WorldWideScience

Sample records for harness test based

  1. Developing a TTCN-3 Test Harness for Legacy Software

    DEFF Research Database (Denmark)

    Okika, Joseph C.; Ravn, Anders Peter; Siddalingaiah, Lokesh

    2006-01-01

    We describe a prototype test harness for an embedded system which is the control software for a modern marine diesel engine. The operations of such control software requires complete certification. We adopt Testing and Test Control Notation (TTCN-3) to define test cases for this purpose. The main...... challenge in developing the test harness is to interface a generic test driver to the legacy software and provide a suitable interface for test engineers. The main contribution of this paper is a demonstration of a suitable design for such a test harness. It includes: a TTCN-3 test driver in C++, the legacy...... control software in C, a Graphical User Interface (GUI) and the connectors in Java. Our experience shows that it is feasible to use TTCN-3 in developing a test harness for a legacy software for an embedded system, even when it involves different heterogeneous components....

  2. Harnessing the potential of Knowledge Based Engineering in manufacturing design

    NARCIS (Netherlands)

    Van den Berg, T.

    2013-01-01

    An increase in productivity is required for the European aviation industry to remain competitive in a world with rising competition, shorter development timescales, more complex products and decreasing numbers of technically skilled personnel. Fokker Elmo, a Dutch aircraft electrical wiring harness

  3. Harnessing scientific literature reports for pharmacovigilance. Prototype software analytical tool development and usability testing.

    Science.gov (United States)

    Sorbello, Alfred; Ripple, Anna; Tonning, Joseph; Munoz, Monica; Hasan, Rashedul; Ly, Thomas; Francis, Henry; Bodenreider, Olivier

    2017-03-22

    We seek to develop a prototype software analytical tool to augment FDA regulatory reviewers' capacity to harness scientific literature reports in PubMed/MEDLINE for pharmacovigilance and adverse drug event (ADE) safety signal detection. We also aim to gather feedback through usability testing to assess design, performance, and user satisfaction with the tool. A prototype, open source, web-based, software analytical tool generated statistical disproportionality data mining signal scores and dynamic visual analytics for ADE safety signal detection and management. We leveraged Medical Subject Heading (MeSH) indexing terms assigned to published citations in PubMed/MEDLINE to generate candidate drug-adverse event pairs for quantitative data mining. Six FDA regulatory reviewers participated in usability testing by employing the tool as part of their ongoing real-life pharmacovigilance activities to provide subjective feedback on its practical impact, added value, and fitness for use. All usability test participants cited the tool's ease of learning, ease of use, and generation of quantitative ADE safety signals, some of which corresponded to known established adverse drug reactions. Potential concerns included the comparability of the tool's automated literature search relative to a manual 'all fields' PubMed search, missing drugs and adverse event terms, interpretation of signal scores, and integration with existing computer-based analytical tools. Usability testing demonstrated that this novel tool can automate the detection of ADE safety signals from published literature reports. Various mitigation strategies are described to foster improvements in design, productivity, and end user satisfaction.

  4. Determining Damping Trends from a Range of Cable Harness Assemblies on a Launch Vehicle Panel from Test Measurements

    Science.gov (United States)

    Smith, Andrew; Davis, R. Ben; LaVerde, Bruce; Jones, Douglas

    2012-01-01

    The team of authors at Marshall Space Flight Center (MSFC) has been investigating estimating techniques for the vibration response of launch vehicle panels excited by acoustics and/or aero-fluctuating pressures. Validation of the approaches used to estimate these environments based on ground tests of flight like hardware is of major importance to new vehicle programs. The team at MSFC has recently expanded upon the first series of ground test cases completed in December 2010. The follow on tests recently completed are intended to illustrate differences in damping that might be expected when cable harnesses are added to the configurations under test. This validation study examines the effect on vibroacoustic response resulting from the installation of cable bundles on a curved orthogrid panel. Of interest is the level of damping provided by the installation of the cable bundles and whether this damping could be potentially leveraged in launch vehicle design. The results of this test are compared with baseline acoustic response tests without cables. Damping estimates from the measured response data are made using a new software tool that employs a finite element model (FEM) of the panel in conjunction with advanced optimization techniques. This paper will report on the \\damping trend differences. observed from response measurements for several different configurations of cable harnesses. The data should assist vibroacoustics engineers to make more informed damping assumptions when calculating vibration response estimates when using model based analysis approach. Achieving conservative estimates that have more flight like accuracy is desired. The paper may also assist analysts in determining how ground test data may relate to expected flight response levels. Empirical response estimates may also need to be adjusted if the measured response used as an input to the study came from a test article without flight like cable harnesses.

  5. A Reliable and Valid Objective Structured Assessment of Technical Skill for the Application of a Pavlik Harness Based on International Expert Consensus.

    Science.gov (United States)

    Bradley, Catharine S; Moktar, Joel; Maxwell, Alexandra; Wedge, John H; Murnaghan, Michael L; Kelley, Simon P

    2016-01-01

    The use of competency-based training is increasing in medical education as it offers individualized learning opportunities to master required skills. Inherent to this method of teaching is the need for standardized and objective assessments of skill mastery. In orthopaedic surgery, educational programs have focused on surgical skills with lesser emphasis on nonoperative techniques. Accordingly, formal evaluation tools specific to Pavlik Harness application do not exist, despite its widespread use and potential complications from inappropriate application. This study sought to develop a reliable and valid evaluation tool based on international expert consensus to standardize and evaluate Pavlik Harness application for developmental dysplasia of the hip. Consensus was sought from 10 content experts using Delphi methodology. Resulting items formed the Objective Structured Assessment of Technical Skill (OSATS). Thirty-five participants were selected into 3 a priori groups (expert, intermediate and novice) based on Pavlik Harness experience. On 2 occasions, 3 content experts assessed randomized and deidentified videotapes of each participant applying a Pavlik Harness to an infant model using the OSATS and global rating scales (GRS). The reliability and validity of the OSATS was determined with intraclass (ICC) and Pearson correlations and analysis of variance (ANOVA). Consensus was obtained after 2 rounds of structured surveying and resulted in a 25-item OSATS. The reliability of the OSATS was excellent with an ICC of 0.96 for interrater and 0.98 for test-retest reliability. Construct validity was excellent with high correlations between OSATS and GRS (>0.90). In addition, the OSATS discriminated between expert, intermediate, and novice users. We have developed a competency-based evaluation tool for Pavlik Harness application based on consensus from international experts. The OSATS has been shown to be a reliable and valid method for assessing Pavlik Harness application

  6. Research on the Statistical Characteristics of Crosstalk in Naval Ships Wiring Harness Based on Polynomial Chaos Expansion Method

    Directory of Open Access Journals (Sweden)

    Chi Yaodan

    2017-08-01

    Full Text Available Crosstalk in wiring harness has been studied extensively for its importance in the naval ships electromagnetic compatibility field. An effective and high-efficiency method is proposed in this paper for analyzing Statistical Characteristics of crosstalk in wiring harness with random variation of position based on Polynomial Chaos Expansion (PCE. A typical 14-cable wiring harness was simulated as the object of research. Distance among interfering cable, affected cable and GND is synthesized and analyzed in both frequency domain and time domain. The model of naval ships wiring harness distribution parameter was established by utilizing Legendre orthogonal polynomials as basis functions along with prediction model of statistical characters. Detailed mean value, mean square error, probability density function and reasonable varying range of crosstalk in naval ships wiring harness are described in both time domain and frequency domain. Numerical experiment proves that the method proposed in this paper, not only has good consistency with the MC method can be applied in the naval ships EMC research field to provide theoretical support for guaranteeing safety, but also has better time-efficiency than the MC method. Therefore, the Polynomial Chaos Expansion method.

  7. Harnessing Sun’s Energy with Quantum Dots Based Next Generation Solar Cell

    Science.gov (United States)

    Halim, Mohammad A.

    2012-01-01

    Our energy consumption relies heavily on the three components of fossil fuels (oil, natural gas and coal) and nearly 83% of our current energy is consumed from those sources. The use of fossil fuels, however, has been viewed as a major environmental threat because of their substantial contribution to greenhouse gases which are responsible for increasing the global average temperature. Last four decades, scientists have been searching for alternative sources of energy which need to be environmentally clean, efficient, cost-effective, renewable, and sustainable. One of the promising sustainable sources of energy can be achieved by harnessing sun energy through silicon wafer, organic polymer, inorganic dye, and quantum dots based solar cells. Among them, quantum dots have an exceptional property in that they can excite multiple electrons using only one photon. These dots can easily be synthesized, processed in solution, and incorporated into solar cell application. Interestingly, the quantum dots solar cells can exceed the Shockley-Queisser limit; however, it is a great challenge for other solar cell materials to exceed the limit. Theoretically, the quantum dots solar cell can boost the power conversion efficiency up to 66% and even higher to 80%. Moreover, in changing the size of the quantum dots one can utilize the Sun’s broad spectrum of visible and infrared ranges. This review briefly overviews the present performance of different materials-based solar cells including silicon wafer, dye-sensitized, and organic solar cells. In addition, recent advances of the quantum dots based solar cells which utilize cadmium sulfide/selenide, lead sulfide/selenide, and new carbon dots as light harvesting materials has been reviewed. A future outlook is sketched as to how one could improve the efficiency up to 10% from the current highest efficiency of 6.6%. PMID:28348320

  8. Harnessing Sun's Energy with Quantum Dots Based Next Generation Solar Cell.

    Science.gov (United States)

    Halim, Mohammad A

    2012-12-27

    Our energy consumption relies heavily on the three components of fossil fuels (oil, natural gas and coal) and nearly 83% of our current energy is consumed from those sources. The use of fossil fuels, however, has been viewed as a major environmental threat because of their substantial contribution to greenhouse gases which are responsible for increasing the global average temperature. Last four decades, scientists have been searching for alternative sources of energy which need to be environmentally clean, efficient, cost-effective, renewable, and sustainable. One of the promising sustainable sources of energy can be achieved by harnessing sun energy through silicon wafer, organic polymer, inorganic dye, and quantum dots based solar cells. Among them, quantum dots have an exceptional property in that they can excite multiple electrons using only one photon. These dots can easily be synthesized, processed in solution, and incorporated into solar cell application. Interestingly, the quantum dots solar cells can exceed the Shockley-Queisser limit; however, it is a great challenge for other solar cell materials to exceed the limit. Theoretically, the quantum dots solar cell can boost the power conversion efficiency up to 66% and even higher to 80%. Moreover, in changing the size of the quantum dots one can utilize the Sun's broad spectrum of visible and infrared ranges. This review briefly overviews the present performance of different materials-based solar cells including silicon wafer, dye-sensitized, and organic solar cells. In addition, recent advances of the quantum dots based solar cells which utilize cadmium sulfide/selenide, lead sulfide/selenide, and new carbon dots as light harvesting materials has been reviewed. A future outlook is sketched as to how one could improve the efficiency up to 10% from the current highest efficiency of 6.6%.

  9. Harnessing Sun’s Energy with Quantum Dots Based Next Generation Solar Cell

    Directory of Open Access Journals (Sweden)

    Mohammad A. Halim

    2012-12-01

    Full Text Available Our energy consumption relies heavily on the three components of fossil fuels (oil, natural gas and coal and nearly 83% of our current energy is consumed from those sources. The use of fossil fuels, however, has been viewed as a major environmental threat because of their substantial contribution to greenhouse gases which are responsible for increasing the global average temperature. Last four decades, scientists have been searching for alternative sources of energy which need to be environmentally clean, efficient, cost-effective, renewable, and sustainable. One of the promising sustainable sources of energy can be achieved by harnessing sun energy through silicon wafer, organic polymer, inorganic dye, and quantum dots based solar cells. Among them, quantum dots have an exceptional property in that they can excite multiple electrons using only one photon. These dots can easily be synthesized, processed in solution, and incorporated into solar cell application. Interestingly, the quantum dots solar cells can exceed the Shockley-Queisser limit; however, it is a great challenge for other solar cell materials to exceed the limit. Theoretically, the quantum dots solar cell can boost the power conversion efficiency up to 66% and even higher to 80%. Moreover, in changing the size of the quantum dots one can utilize the Sun’s broad spectrum of visible and infrared ranges. This review briefly overviews the present performance of different materials-based solar cells including silicon wafer, dye-sensitized, and organic solar cells. In addition, recent advances of the quantum dots based solar cells which utilize cadmium sulfide/selenide, lead sulfide/selenide, and new carbon dots as light harvesting materials has been reviewed. A future outlook is sketched as to how one could improve the efficiency up to 10% from the current highest efficiency of 6.6%.

  10. Harnessing Information Technology to Inform Patients Facing Routine Decisions: Cancer Screening as a Test Case.

    Science.gov (United States)

    Krist, Alex H; Woolf, Steven H; Hochheimer, Camille; Sabo, Roy T; Kashiri, Paulette; Jones, Resa M; Lafata, Jennifer Elston; Etz, Rebecca S; Tu, Shin-Ping

    2017-05-01

    Technology could transform routine decision making by anticipating patients' information needs, assessing where patients are with decisions and preferences, personalizing educational experiences, facilitating patient-clinician information exchange, and supporting follow-up. This study evaluated whether patients and clinicians will use such a decision module and its impact on care, using 3 cancer screening decisions as test cases. Twelve practices with 55,453 patients using a patient portal participated in this prospective observational cohort study. Participation was open to patients who might face a cancer screening decision: women aged 40 to 49 who had not had a mammogram in 2 years, men aged 55 to 69 who had not had a prostate-specific antigen test in 2 years, and adults aged 50 to 74 overdue for colorectal cancer screening. Data sources included module responses, electronic health record data, and a postencounter survey. In 1 year, one-fifth of the portal users (11,458 patients) faced a potential cancer screening decision. Among these patients, 20.6% started and 7.9% completed the decision module. Fully 47.2% of module completers shared responses with their clinician. After their next office visit, 57.8% of those surveyed thought their clinician had seen their responses, and many reported the module made their appointment more productive (40.7%), helped engage them in the decision (47.7%), broadened their knowledge (48.1%), and improved communication (37.5%). Many patients face decisions that can be anticipated and proactively facilitated through technology. Although use of technology has the potential to make visits more efficient and effective, cultural, workflow, and technical changes are needed before it could be widely disseminated. © 2017 Annals of Family Medicine, Inc.

  11. +CLICK: harnessing web-based training to reduce secondary transmission among HIV-positive youth.

    Science.gov (United States)

    Markham, Christine Margaret; Shegog, Ross; Leonard, Amy Dolph; Bui, Thanh C; Paul, Mary E

    2009-05-01

    Adolescents and young adults account for over 10 million HIV infections worldwide. Prevention of secondary transmission is a major concern as many HIV-positive youth continue to engage in risky sexual behavior. This study pilot-tested " + CLICK", an innovative, web-based, sexual risk reduction intervention for HIV-positive youth as an adjunct to traditional clinic-based, self-management education. The theory-based application, developed for perinatally and behaviorally infected youth 13-24 years of age, provides tailored activities addressing attitudes, knowledge, skills, and self-efficacy related to sexual risk reduction. HIV-positive youth (N=32) pilot-tested " + CLICK" to assess usability (ease of use, credibility, understandability, acceptability, motivation) and short-term psychosocial outcomes (importance and self-efficacy related to abstinence and condom use) using a single group, pre-/post-test study design in a hospital-based pediatric clinic and community locations. A subsample of participants (n=20) assessed feasibility for clinic use. Participants were 62.5% female, 68.8% Black, and 28.1% Hispanic. Mean age was 17.8 years (SD = 2.55), 43.8% were infected behaviorally, 56.2% perinatally, and 68.8% were sexually experienced. Usability ratings were high: 84.4% rated the application very easy to use; 93.8% perceived content as trustworthy; 87.5% agreed most words were understandable; 87.5% would use the application again. Short-term psychosocial outcomes indicate a significant increase in condom use self-efficacy (p=0.008) and positive trends toward importance (p=0.067) and self-efficacy (p=0.071) for waiting before having sex. Regarding feasibility, participants accessed " + CLICK" during waiting periods (average time, 15 minutes) in their routine clinic visit. Clinic staff rated " + CLICK" highly in providing consistent, confidential, and motivational sexual health education without significant disruption to clinic flow. Results suggest that the

  12. Upgrading Wood-Based Industries: Harnessing the Social Network of Small-Scale Furniture Producers and Their Institutions

    Directory of Open Access Journals (Sweden)

    Melati ,

    2011-05-01

    Full Text Available Furniture is a major export commodity in Indonesia with a total value of USD 1.96 million in 2007.  Jepara District is one of the key location for wood furniture production with 15,271 furniture related business units employing 176,469 workers.  However, inefficiencies and power imbalances throughout the furniture value chain have resulted in overharvesting and uneven distribution of gains among the industry’s actors.  In contrast to price-setting international furniture retailers, small-scale producers enjoy the least value from their products.  In order to increase added value and competitiveness, small-scale furniture producers have made efforts to upgrade by harnessing their social network and institutions.  This paper describes small-scale furniture producers’ efforts to upgrade by utilising their social network and institutions in Jepara.  Data was collected through in-depth interviews with members of the small-scale furniture producers’ association.  The research provides insight into the nature of social networks and information flow and develops future scenarios to upgrade.  The scenarios will not only benefit the furniture industry in Jepara, but may also be adopted for similar industries throughout Indonesia and the world, and potentially improve many people’s economies and livelihoods.Keywords: wood-based industry, furniture, small-scale, social network, institution

  13. Harnessing RNAi-based nanomedicines for therapeutic gene silencing in B-cell malignancies

    Science.gov (United States)

    Weinstein, Shiri; Toker, Itai A.; Emmanuel, Rafi; Ramishetti, Srinivas; Hazan-Halevy, Inbal; Rosenblum, Daniel; Goldsmith, Meir; Abraham, Avigdor; Benjamini, Ohad; Bairey, Osnat; Raanani, Pia; Nagler, Arnon; Lieberman, Judy

    2016-01-01

    Despite progress in systemic small interfering RNA (siRNA) delivery to the liver and to solid tumors, systemic siRNA delivery to leukocytes remains challenging. The ability to silence gene expression in leukocytes has great potential for identifying drug targets and for RNAi-based therapy for leukocyte diseases. However, both normal and malignant leukocytes are among the most difficult targets for siRNA delivery as they are resistant to conventional transfection reagents and are dispersed in the body. We used mantle cell lymphoma (MCL) as a prototypic blood cancer for validating a novel siRNA delivery strategy. MCL is an aggressive B-cell lymphoma that overexpresses cyclin D1 with relatively poor prognosis. Down-regulation of cyclin D1 using RNA interference (RNAi) is a potential therapeutic approach to this malignancy. Here, we designed lipid-based nanoparticles (LNPs) coated with anti-CD38 monoclonal antibodies that are specifically taken up by human MCL cells in the bone marrow of xenografted mice. When loaded with siRNAs against cyclin D1, CD38-targeted LNPs induced gene silencing in MCL cells and prolonged survival of tumor-bearing mice with no observed adverse effects. These results highlight the therapeutic potential of cyclin D1 therapy in MCL and present a novel RNAi delivery system that opens new therapeutic opportunities for treating MCL and other B-cell malignancies. PMID:26699502

  14. Harnessing temporal modes for multi-photon quantum information processing based on integrated optics.

    Science.gov (United States)

    Harder, G; Ansari, V; Bartley, T J; Brecht, B; Silberhorn, C

    2017-08-06

    In the last few decades, there has been much progress on low loss waveguides, very efficient photon-number detectors and nonlinear processes. Engineered sum-frequency conversion is now at a stage where it allows operation on arbitrary temporal broadband modes, thus making the spectral degree of freedom accessible for information coding. Hereby the information is often encoded into the temporal modes of a single photon. Here, we analyse the prospect of using multi-photon states or squeezed states in different temporal modes based on integrated optics devices. We describe an analogy between mode-selective sum-frequency conversion and a network of spatial beam splitters. Furthermore, we analyse the limits on the achievable squeezing in waveguides with current technology and the loss limits in the conversion process.This article is part of the themed issue 'Quantum technology for the 21st century'. © 2017 The Author(s).

  15. HARNESSING INNOVATION POTENTIAL OF CROWDSOURCING

    OpenAIRE

    Slavica ROCHESKA; Marjan ANGELESKI; Dimitar NIKOLOSKI; Gjorgji MANCHESKI

    2014-01-01

    The new innovation paradigm is based upon articulation of external and internal sources of innovation. Nowadays, crowdsourcing is coming up as significant external source in innovation processes of the companies. Crowdsourcing enables harnessing of initiatives, ideas, solutions and knowledge of the crowd so as to enhance innovation performance and induce a value creation. Given that existing innovation literature does not cover sufficiently the issues related to crowdsourcing this paper is to...

  16. Behavior of sandhill cranes harnessed with different satellite transmitters

    Science.gov (United States)

    Olsen, Glenn H.; Ellis, D.H.; Landfried, S.E.; Miller, L.H.; Klugman, S.S.; Fuller, M.R.; Vermillion, C.H.

    1992-01-01

    The effectiveness of various attachment methods and designs of platform transmitting terminals (PTT's) was tested on captive sandhill cranes (Grus canadensis) at the Patuxent Wildlife Research Center, Laurel, Maryland, during 1989-91. Combinations of attachment and transmitter designs included neoprene cord harness with batteries separate from the transmitter (2 harness designs), Teflon ribbon harness with batteries incorporated into the transmitter package (4 transmitter models), and a package attached directly to the bird with epoxy glue only. Physical effects seen on cranes wearing PTT's ranged from skin lacerations (caused by rubbing of harness material) to no observed effects (other than feather wear). The most successful harness material and design utilized a Teflon ribbon harness with the 4 ribbon ends from the transmitter forming a neck loop and a body loop joined at the sternum. Time spent by sandhill cranes performing most activities did not change after transmitter attachment using this harness method.

  17. Kumar, Prof. Har Darshan

    Indian Academy of Sciences (India)

    Fellow Profile. Elected: 1975 Section: Plant Sciences. Kumar, Prof. Har Darshan Ph.D. (London), FNA, FNASc. Date of birth: 25 February 1934. Specialization: Algology, Microbial Biotechnology, Genetics, Ecology and Environment Address: Mrigtrishna, B.32/32, H.K. 214, Saketnagar Colony, Naria, Varanasi 221 005, U.P.

  18. Har Gobind Khorana

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 17; Issue 12. Har Gobind Khorana - Early Years in Science and Transition from Chemistry to Chemical Biology. Uttam L Rajbhandary. General Article Volume 17 Issue 12 December 2012 pp 1125-1135 ...

  19. Khorana, Prof. Har Gobind

    Indian Academy of Sciences (India)

    Elected: 1976 Honorary. Khorana, Prof. Har Gobind Nobel Laureate (Medicine) - 1968. Date of birth: 9 January 1922. Date of death: 9 November 2011. Last known address: Alfred P. Sloan Professor of, Biology and Chemistry, Massachusetts Institute of, Technology, 77 Massachusetts Ave., Cambridge, MA 02139, U.S.A..

  20. Dine marker har DNA

    DEFF Research Database (Denmark)

    Eckholdt, Annette; Winding, Anne; Krogh, Paul Henning

    2017-01-01

    Ordet "biodiversitet" og at det er noget, vi skal have mere af, nævnes hyppigt. Men hvad er biodiversitet, og hvordan måles det? Agrologisk har bedt et par eksperter fra Aarhus Universitet forklare, hvordan et DNA-aftryk af jord og vand kan erstatte optællinger i felten og sige noget om biodivers......Ordet "biodiversitet" og at det er noget, vi skal have mere af, nævnes hyppigt. Men hvad er biodiversitet, og hvordan måles det? Agrologisk har bedt et par eksperter fra Aarhus Universitet forklare, hvordan et DNA-aftryk af jord og vand kan erstatte optællinger i felten og sige noget om...

  1. Harnessing solar heat

    CERN Document Server

    Norton, Brian

    2013-01-01

    Systems engineered by man to harness solar heat in a controlled manner now include a diverse range of technologies each serving distinctive needs in particular climate contexts. This text covers the breadth of solar energy technologies for the conversion of solar energy to provide heat, either as the directly-used output or as an intermediary to other uses such as power generation or cooling. It is a wholly updated, extended and revised version of “Solar Energy Thermal Technology” first published in 1992. The text draws on the own author’s research and that of numerous colleagues and

  2. Model-Based Testing

    NARCIS (Netherlands)

    Timmer, Mark; Brinksma, Hendrik; Stoelinga, Mariëlle Ida Antoinette; Broy, M.; Leuxner, C.; Hoare, C.A.R.

    This paper provides a comprehensive introduction to a framework for formal testing using labelled transition systems, based on an extension and reformulation of the ioco theory introduced by Tretmans. We introduce the underlying models needed to specify the requirements, and formalise the notion of

  3. Harnessing our very life.

    Science.gov (United States)

    Wills, Peter R; Williams, David L F; Trussell, Denys; Mann, L R B

    2013-01-01

    The Aristotelian ideas of nature (physis) and technology (techné) are taken as a starting point for understanding what it would mean for technology to be truly living. Heidegger's critique of the conflation of scientific and technological thinking in the current era is accepted as demonstrating that humanity does not have a deep enough appreciation of the nature of life to harness its essence safely. Could the vision of harnessing life be realized, which we strongly doubt, living technology would give selected humans transforming powers that could be expected to exacerbate, rather than solve, current global problems. The source of human purposefulness, and hence of both technology and ethics, is identified in nature's emergent capability to instantiate informational representations in material forms. Ethics that are properly grounded in an appreciation of intrinsic value, especially that of life, demand that proposals to give humanity the capabilities of living technology address the social, political, economic, and environmental problems inherent in its development and potential deployment. Before any development is embarked on, steps must be taken to avoid living technology, whatever the term eventually designates, becoming available for destructive or antisocial purposes such as those that might devastate humanity or irrevocably damage the natural world.

  4. Design Process Improvement for Electric CAR Harness

    Science.gov (United States)

    Sawatdee, Thiwarat; Chutima, Parames

    2017-06-01

    In an automobile parts design company, the customer satisfaction is one of the most important factors for product design. Therefore, the company employs all means to focus its product design process based on the various requirements of customers resulting in high number of design changes. The objective of this research is to improve the design process of the electric car harness that effects the production scheduling by using Fault Tree Analysis (FTA) and Failure Mode and Effect Analysis (FMEA) as the main tools. FTA is employed for root cause analysis and FMEA is used to ranking a High Risk Priority Number (RPN) which is shows the priority of factors in the electric car harness that have high impact to the design of the electric car harness. After the implementation, the improvements are realized significantly since the number of design change is reduced from 0.26% to 0.08%.

  5. HARNESSING BIG DATA VOLUMES

    Directory of Open Access Journals (Sweden)

    Bogdan DINU

    2014-04-01

    Full Text Available Big Data can revolutionize humanity. Hidden within the huge amounts and variety of the data we are creating we may find information, facts, social insights and benchmarks that were once virtually impossible to find or were simply inexistent. Large volumes of data allow organizations to tap in real time the full potential of all the internal or external information they possess. Big data calls for quick decisions and innovative ways to assist customers and the society as a whole. Big data platforms and product portfolio will help customers harness to the full the value of big data volumes. This paper deals with technical and technological issues related to handling big data volumes in the Big Data environment.

  6. A KBE Application for Automatic Aircraft Wire Harness Routing

    NARCIS (Netherlands)

    Zhu, Z.; Van Tooren, M.J.L.; La Rocca, G.

    2012-01-01

    Wire harness design is an increasingly complex task. Knowledge Based Engineering (KBE) and optimization techniques can be used to support designers in handling this complexity. The wire harness design process can be divided in three main parts, namely electrical design, configuration design and

  7. HARNESSING INNOVATION POTENTIAL OF CROWDSOURCING

    Directory of Open Access Journals (Sweden)

    Slavica ROCHESKA

    2014-05-01

    Full Text Available The new innovation paradigm is based upon articulation of external and internal sources of innovation. Nowadays, crowdsourcing is coming up as significant external source in innovation processes of the companies. Crowdsourcing enables harnessing of initiatives, ideas, solutions and knowledge of the crowd so as to enhance innovation performance and induce a value creation. Given that existing innovation literature does not cover sufficiently the issues related to crowdsourcing this paper is to offer an additional views about innovation potentials of crowdsourcing thus contributing for future research on this relatively unexplored concept. Therefore, this paper aims at considering key insights about crowdsourcing contribution on developing companies’ innovation capacity. More specifically it is focused on identification of benefits, weaknesses and risks arising from crowdsourcing to the innovation process comprising conceptual and empirical aspects.

  8. Compositional based testing with ioco

    NARCIS (Netherlands)

    van der Bijl, H.M.; Rensink, Arend; Tretmans, G.J.; Petrenko, A.; Ulrich, A.

    2004-01-01

    Compositional testing concerns the testing of systems that consist of communicating components which can also be tested in isolation. Examples are component based testing and interoperability testing. We show that, with certain restrictions, the ioco-test theory for conformance testing is suitable

  9. Building a bio-based industry in the Middle East through harnessing the potential of the Red Sea biodiversity

    DEFF Research Database (Denmark)

    Nielsen, Jens; Archer, John; Essack, Magbubah

    2017-01-01

    The incentive for developing microbial cell factories for production of fuels and chemicals comes from the ability of microbes to deliver these valuable compounds at a reduced cost and with a smaller environmental impact compared to the analogous chemical synthesis. Another crucial advantage...... of microbes is their great biological diversity, which offers a much larger “catalog” of molecules than the one obtainable by chemical synthesis. Adaptation to different environments is one of the important drives behind microbial diversity. We argue that the Red Sea, which is a rather unique marine niche......, represents a remarkable source of biodiversity that can be geared towards economical and sustainable bioproduction processes in the local area and can be competitive in the international bio-based economy. Recent bioprospecting studies, conducted by the King Abdullah University of Science and Technology...

  10. Building a bio-based industry in the Middle East through harnessing the potential of the Red Sea biodiversity

    KAUST Repository

    Nielsen, Jens

    2017-05-20

    The incentive for developing microbial cell factories for production of fuels and chemicals comes from the ability of microbes to deliver these valuable compounds at a reduced cost and with a smaller environmental impact compared to the analogous chemical synthesis. Another crucial advantage of microbes is their great biological diversity, which offers a much larger “catalog” of molecules than the one obtainable by chemical synthesis. Adaptation to different environments is one of the important drives behind microbial diversity. We argue that the Red Sea, which is a rather unique marine niche, represents a remarkable source of biodiversity that can be geared towards economical and sustainable bioproduction processes in the local area and can be competitive in the international bio-based economy. Recent bioprospecting studies, conducted by the King Abdullah University of Science and Technology, have established important leads on the Red Sea biological potential, with newly isolated strains of Bacilli and Cyanobacteria. We argue that these two groups of local organisms are currently most promising in terms of developing cell factories, due to their ability to operate in saline conditions, thus reducing the cost of desalination and sterilization. The ability of Cyanobacteria to perform photosynthesis can be fully exploited in this particular environment with one of the highest levels of irradiation on the planet. We highlight the importance of new experimental and in silico methodologies needed to overcome the hurdles of developing efficient cell factories from the Red Sea isolates.

  11. Building a bio-based industry in the Middle East through harnessing the potential of the Red Sea biodiversity.

    Science.gov (United States)

    Nielsen, Jens; Archer, John; Essack, Magbubah; Bajic, Vladimir B; Gojobori, Takashi; Mijakovic, Ivan

    2017-06-01

    The incentive for developing microbial cell factories for production of fuels and chemicals comes from the ability of microbes to deliver these valuable compounds at a reduced cost and with a smaller environmental impact compared to the analogous chemical synthesis. Another crucial advantage of microbes is their great biological diversity, which offers a much larger "catalog" of molecules than the one obtainable by chemical synthesis. Adaptation to different environments is one of the important drives behind microbial diversity. We argue that the Red Sea, which is a rather unique marine niche, represents a remarkable source of biodiversity that can be geared towards economical and sustainable bioproduction processes in the local area and can be competitive in the international bio-based economy. Recent bioprospecting studies, conducted by the King Abdullah University of Science and Technology, have established important leads on the Red Sea biological potential, with newly isolated strains of Bacilli and Cyanobacteria. We argue that these two groups of local organisms are currently most promising in terms of developing cell factories, due to their ability to operate in saline conditions, thus reducing the cost of desalination and sterilization. The ability of Cyanobacteria to perform photosynthesis can be fully exploited in this particular environment with one of the highest levels of irradiation on the planet. We highlight the importance of new experimental and in silico methodologies needed to overcome the hurdles of developing efficient cell factories from the Red Sea isolates.

  12. Targeting Rapamycin to Podocytes Using a Vascular Cell Adhesion Molecule-1 (VCAM-1-Harnessed SAINT-Based Lipid Carrier System.

    Directory of Open Access Journals (Sweden)

    Ganesh Ram R Visweswaran

    Full Text Available Together with mesangial cells, glomerular endothelial cells and the basement membrane, podocytes constitute the glomerular filtration barrier (GFB of the kidney. Podocytes play a pivotal role in the progression of various kidney-related diseases such as glomerular sclerosis and glomerulonephritis that finally lead to chronic end-stage renal disease. During podocytopathies, the slit-diaphragm connecting the adjacent podocytes are detached leading to severe loss of proteins in the urine. The pathophysiology of podocytopathies makes podocytes a potential and challenging target for nanomedicine development, though there is a lack of known molecular targets for cell selective drug delivery. To identify VCAM-1 as a cell-surface receptor that is suitable for binding and internalization of nanomedicine carrier systems by podocytes, we investigated its expression in the immortalized podocyte cell lines AB8/13 and MPC-5, and in primary podocytes. Gene and protein expression analyses revealed that VCAM-1 expression is increased by podocytes upon TNFα-activation for up to 24 h. This was paralleled by anti-VCAM-1 antibody binding to the TNFα-activated cells, which can be employed as a ligand to facilitate the uptake of nanocarriers under inflammatory conditions. Hence, we next explored the possibilities of using VCAM-1 as a cell-surface receptor to deliver the potent immunosuppressant rapamycin to TNFα-activated podocytes using the lipid-based nanocarrier system Saint-O-Somes. Anti-VCAM-1-rapamycin-SAINT-O-Somes more effectively inhibited the cell migration of AB8/13 cells than free rapamycin and non-targeted rapamycin-SAINT-O-Somes indicating the potential of VCAM-1 targeted drug delivery to podocytes.

  13. Harnessing benefits of helping others: a randomized controlled trial testing expressive helping to address survivorship problems after hematopoietic stem cell transplant.

    Science.gov (United States)

    Rini, Christine; Austin, Jane; Wu, Lisa M; Winkel, Gary; Valdimarsdottir, Heiddis; Stanton, Annette L; Isola, Luis; Rowley, Scott; Redd, William H

    2014-12-01

    Prior research supports the hypothesis that cancer survivors who help others face treatment experience a range of psychosocial and health-related benefits as a result of peer helping. This study investigates an expressive helping (EH) intervention designed to harness those benefits by targeting survivorship problems among cancer survivors treated with hematopoietic stem cell transplant. EH includes two components: (a) emotionally expressive writing (EW; writing one's deepest thoughts and feelings about the transplant experience in a series of brief, structured writing sessions) followed by (b) peer helping (PH; helping other people prepare for transplant by sharing one's own transplant experiences along with advice and encouragement through a written narrative). EH was compared with neutral writing (NW), EW (without PH), and PH (without EW) in a 4-arm randomized controlled trial in which survivors completed baseline measures, 4 structured writing exercises (with instructions depending on randomization), and postintervention measures including validated measures of general psychological distress, physical symptoms, and health-related quality of life (HRQOL). Among survivors with moderate-severe survivorship problems, EH reduced distress (compared with NW and PH; ps writing benefits transplant survivors with moderate-severe survivorship problems, but only if they have first completed expressive writing.

  14. Ambulatory purchasing: harnessing supply costs.

    Science.gov (United States)

    Jager, P A

    1997-04-01

    The healthcare system remains in a dynamic state of flux. We have all heard the story: the changing healthcare market brings reduced reimbursement for services, increased competition, and steadily increasing supply, maintenance, and equipment costs. Ambulatory surgery centers (ASCs) must keep in sync with this change or fail to survive the current market forces. However, because they represent a small contract to various vendors, many ASCs pay premium prices for inventory while receiving less from Managed Care Plans (MCPs) and Health Maintenance Organizations (HMOs). This dilemma makes control of supply costs a top priority for ASCs. In reality, purchasing is becoming more strategically connected to the ASC balance sheet than ever before. Apart from personnel costs, supply and pharmaceutical purchasing represents the greatest expense category on our financial statement. Harnessing these costs directly relates to bottom line profitability. In addition, while performing cost savings magic, ASCs must maintain patient and surgeon satisfaction with the superior outcomes and state-of-the-art technology their reputations are based upon. Sound impossible? This article details how Surgery Center Plus, Inc. (SCP) implemented a cost containment project.

  15. Harnessing off-target effects

    DEFF Research Database (Denmark)

    Saginc, Gaye; Voellmy, Franziska; Linding, Rune

    2017-01-01

    The 'off-targets' of a drug are often poorly characterized yet could be harnessed in the treatment of complex diseases. A recent study used a small-molecule screening in non-small-cell lung cancer to repurpose an FDA-approved ALK/IGF1R inhibitor and uncover its mechanism of action.......The 'off-targets' of a drug are often poorly characterized yet could be harnessed in the treatment of complex diseases. A recent study used a small-molecule screening in non-small-cell lung cancer to repurpose an FDA-approved ALK/IGF1R inhibitor and uncover its mechanism of action....

  16. Har vi brug for hovedregning?

    DEFF Research Database (Denmark)

    Ejersbo, Lisser Rye

    2015-01-01

    Hvor ofte har vi brug for at regne noget i hoved? Har de fleste af os ikke altid et elektronisk hjælpemiddel ved hånden enten som en lille lommeregner eller telefonen? Selvom det umiddelbart kan synes unødvendigt at træne hovedregning, viser det sig, at netop træning af hovedregning støtter...... udvikling af hurtige regnestrategier, hvorfor det faktisk er en god ide at investere tid og energi i at træne netop dette....

  17. Flight performance, energetics and water turnover of tippler pigeons with a harness and dorsal load

    Science.gov (United States)

    Gessaman, J.A.; Workman, G.W.; Fuller, M.R.

    1991-01-01

    We measured carbon dioxide production and water efflux of 12 tippler pigeons (Columba spp.) during seven experimental flights using the doubly labeled water (DLW) method. Prior to the experiment birds were randomly assigned to one of two groups. One group flew as controls (no load or harness) on all seven flights. The other group wore a harness on two flights, a dorsal load/harness package (weighing about 5% of a bird's mass) on two flights, and they were without a load in three flights. Flight duration of pigeons with only a harness and with a dorsal load/harness package was 21 and 26% less, respectively, than the controls. Pigeons wearing a harness, or wearing a dorsal load/harness package lost water 50-90%, and 57-100% faster, respectively, than control pigeons. The mean CO2 production of pigeons wearing a harness or a load/harness package was not significantly different than pigeons without a harness or load. The small sample sizes and large variability in DLW measuremets precluded a good test of the energetic cost of flying with a harness and dorsal load.

  18. Flight performance energetics and water turnovers of Tippler Pigeons with a harness and doorsal load

    Science.gov (United States)

    Gessaman, James A.; Workman, Gar W.; Fuller, Mark R.

    1991-01-01

    We measured carbon dioxide production and water efflux of 12 tippler pigeons (Columba spp.) during seven experimental flights using the doubly labeled water (DLW) method. Prior to the experiment birds were randomly assigned to one of two groups. One group flew as controls (no load or harness) on all seven flights. The other group wore a harness on two flights, a dorsal load/harness package (weighing about 5% of a birda??s mass) on two flights, and they were without a load in three flights. Plight duration of pigeons with only a harness and with a dorsal load/harness package was 21 and 26% less, respectively, than the controls. Pigeons wearing a harness, or wearing a dorsal load/harness package lost water 50-90%, and 57-100% faster, respectively, than control pigeons. The mean CO, production of pigeons wearing a harness or a load/harness package was not significantly different than pigeons without a harness or load. The small sample sizes and large variability in DLW measurements precluded a good test of the energetic cost of flying with a harness and dorsal load.

  19. Harnessing Aquatic Physicochemical Parameters Influencing ...

    African Journals Online (AJOL)

    The management-oriented background for harnessing aquatic physicochemical parameters influencing macro invertebrate fauna of Anambra River basin for sustainable fish productivity was studied. The intra seasonal variability in the water quality of the river revealed mean transparency of 1.79 cm, Conductivity of 28.81 ...

  20. Model-Based Security Testing

    Directory of Open Access Journals (Sweden)

    Ina Schieferdecker

    2012-02-01

    Full Text Available Security testing aims at validating software system requirements related to security properties like confidentiality, integrity, authentication, authorization, availability, and non-repudiation. Although security testing techniques are available for many years, there has been little approaches that allow for specification of test cases at a higher level of abstraction, for enabling guidance on test identification and specification as well as for automated test generation. Model-based security testing (MBST is a relatively new field and especially dedicated to the systematic and efficient specification and documentation of security test objectives, security test cases and test suites, as well as to their automated or semi-automated generation. In particular, the combination of security modelling and test generation approaches is still a challenge in research and of high interest for industrial applications. MBST includes e.g. security functional testing, model-based fuzzing, risk- and threat-oriented testing, and the usage of security test patterns. This paper provides a survey on MBST techniques and the related models as well as samples of new methods and tools that are under development in the European ITEA2-project DIAMONDS.

  1. Alle har en historie, IV

    DEFF Research Database (Denmark)

    Ydegaard, Torbjørn

    Alle har en historie IV: Pædagogik med Freedom Writers lader et væld af pædagogiske facetter udspringe af den kendte skole-film Freedom Writers’ scener og handlinger. Der er både fokus på en almen tilgang til pædagogik og på Freedom Writer-metodikken, dels gennem de filmscener, der sættes til...

  2. Harnessing the Microbiome to Enhance Cancer Immunotherapy

    Directory of Open Access Journals (Sweden)

    Michelle H. Nelson

    2015-01-01

    Full Text Available The microbiota plays a key role in regulating the innate and adaptive immune system. Herein, we review the immunological aspects of the microbiota in tumor immunity in mice and man, with a focus on toll-like receptor (TLR agonists, vaccines, checkpoint modulators, chemotherapy, and adoptive T cell transfer (ACT therapies. We propose innovative treatments that may safely harness the microbiota to enhance T cell-based therapies in cancer patients. Finally, we highlight recent developments in tumor immunotherapy, particularly novel ways to modulate the microbiome and memory T cell responses to human malignancies.

  3. Har lægers risikovillighed og symptomer på udbrændthed betydning for brugen af PSA-tests?

    DEFF Research Database (Denmark)

    Pedersen, Anette Fischer; Carlsen, Anders Helles; Vedsted, Peter

    2016-01-01

    Denne artikel er baseret på undersøgelsen "Association of GP's risk attitudes, level of empathy, and burnout status with PSA testing in primary care, som er publiceret i British Journal of General Practice, December 2015; 65(44): 845-851......Denne artikel er baseret på undersøgelsen "Association of GP's risk attitudes, level of empathy, and burnout status with PSA testing in primary care, som er publiceret i British Journal of General Practice, December 2015; 65(44): 845-851...

  4. On-Orbit Evaluation of a New Treadmill Harness for Improved Crewmember Comfort and Load Distribution

    Science.gov (United States)

    Perusek, G. P.; Sheehan, C. C.; Savina, M. C.; Owings, T. M.; Davis, B. L.; Ryder, J. W.

    2011-01-01

    The current design of the International Space Station (ISS) Treadmill Harness has been reported to cause pain and discomfort to crewmembers during exercise. The Harness Station Development Test Objective (SDTO) provided participating crewmembers (n = 6) with a new harness design, the "Glenn Harness," to evaluate for comfort and loading as compared to the current Treadmill Harness. A novel suite of load-sensing instrumentation was developed to noninvasively measure load distribution and provided a first-ever quantification of actual dynamic loads during treadmill exercise. In addition, crew debriefs provided feedback on harness preference and overall impressions. Conclusions: Post-flight analysis in returned Glenn Harnesses (n = 3) showed minimal wear and tear. Four of the six subjects found the Glenn Harness to be more comfortable in this on-orbit, side-by-side comparison as measured by the crew comfort questionnaire and crew debriefs. Specific areas for improvement have been identified, and forward recommendations will be provided to the Human Research Program. The protocol developed for the SDTO provided valuable insight into crew comfort issues, design improvements, and loading preferences for exercise harnessing, which lays the groundwork for better harnessing systems and training protocols.

  5. Harness processes and harmonic crystals

    OpenAIRE

    Ferrari, Pablo A.; Niederhauser, Beat M.

    2003-01-01

    In the Hammersley harness processes the real-valued height at each site i in Z^d is updated at rate 1 to an average of the neighboring heights plus a centered random variable (the noise). We construct the process "a la Harris" simultaneously for all times and boxes contained in Z^d. With this representation we compute covariances and show L^2 and almost sure time and space convergence of the process. In particular, the process started from the flat configuration and viewed from the height at ...

  6. Risk Based Optimal Fatigue Testing

    DEFF Research Database (Denmark)

    Sørensen, John Dalsgaard; Faber, M.H.; Kroon, I.B.

    1992-01-01

    Optimal fatigue life testing of materials is considered. Based on minimization of the total expected costs of a mechanical component a strategy is suggested to determine the optimal stress range levels for which additional experiments are to be performed together with an optimal value of the maxi......Optimal fatigue life testing of materials is considered. Based on minimization of the total expected costs of a mechanical component a strategy is suggested to determine the optimal stress range levels for which additional experiments are to be performed together with an optimal value...

  7. Synthesis of Fluorescent Carbon Dots by Gastrointestinal Fluid Treatment of Mongolia Har Gabur

    Directory of Open Access Journals (Sweden)

    Tegexibaiyin Wang

    2017-01-01

    Full Text Available Har Gabur is the carbide obtained from pig manure by burning. The fluorescent carbon dots (CDs of Har Gabur were successfully synthesized through simulating the digestion process of human gastrointestinal tract. Transmission Electron Microscope (TEM analysis showed that the average size of the prepared Har Gabur CDs was 4 nm, with good solubility in water and strong fluorescence under UV irradiation. The X-ray and Raman results showed that the Har Gabur CDs were mainly composed of oxygen “O” and carbon “C” elements, in the forms of “C=O” and “C-O.” The bond energy results showed that the nitrogen “N” atom presented as “C-N” form, which indicated that Har Gabur CDs also contain “N.” In photobleaching assay, Har Gabur CDs showed excellent light stability compared with ordinary organic dye, fluorescein, and Rhodamine B. The fluorescence intensity of Har Gabur CDs was fairly stable within a wide pH range of 3–10. When L-lysine and L-cysteine were applied for the passivation stage, the relative quantum yields were improved by 1.53 and 3.68 times, respectively. Finally, the fluorescence properties of Har Gabur CDs were tested in cells and zebrafish, illustrating that Har Gabur CD has potential in the application of biological labeling and imaging.

  8. Discharging test of electric power harness

    OpenAIRE

    Kawakita, Shiro; Takahashi, Masato; Kusawake, Hiroaki; Kuwajima, Saburo; 川北 史朗; 高橋 真人; 艸分 宏晶; 桑島 三郎

    2004-01-01

    The mechanism of electric power failure of a satellite has been researched. There are many reasons of loss of electric power of a satellite. Investigated was the power loss due to the sustained arc between primary power cables. The heat though arc tracking between the hot and return cables by secondary are discharge made them burn out. If the phenomenon were occurred in space, the satellite would suffer great damage.

  9. Harnessing supramolecular peptide nanotechnology in biomedical applications.

    Science.gov (United States)

    Chan, Kiat Hwa; Lee, Wei Hao; Zhuo, Shuangmu; Ni, Ming

    2017-01-01

    The harnessing of peptides in biomedical applications is a recent hot topic. This arises mainly from the general biocompatibility of peptides, as well as from the ease of tunability of peptide structure to engineer desired properties. The ease of progression from laboratory testing to clinical trials is evident from the plethora of examples available. In this review, we compare and contrast how three distinct self-assembled peptide nanostructures possess different functions. We have 1) nanofibrils in biomaterials that can interact with cells, 2) nanoparticles that can traverse the bloodstream to deliver its payload and also be bioimaged, and 3) nanotubes that can serve as cross-membrane conduits and as a template for nanowire formation. Through this review, we aim to illustrate how various peptides, in their various self-assembled nanostructures, possess great promise in a wide range of biomedical applications and what more can be expected.

  10. Cell-Based Genotoxicity Testing

    Science.gov (United States)

    Reifferscheid, Georg; Buchinger, Sebastian

    Genotoxicity test systems that are based on bacteria display an important role in the detection and assessment of DNA damaging chemicals. They belong to the basic line of test systems due to their easy realization, rapidness, broad applicability, high sensitivity and good reproducibility. Since the development of the Salmonella microsomal mutagenicity assay by Ames and coworkers in the early 1970s, significant development in bacterial genotoxicity assays was achieved and is still a subject matter of research. The basic principle of the mutagenicity assay is a reversion of a growth inhibited bacterial strain, e.g., due to auxotrophy, back to a fast growing phenotype (regain of prototrophy). Deeper knowledge of the ­mutation events allows a mechanistic understanding of the induced DNA-damage by the utilization of base specific tester strains. Collections of such specific tester strains were extended by genetic engineering. Beside the reversion assays, test systems utilizing the bacterial SOS-response were invented. These methods are based on the fusion of various SOS-responsive promoters with a broad variety of reporter genes facilitating numerous methods of signal detection. A very important aspect of genotoxicity testing is the bioactivation of ­xenobiotics to DNA-damaging compounds. Most widely used is the extracellular metabolic activation by making use of rodent liver homogenates. Again, genetic engineering allows the construction of highly sophisticated bacterial tester strains with significantly enhanced sensitivity due to overexpression of enzymes that are involved in the metabolism of xenobiotics. This provides mechanistic insights into the toxification and detoxification pathways of xenobiotics and helps explaining the chemical nature of hazardous substances in unknown mixtures. In summary, beginning with "natural" tester strains the rational design of bacteria led to highly specific and sensitive tools for a rapid, reliable and cost effective

  11. Kvote 2 optagelse og akademiske præstationer: Hvor stor betydning har det adgangsgivende eksamenssnit?

    Directory of Open Access Journals (Sweden)

    Lotte Dyhrberg ONeill

    2013-03-01

    Full Text Available Kvote 2 optagelse (optagelsesprøver til medicinstudiet har vist sig at have virket beskyttende på tidligt studiefrafald sammenlignet med kvote 1 optagelse på Syddansk Universitet. Dette prospektive kohorte studie af de samme kohorter viser, at de lavere adgangsgivende karakterer i kvote 2 gruppen samtidigt kun var forbundet med lidt lavere bachelor karaktergennemsnit. Admission testing appears to be protective against early dropout compared to grade-based admission for undergraduate medical students at the University of Southern Denmark. This prospective cohort study shows that the lower entry grades of the admission tested students were simultaneously associated with obtaining only slightly lower medical school grades.

  12. Har du rådne kunder?

    DEFF Research Database (Denmark)

    Grünbaum, Niels Nolsøe

    2015-01-01

    Tætte kunderelationer er ikke altid guld værd. Har du modet til at skille dig af med kunder, som ødelægger din forretning?......Tætte kunderelationer er ikke altid guld værd. Har du modet til at skille dig af med kunder, som ødelægger din forretning?...

  13. 14 CFR 91.521 - Shoulder harness.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Shoulder harness. 91.521 Section 91.521 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR TRAFFIC... Airplanes and Fractional Ownership Program Aircraft § 91.521 Shoulder harness. (a) No person may operate a...

  14. A Key Review of Non-Industrial Greywater Heat Harnessing

    Directory of Open Access Journals (Sweden)

    Abdur Rehman Mazhar

    2018-02-01

    Full Text Available The ever-growing concerns about making buildings more energy efficient and increasing the share of renewable energy used in them, has led to the development of ultra-low carbon buildings or passive houses. However, a huge potential still exists to lower the hot water energy demand, especially by harnessing heat from waste water exiting these buildings. Reusing this heat makes buildings more energy-efficient and this source is considered as a third-generation renewable energy technology, both factors conforming to energy policies throughout the world. Based on several theoretical and experimental studies, the potential to harness non-industrial waste water is quite high. As an estimate about 3.5 kWh of energy, per person per day could be harnessed and used directly, in many applications. A promising example of such an application, are low temperature fourth generation District Heating grids, with decentralized sources of heat. At the moment, heat exchangers and heat pumps are the only viable options to harness non-industrial waste heat. Both are used at different scales and levels of the waste-water treatment hierarchical pyramid. Apart from several unfavourable characteristics of these technologies, the associated exergetic efficiencies are low, in the range of 20–50%, even when cascaded combinations of both are used. To tackle these shortcomings, several promising trends and technologies are in the pipeline, to scavenge this small-scale source of heat to a large-scale benefit.

  15. [Vascular thrombosis and pulmonary thrombo-embolism due to harness suspension].

    Science.gov (United States)

    Pisati, G; Cerri, S; Achille, G; Rossi, G; Lorenzi, G

    2007-01-01

    In many sports (such as rock-climbing and caving) and working activities (e.g., construction and maintenance of buildings, pruning of lung-trunked trees, abseiling in wells) people run the risk of falling from a height. To prevent the effects of any potential fall, personalprotection devices consisting of at least a body holding device (i.e. a harness of some type), a lanyard and a reliable anchor are used. Reporting on the occurrence of vascular thrombosis in subjects undergoing prolonged hanging in a harness, either for work or recreation. We investigated patients treated for vascular thrombosis in our hospital in the last 5 years to identify subjects with frequent use of a harness. We identified a 36-year-old rock-climber who developed pulmonary thrombo-embolism and infarction 5 days after he had been wearing a harness for 12 hours consecutively, and a 32 year-old worker who often used a harness to fix wire-nettings to prevent rocks falling from steep places and suffered thrombosis of the left superficial femoral artery. A feature of both cases was the considerable length of time spent hanging in the harness and the absence of alternative risk factors for thrombosis. Prolonged hanging in a harness can be dangerous in itself because it can produce vascular thrombosis. Reduction of intravascular blood flow (stasis) and compression of the femoral veins by harness groin straps were the likely pathogenetic mechanisms of the described diseases. The importance is stressed of prevention, which must be based on planned regular breaks in the hanging position, checking on the fit and comfort level of the harness before it is first used, as well as medical surveillance of the subjects who spend prolonged periods in a harness for work or recreation.

  16. Semantics-based Automated Web Testing

    OpenAIRE

    Hai-Feng Guo; Qing Ouyang; Harvey Siy

    2015-01-01

    We present TAO, a software testing tool performing automated test and oracle generation based on a semantic approach. TAO entangles grammar-based test generation with automated semantics evaluation using a denotational semantics framework. We show how TAO can be incorporated with the Selenium automation tool for automated web testing, and how TAO can be further extended to support automated delta debugging, where a failing web test script can be systematically reduced based on grammar-direct...

  17. Model-Based Testing of Probabilistic Systems

    NARCIS (Netherlands)

    Gerhold, Marcus; Stoelinga, Mariëlle Ida Antoinette; Stevens, Perdita; Wasowski, Andzej

    This paper presents a model-based testing framework for probabilistic systems. We provide algorithms to generate, execute and evaluate test cases from a probabilistic requirements model. In doing so, we connect ioco-theory for model-based testing and statistical hypothesis testing: our ioco-style

  18. Alternative scenarios: harnessing mid-level providers and evidence-based practice in primary dental care in England through operational research

    OpenAIRE

    Wanyonyi, Kristina L.; Radford, David R.; Harper, Paul R.; Gallagher, Jennifer E.

    2015-01-01

    Background: In primary care dentistry, strategies to reconfigure the traditional boundaries of various dental professional groups by task sharing and role substitution have been encouraged in order to meet changing oral health needs. Aim: The aim of this research was to investigate the potential for skill mix use in primary dental care in England based on the undergraduate training experience in a primary care team training centre for dentists and mid-level dental providers. Methods: An opera...

  19. Semantics-based Automated Web Testing

    Directory of Open Access Journals (Sweden)

    Hai-Feng Guo

    2015-08-01

    Full Text Available We present TAO, a software testing tool performing automated test and oracle generation based on a semantic approach. TAO entangles grammar-based test generation with automated semantics evaluation using a denotational semantics framework. We show how TAO can be incorporated with the Selenium automation tool for automated web testing, and how TAO can be further extended to support automated delta debugging, where a failing web test script can be systematically reduced based on grammar-directed strategies. A real-life parking website is adopted throughout the paper to demonstrate the effectivity of our semantics-based web testing approach.

  20. Quick-disconnect harness system for helmet-mounted displays

    Science.gov (United States)

    Bapu, P. T.; Aulds, M. J.; Fuchs, Steven P.; McCormick, David M.

    1992-10-01

    We have designed a pilot's harness-mounted, high voltage quick-disconnect connectors with 62 pins, to transmit voltages up to 13.5 kV and video signals with 70 MHz bandwidth, for a binocular helmet-mounted display system. It connects and disconnects with power off, and disconnects 'hot' without pilot intervention and without producing external sparks or exposing hot embers to the explosive cockpit environment. We have implemented a procedure in which the high voltage pins disconnect inside a hermetically-sealed unit before the physical separation of the connector. The 'hot' separation triggers a crowbar circuit in the high voltage power supplies for additional protection. Conductor locations and shields are designed to reduce capacitance in the circuit and avoid crosstalk among adjacent circuits. The quick- disconnect connector and wiring harness are human-engineered to ensure pilot safety and mobility. The connector backshell is equipped with two hybrid video amplifiers to improve the clarity of the video signals. Shielded wires and coaxial cables are molded as a multi-layered ribbon for maximum flexibility between the pilot's harness and helmet. Stiff cabling is provided between the quick-disconnect connector and the aircraft console to control behavior during seat ejection. The components of the system have been successfully tested for safety, performance, ergonomic considerations, and reliability.

  1. Model-based testing for software safety

    NARCIS (Netherlands)

    Gurbuz, Havva Gulay; Tekinerdogan, Bedir

    2017-01-01

    Testing safety-critical systems is crucial since a failure or malfunction may result in death or serious injuries to people, equipment, or environment. An important challenge in testing is the derivation of test cases that can identify the potential faults. Model-based testing adopts models of a

  2. Atomic Action Refinement in Model Based Testing

    NARCIS (Netherlands)

    van der Bijl, H.M.; Rensink, Arend; Tretmans, G.J.

    2007-01-01

    In model based testing (MBT) test cases are derived from a specification of the system that we want to test. In general the specification is more abstract than the implementation. This may result in 1) test cases that are not executable, because their actions are too abstract (the implementation

  3. Harnessing Disorder in Compression Based Nanofabrication

    Science.gov (United States)

    Engel, Clifford John

    The future of nanotechnologies depends on the successful development of versatile, low-cost techniques for patterning micro- and nanoarchitectures. While most approaches to nanofabrication have focused primarily on making periodic structures at ever smaller length scales with an ultimate goal of massively scaling their production, I have focused on introducing control into relatively disordered nanofabrication systems. Well-ordered patterns are increasingly unnecessary for a growing range of applications, from anti-biofouling coatings to light trapping to omniphobic surfaces. The ability to manipulate disorder, at will and over multiple length scales, starting with the nanoscale, can open new prospects for textured substrates and unconventional applications. Taking advantage of previously considered defects; I have been able to develop nanofabrication techniques with potential for massive scalability and the incorporation into a wide range of potential application. This thesis first describes the manipulation of the non-Newtonian properties of liquid Ga and Ga alloys to confine the metal and metal alloys in gratings with sub-wavelength periodicities. Through a solid to liquid phase change, I was able to access the superior plasmonic properties of liquid Ga for the generation of surface plasmon polaritons (SPP). The switching contract between solid and liquid Ga confine in the nanogratings allowed for reversible manipulation of SPP properties through heating and cooling around the relatively low melting temperature of Ga (29.8 °C). The remaining chapters focus on the development and characterization of an all polymer wrinkle material system. Wrinkles, spontaneous disordered features that are produced in response to compressive force, are an ideal for a growing number of applications where fine feature control is no longer the main motivation. However the mechanical limitations of many wrinkle systems have restricted the potential applications of wrinkled surfaces. We developed a wrinkle material system that could be both tuned in feature size from as small as 30 nm up 10 ?m while maximizing the wrinkle amplitude at all wavelengths. By charactering the material properties of both the skin and substrate, we were able to generate wrinkle patterns with fine control over periodicity, amplitude, and orientation. The final chapters of this thesis focuses on the transfer of the wrinkle structure into functional materials aimed at manipulating biological adhesion of cells, optical absorption of solar cells, and sensor sensitivity of Raman substrates. The success of these applications was directly relative to the capabilities of our wrinkle system in controlling the surface chemistry, tuning the periodicity, and maximizing the amplitude for each application.

  4. Trace-Based Code Generation for Model-Based Testing

    NARCIS (Netherlands)

    Kanstrén, T.; Piel, E.; Gross, H.G.

    2009-01-01

    Paper Submitted for review at the Eighth International Conference on Generative Programming and Component Engineering. Model-based testing can be a powerful means to generate test cases for the system under test. However, creating a useful model for model-based testing requires expertise in the

  5. Model-Based Testing: The New Revolution in Software Testing

    Directory of Open Access Journals (Sweden)

    Hitesh KUMAR SHARMA

    2014-05-01

    Full Text Available The efforts spent on testing are enormous due to the continuing quest for better software quality, and the ever growing complexity of software systems. The situation is aggravated by the fact that the complexity of testing tends to grow faster than the complexity of the systems being tested, in the worst case even exponentially. Whereas development and construction methods for software allow the building of ever larger and more complex systems, there is a real danger that testing methods cannot keep pace with construction, hence these new systems cannot be sufficiently fast and thoroughly be tested. This may seriously hamper the development of future generations of software systems. One of the new technologies to meet the challenges imposed on software testing is model-based testing. Models can be utilized in many ways throughout the product life-cycle, including: improved quality of specifications, code generation, reliability analysis, and test generation. This paper will focus on the testing benefits from MBT methods and review some of the historical challenges that prevented model based testing and we also try to present the solutions that can overcome these challenges.

  6. Strain measurement based battery testing

    Science.gov (United States)

    Xu, Jeff Qiang; Steiber, Joe; Wall, Craig M.; Smith, Robert; Ng, Cheuk

    2017-05-23

    A method and system for strain-based estimation of the state of health of a battery, from an initial state to an aged state, is provided. A strain gauge is applied to the battery. A first strain measurement is performed on the battery, using the strain gauge, at a selected charge capacity of the battery and at the initial state of the battery. A second strain measurement is performed on the battery, using the strain gauge, at the selected charge capacity of the battery and at the aged state of the battery. The capacity degradation of the battery is estimated as the difference between the first and second strain measurements divided by the first strain measurement.

  7. Medicinalindustrien har brug for diagnoser som ADHD

    DEFF Research Database (Denmark)

    Fugl, Marie

    2008-01-01

    Det er ikke første gang, at medicinalindustriens evne til at finde nye markeder har medført nye eller bredere diagnoser. I det forrige årti så vi et parallelt forløb mellem et boom i antallet af depressionsdiagnoser og forbruget af lykkepiller. Interview med sociolog Thomas Brante. Udgivelsesdato...

  8. Økonomer har et forklaringsproblem

    DEFF Research Database (Denmark)

    Rangvid, Jesper

    2016-01-01

    Markederne toppede i april/maj 2015 og har haft det svært siden. Meget tyder 2016 er startet med voldsomme fald på de globale aktiemarkeder. Det er muligvis med rette for nogle banker, men overordnet er sektoren mere robust, ikke mindst grundet bedre regulering, end før finanskrisen i 2008...

  9. SRB Altitude Switch Assembly Wire Harness Failure

    Science.gov (United States)

    Blanche, Jim

    2002-01-01

    This paper presents an assessment of two wire harness failures that had occurred in Solid Rocket Booster Altitude Switch Assemblies S/N 200001 and S/N 20002. A list of modifications to EDU #4 and modification of qualification units 2000001 and 2000002 are also presented.

  10. Kyllinger har effektivt immunforsvar mod herpes

    DEFF Research Database (Denmark)

    Buchmann, Kurt

    2008-01-01

    Forskere ved Københavns Universitet, Fakultet for Biovidenskab har studeret kyllingens MHC molekyler og kan derigennem forklare hvorfor en særlig stamme indenfor denne art er modstandsdygtige mod en særlig herpesvirus. Udgivelsesdato: 18. januar 2008...

  11. Harnessing science to improve safety.

    Science.gov (United States)

    Baillie, Jonathan

    2011-01-01

    Examining the effectiveness of various wet surface cleaning methods in combating harmful microorganisms in a hospital ward, understanding different healthcare cleaning regimes' impact on reducing slips and trips, evaluating the protection offered by surgical masks against influenza bioaerosols, and independently testing tower crane safety following a number of fatal incidents, are among the broad spectrum of recent projects undertaken by the Buxton-headquartered Health and Safety Laboratory (HSL). As HEJ editor Jonathan Baillie discovered from the organisation's healthcare and patient safety lead, Darren Whitehouse, with around 350 scientists skilled in everything from microbiology to occupational psychology, the range of scientific guidance, expertise, advice, testing, training, and investigation, that the HSL can offer to the healthcare sector is perhaps unrivalled throughout Europe.

  12. Harness Traction Technique (HARNESS): Novel Method for Controlling the Transection Plane During Laparoscopic Hepatectomy.

    Science.gov (United States)

    Itano, Osamu; Oshima, Go; Kitago, Minoru; Suzuki, Keiichi; Hayatsu, Shigeo; Shinoda, Masahiro; Abe, Yuta; Hibi, Taizo; Yagi, Hiroshi; Ikoma, Naruhiko; Aiko, Satoshi; Kitagawa, Yuko

    2015-08-01

    We present our experience using a novel method for controlling the transection plane, which we termed as the Harness Traction Technique (HARNESS) and evaluate its usefulness. From May 2009 to March 2012, laparoscopic hepatectomies using HARNESS were performed on 35 patients. After the superficial hepatic parenchyma on the line was transected at 1 to 2 cm depth, 5 mm tape was placed along the groove of the line and tied to prevent it from slipping off. Tape was tied and pulled using a forceps toward the best direction for minimizing the bleeding, moving the transection point to the appropriate position and creating good tension for parenchymal transection at the transection point. There were no conversions to laparotomy or intraoperative complications. HARNESS is useful for controlling the dissection line during laparoscopic hepatectomy, leading to precise and safe laparoscopic liver parenchymal dissection.

  13. Arbejdsulykker! Alle har en historie

    DEFF Research Database (Denmark)

    Richter, Anne; Pedersen, Elsebet Frydendal

    in a trade school and in three carpentry companies in relation to five construction sites. The project draws on organizational culture theories of symbolic interactionism and on practice based learning i communities of practice. The methodological approach is primarily ethnographic. Four different cultures...

  14. Solar Radiation: Harnessing the Power

    Science.gov (United States)

    Rowland, Teri; Chambers, Lin; Holzer, Missy; Moore, Susan

    2009-01-01

    My NASA Data (Chambers et al. 2008) is a teaching tool available on NASA's website that offers microsets of real data in an easily accessible, user-friendly format. In this article, the authors describe a lesson plan based on an activity from My NASA Data, in which students explore parts of the United States where they would want to live if they…

  15. Harness the Energy of Collaboration

    Science.gov (United States)

    Lieberman, Ann; Miller, Lynne

    2016-01-01

    As they write about the Learning Communities standard in "Reach the Highest Standard in Professional Learning: Learning Communities," authors Ann Lieberman and Lynne Miller consider why communities have gained widespread attention and support and summarize the established research base about them. They also describe three contexts in…

  16. HARNESSING INTELLECTUAL PROPERTY FOR DEVELOPMENT ...

    African Journals Online (AJOL)

    10332324

    on Limitations and Exceptions for Visually Impaired Persons/Persons with Print. Disabilities was adopted at a ... access to knowledge for learners and the visually impaired.5 Another topical IP issue is the protection of .... used to evaluate the appropriateness of IP protection in South Africa. This framework is based on three ...

  17. The Ideal Base For Patch Testing

    Directory of Open Access Journals (Sweden)

    Ashok Kumar Bajaj

    1984-01-01

    Full Text Available A study was conducted to find out a suitable vehicle for patch testing in India. Various bases: tested were petrolatum, propylene glycol, polyethylene glycol 400, lanolin, olive, oil and plastobase. The observations suggest that polythylene glycol 400 is the most suitable vehicle for patch testing.

  18. Dry Electrode Harness System For Wireless 12-LEAD ECG Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The dry-electrode harness is composed of a variety of components.  The harness interfaces with the human via a commercial-off-the-shelf (COTS) FDA cleared dry...

  19. Physical Test Prototypes Based on Microcontroller

    Science.gov (United States)

    Paramitha, S. T.

    2017-03-01

    The purpose of this study was to produce a prototype of a physical test-based microcontroller. The research method uses the research and development of the Borg and gall. The procedure starts from the study; research and information collecting, planning, develop preliminary form of product, preliminary field testing, main product revision, playing field testing, operational product revision, field operational testing, final product revision, dissemination and implementation. Validation of the product, obtained through expert evaluation; test products of small scale and large scale; effectiveness test; evaluation of respondents. The results showed that the eligibility assessment of prototype products based physical tests microcontroller. Based on the ratings of seven experts showed that 87% included in the category of “very good” and 13% included in the category of “good”. While the effectiveness of the test results showed that 1). The results of the experimental group to test sit-ups increase by 40% and the control group by 15%. 2). The results of the experimental group to test push-ups increased by 30% and the control group by 10%. 3). The results of the experimental group to test the Back-ups increased by 25% and the control group by 10%. With a significant value of 0.002 less than 0.05, product means a physical test prototype microcontroller based, proven effective in improving the results of physical tests. Conclusions and recommendations; Product physical microcontroller-based assays, can be used to measure the physical tests of pushups, sit ups, and back-ups.

  20. Harnessing the Bethe free energy.

    Science.gov (United States)

    Bapst, Victor; Coja-Oghlan, Amin

    2016-12-01

    A wide class of problems in combinatorics, computer science and physics can be described along the following lines. There are a large number of variables ranging over a finite domain that interact through constraints that each bind a few variables and either encourage or discourage certain value combinations. Examples include the k-SAT problem or the Ising model. Such models naturally induce a Gibbs measure on the set of assignments, which is characterised by its partition function. The present paper deals with the partition function of problems where the interactions between variables and constraints are induced by a sparse random (hyper)graph. According to physics predictions, a generic recipe called the "replica symmetric cavity method" yields the correct value of the partition function if the underlying model enjoys certain properties [Krzkala et al., PNAS (2007) 10318-10323]. Guided by this conjecture, we prove general sufficient conditions for the success of the cavity method. The proofs are based on a "regularity lemma" for probability measures on sets of the form Ωn for a finite Ω and a large n that may be of independent interest. © 2016 Wiley Periodicals, Inc. Random Struct. Alg., 49, 694-741, 2016.

  1. Simulation-based Testing of Control Software

    Energy Technology Data Exchange (ETDEWEB)

    Ozmen, Ozgur [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Nutaro, James J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Sanyal, Jibonananda [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Olama, Mohammed M. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2017-02-10

    It is impossible to adequately test complex software by examining its operation in a physical prototype of the system monitored. Adequate test coverage can require millions of test cases, and the cost of equipment prototypes combined with the real-time constraints of testing with them makes it infeasible to sample more than a small number of these tests. Model based testing seeks to avoid this problem by allowing for large numbers of relatively inexpensive virtual prototypes that operate in simulation time at a speed limited only by the available computing resources. In this report, we describe how a computer system emulator can be used as part of a model based testing environment; specifically, we show that a complete software stack including operating system and application software - can be deployed within a simulated environment, and that these simulations can proceed as fast as possible. To illustrate this approach to model based testing, we describe how it is being used to test several building control systems that act to coordinate air conditioning loads for the purpose of reducing peak demand. These tests involve the use of ADEVS (A Discrete Event System Simulator) and QEMU (Quick Emulator) to host the operational software within the simulation, and a building model developed with the MODELICA programming language using Buildings Library and packaged as an FMU (Functional Mock-up Unit) that serves as the virtual test environment.

  2. Model-based testing for embedded systems

    CERN Document Server

    Zander, Justyna; Mosterman, Pieter J

    2011-01-01

    What the experts have to say about Model-Based Testing for Embedded Systems: "This book is exactly what is needed at the exact right time in this fast-growing area. From its beginnings over 10 years ago of deriving tests from UML statecharts, model-based testing has matured into a topic with both breadth and depth. Testing embedded systems is a natural application of MBT, and this book hits the nail exactly on the head. Numerous topics are presented clearly, thoroughly, and concisely in this cutting-edge book. The authors are world-class leading experts in this area and teach us well-used

  3. Harnessing the wisdom of the inner crowd.

    Science.gov (United States)

    Herzog, Stefan M; Hertwig, Ralph

    2014-10-01

    Ever since Galton's classic demonstration of the wisdom of crowds in estimating the weight of a slaughtered ox, scholars of the mind and the public alike have been fascinated by the counterintuitive accuracy achieved by simply averaging a number of people's estimates. Surprisingly, individuals can, to some extent, harness the wisdom of crowds within the confines of their own mind by averaging self-generated, nonredundant estimates. Copyright © 2014 Elsevier Ltd. All rights reserved.

  4. Traceability in Model-Based Testing

    Directory of Open Access Journals (Sweden)

    Mathew George

    2012-11-01

    Full Text Available The growing complexities of software and the demand for shorter time to market are two important challenges that face today’s IT industry. These challenges demand the increase of both productivity and quality of software. Model-based testing is a promising technique for meeting these challenges. Traceability modeling is a key issue and challenge in model-based testing. Relationships between the different models will help to navigate from one model to another, and trace back to the respective requirements and the design model when the test fails. In this paper, we present an approach for bridging the gaps between the different models in model-based testing. We propose relation definition markup language (RDML for defining the relationships between models.

  5. How can developing countries harness biotechnology to improve health?

    Science.gov (United States)

    Daar, Abdallah S; Berndtson, Kathryn; Persad, Deepa L; Singer, Peter A

    2007-12-03

    The benefits of genomics and biotechnology are concentrated primarily in the industrialized world, while their potential to combat neglected diseases in the developing world has been largely untapped. Without building developing world biotechnology capacity to address local health needs, this disparity will only intensify. To assess the potential of genomics to address health needs in the developing world, the McLaughlin-Rotman Centre for Global Health, along with local partners, organized five courses on Genomics and Public Health Policy in the developing world. The overall objective of the courses was to collectively explore how to best harness genomics to improve health in each region. This article presents and analyzes the recommendations from all five courses. In this paper we analyze recommendations from 232 developing world experts from 58 countries who sought to answer how best to harness biotechnology to improve health in their regions. We divide their recommendations into four categories: science; finance; ethics, society and culture; and politics. The Courses' recommendations can be summarized across the four categories listed above: SCIENCE: - Collaborate through national, regional, and international networks- Survey and build capacity based on proven models through education, training, and needs assessments FINANCE: - Develop regulatory and intellectual property frameworks for commercialization of biotechnology- Enhance funding and affordability of biotechnology- Improve the academic-industry interface and the role of small and medium enterprise ETHICS, SOCIETY, CULTURE: - Develop public engagement strategies to inform and educate the public about developments in genomics and biotechnology- Develop capacity to address ethical, social and cultural issues- Improve accessibility and equity POLITICS: - Strengthen understanding, leadership and support at the political level for biotechnology- Develop policies outlining national biotechnology strategy

  6. How can developing countries harness biotechnology to improve health?

    Directory of Open Access Journals (Sweden)

    Persad Deepa L

    2007-12-01

    Full Text Available Abstract Background The benefits of genomics and biotechnology are concentrated primarily in the industrialized world, while their potential to combat neglected diseases in the developing world has been largely untapped. Without building developing world biotechnology capacity to address local health needs, this disparity will only intensify. To assess the potential of genomics to address health needs in the developing world, the McLaughlin-Rotman Centre for Global Health, along with local partners, organized five courses on Genomics and Public Health Policy in the developing world. The overall objective of the courses was to collectively explore how to best harness genomics to improve health in each region. This article presents and analyzes the recommendations from all five courses. Discussion In this paper we analyze recommendations from 232 developing world experts from 58 countries who sought to answer how best to harness biotechnology to improve health in their regions. We divide their recommendations into four categories: science; finance; ethics, society and culture; and politics. Summary The Courses' recommendations can be summarized across the four categories listed above: Science - Collaborate through national, regional, and international networks - Survey and build capacity based on proven models through education, training, and needs assessments Finance - Develop regulatory and intellectual property frameworks for commercialization of biotechnology - Enhance funding and affordability of biotechnology - Improve the academic-industry interface and the role of small and medium enterprise Ethics, Society, Culture - Develop public engagement strategies to inform and educate the public about developments in genomics and biotechnology - Develop capacity to address ethical, social and cultural issues - Improve accessibility and equity Politics - Strengthen understanding, leadership and support at the political level for biotechnology

  7. Development of an alternative five-point restraint harness to accommodate children with special healthcare needs in child safety seats.

    Science.gov (United States)

    Brinkey, Lori; Manary, Miriam; Santioni, Daniel

    2011-01-01

    Commercial automotive child restraint systems (CRSs) do not accommodate all children with special healthcare needs. This study developed an alternative harness for a commercial CRS to meet the needs of children for whom a five-point harness cannot be positioned over medically involved areas and/or children whose conditions require the harness belts to be threaded through medical devices. After initial design work and a series of frontal sled-impact tests, one of two prototype designs was chosen for fit testing on children with and without healthcare conditions. After a minor modification, additional sled-impact testing was conducted to determine compliance of the system to federal standards. The CRS with alternate harness provides good fit to children with a variety of healthcare needs and complies with all performance criteria of FMVSS 213, with the exception of peak forward head excursion using the Hybrid III 6-year-old crash-test dummy. It is expected that all performance criteria will be met using the newly-issued federal allowance to conduct CRS frontal-impact tests using an earlier version of the dummy. The new harness shows promise as a low-cost solution for achieving a safer level of transportation for children who may otherwise travel unrestrained or with a severely misused CRS harness.

  8. Testlet-based Multidimensional Adaptive Testing

    Directory of Open Access Journals (Sweden)

    Andreas Frey

    2016-11-01

    Full Text Available Multidimensional adaptive testing (MAT is a highly efficient method for the simultaneous measurement of several latent traits. Currently, no psychometrically sound approach is available for the use of MAT in testlet-based tests. Testlets are sets of items sharing a common stimulus such as a graph or a text. They are frequently used in large operational testing programs like TOEFL, PISA, PIRLS, or NAEP. To make MAT accessible for such testing programs, we present a novel combination of MAT with a multidimensional generalization of the random effects testlet model (MAT-MTIRT. MAT-MTIRT compared to non-adaptive testing is examined for several combinations of testlet effect variances (0.0, 0.5, 1.0, 1.5 and testlet sizes (3 items, 6 items, 9 items with a simulation study considering three ability dimensions with simple loading structure. MAT-MTIRT outperformed non-adaptive testing regarding the measurement precision of the ability estimates. Further, the measurement precision decreased when testlet effect variances and testlet sizes increased. The suggested combination of the MTIRT model therefore provides a solution to the substantial problems of testlet-based tests while keeping the length of the test within an acceptable range.

  9. Testlet-Based Multidimensional Adaptive Testing.

    Science.gov (United States)

    Frey, Andreas; Seitz, Nicki-Nils; Brandt, Steffen

    2016-01-01

    Multidimensional adaptive testing (MAT) is a highly efficient method for the simultaneous measurement of several latent traits. Currently, no psychometrically sound approach is available for the use of MAT in testlet-based tests. Testlets are sets of items sharing a common stimulus such as a graph or a text. They are frequently used in large operational testing programs like TOEFL, PISA, PIRLS, or NAEP. To make MAT accessible for such testing programs, we present a novel combination of MAT with a multidimensional generalization of the random effects testlet model (MAT-MTIRT). MAT-MTIRT compared to non-adaptive testing is examined for several combinations of testlet effect variances (0.0, 0.5, 1.0, and 1.5) and testlet sizes (3, 6, and 9 items) with a simulation study considering three ability dimensions with simple loading structure. MAT-MTIRT outperformed non-adaptive testing regarding the measurement precision of the ability estimates. Further, the measurement precision decreased when testlet effect variances and testlet sizes increased. The suggested combination of the MTIRT model therefore provides a solution to the substantial problems of testlet-based tests while keeping the length of the test within an acceptable range.

  10. The serial harness interacting with a wall

    OpenAIRE

    Ferrari, P. A.; Fontes, L. R. G.; Niederhauser, B.; Vachkovskaia, M.

    2002-01-01

    The serial harnesses introduced by Hammersley describe the motion of a hypersurface of dimension d embedded in a space of dimension $d+1$. The height assigned to each site i of Z^d is updated by taking a weighted average of the heights of some of the neighbors of i plus a ``noise'' (a centered random variable). The surface interacts by exclusion with a ``wall'' located at level zero: the updated heights are not allowed to go below zero. We show that for any distribution of the noise variables...

  11. Harnessing the Properties of Natural Products.

    Science.gov (United States)

    Boufridi, Asmaa; Quinn, Ronald J

    2018-01-06

    Natural products (NPs) have been used as traditional medicines since antiquity. With more than 10 60 estimated compounds with molecular weights less than 500 Da representing chemical space, NPs occupy a very small percentage; however, they are significantly overrepresented in biologically relevant chemical space. The classical approach concentrates on identifying one or more NPs with biological activity from a source organism. There is much more to be learned from NPs than we can discover this narrow view. In this review, we discuss ways to harness the global properties of NPs.

  12. Hvordan har jeg det i dag?

    DEFF Research Database (Denmark)

    Kappelgaard, Lisbeth

    stress. En central problemstilling er her at stress er ’vanskeligt at tage i opløbet’. Med afsæt i denne problemstilling udvikles metoden Ecological Momentary storytelling (EMS) - en metode, der ved hjælp af ’ecological momentary assessments’ og refleksive dialoger anvendes til at ’spore’ stressorer i...... casestudie, hvor kliniske møder mellem patient og sundhedsprofessionelle gøres til genstand for interaktionsanalyse. Herigennem tilvejebringes indblik i, hvilke udfordringer der kan være forbundet med selvmonitoreringspraksis, når man har Sundhedsstyrelsens ønsker og forventninger som udgangspunkt....

  13. Suspension tolerance in a full-body safety harness, and a prototype harness accessory.

    Science.gov (United States)

    Turner, Nina L; Wassell, James T; Whisler, Richard; Zwiener, Joyce

    2008-04-01

    Workers wearing full-body safety harnesses are at risk for suspension trauma if they are not rescued in 5 to 30 min after a successfully arrested fall. Suspension trauma, which may be fatal, occurs when a person's legs are immobile in a vertical posture, leading to the pooling of blood in the legs, pelvis, and abdomen, and the reduction of return blood flow to the heart and brain. To measure suspension tolerance time, 22 men and 18 women with construction experience were suspended from the chest D-ring (CHEST) and back D-ring (BACK) of full-body, fall-arrest harnesses. Fifteen men and 13 women from the original group of subjects were then suspended using a newly developed National Institute for Occupational Safety and Health harness accessory (ACCESS), which supports the upper legs. Midthigh circumference changes were 1.4 and 1.9 cm, changes in minute ventilation were 1.2 and 1.5 L/min, changes in heart rate (HR) were 15.1 and 21.6 bpm, and changes in mean arterial pressure were 5.1 and -2.6 mmHg (p harness accessory to delay or prevent suspension trauma.

  14. Trunk Muscle Activation and Estimating Spinal Compressive Force in Rope and Harness Vertical Dance.

    Science.gov (United States)

    Wilson, Margaret; Dai, Boyi; Zhu, Qin; Humphrey, Neil

    2015-12-01

    Rope and harness vertical dance takes place off the floor with the dancer suspended from his or her center of mass in a harness attached to a rope from a point overhead. Vertical dance represents a novel environment for training and performing in which expected stresses on the dancer's body are different from those that take place during dance on the floor. Two male and eleven female dancers with training in vertical dance performed six typical vertical dance movements with electromyography (EMG) electrodes placed bilaterally on rectus abdominus, external oblique, erector spinae, and latissimus dorsi. EMG data were expressed as a percentage of maximum voluntary isometric contraction (MVIC). A simplified musculoskeletal model based on muscle activation for these four muscle groups was used to estimate the compressive force on the spine. The greatest muscle activation for erector spinae and latissimus dorsi and the greatest trunk compressive forces were seen in vertical axis positions where the dancer was moving the trunk into a hyper-extended position. The greatest muscle activation for rectus abdominus and external oblique and the second highest compressive force were seen in a supine position with the arms and legs extended away from the center of mass (COM). The least muscle activation occurred in positions where the limbs were hanging below the torso. These movements also showed relatively low muscle activation compression forces. Post-test survey results revealed that dancers felt comfortable in these positions; however, observation of some positions indicated insufficient muscular control. Computing the relative contribution of muscles, expressed as muscle activation and estimated spinal compression, provided a measure of how much the muscle groups were working to support the spine and the rest of the dancer's body in the different movements tested. Additionally, identifying typical muscle recruitment patterns in each movement will help identify key exercises

  15. Forum: Is Test-Based Accountability Dead?

    Science.gov (United States)

    Polikoff, Morgan S.; Greene, Jay P.; Huffman, Kevin

    2017-01-01

    Since the 2001 passage of the No Child Left Behind Act (NCLB), test-based accountability has been an organizing principle--perhaps "the" organizing principle--of efforts to improve American schools. But lately, accountability has been under fire from many critics, including Common Core opponents and those calling for more multifaceted…

  16. Diagnostic tests based on human basophils

    DEFF Research Database (Denmark)

    Kleine-Tebbe, Jörg; Erdmann, Stephan; Knol, Edward F

    2006-01-01

    for diagnostic purposes, each allergen should be pre-evaluated separately in order to determine a suitable stimulation range. Additionally, anti-IgE or anti-FcepsilonRIalpha antibodies should serve as positive controls, bearing in mind that 10-20% of basophil donors are not responsive to IgE-mediated stimulation....... Diagnostic studies using CD63 or CD203c in hymenoptera, food and drug allergy are critically discussed. Basophil-based tests are indicated for allergy testing in selected cases but should only be performed by experienced laboratories....

  17. Registration of two confection sunflower germplasm Lines, HA-R10 and HA-R11, Resistant to sunflower rust

    Science.gov (United States)

    Two confection sunflower (Helianthus annuus L.) germplasm lines, HA-R10 (Reg. No.xxx, PI670043) and HA-R11 (Reg. No.xxx, PI670044) were developed by the USDA-ARS Sunflower and Plant Biology Research Unit in collaboration with the North Dakota Agricultural Experiment Station and released December, 20...

  18. Registration of two double rust resistant germplasms, HA-R12 and HA-R13 for confection sunflower

    Science.gov (United States)

    The confection sunflower (Helianthus annuus L.) germplasms HA-R12 (Reg. No. ______, PI 673104) and HA-R13 (Reg. No. ______, PI 673105) were developed by the USDA-ARS, Sunflower and Plant Biology Research Unit in collaboration with the North Dakota Agricultural Experiment Station, and released in Jul...

  19. Antirandom Testing: A Distance-Based Approach

    Directory of Open Access Journals (Sweden)

    Shen Hui Wu

    2008-01-01

    Full Text Available Random testing requires each test to be selected randomly regardless of the tests previously applied. This paper introduces the concept of antirandom testing where each test applied is chosen such that its total distance from all previous tests is maximum. This spans the test vector space to the maximum extent possible for a given number of vectors. An algorithm for generating antirandom tests is presented. Compared with traditional pseudorandom testing, antirandom testing is found to be very effective when a high-fault coverage needs to be achieved with a limited number of test vectors. The superiority of the new approach is even more significant for testing bridging faults.

  20. Harnessing cognitive neuroscience to develop new treatments for improving cognition in schizophrenia: CNTRICS selected cognitive paradigms for animal models.

    Science.gov (United States)

    Moore, Holly; Geyer, Mark A; Carter, Cameron S; Barch, Deanna M

    2013-11-01

    Over the past two decades, the awareness of the disabling and treatment-refractory effects of impaired cognition in schizophrenia has increased dramatically. In response to this still unmet need in the treatment of schizophrenia, the Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia (CNTRICS) initiative was developed. The goal of CNTRICS is to harness cognitive neuroscience to develop a brain-based set of tools for measuring cognition in schizophrenia and to test new treatments. CNTRICS meetings focused on development of tasks with cognitive construct validity for use in both human and animal model studies. This special issue presents papers discussing the cognitive testing paradigms selected by CNTRICS for animal model systems. These paradigms are designed to measure cognitive constructs within the domains of perception, attention, executive function, working memory, object/relational long-term memory, and social/affective processes. Copyright © 2013. Published by Elsevier Ltd.

  1. Harnessing the native type I-B CRISPR-Cas for genome editing in a polyploid archaeon.

    Science.gov (United States)

    Cheng, Feiyue; Gong, Luyao; Zhao, Dahe; Yang, Haibo; Zhou, Jian; Li, Ming; Xiang, Hua

    2017-11-20

    Research on CRISPR-Cas (clustered regularly interspaced short palindromic repeats-CRISPR associated protein) systems has led to the revolutionary CRISPR/Cas9 genome editing technique. However, for most archaea and half of bacteria, exploitation of their native CRISPR-Cas machineries may be more straightforward and convenient. In this study, we harnessed the native type I-B CRISPR-Cas system for precise genome editing in the polyploid haloarchaeon Haloarcula hispanica. After testing different designs, the editing tool was optimized to be a single plasmid that carries both the self-targeting mini-CRISPR and a 600-800 bp donor. Significantly, chromosomal modifications, such as gene deletion, gene tagging or single nucleotide substitution, were precisely introduced into the vast majority of the transformants. Moreover, we showed that simultaneous editing of two genomic loci could also be readily achieved by one step. In summary, our data demonstrate that the haloarchaeal CRISPR-Cas system can be harnessed for genome editing in this polyploid archaeon, and highlight the convenience and efficiency of the native CRISPR-based genome editing strategy. Copyright © 2017 Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, and Genetics Society of China. Published by Elsevier Ltd. All rights reserved.

  2. Harnessing coherence of area decomposition and semantic shared spaces for task allocation in a robotic fleet

    Directory of Open Access Journals (Sweden)

    Domagoj Drenjanac

    2014-08-01

    Full Text Available Task allocation is a fundamental problem in multi-robot systems where heterogeneous robots cooperate to perform a complex mission. A general requirement in a task allocation algorithm is to find an optimal set of robots to execute a certain task. This paper presents the work that harnesses an area decomposition algorithm, and a space-based middleware to facilitate task allocation process in unstructured and dynamic environments. To reduce spatial interference between robots, area decomposition algorithm divides a working area into cells which are then dynamically assigned to robots. In addition, coordination and collaboration among distributed robots are realized through a space-based middleware. For this purpose, the space-based middleware is extended with a semantic model of robot capabilities to improve task selection in terms of flexibility, scalability, and reduced communication overhead during task allocation. In this way a framework which exploits the synergy of area decomposition and semantically enriched space-based approach is created. We conducted performance tests in a specific precision agriculture use case focusing on the utilization of a robotic fleet for weed control introduced in the European Project RHEA – Robot Fleets for Highly Effective Agriculture and Forestry Management.

  3. Harnessing nanomedicine for therapeutic intervention in glioblastoma.

    Science.gov (United States)

    Gutkin, Anna; Cohen, Zvi R; Peer, Dan

    2016-11-01

    Glioblastoma is a type of brain cancer arises from glial cells. Glioblastoma multiforme (GBM), a subtype of glioblastoma, is the most common and most aggressive primary brain tumor. Currently, GBM therapy includes surgery and post-operative high-doses of radiation and chemotherapy. This therapeutic strategy has a limited contribution in extending the survival rate of GBM patients. Areas covered: Herein, we focus on harnessing nanoscale drug delivery strategies to treat brain malignancies. Specifically, we briefly discuss the challenges facing GBM therapy such as restricted passage across the blood-brain barrier (BBB) and low enhanced permeability and retention effect. Next, we describe different pathways to address these challenges. Finally, we discuss the field of nanomedicine, which emerged as a promising platform for drug delivery to brain malignancies. Expert opinion: Countless strategies have been applied in preclinical and clinical settings to treat GBM. Among them is the use of different types of nanoparticles (NPs) and viruses with different approaches to cross or bypass the BBB. We suggest here a paradigm shift in thinking about crossing the BBB and tumor penetration as fundamental issues that need to be address in order to improve the therapeutic outcome in GBM.

  4. Hvor mange betydninger har et ord

    DEFF Research Database (Denmark)

    Bergenholtz, Henning; Toftgaard Madsen, August

    2017-01-01

    artikler, som August har skrevet til Den Danske Betydningsordbog: trøske, tonisk, tonnage, topskud, topstykke, toradet, tornerosesøvn, touch, trykkoger, træhammer, trøffel. Ud fra analysen af disse eksempler udleder vi følgende metodiske tese: I forbindelse med receptionsproblem laves polysemi, når et...... bestemt ord bruges i forskellige sammenhænge og refererer til forskellige ting eller handlinger. Hvis leksikografen er i tvivl om polysemi eller ej, vælges polysemi. Vi udleder to teoretiske teser: 1. Lemmaselektion og polysemiselektion er to sider af samme sag 2 Det gælder især, hvis man afskaffer...... homonymi og polysemi, sådan foreslår Bergenholtz/Agerbo (2014), så er polysemiselektion og lemmaselektion det samme. Herfor kan bruges den fælles betegnelse: artikelselektion med to metodiske skridt (1. udtryksselektion (lemmaselektion), 2. indholdsselektion, hvis et udtryk kan forbindes med mere end et...

  5. Harnessing adolescent values to motivate healthier eating.

    Science.gov (United States)

    Bryan, Christopher J; Yeager, David S; Hinojosa, Cintia P; Chabot, Aimee; Bergen, Holly; Kawamura, Mari; Steubing, Fred

    2016-09-27

    What can be done to reduce unhealthy eating among adolescents? It was hypothesized that aligning healthy eating with important and widely shared adolescent values would produce the needed motivation. A double-blind, randomized, placebo-controlled experiment with eighth graders (total n = 536) evaluated the impact of a treatment that framed healthy eating as consistent with the adolescent values of autonomy from adult control and the pursuit of social justice. Healthy eating was suggested as a way to take a stand against manipulative and unfair practices of the food industry, such as engineering junk food to make it addictive and marketing it to young children. Compared with traditional health education materials or to a non-food-related control, this treatment led eighth graders to see healthy eating as more autonomy-assertive and social justice-oriented behavior and to forgo sugary snacks and drinks in favor of healthier options a day later in an unrelated context. Public health interventions for adolescents may be more effective when they harness the motivational power of that group's existing strongly held values.

  6. Trait-based tests of coexistence mechanisms.

    Science.gov (United States)

    Adler, Peter B; Fajardo, Alex; Kleinhesselink, Andrew R; Kraft, Nathan J B

    2013-10-01

    Recent functional trait studies have shown that trait differences may favour certain species (environmental filtering) while simultaneously preventing competitive exclusion (niche partitioning). However, phenomenological trait-dispersion analyses do not identify the mechanisms that generate niche partitioning, preventing trait-based prediction of future changes in biodiversity. We argue that such predictions require linking functional traits with recognised coexistence mechanisms involving spatial or temporal environmental heterogeneity, resource partitioning and natural enemies. We first demonstrate the limitations of phenomenological approaches using simulations, and then (1) propose trait-based tests of coexistence, (2) generate hypotheses about which plant functional traits are likely to interact with particular mechanisms and (3) review the literature for evidence for these hypotheses. Theory and data suggest that all four classes of coexistence mechanisms could act on functional trait variation, but some mechanisms will be stronger and more widespread than others. The highest priority for future research is studies of interactions between environmental heterogeneity and trait variation that measure environmental variables at within-community scales and quantify species' responses to the environment in the absence of competition. Evidence that similar trait-based coexistence mechanisms operate in many ecosystems would simplify biodiversity forecasting and represent a rare victory for generality over contingency in community ecology. © 2013 John Wiley & Sons Ltd/CNRS.

  7. SSME Electrical Harness and Cable Development and Evolution

    Science.gov (United States)

    Abrams, Russ; Heflin, Johnny; Burns, Bob; Camper, Scott J.; Hill, Arthur J.

    2010-01-01

    The Space Shuttle Main Engine (SSME) electrical harness and cable system consists of the various interconnecting devices necessary for operation of complex rocket engine functions. Thirty seven harnesses incorporate unique connectors, backshell adapters, conductors, insulation, shielding, and physical barriers for a long maintenance-free life while providing the means to satisfy performance requirements and to mitigate adverse environmental influences. The objective of this paper is to provide a description of the SSME electrical harness and cable designs as well as the development history and lessons learned.

  8. Harnessing Earth Observations for Disaster Application Science

    Science.gov (United States)

    Green, D. S.

    2015-12-01

    Earth observations have made substantive contributions to the understanding of natural hazards, answering key science questions on the mechanisms, processes and dynamics of changes in the land, air and water. This has been achieved through the ability to advance models and interpret the results through maps and assessments. Disaster application science is focused on the two-way flow of data and information between hazard understanding and the knowledge required for disaster response, relief and recovery. This presentation will examine the integration of results from mature science and technology development in areas including optical imagery, synthetic-aperture radar and geodetic sensors, which together provide new levels of situational awareness. Specific examples will be highlighted from the recent Nepal "Gorkha" earthquake. Optical imagery from a host of satellite missions was used to create a comprehensive mosaic across the region, which when analyzed by a global network of volunteer scientists yielded insight into the extent of induced hazards and impacts. In some cases unique day/night band images provided guidance on areas where energy-dependent infrastructure of livelihoods were disrupted. Earthquake modeling and historical trend analysis revealed areas of potential vulnerability and combined with aftershock analysis to guide areas for urgent analysis and action. The combination of SAR and GPS data, innovative integration and processing approaches and nontraditional data integration approaches resulted in damage proxy maps or where combination with airborne photography, field sightings and crowd sourced reports to assess susceptibility to induced hazards (floods and landslides). Opportunities and challenges to build the science and community relationships, harness the earth observations from multiple agencies and institutions and co-develop timely applications to users will be areas for ongoing collaboration and study.Earth observations have made

  9. Har læreplanen (stadig) minimal betydning?

    DEFF Research Database (Denmark)

    Poulsen, Jens Aage

    2016-01-01

    Undervisningsministeriets læreplaner for skolens fag er centrale styredokumenter, der fastlægger formål og rammesætter indhold og form for undervisningen. Men hvilken betydning har de i praksis?...

  10. Army Social Media: Harnessing the Power of Networked Communications

    Science.gov (United States)

    2011-09-01

    9/1/2011 Army Social Media : harnessing the power of networked communications Report Documentation Page Form ApprovedOMB No. 0704-0188 Public...4. TITLE AND SUBTITLE Army Social Media : harnessing the power of networked communications 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM...the Chief of Public Affairs,Online and Social Media Division,1500 Pentagon,Washington,DC,20301 8. PERFORMING ORGANIZATION REPORT NUMBER 9

  11. Planter har også som dyr et immunforsvar

    DEFF Research Database (Denmark)

    Buchmann, Kurt

    2007-01-01

    Planter har et system til at genkende bl.a. skadedyr og deres specifikke stoffer, hvorefter de kan aktivere en række mekanismer til at eliminere disse. Udgivelsesdato: 27. april......Planter har et system til at genkende bl.a. skadedyr og deres specifikke stoffer, hvorefter de kan aktivere en række mekanismer til at eliminere disse. Udgivelsesdato: 27. april...

  12. Pakistan: Har atomvåben stabiliseret konflikten med Indien?

    DEFF Research Database (Denmark)

    Nielsen, Thomas Galasz

    2016-01-01

    Både Pakistan og Indien har et atomvåbenprogram, men kan atomvåben stabilisere konflikten mellem de to lande? Ikke rigtigt, men våbnene har tiltrukket USA’s opmærksomhed, og det er måske den bedste mulighed for at stabilisere regionen på det strategiske niveau – om end USA reelt ikke kan hindre små...

  13. Demystifying the GMAT: Computer-Based Testing Terms

    Science.gov (United States)

    Rudner, Lawrence M.

    2012-01-01

    Computer-based testing can be a powerful means to make all aspects of test administration not only faster and more efficient, but also more accurate and more secure. While the Graduate Management Admission Test (GMAT) exam is a computer adaptive test, there are other approaches. This installment presents a primer of computer-based testing terms.

  14. Harnessing the Flexibility of Thermostatic Loads in Microgrids with Solar Power Generation

    Directory of Open Access Journals (Sweden)

    Rosa Morales González

    2016-07-01

    Full Text Available This paper presents a demand response (DR framework that intertwines thermodynamic building models with a genetic algorithm (GA-based optimization method. The framework optimizes heating/cooling schedules of end-users inside a business park microgrid with local distributed generation from renewable energy sources (DG-RES based on two separate objectives: net load minimization and electricity cost minimization. DG-RES is treated as a curtailable resource in anticipation of future scenarios where the infeed of DG-RES to the regional distribution network could be limited. We test the DR framework with a case study of a refrigerated warehouse and an office building located in a business park with local PV generation. Results show the technical potential of the DR framework in harnessing the flexibility of the thermal masses from end-user sites in order to: (1 reduce the energy exchange at the point of connection; (2 reduce the cost of electricity for the microgrid end-users; and (3 increase the local utilization of DG-RES in cases where DG-RES exports to the grid are restricted. The results of this work can aid end-users and distribution network operators to reduce energy costs and energy consumption.

  15. A semistatic microplate-based phytotoxicity test

    Energy Technology Data Exchange (ETDEWEB)

    Radetski, C.M.; Ferard, J.F. (Univ. de Metz (France). Centre des Sciences de l' Environnement); Blaise, C. (Environment Canada, Longueuil, Quebec (Canada))

    1995-02-01

    A novel phytotoxicity test is described herein that employs a microplate equipped with membrane-bottomed wells. This MultiScreen[trademark] (Millipore Corp., Bedford, MA) microplate allows performance of a semistatic algal test, in which test medium is renewed periodically. With such a design, the algal test becomes comparable to other short-term tests used to evaluate chronic toxicity of chemicals and effluents. The EC50s obtained for Cu[sup 2+], Cd[sup 2+], Cr[sup 6+], atrazine, and one leachate sample (municipal sludge incinerator residue) with static and semistatic algal microplate tests were compared in this study. The semistatic microplate test revealed greater sensitivity than did the static microplate test.

  16. Web-Based Testing: Exploring the Relationship between Hardware Usability and Test Performance

    Science.gov (United States)

    Huff, Kyle; Cline, Melinda; Guynes, Carl S.

    2012-01-01

    Web-based testing has recently become common in both academic and professional settings. A web-based test is administered through a web browser. Individuals may complete a web-based test at nearly any time and at any place. In addition, almost any computer lab can become a testing center. It is important to understand the environmental issues that…

  17. School-Based Intervention for Test Anxiety

    Science.gov (United States)

    Yeo, Lay See; Goh, Valerie Grace; Liem, Gregory Arief D.

    2016-01-01

    Background: With children today being tested at younger ages, test anxiety has an earlier onset age. There is relatively limited research on test anxiety management programs with elementary school children. The theoretical basis for this nonrandomized pre-post intervention study is grounded in cognitive and behavioral interventions for test…

  18. Environmental testing of CIS based modules

    Energy Technology Data Exchange (ETDEWEB)

    Willett, D.

    1995-11-01

    This report describes environmental testing of Siemen`s CIS modules. Charts and diagrams are presented on data concerning: temporary power loss of laminated mini-modules; the 50 thermal cycle test; the 10 humidity freeze cycle test; results after 1000 hours of exposure to damp heat; and interconnect test structures in damp heat testing. It is concluded that moisture ingress causes permanent increases in the series resistance of modules, and that improved packaging is needed for better high humidity reliability. Also, dry dark heat caused temporary power losses which were recovered in sunlight.

  19. Validity of selected cardiovascular field-based test among Malaysian ...

    African Journals Online (AJOL)

    Based on emerge obese problem among Malaysian, this research is formulated to validate published tests among healthy female adult. Selected test namely; 20 meter multi-stage shuttle run, 2.4km run test, 1 mile walk test and Harvard Step test were correlated with laboratory test (Bruce protocol) to find the criterion validity ...

  20. Harnessing the electromagnetic absorptions of metamaterials for positive applications

    Science.gov (United States)

    Xiang, Yuanjiang; Zou, Yanhong; Luo, Hailu; Dai, Xiaoyu; Wen, Shuangchun; Fan, Dianyuan

    2010-08-01

    Absorption or loss is inevitable for the metal-based metamaterials (MMs) due to the intrinsic loss of the metal, and constitutes a major hurdle to the practical realization of most applications such as a sub-wavelength lens. Thus, to reduce the losses becomes one of the major challenges in the MM field. However, the inevitable loss can also be harnessed to take a positive role in the applications of MMs such as stealth technology or other types of cloaking devices. In this presentation, after a brief review of the advances in MMs-based absorbers, we present several schemes to fulfill the desired electromagnetic absorption properties, both linear and nonlinear. For linear absorption, we have experimentally demonstrated that the absorption performance of an ordinary microwave absorbing material can be evidently improved by using the electric resonance resulting from an array of subwavelength metallic circuit elements. For nonlinear absorption, we show theoretically that the active linear magnetic permeability induces a nonlinear absorption, similar to the two-photon absorption (TPA), of electric field in a lossy MM with a Kerr-type nonlinear polarization.

  1. Neutron Sources for Standard-Based Testing

    Energy Technology Data Exchange (ETDEWEB)

    Radev, Radoslav [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); McLean, Thomas [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2014-11-10

    The DHS TC Standards and the consensus ANSI Standards use 252Cf as the neutron source for performance testing because its energy spectrum is similar to the 235U and 239Pu fission sources used in nuclear weapons. An emission rate of 20,000 ± 20% neutrons per second is used for testing of the radiological requirements both in the ANSI standards and the TCS. Determination of the accurate neutron emission rate of the test source is important for maintaining consistency and agreement between testing results obtained at different testing facilities. Several characteristics in the manufacture and the decay of the source need to be understood and accounted for in order to make an accurate measurement of the performance of the neutron detection instrument. Additionally, neutron response characteristics of the particular instrument need to be known and taken into account as well as neutron scattering in the testing environment.

  2. Biglan Model Test Based on Institutional Diversity.

    Science.gov (United States)

    Roskens, Ronald W.; Creswell, John W.

    The Biglan model, a theoretical framework for empirically examining the differences among subject areas, classifies according to three dimensions: adherence to common set of paradigms (hard or soft), application orientation (pure or applied), and emphasis on living systems (life or nonlife). Tests of the model are reviewed, and a further test is…

  3. Application Layer Definition and Analyses of Controller Area Network Bus for Wire Harness Assembly Machine

    OpenAIRE

    Guo, Hui; Jiang, Ying

    2006-01-01

    With the feature of multi-master bus access, nondestructive contention-based arbitration and flexible configuration, Controller Area Network (CAN) bus is applied into the control system of Wire Harness Assembly Machine (WHAM). To accomplish desired goal, the specific features of the CAN bus is analyzed by compared with other field buses and the functional performances in the CAN bus system of WHAM is discussed. Then the application layer planning of CAN bus for dynamic priority is presented. ...

  4. Computer-Aided Test Flow in Core-Based Design

    NARCIS (Netherlands)

    Zivkovic, V.; Tangelder, R.J.W.T.; Kerkhoff, Hans G.

    2000-01-01

    This paper copes with the efficient test-pattern generation in a core-based design. A consistent Computer-Aided Test (CAT) flow is proposed based on the required core-test strategy. It generates a test-pattern set for the embedded cores with high fault coverage and low DfT area overhead. The CAT

  5. Analysing Test-Takers' Views on a Computer-Based Speaking Test

    Science.gov (United States)

    Amengual-Pizarro, Marian; García-Laborda, Jesús

    2017-01-01

    This study examines test-takers' views on a computer-delivered speaking test in order to investigate the aspects they consider most relevant in technology-based oral assessment, and to explore the main advantages and disadvantages computer-based tests may offer as compared to face-to-face speaking tests. A small-scale open questionnaire was…

  6. Likelihood based testing for no fractional cointegration

    DEFF Research Database (Denmark)

    Lasak, Katarzyna

    We consider two likelihood ratio tests, so-called maximum eigenvalue and trace tests, for the null of no cointegration when fractional cointegration is allowed under the alternative, which is a first step to generalize the so-called Johansen's procedure to the fractional cointegration case....... The standard cointegration analysis only considers the assumption that deviations from equilibrium can be integrated of order zero, which is very restrictive in many cases and may imply an important loss of power in the fractional case. We consider the alternative hypotheses with equilibrium deviations...... that can be mean reverting with order of integration possibly greater than zero. Moreover, the degree of fractional cointegration is not assumed to be known, and the asymptotic null distribution of both tests is found when considering an interval of possible values. The power of the proposed tests under...

  7. Optimal Test Design with Rule-Based Item Generation

    Science.gov (United States)

    Geerlings, Hanneke; van der Linden, Wim J.; Glas, Cees A. W.

    2013-01-01

    Optimal test-design methods are applied to rule-based item generation. Three different cases of automated test design are presented: (a) test assembly from a pool of pregenerated, calibrated items; (b) test generation on the fly from a pool of calibrated item families; and (c) test generation on the fly directly from calibrated features defining…

  8. Optimal test design with rule-based item generation

    NARCIS (Netherlands)

    Geerlings, Hanneke; van der Linden, Willem J.; Glas, Cornelis A.W.

    2013-01-01

    Optimal test-design methods are applied to rule-based item generation. Three different cases of automated test design are presented: (a) test assembly from a pool of pregenerated, calibrated items; (b) test generation on the fly from a pool of calibrated item families; and (c) test generation on the

  9. Issues in Competency-Based Testing.

    Science.gov (United States)

    Benner, Patricia

    1982-01-01

    Presents three areas of skilled performance as examples of an interpretive approach to the identification of nursing competencies. Also examines competency measurement strategies, definitions of competency-based education and examination, limits of competency-based education, and alternative approaches. (CT)

  10. Toxic but drank: gustatory aversive compounds induce post-ingestional malaise in harnessed honeybees.

    Directory of Open Access Journals (Sweden)

    Ainara Ayestaran

    Full Text Available BACKGROUND: Deterrent substances produced by plants are relevant due to their potential toxicity. The fact that most of these substances have an unpalatable taste for humans and other mammals contrasts with the fact that honeybees do not reject them in the range of concentrations in which these compounds are present in flower nectars. Here we asked whether honeybees detect and ingest deterrent substances and whether these substances are really toxic to them. RESULTS: We show that pairing aversive substances with an odor retards learning of this odor when it is subsequently paired with sucrose. Harnessed honeybees in the laboratory ingest without reluctance a considerable volume (20 µl of various aversive substances, even if some of them induce significant post-ingestional mortality. These substances do not seem, therefore, to be unpalatable to harnessed bees but induce a malaise-like state that in some cases results in death. Consistently with this finding, bees learning that one odor is associated with sugar, and experiencing in a subsequent phase that the sugar was paired with 20 µl of an aversive substance (devaluation phase, respond less than control bees to the odor and the sugar. Such stimulus devaluation can be accounted for by the malaise-like state induced by the aversive substances. CONCLUSION: Our results indicate that substances that taste bitter to humans as well as concentrated saline solutions base their aversive effect on the physiological consequences that their ingestion generates in harnessed bees rather than on an unpalatable taste. This conclusion is only valid for harnessed bees in the laboratory as freely-moving bees might react differently to aversive compounds could actively reject aversive substances. Our results open a new possibility to study conditioned taste aversion based on post-ingestional malaise and thus broaden the spectrum of aversive learning protocols available in honeybees.

  11. TREAT (TREe-based Association Test)

    Science.gov (United States)

    TREAT is an R package for detecting complex joint effects in case-control studies. The test statistic is derived from a tree-structure model by recursive partitioning the data. Ultra-fast algorithm is designed to evaluate the significance of association be

  12. Applying Motion Constraints Based on Test Data

    Science.gov (United States)

    Burlone, Michael

    2014-01-01

    MSC ADAMS is a simulation software that is used to analyze multibody dynamics. Using user subroutines, it is possible to apply motion constraints to the rigid bodies so that they match the motion profile collected from test data. This presentation describes the process of taking test data and passing it to ADAMS using user subroutines, and uses the Morpheus free-flight 4 test as an example of motion data used for this purpose. Morpheus is the name of a prototype lander vehicle built by NASA that serves as a test bed for various experimental technologies (see backup slides for details) MSC.ADAMS"TM" is used to play back telemetry data (vehicle orientation and position) from each test as the inputs to a 6-DoF general motion constraint (details in backup slides) The MSC.ADAMS"TM" playback simulations allow engineers to examine and analyze flight trajectory as well as observe vehicle motion from any angle and at any playback speed. This facilitates the development of robust and stable control algorithms, increasing reliability and reducing development costs of this developmental engine The simulation also incorporates a 3D model of the artificial hazard field, allowing engineers to visualize and measure performance of the developmental autonomous landing and hazard avoidance technology ADAMS is a multibody dynamics solver. It uses forces, constraints, and mass properties to numerically integrate equations of motion. The ADAMS solver will ask the motion subroutine for position, velocity, and acceleration values at various time steps. Those values must be continuous over the whole time domain. Each degree of freedom in the telemetry data can be examined separately; however, linear interpolation of the telemetry data is invalid, since there will be discontinuities in velocity and acceleration.

  13. Kernel-based tests for joint independence

    DEFF Research Database (Denmark)

    Pfister, Niklas; Bühlmann, Peter; Schölkopf, Bernhard

    2018-01-01

    the $d$-dimensional joint distribution and the product of the marginals into a reproducing kernel Hilbert space and define the $d$-variable Hilbert-Schmidt independence criterion (dHSIC) as the squared distance between the embeddings. In the population case, the value of dHSIC is zero if and only......We investigate the problem of testing whether $d$ random variables, which may or may not be continuous, are jointly (or mutually) independent. Our method builds on ideas of the two variable Hilbert-Schmidt independence criterion (HSIC) but allows for an arbitrary number of variables. We embed...

  14. Test Review: Test of English as a Foreign Language[TM]--Internet-Based Test (TOEFL iBT[R])

    Science.gov (United States)

    Alderson, J. Charles

    2009-01-01

    In this article, the author reviews the TOEFL iBT which is the latest version of the TOEFL, whose history stretches back to 1961. The TOEFL iBT was introduced in the USA, Canada, France, Germany and Italy in late 2005. Currently the TOEFL test is offered in two testing formats: (1) Internet-based testing (iBT); and (2) paper-based testing (PBT).…

  15. Testing for Statistical Discrimination based on Gender

    OpenAIRE

    Lesner, Rune Vammen

    2016-01-01

    This paper develops a model which incorporates the two most commonly cited strands of the literature on statistical discrimination, namely screening discrimination and stereotyping. The model is used to provide empirical evidence of statistical discrimination based on gender in the labour market. It is shown that the implications of both screening discrimination and stereotyping are consistent with observable wage dynamics. In addition, it is found that the gender wage gap decreases in tenure...

  16. Test Anxiety Analysis of Chinese College Students in Computer-Based Spoken English Test

    Science.gov (United States)

    Yanxia, Yang

    2017-01-01

    Test anxiety was a commonly known or assumed factor that could greatly influence performance of test takers. With the employment of designed questionnaires and computer-based spoken English test, this paper explored test anxiety manifestation of Chinese college students from both macro and micro aspects, and found out that the major anxiety in…

  17. Large-Scale Multiobjective Static Test Generation for Web-Based Testing with Integer Programming

    Science.gov (United States)

    Nguyen, M. L.; Hui, Siu Cheung; Fong, A. C. M.

    2013-01-01

    Web-based testing has become a ubiquitous self-assessment method for online learning. One useful feature that is missing from today's web-based testing systems is the reliable capability to fulfill different assessment requirements of students based on a large-scale question data set. A promising approach for supporting large-scale web-based…

  18. Short- and long-distance control of root development by LjHAR1 during the juvenile stage of Lotus japonicus.

    Science.gov (United States)

    Buzas, Diana Mihaela; Gresshoff, Peter Michael

    2007-04-01

    The autoregulation of nodulation (AON) is a universal mechanism to legumes to control the extent of nodulation via a systemic circuit and if genetically altered, as in the Lotus japonicus har1-1 mutant, leads to hypernodulation and aberrant root development. Increased nodulation of har1-1 is associated with pleiotropic effects both in the absence and presence of the symbiosis. We used two different grafting techniques to investigate the control of the non-symbiotic retarded root growth phenotype of har1-1, and demonstrate that altered root growth in the non-symbiotic condition is controlled by the genotype of both the shoot and the root. Based on these results and on the Gresshoff and Delves [Plant genetic approaches to symbiotic nodulation and nitrogen fixation in legumes. Plant Gene Res 1986;3:159-206] AON model, we propose an advanced working model for control of root development by LjHAR1.

  19. Testing for Statistical Discrimination based on Gender

    DEFF Research Database (Denmark)

    Lesner, Rune Vammen

    This paper develops a model which incorporates the two most commonly cited strands of the literature on statistical discrimination, namely screening discrimination and stereotyping. The model is used to provide empirical evidence of statistical discrimination based on gender in the labour market....... It is shown that the implications of both screening discrimination and stereotyping are consistent with observable wage dynamics. In addition, it is found that the gender wage gap decreases in tenure but increases in job transitions and that the fraction of women in high-ranking positions within a firm does...... not affect the level of statistical discrimination by gender....

  20. Test Anxiety Analysis of Chinese College Students in Computer-based Spoken English Test

    National Research Council Canada - National Science Library

    Yang Yanxia

    2017-01-01

    .... With the employment of designed questionnaires and computer-based spoken English test, this paper explored test anxiety manifestation of Chinese college students from both macro and micro aspects...

  1. Harnessing big data to meet the Sustainable Development Goals ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Harnessing big data to meet the Sustainable Development Goals – Building capacity in the Global South. Large volumes of complex and variable data, often called big data, promise to improve government service delivery, complement official statistics, and facilitate development in sectors such as health, urban ...

  2. Manufacture and quality control of interconnecting wire harnesses, Volume 3

    Science.gov (United States)

    1972-01-01

    The document covers interconnecting wire harnesses defined in the design standard, including type 6, enclosed in TFE heat shrink tubing; and type 7, flexible armored. Knowledge gained through experience on the Saturn 5 program coupled with recent advances in techniques, materials, and processes was incorporated into this document.

  3. Manufacture and quality control of interconnecting wire harnesses

    Science.gov (United States)

    1973-01-01

    Four-volume series of documents has been prepared as standard reference. Each volume may be used separately and covers wire and cable preparation as well as harness fabrication and installation. Series should be useful addition to libraries of manufactures of electrical and electronic equipment.

  4. Urter har mange funktioner i græsmarken

    DEFF Research Database (Denmark)

    Søegaard, Karen

    2009-01-01

    Urter etableres i græsmarken ud fra mange forskellige formål. De kan udgøre en betydende del af afgrøden, når frømængden er stor nok. Urter-arterne har meget forskellig konkurrenceevne og afgrødekvalitet. Udgivelsesdato: 14-08-09...

  5. Harnessing the potentials of youth for rural household food security ...

    African Journals Online (AJOL)

    The food security question calls for participatory approach by the major stakeholders in the rural household in agriculture Youth are veritable assets in the household because of their dynamism, adventure, ambition and innovativeness. These potentials could be harnessed for rural household food security. This paper ...

  6. 42 CFR 84.1138 - Head harnesses; minimum requirements.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Head harnesses; minimum requirements. 84.1138 Section 84.1138 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Dust, Fume...

  7. Vi har beskæftigelseskrise, ikke uddannelseskrise

    DEFF Research Database (Denmark)

    Grindsted, Thomas Skou; Skou Grindsted, Louise

    2014-01-01

    Universiteterne er for dårlige, og kandidaternes kompetencer er forkerte, derfor ender mange i arbejdsløshed, mener Danmarks Akkrediteringsinstitution, Produktivitetskommissionen og DI. Men for få år siden var der mangel på højtuddannet arbejdskraft, så måske har vi et beskæftigelsesproblem snarere...

  8. Taso Mähar : avatud vannitoaga vanalinna korter / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Modernne korter (220 m2). Sisearhitekt Taso Mähar, tema kommentaarid. Kogu korteri ulatuses on sisekujundusmaterjalidena kasutatud väärispuitu, metalli, marmorit ja klaasi. T. Mähari projekteeritud on trepp ja piirded, kamin, baarilett ja õhukesed alumiiniumraamidel mattklaasidega uksed. Ill.: I ja II korruse plaan, 8 värv. vaadet

  9. Har jeg forstået det rigtigt?

    DEFF Research Database (Denmark)

    Horsted, Mette Wenzel; Herly, Lene

    2009-01-01

    Interviews med sygeplejestuderende, der har problemer i forhold til biokemi, anatomi og fysiologi, gav indsigt i disse studerendes læringsstrategier i undervisningen. Ved bevidst at inddrage motiverende faktorer som inklusion, attitude, mening og kompetence (1), kan der skabes et læringsmiljø, hvor...

  10. Harness: Development of a multifunctional protective ship bulkhead

    NARCIS (Netherlands)

    Wal, R. van der; Meuers, R.J.C.

    2016-01-01

    HARNESS is a joint project between governments, industry and TNO with the objective to develop a multifunctional protective bulkhead for application on naval vessels. The multifunctional bulkhead aims at increasing the resilience of naval vessels, reduce damage and repair time and provide a safer

  11. Using Discussion Methods to Inspire Diversity: Harnessing Social & Cultural Capital

    Science.gov (United States)

    Raison, Brian; Gordon, Beverly

    2012-01-01

    How can you better harness the powerful social capital that exists within diverse individuals, families, businesses, and schools to make positive impacts in your community? What could you add to your next meeting--a Chamber strategic planning session, an employee wellness program, a non-profit board development--to better connect participants with…

  12. Harnessing the power of civil registration and vital statistics systems ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2018-02-27

    Harnessing the power of civil registration and vital statistics systems. A doctor speaks to a woman with her baby in Afghanistan. Graham Crouch/World Bank. Event date: February 27, 2018 to February 28, 2018. Location: IDRC. 150 Kent Street, 8th floor. Ottawa, ON. Canada. Time: 9:00am - 5:45pm. This conference will ...

  13. Harnessing Quantum Interference in Molecular Dielectric Materials.

    Science.gov (United States)

    Bergfield, Justin P; Heitzer, Henry M; Van Dyck, Colin; Marks, Tobin J; Ratner, Mark A

    2015-06-23

    We investigate the relationship between dielectric response and charge transport in molecule-based materials operating in the quantum coherent regime. We find that quantum interference affects these observables differently, for instance, allowing current passing through certain materials to be reduced by orders of magnitude without affecting dielectric behavior (or band gap). As an example, we utilize ab initio electronic structure theory to calculate conductance and dielectric constants of cross-conjugated anthraquinone (AQ)-based and linearly conjugated anthracene (AC)-based materials. In spite of having nearly equal fundamental gaps, electrode bonding configurations, and molecular dimensions, we find a ∼1.7 order of magnitude (∼50-fold) reduction in the conductance of the AQ-based material relative to the AC-based material, a value in close agreement with recent measurements, while the calculated dielectric constants of both materials are nearly identical. From these findings, we propose two molecular materials in which quantum interference is used to reduce leakage currents across a ∼25 Å monolayer gap with dielectric constants larger than 4.5.

  14. Wind turbine blade testing system using base excitation

    Science.gov (United States)

    Cotrell, Jason; Thresher, Robert; Lambert, Scott; Hughes, Scott; Johnson, Jay

    2014-03-25

    An apparatus (500) for fatigue testing elongate test articles (404) including wind turbine blades through forced or resonant excitation of the base (406) of the test articles (404). The apparatus (500) includes a testing platform or foundation (402). A blade support (410) is provided for retaining or supporting a base (406) of an elongate test article (404), and the blade support (410) is pivotally mounted on the testing platform (402) with at least two degrees of freedom of motion relative to the testing platform (402). An excitation input assembly (540) is interconnected with the blade support (410) and includes first and second actuators (444, 446, 541) that act to concurrently apply forces or loads to the blade support (410). The actuator forces are cyclically applied in first and second transverse directions. The test article (404) responds to shaking of its base (406) by oscillating in two, transverse directions (505, 507).

  15. DLP™-based dichoptic vision test system

    Science.gov (United States)

    Woods, Russell L.; Apfelbaum, Henry L.; Peli, Eli

    2010-01-01

    It can be useful to present a different image to each of the two eyes while they cooperatively view the world. Such dichoptic presentation can occur in investigations of stereoscopic and binocular vision (e.g., strabismus, amblyopia) and vision rehabilitation in clinical and research settings. Various techniques have been used to construct dichoptic displays. The most common and most flexible modern technique uses liquid-crystal (LC) shutters. When used in combination with cathode ray tube (CRT) displays, there is often leakage of light from the image intended for one eye into the view of the other eye. Such interocular crosstalk is 14% even in our state of the art CRT-based dichoptic system. While such crosstalk may have minimal impact on stereo movie or video game experiences, it can defeat clinical and research investigations. We use micromirror digital light processing (DLP™) technology to create a novel dichoptic visual display system with substantially lower interocular crosstalk (0.3% remaining crosstalk comes from the LC shutters). The DLP system normally uses a color wheel to display color images. Our approach is to disable the color wheel, synchronize the display directly to the computer's sync signal, allocate each of the three (former) color presentations to one or both eyes, and open and close the LC shutters in synchrony with those color events.

  16. Harnessing Intellectual Property for Development: Some Thoughts ...

    African Journals Online (AJOL)

    Such a framework would be the lens through which contested IP issues may be resolved and upon which national IP policy and legislation might be based. The paper begins by highlighting the inherent tensions in IP, which are caused by the various stakeholder interests that this body of law seeks to balance, and by the ...

  17. Gamifying quantum research: harnessing human intuition

    Science.gov (United States)

    Sherson, Jacob

    In the emerging field of citizen science ordinary citizens have already contributed to research in as diverse fields as astronomy, protein and RNA folding, and neuron mapping by playing online games. In the www.scienceathome.org project, we have extended this democratized research to the realm of quantum physics by gamifying a class of challenges related to optimization of gate operations in a quantum computer. The games have been played by more than 150,000 players and perhaps surprisingly we observe that a large fraction of the players outperform state-of-the-art optimization algorithms. With a palette of additional games within cognitive science, behavioral economics, and corporate innovation we investigate the general features of individual and collaborative problem solving to shed additional light on the process of human intuition and innovation and potentially develop novel models of artificial intelligence. We have also developed and tested in classrooms educational games within classical and quantum physics and mathematics at high-school and university level. The games provide individualized learning and enhance motivation for the core curriculum by actively creating links to modern research challenges, see eg. Finally, we have recently launched our new democratic lab: an easily accessible remote interface for our ultra-cold atoms experiment allowing amateur scientists, students, and research institutions world-wide to perform state-of-the-art quantum experimentation. In first tests, nearly a thousand players helped optimize the production of our BEC and discovered novel efficient strategies.

  18. Observation-Based Modeling for Model-Based Testing

    NARCIS (Netherlands)

    Kanstrén, T.; Piel, E.; Gross, H.G.

    2009-01-01

    One of the single most important reasons that modeling and modelbased testing are not yet common practice in industry is the perceived difficulty of making the models up to the level of detail and quality required for their automated processing. Models unleash their full potential only through

  19. Factor Structure of the TOEFL Internet-Based Test

    Science.gov (United States)

    Sawaki, Yasuyo; Stricker, Lawrence J.; Oranje, Andreas H.

    2009-01-01

    This construct validation study investigated the factor structure of the Test of English as a Foreign Language[TM] Internet-based test (TOEFL[R] iBT). An item-level confirmatory factor analysis was conducted for a test form completed by participants in a field study. A higher-order factor model was identified, with a higher-order general factor…

  20. Home-based HIV counselling and testing in Western Kenya ...

    African Journals Online (AJOL)

    Background. Objective: To describe our experience with the feasibility and acceptance of home-based HIV counselling and testing (HBCT) in two large, rural, administrative divisions of western Kenya. Design: Setting: Results: Conclusion. : Home-based HIV counselling and testing was feasible among this rural population ...

  1. An Overview of Innovative Computer-Based Testing

    NARCIS (Netherlands)

    Klerk, Sebastiaan; Eggen, Theodorus Johannes Hendrikus Maria; Veldkamp, Bernard P.

    2012-01-01

    Driven by the technological revolution, computer-based testing (CBT) has witnessed an explosive rise the last decades, in both psychological and educational assessment. Many paper-and-pencil tests now have a computer-based equivalent. Innovations in CBT are almost innumerable, and innovative and new

  2. Technology-Based Classroom Assessments: Alternatives to Testing

    Science.gov (United States)

    Salend, Spencer J.

    2009-01-01

    Although many teachers are using new technologies to differentiate instruction and administer tests, educators are also employing a range of technology-based resources and strategies to implement a variety of classroom assessments as alternatives to standardized and teacher-made testing. Technology-based classroom assessments focus on the use of…

  3. Security Considerations and Recommendations in Computer-Based Testing

    Directory of Open Access Journals (Sweden)

    Saleh M. Al-Saleem

    2014-01-01

    Full Text Available Many organizations and institutions around the globe are moving or planning to move their paper-and-pencil based testing to computer-based testing (CBT. However, this conversion will not be the best option for all kinds of exams and it will require significant resources. These resources may include the preparation of item banks, methods for test delivery, procedures for test administration, and last but not least test security. Security aspects may include but are not limited to the identification and authentication of examinee, the risks that are associated with cheating on the exam, and the procedures related to test delivery to the examinee. This paper will mainly investigate the security considerations associated with CBT and will provide some recommendations for the security of these kinds of tests. We will also propose a palm-based biometric authentication system incorporated with basic authentication system (username/password in order to check the identity and authenticity of the examinee.

  4. Major Range and Test Facility Base Summary of Capabilities.

    Science.gov (United States)

    1983-06-01

    V:ISHAM LINDER Director Defense Test and Evaluation *1 DoD 3200.11-D MAJOR RANGE AND TEST FACILITY BASE SUMMARY OF CAPABILITIES TABLE OF CONTENTS White...suitable for zero g testing and rocket plume signature studies. TYPICAL PROJECTS SUPPORTED B-i and F-15/16 Air-Launched Cruise Missile Global Position...rocket plumes , trucks, and other aerospace and ground-based objects. The RATSCAT facility is isolated physically and electromagnetically by its

  5. A comparison of test statistics for the recovery of rapid growth-based enumeration tests

    NARCIS (Netherlands)

    van den Heuvel, Edwin R.; IJzerman-Boon, Pieta C.

    This paper considers five test statistics for comparing the recovery of a rapid growth-based enumeration test with respect to the compendial microbiological method using a specific nonserial dilution experiment. The finite sample distributions of these test statistics are unknown, because they are

  6. Using the noninformative families in family-based association tests : A powerful new testing strategy

    NARCIS (Netherlands)

    Lange, C; DeMeo, D; Silverman, EK; Weiss, ST; Laird, NM

    2003-01-01

    For genetic association studies with multiple phenotypes, we propose a new strategy for multiple testing with family-based association tests (FBATs). The strategy increases the power by both using all available family data and reducing the number of hypotheses tested while being robust against

  7. Harnessing Context for Vandalism Detection in Wikipedia

    Directory of Open Access Journals (Sweden)

    Lakshmish Ramaswamy

    2014-05-01

    Full Text Available The importance of collaborative social media (CSM applications such as Wikipedia to modern free societies can hardly be overemphasized. By allowing end users to freely create and edit content, Wikipedia has greatly facilitated democratization of information. However, over the past several years, Wikipedia has also become susceptible to vandalism, which has adversely affected its information quality. Traditional vandalism detection techniques that rely upon simple textual features such as spammy or abusive words have not been very effective in combating sophisticated vandal attacks that do not contain common vandalism markers. In this paper, we propose a context-based vandalism detection framework for Wikipedia. We first propose a contextenhanced finite state model for representing the context evolution ofWikipedia articles. This paper identifies two distinct types of context that are potentially valuable for vandalism detection, namely content-context and contributor-context. The distinguishing powers of these contexts are discussed by providing empirical results. We design two novel metrics for measuring how well the content-context of an incoming edit fits into the topic and the existing content of a Wikipedia article. We outline machine learning-based vandalism identification schemes that utilize these metrics. Our experiments indicate that utilizing context can substantially improve vandalism detection accuracy.

  8. Not used to public transport any longer. A study about transport service based on needs and requirements in Siljansnaes; Man har vant sig av med kollektivtrafik. En studie om transportservice baserad paa behov och vanor i Siljansnaes

    Energy Technology Data Exchange (ETDEWEB)

    Warsen, Lisa

    2000-05-01

    The goal of the transport policy is that every citizen shall have a transport service on a reasonable level. In sparsely populated areas the public transport service is on a low level and many groups without a private car will have small possibilities to travel to different activities. Siljansnaes, with nearly 2000 citizens, is a small region in the community Leksand in Dalarna where the transport problem have been more tangible. The aim of this project has been to create a transport system more based on the needs and requirements. Also the people who lives in Siljansnaes in their leisure times are a part in the project. They are almost as many as the permanent living ones. The result also has been built on the goal of a higher care of the environment. The transport solution contains; village-bus, car-pooling, changed price system for public transport, but also a partnership between the citizens, the community and the regional transport company (Dalatrafik). The project as a process has the goal that the people in Siljansnaes should take part of the solution and the responsibility for the operation of the system.

  9. Harnessing Nanoparticles for Immunomodulation and Vaccines

    Directory of Open Access Journals (Sweden)

    Ariane C. Gomes

    2017-02-01

    Full Text Available The first successful use of nanoparticles (NPs for vaccination was reported almost 40 years ago with a virus-like particle-based vaccine against Hepatitis B. Since then, the term NP has been expanded to accommodate a large number of novel nano-sized particles engineered from a range of materials. The great interest in NPs is likely not only a result of the two successful vaccines against hepatitis B and Human Papilloma Virus (HPV that use this technology, but also due to the versatility of those small-sized particles, as indicated by the wide range of applications reported so far, ranging from medicinal and cosmetics to purely technical applications. In this review, we will focus on the use of NPs, especially virus-like particles (VLPs, in the field of vaccines and will discuss their employment as vaccines, antigen display platforms, adjuvants and drug delivery systems.

  10. Harnessing the fiber fuse for sensing applications.

    Science.gov (United States)

    Lin, Guei-Ru; Baiad, Mohamad Diaa; Gagne, Mathieu; Liu, Wen-Fung; Kashyap, Raman

    2014-04-21

    A simple refractive index sensor based on a small section of fiber damaged by the fiber fuse is proposed and demonstrated with a sensitivity of 350.58 nm/refractive index unit (RIU). For comparison, a hetero-core structure fiber sensor composed of a short no-core fiber (NCF) sandwiched between two pieces of single-mode fibers is demonstrated with a sensitivity of 157.29 nm/RIU. The fiber fuse technique can allow mass production of sensors by incorporating small sections of the damaged fiber of any type into each device. We believe this is the first application of the periodic damage tracks in optical fibers formed by the fiber fuse.

  11. Harnessing natural diversity to probe metabolic pathways.

    Directory of Open Access Journals (Sweden)

    Oliver R Homann

    2005-12-01

    Full Text Available Analyses of cellular processes in the yeast Saccharomyces cerevisiae rely primarily upon a small number of highly domesticated laboratory strains, leaving the extensive natural genetic diversity of the model organism largely unexplored and unexploited. We asked if this diversity could be used to enrich our understanding of basic biological processes. As a test case, we examined a simple trait: the utilization of di/tripeptides as nitrogen sources. The capacity to import small peptides is likely to be under opposing selective pressures (nutrient utilization versus toxin vulnerability and may therefore be sculpted by diverse pathways and strategies. Hitherto, dipeptide utilization in S. cerevisiae was solely ascribed to the activity of a single protein, the Ptr2p transporter. Using high-throughput phenotyping and several genetically diverse strains, we identified previously unknown cellular activities that contribute to this trait. We find that the Dal5p allantoate/ureidosuccinate permease is also capable of facilitating di/tripeptide transport. Moreover, even in the absence of Dal5p and Ptr2p, an additional activity--almost certainly the periplasmic asparaginase II Asp3p--facilitates the utilization of dipeptides with C-terminal asparagine residues by a different strategy. Another, as-yet-unidentified activity enables the utilization of dipeptides with C-terminal arginine residues. The relative contributions of these activities to the utilization of di/tripeptides vary among the strains analyzed, as does the vulnerability of these strains to a toxic dipeptide. Only by sampling the genetic diversity of multiple strains were we able to uncover several previously unrecognized layers of complexity in this metabolic pathway. High-throughput phenotyping facilitates the rapid exploration of the molecular basis of biological complexity, allowing for future detailed investigation of the selective pressures that drive microbial evolution.

  12. Beam-Based Alignment in CTF3 Test Beam Line

    OpenAIRE

    Sterbini, G; Dӧbert, S; Marín, E.; Lillestol, RL; Schulte, D.; Adli, E.

    2012-01-01

    The CLIC linear collider is based on the two beams acceleration scheme. During acceleration of the colliding beams, the drive beam suffers a large build up on its energy spread. In order to efficiently transport such a beam, beam-based alignment techniques together with tight prealignment tolerances are crucial. To evaluate the performance of these steering algorithms, a beam-based steering campaign has been conducted at the Test Beam Line of the CLIC Test Facility. In the following we presen...

  13. Harnessing Endogenous Systems for Cancer Therapy

    DEFF Research Database (Denmark)

    Klauber, Thomas Christopher Bogh

    In the recent decade, two strategies in particular have attracted attention due to the prospect of significantly improving cancer treatment: Gene silencing therapy and immunotherapy. Both strategies work by manipulating endogenous mechanisms and theoretically promise very strong effect on the dis......In the recent decade, two strategies in particular have attracted attention due to the prospect of significantly improving cancer treatment: Gene silencing therapy and immunotherapy. Both strategies work by manipulating endogenous mechanisms and theoretically promise very strong effect...... immunotherapy (Project II). Transfer into the clinic of therapies based on gene silencing by siRNA delivered by synthetic vectors has yet to happen. A major reason is the lack of efficiency in the delivery process, partly due to insufficient understanding of cellular uptake and processing of the si...... to the conventional PEIs. However, lipid conjugation did not sufficiently reduce the inherent toxicity associated with high molecular weight PEI, and lipid conjugation of bPEI did also not change the ability of bPEI to affect lysosomal pH as a function of time. In contrast to gene silencing therapy, cancer...

  14. Harnessing Solute Carrier Transporters for Precision Oncology.

    Science.gov (United States)

    Nyquist, Michael D; Prasad, Bhagwat; Mostaghel, Elahe A

    2017-03-28

    Solute Carrier (SLC) transporters are a large superfamily of transmembrane carriers involved in the regulated transport of metabolites, nutrients, ions and drugs across cellular membranes. A subset of these solute carriers play a significant role in the cellular uptake of many cancer therapeutics, ranging from chemotherapeutics such as antimetabolites, topoisomerase inhibitors, platinum-based drugs and taxanes to targeted therapies such as tyrosine kinase inhibitors. SLC transporters are co-expressed in groups and patterns across normal tissues, suggesting they may comprise a coordinated regulatory circuit serving to mediate normal tissue functions. In cancer however, there are dramatic changes in expression patterns of SLC transporters. This frequently serves to feed the increased metabolic demands of the tumor cell for amino acids, nucleotides and other metabolites, but also presents a therapeutic opportunity, as increased transporter expression may serve to increase intracellular concentrations of substrate drugs. In this review, we examine the regulation of drug transporters in cancer and how this impacts therapy response, and discuss novel approaches to targeting therapies to specific cancers via tumor-specific aberrations in transporter expression. We propose that among the oncogenic changes in SLC transporter expression there exist emergent vulnerabilities that can be exploited therapeutically, extending the application of precision medicine from tumor-specific drug targets to tumor-specific determinants of drug uptake.

  15. Cross-Mode Comparability of Computer-Based Testing (CBT) versus Paper-Pencil Based Testing (PPT): An Investigation of Testing Administration Mode among Iranian Intermediate EFL Learners

    Science.gov (United States)

    Khoshsima, Hooshang; Hosseini, Monirosadat; Toroujeni, Seyyed Morteza Hashemi

    2017-01-01

    Advent of technology has caused growing interest in using computers to convert conventional paper and pencil-based testing (Henceforth PPT) into Computer-based testing (Henceforth CBT) in the field of education during last decades. This constant promulgation of computers to reshape the conventional tests into computerized format permeated the…

  16. HARNESSING THE CHEMISTRY OF CO2

    Energy Technology Data Exchange (ETDEWEB)

    Louie, Janis

    2010-05-11

    Our research program is broadly focused on activating CO{sub 2} through the use of organic and organometallic based catalysts. Some of our methods have centered on annulation reactions of unsaturated hydrocarbons (and carbonyl substrates) to provide a diverse array of carbocycles and heterocycles. We use a combination of catalyst discovery and optimization in conjunction with classical physical organic chemistry to elucidate the key mechanistic features of the cycloaddition reactions such that the next big advances in catalyst development can be made. Key to all of our cycloaddition reactions is the use of a sterically hindered, electron donating N heterocyclic carbene (NHC) ligand, namely IPr (or SIPr), in conjunction with a low valent nickel pre-catalyst. The efficacy of this ligand is two-fold: (1) the high {delta}-donating ability of the NHC increases the nucleophilicity of the metal center which thereby facilitates interaction with the electrophilic carbonyl and (2) the steric hindrance prevents an otherwise competitive side reaction involving only the alkyne substrate. Such a system has allowed for the facile cycloaddition to prepare highly functionalized pyrones, pyridones, pyrans, as well as novel carbocycles. Importantly, all reactions proceed under extremely mild conditions (room temperature, atmospheric pressures, and short reaction times), require only catalytic amounts of Ni/NHC and readily available starting materials, and afford annulated products in excellent yields. Our current focus revolves around understanding the fundamental processes that govern these cycloadditions such that the next big advance in the cyclization chemistry of CO{sub 2} can be made. Concurrent to our annulation chemistry is our investigation of the potential for imidazolylidenes to function as thermally-actuated CO{sub 2} sequestering and delivery agents.

  17. Uncovering Listeria monocytogenes hypervirulence by harnessing its biodiversity.

    Science.gov (United States)

    Maury, Mylène M; Tsai, Yu-Huan; Charlier, Caroline; Touchon, Marie; Chenal-Francisque, Viviane; Leclercq, Alexandre; Criscuolo, Alexis; Gaultier, Charlotte; Roussel, Sophie; Brisabois, Anne; Disson, Olivier; Rocha, Eduardo P C; Brisse, Sylvain; Lecuit, Marc

    2016-03-01

    Microbial pathogenesis studies are typically performed with reference strains, thereby overlooking within-species heterogeneity in microbial virulence. Here we integrated human epidemiological and clinical data with bacterial population genomics to harness the biodiversity of the model foodborne pathogen Listeria monocytogenes and decipher the basis of its neural and placental tropisms. Taking advantage of the clonal structure of this bacterial species, we identify clones epidemiologically associated either with food or with human central nervous system (CNS) or maternal-neonatal (MN) listeriosis. The latter clones are also most prevalent in patients without immunosuppressive comorbidities. Strikingly, CNS- and MN-associated clones are hypervirulent in a humanized mouse model of listeriosis. By integrating epidemiological data and comparative genomics, we have uncovered multiple new putative virulence factors and demonstrate experimentally the contribution of the first gene cluster mediating L. monocytogenes neural and placental tropisms. This study illustrates the exceptional power in harnessing microbial biodiversity to identify clinically relevant microbial virulence attributes.

  18. "Har andre plejebørn det som mig?"

    DEFF Research Database (Denmark)

    Warming, H.

    Bogen handler om livet som plejebarn, som det opleves af børnene selv. Den formidler resultaterne fra forskningsprojektet: "Projekt Børnetinget - et talerør for plejebørn", hvor 15 børn i familiepleje er blevet interviewet og hvor 107 nuværende og tidligere plejebørn har skrevet på hjemmesiden ww...

  19. Hammersley’s harness process: Invariant distributions and height fluctuations

    OpenAIRE

    Seppäläinen, Timo; Zhai, Yun

    2017-01-01

    We study the invariant distributions of Hammersley’s serial harness process in all dimensions and height fluctuations in one dimension. Subject to mild moment assumptions there is essentially one unique invariant distribution, and all other invariant distributions are obtained by adding harmonic functions of the averaging kernel. We identify one Gaussian case where the invariant distribution is i.i.d. Height fluctuations in one dimension obey the stochastic heat equation with additive noise (...

  20. Hello World: Harnessing social media for the Rosetta mission

    Science.gov (United States)

    Baldwin, E.; Mignone, C.; O'Flaherty, K. S.; Homfeld, A.-M.; Bauer, M.; McCaughrean, M. J.

    2015-10-01

    The European Space Agency's (ESA) comet-chasing Rosetta mission was launched in 2004, before social media became a popular tool for mainstream communication. By harnessing a range of platforms for communicating the key messages of this unprecedented space adventure as the spacecraft reached its destination ten years later, a wide range of new audiences were reached and could follow this once-in-a-lifetime mission.

  1. Dilute prothrombin time-based lupus ratio test. Integrated LA testing with recombinant tissue thromboplastin.

    Science.gov (United States)

    Liestøl, Sigurd; Jacobsen, Eva Marie; Wisløff, Finn

    2002-01-15

    The lupus ratio (LR) test is a normalized ratio of the clotting times obtained with low and high phospholipid (PL) concentrations, where the test plasma is mixed 1:1 with normal pooled plasma (NP). As an integrated, automated, and computer-assisted assay, this principle has been applied to the dilute activated partial thromboplastin time (dAPTT) and dilute Russell viper venom time (dRVVT) test systems. In this study, we used recombinant thromboplastin to develop an automated LR test based on the dilute prothrombin time (dPT). Using plasma samples from a selected group of patients (N=92) with a well-defined lupus anticoagulant (LA) status, the dPT-based LR test showed fair agreement with the dAPTT-based LR test (kappa=.60, Psensitive of the three tests. This study confirms the general validity of the LR principle and shows that the dPT-based LR test yields reproducible results. The low coefficients of variation (CV) of the LR assays, combined with a fairly low correlation among the three tests, support the assumption of antibody heterogeneity of LA-positive plasmas and the desirability of performing more than one test.

  2. Network harness: bundles of routes in public transport networks

    Science.gov (United States)

    Berche, B.; von Ferber, C.; Holovatch, T.

    2009-12-01

    Public transport routes sharing the same grid of streets and tracks are often found to proceed in parallel along shorter or longer sequences of stations. Similar phenomena are observed in other networks built with space consuming links such as cables, vessels, pipes, neurons, etc. In the case of public transport networks (PTNs) this behavior may be easily worked out on the basis of sequences of stations serviced by each route. To quantify this behavior we use the recently introduced notion of network harness. It is described by the harness distribution P(r, s): the number of sequences of s consecutive stations that are serviced by r parallel routes. For certain PTNs that we have analyzed we observe that the harness distribution may be described by power laws. These power laws indicate a certain level of organization and planning which may be driven by the need to minimize the costs of infrastructure and secondly by the fact that points of interest tend to be clustered in certain locations of a city. This effect may be seen as a result of the strong interdependence of the evolutions of both the city and its PTN. To further investigate the significance of the empirical results we have studied one- and two-dimensional models of randomly placed routes modeled by different types of walks. While in one dimension an analytic treatment was successful, the two dimensional case was studied by simulations showing that the empirical results for real PTNs deviate significantly from those expected for randomly placed routes.

  3. Design Of Computer Based Test Using The Unified Modeling Language

    Science.gov (United States)

    Tedyyana, Agus; Danuri; Lidyawati

    2017-12-01

    The Admission selection of Politeknik Negeri Bengkalis through interest and talent search (PMDK), Joint Selection of admission test for state Polytechnics (SB-UMPN) and Independent (UM-Polbeng) were conducted by using paper-based Test (PBT). Paper Based Test model has some weaknesses. They are wasting too much paper, the leaking of the questios to the public, and data manipulation of the test result. This reasearch was Aimed to create a Computer-based Test (CBT) models by using Unified Modeling Language (UML) the which consists of Use Case diagrams, Activity diagram and sequence diagrams. During the designing process of the application, it is important to pay attention on the process of giving the password for the test questions before they were shown through encryption and description process. RSA cryptography algorithm was used in this process. Then, the questions shown in the questions banks were randomized by using the Fisher-Yates Shuffle method. The network architecture used in Computer Based test application was a client-server network models and Local Area Network (LAN). The result of the design was the Computer Based Test application for admission to the selection of Politeknik Negeri Bengkalis.

  4. Field-based physiological testing of wheelchair athletes.

    Science.gov (United States)

    Goosey-Tolfrey, Victoria L; Leicht, Christof A

    2013-02-01

    The volume of literature on field-based physiological testing of wheelchair sports, such as basketball, rugby and tennis, is considerably smaller when compared with that available for individuals and team athletes in able-bodied (AB) sports. In analogy to the AB literature, it is recognized that performance in wheelchair sports not only relies on fitness, but also sport-specific skills, experience and technical proficiency. However, in contrast to AB sports, two major components contribute towards 'wheeled sports' performance, which are the athlete and the wheelchair. It is the interaction of these two that enable wheelchair propulsion and the sporting movements required within a given sport. Like any other athlete, participants of wheelchair sports are looking for efficient ways to train and/or analyse their technique and fitness to improve their performance. Consequently, laboratory and/or field-based physiological monitoring tools used at regular intervals at key time points throughout the year must be considered to help with training evaluation. The present review examines methods available in the literature to assess wheelchair sports fitness in a field-based environment, with special attention on outcome variables, validity and reliability issues, and non-physiological influences on performance. It also lays out the context of field-based testing by providing details about the Paralympic court sports and the impacts of a disability on sporting performance. Due to the limited availability of specialized equipment for testing wheelchair-dependent participants in the laboratory, the adoption of field-based testing has become the preferred option by team coaches of wheelchair athletes. An obvious advantage of field-based testing is that large groups of athletes can be tested in less time. Furthermore, athletes are tested in their natural environment (using their normal sports wheelchair set-up and floor surface), potentially making the results of such testing

  5. Design-for-test and test optimization techniques for TSV-based 3D stacked ICs

    CERN Document Server

    Noia, Brandon

    2014-01-01

    This book describes innovative techniques to address the testing needs of 3D stacked integrated circuits (ICs) that utilize through-silicon-vias (TSVs) as vertical interconnects.  The authors identify the key challenges facing 3D IC testing and present results that have emerged from cutting-edge research in this domain.  Coverage includes topics ranging from die-level wrappers, self-test circuits, and TSV probing to test-architecture design, test scheduling, and optimization.  Readers will benefit from an in-depth look at test-technology solutions that are needed to make 3D ICs a reality and commercially viable.   • Provides a comprehensive guide to the challenges and solutions for the testing of TSV-based 3D stacked ICs; • Includes in-depth explanation of key test and design-for-test technologies, emerging standards, and test- architecture and test-schedule optimizations; • Encompasses all aspects of test as related to 3D ICs, including pre-bond and post-bond test as well as the test optimizatio...

  6. Different DMRT3 Genotypes Are Best Adapted for Harness Racing and Riding in Finnhorses.

    Science.gov (United States)

    Jäderkvist Fegraeus, Kim; Johansson, Lisa; Mäenpää, Minna; Mykkänen, Anna; Andersson, Lisa S; Velie, Brandon D; Andersson, Leif; Árnason, Thorvaldur; Lindgren, Gabriella

    2015-01-01

    Previous studies showed a positive effect of the DMRT3 "gait keeper" mutation on harness racing performance in Standardbreds, French-, and Nordic trotters. The mutation has also been shown to influence riding traits in multiple breeds. This study investigated the effect of the DMRT3 mutation on harness racing performance and riding traits in Finnhorses. Finnhorses used for harness racing (n = 180) and for riding (n = 59) were genotyped for the DMRT3 mutation. For the trotters the genotypes were evaluated for association with racing performance (number of starts, victories, placings, earnings, and race times). At 3-6 years of age the AA genotype was superior compared with the CA and CC genotypes. The AA horses had a significantly higher proportion of victories (P = 1.4×10(-6)) and placings (P = 4.1×10(-7)), better race times (P = 0.01), and earned more money (P = 0.009) compared with C-horses. For the Finnhorses used for riding the owners answered a questionnaire to score how well the horse performed the gaits walk, trot, and canter on a scale from 1 to 6. These scores were tested for association with the DMRT3 genotypes. Although AA horses were more successful as racehorses, the CC and CA horses appear more adapted for classical riding disciplines. The AA horses received significantly lower gait scores compared with C-horses for the majority of gaits. Except for rhythm in extended canter (P = 0.05), there were no significant differences between CA and CC horses. This study shows that there are different optimal genotypes for different disciplines and the DMRT3 mutation clearly influences gaits and performance in Finnhorses. © The American Genetic Association. 2015. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  7. HOW TO BUILD TESTS IN THE IMITATION MODEL FOR TEST-BASED KNOWLEDGE CONTROL

    Directory of Open Access Journals (Sweden)

    Oleksandr M. Aleksieiev

    2011-02-01

    Full Text Available The principles of imitation model for knowledge test control, specifically on the perfection of the procedure of constructing a test, are developed in this model. The authors suggest taking into account the difficulty of the question when one is making a decision about including a given test question into the test. They also suggest using iterational calculations in order to create a test with the help of optimization algorithms that are used for the process of random searching. The sum of task complexity indices for such test will meet the criteria of joint value and difficulty. Detailed explanation of mathematical apparatus that is used for decision-making during the test-building process is given in the article as well as an example that demonstrates main steps of iterational calculations and mechanisms for achieving optimal test structure based on the criteria of joint value and difficulty.

  8. A single Danio rerio hars gene encodes both cytoplasmic and mitochondrial histidyl-tRNA synthetases.

    Directory of Open Access Journals (Sweden)

    Ashley L Waldron

    Full Text Available Histidyl tRNA Synthetase (HARS is a member of the aminoacyl tRNA synthetase (ARS family of enzymes. This family of 20 enzymes is responsible for attaching specific amino acids to their cognate tRNA molecules, a critical step in protein synthesis. However, recent work highlighting a growing number of associations between ARS genes and diverse human diseases raises the possibility of new and unexpected functions in this ancient enzyme family. For example, mutations in HARS have been linked to two different neurological disorders, Usher Syndrome Type IIIB and Charcot Marie Tooth peripheral neuropathy. These connections raise the possibility of previously undiscovered roles for HARS in metazoan development, with alterations in these functions leading to complex diseases. In an attempt to establish Danio rerio as a model for studying HARS functions in human disease, we characterized the Danio rerio hars gene and compared it to that of human HARS. Using a combination of bioinformatics, molecular biology, and cellular approaches, we found that while the human genome encodes separate genes for cytoplasmic and mitochondrial HARS protein, the Danio rerio genome encodes a single hars gene which undergoes alternative splicing to produce the respective cytoplasmic and mitochondrial versions of Hars. Nevertheless, while the HARS genes of humans and Danio differ significantly at the genomic level, we found that they are still highly conserved at the amino acid level, underscoring the potential utility of Danio rerio as a model organism for investigating HARS function and its link to human diseases in vivo.

  9. Model-Based GUI Testing Using Uppaal at Novo Nordisk

    DEFF Research Database (Denmark)

    H. Hjort, Ulrik; Rasmussen, Jacob Illum; Larsen, Kim Guldstrand

    2009-01-01

    This paper details a collaboration between Aalborg University and Novo Nordiskin developing an automatic model-based test generation tool for system testing of the graphical user interface of a medical device on an embedded platform. The tool takes as input an UML Statemachine model and generates...

  10. Defect-based testing of LTS digital circuits

    NARCIS (Netherlands)

    Arun, A.J.

    2006-01-01

    A Defect-Based Test (DBT) methodology for Superconductor Electronics (SCE) is presented in this thesis, so that commercial production and efficient testing of systems can be implemented in this technology in the future. In the first chapter, the features and prospects for SCE have been presented.

  11. Conceptualizing Teaching to the Test under Standards-Based Reform

    Science.gov (United States)

    Welsh, Megan E.; Eastwood, Melissa; D'Agostino, Jerome V.

    2014-01-01

    Teacher and school accountability systems based on high-stakes tests are ubiquitous throughout the United States and appear to be growing as a catalyst for reform. As a result, educators have increased the proportion of instructional time devoted to test preparation. Although guidelines for what constitutes appropriate and inappropriate test…

  12. [Study of dental model testing tool based on robot theory].

    Science.gov (United States)

    Hu, B; Song, Y; Cheng, L

    1999-09-01

    A new three dimensional testing and analysing system of dental model is discussed It is designed based on the motion theory of robots. The system is capable of not only measuring the three dimensional sizes of dental models, but also saving and outputing the tested data. The construction of the system is briefly introduced here.

  13. HEV Test Bench Based on CAN Bus Sensor Communication

    Directory of Open Access Journals (Sweden)

    Shupeng ZHAO

    2014-02-01

    Full Text Available The HEV test bench based on Controller Area Network bus was studied and developed. Control system of HEV power test bench used the CAN bus technology. The application of CAN bus technology on control system development has opened up a new research direction for domestic automobile experimental platform. The HEV power control system development work was completed, including power master controller, electric throttle controller, driving simulation platform, CAN2.0 B communication protocol procedures for formulation, CAN communication monitoring system, the simulation model based on MATLAB code automatic generation technology research, etc. Maximum absorption power of the test bench is 90 kW, the test bench top speed is 6000 r/min, the CAN communication data baud rate is 10~500 k, the conventional electric measurement parameter part precision satisfies the requirement of development of HEV. On the HEV test bench the result of regenerative braking experiment shows that the result got by the test bench was closer to the results got by outdoor road test. And the fuel consumption experiment test results show that the HEV fuel consumption and the charge-discharge character are in linear relationship. The establishment of the test platform for the evaluation of the development of hybrid electric vehicle and power provides physical simulation and test platform.

  14. On school choice and test-based accountability.

    Directory of Open Access Journals (Sweden)

    Damian W. Betebenner

    2005-10-01

    Full Text Available Among the two most prominent school reform measures currently being implemented in The United States are school choice and test-based accountability. Until recently, the two policy initiatives remained relatively distinct from one another. With the passage of the No Child Left Behind Act of 2001 (NCLB, a mutualism between choice and accountability emerged whereby school choice complements test-based accountability. In the first portion of this study we present a conceptual overview of school choice and test-based accountability and explicate connections between the two that are explicit in reform implementations like NCLB or implicit within the market-based reform literature in which school choice and test-based accountability reside. In the second portion we scrutinize the connections, in particular, between school choice and test-based accountability using a large western school district with a popular choice system in place. Data from three sources are combined to explore the ways in which school choice and test-based accountability draw on each other: state assessment data of children in the district, school choice data for every participating student in the district choice program, and a parental survey of both participants and non-participants of choice asking their attitudes concerning the use of school report cards in the district. Results suggest that choice is of benefit academically to only the lowest achieving students, choice participation is not uniform across different ethnic groups in the district, and parents' primary motivations as reported on a survey for participation in choice are not due to test scores, though this is not consistent with choice preferences among parents in the district. As such, our results generally confirm the hypotheses of choice critics more so than advocates. Keywords: school choice; accountability; student testing.

  15. CoDiagnose: Interactive software to harness collaborative diagnoses and to increase diagnostic accuracy amongst junior physicians.

    Science.gov (United States)

    McComb, Steven; Bond, Raymond R

    2015-01-01

    Many studies have been conducted that highlight the prevalence of misdiagnoses within the medical profession and the statistically poor diagnostic accuracy rates associated with junior clinicians. There is evidence that crowdsourcing and multiple medical opinions can improve the veracity of a diagnosis. This paper proposes a cloud based prototype that makes use of interactive web technologies along with the concepts of crowdsourcing and e-learning to improve diagnostic accuracy rates amongst junior doctors. Existing approaches in this field are analysed to identify potential gaps and opportunities. Sample representations of both junior and senior clinicians are surveyed to establish the feasibility of adopting collaborative diagnostics. It is theorised that the prototype developed in this work will harness the experience and knowledge of expert clinicians. The prototype is a fully responsive web-based and feature-rich interactive system that has been developed using the latest Internet technologies. It has been evaluated using usability tests and a one month long trial involving a sample of end-users. Crowdsourcing is an innovative process in its infancy but the results being produced indicate a promising future for its use within medicine. The results offer an inclination that the prototype's usage could be attributed to improved diagnostic ability. However the findings need to be replicated in larger, independent samples.

  16. Efficient p-value evaluation for resampling-based tests

    KAUST Repository

    Yu, K.

    2011-01-05

    The resampling-based test, which often relies on permutation or bootstrap procedures, has been widely used for statistical hypothesis testing when the asymptotic distribution of the test statistic is unavailable or unreliable. It requires repeated calculations of the test statistic on a large number of simulated data sets for its significance level assessment, and thus it could become very computationally intensive. Here, we propose an efficient p-value evaluation procedure by adapting the stochastic approximation Markov chain Monte Carlo algorithm. The new procedure can be used easily for estimating the p-value for any resampling-based test. We show through numeric simulations that the proposed procedure can be 100-500 000 times as efficient (in term of computing time) as the standard resampling-based procedure when evaluating a test statistic with a small p-value (e.g. less than 10( - 6)). With its computational burden reduced by this proposed procedure, the versatile resampling-based test would become computationally feasible for a much wider range of applications. We demonstrate the application of the new method by applying it to a large-scale genetic association study of prostate cancer.

  17. Evolution of a Computer-Based Testing Laboratory

    Science.gov (United States)

    Moskal, Patrick; Caldwell, Richard; Ellis, Taylor

    2009-01-01

    In 2003, faced with increasing growth in technology-based and large-enrollment courses, the College of Business Administration at the University of Central Florida opened a computer-based testing lab to facilitate administration of course examinations. Patrick Moskal, Richard Caldwell, and Taylor Ellis describe the development and evolution of the…

  18. Design, construction and testing of a base driven static inverter ...

    African Journals Online (AJOL)

    Based on the active circuit of a 50Hz astable multivibrator, a base driven static inverter has been designed, constructed and tested. Design is able to convert small amounts of dc current to their amplified ac equivalents. A conversion of 12V dc input to the usual domestic range of 220-240V ac is also derivable from the ...

  19. Web based aphasia test using service oriented architecture (SOA)

    Science.gov (United States)

    Voos, J. A.; Vigliecca, N. S.; Gonzalez, E. A.

    2007-11-01

    Based on an aphasia test for Spanish speakers which analyze the patient's basic resources of verbal communication, a web-enabled software was developed to automate its execution. A clinical database was designed as a complement, in order to evaluate the antecedents (risk factors, pharmacological and medical backgrounds, neurological or psychiatric symptoms, brain injury -anatomical and physiological characteristics, etc) which are necessary to carry out a multi-factor statistical analysis in different samples of patients. The automated test was developed following service oriented architecture and implemented in a web site which contains a tests suite, which would allow both integrating the aphasia test with other neuropsychological instruments and increasing the available site information for scientific research. The test design, the database and the study of its psychometric properties (validity, reliability and objectivity) were made in conjunction with neuropsychological researchers, who participate actively in the software design, based on the patients or other subjects of investigation feedback.

  20. Development of seismic technology and reliability based on vibration tests

    Energy Technology Data Exchange (ETDEWEB)

    Sasaki, Youichi [Nuclear Power Engineering Corp., Tokyo (Japan)

    1997-03-01

    This paper deals with some of the vibration tests and investigations on the seismic safety of nuclear power plants (NPPs) in Japan. To ensure the reliability of the seismic safety of nuclear power plants, nuclear power plants in Japan have been designed according to the Technical Guidelines for Aseismic Design of Nuclear Power Plants. This guideline has been developed based on technical date base and findings which were obtained from many vibration tests and investigations. Besides the tests for the guideline, proving tests on seismic reliability of operating nuclear power plants equipment and systems have been carried out. In this paper some vibration tests and their evaluation results are presented. They have crucially contributed to develop the guideline. (J.P.N.)

  1. Web based aphasia test using service oriented architecture (SOA)

    Energy Technology Data Exchange (ETDEWEB)

    Voos, J A [Clinical Engineering R and D Center, Universidad Tecnologica Nacional, Facultad Regional Cordoba, Cordoba (Argentina); Vigliecca, N S [Consejo Nacional de Investigaciones Cientificas y Tecnicas, CONICET, Cordoba (Argentina); Gonzalez, E A [Clinical Engineering R and D Center, Universidad Tecnologica Nacional, Facultad Regional Cordoba, Cordoba (Argentina)

    2007-11-15

    Based on an aphasia test for Spanish speakers which analyze the patient's basic resources of verbal communication, a web-enabled software was developed to automate its execution. A clinical database was designed as a complement, in order to evaluate the antecedents (risk factors, pharmacological and medical backgrounds, neurological or psychiatric symptoms, brain injury -anatomical and physiological characteristics, etc) which are necessary to carry out a multi-factor statistical analysis in different samples of patients. The automated test was developed following service oriented architecture and implemented in a web site which contains a tests suite, which would allow both integrating the aphasia test with other neuropsychological instruments and increasing the available site information for scientific research. The test design, the database and the study of its psychometric properties (validity, reliability and objectivity) were made in conjunction with neuropsychological researchers, who participate actively in the software design, based on the patients or other subjects of investigation feedback.

  2. Task based displays - rationale, design, user test and assessment

    Energy Technology Data Exchange (ETDEWEB)

    Foerdestroemmen, Nils

    2004-04-15

    The report summarizes the work that has been done on task-based displays within the Halden Reactor Project in the period 1998-2003. The development work on task-based displays was initiated in 1998, and the prototype design was reported in 1999. In 2001, four realised task displays were exposed to a user test, and the display design and user test results were reported in 2002. During 2003, the previous work was reviewed, summarised and assessed. The work presented in this report forms the basis for the future planned work on task-based displays. (Author)

  3. Testing ESL sociopragmatics development and validation of a web-based test battery

    CERN Document Server

    Roever, Carsten; Elder, Catherine

    2014-01-01

    Testing of second language pragmatics has grown as a research area but still suffers from a tension between construct coverage and practicality. In this book, the authors describe the development and validation of a web-based test of second language pragmatics for learners of English. The test has a sociopragmatic orientation and strives for a broad coverage of the construct by assessing learners'' metapragmatic judgments as well as their ability to co-construct discourse. To ensure practicality, the test is delivered online and is scored partially automatically and partially by human raters.

  4. Testing Game-Based Performance in Team-Handball.

    Science.gov (United States)

    Wagner, Herbert; Orwat, Matthias; Hinz, Matthias; Pfusterschmied, Jürgen; Bacharach, David W; von Duvillard, Serge P; Müller, Erich

    2016-10-01

    Wagner, H, Orwat, M, Hinz, M, Pfusterschmied, J, Bacharach, DW, von Duvillard, SP, and Müller, E. Testing game-based performance in team-handball. J Strength Cond Res 30(10): 2794-2801, 2016-Team-handball is a fast paced game of defensive and offensive action that includes specific movements of jumping, passing, throwing, checking, and screening. To date and to the best of our knowledge, a game-based performance test (GBPT) for team-handball does not exist. Therefore, the aim of this study was to develop and validate such a test. Seventeen experienced team-handball players performed 2 GBPTs separated by 7 days between each test, an incremental treadmill running test, and a team-handball test game (TG) (2 × 20 minutes). Peak oxygen uptake (V[Combining Dot Above]O2peak), blood lactate concentration (BLC), heart rate (HR), sprinting time, time of offensive and defensive actions as well as running intensities, ball velocity, and jump height were measured in the game-based test. Reliability of the tests was calculated using an intraclass correlation coefficient (ICC). Additionally, we measured V[Combining Dot Above]O2peak in the incremental treadmill running test and BLC, HR, and running intensities in the team-handball TG to determine the validity of the GBPT. For the test-retest reliability, we found an ICC >0.70 for the peak BLC and HR, mean offense and defense time, as well as ball velocity that yielded an ICC >0.90 for the V[Combining Dot Above]O2peak in the GBPT. Percent walking and standing constituted 73% of total time. Moderate (18%) and high (9%) intensity running in the GBPT was similar to the team-handball TG. Our results indicated that the GBPT is a valid and reliable test to analyze team-handball performance (physiological and biomechanical variables) under conditions similar to competition.

  5. Evidence-Based Guidelines to Eliminate Repetitive Laboratory Testing.

    Science.gov (United States)

    Eaton, Kevin P; Levy, Kathryn; Soong, Christine; Pahwa, Amit K; Petrilli, Christopher; Ziemba, Justin B; Cho, Hyung J; Alban, Rodrigo; Blanck, Jaime F; Parsons, Andrew S

    2017-10-16

    Routine daily laboratory testing of hospitalized patients reflects a wasteful clinical practice that threatens the value of health care. Choosing Wisely initiatives from numerous professional societies have identified repetitive laboratory testing in the face of clinical stability as low value care. Although laboratory expenditure often represents less than 5% of most hospital budgets, the impact is far-reaching given that laboratory tests influence nearly 60% to 70% of all medical decisions. Excessive phlebotomy can lead to hospital-acquired anemia, increased costs, and unnecessary downstream testing and procedures. Efforts to reduce the frequency of laboratory orders can improve patient satisfaction and reduce cost without negatively affecting patient outcomes. To date, numerous interventions have been deployed across multiple institutions without a standardized approach. Health care professionals and administrative leaders should carefully strategize and optimize efforts to reduce daily laboratory testing. This review presents an evidence-based implementation blueprint to guide teams aimed at improving appropriate routine laboratory testing among hospitalized patients.

  6. Investigating Recent Testing among MSM: Results from Community-Based HIV Rapid Testing Attendees in France

    Directory of Open Access Journals (Sweden)

    Nicolas Lorente

    2013-01-01

    Full Text Available Background. We aimed to identify factors associated with recent HIV testing in MSM who attended two experimental community-based and nonmedicalized voluntary counselling and testing programmes (CB-VCT targeting MSM in France. Methods. This analysis was based on data collected in 2009–2011 through a self-administered pretesting questionnaire. An index measuring the level of participants’ sexual orientation disclosure was built: the higher the index, the greater the disclosure. Factors associated with recent HIV testing (last test ≤ 1 year were identified using a multivariate logistic regression model adjusted for the CB-VCT programme of enrolment. Results. 716 MSM provided data on testing history. Overall, 49% were recently tested for HIV and 51% were not. Recently tested MSM had a higher homosexuality disclosure index (adjusted OR [95% confidence interval]: aOR = 1.2 [1.1–1.4], reported more inconsistent condom use during anal sex with men (aOR = 1.6 [1.2–2.1], and were less likely to have sex under the influence of club drugs (aOR = 0.6 [0.4–1.0]. Conclusion. New testing strategies should focus on those who live their homosexuality relatively secretly and those who use club drugs before sex. Governments should develop policies which encourage improved social acceptance of homosexuality as concealment of sexual orientation represents a major barrier to testing.

  7. Effects of harness transmitters on behavior and reproduction of wild mallards

    Science.gov (United States)

    Pietz, Pamela J.; Krapu, Gary L.; Greenwood, Raymond J.; Lokemoen, John T.

    1993-01-01

    Radio telemetry has been an important research tool in waterfowl studies for >20 years, yet little effort has been made to evaluate potential effects of transmitters on the birds that carry them. As part of a 4-year mallard (Anas platyrhynchos) study in the prairie pothole region of North Dakota and Minnesota, we compared radio-marked and unmarked female mallards in terms of percent time observed feeding, resting, and preening; nest initiation date; and clutch size and egg volume. Radio-marked females carried a 23-g back-mounted transmitter attached with a 2-loop harness (Dwyer 1972). On average, radio-marked females tended to feed less, rest and preen more, initiate nests later, and lay smaller clutches and eggs than unmarked females. Thus, behavioral and reproductive data from ducks marked with back-mounted harness-attached transmitters may be biased. We recommend that new designs of radio packages be field tested and caution that effects may be masked under extreme environmental conditions.

  8. Automated Functional Testing based on the Navigation of Web Applications

    Directory of Open Access Journals (Sweden)

    Boni García

    2011-08-01

    Full Text Available Web applications are becoming more and more complex. Testing such applications is an intricate hard and time-consuming activity. Therefore, testing is often poorly performed or skipped by practitioners. Test automation can help to avoid this situation. Hence, this paper presents a novel approach to perform automated software testing for web applications based on its navigation. On the one hand, web navigation is the process of traversing a web application using a browser. On the other hand, functional requirements are actions that an application must do. Therefore, the evaluation of the correct navigation of web applications results in the assessment of the specified functional requirements. The proposed method to perform the automation is done in four levels: test case generation, test data derivation, test case execution, and test case reporting. This method is driven by three kinds of inputs: i UML models; ii Selenium scripts; iii XML files. We have implemented our approach in an open-source testing framework named Automatic Testing Platform. The validation of this work has been carried out by means of a case study, in which the target is a real invoice management system developed using a model-driven approach.

  9. Score-based tests of measurement invariance: Use in practice

    Directory of Open Access Journals (Sweden)

    Ting eWang

    2014-05-01

    Full Text Available In this paper, we consider a family of recently-proposed measurement invariance tests that are based on the scores of a fitted model. This family can be used to test for measurement invariance w.r.t. a continuous auxiliary variable, without pre-specification of subgroups. Moreover, the family can be used when one wishes to test for measurement invariance w.r.t. an ordinal auxiliary variable, yielding test statistics that are sensitive to violations that are monotonically related to the ordinal variable (and less sensitive to non-monotonic violations. The paper is specifically aimed at potential users of the tests who may wish to know (i how the tests can be employed for their data, and (ii whether the tests can accurately identify specific models parameters that violate measurement invariance (possibly in the presence of model misspecification. After providing an overview of the tests, we illustrate their general use via the R packages lavaan and strucchange. We then describe two novel simulations that provide evidence of the tests' practical abilities. As a whole, the paper provides researchers with the tools and knowledge needed to apply these tests to general measurement invariance scenarios.

  10. When sparks fly harnessing the power of group creativity

    CERN Document Server

    Leonard, Dorothy

    2005-01-01

    Creativity and innovation are evergreen topics. Particularly in today's tough marketplace, companies in every industry are looking for ways to harness creativity and innovation to spur growth and enhance competitiveness. This book differs from many books on creativity in that its focus is on how to manage a group, rather than individual creativity. It refutes much conventional wisdom about where creativity comes from, particularly that creativity does not stem from the random genius of individuals. The authors reveal specific group configurations and strategies that can unleash the collective creativity of any team or group.

  11. "Hello, World!" Harnessing Social Media for the Rosetta Mission

    Science.gov (United States)

    Baldwin, E.; Mignone, C.; Scuka, D.; Homfeld, A. M.; Ranero, K.; Rolfe, E.; Bennett, M.; Schepers, A.; O'Flaherty, K. S.; Bauer, M.; McCaughrean, M.

    2016-03-01

    The European Space Agency's comet-chasing Rosetta mission was launched in 2004, before social media became a popular tool for mainstream communication. As it reached its destination ten years later, new audiences were reached and inspired by this once-in-a-lifetime event by harnessing a range of outlets for communicating the key messages. These included traditional online platforms, such as news websites, blogs, and Livestream, as well as Twitter, Facebook, Instagram, Flickr, YouTube, Google+ and SoundCloud. In this article, we outline the role social media channels played in making Rosetta one of the European Space Agency's biggest communication and public engagement successes.

  12. Harnessing natural product assembly lines: structure, promiscuity, and engineering.

    Science.gov (United States)

    Ladner, Christopher C; Williams, Gavin J

    2016-03-01

    Many therapeutically relevant natural products are biosynthesized by the action of giant mega-enzyme assembly lines. By leveraging the specificity, promiscuity, and modularity of assembly lines, a variety of strategies has been developed that enables the biosynthesis of modified natural products. This review briefly summarizes recent structural advances related to natural product assembly lines, discusses chemical approaches to probing assembly line structures in the absence of traditional biophysical data, and surveys efforts that harness the inherent or engineered promiscuity of assembly lines for the synthesis of non-natural polyketides and non-ribosomal peptide analogues.

  13. Development of Taiwan Smell Identification Test: a quick office-based smell screening test for Taiwanese.

    Science.gov (United States)

    Hsu, Ning-I; Lai, Jen-Tsung; Shen, Ping-Hung

    2015-01-01

    Objective smell tests not only identify levels of smelling ability but also provide information on changes in olfaction after treatment. Odor identification is strongly socially and culturally dependent; therefore, the odorants used in a smell identification test should be familiar to the test population. We developed this smell test for Taiwanese populations with two aims: the test odors should be familiar to Taiwanese and the test should be easily and quickly administered in a busy clinic. Additives that are familiar to Taiwanese people were selected for this smell identification test. Subsequently, the test was validated with the traditional Chinese version of the University of Pennsylvania Smell Identification Test (TC-UPSIT). Finally, this Taiwan Smell Identification Test (TWSIT) was implemented in daily clinical use, and cut-off points of "normosmia," "hyposmia," and "anosmia" were established. A total of 1000 subjects were included in the market survey to identify commonly recognized odors. Eight odorants with identification rate greater than 95% were selected. The TWSIT is an array of multiple-choice questions to select the odor. In addition, patient also reported the strength of the odor. The full score was 48. Thirty-seven patients simultaneously received both TWSIT and TC-UPSIT, and the correlation was high (r = 0.874). Based on the testing results of an additional 187 subjects, we concluded that scores of 47-48, 15-44, and 2-12 corresponded to normosmia, hyposmia, and anosmia, respectively. Patients with scores falling in the gaps require retesting at a later time. The TWSIT is a quick, office-based, and useful odor identification tool for Taiwanese. The experience of developing a culturally specific olfaction test like the TWSIT can be applied in different countries and cultures.

  14. Academic integrity "captured" by a personality-based test

    Directory of Open Access Journals (Sweden)

    Okanović Predrag

    2013-01-01

    Full Text Available The main goal of this study was to develop and validate a personality-based academic integrity test which could serve as a predictor of students’ academic dishonesty. A new Academic Integrity Test (AIT, based on methodological principles accepted in the field of work integrity, was created during this study. The test was developed on one student sample (N=350, and then validated on another (N=471. Validation of the AIT confirmed its relations with three dimensions previously found to be consistent correlates of work integrity measures - Conscientiousness, Aggressiveness and Neuroticism, with the addition of Negative Valence. The correlation between the AIT and a cognitive ability measure was not significant, which is in accordance with previous research. The test retained significant relations with the aforementioned personality measures in simulated applicant condition (except with Neuroticism, leading to the conclusion that the AIT maintains construct validity in situations susceptible to self-presentation.

  15. A Model Based Security Testing Method for Protocol Implementation

    Directory of Open Access Journals (Sweden)

    Yu Long Fu

    2014-01-01

    Full Text Available The security of protocol implementation is important and hard to be verified. Since the penetration testing is usually based on the experience of the security tester and the specific protocol specifications, a formal and automatic verification method is always required. In this paper, we propose an extended model of IOLTS to describe the legal roles and intruders of security protocol implementations, and then combine them together to generate the suitable test cases to verify the security of protocol implementation.

  16. Small scale motor tests of ADN/GAP based propellants

    OpenAIRE

    Gettwert, Volker; Fischer, Sebastian

    2015-01-01

    Different ADN/GAP based propellants were evaluated as a potential replacement of the smoky AP based composite propellant and low signature double base propellants. The paper focuses on burning tests of propellants in a combustion chamber. The experimental results of an ADN/GAP, ADN/FOX12/GAP and Al/ADN/GAP propellant were compared with a standard Al/AP/HTPB propellant. In all cases the obtained experimental gravimetric specific impulse of the ADN/GAP based propellants were higher compared to ...

  17. Path-oriented test cases generation based adaptive genetic algorithm.

    Science.gov (United States)

    Bao, Xiaoan; Xiong, Zijian; Zhang, Na; Qian, Junyan; Wu, Biao; Zhang, Wei

    2017-01-01

    The automatic generation of test cases oriented paths in an effective manner is a challenging problem for structural testing of software. The use of search-based optimization methods, such as genetic algorithms (GAs), has been proposed to handle this problem. This paper proposes an improved adaptive genetic algorithm (IAGA) for test cases generation by maintaining population diversity. It uses adaptive crossover rate and mutation rate in dynamic adjustment according to the differences between individual similarity and fitness values, which enhances the exploitation of searching global optimum. This novel approach is experimented and tested on a benchmark and six industrial programs. The experimental results confirm that the proposed method is efficient in generating test cases for path coverage.

  18. Asymptotic formulae for likelihood-based tests of new physics

    Science.gov (United States)

    Cowan, Glen; Cranmer, Kyle; Gross, Eilam; Vitells, Ofer

    2011-02-01

    We describe likelihood-based statistical tests for use in high energy physics for the discovery of new phenomena and for construction of confidence intervals on model parameters. We focus on the properties of the test procedures that allow one to account for systematic uncertainties. Explicit formulae for the asymptotic distributions of test statistics are derived using results of Wilks and Wald. We motivate and justify the use of a representative data set, called the "Asimov data set", which provides a simple method to obtain the median experimental sensitivity of a search or measurement as well as fluctuations about this expectation.

  19. Asymptotic formulae for likelihood-based tests of new physics

    Energy Technology Data Exchange (ETDEWEB)

    Cowan, Glen [Royal Holloway, University of London, Physics Department, Egham (United Kingdom); Cranmer, Kyle [New York University, Physics Department, New York, NY (United States); Gross, Eilam; Vitells, Ofer [Weizmann Institute of Science, Rehovot (Israel)

    2011-02-15

    We describe likelihood-based statistical tests for use in high energy physics for the discovery of new phenomena and for construction of confidence intervals on model parameters. We focus on the properties of the test procedures that allow one to account for systematic uncertainties. Explicit formulae for the asymptotic distributions of test statistics are derived using results of Wilks and Wald. We motivate and justify the use of a representative data set, called the ''Asimov data set'', which provides a simple method to obtain the median experimental sensitivity of a search or measurement as well as fluctuations about this expectation. (orig.)

  20. Using computer-based tests for information science

    Directory of Open Access Journals (Sweden)

    David Callear

    1997-12-01

    Full Text Available The introduction of objective testing using computer software does not necessarily represent innovative assessment. Where tests occur as an add-on to a course, are timeconstrained, closed-book, invigilated, and where there is little (or no feedback of results to the students, such testing is best regarded as an innovative technique for traditional summative assessment. A computer-based examination of this nature using the commercial software Question Mark has been operating for a number of years in the Department of Information Science at Portsmouth, in the second-year unit for Logic Programming, with student numbers up to 160.

  1. Diagnosis of Food Allergy Based on Oral Food Challenge Test

    Directory of Open Access Journals (Sweden)

    Komei Ito

    2009-01-01

    Full Text Available Diagnosis of food allergy should be based on the observation of allergic symptoms after intake of the suspected food. The oral food challenge test (OFC is the most reliable clinical procedure for diagnosing food allergy. The OFC is also applied for the diagnosis of tolerance of food allergy. The Japanese Society of Pediatric Allergy and Clinical Immunology issued the 'Japanese Pediatric Guideline for Oral Food Challenge Test in Food Allergy 2009' in April 2009, to provide information on a safe and standardized method for administering the OFC. This review focuses on the clinical applications and procedure for the OFC, based on the Japanese OFC guideline.

  2. Diagnosis of food allergy based on oral food challenge test.

    Science.gov (United States)

    Ito, Komei; Urisu, Atsuo

    2009-12-01

    Diagnosis of food allergy should be based on the observation of allergic symptoms after intake of the suspected food. The oral food challenge test (OFC) is the most reliable clinical procedure for diagnosing food allergy. The OFC is also applied for the diagnosis of tolerance of food allergy. The Japanese Society of Pediatric Allergy and Clinical Immunology issued the 'Japanese Pediatric Guideline for Oral Food Challenge Test in Food Allergy 2009' in April 2009, to provide information on a safe and standardized method for administering the OFC. This review focuses on the clinical applications and procedure for the OFC, based on the Japanese OFC guideline.

  3. Design of Test Wrapper Scan Chain Based on Differential Evolution

    Directory of Open Access Journals (Sweden)

    Aijun Zhu

    2013-08-01

    Full Text Available Integrated Circuit has entered the era of design of the IP-based SoC (System on Chip, which makes the IP core reuse become a key issue. SoC test wrapper design for scan chain is a NP Hard problem, we propose an algorithm based on Differential Evolution (DE to design wrapper scan chain. Through group’s mutation, crossover and selection operations, the design of test wrapper scan chain is achieved. Experimental verification is carried out according to the international standard benchmark ITC’02. The results show that the algorithm can obtain shorter longest wrapper scan chains, compared with other algorithms.

  4. Validation of the colorado psychiatry evidence-based medicine test.

    Science.gov (United States)

    Rothberg, Brian; Feinstein, Robert E; Guiton, Gretchen

    2013-09-01

    Evidence-based medicine (EBM) has become an important part of residency education, yet many EBM curricula lack a valid and standardized tool to identify learners' prior knowledge and assess progress. We developed an EBM examination in psychiatry to measure our effectiveness in teaching comprehensive EBM to residents. We developed a psychiatry EBM test using the validated EBM Fresno Test of Competence for family medicine. The test consists of case scenarios with open-ended questions. We also developed a scoring rubric and obtained reliability with multiple raters. Fifty-seven residents provided test data after completing 3, 6, 25, or 31 EBM sessions. The number of sessions for each resident was based on their length of training in our program. The examination had strong interrater reliability, internal reliability, and item discrimination. Many residents showed significant improvement on their examination scores when data were compared from tests taken before and after a sequence of teaching sessions. Also, a threshold for the level of expert on the examination was established using test data from 5 EBM teacher-experts. We successfully developed a valid and reliable EBM examination for use with psychiatry residents to measure essential EBM skills as part of a larger project to encourage EBM practice for residents in routine patient care. The test provides information on residents' knowledge in EBM from entry level concepts through expert performance. It can be used to place incoming residents in appropriate levels of an EBM curriculum and to monitor the effectiveness of EBM instruction.

  5. Designing for learner engagement with computer-based testing

    Directory of Open Access Journals (Sweden)

    Richard Walker

    2016-12-01

    Full Text Available The issues influencing student engagement with high-stakes computer-based exams were investigated, drawing on feedback from two cohorts of international MA Education students encountering this assessment method for the first time. Qualitative data from surveys and focus groups on the students’ examination experience were analysed, leading to the identification of engagement issues in the delivery of high-stakes computer-based assessments.The exam combined short-answer open-response questions with multiple-choice-style items to assess knowledge and understanding of research methods. The findings suggest that engagement with computer-based testing depends, to a lesser extent, on students’ general levels of digital literacy and, to a greater extent, on their information technology (IT proficiency for assessment and their ability to adapt their test-taking strategies, including organisational and cognitive strategies, to the online assessment environment. The socialisation and preparation of students for computer-based testing therefore emerge as key responsibilities for instructors to address, with students requesting increased opportunities for practice and training to develop the IT skills and test-taking strategies necessary to succeed in computer-based examinations. These findings and their implications in terms of instructional responsibilities form the basis of a proposal for a framework for Learner Engagement with e-Assessment Practices.

  6. Sequential probability ratio tests based on grouped observations

    OpenAIRE

    Eger, Karl-Heinz; Tsoy, Evgeni Borisovich

    2010-01-01

    This paper deals with sequential likelihood ratio tests based on grouped observations. It is demonstrated that the method of conjugated parameter pairs known from the non-grouped case can be extended to the grouped case obtaining Waldlike approximations for the OC- and ASN- function. For near hypotheses so-called F-optimal groupings are recommended. As example an SPRT based on grouped observations for the parameter of an exponentially distributed random var...

  7. Pharmacists performing quality spirometry testing: an evidence based review.

    Science.gov (United States)

    Cawley, Michael J; Warning, William J

    2015-10-01

    The scope of pharmacist services for patients with pulmonary disease has primarily focused on drug related outcomes; however pharmacists have the ability to broaden the scope of clinical services by performing diagnostic testing including quality spirometry testing. Studies have demonstrated that pharmacists can perform quality spirometry testing based upon international guidelines. The primary aim of this review was to assess the published evidence of pharmacists performing quality spirometry testing based upon American Thoracic Society/European Respiratory Society (ATS/ERS) guidelines. In order to accomplish this, the description of evidence and type of outcome from these services were reviewed. A literature search was conducted using five databases [PubMed (1946-January 2015), International Pharmaceutical Abstracts (1970 to January 2015), Cumulative Index of Nursing and Allied Health Literature, Cochrane Central Register of Controlled Trials and Cochrane Database of Systematic Reviews] with search terms including pharmacy, spirometry, pulmonary function, asthma or COPD was conducted. Searches were limited to publications in English and reported in humans. In addition, Uniform Resource Locators and Google Scholar searches were implemented to include any additional supplemental information. Eight studies (six prospective multi-center trials, two retrospective single center studies) were included. Pharmacists in all studies received specialized training in performing spirometry testing. Of the eight studies meeting inclusion and exclusion criteria, 8 (100%) demonstrated acceptable repeatability of spirometry testing based upon standards set by the ATS/ERS guidelines. Acceptable repeatability of seven studies ranged from 70 to 99% consistent with published data. Available evidence suggests that quality spirometry testing can be performed by pharmacists. More prospective studies are needed to add to the current evidence of quality spirometry testing performed by

  8. A generalized association test based on U statistics.

    Science.gov (United States)

    Wei, Changshuai; Lu, Qing

    2017-07-01

    Second generation sequencing technologies are being increasingly used for genetic association studies, where the main research interest is to identify sets of genetic variants that contribute to various phenotypes. The phenotype can be univariate disease status, multivariate responses and even high-dimensional outcomes. Considering the genotype and phenotype as two complex objects, this also poses a general statistical problem of testing association between complex objects. We here proposed a similarity-based test, generalized similarity U (GSU), that can test the association between complex objects. We first studied the theoretical properties of the test in a general setting and then focused on the application of the test to sequencing association studies. Based on theoretical analysis, we proposed to use Laplacian Kernel-based similarity for GSU to boost power and enhance robustness. Through simulation, we found that GSU did have advantages over existing methods in terms of power and robustness. We further performed a whole genome sequencing (WGS) scan for Alzherimer's disease neuroimaging initiative data, identifying three genes, APOE , APOC1 and TOMM40 , associated with imaging phenotype. We developed a C ++ package for analysis of WGS data using GSU. The source codes can be downloaded at https://github.com/changshuaiwei/gsu . weichangshuai@gmail.com ; qlu@epi.msu.edu. Supplementary data are available at Bioinformatics online.

  9. High Frequency Vibration Based Fatigue Testing of Developmental Alloys

    Science.gov (United States)

    Holycross, Casey M.; Srinivasan, Raghavan; George, Tommy J.; Tamirisakandala, Seshacharyulu; Russ, Stephan M.

    Many fatigue test methods have been previously developed to rapidly evaluate fatigue behavior. This increased test speed can come at some expense, since these methods may require non-standard specimen geometry or increased facility and equipment capability. One such method, developed by George et al, involves a base-excited plate specimen driven into a high frequency bending resonant mode. This resonant mode is of sufficient frequency (typically 1200 to 1700 Hertz) to accumulate 107 cycles in a few hours. One of the main limitations of this test method is that fatigue cracking is almost certainly guaranteed to be surface initiated at regions of high stress. This brings into question the validity of the fatigue test results, as compared to more traditional uniaxial, smooth-bar testing, since high stresses are subjecting only a small volume to fatigue damage. This limitation also brings into question the suitability of this method to screen developmental alloys, should their initiation life be governed by subsurface flaws. However, if applicable, the rapid generation of fatigue data using this method would facilitate faster design iterations, identifying more quickly, material and manufacturing process deficiencies. The developmental alloy used in this study was a powder metallurgy boron-modified Ti-6Al-4V, a new alloy currently being considered for gas turbine engine fan blades. Plate specimens were subjected to fully reversed bending fatigue. Results are compared with existing data from commercially available Ti-6Al-4V using both vibration based and more traditional fatigue test methods.

  10. Introduction to Permutation and Resampling-Based Hypothesis Tests

    Science.gov (United States)

    LaFleur, Bonnie J.; Greevy, Robert A.

    2009-01-01

    A resampling-based method of inference--permutation tests--is often used when distributional assumptions are questionable or unmet. Not only are these methods useful for obvious departures from parametric assumptions (e.g., normality) and small sample sizes, but they are also more robust than their parametric counterparts in the presences of…

  11. A valuation-Based Test of Market Timing

    NARCIS (Netherlands)

    Koeter-Kant, J.; Elliott, W.B.; Warr, R.S.

    2007-01-01

    We implement an earnings-based fundamental valuation model to test the impact of market timing on the firm's method of funding the financing deficit. We argue that our valuation metric provides a superior measure of equity misvaluation because it avoids multiple interpretation problems faced by the

  12. A sequential hypothesis test based on a generalized Azuma inequality

    NARCIS (Netherlands)

    Reijsbergen, D.P.; Scheinhardt, Willem R.W.; de Boer, Pieter-Tjerk

    We present a new power-one sequential hypothesis test based on a bound for the probability that a bounded zero-mean martingale ever crosses a curve of the form $a(n+k)^b$. The proof of the bound is of independent interest.

  13. Applications of decision theory to test-based decision making

    NARCIS (Netherlands)

    van der Linden, Willem J.

    1987-01-01

    The use of Bayesian decision theory to solve problems in test-based decision making is discussed. Four basic decision problems are distinguished: (1) selection; (2) mastery; (3) placement; and (4) classification, the situation where each treatment has its own criterion. Each type of decision can be

  14. Evaluating Computer-Based Test Accommodations for English Learners

    Science.gov (United States)

    Roohr, Katrina Crotts; Sireci, Stephen G.

    2017-01-01

    Test accommodations for English learners (ELs) are intended to reduce the language barrier and level the playing field, allowing ELs to better demonstrate their true proficiencies. Computer-based accommodations for ELs show promising results for leveling that field while also providing us with additional data to more closely investigate the…

  15. JTorX: Exploring Model-Based Testing

    NARCIS (Netherlands)

    Belinfante, Axel

    2014-01-01

    The overall goal of the work described in this thesis is: ``To design a flexible tool for state-of-the-art model-based derivation and automatic application of black-box tests for reactive systems, usable both for education and outside an academic context.'' From this goal, we derive functional and

  16. A Rasch-Based Validation of the Vocabulary Size Test

    Science.gov (United States)

    Beglar, David

    2010-01-01

    The primary purpose of this study was to provide preliminary validity evidence for a 140-item form of the Vocabulary Size Test, which is designed to measure written receptive knowledge of the first 14,000 words of English. Nineteen native speakers of English and 178 native speakers of Japanese participated in the study. Analyses based on the Rasch…

  17. Heart rate-based lactate minimum test: a reproducible method.

    NARCIS (Netherlands)

    Strupler, M.; Muller, G.; Perret, C.

    2009-01-01

    OBJECTIVE: To find the individual intensity for aerobic endurance training, the lactate minimum test (LMT) seems to be a promising method. LMTs described in the literature consist of speed or work rate-based protocols, but for training prescription in daily practice mostly heart rate is used. The

  18. Laboratory test of an APS-based sun sensor prototype

    Science.gov (United States)

    Rufino, Giancarlo; Perrotta, Alessandro; Grassi, Michele

    2017-11-01

    This paper deals with design and prototype development of an Active Pixel Sensor - based miniature sun sensor and a laboratory facility for its indoor test and calibration. The miniature sun sensor is described and the laboratory test facility is presented in detail. The major focus of the paper is on tests and calibration of the sensor. Two different calibration functions have been adopted. They are based, respectively, on a geometrical model, which has required least-squares optimisation of system physical parameters estimates, and on neural networks. Calibration results are presented for the above solutions, showing that accuracy in the order of 0.01° has been achieved. Neural calibration functions have attained better performance thanks to their intrinsic auto-adaptive structure.

  19. Computer Based Test Untuk Seleksi Masuk Politeknik Negeri Bengkalis

    Directory of Open Access Journals (Sweden)

    Agus Tedyyana

    2017-11-01

    Full Text Available AbstrakPenyeleksian calon mahasiswa baru dapat dilakukan dengan aplikasi Computer Based Test (CBT. Metode yang digunakan meliputi teknik pengumpulan data, analisis sistem, model perancangan, implementasi dan pengujian. Penelitian ini menghasilkan aplikasi CBT dimana soal yang dimunculkan dari bank soal melalui proses pengacakan dengan tidak akan memunculkan soal yang sama dengan menggunakan metoda Fisher-Yates Shuffle. Dalam proses pengamanan informasi soal saat terhubung ke jaringan maka diperlukan teknik untuk penyandian pesan agar soal tersebut sebeum dimunculkan melewati proses enkripsi dan deskripsi data terlebih dahulu maka digunakan algoritma kriptografi  RSA. Metode perancangan perangkat lunak menggunakan model waterfall, perancangan database menggunakan entity relationship diagram, perancangan antarmuka menggunakan hypertext markup language (HTML Cascading Style Sheet (CSS dan jQuery serta diimplementasikan berbasis web dengan menggunakan bahasa pemrograman PHP dan database MySQL, Arsitektur jaringan yang digunakan aplikasi Computer Based Test adalah model jaringan client-server dengan jaringan Local Area Network (LAN. Kata kunci: Computer Based Test, Fisher-Yates Shuffle, Criptography, Local Area Network AbstractSelection of new student candidates can be done with Computer Based Test (CBT application. The methods used include data collection techniques, system analysis, design model, implementation and testing. This study produces a CBT application where the questions raised from the question bank through randomization process will not bring up the same problem using the Fisher-Yates Shuffle method. In the process of securing information about the problem when connected to the network it is necessary techniques for encoding the message so that the problem before appear through the process of encryption and description of data first then used RSA cryptography algorithm. Software design method using waterfall model, database design

  20. Development of a new test method for Mineral Based Composites

    DEFF Research Database (Denmark)

    Täljsten, Björn; Orosz, Katalin

    2008-01-01

    The well-known wedge splitting test, often used for characterizing brittle materials has been modified and adapted to testing MBC-reinforced concrete under splitting load. MBC (Mineral Based Composites) is a newly developed strengthening system for existing concrete structures where FRPs, mainly...... CFRP grids are externally bonded to the concrete surface by means of cementitious bonding agents. Crack development, crack patterns, crack opening displacement (COD) versus splitting load and fracture energy are investigated and evaluated. Development of a suitable test specimen and test setup has been...... accomplished. Bond provided by both mortars was excellent leading to CFRP rupture. By applying PVA-reinforced ductile ECC as bonding agent, improved performance, significantly higher fracture energy, multiple cracking and enhanced ductility were observed, caused by improved bond between grid and mortar due...

  1. Examining the Use of Web-Based Tests for Testing Academic Vocabulary in EAP Instruction

    Science.gov (United States)

    Dashtestani, Reza

    2015-01-01

    Interest in Web-based and computer-assisted language testing is growing in the field of English for academic purposes (EAP). In this study, four groups of undergraduate EAP students (n = 120), each group consisted of 30 students, were randomly selected from four different disciplines, i.e. biology, political sciences, psychology, and law. The four…

  2. Failing Tests: Commentary on "Adapting Educational Measurement to the Demands of Test-Based Accountability"

    Science.gov (United States)

    Thissen, David

    2015-01-01

    In "Adapting Educational Measurement to the Demands of Test-Based Accountability" Koretz takes the time-honored engineering approach to educational measurement, identifying specific problems with current practice and proposing minimal modifications of the system to alleviate those problems. In response to that article, David Thissen…

  3. A novel PMT test system based on waveform sampling

    Science.gov (United States)

    Yin, S.; Ma, L.; Ning, Z.; Qian, S.; Wang, Y.; Jiang, X.; Wang, Z.; Yu, B.; Gao, F.; Zhu, Y.; Wang, Z.

    2018-01-01

    Comparing with the traditional test system based on a QDC and TDC and scaler, a test system based on waveform sampling is constructed for signal sampling of the 8"R5912 and the 20"R12860 Hamamatsu PMT in different energy states from single to multiple photoelectrons. In order to achieve high throughput and to reduce the dead time in data processing, the data acquisition software based on LabVIEW is developed and runs with a parallel mechanism. The analysis algorithm is realized in LabVIEW and the spectra of charge, amplitude, signal width and rising time are analyzed offline. The results from Charge-to-Digital Converter, Time-to-Digital Converter and waveform sampling are discussed in detailed comparison.

  4. Psychometric properties of a test in evidence based practice: the Spanish version of the Fresno test

    Directory of Open Access Journals (Sweden)

    Jiménez-Villa Josep

    2010-06-01

    Full Text Available Abstract Background Validated instruments are needed to evaluate the programmatic impact of Evidence Based Practice (EBP training and to document the competence of individual trainees. This study aimed to translate the Fresno test into Spanish and subsequently validate it, in order to ensure the equivalence of the Spanish version against the original English version. Methods Before and after study performed between October 2007 and June 2008. Three groups of participants: (a Mentors of family medicine residents (expert group (n = 56; (b Family medicine physicians (intermediate experience group (n = 17; (c Family medicine residents (novice group (n = 202; Medical residents attended an EBP course, and two sets of the test were administered before and after the course. The Fresno test is a performance based measure for use in medical education that assesses EBP skills. The outcome measures were: inter-rater and intra-rater reliability, internal consistency, item analyses, construct validity, feasibility of administration, and responsiveness. Results Inter-rater correlations were 0.95 and 0.85 in the pre-test and the post-test respectively. The overall intra-rater reliability was 0.71 and 0.81 in the pre-test and post-test questionnaire, respectively. Cronbach's alpha was 0.88 and 0.77, respectively. 152 residents (75.2% returned both sets of the questionnaire. The observed effect size for the residents was 1.77 (CI 95%: 1.57-1.95, the standardised response mean was 1.65 (CI 95%:1.47-1.82. Conclusions The Spanish version of the Fresno test is a useful tool in assessing the knowledge and skills of EBP in Spanish-speaking residents of Family Medicine.

  5. Lateral flow-based antibody testing for Chlamydia trachomatis.

    Science.gov (United States)

    Gwyn, Sarah; Mitchell, Alexandria; Dean, Deborah; Mkocha, Harran; Handali, Sukwan; Martin, Diana L

    2016-08-01

    We describe here a lateral flow-based assay (LFA) for the detection of antibodies against immunodominant antigen Pgp3 from Chlamydia trachomatis, the causative agent of urogenital chlamydia infection and ocular trachoma. Optimal signal detection was achieved when the gold-conjugate and test line contained Pgp3, creating a dual sandwich capture assay. The LFA yielded positive signals with serum and whole blood but not with eluted dried blood spots. For serum, the agreement of the LFA with the non-reference multiplex assay was 96%, the specificity using nonendemic pediatric sera was 100%, and the inter-rater agreement was κ=0.961. For whole blood, the agreement of LFA with multiplex was 81.5%, the specificity was 100%, and the inter-rater agreement was κ=0.940. The LFA was tested in a field environment and yielded similar results to those from laboratory-based testing. These data show the successful development of a lateral flow assay for detection of antibodies against Pgp3 with reliable use in field settings, which would make antibody-based testing for trachoma surveillance highly practical, especially after cessation of trachoma elimination programs. Published by Elsevier B.V.

  6. Online vibration-based crack detection during fatigue testing

    Energy Technology Data Exchange (ETDEWEB)

    Peeters, B.; Vecchio, A.; Auweraer, H. van der [LMS International, Heverlee (Belgium); Mevel, L. [INRIA, Rennes (France); Vanlanduit, S.; Guillaume, P. [Dept. of Mechanical Engineering, VUB, Brussels (Belgium); Goursat, M. [Rocquencourt, INRIA, Le Chesnay (France)

    2003-07-01

    When performing fatigue tests, it is essential to monitor the degradation of the structure with an increasing number of fatigue cycles. In this article, a vibration-based damage detection method will be proposed. Such a method has the advantage that it operates online with the fatigue test. Especially for structures with very high fatigue strength, it is important that the test does not have to be interrupted. The damage detection method that will be used is based on a residual generated from a stochastic subspace identification method. The basic idea is that a model for the undamaged structure is identified and that, afterwards, vibration measurements from a possibly damaged structure are confronted with this model. A statistical local approach hypothesis testing is used to assess the deviation of the new data from the nominal model. After introducing the damage detection method, its performance will be illustrated on data from a fatigue experiment. The method will be compared to other linear and non-linear vibration-based damage detection methods. (orig.)

  7. TR-EDB: Test Reactor Embrittlement Data Base, Version 1

    Energy Technology Data Exchange (ETDEWEB)

    Stallmann, F.W.; Wang, J.A.; Kam, F.B.K. [Oak Ridge National Lab., TN (United States)

    1994-01-01

    The Test Reactor Embrittlement Data Base (TR-EDB) is a collection of results from irradiation in materials test reactors. It complements the Power Reactor Embrittlement Data Base (PR-EDB), whose data are restricted to the results from the analysis of surveillance capsules in commercial power reactors. The rationale behind their restriction was the assumption that the results of test reactor experiments may not be applicable to power reactors and could, therefore, be challenged if such data were included. For this very reason the embrittlement predictions in the Reg. Guide 1.99, Rev. 2, were based exclusively on power reactor data. However, test reactor experiments are able to cover a much wider range of materials and irradiation conditions that are needed to explore more fully a variety of models for the prediction of irradiation embrittlement. These data are also needed for the study of effects of annealing for life extension of reactor pressure vessels that are difficult to obtain from surveillance capsule results.

  8. Titan TTCN-3 Based Test Framework for Resource Constrained Systems

    Directory of Open Access Journals (Sweden)

    Yushev Artem

    2016-01-01

    Full Text Available Wireless communication systems more and more become part of our daily live. Especially with the Internet of Things (IoT the overall connectivity increases rapidly since everyday objects become part of the global network. For this purpose several new wireless protocols have arisen, whereas 6LoWPAN (IPv6 over Low power Wireless Personal Area Networks can be seen as one of the most important protocols within this sector. Originally designed on top of the IEEE802.15.4 standard it is a subject to various adaptions that will allow to use 6LoWPAN over different technologies; e.g. DECT Ultra Low Energy (ULE. Although this high connectivity offers a lot of new possibilities, there are several requirements and pitfalls coming along with such new systems. With an increasing number of connected devices the interoperability between different providers is one of the biggest challenges, which makes it necessary to verify the functionality and stability of the devices and the network. Therefore testing becomes one of the key components that decides on success or failure of such a system. Although there are several protocol implementations commonly available; e.g., for IoT based systems, there is still a lack of according tools and environments as well as for functional and conformance testing. This article describes the architecture and functioning of the proposed test framework based on Testing and Test Control Notation Version 3 (TTCN-3 for 6LoWPAN over ULE networks.

  9. Model-based automated testing of critical PLC programs.

    CERN Document Server

    Fernández Adiego, B; Tournier, J-C; González Suárez, V M; Bliudze, S

    2014-01-01

    Testing of critical PLC (Programmable Logic Controller) programs remains a challenging task for control system engineers as it can rarely be automated. This paper proposes a model based approach which uses the BIP (Behavior, Interactions and Priorities) framework to perform automated testing of PLC programs developed with the UNICOS (UNified Industrial COntrol System) framework. This paper defines the translation procedure and rules from UNICOS to BIP which can be fully automated in order to hide the complexity of the underlying model from the control engineers. The approach is illustrated and validated through the study of a water treatment process.

  10. A comparison of laboratory-based kayak testing protocols.

    Science.gov (United States)

    Jones, Maddison J; Peeling, Peter

    2014-03-01

    To compare the differences in peak oxygen uptake (VO2peak) and lactate threshold (LT2) between the 7 × 4-min incremental step test (7-ST) and the maximal accumulated oxygen deficit (MAOD) test protocols in sprint kayak athletes. Nine highly trained kayak athletes performed the 2 laboratory test protocols. The 7-ST involved six 4-min submaximal incremental stages, each separated by a 1-min recovery, before a 4-min all-out effort. The MAOD test involved four 4-min submaximal incremental stages (also with each stage separated by a 1-min recovery), followed by 20-min recovery and a 4-min all-out effort. No statistically significant differences in VO2peak were recorded between the 2 protocols (P > .05). However, distance covered, power output, stroke rate, and speed were almost certainly greater in the MAOD test (magnitude-based inference: 99-100% positive), while blood lactate (BLa), heart rate (HR), and rating of perceived exertion (RPE) were likely lower (magnitude-based inference: 78-92% negative). The derived measures of LT2 (excluding HR) were not different between the 2 protocols. The results of this study suggest that both the 7-ST and MAOD test protocols are comparable with regard to the measurement of VO2peak and LT2 in highly trained sprint kayak athletes. However, since differences in the measures of distance traveled, power, stroke rate, HR, BLa, and RPE were reported in the maximal stage of the these 2 test protocols, their interchangeable use in a laboratory setting is not ideal if the data output is to be compared and contrasted over time.

  11. Automated Model-Based Testing of Role-Based Access Control Using Predicate/Transition Nets

    OpenAIRE

    Xu, Dianxiang; Kent, Michael; Thomas, Lijo; Mouelhi, Tejeddine; Le Traon, Yves

    2015-01-01

    Role-based access control is an important access control method for securing computer systems. A role-based access control policy can be implemented incorrectly due to various reasons, such as programming errors. Defects in the implementation may lead to unauthorized access and security breaches. To reveal access control defects, this paper presents a model-based approach to automated generation of executable access control tests using predicate/transition nets. Role-permission test models ar...

  12. Harnessing plant-microbe interactions for enhancing farm productivity.

    Science.gov (United States)

    Macdonald, Catriona; Singh, Brajesh

    2014-01-01

    Declining soil fertility and farm productivity is a major global concern in order to achieve food security for a burgeoning world population. It is reported that improving soil health alone can increase productivity by 10-15% and in combination with efficient plant traits, farm productivity can be increased up to 50-60%. In this article we explore the emerging microbial and bioengineering technologies, which can be employed to achieve the transformational increase in farm productivity and can simultaneously enhance environmental outcomes i.e., low green house gas (GHG) emissions. We argue that metagenomics, meta-transcriptomics and metabolomics have potential to provide fundamental knowledge on plant-microbes interactions necessary for new innovations to increase farm productivity. Further, these approaches provide tools to identify and select novel microbial/gene resources which can be harnessed in transgenic and designer plant technologies for enhanced resource use efficiencies.

  13. Bispecific antibodies and CARs: generalized immunotherapeutics harnessing T cell redirection.

    Science.gov (United States)

    Zhukovsky, Eugene A; Morse, Richard J; Maus, Marcela V

    2016-06-01

    To realize the full potential of cancer immunotherapy, the latest generation immunotherapeutics are designed to harness the potent tumor-killing capacity of T cells. Thus, to mobilize T cells, new optimized bispecific antibody (BsAb) designs, enabling efficient polyclonal redirection of cytotoxic activity through binding to CD3 and a Tumor Associated Antigen (TAA) and refined genetically modified T cells have recently expanded the arsenal of available options for cancer treatment. This review presents the current understanding of the parameters crucial to the design of optimal T cell redirecting BsAb and chimeric antigen receptor (CAR)-modified T cells. However, there are additional questions that require thorough elucidation. Both modalities will benefit from design changes that may increase the therapeutic window. One such approach could employ the discrimination afforded by multiple TAA to significantly increase selectivity. Copyright © 2016 Elsevier Ltd. All rights reserved.

  14. Spil har potentiale som motivation for læring

    DEFF Research Database (Denmark)

    Hedegaard, Lars Norup

    2016-01-01

    En designbaseret empirisk undersøgelse af almindeligt anvendte gamification elementer. Gamification har til formål at skabe fornøjelse, samt en følelse af leg, i ikke-spil miljøer. Grundet en øget brug af gamification på arbejdspladser og i læreprocesser ses området vigtigt at undersøge yderligere....... Projektet søger at belyse, hvordan gamification påvirker motivationen for læring, herunder hvordan almindeligt anvendte spil-elementer og -genrer kan indgå i planlægningen af læringsaktiviteter. Projektet tager omdrejningspunkt i de studerendes oplevede erfaringer, med den antagelse, at intervention i...

  15. Pattern of injury after rock-climbing falls is not determined by harness type.

    Science.gov (United States)

    Hohlrieder, Matthias; Lutz, Martin; Schubert, Heinrich; Eschertzhuber, Stephan; Mair, Peter

    2007-01-01

    Experimental data indicate that when using a sit harness alone, any major fall during rock climbing may cause life-threatening thoraco-lumbar hyperextension trauma or "head down position" during suspension. To clarify the actual influence of the type of harness on the pattern and severity of injury, accidents involving a major fall in a climbing harness were analyzed retrospectively. Individuals with a height of fall equal to or exceeding 5 m were identified through a search of accident and emergency records for the period from 2000 to 2004. Data concerning the circumstances of the fall and the patterns of injury were obtained from personal interviews, flight and accident reports, as well as hospital medical records. Of a total of 113 climbers identified, 73 (64.6%) used a sit harness alone, whereas 40 (35.4%) used a body harness. Fractures and dislocations of the extremities, the shoulder, and the pelvic region were the most common injuries, while the most severe injuries occurred in the head and neck region. Although most falls were associated with mild or moderate injuries, 13 (11.5%) climbers sustained severe or critical multisystem trauma. Falls on more difficult routes were associated with less severe injury. The type of harness used did not influence the pattern or severity of injury. In particular, no evidence was found for the existence of a thoraco-lumbar hyperextension trauma. The type of harness does not influence the pattern or severity of injury, and the forces transferred via the harness do not cause a specific harness-induced pathology. We did not find any evidence that hyperextension trauma of the thoraco-lumbar region is an important mechanism of injury in climbers using a sit harness alone. Rock contact during the fall, and not the force transferred through the harness, is the major cause of significant injury in climbing accidents.

  16. Genetic mapping of rust resistance genes in confection sunflower line HA-R6 and oilseed line RHA 397.

    Science.gov (United States)

    Gong, L; Gulya, T J; Markell, S G; Hulke, B S; Qi, L L

    2013-08-01

    Few widely effective resistance sources to sunflower rust, incited by Puccinia helianthi Schwein., have been identified in confection sunflower (Helianthus annuus L.). The USDA inbred line HA-R6 is one of the few confection sunflower lines resistant to rust. A previous allelism test indicated that rust resistance genes in HA-R6 and RHA 397, an oilseed-type restorer line, are either allelic or closely linked; however, neither have been characterized nor molecularly mapped. The objectives of this study are (1) to locate the rust resistance genes in HA-R6 and RHA 397 on a molecular map, (2) to develop closely linked molecular markers for rust resistance diagnostics, and (3) to determine the resistance spectrum of two lines when compared with other rust-resistant lines. Two populations of 140 F2:3 families each from the crosses of HA 89, as susceptible parent, with HA-R6 and RHA 397 were inoculated with race 336 of P. helianthi in the greenhouse. The resistance genes (R-genes) in HA-R6 and RHA 397 were molecularly mapped to the lower end of linkage group 13, which encompasses a large R-gene cluster, and were designated as R 13a and R 13b, respectively. In the initial maps, SSR (simple sequence repeat) and InDel (insertion and deletion) markers revealed 2.8 and 8.2 cM flanking regions for R 13a and R 13b, respectively, linked with a common marker set of four co-segregating markers, ORS191, ORS316, ORS581, and ZVG61, in the distal side and one marker ORS464 in the proximal side. To identify new markers closer to the genes, sunflower RGC (resistance gene candidate) markers linked to the downy mildew R-gene Pl 8 and located at the same region as R 13a and R 13b were selected to screen the two F2 populations. The RGC markers RGC15/16 and a newly developed marker SUN14 designed from a BAC contig anchored by RGC251 further narrowed down the region flanking R 13a and R 13b to 1.1 and 0.1 cM, respectively. Both R 13a and R 13b are highly effective against all rust races

  17. Operational Testing of Satellite based Hydrological Model (SHM)

    Science.gov (United States)

    Gaur, Srishti; Paul, Pranesh Kumar; Singh, Rajendra; Mishra, Ashok; Gupta, Praveen Kumar; Singh, Raghavendra P.

    2017-04-01

    Incorporation of the concept of transposability in model testing is one of the prominent ways to check the credibility of a hydrological model. Successful testing ensures ability of hydrological models to deal with changing conditions, along with its extrapolation capacity. For a newly developed model, a number of contradictions arises regarding its applicability, therefore testing of credibility of model is essential to proficiently assess its strength and limitations. This concept emphasizes to perform 'Hierarchical Operational Testing' of Satellite based Hydrological Model (SHM), a newly developed surface water-groundwater coupled model, under PRACRITI-2 program initiated by Space Application Centre (SAC), Ahmedabad. SHM aims at sustainable water resources management using remote sensing data from Indian satellites. It consists of grid cells of 5km x 5km resolution and comprises of five modules namely: Surface Water (SW), Forest (F), Snow (S), Groundwater (GW) and Routing (ROU). SW module (functions in the grid cells with land cover other than forest and snow) deals with estimation of surface runoff, soil moisture and evapotranspiration by using NRCS-CN method, water balance and Hragreaves method, respectively. The hydrology of F module is dependent entirely on sub-surface processes and water balance is calculated based on it. GW module generates baseflow (depending on water table variation with the level of water in streams) using Boussinesq equation. ROU module is grounded on a cell-to-cell routing technique based on the principle of Time Variant Spatially Distributed Direct Runoff Hydrograph (SDDH) to route the generated runoff and baseflow by different modules up to the outlet. For this study Subarnarekha river basin, flood prone zone of eastern India, has been chosen for hierarchical operational testing scheme which includes tests under stationary as well as transitory conditions. For this the basin has been divided into three sub-basins using three flow

  18. Hvor mange alkoholikere har vi? Alkoholproblemer i Oslos befolkning

    Directory of Open Access Journals (Sweden)

    Hans Olav Fekjær

    2009-10-01

    Full Text Available  SAMMENDRAGI de siste tiårene har bekymringen for alkoholproblemer vært knyttet til begreper som "alkoholiker" eller "de somhar alkoholproblemer". Begrepene impliserer at de fleste problemene er langvarige tilstander hos en avgrenset,behandlingstrengende gruppe. Den foreliggende undersøkelsen var lagt opp som en post-enquete. Skjemaene blesendt til et representativt utvalg Oslo-borgere i alderen 18-59 år. En mottok 2051 skjemaer og oppnådde en svarprosentpå 77. Respondentene ble spurt om de hadde opplevet 8 typer skadevirkninger knyttet til sin alkoholbruk.Avhengig av antall skadevirkninger ble personens alkoholproblemer definert som moderate, betydelige eller store.Hvis "alkoholisme" defineres som å ha opplevet et visst antall av de 8 problemene, varierer antall "alkoholikere"dramatisk avhengig av antall skadevirkninger som kreves: Hvis det kreves 7 problemer, er færre enn 1% av dennebefolkningen alkoholikere. Hvis det kreves 3 problemer er 21% alkoholikere. Hyppigheten av alkoholproblemerreduseres gradvis med økende alder, fra 29% mellom 18 og 25 års alder til 8% mellom 45 og 60 år. De aller flestealkoholproblemer er ikke knyttet til daglig drikking eller til et svært høyt forbruk pr. år. De fleste som noen ganghar opplevet betydelige eller store problemer synes å "modne ut" av problemdrikking uten å stoppe å drikke oguten noen form for behandling. De fleste som har betydelige eller store problemer har ikke ønsket å kutte sinalkoholbruk ut eller sterkt ned. Blant dem som har ønsket det, har over 90% klart det helt eller delvis. Undersøkelsenbekrefter tidligere befolkningsstudier som indikerer at de fleste alkoholproblemer er spredt blant en storandel av den yngre mannlige befolkningen som stort sett synes å ha kontroll over sin alkoholbruk, ikke kan kallesavhengige og ikke kommer til alkoholistbehandling. Artikkelen drøfter hvilke konsekvenser dette har forsamfunnets strev for å redusere problemene.Fekjær HO

  19. Omnibus hypothesis testing in dominance-based ordinal multiple regression.

    Science.gov (United States)

    Long, Jeffrey D

    2005-09-01

    Often quantitative data in the social sciences have only ordinal justification. Problems of interpretation can arise when least squares multiple regression (LSMR) is used with ordinal data. Two ordinal alternatives are discussed, dominance-based ordinal multiple regression (DOMR) and proportional odds multiple regression. The Q2 statistic is introduced for testing the omnibus null hypothesis in DOMR. A simulation study is discussed that examines the actual Type I error rate and power of Q2 in comparison to the LSMR omnibus F test under normality and non-normality. Results suggest that Q2 has favorable sampling properties as long as the sample size-to-predictors ratio is not too small, and Q2 can be a good alternative to the omnibus F test when the response variable is non-normal. Copyright 2005 APA, all rights reserved.

  20. Syndromic Panel-Based Testing in Clinical Microbiology.

    Science.gov (United States)

    Ramanan, Poornima; Bryson, Alexandra L; Binnicker, Matthew J; Pritt, Bobbi S; Patel, Robin

    2018-01-01

    The recent development of commercial panel-based molecular diagnostics for the rapid detection of pathogens in positive blood culture bottles, respiratory specimens, stool, and cerebrospinal fluid has resulted in a paradigm shift in clinical microbiology and clinical practice. This review focuses on U.S. Food and Drug Administration (FDA)-approved/cleared multiplex molecular panels with more than five targets designed to assist in the diagnosis of bloodstream, respiratory tract, gastrointestinal, or central nervous system infections. While these panel-based assays have the clear advantages of a rapid turnaround time and the detection of a large number of microorganisms and promise to improve health care, they present certain challenges, including cost and the definition of ideal test utilization strategies (i.e., optimal ordering) and test interpretation. Copyright © 2017 American Society for Microbiology.

  1. Tests of beam-based alignement at FACET

    CERN Document Server

    Latina, A; Schulte, D; Adli, E

    2014-01-01

    The performance of future linear colliders will depend critically on beam-based alignment (BBA) and feedback systems, which will play a crucial role in guaranteeing the low emittance transport throughout such machines. BBA algorithms designed to improve the beam transmission in a linac by simultaneously optimising the trajectory and minimising the residual dispersion, have thoughtfully been studied in theory over the last years, and successfully verified experimentally. One such technique is called Dispersion-Free Steering (DFS). A careful study of the DFS performance at the SLAC test facility FACET lead us to design a beam-based technique specifically targeted to reduce the impact of transverse short-range wakefields, rather than of the dispersion, being the wakefields the limiting factor to the FACET performance. This technique is called Wakefield-Free Steering (WFS). The results of the first tests of WFS at FACET are presented in this paper.

  2. Generalized Correlation Coefficient Based on Log Likelihood Ratio Test Statistic

    Directory of Open Access Journals (Sweden)

    Liu Hsiang-Chuan

    2016-01-01

    Full Text Available In this paper, I point out that both Joe’s and Ding’s strength statistics can only be used for testing the pair-wise independence, and I propose a novel G-square based strength statistic, called Liu’s generalized correlation coefficient, it can be used to detect and compare the strength of not only the pair-wise independence but also the mutual independence of any multivariate variables. Furthermore, I proved that only Liu’s generalized correlation coefficient is strictly increasing on its number of variables, it is more sensitive and useful than Cramer’s V coefficient, in other words, Liu generalized correlation coefficient is not only the G-square based strength statistic, but also an improved statistic for detecting and comparing the strengths of deferent associations of any two or more sets of multivariate variables, moreover, this new strength statistic can also be tested by G2.

  3. Acoustic displacement triangle based on the individual element test

    Directory of Open Access Journals (Sweden)

    S. Correa

    Full Text Available A three node -displacement based- acoustic element is developed. In order to avoid spurious rotational modes, a higher order stiffness is introduced. This higher order stiffness is developed from an incompatible strain field which computes element volume changes under nodal rotational displacements fields. The higher order strain resulting from the incompatible strain field satisfies the Individual Element Test (IET requirements without affecting convergence. The higher order stiffness is modulated, element by element, with a factor. As a result, the displacement based formulation presented on this paper is capable of placing the spurious rotational modes above the range of the physical compressional modes that can be accurately calculated by the mesh.

  4. Detailed field test of yaw-based wake steering

    DEFF Research Database (Denmark)

    Fleming, P.; Churchfield, M.; Scholbrock, A.

    2016-01-01

    This paper describes a detailed field-test campaign to investigate yaw-based wake steering. In yaw-based wake steering, an upstream turbine intentionally misaligns its yaw with respect to the inflow to deflect its wake away from a downstream turbine, with the goal of increasing total power...... production. In the first phase, a nacelle-mounted scanning lidar was used to verify wake deflection of a misaligned turbine and calibrate wake deflection models. In the second phase, these models were used within a yaw controller to achieve a desired wake deflection. This paper details the experimental...

  5. DIAGNOSTIC TEST FOR GARCH MODELS BASED ON ABSOLUTE RESIDUAL AUTOCORRELATIONS

    Directory of Open Access Journals (Sweden)

    Farhat Iqbal

    2013-10-01

    Full Text Available In this paper the asymptotic distribution of the absolute residual autocorrelations from generalized autoregressive conditional heteroscedastic (GARCH models is derived. The correct asymptotic standard errors for the absolute residual autocorrelations are also obtained and based on these results, a diagnostic test for checking the adequacy of GARCH-type models are developed. Our results do not depend on the existence of higher moments and is therefore robust under heavy-tailed distributions.

  6. Computer Based Test Untuk Seleksi Masuk Politeknik Negeri Bengkalis

    OpenAIRE

    Agus Tedyyana; Danuri Danuri

    2017-01-01

    AbstrakPenyeleksian calon mahasiswa baru dapat dilakukan dengan aplikasi Computer Based Test (CBT). Metode yang digunakan meliputi teknik pengumpulan data, analisis sistem, model perancangan, implementasi dan pengujian. Penelitian ini menghasilkan aplikasi CBT dimana soal yang dimunculkan dari bank soal melalui proses pengacakan dengan tidak akan memunculkan soal yang sama dengan menggunakan metoda Fisher-Yates Shuffle. Dalam proses pengamanan informasi soal saat terhubung ke jaringan maka di...

  7. Strengthening Theoretical Testing in Criminology Using Agent-based Modeling

    OpenAIRE

    Johnson, S. D.; Groff, E.

    2014-01-01

    Objectives: The Journal of Research in Crime and Delinquency (JRCD) has published important contributions to both criminological theory and associated empirical tests. In this article, we consider some of the challenges associated with traditional approaches to social science research, and discuss a complementary approach that is gaining popularity—agent-based computational modeling—that may offer new opportunities to strengthen theories of crime and develop insights into phenomena of interes...

  8. Strengthening Theoretical Testing in Criminology Using Agent-based Modeling.

    Science.gov (United States)

    Johnson, Shane D; Groff, Elizabeth R

    2014-07-01

    The Journal of Research in Crime and Delinquency ( JRCD ) has published important contributions to both criminological theory and associated empirical tests. In this article, we consider some of the challenges associated with traditional approaches to social science research, and discuss a complementary approach that is gaining popularity-agent-based computational modeling-that may offer new opportunities to strengthen theories of crime and develop insights into phenomena of interest. Two literature reviews are completed. The aim of the first is to identify those articles published in JRCD that have been the most influential and to classify the theoretical perspectives taken. The second is intended to identify those studies that have used an agent-based model (ABM) to examine criminological theories and to identify which theories have been explored. Ecological theories of crime pattern formation have received the most attention from researchers using ABMs, but many other criminological theories are amenable to testing using such methods. Traditional methods of theory development and testing suffer from a number of potential issues that a more systematic use of ABMs-not without its own issues-may help to overcome. ABMs should become another method in the criminologists toolbox to aid theory testing and falsification.

  9. Standard Test Method for Preparing Aircraft Cleaning Compounds, Liquid Type, Water Base, for Storage Stability Testing

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2002-01-01

    1.1 This test method covers the determination of the stability in storage, of liquid, water-base chemical cleaning compounds, used to clean the exterior surfaces of aircraft. 1.2 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

  10. Inquiry-Based Instruction and High Stakes Testing

    Science.gov (United States)

    Cothern, Rebecca L.

    Science education is a key to economic success for a country in terms of promoting advances in national industry and technology and maximizing competitive advantage in a global marketplace. The December 2010 Program for International Student Assessment (PISA) ranked the United States 23rd of 65 countries in science. That dismal standing in science proficiency impedes the ability of American school graduates to compete in the global market place. Furthermore, the implementation of high stakes testing in science mandated by the 2007 No Child Left Behind (NCLB) Act has created an additional need for educators to find effective science pedagogy. Research has shown that inquiry-based science instruction is one of the predominant science instructional methods. Inquiry-based instruction is a multifaceted teaching method with its theoretical foundation in constructivism. A correlational survey research design was used to determine the relationship between levels of inquiry-based science instruction and student performance on a standardized state science test. A self-report survey, using a Likert-type scale, was completed by 26 fifth grade teachers. Participants' responses were analyzed and grouped as high, medium, or low level inquiry instruction. The unit of analysis for the achievement variable was the student scale score average from the state science test. Spearman's Rho correlation data showed a positive relationship between the level of inquiry-based instruction and student achievement on the state assessment. The findings can assist teachers and administrators by providing additional research on the benefits of the inquiry-based instructional method. Implications for positive social change include increases in student proficiency and decision-making skills related to science policy issues which can help make them more competitive in the global marketplace.

  11. Significance of Test-based Ratings for Metropolitan Boston Schools

    Directory of Open Access Journals (Sweden)

    Craig Bolon

    2001-10-01

    Full Text Available In 1998 Massachusetts began state-sponsored, annual achievement testing of all students in three public school grades. It has created a school and district rating system for which scores on these tests are the sole factor. It proposes to use tenth-grade test scores as a sole criterion for high school graduation, beginning with the class of 2003. The state is treating scores and ratings as though they were precise educational measures of high significance. A review of tenth-grade mathematics test scores from academic high schools in metropolitan Boston showed that statistically they are not. Community income is strongly correlated with test scores and accounted for more than 80 percent of the variance in average scores for a sample of Boston-area communities. Once community income was included in models, other factors--including percentages of students in disadvantaged populations, (Note 1 percentages receiving special education, percentages eligible for free or reduced price lunch, percentages with limited English proficiency, school sizes, school spending levels, and property values--all failed to associate substantial additional variance. Large uncertainties in residuals of school-averaged scores, after subtracting predictions based on community income, tend to make the scores ineffective for rating performance of schools. Large uncertainties in year-to-year score changes tend to make the score changes ineffective for measuring performance trends.

  12. Harnessing type I and type III CRISPR-Cas systems for genome editing

    DEFF Research Database (Denmark)

    Li, Yingjun; Pan, Saifu; Zhang, Yan

    2016-01-01

    CRISPR-Cas (clustered regularly interspaced short palindromic repeats-CRISPR-associated) systems are widespread in archaea and bacteria, and research on their molecular mechanisms has led to the development of genome-editing techniques based on a few Type II systems. However, there has not been any...... report on harnessing a Type I or Type III system for genome editing. Here, a method was developed to repurpose both CRISPR-Cas systems for genetic manipulation in Sulfolobus islandicus, a thermophilic archaeon. A novel type of genome-editing plasmid (pGE) was constructed, carrying an artificial mini-CRISPR...... and selectively retained as transformants. Using this strategy, different types of mutation were generated, including deletion, insertion and point mutations. We envision this method is readily applicable to different bacteria and archaea that carry an active CRISPR-Cas system of DNA interference provided...

  13. 14 CFR 29.785 - Seats, berths, litters, safety belts, and harnesses.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Seats, berths, litters, safety belts, and harnesses. 29.785 Section 29.785 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... and Cargo Accommodations § 29.785 Seats, berths, litters, safety belts, and harnesses. (a) Each seat...

  14. 14 CFR 121.311 - Seats, safety belts, and shoulder harnesses.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Seats, safety belts, and shoulder harnesses. 121.311 Section 121.311 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... § 121.311 Seats, safety belts, and shoulder harnesses. (a) No person may operate an airplane unless...

  15. 14 CFR 137.42 - Fastening of safety belts and shoulder harnesses.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Fastening of safety belts and shoulder harnesses. 137.42 Section 137.42 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... AGRICULTURAL AIRCRAFT OPERATIONS Operating Rules § 137.42 Fastening of safety belts and shoulder harnesses. No...

  16. 14 CFR 25.785 - Seats, berths, safety belts, and harnesses.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Seats, berths, safety belts, and harnesses. 25.785 Section 25.785 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... and Cargo Accommodations § 25.785 Seats, berths, safety belts, and harnesses. (a) A seat (or berth for...

  17. 14 CFR 27.785 - Seats, berths, litters, safety belts, and harnesses.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Seats, berths, litters, safety belts, and harnesses. 27.785 Section 27.785 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... Cargo Accommodations § 27.785 Seats, berths, litters, safety belts, and harnesses. (a) Each seat, safety...

  18. 14 CFR 23.785 - Seats, berths, litters, safety belts, and shoulder harnesses.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Seats, berths, litters, safety belts, and shoulder harnesses. 23.785 Section 23.785 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT... belts, and shoulder harnesses. There must be a seat or berth for each occupant that meets the following...

  19. 14 CFR 135.171 - Shoulder harness installation at flight crewmember stations.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Shoulder harness installation at flight crewmember stations. 135.171 Section 135.171 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... ON BOARD SUCH AIRCRAFT Aircraft and Equipment § 135.171 Shoulder harness installation at flight...

  20. 14 CFR 91.107 - Use of safety belts, shoulder harnesses, and child restraint systems.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Use of safety belts, shoulder harnesses, and child restraint systems. 91.107 Section 91.107 Aeronautics and Space FEDERAL AVIATION... OPERATING AND FLIGHT RULES Flight Rules General § 91.107 Use of safety belts, shoulder harnesses, and child...

  1. 14 CFR 105.43 - Use of single-harness, dual-parachute systems.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Use of single-harness, dual-parachute systems. 105.43 Section 105.43 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... Packing § 105.43 Use of single-harness, dual-parachute systems. No person may conduct a parachute...

  2. Når sex er en ret, hvem har så pligt?

    DEFF Research Database (Denmark)

    Munk-Madsen, Eva

    2007-01-01

    Socialministeriet har fastslået i en vejledning, at samfundet har omsorgspligt for funktionshæmmedes borgeres  seksuelle udfoldelsesmulighder. Tre grupper er udpeget som dem der skal varetage denne omsorgspligt på samfundets vegne: ansatte hjælpepersoner, seksualvejledere og prostituerede. I modt...

  3. 42 CFR 84.173 - Harnesses; installation and construction; minimum requirements.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Harnesses; installation and construction; minimum... SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Non-Powered Air-Purifying Particulate Respirators § 84.173 Harnesses; installation and...

  4. 42 CFR 84.133 - Harnesses; installation and construction; minimum requirements.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Harnesses; installation and construction; minimum... SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Supplied-Air Respirators § 84.133 Harnesses; installation and construction; minimum requirements...

  5. 42 CFR 84.116 - Harnesses; installation and construction; minimum requirements.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Harnesses; installation and construction; minimum... SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Gas Masks § 84.116 Harnesses; installation and construction; minimum requirements. (a) Each gas...

  6. 42 CFR 84.196 - Harnesses; installation and construction; minimum requirements.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Harnesses; installation and construction; minimum... SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Chemical Cartridge Respirators § 84.196 Harnesses; installation and construction; minimum...

  7. 42 CFR 84.73 - Harnesses; installation and construction; minimum requirements.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Harnesses; installation and construction; minimum... OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Self-Contained Breathing Apparatus § 84.73 Harnesses; installation and construction; minimum requirements. (a...

  8. Testing GNSS ionosphere models based on the position domain

    Science.gov (United States)

    Orus-Perez, Raul; Rovira, Adria

    2017-04-01

    As is well know, the ionosphere is one of the main contributors to the navigation error of single-frequency users. Currently, there are many models available for correcting the ionosphere delay. Thus, the different GNSS provide its own ionosphere corrections in the Signal-in-Space as for instance, NeQuick G for Galileo or Klobuchar for GPS. Other sources for ionosphere corrections are the Satellite Based Augmentation Systems (i.e. EGNOS or WAAS), Global Ionospheric Maps (i.e. provided by IGS), regional maps and even climatological models, like NeQuick or IRI. With this large variety of models, there have been a lot of efforts to define a suitable strategy to test the accuracy of the different models. Usually, this testing has been done by computing a "reference ionosphere", using all kind of GNSS techniques, using ionosonde data or using altimeter data. These techniques are not bias free and they may raise questions on which is the absolute accuracy they achieve. In order to complement these tests, a new methodology has been developed to test ionosphere models for GNSS. This methodology is based on the position domain, modeling the observables on each frequency with geodetic accuracy, and then to combine the obtained least square solutions to determine the ionosphere error. The results of the testing for different GIMs from IGS and different Signal-in-Space models (GPS, Galileo, and EGNOS) will be presented for 2 years of the last Solar Maximum with more than 40 receivers worldwide. The weaknesses and strengths of the new methodology will also be shown to get a comprehensive idea of its capabilities.

  9. A computer vision based candidate for functional balance test.

    Science.gov (United States)

    Nalci, Alican; Khodamoradi, Alireza; Balkan, Ozgur; Nahab, Fatta; Garudadri, Harinath

    2015-08-01

    Balance in humans is a motor skill based on complex multimodal sensing, processing and control. Ability to maintain balance in activities of daily living (ADL) is compromised due to aging, diseases, injuries and environmental factors. Center for Disease Control and Prevention (CDC) estimate of the costs of falls among older adults was $34 billion in 2013 and is expected to reach $54.9 billion in 2020. In this paper, we present a brief review of balance impairments followed by subjective and objective tools currently used in clinical settings for human balance assessment. We propose a novel computer vision (CV) based approach as a candidate for functional balance test. The test will take less than a minute to administer and expected to be objective, repeatable and highly discriminative in quantifying ability to maintain posture and balance. We present an informal study with preliminary data from 10 healthy volunteers, and compare performance with a balance assessment system called BTrackS Balance Assessment Board. Our results show high degree of correlation with BTrackS. The proposed system promises to be a good candidate for objective functional balance tests and warrants further investigations to assess validity in clinical settings, including acute care, long term care and assisted living care facilities. Our long term goals include non-intrusive approaches to assess balance competence during ADL in independent living environments.

  10. A Universal Motor Performance Test System Based on Virtual Instrument

    Directory of Open Access Journals (Sweden)

    Wei Li

    2014-09-01

    Full Text Available With the development of technology universal motors play a more and more important role in daily life and production, they have been used in increasingly wide field and the requirements increase gradually. How to control the speed and monitor the real-time temperature of motors are key issues. The cost of motor testing system based on traditional technology platform is very high in many reasons. In the paper a universal motor performance test system which based on virtual instrument is provided. The system achieves the precise control of the current motor speed and completes the measurement of real-time temperature of motor bearing support in order to realize the testing of general-purpose motor property. Experimental result shows that the system can work stability in controlling the speed and monitoring the real-time temperature. It has advantages that traditional using of SCM cannot match in speed, stability, cost and accuracy aspects. Besides it is easy to expand and reconfigure.

  11. Prevailence of Patch Test Positivity with Some Bases

    Directory of Open Access Journals (Sweden)

    J S Pasricha

    1987-01-01

    Full Text Available To evaluate the suitability of some chemicals to act as bases for antigens for patch tests, patch tests were performed with these agents in patients having contact dermatitis. Propylene glycol′used as such produced positive reactions in 25 (50% patients of which 12 were 2 + or more, polyethylene glycol 200 produced positive reactions in 9 (18% cases of which 4 cases were 2 + or more, a mixture of liquid paraffin and hard paraffin gave rise to positive reactions in 10 (10% cases 3 of these being 2 +, a mixture of liquid paraffin and bees wax was positive in 14 (14,Yo cases 3 of these being 2 +, yellow petrolatum was positive in 4 (8% cases, one of which was 2 +, white petrolatum was positive in S (6% cases all of these being + reactions only, and glycerol gave rise to a I + reaction in only one (2% caw. In tropical countries, water should be as base for as many antigens as possible for others, a control test with the b must be included.

  12. Quality Testing of Artemisinin-Based Antimalarial Drugs in Myanmar.

    Science.gov (United States)

    Guo, Suqin; Kyaw, Myat Phone; He, Lishan; Min, Myo; Ning, Xiangxue; Zhang, Wei; Wang, Baomin; Cui, Liwang

    2017-10-01

    Artemisinin-based combination therapies are the frontline treatment of Plasmodium falciparum malaria. The circulation of falsified and substandard artemisinin-based antimalarials in Southeast Asia has been a major predicament for the malaria elimination campaign. To provide an update of this situation, we purchased 153 artemisinin-containing antimalarials, as convenience samples, in private drug stores from different regions of Myanmar. The quality of these drugs in terms of their artemisinin derivative content was tested using specific dipsticks for these artemisinin derivatives, as point-of-care devices. A subset of these samples was further tested by high-performance liquid chromatography (HPLC). This survey identified that > 35% of the collected drugs were oral artesunate and artemether monotherapies. When tested with the dipsticks, all but one sample passed the assays, indicating that the detected artemisinin derivative content corresponded approximately to the labeled contents. However, one artesunate injection sample was found to contain no active ingredient at all by the dipstick assay and subsequent HPLC analysis. The continued circulation of oral monotherapies and the description, for the first time, of falsified parenteral artesunate provides a worrisome picture of the antimalarial drug quality in Myanmar during the malaria elimination phase, a situation that deserves more oversight from regulatory authorities.

  13. Vision-based Ground Test for Active Debris Removal

    Directory of Open Access Journals (Sweden)

    Seong-Min Lim

    2013-12-01

    Full Text Available Due to the continuous space development by mankind, the number of space objects including space debris in orbits around the Earth has increased, and accordingly, difficulties of space development and activities are expected in the near future. In this study, among the stages for space debris removal, the implementation of a vision-based approach technique for approaching space debris from a far-range rendezvous state to a proximity state, and the ground test performance results were described. For the vision-based object tracking, the CAM-shift algorithm with high speed and strong performance, and the Kalman filter were combined and utilized. For measuring the distance to a tracking object, a stereo camera was used. For the construction of a low-cost space environment simulation test bed, a sun simulator was used, and in the case of the platform for approaching, a two-dimensional mobile robot was used. The tracking status was examined while changing the position of the sun simulator, and the results indicated that the CAM-shift showed a tracking rate of about 87% and the relative distance could be measured down to 0.9 m. In addition, considerations for future space environment simulation tests were proposed.

  14. Standardized childhood fitness percentiles derived from school-based testing.

    Science.gov (United States)

    Carrel, Aaron L; Bowser, John; White, Doug; Moberg, D Paul; Weaver, Brian; Hisgen, Jon; Eickhoff, Jens; Allen, David B

    2012-07-01

    To develop a statewide school-based program of measuring and reporting cardiovascular fitness levels in children, and to create age- and sex-specific cardiovascular fitness percentile-based distribution curves. A pilot study validated cardiovascular fitness assessment with Progressive Aerobic Cardiovascular Endurance Run (PACER) testing as an accurate predictor of cardiovascular fitness measured by maximal oxygen consumption treadmill testing. Schools throughout the state were then recruited to perform PACER and body mass index (BMI) measurement and report de-identified data to a centralized database. Data on 20 631 individual students with a mean age 12.1 ± 2.0 years, BMI of 21.4 ± 5.1, and a cardiovascular fitness measured with PACER of 29.7 ± 18.2 laps (estimated maximal oxygen consumption of 36.5 mL/kg/min) were submitted for analysis. Standardized fitness percentiles were calculated for age and sex. This study demonstrates the feasibility of performing, reporting, and recording annual school-based assessments of cardiovascular fitness to develop standardized childhood fitness percentiles on the basis of age and sex. Such data can be useful in comparing populations and assessing initiatives that aim to improve childhood fitness. Because health consequences of obesity result from both adiposity and physical inactivity, supplementation of BMI measurement with tracking of cardiovascular fitness adds a valuable tool for large-scale health assessment. Published by Mosby, Inc.

  15. Test-Driven, Model-Based Systems Engineering

    DEFF Research Database (Denmark)

    Munck, Allan

    . This thesis concerns methods for identifying, selecting and implementing tools for various aspects of model-based systems engineering. A comprehensive method was proposed that include several novel steps such as techniques for analyzing the gap between requirements and tool capabilities. The method...... was verified with good results in two case studies for selection of a traceability tool (single-tool scenario) and a set of modeling tools (multi-tool scenarios). Models must be subjected to testing to allow engineers to predict functionality and performance of systems. Test-first strategies are known......Hearing systems have evolved over many years from simple mechanical devices (horns) to electronic units consisting of microphones, amplifiers, analog filters, loudspeakers, batteries, etc. Digital signal processors replaced analog filters to provide better performance end new features. Central...

  16. Bond strength test of acrylic artificial teeth with prosthetic base

    Directory of Open Access Journals (Sweden)

    Erna Kurnikasari

    2008-07-01

    Full Text Available Denture consists of acrylic artificial teeth and acrylic prothesis base bond chemically with a bond strength of 315 kgF/cm2. Most of the commercial acrylic artificial teeth do not specify their specifications and all of those acrylic artificial teeth do not include mechanical data (bond strength. The aim of this study is to discover which acrylic artificial teeth meet ADA specification no. 15. This study is a descriptive analytic study performed to 5 acrylic artificial teeth posterior brands commonly used by dentists and technicians. From each brand, 3 sample teeth were taken. The acrylic artificial teeth were prepared into a rectangular shape and were attached between acrylic prothesis base simulation and jigs. The sample was given tensile load using a Universal Testing Machine. The amount of force that causes the teeth to be fractured was recorded and the bond strength was calculated. The results of the study show that the average value for the five acrylic artificial teeth for the five brands were as followed: Brand A, 125.993 kgF/cm2; B, 188.457 kgF/cm2; C, 175.880 kgF/cm2; D, 153.373 kgF/cm2; E, 82.839 kgF/cm2. The data can be tested statistically by using One Way ANOVA test and Dunnett test (alpha = 0.05. From the study, it is concluded that the five acrylic artificial teeth have a bond strength below the ADA specification no. 15.

  17. Introducing the Geneva emotion recognition test: an example of Rasch-based test development.

    Science.gov (United States)

    Schlegel, Katja; Grandjean, Didier; Scherer, Klaus R

    2014-06-01

    Existing tests to measure the ability to recognize other people's emotional expressions (emotion recognition ability [ERA]) mostly focus on a single modality (usually the face) and include only a small number of emotions, restricting their ecological validity. Further, their reliability is often unsatisfactory. The goal of the present study was to develop a new ERA test (Geneva Emotion Recognition Test [GERT]) that (a) features dynamic and multimodal actor portrayals (short videos with sound), (b) contains a large number of emotions, and (c) is based on modern psychometric principles (item response theory). We asked 295 participants to watch 108 actor portrayals and to choose, for each portrayal, which of 14 emotions had been expressed by the actor. We then applied the Rasch model independently to each of the 14 emotion portrayal subsets to select 83 final items for the GERT. Results showed that the model fits the emotion subtests and the overall GERT and that measurement precision is satisfactory. Consistent with previous findings, we found a decline in ERA with increasing age and an ERA advantage for women. To conclude, the GERT is a promising instrument to measure ERA in a more ecologically valid and comprehensive fashion than previous tests.

  18. Development Testing of 1-Newton ADN-Based Rocket Engines

    Science.gov (United States)

    Anflo, K.; Gronland, T.-A.; Bergman, G.; Nedar, R.; Thormählen, P.

    2004-10-01

    With the objective to reduce operational hazards and improve specific and density impulse as compared with hydrazine, the Research and Development (R&D) of a new monopropellant for space applications based on AmmoniumDiNitramide (ADN), was first proposed in 1997. This pioneering work has been described in previous papers1,2,3,4 . From the discussion above, it is clear that cost savings as well as risk reduction are the main drivers to develop a new generation of reduced hazard propellants. However, this alone is not enough to convince a spacecraft builder to choose a new technology. Cost, risk and schedule reduction are good incentives, but a spacecraft supplier will ask for evidence that this new propulsion system meets a number of requirements within the following areas: This paper describes the ongoing effort to develop a storable liquid monopropellant blend, based on AND, and its specific rocket engines. After building and testing more than 20 experimental rocket engines, the first Engineering Model (EM-1) has now accumulated more than 1 hour of firing-time. The results from test firings have validated the design. Specific impulse, combustion stability, blow-down capability and short pulse capability are amongst the requirements that have been demonstrated. The LMP-103x propellant candidate has been stored for more than 1 year and initial material compatibility screening and testing has started. 1. Performance &life 2. Impact on spacecraft design &operation 3. Flight heritage Hereafter, the essential requirements for some of these areas are outlined. These issues are discussed in detail in a previous paper1 . The use of "Commercial Of The Shelf" (COTS) propulsion system components as much as possible is essential to minimize the overall cost, risk and schedule. This leads to the conclusion that the Technology Readiness Level (TRL) 5 has been reached for the thruster and propellant. Furthermore, that the concept of ADN-based propulsion is feasible.

  19. IURead: a new computer-based reading test.

    Science.gov (United States)

    Xu, Renfeng; Bradley, Arthur

    2015-09-01

    To develop a computer-based single sentence reading test especially designed for clinical research enabling multiple repeat trials without reusing the same sentences. We initially developed 422 sentences, with an average of 60 characters and 12 words. Presentation controls were improved by employing computer-based testing and the oral reading was recorded by visual inspection of digital audio recordings. Variability in reading speed of normally sighted adults between sentences, between charts, between subjects, between formats, and between display devices was quantified. The impact of display size and pixel resolution on test geometry was assessed, and the impact of reduced retinal image quality and retinal illuminance were compared for reading and standard letter acuities. Eleven visually normal subjects (age: 18-60 years) participated in this study. Stopwatch timing of sentences reliably underestimated reading times by about 0.3 s, and exhibited coefficients of repeatability 17 times larger than those estimated from visual inspection of digital recordings. A slight relaxing of the lexical content constraints had no effect on reading speed; neither did sentence format (single vs three lines) or display size or distance. Within subject standard deviations of reading speed for different sentences were small (between 6% and 9% of the mean speed) requiring only small samples sizes to achieve typical statistical reliability and power when comparing conditions within individual subjects. The greater variability associated with stopwatch timing necessitates larger sample sizes. As defocus and light level were varied, reading acuity and standard letter acuity were highly correlated (r(2)  = 0.99), and reading acuity was slightly better. A computer-based IURead reading test provides a useful reading speed and reading acuity tool for clinical research involving multiple conditions and repeat testing of individual subjects. Ready to use IURead files for use with a

  20. Approximate Testing Equivalence Based on Time, Probability, and Observed Behavior

    Directory of Open Access Journals (Sweden)

    Alessandro Aldini

    2010-06-01

    Full Text Available Several application domains require formal but flexible approaches to the comparison problem. Different process models that cannot be related by behavioral equivalences should be compared via a quantitative notion of similarity, which is usually achieved through approximation of some equivalence. While in the literature the classical equivalence subject to approximation is bisimulation, in this paper we propose a novel approach based on testing equivalence. As a step towards flexibility and usability, we study different relaxations taking into account orthogonal aspects of the process observations: execution time, event probability, and observed behavior. In this unifying framework, both interpretation of the measures and decidability of the verification algorithms are discussed.

  1. Ultrasound-based testing of tendon mechanical properties

    DEFF Research Database (Denmark)

    Seynnes, O R; Bojsen-Møller, J.; Albracht, K

    2015-01-01

    In the past 20 years, the use of ultrasound-based methods has become a standard approach to measure tendon mechanical properties in vivo. Yet the multitude of methodological approaches adopted by various research groups probably contribute to the large variability of reported values. The technique......, or signal synchronization; and 2) in physiological considerations related to the viscoelastic behavior or length measurements of tendons. Hence, the purpose of the present review is to assess and discuss the physiological and technical aspects connected to in vivo testing of tendon mechanical properties...

  2. Automation of Flight Software Regression Testing

    Science.gov (United States)

    Tashakkor, Scott B.

    2016-01-01

    NASA is developing the Space Launch System (SLS) to be a heavy lift launch vehicle supporting human and scientific exploration beyond earth orbit. SLS will have a common core stage, an upper stage, and different permutations of boosters and fairings to perform various crewed or cargo missions. Marshall Space Flight Center (MSFC) is writing the Flight Software (FSW) that will operate the SLS launch vehicle. The FSW is developed in an incremental manner based on "Agile" software techniques. As the FSW is incrementally developed, testing the functionality of the code needs to be performed continually to ensure that the integrity of the software is maintained. Manually testing the functionality on an ever-growing set of requirements and features is not an efficient solution and therefore needs to be done automatically to ensure testing is comprehensive. To support test automation, a framework for a regression test harness has been developed and used on SLS FSW. The test harness provides a modular design approach that can compile or read in the required information specified by the developer of the test. The modularity provides independence between groups of tests and the ability to add and remove tests without disturbing others. This provides the SLS FSW team a time saving feature that is essential to meeting SLS Program technical and programmatic requirements. During development of SLS FSW, this technique has proved to be a useful tool to ensure all requirements have been tested, and that desired functionality is maintained, as changes occur. It also provides a mechanism for developers to check functionality of the code that they have developed. With this system, automation of regression testing is accomplished through a scheduling tool and/or commit hooks. Key advantages of this test harness capability includes execution support for multiple independent test cases, the ability for developers to specify precisely what they are testing and how, the ability to add

  3. Gas identification field test based on FTIR imaging spectrometer

    Science.gov (United States)

    Wang, Chensheng; Liu, Xingchao; Zhang, Zhijie; Yu, Hui

    2017-10-01

    Gas detection and identification is based on the spectral absorption peak feature, which is acquired by the spectrometer. FTIR imaging spectrometer has the advantages of high spectral resolution and good sensitivity, which are both suitable for the unknown or mixture gas identification applications, such as plume pollution monitoring, chemical agents detection and leakage detection. According to the application requirement, a dual band FTIR imaging spectrometer has been developed and verified. This FTIR imaging spectrometer combines the infrared thermal imaging sensor and Michelson interferometer to form the three dimensional data cube. Based on this instrument, the theoretical analysis and algorithm is introduced, and the numerical method is explained to illuminate the basic idea in gas identification based on spectral features. After that, the field verification test is setup and completed. Firstly, the FTIR imaging spectrometer is used to detect SF6, NH3 and the mixture gas, while the gas is exhausted out from the storage vase with a specific speed. Secondly, the instrument is delivered to the industrial area to monitor the plume emission, and analyze the components in plume. Finally, the instrument is utilized to monitoring the oil spill in ocean, and the practical maritime trial is realized. Further, the gas concentration evaluation method is discussed. Quantitative issue in gas identification is an important topic. The test results show that, based on the gas identification method introduced in this paper, FTIR imaging spectrometer can be utilized to identify the unknown gas or mixture gas in real time. The instrument will play a key role in environmental emergency and monitoring application.

  4. [ALPHA-fitness test battery: health-related field-based fitness tests assessment in children and adolescents].

    Science.gov (United States)

    Ruiz, J R; España Romero, V; Castro Piñero, J; Artero, E G; Ortega, F B; Cuenca García, M; Jiménez Pavón, D; Chillón, P; Girela Rejón, Ma J; Mora, J; Gutiérrez, A; Suni, J; Sjöstrom, M; Castillo, M J

    2011-01-01

    Hereby we summarize the work developed by the ALPHA (Assessing Levels of Physical Activity) Study and describe the tests included in the ALPHA health-related fitness test battery for children and adolescents. The evidence-based ALPHA-Fitness test battery include the following tests: 1) the 20 m shuttle run test to assess cardiorespiratory fitness; 2) the handgrip strength and 3) standing broad jump to assess musculoskeletal fitness, and 4) body mass index, 5) waist circumference; and 6) skinfold thickness (triceps and subscapular) to assess body composition. Furthermore, we include two versions: 1) the high priority ALPHA health-related fitness test battery, which comprises all the evidence-based fitness tests except the measurement of the skinfold thickness; and 2) the extended ALPHA health-related fitness tests battery for children and adolescents, which includes all the evidence-based fitness tests plus the 4 x 10 m shuttle run test to assess motor fitness.

  5. Blind Test of Physics-Based Prediction of Protein Structures

    Science.gov (United States)

    Shell, M. Scott; Ozkan, S. Banu; Voelz, Vincent; Wu, Guohong Albert; Dill, Ken A.

    2009-01-01

    We report here a multiprotein blind test of a computer method to predict native protein structures based solely on an all-atom physics-based force field. We use the AMBER 96 potential function with an implicit (GB/SA) model of solvation, combined with replica-exchange molecular-dynamics simulations. Coarse conformational sampling is performed using the zipping and assembly method (ZAM), an approach that is designed to mimic the putative physical routes of protein folding. ZAM was applied to the folding of six proteins, from 76 to 112 monomers in length, in CASP7, a community-wide blind test of protein structure prediction. Because these predictions have about the same level of accuracy as typical bioinformatics methods, and do not utilize information from databases of known native structures, this work opens up the possibility of predicting the structures of membrane proteins, synthetic peptides, or other foldable polymers, for which there is little prior knowledge of native structures. This approach may also be useful for predicting physical protein folding routes, non-native conformations, and other physical properties from amino acid sequences. PMID:19186130

  6. Blind test of physics-based prediction of protein structures.

    Science.gov (United States)

    Shell, M Scott; Ozkan, S Banu; Voelz, Vincent; Wu, Guohong Albert; Dill, Ken A

    2009-02-01

    We report here a multiprotein blind test of a computer method to predict native protein structures based solely on an all-atom physics-based force field. We use the AMBER 96 potential function with an implicit (GB/SA) model of solvation, combined with replica-exchange molecular-dynamics simulations. Coarse conformational sampling is performed using the zipping and assembly method (ZAM), an approach that is designed to mimic the putative physical routes of protein folding. ZAM was applied to the folding of six proteins, from 76 to 112 monomers in length, in CASP7, a community-wide blind test of protein structure prediction. Because these predictions have about the same level of accuracy as typical bioinformatics methods, and do not utilize information from databases of known native structures, this work opens up the possibility of predicting the structures of membrane proteins, synthetic peptides, or other foldable polymers, for which there is little prior knowledge of native structures. This approach may also be useful for predicting physical protein folding routes, non-native conformations, and other physical properties from amino acid sequences.

  7. Ageing tests study on wood-based sandwich panels

    Directory of Open Access Journals (Sweden)

    Mateo, Raquel

    2011-12-01

    Full Text Available Composite lightweight wood panels are being increasingly used in construction in Spain. Their growing use should be accompanied by necessary guarantees based on studies of their properties. As it is prescriptive and in addition to others tests, in the present work is examinated the durability of these panels when exposed to the climatic conditions, a characteristic of great importance for wood products, according to Guide ETAG 016, the current standard defining the ageing tests to be used. However, due to the use class of this material, there are indications that the testing outlined in this Guide is inappropriate for assessing the ageing of wood-based sandwich panels. Alternative tests are here proposed that recreate rather better the real conditions under which these products are used. Covering the samples in a waterproof sheeting permeable to the outward movement of water vapour, which is in fact used in the installation, provided the best procedure for testing these panels.

    Los paneles sándwich de madera son un producto de creciente aplicación en la edificación de nuestro país. Este ascendente uso del material debe estar acompañado de las garantías necesarias avaladas por un estudio previo de sus prestaciones. Como es preceptivo y entre otros, se evalúa su durabilidad frente a las condiciones climatológicas, clave en los productos derivados de la madera, acorde a la normativa actual definida con tal fin, la Guía ETAG 016. Sin embargo, debido a la clase de uso del material, se ha detectado que dicha normativa tal y como está concebida no es capaz de valorar su envejecimiento adecuadamente. En este trabajo se proponen ensayos alternativos al establecido tras exhaustivos análisis que recrean las condiciones reales de uso y más acordes a los productos de madera. Se concluye que la incorporación de una lámina impermeable pero permeable al vapor de agua hacia el exterior, como las utilizadas en el montaje, aportan el mejor

  8. Harnessing and understanding feedback technology in applied settings.

    Science.gov (United States)

    Phillips, Elissa; Farrow, Damian; Ball, Kevin; Helmer, Richard

    2013-10-01

    Research on the influence of augmented feedback effects on both skill learning and performance has been examined from two differing positions, generally reflective of two core movement science disciplines: motor learning and biomechanics. The motor learning approach has been to examine the content and timing of feedback under tightly controlled laboratory settings, with a focus on simple tasks and the influence of movement outcome feedback. At the other end of the spectrum are biomechanical approaches, which have been primarily devoted to demonstrating the capacity of measurement technology to quantify and report on movement pattern effectiveness. This review highlights the gap left by these two approaches and argues that advancement of our understanding of feedback application in practical settings requires a shift towards a multi-disciplinary focus. A particular focus of the review is on how researchers and practitioners need to harness our understanding and subsequent application of the emergent feedback technologies most prevalent in elite sport settings and clinical sports medicine. We highlight important considerations for future applied multidisciplinary research driven by relevant theory and methodological design to more comprehensively capture how feedback systems can be used to facilitate the development of skilled performance.

  9. Harnessing the Therapeutic Potential of Th17 Cells

    Directory of Open Access Journals (Sweden)

    Jonas Bystrom

    2015-01-01

    Full Text Available Th17 cells provide protective immunity to infections by fungi and extracellular bacteria as well as cancer but are also involved in chronic inflammation. The cells were first identified by their ability to produce interleukin 17A (IL-17A and, subsequently, associated with chronic inflammation and autoimmunity. Th17 cells have some gene profile similarity with stem cells and can remain dormant in mucosal tissues for long periods. Indeed, recent studies suggest that functionally distinct subsets of pro- and anti-inflammatory Th17 cells can interchange phenotype and functions. For development, Th17 cells require activation of the transcription factors STAT3 and RORγt while RUNX1, c-Maf, and Aiolos are involved in changes of phenotype/functions. Attempts to harness Th17 cells against pathogens and cancer using vaccination strategies are being explored. The cells gain protective abilities when induced to produce interferon γ (IFNγ. In addition, treatment with antibodies to IL-17 is effective in treating patients with psoriasis, psoriatic arthritis, and refectory rheumatoid arthritis. Moreover, since RORγt is a nuclear receptor, it is likely to be a potential future drug target for modulating Th17 functions. This review explores pathways through which Th17 subsets are induced, the molecular basis of their plasticity, and potential therapeutic strategies for their modulation in diseases.

  10. Biology-oriented synthesis: harnessing the power of evolution.

    Science.gov (United States)

    van Hattum, Hilde; Waldmann, Herbert

    2014-08-27

    For scientists to gain a better understanding of nature, biological research is greatly aided by small-molecule modulators that perturb protein activity without fundamentally altering the underlying biological systems. The number of possible interfering molecules, however, is so vast that, due to limitations in existing matter and time required for synthesis, they cannot be covered comprehensively. Because proteins and their cognate natural product ligands and substrates co-evolved, these naturally occurring ligands can serve as structural starting points to explore the biologically relevant chemical space. To this end, known natural products are structurally classified on the basis of their core scaffolds and hierarchically arranged in the "natural product tree", which can be annotated for bioactivity and intuitively navigated with currently available software. Biologically relevant scaffolds inspire the synthesis of compound libraries enriched in biological activity. This Perspective describes the development of "biology-oriented synthesis" as a guiding principle to harness the power of evolution in the quest for novel bioactive small molecules for chemical biology research and drug discovery.

  11. Mic Flocks in the Cloud: Harnessing Mobile Ubiquitous Sensor Networks

    Science.gov (United States)

    Garces, M. A.; Christe, A.

    2015-12-01

    Smartphones provide a commercial, off-the-shelf solution to capture, store, analyze, and distribute infrasound using on-board or external microphones (mics) as well as on-board barometers. Free iOS infrasound apps can be readily downloaded from the Apple App Store, and Android versions are in progress. Infrasound propagates for great distances, has low sample rates, and provides a tractable pilot study scenario for open distributed sensor networks at regional and global scales using one of the most ubiquitous sensors on Earth - microphones. Data collection is no longer limited to selected vendors at exclusive prices: anybody on Earth can record and stream infrasound, and the diversity of recording systems and environments is rapidly expanding. Global deployment may be fast and easy (www.redvox.io), but comes with the cost of increasing data volume, velocity, variety, and complexity. Flocking - the collective motion of mobile agents - is a natural human response to threats or events of interest. Anticipating, modeling and harnessing flocking sensor topologies will be necessary for adaptive array and network processing. The increasing data quantity and complexity will exceed the processing capacity of human analysts and most research servers. We anticipate practical real-time applications will require the on-demand adaptive scalability and resources of the Cloud. Cloud architectures for such heterogeneous sensor networks will consider eventual integration into the Global Earth Observation System of Systems (GEOSS).

  12. The globalization of health research: harnessing the scientific diaspora.

    Science.gov (United States)

    Anand, Nalini P; Hofman, Karen J; Glass, Roger I

    2009-04-01

    The scientific diaspora is a unique resource for U.S. universities. By drawing on the expertise, experience, and catalytic potential of diaspora scientists, universities can capitalize more fully on their diverse intellectual resources to make lasting contributions to global health. This article examines the unique contributions of the diaspora in international research collaborations, advantages of harnessing the diaspora and benefits to U.S. universities of fostering these collaborations, challenges faced by scientists who want to work with their home countries, examples of scientists engaging with their home countries, and specific strategies U.S. universities and donors can implement to catalyze these collaborations. The contributions of the diaspora to the United States are immense: International students enrolled in academic year 2007-2008 contributed an estimated $15 billion to the U.S. economy. As scientific research becomes increasingly global, the percentage of scientific publications with authors from foreign countries has grown from 8% in 1988 to 20% in 2005. Diaspora scientists can help build trusting relationships with scientists abroad, and international collaborations may improve the health of underserved populations at home. Although opportunities for diaspora networks are increasing, most home countries often lack enabling policies, infrastructure, and resources to effectively utilize their diaspora communities abroad. This article examines how some governments have successfully mobilized their scientific diaspora to become increasingly engaged in their national research agendas. Recommendations include specific strategies, including those that encourage U.S. universities to promote mini-sabbaticals and provide seed funding and flexible time frames.

  13. Gigantic blue shift of the H-Ar stretch vibration in pi hydrogen-bonded C(2)H(2)...HArCCF complex.

    Science.gov (United States)

    Cheng, Jianbo; Wang, Yilei; Li, Qingzhong; Liu, Zhenbo; Li, Wenzuo; Gong, Baoan

    2009-04-30

    Quantum chemical calculations have been performed to study the structure and properties of the pi hydrogen-bonded complex formed between acetylene and HArCCF at the MP2/6-311++G(2d,2p) level. The C(2)H(2)...HCCF and C(2)H(2)...HCCArF complexes were also studied for comparison with the C(2)H(2)...HArCCF complex. The basis set superposition errors (BSSE)-counterpoise corrected potential-energy surface (PES) has a larger influence on the structure and properties of the C(2)H(2)...HArCCF complex than those of the C(2)H(2)...HCCF and C(2)H(2)...HCCArF complexes. The C(2)H(2)...HArCCF complex exhibits a very large harmonic vibrational frequency blue shift of 574 cm(-1) for the H-Ar stretch, whereas the C(2)H(2)...HCCF and C(2)H(2)...HCCArF complexes exhibit a small red shift of 35 and 47 cm(-1) for the H-C stretch, respectively; upon complexation the IR intensity decreases in the former, whereas it increases in the latter. The origin of the frequency shift and nature of the hydrogen bond in these complexes have been unveiled with the natural bond orbital analysis and energy decomposition.

  14. Spelberoendets problematik : En hermeneutisk studie om hur människor som har ett spelberoende upplever sig avvikande i vardagslivet

    OpenAIRE

    Bienkowski, Allan

    2016-01-01

    Detta arbete har tagit upp frågan om hur personer som har ett spelberoende upplever sig i vardagslivet. Syftet med studien var att studera ifall personer som har ett spelberoende upplever sig avvikande i vardagslivet och i sådant fall hur. 

  15. Development of Power Electronics Based Test Platform for Characterization and Testing of Magnetocaloric Materials

    Directory of Open Access Journals (Sweden)

    Deepak Elamalayil Soman

    2015-01-01

    Full Text Available Magnetocaloric effects of various materials are getting more and more interesting for the future, as they can significantly contribute towards improving the efficiency of many energy intensive applications such as refrigeration, heating, and air conditioning. Accurate characterization of magnetocaloric effects, exhibited by various materials, is an important process for further studies and development of the suitable magnetocaloric heating and cooling solutions. The conventional test facilities have plenty of limitations, as they focus only on the thermodynamic side and use magnetic machines with moving bed of magnetocaloric material or magnet. In this work an entirely new approach for characterization of the magnetocaloric materials is presented, with the main focus on a flexible and efficient power electronic based excitation and a completely static test platform. It can generate a periodically varying magnetic field using superposition of an ac and a dc magnetic field. The scale down prototype uses a customized single phase H-bridge inverter with essential protections and an electromagnet load as actuator. The preliminary simulation and experimental results show good agreement and support the usage of the power electronic test platform for characterizing magnetocaloric materials.

  16. Testing the performance of technical trading rules in the Chinese markets based on superior predictive test

    Science.gov (United States)

    Wang, Shan; Jiang, Zhi-Qiang; Li, Sai-Ping; Zhou, Wei-Xing

    2015-12-01

    Technical trading rules have a long history of being used by practitioners in financial markets. The profitable ability and efficiency of technical trading rules are yet controversial. In this paper, we test the performance of more than seven thousand traditional technical trading rules on the Shanghai Securities Composite Index (SSCI) from May 21, 1992 through June 30, 2013 and China Securities Index 300 (CSI 300) from April 8, 2005 through June 30, 2013 to check whether an effective trading strategy could be found by using the performance measurements based on the return and Sharpe ratio. To correct for the influence of the data-snooping effect, we adopt the Superior Predictive Ability test to evaluate if there exists a trading rule that can significantly outperform the benchmark. The result shows that for SSCI, technical trading rules offer significant profitability, while for CSI 300, this ability is lost. We further partition the SSCI into two sub-series and find that the efficiency of technical trading in sub-series, which have exactly the same spanning period as that of CSI 300, is severely weakened. By testing the trading rules on both indexes with a five-year moving window, we find that during the financial bubble from 2005 to 2007, the effectiveness of technical trading rules is greatly improved. This is consistent with the predictive ability of technical trading rules which appears when the market is less efficient.

  17. Autonomous Cryogenic Load Operations: Knowledge-Based Autonomous Test Engineer

    Science.gov (United States)

    Schrading, J. Nicolas

    2013-01-01

    The Knowledge-Based Autonomous Test Engineer (KATE) program has a long history at KSC. Now a part of the Autonomous Cryogenic Load Operations (ACLO) mission, this software system has been sporadically developed over the past 20 years. Originally designed to provide health and status monitoring for a simple water-based fluid system, it was proven to be a capable autonomous test engineer for determining sources of failure in the system. As part of a new goal to provide this same anomaly-detection capability for a complicated cryogenic fluid system, software engineers, physicists, interns and KATE experts are working to upgrade the software capabilities and graphical user interface. Much progress was made during this effort to improve KATE. A display of the entire cryogenic system's graph, with nodes for components and edges for their connections, was added to the KATE software. A searching functionality was added to the new graph display, so that users could easily center their screen on specific components. The GUI was also modified so that it displayed information relevant to the new project goals. In addition, work began on adding new pneumatic and electronic subsystems into the KATE knowledge base, so that it could provide health and status monitoring for those systems. Finally, many fixes for bugs, memory leaks, and memory errors were implemented and the system was moved into a state in which it could be presented to stakeholders. Overall, the KATE system was improved and necessary additional features were added so that a presentation of the program and its functionality in the next few months would be a success.

  18. Development of a diagnostic test based on multiple continuous biomarkers with an imperfect reference test.

    Science.gov (United States)

    García Barrado, Leandro; Coart, Els; Burzykowski, Tomasz

    2016-02-20

    Ignoring the fact that the reference test used to establish the discriminative properties of a combination of diagnostic biomarkers is imperfect can lead to a biased estimate of the diagnostic accuracy of the combination. In this paper, we propose a Bayesian latent-class mixture model to select a combination of biomarkers that maximizes the area under the ROC curve (AUC), while taking into account the imperfect nature of the reference test. In particular, a method for specification of the prior for the mixture component parameters is developed that allows controlling the amount of prior information provided for the AUC. The properties of the model are evaluated by using a simulation study and an application to real data from Alzheimer's disease research. In the simulation study, 100 data sets are simulated for sample sizes ranging from 100 to 600 observations, with a varying correlation between biomarkers. The inclusion of an informative as well as a flat prior for the diagnostic accuracy of the reference test is investigated. In the real-data application, the proposed model was compared with the generally used logistic-regression model that ignores the imperfectness of the reference test. Conditional on the selected sample size and prior distributions, the simulation study results indicate satisfactory performance of the model-based estimates. In particular, the obtained average estimates for all parameters are close to the true values. For the real-data application, AUC estimates for the proposed model are substantially higher than those from the 'traditional' logistic-regression model. Copyright © 2015 John Wiley & Sons, Ltd.

  19. Generic march element based memory built-in self test

    NARCIS (Netherlands)

    Hamdioui, S.; Al-Ars, Z.; Gaydadjiev, G.N.; Van de Goor, A.J.

    2011-01-01

    Method for testing a memory under test (1) comprising a plurality of memory cells and a Memory Built-In Self-Test Engine (2) connectable to a memory under test. The MBIST engine (2) is arranged to generate appropriate addressing and read and/or write operations to the memory under test (1). The

  20. [Photoelectric parametric test system of LED based on virtual instrument].

    Science.gov (United States)

    Yang, Song-Tao; Wang, Jing; Wang, Li-Dong; Liang, Pei; Dong, Qian-Min

    2014-11-01

    The standardized measuring principle, requirements and implementations of the above parameters of LEDs were researched and analyzed in the present paper. Then a comprehensive test system involved with optics, machinery and computer was designed to accomplish data acquisition, algorithm design and interface design on virtual instrument using NI data acquisition card USB6210. And convincing results of LEDs' parameters, including peak wavelength, width of half-peak wavelength, centroid wavelength, chromaticity coordinates, purity, correlated color temperature and the forward voltage/current, were achieved with good consistency based on the measured spectrum. The system owns simple interface, reliable algorithms and stable results. Respective measurements on five kinds of color of LED result in an average error less than 3%, which show an ideal performance of the system.

  1. A self-calibrating led-based solar test platform

    DEFF Research Database (Denmark)

    Krebs, Frederik C; Sylvester-Hvid, Kristian O.; Jørgensen, Mikkel

    2011-01-01

    A compact platform for testing solar cells is presented. The light source comprises a multi-wavelength high-power LED (light emitting diode) array allowing the homogenous illumination of small laboratory solar cell devices (substrate size 50 × 25 mm) within the 390–940 nm wavelength range. The sp...... a common basis for comparing data. The use of the platform is demonstrated using a standard P3HT:PCBM polymer solar cell but is generally applicable to any solar cell technology with a spectral response in the 390–950 nm region. Copyright © 2010 John Wiley & Sons, Ltd.......A compact platform for testing solar cells is presented. The light source comprises a multi-wavelength high-power LED (light emitting diode) array allowing the homogenous illumination of small laboratory solar cell devices (substrate size 50 × 25 mm) within the 390–940 nm wavelength range......, it is possible to perform all the commonly employed measurements on the solar cell at very high speed without moving the sample. In particular, the LED-based illumination system provides an alternative to light-biased incident photon-to-current efficiency measurement to be performed which we demonstrate. Both...

  2. Computer-based test to quantify the Pulfrich stereophenomenon.

    Science.gov (United States)

    Stadelmann, Raphael; Jiang, Xiaoyi; Mojon, Daniel S

    2009-01-01

    Many eye and brain diseases may induce a spontaneous Pulfrich phenomenon (PP), a stereoillusion leading to misjudgments of objects moving in a frontoparallel plane. Since, until now, no simple PP quantification method has been available, a computer pendulum (CP) system was developed and evaluated. In 5 normal subjects, PP was induced with different neutral density filters. The resulting retardations were measured with the gold standard (a mechanical pendulum; MP), and compared to a CP, allowing the generation of interocular image phase shifts. A high correlation between MP and CP was found (r = 0.97, p 0.1 for difference with slope 1.0). A multiple linear regression showed a significant influence of the filter density and the subject tested. The type of pendulum (MP or CP) and the side on which the filter was held were nonsignificant. A CP allowing an interocular image phase shift can be used as an alternative to a MP for quantification of a PP. Thus, this principle would allow the development of software or an Internet-based test for PP quantification. However, in some subjects, the CP will overestimate and in others underestimate the real retardation measured with the MP. Copyright 2009 S. Karger AG, Basel.

  3. Papers Based Electrochemical Biosensors: From Test Strips to Paper-Based Microfluidics

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Bingwen; Du, Dan; Hua, Xin; Yu, Xiao-Ying; Lin, Yuehe

    2014-05-08

    Papers based biosensors such as lateral flow test strips and paper-based microfluidic devices (or paperfluidics) are inexpensive, rapid, flexible, and easy-to-use analytical tools. An apparent trend in their detection is to interpret sensing results from qualitative assessment to quantitative determination. Electrochemical detection plays an important role in quantification. This review focuses on electrochemical (EC) detection enabled biosensors. The first part provides detailed examples in paper test strips. The second part gives an overview of paperfluidics engaging EC detections. The outlook and recommendation of future directions of EC enabled biosensors are discussed in the end.

  4. LncRNAWiki: harnessing community knowledge in collaborative curation of human long non-coding RNAs

    KAUST Repository

    Ma, L.

    2014-11-15

    Long non-coding RNAs (lncRNAs) perform a diversity of functions in numerous important biological processes and are implicated in many human diseases. In this report we present lncRNAWiki (http://lncrna.big.ac.cn), a wiki-based platform that is open-content and publicly editable and aimed at community-based curation and collection of information on human lncRNAs. Current related databases are dependent primarily on curation by experts, making it laborious to annotate the exponentially accumulated information on lncRNAs, which inevitably requires collective efforts in community-based curation of lncRNAs. Unlike existing databases, lncRNAWiki features comprehensive integration of information on human lncRNAs obtained from multiple different resources and allows not only existing lncRNAs to be edited, updated and curated by different users but also the addition of newly identified lncRNAs by any user. It harnesses community collective knowledge in collecting, editing and annotating human lncRNAs and rewards community-curated efforts by providing explicit authorship based on quantified contributions. LncRNAWiki relies on the underling knowledge of scientific community for collective and collaborative curation of human lncRNAs and thus has the potential to serve as an up-to-date and comprehensive knowledgebase for human lncRNAs.

  5. Harnessing optical loss for unique microlaser functionality (Conference Presentation)

    Science.gov (United States)

    Feng, Liang

    2017-05-01

    Lasers, as the key driving force in the field of optics and photonics over other photonic components, are now being significantly benefited from the studies of nanophotonics and metamaterials, broadening laser physics and device applications. The properties of light are much more beyond its simple intensity and temporal characteristics. The fruitful nature of light provides a great variety of freedoms in manipulating light for modern photonic applications, including spin (polarization), chirality, angular momentum, and spin-orbit coupling. Unfortunately, all these fundamental properties and functionalities of light have not been fully exploited in micro/nano-laser systems because the conventional principles of laser design in bulk optics cannot be easily scaled down to the micro/nano scale. The capability of creating microlasers with controlled spin/orbital information and chirality in their radiations is expected to revolutionize next generation of photonic systems for computing and communication. In this talk, I will focus on our recent effort in harnessing optical losses for unique microlaser functionalities, in particular, an orbital angular momentum (OAM) microlaser that structure and twist the lasing radiation at the microscale. The effective generation of OAM lasing, especially at a micro/nano-scale, could address the growing demand for information capacity. By exploiting the emerging non-Hermitian photonics design at an exceptional point, we demonstrate a microring laser producing a single-mode OAM vortex lasing with the ability to precisely define the topological charge of the OAM mode and its polarization state. Our OAM microlaser could find applications in the next generation of integrated optoelectronic devices for optical communications.

  6. Fast Lemons and Sour Boulders: Testing Crossmodal Correspondences Using an Internet-Based Testing Methodology

    Directory of Open Access Journals (Sweden)

    Andy T. Woods

    2013-09-01

    Full Text Available According to a popular family of hypotheses, crossmodal matches between distinct features hold because they correspond to the same polarity on several conceptual dimensions (such as active–passive, good–bad, etc. that can be identified using the semantic differential technique. The main problem here resides in turning this hypothesis into testable empirical predictions. In the present study, we outline a series of plausible consequences of the hypothesis and test a variety of well-established and previously untested crossmodal correspondences by means of a novel internet-based testing methodology. The results highlight that the semantic hypothesis cannot easily explain differences in the prevalence of crossmodal associations built on the same semantic pattern (fast lemons, slow prunes, sour boulders, heavy red; furthermore, the semantic hypothesis only minimally predicts what happens when the semantic dimensions and polarities that are supposed to drive such crossmodal associations are made more salient (e.g., by adding emotional cues that ought to make the good/bad dimension more salient; finally, the semantic hypothesis does not explain why reliable matches are no longer observed once intramodal dimensions with congruent connotations are presented (e.g., visually presented shapes and colour do not appear to correspond.

  7. The Elusive Path of Brain Tissue Oxygenation and Cerebral Perfusion in Harness Hang Syncope in Mountain Climbers.

    Science.gov (United States)

    Lanfranconi, Francesca; Pollastri, Luca; Corna, Giovanni; Bartesaghi, Manuela; Novarina, Massimiliano; Ferri, Alessandra; Miserocchi, Giuseppe Andrea

    2017-10-05

    Lanfranconi, Francesca, Luca Pollastri, Giovanni Corna, Manuela Bartesaghi, Massimiliano Novarina, Alessandra Ferri, and Giuseppe Andrea Miserocchi. The elusive path of brain tissue oxygenation and cerebral perfusion in harness hang syncope in mountain climbers. High Alt Med Biol. 18:000-000, 2017. Harness hang syncope (HHS) is a risk that specifically affects wide ranges of situations requiring safety harnesses in mountains. An irreversible orthostatic stasis could lead to death if a prompt rescue is not performed. We aimed at evaluating the risk of developing HHS and at identifying the characteristics related to the pathogenesis of HHS. Forty adults (aged 39.1 [8.2] years) were enrolled in a suspension test lasting about 28.7 (11.4) minutes. We measured cardiovascular parameters, and near infrared spectroscopy (NIRS) was used to assess cerebral hypoxia by changes in the concentration of oxyhemoglobin (Δ[HbO2]) and de-oxyhemoglobin (Δ[HHb]). In the four participants who developed HHS: (1) systolic and diastolic blood pressure showed ample oscillations with a final abrupt drop (∼30 mmHg); (2) Δ[HbO2] increased after 8-12 minutes of suspension and reached a plateau before HHS; and (3) Δ[HHb] decreased with a final abrupt increase before syncope. Participants who developed HHS failed to activate cardiovascular reflexes that usually safeguard O2 availability to match the metabolic needs of the brain tissue. Since cerebral hypoxia was detected as an early phenomenon by Δ[HbO2] and Δ[HHb] changes, NIRS measurement appears to be the most important parameter to monitor the onset of HHS.

  8. Heritability and factors associated with number of harness race starts in the Spanish Trotter horse population.

    Science.gov (United States)

    Solé, M; Valera, M; Gómez, M D; Sölkner, J; Molina, A; Mészáros, G

    2017-05-01

    Longevity/durability is a relevant trait in racehorses. Genetic analysis and knowledge of factors that influence number of harness race starts would be advantageous for both horse welfare and the equine industry. To perform a genetic analysis on harness racing using number of races as a measure of longevity/durability and to identify factors associated with career length in Spanish Trotter Horses (STH). Longitudinal study. Performance data (n = 331,970) on the STH population for harness racing at national level between 1990 and 2014 were used. A grouped data model was fitted to assess factors influencing the risk of ending harness racing career and to estimate the heritability and breeding values for total number of harness races starts as an indicator of horses' longevity and durability. The model included sex, age at first race and first start earnings as time-independent effects, and the calendar year, driver, trainer, racetrack category and season of competition as time-dependent effects. Across the whole dataset, the average number of harness races horses achieved in Spain was 54.7 races, and this was associated with the horses' sex, age at first race and first start earnings, calendar year, driver, racetrack category, and season. The heritability estimated (0.17 ± 0.01) for number of harness race starts indicates that a beneficial response to direct genetic selection can be expected. Data on horses' health status were not available. Horses' total number of harness race starts is a promising tool for genetic analysis and the evaluation of racing longevity and durability. The estimated heritability provides evidence to support the application of genetic selection of total career number of races to improve longevity/durability of STH. © 2016 EVJ Ltd.

  9. Electrical failure on satellite's power harnesses due to small debris impacts

    OpenAIRE

    Hirai, Takayuki; Higashide, Masumi; Kurosaki, Hirohisa; Kawakita, Shirou; Mando, Yuki; Yamaguchi, Shota; Tanaka, Koji; 平井, 隆之; 東出, 真澄; 黒崎, 裕久; 川北, 史朗; 万戸, 雄輝; 山口, 翔太; 田中, 孝治

    2017-01-01

    Loss of satellite functions due to space debris collisions includes not only mechanical failures like breakup of satellite main bodies but also electric failures such as decrease in power supply from solar arrays and power harnesses. In particular, the past hypervelocity impact experiments suggest that sustained arcs and resulting ground faults on the power harnesses could be triggered by impacts of tiny space debris particles smaller than 1 mm which constantly impact on satellite surfaces. T...

  10. Large-area photogrammetry based testing of wind turbine blades

    Science.gov (United States)

    Poozesh, Peyman; Baqersad, Javad; Niezrecki, Christopher; Avitabile, Peter; Harvey, Eric; Yarala, Rahul

    2017-03-01

    An optically based sensing system that can measure the displacement and strain over essentially the entire area of a utility-scale blade leads to a measurement system that can significantly reduce the time and cost associated with traditional instrumentation. This paper evaluates the performance of conventional three dimensional digital image correlation (3D DIC) and three dimensional point tracking (3DPT) approaches over the surface of wind turbine blades and proposes a multi-camera measurement system using dynamic spatial data stitching. The potential advantages for the proposed approach include: (1) full-field measurement distributed over a very large area, (2) the elimination of time-consuming wiring and expensive sensors, and (3) the need for large-channel data acquisition systems. There are several challenges associated with extending the capability of a standard 3D DIC system to measure entire surface of utility scale blades to extract distributed strain, deflection, and modal parameters. This paper only tries to address some of the difficulties including: (1) assessing the accuracy of the 3D DIC system to measure full-field distributed strain and displacement over the large area, (2) understanding the geometrical constraints associated with a wind turbine testing facility (e.g. lighting, working distance, and speckle pattern size), (3) evaluating the performance of the dynamic stitching method to combine two different fields of view by extracting modal parameters from aligned point clouds, and (4) determining the feasibility of employing an output-only system identification to estimate modal parameters of a utility scale wind turbine blade from optically measured data. Within the current work, the results of an optical measurement (one stereo-vision system) performed on a large area over a 50-m utility-scale blade subjected to quasi-static and cyclic loading are presented. The blade certification and testing is typically performed using International

  11. Strategies for Ground Based Testing of Manned Lunar Surface Systems

    Science.gov (United States)

    Beyer, Jeff; Peacock, Mike; Gill, Tracy

    2009-01-01

    Integrated testing (such as Multi-Element Integrated Test (MEIT)) is critical to reducing risks and minimizing problems encountered during assembly, activation, and on-orbit operation of large, complex manned spacecraft. Provides the best implementation of "Test Like You Fly:. Planning for integrated testing needs to begin at the earliest stages of Program definition. Program leadership needs to fully understand and buy in to what integrated testing is and why it needs to be performed. As Program evolves and design and schedules mature, continually look for suitable opportunities to perform testing where enough components are together in one place at one time. The benefits to be gained are well worth the costs.

  12. Hello, world: Harnessing social media for the Rosetta mission

    Science.gov (United States)

    Baldwin, Emily; Mignone, Claudia; O'Flaherty, Karen; Homfeld, Anne-Mareike; Bauer, Markus; McCaughrean, Mark

    2015-04-01

    The European Space Agency's (ESA) comet-chasing Rosetta mission was launched in 2004, before social media became a popular tool for mainstream communication. By harnessing a range of platforms for communicating the key messages of this unprecedented mission as it reached its destination ten years later, new audiences were reached and a global impact was achieved. Rosetta-specific social media accounts - @ESA_Rosetta on Twitter, the Rosetta Mission Facebook page and the rosettamission Instagram account - were developed during 2013/14 and used alongside the traditional reporting line of the main ESA website and the Rosetta blog to build awareness about the mission. Coordinated with ESA's existing social media channels (Flickr, YouTube, G+, Twitter, Facebook and Livestream) and with the support of ESA's country desks and Rosetta partner agency accounts (including @philae2014), information could be shared in a number of European languages, ensuring a wide reach across Europe - and the world. We discuss the roles of the various social media accounts in supporting and promoting the competitions and social media campaigns that were built around the key mission milestones of 2014: waking up from deep space hibernation (January), arriving at Comet 67P/Churyumov-Gerasimenko (August) and naming the landing site for Philae ahead of the landing event in November. We discuss the different approach to each channel, such as the first person twitter accounts, the dialogue with and between blog users, and the discussions held live via G+ Hangouts with leading scientists and spacecraft operators. We compare and contrast the audiences, the interaction we had with them and how challenges were overcome. We also use the science-fiction-meets-science-fact Ambition short movie, and its "undercover" dissemination on social media, as an example of how the profile of the Rosetta mission was raised in a unique way. By using a variety of social media platforms to target different audiences with

  13. PHYTOTOXICOLOGICAL TESTS - APPLICATIONS OF FOILS BASED ON GRAPHENE (GRAPHENE OXIDE

    Directory of Open Access Journals (Sweden)

    Petra ROUPCOVÁ

    2016-12-01

    Full Text Available This paper discusses the problematics of phytotoxicity of chemicals. It mainly focuses on the phytotoxicity of nanomaterials made of graphene. It describes phytotoxicological tests performed with foils from materials belonging to the graphene family. It also describes testing the influence of plants on these films. Furthermore, the paper discusses the issues of mutual influence between plants and tested nanomaterials.

  14. Operational Based Vision Assessment Automated Vision Test Collection User Guide

    Science.gov (United States)

    2017-05-15

    repeatability to support correlation analysis. The AVT research grade tests also support interservice, international, industry, and academic partnerships...support correlation analysis. The AVT research grade tests also support interservice, international, industry, and academic partnerships. The AVT...tests are identical , only one of them is described in the example below. 18 DISTRIBUTION STATEMENT A. Approved for public release

  15. Simulated time for host-based testing with TTCN-3

    NARCIS (Netherlands)

    Blom, Stefan; Deiß, Thomas; Ioustinova, Natalia; Kontio, Ari; van de Pol, Jan Cornelis; Rennoch, Axel; Sidorova, Natalia

    2008-01-01

    Prior to testing embedded software in a target environment, it is usually tested in a host environment used for developing the software. When a system is tested in a host environment, its real-time behaviour is affected by the use of simulators, emulation and monitoring. In this paper, the authors

  16. Gold Standard Testing of Motion Based Tracking Systems

    Science.gov (United States)

    2017-03-15

    shoulder Each athlete was also wearing a Catapult 4.0 TESTING PROTOCOL The testing team mapped out 2 ‘team’ runs, and 4 different field routes...timed rest 30 seconds was led by the field testing lead, and the run was repeated back to the starting point. 88ABW-2017-1670, 17 April 2017 Figure

  17. Effects of Computer-Based Test Administrations on Test Anxiety and Performance.

    Science.gov (United States)

    Shermis, Mark D.; Lombard, Danielle

    1998-01-01

    Examines the degree to which computer and test anxiety have a predictive role in performance across three computer-administered placement tests. Subjects (72 undergraduate students) were measured with the Computer Anxiety Rating Scale, the Test Anxiety Inventory, and the Myers-Briggs Type Indicator. Results suggest that much of what is considered…

  18. Deep Unconventional Geothermal Resources: a major opportunity to harness new sources of sustainable energy

    Energy Technology Data Exchange (ETDEWEB)

    Fridleifsson, G.O.; Albertsson, A.; Stefansson, B.; Gunnlaugsson, E.; Adalsteinsson, H.

    2007-07-01

    The Iceland Deep Drilling Project (IDDP) is a long-term program to improve the efficiency and economics of geothermal energy by harnessing Deep Unconventional Geothermal Resources (DUGR). Its aim is to produce electricity from natural supercritical hydrous fluids from drillable depths. Producing supercritical fluids will require drilling wells and sampling fluids and rocks to depths of 3.5 to 5 km, and at temperatures of 450-600{sup o}C. The long-term plan is to drill and test a series of such deep boreholes in Iceland at the Krafla, the Hengill, and the Reykjanes high temperature geothermal systems. Beneath these three developed drill fields temperatures should exceed 550-650{sup o}C, and the occurrence of frequent seismic activity below 5 km, indicates that the rocks are brittle and therefore likely to be permeable. Modeling indicates that if the wellhead enthalpy is to exceed that of conventionally produced geothermal steam, the reservoir temperature must be higher than 450{sup o}C. A deep well producing 0.67 m3/sec steam ({approx}2400 m3/h) from a reservoir with a temperature significantly above 450{sup o}C could yield enough high-enthalpy steam to generate 40-50 MW of electric power. This exceeds by an order of magnitude the power typically obtained from conventional geothermal wells. (auth)

  19. Harnessing Wind Power in Moving Reference Frames with Application to Vehicles

    Science.gov (United States)

    Goushcha, Oleg; Felicissimo, Robert; Danesh-Yazdi, Amir; Andreopoulos, Yiannis

    2017-11-01

    The extraction of wind power from unique configurations embedded in moving vehicles by using micro-turbine devices has been investigated. In such moving environments, the specific power of the air motion is much greater and less intermittent than in stationary wind turbines anchored to the ground in open atmospheric conditions. In a translational frame of reference, the rate of work done by the drag force acting on the wind harnessing device due the relative motion of air should be taken into account in the overall performance evaluation through an energy balance. A device with a venting tube has been tested that connects a high-pressure stagnating flow region in the front of the vehicle with a low-pressure region at its rear. Our analysis identified two key areas to focus on for potentially significant rewards: (1) Vehicles with high energy conversion efficiency which require a high mass flow rate through the venting duct, and (2) low efficiency vehicles with wakes, which will be globally affected by the introduction of the venting duct device in a manner that reduces their drag so that there is a net gain in power generation.

  20. Organizational Benchmarks for Test Utilization Performance: An Example Based on Positivity Rates for Genetic Tests.

    Science.gov (United States)

    Rudolf, Joseph; Jackson, Brian R; Wilson, Andrew R; Smock, Kristi J; Schmidt, Robert L

    2017-04-01

    Health care organizations are under increasing pressure to deliver value by improving test utilization management. Many factors, including organizational factors, could affect utilization performance. Past research has focused on the impact of specific interventions in single organizations. The impact of organizational factors is unknown. The objective of this study is to determine whether testing patterns are subject to organizational effects, ie, are utilization patterns for individual tests correlated within organizations. Comparative analysis of ordering patterns (positivity rates for three genetic tests) across 659 organizations. Hierarchical regression was used to assess the impact of organizational factors after controlling for test-level factors (mutation prevalence) and hospital bed size. Test positivity rates were correlated within organizations. Organizations have a statistically significant impact on the positivity rate of three genetic tests.

  1. A Cost-Effectiveness Analysis of a Home-Based HIV Counselling and Testing Intervention versus the Standard (Facility Based) HIV Testing Strategy in Rural South Africa.

    Science.gov (United States)

    Tabana, Hanani; Nkonki, Lungiswa; Hongoro, Charles; Doherty, Tanya; Ekström, Anna Mia; Naik, Reshma; Zembe-Mkabile, Wanga; Jackson, Debra; Thorson, Anna

    2015-01-01

    There is growing evidence concerning the acceptability and feasibility of home-based HIV testing. However, less is known about the cost-effectiveness of the approach yet it is a critical component to guide decisions about scaling up access to HIV testing. This study examined the cost-effectiveness of a home-based HIV testing intervention in rural South Africa. Two alternatives: clinic and home-based HIV counselling and testing were compared. Costs were analysed from a provider's perspective for the period of January to December 2010. The outcome, HIV counselling and testing (HCT) uptake was obtained from the Good Start home-based HIV counselling and testing (HBHCT) cluster randomised control trial undertaken in KwaZulu-Natal province. Cost-effectiveness was estimated for a target population of 22,099 versus 23,864 people for intervention and control communities respectively. Average costs were calculated as the cost per client tested, while cost-effectiveness was calculated as the cost per additional client tested through HBHCT. Based on effectiveness of 37% in the intervention (HBHCT) arm compared to 16% in control arm, home based testing costs US$29 compared to US$38 per person for clinic HCT. The incremental cost effectiveness per client tested using HBHCT was $19. HBHCT was less costly and more effective. Home-based HCT could present a cost-effective alternative for rural 'hard to reach' populations depending on affordability by the health system, and should be considered as part of community outreach programs.

  2. A comparative evaluation of methicillin-resistant staphylococci isolated from harness racing-horses, breeding mares and riding-horses in Italy.

    Science.gov (United States)

    Mallardo, Karina; Nizza, Sandra; Fiorito, Filomena; Pagnini, Ugo; De Martino, Luisa

    2013-03-01

    To investigate the prevalence of methicillin-resistant staphylococci (MRS) which is a potencial risk factor of transmission between animals and humans in different types of horses (harness racing-horses, breeding mares and riding-horses) and to compare the antimicrobial resistance of the isolates. A total of 191 healthy horses, housed at different locations of the Campania Region (Italy), were included in the study. Nasal swab samples were collected from each nostril of the horses. The mecA gene was detected by a nested PCR technique. Antibiotic susceptibility was tested for each isolate. MRS was isolated from nasal samples of 68/191 (35.6%; 95% CI: 28.9%-42.9%) healthy horses. All isolates were coagulase-negative with the exception of two coagulase-positive MRS strains, identified as Staphylococcus aureus and Staphylococcus pseudintermedius, 2/83 (2.4%; 95% CI: 0.4%-9.2%). Interestingly, both coagulase-positive MRS isolates were from harness racing-horses. These horses also presented a significantly higher positivity for MRS (53.3%; 95% CI: 40.1%-66.1%) than the breeding mares and riding-horses groups. Antibiotic susceptibility testing showed difference between isolates due to different origins except for an almost common high resistance to aminopenicillins, such as ampicillin and amoxicillin. It can be concluded that harness racing-horses may act as a significant reservoir of MRS as compared to breeding mares and riding-horses.

  3. Toxicogenomics-based in vitro alternatives for estrogenicity testing

    NARCIS (Netherlands)

    Wang, S.

    2013-01-01

    Testing chemicals for their endocrine-disrupting potential, including interference with estrogen receptor signaling, is an important aspect to assess the safety of currently used and newly developed chemicals. The standard test for disruption of normal estrogen function is the in vivo uterotrophic

  4. TorX: Automated Model-Based Testing

    NARCIS (Netherlands)

    Tretmans, G.J.; Brinksma, Hendrik; Hartman, A.; Dussa-Ziegler, K.

    2003-01-01

    Systematic testing is very important for assessing and improving the quality of software systems. Yet, testing turns out to be expensive, laborious, time-consuming and error-prone. The Dutch research and development project Côte de Resyste worked on methods, techniques and tools for automating

  5. A Nugget-Based Test Collection Construction Paradigm

    Science.gov (United States)

    Rajput, Shahzad K.

    2012-01-01

    The problem of building test collections is central to the development of information retrieval systems such as search engines. The primary use of test collections is the evaluation of IR systems. The widely employed "Cranfield paradigm" dictates that the information relevant to a topic be encoded at the level of documents, therefore…

  6. An RSA Scheme based on Improved AKS Primality Testing Algorithm

    Directory of Open Access Journals (Sweden)

    Wu Han Wei

    2016-01-01

    Full Text Available In applied cryptography, RSA is a typical asymmetric algorithm, which is used in electronic transaction and many other security scenarios. RSA needs to generate large random primes. Currently, primality test mostly depends on probabilistic algorithms, such as the Miller-Rabin primality testing algorithm. In 2002, Agrawal et al. published the Agrawal–Kayal–Saxena (AKS primality testing algorithm, which is the first generic, polynomial, deterministic and non-hypothetical algorithm for primality test. This paper proves the necessary and sufficient condition for AKS primality test. An improved AKS algorithm is proposed using Fermat’s Little Theorem. The improved algorithm becomes an enhanced Miller-Rabin probabilistic algorithm, which can generate primes as fast as the Miller-Rabin algorithm does.

  7. Harnessing Wisdom of the Crowds Dynamics for Time-dependent Reputation and Ranking

    Science.gov (United States)

    Daly, Elizabeth M.

    The "wisdom of the crowds" is a concept used to describe the utility of harnessing group behaviour, where user opinion evolves over time and the opinion of the masses collectively demonstrates wisdom. Web 2.0 is a new medium where users are not just consumers, but are also contributors. By contributing content to the system, users become part of the network and relationships between users and content can be derived. Example applications are collaborative bookmarking networks such as dcl.icio.us and file sharing applications such as You Tube and Fliekr. These networks rely on user contributed content, described and classified using tags. The wealth of user generated content can be hard to navigate and search due to difficulties in comparing documents with similar tags and the application of traditional information retrieval scoring techniques are limited. Evaluating the time evolving interests of users may be used to derive quality of content. In this chapter, we explore a technique to rank documents based on reputation. The reputation is a combination of the number of bookmarkers, the reputation of the bookmarking user and the time dynamics of the document. Additionally, this reputation measure is extended to take into account the time-dependent, term-dependent reputation of a document. Experimental results and analysis are presented on a large collaborative IBM bookmarking network called Dogear.

  8. Harnessing CRISPR/Cas systems for programmable transcriptional and post-transcriptional regulation

    KAUST Repository

    Mahas, Ahmed

    2017-11-29

    Genome editing has enabled broad advances and novel approaches in studies of gene function and structure; now, emerging methods aim to precisely engineer post-transcriptional processes. Developing precise, efficient molecular tools to alter the transcriptome holds great promise for biotechnology and synthetic biology applications. Different approaches have been employed for targeted degradation of RNA species in eukaryotes, but they lack programmability and versatility, thereby limiting their utility for diverse applications. The CRISPR/Cas9 system has been harnessed for genome editing in many eukaryotic species and, using a catalytically inactive Cas9 variant, the CRISPR/dCas9 system has been repurposed for transcriptional regulation. Recent studies have used other CRISPR/Cas systems for targeted RNA degradation and RNA-based manipulations. For example, Cas13a, a Type VI-A endonuclease, has been identified as an RNA-guided RNA ribonuclease and used for manipulation of RNA. Here, we discuss different modalities for targeted RNA interference with an emphasis on the potential applications of CRISPR/Cas systems as programmable transcriptional regulators for broad uses, including functional biology, biotechnology, and synthetic biology applications.

  9. Harnessing rogue wave for supercontinuum generation in cascaded photonic crystal fiber.

    Science.gov (United States)

    Zhao, Saili; Yang, Hua; Zhao, Chujun; Xiao, Yuzhe

    2017-04-03

    Based on induced modulation instability, we present a numerical study on harnessing rogue wave for supercontinuum generation in cascaded photonic crystal fibers. By selecting optimum modulation frequency, we achieve supercontinuum with a great improvement on spectrum stability when long-pulse is used as the pump. In this case, rogue wave can be obtained in the first segmented photonic crystal fiber with one zero dispersion wavelength in a controllable manner. Numerical simulations show that spectral range and flatness can be regulated in an extensive range by cascading a photonic crystal fiber with two zero dispersion wavelengths. Some novel phenomena are observed in the second segmented photonic crystal fiber. When the second zero dispersion wavelength is close to the first one, rogue wave is directly translated into dispersion waves, which is conducive to the generation of smoother supercontinuum. When the second zero dispersion wavelength is far away from the first one, rogue wave is translated into the form of fundamental soliton steadily propagating in the vicinity of the second zero dispersion wavelength. Meanwhile, the corresponding red-shifted dispersion wave is generated when the phase matching condition is met, which is beneficial to the generation of wider supercontinuum. The results presented in this work provide a better application of optical rogue wave to generate flat and broadband supercontinuum in cascaded photonic crystal fibers.

  10. Harnessing biomaterials to engineer the lymph node microenvironment for immunity or tolerance.

    Science.gov (United States)

    Andorko, James I; Hess, Krystina L; Jewell, Christopher M

    2015-03-01

    Nanoparticles, microparticles, and other biomaterials are advantageous in vaccination because these materials provide opportunities to modulate specific characteristics of immune responses. This idea of "tuning" immune responses has recently been used to combat infectious diseases and cancer, and to induce tolerance during organ transplants or autoimmune disease. Lymph nodes and other secondary lymphoid organs such as the spleen play crucial roles in determining if and how these responses develop following vaccination or immunotherapy. Thus, by manipulating the local microenvironments within these immunological command centers, the nature of systemic immune response can be controlled. This review provides recent examples that harness the interactions between biomaterials and lymph nodes or other secondary lymphoid organs to generate immunity or promote tolerance. These strategies draw on mechanical properties, surface chemistry, stability, and targeting to alter the interactions of cells, signals, and vaccine components in lymph nodes. While there are still many unanswered questions surrounding how best to design biomaterial-based vaccines to promote specific structures or functions in lymph nodes, features such as controlled release and targeting will help pave the way for the next generation of vaccines and immunotherapies that generate immune responses tuned for specific applications.

  11. Developing Reading and Listening Comprehension Tests Based on the Sentence Verification Technique (SVT).

    Science.gov (United States)

    Royer, James M.

    2001-01-01

    Describes a team-based approach for creating Sentence Verification Technique (SVT) tests, a development procedure that allows teachers and other school personnel to develop comprehension tests from curriculum materials in use in their schools. Finds that if tests are based on materials that are appropriate for the population to be tested, the…

  12. Comparative feasibility of implementing rapid diagnostic test and microscopy for parasitological diagnosis of malaria in Uganda

    DEFF Research Database (Denmark)

    Batwala, Vincent; Magnussen, Pascal; Nuwaha, Fred

    2011-01-01

    and patients. Majority 23,804 (99.7%) in presumptive arm were prescribed AL. All (100%) of patients who tested positive for malaria in RDT and microscopy arms were prescribed anti-malarials. Parasitological-based diagnosis significantly reduced AL prescription in RDT arm [RR: 0.62] and microscopy arm [RR: 0...... to fully harness the benefits of parasitological confirmation of malaria, it is necessary to reduce the prescription of anti-malarials in negative patients....

  13. 49 CFR Appendix C to Part 173 - Procedure for Base-level Vibration Testing

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Procedure for Base-level Vibration Testing C... Base-level Vibration Testing Base-level vibration testing shall be conducted as follows: 1. Three... platform. 4. Immediately following the period of vibration, each package shall be removed from the platform...

  14. Development, construct validity and test-retest reliability of a field-based wheelchair mobility performance test for wheelchair basketball

    NARCIS (Netherlands)

    de Witte, Annemarie M. H.; Hoozemans, Marco J. M.; Berger, Monique A. M.; van der Slikke, Rienk M. A.; van der Woude, Lucas H. V.; Veeger, Dirkjan (H. E. J)

    2018-01-01

    The aim of this study was to develop and describe a wheelchair mobility performance test in wheelchair basketball and to assess its construct validity and reliability. To mimic mobility performance of wheelchair basketball matches in a standardised manner, a test was designed based on observation of

  15. An examination of shoulder kinematics and kinetics when using a commercial trunk harness while sheep shearing.

    Science.gov (United States)

    Gregory, Diane E; Milosavljevic, Stephan; Pal, Poonam; Callaghan, Jack P

    2008-01-01

    Sheep shearing is a very physically demanding occupation, especially on the low back, such that many commercial harnesses have been developed to help reduce the load on the back. Such harnesses have been shown to significantly reduce peak and cumulative low back loads; however, the effect that these harnesses have on the shoulders, which are also highly involved during sheep shearing, has not been previously examined. The purpose of this study was to examine the shoulder postures and cumulative shoulder moments of 12 New Zealand sheep shearers. The use of the trunk harness reduced the percentage of time spent in shoulder flexion greater than 90 degrees and the time spent in shoulder abduction greater than 45 degrees as well as reduced the cumulative net joint flexor, abductor, and adductor shoulder moments by a minimum of 21%, 14%, and 42%, respectively. Therefore, the use of a commercial trunk harness to reduce low back injury may also help to reduce the risk of shoulder injury while sheep shearing.

  16. Testing statistical hypotheses based on the density power divergence

    National Research Council Canada - National Science Library

    Basu, A; Mandal, A; Martin, N; Pardo, L

    2013-01-01

    .... It is shown that the alternative test statistics proposed herein have asymptotic limits which are described by linear combinations of Chi-square statistics. Extensive simulation results are presented to substantiate the theory developed.

  17. GVT-Based Ground Flutter Test without Wind Tunnel Project

    Data.gov (United States)

    National Aeronautics and Space Administration — ZONA Technology, Inc (ZONA) and Arizona State University (ASU) propose a R&D effort to further develop the ground flutter testing system in place of a wind...

  18. Non-Destructive Techniques Based on Eddy Current Testing

    Directory of Open Access Journals (Sweden)

    Ernesto Vázquez-Sánchez

    2011-02-01

    Full Text Available Non-destructive techniques are used widely in the metal industry in order to control the quality of materials. Eddy current testing is one of the most extensively used non-destructive techniques for inspecting electrically conductive materials at very high speeds that does not require any contact between the test piece and the sensor. This paper includes an overview of the fundamentals and main variables of eddy current testing. It also describes the state-of-the-art sensors and modern techniques such as multi-frequency and pulsed systems. Recent advances in complex models towards solving crack-sensor interaction, developments in instrumentation due to advances in electronic devices, and the evolution of data processing suggest that eddy current testing systems will be increasingly used in the future.

  19. Non-Destructive Techniques Based on Eddy Current Testing

    Science.gov (United States)

    García-Martín, Javier; Gómez-Gil, Jaime; Vázquez-Sánchez, Ernesto

    2011-01-01

    Non-destructive techniques are used widely in the metal industry in order to control the quality of materials. Eddy current testing is one of the most extensively used non-destructive techniques for inspecting electrically conductive materials at very high speeds that does not require any contact between the test piece and the sensor. This paper includes an overview of the fundamentals and main variables of eddy current testing. It also describes the state-of-the-art sensors and modern techniques such as multi-frequency and pulsed systems. Recent advances in complex models towards solving crack-sensor interaction, developments in instrumentation due to advances in electronic devices, and the evolution of data processing suggest that eddy current testing systems will be increasingly used in the future. PMID:22163754

  20. Determination of frontal offset test conditions based on crash data

    Science.gov (United States)

    1998-01-01

    This paper reports on the test procedure development : phase of the agencys Improved Frontal Protection : research program. It is anticipated that even after all cars : and light trucks have air bags for drivers and front seat : passengers there w...

  1. Non-destructive techniques based on eddy current testing.

    Science.gov (United States)

    García-Martín, Javier; Gómez-Gil, Jaime; Vázquez-Sánchez, Ernesto

    2011-01-01

    Non-destructive techniques are used widely in the metal industry in order to control the quality of materials. Eddy current testing is one of the most extensively used non-destructive techniques for inspecting electrically conductive materials at very high speeds that does not require any contact between the test piece and the sensor. This paper includes an overview of the fundamentals and main variables of eddy current testing. It also describes the state-of-the-art sensors and modern techniques such as multi-frequency and pulsed systems. Recent advances in complex models towards solving crack-sensor interaction, developments in instrumentation due to advances in electronic devices, and the evolution of data processing suggest that eddy current testing systems will be increasingly used in the future.

  2. GVT-Based Ground Flutter Test without Wind Tunnel Project

    Data.gov (United States)

    National Aeronautics and Space Administration — ZONA Technology, Inc (ZONA) and Arizona State University (ASU) propose a R&D effort to develop a ground flutter testing system without wind tunnel, called the...

  3. Testing-Based Compiler Validation for Synchronous Languages

    Science.gov (United States)

    Garoche, Pierre-Loic; Howar, Falk; Kahsai, Temesghen; Thirioux, Xavier

    2014-01-01

    In this paper we present a novel lightweight approach to validate compilers for synchronous languages. Instead of verifying a compiler for all input programs or providing a fixed suite of regression tests, we extend the compiler to generate a test-suite with high behavioral coverage and geared towards discovery of faults for every compiled artifact. We have implemented and evaluated our approach using a compiler from Lustre to C.

  4. Development of microcomputer-based mental acuity tests.

    Science.gov (United States)

    Turnage, J J; Kennedy, R S; Smith, M G; Baltzley, D R; Lane, N E

    1992-10-01

    Recent disasters have focused attention on performance problems due to the use of alcohol and controlled substances in the workplace. Environmental stressors such as thermal extremes, mixed gases, noise, motion, and vibration also have adverse effects on human performance and operator efficiency. However, the lack of a standardized, sensitive, human performance assessment battery has probably delayed the systematic study of the deleterious effects of various toxic chemicals and drugs at home and in the workplace. The collective goal of the research reported here is the development of a menu of tests embedded in a coherent package of hardware and software that may be useful in repeated-measures studies of a broad range of agents that can degrade human performance. A menu of 40 tests from the Automated Performance Test System (APTS) is described, and the series of interlocking studies supporting its development is reviewed. The APTS tests, which run on several versions of laptop portables and desktop personal computers, have been shown to be stable, reliable, and factorially rich, and to have predictive validities with holistic measures of intelligence and simulator performances. In addition, sensitivity studies have been conducted in which performance changes due to stressors, agents, and treatments were demonstrated. We believe that tests like those described here have prospective use as an adjunct to urine testing for the screening for performance loss of individuals who are granted access to workplaces and stations that impact public safety.

  5. Development, construct validity and test-retest reliability of a field-based wheelchair mobility performance test for wheelchair basketball.

    Science.gov (United States)

    de Witte, Annemarie M H; Hoozemans, Marco J M; Berger, Monique A M; van der Slikke, Rienk M A; van der Woude, Lucas H V; Veeger, Dirkjan H E J

    2018-01-01

    The aim of this study was to develop and describe a wheelchair mobility performance test in wheelchair basketball and to assess its construct validity and reliability. To mimic mobility performance of wheelchair basketball matches in a standardised manner, a test was designed based on observation of wheelchair basketball matches and expert judgement. Forty-six players performed the test to determine its validity and 23 players performed the test twice for reliability. Independent-samples t-tests were used to assess whether the times needed to complete the test were different for classifications, playing standards and sex. Intraclass correlation coefficients (ICC) were calculated to quantify reliability of performance times. Males performed better than females (P wheelchair basketball athletes. Furthermore, the described methodology of development is recommended for use in other sports to develop sport-specific tests.

  6. Cyber-Physical Energy Systems Modeling, Test Specification, and Co-Simulation Based Testing

    DEFF Research Database (Denmark)

    van der Meer, A. A.; Palensky, P.; Heussen, Kai

    2017-01-01

    The gradual deployment of intelligent and coordinated devices in the electrical power system needs careful investigation of the interactions between the various domains involved. Especially due to the coupling between ICT and power systems a holistic approach for testing and validating is require....... The presented method addresses most modeling and specification challenges in cyber-physical energy systems and is extensible for future additions such as uncertainty quantification.......The gradual deployment of intelligent and coordinated devices in the electrical power system needs careful investigation of the interactions between the various domains involved. Especially due to the coupling between ICT and power systems a holistic approach for testing and validating is required....... Taking existing (quasi-) standardised smart grid system and test specification methods as a starting point, we are developing a holistic testing and validation approach that allows a very flexible way of assessing the system level aspects by various types of experiments (including virtual, real...

  7. A computer-controlled color vision test for children based on the Cambridge Colour Test.

    Science.gov (United States)

    Goulart, Paulo R K; Bandeira, Marcio L; Tsubota, Daniela; Oiwa, Nestor N; Costa, Marcelo F; Ventura, Dora F

    2008-01-01

    The present study aimed at providing conditions for the assessment of color discrimination in children using a modified version of the Cambridge Colour Test (CCT, Cambridge Research Systems Ltd., Rochester, UK). Since the task of indicating the gap of the Landolt C used in that test proved counterintuitive and/or difficult for young children to understand, we changed the target stimulus to a patch of color approximately the size of the Landolt C gap (about 7 degrees of visual angle at 50 cm from the monitor). The modifications were performed for the CCT Trivector test which measures color discrimination for the protan, deutan and tritan confusion lines. Experiment 1 sought to evaluate the correspondence between the CCT and the child-friendly adaptation with adult subjects (n = 29) with normal color vision. Results showed good agreement between the two test versions. Experiment 2 tested the child-friendly software with children 2 to 7 years old (n = 25) using operant training techniques for establishing and maintaining the subjects' performance. Color discrimination thresholds were progressively lower as age increased within the age range tested (2 to 30 years old), and the data--including those obtained for children--fell within the range of thresholds previously obtained for adults with the CCT. The protan and deutan thresholds were consistently lower than tritan thresholds, a pattern repeatedly observed in adults tested with the CCT. The results demonstrate that the test is fit for assessment of color discrimination in young children and may be a useful tool for the establishment of color vision thresholds during development.

  8. A generic testing framework for agent-based simulation models

    OpenAIRE

    Gürcan, Önder; Dikenelli, Oguz; Bernon, Carole

    2013-01-01

    Agent-based modelling and simulation (ABMS) had an increasing attention during the last decade. However, the weak validation and verification of agent-based simulation models makes ABMS hard to trust. There is no comprehensive tool set for verification and validation of agent-based simulation models, which demonstrates that inaccuracies exist and/or reveals the existing errors in the model. Moreover, on the practical side, many ABMS frameworks are in use. In this sense, we designed and develo...

  9. Optimum methadone compliance testing: an evidence-based analysis.

    Science.gov (United States)

    2006-01-01

    The objective of this analysis was to determine the diagnostic utility of oral fluid testing collected with the Intercept oral fluid collection device. TARGET POPULATION AND CONDITION Opioids (opiates or narcotics) are a class of drugs derived from the opium poppy plant that typically relieve pain and produce a euphoric feeling. Methadone is a long-acting synthetic opioid used to treat opioid dependence and chronic pain. It prevents symptoms of opioid withdrawal, reduces opioid cravings and blocks the euphoric effects of short-acting opioids such as heroin and morphine. Opioid dependence is associated with harms including an increased risk of exposure to Human Immunodeficiency Virus and Hepatitis C as well as other health, social and psychological crises. The goal of methadone treatment is harm reduction. Treatment with methadone for opioid dependence is often a long-term therapy. The Ontario College of Physicians and Surgeons estimates that there are currently 250 physicians qualified to prescribe methadone, and 15,500 people in methadone maintenance programs across Ontario. Drug testing is a clinical tool whose purpose is to provide objective meaningful information, which will reinforce positive behavioral changes in patients and guide further treatment needs. Such information includes knowledge of whether the patient is taking their methadone as prescribed and reducing or abstaining from using opioid and other drugs of abuse use. The results of drug testing can be used with behavior modification techniques (contingency management techniques) where positive reinforcements such as increased methadone take-home privileges, sustained employment or parole are granted for drug screens negative for opioid use, and negative reinforcement including loss of these privileges for drug screens positive for opioid used. Body fluids including blood, oral fluid, often referred to as saliva, and urine may contain metabolites and the parent drug of both methadone and drugs of

  10. USING COMPUTER-BASED TESTING AS ALTERNATIVE ASSESSMENT METHOD OF STUDENT LEARNING IN DISTANCE EDUCATION

    Directory of Open Access Journals (Sweden)

    Amalia SAPRIATI

    2010-04-01

    Full Text Available This paper addresses the use of computer-based testing in distance education, based on the experience of Universitas Terbuka (UT, Indonesia. Computer-based testing has been developed at UT for reasons of meeting the specific needs of distance students as the following: Ø students’ inability to sit for the scheduled test, Ø conflicting test schedules, and Ø students’ flexibility to take examination to improve their grades. In 2004, UT initiated a pilot project in the development of system and program for computer-based testing method. Then in 2005 and 2006 tryouts in the use of computer-based testing methods were conducted in 7 Regional Offices that were considered as having sufficient supporting recourses. The results of the tryouts revealed that students were enthusiastic in taking computer-based tests and they expected that the test method would be provided by UT as alternative to the traditional paper and pencil test method. UT then implemented computer-based testing method in 6 and 12 Regional Offices in 2007 and 2008 respectively. The computer-based testing was administered in the city of the designated Regional Office and was supervised by the Regional Office staff. The development of the computer-based testing was initiated with conducting tests using computers in networked configuration. The system has been continually improved, and it currently uses devices linked to the internet or the World Wide Web. The construction of the test involves the generation and selection of the test items from the item bank collection of the UT Examination Center. Thus the combination of the selected items compromises the test specification. Currently UT has offered 250 courses involving the use of computer-based testing. Students expect that more courses are offered with computer-based testing in Regional Offices within easy access by students.

  11. National Strategies to Harness Information Technology Seeking Transformation in Singapore, Finland, the Philippines, and South Africa

    CERN Document Server

    Knight, Peter

    2012-01-01

    The ability to harness Information Communication Technologies (ICTs) is increasingly at the heart of competitiveness and sustainable growth. As countries engage in an increasingly competitive global economy, they are trying to weave ICT into their development strategies, in the same way enterprises have learned to use ICT to transform their business models and strategies. This integration offers a new path to development that is responsive to the challenges of our times.  In National Strategies to Harness Information Technology, Nagy Hanna and Peter Knight provide a framework for assessing the opportunities, challenges, and prospects for “e-transformation” and for analyzing the options and innovations adopted to manage the e-transformation process.  They ask hard questions: what does it take to harness ICT to transform an economy?  Why some countries accelerate their development journey with ICT while others fail?  How did successful countries balance the need for strategic leadership with bottom up ...

  12. Opportunities for improving pLDH-based malaria diagnostic tests

    Directory of Open Access Journals (Sweden)

    Choi Young

    2011-08-01

    Full Text Available Abstract Background Monoclonal antibodies to Plasmodium lactate dehydrogenase (pLDH have been previously used to format immunochromatographic tests for the diagnosis of malaria. Using pLDH as an antigen has several advantages as a sensitive measure of the presence of parasites within patient blood samples. However, variable results in terms of specificity and sensitivity among different commercially available diagnostic kits have been reported and it has not been clear from these studies whether the performance of an individual test is due simply to how it is engineered or whether it is due to the biochemical nature of the pLDH-antibody reaction itself. Methods A series of systematic studies to determine how various pLDH monoclonal antibodies work in combination was undertaken. Different combinations of anti-pLDH monoclonal antibodies were used in a rapid-test immunochromatographic assay format to determine parameters of sensitivity and specificity with regard to individual Plasmodium species. Results Dramatic differences were found in both species specificity and overall sensitivity depending on which antibody is used on the immunochromatographic strip and which is used on the colorimetric colloidal-gold used for visual detection. Discussion The results demonstrate the feasibility of different test formats for the detection and speciation of malarial infections. In addition, the data will enable the development of a universal rapid test algorithm that may potentially provide a cost-effective strategy to diagnose and manage patients in a wide range of clinical settings. Conclusion These data emphasize that using different anti-pLDH antibody combinations offers a tractable way to optimize immunochromatographic pLDH tests.

  13. A Web-Based Learning System for Software Test Professionals

    Science.gov (United States)

    Wang, Minhong; Jia, Haiyang; Sugumaran, V.; Ran, Weijia; Liao, Jian

    2011-01-01

    Fierce competition, globalization, and technology innovation have forced software companies to search for new ways to improve competitive advantage. Web-based learning is increasingly being used by software companies as an emergent approach for enhancing the skills of knowledge workers. However, the current practice of Web-based learning is…

  14. Thermography Used to Test Conductivity of Carbon Based Cloth

    Science.gov (United States)

    Craven, Paul

    2012-01-01

    Testing of the ability of carbon fiber to radiatively cool a heat source. The carbon fibers are attached to a heat source. The heat conducts into the fiber than along the fiber away from the heat source. The test are done in a vacuum chamber (10-5 Torr typical). The IR camera is viewing the fiber through a ZnSe window. A thermocouple (TC) in contact with the fiber is at the top right hand side of the area of interest and one is near the bottom. Thin shielding fins, seen edge on, are just above the top thermocouple.

  15. Test-based approach to cable tray support system analysis and design: Behavior and test methods

    Energy Technology Data Exchange (ETDEWEB)

    Reigles, Damon G., E-mail: dreigles@engnovex.com [engNoveX, Inc., 19C Trolley Square, Wilmington, DE 19806 (United States); Brachmann, Ingo; Johnson, William H. [Bechtel Nuclear, Security & Environmental, 12011 Sunset Hills Rd, Suite 110, Reston, VA 20190 (United States); Gürbüz, Orhan [Tobolski Watkins Engineering, Inc., 4125 Sorrento Valley Blvd, Suite B, San Diego, CA 92121 (United States)

    2016-06-15

    Highlights: • Describes dynamic response behavior of unistrut type cable tray supports. • Summarizes observations from past full-scale shake table test programs. • Outlines testing methodologies necessary to identify key system parameters. - Abstract: Nuclear power plant safety-related cable tray support systems subjected to seismic loadings were originally understood and designed to behave as linear elastic systems. This behavioral paradigm persisted until the early 1980s when, due to evolution of regulatory criteria, some as-installed systems needed to be qualified to higher seismic motions than originally designed for. This requirement prompted a more in-depth consideration of the true seismic response behavior of support systems. Several utilities initiated extensive test programs, which demonstrated that trapeze strut-type cable tray support systems exhibited inelastic and nonlinear response behaviors with plastic hinging at the connections together with high damping due to bouncing of cables in the trays. These observations were used to demonstrate and justify the seismic adequacy of the aforementioned as-installed systems. However, no formalized design methodology or criteria were ever established to facilitate use of these test data for future evaluations. This paper assimilates and reviews the various test data and conclusions for the purpose of developing a design methodology for the seismic qualification of safety-related cable tray support systems.

  16. Towards risk-based test protocols: estimating the contribution of intensive testing to the UK bovine tuberculosis problem.

    Directory of Open Access Journals (Sweden)

    Jan van Dijk

    Full Text Available Eradicating disease from livestock populations involves the balancing act of removing sufficient numbers of diseased animals without removing too many healthy individuals in the process. As ever more tests for bovine tuberculosis (BTB are carried out on the UK cattle herd, and each positive herd test triggers more testing, the question arises whether 'false positive' results contribute significantly to the measured BTB prevalence. Here, this question is explored using simple probabilistic models of test behaviour. When the screening test is applied to the average UK herd, the estimated proportion of test-associated false positive new outbreaks is highly sensitive to small fluctuations in screening test specificity. Estimations of this parameter should be updated as a priority. Once outbreaks have been confirmed in screening-test positive herds, the following rounds of intensive testing with more sensitive, albeit less specific, tests are highly likely to remove large numbers of false positive animals from herds. Despite this, it is unlikely that significantly more truly infected animals are removed. BTB test protocols should become based on quantified risk in order to prevent the needless slaughter of large numbers of healthy animals.

  17. Towards risk-based test protocols: estimating the contribution of intensive testing to the UK bovine tuberculosis problem.

    Science.gov (United States)

    van Dijk, Jan

    2013-01-01

    Eradicating disease from livestock populations involves the balancing act of removing sufficient numbers of diseased animals without removing too many healthy individuals in the process. As ever more tests for bovine tuberculosis (BTB) are carried out on the UK cattle herd, and each positive herd test triggers more testing, the question arises whether 'false positive' results contribute significantly to the measured BTB prevalence. Here, this question is explored using simple probabilistic models of test behaviour. When the screening test is applied to the average UK herd, the estimated proportion of test-associated false positive new outbreaks is highly sensitive to small fluctuations in screening test specificity. Estimations of this parameter should be updated as a priority. Once outbreaks have been confirmed in screening-test positive herds, the following rounds of intensive testing with more sensitive, albeit less specific, tests are highly likely to remove large numbers of false positive animals from herds. Despite this, it is unlikely that significantly more truly infected animals are removed. BTB test protocols should become based on quantified risk in order to prevent the needless slaughter of large numbers of healthy animals.

  18. Development of Methods to Predict the Effects of Test Media in Ground-Based Propulsion Testing

    Science.gov (United States)

    Drummond, J. Philip; Danehy, Paul M.; Gaffney, Richard L., Jr.; Parker, Peter A.; Tedder, Sarah A.; Chelliah, Harsha K.; Cutler, Andrew D.; Bivolaru, Daniel; Givi, Peyman; Hassan, Hassan A.

    2009-01-01

    This report discusses work that began in mid-2004 sponsored by the Office of the Secretary of Defense (OSD) Test & Evaluation/Science & Technology (T&E/S&T) Program. The work was undertaken to improve the state of the art of CFD capabilities for predicting the effects of the test media on the flameholding characteristics in scramjet engines. The program had several components including the development of advanced algorithms and models for simulating engine flowpaths as well as a fundamental experimental and diagnostic development effort to support the formulation and validation of the mathematical models. This report provides details of the completed work, involving the development of phenomenological models for Reynolds averaged Navier-Stokes codes, large-eddy simulation techniques and reduced-kinetics models. Experiments that provided data for the modeling efforts are also described, along with with the associated nonintrusive diagnostics used to collect the data.

  19. Using Video in Web-Based Listening Tests

    Science.gov (United States)

    Pardo-Ballester, Cristina

    2016-01-01

    With sophisticated multimedia technology, there is a renewed interest in the relationship between visual and auditory channels in assessing listening comprehension (LC). Research on the use of visuals in assessing listening has emerged with inconclusive results. Some learners perform better on tests which include visual input (Wagner, 2007) while…

  20. Genetic suppressors of the Lotus japonicus har1-1 hypernodulation phenotype

    DEFF Research Database (Denmark)

    Murray, Jeremy; Karas, Bogumil; Ross, Loretta

    2006-01-01

    symbiosis (RNS), a screen for suppressors of the L. japonicus har1-1 hypernodulation phenotype was performed. Of 150,000 M2 plants analyzed, 61 stable L. japonicus double-mutant lines were isolated. In the context of the har1-1 mutation, 26 mutant lines were unable to form RNS, whereas the remaining 35...... mutant lines carried more subtle symbiotic phenotypes, either forming white ineffective nodules or showing reduced nodulation capacity. When challenged with Glomus intraradices, 18 of the 61 suppressor lines were unable to establish a symbiosis with this arbuscular mycorrhiza fungus. Using a combined...

  1. Science har fundet løsning på CURIS-registrering

    DEFF Research Database (Denmark)

    Mørch, Frede

    2012-01-01

    Fakultetsbibliotekar Frede Mørch fortæller her om den løsning, som Science har indført for at sikre at alle forskningspublikationer bliver registreret i databasen, CURIS, uden at forskerne skal spilde tid på det.......Fakultetsbibliotekar Frede Mørch fortæller her om den løsning, som Science har indført for at sikre at alle forskningspublikationer bliver registreret i databasen, CURIS, uden at forskerne skal spilde tid på det....

  2. TerraFERMA: Harnessing Advanced Computational Libraries in Earth Science

    Science.gov (United States)

    Wilson, C. R.; Spiegelman, M.; van Keken, P.

    2012-12-01

    Many important problems in Earth sciences can be described by non-linear coupled systems of partial differential equations. These "multi-physics" problems include thermo-chemical convection in Earth and planetary interiors, interactions of fluids and magmas with the Earth's mantle and crust and coupled flow of water and ice. These problems are of interest to a large community of researchers but are complicated to model and understand. Much of this complexity stems from the nature of multi-physics where small changes in the coupling between variables or constitutive relations can lead to radical changes in behavior, which in turn affect critical computational choices such as discretizations, solvers and preconditioners. To make progress in understanding such coupled systems requires a computational framework where multi-physics problems can be described at a high-level while maintaining the flexibility to easily modify the solution algorithm. Fortunately, recent advances in computational science provide a basis for implementing such a framework. Here we present the Transparent Finite Element Rapid Model Assembler (TerraFERMA), which leverages several advanced open-source libraries for core functionality. FEniCS (fenicsproject.org) provides a high level language for describing the weak forms of coupled systems of equations, and an automatic code generator that produces finite element assembly code. PETSc (www.mcs.anl.gov/petsc) provides a wide range of scalable linear and non-linear solvers that can be composed into effective multi-physics preconditioners. SPuD (amcg.ese.ic.ac.uk/Spud) is an application neutral options system that provides both human and machine-readable interfaces based on a single xml schema. Our software integrates these libraries and provides the user with a framework for exploring multi-physics problems. A single options file fully describes the problem, including all equations, coefficients and solver options. Custom compiled applications are

  3. Test Setup for Anechoic Room based MIMO OTA Testing of LTE Terminals

    DEFF Research Database (Denmark)

    Carreño, Xavier; Fan, Wei; Nielsen, Jesper Ødum

    2013-01-01

    testing. The CTIA MIMO OTA SubGorup (MOSG) is comparing each proposed MIMO OTA technique to establish, first, an exact methodology for each technique and second, to ensure each of them offers equivalent results. This contribution focuses on the multi-probe anechoic chamber solution and summarizes...

  4. Comparison of the Clock Test and a questionnaire-based test for ...

    African Journals Online (AJOL)

    Background: Since it is projected that by 2020 seventy percent of the elderly will reside in developing countries, a reliable screening method for dementia and cognitive impairment in general in populations with diverse languages, culture, education and literacy will be needed. We sought to determine if the Clock Test, ...

  5. The Art Gallery Test: A Preliminary Comparison between Traditional Neuropsychological and Ecological VR-Based Tests

    Directory of Open Access Journals (Sweden)

    Pedro Gamito

    2017-11-01

    Full Text Available Ecological validity should be the cornerstone of any assessment of cognitive functioning. For this purpose, we have developed a preliminary study to test the Art Gallery Test (AGT as an alternative to traditional neuropsychological testing. The AGT involves three visual search subtests displayed in a virtual reality (VR art gallery, designed to assess visual attention within an ecologically valid setting. To evaluate the relation between AGT and standard neuropsychological assessment scales, data were collected on a normative sample of healthy adults (n = 30. The measures consisted of concurrent paper-and-pencil neuropsychological measures [Montreal Cognitive Assessment (MoCA, Frontal Assessment Battery (FAB, and Color Trails Test (CTT] along with the outcomes from the three subtests of the AGT. The results showed significant correlations between the AGT subtests describing different visual search exercises strategies with global and specific cognitive measures. Comparative visual search was associated with attention and cognitive flexibility (CTT; whereas visual searches involving pictograms correlated with global cognitive function (MoCA.

  6. Test-Access Planning and Test Scheduling for Embedded Core-Based System Chips

    NARCIS (Netherlands)

    Goel, Sandeep Kumar

    2005-01-01

    Advances in the semiconductor process technology enable the creation of a complete system on one single die, the so-called system chip or SOC. To reduce time-to-market for large SOCs, reuse of pre-designed and pre-veried blocks called cores is employed. Like the design style, testing of SOCs can be

  7. The Art Gallery Test: A Preliminary Comparison between Traditional Neuropsychological and Ecological VR-Based Tests

    Science.gov (United States)

    Gamito, Pedro; Oliveira, Jorge; Alghazzawi, Daniyal; Fardoun, Habib; Rosa, Pedro; Sousa, Tatiana; Maia, Ines; Morais, Diogo; Lopes, Paulo; Brito, Rodrigo

    2017-01-01

    Ecological validity should be the cornerstone of any assessment of cognitive functioning. For this purpose, we have developed a preliminary study to test the Art Gallery Test (AGT) as an alternative to traditional neuropsychological testing. The AGT involves three visual search subtests displayed in a virtual reality (VR) art gallery, designed to assess visual attention within an ecologically valid setting. To evaluate the relation between AGT and standard neuropsychological assessment scales, data were collected on a normative sample of healthy adults (n = 30). The measures consisted of concurrent paper-and-pencil neuropsychological measures [Montreal Cognitive Assessment (MoCA), Frontal Assessment Battery (FAB), and Color Trails Test (CTT)] along with the outcomes from the three subtests of the AGT. The results showed significant correlations between the AGT subtests describing different visual search exercises strategies with global and specific cognitive measures. Comparative visual search was associated with attention and cognitive flexibility (CTT); whereas visual searches involving pictograms correlated with global cognitive function (MoCA). PMID:29204128

  8. The Art Gallery Test: A Preliminary Comparison between Traditional Neuropsychological and Ecological VR-Based Tests.

    Science.gov (United States)

    Gamito, Pedro; Oliveira, Jorge; Alghazzawi, Daniyal; Fardoun, Habib; Rosa, Pedro; Sousa, Tatiana; Maia, Ines; Morais, Diogo; Lopes, Paulo; Brito, Rodrigo

    2017-01-01

    Ecological validity should be the cornerstone of any assessment of cognitive functioning. For this purpose, we have developed a preliminary study to test the Art Gallery Test (AGT) as an alternative to traditional neuropsychological testing. The AGT involves three visual search subtests displayed in a virtual reality (VR) art gallery, designed to assess visual attention within an ecologically valid setting. To evaluate the relation between AGT and standard neuropsychological assessment scales, data were collected on a normative sample of healthy adults (n = 30). The measures consisted of concurrent paper-and-pencil neuropsychological measures [Montreal Cognitive Assessment (MoCA), Frontal Assessment Battery (FAB), and Color Trails Test (CTT)] along with the outcomes from the three subtests of the AGT. The results showed significant correlations between the AGT subtests describing different visual search exercises strategies with global and specific cognitive measures. Comparative visual search was associated with attention and cognitive flexibility (CTT); whereas visual searches involving pictograms correlated with global cognitive function (MoCA).

  9. Linking Mixed-Signal Design and Test: Generation and Evaluation of Specification-Based Tests

    NARCIS (Netherlands)

    Engin, N.

    2000-01-01

    The work described in this thesis is aimed at the exploration of new methods for the integration of design and test development procedures for mixedsignal integrated circuits (IC's). Mixed-signal IC's are currently found in many electronic systems, including telecommunications, audio and video

  10. Early reading performance: a comparison of teacher-based and test-based assessments.

    Science.gov (United States)

    Kenny, D T; Chekaluk, E

    1993-04-01

    An unresolved question in early screening is whether test-based or teacher-based assessments should form the basis of the classification of children at risk of educational failure. Available structured teacher rating scales are lacking in predictive validity, and teacher predictions of students likely to experience reading difficulties have yielded disappointing true positive rates, with teachers failing to identify the majority of severely disabled readers. For this study, three educational screening instruments were developed: (a) a single teacher rating, categorizing children into three levels of reading ability (advanced, average, poor); (b) a 15-item teacher questionnaire designed to measure students' cognitive and language ability, attentional and behavioral characteristics, and academic performance; and (c) a battery of language and reading tests that are predictive of, or correlate with, reading failure. The concurrent validity of each instrument was assessed in a sample of 312 Australian schoolchildren from kindergarten, Year 1, and Year 2. Students were assessed at the end of the 1989 school year after having completed 1, 2, or 3 years of schooling. The results suggest that the nature of the skills required for success in reading changes in the first 3 years of schooling. Both teachers and tests concur more closely as children progress through the elementary years and as the risk behavior (reading) becomes more accessible to direct measurement. Carefully focused teacher rating scales may be a cost-effective means of identifying children at risk of reading failure. Improved teacher rating scales should be developed and used to assist in the early screening process.

  11. Repair mortars based on lime. Accelerated aging tests

    Directory of Open Access Journals (Sweden)

    Martínez-Ramírez, S.

    1995-06-01

    Full Text Available The behaviour under different accelerated aging tests (freeze/thaw and crystallization cycles of a new lime mortar with biocide properties destinated to monumental repair has been studied. New mortars (which have the biocide impregnated in a clay called sepiolite have a similar behaviour to lime mortars used as a reference. After the aging tests, the biocide properties of the mortars have been tried.

    Se ha estudiado el comportamiento frente a distintos ensayos de envejecimiento acelerado (ciclos de hielo/deshielo y cristalización de sales de un nuevo mortero de cal con propiedades biocidas, destinado a la reparación monumental. Se ha comprobado que los nuevos morteros (que llevan incorporado el biocida impregnado en una arcilla denominada sepiolita tienen un comportamiento muy similar a los morteros de cal utilizados como referencia. Tras los ensayos de envejecimiento se ha visto que las propiedades biocidas de los morteros se mantienen.

  12. Testing Read-Once Functions over Arbitrary Bases

    CERN Document Server

    Chistikov, Dmitry V

    2012-01-01

    A Boolean function is called read-once over a basis B if it can be expressed by a formula over B where no variable appears more than once. A checking test for a read-once function f over B depending essentially on all its variables is a set of input vectors distinguishing f from all other read-once functions of the same variables. We show that all read-once functions f over B have checking tests containing O(n^l) vectors, where n is the number of essential variables of f and l is the largest arity of functions in B. The employed technique involves reconstructing f from its l-variable projections and provides a stronger form of Kuznetsov's classic theorem on read-once representations.

  13. PSO Based Optimization of Testing and Maintenance Cost in NPPs

    Directory of Open Access Journals (Sweden)

    Qiang Chou

    2014-01-01

    Full Text Available Testing and maintenance activities of safety equipment have drawn much attention in Nuclear Power Plant (NPP to risk and cost control. The testing and maintenance activities are often implemented in compliance with the technical specification and maintenance requirements. Technical specification and maintenance-related parameters, that is, allowed outage time (AOT, maintenance period and duration, and so forth, in NPP are associated with controlling risk level and operating cost which need to be minimized. The above problems can be formulated by a constrained multiobjective optimization model, which is widely used in many other engineering problems. Particle swarm optimizations (PSOs have proved their capability to solve these kinds of problems. In this paper, we adopt PSO as an optimizer to optimize the multiobjective optimization problem by iteratively trying to improve a candidate solution with regard to a given measure of quality. Numerical results have demonstrated the efficiency of our proposed algorithm.

  14. Test Standards for Contingency Base Waste-to-Energy Technologies

    Science.gov (United States)

    2015-08-01

    followed by gas evolution from the combustion/ pyrolysis reactions which will vary over time. A very different sampling approach may be needed for batch... pyrolysis /combustion begins). 3) Potential Additional Sampling and Analysis a) Review local regulatory requirements for the test program and/or...Electric, and Alternate Fuels, Washington DC, May 2007; http://www.eia.gov/totalenergy/data/monthly/ pdf /historical/msw.pdf. 18. Xerox®, Sept 2004

  15. Life Cycle Tests on a Hollow Cathode Based Plasma Contactor

    Science.gov (United States)

    Vaughn, Jason A.; Schneider, Todd A.; Munafo, Paul (Technical Monitor)

    2001-01-01

    The propulsive Small Expendable Deployer System (ProSEDS) mission is designed to provide an on-orbit demonstration of the electrodynamic propulsion capabilities of tethers in space. The ProSEDS experiment will be a secondary payload on a Delta II unmanned expendable booster with a mission duration of 12 days. A 5-km conductive tether is attached to the Delta II second stage and collects current from the low Earth orbit (LEO) plasma, and a Hollow Cathode Plasma Contactor (HCPC) emits the collected electrons from the Delta II, completing the electrical circuit to the ambient plasma. The HCPC for the ProSEDS mission have made it necessary to turn off the HCPC once a minute throughout the entire mission. Because of the unusual operating requirements by the ProSEDS mission, an engineering development unit of the HCPC was built to demonstrate the HCPC design would start reliably for the life of the ProSEDS mission. During the life test the engineering unit cycled for over 10,000 on/off cycles without missing a single start, and during that same test the HCPC unit demonstrated the capability to emit 0 to 5 A electron emission current. The performance of the HCPC unit during this life test will be discussed.

  16. Implementing secure laptop-based testing in an undergraduate nursing program: a case study.

    Science.gov (United States)

    Tao, Jinyuan; Lorentz, B Chris; Hawes, Stacey; Rugless, Fely; Preston, Janice

    2012-07-01

    This article presents the implementation of secure laptop-based testing in an undergraduate nursing program. Details on how to design, develop, implement, and secure tests are discussed. Laptop-based testing mode is also compared with the computer-laboratory-based testing model. Five elements of the laptop-based testing model are illustrated: (1) it simulates the national board examination, (2) security is achievable, (3) it is convenient for both instructors and students, (4) it provides students hands-on practice, (5) continuous technical support is the key.

  17. The HARNESS Workbench: Unified and Adaptive Access to Diverse HPC Platforms

    Energy Technology Data Exchange (ETDEWEB)

    Sunderam, Vaidy S.

    2012-03-20

    The primary goal of the Harness WorkBench (HWB) project is to investigate innovative software environments that will help enhance the overall productivity of applications science on diverse HPC platforms. Two complementary frameworks were designed: one, a virtualized command toolkit for application building, deployment, and execution, that provides a common view across diverse HPC systems, in particular the DOE leadership computing platforms (Cray, IBM, SGI, and clusters); and two, a unified runtime environment that consolidates access to runtime services via an adaptive framework for execution-time and post processing activities. A prototype of the first was developed based on the concept of a 'system-call virtual machine' (SCVM), to enhance portability of the HPC application deployment process across heterogeneous high-end machines. The SCVM approach to portable builds is based on the insertion of toolkit-interpretable directives into original application build scripts. Modifications resulting from these directives preserve the semantics of the original build instruction flow. The execution of the build script is controlled by our toolkit that intercepts build script commands in a manner transparent to the end-user. We have applied this approach to a scientific production code (Gamess-US) on the Cray-XT5 machine. The second facet, termed Unibus, aims to facilitate provisioning and aggregation of multifaceted resources from resource providers and end-users perspectives. To achieve that, Unibus proposes a Capability Model and mediators (resource drivers) to virtualize access to diverse resources, and soft and successive conditioning to enable automatic and user-transparent resource provisioning. A proof of concept implementation has demonstrated the viability of this approach on high end machines, grid systems and computing clouds.

  18. An investigation of the statistical power of neutrality tests based on comparative and population genetic data

    DEFF Research Database (Denmark)

    Zhai, Weiwei; Nielsen, Rasmus; Slatkin, Montgomery

    2009-01-01

    In this report, we investigate the statistical power of several tests of selective neutrality based on patterns of genetic diversity within and between species. The goal is to compare tests based solely on population genetic data with tests using comparative data or a combination of comparative...

  19. Enhancing a Computer-Based Testing Environment with Optimum Item Response Time

    Science.gov (United States)

    Delen, Erhan

    2015-01-01

    As technology has become more advanced and accessible in instructional settings, there has been an upward trend in computer-based testing in the last decades. The present experimental study examines students' behaviors during computer-based testing in two different conditions and explores how these conditions affect the test results. Results…

  20. Humidifying system design of PEMFC test platform based on the mixture of dry and wet air

    Directory of Open Access Journals (Sweden)

    Tiancai Ma

    2015-01-01

    Full Text Available Based on the present humidifying system of PEMFC test platform, a novel design based on dry and wet air mixture is proposed. Key parameters are calculated, and test platform is built. Three experiments are implemented to test the performance of proposed design. Results show that the new design can meet the requirements, and realize the quick response and accurate control.

  1. Computer-Based English Language Testing in China: Present and Future

    Science.gov (United States)

    Yu, Guoxing; Zhang, Jing

    2017-01-01

    In this special issue on high-stakes English language testing in China, the two articles on computer-based testing (Jin & Yan; He & Min) highlight a number of consistent, ongoing challenges and concerns in the development and implementation of the nationwide IB-CET (Internet Based College English Test) and institutional computer-adaptive…

  2. Test-day models : breeding value estimation based on individual test-day records

    OpenAIRE

    Pool, M.H.

    2000-01-01

    The studies described in this thesis were achieved within the graduate school Wageningen Institute of Animal Science (WIAS), carried out at the Institute for Animal Science and Health (ID-Lelystad BV) at the department of Genetics and Reproduction, and financially supported by the product division NRS of CR-DELTA.

    This thesis describes choices and decisions made to develop a random regression test-day model. Studies included were performed on Dutch dairy cattle data...

  3. A new EMG frequency-based fatigue threshold test.

    Science.gov (United States)

    Hendrix, C Russell; Housh, Terry J; Johnson, Glen O; Mielke, Michelle; Camic, Clayton L; Zuniga, Jorge M; Schmidt, Richard J

    2009-06-30

    Theoretically, the critical torque (CT) and electromyographic mean power frequency fatigue threshold (EMG MPF(FT)) describe the maximal non-fatiguing isometric torque level. The purposes of this study were two-fold: (1) to determine if the mathematical model for estimating the EMG fatigue threshold (EMG(FT)) from the amplitude of the EMG signal was applicable to the frequency domain of the EMG signal to estimate a new fatigue threshold called the EMG MPF(FT); and (2) to compare the torque level derived from the CT test to that of the EMG MPF(FT) test for the vastus lateralis (VL) muscle during isometric muscle actions of the leg extensors. Nine adults (4 men and 5 women; mean+/-SD age=21.6+/-1.2 yr) performed three or four continuous, fatiguing, isometric muscle actions of the leg extensors at 30, 45, 60, and 75% of maximum voluntary isometric contraction (MVIC) to determine the time to exhaustion (T(lim)) values. The slope coefficient of the linear relationship between total isometric "work" (W(lim) in Nms=TorquexT(lim)) and T(lim) was defined as the CT. Surface EMG signals were recorded from the vastus lateralis (VL) muscle during each fatiguing isometric muscle action. The EMG MPF(FT) was defined as the y-intercept of the isometric torque versus slope coefficient (EMG MPF versus time) plot. There were no significant differences between CT (19.7+/-5.8%MVIC) and EMG MPF(FT) (21.4+/-8.7%MVIC). These findings provided indirect validation of the EMG MPF(FT) test.

  4. Designing for Learner Engagement with Computer Based Testing

    Science.gov (United States)

    Walker, Richard; Handley, Zoe

    2016-01-01

    The issues influencing student engagement with high-stakes computer-based exams were investigated, drawing on feedback from two cohorts of international MA Education students encountering this assessment method for the first time. Qualitative data from surveys and focus groups on the students' examination experience were analysed, leading to the…

  5. Testing the equality of nonparametric regression curves based on ...

    African Journals Online (AJOL)

    Abstract. In this work we propose a new methodology for the comparison of two regression functions f1 and f2 in the case of homoscedastic error structure and a fixed design. Our approach is based on the empirical Fourier coefficients of the regression functions f1 and f2 respectively. As our main results we obtain the ...

  6. Methodology of peening intensity evaluation basing on the Almen tests

    Directory of Open Access Journals (Sweden)

    A. Fedoryszyn

    2009-07-01

    Full Text Available Surfaces of casting products as well as cores and moulds require thorough cleaning and treatment. Several cleaning methods are available, depending on the type of the material, the surface’s geometry and condition, and the type of contamination. Shot peening treatment using rotor machines is a widely adopted solution and the peening performance is chiefly associated with shot peening intensity.A methodology of evaluating the peening intensity is outlined. The method uses the Almen test, widely employed when analysing the efficiency of dynamic, surface treatment methods. The evaluation method is illustrated by experimental data, process parameters and operational parameters of a shot peening machine manufactured in Poland.

  7. Pilot test and optimization of plasma based deNOx

    DEFF Research Database (Denmark)

    Stamate, Eugen; Chen, Weifeng; Michelsen, Poul

    The NOx reduction of flue gas by plasma generated ozone was investigated in pilot test experiments at two industrial power plants running on natural gas (Ringsted) and biomass (Haslev). Reduction rates higher than 95% have been achieved for a molar ratio O3:NOx of 1.56. Fourier transform infrared....... Experiments are in good agreement with numerical simulations. An optimized oxidation scheme for NOx reduction processes with time dependent combustion, such as the biomass power plants, was developed. Ozone production by micro-hollow and capillary discharges at atmospheric pressures was investigated...

  8. Model-based development and testing of advertising messages

    DEFF Research Database (Denmark)

    Bech-Larsen, Tino

    2000-01-01

    The implementation of valid and comprehensible guidelines for message development potentially enhances the effects of advertising messages and improves the possibility of measuring such effects. Moreover, such guidelines also have potential implications for the managerial communication processes...... (client-agency and intra-agency) involved in the development of advertising messages. The purpose of the study described in this paper is to compare the development and effects of two campaign proposals, with the common aim of increasing the consumption of apples among young Danes (18 to 35 years of age......-test with the target group (n=500), as well as interviews with the involved advertising agency and client2 staff....

  9. Harnessing Solar Energy Using Photosynthetic and Organic Pigments

    Science.gov (United States)

    Fitzsimons, Toby Ryan

    Fossil fuels are a finite energy resource that must be supplemented or replaced by more stable forms of electrical energy. Solar technology research strives to supplement and provide eventual replacement for fossil fuel technology. This experiment focused on the use of natural pigments as photo-sensitizers in the current generation of solar cells called dye sensitized solar cells (DSSCs). Pigments from purified chlorophyll a, chlorophyll b, chlorophyll a/b, crude spinach (Spinacia oleracea) extract, phycocyanin, and chlorophyllin were used to construct DSSCs and evaluated, along with a control containing no pigment, for solar energy conversion. The anode of the solar cells consisted of titanium dioxide (TiO2) plates soaked in pigment solutions for twenty-four hours. The plates were assembled, along with an electrolyte sandwiched between cells, and a platinum-coated counter plate that functioned as the cathode. A gasket seal was placed between the plates and held together with rubber bands. The DSSCs were each tested for a maximum power (Pmax) point and a resistor was selected that corresponded to the resistance at that point. The cells were randomly placed into a power block assembly located in an environmental chamber with lighting that provided an average of 27,590 lumens at the surface of DSSCs. With appropriate resistors in place, the cells were subjected to twelve-hour days and twelve-hour nights for ten days, and measurements were recorded every ten minutes. Data were collected to obtain values for voltage in millivolts (mV), current in microamps (microA), and power in microwatts (microW), as well as beginning and ending efficiencies in converting light to usable energy. Voltages were substantially higher during the day than at night for all pigments, except for the control, indicating that the pigments functioned as DSSCs. Hence, only daytime values were used for data analysis. Voltage during the ten-day experiment ranged from 3.99 to 274 mV; current ranged

  10. The methodology of the pedagogical tests in computer science based on the integrated model

    Directory of Open Access Journals (Sweden)

    Дмитрий Владимирович Шойтов

    2011-09-01

    Full Text Available The article deals with the creation of pedagogical tests based on the integrated model. The algorithm of the system design of test tasks in the formation of students' tests are defined by a positive test students in mastering course material.

  11. Rolling contact fatigue testing of peek based composites

    Directory of Open Access Journals (Sweden)

    Petrogalli C.

    2010-06-01

    Full Text Available Rolling contact fatigue phenomenon was investigated on unfilled PEEK and on three different PEEK composites: 10% carbon micro-fiber, graphite and PTFE filled matrix, 30% carbon micro-fiber filled matrix, 30% glass micro-fiber filled matrix. For this aim, roller-shaped specimens were machined from extruded bars of these materials and subjected to rolling contact tests at different contact pressure levels by means of a four roller machine. Contact pressure-life diagrams and wear rates were so obtained and compared, highlighting a relationship with monotonic and hardness materials properties. Microscopic observations of contact surfaces and transversal section of the specimens also allowed observing the damage mechanisms occurred in the materials tested and the effects of the filler. In particular way, deep radial cracks appeared on unfilled PEEK, while spalling and delamination phenomena where found on composites. Diffuse microcracks were found at the filler-matrix interface of the composites specimens, confirming that the fatigue life of these materials is essentially determined by the crack propagation phase, also under rolling contact loading.

  12. Mechanical Testing of Carbon Based Woven Thermal Protection Materials

    Science.gov (United States)

    Pham, John; Agrawal, Parul; Arnold, James O.; Peterson, Keith; Venkatapathy, Ethiraj

    2013-01-01

    Three Dimensional Woven thermal protection system (TPS) materials are one of the enabling technologies for mechanically deployable hypersonic decelerator systems. These materials have been shown capable of serving a dual purpose as TPS and as structural load bearing members during entry and descent operations. In order to ensure successful structural performance, it is important to characterize the mechanical properties of these materials prior to and post exposure to entry-like heating conditions. This research focuses on the changes in load bearing capacity of woven TPS materials after being subjected to arcjet simulations of entry heating. Preliminary testing of arcjet tested materials [1] has shown a mechanical degradation. However, their residual strength is significantly more than the requirements for a mission to Venus [2]. A systematic investigation at the macro and microstructural scales is reported here to explore the potential causes of this degradation. The effects of heating on the sizing (an epoxy resin coating used to reduce friction and wear during fiber handling) are discussed as one of the possible causes for the decrease in mechanical properties. This investigation also provides valuable guidelines for margin policies for future mechanically deployable entry systems.

  13. IELTS as a Literacy-Based Proficiency Test

    Directory of Open Access Journals (Sweden)

    Sugeng Purwanto

    2012-08-01

    Full Text Available This is an exploratory case study aimed at investigating whether or not International English Language Testing Systems (IELTS scores correspond with literacy levels. During the 2011-2012 academic year, 20 first semester students in the English Literature Program in the Faculty of Language and Cultural Studies (Fakultas Bahasa dan Ilmu Budaya at Universitas Stikubank (UNISBANK were randomly selected to take the IELTS. Results were matched against predetermined criteria for literacy levels (Hammond, et al. 1992 in order to classify them into the appropriate levels of literacy. Findings indicate that all students (100 percent were at the performative level of literacy with respect to their overall IELTS scores. Only 25 percent of the students on the speaking subtest and 20 percent of the students on the reading subtest managed to test at the functional level. It is therefore recommended that action research be conducted in Central Java level to upgrade the level of literacy from the performative level up to the informative level. As well, similar research may be conducted with a multi-disciplinary approach employing a correlational study between IELTS band scores with literacy levels.

  14. STRESS TESTS FOR VIDEOSTREAMING SERVICES BASED ON RTSP PROTOCOL

    Directory of Open Access Journals (Sweden)

    Gabriel Elías Chanchí Golondrino

    2015-11-01

    Full Text Available Video-streaming is a technology with major implications these days in such diverse contexts as education, health and the business sector; all of this regarding the ease it provides for remote access to live or recorded media content, allowing communication regardless of geographic location. One standard protocol that enables implementation of this technology is real time streaming protocol, or RTSP. However, since most application servers and Internet services are supported on HTTP requests, very little research has been done on generating tools for carrying out stress tests on streaming servers. This paper presents a stress measuring tool called Hermes, developed in Python, which allows calculation of response times for establishing RTSP connections to streaming servers, as well as obtaining RAM memory consumption and CPU usage rate data from these servers. Hermes was deployed in a video-streaming environment where stress testing was carried out on the LIVE555 server, using calls in the background to VLC and OpenRTSP open source clients. 

  15. Effectiveness of a computerized alert system based on re-testing intervals for limiting the inappropriateness of laboratory test requests.

    Science.gov (United States)

    Lippi, Giuseppe; Brambilla, Marco; Bonelli, Patrizia; Aloe, Rosalia; Balestrino, Antonio; Nardelli, Anna; Ceda, Gian Paolo; Fabi, Massimo

    2015-11-01

    There is consolidated evidence that the burden of inappropriate laboratory test requests is very high, up to 70%. We describe here the function of a computerized alert system linked to the order entry, designed to limit the number of potentially inappropriate laboratory test requests. A computerized alert system based on re-testing intervals and entailing the generation of pop-up alerts when preset criteria of appropriateness for 15 laboratory tests were violated was implemented in two clinical wards of the University Hospital of Parma. The effectiveness of the system for limiting potentially inappropriate tests was monitored for 6months. Overall, 765/3539 (22%) test requests violated the preset criteria of appropriateness and generated the appearance of electronic alert. After alert appearance, 591 requests were annulled (17% of total tests requested and 77% of tests alerted, respectively). The total number of test requests violating the preset criteria of inappropriateness constantly decreased over time (26% in the first three months of implementation versus 17% in the following period; prequests, generating significant economic saving and educating physicians to a more efficient use of laboratory resources. Copyright © 2015 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

  16. ADC multi-site test based on a pre-test with digital input stimulus

    NARCIS (Netherlands)

    Sheng, Xiaoqin; Metra, C.; Kerkhoff, Hans G.; Zjajo, Amir; Gronthoud, Guido

    2012-01-01

    This paper describes two novel algorithms based on the time-modulo reconstruction method intended for detection of the parametric faults in analogue-to-digital converters (ADC). In both algorithms, a pulse signal, in its slightly adapted form to allow sufficient time for converter settling, is taken

  17. Parameter testing for lattice filter based adaptive modal control systems

    Science.gov (United States)

    Sundararajan, N.; Williams, J. P.; Montgomery, R. C.

    1983-01-01

    For Large Space Structures (LSS), an adaptive control system is highly desirable. The present investigation is concerned with an 'indirect' adaptive control scheme wherein the system order, mode shapes, and modal amplitudes are estimated on-line using an identification scheme based on recursive, least-squares, lattice filters. Using the identified model parameters, a modal control law based on a pole-placement scheme with the objective of vibration suppression is employed. A method is presented for closed loop adaptive control of a flexible free-free beam. The adaptive control scheme consists of a two stage identification scheme working in series and a modal pole placement control scheme. The main conclusion from the current study is that the identified parameters cannot be directly used for controller design purposes.

  18. Testing taxpayers' cognitive abilities - Survey-based evidence

    Directory of Open Access Journals (Sweden)

    Nima Massarrat-Mashhadi

    2012-04-01

    Full Text Available Our paper assesses the accuracy of individuals' tax perceptions. Based on personal interviews, we aim to find out how tax complexity affects the capability of respondents to calculate income tax liability. Tax complexity is measured by interacting multiple tax rates, applied to one or more tax bases. Empirical results question the traditional view of taxpayers having a comprehensive understanding of taxation rules. Our findings support the view that increasing complexity affects the capability of taxpayers to accurately calculate income tax liability. For tax policy, there isalso a need to determine how taxpayers erroneously deviate in terms of extent and direction, when facing increasing tax complexity. Our research design allows us to analyze extent and possible direction of the calculation bias. Approximating an empirical distribution of erroneous calculated effective tax rates could be helpful to design a more effective income tax system.

  19. 12 CFR 652.100 - Audit of the risk-based capital stress test.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Audit of the risk-based capital stress test... AGRICULTURAL MORTGAGE CORPORATION FUNDING AND FISCAL AFFAIRS Risk-Based Capital Requirements § 652.100 Audit of the risk-based capital stress test. You must have a qualified, independent external auditor review...

  20. Life management of power plant based on structural damage testing

    Energy Technology Data Exchange (ETDEWEB)

    Tallermo, H.; Klevtsov, I. [Thermal Engineering Department of Tallinn Technical University, Tallinn (Estonia); Arras, V. [Eesti Energia, Tallinn (Estonia)

    1998-12-31

    Life management system is based on the valid nowadays in Estonian power plants regulation documentation. The system allows to estimate stress distribution in components, find computational assessment of cumulated creep damage, determine when and where it is necessary to cut off the particular number of microsamples or take replicas. Finally, the real metal condition may be assessed on the basis of metallographic specimen research and reasonable 3-R decision - run, repair, replacement - made on further component use. (orig.) 6 refs.

  1. A plan classifier based on Chi-square distribution tests

    OpenAIRE

    Iglesias Martínez, José Antonio; Ledezma Espino, Agapito Ismael; Sanchis de Miguel, María Araceli; Kaminka, Gal

    2011-01-01

    To make good decisions in a social context, humans often need to recognize the plan underlying the behavior of others, and make predictions based on this recognition. This process, when carried out by software agents or robots, is known as plan recognition, or agent modeling. Most existing techniques for plan recognition assume the availability of carefully hand-crafted plan libraries, which encode the a-priori known behavioral repertoire of the observed agents; during run-time, p...

  2. Laser-based diagnostics for propulsion and hypersonics testing

    Science.gov (United States)

    Hanson, R. K.; Chang, A. Y.; Dirosa, M. D.; Philippe, L. C.; McMillin, B. K.

    1990-06-01

    Three laser-based diagnostic methods are reviewed: two methods based on line-of-sight absorption (LOS), with application to NO and O2,and one based on planar laser-induced fluorescence (PLIF) of OH. The LOS methods utilize wavelength modulation to rapidly sweep a monochromatic laser source across one or more absorption lines; the spectral shape, amplitude, and shift of these lines lead directly to the flowfield variables of interest. LOS absorption schemes enable fast simultaneous measurements of species concentrations, temperature, velocity, density, and pressure for applications in which the flow is relatively uniform. The PLIF method utilizes a pulsed laser source with sheet illumination to produce fluorescence light in a plane which can be imaged onto an intensified solid-state camera; this fluorescence intensity distribution can effectively constitute an image of various flowfield properties. The use of PLIF methods allows simultaneous measurements at a large number of flowfield points, and it may be employed in pulsed hypersonic-flow facilities.

  3. PHARMACOGENETIC TESTING OPPORTUNITIES IN CARDIOLOGY BASED ON EXOME SEQUENCING

    Directory of Open Access Journals (Sweden)

    N. V. Shcherbakova

    2014-01-01

    Full Text Available Aim. To study what cardiac drugs currently have any comments on biomarkers and what information can be obtained by pharmacogenetic testing using data exome sequencing in patients with cardiac diseases.Material and methods. Exome sequencing in random participant of the ATEROGEN IVANOVO study and bioinformatics analysis of the data were performed. Point mutations were annotated using ANNOVAR program, as well as comparison with a number of specialized databases was done on the basis of user protocols.Results. 11 cardiac drugs and 7 genes which variants can influence cardiac drug metabolism were analyzed. According to exome sequencing of the participant we did not reveal allelic variants that require dose regime correction and careful efficacy control.Conclusion. The exome sequencing application is the next step to a wide range of personalized therapy. Future opportunities for improvement of the risk-benefit ratio in each patient are the main purpose of the collection and analysis of pharmacogenetic data.

  4. Path Scan Operational Data-Based Test Report

    Energy Technology Data Exchange (ETDEWEB)

    Hurd, Steven A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-02-13

    The TTP program is managed by DHS S&T Cyber Division and facilitates the transition of technology from the research lab to the Homeland Security Enterprise. It serves as a connection point for cyber security researchers, the Federal Government, and the private sector. Technologies targeted are those that are likely to transition successfully to the commercial market and expected to have notable impact on the cyber security of our Nation’s networks or systems. The test element of the TTP program aids in the technology transfer process and is not intended to be adversarial. Additional information on the TTP program and the iterative process used can be found in Appendix A - TTP Program Overview.

  5. Artefacts of questionnaire-based psychological testing of drivers

    Directory of Open Access Journals (Sweden)

    Anna Łuczak

    2014-06-01

    Full Text Available Background: The purpose of this article is to draw attention to a significant role of social approval variable in the qustionnairebased diagnosis of drivers' psychological aptitude. Material and Methods: Three questionnaires were used: Formal Characteristics of Behavior - Temperament Inventory (FCB-TI, Eysenck Personality Questionnaire (EPQ-R(S and Impulsiveness Questionnaire (Impulsiveness, Venturesomeness, Empathy - IVE. Three groups of drivers were analyzed: professional "without crashes" (N = 46, nonprofessional "without crashes" (N = 75, and nonprofessional "with crashes" (N = 75. Results: Nonprofessional drivers "without crashes" significantly stood up against other drivers. Their personality profile, indicating a significantly utmost perseveration, emotional reactivity, neuroticism, impulsiveness and the lowest endurance did not fit in to the requirements to be met by drivers. The driver safety profile was characteristic of professional drivers (the lowest level of perseveration, impulsiveness and neuroticism and the highest level of endurance. Similar profile occurred among nonprofessional drivers - the offenders of road crashes. Compared to the nonprofessional "without crashes" group, professional drivers and offenders of road crashes were also characterized by a significantly higher score on the Lie scale, determining the need for social approval. This is likely to result from the study procedure according to which the result of professional drivers testing had an impact on a possible continuity of their job and that of nonprofessional drivers "with crashes" decided about possible recovery of the driving license. Conclusions: The variable of social approval can be a significant artifact in the study of psychological drivers' testing and reduce the reliability of the results of questionnaire methods. Med Pr 2014;65(3:373–385

  6. Fem sociale medier har »uindskrænket ret« til at misbruge alt dit indhold

    DEFF Research Database (Denmark)

    Nielsen, Jøren Ullits Olai

    2016-01-01

    Ved du, hvor meget kontrol du har over dit indhold på Facebook, YouTube, Snapchat, Instagram og Twitter? Her giver en juraforsker dig det forkromede overblik.......Ved du, hvor meget kontrol du har over dit indhold på Facebook, YouTube, Snapchat, Instagram og Twitter? Her giver en juraforsker dig det forkromede overblik....

  7. How to Move in a Jostling Crowd The Art of Harnessing Random ...

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 1; Issue 10. How to Move in a Jostling Crowd The Art of Harnessing Random Motions. G S Ranganath. Research News Volume 1 Issue 10 October 1996 pp 84-86. Fulltext. Click here to view fulltext PDF. Permanent link:

  8. Unge er en flok egoistiske individualister, der har nok i sig selv

    DEFF Research Database (Denmark)

    Kofod, Anne

    2005-01-01

     Nutidens unge har som oftest en tvetydig identitet: På én og samme tid søger de sammen i sociale fællesskaber og gør alt for at skille sig ud som individualister.   Udgivelsesdato: 27. september...

  9. The Facebook-in-Action: Challenging, Harnessing and Enhancing Students Class Assignments and Projects

    Science.gov (United States)

    Saifudin, Adam Mohd; Yacob, Aizan; Saad, Rohaizah

    2016-01-01

    Issues of universities students harnessing and capitalizing the usage of Facebook for their own learning capabilities and effective thinking is always the focus of education scholars, in assessing the quality class assignments and projects produced by them. Therefore, Facebook is now becoming unbearable influence since the internet activation in…

  10. A Comparative Study of Harnessing Cattle - An Important Chapter in the History of European Ethnology

    Czech Academy of Sciences Publication Activity Database

    Woitsch, Jiří

    2017-01-01

    Roč. 38 (2017), s. 59-89 ISSN 1335-4116 R&D Projects: GA ČR GA15-03754S Institutional support: RVO:68378076 Keywords : harnessing cattle * European ethnology * history of ethnology Subject RIV: AC - Archeology, Anthropology, Ethnology

  11. Kvote 2 optagelse og akademiske præstationer: Hvor stor betydning har det adgangsgivende eksamenssnit?

    DEFF Research Database (Denmark)

    O'Neill, Lotte; Vonsild, Marie Cecilie; Wallstedt, Birgitta

    2013-01-01

    Kvote 2 optagelse (optagelsesprøver) til medicinstudiet har vist sig at have virket beskyttende på tidligt studiefrafald sammenlignet med kvote 1optagelse på Syddansk Universitet. Dette prospektive kohorte studie af de samme kohorter viser, at de lavere adgangsgivende karakterer i kvote 2 gruppen...

  12. Kvote 2 optagelse og akademiske præstationer: Hvor stor betydning har det adgangsgivende eksamenssnit?

    DEFF Research Database (Denmark)

    O'Neill, Lotte Dyhrberg; Vonsild, Maria Cecilie; Wallstedt, Birgitta

    2013-01-01

    Dansk abstract Kvote 2 optagelse (optagelsesprøver) til medicinstudiet har vist sig at have virket beskyttende på tidligt studiefrafald sammenlignet med kvote 1optagelse på Syddansk Universitet. Dette prospektive kohorte studie af de samme kohorter viser, at de lavere adgangsgivende karakterer i ...

  13. 42 CFR 84.1133 - Harnesses; installation and construction; minimum requirements.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Harnesses; installation and construction; minimum requirements. 84.1133 Section 84.1133 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE...

  14. Taso Mähar : maali ümber ehitatud maja / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    220-ruutmeetrise ühekorde eramu sisekujundus. Arhitekt Emil Urbel. Sisearhitekt Taso Mähar, tema kommentaarid. Köögimööbel on T. Mähari projekteeritud. Elutoas mööblifirma T&T Mang pehme mööbel, seinal Lemming Nageli maal "Punane joon all - Burn Out". Ill.: plaan, 17 värv. vaadet

  15. Secondary geochemical reactions in hydrothermal energy harnessing; Geochemische Folgereaktionen bei der hydrogeothermalen Energiegewinnung

    Energy Technology Data Exchange (ETDEWEB)

    Kuehn, M.

    1996-12-01

    This thesis is in six parts: description of geothermal energy harnessing, analytics, geochemical-thermodynamic modellings, experimental investigations, discussion of results, summary. (HW) [Deutsch] Die vorliegende Dissertationsschrift gliedert sich in 6 Teile: - Beschreibung der geothermischen Energienutzung - Analytik - geochemische-thermodynamische Modellierungen - experimentelle Untersuchungen - Diskussion der Ergebnisse - Zusammenfassung. (HW)

  16. Harnessing the power of big data: infusing the scientific method with machine learning to transform ecology

    Science.gov (United States)

    Most efforts to harness the power of big data for ecology and environmental sciences focus on data and metadata sharing, standardization, and accuracy. However, many scientists have not accepted the data deluge as an integral part of their research because the current scientific method is not scalab...

  17. Universities plan revolution in research; Four institutes will harness top brains

    CERN Multimedia

    Buie, E

    2003-01-01

    "Scotland is on the brink of revolutionising its approach to university research by creating four institutions that would harness the country's top brains to work together in specific areas. The move to create pan-academic institutes in physics, life-sciences, economics and creative arts has won the backing of the principals of every higher education institution in Scotland..." (1 page).

  18. Pressure distribution under three different types of harnesses used for guide dogs.

    Science.gov (United States)

    Peham, C; Limbeck, S; Galla, K; Bockstahler, B

    2013-12-01

    The aim of this study was to evaluate the pressure distribution under three different types of harnesses used for guide dogs (designated H1, H2 and H3). The dogs (n = 8) led a trainer through a course including a range of exercises (straight line, curve left, curve right, upstairs and downstairs). All dogs were clinically sound and showed no sign of lameness. The pressures beneath the harnesses were determined by sensor strips and related to the gait. In all harnesses, the highest pressures were found in the right sternal region (H1 2.02 ± 0.6N/cm(2); H2 1.76 ± 0.4N/cm(2); H3 1.14 ± 0.5 N/cm(2)). In all other regions, the pressures were in the range of 0-1.32 N/cm(2). The right and left sternal regions were almost constantly loaded. Contrary to previous assumptions, the back regions had minimal loading. This investigation demonstrated that there were significant differences among the harnesses. Copyright © 2013 Elsevier Ltd. All rights reserved.

  19. Harnessing the power of South-South partnerships to build capacity ...

    African Journals Online (AJOL)

    15, No. 1, June 2017. 8. Harnessing the power of South-South partnerships to build capacity for the prevention of sexual and intimate partner violence ... Sexual Violence Research Initiative, South African Medical Research Council ... programmes on IPV prevention and transforming men and masculinities show promise.

  20. Optimizing the Respiratory Pump: Harnessing Inspiratory Resistance to Treat Systemic Hypotension

    Science.gov (United States)

    2011-06-01

    error values. All the differences are statistically significant. (Adapted from Reference 14.) HARNESSING INSPIRATORY RESISTANCE TO TREAT SYSTEMIC...points represent the mean values. The error bars represent the standard error values. All the differences were statistically significant. (Adapted from...breathing Yes NA Yes Acute lung injury NA Yes Yes Penetrating chest trauma Yes Yes Yes Hypoxemia despite supplemental oxygen NA Yes Unknown

  1. Taso Mähar : "Ma ei kujunda endale ausammast" / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Taso Mähar (sünd. 1962) kodu ja ühiskondlike ruumide sisekujunduse projekteerimisest, sisekujunduses tema jaoks olulisest, klientidest, arhitektuurialastest teadmistest Eestis. T. Mäharist, omistatud preemiad. 2000. aastast töötab arhitektuuribüroos Emil Urbel. Ill.: T. Mähari värv. portree

  2. Chronological Trends in Negev Rock Art: The Har Michia Petroglyphs as a Test Case

    Directory of Open Access Journals (Sweden)

    Davida Eisenberg-Degen

    2013-10-01

    Full Text Available Negev rock art comprises a large and diverse corpus of motifs and compositions developed over the course of several millennia. As dating of specific elements is at present not possible, the rock art was analyzed statistically through the study of individual panels where internal sequences of engraving could be discerned. Examining the set of such individual sequences, larger scale reconstruction of engraving phases, sequences and patterns were recognized. Additional chronological markers, such as the presence of domestic camels or other chronologically diagnostic features, offer benchmarks for tying the general trends to more absolute frameworks. The reconstructed patterns reflect the long term history of the Negev and some of the most significant cultural and social transitions in the region are reflected visually through the rock art, notably a form of self-expression, a crucial complement to the historical sequences derived from sedentary peoples living farther north. For example the introduction of the domestic camel and its symbolic and economic significance is well evident in the rock art. Similarly, the emergence of Islam is expressed through the mark makers’ preference for "abstract" (non-figurative motifs. One motif found throughout all engraving phases, transcending the religious, political and economic structures of Negev society, is the “ibex”. Although Negev societies have all focused, to one degree or another, on sheep and goat pastoralism, these animals are rarely present in the Negev rock art and never as herds. Ibex, whose role in the diet and daily subsistence was minimal, was the most commonly depicted zoomorphic motif.

  3. NI Based System for Seu Testing of Memory Chips for Avionics

    Directory of Open Access Journals (Sweden)

    Boruzdina Anna

    2016-01-01

    Full Text Available This paper presents the results of implementation of National Instrument based system for Single Event Upset testing of memory chips into neutron generator experimental facility, which used for SEU tests for avionics purposes. Basic SEU testing algorithm with error correction and constant errors detection is presented. The issues of radiation shielding of NI based system are discussed and solved. The examples of experimental results show the applicability of the presented system for SEU memory testing under neutrons influence.

  4. Test

    DEFF Research Database (Denmark)

    Bendixen, Carsten

    2014-01-01

    Bidrag med en kortfattet, introducerende, perspektiverende og begrebsafklarende fremstilling af begrebet test i det pædagogiske univers.......Bidrag med en kortfattet, introducerende, perspektiverende og begrebsafklarende fremstilling af begrebet test i det pædagogiske univers....

  5. Harnessing Internet finance with innovative cyber credit management

    National Research Council Canada - National Science Library

    Lin, Zhangxi; Whinston, Andrew B; Fan, Shaokun

    2015-01-01

    .... Applying the exploratory research approach, we investigate major innovative Internet-based financial services and classify them into five categories, as of e-commerce, e-payment, e-money market...

  6. A new computer-based pediatric vision-screening test.

    Science.gov (United States)

    Yamada, Tomohiko; Hatt, Sarah R; Leske, David A; Moke, Pamela S; Parrucci, Nick L; Reese, J Jeffrey; Ruben, James B; Holmes, Jonathan M

    2015-04-01

    We developed and validated the Jaeb Visual Acuity Screener (JVAS), a computerized visual acuity-based screening program for children that employs a rapid, age-specific, standardized algorithm for vision screening in the medical home that is available for download at no cost. A total of 175 children aged 3 to <8 (median, 6) years were screened with the JVAS before undergoing a complete eye examination (gold standard). The JVAS presented 2 large single surround optotypes (20/100 and 20/80) and then 5 optotypes at a predetermined, age-specific normal threshold. Failure on the gold standard examination was determined using recently published referral criteria and published visual acuity norms for age. We evaluated the sensitivity and specificity of the JVAS for detecting reduced visual acuity, amblyopia, and amblyopia risk factors. JVAS pass/fail paradigms evaluated were inability to identify 3 of 4, 3 of 5, and 4 of 5 age-appropriate optotype presentations. Screening testability for the JVAS was high, at 100%. Sensitivity of the JVAS ranged from 88% to 91%, and specificity from 73% to 86%, with positive predictive value ranging from 66% to 79% and negative predictive value from 92% to 93% (ranges reflect different pass/fail paradigms). The new JVAS provides an effective and practical method for screening 3- to 7-year-olds using any Windows-based computer. Providing the JVAS free-of-charge to pediatricians and school systems would standardize currently fragmented visual acuity-based screening practices. Copyright © 2015 American Association for Pediatric Ophthalmology and Strabismus. Published by Elsevier Inc. All rights reserved.

  7. Harnessing diversity towards the reconstructing of large scale gene regulatory networks.

    Directory of Open Access Journals (Sweden)

    Takeshi Hase

    Full Text Available Elucidating gene regulatory network (GRN from large scale experimental data remains a central challenge in systems biology. Recently, numerous techniques, particularly consensus driven approaches combining different algorithms, have become a potentially promising strategy to infer accurate GRNs. Here, we develop a novel consensus inference algorithm, TopkNet that can integrate multiple algorithms to infer GRNs. Comprehensive performance benchmarking on a cloud computing framework demonstrated that (i a simple strategy to combine many algorithms does not always lead to performance improvement compared to the cost of consensus and (ii TopkNet integrating only high-performance algorithms provide significant performance improvement compared to the best individual algorithms and community prediction. These results suggest that a priori determination of high-performance algorithms is a key to reconstruct an unknown regulatory network. Similarity among gene-expression datasets can be useful to determine potential optimal algorithms for reconstruction of unknown regulatory networks, i.e., if expression-data associated with known regulatory network is similar to that with unknown regulatory network, optimal algorithms determined for the known regulatory network can be repurposed to infer the unknown regulatory network. Based on this observation, we developed a quantitative measure of similarity among gene-expression datasets and demonstrated that, if similarity between the two expression datasets is high, TopkNet integrating algorithms that are optimal for known dataset perform well on the unknown dataset. The consensus framework, TopkNet, together with the similarity measure proposed in this study provides a powerful strategy towards harnessing the wisdom of the crowds in reconstruction of unknown regulatory networks.

  8. Harnessing diversity towards the reconstructing of large scale gene regulatory networks.

    Science.gov (United States)

    Hase, Takeshi; Ghosh, Samik; Yamanaka, Ryota; Kitano, Hiroaki

    2013-01-01

    Elucidating gene regulatory network (GRN) from large scale experimental data remains a central challenge in systems biology. Recently, numerous techniques, particularly consensus driven approaches combining different algorithms, have become a potentially promising strategy to infer accurate GRNs. Here, we develop a novel consensus inference algorithm, TopkNet that can integrate multiple algorithms to infer GRNs. Comprehensive performance benchmarking on a cloud computing framework demonstrated that (i) a simple strategy to combine many algorithms does not always lead to performance improvement compared to the cost of consensus and (ii) TopkNet integrating only high-performance algorithms provide significant performance improvement compared to the best individual algorithms and community prediction. These results suggest that a priori determination of high-performance algorithms is a key to reconstruct an unknown regulatory network. Similarity among gene-expression datasets can be useful to determine potential optimal algorithms for reconstruction of unknown regulatory networks, i.e., if expression-data associated with known regulatory network is similar to that with unknown regulatory network, optimal algorithms determined for the known regulatory network can be repurposed to infer the unknown regulatory network. Based on this observation, we developed a quantitative measure of similarity among gene-expression datasets and demonstrated that, if similarity between the two expression datasets is high, TopkNet integrating algorithms that are optimal for known dataset perform well on the unknown dataset. The consensus framework, TopkNet, together with the similarity measure proposed in this study provides a powerful strategy towards harnessing the wisdom of the crowds in reconstruction of unknown regulatory networks.

  9. Mood As Cumulative Expectation Mismatch: A Test of Theory Based on Data from Non-verbal Cognitive Bias Tests

    Directory of Open Access Journals (Sweden)

    Camille M. C. Raoult

    2017-12-01

    Full Text Available Affective states are known to influence behavior and cognitive processes. To assess mood (moderately long-term affective states, the cognitive judgment bias test was developed and has been widely used in various animal species. However, little is known about how mood changes, how mood can be experimentally manipulated, and how mood then feeds back into cognitive judgment. A recent theory argues that mood reflects the cumulative impact of differences between obtained outcomes and expectations. Here expectations refer to an established context. Situations in which an established context fails to match an outcome are then perceived as mismatches of expectation and outcome. We take advantage of the large number of studies published on non-verbal cognitive bias tests in recent years (95 studies with a total of 162 independent tests to test whether cumulative mismatch could indeed have led to the observed mood changes. Based on a criteria list, we assessed whether mismatch had occurred with the experimental procedure used to induce mood (mood induction mismatch, or in the context of the non-verbal cognitive bias procedure (testing mismatch. For the mood induction mismatch, we scored the mismatch between the subjects’ potential expectations and the manipulations conducted for inducing mood whereas, for the testing mismatch, we scored mismatches that may have occurred during the actual testing. We then investigated whether these two types of mismatch can predict the actual outcome of the cognitive bias study. The present evaluation shows that mood induction mismatch cannot well predict the success of a cognitive bias test. On the other hand, testing mismatch can modulate or even inverse the expected outcome. We think, cognitive bias studies should more specifically aim at creating expectation mismatch while inducing mood states to test the cumulative mismatch theory more properly. Furthermore, testing mismatch should be avoided as much as possible

  10. Test and Score Data Summary for TOEFL[R] Internet-Based and Paper-Based Tests. January 2008-December 2008 Test Data

    Science.gov (United States)

    Educational Testing Service, 2008

    2008-01-01

    The Test of English as a Foreign Language[TM], better known as TOEFL[R], is designed to measure the English-language proficiency of people whose native language is not English. TOEFL scores are accepted by more than 6,000 colleges, universities, and licensing agencies in 130 countries. The test is also used by governments, and scholarship and…

  11. Flexural Test of Fly Ash based Geopolimer Concrete Beams

    Directory of Open Access Journals (Sweden)

    Nindyawati

    2017-01-01

    Full Text Available Fly ash is a by-product from the coal industry, which is widely available in Indonesia. Fly ash contains quite high silicate and alumina. Silica and alumina reacts with alkaline solution to produce alumina silicate gel which binds the aggregate to produce geopolymer concrete. Geopolymer concrete is introduced as an environmental concrete with high compressive strength. The use of geopolymer concrete beams is a solution to reduce the effects of greenhouse gases. This research uses experimental designs. The data are obtained from the testing of 4 pieces of reinforced geopolymer concrete beams and reinforced ordinary concrete beams with a / d of 1.11 and 2.24. The results are obtained from the maximum load that can be accepted by the beam. The results of this study are: (1 Geopolymer concrete cylinder has 26.78% higher compressive strength than ordinary concrete cylinders (2 Ordinary concrete beams can withstand 34.8% load higher compared to the geopolymer concrete beam (3 Reinforced ordinary concrete beams experience bending shear collapse while reinforced geopolymer concrete beam experience pure bending collapse.

  12. A Range-Based Test for the Parametric Form of the Volatility in Diffusion Models

    DEFF Research Database (Denmark)

    Podolskij, Mark; Ziggel, Daniel

    statistic. Under rather weak assumptions on the drift and volatility we prove weak convergence of the test statistic to a centered mixed Gaussian distribution. As a consequence we obtain a test, which is consistent for any fixed alternative. We also provide a test for neighborhood hypotheses. Moreover, we...... present a parametric bootstrap procedure which provides a better approximation of the distribution of the test statistic. Finally, it is demonstrated by means of Monte Carlo study that the range-based test is more powerful than the return-based test when comparing at the same sampling frequency....

  13. Improving adherence to safe prescription guidelines for Dapsone: harnessing an enhanced electronic medical records system and a team approach.

    Science.gov (United States)

    Neoh, Ching Yin; Tian, Elizabeth A L; Choi, Cindy; Leong, Hui Hui; Tan, Audrey W H; Chan, Roy K W

    2012-03-01

    Dapsone is a commonly prescribed medication in dermatological practice. Its use is associated with a broad spectrum of adverse effects. Careful selection and monitoring of patients on dapsone are paramount in the prevention and early recognition of adverse effects. We designed a risk-management program for dapsone at National Skin Centre, Singapore, enhancing an existing electronic medical records system and harnessing a team approach involving the nurses. This includes the performance of key laboratory tests before and after starting dapsone, ensuring adequate counseling before starting dapsone and screening for adverse effects using a questionnaire every visit. This system of dapsone prescription efficiently improved the adherence to safe prescription and monitoring guidelines. Average adherence rates for key safety parameters improved from 61.4% pre-implementation to 95.3% at six months and were sustained at 12 months at 91.3%. Percentage of follow-up cases in which all three key monitoring parameters were fulfilled increased from 9.5% to 79.6% (p=0.0001) after 12months. The percentage of new patients in which all four key monitoring parameters were met increased from 50% to 80%. It was not statistically significant possibly because of small patient numbers. This project has also translated into enhanced patient safety with dapsone dosages adjusted in 17 patients who experienced mild adverse effects. No severe adverse effects to dapsone were observed in the 12-month period. This example of risk management for dapsone may serve as a model for institutions looking at harnessing information technology and a team approach for safer prescription of high-alert medications. © 2012 The International Society of Dermatology.

  14. Testing an Algae-Based Air-Regeneration System

    Science.gov (United States)

    Nienow, James

    1998-01-01

    The potential of an air-regeneration system based on the growth of unicellular algae on the surface of porous ceramic tubes was evaluated. The system is fairly robust with respect to environmental conditions and is capable of maintaining algal cultures for up to 365 days. Under standard conditions (50-66 micro mol/sq mm s (PPF), 450 micro mol mol of CO2), mature tubes can remove CO2 at a rate of up to 90 micro mol/sq m min. Under these conditions, approximately 200 square meters of area would be required for each member of the crew. However, the rate of uptake increases with both photon flux and CO2 concentration in accordance with Michaelis-Menton dynamics. An extrapolation to conditions of saturating light and carbon dioxide indicates that the area required can be reduced by a factor of at least 2.5.

  15. A General Asymptotic Framework for Distribution-Free Graph-Based Two-Sample Tests

    OpenAIRE

    Bhattacharya, Bhaswar B.

    2015-01-01

    Testing equality of two multivariate distributions is a classical problem for which many non-parametric tests have been proposed over the years. Most of the popular two-sample tests, which are asymptotically distribution-free, are based either on geometric graphs constructed using inter-point distances between the observations (multivariate generalizations of the Wald-Wolfowitz's runs test) or on multivariate data-depth (generalizations of the Mann-Whitney rank test). This paper introduces a ...

  16. Safety impact of an integrated crash warning system based on field test data.

    Science.gov (United States)

    2011-06-13

    This paper provides the results of an analysis : conducted to assess the safety impact of an integrated : vehicle-based crash warning system based on : naturalistic driving data collected from a field : operational test. The system incorporates four ...

  17. The Memory Stack: New Technologies Harness Talking for Writing.

    Science.gov (United States)

    Gannon, Maureen T.

    In this paper, an elementary school teacher describes her experiences with the Memory Stack--a HyperCard based tool that can accommodate a voice recording, a graphic image, and a written text on the same card--which she designed to help her second and third grade students integrate their oral language fluency into the process of learning how to…

  18. Fejlagtig kritik har afsporet miljødebatten

    DEFF Research Database (Denmark)

    Nørgaard, Jørgen

    2008-01-01

    a sustainable and decent life. The critique of L.t.G turns out to be based on claims with no substance in the report. On the contrary, so far nothing has indicated that the report was in any sense fundamentally wrong. Unfortunately the erroneous critique has managed to convince many that the report was wrong...

  19. Combining the P300-complex trial-based concealed information test and the reaction time-based autobiographical implicit association test in concealed memory detection.

    Science.gov (United States)

    Hu, Xiaoqing; Rosenfeld, J Peter

    2012-08-01

    Despite the P300-concealed information test's validity in detecting concealed memory when it is conducted immediately after the mock crime, whether the P300-CIT's detection efficiency is moderated by time delay remains unknown. Here, we conducted a mock crime study in which guilty participants were tested immediately after the mock crime or 1 month later. An innocent group was also tested. Assuming that the autobiographical Implicit Association Test (aIAT) and the P300-CIT rely on nonoverlapping mechanisms for memory detection, participants were tested using both the P300-CIT and the reaction time (RT)-based aIAT. Results suggested that the sensitivity of both tests remains even after the 1-month delay. The indicators from the RT-aIAT and P300-CIT were uncorrelated, thus combining P300-CIT and aIAT data further increased the efficiency of memory detection. Copyright © 2012 Society for Psychophysiological Research.

  20. New Insights into Nanoindentation-Based Adhesion Testing

    Science.gov (United States)

    Kleinbichler, A.; Pfeifenberger, M. J.; Zechner, J.; Moody, N. R.; Bahr, D. F.; Cordill, M. J.

    2017-11-01

    Nanoindentation, or instrumented indentation, is a versatile technique that is most often used to measure the elastic modulus and hardness of thin film systems. It can also be employed to measure thin film adhesion energies by producing well-defined areas of delamination. When combined with the proper mechanics-based model and characterization of the failing interfaces, nanoindentation-induced delamination is a powerful tool to quantify interfacial fracture. This article highlights new improvements to the technique that build off the work of Marshall and Evans in the 1980s. Indentation-induced delamination in systems with brittle films or substrates can be a balance between causing delamination and causing through-thickness or bulk fracture. Focused ion beam cross-sectioning and confocal laser scanning microscopy were used to characterize failing interfaces, additional fracture events were observed in the load-displacement curves, and the adhesion energy was determined using not only symmetric, ideally shaped buckles, but also irregular-shaped and half-delaminated buckles.

  1. Design of a testing strategy using non-animal based test methods: lessons learnt from the ACuteTox project.

    Science.gov (United States)

    Kopp-Schneider, Annette; Prieto, Pilar; Kinsner-Ovaskainen, Agnieszka; Stanzel, Sven

    2013-06-01

    In the framework of toxicology, a testing strategy can be viewed as a series of steps which are taken to come to a final prediction about a characteristic of a compound under study. The testing strategy is performed as a single-step procedure, usually called a test battery, using simultaneously all information collected on different endpoints, or as tiered approach in which a decision tree is followed. Design of a testing strategy involves statistical considerations, such as the development of a statistical prediction model. During the EU FP6 ACuteTox project, several prediction models were proposed on the basis of statistical classification algorithms which we illustrate here. The final choice of testing strategies was not based on statistical considerations alone. However, without thorough statistical evaluations a testing strategy cannot be identified. We present here a number of observations made from the statistical viewpoint which relate to the development of testing strategies. The points we make were derived from problems we had to deal with during the evaluation of this large research project. A central issue during the development of a prediction model is the danger of overfitting. Procedures are presented to deal with this challenge. Copyright © 2012 Elsevier Ltd. All rights reserved.

  2. Do sediment type and test durations affect results of laboratory-based, accelerated testing studies of permeable pavement clogging?

    Science.gov (United States)

    Nichols, Peter W B; White, Richard; Lucke, Terry

    2015-04-01

    Previous studies have attempted to quantify the clogging processes of Permeable Interlocking Concrete Pavers (PICPs) using accelerated testing methods. However, the results have been variable. This study investigated the effects that three different sediment types (natural and silica), and different simulated rainfall intensities, and testing durations had on the observed clogging processes (and measured surface infiltration rates) of laboratory-based, accelerated PICP testing studies. Results showed that accelerated simulated laboratory testing results are highly dependent on the type, and size of sediment used in the experiments. For example, when using real stormwater sediment up to 1.18 mm in size, the results showed that neither testing duration, nor stormwater application rate had any significant effect on PICP clogging. However, the study clearly showed that shorter testing durations generally increased clogging and reduced the surface infiltration rates of the models when artificial silica sediment was used. Longer testing durations also generally increased clogging of the models when using fine sediment (life of these increasingly common stormwater best management practices. Copyright © 2015 Elsevier B.V. All rights reserved.

  3. Toward a superconducting quantum computer. Harnessing macroscopic quantum coherence.

    Science.gov (United States)

    Tsai, Jaw-Shen

    2010-01-01

    Intensive research on the construction of superconducting quantum computers has produced numerous important achievements. The quantum bit (qubit), based on the Josephson junction, is at the heart of this research. This macroscopic system has the ability to control quantum coherence. This article reviews the current state of quantum computing as well as its history, and discusses its future. Although progress has been rapid, the field remains beset with unsolved issues, and there are still many new research opportunities open to physicists and engineers.

  4. Harnessing Apoptotic Cell Clearance to Treat Autoimmune Arthritis

    OpenAIRE

    Philippe Saas; Francis Bonnefoy; Eric Toussirot; Sylvain Perruche

    2017-01-01

    Early-stage apoptotic cells possess immunomodulatory properties. Proper apoptotic cell clearance during homeostasis has been shown to limit subsequent immune responses. Based on these observations, early-stage apoptotic cell infusion has been used to prevent unwanted inflammatory responses in different experimental models of autoimmune diseases or transplantation. Moreover, this approach has been shown to be feasible without any toxicity in patients undergoing allogeneic hematopoietic cell tr...

  5. Harnessing ontology and machine learning for RSO classification.

    Science.gov (United States)

    Liu, Bin; Yao, Li; Han, Dapeng

    2016-01-01

    Classification is an important part of resident space objects (RSOs) identification, which is a main focus of space situational awareness. Owing to the absence of some features caused by the limited and uncertain observations, RSO classification remains a difficult task. In this paper, an ontology for RSO classification named OntoStar is built upon domain knowledge and machine learning rules. Then data describing RSO are represented by OntoStar. A demo shows how an RSO is classified based on OntoStar. It is also shown in the demo that traceable and comprehensible reasons for the classification can be given, hence the classification can be checked and validated. Experiments on WEKA show that ontology-based classification gains a relatively high accuracy and precision for classifying RSOs. When classifying RSOs with imperfect data, ontology-based classification keeps its performances, showing evident advantages over classical machine learning classifiers who either have increases of 5 % at least in FP rate or have decreases of 5 % at least in indexes such as accuracy, precision and recall.

  6. Microbes at Surface-Air Interfaces: The Metabolic Harnessing of Relative Humidity,Surface Hygroscopicity and Oligotrophy or Resilience

    Directory of Open Access Journals (Sweden)

    Wendy Stone

    2016-09-01

    Full Text Available The human environment is predominantly not aqueous, and microbes are ubiquitous at the surface-air interfaces with which we interact. Yet microbial studies at surface-air interfaces are largely survival-oriented, whilst microbial metabolism has overwhelmingly been investigated from the perspective of liquid saturation. This study explored microbial survival and metabolism under desiccation, particularly the influence of relative humidity, surface hygroscopicity, and nutrient availability on the interchange between these two types of behavior. The combination of a hygroscopic matrix (i.e., clay or 4,000 MW polyethylene glycol and high relative humidity (RH resulted in persistent measurable microbial metabolism during desiccation. In contrast, no microbial metabolism was detected at (a hygroscopic interfaces at low RH, and (b less hygroscopic interfaces (ie., sand and plastic/glass at high or low RH. Cell survival was conversely inhibited at high RH and promoted at low RH, irrespective of surface hygroscopicity. Based on this demonstration of metabolic persistence and survival inhibition at high relative humidity, it was proposed that biofilm metabolic rates might inversely influence whole-biofilm resilience, with ‘resilience’ defined in this study as a biofilm’s capacity to recover from desiccation. The concept of whole-biofilm resilience being promoted by oligotrophy was supported in desiccation-tolerant Arthrobacter spp. biofilms, but not in desiccation-sensitive Pseudomonas aeruginosa biofilms. The ability of microbes to interact with surfaces to harness water vapor during desiccation was demonstrated, and potentially to harness oligotrophy (the most ubiquitous natural condition facing microbes for adaptation to desiccation.

  7. Using Fuzzy Logic Techniques for Assertion-Based Software Testing Metrics

    Directory of Open Access Journals (Sweden)

    Ali M. Alakeel

    2015-01-01

    Full Text Available Software testing is a very labor intensive and costly task. Therefore, many software testing techniques to automate the process of software testing have been reported in the literature. Assertion-Based automated software testing has been shown to be effective in detecting program faults as compared to traditional black-box and white-box software testing methods. However, the applicability of this approach in the presence of large numbers of assertions may be very costly. Therefore, software developers need assistance while making decision to apply Assertion-Based testing in order for them to get the benefits of this approach at an acceptable level of costs. In this paper, we present an Assertion-Based testing metrics technique that is based on fuzzy logic. The main goal of the proposed technique is to enhance the performance of Assertion-Based software testing in the presence of large numbers of assertions. To evaluate the proposed technique, an experimental study was performed in which the proposed technique is applied on programs with assertions. The result of this experiment shows that the effectiveness and performance of Assertion-Based software testing have improved when applying the proposed testing metrics technique.

  8. Validation of a web-based version of the asthma control test and childhood asthma control test.

    Science.gov (United States)

    Koolen, B B; Pijnenburg, M W H; Brackel, H J L; Landstra, A M; van den Berg, N J; Merkus, P J F M; Hop, W C J; Vaessen-Verberne, A A P H

    2011-10-01

    Recent guidelines focus on adjusting asthma treatment to the level of asthma control. The availability of a web-based asthma control questionnaire offers the possibility to assess asthma control without the need of outpatient clinic visits. The aim of this study was to evaluate the agreement between web-based and paper-based versions of the Asthma Control Test (ACT) and Childhood Asthma Control Test (C-ACT), short-term reproducibility and satisfaction with both versions. One hundred seventy-three children with stable asthma and a normal lung function were randomized to fill in a web-based or paper-based version of the C-ACT (4-11 years) or ACT (12-18 years). According to a cross-over design, they completed the opposite version after 1 week. Reproducibility was evaluated by repeating the 2nd version (web- or paper-based) 7 days later. Eighty-eight children filled in the C-ACT, 68 children filled in the ACT. Intraclass Correlation Coefficient (ICC) for web-based versus paper-based C-ACT was 0.81 (95% confidence interval [95% CI] 0.72-0.87). For ACT this was 0.84 (95% CI 0.76-0.90). For web-based and paper-based C-ACT the reproducibility ICC was 0.82 (95% CI 0.67-0.90) and 0.75 (95% CI 0.59-0.85), respectively. The reproducibility ICC of the ACT for web- and paper-based versions was 0.93 (95% CI 0.87-0.97) and 0.77 (95% CI 0.59-0.88), respectively. Eighty-six percent of patients preferred the web-based version. The web-based version of the C-ACT and ACT is reproducible and comparable with the paper-based version in assessing asthma control. Most children and their parents prefer the web-based version. Copyright © 2011 Wiley-Liss, Inc.

  9. Technological innovations in mental healthcare: harnessing the digital revolution.

    Science.gov (United States)

    Hollis, Chris; Morriss, Richard; Martin, Jennifer; Amani, Sarah; Cotton, Rebecca; Denis, Mike; Lewis, Shôn

    2015-04-01

    Digital technology has the potential to transform mental healthcare by connecting patients, services and health data in new ways. Digital online and mobile applications can offer patients greater access to information and services and enhance clinical management and early intervention through access to real-time patient data. However, substantial gaps exist in the evidence base underlying these technologies. Greater patient and clinician involvement is needed to evaluate digital technologies and ensure they target unmet needs, maintain public trust and improve clinical outcomes. Royal College of Psychiatrists.

  10. Flammability Testing of Fabrics Treated with Oil-Based Shear Thickening Fluids

    Science.gov (United States)

    2014-05-01

    rather than the Kevlar fibers , burned during the experiment. 13 (a...thickening fluid (STF) are evaluated under flammability testing. The tested fabrics include a woven cotton-nylon blend, a woven Kevlar textile, and a...hybrid ultrahigh molecular weight polyethylene (UHMWPE) – Kevlar felt. The oil-based STF is a colloid of silica nanoparticles in a paraffin oil. Test

  11. T3, a Combinator-based Random Testing Tool for Java: Benchmarking

    NARCIS (Netherlands)

    Prasetya, I.S.W.B.

    2014-01-01

    T3 is the next generation of the light weight automated testing tool T2 for Java. In the heart T3 is still a random testing tool; but it now comes with some new features: pair-wise testing, concurrent generators, and a combinator-based approach ala QuickCheck. This paper presents the result of

  12. A Comment on Early Student Blunders on Computer-Based Adaptive Tests

    Science.gov (United States)

    Green, Bert F.

    2011-01-01

    This article refutes a recent claim that computer-based tests produce biased scores for very proficient test takers who make mistakes on one or two initial items and that the "bias" can be reduced by using a four-parameter IRT model. Because the same effect occurs with pattern scores on nonadaptive tests, the effect results from IRT scoring, not…

  13. Multi-Criteria Adaptation in a Personalized Multimedia Testing Tool Based on Semantic Technologies

    Science.gov (United States)

    Lazarinis, Fotis; Green, Steve; Pearson, Elaine

    2011-01-01

    In this article, we present the characteristics and the design of a modular personalized multimedia testing tool based fully on XML learning specifications. Personalization is based on the characteristics of the individual learners, thus the testing paths are tailored to their needs and goals. The system maintains learner profiles rich in content…

  14. A Mixture Rasch Model-Based Computerized Adaptive Test for Latent Class Identification

    Science.gov (United States)

    Jiao, Hong; Macready, George; Liu, Junhui; Cho, Youngmi

    2012-01-01

    This study explored a computerized adaptive test delivery algorithm for latent class identification based on the mixture Rasch model. Four item selection methods based on the Kullback-Leibler (KL) information were proposed and compared with the reversed and the adaptive KL information under simulated testing conditions. When item separation was…

  15. A multivariate family-based association test using generalized estimating equations : FBAT-GEE

    NARCIS (Netherlands)

    Lange, C; Silverman, SK; Xu, [No Value; Weiss, ST; Laird, NM

    In this paper we propose a multivariate extension of family-based association tests based on generalized estimating equations. The test can be applied to multiple phenotypes and to phenotypic data obtained in longitudinal studies without making any distributional assumptions for the phenotypic

  16. A Comparison of Teacher and Test-Based Assessment for Spanish Primary and Secondary Students

    Science.gov (United States)

    Marcenaro-Gutierrez, Oscar; Vignoles, Anna

    2015-01-01

    Background: Education systems rely on both teacher and test-based assessments. Where these assessments are used for summative purposes particularly, it is important to understand why, and for which groups of students, teachers' assessments may produce different results from test-based assessments. Purpose: This paper assesses whether the…

  17. T-UPPAAL: Online Model-based Testing of Real-Time Systems

    DEFF Research Database (Denmark)

    Mikucionis, Marius; Larsen, Kim Guldstrand; Nielsen, Brian

    2004-01-01

    The goal of testing is to gain confidence in a physical computer based system by means of executing it. More than one third of typical project resources is spent on testing embedded and real-time systems, but still it remains ad-hoc, based on heuristics, and error-prone. Therefore systematic...

  18. Unit-based functional IDDT testing for aging degradation monitoring in a VLIW processor

    NARCIS (Netherlands)

    Zhao, Yong; Kerkhoff, Hans G.

    2015-01-01

    In this paper, functional unit-based IDDT testing has been applied for a 90nm VLIW processor to monitor its aging degradation. This technique can provide health data for reliability evaluation as used in e.g. prognostic software for lifetime prediction. The test-program development based on the

  19. A Range-Based Test for the Parametric Form of the Volatility in Diffusion Models

    DEFF Research Database (Denmark)

    Podolskij, Mark; Ziggel, Daniel

    statistic. Under rather weak assumptions on the drift and volatility we prove weak convergence of the test statistic to a centered mixed Gaussian distribution. As a consequence we obtain a test, which is consistent for any fixed alternative. Moreover, we present a parametric bootstrap procedure which...... provides a better approximation of the distribution of the test statistic. Finally, it is demonstrated by means of Monte Carlo study that the range-based test is more powerful than the return-based test when comparing at the same sampling frequency....

  20. Criterion-related validity of field-based muscular fitness tests in youth.

    Science.gov (United States)

    Artero, E G; España-Romero, V; Castro-Piñero, J; Ruiz, J; Jiménez-Pavón, D; Aparicio, V; Gatto-Cardia, M; Baena, P; Vicente-Rodríguez, G; Castillo, M J; Ortega, F B

    2012-06-01

    The purpose of the present study was to analyze the association between isokinetic strength and field-based muscular fitness tests in youth. One hundred twenty-six adolescents (14.4±1.7 y) participated in the study. Upper and lower body isokinetic strength were measured at preset angular velocities of 90 º/s and 60 º/s, respectively. Muscular fitness was also assessed by means of field-based tests: handgrip strength, bent and extended arm hang tests, standing long jump, squat jump, countermovement jump and Abalakov jump. Height, weight and skinfold thickness were used to estimate body composition. All field-based tests were significantly associated with isokinetic peak torque and power (Pvalid field-based muscular fitness tests when compared to isokinetic strength. These tests can be useful to assess muscular fitness in young people when laboratory methods are not feasible.

  1. Improving the Learning Experience by Harnessing Digital Technology

    Directory of Open Access Journals (Sweden)

    Panagiota Koulouvari R.

    2012-02-01

    Full Text Available The paper will explore how a social media based E-learning 2.0 solution for formal learning (social IS can be implemented, focusing on the technology acceptance process. The paper aims to increase the knowledge on how the acceptance regarding social media based E-learning 2.0 information systems for formal learning can be increased and how the acceptance affects the social learning experience. To achieve this, the paper relies on both a qualitative and quantitative approach and is primarily inductive. The paper concludes that the acceptance cannot be seen as a linear process, as is common practice. Instead, one should see the process of acceptance as interlinked with the experience and external variables in a continuous process that can either ‘spiral’ upwards or downwards. Furthermore, the paper identifies the problem of innovation resistance. The paper then analyzes information gathered from industry experts, practitioners and a live case to find how one can improve acceptance and thereby the social learning experience. Once these variables have been identified the paper presents strategic advice. The paper ends by a discussion of the results, both regarding the impact and contrast to previous research as well as highlighting areas for further research

  2. Design of a sentence identification test with pictures (TIS-F based on the pediatric speech intelligibility test

    Directory of Open Access Journals (Sweden)

    Fernanda Freitas Vellozo

    Full Text Available ABSTRACT Purposes: to design a sentence identification test with pictures for adults (Teste de Identificação de Sentenças com Figuras (TIS-F as an alternative for evaluation of auditory figure-background ability for verbal sounds, based on the Pediatric Speech Intelligibility Test and also for assessment of unskillful individuals who cannot accomplish other tests with higher levels of difficulty and greater demands. Methods: the Adobe Illustrator software was used and the image vectorization technique applied for figures creation. The sentences and the competitive message were audio-recorded in a sound treated room by a female announcer, using the software - REAPER - FM Digital Audio Workstation. Results: the TIS-F consisted of a 32 x 45 cm card, containing 10 figures, each one measuring 12 x 12 cm; one compact disc containing a track with the test calibration tone and seven test tracks, each one containing ten sentences and a competitive message and a specific protocol. Conclusion: the TIS-F is composed of a compact disc with dual-channel recording, with seven tracks containing ten sentences and the competitive story, one card containing ten pictures and a labeling protocol for all presentations and S/N in use, as well as the established normality values.

  3. Harnessing case isolation and ring vaccination to control Ebola.

    Directory of Open Access Journals (Sweden)

    Chad Wells

    2015-05-01

    Full Text Available As a devastating Ebola outbreak in West Africa continues, non-pharmaceutical control measures including contact tracing, quarantine, and case isolation are being implemented. In addition, public health agencies are scaling up efforts to test and deploy candidate vaccines. Given the experimental nature and limited initial supplies of vaccines, a mass vaccination campaign might not be feasible. However, ring vaccination of likely case contacts could provide an effective alternative in distributing the vaccine. To evaluate ring vaccination as a strategy for eliminating Ebola, we developed a pair approximation model of Ebola transmission, parameterized by confirmed incidence data from June 2014 to January 2015 in Liberia and Sierra Leone. Our results suggest that if a combined intervention of case isolation and ring vaccination had been initiated in the early fall of 2014, up to an additional 126 cases in Liberia and 560 cases in Sierra Leone could have been averted beyond case isolation alone. The marginal benefit of ring vaccination is predicted to be greatest in settings where there are more contacts per individual, greater clustering among individuals, when contact tracing has low efficacy or vaccination confers post-exposure protection. In such settings, ring vaccination can avert up to an additional 8% of Ebola cases. Accordingly, ring vaccination is predicted to offer a moderately beneficial supplement to ongoing non-pharmaceutical Ebola control efforts.

  4. Harnessing Photovoice for tuberculosis advocacy in Karachi, Pakistan.

    Science.gov (United States)

    Mohammed, Shama; Sajun, Sana Zehra; Khan, Faisal S

    2015-06-01

    In Pakistan, despite publically available free testing and treatment throughout the country, there were an estimated 58,000 deaths due to tuberculosis in 2010. Understanding the experiences of people affected by TB is essential in addressing barriers to effective treatment. The Indus Hospital used Photovoice to understand the experiences of people affected by TB in Karachi. Two hundred and thirty photographs and stories were collected from 55 people affected by TB. Five major themes and 12 sub-themes emerged from the data: the physical aspects of TB (weakness and the side effects of the medication), the social aspects of TB (loneliness, stigma, and the fear/guilt of infecting family members), the socio-economic aspects of TB (financial difficulties/poverty and poor living conditions), supportive factors during treatment (support from family and friends, support from welfare organizations, prayer, visiting peaceful places), and recovery (happiness about getting better). The photographs, stories, and a Call for Action were shared at a Gallery event with patients, practitioners, and policy-makers. This study provides a look at the complexities surrounding TB and emphasizes the need for holistic interventions for TB that address all aspects of the disease, including its social determinants. It also highlights the potential of Photovoice as an effective means to bring much-needed attention to this disease. © The Author (2013). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  5. On distance-based permutation tests for between-group comparisons.

    Science.gov (United States)

    Reiss, Philip T; Stevens, M Henry H; Shehzad, Zarrar; Petkova, Eva; Milham, Michael P

    2010-06-01

    Permutation tests based on distances among multivariate observations have found many applications in the biological sciences. Two major testing frameworks of this kind are multiresponse permutation procedures and pseudo-F tests arising from a distance-based extension of multivariate analysis of variance. In this article, we derive conditions under which these two frameworks are equivalent. The methods and equivalence results are illustrated by reanalyzing an ecological data set and by a novel application to functional magnetic resonance imaging data.

  6. Experimental Research on Vibration Fatigue of CFRP and Its Influence Factors Based on Vibration Testing

    OpenAIRE

    Fan, Zhengwei; Jiang, Yu; Zhang, Shufeng; Chen, Xun

    2017-01-01

    A new research method based on vibration testing for the vibration fatigue of FRP was proposed in this paper. Through the testing on a closed-loop controlled vibration fatigue test system, the vibration fatigue phenomenon of typical carbon-fiber-reinforced plastic (CFRP) cantilevered laminate specimens was carefully studied. Moreover, a method based on the frequency response function was proposed to monitor the fatigue damage accumulation of specimens. On the basis of that, the influence fact...

  7. Beyond bibliometrics harnessing multidimensional indicators of scholarly impact

    CERN Document Server

    Sugimoto, Cassidy R

    2014-01-01

    Bibliometrics has moved well beyond the mere tracking of bibliographic citations. The web enables new ways to measure scholarly productivity and impact, making available tools and data that can reveal patterns of intellectual activity and impact that were previously invisible: mentions, acknowledgments, endorsements, downloads, recommendations, blog posts, tweets. This book describes recent theoretical and practical advances in metrics-based research, examining a variety of alternative metrics -- or "altmetrics" -- while also considering the ethical and cultural consequences of relying on metrics to assess the quality of scholarship. Once the domain of information scientists and mathematicians, bibliometrics is now a fast-growing, multidisciplinary field that ranges from webometrics to scientometrics to influmetrics. The contributors to Beyond Bibliometrics discuss the changing environment of scholarly publishing, the effects of open access and Web 2.0 on genres of discourse, novel analytic methods, and the e...

  8. Harnessing the Interaction Continuum for Subtle Assisted Living

    Science.gov (United States)

    García-Herranz, Manuel; Olivera, Fernando; Haya, Pablo; Alamán, Xavier

    2012-01-01

    People interact with each other in many levels of attention, intention and meaning. This Interaction Continuum is used daily to deal with different contexts, adapting the interaction to communication needs and available resources. Nevertheless, computer-supported interaction has mainly focused on the most direct, explicit and intrusive types of human to human Interaction such as phone calls, emails, or video conferences. This paper presents the results of exploring and exploiting the potentials of undemanding interaction mechanisms, paying special attention to subtle communication and background interaction. As we argue the benefits of this type of interaction for people with special needs, we present a theoretical framework to define it and propose a proof of concept based on Augmented Objects and a color codification mechanism. Finally, we evaluate and analyze the strengths and limitations of such approach with people with cognitive disabilities. PMID:23012573

  9. Harnessing context sensing to develop a mobile intervention for depression.

    Science.gov (United States)

    Burns, Michelle Nicole; Begale, Mark; Duffecy, Jennifer; Gergle, Darren; Karr, Chris J; Giangrande, Emily; Mohr, David C

    2011-08-12

    Mobile phone sensors can be used to develop context-aware systems that automatically detect when patients require assistance. Mobile phones can also provide ecological momentary interventions that deliver tailored assistance during problematic situations. However, such approaches have not yet been used to treat major depressive disorder. The purpose of this study was to investigate the technical feasibility, functional reliability, and patient satisfaction with Mobilyze!, a mobile phone- and Internet-based intervention including ecological momentary intervention and context sensing. We developed a mobile phone application and supporting architecture, in which machine learning models (ie, learners) predicted patients' mood, emotions, cognitive/motivational states, activities, environmental context, and social context based on at least 38 concurrent phone sensor values (eg, global positioning system, ambient light, recent calls). The website included feedback graphs illustrating correlations between patients' self-reported states, as well as didactics and tools teaching patients behavioral activation concepts. Brief telephone calls and emails with a clinician were used to promote adherence. We enrolled 8 adults with major depressive disorder in a single-arm pilot study to receive Mobilyze! and complete clinical assessments for 8 weeks. Promising accuracy rates (60% to 91%) were achieved by learners predicting categorical contextual states (eg, location). For states rated on scales (eg, mood), predictive capability was poor. Participants were satisfied with the phone application and improved significantly on self-reported depressive symptoms (beta(week) = -.82, P interview measures of depressive symptoms (beta(week) = -.81, P technical functionality, data mining, and software development process are discussed. Clinicaltrials.gov NCT01107041; http://clinicaltrials.gov/ct2/show/NCT01107041 (Archived by WebCite at http://www.webcitation.org/60CVjPH0n).

  10. The Estimation of Knowledge Solidity Based on the Comparative Analysis of Different Test Results

    Directory of Open Access Journals (Sweden)

    Y. K. Khenner

    2012-01-01

    Full Text Available At present, the testing techniques of knowledge estimation are widely spread in educational system. However, this method is seriously criticized including its application to the Unified State Examinations. The research is aimed at studying the limitations of testing techniques. The authors recommend a new way of knowledge solid- ity estimation bases on the comparative results analysis of various kinds of tests. While testing the large group of students, the authors found out that the results of the closed and open tests substantially differ. The comparative analysis demonstrates that the open tests assessment of the knowledge solidity is more adequate than that of the closed ones. As the research is only based on a single experiment, the authors recommend using this method further, substantiating the findings concerning the differences in tests results, and analyzing the advantages and disadvantages of the tests in question. 

  11. Using Built-In Domain-Specific Modeling Support to Guide Model-Based Test Generation

    Directory of Open Access Journals (Sweden)

    Teemu Kanstrén

    2012-02-01

    Full Text Available We present a model-based testing approach to support automated test generation with domain-specific concepts. This includes a language expert who is an expert at building test models and domain experts who are experts in the domain of the system under test. First, we provide a framework to support the language expert in building test models using a full (Java programming language with the help of simple but powerful modeling elements of the framework. Second, based on the model built with this framework, the toolset automatically forms a domain-specific modeling language that can be used to further constrain and guide test generation from these models by a domain expert. This makes it possible to generate a large set of test cases covering the full model, chosen (constrained parts of the model, or manually define specific test cases on top of the model while using concepts familiar to the domain experts.

  12. Harnessing information technology to innovate in primary care.

    Science.gov (United States)

    Jiwa, Moyez; McManus, Alexander; Dadich, Ann; White, James; Rieck, Alison; Razmi, Shohreh

    2013-01-01

    The health sector's capacity to meet the changing needs of patients is being questioned. This has significant implications for patients, carers, health services and those who hold the public purse. It is therefore important to bolster its capacity to serve a greater proportion of people in need of health care, opportunities for which might be facilitated by information technology (IT). To identify strategies to bolster the capacity of the primary care sector to deploy and innovate with IT. Three discussion groups comprising clinicians, regulatory agents, innovators and academics from each Australian state. Themes discussed included: (1) health problems that can be readily solved by IT, (2) clinician engagement with IT, (3) experiences with IT implementation, (4) engagement with hard-to-reach groups, and (5) social media use. Although participants were aware of the issues surrounding the use of IT, including limited evidence and reduced data integrity, they were equally aware of the opportunities afforded by IT. With appropriate support, they indicated that IT could help to innovate and reinvigorate the primary care sector. This could be demonstrated via research, initiatives that improve governance arrangements (within and beyond the primary care sector), programmes that enhance care delivery and consumer empowerment initiatives. Clinicians are rarely included as part of teams developing innovations, and technology is not always tailored for clinical practice or tested on clinical outcomes. Technical and access issues continue to hamper dissemination of innovation. The need for leadership in developing IT healthcare solutions remains paramount, with the organisation best able to negotiate with the key stakeholders at the helm.

  13. Harnessing the power of the new SMP cluster architecture

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, S E; Cohen, R H; Curtis, B C; Dannevik, W P; Dimits, A M; Dinge, D; Eliason, D E; Hodsons, S; Jacobs, M; Mirin, A A; Porter, D H; Ruwart, T; Synne, I; Winkler, K; Woodward, P R

    1999-06-16

    In 1993, members of our team collaborated with Silicon Graphics to perform the first full-scale demonstration of the computational power of the SMP cluster supercomputer architecture. That demonstration involved the simulation of homogeneous, compressible turbulence on a uniform grid of a billion cells, using our PPM gas dynamics code. This computation was embarrassingly parallel, the ideal test case, and it achieved only 4.9 Gflop/s performance, slightly over half that achievable by this application on the most expensive supercomputers of that day. After four to five solid days of computation, when the prototype machine had to be dismantled, the simulation was only about 20% completed. Nevertheless, this computation gave us important new insights into compressible turbulence and also into a powerful new mode of cost-effective, commercially sustainable supercomputing [S]. In the intervening 6 years, the SMP cluster architecture has become a fundamental strategy for several large supercomputer centers in the US, including the DOE's ASCI centers at Los Alamos National Laboratory and at the Lawrence Livermore National Laboratory and the NSF's center NCSA at the University of Illinois. This SMP cluster architecture now underlies product offerings at the high-end of performance from SGI, IBM, and HP, among others. Nevertheless, despite many successes, it is our opinion that the computational science community is only now beginning to exploit the full promise of these new computing platforms. In this paper, we will briefly discuss two key architectural issues, vector computing and the flat multiprocessor architecture, which continue to drive spirited discussions among computational scientists, and then we will describe the hierarchical shared memory programming paradigm that we feel is best suited to the creative use of SMP cluster systems. Finally, we will give examples of recent large-scale simulations carried out by our team on these kinds of systems and

  14. Construction and Testing of a 21 GHz Ceramic Based Power Extractor

    CERN Document Server

    Newsham, D; Carron, G; Döbert, Steffen; Gai, W; Konecny, R; Liu, W; Smirnov, A Yu; Thorndahl, L; Wilson, Ian H; Wuensch, Walter; Yu, D

    2003-01-01

    A ceramic based power extractor [1] operating at 21 GHz was built by DULY Research Inc. and tested at CTF2, the CERN Linear Collider (CLIC) Test Facility. The structure includes a ceramic extractor section, a 2-output-port, circular-to-rectangular waveguide coupler, and a 3-port rectangular waveguide combiner that provides for a single output waveguide. Results of cold tests and full beam tests are presented and compared with theoretical and numerical models.

  15. Evidence-based guidelines for universal counselling and offering of HIV testing in pregnancy in Canada

    OpenAIRE

    Samson, L; King, S.

    1998-01-01

    OBJECTIVE: To provide Canadian health care workers with evidence-based guidelines for universal counselling about HIV testing and the offering of such testing to all pregnant women. OPTIONS: Universal counselling and offering of HIV testing to all pregnant women versus targeted testing of only pregnant women at high risk for HIV infection. Antiretroviral treatment protocols for HIV-positive mothers and their infants are discussed as the intervention to reduce mother-to-child transmission rate...

  16. Development of hybrid electric vehicle powertrain test system based on virtue instrument

    Science.gov (United States)

    Xu, Yanmin; Guo, Konghui; Chen, Liming

    2017-05-01

    Hybrid powertrain has become the standard configuration of some automobile models. The test system of hybrid vehicle powertrain was developed based on virtual instrument, using electric dynamometer to simulate the work of engines, to test the motor and control unit of the powertrain. The test conditions include starting, acceleration, and deceleration. The results show that the test system can simulate the working conditions of the hybrid electric vehicle powertrain under various conditions.

  17. Design of Accelerated Reliability Test for CNC Motorized Spindle Based on Vibration Signal

    Directory of Open Access Journals (Sweden)

    Chen Chao

    2016-01-01

    Full Text Available Motorized spindle is the key functional component of CNC machining centers which is a mechatronics system with long life and high reliability. The reliability test cycle of motorized spindle is too long and infeasible. This paper proposes a new accelerated test for reliability evaluation of motorized spindle. By field reliability test, authors collect and calculate the load data including rotational speed, cutting force and torque. Load spectrum distribution law is analyzed. And authors design a test platform to apply the load spectrum. A new method to define the fuzzy acceleration factor based on the vibration signal is proposed. Then the whole test plan of accelerated reliability test is done.

  18. Harnessing Satellite Imageries in Feature Extraction Using Google Earth Pro

    Science.gov (United States)

    Fernandez, Sim Joseph; Milano, Alan

    2016-07-01

    Climate change has been a long-time concern worldwide. Impending flooding, for one, is among its unwanted consequences. The Phil-LiDAR 1 project of the Department of Science and Technology (DOST), Republic of the Philippines, has developed an early warning system in regards to flood hazards. The project utilizes the use of remote sensing technologies in determining the lives in probable dire danger by mapping and attributing building features using LiDAR dataset and satellite imageries. A free mapping software named Google Earth Pro (GEP) is used to load these satellite imageries as base maps. Geotagging of building features has been done so far with the use of handheld Global Positioning System (GPS). Alternatively, mapping and attribution of building features using GEP saves a substantial amount of resources such as manpower, time and budget. Accuracy-wise, geotagging by GEP is dependent on either the satellite imageries or orthophotograph images of half-meter resolution obtained during LiDAR acquisition and not on the GPS of three-meter accuracy. The attributed building features are overlain to the flood hazard map of Phil-LiDAR 1 in order to determine the exposed population. The building features as obtained from satellite imageries may not only be used in flood exposure assessment but may also be used in assessing other hazards and a number of other uses. Several other features may also be extracted from the satellite imageries.

  19. Harnessing the Collective Power of Eyewitnesses for Improved Earthquake Information

    Science.gov (United States)

    Bossu, R.; Lefebvre, S.; Mazet-Roux, G.; Steed, R.

    2013-12-01

    earthquakes within, as an average 90s of their occurrence, and can map, in certain cases, the damaged areas. Thanks to the flashsourced and crowdsourced information, we developed an innovative Twitter earthquake information service (currently under test and to be open by November) which intends to offer notifications for earthquakes that matter for the public only. It provides timely information for felt and damaging earthquakes regardless their magnitude and heads-up for seismologists. In conclusion, the experience developed at the EMSC demonstrates the benefit of involving eyewitnesses in earthquake surveillance. The data collected directly and indirectly from eyewitnesses complement information derived from monitoring networks and contribute to improved services. By increasing interaction between science and society, it opens new opportunities for raising awareness on seismic hazard.

  20. Evaluation of a Secure Laptop-Based Testing Program in an Undergraduate Nursing Program: Students' Perspective.

    Science.gov (United States)

    Tao, Jinyuan; Gunter, Glenda; Tsai, Ming-Hsiu; Lim, Dan

    2016-01-01

    Recently, the many robust learning management systems, and the availability of affordable laptops, have made secure laptop-based testing a reality on many campuses. The undergraduate nursing program at the authors' university began to implement a secure laptop-based testing program in 2009, which allowed students to use their newly purchased laptops to take quizzes and tests securely in classrooms. After nearly 5 years' secure laptop-based testing program implementation, a formative evaluation, using a mixed method that has both descriptive and correlational data elements, was conducted to seek constructive feedback from students to improve the program. Evaluation data show that, overall, students (n = 166) believed the secure laptop-based testing program helps them get hands-on experience of taking examinations on the computer and gets them prepared for their computerized NCLEX-RN. Students, however, had a lot of concerns about laptop glitches and campus wireless network glitches they experienced during testing. At the same time, NCLEX-RN first-time passing rate data were analyzed using the χ2 test, and revealed no significant association between the two testing methods (paper-and-pencil testing and the secure laptop-based testing) and students' first-time NCLEX-RN passing rate. Based on the odds ratio, however, the odds of students passing NCLEX-RN the first time was 1.37 times higher if they were taught with the secure laptop-based testing method than if taught with the traditional paper-and-pencil testing method in nursing school. It was recommended to the institution that better quality of laptops needs to be provided to future students, measures needed to be taken to further stabilize the campus wireless Internet network, and there was a need to reevaluate the Laptop Initiative Program.