Projection Chamber is the main device for tracking and charged-particle identification in the ALICE experiment at the CERN LHC. After the second long shutdown in 2019/20, the LHC will deliver Pb beams colliding at an interaction rate of about 50 kHz, which is about a factor of 50 above the present readout rate of the TPC. This will result in a significant improvement on the sensitivity to rare probes that are considered key observables to characterize the QCD matter created in such collisions. In order to make full use of this luminosity, the currently used gated Multi-Wire Proportional Chambers will be replaced. The upgrade relies on continuously operated readout detectors employing Gas Electron Multiplier technology to retain the performance in terms of particle identification via the measurement of the specific energy loss by ionization d$E$/d$x$. A full-size readout chamber prototype was assembled in 2014 featuring a stack of four GEM foils as an amplification stage. The performance of the pr...

VizieR Online Data Catalog: Li abundances in F stars (Delgado Mena+, 2015)

Science.gov (United States)

Delgado Mena, E.; Bertran de Lis, S.; Adibekyan, V. Z.; Sousa, S. G.; Figueira, P.; Mortier, A.; Gonzalez Hernandez, J. I.; Tsantaki, M.; Israelian, G.; Santos, N. C.

2015-06-01

Our baseline sample is 1111 FGK stars observed within the context of the HARPS GTO programs. It is a combination of three HARPS subsamples hereafter called HARPS-1 (Mayor et al., 2003Msngr.114...20M), HARPS-2 (Lo Curto et al., 2010, Cat. J/A+A/512/A48), and HARPS-4 (Santos et al., 2011, Cat. J/A+A/526/A112). The individual spectra of each star were reduced using the HARPS pipeline and then combined with IRAF2 after correcting for its radial velocity shift. The final spectra have a resolution of R~110000 and high signal-to-noise ratio (55% of the spectra have a S/N higher than 200). The total sample is composed of 135 stars with planets and 976 stars without detected planets. (4 data files).

Energy calibration of a GEM-TPC with Kr83m

Energy Technology Data Exchange (ETDEWEB)

Schmitz, Roman [Helmholtz-Institut fuer Strahlen- und Kernphysik, Universitaet Bonn (Germany); Collaboration: GEM-TPC-Collaboration

2013-07-01

A Time Projection Chamber (TPC) with Gas Electron Multiplier (GEM) readout has been developed with an inner/outer radius of 5/15 cm and a total drift length of 73 cm. It has been used as an inner tracking upgrade for the FOPI experiment at GSI and is planned as a future upgrade to the CBELSA/TAPS experiment. A radioactive {sup 83m}Kr source has been produced and integrated into the setup in order to perform an accurate channel-wise relative gain calibration and monitor gain stability to achieve optimal dE/dx resolution. Its gaseous form makes it perfectly suitable for this purpose allowing a full coverage of the readout plane and providing a wide energy range of conversion peaks. Also its half-life of 1.83 h allows for normal detector operation after a short flushing period of several hours. Calibration method and measured energy resolution for different gas mixtures which have been compared to simulation results are presented in this talk. Also first results on gain stability and pressure/temperature-dependence are shown.

Tracking Advanced Planetary Systems (TAPAS) with HARPS-N. VI. HD 238914 and TYC 3318-01333-1: two more Li-rich giants with planets

Science.gov (United States)

Adamów, M.; Niedzielski, A.; Kowalik, K.; Villaver, E.; Wolszczan, A.; Maciejewski, G.; Gromadzki, M.

2018-05-01

Context. We present the latest results of our search for planets with HARPS-N at the 3.6 m Telescopio Nazionale Galileo under the Tracking Advanced Planetary Systems project: an in-depth study of the 15 most Li abundant giants from the PennState - Toruń Planet Search sample. Aims: Our goals are first, to obtain radial velocities of the most Li-rich giants we identified in our sample to search for possible low-mass substellar companions, and second, to perform an extended spectral analysis to define the evolutionary status of these stars. Methods: This work is based on high-resolution spectra obtained with the Hobby-Eberly Telescope and its High Resolution Spectrograph, and with the HARPS-N spectrograph at the Telescopio Nazionale Galileo. Two stars, HD 181368 and HD 188214, were also observed with UVES at the VLT to determine beryllium abundances. Results: We report i) the discovery of two new planetary systems around the Li-rich giant stars: HD 238914 and TYC 3318-01333-1 (a binary system); ii) reveal a binary Li-rich giant, HD 181368; iii) although our current phase coverage is not complete, we suggest the presence of planetary mass companions around TYC 3663-01966-1 and TYC 3105-00152-1; iv) we confirm the previous result for BD+48 740 and present updated orbital parameters, and v) we find a lack of a relation between the Li enhancement and the Be abundance for the stars HD 181368 and HD 188214, for which we acquired blue spectra. Conclusions: We found seven stars with stellar or potential planetary companions among the 15 Li-rich giant stars. The binary star frequency of the Li-rich giants in our sample appears to be normal, but the planet frequency is twice that of the general sample, which suggests a possible connection between hosting a companion and enhanced Li abundance in giant stars. We also found most of the companions orbits to be highly eccentric. Based on observations obtained with the Hobby-Eberly Telescope, which is a joint project of the

Measurements of electron drift and diffusion properties in a large cylindrical drift chamber (TPC) with parallel electric and magnetic fields

International Nuclear Information System (INIS)

Richstein, J.

1986-01-01

This work describes measurements on the drift of electrons in gases, using the TPC90, the prototype of the ALEPH Time Projection Chamber. Tracks which were created by UV-Laser ionization have been drifted over distances of up to 1.3 m in parallel electric and magnetic fields. Electron drift properties have been systematically measured as a function of these, in several gas mixtures. (orig./HSI)

Design of the cryogenic systems for the Near and Far LAr-TPC detectors of the Short-Baseline Neutrino program (SBN) at Fermilab

Energy Technology Data Exchange (ETDEWEB)

Geynisman, M. [Fermilab; Bremer, J. [CERN; Chalifour, M. [CERN; Delaney, M. [Fermilab; Dinnon, M. [Fermilab; Doubnik, R. [Fermilab; Hentschel, S. [Fermilab; Kim, M. J. [Fermilab; Montanari, C. [INFN, Pavia; Monatanari, D. [Fermilab; Nichols, T. [Fermilab; Norris, B. [Fermilab; Sarychev, M. [Fermilab; Schwartz, F. [Fermilab; Tillman, J. [Fermilab; Zuckerbrot, M. [Fermilab

2017-08-31

The Short-Baseline Neutrino (SBN) physics program at Fermilab and Neutrino Platform (NP) at CERN are part of the international Neutrino Program leading to the development of Long-Baseline Neutrino Facility/Deep Underground Neutrino Experiment (LBNF/DUNE) science project. The SBN program consisting of three Liquid Argon Time Projection Chamber (LAr-TPC) detectors positioned along the Booster Neutrino Beam (BNB) at Fermilab includes an existing detector known as MicroBooNE (170-ton LAr-TPC) plus two new experiments known as SBN’s Near Detector (SBND, ~260 tons) and SBN’s Far Detector (SBN-FD, ~760 tons). All three detectors have distinctly different design of their cryostats thus defining specific requirements for the cryogenic systems. Fermilab has already built two new facilities to house SBND and SBN-FD detectors. The cryogenic systems for these detectors are in various stages of design and construction with CERN and Fermilab being responsible for delivery of specific sub-systems. This contribution presents specific design requirements and typical implementation solutions for each sub-system of the SBND and SBN-FD cryogenic systems.

Electroluminescence pulse shape and electron diffusion in liquid argon measured in a dual-phase TPC

Energy Technology Data Exchange (ETDEWEB)

Agnes, P.; et al.

2018-02-05

We report the measurement of the longitudinal diffusion constant in liquid argon with the DarkSide-50 dual-phase time projection chamber. The measurement is performed at drift electric fields of 100 V/cm, 150 V/cm, and 200 V/cm using high statistics $^{39}$Ar decays from atmospheric argon. We derive an expression to describe the pulse shape of the electroluminescence signal (S2) in dual-phase TPCs. The derived S2 pulse shape is fit to events from the uppermost portion of the TPC in order to characterize the radial dependence of the signal. The results are provided as inputs to the measurement of the longitudinal diffusion constant DL, which we find to be (4.12 $\\pm$ 0.04) cm$^2$/s for a selection of 140keV electron recoil events in 200V/cm drift field and 2.8kV/cm extraction field. To study the systematics of our measurement we examine datasets of varying event energy, field strength, and detector volume yielding a weighted average value for the diffusion constant of (4.09 $\\pm$ 0.09) cm$^2$ /s. The measured longitudinal diffusion constant is observed to have an energy dependence, and within the studied energy range the result is systematically lower than other results in the literature.

μ-TPC: a future standard instrument for low energy neutron field characterization

International Nuclear Information System (INIS)

Maire, D.; Lebreton, L.; Petit, M.; Billard, J.; Bourrion, O.; Bosson, G.; Guillaudin, O.; Lamblin, J.; Mayet, F.; Medard, J.; Muraz, J.F.; Richer, J.P.; Riffard, Q.; Santos, D.

2013-06-01

In order to measure energy of neutron fields, with energy ranging from 8 keV to 1 MeV, a new primary standard is being developed at the IRSN (Institute for Radioprotection and Nuclear Safety). This project, μ-TPC (Micro Time Projection Chamber), carried out in collaboration with the LPSC (Laboratoire de Physique Subatomique et de Cosmologie), is based on the nucleus recoil detector principle. The instrument will be presented with the associated method to measure the neutron energy. This article will emphasize the proton energy calibration procedure and energy measurements of a neutron field produced at 127 keV on the IRSN facility AMANDE. Finally the COMIMAC device, dedicated to the calibration, will be described. This original device, developed at the LPSC, is able to produce proton and electron beams with an accurate energy ranging from 1 keV to 50 keV. (authors)

HD 89345: a bright oscillating star hosting a transiting warm Saturn-sized planet observed by K2

Science.gov (United States)

Van Eylen, V.; Dai, F.; Mathur, S.; Gandolfi, D.; Albrecht, S.; Fridlund, M.; García, R. A.; Guenther, E.; Hjorth, M.; Justesen, A. B.; Livingston, J.; Lund, M. N.; Pérez Hernández, F.; Prieto-Arranz, J.; Regulo, C.; Bugnet, L.; Everett, M. E.; Hirano, T.; Nespral, D.; Nowak, G.; Palle, E.; Silva Aguirre, V.; Trifonov, T.; Winn, J. N.; Barragán, O.; Beck, P. G.; Chaplin, W. J.; Cochran, W. D.; Csizmadia, S.; Deeg, H.; Endl, M.; Heeren, P.; Grziwa, S.; Hatzes, A. P.; Hidalgo, D.; Korth, J.; Mathis, S.; Montañes Rodriguez, P.; Narita, N.; Patzold, M.; Persson, C. M.; Rodler, F.; Smith, A. M. S.

2018-05-01

We report the discovery and characterization of HD 89345b (K2-234b; EPIC 248777106b), a Saturn-sized planet orbiting a slightly evolved star. HD 89345 is a bright star (V = 9.3 mag) observed by the K2 mission with one-minute time sampling. It exhibits solar-like oscillations. We conducted asteroseismology to determine the parameters of the star, finding the mass and radius to be 1.12^{+0.04}_{-0.01} M_⊙ and 1.657^{+0.020}_{-0.004} R_⊙, respectively. The star appears to have recently left the main sequence, based on the inferred age, 9.4^{+0.4}_{-1.3} Gyr, and the non-detection of mixed modes. The star hosts a "warm Saturn" (P = 11.8 days, Rp = 6.86 ± 0.14 R⊕). Radial-velocity follow-up observations performed with the FIES, HARPS, and HARPS-N spectrographs show that the planet has a mass of 35.7 ± 3.3 M⊕. The data also show that the planet's orbit is eccentric (e ≈ 0.2). An investigation of the rotational splitting of the oscillation frequencies of the star yields no conclusive evidence on the stellar inclination angle. We further obtained Rossiter-McLaughlin observations, which result in a broad posterior of the stellar obliquity. The planet seems to conform to the same patterns that have been observed for other sub-Saturns regarding planet mass and multiplicity, orbital eccentricity, and stellar metallicity.

Search for QGP signals at AGS with a TPC spectrometer, and comparison of our event generator predictions for plasma model and cascade interactions

International Nuclear Information System (INIS)

Lindenbaum, S.J.; Foley, K.J.; Eiseman, S.E.

1988-01-01

We have developed and successfully tested a TPC Magnetic Spectrometer to search for QGP signals produced by ion beams at AGS. We also developed a cascade and plasma event generator the predictions of which are used to illustrate how our technique can detect possible plasma signals. 4 refs., 6 figs., 1 tab

Characteristics of triple GEM detector for the ALICE TPC upgrade at CERN

International Nuclear Information System (INIS)

Patra, Rajendra Nath; Singaraju, R.N.; Ahammed, Z.; Nayak, T.K.; Viyogi, Y.P.; Biswas, S.

2016-01-01

Gas Electron Multiplier (GEM) detector, introduced by F. Sauliin 1997 and has been widely improved in last two decades for applications to high energy physics experiments and imaging. GEM detectors have several advantages, like good spatial resolution (∼100 μm), high detection efficiency (>98%), high rate handling capability (∼105 Hz/mm"2 ) and reasonable time response (∼5 ns). The unique features of the GEM detector make it suitable for experiments at Large Hadron Collider (LHC) at CERN and FAIR at GSI. With the increase of beam luminosity of LHC for its next phase of running from the year 2020, the ALICE experiment is planning to take data for PbPb collisions at a rate of 50 kHz. The ALICE Time Projection Chamber (TPC) will be upgraded by GEM based read-out to fulfil this future goal. In this report, results of a thorough test in the laboratory using a newly developed online data monitoring system are discussed

Electron Attenuation Measurement using Cosmic Ray Muons at the MicroBooNE LArTPC

Energy Technology Data Exchange (ETDEWEB)

Meddage, Varuna [Kansas State U., Manhattan

2017-10-01

The MicroBooNE experiment at Fermilab uses liquid argon time projection chamber (LArTPC) technology to study neutrino interactions in argon. A fundamental requirement for LArTPCs is to achieve and maintain a low level of electronegative contaminants in the liquid to minimize the capture of drifting ionization electrons. The attenuation time for the drifting electrons should be long compared to the maximum drift time, so that the signals from particle tracks that generate ionization electrons with long drift paths can be detected efficiently. In this talk we present MicroBooNE measurement of electron attenuation using cosmic ray muons. The result yields a minimum electron 1/e lifetime of 18 ms under typical operating conditions, which is long compared to the maximum drift time of 2.3 ms.

Heavy-ion test of detectors with conventional and resistive Micromegas used in TPC configuration

Energy Technology Data Exchange (ETDEWEB)

Ducret, Jean-Eric, E-mail: jean-eric.ducret@cea.f [Commissariat a l' Energie Atomique, IRFU, F91191 Gif sur Yvette (France); Legou, Philippe [Commissariat a l' Energie Atomique, IRFU, F91191 Gif sur Yvette (France); Lukasik, Jerzy [Institute of Nuclear Physics, IFJ-PAN, ul. Radzikowskiego 152, 31-342 Krakow (Poland); Boudard, Alain; Combet, Michel [Commissariat a l' Energie Atomique, IRFU, F91191 Gif sur Yvette (France); Czech, BronisLaw [Institute of Nuclear Physics, IFJ-PAN, ul. Radzikowskiego 152, 31-342 Krakow (Poland); Durand, Robert; Gorbinet, Thomas; Le Bourlout, Pascal; Leray, Sylvie [Commissariat a l' Energie Atomique, IRFU, F91191 Gif sur Yvette (France); Matousek, Vladislav [Institute of Physics, Slovak Academy of Sciences, Dubravska cesta 9, 854 11 Bratislava (Slovakia); Nizery, Francois [Commissariat a l' Energie Atomique, IRFU, F91191 Gif sur Yvette (France); PawLowski, Piotr [Institute of Nuclear Physics, IFJ-PAN, ul. Radzikowskiego 152, 31-342 Krakow (Poland); Salsac, Marie-Delphine [Commissariat a l' Energie Atomique, IRFU, F91191 Gif sur Yvette (France); Yordanov, Orlin [Institute of Nuclear Research and Nuclear Energy, Bulgarian Academy of Sciences, 72, Tzanigradsko chaussee Blvd, BG-1784 Sofia (Bulgaria)

2011-02-01

We have performed tests of Micromegas detector prototypes using the heavy-ion beams from the SIS synchrotron of GSI (Darmstadt, Germany). The beams varied from {sup 12}C{sup 6+} to {sup 179}Au{sup 65+} and from 250 to 1000 MeV per nucleon. We have tested two amplification technologies, conventional and resistive Micromegas, and two construction concepts, bulk-Micromegas and micro-meshes screwed on the PCB. The obtained position resolution below 200{mu}m for 5 mm wide strips implies that the bulk resistive Micromegas technology might meet the requirements of the future R3B TPC project. We also developed a fast and very low noise front-end electronics connected directly to the Printed Circuit Board (PCB) of the detector itself. This concept has shown very good performances and robustness.

Firmware Development and Integration for ALICE TPC and PHOS Front-end Electronics A Trigger Based Readout and Control System operating in a Radiation Environment

CERN Document Server

AUTHOR|(CDS)2068589; Rohrich, Dieter

2008-01-01

The readout electronics in PHOS and TPC - two of the major detectors of the ALICE experiment at the LHC - consist of a set of Front End Cards (FECs) that digitize, process and buffer the data from the detector sensors. The FECs are connected to a Readout Control Unit (RCU) via two sets of custom made PCB backplanes. For PHOS, 28 FECs are connected to one RCU, while for TPC the number is varying from 18 to 25 FECs depending on location. The RCU is in charge of the data readout, including reception and distribution of triggers and in moving the data from the FECs to the Data Acquisition System. In addition it does low level control tasks. The RCU consists of an RCU Motherboard that hosts a Detector Control System (DCS) board and a Source Interface Unit. The DCS board is an embedded computer running Linux that controls the readout electronics. All the mentioned devices are implemented in commercial grade SRAM based Field Programmable Gate Arrays (FPGAs). Even if these devices are not very radiation tolerant, the...

Family members' views on the benefits of harp music vigils for terminally-ill or dying loved ones.

Science.gov (United States)

Ganzini, Linda; Rakoski, Alexa; Cohn, Sharilyn; Mularski, Richard A

2015-02-01

Music-thanatology is a palliative modality that uses harp and voice to provide bedside vigils, particularly for terminally ill or actively dying. We sought to determine the benefits of music vigils for terminally ill patients. Survey of 55 family members, whose terminally ill loved one experienced a music vigil during hospitalization, regarding effects on the patient's breathing, relaxation, comfort, pain and ability to sleep. Written comments on negative and positive results of the vigils were coded using content analysis. Family members perceived that the vigils resulted in modest improvement in the patients' breathing, relaxation, comfort, and ability to sleep, with fewer positive effects on pain, and almost no negative effects. Open ended comments focused on the positive benefit in increasing calm, relaxation, comfort. Comments on the positive effects for the family were almost as common as comments on the positive results for the patient. The use of music-vigils in palliative care should be investigated more extensively as our study supports that this intervention has benefits, almost no risk, minimal cost, and may improve patient-family experience of the dying process.

Drift velocity studies at a time projection chamber for various water contents in the gas mixture; Driftgeschwindigkeitsstudien an einer Zeit-Projektions-Kammer (TPC) bei unterschiedlichen Wassergehalten des Kammergases

Energy Technology Data Exchange (ETDEWEB)

Stoever, F.W.

2007-03-15

For the answer of different open questions in high energy physics the construction of a linear e{sup +}e{sup -} collider with a c. m. energy of up to one TeV is prepared. With this is connected a comprehensive development on detectors, which must satisfy the requirements of the planned experiments. For the track chamber a TPC is considered. Hereby it deals with a gas-based concept, which has already been proved in past experiments and which is at time further developed by means of test chambers. The composition of the gas mixtureplays hereby an important role. Impurities of the gas mixture, especially by oxygen and water from the ambient air are a fact, which occurs every time in the development phase and can scarcely be avoided. From this arose the motivation to study directly the effects of this impurities. The object of the present thesis are correlations between drift velocity and water content in the chamber gas of a TPC.

Seasonal changes in background levels of deuterium and oxygen-18 prove water drinking by harp seals, which affects the use of the doubly labelled water method.

Science.gov (United States)

Nordøy, Erling S; Lager, Anne R; Schots, Pauke C

2017-12-01

The aim of this study was to monitor seasonal changes in stable isotopes of pool freshwater and harp seal ( Phoca groenlandica ) body water, and to study whether these potential seasonal changes might bias results obtained using the doubly labelled water (DLW) method when measuring energy expenditure in animals with access to freshwater. Seasonal changes in the background levels of deuterium and oxygen-18 in the body water of four captive harp seals and in the freshwater pool in which they were kept were measured over a time period of 1 year. The seals were offered daily amounts of capelin and kept under a seasonal photoperiod of 69°N. Large seasonal variations of deuterium and oxygen-18 in the pool water were measured, and the isotope abundance in the body water showed similar seasonal changes to the pool water. This shows that the seals were continuously equilibrating with the surrounding water as a result of significant daily water drinking. Variations in background levels of deuterium and oxygen-18 in freshwater sources may be due to seasonal changes in physical processes such as precipitation and evaporation that cause fractionation of isotopes. Rapid and abrupt changes in the background levels of deuterium and oxygen-18 may complicate calculation of energy expenditure by use of the DLW method. It is therefore strongly recommended that analysis of seasonal changes in background levels of isotopes is performed before the DLW method is applied on (free-ranging) animals, and to use a control group in order to correct for changes in background levels. © 2017. Published by The Company of Biologists Ltd.

VizieR Online Data Catalog: Chemical abundances of 1059 FGK stars (Delgado Mena+, 2017)

Science.gov (United States)

Delgado Mena, E.; Tsantaki, M.; Adibekyan, V. Zh.; Sousa, S. G.; Santos, N. C.; Gonzalez Hernandez, J. I.; Israelian, G.

2017-07-01

The baseline sample used in this work is formed by 1111 FGK stars observed within the context of the HARPS GTO programs. It is a combination of three HARPS subsamples hereafter called HARPS-1 (Mayor et al., 2003Msngr.114...20M), HARPS-2 (Lo Curto et al., 2010, Cat. J/A+A/512/A48), and HARPS-4 (Santos et al., 2011, Cat. J/A+A/526/A112). The individual spectra of each star were reduced using the HARPS pipeline and then combined with IRAF after correcting for its radial velocity shift. The final spectra have a resolution of R~115000 and high signal-to-noise ratios (55%of the spectra have a S/N higher than 200). The total sample is composed of 136 stars with planets and 975 stars without detected planets. Chemical abundances of these samples for refractory elements with AMena et al., 2014, Cat. J/A+A/562/A92; 2015, Cat. J/A+A/576/A69), and nitrogen abundances (Suarez-Andres et al., 2016A&A...591A..69S, only for a small fraction of stars). (2 data files).

Precision meson spectroscopy. Diffractive production at COMPASS and development of a GEM-based TPC for PANDA

International Nuclear Information System (INIS)

Weitzel, Quirin

2008-01-01

Meson spectroscopy is a unique way to access Quantum Chromo Dynamics (QCD) and learn about its properties. Due to the non-Abelian structure, QCD predicts new states of matter with gluonic degrees of freedom. In particular q anti qg hybrids, which can have spin-exotic quantum numbers forbidden for conventional q anti q mesons, are expected to exist. Such states were searched for in the past, mostly in the light-quark sector. However, the experimental situation is still ambiguous and needs to be clarified. Further insights will certainly also come from the heavy-quark spectroscopy. Several new charmonium-like resonances were for example discovered during the last years, which have to be studied in more detail by future experiments to reveal their nature. Diffractive dissociation reactions at COMPASS provide clean access to meson resonances with masses below 2.5 GeV/c 2 . During a pilot run in 2004 using pion beams on lead targets, a competitive number of π - π - π + final state events were recorded within a few days of data taking. A full partial wave analysis (PWA) of these data has been performed for this dissertation, concentrating on the kinematic domain of large momentum transfer (t' element of [0.1, 1.0] GeV 2 /c 2 ). While well-known mesons are resolved with high quality, also a strong signal consistent with the much disputed hybrid candidate π 1 (1600) is observed in the spin-exotic J PC = 1 -+ partial wave. A Breit-Wigner parameterization yields a mass and width of 1.660 +0.010 -0.074 and 0.269 +0.063 -0.085 GeV/c 2 , respectively. In addition, a first PWA of events with small momentum transfer (t' element of [10 -3 ,10 -2 ] GeV 2 /c 2 ) has been carried out, yielding several high-mass radial-excitation states. In the future, the PANDA experiment at the FAIR facility will perform highprecision spectroscopy in the charm-sector employing anti pp annihilations. Due to its excellent tracking capabilities for charged particles, a time projection chamber (TPC

LBNO-DEMO (WA105): a large demonstrator of the Liquid Argon double phase TPC

CERN Document Server

Trzaska, Wladyslaw Henryk

2015-01-01

LBNO-DEMO (WA105) is a large demonstrator of the double phase liquid argon TPC intended to develop and test the main elements of the GLACIER-based design for the purpose of scaling it up to the 10–50 kton size needed for Long Baseline Neutrino Oscillation studies. The crucial components of the design are: ultra-high argon purity in non-evacuable tank, long drifts, very high drift voltages, large area Micro Pattern Gas Detectors, and cold preamplifiers. The active volume of the demonstrator is 666 m3 (approximately 300t). WA105 is under construction at CERN and will be exposed to charged particle beams (0.5-20 GeV/c) in the North Area in 2018. The data will provide the necessary calibration of the detector performance and benchmark reconstruction algorithms. This project is a crucial milestone for the long baseline neutrino program, including projects like LBNO and DUNE.

The $\\mu$TPC Method: Improving the Position Resolution of Neutron Detectors Based on MPGDs

CERN Document Server

Pfeiffer, Dorothea; Birch, Jens; Hall-Wilton, Richard; Höglund, Carina; Hultman, Lars; Iakovidis, George; Oliveri, Eraldo; Oksanen, Esko; Ropelewski, Leszek; Thuiner, Patrik

2015-01-01

Due to the Helium-3 crisis, alternatives to the standard neutron detection techniques are becoming urgent. In addition, the instruments of the European Spallation Source (ESS) require advances in the state of the art of neutron detection. The instruments need detectors with excellent neutron detection efficiency, high-rate capabilities and unprecedented spatial resolution. The Macromolecular Crystallography instrument (NMX) requires a position resolution in the order of 200 um over a wide angular range of incoming neutrons. Solid converters in combination with Micro Pattern Gaseous Detectors (MPGDs) are proposed to meet the new requirements. Charged particles rising from the neutron capture have usually ranges larger than several millimetres in gas. This is apparently in contrast with the requirements for the position resolution. In this paper, we present an analysis technique, new in the field of neutron detection, based on the Time Projection Chamber (TPC) concept. Using a standard Single-GEM with the catho...

For high energy heavy ion experiments TPC 4π detector 'Diogene'. What possibilities and what physics

International Nuclear Information System (INIS)

Babinet, R.; Cassagnou, Y.; Drouet, M.

1981-05-01

'Diogene' is the name of a 4π solid angle detector, based on a Time Projection Chamber (TPC), designed to perform exclusive measurements of charged particles emitted in central collisions of relativistic heavy ions. Exclusive measurements of all charged particles emitted in central collisions of relativistic heavy ions are becoming more and more necessary in this field of nuclear physics in order to answer some crucial questions such as: what is the degree of compression achieved in these collisions. What is the behavior of nuclear matter at high degree of excitation as well as compression. The possibility of handling high multiplicities up to 40 or 60; a momentum measurement of all particles, with not too bad a resolution, up to about 1.5 GeV/c; a good particle identification between π +- , p, d, t ..

A Prototype Combination TPC Cherenkov Detector with GEM Readout for Tracking and Particle Identification and its Potential Use at an Electron Ion Collider

Directory of Open Access Journals (Sweden)

Woody Craig

2018-01-01

Full Text Available A prototype detector is being developed which combines the functions of a Time Projection Chamber for charged particle tracking and a Cherenkov detector for particle identification. The TPC consists of a 10×10×10 cm3 drift volume where the charge is drifted to a 10×10 cm2 triple GEM detector. The charge is measured on a readout plane consisting of 2×10 mm2 chevron pads which provide a spatial resolution ∼ 100 μm per point in the chevron direction along with dE/dx information. The Cherenkov portion of the detector consists of a second 10×10 cm2 triple GEM with a photosensitive CsI photocathode on the top layer. This detector measures Cherenkov light produced in the drift gas of the TPC by high velocity particles which are above threshold. CF4 or CF4 mixtures will be used as the drift gas which are highly transparent to UV light and can provide excellent efficiency for detecting Cherenkov photons. The drift gas is also used as the operating gas for both GEM detectors. The prototype detector has been constructed and is currently being tested in the lab with sources and cosmic rays, and additional tests are planned in the future to study the detector in a test beam.

A Prototype Combination TPC Cherenkov Detector with GEM Readout for Tracking and Particle Identification and its Potential Use at an Electron Ion Collider

Science.gov (United States)

Woody, Craig; Azmoun, Babak; Majka, Richard; Phipps, Michael; Purschke, Martin; Smirnov, Nikolai

2018-02-01

A prototype detector is being developed which combines the functions of a Time Projection Chamber for charged particle tracking and a Cherenkov detector for particle identification. The TPC consists of a 10×10×10 cm3 drift volume where the charge is drifted to a 10×10 cm2 triple GEM detector. The charge is measured on a readout plane consisting of 2×10 mm2 chevron pads which provide a spatial resolution ˜ 100 μm per point in the chevron direction along with dE/dx information. The Cherenkov portion of the detector consists of a second 10×10 cm2 triple GEM with a photosensitive CsI photocathode on the top layer. This detector measures Cherenkov light produced in the drift gas of the TPC by high velocity particles which are above threshold. CF4 or CF4 mixtures will be used as the drift gas which are highly transparent to UV light and can provide excellent efficiency for detecting Cherenkov photons. The drift gas is also used as the operating gas for both GEM detectors. The prototype detector has been constructed and is currently being tested in the lab with sources and cosmic rays, and additional tests are planned in the future to study the detector in a test beam.

ArgonCube: a Modular Approach for Liquid Argon TPC Neutrino Detectors for Near Detector Environments

CERN Document Server

Auger, M; Sinclair, JR

2017-01-01

Liquid Argon Time Projection Chambers (LAr TPCs) are an ideal detector candidate for future neutrino oscillation physics experiments, underground neutrino observatories and proton decay searches. A large international project based on this technology is currently under consideration at the future LBNF/DUNE facility in the United States. That particular endeavor would be on the very large mass scale of 40~kt. Following diverse and long standing R\\&D work conducted over several years, with contributions from international collaborators, we propose a novel LAr TPC based on a fully-modular, innovative design, ArgonCube. ArgonCube will demonstrate that LAr TPCs are a viable detector technology for high-energy and high-multiplicity environments, such as the DUNE near detector. Necessary R\\&D work is proceeding along two main pathways; the first, aimed at the demonstration of modular detector design and the second, at the exploration of new signal readout methods. This two-pronged approach has provided a hig...

Precision meson spectroscopy. Diffractive production at COMPASS and development of a GEM-based TPC for PANDA

Energy Technology Data Exchange (ETDEWEB)

Weitzel, Quirin

2008-09-24

Meson spectroscopy is a unique way to access Quantum Chromo Dynamics (QCD) and learn about its properties. Due to the non-Abelian structure, QCD predicts new states of matter with gluonic degrees of freedom. In particular q anti qg hybrids, which can have spin-exotic quantum numbers forbidden for conventional q anti q mesons, are expected to exist. Such states were searched for in the past, mostly in the light-quark sector. However, the experimental situation is still ambiguous and needs to be clarified. Further insights will certainly also come from the heavy-quark spectroscopy. Several new charmonium-like resonances were for example discovered during the last years, which have to be studied in more detail by future experiments to reveal their nature. Diffractive dissociation reactions at COMPASS provide clean access to meson resonances with masses below 2.5 GeV/c{sup 2}. During a pilot run in 2004 using pion beams on lead targets, a competitive number of {pi}{sup -}{pi}{sup -}{pi}{sup +} final state events were recorded within a few days of data taking. A full partial wave analysis (PWA) of these data has been performed for this dissertation, concentrating on the kinematic domain of large momentum transfer (t' element of [0.1, 1.0] GeV{sup 2}/c{sup 2}). While well-known mesons are resolved with high quality, also a strong signal consistent with the much disputed hybrid candidate {pi}{sub 1}(1600) is observed in the spin-exotic J{sup PC} = 1{sup -+} partial wave. A Breit-Wigner parameterization yields a mass and width of 1.660{sup +0.010}{sub -0.074} and 0.269{sup +0.063}{sub -0.085} GeV/c{sup 2}, respectively. In addition, a first PWA of events with small momentum transfer (t' element of [10{sup -3},10{sup -2}] GeV{sup 2}/c{sup 2}) has been carried out, yielding several high-mass radial-excitation states. In the future, the PANDA experiment at the FAIR facility will perform highprecision spectroscopy in the charm-sector employing anti pp annihilations

Bilateral ocular abnormalities in a wild stranded harp seal (Phoca groenlandica) suggestive of anterior segment dysgenesis and persistent hyperplastic primary vitreous.

Science.gov (United States)

Erlacher-Reid, Claire; Colitz, Carmen M H; Abrams, Ken; Smith, Ainsley; Tuttle, Allison D

2011-06-01

A male yearling harp seal (Phoca groenlandica) stranded and was brought to Mystic Aquarium & Institute for Exploration's Seal Rescue and Rehabilitation Center. The seal presented with a bilateral pendular vertical nystagmus, negative menace response, and a positive palpebral response. Ophthalmological examination by slit lamp biomicroscopy revealed perilimbal corneal edema, excessive iridal surface structures, pupils that appeared to be shaped improperly (dyscoria), and suspected cataracts. Attempts to dilate the pupils with both dark-lighted conditions and repeated dosages of 10% phenylephrine and 1% atropine ophthalmic solution in each eye (OU) were unsuccessful. Ocular ultrasonography findings suggested bilateral cataracts with flattened anterior-posterior (A-P) diameter and possible persistent hyperplastic primary vitreous. It is possible that these structural congenital abnormalities could produce further ocular complications for this seal including uveitis, secondary glaucoma, retinal detachment, and/or vitreal hemorrhage in the future. This case demonstrates the importance of a thorough ophthalmological examination in stranded wild animals, especially if their symptoms appear neurological.

Large-angle production of charged pions by 3 GeV/c - 12 GeV/c protons on carbon, copper and tin targets

CERN Document Server

Catanesi, M.G.; Ellis, Malcolm; Robbins, S.; Soler, F.J.P.; Gossling, C.; Bunyatov, S.; Krasnoperov, A.; Popov, B.; Serdiouk, V.; Tereschenko, V.; Di Capua, E.; Vidal-Sitjes, G.; Artamonov, A.; Arce, P.; Giani, S.; Gilardoni, S.; Gorbunov, P.; Grant, A.; Grossheim, A.; Gruber, P.; Ivanchenko, V.; Kayis-Topaksu, A.; Panman, J.; Papadopoulos, I.; Pasternak, J.; Tcherniaev, E.; Tsukerman, I.; Veenhof, R.; Wiebusch, C.; Zucchelli, P.; Blondel, A.; Borghi, S.; Campanelli, M.; Morone, M.C.; Prior, G.; Schroeter, R.; Engel, R.; Meurer, C.; Kato, I.; Gastaldi, U.; Mills, G.B.; Graulich, J.S.; Gregoire, G.; Bonesini, M.; Ferri, F.; Paganoni, M.; Paleari, F.; Kirsanov, M.; Bagulya, A.; Grichine, V.; Polukhina, M.; Palladino, V.; Coney, L.; Schmitz, D.; Barr, G.; De Santo, A.; Pattison, C.; Zuber, K.; Bobisut, F.; Gibin, D.; Guglielmi, A.; Mezzetto, M.; Dumarchez, J.; Vannucci, F.; Dore, U.; Orestano, D.; Pastore, F.; Tonazzo, A.; Tortora, L.; Booth, C.; Buttar, C.; Hodgson, P.; howlett, L.; Bogomilov, M.; Chizhov, M.; Kolev, D.; Tsenov, R.; Piperov, Stefan; Temnikov, P.; Apollonio, M.; Chimenti, P.; Giannini, G.; Santin, G.; Burguet-Castell, J.; Cervera-Villanueva, A.; Gomez-Cadenas, J.J.; Martin-Albo, J.; Novella, P.; Sorel, M.; Tornero, A.

2008-01-01

A measurement of the double-differential $\\pi^{\\pm}$ production cross-section in proton--carbon, proton--copper and proton--tin collisions in the range of pion momentum $100 \\MeVc \\leq p < 800 \\MeVc$ and angle $0.35 \\rad \\le \\theta <2.15 \\rad$ is presented. The data were taken with the HARP detector in the T9 beam line of the CERN PS. The pions were produced by proton beams in a momentum range from 3 \\GeVc to 12 \\GeVc hitting a target with a thickness of 5% of a nuclear interaction length. The tracking and identification of the produced particles was done using a small-radius cylindrical time projection chamber (TPC) placed in a solenoidal magnet. An elaborate system of detectors in the beam line ensured the identification of the incident particles. Results are shown for the double-differential cross-sections at four incident proton beam momenta (3 \\GeVc, 5 \\GeVc, 8 \\GeVc and 12 \\GeVc).

Arthroscopic Surgical Procedures Versus Sham Surgery for Patients With Femoroacetabular Impingement and/or Labral Tears: Study Protocol for a Randomized Controlled Trial (HIPARTI) and a Prospective Cohort Study (HARP).

Science.gov (United States)

Risberg, May Arna; Ageberg, Eva; Nilstad, Agnethe; Lund, Bent; Nordsletten, Lars; Løken, Sverre; Ludvigsen, Tom; Kierkegaard, Signe; Carsen, Sasha; Kostogiannis, Ioannis; Crossley, Kay M; Glyn-Jones, Sion; Kemp, Joanne L

2018-04-01

Study Design Study protocol for a randomized controlled trial and a prospective cohort. Background The number of arthroscopic surgical procedures for patients with femoroacetabular impingement syndrome (FAIS) has significantly increased worldwide, but high-quality evidence of the effect of such interventions is lacking. Objectives The primary objective will be to determine the efficacy of hip arthroscopic procedures compared to sham surgery on patient-reported outcomes for patients with FAIS (HIP ARThroscopy International [HIPARTI] Study). The secondary objective will be to evaluate prognostic factors for long-term outcome after arthroscopic surgical interventions in patients with FAIS (Hip ARthroscopy Prospective [HARP] Study). Methods The HIPARTI Study will include 140 patients and the HARP Study will include 100 patients. The international Hip Outcome Tool-33 will be the primary outcome measure at 1 year. Secondary outcome measures will be the Hip disability and Osteoarthritis Outcome Score, Arthritis Self-Efficacy Scale, fear of movement (Tampa Scale of Kinesiophobia), Patient-Specific Functional Scale, global rating of change score, and expectations. Other outcomes will include active hip range of motion, hip muscle strength tests, functional performance tests, as well as radiological assessments using radiographs and magnetic resonance imaging. Conclusion To determine the true effect of surgery, beyond that of placebo, double-blinded placebo-controlled trials including sham surgery are needed. The HIPARTI Study will direct future evidence-based treatment of FAIS. Predictors for long-term development and progression of degenerative changes in the hip are also needed for this young patient group with FAIS; hence, responders and nonresponders to treatment could be determined. J Orthop Sports Phys Ther 2018;48(4):325-335. doi:10.2519/jospt.2018.7931.

Developing Light Collection Enhancements and Wire Tensioning Methods for LArTPC Neutrino Detectors

Energy Technology Data Exchange (ETDEWEB)

Spagliardi, Fabio [Univ. of Manchester (United Kingdom)

2017-01-01

Liquid argon Time Projection Chambers (LArTPCs) are becoming widely used as neutrino detectors because of their image-like event reconstruction which enables precision neutrino measurements. They primarily use ionisation charge to reconstruct neutrino events. It has been shown, however, that the scintillation light emitted by liquid argon could be exploited to improve their performance. As the neutrino measurements planned in the near future require large-scale experiments, their construction presents challenges in terms of both charge and light collection. In this dissertation we present solutions developed to improve the performance in both aspects of these detectors. We present a new wire tensioning measurement method that allows a remote measurement of the tension of the large number wires that constitute the TPC anode. We also discuss the development and installation of WLS-compound covered foils for the SBND neutrino detector at Fermilab, which is a technique proposed t o augment light collection in LArTPCs. This included preparing a SBND-like mesh cathode and testing it in the Run III of LArIAT, a test beam detector also located at Fermilab. Finally, we present a study aimed at understanding late scintillation light emitted by recombining positive argon ions using LArIAT data, which could affect large scale surface detectors.

Charge Sensitive Amplifier (CSA) in cold gas of Liquid Argon (LAr) Time Projection Chamber (TPC)

International Nuclear Information System (INIS)

Bechetoille, E; Mathez, H; Zoccarato, Y

2011-01-01

This paper presents our work on a 8-channel low noise Front-End electronic coupled to a Liquid Argon (LAr) TPC (Time Projection Chamber). Each channel consists of a Charge Sensitive Amplifier (CSA), a band pass filter and a 50 Ohms buffer as line driver. A serial link based on a 'i2c-like' protocol, provides multiple configuration features to the circuit by accessing slow control registers. In this paper, we describe the CSA, the shaper and the slow control part. The feedback network of the CSA is made of a capacitance and a resistor. Their values are respectively 250 fF and 4 MΩ. An input referred noise of, at most, 1500 e- rms must be achieved at -100 deg. C with an input detector capacitance of 250 pF to ensure a correct measurement of the minimal signal of 18000e- (2.88 fC). The power consumption in this cryogenic setup must be less than 40 mW from a 3.3 V power supply.

Radiation tolerance studies using fault injection on the Readout Control FPGA design of the ALICE TPC detector

Science.gov (United States)

Alme, J.; Fehlker, D.; Lippmann, C.; Mager, M.; Rehman, A. U.; Røed, K.; Röhrich, D.; Ullaland, K.

2013-01-01

Single Event Upsets (SEUs) are a major concern for the TPC Readout Control Unit (RCU) of the ALICE experiment. A SEU is defined as a radiation related bit-flip in a memory cell, and a SEU in the onboard SRAM based FPGA of the RCU may lead to corrupted data or, even worse, a system malfunction. The latter situation will affect the operation of the ALICE detector since it causes a premature end of data taking. Active partial reconfiguration is utilized in a dedicated reconfiguration solution on the RCU, and this makes it possible to implement fault injection. Fault injection means inserting bit flips in the configuration memory of the FPGA in a controlled laboratory environment. This paper presents the results of the fault injection study and shows how this result can be combined with SEU measurements to estimate the functional failure rate as a function of luminosity.

Observation of short range three-particle correlations in e+e- annihilations at LEP energies

CERN Document Server

Abreu, P; Adye, T; Agasi, E; Ajinenko, I; Aleksan, Roy; Alekseev, G D; Allport, P P; Almehed, S; Alvsvaag, S J; Amaldi, Ugo; Amato, S; Andreazza, A; Andrieux, M L; Antilogus, P; Apel, W D; Arnoud, Y; Augustin, J E; Augustinus, A; Baillon, Paul; Bambade, P; Barate, R; Barbiellini, Guido; Bardin, Dimitri Yuri; Barker, G J; Baroncelli, A; Barrio, J A; Bartl, Walter; Barão, F; Bates, M J; Battaglia, Marco; Baubillier, M; Baudot, J; Becks, K H; Begalli, M; Beillière, P; Belokopytov, Yu A; Belous, K S; Benvenuti, Alberto C; Berggren, M; Bertrand, D; Bianchi, F; Bigi, M; Bilenky, S M; Billoir, P; Bloch, D; Blume, M; Blyth, S; Bocci, V; Bolognese, T; Bonesini, M; Bonivento, W; Booth, P S L; Borisov, G; Bosio, C; Bosworth, S; Botner, O; Bouquet, B; Bourdarios, C; Bowcock, T J V; Bozzo, M; Branchini, P; Brand, K D; Brenner, R A; Bricman, C; Brillault, L; Brown, R C A; Brunet, J M; Brückman, P; Bugge, L; Buran, T; Buys, A; Bärring, O; Caccia, M; Calvi, M; Camacho-Rozas, A J; Camporesi, T; Canale, V; Canepa, M; Cankocak, K; Cao, F; Carena, F; Carrilho, P; Carroll, L; Caso, Carlo; Castillo-Gimenez, M V; Cattai, A; Cavallo, F R; Cerrito, L; Chabaud, V; Charpentier, P; Chaussard, L; Chauveau, J; Checchia, P; Chelkov, G A; Chierici, R; Chochula, P; Chorowicz, V; Cindro, V; Collins, P; Contreras, J L; Contri, R; Cortina, E; Cosme, G; Cossutti, F; Crawley, H B; Crennell, D J; Crosetti, G; Cuevas-Maestro, J; Czellar, S; D'Almagne, B; Da Silva, W; Dahl-Jensen, Erik; Dahm, J; Dam, M; Damgaard, G; Daum, A; Dauncey, P D; Davenport, Martyn; De Angelis, A; De Boeck, H; De Brabandere, S; De Clercq, C; De Lotto, B; De Min, A; De Paula, L S; De Saint-Jean, C; Defoix, C; Della Ricca, G; Delpierre, P A; Demaria, N; Di Ciaccio, Lucia; Dijkstra, H; Djama, F; Dolbeau, J; Doroba, K; Dracos, M; Drees, J; Drees, K A; Dris, M; Dufour, Y; Dupont, F; Dönszelmann, M; Edsall, D M; Ehret, R; Eigen, G; Ekelöf, T J C; Ekspong, Gösta; Elsing, M; Engel, J P; Ershaidat, N; Erzen, B; Espirito-Santo, M C; Falk, E; Fassouliotis, D; Feindt, Michael; Fenyuk, A; Ferrer, A; Filippas-Tassos, A; Firestone, A; Fischer, P A; Fokitis, E; Fontanelli, F; Formenti, F; Franek, B J; Frenkiel, P; Fries, D E C; Frodesen, A G; Frühwirth, R; Fulda-Quenzer, F; Fuster, J A; Föth, H; Fürstenau, H; Galloni, A; Gamba, D; Gandelman, M; García, C; García, J; Gaspar, C; Gasparini, U; Gavillet, P; Gazis, E N; Gelé, D; Gerber, J P; Gibbs, M; Gillespie, D; Gokieli, R; Golob, B; Gopal, Gian P; Gorn, L; Gracco, Valerio; Graziani, E; Grosdidier, G; Gunnarsson, P; Guy, J; Guz, Yu; Górski, M; Günther, M; Haedinger, U; Hahn, F; Hahn, M; Hahn, S; Hajduk, Z; Hallgren, A; Hamacher, K; Hao, W; Harris, F J; Hedberg, V; Henriques, R P; Hernández, J J; Herquet, P; Herr, H; Hessing, T L; Higón, E; Hilke, Hans Jürgen; Hill, T S; Holmgren, S O; Holt, P J; Holthuizen, D J; Houlden, M A; Huet, K; Hultqvist, K; Ioannou, P; Jackson, J N; Jacobsson, R; Jalocha, P; Janik, R; Jarlskog, G; Jarry, P; Jean-Marie, B; Johansson, E K; Joram, Christian; Juillot, P; Jönsson, L B; Jönsson, P E; Kaiser, M; Kalmus, George Ernest; Kapusta, F; Karlsson, M; Karvelas, E; Katargin, A; Katsanevas, S; Katsoufis, E C; Keränen, R; Khomenko, B A; Khovanskii, N N; King, B J; Kjaer, N J; Klein, H; Klovning, A; Kluit, P M; Kokkinias, P; Koratzinos, M; Kostyukhin, V; Kourkoumelis, C; Kramer, P H; Krammer, Manfred; Kreuter, C; Kronkvist, I J; Krumshtein, Z; Krupinski, W; Królikowski, J; Kubinec, P; Kucewicz, W; Kurvinen, K L; Kuznetsov, O; Köhne, J H; Köne, B; La Vaissière, C de; Lacasta, C; Laktineh, I; Lamblot, S; Lamsa, J; Lanceri, L; Lane, D W; Langefeld, P; Lapin, V; Last, I; Laugier, J P; Lauhakangas, R; Leder, Gerhard; Ledroit, F; Lefébure, V; Legan, C K; Leitner, R; Lemoigne, Y; Lemonne, J; Lenzen, Georg; Lepeltier, V; Lesiak, T; Liko, D; Lindner, R; Lipniacka, A; Lippi, I; Lokajícek, M; Loken, J G; Loukas, D; Lutz, P; Lyons, L; López, J M; López-Aguera, M A; López-Fernandez, A; Lörstad, B; MacNaughton, J N; Maehlum, G; Maio, A; Malychev, V; Mandl, F; Marco, J; Margoni, M; Marin, J C; Mariotti, C; Markou, A; Maron, T; Martí i García, S; Martínez-Rivero, C; Martínez-Vidal, F; Maréchal, B; Matorras, F; Matteuzzi, C; Matthiae, Giorgio; Mazzucato, M; McCubbin, M L; McKay, R; McNulty, R; Medbo, J; Meroni, C; Meyer, W T; Michelotto, M; Migliore, E; Mirabito, L; Mitaroff, Winfried A; Mjörnmark, U; Moa, T; Monge, M R; Morettini, P; Mundim, L M; Murray, W J; Muryn, B; Myagkov, A; Myatt, Gerald; Mönig, K; Møller, R; Müller, H; Naraghi, F; Navarria, Francesco Luigi; Navas, S; Negri, P; Neumann, W; Neumeister, N; Nicolaidou, R; Nielsen, B S; Nieuwenhuizen, M; Nikolaenko, V; Niss, P; Nomerotski, A; Normand, Ainsley; Némécek, S; Oberschulte-Beckmann, W; Obraztsov, V F; Olshevskii, A G; Onofre, A; Orava, Risto; Ouraou, A; Paganini, P; Paganoni, M; Pagès, P; Palka, H; Papadopoulou, T D; Pape, L; Parkes, C; Parodi, F; Passeri, A; Pegoraro, M; Peralta, L; Pernegger, H; Pernicka, Manfred; Perrotta, A; Petridou, C; Petrolini, A; Phillips, H T; Piana, G; Pierre, F; Pimenta, M; Plaszczynski, S; Podobrin, O; Pol, M E; Polok, G; Poropat, P; Pozdnyakov, V; Prest, M; Privitera, P; Pukhaeva, N; Pullia, Antonio; Radojicic, D; Ragazzi, S; Rahmani, H; Rames, J; Ratoff, P N; Read, A L; Reale, M; Rebecchi, P; Redaelli, N G; Regler, Meinhard; Reid, D; Renton, P B; Resvanis, L K; Richard, F; Richardson, J; Rinaudo, G; Ripp, I; Romero, A; Roncagliolo, I; Ronchese, P; Roos, L; Rosenberg, E I; Rosso, E; Roudeau, Patrick; Rovelli, T; Ruhlmann-Kleider, V; Ruiz, A; Rídky, J; Rückstuhl, W; Saarikko, H; Sacquin, Yu; Sadovskii, A; Sajot, G; Salt, J; Sannino, M; Schneider, H; Schyns, M A E; Sciolla, G; Scuri, F; Sedykh, Yu; Segar, A M; Seitz, A; Sekulin, R L; Shellard, R C; Siccama, I; Siegrist, P; Simonetti, S; Simonetto, F; Sissakian, A N; Sitár, B; Skaali, T B; Smadja, G; Smirnov, N; Smirnova, O G; Smith, G R; Sokolov, A; Sosnowski, R; Souza-Santos, D; Spassoff, Tz; Spiriti, E; Squarcia, S; Stanescu, C; Stapnes, Steinar; Stavitski, I; Stepaniak, K; Stichelbaut, F; Stocchi, A; Strauss, J; Strub, R; Stugu, B; Stäck, H; Szczekowski, M; Szeptycka, M; Sánchez, J; Tabarelli de Fatis, T; Tavernet, J P; Tilquin, A; Timmermans, J; Tkatchev, L G; Todorov, T; Toet, D Z; Tomaradze, A G; Tomé, B; Tortora, L; Tranströmer, G; Treille, D; Trischuk, W; Tristram, G; Trombini, A; Troncon, C; Tsirou, A L; Turluer, M L; Tyapkin, I A; Tyndel, M; Tzamarias, S; Ullaland, O; Valenti, G; Vallazza, E; Van Eldik, J; Van der Velde, C; Vassilopoulos, N; Vegni, G; Ventura, L; Venus, W A; Verbeure, F; Verlato, M; Vertogradov, L S; Vilanova, D; Vincent, P; Vitale, L; Vlasov, E; Vodopyanov, A S; Vrba, V; Wahlen, H; Walck, C; Wehr, A; Weierstall, M; Weilhammer, Peter; Wetherell, Alan M; Wicke, D; Wickens, J H; Wielers, M; Wilkinson, G R; Williams, W S C; Winter, M; Witek, M; Woschnagg, K; Yip, K; Yushchenko, O P; Zach, F; Zacharatou-Jarlskog, C; Zaitsev, A; Zalewska-Bak, A; Zalewski, Piotr; Zavrtanik, D; Zevgolatakos, E; Zimin, N I; Zito, M; Zontar, D; Zuberi, R; Zucchelli, G C; Zumerle, G; de Boer, Wim; van Apeldoorn, G W; van Dam, P; Åsman, B; Österberg, K; Überschär, B; Überschär, S

1995-01-01

\\def\\tpc{three-particle correlation} \\def\\twopc{two-particle correlation} Measurements are presented of short range three-particle correlations in e^+ e^- annihilations at LEP using data collected by the DELPHI detector. %The jet structure is studied using three-particle correlation functions. At small values of the four-momentum difference, strong three-particle correlations are observed for like-sign (+++ and ---) and for unlike-sign (++- and +--) pion combinations which are not a consequence of two-particle correlations. A possible explanation of the observed effects in like-sign combinations is the existence of higher order Bose-Einstein interference, which significantly changes the particle distributions in jets.

Quantitative Phylogenomics of Within-Species Mitogenome Variation: Monte Carlo and Non-Parametric Analysis of Phylogeographic Structure among Discrete Transatlantic Breeding Areas of Harp Seals (Pagophilus groenlandicus.

Directory of Open Access Journals (Sweden)

Steven M Carr

Full Text Available Phylogenomic analysis of highly-resolved intraspecific phylogenies obtained from complete mitochondrial DNA genomes has had great success in clarifying relationships within and among human populations, but has found limited application in other wild species. Analytical challenges include assessment of random versus non-random phylogeographic distributions, and quantification of differences in tree topologies among populations. Harp Seals (Pagophilus groenlandicus Erxleben, 1777 have a biogeographic distribution based on four discrete trans-Atlantic breeding and whelping populations located on "fast ice" attached to land in the White Sea, Greenland Sea, the Labrador ice Front, and Southern Gulf of St Lawrence. This East to West distribution provides a set of a priori phylogeographic hypotheses. Outstanding biogeographic questions include the degree of genetic distinctiveness among these populations, in particular between the Greenland Sea and White Sea grounds. We obtained complete coding-region DNA sequences (15,825 bp for 53 seals. Each seal has a unique mtDNA genome sequence, which differ by 6 ~ 107 substitutions. Six major clades / groups are detectable by parsimony, neighbor-joining, and Bayesian methods, all of which are found in breeding populations on either side of the Atlantic. The species coalescent is at 180 KYA; the most recent clade, which accounts for 66% of the diversity, reflects an expansion during the mid-Wisconsinan glaciation 40~60 KYA. FST is significant only between the White Sea and Greenland Sea or Ice Front populations. Hierarchal AMOVA of 2-, 3-, or 4-island models identifies small but significant ΦSC among populations within groups, but not among groups. A novel Monte-Carlo simulation indicates that the observed distribution of individuals within breeding populations over the phylogenetic tree requires significantly fewer dispersal events than random expectation, consistent with island or a priori East to West 2- or 3

The study of hadronic matter at the highest density; the search for the deconfined quark-gluon phase using 2 TeV anti p-p collisions; and the exclusive study of nuclear fragmentation using the Lawrence Berkeley Laboratory EOS-TPC

International Nuclear Information System (INIS)

Scharenberg, R.P.; Hirsch, A.S.

1990-01-01

This report discusses the: Fermilab experiment 735, a search for the quark-gluon plasma; an exclusive study of nuclear fragmentation using the EOS-TPC; and a study of the central rapidity region at the relativistic heavy ion collider

Levels of non-essential elements in muscle from harp seal (Phagophilus groenlandicus) and hooded seal (Cystophora cristata) caught in the Greenland Sea area

International Nuclear Information System (INIS)

Brunborg, Linn Anne; Graff, Ingvild Eide; Froyland, Livar; Julshamn, Kare

2006-01-01

The non-essential elements, arsenic, cadmium, mercury and lead, inevitably accumulate in marine top predators such as seals. The concentration of these elements and the essential element selenium, due to its proposed protective properties against mercury toxicity in marine mammals, were measured in muscle, liver and kidney from reproductive active females of harp seal (Phagophilus groenlandicus) and hooded seal (Cystophora cristata) caught in the drift ice between Iceland and East Greenland. Arsenic levels were below 1 μg/g w.w. in all analysed samples, and were therefore low compared to other seafood products. The concentrations of arsenic found in the present study were comparable to the results reported in a similar study from 1985. Mean concentrations of total mercury in muscle from the present study were higher than levels in other seafood products. The levels of total mercury from the present study showed a tendency of lower levels in all tissue samples compared to the study from 1985. Methyl mercury displayed a trend of a lower ratio of methyl mercury to total mercury as the concentration of total mercury increased, indicating a demethylation of methyl mercury at high total mercury concentrations (e.g. mercury in liver of hooded seal). The concentration ratio of methyl mercury to total mercury in muscle samples was more than 75%, with total mercury concentration less than 0.5 μg/g w.w., whereas the ratio for liver was as low as 0.2% with a total mercury concentration of 128 μg/g w.w. The molar concentration ratios of selenium to mercury showed that selenium was present in a molar surplus to mercury in all tissues with low mercury concentration. However, there seemed to be a general mobilisation of selenium in liver and kidney tissues of harp seal and hooded seal, whereas an extraordinary mobilisation seemed to take place at hepatic mercury concentrations exceeding 50 μg/g w.w. The mean concentrations of lead in muscles in the present study were higher

Long-term radial-velocity variations of the Sun as a star: The HARPS view

Science.gov (United States)

Lanza, A. F.; Molaro, P.; Monaco, L.; Haywood, R. D.

2016-03-01

Context. Stellar radial velocities play a fundamental role in the discovery of extrasolar planets and the measurement of their physical parameters as well as in the study of stellar physical properties. Aims: We investigate the impact of the solar activity on the radial velocity of the Sun using the HARPS spectrograph to obtain measurements that can be directly compared with those acquired in the extrasolar planet search programmes. Methods: We used the Moon, the Galilean satellites, and several asteroids as reflectors to measure the radial velocity of the Sun as a star and correlated this velocity with disc-integrated chromospheric and magnetic indexes of solar activity that are similar to stellar activity indexes. We discuss in detail the systematic effects that affect our measurements and the methods to account for them. Results: We find that the radial velocity of the Sun as a star is positively correlated with the level of its chromospheric activity at ~95 percent significance level. The amplitude of the long-term variation measured in the 2006-2014 period is 4.98 ± 1.44 m/s, which is in good agreement with model predictions. The standard deviation of the residuals obtained by subtracting a linear best fit is 2.82 m/s and is due to the rotation of the reflecting bodies and the intrinsic variability of the Sun on timescales shorter than the activity cycle. A correlation with a lower significance is detected between the radial velocity and the mean absolute value of the line-of-sight photospheric magnetic field flux density. Conclusions: Our results confirm similar correlations found in other late-type main-sequence stars and provide support to the predictions of radial velocity variations induced by stellar activity based on current models.

Effects of different extracts of curcumin on TPC1 papillary thyroid cancer cell line.

Science.gov (United States)

Perna, Angelica; De Luca, Antonio; Adelfi, Laura; Pasquale, Tammaro; Varriale, Bruno; Esposito, Teresa

2018-02-15

The thyroid gland is one of the largest endocrine glands in the body. The vast majority of TCs (> 90%) originate from follicular cells and are defined as differentiated thyroid cancers (DTC) and the two histological subtypes are the papillary TC with its variants and the follicular TC. Curcumin possesses a wide variety of biological functions, and thanks to its properties, it has gained considerable attention due to its profound medicinal values (Prasad, Gupta, Tyagi, and Aggarwal, Biotechnol Adv 32:1053-1064, 2014). We have undertaken the present work in order to define the possible role of curcumin in modulating the genetic expression of cell markers and to understand the effectiveness of this nutraceutical in modulating the regression of cancer phenotype. As a template we used the TPC-1 cells treated with the different extracts of turmeric, and examined the levels of expression of different markers (proliferative, inflammatory, antioxidant, apoptotic). Treatment with the three different curcumin extracts displays anti-inflammatory, antioxidant properties and it is able to influence cell cycle with slightly different effects upon the extracts. Furthermore curcumin is able to influence cell metabolic activity vitality. In conclusion curcumin has the potential to be developed as a safe therapeutic but further studies are needed to verify its antitumor ability in vivo.

First measurement of the polarisation asymmetry of a gamma-ray beam between 1.7 to 74 MeV with the HARPO TPC

Science.gov (United States)

Gros, P.; Amano, S.; Attié, D.; Bernard, D.; Bruel, P.; Calvet, D.; Colas, P.; Daté, S.; Delbart, A.; Frotin, M.; Geerebaert, Y.; Giebels, B.; Götz, D.; Hashimoto, S.; Horan, D.; Kotaka, T.; Louzir, Marc; Minamiyama, Y.; Miyamoto, S.; Ohkuma, H.; Poilleux, Patrick; Semeniouk, I.; Sizun, P.; Takemoto, A.; Yamaguchi, M.; Wang, S.

2016-07-01

Current γ-ray telescopes suffer from a gap in sensitivity in the energy range between 100 keV and 100 MeV, and no polarisation measurement has ever been done on cosmic sources above 1 MeV. Past and present e+e- pair telescopes are limited at lower energies by the multiple scattering of electrons in passive tungsten converter plates. This results in low angular resolution, and, consequently, a drop in sensitivity to point sources below 1 GeV. The polarisation information, which is carried by the azimuthal angle of the conversion plane, is lost for the same reasons. HARPO is an R&D program to characterise the operation of a gaseous detector (a Time Projection Chamber or TPC) as a high angular-resolution and sensitivity telescope and polarimeter for γ-rays from cosmic sources. It represents a first step towards a future space instrument in the MeV-GeV range. We built and characterised a 30cm cubic demonstrator [SPIE 91441M], and put it in a polarised γ-ray beam at the NewSUBARU accelerator in Japan. Data were taken at photon energies from 1.74MeV to 74MeV and with different polarisation configurations. We describe the experimental setup in beam. We then describe the software we developed to reconstruct the photon conversion events, with special focus on low energies. We also describe the thorough simulation of the detector used to compare results. Finally we will present the performance of the detector as extracted from this analysis and preliminary measurements of the polarisation asymmetry. This beam-test qualification of a gas TPC prototype in a γ-ray beam could open the way to high-performance -ray astronomy and polarimetry in the MeV-GeV energy range in the near future.

VizieR Online Data Catalog: Radial velocities for the HD 3167 system (Christiansen+, 2017)

Science.gov (United States)

Christiansen, J. L.; Vanderburg, A.; Burt, J.; Fulton, B. J.; Batygin, K.; Benneke, B.; Brewer, J. M.; Charbonneau, D.; Ciardi, D. R.; Cameron, A. C.; Coughlin, J. L.; Crossfield, I. J. M.; Dressing, C.; Greene, T. P.; Howard, A. W.; Latham, D. W.; Molinari, E.; Mortier, A.; Mullally, F.; Pepe, F.; Rice, K.; Sinukoff, E.; Sozzetti, A.; Thompson, S. E.; Udry, S.; Vogt, S. S.; Barman, T. S.; Batalha, N. E.; Bouchy, F.; Buchhave, L. A.; Butler, R. P.; Cosentino, R.; Dupuy, T. J.; Ehrenreich, D.; Fiorenzano, A.; Hansen, B. M. S.; Henning, T.; Hirsch, L.; Holden, B. P.; Isaacson, H. T.; Johnson, J. A.; Knutson, H. A.; Kosiarek, M.; Lopez-Morales, M.; Lovis, C.; Malavolta, L.; Mayor, M.; Micela, G.; Motalebi, F.; Petigura, E.; Phillips, D. F.; Piotto, G.; Rogers, L. A.; Sasselov, D.; Schlieder, J. E.; Segransan, D.; Watson, C. A.; Weiss, L. M.

2018-06-01

The final data set includes observations obtained with Keck/HIRES, Automated Planet Finder (APF)/Levy, and HARPS-N. Our observational setup for both Keck/HIRES and the APF/Levy was essentially identical to those described in Fulton et al. (2016, J/ApJ/830/46) and Burt et al. (2014ApJ...789..114B). We collected a total of 60 RV measurements using Keck/HIRES (Vogt et al. 1994SPIE.2198..362V), and 116 measurements using the Levy Spectrograph on the APF (Radovan et al. 2014SPIE.9145E..2BR; Vogt et al. 2014PASP..126..359V) at Lick Observatory between 2016 July 7 and 2016 December 2. We also observed HD 3167 with the HARPS-N spectrograph (Cosentino et al. 2012SPIE.8446E..1VC) located at the 3.58 m Telescopio Nazionale Galileo on the island of La Palma, Spain. HARPS-N is a stabilized spectrograph designed for precise RV measurements. We observed HD 3167 76 times between 2016 July 7 (independently beginning the same night as the HIRES/APF campaign) and 2016 December 7, obtaining high-resolution optical spectra with a spectral resolving power of R=115000. (1 data file).

ArgonCube: a novel, fully-modular approach for the realization of large-mass liquid argon TPC neutrino detectors

CERN Document Server

Amsler, C; Asaadi, J; Auger, M; Barbato, F; Bay, F; Bishai, M; Bleiner, D; Borgschulte, A; Bremer, J; Cavus, E; Chen, H; De Geronimo, G; Ereditato, A; Fleming, B; Goldi, D; Hanni, R; Kose, U; Kreslo, I; La Mattina, F; Lanni, F; Lissauer, D; Luthi, M; Lutz, P; Marchionni, A; Mladenov, D; Nessi, M; Noto, F; Palamara, O; Raaf, J L; Radeka, V; Rudolph Von Rohr, Ch; Smargianaki, D; Soderberg, M; Strauss, Th; Weber, M; Yu, B; Zeller, G P; Zeyrek, M; CERN. Geneva. SPS and PS Experiments Committee; SPSC

2015-01-01

The Liquid Argon Time Projection Chamber is a prime candidate detector for future neutrino oscillation physics experiments, underground neutrino observatories and proton decay searches. A large international project based on this technology is currently being considered at the future LBNF facility in the United States on the very large mass scale of 40 kton. In this document, following the long standing R&D work conducted over the last years in several laboratories in Europe and in the United States, we intend to propose a novel Liquid Argon TPC approach based on a fully-modular, innovative design, the ArgonCube. The related R&D work will proceed along two main directions; one aimed at on the assessment of the proposed modular detector design, the other on the exploitation of new signal readout methods. Such a strategy will provide high performance while being cost-effective and robust at the same time. According to our plans, we will firstly realize a detector prototype hosted in a cryostat that is a...

A GEM-TPC in twin configuration for the Super-FRS tracking of heavy ions at FAIR

Science.gov (United States)

García, F.; Grahn, T.; Hoffmann, J.; Jokinen, A.; Kaya, C.; Kunkel, J.; Rinta-Antila, S.; Risch, H.; Rusanov, I.; Schmidt, C. J.; Simon, H.; Simons, C.; Turpeinen, R.; Voss, B.; Äystö, J.; Winkler, M.

2018-03-01

The GEM-TPC described herein will be part of the standard beam-diagnostics equipment of the Super-FRS. This chamber will provide tracking information for particle identification at rates up to 1 MHz on an event-by-event basis. The key requirements of operation for these chambers are: close to 100% tracking efficiency under conditions of high counting rate, spatial resolution below 1 mm and a superb large dynamic range covering projectiles from Z = 1 up to Z = 92. The current prototype consists of two GEM-TPCs inside a single vessel, which are operating independently and have electrical drift fields in opposite directions. The twin configuration is done by flipping one of the GEM-TPCs on the middle plane with respect to the second one. In order to put this development in context, the evolution of previous prototypes will be described and its performances discussed. Finally, this chamber was tested at the University of Jyväskylä accelerator with proton projectiles and at GSI with Uranium, Xenon, fragments and Carbon beams. The results obtained have shown a position resolution between 120 to 300 μm at moderate counting rate under conditions of full tracking efficiency.

Measurement of electrons from heavy-flavour hadron decays in p-Pb collisions at $\\sqrt{s_{NN}} = 5.02$ TeV using TPC and EMCal detectors with ALICE at LHC

CERN Document Server

Jahnke, Cristiane

Heavy-ion collisions are a powerful tool to study hot and dense QCD matter, the so-called Quark Gluon Plasma (QGP). Since heavy quarks (charm and beauty) are dominantly produced in the early stages of the collision, they experience the complete evolution of the system. Measurements of electrons from heavy-flavour hadron decay is one possible way to study the interaction of these particles with the QGP. With ALICE at LHC, electrons can be identified with high efficiency and purity. A strong suppression of heavy-flavour decay electrons has been observed at high $p_{m T}$ in Pb-Pb collisions at 2.76 TeV. Measurements in p-Pb collisions are crucial to understand cold nuclear matter effects on heavy-flavour production in heavy-ion collisions. The spectrum of electrons from the decays of hadrons containing charm and beauty was measured in p-Pb collisions at $\\sqrt = 5.02$ TeV. The heavy flavour decay electrons were measured by using the Time Projection Chamber (TPC) and the Electromagnetic Calorimeter (EMCal) detec...

Observation of antioxidant activity of leaves, callus and suspension ...

African Journals Online (AJOL)

GREGORY

2011-12-16

Dec 16, 2011 ... Antioxidant activity and phenolic compound was found in Justicia gendarussa via total phenolic content (TPC) and α,α-diphenyl-β-pycrilhydrazil hydrate (DPPH) radical scavenging assays. The assays were applied on aqueous and methanolic extracts of leaves, callus culture and cell suspension culture.

A comprehensive search for “anomalies” from neutrino and anti-neutrino oscillations at large mass differences (Δm^2 ~ 1eV^2) with two LAr–TPC imaging detectors at different distances from the CERN-PS.

CERN Document Server

Rubbia, C; Bagliani, D; Baibussinov, B; Bilokon, H; Boffelli, F; Bonesini, M; Calligarich, E; Canci, N; Centro, S; Cesana, A; Cieslik, K; Cline, D B; Cocco, A G; De Gerone, M; Dequal, D; Dermenev, A; Dolfini, R; Dussoni, S; Farnese, C; Fava, A; Ferrari, A; Fiorillo, G; Garvey, G T; Gatti, F; Gibin, D; Gigli Berzolari, A; Gninenko, S; Guber, F; Guglielmi, A; Haranczyk, M; Holeczek, J; Ivashkin, A; Kirsanov, M; Kisiel, J; Kochanek, I; Kurepin, A; Łagoda, J; Louis, W C; Lucchini, G; Mania, S; Mannocchi, G; Matveev, V; Menegolli, A; Meng, G; Mills, G B; Montanari, C; Otwinowski, S; Palczewski, T J; Perfetto, F; Periale, L; Picchi, P; Pietropaolo, F; Płoński, P; Rappoldi, A; Raselli, G L; Rossella, M; Sala, P; Scantamburlo, E; Scaramelli, A; Segreto, E; Sergiampietri, F; Suvorova, O; Stefan, D; Stepaniak, J; Sulej, R; Terrani, M; Testera, G; Tlisov, D; Trinchero, G; Van de Water, R G; Varanini, F; Ventura, S; Vignoli, C; Wang, H G; Yang, X; Zani, A; Zaremba, K

2011-01-01

The present proposal describes an experimental search of sterile neutrinos beyond the Standard Model with the CERN-PS beam and the innovative technology of imaging in ultra-pure cryogenic liquid Argon. The proposal is based on two strictly identical LAr-TPC detectors observing the electron-neutrino signal in the ”Far” and “Near” positions, the first one of about 600 tons placed 850 m the second one of about 150 tons at about 6.5 times shorter distance from the proton target. This project will exploit the ICARUS T600 — now running in the underground experiment CNGS2 with neutrinos from the CERN-SPS — moved from GranSasso to the CERN “Far” position. The additional T150 will be constructed and located in the “Near” position. In the two positions, the radial and energy spectra of the nu_e beam are practically identical. Comparing the two detectors, in absence of oscillations, all cross sections and experimental biases cancel out and the two experimentally observed event distributions must be ...

Chemical abundances of 1111 FGK stars from the HARPS GTO planet search program. II. Cu, Zn, Sr, Y, Zr, Ba, Ce, Nd, and Eu

Science.gov (United States)

Delgado Mena, E.; Tsantaki, M.; Adibekyan, V. Zh.; Sousa, S. G.; Santos, N. C.; González Hernández, J. I.; Israelian, G.

2017-10-01

opposite trend found for thick disc stars suggests that intermediate-mass AGB stars play an important role in the enrichment of the gas from where these stars formed. Previous works in the literature also point to a possible primary production of light-s elements at low metallicities to explain this trend. Finally, we also find an enhancement of light-s elements in the thin disc at super-solar metallicities which could be caused by the contribution of metal-rich AGB stars. Conclusions: This work proves the utility of homogeneous and high-quality data of modest sample sizes. We find some interesting trends that might help to differentiate thin and thick disc population (such as [Zn/Fe] and [Eu/Fe] ratios) and that can also provide useful constraints for Galactic chemical evolution models of the different populations in the Galaxy. Based on observations collected at the La Silla Observatory, ESO (Chile), with the HARPS spectrograph at the 3.6 m ESO telescope (ESO runs ID 72.C—0488, 082.C—0212, and 085.C—0063).Full Tables 1 and 3 are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/606/A94

Scintillator high-gain avalanche rushing photoconductor active-matrix flat panel imager: zero-spatial frequency x-ray imaging properties of the solid-state SHARP sensor structure.

Science.gov (United States)

Wronski, M; Zhao, W; Tanioka, K; Decrescenzo, G; Rowlands, J A

2012-11-01

The authors are investigating the feasibility of a new type of solid-state x-ray imaging sensor with programmable avalanche gain: scintillator high-gain avalanche rushing photoconductor active matrix flat panel imager (SHARP-AMFPI). The purpose of the present work is to investigate the inherent x-ray detection properties of SHARP and demonstrate its wide dynamic range through programmable gain. A distributed resistive layer (DRL) was developed to maintain stable avalanche gain operation in a solid-state HARP. The signal and noise properties of the HARP-DRL for optical photon detection were investigated as a function of avalanche gain both theoretically and experimentally, and the results were compared with HARP tube (with electron beam readout) used in previous investigations of zero spatial frequency performance of SHARP. For this new investigation, a solid-state SHARP x-ray image sensor was formed by direct optical coupling of the HARP-DRL with a structured cesium iodide (CsI) scintillator. The x-ray sensitivity of this sensor was measured as a function of avalanche gain and the results were compared with the sensitivity of HARP-DRL measured optically. The dynamic range of HARP-DRL with variable avalanche gain was investigated for the entire exposure range encountered in radiography∕fluoroscopy (R∕F) applications. The signal from HARP-DRL as a function of electric field showed stable avalanche gain, and the noise associated with the avalanche process agrees well with theory and previous measurements from a HARP tube. This result indicates that when coupled with CsI for x-ray detection, the additional noise associated with avalanche gain in HARP-DRL is negligible. The x-ray sensitivity measurements using the SHARP sensor produced identical avalanche gain dependence on electric field as the optical measurements with HARP-DRL. Adjusting the avalanche multiplication gain in HARP-DRL enabled a very wide dynamic range which encompassed all clinically relevant

Scintillator high-gain avalanche rushing photoconductor active-matrix flat panel imager: Zero-spatial frequency x-ray imaging properties of the solid-state SHARP sensor structure

International Nuclear Information System (INIS)

Wronski, M.; Zhao, W.; Tanioka, K.; DeCrescenzo, G.; Rowlands, J. A.

2012-01-01

Purpose: The authors are investigating the feasibility of a new type of solid-state x-ray imaging sensor with programmable avalanche gain: scintillator high-gain avalanche rushing photoconductor active matrix flat panel imager (SHARP-AMFPI). The purpose of the present work is to investigate the inherent x-ray detection properties of SHARP and demonstrate its wide dynamic range through programmable gain. Methods: A distributed resistive layer (DRL) was developed to maintain stable avalanche gain operation in a solid-state HARP. The signal and noise properties of the HARP-DRL for optical photon detection were investigated as a function of avalanche gain both theoretically and experimentally, and the results were compared with HARP tube (with electron beam readout) used in previous investigations of zero spatial frequency performance of SHARP. For this new investigation, a solid-state SHARP x-ray image sensor was formed by direct optical coupling of the HARP-DRL with a structured cesium iodide (CsI) scintillator. The x-ray sensitivity of this sensor was measured as a function of avalanche gain and the results were compared with the sensitivity of HARP-DRL measured optically. The dynamic range of HARP-DRL with variable avalanche gain was investigated for the entire exposure range encountered in radiography/fluoroscopy (R/F) applications. Results: The signal from HARP-DRL as a function of electric field showed stable avalanche gain, and the noise associated with the avalanche process agrees well with theory and previous measurements from a HARP tube. This result indicates that when coupled with CsI for x-ray detection, the additional noise associated with avalanche gain in HARP-DRL is negligible. The x-ray sensitivity measurements using the SHARP sensor produced identical avalanche gain dependence on electric field as the optical measurements with HARP-DRL. Adjusting the avalanche multiplication gain in HARP-DRL enabled a very wide dynamic range which encompassed all

Development and tests of an anode readout TPC with high track separability for large solid angle relativistic ion experiments

International Nuclear Information System (INIS)

Lindenbaum, S.J.; Foley, K.J.; Eiseman, S.E.

1988-01-01

We have developed, constructed and tested an anode readout TPC with high track separability which is suitable for large solid angle relativistic ion experiments. The readout via rows of short anode wires parallel to the beam has been found in tests to allow two-track separability of ∼2-3 mm. The efficiency of track reconstruction for events from a target, detected inside the MPS 5 KG magnet, is estimated to be >90% for events made by incident protons and pions. 15 GeV/c x A Si ion beams at a rate of ∼25 K per AGS pulse were permitted to course through the chamber and did not lead to any problems. When the gain was reduced to simulate the total output of a minimum ionizing particle, many Si ion tracks were also detected simultaneously with high efficiency. The resolution along the drift direction (parallel to the MPS magnetic field and perpendicular to the beam direction) was <1 mm and the resolution along the other direction /perpendicular/ to the beam direction was <1 mm also. 3 refs., 5 figs

The GAPS programme with HARPS-N at TNG. X. Differential abundances in the XO-2 planet-hosting binary

Science.gov (United States)

Biazzo, K.; Gratton, R.; Desidera, S.; Lucatello, S.; Sozzetti, A.; Bonomo, A. S.; Damasso, M.; Gandolfi, D.; Affer, L.; Boccato, C.; Borsa, F.; Claudi, R.; Cosentino, R.; Covino, E.; Knapic, C.; Lanza, A. F.; Maldonado, J.; Marzari, F.; Micela, G.; Molaro, P.; Pagano, I.; Pedani, M.; Pillitteri, I.; Piotto, G.; Poretti, E.; Rainer, M.; Santos, N. C.; Scandariato, G.; Zanmar Sanchez, R.

2015-11-01

Binary stars hosting exoplanets are a unique laboratory where chemical tagging can be performed to measure the elemental abundances of both stellar components with high accuracy, with the aim to investigate the formation of planets and their subsequent evolution. Here, we present a high-precision differential abundance analysis of the XO-2 wide stellar binary based on high-resolution HARPS-N at TNG spectra. Both components are very similar K-dwarfs and host planets. Since they formed presumably within the same molecular cloud, we expect that they possess the same initial elemental abundances. We investigated whether planets can cause some chemical imprints in the stellar atmospheric abundances. We measure abundances of 25 elements for both stars with a range of condensation temperature TC = 40-1741 K, achieving typical precisions of ~0.07 dex. The northern component shows abundances in all elements higher by +0.067 ± 0.032 dex on average, with a mean difference of +0.078 dex for elements with TC > 800 K. The significance of the XO-2N abundance difference relative to XO-2S is at the 2σ level for almost all elements. We discuss that this result might be interpreted as the signature of the ingestion of material by XO-2N or depletion in XO-2S that is due to locking of heavy elements by the planetary companions. We estimate a mass of several tens of M⊕ in heavy elements. The difference in abundances between XO-2N and XO-2S shows a positive correlation with the condensation temperatures of the elements, with a slope of (4.7 ± 0.9) × 10-5 dex K-1, which could mean that both components have not formed terrestrial planets, but first experienced the accretion of rocky core interior to the subsequent giant planets. Based on observations made with the Italian Telescopio Nazionale Galileo (TNG), operated on the island of La Palma by the INAF - Fundación Galileo Galilei at the Roche de los Muchachos Observatory of the Instituto de Astrofísica de Canarias (IAC) in the

Study on ECH-assisted start-up using trapped particle configuration in KSTAR and application to ITER

Science.gov (United States)

Lee, Jeongwon; Kim, Jayhyun; An, YoungHwa; Yoo, Min-Gu; Hwang, Y. S.; Na, Yong-Su

2017-12-01

ECH-assisted start-up using trapped particle configuration (TPC) is firstly studied in a superconducting, conventional tokamak, KSTAR. First, improved and efficient start-up using TPC than conventional field null configuration (FNC) is achieved by enhanced pre-ionization plasma quality. TPC shows the broader operation window in terms of the poloidal field quality and the deuterium prefill pressure than that of FNC. Surprisingly the particle trapping enhances the plasma start-up performance even with much lower particle trapping ratio than that of spherical torus. Reliability of TPC with low trapping ratio is investigated by 0D plasma evolution code, TECHP0D. Second, the characteristics of TPC start-up are explored with experiments and modellings. Two kind of start-up failure conditions are identified by the magnetic pitch and prefill pressure scan experiments: (i) low ionization rate; and (ii) low density condition. These experimental observation has consistency with TECHP0D modeling result. Finally, reliable ITER-relevant low toroidal electric field start-up using TPC is achieved with drastically improved success rate of start-up in KSTAR. In this experiments, validity of the ITER-like toroidally inclined ECH/ECCD injection is also expected. Time dependent ITER start-up scenario using TPC is proposed and the superiority of it than FNC is discussed.

Peran Mikoriza Arbuskula pada Insidensi Penyakit Busuk Pangkal Batang Lada

Directory of Open Access Journals (Sweden)

Halim Halim

2017-02-01

Full Text Available Stem rot or foot rot disease caused by Phytophthora capsici is known as an important constraint on pepper cultivation. Research was conducted to determine the effect of arbuskula mycorhizal fungi (AMF on incidence of foot rot disease of pepper seedlings.  The experiment was done in the net house and arranged using completed randomized design with 6 treatments, i.e. (1 soil infested by P. capsici (TPC as negative control treatment, (2 sterilized soil (TS as positive control treatment, (3 TPC with 5 g of AMF, (4 TPC with 10 g AMF, (5 TPC with 15 g AMF, and (6 TPC with 20 g AMF.   Observation involved plant height, number of shoots, disease incidence, the percentage of AMF infection on the roots of pepper plants, and pepper plants dependence on AMF. The results showed that the application of AMF at a dose of 20 g per 10 kg of soil effectively suppressed incidence of foot rot disease and improve plant growth

Additional measures do not improve the diagnostic accuracy of the Hospital Admission Risk Profile for detecting downstream quality of life in community-dwelling older people presenting to a hospital emergency department

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Grimmer K

2014-01-01

Full Text Available K Grimmer, S Milanese, K Beaton, A AtlasInternational Centre for Allied Health Evidence, University of South Australia, Adelaide, SA, AustraliaIntroduction: The Hospital Admission Risk Profile (HARP instrument is commonly used to assess risk of functional decline when older people are admitted to hospital. HARP has moderate diagnostic accuracy (65% for downstream decreased scores in activities of daily living. This paper reports the diagnostic accuracy of HARP for downstream quality of life. It also tests whether adding other measures to HARP improves its diagnostic accuracy.Methods: One hundred and forty-eight independent community dwelling individuals aged 65 years or older were recruited in the emergency department of one large Australian hospital with a medical problem for which they were discharged without a hospital ward admission. Data, including age, sex, primary language, highest level of education, postcode, living status, requiring care for daily activities, using a gait aid, receiving formal community supports, instrumental activities of daily living in the last week, hospitalization and falls in the last 12 months, and mental state were collected at recruitment. HARP scores were derived from a formula that summed scores assigned to age, activities of daily living, and mental state categories. Physical and mental component scores of a quality of life measure were captured by telephone interview at 1 and 3 months after recruitment.Results: HARP scores are moderately accurate at predicting downstream decline in physical quality of life, but did not predict downstream decline in mental quality of life. The addition of other variables to HARP did not improve its diagnostic accuracy for either measure of quality of life.Conclusion: HARP is a poor predictor of quality of life.Keywords: functional decline, HARP, quality of life, older people

The EADC-ADNI Harmonized Protocol for manual hippocampal segmentation on magnetic resonance: Evidence of validity

Science.gov (United States)

Frisoni, Giovanni B.; Jack, Clifford R.; Bocchetta, Martina; Bauer, Corinna; Frederiksen, Kristian S.; Liu, Yawu; Preboske, Gregory; Swihart, Tim; Blair, Melanie; Cavedo, Enrica; Grothe, Michel J.; Lanfredi, Mariangela; Martinez, Oliver; Nishikawa, Masami; Portegies, Marileen; Stoub, Travis; Ward, Chadwich; Apostolova, Liana G.; Ganzola, Rossana; Wolf, Dominik; Barkhof, Frederik; Bartzokis, George; DeCarli, Charles; Csernansky, John G.; deToledo-Morrell, Leyla; Geerlings, Mirjam I.; Kaye, Jeffrey; Killiany, Ronald J.; Lehéricy, Stephane; Matsuda, Hiroshi; O'Brien, John; Silbert, Lisa C.; Scheltens, Philip; Soininen, Hilkka; Teipel, Stefan; Waldemar, Gunhild; Fellgiebel, Andreas; Barnes, Josephine; Firbank, Michael; Gerritsen, Lotte; Henneman, Wouter; Malykhin, Nikolai; Pruessner, Jens C.; Wang, Lei; Watson, Craig; Wolf, Henrike; deLeon, Mony; Pantel, Johannes; Ferrari, Clarissa; Bosco, Paolo; Pasqualetti, Patrizio; Duchesne, Simon; Duvernoy, Henri; Boccardi, Marina

2015-01-01

Background An international Delphi panel has defined a harmonized protocol (HarP) for the manual segmentation of the hippocampus on MR. The aim of this study is to study the concurrent validity of the HarP toward local protocols, and its major sources of variance. Methods Fourteen tracers segmented 10 Alzheimer's Disease Neuroimaging Initiative (ADNI) cases scanned at 1.5 T and 3T following local protocols, qualified for segmentation based on the HarP through a standard web-platform and resegmented following the HarP. The five most accurate tracers followed the HarP to segment 15 ADNI cases acquired at three time points on both 1.5 T and 3T. Results The agreement among tracers was relatively low with the local protocols (absolute left/right ICC 0.44/0.43) and much higher with the HarP (absolute left/right ICC 0.88/0.89). On the larger set of 15 cases, the HarP agreement within (left/right ICC range: 0.94/0.95 to 0.99/0.99) and among tracers (left/right ICC range: 0.89/0.90) was very high. The volume variance due to different tracers was 0.9% of the total, comparing favorably to variance due to scanner manufacturer (1.2), atrophy rates (3.5), hemispheric asymmetry (3.7), field strength (4.4), and significantly smaller than the variance due to atrophy (33.5%, P < .001), and physiological variability (49.2%, P < .001). Conclusions The HarP has high measurement stability compared with local segmentation protocols, and good reproducibility within and among human tracers. Hippocampi segmented with the HarP can be used as a reference for the qualification of human tracers and automated segmentation algorithms. PMID:25267715

In vitro mechanical evaluation of a novel pin-sleeve system for external fixation of distal limb fractures in horses: a proof of concept study.

Science.gov (United States)

Brianza, Stefano; Brighenti, Vittoria; Boure, Ludovic; Sprenger, Victor; Pearce, Simon; Schwieger, Karsten

2010-07-01

To evaluate the efficacy of a novel pin-sleeve cast (PSC) system for external fixation of distal limb fractures in horses and to compare it with the transfixation pin cast (TPC) system. Experimental. One bone substitute each was used for the TPC and PSC systems. The PSC was tested in 4 configurations characterized by different pin preloads. Specimens were loaded in axial compression in the elastic range. Variables compared statistically were: bone substitute axial displacement and axial strain measured above implants with strain gauges. Pin preload was correlated with the variables investigated. Load to failure and a fatigue tests supplemented the investigation. The PSC configuration with the highest pin preload showed a significantly lower axial displacement compared with the TPC. No significant differences were observed between all other PSC configurations and the TPC. All PSC systems had a significant decrease in recorded strain compared with the TPC system. Pin axial preload inversely correlated with axial displacement but had no effect on axial strain. In the failure test, the PSC encountered plastic deformation earlier than the TPC. In the fatigue test, the PSC ran >200,000 cycles. Preliminary in vitro tests showed that the PSC system significantly reduced peri-implant strain while concurrently having comparable axial displacement to the TPC system. The PSC system has the potential to reduce the risk of pin loosening in horses.

Additional measures do not improve the diagnostic accuracy of the Hospital Admission Risk Profile for detecting downstream quality of life in community-dwelling older people presenting to a hospital emergency department.

Science.gov (United States)

Grimmer, K; Milanese, S; Beaton, K; Atlas, A

2014-01-01

The Hospital Admission Risk Profile (HARP) instrument is commonly used to assess risk of functional decline when older people are admitted to hospital. HARP has moderate diagnostic accuracy (65%) for downstream decreased scores in activities of daily living. This paper reports the diagnostic accuracy of HARP for downstream quality of life. It also tests whether adding other measures to HARP improves its diagnostic accuracy. One hundred and forty-eight independent community dwelling individuals aged 65 years or older were recruited in the emergency department of one large Australian hospital with a medical problem for which they were discharged without a hospital ward admission. Data, including age, sex, primary language, highest level of education, postcode, living status, requiring care for daily activities, using a gait aid, receiving formal community supports, instrumental activities of daily living in the last week, hospitalization and falls in the last 12 months, and mental state were collected at recruitment. HARP scores were derived from a formula that summed scores assigned to age, activities of daily living, and mental state categories. Physical and mental component scores of a quality of life measure were captured by telephone interview at 1 and 3 months after recruitment. HARP scores are moderately accurate at predicting downstream decline in physical quality of life, but did not predict downstream decline in mental quality of life. The addition of other variables to HARP did not improve its diagnostic accuracy for either measure of quality of life. HARP is a poor predictor of quality of life.

THREE PLANETS ORBITING WOLF 1061

Energy Technology Data Exchange (ETDEWEB)

Wright, D. J.; Wittenmyer, R. A.; Tinney, C. G.; Bentley, J. S.; Zhao, Jinglin, E-mail: duncan.wright@unsw.edu.au [Department of Astronomy and Australian Centre for Astrobiology, School of Physics, University of New South Wales, NSW 2052 (Australia)

2016-02-01

We use archival HARPS spectra to detect three planets orbiting the M3 dwarf Wolf 1061 (GJ 628). We detect a 1.36 M{sub ⊕} minimum-mass planet with an orbital period P = 4.888 days (Wolf 1061b), a 4.25 M{sub ⊕} minimum-mass planet with orbital period P = 17.867 days (Wolf 1061c), and a likely 5.21 M{sub ⊕} minimum-mass planet with orbital period P = 67.274 days (Wolf 1061d). All of the planets are of sufficiently low mass that they may be rocky in nature. The 17.867 day planet falls within the habitable zone for Wolf 1061 and the 67.274 day planet falls just outside the outer boundary of the habitable zone. There are no signs of activity observed in the bisector spans, cross-correlation FWHMs, calcium H and K indices, NaD indices, or Hα indices near the planetary periods. We use custom methods to generate a cross-correlation template tailored to the star. The resulting velocities do not suffer the strong annual variation observed in the HARPS DRS velocities. This differential technique should deliver better exploitation of the archival HARPS data for the detection of planets at extremely low amplitudes.

Association Between Hospital Admission Risk Profile Score and Skilled Nursing or Acute Rehabilitation Facility Discharges in Hospitalized Older Adults.

Science.gov (United States)

Liu, Stephen K; Montgomery, Justin; Yan, Yu; Mecchella, John N; Bartels, Stephen J; Masutani, Rebecca; Batsis, John A

2016-10-01

To evaluate whether the Hospital Admission Risk Profile (HARP) score is associated with skilled nursing or acute rehabilitation facility discharge after an acute hospitalization. Retrospective cohort study. Inpatient unit of a rural academic medical center. Hospitalized individuals aged 70 and older from October 1, 2013 to June 1, 2014. Participant age at the time of admission, modified Folstein Mini-Mental State Examination score, and self-reported instrumental activities of daily living 2 weeks before admission were used to calculate HARP score. The primary predictor was HARP score, and the primary outcome was discharge disposition (home, facility, deceased). Multivariate analysis was used to evaluate the association between HARP score and discharge disposition, adjusting for age, sex, comorbidities, and length of stay. Four hundred twenty-eight individuals admitted from home were screened and their HARP scores were categorized as low (n = 162, 37.8%), intermediate (n = 157, 36.7%), or high (n = 109, 25.5%). Participants with high HARP scores were significantly more likely to be discharged to a facility (55%) than those with low HARP scores (20%) (P risk of skilled nursing or acute rehabilitation facility discharge. Early identification for potential facility discharges may allow for targeted interventions to prevent functional decline, improve informed shared decision-making about post-acute care needs, and expedite discharge planning. © 2016, Copyright the Authors Journal compilation © 2016, The American Geriatrics Society.

First operation and performance of a 200 lt double phase LAr LEM-TPC with a 40x76 $\\cm^2$ readout

CERN Document Server

Badertscher, A; Degunda, U; Epprecht, L; Gendotti, A; Horikawa, S; Knecht, L; Natterer, D Lussi G; Nguyen, K; Resnati, F; Rubbia, A; Viant, T

2013-01-01

In this paper we describe the design, construction, and operation of a first large area double-phase liquid argon Large Electron Multiplier Time Projection Chamber (LAr LEM-TPC). The detector has a maximum drift length of 60 cm and the readout consists of a $40\\times 76$ cm$^2$ LEM and 2D projective anode to multiply and collect drifting charges. Scintillation light is detected by means of cryogenic PMTs positioned below the cathode. To record both charge and light signals, we have developed a compact acquisition system, which is scalable up to ton-scale detectors with thousands of charge readout channels. The acquisition system, as well as the design and the performance of custom-made charge sensitive preamplifiers, are described. The complete experimental setup has been operated for a first time during a period of four weeks at CERN in the cryostat of the ArDM experiment, which was equipped with liquid and gas argon purification systems. The detector, exposed to cosmic rays, recorded events with a single-ch...

Single-phase ProtoDUNE, the Prototype of a Single-Phase Liquid Argon TPC for DUNE at the CERN Neutrino Platform

CERN Document Server

Cavanna, F; Touramanis, C

2017-01-01

ProtoDUNE-SP is the single-phase DUNE Far Detector prototype that is under construction and will be operated at the CERN Neutrino Platform (NP) starting in 2018. It was proposed to the CERN SPSC in June 2015 (SPSC-P-351) and was approved in December 2015 as experiment NP04 (ProtoDUNE). ProtoDUNE-SP, a crucial part of the DUNE effort towards the construction of the first DUNE 10-kt fiducial mass far detector module (17 kt total LAr mass), is a significant experiment in its own right. With a total liquid argon (LAr) mass of 0.77 kt, it represents the largest monolithic single phase LArTPC detector to be built to date. It is housed in an extension to the EHN1 hall in the North Area, where the CERN NP is providing a new dedicated charged-particle test beamline. ProtoDUNE-SP aims to take its first beam data before the LHC long shutdown (LS2) at the end of 2018. ProtoDUNE-SP prototypes the designs of most of the single-phase DUNE far detector module (DUNE-SP) components at a 1:1 scale, with an extrapolation of abo...

Photosynthetic capacity of 'Niagara Rosada' grapes grown under transparent plastic covering

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Bruna Corrêa da Silva de Deus

2016-06-01

Full Text Available ABSTRACT: New techniques in tropical regions such as use of transparent plastic covering (TPC, have been employed in grapes to avoid the wetting leaves and fruits, which can reduce the occurrence of fungal diseases, reduce the use of sprays, and reduce damage caused by hail and high winds. TPC may significantly affect the photosynthetic rates of grapevines cultivated in tropical regions, and thus have strong effects on plant productivity and improve fruit quality. However, in the North of Rio de Janeiro region there are lacks of studies related to TPC effects on photosynthetic capacity. The objective of this study was to evaluate the photosynthetic capacity in 'Niagara Rosada' vines grown under TPC and without transparent plastic covering (WTPC. The experiment was conducted between April and June 2013, on Tabuinha farm, located in the 3rd district of São Fidélis, Rio de Janeiro State, Brazil. A completely randomized block design was used with two treatments (TPC and WTPC and twelve replications. Evaluations consisted of climatological variables, gas exchange and maximum quantum efficiency of open photosystem II centers-quantum yield (Fv/Fm It was possible to observe that under TPC maximum temperature increase of 2.3°C, relative humidity reduced 1.5%, vapor pressure deficit increase 0.4kPa, and light intensity reduced 47.7%. These changes did not cause photochemical damage to the leaves. The TPC promoted higher net photosynthetic rate at 800h, which was associated with higher stomatal conductance. Thus, the TPC used in the northern region of Rio de Janeiro State did not impair the photosynthetic capacity of 'Niagara Rosada' vines.

Numerical Study of Electrostatic Field Distortion on LPTPC End-Plates based on Bulk Micromegas Modules

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Bhattacharya Purba

2018-01-01

Full Text Available The R&D activities for the linear collider TPC (LC-TPC are currently working on the adoption of the micro pattern devices for the gaseous amplification stage. Several beam tests have been carried out at DESY with a 5 GeV electron beam in a 1 T superconducting magnet. We worked on a large prototype TPC with an end-plate that was built, for the first time, using seven resistive bulk Micromegas modules. During experiments, reduced signal sensitivity was observed at the boundary of these modules. Electrostatic field distortion near the module boundaries was considered to be the possible major reason behind these observations. In the present work, we will explore this hypothesis through numerical simulation. Our aim has been to understand the origin of distortions observed close to the edges of the test beam modules and to explore the possibility of using the Garfield simulation framework for investigating a phenomenon as complex as distortion.

Near-intrinsic energy resolution for 30–662 keV gamma rays in a high pressure xenon electroluminescent TPC

International Nuclear Information System (INIS)

Álvarez, V.; Borges, F.I.G.M.; Cárcel, S.; Castel, J.; Cebrián, S.; Cervera, A.; Conde, C.A.N.; Dafni, T.; Dias, T.H.V.T.; Díaz, J.

2013-01-01

We present the design, data and results from the NEXT prototype for Double Beta and Dark Matter (NEXT-DBDM) detector, a high-pressure gaseous natural xenon electroluminescent time projection chamber (TPC) that was built at the Lawrence Berkeley National Laboratory. It is a prototype of the planned NEXT-100 136 Xe neutrino-less double beta decay (0νββ) experiment with the main objectives of demonstrating near-intrinsic energy resolution at energies up to 662 keV and of optimizing the NEXT-100 detector design and operating parameters. Energy resolutions of ∼1% FWHM for 662 keV gamma rays were obtained at 10 and 15 atm and ∼5% FWHM for 30 keV fluorescence xenon X-rays. These results demonstrate that 0.5% FWHM resolutions for the 2459 keV hypothetical neutrino-less double beta decay peak are realizable. This energy resolution is a factor 7–20 better than that of the current leading 0νββ experiments using liquid xenon and thus represents a significant advancement. We present also first results from a track imaging system consisting of 64 silicon photo-multipliers recently installed in NEXT–DBDM that, along with the excellent energy resolution, demonstrates the key functionalities required for the NEXT-100 0νββ search

MO-AB-BRA-07: Low Dose Imaging with Avalanche Amorphous Selenium Flat Panel Imager

Energy Technology Data Exchange (ETDEWEB)

Scheuermann, J; Howansky, A; Goldan, A; Tanioka, K; Zhao, W [Stony Brook University, Stony Brook, New York (United States); Leveille, S; Tousignant, O [2Analogic Canada, Saint-laurent, Quebec (Canada)

2016-06-15

Purpose: We present the first active matrix flat panel imager (AMFPI) capable of producing x-ray quantum noise limited images at low doses by overcoming the electronic noise through signal amplification by photoconductive avalanche gain (gav). The indirect detector fabricated uses an optical sensing layer of amorphous selenium (a-Se) known as High-Gain Avalanche Rushing Photoconductor (HARP). The detector design is called Scintillator HARP (SHARP)-AMFPI. This is the first image sensor to utilize solid-state HARP technology. Methods: The detector’s electronic readout is a 24 × 30 cm{sup 2} array of thin film transistors (TFT) with a pixel pitch of 85 µm. The HARP structure consists of a 15 µm layer of a-Se isolated from the high voltage (HV) and signal electrode by a 2 µm thick hole blocking layer and electron blocking layer, respectively, to reduce dark current. A 150 µm thick structured CsI scintillator with reflective backing and a fiber optic faceplate (FOP) was coupled to the semi-transparent HV bias electrode of the HARP structure. Images were acquired using a 30 kVp Mo/Mo spectrum typically used in mammography. Results: Optical sensitivity measurements demonstrate that gav = 76 ± 5 can be achieved over the entire active area of the detector. At a constant dose to the detector of 6.67 µGy, image quality increases with gav until the effective electronic noise is negligible. Quantum noise limited images can be obtained with doses as low as 0.18 µGy. Conclusion: We demonstrate the feasibility of utilizing avalanche gain to overcome electronic noise. The indirect detector fabricated is the first solid-state imaging sensor to use HARP, and the largest active area HARP sensor to date. Our future work is to improve charge transport within the HARP structure and utilize a transparent HV electrode.

Changing the model of care delivery: nurses' perceptions of job satisfaction and care effectiveness.

Science.gov (United States)

Wells, Judith; Manuel, Madonna; Cunning, Glenda

2011-09-01

To examine nurses' perceptions of job satisfaction, empowerment, and care effectiveness following a change from team to a modified total patient care (TPC) delivery model. Empirical data related to TPC is limited and inconclusive. Similarly, evidence demonstrating nurses' experience with change and restructuring is limited. A mixed method, longitudinal, descriptive design was used. Registered nurses and licenced practical nurses in two acute-care nursing units completed quantitative and qualitative surveys. Lewin's change theory provided the framework for the study. No significant change in job satisfaction was observed; however, it was less than optimal at all three time-periods. Nurses were committed to their jobs but relatively dissatisfied with their input into the goals and processes of the organization. Client care was perceived to be more effective under TPC. Job satisfaction remained consistent following the transition to TPC. However, nurses perceived that client care within the modified TPC model was more effective than in the previous model. Nursing administration must work collaboratively with nurses to improve processes in nursing practice that could enhance nurses' job satisfaction and improve client care delivery. 2011 Blackwell Publishing Ltd.

ESA Atmospheric Toolbox

Science.gov (United States)

Niemeijer, Sander

2017-04-01

The ESA Atmospheric Toolbox (BEAT) is one of the ESA Sentinel Toolboxes. It consists of a set of software components to read, analyze, and visualize a wide range of atmospheric data products. In addition to the upcoming Sentinel-5P mission it supports a wide range of other atmospheric data products, including those of previous ESA missions, ESA Third Party missions, Copernicus Atmosphere Monitoring Service (CAMS), ground based data, etc. The toolbox consists of three main components that are called CODA, HARP and VISAN. CODA provides interfaces for direct reading of data from earth observation data files. These interfaces consist of command line applications, libraries, direct interfaces to scientific applications (IDL and MATLAB), and direct interfaces to programming languages (C, Fortran, Python, and Java). CODA provides a single interface to access data in a wide variety of data formats, including ASCII, binary, XML, netCDF, HDF4, HDF5, CDF, GRIB, RINEX, and SP3. HARP is a toolkit for reading, processing and inter-comparing satellite remote sensing data, model data, in-situ data, and ground based remote sensing data. The main goal of HARP is to assist in the inter-comparison of datasets. By appropriately chaining calls to HARP command line tools one can pre-process datasets such that two datasets that need to be compared end up having the same temporal/spatial grid, same data format/structure, and same physical unit. The toolkit comes with its own data format conventions, the HARP format, which is based on netcdf/HDF. Ingestion routines (based on CODA) allow conversion from a wide variety of atmospheric data products to this common format. In addition, the toolbox provides a wide range of operations to perform conversions on the data such as unit conversions, quantity conversions (e.g. number density to volume mixing ratios), regridding, vertical smoothing using averaging kernels, collocation of two datasets, etc. VISAN is a cross-platform visualization and

Tuning the ion selectivity of two-pore channels

Energy Technology Data Exchange (ETDEWEB)

Guo, Jiangtao; Zeng, Weizhong; Jiang, Youxing (UTSMC)

2017-01-17

Organellar two-pore channels (TPCs) contain two copies of a Shaker-like six-transmembrane (6-TM) domain in each subunit and are ubiquitously expressed in plants and animals. Interestingly, plant and animal TPCs share high sequence similarity in the filter region, yet exhibit drastically different ion selectivity. Plant TPC1 functions as a nonselective cation channel on the vacuole membrane, whereas mammalian TPC channels have been shown to be endo/lysosomal Na+-selective or Ca2+-release channels. In this study, we performed systematic characterization of the ion selectivity of TPC1 from Arabidopsis thaliana (AtTPC1) and compared its selectivity with the selectivity of human TPC2 (HsTPC2). We demonstrate that AtTPC1 is selective for Ca2+ over Na+, but nonselective among monovalent cations (Li+, Na+, and K+). Our results also confirm that HsTPC2 is a Na+-selective channel activated by phosphatidylinositol 3,5-bisphosphate. Guided by our recent structure of AtTPC1, we converted AtTPC1 to a Na+-selective channel by mimicking the selectivity filter of HsTPC2 and identified key residues in the TPC filters that differentiate the selectivity between AtTPC1 and HsTPC2. Furthermore, the structure of the Na+-selective AtTPC1 mutant elucidates the structural basis for Na+ selectivity in mammalian TPCs.

Ultrasound assisted extraction of polyphenols and their distribution in whole mung bean, hull and cotyledon.

Science.gov (United States)

Singh, Barinderjit; Singh, Narpinder; Thakur, Sheetal; Kaur, Amritpal

2017-03-01

In this study, extraction of polyphenols using different solvents (acetone, ethanol, methanol and water) with ultrasound and conventional method from whole mung bean (WMB), hull and cotyledon was conducted. Total phenolic content (TPC), total flavonoids content (TFC), total antioxidant activities (TAA), ferric reducing power (FRP) and DPPH radical scavenging activity were determined. Ultrasound treated extracts exhibited higher TPC, TFC, TAA, FRP and DPPH in different mung bean fractions than CSE. Among the solvents, acetone showed better TPC, TFC, TAA, FRP and DPPH. Hull had significantly higher TPC, TFC, TAA, FRP and DPPH than WMB and cotyledon. Sinapic acid (SA) was the major polyphenol in different fractions. Acetone extract of hull showed high polyphenol content. SA, ferulic acid, catechin, p-coumaric acid, resveratrol, quercetin and luteolin were the major contributors to antioxidant activity of acetone extract. Mung bean hull contained the maximum polyphenols and acetone was observed to be the best extraction medium for polyphenols in combination with ultrasound.

Using synchrotron radiation angiography with a highly sensitive detector to identify impaired peripheral perfusion in rat pulmonary emphysema

Energy Technology Data Exchange (ETDEWEB)

Ito, Hiromichi [University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575 (Japan); Matsushita, Shonosuke, E-mail: shomatsu@md.tsukuba.ac.jp [University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575 (Japan); Tsukuba University of Technology, Tsukuba, Ibaraki 305-8521 (Japan); Hyodo, Kazuyuki [High Energy Accelerator Research Organization, KEK, Tsukuba, Ibaraki 305-0801 (Japan); Sato, Yukio; Sakakibara, Yuzuru [University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575 (Japan)

2013-03-01

Synchrotron radiation angiography with a HARP detector made it possible to evaluate impaired pulmonary microcirculation in pulmonary emphysema by means of high sensitivity. Owing to limitations in spatial resolution and sensitivity, it is difficult for conventional angiography to detect minute changes of perfusion in diffuse lung diseases, including pulmonary emphysema (PE). However, a high-gain avalanche rushing amorphous photoconductor (HARP) detector can give high sensitivity to synchrotron radiation (SR) angiography. SR angiography with a HARP detector provides high spatial resolution and sensitivity in addition to time resolution owing to its angiographic nature. The purpose of this study was to investigate whether this SR angiography with a HARP detector could evaluate altered microcirculation in PE. Two groups of rats were used: group PE and group C (control). Transvenous SR angiography with a HARP detector was performed and histopathological findings were compared. Peak density of contrast material in peripheral lung was lower in group PE than group C (p < 0.01). The slope of the linear regression line in scattering diagrams was also lower in group PE than C (p < 0.05). The correlation between the slope and extent of PE in histopathology showed significant negative correlation (p < 0.05, r = 0.61). SR angiography with a HARP detector made it possible to identify impaired microcirculation in PE by means of its high spatial resolution and sensitivity.

Using synchrotron radiation angiography with a highly sensitive detector to identify impaired peripheral perfusion in rat pulmonary emphysema

International Nuclear Information System (INIS)

Ito, Hiromichi; Matsushita, Shonosuke; Hyodo, Kazuyuki; Sato, Yukio; Sakakibara, Yuzuru

2013-01-01

Synchrotron radiation angiography with a HARP detector made it possible to evaluate impaired pulmonary microcirculation in pulmonary emphysema by means of high sensitivity. Owing to limitations in spatial resolution and sensitivity, it is difficult for conventional angiography to detect minute changes of perfusion in diffuse lung diseases, including pulmonary emphysema (PE). However, a high-gain avalanche rushing amorphous photoconductor (HARP) detector can give high sensitivity to synchrotron radiation (SR) angiography. SR angiography with a HARP detector provides high spatial resolution and sensitivity in addition to time resolution owing to its angiographic nature. The purpose of this study was to investigate whether this SR angiography with a HARP detector could evaluate altered microcirculation in PE. Two groups of rats were used: group PE and group C (control). Transvenous SR angiography with a HARP detector was performed and histopathological findings were compared. Peak density of contrast material in peripheral lung was lower in group PE than group C (p < 0.01). The slope of the linear regression line in scattering diagrams was also lower in group PE than C (p < 0.05). The correlation between the slope and extent of PE in histopathology showed significant negative correlation (p < 0.05, r = 0.61). SR angiography with a HARP detector made it possible to identify impaired microcirculation in PE by means of its high spatial resolution and sensitivity

Application of Ultrasonic Waves on Maintaining Freshness of Tilapia Fillet

Directory of Open Access Journals (Sweden)

Ruddy Suwandi

2015-06-01

Full Text Available ish fillet is one of fisheries products that easily deteriorated; hence handling techniques are needed to maintain the freshness. Ultrasonic wave have been widely applied to some of food products for maintaining freshness through microbial inactivation, however the ultrasonic application to fisheries products has not been reported. The purpose of this study was to analyze the effect of ultrasonic wave on fish freshness. The stages of the study were sample preparation, sonication, freshness parameters examination and histology observation. Ultrasonic wave did not affectthe organoleptic value and the TVB, but affected the pH value and the TPC. The sample in which the TPC value was found significantly different, were further observed after 48 and 96 hours storage. The result showed that the TPC value of sonicated sample for 9 minutes was lower to that of without sonication. Histology analysis showed, however, sonication made the structure of muscle fiber less compact and deformation of myomer was found.

The Laser of the ALICE Time Projection Chamber

CERN Document Server

Renault, G; Westergaard, J; GaardhOJe, J J

2007-01-01

The large TPC ($95 \\mathrm{m}^3$) of the ALICE detector at the CERN LHC was commissioned in summer 2006. The first tracks were observed both from the cosmic ray muons and from the laser rays injected into the TPC. In this article the basic principles of operating the $266 \\mathrm{nm}$ lasers are presented, showing the installation and adjustment of the optical system and describing the control system. To generate the laser tracks, a wide laser beam is split into several hundred narrow beams by fixed micro-mirrors at stable and known positions throughout the TPC. In the drift volume, these narrow beams generate straight tracks at many angles. Here we describe the generation of the first tracks and compare them with simulations.

Wide dynamic range beam profile monitor

International Nuclear Information System (INIS)

Lee, D.M.; Brown, D.; Hardekopf, R.; Bilskie, J.R.; van Dyck, O.B.V.

1985-01-01

An economical harp multiplexer system has been developed to achieve a wide dynamic range. The harp system incorporates a pneumatically actuated harp detector with ceramic boards and carbon wires; a high-sensitivity multiplexer packaged in a double-wide NIM module; and flat, shielded ribbon cable consisting of individual twisted pairs. The system multiplexes 30 wires in each of the x and y planes simultaneously and operates with or without computer control. The system has operated in beams of 100 nA to 1 mA, 1- to 120-Hz repetition rate, with a signal-to-noise ratio of greater than 10/1

32 New Exoplanets Found

Science.gov (United States)

2009-10-01

, which detects small changes in the radial velocity of a star as it wobbles slightly under the gentle gravitational pull from an (unseen) exoplanet, has been most prolific method in the search for exoplanets. In return for building the instrument, the HARPS consortium was granted 100 observing nights per year during a five-year period to carry out one of the most ambitious systematic searches for exoplanets so far implemented worldwide by repeatedly measuring the radial velocities of hundreds of stars that may harbour planetary systems. The programme soon proved very successful. Using HARPS, Mayor's team discovered - among others - in 2004, the first super-Earth (around µ Ara; in 2006, the trio of Neptunes around HD 69830; in 2007, Gliese 581d, the first super Earth in the habitable zone of a small star (eso0722); and in 2009, the lightest exoplanet so far detected around a normal star, Gliese 581e (eso0915). More recently, they found a potentially lava-covered world, with density similar to that of the Earth's (eso0933). "These observations have given astronomers a great insight into the diversity of planetary systems and help us understand how they can form," says team member Nuno Santos. The HARPS consortium was very careful in their selection of targets, with several sub-programmes aimed at looking for planets around solar-like stars, low-mass dwarf stars, or stars with a lower metal content than the Sun. The number of exoplanets known around low-mass stars - so-called M dwarfs - has also dramatically increased, including a handful of super Earths and a few giant planets challenging planetary formation theory. "By targeting M dwarfs and harnessing the precision of HARPS we have been able to search for exoplanets in the mass and temperature regime of super-Earths, some even close to or inside the habitable zone around the star," says co-author Xavier Bonfils. The team found three candidate exoplanets around stars that are metal-deficient. Such stars are thought to be

A Total Pleural Covering for Lymphangioleiomyomatosis Prevents Pneumothorax Recurrence.

Directory of Open Access Journals (Sweden)

Masatoshi Kurihara

Full Text Available Spontaneous pneumothorax is a major and frequently recurrent complication of lymphangioleiomyomatosis (LAM. Despite the customary use of pleurodesis to manage pnenumothorax, the recurrence rate remains high, and accompanying pleural adhesions cause serious bleeding during subsequent lung transplantation. Therefore, we have developed a technique of total pleural covering (TPC for LAM to wrap the entire visceral pleura with sheets of oxidized regenerated cellulose (ORC mesh, thereby reinforcing the affected visceral pleura and preventing recurrence.Since January 2003, TPC has been applied during video-assisted thoracoscopic surgery for the treatment of LAM. The medical records of LAM patients who had TPC since that time and until August 2014 are reviewed.TPC was performed in 43 LAM patients (54 hemithoraces, 11 of whom required TPC bilaterally. Pneumothorax recurred in 14 hemithoraces (25.9% from 11 patients (25.6% after TPC. Kaplan-Meier estimates of recurrence-free hemithorax were 80.8% at 2.5 years, 71.7% at 5 years, 71.7% at 7.5 years, and 61.4% at 9 years. The recurrence-free probability was significantly better when 10 or more sheets of ORC mesh were utilized for TPC (P = 0.0018. TPC significantly reduced the frequency of pneumothorax: 0.544 ± 0.606 episode/month (mean ± SD before TPC vs. 0.008 ± 0.019 after TPC (P<0.0001. Grade IIIa postoperative complications were found in 13 TPC surgeries (24.1%.TPC successfully prevented the recurrence of pneumothorax in LAM, was minimally invasive and rarely caused restrictive ventilatory impairment.

Seismic analysis of HD 43587Aa, a solar-like oscillator in a multiple system

NARCIS (Netherlands)

Boumier, P.; Benomar, O.; Baudin, F.; Verner, G.; Appourchaux, T.; Lebreton, Y.; Gaulme, P.; Chaplin, W.; García, R.A.; Hekker, S.; Regulo, C.; Salabert, D.; Stahn, T.; Elsworth, Y.; Gizon, L.; Hall, M.; Mathur, S.; Michel, E.; Morel, T.; Mosser, B.; Poretti, E.; Rainer, M.; Roxburgh, I.; do Nascimento Jr., J.D.; Samadi, R.; Auvergne, M.; Chaintreuil, S.; Baglin, A.; Catala, C.

2014-01-01

Context. The object HD 43587Aa is a G0V star observed during the 145-day LRa03 run of the COnvection, ROtation and planetary Transits space mission (CoRoT), for which complementary High Accuracy Radial velocity Planet Searcher (HARPS) spectra with S/N > 300 were also obtained. Its visual magnitude

The EADC-ADNI Harmonized Protocol for manual hippocampal segmentation on magnetic resonance

DEFF Research Database (Denmark)

Frisoni, Giovanni B; Jack, Clifford R; Bocchetta, Martina

2015-01-01

BACKGROUND: An international Delphi panel has defined a harmonized protocol (HarP) for the manual segmentation of the hippocampus on MR. The aim of this study is to study the concurrent validity of the HarP toward local protocols, and its major sources of variance. METHODS: Fourteen tracers segme...

CoRoT 101186644 : A transiting low-mass dense M-dwarf on an eccentric 20.7-day period orbit around a late F-star. Discovered in the CoRoT lightcurves

NARCIS (Netherlands)

Tal-Or, L.; Mazeh, T.; Alonso, R.; Bouchy, F.; Cabrera, J.; Deeg, H.; Deleuil, M.; Faigler, S.; Fridlund, M.; Hébrard, G.; Moutou, C.; Santerne, A.; Tingley, B.

2013-01-01

We present the study of the CoRoT transiting planet candidate 101186644, also named LRc01_E1_4780. Analysis of the CoRoT lightcurve and the HARPS spectroscopic follow-up observations of this faint (m$_V$ = 16) candidate revealed an eclipsing binary composed of a late F-type primary (T$_{eff}$ = 6090

Effect of Ultrasonic-Assisted Extraction on Phenolic Content of Avocado

International Nuclear Information System (INIS)

Rafidah Husen; Andou, Y.; Amin Ismail; Shirai, Y.

2014-01-01

This study evaluate the effect of ultrasonic application in the extraction process on total phenolic content (TPC) of Hass avocado (Persea americana Mill) pulp. In this study, the solid/ solvent ratio of 1/30 (wt/ vol) and extraction temperature of 40 degree Celsius gave higher TPC value. This ratio and temperature was applied in the ultrasonic-assisted extraction (UAE) of avocado pulp. This study then compared the TPC obtained from the avocado pulp extract without involving ultrasonic and the TPC obtained from the UAE. Results showed that the TPC value of avocado pulp was significantly higher in the UAE (235.77 mg GAE/ 100g dried sample) compared to the TPC in the non-UAE (166.32 mg GAE/ 100g dried sample). The increase in the TPC was between ∼31 % and ∼41 % when 5 to 20 min of ultra sonication applied in the extraction. Ultra sonication duration of 15 min gave the highest TPC where the value was significantly higher compared to the other duration. (author)

The radius and mass of the close solar twin 18 Scorpii derived from asteroseismology and interferometry

DEFF Research Database (Denmark)

Bazot, M.; Ireland, M.J.; Huber, D.

2011-01-01

Sco. We observed the star during 12 nights with HARPS for seismology and used the PAVO beam-combiner at CHARA for interferometry. An average large frequency separation 134.4 ± 0.3 μHz and angular and linear radiuses of 0.6759 ± 0.0062 mas and 1.010 ± 0.009 Rsun were estimated. We used these values...

Two pore channel 2 differentially modulates neural differentiation of mouse embryonic stem cells.

Directory of Open Access Journals (Sweden)

Zhe-Hao Zhang

Full Text Available Nicotinic acid adenine dinucleotide phosphate (NAADP is an endogenous Ca(2+ mobilizing nucleotide presented in various species. NAADP mobilizes Ca(2+ from acidic organelles through two pore channel 2 (TPC2 in many cell types and it has been previously shown that NAADP can potently induce neuronal differentiation in PC12 cells. Here we examined the role of TPC2 signaling in the neural differentiation of mouse embryonic stem (ES cells. We found that the expression of TPC2 was markedly decreased during the initial ES cell entry into neural progenitors, and the levels of TPC2 gradually rebounded during the late stages of neurogenesis. Correspondingly, TPC2 knockdown accelerated mouse ES cell differentiation into neural progenitors but inhibited these neural progenitors from committing to neurons. Overexpression of TPC2, on the other hand, inhibited mouse ES cell from entering the early neural lineage. Interestingly, TPC2 knockdown had no effect on the differentiation of astrocytes and oligodendrocytes of mouse ES cells. Taken together, our data indicate that TPC2 signaling plays a temporal and differential role in modulating the neural lineage entry of mouse ES cells, in that TPC2 signaling inhibits ES cell entry to early neural progenitors, but is required for late neuronal differentiation.

The darkside multiton detector for the direct dark matter search

International Nuclear Information System (INIS)

Aalseth, C. E.; Agnes, P.; Alton, A.; Arisaka, K.; Asner, D. M.; Back, H. O.; Baldin, B.; Biery, K.; Bonfini, G.; Bossa, M.; Brigatti, A.; Brodsky, J.; Budano, F.; Cadonati, L.; Cadoni, M.; Calaprice, F.; Canci, N.; Candela, A.; Cao, H.; Cariello, M.; Cavalcante, P.; Chepurnov, A.; Cocco, A. G.; Condon, C.; Crippa, L.; D'Angelo, D.; D'Incecco, M.; Davini, S.; De Deo, M.; Derbin, A.; Devoto, A.; Di Eusanio, F.; Edkins, E.; Empl, A.; Fan, A.; Fiorillo, G.; Fomenko, K.; Forster, G.; Foxe, M.; Franco, D.; Gabriele, F.; Galbiati, C.; Goretti, A.; Grandi, L.; Gromov, M.; Guan, M. Y.; Guardincerri, Y.; Hackett, B.; Herner, K.; Hime, A.; Humble, P.; Hungerford, E.; Ianni, Al.; Ianni, An.; Jaffe, D. E.; Jollet, C.; Keeter, K.; Kendziora, C.; Kidner, S.; Kobychev, V.; Koh, G.; Korablev, D.; Korga, G.; Kurlej, A.; Li, P. X.; Lissia, M.; Lombardi, P.; Ludhova, L.; Luitz, S.; Lukyachenko, G.; Ma, Y. Q.; Machulin, I.; Mandarano, A.; Mari, S. M.; Maricic, J.; Marini, L.; Markov, D.; Martoff, J.; Meregaglia, A.; Meroni, E.; Meyers, P. D.; Miletic, T.; Milincic, R.; Montuschi, M.; Monzani, M. E.; Mosteiro, P.; Mount, B.; Muratova, V.; Musico, P.; Montanari, D.; Nelson, A.; Odrowski, S.; Odrzywolek, A.; Orrell, J. L.; Orsini, M.; Ortica, F.; Pagani, L.; Pallavicini, M.; Pantic, E.; Parmeggiano, S.; Parsells, B.; Pelczar, K.; Pelliccia, N.; Perasso, S.; Perasso, L.; Pocar, A.; Pordes, S.; Pugachev, D.; Qian, H.; Randle, K.; Ranucci, G.; Razeto, A.; Recine, K.; Reinhold, B.; Renshaw, A.; Romani, A.; Rossi, N.; Rossi, B.; Rountree, S. D.; Sablone, D.; Saggese, P.; Saldanha, R.; Sands, W.; Sangiorgio, S.; Segreto, E.; Semenov, D.; Shields, E.; Skorokhvatov, M.; Smallcomb, M.; Smirnov, O.; Sotnikov, A.; Suvurov, Y.; Tartaglia, R.; Tatarowicz, J.; Testera, G.; Tonazzo, A.; Unzhakov, E.; Vogelaar, R. B.; Wada, M.; Walker, S. E.; Wang, H.; Wang, Y.; Watson, A. W.; Westerdale, S.; Williams, R.; Wojcik, M.; Xu, J.; Yang, C. G.; Yoo, J.; Yu, B.; Zavatarelli, S.; Zhong, W. L.; Zuzel, G.

2015-01-01

Although the existence of dark matter is supported by many evidences, based on astrophysical measurements, its nature is still completely unknown. One major candidate is represented by weakly interacting massive particles (WIMPs), which could in principle be detected through their collisions with ordinary nuclei in a sensitive target, producing observable low-energy (<100 keV) nuclear recoils. The DarkSide program aims at the WIPMs detection using a liquid argon time projection chamber (LAr-TPC). In this paper we quickly review the DarkSide program focusing in particular on the next generation experiment DarkSide-G2, a 3.6-ton LAr-TPC. The different detector components are described as well as the improvements needed to scale the detector from DarkSide-50 (50 kg LAr-TPC) up to DarkSide-G2. Finally, the preliminary results on background suppression and expected sensitivity are presented

A Total Pleural Covering for Lymphangioleiomyomatosis Prevents Pneumothorax Recurrence

Science.gov (United States)

Kurihara, Masatoshi; Mizobuchi, Teruaki; Kataoka, Hideyuki; Sato, Teruhiko; Kumasaka, Toshio; Ebana, Hiroki; Yamanaka, Sumitaka; Endo, Reina; Miyahashira, Sumika; Shinya, Noriko; Seyama, Kuniaki

2016-01-01

Background Spontaneous pneumothorax is a major and frequently recurrent complication of lymphangioleiomyomatosis (LAM). Despite the customary use of pleurodesis to manage pnenumothorax, the recurrence rate remains high, and accompanying pleural adhesions cause serious bleeding during subsequent lung transplantation. Therefore, we have developed a technique of total pleural covering (TPC) for LAM to wrap the entire visceral pleura with sheets of oxidized regenerated cellulose (ORC) mesh, thereby reinforcing the affected visceral pleura and preventing recurrence. Methods Since January 2003, TPC has been applied during video-assisted thoracoscopic surgery for the treatment of LAM. The medical records of LAM patients who had TPC since that time and until August 2014 are reviewed. Results TPC was performed in 43 LAM patients (54 hemithoraces), 11 of whom required TPC bilaterally. Pneumothorax recurred in 14 hemithoraces (25.9%) from 11 patients (25.6%) after TPC. Kaplan-Meier estimates of recurrence-free hemithorax were 80.8% at 2.5 years, 71.7% at 5 years, 71.7% at 7.5 years, and 61.4% at 9 years. The recurrence-free probability was significantly better when 10 or more sheets of ORC mesh were utilized for TPC (P = 0.0018). TPC significantly reduced the frequency of pneumothorax: 0.544 ± 0.606 episode/month (mean ± SD) before TPC vs. 0.008 ± 0.019 after TPC (Ppneumothorax in LAM, was minimally invasive and rarely caused restrictive ventilatory impairment. PMID:27658250

Capacidade reprodutiva e preferência da traça-das-crucíferas para diferentes brassicáceas Reproductive capacity and preference of the diamondback moth feeding on different brassicacea

Directory of Open Access Journals (Sweden)

Sergio A De Bortoli

2011-06-01

oviposition of the diamondback moth. The experiments were carried out with the following cultivars: Midori and Chato-de-Quintal cabbage, hybrids of cabbage Top Seed® - Agristar (TPC 308, TPC 681 and TPC 668, cauliflower Bola de Neve, broccolis Ramoso Piracicaba Precoce and collard green Manteiga da Geórgia, being this last one used as the susceptible control. Through the biological parameters of P. xylostella we elaborated a fertility life table, Comparing the cultivars in relation to the pest reproductive capacity. Four leaf parts were placed in diamondback moth rearing chambers, being two leaves of the treatment and two of the control which, put together formed a circle with 8 cm in diameter. The parts were disposed in an equidistantly form, to perform the dual-choice test (feeding and oviposition preference and multiple-choice test, confronting all substrates (feeding preference. The cultivars that provided better development and reproduction for the diamondback moth were collard green Manteiga da Georgia and broccolis Ramoso Piracicaba Precoce. For feeding preference high susceptibility was verified in collard green Manteiga da Geórgia and TPC 681 and for oviposition preference high preference was observed for cauliflower Bola de Neve. Four different groups of cultivars could be formed: cabbage Midori as moderately resistant (MR; cauliflower Bola de Neve and cabbage Chato-de-Quintal as susceptible (S; broccolis, TPC 308, TPC 681 and TPC 668 as moderately susceptible (MS; and collard green as highly susceptible (HS.

The GAPS programme with HARPS-N at TNG. XVI. Measurement of the Rossiter-McLaughlin effect of transiting planetary systems HAT-P-3, HAT-P-12, HAT-P-22, WASP-39, and WASP-60

Science.gov (United States)

Mancini, L.; Esposito, M.; Covino, E.; Southworth, J.; Biazzo, K.; Bruni, I.; Ciceri, S.; Evans, D.; Lanza, A. F.; Poretti, E.; Sarkis, P.; Smith, A. M. S.; Brogi, M.; Affer, L.; Benatti, S.; Bignamini, A.; Boccato, C.; Bonomo, A. S.; Borsa, F.; Carleo, I.; Claudi, R.; Cosentino, R.; Damasso, M.; Desidera, S.; Giacobbe, P.; González-Álvarez, E.; Gratton, R.; Harutyunyan, A.; Leto, G.; Maggio, A.; Malavolta, L.; Maldonado, J.; Martinez-Fiorenzano, A.; Masiero, S.; Micela, G.; Molinari, E.; Nascimbeni, V.; Pagano, I.; Pedani, M.; Piotto, G.; Rainer, M.; Scandariato, G.; Smareglia, R.; Sozzetti, A.; Andreuzzi, G.; Henning, Th.

2018-05-01

Context. The measurement of the orbital obliquity of hot Jupiters with different physical characteristics can provide clues to the mechanisms of migration and orbital evolution of this particular class of giant exoplanets. Aims: We aim to derive the degree of alignment between planetary orbit and stellar spin angular momentum vectors and look for possible links with other orbital and fundamental physical parameters of the star-planet system. We focus on the characterisation of five transiting planetary systems (HAT-P-3, HAT-P-12, HAT-P-22, WASP-39, and WASP-60) and the determination of their sky-projected planet orbital obliquity through the measurement of the Rossiter-McLaughlin effect. Methods: We used HARPS-N high-precision radial velocity measurements, gathered during transit events, to measure the Rossiter-McLaughlin effect in the target systems and determine the sky-projected angle between the planetary orbital plane and stellar equator. The characterisation of stellar atmospheric parameters was performed by exploiting the HARPS-N spectra, using line equivalent width ratios and spectral synthesis methods. Photometric parameters of the five transiting exoplanets were re-analysed through 17 new light curves, obtained with an array of medium-class telescopes, and other light curves from the literature. Survey-time-series photometric data were analysed for determining the rotation periods of the five stars and their spin inclination. Results: From the analysis of the Rossiter-McLaughlin effect we derived a sky-projected obliquity of λ = 21.2° ± 8.7°, λ = -54°-13°+41°, λ = -2.1° ± 3.0°, λ = 0° ± 11°, and λ = -129° ± 17° for HAT-P-3 b, HAT-P-12 b, HAT-P-22 b, WASP-39 b, and WASP-60 b, respectively. The latter value indicates that WASP-60 b is moving on a retrograde orbit. These values represent the first measurements of λ for the five exoplanetary systems under study. The stellar activity of HAT-P-22 indicates a rotation period of 28.7 ± 0

Analysis of GEM properties and development of a GEM support structure for the ILD time projection chamber

International Nuclear Information System (INIS)

Hallermann, Lea

2010-04-01

In the concept of the International Large Detector (ILD), developed for the International Linear Collider (ILC) a Time Projection Chamber (TPC) is envisaged as main tracking detector. Such gaseous detectors have to be equipped with amplification devices in order to enlarge the amount of charge, which is set free by ionization caused by traversing charged particles. Micro Pattern Gas Detectors (MPGDs) will be used in the ILD TPC as amplification stage. In this thesis, Gas Electron Multipliers (GEMs) - one specific MPGD species - are analyzed concerning various properties. Effective gains and energy resolutions are compared for GEM foils produced by different manufacturers. A good understanding of these observables is obtained by interpretation of the results with the help of geometrical parameters. Height profile measurements of GEM foils have been performed for the first time and the impact of non perfect flat GEMs is analyzed, especially on dE/dx determination and drift field quality. The results emphasize the need of a flat installation of GEMs in TPCs. As a consequence, a new mounting device has been developed to ensure flatness and to provide a method to cover large readout areas, as in the ILD TPC, by introducing the least possible amount of dead material into the detector. The developed structure has been tested in a TPC protoype, taking cosmic muon data. The influence of the mounting on track reconstruction, single point resolution, tracking efficiency and dE/dx measurements is quantified. The developed mounting is applicable in a large scale TPC, if some design considerations are taken into account. (orig.)

Analysis of GEM properties and development of a GEM support structure for the ILD time projection chamber

Energy Technology Data Exchange (ETDEWEB)

Hallermann, Lea

2010-04-15

In the concept of the International Large Detector (ILD), developed for the International Linear Collider (ILC) a Time Projection Chamber (TPC) is envisaged as main tracking detector. Such gaseous detectors have to be equipped with amplification devices in order to enlarge the amount of charge, which is set free by ionization caused by traversing charged particles. Micro Pattern Gas Detectors (MPGDs) will be used in the ILD TPC as amplification stage. In this thesis, Gas Electron Multipliers (GEMs) - one specific MPGD species - are analyzed concerning various properties. Effective gains and energy resolutions are compared for GEM foils produced by different manufacturers. A good understanding of these observables is obtained by interpretation of the results with the help of geometrical parameters. Height profile measurements of GEM foils have been performed for the first time and the impact of non perfect flat GEMs is analyzed, especially on dE/dx determination and drift field quality. The results emphasize the need of a flat installation of GEMs in TPCs. As a consequence, a new mounting device has been developed to ensure flatness and to provide a method to cover large readout areas, as in the ILD TPC, by introducing the least possible amount of dead material into the detector. The developed structure has been tested in a TPC protoype, taking cosmic muon data. The influence of the mounting on track reconstruction, single point resolution, tracking efficiency and dE/dx measurements is quantified. The developed mounting is applicable in a large scale TPC, if some design considerations are taken into account. (orig.)

Expressing emotions in blogs

DEFF Research Database (Denmark)

Rodriguez-Hidalgo, Carmina Rodriguez-Hidalgo; Tan, Ed S.; Verlegh, Peeter

2017-01-01

Textual paralanguage cues (TPC) have been signaled as effective emotion transmitters online. Though several studies have investigated their properties and occurrence, there remains a gap concerning their communicative impact within specific psychological processes, such as the social sharing...... of emotion (SSE, Rimé, 2009). This study content-analyzed Live Journal blogposts for the occurrence of TPC in three phases of online SSE: initiation, feedback and repost. We compared these to TPC on a second type of emotional expression, emotional venting. Based on Social Information processing theory (SIP......, Walther, 1992), and on the Emotional Mimicry in Context (EMC, Hess & Fischer, 2013) framework, we study predictive relationships in TPC usage in our phased model of online SSE. Results showed that TPC prevailed in SSE blogposts and strongly dominated in emotional venting posts. TPC was more common...

Antioxidant and DNA damage protective properties of anthocyanin-rich extracts from Hibiscus and Ocimum: a comparative study.

Science.gov (United States)

Sarkar, Biswatrish; Kumar, Dhananjay; Sasmal, Dinakar; Mukhopadhyay, Kunal

2014-01-01

Anthocyanin extracts (AEs) from Ocimum tenuiflorum (leaf), Hibiscus rosa-sinensis (petal) and Hibiscus sabdariffa (calyx) were investigated and compared for in vitro antioxidant activity and DNA damage protective property. Total phenolic content (TPC) and total anthocyanin content (TAC) of the AEs were determined and the major anthocyanins were characterised. In vitro antioxidant activities were assessed by ferric-reducing antioxidant power (FRAP) assay, 2,2-diphenyl-1-picryl hydrazyl (DPPH) radical-scavenging activity, 2-deoxy-D-ribose degradation assay and lipid peroxidation assay. The protective property of the AEs was also examined against oxidative DNA damage by H2O2 and UV using pUC19 plasmid. All the AEs particularly those from O. tenuiflorum demonstrated efficient antioxidant activity and protected DNA from damage. Strong correlation between antioxidant capacity and TPC and TAC was observed. Significant correlation between antioxidant capacity and TPC and TAC ascertained that phenolics and anthocyanins were the major contributors of antioxidant activity.

Influence of variety and harvest maturity on phytochemical content in corn silk.

Science.gov (United States)

Sarepoua, Eakrin; Tangwongchai, Ratchada; Suriharn, Bhalang; Lertrat, Kamol

2015-02-15

Corn silk has been used as a traditional herb in Asia. The objective of this study was to evaluate variability in phytochemicals in corn varieties at three maturity stages of corn silk. Ten vegetable corn varieties were evaluated in a completely randomized design with three replications. Data were recorded for total phenolic (TPC), total flavonoids (TFC), total anthocyanin (TAC) and antioxidant activity (AA) by DPPH free-radical-scavenging assays. Differences among corn varieties were observed for all parameters at all maturity stages, and the interactions between maturity stage and corn variety were significant. TPC and TAC were highest at the milky stage, whereas TFC and AA were highest at the silking stage. TPC, TFC and AA were highest in super sweet corn and white corn at the silking stage. PWC5 variety of purple waxy corn at the milky stage had the highest values for all parameters, and it is useful for further development of functional food products. Copyright © 2014 Elsevier Ltd. All rights reserved.

Drying effects on the antioxidant properties of tomatoes and ginger.

Science.gov (United States)

Gümüşay, Özlem Aktürk; Borazan, Alev Akpınar; Ercal, Nuran; Demirkol, Omca

2015-04-15

In this study, the effects of four different drying processes, sun drying (SD), oven drying (OD), vacuum oven drying (VOD) and freeze drying (FD) for tomatoes (Solanum lycopersicum) and ginger (Zingiber officinale) in terms of thiolic and phenolic contents have been studied. Thiol content, total phenolic content (TPC), ascorbic acid (AA) content, and cupric ion reducing antioxidant capacity (CUPRAC) were determined in fresh and dried samples. Glutathione (GSH) and cysteine (Cys) were determined as the thiol contents of tomatoes and ginger. Significant losses were observed in the contents of TPC, AA, GSH and Cys and CUPRAC values in all samples that were dried using the thermal method. There was a statistically significant difference in the losses of the TPC, AA, and thiol contents between the use of thermal drying and freeze drying (except Cys in tomatoes) methods. Freeze dried tomato and ginger samples have been found to have better antioxidant properties. Copyright © 2014 Elsevier Ltd. All rights reserved.

Intra-molecular Charge Transfer and Electron Delocalization in Non-fullerene Organic Solar Cells

Energy Technology Data Exchange (ETDEWEB)

Wu, Qinghe [Department of Chemistry, Key Laboratory for Preparation and Application of Ordered Structural Materials of Guangdong Province, Shantou University, Guangdong 515063, P. R. China; Zhao, Donglin [Department of Chemistry, The James Franck Institute, The University of Chicago, 929 E 57th Street, Chicago, Illinois 60637, United States; Goldey, Matthew B. [Institute for Molecular Engineering, The University of Chicago, 5747 South Ellis Avenue, Chicago, Illinois 60637, United States; Filatov, Alexander S. [Department of Chemistry, The James Franck Institute, The University of Chicago, 929 E 57th Street, Chicago, Illinois 60637, United States; Sharapov, Valerii [Department of Chemistry, The James Franck Institute, The University of Chicago, 929 E 57th Street, Chicago, Illinois 60637, United States; Colón, Yamil J. [Institute for Molecular Engineering, Materials Science Division, Argonne National Laboratory, 9700 Cass Avenue, Lemont, Illinois 60439, United States; Institute for Molecular Engineering, The University of Chicago, 5747 South Ellis Avenue, Chicago, Illinois 60637, United States; Cai, Zhengxu [Department of Chemistry, The James Franck Institute, The University of Chicago, 929 E 57th Street, Chicago, Illinois 60637, United States; Chen, Wei [Institute for Molecular Engineering, Materials Science Division, Argonne National Laboratory, 9700 Cass Avenue, Lemont, Illinois 60439, United States; Institute for Molecular Engineering, The University of Chicago, 5747 South Ellis Avenue, Chicago, Illinois 60637, United States; de Pablo, Juan [Institute for Molecular Engineering, Materials Science Division, Argonne National Laboratory, 9700 Cass Avenue, Lemont, Illinois 60439, United States; Institute for Molecular Engineering, The University of Chicago, 5747 South Ellis Avenue, Chicago, Illinois 60637, United States; Galli, Giulia [Institute for Molecular Engineering, Materials Science Division, Argonne National Laboratory, 9700 Cass Avenue, Lemont, Illinois 60439, United States; Institute for Molecular Engineering, The University of Chicago, 5747 South Ellis Avenue, Chicago, Illinois 60637, United States; Yu, Luping [Department of Chemistry, The James Franck Institute, The University of Chicago, 929 E 57th Street, Chicago, Illinois 60637, United States

2018-03-02

Two types of electron acceptors were synthesized by coupling two kinds of electron-rich cores with four equivalent perylene diimides (PDIs) at the a position. With fully aromatic cores, TPB and TPSe have pi-orbitals spread continuously over the whole aromatic conjugated backbone, unlike TPC and TPSi, which contain isolated PDI units due to the use of a tetrahedron carbon or silicon linker. Density functional theory calculations of the projected density of states showed that the highest occupied molecular orbital (HOMO) and lowest unoccupied molecular orbital (LUMO) for TPB are localized in separate regions of space. Further, the LUMO of TPB shows a greater contribution from the orbitals belonging to the connective core of the molecules than that of TPC. Overall, the properties of the HOMO and LUMO point at increased intra-molecular delocalization of negative charge carriers for TPB and TPSe than for TPC and TPSi and hence at a more facile intra-molecular charge transfer for the former. The film absorption and emission spectra showed evidences for the inter -molecular electron delocalization in TPB and TPSe, which is consistent with the network structure revealed by X-ray diffraction studies on single crystals of TPB. These features benefit the formation of charge transfer states and/or facilitate charge transport. Thus, higher electron mobility and higher charge dissociation probabilities under J(sc) condition were observed in blend films of TPB:PTB7-Th and TPSe:PTB7-Th than those in TPC:PTB7Th and TPSi:PTB7-Th blend films. As a result, the J(sc) and fill factor values of 15.02 mA/cm(2), 0.58 and 14.36 mA/cm(2), 0.55 for TPB- and TPSe-based solar cell are observed, whereas those for TPC and TPSi are 11.55 mA/cm2, 0.47 and 10.35 mA/cm(2), 0.42, respectively.

Musical instruments depicted in medieval Serbian art under oriental and western influences

Directory of Open Access Journals (Sweden)

Pejović Roksanda

2005-01-01

Full Text Available Researching musical instruments on frescoes, miniatures, icons and sculptural decorations of mediaeval Serbian art, painted and sculptured in the manner of Byzantine art, we discover Oriental and Western influences. Musical instruments arriving from the Orient were unchanged for centuries and those from West Europe were mainly used in the Middle Ages or the Renaissance. Oriental and Western influences can be observed on instruments of all families-idiophones, membranophones, bowed and string instruments, as well as on aero phones. The same form of some crotales and cymbals can be found both in Oriental and Western art, the majority of membranophones are of Oriental origin, but the tambourine on Bodani frescoes originated in West Europe. Lyres and angular harps are close to Antique tradition. Some bowed instruments, psalteries, lutes, harps, short horns, business and shawms have Oriental patterns and other instruments of these families accepted Western shapes. There are, as well, same kinds of bowed instruments and S-trumpets peculiar for both continents.

Assessment of proactive transmission power control for wireless sensor networks

NARCIS (Netherlands)

kotian, Roshan; Exarchakos, Georgios; Liotta, Antonio

2014-01-01

In order to prolong lifetime of Wireless Sensor Networks (WSN), Transmission Power Control (TPC) techniques are employed. The existing TPC schemes adjust the transmission power mostly reacting to changes at link quality between communicating nodes. Proactive TPC has been proposed in the recent past

Characterization of bioactive compounds of Annona cherimola L. leaves using a combined approach based on HPLC-ESI-TOF-MS and NMR.

Science.gov (United States)

Díaz-de-Cerio, Elixabet; Aguilera-Saez, Luis Manuel; Gómez-Caravaca, Ana María; Verardo, Vito; Fernández-Gutiérrez, Alberto; Fernández, Ignacio; Arráez-Román, David

2018-06-01

Annona cherimola Mill. (cherimoya) has widely been used as food crop. The leaves of this tree possess several health benefits, which are, in general, attributed mainly to its bioactive composition. However, literature concerning a comprehensive characterization based on a combined approach, which consists of nuclear magnetic resonance (NMR) and high-performance liquid chromatography coupled with time-of-flight mass spectrometry (HPLC-TOF-MS), from these leaves is scarce. Thus, the aim of this work was to study the polar profile of full extracts of cherimoya leaves by using these tools. Thus, a total of 77 compounds have been characterized, 12 of which were identified by both techniques. Briefly, 23 compounds were classified as amino acids, organic acids, carbohydrates, cholines, phenolic acid derivatives, and flavonoids by NMR, while 66 metabolites were divided into sugars, amino acids, phenolic acids and derivatives, flavonoids, phenylpropanoids, and other polar compounds by HPLC-TOF-MS. It is worth mentioning that different solvent mixtures were tested and the total phenolic content in the extracts quantified (TPC via HPLC-TOF-MS). The tendency observed was EtOH/water 80/20 (v/v) (17.0 ± 0.2 mg TPC/g leaf dry weight (d.w.)) ≥ acetone/water 70/30 (v/v) (16.1 ± 0.7 mg TPC/g leaf d.w.) > EtOH/water 70/30 (v/v) (14.0 ± 0.3 mg TPC/g leaf d.w.) > acetone/water 80/20 (v/v) (13.5 ± 0.4 mg TPC/g leaf d.w.). Importantly, flavonoids derivatives were between 63 and 76% of the TPC in those extracts. Major compounds were sucrose, glucose (α and β), and proline, and chlorogenic acid and rutin for NMR and HPLC-TOF-MS, respectively. Graphical abstract The combined use of LC-HRMS and NMR is a potential synergic combination for a comprehensive metabolite composition of cherimoya leaves.

Gait-Cycle-Driven Transmission Power Control Scheme for a Wireless Body Area Network.

Science.gov (United States)

Zang, Weilin; Li, Ye

2018-05-01

In a wireless body area network (WBAN), walking movements can result in rapid channel fluctuations, which severely degrade the performance of transmission power control (TPC) schemes. On the other hand, these channel fluctuations are often periodic and are time-synchronized with the user's gait cycle, since they are all driven from the walking movements. In this paper, we propose a novel gait-cycle-driven transmission power control (G-TPC) for a WBAN. The proposed G-TPC scheme reinforces the existing TPC scheme by exploiting the periodic channel fluctuation in the walking scenario. In the proposed scheme, the user's gait cycle information acquired by an accelerometer is used as beacons for arranging the transmissions at the time points with the ideal channel state. The specific transmission power is then determined by using received signal strength indication (RSSI). An experiment was conducted to evaluate the energy efficiency and reliability of the proposed G-TPC based on a CC2420 platform. The results reveal that compared to the original RSSI/link-quality-indication-based TPC, G-TPC reduces energy consumption by 25% on the sensor node and reduce the packet loss rate by 65%.

Triptycene-Based Microporous Cyanate Resins for Adsorption/Separations of Benzene/Cyclohexane and Carbon Dioxide Gas.

Science.gov (United States)

Deng, Gaoyang; Wang, Zhonggang

2017-11-29

Triptycene-based cyanate monomers 2,6,14-tricyanatotriptycene (TPC) and 2,6,14-tris(4-cyanatophenyl)triptycene (TPPC) that contain different numbers of benzene rings per molecule were synthesized, from which two microporous cyanate resins PCN-TPC and PCN-TPPC were prepared. Of interest is the observation that the two polymers have very similar porosity parameters, but PCN-TPPC uptakes considerably higher benzene (77.8 wt %) than PCN-TPC (17.6 wt %) at room temperature since the higher concentration of phenyl groups in PCN-TPPC enhances the π-π interaction with benzene molecules. Besides, the adsorption capacity of benzene in PCN-TPPC is dramatically 7 times as high as that of cyclohexane. Contrary to the adsorption of organic vapors, at 273 K and 1.0 bar, PCN-TPC with more heteroatoms in the network skeleton displays larger uptake of CO 2 and higher CO 2 /N 2 selectivity (16.4 wt %, 60) than those of PCN-TPPC (14.0 wt %, 39). The excellent and unique adsorption properties exhibit potential applications in the purification of small molecular organic hydrocarbons, e.g., separation of benzene from benzene/cyclohexane mixture as well as CO 2 capture from flue gas. Moreover, the results are helpful for deeply understanding the effect of porous and chemical structures on the adsorption properties of organic hydrocarbons and CO 2 gas.

Status report of PEP-4

International Nuclear Information System (INIS)

Kamae, Tuneyoshi

1982-01-01

The present status of PEP-4 is reported. The cosmic ray test of a TPC without magnetic field was done in July, 1981, and tracks were observed on the first day of the test. The entire PEP-4 detector was tested with 3.9 kG magnetic field in November, 1981, and various trigger configurations were tested. The TPC performed well during the test, and a preliminary analysis gave an encouraging position resolution which is expected to be improved with the correction for various non-uniformity and by refining the fitting procedure. Furthermore, the detection efficiency of the muon chamber was about 99 %. In November and December, 1981, the cosmic ray test of the hexagonal calorimeter was carried out. The performance was just as expected. Noise did not pose any problem, and the peak of the Fourier coefficient gave a nice overall calibration of the calorimeter. There are some problems to be solved in future. With the TPC, the impurities in the gas, the electronic noise, the hooks and the magnetic coil should be improved. In addition, there are some problems with the inner drift chamber, the hexagonal calorimeter and the relativistic rise measured by the TPC. The very recent results with the first e + e - beam obtained in February, 1982, are briefly reported, although the events have not been fully analyzed. (Ito, K.)

Real time data acquisition for a time projection chamber using a high speed DEC-RT11 to UNIX UDP-TCP/IP interface

International Nuclear Information System (INIS)

Thomas, J.; Douglas, M.; Watanabe, R.; Henrikson, H.E.; Iqbal, M.Z.; Mitchell, L.W.; O'Callaghan, B.M.G.; Wong, H.T.K.; Melvin, J.D.

1987-01-01

The authors built a high pressure xenon Time Projection Chamber to study double beta decay, a process of fundamental interest which, if observed, would indicate that the neutrino is a massive Majorana particle. Raw data rates from the TPC exceed 200 Kbytes per second. The TPC is operated through a CAMAC interface with a DEC LSI-11/73 computer networked to a Tektronix 6130 workstation. Data is transmitted at about 15 Kbytes per second although the network is capable of transmitting data at 80 Kbytes per second. The only system level programming required was to write a UDP-TCP/IP driver for the DEC-DEQNA Ethenet board on the 11/73

Increased synthesis of heparin affin regulatory peptide in the perforant path lesioned mouse hippocampal formation

DEFF Research Database (Denmark)

Poulsen, F R; Lagord, C; Courty, J

2000-01-01

Heparin affin regulatory peptide (HARP), also known as pleiotrophin or heparin-binding growth-associated molecule, is a developmentally regulated extracellular matrix protein that induces cell proliferation and promotes neurite outgrowth in vitro as well as pre- and postsynaptic developmental...... differentiation in vivo. Here we have investigated the expression of HARP mRNA and protein in the perforant path lesioned C57B1/6 mouse hippocampal formation from 1 to 35 days after surgery. This type of lesion induces a dense anterograde and terminal axonal degeneration, activation of glial cells, and reactive...... axonal sprouting within the perforant path zones of the fascia dentata and hippocampus as well as axotomy-induced retrograde neuronal degeneration in the entorhinal cortex. Analysis of sham- and unoperated control mice showed that HARP mRNA is expressed in neurons and white and gray matter glial cells...

Application of fourier-transform infrared (ft-ir) spectroscopy for determination of total phenolics of freeze dried lemon juices

International Nuclear Information System (INIS)

Sherazi, S.T.H.; Bhutto, A.A.; Mehesar, S.A.

2017-01-01

A cost effective and environmentally safe analytical method for rapid assessment of total phenolic content (TPC) in freeze dried lemon juice samples was developed using transmission Fourier-transform infrared spectroscopy (FT-IR) in conjunction with chemometric techniques. Two types of calibrations i.e. simple Beer's law and partial least square (PLS) were applied to investigate most accurate calibration model based on region from1420 to 1330 cm-1. The better analytical performance was obtained by PLS technique coefficient of determination (R2), root mean square error of calibration (RMSEC) with the value of 0.999 and 0.00864, respectively. The results of TPC in freeze dried lemon juice samples obtained by transmission FT-IR were compared with TPC observed by Folin-Ciocalteu (FC) assay and found to be comparable. Outcomes of the present study indicate that transmission FT-IR spectroscopic approach could be used as an alternative approach in place of Folin-Ciocalteu (FC) assay which is expensive and time-consuming conventional chemical methods for determination of the total phenolic content of lemon fruits. (author)

[Quality evaluation and antioxidant activity research of Schisandra chinensis from various habitats].

Science.gov (United States)

Han, Zhi-Fu; Hu, Gao-Sheng; Li, Na; Fan, Xing; Jia, Jing-Ming

2012-12-01

To determine the contents of lignans, crude polysaccharides (CP) and total phenolic compounds (TPC) of Schisandra chinensis from various habitats in Liaoning province and evaluate their quality and free radical scavenging (FRS) activity. Contents of schisandrol, deoxyschizandrin and schisandrin B were determined by RP-HPLC. Contents of TPC, CP and FRS activity were determined by Folin-Cicalteu's, phenol-sulfuric acid and DPPH x method, respectively. Sample from Liaoyang city had the highest contents of lignans (21.75 mg/g); Sample from Shenbei New district of Shenyang city had the highest contents of CP (88.72 mg/g); Sample from Guanmenshan district of Benxi city had the highest contents of TPC and FRS activity (26.06 mg/g and 86.3%, respectively). Linear regression analysis results showed that contents of TPC had higher correlation coefficient with FRS activity than that of lignans. Their linear regression equations were Y = 1.3677X + 46.97, R2 = 0.6869 and Y = 2.5916X + 57.927, R2 = 0.1747 for TPC and lignans with FRS activity, respectively. The contents of lignans, CP and TPC are significantly different from samples collected from various habitats in Liaoning province. The main antioxidative substances are TPC, and lignans have no significant correlation with FRS activity.

Trabalho de casa, auto-eficácia e rendimento em matemática

Directory of Open Access Journals (Sweden)

Pedro Sales Luís Rosário

Full Text Available O Trabalho de Casa (TPC é uma estratégia instrutiva amplamente utilizada na Escola de muitos países. O TPC é um processo complexo que é afectado por múltiplos factores de ordem cognitiva, motivacional, social e contextual. A investigação tem-se centrado no tempo despendido na realização das tarefas de TPC, no entanto os resultados de vários estudos e as críticas metodológicas sugerem a necessidade de direccionar a pesquisa para outras variáveis. O objectivo deste estudo é a análise do poder preditivo da auto-eficácia percebida na Matemática e de três dimensões menos exploradas na literatura do TPC (e.g., número de TPC prescritos, taxa de completamento, e correcção percebida do TPC sobre o rendimento a matemática, em alunos portugueses do 5.º e 6.º ano de escolaridade (10 e 11 anos. Os resultados sugerem que o rendimento a matemática se encontra explicado, positiva e significativamente, pelas variáveis escolhidas. As conclusões sugerem a urgência de repensar o TPC como ferramenta educativa promotora do sucesso académico.

Determination of the equation of state of asymmetric nuclear matter

Energy Technology Data Exchange (ETDEWEB)

Tsang, Manyee Betty [Michigan State Univ., East Lansing, MI (United States)

2016-12-30

A new Time Projection Chamber (TPC), called the SπRIT (SAMURAI pion Reconstruction Ion Tracker) TPC was constructed and used successfully in two experiments with the SAMURAI spectrometer at RIKEN, Japan to study the equation of state of neutron rich matter. As a result of the project, the SπRIT collaboration, an international collaboration consisting of groups from US, Japan, Korea, Poland, China and Germany, has been formed to pursue the science opportunities provided by the SπRIT TPC. After completion of the TPC and the two experiments, the collaboration continues to develop the software to analyze the SπRIT experiments and extract constraints of symmetry energy at supra-saturation densities. Over 250 TB of data have been obtained in the last SπRIT TPC experimental campaign. Construction of the TPC provided opportunities for the scientists to develop new designs for the light-weight and thin-walled field cage for the large pad plane and for the gating grid. Two PhD students (1 US and 1 Korea) graduated in 2016 based on their research on the TPC. At least four more doctoral theses (2 US, 1 Japan and 1 Korea) based on physics from the SπRIT experiments are expected.

Relationship between total polar components and polycyclic aromatic hydrocarbons in fried edible oil.

Science.gov (United States)

An, Ke-Jing; Liu, Yu-Lan; Liu, Hai-Lan

2017-09-01

Deep-fried dough sticks (a Chinese traditional breakfast) were fried individually in peanut, sunflower, rapeseed, rice bran, soybean and palm oil without any time lag for 32 h (64 batches fried, each for 30 min) and fried oil samples were obtained every 2 h. The frying-induced changes in the levels of total polar compounds (TPC) and polycyclic aromatic hydrocarbons (PAHs) were investigated by edible oil polar compounds (EOPC) fast separation chromatographic system and gas chromatography-mass spectrometry (GC-MS), respectively. The correlations were analysed of TPC with benzo[a]pyrene (BaP), TPC and PAH4 (benzo[a]anthracene, chrysene, benzo[b]fluoranthene and benzo[a]pyrene) as well as TPC with PAH16 (USEPA 16 PAHs). The results revealed that the levels of TPC and PAHs in fried oil considerably increased with frying time, and the type of oil affected their formation, which could inform the choice of oil for frying. The total BaP equivalents (∑BaPeq) concentrations in fresh oil and in oil whose TPC exceeded 27% were 2.14-13.48 and 5.78-10.80 μg kg -1 , respectively, which means that the carcinogenic potency of frying oil was more pronounced than that of fresh oil. In addition, the TPC concentration was significantly correlated with the concentrations of the sum of the 16 PAHs, PAH4 and BaP, so that the levels of PAHs could be predicted according to the levels of TPC in fried oil. In European standards, the rejection point for TPC in frying oil should be recalculated when considered PAHs. In all, the concentration of PAHs is a vital factor for ensuring the safety of frying oil.

Occupancy in the CLIC ILD Time Projection Chamber using Pixelised Readout

CERN Document Server

Killenberg, Martin

2013-01-01

The occupancy in the CLIC ILD TPC caused by the beam induced background from gamma gamma -> hadrons, e+e- pairs and beam halo muons is very high for conventional pad readout. We show that the occupancy for a pixelised TPC readout is moderate and might be a viable solution to operate a TPC at CLIC.

New readout and data-acquisition system in an electron-tracking Compton camera for MeV gamma-ray astronomy (SMILE-II)

Energy Technology Data Exchange (ETDEWEB)

Mizumoto, T., E-mail: mizumoto@cr.scphys.kyoto-u.ac.jp [Department of Physics, Kyoto University, 606-8502 Kyoto (Japan); Matsuoka, Y. [Department of Physics, Kyoto University, 606-8502 Kyoto (Japan); Mizumura, Y. [Unit of Synergetic Studies for Space, Kyoto University, 606-8502 Kyoto (Japan); Department of Physics, Kyoto University, 606-8502 Kyoto (Japan); Tanimori, T. [Department of Physics, Kyoto University, 606-8502 Kyoto (Japan); Unit of Synergetic Studies for Space, Kyoto University, 606-8502 Kyoto (Japan); Kubo, H.; Takada, A.; Iwaki, S.; Sawano, T.; Nakamura, K.; Komura, S.; Nakamura, S.; Kishimoto, T.; Oda, M.; Miyamoto, S.; Takemura, T.; Parker, J.D.; Tomono, D.; Sonoda, S. [Department of Physics, Kyoto University, 606-8502 Kyoto (Japan); Miuchi, K. [Department of Physics, Kobe University, 658-8501 Kobe (Japan); Kurosawa, S. [Institute for Materials Research, Tohoku University, 980-8577 Sendai (Japan)

2015-11-11

For MeV gamma-ray astronomy, we have developed an electron-tracking Compton camera (ETCC) as a MeV gamma-ray telescope capable of rejecting the radiation background and attaining the high sensitivity of near 1 mCrab in space. Our ETCC comprises a gaseous time-projection chamber (TPC) with a micro pattern gas detector for tracking recoil electrons and a position-sensitive scintillation camera for detecting scattered gamma rays. After the success of a first balloon experiment in 2006 with a small ETCC (using a 10×10×15 cm{sup 3} TPC) for measuring diffuse cosmic and atmospheric sub-MeV gamma rays (Sub-MeV gamma-ray Imaging Loaded-on-balloon Experiment I; SMILE-I), a (30 cm){sup 3} medium-sized ETCC was developed to measure MeV gamma-ray spectra from celestial sources, such as the Crab Nebula, with single-day balloon flights (SMILE-II). To achieve this goal, a 100-times-larger detection area compared with that of SMILE-I is required without changing the weight or power consumption of the detector system. In addition, the event rate is also expected to dramatically increase during observation. Here, we describe both the concept and the performance of the new data-acquisition system with this (30 cm){sup 3} ETCC to manage 100 times more data while satisfying the severe restrictions regarding the weight and power consumption imposed by a balloon-borne observation. In particular, to improve the detection efficiency of the fine tracks in the TPC from ~10% to ~100%, we introduce a new data-handling algorithm in the TPC. Therefore, for efficient management of such large amounts of data, we developed a data-acquisition system with parallel data flow.

The Educational Concepts of F.-C. La Hapre and Their Forming: European Ideals and Russian Realization

Directory of Open Access Journals (Sweden)

Andreev Andrei

2016-08-01

Full Text Available As an actual problem in the modern historical studies is discussed how the educational ideals in the Russian culture were formed and developed. The subject of this article reveals the same problem from the biography of the Swiss pedagogue, who was commended to teach the grandsons of the Russian empress Catherine II, Frédéric-César de La Harpe. Inspite of the high reputation of the Swiss tutors at the end of 18th century, La Harpe wasn’t a pedagogue by profession — it was rather by chance that his career in Russia went that way. But at the same time La Harpe made great efforts after his appointment to the Russian court in order to become familiar with the main pedagogical literature of his time, and therefore he could “make himself his own position” among other tutors, becoming de facto the main teacher of Alexander I, and had a great influence on the personality of the future Russian emperor. The pedagogical concepts of La Harpe were closely connected with those of Catherine II, formulated in her “Instruction” for her grandson’s teachers and aimed at the formation of a new enlightened monarch for Russia. The “educational standard” by La Harpe included all principals ciences of the Age of Enlightenment, with the stress on history and philosophy, as well as “civil education”, which was meant to help the future ruler to make a “clear concept of his duties”. But here a lization of these ideas was opposed by the court milieu and lead to the number of conflicts, which caused the generally uncompleted character of the education of Alexander I.

Antioxidant activity of commonly consumed cereals, millets, pulses and legumes in India.

Science.gov (United States)

Sreeramulu, D; Reddy, C Vijaya Kumar; Raghunath, M

2009-02-01

Plant foods are important due to their antioxidant activity (AOA) attributed to the phenolics which are known to protect organisms against harmful effects of oxygen radicals. However, information on antioxidant activity of Indian plant foods is scanty. Therefore, the present study evaluated the AOA of cereals, millets, pulses and legumes, commonly consumed in India and assessed the relationship with their total phenolic content (TPC). AOA was assessed by DPPH (2,2-Diphenyl-1-picryl hydrazyl) radical scavenging assay, ferric reducing antioxidant power (FRAP) assay and reducing power. DPPH scavenging activity ranged from 0.24 and 1.73 mg/g, whereas FRAP ranged from 16.21 to 471.71 micromoles/g. Finger millet (Eleusine cora cana) and Rajmah (Phaseolus vulgaris) had the highest FRAP 471.71, 372.76 and DPPH scavenging activity 1.73, 1.07. Similar trends were observed with reducing power. Among cereals and legumes, Finger millet (Ragi) and black gram dhal (Phaseolus mungo Roxb) had the highest TPC, the values being 373 and 418 mg/100 g respectively, while rice (Oryza sativa) and green gram dhal (Phaseolus aureus Roxb) showed the least (47.6 and 62.4 mg/100 g). In the present study, FRAP (r = 0.91) and reducing power (r = 0.90) showed significant correlation with TPC in cereals and millets, but not in pulses and legumes. The results suggest that TPC contributes significantly to the AOA of Indian cereals and millets.

Antioxidant Activity of the Lignins Derived from Fluidized-Bed Fast Pyrolysis

Directory of Open Access Journals (Sweden)

Sohail S. Qazi

2017-03-01

Full Text Available A challenge in recent years has been the rational use of forest and agriculture residues for the production of bio-fuel, biochemical, and other bioproducts. In this study, potentially useful compounds from pyrolytic lignins were identified by HPLC-MS/MS and untargeted metabolomics. The metabolites identified were 2-(4-allyl-2-methoxyphenoxy-1-(4-hydroxy-3-methoxyphenyl-1-propanol, benzyl benzoate, fisetinidol, phenyllactic acid, 2-phenylpropionic acid, 6,3′-dimethoxyflavone, and vanillin. The 2,2-diphenyl-1-picrylhydrazyl radical scavenging activity (DPPH, trolox equivalent antioxidant capacity (TEAC, and total phenolics content (TPC per gram of pyrolytic lignin ranged from 14 to 503 mg ascorbic acid equivalents, 35 to 277 mg trolox equivalents, and 0.42 to 50 mg gallic acid equivalents, respectively. A very significant correlation was observed between the DPPH and TPC (r = 0.8663, p ≤ 0.0001, TEAC and TPC (r = 0.8044, p ≤ 0.0001, and DPPH and TEAC (r = 0.8851, p ≤ 0.0001. The polyphenolic compounds in the pyrolytic lignins which are responsible for radical scavenging activity and antioxidant properties can be readily profiled with HPLC-MS/MS combined with untargeted metabolomics. The results also suggest that DPPH, TEAC, and TPC assays are suitable methods for the measurement of antioxidant activity in a variety of pyrolytic lignins. These data show that the pyrolytic lignins can be considered as promising sources of natural antioxidants and value-added chemicals.

The influence of ripening stage and cultivation system on the total antioxidant activity and total phenolic compounds of yellow passion fruit pulp.

Science.gov (United States)

Macoris, Mariana S; De Marchi, Renata; Janzantti, Natália S; Monteiro, Magali

2012-07-01

This work aimed to investigate the influence of both ripening stage and cultivation system on the total phenolic compounds (TPC) and total antioxidant activity (TAA) of passion fruit pulp. TPC extraction was optimized using a 2³ central composed design. The variables were fruit pulp volume, methanol volume and extraction solution volume. TPC was determined using the Folin-Ciocalteu reaction, and TAA using the ABTS radical reaction. The conditions to extract TPC were 2 mL passion fruit pulp and 9 mL extraction solution containing 40% methanol:water (v/v). TPC values increased in the passion fruit pulp during ripening for both cultivation systems, ranging from 281.8 to 361.9 mg gallic acid L⁻¹ (P ≤ 0.05) for the organic pulp and from 291.0 to 338.6 mg gallic acid L⁻¹ (P ≤ 0.05) for the conventional pulp. TPC values increased during ripening for both organic and conventional passion fruit. The same was true for TAA values for conventional passion fruit. For organic passion fruit, however, TAA values were highest at the initial ripening stages. These results suggest that antioxidant compounds exert strong influence on the initial ripening stages for organic passion fruit, when TPC still did not reach its maximum level. Copyright © 2012 Society of Chemical Industry.

Fabrication of Mesoporous Silica/Alumina Hybrid Membrane Film Nanocomposites using Template Sol-Gel Synthesis of Amphiphilic Triphenylene

Science.gov (United States)

Lintang, H. O.; Jalani, M. A.; Yuliati, L.; Salleh, M. M.

2017-05-01

Herein we reported that by introducing a one-dimensional (1D) substrate with a porous structure such as anodic aluminum oxide (AAO) membrane, mesoporous silica/alumina hybrid nanocomposites were successfully fabricated by using amphiphilic triphenylene (TPC10TEG) as a template in sol-gel synthesis (TPC10TEG/silicahex). For the optical study of the nanocomposites, TPC10TEG/silicahex showed absorption peak at 264 nm due to the ordered and long-range π-π stacking of the disc-like aromatic triphenylene core. Moreover, the hexagonal arrangement of TPC10TEG/silicahex was proven based on their diffraction peaks of d 100 and d 200 at 2θ = 2.52° and 5.04° and images of transmission electron microscopy (TEM), respectively. For fabrication of mesoporous silica/alumina hybrid membrane, TPC10TEG/silicahex was drop-casted onto AAO membrane for penetration into the porous structure via gravity. X-ray diffraction (XRD) analysis on the resulted hybrid nanocomposites showed that the diffraction peaks of d 100 and d 200 of TPC10TEG/silicahex were still preserved, indicating that the hexagonal arrangements of mesoporous silica were maintained even on AAO substrate. The morphology study on the hybrid nanocomposites using TEM, scanning electron microscope (SEM) and field emission scanning electron microscope (FE-SEM) showed the successful filling of most AAO channels with the TPC10TEG/silicahex nanocomposites.

TWO PLANETARY COMPANIONS AROUND THE K7 DWARF GJ 221: A HOT SUPER-EARTH AND A CANDIDATE IN THE SUB-SATURN DESERT RANGE

Energy Technology Data Exchange (ETDEWEB)

Arriagada, Pamela; Minniti, Dante [Department of Astronomy, Pontificia Universidad Catolica de Chile, Casilla 306, Santiago 22 (Chile); Anglada-Escude, Guillem; Butler, R. Paul [Department of Terrestrial Magnetism, Carnegie Institution of Washington, 5241 Broad Branch Road NW, Washington, DC 20015-1305 (United States); Crane, Jeffrey D.; Shectman, Stephen A.; Thompson, Ian [The Observatories of the Carnegie Institution of Washington, 813 Santa Barbara Street, Pasadena, CA 91101 (United States); Wende, Sebastian, E-mail: parriaga@astro.puc.cl [Institut fuer Astrophysik, Universitaet Goettingen, Friedrich-Hund-Platz 1, D-37077 Goettingen (Germany)

2013-07-01

We report two low-mass companions orbiting the nearby K7 dwarf GJ 221 that have emerged from reanalyzing 4.4 yr of publicly available HARPS spectra complemented with 2 years of high-precision Doppler measurements with Magellan/PFS. The HARPS measurements alone contain the clear signal of a low-mass companion with a period of 125 days and a minimum mass of 53.2 M{sub Circled-Plus} (GJ 221b), falling in a mass range where very few planet candidates have been found (sub-Saturn desert). The addition of 17 PFS observations allows the confident detection of a second low-mass companion (6.5 M{sub Circled-Plus }) in a hot orbit (3.87 day period, GJ 221c). Spectroscopic and photometric calibrations suggest that GJ 221 is slightly depleted ([Fe/H] {approx} -0.1) compared to the Sun, so the presence of two low-mass companions in the system confirms the trend that slightly reduced stellar metallicity does not prevent the formation of planets in the super-Earth to sub-Saturn mass regime.

Training labels for hippocampal segmentation based on the EADC-ADNI harmonized hippocampal protocol.

Science.gov (United States)

Boccardi, Marina; Bocchetta, Martina; Morency, Félix C; Collins, D Louis; Nishikawa, Masami; Ganzola, Rossana; Grothe, Michel J; Wolf, Dominik; Redolfi, Alberto; Pievani, Michela; Antelmi, Luigi; Fellgiebel, Andreas; Matsuda, Hiroshi; Teipel, Stefan; Duchesne, Simon; Jack, Clifford R; Frisoni, Giovanni B

2015-02-01

The European Alzheimer's Disease Consortium and Alzheimer's Disease Neuroimaging Initiative (ADNI) Harmonized Protocol (HarP) is a Delphi definition of manual hippocampal segmentation from magnetic resonance imaging (MRI) that can be used as the standard of truth to train new tracers, and to validate automated segmentation algorithms. Training requires large and representative data sets of segmented hippocampi. This work aims to produce a set of HarP labels for the proper training and certification of tracers and algorithms. Sixty-eight 1.5 T and 67 3 T volumetric structural ADNI scans from different subjects, balanced by age, medial temporal atrophy, and scanner manufacturer, were segmented by five qualified HarP tracers whose absolute interrater intraclass correlation coefficients were 0.953 and 0.975 (left and right). Labels were validated as HarP compliant through centralized quality check and correction. Hippocampal volumes (mm(3)) were as follows: controls: left = 3060 (standard deviation [SD], 502), right = 3120 (SD, 897); mild cognitive impairment (MCI): left = 2596 (SD, 447), right = 2686 (SD, 473); and Alzheimer's disease (AD): left = 2301 (SD, 492), right = 2445 (SD, 525). Volumes significantly correlated with atrophy severity at Scheltens' scale (Spearman's ρ = segmentation algorithms. The publicly released labels will allow the widespread implementation of the standard segmentation protocol. Copyright © 2015 The Alzheimer's Association. Published by Elsevier Inc. All rights reserved.

Phosphorus content in three physical fractions of typical Chernozem

Science.gov (United States)

Kotelnikova, Anna; Egorova, Zoya; Sushkov, Nikolai; Matveeva, Natalia; Fastovets, Ilya; Rogova, Olga; Volkov, Dmitriy

2017-04-01

The widespread use of fertilizers makes it necessary to study not only the content but also the forms of occurrence of nutrients in soil, as well as the phase in which nutrients are transferred. These characteristics determine the availability of chemical elements for plants, but remain insufficiently studied. In this work we attempted to gain insight into the distribution of organo-mineral fractions in agriculturally used Chernozem from Voronezh (Russia) and the distribution of phosphorus - one of the most important nutrient elements - in this type of soil. We compared the distributions of phosphorus in physical fractions of the soil in 3 experimental groups: the control group (without fertilizers), the group fertilized with 1 dose of NPK, and the group fertilized with 2 doses of NPK. The soil was sampled during the period of treatment with fertilizers and during the period of aftereffect (4 years after the last application of fertilizers). In order to analyze organo-mineral fractions, we used size-density fractionation to separate the soil samples into three physical fractions: clay-associated fraction with particle size 2.0 g cm-3 (RF). Total phosphorus content (TPC) in the fractions was determined with Agilent 5100 ICP-AES spectrometer. To compare groups, simultaneous confidence intervals were computed from pooled variance estimators in ANOVA, and Fisher's LSD test was used. We showed that during the period of treatment with fertilizers LF increased proportionally to the dose of fertilizers, and a simultaneous reduction in RF was observed. During the period of aftereffect, the content of these fractions tended to the control value. The increase of LF may indicate increasing availability of nutrients, since this fraction is likely to participate in biological cycles. The analysis of TPC in fractions suggested that during the period of treatment with fertilizers most of phosphorus accumulates in CF. In the group with double dose of fertilizers TPC in CF was more

A Preliminary Study on Time Projection Chamber Simulation for Fission Cross Section Measurements with Geant4

International Nuclear Information System (INIS)

Kim, Jong Woon; Lee, Youngouk; Kim, Jae Cheon

2014-01-01

We present the details of the TPC simulation with Geant4 and show the results. TPC can provide more information than a fission chamber in that it is possible to distinguish different particle types. Simulations are conducted for uranium and plutonium targets with 20MeV neutrons. The simulation results are compared with the reference and show reasonable results. This is the first phase of study for realizing a TPC in the NFS at RAON, and we have more work to do, such as applying an electric field, signal processing in the simulation, and manufacturing of a TPC. The standard in fission cross section measurement is a fission chamber. It is basically just two parallel plates separated by a few centimeters of gas. A power supply connected to the plates sets up a moderate electric field. The target is deposited onto one of the plates. When fission occurs, the fragments ionize the gas, and the electric field causes the produced electrons to drift to the opposite plate, which records the total energy deposited in the chamber. A Time Projection Chamber (TPC) is a gas ionization detector similar to a fission chamber. However, it can measure the charged particle trajectories in the active volume in three dimensions by adding several readouts on the pad plane (fission chamber has only one readout one a pad plane). The specific ionization for each particle track enables the TPC to distinguish different particle types. A TPC will be used for fission cross section measurements in the Neutron Science Facility (NSF) at RAON. As a preliminary study, we present details of TPC simulation with Geant4 and discuss the results

Evaluation of chemical characteristics and correlation analysis with pulp browning of advanced selections of apples grown in Brazil

Directory of Open Access Journals (Sweden)

Luciana Ercoli

2017-02-01

Full Text Available In this research, the total phenolic content (TPC and antioxidant capacity (FRAP and DPPH•× assays of pulps and peels of advanced selection of apples grown in Brazil were investigated. The correlation analyses between the activity of polyphenoloxidase enzyme (PPO, vitamin C content, total titratable acidity, and color parameters were performed. The results indicated that the data differed significantly among the apple genotypes studied. The peels of the selection Epagri 170-91 and Epagri 170-25 showed the highest TPC and antioxidant capacities. In addition, the pulps of the Epagri 170-91 presented the highest TPC and antioxidant capacities, the lowest enzymatic browning, highest amount of vitamin C and lowest enzymatic activity when compared with other genotypes. The TPC and antioxidant capacities were significantly correlated in all genotypes analyzed. High correlation values between enzymatic browning and factors that affect the apple color were also found in all analyzed pulps, except between enzymatic browning and TPC. The results demonstrated that the enzymatic browning and TPC, as well as the antioxidant capacity and chemical characteristics, vary considerably depending on the apple genotypes and fruit tissues analyzed.

Increased synthesis of heparin affin regulatory peptide in the perforant path lesioned mouse hippocampal formation

DEFF Research Database (Denmark)

Poulsen, F R; Lagord, C; Courty, J

2000-01-01

differentiation in vivo. Here we have investigated the expression of HARP mRNA and protein in the perforant path lesioned C57B1/6 mouse hippocampal formation from 1 to 35 days after surgery. This type of lesion induces a dense anterograde and terminal axonal degeneration, activation of glial cells, and reactive...... axonal sprouting within the perforant path zones of the fascia dentata and hippocampus as well as axotomy-induced retrograde neuronal degeneration in the entorhinal cortex. Analysis of sham- and unoperated control mice showed that HARP mRNA is expressed in neurons and white and gray matter glial cells...... as well as vascular and pial cells throughout the normal, adult brain. Lesioning induced high levels of HARP mRNA in astroglial-like cells in the denervated zones of fascia dentata and hippocampus as soon as day 2 postlesion. This expression reached maximum at day 4, and declined toward normal at day 7...

ALICE comes to life

CERN Multimedia

2002-01-01

On 26 March, a first major part of the ALICE detector arrived at CERN: one of the four cylinders in composite material for the Time Projection Chamber (TPC). The construction of the TPC 'field cage' (the structure that defines the configuration of the electrical field of the TPC) is the fruit of exceptional collaboration between CERN and the Austrian manufacturer Fischer Advanced Composite Components (Fischer ACC).

Study of the machine background induced by the PEP-II collider with a mini-TPC. Study of the doubly-charmed decay of the B meson with the detector BaBar

International Nuclear Information System (INIS)

Trincaz-Duvoid, S.

2001-01-01

The work presented in this thesis is divided into two parts. The first one deals with the machine background induced by the PEP-II collider. This study has been performed with a mini-TPC before the start of the BaBar experiment. The second part concerns the measurements of the branching ratio of the decay modes B 0 → D *- D(*) 0 K + and of the inclusive branching ratio Br(B 0 → K ± X). These measurements have been obtained with the first BaBar data. During the commissioning of the PEP-II collider, the charged tracks rate close to the interaction point has been measured with the mini-TPC. This study has pointed to the fact that the machine background was much higher than predicted by the simulation. These bad background conditions were due to the poor quality of the vacuum in the rings. This relatively high pressure in the rings produces electro-magnetic showers at the interaction point due to beam gas interactions. The potential risks for the BaBar detector due to the machine backgrounds have been clearly pointed out by the studies performed for this thesis. The addition of some collimators and a deep understanding of the machine have greatly reduced the background. Nevertheless, the radiation level in BaBar is continuously monitored in order to protect the detector. The study of the b → cc-bar channel is an important point for the understanding of the overall picture of the B meson decay. With an integrated luminosity of 17.3 fb -1 recorded by the BaBar detector the following branching ratio using exclusive reconstruction technique have been measured: Br(B 0 → D *- D 0 K + ) = (0.29 ± 0.06 (stat) ± (syst)) % Br(B 0 → D *- D *0 K + ) = (1.16 ± 0.15 (stat) ± 0.16 (syst)) % A partial reconstruction has also been developed. With an integrated luminosity of 8.9 fb -1 , the branching ratio of B 0 into D *- D 0 K + has been measured: Br(B 0 → D *- D 0 K + ) = (0.45 ± 0.12 (stat) ± 0.25 (syst)) % This result is in good agreement with the value obtained

The impact of red noise in radial velocity planet searches: only three planets orbiting GJ 581?

Science.gov (United States)

Baluev, Roman V.

2013-03-01

We perform a detailed analysis of the latest HARPS and Keck radial velocity data for the planet-hosting red dwarf GJ 581, which attracted a lot of attention in recent time. We show that these data contain important correlated noise component (`red noise') with the correlation time-scale of the order of 10 d. This red noise imposes a lot of misleading effects while we work in the traditional white-noise model. To eliminate these misleading effects, we propose a maximum-likelihood algorithm equipped by an extended model of the noise structure. We treat the red noise as a Gaussian random process with an exponentially decaying correlation function. Using this method we prove that (i) planets b and c do exist in this system, since they can be independently detected in the HARPS and Keck data, and regardless of the assumed noise models; (ii) planet e can also be confirmed independently by both the data sets, although to reveal it in the Keck data it is mandatory to take the red noise into account; (iii) the recently announced putative planets f and g are likely just illusions of the red noise; (iv) the reality of the planet candidate GJ 581 d is questionable, because it cannot be detected from the Keck data, and its statistical significance in the HARPS data (as well as in the combined data set) drops to a marginal level of ˜2σ, when the red noise is taken into account. Therefore, the current data for GJ 581 really support the existence of no more than four (or maybe even only three) orbiting exoplanets. The planet candidate GJ 581 d requests serious observational verification.

Principal Component Analysis of Stimulatory Effect of Synbiotic Combination of Indigenous Probiotic and Inulin on Antioxidant Activity of Soymilk.

Science.gov (United States)

Choudhary, Shagun; Singh, Manisha; Sharma, Deepak; Attri, Sampan; Sharma, Kavita; Goel, Gunjan

2018-06-02

The present study aimed to screen the indigenous probiotic cultures for their effect on total phenolic contents (TPC) and associated antioxidant activities in synbiotic fermented soymilk during storage. Among 16 cultures, subtractive screening was conducted based on different tests such as acidification rate and proliferation of lactic acid bacteria (LAB) on supplementation of inulin (0-20 mM) and fructooligosaccharide (0-0.45 mM). Lactobacillus paracasei CD4 was selected as potential strain after principal component analysis (PCA) of different strains with prebiotic substrates at different concentrations. The strain was used for production of synbiotic soymilk product containing 10 mM inulin. The storage study was conducted at 4 °C for 21 days. During storage, the pH, titratable acidity, TPC, antioxidant activities, and viable cell counts (VCC) were determined. The fermentation of soymilk supplemented with 10 mM inulin did not alter the VCC; however, a decrease in pH and TPC and an increase in acidity and antioxidant activity were observed (p inulin in soymilk enhanced the viability of Lactobacillus paracasei CD4 and antioxidant activity during storage under refrigeration conditions.

Evaluation of seven different drying treatments in respect to total flavonoid, phenolic, vitamin C content, chlorophyll, antioxidant activity and color of green tea (Camellia sinensis or C. assamica) leaves.

Science.gov (United States)

Roshanak, Sahar; Rahimmalek, Mehdi; Goli, Sayed Amir Hossein

2016-01-01

The effect of seven drying treatments (sun, shade, oven 60 °C, oven 80 °C, oven 100 °C, microwave and freeze-drying) were evaluated with respect total flavonoid (TFC), phenolic (TPC), antioxidant activity, vitamin C and color characteristics of green tea. In general, drying increased antioxidant activity, TPC, TFC and chlorophyll content, while it led to a decrease in vitamin C. The highest TPC (209.17 mg Gallic acid/gdw) and TFC (38.18 mg Quercitin/gdw) were obtained in oven drying at 60 and 100 °C, respectively. Among methods, oven drying at 60 °C revealed the highest radical scavenging activity (IC50 = 167.166 μg/ml), while microwave showed the lowest one (IC50 = 505.5 μg/ml). Similar trend was also observed in reducing power assay. The highest vitamin C (16.36 mg/100gDM) and Chlorophyll a (17.35 mg/l) were obtained in freeze drying. Finally, sun and freeze drying methods were considered as the least and the most desirable drying methods, respectively the final color of green tea leaves.

Antioxidant properties of chemical extracts and bioaccessible fractions obtained from six Spanish monovarietal extra virgin olive oils: assays in Caco-2 cells.

Science.gov (United States)

Borges, Thays H; Cabrera-Vique, Carmen; Seiquer, Isabel

2015-07-01

The antioxidant activity and the total phenolic content (TPC) of six Spanish commercial monovarietal extra virgin olive oils (Arbequina, Cornicabra, Hojiblanca, Manzanilla, Picual and Picudo) were evaluated in chemical extracts and in bioaccessible fractions (BF) obtained after in vitro digestion. Moreover, the effects of the BF on cell viability and the generation of reactive oxygen species (ROS) were investigated in Caco-2 cell cultures. The in vitro digestion process increased the TPC and antioxidant activity evaluated by different methods (ABTS, DPPH and FRAP) compared with chemical extracts. After digestion, the Picual variety showed better beneficial effects in preserving cell integrity than the other varieties studied. Significant reductions of ROS production were observed after incubation of Caco-2 cells with the BF of all the varieties and, moreover, a protective effect against the oxidative stress induced by t-BOOH was shown for Arbequina, Cornicabra, Hojiblanca, Manzanilla and Picual. These findings seem to be an additional reason supporting the health benefits of Spanish extra virgin olive oil varieties. Multivariate factor analysis and principal component analysis were applied to assess the contribution of antioxidant activity and TPC, before and after digestion, to the characterization of the different varieties.

Novel Front-end Electronics for Time Projection Chamber Detectors

CERN Document Server

García García, Eduardo José

This work has been carried out in the European Organization for Nuclear Research (CERN) and it was supported by the European Union as part of the research and development towards the European detector the (EUDET) project, specifically for the International Linear Collider (ILC). In particle physics there are several different categories of particle detectors. The presented design is focused on a particular kind of tracking detector called Time Projection Chamber (TPC). The TPC provides a three dimensional image of electrically charged particles crossing a gaseous volume. The thesis includes a study of the requirements for future TPC detectors summarizing the parameters that the front-end readout electronics must fulfill. In addition, these requirements are compared with respect to the readouts used in existing TPC detectors. It is concluded that none of the existing front-end readout designs fulfill the stringent requirements. The main requirements for future TPC detectors are high integration, an increased n...

Optimisation of Ultrasound-Assisted Extraction Conditions for Phenolic Content and Antioxidant Capacity from Euphorbia tirucalli Using Response Surface Methodology

Science.gov (United States)

Vuong, Quan V.; Goldsmith, Chloe D.; Dang, Trung Thanh; Nguyen, Van Tang; Bhuyan, Deep Jyoti; Sadeqzadeh, Elham; Scarlett, Christopher J.; Bowyer, Michael C.

2014-01-01

Euphorbia tirucalli (E. tirucalli) is now widely distributed around the world and is well known as a source of traditional medicine in many countries. This study aimed to utilise response surface methodology (RSM) to optimise ultrasonic-assisted extraction (UAE) conditions for total phenolic compounds (TPC) and antioxidant capacity from E. tirucalli leaf. The results showed that ultrasonic temperature, time and power effected TPC and antioxidant capacity; however, the effects varied. Ultrasonic power had the strongest influence on TPC; whereas ultrasonic temperature had the greatest impact on antioxidant capacity. Ultrasonic time had the least impact on both TPC and antioxidant capacity. The optimum UAE conditions were determined to be 50 °C, 90 min. and 200 W. Under these conditions, the E. tirucalli leaf extract yielded 2.93 mg GAE/g FW of TPC and exhibited potent antioxidant capacity. These conditions can be utilised for further isolation and purification of phenolic compounds from E. tirucalli leaf. PMID:26785074

Prototype ALICE front-end card

CERN Multimedia

Maximilien Brice

2004-01-01

This circuit board is a prototype 48-channel front end digitizer card for the ALICE time projection chamber (TPC), which takes electrical signals from the wire sensors in the TPC and shapes the data before converting the analogue signal to digital data. A total of 4356 cards will be required to process the data from the ALICE TPC, the largest of this type of detector in the world.

ALICE presents its first award to Industry

CERN Multimedia

Maximilien Brice

2003-01-01

Behind from left to right (Derrière de gauche à droite): Bernardo Mota, member of the ALTRO design team, Jurgen Schukraft, ALICE Spokesperson, Luciano Musa, leader of the ALTRO Design Team and Coordinator of the ALICE TPC FEE, Roberto Camapagnolo, member of the ALICE TPC FEE team, Jean-Pierre Coffin, Deputy of the ALICE Collaboration Board Chairman, Hans de Groot ALICE Resource Coordinator, Laurent Degoujon, ST - Data Converter Design Manager, Claude Engster, member of the ALICE TPC FEE team, Alain Delpi, ST - Data Converter Business Unit Manager, Carmen Gonzalez, member of the ALICE TPC FEE team, Yiota Foka, ALICE Outreach Coordinator; Front: Fabio Formenti , EP-ED Group Leader, Juan Antonio Rubio, ETT Division Leader.

HARP MHI- Cross Seamount

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — PIFSC and Scripps Institution of Oceanography (SIO) conducted passive acoustic monitoring for cetaceans at Cross Seamount in 2005 and 2006 using a High-Frequency...

Reduction of seismic response long-span PC cable-stayed bridge by passive dampers; Damper ni yoru saidai PC shachokyo no jishinji oto no teigen

Energy Technology Data Exchange (ETDEWEB)

Takeda, T.; Yamanobe, S.; Niihara, Y. [Kajima Corp., Tokyo (Japan)

1994-10-31

It is important in designing a PC cable-stayed bridge to properly estimate the seismic response of the bridge for reduction of the response. In this paper, an improvement of the seismic resistance of PC cable-stayed bridges when dampers are installed between the deck and piers and lateral vibration of the deck is restricted is investigated using a time history response model. PC cable-stayed bridges with a span length of 400 m, particularly two types of bridges of harp and semi-harp are investigated and the following is found by analyzing the case where there are installed hysteresis type dampers (with 1 cm yield displacement and secondary rigidity assumed to be 1/10 times that of initial rigidity, the initial rigidity being parametrically changed.) or viscous type dampers (a damping factor is changed.) The result shows that the dampers can reduce the seismic response of a PC cable-stayed bridge and that a semi-harp configuration of stay cables where stay cable members are substantially vertically arranged is more effective than a harp configuration for the seismic performance of PC cable-stayed bridges. The damper partly bear inertial force of the bridge upon earthquake whereby tension of the stay cable members is reduced and bending moment of the deck is reduced. There is existing an optimum characteristic value of the damper concerning the bending moment of the piers. 5 refs., 7 figs., 2 tabs.

Operation of a GEM-TPC with pixel readout

CERN Document Server

Brezina, C; Kaminski, J; Killenberg, M; Krautscheid, T

2012-01-01

A prototype time projection chamber with 26 cm drift length was operated with a short-spaced triple gas electron multiplier (GEM) stack in a setup triggering on cosmic muon tracks. A small part of the anode plane is read out with a CMOS pixel application-specified integrated circuit (ASIC) named Timepix, which provides ultimate readout granularity. Pixel clusters of charge depositions corresponding to single primary electrons are observed and analyzed to reconstruct charged particle tracks. A dataset of several weeks of cosmic ray data is analyzed. The number of clusters per track length is well described by simulation. The obtained single point resolution approaches 50 m at short drift distances and is well reproduced by a simple model of single-electron diffusion.

Two-dimensional beam profiles and one-dimensional projections

Science.gov (United States)

Findlay, D. J. S.; Jones, B.; Adams, D. J.

2018-05-01

One-dimensional projections of improved two-dimensional representations of transverse profiles of particle beams are proposed for fitting to data from harp-type monitors measuring beam profiles on particle accelerators. Composite distributions, with tails smoothly matched on to a central (inverted) parabola, are shown to give noticeably better fits than single gaussian and single parabolic distributions to data from harp-type beam profile monitors all along the proton beam transport lines to the two target stations on the ISIS Spallation Neutron Source. Some implications for inferring beam current densities on the beam axis are noted.

Characterization of the K2-18 multi-planetary system with HARPS. A habitable zone super-Earth and discovery of a second, warm super-Earth on a non-coplanar orbit

Science.gov (United States)

Cloutier, R.; Astudillo-Defru, N.; Doyon, R.; Bonfils, X.; Almenara, J.-M.; Benneke, B.; Bouchy, F.; Delfosse, X.; Ehrenreich, D.; Forveille, T.; Lovis, C.; Mayor, M.; Menou, K.; Murgas, F.; Pepe, F.; Rowe, J.; Santos, N. C.; Udry, S.; Wünsche, A.

2017-12-01

Aims: The bright M2.5 dwarf K2-18 (Ms = 0.36 M⊙, Rs = 0.41 R⊙) at 34 pc is known to host a transiting super-Earth-sized planet orbiting within the star's habitable zone; K2-18b. Given the superlative nature of this system for studying an exoplanetary atmosphere receiving similar levels of insolation as the Earth, we aim to characterize the planet's mass which is required to interpret atmospheric properties and infer the planet's bulk composition. Methods: We have obtained precision radial velocity measurements with the HARPS spectrograph. We then coupled those measurements with the K2 photometry to jointly model the observed radial velocity variation with planetary signals and a correlated stellar activity model based on Gaussian process regression. Results: We measured the mass of K2-18b to be 8.0 ± 1.9M⊕ with a bulk density of 3.3 ± 1.2 g/cm3 which may correspond to a predominantly rocky planet with a significant gaseous envelope or an ocean planet with a water mass fraction ≳50%. We also find strong evidence for a second, warm super-Earth K2-18c (mp,csinic = 7.5 ± 1.3 M⊕) at approximately nine days with a semi-major axis 2.4 times smaller than the transiting K2-18b. After re-analyzing the available light curves of K2-18 we conclude that K2-18c is not detected in transit and therefore likely has an orbit that is non-coplanar with the orbit of K2-18b although only a small mutual inclination is required for K2-18c to miss a transiting configuration; | Δi| 1-2°. A suite of dynamical integrations are performed to numerically confirm the system's dynamical stability. By varying the simulated orbital eccentricities of the two planets, dynamical stability constraints are used as an additional prior on each planet's eccentricity posterior from which we constrain eb multi-planet systems around M dwarfs. The characterization of the density of K2-18b reveals that the planet likely has a thick gaseous envelope which, along with its proximity to the solar

A Three-Port Topology Comparison for a Low Power Stand-Alone Photovoltaic System

DEFF Research Database (Denmark)

Mira Albert, Maria del Carmen; Knott, Arnold; Andersen, Michael A. E.

2014-01-01

Three-port converter (TPC) topologies for renewable energy systems aim to provide higher efficiency and power density than conventional cascaded structures. This work proposes an analytical comparison of different TPC topologies for a photovoltaic LED lamp stand-alone system. A comparison using c...... component stress factor (CSF) is performed, which gives a quantitative measure of the performance of the converter. The candidate topologies are compared to each other according to a defined LED lighting strategy and a solar irradiation profile.......Three-port converter (TPC) topologies for renewable energy systems aim to provide higher efficiency and power density than conventional cascaded structures. This work proposes an analytical comparison of different TPC topologies for a photovoltaic LED lamp stand-alone system. A comparison using...

Study of the machine background induced by the PEP-II collider with a mini-TPC. Study of the doubly-charmed decay of the B meson with the detector BaBar; Etude du bruit de fond engendre par la machine PEP-2 a l'aide d'une mini-TPC. Etude de la desintegration doublement charmee du meson B avec le detecteur BaBar

Energy Technology Data Exchange (ETDEWEB)

Trincaz-Duvoid, S

2001-01-01

The work presented in this thesis is divided into two parts. The first one deals with the machine background induced by the PEP-II collider. This study has been performed with a mini-TPC before the start of the BaBar experiment. The second part concerns the measurements of the branching ratio of the decay modes B{sup 0} {yields} D{sup *-}D(*){sup 0}K{sup +} and of the inclusive branching ratio Br(B{sup 0} {yields} K{sup {+-}}X). These measurements have been obtained with the first BaBar data. During the commissioning of the PEP-II collider, the charged tracks rate close to the interaction point has been measured with the mini-TPC. This study has pointed to the fact that the machine background was much higher than predicted by the simulation. These bad background conditions were due to the poor quality of the vacuum in the rings. This relatively high pressure in the rings produces electro-magnetic showers at the interaction point due to beam gas interactions. The potential risks for the BaBar detector due to the machine backgrounds have been clearly pointed out by the studies performed for this thesis. The addition of some collimators and a deep understanding of the machine have greatly reduced the background. Nevertheless, the radiation level in BaBar is continuously monitored in order to protect the detector. The study of the b {yields} cc-bar channel is an important point for the understanding of the overall picture of the B meson decay. With an integrated luminosity of 17.3 fb{sup -1} recorded by the BaBar detector the following branching ratio using exclusive reconstruction technique have been measured: Br(B{sup 0} {yields} D{sup *-}D{sup 0}K{sup +}) = (0.29 {+-} 0.06 (stat) {+-} (syst)) % Br(B{sup 0} {yields} D{sup *-}D{sup *0}K{sup +}) = (1.16 {+-} 0.15 (stat) {+-} 0.16 (syst)) % A partial reconstruction has also been developed. With an integrated luminosity of 8.9 fb{sup -1}, the branching ratio of B{sup 0} into D{sup *-}D{sup 0}K{sup +} has been measured

Electronically active defects in the Cu2ZnSn(Se,S)4 alloys as revealed by transient photocapacitance spectroscopy

Science.gov (United States)

Miller, D. Westley; Warren, Charles W.; Gunawan, Oki; Gokmen, Tayfun; Mitzi, David B.; Cohen, J. David

2012-10-01

Transient photocapacitance (TPC) spectra were obtained on a series of Cu2ZnSn(Se,S)4 absorber devices with varying Se:S ratios, providing bandgaps (Eg) between 1 eV and 1.5 eV. Efficiencies varied between 8.3% and 9.3% for devices with Eg ≤ 1.2 eV and were near 6.5% for devices with Eg ≥ 1.4 eV. The TPC spectra revealed a band-tail region with Urbach energies at or below 18 meV for the first group, but in the 25-30 meV range for the higher band-gap samples. A deeper defect band centered near 0.8 eV was also observed in most samples. We identified a correlation between the Urbach energies and the voltage deficit in these devices.

An image-guided radiotherapy decision support framework incorporating a Bayesian network and visualization tool.

Science.gov (United States)

Hargrave, Catriona; Deegan, Timothy; Bednarz, Tomasz; Poulsen, Michael; Harden, Fiona; Mengersen, Kerrie

2018-05-17

To describe a Bayesian network (BN) and complementary visualization tool that aim to support decision-making during online cone-beam computed tomography (CBCT)-based image-guided radiotherapy (IGRT) for prostate cancer patients. The BN was created to represent relationships between observed prostate, proximal seminal vesicle (PSV), bladder and rectum volume variations, an image feature alignment score (FAS TV _ OAR ), delivered dose, and treatment plan compliance (TPC). Variables influencing tumor volume (TV) targeting accuracy such as intrafraction motion, and contouring and couch shift errors were also represented. A score of overall TPC (FAS global ) and factors such as image quality were used to inform the BN output node providing advice about proceeding with treatment. The BN was quantified using conditional probabilities generated from published studies, FAS TV _ OAR /global modeling, and a survey of IGRT decision-making practices. A new IGRT visualization tool (IGRT REV ), in the form of Mollweide projection plots, was developed to provide a global summary of residual errors after online CBCT-planning CT registration. Sensitivity and scenario analyses were undertaken to evaluate the performance of the BN and the relative influence of the network variables on TPC and the decision to proceed with treatment. The IGRT REV plots were evaluated in conjunction with the BN scenario testing, using additional test data generated from retrospective CBCT-planning CT soft-tissue registrations for 13/36 patients whose data were used in the FAS TV _ OAR /global modeling. Modeling of the TV targeting errors resulted in a very low probability of corrected distances between the CBCT and planning CT prostate or PSV volumes being within their thresholds. Strength of influence evaluation with and without the BN TV targeting error nodes indicated that rectum- and bladder-related network variables had the highest relative importance. When the TV targeting error nodes were excluded

Electronic structure of the dilute magnetic semiconductor G a1 -xM nxP from hard x-ray photoelectron spectroscopy and angle-resolved photoemission

Science.gov (United States)

Keqi, A.; Gehlmann, M.; Conti, G.; Nemšák, S.; Rattanachata, A.; Minár, J.; Plucinski, L.; Rault, J. E.; Rueff, J. P.; Scarpulla, M.; Hategan, M.; Pálsson, G. K.; Conlon, C.; Eiteneer, D.; Saw, A. Y.; Gray, A. X.; Kobayashi, K.; Ueda, S.; Dubon, O. D.; Schneider, C. M.; Fadley, C. S.

2018-04-01

We have investigated the electronic structure of the dilute magnetic semiconductor (DMS) G a0.98M n0.02P and compared it to that of an undoped GaP reference sample, using hard x-ray photoelectron spectroscopy (HXPS) and hard x-ray angle-resolved photoemission spectroscopy (HARPES) at energies of about 3 keV. We present experimental data, as well as theoretical calculations, to understand the role of the Mn dopant in the emergence of ferromagnetism in this material. Both core-level spectra and angle-resolved or angle-integrated valence spectra are discussed. In particular, the HARPES experimental data are compared to free-electron final-state model calculations and to more accurate one-step photoemission theory. The experimental results show differences between G a0.98M n0.02P and GaP in both angle-resolved and angle-integrated valence spectra. The G a0.98M n0.02P bands are broadened due to the presence of Mn impurities that disturb the long-range translational order of the host GaP crystal. Mn-induced changes of the electronic structure are observed over the entire valence band range, including the presence of a distinct impurity band close to the valence-band maximum of the DMS. These experimental results are in good agreement with the one-step photoemission calculations and a prior HARPES study of G a0.97M n0.03As and GaAs [Gray et al., Nat. Mater. 11, 957 (2012), 10.1038/nmat3450], demonstrating the strong similarity between these two materials. The Mn 2 p and 3 s core-level spectra also reveal an essentially identical state in doping both GaAs and GaP.

Textpresso Central: a customizable platform for searching, text mining, viewing, and curating biomedical literature.

Science.gov (United States)

Müller, H-M; Van Auken, K M; Li, Y; Sternberg, P W

2018-03-09

The biomedical literature continues to grow at a rapid pace, making the challenge of knowledge retrieval and extraction ever greater. Tools that provide a means to search and mine the full text of literature thus represent an important way by which the efficiency of these processes can be improved. We describe the next generation of the Textpresso information retrieval system, Textpresso Central (TPC). TPC builds on the strengths of the original system by expanding the full text corpus to include the PubMed Central Open Access Subset (PMC OA), as well as the WormBase C. elegans bibliography. In addition, TPC allows users to create a customized corpus by uploading and processing documents of their choosing. TPC is UIMA compliant, to facilitate compatibility with external processing modules, and takes advantage of Lucene indexing and search technology for efficient handling of millions of full text documents. Like Textpresso, TPC searches can be performed using keywords and/or categories (semantically related groups of terms), but to provide better context for interpreting and validating queries, search results may now be viewed as highlighted passages in the context of full text. To facilitate biocuration efforts, TPC also allows users to select text spans from the full text and annotate them, create customized curation forms for any data type, and send resulting annotations to external curation databases. As an example of such a curation form, we describe integration of TPC with the Noctua curation tool developed by the Gene Ontology (GO) Consortium. Textpresso Central is an online literature search and curation platform that enables biocurators and biomedical researchers to search and mine the full text of literature by integrating keyword and category searches with viewing search results in the context of the full text. It also allows users to create customized curation interfaces, use those interfaces to make annotations linked to supporting evidence statements

Antioxidant Activity and the relationship with Panholic Composition in some Egyptian Pomegranate Cultivars

International Nuclear Information System (INIS)

Mahmoud, K.A.; Ibrahim, G.E.

2013-01-01

Pomegranate fruit is an important source of potentially healthy bioactive compounds. Changes in total phenolic content, phenolic compounds and anti radical activity in juice and peel extracts of pomegranate fruit of five cultivars were studied. Total phenolic content (TPC) varied between 1598.96 and 2315.10 mg gallic acid L-1 for pulp juice while TPC ranged from 8.68 to 15.46 mg/g in peel extract. All cultivars juice and peel extracts undertaken had a high capacity while TPC changed from 8.68 to 15.94 mg gallic acid scavenge 1,1-diphenyl-2-picrylhydrazyl (DPPH0) and β- carotene assays Increasing the concentration of either pomegranate juice (PJ) or peel extract increased (P < 0.05) the radical scavenging activity, however anti radical activity of peel extracts was higher than juice one. A good correlation between phenolic content and the radical scavenging activities was observed higher in peel extract than fruit juice. According to the results of high performance liquid chromatography (HPLC), the gallic acids, chlorogenic acid and caffeic were the predominant phenolic compounds of the pomegranate cultivars. We concluded that pomegranate peel extract and juice appeared to have more potential as a health supplement rich in natural antioxidants than the pulp extract and merits and need further intensive study.

Studies of field distortions in a time projection chamber for the International Linear Collider

International Nuclear Information System (INIS)

Zenker, Klaus

2014-12-01

The International Linear Collider (ILC) will allow to do precision measurements of Standard Model parameter and to search for new physics. The ILD detector concept, which is developed for the ILC, uses a Time Projection Chamber (TPC) as central tracking device. The momentum resolution goal for the ILD TPC is δ(1/p t ) ≅ 10 -4 (GeV/c) -1 at a magnetic field of B=3.5 T. Field distortions of the magnetic or electric field inside the sensitive volume of the TPC distort the momentum measurements. Therefore, one needs to keep them under control and correct them with high precision. In this thesis the main sources of field distortions in the TPC are identified and their effects are determined. Furthermore, possibilities to reduce the identified field distortions are presented. One known source of distortions of the electric field are ions, produced by the gas amplification in the TPC anode, that drift into the sensitive volume of the TPC. In the first part of this work the creation of these ions in Gas Electron Multiplier (GEM), which are used for the gas amplification, is studied. It will be shown that the resulting field distortions are not acceptable at the ILD TPC. By tuning the parameters of the gas amplification at the anode the field distortion can be reduced, which is shown in measurements and simulations. In addition measurements using a modified GEM show that it is possible to further reduce the field distortions with such a GEM. In the second part of this work field distortions arising at boundaries between individual readout modules are investigated using simulation studies. It will be shown in simulations, which are verified by measurement results, that these field distortions significantly influence the readout module performance. Based on the simulation results the GEM based readout module developed at DESY is optimised and the field distortions are reduced. These performance improvements could also be verified in measurements. Finally, a laser

Track distortion in a micromegas based large prototype of a Time Projection Chamber for the International Linear Collider

International Nuclear Information System (INIS)

Bhattacharya, Deb Sankar; Majumdar, Nayana; Sarkar, S.; Bhattacharya, S.; Mukhopadhyay, Supratik; Bhattacharya, P.; Attie, D.; Colas, P.; Ganjour, S.; Bhattacharya, Aparajita

2016-01-01

The principal particle tracker at the International Linear Collider (ILC) is planned to be a large Time Projection Chamber (TPC) where different Micro Pattern Gaseous Detector (MPGDs) candidate as the gaseous amplifier. A Micromegas (MM) based TPC can meet the ILC requirement of continuous and precise pattern recognition. Seven MM modules, working as the end-plate of a Large Prototype TPC (LPTPC) installed at DESY, have been tested with a 5 GeV electron beam. Due to the grounded peripheral frame of the MM modules, at low drift, the electric field lines near the detector edge remain no longer parallel to the TPC axis. This causes signal loss along the boundaries of the MM modules as well as distortion in the reconstructed track. In presence of magnetic field, the distorted electric field introduces ExB effect

Study of bifurcation behavior of two-dimensional turbo product code decoders

International Nuclear Information System (INIS)

He Yejun; Lau, Francis C.M.; Tse, Chi K.

2008-01-01

Turbo codes, low-density parity-check (LDPC) codes and turbo product codes (TPCs) are high performance error-correction codes which employ iterative algorithms for decoding. Under different conditions, the behaviors of the decoders are different. While the nonlinear dynamical behaviors of turbo code decoders and LDPC decoders have been reported in the literature, the dynamical behavior of TPC decoders is relatively unexplored. In this paper, we investigate the behavior of the iterative algorithm of a two-dimensional TPC decoder when the input signal-to-noise ratio (SNR) varies. The quantity to be measured is the mean square value of the posterior probabilities of the information bits. Unlike turbo decoders or LDPC decoders, TPC decoders do not produce a clear 'waterfall region'. This is mainly because the TPC decoding algorithm does not converge to 'indecisive' fixed points even at very low SNR values

Possible physics program with a large acceptance hyperon spectrometer at J-PARC

International Nuclear Information System (INIS)

Imai, Kenichi

2013-01-01

We are going to construct a large acceptance hyperon spectrometer (HypTPC) at J-PARC primarily to search for H-dibaryon. The HypTPC consists of a superconducting Helmholtz magnet and a Time Projection Chamber (TPC). The short-life hyperons can be detected with high precision as well as any charged particles. Here, we discuss possible physics programs other than H-dibaryon which can be done with this spectrometer, such as a nucleon resonance spectroscopy experiment, systematic study of Λ(1405) and spectroscopy of Ξ and Ω - resonances. (author)

Construction work of superstructure of twin harp bridge. Twin harp kyo jobuko no seko

Energy Technology Data Exchange (ETDEWEB)

Sasaki, H.; Sato, Y.; Kanazawa, Y. (Sumitomo Construction Kajima Corp. Dopy Construction Co. Ltd. Nihon Koatsu Concrete Co. Ltd. Joint Venture, Tokyo (Japan)); Sema, M. (Sumitomo Construction Co. Ltd., Tokyo (Japan))

1991-11-30

Construction plan outline of PC cable stayed bridge with main tower having one pillar structure is introduced and this is the first type of bridge in Japan with three continuous span design. Construction was commenced on 7 July, 1989 and was completed on 8 August, 1991 at south east of Ashahikawa, Hokkaido. Construction outline is consisted of Principal specifications, general layout of structure, construction order and overall stage of the construction work. Main tower is described by its outline, jump system, installation of diagonal member anchorage device, formwork and concrete structure, and cross beam construction has included four parts which are outline, capital part, projected part construction, lateral span and closure part, and central control span and closure part. Outline, cable guard and erection work, cable work, work Procedure of cable taut construction using total taut method, tension adjustment of cable and grouting, for diagonal member are explained. The construction control items specific to cable stayed bridge are diagonal member tension control( control of applied tension, change of tension with time and test taut ) and camber control. Practical vibration test was carried out on March, 1991. 8 refs., 15 figs., 5 tabs.

ARIADNE: Beam Time and Resources Request - Addendum

CERN Document Server

Hollywood, D; Mavrokoridis, K; McCormick, KJ; Philippou, B; Roberts, A; Stavrakis, G; Touramanis, C; Vann, J

2017-01-01

This addendum provides additional information and clarification requested by the SPS Committee in response to our previously submitted Beam Time Request (CERN-SPSC-2017-031 [SPSC-P-356]). The ARIADNE research programme is based around developing an optical readout system for use in LAr TPC detectors, which could potentially have a number of benefits over the currently used segmented anode planes - particularly in matters of scalability for future kilo-tonne scale detectors, ease of installation, use and maintenance, and reconstruction resolution. As detailed in our previously submitted Letter of Intent (CERN-SPSC-2016-008 [SPSC-I-244]), ARIADNE itself is a 1-tonne, two-phase LAr TPC detector, designed and built at the University of Liverpool, which uses an array of EMCCD cameras as its optical readout system, alongside PMTs for scintillation light observation and a segmented THGEM for charge readout.

Survival of Listeria monocytogenes and Salmonella typhimurium and quality attributes of cooked pork chops and cured ham after irradiation

International Nuclear Information System (INIS)

Fu, A.H.; Sebranek, J.G.; Murano, E.A.

1995-01-01

Cooked pork chops (pumped with salt/polyphosphate brine or untreated) and cured hams were inoculated with Listeria monocytogenes and Salmonella typhimurium. The samples were irradiated at low (0.75 to 0.90 kGy) or medium doses (1.8 to 2.0 kGy), and each dose was delivered at either a low (2.5 M/min conveyor speed) or high (5.4 M/min) dose rate. Low-dose irradiation reduced L. monocytogenes by more than 2 log and S. typhimurium by 1 to 3 log. Pathogen populations and total plate counts (TPC) were reduced to undetectable levels by medium doses. No meat quality attributes were affected, and no dose rate effect was observed. Nitrite reduced (P 0.05) both pathogens and TPC during 7 degrees C storage in ham, especially when combined with low-dose irradiation

Data driven transmission power control for wireless sensor networks

NARCIS (Netherlands)

kotian, Roshan; Exarchakos, Georgios; Liotta, Antonio; Di Fatta, G.; Fortino, G.; Li, W.; Pathan, M.; Stahl, F.; Guerrieri, A.

2015-01-01

Transmission Power Control (TPC) is employed in the sensor nodes with the main objective of minimizing transmission power consumption. However, major drawbacks with well-known TPC are time consuming and energy inefficient initialization phase. Moreover, they employ Received Signal Strength Indicator

'Knowledge for better health' revisited - the increasing significance of health research systems: a review by departing Editors-in-Chief.

Science.gov (United States)

Hanney, Stephen R; González-Block, Miguel A

2017-10-02

How can nations organise research investments to obtain the best bundle of knowledge and the maximum level of improved health, spread as equitably as possible? This question was the central focus of a major initiative from WHO led by Prof Tikki Pang, which resulted in a range of developments, including the publication of a conceptual framework for national health research systems - Knowledge for better health - in 2003, and in the founding of the journal Health Research Policy and Systems (HARPS). As Editors-in-Chief of the journal since 2006, we mark our retirement by tracking both the progress of the journal and the development of national health research systems. HARPS has maintained its focus on a range of central themes that are key components of a national health research system in any country. These include building capacity to conduct and use health research, identifying appropriate priorities, securing funds and allocating them accountably, producing scientifically valid research outputs, promoting the use of research in polices and practice in order to improve health, and monitoring and evaluating the health research system. Some of the themes covered in HARPS are now receiving increased attention and, for example, with the assessment of research impact and development of knowledge translation platforms, the journal has covered their progress throughout that expansion of interest. In addition, there is increasing recognition of new imperatives, including the importance of promoting gender equality in health research if benefits are to be maximised. In this Editorial, we outline some of the diverse and developing perspectives considered within each theme, as well as considering how they are held together by the growing desire to build effective health research systems in all countries.From 2003 until mid-June 2017, HARPS published 590 articles on the above and related themes, with authors being located in 76 countries. We present quantitative data tracing

Validation of in vivo 2D displacements from spiral cine DENSE at 3T.

Science.gov (United States)

Wehner, Gregory J; Suever, Jonathan D; Haggerty, Christopher M; Jing, Linyuan; Powell, David K; Hamlet, Sean M; Grabau, Jonathan D; Mojsejenko, Walter Dimitri; Zhong, Xiaodong; Epstein, Frederick H; Fornwalt, Brandon K

2015-01-30

Displacement Encoding with Stimulated Echoes (DENSE) encodes displacement into the phase of the magnetic resonance signal. Due to the stimulated echo, the signal is inherently low and fades through the cardiac cycle. To compensate, a spiral acquisition has been used at 1.5T. This spiral sequence has not been validated at 3T, where the increased signal would be valuable, but field inhomogeneities may result in measurement errors. We hypothesized that spiral cine DENSE is valid at 3T and tested this hypothesis by measuring displacement errors at both 1.5T and 3T in vivo. Two-dimensional spiral cine DENSE and tagged imaging of the left ventricle were performed on ten healthy subjects at 3T and six healthy subjects at 1.5T. Intersection points were identified on tagged images near end-systole. Displacements from the DENSE images were used to project those points back to their origins. The deviation from a perfect grid was used as a measure of accuracy and quantified as root-mean-squared error. This measure was compared between 3T and 1.5T with the Wilcoxon rank sum test. Inter-observer variability of strains and torsion quantified by DENSE and agreement between DENSE and harmonic phase (HARP) were assessed by Bland-Altman analyses. The signal to noise ratio (SNR) at each cardiac phase was compared between 3T and 1.5T with the Wilcoxon rank sum test. The displacement accuracy of spiral cine DENSE was not different between 3T and 1.5T (1.2 ± 0.3 mm and 1.2 ± 0.4 mm, respectively). Both values were lower than the DENSE pixel spacing of 2.8 mm. There were no substantial differences in inter-observer variability of DENSE or agreement of DENSE and HARP between 3T and 1.5T. Relative to 1.5T, the SNR at 3T was greater by a factor of 1.4 ± 0.3. The spiral cine DENSE acquisition that has been used at 1.5T to measure cardiac displacements can be applied at 3T with equivalent accuracy. The inter-observer variability and agreement of DENSE-derived peak strains and

Stationary spiraling eddies in presence of polar amplification of global warming as a governing factor of ecology of Greenland seals White Sea population: results of verification study

Science.gov (United States)

Melentyev, K.; Chernook, V.; Melentyev, V.

2003-04-01

Ice-associated forms of marine mammals are representatives of a high level of fodder chains in the ocean and taxation of population number for different group, as assessment of ecology and animal welfare are the important tasks for marine biology, ecology, fishery and other application uses. Many problems create a global warming and antropogenical impact on marine and coastal ecosystem. In order to investigate ice covered Arctic Ocean and charting the number of seals were performed annual inspections onboard research aircraft PINRO "Arktika". Multi-spectral airborne and satellite observations were fulfilled regularly from Barents and White Sea to the Bering and Okhotsk Sea (1996-2002). A contemporary status of different group of sea mammals was evaluated, where number of adults and pups were checked separately. In situ observations were provided with using helicopter and icebreaker for gathering a water samples and ice cores (with following biochemical and toxicological analysis). A prevailing part of life cycle of Greenland seals (harp seal) is strongly depended from winter hydrology (water masses, stable currents, meandering fronts, stationary eddies) and closely connected with type of ice (pack, fast ice) and other parameters of ice (age, origin, salinity, ice edge.). First-year ice floes which has a specific properties and distinctive features are used by harp seals for pupping, lactation, molting, pairing and resting. Ringed seals, inversely, use for corresponding purposes only fast-ice. Different aspects of ecology, and migration features of harp seals were analyzed in frame of verification study. It was revealed a scale of influence of winter severity and wind regime, but stationary eddies in the White Sea is most effective governing factor (novelty). Following relationship " eddies - ecology of Greenland seal White Sea population " will be discussed: A) regularities of eddies formation and their spatial arrangement, temporal (seasonal and annual

Study of bifurcation behavior of two-dimensional turbo product code decoders

Energy Technology Data Exchange (ETDEWEB)

He Yejun [Department of Electronic and Information Engineering, Hong Kong Polytechnic University, Hunghom, Hong Kong (China); Lau, Francis C.M. [Department of Electronic and Information Engineering, Hong Kong Polytechnic University, Hunghom, Hong Kong (China)], E-mail: encmlau@polyu.edu.hk; Tse, Chi K. [Department of Electronic and Information Engineering, Hong Kong Polytechnic University, Hunghom, Hong Kong (China)

2008-04-15

Turbo codes, low-density parity-check (LDPC) codes and turbo product codes (TPCs) are high performance error-correction codes which employ iterative algorithms for decoding. Under different conditions, the behaviors of the decoders are different. While the nonlinear dynamical behaviors of turbo code decoders and LDPC decoders have been reported in the literature, the dynamical behavior of TPC decoders is relatively unexplored. In this paper, we investigate the behavior of the iterative algorithm of a two-dimensional TPC decoder when the input signal-to-noise ratio (SNR) varies. The quantity to be measured is the mean square value of the posterior probabilities of the information bits. Unlike turbo decoders or LDPC decoders, TPC decoders do not produce a clear 'waterfall region'. This is mainly because the TPC decoding algorithm does not converge to 'indecisive' fixed points even at very low SNR values.

Antioxidant and cytoprotective activities of Piper betle, Areca catechu, Uncaria gambir and betel quid with and without calcium hydroxide.

Science.gov (United States)

Sazwi, Nordin Nur; Nalina, Thurairajah; Abdul Rahim, Zubaidah Haji

2013-12-11

Betel quid chewing is a popular habit in Southeast Asia. It is believed that chewing betel quid could reduce stress, strengthen teeth and maintain oral hygiene. The aim of this study was to investigate the antioxidant and cytoprotective activities of each of the ingredients of betel quid and compared with betel quid itself (with and without calcium hydroxide). The correlation of their cytoprotective and antioxidant activities with phenolic content was also determined. Five samples (betel leaf, areca nut, gambir, betel quid and betel quid containing calcium hydroxide) were extracted in deionized distilled water for 12 hours at 37°C. Antioxidant activities were evaluated for radical scavenging activity using DPPH assay, ferric reducing activity using FRAP assay and lipid peroxidation inhibition activity using FTC assay. Total phenolic content (TPC) was determined using Folin-Ciocalteu procedure. Phenolic composition was analyzed using LC-MS/MS. Cytoprotective activity towards human gingival fibroblast cells was examined using MTT assay. Among the ingredients of betel quid, gambir demonstrated the highest antioxidant (DPPH - IC50 = 6.4 ± 0.8 μg/mL, FRAP - 5717.8 ± 537.6 μmol Fe(II)/mg), total phenolic content (TPC - 1142.5 ± 106.8 μg TAE/mg) and cytoprotective (100.1 ± 4.6%) activities. Betel quid when compared with betel quid containing calcium hydroxide has higher antioxidant (DPPH - IC50 =59.4 ± 4.4 μg/mL, FRAP - 1022.2 ± 235.7 μmol Fe(II)/mg), total phenolic content (TPC - 140.0 ± 22.3 μg TAE/mg), and cytoprotective (113.5 ± 15.9%) activities. However, all of the five samples showed good lipid peroxidation inhibition compared to vitamin E. LC-MS/MS analysis revealed the presence of quinic acid as the major compound of gambir and betel quid. A positive correlation was observed between TPC and radical scavenging (r = 0.972), reducing power (r = 0.981) and cytoprotective activity (r = 0.682). The betel quid has higher TPC, and antioxidant and

Total Content of Phenolics and Antioxidant Activity in Crispbreads with Plant By-product addition

Directory of Open Access Journals (Sweden)

Konrade Daiga

2017-11-01

Full Text Available Vegetable processing in food industry results in significant amount of by-products – peel, mark, bark, seeds still rich in bioactive compounds. Apple, carrot and pumpkin peel and mark may be used for production of crispbreads as functional ingredients. The objective of this study is to investigate the stability of total phenolic content (TPC and antioxidant activity after high temperature and short time (HTST extrusion cooking of a wheat and rice-based crispbreads with addition of apple, carrot and pumpkin by-products obtained after juice extraxtion and dried. Raw materials for crispbread production were wheat flour, rice flour, wheat bran (72%, 24% and 4% respectively with addition of microwave–vacuum dried by-product powder in different amount (5%, 10%, 15%, 20%. Extrusion process was performed by using a laboratory singlescrew extruder GÖTTFERT 1 screw Extrusiometer L series (Germany. Total phenolic content (TPC was determined using the Folin Ciocalteu method. Antioxidant activity was evaluated by free radical 2, 2-diphenyl-1-picrylhydrazyl (DPPH antioxidant scavenging activity using a modified colorimetric method. Comparing different raw formulations, it was observed that the TPC of the apple by-product flour was significantly higher (p < 0.05 than in carrot and pumpkin flour. TPC in cereal-based crispbread was 36.06±1.15 before extrusion and 13.90±1.01 mg GAEg-1 DW (milligram Gallic acid equivalent per 100 g of dry weight (mg GAE 100 g−1 DW after extrusion. Addition of apple BPF increased TPC in crispbreads to 106.25±2.08, carrot BPF 84.73±3.45 and pumpkin BPF to 108.82±1.04 mg GAEg−1 DW. Antioxidant activity of control sample was 1.07±0.01mg TE (Trolox equivalents g−1 DW but in samples with addition of 20% apple by-products, it reached 3.77±0.02 TE g−1 DW for samples wih 20% carrot by-products reached 2.52±0.03TE g−1 DW and for samples wih 20% pumpkin by-products reached 3.77±0.02 TE g−1 DW.

A change in fault-plane orientation between foreshocks and aftershocks of the Galway Lake earthquake, ML = 5.2, 1975, Mojave desert, California

Science.gov (United States)

Fuis, G.S.; Lindh, A.G.

1979-01-01

A marked change is observed in P/SV amplitude ratios, measured at station TPC, from foreshocks to aftershocks of the Galway Lake earthquake. This change is interpreted to be the result of a change in fault-plane orientation occurring between foreshocks and aftershocks. The Galway Lake earthquake, ML= 5.2, occurred on June 1, 1975. The first-motion fault-plane solutions for the main shock and most foreshocks and aftershocks indicate chiefly right-lateral strike-slip on NNW-striking planes that dip steeply, 70-90??, to the WSW. The main event was preceded by nine located foreshocks, ranging in magnitude from 1.9 to 3.4, over a period of 12 weeks, starting on March 9, 1975. All of the foreshocks form a tight cluster approximately 1 km in diameter. This cluster includes the main shock. Aftershocks are distributed over a 6-km-long fault zone, but only those that occurred inside the foreshock cluster are used in this study. Seismograms recorded at TPC (?? = 61 km), PEC (?? = 93 km), and CSP (?? = 83 km) are the data used here. The seismograms recorded at TPC show very consistent P/SV amplitude ratios for foreshocks. For aftershocks the P/SV ratios are scattered, but generally quite different from foreshock ratios. Most of the scatter for the aftershocks is confined to the two days following the main shock. Thereafter, however, the P/SV ratios are consistently half as large as for foreshocks. More subtle (and questionable) changes in the P/SV ratios are observed at PEC and CSP. Using theoretical P/SV amplitude ratios, one can reproduce the observations at TPC, PEC and CSP by invoking a 5-12?? counterclockwise change in fault strike between foreshocks and aftershocks. This interpretation is not unique, but it fits the data better than invoking, for example, changes in dip or slip angle. First-motion data cannot resolve this small change, but they permit it. Attenuation changes would appear to be ruled out by the fact that changes in the amplitude ratios, PTPC/PPEC and ptpc

Changes in total phenol, flavonoid contents and anti-Lactobacillus activity of Callisia fragrans due to extraction solvent

Science.gov (United States)

Le, Thom; Cao, Diem Kieu; Pham, Thanh Vy; Huynh, Tan Dat; Ta, Nhat Thuy Anh; Nguyen, Ngoc Thao Linh; Nguyen, Huu Thanh; Le, Hue Huong; Bui, Anh Vo; Truong, Dieu-Hien

2018-04-01

Callisia fragrans is a wonder herb with many medicinal properties such as burn, dental diseases, cancer diseases and arthritis in folk medicine. It is noted that the phytochemical constituents and antimicrobial activity of traditional plants depend on not only the extracting method but also the solvent used for extraction. In this study, the effect of five extraction solvents (i.e., distilled water, 80% methanol, 80% ethanol, 80% ethyl acetate, and 80% chloroform) on yield, total phenolic content (TPC) and total flavonoid content (TFC) of Callisia leaves was determined. Besides, changes in anti-Lactobacillus fermentum activity of C. fragrans freeze-dried extract was also evaluated using disk-diffusion method. The recovery percentage of extractable yield of fresh leaves are ranged from 11.93% w/w for distilled water extract to 16.60% w/w for aqueous ethanol extracts. The yield of 80% aqueous methanol extract (16.27% w/w) is only slightly less than that of the ethanol extract. Significant differences were observed among TPC and TFC obtaining by 80% methanol (0.0522% and 0.0335% w/w, respectively) compared to other solvents (p < 0.05). TPC and TFC of C. fragrans extracts increase in the following order: distilled water < 80% chloroform < 80% ethyl acetate < 80% ethanol < 80% methanol. The results revealed that 80% aqueous methanol Calissia extracts has moderate inhibition (9.0 mm of inhibition zone for 1.5 mg/mL of extracts) of L. fermentum compared to standard antibacterial agent. Based on the study results, it can be concluded that the yield, TPC and TFC of C. frgrans extract varied with the extracting solvent. It also showed that Callisia extracts can prevent dental caries by inhibiting the growth of L. fermentum, towards new insights for treatment of dental caries.

Effect of contaminant concentration on in situ bacterial sulfate reduction and methanogenesis in phenol-contaminated groundwater

International Nuclear Information System (INIS)

Baker, Kieran M.; Bottrell, Simon H.; Thornton, Steven F.; Peel, Kate E.; Spence, Michael J.

2012-01-01

The availability of dissolved O 2 can limit biodegradation of organic compounds in aquifers. Where O 2 is depleted, biodegradation proceeds via anaerobic processes, including NO 3 -, Mn(IV)-, Fe(III)- and SO 4 -reduction and fermentation/methanogenesis. The environmental controls on these anaerobic processes must be understood to support implementation of management strategies such as monitored natural attenuation (MNA). In this study stable isotope analysis is used to show that the relative significance of two key anaerobic biodegradation processes (bacterial SO 4 reduction (BSR) and methanogenesis) in a phenol-contaminated sandstone aquifer is sensitive to spatial and temporal changes in total dissolved phenols concentration (TPC) (= phenol + cresols + dimethylphenols) over a 5-a period. In general, 34 SO 4 -enrichment (characteristic of bacterial SO 4 reduction) is restricted spatially to locations where TPC −1 . In contrast, 13 C-depleted CH 4 and 13 C-enriched CO 2 isotope compositions (characteristic of methanogenesis) were measured at TPC up to 8000 mg L −1 . This is consistent with previous studies that demonstrate suppression of BSR at TPC of >500 mg L −1 , and suggests that methanogenic microorganisms may have a higher tolerance for TPC in this contaminant plume. It is concluded that isotopic enrichment trends can be used to identify conditions under which in situ biodegradation may be limited by the properties of the biodegradation substrate (in this case TPC). Such data may be used to deduce the performance of MNA for contaminated groundwater in similar settings.

Main Injector Particle Production Experiment Status

International Nuclear Information System (INIS)

Lebedev, Andre

2007-01-01

MIPP (FNAL-E907) is a large acceptance spectrometer to measure hadronic particle production - TPC and wire chambers to measure track parameters - TPC dE/dx, ToF, differential Cherenkov and ring imaging Cherenkov give π/K/p separation up to 100 GeV/c

Straightforward synthesis of a triazine-based porous carbon with high gas-uptake capacities

DEFF Research Database (Denmark)

Hu, Xinming; Chen, Qi; Zhao, Yan Chao

2014-01-01

A triazine-based porous carbon material (TPC-1) was prepared directly from a fluorinated aromatic nitrile in molten zinc chloride. Trimerization of the nitrile and subsequent defluorination carbonization of the polymeric network result in the formation of TPC-1. The defluorination process is reve...

Experimental characterisation of recycled (glass/tpu woven fabric) flake reinforced thermoplastic composites

NARCIS (Netherlands)

Abdul Rasheed, Mohammed Iqbal; Rietman, Bert; Visser, Roy; Akkerman, Remko; Hoa, S.V.; Hubert, P.

2013-01-01

Recycling of continuously reinforced thermoplastic composites (TPC) has a substantial prospect at present and in future due to its increasing availability and rapidly growing application regime. This study focusses on the first steps in using TPC process scrap on a scale in which its maximum

Measurement of magnetic and electric field inhomogenities in a time projection chamber using laser tracks

International Nuclear Information System (INIS)

Benetta, M.; Froberger, J.P.; Lehraus, I.; Mathewson, R.; May, J.; Price, M.; Schlater, D.; Tejessi, W.; Witzeling, W.

1985-01-01

The large time projection chambers (TPC) for particle track measurements have their electric drift field parallel to the magnetic field which is needed for the momentum measurement of the particles. Small field inhomogeneities of the order of epsilon times the main field cause large track distortions (coordinate displacements) of the order of epsilon times the driftlength. It is therefore important for every TPC to know the inhomogeneities very well. Laser rays have proven to be useful to study them. We report here on our experience with a TPC having a maximum drift length of 1.3 m

A time projection chamber with GEM-based readout

Energy Technology Data Exchange (ETDEWEB)

Attié, David [CEA Saclay, IRFU, F-91191 Gif-sur-Yvette (France); Behnke, Ties [Deutsches Elektronen-Synchrotron DESY, A Research Centre of the Helmholtz Association, Notkestrasse 85, 22607 Hamburg (Hamburg site) (Germany); Bellerive, Alain [Carleton University, Department of Physics, 1125 Colonel By Drive, Ottawa, ON, Canada K1S 5B6 (Canada); Bezshyyko, Oleg [Taras Shevchenko National University of Kyiv, 64/13, Volodymyrska Street, City of Kyiv 01601 (Ukraine); Bhattacharya, Deb Sankar [CEA Saclay, IRFU, F-91191 Gif-sur-Yvette (France); now at Saha Institute of Nuclear Physics, 1/AF, Sector 1, Bidhan Nagar, Kolkata 700064 (India); Bhattacharya, Purba [Saha Institute of Nuclear Physics, 1/AF, Sector 1, Bidhan Nagar, Kolkata 700064 (India); now at National Institute of Science Education and Research (NISER) Bhubaneswar, P.O. Jatni, Khurda 752050, Odisha (India); Bhattacharya, Sudeb [Saha Institute of Nuclear Physics, 1/AF, Sector 1, Bidhan Nagar, Kolkata 700064 (India); Caiazza, Stefano [Deutsches Elektronen-Synchrotron DESY, A Research Centre of the Helmholtz Association, Notkestrasse 85, 22607 Hamburg (Hamburg site) (Germany); now at Johannes Gutenberg Universität Mainz, Institut für Physik, 55099 Mainz (Germany); Colas, Paul [CEA Saclay, IRFU, F-91191 Gif-sur-Yvette (France); Lentdecker, Gilles De [Inter University ULB-VUB, Av. Fr. Roosevelt 50, B1050 Bruxelles (Belgium); Dehmelt, Klaus [Deutsches Elektronen-Synchrotron DESY, A Research Centre of the Helmholtz Association, Notkestrasse 85, 22607 Hamburg (Hamburg site) (Germany); now at State University of New York at Stony Brook, Department of Physics and Astronomy, Stony Brook, NY 11794-3800 (United States); Desch, Klaus [Universität Bonn, Physikalisches Institut, Nußallee 12, 53115 Bonn (Germany); and others

2017-06-01

For the International Large Detector concept at the planned International Linear Collider, the use of time projection chambers (TPC) with micro-pattern gas detector readout as the main tracking detector is investigated. In this paper, results from a prototype TPC, placed in a 1 T solenoidal field and read out with three independent Gas Electron Multiplier (GEM) based readout modules, are reported. The TPC was exposed to a 6 GeV electron beam at the DESY II synchrotron. The efficiency for reconstructing hits, the measurement of the drift velocity, the space point resolution and the control of field inhomogeneities are presented.

Development of time projection chamber for precise neutron lifetime measurement using pulsed cold neutron beams

Energy Technology Data Exchange (ETDEWEB)

Arimoto, Y. [High Energy Accelerator Research Organization, Ibaraki (Japan); Higashi, N. [Graduate School of Science, University of Tokyo, Tokyo (Japan); Igarashi, Y. [High Energy Accelerator Research Organization, Ibaraki (Japan); Iwashita, Y. [Institute for Chemical Research, Kyoto University, Kyoto (Japan); Ino, T. [High Energy Accelerator Research Organization, Ibaraki (Japan); Katayama, R. [Graduate School of Science, University of Tokyo, Tokyo (Japan); Kitaguchi, M. [Kobayashi-Maskawa Institute, Nagoya University, Aichi (Japan); Kitahara, R. [Graduate School of Science, Kyoto University, Kyoto (Japan); Matsumura, H.; Mishima, K. [High Energy Accelerator Research Organization, Ibaraki (Japan); Nagakura, N.; Oide, H. [Graduate School of Science, University of Tokyo, Tokyo (Japan); Otono, H., E-mail: otono@phys.kyushu-u.ac.jp [Research Centre for Advanced Particle Physics, Kyushu University, Fukuoka (Japan); Sakakibara, R. [Department of Physics, Nagoya University, Aichi (Japan); Shima, T. [Research Center for Nuclear Physics, Osaka University, Osaka (Japan); Shimizu, H.M.; Sugino, T. [Department of Physics, Nagoya University, Aichi (Japan); Sumi, N. [Faculty of Sciences, Kyushu University, Fukuoka (Japan); Sumino, H. [Department of Basic Science, University of Tokyo, Tokyo (Japan); Taketani, K. [High Energy Accelerator Research Organization, Ibaraki (Japan); and others

2015-11-01

A new time projection chamber (TPC) was developed for neutron lifetime measurement using a pulsed cold neutron spallation source at the Japan Proton Accelerator Research Complex (J-PARC). Managing considerable background events from natural sources and the beam radioactivity is a challenging aspect of this measurement. To overcome this problem, the developed TPC has unprecedented features such as the use of polyether-ether-ketone plates in the support structure and internal surfaces covered with {sup 6}Li-enriched tiles to absorb outlier neutrons. In this paper, the design and performance of the new TPC are reported in detail.

Effect of water cooking on antioxidant capacity of carotenoid-rich vegetables in Taiwan

Directory of Open Access Journals (Sweden)

Fuh-Juin Kao

2014-06-01

Full Text Available Carotenoid-rich green leafy vegetables including cilantro, Thai basil leaves, sweet potato leaves, and choy sum were selected to evaluate the effects of water cooking or boiling on their total carotenoid content (TCC, total phenolic content (TPC, and total antioxidant capacity (TAC. The percentage inhibition of peroxidation (%IP, Trolox equivalent antioxidant capacity (TEAC, and metal-chelating effect were used to evaluate TAC. The results indicated that TCC reached the maximum after boiling cilantro, Thai basil leaves, and sweet potato leaves for 10 minutes, 5 minutes, and 5 minutes, respectively, and choy sum remained almost unchanged after 30 minutes of boiling. Boiling cilantro and choy sum had a negative effect on their TPC, whereas there was a significant increase in TPC of Thai basil leaf and sweet potato leaf at 1 minute and 5 minutes of boiling, respectively. During water cooking, TAC of the vegetables did not demonstrate a consistent trend. However, TCC was a vital contributor to %IP, whereas TPC showed a strong association with TEAC. Our findings suggest that a boiling time of ≤5 minutes would be better for preserving or enhancing TCC and TPC as well as revealing a higher %IP, TEAC, or metal-chelating effect for the four vegetables investigated in this study.

Optimization of extraction of phenolic content from conyza bonariensis

International Nuclear Information System (INIS)

Thabit, R.A.S.; Cheng, X.R.

2014-01-01

This study aims to find out the effects of solvent type (ethanol, water, and ionic liquid (1-butyl-3-methylimidazolium bromide)(BMIM)Br), time (30-90min), and microwave power (200 - 600w) on extraction rate, antioxidant activity, and total phenolic content (TPC) of Conyza bonariensis. The functional components from C. bonariensis were extracted using high efficient microwave-assisted extraction technology. The experiments were carried out according to 17 runs with 3 variables and three levels for the optimization in response surface methodology (RSM) system. The extracts were analyzed by spectrophotometeric methods for the antioxidant and TPC. The optimal conditions for extraction rate, antioxidant and TPC were determined by RSM. The Box Behnken design (BBD) showed the polynomial. The optimal conditions, including (BMIM)Br as the solvent with 45.47 min and 300.60 w power, lead to the best extraction rate (25.94%), maximum DPPH radical scavenging (95.90%) and maximum TPC (174.18 mg GAE/g). Under these conditions, the experimental extraction rate was 25.13 ± 0.85 %, DPPH radical scavenging was 93.8 ± 1.67% and TPC was 171.5 ± 1.06mg GAE/g of the C. bonariensis extract, which matched with the predicted values. (author)

ICARUS+NESSiE: A proposal for short baseline neutrino anomalies with innovative LAr imaging detectors coupled with large muon spectrometers

Science.gov (United States)

Gibin, D.

2013-04-01

The proposal for an experimental search for sterile neutrinos beyond the Standard Model with a new CERN-SPS neutrino beam is presented. The experiment is based on two identical LAr-TPC's followed by magnetized spectrometers, observing the electron and muon neutrino events at 1600 and 300 m from the proton target. This project will exploit the ICARUS T600, moved from LNGS to the CERN "Far" position. An additional 1/4 of the T600 detector will be constructed and located in the "Near" position. Two spectrometers will be placed downstream of the two LAr-TPC detectors to greatly complement the physics capabilities. Comparing the two detectors, in absence of oscillations, all cross sections and experimental biases cancel out. Any difference of the event distributions at the locations of the two detectors might be attributed to the possible existence of ν-oscillations, presumably due to additional neutrinos with a mixing angle sin2(2θ) and a larger mass difference Δmnew2. The superior quality of the LAr imaging TPC, in particular its unique electron-π0 discrimination allows full rejection of backgrounds and offers a lossless νe detection capability. The determination of the muon charge with the spectrometers allows the full separation of νμ from anti-νμ and therefore controlling systematics from muon mis-identification largely at high momenta.

Effect of five year storage on total phenolic content and antioxidant capacity of almond (Amygdalus communisL.) hull and shell from different genotypes.

Science.gov (United States)

Moosavi Dolatabadi, Khadijeh Sadat; Dehghan, Gholamreza; Hosseini, Siavash; Jahanban Esfahlan, Ali

2015-01-01

Almond (Prunus amygdalus) hull and shell are agricultural by-products that are a source of phenolic compounds.The processing of almond produce shell and hull, accounts for more than 50% by dry weight of the almond fruits. Recently, more studies have focused on the influence of storage conditions and postharvest handling on the nutritional quality of fruits, especially the antioxidant phenolics. In this study, influence of long-term storage (five years) on the total phenolic and antioxidant capacity of almond hull and shell from different genotypes was evaluated. The fruits of subjected genotypes were collected and their hull and shell were separated. They were dried and reduced to fine powder. This powder stored at room temperature for five years. The total phenolic content (TPC) and bioactivities (antioxidant potential: DPPH and ABTS radical scavenging and reducing power) of extracts were evaluated using spectrophotometric methods. It was found that TPC content and bioactivity levels in the stored almond hull and shell were different, compared to the hulls and shells which were evaluated in 2007. S1-4 genotype had the highest TPC and reducing power in its hull and shell.Low correlation coefficient was observed between phenolic content and the DPPH radical scavenging percentage in hull and shell extract. For the first time, results of this investigation showed that storage can influence the antioxidant and antiradical potential of almond hull and shell.

Phenolic acids, anthocyanins, and antioxidant capacity in rice (Oryza sativa L.) grains at four stages of development after flowering.

Science.gov (United States)

Shao, Yafang; Xu, Feifei; Sun, Xiao; Bao, Jinsong; Beta, Trust

2014-01-15

This study investigated differences in total phenolic content (TPC), antioxidant capacity, and phenolic acids in free, conjugated and bound fractions of white (unpolished), red and black rice at 1-, 2-, and 3-weeks of grain development after flowering and at maturity. Unlike the TPC (mg/100g) of white rice (14.6-33.4) and red rice (66.8-422.2) which was significantly higher at 1-week than at later stages, the TPC of black rice (56.5-82.0) was highest at maturity. The antioxidant capacity measured by DPPH radical scavenging and ORAC methods generally followed a similar trend as TPC. Only black rice had detectable anthocyanins (26.5-174.7mg/100g). Cyanidin-3-glucoside (C3G) and peonidin-3-glucoside (P3G) were the main anthocyanins in black rice showing significantly higher levels at 2- and 3-weeks than at 1-week development and at maturity. At all stages, the phenolic acids existed mainly in the bound form as detected by HPLC and confirmed by LC-MS/MS. Black rice (20.1-31.7mg/100g) had higher total bound phenolic acids than white rice and red rice (7.0-11.8mg/100g). Protocatechuic acid was detected in red rice and black rice with relatively high levels at 1-week development (1.41mg/100g) and at maturity (4.48mg/100g), respectively. Vanillic acid (2.4-5.4mg/100g) was detected only in black rice where it peaked at maturity. p-Coumaric acid (black rice. Ferulic acid (4.0-17.9mg/100g), the most abundant bound phenolic acid, had an inconsistent trend with higher levels being observed in black rice where it peaked at maturity. Isoferulic acid levels (0.8-1.6mg/100g) were generally low with slightly elevated values being observed at maturity. Overall black rice had higher total bound phenolic acids than white and red rice while white rice at all stages of development after flowering. Copyright © 2013 Elsevier Ltd. All rights reserved.

Antioxidant Activity and Bioactive Components of Oxalidaceae Fruit Extracts

International Nuclear Information System (INIS)

Asna, N.A.; Noriham, A.

2014-01-01

The study was conducted to evaluate the Antioxidant Activity (AA), Total Flavonoid Content (TFC), and Total Phenolic Content (TPC) of Oxalidaceae fruit extracts. Two types of Averrhoa carambola L. and two types of bilimbi fruits were used in this study. Bilimbi fruits selected were Averrhoa bilimbi L. and Averrhoa bilimbi cv. while Averrhoa carambola L. selected were Averrhoa carambola L. (honey type) and another type of Averrhoa carambola L. which is known as tart type. The maturity stage for both Averrhoa carambola L. fruits (honey and tart type) were selected at commercial maturity stages which were stage 3 and stage 4. Antioxidant estimation of oxalidaceae fruit extracts were evaluated by using Total Flavonoid Content (TFC) and Total Phenolic Content (TPC), while antioxidant activity were evaluated using scavenging of 2,2-diphenyl-1-picrylhydrazyl radical (DPPH), β-carotene Bleaching (BCB) and Ferric Reducing Antioxidant Power (FRAP) assays. Phytochemical screening of alkaloids, flavonoids, terpenoids, steroids, tannins and saponins were also performed on all samples. Averrhoa carambola L. indicated positive results for all phytochemical screening conducted and similar results were observed from bilimbi fruits, except for alkaloids. Averrhoa carambola L. (tart type) of stage 4 possessed higher TPC and TFC followed by Averrhoa carambola L. (honey type) of stage 4. Averrhoa carambola L. (tart type) of stage 4 also exhibited high scavenging effect (74 %) as determined by DPPH assay with the value of EC 50 72.36 mg/ ml while Averrhoa carambola L. (honey type) of stage 3 showed significantly lower percentage of scavenging effect. The results also demonstrated that FRAP values of Averrhoa carambola L. (honey type) of stage 4 and Averrhoa carambola L. (tart type) of stage 4 were higher than other samples (5.1023 mmol TE/ g and 5.0759 mmol TE/ g) and similar trends were observed for β-carotene Bleaching (BCB) assay, where Averrhoa carambola L. (honey type) of stage 4

Usefulness of tenderness to characterise fibromyalgia severity in women.

Science.gov (United States)

Aparicio, V A; Carbonell-Baeza, A; Ortega, F B; Estevez, F; Ruiz, J R; Delgado-Fernández, M

2011-01-01

To investigate the usefulness of tenderness (tender points count (TPC) and algometer score) to characterise fibromyalgia (FM) severity and symptomatology in women. The study sample comprised 174 women aged 51±7 years. We ossesse tenderness using pressure algometry; quality of life by means of the Short-Form 36 Health Survey (SF-36) and the Hospital Anxiety and Depression Scale (HADS). We used the FM impact questionnaire (FIQ) to assess FM severity and symptomatology. Patients were categorised according to three FIQ-derived categories: FIQFIQFIQ≥59 (16.9±2 vs. 15.6±4, p=0.02), whereas no differences between groups were observed according to FIQ≥70 (17.0±2 vs. 16.2±3, p=0.12) or FM type (16.8±3 for type II vs. 15.9±4 for type I, p=0.13). We observed a significant association between TPC and FIQ-job difficulty, pain, morning tiredness and stiffness dimensions (all pFIQ, FIQ-anxiety, fatigue and depression dimensions (all p>0.05). Algometer score was lower in the FIQ≥70 (45.7±12 vs. 51.1±14, p=0.05) and FIQ≥59 (46.7±13 vs. 52.7±14, p=0.05) groups, and there were no difference between FM types (48.7±13 vs. 49.5±14 for type II and I respectively, p=0.81). Algometer score was not associated with total score of FIQ or FIQ dimensions (all p≥0.1). Widespread pain and pain hypersensitivity, as measured by TPC and algometer score, do not seem to be useful to characterise FM severity and symptomatology (measured by FIQ) in women.

Prototype for the ALEPH Time Projection Chamber

CERN Multimedia

1980-01-01

This is a prototype endplate piece constructed during R&D for the ALEPH Time Projection Chamber (TPC). ALEPH was one of 4 experiments at CERN's 27km Large Electron Positron collider (LEP) that ran from 1989 to 2000. ALEPH's TPC was a large-volume tracking chamber, 4.4 metres long and 3.6 metres in diameter - the largest TPC in existance at the time. This object is one of the endplates of a “Kind” sector, the smallest of the three types of sectors. The patterns etched into the copper form the cathode pads that measured particle track coordinates in the r-phi direction. It included a laser calibration system, a gating system to prevent space charge buildup, and a new radial pad geometry to improve resolution. the ALEPH TPC allowed for precise momentum measurements of the high-momentum particles from W and Z decays. The following institutes participated: CERN, Athens, Glasgow, Mainz, MPI Munich, INFN-Pisa, INFN-Trieste, Wisconsin.

SπRIT: A time-projection chamber for symmetry-energy studies

International Nuclear Information System (INIS)

Shane, R.; McIntosh, A.B.; Isobe, T.; Lynch, W.G.; Baba, H.; Barney, J.; Chajecki, Z.; Chartier, M.; Estee, J.; Famiano, M.; Hong, B.; Ieki, K.; Jhang, G.; Lemmon, R.; Lu, F.; Murakami, T.; Nakatsuka, N.; Nishimura, M.; Olsen, R.; Powell, W.

2015-01-01

A time-projection chamber (TPC) called the SAMURAI Pion-Reconstruction and Ion-Tracker (SπRIT) has recently been constructed at Michigan State University as part of an international effort to constrain the symmetry-energy term in the nuclear Equation of State (EoS). The SπRIT TPC will be used in conjunction with the SAMURAI spectrometer at the Radioactive Isotope Beam Factory (RIBF) at RIKEN to measure yield ratios for pions and other light isospin multiplets produced in central collisions of neutron-rich heavy ions, such as 132 Sn+ 124 Sn. The SπRIT TPC can function both as a TPC detector and as an active target. It has a vertical drift length of 50 cm, parallel to the magnetic field. Gas multiplication is achieved through the use of a multi-wire anode plane. Image charges, produced in the 12096 pads, are read out with the recently developed Generic Electronics for TPCs

A thiourea derivative as potential ionophore for copper sensing

Science.gov (United States)

Ying, Kook Shih; Heng, Lee Yook; Hassan, Nurul Izzaty; Hasbullah, Siti Aishah

2018-04-01

A new thiourea derivative, N1,N3-bis[[3,5-bis(trifluoromethyl)phenyl]carbamothioyl]isophthalamide (TPC), as a potential copper ionophore was investigated. TPC was immobilized via drop casting method into poly(n-butyl acrylate) pBA membrane and the sensor was characterized by potentiometric method. The sensor fabricated based on TPC showed a Nernstian response towards copper ion with the slope of 27.07±2.84 mV/decade in the range of 1.0×10-6 - 1.0-10-4 M and limit of detection of 6.24 × 10-7 M. In addition, based on the separate solution method (SSM), the logarithm selectivity coefficients were less than -3.00 for monovalent, divalent and trivalent cations that are present in the environmental water samples such as K+, Ca2+, Mg2+ and Fe3+. This confirmed that the sensor fabricated with TPC exhibited good sensitivity and selectivity towards copper ion.

A high-pressure hydrogen time projection chamber for the MuCap experiment

Energy Technology Data Exchange (ETDEWEB)

Egger, J.; Fahrni, D.; Hildebrandt, M.; Hofer, A.; Meier, L.; Petitjean, C. [Paul Scherrer Institute, Villigen PSI (Switzerland); Andreev, V.A.; Ganzha, V.A.; Kravtsov, P.A.; Krivshich, A.G.; Maev, E.M.; Maev, O.E.; Petrov, G.; Semenchuk, G.G.; Vasilyev, A.A.; Vorobyov, A.A.; Vznuzdaev, M.E. [Petersburg Nuclear Physics Institute, Gatchina (Russian Federation); Banks, T.I. [University of California, Department of Physics, Berkeley, California (United States); Clayton, S.M. [University of Illinois at Urbana-Champaign, Department of Physics, Urbana, Illinois (United States); Gray, F.E. [University of California, Department of Physics, Berkeley, California (United States); Regis University, Department of Physics and Computational Science, Denver, Colorado (United States); University of Washington, Department of Physics, Seattle, Washington (United States); Kammel, P.; Kiburg, B.; Winter, P. [University of Illinois at Urbana-Champaign, Department of Physics, Urbana, Illinois (United States); University of Washington, Department of Physics, Seattle, Washington (United States); Lauss, B. [Paul Scherrer Institute, Villigen PSI (Switzerland); University of California, Department of Physics, Berkeley, California (United States)

2014-10-15

The MuCap experiment at the Paul Scherrer Institute performed a high-precision measurement of the rate of the basic electroweak process of nuclear muon capture by the proton, μ{sup -} + p → n + ν{sub μ}. The experimental approach was based on the use of a time projection chamber (TPC) that operated in pure hydrogen gas at a pressure of 10bar and functioned as an active muon stopping target. The TPC detected the tracks of individual muon arrivals in three dimensions, while the trajectories of outgoing decay (Michel) electrons were measured by two surrounding wire chambers and a plastic scintillation hodoscope. The muon and electron detectors together enabled a precise measurement of the μp atom's lifetime, from which the nuclear muon capture rate was deduced. The TPC was also used to monitor the purity of the hydrogen gas by detecting the nuclear recoils that follow muon capture by elemental impurities. This paper describes the TPC design and performance in detail. (orig.)

ALICE presents its first award to Industry

CERN Multimedia

On 19 June, a French company received the first ALICE award to industry. ST Technologies has provided ALICE with a key device for the design of a very sophisticated chip for the readout of the ALICE Time Projection Chamber. Behind from left to right (Derrière de gauche à droite): Bernardo Mota, member of the ALTRO design team, Jurgen Schukraft, ALICE Spokesperson, Luciano Musa, leader of the ALTRO Design Team and Coordinator of the ALICE TPC FEE, Roberto Camapagnolo, member of the ALICE TPC FEE team, Jean-Pierre Coffin, Deputy of the ALICE Collaboration Board Chairman, Hans de Groot ALICE Resource Coordinator, Laurent Degoujon, ST - Data Converter Design Manager, Claude Engster, member of the ALICE TPC FEE team, Alain Delpi, ST - Data Converter Business Unit Manager, Carmen Gonzalez, member of the ALICE TPC FEE team, Yiota Foka, ALICE Outreach Coordinator; Front: Fabio Formenti , EP-ED Group Leader, Juan Antonio Rubio, ETT Division Leader The ALICE experiment is setting new demands on readout electronics i...

Irradiation of vegetables of the fourth sort: Radiosensitivity of E.Coli O157:H7 and effect on microbiological and sensory parameters

International Nuclear Information System (INIS)

Thumann Llermaly, Katherina Andrea

2004-01-01

Nowadays a wide variety of minimally processed or fourth sort vegetables are offered in Chile for direct consumption. The objectives of the present study were the determination of the natural microbiological contamination of two minimally processed mixed salads (Toscana and Four Seasons); the determination of the D 10 value for a Escherichia coli 0157:H7 strain in both salads; the evaluation of the effect of radiation with 5 D 10 doses on the initial microflora and the control of changes in the microbiological and sensory quality during a 7 days refrigerated storage. The natural microflora and changes of the microflora during the storage were evaluated assaying the total plate count (TPC), Enterobacteriaceae count (EC) and presence or absence of Escherichia coli 0157:H7 in 25 g. The effect on the sensory quality was evaluated through a triangular test at day 0 and day 7, in order to determine possible significantly differences between the no irradiated and the irradiated samples. A test for quality attributes was performed at 0, 3 and 7 days, to compare the irradiated salads with the no irradiated control. The levels of the initial microflora ranged for TPC between 10 6 cfu/g and 10 8 cfu/g in both Toscana and Four Seasons salads. The EC initial levels were between 10 4 cfu/g and 10 7 cfu/g in Toscana salad and 10 5 cfu/g and 10 7 cfu/g in Four Seasons salad. In both kind of salads no presence of Escherichia coli 0157:H7 in 25 g was detected. The D 10 value for the assayed strain was 0.09 kGy in both salads. Therefore, the 5 D 10 dose for the irradiation of the vegetables was 0.45 kGy. After irradiating with 0.45 kGy a 3 log reduction in TPC in both salads was observed. The EC was reduced in 2 log and 4 log in Toscana and Four Seasons salads, respectively. At the end of the refrigerated storage of the no irradiated samples the increase of the TPC was 2.8 and 1.6 log for Toscana and Four Seasons salads, respectively. A greater increase in the EC was observed

Web-based oil immersion whole slide imaging increases efficiency and clinical team satisfaction in hematopathology tumor board

Science.gov (United States)

Chen, Zhongchuan Will; Kohan, Jessica; Perkins, Sherrie L.; Hussong, Jerry W.; Salama, Mohamed E.

2014-01-01

Background: Whole slide imaging (WSI) is widely used for education and research, but is increasingly being used to streamline clinical workflow. We present our experience with regard to satisfaction and time utilization using oil immersion WSI for presentation of blood/marrow aspirate smears, core biopsies, and tissue sections in hematology/oncology tumor board/treatment planning conferences (TPC). Methods: Lymph nodes and bone marrow core biopsies were scanned at ×20 magnification and blood/marrow smears at 83X under oil immersion and uploaded to an online library with areas of interest to be displayed annotated digitally via web browser. Pathologist time required to prepare slides for scanning was compared to that required to prepare for microscope projection (MP). Time required to present cases during TPC was also compared. A 10-point evaluation survey was used to assess clinician satisfaction with each presentation method. Results: There was no significant difference in hematopathologist preparation time between WSI and MP. However, presentation time was significantly less for WSI compared to MP as selection and annotation of slides was done prior to TPC with WSI, enabling more efficient use of TPC presentation time. Survey results showed a significant increase in satisfaction by clinical attendees with regard to image quality, efficiency of presentation of pertinent findings, aid in clinical decision-making, and overall satisfaction regarding pathology presentation. A majority of respondents also noted decreased motion sickness with WSI. Conclusions: Whole slide imaging, particularly with the ability to use oil scanning, provides higher quality images compared to MP and significantly increases clinician satisfaction. WSI streamlines preparation for TPC by permitting prior slide selection, resulting in greater efficiency during TPC presentation. PMID:25379347

Web-based oil immersion whole slide imaging increases efficiency and clinical team satisfaction in hematopathology tumor board

Directory of Open Access Journals (Sweden)

Zhongchuan Will Chen

2014-01-01

Full Text Available Background: Whole slide imaging (WSI is widely used for education and research, but is increasingly being used to streamline clinical workflow. We present our experience with regard to satisfaction and time utilization using oil immersion WSI for presentation of blood/marrow aspirate smears, core biopsies, and tissue sections in hematology/oncology tumor board/treatment planning conferences (TPC. Methods: Lymph nodes and bone marrow core biopsies were scanned at ×20 magnification and blood/marrow smears at 83X under oil immersion and uploaded to an online library with areas of interest to be displayed annotated digitally via web browser. Pathologist time required to prepare slides for scanning was compared to that required to prepare for microscope projection (MP. Time required to present cases during TPC was also compared. A 10-point evaluation survey was used to assess clinician satisfaction with each presentation method. Results: There was no significant difference in hematopathologist preparation time between WSI and MP. However, presentation time was significantly less for WSI compared to MP as selection and annotation of slides was done prior to TPC with WSI, enabling more efficient use of TPC presentation time. Survey results showed a significant increase in satisfaction by clinical attendees with regard to image quality, efficiency of presentation of pertinent findings, aid in clinical decision-making, and overall satisfaction regarding pathology presentation. A majority of respondents also noted decreased motion sickness with WSI. Conclusions: Whole slide imaging, particularly with the ability to use oil scanning, provides higher quality images compared to MP and significantly increases clinician satisfaction. WSI streamlines preparation for TPC by permitting prior slide selection, resulting in greater efficiency during TPC presentation.

Quark fragmentation in e+e- collisions

International Nuclear Information System (INIS)

Oddone, P.

1984-12-01

This brief review of new results in quark and gluon fragmentation observed in e + e - collisions concentrates mostly on PEP results and, within PEP, mostly on TPC results. The new PETRA results have been reported at this conference by M. Davier. It is restricted to results on light quark fragmentation since the results on heavy quark fragmentation have been reported by J. Chapman

Total pleural covering technique for intractable pneumothorax in patient with Ehlers-Danlos syndrome.

Science.gov (United States)

Kadota, Yoshihisa; Fukui, Eriko; Kitahara, Naoto; Okura, Eiji; Ohta, Mitsunori

2016-07-01

We report a patient with vascular-type Ehlers-Danlos syndrome (vEDS) who developed pneumothorax and was treated with a total pleural covering technique (TPC). A 24-year-old man developed repeat pneumothorax with intermittent hemo-sputum. Based on unusual radiological manifestations of lung lesions and physical findings, EDS was suspected as an underlying cause of the pneumothorax. Surgical treatment was performed using a mediastinal fat pad and TPC, and no relapse was seen up to 2 years after surgery. TPC is a less invasive surgical approach for selected patients with vEDS. Accurate underlying diagnosis of vEDS and systemic evaluation of vascular complications are necessary before planning surgery.

New results on flavor production at PEP

International Nuclear Information System (INIS)

Barbaro-Galtieri, A.

1984-05-01

This report includes results from five PEP detectors: DELCO, HRS, MAC, MARK II and TPC. All, except the TPC, are presently taking data at PEP. The TPC is being upgraded: a new superconducting coil is being installed and other improvements are being implemented. The results discussed here are either new or improved since the Cornell Conference. New results on Particle Searches and a limit on neutrino generations are discussed. New data are included on weak couplings of c and b quarks. Various new results on hadron production are reported. All data were obtained in e +- collisions with total energy √s=29 GeV. 54 references

Hepatoprotective Activity of Methanolic Extract of Bauhinia purpurea Leaves against Paracetamol-Induced Hepatic Damage in Rats

Directory of Open Access Journals (Sweden)

F. Yahya

2013-01-01

Full Text Available In an attempt to further establish the pharmacological properties of Bauhinia purpurea (Fabaceae, hepatoprotective potential of methanol extract of B. purpurea leaves (MEBP was investigated using the paracetamol- (PCM- induced liver toxicity in rats. Five groups of rats (n=6 were used and administered orally once daily with 10% DMSO (negative control, 200 mg/kg silymarin (positive control, or MEBP (50, 250, and 500 mg/kg for 7 days, followed by the hepatotoxicity induction using paracetamol (PCM. The blood samples and livers were collected and subjected to biochemical and microscopical analysis. The extract was also subjected to antioxidant study using the 2, 2-diphenyl-1-picrylhydrazyl (DPPH radical scavenging assay with the total phenolic content (TPC also determined. From the histological observation, lymphocyte infiltration and marked necrosis were observed in PCM-treated groups (negative control, whereas maintenance of the normal hepatic structural was observed in group pretreated with silymarin and MEBP. Hepatotoxic rats pretreated with silymarin or MEBP exhibited significant decrease (P<0.05 in ALT and AST enzyme level. Moreover, the extract also exhibited antioxidant activity and contained high TPC. In conclusion, MEBP exerts potential hepatoprotective activity that could be partly attributed to its antioxidant activity and high phenolic content and thus warrants further investigation.

Radiosensitivity of Listeria innocua in fourth sort vegetables and effect of the irradiation on microbiological and sensory parameters

International Nuclear Information System (INIS)

Acevedo Gonzalez, Claudia Jose

2004-01-01

were between 10 4 cfu/g and 10 7 cfu/g in Toscana salad and 10 5 cfu/g and 10 8 cfu/g in Four Seasons salad. In both salads no presence of Listeria spp.in 25 g was detected. The D 10 values for the assayed strain were 0.19 kGy and 0.21 kGy for Toscana and Four Seasons salads, respectively. The 5 D 10 dose calculated, was 1.00 kGy, considering the mean of the D 10 values according to practical reasons. After irradiating Toscana salad with 1.00 kGy, reductions of 3.46 log and 3.5 log in the TPC and EC, respectively, were observed. The TPC and EC initially present in the Four Seasons salad were reduced in 3.5 log and 4.0, respectively, after the irradiation. No initial presence of Listeria spp.in 25 g was detected. At the end of the refrigerated storage of the no irradiated samples the increase of the TPC was 2.8 and 1.6 log for Toscana and Four Seasons salads, respectively. A greater increase in the EC was observed, reaching at day 7 values of 3.0 and 2.7 logs in Toscana and Four Seasons salads, respectively. In the irradiated samples, only slightly changes in the TPC and EC were observed. The results for the triangular test, showed no significantly differences at days 0 and 7, between the no irradiated and the irradiated salads. During the refrigerated storage, only in a some parameters significantly differences amongst days, were observed. The means of the results obtained for the Four Seasons salad, were similar to the central value (5.00) corresponding to the no irradiated control. According to the results of the study, irradiation is a feasible treatment for minimally processed mixed salads. When irradiating with 1.00 kGy, a reduction of the initial microflora without affecting the sensory quality, is obtained (au)

VizieR Online Data Catalog: Radial velocity curve of 51 Peg (Birkby+, 2017)

Science.gov (United States)

Birkby, J. L.; de Kok, R. J.; Brogi, M.; Schwarz, H.; Snellen, I. A. G.

2017-07-01

We observed the bright star 51 Peg (G2.5V, V=5.46mag, K=3.91mag) for 3.7hr during the night beginning 2010 October 21, using the CRyogenic InfraRed Echelle Spectrograph (CRIRES) mounted at Nasmyth A at the VLT (8.2 m UT1/Antu), Cerro Paranal, Chile. The observations were collected as part of the ESO large program 186.C-0289. The instrument setup consisted of a 0.2 arcsec slit centred on 3236nm (order 17), in combination with the Multi-Application Curvature Adaptive Optic system (MACAO). The CRIRES infrared detector is comprised of four Aladdin III InSb-arrays, each with 1024*512 pixels, and separated by a gap of 280 pixels. The resulting wavelength coverage of the observations was 3.1806R{approx}100000 per resolution element. We observed 51 Peg continuously while its hot Jupiter companion passed through orbital phases 0.55data are given in Table 1 and span observing dates from 1994 September 15 to 2014 July 9, resulting in 639 radial velocity measurements over 20 years. The table includes the discovery measurements from the ELODIE spectrograph at Observatoire Haute Provence and subsequent additional monitoring. We took these radial velocity measurements from the Naef et al. 2004 (Cat. J/A+A/414/351) compilation. We also included the legacy data set from Lick Observatory observed with the Hamilton spectrograph, taking measurements from the self-consistent reprocessing of all the Lick spectra presented by Fischer et al. 2014 (Cat. J/ApJS/210/5). Finally, we included more recent additional monitoring from the High Resolution Echelle Spectrometer (HIRES) at the Keck Observatory, and extracted RVs from observations with the High Accuracy Radial velocity Planet Searcher (HARPS) at the ESO-3.6m telescope in 2013 (ESO program ID 091.C-0271, PI: Santos). The reduced HARPS spectra were obtained from the ESO Science Archive (http://archive.eso.org/wdb/wdb/adp/phase3_spectral/query). (1 data file).

Variable Selection via Partial Correlation.

Science.gov (United States)

Li, Runze; Liu, Jingyuan; Lou, Lejia

2017-07-01

Partial correlation based variable selection method was proposed for normal linear regression models by Bühlmann, Kalisch and Maathuis (2010) as a comparable alternative method to regularization methods for variable selection. This paper addresses two important issues related to partial correlation based variable selection method: (a) whether this method is sensitive to normality assumption, and (b) whether this method is valid when the dimension of predictor increases in an exponential rate of the sample size. To address issue (a), we systematically study this method for elliptical linear regression models. Our finding indicates that the original proposal may lead to inferior performance when the marginal kurtosis of predictor is not close to that of normal distribution. Our simulation results further confirm this finding. To ensure the superior performance of partial correlation based variable selection procedure, we propose a thresholded partial correlation (TPC) approach to select significant variables in linear regression models. We establish the selection consistency of the TPC in the presence of ultrahigh dimensional predictors. Since the TPC procedure includes the original proposal as a special case, our theoretical results address the issue (b) directly. As a by-product, the sure screening property of the first step of TPC was obtained. The numerical examples also illustrate that the TPC is competitively comparable to the commonly-used regularization methods for variable selection.

An Optimised Aqueous Extract of Phenolic Compounds from Bitter Melon with High Antioxidant Capacity

Directory of Open Access Journals (Sweden)

Sing Pei Tan

2014-12-01

Full Text Available Bitter melon (Momordica charantia L. is a tropical fruit claimed to have medicinal properties associated with its content of phenolic compounds (TPC. The aim of the study was to compare water with several organic solvents (acetone, butanol, methanol and 80% ethanol for its efficiency at extracting the TPC from freeze-dried bitter melon powder. The TPC of the extracts was measured using the Folin-Ciocalteu reagent and their antioxidant capacity (AC was evaluated using three assays. Before optimisation, the TPC and AC of the aqueous extract were 63% and 20% lower, respectively, than for the best organic solvent, 80% ethanol. However, after optimising for temperature (80 °C, time (5 min, water-to-powder ratio (40:1 mL/g, particle size (1 mm and the number of extractions of the same sample (1×, the TPC and the AC of the aqueous extract were equal or higher than for 80% ethanol. Furthermore, less solvent (40 mL water/g and less time (5 min were needed than was used for the 80% ethanol extract (100 mL/g for 1 h. Therefore, this study provides evidence to recommend the use of water as the solvent of choice for the extraction of the phenolic compounds and their associated antioxidant activities from bitter melon.

Taipower's reload safety evaluation methodology for pressurized water reactors

International Nuclear Information System (INIS)

Huang, Ping-Hue; Yang, Y.S.

1996-01-01

For Westinghouse pressurized water reactors (PWRs) such as Taiwan Power Company's (TPC's) Maanshan Units 1 and 2, each of the safety analysis is performed with conservative reload related parameters such that reanalysis is not expected for all subsequent cycles. For each reload cycle design, it is required to perform a reload safety evaluation (RSE) to confirm the validity of the existing safety analysis for fuel cycle changes. The TPC's reload safety evaluation methodology for PWRs is based on 'Core Design and Safety Analysis Package' developed by the TPC and the Institute of Nuclear Energy Research (INER), and is an important portion of the 'Taipower's Reload Design and Transient Analysis Methodologies for Light Water Reactors'. The Core Management System (CMS) developed by Studsvik of America, the one-dimensional code AXINER developed by TPC, National Tsinghua University and INER, and a modified version of the well-known subchannel core thermal-hydraulic code COBRAIIIC are the major computer codes utilized. Each of the computer models is extensively validated by comparing with measured data and/or vendor's calculational results. Moreover, parallel calculations have been performed for two Maanshan reload cycles to validate the RSE methods. The TPC's in-house RSE tools have been applied to resolve many important plant operational issues and plant improvements, as well as to verify the vendor's fuel and core design data. (author)

Study the feasibility of hydrogen assisted renewable power for off-grid communities

International Nuclear Information System (INIS)

Wu, S.H.; Fleetwood, M.; Roberston, R.; Nielsen, N.

2004-01-01

Most Renewable energy sources lack the controllability and availability of conventional fossil fuel-based energy sources and therefore cannot meet load requirements of a community without a backup or storage system. The advances of hydrogen technologies enable these renewable energy options to supply power to remote communities relying on independent sources of electrical and other energy. The hydrogen assisted renewable power (HARP) concept promises to make renewable energy more practical and mainstream through the use of hydrogen based electrical generation systems. The study herein is the first of a multiphase project to investigate the benefits of HARP as an environmentally friendly replacement for diesel in the supply of electricity to off-grid communities and analyse its feasibility and suitability as a back-up power supply. A small-scale pilot project was selected and this study assesses the major elements of a plant required to integrate electrical generation system, hydrogen storage and hydrogen generation into a renewable energy generation system. Based on the available renewable energy profiles, a simulation model was developed to assist in selecting, integrating, and evaluating various configurations and operational scenarios. This paper describes the components of the proposed HARP system as well as its cost, benefits and opportunities for other applications. (author)

The Technical Communicator as Advocate: Integrating a Social Justice Approach in Technical Communication

Science.gov (United States)

Jones, Natasha N.

2016-01-01

This article argues for the need for a social justice approach to technical communication research and pedagogy. Given previous calls by scholars in technical and professional communication (TPC) for an attention to diversity, inclusion, and equality, the author examines the place and purpose of social justice in TPC and provides useful approaches…

A comparison of basal and eye-flush tears for the analysis of cat tear proteins.

Science.gov (United States)

Petznick, Andrea; Evans, Margaret D M; Madigan, Michele C; Markoulli, Maria; Garrett, Qian; Sweeney, Deborah F

2011-02-01

To identify a rapid and effective tear collection method providing sufficient tear volume and total protein content (TPC) for analysis of individual proteins in cats. Domestic adult short-haired cats (12-37 months; 2.7-6.6 kg) were used in the study. Basal tears without stimulation and eye-flush tears after instillation of saline (10 μl) were collected using microcapillary tubes from animal eyes either unwounded control or wounded with 9-mm central epithelial debridement giving four groups with n = 3. Tear comparisons were based on total time and rate for tear collection, TPC using micro bicinchoninic acid (BCA), tear immunoglobulin A (IgA), total matrix-metalloproteinase (MMP)-9 concentration using sandwich enzyme-linked immunosorbent assay (ELISA) and MMP-9 activity. Eye-flush tears were collected significantly faster than basal tears in wounded eyes with higher rates for tear collection in unwounded control and wounded eyes. TPC was significantly lower in eye-flush tears compared to basal tears. The relative proportion of tear IgA normalized to TPC (% IgA of TPC) was not significantly different between basal and eye-flush tears. In unwounded control eyes, MMP-9 was slightly higher in eye-flush than in basal tears; activity of MMP-9 in both tear types was similar. In wounded eyes, eye-flush tears showed highest MMP-9 levels and activity on Day 1, which subsequently decreased to Day 7. MMP-9 activity in basal tears from wounded eyes did not display changes in expression. Eye-flush tears can be collected rapidly providing sufficient tear volume and TPC. This study also indicates that eye-flush tears may be more suitable than basal tears for the analysis of MMPs following corneal wounding. © 2011 The Authors. Acta Ophthalmologica © 2011 Acta Ophthalmologica Scandinavica Foundation.

Influence of different extraction conditions on antioxidant properties of soursop peel.

Science.gov (United States)

Lee, Wei Zin; Chang, Sui Kiat; Khoo, Hock Eng; Sia, Chiaw Mei; Yim, Hip Seng

2016-01-01

Soursop is a healthy fruit. Peels form about 20% of the soursop fruit and are usually discarded as waste product. With a view to utilizing soursop peel as a source of valuable compounds, this study aimed to investigate the influence of different extraction conditions on total phenolic content (TPC) and antioxidant capacity (AC) of soursop (Annona muricata L.) peel. Different ethanol concentrations (20-100%, v/v), extraction temperatures (25- 60°C), and extraction time (1-5 h) were tested. Extracts were prepared on the basis of the best optimal extraction conditions (20% ethanol, 40°C the extraction temperature, and 4 h of extraction time), an optimal TPC and AC was determined for the soursop peel using DPPH, ABTS, FRAP and β-carotene bleaching (BCB) assays. The different extraction conditions tested at best optimum conditions have significantly affected the TPC and AC of the soursop peel. Soursop peel extract extracted in the best optimal extraction conditions had moderate levels of TPC (52.2 μg GAE/ml), and FRAP value (58.9 μg TE/ml extract). The extract demonstrated high BCB inhibitory activity (80.08%). The EC50 values of the extract were high, 1179.96 and 145.12 μg/ml, as assessed using DPPH and ABTS assays, respectively. The TPC was positively and highly correlated with the AC of soursop peel assessed by ABTS, FRAP, and BCB assay, but it was moderately correlated with DPPH radical scavenging activity. A moderate correlation of TPC with DPPH suggested that polyphenols in the extracts were partially responsible for the AC. By-products of soursop such as its peel could be an inexpensive source of good natural antioxidants with nutraceutical potential in the functional food industry.

Value and limitation of digital subtraction angiography for assessment of myocardial perfusion with varying coronary stenosis

International Nuclear Information System (INIS)

Ohtani, Nozomu

1988-01-01

We examined the value of digital subtraction angiography (DSA) for the assessment of regional myocardial perfusion by comparing with regional myocardial function in 10 anesthetized dogs. With varying degrees of reduction in left circumflex coronary artery (LCX) blood flow (CBF:categories of stenosis (S1-S5)), myocardial perfusion was assessed by injecting the contrast medium(1ml by power injector) selectively into LCX, and the regional myocardium with contrast was imaged with DSA. We recorded aortic pressure (AOP) and systolic wall thickening (%WTh: sonomicrometry) in the left ventricular posterior wall simultaneously with cine pulse. On the time-density curve obtained from the myocardial regin of interest, we calculated a time interval from the contrast injection to peak concentration (TPC) and exponential washout rate (T). Under varying LCX stenosis, there were no significant change of heart rate and mean AOP and a significant linear correlations were found between %WTh and both 1/TPC(r=0.51)and 1/T(r=0.55). At S1(CBF:100-90% of control), neither %WTh nor 1/TPC differed from control, but 1/T was significantly decreased (80% of contral p<0.01). At S3(CRF:79-60%) to S5(CBF:39-0%), all%WTh, 1/TPC and 1/T were significantly decreased from control (all p<0.01), however, at S5(CBF:39-0%) the value of 1/TPC(71% of control) and 1/T(33%) were not different from that at S4, whereas %WTh was markedly reduced and took place to systolic thinning.. Therefore, in critical coronary stenosis, 1/T was more sensitive than 1/TPC or wall dynamics for assessing myocardial perfusion, however, these indices from DSA had a considerable limitation for evaluating the severity of myocardial ischemia when CBF was markedly reduced. (author)

ARIADNE: Beam Time and Resources Request

CERN Document Server

Majumdar, K; McCormick, K J; Philippou, B; Roberts, A; Stavrakis, G; Touramanis, C; Vann, J

2017-01-01

The ARIADNE research programme is based around developing an optical readout system for use in LAr TPC detectors, which could potentially have a number of bene ts over the currently used segmented anode planes - particularly in matters of scalability for future kilo-tonne scale detectors, ease of installation, use and maintenance, and reconstruction resolution. As detailed in our previously submitted Letter of Intent (CERN-SPSC-2016-008 [SPSC-I-244]), ARIADNE itself is a 1-tonne, two-phase LAr TPC detector, designed and built at the University of Liverpool, which uses an array of EMCCD cameras as its optical readout system, alongside PMTs for scintillation light observation and a THGEM for charge readout. Once construction and initial calibration is completed at Liverpool, the detector's capabilities should be fully studied and characterised, and we would like to request 2 weeks of on-beam time at the CERN T9 beam line in the Spring of 2018 for this purpose. Due to the purity requirements and cryogenic nature...

Antioxidative activities and phenolic compounds of pumpkin (Cucurbita pepo) seeds and amaranth (Amaranthus caudatus) grain extracts.

Science.gov (United States)

Peiretti, Pier Giorgio; Meineri, Giorgia; Gai, Francesco; Longato, Erica; Amarowicz, Ryszard

2017-09-01

Phenolic compounds were extracted from pumpkin (Cucurbita pepo) seed and amaranth (Amaranthus caudatus) grain into 80% (v/v) methanol. The extracts obtained were characterised by the contents of total phenolic compounds (TPC), trolox equivalent antioxidant capacity (TEAC), ferric-reducing antioxidant power (FRAP) and antiradical activity against 2,2-diphenyl-1-picrylhydrazyl (DPPH · ) radical. The content of individual phenolic compounds was determined by HPLC-DAD method. Pumpkin seeds showed the higher content of TPC than that from amaranth. The TEAC values of both extracts were similar each other. The lower value of FRAP was observed for pumpkin seed. Phenolic compound present in amaranth grain exhibited strongest antiradical properties against DPPH radical. Several peaks were present on the HPLC chromatograms of two extracts. The UV-DAD spectra confirmed the presence of vanillic acid derivatives in the amaranth grain. The three main phenolic compound present in pumpkin seed were characterised by UV-DAD spectra with maximum at 258, 266 and 278 nm.

Application and performance of an ML-EM algorithm in NEXT

Science.gov (United States)

Simón, A.; Lerche, C.; Monrabal, F.; Gómez-Cadenas, J. J.; Álvarez, V.; Azevedo, C. D. R.; Benlloch-Rodríguez, J. M.; Borges, F. I. G. M.; Botas, A.; Cárcel, S.; Carrión, J. V.; Cebrián, S.; Conde, C. A. N.; Díaz, J.; Diesburg, M.; Escada, J.; Esteve, R.; Felkai, R.; Fernandes, L. M. P.; Ferrario, P.; Ferreira, A. L.; Freitas, E. D. C.; Goldschmidt, A.; González-Díaz, D.; Gutiérrez, R. M.; Hauptman, J.; Henriques, C. A. O.; Hernandez, A. I.; Hernando Morata, J. A.; Herrero, V.; Jones, B. J. P.; Labarga, L.; Laing, A.; Lebrun, P.; Liubarsky, I.; López-March, N.; Losada, M.; Martín-Albo, J.; Martínez-Lema, G.; Martínez, A.; McDonald, A. D.; Monteiro, C. M. B.; Mora, F. J.; Moutinho, L. M.; Muñoz Vidal, J.; Musti, M.; Nebot-Guinot, M.; Novella, P.; Nygren, D. R.; Palmeiro, B.; Para, A.; Pérez, J.; Querol, M.; Renner, J.; Ripoll, L.; Rodríguez, J.; Rogers, L.; Santos, F. P.; dos Santos, J. M. F.; Sofka, C.; Sorel, M.; Stiegler, T.; Toledo, J. F.; Torrent, J.; Tsamalaidze, Z.; Veloso, J. F. C. A.; Webb, R.; White, J. T.; Yahlali, N.

2017-08-01

The goal of the NEXT experiment is the observation of neutrinoless double beta decay in 136Xe using a gaseous xenon TPC with electroluminescent amplification and specialized photodetector arrays for calorimetry and tracking. The NEXT Collaboration is exploring a number of reconstruction algorithms to exploit the full potential of the detector. This paper describes one of them: the Maximum Likelihood Expectation Maximization (ML-EM) method, a generic iterative algorithm to find maximum-likelihood estimates of parameters that has been applied to solve many different types of complex inverse problems. In particular, we discuss a bi-dimensional version of the method in which the photosensor signals integrated over time are used to reconstruct a transverse projection of the event. First results show that, when applied to detector simulation data, the algorithm achieves nearly optimal energy resolution (better than 0.5% FWHM at the Q value of 136Xe) for events distributed over the full active volume of the TPC.

Preliminary results from the 2000 run of CERES on low-mass $e^{+}e^{-}$ pair production in Pb - Au collisions at 158 A GeV

CERN Document Server

Cherlin, A

2004-01-01

CERES has measured low-mass $e^{+}e^{-}$ pairs in Pb- Au collisions at 158 A GeV in the year 2000 Pb run at the SPS with the goal of shedding more light on the origin of the previously observed low-mass pair enhancement. The spectrometer was upgraded with a radial TPC to improve the mass resolution. A very effective rejection of the combinatorial background is achieved using the combined information of the two RICH detectors, the d$E$/dx signal of the doublet of silicon drift chambers, and the TPC track d$E$/dx information. Various steps and the current status of the data analysis are presented. Corrigendum. Table 1 and figures 3 and 4, as originally published, represent an earlier version of the data analysis. The corrected table and figures have been published as a Corrigendum (see below). The Corrigendum has also been appended at the end of the PDF file linked to this page.

Numerical Investigation on Electron and Ion Transmission of GEM-based Detectors

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Bhattacharya Purba

2018-01-01

Full Text Available ALICE at the LHC is planning a major upgrade of its detector systems, including the TPC, to cope with an increase of the LHC luminosity after 2018. Different R&D activities are currently concentrated on the adoption of the Gas Electron Multiplier (GEM as the gas amplification stage of the ALICE-TPC upgrade version. The major challenge is to have low ion feedback in the drift volume as well as to ensure a collection of good percentage of primary electrons in the signal generation process. In the present work, Garfield simulation framework has been adopted to numerically estimate the electron transparency and ion backflow fraction of GEM-based detectors. In this process, extensive simulations have been carried out to enrich our understanding of the complex physical processes occurring within single, triple and quadruple GEM detectors. A detailed study has been performed to observe the effect of detector geometry, field configuration and magnetic field on the above mentioned characteristics.

The effect of nisin from Lactococcus lactis subsp. lactis on refrigerated patin fillet quality

Science.gov (United States)

Adilla, S. N.; Utami, R.; Nursiwi, A.; Nurhartadi, E.

2017-04-01

The effect of nisin from Lactococcus lactis subsp. lactis with spraying method application on quality of patin fillet during refrigerated storage (4±1°C) was investigated. The quality of patin fillet based on total plate count (TPC), pH, TVB-N, and TBA values during 16 days at 4±1°C. Completely Randomized Design (CDR) was used in one factor (nisin activity) at 0 IU/ml, 500 IU/ml, 1000 IU/ml, and 2000 IU/ml. The observation was done at 0, 4th, 8th, 12th, and 16th days of storage. The result showed that variation of nisin activity significantly affected the quality of fillet according to TPC, pH, and TVB-N values, however no significant difference on the obtained of TBA value. Nisin in 500 IU/ml, 1000 IU/ml, and 2000 IU/ml could extend the shelf-life of fillet until 4th, 8th, and 12th days respectively based on standard in all parameters.

Numerical Investigation on Electron and Ion Transmission of GEM-based Detectors

Science.gov (United States)

Bhattacharya, Purba; Sahoo, Sumanya Sekhar; Biswas, Saikat; Mohanty, Bedangadas; Majumdar, Nayana; Mukhopadhyay, Supratik

2018-02-01

ALICE at the LHC is planning a major upgrade of its detector systems, including the TPC, to cope with an increase of the LHC luminosity after 2018. Different R&D activities are currently concentrated on the adoption of the Gas Electron Multiplier (GEM) as the gas amplification stage of the ALICE-TPC upgrade version. The major challenge is to have low ion feedback in the drift volume as well as to ensure a collection of good percentage of primary electrons in the signal generation process. In the present work, Garfield simulation framework has been adopted to numerically estimate the electron transparency and ion backflow fraction of GEM-based detectors. In this process, extensive simulations have been carried out to enrich our understanding of the complex physical processes occurring within single, triple and quadruple GEM detectors. A detailed study has been performed to observe the effect of detector geometry, field configuration and magnetic field on the above mentioned characteristics.

Microencapsulation of Thai rice grass (O. Sativa cv. Khao Dawk Mali 105) extract incorporated to form bioactive carboxymethyl cellulose edible film.

Science.gov (United States)

Rodsamran, Pattrathip; Sothornvit, Rungsinee

2018-03-01

Microencapsulation was investigated to enhance the stability of Thai rice grass extract. Microencapsulated powder (MP) was formed using total solid of extract solution and maltodextrin ratios of 1:4 (MP 1:4) and 1:9 (MP 1:9). The absence of an endothermic peak for both MPs confirmed all extract solutions were coated with maltodextrin. MP 1:9 had a lower total phenolic content (TPC) but was higher in antioxidant capacity than MP 1:4. Moreover, the TPC of the MPs slightly decreased (70.02-93.04%) during storage at 10, 30 and 70°C for 30d. Comparatively, the TPC of the extract solution significantly decreased from 100% down to 20.8%, 11.2% and 8.6% at 10, 30 and 70°C, respectively. Therefore, MP 1:9 incorporated with blended carboxymethyl cellulose film increased the water barrier and the TPC. This film can serve as a bioactive biodegradable packaging material to reduce plastic packaging in the food industry. Copyright © 2017 Elsevier Ltd. All rights reserved.

Measurements of ion mobility and GEM discharge studies for the upgrade of the ALICE time projection chamber

CERN Document Server

AUTHOR|(INSPIRE)INSPIRE-00507268

2018-02-20

ALICE is one of the four experiments at the Large Hadron Collider (LHC). The quark-gluon plasma, which is predominantly produced in lead-lead collisions at LHC, is of particular interest for ALICE. After the long shut-down 2 (2019-2021) the LHC will provide lead-lead collisions at an increased interaction rate of 50 kHz. In order to examine every event at this interaction rate the ALICE Time Projection Chamber (TPC) needs to be upgraded. The TPC’s ReadOut Chambers (ROCs) are currently multi-wire proportional chambers. To prevent space charge build-up of slow ions, drifting from the ROCs into the TPC, a gating grid is used. The corresponding closure time imposes a dead time on the TPC read out, which prohibits data taking at a readout rate higher than 3 kHz. New ROCs have therefore been designed, relying on stacks of Gas Electron Multiplier (GEM) foils for the gas amplification, allowing for continuous readout. With the new ROCs, a certain fraction of ions will be drifting at all time into the TPC. Knowing t...

Multi-elemental composition and antioxidant properties of strawberry tree (Arbutus unedo L.) honey from the coastal region of Croatia: Risk-benefit analysis.

Science.gov (United States)

Tariba Lovaković, Blanka; Lazarus, Maja; Brčić Karačonji, Irena; Jurica, Karlo; Živković Semren, Tanja; Lušić, Dražen; Brajenović, Nataša; Pelaić, Zdenka; Pizent, Alica

2018-01-01

The concentration of 23 major and trace elements, total phenolic content (TPC) and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity were determined in nine samples of strawberry tree honey and compared to other types of unifloral honeys. The most abundant elements in strawberry tree honey were potassium, calcium, magnesium and sodium, ranging between 1276 and 2367, 95.2-154, 14.4-74.4 and 13.4-64.3mg/kg, respectively. Strawberry tree honey had generally higher TPC (range: 0.314-0.522g GA/kg) and DPPH (1.94-4.45mM TE/kg) compared to other analysed unifloral honeys. A strong positive relationship was found between TPC and DPPH, TPC and concentration of homogentisic acid (HGA), chemical marker of strawberry tree honey, and between DPPH and HGA. Regarding daily intake of essential elements, strawberry tree honey can be considered nutritionally richer than the majority of unifloral honeys available in Croatia, while contribution to tolerable intake set for potentially toxic elements was very low, corresponding to pristine areas. Copyright © 2017 Elsevier GmbH. All rights reserved.

Antioxidant properties of selected fruit cultivars grown in Sri Lanka.

Science.gov (United States)

Silva, K D R R; Sirasa, M S F

2018-01-01

Extracts of twenty locally available Sri Lankan fruits were analysed for 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging activity, ferrous reducing antioxidant power (FRAP), total phenolic content (TPC), total flavonoid content (TFC) and vitamin C content. The results showed that gooseberry (Phyllanthus emblica 'local') exhibited the highest DPPH scavenging activity (111.25mg ascorbic acid equivalent antioxidant capacity (AEAC)/g), FRAP (1022.05μmol FeSO 4 /g), TPC (915.7mg gallic acid equivalents (GAE)/100g), TFC (873.2mg catechin equivalents (CE)/100g) and vitamin C (136.8mg ascorbic acid equivalents (AAE)/100g), respectively. Sugar apple (Annona squamosa 'local') and star fruit (Averrhoa carambola 'Honey Sweet') obtained the second and third highest antioxidant activities in terms of rankings of FRAP, DPPH activities, TPC, TFC and vitamin C content. Strong correlation between vitamin C, TPC and TFC with FRAP and DPPH showed their contribution to antioxidant capacity. Among the selected fruits, underutilized fruit cultivar gooseberry showed the highest overall antioxidant potential. Copyright © 2016 Elsevier Ltd. All rights reserved.

Optimization of an organic yogurt based on sensorial, nutritional, and functional perspectives.

Science.gov (United States)

Karnopp, Ariadne Roberto; Oliveira, Katherine Guimarães; de Andrade, Eriel Forville; Postingher, Bruna Mara; Granato, Daniel

2017-10-15

The effects of purple grape juice (PGJ), grape skin flour (GSF), and oligofructose (OLI) on proximate composition, total phenolic content (TPC), antioxidant activity (AA), sensory, physicochemical, and textural properties of yogurts were analyzed using response surface methodology. Multiple regression models were proposed and results showed that PGJ increased the viscosity, AA, and TPC, while GSF increased the ash and total fiber contents of yogurts. GSF and OLI increased the hardness and consistency. A simultaneous optimization was performed to maximize TPC, ash and fibers contents, and sensory acceptance: a yogurt containing 1.7% GSF and 8.0% PGJ had a high fiber (5.60±0.13%) and ash (0.76±0.02%) contents, TPC (28.32±2.10mg GAE/100g), AA toward DPPH (57.85±1.36mg AAE/100g), and total reducing capacity (28.86±5.19mg QE/100g). The optimized yogurt had 79% acceptability index, indicating the use of PGJ and GSF is a feasible alternative to increase the functional properties of yogurts. Copyright © 2017 Elsevier Ltd. All rights reserved.

Advancement in reactor coolant chemistry management programs and related technology development in Taiwan

International Nuclear Information System (INIS)

Huang, C.S.; Lin, Chien C.

2000-01-01

Taiwan Power Company (TPC) has three nuclear power plants in operation with a total capacity of 51 GWe, contributing about 30% of electricity generation in Taiwan. The first two plants, Chinshan (CSNPP) and Kuosheng (KSNPP), are boiling water reactor plants, and the third one, Maanshan (MASNPP), is a pressurized water reactor plant. Each plant has two identical reactors. As many nuclear power plant operators worldwide, TPC is committed to operate the plants efficiently, economically, and safely. TPC has developed and implemented several chemistry improvement programs in recent years to improve the coolant chemistry in order to ( l ) protect structure materials from corrosion, (2) reduce radiation exposures to workers and (3) reduce radwaste production and radiation release to the environment. This paper describes TPC's experience in some water chemistry management, radwaste reduction and radiation exposure control programs. Future programs under planning, including implementation of hydrogen water chemistry (HWC) in BWRs, installation of condensate pre-filters, and development of on-line water chemistry monitoring system, are also be briefly discussed. In addition, some material related research and development programs will also be presented. (author)

Mathematical Model of Piston Ring Sealing in Combustion Engine

Directory of Open Access Journals (Sweden)

Koszałka Grzegorz

2015-01-01

Full Text Available This paper presents a mathematical model of piston-rings-cylinder sealing (TPC of a combustion engine. The developed model is an itegrated model of gas flow through gaps in TPC unit, displacements and twisting motions of piston rings in ring grooves as well as generation of oil film between ring face surfaces and cylinder liner. Thermal deformations and wear of TPC unit elements as well as heat exchange between flowing gas and surrounding walls, were taken into account in the model. The paper contains descriptions of: assumptions used for developing the model, the model itself, its numerical solution as well as its computer application for carrying out simulation tests.

Analysis of data recorded by the LCTPC equipped with a two layer GEM-system

CERN Document Server

Ljunggren, M

2012-01-01

wire based readout. The prototype TPC is placed in a 1 Tesla magnet at DESY and tested using an electron beam. Analyses of data taken during two different measurement series, in 2009 and 2010, are presented here. The TPC was instrumented with a two layer GEM system and read out using modified electronics from the ALICE experiment, including the programmable charge sensitive preamp-shaper PCA16. The PCA16 chip has a number of programmable parameters which allows studies to determine the settings optimal to the final TPC. Here, the impact of the shaping time on the space resolution in the drift direction was studied. It was found that a shaping time of 60 ns is the b...

Strangeness production in p+Pb reactions at 200 GeV/c

International Nuclear Information System (INIS)

Greiner, D.E.; Andersen, E.; Blaes, R.; Cherney, M.; Cruz, B. de la; Fernandez, C.; Garabatos, C.; Garzon, J.A.; Geist, W.M.; Gruhn, C.R.; Hafidouni, M.; Hrubec, J.; Jones, P.G.; Judd, E.G.; Kuipers, J.P.M.; Ladrem, M.; Ladron de Guevara, P.; Loevhoeiden, G.; MacNaughton, J.; Mosquera, J.; Natkaniec, Z.; Nelson, J.M.; Neuhofer, G.; Perez de los Heros, C.; Plo, M.; Porth, P.; Powell, B.; Ramil, A.; Rohringer, H.; Sakrejda, I.; Thorsteinsen, T.F.; Traxler, J.; Voltolini, C.; Wozniak, K.; Yanez, A.; Zybert, R.

1994-01-01

The production of the strange particles Λ, anti Λ and K S 0 in p+Pb collisions at 200 GeV/c has been measured using the NA36 TPC. Rapidity distributions and multiplicity dependences are presented and compared to model calculations. Reinteractions in the target are important to describe the observed spectra. Inverse slopes T∼200 MeV are extracted from the transverse mass distributions. (orig.)

Separating true V0's from combinatoric background with a neural network

International Nuclear Information System (INIS)

Justice, M.

1997-01-01

A feedforward multilayered neural network has been trained to ''recognize'' true V0's in the presence of a large combinatoric background using simulated data for 2 GeV/nucleon Ni + Cu interactions. The resulting neural network filter has been applied to actual data from the EOS TPC experiment. An enhancement of signal to background over more traditional selection mechanisms has been observed. (orig.)

ICARUS+NESSiE: A proposal for short baseline neutrino anomalies with innovative LAr imaging detectors coupled with large muon spectrometers

Energy Technology Data Exchange (ETDEWEB)

Gibin, D., E-mail: daniele.gibin@pd.infn.it

2013-04-15

The proposal for an experimental search for sterile neutrinos beyond the Standard Model with a new CERN-SPS neutrino beam is presented. The experiment is based on two identical LAr-TPC's followed by magnetized spectrometers, observing the electron and muon neutrino events at 1600 and 300 m from the proton target. This project will exploit the ICARUS T600, moved from LNGS to the CERN “Far” position. An additional 1/4 of the T600 detector will be constructed and located in the “Near” position. Two spectrometers will be placed downstream of the two LAr-TPC detectors to greatly complement the physics capabilities. Comparing the two detectors, in absence of oscillations, all cross sections and experimental biases cancel out. Any difference of the event distributions at the locations of the two detectors might be attributed to the possible existence of ν-oscillations, presumably due to additional neutrinos with a mixing angle sin{sup 2}(2θ{sub new}) and a larger mass difference Δm{sub new}{sup 2}. The superior quality of the LAr imaging TPC, in particular its unique electron-π{sub 0} discrimination allows full rejection of backgrounds and offers a lossless ν{sub e} detection capability. The determination of the muon charge with the spectrometers allows the full separation of ν{sub μ} from anti-ν{sub μ} and therefore controlling systematics from muon mis-identification largely at high momenta.

Influence of extraction conditions on antioxidant properties of passion fruit (Passiflora edulis) peel.

Science.gov (United States)

Wong, Yuh Shan; Sia, Chiaw Mei; Khoo, Hock Eng; Ang, Yee Kwang; Chang, Sui Kiat; Chang, Sui Kiat; Yim, Hip Seng

2014-01-01

As a by-product of tropical fruit juice industry, passion fruit peel is a valuable functional food. It is rich in antioxidants. To determine its potential antioxidant properties of passion fruit peel, this study aimed to evaluate the effect of extraction conditions on total phenolic content and antioxidant activity. The extraction conditions were selected from different percentages of ethanol (0-100%, v/v), extraction times (60-300 min), and extraction temperatures (25-60°C) that based on the optimal percentage of DPPH radical scavenging activity. The selected extraction condition was applied for further determination of total phenolic content (TPC) of the passion fruit peel extract using Folin-Ciocalteu reagent assay, while the antioxidant activities were evaluated using DPPH and ABTS radicals scavenging assays, ferric reducing antioxidant power (FRAP), and β-carotene bleaching (BCB) assay. The best extraction conditions were 40% ethanol, 60 min extraction time, and extraction temperature of 30°C. The chosen extraction conditions have contributed to the high TPC and antioxidant activity of passion fruit peel. The levels of antioxidant activity obtained from the passion fruit peel were also lower compared to BHA and α-tocopherol. Positive correlations were observed between TPC and antioxidant activities as assessed by DPPH, ABTS, FRAP, and BCB assays. As a waste of passion fruit consumption or by-product of fruit juice industry, its peel could be considered as a potential source of natural antioxidant for possible functional food and industrial applications.

Hypoglycemic effect of basil (Ocimum basilicum) aqueous extract is mediated through inhibition of α-glucosidase and α-amylase activities: an in vitro study.

Science.gov (United States)

El-Beshbishy, Ha; Bahashwan, Sa

2012-02-01

The present study investigated the in vitro hypoglycemic activity of basil (Ocimum basilicum) aqueous extract. Preliminary phytochemical screening of the extract revealed the presence of reducing sugars, cardiac glycosides, tannins, saponins, glycosides, flavonoids and steroids. The total polyphenols content (TPC), flavonoids content (FC), percentage diphenylpicrylhydrazyl (DPPH( · )) radical inhibition and total antioxidant status (TAS) were estimated. The FC was 41 ± 2.2 rutin/g dry extract, the TPC was 146 ± 5.26 mg catechin/g dry extract and the TAS was 5.12 ± 0.7 mmol/L. The %DPPH( · ) free radical inhibition was 60%, 54%, 49% and 43%, respectively, for different extract concentrations; 20, 18.2, 16.3 and 14.5 mg/ml, respectively. The extract elicited significant dose-dependent pattern against rat intestinal sucrase (RIS; IC(50) = 36.72 mg/ml), rat intestinal maltase (RIM; IC(50) = 21.31 mg/ml) and porcine pancreatic α-amylase (PPA; IC(50) = 42.50 mg/ml) inhibitory activities. The inhibition was greater against maltase compared with sucrase. These effects may be attributed to the high TPC and FC levels. The linear regression analysis revealed strong significant positive correlations between %DPPH( · ) radical inhibition and each of %RIS, %RIM and %PPA inhibiting activity. Also, strong significant positive correlations between %RIS and either %RIM or %PPA inhibition activity were observed. We concluded therefore that basil aqueous extract via antioxidant and possibly α-glucosidase and α-amylase inhibiting activities, offered positive benefits to control diabetes.

Effect of five year storage on total phenolic content and antioxidant capacity of almond (Amygdalus communisL. hull and shell from different genotypes

Directory of Open Access Journals (Sweden)

Khadijeh Sadat Moosavi Dolatabadi

2014-12-01

Full Text Available Objectives: Almond (Prunus amygdalus hull and shell are agricultural by-products that are a source of phenolic compounds.The processing of almond produce shell and hull, accounts for more than 50% by dry weight of the almond fruits. Recently, more studies have focused on the influence of storage conditions and postharvest handling on the nutritional quality of fruits, especially the antioxidant phenolics. In this study, influence of long-term storage (five years on the total phenolic and antioxidant capacity of almond hull and shell from different genotypes was evaluated. Materials and Methods: The fruits of subjected genotypes were collected and their hull and shell were separated. They were dried and reduced to fine powder. This powder stored at room temperature for five years. The total phenolic content (TPC and bioactivities (antioxidant potential: DPPH and ABTS radical scavenging and reducing power of extracts were evaluated using spectrophotometric methods. Results: It was found that TPC content and bioactivity levels in the stored almond hull and shell were different, compared to the hulls and shells which were evaluated in 2007. S1-4 genotype had the highest TPC and reducing power in its hull and shell.Low correlation coefficient was observed between phenolic content and the DPPH radical scavenging percentage in hull and shell extract. Conclusions: For the first time, results of this investigation showed that storage can influence the antioxidant and antiradical potential of almond hull and shell.

Trabalho de casa, tarefas escolares, auto-regulação e envolvimento parental Homework, self-regulated learning and parent involvement

Directory of Open Access Journals (Sweden)

Pedro Rosário

2005-12-01

Full Text Available Urge entender o Trabalho de Casa (TPC como processo complexo para o qual conflui um vasto leque de factores impactantes. Neste relato analisam-se as relações entre os perfis de atitudes e comportamentos diante do TPC de Inglês e o nível instrutivo dos pais, a auto-eficácia percebida nessa disciplina bem como a correlação entre tais perfis de TPC e os perfis auto-regulatórios, em face do estudo. A amostra tomada é composta de 3929 alunos. O nível instrutivo dos pais associa-se positiva e significativamente aos perfis de atitudes e comportamentos de TPC. As atitudes e comportamentos de TPC correlacionam-se, positiva e significativamente, com os perfis auto-regulatórios, diante do estudo. Alunos que se percepcionam como mais auto-eficazes registam melhores perfis de atitudes e comportamentos de TPC. Os resultados sugerem a necessidade de os diferentes parceiros do sistema educativo analisarem e promoverem activamente os processos auto-regulatórios envolvidos no ensino-aprendizagem em geral e no TPC em particular.There is a need to view homework (HW as a process for which a vast number of obstructive factors converges. In this report the interrelations between students of English as a Foreign Language, homework attitudes and behaviors, and their parents' education and students' perceived self-efficacy in EFL are analyzed. The correlation between students' EFL homework attitudes and behaviors and students' self-regulated learning profiles are also discussed. The study involved 3929 students, from 5th to 9th grades compulsory education. The collected data evidenced the positive and significant associations between EFL students' attitudes and behaviors towards homework and the parents' education and students' perceived self-efficacy in EFL. The correlation between EFL students' attitudes and behaviors towards homework and students' self-regulated learning profiles proves to be positive and significant. Calling the attention of teachers and

Tree age, fruit size and storage conditions affect levels of ascorbic acid, total phenolic concentrations and total antioxidant activity of 'Kinnow' mandarin juice.

Science.gov (United States)

Khalid, Samina; Malik, Aman U; Khan, Ahmad S; Shahid, Muhammad; Shafique, Muhammad

2016-03-15

Bioactive compounds (ascorbic acid, total phenolics and total antioxidants) are important constituents of citrus fruit juice; however, information with regard to their concentrations and changes in relation to tree age and storage conditions is limited. 'Kinnow' (Citrus nobilis Lour × Citrus deliciosa Tenora) mandarin juice from fruit of three tree ages (6, 18 and 35 years old) and fruit sizes (large, medium and small) were examined for their bioactive compounds during 7 days under ambient storage conditions (20 ± 2 °C and 60-65% relative humidity (RH)) and during 60 days under cold storage (4 ± 1 °C and 75-80% RH) conditions. Under ambient conditions, a reduction in total phenolic concentrations (TPC) and in total antioxidant activity (TAA) was found for the juice from all tree ages and fruit sizes. Overall, fruit from 18-year-old trees had higher mean TPC (95.86 µg mL(-1) ) and TAA (93.68 mg L(-1) ), as compared to 6 and 35-year-old trees. Likewise, in cold storage, TAA decreased in all fruit size groups from 18 and 35-year-old trees. In all tree age and fruit size groups, TPC decreased initially during 15 days of cold storage and then increased gradually with increase in storage duration. Ascorbic acid concentrations showed an increasing trend in all fruit size groups from 35-year-old trees. Overall, during cold storage, fruit from 18-year-old trees maintained higher mean ascorbic acid (33.05 mg 100 mL(-1) ) concentrations, whereas fruit from 6-year-old trees had higher TAA (153.1 mg L(-1) ) and TPC (115.1 µg mL(-1) ). Large-sized fruit had higher ascorbic acid (32.08 mg 100 mL(-1) ) concentrations and TAA (157.5 mg L(-1) ). Fruit from 18-year-old trees maintained higher TPC and TAA under ambient storage conditions, whereas fruit from 6-year-old trees maintained higher TPC and TAA during cold storage. Small-sized fruit had higher TPC after ambient temperature storage, whereas large fruit size showed higher ascorbic acid concentrations and TAA after cold

Radial velocity follow-up of CoRoT transiting exoplanets

Directory of Open Access Journals (Sweden)

Deleuil M.

2011-02-01

Full Text Available We report on the results from the radial-velocity follow-up program performed to establish the planetary nature and to characterize the transiting candidates discovered by the space mission CoRoT. We use the SOPHIE at OHP, HARPS at ESO and the HIRES at Keck spectrographs to collect spectra and high-precision radial velocity (RV measurements for several dozens different candidates from CoRoT. We have measured the Rossiter-McLaughlin effect of several confirmed planets, especially CoRoT-1b which revealed that it is another highly inclined system. Such high-precision RV data are necessary for the discovery of new transiting planets. Furthermore, several low mass planet candidates have emerged from our Keck and HARPS data.

Childhood traumatization by primary caretaker and affect dysregulation in patients with borderline personality disorder and somatoform disorder

Directory of Open Access Journals (Sweden)

Annemiek van Dijke

2011-03-01

Full Text Available Affect regulation is often compromised as a result of early life interpersonal traumatization and disruption in caregiving relationships like in situations where the caretaker is emotionally, sexually or physically abusing the child. Prior studies suggest a clear relationship between early childhood attachment-related psychological trauma and affect dysregulation. We evaluated the relationship of retrospectively recalled childhood traumatization by primary caretaker(s (TPC and affect dysregulation in 472 adult psychiatric patients diagnosed with borderline personality disorder (BPD, somatoform disorder (SoD, both BPD and SoD, or disorders other than BPD or SoD, using the Bermond-Vorst Alexithymia Questionnaire, the self-report version of the Structured Interview for Disorders of Extreme Stress, the Self-rating Inventory for Posttraumatic Stress Disorder (SRIP and the Traumatic Experiences Checklist. Almost two-thirds of participants reported having experienced childhood TPC, ranging from approximately 50% of patients with SoD or other psychiatric disorders to more than 75% of patients with comorbid BPD + SoD. Underregulation of affect was associated with emotional TPC and TPC occurring in developmental epoch 0–6 years. Over-regulation of affect was associated with physical TPC. Childhood trauma by a primary caretaker is prevalent among psychiatric patients, particularly those with BPD, and differentially associated with underand over-regulation of affect depending on the type of traumatic exposure.For the abstract or full text in other languages, please see Supplementary files under Reading Tools online

Antioxidant Capacity and Total Phenolic Compounds of Twelve Selected Potato Landrace Clones Grown in Southern Chile Capacidad Antioxidante y Compuestos Fenólicos totales de una Selección de Doce Variedades Tradicionales de Papa Cultivadas en la Región Sur de Chile

Directory of Open Access Journals (Sweden)

Kong Ah-Hen

2012-03-01

Full Text Available Colored potatoes (Solanum tuberosum L. provide a natural source of phytochemicals that help reduce the risk of diseases. However, there is a lack of information on the degree of variation of the antioxidant activity and polyphenolic contents of these native potatoes. Thus, the antioxidant activity (AA and total phenolic content (TPC of native Chilean potatoes were determined. Twelve potato landrace clones collected from established cultivations on Chiloe Island and Valdivia were selected. Total phenolic content and AA were compared with two commercial varieties, Shepody and Desirée. Total phenolic content was determined by the Folin-Ciocalteu method, and β-carotene bleaching was used to compare AA. The TPC varied in the peeled potato samples from 191 to 1864 mg 100 g-1 DM meanwhile these parameters varied from 345 to 2852 mg 100 g-1 DM in unpeeled samples. Antioxidant activity was higher in unpeeled potatoes, and was the highest in the unpeeled NG-6 or 'Bruja' native potato. The commercial var. Shepody showed pro-oxidant activity and had a relatively lower TPC. Results also indicated a higher concentration of total phenolics in the periderm of the colored native Chilean potatoes.Las papas (Solanum tuberosum L. coloreadas son una fuent natural de fitoquímicos que ayudan a reducir el riesgo de enfermedades. Sin embargo, existe una falta de información sobre el grado de variación de la actividad antioxidante y el contenido de polifenoles en estas papas nativas. Es así como la actividad antioxidante (AA y contenido de fenoles totales (TPC se determinaron en papas nativas chilenas. Doce genotipos de papa recogidos de cultivos establecidos en la Isla de Chiloé y en Valdivia fueron seleccionados, y se compararon TPC y AA con dos variedades comerciales, Shepody y Desirée. El TPC se determinó por el método de Folin-Ciocalteu, y el blanqueamiento de p-caroteno se utilizó para comparar la AA. El TPC varió en las muestras de papas sin piel desde

Correlation of pasting behaviors with total phenolic compounds and starch digestibility of indigenous pigmented rice grown in upper Northern Thailand

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Jirapa Ponjanta

2016-03-01

Full Text Available Background: Thailand has one of the most important rice genetic resources with white, light brown, brown, red, and purple rice bran colors. The latter believed to have potential for health benefits due to their phenolic content. Recently researchers have indicated that starch digestive enzymes, including salivary and pancreatic α-amylases and α-glucosidases, can be inhibited by phenolic compounds. Although pasting properties of rice flour are key determinants of quality significantly impacting the final product texture, there is no in-depth study on their correlation with phenolic compound and starch digestibility. Methods: Rice flour from twelve varieties, three from each of five bran colors (white, brown, red, and purple, were evaluated for pasting properties (RVA-3D, total phenolic compounds, amylose content, resistant starch and estimated glycemic index. Simple correlation coefficients were calculated for the relationships between pasting properties (final viscosity, breakdown, setback and pasting temperature and total phenolic compounds, resistant starch and estimated glycemic index. Results: Within each rice variety, red and purple pigmented flours had higher total phenolic compounds (TPC and more resistant starch than that of white flours. The TPC and resistant starch content of the flours ranged between 7.83- 47.3 mg/L and 2.44–10.50% respectively, and producing 60-80 of estimated glycemic index. Viscosity behavior showed that pigmented with low amylose rice had lower viscosity temperature than that of pigmented with high amylose rice flour, but higher in peak viscosity. Correlation coefficients of pasting temperature, final viscosity, break down and setback with TCP was observed to be inversely related to glycemic index. However, it was positively correlated to the resistant starch and amylose content. Conclusions: Pigmented rice flour is a better source of TPC and resistant starch which in turn provides low glycemic index. This

Report on Fission Time Projection Chamber M3FT-12IN0210052

Energy Technology Data Exchange (ETDEWEB)

James K. Jewell

2012-08-01

The Time Projection Chamber is a collaborative effort to implement an innovative approach and deliver unprecedented fission measurements to DOE programs. This 4?-detector system will provide unrivaled 3-D data about the fission process. Shown here is a half populated TPC (2?) at the LLNL TPC laboratory as it undergoes testing before being shipped to LANSCE for beam experiments.

Tracking Performance in High Multiplicity Environment for the CLIC ILD Detector

CERN Document Server

Killenberg, M

2012-01-01

We report on the tracking efficiency and the fraction of badly reconstructed tracks in the CLIC ILD detector for high multiplicity events (tt ̄@3 TeV) with and without the presence of γγ →hadrons background. They have been studied for the silicon tracking, the TPC tracking and the so called FullLDC tacking, which combines silicon and TPC measurements.

ALICE chip processor

CERN Multimedia

Maximilien Brice

2003-01-01

This tiny chip provides data processing for the time projection chamber on ALICE. Known as the ALICE TPC Read Out (ALTRO), this device was designed to minimize the size and power consumption of the TPC front end electronics. This single chip contains 16 low-power analogue-to-digital converters with six million transistors of digital processing and 8 kbits of data storage.

The Development of a Benchmark Tool for NoSQL Databases

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Ion LUNGU

2013-07-01

Full Text Available The aim of this article is to describe a proposed benchmark methodology and software application targeted at measuring the performance of both SQL and NoSQL databases. These represent the results obtained during PhD research (being actually a part of a larger application intended for NoSQL database management. A reason for aiming at this particular subject is the complete lack of benchmarking tools for NoSQL databases, except for YCBS [1] and a benchmark tool made specifically to compare Redis to RavenDB. While there are several well-known benchmarking systems for classical relational databases (starting with the canon TPC-C, TPC-E and TPC-H, on the other side of databases world such tools are mostly missing and seriously needed.

Development and characterization of micro-pattern gas detectors for intense beams of hadrons

Energy Technology Data Exchange (ETDEWEB)

Vandenbroucke, Maxence

2012-07-02

This thesis work is dedicated to the design, development and characterization of Micro-Pattern Gas Detectors. The performances of a Time Projection Chamber (TPC) equipped with a triple Gas Electron Multiplier (GEM) amplification structure are reported. The intrinsic ion backflow suppression of GEM foils drastically reduces the space charge produced by wire readout in traditional TPC. The GEM solution allows the operation of a TPC at much higher event rate. The second part of this thesis describes the development of a 40 x 40 cm{sup 2} Micromegas detector with a highly segmented central area. A reduction of discharges compared to conventional Micromegas detectors is needed for stable operation in intense beams of hadrons. Spark reduction technologies have been successfully studied and results are presented.

Development and characterization of micro-pattern gas detectors for intense beams of hadrons

International Nuclear Information System (INIS)

Vandenbroucke, Maxence

2012-01-01

This thesis work is dedicated to the design, development and characterization of Micro-Pattern Gas Detectors. The performances of a Time Projection Chamber (TPC) equipped with a triple Gas Electron Multiplier (GEM) amplification structure are reported. The intrinsic ion backflow suppression of GEM foils drastically reduces the space charge produced by wire readout in traditional TPC. The GEM solution allows the operation of a TPC at much higher event rate. The second part of this thesis describes the development of a 40 x 40 cm 2 Micromegas detector with a highly segmented central area. A reduction of discharges compared to conventional Micromegas detectors is needed for stable operation in intense beams of hadrons. Spark reduction technologies have been successfully studied and results are presented.

The exoplanet-host star {mu} Arae: a new seismic analysis

Energy Technology Data Exchange (ETDEWEB)

Soriano, M; Vauclair, S [Laboratoire d' Astrophysique Toulouse-Tarbes - OMP, 14 avenue Edouard Belin, 31400 Toulouse (France)], E-mail: sylvie.vauclair@ast.obs-mip.fr

2008-10-15

We present here the detailled modelling of the exoplanet-host star {mu} Arae, which is known to harbour a four-planets system. This star presents a metallicity excess compared to stars without detected planets. Asteroseismology can help determining precisely its internal structure, {mu} Arae was observed with the HARPS spectrograph at La Silla Observatory in June 2004, and 43 p-modes were identified. Using the external parameters provided by spectroscopy and the seismic constraints, we computed new stellar models, in a wider range and more precisely than [1], with various assumptions (overmetallic or accretion scenario, overshooting or not, Y enriched with metals or Y fixed to its solar value). We tried to find which ones give the best fit to the observations.

Bats from Fazenda Intervales, Southeastern Brazil: species account and comparison between different sampling methods

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Christine V. Portfors

2000-06-01

Full Text Available Assessing the composition of an area's bat fauna is typically accomplished by using captures or by monitoring echolocation calls with bat detectors. The two methods may not provide the same data regarding species composition. Mist nets and harp traps may be biased towards sampling low flying species, and bat detectors biased towards detecting high intensity echolocators. A comparison of the bat fauna of Fazenda Intervales, southeastern Brazil, as revealed by mist nets and harp trap captures, checking roosts and by monitoring echolocation calls of flying bats illustrates this point. A total of 17 species of bats was sampled. Fourteen bat species were captured and the echolocation calls of 12 species were recorded, three of them not revealed by mist nets or harp traps. The different sampling methods provided different pictures of the bat fauna. Phyllostomid bats dominated the catches in mist nets, but in the field their echolocation calls were never detected. No single sampling approach provided a complete assessment of the bat fauna in the study area. In general, bats producing low intensity echolocation calls, such as phyllostomids, are more easily assessed by netting, and bats producing high intensity echolocation calls are better surveyed by bat detectors. The results demonstrate that a combined and varied approach to sampling is required for a complete assessment of the bat fauna of an area.

SPITZER OBSERVATIONS OF GJ 3470 b: A VERY LOW-DENSITY NEPTUNE-SIZE PLANET ORBITING A METAL-RICH M DWARF

International Nuclear Information System (INIS)

Demory, Brice-Olivier; Seager, Sara; Torres, Guillermo; Neves, Vasco; Santos, Nuno; Rogers, Leslie; Gillon, Michaël; Horch, Elliott; Sullivan, Peter; Bonfils, Xavier; Delfosse, Xavier; Forveille, Thierry; Lovis, Christophe; Mayor, Michel; Udry, Stephane; Smalley, Barry

2013-01-01

We present Spitzer/IRAC 4.5 μm transit photometry of GJ 3470 b, a Neptune-size planet orbiting an M1.5 dwarf star with a 3.3 day period recently discovered in the course of the HARPS M-dwarf survey. We refine the stellar parameters by employing purely empirical mass-luminosity and surface brightness relations constrained by our updated value for the mean stellar density, and additional information from new near-infrared spectroscopic observations. We derive a stellar mass of M * = 0.539 +0.047 -0.043 M sun and a radius of R * = 0.568 +0.037 -0.031 R sun . We determine the host star of GJ 3470 b to be metal-rich, with a metallicity of [Fe/H] = +0.20 ± 0.10 and an effective temperature of T eff = 3600 ± 100 K. The revised stellar parameters yield a planetary radius R p = 4.83 -0.21 +0.22 R ⊕ that is 13% larger than the value previously reported in the literature. We find a planetary mass M p = 13.9 +1.5 -1.4 M ⊕ that translates to a very low planetary density, ρ p = 0.72 +0.13 -0.12 g cm –3 , which is 33% smaller than the original value. With a mean density half of that of GJ 436 b, GJ 3470 b is an example of a very low-density low-mass planet, similar to Kepler-11 d, Kepler-11 e, and Kepler-18 c, but orbiting a much brighter nearby star that is more conducive to follow-up studies.

Temperature Stabilization of the NIFFTE Time Projection Chamber

Science.gov (United States)

Hicks, Caleb

2017-09-01

The Neutron Induced Fission Fragment Tracking Experiment (NIFFTE) is a collaboration measuring nuclear fission cross sections for use in advanced nuclear reactors. A neutron beam incident on targets of Uranium-235, Uranium-238, and Plutonium-239 is used to measure the neutron induced fission cross sections for these isotopes. A Time Projection Chamber (TPC) is used to record these reactions. Significant heat is generated by the readout cards mounted on the TPC, which are cooled by fans. One proposed measurement of the experiment is to compare the cross sections of the target to a proton target of gaseous hydrogen. A constant temperature inside the TPC's pressure vessel is desirable to maintain a constant number of hydrogen target atoms. In addition, a constant temperature minimizes the strain and wrinkles on an amplifying mesh inside the TPC. This poster describes the successful work to develop, build, and install a fan controller using a Raspberry Pi, an Arduino, and a custom circuit board to implement an algorithm called Proportional-Integral-Derivative control. This research was supported by US DOE MENP Grant DE-FG02-03ER41243.

Ionization Electron Signal Processing in Single Phase LArTPCs II. Data/Simulation Comparison and Performance in MicroBooNE

Energy Technology Data Exchange (ETDEWEB)

Adams, C.; et al.

2018-04-07

The single-phase liquid argon time projection chamber (LArTPC) provides a large amount of detailed information in the form of fine-grained drifted ionization charge from particle traces. To fully utilize this information, the deposited charge must be accurately extracted from the raw digitized waveforms via a robust signal processing chain. Enabled by the ultra-low noise levels associated with cryogenic electronics in the MicroBooNE detector, the precise extraction of ionization charge from the induction wire planes in a single-phase LArTPC is qualitatively demonstrated on MicroBooNE data with event display images, and quantitatively demonstrated via waveform-level and track-level metrics. Improved performance of induction plane calorimetry is demonstrated through the agreement of extracted ionization charge measurements across different wire planes for various event topologies. In addition to the comprehensive waveform-level comparison of data and simulation, a calibration of the cryogenic electronics response is presented and solutions to various MicroBooNE-specific TPC issues are discussed. This work presents an important improvement in LArTPC signal processing, the foundation of reconstruction and therefore physics analyses in MicroBooNE.

Investigation on interlaminar shear strength properties of disc laser machined consolidated CF-PPS laminates

Directory of Open Access Journals (Sweden)

2011-03-01

Full Text Available In consequence of an increased interest in using endless carbon fibre reinforced thermoplastic composites (TPC, automated and highly productive processing technologies for cutting and trimming steps of consolidated materials are sought. In this paper, the influence on the thermal effect caused by laser cutting with respect to static strength properties of TPC based on a polyphenylene sulfide (PPS matrix is studied. For the cutting experiments, consolidated TPC laminates at varying thicknesses up to s = 3.1 mm and a disc laser emitting at a wavelength of λ = 1030 nm at a maximum output power of PL = 2 kW are used. For the first time, the resulting magnitude of the heat affected zone (HAZ at the cutting edge of the composite material is correlated with interlaminar shear strength tests. The results are compared to specimens prepared by milling and abrasive water jet cutting. Depending on the laminate thickness, the laser treated TPC samples show comparable properties to those of conventionally processed specimens. A reduced load bearing area, as a consequence of damaged fibre-matrix-adhesion due to laser impact, is identified as main factor for the reduction of interlaminar shear strengths for higher laminate thicknesses.

High-performance size-exclusion chromatography studies on the formation and distribution of polar compounds in camellia seed oil during heating*

Science.gov (United States)

Feng, Hong-xia; Sam, Rokayya; Jiang, Lian-zhou; Li, Yang; Cao, Wen-ming

2016-01-01

Camellia seed oil (CSO) is rich in oleic acid and has a high number of active components, which give the oil high nutritional value and a variety of biological activity. The aim of the present study was to determine the changes in the content and distribution of total polar compounds (TPC) in CSO during heating. TPC were isolated by means of preparative flash chromatography and further analyzed by high-performance size-exclusion chromatography (HPSEC). The TPC content of CSO increased from 4.74% to 25.29%, showing a significantly lower formation rate as compared to that of extra virgin olive oil (EVOO) and soybean oil (SBO) during heating. Furthermore, heating also resulted in significant differences (P<0.05) in the distribution of TPC among these oils. Though the content of oxidized triacylglycerol dimers, oxidized triacylglycerol oligomers, and oxidized triacylglycerol monomers significantly increased in all these oils, their increased percentages were much less in CSO than those in EVOO, indicating that CSO has a greater ability to resist oxidation. This work may be useful for the food oil industry and consumers in helping to choose the correct oil and to decide on the useful lifetime of the oil. PMID:27819135

Studies for a silicon telescope to extend the magnet facility at the DESY test beam

Energy Technology Data Exchange (ETDEWEB)

Tsionou, Dimitra [Deutsches Elektronen-Synchrotron (DESY), Notkestrasse 85, 22607 Hamburg (Germany)

2016-07-01

The International Large Detector is a detector concept for the International Linear Collider (ILC) which uses a Time Projection Chamber (TPC) as its main tracking detector. Within the framework of the LCTPC collaboration, a large prototype (LP) TPC has been built as a demonstrator. The LP has been equipped with Micro-Pattern Gas Detector modules and studied with an electron beam (1-6 GeV) in a 1 Tesla magnetic field at DESY. To extend the capabilities of the test beam setup, an external silicon tracker to be installed inside the magnet will be discussed. The silicon detector will provide high precision space points in front and behind the TPC inside the magnet. It will provide reference tracks that will allow to determine the momentum of the tracks passing the TPC, and which will help in correcting for field distortion effects in the LPTPC volume. In order to meet these requirements, simulation studies have been performed to determine the layout of the system and have placed stringent requirements on the sensor spatial resolution of better than 10 μ m. These studies will be presented along with the hardware options under evaluation.

Antioxidant potential of brans of twenty-nine red and white rice (Oryza sativa L. varieties of Sri Lanka

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Walimuni Kanchana Subhashini Mendis Abeysekera

2017-11-01

Full Text Available Objective: To evaluate antioxidant properties of brans of twenty-nine red and white rice varieties of Sri Lanka. Methods: Brans of 21 new improved (NI, 2 old improved (OI and 6 traditional red and white rice varieties of Sri Lanka were studied for range of antioxidant properties. The studied antioxidant properties included total polyphenolic content (TPC, ferric reducing antioxidant power (FRAP, oxygen radical absorbance capacity (ORAC, 2,2’-azino-bis(3- ethylbenzothiazoline-6-sulfonic acid (ABTS radical scavenging activity and 1,1-diphenyl- 2-picrylhydrazine (DPPH radical scavenging activity in vitro. Bran of black rice variety from Korea was also studied for the same antioxidant properties for comparison. Results: Results exhibited significantly high ABTS and DPPH radical scavenging activities and 10, 7 and 2.5 fold greater TPC, FRAP and ORAC activities in brans of red rices (BRRs compared to brans of white rices irrespective of NI, OI and traditional rice types. Among BRRs traditional varieties had greater ABTS and DPPH radical scavenging activities and 1.7, 1.3 and 1.2 fold respectively greater TPC, FRAP and ORAC in contrast to NI red rices. Traditional red rice varieties, Kalu Heeneti (TPC and ORAC, Pachchaperumal (TPC and DPPH and Kurulu Thuda (DPPH and OI red rice variety H4 (FRAP exhibited the highest activities for the antioxidant properties studied. Further, these varieties had significantly high activities compared to black rice. Conclusions: In conclusion, BRRs especially traditional red rices had greater antioxidant properties and consumption may be useful in managing various chronic diseases.

Optimization of extraction parameters on the antioxidant properties of banana waste.

Science.gov (United States)

Toh, Pui Yee; Leong, Fei Shan; Chang, Sui Kiat; Khoo, Hock Eng; Yim, Hip Seng

2016-01-01

Banana is grown worldwide and consumed as ripe fruit or used for culinary purposes. Peels form about 18-33% of the whole fruit and are discarded as a waste product. With a view to exploiting banana peel as a source of valuable compounds, this study was undertaken to evaluate the effect of different extraction parameters on the antioxidant activities of the industrial by-product of banana waste (peel). Influence of different extraction parameters such as types of solvent, percentages of solvent, and extraction times on total phenolic content (TPC) and antioxidant activity of mature and green peels of Pisang Abu (PA), Pisang Berangan (PB), and Pisang Mas (PM) were investigated. The best extraction parameters were initially selected based on different percentages of ethanol (0-100% v/v), extraction time (1-5 hr), and extraction temperature (25-60°C) for extraction of antioxidants in the banana peels. Total phenolic content (TPC) was evaluated using Folin-Ciocalteu reagent assay while antioxidant activities (AA) of banana peel were accessed by DPPH, ABTS, and β-carotene bleaching (BCB) assays at optimum extraction conditions. Based on different extraction solvents and percentages of solvents used, 70% and 90% of acetone had yielded the highest TPC for the mature and green PA peels, respectively; 90% of ethanol and methanol has yielded the highest TPC for the mature and green PB peels, respectively; while 90% ethanol for the mature and green PM peels. Similar extraction conditions were found for the antioxidant activities for the banana peel assessed using DPPH assay except for green PB peel, which 70% methanol had contributed to the highest AA. Highest TPC and AA were obtained by applying 4, 1, and 2 hrs extraction for the peels of PA, PB and PM, respectively. The best extraction conditions were also used for determination of AAs using ABTS and β-carotene bleaching assays. Therefore, the best extraction conditions used have given the highest TPC and AAs. By

Toxicological assessment of crude palm oil (Elaeis guineensis Jacq. used in deep frying of akara (cowpea paste finger food

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Felzenszwalb, I.

2014-06-01

Full Text Available Akara is cowpea paste which is deep-fried in crude palm oil (CPO; Elaeis guineensis Jacq. and sold as a street finger food in Brazil and Africa. During the food frying oils can form toxic decomposition products as total polar compounds (TPC, which can determinate oil degradation. The aim of this study was to assess the toxicity of CPO used in akara frying for 25 hours. Changes in the oil were determined by TPC quantification and mutagenicity using a Salmonella/microssome assay with Salmonella Typhimurium strains TA97, TA98, TA100 and TA102 with and without exogenous metabolic activation. Assuming that 25% TPC is the maximum level permitted in frying oils and it ranged from 14.08 to 29.81%, frying palm oil exceeded the limit. Nonetheless, no cytotoxic, mutagenic or genotoxic activity were detected in CPO used in the traditional akara frying process.Akara es una tapa hecha de pasta de frijol frito en aceite de palma crudo (CPO; Elaeis guineensis, que se vende en las calles de Brasil y África. Durante la fritura de alimentos, los aceites pueden formar productos de descomposición tóxicos como los compuestos polares totales (TPC, que determinan la degradación del aceite. El objetivo de este estudio fue evaluar la toxicidad de CPO utilizado en 25 horas de frituras de akara. Los cambios en el aceite se determinaron mediante la cuantificación de TPC y ensayos de mutagenicidad en Salmonella microsomas usando cepas de Salmonella Typhimurium TA97, TA98, TA100 y TA102 con y sin activación metabólica exógena. Se asume que el 25% de TPC es el nivel máximo permitido, los aceites de fritura oscilaron desde 14,08 hasta 29,81%. Ningún CPO utilizado en el proceso de akara tradicional mostró ser citotóxico, ni tener actividad mutagénica o genotóxica.

In Vitro Antioxidant and Cytotoxic Activities of Arnebia benthamii (Wall ex. G. Don: A Critically Endangered Medicinal Plant of Kashmir Valley

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Showkat Ahmad Ganie

2014-01-01

Full Text Available Arnebia benthamii is a major ingredient of the commercial drug available under the name Gaozaban, which has antibacterial, antifungal, anti-inflammatory, and wound-healing properties. In the present study, in vitro antioxidant and anticancer activity of different extracts of Arnebia benthamii were investigated. Antioxidant potential of plant extracts was evaluated by means of total phenolics, DPPH, reducing power, microsomal lipid peroxidation, and hydroxyl radical scavenging activity. The highest phenolic content (TPC of 780 mg GAE/g was observed in ethyl acetate, while the lowest TPC of 462 mg GAE/g was achieved in aqueous extract. At concentration of 700 µg/mL, DPPH radical scavenging activity was found to be highest in ethyl acetate extract (87.99% and lowest in aqueous extract (73%. The reducing power of extracts increased in a concentration dependent manner. We also observed its inhibition on Fe2+/ascorbic acid-induced lipid peroxidation (LPO on rat liver microsomes in vitro. In addition, Arnebia benthamii extracts exhibited antioxidant effects on Calf thymus DNA damage induced by Fenton reaction. Cytotoxicity of the extracts (10–100 µg/mL was tested on five human cancer cell lines (lung, prostate, leukemia, colon, and pancreatic cell lines using the Sulphorhodamine B assay.