Modern printers and hard copy devices for documentation in nuclear medicine

International Nuclear Information System (INIS)

Mahlstedt, J.

1987-01-01

Modern printers in nuclear medicine comprise technologies such as ink jet print, thermo transfer print or electrostatic plotting in combination with a digital processor. For clinical work these machines provide robust light weight copies within a short time thus fulfilling most of the criteria for an ideal documentation. (orig.) [de

Induction surface hardening of hard coated steels

Energy Technology Data Exchange (ETDEWEB)

Pantleon, K.; Kessler, O.; Hoffann, F.; Mayr, P. [Stiftung Inst. fuer Werkstofftechnik, Bremen (Germany)

1999-11-01

The properties of hard coatings deposited using CVD processes are usually excellent. However, high deposition temperatures negatively influence the substrate properties, especially in the case of low alloyed steels. Therefore, a subsequent heat treatment is necessary to restore the properties of steel substrates. Here, induction surface hardening is used as a method of heat treatment after the deposition of TiN hard coatings on AISI 4140 (DIN42CrMo4) substrates. The influences of the heat treatment on both the coating and the substrate properties are discussed in relation to the parameters of induction heating. Thereby, the heating time, heating atmosphere and the power input into the coating-substrate compounds are varied. As a result of induction surface hardening, the properties of the substrates are improved without losing good coating properties. High hardness values in the substrate near the interface allow the AISI 4140 substrates to support TiN hard coatings very well. Consequently, higher critical loads are measured in scratch tests after the heat treatment. Also, compressive residual stresses in the substrate are generated. In addition, only a very low distortion appears. (orig.)

Não-linearidades: da dinâmica do simples à dinâmica do complexo

Directory of Open Access Journals (Sweden)

José Roberto Castilho Piqueira

1994-01-01

Full Text Available Foram apresentados alguns conceitos relativos à utilização da Teoria dos Sistemas Dinâmicos em problemas de sistemas complexos. A apresentação destes conceitos centra-se no estabelecimento de duas dinâmicas: uma de curto termo e outra de longo termo, relacionando-as com os processos de organização dos sistemas.

Submerged arc narrow gap welding of the steel DIN 20MnMoNi55

International Nuclear Information System (INIS)

Moraes, M.M.

1987-01-01

The methodology for submerged arc narrow gap welding for high thickness rolled steel DIN 20MnMoNi55 was developed, using din S3NiMo1 04 mm and 05 mm wires, and DIN 8B435 flux. For this purpose, submerged arc narrow gap welded joints with 50 mm and 120 mm thickness were made aiming the welding parameters optimization and the study of the influence of welding voltage, wire diameter and wire to groove face distance on the operational performance and on the welded joint quality, specially on the ISO-V impact toughness. These welded joints were checked by non-destructive mechanical and metallographic tests. Results were compared with those obtained by one 120 mm thickness submerged arc conventional gap welded joint, using the same base metal and consumables (05 mm wire). The analysis of the results shows that the increasing of the wire to groove face distance and the welding voltage increases the hardness and the ISO-V impact toughness of the weld metal. It shows that the reduction of the gap angle is the main cause for the obtained of a heat affected zone free from coarse grains, the reduction of the welding voltage, the increasing of the wire to groove face distance, and the grounding optimization also contribute for that. It was also concluded that the quality and the execution complexity level of a narrow gap welded joint are identical to a conventional gap welded joint. (author) [pt

Ernst Rüdin, 1874-1952: a German psychiatrist and geneticist.

Science.gov (United States)

Weber, M M

1996-07-26

Ernst Rüdin (1874-1952) was one of the major representatives of German psychiatry, genetics, and eugenics in the first half of the twentieth century. Born in Switzerland, he was influenced early on by his brother-in-law Alfred Ploetz, who propagated the ideas of social Darwinism and "racial hygiene" in Germany after 1890. Rüdin began his career in psychiatry at Emil Kraepelin's clinic in Munich, where he developed the concept of "empirical genetic prognosis" of mental disorders. He published his first results on the genetics of schizophrenia in 1916. From 1917-1945 Rüdin was director of the Genealogical-Demographic Department at the German Institute for Psychiatric Research, which Kraepelin had founded. After a short interruption from 1925-1928, Rüdin returned to Munich and enlarged the department. After 1933 the National Socialist government and party endorsed Rüdin's work by supplying financial and manpower support. Nazi health policy required a scientific basis to justify its actions, and Rüdin's ideas corresponded partially with this kind of thinking. In 1934 he prepared the official commentary on the "Law for the Prevention of Genetically Diseased Offspring." The connections of Rüdin's department to National Socialism can be understood as one of the main reasons for the critical attitude towards psychiatric genetics in Germany after 1945.

The Use of Plasma Technique in Nitridation Process of Metal Alloy DIN 42CrMo4

International Nuclear Information System (INIS)

Purwanto; Malau, Viktor; Tjipto Sujitno

2003-01-01

Nitridation process with plasma technique is one of technique for surface treatment of a material. Research on plasma technique for nitridation process has been carried out to find out the nitridation effect on properties of metal alloy DIN 42CrM04. Nitridation process with plasma technique was conducted in a vacuum tube under following conditions 0.36 torr of pressure, 300 o C of temperature and nitridation times 1, 2, and 3 hours. Nitridation process was followed by hardness test measurement using High Quality Micro Hardness Tester machine, serial number MM-0054, as well as microstructure test using Scanning Electron Microscope (SEM) coupled with Energy Dispersive Spectroscopy (EDS) EDAX-DX4. The results showed that surface hardness increased after nitridation process. For nitridation processes for 1, 2, and 3 hours, the hardness increased from 291 kg/mm 2 to 303 kg/mm 2 , 324 kg/mm 2 and 403 kg/mm 2 , respectively. The results from micro structure observation showed that new phase of Ferro Nitride (Fe 4 N) has been formed with 4.17% nitrogen weight equivalent to 14.73% nitrogen atom and with the thickness of 5.71 μm, 5.08% nitrogen weight or 17.51% nitrogen atom and 6.78 μm thickness, and 5.69% nitrogen weight or 19.24% nitrogen atom and 8.57 μm thickness. (author)

Entrenamiento integrado. Principios dinámicos y aplicaciones

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Natàlia Balagué Serre

2014-06-01

Full Text Available El interés por el entrenamiento integrado es creciente y para aumentar su eficacia resulta clave conocer cómo se produce el proceso de integración en los sistemas vivos. Por lo general, se suele asumir que el tipo de integración que se da en el organismo y entre los componentes del entrenamiento es sumatoria y lineal; es decir, está caracterizada por relaciones proporcionales, fijas e invariables en el tiempo, como las que se dan en cualquier artilugio técnico. Este modelo de integración, basado en la cibernética clásica, contrasta con el modelo de integración dinámica y no lineal, asentado en la neurociencia, la teoría de sistemas dinámicos no lineales, y la dinámica ecológica. Algunos principios de la integración dinámica y no lineal como la autoorganización, su carácter no proporcional y no consciente y su integración contextual en diferentes escalas acostumbran a ignorarse sistemáticamente en las metodologías de entrenamiento más habituales. El objetivo de este trabajo es presentar los principios dinámicos del entrenamiento integrado para promover la emergencia de metodologías más eficaces y eficientes a la vez que más respetuosas con los deportistas y los equipos.

DIN VIAŢĂ SI DIN CĂRŢI O LUCRARE CE NE PUNE PE GÂNDURI

Directory of Open Access Journals (Sweden)

Coriolan PĂUNESCU

2008-06-01

Full Text Available A apărut, la Iasi, o carte cu valoare de unicat; este vorba de „Agriculturaîn proverbe si cugetări” (Ed. Vasiliana ’98, Iasi, 2008, semnată de reputatul Prof.univ. dr. Nicolae VASILESCU si ing. Aglaia VASILESCU, oameni care au slujitdecenii de-a rândul învăţământul agronomic românesc. De aici, desigur si respectulautorilor pentru agricultură si, mai ales, pentru oamenii satului, dedicaţi, înîntregime, acestei nobile îndeletniciri (dar si creaţiei lor spirituale, în care, nu o dată,se reflectă munca si viaţa de fiecare zi. Însă, această carte se vrea mai mult decâtspune, deoarece cuprinde si reflecţii ale oamenilor culţi, despre agricultură, întrecare scriitori, filosofi, muzicieni, savanţi ai domeniului agronomic, călătoriînvederaţi, politicieni, istorici, oameni ai catedrelor, revoluţionari de renume,evident, din lume si din ţară, din Antichitate si până astăzi.

Estimating the Probability of Traditional Copying, Conditional on Answer-Copying Statistics.

Science.gov (United States)

Allen, Jeff; Ghattas, Andrew

2016-06-01

Statistics for detecting copying on multiple-choice tests produce p values measuring the probability of a value at least as large as that observed, under the null hypothesis of no copying. The posterior probability of copying is arguably more relevant than the p value, but cannot be derived from Bayes' theorem unless the population probability of copying and probability distribution of the answer-copying statistic under copying are known. In this article, the authors develop an estimator for the posterior probability of copying that is based on estimable quantities and can be used with any answer-copying statistic. The performance of the estimator is evaluated via simulation, and the authors demonstrate how to apply the formula using actual data. Potential uses, generalizability to other types of cheating, and limitations of the approach are discussed.

Standard hardness conversion tables for metals relationship among brinell hardness, vickers hardness, rockwell hardness, superficial hardness, knoop hardness, and scleroscope hardness

CERN Document Server

American Society for Testing and Materials. Philadelphia

2007-01-01

1.1 Conversion Table 1 presents data in the Rockwell C hardness range on the relationship among Brinell hardness, Vickers hardness, Rockwell hardness, Rockwell superficial hardness, Knoop hardness, and Scleroscope hardness of non-austenitic steels including carbon, alloy, and tool steels in the as-forged, annealed, normalized, and quenched and tempered conditions provided that they are homogeneous. 1.2 Conversion Table 2 presents data in the Rockwell B hardness range on the relationship among Brinell hardness, Vickers hardness, Rockwell hardness, Rockwell superficial hardness, Knoop hardness, and Scleroscope hardness of non-austenitic steels including carbon, alloy, and tool steels in the as-forged, annealed, normalized, and quenched and tempered conditions provided that they are homogeneous. 1.3 Conversion Table 3 presents data on the relationship among Brinell hardness, Vickers hardness, Rockwell hardness, Rockwell superficial hardness, and Knoop hardness of nickel and high-nickel alloys (nickel content o...

Duygusal Zeka Din Öğretimi; Din Kültürü ve Ahlak Bilgisi Dersi ve Duygusal Zeka Gelişim İlişkisi

Directory of Open Access Journals (Sweden)

Remziye Ege

2015-11-01

Full Text Available Duygusal zeka, bireyin, kendi duygularını anlaması, başkalarıın duygularına empati  beslemesi, duygu yönetimi, motivasyon ve duygularını yaşamı zenginleştirecek biçimde düzenleyebilme yetisi olarak tanımlanmaktadır. Din öğretimi yoluyla duygusal zeka becerilerinin ve yerisinin elde edileceği ve geliştirileceği düşünülmektedir. Bu makalede İlköğretim Din Kültürü ve Ahlak Bilgisi Dersinin muhtevasından hareketle duygusal zeka gelişimi ile din öğretimi arasındaki paralel ilişkiye dikkat çekmek hedeflenmiştir. Söz konusu ilişki, din öğretiminin inanç, ibadet, dua, ahlak öğretim alanlarındaki konulardan örnekler üzerinde belirtilmiştir. Duygusal zeka, bireyin, kendi duygularını anlaması, başkalannın duygulanna empati beslemesi, duygu yönetimi, motivasyon ve duygularını yaşamı zenginleştirecek biçimde düzenleyebilme yetisi olarak tanımlanmaktadır. Din öğretimi yoluyla duygusal zeka becerilerinin ve yerisinin elde edileceği ve geliştirileceği düşünülmektedir. Bu makalede İlköğretim Din Kültürü ve Ahlak Bilgisi Dersinin muhtevasından hareketle duygusal zeka gelişimi ile din öğretimi arasındaki paralel ilişkiye dikkat çekmek hedeflenmiştir. Söz konusu ilişki, din öğretiminin inanç, ibadet, dua, ahlak öğretim alanlarındaki konulardan örnekler üzerinde belirtilmiştir

Escherichia coli DinB inhibits replication fork progression without significantly inducing the SOS response.

Science.gov (United States)

Mori, Tetsuya; Nakamura, Tatsuro; Okazaki, Naoto; Furukohri, Asako; Maki, Hisaji; Akiyama, Masahiro Tatsumi

2012-01-01

The SOS response is readily triggered by replication fork stalling caused by DNA damage or a dysfunctional replicative apparatus in Escherichia coli cells. E. coli dinB encodes DinB DNA polymerase and its expression is upregulated during the SOS response. DinB catalyzes translesion DNA synthesis in place of a replicative DNA polymerase III that is stalled at a DNA lesion. We showed previously that DNA replication was suppressed without exogenous DNA damage in cells overproducing DinB. In this report, we confirm that this was due to a dose-dependent inhibition of ongoing replication forks by DinB. Interestingly, the DinB-overproducing cells did not significantly induce the SOS response even though DNA replication was perturbed. RecA protein is activated by forming a nucleoprotein filament with single-stranded DNA, which leads to the onset of the SOS response. In the DinB-overproducing cells, RecA was not activated to induce the SOS response. However, the SOS response was observed after heat-inducible activation in strain recA441 (encoding a temperature-sensitive RecA) and after replication blockage in strain dnaE486 (encoding a temperature-sensitive catalytic subunit of the replicative DNA polymerase III) at a non-permissive temperature when DinB was overproduced in these cells. Furthermore, since catalytically inactive DinB could avoid the SOS response to a DinB-promoted fork block, it is unlikely that overproduced DinB takes control of primer extension and thus limits single-stranded DNA. These observations suggest that DinB possesses a feature that suppresses DNA replication but does not abolish the cell's capacity to induce the SOS response. We conclude that DinB impedes replication fork progression in a way that does not activate RecA, in contrast to obstructive DNA lesions and dysfunctional replication machinery.

Kommunikation skaber din organisation

DEFF Research Database (Denmark)

Hansen, Heidi

KOMMUNIKATION skaber din ORGANISATION tager udgangspunkt i en narrativ tilgang til kommunikation, hvor organisationen skabes i mødet mellem ledere, medarbejdere, organisation og omverden. Historier hjælper os med at skabe mening, og er derfor vigtige både som et udviklingsværktøj i organisationen...

Electrodeposition of Nanocrystalline Co-P Coatings as a Hard Chrome Alternative (Briefing Charts)

Science.gov (United States)

2011-02-10

chrome plating utilizes chromium in the hexavalent state (Cr6+) Cr6+ is a known carcinogen and poses a health risk to operators OSHA lowered the Cr6+ PEL...from 52 µg/m3 to 5 µg/m3 8 Apr 09, Memorandum, DoD Directive Hexavalent Chromium Management Policy NAVAIR Cr6+ Authorization Process Hard Chrome ...Aerospace & Defense February 10, 2011 Electrodeposition of Nanocrystalline Co-P Coatings as a Hard Chrome Alternative Jack Benfer Co-PI NAVAIR

Comportamento dinâmico de um modelo simples solo-estrutura

OpenAIRE

Gonçalves, Fábio André Vaz

2012-01-01

Dissertação para obtencão do Grau de Mestre em Engenharia Civil - Perfil Estruturas O comportamento de uma estrutura sujeita a cargas dinâmicas depende de características como a massa, a rigidez dos vários elementos e da capacidade de dissipação de energia. A resposta dinâmica da estrutura apoiada num solo depende das propriedades dinâmicas dos dois sistemas. A resposta do sistema é influenciada pelos efeitos de interacção solo-estrutura. Nesta dissertação estudou-se um m...

Gauge field copies

International Nuclear Information System (INIS)

Bollini, C.G.; Giambiagi, J.J.; Tiomno, J.

1979-01-01

The construction of field strength copies without any gauge constraint is discussed. Several examples are given, one of which is not only a field strength copy but also (at the same time) a 'current copy'. (author) [pt

Una solución dinámica para juegos con utilidades transferibles

Directory of Open Access Journals (Sweden)

Juan Carlos Cesco

2008-01-01

Full Text Available En este trabajo definimos un tipo de solución dinámica para juegos con utilidades transferibles. La solución dinámica fue introducida por Shenoy (1980 en el marco de juegos abstractos como un medio para describir algunos procesos de negociación. En el contexto de los juegos con utilidades transferibles estudiamos su comportamiento tanto en la clase de los juegos equilibrados (con Core no vacío como en el de los juegos no equilibrados. En esta última subclase mostramos que la solución dinámica debe contener los elementos de ciertos ciclos de preimputaciones denominados ciclos maximales. Estos ciclos aparecen en relación con un esquema dinámico elaborado originalmente para aproximar puntos en el Core de un juego. En la subclase de los juegos equilibrados, la solución dinámica coincide con el Core, lo que establece un enfoque unificado de solución. El problema de existencia de ciclos maximales no está completamente resuelto, pero en algunas subclases de juegos podemos exhibir teoremas de existencia y una descripción completa de la solución dinámica.

Radiographic sensitivity evaluated by IQI DIN in double wall radiography and simple view

International Nuclear Information System (INIS)

Oliveira, C.S. de; Santos Filho, M. dos

1983-01-01

A comparison between the sensitivity of IQI-DIN put at the film side with the sensitivity of the IQI-DIN put at the source side, only for the double wall-simple view technique (DW-SW) is presented. An analysis about the requirements of radiographyic sensitivity in accordance to DIN rule is done. (E.G.) [pt

A ΔdinB mutation that sensitizes Escherichia coli to the lethal effects of UV- and X-radiation

Energy Technology Data Exchange (ETDEWEB)

Lee, Mei-Chong W.; Franco, Magdalena; Vargas, Doris M. [Department of Biological Sciences, San Jose State University, San Jose, CA 95192 (United States); Hudman, Deborah A. [Department of Microbiology and Immunology, A.T. Still University, Kirksville College of Osteopathic Medicine, Kirksville, MO 63501 (United States); White, Steven J. [Department of Biological Sciences, San Jose State University, San Jose, CA 95192 (United States); Fowler, Robert G., E-mail: rfowler@sjsu.edu [Department of Biological Sciences, San Jose State University, San Jose, CA 95192 (United States); Sargentini, Neil J. [Department of Microbiology and Immunology, A.T. Still University, Kirksville College of Osteopathic Medicine, Kirksville, MO 63501 (United States)

2014-05-15

Highlights: • We describe Δ(dinB-yafN)883(::kan), a novel dinB allele, referred to as ΔdinB883, a deletion that sensitizes E. coli cells to UV irradiation. • This UV radiation sensitivity is most acute in the early logarithmic phase of culture growth. • This UV radiation sensitivity is completely dependent upon a functional umuDC operon. • Sequencing reveals ΔdinB883 retains the proximal 161 nucleotides, i.e., 54 amino acids, of the wild-type sequence. • The ΔdinB883 mutant is hypothesized to produce a peptide of 83 amino acids, DinB883, that compromises UmuDC function. - Abstract: The DinB (PolIV) protein of Escherichia coli participates in several cellular functions. We investigated a dinB mutation, Δ(dinB-yafN)883(::kan) [referred to as ΔdinB883], which strongly sensitized E. coli cells to both UV- and X-radiation killing. Earlier reports indicated dinB mutations had no obvious effect on UV radiation sensitivity which we confirmed by showing that normal UV radiation sensitivity is conferred by the ΔdinB749 allele. Compared to a wild-type strain, the ΔdinB883 mutant was most sensitive (160-fold) in early to mid-logarithmic growth phase and much less sensitive (twofold) in late log or stationary phases, thus showing a growth phase-dependence for UV radiation sensitivity. This sensitizing effect of ΔdinB883 is assumed to be completely dependent upon the presence of UmuDC protein; since the ΔdinB883 mutation did not sensitize the ΔumuDC strain to UV radiation killing throughout log phase and early stationary phase growth. The DNA damage checkpoint activity of UmuDC was clearly affected by ΔdinB883 as shown by testing a umuC104 ΔdinB883 double-mutant. The sensitivities of the ΔumuDC strain and the ΔdinB883 ΔumuDC double-mutant strain were significantly greater than for the ΔdinB883 strain, suggesting that the ΔdinB883 allele only partially suppresses UmuDC activity. The ΔdinB883 mutation partially sensitized (fivefold) uvrA and uvr

Scaling up Copy Detection

OpenAIRE

Li, Xian; Dong, Xin Luna; Lyons, Kenneth B.; Meng, Weiyi; Srivastava, Divesh

2015-01-01

Recent research shows that copying is prevalent for Deep-Web data and considering copying can significantly improve truth finding from conflicting values. However, existing copy detection techniques do not scale for large sizes and numbers of data sources, so truth finding can be slowed down by one to two orders of magnitude compared with the corresponding techniques that do not consider copying. In this paper, we study {\\em how to improve scalability of copy detection on structured data}. Ou...

Multiple pathways for SOS-induced mutagenesis in Escherichia coli: An overexpression of dinB/dinP results in strongly enhancing mutagenesis in the absence of any exogenous treatment to damage DNA

Science.gov (United States)

Kim, Su-Ryang; Maenhaut-Michel, Geneviéve; Yamada, Masami; Yamamoto, Yoshihiro; Matsui, Keiko; Sofuni, Toshio; Nohmi, Takehiko; Ohmori, Haruo

1997-01-01

dinP is an Escherichia coli gene recently identified at 5.5 min of the genetic map, whose product shows a similarity in amino acid sequence to the E. coli UmuC protein involved in DNA damage-induced mutagenesis. In this paper we show that the gene is identical to dinB, an SOS gene previously localized near the lac locus at 8 min, the function of which was shown to be required for mutagenesis of nonirradiated λ phage infecting UV-preirradiated bacterial cells (termed λUTM for λ untargeted mutagenesis). A newly constructed dinP null mutant exhibited the same defect for λUTM as observed previously with a dinB::Mu mutant, and the defect was complemented by plasmids carrying dinP as the only intact bacterial gene. Furthermore, merely increasing the dinP gene expression, without UV irradiation or any other DNA-damaging treatment, resulted in a strong enhancement of mutagenesis in F′lac plasmids; at most, 800-fold increase in the G6-to-G5 change. The enhanced mutagenesis did not depend on recA, uvrA, or umuDC. Thus, our results establish that E. coli has at least two distinct pathways for SOS-induced mutagenesis: one dependent on umuDC and the other on dinB/P. PMID:9391106

Protection of proprietary rights of DIN standards in connection with statutory and administrative provisions

International Nuclear Information System (INIS)

Katzenberger, P.

1985-01-01

On the basis of contracts entered with the German Institute of Standardization (DIN), the state bodies and authorities tend to refer to Din standards in many ways when issuing statutory or administrative provisions. Some Din standards are also printed in official publications- with or without Din's prior consent. Such common practice leads to the question whether the Din standards which on pinciple meet the general requirements made on the protection of proprietary rights are losing this protection by the fact that official publications are exempt from the protection of proprietary rights (Art.5 UrhG). The author points out that the thorough analysis of the legal position in terms of interests, proprietary rights and constitution indicated that this is not, in principle, the case. (orig.) [de

Original Copies

DEFF Research Database (Denmark)

Sørensen, Tim Flohr

2013-01-01

of similarity by looking at artefactual similarity as the results of prototyping and as a production of simulacra. In this light, the concept of copying turns out to be more than simply a matter of trying to imitate an exotic or prestigious original, and it fundamentally raises the question how different a copy...

Quantum copying: A review

Directory of Open Access Journals (Sweden)

Mark Hillery

2000-07-01

Full Text Available Quantum information is stored in two-level quantum systems known as qubits. The no-cloning theorem states that the state of an unknown qubit cannot be copied. This is in contrast to classical information which can be copied. If one drops the requirement that the copies be perfect it is possible to design quantum copiers. This paper presents a short review of the theory of quantum copying.

Analisis Kecenderungan Manhaj Akidah Shaykh Shams al-Din al-Sumatera’i

Directory of Open Access Journals (Sweden)

MOHD HAIDHAR KAMARZAMAN

2016-12-01

Full Text Available Shaykh Shams al-Din al-Sumatera'i is a very great and respected scholar during 16th and 17th century of Acheh. His knowledge in various fields recognized by local and international scholars. He had been a Qadi Malik al-’Adil, a religious leader, who became a referred by communities and country during the reign of the three Sultans of Aceh. He has authored nearly 40 pieces of books related to the theology and sufism. This study focuses on the methods used by Shaykh Shams al-Din al-Sumatera'i in his theological writings. This study found that Shaykh Shams al-Din al-Sumatera'i had used six methods in the such writings.

Localized landslide risk assessment with multi pass L band DInSAR analysis

Science.gov (United States)

Yun, HyeWon; Rack Kim, Jung; Lin, Shih-Yuan; Choi, YunSoo

2014-05-01

In terms of data availability and error correction, landslide forecasting by Differential Interferometric SAR (DInSAR) analysis is not easy task. Especially, the landslides by the anthropogenic construction activities frequently occurred in the localized cutting side of mountainous area. In such circumstances, it is difficult to attain sufficient enough accuracy because of the external factors inducing the error component in electromagnetic wave propagation. For instance, the local climate characteristics such as orographic effect and the proximity to water source can produce the significant anomalies in the water vapor distribution and consequently result in the error components of InSAR phase angle measurements. Moreover the high altitude parts of target area cause the stratified tropospheric delay error in DInSAR measurement. The other obstacle in DInSAR observation over the potential landside site is the vegetation canopy which causes the decorrelation of InSAR phase. Thus rather than C band sensor such as ENVISAT, ERS and RADARSAT, DInSAR analysis with L band ALOS PLASAR is more recommendable. Together with the introduction of L band DInSAR analysis, the improved DInSAR technique to cope all above obstacles is necessary. Thus we employed two approaches i.e. StaMPS/MTI (Stanford Method for Persistent Scatterers/Multi-Temporal InSAR, Hopper et al., 2007) which was newly developed for extracting the reliable deformation values through time series analysis and two pass DInSAR with the error term compensation based on the external weather information in this study. Since the water vapor observation from spaceborne radiometer is not feasible by the temporal gap in this case, the quantities from weather Research Forecasting (WRF) with 1 km spatial resolution was used to address the atmospheric phase error in two pass DInSAR analysis. Also it was observed that base DEM offset with time dependent perpendicular baselines of InSAR time series produce a significant error

The Art of Copying

DEFF Research Database (Denmark)

Christensen, Hans Dam

2017-01-01

This article discusses copies within the field of art museums by way of mapping strategies for copy practices. This mapping leans heavily towards parts of the writings of Jacques Derrida (1930–2004). Against the backdrop of this theoretical premise, the article distinguishes five main strategies....... An informational copy is just as unique as an original object of art, and at the same time, it defines the original and is itself defined by this opposition. Lastly, the strategy for the imagined relation between original and copy follows. This strategy is dependent upon several of the previous approaches, and...

Robust Adaptable Video Copy Detection

DEFF Research Database (Denmark)

Assent, Ira; Kremer, Hardy

2009-01-01

in contrast). Our query processing combines filtering and indexing structures for efficient multistep computation of video copies under this model. We show that our model successfully identifies altered video copies and does so more reliably than existing models.......Video copy detection should be capable of identifying video copies subject to alterations e.g. in video contrast or frame rates. We propose a video copy detection scheme that allows for adaptable detection of videos that are altered temporally (e.g. frame rate change) and/or visually (e.g. change...

IMUNOREACTIVITATEA ÎNCRUCIŞATĂ POTENŢIALĂ A GLOBULINELOR DE REZERVĂ DIN SEMINŢE

Directory of Open Access Journals (Sweden)

Ala CHERDIVARĂ

2018-03-01

Full Text Available Globulinele de rezervă 7S şi 11S din seminţele de arahide şi de soia, ca ingrediente naturale ale alimentelor, pot determina dezvoltarea reacţiei alergice cauzate de formarea intensivă a imunoglobulinelor E (IgE alergen specifice. Secvenţele de aminoacizi ale globulinelor de rezervă din seminţe sunt conservative; prin urmare, în secvenţele multora dintre ele există situsuri care sunt similare în structura primară a epitopilor IgE, ceea ce determină alergenicitatea glo­bu­linelor 7S şi 11S din arahide şi soia. În prezentul studiu a fost efectuată o evaluare cantitativă a probabilităţii prezenţei epitopilor IgE, care determină imunoreactivitatea încrucişată stabilită a globulinelor de rezervă din arahide şi din soia în globulinele 7S şi 11S din seminţele altor plante.A fost efectuată o estimare cantitativă a probabilității prezenței epitopilor IgE ce determină imunoreactivitatea încrucișată stabilită a globulinelor de rezervă din arahide și soia în secvențele de aminoacizi ale globulinelor 7S și 11S din semințele altor plante.POTENTIAL CROSS IMMUNOREACTIVITY OF SEED STORAGE GLOBULINSSeed storage 7S and 11S globulins of peanut and soybean as natural components of food can lead to the development of increased allergic sensitivity caused by the intensive formation of allergen-specific immunoglobulin E (IgE. The amino acid sequences of the seed storage globulins are conservative, therefore, in the sequences of many of them there are sites that are close similar of IgE epitopes of 7S and 11S globulins of peanuts and soybeans.In the present work, a quantitative assessment of the probability of the presence of IgE epitopes determining the established cross immunoreactivity of seed storage globulins of peanuts and soybeans, in the sequences of 7S and 11S seed storage globulins of other plants was carried out.

A novel cis-acting element required for DNA damage-inducible expression of yeast DIN7

International Nuclear Information System (INIS)

Yoshitani, Ayako; Yoshida, Minoru; Ling Feng

2008-01-01

Din7 is a DNA damage-inducible mitochondrial nuclease that modulates the stability of mitochondrial DNA (mtDNA) in Saccharomyces cerevisiae. How DIN7 gene expression is regulated, however, has remained largely unclear. Using promoter sequence alignment, we found a highly conserved 19-bp sequence in the promoter regions of DIN7 and NTG1, which encodes an oxidative stress-inducible base-excision-repair enzyme. Deletion of the 19-bp sequence markedly reduced the hydroxyurea (HU)-enhanced DIN7 promoter activity. In addition, nuclear fractions prepared from HU-treated cells were used in in vitro band shift assays to reveal the presence of currently unidentified trans-acting factor(s) that preferentially bound to the 19-bp region. These results suggest that the 19-bp sequence is a novel cis-acting element that is required for the regulation of DIN7 expression in response to HU-induced DNA damage

Planificación de trayectorias para un robot tipo con restricciones dinámicas

Directory of Open Access Journals (Sweden)

Leonardo Solaque Guzmán

2008-01-01

Full Text Available Este documento presenta una aproximación a la planificación de caminos óptimos para un sistema con restricciones dinámicas y desplazándose dentro de un espacio libre de obstáculos. Se considera el modelo dinámico del dirigible y un análisis para el planteamiento de modelos simplificados o comúnmente conocidos como modelos de control. Se propone una planificación de la trayectoria desde el punto de vista de la teoría óptima utilizando un modelo de la dinámica de un robot móvil (que se desplaza a velocidad constante y en avance, es decir con restricciones dinámicas como punto de partida para la primera aproximación a los caminos óptimos. Para el suavizado de las trayectorias del dirigible se proponen dos modelos con relajación en la dinámica de la variable de control y finalmente se presenta una simulación de la comparación de los diferentes resultados.

Seasonal and multi-year surface displacements measured by DInSAR in a High Arctic permafrost environment

Science.gov (United States)

Rudy, Ashley C. A.; Lamoureux, Scott F.; Treitz, Paul; Short, Naomi; Brisco, Brian

2018-02-01

Arctic landscapes undergo seasonal and long-term changes as the active layer thaws and freezes, which can result in localized or irregular subsidence leading to the formation of thermokarst terrain. Differential Interferometric Synthetic Aperture Radar (DInSAR) is a technique capable of measuring ground surface displacements resulting from thawing permafrost at centimetre precision and is quickly gaining acceptance as a means of measuring ground displacement in permafrost regions. Using RADARSAT-2 stacked DInSAR data from 2013 and 2015 we determined the magnitude and patterns of land surface change in a continuous permafrost environment. At our study site situated in the Canadian High Arctic, DInSAR seasonal ground displacement patterns were consistent with field observations of permafrost degradation. As expected, many DInSAR values are close to the detection threshold (i.e., 1 cm) and therefore do not indicate significant change; however, DInSAR seasonal ground displacement patterns aligned well with climatological and soil conditions and offer geomorphological insight into subsurface processes in permafrost environments. While our dataset is limited to two years of data representing a three-year time period, the displacements derived from DInSAR provide insight into permafrost change in a High Arctic environment and demonstrate that DInSAR is an applicable tool for understanding environmental change in remote permafrost regions.

[DIN-compatible vision assessment of increased reproducibility using staircase measurement and maximum likelihood analysis].

Science.gov (United States)

Weigmann, U; Petersen, J

1996-08-01

Visual acuity determination according to DIN 58,220 does not make full use of the information received about the patient, in contrast to the staircase method. Thus, testing the same number of optotypes, the staircase method should yield more reproducible acuity results. On the other hand, the staircase method gives systematically higher acuity values because it converges on the 48% point of the psychometric function (for Landolt rings in eight positions) and not on the 65% probability, as DIN 58,220 with criterion 3/5 does. This bias can be avoided by means of a modified evaluation. Using the staircase data we performed a maximum likelihood estimate of the psychometric function as a whole and computed the acuity value for 65% probability of correct answers. We determined monocular visual acuity in 102 persons with widely differing visual performance. Each subject underwent four tests in random order, two according to DIN 58,220 and two using the modified staircase method (Landolt rings in eight positions scaled by a factor 1.26; PC monitor with 1024 x 768 pixels; distance 4.5 m). Each test was performed with 25 optotypes. The two procedures provide the same mean visual acuity values (difference less than 0.02 acuity steps). The test-retest results match in 30.4% of DIN repetitions but in 50% of the staircases. The standard deviation of the test-retest difference is 1.41 (DIN) and 1.06 (modified staircase) acuity steps. Thus the standard deviation of the single test is 1.0 (DIN) and 0.75 (modified staircase) acuity steps. The new method provides visual acuity values identical to DIN 58,220 but is superior with respect to reproducibility.

Temas de Física para Ingeniería: Dinámica del punto material

OpenAIRE

Beléndez, Augusto; Pastor Antón, Carlos; Bernabeu, Guillermo

1988-01-01

Apuntes de Mecánica: "Dinámica del punto material". Introducción, dinámica del punto. Fuerzas en la naturaleza. Sistemas de referencia. Leyes de Newton. Fuerzas de rozamiento. Ley de la gravitación universal. Aplicación de las leyes de Newton a la resolución de problemas de dinámica. Momento lineal y conservación. Redefinición de fuerza. Momento angular y conservación, fuerzas centrales. Impulso mecánico.

Barandillas de protección personal con solicitación dinámica

Directory of Open Access Journals (Sweden)

Pomares, J. C.

2013-06-01

Full Text Available Safety guardrails with dynamic loads, B and C types conforming EN 13374, are devices used as collective protection for people against height falls and for retaining materials. This system can include a safety net anchored to a support structure for its vertical use (U system, EN 1263. In this paper, fundamental aspects are analysed, as design, mechanical requirements and solution for the hard points that arise at supports of the system, able to seriously injure falling people. So, a ballast fall against this system has been studied, by modelling it with dynamic finite elements and analytical kinetic considerations, to obtain useful conclusions about geometry, cross section of the supports, maximum deflection and impact factor over the injured. It allows to suggest normative text improvements.Las barandillas de seguridad con solicitación dinámica, tipos B y C según UNE-EN 13374, son el conjunto de componentes destinados a la protección colectiva de las personas contra las caídas a un nivel inferior y a retener materiales. Frecuentemente incorporan una red de seguridad. En este artículo se analizan aspectos fundamentales como su diseño, sus requisitos mecánicos y la solución a la problemática que suponen los soportes o puntos duros capaces de producir lesiones al accidentado. Para este fin, se ha estudiado el fenómeno de la caída de un lastre sobre tales redes con distintos modelos numéricos de elementos finitos en régimen dinámico y mediante consideraciones analíticas cinemáticas, obteniendo conclusiones útiles como la forma geométrica necesaria, la escuadría de los perfiles que constituyen el bastidor de la red, y los factores de impacto que sufren los accidentados. Ello permite sugerir mejoras al texto normativo.

Work Hard / Play Hard

OpenAIRE

Burrows, J.; Johnson, V.; Henckel, D.

2016-01-01

Work Hard / Play Hard was a participatory performance/workshop or CPD experience hosted by interdisciplinary arts atelier WeAreCodeX, in association with AntiUniversity.org. As a socially/economically engaged arts practice, Work Hard / Play Hard challenged employees/players to get playful, or go to work. 'The game changes you, you never change the game'. Employee PLAYER A 'The faster the better.' Employer PLAYER B

DinB Upregulation Is the Sole Role of the SOS Response in Stress-Induced Mutagenesis in Escherichia coli

Science.gov (United States)

Galhardo, Rodrigo S.; Do, Robert; Yamada, Masami; Friedberg, Errol C.; Hastings, P. J.; Nohmi, Takehiko; Rosenberg, Susan M.

2009-01-01

Stress-induced mutagenesis is a collection of mechanisms observed in bacterial, yeast, and human cells in which adverse conditions provoke mutagenesis, often under the control of stress responses. Control of mutagenesis by stress responses may accelerate evolution specifically when cells are maladapted to their environments, i.e., are stressed. It is therefore important to understand how stress responses increase mutagenesis. In the Escherichia coli Lac assay, stress-induced point mutagenesis requires induction of at least two stress responses: the RpoS-controlled general/starvation stress response and the SOS DNA-damage response, both of which upregulate DinB error-prone DNA polymerase, among other genes required for Lac mutagenesis. We show that upregulation of DinB is the only aspect of the SOS response needed for stress-induced mutagenesis. We constructed two dinB(oc) (operator-constitutive) mutants. Both produce SOS-induced levels of DinB constitutively. We find that both dinB(oc) alleles fully suppress the phenotype of constitutively SOS-“off” lexA(Ind−) mutant cells, restoring normal levels of stress-induced mutagenesis. Thus, dinB is the only SOS gene required at induced levels for stress-induced point mutagenesis. Furthermore, although spontaneous SOS induction has been observed to occur in only a small fraction of cells, upregulation of dinB by the dinB(oc) alleles in all cells does not promote a further increase in mutagenesis, implying that SOS induction of DinB, although necessary, is insufficient to differentiate cells into a hypermutable condition. PMID:19270270

La flexibilitat en els àcids nucleics: Un estudi de dinàmica molecular

OpenAIRE

Noy Freixa, Agnès

2008-01-01

[cat] L'estat de l'art de les simulacions de dinàmica molecular és utilitzat per estudiar l'estructura, dinàmica, propietats d'interacció molecular i flexibilitat dels dúplexs d'ADN i ARN en solució acuosa. Les nostres simulacions suggereixen que el concepte de flexibilitat, rigidesa i deformabilitat són molt més complexes del que habitualment es creu, i que per tant no és sempre veritat que l'ADN sigui més flexible que l'ARN. La dinàmica molecular és a més utilitzada per investigar les prop...

Flexibilitat en els àcids nucleics: Un estudi de dinàmica molecular, La

OpenAIRE

Noy Freixa, Agnès

2008-01-01

L'estat de l'art de les simulacions de dinàmica molecular és utilitzat per estudiar l'estructura, dinàmica, propietats d'interacció molecular i flexibilitat dels dúplexs d'ADN i ARN en solució acuosa. Les nostres simulacions suggereixen que el concepte de flexibilitat, rigidesa i deformabilitat són molt més complexes del que habitualment es creu, i que per tant no és sempre veritat que l'ADN sigui més flexible que l'ARN.La dinàmica molecular és a més utilitzada per investigar les propietats d...

Hard electronics; Hard electronics

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-03-01

Hard material technologies were surveyed to establish the hard electronic technology which offers superior characteristics under hard operational or environmental conditions as compared with conventional Si devices. The following technologies were separately surveyed: (1) The device and integration technologies of wide gap hard semiconductors such as SiC, diamond and nitride, (2) The technology of hard semiconductor devices for vacuum micro- electronics technology, and (3) The technology of hard new material devices for oxides. The formation technology of oxide thin films made remarkable progress after discovery of oxide superconductor materials, resulting in development of an atomic layer growth method and mist deposition method. This leading research is expected to solve such issues difficult to be easily realized by current Si technology as high-power, high-frequency and low-loss devices in power electronics, high temperature-proof and radiation-proof devices in ultimate electronics, and high-speed and dense- integrated devices in information electronics. 432 refs., 136 figs., 15 tabs.

NCRP Report No.151 versus Norm DIN 6847-2; NCRP Report No. 151 vs Norma DIN 6847-2

Energy Technology Data Exchange (ETDEWEB)

Sanchez Jimenez, J.; Rivas Ballarin, M. A.

2008-07-01

The National Council on Radiation protection and Measurements (NCRP) has recently published its Report No. 151, which presents recommendations and technical information on the design of structural shielding for megavoltage X and gamma-ray radiotherapy facilities. The calculations method introduced by this Report covers aspects like IMRT and other special techniques, as well as the design of structural details like doors, mazes and ducts, or the calculations of skyshine and ground shine radiation. In this work the necessary shielding for a Siemens Oncor treatment unit has been calculated, following NCRP Report No. 151 and DIN 6847-2 standard. In both cases the same isocenter workload W, use factor U, occupancy factor T and shielding design goals P, for workers and public members, are used. The results obtained with DIN 6847 are similar to the ones obtained with this Report, though there are some differences when considering the in-any-one-hour time averaged dose-equivalent rate in low occupancy factor areas, or where scattered radiation reaches the barrier under a small angle. (Author) 9 refs.

DINS measurements on VESUVIO in the Resonance Detector configuration: proton mean kinetic energy in water

Science.gov (United States)

Pietropaolo, Antonino; Andreani, Carla; Filabozzi, Alessandra; Senesi, Roberto; Gorini, Giuseppe; Perelli-Cippo, Enrico; Tardocchi, Marco; Rhodes, Nigel J.; Schooneveld, Erik M.

2006-04-01

Deep Inelastic Neutron Scattering (DINS) measurements have been performed on a liquid water sample at two different temperatures and pressures. The experiments were carried out using the VESUVIO spectrometer at the ISIS spallation neutron source. This experiment represents the first DINS measurement from water using the Resonance Detector configuration, employing yttrium-aluminum-perovskite scintillator and a 238U analyzer foil. The maximum energy of the scattered neutrons was about 70 eV, allowing to access an extended kinematic space with energy and wave vector transfers at the proton recoil peak in the range 1 eV <= hbarω <= 20 eV and 25 Å-1 <= q <= 90 Å-1, respectively. Comparison with DINS measurements on water performed in the standard Resonance Filter configuration indicates the potential advantages offered by the use of Resonance Detector approach for DINS measurements at forward scattering angles.

Dinámica de objetos transplutonianos: resultados preliminares

Science.gov (United States)

Fernández, S.; Brizuela, H.; Roig, F.; Varela, O.

Se presentan los resultados de una integración numérica de las ecuaciones de movimiento para objetos transplutonianos. Se han calculado los tiempos de Lyapunov para esos objetos y se analiza el comportamiento dinámico de los mismos.

Trayectorias evolucionistas en la dinámica de la empresa: una aproximación por dinámica de sistemas

Directory of Open Access Journals (Sweden)

Germán Eduardo Vargas

2006-05-01

Full Text Available La actividad de las firmas, como unidad socioeconómica, en el marco evolucionista está orientada integralmente por procesos de identidad, cohesión y mecanismos de adaptación y evolución; en este orden, el presente documento ilustra, a través de un modelo por dinámica de sistemas, cómo la orientación e integración estratégica basada en el conocimiento para la innovación se constituye como un imperativo de desarrollo que, a partir de un pequeño apalancamiento, permite distinguir entre dos trayectorias de evolución, a saber: firmas económicas tradicionales (inerciales, pues introducen mejoras incrementales esporádicas y modernas (dinámicas y radicalmente innovadoras, hecho a partir del cual se obtienen reveladoras conclusiones y desafíos para intervenir y adecuar el comportamiento de las empresas.2

Mutaciones dinámicas

Directory of Open Access Journals (Sweden)

Cesar A. Parra

1994-10-01

Full Text Available EI descubrimiento de repeticiones amplificadas de trinucleótidos variables en número, en pacientes con distrofia miotónica, síndrome de X-frágil, corea de Huntington y enfermedad de Kennedy, al igual que alteraciones en dinucleótidos del DNA microsatélite en pacientes con carcinoma proximal de colon, ha dado origen al concepto de mutaciones dinámicas. Esto representa una nueva avenida en teoría genética contemporánea que explica fenómenos como lo anticipación y la paradoja de Sherman que se salen del patrón mendeliano clásico.

origen e impactos de dinópolis

Directory of Open Access Journals (Sweden)

Raúl Lardiés Bosque

2005-01-01

Full Text Available El parque temático de Dinópolis se ha convertido en uno de los principales atractivos de la provincia de Teruel. Desde que el parque empezó a funcionar en junio de 2001, ya se han empezado a detectar algunos cambios de tipo socioeconómico, no sólo por el aumento del número de visitantes y turistas que llegan a la ciudad de Teruel, sino también por los impactos indirectos que esa afluencia genera en el sector turístico y comercial. En este artículo se analiza la puesta en marcha del proyecto y sus orígenes, así como la influencia socioeconómica que está teniendo a escala local. El enfoque que se ha adoptado es el de considerar a Dinópolis como una herramienta/estrategia de desarrollo local, puesto que se está convertiendo en un reclamo turístico y de visitantes para la ciudad, y porque todo ello genera impactos indirectos importantes en diversos sectores y ramas económicas.

Local copying of orthogonal entangled quantum states

International Nuclear Information System (INIS)

Anselmi, Fabio; Chefles, Anthony; Plenio, Martin B

2004-01-01

In classical information theory one can, in principle, produce a perfect copy of any input state. In quantum information theory, the no cloning theorem prohibits exact copying of non-orthogonal states. Moreover, if we wish to copy multiparticle entangled states and can perform only local operations and classical communication (LOCC), then further restrictions apply. We investigate the problem of copying orthogonal, entangled quantum states with an entangled blank state under the restriction to LOCC. Throughout, the subsystems have finite dimension D. We show that if all of the states to be copied are non-maximally entangled, then novel LOCC copying procedures based on entanglement catalysis are possible. We then study in detail the LOCC copying problem where both the blank state and at least one of the states to be copied are maximally entangled. For this to be possible, we find that all the states to be copied must be maximally entangled. We obtain a necessary and sufficient condition for LOCC copying under these conditions. For two orthogonal, maximally entangled states, we provide the general solution to this condition. We use it to show that for D = 2, 3, any pair of orthogonal, maximally entangled states can be locally copied using a maximally entangled blank state. However, we also show that for any D which is not prime, one can construct pairs of such states for which this is impossible

Dinámica de sistemas en la gestión de inventarios

Directory of Open Access Journals (Sweden)

Daniel Alejandro Agudelo Serna

2018-02-01

Full Text Available En el presente artículo se estudia el proceso de gestión de inventarios por medio de la dinámica de sistemas, como herramienta metodológica que permite conocer el comportamiento de las variables de acuerdo a sus relaciones y a las decisiones que se tomen teniendo en cuenta su causalidad y realimentación. El desarrollo del documento está determinado por una revisión de conceptos teóricos relacionados con la gestión de inventarios y dinámica de sistemas, seguido por una revisión de literatura, en donde se analizan modelos dinámicos que relacionan las variables que afectan directa o indirectamente al inventario, resaltando la importancia de modelos robustos que permitan obtener mejores resultados y así poder establecer políticas de gestión y control del inventario. El objetivo fundamental es presentar una revisión de los modelos dinámicos relacionados con el inventario, en donde es posible observar los diagramas causales y de Forrester, variables, criterios y parámetros que influyen en cada uno de los sistemas presentados. Se supone una metodología basada en la búsqueda de información, para posteriormente desarrollar un análisis detallado de cada modelo encontrado.

Una propuesta metodológica para extraer factores comunes dinámicos estacionales y no estacionarios

OpenAIRE

Orozco Sánchez, María Camila

2013-01-01

Este trabajo presenta una metodóloga empírica que permite extraer factores comunes dinámicos estacionales y no estacionarios, basados en el análisis factorial dinámico estacional de Nieto et al. (2013), en el análisis factorial dinámico de Peña y Poncela (2006) y en el modelo de estacionalidad común en diferentes frecuencias planteado por Busetti (2006). La metodología propuesta es aplicada a nueve series de la macroeconomía Colombiana

Patterns, correlates, and reduction of homework copying

Directory of Open Access Journals (Sweden)

David J. Palazzo

2010-03-01

Full Text Available Submissions to an online homework tutor were analyzed to determine whether they were copied. The fraction of copied submissions increased rapidly over the semester, as each weekly deadline approached and for problems later in each assignment. The majority of students, who copied less than 10% of their problems, worked steadily over the three days prior to the deadline, whereas repetitive copiers (those who copied >30% of their submitted problems exerted little effort early. Importantly, copying homework problems that require an analytic answer correlates with a 2(σ decline over the semester in relative score for similar problems on exams but does not significantly correlate with the amount of conceptual learning as measured by pretesting and post-testing. An anonymous survey containing questions used in many previous studies of self-reported academic dishonesty showed ∼1/3 less copying than actually was detected. The observed patterns of copying, free response questions on the survey, and interview data suggest that time pressure on students who do not start their homework in a timely fashion is the proximate cause of copying. Several measures of initial ability in math or physics correlated with copying weakly or not at all. Changes in course format and instructional practices that previous self-reported academic dishonesty surveys and/or the observed copying patterns suggested would reduce copying have been accompanied by more than a factor of 4 reduction of copying from ∼11% of all electronic problems to less than 3%. As expected (since repetitive copiers have approximately three times the chance of failing, this was accompanied by a reduction in the overall course failure rate. Survey results indicate that students copy almost twice as much written homework as online homework and show that students nationally admit to more academic dishonesty than MIT students.

Evaluation and Comparison of the Effects of RRA, T73 and T6 Heat Treatments on Hardness, Tensile and Bending Strengths of 7075 Aluminum Alloy

Directory of Open Access Journals (Sweden)

M. Assadi

2016-09-01

20 min and in the third stage aging process was repeated like T6 treatment. Evaluation of the microstructures and fractured surfaces were performed with optical microscopes (OM and scanning electron microscopes (SEM. Energy dispersive spectroscopy (EDS was used to study the chemical composition of precipitates. Hardness, tensile and bending strength were evaluated according to ASTM E384-11e1, ASTM B557-06 and DIN 50121 standards. RRA treatment increased tensile strength from 466 to 485 MPa and hardness from 110 to 165 Vickers. After T6 treatment, tensile strength increased from 466 to 505 MPa and hardness from 110 to 160 Vickers. In T73 process, the tensile strength remained almost constant (465 MPa but yield strength increased from 394 to 410 MPa and hardness decreased from 110 to 84 Vickers. The bending strength increased from 797 to 844, 920 and 1030 MPa in T73, RRA and T6 processes, respectively. By applying RRA process in optimized temperature and time, hardness, tensile and bending strengths of 7075 aluminum alloy were enhanced from 5 to 15% compared to that of T6 and T73 processes.

The DinB•RecA complex of Escherichia coli mediates an efficient and high-fidelity response to ubiquitous alkylation lesions.

Science.gov (United States)

Cafarelli, Tiziana M; Rands, Thomas J; Godoy, Veronica G

2014-03-01

Alkylation DNA lesions are ubiquitous, and result from normal cellular metabolism as well as from treatment with methylating agents and chemotherapeutics. DNA damage tolerance by translesion synthesis DNA polymerases has an important role in cellular resistance to alkylating agents. However, it is not yet known whether Escherichia coli (E. coli) DNA Pol IV (DinB) alkylation lesion bypass efficiency and fidelity in vitro are similar to those inferred by genetic analyses. We hypothesized that DinB-mediated bypass of 3-deaza-3-methyladenine, a stable analog of 3-methyladenine, the primary replication fork-stalling alkylation lesion, would be of high fidelity. We performed here the first kinetic analyses of E. coli DinB•RecA binary complexes. Whether alone or in a binary complex, DinB inserted the correct deoxyribonucleoside triphosphate (dNTP) opposite either lesion-containing or undamaged template; the incorporation of other dNTPs was largely inefficient. DinB prefers undamaged DNA, but the DinB•RecA binary complex increases its catalytic efficiency on lesion-containing template, perhaps as part of a regulatory mechanism to better respond to alkylation damage. Notably, we find that a DinB derivative with enhanced affinity for RecA, either alone or in a binary complex, is less efficient and has a lower fidelity than DinB or DinB•RecA. This finding contrasts our previous genetic analyses. Therefore, mutagenesis resulting from alkylation lesions is likely limited in cells by the activity of DinB•RecA. These two highly conserved proteins play an important role in maintaining genomic stability when cells are faced with ubiquitous DNA damage. Kinetic analyses are important to gain insights into the mechanism(s) regulating TLS DNA polymerases. Copyright © 2013 Wiley Periodicals, Inc.

Estudio dinámico de un potencial perturbador dependiente de dos parámetros

Science.gov (United States)

Miloni, O.; Brunini, A.

El objeto del presente trabajo consiste en el estudio dinámico de un sistema dinámico caracterizado por la función hamiltoniana correspondiente a un satélite planetario perturbado por la acción del Sol y del achatamiento del planeta madre. Cuando dicha Hamiltoniana se promedia respecto de los términos de corto período, esta queda con dos grados de libertad, y su estudio puede ser realizado con las herramientas clásicas de la dinámica no-lineal. Se tratará de determinar regiones regulares y caóticas de movimiento. En el caso de estas últimas, es de particular interés la determinación de su orígen.

Regulated expression of the dinR and recA genes during competence development and SOS induction in Bacillus subtilis

NARCIS (Netherlands)

Haijema, BJ; vanSinderen, D; Winterling, K; Kooistra, J; Venema, G; Hamoen, LW

1996-01-01

It has been hypothesized that the dinR gene product of Bacillus subtilis acts as a repressor of the SOS regulon by binding to DNA sequences located upstream of SOS genes, including dinR and recA. Following activation as a result of DNA damage, RecA is believed to catalyse DinR-autocleavage, thus

Dynamics in copy numbers of five plasmids of a dairy Lactococcus lactis in dairy-related conditions including near-zero growth rates.

Science.gov (United States)

van Mastrigt, Oscar; Lommers, Marcel M A N; de Vries, Yorick C; Abee, Tjakko; Smid, Eddy J

2018-03-23

Lactic acid bacteria can carry multiple plasmids affecting their performance in dairy fermentations. The expression of plasmid-encoded genes and the activity of the corresponding proteins is severely affected by changes in the number of plasmid copies. We studied the impact of growth rate on dynamics of plasmid copy numbers at high growth rates in chemostat cultures and down to near-zero growth rates in retentostat cultures. Five plasmids of the dairy strain Lactococcus lactis FM03-V1 were selected which varied in size (3 to 39 kb), in replication mechanism (theta or rolling-circle) and in putative (dairy-associated) functions. Copy numbers ranged from 1.5 to 40.5 and the copy number of theta-type replicating plasmids were negatively correlated to the plasmid size. Despite the extremely wide range of growth rates (0.0003 h -1 to 0.6 h -1 ), copy numbers of the five plasmids were stable and only slightly increased at near-zero growth rates showing that the plasmid replication rate was strictly controlled. One low-copy number plasmid, carrying a large exopolysaccharide gene cluster, was segregationally unstable during retentostat cultivations reflected in complete loss of the plasmid in one of the retentostat cultures. The copy number of the five plasmids was also hardly affected by varying the pH value, nutrient limitation or presence of citrate (maximum 2.2-fold) signifying the stability in copy number of the plasmids. Importance Lactococcus lactis is extensively used in starter cultures for dairy fermentations. Important traits for growth and survival of L. lactis in dairy fermentations are encoded by genes located on plasmids, such as genes involved in lactose and citrate metabolism, protein degradation and oligopeptide uptake and bacteriophage resistance. Because the number of plasmid copies could affect the expression of plasmid-encoded genes, it is important to know the factors that influence the plasmid copy numbers. We monitored plasmid copy numbers of L

Effects of different N sources on riverine DIN export and retention in a subtropical high-standing island, Taiwan

Science.gov (United States)

Huang-Chuan, Jr.; Lee, Tsung-Yu; Lin, Teng-Chiu; Hein, Thomas; Lee, Li-Chin; Shih, Yu-Ting; Kao, Shuh-Ji; Shiah, Fuh-Kwo; Lin, Neng-Huei

2016-03-01

Increases in nitrogen (N) availability and mobility resulting from anthropogenic activities have substantially altered the N cycle, both locally and globally. Taiwan characterized by the subtropical montane landscape with abundant rainfall, downwind of the most rapidly industrializing eastern coast of China, can be a demonstration site for extremely high N input and riverine DIN (dissolved inorganic N) export. We used 49 watersheds with similar climatic and landscape settings but classified into low, moderate, and highly disturbed categories based on population density to illustrate their differences in nitrogen inputs (through atmospheric N deposition, synthetic fertilizers, and human emission) and DIN export ratios. Our results showed that the island-wide average riverine DIN export is ˜ 3800 kg N km-2 yr-1, approximately 18 times the global average. The average riverine DIN export ratios are 0.30-0.51, which are much higher than the averages of 0.20-0.25 of large rivers around the world, indicating excessive N input relative to ecosystem demand or retention capacity. The low disturbed watersheds have a high N retention capacity and DIN export ratios of 0.06-0.18 in spite of the high N input (˜ 4900 kg N km-2 yr-1). The high retention capacity is likely due to effective uptake by secondary forests in the watersheds. The moderately disturbed watersheds show a linear increase in DIN export with increases in total N inputs and mean DIN export ratios of 0.20 to 0.31. The main difference in land use between low and moderately disturbed watersheds is the greater proportion of agricultural land cover in the moderately disturbed watersheds. Thus, their greater DIN export could be attributed to N fertilizers used in the agricultural lands. The greater export ratios also imply that agricultural lands have a lower proportional N retention capacity and that reforestation could be an effective land management practice to reduce riverine DIN export. The export ratios of the

Multiple-copy entanglement transformation and entanglement catalysis

International Nuclear Information System (INIS)

Duan Runyao; Feng Yuan; Li Xin; Ying Mingsheng

2005-01-01

We prove that any multiple-copy entanglement transformation [S. Bandyopadhyay, V. Roychowdhury, and U. Sen, Phys. Rev. A 65, 052315 (2002)] can be implemented by a suitable entanglement-assisted local transformation [D. Jonathan and M. B. Plenio, Phys. Rev. Lett. 83, 3566 (1999)]. Furthermore, we show that the combination of multiple-copy entanglement transformation and the entanglement-assisted one is still equivalent to the pure entanglement-assisted one. The mathematical structure of multiple-copy entanglement transformations then is carefully investigated. Many interesting properties of multiple-copy entanglement transformations are presented, which exactly coincide with those satisfied by the entanglement-assisted ones. Most interestingly, we show that an arbitrarily large number of copies of state should be considered in multiple-copy entanglement transformations

Mand træn din bækkenbund og få bedre rejsning

DEFF Research Database (Denmark)

Ravnkilde Marlet, Laila; Gerbild, Helle Nygaard

2016-01-01

Har du (eller din mand) problemer med at holde på urin eller at opnå eller bevare rejsningen, er der god grund til at søge hjælp. Der findes nemlig effektive og billige behandlingsmuligheder.......Har du (eller din mand) problemer med at holde på urin eller at opnå eller bevare rejsningen, er der god grund til at søge hjælp. Der findes nemlig effektive og billige behandlingsmuligheder....

Análise do comportamento dinâmico em pontes pedonais

OpenAIRE

Valentim, Nilton Leonardo

2012-01-01

Dissertação para obtenção do Grau de Mestre em Engenharia Civil - Perfil Estruturas A análise do comportamento dinâmico de estruturas de engenharia civil tem um interesse evidente para a avaliação dos efeitos das acções de sismos, vento e tráfego ferroviário, rodoviário ou pedonal. O interesse desta avaliação estende-se também à própria caracterização global do estado das estruturas, uma vez que as propriedades dinâmicas estão directamente relacionadas com esse estado. Pa...

X-ray protective clothing. Does DIN 6857-1 allow an objective comparison between lead-free and lead-composite materials?

International Nuclear Information System (INIS)

Eder, H.; Schlattl, H.; Hoeschen, C.

2010-01-01

Purpose: The validity of DIN 6857-1 to establish lead equivalence for protective clothing is evaluated by Monte Carlo simulations and measurements. Materials and Methods: Commercially available protective clothing made of lead, lead-free and lead-composite materials has been tested regarding its protective efficacy. The analysis has been performed on the one hand in accordance with the test conditions described in the manufacturing standard DIN EN 61331-3 and on the other hand following the new DIN 6857-1 standard. Additionally, measurements have been carried out under simulated patient conditions by using an Alderson-Rando phantom. Results: Following DIN EN 61331-3, the lead-free protective clothing achieved the required protective efficacy only at a restricted tube-voltage range. The test according to DIN 6857-1 showed that the protective criteria were fulfilled only by one lead-composite apron, but not by the three lead-free aprons examined. Thus, in order to guarantee the same protection as lead between 50 and 120 kV, the conditions of DIN 6857-1 must be fulfilled. Conclusion: A modification of DIN EN 61331-3 to account for secondary radiation is strongly advised in the case of lead-free materials. In summary, most of the protective lead-free aprons in use should be used with care, particularly for examinations with a high dose. (orig.)

Un modelo de sistema dinámico híbrido utilizando el enfoque de la lógica difusa

Directory of Open Access Journals (Sweden)

Germán García Benítez

2010-01-01

Full Text Available Se presenta un modelo de sistema dinámico híbrido utilizando la lógica difusa. Para lograr esto se hace una breve descripción de los principales enfoques que se tienen en la actualidad de los sistemas dinámicos híbridos desarrollando las ecuaciones básicas de los bloques que conforman el modelo. Actualmente la teoría del control se ha centrado en el estudio por separado de la dinámica continua y la dinámica discreta; sin embargo, es necesario introducir el estudio de la combinación de ambos en un solo tratado. En el ámbito industrial los procesos son dinámicos y toda su estructura de control está basada en la teoría de la lógica digital. Sin embargo existe el paradigma de la lógica difusa, la cual se introduce en este artículo para proponer un nuevo enfoque. Cabe mencionar que para validar el modelo se utilizan herramientas computacionales de simulación de sistemas dinámicos.

Explanations on nomenclature and number of material for steels in accordance with DIN norm - (Deutsch Industrie Norm)

International Nuclear Information System (INIS)

Barone, S.D.; Silva, T.C.V. da; Bittencourt, M.S.Q.

1980-01-01

The materials specified by DIN norm are identified by its nomenclature and corresponding DIN number. The characters (numbers and letters) aim to classify the material and provide indication on main alloy properties and elements. (M.C.K.) [pt

Nuevos modelos de redes de neuronas artificiales para simulación y control desistemas dinámicos

OpenAIRE

Galván León, Inés María

1997-01-01

Uno de los principales problemas en el campo de los procesos dinámicos es el control de su comportamiento, control que es necesario para que la evolución del proceso se lleve a cabo en una dirección y con una cierta dinámica deseada. Esto puede traducirse en mantener una condición estable, seguir una trayectoria especificada o alcanzar una determinada meta. Para ello es necesario incluir un sistema de control, el cual influye en la dinámica del proceso, regulando su comportamiento. La teoría...

[Ernst Rüdin--a Swiss psychiatrist as the leader of Nazi psychiatry--the final solution as a goal].

Science.gov (United States)

Peters, U H

1996-09-01

The study of work and life of the Swiss-German psychiatrist Ernst Rüdin, honoured up to our time as "father of psychiatric genealogy", lead to different views. Rüdin early in his life became a racial fanatic, and as a propagandist for the purity of the "Germanic people" he constantly demanded preventive coercive measures against the reproduction of the mentally ill and other, in the racist's view, undesirable persons. With this objective in mind he started his psychiatric research. The results of Rüdin's monograph about the genetics of dementia precox do not withstand scientific criticism but confirmed his preexisting opinions. They served however as scientific reasoning for the forced sterilisation by the Nazis, for which Rüdin's comments were obligatory. The next step, to the holocaust of the mentally ill and the undesirable, was not only tacitly agreed with by Rüdin. Max Weber, Karl Jaspers and others realised at an early time the dangers arising from racial hygienics and voiced their warnings in a plain language. The surviving victims are still waiting for compensation.

[Automated measurement of distance vision based on the DIN strategy].

Science.gov (United States)

Effert, R; Steinmetz, H; Jansen, W; Rau, G; Reim, M

1989-07-01

A method for automated measurement of far vision is described which meets the test requirements laid down in the new DIN standards. The subject sits 5 m from a high-resolution monitor on which either Landolt rings or Snellen's types are generated by a computer. By moving a joystick the subject indicates to the computer whether he can see the critical detail (e.g., the direction of opening of the Landolt ring). Depending on the subject's input and the course of the test so far, the computer generates the next test symbol until the threshold criterion is reached. The sequence of presentation of the symbols and the threshold criterion are also in accordance with the DIN standard. Initial measurements of far vision using this automated system produced similar results to those obtained by conventional methods.

Inferring species trees from incongruent multi-copy gene trees using the Robinson-Foulds distance

Science.gov (United States)

2013-01-01

Background Constructing species trees from multi-copy gene trees remains a challenging problem in phylogenetics. One difficulty is that the underlying genes can be incongruent due to evolutionary processes such as gene duplication and loss, deep coalescence, or lateral gene transfer. Gene tree estimation errors may further exacerbate the difficulties of species tree estimation. Results We present a new approach for inferring species trees from incongruent multi-copy gene trees that is based on a generalization of the Robinson-Foulds (RF) distance measure to multi-labeled trees (mul-trees). We prove that it is NP-hard to compute the RF distance between two mul-trees; however, it is easy to calculate this distance between a mul-tree and a singly-labeled species tree. Motivated by this, we formulate the RF problem for mul-trees (MulRF) as follows: Given a collection of multi-copy gene trees, find a singly-labeled species tree that minimizes the total RF distance from the input mul-trees. We develop and implement a fast SPR-based heuristic algorithm for the NP-hard MulRF problem. We compare the performance of the MulRF method (available at http://genome.cs.iastate.edu/CBL/MulRF/) with several gene tree parsimony approaches using gene tree simulations that incorporate gene tree error, gene duplications and losses, and/or lateral transfer. The MulRF method produces more accurate species trees than gene tree parsimony approaches. We also demonstrate that the MulRF method infers in minutes a credible plant species tree from a collection of nearly 2,000 gene trees. Conclusions Our new phylogenetic inference method, based on a generalized RF distance, makes it possible to quickly estimate species trees from large genomic data sets. Since the MulRF method, unlike gene tree parsimony, is based on a generic tree distance measure, it is appealing for analyses of genomic data sets, in which many processes such as deep coalescence, recombination, gene duplication and losses as

Insuficiencia dinámica, crecimiento y desempleo en México, 1974-2012

OpenAIRE

Blanca L. Avendaño Vargas; Ignacio Perrotini Hernández

2015-01-01

El artículo presenta una reformulación de la hipótesis de insuficiencia dinámica de Prebisch (1970), analiza la teoría dinámica de Harrod (1939), la ley Kaldor-Verdoorn (Kaldor, 1966; 1967) y la teoría del crecimiento endógeno de Thirlwall (1969; 2000). A posterioriestudiamos los determinantes del crecimiento económico y del desempleo en México durante el periodo 1974-2012. Con base en el análisis empírico, sostenemos que una baja tasa de acumulación genera una reducida absorción de empleo, u...

Dinámica de sistemas en la gestión de inventarios

OpenAIRE

Daniel Alejandro Agudelo Serna; Yohana Marcela López Rivera

2018-01-01

En el presente artículo se estudia el proceso de gestión de inventarios por medio de la dinámica de sistemas, como herramienta metodológica que permite conocer el comportamiento de las variables de acuerdo a sus relaciones y a las decisiones que se tomen teniendo en cuenta su causalidad y realimentación. El desarrollo del documento está determinado por una revisión de conceptos teóricos relacionados con la gestión de inventarios y dinámica de sistemas, seguido por una revisión de lit...

Dinámica migratoria... ¿hibridación cultural u homologación global?

Directory of Open Access Journals (Sweden)

Claudia Carolina Zamorano Villarreal

2014-01-01

Full Text Available Ante la consolidación del modelo de subcontratación en México asistimos a una nueva cultura laboral ¿Qué cambios ha impulsado este modelo en las prácticas de la pobla - ción y su cultura? Analizando la relación entre el modo de producción flexible de la maquila y la dinámica de migración propia a las ciudades de la frontera norte de Mé - xico, se muestra que la maquiladora respetó y aprovechó está dinámica para reducir o aumentar el número de trabajadores, según lo requiriera la producción flexible. Pero, desde mediados de los años noventa, empezó a transformar estás dinámicas y con ellas, la cultura de sus trabajadores.

Copy Counts

Science.gov (United States)

Beaumont, Lee R.

1970-01-01

The level of difficulty of straight copy, which is used to measure typewriting speed, is influenced by syllable intensity (the average number of syllables per word), stroke intensity (average number of strokes per word), and high-frequency words. (CH)

Welding of Low Alloy Steel DIN 15Mo3 by MIG/MAG Spot

OpenAIRE

Nabeel K. Abid Al- Sahib

2006-01-01

????? ????? ????? ????? ??????? ?????? ?? ????? ?????? ?????? ?????? ??????? ?????? ?????? (MIG/MAG spot) ???????? ??? ??????? ????? ?? ???? ???????? ????? ??? ???????? ?? ?????? ??????????? ??????? ???????? ????? ???? ??????? ??????? ????? ??? (DIN15Mo3) ?????? ?????? ?????? ?????? ?????? ?? ???? ???? ?????? ???????" ??? ?????? ??? ????. ????? ??????? ??????? ?????? ??? CO2 ????" ?? ??? ??????? ?? ???? ??????? ??????? ????? ?? ?????? ????? ?? ??? ???? ?? ????? (13%) ???? (4mm) ???? (2sec). ?...

Effects of different N sources on riverine DIN export and retention in subtropical high-standing island, Taiwan

Science.gov (United States)

Huang, J.-C.; Lee, T.-Y.; Lin, T.-C.; Hein, T.; Lee, L.-C.; Shih, Y.-T.; Kao, S.-J.; Shiah, F.-K.; Lin, N.-H.

2015-10-01

Increases in nitrogen (N) availability and mobility resulting from anthropogenic activities has substantially altered N cycle both locally and globally. Taiwan characterized by the subtropical montane landscape with abundant rainfall, downwind to the most rapidly industrializing east coast of China can be a demonstration site for extreme high N input and riverine DIN (dissolved inorganic N) export. We used 49 watersheds classified into low-, moderate-, and highly-disturbed categories based on population density to illustrate their differences in nitrogen inputs through atmospheric N deposition, synthetic fertilizers and human emission and DIN export ratios. Our results showed that the island-wide average riverine DIN export is ~ 3800 kg N km-2 yr-1, approximately 18-fold higher than the global average mostly due to the large input of synthetic fertilizers. The average riverine DIN export ratio is 0.30-0.51, which is much higher than the average of 0.20-0.25 of large rivers around the world indicating excessive N input relative to ecosystem demand or retention capacity. The low-disturbed watersheds, despite of high N input, only export 0.06-0.18 of the input so were well buffered to changes in input quantity suggesting high efficiency of nitrogen usage or high N retention capacity of the less disturbed watersheds. The high retention capacity probably is due to the effective uptake by secondary forests in the watersheds. The moderate-disturbed watersheds show a linear increase of output with increases in total N inputs and a mean DIN export ratio of 0.20 to 0.31. The main difference in land use between low and moderately disturbed watershed is the relative proportions of agricultural land and forests, not the built-up lands. Thus, their greater DIN export quantity could be attributed to N fertilizers used in the agricultural lands. The greater export ratios also imply that agricultural lands have lower proportional N retention capacity and that reforestation could be

Establishment of Wear Resistant HVOF Coatings for 50CrMo4 Chromium Molybdenum Alloy Steel as an Alternative for Hard Chrome Plating

Science.gov (United States)

Karuppasamy, S.; Sivan, V.; Natarajan, S.; Kumaresh Babu, S. P.; Duraiselvam, M.; Dhanuskodi, R.

2018-05-01

High cost imported components of seamless steel tube manufacturing plants wear frequently and need replacement to ensure the quality of the product. Hard chrome plating, which is time consuming and hazardous, is conventionally used to restore the original dimension of the worn-out surface of the machine components. High Velocity Oxy-Fuel (HVOF) thermal spray coatings with NiCrBSi super alloy powder and Cr3C2 NiCr75/25 alloy powder applied on a 50CrMo4 (DIN-1.7228) chromium molybdenum alloy steel, the material of the wear prone machine component, were evaluated for use as an alternative for hard chrome plating in this present work. The coating characteristics are evaluated using abrasive wear test, sliding wear test and microscopic analysis, hardness test, etc. The study results revealed that the HVOF based NiCrBSi and Cr3C2NiCr75/25 coatings have hardness in the range of 800-900 HV0.3, sliding wear rate in the range of 50-60 µm and surface finish around 5 microns. Cr3C2 NiCr75/25 coating is observed to be a better option out of the two coatings evaluated for the selected application.

Estabilizações lombares dinâmicas Estabilizaciones lumbares dinámicas Lumbar dynamic stabilizations

Directory of Open Access Journals (Sweden)

Ivan Dias Rocha

2012-01-01

Full Text Available O funcionamento fisiológico normal da coluna depende da movimentação normal de cada unidade motora, que consiste em duas vértebras e o disco intervertebral interposto entre elas. Embora a artrodese da coluna vertebral venha sendo utilizada para o tratamento de diversas doenças da coluna, essa modalidade de tratamento acarreta a perda de movimentação dos níveis em que houve a fusão e como consequência pode sobrecarregar os níveis adjacentes podendo provocar a sua degeneração precoce. Proponentes das técnicas de estabilização dinâmicas acreditam que estas podem levar a correção dos problemas minimizando o risco de degeneração dos níveis adjacentes. Atualmente existem no mercado diversos métodos de estabilização dinâmica anteriores e posteriores. Já existem trabalhos biomecânicos que comprovam o benefício teórico de quase todos eles, porém ainda hoje, faltam ensaios clínicos que comprovem a sua utilidade e segurança por longos períodos de seguimento para o paciente. Portanto é fundamental que estes materiais sejam analisados de maneira acadêmica para que no futuro próximo possam ser utilizados em situações precisas e com segurança para os pacientes.El funcionamiento fisiológico normal de la columna depende de los movimientos normales de cada unidad motora, la cual consiste de dos vértebras y del disco intervertebral interpuesto entre ellas. Aunque la artrodesis de la columna vertebral está siendo utilizada para el tratamiento de diversas enfermedades de la columna, esa modalidad de tratamiento causa la pérdida de los movimientos en los niveles en los que hubo la fusión y, como consecuencia, puede sobrecargar los niveles adyacentes, pudiendo provocar su degeneración precoz. Los proponentes de las técnicas de estabilización dinámica creen que éstas pueden llevar a la corrección de los problemas, minimizando el riesgo de degeneración de los niveles adyacentes. Actualmente, existen en el mercado

Sistemas dinámicos en la interacción emocional madre-hijo: primera fase

Directory of Open Access Journals (Sweden)

Jaime Castro Martínez

2013-03-01

Full Text Available Los avances en psicología de las emociones y psicología del desarrollo han exigido nuevos cambios tanto de orden teórico como metodológico para describir y explicar la variabilidad de las res-puestas infantiles a los cambios que tienen lugar en la dinámica socio-emocional con la madre. Producto de estas variaciones, aparece la integración de los sistemas dinámicos a las descrip- ciones de los teóricos del desarrollo emocional bajo supuestos psicobiológicos y sociobiológicos. Esta investigación indaga el posible uso de modelos de sistemas dinámicos en la generación de patrones de organización durante la interrelación socio- emocional madre-hijo, bajo cambios en los estados emocionales de la madre y bajo modificaciones debidas al desarrollo infantil. Los hallazgos de esta primera fase muestran algunas diferencias en las dinámicas socio-emocionales en cada uno de los estados emocionales maternos, al igual que regu- laridades en la variación por estado emocional. La investigación sugiere ampliar el marco teórico hacia modelos de componentes emocionales y modelos neurobiológicos, y la inclusión de modelos matemáticos de predicción y de análisis de series de tiempos.

36 CFR 1290.6 - Originals and copies.

Science.gov (United States)

2010-07-01

... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Originals and copies. 1290.6... ASSASSINATION RECORDS COLLECTION ACT OF 1992 (JFK ACT) § 1290.6 Originals and copies. (a) For purposes of determining whether originals or copies of assassination records will be made part of the President John F...

Preservation Copying Endangered Historic Negative Collections

DEFF Research Database (Denmark)

Kejser, Ulla Bøgvad

2008-01-01

This article discusses preservation copying of unstable B&W nitrate and acetate still photographic negatives. It focuses on evaluating two different strategies for preserving the copies from a point of view of quality and cost-effectiveness. The evaluated strategies are preservation of the master...... by describing essential characteristics of negatives, which must be passed on to the copies, and the required metadata and technical imaging specifications. Next the paper discusses strategies for preservation and makes an analysis with the LIFE2 Costing Model. The paper concludes that the most beneficial...... and cost-effective preservation solution for large format negatives is to keep the preservation copies as digital files. However, it also acknowledges that it is important to revisit such strategies regularly to monitor changes in user expectations, technologies and costs....

COPI is required for enterovirus 71 replication.

Directory of Open Access Journals (Sweden)

Jianmin Wang

Full Text Available Enterovirus 71 (EV71, a member of the Picornaviridae family, is found in Asian countries where it causes a wide range of human diseases. No effective therapy is available for the treatment of these infections. Picornaviruses undergo RNA replication in association with membranes of infected cells. COPI and COPII have been shown to be involved in the formation of picornavirus-induced vesicles. Replication of several picornaviruses, including poliovirus and Echovirus 11 (EV11, is dependent on COPI or COPII. Here, we report that COPI, but not COPII, is required for EV71 replication. Replication of EV71 was inhibited by brefeldin A and golgicide A, inhibitors of COPI activity. Furthermore, we found EV71 2C protein interacted with COPI subunits by co-immunoprecipitation and GST pull-down assay, indicating that COPI coatomer might be directed to the viral replication complex through viral 2C protein. Additionally, because the pathway is conserved among different species of enteroviruses, it may represent a novel target for antiviral therapies.

Copy-Editing: The Cambridge Handbook.

Science.gov (United States)

Butcher, Judith

This handbook is designed as a reference manual for copy editors who prepare typescript for printing. It deals with the following topics: the copy editor's function; the work to be done at each stage in the production process; some difficult points of spelling, capitalization, and other features collectively known as "house style"; the parts of a…

Single-copy insertion of transgenes in Caenorhabditis elegans

DEFF Research Database (Denmark)

Frøkjaer-Jensen, Christian; Davis, M Wayne; Hopkins, Christopher E

2008-01-01

developed a method that inserts a single copy of a transgene into a defined site. Mobilization of a Mos1 transposon generates a double-strand break in noncoding DNA. The break is repaired by copying DNA from an extrachromosomal template into the chromosomal site. Homozygous single-copy insertions can...... be obtained in less than 2 weeks by injecting approximately 20 worms. We have successfully inserted transgenes as long as 9 kb and verified that single copies are inserted at the targeted site. Single-copy transgenes are expressed at endogenous levels and can be expressed in the female and male germlines....

“We’re Still in a Struggle”: Diné Resilience, Survival, Historical Trauma, and Healing

OpenAIRE

Goodkind, Jessica R.; Hess, Julia Meredith; Gorman, Beverly; Parker, Danielle P.

2012-01-01

As part of a community/university collaborative effort to promote the mental health and well-being of Diné (Navajo) youth, we explored the relevance of addressing historical trauma and current structural stressors and of building on individual and community strengths through healing and social transformation at multiple levels. Qualitative analyses of 74 ethnographic interviews with 37 Diné youth, parents, and grandparents suggested that a focus on historical trauma as a conceptual frame for ...

[Reform of the Law DIN EN ISO 9001:2000. Commentary on the new requirements on quality management systems].

Science.gov (United States)

Eckert, H; Böhmer, K

2000-09-01

Since January this year the German translation of the third draft to the reform of the DIN EN ISO 9000 is available. The draft reveals an approximation to the models of Business Excellence. Most important changes are a far stronger customer orientation, orientation on the processes and resource management. The norms DIN EN ISO 9002 and 9003 have been removed, ISO 8402 has been integrated in the reformed DIN EN ISO 9000. Apart from that the compatibility with other management systems has been improved. It was the aim of the reform to improve the applicability for all types of business, products and services.

Dinámica exportadora de las empresas born global en Colombia

Directory of Open Access Journals (Sweden)

Diana Marcela Escandón Barbosa

2015-11-01

Full Text Available Este artículo pretende analizar las condiciones principales del mercado exportador de las empresas born global en el caso colombiano, teniendo en cuenta los principales factores del entorno que determinan su dinámica exportadora. Se utiliza la base de datos GEM Colombia del año 2011, para analizar 297 empresas born global colombianas, mediante un análisis descriptivo y la estimación de un modelo de conglomerados bietápico. Los resultados muestran que los cambios tecnológicos, las características sectoriales y la intensidad competitiva son factores determinantes de la dinámica exportadora de las empresas born global en Colombia, y se concluye que los empresarios se adaptan al mercado internacional mejorando continuamente sus productos y procesos.

A new implementation of full resolution SBAS-DInSAR processing chain for the effective monitoring of structures and infrastructures

Science.gov (United States)

Bonano, Manuela; Buonanno, Sabatino; Ojha, Chandrakanta; Berardino, Paolo; Lanari, Riccardo; Zeni, Giovanni; Manunta, Michele

2017-04-01

The advanced DInSAR technique referred to as Small BAseline Subset (SBAS) algorithm has already largely demonstrated its effectiveness to carry out multi-scale and multi-platform surface deformation analyses relevant to both natural and man-made hazards. Thanks to its capability to generate displacement maps and long-term deformation time series at both regional (low resolution analysis) and local (full resolution analysis) spatial scales, it allows to get more insights on the spatial and temporal patterns of localized displacements relevant to single buildings and infrastructures over extended urban areas, with a key role in supporting risk mitigation and preservation activities. The extensive application of the multi-scale SBAS-DInSAR approach in many scientific contexts has gone hand in hand with new SAR satellite mission development, characterized by different frequency bands, spatial resolution, revisit times and ground coverage. This brought to the generation of huge DInSAR data stacks to be efficiently handled, processed and archived, with a strong impact on both the data storage and the computational requirements needed for generating the full resolution SBAS-DInSAR results. Accordingly, innovative and effective solutions for the automatic processing of massive SAR data archives and for the operational management of the derived SBAS-DInSAR products need to be designed and implemented, by exploiting the high efficiency (in terms of portability, scalability and computing performances) of the new ICT methodologies. In this work, we present a novel parallel implementation of the full resolution SBAS-DInSAR processing chain, aimed at investigating localized displacements affecting single buildings and infrastructures relevant to very large urban areas, relying on different granularity level parallelization strategies. The image granularity level is applied in most steps of the SBAS-DInSAR processing chain and exploits the multiprocessor systems with distributed

DNA-damage-inducible (din) loci are transcriptionally activated in competent Bacillus subtilis

International Nuclear Information System (INIS)

Love, P.E.; Lyle, M.J.; Yasbin, R.E.

1985-01-01

DNA damage-inducible (din) operon fusions were generated in Bacillus subtilis by transpositional mutagenesis. These YB886(din::Tn917-lacZ) fusion isolates produced increased β-galactosidase when exposed to mitomycin C, UV radiation, or ethyl methanesulfonate, indicating that the lacZ structural gene had inserted into host transcriptional units that are induced by a variety of DNA-damaging agents. One of the fusion strains was DNA-repair deficient and phenotypically resembled a UV-sensitive mutant of B. subtilis. Induction of β-galactosidase also occurred in the competent subpopulation of each of the din fusion strains, independent of exposure to DNA-damaging agents. Both the DNA-damage-inducible and competence-inducible components of β-galactosidase expression were abolished by the recE4 mutation, which inhibits SOS-like (SOB) induction but does not interfere with the development of the component state. The results indicate that gene expression is stimulated at specific loci within the B. subtilis chromosome both by DNA-damaging agents and by the development of competence and that this response is under the control of the SOB regulatory system. Furthermore, they demonstrate that at the molecular level SOB induction and the development of competence are interrelated cellular events

Dinâmica molecular ab initio:aplicações ao estudo de propriedades electrónicas de sistemas moleculares

OpenAIRE

Martiniano, Hugo Filipe de Mesquita Costa, 1978-

2013-01-01

Tese de doutoramento, Química (Química-Física), Universidade de Lisboa, Faculdade de Ciências, 2013 O método da dinâmica molecular ab initio exibe vantagens significativas para o estudo da estrutura e propriedades electrónicas de sistemas moleculares complexos. No entanto, uma das suas desvantagens é o elevado custo computacional, quando comparado com os métodos de dinâmica molecular clássicos. Um dos modos de resolver este problema é adoptar uma abordagem sequencial, na qual a dinâmica é ...

Innovations in the Poetry Form by Sheikh Sa'd od-Din Ahmad Ansari

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Najaf Jowkar

2016-05-01

Full Text Available AbstractSheikh Sa'd od-Din Ahmad َ Ansari, the son of Mawlana Abd ol-Ghaffar Ibn Abd ol-Karim, is a mystic of the 12th and 13th centuries AH. Sa'd od-Din was born in Kabul in the village called Yahya Yahyaee in 1140 AH and died in the same place in 1225 AH (Ansari, 1374: 6. In his youth, he learned canonical law and theology from his father but was soon attracted to mysticism (Heravi, 1373, 43. After performing Hajj in between the years 1169-113 AH and getting permission to guide people from Naqshbandiyeh and Qaderiyeh mystic Sheikh Mohammad Saman Madani, he returned home and guided people untill the end of his life (Ansari, 1390: 3. Sheikh Sa'd od-Din was well learned in Islamic studies, Arabic language, rhetoric and sciences of his time. He was also familiar with the works of poets such as 'Attar, Rumi, Hafez, Ibn Arabi and other great names of mysticism. He was attached to Rumi and Hafez and has quoted them frequently in his works.Sheikh Sa'd od-Din wrote thirty six books and treatises including seven Divans and two Masnavis in Persian; He also wrote a book entitled The Mine of Unity and treatises  such as "Greetings Noble Tatar", "Habl ol-Matin" and "The Elite" in Arabic. He composed some poems in Arabic as well.At least from 1174 AH Sheikh Sa'd od-Din started to bring changes to the ancient Persian poetry; thus his deconstruction made poetical form much similar to contemporary Persian poetry. However, due to political and cultural distance between Iran and Afghanistan, we did not have a chance to get familiar with his innovations.His innovations consist of the following:1.      Refrained Masnavi (masnavi tarjee'band: He changed masnavi in a way that we can call it refrained masnavi, a sample of which is included in the paper. It consists of fifteen stanzas: The first stanza with eight lines, the second stanza fifty four lines, the twelfth stanza eleven lines and the other stanzas having equal lines. The line between

Revisiting the definition of local hardness and hardness kernel.

Science.gov (United States)

Polanco-Ramírez, Carlos A; Franco-Pérez, Marco; Carmona-Espíndola, Javier; Gázquez, José L; Ayers, Paul W

2017-05-17

An analysis of the hardness kernel and local hardness is performed to propose new definitions for these quantities that follow a similar pattern to the one that characterizes the quantities associated with softness, that is, we have derived new definitions for which the integral of the hardness kernel over the whole space of one of the variables leads to local hardness, and the integral of local hardness over the whole space leads to global hardness. A basic aspect of the present approach is that global hardness keeps its identity as the second derivative of energy with respect to the number of electrons. Local hardness thus obtained depends on the first and second derivatives of energy and electron density with respect to the number of electrons. When these derivatives are approximated by a smooth quadratic interpolation of energy, the expression for local hardness reduces to the one intuitively proposed by Meneses, Tiznado, Contreras and Fuentealba. However, when one combines the first directional derivatives with smooth second derivatives one finds additional terms that allow one to differentiate local hardness for electrophilic attack from the one for nucleophilic attack. Numerical results related to electrophilic attacks on substituted pyridines, substituted benzenes and substituted ethenes are presented to show the overall performance of the new definition.

Dinâmica populacional da mariposa oriental em pomares de pessegueiro e ameixeira

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Hickel Eduardo Rodrigues

2003-01-01

Full Text Available O objetivo deste trabalho foi estudar a dinâmica populacional da mariposa oriental [Grapholita molesta (Busk] em pomares de pessegueiro e ameixeira. Os adultos foram monitorados em dois pomares de pessegueiro e um de ameixeira por cinco anos. Séries temporais equivalentes de temperaturas máximas e mínimas foram correlacionadas aos dados de flutuação populacional para se aferir a correspondência entre a ocorrência da praga e as flutuações de temperatura. A análise de Fourier das séries temporais das armadilhas de coleta de mariposas revelou dinâmicas cíclicas, com período principal médio de 53,91 semanas. Um período menor médio, de 7,45 semanas, também ficou evidente e se aproxima do tempo médio de geração do inseto. A análise do espectro de potência das séries temporais, com e sem periodicidade, revelou que a dinâmica populacional de G. molesta possui um componente regular, caracterizado pelos períodos observados, e outro componente irregular, reminiscente de ruído 1/f, caracterizado pelas variações de amplitude, aparentemente irregulares, na ocorrência do inseto. A combinação desses dois componentes ocasiona um processo com domínio de baixas freqüências, próprio das dinâmicas periódicas ruidosas. Os ciclos de aparecimento da praga ocorrem em fase com os ciclos de flutuação de temperaturas máximas e mínimas.

Copies, Concepts and Time

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Anne Eriksen

2017-09-01

Full Text Available Copies are defined by their relation to an original. The understanding and evaluation of this relationship has been changing over time. A main argument of this article is that originals and copies are phenomena with no "natural" or essential meaning outside of their specific historical settings. The idea to be explored is how changing historicity regimes have transformed notions of originals and copies over time and how these differences also are reflected in the intrinsically temporal relation between the two concepts. The discussion will be framed by two theory sets. The first is Alexander Nagel and Christopher Woods investigation of two kinds of temporality that vied for dominance in works of art in the late Middle Ages and the Renaissance. The second is Walter Benjamins discussion of artwork in the "age of mechanical reproduction", i.e. the twentieth century. The second half of the article seeks to add to the historical complexity described by both theory sets by introducing a concept of tradition and discussing the early modern ideals of exemplarity, emulation and copiousness.

Manufacturing of microcomponents in a research institute under DIN EN ISO 9001

Science.gov (United States)

Maas, Dieter; Karl, Bernhard; Saile, Volker; Schulz, Joachim

2000-08-01

The Institute for Microstructure Technology at Forschungszentrum Karlsruhe has implemented a rigorous quality management system and was certified according to the DIN ISO EN 9001 standard in January 2000.

Adam Smith y Sistemas Dinámicos

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Osvaldo Acuña

2008-01-01

Full Text Available Presentamos un sistema dinámico sencillo con dos ecuaciones diferenciales, una representa la trayectoria del precio y la otra la de la cantidad de un bien en una economía. Nuestro modelo se basa sobre todo en la teoría clásica de precios expuesta por Adam Smith en La Riqueza de las Naciones. Al final del trabajo, se presenta, a modo de ejemplo, un estudio para el caso del ganado vacuno en la economía mundial.

Insuficiencia dinámica, crecimiento y desempleo en México, 1974-2012

OpenAIRE

Vargas, Blanca L. Avendaño; Hernández, Ignacio Perrotini

2015-01-01

El artículo presenta una reformulación de la hipótesis de insuficiencia dinámica de Prebisch (1970), analiza la teoría dinámica de Harrod (1939), la ley Kaldor-Verdoorn (Kaldor, 1966; 1967) y la teoría del crecimiento endógeno de Thirlwall (1969; 2000)Thirlwall and León-Ledesma, 2000. A posteriori estudiamos los determinantes del crecimiento económico y del desempleo en México durante el periodo 1974-2012. Con base en el análisis empírico, sostenemos que una baja tasa de acumulación genera una...

Ultrasonic testing and inspection of steel castings for use in elevated temperatures acc. to DIN 17245

International Nuclear Information System (INIS)

Christianus, D.; Fischer, K.H.

1978-01-01

Up to present, the non-destructive testing in german steel castings and delivery conditions has hardly been described. DIN 17245 was an exception for heat-resistant ferrite cast steel (July 1967 version) which for the first time contained data on maximum permissible defects in irradiation testing. The US (ultrasonic) method to find internal defects was named together with irradiation, the error limits however were also valid for this method according to the reference picture series of ASTM (American Society for Testing and Materials). It is clear to every practician that especially in the case of steel, due to the numerous possible defects and their unpredictable orientation, it is not always possible to determine the true type of defects based on reflection behaviour of an inhomogenity. In any case one cannot directly compare two physically different methods. If one considers foreign cast steel norms, then one finds somewhat more about non-destructive testing. The set standard measures mostly however take after the irradiation testing guidelines according to ASTM. A Westinghouse regulation, norm ASTM-A-609 and the ASME (Am. Soc. of Mech. Engineers) regulations for components of nuclear reactors are the exception. (orig.) [de

The DinJ/RelE Toxin-Antitoxin System Suppresses Bacterial Proliferation and Virulence of Xylella fastidiosa in Grapevine.

Science.gov (United States)

Burbank, Lindsey P; Stenger, Drake C

2017-04-01

Xylella fastidiosa, the causal agent of Pierce's disease of grapes, is a slow-growing, xylem-limited, bacterial pathogen. Disease progression is characterized by systemic spread of the bacterium through xylem vessel networks, causing leaf-scorching symptoms, senescence, and vine decline. It appears to be advantageous to this pathogen to avoid excessive blockage of xylem vessels, because living bacterial cells are generally found in plant tissue with low bacterial cell density and minimal scorching symptoms. The DinJ/RelE toxin-antitoxin system is characterized here for a role in controlling bacterial proliferation and population size during plant colonization. The DinJ/RelE locus is transcribed from two separate promoters, allowing for coexpression of antitoxin DinJ with endoribonuclease toxin RelE, in addition to independent expression of RelE. The ratio of antitoxin/toxin expressed is dependent on bacterial growth conditions, with lower amounts of antitoxin present under conditions designed to mimic grapevine xylem sap. A knockout mutant of DinJ/RelE exhibits a hypervirulent phenotype, with higher bacterial populations and increased symptom development and plant decline. It is likely that DinJ/RelE acts to prevent excessive population growth, contributing to the ability of the pathogen to spread systemically without completely blocking the xylem vessels and increasing probability of acquisition by the insect vector.

The Hegemony of the Copy

DEFF Research Database (Denmark)

Graulund, Rune

2017-01-01

This essay questions when the creative process leading tothe original can be said to be complete. When does the series of a pupil’sbotched attempts at perfection leading to “the” singular and unique object,text, tool, or artwork we recognise as the original expression of themaster craftsman stop......? Where is the cut-off point between the differentversions (copies) of earlier inferior iterations in the gestation process thatlead to the original, and final, superior original? This essay chiefly examinesthe manner in which text has been copied and stored in one particulartype of object, namely...... that of the book, in order to provide some fairlywell-known arguments regarding pre-mechanical as well as mechanical reproduction.In particular, it examines the differences between manuscriptculture and print culture as we see them expressed in the production (andreproduction) of master copies and subsequent...

40 CFR 264.53 - Copies of contingency plan.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Copies of contingency plan. 264.53... Contingency Plan and Emergency Procedures § 264.53 Copies of contingency plan. A copy of the contingency plan... called upon to provide emergency services. [Comment: The contingency plan must be submitted to the...

Modelagem de uma unidade de produção para caprinos leiteiros utilizando a dinâmica de sistemas

OpenAIRE

Guimarães, Vinicius Pereira

2007-01-01

O trabalho foi desenvolvido buscando abordar as características de dinâmica, complexidade e inter- relacionamento de um sistema de produção de caprinos. Buscou-se, através da metodologia de modelagem e simulação Dinâmica de Sistemas, identificar o impacto na dinâmica e rentabilidade econômica de rebanhos caprinos leiteiros provocados por modificações no manejo reprodutivo, mortalidade, qualidade do alimento e na idade para o início da vida reprodutiva em cabritas. Buscou-se também avaliar a u...

Evolución Dinámica de Cúmulos Estelares Abiertos

Science.gov (United States)

de La Fuente Marcos, R.

Las estrellas que observamos no se formaron aisladamente, sino que lo hicieron en grupos o cúmulos. Estos sistemas estelares recibenel nombre de cúmulos estelares abiertos o galácticos cuando están constituidos por estrellas de la Población I. Los cúmulos abiertos se localizan preferentemente en el plano galáctico, y en muchos de ellos está teniendo lugar aún una activa formación estelar. El propósito principal de esta tesis doctoral es el estudio de la evolución dinámica de estos sistemas estelares por medio de simulaciones numéricas y de la comparación de sus resultados con datos observacionales. Con este fin se analizan los efectos que, sobre la dinámica de los cúmulos, ejercen varios fenómenos de interés astrofísico tales como el campo gravitatorio galáctico, la pérdida de masa causada por la evolución estelar y la presencia de binarias primordiales. En este trabajo se presentan los resultados de más de un centenar de modelos de cúmulos, con poblaciones comprendidas en el intervalo [100, 10.000] estrellas, calculados con NBODY5, un programa estándar en el campo de la Dinámica Estelar Experimental. De los mismos se deduce que el mecanismo principal que rige la dinámica de los cúmulos abiertos es la evolución estelar de su distribución de masas, encontrándose un comportamiento diferencial fuertemente dependiente de la población inicial del cúmulo. Los mecanismos responsables de la desintegración de los cúmulos abiertos son analizados en detalle, proponiéndose un modelo analítico que ajusta razonablemente los resultados de las simulaciones. Además, y con el fin de explicar el elevado número de sistemas múltiples observados en cúmulos abiertos, se estudian los efectos que, sobre los mismos, ejerce la presencia de una cierta fracción de binarias primordiales. El papel de las binarias tambiín depende de la riqueza del cúmulo y sus efectos se interrelacionan con aquellos debidos a la evolución estelar. Por último, se

40 CFR 265.53 - Copies of contingency plan.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Copies of contingency plan. 265.53... DISPOSAL FACILITIES Contingency Plan and Emergency Procedures § 265.53 Copies of contingency plan. A copy of the contingency plan and all revisions to the plan must be: (a) Maintained at the facility; and (b...

DNA Polymerases ImuC and DinB Are Involved in DNA Alkylation Damage Tolerance in Pseudomonas aeruginosa and Pseudomonas putida.

Science.gov (United States)

Jatsenko, Tatjana; Sidorenko, Julia; Saumaa, Signe; Kivisaar, Maia

2017-01-01

Translesion DNA synthesis (TLS), facilitated by low-fidelity polymerases, is an important DNA damage tolerance mechanism. Here, we investigated the role and biological function of TLS polymerase ImuC (former DnaE2), generally present in bacteria lacking DNA polymerase V, and TLS polymerase DinB in response to DNA alkylation damage in Pseudomonas aeruginosa and P. putida. We found that TLS DNA polymerases ImuC and DinB ensured a protective role against N- and O-methylation induced by N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) in both P. aeruginosa and P. putida. DinB also appeared to be important for the survival of P. aeruginosa and rapidly growing P. putida cells in the presence of methyl methanesulfonate (MMS). The role of ImuC in protection against MMS-induced damage was uncovered under DinB-deficient conditions. Apart from this, both ImuC and DinB were critical for the survival of bacteria with impaired base excision repair (BER) functions upon alkylation damage, lacking DNA glycosylases AlkA and/or Tag. Here, the increased sensitivity of imuCdinB double deficient strains in comparison to single mutants suggested that the specificity of alkylated DNA lesion bypass of DinB and ImuC might also be different. Moreover, our results demonstrated that mutagenesis induced by MMS in pseudomonads was largely ImuC-dependent. Unexpectedly, we discovered that the growth temperature of bacteria affected the efficiency of DinB and ImuC in ensuring cell survival upon alkylation damage. Taken together, the results of our study disclosed the involvement of ImuC in DNA alkylation damage tolerance, especially at low temperatures, and its possible contribution to the adaptation of pseudomonads upon DNA alkylation damage via increased mutagenesis.

A dinâmica da gestão no contexto acadêmico

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Nadi Helena Presser

2011-09-01

Full Text Available Apresenta um estudo da dinâmica da gestão, procurando avançar no assunto, a partir das constatações de Mintzberg (2001, 2010, desmistificando o gestor nas suas características convencionais prescritas pela teoria clássica de administração, denotado como um planejador sistemático, que trabalha de forma programada, sem interrupções, e possuidor de um controle amplo de seu trabalho na organização. O objeto empírico desta pesquisa estendeu sua ação no ambiente organizacional de um departamento universitário federal, no contexto da gestão acadêmica dos cursos de graduação e do programa de pós-graduação. Com apoio numa metodologia de pesquisa etnográfica e de entrevistas semiestruturadas, observou-se um ambiente de gestão caracterizado pela ambiguidade, por uma dinâmica acelerada de tarefas diversificadas. Conclui-se que as análises sobre a prática da gestão teriam a ganhar se procurassem perscrutar esta realidade. A premissa sobre a dinâmica da gestão defendida por Mintzberg encontra sustentação neste estudo, cuja essência é descrita muito mais como uma prática do que como uma ciência.

Gauge and non-gauge curvature tensor copies

International Nuclear Information System (INIS)

Srivastava, P.P.

1982-10-01

A procedure for constructing curvature tensor copies is discussed using the anholonomic geometrical framework. The corresponding geometries are compared and the notion of gauge copy is elucidated. An explicit calculation is also made. (author)

Primeros pasos en la posturografía dinámica computarizada

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Cristina CORDERO-CIVANTOS

2018-01-01

Full Text Available Introducción y objetivo: La posturografía dinámica computarizada (CDP es una técnica que nos va a permitir cuantificar de forma objetiva, como las diferentes patologías afectan la estabilidad postural de los pacientes y su evolución. Metodología: revisión narrativa. Resultados: En este trabajo vamos a repasar como se realizan y analizan las diferentes pruebas de la CDP; y su utilidad diagnóstica y terapéutica en la práctica otorrinolaringológica. Discusión y conclusiones: La posturografía dinámica computarizada es una prueba diagnóstico-terapéutica que permite cuantificar de forma objetiva y reproducible la estabilidad del paciente. Y aporta información relevante para planificar el tratamiento rehabilitador, así como para monitorizar su evolución.

Gauge field copies and Higgs mechanism

International Nuclear Information System (INIS)

Gleiser, M.

1982-07-01

From the algebric classification of the possible solutions of the necessary and sufficient condition for the existence of gauge field copies in two possible classes the Higgs mechanism for the potential obtained from the difference between two copied potentials is applied. It is shown that for class I 'electric type' it is possible to construct a vector field that satisfies an electromagnetic wave equation. For class I 'magnetic type', a vector field that satisfies a non-linear equation as a consequence of the non-abelianity of the theory, is obtained. It is shown that for class II it's not possible to apply the Higgs mechanism. A possible physical interpretation for the 'gauge field copies' phenomenon, is obtained. (author) [pt

CONŢINUTUL METALELOR GRELE ÎN COMPONENTELE MEDIULUI DIN ZONA DE CENTRU A REPUBLICII MOLDOVA

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Olesea GLIGA

2016-02-01

Full Text Available Scopul acestei lucrări rezidă în determinarea conţinutului unor metale grele (Pb, Cd şi Cu în componentele mediu­lui (sol, apă şi floră din zona de centru a Republicii Moldova. Au fost selectate 4 situri de studiu, cu diferit impact antropic, din care au fost prelevate probe de sol, apă şi floră. Conţinutul de metale grele în componentele de mediu au fost deter­minate prin Spectrometria de Absorbţie Atomică cu atomizare termică. Rezultatele cercetărilor au demonstrat prezenţa metalelor cercetate în toate probele de sol şi floră analizate şi lipsa acestora în probele de apă, cu excepţia Cu. Concen­tra­ţiile de Pb, Cd şi Cu în solurile din siturile antropizate (industrial şi transport auto au fost mai mari în comparaţie cu cele din situl forestier (td = 2,05 - 4,36; P < 0,05 - 0,001. Analogic celor din sol, şi concentraţiile acestora în flora meliferă pre­levată din siturile antropizate au înregistrat valori mai mari în comparaţie cu cel forestier (td = 1,19 - 4,0; P > 0,1 - <0,001. De asemenea, şi concentraţia de Cu în mostrele de apă prelevate din siturile industrial şi transport auto a fost mai mare în comparaţie cu cele din situl forestier (td = 2,0 - 5,17; P < 0,1- 0,001. Putem constata că concentraţia metalelor grele cercetate în componentele mediului este în funcţie de prezenţa surselor de poluare din aceste situri. Totodată, în toate siturile cercetate nu au fost constatate depăşiri ale nivelurilor maximal admisibile, conform normelor în vigoare. THE CONTENT OF HEAVY METALS IN THE ENVIRONMENTAL COMPONENTS IN THE CENTRAL AREA OF THE REPUBLIC OF MOLDOVA The aim of this paper was to determine the content of heavy metals (Pb, Cd and Cu in the environmental components (soil, water and flora in the central area of the Republicof Moldova. Have been selected 4 study sites with different human impact, from which have been collected samples of soil, water and flora. The heavy metal

COMPONENŢA AMINOACIZILOR DIN BIOMASA ALGEI CIANOFITE NOSTOC GELATINOSUM (SCHOUSB ELENK.

Directory of Open Access Journals (Sweden)

Sergiu DOBROJAN

2016-02-01

Full Text Available În articol este analizată componenţa aminoacizilor din biomasa algei cianofite Nostoc gelatinosum (Schousb Elenk. colectate de pe mediul nutritiv Drew. Din grupa aminoacizilor esenţiali în biomasa algei Nostoc gelatinosum (Schousb Elenk. se conţine în cantităţi majore leucina (2,142±0,06 mg/100 mg, treonina (1,188±0,02 mg/100 mg şi valina (1,085±0,03 mg/100 mg. Din aminoacizii neesenţiali predomină acidul aspartic (4,523±0,11 mg/100 mg şi acidul glutamic (2,774±0,07 mg/100 mg. Alga Nostoc gelatinosum (Schousb Elenk. are un conţinut bogat de aminoacizi şi poate servi ca sursă pentru vaste domenii de aplicare.THE AMINO ACIDS COMPOSITION OF THE BLUE-GREEN ALGANOSTOC GELATINOSUM (SCHOUSB ELENKThis article presents the amino acid content of the blue-green alga Nostoc gelatinosum (Schousb Elenk. collected from the Drew nutritive medium. From the essential amino group in Nostoc gelatinosum (Schousb Elenk. biomass, major amounts are contained leucine (2,142 ± 0,06 mg/100 mg, threonine (1,188 ± 0,02 mg/100 mg and valine (1,085 ± 0,03 mg/100 mg. From nonessential amino acids predominates aspartic acid (4,523 ± 0,11 mg/100 mg and glutamic acid (2,774 ± 0.07 mg/100 mg. The alga Nostoc gelatinosum (Schousb Elenk. has a high content of amino acids and can serve as a source for vast areas of application. 

Partitioning of copy-number genotypes in pedigrees

Directory of Open Access Journals (Sweden)

Andelfinger Gregor U

2010-05-01

Full Text Available Abstract Background Copy number variations (CNVs and polymorphisms (CNPs have only recently gained the genetic community's attention. Conservative estimates have shown that CNVs and CNPs might affect more than 10% of the genome and that they may be at least as important as single nucleotide polymorphisms in assessing human variability. Widely used tools for CNP analysis have been implemented in Birdsuite and PLINK for the purpose of conducting genetic association studies based on the unpartitioned total number of CNP copies provided by the intensities from Affymetrix's Genome-Wide Human SNP Array. Here, we are interested in partitioning copy number variations and polymorphisms in extended pedigrees for the purpose of linkage analysis on familial data. Results We have developed CNGen, a new software for the partitioning of copy number polymorphism using the integrated genotypes from Birdsuite with the Affymetrix platform. The algorithm applied to familial trios or extended pedigrees can produce partitioned copy number genotypes with distinct parental alleles. We have validated the algorithm using simulations on a complex pedigree structure using frequencies calculated from a real dataset of 300 genotyped samples from 42 pedigrees segregating a congenital heart defect phenotype. Conclusions CNGen is the first published software for the partitioning of copy number genotypes in pedigrees, making possible the use CNPs and CNVs for linkage analysis. It was implemented with the Python interpreter version 2.5.2. It was successfully tested on current Linux, Windows and Mac OS workstations.

Measurement methods and accuracy in copy number variation: failure to replicate associations of beta-defensin copy number with Crohn's disease

Science.gov (United States)

Aldhous, Marian C.; Abu Bakar, Suhaili; Prescott, Natalie J.; Palla, Raquel; Soo, Kimberley; Mansfield, John C.; Mathew, Christopher G.; Satsangi, Jack; Armour, John A.L.

2010-01-01

The copy number variation in beta-defensin genes on human chromosome 8 has been proposed to underlie susceptibility to inflammatory disorders, but presents considerable challenges for accurate typing on the scale required for adequately powered case–control studies. In this work, we have used accurate methods of copy number typing based on the paralogue ratio test (PRT) to assess beta-defensin copy number in more than 1500 UK DNA samples including more than 1000 cases of Crohn's disease. A subset of 625 samples was typed using both PRT-based methods and standard real-time PCR methods, from which direct comparisons highlight potentially serious shortcomings of a real-time PCR assay for typing this variant. Comparing our PRT-based results with two previous studies based only on real-time PCR, we find no evidence to support the reported association of Crohn's disease with either low or high beta-defensin copy number; furthermore, it is noteworthy that there are disagreements between different studies on the observed frequency distribution of copy number states among European controls. We suggest safeguards to be adopted in assessing and reporting the accuracy of copy number measurement, with particular emphasis on integer clustering of results, to avoid reporting of spurious associations in future case–control studies. PMID:20858604

Measurement methods and accuracy in copy number variation: failure to replicate associations of beta-defensin copy number with Crohn's disease.

Science.gov (United States)

Aldhous, Marian C; Abu Bakar, Suhaili; Prescott, Natalie J; Palla, Raquel; Soo, Kimberley; Mansfield, John C; Mathew, Christopher G; Satsangi, Jack; Armour, John A L

2010-12-15

The copy number variation in beta-defensin genes on human chromosome 8 has been proposed to underlie susceptibility to inflammatory disorders, but presents considerable challenges for accurate typing on the scale required for adequately powered case-control studies. In this work, we have used accurate methods of copy number typing based on the paralogue ratio test (PRT) to assess beta-defensin copy number in more than 1500 UK DNA samples including more than 1000 cases of Crohn's disease. A subset of 625 samples was typed using both PRT-based methods and standard real-time PCR methods, from which direct comparisons highlight potentially serious shortcomings of a real-time PCR assay for typing this variant. Comparing our PRT-based results with two previous studies based only on real-time PCR, we find no evidence to support the reported association of Crohn's disease with either low or high beta-defensin copy number; furthermore, it is noteworthy that there are disagreements between different studies on the observed frequency distribution of copy number states among European controls. We suggest safeguards to be adopted in assessing and reporting the accuracy of copy number measurement, with particular emphasis on integer clustering of results, to avoid reporting of spurious associations in future case-control studies.

The double copy: Bremsstrahlung and accelerating black holes

CERN Document Server

Luna, Andres; Nicholson, Isobel; O'Connell, Donal; White, Chris D

2016-01-01

Advances in our understanding of perturbation theory suggest the existence of a correspondence between classical general relativity and Yang-Mills theory. A concrete example of this correspondence, which is known as the double copy, was recently introduced for the case of stationary Kerr-Schild spacetimes. Building on this foundation, we examine the simple time-dependent case of an accelerating, radiating point source. The gravitational solution, which generalises the Schwarzschild solution, includes a non-trivial stress-energy tensor. This stress-energy tensor corresponds to a gauge theoretic current in the double copy. We interpret both of these sources as representing the radiative part of the field. Furthermore, in the simple example of Bremsstrahlung, we determine a scattering amplitude describing the radiation, maintaining the double copy throughout. Our results provide the strongest evidence yet that the classical double copy is directly related to the BCJ double copy for scattering amplitudes.

Mycobacterium tuberculosis DinG is a structure-specific helicase that unwinds G4 DNA: implications for targeting G4 DNA as a novel therapeutic approach.

Science.gov (United States)

Thakur, Roshan Singh; Desingu, Ambika; Basavaraju, Shivakumar; Subramanya, Shreelakshmi; Rao, Desirazu N; Nagaraju, Ganesh

2014-09-05

The significance of G-quadruplexes and the helicases that resolve G4 structures in prokaryotes is poorly understood. The Mycobacterium tuberculosis genome is GC-rich and contains >10,000 sequences that have the potential to form G4 structures. In Escherichia coli, RecQ helicase unwinds G4 structures. However, RecQ is absent in M. tuberculosis, and the helicase that participates in G4 resolution in M. tuberculosis is obscure. Here, we show that M. tuberculosis DinG (MtDinG) exhibits high affinity for ssDNA and ssDNA translocation with a 5' → 3' polarity. Interestingly, MtDinG unwinds overhangs, flap structures, and forked duplexes but fails to unwind linear duplex DNA. Our data with DNase I footprinting provide mechanistic insights and suggest that MtDinG is a 5' → 3' polarity helicase. Notably, in contrast to E. coli DinG, MtDinG catalyzes unwinding of replication fork and Holliday junction structures. Strikingly, we find that MtDinG resolves intermolecular G4 structures. These data suggest that MtDinG is a multifunctional structure-specific helicase that unwinds model structures of DNA replication, repair, and recombination as well as G4 structures. We finally demonstrate that promoter sequences of M. tuberculosis PE_PGRS2, mce1R, and moeB1 genes contain G4 structures, implying that G4 structures may regulate gene expression in M. tuberculosis. We discuss these data and implicate targeting G4 structures and DinG helicase in M. tuberculosis could be a novel therapeutic strategy for culminating the infection with this pathogen. © 2014 by The American Society for Biochemistry and Molecular Biology, Inc.

The λ transformation and gravitational copies

International Nuclear Information System (INIS)

Silva, M.R. da.

1984-01-01

An Abelian symmetry already considered by Einstein with respect to his asymmetrical field theories is related to the gravitational and gauge field copy phenomenon. It is shown that gauge field copies arise out of a straightforward generalization of the λ - map. The connection between Einstein's work on the λ-transformation and the copy phenomenon is obtained with the help of the Frobenius Theorem on the existence of foliations on a differentiable manifold. A problem like the one above is usually treated within the language of (intrinsic) Differential Geometry; General Relativity and classical unified field theories are traditionally developed in a classical style, that gap, a long introduction is prepared where the same structures are studied from the traditional and from the more recent point of view. (author)

EVALUAREA POTENŢIALULUI PATRIMONIAL AL ÎNTREPRINDERILOR ŞI ORGANIZAŢIILOR DIN SISTEMUL COOPERAŢIEI DE CONSUM DIN REPUBLICA MOLDOVA

Directory of Open Access Journals (Sweden)

Natalia CHIBERCEA

2018-03-01

Full Text Available În articol este efectuată o analiză a situaţiei financiar-patrimoniale a entităților economice din sistemul cooperației de consum din Republica Moldova, ceea ce a permis autorului să constate că aceasta indică o stare concretă a capitalului entității economice, reprezentând rezultatul realizării scopului activității întreprinderii. În mod particular, în urma desfăşurării reuşite a activităţii economico-financiare, se constată o creştere a activelor controlate de întreprindere, fapt ce reflectă extinderea activităţii de întreprinzător şi sporirea potenţialului economico-financiar.EVALUATION OF THE PATRIMONIAL POTENTIAL OF THE ENTERPRISES AND ORGANIZATIONS FROM THE CONSUMER COOPERATION SYSTEM OF THE REPUBLIC OF MOLDOVAThis article reflects the analysis of the financial-patrimonial situation of economic entities from the consumer coope­ration system of theRepublicofMoldova, which in general made possible to ascertain that this is a concrete state of the economic entity's capital, representing the result of achieving the purpose of the enterprise's activity. In particular, following the successful conduct of the economic and financial activity, there is an increase in the assets controlled by the enterprise, which reflects the widening of the entrepreneurial activity and increasing economic and financial potential.

DNA replication stress restricts ribosomal DNA copy number.

Science.gov (United States)

Salim, Devika; Bradford, William D; Freeland, Amy; Cady, Gillian; Wang, Jianmin; Pruitt, Steven C; Gerton, Jennifer L

2017-09-01

Ribosomal RNAs (rRNAs) in budding yeast are encoded by ~100-200 repeats of a 9.1kb sequence arranged in tandem on chromosome XII, the ribosomal DNA (rDNA) locus. Copy number of rDNA repeat units in eukaryotic cells is maintained far in excess of the requirement for ribosome biogenesis. Despite the importance of the repeats for both ribosomal and non-ribosomal functions, it is currently not known how "normal" copy number is determined or maintained. To identify essential genes involved in the maintenance of rDNA copy number, we developed a droplet digital PCR based assay to measure rDNA copy number in yeast and used it to screen a yeast conditional temperature-sensitive mutant collection of essential genes. Our screen revealed that low rDNA copy number is associated with compromised DNA replication. Further, subculturing yeast under two separate conditions of DNA replication stress selected for a contraction of the rDNA array independent of the replication fork blocking protein, Fob1. Interestingly, cells with a contracted array grew better than their counterparts with normal copy number under conditions of DNA replication stress. Our data indicate that DNA replication stresses select for a smaller rDNA array. We speculate that this liberates scarce replication factors for use by the rest of the genome, which in turn helps cells complete DNA replication and continue to propagate. Interestingly, tumors from mini chromosome maintenance 2 (MCM2)-deficient mice also show a loss of rDNA repeats. Our data suggest that a reduction in rDNA copy number may indicate a history of DNA replication stress, and that rDNA array size could serve as a diagnostic marker for replication stress. Taken together, these data begin to suggest the selective pressures that combine to yield a "normal" rDNA copy number.

DNA replication stress restricts ribosomal DNA copy number

Science.gov (United States)

Salim, Devika; Bradford, William D.; Freeland, Amy; Cady, Gillian; Wang, Jianmin

2017-01-01

Ribosomal RNAs (rRNAs) in budding yeast are encoded by ~100–200 repeats of a 9.1kb sequence arranged in tandem on chromosome XII, the ribosomal DNA (rDNA) locus. Copy number of rDNA repeat units in eukaryotic cells is maintained far in excess of the requirement for ribosome biogenesis. Despite the importance of the repeats for both ribosomal and non-ribosomal functions, it is currently not known how “normal” copy number is determined or maintained. To identify essential genes involved in the maintenance of rDNA copy number, we developed a droplet digital PCR based assay to measure rDNA copy number in yeast and used it to screen a yeast conditional temperature-sensitive mutant collection of essential genes. Our screen revealed that low rDNA copy number is associated with compromised DNA replication. Further, subculturing yeast under two separate conditions of DNA replication stress selected for a contraction of the rDNA array independent of the replication fork blocking protein, Fob1. Interestingly, cells with a contracted array grew better than their counterparts with normal copy number under conditions of DNA replication stress. Our data indicate that DNA replication stresses select for a smaller rDNA array. We speculate that this liberates scarce replication factors for use by the rest of the genome, which in turn helps cells complete DNA replication and continue to propagate. Interestingly, tumors from mini chromosome maintenance 2 (MCM2)-deficient mice also show a loss of rDNA repeats. Our data suggest that a reduction in rDNA copy number may indicate a history of DNA replication stress, and that rDNA array size could serve as a diagnostic marker for replication stress. Taken together, these data begin to suggest the selective pressures that combine to yield a “normal” rDNA copy number. PMID:28915237

DNA replication stress restricts ribosomal DNA copy number.

Directory of Open Access Journals (Sweden)

Devika Salim

2017-09-01

Full Text Available Ribosomal RNAs (rRNAs in budding yeast are encoded by ~100-200 repeats of a 9.1kb sequence arranged in tandem on chromosome XII, the ribosomal DNA (rDNA locus. Copy number of rDNA repeat units in eukaryotic cells is maintained far in excess of the requirement for ribosome biogenesis. Despite the importance of the repeats for both ribosomal and non-ribosomal functions, it is currently not known how "normal" copy number is determined or maintained. To identify essential genes involved in the maintenance of rDNA copy number, we developed a droplet digital PCR based assay to measure rDNA copy number in yeast and used it to screen a yeast conditional temperature-sensitive mutant collection of essential genes. Our screen revealed that low rDNA copy number is associated with compromised DNA replication. Further, subculturing yeast under two separate conditions of DNA replication stress selected for a contraction of the rDNA array independent of the replication fork blocking protein, Fob1. Interestingly, cells with a contracted array grew better than their counterparts with normal copy number under conditions of DNA replication stress. Our data indicate that DNA replication stresses select for a smaller rDNA array. We speculate that this liberates scarce replication factors for use by the rest of the genome, which in turn helps cells complete DNA replication and continue to propagate. Interestingly, tumors from mini chromosome maintenance 2 (MCM2-deficient mice also show a loss of rDNA repeats. Our data suggest that a reduction in rDNA copy number may indicate a history of DNA replication stress, and that rDNA array size could serve as a diagnostic marker for replication stress. Taken together, these data begin to suggest the selective pressures that combine to yield a "normal" rDNA copy number.

Hacking DNA copy number for circuit engineering.

Science.gov (United States)

Wu, Feilun; You, Lingchong

2017-07-27

DNA copy number represents an essential parameter in the dynamics of synthetic gene circuits but typically is not explicitly considered. A new study demonstrates how dynamic control of DNA copy number can serve as an effective strategy to program robust oscillations in gene expression circuits.

The DNA damage-inducible dinD gene of Escherichia coli is equivalent to orfY upstream of pyrE

DEFF Research Database (Denmark)

Lundegaard, Claus; Jensen, Kaj Frank

1994-01-01

The DNA damage-inducible gene dinD, originally identified by Kenyon and Walker (C. J. Kenyon and G. C. Walker, Proc. Natl. Acad. Sci. USA 77:2819-2823, 1980) by selection of the dinD::MudI (Ap lac) fusion, is shown here to be equivalent to the open reading frame orfY near pyrE. The evidence...

Herramientas del álgebra lineal para el control de sistemas lineales dinámicos conmutados

OpenAIRE

Rivera Martínez, Laura

2016-01-01

En el presente proyecto se aborda una introducción a la teoría sobre Sistemas Lineales Dinámicos Conmutados (SLDC), con el propósito de estudiar su comportamiento, que posteriormente (en el Capítulo 5) será aplicada a un problema del ámbito de la ingeniería eléctrica : un circuito RLC. A tal fin, se recurre a la teoría generalizada sobre Sistemas Lineales Dinámicos (SLD), (fundamentada a partir de las referencias [1] y [6], esencialmente) en la cual se desarrolla una explicación detallada ...

Equações discretas no ensino médio: modelos de dinâmicas populacionais

OpenAIRE

Maligeri, Glaucía Cristina Alecci Meneghim [UNESP

2013-01-01

As equações discretas fornecem as ferramentas matemáticas básicas para a correta modelagem da dinâmica populacional ao se tomar como hipótese tempos discretos. Neste trabalho, apresentamos a teoria das equações discretas e algumas aplicações no capítulo 01, dando ênfase aos modelos de dinâmica populacional conhecidos como modelo de Malthus e de Verhulst junto com exemplos que evidenciam tais modelos na modelagem de populações reais. No capítulo 02 apresentamos duas propostas didáticas; a prim...

Dinâmica não-linear e psiquiatria: a natureza dinâmica das doenças mentais

Directory of Open Access Journals (Sweden)

Fernando Portela Câmara

2008-03-01

Full Text Available A psiquiatria moderna adotou a postura reducionista de associar psicopatologia à fisiologia sináptica. Isto produziu avanços importantes na farmacoterapia dos transtornos mentais. Entretanto, a introdução de princípios da dinâmica não-linear promoveu uma mudança do enfoque sináptico para o enfoque das vias específicas patologicamente autônomas envolvidas nos fenômenos psicopatológicos. Esta tendência teve início nos anos 1990 e trouxe um conceito mais sistêmico de fisiopatologia e tratamento em psiquiatria.

Elimination of Parallel Copies using Code Motion on Data Dependence Graphs

DEFF Research Database (Denmark)

Brandner, Florian; Colombet, Quentin

2013-01-01

, while at the same time a valid register assignment is preserved. Our results show that even after traditional register allocation with coalescing our technique is able to eliminate an additional 3% (up to 9%) of the remaining copies and reduce the weighted costs of register copies by up to 25......Register allocation regained much interest in recent years due to the development of decoupled strategies that split the problem into separate phases: spilling, register assignment, and copy elimination. Traditional approaches to copy elimination during register allocation are based on interference......% for the SPECINT 2000 benchmarks. In comparison to Parallel Copy Motion, our technique removes 11% (up to 20%) more copies and up to 39% more of the copy costs....

Assessment of the usefulness of telemammography for the second reading in screening mammography

International Nuclear Information System (INIS)

Okuda, Itsuko; Nakajima, Yasuo; Okazaki, Hiroko; Shimamoto, Hiroshi; Okamoto, Kyoko; Kanemaki, Yoshihide; Irimoto, Masahiro

2010-01-01

We assessed the usefulness of telemammography by soft-copy diagnosis. A wide area network for teleradiology was set up incorporating seven institutions located in two prefectures. A total of 1053 subjects were enrolled. The first reading was performed using hard-copy images at the institution where mammography was undertaken. The second reading using hard-copy images was then performed. These images were transferred to our institution, where a second reading based on soft-copy images was performed. The result of soft-copy diagnosis were then compared with those of the hard-copy diagnosis. The diagnosis concordance rate, which was higher than category 3, was evaluated. Category 1 or 2 accounted for 956 cases at the stage of the second hard-copy diagnosis, of which category 1 or 2 accounted for 930 cases analyzed in the second soft-copy diagnosis. A category higher than 3 accounted for 97 cases at the second hard-copy diagnosis, of which a category higher than 3 accounted for 75 cases at the stage of the second soft-copy diagnosis. The κ-value for the diagnosis concordance rate was 0.751. The diagnostic concordance between hard-copy diagnosis and soft-copy diagnosis was good. Diagnostic accuracy showed no significant difference between the two. We conclude that soft-copy diagnosis by telemammography is useful, and that its application is desirable for screening mammography. (author)

A comprehensive profile of DNA copy number variations in a Korean population: identification of copy number invariant regions among Koreans.

Science.gov (United States)

Jeon, Jae Pil; Shim, Sung Mi; Jung, Jong Sun; Nam, Hye Young; Lee, Hye Jin; Oh, Berm Seok; Kim, Kuchan; Kim, Hyung Lae; Han, Bok Ghee

2009-09-30

To examine copy number variations among the Korean population, we compared individual genomes with the Korean reference genome assembly using the publicly available Korean HapMap SNP 50 k chip data from 90 individuals. Korean individuals exhibited 123 copy number variation regions (CNVRs) covering 27.2 mb, equivalent to 1.0% of the genome in the copy number variation (CNV) analysis using the combined criteria of P value (Por= 0.25) among study subjects. In contrast, when compared to the Affymetrix reference genome assembly from multiple ethnic groups, considerably more CNVRs (n=643) were detected in larger proportions (5.0%) of the genome covering 135.1 mb even by more stringent criteria (Por=0.25), reflecting ethnic diversity of structural variations between Korean and other populations. Some CNVRs were validated by the quantitative multiplex PCR of short fluorescent fragment (QMPSF) method, and then copy number invariant regions were detected among the study subjects. These copy number invariant regions would be used as good internal controls for further CNV studies. Lastly, we demonstrated that the CNV information could stratify even a single ethnic population with a proper reference genome assembly from multiple heterogeneous populations.

A dinâmica do crédito no Brasil entre 1990-2006.

Directory of Open Access Journals (Sweden)

Juliano Morais Galle

2008-05-01

Full Text Available Este artigo aborda, dentro de um contexto de globalização financeira, a dinâmica e o desenvolvimento recente do mercado financeiro e de crédito no Brasil. É mostrado que a dinâmica do crédito se caracterizou por três fases distintas entre 1990 e 2003. Além disso, discute-se que, após a implantação do Plano Real, houve um grande esforço por parte do governo brasileiro em reestruturar e reforçar o Sistema Financeiro Nacional, e que a conjuntura econômica observada atualmente no Brasil é bem mais favorável ao crescimento da relação crédito/PIB que no início da década de 2000.

Metafísica y dinámica caótica

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Vicente Aboites

2009-01-01

Full Text Available From an internalist viewpoint for mental states, it is proposed that any dynamical system with coexisting chaotic attractors has an emergent property. This provides a non reductive explanation of mental states and their high sensitivity to noise and initial conditions. If metaphysical terms result from the mental states and these are emergent properties of dynamical systems with coexisting attractors, such as the brain, it is suggested that this may provide a physical explanation of metaphysical concepts. A partir de un enfoque internalista para los estados mentales, se propone que los términos metafísicos son el resultado de estados mentales que, a su vez, son propiedades emergentes de sistemas dinámicos caóticos con atractores coexistentes en el cerebro. Se sugiere que esto proporciona una explicación física para los conceptos metafísicos. Esto se hace a partir de la propuesta de que todos los sistemas dinámicos con atractores coexistentes caóticos, como el cerebro, presentan propiedades emergentes. Obtenemos así una explicación no reductiva de los estados mentales y su alta sensibilidad al ruido y a las condiciones iniciales.

A Comparison of Effective Tension Calculation for Design Belt Conveyor between CEMA and DIN Standard

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Satria Iman

2018-01-01

Full Text Available In the present era, many industries are demanding material transfer equipment that works maximally and cheaply. Belt Conveyor is one of the most efficient material transfer equipment compared to heavy equipment or other transportation equipment, because it can transport the material in large capacity. When designing conveyor belts, many industries want large transport capacity at low cost. One of the cost savings can be done with low motor power consumption. Many standards describe the effective tension calculation on the conveyor belt in detail with the parameters, since the effective tension calculation results are essential for determining motor power. This paper aims to analyze the effective tension on conveyor belts using CEMA 5th, CEMA 6th and DIN 22101 standards with case studies of 1000 TPH carrying capacity and 3 m/s conveyor speed. The difference between CEMA and DIN when determining the effective tension is on the use of coefficient of friction, because DIN uses a global coefficient of friction while CEMA uses different friction coefficients on idler, belt and material. This difference in coefficient of friction results in different ways of calculating the resistance being the accumulation of the effective tension. The result is an effective tension value using DIN 22101 standard of 22,148.16 N with motor power consumption of 66.5 kW, while effective tension value using CEMA 5th standard is 32.201.66 N with motor power consumption 96.47 kW, and effective tension value using CEMA 6th standard is 29,686.48 N with 89.06 kW motor power consumption.

Copy-number and gene dependency analysis reveals partial copy loss of wild-type SF3B1 as a novel cancer vulnerability. | Office of Cancer Genomics

Science.gov (United States)

Genomic instability is a hallmark of human cancer, and results in widespread somatic copy number alterations. We used a genome-scale shRNA viability screen in human cancer cell lines to systematically identify genes that are essential in the context of particular copy-number alterations (copy-number associated gene dependencies). The most enriched class of copy-number associated gene dependencies was CYCLOPS (Copy-number alterations Yielding Cancer Liabilities Owing to Partial losS) genes, and spliceosome components were the most prevalent.

Vocal copying of individually distinctive signature whistles in bottlenose dolphins

Science.gov (United States)

King, Stephanie L.; Sayigh, Laela S.; Wells, Randall S.; Fellner, Wendi; Janik, Vincent M.

2013-01-01

Vocal learning is relatively common in birds but less so in mammals. Sexual selection and individual or group recognition have been identified as major forces in its evolution. While important in the development of vocal displays, vocal learning also allows signal copying in social interactions. Such copying can function in addressing or labelling selected conspecifics. Most examples of addressing in non-humans come from bird song, where matching occurs in an aggressive context. However, in other animals, addressing with learned signals is very much an affiliative signal. We studied the function of vocal copying in a mammal that shows vocal learning as well as complex cognitive and social behaviour, the bottlenose dolphin (Tursiops truncatus). Copying occurred almost exclusively between close associates such as mother–calf pairs and male alliances during separation and was not followed by aggression. All copies were clearly recognizable as such because copiers consistently modified some acoustic parameters of a signal when copying it. We found no evidence for the use of copying in aggression or deception. This use of vocal copying is similar to its use in human language, where the maintenance of social bonds appears to be more important than the immediate defence of resources. PMID:23427174

Unsupervised DInSAR processing chain for multi-scale displacement analysis

Science.gov (United States)

Casu, Francesco; Manunta, Michele

2016-04-01

Earth Observation techniques can be very helpful for the estimation of several sources of ground deformation due to their characteristics of large spatial coverage, high resolution and cost effectiveness. In this scenario, Differential Synthetic Aperture Radar Interferometry (DInSAR) is one of the most effective methodologies for its capability to generate spatially dense deformation maps at both global and local spatial scale, with centimeter to millimeter accuracy. DInSAR exploits the phase difference (interferogram) between SAR image pairs relevant to acquisitions gathered at different times, but with the same illumination geometry and from sufficiently close flight tracks, whose separation is typically referred to as baseline. Among several, the SBAS algorithm is one of the most used DInSAR approaches and it is aimed at generating displacement time series at a multi-scale level by exploiting a set of small baseline interferograms. SBAS, and generally DInSAR, has taken benefit from the large availability of spaceborne SAR data collected along years by several satellite systems, with particular regard to the European ERS and ENVISAT sensors, which have acquired SAR images worldwide during approximately 20 years. Moreover, since 2014 the new generation of Copernicus Sentinel satellites has started to acquire data with a short revisit time (12 days) and a global coverage policy, thus flooding the scientific EO community with an unprecedent amount of data. To efficiently manage such amount of data, proper processing facilities (as those coming from the emerging Cloud Computing technologies) have to be used, as well as novel algorithms aimed at their efficient exploitation have to be developed. In this work we present a set of results achieved by exploiting a recently proposed implementation of the SBAS algorithm, namely Parallel-SBAS (P-SBAS), which allows us to effectively process, in an unsupervised way and in a limited time frame, a huge number of SAR images

"Dear Teacher, Johnny Copied."

Science.gov (United States)

Jackson, Louise A.; And Others

1987-01-01

Presents the problem of intentional or unintentional plagiarism on the part of young students, several possible causes for it, and offers ways teachers can help students avoid copying and understand the value of owning one's writing. (JC)

Sosyal Kurumlarda Din Hizmetleri Ve Sosyal Zekâ İlişkisi

Directory of Open Access Journals (Sweden)

Remziye Ege

2013-06-01

Full Text Available Bu makale sosyal zekâ çerçevesinde din hizmetleri uygulamalarının yeniden düşünülmesi konusunda bir farkındalık oluşturmayı hedeflemektedir. İlahiyat alanındaki mesleki uygulamalara odaklanarak bu uygulamalar içinde sosyal zekânın yeri tartışılmıştır. Bu bağlamda, makalede önce sosyal zekânın ne olduğu sorusu İyi Yürekli Samaryalı Meseli (Luka 10:25-37 ile ilgili bir araştırma özelinde ele alınmakta, daha sonra ise sosyal zekânın din hizmetleri uygulamaları alanındaki etkisi değerlendirilmektedir. Makalenin son bölümünde sosyal zekâyı geliştirme yolunda bazı öneriler sunulmuştur

38 CFR 1.526 - Copies of records and papers.

Science.gov (United States)

2010-07-01

... papers. 1.526 Section 1.526 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS... Copies of records and papers. (a) Any person desiring a copy of any record or document in the custody of... plain one-sided paper copies of a standard size (81/2″ × 11″; 81/2″ × 14″; 11″ × 14″) $0.15 per page...

The classical double copy for Taub–NUT spacetime

Energy Technology Data Exchange (ETDEWEB)

Luna, Andrés, E-mail: a.luna-godoy.1@research.gla.ac.uk [School of Physics and Astronomy, University of Glasgow, Glasgow G12 8QQ, Scotland (United Kingdom); Monteiro, Ricardo, E-mail: monteiro@maths.ox.ac.uk [Mathematical Institute, University of Oxford, Oxford OX2 6GG, England (United Kingdom); O' Connell, Donal, E-mail: donal@staffmail.ed.ac.uk [Higgs Centre for Theoretical Physics, School of Physics and Astronomy, The University of Edinburgh, Edinburgh EH9 3JZ, Scotland (United Kingdom); Kavli Institute for Theoretical Physics, University of California, Santa Barbara, CA 93106-4030 (United States); White, Chris D., E-mail: Christopher.White@glasgow.ac.uk [School of Physics and Astronomy, University of Glasgow, Glasgow G12 8QQ, Scotland (United Kingdom)

2015-11-12

The double copy is a much-studied relationship between gauge theory and gravity amplitudes. Recently, this was generalised to an infinite family of classical solutions to Einstein's equations, namely stationary Kerr–Schild geometries. In this paper, we extend this to the Taub–NUT solution in gravity, which has a double Kerr–Schild form. The single copy of this solution is a dyon, whose electric and magnetic charges are related to the mass and NUT charge in the gravity theory. Finally, we find hints that the classical double copy extends to curved background geometries.

La caja negra de la dinámica empresarial

Directory of Open Access Journals (Sweden)

María Callejón

2009-01-01

Full Text Available Este artículo intenta aportar conocimientos sobre la contribución a la política industrial de la investigación en dinámica empresarial. Los programas de fomento a la creación de empresas se han generalizado aunque se desconoce cuál es el ritmo óptimo de creación y destrucción empresarial. El análisis económico destaca la heterogeneidad empresarial como característica dominante en la dinámica industrial. La profundización en el conocimiento de los tipos de emprendedores, su comportamiento, y su contribución diferencial a la innovación y el crecimiento permitirá ver en la "caja negra" y diseñar programas públicos adecuados. El análisis empírico realizado encuentra que la naturaleza económica del autoempleo es muy diferente de las empresas con empleados. Los programas públicos deberían priorizar entrantes con capacidad de sobrevivir y no maximizar la entrada indiscriminadamente. La supervivencia de las nuevas empresas se encuentra positivamente relacionada con su tamaño al nacer. La innovación y la inversión mejoran la supervivencia de las nuevas empresas manufactureras. La inversión en I+D aumenta el riesgo de las nuevas empresas, aunque mejore la competitividad de las empresas establecidas.

La caja negra de la dinámica empresarial

Directory of Open Access Journals (Sweden)

María Callejón

2009-10-01

Full Text Available Este artículo intenta aportar conocimientos sobre la contribución a la política industrial de la investigación en dinámica empresarial. Los programas de fomento a la creación de empresas se han generalizado aunque se desconoce cuál es el ritmo óptimo de creación y destrucción empresarial. El análisis económico destaca la heterogeneidad empresarial como característica dominante en la dinámica industrial. La profundización en el conocimiento de los tipos de emprendedores, su comportamiento, y su contribución diferencial a la innovación y el crecimiento permitirá ver en la “caja negra” y diseñar programas públicos adecuados. El análisis empírico realizado encuentra que la naturaleza económica del autoempleo es muy diferente de las empresas con empleados. Los programas públicos deberían priorizar entrantes con capacidad de sobrevivir y no maximizar la entrada indiscriminadamente. La supervivencia de las nuevas empresas se encuentra positivamente relacionada con su tamaño al nacer. La innovación y la inversión mejoran la supervivencia de las nuevas empresas manufactureras. La inversión en I+D aumenta el riesgo de las nuevas empresas, aunque mejore la competitividad de las empresas establecidas.

Provocarea Facebook pentru bibliotecile publice din România

Directory of Open Access Journals (Sweden)

Octavia-Luciana Madge

2014-01-01

Full Text Available Reţelele sociale şi-au câştigat rapid un loc în viaţa noastră şi în activitatea multor organizaţii şi instituţii publice şi private. La nivelul bibliotecilor, reţelele sociale şi-au demonstrat utilitatea şi rolul în calitate de instrumente de marketing pentru o mai bună comunicare cu utilizatorii. Bibliotecile publice din România au cunoscut în ultimul timp transformări mari în ceea ce priveşte modul de abordare a relaţiei cu utilizatorii şi îmbunătăţirea activităţii lor. Au lansat, de asemenea, o serie de noi servicii pentru a răspunde nevoilor comunităţii pe care o servesc şi pentru a atrage noi utilizatori. Implementarea şi utilizarea de noi aplicaţii precum reţelele de socializare online, mai exact Facebook, a fost una dintre aceste dezvoltări recente. Această lucrare analizează modul în care reţelele sociale sunt utilizate la nivelul bibliotecilor publice din România prin exemplul a trei biblioteci publice mari şi a modului în care aceste biblioteci îşi promovează serviciile prin intermediul reţelei Facebook.

Dinâmicas de grupo orientadas pelas atividades de estudo: desenvolvimento de habilidades e competências na educação profissional

OpenAIRE

Alberti,Taís Fim; Abegg,Ilse; Costa,Márcia Rejane Julio; Titton,Mauro

2014-01-01

Explicita resultados de pesquisa sobre dinâmicas de grupo e sua contribuição para aquisição de conhecimentos teórico-práticos. Realizamos ações em uma escola pública federal, envolvendo estudantes do terceiro semestre do Curso Técnico em Administração de Empresas. Para coleta de dados, planejamos, implementamos e avaliamos sequência didática centrada em dinâmicas de grupos tematizadas pelos conteúdos curriculares. Utilizaram-se questionários abertos para avaliar se as dinâmicas de grupo poder...

29 CFR 1956.84 - Location of plan for inspection and copying.

Science.gov (United States)

2010-07-01

... 29 Labor 9 2010-07-01 2010-07-01 false Location of plan for inspection and copying. 1956.84... PLANS Illinois § 1956.84 Location of plan for inspection and copying. A copy of the plan may be inspected and copied during normal business hours at the following locations: Office of State Programs, U.S...

29 CFR 1956.64 - Location of plan for inspection and copying.

Science.gov (United States)

2010-07-01

... 29 Labor 9 2010-07-01 2010-07-01 false Location of plan for inspection and copying. 1956.64... PLANS New Jersey § 1956.64 Location of plan for inspection and copying. A copy of the plan may be inspected and copied during normal business hours at the following locations: Office of State Programs, U.S...

Quantum copying and simplification of the quantum Fourier transform

Science.gov (United States)

Niu, Chi-Sheng

Theoretical studies of quantum computation and quantum information theory are presented in this thesis. Three topics are considered: simplification of the quantum Fourier transform in Shor's algorithm, optimal eavesdropping in the BB84 quantum cryptographic protocol, and quantum copying of one qubit. The quantum Fourier transform preceding the final measurement in Shor's algorithm is simplified by replacing a network of quantum gates with one that has fewer and simpler gates controlled by classical signals. This simplification results from an analysis of the network using the consistent history approach to quantum mechanics. The optimal amount of information which an eavesdropper can gain, for a given level of noise in the communication channel, is worked out for the BB84 quantum cryptographic protocol. The optimal eavesdropping strategy is expressed in terms of various quantum networks. A consistent history analysis of these networks using two conjugate quantum bases shows how the information gain in one basis influences the noise level in the conjugate basis. The no-cloning property of quantum systems, which is the physics behind quantum cryptography, is studied by considering copying machines that generate two imperfect copies of one qubit. The best qualities these copies can have are worked out with the help of the Bloch sphere representation for one qubit, and a quantum network is worked out for an optimal copying machine. If the copying machine does not have additional ancillary qubits, the copying process can be viewed using a 2-dimensional subspace in a product space of two qubits. A special representation of such a two-dimensional subspace makes possible a complete characterization of this type of copying. This characterization in turn leads to simplified eavesdropping strategies in the BB84 and the B92 quantum cryptographic protocols.

Determination of beta-defensin genomic copy number in different populations

DEFF Research Database (Denmark)

Fode, Peder; Jespersgaard, Cathrine; Hardwick, Robert J

2011-01-01

There have been conflicting reports in the literature on association of gene copy number with disease, including CCL3L1 and HIV susceptibility, and ß-defensins and Crohn's disease. Quantification of precise gene copy numbers is important in order to define any association of gene copy number with...

Ernst Rüdin's Unpublished 1922-1925 Study "Inheritance of Manic-Depressive Insanity": Genetic Research Findings Subordinated to Eugenic Ideology.

Science.gov (United States)

Kösters, Gundula; Steinberg, Holger; Kirkby, Kenneth Clifford; Himmerich, Hubertus

2015-11-01

In the early 20th century, there were few therapeutic options for mental illness and asylum numbers were rising. This pessimistic outlook favoured the rise of the eugenics movement. Heredity was assumed to be the principal cause of mental illness. Politicians, scientists and clinicians in North America and Europe called for compulsory sterilisation of the mentally ill. Psychiatric genetic research aimed to prove a Mendelian mode of inheritance as a scientific justification for these measures. Ernst Rüdin's seminal 1916 epidemiological study on inheritance of dementia praecox featured large, systematically ascertained samples and statistical analyses. Rüdin's 1922-1925 study on the inheritance of "manic-depressive insanity" was completed in manuscript form, but never published. It failed to prove a pattern of Mendelian inheritance, counter to the tenets of eugenics of which Rüdin was a prominent proponent. It appears he withheld the study from publication, unable to reconcile this contradiction, thus subordinating his carefully derived scientific findings to his ideological preoccupations. Instead, Rüdin continued to promote prevention of assumed hereditary mental illnesses by prohibition of marriage or sterilisation and was influential in the introduction by the National Socialist regime of the 1933 "Law for the Prevention of Hereditarily Diseased Offspring" (Gesetz zur Verhütung erbkranken Nachwuchses).

Semifabricate din tocătură de carne de ovină cu adaos de şrot din seminţe de nuci, dovleac, in şi struguri

Directory of Open Access Journals (Sweden)

Irina GRUMEZA

2016-12-01

Full Text Available The purpose of researches conducted in the Laboratory of Food Biotechnology of the Scientific-Practical Institute of Horticulture and Food Technology was to prepare and evaluate physico-chemical andorganoleptic properties of the semi-processed ground mutton (rolls products supplemented with walnut, pump-kin, flax and grape seed cakes (10%. The prepared semi-processed products were kept in a refrigerator at thetemperature of 0 ... + 4°C for 5 days. During 72 hours of storage in refrigeration conditions it was recorded adecrease of humidity and water-binding capacity index in roll samples. Salt and fat mass fraction changedinsignificantly and remained practically at the same level. Microbiological analyzes showed no coliform bacteria,no pathogenic bacteria, including Salmonella and sulphite reducing clostridia. Mass loss as a result of heattreatment (baking in an electric oven constituted: 9.8% (rolls with walnut seed cakes, 16.3% (pumpkin, 15.9%(grapes and 46.2% (control variant, without added cake. The best organoleptic characteristics have beenrecorded by the samples with walnut seed cake, obtaining the average score of 4.66. Rezumat. Scopul cercetărilor realizate în Laboratorul de Biotehnologii Alimentare al Institutului Ştiinţifico-Practic de Horticulturăşi Tehnologii Alimentare a fost prepararea şi evaluarea proprietăţilor fizico-chimice şiorganoleptice ale semifabricatelor din carne de ovină, îmbogăţită cu adaosuri de şrot (10% din seminţe de nuci,dovleac, in şi struguri. Semifabricatele preparate (mici au fost păstrate în frigider la 0...+40C, timp de 5zile. Peparcursul păstrării în stare refrigerată timp de 72 ore s-a constatat reducerea umidităţii şi a indicelui capacităţii delegare a apei la mostrele de mici, fracţia masică de sare şi grăsime modificându-se neesenţial şi rămânând practicla acelaşi nivel. Analizele microbiologice au arătat lipsa bacteriilor coliforme, a bacteriilor patogene

Surveying the Vienna Meridian from Brno to Varaždin

Directory of Open Access Journals (Sweden)

Miljenko Solarić

2016-12-01

Full Text Available The introduction provides a brief overview of using trigonometric chains for determining meridian arc lengths in Europe, as well as their extension to trigonometric networks in order to produce contemporary accurate maps in France. After Ruđer Bošković had visited Croatian-Hungarian Queen and Roman-German Empress Maria Theresa, she ordered Jesuit Joseph Liesganig to survey the meridian from Brno (Soběšice, over Vienna and Graz to Varaždin by establishing and surveying a trigonometric chain. That distance amounts to 320 km, i.e. the difference between latitude of the starting and finishing points of the chain equaled 2° 56' 45.85''. Two baselines were measured directly between Wiener Neustadt and Neunkirchen of 6410.903 Vienna fathom (12 158.175 m and between Seyring and Glizendorf in the Moravian field (Moravské pole, Marchfeld of 6387.862 Vienna fathom (12 114.478 m. Liesganig published previous Vienna Meridian survey results in Philosophical Transactions in London in 1768 and the final results in Latin in Dimensio Graduum Meridiani Viennensis et Hungarici in 1770. His results were quickly criticized and subsequently subjected to validation. Trigonometric point Varaždin is the first and oldest trigonometric point in Croatia.

Compreender o Agir Organizacional para Construção de Capacidades Dinâmicas: uma análise exploratória

Directory of Open Access Journals (Sweden)

Luciano Munck

2015-08-01

Full Text Available http://dx.doi.org/10.5007/2175-8077.2015v17n42p131 Neste estudo, de caráter bibliográfico, inter-relaciona-se as características de um fenômeno – capacidades dinâmicas – a outro fenômeno – o agir social organizacional. O objetivo é fundamentar um modelo interpretativo do processo cíclico de construção das capacidades dinâmicas pelos agentes sociais em seu agir organizacional. A partir da discussão teórica realizada, argumenta-se que os processos de ações e de decisões realizados pelos gestores em seu agir organizacional, pautando-se pelo fator ético e racional, são elementares para a construção de um processo cíclico das capacidades dinâmicas. Considerando esse argumento, questiona-se a prerrogativa de que as organizações são dependentes de recursos fixos para enfrentarem as transformações do ambiente. Para tanto, articulou-se o entendimento de que o uso das capacidades dinâmicas internalizadas nas práticas dos agentes sociais torna-se meio para se aperfeiçoar a aprendizagem organizacional oriunda dos processos decisórios. Por fim, contribui-se com a sistematização de um modelo interpretativo do processo cíclico de construção das capacidades dinâmicas pelos agentes sociais em seu agir organizacional.

39 CFR 955.23 - Copies of papers, withdrawal of exhibits.

Science.gov (United States)

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false Copies of papers, withdrawal of exhibits. 955.23... SERVICE BOARD OF CONTRACT APPEALS § 955.23 Copies of papers, withdrawal of exhibits. (a) When books, records, papers, or documents have been received in evidence, a true copy thereof or of such part thereof...

75 FR 44163 - Antidumping and Countervailing Duty Proceedings: Electronic Filing Procedures; Administrative...

Science.gov (United States)

2010-07-28

... Central Records Unit. Any questions concerning file formatting, document conversion, access on the Web, or... manually, a party need only submit one hard copy of the submission with the Department. The Department's regulations currently require parties to submit one hard copy original and five hard copies of a public...

19 CFR 210.55 - Content of service copies.

Science.gov (United States)

2010-04-01

... 19 Customs Duties 3 2010-04-01 2010-04-01 false Content of service copies. 210.55 Section 210.55 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE ADJUDICATION AND ENFORCEMENT Temporary Relief § 210.55 Content of service copies. (a) Any...

aCNViewer: Comprehensive genome-wide visualization of absolute copy number and copy neutral variations.

Directory of Open Access Journals (Sweden)

Victor Renault

Full Text Available Copy number variations (CNV include net gains or losses of part or whole chromosomal regions. They differ from copy neutral loss of heterozygosity (cn-LOH events which do not induce any net change in the copy number and are often associated with uniparental disomy. These phenomena have long been reported to be associated with diseases and particularly in cancer. Losses/gains of genomic regions are often correlated with lower/higher gene expression. On the other hand, loss of heterozygosity (LOH and cn-LOH are common events in cancer and may be associated with the loss of a functional tumor suppressor gene. Therefore, identifying recurrent CNV and cn-LOH events can be important as they may highlight common biological components and give insights into the development or mechanisms of a disease. However, no currently available tools allow a comprehensive whole-genome visualization of recurrent CNVs and cn-LOH in groups of samples providing absolute quantification of the aberrations leading to the loss of potentially important information.To overcome these limitations, we developed aCNViewer (Absolute CNV Viewer, a visualization tool for absolute CNVs and cn-LOH across a group of samples. aCNViewer proposes three graphical representations: dendrograms, bi-dimensional heatmaps showing chromosomal regions sharing similar abnormality patterns, and quantitative stacked histograms facilitating the identification of recurrent absolute CNVs and cn-LOH. We illustrated aCNViewer using publically available hepatocellular carcinomas (HCCs Affymetrix SNP Array data (Fig 1A. Regions 1q and 8q present a similar percentage of total gains but significantly different copy number gain categories (p-value of 0.0103 with a Fisher exact test, validated by another cohort of HCCs (p-value of 5.6e-7 (Fig 2B.aCNViewer is implemented in python and R and is available with a GNU GPLv3 license on GitHub https://github.com/FJD-CEPH/aCNViewer and Docker https://hub.docker.com/r/fjdceph/acnviewer/.aCNViewer@cephb.fr.

aCNViewer: Comprehensive genome-wide visualization of absolute copy number and copy neutral variations.

Science.gov (United States)

Renault, Victor; Tost, Jörg; Pichon, Fabien; Wang-Renault, Shu-Fang; Letouzé, Eric; Imbeaud, Sandrine; Zucman-Rossi, Jessica; Deleuze, Jean-François; How-Kit, Alexandre

2017-01-01

Copy number variations (CNV) include net gains or losses of part or whole chromosomal regions. They differ from copy neutral loss of heterozygosity (cn-LOH) events which do not induce any net change in the copy number and are often associated with uniparental disomy. These phenomena have long been reported to be associated with diseases and particularly in cancer. Losses/gains of genomic regions are often correlated with lower/higher gene expression. On the other hand, loss of heterozygosity (LOH) and cn-LOH are common events in cancer and may be associated with the loss of a functional tumor suppressor gene. Therefore, identifying recurrent CNV and cn-LOH events can be important as they may highlight common biological components and give insights into the development or mechanisms of a disease. However, no currently available tools allow a comprehensive whole-genome visualization of recurrent CNVs and cn-LOH in groups of samples providing absolute quantification of the aberrations leading to the loss of potentially important information. To overcome these limitations, we developed aCNViewer (Absolute CNV Viewer), a visualization tool for absolute CNVs and cn-LOH across a group of samples. aCNViewer proposes three graphical representations: dendrograms, bi-dimensional heatmaps showing chromosomal regions sharing similar abnormality patterns, and quantitative stacked histograms facilitating the identification of recurrent absolute CNVs and cn-LOH. We illustrated aCNViewer using publically available hepatocellular carcinomas (HCCs) Affymetrix SNP Array data (Fig 1A). Regions 1q and 8q present a similar percentage of total gains but significantly different copy number gain categories (p-value of 0.0103 with a Fisher exact test), validated by another cohort of HCCs (p-value of 5.6e-7) (Fig 2B). aCNViewer is implemented in python and R and is available with a GNU GPLv3 license on GitHub https://github.com/FJD-CEPH/aCNViewer and Docker https

Bond-orientational analysis of hard-disk and hard-sphere structures.

Science.gov (United States)

Senthil Kumar, V; Kumaran, V

2006-05-28

We report the bond-orientational analysis results for the thermodynamic, random, and homogeneously sheared inelastic structures of hard-disks and hard-spheres. The thermodynamic structures show a sharp rise in the order across the freezing transition. The random structures show the absence of crystallization. The homogeneously sheared structures get ordered at a packing fraction higher than the thermodynamic freezing packing fraction, due to the suppression of crystal nucleation. On shear ordering, strings of close-packed hard-disks in two dimensions and close-packed layers of hard-spheres in three dimensions, oriented along the velocity direction, slide past each other. Such a flow creates a considerable amount of fourfold order in two dimensions and body-centered-tetragonal (bct) structure in three dimensions. These transitions are the flow analogs of the martensitic transformations occurring in metals due to the stresses induced by a rapid quench. In hard-disk structures, using the bond-orientational analysis we show the presence of fourfold order. In sheared inelastic hard-sphere structures, even though the global bond-orientational analysis shows that the system is highly ordered, a third-order rotational invariant analysis shows that only about 40% of the spheres have face-centered-cubic (fcc) order, even in the dense and near-elastic limits, clearly indicating the coexistence of multiple crystalline orders. When layers of close-packed spheres slide past each other, in addition to the bct structure, the hexagonal-close-packed (hcp) structure is formed due to the random stacking faults. Using the Honeycutt-Andersen pair analysis and an analysis based on the 14-faceted polyhedra having six quadrilateral and eight hexagonal faces, we show the presence of bct and hcp signatures in shear ordered inelastic hard-spheres. Thus, our analysis shows that the dense sheared inelastic hard-spheres have a mixture of fcc, bct, and hcp structures.

Advantage of using allele-specific copy numbers when testing for association in regions with common copy number variants.

Directory of Open Access Journals (Sweden)

Gaëlle Marenne

Full Text Available Copy number variants (CNV can be called from SNP-arrays; however, few studies have attempted to combine both CNV and SNP calls to test for association with complex diseases. Even when SNPs are located within CNVs, two separate association analyses are necessary, to compare the distribution of bi-allelic genotypes in cases and controls (referred to as SNP-only strategy and the number of copies of a region (referred to as CNV-only strategy. However, when disease susceptibility is actually associated with allele specific copy-number states, the two strategies may not yield comparable results, raising a series of questions about the optimal analytical approach. We performed simulations of the performance of association testing under different scenarios that varied genotype frequencies and inheritance models. We show that the SNP-only strategy lacks power under most scenarios when the SNP is located within a CNV; frequently it is excluded from analysis as it does not pass quality control metrics either because of an increased rate of missing calls or a departure from fitness for Hardy-Weinberg proportion. The CNV-only strategy also lacks power because the association testing depends on the allele which copy number varies. The combined strategy performs well in most of the scenarios. Hence, we advocate the use of this combined strategy when testing for association with SNPs located within CNVs.

Copying of holograms by spot scanning approach.

Science.gov (United States)

Okui, Makoto; Wakunami, Koki; Oi, Ryutaro; Ichihashi, Yasuyuki; Jackin, Boaz Jessie; Yamamoto, Kenji

2018-05-20

To replicate holograms, contact copying has conventionally been used. In this approach, a photosensitive material is fixed together with a master hologram and illuminated with a coherent beam. This method is simple and enables high-quality copies; however, it requires a large optical setup for large-area holograms. In this paper, we present a new method of replicating holograms that uses a relatively compact optical system even for the replication of large holograms. A small laser spot that irradiates only part of the hologram is used to reproduce the hologram by scanning the spot over the whole area of the hologram. We report on the results of experiments carried out to confirm the copy quality, along with a guide to design scanning conditions. The results show the potential effectiveness of the large-area hologram replication technology using a relatively compact apparatus.

Categoria etnică din perspectivă lingvistică

Directory of Open Access Journals (Sweden)

Răzvan Săftoiu

2017-03-01

Full Text Available În această lucrare, propun analiza din perspectivă lingvistică a construcției unei categorii etnice din România care este denumită prin cel puțin doi termeni: țigan și rom. Conceptul de categorie se referă la membrii unui anumit grup care se diferențiază de alte grupuri printr-un set de elemente specifice recunoscute la nivelul unei comunități mai largi. În interacțiune, indivizii apelează frecvent la categorii și la setul de trăsături pe care îl poartă o anumită categorie, deoarece este mai ușor de operat cu seturi de cunoștințe decît cu referințe pentru fiecare individ în parte. Analiza are la bază o serie de expresii și locuțiuni, proverbe și glume care au circulat (sau încă mai circulă în spațiul românesc și care au conturat, la nivelul mentalității colective, imaginea unei categorii etnice a cărei denumire (încă oscilează între doi termeni. Textele au fost grupate în funcție de diverse stereotipuri asociate categoriei etnice avute în vedere, evidențiind conotațiile peiorative ale utilizărilor termenului țigan în raport cu categoria etnică rom, o categorie „goală” de semnificație, care poate fi „umplută” cu elemente ce pot creiona o imagine pozitivă.

Re-thinking copyright through the copy in Russia

NARCIS (Netherlands)

Sezneva, O.

2013-01-01

How one copy of a film or a single is made illegal, while its identical twin is treated as legitimate? By drawing from the material collected in Russia on the illegal copying and distribution of video and musical contents, this paper moves beyond the definition of media piracy in legal terms, and

1 CFR 18.1 - Original and copies required.

Science.gov (United States)

2010-01-01

... 1 General Provisions 1 2010-01-01 2010-01-01 false Original and copies required. 18.1 Section 18.1... PROCESSING OF DOCUMENTS PREPARATION AND TRANSMITTAL OF DOCUMENTS GENERALLY § 18.1 Original and copies... agency submitting a document to be filed and published in the Federal Register shall send an original and...

Photon technology. Hard photon technology; Photon technology. Hard photon gijutsu

Energy Technology Data Exchange (ETDEWEB)

NONE

1996-03-01

Research results of hard photon technology have been summarized as a part of novel technology development highly utilizing the quantum nature of photon. Hard photon technology refers to photon beam technologies which use photon in the 0.1 to 200 nm wavelength region. Hard photon has not been used in industry due to the lack of suitable photon sources and optical devices. However, hard photon in this wavelength region is expected to bring about innovations in such areas as ultrafine processing and material synthesis due to its atom selective reaction, inner shell excitation reaction, and spatially high resolution. Then, technological themes and possibility have been surveyed. Although there are principle proposes and their verification of individual technologies for the technologies of hard photon generation, regulation and utilization, they are still far from the practical applications. For the photon source technology, the laser diode pumped driver laser technology, laser plasma photon source technology, synchrotron radiation photon source technology, and vacuum ultraviolet photon source technology are presented. For the optical device technology, the multi-layer film technology for beam mirrors and the non-spherical lens processing technology are introduced. Also are described the reduction lithography technology, hard photon excitation process, and methods of analysis and measurement. 430 refs., 165 figs., 23 tabs.

"We're still in a struggle": Diné resilience, survival, historical trauma, and healing.

Science.gov (United States)

Goodkind, Jessica R; Hess, Julia Meredith; Gorman, Beverly; Parker, Danielle P

2012-08-01

As part of a community/university collaborative effort to promote the mental health and well-being of Diné (Navajo) youth, we explored the relevance of addressing historical trauma and current structural stressors, and of building on individual and community strengths through healing and social transformation at multiple levels. Qualitative analyses of 74 ethnographic interviews with 37 Diné youth, parents, and grandparents suggested that a focus on historical trauma as a conceptual frame for behavioral health inequities, understood within the context of resilience and survival, is appropriate. Our findings also highlight the salience of current stressors such as poverty and violence exposure. We explore the fit of an historical trauma healing framework and present implications for intervention and transformation through revitalization of traditional knowledge, culturally based healing practices, intergenerational education, and social change strategies designed to eliminate social inequities.

PRODUCEREA ŞI COMERCIALIZAREA BĂUTURILOR ALCOOLICE ÎN ORAŞELE DIN RZECZPOSPOLITA ŞI ŢARA MOLDOVEI (SEC.XVI-XVII

Directory of Open Access Journals (Sweden)

Nicolae DUDNICENCO

2016-12-01

Full Text Available Articolul vizează producerea, comercializarea şi consumul băuturilor alcoolice în oraşele din Rzeczpospolita (a berii, a votcii, a miedului şi din Ţara Moldovei (a vinului, a rachiului, a berii, a brăgii în sec. XVI-XVII. Se investighează mo­dul de producere, comercializare, precum şi taxele care se percepeau pentru băuturile alcoolice în oraşele din teri­toriul dat. Producerea băuturilor alcoolice aducea venituri mari economiei oraşelor din spaţiul indicat supra.PRODUCTION AND COMMERCIALISATION OF ALCOHOLIC DRINKS IN RZECZPOSPOLITA AND MOLDOVA PRINCIPALITY CITIES (XVI-XVII C.The article targeting the production, marketing and consumption of alcoholic drinks in the cities from Rzeczpospolita (beer, vodka, mead and from Moldova (wine, spirits, beer, braga in the XVI-XVII c. It have been investigated the mode of production, sell and taxes at which were subjected the alcoholic drinks in the cities on that territory. Production of alcoholic drinks brought substantial revenues to the economy of the cities from the indicated area.

Mitochondrial DNA Copy Number in Sleep Duration Discordant Monozygotic Twins

DEFF Research Database (Denmark)

Wrede, Joanna E; Mengel-From, Jonas; Buchwald, Dedra

2015-01-01

STUDY OBJECTIVES: Mitochondrial DNA (mtDNA) copy number is an important component of mitochondrial function and varies with age, disease, and environmental factors. We aimed to determine whether mtDNA copy number varies with habitual differences in sleep duration within pairs of monozygotic twins...... structure to assess within-pair effects of sleep duration on mtDNA copy number. MEASUREMENTS AND RESULTS: Mean within-pair sleep duration difference per 24 hours was 94.3 minutes (SD 62.6 min). We found reduced sleep duration (β = 0.06; 95% CI 0.004, 0.12; P sleep efficiency (β = 0.51; 95% CI 0.......06, 0.95; P DNA copy number within twin pairs. Thus every 1-minute decrease in actigraphy-defined sleep duration was associated with a decrease in mtDNA copy number of 0.06. Likewise, a 1% decrease in actigraphy-defined sleep efficiency was associated...

Doctor Shoja-ad-Din Sheikholeslamzadeh and his Achievements

Directory of Open Access Journals (Sweden)

Ahmadreza Afshar

2015-01-01

Full Text Available Doctor Shoja-ad-Din Sheikholeslamzadeh (also known as Dr. Sheikh (1931-2014 was an outstanding orthopedic surgeon. He is credited for the establishment of the Iranian Association of Rehabilitation, Shafa Yahyaian Hospital as an Orthopedic and Rehabilitation Center, the Social Welfare Organization, Iran’s emergency dispatch center (115 and many other major projects that led to the upgrading of health care services in Iran. He also served as the Minister of Social Welfare and Minister of Health and Welfare before the Islamic revolution. The history of modern health care management and modern orthopedic surgery in Iran are indebted to the great leadership and executive abilities of Dr. Sheikh

Dinámica y control poblacional de insectos

OpenAIRE

Anabel Albornoz, Teresita

2012-01-01

Anais do I Encontro de Iniciação Científica e de Extensão da Unila - Sessão de Ciências Biológicas. Dia 05/06/12 - 08h00 às 12h00, Unila-Centro - Sala 14 - 3o Piso El presente proyecto de investigación trata de la dinámica poblacional de insectos, la relación com depre - dadores y la interacción de ambos con plantaciones de frutas. El objetivo es buscar el realismo en la fór - mula predador-presa, en relación al tiempo y al espacio, según Lotka-Volterra. Esto significa, encontrar ...

Doctor Shoja-ad-Din Sheikholeslamzadeh and his Achievements.

Science.gov (United States)

Afshar, Ahmadreza; Ziaei, Majid Eyvaz; Ahmadi, Aziz

2015-01-01

Doctor Shoja-ad-Din Sheikholeslamzadeh (also known as Dr. Sheikh) (1931-2014) was an outstanding orthopedic surgeon. He is credited for the establishment of the Iranian Association of Rehabilitation, Shafa Yahyaian Hospital as an Orthopedic and Rehabilitation Center, the Social Welfare Organization, Iran's emergency dispatch center (115) and many other major projects that led to the upgrading of health care services in Iran. He also served as the Minister of Social Welfare and Minister of Health and Welfare before the Islamic revolution. The history of modern health care management and modern orthopedic surgery in Iran are indebted to the great leadership and executive abilities of Dr. Sheikh.

25 CFR 571.13 - Copies of audit reports.

Science.gov (United States)

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Copies of audit reports. 571.13 Section 571.13 Indians... MONITORING AND INVESTIGATIONS Audits § 571.13 Copies of audit reports. (a) Each tribe shall prepare and.../or reports as a result of the audit setting forth the results of each fiscal year. The submission...

The Art of Copying: Five strategies for Transforming Originals in the Art Museum

Directory of Open Access Journals (Sweden)

Hans Dam Christensen

2017-09-01

Full Text Available This article discusses copies within the field of art museums by way of mapping strategies for copy practices. This mapping leans heavily towards parts of the wri-tings of Jacques Derrida (1930-2004. Against the backdrop of this theoretical premise, the article distinguishes five main strategies. Firstly, the copies which of-ten are considered to be typical museum copies, characterize the strategy for the disseminating relation between original and copy, that is, reproductions, magnets, etc. This strategy implies how copy practices are closely integrated into museum practices in general. Secondly, the supplementing relation between original and copy will be introduced. This strategy frames, for example, artists' citations of other works and forgeries. Both show that copy practices often lead to new originals, in principle, ad infinitum. Thirdly, this leads to the strategy for the displacing relation between original and copy which encompasses, for example, artistic reworkings of other artists' originals and conservatorial restorations. This approach partly ex-cludes the copy and partly displaces the original, while still, unavoidably, referring to the latter. In general, this strategy signifies the latent instability of the origi-nal. Fourthly, the strategy for the informational relation between original and copy will be discussed as it has a vital function in terms of talking about museum originals and copies. This is the strategy which grants the original artifacts their status as museum objects. An informational copy is just as unique as an original object of art, and at the same time, it defines the original and is itself defined by this opposition. Lastly, the strategy for the imagined relation between original and copy follows. This strategy is dependent upon several of the previous approaches, and, in addition, handles signs that exist without explicit originals, as the strategy covers copies referring to originals which have disappeared

A spatial haplotype copying model with applications to genotype imputation.

Science.gov (United States)

Yang, Wen-Yun; Hormozdiari, Farhad; Eskin, Eleazar; Pasaniuc, Bogdan

2015-05-01

Ever since its introduction, the haplotype copy model has proven to be one of the most successful approaches for modeling genetic variation in human populations, with applications ranging from ancestry inference to genotype phasing and imputation. Motivated by coalescent theory, this approach assumes that any chromosome (haplotype) can be modeled as a mosaic of segments copied from a set of chromosomes sampled from the same population. At the core of the model is the assumption that any chromosome from the sample is equally likely to contribute a priori to the copying process. Motivated by recent works that model genetic variation in a geographic continuum, we propose a new spatial-aware haplotype copy model that jointly models geography and the haplotype copying process. We extend hidden Markov models of haplotype diversity such that at any given location, haplotypes that are closest in the genetic-geographic continuum map are a priori more likely to contribute to the copying process than distant ones. Through simulations starting from the 1000 Genomes data, we show that our model achieves superior accuracy in genotype imputation over the standard spatial-unaware haplotype copy model. In addition, we show the utility of our model in selecting a small personalized reference panel for imputation that leads to both improved accuracy as well as to a lower computational runtime than the standard approach. Finally, we show our proposed model can be used to localize individuals on the genetic-geographical map on the basis of their genotype data.

Comprehensive hard materials

CERN Document Server

2014-01-01

Comprehensive Hard Materials deals with the production, uses and properties of the carbides, nitrides and borides of these metals and those of titanium, as well as tools of ceramics, the superhard boron nitrides and diamond and related compounds. Articles include the technologies of powder production (including their precursor materials), milling, granulation, cold and hot compaction, sintering, hot isostatic pressing, hot-pressing, injection moulding, as well as on the coating technologies for refractory metals, hard metals and hard materials. The characterization, testing, quality assurance and applications are also covered. Comprehensive Hard Materials provides meaningful insights on materials at the leading edge of technology. It aids continued research and development of these materials and as such it is a critical information resource to academics and industry professionals facing the technological challenges of the future. Hard materials operate at the leading edge of technology, and continued res...

Medidas dinámicas de predictibilidad en el índice s&p 500 y sus determinantes

Directory of Open Access Journals (Sweden)

Javier Humberto Ospina Holguín

2015-04-01

Full Text Available El objeto de este estudio es medir la predictibilidad del índice accionario estadounidense S&P 500 y establecer posibles determinantes de esta predictibilidad. La predictibilidad se ha estudiado ampliamente, pero en pocos casos mediante medidas dinámicas y per se, como se hace aquí. Para establecer la predictibilidad se utilizan la medida eta del campo de las redes neuronales, el valor p del test de la razón de varianzas del campo de la econometría financiera y el análisis de fluctuación sin tendencia del campo de la econofísica. Se construye un algoritmo de inversión basado en las medidas dinámicas de predictibilidad que es mejor que la estrategia de comprar y mantenerse en el periodo estudiado. Para la medida más promisoria, se establece una relación empírica entre la predictibilidad y varios factores económicos y financieros. El panorama que arroja este estudio es el de un mercado que no es estáticamente predecible, sino cuya predictibilidad evoluciona dinámicamente en el tiempo, lo cual es compatible con la hipótesis del mercado adaptativo.

Instrumentos de avaliação da postura dinâmica: aplicabilidade ao ambiente escolar

Directory of Open Access Journals (Sweden)

Matias Noll

Full Text Available INTRODUÇÃO: Para que a avaliação da postura dinâmica seja efetivada é necessário, primeiramente, conhecer os diversos instrumentos, disponíveis e validados na literatura, apropriados para esse fim. OBJETIVO: O objetivo deste artigo de revisão sistemática foi descrever, sintetizar e analisar criticamente os instrumentos encontrados na literatura que objetivem avaliar a postura dinâmica, tanto em adultos quanto em escolares, e refletir sobre a possibilidade de utilização desses métodos no ambiente escolar. MATERIAIS E MÉTODOS: Foi realizada uma busca sistemática de artigos em bases de dados (Scopus, ScienceDirect, PubMed, SciELO publicados a partir da década de 1980 e no Banco de Teses e Dissertações da Capes. As palavras-chave utilizadas na busca pelos artigos foram back, spine, back injuries, school, back school, postural hygiene program, education, child, student, posture, em combinação com as palavras-chave evaluation, assessment, measurement, e os respectivos termos em português. Os instrumentos propostos deveriam preencher os seguintes critérios: (a avaliar a postura corporal durante a realização de atividades da vida diária (AVDs; (b utilizar critérios pré-definidos de avaliação da postura dinâmica; e (c avaliar a postura a partir de observação, direta ou a partir de filmagem. RESULTADOS: Foram identificados oito artigos originais que apresentam instrumentos de avaliação da postura dinâmica, avaliando a execução de AVDs a partir de critérios biomecânicos pré-definidos por escalas numéricas; destes, apenas quatro instrumentos foram elaborados com o propósito de avaliar a execução de AVDs de escolares. CONSIDERAÇÕES FINAIS: Em geral, os instrumentos apresentam algumas limitações metodológicas, embora sejam de fácil aplicabilidade.

STUDIUL COMPLEX Al ULEIULUI VOLATIL DIN SPECIA PEROVSCHIA ATRIPLICIFOLIA BENTH.

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Maricica COLŢUN

2017-07-01

Full Text Available În lucrare sunt prezentate rezultatele unui studiu vast privind biologia, compoziția chimică, fitochimia cantitativă și calitativă a uleiului volatil din specia Perovskia atriplicifolia, care se comportă ca plantă perenă, erbacee din familia Lamiaceae. În R. Moldova nu este cercetată ca plantă aromatică şi medicinală. Are o plasticitate ecologică mare, nu are cerinţe deosebite faţă de factorii climaterici. Se utilizează pentru proprietăţile sale febrifuge, în medicină – pentru scăderea febrei, deține proprietăți culinare dar şi decorative ori de purificare a aerului.THE COMPLEX STUDY OF THE ESSENTIAL OIL OF THE SPECIESPEROVSCHIA ATRIPLICIFOLIA BENTH.The paper presents the results of a vast study on the biology, chemical composition and qualitative phytochemistry of the essential oil of the species Perovskia atriplicifolia, which behaves like a perennial, herbaceous plant in the Lamiaceae family. In theRepublic ofMoldova, it has not been investigated as an aromatic and medicinal plant. It has a high ecological plasticity and no special requirements to climatic factors. It has febrifuge properties and is used in medicine to reduce fever. Besides, this plant is used for culinary, ornamental purposes and for air purification.

44 CFR 5.85 - Authentication and attestation of copies.

Science.gov (United States)

2010-10-01

... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Authentication and attestation of copies. 5.85 Section 5.85 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT... Authentication and attestation of copies. The Administrator, Deputy Administrators, Regional Administrators...

Metodología integral y dinámica aplicada a la programación y control de proyectos

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Leonardo José Gonzalez

2012-01-01

Full Text Available Este trabajo presenta la aplicación de la metodología integral y dinámica en la programación y control dinámico de proyectos. Para esto, a partir de la metodología se desarrolla un modelo que combina redes de actividad AON (actividad en el nodo bajo los supuestos CPM, ejecución multimodo y dinámica de sistemas. El modelo se operacionaliza por medio del desarrollo de una red de programación y una red de ejecución que interactúan a través de un bucle de control. La propuesta se valida utilizando las redes de 16 actividades de la librería MRCPSP de PSPLIB. El modelo derivado de la metodología presenta ventajas significativas en los indicadores característicos en gestión de proyectos. El trabajo concluye con la propuesta de nuevas combinaciones de herramientas, que unidas a la metodología permiten abordar problemas de programación y control de proyectos con mayor variabilidad y complejidad.

Modelizaciones Dinámicas en Matemáticas. Usos del Geogebra

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Isabel Álvarez García-Mon

2012-04-01

Full Text Available El CD-ROM “Modelizaciones Dinámicas en Matemáticas. Usos del GeoGebra” es un material destinado a profesores de Matemáticas de Educación Secundaria y Bachillerato. Consta de once proyectos diferentes sobre modelización matemática, en los que, utilizando el software GeoGebra, se resuelven problemas matemáticos basados en situaciones del mundo real.

Osservazione dei fenomeni deformativi nel centro di Roma. Dall'applicazione di tecniche avanzate DInSAR, all'analisi qualitativa della natura del rumore dei dati COSMO Sky-Med

OpenAIRE

Massimo Morigi

2015-01-01

This work was created to focus the attention on a particular aspect of theequivocation (aliasing) of the measurements made with Differential SAR interferometry (DInSAR) X-band for the presence of snow. Such equivocationemerge after a careful interpretation of the results obtained through theapplication of techniques Advanced DInSAR (A-DInSAR) for the observation ofthe deformation phenomena of the monumental structures in the center ofRome. The qualitative analysis have enabled the identificat...

Pañoletas y polainas. Dinámicas de la moda en la Cuba soviética

OpenAIRE

Cabrera Arús, Maria Antonia

2015-01-01

Resumen: El texto explora el rol de las dinámicas de la moda en la consolidación del socialismo de estado de tipo soviético en Cuba. Se afirma que la moda participó de dinámicas de dominación, legitimación y control en los años 1960s y 1970s. Se sostiene que el régimen cubano promovió significados denotativos de la cultura material que conectaron de manera directa valores políticos y estilos de la moda, y se ofrecen ejemplos que acercan el estudio de este país a los estudios contemporáneos de...

O enfermeiro como coordenador de grupos: contribuições da Dinâmica de Grupo

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Carla Natalina da Silva Fernandes

2008-03-01

Full Text Available Na enfermagem a utilização do recurso grupal tem sido utilizada para trabalhar com pessoas o que exige dos profissionais um conhecimento específico, para atender aos objetivos do grupo sem causar danos aos envolvidos. O objetivo desta pesquisa foi discutir à luz do referencial teórico da Dinâmica de Grupo os atributos desejáveis para o enfermeiro como coordenador de grupos, suas possibilidades e limitações. Trata-se de uma investigação teórica, de natureza descritiva e analítica desenvolvida por meio de pesquisa bibliográfica. Consideramos como fontes bibliográficas, inicialmente, os livros clássicos de Lewin (1948, Mailhiot (1981 e Cartwright e Zander (1975 por serem as primeiras referências na construção da ciência da dinâmica de grupo e, ainda, para a discussão teórica, a contribuição de outros autores da literatura contemporânea nacional e internacional, de acordo com sua adequação ao objetivo proposto nesse trabalho. A análise das obras foi direcionada pelo interesse na busca de elementos para o alcance do objetivo proposto. Estruturamos os resultados do trabalho em três capítulos. O primeiro capítulo Dinâmica e Funcionamento de Grupo: perspectiva histórica, conceito e fundamentos, traz conceitos fundamentais sobre a origem da dinâmica de grupo e os pressupostos iniciais. Discutimos as diferentes e complementares concepções de grupo, sendo que a fundamentação teórica e filosófica do coordenador norteará o caminho da satisfação dos objetivos propostos pelo grupo. No segundo capítulo Coordenação de Grupos: fundamentos da Ciência da Dinâmica de Grupo, abordamos os aspectos da coordenação de grupo, incluindo o planejamento e várias fases que o grupo percorre no seu desenvolvimento. Discutimos ainda os fundamentos para a sistematização da atividade grupal. No último capítulo: O enfermeiro como coordenador de grupos: discutindo caminhos para a atuação na assistência, formação de

Fundamentos e métodos de medidas de energia dinâmica no SPT

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Antonio Belincanta

2000-05-01

Full Text Available Discutem-se neste trabalho os métodos disponíveis no Brasil e no exterior para a medida da energia transferida às hastes no SPT, apresentando-se inclusive registros típicos dos eventos dinâmicos correspondentes

Gestión dinámica de conocimiento organizacional

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José Francisco Mirabal

2015-08-01

Full Text Available La presente investigación propone elementos que guían la conformación de organizaciones dinámicas en conocimiento de comportamiento inteligente, a partir del desarrollo de capacidades y estructuras distintivas articuladas que agregan valor diferenciador en la organización. Para ello, se efectuó un estudio no experimental donde se aplicó un modelo mixto complejo, que consistió en una revisión documental para identificar elementos del marco estratégico-táctico de sustentación, un intercambio con expertos con los fines de determinar aspectos mediadores, socializadores de sustento cognitivo y la elaboración de un estudio proyectivo para proponer soluciones que permitan una forma ágil de construir conocimiento para la acción. En el análisis se observó, que la gestión de conocimiento está condicionada mayormente por dominios cognitivos aislados, es poco socializada, no está generalmente interrelacionada con hechos significativos internos o externos y habitualmente, la información requerida, está desagregada en sistemas aislados. Asimismo, se prevé que para asimilar la alta variabilidad del entorno dar agilidad operacional, así como también facilitar la organización interna, es imprescindible articular objetos de conocimiento mediante estructuras integradas sistémicamente para que exista interconexión ágil desde la perspectiva individual, grupal y organizacional, tanto interna como externa para inducir de manera inteligente conocimiento que en forma dinámica genere acciones acertadas en tiempo real

Las dinámicas interactivas en el ámbito universitario: el clima de aula

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Zulay Pereira-Pérez

2010-10-01

Full Text Available Recibido 28 de julio de 2009 • Aceptado 02 de diciembre de 2009 • Corregido 20 de marzo de 2010     Las relaciones interpersonales en el ámbito humano cobran vital sentido desde el nacimiento y se van conformando en los procesos de interacción y socialización. El contexto educativo no está exento de procesos comunicativos e interactivos. Es en el aula de clase, donde, de manera más específica, se pueden identificar dichos procesos. El aula puede ser entendida como el espacio físico-humano, en el cual se desarrollan dinámicas a partir de las interacciones entre el profesorado y el grupo estudiantil, los contenidos, las estrategias de aprendizaje y el clima de aula que de ello se genera; aspectos todos, que como parte de los procesos de enseñanza y de aprendizaje están presentes en el ámbito de la clase. Es interesante analizar el clima de aula y las dinámicas interactivas que en ella se desarrollan, independientemente de la edad del estudiante –ya sea que se trate de infantes, adolescentes o adultos–. En este caso particular, se analiza el clima de aula en el ámbito universitario, entendiendo que las dinámicas interactivas que en el aula se desarrollen, determinan un ambiente propicio o no, para el proceso de enseñanza y de aprendizaje, que ha de ser considerado, si se opta por una educación integral y de calidad.

Connection and Community: Diné College Emphasizes Real-World Experience in Public Health

Science.gov (United States)

Bauer, Mark

2016-01-01

The Summer Research Enhancement Program (SREP) at Diné College provides students with a solid foundation of public health research methods and includes a hands-on internship in their home community to test their newly acquired skills while enhancing the communities' health. Focusing on health issues prioritized by Navajo health leaders, from…

Role of RecA protein in untargeted UV mutagenesis of bacteriophage lambda: evidence for the requirement for the dinB gene

International Nuclear Information System (INIS)

Brotcorne-Lannoye, A.; Maenhaut-Michel, G.

1986-01-01

Untargeted UV mutagenesis of bacteriophage lambda--i.e., the increased recovery of lambda mutants when unirradiated lambda infects UV-irradiated Escherichia coli--is thought to be mediated by a transient decrease in DNA replication fidelity, generating mutations in the newly synthesized strands. Using the bacteriophage lambda cI857----lambda c mutation system, we provide evidence that the RecA protein, shown previously to be required for this mutagenic pathway, is no longer needed when the LexA protein is inactivated by mutation. We suggest that the error-prone DNA replication responsible for UV-induced untargeted mutagenesis is turned on by the presence of replication-blocking lesions in the host cell DNA and that the RecA protein is required only to derepress the relevant din gene(s). This is in contrast to mutagenesis of irradiated bacteria or irradiated phage lambda, in which activated RecA protein has a second role in mutagenesis in addition to the cleavage of the LexA protein. Among the tested din genes, the dinB gene product (in addition to the uvrA and uvrB gene products) was found to be required for untargeted mutagenesis of bacteriophage lambda. To our knowledge, a phenotype associated with the dinB gene has not been reported previously

Estimación de modelos econométricos dinámicos lineales en tiempo continuo con observaciones discretas y medidas con error

OpenAIRE

Nuño Sevilla, Luis Enrique

2004-01-01

El problema considerado en esta tesis es la estimación de los parámetros de modelos econométricos dinámicos lineales gaussianos formulados en tiempo continuo cuando las observaciones son discretas y se recogen a intervalos irregulares de tiempo. Además, se permite la posibilidad de que las observaciones difieran de las variables cuya dinámica se representa en el modelo.

ALERGENUL ARA H3, GLOBULINA DE REZERVĂ 11S DIN SEMINŢELE DE ARAHIDE 1. PROTEOLIZA LIMITATĂ CU PAPAINĂ

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Ala CHERDIVARĂ

2017-07-01

Full Text Available Proteoliza globulinei de rezervă 11S din seminţele de arahide, Ara h3, cu papaină începe cu cuscindarea secvenței C-terminale extinse a α-catenelor, care cuprinde regiunea α-helixurilor. Clivarea ulterioară a buclei dintre β-strendurile E' şi F' din partea centrală a β-barrelui din α-catene duce la formarea fragmentelor, legate cu β-catenele intacte prin legătură disulfidică, precum şi reţinute în molecula globulinei 11S parţial hidrolizată prin interacţiuni necovalente. Conform scenariului proteolizei descrise, acţiunea iniţială a papainei distruge regiunea C-terminală a α-catenelor, în care sunt prezenţi trei din cei patru determinanţi antigenici (epitopii IgE, identificaţi în globulina 11S din arahide. Astfel, gradul de alergenicitate a Ara h3 poate fi substanțial redus prin proteoliza sa limitată cu papaină.ALLERGEN ARA H3, STORAGE 11S GLOBULIN FROM PEANUT SEEDS 1. PAPAIN LIMITED PROTEOLYSISPapain proteolysis of the storage 11S globulin Ara h3 from peanut seeds starts from the detachment of an extended a-chain C-terminal sequence covering the region of a-helices. Further cleavage of a loop between b-strands E’ and F’ inside the central part of a-chain b-barrel occurs generating fragments connected with intact b-chains via a disulfide bond and those retained inside the molecule of partially hydrolyzed 11S globulin due to non-covalent interactions. In accordance with the described proteolysis scenario, the C-terminal a-chain region containing three of the four antigen determinants (IgE epitopes identified in the peanut 11S globulin is destroyed during the initial papain action. Therefore, the level of Ara h3 allergenicity can be decreased via papain limited proteolysis.

Remember Hard but Think Softly: Metaphorical Effects of Hardness/Softness on Cognitive Functions

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Jiushu Xie

2016-09-01

Full Text Available Previous studies have found that bodily stimulation, such as hardness, biases social judgment and evaluation via metaphorical association; however, it remains unclear whether bodily stimulation also affects cognitive functions, such as memory and creativity. The current study used metaphorical associations between hard and rigid and between soft and flexible in Chinese, to investigate whether the experience of hardness affected cognitive functions requiring either rigidity (memory or flexibility (creativity. In Experiment 1, we found that Chinese-speaking participants performed better at recalling previously memorized words while sitting on a hard-surface stool (the hard condition than a cushioned one (the soft condition. In Experiment 2, participants sitting on a cushioned stool outperformed those sitting on a hard-surface stool on a Chinese riddle task, which required creative/flexible thinking, but not on an analogical reasoning task, which required both rigid and flexible thinking. The results suggest the hardness experience affects cognitive functions that are metaphorically associated with rigidity and flexibility. They support the embodiment proposition that cognitive functions and representations could be grounded via metaphorical association in bodily states.

48 CFR 6302.25 - Copies of papers (Rule 25).

Science.gov (United States)

2010-10-01

... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Copies of papers (Rule 25). 6302.25 Section 6302.25 Federal Acquisition Regulations System DEPARTMENT OF TRANSPORTATION BOARD OF CONTRACT APPEALS RULES OF PROCEDURE 6302.25 Copies of papers (Rule 25). When books, records, papers, or...

Peer-to-peer computing for secure high performance data copying

International Nuclear Information System (INIS)

Hanushevsky, A.; Trunov, A.; Cottrell, L.

2001-01-01

The BaBar Copy Program (bbcp) is an excellent representative of peer-to-peer (P2P) computing. It is also a pioneering application of its type in the P2P arena. Built upon the foundation of its predecessor, Secure Fast Copy (sfcp), bbcp incorporates significant improvements performance and usability. As with sfcp, bbcp uses ssh for authentication; providing an elegant and simple working model--if you can ssh to a location, you can copy files to or from that location. To fully support this notion, bbcp transparently supports 3rd party copy operations. The program also incorporates several mechanism to deal with firewall security; the bane of P2P computing. To achieve high performance in a wide area network, bbcp allows a user to independently specify, the number of parallel network streams, tcp window size, and the file I/O blocking factor. Using these parameters, data is pipelined from source to target to provide a uniform traffic pattern that maximizes router efficiency. For improved recoverability, bbcp also keeps track of copy operations so that an operation can be restarted from the point of failure at a later time; minimizing the amount of network traffic in the event of a copy failure. Here, the authors present the bbcp architecture, it's various features, and the reasons for their inclusion

Peer-to-Peer Computing for Secure High Performance Data Copying

International Nuclear Information System (INIS)

2002-01-01

The BaBar Copy Program (bbcp) is an excellent representative of peer-to-peer (P2P) computing. It is also a pioneering application of its type in the P2P arena. Built upon the foundation of its predecessor, Secure Fast Copy (sfcp), bbcp incorporates significant improvements performance and usability. As with sfcp, bbcp uses ssh for authentication; providing an elegant and simple working model -- if you can ssh to a location, you can copy files to or from that location. To fully support this notion, bbcp transparently supports 3rd party copy operations. The program also incorporates several mechanism to deal with firewall security; the bane of P2P computing. To achieve high performance in a wide area network, bbcp allows a user to independently specify, the number of parallel network streams, tcp window size, and the file I/O blocking factor. Using these parameters, data is pipelined from source to target to provide a uniform traffic pattern that maximizes router efficiency. For improved recoverability, bbcp also keeps track of copy operations so that an operation can be restarted from the point of failure at a later time; minimizing the amount of network traffic in the event of a copy failure. Here, we preset the bbcp architecture, it's various features, and the reasons for their inclusion

75 FR 3863 - Mandatory Deposit of Published Electronic Works Available Only Online

Science.gov (United States)

2010-01-25

...., 37 CFR 202.20(b)(1) ``For purposes of this section, if a work is first published in both hard copy, i... Congress Best Edition Statement requirements pertaining to the hard copy format apply.'') Nevertheless, the... demands, the inclusion of metadata and formatting codes in deposit copies, user access to deposit copies...

Mitochondrial DNA Copy Number in Sleep Duration Discordant Monozygotic Twins.

Science.gov (United States)

Wrede, Joanna E; Mengel-From, Jonas; Buchwald, Dedra; Vitiello, Michael V; Bamshad, Michael; Noonan, Carolyn; Christiansen, Lene; Christensen, Kaare; Watson, Nathaniel F

2015-10-01

Mitochondrial DNA (mtDNA) copy number is an important component of mitochondrial function and varies with age, disease, and environmental factors. We aimed to determine whether mtDNA copy number varies with habitual differences in sleep duration within pairs of monozygotic twins. Academic clinical research center. 15 sleep duration discordant monozygotic twin pairs (30 twins, 80% female; mean age 42.1 years [SD 15.0]). Sleep duration was phenotyped with wrist actigraphy. Each twin pair included a "normal" (7-9 h/24) and "short" (sleeping twin. Fasting peripheral blood leukocyte DNA was assessed for mtDNA copy number via the n-fold difference between qPCR measured mtDNA and nuclear DNA creating an mtDNA measure without absolute units. We used generalized estimating equation linear regression models accounting for the correlated data structure to assess within-pair effects of sleep duration on mtDNA copy number. Mean within-pair sleep duration difference per 24 hours was 94.3 minutes (SD 62.6 min). We found reduced sleep duration (β = 0.06; 95% CI 0.004, 0.12; P sleep efficiency (β = 0.51; 95% CI 0.06, 0.95; P sleep duration was associated with a decrease in mtDNA copy number of 0.06. Likewise, a 1% decrease in actigraphy-defined sleep efficiency was associated with a decrease in mtDNA copy number of 0.51. Reduced sleep duration and sleep efficiency were associated with reduced mitochondrial DNA copy number in sleep duration discordant monozygotic twins offering a potential mechanism whereby short sleep impairs health and longevity through mitochondrial stress. © 2015 Associated Professional Sleep Societies, LLC.

37 CFR 350.4 - Filing and service.

Science.gov (United States)

2010-07-01

..., and one electronic copy in Portable Document Format (PDF) on compact disk (an optical data storage... electronically (i.e., by e-mail), followed by a hard copy, first-class mail of the hard copy may be used in lieu...

Screening for common copy-number variants in cancer genes.

Science.gov (United States)

Tyson, Jess; Majerus, Tamsin M O; Walker, Susan; Armour, John A L

2010-12-01

For most cases of colorectal cancer that arise without a family history of the disease, it is proposed that an appreciable heritable component of predisposition is the result of contributions from many loci. Although progress has been made in identifying single nucleotide variants associated with colorectal cancer risk, the involvement of low-penetrance copy number variants is relatively unexplored. We have used multiplex amplifiable probe hybridization (MAPH) in a fourfold multiplex (QuadMAPH), positioned at an average resolution of one probe per 2 kb, to screen a total of 1.56 Mb of genomic DNA for copy number variants around the genes APC, AXIN1, BRCA1, BRCA2, CTNNB1, HRAS, MLH1, MSH2, and TP53. Two deletion events were detected, one upstream of MLH1 in a control individual and the other in APC in a colorectal cancer patient, but these do not seem to correspond to copy number polymorphisms with measurably high population frequencies. In summary, by means of our QuadMAPH assay, copy number measurement data were of sufficient resolution and accuracy to detect any copy number variants with high probability. However, this study has demonstrated a very low incidence of deletion and duplication variants within intronic and flanking regions of these nine genes, in both control individuals and colorectal cancer patients. Copyright © 2010 Elsevier Inc. All rights reserved.

Dinámica institucional de la Representación. Individualismo y partidos en la Cámara de Diputados

Directory of Open Access Journals (Sweden)

Carlos Alberto MARQUÉS NOVAES

2009-11-01

Full Text Available RESUMEN: Determinados rasgos históricos de las instituciones políticas brasileñas -forma de gobierno y sistema electoral principalmente-inciden en la dinámica interna del Congreso. El autor analiza como se desarrollan las diversas actividades vinculadas a la producción legislativa y pone en evidencia una dinámica individualista que anula la posibilidad de desarrollar estrategias cooperativas. No obstante, el estudio de las votaciones sobre determinadas cuestiones niega la hipótesis de que esta dinámica elimine la existencia de un posicionamiento ideológico dentro del Congreso sobre el eje izquierda-derecha.ABSTRACT: It is analyzed how specific historical features of brazilean political institutions -specially, type of government and electoral system- influence in the internal dynamic of Congress. The author analyzes the process of legislative production and underlines an individualistic dynamic which cancel the possibility to develop cooperative strategies. However, the study possibility to develop cooperative strategies. However, the study of votings about specific questions denyes the hypothesis which sets up that this kind of dynamic eliminates the existence of an ideological position inside the Congress in the axis left-right.

Una aproximación metodológica para el modelamiento organizacional bajo un enfoque de dinámica de sistemas

OpenAIRE

Arango Serna, Martin Darío

1997-01-01

EI objetivo de este trabajo es elaborar unas paulas metodológicas basadas en dinámica de sistemas que permitan experimentar estrategias de cambia en las organizaciones. Es un proyecto de investigaci6n que surge ante la necesidad de involucrar en los procesos del modelamiento organizacional el pensamiento sistémico conjuntamente con la dinámica de sistemas, como una herramienta ágil para la toma de decisiones en las políticas gerenciales del mundo empresarial moderno. EI pensamiento de...

Desempenho do equilíbrio dinâmico de escolares ouvintes e com perda auditiva sensorioneural

Directory of Open Access Journals (Sweden)

Renato de Souza Melo

2014-12-01

Full Text Available Introdução: O equilíbrio corporal humano é regulado pela atuação sensorial do sistema vestibular, situado na orelha interna. Crianças com perda auditiva sensorioneural podem apresentar alterações no sistema vestibular e, consequentemente, no equilíbrio corporal, em decorrência da lesão na orelha interna. Objetivos: Avaliar o equilíbrio dinâmico em escolares ouvintes e com perda auditiva sensorioneural e comparar os dados entre os grupos considerando os sexos e as faixas etárias. Métodos: Estudo de corte transversal, que avaliou 96 escolares, sendo 48 ouvintes e 48 com perda auditiva sensorioneural, de ambos os sexos, na faixa etária entre sete e 18 anos. A avaliação do equilíbrio dinâmico foi realizada por meio do teste de Babinski-Weil e do teste de Fukuda. Para a análise dos dados foi utilizado o teste do qui-quadrado de Pearson, tendo em vista a distribuição de normalidade dos dados. Resultados: Os escolares com perda auditiva apresentaram maior ocorrência de alterações no equilíbrio dinâmico comparado aos ouvintes: teste de Babinski-Weil e teste de Fukuda: (p<0,001. A mesma diferença foi observada quando os voluntários foram agrupados pelos sexos: feminino e masculino: teste de Babinski-Weil e teste de Fukuda: (p<0,001. Estratificando-se pelas faixas etárias, os resultados apontaram diferenças, entre todos os grupos etários avaliados: teste de Babinski-Weil: sete a 14 anos: (p<0,001 e 15-18 anos: (p= 0,004, teste de Fukuda: sete a 18 anos: (p<0,001. Conclusão: Os escolares com perda auditiva apresentaram maior ocorrência de alterações no equilíbrio dinâmico que os ouvintes do mesmo sexo e faixa etária.

DNA copy number, including telomeres and mitochondria, assayed using next-generation sequencing

Directory of Open Access Journals (Sweden)

Jackson Stuart

2010-04-01

Full Text Available Abstract Background DNA copy number variations occur within populations and aberrations can cause disease. We sought to develop an improved lab-automatable, cost-efficient, accurate platform to profile DNA copy number. Results We developed a sequencing-based assay of nuclear, mitochondrial, and telomeric DNA copy number that draws on the unbiased nature of next-generation sequencing and incorporates techniques developed for RNA expression profiling. To demonstrate this platform, we assayed UMC-11 cells using 5 million 33 nt reads and found tremendous copy number variation, including regions of single and homogeneous deletions and amplifications to 29 copies; 5 times more mitochondria and 4 times less telomeric sequence than a pool of non-diseased, blood-derived DNA; and that UMC-11 was derived from a male individual. Conclusion The described assay outputs absolute copy number, outputs an error estimate (p-value, and is more accurate than array-based platforms at high copy number. The platform enables profiling of mitochondrial levels and telomeric length. The assay is lab-automatable and has a genomic resolution and cost that are tunable based on the number of sequence reads.

Dinâmica de redes de osciladores de Fitzhugh-Nagumo

OpenAIRE

Santos, Juliana Vicente dos

2013-01-01

O modelo de Fitzhugh-Nagumo é composto originalmente por um sistema de duas equações diferenciais não-lineares, que simulam o comportamento de condução do impulso nervoso através da membrana neural. Neste trabalho estudamos numericamente o comportamento dinâmico de redes de neurônios acoplados, modeladas pelas equações de Fitzhugh-Nagumo. Consideramos redes de dois, três e quatro neurônios acoplados unidirecionalmente e bidirecionalmente, para as quais foram construídos espaços de parâmetros ...

Hard coal; Steinkohle

Energy Technology Data Exchange (ETDEWEB)

Loo, Kai van de; Sitte, Andreas-Peter [Gesamtverband Steinkohle e.V., Herne (Germany)

2013-04-01

The year 2012 benefited from a growth of the consumption of hard coal at the national level as well as at the international level. Worldwide, the hard coal still is the number one energy source for power generation. This leads to an increasing demand for power plant coal. In this year, the conversion of hard coal into electricity also increases in this year. In contrast to this, the demand for coking coal as well as for coke of the steel industry is still declining depending on the market conditions. The enhanced utilization of coal for the domestic power generation is due to the reduction of the nuclear power from a relatively bad year for wind power as well as reduced import prices and low CO{sub 2} prices. Both justify a significant price advantage for coal in comparison to the utilisation of natural gas in power plants. This was mainly due to the price erosion of the inexpensive US coal which partly was replaced by the expansion of shale gas on the domestic market. As a result of this, the inexpensive US coal looked for an outlet for sales in Europe. The domestic hard coal has continued the process of adaptation and phase-out as scheduled. Two further hard coal mines were decommissioned in the year 2012. RAG Aktiengesellschaft (Herne, Federal Republic of Germany) running the hard coal mining in this country begins with the preparations for the activities after the time of mining.

Kioo cha Lugha: Submissions

African Journals Online (AJOL)

AFRICAN JOURNALS ONLINE (AJOL) · Journals · Advanced Search · USING AJOL ... Submissions should be made in soft or hard copy, by either sending two hard copies to IKS mailing address or sending soft copy to iks@udsm.ac.tz or ...

30 CFR 75.1720-1 - Distinctively colored hard hats, or hard caps; identification for newly employed, inexperienced...

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Distinctively colored hard hats, or hard caps... STANDARDS-UNDERGROUND COAL MINES Miscellaneous § 75.1720-1 Distinctively colored hard hats, or hard caps; identification for newly employed, inexperienced miners. Hard hats or hard caps distinctively different in color...

Comportamiento mecánico y dinámico de una mezcla asfáltica con adición de fibras

Directory of Open Access Journals (Sweden)

Oscar Javier Reyes Ortiz

2005-01-01

Full Text Available El artículo refiere el análisis experimental en el laboratorio, del efecto de la adición de fibras de polipropileno por vía seca (reemplazo de material granular por fibra sobre las propiedades mecánicas y dinámicas de una mezcla. Inicialmente se caracteriza el material granular y asfalto CA60/70, se realiza el diseño de la mezcla asfáltica de granulometría 0/10 (IDU RSV 2002 y asfalto de acuerdo con la metodología Marshall; se evalúa el efecto de fibras sobre las propiedades mecánicas mediante la evaluación de la estabilidad y fluencia, y dinámicamente por su valor de deformación permanente y modulo dinámico. Los resultados muestran un efecto positivo de las fibras en la modificación de la mezcla asfáltica. El modulo dinámico aumenta en un 45% promedio en un porcentaje de adición de 0.60%; la deformación permanente disminuye en 27.6% para una adición de fibras de 0.60% y 48.8% para la adición de fibras de 0.75%, respectivamente. Este comportamiento refleja otra alternativa eficaz para mejorar la mezcla asfáltica, aumentando la resistencia a la disgregación por efecto abrasivo del tráfico y retardando el inicio y propagación del agrietamiento por ahuellamiento

30 CFR 77.1710-1 - Distinctively colored hard hats or hard caps; identification for newly employed, inexperienced...

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Distinctively colored hard hats or hard caps... Distinctively colored hard hats or hard caps; identification for newly employed, inexperienced miners. Hard hats or hard caps distinctively different in color from those worn by experienced miners shall be worn at...

Incidental copy-number variants identified by routine genome testing in a clinical population

Science.gov (United States)

Boone, Philip M.; Soens, Zachry T.; Campbell, Ian M.; Stankiewicz, Pawel; Cheung, Sau Wai; Patel, Ankita; Beaudet, Arthur L.; Plon, Sharon E.; Shaw, Chad A.; McGuire, Amy L.; Lupski, James R.

2013-01-01

Purpose Mutational load of susceptibility variants has not been studied on a genomic scale in a clinical population, nor has the potential to identify these mutations as incidental findings during clinical testing been systematically ascertained. Methods Array comparative genomic hybridization, a method for genome-wide detection of DNA copy-number variants, was performed clinically on DNA from 9,005 individuals. Copy-number variants encompassing or disrupting single genes were identified and analyzed for their potential to confer predisposition to dominant, adult-onset disease. Multigene copy-number variants affecting dominant, adult-onset cancer syndrome genes were also assessed. Results In our cohort, 83 single-gene copy-number variants affected 40 unique genes associated with dominant, adult-onset disorders and unrelated to the patients’ referring diagnoses (i.e., incidental) were found. Fourteen of these copy-number variants are likely disease-predisposing, 25 are likely benign, and 44 are of unknown clinical consequence. When incidental copy-number variants spanning up to 20 genes were considered, 27 copy-number variants affected 17 unique genes associated with dominant, adult-onset cancer predisposition. Conclusion Copy-number variants potentially conferring susceptibility to adult-onset disease can be identified as incidental findings during routine genome-wide testing. Some of these mutations may be medically actionable, enabling disease surveillance or prevention; however, most incidentally observed single-gene copy-number variants are currently of unclear significance to the patient. PMID:22878507

The double copy: gravity from gluons

Science.gov (United States)

White, C. D.

2018-04-01

Three of the four fundamental forces in nature are described by so-called gauge theories, which include the effects of both relativity and quantum mechanics. Gravity, on the other hand, is described by General Relativity, and the lack of a well-behaved quantum theory - believed to be relevant at the centre of black holes, and at the Big Bang itself - remains a notorious unsolved problem. Recently a new correspondence, the double copy, has been discovered between scattering amplitudes (quantities related to the probability for particles to interact) in gravity, and their gauge theory counterparts. This has subsequently been extended to other quantities, providing gauge theory analogues of e.g. black holes. We here review current research on the double copy, and describe some possible applications.

Educação para o uso da internet - uma abordagem através das dinâmicas de grupo

OpenAIRE

Tinoco, Rui

2013-01-01

Coletânea de dinâmicas de grupo que aborda o tema de um uso saudável da interenet. Através de diversas perspetivas e temas aborda-se várias áreas e práticas usuais. As dinâmicas de grupo destinam-se não apenas aos mais novos mas também a professores e educadores em geral. A obra pretende assim ser uma ferramenta para todo aquele que pretenda estudar e intervir sobre a temática do uso saudável da internet.

Video copy protection and detection framework (VPD) for e-learning systems

Science.gov (United States)

ZandI, Babak; Doustarmoghaddam, Danial; Pour, Mahsa R.

2013-03-01

This Article reviews and compares the copyright issues related to the digital video files, which can be categorized as contended based and Digital watermarking copy Detection. Then we describe how to protect a digital video by using a special Video data hiding method and algorithm. We also discuss how to detect the copy right of the file, Based on expounding Direction of the technology of the video copy detection, and Combining with the own research results, brings forward a new video protection and copy detection approach in terms of plagiarism and e-learning systems using the video data hiding technology. Finally we introduce a framework for Video protection and detection in e-learning systems (VPD Framework).

Convergencia, divergencia y estratificación. Estudio comparativo de la dinámica de crecimiento de la manufactura en los municipios mexicanos y los condados estadunidenses

Directory of Open Access Journals (Sweden)

Rodolfo Cermeño

2009-01-01

Full Text Available En este artículo se analiza la dinámica del valor agregado manufacturero per capita como proxy del ingreso per capita de los municipios de México y condados de Estados Unidos. Específicamente, se busca determinar si existe convergencia (absoluta o condicional, divergencia o estratificación. Se utiliza un modelo de panel dinámico sin regresores exógenos y se considera el problema del sesgo en este contexto específico. En general se concluye que la dinámica del valor agregado per capita de los condados de Estados Unidos muestra convergencia condicional y poca dispersión de sus estados estacionarios. En cambio, en el caso de México se encuentra una dinámica congruente con crecimiento estratificado. El estudio también encuentra que el crecimiento de la manufactura en los condados de EEUU y los municipios de México diverge en el tiempo.

Does Visual Attention Span Relate to Eye Movements during Reading and Copying?

Science.gov (United States)

Bosse, Marie-Line; Kandel, Sonia; Prado, Chloé; Valdois, Sylviane

2014-01-01

This research investigated whether text reading and copying involve visual attention-processing skills. Children in grades 3 and 5 read and copied the same text. We measured eye movements while reading and the number of gaze lifts (GL) during copying. The children were also administered letter report tasks that constitute an estimation of the…

Photon technology. Hard photon technology; Photon technology. Hard photon gijutsu

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-03-01

For the application of photon to industrial technologies, in particular, a hard photon technology was surveyed which uses photon beams of 0.1-200nm in wavelength. Its features such as selective atom reaction, dense inner shell excitation and spacial high resolution by quantum energy are expected to provide innovative techniques for various field such as fine machining, material synthesis and advanced inspection technology. This wavelength region has been hardly utilized for industrial fields because of poor development of suitable photon sources and optical devices. The developmental meaning, usable time and issue of a hard photon reduction lithography were surveyed as lithography in ultra-fine region below 0.1{mu}m. On hard photon analysis/evaluation technology, the industrial use of analysis, measurement and evaluation technologies by micro-beam was viewed, and optimum photon sources and optical systems were surveyed. Prediction of surface and surface layer modification by inner shell excitation, the future trend of this process and development of a vacuum ultraviolet light source were also surveyed. 383 refs., 153 figs., 17 tabs.

Obtención de Modelos Borrosos Interpretables de Procesos Dinámicos

Directory of Open Access Journals (Sweden)

Juan Contreras Montes

2008-07-01

Full Text Available Resumen: En este artículo se presenta una novedosa metodología para la construcción de modelos borrosos lingüísticamente interpretables, a partir de datos de entrada y salida, de procesos dinámicos. Se describe una sencilla técnica de agrupamiento para construcción de las reglas borrosas, así como el empleo de mínimos cuadrados para ajuste de consecuentes. Para garantizar la interpretabilidad del modelo borroso la partición de los antecedentes emplea conjuntos triangulares con interpolación de 0.5. El aspecto más promisorio en nuestra propuesta consiste en alcanzar una buena precisión sin sacrificar la interpretabilidad del sistema borroso ni recurrir a otras técnicas de inteligencia artificial. Se presentan aplicaciones a problemas o conjuntos de datos ampliamente conocidos (benchmark classic como la cámara de gas de Box-Jenkins, la serie caótica de Mackey Glass y la dinámica de cabeceo de un helicóptero a escala, y se comparan los resultados con aquellos obtenidos por otros autores que emplean técnicas diferentes. Palabras clave: identificación, agrupamiento, mínimos cuadrados, modelo borroso, interpretabilidad

Programação dinâmica aplicada a finanças

Directory of Open Access Journals (Sweden)

Tara Keshar Nanda Baídya

1997-12-01

Full Text Available Este artigo mostra a aplicação da programação dinâmica estocástica e o seu uso em Finanças. Um dos objetivos mais usuais da teoria financeira é determinar a trajetória ou caminho ótimo para determinada variável. Brennan e Schwartz (1985 analisaram economicamente o investimento na exploração de um recurso mineral. Determinaram o valor do projeto e o instante ótimo de realizar o investimento. Para tal, usaram os conceitos da teoria das opções e técnicas de avaliação por arbitragem. Este artigo obtém o mesmo modelo usando a programação dinâmica e os conceitos de finanças em tempo contínuoThis paper shows the dynamic programming approach related to Finance Theory. We exhibit how to construct the optimal path, one of the most important aims in the Finance. Brennan and Shwartz (1985 derived their model to evaluate a project of mining using option pricing theory and arbitrage approach. This is an use of option theory to evaluate a real project. Here we obtain the same model as an example, using stochastic dynamic programming

Novo desenvolvimentismo e dinâmica urbano-regional no Brasil (2004-2012

Directory of Open Access Journals (Sweden)

Hipólita Siqueira

2015-01-01

Full Text Available As mudanças no contexto nacional e internacional impuseram novas questões ao debate sobre a dinâmica urbano-regional brasileira. Dentre elas, o aprofundamento da inserção internacional do País, tendo como base seu potencial de recursos naturais e sua articulação com o "efeito-China" na reconfiguração das relações internacionais, e o processo de desindustrialização, decorrente da especialização produtiva regressiva e da apreciação da taxa de câmbio. O objetivo deste artigo é examinar as lin-has gerais da dinâmica urbano-regional no âmbito das transformações na economia e sociedade brasileiras desde os anos 1980, especialmente no período pós-2004, em que ocorre uma retomada do crescimento econômico e dos gastos estatais. Entende-se que tal análise enfrenta desafios teórico-metodológicos importantes, sendo necessário o resgate de referenciais analíticos, como o da divisão espacial do trabalho para o entendimento das desigualdades regionais, e a (reformulação da questão regional brasileira.

Standardization work by ASTM and DIN concerning test methods for metallic materials - comparative assessment with regard for practice

International Nuclear Information System (INIS)

Gerischer, K.

1986-01-01

The article explains the significant role of ASTM and marks out basic elements of the specification system of ASTM standards. Usefulness in practice is taken as the main criterion for the subsequent comparison of ASTM or DIN activities and procedures, and results, for standardization in the field of test methods for metallic materials. The main differences are shown to exist with regard to tropicality of test standards, presentation of useful information and background knowledge, and importance attached to formal questions. ASTM standardization work is shown to be more up-to-date, contain more information, and to be less concerned with formal matters. A closer cooperation between ASTM and DIN is strongly recommended. (orig.) [de

Gaisma un krāsa sabiedriskās ēdināšanas telpās

OpenAIRE

Cvetkova, Diāna

2015-01-01

Diplomdarbā „Gaisma un krāsa sabiedriskās ēdināšanas telpās” autore analizē informāciju par apgaismojuma un krāsas lomām sabiedriskās ēdināšanas telpās. Labākam priekšstatam autore detāli apraksta to, kā apgaismojums un krāsa var izmainīt telpu un ietekmēt cilvēka psiholoģisko stāvokli un noskaņojumu, kā arī, kā noteiktas krasas apgaismojums var izmainīt ēdiena krāsu, tādējādi ietekmējot mūsu ēstgribu. Empiriskā daļā autore analizē interjerus kafejnīcās unrestorānos, kas atrodas Rīgas pi...

Thermodynamic perturbation theory for fused hard-sphere and hard-disk chain fluids

International Nuclear Information System (INIS)

Zhou, Y.; Hall, C.K.; Stell, G.

1995-01-01

We find that first-order thermodynamic perturbation theory (TPT1) which incorporates the reference monomer fluid used in the generalized Flory--AB (GF--AB) theory yields an equation of state for fused hard-sphere (FHS) chain fluids that has accuracy comparable to the GF--AB and GF--dimer--AC theories. The new TPT1 equation of state is significantly more accurate than other extensions of the TPT1 theory to FHS chain fluids. The TPT1 is also extended to two-dimensional fused hard-disk chain fluids. For the fused hard-disk dimer fluid, the extended TPT1 equation of state is found to be more accurate than the Boublik hard-disk dimer equation of state. copyright 1995 American Institute of Physics

Mapping Two-Dimensional Deformation Field Time-Series of Large Slope by Coupling DInSAR-SBAS with MAI-SBAS

Directory of Open Access Journals (Sweden)

Liming He

2015-09-01

Full Text Available Mapping deformation field time-series, including vertical and horizontal motions, is vital for landslide monitoring and slope safety assessment. However, the conventional differential synthetic aperture radar interferometry (DInSAR technique can only detect the displacement component in the satellite-to-ground direction, i.e., line-of-sight (LOS direction displacement. To overcome this constraint, a new method was developed to obtain the displacement field time series of a slope by coupling DInSAR based small baseline subset approach (DInSAR-SBAS with multiple-aperture InSAR (MAI based small baseline subset approach (MAI-SBAS. This novel method has been applied to a set of 11 observations from the phased array type L-band synthetic aperture radar (PALSAR sensor onboard the advanced land observing satellite (ALOS, spanning from 2007 to 2011, of two large-scale north–south slopes of the largest Asian open-pit mine in the Northeast of China. The retrieved displacement time series showed that the proposed method can detect and measure the large displacements that occurred along the north–south direction, and the gradually changing two-dimensional displacement fields. Moreover, we verified this new method by comparing the displacement results to global positioning system (GPS measurements.

29 CFR 1921.17 - Service; copies of documents and pleadings.

Science.gov (United States)

2010-07-01

... 29 Labor 7 2010-07-01 2010-07-01 false Service; copies of documents and pleadings. 1921.17 Section 1921.17 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION... LONGSHOREMEN'S AND HARBOR WORKERS' COMPENSATION ACT Miscellaneous § 1921.17 Service; copies of documents and...

Systematic biases in DNA copy number originate from isolation procedures

NARCIS (Netherlands)

van Heesch, S.; Mokry, M.; Boskova, V.; Junker, W.; Mehon, R.; Toonen, P.; de Bruijn, E.; Shull, J.D.; Aitman, T.J.; Cuppen, E.; Guryev, V.

2013-01-01

BACKGROUND: The ability to accurately detect DNA copy number variation in both a sensitive and quantitative manner is important in many research areas. However, genome-wide DNA copy number analyses are complicated by variations in detection signal. RESULTS: While GC content has been used to correct

Conservatism and "copy-if-better" in chimpanzees (Pan troglodytes).

Science.gov (United States)

van Leeuwen, Edwin J C; Call, Josep

2017-05-01

Social learning is predicted to evolve in socially living animals provided the learning process is not random but biased by certain socio-ecological factors. One bias of particular interest for the emergence of (cumulative) culture is the tendency to forgo personal behaviour in favour of relatively better variants observed in others, also known as the "copy-if-better" strategy. We investigated whether chimpanzees employ copy-if-better in a simple token-exchange paradigm controlling for individual and random social learning. After being trained on one token-type, subjects were confronted with a conspecific demonstrator who either received the same food reward as the subject (control condition) or a higher value food reward than the subject (test condition) for exchanging another token-type. In general, the chimpanzees persisted in exchanging the token-type they were trained on individually, indicating a form of conservatism consistent with previous studies. However, the chimpanzees were more inclined to copy the demonstrator in the test compared to the control condition, indicating a tendency to employ a copy-if-better strategy. We discuss the validity of our results by considering alternative explanations and relate our findings to the emergence of cumulative culture.

Dinâmica familiar: percepção de famílias de sobreviventes de câncer de mama Dinámica familiar: percepción de familias de sobrevivientes de cancer de mama Family dynamics: perceptions of breast cancer survivor's families

Directory of Open Access Journals (Sweden)

Raquel Gabrielli Biffi

2009-03-01

Full Text Available O estudo teve como objetivo identificar as percepções de familiares sobre a dinâmica de suas famílias após o câncer de mama em um dos seus membros. Estudo de abordagem qualitativa que tomou como referencial teórico o modelo de funcionamento familiar saudável proposto por Barnhill (1979. Participaram 23 familiares constituintes de 10 famílias. Os dados foram coletados, no período de maio a junho de 2002, por meio de entrevistas, e submetidos à análise de conteúdo. Os resultados revelaram aspectos positivos na dinâmica das famílias. A percepção dos processos de identidade, através da individuação e mutualidade, favoreceram a compreensão da dinâmica familiar. Os achados mostraram que o câncer de mama tem a capacidade de provocar alterações na família, e esta se utilizou dos potenciais de cada membro em particular na busca da estabilidade familiar.El estudio objetiva identificar las percepciones de familiares sobre la dinámica de sus familias, con cáncer de mama en uno de sus miembros. Estudio de abordaje cualitativo que tomó como referencial teórico el modelo de funcionamiento familiar saludable de Barnhill (1979. Participaron 23 familiares constituyentes de 10 familias. Los datos fueron obtenidos mediante entrevistas y sometidos a análisis de contenido. Los resultados revelaron aspectos positivos en la dinámica de las familias. La percepción de los procesos de identidad, a través de la individualización y mutualidad, favoreció la comprensión de la dinámica familiar. Según los resultados, el cáncer de mama tiene la capacidad de provocar alteraciones en la familia; por otro lado, éstas se utilizaron de los potenciales de cada miembro, en particular, en la búsqueda de la estabilidad familiar.The aim of this study was to identify the family members´ perceptions of their family dynamics, after breast cancer in one of its members. The study used a qualitative approach based on the theoretical model of healthy

Prospectiva de la cadena Productiva de mango bajo el enfoque dinámico

Directory of Open Access Journals (Sweden)

Juan Pablo Tribín-Rivera

2014-01-01

Full Text Available El propósito del presente documento de investigación, es relacionar los resultados del análisis prospectivo de la cadena productiva de mango en la Provincia del Tequendama – Cundinamarca por medio de dinámica de sistemas, con el fin de compararla desde distintos escenarios; mercado interno frente al mercado externo, y así poder determinar el escenario prospectivo más conveniente para los productores. De igual forma se proponen políticas que mejoren las condiciones de los productores de la región y se relaciona el modelo de simulación por dinámica de sistemas, que puede ser utilizado en diferentes cadenas productivas. La construcción del modelo de simulación se desarrolló con base en las experiencias adquiridas por medio de visitas de campo, recolección de información primaria y secundaria, y la colaboración de expertos que participan, directa o indirectamente, en dicha cadena productiva, enmarcadas bajo el proyecto de investigación titulado “Mercado prospectivo del mango: Comparativo entre el mercado interno y el mercado externo para la Provincia del Tequendama – Cundinamarca”

MECANISMUL DE PROTEOLIZĂ A FICOCIANINEI, PROTEINEI BIOACTIVE DIN SPIRULINĂ SUB ACŢIUNEA PAPAINEI

Directory of Open Access Journals (Sweden)

Angela RUDAKOVA

2016-02-01

Full Text Available Elaborarea unor procedee de obţinere a peptidelor bioactive din ficocianină prin intermediul hidrolizei proteolitice prezintă un interes sporit pentru cercetători în contextul utilizării acestora în calitate de remedii anticancer şi pentru alte proprietăţi terapeutice. Peptidele derivate din ficocianină ar putea manifesta proprietăţi terapeutice mult mai pronunţate comparativ cu ficocianina. În prezenta lucrare sunt studiate dinamica proteolizei ficocianinei cu papaina şi mecanismul de hidroliză a acestei proteine.Mechanism of proteolysis of C-phycocyanin, bioactive protein from Spirulina, under the action of papainThe elaboration of the procedures of obtaining of bioactive peptides derived from phycocyanin, as a result of it proteolytic hydrolysis presents great interest for researchers in the terms of theirs use as anti-cancer drugs and for other therapeutic properties. It can be assumed that peptides derived from phycocyanin could manifest more pronounced therapeutic effects compared to phycocyanin. Dynamics of phycocyanin proteolisis by papain, as well as mechanism of phycocyanin hydrolysis were studied in the present work. 

Scattering on plane waves and the double copy

Science.gov (United States)

Adamo, Tim; Casali, Eduardo; Mason, Lionel; Nekovar, Stefan

2018-01-01

Perturbatively around flat space, the scattering amplitudes of gravity are related to those of Yang–Mills by colour-kinematic duality, under which gravitational amplitudes are obtained as the ‘double copy’ of the corresponding gauge theory amplitudes. We consider the question of how to extend this relationship to curved scattering backgrounds, focusing on certain ‘sandwich’ plane waves. We calculate the 3-point amplitudes on these backgrounds and find that a notion of double copy remains in the presence of background curvature: graviton amplitudes on a gravitational plane wave are the double copy of gluon amplitudes on a gauge field plane wave. This is non-trivial in that it requires a non-local replacement rule for the background fields and the momenta and polarization vectors of the fields scattering on the backgrounds. It must also account for new ‘tail’ terms arising from scattering off the background. These encode a memory effect in the scattering amplitudes, which naturally double copies as well.

La dinámica pendular de la regionalización de la universidad en Argentina

Directory of Open Access Journals (Sweden)

Claudio Antonio Rama Vitale

2014-11-01

Full Text Available El artículo analiza la dinámica de construcción del sistema de educación superior pública en Argentina atendiendo a las dimensiones de su regionalización y explorando  las tensiones regionales alrededor de sus construcción. Visualiza bajos niveles de diferenciación institucional y de competencia institucional, pero indica las complejidades de esa diferenciación regional, el carácter no resuelto políticamente de tales procesos, y como su dinámica ha estado asociada a procesos político ideológicos. La regionalización de la educación superior muestra múltiples expresiones, pero donde la dominante ha sido la tensión entre la construcción de  espacios de poder y de desarrollo académico a escala local frente al objetivo desde los ámbitos nacionales de regular nacionalmente la educación superior.  

Capacidades dinámicas que influyen en la operación de la Red de Turismo de La Candelaria

OpenAIRE

Gutiérrez Rodríguez, Alejandro Javier

2013-01-01

El desarrollo de la presente investigación, centra su atención en las capacidades dinámicas que influyen en la operación de la Red de Turismo de La Candelaria de Bogotá. Para este fin, se realizó una encuesta a 100 directivos o dueños de las empresas que conforman dicha red, y que es una muestra significativa para los propósitos de la investigación, puesto que permite describir a nivel de la empresa y a nivel de la red, la influencia de las capacidades dinámicas de absorción, adaptación e inn...

Hard-on-hard lubrication in the artificial hip under dynamic loading conditions.

Directory of Open Access Journals (Sweden)

Robert Sonntag

Full Text Available The tribological performance of an artificial hip joint has a particularly strong influence on its success. The principle causes for failure are adverse short- and long-term reactions to wear debris and high frictional torque in the case of poor lubrication that may cause loosening of the implant. Therefore, using experimental and theoretical approaches models have been developed to evaluate lubrication under standardized conditions. A steady-state numerical model has been extended with dynamic experimental data for hard-on-hard bearings used in total hip replacements to verify the tribological relevance of the ISO 14242-1 gait cycle in comparison to experimental data from the Orthoload database and instrumented gait analysis for three additional loading conditions: normal walking, climbing stairs and descending stairs. Ceramic-on-ceramic bearing partners show superior lubrication potential compared to hard-on-hard bearings that work with at least one articulating metal component. Lubrication regimes during the investigated activities are shown to strongly depend on the kinematics and loading conditions. The outcome from the ISO gait is not fully confirmed by the normal walking data and more challenging conditions show evidence of inferior lubrication. These findings may help to explain the differences between the in vitro predictions using the ISO gait cycle and the clinical outcome of some hard-on-hard bearings, e.g., using metal-on-metal.

O ciclo do café durante a República Velha: uma análise com a abordagem de dinâmica de sistemas

Directory of Open Access Journals (Sweden)

Thiago Caliari

2011-05-01

Full Text Available O objetivo deste trabalho é fazer uma análise sistêmica da dinâmica da produção cafeeira no Brasil com foco no período 1900-1930. A motivação para abordar a questão sob a ótica da dinâmica de sistemas (system dynamics é que essa metodologia é especialmente adequada para modelar processos sujeitos à complexidade dinâmica, como os ciclos de produção de commodities. Mostrar-se-á que modelar e simular a dinâmica da produção de café no Brasil com essa metodologia permite, em primeiro lugar, realizar experimentos contra-factuais que possibilitam avaliar quantitativamente o efeito de políticas de defesa de preços, como as políticas de valorização, complementando a já extensa e rica literatura sobre o assunto. Em segundo lugar, será sugerido que abordar a questão sob esta ótica ajuda a extrair insights de política não apenas para o café como para outras commodities, das quais o Brasil ainda depende de forma importante para manter o equilíbrio em suas contas externas.

Remember Hard But Think Softly: Metaphorical Effects of Hardness/Softness on Cognitive Functions

Science.gov (United States)

Xie, Jiushu; Lu, Zhi; Wang, Ruiming; Cai, Zhenguang G.

2016-01-01

Previous studies have found that bodily stimulation, such as hardness biases social judgment and evaluation via metaphorical association; however, it remains unclear whether bodily stimulation also affects cognitive functions, such as memory and creativity. The current study used metaphorical associations between “hard” and “rigid” and between “soft” and “flexible” in Chinese, to investigate whether the experience of hardness affects cognitive functions whose performance depends prospectively on rigidity (memory) and flexibility (creativity). In Experiment 1, we found that Chinese-speaking participants performed better at recalling previously memorized words while sitting on a hard-surface stool (the hard condition) than a cushioned one (the soft condition). In Experiment 2, participants sitting on a cushioned stool outperformed those sitting on a hard-surface stool on a Chinese riddle task, which required creative/flexible thinking, but not on an analogical reasoning task, which required both rigid and flexible thinking. The results suggest the hardness experience affects cognitive functions that are metaphorically associated with rigidity or flexibility. They support the embodiment proposition that cognitive functions and representations can be grounded in bodily states via metaphorical associations. PMID:27672373

DInSAR time series generation within a cloud computing environment: from ERS to Sentinel-1 scenario

Science.gov (United States)

Casu, Francesco; Elefante, Stefano; Imperatore, Pasquale; Lanari, Riccardo; Manunta, Michele; Zinno, Ivana; Mathot, Emmanuel; Brito, Fabrice; Farres, Jordi; Lengert, Wolfgang

2013-04-01

One of the techniques that will strongly benefit from the advent of the Sentinel-1 system is Differential SAR Interferometry (DInSAR), which has successfully demonstrated to be an effective tool to detect and monitor ground displacements with centimetre accuracy. The geoscience communities (volcanology, seismicity, …), as well as those related to hazard monitoring and risk mitigation, make extensively use of the DInSAR technique and they will take advantage from the huge amount of SAR data acquired by Sentinel-1. Indeed, such an information will successfully permit the generation of Earth's surface displacement maps and time series both over large areas and long time span. However, the issue of managing, processing and analysing the large Sentinel data stream is envisaged by the scientific community to be a major bottleneck, particularly during crisis phases. The emerging need of creating a common ecosystem in which data, results and processing tools are shared, is envisaged to be a successful way to address such a problem and to contribute to the information and knowledge spreading. The Supersites initiative as well as the ESA SuperSites Exploitation Platform (SSEP) and the ESA Cloud Computing Operational Pilot (CIOP) projects provide effective answers to this need and they are pushing towards the development of such an ecosystem. It is clear that all the current and existent tools for querying, processing and analysing SAR data are required to be not only updated for managing the large data stream of Sentinel-1 satellite, but also reorganized for quickly replying to the simultaneous and highly demanding user requests, mainly during emergency situations. This translates into the automatic and unsupervised processing of large amount of data as well as the availability of scalable, widely accessible and high performance computing capabilities. The cloud computing environment permits to achieve all of these objectives, particularly in case of spike and peak

75 FR 32341 - Import Administration IA ACCESS Pilot Program

Science.gov (United States)

2010-06-08

... submitted electronically need not also be submitted in hard copy. Persons wishing to submit written comments in hard copy should file one signed original and two copies of each set of comments to the address... . Any questions concerning file formatting, document conversion, access on the Internet, or other...

Dinámica no lineal en la motivación en el trabajo: propuesta de un modelo y resultados preliminares

OpenAIRE

Navarro Cid, José; Quijano de Arana, Santiago D. de

2003-01-01

Muchos especialistas estarían de acuerdo en que la motivación en el trabajo debe entenderse como un proceso dinámico. Sin embargo, son pocas las investigaciones que se han interesado por la descripción y explicación de dicha dinámica motivacional. Este artículo propone un modelo complejo de motivación en el trabajo que integra tres variables clásicas en la literatura: motivos, autoeficacia e instrumentalidad. El modelo incorpora los cambios que se producen en la motivación a lo largo del tiem...

A Reusable Software Copy Protection Using Hash Result and Asymetrical Encryption

Directory of Open Access Journals (Sweden)

Aswin Wibisurya

2014-12-01

Full Text Available Desktop application is one of the most popular types of application being used in computer due to the one time install simplicity and the quick accessibility from the moment the computer being turned on. Limitation of the copy and usage of desktop applications has long been an important issue to application providers. For security concerns, software copy protection is usually integrated with the application. However, developers seek to reuse the copy protection component of the software. This paper proposes an approach of reusable software copy protection which consists of a certificate validator on the client computer and a certificate generator on the server. The certificate validator integrity is protected using hashing result while all communications are encrypted using asymmetrical encryption to ensure the security of this approach.

How bio-questionable are the different recombinant human erythropoietin copy products in Thailand?

Science.gov (United States)

Halim, Liem Andhyk; Brinks, Vera; Jiskoot, Wim; Romeijn, Stefan; Praditpornsilpa, Kearkiat; Assawamakin, Anunchai; Schellekens, Huub

2014-05-01

The high prevalence of pure red cell aplasia in Thailand has been associated with the sharp increase in number of recombinant human erythropoietin (rhEPO) copy products, based on a classical generic regulatory pathway, which have entered the market. This study aims to assess the quality of rhEPO copy products being used in Thailand. Twelve rhEPO copy products were purchased from pharmacies in Thailand, shipped under controlled cold chain conditions to the Netherlands and characterized using (1) high performance size-exclusion chromatography, (2) asymmetrical flow field-flow fractionation, (3) sodium dodecyl sulfate polyacrylamide gel electrophoresis in combination with (4) Western blotting and additionally tested for (5) host cell protein impurities as well as (6) endotoxin contamination. Some of the tested rhEPO copy products showed high aggregate levels and contained a substantial amount of protein fragments. Also, one of rhEPO copy products had a high endotoxin level, exceeding the FDA limit. Our observations show that some of the tested copy products on the Thai market differ significantly from the originator rhEPO product, Epogen®. This comparison study supports a link between the quality attributes of copy rhEPO products and their immunogenicity.

Imitation, Inspiration, and Creation: Cognitive Process of Creative Drawing by Copying Others' Artworks.

Science.gov (United States)

Okada, Takeshi; Ishibashi, Kentaro

2017-09-01

To investigate the cognitive processes underlying creative inspiration, we tested the extent to which viewing or copying prior examples impacted creative output in art. In Experiment 1, undergraduates made drawings under three conditions: (a) copying an artist's drawing, then producing an original drawing; (b) producing an original drawing without having seen another's work; and (c) copying another artist's work, then reproducing that artist's style independently. We discovered that through copying unfamiliar abstract drawings, participants were able to produce creative drawings qualitatively different from the model drawings. Process analyses suggested that participants' cognitive constraints became relaxed, and new perspectives were formed from copying another's artwork. Experiment 2 showed that exposure to styles of artwork considered unfamiliar facilitated creativity in drawing, while styles considered familiar did not do so. Experiment 3 showed that both copying and thoroughly viewing artwork executed using an unfamiliar style facilitated creativity in drawing, whereas merely thinking about alternative styles of artistic representation did not do so. These experiments revealed that deep encounters with unfamiliar artworks-whether through copying or prolonged observation-change people's cognitive representations of the act of drawing to produce novel artwork. Copyright © 2016 Cognitive Science Society, Inc.

Late Print Culture’s Social Media Revolution: Authorship, Collaboration and Copy Machines

Directory of Open Access Journals (Sweden)

Kate Eichhorn

2013-05-01

Full Text Available This article examines the impact of copy machines on late twentieth-century print cultures. Specifically, this article makes a case for “dry copying,” the method of print reproduction perfected by Xerox in the late 1950s, as a unique medium rather than a weak imitation of other printing methods. Following the claim that the widespread availability of copy machines in the late twentieth century represented the arrival of a new medium, this article further examines how understandings of authorship, established with print culture, came undone in the era of the copy machine. Finally, this paper makes a case for understanding copy machines as a form of “social media” that opened up opportunities for writers, readers and publishers to create, share, exchange and comment on texts and images in communities and networks of their own making in the decades preceding the development of the web.

Procedures for the selection of stopping power ratios for electron beams: Comparison of IAEA TRS procedures and of DIN procedures with Monte Carlo results

International Nuclear Information System (INIS)

Roos, M.; Christ, G.

2000-01-01

In the International Code of Practice IAEA TRS-381 the stopping power ratios water/air are selected according to the half-value depth and the depth of measurement. In the German Standard DIN 6800-2 a different procedure is recommended, which, in addition, takes the practical electron range into account; the stopping power data for monoenergetic beams from IAEA TRS-381 are used. Both procedures are compared with recent Monte Carlo calculations carried out for various beams of clinical accelerators. It is found that the DIN procedure shows a slightly better agreement. In addition, the stopping power ratios in IAEA TRS-381 are compared with those in DIN 6800-2 for the reference conditions of the beams from the PTB linac; the maximum deviation is not larger than 0.6%. (author)

20 CFR 404.707 - Original records or copies as evidence.

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Original records or copies as evidence. 404... DISABILITY INSURANCE (1950- ) Evidence General § 404.707 Original records or copies as evidence. (a) General... original document or record. These original records or documents will be returned to you after we have...

Dinámica de la identidad, acción y contexto

Directory of Open Access Journals (Sweden)

Anne Marie Costalat-Founeau

2007-06-01

Full Text Available La identidad social no puede ser considerada más como una imagen fijada y estática que determina las representaciones individuales y/o colectivas. Se inserta, más bien, dentro de una dinámica de representaciones que está marcada por fases biográficas y sociales. Esta impresión social está en parte construida por la experiencia personal impresa en los recuerdos, y transfiere una realidad experiencial a la identidad. La acción participa en esta concretización y también la refuerza: es así que el carácter normativo de la acción parece reforzar su propia manifestación y, por lo tanto, su efecto. Esos efectos tienen un poder central en la dinámica de la identidad. La acción se ubica en el centro de la subjetividad, pues pone en relación las aspiraciones, las representaciones y también los valores y el sentimiento de capacidad: la acción favorece una relación estrecha entre los factores afectivos y cognitivos. Esos factores actúan en conjunto elaborando regulaciones dinámicas y organizando fases de identidad más o menos conflictivas. Se presentan los efectos de la acción sobre la subjetividad.---Social identity should not be considered anymore as a fixed and static image that defines individual or collective representations. It is embedded within a representational dynamic where biographical and social phases left their marks. This social imprint is partly made by the experience ingrained in the remembrance that gives all its experiential reality to identity. Action participates and reinforces this concreteness. It seems that the prescriptive nature of action reinforces its presence and therefore its effects. More precisely, these effects, which are inherent to action, possess a central power in the identity dynamic. Action is at the heart of subjectivity in the sense that it connects aspirations, representations, as well as the values of the individual and the sense of his own capacity. It involves the tight interweaving of

48 CFR 752.7005 - Submission requirements for development experience documents.

Science.gov (United States)

2010-10-01

... (referenced in paragraph (a)(1) of this clause) in electronic format and hard copy (one copy) to U.S. Agency... final equivalent of the hard copy submitted. (iv) Acceptable software formats for electronic documents... paragraph (b)(1)(i) of this clause. (2) Format. (i) Descriptive information is required for all Contractor...

78 FR 6330 - Clinical Laboratory Improvement Advisory Committee (CLIAC)

Science.gov (United States)

2013-01-30

... Committee for their consideration and public distribution. Written comments, one hard copy with original... format (PDF) on the Internet instead of by printed copy. Refer to the CLIAC Web site on the day of the... and then emailed to the portable device. An Internet connection, power source and limited hard copies...

75 FR 62169 - Bureau of Educational and Cultural Affairs (ECA) Request for Grant Proposals: Study of the United...

Science.gov (United States)

2010-10-07

... Solicitation Package for complete budget guidelines and formatting instructions. The POGI document includes a.../USS-11-10. Methods of Submission: Applications may be submitted in one of two ways: (1) In hard-copy... hard copy original and an electronic copy of the following reports: (1.) A final program and financial...

Microbiological quality of soft, semi-hard and hard cheeses during the shelf-life

Directory of Open Access Journals (Sweden)

Josip Vrdoljak

2016-03-01

Full Text Available Cheeses as ready-to-eat food should be considered as a potential source of foodborne pathogens, primarily Listeria monocytogenes. The aim of present study was to determine the microbiological quality of soft, semi-hard and hard cheeses during the shelf-life, with particular reference to L. monocytogenes. Five types of cheeses were sampled at different timepoints during the cold storage and analyzed for presence of Salmonella and L. monocytogenes, as well as lactic acid bacteria, Escherichia coli, coagulase-positive staphylococci, yeasts, molds, sulfite-reducing clostridia and L. monocytogenes counts. Water activity, pH and NaCl content were monitored in order to evaluate the possibility of L. monocytogenes growth. Challenge test for L. monocytogenes was performed in soft whey cheese, to determine the growth potential of pathogen during the shelf-life of product. All analyzed cheeses were compliant with microbiological criteria during the shelf-life. In soft cheeses, lactic acid bacteria increased in the course of the shelf-life period (1.2-2.6 log increase, while in semi-hard and hard cheeses it decreased (1.6 and 5.2 log decrease, respectively. Soft cheeses support the growth of L. monocytogenes according to determined pH values (5.8-6.5, water activity (0.99-0.94, and NaCl content (0.3-1.2%. Challenge test showed that L. monocytogenes growth potential in selected soft cheese was 0.43 log10 cfu/g during 8 days at 4°C. Water activity in semi-hard and hard cheeses was a limiting factor for Listeria growth during the shelf-life. Soft, semi-hard and hard cheeses were microbiologically stable during their defined shelf-life. Good manufacturing and hygienic practices must be strictly followed in the production of soft cheeses as Listeria-supporting food and be focused on preventing (recontamination.

Analytical Modeling of Hard-Coating Cantilever Composite Plate considering the Material Nonlinearity of Hard Coating

Directory of Open Access Journals (Sweden)

Wei Sun

2015-01-01

Full Text Available Due to the material nonlinearity of hard coating, the coated structure produces the nonlinear dynamical behaviors of variable stiffness and damping, which make the modeling of hard-coating composite structure become a challenging task. In this study, the polynomial was adopted to characterize this material nonlinearity and an analytical modeling method was developed for the hard-coating composite plate. Firstly, to relate the hard-coating material parameters obtained by test and the analytical model, the expression of equivalent strain of composite plate was derived. Then, the analytical model of hard-coating composite plate was created by energy method considering the material nonlinearity of hard coating. Next, using the Newton-Raphson method to solve the vibration response and resonant frequencies of composite plate and a specific calculation procedure was also proposed. Finally, a cantilever plate coated with MgO + Al2O3 hard coating was chosen as study case; the vibration response and resonant frequencies of composite plate were calculated using the proposed method. The calculation results were compared with the experiment and general linear calculation, and the correctness of the created model was verified. The study shows the proposed method can still maintain an acceptable precision when the material nonlinearity of hard coating is stronger.

1 CFR 15.4 - Reproduction and certification of copies of acts and documents.

Science.gov (United States)

2010-01-01

... 1 General Provisions 1 2010-01-01 2010-01-01 false Reproduction and certification of copies of... Reproduction and certification of copies of acts and documents. The Director of the Federal Register shall furnish to requesting agencies, at cost, reproductions or certified copies of original acts and documents...

Decreases in average bacterial community rRNA operon copy number during succession.

Science.gov (United States)

Nemergut, Diana R; Knelman, Joseph E; Ferrenberg, Scott; Bilinski, Teresa; Melbourne, Brett; Jiang, Lin; Violle, Cyrille; Darcy, John L; Prest, Tiffany; Schmidt, Steven K; Townsend, Alan R

2016-05-01

Trait-based studies can help clarify the mechanisms driving patterns of microbial community assembly and coexistence. Here, we use a trait-based approach to explore the importance of rRNA operon copy number in microbial succession, building on prior evidence that organisms with higher copy numbers respond more rapidly to nutrient inputs. We set flasks of heterotrophic media into the environment and examined bacterial community assembly at seven time points. Communities were arrayed along a geographic gradient to introduce stochasticity via dispersal processes and were analyzed using 16 S rRNA gene pyrosequencing, and rRNA operon copy number was modeled using ancestral trait reconstruction. We found that taxonomic composition was similar between communities at the beginning of the experiment and then diverged through time; as well, phylogenetic clustering within communities decreased over time. The average rRNA operon copy number decreased over the experiment, and variance in rRNA operon copy number was lowest both early and late in succession. We then analyzed bacterial community data from other soil and sediment primary and secondary successional sequences from three markedly different ecosystem types. Our results demonstrate that decreases in average copy number are a consistent feature of communities across various drivers of ecological succession. Importantly, our work supports the scaling of the copy number trait over multiple levels of biological organization, ranging from cells to populations and communities, with implications for both microbial ecology and evolution.

From Copy-and-Paste to Trace-and-Learn

DEFF Research Database (Denmark)

Klitgård, Ida

2009-01-01

of them even use the term ‹copy-and-paste› to illustrate this, suggesting that their perception is closely linked to their use of the internet. This generally one-dimensional perception calls for immediate repair work in the teaching of English academic writing in International Study Programmes......This paper presents an investigation of both Danish and international second-semester BA-students' perceptions of the problem of plagiarism. Surprisingly, the investigation proves that the students unanimously perceive plagiarism as directly copying other people's texts or entire works. Some...

Dinámica del ciclo del nitrógeno y fósforo en suelos

Directory of Open Access Journals (Sweden)

Fabio Ancízar Aristizábal Gutiérrez

2012-01-01

Full Text Available Título en ingles: Nitrogen and phosphorus cycles dynamics in Soils Resumen: Los ciclos biogeoquímicos del fósforo (P y del nitrógeno (N son sistemas dinámicos que suceden a través de la biosfera, de cuyos mecanismos de transformación depende la disponibilidad de estos elementos para diferentes formas de vida.  Se acepta que la diversidad y actividad de las poblaciones microbianas posee un papel crucial en la dinámica de los nutrientes y por tanto el desafío está en comprender, como responden a las condiciones ambientales. La actividad microbiana en los suelos depende tanto de la condición del recurso y como de sus propiedades químicas, físicas y biológicas.  En este documento se describen conceptos que se han empleado para entender la dinámica del nitrógeno y el fósforo, con el propósito de discutir cómo las características de las diferentes fracciones orgánicas y minerales seleccionan el potencial biológico encargado del recambio de dichos elementos,  panorama que actualmente se aborda a través de técnicas independientes del cultivo para estudiar las poblaciones microbianas in situ.  Palabras clave: dinámica de N y P; disponibilidad de nutrientes en suelo; fracciones orgánicas e inorgánicas y actividad microbiana. Abstract: Biogeochemical cycle’s phosphorus (P and nitrogen (N are dynamic systems taking place through the biosphere, whose mechanisms of transformation depends on the availability of these elements for different forms of life.  It is accepted that the diversity and activity of microbial populations plays a crucial role in nutrient dynamics and therefore the challenge is to understand how they respond to environmental conditions. Microbial activity in soils depends on both the resource condition and its chemical, physical and biological properties. Concepts described herein have been used to understand the nitrogen and phosphorus dynamics, with the aim to discuss how the characteristics of the

Accurate measurement of gene copy number for human alpha-defensin DEFA1A3.

Science.gov (United States)

Khan, Fayeza F; Carpenter, Danielle; Mitchell, Laura; Mansouri, Omniah; Black, Holly A; Tyson, Jess; Armour, John A L

2013-10-20

Multi-allelic copy number variants include examples of extensive variation between individuals in the copy number of important genes, most notably genes involved in immune function. The definition of this variation, and analysis of its impact on function, has been hampered by the technical difficulty of large-scale but accurate typing of genomic copy number. The copy-variable alpha-defensin locus DEFA1A3 on human chromosome 8 commonly varies between 4 and 10 copies per diploid genome, and presents considerable challenges for accurate high-throughput typing. In this study, we developed two paralogue ratio tests and three allelic ratio measurements that, in combination, provide an accurate and scalable method for measurement of DEFA1A3 gene number. We combined information from different measurements in a maximum-likelihood framework which suggests that most samples can be assigned to an integer copy number with high confidence, and applied it to typing 589 unrelated European DNA samples. Typing the members of three-generation pedigrees provided further reassurance that correct integer copy numbers had been assigned. Our results have allowed us to discover that the SNP rs4300027 is strongly associated with DEFA1A3 gene copy number in European samples. We have developed an accurate and robust method for measurement of DEFA1A3 copy number. Interrogation of rs4300027 and associated SNPs in Genome-Wide Association Study SNP data provides no evidence that alpha-defensin copy number is a strong risk factor for phenotypes such as Crohn's disease, type I diabetes, HIV progression and multiple sclerosis.

Mate-choice copying, social information processing, and the roles of oxytocin.

Science.gov (United States)

Kavaliers, Martin; Matta, Richard; Choleris, Elena

2017-01-01

Social and sexual behaviors, including that of mate choice, are dependent on social information. Mate choice can be modified by prior and ongoing social factors and experience. The mate choice decisions of one individual can be influenced by either the actual or potential mate choice of another female or male. Such non-independent mate choice, where individuals gain social information and socially learn about and recognizes potential mates by observing the choices of another female or male, has been termed "mate-choice copying". Here we first briefly review how, why, and under what circumstances individuals engage in mate-choice copying. Secondly, we review the neurobiological mechanisms underlying mate-choice copying. In particular, we consider the roles of the nonapeptide, oxytocin, in the processing of social information and the expression of mate-choice copying. Copyright © 2016 Elsevier Ltd. All rights reserved.

Chemical hardness and density functional theory

Indian Academy of Sciences (India)

Unknown

RALPH G PEARSON. Chemistry Department, University of California, Santa Barbara, CA 93106, USA. Abstract. The concept of chemical hardness is reviewed from a personal point of view. Keywords. Hardness; softness; hard & soft acids bases (HSAB); principle of maximum hardness. (PMH) density functional theory (DFT) ...

Hardness variability in commercial technologies

International Nuclear Information System (INIS)

Shaneyfelt, M.R.; Winokur, P.S.; Meisenheimer, T.L.; Sexton, F.W.; Roeske, S.B.; Knoll, M.G.

1994-01-01

The radiation hardness of commercial Floating Gate 256K E 2 PROMs from a single diffusion lot was observed to vary between 5 to 25 krad(Si) when irradiated at a low dose rate of 64 mrad(Si)/s. Additional variations in E 2 PROM hardness were found to depend on bias condition and failure mode (i.e., inability to read or write the memory), as well as the foundry at which the part was manufactured. This variability is related to system requirements, and it is shown that hardness level and variability affect the allowable mode of operation for E 2 PROMs in space applications. The radiation hardness of commercial 1-Mbit CMOS SRAMs from Micron, Hitachi, and Sony irradiated at 147 rad(Si)/s was approximately 12, 13, and 19 krad(Si), respectively. These failure levels appear to be related to increases in leakage current during irradiation. Hardness of SRAMs from each manufacturer varied by less than 20%, but differences between manufacturers are significant. The Qualified Manufacturer's List approach to radiation hardness assurance is suggested as a way to reduce variability and to improve the hardness level of commercial technologies

18 CFR 45.7 - Form of application; number of copies.

Science.gov (United States)

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Form of application; number of copies. 45.7 Section 45.7 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... in accordance with § 131.60 of this chapter. Each copy shall bear the date and signature that appear...

Modeled long-term changes of DIN:DIP ratio in the Changjiang River in relation to Chl-α and DO concentrations in adjacent estuary

Science.gov (United States)

Wang, Jianing; Yan, Weijin; Chen, Nengwang; Li, Xinyan; Liu, Lusan

2015-12-01

In the past four decades (1970-2013), nitrogen and phosphorous inputs to the Changjiang River basin, mainly from human activities, have increased 3-fold and 306-fold, respectively. The riverine nutrient fluxes to the estuary have also grown exponentially. Dissolved inorganic nitrogen (DIN) and dissolved inorganic phosphorous (DIP) fluxes of the Changjiang River increased by 338% and 574% during 1970-2013 period, and red tides and benthic hypoxia have been observed in the outflow region of the Changjiang River in the East China Sea (ECS). We assumed that time series changes in the DIN:DIP ratio from the Changjiang River could have a significant impact on Chlorophyll-α (Chl-α) concentration in the surface sea water and dissolved oxygen (DO) concentration in the bottom sea water of the Changjiang estuary. Our study showed that the DIN:DIP ratio from the Changjiang River increased from 76 to 384 between 1970 and 1985, and decreased from 255 to 149 between 1986 and 2013. The observed Chl-α concentration increased by 146% from 1992 to 2010 in the Changjiang estuary, and was negatively related to the DIN:DIP ratio in 1992-2010. Bottom sea water DO concentration decreased by 24.6% during 1992-2010 and a "low oxygen zone" (122°∼123°E, 32°∼33°N) was observed during summer since 1999. The anthropogenically enhanced nutrient inputs dominated river DIN and DIP fluxes and influenced Chl-α concentrations as well as bottom DO concentrations in the estuary. Scenarios emphasizing global collaboration and proactive environmental problem-solving may result in reductions in the river nutrient exports and in Chl-α and DO concentration in the Changjiang estuary by 2050.

39 CFR 3007.10 - Submission of non-public materials under seal.

Science.gov (United States)

2010-07-01

...-public materials shall submit two copies consisting, where practicable, of two paper hard copies as well... available PC application. Each page of any paper hard copy non-public materials submitted shall be clearly... submitted in a searchable electronic format, but need not be submitted in its native format. As part of its...

Does testing with feedback improve adult spelling skills relative to copying and reading?

Science.gov (United States)

Pan, Steven C; Rubin, Benjamin R; Rickard, Timothy C

2015-12-01

We examined testing's ability to enhance adult spelling acquisition, relative to copying and reading. Across 3 experiments in which testing with feedback was compared with copying, the spelling improvement after testing matched that following the same amount of time spent copying. A potent testing advantage, however, was observed for spelling words free-recalled. In the fourth experiment, a large testing advantage for both word free recall and spelling was observed, versus reading. Subjects also generally preferred testing and rated it as more effective than copying or reading. The equivalent performance of testing and copying for spelling contrasts with prior work involving children and suggests that retrieval practice may not be the only effective mechanism for spelling skill acquisition. Rather, we suggest that the critical learning event for spelling is focused study on phoneme-to-grapheme mappings for previously unlearned letter sequences. For adults with extensive spelling expertise, focused study is more automatic during both copying and testing with feedback than for individuals with beginning spelling skills. Reading, however, would not be expected to produce efficient focused study of phoneme-to-grapheme mappings, regardless of expertise level. Overall, adult spelling skill acquisition benefits both from testing and copying, and substantially less from reading. (c) 2015 APA, all rights reserved).

Using DMA for copying performance counter data to memory

Science.gov (United States)

Gara, Alan; Salapura, Valentina; Wisniewski, Robert W

2013-12-31

A device for copying performance counter data includes hardware path that connects a direct memory access (DMA) unit to a plurality of hardware performance counters and a memory device. Software prepares an injection packet for the DMA unit to perform copying, while the software can perform other tasks. In one aspect, the software that prepares the injection packet runs on a processing core other than the core that gathers the hardware performance data.

Modelo de capacidad dinámica de aprendizaje organizacional: experiencia de la biotecnológia en Cuba

Directory of Open Access Journals (Sweden)

Marle Pérez de Armas

2016-01-01

Full Text Available La experiencia y práctica internacional fundamentan el conocimiento como recurso estratégico y resultado del aprendizaje organizacional, lo que conduce a plantear la Capacidad Dinámica de Aprendizaje Organizacional vinculada con la obtención de resultados de desempeños positivos y fuente de ventajas competitivas. En este sentido, la empresa de alta tecnología (EAT del sector de la biotecnología en Cuba representa una experiencia singular lo que se vincula con el problema científico, ya que se necesita explicar, sobre bases científicas, cómo el desarrollo de la Capacidad Dinámica de Aprendizaje Organizacional contribuye a fundamentar el éxito alcanzado por empresas líderes del sector, y que a su vez posibiliten su extensión a otras de su tipo en el sector. A partir de la utilización de la metodología de estudio de caso aplicada al Centro de Inmunología Molecular como caso piloto y el juicio de expertos se obtiene como, principal resultado, un modelo conceptual que fundamenta y explica el éxito alcanzado por empresas líderes de alta tecnología del sector biotecnológico cubano desde el desarrollo de la Capacidad Dinámica de Aprendizaje Organizacional y sus tres dimensiones claves: elementos de gestión técnico-organizativos, comportamiento organizacional y actores externos.

Modelo de capacidad dinámica de aprendizaje organizacional: experiencia de la biotecnología en Cuba

Directory of Open Access Journals (Sweden)

Marle Pérez De Armas

2016-06-01

Full Text Available La experiencia y práctica internacional fundamentan el conocimiento como recurso estratégico y resultado del aprendizaje organizacional, lo que conduce a plantear la Capacidad Dinámica de Aprendizaje Organizacional vinculada con la obtención de resultados de desempeños positivos y fuente de ventajas competitivas. En este sentido, la empresa de alta tecnología (EAT del sector de la biotecnología en Cuba representa una experiencia singular lo que se vincula con el problema científico, ya que se necesita explicar, sobre bases científicas, cómo el desarrollo de la Capacidad Dinámica de Aprendizaje Organizacional contribuye a fundamentar el éxito alcanzado por empresas líderes del sector, y que a su vez posibiliten su extensión a otras de su tipo en el sector. A partir de la utilización de la metodología de estudio de caso aplicada al Centro de Inmunología Molecular como caso piloto y el juicio de expertos se obtiene como, principal resultado, un modelo conceptual que fundamenta y explica el éxito alcanzado por empresas líderes de alta tecnología del sector biotecnológico cubano desde el desarrollo de la Capacidad Dinámica de Aprendizaje Organizacional y sus tres dimensiones claves: elementos de gestión técnico-organizativos, comportamiento organizacional y actores externos.

Ensayo sobre endurecimiento de adhesivos estructurales sometidos a cargas dinámicas

Directory of Open Access Journals (Sweden)

Recuero, A.

2004-04-01

Full Text Available Carbon fibre reinforced polymers are increasingly replacing the steel reinforcing systems in the repair and strengthening of concrete structures thanks to their high strength/weight and stiffness/weight ratios, corrosion resistance, lightweight, and ease of handling and application. This paper presents a study on the behaviour of bridge concrete beams strengthened with CFRP sheets when the strengthening is made when traffic is acting so that the structure is subjected to dynamic loads while the adhesive is still fresh. No reduction in the effectiveness of the strengthening was observed in the tests.

Los polímeros reforzados con fibras de carbono se están utilizando cada vez más para el refuerzo de estructuras de hormigón, reemplazando a los sistemas tradicionales de refuerzo con acero. Esto es debido a sus altas resistencia y rigidez específicas, resistencia a la corrosión, ligereza y facilidad de manejo y puesta en obra. Este artículo presenta un estudio sobre el comportamiento de vigas de puentes reforzadas con bandas de CFRP mientras se mantiene el puente en servicio de manera que la estructura está sometida a cargas dinámicas con el adhesivo fresco. En los ensayos realizados se ha observado que las cargas dinámicas no afectan a la efectividad del refuerzo.

Şcoli şi biserici româneşti din Peninsula Balcanică 1864-1948. Documente de arhivă

Directory of Open Access Journals (Sweden)

Adina Berciu-Drăghicescu

2006-01-01

Full Text Available Articolul de faţă privind şcolile şi bisericile româneşti din Peninsula Balcanică în perioada 1918-1948 este realizat pe baza unor documente identificate în fonduri păstrate la Arhivele Diplomatice ale Ministerului Afacerilor Externe şi la Direcţia Arhivelor Naţioanle Istorice Centrale din Bucureşti. Au fost studiate şi selectate documente de cea mai mare semnificaţie în scopul prezentării evoluţiei situaţiei şcolilor şi bisericilor comunităţilor româneşti situate la sud de Dunăre începând cu anul 1864, când a fost înfiinţată prima şcoală în Târnova (Macedonia şi până în 1948 când statul român a abandonat acţiunea iniţiată de conducătorul Al. Ioan Cuza. Articolul prezintă această situaţie, foarte dramatică, a comunităţilor româneşti din Balcani pe baza documentelor de arhivă.

20 CFR 416.804 - Certified copy in lieu of original.

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Certified copy in lieu of original. 416.804... AGED, BLIND, AND DISABLED Determination of Age § 416.804 Certified copy in lieu of original. In lieu of the original of any record, except a Bible or other family record, there may be submitted as evidence...

IDEEA „DACO-ROMÂNISMULUI” LA ROMÂNII DIN TRANSILVANIA ÎN EPOCA MODERNĂ

Directory of Open Access Journals (Sweden)

Radu ROMÎNAŞU

2017-08-01

Full Text Available Îndelungata stare de fragmentarism teritorial şi de separatism politic între români a generat o criză a conştiinţelor liderilor din spaţiul românesc, tensiune din care s-a cristalizat ideea „daco-românismului”. Aceasta s-a concretizat prin iniţierea unei lupte naţionale, în special în spaţiul transilvănean, al cărei punct final a fost constituirea unei Românii întregite, rotunda şi adevărata patrie a tuturor românilor, care a reuşit să fixeze, în memoria urmaşilor, fireştile sale contururi geografice la 1 decembrie 1918.Astfel, ideea „daco-românismului” a devenit coşmarul guvernelor maghiare din perioada dualistă, neamul românesc fiind proiectat, potrivit acestei „legi nescrise” de la nivelul mentalului colectiv al elitei româneşti, ca un tot unitar, graniţele artificiale reuşind să despartă persoane, dar nu şi simţămintele sufleteşti fireşti.Esenţială şi necesară pentru transformarea vechii idei a „daco-românismului” în principiu politic-cultural a fost sinteza cultural-naţională a românilor din monarhia austro-ungară şi a celor din Vechiul Regat, care a pregătit conştiinţele pentru actul istoric de la 1 decembrie 1918.„Daco-românismul” a avut marele merit de a fi chemat la reflexie angajată în jurul unor idei majore, precum: „istorie”, „naţiune”, „neam”, „confesiune”, „conştiinţă naţională”, „limbă”, „cultură”, „politică”, ce-şi resemnifică mereu, pentru fiecare dintre vremuri în parte, conţinuturile.THE IDEA OF “DACO-ROMANIANISM” AT THE ROMANIANS LIVING IN TRANSYLVANIA DURING THE MODERN AGEThe long state of territorial fragmentation and political separatism among the Romanians generated a crisis of the leaders’ conscience on the Romanian territory, tension that crystallized the idea of “Daco-Romanianism”. This resulted in the initiation of some national struggles, especially in the Transylvanian area, whose end

Influencia del modelo elástico en la dinámica de estructuras articuladas

OpenAIRE

Muñoz, M.; López-Hernández, E.

1997-01-01

Se estudia la influencia en la dinámica de una estructura articulada de barras de madera, de la aproximación a las propiedades tensión-deformación del material. Se ha adoptado un método de cálculo por diferencias finitas en el dominio del tiempo, con un modelo de masas concentradas en los nodos.

La nueva dinámica de acumulación resumen capitalista y los problemas sociales y regionales

Directory of Open Access Journals (Sweden)

Benjamín Afanador Vargas

2004-07-01

Full Text Available El objetivo del presente trabajo es mostrar los cambios en las estrategias productivas y competitivasa que se ven enfrentadas las firmas en un mercado cada vez más integrado y competitivo en elámbito internacional. En este contexto el capital, como expresión universal de poder y dominaciónpolítica y económica, establece dinámicas entre Estados, regiones y grupos de individuos. Estascomplejas relaciones en que unos y otros actores se mueven, jugando las estrategias impuestaspor el gran capital, va develando roles y actores ganadores y perdedores en que las opcionesmenos favorables las tienen las empresas y las regiones que tienen mayores dificultades parainterpretar las nuevas reglas del juego o tienen menores condiciones y habilidades, naturales oadquiridas, para entrar en la dinámica del mercado global.

Elementos de escala en la evaluación dinámica de macizos rocosos (propuesta metodológica

Directory of Open Access Journals (Sweden)

Álvaro Orlando Pedroza Rojas, Mario Camilo Torres Suárez

2011-05-01

Full Text Available Distintas  situaciones  conforman  la  realidad  del ejercicio  geotécnico,   entre  otras:  la  relativa superficialidad de la profundidad de emplazamiento de las obras civiles, un medio dinámicamente activo sometido a cargas  igualmente dinámicas y el hecho frecuente de proyectar y diseñar las obras geotécnicas con  base  en  respuestas  geomecánicas  de muestras de  rocas  definidas  como  representativas  de  los macizos  rocosos  de  emplazamiento,   con  lasdificultades  que  conlleva  asignar  al medio  natural propiedades de resistencia y deformabilidad a partirde  las  pruebas  en  laboratorio  sobre  muestras representativas.  El  artículo  presenta  algunos lineamientos  y  elementos  de  escala  sugeridos  para ser  considerados  en  los  estudios de  caracterización de macizos  rocosos, con énfasis dinámico. A partir de los desarrollos de Brillouin (1946 y Torres (2005,los  autores  proponen  un  proceso metodológico orientado a establecer un factor de escala entre dos niveles  de  estudio:  tamaño  de muestra  y macizorocoso.

Copy-writing Post-Soviet Russia. Viktor Pelevin's work in Postcolonial Terms

NARCIS (Netherlands)

Noordenbos, Boris; Brouwer, S

2008-01-01

The copywriters and creatives in Viktor Pelevin's novel Generation "II" (1999) both 'copy' and 'write' Russian identity. Through advertising texts, video scripts, and written scenario's for Russia's stage-set democracy, the commercial elite makes Russia into a superficial and virtual copy of 'the

Statistical Methods for the detection of answer copying on achievement tests

NARCIS (Netherlands)

Sotaridona, Leonardo

2003-01-01

This thesis contains a collection of studies where statistical methods for the detection of answer copying on achievement tests in multiple-choice format are proposed and investigated. Although all methods are suited to detect answer copying, each method is designed to address specific

15 CFR 700.13 - Acceptance and rejection of rated orders.

Science.gov (United States)

2010-01-01

... order and transmit the acceptance or rejection in writing (hard copy), or in electronic format, within... rejection, pursuant to paragraphs (b) and (c) of this section, in writing (hard copy) or electronic format...

Determination of organic fluorine in aqueous samples with neutron activation analysis in comparison with the DIN method

Energy Technology Data Exchange (ETDEWEB)

Rollinger, D. [Institut fuer Kernchemie, Universitaet Mainz, Fritz-Strassmann-Weg 2, D-55099 Mainz (Germany); Kratz, K.L. [Institut fuer Kernchemie, Universitaet Mainz, Fritz-Strassmann-Weg 2, D-55099 Mainz (Germany)

1996-04-01

Neutron activation analysis (NAA) has been used as detection technique for adsorbable organic fluorine in aqueous samples. The results have been compared with the standardized DIN method which uses a fluoride-ion-selective electrode (ISE). (orig.). With 3 tabs.

International Journal of Community Research: Journal Sponsorship

African Journals Online (AJOL)

Sources of Support. Article publication charges, Sale of hard copies and subscriptions. * All accepted articles for publication in IJCR attracts an article processing fee of $85 or its Naira equivalent. Hard Copies Produced at the end of the Publication Year shall be sent at no cost to the principal authors. However, extra copies ...

CopyNumber450kCancer: baseline correction for accurate copy number calling from the 450k methylation array.

Science.gov (United States)

Marzouka, Nour-Al-Dain; Nordlund, Jessica; Bäcklin, Christofer L; Lönnerholm, Gudmar; Syvänen, Ann-Christine; Carlsson Almlöf, Jonas

2016-04-01

The Illumina Infinium HumanMethylation450 BeadChip (450k) is widely used for the evaluation of DNA methylation levels in large-scale datasets, particularly in cancer. The 450k design allows copy number variant (CNV) calling using existing bioinformatics tools. However, in cancer samples, numerous large-scale aberrations cause shifting in the probe intensities and thereby may result in erroneous CNV calling. Therefore, a baseline correction process is needed. We suggest the maximum peak of probe segment density to correct the shift in the intensities in cancer samples. CopyNumber450kCancer is implemented as an R package. The package with examples can be downloaded at http://cran.r-project.org nour.marzouka@medsci.uu.se Supplementary data are available at Bioinformatics online. © The Author 2015. Published by Oxford University Press.

Human mate-choice copying is domain-general social learning.

Science.gov (United States)

Street, Sally E; Morgan, Thomas J H; Thornton, Alex; Brown, Gillian R; Laland, Kevin N; Cross, Catharine P

2018-01-29

Women appear to copy other women's preferences for men's faces. This 'mate-choice copying' is often taken as evidence of psychological adaptations for processing social information related to mate choice, for which facial information is assumed to be particularly salient. No experiment, however, has directly investigated whether women preferentially copy each other's face preferences more than other preferences. Further, because prior experimental studies used artificial social information, the effect of real social information on attractiveness preferences is unknown. We collected attractiveness ratings of pictures of men's faces, men's hands, and abstract art given by heterosexual women, before and after they saw genuine social information gathered in real time from their peers. Ratings of faces were influenced by social information, but no more or less than were images of hands and abstract art. Our results suggest that evidence for domain-specific social learning mechanisms in humans is weaker than previously suggested.

47 CFR 1.359 - Proof of official record; authentication of copy.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 1 2010-10-01 2010-10-01 false Proof of official record; authentication of copy. 1.359 Section 1.359 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL PRACTICE AND PROCEDURE Hearing Proceedings Evidence § 1.359 Proof of official record; authentication of copy. An official...

47 CFR 1.735 - Copies; service; separate filings against multiple defendants.

Science.gov (United States)

2010-10-01

... overnight delivery service such as, or comparable to, the US Postal Service Express Mail, United Parcel... 47 Telecommunication 1 2010-10-01 2010-10-01 false Copies; service; separate filings against... Complaints § 1.735 Copies; service; separate filings against multiple defendants. (a) Complaints may...

Influencia del medio ambiente en los materiales de construcción III. Dinámica salina

Directory of Open Access Journals (Sweden)

Fernández Paris, José Manuel

1978-06-01

Full Text Available Las sales y la humedad son los dos factores que condicionan las alteraciones de los materiales de construcción. Los citados materiales, bien de por sí —piedras y ladrillos—, bien una vez endurecidos —morteros y hormigones—, están estructurados por partículas sólidas granulares, separadas por un sistema poroso, que constituye el medio -dinámico para el transporte de las disoluciones salinas procedentes del medio ambiente. La motilidad de las sales a través de la red de poros es función de tres variables físicoclimáticas: temperatura, humedad y condiciones de aireación. La dinámica salina se efectúa mediante procesos de difusión, unas veces de naturaleza química: difusión iónica, otras de naturaleza física: difusión capilar.

Generalized hedgehog ansatz and Gribov copies in regions with nontrivial topologies

Science.gov (United States)

Canfora, Fabrizio; Salgado-Rebolledo, Patricio

2013-02-01

In this paper the arising of Gribov copies both in Landau and Coulomb gauges in regions with nontrivial topologies but flat metric, (such as closed tubes S1×D2, or R×T2) will be analyzed. Using a novel generalization of the hedgehog ansatz beyond spherical symmetry, analytic examples of Gribov copies of the vacuum will be constructed. Using such ansatz, we will also construct the elliptic Gribov pendulum. The requirement of absence of Gribov copies of the vacuum satisfying the strong boundary conditions implies geometrical constraints on the shapes and sizes of the regions with nontrivial topologies.

[Application of rational ant colony optimization to improve the reproducibility degree of laser three-dimensional copy].

Science.gov (United States)

Cui, Xiao-Yan; Huo, Zhong-Gang; Xin, Zhong-Hua; Tian, Xiao; Zhang, Xiao-Dong

2013-07-01

Three-dimensional (3D) copying of artificial ears and pistol printing are pushing laser three-dimensional copying technique to a new page. Laser three-dimensional scanning is a fresh field in laser application, and plays an irreplaceable part in three-dimensional copying. Its accuracy is the highest among all present copying techniques. Reproducibility degree marks the agreement of copied object with the original object on geometry, being the most important index property in laser three-dimensional copying technique. In the present paper, the error of laser three-dimensional copying was analyzed. The conclusion is that the data processing to the point cloud of laser scanning is the key technique to reduce the error and increase the reproducibility degree. The main innovation of this paper is as follows. On the basis of traditional ant colony optimization, rational ant colony optimization algorithm proposed by the author was applied to the laser three-dimensional copying as a new algorithm, and was put into practice. Compared with customary algorithm, rational ant colony optimization algorithm shows distinct advantages in data processing of laser three-dimensional copying, reducing the error and increasing the reproducibility degree of the copy.

Curvature tensor copies in affine geometry

International Nuclear Information System (INIS)

Srivastava, P.P.

1981-01-01

The sets of space-time and spin-connections which give rise to the same curvature tensor are constructed. The corresponding geometries are compared. Results are illustrated by an explicit calculation and comment on the copies in Einstein-Cartan and Weyl-Cartan geometries. (Author) [pt

La dinámica del subdesarrollo y su relación con el deterioro ambiental

Directory of Open Access Journals (Sweden)

Carlos Dionisio Pérez-Blanco

2012-01-01

Full Text Available ¿Son los países desarrollados los culpables del deterioro ambiental?, y por tanto, ¿tienen los países subdesarrollados derecho a contaminar más? En este artículo se rebate esta tesis para mostrar que una dinámica de crecimiento que conduce al desarrollo de un territorio de renta baja debe ser por necesidad sostenible, si este país no desea liquidar sus posibilidades de desarrollo. Partiendo de las principales aportaciones teóricas de la economía del desarrollo, el artículo defiende la reciprocidad entre desarrollo y calidad ambiental. Se señala la dificultad que tienen los países subdesarrollados para abandonar un equilibrio de bajo nivel, y lo que esto implica en su riqueza (en concreto su capital ambiental, que es la que en última instancia determina su capacidad de generar renta en el futuro. Se requiere por tanto una comprensión profunda de la dinámica del subdesarrollo para frenar el deterioro ambiental.

Study of tempering process of a DIN 1.2714 steel modified by niobium

International Nuclear Information System (INIS)

Oliveira, Carlos A.S. de.

1985-01-01

The carbides precipitaton in a DIN 1.2714 steel modified by niobium are studied. Three austenitizing temperatures (1200, 960 and 860 0 C) after homogenization at 1200 0 C are used; and the precipitation behavior of the carbides on tempering at 600 0 C with respect to time is studied. These precipitates were characterized through the X-ray fluorescence and diffraction and by carbon extraction replica techniques for transmission electron microscope. (M.J.C.) [pt

1 CFR 19.3 - Routing and certification of originals and copies.

Science.gov (United States)

2010-01-01

... 1 General Provisions 1 2010-01-01 2010-01-01 false Routing and certification of originals and... certification of originals and copies. (a) If the order or proclamation is signed by the President, the original...: “Certified to be a true copy of the original.” ...

Inferring Variation in Copy Number Using High Throughput Sequencing Data in R.

Science.gov (United States)

Knaus, Brian J; Grünwald, Niklaus J

2018-01-01

Inference of copy number variation presents a technical challenge because variant callers typically require the copy number of a genome or genomic region to be known a priori . Here we present a method to infer copy number that uses variant call format (VCF) data as input and is implemented in the R package vcfR . This method is based on the relative frequency of each allele (in both genic and non-genic regions) sequenced at heterozygous positions throughout a genome. These heterozygous positions are summarized by using arbitrarily sized windows of heterozygous positions, binning the allele frequencies, and selecting the bin with the greatest abundance of positions. This provides a non-parametric summary of the frequency that alleles were sequenced at. The method is applicable to organisms that have reference genomes that consist of full chromosomes or sub-chromosomal contigs. In contrast to other software designed to detect copy number variation, our method does not rely on an assumption of base ploidy, but instead infers it. We validated these approaches with the model system of Saccharomyces cerevisiae and applied it to the oomycete Phytophthora infestans , both known to vary in copy number. This functionality has been incorporated into the current release of the R package vcfR to provide modular and flexible methods to investigate copy number variation in genomic projects.

Improved Ordinary Measure and Image Entropy Theory based intelligent Copy Detection Method

Directory of Open Access Journals (Sweden)

Dengpan Ye

2011-10-01

Full Text Available Nowadays, more and more multimedia websites appear in social network. It brings some security problems, such as privacy, piracy, disclosure of sensitive contents and so on. Aiming at copyright protection, the copy detection technology of multimedia contents becomes a hot topic. In our previous work, a new computer-based copyright control system used to detect the media has been proposed. Based on this system, this paper proposes an improved media feature matching measure and an entropy based copy detection method. The Levenshtein Distance was used to enhance the matching degree when using for feature matching measure in copy detection. For entropy based copy detection, we make a fusion of the two features of entropy matrix of the entropy feature we extracted. Firstly,we extract the entropy matrix of the image and normalize it. Then, we make a fusion of the eigenvalue feature and the transfer matrix feature of the entropy matrix. The fused features will be used for image copy detection. The experiments show that compared to use these two kinds of features for image detection singly, using feature fusion matching method is apparent robustness and effectiveness. The fused feature has a high detection for copy images which have been received some attacks such as noise, compression, zoom, rotation and so on. Comparing with referred methods, the method proposed is more intelligent and can be achieved good performance.

Studying Hardness Meter Spring Strength to Understand Hardness Distribution on Body Surfaces.

Science.gov (United States)

Arima, Yoshitaka

2017-10-01

For developing a hardness multipoint measurement system for understanding hardness distribution on biological body surfaces, we investigated the spring strength of the contact portion main axis of a biological tissue hardness meter (product name: PEK). We measured the hardness of three-layered sheets of six types of gel sheets (90 mm × 60 mm × 6 mm) constituting the acupuncture practice pads, with PEK measurements of 1.96 N, 2.94 N, 3.92 N, 4.90 N, 5.88 N, 6.86 N, 7.84 N, 8.82 N, and 9.81 N of the main axis spring strength. We obtained measurements 10 times for the gel sheets and simultaneously measured the load using a digital scale. We measured the hardness distribution of induration embedded and breast cancer palpation models, with a main axis with 1.96 N, 4.90 N, and 9.81 N spring strengths, to create a two-dimensional Contour Fill Chart. Using 4.90 N spring strength, we could obtain measurement loads of ≤3.0 N, and the mean hardness was 5.14 mm. This was close to the median of the total measurement range 0.0-10.0 mm, making the measurement range the largest for this spring strength. We could image the induration of the induration-embedded model regardless of the spring strength. Overall, 4.90 N spring strength was best suited for imaging cancer in the breast cancer palpation model. Copyright © 2017. Published by Elsevier B.V.

Chimpanzees copy dominant and knowledgeable individuals: implications for cultural diversity.

Science.gov (United States)

Kendal, Rachel; Hopper, Lydia M; Whiten, Andrew; Brosnan, Sarah F; Lambeth, Susan P; Schapiro, Steven J; Hoppitt, Will

2015-01-01

Evolutionary theory predicts that natural selection will fashion cognitive biases to guide when, and from whom, individuals acquire social information, but the precise nature of these biases, especially in ecologically valid group contexts, remains unknown. We exposed four captive groups of chimpanzees ( Pan troglodytes ) to a novel extractive foraging device and, by fitting statistical models, isolated four simultaneously operating transmission biases. These include biases to copy (i) higher-ranking and (ii) expert individuals, and to copy others when (iii) uncertain or (iv) of low rank. High-ranking individuals were relatively un-strategic in their use of acquired knowledge, which, combined with the bias for others to observe them, may explain reports that high innovation rates (in juveniles and subordinates) do not generate a correspondingly high frequency of traditions in chimpanzees. Given the typically low rank of immigrants in chimpanzees, a 'copying dominants' bias may contribute to the observed maintenance of distinct cultural repertoires in neighboring communities despite sharing similar ecology and knowledgeable migrants. Thus, a copying dominants strategy may, as often proposed for conformist transmission, and perhaps in concert with it, restrict the accumulation of traditions within chimpanzee communities whilst maintaining cultural diversity.

The Origin of Mutants Under Selection: How Natural Selection Mimics Mutagenesis (Adaptive Mutation)

Science.gov (United States)

Maisnier-Patin, Sophie; Roth, John R.

2015-01-01

Selection detects mutants but does not cause mutations. Contrary to this dictum, Cairns and Foster plated a leaky lac mutant of Escherichia coli on lactose medium and saw revertant (Lac+) colonies accumulate with time above a nongrowing lawn. This result suggested that bacteria might mutagenize their own genome when growth is blocked. However, this conclusion is suspect in the light of recent evidence that revertant colonies are initiated by preexisting cells with multiple copies the conjugative F′lac plasmid, which carries the lac mutation. Some plated cells have multiple copies of the simple F′lac plasmid. This provides sufficient LacZ activity to support plasmid replication but not cell division. In nongrowing cells, repeated plasmid replication increases the likelihood of a reversion event. Reversion to lac+ triggers exponential cell growth leading to a stable Lac+ revertant colony. In 10% of these plated cells, the high-copy plasmid includes an internal tandem lac duplication, which provides even more LacZ activity—sufficient to support slow growth and formation of an unstable Lac+ colony. Cells with multiple copies of the F′lac plasmid have an increased mutation rate, because the plasmid encodes the error-prone (mutagenic) DNA polymerase, DinB. Without DinB, unstable and stable Lac+ revertant types form in equal numbers and both types arise with no mutagenesis. Amplification and selection are central to behavior of the Cairns–Foster system, whereas mutagenesis is a system-specific side effect or artifact caused by coamplification of dinB with lac. Study of this system has revealed several broadly applicable principles. In all populations, gene duplications are frequent stable genetic polymorphisms, common near-neutral mutant alleles can gain a positive phenotype when amplified under selection, and natural selection can operate without cell division when variability is generated by overreplication of local genome subregions. PMID:26134316

Del modelo extractivista a las dinámicas de desarrollo local en contextos de conflicto: distrito minero litoral pacífico (2008-2012)

OpenAIRE

Pardo Durán, Joan Sebastián

2016-01-01

La presente investigación tiene como objetivo principal, analizar las dinámicas de desarrollo local del distrito minero Litoral Pacífico durante el periodo 2008-2012 a partir del modelo extractivista, con el fin de demostrar que, a pesar del auge minero durante estos gobiernos, el crecimiento de la actividad y la entrada de capital a estos municipios, el desarrollo local es escaso ante las dinámicas del conflicto armado interno y el abandono estatal que ha existido por excelencia en esta zona...

Multi-centered N=2 BPS black holes: a double copy description

Energy Technology Data Exchange (ETDEWEB)

Cardoso, G.L.; Nagy, S.; Nampuri, S. [Center for Mathematical Analysis, Geometry and Dynamical Systems,Department of Mathematics, Instituto Superior Técnico, Universidade de Lisboa,Av. Rovisco Pais, Lisboa, 1049-001 (Portugal)

2017-04-07

We present the on-shell double copy dictionary for linearised N=2 supergravity coupled to an arbitrary number of vector multiplets in four dimensions. Subsequently, we use it to construct a double copy description of multi-centered BPS black hole solutions in these theories in the weak-field approximation.

Allelic recombination between distinct genomic locations generates copy number diversity in human β-defensins

Science.gov (United States)

Bakar, Suhaili Abu; Hollox, Edward J.; Armour, John A. L.

2009-01-01

β-Defensins are small secreted antimicrobial and signaling peptides involved in the innate immune response of vertebrates. In humans, a cluster of at least 7 of these genes shows extensive copy number variation, with a diploid copy number commonly ranging between 2 and 7. Using a genetic mapping approach, we show that this cluster is at not 1 but 2 distinct genomic loci ≈5 Mb apart on chromosome band 8p23.1, contradicting the most recent genome assembly. We also demonstrate that the predominant mechanism of change in β-defensin copy number is simple allelic recombination occurring in the interval between the 2 distinct genomic loci for these genes. In 416 meiotic transmissions, we observe 3 events creating a haplotype copy number not found in the parent, equivalent to a germ-line rate of copy number change of ≈0.7% per gamete. This places it among the fastest-changing copy number variants currently known. PMID:19131514

Induced spherococcoid hard wheat

International Nuclear Information System (INIS)

Yanev, Sh.

1981-01-01

A mutant has been obtained - a spheroccocoid line -through irradiation of hard wheat seed with fast neutrons. It is distinguished by semispherical glumes and smaller grain; the plants have low stem with erect leaves but with shorter spikes and with lesser number of spikelets than those of the initial cultivar. Good productive tillering and resistance to lodging contributed to 23.5% higher yield. The line was superior to the standard and the initial cultivars by 14.2% as regards protein content, and by up to 22.8% - as to flour gluten. It has been successfully used in hybridization producing high-yielding hard wheat lines resistant to lodging, with good technological and other indicators. The possibility stated is of obtaining a spherococcoid mutant in tetraploid (hard) wheat out of the D-genome as well as its being suited to hard wheat breeding to enhance protein content, resistance to lodging, etc. (author)

Dinámicas territoriales de la industria automotriz argentina (1990-2012

Directory of Open Access Journals (Sweden)

Matías Donato Laborde

2014-06-01

Full Text Available El presente trabajo propone contribuir al análisis de las dinámicas territoriales vinculadas al funcionamiento de la industria automotriz argentina en los periodos de la convertibilidad y post convertibilidad. En este marco, se analizarán las principales características de la industria automotriz teniendo en cuenta las políticas públicas, las diferentes estrategias desplegadas por las empresas y los intercambios comerciales, asimismo se utilizan fuentes estadísticas del INDEC, la AFAC (Asociación de Fábricas Argentinas de Componentes y ADEFA (Asociación de Fábricas de Automotores.

Comportamiento dinámico de depósitos aluviales en Colombia

OpenAIRE

Guzmán, Adolfo; Nuñez, Jsús; Parra, Fernando

2006-01-01

En este artículo se presentan las principales características de dos arenas de origen aluvial (Tumaco y Cali) potencialmente licuables, que históricamente han sido sometidas a cargas dinámicas generadas por sismos. Los dos depósitos se encuentran ubicados en áreas de amenaza sísmica alta, por lo que las aceleraciones máximas esperadas en roca fluctúan entre 0.2g y 0.3g. La caracterización de los depósitos granulares se realizó mediante pruebas de campo, complementados con ensayos de laborator...

Getting DNA copy numbers without control samples.

Science.gov (United States)

Ortiz-Estevez, Maria; Aramburu, Ander; Rubio, Angel

2012-08-16

The selection of the reference to scale the data in a copy number analysis has paramount importance to achieve accurate estimates. Usually this reference is generated using control samples included in the study. However, these control samples are not always available and in these cases, an artificial reference must be created. A proper generation of this signal is crucial in terms of both noise and bias.We propose NSA (Normality Search Algorithm), a scaling method that works with and without control samples. It is based on the assumption that genomic regions enriched in SNPs with identical copy numbers in both alleles are likely to be normal. These normal regions are predicted for each sample individually and used to calculate the final reference signal. NSA can be applied to any CN data regardless the microarray technology and preprocessing method. It also finds an optimal weighting of the samples minimizing possible batch effects. Five human datasets (a subset of HapMap samples, Glioblastoma Multiforme (GBM), Ovarian, Prostate and Lung Cancer experiments) have been analyzed. It is shown that using only tumoral samples, NSA is able to remove the bias in the copy number estimation, to reduce the noise and therefore, to increase the ability to detect copy number aberrations (CNAs). These improvements allow NSA to also detect recurrent aberrations more accurately than other state of the art methods. NSA provides a robust and accurate reference for scaling probe signals data to CN values without the need of control samples. It minimizes the problems of bias, noise and batch effects in the estimation of CNs. Therefore, NSA scaling approach helps to better detect recurrent CNAs than current methods. The automatic selection of references makes it useful to perform bulk analysis of many GEO or ArrayExpress experiments without the need of developing a parser to find the normal samples or possible batches within the data. The method is available in the open-source R package

Din - Turizm İlişkisi Çerçevesinde Yahudilikte, Hıristiyanlıkta Ve İslamiyette Hac Uygulamasına Genel Bakış

OpenAIRE

Mehmet Alparslan Küçük

2013-01-01

Turizm sektörü, gerek dinî yaşam biçimi gerekse dinî kurumlar ile etkileşim ve iletişim halindedir. Bu etkileşim ve iletişim, dünyanın her yerinde görülebilmektedir. Turizm ile din arasındaki bu iletişim/etkileşim neticesinde inanç turizmi anlayışı ortaya çıkmıştır. İnanç Turizmi ile Hac arasında yakın bir ilişki sözkonusudur. Ancak Hac anlayışı ile inanç turizmi arasında ortak özellikler ile birlikte bazı farklılıklar da mevcuttur. Bu makalemizde bu benzerlikler ve farklılıklar ile birlikte ...

2TB hard disk drive

CERN Multimedia

This particular object was used up until 2012 in the Data Centre. It slots into one of the Disk Server trays. Hard disks were invented in the 1950s. They started as large disks up to 20 inches in diameter holding just a few megabytes (link is external). They were originally called "fixed disks" or "Winchesters" (a code name used for a popular IBM product). They later became known as "hard disks" to distinguish them from "floppy disks (link is external)." Hard disks have a hard platter that holds the magnetic medium, as opposed to the flexible plastic film found in tapes and floppies.

TEGS-CN: A Statistical Method for Pathway Analysis of Genome-wide Copy Number Profile.

Science.gov (United States)

Huang, Yen-Tsung; Hsu, Thomas; Christiani, David C

2014-01-01

The effects of copy number alterations make up a significant part of the tumor genome profile, but pathway analyses of these alterations are still not well established. We proposed a novel method to analyze multiple copy numbers of genes within a pathway, termed Test for the Effect of a Gene Set with Copy Number data (TEGS-CN). TEGS-CN was adapted from TEGS, a method that we previously developed for gene expression data using a variance component score test. With additional development, we extend the method to analyze DNA copy number data, accounting for different sizes and thus various numbers of copy number probes in genes. The test statistic follows a mixture of X (2) distributions that can be obtained using permutation with scaled X (2) approximation. We conducted simulation studies to evaluate the size and the power of TEGS-CN and to compare its performance with TEGS. We analyzed a genome-wide copy number data from 264 patients of non-small-cell lung cancer. With the Molecular Signatures Database (MSigDB) pathway database, the genome-wide copy number data can be classified into 1814 biological pathways or gene sets. We investigated associations of the copy number profile of the 1814 gene sets with pack-years of cigarette smoking. Our analysis revealed five pathways with significant P values after Bonferroni adjustment (number data, and causal mechanisms of the five pathways require further study.

Copy-Move Forgery Detection Technique for Forensic Analysis in Digital Images

Directory of Open Access Journals (Sweden)

Toqeer Mahmood

2016-01-01

Full Text Available Due to the powerful image editing tools images are open to several manipulations; therefore, their authenticity is becoming questionable especially when images have influential power, for example, in a court of law, news reports, and insurance claims. Image forensic techniques determine the integrity of images by applying various high-tech mechanisms developed in the literature. In this paper, the images are analyzed for a particular type of forgery where a region of an image is copied and pasted onto the same image to create a duplication or to conceal some existing objects. To detect the copy-move forgery attack, images are first divided into overlapping square blocks and DCT components are adopted as the block representations. Due to the high dimensional nature of the feature space, Gaussian RBF kernel PCA is applied to achieve the reduced dimensional feature vector representation that also improved the efficiency during the feature matching. Extensive experiments are performed to evaluate the proposed method in comparison to state of the art. The experimental results reveal that the proposed technique precisely determines the copy-move forgery even when the images are contaminated with blurring, noise, and compression and can effectively detect multiple copy-move forgeries. Hence, the proposed technique provides a computationally efficient and reliable way of copy-move forgery detection that increases the credibility of images in evidence centered applications.

Uma análise da dinâmica inflacionária brasileira

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Francisco Cribari-Neto

2005-12-01

Full Text Available O objetivo central do presente artigo é analisar a dinâmica inflacionária brasileira e medir o grau de inércia em tal dinâmica. De início, nós apresentamos resultados de simulação de Monte Carlo sobre o desempenho em amostras finitas de diferentes variantes da razão de variâncias, uma medida comumente utilizada para a mensuração de persistência de choques no longo prazo. As simulações são realizadas sob inovações normais e não-normais e também com e sem outliers e inliers. Os resultados favorecem uma particular variante robusta da razão de variâncias proposta neste artigo. Os resultados empíricos para o Brasil indicam que o grau de inércia inflacionária neste país é substancialmente maior do que aquele encontrado por Campêlo e Cribari-Neto (Revista Brasileira de Economia, 57, 713-739, 2003; de fato, em alguns períodos da história econômica brasileira recente nós encontramos inércia plena. Todavia, o grau de inércia inflacionária após a implementação do Plano Real é de segunda ordem. Nós analisamos também as dinâmicas inflacionárias da Argentina, Chile e México.The chief goal of this paper is to analyze the Brazilian inflationary dynamics, and to measure the degree of inertia in such dynamics. To that end, we start by reporting Monte Carlo simulation results on the finite-sample performance of different variants of the variance ratio, a well know measure of long-run persistence of shocks. The simulations are performed under normal and nonnormal innovations, and also with and without outliers and inliers. Overall, the results favor a robust variant of the variance ratio we propose. The empirical results for Brazil suggest that the degree of inertia in this country is substantially larger than what was found by Campêlo and Cribari-Neto (Revista Brasileira de Economia 57, 713-739, 2003; indeed, in several periods of the recent economic history we find full inertia. However, the degree of inertia since

Janka hardness using nonstandard specimens

Science.gov (United States)

David W. Green; Marshall Begel; William Nelson

2006-01-01

Janka hardness determined on 1.5- by 3.5-in. specimens (2×4s) was found to be equivalent to that determined using the 2- by 2-in. specimen specified in ASTM D 143. Data are presented on the relationship between Janka hardness and the strength of clear wood. Analysis of historical data determined using standard specimens indicated no difference between side hardness...

Ground deformation monitoring using RADARSAT-2 DInSAR-MSBAS at the Aquistore CO2 storage site in Saskatchewan (Canada)

Science.gov (United States)

Czarnogorska, M.; Samsonov, S.; White, D.

2014-11-01

The research objectives of the Aquistore CO2 storage project are to design, adapt, and test non-seismic monitoring methods for measurement, and verification of CO2 storage, and to integrate data to determine subsurface fluid distributions, pressure changes and associated surface deformation. Aquistore site is located near Estevan in Southern Saskatchewan on the South flank of the Souris River and west of the Boundary Dam Power Station and the historical part of Estevan coal mine in southeastern Saskatchewan, Canada. Several monitoring techniques were employed in the study area including advanced satellite Differential Interferometric Synthetic Aperture Radar (DInSAR) technique, GPS, tiltmeters and piezometers. The targeted CO2 injection zones are within the Winnipeg and Deadwood formations located at > 3000 m depth. An array of monitoring techniques was employed in the study area including advanced satellite Differential Interferometric Synthetic Aperture Radar (DInSAR) with established corner reflectors, GPS, tiltmeters and piezometers stations. We used airborne LIDAR data for topographic phase estimation, and DInSAR product geocoding. Ground deformation maps have been calculated using Multidimensional Small Baseline Subset (MSBAS) methodology from 134 RADARSAT-2 images, from five different beams, acquired during 20120612-20140706. We computed and interpreted nine time series for selected places. MSBAS results indicate slow ground deformation up to 1 cm/year not related to CO2 injection but caused by various natural and anthropogenic causes.

CONCENTRAŢIA ESTRADIOLULUI ŞI A TESTOSTERONULUI ÎN DIABETUL EXPERIMENTAL PE FONDALUL ADMINISTRĂRII EXTRACTULUI DIN CYNARA SCOLYMUS

Directory of Open Access Journals (Sweden)

Iurie BACALOV

2017-07-01

Full Text Available Diabetul zaharat apare din cauza producţei insuficiente de insulină de către pancreas; astfel, nivelul glucozei din sânge depăşeşte valorile normale. Statisticile arată o creștere permanentă a cazurilor de diabet zaharat. Circa 5% din populație (cu unele variații de la o țară la alta suferă de forma clinică a acestei maladii, aproximativ 10% – de forma ei subclinică. Diabetul zaharat produce o serie de dereglări funcţionale, precum și la nivelul gonadelor, ce pot duce la complicaţii grave, ca menopauza la femei şi impotența la bărbaţi.CONCENTRATION OF ESTRADIOL AND TESTOSTERONE IN EXPERIMENTAL DIABETES ON THE BACKGROUND OF CYNARA SCOLYMUS EXTRACT INTAKEDiabetes occurs due to insufficient insulin production by the pancreas, so the blood glucose level exceeds normal levels. Statistics show a permanent increase in diabetes cases. About 5% of the population (with some variation from one country to another suffers from the clinical form of this disease, about 10% - of its subclinical form. Diabetes causes a number of functional disorders, as well as on gonads, that can lead to serious complications such as menopause in women and impotence in men.

Herramienta para la enseñanza de las ecuaciones de Lagrange basada en la simulación de sistemas dinámicos

OpenAIRE

Bravo M., D. A.; Rengifo R., C. F.

2014-01-01

En este trabajo se propone una herramienta para la enseñanza de la mecánica clásica, modelando sistemas dinámicos con las ecuaciones de Lagrange, a partir de la simulación en Matlab ©. Este enfoque permite a los estudiantes de ingeniería y ciencias básicas, desarrollar competencias en programación, análisis numérico, con el uso de la física como herramienta fundamental para modelar y simular sistemas dinámicos complejos, como por ejemplo: robots industriales, robots bípedos y cualquier sistem...

18 CFR 385.2004 - Original and copies of filings (Rule 2004).

Science.gov (United States)

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Original and copies of... Requirements for Filings in Proceedings Before the Commission § 385.2004 Original and copies of filings (Rule 2004). Any person filing under this chapter must provide an original of the filing and fourteen exact...

17 CFR 270.24b-2 - Filing copies of sales literature.

Science.gov (United States)

2010-04-01

... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Filing copies of sales literature. 270.24b-2 Section 270.24b-2 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION... literature. Copies of material filed with the Commission for the sole purpose of complying with section 24(b...

Determining the Effect of Material Hardness During the Hard Turning of AISI4340 Steel

Science.gov (United States)

Kambagowni, Venkatasubbaiah; Chitla, Raju; Challa, Suresh

2018-05-01

In the present manufacturing industries hardened steels are most widely used in the applications like tool design and mould design. It enhances the application range of hard turning of hardened steels in manufacturing industries. This study discusses the impact of workpiece hardness, feed and depth of cut on Arithmetic mean roughness (Ra), root mean square roughness (Rq), mean depth of roughness (Rz) and total roughness (Rt) during the hard turning. Experiments have been planned according to the Box-Behnken design and conducted on hardened AISI4340 steel at 45, 50 and 55 HRC with wiper ceramic cutting inserts. Cutting speed is kept constant during this study. The analysis of variance was used to determine the effects of the machining parameters. 3-D response surface plots drawn based on RSM were utilized to set up the input-output relationships. The results indicated that the feed rate has the most significant parameter for Ra, Rq and Rz and hardness has the most critical parameter for the Rt. Further, hardness shows its influence over all the surface roughness characteristics.

Diseño, branding y dinámicas socioculturales

Directory of Open Access Journals (Sweden)

Alzate Sanz, Jaime Eduardo

2014-07-01

Full Text Available Actualmente, las regiones de conocimiento se caracterizan por ser territorios donde confluyen proyectos importantes que tienen que ver con las tecnologías, la cultura y el conocimiento. Las políticas de gobierno, el emprendimiento, el trabajo con el conocimiento proyectado desde las universidades y grupos de investigación alimentan constantemente la actividad cultural; a pesar de estas dinámicas, es posible que en muchas regiones de conocimiento el branding no se realice de manera rigurosa. De acuerdo a lo anterior, es importante reflexionar sobre la relación del diseño y el branding en las regiones eje de conocimiento, teniendo en cuenta la responsabilidad social de las marcas y la importancia del sujeto como integrante proactivo de la cultura

20 CFR 703.105 - Copies of forms of policies to be submitted with application.

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Copies of forms of policies to be submitted... REGULATIONS Authorization of Insurance Carriers § 703.105 Copies of forms of policies to be submitted with... of the Office copies of the forms of policies which the applicant proposes to issue in writing...

Haplotype phasing and inheritance of copy number variants in nuclear families.

Science.gov (United States)

Palta, Priit; Kaplinski, Lauris; Nagirnaja, Liina; Veidenberg, Andres; Möls, Märt; Nelis, Mari; Esko, Tõnu; Metspalu, Andres; Laan, Maris; Remm, Maido

2015-01-01

DNA copy number variants (CNVs) that alter the copy number of a particular DNA segment in the genome play an important role in human phenotypic variability and disease susceptibility. A number of CNVs overlapping with genes have been shown to confer risk to a variety of human diseases thus highlighting the relevance of addressing the variability of CNVs at a higher resolution. So far, it has not been possible to deterministically infer the allelic composition of different haplotypes present within the CNV regions. We have developed a novel computational method, called PiCNV, which enables to resolve the haplotype sequence composition within CNV regions in nuclear families based on SNP genotyping microarray data. The algorithm allows to i) phase normal and CNV-carrying haplotypes in the copy number variable regions, ii) resolve the allelic copies of rearranged DNA sequence within the haplotypes and iii) infer the heritability of identified haplotypes in trios or larger nuclear families. To our knowledge this is the first program available that can deterministically phase null, mono-, di-, tri- and tetraploid genotypes in CNV loci. We applied our method to study the composition and inheritance of haplotypes in CNV regions of 30 HapMap Yoruban trios and 34 Estonian families. For 93.6% of the CNV loci, PiCNV enabled to unambiguously phase normal and CNV-carrying haplotypes and follow their transmission in the corresponding families. Furthermore, allelic composition analysis identified the co-occurrence of alternative allelic copies within 66.7% of haplotypes carrying copy number gains. We also observed less frequent transmission of CNV-carrying haplotypes from parents to children compared to normal haplotypes and identified an emergence of several de novo deletions and duplications in the offspring.

Haplotype phasing and inheritance of copy number variants in nuclear families.

Directory of Open Access Journals (Sweden)

Priit Palta

Full Text Available DNA copy number variants (CNVs that alter the copy number of a particular DNA segment in the genome play an important role in human phenotypic variability and disease susceptibility. A number of CNVs overlapping with genes have been shown to confer risk to a variety of human diseases thus highlighting the relevance of addressing the variability of CNVs at a higher resolution. So far, it has not been possible to deterministically infer the allelic composition of different haplotypes present within the CNV regions. We have developed a novel computational method, called PiCNV, which enables to resolve the haplotype sequence composition within CNV regions in nuclear families based on SNP genotyping microarray data. The algorithm allows to i phase normal and CNV-carrying haplotypes in the copy number variable regions, ii resolve the allelic copies of rearranged DNA sequence within the haplotypes and iii infer the heritability of identified haplotypes in trios or larger nuclear families. To our knowledge this is the first program available that can deterministically phase null, mono-, di-, tri- and tetraploid genotypes in CNV loci. We applied our method to study the composition and inheritance of haplotypes in CNV regions of 30 HapMap Yoruban trios and 34 Estonian families. For 93.6% of the CNV loci, PiCNV enabled to unambiguously phase normal and CNV-carrying haplotypes and follow their transmission in the corresponding families. Furthermore, allelic composition analysis identified the co-occurrence of alternative allelic copies within 66.7% of haplotypes carrying copy number gains. We also observed less frequent transmission of CNV-carrying haplotypes from parents to children compared to normal haplotypes and identified an emergence of several de novo deletions and duplications in the offspring.

Dinâmica de populações em ambiente estocástico

OpenAIRE

Coelho Neto, Elias Dias

2014-01-01

Estudamos um modelo para dinâmica de duas populações interagentes, uma de presas e outra de predadores, sujeitas a um ruído aditivo, que pode ser interpretado como um termo de migração aleatória. Resolvemos numericamente as equações diferenciais estocásticas do modelo e comparamos os resultados com as soluções do modelo determinístico associado. Identificamos três comportamentos qualitativamente distintos, correspondentes a três tipos diferentes de pontos de equilíbrio do sistema determinísti...

Os programas de geometria dinâmica no ensino básico

OpenAIRE

Fonseca, Cecília; Mateus, Joaquim

2011-01-01

Tendo em conta o contexto informático actual, estão ao dispor dos intervenientes no processo de ensino/aprendizagem um vasto leque de programas que permitem diversificar estratégias no ensino/aprendizagem da matemática. É neste enquadramento que se inserem os programas de geometria dinâmica, os quais constituem ferramentas interactivas que permitem a criação e manipulação de figuras geométricas, com base nas suas propriedades, favorecendo a compreensão dos conceitos e relações geométricas. ...

Las Capacidades Dinámicas e Administración Estratégica

Directory of Open Access Journals (Sweden)

Vidigal Fernandes Martins

2011-09-01

Full Text Available Este ensayo teórico se centra en las teorías que explican cómo las organizaciones a obtener y mantener una ventaja competitiva. Tres Paradigmas se resumen, el paradigma y el paradigma de conflicto estratégico de Porter, y las conversaciones para poner fin al paradigma de recursos basado en recursos. "Capacidad dinámica" se derivan de la fuerte relación entre las nociones generalizadas de eficacia con respecto a los cambios y las fórmulas genéricas e la ventaja competitiva sustentable.

Agency Researchers' Perception of the Users and Uses of Copy Research.

Science.gov (United States)

Reid, Leonard N.; Salmon, Charles T.

A survey of 30 advertising agency researchers sought to determine (1) whether there are differences between agency researchers' perception of who benefits most from copy research and who should benefit most, and (2) whether there are differences between their perception of how copy research is used and how it should be used. Consistent with…

Career Dilemmas among Diné (Navajo College Graduates: An Exploration of the Dinétah (Navajo Nation Brain Drain

Directory of Open Access Journals (Sweden)

Avery Denny

2013-11-01

Full Text Available Like many Indigenous nations, the Navajo Nation has worked to develop its human and economic potential. It has provided scholarships and other supports to enable its members to pursue post-secondary education. However, relatively few of these college-educated members return to the reservation to contribute directly to its development. This phenomenon has been termed a brain drain. This study explored the experiences of 28 college-educated Navajos who, while raised on the reservation, were living off the reservation after completing their post-secondary education. Participants indicated a number of factors that went into their decision to live off the reservation. These included:1. Ké’: Relationships/Connections to Family, Culture, Homeland, People;2. Iiná: Lifestyle/Lifeway, Desirable Setting, Learned Work Ethic, Social Atmosphere, Togetherness (Diné vs. Individualism (Mainstream;Bee ach’į’ na’hwii’ná: Resources and Roadblocks to Making a Life, Infrastructure, Services, The “System”;3. Bee ajit’9: Opportunity, Prosperity and Personal Improvement, Education, Extracurricular, Job Availability, Work Experience.

Mathematical instrumentation in fourteenth-century Egypt and Syria the illustrated treatise of Najm al-Din al-Misri

CERN Document Server

Charette, F

2003-01-01

An illustrated Arabic treatise, with an English translation and detailed commentary, on the construction of over 100 various astronomical instruments, many of which are otherwise unknown to specialists. It was composed by Najm al-Din al-Misri, a rather shadowy figure, in Cairo around 1330 CE.

SU(3) lattice gauge fixing with overrelaxation and Gribov copies

Energy Technology Data Exchange (ETDEWEB)

Paciello, M.L.; Taglienti, B. (INFN La Sapienza, Rome (Italy)); Parrinello, C. (Physics Dept., New York Univ., NY (United States)); Petrarca, S. (Theory Div., CERN, Geneva (Switzerland)); Vladikas, A. (Dipt. di Fisica, Univ. Tor Vergata, Rome (Italy) INFN Tor Vergata, Rome (Italy))

1992-02-06

We report on the phenomenology of SU(3) lattice Landau gauge fixing as obtained by using an overrelaxation algorithm. An interesting result obtained using this very efficient algorithm is that distinct Gribov copies are generated by simply modifying the value {omega} of the overrelaxation parameter for a fixed starting configuration. By generating random gauge equivalent configurations, we study the variation of the number of copies with the lattice volume and gauge coupling. (orig.).

The copying power of one-state tree transducers

DEFF Research Database (Denmark)

Engelfriet, Joost; Skyum, Sven

1982-01-01

One-state deterministic top-down tree transducers (or, tree homomorphisms) cannot handle “prime copying,” i.e., their class of output (string) languages is not closed under the operation L → {$(w$)f(n) short parallel w ε L, f(n) greater-or-equal, slanted 1}, where f is any integer function whose...... range contains numbers with arbitrarily large prime factors (such as a polynomial). The exact amount of nonclosure under these copying operations is established for several classes of input (tree) languages. These results are relevant to the extended definable (or, restricted parallel level) languages......, to the syntax-directed translation of context-free languages, and to the tree transducer hierarchy....

Detailed data set of a large administration building as a validation model for DIN V18599-software; Umfangreicher Validierungsdatensatz eines grossen Verwaltungsgebaeudes fuer Software zur DIN V 18599

Energy Technology Data Exchange (ETDEWEB)

Hoettges, Kirsten; Woessner, Simon; de Boer, Jan; Erhorn, Hans [Fraunhofer-Institut fuer Bauphysik (IBP), Abt. Energiesysteme, Kassel (Germany); Fraunhofer-Institut fuer Bauphysik (IBP), Stuttgart (Germany)

2009-04-15

The calculation method of DIN V 18599 represents a very complex model for the estimation of the energy efficiency of buildings. The method is used for certificates too, thus, the number of users is quite high. This fact and the complexity of the method causes high demands on the related software products. Most of the end user software tools work with the calculation engine ibp18599kernel developed by Fraunhofer-Institut for Building Physics. There is a continuous quality control for both, the kernel and the user interfaces, i.e. the end user software. This paper gives an overview of the process of quality control as well as a documentation of a validation model used within this process, i.e. a complex administration building as a sample. (Abstract Copyright [2009], Wiley Periodicals, Inc.) [German] Mit dem Berechnungsverfahren der DIN V 18599 liegt ein umfassendes Berechnungsmodell fuer die energetische Bewertung von Gebaeuden vor. Der grosse Umfang der Verfahren stellt auch an die softwaretechnischen Umsetzungen fuer die Planungspraxis hohe Anforderungen. Das Fraunhofer-Institut fuer Bauphysik hat hierzu den Rechenkern ibp18599kernel entwickelt, der zwischenzeit-lich von zahlreichen Softwarehaeusern fuer Endanwendungsprogramme zur energetischen Bewertung und Erstellung von Energieausweisen eingesetzt wird. Dieser ''Rechenmotor'' unterliegt einer steten Qualitaetskontrolle zur Sicherstellung der Berechnungsgenauigkeit. Der vorliegende Aufsatz stellt den Prozess der Qualitaetssicherung anhand eines neuen Validierungsbeispiels in Form eines komplexen Verwaltungsgebaeudes vor. Die Fallstudie kann auch zur Validierung anderer Berechnungssysteme, die nicht auf dem Rechenkern basieren, genutzt werden. (Abstract Copyright [2009], Wiley Periodicals, Inc.)

Reconfiguração dinâmica de linhas de montagem

Directory of Open Access Journals (Sweden)

Ormeu Coelho da Silva Júnior

2010-04-01

Full Text Available Neste trabalho se propõe um novo problema envolvendo linhas de montagem. Nele se considera a necessidade de reconfiguração devido à mudança no tempo de ciclo requerido. Para tratá-lo, foram propostos quatro modelos de programação inteira mista, sendo três deles baseados em um horizonte de planejamento discretizado em períodos, o que dá ao problema um caráter dinâmico. Simultaneamente, força-se a suavização da carga de trabalho entre as estações, limitando-a com valores mínimos e máximos. Os modelos foram implementados em um pacote comercial de programação matemática e os resultados de alguns testes preliminares são reportados. Comparações entre o uso sucessivo de abordagens clássicas (tipo SALBP e a modelagem dinâmica demonstram a superioridade da abordagem proposta.In this paper we present a new problem involving assembly lines. It arises when successive variations in the cycle time force line re-configuration. We propose four mixed integer programming formulations for the problem, three of them using a time horizon divided in periods. Such assumption gives the problem a dynamic character. The models try to smooth the workload among the stations by forcing it to fall between minimum and maximum values predefined by the user. They were implemented in a commercial package for mathematical programming and some results are reported. Comparisons were made against the repetitive use of classical models (SALBP like to demonstrate the superiority of this new approach.

Exploiting rRNA operon copy number to investigate bacterial reproductive strategies.

Science.gov (United States)

Roller, Benjamin R K; Stoddard, Steven F; Schmidt, Thomas M

2016-09-12

The potential for rapid reproduction is a hallmark of microbial life, but microbes in nature must also survive and compete when growth is constrained by resource availability. Successful reproduction requires different strategies when resources are scarce and when they are abundant 1,2 , but a systematic framework for predicting these reproductive strategies in bacteria has not been available. Here, we show that the number of ribosomal RNA operons (rrn) in bacterial genomes predicts two important components of reproduction-growth rate and growth efficiency-which are favoured under contrasting regimes of resource availability 3,4 . We find that the maximum reproductive rate of bacteria doubles with a doubling of rrn copy number, and the efficiency of carbon use is inversely related to maximal growth rate and rrn copy number. We also identify a feasible explanation for these patterns: the rate and yield of protein synthesis mirror the overall pattern in maximum growth rate and growth efficiency. Furthermore, comparative analysis of genomes from 1,167 bacterial species reveals that rrn copy number predicts traits associated with resource availability, including chemotaxis and genome streamlining. Genome-wide patterns of orthologous gene content covary with rrn copy number, suggesting convergent evolution in response to resource availability. Our findings imply that basic cellular processes adapt in contrasting ways to long-term differences in resource availability. They also establish a basis for predicting changes in bacterial community composition in response to resource perturbations using rrn copy number measurements 5 or inferences 6,7 .

Dietary Variation and Evolution of Gene Copy Number among Dog Breeds.

Directory of Open Access Journals (Sweden)

Taylor Reiter

Full Text Available Prolonged human interactions and artificial selection have influenced the genotypic and phenotypic diversity among dog breeds. Because humans and dogs occupy diverse habitats, ecological contexts have likely contributed to breed-specific positive selection. Prior to the advent of modern dog-feeding practices, there was likely substantial variation in dietary landscapes among disparate dog breeds. As such, we investigated one type of genetic variant, copy number variation, in three metabolic genes: glucokinase regulatory protein (GCKR, phytanol-CoA 2-hydroxylase (PHYH, and pancreatic α-amylase 2B (AMY2B. These genes code for proteins that are responsible for metabolizing dietary products that originate from distinctly different food types: sugar, meat, and starch, respectively. After surveying copy number variation among dogs with diverse dietary histories, we found no correlation between diet and positive selection in either GCKR or PHYH. Although it has been previously demonstrated that dogs experienced a copy number increase in AMY2B relative to wolves during or after the dog domestication process, we demonstrate that positive selection continued to act on amylase copy number in dog breeds that consumed starch-rich diets in time periods after domestication. Furthermore, we found that introgression with wolves is not responsible for deterioration of positive selection on AMY2B among diverse dog breeds. Together, this supports the hypothesis that the amylase copy number expansion is found universally in dogs.

Seguimiento a la dinámica competitiva de dos grupos económicos colombianos

Directory of Open Access Journals (Sweden)

Carlos Rodríguez Romero

2007-06-01

Full Text Available Diferentes tipos de trabajos describen la importancia de la dinámica de multimercados para explicar cómo compiten las empresas que coinciden en diferentes sectores de su actividad. En este artículo se busca presentar inicialmente el cuerpo teórico que soporta la dinámica competitiva, para luego ejemplificar su aplicación en un estudio analítico que identifique las acciones competitivas, no sólo de los dos conglomerados colombianos más importantes, sino también de los individuos que se encuentran al mando de estas organizaciones. La investigación utiliza el análisis estructurado de contenido a través fuentes secundarias para identificar las acciones competitivas de las organizaciones estudiadas en el periodo de 1986-2002. De tal manera, se expondrá la lógica que utilizaron durante los últimos años esos dos grupos económicos en diversos mercados y cómo han aplicado sus estrategias competitivas, para rivalizar en sectores tan heterogéneos como la radio, la televisión, las gaseosas, las cervezas e incluso en el patrocinio de estrellas del deporte y la farándula nacional.

O Processo de Internacionalização como Elemento Gerador de Capacidades Dinâmicas: o caso da WEG na Argentina e na ChinaThe Internationalization Process as Generator Element of Dynamic Capacities: the case of WEG in Argentina and ChinaEl Proceso de Internacionalización como Elemento Generador de Capacidades Dinámicas: el caso de WEG en Argentina y China

Directory of Open Access Journals (Sweden)

FLEURY, Maria Tereza Leme

2009-12-01

Full Text Available RESUMOO artigo tem o objetivo de investigar as capacidades dinâmicas desenvolvidas e utilizadas pela WEG no processo de internacionalização e explicar como essas capacidades contribuem para que a empresa defenda e sustente a vantagem competitiva. De forma mais específica, o artigo apresenta um estudo exploratório por meio do caso do processo de internacionalização da empresa WEG na Argentina e na China. Tal artigo, tendo como enfoque de análise as capacidades dinâmicas, contribui à literatura de gestão internacional em dois aspectos. Primeiro, acrescenta o olhar analítico da internacionalização baseado em capacidades dinâmicas que ainda é bem restrito. Segundo, ao trabalhar as capacidades dinâmicas como elemento central da análise do processo de internacionalização propõe um framework de análise integrativo das teorias econômica e comportamental que são muito usadas para explicar o processo de internacionalização de empresas, porém são tratadas de maneira independente e por vezes antagônica. O resultado mostra como as capacidades dinâmicas são articuladas no caso da WEG no processo de internacionalização para a Argentina e o subsequente movimento para a China. As capacidades dinâmicas desenvolvidas na Argentina foram adquiridas pela matriz brasileira e puderam ser aplicadas com as devidas proporções no processo de internacionalização para a China. Entretanto, não pode ser identificado uma estrutura organizacional mais complexa em que os relacionamentos diretos inter-subsidiárias pudessem compartilhar capacidades dinâmicas como proposto no framework.ABSTRACTThe objective of the article is to research the dynamic capacities developed and used by WEG in its internationalization process and to explain how these capacities help the company defends and supports competitive advantage. The article presents an exploratory study of the internationalization process of WEG in Argentina and China. This article has as

46 CFR Sec. 5 - Responsibility for duplicating copies of NSA-WORKSMALREP Contract.

Science.gov (United States)

2010-10-01

... 46 Shipping 8 2010-10-01 2010-10-01 false Responsibility for duplicating copies of NSA-WORKSMALREP Contract. Sec. 5 Section 5 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION A-NATIONAL... INDIVIDUAL CONTRACT FOR MINOR REPAIRS-NSA-WORKSMALREP Sec. 5 Responsibility for duplicating copies of NSA...

Measurement of locus copy number by hybridisation with amplifiable probes

Science.gov (United States)

Armour, John A. L.; Sismani, Carolina; Patsalis, Philippos C.; Cross, Gareth

2000-01-01

Despite its fundamental importance in genome analysis, it is only recently that systematic approaches have been developed to assess copy number at specific genetic loci, or to examine genomic DNA for submicroscopic deletions of unknown location. In this report we show that short probes can be recovered and amplified quantitatively following hybridisation to genomic DNA. This simple observation forms the basis of a new approach to determining locus copy number in complex genomes. The power and specificity of multiplex amplifiable probe hybridisation is demonstrated by the simultaneous assessment of copy number at a set of 40 human loci, including detection of deletions causing Duchenne muscular dystrophy and Prader–Willi/Angelman syndromes. Assembly of other probe sets will allow novel, technically simple approaches to a wide variety of genetic analyses, including the potential for extension to high resolution genome-wide screens for deletions and amplifications. PMID:10606661

Measurement of locus copy number by hybridisation with amplifiable probes.

Science.gov (United States)

Armour, J A; Sismani, C; Patsalis, P C; Cross, G

2000-01-15

Despite its fundamental importance in genome analysis, it is only recently that systematic approaches have been developed to assess copy number at specific genetic loci, or to examine genomic DNA for submicro-scopic deletions of unknown location. In this report we show that short probes can be recovered and amplified quantitatively following hybridisation to genomic DNA. This simple observation forms the basis of a new approach to determining locus copy number in complex genomes. The power and specificity of multiplex amplifiable probe hybridisation is demonstrated by the simultaneous assessment of copy number at a set of 40 human loci, including detection of deletions causing Duchenne muscular dystrophy and Prader-Willi/Angelman syndromes. Assembly of other probe sets will allow novel, technically simple approaches to a wide variety of genetic analyses, including the potential for extension to high resolution genome-wide screens for deletions and amplifications.

77 FR 27125 - Periodicals-Recognition of Distribution of Periodicals via Electronic Copies

Science.gov (United States)

2012-05-09

... Electronic Copies AGENCY: Postal Service\\TM\\. ACTION: Final rule. SUMMARY: The Postal Service will revise the Mailing Standards of the United States Postal Service, Domestic Mail Manual (DMM[supreg]) 707.6 to permit limited reporting of electronic copies of Periodicals publications to satisfy the circulation standards...

Dinámica de inventarios y dinero bajo competencia monopolística y salarios de eficiencia

OpenAIRE

Escudé, Guillermo

1988-01-01

En este trabajo construyo un modelo IS-LM dinámico basado en la idea de que las empresas mantienen inventarios de productos terminados que actúan como un "colchón" absorbente de posibles desequilibrios en el mercado de productos. (Párrafo extraído del texto a modo de resumen) Instituto de Investigaciones Económicas

Adaptação voluntária do andar em idosos com doença de Parkinson sob dica visual dinâmica

OpenAIRE

Silveira, Carolina Rodrigues Alves [UNESP

2007-01-01

A capacidade de ajustar a velocidade de progressão é um importante mecanismo que adapta a atividade locomotora para mudanças nas demandas do ambiente. Essa capacidade está comprometida na doença de Parkinson e dicas visuais dinâmicas são efetivas na melhora da locomoção. Neste contexto, o objetivo do presente estudo foi analisar a influência da dica visual dinâmica, em diferentes condições de velocidade, no padrão do andar de indivíduos com doença de Parkinson. Para tanto, 15 idosos com doenç...

Getting DNA copy numbers without control samples

Directory of Open Access Journals (Sweden)

Ortiz-Estevez Maria

2012-08-01

Full Text Available Abstract Background The selection of the reference to scale the data in a copy number analysis has paramount importance to achieve accurate estimates. Usually this reference is generated using control samples included in the study. However, these control samples are not always available and in these cases, an artificial reference must be created. A proper generation of this signal is crucial in terms of both noise and bias. We propose NSA (Normality Search Algorithm, a scaling method that works with and without control samples. It is based on the assumption that genomic regions enriched in SNPs with identical copy numbers in both alleles are likely to be normal. These normal regions are predicted for each sample individually and used to calculate the final reference signal. NSA can be applied to any CN data regardless the microarray technology and preprocessing method. It also finds an optimal weighting of the samples minimizing possible batch effects. Results Five human datasets (a subset of HapMap samples, Glioblastoma Multiforme (GBM, Ovarian, Prostate and Lung Cancer experiments have been analyzed. It is shown that using only tumoral samples, NSA is able to remove the bias in the copy number estimation, to reduce the noise and therefore, to increase the ability to detect copy number aberrations (CNAs. These improvements allow NSA to also detect recurrent aberrations more accurately than other state of the art methods. Conclusions NSA provides a robust and accurate reference for scaling probe signals data to CN values without the need of control samples. It minimizes the problems of bias, noise and batch effects in the estimation of CNs. Therefore, NSA scaling approach helps to better detect recurrent CNAs than current methods. The automatic selection of references makes it useful to perform bulk analysis of many GEO or ArrayExpress experiments without the need of developing a parser to find the normal samples or possible batches within the

On scale dependence of hardness

International Nuclear Information System (INIS)

Shorshorov, M.Kh.; Alekhin, V.P.; Bulychev, S.I.

1977-01-01

The concept of hardness as a structure-sensitive characteristic of a material is considered. It is shown that in conditions of a decreasing stress field under the inventor the hardness function is determined by the average distance, Lsub(a), between the stops (fixed and sessile dislocations, segregation particles, etc.). In the general case, Lsub(a) depends on the size of the impression and explains the great diversity of hardness functions. The concept of average true deformation rate on depression is introduced

28 CFR 5.1101 - Copies of the Report of the Attorney General.

Science.gov (United States)

2010-07-01

... Attorney General. Copies of the Report of the Attorney General to the Congress on the Administration of the... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Copies of the Report of the Attorney General. 5.1101 Section 5.1101 Judicial Administration DEPARTMENT OF JUSTICE ADMINISTRATION AND...

Micro-hardness of non-irradiated uranium dioxide

International Nuclear Information System (INIS)

Kim, Sung-Sik; Takagi, Osamu; Obata, Naomi; Kirihara, Tomoo.

1983-01-01

In order to obtain the optimum conditions for micro-hardness measurements of sintered UO 2 , two kinds of hardness tests (Vickers and Knoop) were examined with non-irradiated UO 2 of 2.5 and 5 μm in grain size. The hardness values were obtained as a function of the applied load in the load range of 25 -- 1,000 g. In the Vickers test, cracks were generated around the periphery of an indentation even at lower load of 50 g, which means the Vickers hardness is not suitable for UO 2 specimens. In the Knoop test, three stages of load dependence were observed for sintered pellet as well as for a single crystal by Bates. Load dependence of Knoop hardness and crack formation were discussed. In the range of applied load around 70 -- 100 g there were plateau region where hardness values were nearly unchanged and did not contain any cracks in the indentation. The plateau region represents a hardness of a specimen. From a comparison between the hardness values of 2.5 μm and those of 5 μm UO 2 , it was approved that the degree of sintering controls the hardness in the plateau region. (author)

Predicción de los precios de contratos de electricidad usando una red neuronal con arquitectura dinámica

Directory of Open Access Journals (Sweden)

Juan David Velásquez Henao

2010-04-01

Full Text Available Los contratos en los mercados liberalizados de electricidad constituyen una herramienta para proteger a los agentes de la volatilidad; en este contexto, los pronósticos de los precios son una entrada clave para la toma de decisiones estratégicas y operativas de los agentes. En este artículo, se pronostican los precios promedios de los contratos despachados en el mercado eléctrico colombiano, usando una red neuronal con arquitectura dinámica conocida como DAN2. El modelo desarrollado es capaz de capturar la dinámica intrínseca de la serie de precios y de pronosticar el precio para el siguiente mes con más precisión que la metodología ARIMA clásica, para horizontes de predicción de 12 y 24 meses

The Home Copying Loophole Widens: Sony & Others v . Easyinternetcafé

OpenAIRE

Free, Dominic; Garnett, Nic

2003-01-01

The record industry is engaged in a determined campaign to stop the unlawful copying of music files downloaded via the Internet. In Sony & Others v. Easyinternetcafé [2003] All ER(D) 249 proceedings were brought by several major record companies to prevent Easyinternetcafé from providing a service copying music files onto CDs for its customers. The claimants succeeded in their aim. However the summary judgment which they obtained had a sting in the tail. It supports the proposition that t...

77 FR 21453 - Approval and Promulgation of Air Quality Implementation Plans; Colorado; Revisions to New Source...

Science.gov (United States)

2012-04-10

... Electric Power Company court ruling) and added definitions and provisions that have been incorporated into... available only in hard copy form. Publicly available docket materials are available either electronically through www.regulations.gov or in hard copy at the Air Program, Environmental Protection Agency (EPA...

77 FR 24982 - Privacy Act of 1974; System of Records

Science.gov (United States)

2012-04-26

... that documentary (physical, ``hard copies,'' paper, etc.) records are maintained in the same method as.... ADDRESSES: The public, Office of Management and Budget (OMB), and Congress are invited to submit [[Page...), storage area networks, or tape backup systems. Documentary (physical, ``hard copies,'' paper, etc...

32 CFR 286.4 - Policy.

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2010-07-01

... (d)(3) of this section), an opportunity to limit in writing hard copy, facsimile, or electronically... where creation of a record, programming, or particular format are questionable, Components should apply... hard copy for public access at Combatant Commands' respective locations. (l) Records management. FOIA...

40 CFR 94.509 - Maintenance of records; submittal of information.

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2010-07-01

... all testing. Records may be retained as hard copy (i.e., on paper) or reduced to microfilm, floppy... procedure; provided, that in every case, all the information contained in the hard copy is retained. (c) The... production line testing using an EPA information format. ...

76 FR 38977 - Approval and Promulgation of Air Quality Implementation Plans, State of Louisiana

Science.gov (United States)

2011-07-05

... submitted by the State of Louisiana, and include formatting changes, regulatory wording changes, substantive... other material, such as copyrighted material will be publicly available only in hard copy. Publicly available docket materials are available either electronically in http://www.regulations.gov or in hard copy...

76 FR 2263 - Approval and Promulgation of Air Quality Implementation Plans; Minnesota; Gopher Resource, LLC

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2011-01-13

... material, will be publicly available only in hard copy. Publicly available docket materials are available either electronically in http://www.regulations.gov or in hard copy at the Environmental Protection... because there are no significant emissions changes that stem from formatting, rewording, or clarifications...

78 FR 55037 - Approval and Promulgation of Implementation Plans; Texas; Attainment Demonstration for the...

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2013-09-09

... material, such as copyrighted material, will be publicly available only in hard copy. Publicly available docket materials are available either electronically in www.regulations.gov or in hard copy at the Air...-substantive revisions throughout to correct typographical errors and Texas Register formatting requirements...

75 FR 27821 - Privacy Act of 1974; System of Records

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2010-05-18

...-USNCB. The files contain electronic and hard copy records containing identifying particulars about... safety from persons, events, or things; investigative notes; computer printouts; letters; memoranda...: Case files closed as of April 5, 1982 and thereafter are disposed of as follows: The hard copy (paper...

78 FR 76064 - Approval and Promulgation of Air Quality Implementation Plans; Michigan

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2013-12-16

... Environmental Quality (MDEQ) submitted the revisions to address, among other things, the Federal NSR reform... will be publicly available only in hard copy form. Publicly available docket materials are available either electronically through www.regulations.gov or in hard copy at the Environmental Protection Agency...

Hard-hat day

CERN Multimedia

2003-01-01

CERN will be organizing a special information day on Friday, 27th June, designed to promote the wearing of hard hats and ensure that they are worn correctly. A new prevention campaign will also be launched.The event will take place in the hall of the Main Building from 11.30 a.m. to 2.00 p.m., when you will be able to come and try on various models of hard hat, including some of the very latest innovative designs, ask questions and pass on any comments and suggestions.

Evidence for the existence of Gribov copies in Landau gauge lattice QCD

Energy Technology Data Exchange (ETDEWEB)

Marinari, E.; Ricci, R. (Rome-2 Univ. (Italy). Dipt. di Fisica INFN, Rome (Italy)); Parrinello, C. (New York Univ., NY (USA). Physics Dept.)

1991-09-16

We unambiguously show the existence of Gribov copies in a pure SU(3) gauge lattice model, with Wilson action. We show that the usual steepest-descent algorithms used for implementing the lattice Landau gauge lead to ambiguities, which are related to the existence of Gribov copies in the model. (orig.).

40 CFR 267.53 - Who must have copies of the contingency plan?

Science.gov (United States)

2010-07-01

... contingency plan? 267.53 Section 267.53 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... UNDER A STANDARDIZED PERMIT Contingency Plan and Emergency Procedures § 267.53 Who must have copies of the contingency plan? (a) You must maintain a copy of the plan with all revisions at the facility; and...

Local Reasoning about a Copying Garbage Collector

DEFF Research Database (Denmark)

Torp-Smith, Noah; Birkedal, Lars; Reynolds, John C.

2008-01-01

We present a programming language, model, and logic appropriate for implementing and reasoning about a memory management system. We state semantically what is meant by correctness of a copying garbage collector, and employ a variant of the novel separation logics to formally specify partial corre...

La personalidad de las sociedades : descripción y dinámica

OpenAIRE

Amigó Borrás, Salvador; Caselles Moncho, Antonio; Micó i Ruiz, Joan Carles

2018-01-01

La Extraversión es considerada como la dimensión fundamental y básica de la personalidad desde la Teoría del Rasgo Único de Personalidad [1]. La Extraversión, como dimensión temperamental, engloba dimensiones cognitivas como la racionalidad y la emocionalidad. La teoría de los tipos de Carl Jung [2] establece una dinámica compleja entre estas dimensiones, a partir de la cual se obtiene una tipología de la personalidad. Amigó [3] adaptó la teoría de Jung para aplicarla a las sociedades. Así, a...

Genome Architecture and Its Roles in Human Copy Number Variation

Directory of Open Access Journals (Sweden)

Lu Chen

2014-12-01

Full Text Available Besides single-nucleotide variants in the human genome, large-scale genomic variants, such as copy number variations (CNVs, are being increasingly discovered as a genetic source of human diversity and the pathogenic factors of diseases. Recent experimental findings have shed light on the links between different genome architectures and CNV mutagenesis. In this review, we summarize various genomic features and discuss their contributions to CNV formation. Genomic repeats, including both low-copy and high-copy repeats, play important roles in CNV instability, which was initially known as DNA recombination events. Furthermore, it has been found that human genomic repeats can also induce DNA replication errors and consequently result in CNV mutations. Some recent studies showed that DNA replication timing, which reflects the high-order information of genomic organization, is involved in human CNV mutations. Our review highlights that genome architecture, from DNA sequence to high-order genomic organization, is an important molecular factor in CNV mutagenesis and human genomic instability.

SATISFACŢIA ÎN MUNCĂ ŞI VALORILE PROFESIONALE LA CADRELE DIDACTICE DIN INSTITUŢIILE DE ÎNVĂŢĂMÂNT PREŞCOLARE

Directory of Open Access Journals (Sweden)

Angela POTÂNG

2016-12-01

Full Text Available Studiul urmăreşte analiza gradului de satisfacţie profesională a cadrelor didactice din învăţământul preşcolar în func­ţie de orientarea lor valorică şi ierarhizarea valorilor profesionale. Noutatea şi originalitatea ştiinţifică este reprezentată de trasarea unor perspective noi de abordare a problemei privind satisfacţia în muncă a cadrului didactic din instituţiile preşcolare. Cercetarea respectivă poate deveni un suport metodologic pentru studenţii facultăţilor pedagogice, dar şi pentru managerii şi educatorii din grădiniţe.THE JOB SATISFACTION AND PROFESSIONAL VALUES TO TEACHERS IN PRESCHOOL EDUCATIONThe study aims to analyze the degree of satisfaction of teachers of preschool education according to their hierarchy of values and professional values. Scientific novelty: drawing new perspectives to tackle job satisfaction of teachers in preschools. This research can become a teaching methodological support for the students, but also for managers and kindergarten educators.

Accurate, high-throughput typing of copy number variation using paralogue ratios from dispersed repeats.

Science.gov (United States)

Armour, John A L; Palla, Raquel; Zeeuwen, Patrick L J M; den Heijer, Martin; Schalkwijk, Joost; Hollox, Edward J

2007-01-01

Recent work has demonstrated an unexpected prevalence of copy number variation in the human genome, and has highlighted the part this variation may play in predisposition to common phenotypes. Some important genes vary in number over a high range (e.g. DEFB4, which commonly varies between two and seven copies), and have posed formidable technical challenges for accurate copy number typing, so that there are no simple, cheap, high-throughput approaches suitable for large-scale screening. We have developed a simple comparative PCR method based on dispersed repeat sequences, using a single pair of precisely designed primers to amplify products simultaneously from both test and reference loci, which are subsequently distinguished and quantified via internal sequence differences. We have validated the method for the measurement of copy number at DEFB4 by comparison of results from >800 DNA samples with copy number measurements by MAPH/REDVR, MLPA and array-CGH. The new Paralogue Ratio Test (PRT) method can require as little as 10 ng genomic DNA, appears to be comparable in accuracy to the other methods, and for the first time provides a rapid, simple and inexpensive method for copy number analysis, suitable for application to typing thousands of samples in large case-control association studies.

Small Vocabulary with Saliency Matching for Video Copy Detection

DEFF Research Database (Denmark)

Ren, Huamin; Moeslund, Thomas B.; Tang, Sheng

2013-01-01

The importance of copy detection has led to a substantial amount of research in recent years, among which Bag of visual Words (BoW) plays an important role due to its ability to effectively handling occlusion and some minor transformations. One crucial issue in BoW approaches is the size of vocab......The importance of copy detection has led to a substantial amount of research in recent years, among which Bag of visual Words (BoW) plays an important role due to its ability to effectively handling occlusion and some minor transformations. One crucial issue in BoW approaches is the size...... matching algorithm based on salient visual words selection. More specifically, the variation of visual words across a given video are represented as trajectories and those containing locally asymptotically stable points are selected as salient visual words. Then we attempt to measure the similarity of two...... videos through saliency matching merely based on the selected salient visual words to remove false positives. Our experiments show that a small codebook with saliency matching is quite competitive in video copy detection. With the incorporation of the proposed saliency matching, the precision can...

Tragedy and Delirium in Montevideo: The Theater of Copi

Directory of Open Access Journals (Sweden)

Stefano Casi

2017-11-01

Full Text Available Nelle sue pièces comiche il drammaturgo franco-argentino Copi (1939-1987 si confronta con la tragedia, immergendo riferimenti e forme tragiche nell’umorismo e nel camp, all’interno di una cornice caratterizzata dal relativismo più estremo, in cui vita e morte coincidono e in cui ogni personaggio (spesso transgender afferma e nega la propria identità. Gli ‘eroi’ di Copi mostrano un difetto di volontà, che porta i loro sforzi titanici a diventare perdenti e a infrangersi contro risultati ridicoli o contro lo stallo. Le pièces oscillano tra «circo» e «tragedia», come dice il protagonista di Cachafaz (1981, definita dall’autore «tragedia barbara», in cui la tradizione del gauchesco argentino si coniuga con una visione cruenta e soprannaturale della tragedia, tra Macbeth e Le baccanti. Il linguaggio della commedia umoristica e camp è la base per la ricostruzione di un nuovo linguaggio tragico, e l’intero corpus teatrale di Copi non si presenta come parodia o dissacrazione, bensì come ‘riattivazione’ della tragedia nel secolo della sua ‘morte’ (Steiner.

37 CFR 360.25 - Copies of claims.

Science.gov (United States)

2010-07-01

... Section 360.25 Patents, Trademarks, and Copyrights COPYRIGHT ROYALTY BOARD, LIBRARY OF CONGRESS SUBMISSION OF ROYALTY CLAIMS FILING OF CLAIMS TO ROYALTY FEES COLLECTED UNDER COMPULSORY LICENSE Digital Audio Recording Devices and Media Royalty Claims § 360.25 Copies of claims. A claimant shall, for each claim...

37 CFR 360.5 - Copies of claims.

Science.gov (United States)

2010-07-01

... Section 360.5 Patents, Trademarks, and Copyrights COPYRIGHT ROYALTY BOARD, LIBRARY OF CONGRESS SUBMISSION OF ROYALTY CLAIMS FILING OF CLAIMS TO ROYALTY FEES COLLECTED UNDER COMPULSORY LICENSE Cable Claims... hand delivery or by mail, file an original and one copy of the claim to cable royalty fees. ...

37 CFR 203.5 - Inspection and copying.

Science.gov (United States)

2010-07-01

... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Inspection and copying. 203.5 Section 203.5 Patents, Trademarks, and Copyrights COPYRIGHT OFFICE, LIBRARY OF CONGRESS COPYRIGHT OFFICE AND PROCEDURES FREEDOM OF INFORMATION ACT: POLICIES AND PROCEDURES Availability of Information § 203.5...

Standard test methods for rockwell hardness of metallic materials

CERN Document Server

American Society for Testing and Materials. Philadelphia

2008-01-01

1.1 These test methods cover the determination of the Rockwell hardness and the Rockwell superficial hardness of metallic materials by the Rockwell indentation hardness principle. This standard provides the requirements for Rockwell hardness machines and the procedures for performing Rockwell hardness tests. 1.2 This standard includes additional requirements in annexes: Verification of Rockwell Hardness Testing Machines Annex A1 Rockwell Hardness Standardizing Machines Annex A2 Standardization of Rockwell Indenters Annex A3 Standardization of Rockwell Hardness Test Blocks Annex A4 Guidelines for Determining the Minimum Thickness of a Test Piece Annex A5 Hardness Value Corrections When Testing on Convex Cylindrical Surfaces Annex A6 1.3 This standard includes nonmandatory information in appendixes which relates to the Rockwell hardness test. List of ASTM Standards Giving Hardness Values Corresponding to Tensile Strength Appendix X1 Examples of Procedures for Determining Rockwell Hardness Uncertainty Appendix X...

Standard test methods for rockwell hardness of metallic materials

CERN Document Server

American Society for Testing and Materials. Philadelphia

2011-01-01

1.1 These test methods cover the determination of the Rockwell hardness and the Rockwell superficial hardness of metallic materials by the Rockwell indentation hardness principle. This standard provides the requirements for Rockwell hardness machines and the procedures for performing Rockwell hardness tests. 1.2 This standard includes additional requirements in annexes: Verification of Rockwell Hardness Testing Machines Annex A1 Rockwell Hardness Standardizing Machines Annex A2 Standardization of Rockwell Indenters Annex A3 Standardization of Rockwell Hardness Test Blocks Annex A4 Guidelines for Determining the Minimum Thickness of a Test Piece Annex A5 Hardness Value Corrections When Testing on Convex Cylindrical Surfaces Annex A6 1.3 This standard includes nonmandatory information in appendixes which relates to the Rockwell hardness test. List of ASTM Standards Giving Hardness Values Corresponding to Tensile Strength Appendix X1 Examples of Procedures for Determining Rockwell Hardness Uncertainty Appendix X...

Entropía proporcional de la dinámica cardiaca aplicada al diagnóstico de pacientes de la Unidad de Cuidados Intensivos

Directory of Open Access Journals (Sweden)

Javier Rodríguez

2013-03-01

Full Text Available La teoría de sistemas dinámicos cuantifica los estados y la evolución de los sistemas. Con base en esta teoría se creó una nueva metodología que cuantifica parejas ordenadas de frecuencias cardiacas en el espacio de fases de mediante la probabilidad y proporciones de la entropía, diferenciando clínicamente normalidad, enfermedad crónica, aguda, y evolución. Se registraron frecuencias cardiacas y latidos totales cada hora en 40 Holter de pacientes hospitalizados en la Unidad de Cuidados Coronarios, se realizó una simulación computacional para construir atractores caóticos y se evaluó la probabilidad, la entropía no equiprobable, y las proporciones de la entropía para la ocupación espacial de cada atractor, realizando comparaciones entre el diagnóstico clínico y el obtenido a través de la metodología físico matemática. Se evidenció que la metodología detecta en todos los casos el estado patológico de la dinámica, obteniendo valores de sensibilidad y especificidad de 100% y coeficiente Kappa de 1, evidenciando que es posible además establecer cuantitativamente la gravedad del mismo. Los resultados confirman que la autoorganización física y matemática de la dinámica cardiaca reflejada en el atractor dinámico geométrico, permite establecer predicciones de aplicación clínica en pacientes de la Unidad de Cuidados Coronarios.

Performance of Molecular Inversion Probes (MIP) in Allele CopyNumber Determination

Energy Technology Data Exchange (ETDEWEB)

Wang, Yuker; Moorhead, Martin; Karlin-Neumann, George; Wang,Nicolas J.; Ireland, James; Lin, Steven; Chen, Chunnuan; Heiser, LauraM.; Chin, Koei; Esserman, Laura; Gray, Joe W.; Spellman, Paul T.; Faham,Malek

2007-05-14

We have developed a new protocol for using MolecularInversion Probes (MIP) to accurately and specifically measure allele copynumber (ACN). The new protocol provides for significant improvementsincluding the reduction of input DNA (from 2?g) by more than 25 fold (to75ng total genomic DNA), higher overall precision resulting in one orderof magnitude lower false positive rate, and greater dynamic range withaccurate absolute copy number up to 60 copies.

Copy-number variants in neurodevelopmental disorders: promises and challenges.

LENUS (Irish Health Repository)

Merikangas, Alison K

2012-02-01

Copy-number variation (CNV) is the most prevalent type of structural variation in the human genome. There is emerging evidence that copy-number variants (CNVs) provide a new vista on understanding susceptibility to neuropsychiatric disorders. Some challenges in the interpretation of current CNV studies include the use of overlapping samples, differing phenotypic definitions, an absence of population norms for CNVs and a lack of consensus in methods for CNV detection and analysis. Here, we review current CNV association study methods and results in autism spectrum disorders (ASD) and schizophrenia, and provide suggestions for design approaches to future studies that might maximize the translation of this work to etiological understanding.

77 FR 71145 - Approval and Promulgation of Implementation Plans; New Mexico; New Source Review (NSR...

Science.gov (United States)

2012-11-29

... material, such as copyrighted material, will be publicly available only in hard copy. Publicly available docket materials are available either electronically in http://www.regulations.gov or in hard copy at the... renumbering of several existing sections and formatting changes that were made throughout the entire Part...

76 FR 64240 - Approval and Promulgation of Implementation Plans; North Carolina: Prevention of Significant...

Science.gov (United States)

2011-10-18

... and will be publicly available only in hard copy form. Publicly available docket materials are available either electronically through http://www.regulations.gov or in hard copy at the Regulatory... revision on May 17, 2011. In its final SIP revision, North Carolina made minor [[Page 64241

75 FR 35660 - Massachusetts: Final Authorization of State Hazardous Waste Management Program Revisions

Science.gov (United States)

2010-06-23

... copyrighted material, is not placed on the Internet and will be publicly available only in hard copy form... hard copy at the following two locations: (i) Massachusetts Department of Environmental Protection...: dredged material exemption at 40 CFR 261.4(g)--State: formatting corrections to previously authorized...

76 FR 10544 - Approval and Promulgation of Air Quality Implementation Plans, State of Louisiana

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2011-02-25

..., were submitted by the State of Louisiana, and include formatting changes, regulatory wording changes... available only in hard copy. Publicly available docket materials are available either electronically in http://www.regulations.gov or in hard copy at the Air Planning Section (6PD- L), Environmental Protection...

76 FR 51314 - Approval and Promulgation of Air Quality Implementation Plans; Maryland; Adoption of Drum and...

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2011-08-18

... publicly available only in hard copy form. Publicly available docket materials are available either electronically in http://www.regulations.gov or in hard copy during normal business hours at the Air Protection... sources, including drum and pail coatings. In developing these CTGs, EPA, among other things, evaluated...

76 FR 60820 - Draft Integrated Science Assessment for Ozone and Related Photochemical Oxidants

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2011-09-30

... other things, ``cause or contribute to air pollution which may reasonably be anticipated to endanger.... Certain other materials, such as copyrighted material, are publicly available only in hard copy. Publicly available docket materials are available either electronically in http://www.regulations.gov or in hard copy...

77 FR 72287 - Approval and Promulgation of Implementation Plans; Florida; 110(a)(2)(D)(i)(II) Infrastructure...

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2012-12-05

... available only in hard copy form. Publicly available docket materials are available either electronically in www.regulations.gov or in hard copy at the Regulatory Development Section, Air Planning Branch, Air... decree with Earthjustice which required EPA, among other things, to complete a Federal Register notice...

78 FR 57496 - Approval and Promulgation of Air Quality Implementation Plans; State of Colorado Second Ten-Year...

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2013-09-19

... FURTHER INFORMATION CONTACT section to view the hard copy of the docket. You may view the hard copy of the... to illustrate your concerns, and suggest alternatives. g. Explain your views as clearly as possible..., Maintenance Demonstration, Monitoring Network/Verification of Continued Attainment, Contingency Plan, and...

75 FR 27944 - Approval and Promulgation of Implementation Plans; Designation of Areas for Air Quality Planning...

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2010-05-19

... available only at the hard copy location (e.g., copyrighted material), and some may not be publicly available in either location (e.g., Confidential Business Information). To inspect the hard copy materials..., quality-assured and certified data gathered at established state and local air monitoring stations (SLAMS...

[Relationship between mitochondrial DNA copy number, membrane potential of human embryo and embryo morphology].

Science.gov (United States)

Zhao, H; Teng, X M; Li, Y F

2017-11-25

Objective: To explore the relationship between the embryo with the different morphological types in the third day and its mitochondrial copy number, the membrane potential. Methods: Totally 117 embryos with poor development after normal fertilization and were not suitable transferred in the fresh cycle and 106 frozen embryos that were discarded voluntarily by infertility patients with in vitro fertilization-embryo transfer after successful pregnancy were selected. According to evaluation of international standard in embryos, all cleavage stage embryos were divided into class Ⅰ frozen embryo group ( n= 64), class Ⅱ frozen embryo group ( n= 42) and class Ⅲ fresh embryonic group (not transplanted embryos; n= 117). Real-time PCR and confocal microscopy methods were used to detect mitochondrial DNA (mtDNA) copy number and the mitochondrial membrane potential of a single embryo. The differences between embryo quality and mtDNA copy number and membrane potential of each group were compared. Results: The copy number of mtDNA and the mitochondrial membrane potential in class Ⅲ fresh embryonic group [(1.7±1.0)×10(5) copy/μl, 1.56±0.32] were significantly lower than those in class Ⅰ frozen embryo group [(3.4±1.7)×10(5) copy/μl, 2.66±0.21] and class Ⅱ frozen embryo group [(2.6±1.2)×10(5) copy/μl, 1.80±0.32; all Pembryo group were significantly higher than those in classⅡ frozen embryo group (both Pembryos of the better quality embryo are higher.

Comportamiento dinámico de puentes en arco con amortiguadores viscosos

Directory of Open Access Journals (Sweden)

Nicolás Parra García

2007-11-01

Full Text Available En éste trabajo se presenta la respuesta sísmica analítica de dos puentes en arco de gran luz, sometiéndolos a un movimiento simulado que incluye efectos de fuente cercana. Para reducir la respuesta se exploró su comportamiento conectando los dos extremos del tablero con la subestructura por medio de amortiguadores viscosos. Se llevaron a cabo una serie de análisis en el plano de ambos modelos para identificar los amortiguadores óptimos. Los resultados indicaron que el uso de amortiguadores viscosos con comportamiento no lineal, ofrece una solución práctica para reducir la respuesta dinámica de estas estructuras.

La demanda de carnes y pescados en Túnez: un enfoque dinámico

OpenAIRE

Gil, José M.ª; Dhehibi, B.; Angulo, Ana Maria

2001-01-01

El objetivo de este trabajo consiste en analizar la demanda de carnes y pescado en Túnez utilizando sistemas econométricos multiecuacionales en base a datos de series temporales para el período 1973-1997. Se ha prestado especial atención a la especificación del modelo y al cumplimiento de las restricciones teóricas. Desde el primer punto de vista, se ha optado por un enfoque dinámico general que permite seleccionar la forma funcional que mejor se ajusta a los datos. Los resultados del análisi...

Dinámicas relacionales en familias con un miembro consumidor de sustancias psicoactivas

OpenAIRE

Noreña Orozco, Sandra Patricia

2017-01-01

La investigación tuvo como propósito analizar las dinámicas relacionales que caracterizan el sistema familiar, cuando uno de sus miembros es consumidor de sustancias psicoactivas (SPA). La metodología se orientó desde una perspectiva cualitativa, a través de un estudio de caso con un enfoque hermenéutico. Para ello se contó con cuatro familias en las que uno de sus miembros fuera consumidor de SPA, contando con la participación de nueve personas, entre ellos las personas que consumen. Se esta...

A Mobilização de Capacidades Dinâmicas na Lojas Renner

OpenAIRE

Adalberto Escalona Gonçalves Garcia; Luiz Paulo Bignetti

2014-01-01

O artigo tem como objetivo analisar a trajetória de uma das empresas varejistas de maior destaque no mercado brasileiro, através de um estudo longitudinal que enfatiza a mobilização de seus recursos e capacidades ao longo de 90 anos de história. Explorando o conceito de capacidades dinâmicas, descrevem-se as ações estratégicas empreendidas em momentos de crescimento e de crise. Para tanto, foram realizadas entrevistas em profundidade com dez tomadores de decisão que vivenciaram diferentes mom...

Din - Turizm İlişkisi Çerçevesinde Yahudilikte, Hıristiyanlıkta Ve İslamiyette Hac Uygulamasına Genel Bakış

Directory of Open Access Journals (Sweden)

Mehmet Alparslan Küçük

2013-06-01

Full Text Available Turizm sektörü, gerek dinî yaşam biçimi gerekse dinî kurumlar ile etkileşim ve iletişim halindedir. Bu etkileşim ve iletişim, dünyanın her yerinde görülebilmektedir. Turizm ile din arasındaki bu iletişim/etkileşim neticesinde inanç turizmi anlayışı ortaya çıkmıştır. İnanç Turizmi ile Hac arasında yakın bir ilişki sözkonusudur. Ancak Hac anlayışı ile inanç turizmi arasında ortak özellikler ile birlikte bazı farklılıklar da mevcuttur. Bu makalemizde bu benzerlikler ve farklılıklar ile birlikte Yahudilik, Hıristiyanlık ve İslamiyet’teki hac anlayışı/uygulaması ele alınmıştır

Influencia de la temperatura y nivel de energía de compactación en las propiedades dinámicas de una mezcla asfáltica

Directory of Open Access Journals (Sweden)

Óscar Javier Reyes Ortiz

2006-01-01

Full Text Available La temperatura de las mezclas asfálticas varía significativamente desde su producción en la planta hasta la conformación de la estructura de pavimento, especialmente en el proceso de compactación. Estas diferencias de temperatura de la mezcla de un punto a otro, generan segregación, microfisuras, superficies onduladas, desgarramientos y especialmente cambios en las propiedades mecánicas y dinámicas de la mezcla.En este estudio de laboratorio se determinó el efecto en el módulo dinámico, densidad, estabilidad y flujo de una mezcla asfáltica con granulometría 0/10 y asfalto con penetración 60/70, al variar la temperatura de compactación. Se establece que al compactar muestras entre 100 y 150 ºC existe descenso del orden de 30% en el módulo dinámico, 5% en la densidad y 50% en la estabilidad.

Ventilation components according to DIN 1946-6. Messages from the C.A.T.S. Academy; Lueftungskomponenten nach DIN 1946-6. Mitteilungen aus der C.A.T.S.-Academy

Energy Technology Data Exchange (ETDEWEB)

Nadler, Norbert [CSE Nadler, Oranienburg (Germany)

2011-07-01

On the one hand, the buildings are performed tightly according to the building regulations, on the other hand a minimum of air change is to be ensured. The former demand for air change by manual opening of the windows is no longer accepted. The calculation method of the regulation DIN 1946-6 enables both the establishment of a ventilation concept as well as an interpretation of the ventilation components. A critical evaluation of the regulation and the demands of practice result in necessary amendments which result in requirements of the appropriate software. The implementation of these requirements exemplary is demonstrated on the basis od the new C.A.T.S. ventilation.

Diseño de escenarios virtuales para problemas de optimización a través de geometría dinámica.

OpenAIRE

Freddy Yesid Villamizar Araque; Olga Lucy Rincón Leal; Mawency Vergel Ortega

2018-01-01

El presente artículo tiene el objetivo de analizar la influencia del uso de tecnologías digitales, particularmente, de software de geometría dinámica, acompañado de una didáctica en la concepción y solución de problemas aplicados, en un enfoque de enseñanza activa, en temas de optimización. La metodología siguió un enfoque cualitativo, se desarrolló a partir de taller con profesores, en el cual se resolvieron problemas en el contexto de máximos y mínimos de forma analítica y dinámica media...

Clasificación y detección de fallas en Sistemas Dinámicos

Directory of Open Access Journals (Sweden)

Javier Hernando Pardo Mayorga

2006-05-01

Full Text Available En los sistemas dinámicos se pueden presentar fallas en cualquier instante de tiempo, estas fallas pueden ser generadas en gran cantidad de casos por la variación de uno o más parámetros de la planta o del sistema dinámico. En este trabajo se propone la detección de fallas en una planta no lineal de dos tanques acoplados uno con área constante y otro variable con la altura esto basado en observadores adaptivos, sustentado con clasificación LAMDA y análisis de componentes principales. Se presenta la aplicación del algoritmo en un sistema no lineal, control del nivel en un sistema de tanques acoplados, así como el análisis de resultados conclusiones y perspectivas futuras./ In the dynamic systems a fail can occur in any moment, the fail can be present for variations in one or more parameter of the dynamic system. This paper present a fail detection in a non linear system compose by two tanks in parallel one with constant transversal area and the other one with variable area, the work is develop with adaptive observers and LAMDA classification. The application on this paper is in a non linear system, the level control in the two tank system.

Thermal spray coatings replace hard chrome

International Nuclear Information System (INIS)

Schroeder, M.; Unger, R.

1997-01-01

Hard chrome plating provides good wear and erosion resistance, as well as good corrosion protection and fine surface finishes. Until a few years ago, it could also be applied at a reasonable cost. However, because of the many environmental and financial sanctions that have been imposed on the process over the past several years, cost has been on a consistent upward trend, and is projected to continue to escalate. Therefore, it is very important to find a coating or a process that offers the same characteristics as hard chrome plating, but without the consequent risks. This article lists the benefits and limitations of hard chrome plating, and describes the performance of two thermal spray coatings (tungsten carbide and chromium carbide) that compared favorably with hard chrome plating in a series of tests. It also lists three criteria to determine whether plasma spray or hard chrome plating should be selected

Dinámica de los componentes demográficos en Baja California, durante el periodo 1985-1990

Directory of Open Access Journals (Sweden)

Gabriel Estrella Valenzuela

1991-09-01

Full Text Available En este trabajo se identifican los rangos predominantes en la dinámica de los componentes demográficos del estado de Baja California y sus municipios, durante el período 1985-1990. Para ello, se utilizan y combinan datos de estadísticas vitales, censales y de las Encuestas Demográficas de Baja California de 1986 y 1990. A partir del análisis de la mortalidad y la fecundidad, se logra determinar una tendencia de estabilidad en el componente natural de la dinámica demográfica del estado, con variaciones marginales a nivel municipal. En el rubro de crecimiento social, sin embargo, se observa un notable y claro incremento en la movilidad de la población que se sustenta en dos componentes: un incremento en la tasa de emigración desde el estado en su conjunto y una más elevada y consistente tendencia al incremento en las tasas de inmigración hacia Baja California, que revierte la tendencia decreciente del peso del crecimiento social en la entidad

Control de Robots Móviles con Incertidumbres Dinámicas usando Redes de Base Radial

Directory of Open Access Journals (Sweden)

Francisco G. Rossomando

2010-10-01

Full Text Available Resumen: En este trabajo se presenta un control de seguimiento de trayectorias de robots móviles. La estructura de control propuesta combina una linealización por realimentación basada en el modelo cinemático nominal, y una red neuronal directa para el control dinámico adaptable. La dinámica del robot es aprendida por una red neuronal basada en funciones de base radial (RN-FBR en un lazo de realimentación adaptable, ajustando el peso y las funciones de base radial. Se muestra un análisis de estabilidad del sistema de neuro-control adaptable. Se comprueba que los errores de control están limitados en función del error de aproximación de la RN-FBR. El funcionamiento del controlador también se verifica experimentalmente. Palabras clave: robot móvil, control no lineal, redes neuronales, control adaptable, funciones de base radial

Sobre a dinâmica da ideologia à luz da interpretação lukácsiana

Directory of Open Access Journals (Sweden)

Nara Roberta Silva

2015-06-01

Full Text Available Reconhecendo que o conceito de ideologia apresenta uma gama de significados, acepções e definições, o artigo procura debatê-lo dentro da leitura de György Lukács – considerando que não há uma concepção de ideologia sistematizada pelo próprio Karl Marx. Com isso, parte-se da relação não dicotômica entre realidade objetiva e subjetividade visualizada através do trabalho, cerne da teoria marxiana, e define-se ideologia a partir de sua função social de intervir nos conflitos, impasses, questões etc. de cunho também social. Em decorrência, considerando seu caráter de consciência eminentemente prática, exploram-se então aspectos concernentes à complexa dinâmica da ideologia, que possibilitam compreender sua atuação e sua influência em meio a uma dada formação social – dinâmica esta sintetizada no que optamos por chamar de linguagem da evidência.

Processos globais e mercado de trabalho: novas dinâmicas no setor automotivo no Brasil - anos 2000

Directory of Open Access Journals (Sweden)

Garcia, Sandro Ruduit

2007-01-01

Full Text Available O artigo tenta identificar novas dinâmicas no mercado de trabalho, face aos processos globais, a partir do que vem ocorrendo no setor automotivo brasileiro nos anos 2000, focando particularmente o caso do pólo de Gravataí (RS. O argumento central da análise é de que a constituição de processos globais promove novas dinâmicas em mercados de trabalho regionais. A abertura de mercados de produtos, as composições entre capitais nacionais e estrangeiros e os investimentos em novas plantas industriais expressam processos globais que poderiam criar novas atividades e funções produtivas, empresas e empregos, assim como estimular capacidades e conhecimentos. Por outro lado, a competitividade, instabilidade e interdependência do sistema global reforçariam a seletividade social nos mercados de trabalho regionais, constituindo novos riscos e ansiedades para segmentos econômicos e sociais vulneráveis. Isso tenderia a mobilizar instituições no esforço de tentar reparar distorções face à nova complexidade do mercado de trabalho

Accurate measure of transgene copy number in crop plants using droplet digital PCR

Science.gov (United States)

Genetic transformation is a powerful means for the improvement of crop plants, but requires labor- and resource-intensive methods. An efficient method for identifying single-copy transgene insertion events from a population of independent transgenic lines is desirable. Currently, transgene copy numb...

Investigation of Copy Number Variation in Children with Conotruncal Heart Defects

International Nuclear Information System (INIS)

Campos, Carla Marques Rondon; Zanardo, Evelin Aline; Dutra, Roberta Lelis; Kulikowski, Leslie Domenici; Kim, Chong Ae

2015-01-01

Congenital heart defects (CHD) are the most prevalent group of structural abnormalities at birth and one of the main causes of infant morbidity and mortality. Studies have shown a contribution of the copy number variation in the genesis of cardiac malformations. Investigate gene copy number variation (CNV) in children with conotruncal heart defect. Multiplex ligation-dependent probe amplification (MLPA) was performed in 39 patients with conotruncal heart defect. Clinical and laboratory assessments were conducted in all patients. The parents of the probands who presented abnormal findings were also investigated. Gene copy number variation was detected in 7/39 patients: 22q11.2 deletion, 22q11.2 duplication, 15q11.2 duplication, 20p12.2 duplication, 19p deletion, 15q and 8p23.2 duplication with 10p12.31 duplication. The clinical characteristics were consistent with those reported in the literature associated with the encountered microdeletion/microduplication. None of these changes was inherited from the parents. Our results demonstrate that the technique of MLPA is useful in the investigation of microdeletions and microduplications in conotruncal congenital heart defects. Early diagnosis of the copy number variation in patients with congenital heart defect assists in the prevention of morbidity and decreased mortality in these patients

Investigation of Copy Number Variation in Children with Conotruncal Heart Defects

Energy Technology Data Exchange (ETDEWEB)

Campos, Carla Marques Rondon, E-mail: carlamcampos@uol.com.br [Universidade Federal de Mato Grosso, Cuiabá, MT (Brazil); Zanardo, Evelin Aline; Dutra, Roberta Lelis [Departamento de Patologia - Laboratório de Citogenômica - LIM 03 - Universidade de São Paulo, São Paulo, SP (Brazil); Kulikowski, Leslie Domenici [Universidade de São Paulo, São Paulo, SP (Brazil); Departamento de Patologia - Laboratório de Citogenômica - LIM 03 - Universidade de São Paulo, São Paulo, SP (Brazil); Kim, Chong Ae [Universidade de São Paulo, São Paulo, SP (Brazil)

2015-01-15

Congenital heart defects (CHD) are the most prevalent group of structural abnormalities at birth and one of the main causes of infant morbidity and mortality. Studies have shown a contribution of the copy number variation in the genesis of cardiac malformations. Investigate gene copy number variation (CNV) in children with conotruncal heart defect. Multiplex ligation-dependent probe amplification (MLPA) was performed in 39 patients with conotruncal heart defect. Clinical and laboratory assessments were conducted in all patients. The parents of the probands who presented abnormal findings were also investigated. Gene copy number variation was detected in 7/39 patients: 22q11.2 deletion, 22q11.2 duplication, 15q11.2 duplication, 20p12.2 duplication, 19p deletion, 15q and 8p23.2 duplication with 10p12.31 duplication. The clinical characteristics were consistent with those reported in the literature associated with the encountered microdeletion/microduplication. None of these changes was inherited from the parents. Our results demonstrate that the technique of MLPA is useful in the investigation of microdeletions and microduplications in conotruncal congenital heart defects. Early diagnosis of the copy number variation in patients with congenital heart defect assists in the prevention of morbidity and decreased mortality in these patients.

Structure, production and properties of high-melting compounds and systems (hard materials and hard metals)

International Nuclear Information System (INIS)

Holleck, H.; Thuemmler, F.

1979-07-01

The report contains contributions by various authors to the research project on the production, structure, and physical properties of high-melting compounds and systems (hard metals and hard materials), in particular WC-, TaC-, and MoC-base materials. (GSCH) [de

Copy-number analysis and inference of subclonal populations in cancer genomes using Sclust.

Science.gov (United States)

Cun, Yupeng; Yang, Tsun-Po; Achter, Viktor; Lang, Ulrich; Peifer, Martin

2018-06-01

The genomes of cancer cells constantly change during pathogenesis. This evolutionary process can lead to the emergence of drug-resistant mutations in subclonal populations, which can hinder therapeutic intervention in patients. Data derived from massively parallel sequencing can be used to infer these subclonal populations using tumor-specific point mutations. The accurate determination of copy-number changes and tumor impurity is necessary to reliably infer subclonal populations by mutational clustering. This protocol describes how to use Sclust, a copy-number analysis method with a recently developed mutational clustering approach. In a series of simulations and comparisons with alternative methods, we have previously shown that Sclust accurately determines copy-number states and subclonal populations. Performance tests show that the method is computationally efficient, with copy-number analysis and mutational clustering taking Linux/Unix command-line syntax should be able to carry out analyses of subclonal populations.

Gauged Supergravities and Spontaneous Supersymmetry Breaking from the Double Copy Construction

Science.gov (United States)

Chiodaroli, M.; Günaydin, M.; Johansson, H.; Roiban, R.

2018-04-01

Supergravities with gauged R symmetry and Minkowski vacua allow for spontaneous supersymmetry breaking and, as such, provide a framework for building supergravity models of phenomenological relevance. In this Letter, we initiate the study of double copy constructions for these supergravities. We argue that, on general grounds, we expect their scattering amplitudes to be described by a double copy of the type (spontaneously broken gauge theory)⊗ (gauge theory with broken supersymmetry). We present a simple realization in which the resulting supergravity has U (1 )R gauge symmetry, spontaneously broken N =2 supersymmetry, and massive gravitini. This is the first instance of a double copy construction of a gauged supergravity and of a theory with spontaneously broken supersymmetry. The construction extends in a straightforward manner to a large family of gauged Yang-Mills-Einstein supergravity theories with or without spontaneous gauge-symmetry breaking.

Community helping services: dynamic of formation and expressiveness of the cultural care Comunidad mutirante: dinâmica de formación y expresividad del cuidado cultural Comunidade mutirante: dinâmica de formação e expressividade do cuidado cultural

Directory of Open Access Journals (Sweden)

Fátima Luna Pinheiro Landim

2006-12-01

Full Text Available Community helping services is an expression used by the social movements to designate families that live in shacks installed in a public area intended for building of own house at a community helping system. Studies in ethnonursing that aimed: in order to detail dynamic configuration in a community helping service. It took place in an community helping area located in the outskirts of Fortaleza, Ceará. The community members acting as general informants from the local culture, while eight (8 women heads-of-families, working as key informers. The data collect used the Observation-Participation-Reflection Model. The analyses were processing by the time that the dates were collected, considering the categories: inserting in the community helping culture to obtain their history; community helping is not a slum -describing the formation dynamic. Established that the formation dynamic of the community helping go on the own house representation as a symbol of " a better life". To assimilate such expression introducing in own cultural universe is a challenge for the nursing to assist a care culture congruent.Comunidad "mutirante" es una expresión utilizada por los movimientos sociales para designar familias que habitan barracas instaladas en terreno público destinado a la construción comunitaria de las casas que esas familias habitarán. Estudio en etnoenfermagem, que tuvo como objetivo: describir la dinámica de formación de una comunidad mutirante. Fue realizado en un área de construcción comunitaria localizada en la periferia de Fortaleza-Ceará-Brasil. Los miembros de la comunidad actuaron como informantes generales de la cultura local, mientras que ocho mujeres jefes de familia fueron informantes llave. La colecta de datos utilizó el modelo de Observación-Participación-Refleja. Los análises fueron siendo procesados al mismo tiempo en que los datos fueron colectados, considerando las categorías: Insertándose en la cultura mutirante para

Los modelos de organización y dinámicas espaciales metropolitanas en Andalucía

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José Mª Feria Toribio

2015-01-01

Full Text Available Este artículo aborda dos dimensiones relevantes de la nueva configuración de la ciudad en Andalucía.Al igual que en todos los países de su entorno, esta nueva configuración es metropolitanatanto en el plano formal como en el funcional, lo que significa que supera nítidamente los límitesfísicos y administrativos de la ciudad tradicional, para abarcar territorios y redes de asentamientoscada vez más amplios. En ese sentido, aquí se centrará el análisis, en primer lugar, en el modoy disposición en el que se organizan espacialmente los diferentes componentes de la ciudad metropolitanay, en segundo lugar, en cuáles son las dinámicas de dicha ciudad tanto en su conjuntocomo en sus componentes. La diversidad y complejidad del sistema metropolitano andaluz, connueve áreas metropolitanas de diferente nivel jerárquico, permite además que este análisis nopersiga sólo caracterizar este universo urbano sino que también sirva para establecer modelos deorganización y dinámicas extensibles a cualquier otro sistema metropolitano.

DInSAR-Based Detection of Land Subsidence and Correlation with Groundwater Depletion in Konya Plain, Turkey

Directory of Open Access Journals (Sweden)

Fabiana Caló

2017-01-01

Full Text Available In areas where groundwater overexploitation occurs, land subsidence triggered by aquifer compaction is observed, resulting in high socio-economic impacts for the affected communities. In this paper, we focus on the Konya region, one of the leading economic centers in the agricultural and industrial sectors in Turkey. We present a multi-source data approach aimed at investigating the complex and fragile environment of this area which is heavily affected by groundwater drawdown and ground subsidence. In particular, in order to analyze the spatial and temporal pattern of the subsidence process we use the Small BAseline Subset DInSAR technique to process two datasets of ENVISAT SAR images spanning the 2002–2010 period. The produced ground deformation maps and associated time-series allow us to detect a wide land subsidence extending for about 1200 km2 and measure vertical displacements reaching up to 10 cm in the observed time interval. DInSAR results, complemented with climatic, stratigraphic and piezometric data as well as with land-cover changes information, allow us to give more insights on the impact of climate changes and human activities on groundwater resources depletion and land subsidence.

rRNA Operon Copy Number Can Explain the Distinct Epidemiology of Hospital-Associated Methicillin-Resistant Staphylococcus aureus

Science.gov (United States)

Jansen, M. D.; Bosch, T.; Jansen, W. T. M.; Schouls, L.; Jonker, M. J.; Boel, C. H. E.

2016-01-01

The distinct epidemiology of original hospital-associated methicillin-resistant Staphylococcus aureus (HA-MRSA) and early community-associated MRSA (CA-MRSA) is largely unexplained. S. aureus carries either five or six rRNA operon copies. Evidence is provided for a scenario in which MRSA has adapted to the hospital environment by rRNA operon loss (six to five copies) due to antibiotic pressure. Early CA-MRSA, in contrast, results from wild-type methicillin-susceptible S. aureus (MSSA) that acquired mecA without loss of an rRNA operon. Of the HA-MRSA isolates (n = 77), 67.5% had five rRNA operon copies, compared to 23.2% of the CA-MRSA isolates (n = 69) and 7.7% of MSSA isolates (n = 195) (P operon copies. For all subsets, a correlation between resistance profile and rRNA copy number was found. Furthermore, we showed that in vitro antibiotic pressure may result in rRNA operon copy loss. We also showed that without antibiotic pressure, S. aureus isolates containing six rRNA copies are more fit than isolates with five copies. We conclude that HA-MRSA and cystic fibrosis isolates most likely have adapted to an environment with high antibiotic pressure by the loss of an rRNA operon copy. This loss has facilitated resistance development, which promoted survival in these niches. However, strain fitness decreased, which explains their lack of success in the community. In contrast, CA-MRSA isolates retained six rRNA operon copies, rendering them fitter and thereby able to survive and spread in the community. PMID:27671073

78 FR 72608 - Approval and Promulgation of Implementation Plans; State of Missouri

Science.gov (United States)

2013-12-03

..., such as copyrighted material, will be publicly available only in hard copy. Publicly available docket materials are available either electronically in www.regulations.gov or in hard copy at the Environmental... consistent with the state's standard rule format or make other minor clarifying changes. Subparagraphs 3(B)3...

21 CFR 1304.04 - Maintenance of records and inventories.

Science.gov (United States)

2010-04-01

... name, patient's name, drug dispensed, and date filled, then the requirement to mark the hard copy... prescriber name, patient's name, drug dispensed, and date filled, then the requirement to mark the hard copy... format that is readily understandable to an Administration or other law enforcement agent at the...

76 FR 34233 - Privacy Act of 1974; U.S. Citizenship and Immigration Services, Immigration and Customs...

Science.gov (United States)

2011-06-13

... formatting and text of the previously published notice and improve the public's understanding of the system... security. Hard copies of the A-Files are primarily located at the records centers in Lee Summit, Missouri; Suitland, Maryland; San Bruno, California; Seattle, Washington; and Dayton, Ohio. Hard copies may also be...

75 FR 48329 - Tribal Drinking Water Operator Certification Program

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2010-08-10

... operator has the skills, knowledge, education and experience necessary to deliver safe water supporting... demonstrates the operator has the skills, knowledge, education and experience necessary to deliver safe water... this program can be found at http://www.epa.gov/safewater/tribal.html . 2. Hard Copies. Hard copies of...

77 FR 38866 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing...

Science.gov (United States)

2012-06-29

... is made for either an individual or member, FINRA must, among other things, confirm that the matter... via a hard copy fingerprint card. FINRA is proposing to increase the processing fee for fingerprints submitted electronically to $15 and to increase the fee for fingerprints submitted by a hard copy...

78 FR 2210 - Review of New Sources and Modifications in Indian Country: Notice of Action Partially Granting...

Science.gov (United States)

2013-01-10

..., the Petitioners). In the letter dated August 30, 2011, the Petitioners asked, among other things, that... and will be publicly available only in hard copy form. Publicly available docket materials are available electronically through http://www.regulations.gov or in hard copy at the EPA Docket Center, Docket...

77 FR 70776 - Draft Integrated Science Assessment for Lead

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2012-11-27

... certain pollutants which, among other things, ``cause or contribute to air pollution, which may reasonably... available only in hard copy. Publicly available docket materials are available either electronically in www.regulations.gov or in hard copy at the OEI Docket in the EPA Headquarters Docket Center. Dated: September 28...

75 FR 80496 - Registration Review; Pesticide Dockets Opened for Review and Comment and Other Docket Actions

Science.gov (United States)

2010-12-22

... in hard copy form. Publicly available docket materials are available either in the electronic docket at http://www.regulations.gov , or, if only available in hard copy, at the OPP Regulatory Public... 155, subpart C. Section 3(g) of FIFRA provides, among other things, that the registrations of...

76 FR 48002 - Approval and Promulgation of Air Quality Implementation Plans; State of California; Interstate...

Science.gov (United States)

2011-08-08

... things, adequate measures prohibiting emissions of air pollutants in amounts which will interfere with...://www.regulations.gov and in hard copy at EPA Region IX, 75 Hawthorne Street, San Francisco, California... only at the hard copy location (e.g., copyrighted material) and some may not be available in either...

76 FR 38166 - Registration Review; Pesticide Dockets Opened for Review and Comment and Other Docket Actions

Science.gov (United States)

2011-06-29

... in hard copy form. Publicly available docket materials are available either in the electronic docket at http://www.regulations.gov , or, if only available in hard copy, at the OPP Regulatory Public.... Section 3(g) of FIFRA provides, among other things, that the registrations of pesticides are to be...

75 FR 38521 - Registration Review; Biopesticide Dockets Opened for Review and Comment

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2010-07-02

... in hard copy form. Publicly available docket materials are available either in the electronic docket at http://www.regulations.gov , or, if only available in hard copy, at the OPP Regulatory Public.... Section 3(g) of FIFRA provides, among other things, that the registrations of pesticides are to be...

75 FR 29534 - Inorganic Nitrates-Nitrite, Carbon and Carbon Dioxide, and Sulfur Registration Review; Draft...

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2010-05-26

..., among other things, the Agency's risk assessment methodologies and assumptions, as applied to this draft... and will be publicly available only in hard copy form. Publicly available docket materials are available either in the electronic docket at http://www.regulations.gov , or, if only available in hard copy...

75 FR 60119 - Registration Review; Antimicrobial Pesticide Dockets Opened for Review and Comment

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2010-09-29

... and will be publicly available only in hard copy form. Publicly available docket materials are available either in the electronic docket at http://www.regulations.gov , or, if only available in hard copy... 155, subpart C. Section 3(g) of FIFRA provides, among other things, that the registrations of...

78 FR 54813 - Approval and Promulgation of Air Quality Implementation Plans; Colorado; Construction Permit...

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2013-09-06

... to Regulation 3, Part A, Section VI.D.1., in which the State, among other things, increased the... material, will be publicly available only in hard copy. Publicly available docket materials are available either electronically in www.regulations.gov or in hard copy at the Air Program, Environmental Protection...

76 FR 11983 - Approval and Promulgation of Air Quality Implementation Plans; Pennsylvania; Adoption of Control...

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2011-03-04

... publicly available only in hard copy form. Publicly available docket materials are available either electronically in http://www.regulations.gov or in hard copy during normal business hours at the Air Protection..., EPA, among other things, evaluated the sources of VOC emissions from this industry and the available...

75 FR 66757 - Stakeholder Input; Listening Session Seeking Suggestions for Improving the Next National...

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2010-10-29

..., will be publicly available only in hard copy. Publicly available docket materials are available either electronically in http://www.regulations.gov or in hard copy at the Water Docket, EPA/ DC, EPA West, Room 3334... discharge. For each discharge type, among other things, the 2008 permit establishes effluent limits...

75 FR 53613 - Notice of Data Availability Supporting Federal Implementation Plans To Reduce Interstate...

Science.gov (United States)

2010-09-01

... information relevant to the rulemaking, including, among other things, an updated version of the power sector..., such as copyrighted material, will be publicly available only in hard copy. Publicly available docket materials are available either electronically in http://www.regulations.gov or in hard copy at the Air and...

76 FR 13567 - Approval and Promulgation of Air Quality Implementation Plans; Pennsylvania; Adoption of Control...

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2011-03-14

... publicly available only in hard copy form. Publicly available docket materials are available either electronically in http://www.regulations.gov or in hard copy during normal business hours at the Air Protection..., EPA, among other things, evaluated the sources of VOC emissions from this industry and the available...

78 FR 71550 - Approval and Promulgation of Air Quality Implementation Plans; State of Colorado Second Ten-Year...

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2013-11-29

... INFORMATION CONTACT section to view the hard copy of the docket. You may view the hard copy of the docket... your concerns, and suggest alternatives. g. Explain your views as clearly as possible, avoiding the use..., Contingency Plan, and Transportation Conformity Requirements including the Motor Vehicle Emission Budget for...

75 FR 13710 - Approval and Promulgation of Implementation Plans; Designation of Areas for Air Quality Planning...

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2010-03-23

... only at the hard copy location (e.g., copyrighted material), and some may not be publicly available in either location (e.g., CBI). To inspect the hard copy materials, please schedule an appointment during... at established state and local air monitoring stations (SLAMS) in the nonattainment area and entered...

[Quality assurance in student training. Prerequisites for DIN EN ISO 9001:2000 in teaching].

Science.gov (United States)

Ochsner, W; Kaiser, C; Schirmer, U

2007-07-01

Standards of quality assurance according to DIN EN ISO 9001:2000 have been implemented in many university hospital departments, but often teaching activities are not included. This work presents a method that allows, after having defined the various teaching activities as sub-processes of one single core process, to include the manifold teaching activities of university hospital departments into the certification process. The stepwise description of the prerequisites for including teaching activities into ISO 9001 certification is illustrated by a concrete implementation example.

Dinámica demográfica y generación de viajes al trabajo en el AMCM: 1994-2000

Directory of Open Access Journals (Sweden)

Boris Graizbord

2005-01-01

Full Text Available Entre la vasta gama de problemas urbanos que afectan a la Ciudad de México es de vital importancia el transporte pues implica la movilidad de la población. Los diversos modos de transporte, públicos y privados, permiten acceder a los mercados urbanos, principalmente al de trabajo y al de vivienda, pero también a los mercados de bienes y servicios. Sin embargo, no se ha llevado a cabo un análisis a fondo de tales fenómenos conforme lo exigen los problemas, y a nuestro entender esto obedece a dos razones fundamentales: 1 la incipiente generación y escasa disponibilidad de datos que permitananalizar la estructura del transporte, y 2 la carencia de los elementos conceptuales necesarios para vincular el transporte con la dinámica de crecimiento de la metrópoli ycon el proceso de planificación de la ciudad. En este trabajo pretendemos avanzar en el análisis de la dinámica del transporte urbano de pasajeros en el Área Metropolitana de la Ciudad de México (AMCM. Lo haremos resaltando las diferencias absolutas y relativas en la generación de viajes rumbo al trabajo en dos momentos en el tiempo: 1994 y 2000. Esto nos brinda la posibilidad de acercarnos a una mayor comprensión de la dinámica de dos fenómenos,la ciudad y el transporte, y de apreciar así algunas relaciones entre ambos.

Beta-defensin genomic copy number is not a modifier locus for cystic fibrosis

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Burgess Juliana

2005-12-01

Full Text Available Abstract Human beta-defensin 2 (DEFB4, also known as DEFB2 or hBD-2 is a salt-sensitive antimicrobial protein that is expressed in lung epithelia. Previous work has shown that it is encoded in a cluster of beta-defensin genes at 8p23.1, which varies in copy number between 2 and 12 in different individuals. We determined the copy number of this locus in 355 patients with cystic fibrosis (CF, and tested for correlation between beta-defensin cluster genomic copy number and lung disease associated with CF. No significant association was found.

Hard-hard coupling assisted anomalous magnetoresistance effect in amine-ended single-molecule magnetic junction

Science.gov (United States)

Tang, Y.-H.; Lin, C.-J.; Chiang, K.-R.

2017-06-01

We proposed a single-molecule magnetic junction (SMMJ), composed of a dissociated amine-ended benzene sandwiched between two Co tip-like nanowires. To better simulate the break junction technique for real SMMJs, the first-principles calculation associated with the hard-hard coupling between a amine-linker and Co tip-atom is carried out for SMMJs with mechanical strain and under an external bias. We predict an anomalous magnetoresistance (MR) effect, including strain-induced sign reversal and bias-induced enhancement of the MR value, which is in sharp contrast to the normal MR effect in conventional magnetic tunnel junctions. The underlying mechanism is the interplay between four spin-polarized currents in parallel and anti-parallel magnetic configurations, originated from the pronounced spin-up transmission feature in the parallel case and spiky transmission peaks in other three spin-polarized channels. These intriguing findings may open a new arena in which magnetotransport and hard-hard coupling are closely coupled in SMMJs and can be dually controlled either via mechanical strain or by an external bias.

Melting of polydisperse hard disks

NARCIS (Netherlands)

Pronk, S.; Frenkel, D.

2004-01-01

The melting of a polydisperse hard-disk system is investigated by Monte Carlo simulations in the semigrand canonical ensemble. This is done in the context of possible continuous melting by a dislocation-unbinding mechanism, as an extension of the two-dimensional hard-disk melting problem. We find

FACULTĂȚILE DE LA UNIVERSITATEA DIN CERNĂUȚI (1875-1919

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Constantin UNGUREANU

2017-08-01

Full Text Available În perioada 1875-1919, Universitatea din Cernăuţi a funcţionat cu trei facultăţi: teologie ortodoxă, drept şi filozofie. Un rol aparte în cadrul Universităţii l-a îndeplinit Facultatea de Teologie Ortodoxă. La această facultate au activat 15 pro­fesori titulari, dintre care 13 români şi doi ucraineni. Facultatea de Drept a fost cea mai bine frecventată. Facultatea de Filozofie din Cernăuţi a cuprins mai multe secţii: filozofie, istorie, filologie şi lingvistică, matematică şi ştiinţe naturale, limbi moderne, fizică, chimie. În ajunul războiului, la această facultate activau 28 de catedre, dintre care 16 în domeniul ştiinţelor filologice şi istorice şi 12 în domeniul ştiinţelor naturale.FACULTIES AT THE UNIVERSITY OF CHERNIVTSI (1875-1919During 1875-1919,ChernivtsiUniversitywas comprised of three faculties: orthodox theology, law and philosophy. The Faculty of Orthodox Theology played a special role within the University. This department was comprised of 15 full professors, of which 13 were Romanian and 2 Ukrainians. Faculty of Law was the best frequented. The Faculty of Philosophy in Chernivtsi was comprised of several departments such as philosophy, history, philology and linguistics, mathematics and natural sciences, modern languages, physics and chemistry. Just before the Great War, this Faculty was comprised of 28 departments of which 16 were specialized in philology and history while 12 were specialized in the natural sciences.

Low AMY1 Gene Copy Number Is Associated with Increased Body Mass Index in Prepubertal Boys.

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M Loredana Marcovecchio

Full Text Available Genome-wide association studies have identified more than 60 single nucleotide polymorphisms associated with Body Mass Index (BMI. Additional genetic variants, such as copy number variations (CNV, have also been investigated in relation to BMI. Recently, the highly polymorphic CNV in the salivary amylase (AMY1 gene, encoding an enzyme implicated in the first step of starch digestion, has been associated with obesity in adults and children. We assessed the potential association between AMY1 copy number and a wide range of BMI in a population of Italian school-children.744 children (354 boys, 390 girls, mean age (±SD: 8.4±1.4years underwent anthropometric assessments (height, weight and collection of saliva samples for DNA extraction. AMY1 copies were evaluated by quantitative PCR.A significant increase of BMI z-score by decreasing AMY1 copy number was observed in boys (β: -0.117, p = 0.033, but not in girls. Similarly, waist circumference (β: -0.155, p = 0.003, adjusted for age was negatively influenced by AMY1 copy number in boys. Boys with 8 or more AMY1 copy numbers presented a significant lower BMI z-score (p = 0.04 and waist circumference (p = 0.01 when compared to boys with less than 8 copy numbers.In this pediatric-only, population-based study, a lower AMY1 copy number emerged to be associated with increased BMI in boys. These data confirm previous findings from adult studies and support a potential role of a higher copy number of the salivary AMY1 gene in protecting from excess weight gain.

27 CFR 478.95 - Certified copy of license.

Science.gov (United States)

2010-04-01

... for copies. The fee may be paid by (a) cash, or (b) money order or check made payable to the Bureau of Alcohol, Tobacco, Firearms, and Explosives. (Approved by the Office of Management and Budget under control...

Multiple-copy state discrimination: Thinking globally, acting locally

International Nuclear Information System (INIS)

Higgins, B. L.; Pryde, G. J.; Wiseman, H. M.; Doherty, A. C.; Bartlett, S. D.

2011-01-01

We theoretically investigate schemes to discriminate between two nonorthogonal quantum states given multiple copies. We consider a number of state discrimination schemes as applied to nonorthogonal, mixed states of a qubit. In particular, we examine the difference that local and global optimization of local measurements makes to the probability of obtaining an erroneous result, in the regime of finite numbers of copies N, and in the asymptotic limit as N→∞. Five schemes are considered: optimal collective measurements over all copies, locally optimal local measurements in a fixed single-qubit measurement basis, globally optimal fixed local measurements, locally optimal adaptive local measurements, and globally optimal adaptive local measurements. Here an adaptive measurement is one in which the measurement basis can depend on prior measurement results. For each of these measurement schemes we determine the probability of error (for finite N) and the scaling of this error in the asymptotic limit. In the asymptotic limit, it is known analytically (and we verify numerically) that adaptive schemes have no advantage over the optimal fixed local scheme. Here we show moreover that, in this limit, the most naive scheme (locally optimal fixed local measurements) is as good as any noncollective scheme except for states with less than 2% mixture. For finite N, however, the most sophisticated local scheme (globally optimal adaptive local measurements) is better than any other noncollective scheme for any degree of mixture.

Non-Abelian fractional quantum Hall states for hard-core bosons in one dimension

Science.gov (United States)

Paredes, Belén

2012-05-01

I present a family of one-dimensional bosonic liquids analogous to non-Abelian fractional quantum Hall states. A new quantum number is introduced to characterize these liquids, the chiral momentum, which differs from the usual angular or linear momentum in one dimension. As their two-dimensional counterparts, these liquids minimize a k-body hard-core interaction with the minimum total chiral momentum. They exhibit global order, with a hidden organization of the particles in k identical copies of a one-dimensional Laughlin state. For k=2 the state is a p-wave paired phase corresponding to the Pfaffian quantum Hall state. By imposing conservation of the total chiral momentum, an exact parent Hamiltonian is derived which involves long-range tunneling and interaction processes with an amplitude decaying with the chord distance. This family of non-Abelian liquids is shown to be in formal correspondence with a family of spin-(k)/(2) liquids which are total singlets made out of k indistinguishable resonating valence bond states. The corresponding spin Hamiltonians are obtained.

Cognitive profile of patients with rotated drawing at copy or recall: a controlled group study.

Science.gov (United States)

Molteni, Federica; Traficante, Debora; Ferri, Francesca; Isella, Valeria

2014-03-01

When copying or recalling a figure from memory, some patient with dementia or focal brain lesions may rotate the drawing through ±90° or 180°. We have tried to clarify the nature of this phenomenon by investigating the cognitive profile of 22 patients who rotated the copy of the Rey-Osterrieth Complex Figure and 27 who rotated (only) the recall, and two control groups of cases with the same neuropsychiatric diagnoses, but no misorientation deficit. Brain MRI and FDG-PET images were also analysed. Predictor of rotation at the copy versus rotation at the recall was visuospatial impairment as measured by the copy of the Rey Figure; predictors of rotation at the copy versus no rotation were, again, visuospatial deficits, in addition to an abnormal performance at the task of selective attention. No specific profile of cognitive impairment distinguished patients with and without rotation at the recall. Disproportionate temporo-parieto-occipital atrophy or hypometabolism were evident in cases with misorientation of the copy, while predominant frontal abnormalities were found in cases of rotated recall. Based on these findings, rotated drawing at the copy is interpreted as a dorsal visual stream deficit, whose occurrence is more probable when attentional control is impaired. Rotation at recall seems to have a distinct, more anterior, neural substrate, but its dysexecutive nature has yet to be demonstrated. Copyright © 2014 Elsevier Inc. All rights reserved.

Fatigue of DIN 1.4914 martensitic stainless steel in a hydrogen environment

Science.gov (United States)

Shakib, J. I.; Ullmaier, H.; Little, E. A.; Faulkner, R. G.; Schmilz, W.; Chung, T. E.

1994-09-01

Fatigue tests at room temperature in vacuum, air and hydrogen have been carried out on specimens of DIN 1.4914 martensitic stainless steel in load-controlled, push-pull type experiments. Fatigue lifetimes in hydrogen are significantly lower than in both vacuum and air and the degradation is enhanced by lowering the test frequency or introducing hold times into the tension half-cycle. Fractographic examinations reveal hydrogen embrittlement effects in the form of internal cracking between fatigue striations together with surface modifications, particularly at low stress amplitudes. It is suggested that gaseous hydrogen can influence both fatigue crack initiation and propagation events in martensitic steels.

Software para la enseñanza de la dinámica y control de intercambiadores de calor de tubos y coraza

Directory of Open Access Journals (Sweden)

Fiderman Machuca

2008-01-01

Full Text Available Este trabajo presenta la estructura de un software desarrollado para la enseñanza y aprendizaje de la dinámica y control de intercambiadores de calor de tubos y coraza. El programa presenta, de manera numérica y gráfica, el comportamiento dinámico en lazo abierto y cerrado del proceso para diferentes parámetros de diseño y condiciones de operación variables. El software permite modificar condiciones tanto de operación como de diseño, por ejemplo, temperatura y caudales de entrada a los tubos y coraza, número y longitud de tubos, número de pasos, diámetro externo e interno de los tubos, diámetro interno de coraza y factor de ensuciamiento.

78 FR 69793 - Voluntary Remedial Actions and Guidelines for Voluntary Recall Notices

Science.gov (United States)

2013-11-21

...'' and ``hard copy'' as possible forms of direct voluntary recall notice. Because firms often lack... formatting of a voluntary recall notice in the form of a press release should comport with the most current... transmitted using an electronic medium and in hard copy form. Acceptable forms of, and means for...

78 FR 75253 - Approval and Promulgation of Implementation Plans; New Mexico; Prevention of Significant...

Science.gov (United States)

2013-12-11

.... Certain other material, such as copyrighted material, will be publicly available only in hard copy... hard copy at the Air Permits Section (6PD-R), Please schedule an appointment with the person listed in... (5) NMAC to correct formatting, and Substantive revisions to 20.2.74.320 NMAC establishing the GHG...

77 FR 18810 - Registration Review; Pesticide Dockets Opened for Review and Comment and Other Docket Act

Science.gov (United States)

2012-03-28

... and will be publicly available only in hard copy form. Publicly available docket materials are available either in the electronic docket at http://www.regulations.gov , or, if only available in hard copy.... Section 3(g) of FIFRA provides, among other things, that the registrations of pesticides are to be...

75 FR 60117 - Registration Review; Biopesticides Dockets Opened for Review and Comment

Science.gov (United States)

2010-09-29

... publicly available only in hard copy form. Publicly available docket materials are available either in the electronic docket at http://www.regulations.gov , or, if only available in hard copy, at the OPP Regulatory.... Section 3(g) of FIFRA provides, among other things, that the registrations of pesticides are to be...

76 FR 11963 - Updating Cross-References for the Oklahoma State Implementation Plan

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2011-03-04

... material, such as copyrighted material, will be publicly available only in hard copy. Publicly available docket materials are available either electronically in http://www.regulations.gov or in hard copy at the... (CAA), among other things, further provides that CAA subsection 307(d) does not apply when EPA has made...

77 FR 65521 - Determination of Attainment for the San Francisco Bay Area Nonattainment Area for the 2006 Fine...

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2012-10-29

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77 FR 65646 - Determination of Attainment for the Yuba City-Marysville Nonattainment Area for the 2006 Fine...

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2012-10-30

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78 FR 41901 - Determination of Attainment for the West Central Pinal Nonattainment Area for the 2006 Fine...

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2013-07-12

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Advances in hard nucleus cataract surgery

Directory of Open Access Journals (Sweden)

Wei Cui

2013-11-01

Full Text Available Security and perfect vision and fewer complications are our goals in cataract surgery, and hard-nucleus cataract surgery is always a difficulty one. Many new studies indicate that micro-incision phacoemulsification in treating hard nucleus cataract is obviously effective. This article reviews the evolution process of hard nuclear cataract surgery, the new progress in the research of artificial intraocular lens for microincision, and analyse advantages and disadvantages of various surgical methods.

Perspectiva de Trazabilidad en la Cadena de Suministros de Frutas: Un Enfoque desde la Dinámica de SistemasPerspective of Traceability in the Food Supply Chain: An Approach from System Dynamics

Directory of Open Access Journals (Sweden)

Javier Arturo Orjuela Castro

2014-08-01

Full Text Available El presente artículo muestra un modelo causal, desarrollado a dos niveles, uno general basado en el comportamiento dinámico de la cadena de suministro de frutas, y otro específico para la implementación de tecnologías de trazabilidad en la cadena. Surge de la necesidad de identificar la dinámica de la implementación de tecnologías de trazabilidad en la cadena de frutas. La hipótesis dinámica establecida fue: “El comportamiento dinámico de planeación e implementación de tecnología genera un efecto en la transformación, calidad, asignación de recursos, inventarios y trazabilidad del sistema (cadena de suministros frutícola”. El modelo causal fue obtenido a partir de una detallada y rigurosa revisión de la literatura y de estudios específicos del sector de frutas en Colombia, sobre el tema de la trazabilidad en la cadena de suministro de alimentos a partir de las perspectivas de dinámica de sistemas, integración, optimización y tecnologías de trazabilidad. Existen pocos trabajos en trazabilidad con un enfoque como el abordado en este trabajo. El desarrollo permitió incluir, en los diagramas causales, una serie de factores no tenidos en cuenta en trabajos previos. Los resultados obtenidos a través del análisis causal propuesto, bajo la metodología de dinámica de sistemas, implican la inclusión del efecto de la implementación de tecnología de trazabilidad en la cadena de suministro de frutas y sus relaciones con la capacidad de inversión y la calidad de un producto.

Accurate measurement of transgene copy number in crop plants using droplet digital PCR.

Science.gov (United States)

Collier, Ray; Dasgupta, Kasturi; Xing, Yan-Ping; Hernandez, Bryan Tarape; Shao, Min; Rohozinski, Dominica; Kovak, Emma; Lin, Jeanie; de Oliveira, Maria Luiza P; Stover, Ed; McCue, Kent F; Harmon, Frank G; Blechl, Ann; Thomson, James G; Thilmony, Roger

2017-06-01

Genetic transformation is a powerful means for the improvement of crop plants, but requires labor- and resource-intensive methods. An efficient method for identifying single-copy transgene insertion events from a population of independent transgenic lines is desirable. Currently, transgene copy number is estimated by either Southern blot hybridization analyses or quantitative polymerase chain reaction (qPCR) experiments. Southern hybridization is a convincing and reliable method, but it also is expensive, time-consuming and often requires a large amount of genomic DNA and radioactively labeled probes. Alternatively, qPCR requires less DNA and is potentially simpler to perform, but its results can lack the accuracy and precision needed to confidently distinguish between one- and two-copy events in transgenic plants with large genomes. To address this need, we developed a droplet digital PCR-based method for transgene copy number measurement in an array of crops: rice, citrus, potato, maize, tomato and wheat. The method utilizes specific primers to amplify target transgenes, and endogenous reference genes in a single duplexed reaction containing thousands of droplets. Endpoint amplicon production in the droplets is detected and quantified using sequence-specific fluorescently labeled probes. The results demonstrate that this approach can generate confident copy number measurements in independent transgenic lines in these crop species. This method and the compendium of probes and primers will be a useful resource for the plant research community, enabling the simple and accurate determination of transgene copy number in these six important crop species. Published 2017. This article is a U.S. Government work and is in the public domain in the USA.

Copy number variation analysis of matched ovarian primary tumors and peritoneal metastasis.

Directory of Open Access Journals (Sweden)

Joel A Malek

Full Text Available Ovarian cancer is the most deadly gynecological cancer. The high rate of mortality is due to the large tumor burden with extensive metastatic lesion of the abdominal cavity. Despite initial chemosensitivity and improved surgical procedures, abdominal recurrence remains an issue and results in patients' poor prognosis. Transcriptomic and genetic studies have revealed significant genome pathologies in the primary tumors and yielded important information regarding carcinogenesis. There are, however, few studies on genetic alterations and their consequences in peritoneal metastatic tumors when compared to their matched ovarian primary tumors. We used high-density SNP arrays to investigate copy number variations in matched primary and metastatic ovarian cancer from 9 patients. Here we show that copy number variations acquired by ovarian tumors are significantly different between matched primary and metastatic tumors and these are likely due to different functional requirements. We show that these copy number variations clearly differentially affect specific pathways including the JAK/STAT and cytokine signaling pathways. While many have shown complex involvement of cytokines in the ovarian cancer environment we provide evidence that ovarian tumors have specific copy number variation differences in many of these genes.

Dinámica y distribución de la productividad del trabajo en México después de la apertura comercial

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Luis Gutiérrez-Flores

2016-01-01

Full Text Available El presente documento analiza la dinámica en la distribución de la productividad en las entidades federativas de México para el periodo 1994-2009. El objetivo central de la investigación es conocer si el proceso dinámico de distribución de la productividad del sector manufacturero, con el uso de las cadenas de Markov, tiene un patrón similar o no al encontrado cuando se discute acerca de la convergencia en ingresos. Los resultados del trabajo indican una tendencia no únicamente hacia la concentración de la actividad manufacturera del país, sino también hacia una separación en los niveles de productividad en los años recientes.

Gestión de la cadena de suministros desde la dinámica de sistemas. Aproximación al mejoramiento de la toma de decisiones

OpenAIRE

Brijaldo Oliveros, Felipe Orlando

2015-01-01

El objetivo de este trabajo es hacer un estudio sobre la cadena de suministros en organizaciones empresariales desde la Dinámica de Sistemas y como esta puede aportar al desempeño y el control de las cadenas de suministros. Se buscará Abordar el cocimiento sobre tres perspectivas de Supply Chain y su relación con la dinámica de sistemas. También se buscará identificar los tipos de integración en las actividades de la gestión en la cadena de suministros y sus horizontes de planeación. Por últi...

Investigation of Copy Number Variation in Children with Conotruncal Heart Defects

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Carla Marques Rondon Campos

2015-01-01

Full Text Available Background: Congenital heart defects (CHD are the most prevalent group of structural abnormalities at birth and one of the main causes of infant morbidity and mortality. Studies have shown a contribution of the copy number variation in the genesis of cardiac malformations. Objectives: Investigate gene copy number variation (CNV in children with conotruncal heart defect. Methods: Multiplex ligation-dependent probe amplification (MLPA was performed in 39 patients with conotruncal heart defect. Clinical and laboratory assessments were conducted in all patients. The parents of the probands who presented abnormal findings were also investigated. Results: Gene copy number variation was detected in 7/39 patients: 22q11.2 deletion, 22q11.2 duplication, 15q11.2 duplication, 20p12.2 duplication, 19p deletion, 15q and 8p23.2 duplication with 10p12.31 duplication. The clinical characteristics were consistent with those reported in the literature associated with the encountered microdeletion/microduplication. None of these changes was inherited from the parents. Conclusions: Our results demonstrate that the technique of MLPA is useful in the investigation of microdeletions and microduplications in conotruncal congenital heart defects. Early diagnosis of the copy number variation in patients with congenital heart defect assists in the prevention of morbidity and decreased mortality in these patients.

Reconfigurando aplicaciones multi-cloud con líneas de producto software dinámicas

OpenAIRE

Cubo, Javier; Gámez,Nadia; Pimentel, Ernesto; Fuentes, Lidia

2016-01-01

La reconfiguración dinámica de aplicaciones multi-cloud es un reto complejo aún no suficientemente explorado. En estos entornos las aplicaciones o sus módulos pueden estar desplegados en diferentes proveedores. Por lo tanto, reconfigurar en tiempo de ejecución estas aplicaciones puede requerir la modificación de la distribución en múltiples y heterogéneos proveedores. Obtener la nueva distribución para que sigan funcionando correctamente las aplicaciones no es una tarea senc...

The cost of copy number in a selfish genetic element: the 2-μm plasmid of Saccharomyces cerevisiae.

Science.gov (United States)

Harrison, Ellie; Koufopanou, V; Burt, A; MacLean, R C

2012-11-01

Many autonomously replicating genetic elements exist as multiple copies within the cell. The copy number of these elements is often assumed to have important fitness consequences for both element and host, yet the forces shaping its evolution are not well understood. The 2 μm is a multicopy plasmid of Saccharomyces yeasts, encoding just four genes that are solely involved in plasmid replication. One simple model for the fitness relationship between yeasts and 2 μm is that plasmid copy number evolves as a trade-off between selection for increased vertical transmission, favouring high copy number, and selection for decreased virulence, favouring low copy number. To test this model, we experimentally manipulated the copy number of the plasmid and directly measured the fitness cost, in terms of growth rate reduction, associated with high plasmid copy number. We find that the fitness burden imposed by the 2 μm increases with plasmid copy number, such that each copy imposes a fitness burden of 0.17% (± 0.008%), greatly exceeding the cost expected for it to be stably maintained in yeast populations. Our results demonstrate the crucial importance of copy number in the evolution of yeast per 2 μm associations and pave the way for future studies examining how selection can shape the cost of multicopy elements. © 2012 The Authors. Journal of Evolutionary Biology © 2012 European Society For Evolutionary Biology.

Dinámica de la fuerza de trabajo en Cuba 1846-1931 (II

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Orestes Gárciga Gárciga

2014-06-01

Full Text Available En «Dinámica de la fuerza de trabajo en Cuba 1846-1931» se estudia el procesamiento de los datos estadísticos que, acerca de la actividad laboral de la población, presentaron los censos de 1846, 1862, 1899, 1907, 1919 y 1931. Debido a su extensión, la obra ha sido dividida en tres partes para ser publicada en Novedades en Población. El presente artículo examina la evolución de la fuerza de trabajo en Cuba de 1846 a 1931, a través de diversas clasificaciones internacionales empleadas en estos estudios, y da continuidad a «Dinámica de la fuerza de trabajo en Cuba 1846-1931 (I», incluido en el número anterior de la revista (Año 9, Número 17, 2013. Abstract In «Dynamic of the workforce in Cuba 1846-1931» is studied the processing of statistical data showed by the 1846, 1862, 1899, 1907, 1919 and 1931 censuses about labor activity of the population. Due to its extension, this work has been divided in three parts so it can be published in Novedades en Población (News on Population. The current paper reviews the evolution of the work force in Cuba from 1846 to 1931, taking to account diverse international classifications used in this studies. It is the continuation of «Dynamic of the workforce in Cuba 1846-1931 (I», included in the previous number of this magazine.

A dinâmica dos homicídios no Nordeste e em Pernambuco

Directory of Open Access Journals (Sweden)

José Maria Nóbrega Júnior

2010-10-01

Full Text Available O objetivo deste artigo é analisar a dinâmica das mortes por homicídio no Nordeste, região mais violenta do país em termos desse tipo de crime. Indicadores de homicídios foram analisados para todos os estados nordestinos, com ênfase em Pernambuco. A análise dos números demonstra um crescimento das mortes violentas e intencionais na região pelo menos desde o início da década de 1990, com maior impacto nos últimos 10 anos, chegando a ultrapassar os números do Sudeste em 2006. Buscou-se tabular esses números por grupos como faixa etária, nível de escolaridade e por regiões de Pernambuco, revelando-se as diferentes dimensões dessa dinâmica. The aim of the article The dynamics of homicides in the Northeast and Pernambuco is to review the dynamics of deaths by homicide in the Northeast ofBrazil, the most violent region in the country in terms of this kind of crime. Murder rates were analysed for all the North-eastern states, with special focus on Pernambuco. The statistical analysis shows a growth in violent and intentional deaths in the region at least since the start of the 1990s, peaking in the last 10 years and surpassing the figures for the Southeast in 2006. Associations were then sought with groups like age group, level of schooling and by regions of Pernambuco, revealing the different dimensions of the dynamics.

El control de sistemas dinámicos caóticos en economía: aplicación a un modelo de hiperinflación

Directory of Open Access Journals (Sweden)

Graciela Chaparro Guevara

2015-10-01

Full Text Available El presente artículo tiene por objetivo estudiar el control del comportamiento caótico de un sistema dinámico de hiperinflación empleando el método propuesto por Ott, Grebogy y Yorke (1990 (método OGY, el cual busca controlar la dinámica caótica de un sistema perturbando levemente alguno de sus parámetros. El método se ejemplificará por medio de la aplicación logística, y posteriormente se empleará en un modelo de hiperinflación (Punita, 2011 para estabilizar los precios en una órbita estacionaria de periodo uno.

1 CFR 3.3 - Reproduction and certification of copies of acts and documents.

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2010-01-01

... 1 General Provisions 1 2010-01-01 2010-01-01 false Reproduction and certification of copies of... GENERAL SERVICES TO THE PUBLIC § 3.3 Reproduction and certification of copies of acts and documents. The... furnishing of reproductions of acts and documents and certificates of authentication for them. Section 1258...

La importancia del diagnóstico dinámico en la práctica clínica

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Roberto Anselmo Ramos Valverde

2014-08-01

Full Text Available El enfoque biologicista quedó teóricamente quebrantado con dos aportes fundamentales: la medicina psicosomática,que destacó la relación mente-soma como un sistema lineal de relaciones mutuas bidireccionales, señalando el papel de los factores psicológicos en la génesis de las enfermedades; y el reconocimiento por la Medicina de los factores sociales, influyentes en el proceso salud enfermedad, puente de enlace con las ciencias sociales. (1 Anteriormente el intento más acabado lo constituyeronlas series complementarias de Freud, un legado a la teoría de la causalidad y al enfoque dinámico, acercándose bastante al modelo recíproco. Una primera serie incluye los factores hereditarios y congénitos, una segunda serie constituida por las experiencias infantiles, que al interrelacionarse con la primera conforma la disposición o condición interna existente en el sujeto, la cual al interactuar con los factores desencadenantes del medio, representantes de la tercera serie,produce el efecto conductual,explicándose de esta manera el comportamiento normal y el anómalo. (1 Se trata de diagnóstico dinámico para significar el conjunto de factores etiopatogénicos biológicos, psicológicos y sociales que interactúan dialécticamente,cuyo resultado final es la enfermedad. La psicopatología, disciplina de la Psiquiatría dedicada al estudio de las causas, origen y desarrollo de los trastornos mentales, legó a la clínica psiquiátrica este modelo, que puede ser extendido a otras ramas de la medicina, para comprender al enfermo en su integridad humana y cumplir con el principio de personalizar la atención médica, al tratar enfermos, no enfermedades, sin pretender generalizar este diagnóstico como panacea heurística en la medicina clínica, donde el enfermo es la unidad básica de estudio. (1,2 El diagnóstico dinámico permite un análisis casuístico, recíproco y dialéctico, capaz de penetrar en el drama humano y descifrar las

Sparse representation and Bayesian detection of genome copy number alterations from microarray data.

Science.gov (United States)

Pique-Regi, Roger; Monso-Varona, Jordi; Ortega, Antonio; Seeger, Robert C; Triche, Timothy J; Asgharzadeh, Shahab

2008-02-01

Genomic instability in cancer leads to abnormal genome copy number alterations (CNA) that are associated with the development and behavior of tumors. Advances in microarray technology have allowed for greater resolution in detection of DNA copy number changes (amplifications or deletions) across the genome. However, the increase in number of measured signals and accompanying noise from the array probes present a challenge in accurate and fast identification of breakpoints that define CNA. This article proposes a novel detection technique that exploits the use of piece wise constant (PWC) vectors to represent genome copy number and sparse Bayesian learning (SBL) to detect CNA breakpoints. First, a compact linear algebra representation for the genome copy number is developed from normalized probe intensities. Second, SBL is applied and optimized to infer locations where copy number changes occur. Third, a backward elimination (BE) procedure is used to rank the inferred breakpoints; and a cut-off point can be efficiently adjusted in this procedure to control for the false discovery rate (FDR). The performance of our algorithm is evaluated using simulated and real genome datasets and compared to other existing techniques. Our approach achieves the highest accuracy and lowest FDR while improving computational speed by several orders of magnitude. The proposed algorithm has been developed into a free standing software application (GADA, Genome Alteration Detection Algorithm). http://biron.usc.edu/~piquereg/GADA

Diseño de escenarios virtuales para problemas de optimización a través de geometría dinámica.

Directory of Open Access Journals (Sweden)

Freddy Yesid Villamizar Araque

2018-04-01

Full Text Available El presente artículo tiene el objetivo de analizar la influencia del uso de tecnologías digitales, particularmente, de software de geometría dinámica, acompañado de una didáctica en la concepción y solución de problemas aplicados, en un enfoque de enseñanza activa, en temas de optimización. La metodología siguió un enfoque cualitativo, se desarrolló a partir de taller con profesores, en el cual se resolvieron problemas en el contexto de máximos y mínimos de forma analítica y dinámica mediante el software geogebra. Resultados señalan la necesidad de implementar secuencias didácticas que guíen al a la concepción de optimización, la herramienta motiva la fase de enseñanza al permitir la simulación, modifica heurísticas y formas de solucionar un problema. Conclusión: la tecnología digital es factor motivante en la enseñanza, permite la visualización de representaciones de objetos matemáticos de manera dinámica, ayuda a la conceptualización si y solo si se apoya de secuencias didácticas.

International Journal of Basic, Applied and Innovative Research ...

African Journals Online (AJOL)

Sources of Support. Article publication charges, Sale of hard copies and subscriptions. * All accepted articles for publication in IJBAIR attracts an article processing fee of $85 or its Naira equivalent. Hard Copies Produced at the end of the Publication Year shall be sent at no cost to the principal authors. However, extra ...

78 FR 22527 - Army Science Board Request for Information on Technology and Core Competencies

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2013-04-16

... require both a CD and a hard copy of the response. The size of the CD submission will be limited to 20 MB. The hard copy format specifications include 12 point font, single-spaced, single-sided, 8.5 by 11... universities. Submission Instructions and Format: To respond to this request for information, interested...

34 CFR 668.24 - Record retention and examinations.

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2010-07-01

... representative. (3) An institution may keep required records in hard copy or in microform, computer file, optical disk, CD-ROM, or other media formats, provided that— (i) Except for the records described in paragraph (d)(3)(ii) of this section, all record information must be retrievable in a coherent hard copy format...

77 FR 2456 - Incorporation of Revised ASTM Standards That Provide Flexibility in the Use of Alternatives to...

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2012-01-18

... will be publicly available only in hard copy form. Publicly available docket materials are available in the electronic docket at http://www.regulations.gov , or, if only available in hard copy, at the OPPT... 40 CFR part 86. B. Formatting Changes to Final Rule The regulatory text of this final rule is...

78 FR 52473 - Approval and Promulgation of Implementation Plans; New Mexico; Prevention of Significant...

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2013-08-23

... copyrighted material, will be publicly available only in hard copy. Publicly available docket materials are available either electronically in http://www.regulations.gov or in hard copy at the Air Permits Section..., Non-substantive revisions to 20.2.74.7(AZ)(1), (2), (2)(b), (3), (4), and (5) to correct formatting...

76 FR 79173 - Registration Review; Pesticide Dockets Opened for Review and Comment, and Notice of Availability...

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2011-12-21

... placed on the Internet and will be publicly available only in hard copy form. Publicly available docket... available in hard copy, at the OPP Regulatory Public Docket in Rm. S-4400, One Potomac Yard (South Bldg.... Section 3(g) of FIFRA provides, among other things, that the registrations of pesticides are to be...

76 FR 60822 - Registration Review; Pesticide Dockets Opened for Review and Comment and Other Docket Actions

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2011-09-30

... placed on the Internet and will be publicly available only in hard copy form. Publicly available docket... available in hard copy, at the OPP Regulatory Public Docket in Rm. S-4400, One Potomac Yard (South Bldg... 155, subpart C. Section 3(g) of FIFRA provides, among other things, that the registrations of...

78 FR 41311 - Approval of Air Quality Implementation Plans; Indiana; Approval of “Infrastructure” SIP With...

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2013-07-10

... copyrighted material, will be publicly-available only in hard copy. Publicly-available docket materials are available either electronically in www.regulations.gov or in hard copy at the U.S. Environmental Protection... SIP at 326 IAC 1-3-4(b)(8) that among other things, contained the Federally promulgated 2006 PM 2.5...

78 FR 37261 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing of...

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2013-06-20

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76 FR 39399 - Chlorpyrifos Registration Review; Preliminary Human Health Risk Assessment; Notice of Availability

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2011-07-06

... placed on the Internet and will be publicly available only in hard copy form. Publicly available docket... available in hard copy, at the OPP Regulatory Public Docket in Rm. S-4400, One Potomac Yard (South Bldg... 40 CFR part 155, subpart C. Section 3(g) of FIFRA provides, among other things, that the...

75 FR 39934 - Oil and Natural Gas Sector-Notice of Public Meeting

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2010-07-13

... an electronic or hard copy of any prepared comments be provided to EPA at the time of the meeting... materials are available either electronically through www.regulations.gov or in hard copy at the EPA Docket... requires, among other things, that EPA sign by January 31, 2011, proposed standards and/or determinations...

78 FR 46816 - Approval and Promulgation of Air Quality Implementation Plans; State of Colorado; Second Ten-Year...

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2013-08-02

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Dinámica y crecimiento de los granos de polvo en la nebulosa protoplanetaria

Science.gov (United States)

de La Fuente Marcos, Carlos

2001-06-01

En el escenario estándar de la formación planetaria, los planetesimales (cuerpos de tamaño kilométrico) crecen a partir de granos de polvo, similares a los interestelares, embebidos en un disco gaseoso denominado nebulosa protoplanetaria. Durante esta etapa, los movimientos del gas pueden tener gran influencia en la dinámica y el crecimiento de los granos de polvo, dado que el flujo kepleriano del gas frena el movimiento de los mismos haciendo que caigan hacia el Sol, y la turbulencia inhibe la inestabilidad gravitacional de la capa de polvo. Aunque se acepta que los planetesimales fueron los elementos constituyentes de los planetas, todavía se desconoce cómo se produjo la formación de los mismos. Por esta razón, en los estudios más recientes, existe un renovado interés por comprender mejor la evolución de la capa de polvo inmersa en el disco gaseoso de la Nebulosa. El gas que fluye en el disco puede engendrar estructuras carentes de simetría axial, como por ejemplo ondas espirales y vórtices, a partir de gran variedad de mecanismos de excitación e inestabilidad. En 1995, Barge y Sommeria pusieron de manifiesto que la existencia de vórtices gaseosos persistentes en la nebulosa solar tendría importantes consecuencias sobre la formación de los planetesimales y el posterior crecimiento de los planetas gigantes. La investigación desarrollada en esta Tesis analiza la relación entre el polvo y el gas debida al acoplamiento por fricción dinámica entre ambos; en concreto, se estudia el efecto del flujo medio del gas sobre la dinámica de las partículas de polvo. El primer objetivo es investigar en profundidad los procesos de captura y crecimiento de los granos de polvo dentro de un vórtice y su posible relevancia en cuanto a la formación de los planetesimales. El segundo objetivo es la exploración de los efectos de ondas espirales propagándose en el disco gaseoso sobre la dinámica y el crecimiento de las partículas. La presencia de líneas de

Generación y dinámica de electrones runaway en plasmas tokamak

OpenAIRE

Fernández Gómez, Isabel

2016-01-01

La dinámica y generación de electrones runaway en plasmas tokamak constituye el tema central de esta tesis. En un tokamak, el fenómeno runaway es el resultado de la existencia de un campo eléctrico en dirección toroidal. Aquellos electrones cuya velocidad excede un cierto valor crítico se aceleran de forma continua, ya que la e ciencia de las colisiones para disipar la energía ganada en el campo disminuye con la velocidad (∼ ⁻¹) . Se tiene entonces lo que se conoce como un electrón runaway. ...

Non-fluent speech following stroke is caused by impaired efference copy.

Science.gov (United States)

Feenaughty, Lynda; Basilakos, Alexandra; Bonilha, Leonardo; den Ouden, Dirk-Bart; Rorden, Chris; Stark, Brielle; Fridriksson, Julius

2017-09-01

Efference copy is a cognitive mechanism argued to be critical for initiating and monitoring speech: however, the extent to which breakdown of efference copy mechanisms impact speech production is unclear. This study examined the best mechanistic predictors of non-fluent speech among 88 stroke survivors. Objective speech fluency measures were subjected to a principal component analysis (PCA). The primary PCA factor was then entered into a multiple stepwise linear regression analysis as the dependent variable, with a set of independent mechanistic variables. Participants' ability to mimic audio-visual speech ("speech entrainment response") was the best independent predictor of non-fluent speech. We suggest that this "speech entrainment" factor reflects integrity of internal monitoring (i.e., efference copy) of speech production, which affects speech initiation and maintenance. Results support models of normal speech production and suggest that therapy focused on speech initiation and maintenance may improve speech fluency for individuals with chronic non-fluent aphasia post stroke.

Initiative hard coal; Initiative Steinkohle

Energy Technology Data Exchange (ETDEWEB)

Leonhardt, J.

2007-08-02

In order to decrease the import dependence of hard coal in the European Union, the author has submitted suggestions to the director of conventional sources of energy (directorate general for energy and transport) of the European community, which found a positive resonance. These suggestions are summarized in an elaboration 'Initiative Hard Coal'. After clarifying the starting situation and defining the target the presupposition for a better use of hard coal deposits as raw material in the European Union are pointed out. On that basis concrete suggestions for measures are made. Apart from the conditions of the deposits it concerns thereby also new mining techniques and mining-economical developments, connected with tasks for the mining-machine industry. (orig.)

Hard diffraction and rapidity gaps

International Nuclear Information System (INIS)

Brandt, A.

1995-09-01

The field of hard diffraction, which studies events with a rapidity gap and a hard scattering, has expanded dramatically recently. A review of new results from CDF, D OE, H1 and ZEUS will be given. These results include diffractive jet production, deep-inelastic scattering in large rapidity gap events, rapidity gaps between high transverse energy jets, and a search for diffractive W-boson production. The combination of these results gives new insight into the exchanged object, believed to be the pomeron. The results axe consistent with factorization and with a hard pomeron that contains both quarks and gluons. There is also evidence for the exchange of a strongly interacting color singlet in high momentum transfer (36 2 ) events

Innovación incremental basada en capacidades dinámicas. Evidencia empírica en las empresas peruanas

Directory of Open Access Journals (Sweden)

Alejandro Flores Castro

2015-09-01

Full Text Available Los resultados macroeconómicos logrados por el Perú en los últimos años, hacen prever uncrecimiento de la actividad empresarial desde la perspectiva de sus capacidades a fin dealcanzar posiciones de ventaja. Sin embargo, este crecimiento estará basado esencialmenteen procesos de mejora, no vislumbrándose un aporte significativo de parte de las empresasa desarrollar procesos de innovación radical o disruptiva, abocándose preferentemente aprocesos de innovación incremental o de bajo impacto. En la primera parte del documentose aborda el tema de la innovación como factor de ventaja competitiva basado en un modelode capacidades dinámicas, en el contexto de la teoría de recursos y capacidades, analizandolos diferentes modelos de innovación tecnológica. En la segunda parte del trabajo se presentaun modelo de innovación basada en capacidades dinámicas. Y finalmente se presenta lametodología y los resultados del el estudio empírico acerca de los procesos de innovaciónincremental que se dan en las empresas peruanas.

Innovación incremental basada en capacidades dinámicas. Evidencia empírica en las empresas peruanas

Directory of Open Access Journals (Sweden)

Alejandro Flores Castro

2011-06-01

Full Text Available Los resultados macroeconómicos logrados por el Perú en los últimos años, hacen prever uncrecimiento de la actividad empresarial desde la perspectiva de sus capacidades a fin dealcanzar posiciones de ventaja. Sin embargo, este crecimiento estará basado esencialmenteen procesos de mejora, no vislumbrándose un aporte significativo de parte de las empresasa desarrollar procesos de innovación radical o disruptiva, abocándose preferentemente aprocesos de innovación incremental o de bajo impacto. En la primera parte del documentose aborda el tema de la innovación como factor de ventaja competitiva basado en un modelode capacidades dinámicas, en el contexto de la teoría de recursos y capacidades, analizandolos diferentes modelos de innovación tecnológica. En la segunda parte del trabajo se presentaun modelo de innovación basada en capacidades dinámicas. Y finalmente se presenta lametodología y los resultados del el estudio empírico acerca de los procesos de innovaciónincremental que se dan en las empresas peruanas.

Two new statistics to detect answer copying

NARCIS (Netherlands)

Meijer, R.R.; Sotaridona, Leonardo

2001-01-01

Two new indices to detect answer copying on a multiple-choice test, S(1) and S(2) (subscripts), are proposed. The S(1) index is similar to the K-index (P. Holland, 1996) and the K-overscore(2), (K2) index (L. Sotaridona and R. Meijer, in press), but the distribution of the number of matching

Two new indices to detect answer copying

NARCIS (Netherlands)

Sotaridona, Leonardo; Meijer, R.R.

2003-01-01

Two new indices to detect answer copying on a multiple-choice test—S1 and S2—were proposed. The S1 index is similar to the K index (Holland, 1996) and the K2 index (Sotaridona & Meijer, 2002) but the distribution of the number of matching incorrect answers of the source and the copier is modeled by

Genetic analysis of kernel texture (grain hardness) in a hard red spring wheat (Triticum aestivum L.) bi-parental population

Science.gov (United States)

Grain hardness is a very important trait in determining wheat market class and also influences milling and baking traits. At the grain Hardness (Ha) locus on chromosome 5DS, there are two primary mutations responsible for conveying a harder kernel texture among U.S. hard red spring wheats: (1) the P...

Inferring mechanisms of copy number change from haplotype structures at the human DEFA1A3 locus

OpenAIRE

Black, Holly A; Khan, Fayeza F; Tyson, Jess; Armour, John AL

2014-01-01

Background The determination of structural haplotypes at copy number variable regions can indicate the mechanisms responsible for changes in copy number, as well as explain the relationship between gene copy number and expression. However, obtaining spatial information at regions displaying extensive copy number variation, such as the DEFA1A3 locus, is complex, because of the difficulty in the phasing and assembly of these regions. The DEFA1A3 locus is intriguing in that it falls within a reg...

Monitoring of dams according to German standard DIN 19 700 on the basis of a GIS based expert system; Stauanlagenueberwachung nach DIN 19 700 in Verbindung mit Expertensystemen auf GIS-Basis

Energy Technology Data Exchange (ETDEWEB)

Kast, Karl; Saucke, Ulrich; Elsaesser, Ralph [Dr.-Ing. Karl Kast + Partner (GbR) Ingenieurgemeinschaft fuer Umwelt- und Geotechnik, Ettlingen (Germany)

2010-07-01

The German standard DIN 19 700 stipulates regular safety reports assessing dams and their operation as part of the continuous dam monitoring scheme. Experience has shown that a GIS based dam monitoring system exhibits evident advantages regarding a continuous assessment. Besides and easy access to all relevant information grouped by themes, it offers a graphic analysis of measuring data and their display in the GIS system. In addition, concerning relevant failure mechanism, individual modules of a GIS based expert system are designed for the purpose of assessing the safety of the dam in the event of uncommon incidents. (orig.)

Filme din ţările Puterilor Centrale pe ecranele din Bucureștii ocupaţi (1916–1918

Directory of Open Access Journals (Sweden)

Adrian-Silvan Ionescu

2016-10-01

Full Text Available Once Romania joined the war, alongside with the Allies, by the end of the summer of 1916, the cinema theatres were closed, like all other places of entertainment. This was a significant blow to townsfolk used to spend their free time in theatre halls. However, it did not last long, because on September 11, they are reopened on special schedules, only from 3 to 6 p.m. In the first days of October, patriotic and propaganda films like „Martiriul Românilor din Ardeal” (The Martyrdom of Romanians in Transylvania, were being run. In the first decade of the next month, there was announced the work on the „historic and patriotic film the Great War for the Liberation of the Romanian Nation”, which followed to contain scenes of the recent fighting on the front. The film was expected to be released on November 14 at Zaharia cinema theatre. However, the situation on the front was not favourable for the Romanian armies and soon the enemy occupied the south of the country. The German occupational civil and military administration intended to make of Romania an example of good management and judicious care for the welfare and contentment of mind of the residents – even if all this was mere propaganda.

On quasi-conformal (in-) compatibility of satellite copies of the Mandelbrot set: I

DEFF Research Database (Denmark)

Lomonaco, Luna; Petersen, Carsten Lunde

2017-01-01

Douady and Hubbard (Ann Sci Ec Norm Suppl 4 18(2):287–343, 1985) introduced the notion of polynomial-like maps. They used it to identify homeomorphic copies M of the Mandelbrot set inside the Mandelbrot set M. These copies can be primitive (with a root cusp) or satellite (without a root cusp). Th...